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Sample records for policy study serial

  1. Serial neuroradiological studies in focal cerebritis

    International Nuclear Information System (INIS)

    Hatta, S.; Mochizuki, H.; Kuru, Y.; Miwa, H.; Kondo, T.; Mori, H.; Mizuno, Y.

    1994-01-01

    We report serial neuroradiological studies in a patient with focal cerebritis in the head of the left caudate nucleus. On the day after the onset of symptoms, CT showed an ill-defined low density lesion. The lack of contrast enhancement appeared to be the most important finding for differentiating focal cerebritis from an encapsulated brain abscess or a tumour. MRI two days later revealed the centre of the lesion to be of slightly low intensity on T1-weighted inversion recovery (IR) images and very low intensity on T2-weighted spin echo images, which appeared to correspond to the early cerebritis stage of experimentally induced cerebritis and brain abscess. Ten days after the onset of symptoms, CT revealed a thin ring of enhancement in the head of the caudate nucleus, and a similar small ring was seen in the hypothalamus 16 days after the onset, corresponding to the late cerebritis stage. MRI nine days later revealed ill-defined high signal lesions within the involved area on the T1-weighted IR images. To our knowledge, this is the first published MRI documentation of the early cerebritis stage developing into an encapsulated brain abscess. The mechanisms underlying of these radiographic changes are discussed. (orig.)

  2. Serial MRI studies using gadolinium DTPA in active multiple sclerosis

    International Nuclear Information System (INIS)

    Miller, D.H.; Johnson, G.; Barnes, D.; Rudge, P.; McDonald, W.I.

    1988-01-01

    It has been suggested that blood brain barrier (BBB) impairment is a necessary early event in the pathogenesis of the multiple sclerosis (MS) lesions. To evaluate such an hypothesis in vivo would require: (1) serial imaging studies using a modality with high sensitivity for detecting plaques; (2) a contrast enhancing agent which demonstrates BBB impairment. A serial magnetic resonance imaging (MRI) study was undertaken of a group of MS patients using the contrast agent gadolinium-DTPA. As it has been suggested that T 1 and T 2 relaxation times are longer in acute than chronic MS lesions, these were also measured. 3 refs.; 1 figure

  3. Serial volumetric registration of pulmonary CT studies

    Science.gov (United States)

    Silva, José Silvestre; Silva, Augusto; Sousa Santos, Beatriz

    2008-03-01

    Detailed morphological analysis of pulmonary structures and tissue, provided by modern CT scanners, is of utmost importance as in the case of oncological applications both for diagnosis, treatment, and follow-up. In this case, a patient may go through several tomographic studies throughout a period of time originating volumetric sets of image data that must be appropriately registered in order to track suspicious radiological findings. The structures or regions of interest may change their position or shape in CT exams acquired at different moments, due to postural, physiologic or pathologic changes, so, the exams should be registered before any follow-up information can be extracted. Postural mismatching throughout time is practically impossible to avoid being particularly evident when imaging is performed at the limiting spatial resolution. In this paper, we propose a method for intra-patient registration of pulmonary CT studies, to assist in the management of the oncological pathology. Our method takes advantage of prior segmentation work. In the first step, the pulmonary segmentation is performed where trachea and main bronchi are identified. Then, the registration method proceeds with a longitudinal alignment based on morphological features of the lungs, such as the position of the carina, the pulmonary areas, the centers of mass and the pulmonary trans-axial principal axis. The final step corresponds to the trans-axial registration of the corresponding pulmonary masked regions. This is accomplished by a pairwise sectional registration process driven by an iterative search of the affine transformation parameters leading to optimal similarity metrics. Results with several cases of intra-patient, intra-modality registration, up to 7 time points, show that this method provides accurate registration which is needed for quantitative tracking of lesions and the development of image fusion strategies that may effectively assist the follow-up process.

  4. Serial murder in America: case studies of seven offenders.

    Science.gov (United States)

    Beasley, James O

    2004-01-01

    This article summarizes and compares information on seven interviewed serial killers in an ongoing project designed to study similarities and differences among these individuals. The aim of this article is to increase our collective knowledge of the dynamics of serial murder by examining the perpetrators' backgrounds, as well as the unique ways in which they view themselves and the world around them. Although qualitative interview research alone is not sufficient to fully understand such behavior, it is useful in many ways. Some of the information discussed based on the seven offenders interviewed is compared with broader epidemiological studies, and the strengths and limitations of each type of research are discussed. Published in 2004 by John Wiley & Sons, Ltd.

  5. Serial-order short-term memory predicts vocabulary development: evidence from a longitudinal study.

    Science.gov (United States)

    Leclercq, Anne-Lise; Majerus, Steve

    2010-03-01

    Serial-order short-term memory (STM), as opposed to item STM, has been shown to be very consistently associated with lexical learning abilities in cross-sectional study designs. This study investigated longitudinal predictions between serial-order STM and vocabulary development. Tasks maximizing the temporary retention of either serial-order or item information were administered to kindergarten children aged 4 and 5. At age 4, age 5, and from age 4 to age 5, serial-order STM capacities, but not item STM capacities, were specifically associated with vocabulary development. Moreover, the increase of serial-order STM capacity from age 4 to age 5 predicted the increase of vocabulary knowledge over the same time period. These results support a theoretical position that assumes an important role for serial-order STM capacities in vocabulary acquisition.

  6. Serial Analysis of Gene Expression: Applications in Human Studies

    Directory of Open Access Journals (Sweden)

    Tuteja Renu

    2004-01-01

    Full Text Available Serial analysis of gene expression (SAGE is a powerful tool, which provides quantitative and comprehensive expression profile of genes in a given cell population. It works by isolating short fragments of genetic information from the expressed genes that are present in the cell being studied. These short sequences, called SAGE tags, are linked together for efficient sequencing. The frequency of each SAGE tag in the cloned multimers directly reflects the transcript abundance. Therefore, SAGE results in an accurate picture of gene expression at both the qualitative and the quantitative levels. It does not require a hybridization probe for each transcript and allows new genes to be discovered. This technique has been applied widely in human studies and various SAGE tags/SAGE libraries have been generated from different cells/tissues such as dendritic cells, lung fibroblast cells, oocytes, thyroid tissue, B-cell lymphoma, cultured keratinocytes, muscles, brain tissues, sciatic nerve, cultured Schwann cells, cord blood-derived mast cells, retina, macula, retinal pigment epithelial cells, skin cells, and so forth. In this review we present the updated information on the applications of SAGE technology mainly to human studies.

  7. A study on the utilization of serial resources in selected tertiary ...

    African Journals Online (AJOL)

    A study on the utilization of serial resources in selected tertiary institutions in Ogun State. ... Lagos Journal of Library and Information Science ... Serial resources are publications either in printed form or electronic format issued in successive parts usually having numerical or chronological designations and intended to be ...

  8. Which serial killers commit suicide? An exploratory study.

    Science.gov (United States)

    Lester, David; White, John

    2012-11-30

    In a sample of 483 serial killers, 6.2% were documented to have committed suicide. Those who committed suicide were found to come from more dysfunctional homes characterized by more psychiatric disturbance in the parents. The sexual acts involved in the murders by the suicides seemed to be more deviant in some aspects, such as committing more bizarre sexual acts or more often taping the murder. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  9. Single Policy Study

    DEFF Research Database (Denmark)

    Kronsell, Annica; Manners, Ian James

    2015-01-01

    Single policy studies are the most common form of European Union (EU) research. Single policy studies are widely used to understand the role of the EU in a wide variety of sectors, together with their development over time, and often offer public policy prescriptions. This chapter discusses...... the relevance of single policy studies in EU research and give examples of how such research can be designed and carried out. The chapter reviews three examples of single policy studies using different methods based on EU environmental policy, the EU biofuels directive, and the EU Common Security and Defence...... Policy (CSDP). The examples are illustrative of how single policy studies can be designed to use different approaches in the analysis: multiple streams approach to policy-making; a comparative hypothesis testing; and feminist institutional theory....

  10. Serial radionuclide quantitative function studies for evaluation of renal transplants

    International Nuclear Information System (INIS)

    Martin, D.C.; Hunter, J.L.; Lawton, M.B.; Berke, R.A.; Morton, M.E.

    1974-01-01

    A new method of assessing renal function following transplantation has been presented. The calculated rate of transfer to the kidney expressed as percent per minute, effective renal blood flow in milliliters per minute and the percentage of the dose in the urine at 20 minutes are calculated from data derived from a scintillation probe over the heart following a single injection of radiohippuran. These indices provide a means of interpreting serial determinations of renal function in states in which the more conventional parameters of renal function are not reliable. (U.S.)

  11. African Studies Monographs: Editorial Policies

    African Journals Online (AJOL)

    Focus and Scope. The African Studies Monographs is a serial that promotes research and scholarship on the African perspective worldwide. This includes matters of philosophy, history, literature, arts and culture, environment, gender, politics, administration crisis management, etc.

  12. The involvement of long-term serial-order memory in reading development: A longitudinal study.

    Science.gov (United States)

    Bogaerts, Louisa; Szmalec, Arnaud; De Maeyer, Marjolijn; Page, Mike P A; Duyck, Wouter

    2016-05-01

    Recent findings suggest that Hebb repetition learning-a paradigmatic example of long-term serial-order learning-is impaired in adults with dyslexia. The current study further investigated the link between serial-order learning and reading using a longitudinal developmental design. With this aim, verbal and visual Hebb repetition learning performance and reading skills were assessed in 96 Dutch-speaking children who we followed from first through second grade of primary school. We observed a positive association between order learning capacities and reading ability as well as weaker Hebb learning performance in early readers with poor reading skills even at the onset of reading instruction. Hebb learning further predicted individual differences in later (nonword) reading skills. Finally, Hebb learning was shown to explain a significant part of the variance in reading performance above and beyond phonological awareness. These findings highlight the role of serial-order memory in reading ability. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Serially cultured keratinocytes from human scalp hair follicles: a tool for cytogenetic studies.

    Science.gov (United States)

    Weterings, P J; Roelofs, H M; Jansen, B A; Vermorken, A J

    1983-01-01

    Keratinocytes originating from adult human hair follicles, the most convenient biopsy tissue, can be serially cultured using a combination of two techniques. Primary cultures are established using plucked scalp hair follicles and the bovine eye lens capsule as a growth substrate. Subsequently, cells from these cultures are serially cultivated in the presence of irradiated 3T3 cells as feeders. By this combination of techniques many keratinocytes can be generated from one single hair follicle. These cultures, appropriately treated with colchicine, can provide an adequate number of metaphases suitable for chromosome studies.

  14. FREQUENCY OF ANEUPLOID SPERMATOZOA STUDIED BY MULTICOLOR FISH IN SERIAL SEMEN SAMPLES

    Science.gov (United States)

    Frequency of aneuploid spermatozoa studied by multicolor FISH in serial semen samplesM. Vozdova1, S. D. Perreault2, O. Rezacova1, D. Zudova1 , Z. Zudova3, S. G. Selevan4, J. Rubes1,51Veterinary Research Institute, Brno, Czech Republic; 2U.S. Environmental Protection A...

  15. A serial qualitative interview study of infant feeding experiences: idealism meets realism

    Science.gov (United States)

    Craig, Leone C A; Britten, Jane; McInnes, Rhona M

    2012-01-01

    Objective To investigate the infant feeding experiences of women and their significant others from pregnancy until 6 months after birth to establish what would make a difference. Design Qualitative serial interview study. Setting Two health boards in Scotland. Participants 72 of 541 invited pregnant women volunteered. 220 interviews approximately every 4 weeks with 36 women, 26 partners, eight maternal mothers, one sister and two health professionals took place. Results The overarching theme was a clash between overt or covert infant feeding idealism and the reality experienced. This is manifest as pivotal points where families perceive that the only solution that will restore family well-being is to stop breast feeding or introduce solids. Immediate family well-being is the overriding goal rather than theoretical longer term health benefits. Feeding education is perceived as unrealistic, overly technical and rules based which can undermine women's confidence. Unanimously families would prefer the balance to shift away from antenatal theory towards more help immediately after birth and at 3–4 months when solids are being considered. Family-orientated interactive discussions are valued above breastfeeding-centred checklist style encounters. Conclusions Adopting idealistic global policy goals like exclusive breast feeding until 6 months as individual goals for women is unhelpful. More achievable incremental goals are recommended. Using a proactive family-centred narrative approach to feeding care might enable pivotal points to be anticipated and resolved. More attention to the diverse values, meanings and emotions around infant feeding within families could help to reconcile health ideals with reality. PMID:22422915

  16. Adapting Parcellation Schemes to Study Fetal Brain Connectivity in Serial Imaging Studies

    DEFF Research Database (Denmark)

    Cheng, Xi; Wilm, Jakob; Seshamani, Sharmishtaa

    2013-01-01

    A crucial step in studying brain connectivity is the definition of the Regions Of Interest (ROI's) which are considered as nodes of a network graph. These ROI's identified in structural imaging reflect consistent functional regions in the anatomies being compared. However in serial studies...... of the developing fetal brain such functional and associated structural markers are not consistently present over time. In this study we adapt two non-atlas based parcellation schemes to study the development of connectivity networks of a fetal monkey brain using Diffusion Weighted Imaging techniques. Results...... demonstrate that the fetal brain network exhibits small-world characteristics and a pattern of increased cluster coefficients and decreased global efficiency. These findings may provide a route to creating a new biomarker for healthy fetal brain development....

  17. Wandering carotid arteries: Reciprocating change between normal and retropharyngeal positions on serial CT studies

    Directory of Open Access Journals (Sweden)

    Akira Baba

    2017-12-01

    Full Text Available Positional change in the retropharyngeal carotid artery, a rare phenomenon over time, is even rarer in previous reports, and it is important to be aware of this before any neck surgical procedure. A woman in her 50s underwent an anterior maxillectomy for upper gingival cancer, without neck dissection. The patient had medical histories of diabetes mellitus and liver dysfunction, with unremarkable family histories. Serial neck contrast-enhanced computed tomography for detecting locoregional recurrence had been performed as a follow-up during 4 years. A radiological course of moving carotid arteries in serial computed tomography studies showed reciprocating positional changes (wandering between normal and retropharyngeal regions. There was no locoregional recurrence of the gingival cancer. This is the first case to describe a so-rare presentation of wandering carotid arteries. It is important for clinicians to be aware of a wandering carotid artery to avoid potentially fatal complications.

  18. Study on market policy

    International Nuclear Information System (INIS)

    2008-02-01

    In April 2007 the Dutch Minister of Economic Affairs promised the Lower House a study of the development of the public interests of quality, accessibility and efficiency after the introduction of market liberalization. In the debate on market liberalization in May 2007 the Minister complied with the Lower House?s request to include the consequences of the market liberalization operations on sectoral employment and labor conditions. This study addresses two questions: (1) Which developments occurred in the field of public interests quality, accessibility and efficiency and labor conditions since the introduction of market liberalization? and (2) What general findings and conclusions can be drawn from the implemented market liberalization policy in various sectors? What lessons can be learned for the future? Several sectors have been examined, including large energy users; renewable energy; energy market for medium users; energy (gas and electricity) [nl

  19. Combining confocal laser scanning microscopy with serial section reconstruction in the study of adult neurogenesis.

    Directory of Open Access Journals (Sweden)

    Federico eLuzzati

    2011-05-01

    Full Text Available Current advances in imaging techniques have extended the possibility of visualizing small structures within large volumes of both fixed and live specimens without sectioning. These techniques have contributed valuable information to study neuronal plasticity in the adult brain. However, technical limits still hamper the use of these approaches to investigate neurogenic regions located far from the ventricular surface such as parenchymal neurogenic niches, or the scattered neuroblasts induced by brain lesions. Here, we present a method to combine confocal laser scanning microscopy (CLSM and serial section reconstruction in order to reconstruct large volumes of brain tissue at cellular resolution. In this method a series of thick sections are imaged with CLSM and the resulting stacks of images are registered and 3D reconstructed. This approach is based on existing freeware software and can be performed on ordinary laboratory personal computers (PC. By using this technique we have investigated the morphology and spatial organization of a group of doublecortin (DCX+ neuroblasts located in the lateral striatum of the late post-natal guinea pig. The 3D study unravelled a complex network of long and poorly ramified cell processes, often fascicled and mostly oriented along the internal capsule fibre bundles. These data support CLSM serial section reconstruction as a reliable alternative to the whole mount approaches to analyze cyto-architectural features of adult germinative niches.

  20. Consistency of parametric registration in serial MRI studies of brain tumor progression

    International Nuclear Information System (INIS)

    Mang, Andreas; Buzug, Thorsten M.; Schnabel, Julia A.; Crum, William R.; Modat, Marc; Ourselin, Sebastien; Hawkes, David J.; Camara-Rey, Oscar; Palm, Christoph; Caseiras, Gisele Brasil; Jaeger, H.R.

    2008-01-01

    The consistency of parametric registration in multi-temporal magnetic resonance (MR) imaging studies was evaluated. Serial MRI scans of adult patients with a brain tumor (glioma) were aligned by parametric registration. The performance of low-order spatial alignment (6/9/12 degrees of freedom) of different 3D serial MR-weighted images is evaluated. A registration protocol for the alignment of all images to one reference coordinate system at baseline is presented. Registration results were evaluated for both, multimodal intra-timepoint and mono-modal multi-temporal registration. The latter case might present a challenge to automatic intensity-based registration algorithms due to ill-defined correspondences. The performance of our algorithm was assessed by testing the inverse registration consistency. Four different similarity measures were evaluated to assess consistency. Careful visual inspection suggests that images are well aligned, but their consistency may be imperfect. Sub-voxel inconsistency within the brain was found for allsimilarity measures used for parametric multi-temporal registration. T1-weighted images were most reliable for establishing spatial correspondence between different timepoints. The parametric registration algorithm is feasible for use in this application. The sub-voxel resolution mean displacement error of registration transformations demonstrates that the algorithm converges to an almost identical solution for forward and reverse registration. (orig.)

  1. Serial casting versus stretching technique to treat knee flexion contracture in children with spina bifida: a comparative study.

    Science.gov (United States)

    Al-Oraibi, S; Tariah, Hashem Abu; Alanazi, Abdullah

    2013-01-01

    Severe knee contractures that develop soon after muscle imbalance may not improve with stretching exercises and splinting. An alternative treatment is serial casting, which has been used to promote increased range of motion. The purpose of this study was to compare the effectiveness of using serial casting and passive stretching approaches to treat knee flexion contracture in children with spina bifida. In a pre/post randomized controlled study, ten participants were included in the serial casting group, while eight participants were included in the passive stretching intervention group. The degree of knee extension was measured at baseline, immediately after intervention, and at a one-year follow-up using a standard goniometer. Both groups showed significant improvements in the degree of flexion contracture at the post-treatment evaluation and the follow-up evaluation. The serial casting group showed significant improvements in knee flexion contracture at the post-treatment evaluation, t (9)=13.4, p casting group compared with passive stretching group in relation to the degree of flexion contracture were found at the immediate post-treatment evaluation, F(1, 15)=246, p=0.0001, and the one-year follow-up evaluation, F (1, 15)=51.5, p=0.0001. The outcomes of this study provide the first evidence that serial casting may be a useful intervention in treating knee flexion contracture in children with spina bifida. However, further investigations into serial casting, as well as investigations into the use of serial casting with other interventions, are warranted.

  2. Study of a mixed parallel and serial data transmission in trigger system of Beijing Spectrometer III

    International Nuclear Information System (INIS)

    Wang Ke; Yin Zejie; Liu Zhen'an; Zhao Dixin; Guo Ya'nan

    2005-01-01

    Serial optical fiber transmission technology will be used to transfer data from the detector electronics systems to the trigger system in the Beijing Spectrometer III. This technology has the advantages of cutting off the ground loops between the electronics systems and the trigger system, improving the system immunity to electro-magnetic interference and lengthening the transfer distance. Some important aspects of this technology are carefully studied, such as the bit-error-rate, error report, synchronization-back, delay skew of channels and phase stability. Design for single line self-synchronizing back is given, which makes the system more robust. The skew of channels is half a period. So the synchronous parallel data can be gotten if the rising of sample clock is set at the middle of the stable time of all deserialized data. This method can meet the requirement of BES III data transmission. (authors)

  3. A prospective study to investigate the role of serial serum mesothelin in monitoring mesothelioma.

    Science.gov (United States)

    de Fonseka, Duneesha; Arnold, David T; Stadon, Louise; Morley, Anna; Keenan, Emma; Darby, Michael; Armstrong, Lynne; Virgo, Paul; Maskell, Nick A

    2018-02-17

    Radiological monitoring of malignant pleural mesothelioma (MPM) using modified RECIST criteria is limited by low sensitivity and inter-observer variability. Serial serum mesothelin measurement has shown utility in the assessment of treatment response during chemotherapy but has never been assessed in the longer term follow up of patients. This is a single centre study of consecutive patients diagnosed with MPM who received chemotherapy or best supportive care (BSC). Serum mesothelin measurements with paired 6 monthly CT scans were performed following the completion of chemotherapy, or from baseline in the BSC group. Changes in mesothelin were correlated with radiological progression and overall survival. Forty-one patients with MPM were recruited and followed up for a minimum of 12 months (range 12-21 months). The majority of patients (n = 23) received chemotherapy with pemetrexed and cisplatin. Across the cohort a 10% rise in serum mesothelin could predict radiological progression with a sensitivity of 96% (IQR; 79-100) and specificity of 74% (IQR; 50-91). Sensitivity fell to 80% in sarcomatoid only disease. Patients with a rising mesothelin at 6 months had significantly worse overall survival (175 days) compared to stable/falling levels (448 days) (p = 0.003). This is the first study to assess serum mesothelin's ability to detect progression of MPM following chemotherapy or during BSC. A 10% rise in serum mesothelin level showed excellent sensitivity at predicting progressive disease. Mesothelin measurement has several advantages over serial CT imaging including reducing hospital visits and cost.

  4. Significant others, situations and infant feeding behaviour change processes: a serial qualitative interview study.

    Science.gov (United States)

    McInnes, Rhona J; Hoddinott, Pat; Britten, Jane; Darwent, Kirsty; Craig, Leone C A

    2013-05-16

    Exclusive breastfeeding until six months followed by the introduction of solids and continued breastfeeding is recommended by the World Health Organisation. The dominant approach to achieving this has been to educate and support women to start and continue breastfeeding rather than understanding behaviour change processes from a broader perspective. Serial qualitative interviews examined the influences of significant others on women's feeding behaviour. Thirty-six women and 37 nominated significant others participated in 220 interviews, conducted approximately four weekly from late pregnancy to six months after birth. Responses to summative structured questions at the end of each interview asking about significant influences on feeding decisions were compared and contrasted with formative semi-structured data within and between cases. Analysis focused on pivotal points where behaviour changed from exclusive breastfeeding to introducing formula, stopping breastfeeding or introducing solids. This enabled us to identify processes that decelerate or accelerate behaviour change and understand resolution processes afterwards. The dominant goal motivating behaviour change was family wellbeing, rather than exclusive breastfeeding. Rather than one type of significant other emerging as the key influence, there was a complex interplay between the self-baby dyad, significant others, situations and personal or vicarious feeding history. Following behaviour change women turned to those most likely to confirm or resolve their decisions and maintain their confidence as mothers. Applying ecological models of behaviour would enable health service organisation, practice, policy and research to focus on enhancing family efficacy and wellbeing, improving family-centred communication and increasing opportunities for health professionals to be a constructive influence around pivotal points when feeding behaviour changes. A paradigm shift is recommended away from the dominant approach of

  5. Serial MRI and MRS studies with unusual findings in Rasmussen's encephalitis

    International Nuclear Information System (INIS)

    Tuerkdogan-Soezueer, D.; Oezek, M.M.; Pamir, M.N.; Sav, A.; Dincer, A.

    2000-01-01

    Rasmussen's syndrome is characterized by intractable seizures and progressive neuropsychiatric deterioration secondary to unilateral cortical inflammation and tissue destruction. Diagnosis of Rasmussen's syndrome in the early phase depends mainly on the clinical features. Neuroimaging and histopathologic examinations may not be specific during this period. We report a case of Rasmussen's syndrome followed by serial MRI and magnetic resonance spectroscopy (MRS) studies over a 3- to 16-month period. A healthy 6-year-old boy presented with focal motor seizures. An MRI study demonstrated prominent enlargement and T2 hyperintensity of the left mesial temporal lobe and perisylvian region. This early finding evolved to volume loss and later progressive atrophy of the ipsilateral hemisphere when epilepsia partialis continua occurred. Being aware of those early MRI features in a patient with increasing frequency of focal motor seizures should suggest Rasmussen's syndrome. In addition, we found prominently increased myoinositol concentration in atrophic cortex which might reflect increased gliosis in the late period of the disease. (orig.)

  6. Serial MRI and MRS studies with unusual findings in Rasmussen's encephalitis

    Energy Technology Data Exchange (ETDEWEB)

    Tuerkdogan-Soezueer, D. [Department of Pediatric Neurology, Institute of Neurological Sciences, Marmara University, Istanbul (Turkey); Oezek, M.M.; Pamir, M.N. [Department of Neurosurgery, Institute of Neurological Sciences, Marmara University, Istanbul (Turkey); Sav, A. [Department of Pathology, Institute of Neurological Sciences, Marmara University, Istanbul (Turkey); Dincer, A. [Radyomar MR Center, Istanbul (Turkey)

    2000-06-01

    Rasmussen's syndrome is characterized by intractable seizures and progressive neuropsychiatric deterioration secondary to unilateral cortical inflammation and tissue destruction. Diagnosis of Rasmussen's syndrome in the early phase depends mainly on the clinical features. Neuroimaging and histopathologic examinations may not be specific during this period. We report a case of Rasmussen's syndrome followed by serial MRI and magnetic resonance spectroscopy (MRS) studies over a 3- to 16-month period. A healthy 6-year-old boy presented with focal motor seizures. An MRI study demonstrated prominent enlargement and T2 hyperintensity of the left mesial temporal lobe and perisylvian region. This early finding evolved to volume loss and later progressive atrophy of the ipsilateral hemisphere when epilepsia partialis continua occurred. Being aware of those early MRI features in a patient with increasing frequency of focal motor seizures should suggest Rasmussen's syndrome. In addition, we found prominently increased myoinositol concentration in atrophic cortex which might reflect increased gliosis in the late period of the disease. (orig.)

  7. Emotional noun processing: an ERP study with rapid serial visual presentation.

    Directory of Open Access Journals (Sweden)

    Shengnan Yi

    Full Text Available Reading is an important part of our daily life, and rapid responses to emotional words have received a great deal of research interest. Our study employed rapid serial visual presentation to detect the time course of emotional noun processing using event-related potentials. We performed a dual-task experiment, where subjects were required to judge whether a given number was odd or even, and the category into which each emotional noun fit. In terms of P1, we found that there was no negativity bias for emotional nouns. However, emotional nouns elicited larger amplitudes in the N170 component in the left hemisphere than did neutral nouns. This finding indicated that in later processing stages, emotional words can be discriminated from neutral words. Furthermore, positive, negative, and neutral words were different from each other in the late positive complex, indicating that in the third stage, even different emotions can be discerned. Thus, our results indicate that in a three-stage model the latter two stages are more stable and universal.

  8. Emotional noun processing: an ERP study with rapid serial visual presentation.

    Science.gov (United States)

    Yi, Shengnan; He, Weiqi; Zhan, Lei; Qi, Zhengyang; Zhu, Chuanlin; Luo, Wenbo; Li, Hong

    2015-01-01

    Reading is an important part of our daily life, and rapid responses to emotional words have received a great deal of research interest. Our study employed rapid serial visual presentation to detect the time course of emotional noun processing using event-related potentials. We performed a dual-task experiment, where subjects were required to judge whether a given number was odd or even, and the category into which each emotional noun fit. In terms of P1, we found that there was no negativity bias for emotional nouns. However, emotional nouns elicited larger amplitudes in the N170 component in the left hemisphere than did neutral nouns. This finding indicated that in later processing stages, emotional words can be discriminated from neutral words. Furthermore, positive, negative, and neutral words were different from each other in the late positive complex, indicating that in the third stage, even different emotions can be discerned. Thus, our results indicate that in a three-stage model the latter two stages are more stable and universal.

  9. The morphosyntax of verbs of motion in serial constructions: a crosslinguistic study in three signed languages

    NARCIS (Netherlands)

    Benedicto, E.; Cvejanov, S.; Quer, J.; Quer, J.F.

    2008-01-01

    This paper provides a comparative analysis of the structural properties of serial verb constructions (SVC) in three sign languages: LSA (Lengua de Señas Argentina, Argentinean Sign Language), LSC (Llengua de Signes Catalana, Catalan Sign Language) and ASL (American Sign Language). The paper presents

  10. Novel animal model for Achilles tendinopathy: Controlled experimental study of serial injections of collagenase in rabbits.

    Science.gov (United States)

    de Cesar Netto, Cesar; Godoy-Santos, Alexandre Leme; Augusto Pontin, Pedro; Natalino, Renato Jose Mendonça; Pereira, Cesar Augusto Martins; Lima, Francisco Diego de Oliveira; da Fonseca, Lucas Furtado; Staggers, Jackson Rucker; Cavinatto, Leonardo Muntada; Schon, Lew Charles; de Camargo, Olavo Pires; Fernandes, Túlio Diniz

    2018-01-01

    Our goal was to develop a novel technique for inducing Achilles tendinopathy in animal models which more accurately represents the progressive histological and biomechanical characteristic of chronic Achilles tendinopathy in humans. In this animal research study, forty-five rabbits were randomly assigned to three groups and given bilateral Achilles injections. Low dose (LD group) (n = 18) underwent a novel technique with three low-dose (0.1mg) injections of collagenase that were separated by two weeks, the high dose group (HD) (n = 18) underwent traditional single high-dose (0.3mg) injections, and the third group were controls (n = 9). Six rabbits were sacrificed from each experimental group (LD and HD) at 10, 12 and 16 weeks. Control animals were sacrificed after 16 weeks. Histological and biomechanical properties were then compared in all three groups. At 10 weeks, Bonar score and tendon cross sectional area was highest in HD group, with impaired biomechanical properties compared to LD group. At 12 weeks, Bonar score was higher in LD group, with similar biomechanical findings when compared to HD group. After 16 weeks, Bonar score was significantly increased for both LD group (11,8±2,28) and HD group (5,6±2,51), when compared to controls (2±0,76). LD group showed more pronounced histological and biomechanical findings, including cross sectional area of the tendon, Young's modulus, yield stress and ultimate tensile strength. In conclusion, Achilles tendinopathy in animal models that were induced by serial injections of low-dose collagenase showed more pronounced histological and biomechanical findings after 16 weeks than traditional techniques, mimicking better the progressive and chronic characteristic of the tendinopathy in humans.

  11. Coping Well with Advanced Cancer: A Serial Qualitative Interview Study with Patients and Family Carers

    Science.gov (United States)

    Roberts, Diane; Appleton, Lynda; Calman, Lynn; Large, Paul; Lloyd-Williams, Mari; Grande, Gunn

    2017-01-01

    Objectives To understand successful strategies used by people to cope well when living with advanced cancer; to explore how professionals can support effective coping strategies; to understand how to support development of effective coping strategies for patients and family carers. Design Qualitative serial (4–12 week intervals) interview study with people with advanced cancer and their informal carers followed by focus groups. The iterative design had a novel focus on positive coping strategies. Interview analysis focused on patients and carers as individuals and pairs, exploring multiple dimensions of their coping experiences. Focus group analysis explored strategies for intervention development. Participants 26 people with advanced (stage 3–4) breast, prostate, lung or colorectal cancer, or in receipt of palliative care, and 24 paired nominated informal/family carers. Setting Participants recruited through outpatient clinics at two tertiary cancer centres in Merseyside and Manchester, UK, between June 2012 and July 2013. Results 45 patient and 41 carer interviews were conducted plus 4 focus groups (16 participants). People with advanced cancer and their informal/family carers develop coping strategies which enable effective management of psychological wellbeing. People draw from pre-diagnosis coping strategies, but these develop through responding to the experience of living with advanced cancer. Strategies include being realistic, indulgence, support, and learning from others, which enabled participants to regain a sense of wellbeing after emotional challenge. Learning from peers emerged as particularly important in promoting psychological wellbeing through the development of effective ‘everyday’, non-clinical coping strategies. Conclusions Our findings challenge current models of providing psychological support for those with advanced cancer which focus on professional intervention. It is important to recognise, enable and support peoples’ own

  12. An Investigation of Selective College and University Libraries' Serial Arrangement.

    Science.gov (United States)

    Kesler, Elizabeth Gates; Teborek, Gay

    Data from a survey on serials arrangement procedures and policies at academic libraries was used by the University of Rhode Island (URI) Library in changing current serials policies. Ten libraries, four of which have similar serial holdings and user populations to URI, responded to a questionnaire. Information was obtained on classification versus…

  13. Serial changes of humor comprehension for four-frame comic Manga: an fMRI study.

    Science.gov (United States)

    Osaka, Mariko; Yaoi, Ken; Minamoto, Takehiro; Osaka, Naoyuki

    2014-07-25

    Serial changes of humor comprehension evoked by a well organized four-frame comic Manga were investigated by fMRI in each step of humor comprehension. The neural substrates underlying the amusing effects in response to funny and mixed order manga were compared. In accordance with the time course of the four frames, fMRI activations changed serially. Beginning with the second frame (development scene), activation of the temporo-parietal junction (TPJ) was observed, followed by activations in the temporal and frontal areas during viewing of the third frame (turn scene). For the fourth frame (punch line), strong increased activations were confirmed in the medial prefrontal cortex (MPFC) and cerebellum. Interestingly, distinguishable activation differences in the cerebellum between funny and non-funny conditions were also found for the fourth frame. These findings suggest that humor comprehension evokes activation that initiates in the TPJ and expands to the MPFC and cerebellum at the convergence level.

  14. A comparative study between South African serial killers and their American counterparts

    OpenAIRE

    2009-01-01

    M.A. This dissertation explores the similarities and differences between South African serial killers and their American counterparts. Seven male candidates, each having committed their reign of terror within the relevant time period, have been included. The candidates compared well in home environments, number of friendships, emotional maturity, abuse undergone, temperament, and anti-social behaviour. Differences were found in comparing family bonding, wealth and education. This dissertat...

  15. Clinical and anatomic pathology effects of serial blood sampling in rat toxicology studies, using conventional or microsampling methods.

    Science.gov (United States)

    Caron, Alexis; Lelong, Christine; Bartels, T; Dorchies, O; Gury, T; Chalier, Catherine; Benning, Véronique

    2015-08-01

    As a general practice in rodent toxicology studies, satellite animals are used for toxicokinetic determinations, because of the potential impact of serial blood sampling on toxicological endpoints. Besides toxicological and toxicokinetic determinations, blood samples obtained longitudinally from a same animal may be used for the assessment of additional parameters (e.g., metabolism, pharmacodynamics, safety biomarkers) to maximize information that can be deduced from rodents. We investigated whether removal of up to 6 × 200 μL of blood over 24h can be applied in GLP rat toxicology studies without affecting the scientific outcome. 8 week-old female rats (200-300 g) were dosed for up to 1 month with a standard vehicle and subjected or not (controls) to serial blood sampling for sham toxicokinetic/ancillary determinations, using miniaturized methods allowing collection of 6 × 50, 100 or 200 μL over 24h. In-life endpoints, clinical pathology parameters and histopathology of organs sensitive to blood volume reduction were evaluated at several time points after completion of sampling. In sampled rats, minimal and reversible changes in red blood cell mass (maximally 15%) and subtle variations in liver enzymes, fibrinogen and neutrophils were not associated with any organ/tissue macroscopic or microscopic correlate. Serial blood sampling (up to 6 × 200 μL over 24h) is compatible with the assessment of standard toxicity endpoints in adult rats. Copyright © 2015 Elsevier Inc. All rights reserved.

  16. Serial Changes of Tendon Histomorphology and Strain Elastography After Induced Achilles Tendinopathy in Rabbits: An In Vivo Study.

    Science.gov (United States)

    Ahn, Kyung-Sik; Lee, Nam Joon; Kang, Chang Ho; Lee, Young Hen; Jeon, Hae Jeong

    2017-04-01

    The purpose of this study was to investigate and compare the serial changes of morphology and strain in the early process of Achilles tendinopathy in a rabbit model. A total of 10 New Zealand white rabbits underwent ligation of one of their Achilles tendons to induce ischemic injury. Both inflamed and contralateral Achilles tendons were serially evaluated with 3 follow-ups: the first on days 3 to 5, the second on days 9 to 13, and the third and last follow-up on days 15 to 20 after surgery. During each examination, tendon thickness was measured and red, green, and blue pixel intensities of the elastogram were analyzed using color histogram analysis software. Differences between the inflamed and control group were compared. The mean thickness of the inflamed tendons increased during consecutive follow-ups and was significantly larger than that of control tendons (P tendons was also serially increased and was higher than that in the control tendons, indicating softening. However, the difference was significant only in the second and third follow-ups (P Tendon thickening and softening developed during the early process of Achilles tendinopathy in a rabbit model. Tendon softening may present later than thickening. © 2017 by the American Institute of Ultrasound in Medicine.

  17. Managing uncertainty in advanced liver disease: a qualitative, multiperspective, serial interview study.

    Science.gov (United States)

    Kimbell, Barbara; Boyd, Kirsty; Kendall, Marilyn; Iredale, John; Murray, Scott A

    2015-11-19

    To understand the experiences and support needs of people with advanced liver disease and those of their lay and professional carers to inform improvements in the supportive and palliative care of this rapidly growing but currently neglected patient group. Multiperspective, serial interviews. We conducted up to three qualitative in-depth interviews with each patient and lay carer over 12 months and single interviews with case-linked healthcare professionals. Data were analysed using grounded theory techniques. Patients with advanced liver disease of diverse aetiologies recruited from an inpatient hepatology ward, and their lay carers and case-linked healthcare professionals nominated by the patients. Primary and secondary care in South-East Scotland. 37 participants (15 patients, 11 lay and 11 professional carers) completed 51 individual and 13 joint patient-carer interviews. Nine patients died during the study. Uncertainty dominated experiences throughout the course of the illness, across patients' considerable physical, psychological, social and existential needs and affected patients, lay carers and professionals. This related to the nature of the condition, the unpredictability of physical deterioration and prognosis, poor communication and information-sharing, and complexities of care. The pervasive uncertainty also shaped patients' and lay carers' strategies for coping and impeded care planning. While patients' acute medical care was usually well coordinated, their ongoing care lacked structure and focus. Living, dying and caring in advanced liver disease is dominated by pervasive, enduring and universally shared uncertainty. In the face of high levels of multidimensional patient distress, professionals must acknowledge this uncertainty in constructive ways that value its contribution to the person's coping approach. Pervasive uncertainty makes anticipatory care planning in advanced liver disease challenging, but planning 'just in case' is vital to ensure

  18. Incidence of Dysphagia and Serial Videofluoroscopic Swallow Study Findings After Anterior Cervical Discectomy and Fusion: A Prospective Study.

    Science.gov (United States)

    Min, Yusun; Kim, Won-Seok; Kang, Sung Shik; Choi, Jin Man; Yeom, Jin S; Paik, Nam-Jong

    2016-05-01

    Prospective study. To prospectively assess the incidence of dysphagia and to present the serial changes of each finding in the videofluoroscopic swallow study (VFSS) after anterior cervical discectomy and fusion (ACDF). The reported incidence of dysphagia after ACDF has varied widely, and the serial changes of dysphagia using VFSS have not been clearly determined yet. Data of 47 patients preoperatively and at 1 week and 1 month postoperatively were used for the analyses. The Bazaz dysphagia score and VFSS were checked preoperatively and at 1 week and 1 month postoperatively. The presence of aspiration or penetration, amount of vallecular and pyriform sinus residues, functional dysphagia scale, temporal parameters of oral transit time, pharyngeal transit time, and pharyngeal delay time (PDT) were evaluated from the VFSS data. Incidences of dysphagia measured by the Bazaz dysphagia score were 83.0% at 1 week and 59.6% at 1 month after ACDF. Although the incidence of aspiration was 4.3% and the incidence of penetration was 36.2% at 1 week and 25.5% at 1 month after surgery, none of the patients had aspiration pneumonia. The number of patients with vallecular and pyriform sinus residues significantly increased after ACDF. Further, there were no statistically significant changes at all time points in terms of oral transit time, pharyngeal transit time, and pharyngeal delay time. Dysphagia is common until 1 month after ACDF. Although the incidence of aspiration or penetration in VFSS after ACDF was high, no patient had aspiration pneumonia, which may be because of the intact neurological swallowing mechanism. The typical pattern of dysphagia after ACDF included vallecular and pyriform sinuses filled with postswallow residue, which may result from soft tissue edema and weak constriction of pharyngeal muscles after ACDF.

  19. Serial MR imaging studies in enlarged endolymphatic duct and sac syndrome

    International Nuclear Information System (INIS)

    Naganawa, Shinji; Koshikawa, Tokiko; Fukatsu, Hiroshi; Ishigaki, Takeo; Nakashima, Tsutomu

    2002-01-01

    Large vestibular aqueduct syndrome (LVAS) is a congenital disorder characterized by progressive or fluctuating sensorineural hearing loss of unknown etiology. Serial MR examinations were performed before and after the development of hearing loss in two patients with LVAS. The signal and volume of the enlarged endolymphatic sac (EES) vary even in ears with stable hearing. In ears with fluctuating hearing, changes in EES signals were observed in only one of two patients. The finding that the EES volume and signal intensity vary dynamically independently of hearing is important for future research into the pathophysiology of hearing loss in this syndrome. (orig.)

  20. A comparative study of working memory: immediate serial spatial recall in baboons (Papio papio) and humans.

    Science.gov (United States)

    Fagot, Joël; De Lillo, Carlo

    2011-12-01

    Two experiments assessed if non-human primates can be meaningfully compared to humans in a non-verbal test of serial recall. A procedure was used that was derived from variations of the Corsi test, designed to test the effects of sequence structure and movement path length in humans. Two baboons were tested in Experiment 1. The monkeys showed several attributes of human serial recall. These included an easier recall of sequences with a shorter number of items and of sequences characterized by a shorter path length when the number of items was kept constant. However, the accuracy and speed of processing did not indicate that the monkeys were able to benefit from the spatiotemporal structure of sequences. Humans tested in Experiment 2 showed a quantitatively longer memory span, and, in contrast with monkeys, benefitted from sequence structure. The results are discussed in relation to differences in how human and non-human primates segment complex visual patterns. Copyright © 2011 Elsevier Ltd. All rights reserved.

  1. International study on energy policies

    International Nuclear Information System (INIS)

    Anon.

    2004-01-01

    A study, presented in September 2004 at the world energy council congress of Sydney (Australia) by the French agency of environment and energy mastery (Ademe) evaluates the energy efficiency policies and their impact in 63 countries, and in particular in the developing countries. It has permitted to identify the five most efficient measures about which case studies have been given to subject specialists for thorough analysis. Completed in July 2004, this triennial report has been carried out by the Ademe and the World energy council with the joint collaboration of the Latin American energy organization (Olade) and the Asia Pacific energy research centre (Aperc) under the coordination of Enerdata agency. This short article makes a brief summary of this presentation: energy efficiency at the global scale, transport sector, world power consumption and CO 2 emissions, evaluation of energy efficiency policies and measures (institutions and programmes, efficiency labels and standards for household appliances, innovative financing means, local information centers). (J.S.)

  2. Tracing policy movements: methods for studying learning and policy circulation

    OpenAIRE

    Wood, Astrid

    2016-01-01

    Policy flows are not quantifiable and calculating processes but part of the uneven movement of ideas and experiences that involves power and personalities. Processes of learning and policy circulation have thus proven difficult to study especially as the exchanges taking place between actors and localities rarely lead directly to uptake. This paper outlines a conceptual and methodological framework for conducting policy mobilities research by attending to the plethora of ordinary practices – ...

  3. Reliability of concentrations of organophosphate pesticide metabolites in serial urine specimens from pregnancy in the Generation R study

    Science.gov (United States)

    Spaan, Suzanne; Pronk, Anjoeka; Koch, Holger M.; Jusko, Todd A.; Jaddoe, Vincent W.V.; Shaw, Pamela A.; Tiemeier, Henning M.; Hofman, Albert; Pierik, Frank H.; Longnecker, Matthew P.

    2014-01-01

    The widespread use of organophosphate (OP) pesticides has resulted in ubiquitous exposure in humans, primarily through their diet. Exposure to OP pesticides may have adverse health effects, including neurobehavioral deficits in children. The optimal design of new studies requires data on the reliability of urinary measures of exposure. In the present study, urinary concentrations of six dialkyl phosphate (DAP) metabolites, the main urinary metabolites of OP pesticides, were determined in 120 pregnant women participating in the Generation R Study in Rotterdam. Intra-class correlation coefficients (ICCs) across serial urine specimens taken at 25 weeks of pregnancy were determined to assess reliability. Geometric mean total DAP metabolite concentrations were 229 (GSD 2.2), 240 (GSD 2.1), and 224 (GSD 2.2) nmol/g creatinine across the three periods of gestation. Metabolite concentrations from the serial urine specimens in general correlated moderately. The ICCs for the six DAP metabolites ranged from 0.14 to 0.38 (0.30 for total DAPs), indicating weak to moderate reliability. Although the DAP metabolite levels observed in this study are slightly higher and slightly more correlated than in previous studies, the low to moderate reliability indicates a high degree of within-person variability, which presents challenges for designing well-powered epidemiologic studies. PMID:25515376

  4. Muscle atrophy and metal-on-metal hip implants: a serial MRI study of 74 hips.

    Science.gov (United States)

    Berber, Reshid; Khoo, Michael; Cook, Erica; Guppy, Andrew; Hua, Jia; Miles, Jonathan; Carrington, Richard; Skinner, John; Hart, Alister

    2015-06-01

    Muscle atrophy is seen in patients with metal-on-metal (MOM) hip implants, probably because of inflammatory destruction of the musculo-tendon junction. However, like pseudotumors, it is unclear when atrophy occurs and whether it progresses with time. Our objective was to determine whether muscle atrophy associated with MOM hip implants progresses with time. We retrospectively reviewed 74 hips in 56 patients (32 of them women) using serial MRI. Median age was 59 (23-83) years. The median time post-implantation was 83 (35-142) months, and the median interval between scans was 11 months. Hip muscles were scored using the Pfirrmann system. The mean scores for muscle atrophy were compared between the first and second MRI scans. Blood cobalt and chromium concentrations were determined. The median blood cobalt was 6.84 (0.24-90) ppb and median chromium level was 4.42 (0.20-45) ppb. The median Oxford hip score was 34 (5-48). The change in the gluteus minimus mean atrophy score between first and second MRI was 0.12 (p = 0.002). Mean change in the gluteus medius posterior portion (unaffected by surgical approach) was 0.08 (p = 0.01) and mean change in the inferior portion was 0.10 (p = 0.05). Mean pseudotumor grade increased by 0.18 (p = 0.02). Worsening muscle atrophy and worsening pseudotumor grade occur over a 1-year period in a substantial proportion of patients with MOM hip implants. Serial MRI helps to identify those patients who are at risk of developing worsening soft-tissue pathology. These patients should be considered for revision surgery before irreversible muscle destruction occurs.

  5. A serial 4DCT study to quantify range variations in charged particle radiotherapy of thoracic cancers

    International Nuclear Information System (INIS)

    Mori, Shinichiro; Dong, Lei; Starkschall, George; Mohan, Radhe; Chen, George T.Y.

    2014-01-01

    Weekly serial 4DCT scans were acquired under free breathing conditions to assess water-equivalent path length (WEL) variations due to both intrafractional and interfractional changes in tissue thickness and density and to calculate proton dose distributions resulting from anatomical variations observed in serial 4DCT. A template of region of interests (ROIs) was defined on the anterior-posterior (AP) beam's eye view, and WEL measurements were made over these ROIs to quantify chest wall thickness variations. Interfractional proton dose distributions were calculated to assess changes in the expected dose distributions caused by range variations. Mean intrafractional chest wall WEL changes during respiration varied by: -4.1 mm (<-10.2 mm), -3.6 mm (<-7.1 mm), -3.2 mm (<-5.6 mm) and -2.5 mm (<-5.1 mm) during respiration in the ITV, upper, middle and lower lung regions, respectively. The mean interfractional chest wall WEL variation at Week 6 decreased by -4.0 mm (<-8.6 mm), -9.1 mm (<-17.9 mm), -9.4 mm (<-25.3 mm) and -4.5 mm (<-15.6 mm) in the ITV, upper, middle and lower lung regions, respectively. The variations were decomposed into anterior and posterior chest wall thickness changes. Dose overshoot beyond the target was observed when the initial boli was applied throughout the treatment course. This overshoot is due to chest wall thickness variations and target positional variations. The radiological path length can vary significantly during respiration as well as over the course of several weeks of charged particle therapy. Intrafractional/interfractional chest wall thickness changes can be a significant source of range variation in treatment of lung tumors with charged particle beams, resulting in dose distribution perturbations from the initial plan. Consideration of these range variations should be made in choosing the therapeutic charged particle beam range. (author)

  6. Bayesian approach to estimate AUC, partition coefficient and drug targeting index for studies with serial sacrifice design.

    Science.gov (United States)

    Wang, Tianli; Baron, Kyle; Zhong, Wei; Brundage, Richard; Elmquist, William

    2014-03-01

    The current study presents a Bayesian approach to non-compartmental analysis (NCA), which provides the accurate and precise estimate of AUC 0 (∞) and any AUC 0 (∞) -based NCA parameter or derivation. In order to assess the performance of the proposed method, 1,000 simulated datasets were generated in different scenarios. A Bayesian method was used to estimate the tissue and plasma AUC 0 (∞) s and the tissue-to-plasma AUC 0 (∞) ratio. The posterior medians and the coverage of 95% credible intervals for the true parameter values were examined. The method was applied to laboratory data from a mice brain distribution study with serial sacrifice design for illustration. Bayesian NCA approach is accurate and precise in point estimation of the AUC 0 (∞) and the partition coefficient under a serial sacrifice design. It also provides a consistently good variance estimate, even considering the variability of the data and the physiological structure of the pharmacokinetic model. The application in the case study obtained a physiologically reasonable posterior distribution of AUC, with a posterior median close to the value estimated by classic Bailer-type methods. This Bayesian NCA approach for sparse data analysis provides statistical inference on the variability of AUC 0 (∞) -based parameters such as partition coefficient and drug targeting index, so that the comparison of these parameters following destructive sampling becomes statistically feasible.

  7. Developments in Serials: 1977

    Science.gov (United States)

    James, John R.

    1978-01-01

    Discusses issues and developments relating to several aspects of serials, including economics and acquisitions; bibliographic control; automation; education; serials literature and bibliographies; and copyrights. A bibliography is included. (Author/MBR)

  8. Therapeutic modulation of the natural history of coronary atherosclerosis: lessons learned from serial imaging studies.

    Science.gov (United States)

    Andrews, Jordan; Puri, Rishi; Kataoka, Yu; Nicholls, Stephen J; Psaltis, Peter J

    2016-08-01

    Despite advances in risk prediction, preventive and therapeutic strategies, atherosclerotic cardiovascular disease remains a major public health challenge worldwide, carrying considerable morbidity, mortality and health economic burden. There continues to be a need to better understand the natural history of this disease to guide the development of more effective treatment, integral to which is the rapidly evolving field of coronary artery imaging. Various imaging modalities have been refined to enable detailed visualization of the pathological substrate of atherosclerosis, providing accurate and reproducible measures of coronary plaque burden and composition, including the presence of high-risk characteristics. The serial application of such techniques, including coronary computed tomography angiography (CTA), intravascular ultrasound (IVUS) and optical coherence tomography (OCT) have uncovered important insights into the progression of coronary plaque over time in patients with stable and unstable coronary artery disease (CAD), and its responsiveness to therapeutic interventions. Here we review the use of different imaging modalities for the surveillance of coronary atherosclerosis and the lessons they have provided about the modulation of CAD by both traditional and experimental therapies.

  9. A study of objective functions for organs with parallel and serial architecture

    International Nuclear Information System (INIS)

    Stavrev, P.V.; Stavreva, N.A.; Round, W.H.

    1997-01-01

    An objective function analysis when target volumes are deliberately enlarged to account for tumour mobility and consecutive uncertainty in the tumour position in external beam radiotherapy has been carried out. The dose distribution inside the tumour is assumed to have logarithmic dependence on the tumour cell density which assures an iso-local tumour control probability. The normal tissue immediately surrounding the tumour is irradiated homogeneously at a dose level equal to the dose D(R)) delivered at the edge of the tumour The normal tissue in the high dose field is modelled as being organized in identical functional subunits (FSUs) composed of a relatively large number of cells. Two types of organs - having serial and parallel architecture are considered. Implicit averaging over intrapatient normal tissue radiosensitivity variations is done. A function describing the normal tissue survival probability S 0 is constructed. The objective function is given as a product of the total tumour control probability (TCP) and the normal tissue survival probability S 0 . The values of the dose D(R)) which result in a maximum of the objective function are obtained for different combinations of tumour and normal tissue parameters, such as tumour and normal tissue radiosensitivities, number of cells constituting a normal tissue functional unit, total number of normal cells under high dose (D(R)) exposure and functional reserve for organs having parallel architecture. The corresponding TCP and S 0 values are computed and discussed. (authors)

  10. Decreasing Serial Cost Sharing

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Østerdal, Lars Peter

    The increasing serial cost sharing rule of Moulin and Shenker [Econometrica 60 (1992) 1009] and the decreasing serial rule of de Frutos [Journal of Economic Theory 79 (1998) 245] have attracted attention due to their intuitive appeal and striking incentive properties. An axiomatic characterization...... of the increasing serial rule was provided by Moulin and Shenker [Journal of Economic Theory 64 (1994) 178]. This paper gives an axiomatic characterization of the decreasing serial rule...

  11. Decreasing serial cost sharing

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Østerdal, Lars Peter Raahave

    2009-01-01

    The increasing serial cost sharing rule of Moulin and Shenker (Econometrica 60:1009-1037, 1992) and the decreasing serial rule of de Frutos (J Econ Theory 79:245-275, 1998) are known by their intuitive appeal and striking incentive properties. An axiomatic characterization of the increasing serial...... rule was provided by Moulin and Shenker (J Econ Theory 64:178-201, 1994). This paper gives an axiomatic characterization of the decreasing serial rule....

  12. Serial MR Imaging of Intramuscular Hematoma: Experimental Study in a Rat Model with the Pathologic Correlation

    Science.gov (United States)

    Lee, Yeon Soo; Kwon, Soon Tae; Kim, Jong Ok

    2011-01-01

    Objective We wanted to demonstrate the temporal changes of the magnetic resonance imaging (MRI) findings in experimentally-induced intramuscular hematomas in rats and to correlate these data with the concurrent pathologic observations. Materials and Methods Intramuscular hematoma was induced in 30 rats. The MR images were obtained at 1, 4, 7 and 10 days and at 2, 3, 4, 6 and 8 weeks after muscle injury. The characteristic serial MRI findings were evaluated and the relative signal intensities were calculated. Pathologic specimens were obtained at each time point. Results On the T1-weighted imaging (T1WI), the intramuscular hematomas exhibited isointensity compared to that of muscle or the development of a high signal intensity (SI) rim on day one after injury. The high SI persisted until eight weeks after injury. On the T2-weighted imaging (T2WI), the hematomas showed high SI or centrally low SI on day one after injury, and mainly high SI after four days. A dark signal rim was apparent after seven days, which was indicative of hemosiderin on the pathology. The gradient echo (GRE) imaging yielded dark signal intensities at all stages. Conclusion Unlike brain hematomas, experimentally-induced intramuscular hematomas show increased SI on both the T1WI and T2WI from the acute stage onward, and this is pathologically correlated with a rich blood supply and rapid healing response to injury in the muscle. On the T2WI and GRE imaging, high SI with a peripheral dark signal rim is apparent from seven days to the chronic stage. PMID:21228942

  13. Serial MR Imaging of Intramuscular Hematoma: Experimental Study in a Rat Model with the Pathologic Correlation

    International Nuclear Information System (INIS)

    Lee, Yeon Soo; Kim, Jong Ok; Choi, Eun Seok; Kwon, Soon Tae

    2011-01-01

    We wanted to demonstrate the temporal changes of the magnetic resonance imaging (MRI) findings in experimentally-induced intramuscular hematomas in rats and to correlate these data with the concurrent pathologic observations. Intramuscular hematoma was induced in 30 rats. The MR images were obtained at 1, 4, 7 and 10 days and at 2, 3, 4, 6 and 8 weeks after muscle injury. The characteristic serial MRI findings were evaluated and the relative signal intensities were calculated. Pathologic specimens were obtained at each time point. On the T1-weighted imaging (T1WI), the intramuscular hematomas exhibited isointensity compared to that of muscle or the development of a high signal intensity (SI) rim on day one after injury. The high SI persisted until eight weeks after injury. On the T2-weighted imaging (T2WI), the hematomas showed high SI or centrally low SI on day one after injury, and mainly high SI after four days. A dark signal rim was apparent after seven days, which was indicative of hemosiderin on the pathology. The gradient echo (GRE) imaging yielded dark signal intensities at all stages. Unlike brain hematomas, experimentally-induced intramuscular hematomas show increased SI on both the T1WI and T2WI from the acute stage onward, and this is pathologically correlated with a rich blood supply and rapid healing response to injury in the muscle. On the T2WI and GRE imaging, high SI with a peripheral dark signal rim is apparent from seven days to the chronic stage

  14. Multimodal imaging in the elastase-induced aneurysm model in rabbits: a comparative study using serial DSA, MRA and CTA

    International Nuclear Information System (INIS)

    Doerfler, A.; Becker, W.; Wanke, I.; Goericke, S.; Oezkan, N.; Forsting, M.

    2004-01-01

    Background and Purpose: The elastase-induced aneurysm model in rabbits has proved to be suitable for testing new endovascular occlusion devices. The purpose of this study was to evaluate different imaging modalities for the depiction of anatomy and size of elastase-induced aneurysms and for serial follow-up imaging. Materials and Methods: Elastase-induced aneurysms were created in eight Chinchilla bastard rabbits by endoluminal incubation of porcine elastase. Serial imaging was performed using intravenous DSA (IVDSA), contrast-enhanced MRA (CEMRA), and time-of-flight MRA (TOF) 14 days, 4 weeks and 3 months after aneurysm creation. Intraarterial DSA (IADSA) and CT angiography (CTA) were performed after 3 months. Aneurysm size and geometry (height H, width W, neck width N) were compared. Results: On IVDSA after two weeks mean aneurysm height was 6.2 mm (range 2.8-11.0 mm), mean aneurysm neck width was 2.7 mm (range 2.0-4.2 mm) and mean aneurysm neck width was 2.7 mm (range 2.0-4.2 mm). We did not observed any statistically significant change in aneurysm dimensions during follow-up at 4 weeks (CEMRA: H: 5.4, W: 2.4, N: 2.4; TOF: H: 5.7, W: 2.4, N: 2.7) and 3 months (CEMRA: H: 5.8, W: 2.6, N: 2.6; TOF: H: 6.9, W: 2.8, N: 3.0). Aneurysm dimensions could be best seen on IADSA (H: 6.2, W: 3.0, N: 2.7) with good correlation to CTA (r=0.94; H: 6.1, W: 2.8, N: 2.6), CE-MRA (r=0.92), and TOF (r=0.97). TOF was superior to CEMRA in delineating the aneurysm wall. Conclusions: Serial imaging using MRA, CTA or intravenous and intraarterial angiography is feasible in the elastase-induced aneurysm model. Contrast-enhanced MRA, TOF-MRA and CTA showed good correlation to IADSA and are all suitable for non-invasive pretherapeutic measurement of aneurysm size. (orig.) [de

  15. Dyslexic children show short-term memory deficits in phonological storage and serial rehearsal: an fMRI study.

    Science.gov (United States)

    Beneventi, Harald; Tønnessen, Finn Egil; Ersland, Lars

    2009-01-01

    Dyslexia is primarily associated with a phonological processing deficit. However, the clinical manifestation also includes a reduced verbal working memory (WM) span. It is unclear whether this WM impairment is caused by the phonological deficit or a distinct WM deficit. The main aim of this study was to investigate neuronal activation related to phonological storage and rehearsal of serial order in WM in a sample of 13-year-old dyslexic children compared with age-matched nondyslexic children. A sequential verbal WM task with two tasks was used. In the Letter Probe task, the probe consisted of a single letter and the judgment was for the presence or absence of that letter in the prior sequence of six letters. In the Sequence Probe (SP) task, the probe consisted of all six letters and the judgment was for a match of their serial order with the temporal order in the prior sequence. Group analyses as well as single-subject analysis were performed with the statistical parametric mapping software SPM2. In the Letter Probe task, the dyslexic readers showed reduced activation in the left precentral gyrus (BA6) compared to control group. In the Sequence Probe task, the dyslexic readers showed reduced activation in the prefrontal cortex and the superior parietal cortex (BA7) compared to the control subjects. Our findings suggest that a verbal WM impairment in dyslexia involves an extended neural network including the prefrontal cortex and the superior parietal cortex. Reduced activation in the left BA6 in both the Letter Probe and Sequence Probe tasks may be caused by a deficit in phonological processing. However, reduced bilateral activation in the BA7 in the Sequence Probe task only could indicate a distinct working memory deficit in dyslexia associated with temporal order processing.

  16. Serial killers with military experience: applying learning theory to serial murder.

    Science.gov (United States)

    Castle, Tammy; Hensley, Christopher

    2002-08-01

    Scholars have endeavored to study the motivation and causality behind serial murder by researching biological, psychological, and sociological variables. Some of these studies have provided support for the relationship between these variables and serial murder. However, the study of serial murder continues to be an exploratory rather than explanatory research topic. This article examines the possible link between serial killers and military service. Citing previous research using social learning theory for the study of murder, this article explores how potential serial killers learn to reinforce violence, aggression, and murder in military boot camps. As with other variables considered in serial killer research, military experience alone cannot account for all cases of serial murder. Future research should continue to examine this possible link.

  17. Theories in Social Policy and Development Studies

    DEFF Research Database (Denmark)

    Schmidt, Johannes Dragsbæk

    Theories in Social Policy and Development Studies Presentation for the PhD Seminar - Theories, Concepts and Methods in Development Studies and Sociology......Theories in Social Policy and Development Studies Presentation for the PhD Seminar - Theories, Concepts and Methods in Development Studies and Sociology...

  18. Criminal psychological profiling of serial arson crimes.

    Science.gov (United States)

    Kocsis, Richard N; Cooksey, Ray W

    2002-12-01

    The practice of criminal psychological profiling is frequently cited as being applicable to serial arson crimes. Despite this claim, there does not appear to be any empirical research that examines serial arson offence behaviors in the context of profiling. This study seeks to develop an empirical model of serial arsonist behaviors that can be systematically associated with probable offender characteristics. Analysis has produced a model of offence behaviors that identify four discrete behavior patterns, all of which share a constellation of common nondiscriminatory behaviors. The inherent behavioral themes of each of these patterns are explored with discussion of their broader implications for our understanding of serial arson and directions for future research.

  19. A Study on the Nuclear Technology Policy

    International Nuclear Information System (INIS)

    Oh, K. B.; Lee, K. S.; Chung, W. S.; Lee, T. J.; Yun, S. W.; Jeong, I.; Lee, J. H.

    2007-02-01

    The objective of the study was to make policy-proposals for enhancing the effectiveness and efficiency of national nuclear technology R and D programs. To do this, environmental changes of international nuclear energy policy and trends of nuclear technology development were surveyed and analyzed. This Study analyzed trends of nuclear technology policies and developed the nuclear energy R and D innovation strategy in a viewpoint of analyzing the changes in the global policy environment associated with nuclear technology development and development of national nuclear R and D strategy

  20. A study on the nuclear technology policy

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Maeng Ho; Ham, C. H.; Kim, H. J.; Chung, W. S.; Lee, T. J.; Lee, B. O.; Yun, S. W.; Choi, Y. M.; Eom, T. Y

    1998-01-01

    This study analyzed the major issues as the research activities for the support of establishment and implementation of national policy. The analyses were focused on the recommendations of the responsive direction of national policy in positive and effective manners in accordance with the changes of international nuclear affairs. This study also analyzed the creation of environmental foundation for effective implementation of the national policy and national R and D investment such as securing national consensus and openings of policy information to the public. The major results of the role and position of nuclear policy, trends of nuclear policy and nuclear R and D activities of USA, France, Japan, Asian developing countries etc. and international trends of small- and medium-sized reactor as well as spin-offs of nuclear R and D activities, were analyzed. (author). 66 refs., 27 tabs., 15 figs

  1. Seni Sastra, Teater, dan Film dalam Konteks Perkotaan: Industrialisasi dan Urbanisme (Studi Kasus Serial Sinetron Film ”Intan”

    Directory of Open Access Journals (Sweden)

    Soediro Satoto

    2010-06-01

    Full Text Available Tulisan ini bertujuan memaparkan korelasi antara produksi seni sastra, seni teate, dan film serta menjelaskan keterkaitan yang erat antara urbanisasi, industrialisasi, dan urbanisme dengan perkembangan iptek dan seni, termasuk seni sastra, seni drama/teater, dan seni film/sinetron. Seirama dengan dinamika proses globalisasi di segala bidang, termasuk budaya dan seni, fenomena tersebut akan berdampak pada proses akulturasi lintas/silang budaya, perge- seran dan atau perubahan tata nilai dan identitas budaya bangsa. Akankah muncul identitas bu- daya ’baru’ (sebut yang khas ’urban’ dengan cara mengesampingkan atau membuang jauh-jauh identitas budaya ’lama’ (sebut tradisional yang dianggap sudah ketinggalan zaman? Bagaimana sepantasnya ’masyarakat sastra, teater, dan film’ menyikapi fenomena-fenomena tersebut secara kritis, realistis, dinamis, dan arif? Serial Sinetron Film “Intan” dalam makalah ini diambil seba- gai studi kasus karena rating-nya yang relatif konstan tertinggi jika dibandingkan dengan serial sinetron film lainnya di media yang sama dalam kurun waktu yang sama. Abstract: This paper is aimed to describe correlation between literary, theater, and film art production and explain the strong interrelatedness between urbanization, industrialization, and urbanism by the development of science technology and art, including literary art, drama/theater art, and film/sinetron art. Along with the dynamic of globalization process in all aspects, including culture and art (literary, theater, and film art in this case, the phenomena will have influences to cross/inter-cultural acculturation process, shift and/or change in a nation’s cultural identity and values. Will a ‘new’ (call it urban cultural identity emerge by putting aside or getting rid of the ‘old’ cultural identity (call it traditional which is regarded as old fashion? How should a ‘literary, theater, and film community’ behave critically, realistically

  2. Image-based dose planning of intracavitary brachytherapy: registration of serial-imaging studies using deformable anatomic templates

    International Nuclear Information System (INIS)

    Christensen, Gary E.; Carlson, Blake; Chao, K.S. Clifford; Yin Pen; Grigsby, Perry W.; Nguyen, Kim; Dempsey, James F; Lerma, Fritz A.; Bae, Kyongtae T.; Vannier, Michael W.; Williamson, Jeffrey F.

    2001-01-01

    Purpose: To demonstrate that high-dimensional voxel-to-voxel transformations, derived from continuum mechanics models of the underlying pelvic tissues, can be used to register computed tomography (CT) serial examinations into a single anatomic frame of reference for cumulative dose calculations. Methods and Materials: Three patients with locally advanced cervix cancer were treated with CT-compatible intracavitary (ICT) applicators. Each patient underwent five volumetric CT examinations: before initiating treatment, and immediately before and after the first and second ICT insertions, respectively. Each serial examination was rigidly registered to the patient's first ICT examination by aligning the bony anatomy. Detailed nonrigid alignment for organs (or targets) of interest was subsequently achieved by deforming the CT exams as a viscous-fluid, described by the Navier-Stokes equation, until the coincidence with the corresponding targets on CT image was maximized. In cases where ICT insertion induced very large and topologically complex rearrangements of pelvic organs, e.g., extreme uterine canal reorientation following tandem insertion, a viscous-fluid-landmark transformation was used to produce an initial registration. Results: For all three patients, reasonable registrations for organs (or targets) of interest were achieved. Fluid-landmark initialization was required in 4 of the 11 registrations. Relative to the best rigid bony landmark alignment, the viscous-fluid registration resulted in average soft-tissue displacements from 2.8 to 28.1 mm, and improved organ coincidence from the range of 5.2% to 72.2% to the range of 90.6% to 100%. Compared to the viscous-fluid transformation, global registration of bony anatomy mismatched 5% or more of the contoured organ volumes by 15-25 mm. Conclusion: Pelvic soft-tissue structures undergo large deformations and displacements during the external-beam and multiple-ICT course of radiation therapy for locally advanced cervix

  3. The contribution of short-term memory for serial order to early reading acquisition: evidence from a longitudinal study.

    Science.gov (United States)

    Martinez Perez, Trecy; Majerus, Steve; Poncelet, Martine

    2012-04-01

    Early reading acquisition skills have been linked to verbal short-term memory (STM) capacity. However, the nature of this relationship remains controversial because verbal STM, like reading acquisition, depends on the complexity of underlying phonological processing skills. This longitudinal study addressed the relation between STM and reading decoding acquisition by distinguishing between STM for item information and STM for order information based on recent studies showing that STM for item information, but not STM for order information, recruits underlying phonological representations. If there is a specific link between STM and reading decoding acquisition, STM for order information should be an independent predictor of reading decoding acquisition. Tasks maximizing STM for serial order or item information, measures of phonological abilities, and reading tests were administered to children followed from kindergarten through first grade. We observed that order STM capacity, but not item STM capacity, predicted independent variance in reading decoding abilities 1 year later. These results highlight the specific role of STM for order in reading decoding acquisition and argue for a causal role of order STM capacity in reading acquisition. Mechanisms relating STM for order information and reading acquisition are discussed. Copyright © 2011 Elsevier Inc. All rights reserved.

  4. Global gray matter changes in posterior cortical atrophy: A serial imaging study

    NARCIS (Netherlands)

    Lehmann, M.; Barnes, J.; Ridgway, G.R.; Ryan, N.S.; Warrington, E.K.; Crutch, S.J.; Fox, N.C.

    2012-01-01

    Background: Posterior cortical atrophy (PCA) is a neurodegenerative condition predominantly associated with Alzheimer's disease (AD) pathology. Cross-sectional imaging studies have shown different atrophy patterns in PCA patients compared with typical amnestic Alzheimer's disease (tAD) patients,

  5. Mechanisms of recovery from aphasia: evidence from serial xenon 133 cerebral blood flow studies

    International Nuclear Information System (INIS)

    Knopman, D.S.; Rubens, A.B.; Selnes, O.A.; Klassen, A.C.; Meyer, M.W.

    1984-01-01

    In 21 patients who suffered aphasia resulting from left hemisphere ischemic infarction, the xenon 133 inhalation cerebral blood flow technique was used to measure cerebral blood flow within 3 months and 5 to 12 months after stroke. In addition to baseline measurements, cerebral blood flow measurements were also carried out while the patients were performing purposeful listening. In patients with incomplete recovery of comprehension and left posterior temporal-inferior parietal lesions, greater cerebral blood flow occurred with listening in the right inferior frontal region in the late studies than in the early studies. In patients with nearly complete recovery of comprehension and without left posterior temporal-inferior parietal lesions, early listening studies showed diffuse right hemisphere increases in cerebral blood flow. Later listening studies in this latter patient group showed greater cerebral blood flow in the left posterior temporal-inferior parietal region. The study provides evidence for participation of the right hemisphere in language comprehension in recovering aphasics, and for later return of function in left hemisphere regions that may have been functionally impaired early during recovery

  6. Serial Discourse, Studying the Police Series Audience on French Television Website

    Directory of Open Access Journals (Sweden)

    Céline MASONI LACROIX

    2011-01-01

    Full Text Available Comments posted on french television websites about police series were studied in their discursive function in order to question the continental dichotomy between popular and scholar culture. Rereading produces, creates cultural practices. This article aims at opening a space for discourse, a space where cultural industry, reception and practices collide.

  7. Serial studies of cerebral blood flow using 99Tcm-HMPAO

    DEFF Research Database (Denmark)

    Andersen, A R; Friberg, H; Lassen, N A

    1987-01-01

    -HMPAO was measured after i.v. injection. High resolution (HR) and low resolution (LR) studies were performed yielding a resolution of 6 to 10 mm (HR) and 15 to 20 (LR). 99Tcm-HMPAO images showed close resemblance to xenon-133 CBF tomograms. Only about 20% of the (decay corrected) brain counts were lost during...

  8. Marijuana: A Study of State Policies & Penalties.

    Science.gov (United States)

    Peat, Marwick, Mitchell and Co., Columbia, MD.

    This study is a comprehensive analysis of issues concerning marijuana that are of importance to state policy makers. It reviews the medical, legal, and historical dimensions of marijuana use and examines the range of policy approaches toward marijuana possession and use which state officials have considered. Attention is directed to the experience…

  9. [A study of growth and malignancy grading of stomach and colorectal cancers by serial serum carcinoembryonic antigen levels analysis].

    Science.gov (United States)

    Umehara, Y; Miyahara, T; Yoshida, M; Isobe, S; Oba, N; Harada, Y

    1990-06-01

    Changes in serum CEA levels were analyzed on a time-course basis in 33 patients with stomach cancer and 20 patients with colorectal cancer. A linear relationship between log CEA and time could be evaluated and individual CEA doubling time (CEA D.T.) was calculated. The results obtained are as follows. 1) The CEA D.T. was not constant from the onset of the disease to death in stomach cancer and colorectal cancer. 2) The CEA D.T. was distributed widely with 5 to 140 days in stomach cancer and 8 to 134 days in colorectal cancer. It tended to be shortened at the terminal stage in both tumors. 3) In terms of age, sex and histology, the CEA D.T. tended to be short in the young, female and poorly differentiated cancer. These background appeared to have an influence on the growth of tumor. 4) The CEA D.T. was well correlated with the period of survival of the patients with gastric cancer (r = 0.636, p less than 0.001). The analysis of serial CEA levels on a time-course basis is considered useful in studying the relationship between tumor-bearing hosts and malignancy of the tumor.

  10. Diastolic left ventricular function in preterm infants with a patent ductus arteriosus: a serial Doppler echocardiography study.

    Science.gov (United States)

    Schmitz, Lothar; Stiller, Brigitte; Koch, Heike; Koehne, Petra; Lange, Peter

    2004-02-01

    In very low birth weight neonates, a left-to-right shunt via persistent ductus arteriosus (PDA) may interact with diastolic left ventricular function, but specific changes of Doppler parameters have yet to be reported. In a serial transmitral Doppler study, we investigated the impact of a PDA on diastolic function parameters. Twenty-two patients with and without PDA were examined on day 3.8+/-1 and day 14+/-2 after birth. By the first examination, 13 out of 22 patients had a PDA; by the second examination, the number was still 8 out of 22. Peak early and atrial flow velocities (44.8+/-15 and 50.1+/-13 cm/s, respectively) were higher (pclosure of the PDA. When premature infants with a PDA experience a preload challenge, early and atrial peak velocities increase and IVRT shortens significantly. This coincidence of elevated transvalvular pressure differences and decreased IVRT in neonates with immature diastolic function can best be explained as a result of left atrial pressure elevation. Consequently, pulmonary venous pressure must be elevated, with its inherent effect on pulmonary capillary physiology. Thus, the monitoring of left ventricular diastolic function adds significant information to the care of preterm infants with a PDA.

  11. Ongoing studies for the control system of a serially powered ATLAS pixel detector at the HL-LHC

    International Nuclear Information System (INIS)

    Kersten, S.; Püllen, L.; Zeitnitz, C.

    2016-01-01

    In terms of the phase-2 upgrade of the ATLAS detector, the entire inner tracker (ITk) of ATLAS will be replaced. This includes the pixel detector and the corresponding detector control system (DCS). The current baseline is a serial powering scheme of the detector modules. Therefore a new detector control system is being developed with emphasis on the supervision of serially powered modules. Previous chips had been designed to test the radiation hardness of the technology and the implementation of the modified I2C as well as the implementation of the logic of the CAN protocol. This included tests with triple redundant registers. The described chip is focusing on the implementation in a serial powering scheme. It was designed for laboratory tests, aiming for the proof of principle. The concept of the DCS for ATLAS pixel after the phase-2 upgrade is presented as well as the status of development including tests with the prototype ASIC

  12. Recovery from distal ulnar motor conduction block injury: serial EMG studies.

    Science.gov (United States)

    Montoya, Liliana; Felice, Kevin J

    2002-07-01

    Acute conduction block injuries often result from nerve compression or trauma. The temporal pattern of clinical, electrophysiologic, and histopathologic changes following these injuries has been extensively studied in experimental animal models but not in humans. Our recent evaluation of a young man with an injury to the deep motor branch of the ulnar nerve following nerve compression from weightlifting exercises provided the opportunity to follow the course and recovery of a severe conduction block injury with sequential nerve conduction studies. The conduction block slowly and completely resolved, as did the clinical deficit, over a 14-week period. The reduction in conduction block occurred at a linear rate of -6.1% per week. Copyright 2002 Wiley Periodicals, Inc.

  13. Changing incidence of diverticular disease of the colon in Korea : a serial radiologic study (report III)

    Energy Technology Data Exchange (ETDEWEB)

    Kwoen, Young Teck; Han, Sung Il; Chung, Soo Kyo; Bahk, Yong Whee [Catholic University Medical College, Seoul (Korea, Republic of)

    1988-10-15

    Diverticular disease of the colon (DDC), the most common affliction in developed countries, increases in incidence. It is an acquired disease where overactivity of smooth muscle of the colon causes mucosa and sub mucosa to herniate through the muscle layer of the bowel. Starting from 1964, we have periodically carried out radiologic survey to acertain the tendency of DDC to gradually increase in the Koreans. Initially Kim reported the incidence to be 0.2% in 1964 but the incidence in 1979 increased to 2.5% as reported by Chung et al. As the third survey on the series of the study on DDC, we have recently reviewed 1,859 consecutive new cases of double contrast barium enemas performed at the department of radiology, Kangnam St. Mary's Hospital, Catholic University Medical College during the 5 year's period from Feb. 1983 to May 1987. The results were as follows. 1. The present study revealed an incidence 6.0% of DDC, 7.2% in male and 5.0% in female. 2. The distribution of diverticular was 37.0% in cecum, 39.0% in ascending colon, 13.6% in transverse colon, 6.2% in descending colon, 3.7% in sigmoid colon. 3. The mean number of diverticular was 5. 4. The average age of patients with DDC was 50.5 years. From the present study, it has emerged that the diverticular disease of the colon in the Koreans is definitely on gradual increase with a significant change in the site of predominant involvement from the right to the left colon.

  14. Changing incidence of diverticular disease of the colon in Korea : a serial radiologic study (report III)

    International Nuclear Information System (INIS)

    Kwoen, Young Teck; Han, Sung Il; Chung, Soo Kyo; Bahk, Yong Whee

    1988-01-01

    Diverticular disease of the colon (DDC), the most common affliction in developed countries, increases in incidence. It is an acquired disease where overactivity of smooth muscle of the colon causes mucosa and sub mucosa to herniate through the muscle layer of the bowel. Starting from 1964, we have periodically carried out radiologic survey to acertain the tendency of DDC to gradually increase in the Koreans. Initially Kim reported the incidence to be 0.2% in 1964 but the incidence in 1979 increased to 2.5% as reported by Chung et al. As the third survey on the series of the study on DDC, we have recently reviewed 1,859 consecutive new cases of double contrast barium enemas performed at the department of radiology, Kangnam St. Mary's Hospital, Catholic University Medical College during the 5 year's period from Feb. 1983 to May 1987. The results were as follows. 1. The present study revealed an incidence 6.0% of DDC, 7.2% in male and 5.0% in female. 2. The distribution of diverticular was 37.0% in cecum, 39.0% in ascending colon, 13.6% in transverse colon, 6.2% in descending colon, 3.7% in sigmoid colon. 3. The mean number of diverticular was 5. 4. The average age of patients with DDC was 50.5 years. From the present study, it has emerged that the diverticular disease of the colon in the Koreans is definitely on gradual increase with a significant change in the site of predominant involvement from the right to the left colon.

  15. Effect of lesion site on serial position during list learning: a study with the CVLT.

    Science.gov (United States)

    Albuquerque, Luisa; Loureiro, Clara; Martins, Isabel Pavao

    2008-07-01

    Successful learning of supraspan word lists such as the California Verbal Learning Test (CVLT) relies more on clustering strategies than rote learning, subserved by the frontal and temporal lobes. The authors studied the effect of word sequence in CVLT learning, in 15 patients with frontal (FLL) and 15 temporal (TLL) lesions, and 33 controls. Experimental measures were: number of clusters, number of first (FI), middle (MI) and last items (LI), in learning trials and in total immediate recall. FLL disclosed significantly lower FI along learning. Clusters were similar among groups. This difficulty is discussed according to the role of frontal lobes in learning and memory.

  16. Impacts of a national strategy to reduce population salt intake in England: serial cross sectional study.

    Science.gov (United States)

    Millett, Christopher; Laverty, Anthony A; Stylianou, Neophytos; Bibbins-Domingo, Kirsten; Pape, Utz J

    2012-01-01

    The UK introduced an ambitious national strategy to reduce population levels of salt intake in 2003. The aim of this study was to evaluate the impact of this strategy on salt intake in England, including potential effects on health inequalities. Secondary analysis of data from the Health Survey for England. Our main outcome measure was trends in estimated daily salt intake from 2003-2007, as measured by spot urine. Secondary outcome measures were knowledge of government guidance and voluntary use of salt in food preparation over this time period. There were significant reductions in salt intake between 2003 and 2007 (-0.175 grams per day per year, pprofessional; 64.9% v 71.0% AOR 0.76 95% CI 0.58-0.99). Self reported use of salt added at the table reduced significantly during the study period (56.5% to 40.2% pcooking (white 42.8%, black 74.1%, south Asian 88.3%) and those from lower social class groups (unskilled manual 46.6%, professional 35.2%) were more likely to add salt at the table. The introduction a national salt reduction strategy was associated with uniform but modest reductions in salt intake in England, although it is not clear precisely which aspects of the strategy contributed to this. Knowledge of government guidance was lower and voluntary salt use and total salt intake was higher among occupational and ethnic groups at greatest risk of cardiovascular disease.

  17. Impacts of a national strategy to reduce population salt intake in England: serial cross sectional study.

    Directory of Open Access Journals (Sweden)

    Christopher Millett

    Full Text Available BACKGROUND: The UK introduced an ambitious national strategy to reduce population levels of salt intake in 2003. The aim of this study was to evaluate the impact of this strategy on salt intake in England, including potential effects on health inequalities. METHODS: Secondary analysis of data from the Health Survey for England. Our main outcome measure was trends in estimated daily salt intake from 2003-2007, as measured by spot urine. Secondary outcome measures were knowledge of government guidance and voluntary use of salt in food preparation over this time period. RESULTS: There were significant reductions in salt intake between 2003 and 2007 (-0.175 grams per day per year, p<0.001. Intake decreased uniformly across all other groups but remained significantly higher in younger persons, men, ethnic minorities and lower social class groups and those without hypertension in 2007. Awareness of government guidance on salt use was lowest in those groups with the highest intake (semi-skilled manual v professional; 64.9% v 71.0% AOR 0.76 95% CI 0.58-0.99. Self reported use of salt added at the table reduced significantly during the study period (56.5% to 40.2% p<0.001. Respondents from ethnic minority groups remained significantly more likely to add salt during cooking (white 42.8%, black 74.1%, south Asian 88.3% and those from lower social class groups (unskilled manual 46.6%, professional 35.2% were more likely to add salt at the table. CONCLUSIONS: The introduction a national salt reduction strategy was associated with uniform but modest reductions in salt intake in England, although it is not clear precisely which aspects of the strategy contributed to this. Knowledge of government guidance was lower and voluntary salt use and total salt intake was higher among occupational and ethnic groups at greatest risk of cardiovascular disease.

  18. Studies of serial serum electrophoretic pattern for prognosis in various cancer patients during irradiation

    International Nuclear Information System (INIS)

    Ra, Woo Youn; Woo, Won Hyung

    1971-01-01

    During the period from June. 1969 to Dec. 1970, the serum protein electrophoretic patterns of 44 cases of various cancer patients have been studied to determine the alterations in serum protein fractions in patients who were responding to irradiation or those failing. The serum electrophoretic pattern could be observed as an indicator of prognosis or radiosensitivity. A blood sample was obtained prior to any treatment and the follow up sampling was performed 2 times during radiation therapy. Serum total protein was determined by the method of Wolfson and serum electrophoresis was carried out by using Spinoco Model R B electrophoresis system. The results were following: Seven cases out of cases of cervical cancer responding favorably to radiotherapy showed decreased in Alpha-2 globulin fraction were increased. A case whose third time serum electrophoretic pattern showed multiple myeloma type died 5 months after radiotherapy with bone metastasis. Four cases out of 9 cases of favorably responded breast cancer patients showed decreased in Alpha-2 globulin foraction compared with 2 cases of unfavorable response showed increased in Alpha-2 globulin fraction

  19. Studies of serial serum electrophoretic pattern for prognosis in various cancer patients during irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Ra, Woo Youn; Woo, Won Hyung [Kyungpook National University School of Medicine, Taegu (Korea, Republic of)

    1971-10-15

    During the period from June. 1969 to Dec. 1970, the serum protein electrophoretic patterns of 44 cases of various cancer patients have been studied to determine the alterations in serum protein fractions in patients who were responding to irradiation or those failing. The serum electrophoretic pattern could be observed as an indicator of prognosis or radiosensitivity. A blood sample was obtained prior to any treatment and the follow up sampling was performed 2 times during radiation therapy. Serum total protein was determined by the method of Wolfson and serum electrophoresis was carried out by using Spinoco Model R B electrophoresis system. The results were following: Seven cases out of cases of cervical cancer responding favorably to radiotherapy showed decreased in Alpha-2 globulin fraction were increased. A case whose third time serum electrophoretic pattern showed multiple myeloma type died 5 months after radiotherapy with bone metastasis. Four cases out of 9 cases of favorably responded breast cancer patients showed decreased in Alpha-2 globulin foraction compared with 2 cases of unfavorable response showed increased in Alpha-2 globulin fraction.

  20. Is the ultimobranchial body a reality or myth: a study using serial sections of human embryos.

    Science.gov (United States)

    Honkura, Yohei; Yamamoto, Masahito; Yoshimoto, Toshihito; Rodriguez-Vazquez, Jose Francisco; Murakami, Gen; Katori, Yukio; Abe, Shin-Ichi

    2016-01-01

    Reported morphologies of the ultimobranchial body had varied between researchers: a cluster of mitotic cells, a duct-like structure and a rosette-like cell mass. To clarify the true morphology, we studied tilted horizontal sections of 20 human embryos (crown-rump length 5-18 mm; 4-6 weeks). The sections displayed a ladder-like arrangement of the second to fourth endodermal pouches and, in 5 early embryos we found the fifth pouch attached to the fifth ectodermal groove near the fourth pharyngeal arch artery. The bilateral fifth pharyngeal pouches protruded anterolaterally to form a U-shaped lumen surrounding the arytenoid swelling. The third to fifth pouches were each characterized by a pedal-shaped inferior end. We identified several types of cell clusters as candidates for the ultimobranchial body, but morphologically most of them were, to various degrees, likely to correspond to the blind end of the lower pouch when cut tangentially. Because of the topographical relation to the common carotid artery, a cyst-like structure with a cell cluster seemed to be the most likely candidate of the ultimobranchial body (a common anlage of the thymus and parathyroid). However, we were not able to deny a possibility that a certain plane cutting the pouch end incidentally provided such a cyst-like structure in sections. At any stage, the ultimobranchial body might not appear as a definite structure that is discriminated from others with routine staining. A concept of the ultimobranchial body might be biased by comparative anatomy that shows the ultimobranchial gland in adult birds and reptiles.

  1. CRNL library serials list

    International Nuclear Information System (INIS)

    Alburger, T.P.

    1982-04-01

    A list of 1900 serial publications (periodicals, society transactions and proceedings, annuals and directories, indexes, newspapers, etc.) is presented with volumes and years held by the Main Library. This library is the largest in AECL as well as one of the largest scientific and technical libraries in North America, and functions as a Canadian resource for nuclear information. A main alphabetical list is followed by broad subject field lists representing research interests, and lists of abstract and index serials, general bibliographic serials, conference indexes, press releases, English translations, and original language journals

  2. SU-E-J-263: Repeatability of SUV and Texture Parameters in Serial PET Studies

    Energy Technology Data Exchange (ETDEWEB)

    Schwartz, J; Humm, J; Nehmeh, S; Schoder, H [Memorial Sloan-Kettering Cancer Center, New York, NY (United States)

    2015-06-15

    Purpose: Standardized uptake values (SUV) are standard quantitative PET measures of FDG tumor uptake used,and are used as a tool to monitor response to therapy. Textural analysis is emerging as a new tool for assessing intratumoral heterogeneity which may allow better tissue characterization and improved prediction of response and survival rate.Understanding what variations may be expected in these parameters is key in order to make decisions based on how the change throughout the course of treatment. The aim of this study was to assess repeatability in SUV measures and texture parameters,and establish criteria that differentiate changes associated with treatment rather than statistical variability. Methods: Eighty patients,167 random lesions total,were scanned in a GE Discovery STE PET/CT Scanner. One field-of-view was chosen centered on the largest lesion observed in a clinical whole-body FDG PET.Immediately following,a gated 9 min scan was acquired in list mode,without changing the patient’s position between any scans. Data was replayed into 3 time bins,3 min each,in order to insure equivalent noise characteristics in each replicate.Data was reconstructed into 128×128×47 square matrices.One VOI was drawn over each lesion for each patient and used to segment all 3 replicates. The mean.max and peak SUV were calculated for each VOI and replicate. First-order textural features were also calculated (skewness and kurtosis). Repeatability was calculated as the average standard deviation over the mean for the 3 repeated measurements for each lesion. Results: The average percent error in the SUV max,peak and mean were 3.4%(0– 12.9%),1.9% (0–7.5%),2.8% (0–12.2%),respectively.For skewness and kurtosis they were 10.9% and 17.8%. Conclusion: We have shown that there is a large variation in %error in SUV measures across patients. SUVpeak is the least variable and kurtosis and skewness parameters are less reliable thatn SUVs.Higher order textures are be.

  3. SU-E-J-263: Repeatability of SUV and Texture Parameters in Serial PET Studies

    International Nuclear Information System (INIS)

    Schwartz, J; Humm, J; Nehmeh, S; Schoder, H

    2015-01-01

    Purpose: Standardized uptake values (SUV) are standard quantitative PET measures of FDG tumor uptake used,and are used as a tool to monitor response to therapy. Textural analysis is emerging as a new tool for assessing intratumoral heterogeneity which may allow better tissue characterization and improved prediction of response and survival rate.Understanding what variations may be expected in these parameters is key in order to make decisions based on how the change throughout the course of treatment. The aim of this study was to assess repeatability in SUV measures and texture parameters,and establish criteria that differentiate changes associated with treatment rather than statistical variability. Methods: Eighty patients,167 random lesions total,were scanned in a GE Discovery STE PET/CT Scanner. One field-of-view was chosen centered on the largest lesion observed in a clinical whole-body FDG PET.Immediately following,a gated 9 min scan was acquired in list mode,without changing the patient’s position between any scans. Data was replayed into 3 time bins,3 min each,in order to insure equivalent noise characteristics in each replicate.Data was reconstructed into 128×128×47 square matrices.One VOI was drawn over each lesion for each patient and used to segment all 3 replicates. The mean.max and peak SUV were calculated for each VOI and replicate. First-order textural features were also calculated (skewness and kurtosis). Repeatability was calculated as the average standard deviation over the mean for the 3 repeated measurements for each lesion. Results: The average percent error in the SUV max,peak and mean were 3.4%(0– 12.9%),1.9% (0–7.5%),2.8% (0–12.2%),respectively.For skewness and kurtosis they were 10.9% and 17.8%. Conclusion: We have shown that there is a large variation in %error in SUV measures across patients. SUVpeak is the least variable and kurtosis and skewness parameters are less reliable thatn SUVs.Higher order textures are be

  4. Macular hole formation, progression, and surgical repair: case series of serial optical coherence tomography and time lapse morphing video study

    Science.gov (United States)

    2010-01-01

    Background To use a new medium to dynamically visualize serial optical coherence tomography (OCT) scans in order to illustrate and elucidate the pathogenesis of idiopathic macular hole formation, progression, and surgical closure. Case Presentations Two patients at the onset of symptoms with early stage macular holes and one patient following repair were followed with serial OCTs. Images centered at the fovea and at the same orientation were digitally exported and morphed into an Audiovisual Interleaving (avi) movie format. Morphing videos from serial OCTs allowed the OCTs to be viewed dynamically. The videos supported anterior-posterior vitreofoveal traction as the initial event in macular hole formation. Progression of the macular hole occurred with increased cystic thickening of the fovea without evidence of further vitreofoveal traction. During cyst formation, the macular hole enlarged as the edges of the hole became elevated from the retinal pigment epithelium (RPE) with an increase in subretinal fluid. Surgical repair of a macular hole revealed initial closure of the macular hole with subsequent reabsorption of the sub-retinal fluid and restoration of the foveal contour. Conclusions Morphing videos from serial OCTs are a useful tool and helped illustrate and support anterior-posterior vitreofoveal traction with subsequent retinal hydration as the pathogenesis of idiopathic macular holes. PMID:20849638

  5. Playing at Serial Acquisitions

    NARCIS (Netherlands)

    J.T.J. Smit (Han); T. Moraitis (Thras)

    2010-01-01

    textabstractBehavioral biases can result in suboptimal acquisition decisions-with the potential for errors exacerbated in consolidating industries, where consolidators design serial acquisition strategies and fight escalating takeover battles for platform companies that may determine their future

  6. Classifying serial killers.

    Science.gov (United States)

    Promish, D I; Lester, D

    1999-11-08

    We attempted to match the appearance and demeanor of 27 serial killers to the postmortem 'signatures' found on their victims' bodies. Our results suggest that a link may exist between postmortem signatures and two complementary appearance-demeanor types.

  7. Role of Serial Polio Seroprevalence Studies in Guiding Implementation of the Polio Eradication Initiative in Kano, Nigeria: 2011-2014.

    Science.gov (United States)

    Craig, Kehinde TemilolaOluwa; Verma, Harish; Iliyasu, Zubairu; Mkanda, Pascal; Touray, Kebba; Johnson, Ticha; Walla, Abdullahi; Banda, Richard; Tegegne, Sisay G; Yehualashet, Yared G; Abba, Bashir; Ahmad-Shehu, Amina; Takane, Marina; Sutter, Roland W; Nsubuga, Peter; Muhammad, Ado J G; Vaz, Rui G

    2016-05-01

    Nigeria was one of 3 polio-endemic countries before it was de-listed in September 2015 by the World Health Organization, following interruption of transmission of the poliovirus. During 2011-2014, Nigeria conducted serial polio seroprevalence surveys (SPS) in Kano Metropolitan Area, comprising 8 local government areas (LGAs) in Kano that is considered very high risk (VHR) for polio, to monitor performance of the polio eradication program and guide the program in the adoption of innovative strategies. Study subjects who resided in any of the 8 local government areas of Kano Metropolitan Area and satisfied age criteria were recruited from patients at Murtala Mohammed Specialist Hospital (Kano) for 3 seroprevalence surveys. The same methods were used to conduct each survey. The 2011 study showed seroprevalence values of 81%, 75%, and 73% for poliovirus types 1, 2, and 3, respectively, among infants aged 6-9 months age. Among children aged 36-47 months, seroprevalence values were greater (91%, 87%, and 85% for poliovirus types 1, 2, and 3, respectively).In 2013, the results showed that the seroprevalence was unexpectedly low among infants aged 6-9 months, remained high among children aged 36-47 months, and increased minimally among children aged 5-9 years and those aged 10-14 years. The baseline seroprevalence among infants aged 6-9 months in 2014 was better than that in 2013. The results from the polio seroprevalence surveys conducted in Kano Metropolitan Area in 2011, 2013, and 2014 served to assess the trends in immunity and program performance, as well as to guide the program, leading to various interventions being implemented with good effect, as evidenced by the reduction of poliovirus circulation in Kano. © 2016 World Health Organization; licensee Oxford Journals.

  8. A Study on the Nuclear Technology Policy

    International Nuclear Information System (INIS)

    Lim, C. Y.; Lee, K. S.; Jeong, I.; Lee, J. H.

    2009-04-01

    The objective of the study was to make policy-proposes for enhancing the effectiveness and efficiency of national nuclear technology development programs. To do this, recent changes of international nuclear energy policy and trends of nuclear technology R and D was surveyed and analyzed. In the viewpoint of analysis of the changes in the global policy surrounding nuclear technology development and development of national nuclear R and D strategy, this study (1) analyzed the trends of nuclear technology policies and (2) discussed the mid and long term strategy of nuclear energy R and D. To put it in more detail, each subject was further explored as follows; (1) analyzed the trends of nuclear technology policies - Trend and prospects of the international and domestic nuclear policies - Investigation of development of small and medium sized policies - International collaboration for advanced nuclear technologies (2) discussed the mid and long term strategy of nuclear energy R and D - The long term development plan for future nuclear energy system - The facilitation of technology commercialization

  9. Reframing Serial Murder Within Empirical Research.

    Science.gov (United States)

    Gurian, Elizabeth A

    2017-04-01

    Empirical research on serial murder is limited due to the lack of consensus on a definition, the continued use of primarily descriptive statistics, and linkage to popular culture depictions. These limitations also inhibit our understanding of these offenders and affect credibility in the field of research. Therefore, this comprehensive overview of a sample of 508 cases (738 total offenders, including partnered groups of two or more offenders) provides analyses of solo male, solo female, and partnered serial killers to elucidate statistical differences and similarities in offending and adjudication patterns among the three groups. This analysis of serial homicide offenders not only supports previous research on offending patterns present in the serial homicide literature but also reveals that empirically based analyses can enhance our understanding beyond traditional case studies and descriptive statistics. Further research based on these empirical analyses can aid in the development of more accurate classifications and definitions of serial murderers.

  10. Serial Changes in Sexual Function Following Holmium Laser Enucleation of the Prostate: A Short-term Follow-up Study.

    Science.gov (United States)

    Jeong, Min Su; Ha, Seung Beom; Lee, Chang Ju; Cho, Min Chul; Kim, Soo Woong; Paick, Jae-Seung

    2012-02-01

    To evaluate the serial changes in sexual function in the short-term period after holmium laser enucleation of the prostate (HoLEP) for benign prostatic hyperplasia (BPH) and to investigate whether a change in each domain of the International Index of Erectile Function (IIEF) is associated with improvement of micturition. Thirty-eight potent men who underwent HoLEP and in whom complete 12-month follow-up data on the IIEF were available were included in this retrospective study. All patients underwent a baseline evaluation for BPH. The surgical outcome was evaluated at 1, 3, 6, and 12 months postoperatively by use of the International Prostate Symptom Score, IIEF, and uroflowmetry. The mean age and body mass index of the patients was 64.5±6.2 years and 24.2±2.6 kg/m(2), respectively. Mean total prostate volume and transitional zone volume were 48.8±18.8 ml and 24.2±16.1 ml, respectively. Most IIEF domain scores showed a slight decrease at 1, 3, and 6 months after surgery but recovered to the baseline or showed a marginal but nonsignificant increase at 12 months postoperatively compared with baseline. Orgasmic function and the overall sexual satisfaction domain score remained slightly reduced up to 12 months postoperatively. There was no significant correlation between improvement of micturition and change in sexual function throughout the follow-up period after surgery. Although HoLEP achieves significant improvements in micturition, overall sexual function decreases slightly in the early postoperative period, but recovers to the baseline at 12 months postoperatively. Our data suggest that changes in sexual function after HoLEP are not associated with improvement of micturition.

  11. Median Sacral Artery, Sympathetic Nerves, and the Coccygeal Body: A Study Using Serial Sections of Human Embryos and Fetuses.

    Science.gov (United States)

    Jin, Zhe Wu; Cho, Kwang Ho; Jang, Hyung Suk; Murakami, Gen; Rodríguez-Vázquez, Jose Francisco

    2016-07-01

    To examine how the median sacral artery (MSA) is involved with the coccygeal body or glomus coccygeum, we studied serial frontal or sagittal sections of 14 embryos (approximately 5-6 weeks of gestation) and 12 fetuses (10-18 weeks). At five weeks, the caudal end of the dorsal aorta (i.e., MSA) accompanied putative sympathetic ganglion cells in front of the upper coccygeal and lower sacral vertebrae. At six weeks, a candidate for the initial coccygeal body was identified as a longitudinal arterial plexus involving nerve fibers and sympathetic ganglion cells between arteries. At 10-18 weeks, the MSA exhibited a highly tortuous course at the lower sacral and coccygeal levels, and was attached to and surrounded by veins, nerve fibers, and sympathetic ganglion cells near and between the bilateral origins of the levator ani muscle. Immunohistochemistry demonstrated expression of tyrosine hydroxylase and chromogranin A in the nerves. However, throughout the stages examined, we found no evidence suggestive of an arteriovenous anastomosis, such as well-developed smooth muscle. An acute anterior flexure of the vertebrae at the lower sacrum, as well as regression of the secondary neural tube, seemed to induce arterial plexus formation from an initial straight MSA. Nerves and ganglion cells were likely to be secondarily involved with the plexus because of the close topographical relationship. However, these nerves might play a major role in the extreme change into adult morphology. An arteriovenous anastomosis along the MSA might be an overinterpretation, at least in the prenatal human. Anat Rec, 299:819-827, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  12. Magnetic resonance imaging of skeletal muscle in patients with Duchenne muscular dystrophy; Serial axial and sagittal section studies

    Energy Technology Data Exchange (ETDEWEB)

    Nagao, Hideo (Ehime Univ., Matsuyama (Japan). Faculty of Education); Morimoto, Takehiko; Sano, Nozomi; Takahashi, Mitsugi; Nagai, Hironao; Tawa, Ritsuko; Yoshimatsu, Makoto; Woo Young-Jong; Matsuda, Hiroshi

    1991-01-01

    Magnetic resonance imaging of skeletal muscles in thirteen patients with Duchenne muscular dystrophy was performed to estimate pathological changes. Serial axial and sagittal sections of the right lower extremity were recorded. In the early stage, the T{sub 1} values of gastrocnemius and soleus muscles were slightly lower than the control values, and in the late stage, the values were much lower in all muscles examined. In sagittal sections, the gastrocnemius muscle in the early stage showed a high density area at the distal region adjacent to soleus muscle, and the soleus muscle showed a high density area adjacent to the gestrocnemius muscle. In serial axial sections, high density areas of the anterior and posterior tibialis muscles appeared first at their proximal and peripheral regions. It was concluded that the sequence of appearance of pathological changes was different not only among individual muscles but also among various regions of each muscle; the high density changes appeared first at myotendon junctions. (author).

  13. The Windows serial port programming handbook

    CERN Document Server

    Bai, Ying

    2004-01-01

    The fundamentals of serial port communications. Serial port programming in ANSI C and Assembly languages for MS-DOS. Serial ports interface developed in VC++ 6.0. Serial port programming in Visual Basic. Serial port programming in LabVIEW. Serial port programming in MATLAB. Serial port programming in Smalltalk. Serial port programming in Java.

  14. Globalization and Public Policy Analysis: A Case Study of Foreign Policy of ASEAN Member States

    OpenAIRE

    Nattapol Pourprasert

    2016-01-01

    This study has an objective to analyze foreign policy of member states in globalization current, aiming to answer that the foreign policy of member states have been changed or remained the same and there are any factors affecting changing of foreign policy of the member states. From the study results, it is found that the foreign policy of Thailand is a friendly foreign policy with all states. The policy of Indonesia is more opened because of a change in leader, allowing ...

  15. Semi-automatic analysis of standard uptake values in serial PET/CT studies in patients with lung cancer and lymphoma

    Directory of Open Access Journals (Sweden)

    Ly John

    2012-04-01

    Full Text Available Abstract Background Changes in maximum standardised uptake values (SUVmax between serial PET/CT studies are used to determine disease progression or regression in oncologic patients. To measure these changes manually can be time consuming in a clinical routine. A semi-automatic method for calculation of SUVmax in serial PET/CT studies was developed and compared to a conventional manual method. The semi-automatic method first aligns the serial PET/CT studies based on the CT images. Thereafter, the reader selects an abnormal lesion in one of the PET studies. After this manual step, the program automatically detects the corresponding lesion in the other PET study, segments the two lesions and calculates the SUVmax in both studies as well as the difference between the SUVmax values. The results of the semi-automatic analysis were compared to that of a manual SUVmax analysis using a Philips PET/CT workstation. Three readers did the SUVmax readings in both methods. Sixteen patients with lung cancer or lymphoma who had undergone two PET/CT studies were included. There were a total of 26 lesions. Results Linear regression analysis of changes in SUVmax show that intercepts and slopes are close to the line of identity for all readers (reader 1: intercept = 1.02, R2 = 0.96; reader 2: intercept = 0.97, R2 = 0.98; reader 3: intercept = 0.99, R2 = 0.98. Manual and semi-automatic method agreed in all cases whether SUVmax had increased or decreased between the serial studies. The average time to measure SUVmax changes in two serial PET/CT examinations was four to five times longer for the manual method compared to the semi-automatic method for all readers (reader 1: 53.7 vs. 10.5 s; reader 2: 27.3 vs. 6.9 s; reader 3: 47.5 vs. 9.5 s; p Conclusions Good agreement was shown in assessment of SUVmax changes between manual and semi-automatic method. The semi-automatic analysis was four to five times faster to perform than the manual analysis. These findings show the

  16. Serial Network Flow Monitor

    Science.gov (United States)

    Robinson, Julie A.; Tate-Brown, Judy M.

    2009-01-01

    Using a commercial software CD and minimal up-mass, SNFM monitors the Payload local area network (LAN) to analyze and troubleshoot LAN data traffic. Validating LAN traffic models may allow for faster and more reliable computer networks to sustain systems and science on future space missions. Research Summary: This experiment studies the function of the computer network onboard the ISS. On-orbit packet statistics are captured and used to validate ground based medium rate data link models and enhance the way that the local area network (LAN) is monitored. This information will allow monitoring and improvement in the data transfer capabilities of on-orbit computer networks. The Serial Network Flow Monitor (SNFM) experiment attempts to characterize the network equivalent of traffic jams on board ISS. The SNFM team is able to specifically target historical problem areas including the SAMS (Space Acceleration Measurement System) communication issues, data transmissions from the ISS to the ground teams, and multiple users on the network at the same time. By looking at how various users interact with each other on the network, conflicts can be identified and work can begin on solutions. SNFM is comprised of a commercial off the shelf software package that monitors packet traffic through the payload Ethernet LANs (local area networks) on board ISS.

  17. Reliability of mechanical and phased-array designs for serial intravascular ultrasound examinations--animal and clinical studies in stented and non-stented coronary arteries.

    Science.gov (United States)

    Tardif, J C; Bertrand, O F; Mongrain, R; Lespérance, J; Grégoire, J; Paiement, P; Bonan, R

    2000-10-01

    Both mechanical and multi-element intravascular ultrasound designs have potential advantages and limitations that may impact on their value for clinical and research purposes. Determination of the reproducibility of measurements is critical before a given system can be used in studies such as regression of atherosclerosis trials. We performed serial intravascular ultrasound imaging with catheters using mechanical and phased-array designs in stented and non-stented coronary arteries in dogs and in patients. Both systems correlated well for areas (r > or = 0.90, p or = 0.84. p mechanical designs for measurements of area (mean difference in dogs and in patients: -0.24 and 0.96 mm2, p mechanical system (r > or = 0.96 for all measurements). The differences in absolute and relative variability between the mechanical and phased-array designs, both for reanalysis of same frames and serial pullbacks, were very small. Although multi-element and mechanical intravascular ultrasound designs are not strictly interchangeable, their similar reproducibility and the small differences in measurements demonstrate that both designs are acceptable alternatives for trials of regression of atherosclerosis. Determination of the variability for serial pullbacks of both designs was also important to assess the statistical power of such trials.

  18. Serial interprocessor communications system

    International Nuclear Information System (INIS)

    Labiak, W.; Siemens, P.; Bailey, C.

    1980-01-01

    A serial communications system based on the EIA RS232-C standard with modem control lines has been developed. The DLV11-E interface is used for this purpose. All handshaking is done with the modem control lines. This allows totally independent full duplex communication. The message format consists of eight bit data with odd parity and a sixteen bit checksum on the whole message. All communications are fully interrupt driven. A program was written to load a program into a remote LSI-11 using the serial line without bootstrap ROM

  19. A Study on the Nuclear Technology Policy

    Energy Technology Data Exchange (ETDEWEB)

    Kim, H. J.; Lim, C. Y.; Yang, M. H. (and others)

    2008-03-15

    The objective of the study was to make policy-proposes for enhancing the effectiveness and efficiency of national nuclear technology development programs. To do this, changes of international nuclear energy policy environment and trends of nuclear technology development was surveyed and analyzed. In the viewpoint of analysis of the changes in the global policy environment surrounding nuclear technology development and development of national nuclear R and D strategy, this study (1) analyzed trends of nuclear technology policies and (2) developed the nuclear energy R and D innovation strategies. To put it in more detail, each subject was further explored as follows; (1) themes to analyze trends of nuclear policies: nuclear Renaissance and forecast for nuclear power plant, International collaboration for advanced nuclear technologies in GIF, INPRO and I-NERI, The present situation and outlook for world uranium market (2) themes to develop of nuclear energy R and D innovation strategies: The mid-term strategy plan of the KAERI, The technological innovation case of the KAERI.

  20. A Study on the Nuclear Technology Policy

    International Nuclear Information System (INIS)

    Kim, H. J.; Lim, C. Y.; Yang, M. H.

    2008-03-01

    The objective of the study was to make policy-proposes for enhancing the effectiveness and efficiency of national nuclear technology development programs. To do this, changes of international nuclear energy policy environment and trends of nuclear technology development was surveyed and analyzed. In the viewpoint of analysis of the changes in the global policy environment surrounding nuclear technology development and development of national nuclear R and D strategy, this study (1) analyzed trends of nuclear technology policies and (2) developed the nuclear energy R and D innovation strategies. To put it in more detail, each subject was further explored as follows; (1) themes to analyze trends of nuclear policies: nuclear Renaissance and forecast for nuclear power plant, International collaboration for advanced nuclear technologies in GIF, INPRO and I-NERI, The present situation and outlook for world uranium market (2) themes to develop of nuclear energy R and D innovation strategies: The mid-term strategy plan of the KAERI, The technological innovation case of the KAERI

  1. Nanoflow electrospinning serial femtosecond crystallography

    Energy Technology Data Exchange (ETDEWEB)

    Sierra, Raymond G.; Laksmono, Hartawan [SLAC National Accelerator Laboratory, Menlo Park, CA 94025 (United States); Kern, Jan [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States); SLAC National Accelerator Laboratory, Menlo Park, CA 94025 (United States); Tran, Rosalie; Hattne, Johan [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States); Alonso-Mori, Roberto [SLAC National Accelerator Laboratory, Menlo Park, CA 94025 (United States); Lassalle-Kaiser, Benedikt [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States); Glöckner, Carina; Hellmich, Julia [Technische Universität Berlin, Strasse des 17 Juni 135, 10623 Berlin (Germany); Schafer, Donald W. [SLAC National Accelerator Laboratory, Menlo Park, CA 94025 (United States); Echols, Nathaniel; Gildea, Richard J.; Grosse-Kunstleve, Ralf W. [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States); Sellberg, Jonas [SLAC National Accelerator Laboratory, Menlo Park, CA 94025 (United States); Stockholm University, S-106 91 Stockholm (Sweden); McQueen, Trevor A. [Stanford University, Stanford, CA 94025 (United States); Fry, Alan R.; Messerschmidt, Marc M.; Miahnahri, Alan; Seibert, M. Marvin; Hampton, Christina Y.; Starodub, Dmitri; Loh, N. Duane; Sokaras, Dimosthenis; Weng, Tsu-Chien [SLAC National Accelerator Laboratory, Menlo Park, CA 94025 (United States); Zwart, Petrus H. [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States); Glatzel, Pieter [European Synchrotron Radiation Facility, Grenoble (France); Milathianaki, Despina; White, William E. [SLAC National Accelerator Laboratory, Menlo Park, CA 94025 (United States); Adams, Paul D. [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States); Williams, Garth J.; Boutet, Sébastien [SLAC National Accelerator Laboratory, Menlo Park, CA 94025 (United States); Zouni, Athina [Technische Universität Berlin, Strasse des 17 Juni 135, 10623 Berlin (Germany); Messinger, Johannes [Umeå Universitet, Umeå (Sweden); Sauter, Nicholas K. [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States); Bergmann, Uwe [SLAC National Accelerator Laboratory, Menlo Park, CA 94025 (United States); Yano, Junko; Yachandra, Vittal K. [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States); Bogan, Michael J., E-mail: mbogan@slac.stanford.edu [SLAC National Accelerator Laboratory, Menlo Park, CA 94025 (United States); SLAC National Accelerator Laboratory, Menlo Park, CA 94025 (United States)

    2012-11-01

    A low flow rate liquid microjet method for delivery of hydrated protein crystals to X-ray lasers is presented. Linac Coherent Light Source data demonstrates serial femtosecond protein crystallography with micrograms, a reduction of sample consumption by orders of magnitude. An electrospun liquid microjet has been developed that delivers protein microcrystal suspensions at flow rates of 0.14–3.1 µl min{sup −1} to perform serial femtosecond crystallography (SFX) studies with X-ray lasers. Thermolysin microcrystals flowed at 0.17 µl min{sup −1} and diffracted to beyond 4 Å resolution, producing 14 000 indexable diffraction patterns, or four per second, from 140 µg of protein. Nanoflow electrospinning extends SFX to biological samples that necessitate minimal sample consumption.

  2. Nanoflow electrospinning serial femtosecond crystallography

    International Nuclear Information System (INIS)

    Sierra, Raymond G.; Laksmono, Hartawan; Kern, Jan; Tran, Rosalie; Hattne, Johan; Alonso-Mori, Roberto; Lassalle-Kaiser, Benedikt; Glöckner, Carina; Hellmich, Julia; Schafer, Donald W.; Echols, Nathaniel; Gildea, Richard J.; Grosse-Kunstleve, Ralf W.; Sellberg, Jonas; McQueen, Trevor A.; Fry, Alan R.; Messerschmidt, Marc M.; Miahnahri, Alan; Seibert, M. Marvin; Hampton, Christina Y.; Starodub, Dmitri; Loh, N. Duane; Sokaras, Dimosthenis; Weng, Tsu-Chien; Zwart, Petrus H.; Glatzel, Pieter; Milathianaki, Despina; White, William E.; Adams, Paul D.; Williams, Garth J.; Boutet, Sébastien; Zouni, Athina; Messinger, Johannes; Sauter, Nicholas K.; Bergmann, Uwe; Yano, Junko; Yachandra, Vittal K.; Bogan, Michael J.

    2012-01-01

    A low flow rate liquid microjet method for delivery of hydrated protein crystals to X-ray lasers is presented. Linac Coherent Light Source data demonstrates serial femtosecond protein crystallography with micrograms, a reduction of sample consumption by orders of magnitude. An electrospun liquid microjet has been developed that delivers protein microcrystal suspensions at flow rates of 0.14–3.1 µl min −1 to perform serial femtosecond crystallography (SFX) studies with X-ray lasers. Thermolysin microcrystals flowed at 0.17 µl min −1 and diffracted to beyond 4 Å resolution, producing 14 000 indexable diffraction patterns, or four per second, from 140 µg of protein. Nanoflow electrospinning extends SFX to biological samples that necessitate minimal sample consumption

  3. Serial killer: il database mondiale

    Directory of Open Access Journals (Sweden)

    Gaetano parente

    2016-07-01

    Full Text Available The complex and multisided study of serial killers is partly made difficult by the current level of progress that has led these deviant people to evolve in relation to the aspects of shrewdness (concerning the staging and mobility. Despite the important work of some scholars who proposed important theories, all this shows that, concerning serial murders, it is still particularly frequent not to pay attention to links among homicides committed by the same person but in different parts of the world. It is therefore crucial to develop a worldwide database that allows all police forces to access information collected on crime scenes of murders which are particularly absurd and committed without any apparent reason. It will then be up to the profiler, through ad hoc and technologically advanced tools, to collect this information on the crime scene that would be made available to all police forces thanks to the worldwide database.

  4. Serial forced displacement in American cities, 1916-2010.

    Science.gov (United States)

    Fullilove, Mindy Thompson; Wallace, Rodrick

    2011-06-01

    Serial forced displacement has been defined as the repetitive, coercive upheaval of groups. In this essay, we examine the history of serial forced displacement in American cities due to federal, state, and local government policies. We propose that serial forced displacement sets up a dynamic process that includes an increase in interpersonal and structural violence, an inability to react in a timely fashion to patterns of threat or opportunity, and a cycle of fragmentation as a result of the first two. We present the history of the policies as they affected one urban neighborhood, Pittsburgh's Hill District. We conclude by examining ways in which this problematic process might be addressed.

  5. From animal cruelty to serial murder: applying the graduation hypothesis.

    Science.gov (United States)

    Wright, Jeremy; Hensley, Christopher

    2003-02-01

    Although serial murder has been recorded for centuries, limited academic attention has been given to this important topic. Scholars have attempted to examine the causality and motivations behind the rare phenomenon of serial murder. However, scant research exists which delves into the childhood characteristics of serial murderers. Using social learning theory, some of these studies present supporting evidence for a link between childhood animal cruelty and adult aggression toward humans. Based on five case studies of serial murderers, we contribute to the existing literature by exploring the possible link between childhood cruelty toward animals and serial murder with the application of the graduation hypothesis.

  6. Selection and Serial Entrepreneurs

    DEFF Research Database (Denmark)

    Chen, Jing

    2013-01-01

    There is substantial evidence that serial entrepreneurs outperform de novo entrepreneurs. But is this positive association between prior experience and performance the result of learning by doing or of selection on ability? This paper proposes a strategy that combines the fixed-effects model and IV...... when the analysis focuses on founding new startups in sectors closely related to entrepreneurs' previous ventures....

  7. Selection and Serial Entrepreneurs

    DEFF Research Database (Denmark)

    Chen, Jing

    2011-01-01

    Although it has been broadly evidenced that entrepreneurial experience plays a substantial role in the emergence of serial entrepreneurship, the debate is still going on about whether this relationship should be attributed to learning by doing or instead be explained by selection on ability. This...

  8. Serial private infrastructures

    NARCIS (Netherlands)

    van den Berg, V.A.C.

    2013-01-01

    This paper investigates private supply of two congestible infrastructures that are serial, where the consumer has to use both in order to consume. Four market structures are analysed: a monopoly and 3 duopolies that differ in how firms interact. It is well known that private supply leads too high

  9. Stress in Harmonic Serialism

    Science.gov (United States)

    Pruitt, Kathryn Ringler

    2012-01-01

    This dissertation proposes a model of word stress in a derivational version of Optimality Theory (OT) called Harmonic Serialism (HS; Prince and Smolensky 1993/2004, McCarthy 2000, 2006, 2010a). In this model, the metrical structure of a word is derived through a series of optimizations in which the "best" metrical foot is chosen…

  10. Suicide in serial killers.

    Science.gov (United States)

    Lester, David; White, John

    2010-02-01

    In a sample of 248 killers of two victims in America from 1900 to 2005, obtained from an encyclopedia of serial killers by Newton (2006), those completing suicide did not differ in sex, race, or the motive for the killing from those who were arrested.

  11. Soutien institutionnel à African Technology Policy Studies ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Au départ la division tanzanienne du Réseau d'études sur la politique technologique en Afrique (African Technology Policy Studies Network), et ce, depuis 1984, ATPS-Tanzania est devenu autonome à titre d'organisation non gouvernementale en 2001. Lorsque ATPS-Tanzania recevait un financement stable du siège de ...

  12. Institutional Support : African Technology Policy Studies - Tanzania ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    African Technology Policy Studies - Tanzania (ATPS-Tanzania) was registered as a national nongovernmental organization in 2001. ... While resource flows to ATPS-Tanzania from ATPS headquarters in Nairobi were reliable, the organization produced a larger volume of research outputs than most other ATPS national ...

  13. Serial murder by healthcare professionals.

    Science.gov (United States)

    Yorker, Beatrice Crofts; Kizer, Kenneth W; Lampe, Paula; Forrest, A R W; Lannan, Jacquetta M; Russell, Donna A

    2008-01-01

    The prosecution of Charles Cullen, a nurse who killed at least 40 patients over a 16-year period, highlights the need to better understand the phenomenon of serial murder by healthcare professionals. The authors conducted a LexisNexis search which yielded 90 criminal prosecutions of healthcare providers that met inclusion criteria for serial murder of patients. In addition we reviewed epidemiologic studies, toxicology evidence, and court transcripts, to provide data on healthcare professionals who have been prosecuted between 1970 and 2006. Fifty-four of the 90 have been convicted; 45 for serial murder, four for attempted murder, and five pled guilty to lesser charges. Twenty-four more have been indicted and are either awaiting trial or the outcome has not been published. The other 12 prosecutions had a variety of legal outcomes. Injection was the main method used by healthcare killers followed by suffocation, poisoning, and tampering with equipment. Prosecutions were reported from 20 countries with 40% taking place in the United States. Nursing personnel comprised 86% of the healthcare providers prosecuted; physicians 12%, and 2% were allied health professionals. The number of patient deaths that resulted in a murder conviction is 317 and the number of suspicious patient deaths attributed to the 54 convicted caregivers is 2113. These numbers are disturbing and demand that systemic changes in tracking adverse patient incidents associated with presence of a specific healthcare provider be implemented. Hiring practices must shift away from preventing wrongful discharge or denial of employment lawsuits to protecting patients from employees who kill.

  14. A Survey of Electronic Serials Managers Reveals Diversity in Practice

    Directory of Open Access Journals (Sweden)

    Laura Costello

    2014-09-01

    In surveying academic librarians engaged in serials management, the author sought to identify trends and standards in the field, but instead found significant variation in serials budgets and processes amongst the responding libraries. While it is clear that electronic subscriptions are a significant development and now a permanent feature of serials management, decisions to move from print to digital are complex and definitive conclusions about best practices for serials transitions could not be drawn from this study. The survey revealed that institutions have invested in staff and tools for the management of electronic serials, but staffing configurations and tool combinations are also extremely diverse. The author concluded that the lack of standardization in these areas and the disconnect between institution and serials budget size indicated a serials landscape that was highly individualized and customized to each institution’s unique needs.

  15. A study on the nuclear foreign policy

    International Nuclear Information System (INIS)

    Lee, Byungwook; Lee, H. M.; Ko, H. S.; Ryu, J. S.; Noh, B. C.

    2008-12-01

    This study addresses four arenas to effectively assist national nuclear foreign policies under international nuclear nonproliferation regimes and organizations. Firstly, this study analyzes the trends of the international nuclear non-proliferation regime, which includes the Treaty on the Non-proliferation of Nuclear Weapons (NPT), the international nuclear export control regime, and proposals for assurance of nuclear fuel supply. Secondly, this study analyzes the trends of international nuclear organizations, which include the IAEA as a central body of international nuclear diplomacy and technical cooperation and the OECD/NEA as a intergovernmental organization to consist of nuclear advanced countries. Thirdly, this study predicts the nuclear foreign policy of Obama Administration and reviews U. S.-India nuclear cooperation. Lastly, this study analyzes the nuclear issues of North Korea and current issues for regulation of nuclear materials.

  16. Serial Expression Analysis: a web tool for the analysis of serial gene expression data

    Science.gov (United States)

    Nueda, Maria José; Carbonell, José; Medina, Ignacio; Dopazo, Joaquín; Conesa, Ana

    2010-01-01

    Serial transcriptomics experiments investigate the dynamics of gene expression changes associated with a quantitative variable such as time or dosage. The statistical analysis of these data implies the study of global and gene-specific expression trends, the identification of significant serial changes, the comparison of expression profiles and the assessment of transcriptional changes in terms of cellular processes. We have created the SEA (Serial Expression Analysis) suite to provide a complete web-based resource for the analysis of serial transcriptomics data. SEA offers five different algorithms based on univariate, multivariate and functional profiling strategies framed within a user-friendly interface and a project-oriented architecture to facilitate the analysis of serial gene expression data sets from different perspectives. SEA is available at sea.bioinfo.cipf.es. PMID:20525784

  17. A study on the nuclear technology policy

    International Nuclear Information System (INIS)

    Yang, M. H.; Kim, H. J.; Chung, W. S.; Lee, T. J.; Yun, S. W.; Jeong, Ik

    2002-01-01

    This study was carried out as a part of institutional activities of KAERI. This study suggested the effective and systematic alternatives for the development of domestic industry through nuclear long-term R and D program while timely responding to the environmental change in local and global sense. First of all, this study investigated the current status and prospect of nuclear power supply, the global technological change of nuclear fuel cycle, the nuclear policy changes of major countries and the role of nuclear energy in East Asian countries. Second, some policy alternatives are suggested in association with the role of national R and D in enhancing industrial competitiveness, the effective management of nuclear long-term R and D program to facilitate technological innovation and the way to enlarge the utilization of nuclear R and D results and radiation technology

  18. Malaysian Serials: Issues and Problems.

    Science.gov (United States)

    Bahri, Che Norma

    This paper analyzes the issues and problems while looking at the trends and developments of serials publishing in Malaysia. The first section provides background; topics addressed include the country and people of Malaysia, the history of serials publishing in Malaysia, categories and formats of serials publishing, academic publications,…

  19. Delaware's first serial killer.

    Science.gov (United States)

    Inguito, G B; Sekula-Perlman, A; Lynch, M J; Callery, R T

    2000-11-01

    The violent murder of Shirley Ellis on November 29, 1987, marked the beginning of the strange and terrible tale of Steven Bryan Pennell's reign as the state of Delaware's first convicted serial killer. Three more bodies followed the first victim, and all had been brutally beaten and sadistically tortured. The body of a fifth woman has never been found. State and county police collaborated with the FBI to identify and hunt down their suspect, forming a task force of over 100 officers and spending about one million dollars. Through their knowledge and experience with other serial killers, the FBI was able to make an amazingly accurate psychological profile of Delaware's serial killer. After months of around-the-clock surveillance, Steven Pennell was arrested on November 29, 1988, one year to the day after the first victim was found. Pennell was found guilty in the deaths of the first two victims on November 29, 1989, and plead no contest to the murder of two others on October 30, 1991. Still maintaining his innocence, he asked for the death penalty so that he could spare his family further agony. Steven Pennell was executed by lethal injection on March 15, 1992.

  20. A serial ¹⁸FDG-PET study of a patient with SSPE who had good prognosis by combination therapy with interferon alpha and ribavirin.

    Science.gov (United States)

    Ohya, Takashi; Yamashita, Yushiro; Shibuya, Ikuhiko; Hara, Munetsugu; Nagamitsu, Shinichiro; Kaida, Hayato; Kurata, Seiji; Ishibashi, Masatoshi; Matsuishi, Toyojiro

    2014-07-01

    We describe a 15-year-old girl with subacute sclerosing panencephalitis (SSPE) in stage II who was treated with isoprinosine, intraventricular interferon alpha (IFN-α), and ribavirin for 3 years. She is alive at three years from onset and studies at school with the assistance of a special educational teacher. To assess residual brain function, serial (18)FDG-positron emission tomography (PET) was performed three times to measure cortical metabolism: at onset, a year later, and three years later. At onset, PET study revealed preserved glucose metabolism of the cerebral cortex. In serial PET study, glucose metabolism of the cerebral cortex was also preserved even after three years. Although SSPE is a progressive disease of the neuronal system, and typically leads to death in approximately 2-3 years, the neurological prognosis of our case was good. We consider that combination therapy in the very early stage without hypometabolism in the cerebral cortex may be effective for SSPE. Copyright © 2014 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

  1. A Study on Nuclear Technology Policy

    International Nuclear Information System (INIS)

    Oh, K. B.; Chung, W. S.; Lee, T. J.; Yun, S. W.; Jeong, Ik; Lee, J. H.

    2006-02-01

    This study was conducted as a part of institutional activities of KAERI, and the objective of the study is to survey and analyze the change of international environment in nuclear use and research and development environment, and to propose systematic alternatives on technology policy for efficiency and effectiveness of research and development through national R and D program while timely responding to the environmental change in local and global sense. In the investigation and analysis of international environmental and technological change 1. Viability of Nuclear Renaissance 2. Recent of Nuclear Technology Policy in Japan 3. Collaboration for Advanced Nuclear Technologies in GIF, INPRO and INERI 4. Nuclear Energy Utilization and Development in Europe. In the evaluation of nuclear technology and sustainable development from the point of views of environmental change 5. External Cost of Environmental Impact in Electric Power Sector 6. Nuclear Technology Development Direction Considering Changes of the Science and Technology Policy Environment 7. Nuclear Energy Development Strategy for a Sustainable National Energy Supply

  2. A Study on Nuclear Technology Policy

    Energy Technology Data Exchange (ETDEWEB)

    Oh, K B; Chung, W S; Lee, T J; Yun, S W; Jeong, Ik; Lee, J H

    2006-02-15

    This study was conducted as a part of institutional activities of KAERI, and the objective of the study is to survey and analyze the change of international environment in nuclear use and research and development environment, and to propose systematic alternatives on technology policy for efficiency and effectiveness of research and development through national R and D program while timely responding to the environmental change in local and global sense. In the investigation and analysis of international environmental and technological change 1. Viability of Nuclear Renaissance 2. Recent of Nuclear Technology Policy in Japan 3. Collaboration for Advanced Nuclear Technologies in GIF, INPRO and INERI 4. Nuclear Energy Utilization and Development in Europe. In the evaluation of nuclear technology and sustainable development from the point of views of environmental change 5. External Cost of Environmental Impact in Electric Power Sector 6. Nuclear Technology Development Direction Considering Changes of the Science and Technology Policy Environment 7. Nuclear Energy Development Strategy for a Sustainable National Energy Supply.

  3. The Processing of Somatosensory Information Shifts from an Early Parallel into a Serial Processing Mode: A Combined fMRI/MEG Study.

    Science.gov (United States)

    Klingner, Carsten M; Brodoehl, Stefan; Huonker, Ralph; Witte, Otto W

    2016-01-01

    The question regarding whether somatosensory inputs are processed in parallel or in series has not been clearly answered. Several studies that have applied dynamic causal modeling (DCM) to fMRI data have arrived at seemingly divergent conclusions. However, these divergent results could be explained by the hypothesis that the processing route of somatosensory information changes with time. Specifically, we suggest that somatosensory stimuli are processed in parallel only during the early stage, whereas the processing is later dominated by serial processing. This hypothesis was revisited in the present study based on fMRI analyses of tactile stimuli and the application of DCM to magnetoencephalographic (MEG) data collected during sustained (260 ms) tactile stimulation. Bayesian model comparisons were used to infer the processing stream. We demonstrated that the favored processing stream changes over time. We found that the neural activity elicited in the first 100 ms following somatosensory stimuli is best explained by models that support a parallel processing route, whereas a serial processing route is subsequently favored. These results suggest that the secondary somatosensory area (SII) receives information regarding a new stimulus in parallel with the primary somatosensory area (SI), whereas later processing in the SII is dominated by the preprocessed input from the SI.

  4. The Processing of Somatosensory Information shifts from an early parallel into a serial processing mode: a combined fMRI/MEG study.

    Directory of Open Access Journals (Sweden)

    Carsten Michael Klingner

    2016-12-01

    Full Text Available The question regarding whether somatosensory inputs are processed in parallel or in series has not been clearly answered. Several studies that have applied dynamic causal modeling (DCM to fMRI data have arrived at seemingly divergent conclusions. However, these divergent results could be explained by the hypothesis that the processing route of somatosensory information changes with time. Specifically, we suggest that somatosensory stimuli are processed in parallel only during the early stage, whereas the processing is later dominated by serial processing. This hypothesis was revisited in the present study based on fMRI analyses of tactile stimuli and the application of DCM to magnetoencephalographic (MEG data collected during sustained (260 ms tactile stimulation. Bayesian model comparisons were used to infer the processing stream. We demonstrated that the favored processing stream changes over time. We found that the neural activity elicited in the first 100 ms following somatosensory stimuli is best explained by models that support a parallel processing route, whereas a serial processing route is subsequently favored. These results suggest that the secondary somatosensory area (SII receives information regarding a new stimulus in parallel with the primary somatosensory area (SI, whereas later processing in the SII is dominated by the preprocessed input from the SI.

  5. Nanoflow electrospinning serial femtosecond crystallography

    Science.gov (United States)

    Sierra, Raymond G.; Laksmono, Hartawan; Kern, Jan; Tran, Rosalie; Hattne, Johan; Alonso-Mori, Roberto; Lassalle-Kaiser, Benedikt; Glöckner, Carina; Hellmich, Julia; Schafer, Donald W.; Echols, Nathaniel; Gildea, Richard J.; Grosse-Kunstleve, Ralf W.; Sellberg, Jonas; McQueen, Trevor A.; Fry, Alan R.; Messerschmidt, Marc M.; Miahnahri, Alan; Seibert, M. Marvin; Hampton, Christina Y.; Starodub, Dmitri; Loh, N. Duane; Sokaras, Dimosthenis; Weng, Tsu-Chien; Zwart, Petrus H.; Glatzel, Pieter; Milathianaki, Despina; White, William E.; Adams, Paul D.; Williams, Garth J.; Boutet, Sébastien; Zouni, Athina; Messinger, Johannes; Sauter, Nicholas K.; Bergmann, Uwe; Yano, Junko; Yachandra, Vittal K.; Bogan, Michael J.

    2012-01-01

    An electrospun liquid microjet has been developed that delivers protein microcrystal suspensions at flow rates of 0.14–3.1 µl min−1 to perform serial femtosecond crystallography (SFX) studies with X-ray lasers. Thermolysin microcrystals flowed at 0.17 µl min−1 and diffracted to beyond 4 Å resolution, producing 14 000 indexable diffraction patterns, or four per second, from 140 µg of protein. Nanoflow electrospinning extends SFX to biological samples that necessitate minimal sample consumption. PMID:23090408

  6. A Study on the Nuclear Foreign Policy

    International Nuclear Information System (INIS)

    Yang, Maeng Ho; Oh, K. B.; Lee, H. M.; Lee, B. W.; Ko, H. S.; Ryu, J. S.; Lee, K. S.

    2006-12-01

    In this study, the changes in international nuclear environments related to nuclear non-proliferation regimes and international nuclear cooperation activities are investigated in order to suggest recommendations for actions and measures in the national policy of Korea, focusing on the trends for strengthening international nuclear non-proliferation regimes, international discussions of multi-lateral fuel supply assurances, USA nuclear energy policy and nuclear cooperation between USA and India. International nuclear non-proliferation regime is expected to be continuously strengthened during the 21st century. Assurance of a fuel supply is a critical issue in the national nuclear power industry of Korea due to a complete dependency of its uranium enrichment services on foreign countries and the declaration of a non-possession of facilities for a uranium enrichment and nuclear reprocessing in Korea. Nuclear energy is indispensable for a national energy security and securing a competitive power of nuclear technologies, and the development and export of nuclear industry products are also very important. It is recommended to strengthen the international cooperation and diplomatic efforts of Korea for protecting the national interests in the international nuclear communities and enhancing for a national power supply as well as securing of confidence and transparency of the national nuclear policy and relevant activities

  7. Serial circulating tumour DNA analysis during multimodality treatment of locally advanced rectal cancer: a prospective biomarker study.

    Science.gov (United States)

    Tie, Jeanne; Cohen, Joshua D; Wang, Yuxuan; Li, Lu; Christie, Michael; Simons, Koen; Elsaleh, Hany; Kosmider, Suzanne; Wong, Rachel; Yip, Desmond; Lee, Margaret; Tran, Ben; Rangiah, David; Burge, Matthew; Goldstein, David; Singh, Madhu; Skinner, Iain; Faragher, Ian; Croxford, Matthew; Bampton, Carolyn; Haydon, Andrew; Jones, Ian T; S Karapetis, Christos; Price, Timothy; Schaefer, Mary J; Ptak, Jeanne; Dobbyn, Lisa; Silliman, Natallie; Kinde, Isaac; Tomasetti, Cristian; Papadopoulos, Nickolas; Kinzler, Kenneth; Volgestein, Bert; Gibbs, Peter

    2018-02-02

    For patients with locally advanced rectal cancer (LARC), adjuvant chemotherapy selection following surgery remains a major clinical dilemma. Here, we investigated the ability of circulating tumour DNA (ctDNA) to improve risk stratification in patients with LARC. We enrolled patients with LARC (T3/T4 and/or N+) planned for neoadjuvant chemoradiotherapy. Plasma samples were collected pretreatment, postchemoradiotherapy and 4-10 weeks after surgery. Somatic mutations in individual patient's tumour were identified via massively parallel sequencing of 15 genes commonly mutated in colorectal cancer. We then designed personalised assays to quantify ctDNA in plasma samples. Patients received adjuvant therapy at clinician discretion, blinded to the ctDNA results. We analysed 462 serial plasma samples from 159 patients. ctDNA was detectable in 77%, 8.3% and 12% of pretreatment, postchemoradiotherapy and postsurgery plasma samples. Significantly worse recurrence-free survival was seen if ctDNA was detectable after chemoradiotherapy (HR 6.6; Pguide patient selection for adjuvant chemotherapy. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  8. Studies on the clinical course of chronic hepatitis in the patients who underwent serial needle liver biopsies

    International Nuclear Information System (INIS)

    Hirata, Tetsuro

    1984-01-01

    In order to evaluate the changes in biochemical liver function tests and hepatic scintigraphic findings of chronic hepatitis, the author analyzed 35 patients who underwent serial liver biopsies. The results were summerized as follows: 1. Histological deteriorations in chronic hepatitis more inclined to be presented in the scintigraphic abnormalities such as the increased uptake of radioisotope in the spleen and bone marrow than the deteriorations in biochemical liver function tests. Moreover, the increased radioisotope uptake by spleen and bone marrow in hepatic scintigram highly correlated with histological deteriorations. On the other hand, in the cases with histological improvement no scintigraphic improvement was ovserved. 2. Comparing the changes in the result of liver function tests with histological features, biochemical deteriorations significantly correlated with histological deteriorations, although biochemical improvements were not reliable indicators of histological improvements. 3. Changes in biochemical parameters such as serum GOT, GPT, albumin, γ-globulin, TTT and ALP were analyzed by means of Hayashi's second method of quantification and predictive values for histological feactures were calculated. As a result, histological deteriorations were predicted in 89.5% of the cases, but histological improvements were predicted only in 66.7%. In the various biochemical parameters, γ-globulin was considered as most important in predicting histological features and ALP was ranked the second. (J.P.N.)

  9. Analysis of assembly serial number usage in domestic light-water reactors

    International Nuclear Information System (INIS)

    Reich, W.J.; Moore, R.S.

    1991-05-01

    Domestic light-water reactor (LWR) fuel assemblies are identified by a serial number that is placed on each assembly. These serial numbers are used as identifiers throughout the life of the fuel. The uniqueness of assembly serial numbers is important in determining their effectiveness as unambiguous identifiers. The purpose of this study is to determine what serial numbering schemes are used, the effectiveness of these schemes, and to quantify how many duplicate serial numbers occur on domestic LWR fuel assemblies. The serial numbering scheme adopted by the American National Standards Institute (ANSI) ensures uniqueness of assembly serial numbers. The latest numbering scheme adopted by General Electric (GE), was also found to be unique. Analysis of 70,971 fuel assembly serial numbers from permanently discharged fuel identified 11,948 serial number duplicates. Three duplicate serial numbers were found when analysis focused on duplication within the individual fuel inventory at each reactor site, but these were traced back to data entry errors and will be corrected by the Energy Information Administration (EIA). There were also three instances where the serial numbers used to identify assemblies used for hot cell studies differed from the serial numbers reported to the EIA. It is recommended that fuel fabricators and utilities adhere to the ANSI serial numbering scheme to ensure serial number uniqueness. In addition, organizations collecting serial number information, should request that all known serial numbers physically attached or associated with each assembly be reported and identified by the corresponding number scheme. 10 refs., 5 tabs

  10. A Study on the Nuclear Foreign Policy

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byung Wook; Lee, H. M.; Ko, H. S.; Ryu, J. S.; Oh, K. B.; Yang, M. H.; Lee, K. S

    2007-12-15

    This study approaches the international trends related to nuclear non-proliferation in four aspects. First, this study analyzes the trend of the international nuclear non-proliferation regime, which includes the Treaty on the Non-proliferation of Nuclear Weapons (NPT), the international nuclear export control regime and proposals for assurance of nuclear fuel supply. Second, this study analyzes the trend of international nuclear organizations, which includes the International Atomic Energy Agency (IAEA), a central body of development of nuclear technology and international nuclear diplomacy, and the Organization for Economic Co-operation and Development/Nuclear Energy Agency (OECD/NEA), a intergovernmental organization to consist of a group of nuclear advanced countries. Third, this study analyzes the trends of the U.S.'s nuclear foreign policies, particularly nuclear non-proliferation. Fourth, this study analyzes the nuclear issues of North Korea and Iran as they cause serious concerns to a international society.

  11. A Study on the Nuclear Foreign Policy

    International Nuclear Information System (INIS)

    Lee, Byung Wook; Lee, H. M.; Ko, H. S.; Ryu, J. S.; Oh, K. B.; Yang, M. H.; Lee, K. S.

    2007-12-01

    This study approaches the international trends related to nuclear non-proliferation in four aspects. First, this study analyzes the trend of the international nuclear non-proliferation regime, which includes the Treaty on the Non-proliferation of Nuclear Weapons (NPT), the international nuclear export control regime and proposals for assurance of nuclear fuel supply. Second, this study analyzes the trend of international nuclear organizations, which includes the International Atomic Energy Agency (IAEA), a central body of development of nuclear technology and international nuclear diplomacy, and the Organization for Economic Co-operation and Development/Nuclear Energy Agency (OECD/NEA), a intergovernmental organization to consist of a group of nuclear advanced countries. Third, this study analyzes the trends of the U.S.'s nuclear foreign policies, particularly nuclear non-proliferation. Fourth, this study analyzes the nuclear issues of North Korea and Iran as they cause serious concerns to a international society

  12. A Study of Philippine Monetary and Banking Policies

    OpenAIRE

    Bautista, Ernesto D.

    1992-01-01

    This study assesses the Philippine monetary and banking policies with the view of identifying preferred policy options and features of a monetary and banking policy program supportive of overall economic growth and agro-industrial development. It describes the following: the impact of existing monetary and banking policy on short- and long-term economic development and the legislative and administrative measures required to adopt and implement such a monetary and banking policy. It also ident...

  13. Cryptococcal meningitis management in Tanzania with strict schedule of serial lumber punctures using intravenous tubing sets: an operational research study.

    Science.gov (United States)

    Meda, John; Kalluvya, Samuel; Downs, Jennifer A; Chofle, Awilly A; Seni, Jeremiah; Kidenya, Benson; Fitzgerald, Daniel W; Peck, Robert N

    2014-06-01

    Cryptococcal meningitis (CM) has a mortality rate of ∼70% among HIV-infected adults in low-income countries. Controlling intracranial pressure (ICP) is essential in CM, but it is difficult in low-income countries because manometers and practical ICP management protocols are lacking. As part of a continuous quality improvement project, our Tanzanian hospital initiated a new protocol for ICP management for CM. All adult inpatients with CM are included in a prospective patient registry. At the time of analysis, this registry included data from 2 years before the initiation of this new ICP management protocol and for a 9-month period after. ICP was measured at baseline and at days 3, 7, and 14 by both manometer and intravenous (IV) tubing set. All patients were given IV fluconazole according to Tanzanian treatment guidelines and were followed until 30 days after admission. Among adult inpatients with CM, 32 of 35 patients (91%) had elevated ICP on admission. Cerebrospinal fluid pressure measurements using the improvised IV tubing set demonstrated excellent agreement (r = 0.96) with manometer measurements. Compared with historical controls, the new ICP management protocol was associated with a significant reduction in 30-day mortality (16/35 [46%] vs. 48/64 [75%] in historical controls; hazard ratio = 2.1 [95% CI: 1.1 to 3.8]; P = 0.018]. Increased ICP is almost universal among HIV-infected adults admitted with CM in Tanzania. Intensive ICP management with a strict schedule of serial lumbar punctures reduced in-hospital mortality compared with historical controls. ICP measurement with IV tubing sets may be a good alternative in resource-limited health facilities where manometers are not available.

  14. Archives: International Journal of Development and Policy Studies

    African Journals Online (AJOL)

    Archives: International Journal of Development and Policy Studies. Journal Home > Archives: International Journal of Development and Policy Studies. Log in or Register to get access to full text downloads.

  15. International Journal of Development and Policy Studies: Journal ...

    African Journals Online (AJOL)

    International Journal of Development and Policy Studies: Journal Sponsorship. Journal Home > About the Journal > International Journal of Development and Policy Studies: Journal Sponsorship. Log in or Register to get access to full text downloads.

  16. Study on defensive security concepts and policies

    International Nuclear Information System (INIS)

    1993-01-01

    The report begins by describing the background against which the proposal for the study emerged-the welcome developments brought about by the end of the cold war but also the emergence of new threats and the reappearance of long-standing problems. The study proceeds to examine current trends in the international security environment and how they may influence the peaceful settlement of dispute and the effecting of restraint and a defensive orientation in the development, maintenance and use of armed forces. A discussion of the substance and main features of defensive security concepts and policies follows. Existing studies and models designed to eliminate the offensive character of military force postures by effecting a defensive orientation of capabilities are surveyed. In addition, the study discusses political and military aspects of defensive security, pointing out how defensive security differs from those existing models

  17. A study on the nuclear foreign policy

    International Nuclear Information System (INIS)

    Oh, Keun Bae; Choi, Y. M.; Lee, D. J.; Lee, K. S.; Lee, B. W.; Ko, H. S.

    1997-12-01

    The objective of this study is to analyze and foresee the international trends related to nuclear activities, especially nuclear non-proliferation activities among others, and to suggest desirable policy direction so as to mitigate hurdles that may hinder the expansion of utilization and development of nuclear energy in Korea. This study approaches the trends of international nuclear arena in five aspects as follows. First, this study analyzes the trends of the global multilateral nuclear non-proliferation regime in Chapter II, which includes the NPT, the IAEA safeguards system, the international export control regime, the CTBT, and the treaties on nuclear weapon-free zone. Second, this study analyzes the trends of various international nuclear organizations in Chapter III, which include IAEA, OECD/NEA, and CTBTO. Third, this study reviews and analyzes regional situations in the northeast Asia surrounding Korea in Chapter IV, inter alia, pending concerns over the North Korean nuclear activities and proposed Northeast Asian nuclear cooperatively bodies such as ASIATOM, etc. Fourth, in Chapter V, this study analyzes issues concerning bilateral nuclear relationship. Especially this study analyzes nuclear cooperating agreements in general, and suggests a model agreement for the government to use when negotiating nuclear cooperation agreements with other countries. Furthermore, this study analyzes the trends of bilateral cooperation with the U.S., Canada, and Australia focusing on the standing bilateral nuclear committees. Fifth, Chapter VI especially deals with the framework of the U. S.'s nuclear non-proliferation policy, focusing on the issues such as the disposition of weapons-usable excess plutonium and the nuclear cooperation with China. (author). 44 refs., 15 tabs., 2 figs

  18. 3D reconstruction by serial sections and gas transport in a porous medium. Application to the study of a clay-loamy soil

    International Nuclear Information System (INIS)

    Cousin, Isabelle

    1996-01-01

    The transport properties of porous media like soil are clearly related to the geometrical characteristics of their porous network. The study of these geometrical properties can be divided in two parts: a morphological study (like form and size of the pores) and a topological part (pore space distribution and connectivity). The properties of gaseous diffusion in a clay-loamy soil have been studied by experiments of marked molecules ( 85 Kr) self-diffusion. The tortuosity measured in this soil core is 2.3 with a free-air porosity of 11.3 %. This soil core was then impregnated with polyester resin and ground as serial sections, 100 micrometers apart. The superimposition of the images made from these sections were characterised by stereo-logical functions (chord distributions functions and correlation functions) and by connected and percolating clusters. We showed that a 2D image, with a porosity close to the 3D reconstruction, exhibits chord distributions similar to the chord distribution of the 3D reconstruction. On the contrary, the distribution of connected clusters calculated on a 2D image and on the 3D reconstruction are different, due to the fact that the determination of connected clusters has no real stereo-logical properties. The determination of the connected clusters within the 3D reconstructed sample showed that 87.6 % of the porous network (studied at this scale) and corresponding to 17.7 % as porosity, is made of a single percolating cluster. The numerical simulation of self-diffusion propagator in the percolating system gives the tortuosity of the reconstructed system. This calculated tortuosity is equal to 1.75 and is close to the experimental tortuosity measured on the real soil sample. This low difference between the calculated and the numerical tortuosity is due to the resolution of the serial sections. This work gives also perspectives for the study of hierarchical porous media at different scales. (author) [fr

  19. Implementation of Serial and Parallel Bubble Sort on Fpga

    OpenAIRE

    Purnomo, Dwi Marhaendro Jati; Arinaldi, Ahmad; Priyantini, Dwi Teguh; Wibisono, Ari; Febrian, Andreas

    2016-01-01

    Sorting is common process in computational world. Its utilization are on many fields from research to industry. There are many sorting algorithm in nowadays. One of the simplest yet powerful is bubble sort. In this study, bubble sort is implemented on FPGA. The implementation was taken on serial and parallel approach. Serial and parallel bubble sort then compared by means of its memory, execution time, and utility which comprises slices and LUTs. The experiments show that serial bubble sort r...

  20. SERIAL TELEVISI DEXTER SEBAGAI ANAKRONISME DALAM SASTRA POPULER

    OpenAIRE

    Ida Rochani Adi

    2014-01-01

    In the popular literature context, this study aims to investigate: (1) how the formulation of the characterization of Dexter in the television serial Dexter violates the tradition of literary characterization, and (2) how the formula of moral values is dramatized through Dexter, who is a sociopath, psychopath, serial killer, and person without moral. The research object was the television serial Dexter, which ranks five in popularity in the world. The data were collected by documenting 84 epi...

  1. Representation of the serial killer on the Italian Internet.

    Science.gov (United States)

    Villano, P; Bastianoni, P; Melotti, G

    2001-10-01

    The representation of serial killers was examined from the analysis of 317 Web pages in the Italian language to study how the psychological profiles of serial killers are described on the Italian Internet. The correspondence analysis of the content of these Web pages shows that in Italy the serial killer is associated with words such as "monster" and "horror," which suggest and imply psychological perversion and aberrant acts. These traits are peculiar for the Italian scenario.

  2. [The serial murder: a few theoretical perspectives].

    Science.gov (United States)

    Leistedt, S; Linkowski, P

    2011-01-01

    Despite numbers of publications and effort to try to establish the definition, the classification, the epidemiology, the clinical aspects and the psychopathology of serial killers, a universal consensus seems to say the least. Crime, though reduced in some countries, appears to impact more and more consistent worldwide, generating controversial ideas and a multitude of possible explanations. The serial killer usually presents as a caucasian man, aged between 20 and 40 years, often embedded socially and in his family, but with serious psychiatric, personal and especially family history. Usually acting alone, the serial killer plans a crime well in advance, but sometimes within the scope of impulsivity for a minority, the victim not being previously selected. In the latter case, an actual mental illness like psychosis is found. It is clear from numerous psychopathological studies conducted so far that most serial killers are defined as psychopathic sexual sadists, whose childhood was difficult, if not flouted, punctuated by physical and psychological violence situations. In addition, pervasive fantasies combined with thoughts of death, sex and violence are as much in common with the original acts of which they are the instigators. Beyond a relentless media that is constantly watering the public with stories and pictures depicting them as such, serial killers remain an enigma. We can therefore attempt to answer the various questions raised by this phenomenon, the way these people operate and how we can curb the rise, thanks to the neurobiological and neurophysiological approaches that science offers us.

  3. Studies on the transmission of malignant catarrhal fever in experimental animals: A serial infection of cattle and buffalo by means of whole blood inoculation

    Directory of Open Access Journals (Sweden)

    Agus Wiyono

    1999-12-01

    Full Text Available Malignant catarrhal fever (MCF is a fatal disease especially affecting cattle and buffaloes. A study on the serial blood transmission of MCF was conducted by injecting whole blood of MCF animals into 9 experimental animals. Diagnosis of MCF was based on the clinico-pathological fmdings and polymerase chain reaction (PCR test. The disease has successfully, been achieved in six animals of three Bali cattle and three buffaloes but not in a Bali-cross breed and two Bos indicus (Ongole cattle. Wide range of clinical signs and gross-pathological features were observed. The study showed the degree of susceptibility of experimental animals: Bali cattle and buffalo were highly susceptible (3 out of 3 affected with MCF, Bali-cross breed and Bos indicus (Ongole cattle seemed not susceptible to whole blood experimental transmission. It shows that when Bali cattle acted as inoculum donor, buffalo tended to be clinically more severe than Bali cattle. On the other hand, when buffalo acted as inoculum donor, Bali cattle suffered from MCF more severe than buffalo. The diagnosis of MCF by histopathological examination and the PCR test bad positive correlation (100% in the first experiment, while in the second experiment the PCR test tends to be more sensitive. Based on the restriction endonuclease (RE test, the MCF causal agent in this study appeared to be genetically similar in each case. It is concluded that the serial experimental transmission of MCF by means of whole blood inoculation has been successfully achieved in Bali cattle and buffalo but not in Bali-cross breed and Ongole cattle, and there is a positive correlation between the PCR test and histopathological examination with the PCR test tends to be more sensitive.

  4. Phobic spider fear is associated with enhanced attentional capture by spider pictures: a rapid serial presentation event-related potential study.

    Science.gov (United States)

    Van Strien, Jan W; Franken, Ingmar H A; Huijding, Jorg

    2009-03-04

    The early posterior negativity (EPN) reflects early selective visual processing of emotionally significant information. This study explored the association between fear of spiders and the EPN for spider pictures. Fifty women completed a Spider Phobia Questionnaire and watched the random rapid serial presentation of 600 neutral, 600 negatively valenced emotional, and 600 spider pictures (three pictures per second). The EPN was scored as the mean activity in the 225-300-ms time window at lateral occipital electrodes. Participants with higher scores on the phobia questionnaire showed larger (i.e. more negative) EPN amplitudes in response to spider pictures. The results suggest that the attentional capture of spider-related stimuli is an automatic response, which is modulated by the extent of spider fear.

  5. Grenada School Nutrition Study: Evidence to Inform Policy | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Grenada School Nutrition Study: Evidence to Inform Policy ... LMICs can direct their efforts to changing the environments and habits that promote ... Report Card that will be suited for advocacy work, and could be used to influence policy.

  6. IMPLEMENTATION OF SERIAL AND PARALLEL BUBBLE SORT ON FPGA

    Directory of Open Access Journals (Sweden)

    Dwi Marhaendro Jati Purnomo

    2016-06-01

    Full Text Available Sorting is common process in computational world. Its utilization are on many fields from research to industry. There are many sorting algorithm in nowadays. One of the simplest yet powerful is bubble sort. In this study, bubble sort is implemented on FPGA. The implementation was taken on serial and parallel approach. Serial and parallel bubble sort then compared by means of its memory, execution time, and utility which comprises slices and LUTs. The experiments show that serial bubble sort required smaller memory as well as utility compared to parallel bubble sort. Meanwhile, parallel bubble sort performed faster than serial bubble sort

  7. A psychological profile of a serial killer: a case report.

    Science.gov (United States)

    Dogra, T D; Leenaars, Antoon A; Chadha, R K; Manju, Mehta; Lalwani, Sanjeev; Sood, Mamta; Lester, David; Raina, Anupuma; Behera, C

    2012-01-01

    Serial killers have always fascinated society. A serial killer is typically defined as a perpetrator who murders three or more people over a period of time. Most reported cases of serial killers come from the United States and Canada. In India, there are few reported cases. We present, to the best of our knowledge, the first Indian case in the literature. The present case is of a 28-year-old man, Surinder Koli. The Department of Forensic Medicine & Toxicology, All India Institute of Medical Sciences, New Delphi handled the forensic study. We present a most unique psychological investigation into the mind of a serial killer.

  8. A study on nuclear technology policy

    International Nuclear Information System (INIS)

    Yang, M. H.; Kim, H. J.; Chung, W. S.; Yun, S. W.; Kim, H. S.

    2001-01-01

    This study was carried out as a part of institutional activities of KAERI. Major research area are as follows; Future directions and effects for national nuclear R and D to be resulted from restructuring of electricity industry are studied. Comparative study was carried out between nuclear energy and other energy sources from the point of views of environmental effects by introducing life cycle assessment(LCA) method. Japanese trends of reestablishment of nuclear policy such as restructuring of nuclear administration system and long-term plan of development and use of nuclear energy are also investigated, and Russian nuclear development program and Germany trends for phase-out of nuclear electricity generation are also investigated. And trends of the demand and supply of energy in eastern asian countries in from the point of view of energy security and tension in the south china sea are analyzed and investigation of policy trends of Vietnam and Egypt for the development and use of nuclear energy for the promotion of nuclear cooperation with these countries are also carried out. Due to the lack of energy resources and high dependence of imported energy, higher priority should be placed on the use of localized energy supply technology such as nuclear power. In this connection, technological development should be strengthened positively in order to improve economy and safety of nuclear energy and proliferation resistance of nuclear fuel cycle and wide ranged use of radiation and radioisotopes and should be reflected in re-establishment of national comprehensive promotion plan of nuclear energy in progress

  9. A study on nuclear technology policy

    Energy Technology Data Exchange (ETDEWEB)

    Yang, M H; Kim, H J; Chung, W S; Yun, S W; Kim, H S

    2001-01-01

    This study was carried out as a part of institutional activities of KAERI. Major research area are as follows; Future directions and effects for national nuclear R and D to be resulted from restructuring of electricity industry are studied. Comparative study was carried out between nuclear energy and other energy sources from the point of views of environmental effects by introducing life cycle assessment(LCA) method. Japanese trends of reestablishment of nuclear policy such as restructuring of nuclear administration system and long-term plan of development and use of nuclear energy are also investigated, and Russian nuclear development program and Germany trends for phase-out of nuclear electricity generation are also investigated. And trends of the demand and supply of energy in eastern asian countries in from the point of view of energy security and tension in the south china sea are analyzed and investigation of policy trends of Vietnam and Egypt for the development and use of nuclear energy for the promotion of nuclear cooperation with these countries are also carried out. Due to the lack of energy resources and high dependence of imported energy, higher priority should be placed on the use of localized energy supply technology such as nuclear power. In this connection, technological development should be strengthened positively in order to improve economy and safety of nuclear energy and proliferation resistance of nuclear fuel cycle and wide ranged use of radiation and radioisotopes and should be reflected in re-establishment of national comprehensive promotion plan of nuclear energy in progress.

  10. THE ROMANIAN ASPECT OF THE E.U. GOVERNANCE CASE STUDIES: EDUCATUION POLICY AND ENVIRONMENTAL POLICY

    Directory of Open Access Journals (Sweden)

    OANA-ANDREEA ION

    2011-04-01

    Full Text Available This paper belongs to the domestic studies which try to connect the Romanian research to the current debates within the EU studies. The authors' aim is to analyze the aspects and the implications of the EU governance at the Member States' domestic policies level, as most of these policies are currently facing the challenges brought by the Europeanization process. Therefore, the theoretical framework selected is the theory of governance, focusing on the explanatory and analytical opportunities of two components – multi-level governance and governance networks; in this way, it is underlined the separation from the classic model of relation between the (multiplied levels of political authority (supranational, national, subnational and the exponential increase in the number and types of actors participating at the decisional process and implementation of European public policy. Within the selected case studies (environmental policy and education policy, the authors advance a research structure with the aims (a to identify the relevant actors involved in the policy-making process of these policies, at all stages of its cycle; (b to offer an explanation of the types of interactions between these actors, and (c to identify the influence these interactions exert on the communitarization pronounced tendency of some EU policy sectors. The analysis is performed in terms of the Treaty of Lisbon (the selected policies being part of distinct categories of the Union competences and it is oriented towards the national level of the making process of these policies.

  11. Serial position markers in space: visuospatial priming of serial order working memory retrieval.

    Directory of Open Access Journals (Sweden)

    Maya De Belder

    Full Text Available Most general theories on serial order working memory (WM assume the existence of position markers that are bound to the to-be-remembered items to keep track of the serial order. So far, the exact cognitive/neural characteristics of these markers have remained largely underspecified, while direct empirical evidence for their existence is mostly lacking. In the current study we demonstrate that retrieval from verbal serial order WM can be facilitated or hindered by spatial cuing: begin elements of a verbal WM sequence are retrieved faster after cuing the left side of space, while end elements are retrieved faster after cuing the right side of space. In direct complement to our previous work--where we showed the reversed impact of WM retrieval on spatial processing--we argue that the current findings provide us with a crucial piece of evidence suggesting a direct and functional involvement of space in verbal serial order WM. We outline the idea that serial order in verbal WM is coded within a spatial coordinate system with spatial attention being involved when searching through WM, and we discuss how this account can explain several hallmark observations related to serial order WM.

  12. A study on nuclear technology policy

    International Nuclear Information System (INIS)

    Kim, H. J.; Oh, K. B.; Lee, K. S.; Chung, W. S.; Lee, T. J.; Yun, S. W.; Jeong, I.

    2004-01-01

    This study was conducted as a part of institutional activities of KAERI, and the objective of the study is to survey and analyze the change of international environment in nuclear use and research and development environment, and to propose systematic alternatives on technology policy for efficiency and effectiveness of research and development through national R and D program while timely responding to the environmental change in local and global sense. Acknowledging the importance of the relationship between the external environment and the national nuclear R and D strategic planning, this study focused on the two major subjects: (1) the international environmental and technological change attached to the development of nuclear power; (2) the direction and strategy of nuclear R and D to improve effectiveness through national R and D programs as role of electricity in the future society, strategic environment of nuclear use and R and D in the future society, energy environment and nuclear technology development scenario in the future, strategic study on future vision of KAERI and technological road-mapping of national nuclear R and D for enhancing competitiveness

  13. A Descriptive Study of Music Teacher Educators' Beliefs about Policy

    Science.gov (United States)

    Aguilar, Carla E.; Richerme, Lauren Kapalka

    2016-01-01

    While policies at all levels affect music educators, and music education researchers have called for increased attention to policy issues, few have explored preservice music teacher educators' beliefs about policy. This study examined music teacher educators' (N = 81) familiarity with and attitudes toward contemporary education and music education…

  14. A study on the nuclear technology policy

    International Nuclear Information System (INIS)

    Kim, H. J.; Oh, K. B.; Chung, W. S.; Lee, T. J.; Yun, S. W.; Jeong, Ik

    2005-01-01

    This study was conducted as a part of institutional activities of KAERI, and the objective of the study is to survey and analyze the change of international environment in nuclear use and research and development environment, and to propose systematic alternatives on technology policy for efficiency and effectiveness of research and development through national R and D program while timely responding to the environmental change in local and global sense. Acknowledging the importance of the relationship between the external environment and the national nuclear R and D strategic planning for changing of environment of surrounding nuclear technology and development in the world, this study focused on the three major subjects: (1) investigation and analysis of international nuclear environmental and technological change; (2) developing nuclear R and D strategy based on the analysis of national and global environment surrounding nuclear technology development and diffusion; (3) the evaluation of role of nuclear technology and environment from the point of views of environmental effects. In order to enhance the role of national nuclear R and D program and to cope with the environmental and technological change surrounding nuclear energy, it is recommended that active participation should be done in ongoing international collaboration on future innovative nuclear technology for absorption of advanced technologies and strategic R and D planning should be centered on core technology field based on long-term vision and suggested NuTRM considering future energy-environmental surroundings for maximized use of domestic technology capabilities and resources

  15. Parliament and the making of Indian foreign policy: a study of nuclear policy

    International Nuclear Information System (INIS)

    Paranjpe, Shrikant

    1997-01-01

    This book is a study that attempts to look at the emerging role design that the Indian Parliament has come to acquire in the exercise of its functions of participating in the formulation of foreign policy. The choice of the case study of nuclear policy is deliberate in that it evokes responses in all the three important dimensions of the role of the parliament: policy-making, representational activity, and system maintenance activity. The executive and the legislature are closely associated in the process of policy-making in the Indian parliamentary set-up. The representational activities focuses on the role perception of a parliamentarian and his interest in the area of foreign policy. The system maintenance activity includes support for the regime and political system essentially ensuring continuation of policy. This book also brings out the policies as they developed and the role played by the Parliament in terms of participation in the formulation of the policies. The issue areas covered includes the scientific and technological aspects of atomic energy policy; the debate on the Nuclear Non-proliferation Treaty; peaceful nuclear explosions; and the question of the nuclear weapons option. The essential sources of the study have been parliamentary debates, published reports and other statements dealing with the topic and interviews with legislators and officials involved in the issue. Most of the recommendations and concluding observations have been based on the interviews conducted

  16. Serial analysis of gene expression (SAGE)

    NARCIS (Netherlands)

    van Ruissen, Fred; Baas, Frank

    2007-01-01

    In 1995, serial analysis of gene expression (SAGE) was developed as a versatile tool for gene expression studies. SAGE technology does not require pre-existing knowledge of the genome that is being examined and therefore SAGE can be applied to many different model systems. In this chapter, the SAGE

  17. Facial rejuvenation: Serial fat graft transfer

    African Journals Online (AJOL)

    Saad Mohamed Saad Ibrahiem

    2016-02-01

    Feb 1, 2016 ... This a clinical study carried out to test the aesthetic outcome of serial injection of the cryo-preserved fat cells for both aesthetic and reconstructive purposes. Methods: Clinical ..... ucts, devices, or drugs mentioned in this manuscript that might create a ... Adipose stem cells and regenerative medicine. 7th ed.

  18. Antisocial personality disorder, sexual sadism, malignant narcissism, and serial murder.

    Science.gov (United States)

    Geberth, V J; Turco, R N

    1997-01-01

    This paper examines the research on serial murder and its relationship to antisocial personality disorder and sexual sadism. The concept of malignant narcissism is also discussed. Case studies of serial killers are examined regarding the nature of sexual violation and crime scene behavior.

  19. The HIV, syphilis, and HCV epidemics among female sex workers in china: results from a serial cross-sectional study between 2008 and 2012.

    Science.gov (United States)

    Wang, Lu; Tang, Weiming; Wang, Lan; Qian, Shasha; Li, Yin-Ge; Xing, Jiannan; Li, Dongmin; Ding, Zhengwei; Babu, Giridhara R; Wang, Ning

    2014-07-01

    Studies on the transmission of human immunodeficiency virus (HIV) and sexually transmitted diseases in female sex workers (FSWs) have been limited primarily to inferences drawn by focusing on defined geographical areas. This serial cross-sectional study was conducted in mainland China from 2008 through 2012. Data for 827 079 participants was analyzed. We classified venues such as karaoke bars and hotels as high tier and venues such as hair salons and barbershops, massage parlors, and other public outdoor venues as low tier based on the participants' socioeconomic status. FSWs who worked at the venues and those who were present on the days of the survey were recruited. The prevalence of HIV decreased from 0.6% in 2008 to 0.3% in 2012, the syphilis prevalence ranged from 2.4% to 3.2% between 2008 and 2012, and hepatitis C virus (HCV) prevalence decreased from 0.9% in 2008 to 0.8% in 2012. Further, we found that HIV, syphilis, and HCV prevalence proportions were high in FSWs from low tiers. HIV, syphilis, and HCV prevalence among FSWs in our study decreased during the study period. Comprehensive intervention strategies, particularly those that focus on low-tier and older FSWs, are needed in order to decrease the disease burden in this population. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  20. Environmental Pricing: Studies in Policy Choices and Interactions

    DEFF Research Database (Denmark)

    areas of current practice that must be addressed. Empirical studies of policy strategies are discussed to illustrate the extent to which current climate change policy is integrated against the proposed successful policy combinations that are presented in this insightful book. Environmental pricing......Environmental taxes can be efficient tools for successful environmental policy. Their use, however, has been limited in many countries. This thoughtful book explores the scope of environmental pricing and examines a variety of national experiences in environmental policy integration, to identify...

  1. SERIAL TELEVISI DEXTER SEBAGAI ANAKRONISME DALAM SASTRA POPULER

    Directory of Open Access Journals (Sweden)

    Ida Rochani Adi

    2014-06-01

    Full Text Available In the popular literature context, this study aims to investigate: (1 how the formulation of the characterization of Dexter in the television serial Dexter violates the tradition of literary characterization, and (2 how the formula of moral values is dramatized through Dexter, who is a sociopath, psychopath, serial killer, and person without moral. The research object was the television serial Dexter, which ranks five in popularity in the world. The data were collected by documenting 84 episodes of the serial having been broadcast since 2006. They were analyzed by means of content analysis and qualitative descriptive techniques. Based on the findings, the conclusions are as follows. First, there is a violation or anachronism of characterization through the main character in the serial. Second, the dramatized moral values still contain conventional values although they are in different forms.

  2. Taxation and Skills. OECD Tax Policy Studies. No. 24

    Science.gov (United States)

    OECD Publishing, 2017

    2017-01-01

    This Tax Policy Study on Taxation and Skills examines how tax policy can encourage skills development in OECD countries. This study also assesses the returns to tertiary and adult education and examines how these returns are shared between governments and students. The study builds indicators that examine incentives for individuals and governments…

  3. Benchmarking Usage Statistics in Collection Management Decisions for Serials

    Science.gov (United States)

    Tucker, Cory

    2009-01-01

    Usage statistics are an important metric for making decisions on serials. Although the University of Nevada, Las Vegas (UNLV) Libraries have been collecting usage statistics, the statistics had not frequently been used to make decisions and had not been included in collection development policy. After undergoing a collection assessment, the…

  4. The Contribution of Short-Term Memory for Serial Order to Early Reading Acquisition: Evidence from a Longitudinal Study

    Science.gov (United States)

    Perez, Trecy Martinez; Majerus, Steve; Poncelet, Martine

    2012-01-01

    Early reading acquisition skills have been linked to verbal short-term memory (STM) capacity. However, the nature of this relationship remains controversial because verbal STM, like reading acquisition, depends on the complexity of underlying phonological processing skills. This longitudinal study addressed the relation between STM and reading…

  5. Causes of acute deterioration in patients with a ruptured intracranial aneurysm. A prospective study with serial CT scanning

    NARCIS (Netherlands)

    Vermeulen, M.; van Gijn, J.; Hijdra, A.; van Crevel, H.

    1984-01-01

    The authors studied the acute neurological deterioration in 150 patients with aneurysmal hemorrhage. These patients were closely observed for a 4-week period or until death or operation. Forty-six patients suffered a total of 62 episodes of deterioration that developed within 5 minutes after

  6. Effects of rivastigmine on visual attention in subjects with amnestic mild cognitive impairment: A serial functional MRI activation pilot-study.

    Science.gov (United States)

    Bokde, Arun L W; Cavedo, Enrica; Lopez-Bayo, Patricia; Lista, Simone; Meindl, Thomas; Born, Christine; Galluzzi, Samantha; Faltraco, Frank; Dubois, Bruno; Teipel, Stefan J; Reiser, Maximilian; Möller, Hans-Jürgen; Hampel, Harald

    2016-03-30

    A pilot study to investigate the effects of rivastigmine on the brain activation pattern due to visual attention tasks in a group of amnestic Mild Cognitive Impaired patients (aMCI). The design was an initial three-month double blind period with a rivastigmine and placebo arms, followed by a nine-month open-label period. All patients underwent serial functional magnetic resonance imaging (fMRI) at baseline, and after three and six months of follow-up. Primary endpoint was the effect of rivastigmine on functional brain changes during visual attention (face and location matching) tasks. There were five in the rivastigmine arm and two in the placebo arm. The face matching task showed higher activation of visual areas after three months of treatment but no differences compared to baseline at six months. The location matching task showed a higher activation along the dorsal visual pathway at both three and six months follow ups. Treatment with rivastigmine demonstrates a significant effect on brain activation of the dorsal visual pathway during a location matching task in patients with aMCI. Our data support the potential use of task fMRI to map specific treatment effects of cholinergic drugs during prodromal stages of Alzheimer's disease (AD). Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  7. Effect of serial infusions of reconstituted high-density lipoprotein (CER-001) on coronary atherosclerosis: rationale and design of the CARAT study.

    Science.gov (United States)

    Andrews, Jordan; Janssan, Alex; Nguyen, Tracy; Pisaniello, Anthony D; Scherer, Daniel J; Kastelein, John J P; Merkely, Bela; Nissen, Steven E; Ray, Kausik; Schwartz, Gregory G; Worthley, Stephen G; Keyserling, Connie; Dasseux, Jean-Louis; Butters, Julie; Girardi, Jacinta; Miller, Rosemary; Nicholls, Stephen J

    2017-02-01

    High-density lipoprotein (HDL) is believed to have atheroprotective properties, but an effective HDL-based therapy remains elusive. Early studies have suggested that infusion of reconstituted HDL promotes reverse cholesterol transport and vascular reactivity. The CER-001 Atherosclerosis Regression Acute Coronary Syndrome Trial (CARAT) is investigating the impact of infusing an engineered pre-beta HDL mimetic containing sphingomyelin (SM) and dipalmitoyl phosphatidlyglycerol (CER-001) on coronary atheroma volume in patients with a recent acute coronary syndrome (ACS). The CARAT is a phase 2, multicenter trial in which 292 patients with an ACS undergoing intracoronary ultrasonography and showing percent atheroma volume (PAV) greater than 30% are randomly assigned to treatment with ten infusions of CER-001 3 mg/kg or matching placebo, administered at weekly intervals. Intracoronary ultrasonography is repeated at the end of the treatment period. The primary endpoint is the nominal change in PAV. Safety and tolerability will also be evaluated. CARAT will establish whether serial 3 mg/kg infusions of an engineered pre-beta HDL mimetic containing SM and dipalmitoyl phosphatidlyglycerol (CER-001) will regress atherosclerotic plaque in patients with a recent ACS.

  8. "Am I Becoming a Serial Killer?" A Case Study of Cognitive Behavioral Therapy for Mental Illness Anxiety.

    Science.gov (United States)

    Gelinas, Bethany L; Hadjistavropoulos, Heather

    2016-05-01

    Although mental illness anxiety is described in the literature, there is very little information on which to draw when treating individuals who present with fears and worries about mental health. In fact, we identified no previous case descriptions focused on this form of anxiety and treated from a cognitive behavioral perspective. The current case study aims to advance the understanding of the clinical picture of mental illness anxiety, and facilitate the understanding of how cognitive behavioral techniques for health anxiety can be effectively adapted and implemented for such a case. A case study approach was adopted in which a baseline condition and repeated assessments were conducted during an 8-week treatment and 2-month follow-up period. In the current case study, we discuss the assessment, conceptualization, and cognitive behavioral treatment of a 24-year old woman who presented with mental illness anxiety. Several common health anxiety assessment tools and cognitive behavioural techniques were adapted for her particular clinical presentation. Consistent with research evidence for health anxiety, significant improvements in health anxiety and anxiety sensitivity were seen after eight sessions of therapy and maintained at 2-month follow-up. The results provide preliminary evidence that cognitive behavioral techniques for health anxiety can be effectively and efficiently adapted for mental illness anxiety. However, the lack of available research pertaining to mental illness anxiety contributes to challenges in conceptualization, assessment and treatment.

  9. Serial contrast-enhanced magnetic resonance and magnetization transfer in the study of patients with multiple sclerosis

    International Nuclear Information System (INIS)

    Rovira, A.; Alonso, J.; Cucurella, G.; Nos, C.; Tintore, M.; Pedraza, S.; Rio, J.; Montalban, X.

    1997-01-01

    To demonstrate the changes in the magnetization transfer ratio (MTR) of different demyelinating plaques, correlating them with the baseline values in T1-weighted contrast-enhanced magnetic resonance (MR) sequences in order to relate them more closely to the underlying disease. The study was based on 33 demyelinating plaques obtained from six patients clinically diagnosed as having remitting-recurring multiple sclerosis (MS). All the patients underwent two MR studies at a 3 to 5-month interval, including contrast-enhanced T1 and T2- weighted sequences and magnetization transfer images. The latter were used to calculate the MTR for each of the demyelinating plaques included in the study. The statistical analysis of the results obtained revealed statistically significant between initial MTR values and those of subsequent T1-weighted sequences. The MTR demonstrate significant differences between plaques according to contrast-enhanced T1-weigh tes sequences, probably indicating variable degrees of edema, demyelination and tissue destruction. These differences should be taken into account to enable the use of T1-weighted sequences to quantify the lesion load in MS patients. (Author) 35 refs

  10. Serial water changes in human skeletal muscles on exercise studied with proton magnetic resonance spectroscopy and imaging

    International Nuclear Information System (INIS)

    Ogino, Toru; Ikehira, Hiroo; Arimizu, Noboru

    1994-01-01

    In vivo 1 H-magnetic resonance imaging (MRI) enabled us to study the distribution of water in living tissues and to document changes in human skeletal muscles during physical exercise. The purpose of the present study was to determine the total muscle water changes after exercise using water in 1 H-MR spectroscopy and to compare these changes to the signal intensity change on T 2 * -weighted images and/or to the T 2 value change. Seven young male volunteers were positioned in a 1.5 T Philips MR imaging system. They were then asked to dorsiflex their ankle joint against a 2 kg weight once every 2 seconds for 2 minutes. The peak height of water declined according to the clearance curve after exercise in all seven cases with the 1 H-MRS similar to the signal intensity. The increasing rate at peak height of total muscle water exceeded both the signal intensity and the T 2 value because the water peak height on the 1 H-MRS included the extracellular water. In addition, we measured the changes in signal intensity in both calf muscles after walking race exercise. The time intensity curves were used to draw a clearance curve for each muscle group after exercise. It was possible to discern which muscle was used most from the T 2 * -weighted image that was obtained once after exercise. (author)

  11. Union Listing via OCLC's Serials Control Subsystem.

    Science.gov (United States)

    O'Malley, Terrence J.

    1984-01-01

    Describes library use of Conversion of Serials Project's (CONSER) online national machine-readable database for serials to create online union lists of serials via OCLC's Serial Control Subsystem. Problems in selection of appropriate, accurate, and authenticated records and prospects for the future are discussed. Twenty sources and sample records…

  12. NASBE Study Group Surveys State Leadership Development Policy

    Science.gov (United States)

    Newman, Bobbi; Hull, Robert

    2015-01-01

    State board members, working in partnership with the Consortium for Policy Research in Education (CPRE) at the University of Pennsylvania, conducted an in-depth study of states' school leadership development policies and practices. Data from this study are being analyzed to determine ways that states can create systems and structures for…

  13. Educational Policy Studies: Old Wine in a New Bottle.

    Science.gov (United States)

    Eisele, Chris

    1985-01-01

    As educational policy studies have multiplied, Illinois State University's (ISU) Educational Administration and Foundations Department developed a new series of policy studies grounded in historical and philosophical methodology. Content of one course is described, and benefits of the ISU model are discussed. (MT)

  14. Comparison of Monkeypox Virus Clade Kinetics and Pathology within the Prairie Dog Animal Model Using a Serial Sacrifice Study Design

    Directory of Open Access Journals (Sweden)

    Christina L. Hutson

    2015-01-01

    Full Text Available Monkeypox virus (MPXV infection of the prairie dog is valuable to studying systemic orthopoxvirus disease. To further characterize differences in MPXV clade pathogenesis, groups of prairie dogs were intranasally infected (8×103 p.f.u. with Congo Basin (CB or West African (WA MPXV, and 28 tissues were harvested on days 2, 4, 6, 9, 12, 17, and 24 postinfection. Samples were evaluated for the presence of virus and gross and microscopic lesions. Virus was recovered from nasal mucosa, oropharyngeal lymph nodes, and spleen earlier in CB challenged animals (day 4 than WA challenged animals (day 6. For both groups, primary viremia (indicated by viral DNA was seen on days 6–9 through day 17. CB MPXV spread more rapidly, accumulated to greater levels, and caused greater morbidity in animals compared to WA MPXV. Histopathology and immunohistochemistry (IHC findings, however, were similar. Two animals that succumbed to disease demonstrated abundant viral antigen in all organs tested, except for brain. Dual-IHC staining of select liver and spleen sections showed that apoptotic cells (identified by TUNEL tended to colocalize with poxvirus antigen. Interestingly splenocytes were labelled positive for apoptosis more often than hepatocytes in both MPXV groups. These findings allow for further characterization of differences between MPXV clade pathogenesis, including identifying sites that are important during early viral replication and cellular response to viral infection.

  15. Serial measurement of neuron specific enolase improves prognostication in cardiac arrest patients treated with hypothermia: A prospective study

    Directory of Open Access Journals (Sweden)

    Storm Christian

    2012-01-01

    Full Text Available Abstract Background Neuron specific enolase (NSE has repeatedly been evaluated for neurological prognostication in patients after cardiac arrest. However, it is unclear whether current guidelines for NSE cutoff levels also apply to cardiac arrest patients treated with hypothermia. Thus, we investigated the prognostic significance of absolute NSE levels and NSE kinetics in cardiac arrest patients treated with hypothermia. Methods In a prospective study of 35 patients resuscitated from cardiac arrest, NSE was measured daily for four days following admission. Outcome was assessed at ICU discharge using the CPC score. All patients received hypothermia treatment for 24 hours at 33°C with a surface cooling device according to current guidelines. Results The cutoff for absolute NSE levels in patients with unfavourable outcome (CPC 3-5 72 hours after cardiac arrest was 57 μg/l with an area under the curve (AUC of 0.82 (sensitivity 47%, specificity 100%. The cutoff level for NSE kinetics in patients with unfavourable outcome (CPC 3-5 was an absolute increase of 7.9 μg/l (AUC 0.78, sensitivity 63%, specificity 100% and a relative increase of 33.1% (AUC 0.803, sensitivity 67%, specificity 100% at 48 hours compared to admission. Conclusion In cardiac arrest patients treated with hypothermia, prognostication of unfavourable outcome by NSE kinetics between admission and 48 hours after resuscitation may be superior to prognostication by absolute NSE levels.

  16. Energy Policy Case Study - California: Renewables and Distributed Energy Resources

    Energy Technology Data Exchange (ETDEWEB)

    Homer, Juliet S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Bender, Sadie R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Weimar, Mark R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-09-19

    The purpose of this document is to present a case study of energy policies in California related to power system transformation and renewable and distributed energy resources (DERs). Distributed energy resources represent a broad range of technologies that can significantly impact how much, and when, electricity is demanded from the grid. Key policies and proceedings related to power system transformation and DERs are grouped into the following categories: 1.Policies that support achieving environmental and climate goals 2.Policies that promote deployment of DERs 3.Policies that support reliability and integration of DERs 4.Policies that promote market animation and support customer choice. Major challenges going forward are forecasting and modeling DERs, regulatory and utility business model issues, reliability, valuation and pricing, and data management and sharing.

  17. Serials Management In Polytechnic Libraries in Nigeria: A ...

    African Journals Online (AJOL)

    Serials Management In Polytechnic Libraries in Nigeria: A Comparative Study of Kaduna Polytechnic And Yaba College of Technology Libraries. ... Samaru Journal of Information Studies. Journal Home · ABOUT THIS JOURNAL · Advanced ...

  18. Impact of Serials Management, Access and Use on Publication Output of Lecturers in Nigerian Universities

    Science.gov (United States)

    Akinbode, Rahmon O. Onaolapo; Nwalo, Kenneth Ivo Ngozi

    2017-01-01

    This study investigates serials management in university libraries, determines the extent to which serials are accessed and used and appraises the influence of availability, accessibility and use of serials on publications output of lecturers in federal universities in Nigeria. Questionnaire administration method was adopted to accumulate data for…

  19. Serial powering of pixel modules

    International Nuclear Information System (INIS)

    Stockmanns, Tobias; Fischer, Peter; Huegging, Fabian; Peric, Ivan; Runolfsson, O.; Wermes, Norbert

    2003-01-01

    Modern pixel detectors for the next generation of high-energy collider experiments like LHC use readout electronics in deep sub-micron technology. Chips in this technology need a low supply voltage of 2-2.5 V alongside high current consumption to achieve the desired performance. The high supply current leads to significant voltage drops in the long and low mass supply cables so that voltage fluctuations at the chips are induced, when the supply current changes. This problem scales with the number of modules when connected in parallel to the power supplies. An alternative powering scheme connects several modules in series resulting in a higher supply voltage but a lower current consumption of the chain and therefore a much lower voltage drop in the cables. In addition the amount of cables needed to supply the detector is vastly reduced. The concept and features of serial powering are presented and studies of the implementation of this technology as an alternative for the ATLAS pixel detector are shown. In particular, it is shown that the potential risk of powering in series can be addressed and eliminated

  20. Serial powering of pixel modules

    CERN Document Server

    Stockmanns, Tobias; Hügging, Fabian Georg; Peric, I; Runólfsson, O; Wermes, Norbert

    2003-01-01

    Modern pixel detectors for the next generation of high-energy collider experiments like LHC use readout electronics in deep sub- micron technology. Chips in this technology need a low supply voltage of 2-2.5 V alongside high current consumption to achieve the desired performance. The high supply current leads to significant voltage drops in the long and low mass supply cables so that voltage fluctuations at the chips are induced, when the supply current changes. This problem scales with the number of modules when connected in parallel to the power supplies. An alternative powering scheme connects several modules in series resulting in a higher supply voltage but a lower current consumption of the chain and therefore a much lower voltage drop in the cables. In addition the amount of cables needed to supply the detector is vastly reduced. The concept and features of serial powering are presented and studies of the implementation of this technology as an alternative for the ATLAS pixel detector are shown. In par...

  1. Sexual behaviours, HIV testing, and the proportion of men at risk of transmitting and acquiring HIV in London, UK, 2000-13: a serial cross-sectional study.

    Science.gov (United States)

    Aghaizu, Adamma; Wayal, Sonali; Nardone, Anthony; Parsons, Victoria; Copas, Andrew; Mercey, Danielle; Hart, Graham; Gilson, Richard; Johnson, Anne M

    2016-09-01

    HIV incidence in men who have sex with men (MSM) in the UK has remained unchanged over the past decade despite increases in HIV testing and antiretroviral therapy (ART) coverage. In this study, we examine trends in sexual behaviours and HIV testing in MSM and explore the risk of transmitting and acquiring HIV. In this serial cross-sectional study, we obtained data from ten cross-sectional surveys done between 2000 and 2013, consisting of anonymous self-administered questionnaires and oral HIV antibody testing in MSM recruited in gay social venues in London, UK. Data were collected between October and January for all survey years up to 2008 and between February and August thereafter. All men older than 16 years were eligible to take part and fieldworkers attempted to approach all MSM in each venue and recorded refusal rates. Data were collected on demographic and sexual behavioural characteristics. We analysed trends over time using linear, logistic, and quantile regression. Of 13 861 questionnaires collected between 2000 and 2013, we excluded 1985 (124 had completed the survey previously or were heterosexual reporting no anal intercourse in the past year, and 1861 did not provide samples for antibody testing). Of the 11 876 eligible MSM recruited, 1512 (13%) were HIV positive, with no significant trend in HIV positivity over time. 35% (531 of 1505) of HIV-positive MSM had undiagnosed infection, which decreased non-linearly over time from 34% (45 of 131) to 24% (25 of 106; p=0·01), while recent HIV testing (ie, in the past year) increased from 26% (263 of 997) to 60% (467 of 777; pmove towards eradication of HIV. Public Health England. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Decoupling among CSR policies, programs, and impacts : An empirical study

    NARCIS (Netherlands)

    Graafland, Johan; Smid, Hugo

    2016-01-01

    There are relatively few empirical studies on the impacts of corporate social responsibility (CSR) policies and programs. This article addresses the research gap by analyzing the incidence of, and the conditions that affect, decoupling (defined as divergence) among CSR policies, implementation of

  3. International Journal of Development and Policy Studies - Vol 2, No ...

    African Journals Online (AJOL)

    International Journal of Development and Policy Studies - Vol 2, No 1 (2006) .... Locating oppressive use of language: a study of linguistic violence on nigerian ... trafficking - poverty link based on urban development and planning process ...

  4. Financial Inclusion and Monetary Policy: A Review of Recent Studies

    African Journals Online (AJOL)

    Ghana Journal of Development Studies ... in addition to cross-country and regional studies on the impact of financial inclusion on monetary policy using panel data. Keywords: Financial Inclusion, Financial Development, Financial Innovation, ...

  5. Serial murder: An unusual stereotype.

    Science.gov (United States)

    Sane, Mandar R; Mugadlimath, Anand B; Farooqui, Jamebaseer M; Janagond, Anand B; Mishra, Pradeep K

    2017-12-01

    Serial murders attract attention from the media, mental health experts, academia, and the general public. We present a case of serial murders that took place in a limited area and which caused public anxiety and anguish in central India. All the victims were homeless beggars, who were bludgeoned to death (crush injury). Individual murders were initially investigated by different police stations; fortunately, since they sent all the bodies to a common autopsy centre, a forensic pathologist was able to link all the cases, the first person to do so. This emphasises the need for sharing information among police stations and autopsy centres.

  6. Serial optical coherence tomography assessment of malapposed struts after everolimus-eluting stent implantation. A subanalysis from the HEAL-EES study

    Energy Technology Data Exchange (ETDEWEB)

    Ishida, Kohki [Cardiology Department, Cardiovascular Institute, Hospital Clínic, Institut d' Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona (Spain); Otsuki, Shuji [Division of Cardiology, Teikyo University Hospital, Tokyo (Japan); Giacchi, Giuseppe; Ortega-Paz, Luis [Cardiology Department, Cardiovascular Institute, Hospital Clínic, Institut d' Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona (Spain); Shiratori, Yoshitaka [Division of Cardiology, Teikyo University Hospital, Tokyo (Japan); Freixa, Xavier; Martín-Yuste, Victoria; Masotti, Mónica; Sabaté, Manel [Cardiology Department, Cardiovascular Institute, Hospital Clínic, Institut d' Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona (Spain); Brugaletta, Salvatore, E-mail: sabrugal@clinic.ub.es [Cardiology Department, Cardiovascular Institute, Hospital Clínic, Institut d' Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona (Spain)

    2017-01-15

    Background: Incomplete stent apposition (ISA) is related to stent thrombosis, which is a serious adverse event. We aim to assess the time-course of ISA after 2nd generation everolimus-eluting stent (EES) implantation. Methods: In HEAL-EES study, we enrolled 36 patients who underwent percutaneous coronary intervention (PCI) with EES. OCT imaging was performed at baseline and follow-up. Patients were randomized 1:1:1 into 3 groups according to the time in which follow-up was performed: group A (6-month), group B (9-month), and group C (12-month). In this subanalysis, patients who had ISA segments at baseline and/or follow-up OCT were analyzed. Result: At baseline, among 41 lesions in 36 patients, 20 lesions in 18 patients had ISA segments and were analyzed. At baseline, there were 3.0% ISA struts in group A (n = 8), 2.8% in group B (n = 4), and 4.5% in group C (n = 8). At follow-up, ISA struts were present in 0.09%, 0.16% and 0.64%; respectively in groups A, B, and C. At follow-up, there was a significant decrease in the frequency of ISA: group A 3.0% vs. 0.09% (p < 0.001), group B 2.8% vs. 0.16% (p < 0.001), and group C 4.5% vs. 0.64% (p < 0.001). In group A, there was one late acquired ISA at follow-up. Conclusions: In patients undergoing 2nd generation EES implantation, area of acute ISA assessed by OCT, was almost resolved at 6-month follow-up. - Highlights: • Time-course of incomplete stent apposition of everolimus-eluting stent was assessed. • Serial optical coherence tomography images at baseline and follow-up were evaluated. • Acute incomplete stent apposition was almost resolved as early as at 6 months.

  7. Influence of Spinal Manipulative Therapy Force Magnitude and Application Site on Spinal Tissue Loading: A Biomechanical Robotic Serial Dissection Study in Porcine Motion Segments.

    Science.gov (United States)

    Funabashi, Martha; Nougarou, François; Descarreaux, Martin; Prasad, Narasimha; Kawchuk, Greg

    In order to define the relation between spinal manipulative therapy (SMT) input parameters and the distribution of load within spinal tissues, the aim of this study was to determine the influence of force magnitude and application site when SMT is applied to cadaveric spines. In 10 porcine cadavers, a servo-controlled linear actuator motor provided a standardized SMT simulation using 3 different force magnitudes (100N, 300N, and 500N) to 2 different cutaneous locations: L3/L4 facet joint (FJ), and L4 transverse processes (TVP). Vertebral kinematics were tracked optically using indwelling bone pins, the motion segment removed and mounted in a parallel robot equipped with a 6-axis load cell. The kinematics of each SMT application were replicated robotically. Serial dissection of spinal structures was conducted to quantify loading characteristics of discrete spinal tissues. Forces experienced by the L3/L4 segment and spinal structures during SMT replication were recorded and analyzed. Spinal manipulative therapy force magnitude and application site parameters influenced spinal tissues loading. A significant main effect (P < .05) of force magnitude was observed on the loads experienced by the intact specimen and supra- and interspinous ligaments. The main effect of application site was also significant (P < .05), influencing the loading of the intact specimen and facet joints, capsules, and ligamentum flavum (P < .05). Spinal manipulative therapy input parameters of force magnitude and application site significantly influence the distribution of forces within spinal tissues. By controlling these SMT parameters, clinical outcomes may potentially be manipulated. Copyright © 2017. Published by Elsevier Inc.

  8. Anatomical and Physiological Changes after Paclitaxel-Coated Balloon for Atherosclerotic De Novo Coronary Lesions: Serial IVUS-VH and FFR Study.

    Directory of Open Access Journals (Sweden)

    Soe Hee Ann

    Full Text Available To assess the serial changes of de novo coronary lesions treated with paclitaxel-coated balloon (PCB using intravascular ultrasound virtual histology (IVUS-VH and fractional flow reserve (FFR.This prospective observational study enrolled 27 patients with coronary artery disease treated with PCB who underwent coronary angiography, IVUS-VH and FFR before, immediately after intervention and at 9 months. 28 de novo lesions were successfully treated with PCB. Angiographic late luminal loss was 0.02 ± 0.27 mm. Mean vessel and lumen areas showed increase at 9 months (12.0 ± 3.5 mm(2 to 13.2 ± 3.9 mm(2, p <0.001; and 5.4 ± 1.2 mm(2 to 6.5 ± 1.8 mm(2, p <0.001, respectively. Although mean plaque area was unchanged (6.6 ± 2.6 mm2 to 6.6 ± 2.4 mm(2, p = 0.269, percent atheroma volume decreased significantly (53.4 ± 7.9% to 49.5 ± 6.4%, p = 0.002. The proportion of plaque compositions including fibrous, fibrofatty, dense calcium and necrotic core by IVUS-VH was unchanged at 9 months. The FFR of the treated lesion was 0.71 ± 0.13 pre-procedure, 0.87 ± 0.06 post-procedure and 0.84 ± 0.06 at follow-up.De novo coronary lesions treated with PCB showed persistent anatomical and physiological patency with plaque redistribution and vessel remodeling without chronic elastic recoil or plaque compositional change during follow-up.

  9. State policy and teen childbearing: a review of research studies.

    Science.gov (United States)

    Beltz, Martha A; Sacks, Vanessa H; Moore, Kristin A; Terzian, Mary

    2015-02-01

    Teen childbearing is affected by many individual, family, and community factors; however, another potential influence is state policy. Rigorous studies of the relationship between state policy and teen birth rates are few in number but represent a body of knowledge that can inform policy and practice. This article reviews research assessing associations between state-level policies and teen birth rates, focusing on five policy areas: access to family planning, education, sex education, public assistance, and access to abortion services. Overall, several studies have found that measures related to access to and use of family planning services and contraceptives are related to lower state-level teen birth rates. These include adolescent enrollment in clinics, minors' access to contraception, conscience laws, family planning expenditures, and Medicaid waivers. Other studies, although largely cross-sectional analyses, have concluded that policies and practices to expand or improve public education are also associated with lower teen birth rates. These include expenditures on education, teacher-to-student ratios, and graduation requirements. However, the evidence regarding the role of public assistance, abortion access, and sex education policies in reducing teen birth rates is mixed and inconclusive. These conclusions must be viewed as tentative because of the limited number of rigorous studies that examine the relationship between state policy and teen birth rates over time. Many specific policies have only been analyzed by a single study, and few findings are based on recent data. As such, more research is needed to strengthen our understanding of the role of state policies in teen birth rates. Copyright © 2015 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  10. Serial Millisecond Crystallography of Membrane Proteins.

    Science.gov (United States)

    Jaeger, Kathrin; Dworkowski, Florian; Nogly, Przemyslaw; Milne, Christopher; Wang, Meitian; Standfuss, Joerg

    2016-01-01

    Serial femtosecond crystallography (SFX) at X-ray free-electron lasers (XFELs) is a powerful method to determine high-resolution structures of pharmaceutically relevant membrane proteins. Recently, the technology has been adapted to carry out serial millisecond crystallography (SMX) at synchrotron sources, where beamtime is more abundant. In an injector-based approach, crystals grown in lipidic cubic phase (LCP) or embedded in viscous medium are delivered directly into the unattenuated beam of a microfocus beamline. Pilot experiments show the application of microjet-based SMX for solving the structure of a membrane protein and compatibility of the method with de novo phasing. Planned synchrotron upgrades, faster detectors and software developments will go hand-in-hand with developments at free-electron lasers to provide a powerful methodology for solving structures from microcrystals at room temperature, ligand screening or crystal optimization for time-resolved studies with minimal or no radiation damage.

  11. COMPETITIVENESS ASSESSMENT OF THE REWARD POLICY: A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Ponomarchuk M. A.

    2017-09-01

    Full Text Available Competitive wage policy is considered as the main tool for solving the problem of attracting, retaining and promoting qualified personnel, which is relevant for domestic organizations. The article defines the main stages and purposes of evaluation of the competitiveness of the wage policy. The authors studied the use of an estimation of the wage policy competitiveness by the Russian organizations and identified practical need for and methods of assessing the competitiveness of the wage policy. Objective and subjective factors influencing the direction of the wage policy are identified, as well as the trends in wages under the influence of the crisis conditions. The main indicators of mobility and personnel turnover, the average wage in the Irkutsk region are considered. The description of the external conditions of functioning of the organizations in the Irkutsk region is presented.

  12. How Do We Write about Performance in Serial Television?

    OpenAIRE

    Elliott Logan

    2015-01-01

    Television studies has produced few sustained analyses of performance in serial television. Yet film studies scholarship has shown how attending to the integration of performances with other aspects of film style is crucial to the interpretation and appreciation of expression and meaning in filmed narrative fictions. However, as a particle form of filmed serial narrative, series television raises a number of questions about performance that will not necessarily be satisfyingly addressed by th...

  13. Ethics policy review: a case study in quality improvement.

    Science.gov (United States)

    Frolic, Andrea Nadine; Drolet, Katherine

    2013-02-01

    Policy work is often cited as one of the primary functions of Hospital Ethics Committees (HECs), along with consultation and education. Hospital policies can have far reaching effects on a wide array of stakeholders including, care providers, patients, families, the culture of the organisation and the community at large. In comparison with the wealth of information available about the emerging practice of ethics consultation, relatively little attention has been paid to the policy work of HECs. In this paper, we hope to advance the development of best practices in HEC policy work by describing the quality improvement process that we undertook at Hamilton Health Sciences, Hamilton, Ontario, Canada. In the first section of the paper we describe the context of our HEC policy work, and the shortcomings of our historical review process. In subsequent sections, we detail the quality improvement project we undertook in 2010, the results of the project and the specific tools we developed to enhance the quality of HEC policy work. Our goal in sharing this organisational case study is to prompt other HECs to publish qualitative descriptions of their policy work, in order to generate a body of knowledge that can inform the development of best practices for ethics policy review.

  14. Nutrition policy in whose interests? A New Zealand case study.

    Science.gov (United States)

    Jenkin, Gabrielle; Signal, Louise; Thomson, George

    2012-08-01

    In the context of the global obesity epidemic, national nutrition policies have come under scrutiny. The present paper examines whose interests - industry or public health - are served by these policies and why. Using an exemplary case study of submissions to an inquiry into obesity, the research compared the positions of industry and public health groups with that taken by government. We assessed whether the interests were given equal consideration (a pluralist model of influence) or whether the interests of one group were favoured over the other (a neo-pluralist model). 2006 New Zealand Inquiry into Obesity. Food and advertising industry and public health submitters. The Government's position was largely aligned with industry interests in three of four policy domains: the national obesity strategy; food industry policy; and advertising and marketing policies. The exception to this was nutrition policy in schools, where the Government's position was aligned with public health interests. These findings support the neo-pluralist model of interest group influence. The dominance of the food industry in national nutrition policy needs to be addressed. It is in the interests of the public, industry and the state that government regulates the food and advertising industries and limits the involvement of industry in policy making. Failure to do so will be costly for individuals, in terms of poor health and earlier death, costly to governments in terms of the associated health costs, and costly to both the government and industry due to losses in human productivity.

  15. Studying Alcohol Pricing and Taxation Policies in India | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The research team will study trends in alcohol taxation and pricing policies across 10 ... Sample Survey Office of India and the 10 state excise tax departments. ... International Water Resources Association, in close collaboration with IDRC, ...

  16. Plasma exchange combined with azathioprine in multiple sclerosis using serial gadolinium-enhanced MRI to monitor disease activity: a randomized single-masked cross-over pilot study

    DEFF Research Database (Denmark)

    Sørensen, P.S.; Wanscher, B; Szpirt, W

    1996-01-01

    the whole trial, and three patients discontinued the trial, two during the run-in period of azathioprine treatment and one at the introduction of PE. The primary efficacy variables were the number of gadolinium-enhancing lesions and the occurrence of new enhancing lesions on serial MRI performed every 3...... in the two periods. Although the total MS lesion load on MRI was significantly lower (p beneficial effect of PE or encourage a subsequent large...

  17. Fungal myositis in children: serial ultrasonographic findings

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Jung Hwa; Lee, Hee Jung; Choi, Jin Soo [Keimyung University School of Medicine, Daegu (Korea, Republic of)

    2003-08-01

    To evaluate serial ultrasonographic findings of fungal myositis in children. Eleven lesions caused by fungal myositis and occurring in six children were included in this study. Eight lesions in five children were histopathologically proven and the other three were clinically diagnosed. Serial ultrasonographic findings were retrospectively evaluated in terms of size, location, margin, internal echotexture and adjacent cortical change occurring during the follow-up period ranging from five days to two months. Three patients (50%) had multiple lesions. The sites of involvment were the thigh (n=4), calf (n=3), chest wall (n=2), abdominal wall (n=1) and forearm (n=1). Initially, diffuse muscular swelling was revealed, with ill-defined hypoechoic lesions confined to the muscle layer (n=8). Follow-up examination of eight lesions over a period of 5-10 days showed that round central echogenic lesions were surrounded by previous slightly echogenic lesions (n=6, 75%). Long-term follow-up of five lesions over a two-month period revealed periosteal thickening in one case (20%), and the peristence of echogenic solid nodules in four (80%). Pathologic examination showed that the central lesions correlated with a fungus ball and the peripheral slightly echogenic lesions corresponded to hematoma and necrosis. Serial ultrasonographic findings of fungal myositis in children revealed relatively constant features in each case. In particular, the findings of muscular necrosis and a fungus ball over a period of 5-14 days were thought to be characteristic.

  18. Fungal myositis in children: serial ultrasonographic findings

    International Nuclear Information System (INIS)

    Kwon, Jung Hwa; Lee, Hee Jung; Choi, Jin Soo

    2003-01-01

    To evaluate serial ultrasonographic findings of fungal myositis in children. Eleven lesions caused by fungal myositis and occurring in six children were included in this study. Eight lesions in five children were histopathologically proven and the other three were clinically diagnosed. Serial ultrasonographic findings were retrospectively evaluated in terms of size, location, margin, internal echotexture and adjacent cortical change occurring during the follow-up period ranging from five days to two months. Three patients (50%) had multiple lesions. The sites of involvment were the thigh (n=4), calf (n=3), chest wall (n=2), abdominal wall (n=1) and forearm (n=1). Initially, diffuse muscular swelling was revealed, with ill-defined hypoechoic lesions confined to the muscle layer (n=8). Follow-up examination of eight lesions over a period of 5-10 days showed that round central echogenic lesions were surrounded by previous slightly echogenic lesions (n=6, 75%). Long-term follow-up of five lesions over a two-month period revealed periosteal thickening in one case (20%), and the peristence of echogenic solid nodules in four (80%). Pathologic examination showed that the central lesions correlated with a fungus ball and the peripheral slightly echogenic lesions corresponded to hematoma and necrosis. Serial ultrasonographic findings of fungal myositis in children revealed relatively constant features in each case. In particular, the findings of muscular necrosis and a fungus ball over a period of 5-14 days were thought to be characteristic

  19. Empiric Study about the Mix Fiscal Policy – Economic Development

    Directory of Open Access Journals (Sweden)

    Alexandru Sergiu Ocnean

    2006-11-01

    Full Text Available Economic development is one of the primary objectives of any government. Fiscal policy represents one of the most effective tools that government authorities could use in order to influence the economy. Having this in mind, this paper focuses on the connection between economic development and fiscal policy and proposes an empirical study based on a sample of 21 European countries. Using a simple pool data model, we tried to distinguish the relations between the evolution of GDP per capita, as a proxy for economic development, and the evolution of three fiscal policy variables, namely the tax burden, the public expenditure to GDP ratio and the budget deficit to GDP ratio.

  20. Empiric Study about the Mix Fiscal Policy – Economic Development

    Directory of Open Access Journals (Sweden)

    Alexandru Sergiu Ocnean

    2006-09-01

    Full Text Available Economic development is one of the primary objectives of any government. Fiscal policy represents one of the most effective tools that government authorities could use in order to influence the economy. Having this in mind, this paper focuses on the connection between economic development and fiscal policy and proposes an empirical study based on a sample of 21 European countries. Using a simple pool data model, we tried to distinguish the relations between the evolution of GDP per capita, as a proxy for economic development, and the evolution of three fiscal policy variables, namely the tax burden, the public expenditure to GDP ratio and the budget deficit to GDP ratio.

  1. Single and Serial Fetal Biometry to Detect Preterm and Term Small- and Large-for-Gestational-Age Neonates: A Longitudinal Cohort Study

    Science.gov (United States)

    Hernandez-Andrade, Edgar; Ahn, Hyunyoung; Garcia, Maynor; Xu, Zhonghui; Korzeniewski, Steven J.; Saker, Homam; Chaiworapongsa, Tinnakorn; Hassan, Sonia S.; Yeo, Lami; Romero, Roberto

    2016-01-01

    Objectives To assess the value of single and serial fetal biometry for the prediction of small- (SGA) and large-for-gestational-age (LGA) neonates delivered preterm or at term. Methods A cohort study of 3,971 women with singleton pregnancies was conducted from the first trimester until delivery with 3,440 pregnancies (17,334 scans) meeting the following inclusion criteria: 1) delivery of a live neonate after 33 gestational weeks and 2) two or more ultrasound examinations with fetal biometry parameters obtained at ≤36 weeks. Primary outcomes were SGA (95th centile) at birth based on INTERGROWTH-21st gender-specific standards. Fetus-specific estimated fetal weight (EFW) trajectories were calculated by linear mixed-effects models using data up to a fixed gestational age (GA) cutoff (28, 32, or 36 weeks) for fetuses having two or more measurements before the GA cutoff and not already delivered. A screen test positive for single biometry was based on Z-scores of EFW at the last scan before each GA cut-off so that the false positive rate (FPR) was 10%. Similarly, a screen test positive for the longitudinal analysis was based on the projected (extrapolated) EFW at 40 weeks from all available measurements before each cutoff for each fetus. Results Fetal abdominal and head circumference measurements, as well as birth weights in the Detroit population, matched well to the INTERGROWTH-21st standards, yet this was not the case for biparietal diameter (BPD) and femur length (FL) (up to 9% and 10% discrepancy for mean and confidence intervals, respectively), mainly due to differences in the measurement technique. Single biometry based on EFW at the last scan at ≤32 weeks (GA IQR: 27.4–30.9 weeks) had a sensitivity of 50% and 53% (FPR = 10%) to detect preterm and term SGA and LGA neonates, respectively (AUC of 82% both). For the detection of LGA using data up to 32- and 36-week cutoffs, single biometry analysis had higher sensitivity than longitudinal analysis (52% vs 46

  2. Trends in unprotected intercourse among heterosexual men before and after brothel ban in Siem Reap, Cambodia: a serial cross-sectional study (2003-2012).

    Science.gov (United States)

    Wong, Mee Lian; Teo, Alvin Kuo Jing; Tai, Bee Choo; Ng, Alwyn Mao Tong; Lim, Raymond Boon Tar; Tham, Dede Kam Tyng; Kaur, Nashwinder; Tan, Rayner Kay Jin; Kros, Sarath; Touch, Savun; Chhit, Maryan; Lubek, Ian

    2018-03-27

    Following Cambodia's implementation of the 100% condom use program with enforcement of condom use and STI treatment services for sex workers in 2001, sexually transmitted infection and HIV declined markedly. In 2008, Cambodia implemented a law to ban brothel-based sex work. We reported trends in unprotected vaginal intercourse with sex workers among heterosexual men buying sex before (2003-2008) and after (2009-2012) the brothel ban in Cambodia. We also determined the association of brothel ban with these men's reports of unprotected intercourse with sex workers. In this serial cross-sectional study, we collected yearly behavioural data on random cross-sectional samples of heterosexual men buying sex who attended the only government health centre in Siem Reap for voluntary confidential counselling and testing (VCCT) between 2003 and 2012. We used multivariable Poisson regression analysis on the 10-year data of 976 men to obtain the adjusted prevalence ratio (aPR) of unprotected intercourse in the last 6 months by brothel closure. Men buying sex from non-brothel-based sex workers increased almost 3-fold from 17% in 2007-2008 before brothel closure to 55% in 2011-2012 after brothel closure (p < 0.001). Unprotected intercourse with sex workers in the last week increased significantly from 37% (2003-2004) before brothel closure to 65% (2011-2012) after brothel closure. This increase corresponded closely with the increase in self-reported unprotected intercourse from 35% to 61% by the sex workers (n = 1805) attending the same clinic for VCCT. Brothel closure was associated with an increased risk (aPR: 1.65; 95% CI: 1.40-1.94) of unprotected intercourse with sex workers. HIV prevalence in the heterosexual men declined significantly from 26% in 2003-2004 to 4.8% in 2007-2008 and 0 case in 2009-2010 before increasing to 5.6% in 2011-2012. Our findings suggest that the brothel ban had led to an increase in unprotected intercourse with all sex workers for men buying

  3. How Do We Write about Performance in Serial Television?

    Directory of Open Access Journals (Sweden)

    Elliott Logan

    2015-05-01

    Full Text Available Television studies has produced few sustained analyses of performance in serial television. Yet film studies scholarship has shown how attending to the integration of performances with other aspects of film style is crucial to the interpretation and appreciation of expression and meaning in filmed narrative fictions. However, as a particle form of filmed serial narrative, series television raises a number of questions about performance that will not necessarily be satisfyingly addressed by the direct adoption and application of approaches to writing about performance that have been honed in regard to film. How, then, do we write about performance in television serials in ways that recognise and accommodate the form’s relationship to film, while at the same time appropriately acknowledging and responding to long-form television’s serial status? To examine the difficulties and opportunities of approaching performance in serial television this way, the article conducts close readings of various pieces of television studies writing on performance, by scholars such as Jason Mittell, Sue Turnbull, George Toles, and Steven Peacock. Their work brings into view film and television’s points of common relation, and the distinctive challenges, achievements, and rewards of appreciating the best television serials, and the performances in them.

  4. Ghana Journal of Development Studies: Editorial Policies

    African Journals Online (AJOL)

    Dr. Nkegbe is Editorial Secretary and Head of Department, Department of Economics and Entrepreneurial Studies, Faculty of Integrated Development Studies, University for Development Studies. He holds a Ph.D in Agricultural and Food Economics from the University of Reading, United Kingdom. He is a Senior Lecturer in ...

  5. CASE STUDY: POLICIES, STRATEGIES AND RESPONSES TO PLAGIARISM IN SLOVAKIA

    OpenAIRE

    FOLTYNEK, Tomas; KRAVJAR, Julius; GLENDINNING, Irene

    2014-01-01

    The European project “Impact of Policies for Plagiarism in Higher Education Across Europe“ has identified best practices and gaps related to plagiarism in different European countries. Slovakia is one of interesting ones, where national repository for plagiarism detection was established. However, there are still gaps in terms of policies and overall understanding of plagiarism. This case study describes what happened in Slovakia in last few years, compares the situation with other European c...

  6. Serial blood pressure measurements

    Directory of Open Access Journals (Sweden)

    N.R. Koehler

    2002-05-01

    Full Text Available The objective of the present investigation was to study the effects of a 60-s interval of venous congestion between two noninvasive measurements of arterial blood pressure (ABP on the fluctuation of ABP, assessed by the standard deviation of the differences between two readings. ABP was measured in 345 successive patients, at rest, four times each. For 269 participants, one pair of readings was obtained with a 60-s interval and the other pair without an interval. For 76 patients, the first pair was read at the same interval, and the second pair had venous congestion interposed and there was no waiting interval. There was no increased ABP oscillation, either when there was no interval between ABP readings, or when venous congestion was interposed compared to pairs of ABP measurements performed with a 60-s interval. There was no increase in ABP oscillations when successive ABP readings were taken without an interval or even with venous congestion interposed. Contrary to the present belief, there seems to be no loss of reliability when blood pressure recordings are taken immediately one after another, in the clinical setting.

  7. Tevatron serial data repeater system

    International Nuclear Information System (INIS)

    Ducar, R.J.

    1981-01-01

    A ten megabit per second serial data repeater system has been developed for the 6.28km Tevatron accelerator. The repeaters are positioned at each of the thirty service buildings and accommodate control and abort system communications as well as distribution of the Tevatron time and energy clocks. The repeaters are transparent to the particular protocol of the transmissions. Serial data are encoded locally as unipolar two volt signals employing the self-clocking Manchester Bi-Phase code. The repeaters modulate the local signals to low-power bursts of 50 MHz rf carrier for the 260m transmission between service buildings. The repeaters also demodulate the transmission and restructure the data for local utilization. The employment of frequency discrimination techniques yields high immunity to the characteristic noise spectrum

  8. Serial Austen. Mashingups with Zombies

    Directory of Open Access Journals (Sweden)

    Eleonora Federici

    2017-01-01

    Full Text Available Jane Austen sells. She sells in all possible ways, her novels have been adapted for the cinema and the stage, they have been rewritten as comics and graphic novels. Jane austen is a cultural icon. The interest in her life is so strong that many biographies have been written in order to recover new facts and details. The places where she has lived and the places depicted in her novels have become tourist sites for literary pilgrims. Austen is a cross-over phenomenon, with regency costume balls recreated in her name and an endless proliferation of her works in all media. My essay will investigate Jane Austen and Seth Grahame-Smith’s Pride and Prejudice and Zombies (2009, a mash-up novel which has become a real cultural phenomenon of the last decade and will demonstrate how it can be considered a serial narrative. If as Henry Jenkins asserts, seriality implies the unfolding of a story over time through a process of “chunking” (that is creating meaningful parts of the same story and of “dispersal” (that is breaking the story into more parts and in more genres and media, mash-ups seems to do this.  Austen’s story remains as a “story hook” which pushes the reader to come back to different products for a continuation of the same story. So, if on the one hand, seriality occurs within the same text, the story-telling of Austen’s stories across genres and media is part of a seriality process.

  9. Notorious Cases of Serial Killers

    Directory of Open Access Journals (Sweden)

    Iosub Elena-Cătălina

    2014-05-01

    Full Text Available The reconstruction of a death scene provides an overall picture of the crime and will indicate the murder as an event or one of a series of events and also the criminal. But when the criminal is declared a serial killer, many questions are raised up. How could a person kill some else without a reason or why people react in such a disorganized way and become so brutal or what made them act like that and so many questions with also so many answers. This project explains the psychology of a murderer, his own way of thinking and acting by presuming that we may accurately discover what is in their minds when they kill. It is about a very complex issue regarding murder investigations, biological factors and psychological profile of a serial killer. Dealing with this problem we will at last reach to the question that could solve finally the puzzle: ―Are serial murderers distorted reflections of society's own values?

  10. Let's dance: Organization studies, medical sociology and health policy.

    Science.gov (United States)

    Currie, Graeme; Dingwall, Robert; Kitchener, Martin; Waring, Justin

    2012-02-01

    This Special Issue of Social Science & Medicine investigates the potential for positive inter-disciplinary interaction, a 'generative dance', between organization studies (OS), and two of the journal's traditional disciplinary foundations: health policy and medical sociology. This is both necessary and timely because of the extent to which organizations have become a neglected topic within medical sociology and health policy analysis. We argue there is need for further and more sustained theoretical and conceptual synergy between OS, medical sociology and health policy, which provides, on the one-hand a cutting-edge and thought-provoking basis for the analysis of contemporary health reforms, and on the other hand, enables the development and elaboration of theory. We emphasize that sociologists and policy analysts in healthcare have been leading contributors to our understanding of organizations in modern society, that OS enhances our understanding of medical settings, and that organizations remain one of the most influential actors of our time. As a starting point to discussion, we outline the genealogy of OS and its application to healthcare settings. We then consider how medical sociology and health policy converge or diverge with the concerns of OS in the study of healthcare settings. Following this, we focus upon the material environment, specifically the position of business schools, which frames the generative dance between OS, medical sociology and health policy. This sets the context for introducing the thirteen articles that constitute the Special Issue of Social Science & Medicine. Copyright © 2011 Elsevier Ltd. All rights reserved.

  11. Journal of Cultural Studies: Editorial Policies

    African Journals Online (AJOL)

    While it could be of natural relevance for scholars in Literary Studies, Sociology, History, Political Science, Anthropology, Fine Art, Religion and Philosophy, Linguistics, et cetera, to make contributions, it does also acknowledge that various disciplines within the sciences - management, environmental, engineering, medical, ...

  12. South African Music Studies: Editorial Policies

    African Journals Online (AJOL)

    SAMUS: South African Music Studies is the official organ for the South African Society for Research in Music (SASRIM). It gives priority to the publication of research on South African music, but continues to represent the wider field of research interests in the country and in the rest of Africa. The journal invites work from any ...

  13. Review of Southern African Studies: Editorial Policies

    African Journals Online (AJOL)

    Editorial Board. Prof. R.C. Leduka Institute of Southern African Studies, NUL. Dr. F. Baffoe Baffoe and Associates, Maseru. Prof. Q. Chakela National University of Lesotho. Prof. L.B.B.J. Machobane Machobane and Associates, Maseru. Prof. E.M. Sebatane National University of Lesotho. Dr. E. Obioha National University of ...

  14. Evaluation of School Uniform Policy in Turkey: A Case Study

    Science.gov (United States)

    Cinoglu, Mustafa

    2014-01-01

    The purpose of this study is to evaluate the results of current school uniform policies according to views of stakeholders. Descriptive case study method was used for this study to understand the concerns of the stakeholders about school uniforms. Data was collected through interviews with stakeholders and also reviewing the documents in TOKI…

  15. Preliminary Study on the Revision of Nuclear Safety Policy Statement

    International Nuclear Information System (INIS)

    Lee, Y. E.; Lee, S. H.; Chang, H. S.; Choi, K. S.; Jung, S. J.

    2011-01-01

    Nuclear safety policy in Korea is currently declared in the Nuclear Safety Charter as the highest tier document and safety principles and directions are announced in the Nuclear Safety Policy Statement. As the circumstances affecting on the nuclear safety policy change, it needs to revise the Statement. This study aims to develop the revised Nuclear Safety Policy Statement to declare that securing safety is a prerequisite to the utilization of nuclear energy, and that all workers in nuclear industry and regulatory body must adhere to the principle of priority to safety. As a result, two different types of revision are being prepared as of August. One is based on the spirit of Nuclear Safety Charter as well as the direction of future-oriented safety policies including the changes in the environment after declaration of the Statement. The other is to declare the fundamental safety objective and safety principles as the top philosophy of national nuclear safety policy by adopting the '10 Safety Principles in IAEA Safety Fundamental' instead of the current Charter. Both versions of revision are subject to further in-depth discussion. However once the revision is finalized and declared, it would be useful to accomplish effectively the organizational responsibilities and to enhance the public confidence in nuclear safety by performing the regulatory activities in a planned and systematic manner and promulgating the government's dedication to priority to safety

  16. A Study on the Nuclear Foreign Policy

    International Nuclear Information System (INIS)

    Yang, Maeng Ho; Oh, K. B.; Lee, H. M.; Lee, B. W.; Ko, H. S.; Ryu, J. S.

    2004-12-01

    It is of the utmost importance in the peaceful use and development of nuclear energy to respond in a timely manner to the changes of international nuclear communities. This study were carried focused on the trends of international movements related to nuclear non-proliferation regime and major trends in the international bi- or multi-lateral technical cooperation activities. This study investigates the major changes of international technical cooperation focusing on nuclear functional organizations, IAEA and OECD/NEA which become competent and important in the international technical cooperation. 9.11 terror and international illegal trafficking of A. Q. Khan network caused the strengthening of international nonproliferation regimes and international efforts and measures against threat of nuclear terror and this movement will kept in the international communities afterwards with GTRI, G8 action plan, UN resolution of WMD and ratification and application of additional protocol of IAEA safeguards agreement into member countries. Upgrade of nuclear diplomatic and technical networks and activities are required to secure the national rights and dignity in the international communities in effective and systematic manners through the enlarged participation and contribution of the national experts to working groups activities of IAEA and OECD/NEA together

  17. Biomass energy policy in Africa: selected case studies

    International Nuclear Information System (INIS)

    Kgathi, D.L.; Hall, D.O.; Hategeka, A.; Sekhwela, M.B.M.

    1997-01-01

    The majority of the population in the continent of Africa depend on biomass as a source of energy. Woodfuel (charcoal and fuelwood), the most important source of energy, is a subject of major concern in developing countries mainly because of its increasing scarcity, and recently because of its importance to the debate on climate change as its use is associated with emission on the greenhouse gases (GHG's). The book discusses the biomass energy problem and the policy options for addressing it in Botswana and Rwanda. Though the studies mainly draw their material from the surveys undertaken in these countries, extensive use is made of the existing general literature on this subject. The two case studies on Botswana address the nature, extent, and policy implications of the fuelwood problem, including the extent to which it contributes to deforestation. The Rwanda case studies examine the seasonal and spatial variation of the consumption of biomass energy (woodfuel and residues) and the evolution of the energy policy process with particular reference to biomass energy. A number of policy recommendations are made which may not only be relevant to Botswana and Rwanda, but also to other developing countries in a similar situation. The book thus makes a valuable contribution to the scarce literature on energy and environment in Africa. The multi-disciplinarity of the book makes it more valuable to a large number of readers. It will be an important reference material for policy makers and researchers in Africa as well as other developing countries. AFREPREN The African Energy Policy Research Network (AFREPREN) promotes research on energy issues relevant to the formulation and implementation of policy by African governments. It also aims to build research capability as well as mobilize existing expertise to address both near- and long-term challenges faced by the energy sector in Africa. (UK)

  18. The LHCb SciFi Tracker: studies on scintillating fibres and development of quality assurance procedures for the SciFi serial production

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00522744

    For 2019 an upgrade of the LHCb detector is foreseen. The tracking stations behind the magnet will be replaced by a detector made of scintillating fibres with a silicon photomultiplier read out. To achieve a spatial resolution better than 100 µm, fibres with a diameter of 250 µm are accurately positioned in several layers and glued to 2.5 m long mats. To ensure a proper quality of these fibre mats quality assurance during the production of these mats is mandatory. This thesis presents quality assurance procedures which were developed for the serial production of the Scintillating Fibre (SciFi) Tracker. In the production scintillating fibres are wound on a threaded wheel. To directly check the winding procedure, a live monitoring setup including a software based on machine learning and image recognition has been developed. The introduced quality assurance procedures enabled a smooth running serial production with high quality fibre mats. An essential parameter to assess the quality is the light yield of a fi...

  19. Studying and evaluating pharmaceutical policy--becoming a part of the policy and consultative process

    DEFF Research Database (Denmark)

    Almarsdóttir, Anna Birna; Traulsen, Janine Marie

    2006-01-01

    In this last article in the series the authors focus on the issue of researching and evaluating pharmaceutical policy. The past five articles made an argument for why pharmaceutical policy is important and why it is different from health policy. The evidence base needed for pharmaceutical policym...... culture around pharmaceutical policy. They emphasize the importance of pharmaceutical specialists' (i.e., pharmacists') involvement in pharmaceutical policy analysis and the policy consultative process....

  20. A study on enhancing policy transparency in the nuclear field

    Energy Technology Data Exchange (ETDEWEB)

    Cheon, S. W. [Korea Institute for National Unification, Seoul (Korea)

    2000-11-01

    Enhancing transparency in the nuclear field is a pending issue for the South Korea's nuclear community. International suspicions and mistrust of ROK's nuclear activities have been obstacles to the developments of South Korea's nuclear industry. South Korea's efforts have not been sufficient enough to ensure international community that its nuclear program will be used solely for peaceful purposes. Therefore, the purpose of this study is to conduct a positive and creative research on the issue of transparency and provide policy options that are conducive to developing of South Korea's nuclear industry. Based on an in-depth study on transparency of national policies, this study presents a package of detail policy measures that can contribute to enhancing transparency in the nuclear filed. 75 refs., 2 tabs. (Author)

  1. Serial position learning in honeybees.

    Directory of Open Access Journals (Sweden)

    Randolf Menzel

    Full Text Available Learning of stimulus sequences is considered as a characteristic feature of episodic memory since it contains not only a particular item but also the experience of preceding and following events. In sensorimotor tasks resembling navigational performance, the serial order of objects is intimately connected with spatial order. Mammals and birds develop episodic(-like memory in serial spatio-temporal tasks, and the honeybee learns spatio-temporal order when navigating between the nest and a food source. Here I examine the structure of the bees' memory for a combined spatio-temporal task. I ask whether discrimination and generalization are based solely on simple forms of stimulus-reward learning or whether they require sequential configurations. Animals were trained to fly either left or right in a continuous T-maze. The correct choice was signaled by the sequence of colors (blue, yellow at four positions in the access arm. If only one of the possible 4 signals is shown (either blue or yellow, the rank order of position salience is 1, 2 and 3 (numbered from T-junction. No learning is found if the signal appears at position 4. If two signals are shown, differences at positions 1 and 2 are learned best, those at position 3 at a low level, and those at position 4 not at all. If three or more signals are shown these results are corroborated. This salience rank order again appeared in transfer tests, but additional configural phenomena emerged. Most of the results can be explained with a simple model based on the assumption that the four positions are equipped with different salience scores and that these add up independently. However, deviations from the model are interpreted by assuming stimulus configuration of sequential patterns. It is concluded that, under the conditions chosen, bees rely most strongly on memories developed during simple forms of associative reward learning, but memories of configural serial patterns contribute, too.

  2. Serial Versus Direct Dilation of Small Diameter Stents Results in a More Predictable and Complete Intentional Transcatheter Stent Fracture: A PICES Bench Testing Study.

    Science.gov (United States)

    Crystal, Matthew A; Morgan, Gareth J; Danon, Saar; Gray, Robert G; Gruenstein, Daniel H; Gordon, Brent M; Goldstein, Bryan H

    2018-01-01

    Balloon-expandable stents, implanted in infants and children with congenital heart disease (CHD), often require redilation to match somatic growth. Small diameter stents may eventually require longitudinal surgical transection to prevent iatrogenic vascular stenosis. Intentional transcatheter stent fracture (TSF) is an emerging alternative approach to stent transection, but little is known about the optimal stent substrate and best protocol to improve the likelihood of successful TSF. Bench testing was performed with a stent dilation protocol. After recording baseline characteristics, stents were serially or directly dilated using ultra-high-pressure balloons (UHPB) until fracture occurred or further stent dilation was not possible. Stent characteristics recorded were as follows: cell design, metallurgy, mechanism, and uniformity of fracture. Stents tested included bare-metal coronary stents, premounted small diameter stents, and ePTFE-covered small diameter premounted stents. Ninety-four stents representing 9 distinct models were maximally dilated, with 80 (85%) demonstrating evidence of fracture. Comprehensive fracture details were recorded in 64 stents: linear and complete in 34/64 stents (53.1%), linear and incomplete in 9/64 stents (14.1%), transverse/complex and complete in 6/64 stents (9.4%), and transverse/complex and incomplete in 15/64 stents (23.4%). Stent fracture was not accomplished in some stent models secondary to significant shortening, i.e., "napkin-ring" formation. Serial dilation resulted in evidence of fracture in 62/67 (92.5%) stents compared with 18/27 (66.7%) stents in the direct dilation group (p = 0.003). Intentional TSF is feasible in an ex vivo model. Serial dilation more reliably expanded the stent and allowed for ultimate stent fracture, whereas direct large diameter dilation of stents was more likely to generate a "napkin-ring" configuration, which may be more resistant to fracture. In vivo animal and human testing is necessary to

  3. CASE STUDY: POLICIES, STRATEGIES AND RESPONSES TO PLAGIARISM IN SLOVAKIA

    Directory of Open Access Journals (Sweden)

    FOLTYNEK, Tomas

    2014-03-01

    Full Text Available The European project “Impact of Policies for Plagiarism in Higher Education Across Europe“ has identified best practices and gaps related to plagiarism in different European countries. Slovakia is one of interesting ones, where national repository for plagiarism detection was established. However, there are still gaps in terms of policies and overall understanding of plagiarism. This case study describes what happened in Slovakia in last few years, compares the situation with other European countries and discusses the results. Additionally, the number of occurrences of the terms “plagiarism” and “academic integrity” in media and on the Internet is examined in relation to recent changes.

  4. A Study of Terrorism Emergency Preparedness Policies in School Districts

    Science.gov (United States)

    Umoh, Emmanuel

    2013-01-01

    The threat of terrorism is a concern in public facilities including schools. This study focused on school districts in a southwestern state. Terrorism emergency preparedness policies are well-documented as measures to protect students and staff in school districts from terrorism threats and vulnerabilities. However, those threats and…

  5. Implementation of disability policy framework in Namibia: A qualitative study

    Directory of Open Access Journals (Sweden)

    Tonderai W. Shumba

    2018-04-01

    Conclusions: The study revealed key issues that need to be addressed in reviewing the policy and legal framework so that it is responsive to the current needs of persons with disabilities. Further, the CBR programme needs an evaluation tool to assess its effectiveness and efficiency in meeting the needs of persons with disabilities and also to elicit their experiences and satisfaction.

  6. Financial Inclusion and Monetary Policy: A Review of Recent Studies

    African Journals Online (AJOL)

    2017-05-01

    May 1, 2017 ... financial inclusion and its implications for monetary policy and financial stability. ... These studies have discussed the implications of financial exclusion for the parameters ... and allocating capital, monitoring firms and exerting corporate ... decisions, and technological innovations and hence economic ...

  7. Construction Policies on Campus An Analytical Study of the Policy of Construction Planning on Kufa Campus

    Directory of Open Access Journals (Sweden)

    Talib Hamid Altalib

    2017-06-01

    Full Text Available University Campuses, as any lively physical entity, is subject to continuous variation due to . growth, development and change. This reality covers the existing or futuristic additives or additions, consecutively these changes may have a strong sensation of disorientation as a result of formatic changes in buildings, or in movement paths. And it epitomized the research problem to "the need for knowledge to clarify the impact of intellectual and executive policy in achieving coherence, functional and space organization of the elements of the university urban environment and in the stages of future growth and change," the search targeted "to highlight the study of constraction politics on campus Bmqomadtha intellectual and executive , as well as clarify the role of the executive policy in the application of thought, "and formulated the hypothesis search " urban policy affect Bmqomadtha (intellectual and executive on the process of organizing and homogeneity of the university urban environment to make them adapted to future changes, "the University of Kufa it was chosen as the campus to represent the experimental field of research.

  8. Alternative policy study. Environment and energy in Europe and Central Asia 1990-2010. Energy-related environmental impacts of policy scenarios. GEO 2000 alternative policy study

    International Nuclear Information System (INIS)

    Van Vuuren, D.P.; Bakkes, J.A.

    2000-01-01

    The GEO-2000 study into alternative policy options for Europe and Central Asia focuses on energy use as an important driver for environmental problems across the region. The problems analyzed are climate change, acidification, summer smog, urban air pollution and risks of reactor accidents associated with nuclear power generation. The analysis includes the effects on biodiversity and population health. It considers the question of what can be achieved by moderate measures, and whether this will be enough. Similar Geo-2000 region-specific studies on alternative policies have been compiled other world regions. This report outliners the general methodology for these reports

  9. Rapid-Sequence Serial Sexual Homicides.

    Science.gov (United States)

    Schlesinger, Louis B; Ramirez, Stephanie; Tusa, Brittany; Jarvis, John P; Erdberg, Philip

    2017-03-01

    Serial sexual murderers have been described as committing homicides in a methodical manner, taking substantial time between offenses to elude the authorities. The results of our study of the temporal patterns (i.e., the length of time between homicides) of a nonrandom national sample of 44 serial sexual murderers and their 201 victims indicate that this representation may not always be accurate. Although 25 offenders (56.8%) killed with longer than a 14-day period between homicides, a sizeable subgroup was identified: 19 offenders (43.2%) who committed homicides in rapid-sequence fashion, with fewer than 14 days between all or some of the murders. Six offenders (13.6%) killed all their victims in one rapid-sequence, spree-like episode, with homicides just days apart or sometimes two murders in the same day. Thirteen offenders (29.5%) killed in one or two rapid-sequence clusters (i.e., more than one murder within a 14-day period, as well as additional homicides with greater than 14 days between each). The purpose of our study was to describe this subgroup of rapid-sequence offenders who have not been identified until now. These findings argue for accelerated forensic assessments of dangerousness and public safety when a sexual murder is detected. Psychiatric disorders with rapidly occurring symptom patterns, or even atypical mania or mood dysregulation, may serve as exemplars for understanding this extraordinary group of offenders. © 2017 American Academy of Psychiatry and the Law.

  10. Russia Foreign Policy In Latin America - Case Study Of Nicaragua

    Science.gov (United States)

    2017-05-23

    case study of Nicaragua deeper than the previous thesis. It relates a study to the larger, ongoing dialogue in the literature, filling in gaps and...RUSSIA FOREIGN POLICY IN LATIN AMERICA — CASE STUDY OF NICARAGUA A thesis presented to the Faculty of the U.S. Army Command and...countries, in which case further publication or sale of copyrighted images is not permissible. ii REPORT DOCUMENTATION PAGE Form Approved OMB No

  11. Short- and long-term memory contributions to immediate serial recognition: evidence from serial position effects.

    Science.gov (United States)

    Purser, Harry; Jarrold, Christopher

    2010-04-01

    A long-standing body of research supports the existence of separable short- and long-term memory systems, relying on phonological and semantic codes, respectively. The aim of the current study was to measure the contribution of long-term knowledge to short-term memory performance by looking for evidence of phonologically and semantically coded storage within a short-term recognition task, among developmental samples. Each experimental trial presented 4-item lists. In Experiment 1 typically developing children aged 5 to 6 years old showed evidence of phonologically coded storage across all 4 serial positions, but evidence of semantically coded storage at Serial Positions 1 and 2. In a further experiment, a group of individuals with Down syndrome was investigated as a test case that might be expected to use semantic coding to support short-term storage, but these participants showed no evidence of semantically coded storage and evidenced phonologically coded storage only at Serial Position 4, suggesting that individuals with Down syndrome have a verbal short-term memory capacity of 1 item. Our results suggest that previous evidence of semantic effects on "short-term memory performance" does not reflect semantic coding in short-term memory itself, and provide an experimental method for researchers wishing to take a relatively pure measure of verbal short-term memory capacity, in cases where rehearsal is unlikely.

  12. SMALL SERIAL AND SERIAL PRODUCTION MANAGEMENT IN UNSTABLE DEMAND ENVIROUMENT

    Directory of Open Access Journals (Sweden)

    Tsomaeva I. V.

    2014-03-01

    Full Text Available The work presents the methodological approach to production program of the enterprise serial engineering for the current period in the conditions of uncertainty of demand. Here are two problems with this. The first is connected with the formation of the production program of the next quarter, year. Objective could be to stochastic programming, but this task is difficult. Therefore, in this paper we proposed a simple solution. On the basis of statistical historical information about the deviation of actual sales data products from predicted by Monte Carlo generated a lot of production programs. Fixed worst key performance (sales, profit etc. The difference between the values of the planned target and the settlement defines stochastic reserve, to be established at the expense of additional innovations. The second problem is connected with the formation of the production program production in the planned month, taking into account the creation of stocks of production in the conditions when for a short period of time is difficult to build a pattern of change in the quantity demanded by month for serial production, as in some months of the year the products are not produced nor sold. To justify the level of inventories of finished products is information on deviations from the fact plan for past periods. Built function of frequency distribution of the values of deviations. This allows you to further build the methodology for determining the level of production (taking into account the reserves and sales of products that deliver maximum economic effect from the sales in the conditions of a random process of realization of production.

  13. The relationship between serial sexual murder and autoerotic asphyxiation.

    Science.gov (United States)

    Myers, Wade C; Bukhanovskiy, Alexandr; Justen, Elle; Morton, Robert J; Tilley, John; Adams, Kenneth; Vandagriff, Virgil L; Hazelwood, Robert R

    2008-04-07

    This case series documents and examines the association between autoerotic asphyxiation, sadomasochism, and serial sexual murderers. Autoerotic asphyxiation, along with other paraphilias found in this population, is reviewed. Five cases of serial sexual killers who engaged in autoerotic asphyxiation were identified worldwide: four from the United States and one from Russia. Case reports for each are provided. All (100%) were found to have sexual sadism in addition to autoerotic asphyxiation. Furthermore, two (40%) had bondage fetishism, and two (40%) had transvestic fetishism, consistent with these paraphilias co-occurring in those with autoerotic asphyxiation. Overall the group averaged 4.0 lifetime paraphilias. Some possible relationships were observed between the offenders' paraphilic orientation and their modus operandi, e.g., all of these serial killers strangled victims-suggesting an association between their sadistic and asphyxiative paraphilic interests. The overlap of seemingly polar opposite paraphilias in this sample--sexual sadism and autoerotic asphyxiation--is explored from a historical and clinical perspective. Multiple commonalities shared between these five offenders and serial sexual murderers in general are addressed. A primary limitation of this study is its small sample size and empirical basis; the results may not be generalizable beyond the sample. The findings from this study support the supposition that crime scene behaviors often reflect paraphilic disturbances in those who commit serial sexual homicides.

  14. A Local Dimension of Integration Policies? A Comparative Study of Berlin, Malmö, and Rotterdam

    OpenAIRE

    Dekker, Rianne; Emilsson, Henrik; Krieger, Bernhard; Scholten, Peter

    2015-01-01

    textabstractThis study examines three theses on local integration policies by a qualitative comparative case study of integration policies in three cities in three different countries (Berlin, Malmö, and Rotterdam). We found little evidence of a congruent local dimension of integration policies. Local policies resemble their national policy frameworks fairly well in terms of policy approaches and domains. Our multi-level perspective shows that this is not the result of top-down hierarchical g...

  15. Spatial serial order processing in schizophrenia.

    Science.gov (United States)

    Fraser, David; Park, Sohee; Clark, Gina; Yohanna, Daniel; Houk, James C

    2004-10-01

    The aim of this study was to examine serial order processing deficits in 21 schizophrenia patients and 16 age- and education-matched healthy controls. In a spatial serial order working memory task, one to four spatial targets were presented in a randomized sequence. Subjects were required to remember the locations and the order in which the targets were presented. Patients showed a marked deficit in ability to remember the sequences compared with controls. Increasing the number of targets within a sequence resulted in poorer memory performance for both control and schizophrenia subjects, but the effect was much more pronounced in the patients. Targets presented at the end of a long sequence were more vulnerable to memory error in schizophrenia patients. Performance deficits were not attributable to motor errors, but to errors in target choice. The results support the idea that the memory errors seen in schizophrenia patients may be due to saturating the working memory network at relatively low levels of memory load.

  16. Malingering, coaching, and the serial position effect.

    Science.gov (United States)

    Suhr, Julie A

    2002-01-01

    The normal pattern of performance on list-learning tasks is to recall more words from the beginning (primacy) and end (recency) of the list. This pattern is also seen in patients with closed head injury, but malingerers tend to recall less words from the beginning of word lists, leading to a suppressed primacy effect. The present study examined this pattern on both learning trials and delayed recall of the Auditory Verbal Learning Test (AVLT) in 34 persons performing with normal effort, 38 naive malingerers, 33 warned malingerers, and 29 head-injured patients. Both malingering groups had lower scores on the primacy portion of the list during learning trials, while normals and head-injured patients had normal serial position curves. During delayed recall, normals and head-injured patients did better than the two malingering groups on middle and recency portions of the list. Findings suggest that the serial position effect during learning trials may be a useful pattern of performance to watch for when suspicious of malingering.

  17. Policy Case Study – Food Labelling: Climate for Sustainable Growth

    OpenAIRE

    Cosbey, Aaron; Marcu, Andrei; Belis, David; Stoefs, Wijnand; Tuokko, Katja

    2015-01-01

    This study, which is part of the project entitled “Climate for Sustainable Growth“, focuses on one particular policy tool used in the agricultural sector, food labelling. It reviews food carbon labelling when put in place with clear objectives to address climate change. This study examines whether food carbon labels, as climate mitigation tools, are put in place in a sustainable way, by identifying their impacts on the three dimensions of sustainable development: 1) economic 2) social and ...

  18. How Different Forms of Policy Learning Influence Each Other: Case Studies from Austrian Innovation Policy-Making

    OpenAIRE

    Biegelbauer, Peter

    2016-01-01

    This paper investigates the question whether different forms of policy learning influence each other. The focus is on relationships between different forms of policy learning, which are explored on the basis of case study research in the field of research, technology and innovation policy-making in Austria. Methods utilised are expert interviews and document analysis besides literature and media recherché. With the goal to better understand the mechanisms behind learning processes, different ...

  19. Alternative Policy Study: Environment and energy in Europe and Central Asia 1990-2010. Energy-related environmental impacts of policy scenarios GEO-2000 alternative policy study

    NARCIS (Netherlands)

    Vuuren DP van; Bakkes JA; United Nations Environment; MNV

    2000-01-01

    The GEO-2000 study into alternative policy options for Europe and Central Asia focuses on energy use as an important driver for environmental problems across the region. The problems analyzed are climate change, acidification, summer smog, urban air pollution and risks of reactor accidents

  20. What Shapes Policy Formation in China? A Study of National Student Nutrition Policies

    Science.gov (United States)

    Liu, Ji

    2015-01-01

    This article juxtaposes "world culture" and "policy borrowing and lending" literatures to understand policy formation in China. Through reviewing China's student nutrition policy evolution since the International Conference on Nutrition in 1992 to the launch of China's landmark national rural student nutrition program in 2011,…

  1. [Policy analysis: study of public policy of environmental health in a metropolis of northeastern Brazil].

    Science.gov (United States)

    Lyra, Tereza Maciel; Araújo Júnior, José Luiz do Amaral Correa de

    2014-09-01

    The analysis of health policies has improved in Brazil despite a plethora of different methodological approaches. Based on the model developed by Walt and Gilson in 1994, the Environmental Health Program (EHP) of Recife as a policy based on the Health Promotion principles of the Unified Health System (SUS) and Agenda 21 was analyzed. An attempt was made to understand the context during the development and implementation of the EHP, the drafting process and which actors influenced the EHP agenda content and proposal. A qualitative case study was conducted, with semi-structured interviews with key actors. In terms of context, the findings include the influence of the municipal election, the socio-sanitary characteristics of Recife, the choice of the Secretary of Health and the management teams, acceptance by the technicians and the funding increase. In terms of the process, the acceptance of the managers must be stressed. Regarding the actors, the managers, sector technicians, non-sectorial actors with viability studies stood out. The content of the EHP coincided with the SUS and Health Promotion principles. Implementation was influenced by the dengue fever epidemic (2002), and cultural institutional factors that put pressure on the order of implementation of the planned actions.

  2. On the Science-Policy Bridge: Do Spatial Heat Vulnerability Assessment Studies Influence Policy?

    Directory of Open Access Journals (Sweden)

    Tanja Wolf

    2015-10-01

    Full Text Available Human vulnerability to heat varies at a range of spatial scales, especially within cities where there can be noticeable intra-urban differences in heat risk factors. Mapping and visualizing intra-urban heat vulnerability offers opportunities for presenting information to support decision-making. For example the visualization of the spatial variation of heat vulnerability has the potential to enable local governments to identify hot spots of vulnerability and allocate resources and increase assistance to people in areas of greatest need. Recently there has been a proliferation of heat vulnerability mapping studies, all of which, to varying degrees, justify the process of vulnerability mapping in a policy context. However, to date, there has not been a systematic review of the extent to which the results of vulnerability mapping studies have been applied in decision-making. Accordingly we undertook a comprehensive review of 37 recently published papers that use geospatial techniques for assessing human vulnerability to heat. In addition, we conducted an anonymous survey of the lead authors of the 37 papers in order to establish the level of interaction between the researchers as science information producers and local authorities as information users. Both paper review and author survey results show that heat vulnerability mapping has been used in an attempt to communicate policy recommendations, raise awareness and induce institutional networking and learning, but has not as yet had a substantive influence on policymaking or preventive action.

  3. On the Science-Policy Bridge: Do Spatial Heat Vulnerability Assessment Studies Influence Policy?

    Science.gov (United States)

    Wolf, Tanja; Chuang, Wen-Ching; McGregor, Glenn

    2015-10-23

    Human vulnerability to heat varies at a range of spatial scales, especially within cities where there can be noticeable intra-urban differences in heat risk factors. Mapping and visualizing intra-urban heat vulnerability offers opportunities for presenting information to support decision-making. For example the visualization of the spatial variation of heat vulnerability has the potential to enable local governments to identify hot spots of vulnerability and allocate resources and increase assistance to people in areas of greatest need. Recently there has been a proliferation of heat vulnerability mapping studies, all of which, to varying degrees, justify the process of vulnerability mapping in a policy context. However, to date, there has not been a systematic review of the extent to which the results of vulnerability mapping studies have been applied in decision-making. Accordingly we undertook a comprehensive review of 37 recently published papers that use geospatial techniques for assessing human vulnerability to heat. In addition, we conducted an anonymous survey of the lead authors of the 37 papers in order to establish the level of interaction between the researchers as science information producers and local authorities as information users. Both paper review and author survey results show that heat vulnerability mapping has been used in an attempt to communicate policy recommendations, raise awareness and induce institutional networking and learning, but has not as yet had a substantive influence on policymaking or preventive action.

  4. Effect of home-based HIV counselling and testing on stigma and risky sexual behaviours: serial cross-sectional studies in Uganda.

    Science.gov (United States)

    Nuwaha, Fred; Kasasa, Simon; Wana, Godwill; Muganzi, Elly; Tumwesigye, Elioda

    2012-06-04

    A large, district-wide, home-based HIV counselling and testing (HBHCT) programme was implemented in Bushenyi district of Uganda from 2004 to 2007. This programme provided free HBHCT services to all consenting adults of Bushenyi district and had a very high uptake and acceptability. We measured population-level changes in knowledge of HIV status, stigma and HIV-risk behaviours before and after HBHCT to assess whether widespread HBHCT had an effect on trends of risky sexual behaviours and on stigma and discrimination towards HIV. Serial cross-sectional surveys were carried out before and after the implementation of HBHCT programme in Bushenyi district of Uganda. A total of 1402 randomly selected adults (18 to 49 years) were interviewed in the baseline survey. After the implementation, a different set of randomly selected 1562 adults was interviewed using the same questionnaire. Data was collected on socio-demographic characteristics, sexual behaviour, whether respondents had ever tested for HIV and stigma and discrimination towards HIV/AIDS. The proportion of people who had ever tested for HIV increased from 18.6% to 62% (pHIV test result with a sexual partner increased from 41% to 57% (pHIV services especially in areas where access to HCT is low.

  5. Serial changes in metabolism and histology in the cold-injury trauma rat brain model. Proton magnetic resonance imaging and spectroscopy study

    Energy Technology Data Exchange (ETDEWEB)

    Kamada, Kyousuke; Houkin, Kiyohiro; Hida, Kazutoshi; Iwasaki, Yoshinobu; Abe, Hiroshi [Hokkaido Univ., Sapporo (Japan). School of Medicine

    1995-01-01

    The serial changes in metabolism and histology during the first 24 hours in the cold-injury trauma rat brain model were investigated by proton magnetic resonance (MR) imaging and high-resolution proton MR spectroscopy. Edema developed extensively via the corpus callosum in the ipsi- and contralateral hemispheres during observation as shown by gradually increased signal intensity on proton MR images. Proton MR spectroscopy showed increased levels of acetate (Ace), lactate (Lac), and glutamine (Glmi) 1 hour after lesion formation. The elevated Glmi level slightly decreased, the level of alanine (Ala) increased substantially, and that of N-acetyl-aspartate (NAA) decreased markedly after 24 hours. Increased Lac, Ace, and Ala might reflect anaerobic glycolysis associated with mitochondrial dysfunction, while decreased Glmi and NAA reveal brain tissue breakdown. The relationship between brain edema and tissue viability can be analyzed in detail using this simple traumatic model and MR techniques which will be useful in the development of therapeutic agents for brain injury. (author).

  6. Democratic Model of Public Policy Accountability. Case Study on Implementation of Street Vendors Empowerment Policy in Makassar City

    Directory of Open Access Journals (Sweden)

    Rulinawaty Kasmadsi

    2015-08-01

    Full Text Available Policy accountability is a form of manifestation of public officials responsible to the people. One form of policy accountability that is discussed here is street vendors policy accountability, because they are a group of citizens who have the economic activities in public spaces. The existence of this policy how-ever, the number of street vendors from year to year increase in Makassar City. Therefore, this study seeks to uncover and explain the democratic policy ac-countability through the street vendors’ responses and expectations to the implementation of street ven-dors empowerment policy in Makassar City; and to uncover and explain the democratic policy account-ability through the stakeholders’ responses and ex-pectations to the implementation of street vendors empowerment policy in Makassar City. To achieve these objectives, the study uses democracy theory, in which this theory focuses on togetherness in dis-cussing solutions to the various problems of street vendors and in the policy implementation as well.This study used a qualitative design and case studies strat-egy. Data collection techniques used was observa-tion, interview, and documentation. Data were ana-lyzed with case description its settings. The results of this study pointed out that the interests and needs of the street vendors are not met through the empow-erment policies vendors. This is caused by the ab-sence of accountability forum as a place of togeth-erness all of street vendors empowerment stakehold-ers’. Street vendors empowerment policy in Makassar City are designed base on a top-down approach, so they are considered as objects, which must accept all government programs aimed at them.

  7. Scientific and Technical Serials Holdings Optimization in an Inefficient Market: A LSU Serials Redesign Project Exercise.

    Science.gov (United States)

    Bensman, Stephen J.; Wilder, Stanley J.

    1998-01-01

    Analyzes the structure of the library market for scientific and technical (ST) serials. Describes an exercise aimed at a theoretical reconstruction of the ST-serials holdings of Louisiana State University (LSU) Libraries. Discusses the set definitions, measures, and algorithms necessary in the design of a computer program to appraise ST serials.…

  8. A comparison of serial order short-term memory effects across verbal and musical domains.

    Science.gov (United States)

    Gorin, Simon; Mengal, Pierre; Majerus, Steve

    2018-04-01

    Recent studies suggest that the mechanisms involved in the short-term retention of serial order information may be shared across short-term memory (STM) domains such as verbal and visuospatial STM. Given the intrinsic sequential organization of musical material, the study of STM for musical information may be particularly informative about serial order retention processes and their domain-generality. The present experiment examined serial order STM for verbal and musical sequences in participants with no advanced musical expertise and experienced musicians. Serial order STM for verbal information was assessed via a serial order reconstruction task for digit sequences. In the musical domain, serial order STM was assessed using a novel melodic sequence reconstruction task maximizing the retention of tone order information. We observed that performance for the verbal and musical tasks was characterized by sequence length as well as primacy and recency effects. Serial order errors in both tasks were characterized by similar transposition gradients and ratios of fill-in:infill errors. These effects were observed for both participant groups, although the transposition gradients and ratios of fill-in:infill errors showed additional specificities for musician participants in the musical task. The data support domain-general serial order STM effects but also suggest the existence of additional domain-specific effects. Implications for models of serial order STM in verbal and musical domains are discussed.

  9. Studying Policy Transfer through the Lens of Social Network Analysis

    DEFF Research Database (Denmark)

    Staunæs, Dorthe; Brøgger, Katja; Steiner-Khamsi, Gita

    Studying Policy Transfer through the Lens of Social Network Analysis The panelists present the findings of a joint empirical research project carried out at Aarhus University (DPU/Copenhagen) and at Teachers College, Columbia University (New York). The research project succeeded to identify...... discursive networks of political stakeholders and policy advisors that were considered key actors in the Danish school reform. The research team investigated how these networks interrelate, change over time, and represent different constituents (government, academe, business), at times contradicting...... or collaborating with each other, respectively. Against the backdrop of globalization studies in comparative education, the research project attempted to identify borrowers, translators, and brokers of educational reform drawing on a complementary set of expertise from social network analysis methodology (Oren...

  10. Numerical discrepancy between serial and MPI parallel computations

    Directory of Open Access Journals (Sweden)

    Sang Bong Lee

    2016-09-01

    Full Text Available Numerical simulations of 1D Burgers equation and 2D sloshing problem were carried out to study numerical discrepancy between serial and parallel computations. The numerical domain was decomposed into 2 and 4 subdomains for parallel computations with message passing interface. The numerical solution of Burgers equation disclosed that fully explicit boundary conditions used on subdomains of parallel computation was responsible for the numerical discrepancy of transient solution between serial and parallel computations. Two dimensional sloshing problems in a rectangular domain were solved using OpenFOAM. After a lapse of initial transient time sloshing patterns of water were significantly different in serial and parallel computations although the same numerical conditions were given. Based on the histograms of pressure measured at two points near the wall the statistical characteristics of numerical solution was not affected by the number of subdomains as much as the transient solution was dependent on the number of subdomains.

  11. Trade liberalization, social policies and health: an empirical case study.

    Science.gov (United States)

    McNamara, Courtney

    2015-10-12

    This study investigates the health impacts of a major liberalization episode in the textile and clothing (T&C) sector. This episode triggered substantial shifts in employment across a wide range of countries. It is the first study to empirically link trade liberalization to health via changes in employment and offers some of the first empirical insights on how trade liberalization interacts with social policies to influence health. Data from 32 T&C reliant countries were analysed in reference to the pre- and post-liberalization periods of 2000-2004 and 2005-2009. Fuzzy-set qualitative comparative analysis (fsQCA) was used to examine the association between countries' a) level of development b) labour market and welfare state protections c) T&C employment changes and d) changes in adult female and infant mortality rates. Process tracing was used to further investigate these associations through twelve in-depth country studies. Results from the fsQCA relate changes in employment after the phase-out to both changing adult female and infant mortality rates. Findings from the in-depth country studies suggest that the worsening of adult female mortality rates is related to workers' lack of social protection, both in the context of T&C employment growth and loss. Overall, it is found that social protection is often inaccessible to the type of workers who may be the most vulnerable to processes of liberalization and that many workers are particularly vulnerable due to the structure of social protection policies. Social policies are therefore found to both moderate pathways to health and influence the type of health-related pathways resulting from trade liberalizing policies.

  12. Serial Position Functions in General Knowledge

    Science.gov (United States)

    Kelley, Matthew R.; Neath, Ian; Surprenant, Aimée M.

    2015-01-01

    Serial position functions with marked primacy and recency effects are ubiquitous in episodic memory tasks. The demonstrations reported here explored whether bow-shaped serial position functions would be observed when people ordered exemplars from various categories along a specified dimension. The categories and dimensions were: actors and age;…

  13. The Serial Murderer's Motivations: An Interdisciplinary Review.

    Science.gov (United States)

    DeHart, Dana D.; Mahoney, John M.

    1994-01-01

    Defines serial killer as individual who murders two or more victims over an extended period of time, ranging from days to years, with the crimes often being sexually motivated. Reviews existing motivational theories of serial murder and proposes additional explications from range of disciplines. Presents suggestions for future research and…

  14. Modus operandi of female serial killers.

    Science.gov (United States)

    Wilson, W; Hilton, T

    1998-04-01

    The modus operandi of female serial killers was examined from a chronology of 58 cases in America and 47 cases in 17 other countries, compiled over 25-year intervals. Female serial killers in other countries accounted for a disproportionately greater number of victims, but those in America managed a longer killing career when associated with a low profile modus operandi.

  15. Female serial killing: review and case report.

    Science.gov (United States)

    Frei, Andreas; Völlm, Birgit; Graf, Marc; Dittmann, Volker

    2006-01-01

    Single homicide committed by women is rare. Serial killing is very infrequent, and the perpetrators are usually white, intelligent males with sadistic tendencies. Serial killing by women has, however, also been described. To conduct a review of published literature on female serial killers and consider its usefulness in assessing a presenting case. A literature review was conducted, after searching EMBASE, MEDLINE and PsycINFO. The presenting clinical case is described in detail in the context of the literature findings. Results The literature search revealed few relevant publications. Attempts to categorize the phenomenon of female serial killing according to patterns of and motives for the homicides have been made by some authors. The most common motive identified was material gain or similar extrinsic gratification while the 'hedonistic' sadistic or sexual serial killer seems to be extremely rare in women. There is no consistent theory of serial killing by women, but psychopathic personality traits and abusive childhood experiences have consistently been observed. The authors' case did not fit the description of a 'typical' female serial killer. In such unusual circumstances as serial killing by a woman, detailed individual case formulation is required to make sense of the psychopathology in each case. Publication of cases in scientific journals should be encouraged to advance our understanding of this phenomenon. Copyright (c) 2006 John Wiley & Sons, Ltd.

  16. Asymmetric binding in serial memory for verbal and spatial information

    NARCIS (Netherlands)

    Guerard, Katherine; Morey, Candice C.; Lagace, Sebastien; Tremblay, Sebastien

    As the number of studies showing that items can be retained as bound representations in memory increases, researchers are beginning to investigate how the different features are bound together. In the present study, we examined the relative importances of the verbal and spatial features in serial

  17. Using identification in entertainment-education drama serials to ...

    African Journals Online (AJOL)

    The study used two entertainment-education drama serials which were designed using Albert Bandura's theoretical framework to communicate positive messages of women's rights to real life audiences in select communities. The study sought to find out if there was any significant relationship i.e. identification between TV ...

  18. Handling uncertainty in bioenergy policy design – A case study analysis of UK and German bioelectricity policy instruments

    International Nuclear Information System (INIS)

    Purkus, Alexandra; Röder, Mirjam; Gawel, Erik; Thrän, Daniela; Thornley, Patricia

    2015-01-01

    In designing policies to promote bioenergy, policy makers face challenges concerning uncertainties about the sustainability of bioenergy pathways (including greenhouse gas balances), technology and resource costs, or future energy market framework conditions. New information becomes available with time, but policy adjustments can involve high levels of adaptation costs. To enable an effective steering of technology choices and innovation, policies have to strike a balance between creating a consistent institutional framework, which establishes planning security for investors, and sufficient flexibility to adapt to new information. This paper examines implications of economic theory for handling cost and benefit uncertainty in bioelectricity policy design, focussing on choices between price and quantity instruments, technology differentiation, and policy adjustment. Findings are applied to two case studies, the UK's Renewables Obligation and the German feed-in tariff/feed-in premium scheme. Case study results show the trade-offs that are involved in instrument choice and design – depending on political priorities and a country's specific context, different options can prove more adequate. Combining market-based remuneration with sustainability criteria results in strong incentives for bioenergy producers to search for low-cost solutions; whereas cost-based price instruments with centrally steered technology and feedstock choices offer higher planning security for investors and more direct control for policy makers over what pathways are implemented. Independent of the choice of instrument type and technology differentiation mechanism, findings emphasise the importance of a careful policy design, which determines the exact balance between performance criteria such as cost control, incentive intensity, planning security and adaptive efficiency. - Highlights: • Bioelectricity policy design must deal with simultaneous cost and benefit uncertainty.

  19. Serial binary interval ratios improve rhythm reproduction.

    Science.gov (United States)

    Wu, Xiang; Westanmo, Anders; Zhou, Liang; Pan, Junhao

    2013-01-01

    Musical rhythm perception is a natural human ability that involves complex cognitive processes. Rhythm refers to the organization of events in time, and musical rhythms have an underlying hierarchical metrical structure. The metrical structure induces the feeling of a beat and the extent to which a rhythm induces the feeling of a beat is referred to as its metrical strength. Binary ratios are the most frequent interval ratio in musical rhythms. Rhythms with hierarchical binary ratios are better discriminated and reproduced than rhythms with hierarchical non-binary ratios. However, it remains unclear whether a superiority of serial binary over non-binary ratios in rhythm perception and reproduction exists. In addition, how different types of serial ratios influence the metrical strength of rhythms remains to be elucidated. The present study investigated serial binary vs. non-binary ratios in a reproduction task. Rhythms formed with exclusively binary (1:2:4:8), non-binary integer (1:3:5:6), and non-integer (1:2.3:5.3:6.4) ratios were examined within a constant meter. The results showed that the 1:2:4:8 rhythm type was more accurately reproduced than the 1:3:5:6 and 1:2.3:5.3:6.4 rhythm types, and the 1:2.3:5.3:6.4 rhythm type was more accurately reproduced than the 1:3:5:6 rhythm type. Further analyses showed that reproduction performance was better predicted by the distribution pattern of event occurrences within an inter-beat interval, than by the coincidence of events with beats, or the magnitude and complexity of interval ratios. Whereas rhythm theories and empirical data emphasize the role of the coincidence of events with beats in determining metrical strength and predicting rhythm performance, the present results suggest that rhythm processing may be better understood when the distribution pattern of event occurrences is taken into account. These results provide new insights into the mechanisms underlining musical rhythm perception.

  20. Serial binary interval ratios improve rhythm reproduction

    Directory of Open Access Journals (Sweden)

    Xiang eWu

    2013-08-01

    Full Text Available Musical rhythm perception is a natural human ability that involves complex cognitive processes. Rhythm refers to the organization of events in time, and musical rhythms have an underlying hierarchical metrical structure. The metrical structure induces the feeling of a beat and the extent to which a rhythm induces the feeling of a beat is referred to as its metrical strength. Binary ratios are the most frequent interval ratio in musical rhythms. Rhythms with hierarchical binary ratios are better discriminated and reproduced than rhythms with hierarchical non-binary ratios. However, it remains unclear whether a superiority of serial binary over non-binary ratios in rhythm perception and reproduction exists. In addition, how different types of serial ratios influence the metrical strength of rhythms remains to be elucidated. The present study investigated serial binary vs. non-binary ratios in a reproduction task. Rhythms formed with exclusively binary (1:2:4:8, non-binary integer (1:3:5:6, and non-integer (1:2.3:5.3:6.4 ratios were examined within a constant meter. The results showed that the 1:2:4:8 rhythm type was more accurately reproduced than the 1:3:5:6 and 1:2.3:5.3:6.4 rhythm types, and the 1:2.3:5.3:6.4 rhythm type was more accurately reproduced than the 1:3:5:6 rhythm type. Further analyses showed that reproduction performance was better predicted by the distribution pattern of event occurrences within an inter-beat interval, than by the coincidence of events with beats, or the magnitude and complexity of interval ratios. Whereas rhythm theories and empirical data emphasize the role of the coincidence of events with beats in determining metrical strength and predicting rhythm performance, the present results suggest that rhythm processing may be better understood when the distribution pattern of event occurrences is taken into account. These results provide new insights into the mechanisms underlining musical rhythm perception.

  1. A study on the nuclear foreign policy analysis

    International Nuclear Information System (INIS)

    Oh, Keun Bae; Choi, Y. M.; Lee, D. J.; Lee, K. S.; Lee, B. W.; Cho, I. H.; Ko, H. S.

    1996-12-01

    This study aims to analyses recent trends of international situation relating to nuclear non-proliferation and the adverse conditions in Korea's pursuing self-support of such technology, so that it may map out effective strategies for the promotion of nuclear energy. This study analyses developments of international nuclear non-proliferation regime, which plays a main role in preventing the international proliferation of nuclear weapons. This study includes NPT, IAEA safeguards system, international export control regimes, CTBT, and NWFZs as the subjects of analysis. Second theme is international organizations concerning nuclear activities. This study mainly analyses IAEA activities which pursues the promotion of peaceful use of nuclear energy and nuclear non-proliferation simultaneously as a pivotal body of international nuclear cooperation. Third focus of this study is Northeast Asian circumstances pertaining to nuclear non-proliferation. The study looks into the DPRK nuclear issues, and reviews the developments of the proposed regional body for nuclear cooperation and the discussion on the Northeast Asian NWFZ. Fourth, but the most influential to Korean nuclear activities, is the U. S. nuclear policy, since U. S. takes the overwhelming initiative in the field of international nuclear non-proliferation. Therefore, this study gives much weight in analyzing the structure, procedures, recent trend, and pending issues of U. S. nuclear policy. (author). 78 refs., 5 tabs., 4 figs

  2. Qualitative methods for the study of policy diffusion

    DEFF Research Database (Denmark)

    Starke, Peter

    2013-01-01

    This article deals with the question whether and how processes of policy diffusion can be examined with qualitative methods. More specifically, how can qualitative methods address the “twin challenge of interdependence,” namely the challenge to identify diffusion, on the one hand, and the challen...... closes with some suggestions for further methodological development in the study of policy diffusion, including the combination of quantitative and qualitative methods.......This article deals with the question whether and how processes of policy diffusion can be examined with qualitative methods. More specifically, how can qualitative methods address the “twin challenge of interdependence,” namely the challenge to identify diffusion, on the one hand, and the challenge...... to discriminate between mechanisms of diffusion, on the other? I argue, first, that there are three distinct qualitative techniques that can be used, namely cross-case analysis (often based on systematic case selection), within-case process tracing, and counterfactual reasoning. I demonstrate how these techniques...

  3. Transversing the Vertical Case Study: A Methodological Approach to Studies of Educational Policy as Practice

    Science.gov (United States)

    Bartlett, Lesley; Vavrus, Frances

    2014-01-01

    How can scholars trace the global production and circulation of educational policies? The vertical case study incorporates three elements: "vertical" attention across micro-, meso-, and macro-levels, or scales; a "horizontal" comparison of how policies unfold in distinct locations; and a "transversal," processual…

  4. 3D Topography of the Young Adult Anal Sphincter Complex Reconstructed from Undeformed Serial Anatomical Sections

    NARCIS (Netherlands)

    Wu, Yi; Dabhoiwala, Noshir F.; Hagoort, Jaco; Shan, Jin-Lu; Tan, Li-Wen; Fang, Bin-Ji; Zhang, Shao-Xiang; Lamers, Wouter H.

    2015-01-01

    Pelvic-floor anatomy is usually studied by artifact-prone dissection or imaging, which requires prior anatomical knowledge. We used the serial-section approach to settle contentious issues and an interactive 3D-pdf to make the results widely accessible. 3D reconstructions of undeformed thin serial

  5. Serial MR findings of metaphyseal cyst in Legg-Calve-Perthes disease: a case report

    International Nuclear Information System (INIS)

    Shim, Chang Min; Na, Jae Boem; Moon, Haeng Jin

    2001-01-01

    Metaphyseal cysts are common findings in Lee-Calve-Perthes(LCP) disease, though usually disappear within 6-12 months several studies have described the MR imaging findings of these cysts, though serial MRI findings have not been documented. In this report, therefore, we report the serial MRI results of metaphyseal cyst in LCP patients

  6. Serial cranial ultrasonography or early MRI for detecting preterm brain injury?

    NARCIS (Netherlands)

    Plaisier, Annemarie; Raets, Marlou M A; Ecury-Goossen, Ginette M; Govaert, Paul; Feijen-Roon, Monique; Reiss, Irwin K M; Smit, Liesbeth S; Lequin, Maarten H; Dudink, Jeroen

    OBJECTIVE: To investigate detection ability and feasibility of serial cranial ultrasonography (CUS) and early MRI in preterm brain injury. DESIGN: Prospective cohort study. SETTING: Level III neonatal intensive care unit. PATIENTS: 307 infants, born below 29 weeks of gestation. METHODS: Serial CUS

  7. Serial CT scannings in herpes simplex encephalitis

    Energy Technology Data Exchange (ETDEWEB)

    Fukushima, M.; Sawada, T.; Kuriyama, Y.; Kinugawa, H.; Yamaguchi, T. (National Cardivascular Center, Osaka (Japan))

    1981-10-01

    Two patients with serologically confirmed herpes simplex encephalitis were studied by serial CT scannings. Case 1, a 60-year-old woman, was admitted to National Cardiovascular Center because of headache, fever, and attacks of Jacksonian seizure. Case 2, a 54-year-old man, was admitted because of fever, consciousness disturbance and right hemiparesis. Pleocytosis (mainly lymphocytes) and elevation of protein content in cerebrospinal fluid were observed in both cases. Both patients presented ''das apallische Syndrom'' one month after admission. The diagnosis of herpes simplex encephalitis was confirmed by typical clinical courses and by greater than fourfold rises in serum antibody titer for herpes simplex virus as well as that in cerebrospinal fluid in case 1. Characteristic CT findings observed in these two cases were summarized as follows: Within a week after the onset, no obvious abnormalities could be detected on CT scans (Case 1). Two weeks after the onset, a large low-density area appeared in the left temporal lobe and in the contralateral insular cortex with midline shift toward the right side (Case 2). One month later, an ill-defined linear and ring-like high-density area (Case 1), or a well-defined high-density area (Case 2), that was enhanced after contrast administration, was observed in the large low-density area in the temporal lobe. These findings were considered as characteristic for hemorrhagic encephalitis. These high-density areas disappeared two months later, however, widespread and intensified low-density areas still remained. In both cases, the basal ganglia and thalamus were completely spared on CT scans. From these observations, it can be concluded that serial CT scannings are quite useful for diagnosis of herpes simplex encephalitis.

  8. Serial CT scannings in herpes simplex encephalitis

    International Nuclear Information System (INIS)

    Fukushima, Masashi; Sawada, Tohru; Kuriyama, Yoshihiro; Kinugawa, Hidekazu; Yamaguchi, Takenori

    1981-01-01

    Two patients with serologically confirmed herpes simplex encephalitis were studied by serial CT scannings. Case 1, a 60-year-old woman, was admitted to National Cardiovascular Center because of headache, fever, and attacks of Jacksonian seizure. Case 2, a 54-year-old man, was admitted because of fever, consciousness disturbance and right hemipare sis. Pleocytosis (mainly lymphocytes) and elevation of protein content in cerebrospinal fluid were observed in both cases. Both patients presented ''das apallische Syndrom'' one month after admission. The diagnosis of herpes simplex encephalitis was confirmed by typical clinical courses and by greater than fourfold rises in serum antibody titer for herpes simplex virus as well as that in cerebrospinal fluid in case 1. Characteristic CT findings observed in these two cases were summarized as follows: Within a week after the onset, no obvious abnormalities could be detected on CT scans (Case 1). Two weeks after the onset, a large low-density area appeared in the left temporal lobe and in the contralateral insular cortex with midline shift toward the right side (Case 2). One month later, an ill-defined linear and ring-like high-density area (Case 1), or a well-defined high-density area (Case 2), that was enhanced after contrast administration, was observed in the large low-density area in the temporal lobe. These findings were considered as characteristic for hemorrhagic encephalitis. These high-density areas disappeared two months later, however, widespread and intensified low-density areas still remained. In both cases, the basal ganglia and thalamus were completely spared on CT scans. From these observations, it can be concluded that serial CT scannings are quite useful for diagnosis of herpes simplex encephalitis. (author)

  9. PORNOGRAFI DALAM SERIAL ANIME ANAK (ANALISIS SEMIOTIKA DALAM SERIAL CRAYON SHIN CHAN

    Directory of Open Access Journals (Sweden)

    - Sangidun

    2017-01-01

    Full Text Available Crayon Shin Chan, a Japanese two-dimension animation series broadcast in one of private Indonesian TVs, is categorized into child’s program since it is broadcast at child’s prime time, Sunday 08.30 a.m. In spite of its broadcast time, this series consist of symbols directed not for children, such as some acts that are not appropriate to be done by children, especially in Indonesia. Moreover, adult symbols of sex are also found in the program. For this reason it will be interesting to analyze it using semiotic analysis. Semiotics is the study of symbol and its meaning which its principle concept is that both signifier and signified consist of symbols and are related to denotation and connotation.   Crayon Shin Chan merupakan serial animasi dua dimensi yang tayang di salah satu stasiun televisi swasta di Indonesia. Ini merupakan produk animasi 2 dimensi yang diimpor dari Jepang. Di Indonesia, serial ini masuk dalam kategori acara anak. Hal ini dapat dilihat dari jam penayangannya yang merupakan waktu prime time bagi anak, yakni pada hari minggu pukul 08.30. Akan tetapi, pada serial ini banyak simbol-simbol yang mengarah pada tayangan yang bukan untuk anak-anak, yakni adeganadegan yang tidak pantas dilakukan oleh anak khususnya di Indonesia. Serta adanya pula simbol-simbol yang mengarah pada tayangan berbau dewasa. Tentu akan menarik jika tayangan ini diteliti menggunakan analisis semiotika. Semiotika sendiri merupakan kajian ilmu mengenai tanda dan makna. Yang pada prinsipnya, konsep penting seperti penanda (signifier dan petanda (signified sama-sama terdiri dari tanda dan terkait dengan denotasi dan konotasi.

  10. The Productivity Advantage of Serial Entrepreneurs

    DEFF Research Database (Denmark)

    Shaw, Kathryn L.; Sørensen, Anders

    Serial entrepreneurs, who open more than one business, are found to have higher sales and higher productivity than novice entrepreneurs, who open one business. Using panel data on entrepreneurs and their firms from Denmark for 2001-2013, the serial entrepreneur has 67% higher sales than the novice......, but also opens firms that are larger in terms of the initial capital and labor, and thus is 39% more productive. There are subsets of firms that perform especially well – serial entrepreneurs that hold a portfolio of overlapping ongoing firms perform the best, as do those that open as limited liability...

  11. The American Serialization of Lord Jim

    Directory of Open Access Journals (Sweden)

    Stephen Donovan

    2017-12-01

    Full Text Available This essay presents the discovery of the American serialization of Joseph Conrad’s Lord Jim in New York’s Evening Telegram in 1903. This ‘lost’ serialization, it argues, invites a new perspective on Conrad’s early career by foregrounding the role of newspaper serialization and syndication in establishing his literary standing. After surveying the principal differences in the respective reading experiences of the periodical versus the book, it concludes by proposing that the prominence of women among Conrad’s first audiences requires us to reassess the basis for his success in North America and elsewhere.

  12. Religious beliefs and alcohol control policies: a Brazilian nationwide study

    Directory of Open Access Journals (Sweden)

    Giancarlo Lucchetti

    2014-03-01

    Full Text Available Objective: The connection between lower alcohol use and religiousness has been extensively examined. Nevertheless, few studies have assessed how religion and religiousness influence public policies. The present study seeks to understand the influence of religious beliefs on attitudes toward alcohol use. Methods: A door-to-door, nationwide, multistage population-based survey was carried out. Self-reported religiousness, religious attendance, and attitudes toward use of alcohol policies (such as approval of public health interventions, attitudes about drinking and driving, and attitudes toward other alcohol problems and their harmful effects were examined. Multiple logistic regression was used to control for confounders and to assess explanatory variables. Results: The sample was composed of 3,007 participants; 57.3% were female and mean age was 35.7 years. Religiousness was generally associated with more negative attitudes toward alcohol, such as limiting hours of sale (p < 0.01, not having alcohol available in corner shops (p < 0.01, prohibiting alcohol advertisements on TV (p < 0.01, raising the legal drinking age (p < 0.01, and raising taxes on alcohol (p < 0.05. Higher religious attendance was associated with less alcohol problems (OR: 0.61, 95%CI 0.40-0.91, p = 0.017, and self-reported religiousness was associated with less harmful effects of drinking (OR: 0.61, 95%CI 0.43-0.88, p = 0.009. Conclusions: Those with high levels of religiousness support more restrictive alcohol policies. These findings corroborate previous studies showing that religious people consume less alcohol and have fewer alcohol-related problems.

  13. Rethinking Study and Management of Agricultural Systems for Policy Design

    Directory of Open Access Journals (Sweden)

    Johann Baumgärtner

    2013-09-01

    Full Text Available There is a concern that agriculture will no longer be able to meet, on a global scale, the growing demand for food. Facing such a challenge requires new patterns of thinking in the context of complexity and sustainability sciences. This paper, focused on the social dimension of the study and management of agricultural systems, suggests that rethinking the study of agricultural systems entails analyzing them as complex socio-ecological systems, as well as considering the differing thinking patterns of diverse stakeholders. The intersubjective nature of knowledge, as studied by different philosophical schools, needs to be better integrated into the study and management of agricultural systems than it is done so far, forcing us to accept that there are no simplistic solutions, and to seek a better understanding of the social dimension of agriculture. Different agriculture related problems require different policy and institutional approaches. Finally, the intersubjective nature of knowledge asks for the visualization of different framings and the power relations taking place in the decision-making process. Rethinking management of agricultural systems implies that policy making should be shaped by different principles: learning, flexibility, adaptation, scale-matching, participation, diversity enhancement and precaution hold the promise to significantly improve current standard management procedures.

  14. Energy Policy Case Study - Texas: Wind, Markets, and Grid Modernization

    Energy Technology Data Exchange (ETDEWEB)

    Orrell, Alice C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Homer, Juliet S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Bender, Sadie R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Weimar, Mark R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-09-19

    This document presents a case study of energy policies in Texas related to power system transformation, renewable energy and distributed energy resources (DERs). Texas has experienced a dramatic increase in installed wind capacity, from 116 MW in 2000 to over 15,000 MW in 2015. This achievement was enabled by the designation of Competitive Renewable Energy Zones (CREZs) and new transmission lines that transmit wind to load centers. This report highlights nascent efforts to include DERs in the ERCOT market. As costs decline and adoption rates increase, ERCOT expects distributed generation to have an increasing effect on grid operations, while bringing potentially valuable new resources to the wholesale markets.

  15. Process, paper policy and practice : a case study of the introduction of a formal extension policy in Queensland, Australia 1987 - 1994

    NARCIS (Netherlands)

    Coutts, J.A.

    1994-01-01

    This study explores the policy element of public sector agricultural extension. It was contended that this policy element lacked an adequate framework. Without such a framework, there was a risk that major policy - or operational - issues would be neglected in policy formulation. The study

  16. Moving Forward with School Nutrition Policies: A Case Study of Policy Adherence in Nova Scotia.

    Science.gov (United States)

    McIsaac, Jessie-Lee D; Shearer, Cindy L; Veugelers, Paul J; Kirk, Sara F L

    2015-12-01

    Many Canadian school jurisdictions have developed nutrition policies to promote health and improve the nutritional status of children, but research is needed to clarify adherence, guide practice-related decisions, and move policy action forward. The purpose of this research was to evaluate policy adherence with a review of online lunch menus of elementary schools in Nova Scotia (NS) while also providing transferable evidence for other jurisdictions. School menus in NS were scanned and a list of commonly offered items were categorized, according to minimum, moderate, or maximum nutrition categories in the NS policy. The results of the menu review showed variability in policy adherence that depended on food preparation practices by schools. Although further research is needed to clarify preparation practices, the previously reported challenges of healthy food preparations (e.g., cost, social norms) suggest that many schools in NS are likely not able to use these healthy preparations, signifying potential noncompliance to the policy. Leadership and partnerships are needed among researchers, policy makers, and nutrition practitioners to address the complexity of issues related to food marketing and social norms that influence school food environments to inspire a culture where healthy and nutritious food is available and accessible to children.

  17. Interorganizational Policy Studies: Lessons Drawn from Implementation Research

    NARCIS (Netherlands)

    O'Toole, Laurence J.

    1993-01-01

    Contingency approaches to organizing suggest that policy objectives are more likely to be achieved if the structures employed for implementation mesh with the policy objectives being sought. Interorganizational arrangements are used increasingly in carrying out public programs, and contingency logic

  18. Ministry of health on facebook: an information policy case study

    Directory of Open Access Journals (Sweden)

    Flávia Moraes Moreira

    2015-09-01

    Full Text Available Introduction: The growth of social networks on the internet is visible. Everywhere people use these tools on various places, either via desktop, laptop, tablet or smartphone. In Brazil, the most prominent network in recent years is Facebook, which reached 76 million users in June 2013, an unprecedented number in the country. The growth allowed governments to perceive this virtual space as a potential place to present their work and communicate with society. Objectives: The study goal is to observe how information has been publicized by the Ministry of Health through Facebook since 2010 (year of creation of the page until October 2013, taking as an analytical category the implemented information policy, in order to propose a discussion about democratization of access to health information. Methodology: case study; Non-participant observation, data collection and documental analysis. Results: The main issues addressed by the Ministry of Health on Facebook are organizational actions and government programs instead of posts with guidance for a healthy living style. Also noteworthy is the low interaction of the Ministry page moderators with the users profile. The study showed most of the questions and comments made by the public are not answered by the institutional body. Conclusions: Need of strengthening the mediaton process of the information policies from the Ministry of Health on Facebook.

  19. A Case Study of Gender Neutral Policies in University Housing

    Science.gov (United States)

    Chave, Josh

    2014-01-01

    Gender neutral housing is an innovative new policy being developed in colleges around the country. One reason to create these policies is an attempt to meet the unique needs and challenges of lesbian, gay, bisexual, and transgender students. As the number of gender neutral housing policies in the United States continues to rise, research has been…

  20. Some Considerations on Seriality and Synchronicity

    OpenAIRE

    Elena Nechita

    2010-01-01

    This paper presents an overview of the results that have been obtained lately on seriality and synchronicity and their link, in the light of the new theories and within the frame of complexity science.

  1. Some Considerations on Seriality and Synchronicity

    Directory of Open Access Journals (Sweden)

    Elena Nechita

    2010-01-01

    Full Text Available This paper presents an overview of the results that have been obtained lately on seriality and synchronicity and their link, in the light of the new theories and within the frame of complexity science.

  2. Active Aging Policies between Individual Needs and Collective Goods. A Study of Active Aging Policies and Practices in Norway

    Directory of Open Access Journals (Sweden)

    Tove Midtsundstad

    2014-05-01

    Full Text Available A main objective of European governments is to reduce the number of early retirees, either by reforming pension systems or promoting active aging in working life. The importance of formulating a coherent personnel policy for all age groups is increasingly recognized by employers. However, there is still a lack of knowledge as how to strategically cope with an aging labor force. The aim of this article is to define and discuss a number of challenges arising from workplace-related active aging policies. We in particular discuss how an emphasis on economic incentives and gains (“senior goods” may give rise to unanticipated side effects for the employers as well as the employees. The article is based on results from two recent studies: one study examining six Norwegian municipalities with seemingly good practices in work-related old age policies, and another examining such policies in eight establishments in four different industries.

  3. Linking biomedical engineering ethics case study approach and policy.

    Science.gov (United States)

    Dibrell, William; Dobie, Elizabeth Ann

    2007-01-01

    In this paper we link bioengineering case study methods to the development of policy. The case study approach to ethics is an excellent way to show the complex nature of practical/moral reasoning. This approach can, however, lead to a kind of overwhelming complexity. The individual nature of each case makes it difficult to identify the most important information and difficult to see what moral considerations are most relevant. In order to make the overwhelming complexity less debilitating, we present a framework for moral decision making derived from suggestions made by W.D. Ross and Virginia Held. Ross articulates the multiple sources of morality and Held deepens the discussion by reminding us of the foundational importance of care and sympathy to our moral natures. We show how to use the notion of prima facie duty and discuss moral conflict. In doing this, we show how the framework, applied to cases, can be of assistance in helping us develop policies and codes of ethics with sufficient plasticity to be useful in the complex world of the bioengineer.

  4. Research Design in the study of the European Neighbourhood Policy

    DEFF Research Database (Denmark)

    Exadaktylos, Theofanis; Lynggaard, Kennet

    2017-01-01

    This chapter deals with the pitfalls and pathways of research design aimed at the study of the European Neighbourhood Policy (ENP) and maps out the literature on questions of knowledge ambition, research ontology and epistemology, and choices of approaches to the research object. We include...... a review of traditional research designs in ENP research, through a systematic meta-analysis of a selection of the most-cited articles on the ENP. Inspired by earlier work on awareness of research design in EU studies, ENP research is categorised according to typical choices of research design in the form...... of dichotomous trade-offs. The chapter then discusses how individual contributions to this volume deal with research design challenges of the past and present innovative ways of studying the revised ENP....

  5. Policy study: energy conservation in transportation in Puerto Rico

    Energy Technology Data Exchange (ETDEWEB)

    Mayda, J

    1978-09-01

    The present study is an initial effort to apply social system analysis to transportation energy conservation, in order to prepare the ground for a team effort of transportation and energy specialists, regional planners, policy analysis and generalists, and government administrators - with additional imputs from commerce, industry and the community at large. The task of this study has been to inventory the principal factors and inputs in the field of transportation energy demand and possible conservation, estimate their magnitudes and relations, and arrange in a tentative but reasoned pattern - where there were before only so many scattered data, technical studies with a limited focus, sectoral programs and decisions, and vague impressions about the serviceability, the impacts and the social value of the product.

  6. Development of FPGA-based High Speed Serial Links for High Energy Physics Experiments

    CERN Document Server

    Perrella, Sabrina; Giordano, Raffaele; Izzo, Vincenzo

    Ricerca Simple Search Advanced Search Ultime accessioni Browse Browse by Author Browse by Subject Browse by Year Browse by Type Browse by Accessibilità del full-text Informazioni Policy About FAQ Contatti Perrella, Sabrina (2016) Development of FPGA-based High-Speed serial links for High Energy Physics Experiments. [Tesi di dottorato] [img] Text Perrella_Sabrina_28.pdf Download (59MB) | Preview [error in script] [error in script] Item Type: Tesi di dottorato Lingua: English Title: Development of FPGA-based High-Speed serial links for High Energy Physics Experiments Creators: Creators\tEmail Perrella, Sabrina\tsa.perrella@gmail.com Date: 31 March 2016 Number of Pages: 113 Institution: Università degli Studi di Napoli Federico II Department: Fisica Scuola di dottorato: Scienze fisiche Dottorato: Fisica fondamentale ed applicata Ciclo di dottorato: 28 Coordinatore del Corso di dottorato: nome\temail Velotta, Raffaele\tvelotta@na.infn.it Tutor: nome\temail Alviggi, Mariagrazia\tUNSPECIFIED Giordano, ...

  7. The effects of nidopallium caudolaterale inactivation on serial-order behaviour in pigeons (Columba livia).

    Science.gov (United States)

    Johnston, Melissa Jane; Clarkson, Andrew N; Gowing, Emma K; Scarf, Damian; Colombo, Mike

    2018-06-06

    Serial-order behaviour is the ability to complete a sequence of responses in a predetermined order to achieve a reward. In birds, serial-order behaviour is thought to be impaired by damage to the nidopallium caudolaterale (NCL). In the current study, we examined the role of the NCL in serial-order behaviour by training pigeons on a 4-item serial-order task and a go/no-go discrimination task. Following training, pigeons were received infusions of 1μl of either tetrodotoxin (TTX) or saline. Saline infusions had no impact on serial-order behaviour whereas TTX infusions resulted in a significant decrease in performance. The serial-order impairments, however, were not the results of errors of any specific error at any specific list item. With respect to the go/no-go discrimination task, saline infusions also had no impact on performance whereas TTX infusions impaired pigeons' discrimination abilities. Given the impairments on the go/no-go discrimination task, which does not require processing of serial-order information, we tentatively conclude that damage to the NCL does not impair serial-order behaviour per se, but rather results in a more generalised impairment that may impact performance across a range of tasks.

  8. Kinematics and dynamics analysis of a novel serial-parallel dynamic simulator

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Bo; Zhang, Lian Dong; Yu, Jingjing [Parallel Robot and Mechatronic System Laboratory of Hebei Province, Yanshan University, Qinhuangdao, Hebei (China)

    2016-11-15

    A serial-parallel dynamics simulator based on serial-parallel manipulator is proposed. According to the dynamics simulator motion requirement, the proposed serial-parallel dynamics simulator formed by 3-RRS (active revolute joint-revolute joint-spherical joint) and 3-SPR (Spherical joint-active prismatic joint-revolute joint) PMs adopts the outer and inner layout. By integrating the kinematics, constraint and coupling information of the 3-RRS and 3-SPR PMs into the serial-parallel manipulator, the inverse Jacobian matrix, velocity, and acceleration of the serial-parallel dynamics simulator are studied. Based on the principle of virtual work and the kinematics model, the inverse dynamic model is established. Finally, the workspace of the (3-RRS)+(3-SPR) dynamics simulator is constructed.

  9. Kinematics and dynamics analysis of a novel serial-parallel dynamic simulator

    International Nuclear Information System (INIS)

    Hu, Bo; Zhang, Lian Dong; Yu, Jingjing

    2016-01-01

    A serial-parallel dynamics simulator based on serial-parallel manipulator is proposed. According to the dynamics simulator motion requirement, the proposed serial-parallel dynamics simulator formed by 3-RRS (active revolute joint-revolute joint-spherical joint) and 3-SPR (Spherical joint-active prismatic joint-revolute joint) PMs adopts the outer and inner layout. By integrating the kinematics, constraint and coupling information of the 3-RRS and 3-SPR PMs into the serial-parallel manipulator, the inverse Jacobian matrix, velocity, and acceleration of the serial-parallel dynamics simulator are studied. Based on the principle of virtual work and the kinematics model, the inverse dynamic model is established. Finally, the workspace of the (3-RRS)+(3-SPR) dynamics simulator is constructed

  10. STUDY ON COMPANY SECURITY POLICIES FROM DIGITAL MEDIA

    Directory of Open Access Journals (Sweden)

    CRISTINA-MARIA RĂDULESCU

    2015-12-01

    Full Text Available The Internet development has brought both new opportunities and risks for either retailers or consumers. For example, electronic commerce is much faster and less expensive, but this openness makes it difficult to secure. People are aware of the fact that online businesses collecting, process and distribute enormous amounts of personal data and therefore, are concerned about their unauthorized use or their use in other purposes than intended by third parties in order to gain unauthorized access to them. There are more examples of cyber criminal activities, such as: hacking, software piracy, passwords attack, service prohibition attacks, scamming, etc. Such fears led to the editing of protection policies meant to secure personal data and to develop some mechanisms to ensure the reliability and confidentiality of electronic information. Security measures include access control devices, installation of firewalls and intrusion detection devices, of some security procedures to identify and authenticate authorized users of network systems. Such mechanisms constitute the core of this study. We will also analyze security and confidentiality policy of personal data of Google Inc.

  11. A study on the denuclearization policy in Korean peninsular

    International Nuclear Information System (INIS)

    Song, I. J.; Park, D. K.; Choi, Y. S.

    2001-01-01

    The prime ministers of North Korea and South Korea adopted 'Joint Declaration of the Denuclearization of the Korean Peninsular' (Joint Declaration) on December 31, 1991. Unprecedented as an agreement between two political powers of a divided country, this Joint Declaration is important for its historical significance. To analyze the denuclearization policy in the Korean peninsular, this dissertation suggests a framework which can be established on the factors facilitating the denuclearization both on the level of international politics and on the politics of a divided country. A substantial nuclear proliferation theory should be based on the study in detail of the nuclear proliferation cases of about 40 individual countries. This dissertation may be meaningful as a concrete study of the denuclearzation in the Korean peninsular on theoretical and practical basis

  12. Study on management policy of Biocides in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jeong Kyu; Cho, Young Hee [Korea Environment Institute, Seoul (Korea)

    1999-12-01

    In the advanced countries, there are active studies on biocide, implying non-agricultural pesticides, at present with increasing interests on this. Among the advanced countries, Canada, Australia and New Zealand are managing biocides the most systematically and have very clear regulations and roles of relevant departments. In addition to efforts of each country, the international organizations are emphasizing the need of biocides management. EU already announced Biocidal Products Directive(BPD) in 1998 and is urging to implement regulations within a guidebook in member countries from 2000. Furthermore, OECD is well aware of biocides management trend of each member country and is planning to set up a specific management guide based on this. In this study, it recommends a biocides management policy in Korea with regulations, relevant departments, and regulation contents of biocides implemented in the advanced countries and regulation trend of biocides in Korea. 47 refs., 27 tabs.

  13. Using Serial and Discrete Digit Naming to Unravel Word Reading Processes.

    Science.gov (United States)

    Altani, Angeliki; Protopapas, Athanassios; Georgiou, George K

    2018-01-01

    During reading acquisition, word recognition is assumed to undergo a developmental shift from slow serial/sublexical processing of letter strings to fast parallel processing of whole word forms. This shift has been proposed to be detected by examining the size of the relationship between serial- and discrete-trial versions of word reading and rapid naming tasks. Specifically, a strong association between serial naming of symbols and single word reading suggests that words are processed serially, whereas a strong association between discrete naming of symbols and single word reading suggests that words are processed in parallel as wholes. In this study, 429 Grade 1, 3, and 5 English-speaking Canadian children were tested on serial and discrete digit naming and word reading. Across grades, single word reading was more strongly associated with discrete naming than with serial naming of digits, indicating that short high-frequency words are processed as whole units early in the development of reading ability in English. In contrast, serial naming was not a unique predictor of single word reading across grades, suggesting that within-word sequential processing was not required for the successful recognition for this set of words. Factor mixture analysis revealed that our participants could be clustered into two classes, namely beginning and more advanced readers. Serial naming uniquely predicted single word reading only among the first class of readers, indicating that novice readers rely on a serial strategy to decode words. Yet, a considerable proportion of Grade 1 students were assigned to the second class, evidently being able to process short high-frequency words as unitized symbols. We consider these findings together with those from previous studies to challenge the hypothesis of a binary distinction between serial/sublexical and parallel/lexical processing in word reading. We argue instead that sequential processing in word reading operates on a continuum

  14. The Study on Policy Options for Siting Hazardous Energy Facility

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jin Oh [Korea Energy Economics Institute, Euiwang (Korea)

    2000-10-01

    The problem of site allocation on locally unwanted land uses related to energy utilities that extended most recently is becoming a new energy policy issue due to the improvement of national standard of living and livelihood quality. Residents do not generally agree on establishing the construction of public energy utilities in their village due to NIMBY syndrome while they basically agree to have them. These circumstances made a big problem against mass production of industry society and the improvement of the national welfare. Locally unwanted land use related to energy utilities includes waste incineration system, nuclear power plant, coal fired power plant, oil and Gas storage tank, briquette manufacturing plant and etc. Opportunity for SOC projects carried out by central and local government is lost because of the regional egoism. The site dispute between government and residents obstructs optimal energy supply to be necessary for industry growth and the national welfare. The main objective of this study is to propose the policy option for finding a solution after surveying theory and background of site troubles and dispute factors. Final results of this study propose a solution on structural and institutional dispute. The former introduces three kinds of approaches such as tradition, compensation and negotiation. The transition of an environmentally sound energy consumption pattern and the improvement of energy efficiency could be carried out by traditional approaches. To claim the damage and offer the accommodation facilities could be settled by compensational approaches. The establishment of regional decentralization on NIMBY facilities could be settled by negotiatory approaches through fair share criteria. The latter proposes 1) 'polluter pays principle', 2) internalization of social cost and benefit on air or water pollution, 3) the behind - the - scene negotiation in a bid to settle a site dispute, 4) and supporting system for peripheral areas

  15. A Local Dimension of Integration Policies? A Comparative Study of Berlin, Malmö, and Rotterdam

    NARCIS (Netherlands)

    R. Dekker (Rianne); H. Emilsson (Henrik); B. Krieger (Bernhard); P.W.A. Scholten (Peter)

    2015-01-01

    textabstractThis study examines three theses on local integration policies by a qualitative comparative case study of integration policies in three cities in three different countries (Berlin, Malmö, and Rotterdam). We found little evidence of a congruent local dimension of integration policies.

  16. Government Accountability Reports and Public Education Policy: Studying Political Actors' Decision-Making

    Science.gov (United States)

    Salazar, Timothy Ross

    2013-01-01

    This study asks how government accountability reports are used to influence public education policy. Government accountability reports, called "audits" in Utah, prove to be useful tools for examining education policy. Using a collective case study design examining Utah's Class Size Reduction (CSR) policy, government accountability…

  17. A study on the alternative option for nuclear policy

    Energy Technology Data Exchange (ETDEWEB)

    Choi, J. W.; Choi, H. J.; Lee, J. Y.; Cho, D. K.; Jeon, K. S.; Park, S. W.; Hahn, D. H.; Yoon, J. S.; Lee, K. S. [KAERI, Daejeon (Korea, Republic of)

    2008-02-15

    Since a decision-making by intuitive judgement under uncertain future conditions can not select an optimum alternative, reaching an agreement for alternatives between experts requires a development of several scientific opinion collection methodologies and performing these methodologies. Therefore, opinion collection for all points related to the nuclear energy, public hearing induction related researches and the acts, procedure, etc. performed in developed countries such as U.S, U.K, France, etc. are reviewed and analyzed in this research. And after the analysis of domestic spent nuclear fuel management plan, Task Force Team composed of experts in several related areas is organized to suggest strategies and directions which are necessary for making a national policy. Beside, Task Force Team selects an optimum technical alternative by the analysis and comparison in depth between these technical alternatives to establish the policy direction. They also established the procedures such as opinion collecting, etc. through policy conference and forum and suggested the technical data related nuclear policy which supports the nuclear policy conference. Results from this research are expected to decrease the trial and error that has been occurred in the present policy-making procedure such as radioactive waste repository related procedure and contribute for socio-cultural stability. Moreover, opinion collection plan for developing a nuclear policy alternative is expected to contribute for making a nuclear policy in the nuclear policy conference so that the nuclear technology will be enhanced more.

  18. A study on the alternative option for nuclear policy

    International Nuclear Information System (INIS)

    Choi, J. W.; Choi, H. J.; Lee, J. Y.; Cho, D. K.; Jeon, K. S.; Park, S. W.; Hahn, D. H.; Yoon, J. S.; Lee, K. S.

    2008-02-01

    Since a decision-making by intuitive judgement under uncertain future conditions can not select an optimum alternative, reaching an agreement for alternatives between experts requires a development of several scientific opinion collection methodologies and performing these methodologies. Therefore, opinion collection for all points related to the nuclear energy, public hearing induction related researches and the acts, procedure, etc. performed in developed countries such as U.S, U.K, France, etc. are reviewed and analyzed in this research. And after the analysis of domestic spent nuclear fuel management plan, Task Force Team composed of experts in several related areas is organized to suggest strategies and directions which are necessary for making a national policy. Beside, Task Force Team selects an optimum technical alternative by the analysis and comparison in depth between these technical alternatives to establish the policy direction. They also established the procedures such as opinion collecting, etc. through policy conference and forum and suggested the technical data related nuclear policy which supports the nuclear policy conference. Results from this research are expected to decrease the trial and error that has been occurred in the present policy-making procedure such as radioactive waste repository related procedure and contribute for socio-cultural stability. Moreover, opinion collection plan for developing a nuclear policy alternative is expected to contribute for making a nuclear policy in the nuclear policy conference so that the nuclear technology will be enhanced more

  19. An economic evaluation of salt reduction policies to reduce coronary heart disease in England: a policy modeling study.

    Science.gov (United States)

    Collins, Marissa; Mason, Helen; O'Flaherty, Martin; Guzman-Castillo, Maria; Critchley, Julia; Capewell, Simon

    2014-07-01

    Dietary salt intake has been causally linked to high blood pressure and increased risk of cardiovascular events. Cardiovascular disease causes approximately 35% of total UK deaths, at an estimated annual cost of £30 billion. The World Health Organization and the National Institute for Health and Care Excellence have recommended a reduction in the intake of salt in people's diets. This study evaluated the cost-effectiveness of four population health policies to reduce dietary salt intake on an English population to prevent coronary heart disease (CHD). The validated IMPACT CHD model was used to quantify and compare four policies: 1) Change4Life health promotion campaign, 2) front-of-pack traffic light labeling to display salt content, 3) Food Standards Agency working with the food industry to reduce salt (voluntary), and 4) mandatory reformulation to reduce salt in processed foods. The effectiveness of these policies in reducing salt intake, and hence blood pressure, was determined by systematic literature review. The model calculated the reduction in mortality associated with each policy, quantified as life-years gained over 10 years. Policy costs were calculated using evidence from published sources. Health care costs for specific CHD patient groups were estimated. Costs were compared against a "do nothing" baseline. All policies resulted in a life-year gain over the baseline. Change4life and labeling each gained approximately 1960 life-years, voluntary reformulation 14,560 life-years, and mandatory reformulation 19,320 life-years. Each policy appeared cost saving, with mandatory reformulation offering the largest cost saving, more than £660 million. All policies to reduce dietary salt intake could gain life-years and reduce health care expenditure on coronary heart disease. Copyright © 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  20. Innovation Policies: A comparative study Between Brazil and France

    Directory of Open Access Journals (Sweden)

    Graciela Dias Coelho Jones

    2017-03-01

    Full Text Available The aim of this study is to present a comparison between the main actions promoted to encourage innovation by France, as well as the current stage of research and development initiatives (R&D, in relation to Brazil. Is a qualitative study that the procedures for its development ranks as literature and documents. The data collection technique was documentary and had as a data source primary and secondary documents, coming from public archives and statistical sources. For the survey of brazilian data for the development of this study, it was used as informational basis the fifth edition of the Innovation Research (PINTEC 2011. The data from France raised through the use of OECD year Report 2014 " Reviews of Innovation Policy France in 2014."  For the presentation of the study results comparative charts and tables were used. As the present study results can be highlighted, among others: France is a country with a long scientific tradition and technique, and plays a significant role in the world in this area. On the other hand, Brazil has one of the lowest proportions of R&D and export of high technology to GDP. The completion of this study brought an important diagnosis: there is a wide and interesting research topic that is still little explored by Brazilian researchers.

  1. Does ICT Policy Improve Interorganisational ICT for SMEs? A Dutch Policy Evaluation Study

    NARCIS (Netherlands)

    Plomp, M.G.A.; Batenburg, R.S.; Den Hertog, P.

    2011-01-01

    Interorganisational ICT has become critical for the performance of both small and large organisations. SMEs however, traditionally lag behind in the uptake of these systems. In many countries, various policy programmes are initiated to improve ICT uptake by SMEs and support them in digital linking

  2. Does ICT policy improve interorganisational ICT for SMEs? A Dutch policy evaluation study.

    NARCIS (Netherlands)

    Plomp, M.G.A.; Batenburg, R.S.; Hertog, P. den

    2011-01-01

    Interorganisational ICT has become critical for the performance of both small and large organisations. SMEs however, traditionally lag behind in the uptake of these systems. In many countries, various policy programmes are initiated to improve ICT uptake by SMEs and support them in digital linking

  3. Study on Formulating Policy and Strategies for IAEA TC Program

    International Nuclear Information System (INIS)

    Min, B. J.; Lee, M. K.; Shin, J. Y.

    2010-10-01

    The objectives of this study is to provide recommendations for formulating adequate policy and strategies for IAEA-TC programme as being of a donor Member State and to guide directions to facing the challenges of changing the status from IAEA-TC recipient to donor country. In addition, this study gives recommendations and feedbacks to the IAEA-TC programmer: how it has contributed to nation's nuclear technology development in the past on one hand and how the country has contributed to it on the other. Besides, this study also conducted to identify the following impacts expected: termination of on-going National TC projects, discontinuation of TC-based technical advices, sponsored fellowship and scientific visits for capacity building opportunities, and limitation in participations of various regional projects due to termination of IAEA financial support. In terms of financial aspect, this study has also performed to assess the nation's annual financial contribution (Technical Cooperation (TC) Fund: 1,67 million dollars in 2008) by comparing the experiences of other OECD countries cases. In conclusion, it is expected that the results of this study will contribute to develop appropriate measures in order to maximize the benefits for future national nuclear technology development and in addition, to explore the possibilities to extend the nuclear technology export market potentials

  4. Broad ion beam serial section tomography

    Energy Technology Data Exchange (ETDEWEB)

    Winiarski, B., E-mail: b.winiarski@manchester.ac.uk [School of Materials, University of Manchester, Manchester M13 9PL (United Kingdom); Materials Division, National Physical Laboratory, Teddington TW11 0LW (United Kingdom); Gholinia, A. [School of Materials, University of Manchester, Manchester M13 9PL (United Kingdom); Mingard, K.; Gee, M. [Materials Division, National Physical Laboratory, Teddington TW11 0LW (United Kingdom); Thompson, G.E.; Withers, P.J. [School of Materials, University of Manchester, Manchester M13 9PL (United Kingdom)

    2017-01-15

    Here we examine the potential of serial Broad Ion Beam (BIB) Ar{sup +} ion polishing as an advanced serial section tomography (SST) technique for destructive 3D material characterisation for collecting data from volumes with lateral dimensions significantly greater than 100 µm and potentially over millimetre sized areas. Further, the associated low level of damage introduced makes BIB milling very well suited to 3D EBSD acquisition with very high indexing rates. Block face serial sectioning data registration schemes usually assume that the data comprises a series of parallel, planar slices. We quantify the variations in slice thickness and parallelity which can arise when using BIB systems comparing Gatan PECS and Ilion BIB systems for large volume serial sectioning and 3D-EBSD data acquisition. As a test case we obtain 3D morphologies and grain orientations for both phases of a WC-11%wt. Co hardmetal. In our case we have carried out the data acquisition through the manual transfer of the sample between SEM and BIB which is a very slow process (1–2 slice per day), however forthcoming automated procedures will markedly speed up the process. We show that irrespective of the sectioning method raw large area 2D-EBSD maps are affected by distortions and artefacts which affect 3D-EBSD such that quantitative analyses and visualisation can give misleading and erroneous results. Addressing and correcting these issues will offer real benefits when large area (millimetre sized) automated serial section BIBS is developed. - Highlights: • In this work we examine how microstructures can be reconstructed in three-dimensions (3D) by serial argon broad ion beam (BIB) milling, enabling much larger volumes (>250×250×100µm{sup 3}) to be acquired than by serial section focused ion beam-scanning electron microscopy (FIB-SEM). • The associated low level of damage introduced makes BIB milling very well suited to 3D-EBSD acquisition with very high indexing rates. • We explore

  5. Art and technology: A comparative study of policy legitimation

    NARCIS (Netherlands)

    N.M. Wijnberg (Nachoem)

    1994-01-01

    textabstractThe legitimation of technology policy is discussed from the point of view of the neoclassical and of the dynamic, Schumpeterian, approach. The results are presented, using the traditional categories of policy legitimation in welfare theory: public goods, externalities, and merit goods.

  6. Evaluation of energy efficiency policy instruments effectiveness : case study Croatia

    International Nuclear Information System (INIS)

    Bukarica, V.

    2007-01-01

    This paper proposed a theoretical basis for evaluating energy efficiency policy in the Republic of Croatia and corroborated it with the analysis of energy efficiency market development and transformation. The current status of the market was evaluated and policy instruments were adapted to achieve optimal results. In particular, the energy efficiency market in Croatia was discussed in terms of micro and macro environment factors that influence policy making processes and the choice of policy instruments. The macro environment for energy efficiency market in Croatia is the process of European Union pre-integration with all related national and international legislation, political and economical factors and potential to use financial funds. The micro environment consists of government institutions, local financing institutions and a range of market players on the supply and demand side. Energy efficiency is the most powerful and cost-effective way for achieving goals of sustainable development. Policy instruments developed to improve energy efficiency are oriented towards a cleaner environment, better standard of living, more competitive industry and improved security of energy supply. Energy efficiency is much harder to implement and requires policy interventions. In response to recent trends in the energy sector, such as deregulation and open competition, policy measures aimed at improving energy efficiency should shift from an end-users oriented approach towards a whole market approach. The optimal policy instruments mix should be designed to meet defined targets. However, market dynamics must be taken into consideration. 9 refs., 4 figs

  7. Municipal climate change policies. A case study for Amsterdam

    International Nuclear Information System (INIS)

    Schol, E.; Van den Bosch, A.; Ligthart, F.A.T.M.; Roemer, J.C.; Ruijg, G.J.; Schaeffer, G.J.; Dinkelman, G.H.; Kok, I.C.; De Paauw, K.F.B.

    1999-01-01

    Insight in the local policy options with respect to climate change is provided, in this case within the sphere of influence of Amsterdam local authorities. A list of new policy options for CO 2 reduction has been made with the assistance of local policy makers and representatives of interest groups. These policy options have been divided into three qualitative scenarios: Institutional Cultural Change, Technological Innovation and Least-Regrets. The environmental, economic and other effects have been described for each policy option. The three most interesting policy options have been selected by local policymakers and representatives of interest groups during a workshop. Implementation strategies have been developed for the options selected. These strategies have been discussed during a second workshop. The reduction target, stabilisation of CO 2 emissions in 2015 compared to 1993, can be reached by a combination of all the new policy options. The three selected policy options count for 40% of this total CO 2 emission reduction. Finally, a general outline on the methodology can also be applied to other cities and municipalities. For example, this methodology can be used by participants of Cities for Climate Protection, an initiative of the International Council for Local Environmental Initiatives, or the Netherlands Climate Association. 136 refs

  8. Toward a Theoretical Framework for Studying Climate Change Policies: Insights from the Case Study of Singapore

    Directory of Open Access Journals (Sweden)

    Ai Sian Ng

    2017-07-01

    Full Text Available The world decided in December 2015 to take actions to reduce global warming. To contribute toward this goal, this research examines possible policy levers for inclusion in the climate change ratification plan. A case study of the measures taken by the Republic of Singapore, a low-lying 719.2 km2 island without natural resources in Asia, is conducted. Being vulnerable to climate change impact and yet having to balance her people’s needs and economic progress with limited resources, the measures taken by this small country could offer policy insights for small states and states without access to alternative energy sources. This research analyzes the online policy documents posted by eleven organizations to answer the main research question of identifying policy levers as theoretical constructs to form a framework that can be used to study climate change policies. A qualitative data analysis software, QSR NVivo 10, is used to classify the proposed nodes developed by the researchers using a system perspective integrating the insights from the key international climate change frameworks with the theoretical concepts from the model of pro-environmental behavior. The findings can offer insights toward developing a new contextual influence framework, which can help strengthen policy development and outcome measurement.

  9. Engaging Actors for Integrating Health Policy and Systems Research into Policy Making: Case Study from Haryana State in India

    Directory of Open Access Journals (Sweden)

    Shankar Prinja

    2017-09-01

    Full Text Available Background & objective: Good examples of evidence generation using Health Policy and Systems Research (HPSR in low and middle income countries (LMIC; and its application in policy making are scarce. In this paper, we describe the experience of establishing a system of HPSR from the Haryana state in India, outline how the HPSR is being utilized for policy making and programmatic decision making, and analyse the key factors which have been critical to the implementation and uptake of HPSR. Methods: Multiple methods are employed in this case study, ranging from unstructured in-depth interviews, review of the program and policy documents, and participatory notes from the meetings. The steps towards creation of a knowledge partnership between stakeholders are outlined. Four case studies i.e. development of a plan for universal health care (UHC, nutrition policy, centralized drug procurement system and use of RAPID appraisal method highlight the use of research evidence in agenda setting, policy formulation and policy implementation respectively. Results: Our analysis shows that the most important factor which contributed to Haryana model of HPSR was the presence of a dedicated and motivated team in National Rural Health Mission (NRHM at state level, many of whom were researchers by previous training. Overall, we conclude by highlighting the need for establishing an institutional mechanism at Central and State level where health service administrators and managers, academicians and researchers working in the field of health system from medical colleges, public health schools, management and technology institutions and social science universities can identify health system research priorities. Increased budgetary allocation for HPSR is required.

  10. Engaging Actors for Integrating Health Policy and Systems Research into Policy Making: Case Study from Haryana State in India

    Directory of Open Access Journals (Sweden)

    Shankar Prinja

    2017-09-01

    Full Text Available Background & objective: Good examples of evidence generation using Health Policy and Systems Research (HPSR in low and middle income countries (LMIC; and its application in policy making are scarce. In this paper, we describe the experience of establishing a system of HPSR from the Haryana state in India, outline how the HPSR is being utilized for policy making and programmatic decision making, and analyse the key factors which have been critical to the implementation and uptake of HPSR. Methods: Multiple methods are employed in this case study, ranging from unstructured in-depth interviews, review of the program and policy documents, and participatory notes from the meetings. The steps towards creation of a knowledge partnership between stakeholders are outlined. Four case studies i.e. development of a plan for universal health care (UHC, nutrition policy, centralized drug procurement system and use of RAPID appraisal method highlight the use of research evidence in agenda setting, policy formulation and policy implementation respectively. Results: Our analysis shows that the most important factor which contributed to Haryana model of HPSR was the presence of a dedicated and motivated team in National Rural Health Mission (NRHM at state level, many of whom were researchers by previous training. Overall, we conclude by highlighting the need for establishing an institutional mechanism at Central and State level where health service administrators and managers, academicians and researchers working in the field of health system from medical colleges, public health schools, management and technology institutions and social science universities can identify health system research priorities. Increased budgetary allocation for HPSR is required.

  11. Case studies of green roof policy from Canada

    Energy Technology Data Exchange (ETDEWEB)

    Marshall, S. [Canada Mortgage and Housing Corp., Ottawa, ON (Canada)

    2006-07-01

    In order to overcome environmental, economic, and social challenges, such as stormwater management, heat island effects, reducing energy use in buildings and increasing amenity space, green roof technology has been a key approach used in many European countries and is gaining acceptance throughout North America as knowledge of the environmental benefits and green roof technology grows. While the conditions, benefits and market forces that have driven green roof development in Europe are not identical to Canada's, lessons can be learned from their experiences. Canadian municipalities that are looking to develop and implement green roof policies and programs will need information on how to tailor policies and programs for specific climate conditions, environmental concerns and regulatory realities. In order to provide Canadian municipal decision-makers with an overview of international and local green roof policies and programs, a green roof policy infrastructure manual was recently completed for the Canada Mortgage and Housing Corporation. Decision-makers can be better informed about which policies may be best suited to meet their specific policy needs by reviewing the motivators and other factors behind existing programs around the world. The manual describes green roof policies in each of 12 different jurisdictions from Canada, the United States, Germany, Switzerland, Singapore, and Japan in terms of local green roof motivators and the steps taken along the continuum of establishing policy. This paper described the progress of some Canadian cities that are moving through six phases of establishing appropriate green roof policies and programs. The six phases were introductory and awareness; community engagement; action plan development and implementation; technical research; program and policy development and continuous improvement.

  12. School-University Partnerships: A Means for the Inclusion of Policy Studies in Music Teacher Education

    Science.gov (United States)

    Hunter, Lisa R.

    2011-01-01

    The need for music educators to become more actively involved in policy issues, including analysis, design, implementation, and research, is critical to the future of music education. Bridging the gap between policy and practice requires a collaborative effort among music professionals. This article explores the inclusive use of policy studies in…

  13. Stochastic modeling of a serial killer.

    Science.gov (United States)

    Simkin, M V; Roychowdhury, V P

    2014-08-21

    We analyze the time pattern of the activity of a serial killer, who during 12 years had murdered 53 people. The plot of the cumulative number of murders as a function of time is of "Devil's staircase" type. The distribution of the intervals between murders (step length) follows a power law with the exponent of 1.4. We propose a model according to which the serial killer commits murders when neuronal excitation in his brain exceeds certain threshold. We model this neural activity as a branching process, which in turn is approximated by a random walk. As the distribution of the random walk return times is a power law with the exponent 1.5, the distribution of the inter-murder intervals is thus explained. We illustrate analytical results by numerical simulation. Time pattern activity data from two other serial killers further substantiate our analysis. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. Natural born killers?: the development of the sexually sadistic serial killer.

    Science.gov (United States)

    Johnson, B R; Becker, J V

    1997-01-01

    Today's society seems enthralled with serial killers in the news and the media. Forensic psychiatrists often interview serial killers after they have been caught. There are retrospective studies and case reports of individuals who have committed sexually sadistic serial murders. However, there exists a dearth of case reports on adolescents who have expressed serious fantasies about becoming serial killer prior to actualizing their fantasy. This article presents nine clinical cases of 14- to 18-year-olds who have clinically significant fantasies of becoming a serial killer. Similarities exist in these adolescent cases when compared with retrospective studies and case reports of serial killers on the role of sexually sadistic fantasies and actual killings. Since it has been established that sexual paraphilias may develop at a young age, one can surmise that sadistic paraphilias may also develop in some adolescents. The question is posed, can we predict which of these adolescents may go on to actually become serial killers? This article focuses on how the sexually sadistic fantasy can eventually be acted out and possible motives for the act to be repeated multiple times. Finally, recommendations are made about assessing and treating a youngster who expresses violent sexually sadistic killing fantasies so that attempts can be made to interrupt the progression to actual killing.

  15. Comparison of the variability of the annual rates of change in FEV1 determined from serial measurements of the pre- versus post-bronchodilator FEV1 over 5 years in mild to moderate COPD: Results of the lung health study

    Directory of Open Access Journals (Sweden)

    Tashkin Donald P

    2012-08-01

    Full Text Available Abstract Background The impact of interventions on the progressive course of COPD is currently assessed by the slope of the annual decline in FEV1 determined from serial measurements of the post-, in preference to the pre-, bronchodilator FEV1. We therefore compared the yearly slope and the variability of the slope of the pre- versus the post-bronchodilator FEV1 in men and women with mild to moderate COPD who participated in the 5-year Lung Health Study (LHS. Methods Data were analyzed from 4484 of the 5887 LHS participants who had measurements of pre- and post-bronchodilator FEV1 at baseline (screening visit 2 and all five annual visits. The annual rate of decline in FEV1 (±SE measured pre- and post-bronchodilator from the first to the fifth annual visit was estimated separately using a random coefficient model adjusted for relevant covariates. Analyses were performed separately within each of the three randomized intervention groups. In addition, individual rates of decline in pre- and post-bronchodilator FEV1 were also determined for each participant. Furthermore, sample sizes were estimated for determining the significance of differences in slopes of decline between different interventions using pre- versus post-bronchodilator measurements. Results Within each intervention group, mean adjusted and unadjusted slope estimates were slightly higher for the pre- than the post-bronchodilator FEV1 (range of differences 2.6-5.2 ml/yr and the standard errors around these estimates were only minimally higher for the pre- versus the post-bronchodilator FEV1 (range 0.05-0.11 ml/yr. Conversely, the standard deviations of the mean FEV1 determined at each annual visit were consistently slightly higher (range of differences 0.011 to 0.035 L for the post- compared to the pre-bronchodilator FEV1. Within each group, the proportion of individual participants with a statistically significant slope was similar (varying by only 1.4 to 2.7% comparing the estimates

  16. Customer Perceived Brand Equity in Measuring Consumption Preference towards Local and Imported Products: A serial Studies on Urban and Suburban Level of Indonesia Society in Greater Jakarta

    Directory of Open Access Journals (Sweden)

    Sri Rahayu

    2012-12-01

    Full Text Available This study generally aims to analyze how the preferences of Indonesian as a customer in consuming local and imported products. The specific purpose of this study is to confirm measurement tools of the customer perceived brand equity, which are product country image, culture, marketing mix, and product quality. The result of this study indicates that Indonesian consider much about the marketing mix and product quality, while not so much considering culture.The product country image on the other hand gives the opposite effect. It is significantly related but has negative impact to the customer preference. This study is expected to provide insight on factors that contribute to form customer preference, consumption, and behavior in consuming local and imported product. It is expected that this study can bring impact in increasing local product competitiveness so that local and imported product could compete equally.

  17. Converting serial networks to Ethernet communications

    Energy Technology Data Exchange (ETDEWEB)

    Rosado, Elroy [Freewave Technologies, Inc., Boulder, CO (United States). Latin America

    2008-07-01

    Many oil and gas producers and pipeline companies find themselves in an awkward position. They have invested millions of dollars in legacy serial communications systems and in most cases, millions more in older SCADA remote terminal units and electronic flow meters. There is a desire throughout most of the industry to convert these systems to Ethernet. This presentation will explore how Ethernet protocol offers advantages over the older serial communications in terms of peer to peer communication, faster polling cycles, and the ability to poll multiple devices at the same time. (author)

  18. Multistage parallel-serial time averaging filters

    International Nuclear Information System (INIS)

    Theodosiou, G.E.

    1980-01-01

    Here, a new time averaging circuit design, the 'parallel filter' is presented, which can reduce the time jitter, introduced in time measurements using counters of large dimensions. This parallel filter could be considered as a single stage unit circuit which can be repeated an arbitrary number of times in series, thus providing a parallel-serial filter type as a result. The main advantages of such a filter over a serial one are much less electronic gate jitter and time delay for the same amount of total time uncertainty reduction. (orig.)

  19. Serial position effects in mild cognitive impairment.

    Science.gov (United States)

    Howieson, Diane B; Mattek, Nora; Seeyle, Adriana M; Dodge, Hiroko H; Wasserman, Dara; Zitzelberger, Tracy; Jeffrey, Kaye

    2011-03-01

    Mild cognitive impairment (MCI) is often associated with the preclinical phase of Alzheimer's disease (AD). Special scoring of word-list recall data for serial position has been suggested to improve discrimination of normal aging from dementia. We examined serial position effects in word-list recall for MCI participants compared to Alzheimer patients and controls. Individuals with MCI, like Alzheimer patients, had a diminished primacy effect in recalling words from a list. No alternative scoring system was better than standard scoring of word-list recall in distinguishing MCI patients from controls. Retention weighted scoring improved the discrimination of MCI and AD groups.

  20. Geo hazard studies and their policy implications in Nicaragua

    Science.gov (United States)

    Strauch, W.

    2007-05-01

    Nicaragua, situated at the Central American Subduction zone and placed in the trajectory of tropical storms and hurricanes, is a frequent showplace of natural disasters which have multiplied the negative effects of a long term socioeconomic crisis leaving Nicaragua currently as the second poorest country of the Americas. In the last years, multiple efforts were undertaken to prevent or mitigate the affectation of the natural phenomena to the country. National and local authorities have become more involved in disaster prevention policy and international cooperation boosted funding for disaster prevention and mitigation measures in the country. The National Geosciences Institution (INETER) in cooperation with foreign partners developed a national monitoring and early warning system on geological and hydro-meteorological phenomena. Geological and risk mapping projects were conducted by INETER and international partners. Universities, NGO´s, International Technical Assistance, and foreign scientific groups cooperated to capacitate Nicaraguan geoscientists and to improve higher education on disaster prevention up to the master degree. Funded by a World Bank loan, coordinated by the National System for Disaster Prevention, Mitigation and Attention (SINAPRED) and scientifically supervised by INETER, multidisciplinary hazard and vulnerability studies were carried out between 2003 and 2005 with emphasis on seismic hazard. These GIS based works provided proposals for land use policies on a local level in 30 municipalities and seismic vulnerability and risk information for each single building in Managua, Capital of Nicaragua. Another large multidisciplinary project produced high resolution air photos, elaborated 1:50,000 vectorized topographic maps, and a digital elevation model for Western Nicaragua. These data, integrated in GIS, were used to assess: 1) Seismic Hazard for Metropolitan Managua; 2) Tsunami hazard for the Pacific coast; 3) Volcano hazard for Telica

  1. CASE STUDY: Tanzania — Competition policy spurs economy-wide ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-12-16

    Dec 16, 2010 ... People often fear for their futures when free-market policies are introduced. ... No matter how well an economy is doing, politicians like to say that for each ... holdings that interfere with legitimate and successful competition.

  2. Agents of Change: Studies on the Policy Environment for Small ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    In Africa, unlike in Mauritius, everybody believes in the principle that a project started by an ...... In practice, however, it represents a tax on all businesses. ...... Zoning policies have proven restrictive to the development of SMEs in Malaysia.

  3. Climate Change, Public Health, and Policy: A California Case Study

    Science.gov (United States)

    Smith, Jason A.

    2018-01-01

    Anthropogenic activity will bring immediate changes and disruptions to the global climate with accompanying health implications. Although policymakers and public health advocates are beginning to acknowledge the health implications of climate change, current policy approaches are lagging behind. We proposed that 4 key policy principles are critical to successful policymaking in this arena: mainstreaming, linking mitigation and adaptation policy, applying population perspectives, and coordination. We explored California’s progress in addressing the public health challenges of climate change in the San Joaquin Valley as an example. We discussed issues of mental health and climate change, and used the San Joaquin Valley of California as an example to explore policy approaches to health issues and climate change. The California experience is instructive for other jurisdictions. PMID:29072936

  4. Climate Change, Public Health, and Policy: A California Case Study.

    Science.gov (United States)

    Ganesh, Chandrakala; Smith, Jason A

    2018-04-01

    Anthropogenic activity will bring immediate changes and disruptions to the global climate with accompanying health implications. Although policymakers and public health advocates are beginning to acknowledge the health implications of climate change, current policy approaches are lagging behind. We proposed that 4 key policy principles are critical to successful policymaking in this arena: mainstreaming, linking mitigation and adaptation policy, applying population perspectives, and coordination. We explored California's progress in addressing the public health challenges of climate change in the San Joaquin Valley as an example. We discussed issues of mental health and climate change, and used the San Joaquin Valley of California as an example to explore policy approaches to health issues and climate change. The California experience is instructive for other jurisdictions.

  5. Memory for serial order across domains: An overview of the literature and directions for future research.

    Science.gov (United States)

    Hurlstone, Mark J; Hitch, Graham J; Baddeley, Alan D

    2014-03-01

    From vocabulary learning to imitating sequences of motor actions, the ability to plan, represent, and recall a novel sequence of items in the correct order is fundamental for many verbal and nonverbal higher level cognitive activities. Here we review phenomena of serial order documented across the verbal, visual, and spatial short-term memory domains and interpret them with reference to the principles of serial order and ancillary assumptions instantiated in contemporary computational theories of memory for serial order. We propose that functional similarities across domains buttress the notion that verbal, visual, and spatial sequences are planned and controlled by a competitive queuing (CQ) mechanism in which items are simultaneously active in parallel and the strongest item is chosen for output. Within the verbal short-term memory CQ system, evidence suggests that serial order is represented via a primacy gradient, position marking, response suppression, and cumulative matching. Evidence further indicates that output interference operates during recall and that item similarity effects manifest during both serial order encoding and retrieval. By contrast, the principles underlying the representation of serial order in the visual and spatial CQ systems are unclear, largely because the relevant studies have yet to be performed. In the spatial domain, there is some evidence for a primacy gradient and position marking, whereas in the visual domain there is no direct evidence for either of the principles of serial order. We conclude by proposing some directions for future research designed to bridge this and other theoretical gaps in the literature.

  6. Optical Storage In China: A Study in Strategic Industrial Policy

    OpenAIRE

    Greg Linden

    2003-01-01

    China’s industrial policy for high-technology industries combines key features of the policies adopted elsewhere in East Asia: judicious opening to foreign investors and support for local firms. However, unlike the developing economies of East Asia, China is a transition economy that already had a relatively well-developed, if somewhat dated, technology base of its own before its opening to outside investors at the end of the 1970s. Although the initial technology level of indiv...

  7. The eyeball killer: serial killings with postmortem globe enucleation.

    Science.gov (United States)

    Coyle, Julie; Ross, Karen F; Barnard, Jeffrey J; Peacock, Elizabeth; Linch, Charles A; Prahlow, Joseph A

    2015-05-01

    Although serial killings are relatively rare, they can be the cause of a great deal of anxiety while the killer remains at-large. Despite the fact that the motivations for serial killings are typically quite complex, the psychological analysis of a serial killer can provide valuable insight into how and why certain individuals become serial killers. Such knowledge may be instrumental in preventing future serial killings or in solving ongoing cases. In certain serial killings, the various incidents have a variety of similar features. Identification of similarities between separate homicidal incidents is necessary to recognize that a serial killer may be actively killing. In this report, the authors present a group of serial killings involving three prostitutes who were shot to death over a 3-month period. Scene and autopsy findings, including the unusual finding of postmortem enucleation of the eyes, led investigators to recognize the serial nature of the homicides. © 2015 American Academy of Forensic Sciences.

  8. Association of serial biochemical markers with acute ischemic stroke: the National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator Stroke Study.

    Science.gov (United States)

    Jauch, Edward C; Lindsell, Christopher; Broderick, Joseph; Fagan, Susan C; Tilley, Barbara C; Levine, Steven R

    2006-10-01

    Biochemical markers of acute neuronal injury may aid in the diagnosis and management of acute ischemic stroke. Serum samples from the National Institute for Neurological Disorders and Stroke (NINDS) recombinant tissue plasminogen activator Stroke Study were analyzed for the presence of 4 biochemical markers of neuronal, glial, and endothelial cell injury. These biochemical markers, myelin basic protein (MBP), neuron-specific enolase (NSE), S100beta, and soluble thrombomodulin, were studied for an association with initial stroke severity, infarct volume, and functional outcome. In the original NINDS study, serum samples were drawn from all patients on presentation to the Emergency Department and at approximately 2 and 24 hours after initiation of study therapy. In this analysis, stored serum samples were available for 359 patients; 107 patients had samples for all 3 time points. Serum marker concentrations were measured by ELISA techniques. We examined the relation between serum concentrations of each marker and the degree of baseline neurological deficit, functional outcome, and infarct size on computed tomography at 24 hours and the effect of fibrinolytic therapy. Higher 24-hour peak concentrations of MBP, NSE, and S100beta were associated with higher National Institutes of Health Stroke Scale baseline scores (r=0.186, P<0.0001; r=0.117, P=0.032; and r=0.263, P<0.0001, respectively). Higher peak concentrations of MBP and S100beta (r=0.209, P<0.0001; r=0.239, P<0.0001) were associated with larger computed tomography lesion volumes. Patients with favorable outcomes had smaller changes in MBP and S100beta (P<0.05) concentrations in the first 24 hours. Soluble thrombomodulin was not associated with any severity or outcome measure. This study corroborates previous work demonstrating correlations of MBP, NSE, and S100beta with clinical and radiographic features in acute stroke. Despite significantly better outcomes in the tissue plasminogen activator-treated group, we

  9. Investigation of Sustainable Energy Policy: Nairobi Case Study

    Science.gov (United States)

    Shengyuan, Y.; Habiyaremye, J. F. L.; Yingying, W.

    2017-07-01

    A plan for actively achieving green energy obligation is a strategic tool for policies that point forward the diminution of the fossil fuel consumption and greenhouse gas (GHG) in conformity with the Paris environment-friendly accords (COP21) and updates of other ecosystem agreements. To achieve the concrete implementation of the sustainable energy strategy (SES) and to accomplish its objectives, an investigation is a critical factor. SES investigation has to consider both the advancement of each particular action and its wide-ranging green effect, which necessitates multiple levels of improvement. In this study, a consolidated eco strategy for evaluating, monitoring and handling the SES via investigation and execution process is established. The city of Nairobi was used as one of the geographical positions to test the effectiveness of this approach and to investigate its robust and weak points. Specifically, benefit-cost analysis, reliability, peer review and general level of participation were renowned as vital tools for attaining a functional SES investigation and for then drafting successful energy guidelines. Some suggestions were put forward to highlight the research and execution methods and to draw a road map of how SES can be strategically placed into practice.

  10. Implementation of Bluetooth serial port based profiles in embedded systems

    Science.gov (United States)

    Liu, Guanglei; Qiu, Zhengding; Wang, Quanping; Gao, Qiang

    2001-10-01

    Bluetooth is a new short-range wireless communication technology developing rapidly in recent years. Bluetooth software architecture consists of stack and profiles. Serial Port Profile (SPP) is an underlying profile that emulates RS232 serial cable connections between two peer devices. Based on SPP, Dial-up Networking (DUN) Profile establishes PPP connection with remote dial-up server, Fax Profile realizes document facsimile function and LAN Access Profile (LAP) provides local area network access service. When it comes to their implementation in embedded systems, there are several challenges such as memory consumption, code efficiency, code reliability, and code portability onto different OS and hardware platforms to be attacked. In this paper, we propose integrated software architecture after discussing the great similarities shared among the three SPP based profiles. Then implementation of the architecture is given, in which OS-dependent and OS-independent parts are clearly separated. Profile interfaces with stack and OS are specified respectively so that the three profiles as a whole can be ported onto various software and hardware platforms easily. As a result, policy of transplanting our implementation onto different platforms is addressed at the end of the paper.

  11. Rethinking Conceptual Definitions of the Criminal Career and Serial Criminality.

    Science.gov (United States)

    Edelstein, Arnon

    2016-01-01

    Since Cesare Lombroso's days, criminology seeks to define, explain, and categorize the various types of criminals, their behaviors, and motives. This aim has theoretical as well as policy-related implications. One of the important areas in criminological thinking focuses chiefly on recidivist offenders who perform large numbers of crimes and/or commit the most dangerous crimes in society (rape, murder, arson, and armed robbery). These criminals have been defined as "habitual offenders," "professional criminals," "career criminals," and "serial offenders." The interest in these criminals is a rational one, given the perception that they present a severe threat to society. The main challenge in this area of research is a conceptual problem that has significant effects across the field. To this day, scholars have reused and misused titles to define and explain different concepts. The aim of this article is 3-fold. First, to review the concepts of criminal career, professional crime, habitual offenses, and seriality with a critical attitude on confusing terms. Second, to propose the redefinition of concepts mentioned previously, mainly on the criminal career. Third, to propose a theoretical model to enable a better understanding of, and serve as a basis for, further research in this important area of criminology. © The Author(s) 2015.

  12. Contemporary Primary Prevention Aspirin Use by Cardiovascular Disease Risk: Impact of US Preventive Services Task Force Recommendations, 2007-2015: A Serial, Cross-sectional Study.

    Science.gov (United States)

    Van't Hof, Jeremy R; Duval, Sue; Walts, Adrienne; Kopecky, Stephen L; Luepker, Russell V; Hirsch, Alan T

    2017-10-03

    No previous study has evaluated the impact of past US Preventive Services Task Force statements on primary prevention (PP) aspirin use in a primary care setting. The aim of this study was to evaluate temporal changes in PP aspirin use in a primary care population, stratifying patients by their 10-year global cardiovascular disease risk, in response to the 2009 statement. This study estimated biannual aspirin use prevalence using electronic health record data from primary care clinics within the Fairview Health System (Minnesota) from 2007 to 2015. A total of 94 270 patient encounters had complete data to estimate a 10-year cardiovascular disease risk score using the 2013 American College of Cardiology/American Heart Association global risk estimator. Patients were stratified into low- (aspirin use averaged 43%. When stratified by low, intermediate and high risk, average PP aspirin use was 41%, 63%, and 73%, respectively. Average PP aspirin use decreased after the publication of the 2009 US Preventive Services Task Force recommendation statement: from 45% to 40% in the low-risk group; from 66% to 62% in the intermediate-risk group; and from 76% to 73% in the high-risk group, before and after the guideline. Publication of the 2009 US Preventive Services Task Force recommendation was not associated with an increase in aspirin use. High risk PP patients utilized aspirin at high rates. Patients at intermediate risk were less intensively treated, and patients at low risk used aspirin at relatively high rates. These data may inform future aspirin guideline dissemination. © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

  13. A Review of Concepts from Policy Studies Relevant for the Analysis of EFA in Developing Countries

    OpenAIRE

    Lall, Marie

    2007-01-01

    This paper aims to give an introduction to the central concepts and the literature of Policy Studies in education. The first part of the paper addresses the questions of what policy is. How is it made and why is it relevant? It looks in particular at the role of the state and the Policy cycle framework which is an analytical tool that helps to analyse how policy is made and later implemented. The second part then focuses on the central concepts. The two main paradigms of education policy stud...

  14. Recalling visual serial order for verbal sequences

    NARCIS (Netherlands)

    Logie, R.H.; Saito, S.; Morita, A.; Varma, S.; Norris, D.

    2016-01-01

    We report three experiments in which participants performed written serial recall of visually presented verbal sequences with items varying in visual similarity. In Experiments 1 and 2 native speakers of Japanese recalled visually presented Japanese Kanji characters. In Experiment 3, native speakers

  15. Advances in Serials Management. Volume 6.

    Science.gov (United States)

    Hepfer, Cindy, Ed.; Gammon, Julia, Ed.; Malinowski, Teresa, Ed.

    In order to further discussion and support constructive change, this volume presents the following eight papers on various dimensions of serials management: (1) "CD-ROMs, Surveys, and Sales: The OSA [Optical Society of America] Experience" (Frank E. Harris and Alan Tourtlotte); (2) "Management and Integration of Electronic Journals into the…

  16. Prospective study of catheter-related central vein thrombosis in home parenteral nutrition patients with benign disease using serial venous Doppler ultrasound.

    Science.gov (United States)

    Cuerda, Cristina; Joly, Francisca; Corcos, Olivier; Concejo, Javier; Puiggrós, Carolina; Gil, Carmen; Pironi, Loris

    2016-02-01

    Catheter-related central vein thrombosis (CRVT) is a severe complication of home parenteral nutrition (HPN) that may be clinically manifest or subclinical. The aims of the study were to prospectively investigate the incidence of CRVT in patients on HPN with benign disease and determine the influence of different variables on this complication. A prospective, multicentre, observational study in the Home Artificial Nutrition-Chronic Intestinal Failure ESPEN group was performed. Patients with benign disease starting HPN or already on HPN after the insertion of a new catheter, were recruited and followed up with Color Doppler Duplex Sonography (CDDS) evaluations at baseline, 1 week, 3, 6 and 12 months after catheter insertion. Fisher's exact test was used to calculate the association of different variables (related to the patient, type of catheter, vascular access, insertion method, catheter care and anticoagulant treatment) with CRVT events. Sixty-two patients (31 males, 31 females) aged 50 ± 19 (19-83) years were included and followed for a median 363 days, with an Inter Quartile Range of 180-365 days, and a total of 16,186 catheter-days. Six patients had previous CRVT and 16 had history of thromboembolic disease (pulmonary and mesenteric). Forty one patients were receiving anticoagulant treatment. Fifty two patients had tunneled catheters and 10 implanted ports. Two patients had symptomatic thrombosis at 3 and 12 months of follow-up (2 and 3 weeks after normal routine CDDS evaluation). The incidence of CRVT was 0.045/catheter/year. CRVT was not significantly associated with any of the variables analyzed. The incidence of CRVT in patients on HPN for benign disease followed by CDDS is low in the first year of catheterization. We did not observe any case of asymptomatic CRVT. Based on our data, CDDS seems to have low effectiveness as a screening tool for CRVT in asymptomatic patients on HPN with benign disease. Copyright © 2015 Elsevier Ltd and European Society for

  17. Serial measurements of serum human placental lactogen (hPL) and serial ultrasound examinations in the evaluation of fetal growth

    DEFF Research Database (Denmark)

    Sørensen, Steen; von Tabouillot, D; Schioler, V

    2000-01-01

    Serial serum hPL measurements and serial ultrasound fetometry were compared in the evaluation of fetal growth by relating these two parameters to size at birth and to clinical factors known to influence size at birth. The data were from a prospective study of 1000 consecutive pregnant women...... considered to be at risk for fetal growth retardation with retrospective analysis. Serum hPL was measured by radioimmunoassay and fetal weight estimated by ultrasound every 3 weeks during the last trimester. hPL values were expressed as multiples of the median (MoM) and linear regression analysis of the h......PL MoM values was carried out for each pregnancy to find the slope of the line (hPL-slope); at least 3 serum hPL values were required. The estimated fetal weight and weight-for-age at birth was expressed in Z-scores. The individual intrauterine growth velocity was calculated by regression analysis...

  18. International standards for fetal growth based on serial ultrasound measurements: the Fetal Growth Longitudinal Study of the INTERGROWTH-21st Project.

    Science.gov (United States)

    Papageorghiou, Aris T; Ohuma, Eric O; Altman, Douglas G; Todros, Tullia; Cheikh Ismail, Leila; Lambert, Ann; Jaffer, Yasmin A; Bertino, Enrico; Gravett, Michael G; Purwar, Manorama; Noble, J Alison; Pang, Ruyan; Victora, Cesar G; Barros, Fernando C; Carvalho, Maria; Salomon, Laurent J; Bhutta, Zulfiqar A; Kennedy, Stephen H; Villar, José

    2014-09-06

    In 2006, WHO produced international growth standards for infants and children up to age 5 years on the basis of recommendations from a WHO expert committee. Using the same methods and conceptual approach, the Fetal Growth Longitudinal Study (FGLS), part of the INTERGROWTH-21(st) Project, aimed to develop international growth and size standards for fetuses. The multicentre, population-based FGLS assessed fetal growth in geographically defined urban populations in eight countries, in which most of the health and nutritional needs of mothers were met and adequate antenatal care was provided. We used ultrasound to take fetal anthropometric measurements prospectively from 14 weeks and 0 days of gestation until birth in a cohort of women with adequate health and nutritional status who were at low risk of intrauterine growth restriction. All women had a reliable estimate of gestational age confirmed by ultrasound measurement of fetal crown-rump length in the first trimester. The five primary ultrasound measures of fetal growth--head circumference, biparietal diameter, occipitofrontal diameter, abdominal circumference, and femur length--were obtained every 5 weeks (within 1 week either side) from 14 weeks to 42 weeks of gestation. The best fitting curves for the five measures were selected using second-degree fractional polynomials and further modelled in a multilevel framework to account for the longitudinal design of the study. We screened 13,108 women commencing antenatal care at less than 14 weeks and 0 days of gestation, of whom 4607 (35%) were eligible. 4321 (94%) eligible women had pregnancies without major complications and delivered live singletons without congenital malformations (the analysis population). We documented very low maternal and perinatal mortality and morbidity, confirming that the participants were at low risk of adverse outcomes. For each of the five fetal growth measures, the mean differences between the observed and smoothed centiles for the 3rd

  19. A longitudinal observational study of brain atrophy rate reflecting four decades of multiple sclerosis: a comparison of serial 1D, 2D, and volumetric measurements from MRI images

    International Nuclear Information System (INIS)

    Martola, Juha; Zhang, Yi; Aspelin, Peter; Kristoffersen Wiberg, Maria; Bergstroem, Jakob; Fredrikson, Sten; Stawiarz, Leszek; Hillert, Jan; Flodmark, Olof; Lilja, Anders; Ekbom, Anders

    2010-01-01

    Multiple sclerosis (MS) has a variable progression with an early onset of atrophy. Individual longitudinal radiological evaluations (over decades) are difficult to perform due to the limited availability of magnetic resonance imaging (MRI) in the past, patients lost in follow-up, and the continuous updating of scanners. We studied a cohort with widespread disease duration at baseline. The observed individual atrophy rates over time of 10 years represented four decades of disease span. Thirty-seven MS patients (age range 24-65 years with disease duration 1-33 years) were consecutively selected and evaluated with MRI at baseline 1995 and in 1996. They were followed up for a decade (mean of 9.25 years, range 7.3-10 years) up to 2003-2005. Brain parenchymal volume and volumes of the supratentorial ventricles were analyzed with semi-automated volumetric measurements at three time points (1995, 1996, and 2003-2005). Volumetric differences were found over shorter periods of time (1-7 months); however, differences vanished by the end of follow-up. A uniform longitudinal decrease in brain volume and increase in ventricle volumes were found. Frontal horn width (1D) correlated strongest to 3D measures. No statistical differences of atrophy rates between MS courses were found. Supratentorial ventricular volumes were associated with disability and this association persisted during follow-up. Despite variable clinical courses, the degenerative effects of MS progression expressed in brain atrophy seem to uniformly progress over longer periods of time. These volumetric changes can be detected using 1D and 2D measurements performed on a routine PACS workstation. (orig.)

  20. The process of changing national malaria treatment policy: lessons from country-level studies.

    Science.gov (United States)

    Williams, Holly Ann; Durrheim, David; Shretta, Rima

    2004-11-01

    Widespread resistance of Plasmodium falciparum parasites to commonly used antimalarials, such as chloroquine, has resulted in many endemic countries considering changing their malaria treatment policy. Identifying and understanding the key influences that affect decision-making, and factors that facilitate or undermine policy implementation, is critical for improving the policy process and guiding resource allocation during this process. A historical review of archival documents from Malaŵi and data obtained from in-depth policy studies in four countries (Tanzania, South Africa, Kenya and Peru) that have changed malaria treatment policy provides important lessons about decision-making, the policy cycle and complex policy environment, while specifically identifying strategies successfully employed to facilitate policy-making and implementation. Findings from these country-level studies indicate that the process of malaria drug policy review should be institutionalized in endemic countries and based on systematically collected data. Key stakeholders need to be identified early and engaged in the process, while improved communication is needed on all levels. Although malaria drug policy change is often perceived to be a daunting task, using these and other proven strategies should assist endemic countries to tackle this challenge in a systematic fashion that ensures the development and implementation of the rational malaria drug policy.

  1. Toward Cultural Policy Studies on Mobility: Reflections on a Study of the Hong Kong Working Holiday Scheme

    Directory of Open Access Journals (Sweden)

    Louis Ho

    2017-05-01

    Full Text Available Cultural policy is predominantly, and practically, considered the sum of a government’s activities with respect to the arts, humanities and heritage. Thus, cultural policy encompasses a much broader range of activities than was traditionally associated with an arts policy. Critical cultural policy studies, then, sees a distinction between ‘explicit’ cultural policies that are manifestly labelled as ‘cultural’, and ‘implicit’ cultural policies that are not labelled as such, but that work to shape cultural experiences. This article considers this explicit/implicit cultural policy distinction through John Urry’s idea of ‘social as mobility’, suggesting that some public policies regarding mobility (such as immigration, international trade and labour policy have led to specific cultural consequences and therefore qualify as implicit cultural policy. Using Hong Kong’s working holiday scheme as a case study, this article explores how an economic policy on temporary immigrant labour involves a deliberate cultural agenda as well as ‘unintentional’ cultural consequences and problematises the fact that cultural policy studies are largely framed by the idea of ‘social as society’.

  2. What Is "Policy" and What Is "Policy Response"? An Illustrative Study of the Implementation of the Leadership Standards for Social Justice in Scotland

    Science.gov (United States)

    Ward, S. C.; Bagley, C.; Lumby, J.; Hamilton, T.; Woods, P.; Roberts, A.

    2016-01-01

    This article examines "policy" and "policy response" through documentary analysis and an illustrative study of policy implementation. Our approach is informed by Foucault's (2009) theory that power relations in society are conditioned by a culturally generated set of ideas, and that these relations contain the space for both…

  3. Abutment region dosimetry for serial tomotherapy

    International Nuclear Information System (INIS)

    Low, Daniel A.; Mutic, Sasa; Dempsey, James F.; Markman, Jerry; Goddu, S. Murty; Purdy, James A.

    1999-01-01

    Purpose: A commercial intensity modulated radiation therapy system (Corvus, NOMOS Corp.) is presently used in our clinic to generate optimized dose distributions delivered using a proprietary dynamic multileaf collimator (DMLC) (MIMiC) composed of 20 opposed leaf pairs. On our accelerator (Clinac 600C/D, Varian Associates, Inc.) each MIMiC leaf projects to either 1.00 x 0.84 or 1.00 x 1.70 cm 2 (depending on the treatment plan and termed 1 cm or 2 cm mode, respectively). The MIMiC is used to deliver serial (axial) tomotherapy treatment plans, in which the beam is delivered to a nearly cylindrical volume as the DMLC is rotated about the patient. For longer targets, the patient is moved (indexed) between treatments a distance corresponding to the projected leaf width. The treatment relies on precise indexing and a method was developed to measure the precision of indexing devices. A treatment planning study of the dosimetric effects of incorrect patient indexing and concluded that a dose heterogeneity of 10% mm -1 resulted. Because the results may be sensitive to the dose model accuracy, we conducted a measurement-based investigation of the consequences of incorrect indexing using our accelerator. Although the indexing provides an accurate field abutment along the isocenter, due to beam divergence, hot and cold spots will be produced below and above isocenter, respectively, when less than 300 deg. arcs were used. A preliminary study recently determined that for a 290 deg. rotation in 1 cm mode, 15% cold and 7% hot spots were delivered to 7 cm above and below isocenter, respectively. This study completes the earlier work by investigating the dose heterogeneity as a function of position relative to the axis of rotation, arc length, and leaf width. The influence of random daily patient positioning errors is also investigated. Methods and Materials: Treatment plans were generated using 8.0 cm diameter cylindrical target volumes within a homogeneous rectilinear film

  4. Mental health policy process: a comparative study of Ghana, South Africa, Uganda and Zambia

    Directory of Open Access Journals (Sweden)

    Kigozi Fred

    2010-08-01

    Full Text Available Abstract Background Mental illnesses are increasingly recognised as a leading cause of disability worldwide, yet many countries lack a mental health policy or have an outdated, inappropriate policy. This paper explores the development of appropriate mental health policies and their effective implementation. It reports comparative findings on the processes for developing and implementing mental health policies in Ghana, South Africa, Uganda and Zambia as part of the Mental Health and Poverty Project. Methods The study countries and respondents were purposively selected to represent different levels of mental health policy and system development to allow comparative analysis of the factors underlying the different forms of mental health policy development and implementation. Data were collected using semi-structured interviews and document analysis. Data analysis was guided by conceptual framework that was developed for this purpose. A framework approach to analysis was used, incorporating themes that emerged from the data and from the conceptual framework. Results Mental health policies in Ghana, South Africa, Uganda and Zambia are weak, in draft form or non-existent. Mental health remained low on the policy agenda due to stigma and a lack of information, as well as low prioritisation by donors, low political priority and grassroots demand. Progress with mental health policy development varied and respondents noted a lack of consultation and insufficient evidence to inform policy development. Furthermore, policies were poorly implemented, due to factors including insufficient dissemination and operationalisation of policies and a lack of resources. Conclusions Mental health policy processes in all four countries were inadequate, leading to either weak or non-existent policies, with an impact on mental health services. Recommendations are provided to strengthen mental health policy processes in these and other African countries.

  5. Determination of motive of serial invaders as a stage of serial murders investigation

    Directory of Open Access Journals (Sweden)

    Davydov A.B.

    2017-04-01

    Full Text Available the article discusses the existing classification of motives of serial murderers. The author provides the classification, which is based on the technique of extreme meanings offered by D.A. Leontyev.

  6. Imaging Cellular Proliferation During Chemo-Radiotherapy: A Pilot Study of Serial 18F-FLT Positron Emission Tomography/Computed Tomography Imaging for Non-Small-Cell Lung Cancer

    International Nuclear Information System (INIS)

    Everitt, Sarah; Hicks, Rodney J.; Ball, David; Kron, Tomas; Schneider-Kolsky, Michal; Walter, Tania; Binns, David; Mac Manus, Michael

    2009-01-01

    Purpose: To establish whether 18 F-3'-deoxy-3'-fluoro-L-thymidine ( 18 F-FLT) can monitor changes in cellular proliferation of non-small-cell lung cancer (NSCLC) during radical chemo-radiotherapy (chemo-RT). Methods and Materials: As part of a prospective pilot study, 5 patients with locally advanced NSCLC underwent serial 18 F-FLT positron emission tomography (PET)/computed tomography (CT) scans during treatment. Baseline 18 F-FLT PET/CT scans were compared with routine staging 18 F-FDG PET/CT scans. Two on-treatment 18 F-FLT scans were performed for each patient on Days 2, 8, 15 or 29, providing a range of time points for response assessment. Results: In all 5 patients, baseline lesional uptake of 18 F-FLT on PET/CT corresponded to staging 18 F-FDG PET/CT abnormalities. 18 F-FLT uptake in tumor was observed on five of nine (55%) on-treatment scans, on Days 2, 8 and 29, but not Day 15. A 'flare' of 18 F-FLT uptake in the primary tumor of one case was observed after 2 Gy of radiation (1.22 x baseline). The remaining eight on-treatment scans demonstrated a mean reduction in 18 F-FLT tumor uptake of 0.58 x baseline. A marked reduction of 18 F-FLT uptake in irradiated bone marrow was observed for all cases. This reduction was observed even after only 2 Gy, and all patients demonstrated a complete absence of proliferating marrow after 10 Gy. Conclusions: This proof of concept study indicates that 18 F-FLT uptake can monitor the distinctive biologic responses of epithelial cancers and highly radiosensitive normal tissue changes during radical chemo-RT. Further studies of 18 F-FLT PET/CT imaging during therapy may suggest that this tracer is useful in developing response-adapted RT for NSCLC.

  7. Serial rotatostereography - A new diagnostic method

    International Nuclear Information System (INIS)

    Ottomo, Michinori; Nakanishi, Takeshi.

    1986-01-01

    In the previous study using cine, a cine film stereoprojector showed the adjacent two frames of cine film simultaneously, such as frames 1 and 2, 2 and 3, 3 and 4, and so on, consecutively. Because some intracranial lesions require emergency surgery immediately after angiography, a real time display method of serial rotatostereography was necessary. In order to show the consecutive adjacent two frames of a video disc simultaneously, using the same method as with the cine stereoprojector, a video disc recorder (VDR) (VM-1000M) and two video memories (Image Σ) were required. This VDR has the ability of advancing, stopping, and reversing the display of memories. A control unit was manufactured in order to display these memories advancing and reversing continuously. As a result of this continuous semirotation stereo display, the anteroposterior projection was reversed, showing the posteroanterior view during ''reversing mode''. Thus a lead relay circuit was manufactured to prevent this phenomenon. Recording was done using a memory disc recorder (FOM 2200F), which has the ability of recording 10,000 frames per disc. Each frame can also be recorded on imaging film using O · X Multi Camera 400X. Finally, stereoscopic views of cerebral circulation, using a single injection of contrast media and rapid rotation of the gantry, were obtained using two cathode-ray tubes (CRTs) and a stereoviewer (Continuous Semi-rotation Classical Stereo Display Method). Stereoscopic views were also obtained using a single CRT, which displayed the images in a semirotating fashion similar to a oscillating fan head (Continuous Semi-rotation New Stereo Display Method). (J.P.N.)

  8. Serial-omics characterization of equine urine.

    Directory of Open Access Journals (Sweden)

    Min Yuan

    Full Text Available Horse urine is easily collected and contains molecules readily measurable using mass spectrometry that can be used as biomarkers representative of health, disease or drug tampering. This study aimed at analyzing microliter levels of horse urine to purify, identify and quantify proteins, polar metabolites and non-polar lipids. Urine from a healthy 12 year old quarter horse mare on a diet of grass hay and vitamin/mineral supplements with limited pasture access was collected for serial-omics characterization. The urine was treated with methyl tert-butyl ether (MTBE and methanol to partition into three distinct layers for protein, non-polar lipid and polar metabolite content from a single liquid-liquid extraction and was repeated two times. Each layer was analyzed by high performance liquid chromatography-high resolution tandem mass spectrometry (LC-MS/MS to obtain protein sequence and relative protein levels as well as identify and quantify small polar metabolites and lipids. The results show 46 urine proteins, many related to normal kidney function, structural and circulatory proteins as well as 474 small polar metabolites but only 10 lipid molecules. Metabolites were mostly related to urea cycle and ammonia recycling as well as amino acid related pathways, plant diet specific molecules, etc. The few lipids represented triglycerides and phospholipids. These data show a complete mass spectrometry based-omics characterization of equine urine from a single 333 μL mid-stream urine aliquot. These omics data help serve as a baseline for healthy mare urine composition and the analyses can be used to monitor disease progression, health status, monitor drug use, etc.

  9. How Nutrition Sensitive Are the Nutrition Policies of New Zealand Food Manufacturers? A Benchmarking Study

    Science.gov (United States)

    Doonan, Rebecca

    2017-01-01

    Nutrition sensitive policy addresses the underlying determinants of nutrition-related disease and is a powerful tool in reducing the incidence of non-communicable disease. Some members of the food industry have long standing commitments to health-oriented nutrition policies. The aim of this study was to develop and apply a balanced scorecard of nutrition sensitive indicators to the policies of influential New Zealand food and beverage manufacturers and explore factors affecting policy processes. Results: The average nutrition sensitivity score of the twenty influential manufacturers policies was 42 against a benchmark of 75. Some manufacturers performed well whilst others had substantial scope for improvement, the largest variation was in policy development and implementation, whereas nutrition quality was relatively consistent. Manufacturers with written policy (n = 11) scored on average three times higher than their counterparts with verbal policy. The value a manufacturer placed on nutrition influenced whether formal nutrition policies were developed. The reputational risk of failing to deliver on publicly declared nutrition commitments acted as an informal accountability mechanism. We conclude the balanced scorecard offers a useful tool for assessing the nutrition sensitivity of influential food and beverage manufacturers’ policies. Our results provide a baseline for repeat assessments of the nutrition sensitivity of food manufacturers’ policies. PMID:29257049

  10. How Nutrition Sensitive Are the Nutrition Policies of New Zealand Food Manufacturers? A Benchmarking Study

    Directory of Open Access Journals (Sweden)

    Rebecca Doonan

    2017-12-01

    Full Text Available Nutrition sensitive policy addresses the underlying determinants of nutrition-related disease and is a powerful tool in reducing the incidence of non-communicable disease. Some members of the food industry have long standing commitments to health-oriented nutrition policies. The aim of this study was to develop and apply a balanced scorecard of nutrition sensitive indicators to the policies of influential New Zealand food and beverage manufacturers and explore factors affecting policy processes. Results: The average nutrition sensitivity score of the twenty influential manufacturers policies was 42 against a benchmark of 75. Some manufacturers performed well whilst others had substantial scope for improvement, the largest variation was in policy development and implementation, whereas nutrition quality was relatively consistent. Manufacturers with written policy (n = 11 scored on average three times higher than their counterparts with verbal policy. The value a manufacturer placed on nutrition influenced whether formal nutrition policies were developed. The reputational risk of failing to deliver on publicly declared nutrition commitments acted as an informal accountability mechanism. We conclude the balanced scorecard offers a useful tool for assessing the nutrition sensitivity of influential food and beverage manufacturers’ policies. Our results provide a baseline for repeat assessments of the nutrition sensitivity of food manufacturers’ policies.

  11. How Nutrition Sensitive Are the Nutrition Policies of New Zealand Food Manufacturers? A Benchmarking Study.

    Science.gov (United States)

    Doonan, Rebecca; Field, Penny

    2017-12-19

    Nutrition sensitive policy addresses the underlying determinants of nutrition-related disease and is a powerful tool in reducing the incidence of non-communicable disease. Some members of the food industry have long standing commitments to health-oriented nutrition policies. The aim of this study was to develop and apply a balanced scorecard of nutrition sensitive indicators to the policies of influential New Zealand food and beverage manufacturers and explore factors affecting policy processes. The average nutrition sensitivity score of the twenty influential manufacturers policies was 42 against a benchmark of 75. Some manufacturers performed well whilst others had substantial scope for improvement, the largest variation was in policy development and implementation, whereas nutrition quality was relatively consistent. Manufacturers with written policy ( n = 11) scored on average three times higher than their counterparts with verbal policy. The value a manufacturer placed on nutrition influenced whether formal nutrition policies were developed. The reputational risk of failing to deliver on publicly declared nutrition commitments acted as an informal accountability mechanism. We conclude the balanced scorecard offers a useful tool for assessing the nutrition sensitivity of influential food and beverage manufacturers' policies. Our results provide a baseline for repeat assessments of the nutrition sensitivity of food manufacturers' policies.

  12. A serial founder effect model for human settlement out of Africa

    OpenAIRE

    Deshpande, Omkar; Batzoglou, Serafim; Feldman, Marcus W.; Luca Cavalli-Sforza, L.

    2008-01-01

    The increasing abundance of human genetic data has shown that the geographical patterns of worldwide genetic diversity are best explained by human expansion out of Africa. This expansion is modelled well by prolonged migration from a single origin in Africa with multiple subsequent serial founding events. We discuss a new simulation model for the serial founder effect out of Africa and compare it with results from previous studies. Unlike previous models, we distinguish colonization events fr...

  13. Accountability Policies at Schools: A Study of Path Analysis

    Science.gov (United States)

    Erdag, Coskun

    2017-01-01

    Turkey is now on its way to reforming compulsory education and having a more effective and efficient education system by creating more accountable schools. This research has been designed in a causative pattern to discover the effects of external academic performance pressures on school accountability policies and school accountability responses…

  14. Social policy and drug dependence: an historical case study.

    Science.gov (United States)

    Smart, C

    1985-11-01

    A detailed examination is presented of the background to the reports and policy developments concerning drug dependence which emerged in Britain during the 1960s. Analysis of documents and interviews with policy makers, officials and doctors involved in the events of the period, reveal that explanatory models in terms of 'moral panic' or 'power struggle' tend to oversimplify the complex processes involved. The role in policy formation of the media, government departments and groups within the medical profession is considered. The patterns of conflict and convergence are seen to overlap simple lines of 'interest'--we find conflict within the medical profession, convergence between the Home Office (legal) and elements of the medical professions (medical). The resulting legal and institutional framework involved only loose guidelines from the centre about treatment, and the shape of policy was determined by individual doctors in the new hospital treatment centres. The apparent re-run of the 1960s being staged in the 1980s will require detailed research in the future in order to avoid superficial comparisons.

  15. China on the Mekong: Legitimacy Imperatives and Policy Case Studies

    Science.gov (United States)

    2013-12-01

    David Kang proposes that conventional theories might prove insufficient for analyzing China’s rise due to its unique cultural and historical...modernization targets. The first, cautious reforms reversed Mao’s collectivist policies to enliven agricultural and basic industrial sectors.36...discussion is heavily one-sided.70 Second, Southeast Asian countries often prioritize sovereignty, autonomy , and economic engagement with larger

  16. Comparative Study on Rural Electrification Policies in Emerging Economies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    Brazil, China, India and South Africa have each worked to improve access to electricity services. While many of the challenges faced by these countries are similar, the means of addressing them varied in their application and effectiveness. This report analyses the four country profiles, determining the pre-requisites to successful rural electrification policies.

  17. A study on the migration policy in ancient China.

    Science.gov (United States)

    Wang, Y

    1995-01-01

    During the Chinese dynasties of Sui and Tang, neighboring minority groups were forced to migrate to less settled areas of China. During the Song dynasty (960-1279) the Han government lost control of neighboring ethnic groups. Ethnically dominated states on their own expanded to the hinterlands, formed the national governments of Yuan and Qing, and established the local power of Liao and Jin in Han-dominated areas. During the Han dynasty the movement of minorities fulfilled the purpose of helping cultivate undeveloped land. The Han governments of feudal China held compulsory migration policies and policies encouraging minorities to move to less inhabited places. Han governments prior to the Tang and Song dynasties held policies favorable to minority settlements. During the Tang dynasty land was given to minority settlers. During the Song dynasty the Han government held a policy which prohibited taxation and harassment of new minority settlers. Minorities gained improved living conditions and the government achieved pacification. Resettlement of minorities either from forced or voluntary migration facilitated communication with the Han and promoted the exchange of culture, but also intensified ethnic conflict. The reason for the ethnic conflict was a question of control. Ethnic governments encouraged in-migration and adopted policies of compulsory and voluntary migration. Ethnic minorities in the north and west practiced mainly compulsory migration. Ethnic conflict in the Qin and Han dynasties occurred between the Han and the Huns. During the Eastern Jin and Northern dynasties minority governments captured Han and other ethnic groups. The rule of minority government was strengthened by voluntary migration. The frequent power shifts in ancient China contributed to the blending of Chinese nationalities.

  18. Kinematics/statics analysis of a novel serial-parallel robotic arm with hand

    International Nuclear Information System (INIS)

    Lu, Yi; Dai, Zhuohong; Ye, Nijia; Wang, Peng

    2015-01-01

    A robotic arm with fingered hand generally has multi-functions to complete various complicated operations. A novel serial-parallel robotic arm with a hand is proposed and its kinematics and statics are studied systematically. A 3D prototype of the serial-parallel robotic arm with a hand is constructed and analyzed by simulation. The serial-parallel robotic arm with a hand is composed of an upper 3RPS parallel manipulator, a lower 3SPR parallel manipulator and a hand with three finger mechanisms. Its kinematics formulae for solving the displacement, velocity, acceleration of are derived. Its statics formula for solving the active/constrained forces is derived. Its reachable workspace and orientation workspace are constructed and analyzed. Finally, an analytic example is given for solving the kinematics and statics of the serial-parallel robotic arm with a hand and the analytic solutions are verified by a simulation mechanism.

  19. Kinematics/statics analysis of a novel serial-parallel robotic arm with hand

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Yi; Dai, Zhuohong; Ye, Nijia; Wang, Peng [Yanshan University, Hebei (China)

    2015-10-15

    A robotic arm with fingered hand generally has multi-functions to complete various complicated operations. A novel serial-parallel robotic arm with a hand is proposed and its kinematics and statics are studied systematically. A 3D prototype of the serial-parallel robotic arm with a hand is constructed and analyzed by simulation. The serial-parallel robotic arm with a hand is composed of an upper 3RPS parallel manipulator, a lower 3SPR parallel manipulator and a hand with three finger mechanisms. Its kinematics formulae for solving the displacement, velocity, acceleration of are derived. Its statics formula for solving the active/constrained forces is derived. Its reachable workspace and orientation workspace are constructed and analyzed. Finally, an analytic example is given for solving the kinematics and statics of the serial-parallel robotic arm with a hand and the analytic solutions are verified by a simulation mechanism.

  20. Reaction kinetics in open reactors and serial transfers between closed reactors

    Science.gov (United States)

    Blokhuis, Alex; Lacoste, David; Gaspard, Pierre

    2018-04-01

    Kinetic theory and thermodynamics of reaction networks are extended to the out-of-equilibrium dynamics of continuous-flow stirred tank reactors (CSTR) and serial transfers. On the basis of their stoichiometry matrix, the conservation laws and the cycles of the network are determined for both dynamics. It is shown that the CSTR and serial transfer dynamics are equivalent in the limit where the time interval between the transfers tends to zero proportionally to the ratio of the fractions of fresh to transferred solutions. These results are illustrated with a finite cross-catalytic reaction network and an infinite reaction network describing mass exchange between polymers. Serial transfer dynamics is typically used in molecular evolution experiments in the context of research on the origins of life. The present study is shedding a new light on the role played by serial transfer parameters in these experiments.

  1. Alur Kerja Tahap Produksi Karakter Animasi Serial 3D Menggunakan Perangkat Lunak Maxon Cinema 4D

    Directory of Open Access Journals (Sweden)

    Ardiyan Ardiyan

    2011-04-01

    Full Text Available 3D Animation serial for television needs have been showed in the national television program, especially fantasy theme and educational program for children. There are so many and sequential needs which tricked by instant and high quality production so the work flow in creating 3D animation serial are facilitating the producers. The article will explain specifically how the software of Maxon Cinema 4D in process production in 3D animation serial. The article will also clarify and focus on how the work flow of Maxon Cinema 4D software in processing production and post-production stages. The writer does research including audio visual tutorial, end-result comparison and rendering time between some software, self-observation of work flow in creating 3D animation serial using Maxon Cinema 4D software and digital literature study (e-book.  

  2. Spatial attention interacts with serial-order retrieval from verbal working memory.

    Science.gov (United States)

    van Dijck, Jean-Philippe; Abrahamse, Elger L; Majerus, Steve; Fias, Wim

    2013-09-01

    The ability to maintain the serial order of events is recognized as a major function of working memory. Although general models of working memory postulate a close link between working memory and attention, such a link has so far not been proposed specifically for serial-order working memory. The present study provided the first empirical demonstration of a direct link between serial order in verbal working memory and spatial selective attention. We show that the retrieval of later items of a sequence stored in working memory-compared with that of earlier items-produces covert attentional shifts toward the right. This observation suggests the conceptually surprising notion that serial-order working memory, even for nonspatially defined verbal items, draws on spatial attention.

  3. Analysis of the decision-support function of policy assessment in real-world policy making in the field of poverty and social inequalities. Case study on migrant integration policies in the Brussels-Capital Region

    International Nuclear Information System (INIS)

    Feyaerts, Gille; Deguerry, Murielle; Deboosere, Patrick; De Spiegelaere, Myriam

    2017-01-01

    Despite its high potential to support decision-making, the role of policy assessment in real-world policy making in the field of poverty and social inequalities remains largely questioned. In this study, we analyse policy assessment's role in a context of real-world policymaking, by means of a case study on a legislative proposal on integration policy for immigrant newcomers in the Brussels-Capital Region, for which we evaluate the potential effects on poverty and social inequalities. We first analyse the policy process surrounding the policy proposal – a process that is often treated as a black box within policy assessment research. Understanding the factors that influence and determine the decision-making process, enables us to gain insight into the potential decision-support function(s). Second, we develop an approach to policy assessment that aims to fully exploit its potential to contribute to the functions of both instrumental and conceptual learning. For this purpose, we propose to introduce the approach of realist evaluation and to focus on evaluating the underlying policy intervention theory from the perspective of poverty and social inequalities. Finally, we illustrate this new approach and its added value by applying it to the legislative proposal on integration policy and analyse its contribution to policy-oriented learning. - Highlights: •The field of policy assessment should draw on insights from policy studies. •We unpacked the policymaking black-box to identify the mechanisms of policy change. •The policy process is driven by an interaction of ideas, interests and institutions. •Policy assessment's potential lies in both instrumental and conceptual learning. •We propose to integrate realist evaluation's logic of inquiry within policy assessment.

  4. Scoping Study. Linking RE Promotion Policies with International Carbon Trade (LINK)

    Energy Technology Data Exchange (ETDEWEB)

    Castro, Paula; Hayashi, Daisuke; Kristiansen, Kjell Olav; Michaelowa, Axel; Stadelmann, Martin

    2011-06-15

    Implementing national policies may threaten the eligibility of renewable energy projects for Clean Development Mechanism/Joint Implementation (CDM/JI), thus reducing international development financing. Countries hence need to be very careful when crafting their national promotion policies. The objectives of the Renewable Energy Technology Deployment (IEA-RETD) project were to perform a scoping study on the interplay between national Renewable Energy (RE) promotion policies and international carbon trade. The study summarizes the ongoing discussion, describes the main barriers that may hinder -- or at least not sufficiently support -- the implementation of national RE promotion policies, and provides suggestions for removing these barriers.

  5. A study on the role of influence group in public policy making

    Directory of Open Access Journals (Sweden)

    Abbas Monavarian

    2014-09-01

    Full Text Available Nowadays, learning more about influence groups on public policy making is one of most important subjects of management science. Governments are the primary sources for public policy making but influenced groups participate indirectly and while they remain out of power, they put pressure on many decisions. Some of participants in public policy making are not influenced groups but mostly, due to their participation in policy public making matter are called influenced groups. This research, from practical research purpose and method view, is a descriptive research and survey branch. The study investigates the effect of university based Iranian Sociological Association on public policy making. The study designs a questionnaire in Likert scale and distributes it among some experts. The results of our survey indicate that that Iranian Sociological Association could influence on public policy making through elite and prominent leaders, self-knowledge and information, elective campaigns, stimulation and connecting with people and other groups.

  6. Comparative Analysis of Institutional Policy Definitions of Plagiarism: A Pan-Canadian University Study

    Science.gov (United States)

    Eaton, Sarah Elaine

    2017-01-01

    This article shares the findings of a study investigating institutional policy definitions of plagiarism at twenty English-speaking Canadian universities. The types of primary sources consulted for this study included: (1) university academic calendars for 2016-2017, (2) institutional policies on academic misconduct, and (3) student academic codes…

  7. Educating Adolescents in the Context of Section 504 Policy: a Comparative Study of Two Middle Schools

    OpenAIRE

    Taylor, Martha Asterilla

    2002-01-01

    EDUCATING ADOLESCENTS IN THE CONTEXT OF SECTION 504 POLICY: A COMPARATIVE STUDY OF TWO MIDDLE SCHOOLS By Martha Asterilla Taylor Jean B. Crockett, Ph.D. Chairperson Educational Leadership and Policy Studies (ABSTRACT) Section 504 "prohibits discrimination against persons with disabilities by school districts receiving federal financial assistance" (First & Curcio, 1993, p.33). In public schools, eligible students receive an Individualized Accommodation Plan (IA...

  8. Homework policy review: A case study of a public school in the ...

    African Journals Online (AJOL)

    A key concern today is the question of homework in our nation's public schools. In this study, an investigation was conducted with the first no-homework policy, which has been introduced in one of the primary schools in the Western Cape. This study seeks to determine whether a no-homework policy will validate a positive ...

  9. Homework Policy Review: A Case Study of A Public School in the Western Cape Province

    Science.gov (United States)

    Pfeiffer, Verbra

    2018-01-01

    A key concern today is the question of homework in our nation's public schools. In this study, an investigation was conducted with the first no-homework policy, which has been introduced in one of the primary schools in the Western Cape. This study seeks to determine whether a no-homework policy will validate a positive or negative effect on…

  10. Sensing the Opaque : Seriality and the Aesthetics of Televisual Form

    NARCIS (Netherlands)

    Dasgupta, S.; Kelleter, F.

    2017-01-01

    Recent work on TV seriality focuses on the deference of meaning through narrative extension. Contemporary seriality, it has been argued, exploits this expanding textuality to construct complicated narratives that tip the pleasures of seriality toward detecting the meaning of the plot's

  11. Measuring Efficacy of Information Security Policies : A Case Study of UAE based company

    OpenAIRE

    Qureshi, Muhammad Sohail

    2012-01-01

    Nowadays information security policies are operative in many organizations. Currently few organizations take the pain of verifying the efficacy of these policies. Different standards and procedures exist about methods of measuring efficacy of information security policies. Choosing and implementing them depends mainly on the key performance indicators (KPIs) and key risk indicators (KRIs) of any particular organization. This thesis is a case study of an organization in United Arab Emirates (U...

  12. Green electricity policies in the United States: case study

    International Nuclear Information System (INIS)

    Menz, Fredric C.

    2005-01-01

    While there has been interest in promoting the use of renewable energy in electricity production for a number of years in the United States, the market share of non-hydro renewable energy sources in electricity production has remained at about 2 percent over the past decade. The paper reviews the principal energy resources used for electricity production, considers the changing regulatory environment for the electricity industry, and describes government policies that have been used to promote green electricity in the United States, with an emphasis on measures adopted by state governments. Factors influencing the development of green power markets are also discussed, including underlying economic issues, public policy measures, the regulatory environment, external costs, and subsidies. Without significant increases in fossil fuel prices, much more stringent environmental regulations, or significant changes in electricity customer preferences, green electricity markets are likely to develop slowly in the United States

  13. Serial SPECT in children with partial epilepsy

    International Nuclear Information System (INIS)

    Hosoya, Machiko; Ushiku, Hideo

    1995-01-01

    We performed serial single-photon emission CT (SPECT) with N-isopropyl-p-( 123 I)-Iodoamphetamine to measure the regional cerebral blood flow (rCBF) in 15 children with partial epilepsy. SPECT showed focal changes in 14 cases. Ten cases had abnormalities in the initial SPECT and another four cases in the second test. The cases with normal rCBF in initial SPECT had been tested in an early phase after the onset, and then decreased rCBF were observed in the second SPECT. The cases with both abnormal rCBF in the initial SPECT and improved rCBF in the second SPECT showed good prognosis in clinico-electrophysiological evolutions. In cases with abnormal changes of rCBF in the second SPECT, clinical prognosis was found to be not so good. These findings suggest that serial SPECT may be used to follow the course of epilepsy. (author)

  14. [Personality disorders, psychopathy and serial killers].

    Science.gov (United States)

    Morana, Hilda C P; Stone, Michael H; Abdalla-Filho, Elias

    2006-10-01

    To illustrate the basic characteristics of several specific personality disorders, focusing mainly in antisocial personality disorder. The differences between antisocial personality disorder and psychopathy are highlighted. Serial killers and its psychopathic aspects are also discussed. A bibliographic review was completed in order to outline convergences and divergences among different authors about this controversial issue, especially those concerning the possibility of treatment. While anti-social personality disorder is a medical diagnosis, the term "psychopathy" (which belongs to the sphere of forensic psychiatry) may be understood as a "legal diagnosis". It is not still possible to identify an effective treatment for serial killers. Personality disorders, especially of the antisocial type, still represent a formidable challenge to forensic psychiatry today. Questions as yet unanswered include the best and most humane place for patients with this condition and the nature of a standardised treatment recommendation.

  15. AN INVESTIGATIVE STUDY REGARDING SMES SPECIFIC ACCOUNTING POLICIES

    Directory of Open Access Journals (Sweden)

    Mester Ioana Teodora

    2011-07-01

    Full Text Available In this paper we intend to continue the research regarding the enterprise accounting policies and the manner in which these are perceived by the practitioner accountants, preparers of financial statements. This time, in order to carry out the research, we made up a new questionnaire applied to the same sample, containing a number of 100 SMEs in Bihor County, selected according to the criterion of the average number of employees and that of the level of net turnover at the end of 2008. Continuing previous conducted research we have investigated this time the specific accounting policies of the sampled SMEs from Bihor County and the way these policies are understood by practitioners and implemented in order to prepare financial statements. Surprisingly, we have found that only 93.33% of the respondents agree that the elements presented in the annual financial statements of the entity are evaluated in accordance with the general accounting principles stipulated in Order 3055/2009, according to the accrual accounting. Half of the people interviewed had in view all four qualities of accounting information (intelligibility, relevance, credibility, comparability in drawing up the annual financial statements, and most of them (56.67% are not aware of the possibility to use a significance threshold (10%-15% of the total value of that particular category of assets, liabilities, expenditure, income and results for an as faithful as possible presentation of information in the balance sheet and in the profit and loss account.

  16. Evaluating Evaluation Systems: Policy Levers and Strategies for Studying Implementation of Educator Evaluation. Policy Snapshot

    Science.gov (United States)

    Matlach, Lauren

    2015-01-01

    Evaluation studies can provide feedback on implementation, support continuous improvement, and increase understanding of evaluation systems' impact on teaching and learning. Despite the importance of educator evaluation studies, states often need support to prioritize and fund them. Successful studies require expertise, time, and a shared…

  17. A Study on Portfolio of Domestic Policies and Measures for GHG emission Abatement

    Energy Technology Data Exchange (ETDEWEB)

    Lim, J.K. [Korea Energy Economics Institute, Euiwang (Korea)

    2001-11-01

    After the climate change negotiation reaches an agreement in COP7, the next main issue to be addressed is the way of involvement of developing countries in emission abatement commitments and the development of domestic policies and measures to achieve GHG emission reduction target. Many Annex I countries have developed and implemented policies and measures to achieve its quantified GHG emission reduction target. The purpose of this paper is to propose a portfolio of policies and measures, that is, which policies and measures Korea will have to take in preparing future commitment for GHG emission reduction as well as in strengthening mitigation of climate change. Various policies and measures can be used, such as regulations, economic instruments, and covenants, etc., but it is desirable to implement them in some portfolio, taking advantage of their characteristics. Among the possible policies and measures, this study found that economic instruments such as carbon tax and domestic emissions trading have attracted considerable interest recently due to their cost effectiveness. This study also found that, in practice, many developed countries have used these policy instruments in achieving their quantified GHG emission reduction target. In order to develop a portfolio of policies and measures, the comprehension of the features of each policy and measure and the synergetic reconciliation with other objectives than climate change is important. (author). 82 refs., 11 figs., 31 tabs.

  18. Correlating tumor metabolic progression index measured by serial FDG PET-CT, apparent diffusion coefficient measured by magnetic resonance imaging (MRI) and blood genomics to patient’s outcome in advanced colorectal cancer: the CORIOLAN study

    International Nuclear Information System (INIS)

    Deleporte, Amelie; Charette, Nicolas; Machiels, Godelieve; Piccart, Martine; Flamen, Patrick; Hendlisz, Alain; Paesmans, Marianne; Garcia, Camilo; Vandeputte, Caroline; Lemort, Marc; Engelholm, Jean-Luc; Hoerner, Frederic; Aftimos, Philippe; Awada, Ahmad

    2014-01-01

    Metastatic colorectal cancer (mCRC) may present various behaviours that define different courses of tumor evolution. There is presently no available tool designed to assess tumor aggressiveness, despite the fact that this is considered to have a major impact on patient outcome. CORIOLAN is a single-arm prospective interventional non-therapeutic study aiming mainly to assess the natural tumor metabolic progression index (TMPI) measured by serial FDG PET-CT without any intercurrent antitumor therapy as a prognostic factor for overall survival (OS) in patients with mCRC. Secondary objectives of the study aim to test the TMPI as a prognostic marker for progression-free survival (PFS), to assess the prognostic value of baseline tumor FDG uptake on PFS and OS, to compare TMPI to classical clinico-biological assessment of prognosis, and to test the prognostic value on OS and PFS of MRI-based apparent diffusion coefficient (ADC) and variation of vADC using voxel-based diffusion maps. Additionally, this study intends to identify genomic and epigenetic factors that correlate with progression of tumors and the OS of patients with mCRC. Consequently, this analysis will provide information about the signaling pathways that determine the natural and therapy-free course of the disease. Finally, it would be of great interest to investigate whether in a population of patients with mCRC, for which at present no known effective therapy is available, tumor aggressiveness is related to elevated levels of circulating tumor cells (CTCs) and to patient outcome. Tumor aggressiveness is one of the major determinants of patient outcome in advanced disease. Despite its importance, supported by findings reported in the literature of extreme outcomes for patients with mCRC treated with chemotherapy, no objective tool allows clinicians to base treatment decisions on this factor. The CORIOLAN study will characterize TMPI using FDG-PET-based metabolic imaging of patients with chemorefractory m

  19. Characterization and spatial relationships of the hepatic vascular-biliary tracts, and their associated pancreocytes and macrophages, in the model fish guppy (Poecilia reticulata): A study of serial sections by light microscopy.

    Science.gov (United States)

    Sousa, Sisandra; Rocha, Maria J; Rocha, Eduardo

    2018-02-01

    The guppy is a tropical fish that has been used as an experimental model organism in science. It is a species well adapted to the natural environment and that can support adverse environmental conditions, and so, at occasions, its presence can be indicative of environmental disturbances. Moreover, as the liver is very important when studying fish diseases, the knowledge of normal microanatomy is essential to assess histological changes, e.g., related to environmental change or toxic pollutants. The target organ of this histological study is the liver. The main objective is to contribute to the identification of anatomical and structural variations of this organ in different teleost species. We studied the distribution and spatial organization of the different types of blood vessels and biliary ducts and the relationships between them are established. For this, each liver was totally sectioned and the serial sections inspected in detail. The guppy liver presented intra-hepatic pancreatic tissue and so reported its association with the vascular and biliary elements. We observed that the input of afferent vessels (i.e., bringing blood into the liver) occur not only in the hilum but pierce and enter the organ at various points. Within the liver, venous vessels and bile ducts are seen, isolated or associated as venous-arteriolar tracts (VAT), and venous-biliary- arteriolar tracts (VBAT). Sometimes, pancreocytes appear within the liver surrounding isolated veins, forming venous tract with pancreatic acini (VT-P), or dual associations with afferent vessels, forming venous-arteriolar tracts with pancreatic acini (VAT-P). Intrahepatic pancreatic ducts were tiny and rare, putting in question the functional role of the acini. Contrary to other fish species, we did not spot isolated arterioles and associations between these and biliary ducts (BAT).We found aggregates of macrophages, namely associated with afferent and efferent (i.e., draining blood out) venous vessels; the

  20. REGIONAL TRADE AGREEMENTS AND COMPETITION POLICY. CASE STUDY: EU, ASEAN AND NAFTA

    Directory of Open Access Journals (Sweden)

    Fora Andreea-Florina

    2014-07-01

    Full Text Available The large number of regional trade agreements notified to the World Trade Organization (WTO significantly influenced the flow of world trade. By April 2014 there had been notified 583 regional trade agreements to the WTO, of which only 379 are in force. The objective of this paper is to highlight the importance of regional trade agreements in world trade, especially the importance of establishing a regional competition policy in these agreements. The research methodology used is the analysis of legislation governing preferential trade agreements at the level of WTO, the collection and interpretation of statistical data provided by the WTO Secretariat, the case study, namely the study of literature. The paper is structured in three parts. The first part of the paper examines the basic laws based on which regional trade agreements are notified to the WTO and the evolution of these agreements in the period 1958-2013. The second part of the paper is devoted to the analysis of competition policy in regional trade agreements. In this part of the paper, to highlight the patterns of competition policy adopted under these agreements was analyzed by three case studies of competition policy in the EU, ASEAN and NAFTA. The three case studies have revealed that the three preferential trade agreements present regional competition policies with varying degrees of integration. The most complex form of competition policy is found in the European Union, because we are talking about a centralized model of competition policy. ASEAN presents a partially decentralized model, while NAFTA scrolls with a decentralized model of competition policy. The last part of the paper presents the characteristics of the four models of competition policy identified in the preferential trade agreements in force. It should be emphasized that if the initial preferential trade agreements have not put a great emphasis on the rules of competition policy, practice has shown the importance

  1. A Study on establishment of air preservation policy strategy in 21st century

    Energy Technology Data Exchange (ETDEWEB)

    Han, Hwa Jin; Kang, Kwang Kyu; Yoon, Jung Im [Korea Environment Institute, Seoul (Korea)

    1998-12-01

    For the air preservation and entire global environmental preservation in 21st century, it was implemented as a pre-work to maintain clean and clear air quality and to prepare a preventive air preservation policy. This study was focused on proposing the basic strategy of air preservation policy by deriving problems and evaluating actual results. 34 refs., 2 figs., 43 tabs.

  2. Education Policy in Poland: The Impact of PISA (and Other International Studies)

    Science.gov (United States)

    Bialecki, Ireneusz; Jakubowski, Maciej; Wisniewski, Jerzy

    2017-01-01

    The impact of the PISA study on Polish education policy has been significant, but probably different from any other country. Poland has not experienced the so-called "PISA shock," but its education system has been benefiting considerably from PISA. For experts and policy makers, it has been a useful and reliable instrument that has made…

  3. Big Business as a Policy Innovator in State School Reform: A Minnesota Case Study.

    Science.gov (United States)

    Mazzoni, Tim L.; Clugston, Richard M., Jr.

    1987-01-01

    The Minnesota Business Partnership (MBP) was studied as a policy innovator in state school reform (for kindergarten through grade 12) in relation to agenda setting, alternative formulation, and authoritative enactment. Focus is on the MBP's policy-making involvement during the 1985 state legislative session. Overall, the MBP's influence was…

  4. Young Children as Language Policy-Makers: Studies of Interaction in Preschools in Finland and Sweden

    Science.gov (United States)

    Boyd, Sally; Huss, Leena

    2017-01-01

    This special issue has as its focus the agency of young children in relation to language policy and practice in bi- and multilingual preschools in Finland and Sweden. Studies of language policy in practice in early childhood education and care (ECEC) in these two countries can be particularly relevant even to those in other contexts, because they…

  5. An Exploratory Study of Undergraduates' Attitudes toward Affirmative Action Policies for Asian Americans in College

    Science.gov (United States)

    Hartlep, Nicholas Daniel; Lowinger, Robert Jay

    2014-01-01

    This exploratory study examined white undergraduate students' (a) racial attitudes towards Asian Americans, (b) principled policy attitudes toward affirmative action, and (c) self-interest in relation to their support for college-based affirmative action policies for Asian Americans at a Midwestern university. A sample (n = 264, 28% male, 72%…

  6. Gender Equality in Media Content and Operations: Articulating Academic Studies and Policy--A Presentation

    Science.gov (United States)

    Lourenço, Mirta Edith

    2016-01-01

    In this article, Mirta Lourenço explains the prospects when higher education studies interface with UNESCO for policy change. The baseline is that education institutions' articulation with media organizations, media professionals, policy-makers, and civil society groups is essential to achieve gender equality in and through media.

  7. Migration Studies and Academic Research on International Migration Policies in Argentina

    Directory of Open Access Journals (Sweden)

    Eduardo Domenech

    2017-05-01

    Full Text Available This article approaches the historical development of the field of migratory studies in Argentina and makes a review of the academic production around the so - called "migratory policies." The systematization of these studies, historically placed on migration policies, aims to highlight some of the most significant contributions of the research during the last 30 years, to understand or explain various aspects and dimensions of the Argentinean migration policy. To achieve this, texts were selected that derived from empirical research that explicitly assume the migratory policies as the object of study, or whose themes and research problems adopt as a framework for discussion the policies and practices aimed at regulating migration and mobility in Argentina. The organization and presentation of these selected texts consider issues related to the interests and thematic concerns, disciplinary and analytical approaches, distinct periods, scales of analysis and sources of information.

  8. Path Dependence and Foreign Policy: A Case Study of United States Policy toward Lebanon

    National Research Council Canada - National Science Library

    Reyes, Raymond

    2004-01-01

    ... there. What has often been overlooked is the historical legacy of a tiny nation in the Levant: Lebanon. Many studies show Lebanon as a viable democracy prior to the start of its civil war in 1975...

  9. Energy Policy Act transportation rate study: Availability of data and studies

    Energy Technology Data Exchange (ETDEWEB)

    1993-10-13

    Pursuant to Section 1340(c) of the Energy Policy Act of 1992 (EPACT), this report presents the Secretary of Energy`s review of data collected by the Federal Government on rates for rail and pipeline transportation of domestic coal, oil, and gas for the years 1988 through 1997, and proposals to develop an adequate data base for each of the fuels, based on the data availability review. This report also presents the Energy Information Administration`s findings regarding the extent to which any Federal agency is studying the impacts of the Clean Air Act Amendments of 1990 (CAAA90) and other Federal policies on the transportation rates and distribution patterns of domestic coal, oil, and gas.

  10. Implementation of a Multichannel Serial Data Streaming Algorithm using the Xilinx Serial RapidIO Solution

    Science.gov (United States)

    Doxley, Charles A.

    2016-01-01

    In the current world of applications that use reconfigurable technology implemented on field programmable gate arrays (FPGAs), there is a need for flexible architectures that can grow as the systems evolve. A project has limited resources and a fixed set of requirements that development efforts are tasked to meet. Designers must develop robust solutions that practically meet the current customer demands and also have the ability to grow for future performance. This paper describes the development of a high speed serial data streaming algorithm that allows for transmission of multiple data channels over a single serial link. The technique has the ability to change to meet new applications developed for future design considerations. This approach uses the Xilinx Serial RapidIO LOGICORE Solution to implement a flexible infrastructure to meet the current project requirements with the ability to adapt future system designs.

  11. Diffusion thermopower of a serial double quantum dot

    International Nuclear Information System (INIS)

    Thierschmann, H; Henke, M; Knorr, J; Maier, L; Buhmann, H; Molenkamp, L W; Heyn, C; Hansen, W

    2013-01-01

    We have experimentally studied the diffusion thermopower of a serial double quantum dot, defined electrostatically in a GaAs/AlGaAs heterostructure. We present the thermopower stability diagram for a temperature difference ΔT = (20 ± 10) mK across the device and find a maximum thermovoltage signal of several μV in the vicinity of the triple points. Along a constant energy axis in this regime, the data show a characteristic pattern which is in agreement with Mott's relation and can be well understood within a model of sequential transport. (paper)

  12. Health policy and exercise: a brief BRFSS study and recommendations.

    Science.gov (United States)

    Larson, James S; Winn, Mylon

    2010-03-01

    The Behavioral Risk Factor Surveillance Survey is used to compare three predictors of self-rated health, specifically exercise, tobacco smoking, and a diagnosis of diabetes (a proxy for obesity). Exercise is found to be the best predictor, and the remainder of the article discusses the role of exercise in disease prevention and the all-important concept of exercise adherence. Government policy in the future needs to promote exercise adherence in a more rigorous way, because it is a key to both individual and societal health. Exercise habits need to be instilled from youth, and physical education requirements in school need to be re-established at all levels through high school. Adults also need encouragement with better neighborhood planning of exercise trails for walking and biking, as well as planned community activities to encourage fitness through one's lifetime. The article concludes with six recommendations for formal government action to encourage exercise adherence.

  13. Canadian solar export market study. Export policy recommendations

    Energy Technology Data Exchange (ETDEWEB)

    1983-11-01

    This report outlines policies and recommendations on the export of Canadian solar equipment and technology, with a view toward stimulating the domestic solar industry. The current picture is of an industry which is relatively small, operates in a competitive domestic market with low profit margins, and needs assistance in order to break into the world market. A number of recommendations are therefore made on the main thrust of industry and government solar export development activities. An export development program is described which includes a strategy of concentrating on a limited number of product lines, namely: low-temperature solar heating systems for recreational applications, integrated residential water heating systems, prepackaged commercial water heating systems, and industrial pre-heat systems. It is also recommended that this strategy be directed only at a limited number of target countries where the market justifies such activity. Market research, international cooperation agreements, promotional services, and proper export organization are also needed.

  14. Energy Information Data Base: serial titles

    International Nuclear Information System (INIS)

    1980-06-01

    The Department of Energy Technical Information Center (TIC) is responsible for creating bibliographic data bases that are used in the announcement and retrieval of publications dealing with all phases of energy. The TIC interactive information processing system makes use of a number of computerized authorities so that consistency can be maintained and indexes can be produced. One such authority is the Energy Information Data Base: Serial Titles. This authority contains the full and abbreviated journal title, country of publication, CODEN, and certain codes. This revision replaces previous revisions of this document

  15. Serials collection management in recessionary times

    CERN Document Server

    Lawson, Karen G

    2015-01-01

    Strategic planning, collaboration, continual stewardship, best practices, and re-engineering can provide librarians with a toolkit of innovative strategies that meets the worst of economic times with bold, persistent experimentation. This book covers the implications for libraries of a broad range of technological and economic challenges. These challenges include the fallout from the global economic crisis, the positioning of usage statistics, the advent of open access scholarship, database management, responding to budgetary constrictions and general access to serials. Taken as a whole, this

  16. Inverse Kinematics of a Serial Robot

    Directory of Open Access Journals (Sweden)

    Amici Cinzia

    2016-01-01

    Full Text Available This work describes a technique to treat the inverse kinematics of a serial manipulator. The inverse kinematics is obtained through the numerical inversion of the Jacobian matrix, that represents the equation of motion of the manipulator. The inversion is affected by numerical errors and, in different conditions, due to the numerical nature of the solver, it does not converge to a reasonable solution. Thus a soft computing approach is adopted to mix different traditional methods to obtain an increment of algorithmic convergence.

  17. Rapid serial visual presentation design for cognition

    CERN Document Server

    Spence, Robert

    2013-01-01

    A powerful new image presentation technique has evolved over the last twenty years, and its value demonstrated through its support of many and varied common tasks. Conceptually, Rapid Serial Visual Presentation (RSVP) is basically simple, exemplified in the physical world by the rapid riffling of the pages of a book in order to locate a known image. Advances in computation and graphics processing allow RSVP to be applied flexibly and effectively to a huge variety of common tasks such as window shopping, video fast-forward and rewind, TV channel selection and product browsing. At its heart is a

  18. CAR-T cells are serial killers.

    Science.gov (United States)

    Davenport, Alexander J; Jenkins, Misty R; Ritchie, David S; Prince, H Miles; Trapani, Joseph A; Kershaw, Michael H; Darcy, Phillip K; Neeson, Paul J

    2015-12-01

    Chimeric antigen receptor (CAR) T cells have enjoyed unprecedented clinical success against haematological malignancies in recent years. However, several aspects of CAR T cell biology remain unknown. We recently compared CAR and T cell receptor (TCR)-based killing in the same effector cell and showed that CAR T cells can not only efficiently kill single tumor targets, they can also kill multiple tumor targets in a sequential manner. Single and serial killing events were not sustained long term due to CAR down-regulation after 20 hours.

  19. Personality disorders, psychopathy and serial killers

    OpenAIRE

    Morana, Hilda C P; Stone, Michael H; Abdalla-Filho, Elias

    2006-01-01

    OBJETIVO: Apresentar as características básicas dos diversos transtornos específicos de personalidade, mas centrando-se no transtorno de personalidade anti-social, fazendo sua diferenciação com psicopatia. O estudo ainda se propõe a abordar a figura do serial killer, apontando a presença de aspectos psicopáticos no homicídio seriado. MÉTODO: Uma revisão bibliográfica foi feita no sentido de se abordar convergências e divergências entre diversos autores sobre um assunto tão polêmico, sobretudo...

  20. How do researchers influence decision-makers? Case studies of Mexican policies.

    Science.gov (United States)

    Trostle, J; Bronfman, M; Langer, A

    1999-06-01

    Though the problems translating or applying research in policy-making are legion, solutions are rare. As developing countries increase their capacities to develop effective local solutions to their health problems, they confront the research/policy dilemma. Yet few descriptive studies of research-policy links can be found from developing countries, and the relevance of European and North American models and data is questionable. We report the results of a descriptive study from Mexico of the relationship between health research and policy in four vertical programmes (AIDS, cholera, family planning, immunization). We interviewed 67 researchers and policy-makers from different institutions and levels of responsibility. We analyzed interviewee responses looking for factors that promoted or impeded exchanges between researchers and policy-makers. These were, in turn, divided into emphases on content, actors, process, and context. Many of the promoting factors resembled findings from studies in industrialized countries. Some important differences across the four programmes, which also distinguish them from industrialized country programmes, included extent of reliance on formal communication channels, role of the mass media in building social consensus or creating discord, levels of social consensus, role of foreign donors, and extent of support for biomedical versus social research. We recommend various ways to increase the impact of research on health policy-making in Mexico. Some of the largest challenges include the fact that researchers are but one of many interest groups, and research but one input among many equally legitimate elements to be considered by policy-makers. Another important challenge in Mexico is the relatively small role played by the public in policy-making. Further democratic changes in Mexico may be the most important incentive to increase the use of research in policy-making.

  1. Policy development and challenges of global mental health: a systematic review of published studies of national-level mental health policies.

    Science.gov (United States)

    Zhou, Wei; Yu, Yu; Yang, Mei; Chen, Lizhang; Xiao, Shuiyuan

    2018-05-18

    Mental health policy can be an essential and powerful tool to improve a population's mental health. However, around one third of countries do not possess a mental health policy, and there are large disparities in population coverage rates between high- and low-income countries. The goal of this study is to identify the transition and implementation challenges of mental health policies in both high-income countries (HICs) as well as middle- and low-income countries (MLICs). PubMed, Cochrane Library and Campbell Library were searched from inception to 31 December 2017, for studies on implemented mental health policies at the national level. Abstracts and the main texts of papers were double screened, and extracted data were analysed through thematic synthesis. A total of 93 papers were included in this study, covering 24 HICs, 28 MLICs and 5 regions. Studies on mental health policies, especially those of MLICs, kept increasing, but MLICs were still underrepresented in terms of publication quantity and study frequency. Based on the included studies, nine policy domains were summarized: service organizing, service provision, service quality, human resources, legislation and human rights, advocacy, administration, surveillance and research, and financing and budgeting. HICs incrementally enriched their policy content in all domains over centuries of development; following HICs' experience, mental health policies in MLICs have boomed since the 1990s and quickly extended to all domains. Implementation problems in HICs were mainly related to service organizing and service provision; for MLICs, more severe implementation problems converged on financing and budgeting, administration and human resources. Mental health policy developments in both HICs and MLICs present a process of diversification and enrichment. In terms of implementation, MLICs are faced with more and greater challenges than HICs, especially in funding, human resources and administration. Therefore, future

  2. Use of Comparative Case Study Methodology for US Public Health Policy Analysis: A Review.

    Science.gov (United States)

    Dinour, Lauren M; Kwan, Amy; Freudenberg, Nicholas

    There is growing recognition that policies influence population health, highlighting the need for evidence to inform future policy development and reform. This review describes how comparative case study methodology has been applied to public health policy research and discusses the methodology's potential to contribute to this evidence. English-language, peer-reviewed articles published between 1995 and 2012 were sought from 4 databases. Articles were included if they described comparative case studies addressing US public health policy. Two researchers independently assessed the 20 articles meeting review criteria. Case-related characteristics and research design tactics utilized to minimize threats to reliability and validity, such as the use of multiple sources of evidence and a case study protocol, were extracted from each article. Although comparative case study methodology has been used to analyze a range of public health policies at all stages and levels, articles reported an average use of only 3.65 (out of 10) research design tactics. By expanding the use of accepted research design tactics, public health policy researchers can contribute to expanding the evidence needed to advance health-promoting policies.

  3. Local government alcohol policy development: case studies in three New Zealand communities

    Science.gov (United States)

    Maclennan, Brett; Kypri, Kypros; Room, Robin; Langley, John

    2013-01-01

    Aims Local alcohol policies can be effective in reducing alcohol-related harm. The aim of this study was to examine local government responses to alcohol-related problems and identify factors influencing their development and adoption of alcohol policy. Designsettings and participants Case studies were used to examine local government responses to alcohol problems in three New Zealand communities: a rural town, a provincial city and a metropolitan city. Newspaper reports, local government documents and key informant interviews were used to collect data which were analysed using two conceptual frameworks: Kingdon's Streams model and the Stakeholder model of policy development. Measurements Key informant narratives were categorized according to the concepts of the Streams and Stakeholder models. Findings Kingdon's theoretical concepts associated with increased likelihood of policy change seemed to apply in the rural and metropolitan communities. The political environment in the provincial city, however, was not favourable to the adoption of alcohol restrictions. The Stakeholder model highlighted differences between the communities in terms of power over agenda-setting and conflict between politicians and bureaucrats over policy solutions to alcohol-related harm. These differences were reflected in the ratio of policies considered versus adopted in each location. Decisions on local alcohol policies lie ultimately with local politicians, although the policies that can be adopted by local government are restricted by central government legislation. Conclusions The adoption of policies and strategies to reduce alcohol-related harm may be better facilitated by an agenda-setting process where no ‘gate-keepers’ determine what is included into the agenda, and community mobilization efforts to create competitive local government elections around alcohol issues. Policy adoption would also be facilitated by more enabling central government legislation. PMID:23130762

  4. Status of infection control policies and organisation in European hospitals, 2001: the ARPAC study.

    NARCIS (Netherlands)

    Struelens, M.J.; Wagner, D.; Bruce, J.; MacKenzie, F.M.; Cookson, B.; Voss, A.; Broek, P.J.J.A. van den; Gould, I.

    2006-01-01

    Patient safety in hospital care depends on effective infection control (IC) programmes. The Antimicrobial Resistance Prevention and Control (ARPAC) study assessed the organisation, components and human resources of IC programmes in European hospitals. A questionnaire survey of policies and

  5. Energy efficient policy impact in India: case study of investment in industrial energy efficiency

    International Nuclear Information System (INIS)

    Yang, M.

    2006-01-01

    The objective of this paper is to identify the effectiveness of energy policy and capital investment in energy efficiency technologies in the industrial sector in India. Indian energy policies relating to industrial energy efficiency over the past 25 years are briefly reviewed, and a comparison study of these energy efficiency policies and strategies in India and China has been carried out. Interviews were conducted with a number of government policy-making institutions and a national industrial development bank. The accounts of 26 industrial enterprises which applied and used a loan of the Asian Development Bank were audited for data collection. Field-visits to seven industrial entrepreneurs were undertaken in a case study. Methodologies used in this study include documentation, cross-country reviews on energy policies, questionnaire design and distribution in the industrial sector, and on-site auditing of energy efficiency technologies. This paper concludes that current energy policies and strategies in India need further improvement to promote energy efficiency investment and energy efficiency technology development in the industrial sector. This paper will interest those policy makers and industrial entrepreneurs who are willing to finance energy efficiency projects and improve energy efficiency in the industrial sector. (author)

  6. Energy efficiency policy impact in India: case study of investment in industrial energy efficiency

    International Nuclear Information System (INIS)

    Yang Ming

    2006-01-01

    The objective of this paper is to identify the effectiveness of energy policy and capital investment in energy efficiency technologies in the industrial sector in India. Indian energy policies relating to industrial energy efficiency over the past 25 years are briefly reviewed, and a comparison study of these energy efficiency policies and strategies in India and China has been carried out. Interviews were conducted with a number of government policy-making institutions and a national industrial development bank. The accounts of 26 industrial enterprises which applied and used a loan of the Asian Development Bank were audited for data collection. Field-visits to seven industrial entrepreneurs were undertaken in a case study. Methodologies used in this study include documentation, cross-country reviews on energy policies, questionnaire design and distribution in the industrial sector, and on-site auditing of energy efficiency technologies. This paper concludes that current energy policies and strategies in India need further improvement to promote energy efficiency investment and energy efficiency technology development in the industrial sector. This paper will interest those policy makers and industrial entrepreneurs who are willing to finance energy efficiency projects and improve energy efficiency in the industrial sector

  7. Galileo - The Serial-Production AIT Challenge

    Science.gov (United States)

    Ragnit, Ulrike; Brunner, Otto

    2008-01-01

    The Galileo Project is one of the most demanding projects of ESA, being Europe's autarkic navigation system and a constellation composed of 30 satellites. This presentation points out the different phases of the project up to the full operational capability and the corresponding launch options with respect to launch vehicles as well as launch configurations. One of the biggest challenges is to set up a small serial 'production line' for the overall integration and test campaign of satellites. This production line demands an optimization of all relevant tasks, taking into account also backup and recovery actions. A comprehensive AIT concept is required, reflecting a tightly merged facility layout and work flow design. In addition a common data management system is needed to handle all spacecraft related documentation and to have a direct input-out flow for all activities, phases and positions at the same time. Process optimization is a well known field of engineering in all small high tech production lines, nevertheless serial production of satellites are still not the daily task in space business and therefore new concepts have to be put in place. Therefore, and in order to meet the satellites overall system optimization, a thorough interface between unit/subsystem manufacturing and satellite AIT must be realized to ensure a smooth flow and to avoid any process interruption, which would directly lead to a schedule impact.

  8. Serial position curves in free recall.

    Science.gov (United States)

    Laming, Donald

    2010-01-01

    The scenario for free recall set out in Laming (2009) is developed to provide models for the serial position curves from 5 selected sets of data, for final free recall, and for multitrial free recall. The 5 sets of data reflect the effects of rate of presentation, length of list, delay of recall, and suppression of rehearsal. Each model accommodates the serial position curve for first recalls (where those data are available) as well as that for total recalls. Both curves are fit with the same parameter values, as also (with 1 exception) are all of the conditions compared within each experiment. The distributions of numbers of recalls are also examined and shown to have variances increased above what would be expected if successive recalls were independent. This is taken to signify that, in those experiments in which rehearsals were not recorded, the retrieval of words for possible recall follows the same pattern that is observed following overt rehearsal, namely, that retrieval consists of runs of consecutive elements from memory. Finally, 2 sets of data are examined that the present approach cannot accommodate. It is argued that the problem with these data derives from an interaction between the patterns of (covert) rehearsal and the parameters of list presentation.

  9. Toward a Theoretical Framework for Studying Climate Change Policies: Insights from the Case Study of Singapore

    OpenAIRE

    Ai Sian Ng; May O. Lwin; Augustine Pang

    2017-01-01

    The world decided in December 2015 to take actions to reduce global warming. To contribute toward this goal, this research examines possible policy levers for inclusion in the climate change ratification plan. A case study of the measures taken by the Republic of Singapore, a low-lying 719.2 km2 island without natural resources in Asia, is conducted. Being vulnerable to climate change impact and yet having to balance her people’s needs and economic progress with limited resources, the measure...

  10. Uganda tax policy reforms: A case study of Uganda revenue authority URA

    OpenAIRE

    Kato, Simon Kagambirwe

    2014-01-01

    In this study I examined the implementation of tax policy reforms at Uganda Revenue Authority. In particular, I examined the impact of the tax policy reforms implemented since the restructuring of Uganda Revenue Authority in 2005. Although Uganda's taxation system is a vital area of study, it has not gotten enough attention from researchers. This is because, in the Ugandan and generally African developing countries context, taxation involves vital and, to a large ex...

  11. Integrating Financial Aid and Financial Policies: Case Studies from Five States. Changing Direction: Integrating Higher Education Financial Aid and Financing Policies.

    Science.gov (United States)

    Western Interstate Commission for Higher Education, Boulder, CO.

    This report is a collection of five state case studies comprising a major component of the first phase of the project, "Changing Direction: Integrating Higher Education Financial Aid and Financing Policies." The project explored state-level strategies to better align financing and financial aid policies and support more informed decision…

  12. Working memory capacity and controlled serial memory search.

    Science.gov (United States)

    Mızrak, Eda; Öztekin, Ilke

    2016-08-01

    The speed-accuracy trade-off (SAT) procedure was used to investigate the relationship between working memory capacity (WMC) and the dynamics of temporal order memory retrieval. High- and low-span participants (HSs, LSs) studied sequentially presented five-item lists, followed by two probes from the study list. Participants indicated the more recent probe. Overall, accuracy was higher for HSs compared to LSs. Crucially, in contrast to previous investigations that observed no impact of WMC on speed of access to item information in memory (e.g., Öztekin & McElree, 2010), recovery of temporal order memory was slower for LSs. While accessing an item's representation in memory can be direct, recovery of relational information such as temporal order information requires a more controlled serial memory search. Collectively, these data indicate that WMC effects are particularly prominent during high demands of cognitive control, such as serial search operations necessary to access temporal order information from memory. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. In vivo serial sampling of epididymal sperm in mice.

    Science.gov (United States)

    Del Val, Gonzalo Moreno; Robledano, Patricia Muñoz

    2013-07-01

    This study was undertaken to refine the techniques of in vivo collection of sperm in the mouse. The principal objective was to offer a viable, safe and reliable method for serial collection of in vivo epididimary sperm through the direct puncture of the epididymis. Six C57Bl/6J males were subjected to the whole experiment. First we obtain a sperm sample of the right epididymis, and perform a vasectomy on the left side. This sample was used in an in vitro fertilization (IVF) experiment while the males were individually housed for 10 days to let them recover from the surgery, and then their fertility was tested with natural matings until we obtained a litter of each one. After that, the animals were subjected another time to the same process (sampling, recover and natural mating). The results of these experiments were a fertilization average value of 56.7%, and that all the males had a litter in the first month after the natural matings. This study documented the feasibility of the epididimary puncture technique to in vivo serial sampling of sperm in the mouse.

  14. Forgiveness and Suicidal Behavior: Cynicism and Psychache as Serial Mediators.

    Science.gov (United States)

    Dangel, Trever J; Webb, Jon R; Hirsch, Jameson K

    2018-02-17

    Research is burgeoning regarding the beneficial association of forgiveness with numerous health-related outcomes; however, its particular relationship to suicidal behavior has received relatively little attention. Both cynicism and psychache, or agonizing psychological pain, have displayed deleterious associations with suicidal behavior, but have rarely been incorporated into more comprehensive models of suicidal behavior. Consistent with the recent development of a theoretical model regarding the forgiveness-suicidal behavior association, the present study utilized an undergraduate sample of college students (N = 312) to test a mediation-based model of the cross-sectional association of forgiveness with suicidal behavior, as serially mediated by cynicism and psychache. Dispositional forgiveness of self and forgiveness of uncontrollable situations were each indirectly associated with less suicidal behavior via less psychache. Also, dispositional forgiveness of others was indirectly associated with less suicidal behavior via less cynicism and less psychache, in a serial fashion. The present results are consistent with the extent literature on the forgiveness-suicidal behavior association, cynicism, and psychache, and pending future studies, may be utilized to inform further treatment efforts for individuals at a high risk of attempting suicide.

  15. Policy Implementation Study on Spatial Planning for Environmental Conflict (Study Location: Rembang Regency)

    Science.gov (United States)

    Kusyuniadi, Indraya

    2018-02-01

    This study aims to see the impact and benefits as an outcome of a policy, where this policy is in the form of spatial planning (Regional Planning). As known RTRW is a product that can be regarded as "the book of development" in every region both in the provincial and regional levels. One of them is as a decision tool for investors (investors) in increasing local development investment, spatial planning (RTRW) is also expected to maintain the environment, in order to support the sustainability of regional development. In reality, there are still many conflicts of interest in the implementation process of regional development, especially between economic and environmental interests. Often the interests of regional sustainability are placed at a lower level (less priority) than investment / economy. Land conversion that is inconsistent with district / city spatial planning RTRW is relatively still occurring, especially for economic purposes. Lack of policy called spatial plan in this case RTRW Province and Regency in responding to existing condition in field. How can a product that is said to be "Scripture" a regional planning is powerless in fulfilling the space for investment in the form of industry, commercial, housing and so forth. There are several results that can be concluded in this study. Basically, the importance of the environment at least can be used as the basis or priority of the main decision makers above economic interests and other politic interests. The current Spatial Plan / RTRW document still holds a big question whether at the time of compilation it follows the norms and rules in a plan (data accuracy, through input process from the community).

  16. Policy Implementation Study on Spatial Planning for Environmental Conflict (Study Location: Rembang Regency

    Directory of Open Access Journals (Sweden)

    Kusyuniadi Indraya

    2018-01-01

    Full Text Available This study aims to see the impact and benefits as an outcome of a policy, where this policy is in the form of spatial planning (Regional Planning. As known RTRW is a product that can be regarded as "the book of development" in every region both in the provincial and regional levels. One of them is as a decision tool for investors (investors in increasing local development investment, spatial planning (RTRW is also expected to maintain the environment, in order to support the sustainability of regional development. In reality, there are still many conflicts of interest in the implementation process of regional development, especially between economic and environmental interests. Often the interests of regional sustainability are placed at a lower level (less priority than investment / economy. Land conversion that is inconsistent with district / city spatial planning RTRW is relatively still occurring, especially for economic purposes. Lack of policy called spatial plan in this case RTRW Province and Regency in responding to existing condition in field. How can a product that is said to be "Scripture" a regional planning is powerless in fulfilling the space for investment in the form of industry, commercial, housing and so forth. There are several results that can be concluded in this study. Basically, the importance of the environment at least can be used as the basis or priority of the main decision makers above economic interests and other politic interests. The current Spatial Plan / RTRW document still holds a big question whether at the time of compilation it follows the norms and rules in a plan (data accuracy, through input process from the community.

  17. CMOS serial link for fully duplexed data communication

    Science.gov (United States)

    Lee, Kyeongho; Kim, Sungjoon; Ahn, Gijung; Jeong, Deog-Kyoon

    1995-04-01

    This paper describes a CMOS serial link allowing fully duplexed 500 Mbaud serial data communication. The CMOS serial link is a robust and low-cost solution to high data rate requirements. A central charge pump PLL for generating multiphase clocks for oversampling is shared by several serial link channels. Fully duplexed serial data communication is realized in the bidirectional bridge by separating incoming data from the mixed signal on the cable end. The digital PLL accomplishes process-independent data recovery by using a low-ratio oversampling, a majority voting, and a parallel data recovery scheme. Mostly, digital approach could extend its bandwidth further with scaled CMOS technology. A single channel serial link and a charge pump PLL are integrated in a test chip using 1.2 micron CMOS process technology. The test chip confirms upto 500 Mbaud unidirectional mode operation and 320 Mbaud fully duplexed mode operation with pseudo random data patterns.

  18. Development of a conceptual policy framework for advanced practice nursing: an ethnographic study.

    Science.gov (United States)

    Schober, Madrean M; Gerrish, Kate; McDonnell, Ann

    2016-06-01

    To report on a study examining policy development for advanced practice nursing from intent of policy to realization in practice. Inclusion of advanced practice nursing roles in the healthcare workforce is a worldwide trend. Optimal advanced nursing practice requires supportive policies. Little is known about how policy is developed and implemented. Ethnography using an instrumental case study approach was selected to give an in-depth understanding of the experiences of one country (Singapore) to contribute to insight into development elsewhere. The four-phase study was conducted from 2008-2012 and included document analysis (n = 47), interviews with key policy decision makers (n = 12), interviews with nursing managers and medical directors (n = 11), interviews and participant observation with advanced practice nurses (n = 15). Key policymakers in positions of authority were able to promote policy development. However, this was characterized by lack of strategic planning for implementation. A vague understanding by nursing managers and medical directors of policies, the role and its position in the healthcare workforce led to indecision and uncertainty in execution. Advanced practice nurses developed their role based on theory acquired in their academic programme but were unsure what role to assume in practice. Lack of clear guidelines led to unanticipated difficulties for institutions and healthcare systems. Strategic planning could facilitate integration of advanced practice nurses into the healthcare workforce. A Conceptual Policy Framework is proposed as a guide for a coordinated approach to policy development and implementation for advanced practice nursing. © 2016 John Wiley & Sons Ltd.

  19. CAMAC serial highway interface for the LSI-11

    International Nuclear Information System (INIS)

    Lau, N.H.

    1980-01-01

    A CAMAC Serial Highway Interface has been designed for the Local Control and Instrumentation System of the Mirror Fusion Test Facility. There are over 50 distinguishable systems in the facility, each of which consists of the LSI-11 computer, fiber optic communication links, and the CAMAC system. The LSI-11 computer includes a 32k memory, serial modem interface and the CAMAC Serial Highway Interface

  20. The utilization of forensic science and criminal profiling for capturing serial killers.

    Science.gov (United States)

    White, John H; Lester, David; Gentile, Matthew; Rosenbleeth, Juliana

    2011-06-15

    Movies and nightly television shows appear to emphasize highly efficient regimens in forensic science and criminal investigative analysis (profiling) that result in capturing serial killers and other perpetrators of homicide. Although some of the shows are apocryphal and unrealistic, they reflect major advancements that have been made in the fields of forensic science and criminal psychology during the past two decades that have helped police capture serial killers. Some of the advancements are outlined in this paper. In a study of 200 serial killers, we examined the variables that led to police focusing their attention on specific suspects. We developed 12 categories that describe how serial killers come to the attention of the police. The results of the present study indicate that most serial killers are captured as a result of citizens and surviving victims contributing information that resulted in police investigations that led to an arrest. The role of forensic science appears to be important in convicting the perpetrator, but not necessarily in identifying the perpetrator. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  1. Stakeholders’ Views on Factors Influencing Nutrition Policy: a Qualitative Study Across Ten European Countries

    Directory of Open Access Journals (Sweden)

    Jeruszka-Bielak Marta

    2015-12-01

    Full Text Available The objective was to identify the main factors influencing micronutrient policies in the opinion of policy actors in ten European countries. Study was carried out during Jan-Nov 2010 in European countries: the Czech Republic, Denmark, England, Germany, Greece, Italy, the Netherlands, Norway, Poland and Spain. Semi-structured qualitative interviews were conducted with representatives of stakeholders involved in the vitamin D, folate and iodine policy making process. Fifty eight key informants representing mainly scientific advisory bodies (n=24 and governmental organisations (n=19 participated in the study. The remaining interviewees represented non-governmental organisations (n=6, industry (n=4 or were independent academic or health professional experts (n=5. Data were analysed by theoretical interpretative thematic analysis. Insights from interviewees on the development of micronutrient policies were grouped using the Public Health Nutrition Policy-making model. The main factors influencing the micronutrient policies were: systematic monitoring of nutrition and health, causal relationships between consumers’ diet-related behaviours and health outcomes, scientific recommendations from national bodies (Science area; scientific recommendations from international authorities and experiences of other countries, EU legislation, cultural factors (Wider context and political environment, national capacity to deal with the problem, national legislation, economics, stakeholder engagement, relationships between stakeholders (Policy and institutions area. The spectrum and weight of the factors influencing nutritional policy depends on nutrient, country and degree of its “advanced status” within nutrition policy, political environment, culture and socio-economic conditions as well as the point of view (who is expressing the opinion.

  2. Automated detection of multiple sclerosis lesions in serial brain MRI

    International Nuclear Information System (INIS)

    Llado, Xavier; Ganiler, Onur; Oliver, Arnau; Marti, Robert; Freixenet, Jordi; Valls, Laia; Vilanova, Joan C.; Ramio-Torrenta, Lluis; Rovira, Alex

    2012-01-01

    Multiple sclerosis (MS) is a serious disease typically occurring in the brain whose diagnosis and efficacy of treatment monitoring are vital. Magnetic resonance imaging (MRI) is frequently used in serial brain imaging due to the rich and detailed information provided. Time-series analysis of images is widely used for MS diagnosis and patient follow-up. However, conventional manual methods are time-consuming, subjective, and error-prone. Thus, the development of automated techniques for the detection and quantification of MS lesions is a major challenge. This paper presents an up-to-date review of the approaches which deal with the time-series analysis of brain MRI for detecting active MS lesions and quantifying lesion load change. We provide a comprehensive reference source for researchers in which several approaches to change detection and quantification of MS lesions are investigated and classified. We also analyze the results provided by the approaches, discuss open problems, and point out possible future trends. Lesion detection approaches are required for the detection of static lesions and for diagnostic purposes, while either quantification of detected lesions or change detection algorithms are needed to follow up MS patients. However, there is not yet a single approach that can emerge as a standard for the clinical practice, automatically providing an accurate MS lesion evolution quantification. Future trends will focus on combining the lesion detection in single studies with the analysis of the change detection in serial MRI. (orig.)

  3. Serial album validation for promotion of infant body weight control

    Directory of Open Access Journals (Sweden)

    Nathalia Costa Gonzaga Saraiva

    2018-05-01

    Full Text Available ABSTRACT Objective: to validate the content and appearance of a serial album for children aged from 7 to 10 years addressing the topic of prevention and control of body weight. Method: methodological study with descriptive nature. The validation process was attended by 33 specialists in educational technologies and/or in excess of infantile weight. The agreement index of 80% was the minimum considered to guarantee the validation of the material. Results: most of the specialists had a doctoral degree and a graduate degree in nursing. Regarding content, illustrations, layout and relevance, all items were validated and 69.7% of the experts considered the album as great. The overall agreement validation index for the educational technology was 0.88. Only the script-sheet 3 did not reach the cutoff point of the content validation index. Changes were made to the material, such as title change, inclusion of the school context and insertion of nutritionist and physical educator in the story narrated in the album. Conclusion: the proposed serial album was considered valid by experts regarding content and appearance, suggesting that this technology has the potential to contribute in health education by promoting healthy weight in the age group of 7 to 10 years.

  4. Automated detection of multiple sclerosis lesions in serial brain MRI

    Energy Technology Data Exchange (ETDEWEB)

    Llado, Xavier; Ganiler, Onur; Oliver, Arnau; Marti, Robert; Freixenet, Jordi [University of Girona, Computer Vision and Robotics Group, Girona (Spain); Valls, Laia [Dr. Josep Trueta University Hospital, Department of Radiology, Girona (Spain); Vilanova, Joan C. [Girona Magnetic Resonance Center, Girona (Spain); Ramio-Torrenta, Lluis [Dr. Josep Trueta University Hospital, Institut d' Investigacio Biomedica de Girona, Multiple Sclerosis and Neuroimmunology Unit, Girona (Spain); Rovira, Alex [Vall d' Hebron University Hospital, Magnetic Resonance Unit, Department of Radiology, Barcelona (Spain)

    2012-08-15

    Multiple sclerosis (MS) is a serious disease typically occurring in the brain whose diagnosis and efficacy of treatment monitoring are vital. Magnetic resonance imaging (MRI) is frequently used in serial brain imaging due to the rich and detailed information provided. Time-series analysis of images is widely used for MS diagnosis and patient follow-up. However, conventional manual methods are time-consuming, subjective, and error-prone. Thus, the development of automated techniques for the detection and quantification of MS lesions is a major challenge. This paper presents an up-to-date review of the approaches which deal with the time-series analysis of brain MRI for detecting active MS lesions and quantifying lesion load change. We provide a comprehensive reference source for researchers in which several approaches to change detection and quantification of MS lesions are investigated and classified. We also analyze the results provided by the approaches, discuss open problems, and point out possible future trends. Lesion detection approaches are required for the detection of static lesions and for diagnostic purposes, while either quantification of detected lesions or change detection algorithms are needed to follow up MS patients. However, there is not yet a single approach that can emerge as a standard for the clinical practice, automatically providing an accurate MS lesion evolution quantification. Future trends will focus on combining the lesion detection in single studies with the analysis of the change detection in serial MRI. (orig.)

  5. Improved Software to Browse the Serial Medical Images for Learning.

    Science.gov (United States)

    Kwon, Koojoo; Chung, Min Suk; Park, Jin Seo; Shin, Byeong Seok; Chung, Beom Sun

    2017-07-01

    The thousands of serial images used for medical pedagogy cannot be included in a printed book; they also cannot be efficiently handled by ordinary image viewer software. The purpose of this study was to provide browsing software to grasp serial medical images efficiently. The primary function of the newly programmed software was to select images using 3 types of interfaces: buttons or a horizontal scroll bar, a vertical scroll bar, and a checkbox. The secondary function was to show the names of the structures that had been outlined on the images. To confirm the functions of the software, 3 different types of image data of cadavers (sectioned and outlined images, volume models of the stomach, and photos of the dissected knees) were inputted. The browsing software was downloadable for free from the homepage (anatomy.co.kr) and available off-line. The data sets provided could be replaced by any developers for their educational achievements. We anticipate that the software will contribute to medical education by allowing users to browse a variety of images. © 2017 The Korean Academy of Medical Sciences.

  6. Volume imaging NDE and serial sectioning of carbon fiber composites

    Science.gov (United States)

    Hakim, Issa; Schumacher, David; Sundar, Veeraraghavan; Donaldson, Steven; Creuz, Aline; Schneider, Rainer; Keller, Juergen; Browning, Charles; May, Daniel; Ras, Mohamad Abo; Meyendorf, Norbert

    2018-04-01

    A composite material is a combination of two or more materials with very different mechanical, thermal and electrical properties. The various forms of composite materials, due to their high material properties, are widely used as structural materials in the aviation, space, marine, automobile, and sports industries. However, some defects like voids, delamination, or inhomogeneous fiber distribution that form during the fabricating processes of composites can seriously affect the mechanical properties of the composite material. In this study, several imaging NDE techniques such as: thermography, high frequency eddy current, ultrasonic, x-ray radiography, x-ray laminography, and high resolution x-ray CT were conducted to characterize the microstructure of carbon fiber composites. Then, a 3D analysis was implemented by the destructive technique of serial sectioning for the same sample tested by the NDE methods. To better analyze the results of this work and extract a clear volume image for all features and defects contained in the composite material, an intensive comparison was conducted among hundreds of 3D-NDE and multi serial sections' scan images showing the microstructure variation.

  7. Nonlinear Process Fault Diagnosis Based on Serial Principal Component Analysis.

    Science.gov (United States)

    Deng, Xiaogang; Tian, Xuemin; Chen, Sheng; Harris, Chris J

    2018-03-01

    Many industrial processes contain both linear and nonlinear parts, and kernel principal component analysis (KPCA), widely used in nonlinear process monitoring, may not offer the most effective means for dealing with these nonlinear processes. This paper proposes a new hybrid linear-nonlinear statistical modeling approach for nonlinear process monitoring by closely integrating linear principal component analysis (PCA) and nonlinear KPCA using a serial model structure, which we refer to as serial PCA (SPCA). Specifically, PCA is first applied to extract PCs as linear features, and to decompose the data into the PC subspace and residual subspace (RS). Then, KPCA is performed in the RS to extract the nonlinear PCs as nonlinear features. Two monitoring statistics are constructed for fault detection, based on both the linear and nonlinear features extracted by the proposed SPCA. To effectively perform fault identification after a fault is detected, an SPCA similarity factor method is built for fault recognition, which fuses both the linear and nonlinear features. Unlike PCA and KPCA, the proposed method takes into account both linear and nonlinear PCs simultaneously, and therefore, it can better exploit the underlying process's structure to enhance fault diagnosis performance. Two case studies involving a simulated nonlinear process and the benchmark Tennessee Eastman process demonstrate that the proposed SPCA approach is more effective than the existing state-of-the-art approach based on KPCA alone, in terms of nonlinear process fault detection and identification.

  8. Serial Contradictions. The Italian Debate on Tv Series

    Directory of Open Access Journals (Sweden)

    Daniela Cardini

    2016-06-01

    Full Text Available In the last decade the academic debate on television seriality has become lively and often quite animated, in the US as well as in Italy. The traditional hierarchic relation between cinema and television is clearly represented by the form of the most recent tv drama, whose boundaries are more and more difficult to locate. The main questions at stake seem to be the so-called “cinematic television” (Mills, 2013; Jaramillo, 2013, the umbrella definition of “quality tv” (McCabe and Akass, 2007 and its relation with the broadest concept of “complex tv” (Mittell, 2009, 2015. The essay will take into consideration these oxymorons, which are deeply rooted in the Italian tv series debate, with the aim of considering both their risks and their opportunities. A great variety of texts are grouped under the “tv series” label, but they are very different as far as content, production values and audience reactions are concerned. The academic discourse, however, only recently has tried to identify the differences between longstanding mainstream shows (such as, for instance, Grey’s Anatomy or CSI and some more recent, and supposedly “cinematic” series like True Detective or Fargo. Together with the analysis of the oxymoric nature of recent television seriality, the essay will explore the need to historicising what is proving to be one of the most dense and fruitful domains of recent television studies.

  9. Malignant sex and aggression: an overview of serial sexual homicide.

    Science.gov (United States)

    Myers, W C; Reccoppa, L; Burton, K; McElroy, R

    1993-01-01

    Serial murderers have attracted considerable attention in the popular press and criminal justice field, but scientific literature about these individuals is limited. This article provides an overview, from a psychiatric perspective, of serial sexual homicide, one type of serial killing. Characteristics of this type of murder and of these offenders are discussed. Defining qualities and diagnoses applicable to serial sexual killers are reviewed. Various etiologic theories are discussed, with emphasis on the role of fantasy and psychodynamic explanations. Governmental agencies involved in combating this type of crime, along with the role of mental health professionals in criminal profiling, are presented. Finally, the authors explore the reaction of society to this phenomenon.

  10. Accounting for health in climate change policies: a case study of Fiji.

    Science.gov (United States)

    Morrow, Georgina; Bowen, Kathryn

    2014-01-01

    Climate change is expected to affect the health of most populations in the coming decades, having the greatest impact on the poorest and most disadvantaged people in the world. The Pacific islands, including Fiji, are particularly vulnerable to the effects of climate change. The three major health impacts of climate change in Fiji explored in this study were dengue fever, diarrhoeal disease, and malnutrition, as they each pose a significant threat to human health. The aim of this study was to investigate to what extent the Fiji National Climate Change Policy, and a selection of relevant sectoral policies, account for these human health effects of climate change. The study employed a three-pronged policy analysis to evaluate: 1) the content of the Fijian National Climate Change Policy and to what extent health was incorporated within this; 2) the context within which the policy was developed; 3) the relevant processes; and 4) the actors involved. A selection of relevant sectoral policies were also analysed to assess the extent to which these included climate change and health considerations. The policy analysis showed that these three health impacts of climate change were only considered to a minor extent, and often indirectly, in both the Fiji National Climate Change Policy and the corresponding National Climate Change Adaptation Strategy, as well as the Public Health Act. Furthermore, supporting documents in relevant sectors including water and agriculture made no mention of climate change and health impacts. The projected health impacts of climate change should be considered as part of reviewing the Fiji National Climate Change Policy and National Climate Change Adaptation Strategy, and the Public Health Act. In the interest of public health, this should include strategies for combating dengue fever, malnutrition, and water-borne disease. Related sectoral policies in water and agriculture should also be revised to consider climate change and its impact on human

  11. Accounting for health in climate change policies: a case study of Fiji

    Directory of Open Access Journals (Sweden)

    Georgina Morrow

    2014-05-01

    Full Text Available Background: Climate change is expected to affect the health of most populations in the coming decades, having the greatest impact on the poorest and most disadvantaged people in the world. The Pacific islands, including Fiji, are particularly vulnerable to the effects of climate change. Objective: The three major health impacts of climate change in Fiji explored in this study were dengue fever, diarrhoeal disease, and malnutrition, as they each pose a significant threat to human health. The aim of this study was to investigate to what extent the Fiji National Climate Change Policy, and a selection of relevant sectoral policies, account for these human health effects of climate change. Design: The study employed a three-pronged policy analysis to evaluate: 1 the content of the Fijian National Climate Change Policy and to what extent health was incorporated within this; 2 the context within which the policy was developed; 3 the relevant processes; and 4 the actors involved. A selection of relevant sectoral policies were also analysed to assess the extent to which these included climate change and health considerations. Results: The policy analysis showed that these three health impacts of climate change were only considered to a minor extent, and often indirectly, in both the Fiji National Climate Change Policy and the corresponding National Climate Change Adaptation Strategy, as well as the Public Health Act. Furthermore, supporting documents in relevant sectors including water and agriculture made no mention of climate change and health impacts. Conclusions: The projected health impacts of climate change should be considered as part of reviewing the Fiji National Climate Change Policy and National Climate Change Adaptation Strategy, and the Public Health Act. In the interest of public health, this should include strategies for combating dengue fever, malnutrition, and water-borne disease. Related sectoral policies in water and agriculture should

  12. Bringing the Low-Carbon Agenda to China: A Study in Transnational Policy Diffusion

    Directory of Open Access Journals (Sweden)

    Andreas Hofem

    2013-01-01

    Full Text Available This study traces the transnational interactions that contributed to introducing the low-carbon economy agenda into Chinese policymaking. A microprocessual two-level analysis (outside-in as well as inside-access is employed to analyse transnational and domestic exchanges. The study provides evidence that low-carbon agenda-setting – introduced by transnational actors, backed by foreign funding, promoted by policy entrepreneurs from domestic research institutes, propelled by top-level attention, but only gradually and cautiously adopted by the government bureaucracy – can be considered a case of effective transnational diffusion based on converging perceptions of novel policy challenges and options. Opinion leaders and policy-brokers from the government-linked scientific community functioned as effective access points to the Chinese government’s policy agenda.

  13. Woody Allen, serial schlemiel ?

    Directory of Open Access Journals (Sweden)

    Frédérique Brisset

    2011-04-01

    Full Text Available Woody Allen a développé au fil des années une persona cinématographique de schlemiel new-yorkais aisément reconnaissable par le spectateur. Elle marque nombre de ses films, qu’il y apparaisse en tant qu’acteur ou y dirige des substituts comédiens comme déclinaisons de lui-même. Si cette figure prototypique est le fondement de la sérialité dans sa filmographie, il est des traits stylistiques qui en portent trace tout au long de son œuvre : la récurrence annuelle de ses réalisations, la signature formelle symbolisée par ses génériques à la typographie singulière, le rythme de ses dialogues ponctués d’interjections et l’usage de l’autocitation sont autant de procédés qui marquent son cinéma d’un sceau très personnel. Ils fonctionnent comme des clins d’œil au spectateur qui reçoit dès lors LE Woody Allen millésimé comme une invitation à retrouver son microcosme. Ainsi la sérialité se pose comme à la fois initiale et conséquentielle de son système filmique, processus de création unique dans le cinéma américain.Woody Allen has long constructed a cinematographic persona of schlemiel New- Yorker that the audience can easily identify. It impacts most of his films, whether he stars in them or directs “substitute” actors to impersonate his character. If this prototypical figure is the basis of seriality in his cinematography, serial stylistic features can also be found all along his career: the annual recurrence of his productions, the formal signature symbolised by the typography of his singular credit titles, his rhythmical interjection-punctuated dialogues and the use of self-quotation imprint a very personal seal upon his movies. They all work as a recognition signals for the audience who thus receive THE Woody Allen vintage as an invitation to re-enter his microcosm. Seriality is then both initial and consequential to his cinematographic system, a unique creative process in American film history.

  14. Public policy influence on renewable energy investments—A panel data study across OECD countries

    International Nuclear Information System (INIS)

    Polzin, Friedemann; Migendt, Michael; Täube, Florian A.; Flotow, Paschen von

    2015-01-01

    This paper examines the impact of public policy measures on renewable energy (RE) investments in electricity-generating capacity made by institutional investors. Using a novel combination of datasets and a longitudinal research design, we investigate the influence of different policy measures in a sample of OECD countries to suggest an effective policy mix which could tackle failures in the market for clean energy. The results call for technology-specific policies which take into account actual market conditions and technology maturity. To improve the conditions for institutional investments, advisable policy instruments include economic and fiscal incentives such as feed-in tariffs (FIT), especially for less mature technologies. Additionally, market-based instruments such as greenhouse gas (GHG) emission trading systems for mature technologies should be included. These policy measures directly impact the risk and return structure of RE projects. Supplementing these with regulatory measures such as codes and standards (e.g. RPS) and long-term strategic planning could further strengthen the context for RE investments. - Highlights: • Panel data study on the effectiveness of policies to induce RE investments. • Novel combination of datasets (BNEF/IEA) in solar, wind and biomass sectors. • FIT proves to be more effective than subsidies for less mature technologies. • RPS and tradable permit systems seem more effective for mature technologies. • A long-term strategic planning framework is useful to attract institutional investors

  15. Grenada School Nutrition Study: Evidence to Inform Policy

    International Development Research Centre (IDRC) Digital Library (Canada)

    Grenada School Nutrition Study: Evidence to Inform ... research focusing on the main risk factors for NCDs: tobacco use, unhealthy diet, alcohol misuse, and physical inactivity. ... study predicts that non-communicable diseases associated.

  16. Policy Options for Private Forest Owners in Western Balkans: A Qualitative Study

    OpenAIRE

    Mersudin AVDIBEGOVIĆ; Dragan NONIĆ; Stjepan POSAVEC; Nenad PETROVIĆ; Bruno MARIĆ; Vojislav MILIJIĆ; Silvija KRAJTER; Florin IORAS; Ioan Vasile ABRUDAN

    2010-01-01

    Private forest owners start to play an important role in Western Balkans’ forestry and they are essential to the successful implementation of environmental policies. Little is known about how forest policy can support private forest owners in these countries and therefore this study was conducted though a qualitative method, based on personal interviews with representatives of 54 stakeholders that include state forest authorities and administration, private forest owners associations, forest ...

  17. Open Access Policies of Research Funders: The Case Study of the Austrian Science Fund (FWF)

    OpenAIRE

    Tonto, Yaşar; Doğan, Güleda; Al, Umut; Madran, Orçun

    2015-01-01

    The Austrian Science Fund (FWF) is the main funder for basic research in Austria. FWF has been instrumental in promoting Open Access in Austria and elsewhere and possesses a strong Open Access policy for the research it funds. This case study presents FWF as a good practice of an effective funder policy on account of its comprehensive strategy and multi-faceted approach for implementing and supporting it.

  18. Impaired Processing of Serial Order Determines Working Memory Impairments in Alzheimer's Disease.

    Science.gov (United States)

    De Belder, Maya; Santens, Patrick; Sieben, Anne; Fias, Wim

    2017-01-01

    Working memory (WM) problems are commonly observed in Alzheimer's disease (AD), but the affected mechanisms leading to impaired WM are still insufficiently understood. The ability to efficiently process serial order in WM has been demonstrated to be fundamental to fluent daily life functioning. The decreased capability to mentally process serial position in WM has been put forward as the underlying explanation for generally compromised WM performance. Determine which mechanisms, such as order processing, are responsible for deficient WM functioning in AD. A group of AD patients (n = 32) and their partners (n = 25), assigned to the control group, were submitted to an extensive battery of neuropsychological and experimental tasks, assessing general cognitive state and functioning of several aspects related to serial order WM. The results revealed an impaired ability to bind item information to serial position within WM in AD patients compared to controls. It was additionally observed that AD patients experienced specific difficulties with directing spatial attention when searching for item information stored in WM. The processing of serial order and the allocation of attentional resources are both disrupted, explaining the generally reduced WM functioning in AD patients. Further studies should now clarify whether this observation could explain disease-related problems for other cognitive functions such as verbal expression, auditory comprehension, or planning.

  19. Motor cortical encoding of serial order in a context-recall task.

    Science.gov (United States)

    Carpenter, A F; Georgopoulos, A P; Pellizzer, G

    1999-03-12

    The neural encoding of serial order was studied in the motor cortex of monkeys performing a context-recall memory scanning task. Up to five visual stimuli were presented successively on a circle (list presentation phase), and then one of them (test stimulus) changed color; the monkeys had to make a single motor response toward the stimulus that immediately followed the test stimulus in the list. Correct performance in this task depends on memorization of the serial order of the stimuli during their presentation. It was found that changes in neural activity during the list presentation phase reflected the serial order of the stimuli; the effect on cell activity of the serial order of stimuli during their presentation was at least as strong as the effect of motor direction on cell activity during the execution of the motor response. This establishes the serial order of stimuli in a motor task as an important determinant of motor cortical activity during stimulus presentation and in the absence of changes in peripheral motor events, in contrast to the commonly held view of the motor cortex as just an "upper motor neuron."

  20. Effect of parental family history of Alzheimer's disease on serial position profiles.

    Science.gov (United States)

    La Rue, Asenath; Hermann, Bruce; Jones, Jana E; Johnson, Sterling; Asthana, Sanjay; Sager, Mark A

    2008-07-01

    An exaggerated recency effect (ie, disproportionate recall of last-presented items) has been consistently observed in the word list learning of patients with Alzheimer's disease (AD). Our study sought to determine whether there were similar alterations in serial position learning among asymptomatic persons at risk for AD as a result of parental family history. Subjects included 623 asymptomatic middle-aged children of patients with AD (median, 53 years) and 157 control participants whose parents survived to at least age 70 without AD or other memory disorders. All participants were administered the Rey Auditory Verbal Learning Test, which requires learning and recall of 15 unrelated nouns. There was no significant difference in total words recalled between the AD children and control groups. However, compared with controls, AD children exhibited a significantly greater tendency to recall words from the end (recency) versus beginning (primacy) of the list. Serial position effects were unrelated to apolipoprotein allele epsilon 4 or depressive symptoms. Asymptomatic persons at risk for AD by virtue of family history do not show a difference in total words recalled compared with controls, but they exhibit a distinctly different serial position curve, suggesting greater reliance on immediate as opposed to episodic memory. This is the same serial position pattern observed in mild AD, seen here in reduced severity. Longitudinal follow-up is planned to determine whether changes in serial position patterns are a meaningful marker for preclinical detection of AD.

  1. A serial-kinematic nanopositioner for high-speed atomic force microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Wadikhaye, Sachin P., E-mail: sachin.wadikhaye@uon.edu.au; Yong, Yuen Kuan; Reza Moheimani, S. O. [School of Electrical Engineering and Computer Science, The University of Newcastle, Callaghan, NSW (Australia)

    2014-10-15

    A flexure-guided serial-kinematic XYZ nanopositioner for high-speed Atomic Force Microscopy is presented in this paper. Two aspects influencing the performance of serial-kinematic nanopositioners are studied in this work. First, mass reduction by using tapered flexures is proposed to increased the natural frequency of the nanopositioner. 25% increase in the natural frequency is achieved due to reduced mass with tapered flexures. Second, a study of possible sensor positioning in a serial-kinematic nanopositioner is presented. An arrangement of sensors for exact estimation of cross-coupling is incorporated in the proposed design. A feedforward control strategy based on phaser approach is presented to mitigate the dynamics and nonlinearity in the system. Limitations in design approach and control strategy are discussed in the Conclusion.

  2. A serial-kinematic nanopositioner for high-speed atomic force microscopy

    International Nuclear Information System (INIS)

    Wadikhaye, Sachin P.; Yong, Yuen Kuan; Reza Moheimani, S. O.

    2014-01-01

    A flexure-guided serial-kinematic XYZ nanopositioner for high-speed Atomic Force Microscopy is presented in this paper. Two aspects influencing the performance of serial-kinematic nanopositioners are studied in this work. First, mass reduction by using tapered flexures is proposed to increased the natural frequency of the nanopositioner. 25% increase in the natural frequency is achieved due to reduced mass with tapered flexures. Second, a study of possible sensor positioning in a serial-kinematic nanopositioner is presented. An arrangement of sensors for exact estimation of cross-coupling is incorporated in the proposed design. A feedforward control strategy based on phaser approach is presented to mitigate the dynamics and nonlinearity in the system. Limitations in design approach and control strategy are discussed in the Conclusion

  3. [Population policy and women: the relevance of previous studies].

    Science.gov (United States)

    De Barbieri, M T

    1983-01-01

    participation, and the role of women in society. Moreover, the literature concerning fertility decline contains numerous statements by both those opposed to and in favor of birth control, that improving the status of women is 1 of the most effective means of reducing population growth. It can then be asked what changes in the role of women in Mexico will attend application of a fertility reduction policy. The crude birth rate declined from 44.2 in 1970 to 34.4 in 1980, with fertility falling among all age groups but especially among women over 40. The decline occurred primarily among urban nonmanual occupations. More research must be done on recent fertility change in Mexico and on related changes in the role orientations of men and women in different classes and life cycle stages, that have occurred at various stages of the population debate.

  4. KANBAN allocation in a serial suply chain

    Directory of Open Access Journals (Sweden)

    Guillermo Andrés Sánchez C.

    2012-06-01

    Full Text Available The aim of this project is to simulate a Kanban system using N stages with the objective of maintaining an acceptable throughput and mean system time. The document shows the production systems where Kanban is applicable and what the potential benefits are. A serial of simulations will be done using a demand given by a poison distribution with rate λ ^ ext. The simulation aimed to find the best number of withdrawal Kanban on all stages when the values of μ (for exponential distribution of the process and λ ^ ext increase and decrease. At the end of this simulation, the best way to allocate the withdrawal Kanban over N stages with the objective of maintaining acceptable throughput and mean system time will be clearer thus the conclusions of this work will be done.

  5. The effect and complication of botulinum toxin type a injection with serial casting for the treatment of spastic equinus foot.

    Science.gov (United States)

    Lee, Sook Joung; Sung, In Young; Jang, Dae Hyun; Yi, Jin Hwa; Lee, Jin Ho; Ryu, Ju Seok

    2011-06-01

    To identify the effect of serial casting combined with Botulinum toxin type A (BTX-A) injection on spastic equinus foot. Twenty-nine children with cerebral palsy who had equinus foot were recruited from the outpatient clinic of Rehabilitation Medicine. The children were divided into 2 groups, one of which received serial casting after BTX-A injection, and the other which only received BTX-A injection. Serial casting started 3 weeks after the BTX-A injection, and was changed weekly for 3 times. Spasticity of the ankle joint was evaluated using the modified Ashworth scale (MAS), and the modified Tardieu scale (MTS). Gait pattern was measured using the physician's rating scale (PRS). The degree of ankle dorsiflexion and the MAS improved significantly until 12 weeks following the BTX-A injection in the serial casting group (pcasting. Our study demonstrated that the effect of BTX-A injection with serial casting was superior and lasted longer than the effect of BTX-A injection only in patients with spastic equinus foot. We therefore recommend BTX-A injection with serial casting for the treatment of equinus foot. However, physicians must also consider the possible complications associated with serial casting.

  6. Biceps Tendon Lengthening Surgery for Failed Serial Casting Patients With Elbow Flexion Contractures Following Brachial Plexus Birth Injury.

    Science.gov (United States)

    Nath, Rahul K; Somasundaram, Chandra

    2016-01-01

    Assessment of surgical outcomes of biceps tendon lengthening (BTL) surgery in obstetric brachial plexus injury (OBPI) patients with elbow flexion contractures, who had unsuccessful serial casting. Serial casting and splinting have been shown to be effective in correcting elbow flexion contractures in OBPI. However, the possibilities of radial head dislocations and other complications have been reported in serial casting and splinting. Literature indicates surgical intervention when such nonoperative techniques and range-of-motion exercises fail. Here, we demonstrated a significant reduction of the contractures of the affected elbow and improvement in arm length to more normal after BTL in these patients, who had unsuccessful serial casting. Ten OBPI patients (6 girls and 4 boys) with an average age of 11.2 years (4-17.7 years) had BTL surgery after unsuccessful serial casting. Mean elbow flexion contracture was 40° before and 37° (average) after serial casting. Mean elbow flexion contracture was reduced to 8° (0°-20°) post-BTL surgical procedure with an average follow-up of 11 months. This was 75% improvement and statistically significant (P casting. These OBPI patients in our study had 75% significant reduction in elbow flexion contractures and achieved an improved and more normal length of the affected arm after the BTL surgery when compared to only 7% insignificant reduction and no improvement in arm length after serial casting.

  7. Policy Forum: Studying Eyewitness Investigations in the Field

    Science.gov (United States)

    Dawes, Robyn; Jacoby, Larry L.; Kahneman, Daniel; Lempert, Richard; Roediger, Henry L.; Rosenthal, Robert

    2007-01-01

    This article considers methodological issues arising from recent efforts to provide field tests of eyewitness identification procedures. We focus in particular on a field study (Mecklenburg 2006) that examined the “double blind, sequential” technique, and consider the implications of an acknowledged methodological confound in the study. We explain why the confound has severe consequences for assessing the real-world implications of this study. PMID:17610149

  8. Viscous hydrophilic injection matrices for serial crystallography

    Directory of Open Access Journals (Sweden)

    Gabriela Kovácsová

    2017-07-01

    Full Text Available Serial (femtosecond crystallography at synchrotron and X-ray free-electron laser (XFEL sources distributes the absorbed radiation dose over all crystals used for data collection and therefore allows measurement of radiation damage prone systems, including the use of microcrystals for room-temperature measurements. Serial crystallography relies on fast and efficient exchange of crystals upon X-ray exposure, which can be achieved using a variety of methods, including various injection techniques. The latter vary significantly in their flow rates – gas dynamic virtual nozzle based injectors provide very thin fast-flowing jets, whereas high-viscosity extrusion injectors produce much thicker streams with flow rates two to three orders of magnitude lower. High-viscosity extrusion results in much lower sample consumption, as its sample delivery speed is commensurate both with typical XFEL repetition rates and with data acquisition rates at synchrotron sources. An obvious viscous injection medium is lipidic cubic phase (LCP as it is used for in meso membrane protein crystallization. However, LCP has limited compatibility with many crystallization conditions. While a few other viscous media have been described in the literature, there is an ongoing need to identify additional injection media for crystal embedding. Critical attributes are reliable injection properties and a broad chemical compatibility to accommodate samples as heterogeneous and sensitive as protein crystals. Here, the use of two novel hydrogels as viscous injection matrices is described, namely sodium carboxymethyl cellulose and the thermo-reversible block polymer Pluronic F-127. Both are compatible with various crystallization conditions and yield acceptable X-ray background. The stability and velocity of the extruded stream were also analysed and the dependence of the stream velocity on the flow rate was measured. In contrast with previously characterized injection media, both new

  9. The Global Politics of Policy Circulation in Higher Education: A Case Study of Paraguay 1998-2008

    Science.gov (United States)

    Britez, Rodrigo Gustavo

    2010-01-01

    This dissertation is concerned with the idea of global policy transfer, as it has increasingly appeared in the literature of policy studies, and has been used to understand recent educational policy transformations around the world. To carry out this investigation, I have conducted a case study of higher education in Paraguay in order to determine…

  10. Handbook of serial communications interfaces a comprehensive compendium of serial digital input/output (I/O) standards

    CERN Document Server

    Frenzel, Louis

    2015-01-01

    This book catalogs the most popular and commonly used serial-port interfaces and provides details on the specifications and the latest standards, enabling you to select an interface for a new design or verify that an interface is working correctly. Each chapter is based on a different interface and is written in an easy to follow, standard format. With this book you will learn: The most widely used serial interfacesHow to select the best serial interface for a specific application or designThe trade-offs between data rate and distance (length or range)The operation and benefits of serial

  11. African Journal of Drug and Alcohol Studies: Editorial Policies

    African Journals Online (AJOL)

    Focus and Scope. The "African Journal of Drug & Alcohol Studies" is an international scientific journal published by the African Centre for Research and Information on Substance Abuse (CRISA). The Journal publishes original research, evaluation studies, case reports, review articles and book reviews of high scholarly ...

  12. Risk policies and risk perceptions: a comparative study of environmental health risk policy and perception in six European countries

    NARCIS (Netherlands)

    Bröer, C.; Moerman, G.; Spruijt, P.; van Poll, R.

    2014-01-01

    This paper explores the influence that health risk policies have on the citizens’ perceptions of those health risks. Previously, detailed mixed methods research revealed that noise annoyance policies shaped noise perception. This idea is now applied to nine different environmental health risks in

  13. Evaluation of Esophageal Anastomotic Integrity With Serial Pleural Amylase Levels.

    Science.gov (United States)

    Miller, Daniel L; Helms, Gerald A; Mayfield, William R

    2018-01-01

    pneumonia on POD 10; no leak was ever identified, and the patient had been eating for 3 days before death. Complications occurred in 15 patients (33%), most commonly respiratory; no respiratory issues occurred in PAL-only evaluated patients. No late anastomotic leaks occurred in any patient while in the hospital or after discharge. Serial PALs for the detection of esophageal anastomotic leaks proved to be accurate, safe, and inexpensive. Elimination of barium swallows and computed tomography scans for evaluation of anastomotic integrity may decrease aspiration risks as well as associated pulmonary failure during the postoperative period. Serial PALs may be the preferred method of detecting an anastomotic leak after esophagectomy. A prospective randomized study is warranted. Copyright © 2018 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  14. Feasibility of multi-sector policy measures that create activity-friendly environments for children: results of a Delphi study

    Directory of Open Access Journals (Sweden)

    Aarts Marie-Jeanne

    2011-12-01

    Full Text Available Abstract Background Although multi-sector policy is a promising strategy to create environments that stimulate physical activity among children, little is known about the feasibility of such a multi-sector policy approach. The aims of this study were: to identify a set of tangible (multi-sector policy measures at the local level that address environmental characteristics related to physical activity among children; and to assess the feasibility of these measures, as perceived by local policy makers. Methods In four Dutch municipalities, a Delphi study was conducted among local policy makers of different policy sectors (public health, sports, youth and education, spatial planning/public space, traffic and transportation, and safety. In the first Delphi round, respondents generated a list of possible policy measures addressing three environmental correlates of physical activity among children (social cohesion, accessibility of facilities, and traffic safety. In the second Delphi round, policy makers weighted different feasibility aspects (political feasibility, cultural/community acceptability, technical feasibility, cost feasibility, and legal feasibility and assessed the feasibility of the policy measures derived from the first round. The third Delphi round was aimed at reaching consensus by feedback of group results. Finally, one overall feasibility score was calculated for each policy measure. Results Cultural/community acceptability, political feasibility, and cost feasibility were considered most important feasibility aspects. The Delphi studies yielded 16 feasible policy measures aimed at physical and social environmental correlates of physical activity among children. Less drastic policy measures were considered more feasible, whereas environmental policy measures were considered less feasible. Conclusions This study showed that the Delphi technique can be a useful tool in reaching consensus about feasible multi-sector policy measures. The

  15. Climate policies in a second-best world-A case study on India

    International Nuclear Information System (INIS)

    Mathy, Sandrine; Guivarch, Celine

    2010-01-01

    The aim of this article is to analyze the potential for synergies between climate policies and development in a case study on India focusing on the power sector sub-optimalities. To do so, we use IMACLIM-R, a dynamic recursive energy-economy model that represents a second best world with market imperfections and short-run adjustments constraints along a long-term growth path. The analysis suggests (i) global carbon pricing induces prohibitive macroeconomic costs for the Indian economy, even in the case of significant financial transfers associated with a global cap-and-trade system and a 'Contraction and Convergence in 2100' allocation scheme and (ii) the most cost efficient climate policies are not uniform carbon pricing only. The implementation of domestic policies suited to the national context, for instance targeting sub-optimalities in the power sector for India, allows reducing significantly the macroeconomic costs induced by international mitigation policies.

  16. Developing Public Policies for New Welfare Technologies – A Case Study of Telemedicine and Telehomecare

    DEFF Research Database (Denmark)

    Tambo, Torben

    2012-01-01

    and communication-based technologies (ICT) for homecare and monitoring (telemedicine, telehomecare). Despite major investments and national commitment, public policies have not yet found a general approach to move from technological and clinical opportunity and into large-scale regular use of the technology...... (normalisation). This article provides two case studies from Denmark; one case with hypertension monitoring at a local level and another case on national policy implementation through funding of selected demonstration projects. Among the findings are that policy-making processes certainly face major challenges...... in capturing research and development for the transition of technologies into working practice. Furthermore, policy approaches of supporting experimentation and demonstration are found inadequate in promoting technology into a level of normalisation in highly cross-organisational operational environments...

  17. A study on the establishment of national nuclear foreign policy

    International Nuclear Information System (INIS)

    Choi, Y.M.; Kim, H.S.; Lee, K.S.; Lee, B.Y.; Lee, J.S.; Choi, Y.L.

    1993-01-01

    The overall objective of this study is to analyze international non-proliferation circumstances, to suggest national strategies and tactics for international meetings non-proliferation and peaceful uses of nuclear energy, and to establish domestic non-proliferation systems for international credibility. This study suggests two revision proposals for the IAEA Statute Article VI as a means for the permanent membership in the Board, evaluates benefits and losses of the membership of the international export control regime, and suggests strategies for building a domestics nuclear export control system. This study contributes to enhancing international credibility and promoting self-reliance of nuclear technology in Korea. (Author)

  18. Critical Studies in Teaching and Learning: Editorial Policies

    African Journals Online (AJOL)

    Critical Studies in Teaching and Learning is a peer-reviewed journal that publishes .... Data access and retention: Authors should ensure accessibility of raw data to other ... a manuscript, the author/s retain the rights to the published material.

  19. Obstacles and facilitators of open visiting policy in Intensive Care Units:A qualitative study

    Directory of Open Access Journals (Sweden)

    Shiva Khaleghparast

    2016-07-01

    Full Text Available Open visiting policy in intensive care units is proposed as an essential requirement for patients and their families, so this study is aimed to explain open visiting policy obstacles and facilitators from patients, families and health team members’ viewpoint. This qualitative study implemented in intensive care units of a hospital specialized in cardiology in Tehran-Iran. Patients’, families’, nurses’, doctors’ and guards’ viewpoint was determined regarding open visiting policy obstacles and facilitators by semi-structured interviews. Data analysis method was conventional approach of qualitative content analysis with thematic technique. Data analysis was performed using Max QDA10 software. Two main categories of data regarding open visiting obstacles and facilitators were extracted. Factors related to service systems and visitors derived from open visiting obstacles, and factors related to management system and personnel derived from open visiting facilitators. One of the most important obstacles of open visiting policy implementation is shortage of staff and personnel negative attitude. Regarding open visiting policy facilitators, designing visiting cards for close family and observing specific rules, modification of intensive care unit structure and facilities for families are useful. Finally, what is important as an open visiting policy implementation facilitator is presence of nursing profession as a humanitarian and ethical profession.

  20. European wine policy and perceptions of Moravian winemakers: a pilot study in the Czech Republic

    Directory of Open Access Journals (Sweden)

    Petr Koráb

    2012-01-01

    Full Text Available European wine policy is a significant factor influencing winemakers in the European Union. This paper examines perception of this policy by winemakers and other persons working in Czech wine sector on the sample of respondents. Methodological triangulation consisting of non-structured interview and semantic differential was chosen. Field research was carried out, therefore the study uses primary data. Application of the methodology along with the method of evaluation of data creates an original approach which may be applied on several other research questions. General perception of European Wine Policy is complemented with its impact on competitiveness, practical running of vineyards and winery and on future development of winery. Data is statistically evaluated within categories of respondents. Special emphasis is placed on direct payments as a controversial factor of the policy. The policy is perceived as bureaucratic (“all respondents” x = 4.56, and among micro winemakers discriminating (x = 4.5, selfish (x = 4.5 and malfunctioning (x = 3.5. “Professional” winemakers perceive the impact on competitiveness in the Czech market as rather positive (x = 2.67. This study represents pilot research on perception of European Wine Policy by owners of wineries, viticulturists, micro winemakers, a sommelier and a representative of marketing-supporting institution, conducted in the Czech Republic. The author also outlines further direction of research, as the topic is not paid enough scientific attention.

  1. Economic policy and private investment since the oil crisis: a comparative study of France and Germany

    Energy Technology Data Exchange (ETDEWEB)

    Artus, P. (INSEE, Paris, France); Muet, P.A.; Palinkas, P.; Pauly, P.

    1981-05-01

    A comparative analysis of private investment in France and Germany is made with respect to single-equation analysis and to the simulation of policy scenarios within large-scale econometric models for either country. The METRIC and SYSIFO models used in this study are similar enough to discriminate between those results diverging due to specification differences and those discrepancies, which can reasonably be attributed to structural differences between both economies. The basic results on the specification issue are: (1) a putty-clay model sufficiently represents French and German production structures; (2) the accelerator mechanism clearly dominates the effects of relative prices; and (3) the influence of profits in both countries appears to be mainly on the timing of investment, to a minor extent only on the volume. The policy simulations indicate that several of the policy measures are inefficient for both countries in the given historical context. For both countries it seems as if particularly the outside lag of monetary policy and delayed reverse effects of temporary discretionary measures tend to obscure the counter-cyclical character of stabilization policy. Finally, some further scenarios suggest that the performance during the crisis could have been improved: with a distinctly counter-cyclical policy in France, and with something of a neutral policy in Germany. A globally optimal strategy in an optimal control sense has, however, not been developed. Generally, confirming previous studies for other countries, it seems as if a fully-efficient discretionary stabilization policy via private investment is hardly attainable. 41 references, 6 figures, 11 tables.

  2. A Serializer ASIC for High Speed Data Transmission in Cryogenic and HiRel Environment

    CERN Document Server

    Liu, T; The ATLAS collaboration

    2010-01-01

    A high speed 16:1 serializer ASIC has been developed using a commercial 0.25 μm silicon-on-sapphire CMOS technology. At room temperature the ASIC operates from 4.0 to 5.7 Gbps with power consumption of 463 mW. The total jitter is 62 ps at the bit error rate of 10-12 at 5 Gbps. A 200-MeV proton beam test indicates that the ASIC is suitable for high energy physics applications. A liquid nitrogen temperature test indicates that the ASIC may be used at cryogenic temperature applications. The reliability of the serializer at liquid nitrogen temperature is to be studied. A 6-lane serializer array with 10 Gbps/lane with redundancy capability is under development.

  3. Credible baseline analysis for multi-model public policy studies

    Energy Technology Data Exchange (ETDEWEB)

    Parikh, S.C.; Gass, S.I.

    1981-01-01

    The nature of public decision-making and resource allocation is such that many complex interactions can best be examined and understood by quantitative analysis. Most organizations do not possess the totality of models and needed analytical skills to perform detailed and systematic quantitative analysis. Hence, the need for coordinated, multi-organization studies that support public decision-making has grown in recent years. This trend is expected not only to continue, but to increase. This paper describes the authors' views on the process of multi-model analysis based on their participation in an analytical exercise, the ORNL/MITRE Study. One of the authors was the exercise coordinator. During the study, the authors were concerned with the issue of measuring and conveying credibility of the analysis. This work led them to identify several key determinants, described in this paper, that could be used to develop a rating of credibility.

  4. Energy policy study. Volume 10. Nuclear power regulation

    International Nuclear Information System (INIS)

    Nikodem, Z.D.; Reynolds, A.W.; Clark, R.G.

    1980-05-01

    This report examines the programs for regulating the safety, design, and operation of domestic nuclear power plants. The first part of the study describes the Federal and State regulatory procedures. It describes the legal foundations for the Federal licensing process and the associated State regulatory activities. It then analyzes the aspects of these procedures that affect the cost and supply of nuclear-generated electricity. The second part of this study examines the effects of nuclear safety regulations on the planning and construction lead time for nuclear power stations, the cost of nuclear power, and, ultimately, the decision to invest in nuclear power

  5. Empirical Studies on Financial Intermediation and Corporate Policies

    NARCIS (Netherlands)

    P. Daniševská (Petra)

    2004-01-01

    textabstractPetra Daniševská was born in Pardubice, the Czech Republic, in 1975. From 1993 till 1999 she studied financial economics at the University of Economics in Prague. During this time she spent half a year as an exchange student at the University of Plymouth in the U.K. She furthermore

  6. Reducing US cardiovascular disease burden and disparities through national and targeted dietary policies: A modelling study.

    Directory of Open Access Journals (Sweden)

    Jonathan Pearson-Stuttard

    2017-06-01

    % SSB tax. Neither the MMC nor the individual national economic policies would significantly reduce CVD socio-economic disparities. However, the SNAP-targeted intervention might potentially reduce CVD disparities between SNAP participants and SNAP-ineligible individuals, by approximately 8% (10 DPPs per 100,000 population. The combined policy approach might save more lives than any single policy studied (approximately 230,000 DPPs by 2030 while also significantly reducing disparities, by approximately 6% (7 DPPs per 100,000 population. Limitations include our effect estimates in the model; these estimates use interventional and prospective observational studies (not exclusively randomised controlled trials. They are thus imperfect and should be interpreted as the best available evidence. Another key limitation is that we considered only CVD outcomes; the policies we explored would undoubtedly have additional beneficial effects upon other diseases. Further, we did not model or compare the cost-effectiveness of each proposed policy.Fiscal strategies targeting diet might substantially reduce CVD burdens. A national 10% F&V subsidy would save by far the most lives, while a 30% F&V subsidy targeting SNAP participants would most reduce socio-economic disparities. A combined policy would have the greatest overall impact on both mortality and socio-economic disparities.

  7. Utilization of serial resources in libraries of selected tertiary ...

    African Journals Online (AJOL)

    Information Impact: Journal of Information and Knowledge Management ... security personnel for adequate monitoring of the serial materials, as well as the need for authors and stakeholders in education to donate more serial materials in order to enrich the collections in the library and enhance academic performance.

  8. The Effect of Concurrent Semantic Categorization on Delayed Serial Recall

    Science.gov (United States)

    Acheson, Daniel J.; MacDonald, Maryellen C.; Postle, Bradley R.

    2011-01-01

    The influence of semantic processing on the serial ordering of items in short-term memory was explored using a novel dual-task paradigm. Participants engaged in 2 picture-judgment tasks while simultaneously performing delayed serial recall. List material varied in the presence of phonological overlap (Experiments 1 and 2) and in semantic content…

  9. Effects of Serial Rehearsal Training on Memory Search

    Science.gov (United States)

    McCauley, Charley; And Others

    1976-01-01

    Half the subjects were trained to use a serial rehearsal strategy during target set storage and half were given no strategy training. The results indicate that the rate of memory search is IQ-related, and that serial rehearsal training facilitates memory search when rehearsal is covert. (Author/BW)

  10. Indexing Serialized Fiction: May the Force Be with You.

    Science.gov (United States)

    Barr, Melissa M.

    The adult novel offers indexers an unusual opportunity to create a serialized fiction index. This research paper involved designing and creating a Character Index, Thesaurus, Glossary, and Abstract (with descriptors) for 21 novels based on the "Star Wars" movies. The novels are an unusual example of serialized fiction featuring main…

  11. Infants' Memory Processing of a Serial List: List Length Effects.

    Science.gov (United States)

    Gulya, Michele; Sweeney, Becky; Rovee-Collier, Carolyn

    1999-01-01

    Three experiments demonstrated that increasing the length of a mobile serial list impaired 6-month olds' memory for serial order. Findings indicated that the primacy effect was absent on a 24-hour delayed recognition test and was exhibited on a reactivation test, adding to growing evidence that young infants possess two functionally distinct…

  12. Challenges and opportunities for policy decisions to address health equity in developing health systems: case study of the policy processes in the Indian state of Orissa

    Directory of Open Access Journals (Sweden)

    Gopalan Saji S

    2011-11-01

    Full Text Available Abstract Introduction Achieving health equity is a pertinent need of the developing health systems. Though policy process is crucial for planning and attaining health equity, the existing evidences on policy processes are scanty in this regard. This article explores the magnitude, determinants, challenges and prospects of 'health equity approach' in various health policy processes in the Indian State of Orissa - a setting comparable with many other developing health systems. Methods A case-study involving 'Walt-Gilson Policy Triangle' employed key-informant interviews and documentary reviews. Key informants (n = 34 were selected from the departments of Health and Family Welfare, Rural Development, and Women and Child Welfare, and civil societies. The documentary reviews involved various published and unpublished reports, policy pronouncements and articles on health equity in Orissa and similar settings. Results The 'health policy agenda' of Orissa was centered on 'health equity' envisaging affordable and equitable healthcare to all, integrated with public health interventions. However, the subsequent stages of policy process such as 'development, implementation and evaluation' experienced leakage in the equity approach. The impediment for a comprehensive approach towards health equity was the nexus among the national and state health priorities; role, agenda and capacity of actors involved; and existing constraints of the healthcare delivery system. Conclusion The health equity approach of policy processes was incomprehensive, often inadequately coordinated, and largely ignored the right blend of socio-medical determinants. A multi-sectoral, unified and integrated approach is required with technical, financial and managerial resources from different actors for a comprehensive 'health equity approach'. If carefully geared, the ongoing health sector reforms centered on sector-wide approaches, decentralization, communitization and involvement of

  13. Smoke-Free Public Policies and Voluntary Policies in Personal Settings in Tbilisi, Georgia: A Qualitative Study.

    Science.gov (United States)

    Berg, Carla J; Smith, Samantha A; Bascombe, Ta Misha; Maglakelidze, Nino; Starua, Lela; Topuridze, Marina

    2016-01-25

    Georgia has limited tobacco control policies, particularly in the area of smoke-free public policies, which may influence the adoption of smoke-free home rules. We qualitatively examined knowledge about and reactions to public and personal smoke-free policies among Tbilisi residents. In Spring 2014, we conducted six focus groups among 47 total participants--two among male smokers, one among male nonsmokers, two among female smokers, and one among female nonsmokers. Our sample was 48.9% male and 70.2% past 30-day smokers. Most believed that SHS was dangerous, with particular concern regarding the impact of SHS on children and pregnant women. Many had misconceptions about how to protect others from SHS and the effectiveness of some approaches. Many indicated that they had some type of home rules, but few reported a complete ban on smoking in the home. Even when some restrictions were in place, they rarely were effective or enforced. Common concerns about the partial smoke-free public policy in Georgia included its economic impact, perceived discrimination among smokers, and the policy being against the Georgian culture. These concerns were heightened when participants were asked about the possible implementation of a complete smoke-free policy. Educational programs are needed to promote smoke-free policies in Georgia.

  14. Developing consensus-based policy solutions for medicines adherence for Europe: a delphi study

    Science.gov (United States)

    2012-01-01

    Background Non-adherence to prescribed medication is a pervasive problem that can incur serious effects on patients’ health outcomes and well-being, and the availability of resources in healthcare systems. This study aimed to develop practical consensus-based policy solutions to address medicines non-adherence for Europe. Methods A four-round Delphi study was conducted. The Delphi Expert Panel comprised 50 participants from 14 countries and was representative of: patient/carers organisations; healthcare providers and professionals; commissioners and policy makers; academics; and industry representatives. Participants engaged in the study remotely, anonymously and electronically. Participants were invited to respond to open questions about the causes, consequences and solutions to medicines non-adherence. Subsequent rounds refined responses, and sought ratings of the relative importance, and operational and political feasibility of each potential solution to medicines non-adherence. Feedback of individual and group responses was provided to participants after each round. Members of the Delphi Expert Panel and members of the research group participated in a consensus meeting upon completion of the Delphi study to discuss and further refine the proposed policy solutions. Results 43 separate policy solutions to medication non-adherence were agreed by the Panel. 25 policy solutions were prioritised based on composite scores for importance, and operational and political feasibility. Prioritised policy solutions focused on interventions for patients, training for healthcare professionals, and actions to support partnership between patients and healthcare professionals. Few solutions concerned actions by governments, healthcare commissioners, or interventions at the system level. Conclusions Consensus about practical actions necessary to address non-adherence to medicines has been developed for Europe. These actions are also applicable to other regions. Prioritised

  15. State of Data Guidance in Journal Policies: A Case Study in Oncology

    Directory of Open Access Journals (Sweden)

    Deborah H. Charbonneau

    2015-06-01

    Full Text Available This article reports the results of a study examining the state of data guidance provided to authors by 50 oncology journals. The purpose of the study was the identification of data practices addressed in the journals’ policies. While a number of studies have examined data sharing practices among researchers, little is known about how journals address data sharing. Thus, what was discovered through this study has practical implications for journal publishers, editors, and researchers. The findings indicate that journal publishers should provide more meaningful and comprehensive data guidance to prospective authors. More specifically, journal policies requiring data sharing, should direct researchers to relevant data repositories, and offer better metadata consultation to strengthen existing journal policies. By providing adequate guidance for authors, and helping investigators to meet data sharing mandates, scholarly journal publishers can play a vital role in advancing access to research data.

  16. Effects of serial and concurrent training on receptive identification tasks: A Systematic replication.

    Science.gov (United States)

    Wunderlich, Kara L; Vollmer, Timothy R

    2017-07-01

    The current study compared the use of serial and concurrent methods to train multiple exemplars when teaching receptive language skills, providing a systematic replication of Wunderlich, Vollmer, Donaldson, and Phillips (2014). Five preschoolers diagnosed with developmental delays or autism spectrum disorders were taught to receptively identify letters or letter sounds. Subjects learned the target stimuli slightly faster in concurrent training and a high degree of generalization was obtained following both methods of training, indicating that both the serial and concurrent methods of training are efficient and effective instructional procedures. © 2017 Society for the Experimental Analysis of Behavior.

  17. Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal

    Directory of Open Access Journals (Sweden)

    Sam Horrell

    2016-07-01

    Full Text Available Relating individual protein crystal structures to an enzyme mechanism remains a major and challenging goal for structural biology. Serial crystallography using multiple crystals has recently been reported in both synchrotron-radiation and X-ray free-electron laser experiments. In this work, serial crystallography was used to obtain multiple structures serially from one crystal (MSOX to study in crystallo enzyme catalysis. Rapid, shutterless X-ray detector technology on a synchrotron MX beamline was exploited to perform low-dose serial crystallography on a single copper nitrite reductase crystal, which survived long enough for 45 consecutive 100 K X-ray structures to be collected at 1.07–1.62 Å resolution, all sampled from the same crystal volume. This serial crystallography approach revealed the gradual conversion of the substrate bound at the catalytic type 2 Cu centre from nitrite to nitric oxide, following reduction of the type 1 Cu electron-transfer centre by X-ray-generated solvated electrons. Significant, well defined structural rearrangements in the active site are evident in the series as the enzyme moves through its catalytic cycle, namely nitrite reduction, which is a vital step in the global denitrification process. It is proposed that such a serial crystallography approach is widely applicable for studying any redox or electron-driven enzyme reactions from a single protein crystal. It can provide a `catalytic reaction movie' highlighting the structural changes that occur during enzyme catalysis. The anticipated developments in the automation of data analysis and modelling are likely to allow seamless and near-real-time analysis of such data on-site at some of the powerful synchrotron crystallographic beamlines.

  18. Developing national obesity policy in middle-income countries: a case study from North Africa.

    Science.gov (United States)

    Holdsworth, Michelle; El Ati, Jalila; Bour, Abdellatif; Kameli, Yves; Derouiche, Abdelfettah; Millstone, Erik; Delpeuch, Francis

    2013-12-01

    The prevalence of overweight and obesity is a rapidly growing threat to public health in both Morocco and Tunisia, where it is reaching similar proportions to high-income countries. Despite this, a national strategy for obesity does not exist in either country. The aim of this study was to explore the views of key stakeholders towards a range of policies to prevent obesity, and thus guide policy makers in their decision making on a national level. Using Multicriteria Mapping, data were gathered from 82 stakeholders (from 33 categories in Morocco and 36 in Tunisia) who appraised 12 obesity policy options by reference to criteria of their own choosing. The feasibility of policies in practical or political terms and their cost were perceived as more important than how effective they would be in reducing obesity. There was most consensus and preference for options targeting individuals through health education, compared with options that aimed at changing the environment, i.e. modifying food supply and demand (providing healthier menus/changing food composition/food sold in schools); controlling information (advertising controls/mandatory labelling) or improving access to physical activity. In Tunisia, there was almost universal consensus that at least some environmental-level options are required, but in Morocco, participants highlighted the need to raise awareness within the population and policy makers that obesity is a public health problem, accompanied by improving literacy before such measures would be accepted. Whilst there is broad interest in a range of policy options, those measures targeting behaviour change through education were most valued. The different socioeconomic, political and cultural contexts of countries need to be accounted for when prioritizing obesity policy. Obesity was not recognized as a major public health priority; therefore, convincing policy makers about the need to prioritize action to prevent obesity, particularly in Morocco, will be

  19. Developing national obesity policy in middle-income countries: a case study from North Africa

    Science.gov (United States)

    Holdsworth, Michelle; El Ati, Jalila; Bour, Abdellatif; Kameli, Yves; Derouiche, Abdelfettah; Millstone, Erik; Delpeuch, Francis

    2013-01-01

    Background The prevalence of overweight and obesity is a rapidly growing threat to public health in both Morocco and Tunisia, where it is reaching similar proportions to high-income countries. Despite this, a national strategy for obesity does not exist in either country. The aim of this study was to explore the views of key stakeholders towards a range of policies to prevent obesity, and thus guide policy makers in their decision making on a national level. Methods Using Multicriteria Mapping, data were gathered from 82 stakeholders (from 33 categories in Morocco and 36 in Tunisia) who appraised 12 obesity policy options by reference to criteria of their own choosing. Results The feasibility of policies in practical or political terms and their cost were perceived as more important than how effective they would be in reducing obesity. There was most consensus and preference for options targeting individuals through health education, compared with options that aimed at changing the environment, i.e. modifying food supply and demand (providing healthier menus/changing food composition/food sold in schools); controlling information (advertising controls/mandatory labelling) or improving access to physical activity. In Tunisia, there was almost universal consensus that at least some environmental-level options are required, but in Morocco, participants highlighted the need to raise awareness within the population and policy makers that obesity is a public health problem, accompanied by improving literacy before such measures would be accepted. Conclusion Whilst there is broad interest in a range of policy options, those measures targeting behaviour change through education were most valued. The different socioeconomic, political and cultural contexts of countries need to be accounted for when prioritizing obesity policy. Obesity was not recognized as a major public health priority; therefore, convincing policy makers about the need to prioritize action to prevent

  20. Cluster Policy in the Light of Institutional Context—A Comparative Study of Transition Countries

    Directory of Open Access Journals (Sweden)

    Tine Lehmann

    2015-10-01

    Full Text Available The business environment in transition countries is often extraordinarily challenging for companies. The transition process these countries find themselves in leads to constant changes in the institutional environment. Hence, institutional voids prevail. These institutional voids cause competitive disadvantages for small and medium enterprises. Cluster policy can address these competitive disadvantages. As cluster policy generally aims at supporting companies’ competitive advantage by spurring innovation and productivity, it can help to bridge institutional voids. This article’s research question aims at analyzing and comparing cluster policies in the institutional context of two transition countries (Serbia and Tunisia and analyzes to what extent cluster policies in these two countries are adapted to institutional voids prevailing there. The case studies offer insights into apparent difficulties of clusters in bridging formal institutional voids, as well as, notably, into the informal void of skill mismatches in the labor market. Still, for some specific voids, clusters do at least implicitly assume a bridging role. While the cluster policies examined do not explicitly target the institutional voids identified, cluster management can—in the course of time—align its service offering more closely with these voids. Bottom-up designed cluster policies can play an especially important role in such an evolution towards bridging institutional voids.

  1. Serial femtosecond X-ray diffraction of enveloped virus microcrystals

    Directory of Open Access Journals (Sweden)

    Robert M. Lawrence

    2015-07-01

    Full Text Available Serial femtosecond crystallography (SFX using X-ray free-electron lasers has produced high-resolution, room temperature, time-resolved protein structures. We report preliminary SFX of Sindbis virus, an enveloped icosahedral RNA virus with ∼700 Å diameter. Microcrystals delivered in viscous agarose medium diffracted to ∼40 Å resolution. Small-angle diffuse X-ray scattering overlaid Bragg peaks and analysis suggests this results from molecular transforms of individual particles. Viral proteins undergo structural changes during entry and infection, which could, in principle, be studied with SFX. This is an important step toward determining room temperature structures from virus microcrystals that may enable time-resolved studies of enveloped viruses.

  2. Serial analysis of gene expression (SAGE) in rat liver regeneration

    International Nuclear Information System (INIS)

    Cimica, Velasco; Batusic, Danko; Haralanova-Ilieva, Borislava; Chen, Yonglong; Hollemann, Thomas; Pieler, Tomas; Ramadori, Giuliano

    2007-01-01

    We have applied serial analysis of gene expression for studying the molecular mechanism of the rat liver regeneration in the model of 70% partial hepatectomy. We generated three SAGE libraries from a normal control liver (NL library: 52,343 tags), from a sham control operated liver (Sham library: 51,028 tags), and from a regenerating liver (PH library: 53,061 tags). By SAGE bioinformatics analysis we identified 40 induced genes and 20 repressed genes during the liver regeneration. We verified temporal expression of such genes by real time PCR during the regeneration process and we characterized 13 induced genes and 3 repressed genes. We found connective tissue growth factor transcript and protein induced very early at 4 h after PH operation before hepatocytes proliferation is triggered. Our study suggests CTGF as a growth factor signaling mediator that could be involved directly in the mechanism of liver regeneration induction

  3. Reading Time Allocation Strategies and Working Memory Using Rapid Serial Visual Presentation

    Science.gov (United States)

    Busler, Jessica N.; Lazarte, Alejandro A.

    2017-01-01

    Rapid serial visual presentation (RSVP) is a useful method for controlling the timing of text presentations and studying how readers' characteristics, such as working memory (WM) and reading strategies for time allocation, influence text recall. In the current study, a modified version of RSVP (Moving Window RSVP [MW-RSVP]) was used to induce…

  4. Highlights in radiation measuring technique's - Serial Micro Channel SMC 2100

    International Nuclear Information System (INIS)

    Kandler, M.; Hoffmann, Ch.

    2002-01-01

    The Serial Micro Channel SMC 2100 offers an ''intelligent stand alone'' electronics for the radiation measuring technique's. First it is designed of being connected to a serial interface RS232 of a PC. With a RS485 serial interface on a PC, a network structure can be generated. It has all functional modules which are necessary for the measurement of detector signals. Hence it is possible to directly connect any detector for radiation measurement to a PC, laptop, or notebook. All variations can be operated without PC support too. It has a modular structure and consists of two blocks, the functional modules and the basic modules. The Serial Micro Channel SMC 2100 may be directly coupled to a detector, which therefore makes the realisation of an ''intelligent radiation detector'' with serial link RS232 or RS485. (orig.)

  5. Serial Entrepreneurship, Learning by Doing and Self-selection

    DEFF Research Database (Denmark)

    Rocha, Vera; Carneiro, Anabela; Varum, Celeste

    2015-01-01

    of the person-specific effect, using information on individuals’ past histories in paid employment, confirm that serial entrepreneurs exhibit, on average, a larger person-specific effect than non-serial business owners. Moreover, ignoring serial entrepreneurs’ self-selection overestimates learning by doing......It remains a question whether serial entrepreneurs typically perform better than their novice counterparts owing to learning by doing effects or mostly because they are a selected sample of higher-than-average ability entrepreneurs. This paper tries to unravel these two effects by exploring a novel...... empirical strategy based on continuous time duration models with selection. We use a large longitudinal matched employer-employee dataset that allows us to identify about 220,000 individuals who have left their first entrepreneurial experience, out of which over 35,000 became serial entrepreneurs. We...

  6. A study on the establishment of national nuclear foreign policy

    International Nuclear Information System (INIS)

    Oh, Keun Bae; Ham, Chul Hoon; Lee, Kwang Suk; Cho, Il Hoon; Lee, Byung Wook; Lee, Jae Sung; Lee, Byung Woon; Choi, Yung Lok; Koh, Han Suk

    1994-12-01

    This study is composed mainly of the current status of international non-proliferation, the NPT extension, IAEA Status, the circumstances of nuclear export control system, and the Vienna convention and London convention. The recent circumstances of the NPT have been analyzed. We established counter measures and strategies on the NPT extension conference. After reviewing the international export control system of NSG members, we suggested the factors which should be involved in the nuclear export control system. Also, U.S. systems on retransferring were intensively reviewed. In connection with the challenges coped with by the IAEA, several agenda have been reviewed and analyzed: the financing status of the Agency; the program 93+2 for the strengthening of effectiveness and improving of efficiency in the safeguards system. In connection with the amendment work of the Vienna Convention, we studied the major contents of four proposals which were suggested. In the case of the London Convention, the causes of maritime pollution and the kinds of sea dumping material were investigated. 3 figs, 13 tabs, 66 refs. (Author)

  7. A study on the establishment of national nuclear foreign policy

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Keun Bae; Ham, Chul Hoon; Lee, Kwang Suk; Cho, Il Hoon; Lee, Byung Wook; Lee, Jae Sung; Lee, Byung Woon; Choi, Yung Lok; Koh, Han Suk [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1994-12-01

    This study is composed mainly of the current status of international non-proliferation, the NPT extension, IAEA Status, the circumstances of nuclear export control system, and the Vienna convention and London convention. The recent circumstances of the NPT have been analyzed. We established counter measures and strategies on the NPT extension conference. After reviewing the international export control system of NSG members, we suggested the factors which should be involved in the nuclear export control system. Also, U.S. systems on retransferring were intensively reviewed. In connection with the challenges coped with by the IAEA, several agenda have been reviewed and analyzed: the financing status of the Agency; the program 93+2 for the strengthening of effectiveness and improving of efficiency in the safeguards system. In connection with the amendment work of the Vienna Convention, we studied the major contents of four proposals which were suggested. In the case of the London Convention, the causes of maritime pollution and the kinds of sea dumping material were investigated. 3 figs, 13 tabs, 66 refs. (Author).

  8. Illustrating the use of concepts from the discipline of policy studies in energy research: An explorative literature review

    NARCIS (Netherlands)

    Hoppe, Thomas; Coenen, Franciscus H.J.M.; van den Berg, Maya Marieke

    2016-01-01

    With the increasing challenges the energy sector faces, energy policy strategies and instruments are becoming ever more relevant. The discipline of policy studies might offer relevant concepts to enrich multidisciplinary energy research. The main research question of this article is: How can policy

  9. Pilot Study: Impact of Computer Simulation on Students' Economic Policy Performance. Pilot Study.

    Science.gov (United States)

    Domazlicky, Bruce; France, Judith

    Fiscal and monetary policies taught in macroeconomic principles courses are concepts that might require both lecture and simulation methods. The simulation models, which apply the principles gleened from comparative statistics to a dynamic world, may give students an appreciation for the problems facing policy makers. This paper is a report of a…

  10. Project ATTACK and Project VISTA: Benchmark studies on the road to NATO's early TNF policy

    International Nuclear Information System (INIS)

    Garrity, P.J.

    1994-01-01

    This paper is concerned with those studies and analyses that affected early NATO nuclear policy and force structure. The discussion focuses specifically on two open-quotes benchmarkclose quotes activities. Project VISTA and Project ATTACK. These two studies were chosen less because one can document their direct impact on NATO nuclear policy and more because they capture the state of thinking about tactical nuclear weapons at a particular point of time. Project VISTA offers an especially important benchmark in this respect. Project ATTACK is a rather different kind of benchmark. It is not a pathbreaking study. It is much narrower and more technical than VISTA. It appears to have received no public attention. Project ATTACK is interesting because it seems to capture a open-quotes nuts-and-boltsclose quotes feel for how U.S. (and thereby NATO) theater nuclear policy was evolving prior to MC 48. The background and context for Project VISTA and Project ATTACK are presented and discussed

  11. Air pollution and health studies in China--policy implications.

    Science.gov (United States)

    Chen, Bingheng; Kan, Haidong; Chen, Renjie; Jiang, Songhui; Hong, Chuanjie

    2011-11-01

    During the rapid economic development in China, ambient air pollutants in major cities, including PM10 (particulate matter with aerodynamic diameter air pollution levels in China are still at the higher end of the world level. Less information is available regarding changes in national levels of other pollutants such as PM2.5 and ozone. The Chinese Ministry of Environmental Protection (MOEP) set an index for "controlling/reducing total SO2 emissions" to evaluate the efficacy of air pollution control strategy in the country. Total SO2 emissions declined for the first time in 2007. Chinese epidemiologic studies evidenced adverse health effects of ambient air pollution similar to those reported from developed countries, though risk estimates on mortality/morbidity per unit increase of air pollutant are somewhat smaller than those reported in developed countries. Disease burden on health attributable to air pollution is relatively greater in China because of higher pollution levels. Improving ambient air quality has substantial and measurable public health benefits in China. It is recommended that the current Chinese air quality standards be updated/revised and the target for "controlling/reducing total SO2 emissions" be maintained and another target for "reducing total NO2 emissions" be added in view of rapid increase in motor vehicles. Continuous and persistent efforts should be taken to improve ambient air quality.

  12. Recent energy studies and energy policies in Turkey

    Energy Technology Data Exchange (ETDEWEB)

    Gullu, D.; Caglar, A.; Akdeniz, F. [Karadeniz Technical University, Trabzon (Turkey). Faculty of Education

    2001-07-01

    Currently, considerable attention has been focused on the energy sources and energy studies in Turkey. Indigenous energy consumption accounts for 37% of total energy consumption. The Turkish government's investment needs in the energy sector for the period 2000-2010 will be around 55 billion US dollars. Of this, about 81% is total planning investments. Conventional financing of major infrastructure projects would only increase the amount of foreign credit, thus the Ministry of Energy and Natural Resources (MENR) has conceived other options for financing projects. One option is the so-called Build, Operate, and Transfer (BOT) model, where private investors build and operate private sector generation for certain number of years, at which point they transfer ownership to the state. In June 1996, MENR introduced the Build, Own, and Operate (BOO) financing model. A major dilemma now faced by Turkey is how to invest in new electric power capacity while at the same time adhering to foreign debt ceilings to under lending rules set by the International Monetary Fund. Turkey has to adopt new long-term energy strategies to reduce the share of fossil fuels in the primary energy consumption. Recently, the development of alternative energy sources has been a major focus of the research effort in Turkey.

  13. Alternative Policy Study: Environment and energy in Europe and Central Asia 1990-2010. Energy-related environmental impacts of policy scenarios GEO-2000 alternative policy study

    NARCIS (Netherlands)

    Vuuren DP van; Bakkes JA; MNV

    2000-01-01

    Deze GEO-2000 studie naar alternatief beleid voor Europa en Centraal Azie is gericht op energie als een belangrijke kracht achter milieuproblemen in de hele regio. De studie heeft betrekking op klimaatverandering, verzuring, zomersmog, stedelijke luchtverontreiniging en het risico op dodelijke

  14. Climate policy studies by the Fridtjof Nansen Institute, ECON and Energy Data:10 Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    Andresen, S; Eikeland, P O; Eleri, E O; Fermann, G; Fredriksen, O; Halseth, A; Hansen, S; Haugland, T; Malnes, R; Skjaerseth, J B; Ottosen, R

    1993-07-01

    The overall focus is the relation between energy, environment and development on the national level and international co-operation concerning sustainable energy management and global environmental change. A series of country studies analyses the economic, political and institutional factors influencing energy, environment and climate policies. The role of non-state actors like NGOs and the energy industries in international environmental affairs is also closely examined. Strategies to enhance energy efficiency are studied with a particular focus on identifying and overcoming barriers to policy implementation. The ways in which developments in international energy markets affect the potential and scope of international environmental agreements are analysed, as are the impacts of different international environmental regimes on energy markets. Particular attention is paid on the opportunities and limitations of international institutions like the European Community, the United Nations, the multilateral development banks and GATT, in promoting international co-operation on energy and environmental issues. Strategies to overcome North/South conflicts over global environmental issues are examined, including issue linkages in international negotiations and North/South transfer of resources and technology. Another important area of sustainable production and consumption of energy in developing countries. Project titles are: 1) ''Leader'' and ''entrepreneur'' in international negotiations . A conceptual analysis. 2) Choosing climate policy. Decision theoretical premises. 3) Japan in the greenhouse responsibilities, policies and prospects for combating global warming. 4) Impacts on developing economies from changing trade regimes and growing international environmental concerns. 5) US energy policy in the greenhouse from the North slope forests to the Gulf Stream waters - this land was made for fossil fuels. 6) The climate policy of the EC - too hot to handle. 7) US climate

  15. The role of municipal public policies in oral health socioeconomic inequalities in Brazil: A multilevel study.

    Science.gov (United States)

    Aguiar, Violeta Rodrigues; Pattussi, Marcos Pascoal; Celeste, Roger Keller

    2017-12-07

    It is known that fluoridation has a contextual effect on oral health socioeconomic inequalities, but broad public policies have not been investigated. Thus, the aim of this study was to determine the effects of municipal public policies on oral health across different social strata. This was a cross-sectional study with 7328 12-year-old children and 5445 15-19-year-old adolescents from 177 Brazilian municipalities. Information at municipal level was collated for dental services, educational services, sanitation and water fluoridation. The main individual-level exposure was the disposable equivalent household income. The dichotomous outcomes were as follows: untreated dental caries (≥1 tooth), missing teeth (≥1 tooth) and filled teeth (≥1 tooth). Analyses were carried out using multilevel logistic regression. Interaction terms were tested between individual-level income and policy variables. The prevalence of untreated dental caries, missing and filled teeth was 47.0%, 15.1% and 47.5%, respectively. There was no significant interaction between income and policy indicators. Individuals living in municipalities with no water fluoridation had 1.42 (95% CI: 1.08-1.86) higher odds of having untreated dental caries; the odds ratio (OR) for those in municipalities with less education policies was 1.36 (95% CI: 1.07-1.73); those in municipalities with less sanitation had OR = 1.05 (95% CI: 0.78-1.40); and those in municipalities with less dental care had OR = 1.36 (95% CI: 1.02-1.80). Fluoridation and policies about sanitation, education and dental care were similarly associated with oral health in different social strata. Other policies on social and economic fields may be further explored. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  16. Climate policy studies by the Fridtjof Nansen Institute, ECON and Energy Data:10 Abstracts

    International Nuclear Information System (INIS)

    Andresen, S.; Eikeland, P.O.; Eleri, E.O.; Fermann, G.; Fredriksen, O.; Halseth, A.; Hansen, S.; Haugland, T.; Malnes, R.; Skjaerseth, J.B.; Ottosen, R.

    1993-01-01

    The overall focus is the relation between energy, environment and development on the national level and international co-operation concerning sustainable energy management and global environmental change. A series of country studies analyses the economic, political and institutional factors influencing energy, environment and climate policies. The role of non-state actors like NGOs and the energy industries in international environmental affairs is also closely examined. Strategies to enhance energy efficiency are studied with a particular focus on identifying and overcoming barriers to policy implementation. The ways in which developments in international energy markets affect the potential and scope of international environmental agreements are analysed, as are the impacts of different international environmental regimes on energy markets. Particular attention is paid on the opportunities and limitations of international institutions like the European Community, the United Nations, the multilateral development banks and GATT, in promoting international co-operation on energy and environmental issues. Strategies to overcome North/South conflicts over global environmental issues are examined, including issue linkages in international negotiations and North/South transfer of resources and technology. Another important area of sustainable production and consumption of energy in developing countries. Project titles are: 1) ''Leader'' and ''entrepreneur'' in international negotiations . A conceptual analysis. 2) Choosing climate policy. Decision theoretical premises. 3) Japan in the greenhouse responsibilities, policies and prospects for combating global warming. 4) Impacts on developing economies from changing trade regimes and growing international environmental concerns. 5) US energy policy in the greenhouse from the North slope forests to the Gulf Stream waters - this land was made for fossil fuels. 6) The climate policy of the EC - too hot to handle. 7) US climate

  17. A dawning demand for a new cannabis policy: A study of Swedish online drug discussions.

    Science.gov (United States)

    Månsson, Josefin

    2014-07-01

    This study examines how online discussions on drug policy are formulating an oppositional cannabis discourse in an otherwise prohibitionist country like Sweden. The focus of the paper is to identify demands for an alternative cannabis policy as well as analysing how these demands are linked to governance. The empirical material is 56 discussion-threads from the online message-board Flashback Forum that were active during the first eight months of 2012. Discourse theory was used to locate the discourse, and governmentality theory was used to locate the political belonging of the discourse. On Flashback Forum demands for a new cannabis policy are articulated in opposition to Swedish prohibitionist discourse. The oppositional discourse is constructed around the nodal points cannabis, harm, state and freedom that fill legalisation/decriminalisation/liberalisation with meaning. The nodal points are surrounded by policy demands that get their meaning through the particular nodal. These demands originate from neo-liberal and welfarist political rationalities. Neo-liberal and welfarist demands are mixed, and participants are simultaneously asking for state and individual approaches to handle the cannabis issue. Swedish online discourse on cannabis widens the scope beyond the confines of drug policy to broader demands such as social justice, individual choice and increased welfare. These demands are not essentially linked together and many are politically contradictory. This is also significant for the discourse; it is not hegemonised by a political ideology. The discourse is negotiated between the neo-liberal version of an alternative policy demanding individual freedom, and the welfarist version demanding social responsibility. This implies the influence of the heritage from the social-democratic discourse, centred on state responsibility, which have been dominating Swedish politics in modern times. Consequently, this study refutes that the demand for a new cannabis

  18. Climate policy studies by the Fridtjof Nansen Institute, ECON and Energy Data:10 Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    Andresen, S.; Eikeland, P.O.; Eleri, E.O.; Fermann, G.; Fredriksen, O.; Halseth, A.; Hansen, S.; Haugland, T.; Malnes, R.; Skjaerseth, J.B.; Ottosen, R

    1993-07-01

    The overall focus is the relation between energy, environment and development on the national level and international co-operation concerning sustainable energy management and global environmental change. A series of country studies analyses the economic, political and institutional factors influencing energy, environment and climate policies. The role of non-state actors like NGOs and the energy industries in international environmental affairs is also closely examined. Strategies to enhance energy efficiency are studied with a particular focus on identifying and overcoming barriers to policy implementation. The ways in which developments in international energy markets affect the potential and scope of international environmental agreements are analysed, as are the impacts of different international environmental regimes on energy markets. Particular attention is paid on the opportunities and limitations of international institutions like the European Community, the United Nations, the multilateral development banks and GATT, in promoting international co-operation on energy and environmental issues. Strategies to overcome North/South conflicts over global environmental issues are examined, including issue linkages in international negotiations and North/South transfer of resources and technology. Another important area of sustainable production and consumption of energy in developing countries. Project titles are: 1) ''Leader'' and ''entrepreneur'' in international negotiations . A conceptual analysis. 2) Choosing climate policy. Decision theoretical premises. 3) Japan in the greenhouse responsibilities, policies and prospects for combating global warming. 4) Impacts on developing economies from changing trade regimes and growing international environmental concerns. 5) US energy policy in the greenhouse from the North slope forests to the Gulf Stream waters - this land was made for fossil fuels. 6) The climate policy of

  19. Report of a Study of Ontario Medical School Admissions Policies and Practices, 1975.

    Science.gov (United States)

    Council of Ontario Universities, Toronto.

    Presented are the results of a study of admissions policies and practices in the five Ontario schools of medicine. The study consists of a review of published information and a detailed examination of 1975 statistics from the Ontario Medical School Application Service, supplemented by a series of interviews with medical school admissions officers,…

  20. Analysis of XFEL serial diffraction data from individual crystalline fibrils

    Directory of Open Access Journals (Sweden)

    David H. Wojtas

    2017-11-01

    Full Text Available Serial diffraction data collected at the Linac Coherent Light Source from crystalline amyloid fibrils delivered in a liquid jet show that the fibrils are well oriented in the jet. At low fibril concentrations, diffraction patterns are recorded from single fibrils; these patterns are weak and contain only a few reflections. Methods are developed for determining the orientation of patterns in reciprocal space and merging them in three dimensions. This allows the individual structure amplitudes to be calculated, thus overcoming the limitations of orientation and cylindrical averaging in conventional fibre diffraction analysis. The advantages of this technique should allow structural studies of fibrous systems in biology that are inaccessible using existing techniques.