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Sample records for performance haematology parameters

  1. Performance Evaluation and HaematologicalParameters of West ...

    African Journals Online (AJOL)

    Performance Evaluation and HaematologicalParameters of West African Dwarf Goats Fed Diet Containing Graded Level of Raw and Fermented Malted Sorghum ... influenced white blood cell count (WBC), lymphocytes, monocytes, basophil and mean corpuscular haemoglobin concentration across the dietary treatments.

  2. Effects of Pre and Probiotic on Growth Performance and Haematological Parameters in Pigs

    Directory of Open Access Journals (Sweden)

    Andrei Radu Szakacs

    2016-11-01

    Full Text Available The present study investigates the effects of dietary supplementation with feed supplements (prebiotics and probiotics on pig performance, the feed conversion ratio and some haematological parameters. The research was conducted on hybrid pigs [(Yorkshire × Landrace × Duroc] in a farm from Sălaj County, Romania. Pigs of 11 weeks (n = 200 were divided into 4 equal groups: a group fed with the probiotic, a prebiotic-fed group, a control group and a synbiotic (pre- and probiotic treated group. The control group was fed with a feed without the specified additives. Probiotic treated group was fed the same feedstuff but containing the additive Beta Plus® Ultra (Biochem( 5.12x1012 CFU / kg - Bacillus subtilis DSM 5750, 5.12x1012UFC / kg - Bacillus licheniformis (DSM 5749 and 921 g of betaine, in an amount of 1 kg / tonne of feed.  Prebiotic group had added to the feed an extract derived from the cell wall of Saccharomyces cerevisiae (TechnoMos® - Biochem in a dose of 250 g / ton of feed. The weight of 25 pigs in each compartment was recorded 9 times (over 85 days. Animal health was evaluated via clinical, haematological, and parasitological examinations. 5 rectal swabs were collected on day 11 and day 77 and faeces samples were taken in day 77 from each investigated group. Growth rate, feed consumption and some haematological parameters were measured. The body weight, average total weight gain and feed conversion rate increase by the dietary inclusion of the both pre and probiotic (p˃0.05. In the compartment treated with prebiotic the weight of the pigs has increased by 1030 g/day compared with 982 g/day value recorded in the control group. The average feed consumption was 3.21 kg/day in the control group while the group treated with prebiotic was only 2.99 kg/day. Feed conversion rate for all treated groups were lower than the one of control. Haematological parameters varied in physiological limits of species. Conclusion: These products show

  3. Changes in haematological parameters of Tilapia guineensis ...

    African Journals Online (AJOL)

    Changes in haematological parameters of Tilapia guineensis exposed to different concentrations of detergent under laboratory conditions. ... The experiment evaluated sub-lethal effect of the exposure on some haematological parameters including haemoglobin (Hb), red blood cell (RBC), packed cell volume (PCV), white ...

  4. Evaluation of Haematological and Biochemical Parameters of ...

    African Journals Online (AJOL)

    ADOWIE PERE

    Evaluation of Haematological and Biochemical Parameters of Juvenile Oreochromis niloticus after Exposure to Water Soluble Fractions of ... niloticus were evaluated. After a preliminary determination of the 96 h-LC50 of ... evaporation, dissolution, emulsion, photolysis and biodegradation which generate a water soluble.

  5. Effect of high wavelengths low intensity light during dark period on physical exercise performance, biochemical and haematological parameters of swimming rats.

    Science.gov (United States)

    Beck, W; Gobatto, C

    2016-03-01

    Nocturnal rodents should be assessed at an appropriate time of day, which leads to a challenge in identifying an adequate environmental light which allows animal visualisation without perturbing physiological homeostasis. Thus, we analysed the influence of high wavelength and low intensity light during dark period on physical exercise and biochemical and haematological parameters of nocturnal rats. We submitted 80 animals to an exhaustive exercise at individualised intensity under two different illuminations during dark period. Red light (> 600 nm; sports performance experiments.

  6. 10491 PERFORMANCE, CARCASS, HAEMATOLOGY AND BLOOD ...

    African Journals Online (AJOL)

    such studies is the health assessment impact of unconventional feedstuff ... investigate the performance, carcass, haematology and serum metabolites of hybro .... muscular work required to process these former diets which were relatively ...

  7. Comparative study of growth performance, meat quality and haematological parameters of Fayoumi, Rhode Island Red and their reciprocal crossbred chickens

    Directory of Open Access Journals (Sweden)

    Abida Parveen

    2012-04-01

    Full Text Available A total of 2001 unsexed day-old-chicks of each Fayoumi, Rhode Island Red (RIR, RIR × Fayoumi (RIFI and Fayoumi × RIR (FIRI were obtained from hatchery of Poultry Research Institute, Rawalpindi. The birds were maintained on deep litter system for a period of 20 weeks. The results revealed that the average day old weight was highest in RIR and FIRI, intermediate in RIFI and lowest in Fayoumi chickens. The RIR breed consumed more feed and gained maximum (P0.05 difference among pure and crossbred chickens. There was non-significant (P>0.05 difference in haematological values among all chickens. The total erythrocyte number, haemoglobin and packed cell volume increased with the advancement of age. However, erythrocyte sedimentation rate, mean corpuscular volume and mean corpuscular haemoglobin values decreased gradually with the advancement of age. It may be concluded that crossbred chickens gained better body weight than Fayoumi and moderate than RIR chickens with lower mortality. The crossbred chickens of FIRI showed better performance in all traits than crossbred chickens of RIFI.

  8. Haematological and Serum Bio-Chemical Parameters of West ...

    African Journals Online (AJOL)

    Haematological and Serum Bio-Chemical Parameters of West African Dwarf and Kalahari Red Goats in the Humid Tropics. ... Haematological results showed that white blood cell count, haemoglobin concentration, haematocrit, mean corpuscular volume, mean corpuscular haemoglobin and mean corpuscular haemoglobin ...

  9. Haematology, serum biochemistry and growth performance of ...

    African Journals Online (AJOL)

    High performing does have the tendency of producing healthy kids with reasonable weight at birth compared to least performing does. A study was conducted to investigate the haematology, serum biochemistry and growth performance of grazing pregnant Kalahari Red does fed concentrate diets at three protein levels.

  10. haematological parameters and serum biochemical indices of pre

    African Journals Online (AJOL)

    mrmrsolayiwola

    2012-05-01

    BWSFM) on haematological and serum biochemical parameters in rabbit were studied. Thirty-two (32) cross-bred. (New Zealand-white X Chinchilla) male weaner rabbits aged between 6 and 9 weeks were randomly.

  11. Haematological characteristics and performance of West African ...

    African Journals Online (AJOL)

    The effects of feeding crude petroleum contaminated forage on haematological characteristics and performance of 36 young West African Dwarf (WAD) goats was investigated in order to simulate the impact of real crude oil spillage on livestock and game. Graded levels (0.0, 1.5 and 3.0 g per kg forage) of stabilized “Bonny ...

  12. Beta-thalassaemia trait: haematological parameters

    International Nuclear Information System (INIS)

    Yousafzai, Y.M.; Khan, S.; Raziq, F.

    2010-01-01

    Thalassaemia syndromes are a group of hereditary disorders characterised by a genetic deficiency in the synthesis of --globin genes. The objective of this study was to determine the haematological features -thalassaemia trait (BTT), and to determine the sensitivity of Mean Corpuscular Volume (MCV), Mean Corpuscular Haemoglobin (MCH) and -thalassaemia trait. Methods: A descriptive study was conducted in Hayatabad Medical Complex, Peshawar from May 2009 to May 2010 with 203 subjects having BTT. Blood samples were collected in EDTA anti-coagulated tubes. RBC indices were taken as part of complete blood count (CBC) by haematology analyser, and Haemoglobin (Hb) electrophoresis was done to determine the HbA2 percentage. The data was collected and analyzed on statistical software for demographic details, RBC indices and HBA2 levels. Results: Out of 203 patients, 92 (45%) were males and 111 (55%) were females. Most patients tested were in the 15-45 year age group. One-hundred-sixty (79%) patients had anaemia. MCV was lower than 76 fl in all the cases. Mean MCV was 59.1 fl. MCH was low, the mean MCH being 19.3 g/dl. MCH <26 gave sensitivity of 99% in detecting BTT. We calculated MI for these cases and found out that it was <12 in 75% of cases and <15 in 197 (97%). Conclusion: Beta-thalassaemia traits present with a microcytic hypochromic blood picture, detected on simple haematology analysers as low MCV and MCH and MI which provide a beta- thalassaemia trait. (author)

  13. Comparison of conventional and organic management conditions on growth performance, carcass characteristics and haematological parameters in Karacabey Merino and Kivircik breeds.

    Science.gov (United States)

    Soysal, Deniz; Cibik, Recep; Aydin, Cenk; Ak, İbrahim

    2011-04-01

    Growth performance, carcass characteristics, post-slaughtering and haematological parameters of Kivircik and Karacabey Merino male lambs in conventional and organic management systems were compared. The animals which were weaned at 7 weeks of age were divided into Kivircik conventional, Kivircik organic (KO), Karacabey Merino conventional and Karacabey Merino organic (MO) groups containing 12 lambs each. Fattening was ended when lambs attained 35 kg of live weight. The time to attain the determined fattening weight was significantly different among the groups, and Merino lambs having higher live weight gain were earlier than Kivircik lambs (p < 0.05). Overall conventional (CG) and organic group lambs were also compared. Live weight gain, intra-abdominal fat amount, external fat thickness and visceral organ weight were significantly higher in CG lambs (p < 0.05). Higher haematocrit and erythrocyte counts were obtained with the CG group (p < 0.05), whilst triglyceride, total plasma cholesterol and lipoprotein (HDL, LDL, VLDL) levels between groups were not significant. Pneumonia was the unique infection, with an incidence of 50% (six lambs) and 16.6% (two lambs) for MO and KO animals, respectively. The mortality rate was 16.6% (two lambs) for MO group, whilst no mortality was recorded for KO group animals. The present study has shown that although Karacabey merino lambs had higher growth performance compared to Kivircik lambs, organically fattened lambs in whole exhibited inferior growth performance. Lower infection and mortality observed with Kivircik lambs suggested that they could be more resistant to infections and outdoor environmental conditions.

  14. The liability of some haematological parameters in chickens and ducks

    African Journals Online (AJOL)

    The liability of some haematological parameters in chickens and ducks. E.M. Smith, J Hattingh. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians ...

  15. Haematological and serum biochemical parameters of West African ...

    African Journals Online (AJOL)

    The study was conducted to evaluate the haematological and serum biochemical parameters of West African dwarf goats fed ensiled cassava leaves with molasses and caged layer waste. Eighteen West African dwarf goats were randomly assigned to three experimental diets consisting of cassava leaves ensiled alone ...

  16. Effects on haematological parameters and pathology of internal ...

    African Journals Online (AJOL)

    Effects on haematological parameters and pathology of internal organs of Trypanosoma brucei brucei infected albino rats. ... Group A served as the control (uninfected). ... The gross pathological effects on the internal organs showed significant enlargement of the spleen (splenomegaly) and slight enlargement of the liver ...

  17. studies on growth, organs weight and haematological parameters of ...

    African Journals Online (AJOL)

    user

    2012-06-01

    Jun 1, 2012 ... Maize which is the most available basal energy feedstuff is in constant demand for human and animal nutrition and for industrial processing (Esonu, 2000). The study was conducted to evaluate the effect of feeding graded level of cassava root meal flour on haematological and growth performance of broiler.

  18. The effect of continuous grouping of pigs in large groups on stress response and haematological parameters

    DEFF Research Database (Denmark)

    Damgaard, Birthe Marie; Studnitz, Merete; Jensen, Karin Hjelholt

    2009-01-01

    The consequences of an ‘all in-all out' static group of uniform age vs. a continuously dynamic group with litter introduction and exit every third week were examined with respect to stress response and haematological parameters in large groups of 60 pigs. The experiment included a total of 480 pigs...... from weaning at the age of 4 weeks to the age of 18 weeks after weaning. Limited differences were found in stress and haematological parameters between pigs in dynamic and static groups. The cortisol response to the stress test was increasing with the duration of the stress test in pigs from...... the dynamic group while it was decreasing in the static group. The health condition and the growth performance were reduced in the dynamic groups compared with the static groups. In the dynamic groups the haematological parameters indicated an activation of the immune system characterised by an increased...

  19. Effects of ginseng extract on various haematological parameters during aerobic exercise in the rat.

    Science.gov (United States)

    Ferrando, A; Vila, L; Voces, J A; Cabral, A C; Alvarez, A I; Prieto, J G

    1999-04-01

    The effects of the Ginseng extract on various biochemical and haematological parameters in male Wistar rats subjected to a treadmill exercise protocol were studied for 12 weeks. The results showed increases in the haematological parameters, these increases being greatest for the animals treated with the extract during the third month of the study. The exercise also led to increases in these parameters, while the combination of both exercise and extract produced smaller increases. This study shows a clear physiological response due to the ginseng extract administration that reproduces many of the effects obtained after long-term exercise. The combination of exercise and treatments seems to support the theory that there is no clear synergic effect when the advantages associated with the ingestion of ginseng are compared with the performance of exercise.

  20. Blood donor haematology parameters in two regions of Kenya ...

    African Journals Online (AJOL)

    Objectives: To determine the status of blood donor haematology in two regional sites in Kenya and to assess the potential role of automated haematology in National blood bank process control. Design: A cross sectional descriptive study. Setting: Two regional blood banks - Nairobi and its environs (Blood Transfusion ...

  1. Reference ranges of some haematological parameters in healthy ...

    African Journals Online (AJOL)

    Background: The haematological values of populations differ due to numerous factors. It is essential to establish the normal haematological values in every population to ensure appropriate interpretation of results in health and disease states. Materials and Methods: A total of 184 consenting apparently healthy adults (62 ...

  2. Performance and haematological indices of broiler chickens fed ...

    African Journals Online (AJOL)

    The effects of Azadirachta indica (neem), Spondias mombin and Chromolaena odorata leaf meals as natural feed supplements on performance and haematology of broilers were evaluated. Two hundred and sixty-four 1 day-old Arbor acre chicks were divided randomly into six treatments and four replicates. Treatment 1 ...

  3. Growth Performance, Haematological Indices and Cost Benefits of ...

    African Journals Online (AJOL)

    Lenovo pc

    Effect of replacing dietary maize with cassava peel meal (CPM) supplemented with Allzyme® SSF (SSF) on the growth performance, haematological indices and cost benefits of growing pigs was investigated. Chemical composition of CPM and diets used were determined using standard procedures. Twenty-four growing ...

  4. Laying performance, haematology and serum biochemical profile of ...

    African Journals Online (AJOL)

    The study was carried out to compare the effects of unfermented and fermented African locust bean on laying performance, haematology and serum biochemical profile of hens in a twelve week feeding trial. The unfermented African locust bean (UALB) contained seeds that were dehulled and boiled in water, without going ...

  5. Effect of Moringa oleifera leaf meal on haematological parameters ...

    African Journals Online (AJOL)

    Moringa oleifera leaf meal (MOLM) was included in broiler chickens' diets at graded levels of 0, 5, 10, 15, and 20% to make 5 treatments to assess haematology, serum biochemistry and haemagglutination potential in broiler chickens fed the experimental diets. The diets were formulated to be iso-caloric and isonitrogenous.

  6. Haematological and physiological parameters of West African dwarf ...

    African Journals Online (AJOL)

    Twenty four West African Dwarf (WAD) goats of both sexes (12 bucks and 12 does) raised under intensive system and weighing between 5 and 11 kg with different coat colours (Black, Brown, Tan and White) were used for this study to evaluate the effects of sex and coat colour on their haematological and physiological ...

  7. Effects on haematological parameters and pathology of internal ...

    African Journals Online (AJOL)

    Prof. Ogunji

    Key words: Trypanosoma, albino rat, haematology, pathology and blood ... women, men and children in 36 countries of sub-Sahara Africa suffer from Human ... and capacity for work due to the failure of livestock to utilize available food as ...

  8. Evaluation of growth performance, serum biochemistry and haematological parameters on broiler birds fed with raw and processed samples of Entada scandens, Canavalia gladiata and Canavalia ensiformis seed meal as an alternative protein source.

    Science.gov (United States)

    Sasipriya, Gopalakrishnan; Siddhuraju, Perumal

    2013-03-01

    The experiment was carried out to investigate the inclusion of underutilised legumes, Entada scandens, Canavalia gladiata and Canavalia ensiformis, seed meal in soybean-based diet in broilers. The utilisation of these wild legumes is limited by the presence of antinutrient compounds. Processing methods like soaking followed by autoclaving in sodium bicarbonate solution in E. scandens and C. gladiata and soaking followed by autoclaving in ash solution in C. ensiformis were adopted. The proximate composition of raw and processed samples of E. scandens, C. gladiata and C. ensiformis were determined. The protein content was enhanced in processed sample of E. scandens (46 %) and C. ensiformis (16 %). This processing method had reduced the maximum number of antinutrients such as tannins (10-100 %), trypsin inhibitor activity (99 %), chymotrypsin inhibitor activity (72-100 %), canavanine (60-62 %), amylase inhibitor activity (73-100 %), saponins (78-92 %), phytic acid (19-40 %) and lectins. Hence, the raw samples at 15 % and processed samples at 15 and 30 % were replaced with soybean protein in commercial broiler diet respectively. Birds fed with 30 % processed samples of E. scandens, C. gladiata and C. ensiformis showed significantly similar results of growth performance, carcass characteristics, organ weight, haematological parameters and serum biochemical parameters (cholesterol, protein, bilirubin, albumin, globulin and liver and kidney function parameters) without any adverse effects after 42 days of supplementation. The proper utilisation of these underutilised legumes may act as an alternative protein ingredient in poultry diets.

  9. Growth performance, haematological and biochemical study of ...

    African Journals Online (AJOL)

    A significant difference (P<0.05) was established in the growth parameters determined in the C. gariepinus fingerlings fed with the four frog formulations, namely, final weight, total weight, and mean feed gain, mean weight gain and feed conversion ratio The 40% R. galamensis ration elicited higher growth values than all ...

  10. laying performance, haematology and serum biochemical profile

    African Journals Online (AJOL)

    dehulled, boiled in water and made to undergo natural fermentation for 4 days. One hundred ... Improved performance traits, nitrogen retention ..... Tropical Legume Seeds in Diets of Exotic Meat- ... Protein binding capacity of microquantities of.

  11. Haematological characteristics and performance of West African ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-02-18

    Feb 18, 2009 ... ISSN 1684–5315 © 2009 Academic Journals. Full Length ... performance of 36 young West African Dwarf (WAD) goats was investigated in order to simulate the .... cause antibody depression, alter white blood cell counts,.

  12. Prolonged storage-induced changes in haematology parameters referred for testing

    Directory of Open Access Journals (Sweden)

    Elise Schapkaitz

    2015-08-01

    Full Text Available Background: Referral of samples for the work-up of haematological disorders from remote laboratories can result in a delay in analysis. Objective: The stability of the full blood count (FBC, differential count (DIFF, reticulocyte and peripheral blood smear (PBS morphology during extended storage was evaluated. Methods: Forty blood samples stored in ethylenediaminetetraacetic acid (EDTA were analysed on an ADVIA® 120 haematology analyser. The samples (25% abnormal; 75% normal were stored at room temperature (RT and at 4 °C – 8 °C. Analysis of samples stored at RT was performed every 12 hours for two days. Analysis of samples stored at 4 °C – 8 °C was performed at 12 hours and subsequently every 24 hours for seven days. Results: FBC parameters (red cell count, haemoglobin and DIFF parameters (percentages of basophils, lymphocytes and monocytes were stable for at least 48 hours when stored at RT. Platelets were only stable for 12 hours and the white cell count was stable for 36 hours when stored at RT. Storing samples at 4 °C – 8 °C significantly increased the stability of most parameters, in particular, mean cell volume and percentage of reticulocytes. However, DIFF parameters were associated with lower stability at 4 °C – 8 °C. PBS morphology was compromised prior to 12 hours whether stored at RT or at 4 °C – 8 °C. Conclusion: This study provides evidence that blood samples stored in EDTA at 4 °C – 8 °C for seven days are suitable for testing on the ADVIA® 120 analyser for the FBC and percentage of reticulocyte parameters. However, storage at 4 °C – 8 °C is not a solution for samples referred for DIFF and PBS morphology review.

  13. Nutritive value, growth performance and haematological parameters ...

    African Journals Online (AJOL)

    Twelve West African dwarf sheep, aged between 6 to 8 months and weighing 9 to 10.5 kg were randomly allocated to four treatments consisting of ensiled pineapple fruit waste and cassava root meal (CRM+PFW); sun-dried pineapple fruit waste (PFW); ensiled cassava peels and pineapple fruit waste (CP+PFW); cassava ...

  14. Effects of Photoperiod on the Haematological Parameters of Clarias Gariepinus Fingerlings Reared in Water Recirculatory System

    Directory of Open Access Journals (Sweden)

    Solomon S.G.

    2012-08-01

    Full Text Available Haematological analyses has been routinely used in determining the physiological state of animals and known to be affected by different environmental factors, the present study was therefore designed to assess the effect of 24 hours of light (00D: 24L, 24 hours of darkness (24D: 00L and 12 hour light / 12 hours darkness (12D: 12L photoperiod on the haematological parameters of the African Catfish. At the end of the six weeks experiment, it was observed that some haematological parameters such as Mean Corpuscular Haemoglobin Concentration (MCHC, the Mean White Blood Cells (WBC, Mean Red Blood Cells (RBC, Haemoglobin content (HGB, Platelet count (PLT showed significant difference (P0.05. However MCHC and MCH were noticed to increase as the light period increased while the other parameters reduced as the light period increased. The findings indicate that exposure of the African Catfish to continuous light for six weeks duration elicits response in the haematological profile of the fish.

  15. Transfusion treatment impact in the improvement of haematological parameters in patients with gastrointestinal bleeding

    OpenAIRE

    Iliriane Bunjaku; Mimoza Zhubi; Bukurije Zhubi; Emrush Kryeziu; Sadik Zeka

    2012-01-01

    Introduction: Transfusion treatment (TT) is necessary in patients with gastrointestinal bleeding (GIB) for lost blood substitution. This study was aimed at assessing the changes in haematological parameters  (hemoglobin, hematocrit, red blood cell count, white cell count, platelet count and prothrombin time) before and after TT in anaemic patients with GIB in order to analyse the effect of this treatment.Methods: There have been included 293 patients with GIB (the average age was 57.3, ranged...

  16. Effect of genotype on haematology and biochemical parameters of ...

    African Journals Online (AJOL)

    Frizzle n = 33, Naked neck, n= 33 and Normal n = 33) were generated from 36 matured local chickens and used for the study to determine the effect of genotype on hematological and biochemical parameters of local chicken in the humid ...

  17. haematological parameters and serum biochemical indices of pre

    African Journals Online (AJOL)

    mrmrsolayiwola

    2012-05-01

    May 1, 2012 ... pubertal male rabbits fed with graded level of blood- ... The effects of feeding graded levels of blood wild sunflower forage meal ... and serum biochemical parameters in rabbit were studied. ... (Cheeke et al., 1986), high in protein, low in cholesterol ..... assay of nutritional anaemia (dietary deficiency of iron,.

  18. Haematological and Biochemical Parameters during the Laying Period in Common Pheasant Hens Housed in Enhanced Cages

    Directory of Open Access Journals (Sweden)

    Petra Hrabčáková

    2014-01-01

    Full Text Available The development of selected haematological and biochemical parameters during the laying period was monitored in common pheasant hens housed in an enhanced cage system. The cages were enhanced by the addition of two perches and a shelter formed by strips of cloth hanging in the corner of the cage. The results showed significant changes in the haematological and biochemical parameters monitored during egg laying. At the time when laying capacity approached a maximum, a decrease was observed (P<0.05 in haematocrit, erythrocytes, and haemoglobin values, whereas monocytes, eosinophils, the heterophil/lymphocyte ratio, phosphorus, and calcium exhibited an increase (P<0.05. At the end of the laying period, an increase (P<0.05 was recorded in the count of leukocytes, heterophils, lymphocytes and basophils, the heterophil to lymphocyte ratio, and the concentrations of aspartate aminotransferase, cholesterol, phosphorus, and calcium, whereas lower values (P<0.05 were recorded for haematocrit and plasma total protein in comparison with the values of the indicators at the beginning of the laying period. The results provide new information about dynamic changes in selected haematological and biochemical parameters in clinically healthy common pheasant hens during the laying period.

  19. Glutathione Enhancer Protects Some Biochemical and Haematological Parameters from the Effect of Electromagnetic Field

    International Nuclear Information System (INIS)

    Marzook, E.A.; Marzook, F.A.

    2016-01-01

    The Present study was designed to study the effect of exposure to electromagnetic field (EMF), emitted from a cellular tower for mobile phone on some biochemical and haematological parameters in male albino rats and to evaluate of the possible protective role of the antioxidant glutathione enhancer on the studied parameters. Three groups of rats were studied, the control (unexposed), the exposed and the treated exposed groups. Exposed groups were subjected to EMF at frequency of 900 MHz, with a peak power of about 60 W, power density of 0.05 mW/ cm"2 at the site of exposure for 24 h/ day for 8 weeks, at the same time treated group was supplied with oral injection of glutathione enhancer three times weekly. At the end of experiment, serum levels of thyroid stimulating hormone (TSH), calcium (Ca), uric acid, malondialdehyde (MDA) beside, the activity of lactate dehydrogenase (LDH) were measured also, some haematological parameters were estimated. Impairment of TSH and serum calcium was expressed by a decrease in serum levels of the exposed group. Meanwhile, serum level of MDA, uric acid and the activity of LDH were increased by exposure. The haematological studies revealed that, exposure to electromagnetic spectrum induced significant reduction in red blood cell counts (RBC's), and haemoglobin concentration (Hb), meanwhile reticulocyte count (Ret) was elevated. The leucocyte counts (WBC's) and platelets count were not affected by exposure. The study demonstrated that glutathione enhancer can attenuate the side effects of exposure to electromagnetic field.

  20. Effect of ellagic acid on some haematological, immunological and antioxidant parameters of rainbow trout (Oncorhynchus mykiss).

    Science.gov (United States)

    Mişe Yonar, S; Yonar, M E; Yöntürk, Y; Pala, A

    2014-10-01

    In this study, effect of ellagic acid on some haematological, immunological and antioxidant parameters in the blood and various tissues of rainbow trout (Oncorhynchus mykiss) were examined. Four groups of rainbow trout were fed experimental diets containing either no ellagic acid (control) or supplemented with ellagic acid at 50 mg/kg diet (EA-50), 100 mg/kg diet (EA-100) or 150 mg/kg diet (EA-150) for 21 days. Samples of the blood and tissue (liver, kidney and spleen) were collected at the end of the experiment and analysed for their haematological profile (the red blood cell count, the haemoglobin concentration and the haematocrit level), immune response (the white blood cell count, the oxidative radical production (NBT activity), the total plasma protein and total immunoglobulin level) and oxidant/antioxidant status (the malondialdehyde level, the superoxide dismutase, catalase and glutathione peroxidase activity as well as the reduced glutathione concentration). The findings of this study demonstrated that ellagic acid had a positive effect on the haematological parameters, the immune response and the antioxidant enzyme activities of the fish. Journal of Animal Physiology and Animal Nutrition © 2014 Blackwell Verlag GmbH.

  1. Communication during haematological consultations; patients' preferences and professionals' performances.

    NARCIS (Netherlands)

    Bruinessen, I.R. van; Hout, L.E. van der; Weel-Baumgarten, E.M. van; Gouw, H.; Zijlstra, J.M.; Dulmen, S. van

    2016-01-01

    Many patients with haematological malignancies experience barriers in clinical communication. Reaching effective communication is of great importance as it has been linked to a range of improved patient outcomes such as satisfaction, compliance to treatment, perceived quality of life and physical

  2. Communication during haematological consultations; patients' preferences and professionals' performances

    NARCIS (Netherlands)

    Bruinessen, I.R. van; Hout, L.E. van der; Weel-Baumgarten, E.M. van; Gouw, H.; Zijlstra, J.M.; Dulmen, A.M. van

    2016-01-01

    Many patients with haematological malignancies experience barriers in clinical communication. Reaching effective communication is of great importance as it has been linked to a range of improved patient outcomes such as satisfaction, compliance to treatment, perceived quality of life and physical

  3. Haematology and Serum Biochemistry Parameters and Variations in the Eurasian Beaver (Castor fiber).

    Science.gov (United States)

    Girling, Simon J; Campbell-Palmer, Roisin; Pizzi, Romain; Fraser, Mary A; Cracknell, Jonathan; Arnemo, Jon; Rosell, Frank

    2015-01-01

    Haematology parameters (N = 24) and serum biochemistry parameters (N = 35) were determined for wild Eurasian beavers (Castor fiber), between 6 months - 12 years old. Of the population tested in this study, N = 18 Eurasian beavers were from Norway and N = 17 originating from Bavaria but now living extensively in a reserve in England. All blood samples were collected from beavers via the ventral tail vein. All beavers were chemically restrained using inhalant isoflurane in 100% oxygen prior to blood sampling. Results were determined for haematological and serum biochemical parameters for the species and were compared between the two different populations with differences in means estimated and significant differences being noted. Standard blood parameters for the Eurasian beaver were determined and their ranges characterised using percentiles. Whilst the majority of blood parameters between the two populations showed no significant variation, haemoglobin, packed cell volume, mean cell haemoglobin and white blood cell counts showed significantly greater values (pbeavers or between sexually immature (beavers in the animals sampled. With Eurasian beaver reintroduction encouraged by legislation throughout Europe, knowledge of baseline blood values for the species and any variations therein is essential when assessing their health and welfare and the success or failure of any reintroduction program. This is the first study to produce base-line blood values and their variations for the Eurasian beaver.

  4. Effect of Fractionated Low Doses of Gamma Radiation on Some Haematological and Immunological Parameters in Albino Rat

    International Nuclear Information System (INIS)

    Bahgat, M.M.; Abdel-Khalek, L.G.

    2003-01-01

    This study was performed on 30 mature male albino rats to evaluate the direct effect of fractionated low doses (0.5 Gy twice weekly) gamma radiation and delayed effect (one month post-irradiation) on some haematological and immunological parameters. The rats were divided into three equal groups, Control and two whole body gamma-irradiated groups the irradiated groups were subjected to total doses of 4 and 8 Grays over a period of one and two months, respectively. The blood samples and peritoneal macrophages were taken twice from each irradiated rats at the end of their irradiation period and after one month post irradiation. Activated peritoneal macrophages in all groups showed significant decrease as compared to control group denoting that irradiation may cause receptor alteration and/or decrease in the phagocytic power of macrophages lasting for a longer time. Throughout the whole experiment there was wide variation in platelet count with no significant or minimal changes in other blood elements. Moreover, in the post irradiation group after two months irradiation, all the haematological parameters tested, except the Hct, were increased as compared to the control group. These results pointed to that the bone marrow and lymphoid organs of the animals can tolerate fractionated low dose irradiation through rapid recovery and/or compensatory stimulation. The presence of many target cells in the post irradiated group increases the red blood cell fragility

  5. The effect of Iron Supplying on VO2 MAX and Haematology Parameter on Menstrual Woman

    Science.gov (United States)

    Nailuvar Sinaga, Rika; Sari Harahap, Novita; Mediyana Sari, Rima

    2018-03-01

    One of the supporting factors to have good aerobic endurance requires high VO2 max levels supported by good quality and quantity level of Haematology parameter especially such as erythrocytes, hematocrit and hemoglobin. One of the components in hemoglobin is iron which functions as theoxygen transport to parts of all body required in the process of metabolism. The objective of this research was to find out the difference between VO2 Max and Haematology parameter between iron supplying and no iron supplyingonmenstrual woman. The type of this research is quasi experimental research with non-randomized control group Pretest-Postest Design. The subjectsarethe studentsat faculty of Sports Sciences, Medan State University with the criteria of female gender, monthly regular menstrual cycle, having the level of health and the level of training, willing to be a sample by filling out informed consent. The total number of research subjectsis twenty students, divided into two groups namely the treatment group and the control group. The hematology parameter was measuredby Haemotology analyzer and VO2 Max was measured by multi-stage run. The result showed that there was a significant effect of iron supplyingon the increase of erythrocyte level on menstrual women, hemotocrit, haemoglobin and an increase in VO2 Max. Iron supplying on menstrual woman has the effect on the increase of erythrocyte, hematocrit, hemoglobin level and VO2 Max

  6. Innovative haematological parameters for early diagnosis of sepsis in adult patients admitted in intensive care unit.

    Science.gov (United States)

    Buoro, Sabrina; Manenti, Barbara; Seghezzi, Michela; Dominoni, Paola; Barbui, Tiziano; Ghirardi, Arianna; Carobbio, Alessandra; Marchesi, Gianmariano; Riva, Ivano; Nasi, Alessandra; Ottomano, Cosimo; Lippi, Giuseppe

    2018-04-01

    This study was aimed to investigate the role of erythrocyte, platelet and reticulocyte (RET) parameters, measured by new haematological analyser Sysmex XN and C reactive protein (CRP), for early diagnosis of sepsis during intensive care unit (ICU) stay. The study population consisted of 62 ICU patients, 21 of whom developed sepsis during ICU stay and 41 who did not. The performance for early diagnosing of sepsis was calculated as area under the curve (AUC) of receiver operating characteristics curves analysis. Compared with CRP (AUC 0.81), immature platelet fraction (IPF) (AUC 0.82) showed comparable efficiency for identifying the onset of sepsis. The association with the risk of developing sepsis during ICU stay was also assessed. One day before the onset of sepsis, a decreased of RET% was significantly associated with the risk of developing sepsis (OR=0.35, 95% CI 0.14 to 0.87), whereas an increased of IPF absolute value (IPF#) was significantly associated with the risk of developing sepsis (OR=1.13, 95% CI 1.03 to 1.24) 2 days before the onset of sepsis. The value of CRP was not predictive of sepsis at either time points. IPF# and RET% may provide valuable clinical information for predicting the risk of developing sepsis, thus allowing early management of patients before the onset of clinically evident systemic infections. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  7. Analysis Of Clinical, Haematological And Biochemical Parameters In Patients With Infectious Mononucleosis

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    Canović Petar

    2015-12-01

    Full Text Available Primary infection with Epstein-Barr virus (EBV usually occurs in early childhood and often does not present clinical symptoms. More than 90% of adults are infected with this virus. A primary infection that occurs in adolescence or adulthood is usually clinically presented as infectious mononucleosis with a triad of symptoms: fever, lymphadenopathy and pharyngitis. Our retrospective study included 51 patients with a median age of 17 (9-23 years and serologically confirmed infectious mononucleosis. All patients with infectious mononucleosis were treated at the Clinic for Infectious Diseases at the Clinical Center in Kragujevac during 2013. We analysed the clinical, haematological and laboratory parameters of patients. The aspartate-aminotransferase levels were increased in 40 patients, with a mean value of 116.24 (±93.22; the alanine-aminotransferase levels were increased in 44 patients, with a mean value of 189.24 (±196.69. Lymphadenopathy was the most common clinical feature upon admission in 49 patients (96%; 38 patients (74.5% had splenomegaly, and 20 (39% had hepatomegaly. Twenty-six patients (51% had leukocytosis with lymphocytosis, while 15 (75% of the 20 who had a normal leukocyte count also had lymphocytosis. In the present study, we updated the clinical, haematological and laboratory parameters, which may lead to the establishment of an accurate diagnosis and promote further treatment of the patients.

  8. Effects of Malathion Acute Toxicity on Behavioral and Haematological Parameters in Capoeta damascina (Cypriniformes: Cyprinidae

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    Saeed Shahbazi

    2015-07-01

    Full Text Available   The present study investigated the effects of acute toxicity of malathion on behavioral and haematological parameters in the cyprinid Capoeta damascina. The specimens were collected from the Kordan River, Karaj, Iran in August, 2014 and were exposed to different concentrations of malathion at the laboratory (24, 48, 72 mg L‑1 based on 96h-LC (10; 30; 50; 90 which was 6.08 (5.22-7.18 mg L-1. The animals were then exposed to 0.76, 1.00 and 1.52 mg L-1 of malathion for 10 days. Blood samples were collected in days 1, 5 and 10. Red blood cell (RBC, white blood cell (WBC, hemoglobin (Hb, hematocrit (PVC, mean corpuscular volume (MCV, mean corpuscular hemoglobin (MCH, and mean corpuscular hemoglobin concentration (MCHC were measured. Behavioral abnormalities were observed in fishes exposed to high levels of malathion. The specimens exposed to malathion had significantly lower RBC, WBC, Hb, PVC but higher MCV and MCH than those of the control group. No significant difference was detected in MCHC the exposed and control specimens. Hematological parameters (except MCHC were significantly correlated with exposure time. In conclusion, malathion showed extensive haematological effects on C. damascina that might be used as bioindicator of this pesticide in flowing waters.  

  9. Population based reference intervals for common blood haematological and biochemical parameters in the akuapem north district.

    Science.gov (United States)

    Koram, Ka; Addae, Mm; Ocran, Jc; Adu-Amankwah, S; Rogers, Wo; Nkrumah, Fk

    2007-12-01

    To estimate the reference intervals for commonly used blood haematology and biochemical parameters in an adult (18-55yrs) population of residents of Mampong Akuapem. This was a population based cross sectional study of a randomly selected sample of the adult population of Mampong. The sample was selected from an updated census list of the Mampong area. Median values (95% range) for measured parameters were established as follows: Haemoglobin, (males) 14.2 g/dl (females) 12.0 g/dl Alanine aminotransferase (ALT), (female) 19.6 U/L (males) 26.1 U/L and Creatinine, (males) 108 mmol/L (females) 93 mmol/L. In comparison to reference values that are commonly used in Ghana, the haemoglobulin levels from this study were lower, and liver function parameters higher. This could be a result of genetic or environmental differences and calls for the need to establish site specific reference values applicable to our population.

  10. Effects of bifenthrin on some haematological, biochemical and histopathological parameters of common carp (Cyprinus carpio L.).

    Science.gov (United States)

    Velisek, J; Svobodova, Z; Machova, J

    2009-11-01

    The aim of this study was to assess the effect of bifenthrin on common carp (Cyprinus carpio L.). The 96-h LC50 value of Talstar EC 10 (active substance 100 g l(-1) bifenthrin) was found to be 57.5 microg l(-1). Examination of haematological and biochemical profiles and histological tissue examination was performed on common carp after 96 h of exposure to Talstar EC 10 (57.5 microg l(-1)). The experimental group showed significantly higher (P bifenthrin-based Talstar EC 10 pesticide preparation was classified as a substance strongly toxic for fish.

  11. Haematology and Serum Biochemistry Parameters and Variations in the Eurasian Beaver (Castor fiber.

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    Simon J Girling

    Full Text Available Haematology parameters (N = 24 and serum biochemistry parameters (N = 35 were determined for wild Eurasian beavers (Castor fiber, between 6 months - 12 years old. Of the population tested in this study, N = 18 Eurasian beavers were from Norway and N = 17 originating from Bavaria but now living extensively in a reserve in England. All blood samples were collected from beavers via the ventral tail vein. All beavers were chemically restrained using inhalant isoflurane in 100% oxygen prior to blood sampling. Results were determined for haematological and serum biochemical parameters for the species and were compared between the two different populations with differences in means estimated and significant differences being noted. Standard blood parameters for the Eurasian beaver were determined and their ranges characterised using percentiles. Whilst the majority of blood parameters between the two populations showed no significant variation, haemoglobin, packed cell volume, mean cell haemoglobin and white blood cell counts showed significantly greater values (p<0.01 in the Bavarian origin population than the Norwegian; neutrophil counts, alpha 2 globulins, cholesterol, sodium: potassium ratios and phosphorus levels showed significantly (p<0.05 greater values in Bavarian versus Norwegian; and potassium, bile acids, gamma globulins, urea, creatinine and total calcium values levels showed significantly (p<0.05 greater values in Norwegian versus Bavarian relict populations. No significant differences were noted between male and female beavers or between sexually immature (<3 years old and sexually mature (≥3 years old beavers in the animals sampled. With Eurasian beaver reintroduction encouraged by legislation throughout Europe, knowledge of baseline blood values for the species and any variations therein is essential when assessing their health and welfare and the success or failure of any reintroduction program. This is the first study to produce

  12. EVALUATION OF ANAEMIA USING RED CELL AND RETICULOCYTE PARAMETERS USING AUTOMATED HAEMATOLOGY ANALYSER

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    Vidyadhar Rao

    2016-06-01

    Full Text Available Use of current models of Automated Haematology Analysers help in calculating the haemoglobin contents of the mature Red cells, Reticulocytes and percentages of Microcytic and hypochromic Red cells. This has helped the clinician in reaching early diagnosis and management of Different haemopoietic disorders like Iron Deficiency Anaemia, Thalassaemia and anaemia of chronic diseases. AIM This study is conducted using an Automated Haematology Analyser to evaluate anaemia using the Red Cell and Reticulocyte parameters. Three types of anaemia were evaluated; iron deficiency anaemia, anaemia of long duration and anaemia associated with chronic disease and Iron deficiency. MATERIALS AND METHODS The blood samples were collected from 287 adult patients with anaemia differentiated depending upon their iron status, haemoglobinopathies and inflammatory activity. Iron deficiency anaemia (n=132, anaemia of long duration (ACD, (n=97 and anaemia associated with chronic disease with iron deficiency (ACD Combi, (n=58. Microcytic Red cells, hypochromic red cells percentage and levels of haemoglobin in reticulocytes and matured RBCs were calculated. The accuracy of the parameters was analysed using receiver operating characteristic analyser to differentiate between the types of anaemia. OBSERVATIONS AND RESULTS There was no difference in parameters between the iron deficiency group or anaemia associated with chronic disease and iron deficiency. The hypochromic red cells percentage was the best parameter in differentiating anaemia of chronic disease with or without absolute iron deficiency with a sensitivity of 72.7% and a specificity of 70.4%. CONCLUSIONS The parameters of red cells and reticulocytes were of reasonably good indicators in differentiating the absolute iron deficiency anaemia with chronic disease.

  13. Growth performance, haematology and cost benefit of growing rabbits reared on different feed access times and restriction durations

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    Obasa, O.A

    2016-06-01

    Full Text Available Sixty growing rabbits of mixed breeds and sexes were used for 10 wk in a 4 x 3 factorial experimental design to test for the effect of different feed access times (2, 4, 6 and 24 h and different restriction durations (2, 4 and 6 wk on the performance, haematological parameters and cost benefits of growing rabbits. Data obtained were subject to a 2�way analysis of variance. Results showed significantly higher (p0.05 across the feed access time and restriction duration. White blood cell was higher in growing rabbits on 2-h feed access time for 6-wk duration of restriction while all other parameters measured for haematology were not significantly affected by the feed access time and restriction duration. Total cost of feed consumed was highest in growing rabbits maintained on 24-h feed access time. Cost of feed per kg weight gain was not significantly influenced across the feed access times and the restriction durations. It was concluded that for a reduced cost of feeding without an adverse effect on the performance and haematological profile, growing rabbits should be raised on not less than 4-h feed access time for 2-wk restriction duration.

  14. Biochemical and Haematological Blood Parameters at Different Stages of Lactation in Cows

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    Cristian Ovidiu COROIAN

    2017-05-01

    Full Text Available The health status of cows is evaluated and depending on haematological and biochemical profile of blood. Nutrition is the main technological factor that can produce profound changes in the metabolic profile in animals (Dhiman et al., 1991; Khaled et al., 1999; Ingvartsen, 2006. Blood parameters analyze can lead to identify if there are errors in nutrition of lactating cows (Payne et al., 1970. The aim of this study was the evaluation of metabolic and biochemical changes that occur during colostrum period and in terms of number of lactations in cows. The biological material was represented by a total of 60 heads of dairy cows from a family farm from Sălaj County, Romania. The cows are all from Holstein breed and presented no clinical signs of any specific pathology. Blood samples were collected from the jugular vein of each cow and analyzed. 10 individuals from each of the six lactations have been randomly selected. Haematological and biochemical parameters showed variations depending on factors analyzed here. In lactation 1 Hb was 7.55±3.05 (g/dl, while in lactation 6 the value was 12.5±2.10 (g/dl. RBC ranged as follows: in lactation 1 - 28.50±2.05 and in lactation 6 - 30.02±2.05. Lymphocytes varied within very wide limits under the influence of lactation: in lactation 1 - 2.8±1.56 and in lactation 6 - 7.55±1.80. The number of lactations and lactation rank have influenced blood biochemical and hematological parameters in dairy cows. Biochemical parameters are influenced by post-partum day, showing the lowest values in the early days of colostral period and the highest in the last few days of the same period.

  15. Who are the support persons of haematological cancer survivors and how is their performance perceived?

    Science.gov (United States)

    Hall, Alix; Lynagh, Marita; Carey, Mariko; Sanson-Fisher, Rob; Mansfield, Elise

    2017-12-01

    To explore: (1) how haematological cancer survivors and their support persons perceive the overall performance of the support person; (2) disagreement between survivor and support person ratings; and (3) characteristics associated with support persons rating their performance poorly. This is a substudy of a larger project of Australian haematological cancer survivors and their support persons. For this substudy, haematological cancer survivors were recruited from 4 Australian population-based cancer registries and asked to pass on a questionnaire package to their support persons. Survivors who passed on a questionnaire package to their support person were asked to answer questions about the support person and how they perceived the support person's performance. Similarly, support persons answered questions on their own performance as a support person. A total of 924 haematological cancer survivors and 821 support persons were eligible for this study. Most survivors rated their support person as performing very well (84%) while less than half (48%) of support persons rated their own performance as very well. There was significant disagreement between survivor and their support person (dyad) ratings of the support person's performance. Support persons with above normal levels of depression (vs those with normal levels) had significantly higher odds of rating their own performance as "not well/somewhat well." Health care providers should consider providing additional education and skills-based interventions to support persons who experience increased symptoms of depression. Copyright © 2017 John Wiley & Sons, Ltd.

  16. The effect of vitamin B12 and folic acid supplementation on routine haematological parameters in older people

    NARCIS (Netherlands)

    Smelt, Antonia F.H.; Gussekloo, Jacobijn; Bermingham, Lynette W.; Allen, Elizabeth; Dangour, Alan D.; Eussen, Simone J.P.M.; Favrat, Bernard; Groot, de Lisette C.P.G.M.; Kok, Frans J.; Kwok, Timothy; Mangoni, Arduino A.; Ntaios, George; Rest, van de Ondine; Seal, Eric; Vaucher, Paul; Verhoef, Petra; Stijnen, Theo; Elzen, Den Wendy P.J.

    2018-01-01

    Background/objectives: Low vitamin B12 and folate levels in community-dwelling older people are usually corrected with supplements. However, the effect of this supplementation on haematological parameters in older persons is not known. Therefore, we executed a systematic review and individual

  17. Relationship between anthropometric and haematological ...

    African Journals Online (AJOL)

    Relationship between anthropometric and haematological parameters among third trimester pregnant women in Sokoto State, Northwest Nigeria. ... access to good healthcare so that the ideal anthropometric and haematological parameters can be achieved during pregnancy to guarantee good feto-maternal outcome.

  18. Haematological parameters in different african populations: an experience from united nations level 3 hospital

    International Nuclear Information System (INIS)

    Iftikhar, R.; Khan, N.U.; Iqbal, Z.; Anwar, M.I.

    2017-01-01

    To evaluate hematological parameters in African population to estimate normal reference intervals for these tests. Study Design: Cross sectional observational study. Place and Duration of Study: Department of Pathology, United Nations level 3 hospital, Nyala, Darfur from 1st Mar to 30th Dec 2014. Material and Methods: There were 396 healthy African male and female volunteers selected between 18-65 years of age, belonging to different countries. Fresh whole blood was used to measure haemoglobin (Hb) concentration, haematocrit (Hct), total red blood cell (TRBC) count, mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), platelet count, total leucocyte count (TLC) and differential white blood cells count. Data were analysed using SPSS version 19. Results: Mean Hb of study group was 13.81 +- 1.99 g/dl. Mean TLC was 5.50 +- 1.96 x 103/ul. Mean lymphocyte count was 2.58 +- 0.95. Mean platelet count was 234 +- 92 x103 /ul. Mean values for Hb Concentration, TRBC, Hct Ratio, MCV, MCH and MCHC were all higher for African Males than Females; this difference was statistically significant (p<0.05). Conclusion: This multi-national African population based study confirms the variations in haematological parameters previously described in single nation African studies. The commonly observed variations in normal adults are low RBC indices, relative neutropenia and lymphocytosis. (author)

  19. Role of platelet parameters and haematological indices in myocardial infarction and unstable angina

    International Nuclear Information System (INIS)

    Yaghoubi, A.; Golmohamadi, Z.; Alizadehasi, A.; Azarfarin, R.

    2013-01-01

    Objective: To explore the significance of platelet parameters, including mean platelet volume, platelet count and other haematological indices, in patients of acute coronary syndrome. Methods: In this one-year retrospective cross-sectional study in 2010, a total of 631 patients were enrolled at the Cardiovascular Research Institute, Tabriz University of Medical Sciences, Iran, and classified into three groups: myocardial infarction, unstable angina, and Control. Cardiovascular risk factors such as smoking, diabetes mellitus, hyperlipidaemia and hypertension status were compared. Blood samples were collected for the measurement of platelet count, mean platelet volume and other haematological indices, including prothrombin time, partial thromoplastin time, blood group and Rh, haematocrit, haemoglobin, and erythrocyte sedimentation rate. SPSS 18 was used for statistical analysis. Results: Of the total, there were 210 (33.3%; 163 men, 47 women) with myocardial infarction whose mean age was 62.7+-14.2 years; 211 (33.3%; 110 men, 101 women) had unstable angina with a mean age of 63.5+-13.1 years and 210 (33.3%; 117 men, 90 women) health controls with a mean age of 60.6+-12.8 years. The mean platelet volume values of patients in the first two groups were significantly higher than the control group (10.14 +-1.05 fL, 9.82 +- 0.93 fL and 9.34+-1.14 fL, respectively; p< 0.001). The platelet count was detected to be significantly lower in the patients than the controls (207.92+-58.40*109/L, 220.18+-65.81*109/L, 238+-56.10*109/L, respectively, p<0.001). While blood cell count was significantly higher in those with myocardial infarction compared to the unstable angina patients and control group (P<0.001). Differences in mean values of mean platelet volume between the two patient groups was not significant, but mean values of platelet count was statistically significant between these two groups (p<0.04). Conclusion: Mean platelet volume and platelet count may be considered

  20. Impact of supplementing diets with propolis on productive performance, egg quality traits and some haematological variables of laying hens.

    Science.gov (United States)

    Abdel-Kareem, A A A; El-Sheikh, T M

    2017-06-01

    One hundred and twenty eight, 28-weeks-old Lohmann LSL hybrid layers were used in this experiment, which lasted 12 weeks to investigate the effect of propolis supplementation on the productive performance, egg quality traits and haematological variables of laying hens. All hens were randomly classified into four equal experimental groups, eight replicates (4 birds/each). Hens in group 1 were fed on a commercial diet and considered as control group, while those in groups 2, 3 and 4 were fed on the same commercial diet and supplemented with 250, 500 and 1000 mg propolis/kg diet. The obtained results revealed that daily feed consumption/hen increased insignificantly with increasing propolis level than that of the control group. Regarding the means of egg mass and egg production rate, it was observed that the laying hens fed diets containing 250 and 1000 mg propolis/kg significantly (p hens as compared to those in the control. Concerning the haematological parameters, the results showed that the levels of total protein and globulin increased significantly with increasing propolis level, while cholesterol and liver enzymes were significantly decreased (p hens in the treated groups significantly decreased, whereas the lymphocyte count significantly increased, resulting in a decreased H/L ratio than that of the control group. Thus, it could be concluded that the supplementation of 250 mg propolis/kg diet is highly recommended to improving egg production, blood constituent and haematological parameters of the commercial laying hens. Journal of Animal Physiology and Animal Nutrition © 2015 Blackwell Verlag GmbH.

  1. EFFECT OF DEOXYNIVALENOL ON SOME HAEMATOLOGICAL, BIOCHEMICAL AND ANTIOXIDANT PARAMETERS OF PORCINE BLOOD IN VITRO

    Directory of Open Access Journals (Sweden)

    Katarína Zbyňovská

    2013-02-01

    Full Text Available The most important and the most common Fusarium mycotoxin is deoxynivalenol (DON. It occurs predominantly in grains such as wheat, barley, and maize and less often in oats, rice, rye, sorghum and triticale. It has adverse effects on humans, animals, and crops that result in illnesses and economic losses. The aim of the present study was to investigate the effect of DON on some haematological (red blood cells - RBC, white blood cells - WBC, platelets - PLT, haemoglobin - HGB, packed cell volume - PCV and lymphocyte - LYM, biochemical (cholesterol, triglycerides, total protein, urea, calcium and phosphorus and anti- and pro-oxidants parameters (superoxide dismutase - SOD, glutathione peroxidase - GPx and ROS – reactive oxygen species in porcine blood in vitro. Significantly decreased content of total protein in the group with dose of 1000 ng.l-1 DON was observed compared with the control group. In other groups (E1 with 10 ng.l-1 DON and E2 with 100 ng.l-1 slightly lower values were measures in comparison with the control group. PLT significantly decreased in the experimental group E3 when compared with E1, E2, and the control group. Concentration of GPx in porcine blood significantly (P < 0.05 decreased in E1 against the control group. Concentration of SOD significantly (P < 0.05 decreased in group E2 in comparison with E1 group. The highest value of ROS was in E2 group. Other parameters were not influenced by The most important and the most common Fusarium mycotoxin is deoxynivalenol (DON. It occurs predominantly in grains such as wheat, barley, and maize and less often in oats, rice, rye, sorghum and triticale. It has adverse effects on humans, animals, and crops that result in illnesses and economic losses. The aim of the present study was to investigate the effect of DON on some haematological (red blood cells - RBC, white blood cells - WBC, platelets - PLT, haemoglobin - HGB, packed cell volume - PCV and lymphocyte - LYM, biochemical

  2. Effect of azadirachtin on haematological and biochemical parameters of Argulus-infested goldfish Carassius auratus (Linn. 1758).

    Science.gov (United States)

    Kumar, Saurav; Raman, R P; Kumar, Kundan; Pandey, P K; Kumar, Neeraj; Mallesh, B; Mohanty, Snatashree; Kumar, Abhay

    2013-08-01

    Argulosis hampers aquaculture production and alters the host physiology and growth. Azadirachtin is recognized as a potential antiparasitic agent against Argulus sp. The present study aimed to investigate the effect of different concentration of azadirachtin solution on haematological and serum biochemical parameters of Argulus-infested goldfish Carassius auratus. Ninety Argulus-infested goldfish were randomly divided into six equal groups. Fish of group 1-5 were treated with azadirachtin solution through bath of 1, 5, 10, 15 and 20 mg L(-1) as T1, T2, T3, T4 and T5, respectively, and group 6 was exposed to 2% DMSO solution without azadirachtin and considered as negative control T0(-). Along with six treatment groups, a positive control T0(+) of healthy goldfish free from Argulus infestation was also maintained. Parasitic mortality was evaluated after 3 days of consecutive bath treatment. After 7 days of post-treatment, the blood and serum were drawn from each of the treatment groups and haematological and serum biochemical parameters were evaluated. Total leucocyte count (TLC), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), blood glucose, total protein (TP), globulin, serum glutamate oxaloacetate transaminase (SGOT) and serum glutamate pyruvate transaminase (SGPT) were significantly (p azadirachtin have notable effects on activity of vital tissues function and physiology of the host. Argulus spp. from infested goldfish could be eliminated using bath treatment with solution of azadirachtin having concentration of 15 mg L(-1) and that also shifted haematological and serum biochemical parameters towards homeostasis.

  3. Transfusion treatment impact in the improvement of haematological parameters in patients with gastrointestinal bleeding

    Directory of Open Access Journals (Sweden)

    Iliriane Bunjaku

    2012-04-01

    Full Text Available Introduction: Transfusion treatment (TT is necessary in patients with gastrointestinal bleeding (GIB for lost blood substitution. This study was aimed at assessing the changes in haematological parameters  (hemoglobin, hematocrit, red blood cell count, white cell count, platelet count and prothrombin time before and after TT in anaemic patients with GIB in order to analyse the effect of this treatment.Methods: There have been included 293 patients with GIB (the average age was 57.3, ranged from 18-89 years who were treated with TT at the Internal Clinic at the University Clinical Center Prishtina during oneyear period. Data for applied blood product and results of the coagulation screen (PT were collected from the Kosovo’s Blood Transfusion Center (KBTC.Results: TT has been carried out in 404 episodes, with 714 units of concentrated red blood cells (78.6%, 189 units of fresh frozen plasma (20.8% and concentrated platelets (0.6%, with an average dose 3.1 fortransfunded patients. Average values of Hb before and after TT were 71.8 g/L and 81.4 g/L, respectively; while the average values of hematocrite before and after TT were 22.9% and 25.6%, respectively. The averageerythrocytes count before TT was 2.6 respectively after treatment 2.8(pConclusions: Having in mind difficult clinical and unsustainable situation in patients with gastrointestinal bleeding, the Transfusion Treatment resulted in the considerable improvement of the specific blood indicators.

  4. Transfusion treatment impact in the improvement of haematological parameters in patients with gastrointestinal bleeding

    Directory of Open Access Journals (Sweden)

    Iliriane Bunjaku

    2012-04-01

    Full Text Available Introduction: Transfusion treatment (TT is necessary in patients with gastrointestinal bleeding (GIB for lost blood substitution. This study was aimed at assessing the changes in haematological parameters  (hemoglobin, hematocrit, red blood cell count, white cell count, platelet count and prothrombin time before and after TT in anaemic patients with GIB in order to analyse the effect of this treatment.Methods: There have been included 293 patients with GIB (the average age was 57.3, ranged from 18-89 years who were treated with TT at the Internal Clinic at the University Clinical Center Prishtina during oneyear period. Data for applied blood product and results of the coagulation screen (PT were collected from the Kosovo’s Blood Transfusion Center (KBTC.Results: TT has been carried out in 404 episodes, with 714 units of concentrated red blood cells (78.6%, 189 units of fresh frozen plasma (20.8% and concentrated platelets (0.6%, with an average dose 3.1 fortransfunded patients. Average values of Hb before and after TT were 71.8 g/L and 81.4 g/L, respectively; while the average values of hematocrite before and after TT were 22.9% and 25.6%, respectively. The averageerythrocytes count before TT was 2.6 respectively after treatment 2.8(p<0.0001. The PT was carried out in the 43% of patients with GIB before treatment with FFP, but after that only in 2% of cases.Conclusions: Having in mind difficult clinical and unsustainable situation in patients with gastrointestinal bleeding, the Transfusion Treatment resulted in the considerable improvement of the specific blood indicators.

  5. Health assessment of free-ranging endangered Australian sea lion (Neophoca cinerea) pups: effect of haematophagous parasites on haematological parameters.

    Science.gov (United States)

    Marcus, Alan D; Higgins, Damien P; Gray, Rachael

    2015-06-01

    Evaluation of the health status of free-ranging populations is important for understanding the impact of disease on individuals and on population demography and viability. In this study, haematological reference intervals were developed for free-ranging endangered Australian sea lion (Neophoca cinerea) pups within the context of endemic hookworm (Uncinaria sanguinis) infection and the effects of pathogen, host, and environment factors on the variability of haematological parameters were investigated. Uncinaria sanguinis was identified as an important agent of disease, with infection causing regenerative anaemia, hypoproteinaemia, and a predominantly lymphocytic-eosinophilic systemic inflammatory response. Conversely, the effects of sucking lice (Antarctophthirus microchir) were less apparent and infestation in pups appears unlikely to cause clinical impact. Overall, the effects of U. sanguinis, A. microchir, host factors (standard length, body condition, pup sex, moult status, and presence of lesions), and environment factors (capture-type and year of sampling) accounted for 26-65% of the total variance observed in haematological parameters. Importantly, this study demonstrated that anaemia in neonatal Australian sea lion pups is not solely a benign physiological response to host-environment changes, but largely reflects a significant pathological process. This impact of hookworm infection on pup health has potential implications for the development of foraging and diving behaviour, which would subsequently influence the independent survival of juveniles following weaning. The haematological reference intervals developed in this study can facilitate long-term health surveillance, which is critical for the early recognition of changes in disease impact and to inform conservation management. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. Effects of a static magnetic field of 3.5 T on reproductive behaviour of mice, embryonic and foetal development and some haematological parameters

    International Nuclear Information System (INIS)

    Zimmermann, B.; Hentschel, D.

    1987-01-01

    To investigate possibilities of magnetic resonance imaging at high magnetic fields in humans, a whole-body magnet with a magnetic field density of 4 T was developed. Due to the few data that are available at present on biological effects and side effects of such high fields, a reproduction experiment with NMRI mice was performed using a crossover design. The mice were allowed to mate during a 7-day period within the field or after their stay in the field. The number of pregnant mice and foetuses were recorded and compared to the controls. Another group was held within the magnetic field during the whole period of pregnancy until day 18, one day before delivery. In all groups, development of the foetuses was studied. Additionally, haematological parameters of the males and females were estimated and necroscopy was performed. Brains, lungs and optical nerves were investigated using pathohistological techniques. It could be shown that in case of mating within the magnetic field, the number of pregnant mice was considerably reduced. This effect was, however, completely reversible if mating occurred after the stay in the field. Malformations retardations or an increased number of resorptions were never found. The haematological parameters were, in general, not changed. Necroscopy as well as pathohistological investigations showed no pathological alterations. Therefore, it appears that whereas high magnetic fields reduce the activity of mating behaviour, they do not exert any influence on physiological parameters. (orig.) [de

  7. Comparative evaluation of haematological parameters and erythrocyte membrane stability in pregnant and lactating goats in different seasons of tropical Savannah.

    Science.gov (United States)

    Habibu, B; Makun, H J; Yaqub, L S; Buhari, H U; Aluwong, T; Kawu, M U

    2017-09-01

    Haematological parameters and erythrocyte osmotic fragility (EOF) are commonly used as indicators of health status and erythrocyte membrane integrity. Variations in haematological parameters and EOF in late gestation and early lactation during the cold-dry (CDS), hot-dry (HDS) and rainy (RAS) seasons were studied in sixty (n = 60) Red Sokoto goats (20 goats for each season). The ambient temperatures and temperature-humidity index recorded were higher in the afternoon hours of the HDS and RAS, but lower in the morning hours of the CDS as compared with the thermoneutral zone of goats. Results revealed that the pregnant goats had significantly (P goats, higher (P goats. The EOF was significantly higher during lactation than pregnancy in the CDS and HDS. Similarly, the magnitude of the left shift in fragiligram during the CDS was more marked in pregnant compared with lactating goats. During gestation, the CDS had lower (P goats during the CDS. In conclusion, seasonal variations exist in physiology of erythrocytes of goats during the peri-partum period, with an increase in PCV and RBC, but a decrease in haemoglobin parameters in pregnant compared with lactating goats during the RAS. Erythrocyte stability and membrane integrity were higher in pregnant than lactating goats, and also higher during the CDS than the HDS and RAS, irrespective of reproductive status. This information may be useful in the design of animal breeding and is of value in animal welfare, research, diagnosis and management of haematological conditions during the peri-partum period. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. THE EFFECT OF SINGLE NICKEL AND COMBINED NICKEL AND ZINC PERORAL ADMINISTRATION ON HAEMATOLOGICAL PARAMETERS IN RABBITS

    Directory of Open Access Journals (Sweden)

    Jana Emrichová

    2013-06-01

    Full Text Available The aim of this study was to determine the effect of single nickel (NiCl2 and nickel in combination with zinc (ZnCl2 on selected haematological parameters of rabbits: white blood cell, red blood cell, haemoglobin, haematocrit, mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, platelets, mean platelet volume, red cell distribution width, lymphocytes, monocytes, eosinophils, neutrophils, basophils. Twenty rabbits of broiler line Californian were used in this experiment. The animals were divided into the five groups, four animals in each ones (control group K and experimental groups E1, E2, E3 and E4. Animals were fed ad libitum using KKV1 feeding mixture (FM with or without nickel and zinc addition for 90 days follows: group E1 received 17.5 g of NiCl2.100 kg-1 FM; group E2 35 g NiCl2.100 kg-1 FM; group E3 17.5 g NiCl2 + 30 g ZnCl2.100 kg-1 FM and group E4 35 g NiCl2 + 30 g ZnCl2.100 kg-1 FM. The parameters were analysed using Advia – 120. Blood was collected into tubes containing anticoagulant agents K – EDTA. Statistical analyse showed a significant changes (P 0.05. Nickel has negative effect on some haematological parameters, but zinc can eliminates its influence.

  9. Comparative haematological parameters of HbAA and HbAS genotype children infected with Plasmodium falciparum malaria in Yemen.

    Science.gov (United States)

    Albiti, Anisa H; Nsiah, Kwabena

    2014-04-01

    Sickle haemoglobin (HbS) is known to offer considerable protection against falciparum malaria. However, the mechanism of protection is not yet completely understood. In this study, we investigate how the presence of the sickle cell trait affects the haematological profile of AS persons with malaria, in comparison with similarly infected persons with HbAA. This study is based on the hypothesis that the sickle cell trait plays a protective role against malaria. Children from an endemic malaria transmission area in Yemen were enrolled in this study. Hematological parameters were estimated using manual methods, the percentage of parasite density on stained thin smear was calculated, haemoglobin genotypes were determined on paper electrophoresis, ferritin was measured using enzyme-linked immunosorbent assay, serum iron and TIBC were assayed using spectrophotometer, transferrin saturation index was calculated by dividing serum iron by TIBC and expressing the result as a percentage. Haematological parameters were compared in HbAA- and HbAS-infected children. Falciparum malaria parasitaemia was confirmed in the blood smears of 62 children, 44 (55.7%) of AA and 18 (37.5%) AS, so there was higher prevalence in HbAA children (P = 0.047). Parasite density was lower in HbAS- than HbAA-infected children (P = 0.003). Anaemia was prominent in malaria-infected children, with high proportions of moderate and severe forms in HbAA (P = 0.001). The mean levels of haemoglobin, packed cell volume, reticulocyte count, platelets count, lymphocytes, eosinophils, and serum iron were significantly lower while total leukocytes, immature granulocytes, monocytes, erythrocyte sedimentation rate, transferrin saturation, and serum ferritin were significantly higher in HbAA-infected children than HbAS-infected children. Infection with Plasmodium falciparum malaria caused more significant haematological alterations of HbAA children than HbAS. This study supports the observation that sickle cell trait

  10. Evaluation of haematology analyzer CELL-DYN 3700 SL

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    Enver Suljević

    2003-05-01

    Full Text Available Research on the parameters of full blood count and differential white blood count is included in the program of all medical laboratories of primary, secondary and tertiary health care levels. Today, all haematological tests are exclusively performed on the haematology analyzers. Automation of haematology laboratories is a result of the huge requires for haematological test performing, timely issuing of the haematological findings, and possibility of the usage of modern techniques.This work is an evaluation of laser haematology analyzer Cell-Dyn 3700 SL. It investigates the reliability of test results throughout the following parameters: precision, accuracy, sensitivity and specificity of determination methods. It also explores the influence of sample transferring and correlation with haematology analyzer MAXM Retti. Haematology parameters that have been investigated are: white blood cell (WBC, neutrophils (NEU, lymphocytes (LXM, monocytes (MONO, eosinophils (EOS, basophils (BASO, red blood cells (RBC, haemoglobin (HGB, haematocrit (HCT, mean corpuscular volume (MCV, mean corpuscular haemoglobin (MCHC red cell distribution width (RDW, platelet (PLT, mean platelet volume (MPV, plateletocrit (PCT, and platelet distribution width (PDW.The results confirms that precision of analyzer fulfils the reproducibility of testing parameters: WBC, RBC, HGB, MCV, MCH, MCHC, and PLT. Correlation coefficient values (r gained throughout the statistical analysis, that is linear regression results obtained throughout the comparison of two analyzers are adequate except for MCHC (r = 0.64, what is in accordance with literature data.Accuracy is tested by haematology analyzer method and microscopic differentiating method. Correlation coefficient results for granulocytes, lymphocytes and monocytes point the accuracy of methods. Sensitivity and specificity parameters fulfil the analytical criteria.It is confirmed that haematology analyzer Cell-Dyn 3700 SL is reliable for

  11. Effects of age and season on haematological parameters of donkeys during the rainy and cold-dry seasons

    Science.gov (United States)

    Zakari, Friday Ocheja; Ayo, Joseph Olusegun; Rekwot, Peter Ibrahim; Kawu, Mohammed Umar

    2015-12-01

    The aim of the study was to investigate the effects of age and season on haematological parameters of donkeys at rest during the rainy and cold-dry seasons. Thirty healthy donkeys divided into three groups based on their age served as the subjects. During each season, blood sample was collected from each donkey thrice, 2 weeks apart, for haematological analysis, and the dry-bulb temperature (DBT), relative humidity (RH) and temperature-humidity index (THI) were obtained thrice each day during the experimental period using standard procedures. During the rainy season, the mean DBT (33.05 ± 0.49 °C), RH (73.63 ± 1.09 %) and THI (84.39 ± 0.71) were higher ( P donkeys were higher ( P donkeys were higher ( P < 0.05) in the rainy than in the cold-dry season. In conclusion, PCV, RBC, Hb and LYM were considerably higher in foals than yearlings or adults during the rainy season, while erythrocytic indices and platelet counts were higher in adults or yearlings than in foals in both seasons. Erythrocytic indices, PLT and N/L were higher in the rainy than the cold-dry season in adults, yearlings and foals.

  12. Correlation Between Haematological Parameters, Kidney Function Tests and Liver Function Tests in Plasmodium Falciparum and Vivax Malaria

    Directory of Open Access Journals (Sweden)

    Mitul Chhatriwala

    2017-12-01

    Full Text Available Abstract: Malaria remains a major cause of morbidity and mortality in India. Plasmodium falciparum remains the main culprit although cases with vivax malaria are on the rise. Severe malaria as defined by the WHO criteria has high rate of complications and mortality. In our study we recruited microscopy positive falciparum and vivax malaria patients. Haematological and biochemical laboratory investigations were carried out in recruited patients. Both parameters were found to be significantly derailed in falciparum cases as compared to vivax. A direct correlation has been observed between kidney function tests (serum creatinine,serum urea and direct bilirubin levels across all cases of malaria. Hence these parameters can be used to identify and monitor the progress of cases of severe malaria as significant proportion of patients fulfilled the criteria of severe malaria in the cohort.

  13. The effect of depurinized milk draught diet on rat serum uric acid, lipid status and haematological parameters.

    Science.gov (United States)

    Kocic, G; Pavlovic, R; Nikolic, G; Stojanovic, D; Jevtovic, T; Sokolovic, D; Cencic, A; Stojanovic, S; Jelic, M; Zivanovic, S

    2012-08-01

    Hyperuricaemia and gout are closely related, but hyperuricaemia is an independent risk factor for endothelial damage, autoinflammation and haemodynamic abnormalities. Milk, generally known as a 'purine-free diet', is an essential protein source for patients suffering from hyperuricaemia and gout. As milk still contains different purine ribonucleotides, the new product, depurinized milk, almost free of purine nucleotides and uric acid, was produced. The potential effect of depurinized milk diet on serum uric acid (SUA) level, lipid parameters and blood haematological parameters was explored in rats after 72 h and 15 days, in relation to standard laboratory chow or the untreated milk diet. The beneficial effect on SUA was achieved when depurinized milk draught was given instead of standard chow for 72 h [28.39 ± 4.76 μm; p draughts enhanced haemoglobin concentration (p draught may meet the demand of healthy dairy product for population under hyperuricaemic risk. © 2011 Blackwell Verlag GmbH.

  14. Analysis of some biochemical and haematological parameters for Mucuna pruriens (DC) seed powder in male rats.

    Science.gov (United States)

    Chukwudi, Ndukwe Henry; Simeon, Omale; Chinyere, Aguiyi John

    2011-10-01

    The biochemical and haematological effects of the seed powder of Mucuna pruriens in male rats were evaluated to establish some biological properties of this potential biopesticide currently undergoing investigation. The result showed that Mucuna pruriens seed extract produced a significant (p<0.05) increase in white blood cell (WBC) count, as well as in bilirubin concentrations, alkaline phosphatase (ALP), protein and creatinine levels measured. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were significantly reduced (P<0.05) in comparison with the experimental control. PCV, Hb, albumin level and WBC differential counts gave no significant difference between treated and control groups. The results revealed metabolic imbalance in the rats which suggests a mild cholestasis effect of the extract.

  15. Correlation of routine haematological parameters between normal maternal blood and the cord blood of healthy newborns in selected hospitals of karachi

    International Nuclear Information System (INIS)

    Qaiser, D.H.; Ghori, G.M.; Sandila, M.P.; Omair, A.

    2013-01-01

    Objective: To determine any significant correlation between the routine haematological parameters of maternal blood and umbilical cord blood of their respective newborns. Study Design: Cross sectional study. Place and Duration of Study: The study was conducted at four public and private hospitals of Karachi including Sindh Government Qatar Hospital, Sindh Government Hospital, Liaquatabad, Ziauddin University Hospital and Chinniot Maternity and Child Hospital, respectively from July 2006 to April 2008. Methodology: Three milliliters venous blood was collected in EDTA containing tube for complete blood count of mothers before delivery. Five milliliters cord blood was collected from the umbilical cord of the babies immediately after delivery by clamping and cutting the babies' end of the cord. For haematological parameters a standard coultergram was done including haemoglobin, RBCs count, haematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), white blood cell count, differential leukocyte count and platelet count. Pearson's correlation co-efficient was used to determine an association between the maternal and cord blood parameters. Results: A total of 404 maternal and umbilical cord blood samples were analyzed. All the blood parameters including haemoglobin, RBCs count, HCT, MCV, MCH, white blood cell count, differential leukocyte count and platelet count were found to be high in cord blood as compared to the maternal blood, but they showed a very weak to negligible correlation. Mean Corpuscular Haemoglobin Concentration (MCHC), showed a moderate correlation. Conclusion: Routine haematological parameters of newborns are independent of maternal routine haematological parameters. (author)

  16. Nuclear haematology

    International Nuclear Information System (INIS)

    Masjhur, J.S.

    1992-01-01

    Nuclear techniques have been applied to study diagnose and treat various haematological disorders for more than five decades. Two scientists are regarded as pioneers in this field, i.e. John Lawrence who in 1938 used 32 P to treat chronic myeloid leukaemia and George Hevessy who used 32 P labelled erythrocytes to measure blood volume in 1939. At present, many nuclear medicine procedures are available for diagnosis and therapy of a variety of haematological disorders. Although nuclear techniques are somewhat complex, they give direct and quantitative assessment of the kinetics of blood elements as compared to other non-isotopic haematological tests. Basically, equipment required for nuclear haematology is very simple such as well scintillation counters to measure radioactivity in blood samples. More sophisticated equipment like rectilinear scanner or gamma camera is required when imaging is necessary. An overview of the basic principles and clinical applications of nuclear haematology is given

  17. Nuclear haematology

    Energy Technology Data Exchange (ETDEWEB)

    Masjhur, J S

    1993-12-31

    Nuclear techniques have been applied to study diagnose and treat various haematological disorders for more than five decades. Two scientists are regarded as pioneers in this field, i.e. John Lawrence who in 1938 used {sup 32}P to treat chronic myeloid leukaemia and George Hevessy who used {sup 32}P labelled erythrocytes to measure blood volume in 1939. At present, many nuclear medicine procedures are available for diagnosis and therapy of a variety of haematological disorders. Although nuclear techniques are somewhat complex, they give direct and quantitative assessment of the kinetics of blood elements as compared to other non-isotopic haematological tests. Basically, equipment required for nuclear haematology is very simple such as well scintillation counters to measure radioactivity in blood samples. More sophisticated equipment like rectilinear scanner or gamma camera is required when imaging is necessary. An overview of the basic principles and clinical applications of nuclear haematology is given

  18. The effects of strawberry tree water leaf extract, arbutin and hydroquinone on haematological parameters and levels of primary DNA damage in white blood cells of rats.

    Science.gov (United States)

    Jurica, Karlo; Brčić Karačonji, Irena; Kopjar, Nevenka; Shek-Vugrovečki, Ana; Cikač, Tihana; Benković, Vesna

    2018-04-06

    Strawberry tree (Arbutus unedo L., Ericaceae) leaves represent a potent source of biologically active compounds and have been used for a long to relieve symptoms of various health impairments and diseases. Two major compounds related to their beneficial activities in animals and humans are arbutin and hydroquinone. To establish potential benefit/risk ratio associated with daily oral administration of strawberry tree water leaf extract, arbutin and hydroquinone in doses expected to be non-toxic. We performed a 14-day and a 28-day study on male and female Lewis rats and evaluated main haematological parameters and the effects of treatments on the levels of primary DNA damage in white blood cells (WBC) using the alkaline comet assay. Our findings suggest no significant changes in the haematological parameters following prolonged exposure to strawberry tree water leaf extract, arbutin, and hydroquinone. However, hydroquinone causes increased, and extract as well as arbutin decreased WBC count in male rats compared to control after 14 days of treatment. DNA damage measured in WBC of rats treated with all compounds was below 10% of the DNA in the comet tail, which indicates low genotoxicity. The genotoxic potential of strawberry water leaf extract was within acceptable limits and reflected effects of a complex chemical composition upon DNA. We also observed slight gender- and exposure time- related differences in primary DNA damage in the leucocytes of control and treated rats. Future studies should investigate which doses of strawberry tree water leaf extract would be most promising for the potential use as a substitute for bearberry leaves for treatment of urinary infection. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Growth performance and haematology of the laboratory rat, rattus norvegicus fed on protein supplements and heavy metals

    International Nuclear Information System (INIS)

    Omotoso, O.T.; Sanya, B.T.

    2007-01-01

    Laboratory rat Rattus norvegicus. fed on poultry growers mash plus additional protein supplements and some heavy metals, was studied for the growth and the haematological parameters. All the dietary supplements resulted in an increase in the growth of the rats. The rats, fed on growers mash and prawn meal showed the best growth within 7 weeks. Effects of diets were significantly, correlated at 0.01 level. Weight loss was recorded in case of all heavy Metal-laced diets, however, calcium sulphate-laced diets resulted in an increase in growth. Mercurous chloride was the most toxic salt which resulted in the greatest weight loss. Haematological analysis of rats revealed that RBC/sub s/ were higher in the case of heavy metal-laced diets than heavy metal-free diets. Generally, RBC counts were higher in females than in males within a group. Fish meal and prawn meal feeding. (author)

  20. EFFECTS OF HIGHER LEVELS OF CHROMIUM AND COPPER ON SOME HAEMATOLOGICAL PARAMETERS AND SERUM PROTEINS IN BROILERS

    Directory of Open Access Journals (Sweden)

    M. Tariq Javed, F, Ahmad. N, Z, Rafique1 and M, Bashir

    2003-01-01

    Full Text Available Effects of higher levels of chromium alone and in combination with copper were investigated in broiler chicks divided into seven equal groups viz. A, B, C, D, E, F and G. Group G served as control receiving no treatment. Groups A, B and F received chromium chloride at the rate of 2 g/kg and nicotinic acid 150 mg/kg feed while C, D and F received chromium chloride 8 g/kg and nicotinic acid 150mg/kg. Broilers of groups A and C received copper sulfate at the rate of 200 mg/kg while groups Band D 400 mg/kg feed. Haematological parameters studied revealed non-significant difference between treatment groups and control in haemoglobin concentration and total erythrocyte counts. However, only at 4th week, lower PCV was observed in birds fed higher levels of chromium chloride alone. Increase in TLC was observed in birds fed low chromium alone or' with low levels of copper. Results of serum proteins including total protein, albumin and globulin during first three weeks showed significantly or relatively lower values in treatment groups than control. Serum globulins generally revealed non-significant difference between treatment groups and control.

  1. Comparative study of growth traits and haematological parameters of Anak and Nigerian heavy ecotype chickens fed with graded levels of mango seed kernel (Mangifera indica) meal.

    Science.gov (United States)

    Mbunwen, Ndofor-Foleng Harriet; Ngongeh, Lucas Atehmengo; Okolie, Peter Nzeribe; Okoli, Emeka Linus

    2015-08-01

    One hundred fifty Anak and 120 Nigerian heavy local ecotype (NHLE) chickens were used to study the effects of feeding graded levels of mango seed kernel meal (MKM) replacing maize diet on growth traits and haematological parameters. A 2 × 5 factorial arrangement was employed: two breeds and five diets. The birds were randomly allocated to five finisher diets formulated such that MKM replaced maize at 0, 10, 20, 30 and 40% (T1, T2, T3, T4 and T5) inclusion levels, respectively. The effect of breed and dietary treatments on growth performance and blood characteristics were determined. The results showed a significant (P  0.05) when the breeds and treatments were compared. It was concluded that inclusion of dietary MKM below 30% could replace maize in the diets of Anak and NHLE growing chickens without adverse effect on growth performance and blood constituents. This work suggests that genetic differences exist in growth traits of these breeds of chickens. This advantage could be useful in breed improvement programmes and better feeding managements of the NHLE and Anak chickens.

  2. Growth performance, blood parameters and carcass characteristics ...

    African Journals Online (AJOL)

    This study was carried out with one hundred and twenty (120) day-old marshal chicks to investigate the effect of Maxigrain® enzyme supplementation of corn bran based diets on growth performance, carcass characteristics, haematology and serum biochemistry of broilers in an eight weeks experiment. Four experimental ...

  3. Effect of prebiotic, probiotic and G-probiotic SPL® on certain haematological parameters in broiler chickens

    Directory of Open Access Journals (Sweden)

    Hanamanta Nyamagonda

    Full Text Available A total of one hundred unsexed, day old and straight run commercial Cobb - 400 broiler chicks were randomly divided in to five groups consisting of twenty chicks in each group. The control group received only the basal diet (Group I and the treatment groups were administered with prebiotic (Lactose @ 2.5%, probiotic (Lactobacillus acidophilus @ 0.1% and their combination (Lactose @ 2.5% plus Lactobacillus acidophilus @ 0.1% in drinking water, respectively for Group II, Group III and Group IV  and commercial product G-Probiotic Spl® (containing five species of probiotic organisms, three digestive enzymes and liver extract, @ 0.05 % in the feed to Group V from day one to 42 to evaluate the hematological parameters in broiler chickens such as total erythrocyte count, hemoglobin content, packed cell volume and total leukocyte count on day 21 and 42 of the experiment. There were non significant (P>0.05 differences between different groups on both the days of observation with respect to total erythrocyte count, hemoglobin content and packed cell volume. But, the total leukocyte count in treatment groups significantly (P<0.05 differed from control group on day 21 and 42 which may be possibly due to improved immunostimulatory effect and physiological well-being of the birds received  prebiotic and probiotic. [Vet World 2009; 2(9.000: 344-346

  4. The effect of fasting during Ramadan on parameters of the haematological and steroidal modules of the athletes biological passport - a pilot study.

    Science.gov (United States)

    Alsaadi, K; Voss, S C; Kraiem, S; Alwahaibi, A; Alyazedi, S; Dbes, N; Goebel, R; Mohamed-Ali, V; Alsowaidi, S; Seyam, A M; Bashraheel, A S; Alsayrafi, M; Georgakopoulos, C

    2015-01-01

    This study investigated the effect of Ramadan on the haematological and steroid module of the Athletes Biological Passport (ABP) of the World Anti-Doping Agency (WADA). Nine healthy physically active subjects were tested in the morning and afternoon for two days before and three days during Ramadan. Sample collection and all analyses were performed according to WADA technical documents. Although there were significant changes in the haemoglobin concentration during Ramadan, especially during the first fasting week, none of the subjects in this study exceeded the individually calculated thresholds of the ABP. No significant effects on testosterone/epitestosterone (T/E) ratio were observed but only the afternoon specific gravity (SG) of the urine was elevated. Thus, when urinary steroid concentrations are required, SG corrections need to be performed. The haematological and the steroid module of the ABP can be reliably applied during Ramadan as the observed changes are only marginal. Copyright © 2015 John Wiley & Sons, Ltd.

  5. Effects of different doses of doxycycline hyclate on haematological parameters of dogs with ehrlichiosis

    Directory of Open Access Journals (Sweden)

    Mariana Cristina Hoeppner Rondelli

    2016-11-01

    Full Text Available This study aimed to compare the effects of two doses of doxycycline hyclate on red blood cells, hemoglobin, hematocrit, white blood cells and platelets of dogs with ehrlichiosis. Group I, comprised of healthy dogs (n=6, negative on serology for Ehrlichia canis and Leptospira spp., real time PCR for E. canis and Anaplasma platys, and on semi–nested PCR for Babesia canis; Groups II (n=6 and III (n=6, comprised of dogs with suggestive clinical history, positive serology and/or real time PCR for E. canis, negative on research for anti-Leptospira spp. antibodies and real time PCR for A. platys, and on semi–nested PCR for B. canis were studied. Sick dogs were treated with doxycycline hyclate every 12 hours, by mouth, for 30 days (5 mg/kg, group II; 10 mg/kg, group III. Complete blood counts were performed before, after 15 days, and 10 days after period of treatment was complete. No difference between groups at the studied time points were noticed for red blood cells, hemoglobin, haematocrit and white blood cells. Difference was observed for platelets between group I and groups II and III (p<0.0001 at the study onset. After 15 days of treatment, the mean platelet for group III was lower than groups I (p=0.008 and II (p=0.0007, indicative of persistent thrombocytopenia, already absent in group II. No difference between groups was noticed at final time point, which suggests that both treatments increased platelets in dogs naturally infected with E. canis.

  6. Toxicity of Neem Leaf Extracts (Azadirachta indica A. Juss on Some Haematological, Ionoregulatory, Biochemical and Enzymological Parameters of Indian Major Carp, Cirrhinus mrigala

    Directory of Open Access Journals (Sweden)

    M. Saravanan

    2011-10-01

    Full Text Available In the present study, the median lethal concentration (LC 50 of neem leaf extract to Cirrhinus mrigala for 24 h was found to be 1.035 g l-l. During the study period, the haematological parameters including Hb, Hct, RBC, MCV, MCH and MCHC levels were significantly decreased in neem leaf extract exposed fish when compared to the control fish whereas WBC count was increased. Similarly, plasma Na+ and Cl- levels were significantly lower and K+ level were significantly higher when compared to the control. In biochemical study, elevated plasma glucose and induced protein levels were noticed. The enzymes, glutamate oxaloacetate transaminase (GOT and glutamate pyruvate transaminase (GPT activities were increased significantly in gill, liver and muscle of treated fish compared to that of their control groups. The results of the present investigation suggest that neem leaf extracts affects the hematological, ionoregulatory, biochemical and enzymological parameters of fish and alterations of these parameters can be useful in environmental biomonitoring of neem based products in freshwater environment.Keywords: Azadirachta indica, Acute toxicity, Cirrhinus mrigala, Haematology, Ion regulation, Biochemical and Enzymological parameters.

  7. Evaluation of the haematological parameters in Piaractus mesopotamicus Holmberg (Osteichthyes, Characidae with Argulus sp. (Crustacea, Branchiura infestation and treatment with organophosphate

    Directory of Open Access Journals (Sweden)

    Marcos Tavares-Dias

    1999-06-01

    Full Text Available Haematological parameters as erythrocytes, leukocytes and plasma glucose in Piaractus mesopotamicus Holmberg, 1887 were analyzed. Fish were parasitized with Argulus sp. (Crustacea, Branchiura and treated with 0.4 mg of thriclorphon 500/L water. The effects of parasitism and the action of the treatment were evaluated. Parasitized fish showed greater number of monocytes (P>0.05 and special granulocitic cells (P0.05. Organophosphate treatment presented significantly reduction (P>0.05 in red blood cells (RBC and hemoglobin.

  8. Goat Milk Kefir Supplemented with Porang Glucomannan Improves Lipid Profile and Haematological Parameter in Rat Fed High Fat and High Fructose Diet

    Directory of Open Access Journals (Sweden)

    Nurliyani

    2018-03-01

    Full Text Available Background and Aims: Diet with a high fat and high sugar is associated with an increased incindence of the metabolic syndrome. Kefir has been known as a natural probiotic, while glucomannan from porang (Amorphophallus oncophyllus tuber was demonstrated as prebiotic in vivo. Probiotics and prebiotics can be used adjuvant nutritional therapy for metabolic syndrome. The aim of this study was to evaluate the effect of goat milk kefir supplemented with porang glucomannan on the lipid profile and haematological parameters in rats fed with a high-fat/high-fructose (HFHF diet.

  9. Growth performance and haematological and immunological indices of rainbow trout (Oncorhynchus mykiss fingerlings supplemented with dietary Ferulago angulata (Schlecht Boiss

    Directory of Open Access Journals (Sweden)

    Somayeh Bohlouli

    2016-01-01

    Full Text Available In this study, the effects of Ferulago angulata extract on the growth, haematological, and immunological indices of rainbow trout (Oncorhynchus mykiss fingerlings were evaluated. Basal diet was supplemented with 0 (control, 0.5, 1, and 2 g·kg-1 F. angulata and was randomly allocated to experimental fish of an initial average weight of 7.45 ± 0.02 g. After 8 weeks of experiment, the fish supplemented with F. angulata extract showed increased but non-significant (P > 0.05 growth performance. No significant differences were found between trial control groups in haematological indices such as red blood cell count, haematocrit, and haemoglobin, but there was a significant increase in white blood cells, lymphocytes, neutrophils and monocytes in the F. angulata extract groups (P < 0.05. Also, there were significant differences between the fish supplemented with dietary F. angulata extract and the control group regarding immunological indices, including immunoglobulin M, lysozyme, and classical and alternative complement pathway (P < 0.05. These findings suggest that the administration of F. angulata extract has a positive effect on the immunological indices and the immune system activity in rainbow trout fingerling.

  10. Radioprotection of whole-body γ-irradiation-induced alteration in some haematological parameters by cysteine, vitamin E and their combination in rats

    International Nuclear Information System (INIS)

    Shaheen, A.A.; Hassan, S.M.

    1991-01-01

    Radioprotective effect of cysteine, vitamin E and their combination on γ-irradiation-induced alteration in some haematological parameters in male rats has been studied 24 and 48 hrs after whole-body γ-irradiation at a dose level of 7.5 Gy. The results of this study reveal that γ-irradiation caused a significant decrease in red blood cells (RBCs) count with insignificant change in hemoglobin level, 24 and 48 hrs postirradiation, γ-irradiated rats showed as well a progressive decrease in their blood ATP, and serum-SH levels with a significant increase in blood glutathione (GSH) level. Administration of cysteine or vitamin E preceeding γ-radiation exposure gave a significant radioprotection to the above haematological parameters. However, combination of both agents afforded a better protection, so that most of the measured parameters were restored to the pre-irradiated values. Finally, the data demonstrate that the radioprotection provided by combined adminsistration of vitamin E and cysteine is feasible and perhaps, even more efficient against radiation injury to RBCs. This will appreciate the usage of such combination in protecting the patient during radiotherapy. (orig.) [de

  11. Evaluation of bone marrow examinations performed by an advanced nurse practitioner: an extended role within a haematology service.

    LENUS (Irish Health Repository)

    Kelly, Mary

    2012-01-31

    PURPOSE: Traditionally, medical personnel have undertaken bone marrow (BM) examination. However, specially trained nurses in advanced practice roles are increasingly undertaking this role. This paper presents the findings from an audit of BM examinations undertaken by an advanced nurse practitioner (ANP) at a regional haematology specialist centre. METHODS: The audit evaluated the quality of BM examinations performed by the ANP over the past two years (September 2007-September 2009). Over the two year period, 324 BM examinations were performed at the centre of which 156 (48.1%) were performed by the ANP. A random sample of 30 BM examinations undertaken by the ANP were analysed by the consultant haematologist. RESULTS: All 30 BM examinations undertaken by the ANP were sufficient for diagnosis. CONCLUSIONS: The ANP is capable and competent to obtain BM samples which are of a sufficient quality to permit diagnosis.

  12. Baseline Haematology and Erythrocyte Morphological Changes of ...

    African Journals Online (AJOL)

    Summary: This study evaluates the haematological parameters and the observed erythrocytes morphological changes in dogs raised in Ibadan, Oyo State in the south western part of Nigeria. Blood samples were collected from sixty-four apparently healthy dogs. The haematological parameters of the blood samples ...

  13. Effects of Aqueous Root Bark Extracts of Anogeissusleiocarpus (DC Guill&Perrand TerminaliaavicennioidesGuill&Perr on Redox and Haematological Parameters of Diethylnitrosamine-Administered Rats

    Directory of Open Access Journals (Sweden)

    Amadu Kayode Salau

    2015-11-01

    Full Text Available Background: This study investigated the protective effects of aqueous extracts of Anogeissusleiocarpus (DC Guill&Perr (family: Combretaceae and Terminaliaavicennioides Guill&Perr (family: Combretaceae root barks, as well as their 1:1 (w/w mixture on liver redox and haematological parameters of diethylnitrosamine-treated rats. Methods: Rats were orally administered distilled water, diethylnitrosamine (30 mg/kg body weight once a week on weeks 3 and 4, curcumin (200 mg/kg body weight, extracts and 1:1 mixture (200, 400 and 800 mg/kg body weight for 4 weeks. Malondialdehyde, markers of oxidative stress and hematological indices were evaluated. Results: The extracts and their mixture significantly (P<0.05 reversed the diethylnitrosamine-induced alterations in the levels of liver malondialdehyde, superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, glucose 6-phosphate dehydrogenase, glutathione, vitamin C and platelet counts. The other haematological parameters (red blood cell count, haemoglobin concentration, packed cell volume, mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, white blood cell count, lymphocyte count and neutrophil count were not affected by diethylnitrosamine and extracts. Conclusion: The extracts possess antioxidant, hepatoprotective and haemoprotective activities that compared well with curcumin. These activities were better exhibited by the mixture than the individual extracts.

  14. Haematological characteristics of Brazilian Teleosts: III. Parameters of the hybrid tambacu (Piaractus mesopotamicus Holmberg x Colossoma macropomum Cuvier (Osteichthyes, Characidae

    Directory of Open Access Journals (Sweden)

    Marcos Tavares-Dias

    2000-12-01

    Full Text Available Fifty six specimens of the hybrid "tambacu" (Piaractus mesopotamicus Holmberg, 1887 male x Colossoma macropomum Cuvier, 1818 female were collected from fishfarm of Guariba, São Paulo, to evaluate their haematology. Fishes presented 400.0 to 3,100.0 g total weight and 20.0 to 52.0 cm total length. Haemoglobin, haematocrit, mean corpuscular haemoglobin content (MCHC and percentage of defense blood cells including leucocytes and thrombocytes, were studied. Statistical analysis showed positive correlation (P<0.01 between haematocrit, MCHC and haemoglobin rate. Nevertheless, thrombocytes and lymphocytes showed negative correlation (P<0.01.

  15. Vitamins and administration periods effects on haematological ...

    African Journals Online (AJOL)

    Vitamins and administration periods effects on haematological parameters of broiler ... Data obtained on haematological indices were subjected to Analysis of ... été répartis sur base de l'égalisation du poids en neuf (9) groupes de traitement, ...

  16. Evaluation of biochemical and haematological parameters and prevalence of selected pathogens in feral cats from urban and rural habitats in South Korea.

    Science.gov (United States)

    Hwang, Jusun; Gottdenker, Nicole; Min, Mi-Sook; Lee, Hang; Chun, Myung-Sun

    2016-06-01

    In this study, we evaluated the potential association between the habitat types of feral cats and the prevalence of selected infectious pathogens and health status based on a set of blood parameters. We live-trapped 72 feral cats from two different habitat types: an urban area (n = 48) and a rural agricultural area (n = 24). We compared blood values and the prevalence of feline immunodeficiency virus (FIV), feline leukaemia virus (FeLV) and haemotropic Mycoplasma infection in feral cats from the two contrasting habitats. Significant differences were observed in several blood values (haematocrit, red blood cells, blood urea nitrogen, creatinine) depending on the habitat type and/or sex of the cat. Two individuals from the urban area were seropositive for FIV (3.0%), and eight (12.1%) were positive for FeLV infection (five from an urban habitat and three from a rural habitat). Haemoplasma infection was more common. Based on molecular analysis, 38 cats (54.3%) were positive for haemoplasma, with a significantly higher infection rate in cats from rural habitats (70.8%) compared with urban cats (47.8%). Our study recorded haematological and serum biochemical values, and prevalence of selected pathogens in feral cat populations from two different habitat types. A subset of important laboratory parameters from rural cats showed values under or above the corresponding reference intervals for healthy domestic cats, suggesting potential differences in the health status of feral cats depending on the habitat type. Our findings provide information about the association between 1) blood values (haematological and serum biochemistry parameters) and 2) prevalence of selected pathogen infections and different habitat types; this may be important for veterinarians who work with feral and/or stray cats and for overall cat welfare management. © ISFM and AAFP 2015.

  17. Material parameters for thermoelectric performance

    Indian Academy of Sciences (India)

    The thermoelectric performance of a thermoelement is ideally defined in terms of the so-called ... However, there are other parameters which are fairly good indicators ... Whereas a final deciding factor reflecting on .... matter of a future work.

  18. Material parameters for thermoelectric performance

    Indian Academy of Sciences (India)

    The thermoelectric performance of a thermoelement is ideally defined in terms of the so-called figure-of-merit = 2 / , where , and refer respectively to the Seebeck coefficient, electrical conductivity and thermal conductivity of the thermoelement material. However, there are other parameters which are fairly good ...

  19. Haematological and immunological indicators for radiation exposure

    International Nuclear Information System (INIS)

    Dehos, A.

    1990-01-01

    It is examined if haematological and immunological parameters can be used as biological indicators for radiation exposure. Additional criteria for biological indicators, apart from the dose dependence of the effect, are listed here. The state of the art concerning the development of haematological and immunological indicators is discussed. Several haematological indicators are currently used in diagnosis when excess radiation exposure has occurred (e.g., after the Chernobyl accident). However, further research work has to be done in the field of immunological indicators. (orig.) [de

  20. Balanced performance measurement in research hospitals: the participative case study of a haematology department.

    Science.gov (United States)

    Catuogno, Simona; Arena, Claudia; Saggese, Sara; Sarto, Fabrizia

    2017-08-03

    The paper aims to review, design and implement a multidimensional performance measurement system for a public research hospital in order to address the complexity of its multifaceted stakeholder requirements and its double institutional aim of care and research. The methodology relies on a participative case study performed by external researchers in close collaboration with the staff of an Italian research hospital. The paper develops and applies a customized version of balanced scorecard based on a new set of performance measures. Our findings suggest that it can be considered an effective framework for measuring the research hospital performance, thanks to a combination of generalizable and context-specific factors. By showing how the balanced scorecard framework can be customized to research hospitals, the paper is especially of interest for complex healthcare organizations that are implementing management accounting practices. The paper contributes to the body of literature on the application of the balanced scorecard in healthcare through an examination of the challenges in designing and implementing this multidimensional performance tool. This is one of the first papers that show how the balanced scorecard model can be adapted to fit the specific requirements of public research hospitals.

  1. Performance, biochemical and haematological responses, and relative organ weights of laying hens fed diets supplemented with prebiotic, probiotic and synbiotic.

    Science.gov (United States)

    Tang, Shirley Gee Hoon; Sieo, Chin Chin; Ramasamy, Kalavathy; Saad, Wan Zuhainis; Wong, Hee Kum; Ho, Yin Wan

    2017-08-17

    The increasing trend of ban on the use of antibiotic growth promoters (AGPs) across the globe in the poultry industry has led to a growing need for alternatives to AGPs. Prebiotic, probiotic and their combination as a synbiotic have been considered as potential alternatives. This study aimed to investigate the effects of a prebiotic (isomaltooligosaccharide, IMO), a probiotic (PrimaLac®), and their combination (synbiotic) on hen performance, biochemical and haematological responses, and relative organ weights from 20 to 52 weeks of age. Supplementation of 1% IMO (PRE), 0.1% PrimaLac® (PRO) and 1% IMO + 0.1% PrimaLac® (SYN) improved (P feed intake and egg production at 20-36 weeks of age; body weight gain, feed conversion ratio and egg mass at 20-36 and 20-52 weeks of age; and egg weight at 20-36, 37-52 and 20-52 weeks of age. Compared to control-fed hens at 20-36 weeks of age, PRO- and SYN-fed hens produced less (P hens produced more large size eggs. From 37 to 52 weeks of age, PRE-, PRO- or SYN-fed hens produced less (P hens from 20 to 52 weeks of age. These results demonstrated the use of PRE, PRO and SYN as alternative feed additives to AGPs for improving the health and productivity of hens, while PRO is the best for commercial layer production to yield maximum profit.

  2. Effect Of Garlic Oil On Haematological Parameters, Blood Respiratory Functions And Serum Testosterone In Male Rats Exposed To An Electromagnetic Field

    International Nuclear Information System (INIS)

    EL-SHAFEY, A.A.; ALI, E.A.; MARZOOK, E.A.

    2009-01-01

    This study was conducted to investigate the biological effects of exposure to an electromagnetic field (EMF, 900 MHz) emitted from mobile base station antenna for 4 weeks on haematological parameters, respiratory function of blood (blood gases, acid-base status) and oxygen equilibrium curves beside the levels of serum testosterone and possible protective role of garlic oil (250 mg/kg b.w/day for 4 weeks) in male albino rats. The results revealed significant reductions in haemoglobin (Hb) contents, total leucocytes (WBC) count, mean corpuscular volume (MCV) and haematocrit value (Hct %) in rats exposed to EMF (GI). These reductions have been ameliorated by garlic oil treatment (GII). Significant increases in oxygen partial pressure (PO 2 ) were observed in arterial (a) and alveolar (A) blood. These increases were reduced by garlic oil treatment. The percent oxygen saturation (% O 2 sat) was significantly decreased in arterial while it was increased significantly in venous blood in both treated groups. There was a significant reduction in carbon dioxide partial pressure (PCO 2 ) in the arterial blood after exposure to EMF (GI) which was decreased by garlic oil treatment. Significant reductions were recorded in arterial blood pH, bicarbonate (HCO - 3 ), total carbon dioxide (TCO 2 ) and arterial and venous blood base excess (BE). These reductions were decreased by garlic oil treatment in GII. The blood oxygen equilibrium curves (OEC) of (GI) and (GII) were shifted to the right compared to that of control group with non-significant increases in P 50 . The level of serum testosterone was highly significantly decreased in GI. This reduction was decreased in garlic oil treated group (GII). It can be concluded that garlic oil has a protective role against the hazardous effects of EMF.

  3. Effect of subacute poisoning with bifenthrin on locomotor activity, memory retention, haematological, biochemical and histopathological parameters in mice.

    Science.gov (United States)

    Nieradko-Iwanicka, B; Borzecki, A; Jodlowska-Jedrych, B

    2015-02-01

    Bifenthrin (BIF) is a pyrethroid (PYR) insecticide. The target point for PYR's toxic action are voltage sensitive sodium channels in the central nervous system (CNS). Intoxication with PYRs results in motor activity impairment and death in insects. Although PYRs are considered to be safe for mammals, there were numerous cases of pyrethroid poisoning in humans, animals and pets described. The general population is chronically exposed to PYRs via grain products, dust and indoor air. Therefore new questions arise: whether PYRs act in a dose-additive fashion in the course of subacute poisoning, are there other target organs (but brain) for BIF and if there is one common mechanism of its' toxic action in different organs. The objective of this work was to characterize the effect of BIF at the doses of 4 or 8 mg/kg injected intraperitoneally (i.p.) daily for 28 consecutive days on memory and motor activity, hematological, biochemical and histopathological parameters in mice. BIF at the doses of 8 mg/kg or 4 mg/kg of body mass was administered i.p. daily to the mice for 28 consecutive days. Motor function was measured on day 1, 7, 14 and 28 and memory retention was tested in a passive avoidance task on day 2, 7, 14 and 28. BIF significantly impaired memory retention on day 2. BIF decreased locomotor activity at every stage of the experiment in a single dose depending manner. No behavioral cumulative effect was observed. Subacute poisoning with the higher dose of BIF caused anaemia, elevated white blood cell count (WBC), elevated alanine transaminase (ALT), superoxide dismuthase (SOD), and decreased glutathione peroxidase (GPx) activity. Lymphocyte infiltrates were visualized in the livers. subacute poisoning with BIF decreases locomotor activity in a single dose proportionate manner. BIF damages also the liver and alters blood morphology. The possible common mechanism of these effects can be oxidative stress.

  4. EFFECT OF SOAKED AND FERMENTED AFRICAN LOCUST BEAN (Parkia biglobosa SEED MEAL ON GROWTH PERFORMANCE, HAEMATOLOGICAL PROFILE AND NUTRIENT DIGESTIBILITY OF BROILER CHICKENS

    Directory of Open Access Journals (Sweden)

    M.S. Tamburawa

    2017-04-01

    Full Text Available African locust bean (Parkia biglobosa seed is rich in protein and has recently found its way into the feed industry. This research was conducted to determine the growth performance, haematological profile and nutrient digestibility by broiler chickens fed diets containing soaked and fermented African locust bean (Parkia biglobosa seed meal (SFALBSM. Five diets were formulated in which SFALSBM was included at graded levels of 0, 7.5, 15, 22.5 and 30% designated as T1, T2, T3, T4 and T5 respectively. Two hundred and twenty five (225 day old broiler chickens (Marshall Strain were fed these diets in a completely randomized design and each treatment was replicated three times with 15 birds per replicate. The experiment lasted 8 weeks (4week starter phase and 4week finisher phase. The results of performance of broiler chicks at starter phase showed there were differences (P0.05 on digestibility of dry matter, crude protein and ash. The crude fibre, ether extract and nitrogen free extract digestibility were affected by treatments (P<0.05. Birds fed T3 had highest crude fibre digestibility value (P<0.05. It was concluded that soaked and fermented African locust bean seed meal can be included in broiler chickens diets up to 15% dietary level at the starter phase and 22.5% at the finisher phase without any adverse effect on performance, haematological profile and nutrient digestibility.

  5. Growth performance, haematological traits, meat variables, and effects of treadmill and transport stress in veal calves supplied different amounts of iron.

    Science.gov (United States)

    Lindt, F; Blum, J W

    1994-06-01

    Effects of serum iron (Fe), haematological variables and on blood lactate levels before and after treadmill exercise or transport to the slaughterhouse, on meat traits, and on growth performance of feeding milk replacer (MR), planned to contain 10, 20, 30, 40, 50 or 80 mg Fe/kg, were studied in veal calves. If supplied less than 50 mg Fe/kg MR, calves developed hypoferraemia and anaemia, the degree of which was dependent on Fe intake. Serum Fe concentration, saturation of transferrin with Fe and the degree of anaemia in calves fed 20 or 10 mg Fe/kg MR were nearly identical. Serum Fe concentration and haematological traits barely changed in calves fed 50 mg Fe/kg MR during the growth trail, but serum Fe concentration increased when MR contained 80 mg Fe/kg in calves fed 50 or more Fe/kg MR. Growth performance was smaller in calves fed 10 mg Fe/kg MR than in those fed greater amounts of Fe/kg MR. Carcass taxation was inversely related to Fe intake. In conclusion, MR containing only 10 mg Fe/kg caused marked anaemia and reduced growth performance. Feeding MR with only 20 mg Fe/kg is not necessarily sufficient to prevent development of severe anaemia. Feeding MR with 50 mg Fe/kg would seem to be physiologically the most appropriate amount of Fe for veal calves, but was too high for acceptable carcass taxation.

  6. Seasonal and sex-specific variations in haematological parameters in 4 to 5.5-month-old infants in Guinea-Bissau, West Africa

    DEFF Research Database (Denmark)

    Bæk, Ole; Jensen, Kristoffer Jarlov; Andersen, Andreas

    2017-01-01

    were wider and generally higher than those from a US population of comparable age, but neutrophil levels were notably lower in Guinea-Bissau. Conclusions: The study indicated that eosinophil and platelet counts of infants were subject to seasonal variations. The reference ranges for haematological...... values were comparable to other African populations and corroborated that neutropenia regularly occurs in African infants....

  7. Changes in haematology, plasma biochemistry and erythrocyte ...

    African Journals Online (AJOL)

    The results suggest that maintaining wild birds in captivity for a prolonged period could be stressful as shown by the heterophil/lymphocytes ratio and reduced erythrocyte osmotic resistance, and could lead to decreases in erythrocyte parameters and muscle wasting. Keywords: Haematological parameters, erythrocyte ...

  8. Evaluation of haematological, hepatic and renal functions of ...

    African Journals Online (AJOL)

    Method: Twenty-five tanker drivers' and fifteen control subjects were randomly selected based on the selection criteria of not smoking and working for minimum of 5 years as petroleum tanker driver. The liver, renal and haematological parameters were analyzed using automated clinical and haematological analyzers while ...

  9. Haematological profiles and serum lead levels in male fuel ...

    African Journals Online (AJOL)

    The haematological profiles and serum lead levels of male fuel station attendants in Calabar metropolis were determined. The haematological parameters assessed included haemoglobin concentration (Hb), haematocrit (HCT), total white blood cell count (WBC), differential white cell counts and platelet count. Age range of ...

  10. In-vivo study for anti-hyperglycemic potential of aqueous extract of Basil seeds (Ocimum basilicum Linn) and its influence on biochemical parameters, serum electrolytes and haematological indices.

    Science.gov (United States)

    Chaudhary, Sachin; Semwal, Amit; Kumar, Hitesh; Verma, Harish Chandra; Kumar, Amit

    2016-12-01

    The study introduced anti-hyperglycemic influence of aqueous extract of Ocimum basilicum seeds (AEOBS) in Streptozotocin (STZ) induced diabetic rats and estimating its potential to ameliorate altered level of biochemical parameters, serum electrolytes level and haematological indices along with its effect on body weight of treated rats. The albino rats were selected to observe oral glucose tolerance test by oral intake of aq. glucose solution (4g/kg, body weight) in normal rats and estimation of blood glucose level after administration of AEOBS at 250mg/kg, 500mg/kg and standard drug glibenclamide at 0.6mg/kg, body weight. Antidiabetic activity was evaluated in chronic study models by STZ induced diabetes in rats followed by blood glucose estimation. Chronic study model was selected to carry out further studies to evaluate the effect of AEOBS at 250mg/kg, 500mg/kg and standard drug on body weight, alterations in biochemical parameters including AST, ALT, ALP, total bilirubin and total protein, alterations in serum electrolytes like Na + , K + , Cl - , HCO 3 - along with estimation of haematological indices like red blood cells (RBC), white blood cells (WBC), hemoglobin (Hb), lymphocytes, neutrophils, eosinophils, monocytes and basophils. AEOBS significantly reduced the blood glucose level of diabetic rats at both doses. Body weight was also improved significantly. Similarly, the levels of biochemical parameters, serum electrolytes, and haematological indices were significantly ameliorated at both doses of AEOBS. The histopathological results revealed reconstitution of pancreatic islets towards normal cellular architecture in rats treated with AEOBS. The results illustrated that AEOBS have eminent antidiabetic potential in STZ effectuated diabetes in rats and can be extensively used for the treatment of diabetes mellitus-II and its associated complications including anaemia, diabetic nephropathy, liver dysfunction, and immunosuppression. Copyright © 2016 Elsevier

  11. Health Status and Measurement of Some Haematological ...

    African Journals Online (AJOL)

    Background: A good school health programme is necessary to optimize the educational opportunities and make appropriate adjustments for optimal development of the school child. This study was done to determine some haematological parameters as a correlate of health status of new entrants in two mission owned ...

  12. Serum Calcium, Inorganic Phosphates and some Haematological ...

    African Journals Online (AJOL)

    Objectives: Sickle cell disease has long been associated with bone deformities and pain. Mineral salts such as calcium and inorganic phosphate are critical in bone formation and metabolism. This investigation was designed to study the serum concentration of these minerals as well as some haematological parameters in ...

  13. Antitrypanosomal and haematological effects of selected Nigerian ...

    African Journals Online (AJOL)

    Studies to determine the effect of some Nigerian Medicinal plants on some haematological parameters of rats infected with T. b. brucei was carried out. The plants investigated and the dose levels per kilogram body weights used are fresh Momordica balsamina pulp (150mg); fresh Aloe vera pulp (1ml); aqueous extracts of ...

  14. The biomedical piglet: establishing reference intervals for haematology and clinical chemistry parameters of two age groups with and without iron supplementation.

    Science.gov (United States)

    Ventrella, Domenico; Dondi, Francesco; Barone, Francesca; Serafini, Federica; Elmi, Alberto; Giunti, Massimo; Romagnoli, Noemi; Forni, Monica; Bacci, Maria L

    2017-01-17

    The similarities between swine and humans in physiological and genomic patterns, and the great correlation in size and anatomy, make pigs extremely useful in preclinical studies. New-born piglets can represent a model for congenital and genetic diseases in new-born children. It is known that piglets may have significant differences in clinicopathological results compared to adult pigs. Therefore, adult laboratory reference intervals cannot be applied to piglets. The aim of this study was to compare haematological and chemical variables in piglets of two ages and determinate age-related reference intervals for commercial hybrid young pigs. Blood samples were collected under general anaesthesia from 130 animals divided into five- (P5) and 30- (P30) day-old piglets. Only P30 animals were treated with parenteral iron after birth. Samples were analysed using automated haematology (ADVIA 2120) and chemistry analysers, and age-related reference intervals were calculated. Significant higher values of RBC, Hb and HCT were observed in P30 animals when compared to P5, with an opposite trend for MCV. These results were associated with a reduction of the RBC regeneration process and the thrombopoietic response. The TSAT and TIBC were significantly higher in P30 compared to P5; however, piglets remained iron deficient compared to adult reference intervals reported previously. In conclusion, this paper emphasises the high variability occurring in clinicopathological variables between new-born and 30-day-old pigs, and between piglets and adult pigs. This study provides valuable reference data for piglets at precise ages and could be used in the future as historical control improving the Reduction in animal experiments, as suggested by the 3Rs principle.

  15. [b][/b]Impact of copper (Cu at the dose of 50 mg on haematological and biochemical blood parameters in turkeys, and level of Cu accumulation in the selected tissues as a source of information on product safety for consumers

    Directory of Open Access Journals (Sweden)

    Bogusław Makarski

    2014-09-01

    Full Text Available Introduction. The current state-of the art points to a positive impact of copper (Cu supplements on the general health status in poultry. Copper induces beneficial changes in the haematological and biochemical blood parameters. It also displays immunostimulating properties and helps maintain a proper microbiological balance in the digestive tract. [b]Objective[/b]. The objective of this study was to investigate the impact of Cu at the dose of 50 mg/kg BW, administered in organic and inorganic form, on the haematological and biochemical blood parameters and level of Cu bioaccumulation in the liver and pectoral muscle. [b]Materials and method[/b]. The study was carried out on 45 BUT-9 turkeys which had been were reared for 16 weeks. They were divided into 3 experimental groups: I – the control group; II – fed with CuSO[sub]4[/sub] at the dose of 50 mg Cu•dm [sup]-3 [/sup]H[sub]2[/sub]O; III – received a Cu chelate with lysine at the same dose. [b]Results[/b]. The administration of Cu at the dose exceeding the nutritional recommendations did not induce beneficial changes in the examined birds. This indicates that it is not necessary to administer Cu doses higher than the recommended levels. The extent of Cu accumulation in the pectoral muscle increased by 40% compared to the control group, whereas in the liver it was higher by 30–35% than in the birds without Cu administration. The level of Cu in tissues does not pose a risk to consumers. [b]Conclusions[/b]. The supplementation of Cu at the dose of 50 mg has a negative impact on the level of the analyzed parameters. The results of the presented study indicate that the administered Cu dose exceeds birds’ demand for this element.

  16. Haematological and Serum Biochemical Parameters of Broiler Chickens Fed Varying Dietary Levels of Fermented Castor Oil Seed Meal (Ricinus communis L. and Different Methionine Sources in South Western Nigeria

    Directory of Open Access Journals (Sweden)

    Ayorinde David Adeniran

    2017-09-01

    Full Text Available In this experiment, the effect of varying dietary levels of fermented castor oil seed meal (FCSM and different methionine sources (DL-methionine and herbal methionine on haematological and serum biochemical parameters of broilers. A total of 240 one-day-old Anak broiler chicks were used in the experiment lasted 56 days. The dietary experiment was laid out as a completely randomized design in a 4 × 2 factorial arrangement consisting of 4 dietary levels of FCSM (0, 50, 100 and 150 g/kg and 2 methionine sources (DL-methionine and herbal methionine. The birds were weighed and randomly distributed into 8 treatments with 3 replicates of 10 birds each. During the starter phase of the experiment, haemoglobin, red blood cell count, mean corpuscular haemoglobin concentration and eosinophil counts were higher (P

  17. Clinical, ultrasonography and haematology of aglepristone-induced mid-gestation pregnancy terminations in rabbits

    Directory of Open Access Journals (Sweden)

    Gözde R. Özalp

    2013-05-01

    Full Text Available Aglepristone is a safe abortifacient in cats, dogs and rabbits. Although no serious side effects have been reported, there is no information available about the effects of the medicine on haematological parameters. For the first time clinical and ultrasonographic features and haematological profiles were evaluated in rabbits treated with aglepristone 15 and 16 days after mating. Ten healthy 10–14 month-old New Zealand White female rabbits were mated with fertile bucks and pregnancies were confirmed by ultrasound 15 days later. Of these, 5 does were treated with aglepristone (test group, n = 5 whilst the remaining five (control group, n = 5 were treated with a saline solution (0.9% NaCl. The treatment dose was 10 mg⁄kg body weight, administered subcutaneously once daily on two consecutive days (day 15 and 16 post mating. Ultrasonographic, clinical and haematological assessments were performed daily. Aglepristone treatment induced embryonic fluid resorptions without foetal death in mid-gestation terminations. Following ultrasonographic and haematological examinations, it was established that aglepristone is a safe abortifacient in rabbits.

  18. Child haematological malignancies

    International Nuclear Information System (INIS)

    Bertrand, Yves

    2016-01-01

    As haematological malignancies represent about 40 per cent of cancers before 15 years of age, and as the international classification makes the distinction between syndromes and leukaemia on the one hand, and lymphomas and neoplasms on the other hand, this document first briefly discuss epidemiological data on these both types of cancer, and then the various environmental risk factors: ionizing radiations, non ionizing radiations, exposure to radon, exposure to pesticides, and other exposures. It finally evokes recent evolutions related to the existence of national paediatric records, and to planned or current epidemiological studies

  19. Performance parameters of a standalone PV plant

    International Nuclear Information System (INIS)

    El Fathi, Amine; Nkhaili, Lahcen; Bennouna, Amin; Outzourhit, Abdelkader

    2014-01-01

    Highlights: • We described in details a photovoltaic power plant installed in the remote rural village Elkaria (Essaouira Morocco – 7.2 kWp). • We presented the results of monitoring and some performance parameters of the plant such as load curve. • We discussed the energy management of the plant which is based on the droop mode control. • We presented and discussed the yields and the performance ratio of the plant. - Abstract: In this work we present a detailed description of a 7.2 kWp photovoltaic power plant installed in the remote rural village Elkaria (province of Essaouira in Morocco). This plant supplies 16 households with electricity through a local grid that was installed for this purpose. The results of monitoring some performance parameters of the plant such as load curve, the yields and the performance ratio are presented and discussed. The performance ratio of the PV plant varied between 33% and 70.2%. The low values of this parameter are mainly attributed to the way the battery inverter manages the energy flow

  20. Haematological and electrocardiographic variations during menstrual cycle

    International Nuclear Information System (INIS)

    Rajnee, A.; Binawara, B.K.; Choudhary, S.; Chawla, V.K.; Choudhary, R.

    2010-01-01

    Menstruation coupled periodic bleeding from the blood vessels, at the time of shedding of the uterine mucosa has directed interest, more especially in the haematological changes during different phases of menstrual cycle. Methods: The present study was carried out on 30 healthy female medical students in the age group of 18 to 23 years with the normal menstrual cycle of 30 +- 3 days. The various haematological parameter and electrocardiography were studied on the second, eleventh, fourteenth and twenty second day of menstrual cycle. Result: The study reveals that the total leukocyte count and total platelet count significantly increased (p<0.001) around mid cycle, however total eosinophil count significantly decreased (p<0.05) during the same period. Differential leukocyte count, bleeding time, clotting time, heart rate, P-R interval and Q-T interval did not show any significant change during different phases of menstrual cycle, although some mild changes were observed. Conclusion: This study was a moderate attempt to determine regular variation in the different haematological parameters and ECG during the different phases of menstrual cycle in normal healthy females and evaluate conflicting reports on the subjects. (author)

  1. Estimating reliable paediatric reference intervals in clinical chemistry and haematology.

    Science.gov (United States)

    Ridefelt, Peter; Hellberg, Dan; Aldrimer, Mattias; Gustafsson, Jan

    2014-01-01

    Very few high-quality studies on paediatric reference intervals for general clinical chemistry and haematology analytes have been performed. Three recent prospective community-based projects utilising blood samples from healthy children in Sweden, Denmark and Canada have substantially improved the situation. The present review summarises current reference interval studies for common clinical chemistry and haematology analyses. ©2013 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  2. Comparative effects of using black seed (Nigella sativa), cumin seed (Cuminum cyminum), probiotic or prebiotic on growth performance, blood haematology and serum biochemistry of broiler chicks.

    Science.gov (United States)

    Alimohamadi, K; Taherpour, K; Ghasemi, H A; Fatahnia, F

    2014-06-01

    A 42-day trial was conducted to compare the effects of the following seven experimental diets, which varied in black seed, cumin seed, probiotic or prebiotic concentrations, on the broiler chicks: control (no additives), diet BS1 (4 g/kg black seed), diet BS2 (8 g/kg black seed), diet CS1 (4 g/kg cumin seed), diet CS2 (8 g/kg cumin seed), diet Pro (1 g/kg probiotic Primalac(®)) and diet Pre (2 g/kg prebiotic Fermacto(®)). A total of 420 1-day-old male broiler chicks, initially weighing an average of 43 g, were distributed into 28 floor pens at a stocking density of 15 birds per pen. At 28 day of age, the body weight in the birds fed diets BS2, CS2 and Pro was significantly higher than in the control group, but final body weight was not affected. Additionally, the birds fed diets BS2, Pro and Pre exhibited better feed conversion ratio than control birds from 0 to 42 day of age. Diets BS2, CS2 and Pro also statistically increased the relative weight of thymus and bursa of Fabricius, whereas only diet Pro decreased the abdominal fat percentage compared with control diet. Regarding the haematological parameters, feeding diet BS2 yielded a significant increase in red blood cell count, haemoglobin concentration and haematocrit percentage compared with control diet. Serum total cholesterol and low-density lipoprotein cholesterol levels in the birds fed diets BS2, Pro and Pre were also significantly lower than in the birds fed the control diet. Without exception, no diets affected feed intake, internal organs weights, carcass characteristics, antibody titres against Newcastle and influenza viruses and leucocyte subsets. In general, current study showed promising results regarding the use of spice additives as growth and health promoters, especially at higher levels of their incorporation in the diets, which were comparable to the probiotic- or prebiotic-containing diets. Journal of Animal Physiology and Animal Nutrition © 2013 Blackwell Verlag GmbH.

  3. A molecular and haematological study of Theileria equi in Balkan donkeys.

    Science.gov (United States)

    Davitkov, Dajana; Davitkov, Darko; Vucicevic, Milos; Stanisic, Ljubodrag; Radakovic, Milena; Glavinic, Uros; Stanimirovic, Zoran

    2017-06-01

    Equine piroplasmosis in donkeys has been recognised as a serious problem of major economic importance. The present molecular study is the first investigation of the presence of Theileria equi and Babesia caballi in Balkan donkeys and of the possible haematological alterations related to it. A total of 70 apparently healthy donkeys from Serbia were included in this study. The overall prevalence of T. equi infection in donkeys tested with multiplex PCR was 50%. There was no B. caballi-positive sample. Infections in donkeys included in this study seem to be associated with decreased red blood cell count, haemoglobin concentration, haematocrit and platelet count, and with increased white blood cell count, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration. Altered haematological parameters in donkeys can lead to a decrease in working capacity and production performance. Further molecular research and long-term monitoring of equine piroplasmosis is needed in Serbia and throughout Europe.

  4. Influence of esterified-glucomannan on performance and organ morphology, serum biochemistry and haematology in broilers exposed to individual and combined mycotoxicosis (aflatoxin, ochratoxin and T-2 toxin).

    Science.gov (United States)

    Raju, M V; Devegowda, G

    2000-12-01

    1. A study was conducted to evaluate the individual and combined effects of aflatoxin B1 (AF), ochratoxin A (OA) and T-2 toxin (T-2) on performance, organ morphology serum biochemistry and haematology of broiler chickens and the efficacy of esterified-glucomannan (E-GM), a cell wall derivative of Saccharomyces cerevisiae1026 in their counteraction. 2. Two dietary inclusion rates of AF (0 and 0.3 mg/kg), OA (0 and 2 mg/kg), T-2 (0 and 3 mg/kg) and E-GM (0 and 1 g/kg) were tested in a 2 x 2 x 2 x 2 factorial manner on a total of 960 broiler chickens from 1 to 35 d of age in an open sided deep litter pen house. 3. Body weight and food intake were depressed by all the mycotoxins, OA being the most toxic during early life. 4. Weights of kidney and adrenals were increased by AF and OA. Liver weight was increased by AF (17.8%), while OA increased gizzard weight (14.6%) and reduced bone ash content (8.1%). T-2 toxin showed no effect on these variables. 5. Serum cholesterol content was decreased and activity of serum gamma glutamyl transferase (GGT) was increased by AF and OA while serum protein content was decreased by AF. These effects were more pronounced at 21 d than at 35 d of age. Inconsistent responses were seen in the other variables: blood urea nitrogen (BUN) content, activities of serum alanine amino transferase and aspertate amino transferase. Blood haemoglobin content was depressed by AF and T-2, whereas blood coagulation time was prolonged by OA. 6. Significant interactions were observed between any 2 toxins for their additive effects on body weight, food intake, bone ash content and serum GGT activity at 21 d. Conversely, antagonistic interactions were observed among any 2 of the toxins for their effects on variables such as serum protein and serum cholesterol content. Simultaneous feeding of all 3 mycotoxins did not show increased toxicity above that seen with any 2. 7. Esterified-glucomannan increased body weight (2.26%) and food intake (1.6%), decreased

  5. Manual on radiation haematology

    International Nuclear Information System (INIS)

    1971-01-01

    Studies of the biological effects of ionizing radiation have led to the introduction of various measures to protect both the public and personnel engaged in occupations where they could be exposed to such radiations. Many recent studies deal with the basic mechanism of radiation injuries and with their treatment, and some of these investigations have been sponsored by the World Health Organization and the International Atomic Energy Agency. Fundamental studies of the blood-forming tissue have provided the information necessary for formulating recommendations of the International Commission on Radiological Protection. Heinecke in 1903 was the first to note damage to the haemato-poietic tissue after whole-body irradiation. Since that time we have learned much of the functions of the various components of the blood. Many studies have been undertaken to understand the proliferative capacities of the various 'stem' cells involved in the haematopoietic processes and the extent to which these processes can be interfered with by ionizing radiations. We now understand which are the reliable criteria by which radiation damage can be assessed from its effects on the haematopoietic system. In addition, much work has been done to determine how radiation injury to the hematopoietic system may be offset by therapy. In developing countries radiation is being increasingly applied in medical work and many other fields, and there is an immediate need to disseminate information relevant to radiation hazards. This Manual on Radiation Haematology is an attempt at a synthesis of much that is relevant to these matters. As the Contents List shows, many experts have contributed to the book. Their styles have been changed as little as possible. A certain amount of duplication of information could not be avoided; where an editorial decision to remove a passage would have resulted in losing the exact concept that the author wished to express, this passage has been retained. Information from

  6. Haematological manifestations of lupus

    Science.gov (United States)

    Fayyaz, Anum; Igoe, Ann; Kurien, Biji T; Danda, Debashish; James, Judith A; Stafford, Haraldine A; Scofield, R Hal

    2015-01-01

    Our purpose was to compile information on the haematological manifestations of systemic lupus erythematosus (SLE), namely leucopenia, lymphopenia, thrombocytopenia, autoimmune haemolytic anaemia (AIHA), thrombotic thrombocytopenic purpura (TTP) and myelofibrosis. During our search of the English-language MEDLINE sources, we did not place a date-of-publication constraint. Hence, we have reviewed previous as well as most recent studies with the subject heading SLE in combination with each manifestation. Neutropenia can lead to morbidity and mortality from increased susceptibility to infection. Severe neutropenia can be successfully treated with granulocyte colony-stimulating factor. While related to disease activity, there is no specific therapy for lymphopenia. Severe lymphopenia may require the use of prophylactic therapy to prevent select opportunistic infections. Isolated idiopathic thrombocytopenic purpura maybe the first manifestation of SLE by months or even years. Some manifestations of lupus occur more frequently in association with low platelet count in these patients, for example, neuropsychiatric manifestation, haemolytic anaemia, the antiphospholipid syndrome and renal disease. Thrombocytopenia can be regarded as an important prognostic indicator of survival in patients with SLE. Medical, surgical and biological treatment modalities are reviewed for this manifestation. First-line therapy remains glucocorticoids. Through our review, we conclude glucocorticoids do produce a response in majority of patients initially, but sustained response to therapy is unlikely. Glucocorticoids are used as first-line therapy in patients with SLE with AIHA, but there is no conclusive evidence to guide second-line therapy. Rituximab is promising in refractory and non-responding AIHA. TTP is not recognised as a criteria for classification of SLE, but there is a considerable overlap between the presenting features of TTP and SLE, and a few patients with SLE have concurrent

  7. High-altitude haematology: Quechua-Aymara comparisons.

    Science.gov (United States)

    Arnaud, J; Quilici, J C; Rivière, G

    1981-01-01

    Haematological studies have been carried out at various altitudes between 450 m and 4800 m, on two separate human groups (Quechuas and Aymaras) living in South America. Changes in the haematological parameters do not develop linearly in relation to the attitude. Th impact of chronic hypoxia on erythropoiesis is greater above 3000 m. The haemogram varies quantitatively and not qualitatively (mean corpuscular volume and mean haemoglobin concentration remain constant). The haematological study also reveals the greater adaptability to high altitude of the Aymaras, an adaptability characterized by an increase in red cell count and concentration and a decrease in red cell volume. The adaptative phenomena observed in the Quechuas are reversible, whereas they persist in the Aymaras when they migrate to the lowlands (450 m).

  8. biochemical and haematological findings in alcohol consumers in Ile

    African Journals Online (AJOL)

    Administrator

    Effect of drinking patterns on biochemical and haematological parameters was conducted on ... disease depends on a variety of factors, including genetic ... by cirrhosis, cancer and violent deaths. .... (1985) stated that the marked influence of alcohol ... The relationship between alcohol consumption, health indicators and.

  9. Haematological effects of aqueous extract of Hibiscus Sabdariffa

    African Journals Online (AJOL)

    The present study was undertaken to investigate the effects of aqueous extract of Hibiscus sabdariffa petals on some haematological parameters. The extract was administered orally in doses of 0.5, 1.0 and 1.5mg/kg body weight to normal Wistar rats for 21 days. The results showed that the extract decreased significantly (p ...

  10. Haematological and sperm count changes following Exposure to ...

    African Journals Online (AJOL)

    The plants Hyptis suaveolens, Clome viscosa and Urena lobata are herbs commonly found growing in pasture and also used as medicinal plant in Nigeria. They were suspected to be toxic following a pilot toxicity study, and their toxic effects were thus evaluated on haematological parameters and sperm count of albino rats.

  11. Haematology and faecal parasitic load of West African Dwarf goats ...

    African Journals Online (AJOL)

    Haematology and faecal parasitic load of West African Dwarf goats fed Panicum maximum supplemented with wheat offal. ... Total White Blood Cell (TWBC), L and N. There was an increased post-trial hematological over pre-trial hematological parameters for PCV, N and M while a decrease was observed for L in animals ...

  12. Effects of Crude Extracts of Portulaca oleracea on Haematological ...

    African Journals Online (AJOL)

    The effects of oral administration of aqueous (AEPO) and methanolic (MEPO) extracts of Portulaca oleracea at various doses (25mg/kg BW, 50mg/kgBW and 75mg/kgBW) on haematological and plasma biochemical parameters of albino rats were investigated. The extracts were administered on daily basis for 30 days and ...

  13. Haematological reference values for healthy adults in Port Harcourt ...

    African Journals Online (AJOL)

    The following haematological parameters were determined by the indicated methods: haematocrit (Hct) was determined using Hawksley micro-capillary centrifugation, haemoglobin concentration (Hbc) was determined using the cyanmethaemoglobin method, red blood cell count and white blood cell count were both ...

  14. A Survey Of Normal Haematological Variables Among Adults In ...

    African Journals Online (AJOL)

    Main outcome measures: Haematological values of the following blood parameters were determined; Haemoglobin (Hb), Haematocrit(PCV), Erythrocyte (RBC) count, Leucocyte (WBC) count, Platelet count and the differential cells count (consisting of the Neutrophils, Eosinophils, Basophiles, Lymphocytes and Monocyte ...

  15. Effect of pineapple (Ananas comosus) on haematological and ...

    African Journals Online (AJOL)

    Administrator

    2011-06-20

    Jun 20, 2011 ... Full Length Research Paper ... The aim of this study is to evaluate the liver's protection of Ananas comosus on albinos Wistar rats .... Haematological parameters of Wistar rats intoxicated with Doliprane® and treated with stem of A. comosus. ... Treatment CGMH (103/mm3 of blood) TGMH (pg/ blood cell).

  16. Haematological and biochemical evaluation of the n -hexane extract ...

    African Journals Online (AJOL)

    The study undertook to evaluate the sub-chronic toxicological profile of the seed of Ricinus communis var. minor (RICOM-1013-J), widely used as anticonceptive agent among Bassa people of Plateau State, Nigeria, on haematological and biochemical parameters in adult rats. Thirty-six (36) adult female rats were divided ...

  17. Meditation for adults with haematological malignancies.

    Science.gov (United States)

    Salhofer, Ines; Will, Andrea; Monsef, Ina; Skoetz, Nicole

    2016-02-03

    information provided about the average age and sex of the study population. We found a high risk for attrition bias and unclear risk for reporting bias, performance and detection bias because of missing data due to abstract publication only, thus we judged the overall risk of bias as high. According to the GRADE criteria, we judged the overall quality of the body of evidence for all predefined outcomes as 'very low', due to the extent of missing data on the study population, and the small sample size.As the abstract publication did not provide numbers and results except P values, we are not able to give more details.Meditation practice might be beneficial for the quality of life of haematologically-diseased patients, with higher scores for participants in the mediation arms compared to the participants in the usual care control group (low quality of evidence). Levels of depression decreased for those practising meditation in both the spiritually-framed meditation group and the secularly-focused meditation group in comparison to the usual care control group, whose levels of depression remained constant (low quality of evidence). The influence of meditation practice on overall survival, fatigue, anxiety, quality of sleep and adverse events remained unclear, as these outcomes were not evaluated in the included trial. To estimate the effects of meditation practice for patients suffering from haematological malignancies, more high quality randomised controlled trials are needed. At present there is not enough information available on the effects of meditation in haematologically-diseased patients to draw any conclusion.

  18. Influência de diferentes níveis de vitamina C na ração sobre parâmetros hematológicos de alevinos de Piaractus mesopotamicus Holmberg (Osteichthyes, Characidae Influence of different levels of vitamin C in the ration on the haematological parameters of Piaractus mesopotamicus Holmberg (Osteichthyes, Characidae fries

    Directory of Open Access Journals (Sweden)

    Maurício Laterça Martins

    1995-09-01

    Full Text Available Haematological changes in ascorbic acid deficient fishes, observed by some authors, awoked the interest in the haematological response of pacu, Piaractus mesopotamicus. The present work studied the influence of different levels of ascorbic acid (vitamin C in the ration on the haematological parameters of pacu. Fishes at the beginning of the experiment, presented average body weight 8.64±1.62g and 6.15±0.33cm standard length, were fed with diets containing 0. 50, 100 and 200mg ascorbic acid/kg dry ration. The present work was developed for a period of 24 weeks at the Fish Nutrition Laboratory of Aquaculture Center of Universidade Estadual Paulista (Unesp, Jaboticabal (São Paulo. The fishes were distributed by the completely randomized design in 20 aquaria of 100 liters capacity with six animals in each and five fold treatment. Condutivity, alcalinity. pH and oxigen were measured weekly and temperature daily. The blood colect was done in 60 anesthetized fishes with 50mg MS-222/1. The results suggests that 50mg ascorbic acid/kg dry ration improved the mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration and decreased haematocril in unsupplemented fishes, although not differing significantly (P>0.05. The erytrocyte diameter indicated the presence of macrocytic cells in unsupplemented fishes (P<0.05 and the regression analysis showed too reduced neutrophils in unsupplemenled ones, 50mg ascorbic acid/kg dry ration supplementation was enough to development and haematological responses. Furthtermore, the optimum level to the growth is 139mg vitamin C/kg dry ration (P<0.05.

  19. determination of some haematological parameters in malaria

    African Journals Online (AJOL)

    USER

    2015-06-01

    Jun 1, 2015 ... Bayero Journal of Pure and Applied Sciences, 8(1): 80 – 83. Received: April ... INFECTED SUBJECTS IN USMANU DANFODIYO UNIVERSITY TEACHING. HOSPITAL ... genus contains over 125 species that cause malaria.

  20. Evaluation of Haematological and Biochemical Parameters of ...

    African Journals Online (AJOL)

    ADOWIE PERE

    Keywords: Crude oil, Afiesere oil field, blood, toxicity, water quality, Oreochromis niloticus. Crude oil exploration and ..... impaired kidney function, liver diseases and cardiac ... moench on acetaminophen-induced hepatoxicity in mice. AM.J. Uin ...

  1. Haematological parameters and recurrent aphthous stomatitis

    International Nuclear Information System (INIS)

    Khan, N. F.; Saeed, M.; Chaudhary, S.

    2013-01-01

    Objective: To find out the relationship between recurrent aphthous stomatitis (RAS) with deficiencies of haemoglobin, haematocrit, serum vitamin B12, serum Ferritin and red blood cells (RBC) Folate level. Study Design: An analytical cross-sectional study. Place and Duration of Study: Department of Oral Health Sciences, Shaikh Zayed Federal Postgraduate Medical Complex, Lahore, from February to July 2008. Methodology: Sixty consecutive subjects with active RAS were taken as the aphthous group; 60 age and gender matched subjects without RAS were as the Non-Aphthous group. Five milliliter blood was taken from both groups to evaluate the levels of serum B12, and RBC Folate through radio immuno assay and serum ferritin with enzyme linked immuno-sorbent assay tests. Complete blood count was carried out to determine the level of haemoglobin and haematocrit in both groups. Proportion of subjects with lower values was compared using 2 text of proportions with significance at p < 0.05. Results: Serum Ferritin (p = 0.001), haematocrit (p < 0.001), RBC Folate (p < 0.001) and serum B12 (p < 0.001) were significantly lower in the RAS group. Combined deficiency state (haemoglobin, serum Ferritin, haematocrit, RBC Folate and serum B12) was identified in 13% (n = 8) RAS patients. Conclusion: Frequency of haematinic deficiencies was high in RAS patients. Serum B12 and RBC Folate were significantly low in aphthous group. (author)

  2. Haematological parameters in systemic lupus erythematosus ...

    African Journals Online (AJOL)

    Design: Cross-sectional hospital based descriptive study. Setting: Rheumatology out-patient clinic and Renal out-patient clinic at KNH. Subjects: Sixty five patients who fulfilled the 1997 American College of Rheumatology Classification Criteria for SLE. Results: Sixty five eligible SLE patients were recruited into the study.

  3. Innovative haematological parameters in clinical practice

    NARCIS (Netherlands)

    Schoorl, M.

    2015-01-01

    Anaemia is a global public health problem affecting populations in both developing and developed countries. According to the World Health Organisation (WHO) anaemia affects 1.62 billion people, which corresponds to 25% of the world population. In case of anaemia microcytic erythropoiesis is

  4. Some Haematological Parameters in Posttraumatic Stress Disorder ...

    African Journals Online (AJOL)

    Posttraumatic stress disorder (PTSD) is an emotional disorder which occurs as a result of a life threatening experience. Individuals with PTSD are more likely to develop medical conditions related to stress and research has shown that they may have altered neuro endocrine and immune system abnormalities.2 Diagnosis of ...

  5. Some haematological parameters of tuberculosis infected Nigerians ...

    African Journals Online (AJOL)

    Tuberculosis is a major public health problem in Nigeria. Drug resistant tuberculosis is now common place due to poor patient compliance and lack of detection of resistant strains. The occurrence of HIV has been responsible for an increased frequency of tuberculosis. Knowledge of the blood picture in pulmonary ...

  6. BLOOD DONOR HAEMATOLOGY PARAMETERS IN TWO ...

    African Journals Online (AJOL)

    hi-tech

    2005-03-03

    Mar 3, 2005 ... determine distribution frequencies (including mean and median) and 95% percentile ranges (defined as the mean ± 2SD). These were determined individually for Kisumu and Nairobi, and comparisons between the two donor groups were made using the independent samples t-test. RESULTS. Red blood ...

  7. Changing haematological parameters in dengue viral infections

    International Nuclear Information System (INIS)

    Jamil, T.; Mehmood, K.; Mujtaba, G.; Choudhry, N.

    2012-01-01

    Background: Dengue Fever is the most common arboviral disease in the world, and presents cyclically in tropical and subtropical regions of the world. The four serotypes of dengue virus, 1, 2, 3, and 4, form an antigenic subgroup of the flaviviruses (Group B arboviruses). Transmission to humans of any of these serotypes initiates a spectrum of host responses, from in apparent to severe and sometimes lethal infections. Complete Blood count (CBC) is an important part of the diagnostic workup of patients. Comparison of various finding in CBC including peripheral smear can help the physician in better management of the patient. Material and Methods: This cross sectional study was carried out on a series of suspected patients of Dengue viral infection reporting in Ittefaq Hospital (Trust). All were investigated for serological markers of acute infection. Results Out of 341 acute cases 166 (48.7%) were confirmed by IgM against Dengue virus. IgG anti-dengue was used on 200 suspected re-infected patients. Seventy-one (39.5%) were positive and 118 (59%) were negative. Among 245 confirmed dengue fever patients 43 (17.6%) were considered having dengue hemorrhagic fever on the basis of lab and clinical findings. Raised haematocrit, Leukopenia with relative Lymphocytosis and presence atypical lymphocytes along with plasmacytoid cells was consistent finding at presentation in both the patterns of disease, i.e., Dengue Haemorrhagic fever (DHF) and Dengue fever (DF). Conclusion: Changes in relative percentage of cells appear with improvement in the symptoms and recovery from the disease. These findings indicate that in the course of the disease, there are major shifts within cellular component of blood. (author)

  8. seed on haematological parameters of albino rats

    African Journals Online (AJOL)

    Dr Ejere

    2015-06-23

    Jun 23, 2015 ... and its indices (haemoglobin content, pack cell volume, mean corpuscular volume, mean corpuscular haemoglobin ... demands in plant-based proteins for humans and livestock, ... hypogea) and animal based proteins (Siddhuraju et al.,. 1995 ..... difference in the packed cell volume (PCV) of albino rats.

  9. Haematological malignancy in the adult

    International Nuclear Information System (INIS)

    Mair, G.

    1986-01-01

    The emphasis in this chapter has been placed on those aspects of treatment of the following haematological malignancies of particular relevance to the radiotherapist: acute lymphoblastic leukemia, acute non-lymphocytic leukemia, chronic granulocytic leukemia, chronic lymphocytic leukemia extramedullary leukemic deposits, granulocytic sarcoma, polycythaemia rubra vera, myelofibrosis, multiple myeloma, solitary plasmacytoma. (U.K.)

  10. 233 Haematological Characteristics and Blood

    African Journals Online (AJOL)

    2008-12-02

    Dec 2, 2008 ... nitrogen of Sokoto Red kids fed varying levels of Fore-stomach digesta (FSD) replacing cowpea husk at 0, 10, 20 and 30 ... Haematological Characteristics and Blood Urea Nitrogen of Sokoto Red Goat Kids Fed …… 228. Formulation of ..... significant rise in Hb level in treatment D. This is an indication that ...

  11. Eye involvement in haematological malignancies

    NARCIS (Netherlands)

    Riemens, J.A.

    2014-01-01

    This thesis describes the involvement of the eye in haematological malignancies and focuses on two topics; primary vitreoretinal lymphoma (PVRL) and ocular Graft-versus-Host Disease (GvHD). The aim of this thesis is first: to compare the efficacy of diverse treatment options of PVRL with regard to

  12. Admission haematological abnormalities and postoperative ...

    African Journals Online (AJOL)

    Admission haematological abnormalities and postoperative outcomes in neonates with acute surgical conditions in Alexandria, Egypt. HL Wella, SMM Farahat. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals ...

  13. Performance parameters of electric power distribution

    International Nuclear Information System (INIS)

    Schilling, M.Th.; Lima, J.W.M.

    1992-01-01

    The aspects referring to the evaluation of distribution system reliability are presented: consumers, companies and regulator institutes. The different strategies for fixing of probabilistic criterions of performance are mentioned, including the economic valorization of continuity restriction of electric supply. (C.G.C.)

  14. Parameters for screening music performance anxiety

    OpenAIRE

    Barbar, Ana E.; Crippa, José A.; Osório, Flávia L.

    2014-01-01

    Objective: To assess the discriminative capacity of the Kenny Music Performance Anxiety Inventory (K-MPAI), in its version adapted for Brazil, in a sample of 230 Brazilian adult musicians. Method: The Social Phobia Inventory (SPIN) was used to assess the presence of social anxiety indicators, adopting it as the gold standard. The Mann-Whitney U test and the receiver operating characteristic (ROC) curve were used for statistical analysis, with p ≤ 0.05 set as the significance level. ...

  15. Parameters for screening music performance anxiety.

    Science.gov (United States)

    Barbar, Ana E; Crippa, José A; Osório, Flávia L

    2014-09-01

    To assess the discriminative capacity of the Kenny Music Performance Anxiety Inventory (K-MPAI), in its version adapted for Brazil, in a sample of 230 Brazilian adult musicians. The Social Phobia Inventory (SPIN) was used to assess the presence of social anxiety indicators, adopting it as the gold standard. The Mann-Whitney U test and the receiver operating characteristic (ROC) curve were used for statistical analysis, with p ≤ 0.05 set as the significance level. Subjects with social anxiety indicators exhibited higher mean total K-MPAI scores, as well as higher individual scores on 62% of its items. The area under the ROC curve was 0.734 (p = 0.001), and considered appropriate. Within the possible cutoff scores presented, the score -15 had the best balance of sensitivity and specificity values. However, the score -7 had greater specificity and accuracy. The K-MPAI showed appropriate discriminant validity, with a marked association between music performance anxiety and social anxiety. The cutoff scores presented in the study have both clinical and research value, allowing screening for music performance anxiety and identification of possible cases.

  16. Parameters for screening music performance anxiety

    Directory of Open Access Journals (Sweden)

    Ana E. Barbar

    2014-09-01

    Full Text Available Objective: To assess the discriminative capacity of the Kenny Music Performance Anxiety Inventory (K-MPAI, in its version adapted for Brazil, in a sample of 230 Brazilian adult musicians. Method: The Social Phobia Inventory (SPIN was used to assess the presence of social anxiety indicators, adopting it as the gold standard. The Mann-Whitney U test and the receiver operating characteristic (ROC curve were used for statistical analysis, with p ≤ 0.05 set as the significance level. Results: Subjects with social anxiety indicators exhibited higher mean total K-MPAI scores, as well as higher individual scores on 62% of its items. The area under the ROC curve was 0.734 (p = 0.001, and considered appropriate. Within the possible cutoff scores presented, the score -15 had the best balance of sensitivity and specificity values. However, the score -7 had greater specificity and accuracy. Conclusion: The K-MPAI showed appropriate discriminant validity, with a marked association between music performance anxiety and social anxiety. The cutoff scores presented in the study have both clinical and research value, allowing screening for music performance anxiety and identification of possible cases.

  17. Performance Parameters for Grid-Connected PV Systems

    Energy Technology Data Exchange (ETDEWEB)

    Marion, B.; Adelstein, J.; Boyle, K.; Hayden, H.; Hammond, B.; Fletcher, T.; Canada, B.; Narang, D.; Shugar, D.; Wenger, H.; Kimber, A.; Mitchell, L.; Rich, G.; Townsend, T.

    2005-02-01

    The use of appropriate performance parameters facilitates the comparison of grid-connected photovoltaic (PV) systems that may differ with respect to design, technology, or geographic location. Four performance parameters that define the overall system performance with respect to the energy production, solar resource, and overall effect of system losses are the following: final PV system yield, reference yield, performance ratio, and PVUSA rating. These performance parameters are discussed for their suitability in providing desired information for PV system design and performance evaluation and are demonstrated for a variety of technologies, designs, and geographic locations. Also discussed are methodologies for determining system a.c. power ratings in the design phase using multipliers developed from measured performance parameters.The use of appropriate performance parameters facilitates the comparison of grid-connected photovoltaic (PV) systems that may differ with respect to design, technology, or geographic location. Four performance parameters that define the overall system performance with respect to the energy production, solar resource, and overall effect of system losses are the following: final PV system yield, reference yield, performance ratio, and PVUSA rating. These performance parameters are discussed for their suitability in providing desired information for PV system design and performance evaluation and are demonstrated for a variety of technologies, designs, and geographic locations. Also discussed are methodologies for determining system a.c. power ratings in the design phase using multipliers developed from measured performance parameters.

  18. Improving the performance parameters of metal cylindrical grid shell ...

    African Journals Online (AJOL)

    Improving the performance parameters of metal cylindrical grid shell structures. ... Finite element models are designed taking into account minimization of production and ... The force factors and deformation parameters of the basic circuits of a ...

  19. Performance parameters for ex situ bioremediation systems

    International Nuclear Information System (INIS)

    Wade, D.R.

    1994-01-01

    The potential of biotechnology to reduce the concentration of undesirable hydrocarbons, i.e. gasoline and diesel fuel pollution, is very attractive due to its apparent benign nature and potentially low cost. When good industrial practices are used in the design, construction, and administration of the bioremediation system, the performance of the technology can be predicted and monitored. Some of the principles behind the design, construction, and operation of ex situ bioremediation systems and facilities are described. Biological considerations include creation of a favorable environment for hydrocarbon degrading bacteria in the soils, selection of bacteria, and bacterial byproducts. Chemical considerations include nutrient augmentation, oxygen availability, and the use of surfactants and dispersants. Physical considerations include soil textures and structures, soil temperatures, moisture content, and the use of bulking agents. Experience has shown that indigenous microbes will usually be sufficient to implement bioremediation of petroleum hydrocarbons if encouraged through the application of fertilizers. The introduction of additional carbon sources may be considered if rapid bioremediation rates are desired or if soil conditions are poor. Adjustments to a bioremediation system may be made to enhance the performance of the bacterial community by introducing bulking agents and external temperature sources. Surfactants may be helpful in promoting bacteria-hydrocarbon contact and may be particularly useful for mobilization of free-phase hydrocarbons. 7 refs

  20. Concurrently adjusting interrelated control parameters to achieve optimal engine performance

    Science.gov (United States)

    Jiang, Li; Lee, Donghoon; Yilmaz, Hakan; Stefanopoulou, Anna

    2015-12-01

    Methods and systems for real-time engine control optimization are provided. A value of an engine performance variable is determined, a value of a first operating condition and a value of a second operating condition of a vehicle engine are detected, and initial values for a first engine control parameter and a second engine control parameter are determined based on the detected first operating condition and the detected second operating condition. The initial values for the first engine control parameter and the second engine control parameter are adjusted based on the determined value of the engine performance variable to cause the engine performance variable to approach a target engine performance variable. In order to cause the engine performance variable to approach the target engine performance variable, adjusting the initial value for the first engine control parameter necessitates a corresponding adjustment of the initial value for the second engine control parameter.

  1. Identifying the connective strength between model parameters and performance criteria

    Directory of Open Access Journals (Sweden)

    B. Guse

    2017-11-01

    Full Text Available In hydrological models, parameters are used to represent the time-invariant characteristics of catchments and to capture different aspects of hydrological response. Hence, model parameters need to be identified based on their role in controlling the hydrological behaviour. For the identification of meaningful parameter values, multiple and complementary performance criteria are used that compare modelled and measured discharge time series. The reliability of the identification of hydrologically meaningful model parameter values depends on how distinctly a model parameter can be assigned to one of the performance criteria. To investigate this, we introduce the new concept of connective strength between model parameters and performance criteria. The connective strength assesses the intensity in the interrelationship between model parameters and performance criteria in a bijective way. In our analysis of connective strength, model simulations are carried out based on a latin hypercube sampling. Ten performance criteria including Nash–Sutcliffe efficiency (NSE, Kling–Gupta efficiency (KGE and its three components (alpha, beta and r as well as RSR (the ratio of the root mean square error to the standard deviation for different segments of the flow duration curve (FDC are calculated. With a joint analysis of two regression tree (RT approaches, we derive how a model parameter is connected to different performance criteria. At first, RTs are constructed using each performance criterion as the target variable to detect the most relevant model parameters for each performance criterion. Secondly, RTs are constructed using each parameter as the target variable to detect which performance criteria are impacted by changes in the values of one distinct model parameter. Based on this, appropriate performance criteria are identified for each model parameter. In this study, a high bijective connective strength between model parameters and performance criteria

  2. Calculation of driling and blasting parameters in blasting performance

    OpenAIRE

    Dambov, Risto; Karanakova Stefanovska, Radmila; Dambov, Ilija

    2015-01-01

    In all mining technology drilling and blasting parameters and works are one of the main production processes at each mine. The parameters of drilling and blasting and explosives consumption per ton of blasting mass are define economic indicators of any blasting no matter for what purpose and where mining is performed. The calculation of rock blasting should always have in mind that the methodology of calculation of all drilling and blasting parameters in blasting performance are performed for...

  3. Amphibian haematology: Metamorphosis-related changes in blood cells

    DEFF Research Database (Denmark)

    Rosenkilde, Per; Sørensen, Inger; Ussing, Anne Phaff

    1995-01-01

    Zoofysiologi, Amphibian metamorphosis, Haematology, Immunosuppression, Immunological Tolerance, Protozoan Infection, metamorfose, springpadder, ontogenese, halepadder.......Zoofysiologi, Amphibian metamorphosis, Haematology, Immunosuppression, Immunological Tolerance, Protozoan Infection, metamorfose, springpadder, ontogenese, halepadder....

  4. Hormonal and haematological responses of Clarias gariepinus ...

    African Journals Online (AJOL)

    This study assessed hormonal and haematological responses of Clarias gariepinus to ammonia toxicity. Laboratory study of haematological responses of adult C. gariepinus to sub-lethal level of ammonia (2.2 g/l) at different exposure hours (0, 6, 24, 48, 72, 96 h) were carried out. Blood samples of C. gariepinus were ...

  5. Haematological Problems Associated with Gaucher's Disease ...

    African Journals Online (AJOL)

    Five recent cases of Gaucher's disease seen at Groote Schuur Hospital illustrate the haematological complications. The main problem is hypersplenism with secondary thrombocytopenia. Two patients underwent splenectomy for this reason, and one gained lasting improvement. None of the more rare haematological ...

  6. Performance of a solar chimney by varying design parameters

    CSIR Research Space (South Africa)

    Kumirai, T

    2015-08-01

    Full Text Available the design of solar chimneys to ensure optimal performance. The purpose of this chapter is to discuss the performance of an example solar chimney by varying the design parameters and examining their effects on the interior ventilation performance... chimney by varying design parameters Tichaona Kumirai, Researcher, Built Environment CSIR Jan-Hendrik Grobler, DPSS CSIR Dr D.C.U. Conradie, Senior researcher, Built Environment CSIR 1 Introduction Trombe walls and solar chimneys are not widely...

  7. Distribution of haematological and chemical pathology values among infants in Malawi and Uganda

    Science.gov (United States)

    Kumwenda, Newton I.; Khonje, Tiwonge; Mipando, Linda; Nkanaunena, Kondwani; Katundu, Pauline; Lubega, Irene; Elbireer, Ali; Bolton, Steve; Bagenda, Danstan; Mubiru, Michael; Fowler, Mary Glenn; Taha, Taha E.

    2013-01-01

    Background Data on paediatric reference laboratory values are limited for sub-Saharan Africa. Objective To describe the distribution of haematological and chemical pathology values among healthy infants from Malawi and Uganda. Methods A cross-sectional study was conducted among healthy infants, 0–6 months old, born to HIV-uninfected mothers recruited from two settings in Blantyre, Malawi and Kampala, Uganda. Chemical pathology and haematology parameters were determined using standard methods on blood samples. Descriptive analyses by age-group were performed based on 2004 Division of AIDS Toxicity Table age categories. Mean values and interquartile ranges were compared by site and age-group. Results A total of 541 infants were included altogether, 294 from Malawi and 247 from Uganda. Overall, the mean laboratory values were comparable between the two sites. Mean alkaline phosphatase levels were lower among infants aged ≤21 days while aspartate aminotransferase, creatinine, total bilirubin and gamma-glutamyl transferase were higher in those aged 0–7 days than in older infants. Mean haematocrit, haemoglobin and neutrophil counts were higher in the younger age-groups (<35 days) and overall were lower than US norms. Red and white blood cell counts tended to decrease after birth but increased after ~2 months of age. Mean basophil counts were higher in Malawi than in Uganda in infants aged 0–1 and 2–7 days; mean counts for eosinophils (for age groups 8–21 or older) and platelets (for all age groups) were higher in Ugandan than in Malawian infants. Absolute lymphocyte counts increased with infant age. Conclusion The chemical pathology and haematological values in healthy infants born to HIV-uninfected mothers were comparable in Malawi and Uganda and can serve as useful reference values in these settings. PMID:23164296

  8. Haematological and biochemical effects of polyphenolics in animal models.

    Science.gov (United States)

    Gnanamani, Arumugam; Sudha, Munusamy; Deepa, G; Sudha, M; Deivanai, K; Sadulla, S

    2008-07-01

    Polyphenols of natural and synthetic origin are exploited in tanning sector to convert putrescible skin/hide to non-putrescible leather. However, only 30-40% of the inputs have been taken up for processing, the remaining is released as unspent. The existing conventional wastewater treatment systems are inefficient in removing or degrading these unspent polyphenols and thus detrimental to ecosystem. The present study demonstrates the evaluation of impact of both synthetic and natural polyphenols on biochemical and haematological properties of blood and serum in animal models. The results reveal that concentrations of polyphenols play a major role. At higher concentrations, irrespective of their nature, there was a marked change in the lipid profile (81% reduction), followed by insignificant change in glucose levels, RBC and WBC counts and other haematological parameters. At lower concentrations, no significant changes in the above said properties were observed.

  9. Detection of candidaemia in patients with and without underlying haematological disease

    DEFF Research Database (Denmark)

    Arendrup, M C; Bergmann, O J; Larsson, L.

    2010-01-01

    : 100%, 73.9%. Applying the DA/LA ratio to only patients with haematological neutropenia the values were: 75%, 90.5%. Fungal blood culture allowed slightly improved detection of candidaemia. The best indirect test performance was obtained from combined mannan-Ag and anti-mannan Ab detection, especially...... with lower cut-offs. DA/LA ratio appears to be useful in the context of haematological neutropenia...

  10. Community Design Parameters and the Performance of Residential Cogeneration Systems

    Directory of Open Access Journals (Sweden)

    Hazem Rashed-Ali

    2012-11-01

    Full Text Available The integration of cogeneration systems in residential and mixed-use communities has the potential of reducing their energy demand and harmful emissions and can thus play asignificant role in increasing their environmental sustainability. This study investigated the impact of selected planning and architectural design parameters on the environmental and economic performances of centralized cogeneration systems integrated into residential communities in U.S.cold climates. Parameters investigated include: 1 density, 2 use mix, 3 street configuration, 4 housing typology, 5 envelope and building systems’ efficiencies, and 6 passive solar energyutilization. The study integrated several simulation tools into a procedure to assess the impact of each design parameter on the cogeneration system performance. This assessment procedure included: developing a base-line model representing typical design characteristics of U.S. residential communities; assessing the cogeneration system’s performance within this model using three performance indicators: percentage of reduction in primary energy use, percentage of reduction in CO2 emissions; and internal rate of return; assessing the impact of each parameter on the system performance through developing 46 design variations of the base-line model representing potential changes in each parameter and calculating the three indicators for each variation; and finally, using a multi-attribute decision analysis methodology to evaluate the relative impact of each parameter on the cogeneration system performance. The study results show that planning parameters had a higher impact on the cogeneration system performance than architectural ones. Also, a significant correlation was found between design characteristics identified as favorable for the cogeneration system performance and those of sustainable residential communities. These include high densities, high use mix, interconnected street networks, and mixing of

  11. Performance analysis of pin fins with temperature dependent thermal parameters using the variation of parameters method

    Directory of Open Access Journals (Sweden)

    Cihat Arslantürk

    2016-08-01

    Full Text Available The performance of pin fins transferring heat by convection and radiation and having variable thermal conductivity, variable emissivity and variable heat transfer coefficient was investigated in the present paper. Nondimensionalizing the fin equation, the problem parameters which affect the fin performance were obtained. Dimensionless nonlinear fin equation was solved with the variation of parameters method, which is quite new in the solution of nonlinear heat transfer problems. The solution of variation of parameters method was compared with known analytical solutions and some numerical solution. The comparisons showed that the solutions are seen to be perfectly compatible. The effects of problem parameters were investigated on the heat transfer rate and fin efficiency and results were presented graphically.

  12. HAEMATOLOGICAL INDICES AND ENZYMATIC BIOMAKER OF ...

    African Journals Online (AJOL)

    AGROSEARCH UIL

    haematological characteristics of S. melanotheron in this study. ... provide a useful tool in monitoring the condition and state of health of fish by ..... peroxidation in gonads of white suckers exposed to pulp and paper mill effluents as well as.

  13. Antibacterial and haematological activity of Moringa oleifera ...

    African Journals Online (AJOL)

    The phytochemical, antibacterial and haematologic activity of aqueous seed extract of Moringa oleifera (Moringaceae) were evaluated. Phytochemicals such as tannins, carbohydrates, alkaloids, cardiac glycosides, anthraquinones and flavonoids in low, moderate and high concentrations were present in the seeds.

  14. Antibacterial and haematological activity of Moringa oleifera ...

    African Journals Online (AJOL)

    ADEYEYE

    6Department of Human Anatomy, College of Medical Sciences, University of Maiduguri, Borno ... Keywords: Antibacterial effect, Haematology, Moringa olifera, Phytochemical analysis, Wistar albino rats. ..... Moringa oleifera: A food plant with.

  15. Experimental Studies on the Hypolipidemic and Haematological ...

    African Journals Online (AJOL)

    Uche

    2011-01-14

    Jan 14, 2011 ... lipid and haematological profile of serum and blood samples collected were determined respectively. ..... garden Egg fruit, oat and Apple on serum ... Philadelphia: W.B. Saunders Company; 1970: ... McGraw-Hill Inc; 1980; 87.

  16. Bronchoalveolar Lavage Fluid Cellular and Haematological ...

    African Journals Online (AJOL)

    olayemitoyin

    Haematological indices and BALf cells were analysed from 300 goats randomly selected from 700 goats .... MQ-N ratio macrophage:neutrophil ratio, EOS- eosinophil, MAST- Mast cells. ... are suggestive of tissue injury and or inflammation.

  17. Developing Key Parameters for Green Performance of Partition Wall Blocks

    Directory of Open Access Journals (Sweden)

    Goh Cheng Siew

    2016-01-01

    Full Text Available To promote sustainable construction, it is important to consider green performance of construction materials throughout the life cycle. Selecting inappropriate materials could not only affect the functional performance but also preclude the achievement of green building performance as a whole. Green performance of construction materials has therefore been one of the primary considerations of green building assessment systems. Using partition wall blocks as an example, this paper examines green performance of building materials primarily from the cradle to gate boundaries. Nine key parameters are proposed for the green performance of partition wall blocks. Apart from environmental features, technical performance of partition wall blocks is also taken into consideration since it is the determinant of the lifecycle performance. This paper offers a roadmap to decision makers to make environmentally responsible choices for their materials of internal walls and partitions, and hence provides a potential sustainable solution for green buildings.

  18. Distillery effluent induced alterations in the haematological profile of fingerlings of Colisa fasciatus.

    Science.gov (United States)

    Shukla, Anuradha; Shukla, J P

    2013-09-01

    Present study deals with the impact of Gorakhpur distillery effluent at various concentration levels (5, 10 and 20%) on the blood profile of fingerling of, Colisa fosciotus after 30 days of exposure. Observations revealed that 5% of effluent concentration produced no significant alterations in various haematological parameters except for clotting time and immature erythrocytes. However, 10% of effluent concentration brought significant alterations in hematocrit as well as clotting time and 20% of effluent concentration produced highly significant (P<0.001) alteration in most of the haematological parameters except for hemoglobin percentage.

  19. Effects of supervised Self Organising Maps parameters on classification performance.

    Science.gov (United States)

    Ballabio, Davide; Vasighi, Mahdi; Filzmoser, Peter

    2013-02-26

    Self Organising Maps (SOMs) are one of the most powerful learning strategies among neural networks algorithms. SOMs have several adaptable parameters and the selection of appropriate network architectures is required in order to make accurate predictions. The major disadvantage of SOMs is probably due to the network optimisation, since this procedure can be often time-expensive. Effects of network size, training epochs and learning rate on the classification performance of SOMs are known, whereas the effect of other parameters (type of SOMs, weights initialisation, training algorithm, topology and boundary conditions) are not so obvious. This study was addressed to analyse the effect of SOMs parameters on the network classification performance, as well as on their computational times, taking into consideration a significant number of real datasets, in order to achieve a comprehensive statistical comparison. Parameters were contemporaneously evaluated by means of an approach based on the design of experiments, which enabled the investigation of their interaction effects. Results highlighted the most important parameters which influence the classification performance and enabled the identification of the optimal settings, as well as the optimal architectures to reduce the computational time of SOMs. Copyright © 2012 Elsevier B.V. All rights reserved.

  20. Assessment of performance parameters for EPR dosimetry with tooth enamel

    International Nuclear Information System (INIS)

    Wieser, A.; Fattibene, P.; Shishkina, E.A.; Ivanov, D.V.; De Coste, V.; Guettler, A.; Onori, S.

    2008-01-01

    In the framework of a comparison between three laboratories, electron paramagnetic resonance (EPR) signal-to-dose response curves were measured for sets of 30 tooth enamel samples and the variance of EPR measurements in dependence on absorbed dose was evaluated, in nine combinations of laboratory of sample preparation and EPR evaluation, respectively. As a test for benchmarking of EPR evaluation, the parameters 'critical dose' and 'limit of detection' were proposed as performance parameters following definitions from chemical-metrology, and a model function was suggested for analytical formulation of the dependence of the variance of EPR measurement on absorbed dose. First estimates of limits of detection by weighted and unweighted fitting resulted in the range 101-552 and 67-561 mGy, respectively, and were generally larger with weighted than with unweighted fitting. Indication was found for the influence of methodology of sample preparation and applied EPR measurement parameters on performance of EPR dosimetry with tooth enamel

  1. Effect of Varying Controller Parameters on the Performance of a ...

    African Journals Online (AJOL)

    This paper presents the results of computer simulation studies designed to isolate the effects of the major parameters of a fuzzy logic controller namely the range of the universe of discourse, the extent of overlap of the fuzzy sets, the rules in the rule base and the modes of the output fuzzy sets on the performance of a fuzzy ...

  2. Recommendations for the management of the haematological and onco-haematological aspects of Gaucher disease

    NARCIS (Netherlands)

    Hughes, Derralynn; Cappellini, Maria Domenica; Berger, Marc; van Droogenbroeck, Jan; de Fost, Maaike; Janic, Dragana; Marinakis, Theodore; Rosenbaum, Hanna; Villarubia, Jesús; Zhukovskaya, Elena; Hollak, Carla

    2007-01-01

    Current knowledge of the haematological and onco-haematological complications of type 1 Gaucher disease has been reviewed with the aim of identifying best clinical practice for treatment and disease management. It was concluded that: (i) Awareness of typical patterns of cytopenia can help clinicians

  3. Performance Evaluation and Parameter Identification on DROID III

    Science.gov (United States)

    Plumb, Julianna J.

    2011-01-01

    The DROID III project consisted of two main parts. The former, performance evaluation, focused on the performance characteristics of the aircraft such as lift to drag ratio, thrust required for level flight, and rate of climb. The latter, parameter identification, focused on finding the aerodynamic coefficients for the aircraft using a system that creates a mathematical model to match the flight data of doublet maneuvers and the aircraft s response. Both portions of the project called for flight testing and that data is now available on account of this project. The conclusion of the project is that the performance evaluation data is well-within desired standards but could be improved with a thrust model, and that parameter identification is still in need of more data processing but seems to produce reasonable results thus far.

  4. Lymph nodes cytology in HIV seropositive cases with haematological alterations

    Directory of Open Access Journals (Sweden)

    Neelima Tirumalasetti

    2014-01-01

    Full Text Available Background & objectives: Lymphadenopathy and haematological alterations are the earliest manifestations with other associated opportunistic infections and malignancies. Hence, there is a need for simple investigations like fine needle aspiration cytology (FNAC for evaluation of HIV lymphadenopathy and a haemogram to interpret the haematological alterations. This study was undertaken to analyze the cytological patterns of lymph node lesions in HIV/AIDS patients, to compare with available clinico-pathological and haematological parameters to segregate lymphadenopathy cases for further evaluation. Methods: In the present study, 129 HIV seropositive patients were included. Lymph node aspirates were stained routinely with hematoxylin and eosin and Ziehl-Neelsen (Z-N stains. Special stains and cultures were done in selected patients. Peripheral smears were taken from all the patients and CD4 counts were recorded. Tuberculous lymphadenitis was further categorized. Acid fast bacilli (AFB grading was done on Z-N positive smears. Each lesion was compared with CD4 counts, WHO clinical staging and haematological picture. Results: Cytological diagnosis in 129 patients included tuberculous (n=54, 41.9%, reactive lymphadenopathy (n=46, 35.6%, suppurative (n=16, 12.4% lymphadenitis, non-Hodgkin′s lymphoma (n=4, 3.1%, and Hodgkin′s lymphoma, secondary deposits, other granulomatous lesions, and cryptoccocal lymphadenitis in one patient each. The predominant cytomorphological pattern in tuberculous lymphadenitis was caseous necrosis + epithelioid granuloma formation (51.85%. Grade 2+ Z-N grading was noted in 62.96 per cent of AFB positive smears. CD4 counts showed a descending pattern with progression of WHO clinical staging. Cytopenia was more common in WHO clinical stage IV disease. Interpretation & conclusions: Lymph node cytology was found to be a useful tool for segregating lymphadenopathy cases for further evaluation and for identification of

  5. Blind Source Parameters for Performance Evaluation of Despeckling Filters

    Directory of Open Access Journals (Sweden)

    Nagashettappa Biradar

    2016-01-01

    Full Text Available The speckle noise is inherent to transthoracic echocardiographic images. A standard noise-free reference echocardiographic image does not exist. The evaluation of filters based on the traditional parameters such as peak signal-to-noise ratio, mean square error, and structural similarity index may not reflect the true filter performance on echocardiographic images. Therefore, the performance of despeckling can be evaluated using blind assessment metrics like the speckle suppression index, speckle suppression and mean preservation index (SMPI, and beta metric. The need for noise-free reference image is overcome using these three parameters. This paper presents a comprehensive analysis and evaluation of eleven types of despeckling filters for echocardiographic images in terms of blind and traditional performance parameters along with clinical validation. The noise is effectively suppressed using the logarithmic neighborhood shrinkage (NeighShrink embedded with Stein’s unbiased risk estimation (SURE. The SMPI is three times more effective compared to the wavelet based generalized likelihood estimation approach. The quantitative evaluation and clinical validation reveal that the filters such as the nonlocal mean, posterior sampling based Bayesian estimation, hybrid median, and probabilistic patch based filters are acceptable whereas median, anisotropic diffusion, fuzzy, and Ripplet nonlinear approximation filters have limited applications for echocardiographic images.

  6. Blind Source Parameters for Performance Evaluation of Despeckling Filters.

    Science.gov (United States)

    Biradar, Nagashettappa; Dewal, M L; Rohit, ManojKumar; Gowre, Sanjaykumar; Gundge, Yogesh

    2016-01-01

    The speckle noise is inherent to transthoracic echocardiographic images. A standard noise-free reference echocardiographic image does not exist. The evaluation of filters based on the traditional parameters such as peak signal-to-noise ratio, mean square error, and structural similarity index may not reflect the true filter performance on echocardiographic images. Therefore, the performance of despeckling can be evaluated using blind assessment metrics like the speckle suppression index, speckle suppression and mean preservation index (SMPI), and beta metric. The need for noise-free reference image is overcome using these three parameters. This paper presents a comprehensive analysis and evaluation of eleven types of despeckling filters for echocardiographic images in terms of blind and traditional performance parameters along with clinical validation. The noise is effectively suppressed using the logarithmic neighborhood shrinkage (NeighShrink) embedded with Stein's unbiased risk estimation (SURE). The SMPI is three times more effective compared to the wavelet based generalized likelihood estimation approach. The quantitative evaluation and clinical validation reveal that the filters such as the nonlocal mean, posterior sampling based Bayesian estimation, hybrid median, and probabilistic patch based filters are acceptable whereas median, anisotropic diffusion, fuzzy, and Ripplet nonlinear approximation filters have limited applications for echocardiographic images.

  7. 30 Fulton's condition, organ indices and haematological response of ...

    African Journals Online (AJOL)

    `123456789jkl''''#

    Abstract. This study was conducted to assess the Fulton's condition, organ indices and haematological response of catfish hybrid ... Haematological study is of immense importance .... give information on the stock composite, age at maturity ...

  8. The direction of bilateral transfer depends on the performance parameter.

    Science.gov (United States)

    Pan, Zhujun; van Gemmert, Arend W A

    2013-10-01

    To acquire a more comprehensive understanding of the learning benefits associated with bilateral transfer and to gain knowledge of possible mechanisms behind bilateral transfer, we investigated the transfer direction of several parameters which are assumed to represent important features of movement control in a visuo-motor task. During the study, participants learned a multidirectional point-to-point drawing task in which the visual feedback was rotated 45° and the gain was increased. Performance changes of the untrained hand in movement time, trajectory length, normalized jerk, initial direction error, ratio of the primary sub-movement time to the total movement time, and the accuracy of the aiming movement after the primary sub-movement were investigated as indices of learning from bilateral transfer. The results showed that performance parameters related to the initial production of the movement, such as the initial direction, ratio of primary sub-movement to the total movement time, and movement accuracy after the primary sub-movement, only transferred to the non-dominant, while hand performance variables related to the overall outcome, such as movement duration, movement smoothness, and trajectory length, transferred in both directions. The findings of the current study support the basic principle of the "dynamic dominance model" because it is suggested that overall improvements in the non-dominant system are controlled by trajectory parameters in visuo-motor tasks, which resulted in transference of the afore mentioned production parameters to rather occur to the non-dominant hand as opposed to transference to the dominant hand. Published by Elsevier B.V.

  9. Performance parameters of an ejector-absorption heat transformer

    International Nuclear Information System (INIS)

    Soezen, Adnan; Arcaklioglu, Erol; Oezalp, Mehmet; Yuecesu, Serdar

    2005-01-01

    Ejector-absorption heat transformers (EAHTs) are attractive for increasing a solar-pond's temperature and for recovering low-level waste-heat. Thermodynamic analysis of the performance of an EAHT is complicated due to the associated complex differential equations and simulation programs. This paper proposes the use of artificial neural-networks (ANNs) as a new approach to determine the performance parameters, as functions of only the working temperatures of the EAHT, which is used to increase the solar pond's temperature under various working conditions. Thus, this study is helpful in predicting the performance of an EAHT where the temperatures are known. Scaled conjugate gradient (SCG) and Levenberg-Marquardt (LM) learning algorithms and a logistic sigmoid transfer-function were used in the network. The best approach was investigated for performance parameters with developed software using various algorithms. The best statistical coefficients of multiple determinations (R 2 -values) equal 0.99995, 0.99997 and 0.99995 for the coefficient of performance (COP), exergetic coefficient of performance (ECOP) and circulation ratio (F), respectively obtained by the LM algorithm with seven neurons. In the comparison of performances, results obtained via analytic equations and by means of the ANN, the COP, ECOP and F for all working situations differ by less than 1.05%, 0.7% and 3.07%, respectively. These accuracies are acceptable in the design of the EAHT. The ANN approach greatly reduces the time required by design engineers to find the optimum solution. Apart from reducing the time required, it is possible to find solutions that make solar-energy applications more viable and thus more attractive to potential users. Also, this approach has the advantages of high computational speed, low cost for feasibility, rapid turn-around, which is especially important during iterative design phases, and ease of design by operators with little technical experience

  10. Manipulating perceptual parameters in a continuous performance task.

    Science.gov (United States)

    Shalev, Nir; Humphreys, Glyn; Demeyere, Nele

    2018-02-01

    Sustained attention (SA) is among the most studied faculties of human cognition, and thought to be crucial for many aspects of behavior. Measuring SA often relies on performance on a continuous, low-demanding task. Such continuous performance tasks (CPTs) have many variations, and sustained attention is typically estimated based on variability in reaction times. While relying on reaction times may be useful in some cases, it can pose a challenge when working with clinical populations. To increase interpersonal variability in task parameters that do not rely on speed, researchers have increased demands for memory and response inhibition. These approaches, however, may be confounded when used to assess populations that suffer from multiple cognitive deficits. In the current study, we propose a new approach for increasing task variability by increasing the attentional demands. In order to do so, we created a new variation of a CPT - a masked version, where inattention is more likely to cause misidentifying a target. After establishing that masking indeed decreases target detection, we further investigated which task parameter may influence response biases. To do so, we contrasted two versions of the CPT with different target/distractor ratio. We then established how perceptual parameters can be controlled independently in a CPT. Following the experimental manipulations, we tested the MCCPT with aging controls and chronic stroke patients to assure the task can be used with target populations. The results confirm the MCCPT as a task providing high sensitivity without relying on reaction speed, and feasible for patients.

  11. Effects of dietary acidifer-based diet on haematology and serum ...

    African Journals Online (AJOL)

    A trial was conducted to determine the effect of dietary Biotronics SE® supplementation on haematological and serum parameters of broilers. A total of 120 1-day old Marshall broilers were randomly distributed to four dietary treatments using completely randomized design. Chicks in treatment 1 were fed basal diet (control) ...

  12. The Haematological Profile Of The Sprague-Dawley Outbred Albino ...

    African Journals Online (AJOL)

    The results of the study were discussed in relation to climatic and geographical locational factors (especially temperature) as they affect the normal reference haematological values, and the relevance of haematology in model animal experimentation and biomedical research. Keywords: Haematology, Rat, Sprague-Dawley ...

  13. Haematological and biochemical alterations caused by epidural and intramuscular administration of xylazine hydrochloride in dromedary camels (Camelus dromedarius

    Directory of Open Access Journals (Sweden)

    Omid Azari

    2012-09-01

    Full Text Available This study was conducted in 16 healthy immature dromedary camels weighing 120-150 kg to evaluate and compare the effects of epidural and intramuscular injections of xylazine administered at 0.1 mg/kg and 0.2 mg/kg. Haematological parameters included haemoglobin, packed cell volume, total erythrocyte count and total leukocyte count. Biochemical parameters included alkaline phosphates, alanine aminotransferase, aspartate aminotransferase, blood urea nitrogen, creatinine and glucose. Parameters were measured at different intervals before (baseline and after the administration of drugs. Our study showed that the effect of xylazine on haematological and biochemical parameters is dose-dependant and is also related to the route of administration. The low dose of xylazine administered using both intramuscular and epidural methods showed minimal effects, whereas high doses of the drug, especially when injected intramuscularly, caused greater changes in haematological and biochemical parameters.

  14. Analysis of Network Parameters Influencing Performance of Hybrid Multimedia Networks

    Directory of Open Access Journals (Sweden)

    Dominik Kovac

    2013-10-01

    Full Text Available Multimedia networks is an emerging subject that currently attracts the attention of research and industrial communities. This environment provides new entertainment services and business opportunities merged with all well-known network services like VoIP calls or file transfers. Such a heterogeneous system has to be able satisfy all network and end-user requirements which are increasing constantly. Therefore the simulation tools enabling deep analysis in order to find the key performance indicators and factors which influence the overall quality for specific network service the most are highly needed. This paper provides a study on the network parameters like communication technology, routing protocol, QoS mechanism, etc. and their effect on the performance of hybrid multimedia network. The analysis was performed in OPNET Modeler environment and the most interesting results are discussed at the end of this paper

  15. Turboelectric Aircraft Drive Key Performance Parameters and Functional Requirements

    Science.gov (United States)

    Jansen, Ralph H.; Brown, Gerald V.; Felder, James L.; Duffy, Kirsten P.

    2016-01-01

    The purpose of this paper is to propose specific power and efficiency as the key performance parameters for a turboelectric aircraft power system and investigate their impact on the overall aircraft. Key functional requirements are identified that impact the power system design. Breguet range equations for a base aircraft and a turboelectric aircraft are found. The benefits and costs that may result from the turboelectric system are enumerated. A break-even analysis is conducted to find the minimum allowable electric drive specific power and efficiency that can preserve the range, initial weight, operating empty weight, and payload weight of the base aircraft.

  16. A STUDY ON HAEMATOLOGICAL ABNORMALITIES IN DECOMPENSATED CHRONIC LIVER DISEASE

    Directory of Open Access Journals (Sweden)

    Suresh Moothezhathu Kesavadas

    2017-04-01

    Full Text Available BACKGROUND Liver plays an important role in normal erythropoiesis and synthesis of clotting factors. Chronic liver disease (CLD patients are frequently associated with abnormalities in haematological parameters. MATERIALS AND METHODS This was an observational study conducted among diagnosed CLD patients over a period of 1 year from 2013 to 2014. Various haematological abnormalities in 75 CLD patients were studied. Relevant details were obtained in structured format. RESULTS The mean age of the study group 49.2 years. Male-to-female ratio was 5.8:1. Aetiologies of cirrhosis were alcoholism (61.3%, diabetes mellitus (26.7% and dyslipidaemia (13%. 88% patients were anaemic with severe anaemia (Hb <8 gm% observed in 33.3% patients with mean Hb being 8.76 gm%. Mean Hb in alcohol-related CLDs were lower than CLDs due to other aetiologies (8.62 gm% vs. 9.36 gm%. Most common anaemia observed was normocytic normochromic anaemia (40.9%. 26.7% had leucopenia and 88% had thrombocytopenia. Normal ferritin levels were observed in 6.7%, decreased in 16% and increased in the remaining cases of which a level of more than 900 ng/mL was observed in 18.7% cases. Mean CTP (ChildTurcotte-Pugh score of the study group was 11.1. 80% of patients belong to child C. Patients with high ferritin levels had high CTP score (P-0.001. Platelet count decreases as CTP score increases (P-0.000 and as spleen size increases (P-0.001. CONCLUSION Most common haematological abnormalities observed were thrombocytopenia and anaemia. Severe anaemia was seen in males and alcoholics. Thrombocytopenia was more in those with advanced liver disease and large spleen. High serum ferritin level correlate well with advanced liver disease.

  17. Clinical, haematological and biochemical responses of sheep undergoing autologous blood transfusion

    Directory of Open Access Journals (Sweden)

    Sousa Rejane

    2012-05-01

    Full Text Available Abstract Background This study aimed to evaluate the clinical, haematological and biochemical responses to autologous blood transfusion and the feasibility of this practice in sheep. Thus, we used eight male, 8 months old sheep, weighing on average 30 kg, from which 15 mL/kg of whole blood was collected and stored in CPDA-1 bags. Blood samples were refrigerated for 8 days and subsequently re-infused. The clinical, haematological and biochemical parameters were evaluated before blood collection and reinfusion, after 10 minutes of collection and reinfusion, after 3, 6, 12, 24, 48, 96 and 192 hours after collection and reinfusion. Results With respect to clinical parameters, we observed a decrease in heart rate after 24, 48 and 196 hours from reinfusion compared to basal values (p p p p  Conclusion Autologous transfusion in sheep slightly altered the physiological, biochemical and haematological responses of sheep, indicating that the technique proposed is safe and can be applied in the clinical practice of this species. The 8 d period was not sufficient for complete recovery of the haematological parameters after blood collection.

  18. The ETH Zurich AMS facilities: Performance parameters and reference materials

    Energy Technology Data Exchange (ETDEWEB)

    Christl, M., E-mail: mchristl@phys.ethz.ch [Laboratory of Ion Beam Physics, ETH Zurich, 8093 Zurich (Switzerland); Vockenhuber, C.; Kubik, P.W.; Wacker, L.; Lachner, J.; Alfimov, V.; Synal, H.-A. [Laboratory of Ion Beam Physics, ETH Zurich, 8093 Zurich (Switzerland)

    2013-01-15

    The current performance of all three AMS systems in operation at ETH Zurich, the 6 MV HVEC EN-Tandem facility 'TANDEM', the 0.5 MV NEC Pelletron 'TANDY', and the 0.2 MV system 'MICADAS' is summarized. Radionuclides routinely measured with these AMS systems include {sup 10}Be, {sup 14}C, {sup 26}Al, {sup 36}Cl, {sup 41}Ca, {sup 129}I and the actinides. The reference materials used for the normalization of the AMS measurements at the ETH Zurich AMS facilities are presented. This paper therefore is a comprehensive status report of all three AMS systems currently operated by the Laboratory of Ion Beam Physics (LIP) at ETH Zurich and documents their performance and operation parameters.

  19. Decoupling interrelated parameters for designing high performance thermoelectric materials.

    Science.gov (United States)

    Xiao, Chong; Li, Zhou; Li, Kun; Huang, Pengcheng; Xie, Yi

    2014-04-15

    The world's supply of fossil fuels is quickly being exhausted, and the impact of their overuse is contributing to both climate change and global political unrest. In order to help solve these escalating problems, scientists must find a way to either replace combustion engines or reduce their use. Thermoelectric materials have attracted widespread research interest because of their potential applications as clean and renewable energy sources. They are reliable, lightweight, robust, and environmentally friendly and can reversibly convert between heat and electricity. However, after decades of development, the energy conversion efficiency of thermoelectric devices has been hovering around 10%. This is far below the theoretical predictions, mainly due to the interdependence and coupling between electrical and thermal parameters, which are strongly interrelated through the electronic structure of the materials. Therefore, any strategy that balances or decouples these parameters, in addition to optimizing the materials' intrinsic electronic structure, should be critical to the development of thermoelectric technology. In this Account, we discuss our recently developed strategies to decouple thermoelectric parameters for the synergistic optimization of electrical and thermal transport. We first highlight the phase transition, which is accompanied by an abrupt change of electrical transport, such as with a metal-insulator and semiconductor-superionic conductor transition. This should be a universal and effective strategy to optimize the thermoelectric performance, which takes advantage of modulated electronic structure and critical scattering across phase transitions to decouple the power factor and thermal conductivity. We propose that solid-solution homojunction nanoplates with disordered lattices are promising thermoelectric materials to meet the "phonon glass electron crystal" approach. The formation of a solid solution, coupled with homojunctions, allows for

  20. Key parameters controlling the performance of catalytic motors

    Energy Technology Data Exchange (ETDEWEB)

    Esplandiu, Maria J.; Afshar Farniya, Ali [Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and The Barcelona Institute of Science and Technology, Campus UAB, Bellaterra, 08193 Barcelona (Spain); Reguera, David, E-mail: dreguera@ub.edu [Departament de Física Fonamental, Universitat de Barcelona, C/Martí i Franquès 1, 08028 Barcelona (Spain)

    2016-03-28

    The development of autonomous micro/nanomotors driven by self-generated chemical gradients is a topic of high interest given their potential impact in medicine and environmental remediation. Although impressive functionalities of these devices have been demonstrated, a detailed understanding of the propulsion mechanism is still lacking. In this work, we perform a comprehensive numerical analysis of the key parameters governing the actuation of bimetallic catalytic micropumps. We show that the fluid motion is driven by self-generated electro-osmosis where the electric field originates by a proton current rather than by a lateral charge asymmetry inside the double layer. Hence, the surface potential and the electric field are the key parameters for setting the pumping strength and directionality. The proton flux that generates the electric field stems from the proton gradient induced by the electrochemical reactions taken place at the pump. Surprisingly the electric field and consequently the fluid flow are mainly controlled by the ionic strength and not by the conductivity of the solution, as one could have expected. We have also analyzed the influence of the chemical fuel concentration, electrochemical reaction rates, and size of the metallic structures for an optimized pump performance. Our findings cast light on the complex chemomechanical actuation of catalytic motors and provide important clues for the search, design, and optimization of novel catalytic actuators.

  1. Haematological and biochemical responses of starter broiler ...

    African Journals Online (AJOL)

    A study was conducted to investigate the haematological and biochemical responses of starter broiler chickens fed copper and probiotics supplemented diets. A total of 180-day old Marshal broiler chicks were randomly allotted to six treatment groups of 30 birds each. The treatments were divided into three replicates of ten ...

  2. Haematological characteristics of the African snakehead ...

    African Journals Online (AJOL)

    The haematological characteristics of the African snakehead Parachanna obscura includes mean blood haemoglobin concentration of 5.70g/dl, mean haematocrit of 19.20%, mean red blood cell count of 1.67 x 10 12/L, mean total white blood cell count of 19.07 x 103 mm-3, mean erythrocytic haemoglobin concentration of ...

  3. Haematological And Biochemical Effects Of Sulphadimidine In ...

    African Journals Online (AJOL)

    Haematological and biochemical efects of sulphadmidine were studied in Nigerian mongrel dogs. Five Nigerian mongrel dogs of either sex weighing between 7 and 12 kg were used for the study. The pretreatment blood and serum samples were collected and the weight of animals taken before the administraton of 100 ...

  4. Haematological changes in HIV infection with correlation to CD4 cell count

    Directory of Open Access Journals (Sweden)

    SS Parinitha

    2012-03-01

    Full Text Available BackgroundHIV infection is associated with a wide range of haematological abnormalities.Methods and ObjectivesThe objectives in this study were to study haematological changes in HIV patients and to correlate them with CD4 cell counts. Two hundred and fifty HIV positive patients referred to the haematology laboratory section for complete haemogram in whom CD4 count was done were included in the study. Haematologic parameters and CD4 counts were studied in each of these patients.Descriptive statistics were applied. Association between two attributes was calculated by chi-square test and p value less than 0.05 was considered statistically significant.ResultsAmong 250 patients, anaemia was seen in 210 (84% cases. The most common type was normocytic normochromic (40.4%. Lymphopenia was seen in 163 (65.2% cases and thrombocytopenia in 45 (18% cases. The majority of cases (70% had CD4 cell counts below 200 cells/mm3. Fifty-four cases (21.6% had CD4 counts between 200 to 499 cells/mm3 and 21 (8.4% cases had CD4 counts more than 500 cells/ mm3.In patients with CD4 counts less than 200 cells/mm3, anaemia was seen in 91.4% cases, leucopenia in 26.8%cases, lymphopenia in 80% cases and thrombocytopenia in 21.7% cases.ConclusionHaematologic manifestations of HIV infection are common and more frequent with progression of disease. The present study revealed a significant increase in the number of cases of anaemia, and lymphopenia, with decreasing CD4 cell counts. Thrombocytopenia is also seen but does not show significant increase with disease progression. The study also highlights the importance of simultaneously treating HIV patients for haematologic manifestations to reduce morbidity.

  5. Safety parameter display systems' effect on operator performance

    International Nuclear Information System (INIS)

    Cerven, F.; Ford, R.E.; Blackman, H.S.

    1983-01-01

    Computer generated displays are a powerful and flexible tool for presenting data to the operators of nuclear power plants. Such displays are currently being developed in industry for use as safety parameter displays and for use in advanced control rooms. There exists a need for methods to objectively evaluate the effect of these displays, positive or negative, on the performance of control room personnel. Results of developing one such method, noninteractive simulation, and the two experiments that were performed to determine if it can be used as a method for evaluating computer displays are presented. This method is more objective and powerful than pencil and paper methods because it measures human performance rather than opinion or perference, has excellent control of the experimental variables, and has a higher fidelity to the control room environment. The results of these experiments indicates that the present methodology does not differentiate among the display types tested at a statistically significant level. In other words, all display types tested worked equally well in providing operators needed information

  6. Haematological status of wintering great tits (Parus major) along a metal pollution gradient

    Energy Technology Data Exchange (ETDEWEB)

    Geens, Ann, E-mail: ann.geens@ua.ac.be [Department of Biology, University of Antwerp, Ethology, Universiteitsplein 1, B-2610 Antwerp (Belgium); Dauwe, Tom [Department of Biology, University of Antwerp, Ethology, Universiteitsplein 1, B-2610 Antwerp (Belgium); VITO, Boeretang 200, B-2400 Mol (Belgium); Bervoets, Lieven; Blust, Ronny [Department of Biology, University of Antwerp, Ecophysiology, Biochemistry and Toxicology, Groenenborgerlaan 171, B-2020 Antwerp (Belgium); Eens, Marcel [Department of Biology, University of Antwerp, Ethology, Universiteitsplein 1, B-2610 Antwerp (Belgium)

    2010-02-01

    In the long-term biomonitoring of wild populations inhabiting polluted areas, the use of non-destructive biomarkers as markers of condition is very important. We examined the possible effects of metal pollution on the haematological status of adult great tits (Parus major) along a well-established pollution gradient near a non-ferrous smelter in Belgium. We measured blood and feather metal concentrations and assessed the haematological status (amount of red blood cells, haemoglobin concentration, haematocrit, mean corpuscular volume and mean corpuscular haemoglobin) of adult great tits during winter at four study sites. Metal concentrations in blood and feathers indicated that cadmium and lead were the most important metals in the pollution gradient under study. Measurements of haematological parameters revealed that haemoglobin concentration, haematocrit, mean corpuscular volume and mean corpuscular haemoglobin were lower in great tits from the more polluted sites. These parameters were significantly negatively correlated with blood lead concentration. The amount of red blood cells, however, did not significantly differ among study sites. Our results indicate that the haematological status of great tits is negatively affected by metal pollution and may therefore be used as a successful biomarker for monitoring the negative impact of metal exposure in the wild.

  7. Intestinal helminths induce haematological changes in dogs from Jabalpur, India.

    Science.gov (United States)

    Qadir, S; Dixit, A K; Dixit, P; Sharma, R L

    2011-12-01

    The effect of canine intestinal helminths on the haematological profile of 200 dogs, of both sexes and variable age, visiting university veterinary clinics for routine examination was investigated. The dogs were assigned to parasitized (n = 39) and non-parasitized (n = 161) groups of animals. Coprological examination revealed a 19.5% prevalence of different species of the helminths. Of these animals, 10.25% had mixed infections with Ancylostoma caninum, Toxascaris spp. and Dipylidium caninum. The intensity of A. caninum infection was the highest, with mean egg counts of 951.43 (standard error 88.66), followed by Toxascaris 283.33 (standard error 116.81) and D. caninum. The parasitized animals had significantly lower levels of haemoglobin, packed cell volume and total erythrocyte counts than non-parasitized animals (P < 0.01). Values of other parameters, except for lymphocytes and eosinophils, were not different between the two groups. Analyses of the haematological profile revealed normocytic hypochromic anaemia in the parasitized group of animals.

  8. A Profile of Fitness Parameters and Performance of Volleyball Players

    Directory of Open Access Journals (Sweden)

    Govind B. Taware

    2013-07-01

    Full Text Available Background: Ball games require comprehen-sive ability including physical, technical, men-tal and tactical abilities. Among them, physicalabilities of players exert marked effects on theskill of the players themselves and the tacticsof the team. Therefore players must have thephysical abilities to meet the demand of thesport. Volleyball is one of the most popularlyplayed games in the world. Unfortunately, thelevel of performance of the Indian volleyballplayers lags far behind the international stan-dards. Aim of the Study: The present study wasaimed to assess flexibility, muscular endurance,power and cardio-respiratory endurance of vol-leyball players and to compare the results withage matched controls. Also, to compare thefindings of the volleyball players with that ofthe international norms from the available lit-erature and to make some suggestions for theimprovement in their performance level. Ma-terial and Methods: The study was carried outin 40 male volleyball players aged between 17to 26 years and 40 ages matched male controls.Physical fitness parameters namely flexibility,muscular endurance, power and cardio-respi-ratory endurance were measured, data was ana-lyzed using unpaired ‘t’-test. Results: It was ob-served that all physical fitness parameters weresignificantly more in players as compared totheir aged-matched controls but when values ofthe subjects were compared to internationalstandards; our subjects were behind the recom-mended norms for the elite volleyball players.Conclusion: The volleyball players have moreadvantage of flexibility muscular endurance,power and cardio-respiratory endurance.

  9. Performance Parameters and Characterizations of Nanocrystals: A Brief Review

    Directory of Open Access Journals (Sweden)

    Manasi M. Chogale

    2016-08-01

    Full Text Available Poor bioavailability of drugs associated with their poor solubility limits the clinical effectiveness of almost 40% of the newly discovered drug moieties. Low solubility, coupled with a high log p value, high melting point and high dose necessitates exploration of alternative formulation strategies for such drugs. One such novel approach is formulation of the drugs as “Nanocrystals”. Nanocrystals are primarily comprised of drug and surfactants/stabilizers and are manufactured by “top-down” or “bottom-up” methods. Nanocrystals aid the clinical efficacy of drugs by various means such as enhancement of bioavailability, lowering of dose requirement, and facilitating sustained release of the drug. This effect is dependent on the various characteristics of nanocrystals (particle size, saturation solubility, dissolution velocity, which have an impact on the improved performance of the nanocrystals. Various sophisticated techniques have been developed to evaluate these characteristics. This article describes in detail the various characterization techniques along with a brief review of the significance of the various parameters on the performance of nanocrystals.

  10. Current problems in haematology. 2: Hereditary spherocytosis.

    OpenAIRE

    Smedley, J C; Bellingham, A J

    1991-01-01

    Hereditary spherocytosis is a relatively common haematological disorder and will be encountered by all haematologists. The abundance of new information, dealing principally with molecular and genetic aspects of pathophysiology, is beginning to have implications for its investigation and management. While these advances have not yet exerted a large influence at therapeutic level, the promise of such advents as prenatal diagnosis make this an exciting field to watch.

  11. Assigning probability distributions to input parameters of performance assessment models

    Energy Technology Data Exchange (ETDEWEB)

    Mishra, Srikanta [INTERA Inc., Austin, TX (United States)

    2002-02-01

    This study presents an overview of various approaches for assigning probability distributions to input parameters and/or future states of performance assessment models. Specifically,three broad approaches are discussed for developing input distributions: (a) fitting continuous distributions to data, (b) subjective assessment of probabilities, and (c) Bayesian updating of prior knowledge based on new information. The report begins with a summary of the nature of data and distributions, followed by a discussion of several common theoretical parametric models for characterizing distributions. Next, various techniques are presented for fitting continuous distributions to data. These include probability plotting, method of moments, maximum likelihood estimation and nonlinear least squares analysis. The techniques are demonstrated using data from a recent performance assessment study for the Yucca Mountain project. Goodness of fit techniques are also discussed, followed by an overview of how distribution fitting is accomplished in commercial software packages. The issue of subjective assessment of probabilities is dealt with in terms of the maximum entropy distribution selection approach, as well as some common rules for codifying informal expert judgment. Formal expert elicitation protocols are discussed next, and are based primarily on the guidance provided by the US NRC. The Bayesian framework for updating prior distributions (beliefs) when new information becomes available is discussed. A simple numerical approach is presented for facilitating practical applications of the Bayes theorem. Finally, a systematic framework for assigning distributions is presented: (a) for the situation where enough data are available to define an empirical CDF or fit a parametric model to the data, and (b) to deal with the situation where only a limited amount of information is available.

  12. Assigning probability distributions to input parameters of performance assessment models

    International Nuclear Information System (INIS)

    Mishra, Srikanta

    2002-02-01

    This study presents an overview of various approaches for assigning probability distributions to input parameters and/or future states of performance assessment models. Specifically,three broad approaches are discussed for developing input distributions: (a) fitting continuous distributions to data, (b) subjective assessment of probabilities, and (c) Bayesian updating of prior knowledge based on new information. The report begins with a summary of the nature of data and distributions, followed by a discussion of several common theoretical parametric models for characterizing distributions. Next, various techniques are presented for fitting continuous distributions to data. These include probability plotting, method of moments, maximum likelihood estimation and nonlinear least squares analysis. The techniques are demonstrated using data from a recent performance assessment study for the Yucca Mountain project. Goodness of fit techniques are also discussed, followed by an overview of how distribution fitting is accomplished in commercial software packages. The issue of subjective assessment of probabilities is dealt with in terms of the maximum entropy distribution selection approach, as well as some common rules for codifying informal expert judgment. Formal expert elicitation protocols are discussed next, and are based primarily on the guidance provided by the US NRC. The Bayesian framework for updating prior distributions (beliefs) when new information becomes available is discussed. A simple numerical approach is presented for facilitating practical applications of the Bayes theorem. Finally, a systematic framework for assigning distributions is presented: (a) for the situation where enough data are available to define an empirical CDF or fit a parametric model to the data, and (b) to deal with the situation where only a limited amount of information is available

  13. Optimization of Performance Parameters for Large Area Silicon Photomultipliers

    Science.gov (United States)

    Janzen, Kathryn

    2008-10-01

    The goal of the GlueX experiment is to search for exotic hybrid mesons as evidence of gluonic excitations in an effort to better understand confinement. A key component of the GlueX detector is the electromagnetic barrel calorimeter (BCAL) located immediately inside a superconducting solenoid of approximately 2.5T. Because of this arrangement, traditional vacuum photomultiplier tubes (PMTs) which are affected significantly by magnetic fields cannot be used on the BCAL. The use of Silicon photomultipliers (SiPMs) as front-end detectors has been proposed. While the largest SiPMs that have been previously employed by other experiments are 1x1 mm^2, GlueX proposes to use large area SiPMs each composed of 16 - 3x3 mm^2 cells in a 4x4 array. This puts the GlueX collaboration in the unique position of driving the technology for larger area sensors. In this talk I will discuss tests done in Regina regarding performance parameters of prototype SiPM arrays delivered by SensL, a photonics research and development company based in Ireland, as well as sample 1x1 mm^2 and 3x3 mm^2 SiPMs.

  14. Performance Analysis of Different NeQuick Ionospheric Model Parameters

    Directory of Open Access Journals (Sweden)

    WANG Ningbo

    2017-04-01

    Full Text Available Galileo adopts NeQuick model for single-frequency ionospheric delay corrections. For the standard operation of Galileo, NeQuick model is driven by the effective ionization level parameter Az instead of the solar activity level index, and the three broadcast ionospheric coefficients are determined by a second-polynomial through fitting the Az values estimated from globally distributed Galileo Sensor Stations (GSS. In this study, the processing strategies for the estimation of NeQuick ionospheric coefficients are discussed and the characteristics of the NeQuick coefficients are also analyzed. The accuracy of Global Position System (GPS broadcast Klobuchar, original NeQuick2 and fitted NeQuickC as well as Galileo broadcast NeQuickG models is evaluated over the continental and oceanic regions, respectively, in comparison with the ionospheric total electron content (TEC provided by global ionospheric maps (GIM, GPS test stations and JASON-2 altimeter. The results show that NeQuickG can mitigate ionospheric delay by 54.2%~65.8% on a global scale, and NeQuickC can correct for 71.1%~74.2% of the ionospheric delay. NeQuick2 performs at the same level with NeQuickG, which is a bit better than that of GPS broadcast Klobuchar model.

  15. Haematological reference values for full-term, healthy, newborns of Karachi, Pakistan.

    Science.gov (United States)

    Qaiser, Danish Hasan; Sandila, Mohammad Perwaiz; Ahmed, Syed Tousif; Kazmi, Tahseen

    2009-09-01

    To establish reference haematological values (complete blood count) in healthy full-term newborns of Karachi. This is a cross sectional study design based on cord blood sample of 404 newborns and their mothers recruited from Sindh Government Qatar Hospital, Ziauddin University Hospital gole market campus, Sindh Government hospital, Liaquatabad and Chinniot maternity and child hospital. Karachi from July 2006 to April 2008. Both mother's and the new born baby's blood was collected in EDTA containing tubes and analyzed for different haematological parameters. The data entry and analysis was done on computer package SPSS (Statistical Packages of Social Sciences) version 12.0. The results were given in the text as mean, standard deviation and 95% confidence intervals of haematological values (complete blood count). The mean haemoglobin was found to be (14.99 +/- 1.47 gm), which is lower than the standard value described in literature. However the total WBCs count and platelet count were found to be (13.61 +/- 4.23) and (256. 25 +/- 76.54) respectively, which were similar to the other studies. Our values provide reference range for haematological values in healthy newborns of Karachi, for clinical use by our physicians.

  16. Thermal-hydraulic Parameters of WWER-440 Fuel Performance

    International Nuclear Information System (INIS)

    Kacmar, M.

    1999-01-01

    In this lecture the thermodynamic characteristics of reactor core V230, V213 (design concept and the distribution of coolant flow inside the reactor vessel and basic T-H parameters), allowed reactor regimes and reactor core flow factor as well as thermodynamic parameters and impact to fuel leakage are presented

  17. Effects of Exercise Training on Haematology and Maximal Cardiac Output

    DEFF Research Database (Denmark)

    Bonne, Thomas Christian

    = 0.051) and time to complete 3000 m tended (P = 0.09) to increase in LHTH but not after sea level training. In study III haematological parameters were determined weekly three times before and four times after classical altitude and sea level training and ABP thresholds for [Hb], %ret, OFF......-score and the abnormal blood profile score (ABPS) were generated using the official ABP software. After altitude training, six swimmers exceeded the 99% ABP thresholds: Two swimmers exceeded the OFF-score thresholds at day 7; One swimmer exceeded the OFF-score threshold at day 28; One swimmer exceeded the threshold...... for %ret at day 14; One swimmer surpassed the ABPS threshold at day 7 and one swimmer exceeded the ABPS threshold 28 days after altitude training. No values exceeded the individual thresholds in the control group. In conclusion, this thesis demonstrated that BV is a main determinant of the exercise induced...

  18. Growth Performance and Hematological Traits of Weaner Pigs Fed ...

    African Journals Online (AJOL)

    BSN

    http://www.ajol.info/index.php/njb/index and ... for their growth and haematological parameters when fed graded levels of raw ... significant (P<0.05) differences among treatments in feed intake, weight gain, ... Keywords: Growth Performance, Bambara nut wastes, Weaner Pigs and ... waste used in the feeding of pigs (Okeke,.

  19. Performance of broiler chickens fed neem ( Azadirachta indica ) leaf ...

    African Journals Online (AJOL)

    One hundred and ninety-two day-old marshal broilers were used in an eight weeks feeding trial to evaluate the effects of neem (Azadirachta indica) leaf meal on growth performance and haematological parameters of broiler chickens. The birds were randomly assigned into four (4) groups of forty eight (48) birds each in a ...

  20. Altitude training causes haematological fluctuations with relevance for the Athlete Biological Passport

    DEFF Research Database (Denmark)

    Bonne, Thomas Christian; Lundby, Carsten; Lundby, Anne Kristine

    2015-01-01

    The impact of altitude training on haematological parameters and the Athlete Biological Passport (ABP) was evaluated in international-level elite athletes. One group of swimmers lived high and trained high (LHTH, n = 10) for three to four weeks at 2130 m or higher whereas a control group (n = 10......) completed a three-week training camp at sea-level. Haematological parameters were determined weekly three times before and four times after the training camps. ABP thresholds for haemoglobin concentration ([Hb]), reticulocyte percentage (RET%), OFF score and the abnormal blood profile score (ABPS) were...... calculated using the Bayesian model. After altitude training, six swimmers exceeded the 99% ABP thresholds: two swimmers exceeded the OFF score thresholds at day +7; one swimmer exceeded the OFF score threshold at day +28; one swimmer exceeded the threshold for RET% at day +14; and one swimmer surpassed...

  1. Pre-operative haematological investigations in paediatric orofacial ...

    African Journals Online (AJOL)

    Pre-operative haematological investigations in paediatric orofacial cleft repair: Any relevance to management outcome? ... Aim and Objectives: To determine the value of routine pre-operative haematologic investigations in children undergoing orofacial cleft repair. Background: Although routine pre-operative laboratory ...

  2. haematology of the west african dwarf sheep under two different

    African Journals Online (AJOL)

    Dr Olaleye

    The coat is usually white in colour or a mixture of black and white. They weight about 30kg. Although there are a number of studies on the normal haematology of the West Africa Dwarf Sheep (Oduye, 1976, Durotoye 1987, Oyewale, 1991), there is no report on the influence of management on the haematology of these ...

  3. Audit of clinical-laboratory practices in haematology and blood ...

    African Journals Online (AJOL)

    In Tanzania, there is paucity of data for monitoring laboratory medicine including haematology. This therefore calls for audits of practices in haematology and blood transfusion in order to provide appraise practice and devise strategies that would result in improved quality of health care services. This descriptive ...

  4. Hospital end-of-life care in haematological malignancies.

    Science.gov (United States)

    Beaussant, Yvan; Daguindau, Etienne; Chauchet, Adrien; Rochigneux, Philippe; Tournigand, Christophe; Aubry, Régis; Morin, Lucas

    2018-02-06

    To investigate patterns of care during the last months of life of hospitalised patients who died from different haematological malignancies. Nationwide register-based study, including all hospitalised adults ≥20 years who died from haematological malignancies in France in 2010-2013. Outcomes included use of invasive cancer treatments and referral to palliative care. Percentages are adjusted for sex and age using direct standardisation. Of 46 629 inpatients who died with haematological malignancies, 24.5% received chemotherapy during the last month before death, 48.5% received blood transfusion, 12.3% were under invasive ventilation and 18.1% died in intensive care units. We found important variations between haematological malignancies. The use of chemotherapy during the last month of life varied from 8.6% among patients with chronic myeloid leukaemia up to 30.1% among those with non-Hodgkin's lymphoma (Pcare units. A high proportion of patients who died from haematological malignancies receive specific treatments near the end of life. There is a need for a better and earlier integration of the palliative care approach in the standard practice of haematology. However, substantial variation according to the type of haematological malignancy suggests that the patients should not be considered as one homogeneous group. Implementation of palliative care should account for differences across haematological malignancies. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  5. Haematological and serum enzymes biomarkers of heavy metals in ...

    African Journals Online (AJOL)

    Haematological and serum enzymes biomarkers of heavy metals in Chrysichthys Nigrodigitatus and Cynoglossus senegalensis. ... Haematological and serum enzymes activities are predilective biomarkers for the detection and monitoring of aquatic ecosystems pollution. The inclusion of Allium sativum at 1.5g/kg is ...

  6. Parasitaemia and haematological changes in malaria-infected ...

    African Journals Online (AJOL)

    reported that this disease affects more than a million cross-border migrants, including ... mosquito. Some refugees from non-malaria areas, or areas where the prevalence of ... underlying factors that cause haematological alterations, may be present. This research ... Haematology Analyser (Sysmex, Canada). The analyser ...

  7. Perceived need for information among patients with a haematological malignancy: associations with information satisfaction and treatment decision-making preferences.

    NARCIS (Netherlands)

    Rood, J.A.; van Zuuren, F.J.; Stam, F.; van der Ploeg, T.; Eeltink, C.M.; de Leeuw, I.M.; Huijgens, P.C.

    2015-01-01

    For patients with haematological malignancies, information on disease, prognosis, treatment and impact on quality of life is of the utmost importance. To gain insight into the perceived need for information in relation to sociodemographic and clinical parameters, comorbidity, quality of life (QoL)

  8. Perceived need for information among patients with a haematological malignancy: associations with information satisfaction and treatment decision-making preferences

    NARCIS (Netherlands)

    Rood, J.A.J.; van Zuuren, F.J.; Stam, F.; van der Ploeg, T.; Eeltink, C.; Verdonck-de Leeuw, I.M.; Huijgens, P.C.

    2015-01-01

    For patients with haematological malignancies, information on disease, prognosis, treatment and impact on quality of life is of the utmost importance. To gain insight into the perceived need for information in relation to sociodemographic and clinical parameters, comorbidity, quality of life (QoL)

  9. Effect of chronic garlic feeding on some haematological parameters ...

    African Journals Online (AJOL)

    200mg/kg) daily for thirty days. Garlic feeding for 30 days significantly (P<0.05) increased the red cell count, haemoglobin concentration and the PCV when compared with the control. Also garlic fed rat showed a significant increase in total white ...

  10. the effect of potassium bromate on some haematological parameters ...

    African Journals Online (AJOL)

    Daniel Owu

    Nigeria, 1 Department of Medical Biochemistry, College of Medicine,. University of Nigeria ... water pH, it should exist almost exclusively in the ionic form ... containers. We measured .... WHO (1993). Guidelines for Drinking Water Quality, 2nd.

  11. Some Haematological And Serum Biochemical Parameters Of Goats ...

    African Journals Online (AJOL)

    RBC) and haemoglobin when blood samples were collected on Day 63. Diet C had significantly P<0.05 higher values for TP (7.6g ... Spondias mombin, Gmelina arbore. Journal of Agriculture, Forestry and the Social Sciences Vol. 4 (2) 2006: pp.

  12. Effect Of Supplementation On Haematological And Biochemical Parameters During Pregnancy

    Directory of Open Access Journals (Sweden)

    Mohapatra P

    1988-01-01

    Full Text Available One hundred forty eight antenatal women were studied as supplemented (70 and non-supplemented (78 groups. The former group received nutritional supplementation in addition, to Iron, Folic acid and calcium tablets, which were given to both the groups. There was significant increase in the serum protein (p<0.001 and albumin (p<0.001 levels of the supplemented women. Haemoglobin was found to be increased in both the groups because of Iron therapy. But the increment was significantly higher (p<0.001 in supplemented group. Thus apart from Iron and Folic Acid, a diet rich in proteins (11 gm with calories (330 kcal is essential during pregnancy, at least for a period of 100 days.

  13. Changes of Haematological Parameters in Common Pheasant Throughout the Year

    Czech Academy of Sciences Publication Activity Database

    Hauptmanová, K.; Malý, Marek; Literák, I.

    2006-01-01

    Roč. 51, č. 1 (2006), s. 29-34 ISSN 0375-8427 Source of funding: V - iné verejné zdroje Keywords : Phasianus colchicus * erythrocytes * leucocytes Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 0.624, year: 2006

  14. Haematological factors in the management of adult epistaxis: systematic review.

    Science.gov (United States)

    Williams, A; Biffen, A; Pilkington, N; Arrick, L; Williams, R J; Smith, M E; Smith, M; Birchall, J

    2017-12-01

    The management of epistaxis requires an understanding of haematological factors that may complicate its treatment. This systematic review includes six distinct reviews examining the evidence supporting epistaxis-specific management strategies relating to warfarin, direct oral anticoagulants, heparin, antiplatelet agents, tranexamic acid and transfusion. A systematic review of the literature was performed using a standardised methodology and search strategy. Limited numbers of articles were identified in each systematic review, with level 1 evidence only regarding the use of tranexamic acid. No studies met the inclusion criteria within the heparin, direct oral anticoagulants or transfusion systematic reviews. Many studies were limited by small sample sizes and significant risk of bias. The management of major bleeding and transfusion practice is well documented in national guidance from multiple sources. The guidelines include advice on anticoagulants, antiplatelet agents and tranexamic acid. In the absence of more specific evidence, these guidelines should be applied in the management of epistaxis.

  15. Assessment of non-genetic parameters of the racing performances ...

    African Journals Online (AJOL)

    From 1995 to 2007, flat racing data was collected for Thoroughbred and Arabian horses in Algeria. Non-genetic factors affecting racing performances have been identified and quantified using linear models. Performances are represented through the earnings and the rankings. Three traits were used: two earnings traits [the ...

  16. Evaluation of the main parameters affecting seismic performance of ...

    Indian Academy of Sciences (India)

    The current study considers forty eight (48) 3-D RC building models to .... Acceptance criteria for members and performance level criteria for buildings are ..... Evaluation and Retrofit of Concrete Buildings, Applied Technology Council, Vol 1.

  17. Evaluation of bio-accumulation stress in chicken by arsenite: haematological case study

    International Nuclear Information System (INIS)

    Rasul, L.; Tufail, S.; Rasool, H.

    2016-01-01

    Water. This bio-accumulation disturbs the eco-physiological and blood parameters. Haematological studies of anti-coagulated and serum blood samples core parameters reveals that As (III) contamination in drinking water is the significant source of adverse disturbance of blood parameters of red blood cell, white blood cell, hemoglobin, packed cell volume, sodium, calcium, potassium ions, albumin, urea, creatinine and cholesterol, with a highly significant p value of less than 0.01 after 14th brooding day with bio-accumulation of 25.8 micro g/L of As (III) in blood samples. (author)

  18. Normal haematology and blood biochemistry of wild Nile crocodiles (Crocodylus niloticus in the Okavango Delta, Botswana

    Directory of Open Access Journals (Sweden)

    C.J. Lovely

    2007-06-01

    Full Text Available Wild Nile crocodiles (Crocodylus niloticus of various size classes were captured in the Okavango Delta, Botswana. Blood was collected from the post occipital sinus and used for the determination of a wide range of haematological and biochemical parameters. These values were compared between the sexes and between 3 size classes. The values were also compared with the limited data available from farmed Nile crocodiles, as well as from other wild Nile crocodiles. The Okavango crocodiles were comparatively anaemic, and had comparatively low total protein and blood glucose levels. There was a high prevalence of Hepatozoon pettiti infection, however, there was no significant difference in haematological values between the infected and uninfected crocodiles. The values reported here will be useful in diagnostic investigations in both zoo and farmed Nile crocodiles.

  19. Altitude training causes haematological fluctuations with relevance for the Athlete Biological Passport.

    Science.gov (United States)

    Bonne, Thomas Christian; Lundby, Carsten; Lundby, Anne Kristine; Sander, Mikael; Bejder, Jacob; Nordsborg, Nikolai Baastrup

    2015-08-01

    The impact of altitude training on haematological parameters and the Athlete Biological Passport (ABP) was evaluated in international-level elite athletes. One group of swimmers lived high and trained high (LHTH, n = 10) for three to four weeks at 2130 m or higher whereas a control group (n = 10) completed a three-week training camp at sea-level. Haematological parameters were determined weekly three times before and four times after the training camps. ABP thresholds for haemoglobin concentration ([Hb]), reticulocyte percentage (RET%), OFF score and the abnormal blood profile score (ABPS) were calculated using the Bayesian model. After altitude training, six swimmers exceeded the 99% ABP thresholds: two swimmers exceeded the OFF score thresholds at day +7; one swimmer exceeded the OFF score threshold at day +28; one swimmer exceeded the threshold for RET% at day +14; and one swimmer surpassed the ABPS threshold at day +14. In the control group, no values exceeded the individual ABP reference range. In conclusion, LHTH induces haematological changes in Olympic-level elite athletes which can exceed the individually generated references in the ABP. Training at altitude should be considered a confounding factor for ABP interpretation for up to four weeks after altitude exposure but does not consistently cause abnormal values in the ABP. Copyright © 2014 John Wiley & Sons, Ltd.

  20. HAEMATOLOGICAL IMPACT OF NATURALLY OCCURING TICK BORNE HAEMOPARASITIC INFECTIONS IN CATTLE OF WEST BENGAL, INDIA

    Directory of Open Access Journals (Sweden)

    Apurba Debbarma

    2017-12-01

    Full Text Available Haemoparasites reduces productivity and may lead to high mortality among animals. The present study was carried out to evaluate the heamotological change in cattle of different districts in West Bengal, India affected with naturally occurring tick- borne haemoparasitic diseases (TBHD. A total of 310 cattle blood samples were screened for the presence of haemoparasites from July, 2015 to June, 2016. The blood samples were examined for haemoparasites by making thin blood smear and staining with Giemsa’s stain. The result showed that108 (34.84% cattle were found positive with TBHD, out of which 22.9% were Theileria sp, 5.8% were Babesia sp., 11.93% Anaplasma sp., and 5.8% were having mixed infection, respectively. The positive samples were subjected to estimations of haematological parameters i. e. Haemoglobin concentration (Hb, packed cell volume (PCV, total erythrocyte count (TEC and Total leucocytes count (TLC using standard protocol. The haematological analysis showed statistically a significant (p<0.01 decreased levels of Hb, PCV, TEC and TLC in infected groups of cattle compared to infection free group cattle. This is probably the first systematic report in West Bengal, India. The result showed the haemoparasites have a negative impact on haematological parameters. This study may be useful in disease epidemiological map preparation, parasitic control policy preparation of the study areas.

  1. Multilayered analog optical differentiating device: performance analysis on structural parameters.

    Science.gov (United States)

    Wu, Wenhui; Jiang, Wei; Yang, Jiang; Gong, Shaoxiang; Ma, Yungui

    2017-12-15

    Analogy optical devices (AODs) able to do mathematical computations have recently gained strong research interest for their potential applications as accelerating hardware in traditional electronic computers. The performance of these wavefront-processing devices is primarily decided by the accuracy of the angular spectral engineering. In this Letter, we show that the multilayer technique could be a promising method to flexibly design AODs according to the input wavefront conditions. As examples, various Si-SiO 2 -based multilayer films are designed that can precisely perform the second-order differentiation for the input wavefronts of different Fourier spectrum widths. The minimum number and thickness uncertainty of sublayers for the device performance are discussed. A technique by rescaling the Fourier spectrum intensity has been proposed in order to further improve the practical feasibility. These results are thought to be instrumental for the development of AODs.

  2. Parameters affecting the performance of a low cost solar still

    International Nuclear Information System (INIS)

    Ahsan, A.; Imteaz, M.; Thomas, U.A.; Azmi, M.; Rahman, A.; Nik Daud, N.N.

    2014-01-01

    Highlights: • The triangular solar still is designed using cheap and durable materials. • The initial water depth has an inverse relationship with the production. • The water productivity is nearly proportional to the solar radiation. • The water quality parameters are within the accepted ranges of drinking water. - Abstract: This study aims at developing a low cost technique to be used in rural and coastal areas for converting saline water into potable water using solar energy. A triangular solar still (TrSS) was, therefore, designed and developed with cheap, lightweight, local and available materials. A number of field experiments were carried out to evaluate the effects of solar radiation intensity, ambient air temperature and the initial water depth on the daily water production of the TrSS. A time lag of about and hour between the hourly peaks of solar radiation and water production is observed. Finally, a few essential relationships were attained, e.g. between the daily production and the initial water depth, between the daily production and daily solar radiation, and between the daily production and the average ambient temperature. The effect of the initial water depth in the basin on the daily water productivity was evaluated by varying the water depths (1.5, 2.5 and 5 cm) with the climatic condition of Malaysia and an inverse proportional relationship was revealed between them. However, the daily water productivity is nearly proportional to the daily solar radiation. In addition, some important water quality parameters were tested in the laboratory to evaluate the distillate quality and were then compared with the drinking water standards

  3. Vaginal semisolid products: Technological performance considering physiologic parameters.

    Science.gov (United States)

    Machado, Rita Monteiro; Palmeira-de-Oliveira, Ana; Martinez-de-Oliveira, José; Palmeira-de-Oliveira, Rita

    2017-11-15

    Vaginal semisolid products are frequently used to treat vaginal infections and atrophy-related symptoms of menopause. Formulations composition and the methods for their characterization, especially those developed concerning the target epithelia, are key tools to predict in vivo results at early stages of product development. However, recent studies on this subject have been almost exclusively focused on anti-HIV preparations. The aim of this work consists on improving traditional characterization methods by using physiological parameters in order to construct predictive tools to characterize a new ideal vaginal semisolid formulation whatever target it may have. Ten vaginal antimicrobial and hormonal products already available in the market were studied (Gino-Canesten®, Sertopic®, Dermofix®, Gyno-pevaryl®, Lomexin®, Gino Travogen®, Dalacin V®, Ovestin®, Blissel®, Colpotrophine®). Furthermore, Universal Placebo gel and Replens® were used for comparison. Products were characterized in terms of: pH and buffering capacity in a vaginal fluid simulant (VFS); osmolality - directly and upon dilution in VFS; textural parameters (firmness, adhesiveness and bioadhesion) using vaginal ex vivo porcine epithelium; and viscosity (including VFS dilution at 37°C and after administration on an ex vivo model). Interestingly, the majority of the tested commercial vaginal formulations did not present technological characteristics close to the ideal ones when tested under target biological conditions. The inclusion of such methodologic adaptations is expected to optimize cost-efficiency of new formulations development by predicting efficacy and safety profiles at early stages of product development. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Specification of PWR UO2 pellet design parameters with the fuel performance code FRAPCON-1

    International Nuclear Information System (INIS)

    Silva, A.T.; Marra Neto, A.

    1988-08-01

    UO 2 pellet design parameters are analysed to verify their influence in the fuel basic properties and in its performance under irradiation in pressurized water reactors. Three groups of parameters are discussed: 1) content of fissionable and impurity materials; 2) stoichiometry; 3) density pore morpholoy, and microstructure. A methodology is applied with the fuel performance program FRAPCON-1 to specify these parameters. (author [pt

  5. Correlation between rotary drill performance parameters and borehole geophysical logging

    International Nuclear Information System (INIS)

    Scoble, M.J.; Peck, J.; Hendricks, C.

    1989-01-01

    There is a growing interest in developing performance monitoring techniques for both surface and underground mining equipment used in excavating, loading and transport systems. Research into the techniques and applications for monitoring drilling machinery including gamma and neutron logging, is reviewed. 17 refs.; 5 figs

  6. Effects of probiotics on growth performance, blood parameters, and ...

    African Journals Online (AJOL)

    Ziyanda Dlamini

    2017-09-25

    Sep 25, 2017 ... During this phase, the piglets have to cope with ... Pigs were kept individually in a temperature-controlled building in flat deck type ... Dilutions were subsequently plated in triplicate on selective agar media for enumeration of target bacterial ..... inactivated cells on the performance, microflora and blood ...

  7. Performance Analysis of Methods for Estimating Weibull Parameters ...

    African Journals Online (AJOL)

    The performance analysis revealed that the MLM was the most accurate model followed by the EPF and the GM. Furthermore, the comparison between the wind speed standard deviation predicted by the proposed models and the measured data showed that the MLM has a smaller relative error of -3.33% on average ...

  8. Assessment of non-genetic parameters of the racing performances ...

    African Journals Online (AJOL)

    s050186

    2012-10-02

    Oct 2, 2012 ... From 1995 to 2007, flat racing data was collected for Thoroughbred and Arabian horses in Algeria. Non- ... Performances are represented through the earnings and the rankings. Three traits were ... correlations (p < 0.001) between the three traits in the two breeds, showing that the measurements quantify ...

  9. Haematology and coagulation profiles in cats with congenital portosystemic shunts.

    Science.gov (United States)

    Tzounos, Caitlin E; Tivers, Michael S; Adamantos, Sophie E; English, Kate; Rees, Alan L; Lipscomb, Vicky J

    2017-12-01

    Objectives The objectives of this study were, first, to report the haematological parameters and coagulation times for cats with a congenital portosystemic shunt (CPSS) and the influence of surgical shunt attenuation on these parameters; and, second, to identify any association between prolongation in coagulation profiles and incidence of perioperative haemorrhage. Methods This was a retrospective clinical study using client-owned cats with a CPSS. Signalment, shunt type (extra- or intrahepatic), degree of shunt attenuation (complete or partial), haematological parameters, prothrombin time (PT) and activated partial thromboplastin time (aPTT) test results, and occurrence of any perioperative clinical bleeding complications were recorded for cats undergoing surgical treatment of a CPSS at the Royal Veterinary College, UK, between 1994 and 2011. Results Forty-two cats were included. Thirty-six (85.7%) had an extrahepatic CPSS and six (14.3%) had an intrahepatic CPSS. Preoperatively, mean cell volume (MCV) and mean cell haemoglobin (MCH) were below the reference interval (RI) in 32 (76.2%) and 31 (73.8%) cats, respectively. Red blood cell count and mean cell haemoglobin concentration (MCHC) were above the RI in 10 (23.8%) and eight (19.1%) cats, respectively. Postoperatively, there were significant increases in haematocrit ( P = 0.044), MCV ( P = 0.008) and MCH ( P = 0.002). Despite the significant increase in MCV postoperatively, the median MCV postoperatively was below the RI, indicating persistence of microcytosis. Preoperatively, PT was above the upper RI in 14 cats (87.5%), and aPTT was above the upper RI in 11 cats (68.8%). No cat demonstrated a perioperative clinical bleeding complication. Conclusions and relevance Cats with a CPSS are likely to present with a microcytosis, but rarely present with anaemia, leukocytosis or thrombocytopenia. Surgical attenuation of the CPSS results in a significant increase in the HCT and MCV. Coagulation profiles in cats with a

  10. Influence of Pyrolysis Parameters on the Performance of CMSM

    Directory of Open Access Journals (Sweden)

    Marta C. Campo

    2009-01-01

    Full Text Available Carbon hollow fiber membranes have been prepared by pyrolysis of a P84/S-PEEK blend. Proximate analysis of the precursor was performed using thermogravimetry (TGA, and a carbon yield of approximately 40% can be obtained. This study aimed at understanding the influence of pyrolysis parameters—end temperature, quenching effect, and soaking time—on the membrane properties. Permeation experiments were performed with N2, He, and CO2. Scanning electron microscopy (SEM has been done for all carbon hollow fibers. The highest permeances were obtained for the membrane submitted to an end temperature of 750°C and the highest ideal selectivities for an end temperature of 700°C. In both cases, the membranes were quenched to room temperature.

  11. The Performance Parameters Of Wireless Sensor Networks In Underground Mines

    Directory of Open Access Journals (Sweden)

    Sinan UGUZ

    2015-08-01

    Full Text Available In recent years underground mines have increasingly remained on the agenda with both difficult working conditions and problems such as collapsed and firedamp explosion in our country and in the world. In terms of life safety of miners and their health mine sites are required to be continuously monitored and controlled. This is difficult to achieve with existing wired systems due to the topography of mine sites. The applications have increased with the development of wireless sensor networks WSN technology in mine sites in recent years. This case has also caused an increase in studies on improving WSN performance. Especially energy efficiency is very important for the WSN hardware with a low energy source. In this study information about things to consider while using WSN technologies in underground mines and studies on their performance has been provided.

  12. FCC-ee accelerator parameters, performance and limitations

    CERN Document Server

    Koratzinos, Mike

    2016-12-22

    CERN has recently launched the Future Circular Collider (FCC) study to deal with all aspects of an ambitious post-LHC possible programme. The emphasis of the study is on a 100 TeV proton collider to be housed in a 80-100 km new ring in the Geneva region. An electron machine will also be considered as a possible intermediate first step (FCC-ee). The study benefits from earlier work done in the context of TLEP and has already published a parameter table, to serve as the basis for the work to be done. The study aims to publish a conceptual design report at around 2018. The recent discovery of a light Higgs boson has opened up considerable interest in circular e+e- Higgs factories around the world. FCC-ee is capable of very high luminosities in a wide centre-of-mass (ECM) spectrum from 90 to 350 GeV. This allows the very precise study of the Z, W and H bosons as well as the top quark, allowing for meaningful precision tests of the closure of the Standard Model.

  13. Performance of MarSite Multi parameter Borehole Instrumentation

    Science.gov (United States)

    Guralp, Cansun; Tunc, Suleyman; Ozel, Oguz; Meral Ozel, Nurcan; Necmioglu, Ocal

    2017-04-01

    In this paper we present two year results obtained from the integrated multiparameter borehole system at Marsite. The very broad band (VBB) system have been operating since installation in November 2014; one year in a water filled borehole and one year in a dry Borehole. from January 2016. The real time data has been available to the community. The two Borehole environments are compared showing the superior performance of dry borehole environ- ment compared to water filled for a very broad band (VBB) seismometer. The practical considerations applied in both borehole installations are compared and the best borehole practical installation techniques are presented and discussed. The data is also compared with a surface 120 second broad band sensor and the seismic arrays with in MarSite region. The very long term performance, (one year data in a dry hole) of the VBB Borehole seismometer and the Dilatometer will be presented The high frequency performance of the VBB seismometer which extends to 150 Hz and the dilatometer are compared characterizing the results from the dilatometer.

  14. Determination of the Performance Parameters of a Spectrophotometer: An Advanced Experiment.

    Science.gov (United States)

    Cope, Virgil W.

    1978-01-01

    Describes an advanced analytical chemistry laboratory experiment developed for the determination of the performance parameters of a spectrophotometer. Among the parameters are the baseline linearity with wavelength, wavelength accuracy and respectability, stray light, noise level and pen response time. (HM)

  15. MANAGEMENT OF HAEMATOLOGICAL PATIENTS TREATED WITHCARDIOTOXIC DRUG

    Directory of Open Access Journals (Sweden)

    Jure Dolenc

    2008-04-01

    Predisposing factors to cardiotoxicity should be taken into consideration when dealingwith such pacients. Careful history, clinical examination, electrocardiography, echocardiography and NT-proBNP measurement should be performed prior and at the end of thetreatment with cardiotoxic drugs. Pacients with slightest clinical, laboratory or echocardiographic parameters of developing heart failure should immediately be reffered to a cardiologist to start with appropriate treatment

  16. Immunological, clinical, haematological and oxidative responses to long distance transportation in horses.

    Science.gov (United States)

    Padalino, Barbara; Raidal, Sharanne Lee; Carter, Nicole; Celi, Pietro; Muscatello, Gary; Jeffcott, Leo; de Silva, Kumudika

    2017-12-01

    Horses are transported frequently and often over long distances. Transportation may represent a physiological stressor with consequential health and welfare implications. This study reports the effects of a long distance journey on immunological, clinical, haematological, inflammatory and oxidative parameters in an Experimental Group (EG) of ten horses, comparing them with six horses of similar age and breed used as a non-transported Control Group (CG). Clinical examination and blood sampling were performed twice on all horses: immediately after unloading for the EG, and at rest on the same day for the CG (day 1); at rest on the same day one week later for both groups (day 7). On day 1 EG horses showed increased heart and respiratory rates (Ptransportation induced an acute phase response impairing the cell-mediated immune response. Clinical examinations, including assessing CRT and body weight loss, and the monitoring of redox balance may be useful in evaluating the impact of extensive transport events on horses. A better understanding of the link between transportation stress, the immune system and the acute phase response is likely to inform strategies for enhancing the welfare of transported horses. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Gaucher disease: haematological presentations and complications.

    Science.gov (United States)

    Thomas, Alison S; Mehta, Atul; Hughes, Derralynn A

    2014-05-01

    Gaucher disease (GD) is an autosomal recessive lysosomal storage disease, caused by deficiency of the enzyme glucocerebrosidase, required for the degradation of glycosphingolipids. Clinical manifestations include hepatosplenomegaly, thrombocytopenia, bone disease and a bleeding diathesis, frequently resulting in presentation to haematologists. Historically managed by splenectomy, transfusions and orthopaedic surgery, the development of specific therapy in the form of intravenous enzyme replacement therapy in the 1990s has resulted in dramatic improvements in haematological and visceral disease. Recognition of complications, including multiple myeloma and Parkinson disease, has challenged the traditional macrophage-centric view of the pathophysiology of this disorder. The pathways by which enzyme deficiency results in the clinical manifestations of this disorder are poorly understood; altered inflammatory cytokine profiles, bioactive sphingolipid derivatives and alterations in the bone marrow microenvironment have been implicated. Further elucidating these pathways will serve to advance our understanding not only of GD, but of associated disorders. © 2014 John Wiley & Sons Ltd.

  18. Effects of dietary administration of stinging nettle (Urtica dioica) on the growth performance, biochemical, hematological and immunological parameters in juvenile and adult Victoria Labeo (Labeo victorianus) challenged with Aeromonas hydrophila.

    Science.gov (United States)

    Ngugi, Charles C; Oyoo-Okoth, Elijah; Mugo-Bundi, James; Orina, Paul Sagwe; Chemoiwa, Emily Jepyegon; Aloo, Peninah A

    2015-06-01

    We investigated effects of dietary administration of stinging nettle (Urtica dioica) on growth performance, biochemical, hematological and immunological parameters in juvenile and adult Victoria Labeo (Labeo victorianus) against Aeromonas hydrophila. Fish were divided into 4 groups and fed for 4 and 16 weeks with 0%, 1%, 2% and 5% of U. dioica incorporated into the diet. Use of U. dioica in the diet resulted in improved biochemical, hematological and immunological parameters. Among the biochemical parameters; plasma cortisol, glucose, triglyceride and cholesterol decreased while total protein and albumin in fish increased with increasing dietary inclusion of U. dioica. Among the haematology parameters: red blood cell (RBC), white blood cell (WBC) counts, haematocrit (Htc), mean cell haemoglobin (MCH), mean cell haemoglobin concentration (MCHC) and netrophiles increased with increasing dietary inclusion levels of U. dioica, some depending on the fish age. Serum immunoglobulins, lysozyme activity and respiratory burst were the main immunological parameters in the adult and juvenile L. victorianus measured and they all increased with increasing herbal inclusion of U. dioica in the diet. Dietary incorporation of U. dioica at 5% showed significantly higher relative percentage survival (up to 95%) against A. hydrophila. The current results demonstrate that using U. dioica can stimulate fish immunity and make L. victorianus more resistant to bacterial infection (A. hydrophila). Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. The Parameters Selection of PSO Algorithm influencing On performance of Fault Diagnosis

    Directory of Open Access Journals (Sweden)

    He Yan

    2016-01-01

    Full Text Available The particle swarm optimization (PSO is an optimization algorithm based on intelligent optimization. Parameters selection of PSO will play an important role in performance and efficiency of the algorithm. In this paper, the performance of PSO is analyzed when the control parameters vary, including particle number, accelerate constant, inertia weight and maximum limited velocity. And then PSO with dynamic parameters has been applied on the neural network training for gearbox fault diagnosis, the results with different parameters of PSO are compared and analyzed. At last some suggestions for parameters selection are proposed to improve the performance of PSO.

  20. Ultrasound for Appendicitis: Performance and Integration with Clinical Parameters

    Science.gov (United States)

    Löfvenberg, Fanny

    2016-01-01

    Objective. To evaluate the performance of ultrasound in pediatric appendicitis and the integration of US with the pediatric appendicitis score (PAS) and C-reactive protein (CRP). Method. An institution-based, retrospective study of children who underwent abdominal US for suspected appendicitis between 2012 and 2015 at a tertiary pediatric surgery center. US results were dichotomized, with a nonvisualized appendix considered as a negative examination. Results. In total, 438 children were included (mean 8.5 years, 54% boys), with an appendicitis rate of 29%. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for US were 82%, 97%, 92%, and 93%, respectively, without significant age or gender differences. Pediatric radiologists had significantly higher sensitivity compared to general radiologists, 88% and 71%, respectively (p appendicitis, regardless of age or gender, and should be the first choice of imaging modalities. Combining US with PAS and CRP may reduce several unnecessary admissions for in-hospital observation. PMID:28044133

  1. Anorectal complications in patients with haematological malignancies.

    Science.gov (United States)

    Loureiro, Rafaela V; Borges, Verónica P; Tomé, Ana L; Bernardes, Carlos F; Silva, Mário J; Bettencourt, Maria J

    2018-04-13

    Anorectal complications are common in patients with haematological malignancies. The objectives are to characterize anorectal complications in these patients, identify risk factors and shed light on treatment, morbidity and mortality rates. A retrospective, observational study that included 83 inpatients with haematological malignancies and proctological symptoms from January 2010 to September 2015 was conducted. Clinical outcomes were obtained through a detailed review of medical records. The median age was 56 years, and 52 (62.7%) patients were men. Fifty-six (67.5%) patients had nonseptic anorectal complications and 27 (32.5%) patients had septic anorectal complications. Patients with septic anorectal complications were more commonly male, older, and had lower absolute neutrophil counts, but the differences were not statistically significant (P=0.79, 0.67 and 0.89, respectively). In positive blood cultures [23/70 (32.9%)], Enterococcus faecium, Klebsiella pneumonia, and Escherichia coli were the most common isolated agents. In nonseptic anorectal complications, conservative treatments/minor proctological procedures were adopted, and patients with septic anorectal complications were treated with antibiotics±major proctological procedures and/or surgical drainage/debridement. Forty-eight (85.7%) patients in the nonseptic complications group improved compared with 23 (85.2%) patients in the septic complications group. The overall mortality rate was 2.4% (n=2), with one (1.2%) death related to perianal sepsis. Enterococcus spp. were more commonly identified in this study and can be increasing in this specific population. In contrast to other reports, we did not identify an association between septic anorectal complications and possible risk factors such as male sex, younger age or a low absolute neutrophil count. Most patients had nonseptic anorectal complications. A major proctological procedure/surgical debridement should always be applied in septic complications

  2. Haematological and serum biochemical reference values in free-ranging red deer (Cervus elaphus atlanticus

    Directory of Open Access Journals (Sweden)

    Olav Rosef

    2004-04-01

    Full Text Available Analyses of haematological and biochemical constituents were carried out on the Norwegian subspecies of free-ranging red deer (Cervus elaphus atlanticus. All animals were captured from January to March by using a mixture of xylazine and tiletamin-zolazepam. Immobilisation was performed with plastic projectile syringes fired from a dart gun. Fourteen haematological parameters were analysed. There were no differences in the values between hinds and stags and between adults and calves (P > 0.01. Of the 22 biochemical compounds investigated there was a significant difference (P < 0.01 between calves and adults for lactate dehydrogenase (LD, globulin, beta globulin, gamma globulin, and the minerals Na, K, Mg, Zn, Ca, and P. Differences (P < 0.01 between hinds and stags were found in cholesterol, gamma glutamyl transferase (GGT, alpha-1 globulin, alpha-2 globulin and Cu. The blood values determined in this study can be used as reference values for this red deer subspecies immobilised with a mixture of xylazine-tiletamin-zolazepam for health control and diagnosis of diseases.Abstract in Norwegian /Sammendrag:Hematologiske og biokjemiske parametere er analysert på norsk frittlevende hjort (Cervus elaphus atlanticus. Hjorten ble immobilisert i tidsrommet januar til mars ved hjelp av et spesialgevær ladet med plast kanyler som inneholdt en blanding av xylazin og tiletamin-zolazepam. Det var ingen forskjeller i de14 undersøkte hematologiske verdiene mellom hinder, kalver og bukker (P>0,01. Av de 22 biokjemiske parametrene som ble undersøkt var det en signifikant forskjell mellom kalver og voksne (P<0,01 når det gjelder laktat dehydrogenase, globulin, beta globulin, gamma globulin og mineralene Na, K, Mg, Zn, Ca og P. Det var en signifikant forskjell mellom hinder og bukker (P<0.01 på parametrene kolesterol, gamma glutamyl transferase, alfa-1 globulin, alfa-2 globulin og Cu. Blodverdiene som ble målt i dette studiet kan bli brukt som referanseverdier

  3. [Research and Design of a System for Detecting Automated External Defbrillator Performance Parameters].

    Science.gov (United States)

    Wang, Kewu; Xiao, Shengxiang; Jiang, Lina; Hu, Jingkai

    2017-09-30

    In order to regularly detect the performance parameters of automated external defibrillator (AED), to make sure it is safe before using the instrument, research and design of a system for detecting automated external defibrillator performance parameters. According to the research of the characteristics of its performance parameters, combing the STM32's stability and high speed with PWM modulation control, the system produces a variety of ECG normal and abnormal signals through the digital sampling methods. Completed the design of the hardware and software, formed a prototype. This system can accurate detect automated external defibrillator discharge energy, synchronous defibrillation time, charging time and other key performance parameters.

  4. CLINICO-HAEMATOLOGICAL STUDY OF PANCYTOPENIA IN A TERTIARY CARE CENTRE

    Directory of Open Access Journals (Sweden)

    Sanapala Sridevi

    2018-01-01

    Full Text Available BACKGROUND Pancytopenia is one of the pathological manifestation resulting from various underlying disease processes affecting the bone marrow. Hence, bone marrow examination is the diagnostic tool to detect the underlying aetiology of pancytopenia. Pancytopenia nowadays has become a relatively common haematological entity. The underlying cause is ranging from simple drug-induced bone marrow hypoplasia, megaloblastic anaemia to fatal bone marrow aplasias and leukaemias. Thus, identification of the correct cause will help in implementing appropriate therapy. MATERIALS AND METHODS This was a prospective study and 158 pancytopenic patients were evaluated clinically along with haematological parameters and bone marrow aspiration in Clinical Pathology, Department of Pathology, during the period of December 2016 to December 2017. RESULTS Among 158 cases, age of patients ranged from 3 to 88 years with a mean age of 45 years and male predominance. Most of the patients presented with fever and anaemia. The commonest physical finding was pallor followed by generalised weakness and splenomegaly. Dimorphic anaemia was the predominant blood picture. Among the 158 cases, 56 cases have undergone bone marrow aspiration in the department. The commonest bone marrow finding was erythroid hyperplasia with megaloblastic maturation (25%. CONCLUSION The present study shows the detailed primary haematological investigations along with bone marrow aspiration in pancytopenia patients, which is useful in understanding disease process. These are also helpful in planning further evaluation and management.

  5. haematological profiles of pigs raised under intensive management

    African Journals Online (AJOL)

    EZE J I

    values obtained could be used as reference values for pigs in South-eastern Nigeria. The clinical importance of the ... Key words: haematology, pigs, intensive management, south-eastern Nigeria ..... Medicine: A textbook of Diseases of Cattle ...

  6. Season, sex and age variation in the haematology and body ...

    African Journals Online (AJOL)

    Body condition and haematological indices provide powerful information when assessing wildlife health. Reference intervals for these indices can facilitate wildlife management, and would benefit initiatives to save the Critically Endangered geometric tortoise (Psammobates geometricus). We collected data from 126 ...

  7. Haematological, ocular and skeletal abnormalities in a Samoyed family

    International Nuclear Information System (INIS)

    Aroch, I.; Ofri, R.; Aizenberg, I.

    1996-01-01

    Haematological, ocular and skeletal abnormalities were documented in a samoyed male and its five offspring. Haematological abnormalities, found in repeated tests in all the dogs, included marked eosinophilia, eosinophilic bands and absence of Barr bodies. Two of the dogs had bilateral buphthalmia, retinal detachments and other ocular abnormalities. Three of the dogs had skeletal abnormalities including chondrodysplasia (dwarfism) and brachygnathia (undershot jaw). A similar combination of inherited skeletal and ocular disorders, without the haematological abnormalities, has been described in samoyeds. Acquired causes for the haematological findings, which are similar to the inherited Pelger-Huët anomaly described in several species, have been eliminated. Eosinophilic bands and scarcity of Barr bodies could be a marker, or a previously unreported manifestation, of an inherited disorder in samoyeds

  8. Effects of zinc exposure on the accumulation, haematology and ...

    African Journals Online (AJOL)

    Effects of zinc exposure on the accumulation, haematology and immunology of Mozambique tilapia, Oreochromis mossambicus. Ekrem Şanver Çelik, Hasan Kaya, Sevdan Yilmaz, Mehmet Akbulut, Arınç Tulgar ...

  9. A Review of the Biochemical and Haematological Effects of Caffeine ...

    African Journals Online (AJOL)

    A Review of the Biochemical and Haematological Effects of Caffeine. ... be found in different food and drinks which includes; coffee, tea, chocolate, beverages, ... when taken in excess over a period of time can result in adverse health hazards.

  10. Haematological and serum biochemical profiles of broiler chickens ...

    African Journals Online (AJOL)

    MOLM) on the haematological and serum biochemical profile of broiler chickens. Fresh Moringa leaves (FML) were shade-dried for four days and milled into meal. A total of two hundred broilers unsexed chickens (Anak strain) were randomly ...

  11. Effects of Zinc Exposure on Accumulation, Haematology and ...

    African Journals Online (AJOL)

    BILGISAYAR1

    2013-02-13

    Feb 13, 2013 ... haematology and immunology of Mozambique tilapia,. Oreochromis mossambicus .... total volume. The fish were fed with fish food during the adaptation ..... white blood cells at different concentrations in humans and animals ...

  12. Assessment of the haematological indices of albino rats fed diets ...

    African Journals Online (AJOL)

    Keywords: Haematology, jackfruit, bulb, seed, supplementation. INTRODUCTION ... Albokhadaim, 2015) and humans (Lavy,. 1994 .... Table 2: Body weights and daily food intake of control and rats fed jackfruit seed diet (g). Experimental.

  13. Auto-immune haematological complications occurring during the ...

    African Journals Online (AJOL)

    Auto-immune haematological complications occurring during treatment for malignant Iymphoproliferative diseases are described in 5 patients. There appeared to be a temporal relationship between the development of these complications and the administration of chemotherapeutic drugs or extensive radiotherapy.

  14. Nutrient Retention and Haematological Indices of Broiler Starters ...

    African Journals Online (AJOL)

    acer

    2National Animal Production Research Institute, Shika, Ahmadu Bello University, Zaria. 285. ABSTRACT: .... Completely Randomized Design and means .... Jain, N. C. (1993). Essentials of Veterinary. Haematology, 4th ed. Lea and Febiger,.

  15. Real-world costs of autologous and allogeneic stem cell transplantations for haematological diseases: a multicentre study.

    NARCIS (Netherlands)

    Blommestein, H.M.; Verelst, S.G.; Huijgens, P.C.; Blijlevens, N.M.A.; Cornelissen, J.J.; Uyl-de Groot, C.A.

    2012-01-01

    Haematopoietic stem cell transplantation (SCT) is an expensive lifesaving procedure, which is increasingly performed in patients with haematological diseases. Developments in the protocol for SCT have resulted in cost estimates that require updating. We aimed to calculate actual costs for SCT and to

  16. Pharmacists’ Interventions in A Paediatric Haematology-Oncology Pharmacy: Do They Matter to Minimise Medication Misadventure?

    Directory of Open Access Journals (Sweden)

    Hesty U. Ramadaniati

    2016-03-01

    Full Text Available Paediatric patients with cancer are a high-risk patient population for medication misadventures. This study aimed to document and evaluate the role of pharmacists’ interventions during dispensing-related activities in minimising the occurrence of medication misadventure in haematology-oncology patients. The primary investigator observed and documented all clinical interventions during dispensing-related activities performed by clinical pharmacists in a haematology-oncology pharmacy during 33-day. A total of 359 interventions were performed for 1028 patients. The rates of intervention were 20.04 per 100 medication orders and 34.92 per 100 patients. Provision of drug information was the most common interventions constituting more than three quarters of all interventions. According to therapeutic groups, cytotoxic antineoplastics made up more than half of all interventions. Of all interventions, 22 involved recommendations leading to changes in patients’ treatment (active interventions, and all recommendations were accepted. The top three medication errors were due to inappropriate dosing, labelling error, and unfulfilled indication. Clinical pharmacists’ intervention during dispensing in a paediatric haematology-oncology pharmacy improved medication safety and patient care by minimising the incidence of medication misadventures.

  17. Effect analysis of geometric parameters of floating raft on isolation performance

    Directory of Open Access Journals (Sweden)

    LI Shangda

    2017-12-01

    Full Text Available [Objectives] This paper focuses on the effects of the geometric parameters of a floating raft on isolation performance.[Methods] Based on the idea that the weight of a floating raft remains constant, a parametric finite element model is established using geometric parameters, and the effects of the geometric parameters when isolation performance is measured by vibration level difference are discussed.[Results] The effects of the geometric parameters of a floating raft on isolation performance are mainly reflected in the middle and high frequency areas. The most important geometric parameters which have an impact on isolation performance are the raft's height, length to width ratio and number of ribs. Adjusting the geometric parameters of the raft is one effective way to avoid the vibration frequency of mechanical equipment.[Conclusions] This paper has some practical value for the engineering design of floating raft isolation systems.

  18. Parameter Selection and Performance Analysis of Mobile Terminal Models Based on Unity3D

    Institute of Scientific and Technical Information of China (English)

    KONG Li-feng; ZHAO Hai-ying; XU Guang-mei

    2014-01-01

    Mobile platform is now widely seen as a promising multimedia service with a favorable user group and market prospect. To study the influence of mobile terminal models on the quality of scene roaming, a parameter setting platform of mobile terminal models is established to select the parameter selection and performance index on different mobile platforms in this paper. This test platform is established based on model optimality principle, analyzing the performance curve of mobile terminals in different scene models and then deducing the external parameter of model establishment. Simulation results prove that the established test platform is able to analyze the parameter and performance matching list of a mobile terminal model.

  19. Haematological values for captive harpy eagle (Harpia harpyja

    Directory of Open Access Journals (Sweden)

    Marcos J. Oliveira

    2014-08-01

    Full Text Available Decreasing of harpy eagle (Harpia harpyja populations in natural environments, mainly in non-preserved areas, makes captive population management an important contribution to genetic diversity conservation. The aim of this study is to evaluate hematological parameters for captive harpy eagles maintained at the wild animals breeding center of Itaipu Binacional, Paraná State, Brazil. Fourteen blood samples from nine harpy eagles were collected from animals of both sexes, of different ages and with no clinical signs of disease. Significant variations were found in haematological values of hematocrit, hemoglobin, mean corpuscular hemoglobin (MCH, mean corpuscular hemoglobin concentration (MCHC, leukocyte, a relative number of heterophils, absolute and relative number of lymphocytes, monocytes, eosinophils, basophils and plasma protein between groups of young (less than six months old and adult birds. Comparing males and females there was variation in the values of erythrocytes, hemoglobin, mean corpuscular volume (MCV, mean corpuscular hemoglobin (MCH on heterophils, absolute and relative number of lymphocytes, eosinophils and basophils. There was also variation in the values of red blood cells, hematocrit, hemoglobin, mean corpuscular volume (MCV, mean corpuscular hemoglobin (MCH, mean corpuscular hemoglobin concentration (MCHC, leukocyte count, absolute number of lymphocytes, eosinophils and basophils among birds that study compared to another reference birds. Due to the limited information available on harpy eagle hematology, this study will be useful to the clinical assessment of birds maintained in captivity.

  20. Extraction of bowing parameters from violin performance combining motion capture and sensors.

    Science.gov (United States)

    Schoonderwaldt, E; Demoucron, M

    2009-11-01

    A method is described for measurement of a complete set of bowing parameters in violin performance. Optical motion capture was combined with sensors for accurate measurement of the main bowing parameters (bow position, bow velocity, bow acceleration, bow-bridge distance, and bow force) as well as secondary control parameters (skewness, inclination, and tilt of the bow). In addition, other performance features (moments of on/off in bow-string contact, string played, and bowing direction) were extracted. Detailed descriptions of the calculations of the bowing parameters, features, and calibrations are given. The described system is capable of measuring all bowing parameters without disturbing the player, allowing for detailed studies of musically relevant aspects of bow control and coordination of bowing parameters in bowed-string instrument performance.

  1. Haematology and Clinical Biochemistry Findings Associated with Equine Diseases - a Review

    Directory of Open Access Journals (Sweden)

    Onyinyechukwu A. AGINA

    2017-03-01

    Full Text Available The course and outcome of a disease process is dependent upon factors such as the disease-causing agent and its cell tropism, defense mechanisms of the host, genetic resistance of the species or breed affected, as well as the age, nutritional status and hormonal levels of the affected animal. When haematology, clinical biochemistry and cytology test results are combined with other laboratory procedures, complete physical examination and also with the history of the patient, a veterinarian is well armed to arrive at a definitive diagnosis, make a certain prognosis (good, poor or guarded and can also make a concluding statement on the efficacy of the instituted therapy. In clinical biochemistry, demonstration of specific enzyme activity and concentration of analytes in serum/plasma facilitates the disease diagnosis. Also, evaluation of haematology, clinical biochemistry and diagnostic cytology tests can help establish the presence or absence of diseases of internal organs, and by serial performance of these tests, may help to determine whether a disease process remains static, progressive or regressive. This review therefore provides the haematological, serum biochemical and cytological characteristics of diseases caused by the main bacteria, viruses, fungi, protozoa, helminths, arthropods, nutritional deficiencies, endocrine disturbances, neoplasm, allergy, toxins (phytoxins and zootoxins and inorganic poisons in horses.

  2. Increasing the Performance and Reliability of Power Boiler by Monitoring Thermal and Strength Parameters

    Directory of Open Access Journals (Sweden)

    Sobota Tomasz

    2017-01-01

    Full Text Available The paper presents a method for determination of thermo-flow parameters for steam boilers. This method allows to perform the calculations of the boiler furnace chamber and heat flow rates absorbed by superheater stages. These parameters are important for monitoring the performance of the power unit. Knowledge of these parameters allows determining the degree of the furnace chamber slagging. The calculation can be performed in online mode and use to monitoring of steam boiler. The presented method allows to the operation of steam boiler with high efficiency.

  3. Haematological values of three Antarctic penguins: gentoo (Pygoscelis papua, Adélie (P. adeliae and chinstrap (P. antarcticus

    Directory of Open Access Journals (Sweden)

    Andrés E. Ibañez

    2015-06-01

    Full Text Available It is established that haematological and biochemical parameters provide important data to assess the physiological condition and health status of wild birds. To undertake conservation physiology or ecophysiology work, it is therefore essential to establish baseline physiological parameters and how these parameters change with age and life history events. In this work, we determined and compared baseline haematology and serum biochemistry between adults and chicks of three Antarctic penguin species of the genus Pygoscelis: gentoo (P. papua, Adélie (P. adeliae and chinstrap (P. antarcticus. Differences in adults among species were observed in haemoglobin and biochemical parameters such as total proteins, glucose and alkaline phosphatase activity. In addition, differences between adults and chicks in haematocrit, haemoglobin, total proteins and glucose concentration were determined. Moreover, we evaluated the electrophoretic protein profiles between adults and chicks of the genus Pygoscelis, and a conserved protein pattern was observed among species and ages in the genus. Altogether, the results suggest that biochemical and haematological differences among pygoscelids may be related to the nutritional status and energetic expenditure during breeding as well as their feeding habits and development stage.

  4. Aerobic physical exercise for adult patients with haematological malignancies.

    Science.gov (United States)

    Bergenthal, Nils; Will, Andrea; Streckmann, Fiona; Wolkewitz, Klaus-Dieter; Monsef, Ina; Engert, Andreas; Elter, Thomas; Skoetz, Nicole

    2014-11-11

    Although people with haematological malignancies have to endure long phases of therapy and immobility which is known to diminish their physical performance level, the advice to rest and avoid intensive exercises is still common practice. This recommendation is partly due to the severe anaemia and thrombocytopenia from which many patients suffer. The inability to perform activities of daily living restricts them, diminishes their quality of life and can influence medical therapy. To evaluate the efficacy, safety and feasibility of aerobic physical exercise for adults suffering from haematological malignancies. We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, 2014, Issue 1) and MEDLINE (1950 to January 2014) as well as conference proceedings for randomised controlled trials (RCTs). We included RCTs comparing an aerobic physical exercise intervention, intending to improve the oxygen system, in addition to standard care with standard care only for adults suffering from haematological malignancies. We also included studies that evaluated aerobic exercise in addition to strength training. We excluded studies that investigated the effect of training programmes that were composed of yoga, tai chi chuan, qigong or similar types of exercise. We also excluded studies exploring the influence of strength training without additive aerobic exercise. Additionally, we excluded studies assessing outcomes without any clinical impact. Two review authors independently screened search results, extracted data and assessed the quality of trials. We used risk ratios (RRs) for adverse events and 100-day survival, standardised mean differences for quality of life (QoL), fatigue, and physical performance, and mean differences for anthropometric measurements. Our search strategies identified 1518 potentially relevant references. Of these, we included nine RCTs involving 818 participants. The potential risk of bias in these trials is unclear, due

  5. A new unbiased stochastic derivative estimator for discontinuous sample performances with structural parameters

    NARCIS (Netherlands)

    Peng, Yijie; Fu, Michael C.; Hu, Jian Qiang; Heidergott, Bernd

    In this paper, we propose a new unbiased stochastic derivative estimator in a framework that can handle discontinuous sample performances with structural parameters. This work extends the three most popular unbiased stochastic derivative estimators: (1) infinitesimal perturbation analysis (IPA), (2)

  6. ZYGOMYCOSIS IN IMMUNOCOMPROMISED NON-HAEMATOLOGICAL PATIENTS

    Directory of Open Access Journals (Sweden)

    George Petrikkos

    2011-03-01

    Full Text Available Zygomycoses are rare emerging diseases with a high fatality rate.  The most important risk factors include neutropenia or functional neutropenia, diabetic ketoacidosis, iron overload, major trauma, prolonged use of corticosteroids, illicit intravenous drug use, neonatal prematurity, malnourishment, and pre-exposure to antifungal agents with no activity against zygomycetes, such as voriconazole and caspofungin. A high index of suspicion is crucial for the diagnosis, as prompt and appropriate management can considerably reduce morbidity and mortality. Suspicion index can be increased through recognition of the differential patterns of clinical presentation. In the non- haematological immunocompromised patients, zygomycosis can manifest in various clinical forms, depending on the underlying condition: mostly as rhino-orbital or rhino-cerebral in diabetes patients, pulmonary infection in patients with malignancy or solid organ transplantation, disseminated infection in iron overloaded or deferoxamine treated patients, cerebral - with no sinus involvement - in ID users, gastrointestinal in premature infants or malnourishment, and cutaneous after direct inoculation in immunocompetent individuals with trauma or burns. Treating a patient’s underlying medical condition and reducing immunosuppression are essential to therapy. Rapid correction of metabolic abnormalities is mandatory in cases such as uncontrolled diabetes and corticosteroids or other immunosuppressive drugs should be discontinued where feasible. AmphotericinB or its newer and less toxic lipid formulations are the drugs of choice regarding antifungal chemotherapy, while extensive surgical debridemend is essential to reduce infected and necrotic tissue. A high number of cases could be prevented through measures including diabetes control programmes and proper pre- and post-surgical hygiene.

  7. Haematology, genotoxicity, enzymatic activity and histopathology as biomarkers of metal pollution in the shrew Crocidura russula

    International Nuclear Information System (INIS)

    Sanchez-Chardi, A.; Marques, C.C.; Gabriel, S.I.; Capela-Silva, F.; Cabrita, A.S.; Lopez-Fuster, M.J.; Nadal, J.; Mathias, M.L.

    2008-01-01

    Haematological (WBC, RBC, Hgb and Hct) and genotoxicity (MNT) parameters, hepatic enzymatic activities (GST, GPx and GR), and a histopathological evaluation of liver, kidneys and gonads were assessed as general biomarkers of metal pollution in the shrew Crocidura russula inhabiting a pyrite mining area. Specimens exposed to metals presented a few significant alterations when compared with reference animals: GST activity decreased; micronuclei increased; and evident liver alterations related to metal exposure were observed. On the basis of all the parameters studied, age was an important factor that partly explained the observed variation, whereas sex was the least important factor. Significant correlations were also found between heavy metal concentrations and biomarkers evaluated, demonstrating the great influence of these metals in the metabolic alterations. To the best of our knowledge, these data constitute the first measurements of a battery of biomarkers in shrews from a mine site and are among the few available for insectivorous mammals. - Metals from an abandoned pyrite mine produce alterations in haematological parameters, GST, MNT, and histopathology in shrews

  8. Haematological and biochemical reference values for healthy adults in the middle belt of Ghana.

    Directory of Open Access Journals (Sweden)

    David K Dosoo

    Full Text Available Reference values are very important in clinical management of patients, screening participants for enrollment into clinical trials and for monitoring the onset of adverse events during these trials. The aim of this was to establish gender-specific haematological and biochemical reference values for healthy adults in the central part of Ghana.A total of 691 adults between 18 and 59 years resident in the Kintampo North Municipality and South District in the central part of Ghana were randomly selected using the Kintampo Health and Demographic Surveillance System and enrolled in this cross-sectional survey. Out of these, 625 adults made up of 316 males and 309 females were assessed by a clinician to be healthy. Median values and nonparametric 95% reference values for 16 haematology and 22 biochemistry parameters were determined for this population based on the Clinical Laboratory and Standards Institute guidelines. Values established in this study were compared with the Caucasian values being used currently by our laboratory as reference values and also with data from other African and western countries.REFERENCE VALUES ESTABLISHED INCLUDE: haemoglobin 113-164 g/L for males and 88-144 g/L for females; total white blood cell count 3.4-9.2 × 10(9/L; platelet count 88-352 × 10(9/L for males and 89-403 × 10(9/L for females; alanine aminotransferase 8-54 U/L for males and 6-51 U/L for females; creatinine 56-119 µmol/L for males and 53-106 µmol/L for females. Using the haematological reference values based on the package inserts would have screened out up to 53% of potential trial participants and up to 25% of the population using the biochemical parameters.We have established a panel of locally relevant reference parameters for commonly used haematological and biochemical tests. This is important as it will help in the interpretation of laboratory results both for clinical management of patients and safety monitoring during a trial.

  9. Effect of dietary supplementation of probiotics and enzymes on the haematology of rabbits reared under two housing systems

    Directory of Open Access Journals (Sweden)

    Sarat Chandra Amaravadhi

    Full Text Available Aim : To study the influence of housing system and dietary supplementation of probiotics and enzymes on haematological parameters of rabbits. Materials and Methods: A total of 144 weaned rabbits were divided into 2 groups of 72 in each group and housed under conventional cage system and backyard system. The rabbits in each housing system were divided into 4 groups of 18 in each group and the diets were supplemented with probiotics, enzymes and both. Results: The housing system and supplementation of probiotics and enzymes did not exert significant influence on any of the haematological parameters studied. However, there was slight positive influence of probiotic and enzyme supplementation on the health status of rabbits as revealed by haematological parameters. The overall mean Total erythrocyte count, total leucocyte count, lymphocytes, neutrophils, eosinophils, monocytes, haemoglobin and packed cell volume were 7.52, 6.29 (103/mm3, 60.27%, 35.71%, 1.35%, 1.92%, 10.67 g/dl and 34.25%, respectively. Conclusion: Rabbits can be reared on low input backyard system without any adverse effect on health and supplementation of probiotics and enzymes had a positive influence on health status of rabbits. [Vet World 2012; 5(12.000: 748-753

  10. Human comfort and self-estimated performance in relation to indoor environmental parameters and building features

    DEFF Research Database (Denmark)

    Frontczak, Monika Joanna

    The main objective of the Ph.D. study was to examine occupants’ perception of comfort and self-estimated job performance in non-industrial buildings (homes and offices), in particular how building occupants understand comfort and which parameters, not necessarily related to indoor environments...... and storage, noise level and visual privacy. However, if job performance is considered, then satisfaction with the main indoor environmental parameters should be addressed first as they affected self-estimated job performance to the highest extent. The present study showed that overall satisfaction...... with personal workspace affected significantly the self-estimated job performance. Increasing overall satisfaction with the personal workspace by about 15% would correspond to an increase of self-estimated job performance by 3.7%. Among indoor environmental parameters and building features, satisfaction...

  11. Haematological emergencies managing hypercalcaemia in adults and children with haematological disorders.

    LENUS (Irish Health Repository)

    Sargent, Jeremy T S

    2012-02-01

    Hypercalcaemia is a common metabolic complication of malignant disease often requiring emergency intervention. Although it is more frequently associated with solid tumours, malignancy-associated hypercalcaemia (MAH) is seen in a significant number of patients with blood diseases. Its association with myeloma and adult T-cell leukaemia\\/lymphoma is well recognized but the incidence of hypercalcaemia in other haematological neoplasms, affecting adults and children, is less clearly defined. Haematologists need to be familiar with the clinical manifestations of, the differential diagnosis to be considered and the most effective management strategies that are currently available for MAH. The key components of management of MAH include aggressive rehydration, specific therapy to inhibit bone resorption and, crucially, treatment of the underlying malignancy. Bisphosphonates have revolutionized the management of MAH over the last 20 years, however the elucidation of molecular pathways implicated in MAH is facilitating the development of more targeted approaches to treatment.

  12. Drug- not carrier-dependent haematological and biochemical changes in a repeated dose study of cyclosporine encapsulated polyester nano- and micro-particles: Size does not matter

    International Nuclear Information System (INIS)

    Venkatpurwar, V.P.; Rhodes, S.; Oien, K.A.; Elliott, M.A.; Tekwe, C.D.; Jørgensen, H.G.; Kumar, M.N.V. Ravi

    2015-01-01

    Highlights: • The particulate delivery allows an increase in dose range without accrual of toxicities. • The altered haematological and biochemical changes are drug, but not particle dependent. • PLGA nano/microparticles are safe on subacute peroral dosing over 28 days. • Nano-toxicology, drug needs to be considered. - Abstract: Biodegradable nanoparticles are being considered more often as drug carriers to address pharmacokinetic/pharmacodynamic issues, yet nano-product safety has not been systematically proven. In this study, haematological, biochemical and histological parameters were examined on 28 day daily dosing of rats with nano- or micro-particle encapsulated cyclosporine (CsA) to confirm if any changes observed were drug or carrier dependent. CsA encapsulated poly(lactide-co-glycolide) [PLGA] nano- (nCsA) and micro-particles (mCsA) were prepared by emulsion techniques. CsA (15, 30, 45 mg/kg) were administered by oral gavage to Sprague Dawley (SD) rats over 28 days. Haematological and biochemical metrics were followed with tissue histology performed on sacrifice. Whether presented as nCsA or mCsA, 45 mg/kg dose caused significant loss of body weight and lowered food consumption compared to untreated control. Across the doses, both nCsA and mCsA produce significant decreases in lymphocyte numbers compared to controls, commensurate with the proprietary product, Neoral ® 15. Dosing with nCsA showed higher serum drug levels than mCsA presumably owing to the smaller particle size facilitating absorption. The treatment had no noticeable effects on inflammatory/oxidative stress markers or antioxidant enzyme levels, except an increase in ceruloplasmin (CP) levels for high dose nCsA/mCsA group. Further, only subtle, sub-lethal changes were observed in histology of nCsA/mCsA treated rat organs. Blank (drug-free) particles did not induce changes in the parameters studied. Therefore, it is extremely important that the encapsulated drug in the nano-products is

  13. Effect of the infection with the nematode Haemonchus contortus (Strongylida: Trichostrongylidae on the haematological, biochemical, clinical and reproductive traits in rams

    Directory of Open Access Journals (Sweden)

    Mariem Rouatbi

    2016-08-01

    Full Text Available This study aimed to investigate the effect of Haemonchus contortus infection on rams’ haematological, biochemical and clinical parameters and reproductive performances. A total number of 12 Barbarine rams (control and infected were included in the experiment. The infected group received 30 000 H. contortus third-stage larvae orally. Each ram’s ejaculate was immediately evaluated for volume, sperm cell concentration and mortality rate. At the end of the experiment (day 82 post-infection, which lasted 89 days, serial blood samples were collected in order to assess plasma testosterone and luteinising hormone (LH concentrations. There was an effect of time, infection and their interaction on haematological parameters (p < 0.001. In infected rams, haematocrit, red blood cell count and haemoglobin started to decrease from 21 days post-infection. There was an effect of time and infection for albumin. For total protein, only infection had a statistically significant effect. For glucose, only time had a statistically significant effect. Concentrations were significantly lower in infected rams compared to control animals. A significant effect of infection and time on sperm concentrations and sperm mortality was observed. The effect of infection appears in time for sperm concentrations at days 69 and 76 post-infection. Sperm mortality rate was significantly higher in infected animals at day 46 post-infection when compared to control group (p < 0.05. Finally, plasma testosterone traits (average concentration, cumulated levels during the sampling period and pulse frequency were depressed in infected rams when compared to control counterparts; none of these endocrine traits were affected for plasma LH.

  14. Important parameters in the performance of a potential repository at Yucca Mountain (TSPA-1995)

    International Nuclear Information System (INIS)

    Atkins, J.E.; Sevougian, S.D.; Lee, J.H.; Andrews, R.W.; McNeish, J.A.

    1996-01-01

    A total system performance assessment (TSPA) was conducted to determine how a potential repository at Yucca Mountain would behave. Using the results of this TSPA, regression was done to determine which parameters had the most important effect on the repository performance. These results were consistent with the current conceptual understanding of the repository

  15. Sensitivity Analysis of WEC Array Layout Parameters Effect on the Power Performance

    DEFF Research Database (Denmark)

    Ruiz, Pau Mercadé; Ferri, Francesco; Kofoed, Jens Peter

    2015-01-01

    This study assesses the effect that the array layout choice has on the power performance. To this end, a sensitivity analysis is carried out with six array layout parameters, as the simulation inputs, the array power performance (q-factor), as the simulation output, and a simulation model special...

  16. Performance emulation and parameter estimation for nonlinear fibre-optic links

    DEFF Research Database (Denmark)

    Piels, Molly; Porto da Silva, Edson; Zibar, Darko

    2016-01-01

    Fibre-optic communication systems, especially when operating in the nonlinear regime, generally do not perform exactly as theory would predict. A number of methods for data-based evaluation of nonlinear fibre-optic link parameters, both for accurate performance emulation and optimization...

  17. Working parameters affecting earth-air heat exchanger (EAHE) system performance for passive cooling: A review

    Science.gov (United States)

    Darius, D.; Misaran, M. S.; Rahman, Md. M.; Ismail, M. A.; Amaludin, A.

    2017-07-01

    The study on the effect of the working parameters such as pipe material, pipe length, pipe diameter, depth of burial of the pipe, air flow rate and different types of soils on the thermal performance of earth-air heat exchanger (EAHE) systems is very crucial to ensure that thermal comfort can be achieved. In the past decade, researchers have performed studies to develop numerical models for analysis of EAHE systems. Until recently, two-dimensional models replaced the numerical models in the 1990s and in recent times, more advanced analysis using three-dimensional models, specifically the Computational Fluid Dynamics (CFD) simulation in the analysis of EAHE system. This paper reviews previous models used to analyse the EAHE system and working parameters that affects the earth-air heat exchanger (EAHE) thermal performance as of February 2017. Recent findings on the parameters affecting EAHE performance are also presented and discussed. As a conclusion, with the advent of CFD methods, investigational work have geared up to modelling and simulation work as it saves time and cost. Comprehension of the EAHE working parameters and its effect on system performance is largely established. However, the study on type of soil and its characteristics on the performance of EAHEs systems are surprisingly barren. Therefore, future studies should focus on the effect of soil characteristics such as moisture content, density of soil, and type of soil on the thermal performance of EAHEs system.

  18. Determination of performance parameters of vertical axis wind turbines in wind tunnel

    Directory of Open Access Journals (Sweden)

    Nguyen Van Bang

    2017-01-01

    Full Text Available The paper deals with the determination of the performance parameters of a small vertical axis wind turbines (VAWT, which operate by the utilization of drag forces acting on the blades of the turbine. The performance was evaluated by investigating the electrical power output and torque moment of the wind machine. Measurements were performed on the full-scale model and the experimental data are assessed and compared to other types of wind turbines, with respect to its purpose.

  19. Human comfort and self-estimated performance in relation to indoor environmental parameters and building features

    OpenAIRE

    Frontczak, Monika Joanna; Wargocki, Pawel

    2011-01-01

    The main objective of the Ph.D. study was to examine occupants’ perception of comfort and self-estimated job performance in non-industrial buildings (homes and offices), in particular how building occupants understand comfort and which parameters, not necessarily related to indoor environments, influence the perception of comfort.To meet the objective, the following actions were taken: (1) a literature survey exploring which indoor environmental parameters (thermal, acoustic, visualenvironmen...

  20. Effects of the hydroethanolic extract of Mucuna pruriens (L.) DC (Fabaceae) on haematological profile in normal and haloperidol treated rats.

    Science.gov (United States)

    Akindele, Abidemi J; Busayo, Fadeyibi I

    2011-01-01

    Mucuna pruriens (L.) DC (Fabaceae) is a climbing plant claimed in traditional medicine to possess anti-anaemic effect. The study is to investigate the effects of the hydroethanolic extract of M. pruriens (MP) on haematological profile in normal and haloperidol treated rats. MP was administered p.o. at doses of 50, 100, 200, and 400 mg/kg to groups of rats daily for 28 days. Control animals received distilled water. Rats were sacrificed on the 28th day and blood samples collected for evaluation of haematological parameters and serum iron. Another set of animals received MP p.o. at same doses but along with haloperidol (0.2 mg/kg, i.p.) daily for 4 days. Three other groups of rats received distilled water, haloperidol, and MP at 400 mg/kg alone. Haematological parameters and serum iron were determined. Extract iron content, phytochemical analysis and acute toxicity studies were also carried out. MP administered to normal rats for 28 days significantly (p Mucuna pruriens possibly possess beneficial effects in anaemic conditions especially associated with iron deficiency.

  1. Availability of thermodynamic system with multiple performance parameters based on vector-universal generating function

    International Nuclear Information System (INIS)

    Cai Qi; Shang Yanlong; Chen Lisheng; Zhao Yuguang

    2013-01-01

    Vector-universal generating function was presented to analyze the availability of thermodynamic system with multiple performance parameters. Vector-universal generating function of component's performance was defined, the arithmetic model based on vector-universal generating function was derived for the thermodynamic system, and the calculation method was given for state probability of multi-state component. With the stochastic simulation of the degeneration trend of the multiple factors, the system availability with multiple performance parameters was obtained under composite factors. It is shown by an example that the results of the availability obtained by the binary availability analysis method are somewhat conservative, and the results considering parameter failure based on vector-universal generating function reflect the operation characteristics of the thermodynamic system better. (authors)

  2. Biological and haematological safety profile of oral amodiaquine ...

    African Journals Online (AJOL)

    Biological and haematological safety profile of oral amodiaquine and chloroquine in healthy volunteers with or without Plasmodium falciparum infection in northeast Tanzania. JJ Massaga, JP Lusingu, R Makunde, HM Malebo, MM Chile, JA Akida, MM Lemnge, AM Rønn, TG Theander, IC Bygbjerg, AY Kitua ...

  3. Thrombopoietin-receptor agonists in haematological disorders: The Danish experience

    DEFF Research Database (Denmark)

    Gudbrandsdottir, Sif; Frederiksen, Henrik; Hasselbalch, Hans

    2011-01-01

    The objective of this study was to investigate the use of thrombopoietin-receptor agonists (TPO-ra) in patients with refractory primary immune thrombocytopenia (ITP) as well as off-label use of TPO-ra in Danish haematology departments. Hospital medical records from 32 of the 39 patients having re...

  4. Haematology of infectious bursal disease virus infected chickens on ...

    African Journals Online (AJOL)

    Garlic (Allium sativum) is an herbal spice proven to posses antimicrobial and immunostimulating properties which could be useful in the control of endemic diseases of poultry such as infectious bursal disease (IBD). Its effect on IBD virus infection was therefore investigated via haematological assessment. One hundred and ...

  5. Some Biochemical and Haematological Studies on the Prevalence ...

    African Journals Online (AJOL)

    Dr J. T. Ekanem

    Printed in Nigeria. Some Biochemical and Haematological Studies on the Prevalence of Congenital Malaria in. Ilorin, Nigeria. Olatunji M. KOLAWOLE. 1 ... appropriate information filled such as maternal age, parity, past clinical history of malaria, anti malaria drug (such as chloroquine, amodiaquine in combination with.

  6. Escherichia coli bacteraemia in patients with and without haematological malignancies

    DEFF Research Database (Denmark)

    Olesen, B; Kolmos, H J; Orskov, F

    1998-01-01

    We compared serotypes, virulence factors and susceptibility to antibiotics of Escherichia coli strains isolated from 282 patients with bacteraemia. Thirty-five of these were neutropenic patients with haematological malignancy and 247 were patients with a normal or raised total white blood cell co...

  7. Genital tract morphometry and haematology of male rabbits fed ...

    African Journals Online (AJOL)

    Genital tract morphometry and haematology of male rabbits fed graded levels of cassava leaf meal. ... It was concluded that the inclusion of up to 27% of CLM in bucks' diets is not detrimental to good health and normal reproductive tract development. It is recommended that further studies on the feeding potentials of ...

  8. Haematology, serum biochemistry and organ weight changes of ...

    African Journals Online (AJOL)

    A total of fifty Wistar albino rats weighing 50-60g were randomly allocated to five dietary treatments in a completely randomized design to investigate the haematology, serum biochemistry and organ weight changes on diets containing processed dehulled jack bean. Four diets containing 10% crude protein were formulated ...

  9. diurnal climatic pressure on haematology and blood biochemistry of ...

    African Journals Online (AJOL)

    Twelve 2.5-year-old West African Dward (WAD) sheep consisting of eight (8) ewes and four (4) rams with mean body weight 19.4kg were used to study the effects of diurnal (morning and afternoon) climatic variations on the haematological and biochemical responses in WAD sheep. The animals were randomly assigned to ...

  10. Haematological and blood biochemical indices of West African ...

    African Journals Online (AJOL)

    Haematological and blood biochemical indices of West African dwarf goats vaccinated against Pestes des petit ruminants (PPR) ... blood biochemical indices of forty randomly selected West African dwarf (WAD) goats were studied. Packed cell volume ... neutrophil/lymphocyte ratio and white blood cells (WBC) than females.

  11. Haematological and Biochemical Indices of Growing Lambs Fed ...

    African Journals Online (AJOL)

    The experiment lasted for 84 days. Blood samples were collected prior to and after the feeding trial for haematological and blood urea nitrogen determination. Initial packed cell volume and final red blood cell counts were not significantly different between treatments (P>0.05). Initial haemoglobin concentration (HB) was

  12. Physiological and haematological indices of two Nigerian goat ...

    African Journals Online (AJOL)

    Introducing an indigenous or exotic breed to unfamiliar environment paves way for livestock improvement. This study examined the physiological and haematological indices of 24Red Sokoto (RS) and West African Dwarf (WAD) goats reared under uniform condition in Ilorin, to determine adaptability of RS goats over a ...

  13. Haematological and Serum Biochemical Variables in rats Treated ...

    African Journals Online (AJOL)

    The haematology and serum biochemical effects of oral administration of the ethanolic extract of the root of Moringa oleifera at 50, 100 and 150 mg/kg were investigated in 30 mated female Wistar rats. The rats were assigned into five groups of six rats each. Group A was given 50mg/kg of the extract; group B, 100mg/kg; ...

  14. The analgesic, haematological and some physiological effects of ...

    African Journals Online (AJOL)

    The aim of this research is to investigate the analgesic, haematologic and some physiological effects of extradural bupivacaine on dogs using six clinically healthy adult male dogs. The method used is by obtaining baseline data for physiological variables from each dogs using the multiparameter patient monitors (GD3, ...

  15. Haematological and hepatic indices of cockerels fed treated dietary ...

    African Journals Online (AJOL)

    Ninety-six day old Lairier cockerel chicks were used in an experiment to evaluate the after effects of detoxifying (soaking, boiling, addition of riboflavin and glycine to antagonize hypoglycins) dietary Blighia sapida (ackee apple) seed meal, BSSM. Blood chemistry, haematology, liver morphology indices which dietary BSSM ...

  16. Haematological and biochemical values of 10 green iguanas (Iguana iguana).

    Science.gov (United States)

    Divers, S J; Redmayne, G; Aves, E K

    1996-03-02

    Ten clinically healthy green iguanas (Iguana iguana) imported from South America were examined, and haematological and biochemical measurements were made on samples of blood. This paper describes the methods of blood sampling, handling and laboratory analysis, and presents the results as a set of normal blood ranges for the green iguana.

  17. Haematology and serum chemistry of finisher broiler chickens fed ...

    African Journals Online (AJOL)

    This study was conducted to assess the haematology and serum chemistry of broiler chickens fed maize-cassava diets supplemented with methionine and inorganic sulphur. A total of 270 day-old broiler chicks were randomly assigned to nine treatment groups of 30 birds making 10 birds per replicate group. Starter and ...

  18. Normal Haematological Values Of Nigerian Students As Seen In ...

    African Journals Online (AJOL)

    Objective: To determine the normal haematological values of secondary school students. Age range 11 – 22 years. Design: Venous blood samples were collected from students of three secondary schools at Anambra State. Settings: The samples were collected with sterile syringes and needles into haeparinized bottles and ...

  19. Haematological changes in the blood of cultured Clarias gariepinus ...

    African Journals Online (AJOL)

    This study investigated the artifactual changes in the haematological values of Clarias gariepinus blood stored at room (32oC) and refrigerator (4oC) temperatures. Blood samples were collected from 12 apparently healthy fish weighing between 0.8 and 1kg. Samples were divided into two parts immediately after collection ...

  20. Haematological profile and serum biochemical indices of weaned ...

    African Journals Online (AJOL)

    This study was carried out to determine the haematological profile and serum biochemical indices of rabbits fed pawpaw (Carica papaya) leaves as feed supplement to a corn – soybean mealbasal diet. The study involved thirty six (36) cross bred (New Zealand White X Chinchilla) mixed sex weaned rabbits of five - six ...

  1. Effect of organic contrast Media on the haematology and Serum ...

    African Journals Online (AJOL)

    Key Words: Contrast media, haematology, serum electrolytes, dogs, xylazine. The effect of contrast media on the hematology and serum electrolyte was determined in five dogs sedated with 2mg/kg of xylazine intramuscular (i.m). A total of 800mg/kg bolus of 76% urograffin was then administered by intravenous injection ...

  2. The influence of sex on the haematological values of apparently ...

    African Journals Online (AJOL)

    Blood samples were collected from fifty apparently healthy adult Sahel goats, twenty five each of male and female in Maiduguri to assess the influence of sex on their haematology. The red blood cell (RBC) counts, white blood cell (WBC) counts, haemoglobin (Hb) concentration, packed cell volume (PCV), platelet counts, ...

  3. Effect on some haematological indices of human whole blood when ...

    African Journals Online (AJOL)

    DR UGHACHUKWU

    2013-07-31

    Jul 31, 2013 ... Ughachukwu, P. O.1*, Ezenyeaku, C. C. T.2, Onwurah, W. O.3, Ifediata, F. E.3, ... 4Department of Pharmacology and Therapeutics, College of Health Sciences, Nnamdi Azikiwe ... PCV, MCV, MCH and MCHC using haematology autoanalyser (Erma Inc, PCE - 210). ..... Saponins in Food, Foodstuffs and.

  4. The Place of Splenectomy in Haematological Disorders | Gale ...

    African Journals Online (AJOL)

    The results of 67 consecutive splenectomies carried out in patients attending the Haematology Clinic at the Johannesburg Hospital between 1965 and 1972 are reported. Forty patients underwent splenectomy because of the presence of cytopenia due in part at least to hypersplenism. The best results were achieved in 21 ...

  5. Curriculum Design of a Flipped Classroom to Enhance Haematology Learning

    Science.gov (United States)

    Porcaro, Pauline A.; Jackson, Denise E.; McLaughlin, Patricia M.; O'Malley, Cindy J.

    2016-01-01

    A common trend in higher education is the "flipped" classroom, which facilitates active learning during class. The flipped approach to teaching was instituted in a haematology "major" class and the students' attitudes and preferences for the teaching materials were surveyed. The curriculum design was explicit and involved four…

  6. Oral and intramuscular application of cyanogenic glycoside amygdalin did not induce changes in haematological profile of male rabbits

    Directory of Open Access Journals (Sweden)

    Katarína Zbyňovská

    2017-01-01

    Full Text Available Amygdalin is a cyanogenic glycoside initially obtained from the seeds of bitter almonds. It is composed of one molecule of benzaldehyde, two molecules of glucose and one molecule of hydrocyanic acid. Various ways of amygdalin application play a different role in recipient organism. Intravenous infusion of amygdalin produced neither cyanidemia nor signs of toxicity, but oral administration resulted in significant blood cyanide levels. The present in vivo study was designed to reveal whether amygdalin is able to cause changes in the haematological profile and thus alter the physiological functions, using rabbits as a biological model. Adult male rabbits (n = 20 were randomly divided into five groups: the control group without any amygdalin administration, two experimental groups received a daily intramuscular injection of amygdalin at a dose 0.6 and 3.0 mg.kg-1 b.w. and other two groups were fed by crushed apricot seeds at dose 60 and 300 mg. kg-1 b.w., mixed with commercial feed over the period of 14 days. After two weeks, haematological parameters in whole blood were analysed (WBC - total white blood cell count, LYM - lymphocytes count, MID - medium size cell count, GRA - granulocytes count, RBC - red blood cell count, HGB - haemoglobin, HCT - haematocrit, MCV - mean corpuscular volume, MCH - mean corpuscular hemoglobin, MCHC - mean corpuscular hemoglobin concentration, RDWc - red cell distribution width, PLT - platelet count, PCT - platelet percentage, MPV - mean platelet volume, PDWc - platelet distribution width using haematology analyser Abacus junior VET. Our findings indicate that intramuscular and oral application of amygdalin for two weeks did not significantly affect the haematology parameters in experimental animals. In this study, no obvious beneficial or negative effects of amygdalin administration on the blood of male rabbits were observed.

  7. Evaluation of cyclone geometry and its influence on performance parameters by computational fluid dynamics (CFD

    Directory of Open Access Journals (Sweden)

    W. P. Martignoni

    2007-03-01

    Full Text Available Cyclone models have been used without relevant modifications for more than a century. Most of the attention has been focused on finding new methods to improve performance parameters. Recently, some studies were conducted to improve equipment performance by evaluating geometric effects on projects. In this work, the effect of cyclone geometry was studied through the creation of a symmetrical inlet and a volute scroll outlet section in an experimental cyclone and comparison to an ordinary single tangential inlet. The study was performed for gas-solid flow, based on an experimental study available in the literature, where a conventional cyclone model was used. Numerical experiments were performed by using CFX 5.7.1. The axial and tangential velocity components were evaluated using RSM and LES turbulence models. Results showed that these new designs can improve the cyclone performance parameters significantly and very interesting details were found on cyclone fluid dynamics properties using RSM and LES.

  8. ZYGOMYCOSIS IN IMMUNOCOMPROMISED NON-HAEMATOLOGICAL PATIENTS

    Directory of Open Access Journals (Sweden)

    George Petrikkos

    2011-01-01

    Full Text Available

    Zygomycoses are rare emerging diseases with a high fatality rate.  The most important risk factors include neutropenia or functional neutropenia, diabetic ketoacidosis, iron overload, major trauma, prolonged use of corticosteroids, illicit intravenous drug use, neonatal prematurity, malnourishment, and pre-exposure to antifungal agents with no activity against zygomycetes, such as voriconazole and caspofungin.

    A high index of suspicion is crucial for the diagnosis, as prompt and appropriate management can considerably reduce morbidity and mortality. Suspicion index can be increased through recognition of the differential patterns of clinical presentation. In the non- haematological immunocompromised patients, zygomycosis can manifest in various clinical forms, depending on the underlying condition: mostly as rhino-orbital or rhino-cerebral in diabetes patients, pulmonary infection in patients with malignancy or solid organ transplantation, disseminated infection in iron overloaded or deferoxamine

  9. Blood composition of the reindeer. I. Haematology

    Directory of Open Access Journals (Sweden)

    Mauri Nieminen

    1981-05-01

    Full Text Available The semi-domestic reindeer is a ruminant which exhibits a highly advanced adaptation to the marked seasonality of the northern environment. Since the reindeer has an economic importance and previous information about its blood composition is scanty in respect to age, season, calving and nutrition, the haematology of 578 reindeer were studied. The blood samples were taken from the jugular vein mainly in connection with the marking of calves during summer and at reindeer round-ups in autumn and winter at 10 reindeer rearing subunits in Northern Finland in various seasons in 1973-79. The red blood cell count (8xl012/l, haemoglobin (108 g/1, packed cell volume (35%, white blood cell count (6x109/l and serum iron (26 micromol/1 were low in newborn calves and reached their adult levels in autumn at the age of 5 months (average 11 x 1012/1, 182 g/1, 51%, 9x109/l, 44 micromol/1, respectively. The total serum bilirubin was relatively stable and vitamin B12 high in the first days after birth. The stable serum bilirubin indicates a relatively small breakdown of foetal erythrocytes. E-MCV of adult females was about 49 fl and the diameter of round erythrocytes about 5.5 microm and their thickness about 1.5 microm. No sickling was observed. The red cell osmotic fragility had a initial and final haemolysis points of 0.71 and 0.37% NaCl solution. The relative proportions of neutrophil, eosinophil and basophil granulocytes and agranular lymphocytes and monocytes were 52, 5, 2, 42 and 2 %, respectively. The calving of the reindeer occurs without visible haemorrhage. The body weight, red blood cell count, haemoglobin, packed cell volume and serum iron of pregnant hinds dropped, however, during the early lactation period, and a relative anaemia developed is partly due to iron deficiency and, perhaps, also breakdown of foetal erythrocytes. The means of body weight (range 50-70 kg, red blood cell count (8-11 x 1012/l, haemoglobin (118-185 g/1, packed cell volume (42

  10. ROLE OF BONE MARROW ASPIRATION IN DIAGNOSIS OF HAEMATOLOGICAL DISORDER

    Directory of Open Access Journals (Sweden)

    Poonam Nanwani

    2017-03-01

    Full Text Available BACKGROUND The bone marrow examination is an essential investigation for the diagnosis of disorders of the blood and bone marrow. This simple and relatively safe procedure is important, particularly in resource poor centres since access to adjuvant diagnostic techniques are often lacking or absent. MATERIALS AND METHODS 189 patients of all age groups were studied for haematological and non-haematological disorders by bone marrow aspiration in the Department of Pathology, MGM Medical College during the period of 2014 to 2016. RESULTS Majority of the patients who had bone marrow aspiration were aged 0-15 years. The male-to-female ratio was 1:1.03. Most (97% of the marrow aspirate examined had definitive pathologic features, while 14 (7% were normal marrow elements. Out of 189 cases of bone marrow aspiration, acute leukaemia was the most common haematological disease diagnosed using this procedure. Acute lymphoblastic leukaemia was more common than acute myeloid leukaemia. Aplastic anaemia was seen in 16% cases. Megaloblastic anaemia occurred more commonly than other anaemias. Megaloblastic anaemia was seen in 13 cases (7% and microcytic anaemia was seen in 5 cases (3%. There were 10 cases (5% of Idiopathic Thrombocypenic Purpura. Myelodysplastic syndrome and multiple myeloma was seen in 7% and 2% cases respectively. Storage disorder was seen in 3 cases (2%, out of this 02 cases were Gaucher’s disease and one case was Niemann-Pick’s disease. CONCLUSION Bone marrow examination is an important step to arrive at the confirmatory diagnosis of many haematological disorders. This procedure remains a veritable tool in the diagnosis and management of a wide range of haematological diseases, especially in a resource poor centre.

  11. phytochemistry and some haematological changes following oral ...

    African Journals Online (AJOL)

    Daniel Owu

    constituents and effect of ethanolic root extract of Gonglonema latifolium on some hematological parameters. ... saponins. (asterglycosides), alkaloids, minerals like calcium, phosphorus, magnesium ... out using standard laboratory techniques.

  12. An Efficient Data Partitioning to Improve Classification Performance While Keeping Parameters Interpretable.

    Directory of Open Access Journals (Sweden)

    Kristjan Korjus

    Full Text Available Supervised machine learning methods typically require splitting data into multiple chunks for training, validating, and finally testing classifiers. For finding the best parameters of a classifier, training and validation are usually carried out with cross-validation. This is followed by application of the classifier with optimized parameters to a separate test set for estimating the classifier's generalization performance. With limited data, this separation of test data creates a difficult trade-off between having more statistical power in estimating generalization performance versus choosing better parameters and fitting a better model. We propose a novel approach that we term "Cross-validation and cross-testing" improving this trade-off by re-using test data without biasing classifier performance. The novel approach is validated using simulated data and electrophysiological recordings in humans and rodents. The results demonstrate that the approach has a higher probability of discovering significant results than the standard approach of cross-validation and testing, while maintaining the nominal alpha level. In contrast to nested cross-validation, which is maximally efficient in re-using data, the proposed approach additionally maintains the interpretability of individual parameters. Taken together, we suggest an addition to currently used machine learning approaches which may be particularly useful in cases where model weights do not require interpretation, but parameters do.

  13. Computer simulation for prediction of performance and thermodynamic parameters of high energy materials

    International Nuclear Information System (INIS)

    Muthurajan, H.; Sivabalan, R.; Talawar, M.B.; Asthana, S.N.

    2004-01-01

    A new code viz., Linear Output Thermodynamic User-friendly Software for Energetic Systems (LOTUSES) developed during this work predicts the theoretical performance parameters such as density, detonation factor, velocity of detonation, detonation pressure and thermodynamic properties such as heat of detonation, heat of explosion, volume of explosion gaseous products. The same code also assists in the prediction of possible explosive decomposition products after explosion and power index. The developed code has been validated by calculating the parameters of standard explosives such as TNT, PETN, RDX, and HMX. Theoretically predicated parameters are accurate to the order of ±5% deviation. To the best of our knowledge, no such code is reported in literature which can predict a wide range of characteristics of known/unknown explosives with minimum input parameters. The code can be used to obtain thermochemical and performance parameters of high energy materials (HEMs) with reasonable accuracy. The code has been developed in Visual Basic having enhanced windows environment, and thereby advantages over the conventional codes, written in Fortran. The theoretically predicted HEMs performance can be directly printed as well as stored in text (.txt) or HTML (.htm) or Microsoft Word (.doc) or Adobe Acrobat (.pdf) format in the hard disk. The output can also be copied into the Random Access Memory as clipboard text which can be imported/pasted in other software as in the case of other codes

  14. Development of multiple performance indices and system parameter study for the design of a MEMS accelerometer

    International Nuclear Information System (INIS)

    Kim, Yong Il; Choi, Chan Kyu; Yoo, Hong Hee

    2012-01-01

    For the design of a MEMS accelerometer, proper performance indices should be defined and employed. Performance indices are obtained using either an experimental method or a numerical method. In the present study, a vibration analysis model of a MEMS accelerometer is introduced to calculate three performance indices: sensitivity, measurable acceleration range, and measurable frequency range. The accuracy of the vibration analysis model is first validated by comparing its modal and transient results with those of a commercial finite element code. Measurable acceleration and frequency ranges versus allowable errors for electrical and mechanical sensitivities are obtained and the effects of system parameter variations on the three performance indices are investigated

  15. The player and the bowed string: coordination of bowing parameters in violin and viola performance.

    Science.gov (United States)

    Schoonderwaldt, E

    2009-11-01

    An experiment was conducted with four violin and viola players, measuring their bowing performance using an optical motion capture system and sensors on the bow. The measurements allowed for a detailed analysis of the use and coordination of the main bowing parameters bow velocity, bow force, and bow-bridge distance. An analysis of bowing strategies in detache playing of notes of three durations (0.2, 2, and 4 s) at three dynamic levels (pp, mf, and f) on all four strings is presented, focusing on the "steady" part of the notes. The results revealed clear trends in the coordinated variations of the bowing parameters depending on the constraints of the task, reflecting a common behavior as well as individual strategies. Furthermore, there were clear indications that the players adapted the bowing parameters to the physical properties of the string and the instrument, respecting the limits of the playable control parameter space.

  16. The need for control of magnetic parameters for energy efficient performance of magnetic tunnel junctions

    Science.gov (United States)

    Farhat, I. A. H.; Gale, E.; Alpha, C.; Isakovic, A. F.

    2017-07-01

    Optimizing energy performance of Magnetic Tunnel Junctions (MTJs) is the key for embedding Spin Transfer Torque-Random Access Memory (STT-RAM) in low power circuits. Due to the complex interdependencies of the parameters and variables of the device operating energy, it is important to analyse parameters with most effective control of MTJ power. The impact of threshold current density, Jco , on the energy and the impact of HK on Jco are studied analytically, following the expressions that stem from Landau-Lifshitz-Gilbert-Slonczewski (LLGS-STT) model. In addition, the impact of other magnetic material parameters, such as Ms , and geometric parameters such as tfree and λ is discussed. Device modelling study was conducted to analyse the impact at the circuit level. Nano-magnetism simulation based on NMAGTM package was conducted to analyse the impact of controlling HK on the switching dynamics of the film.

  17. Effect of fuel fabrication parameters on performance- designer's point of view

    International Nuclear Information System (INIS)

    Prasad, P.N.; Ravi, M.; Soni, R.; Bajaj, S.S.; Bhardwaj, S.A.

    2004-01-01

    The fuel bundle performance in reactor depends upon the material properties, dimensions of the different components and their inter-compatibility. This paper brings out the fuel parameters required to be optimised to achieve better fuel reliability, operational flexibility, safety and economics from the designer point of view

  18. Satisfaction and self-estimated performance in relation to indoor environmental parameters and building features

    DEFF Research Database (Denmark)

    Wargocki, Pawel; Frontczak, Monika; Schiavon, Stefano

    2012-01-01

    The paper examines how satisfaction with indoor environmental parameters and building features affects satisfaction and self-estimated job performance. The analyses used subjective responses from around 50, 000 occupants collected mainly in US office buildings using a web-based survey administered...

  19. HAEMATOLOGICAL PROFILE FOLLOWING IMMUNOMODULATION DURING LATE GESTATION IN BUFFALOES (BUBALIS BUBALUS

    Directory of Open Access Journals (Sweden)

    Z.I, Qureshi, L.A. Lodhi, H.A. Samad, N.A. Naz1 and M. Nawaz

    2001-07-01

    Full Text Available Thirty-two adult riverine buffaloes (Buhalis bubalus in their last trimester of pregnancy were selected and randomly divided into four groups. The buffaloes of group I served as control. Animals in group II, III and IV were treated twice (7 days apart with levamisole hydrochloride (0.5mg/kg b. w. orally, Etosol (Vit E+Se, 10ml, I/m and Bacilli Calmette Guerine (BCG (0.5 ml/animal, s/c, respectively. Blood samples were collected at weekly intervals starting day 0 untill parturition. Total erythrocytic count and packed cell volume values were higher (P<0.05 in levamisole and vit E+Se treated group of buffaloes. Haemoglobin concentration was higher (P<0.05 inVit E+Se treated group. MCV, MCH and MCHC remained unchanged among all the experimental groups. Total leukocyte count was higher (P<0.05 in levamisole treated group of buffaloes. Differential leukocyte counts (relative revealed moderate lymphocytosis in all immunomodulated groups with significantly higher counts in Vit E+Se treated buffaloes. It was inferred that levamisole and vit E-se altered some haematological values, whereas BCG did not affect the haematological parameters.

  20. Effect of calibration data series length on performance and optimal parameters of hydrological model

    Directory of Open Access Journals (Sweden)

    Chuan-zhe Li

    2010-12-01

    Full Text Available In order to assess the effects of calibration data series length on the performance and optimal parameter values of a hydrological model in ungauged or data-limited catchments (data are non-continuous and fragmental in some catchments, we used non-continuous calibration periods for more independent streamflow data for SIMHYD (simple hydrology model calibration. Nash-Sutcliffe efficiency and percentage water balance error were used as performance measures. The particle swarm optimization (PSO method was used to calibrate the rainfall-runoff models. Different lengths of data series ranging from one year to ten years, randomly sampled, were used to study the impact of calibration data series length. Fifty-five relatively unimpaired catchments located all over Australia with daily precipitation, potential evapotranspiration, and streamflow data were tested to obtain more general conclusions. The results show that longer calibration data series do not necessarily result in better model performance. In general, eight years of data are sufficient to obtain steady estimates of model performance and parameters for the SIMHYD model. It is also shown that most humid catchments require fewer calibration data to obtain a good performance and stable parameter values. The model performs better in humid and semi-humid catchments than in arid catchments. Our results may have useful and interesting implications for the efficiency of using limited observation data for hydrological model calibration in different climates.

  1. Thermal performance parameters estimation of hot box type solar cooker by using artificial neural network

    Energy Technology Data Exchange (ETDEWEB)

    Kurt, Hueseyin; Atik, Kemal; Oezkaymak, Mehmet; Recebli, Ziyaddin [Zonguldak Karaelmas University, Karabuk Technical Education Faculty, 78200 Karabuk (Turkey)

    2008-02-15

    Work to date has shown that Artificial Neural Network (ANN) has not been used for predicting thermal performance parameters of a solar cooker. The objective of this study is to predict thermal performance parameters such as absorber plate, enclosure air and pot water temperatures of the experimentally investigated box type solar cooker by using the ANN. Data set is obtained from the box type solar cooker which was tested under various experimental conditions. A feed-forward neural network based on back propagation algorithm was developed to predict the thermal performance of solar cooker with and without reflector. Mathematical formulations derived from the ANN model are presented for each predicting temperatures. The experimental data set consists of 126 values. These were divided into two groups, of which the 96 values were used for training/learning of the network and the rest of the data (30 values) for testing/validation of the network performance. The performance of the ANN predictions was evaluated by comparing the prediction results with the experimental results. The results showed a good regression analysis with the correlation coefficients in the range of 0.9950-0.9987 and mean relative errors (MREs) in the range of 3.925-7.040% for the test data set. The regression coefficients indicated that the ANN model can successfully be used for the prediction of the thermal performance parameters of a box type solar cooker with a high degree of accuracy. (author)

  2. Screening key parameters related to passive system performance based on Analytic Hierarchy Process

    International Nuclear Information System (INIS)

    Ma, Guohang; Yu, Yu; Huang, Xiong; Peng, Yuan; Ma, Nan; Shan, Zuhua; Niu, Fenglei; Wang, Shengfei

    2015-01-01

    Highlights: • An improved AHP method is presented for screening key parameters used in passive system reliability analysis. • We take the special bottom parameters as criterion for calculation and the abrupt change of the results are verified. • Combination weights are also affected by uncertainty of input parameters. - Abstract: Passive safety system is widely used in the new generation nuclear power plant (NPP) designs such as AP1000 to improve the reactor safety benefitting from its simple construction and less request for human intervene. However, the functional failure induced by uncertainty in the system thermal–hydraulic (T–H) performance becomes one of the main contributors to system operational failure since the system operates based on natural circulation, which should be considered in the system reliability evaluation. In order to improve the calculation efficiency the key parameters which significantly affect the system T–H characteristics can be screened and then be analyzed in detail. The Analytical Hierarchy Process (AHP) is one of the efficient methods to analyze the influence of the parameters on a passive system based on the experts’ experience. The passive containment cooling system (PCCS) in AP1000 is one of the typical passive safety systems, nevertheless too many parameters need to be analyzed and the T–H model itself is more complicated, so the traditional AHP method should be mended to use for screening key parameters efficiently. In this paper, we adapt the improved method in hierarchy construction and experts’ opinions integration, some parameters at the bottom justly in the traditional hierarchy are studied as criterion layer in improved AHP, the rationality of the method and the effect of abrupt change with the data are verified. The passive containment cooling system (PCCS) in AP1000 is evaluated as an example, and four key parameters are selected from 49 inputs

  3. Effect of adding crushed Pimpinella anisum, Nigella sativa seeds and Thymus vulgaris mixture to antibiotics-free rations of vaccinated and non-vaccinated male broilers on growth performance, antibody titer and haematological profile

    Directory of Open Access Journals (Sweden)

    Mamoun Z. Athamneh

    2010-04-01

    Full Text Available This research explores an experimental study conducted to investigate the effect of crushed Pimpinella anisum (PA, Nigella sativa (NS seeds and Thymus vulgaris (TV mixture as a feed additive on growth performance and mortality rate (MR, selected antibodies titer (Ab’s and blood hematological profile of vaccinated and non-vaccinated Lohman male broiler chicks fed free-antibiotics ration. A total of 400 one-day old chicks were distributed into 16 groups (4 treatment x 4 replicates x 25chicks. The experiment lasted from one to 42 days of age. The statistical findings of this experiment prove that the use of medicinal plants mixture improves live body weight, body weight gain, feed conversion ratio and MR of vaccinated male broilers at 21 and 42 days of age. antibodies titer against infectious bronchitis and infectious bursal disease of non-vaccinated and vaccinated male broilers were significantly improved at 21 and 42 days as a result of the addition of medicinal plant mixture to the basal ration. Concerning Newcastle disease, the use of PA, NS and TV mixture did not reflect in any additional improvement of Ab's than vaccines did. The addition of medicinal plants mixture increases WBC's, RBC's, thrombocytes count and Hb concentration of vaccinated and non-vaccinated male broilers at 21 days of age. Meanwhile, heterophils, lymphocytes and monocytes of vaccinated male broilers (VMB were significantly improved by adding medicinal plant mixture to their basal diet. Moreover, at 42 days of age the use of PA, NS seeds and TV mixture indicate significant increase in total WBC’s, lymphocytes and monocytes and monocytes count of VMB and non-vaccinated male broiler (NVMB. No significant differences were noticed in RBC’s and Hct as a result of feeding crushed medicinal plants mixture.

  4. Identification of the contribution of contact and aerial biomechanical parameters in acrobatic performance.

    Directory of Open Access Journals (Sweden)

    Diane Haering

    Full Text Available Teaching acrobatic skills with a minimal amount of repetition is a major challenge for coaches. Biomechanical, statistical or computer simulation tools can help them identify the most determinant factors of performance. Release parameters, change in moment of inertia and segmental momentum transfers were identified in the prediction of acrobatics success. The purpose of the present study was to evaluate the relative contribution of these parameters in performance throughout expertise or optimisation based improvements. The counter movement forward in flight (CMFIF was chosen for its intrinsic dichotomy between the accessibility of its attempt and complexity of its mastery.Three repetitions of the CMFIF performed by eight novice and eight advanced female gymnasts were recorded using a motion capture system. Optimal aerial techniques that maximise rotation potential at regrasp were also computed. A 14-segment-multibody-model defined through the Rigid Body Dynamics Library was used to compute recorded and optimal kinematics, and biomechanical parameters. A stepwise multiple linear regression was used to determine the relative contribution of these parameters in novice recorded, novice optimised, advanced recorded and advanced optimised trials. Finally, fixed effects of expertise and optimisation were tested through a mixed-effects analysis.Variation in release state only contributed to performances in novice recorded trials. Moment of inertia contribution to performance increased from novice recorded, to novice optimised, advanced recorded, and advanced optimised trials. Contribution to performance of momentum transfer to the trunk during the flight prevailed in all recorded trials. Although optimisation decreased transfer contribution, momentum transfer to the arms appeared.Findings suggest that novices should be coached on both contact and aerial technique. Inversely, mainly improved aerial technique helped advanced gymnasts increase their

  5. Blood gases, biochemistry and haematology of Galápagos marine iguanas (Amblyrhynchus cristatus)

    Science.gov (United States)

    Lewbart, Gregory A.; Hirschfeld, Maximilian; Brothers, J. Roger; Muñoz-Pérez, Juan Pablo; Denkinger, Judith; Vinueza, Luis; García, Juan; Lohmann, Kenneth J.

    2015-01-01

    The marine iguana, Amblyrhynchus cristatus, is an iconic lizard endemic to the Galápagos Islands of Ecuador, but surprisingly little information exists on baseline health parameters for this species. We analysed blood samples drawn from 35 marine iguanas captured at three locations on San Cristóbal Island. A portable blood analyser (iSTAT) was used to obtain near-immediate field results for pH, lactate, partial pressure of O2, partial pressure of CO2, bicarbonate (HCO3−), percentage O2 saturation, haematocrit, haemoglobin, sodium, potassium, ionized calcium and glucose. Parameter values affected by temperature were auto-corrected by the iSTAT. Standard laboratory haematology techniques were employed for differential white blood cell counts and haematocrit determination; resulting values were also compared with the haematocrit values generated by the iSTAT. Body temperature, heart rate, respiratory rate and body measurements were also recorded. Body length was positively correlated with several blood chemistry values (HCO3− and glucose) and two haematology parameters (haemoglobin and manually determined haematocrit). A notable finding was the unusually high blood sodium level; the mean value of 178 mg/dl is among the highest known for any reptile. This value is likely to be a conservative estimate because some samples exceeded the maximal value the iSTAT can detect. For haematocrit determination, the iSTAT blood analyser yielded results significantly lower than those obtained with high-speed centrifugation. The values reported in this study provide baseline data that may be useful in comparisons among populations and in detecting changes in health status among marine iguanas affected by natural disturbances or anthropogenic threats. The findings might also be helpful in future efforts to demonstrate associations between specific biochemical parameters and disease. PMID:27293719

  6. Blood gases, biochemistry and haematology of Galápagos marine iguanas (Amblyrhynchus cristatus).

    Science.gov (United States)

    Lewbart, Gregory A; Hirschfeld, Maximilian; Brothers, J Roger; Muñoz-Pérez, Juan Pablo; Denkinger, Judith; Vinueza, Luis; García, Juan; Lohmann, Kenneth J

    2015-01-01

    The marine iguana, Amblyrhynchus cristatus, is an iconic lizard endemic to the Galápagos Islands of Ecuador, but surprisingly little information exists on baseline health parameters for this species. We analysed blood samples drawn from 35 marine iguanas captured at three locations on San Cristóbal Island. A portable blood analyser (iSTAT) was used to obtain near-immediate field results for pH, lactate, partial pressure of O2, partial pressure of CO2, bicarbonate (HCO3 (-)), percentage O2 saturation, haematocrit, haemoglobin, sodium, potassium, ionized calcium and glucose. Parameter values affected by temperature were auto-corrected by the iSTAT. Standard laboratory haematology techniques were employed for differential white blood cell counts and haematocrit determination; resulting values were also compared with the haematocrit values generated by the iSTAT. Body temperature, heart rate, respiratory rate and body measurements were also recorded. Body length was positively correlated with several blood chemistry values (HCO3 (-) and glucose) and two haematology parameters (haemoglobin and manually determined haematocrit). A notable finding was the unusually high blood sodium level; the mean value of 178 mg/dl is among the highest known for any reptile. This value is likely to be a conservative estimate because some samples exceeded the maximal value the iSTAT can detect. For haematocrit determination, the iSTAT blood analyser yielded results significantly lower than those obtained with high-speed centrifugation. The values reported in this study provide baseline data that may be useful in comparisons among populations and in detecting changes in health status among marine iguanas affected by natural disturbances or anthropogenic threats. The findings might also be helpful in future efforts to demonstrate associations between specific biochemical parameters and disease.

  7. Key parameters of the swimming start and their relationship to start performance.

    Science.gov (United States)

    Tor, Elaine; Pease, David L; Ball, Kevin A

    2015-01-01

    The swimming start is typically broken into three sub-phases; on-block, flight, and underwater phases. While overall start performance is highly important to elite swimming, the contribution of each phase and important technical components within each phase, particularly with the new kick-start technique, has not been established. The aim of this study was to identify technical factors associated with overall start performance, with a particular focus on the underwater phase. A number of parameters were calculated from 52 starts performed by elite freestyle and butterfly swimmers. These parameters were split into above-water and underwater groupings, before factor analysis was used to reduce parameter numbers for multiple regression. For the above-water phases, 81% of variance in start performance was accounted for by take-off horizontal velocity. For the underwater water phase, 96% of variance was accounted for with time underwater in descent, time underwater in ascent and time to 10 m. Therefore, developing greater take-off horizontal velocity and focussing on the underwater phase by finding the ideal trajectory will lead to improved start performance.

  8. Parameter Selection and Performance Comparison of Particle Swarm Optimization in Sensor Networks Localization

    Directory of Open Access Journals (Sweden)

    Huanqing Cui

    2017-03-01

    Full Text Available Localization is a key technology in wireless sensor networks. Faced with the challenges of the sensors’ memory, computational constraints, and limited energy, particle swarm optimization has been widely applied in the localization of wireless sensor networks, demonstrating better performance than other optimization methods. In particle swarm optimization-based localization algorithms, the variants and parameters should be chosen elaborately to achieve the best performance. However, there is a lack of guidance on how to choose these variants and parameters. Further, there is no comprehensive performance comparison among particle swarm optimization algorithms. The main contribution of this paper is three-fold. First, it surveys the popular particle swarm optimization variants and particle swarm optimization-based localization algorithms for wireless sensor networks. Secondly, it presents parameter selection of nine particle swarm optimization variants and six types of swarm topologies by extensive simulations. Thirdly, it comprehensively compares the performance of these algorithms. The results show that the particle swarm optimization with constriction coefficient using ring topology outperforms other variants and swarm topologies, and it performs better than the second-order cone programming algorithm.

  9. Parameter Selection and Performance Comparison of Particle Swarm Optimization in Sensor Networks Localization.

    Science.gov (United States)

    Cui, Huanqing; Shu, Minglei; Song, Min; Wang, Yinglong

    2017-03-01

    Localization is a key technology in wireless sensor networks. Faced with the challenges of the sensors' memory, computational constraints, and limited energy, particle swarm optimization has been widely applied in the localization of wireless sensor networks, demonstrating better performance than other optimization methods. In particle swarm optimization-based localization algorithms, the variants and parameters should be chosen elaborately to achieve the best performance. However, there is a lack of guidance on how to choose these variants and parameters. Further, there is no comprehensive performance comparison among particle swarm optimization algorithms. The main contribution of this paper is three-fold. First, it surveys the popular particle swarm optimization variants and particle swarm optimization-based localization algorithms for wireless sensor networks. Secondly, it presents parameter selection of nine particle swarm optimization variants and six types of swarm topologies by extensive simulations. Thirdly, it comprehensively compares the performance of these algorithms. The results show that the particle swarm optimization with constriction coefficient using ring topology outperforms other variants and swarm topologies, and it performs better than the second-order cone programming algorithm.

  10. Comparative analysis of partial imaging performance parameters of home and imported X-ray machines

    International Nuclear Information System (INIS)

    Cao Yunxi; Wang Xianyun; Liu Huiqin; Guo Yongxin

    2002-01-01

    Objective: To compare and analyze the performance indexes and the imaging quality of the home and imported X-ray machines through testing their partial imaging performance parameters. Methods: By separate sampling from 10 home and 10 imported X-ray machines, the parameters including tube current, time of exposure, machine total exposure, and repeatability were tested, and the imaging performance was evaluated according to the national standard. Results: All the performance indexes met the standard of GB4505-84. The first sampling tests showed the maximum changing coefficient of imaging performance repeatability of the home X-ray machines was Δmax1 = 0.025, while that of the imported X-ray machine was Δmax1 = 0.016. In the second sampling tests, the maximum changing coefficients of the two were Δmax2 = 0.048 and Δmax2 = 0.022, respectively. Conclusion: The 2 years' follow-up tests indicate that there is no significant difference between the above-mentioned parameters of the elaborately adjusted home X-ray machines and imported ones, but the home X-ray machines are no better than the imported X-ray machines in stability and consistency

  11. Characteristics of bone marrow with dynamic contrast-enhanced MR imaging in patients with haematological malignancies: preliminary results

    International Nuclear Information System (INIS)

    Zhang Lei; Yang Zhenyan; Pitman, A.G.

    2007-01-01

    Objective: To determine whether dynamic contrast-enhanced MR (DCE-MRI) can successfully predict the status of diffusely abnormal bone marrow, and so obviate some bone marrow biopsies done for this indication. Methods: DCE-MRI was performed in 25 patients with proven or known haematological malignancies. Time-signal intensity curves (TIC) analysis was generated from the region of the iliac crest corresponding to the planned biopsy site. Enhancement characteristics were analyzed, including peak enhance ratio (PER), maximum slope (Slope max ), time to peak (TTP), and mean time (MT). The parameters of the marrow histology included cellularity and tumour fraction (TF). Results: The median of PER, Slope max , TTP, and MT in bone marrow with haematological malignancies were 0.27, 0.21 s -1 , 79.08 s and 84.43 s, respectively. The median of DCE-MR variation in bone marrow for hypo-, normal, and hyper-, cellularity groups were PER (0.29, 0.24, 1.15), Slope max (0.20 s -1 , 0.21 s -1 1.28 s -1 ), TTP (96.67 s, 83.49 s, 25.52 s), MT(77.52 s, 86.25 s, 84.34 s), respectively. The median of PER, Slope max , TTP, and MT in bone marrow for the tumor recurrence group and the remission group were 0.32, 0.28 s -1 , 68.66 s, 84.34 s, and 0.20, 0.20 s -1 , 85.85 s, 84.52 s, respectively. There was significant difference for mean PER value between the tumor recurrence group and the remission group (P = 0.02). But there were no significant difference for mean S1ope max , TFP, and MT values between the tumor recurrence group and the remission group (P>0.05). A positive correlation was found between PER and cellularity (r=0.564, P=0.003), between S1ope max and cellularity (r=0.478, P=0.016), between MT and cellularity (r=0.186). A negative correlation was found between TTP and cellularity (r=-0.222). A positive correlation was found between PER and TF (r=0.561, P=0.004), between S1ope max and TF(r=0.318, P=0.121), between MT and TF (r=0.207, P>0.05). A negative correlation was found

  12. Numerical investigation of geometric parameter effects on the aerodynamic performance of a Bladeless fan

    Directory of Open Access Journals (Sweden)

    Mohammad Jafari

    2016-03-01

    Full Text Available Aerodynamic performance of a Bladeless fan is numerically investigated considering the effect of five geometric parameters. Airflow through this fan was analyzed by simulating a Bladeless fan within a 2 m × 2 m × 4 m room. Analysis of the flow field inside the fan and the evaluation of its performance were obtained by solving conservations of mass and momentum equations for the aerodynamic investigations. In order to design the Bladeless fan an Eppler 473 airfoil profile was used as the cross section of the fan. Five distinct parameters, namely height of cross section of the fan, outlet angle of the flow relative to the fan axis, thickness of airflow outlet slit, hydraulic diameter, and aspect ratio for circular and quadratic cross sections were considered. Validating 3-D numerical results, experimental results of a round jet showed good agreement with those of the simulation data. The multiplier factor M is defined to show the ratio of the outlet flow rate to inlet flow rate from the fan. The obtained numerical results showed that the Discharge ratio has the maximum value for the height of 3 cm. The numerical outcomes of outlet thickness variation indicate that this parameter is one of the most influential parameters on the aerodynamic performance of a Bladeless fan. The results for the outlet thicknesses of 1, 2 and 3 mm showed that the Discharge ratio increased significantly when the outlet thickness decreased.

  13. Estimates of genetic parameters and environmental effects for measures of hunting performance in Finnish hounds.

    Science.gov (United States)

    Liinamo, A E; Karjalainen, L; Ojala, M; Vilva, V

    1997-03-01

    Data from field trials of Finnish Hounds between 1988 and 1992 in Finland were used to estimate genetic parameters and environmental effects for measures of hunting performance using REML procedures and an animal model. The original data set included 28,791 field trial records from 5,666 dogs. Males and females had equal hunting performance, whereas experience acquired by age improved trial results compared with results for young dogs (P Hounds with respect to their hunting ability should be based on animal model BLUP methods instead of mere performance testing. The evaluation system of field trials should also be revised for more reliability.

  14. Evaluating the Performance of Polynomial Regression Method with Different Parameters during Color Characterization

    Directory of Open Access Journals (Sweden)

    Bangyong Sun

    2014-01-01

    Full Text Available The polynomial regression method is employed to calculate the relationship of device color space and CIE color space for color characterization, and the performance of different expressions with specific parameters is evaluated. Firstly, the polynomial equation for color conversion is established and the computation of polynomial coefficients is analysed. And then different forms of polynomial equations are used to calculate the RGB and CMYK’s CIE color values, while the corresponding color errors are compared. At last, an optimal polynomial expression is obtained by analysing several related parameters during color conversion, including polynomial numbers, the degree of polynomial terms, the selection of CIE visual spaces, and the linearization.

  15. An Integrated Lumped Parameter-CFD approach for off-design ejector performance evaluation

    International Nuclear Information System (INIS)

    Besagni, Giorgio; Mereu, Riccardo; Chiesa, Paolo; Inzoli, Fabio

    2015-01-01

    Highlights: • We validate a CFD approach for a convergent nozzle ejector using global and local measurement. • We evaluate seven RANS turbulence models for convergent nozzle ejector. • We introduce a lumped parameter model for on-design and off-design ejector performance evaluation. • We analyze the relationship between local flow behavior and lumped parameters of the model. • We discuss how to improve predicting capabilities of the model by variable parameters calibrated on CFD simulations. - Abstract: This paper presents an Integrated Lumped Parameter Model-Computational Fluid-Dynamics approach for off-design ejector performance evaluation. The purpose of this approach is to evaluate the entrainment ratio, for a fixed geometry, in both on-design and off-design operating conditions. The proposed model is based on a Lumped Parameter Model (LPM) with variable ejector component efficiencies provided by CFD simulations. The CFD results are used for developing maps for ejector component efficiencies in a broad range of operating conditions. The ejector component efficiency maps couple the CFD and the LPM techniques for building an Integrated LPM-CFD approach. The proposed approach is demonstrated for a convergent nozzle ejector and the paper is structured in four parts. At first, the CFD approach is validated by global and local data and seven Reynolds Averaged Navier Stokes (RANS) turbulence models are compared: the k–ω SST showed good performance and was selected for the rest of the analysis. At second, a Lumped Parameter Model (LPM) for subsonic ejector is developed and the ejector component efficiencies have been defined. At third, the CFD approach is used to investigate the flow field, to analyze its influence on ejector component efficiencies and to propose efficiency correlations and maps linking ejector component efficiencies and local flow quantities. In the last part, the efficiency maps are embedded into the lumped parameter model, thus creating

  16. Growth performance, haematology and cost benefit of growing ...

    African Journals Online (AJOL)

    Growing rabbits on 24-h feed access time (control) recorded a higher (p0.05) across the feed access time and restriction duration. White blood cell was higher in growing rabbits on 2-h feed access ...

  17. Growth Performance, Haematological Indices and Cost Benefits of ...

    African Journals Online (AJOL)

    Lenovo pc

    2College of Animal Science and Livestock Production ... composition of CPM and diets used were determined using standard procedures. ... It was concluded that cassava peel meal can totally replace maize with or without enzyme ... In Nigeria, the livestock sector has not ... livestock for promoting health and economy of.

  18. Differences in morphological parameters of judo athletes of different age groups and performance level

    Directory of Open Access Journals (Sweden)

    Miloš Štefanovský

    2017-12-01

    Full Text Available Background: Some studies have pointed out the influence of morphological parameters on judo performance, however the relationship between morphological variables and performance status have not yet been confirmed. In addition, there is a lack of studies focused on morphological comparison of different age categories. Objective: The aim of this study was to assess differences in the morphological parameters of judo athletes of different age and performance level. Methods: The research sample was composed of 47 male judokas (age 19.15 ± 2.93 years; body weight 77.16 ± 11.39 kg; height 178.91 ± 6.39 cm; sport age 11.47 ± 2.74 years. It was divided by: (1 age, into cadets (15-17 years, n = 19, juniors (18-20 years, n = 15, and seniors (21+ years, n = 13 category and (2 performance status (elite, n = 10; non-elite, n = 37. In all participants, body fat, and the circumference measurement of wrist, forearm, flexed arm, and calf were observed. A personal interview was used to gain information about the athlete's performance status. Results: We found out that there are significant differences in arm circumference between cadets and seniors, cadets and juniors, juniors and seniors; and in the circumference of forearm between cadets and seniors; cadets and juniors, as well. According to the performance status, we have discovered significantly higher circumference of forearm and wrist in the elite group compared to the non-elite group. Conclusion: Forearm and wrist circumference is a reliable discriminative factor and should be taken into consideration, especially when selecting judo athletes into elite teams. However, we did not confirm that subcutaneous fat is a parameter able to distinguish between judo athletes of different performance status across various age categories.

  19. Biosimilars for Haematologic Malignancies: The Path to Sustainable Care

    Directory of Open Access Journals (Sweden)

    Paul Cornes

    2017-08-01

    Full Text Available The main objectives of this symposium were to review the value of biosimilars in sustainable treatment for haematologic malignancies and to recognise the developmental differences between biosimilars and their reference products. The meeting also aimed to evaluate the data on monoclonal antibodies for the treatment of haematologic malignancies and the role of biosimilars to address gaps in healthcare. Dr Cornes highlighted recent innovations in cancer treatment and presented biosimilars as economic tools that can address the financial issues that hamper progress. Prof Vulto discussed the need for healthcare professionals to be well informed about the principles of biosimilarity and aware of current and emerging therapies. Prof Jurczak presented the case for rituximab (and its biosimilars as the standard of care for first-line B cell non-Hodgkin’s lymphoma (NHL and its potential as maintenance treatment for indolent NHL (iNHL.

  20. Haematological disorders in Thorotrast-administered patients in Japan

    International Nuclear Information System (INIS)

    Kamiyama, Ryuichi; Hatakeyama, Shigeru

    1989-01-01

    Fifteen haematological disorders including ten leukaemia cases, one primary acquired sideroblastic anaemia and four aplastic anaemia cases were studied clinicopathologically in autopsies from patients who had been administered Thorotrast in Japan. The leukaemia group, the primary acquired sideroblastic anaemia and the aplastic anaemia cases after Thorotrast administration were considered to be mainly atypical, and it was speculated that damage induced by Thorotrast may affect the haemopoietic stem cell level and the haemopoietic microenvironment. Both dose rate and absorbed dose estimated in bone marrow, spleen and liver at autopsy showed no significant difference between the leukaemia group, primary acquired sideroblastic anaemia, aplastic anaemia and non-haematological disorders excluding the malignant hepatic tumours and liver cirrhosis. (author)

  1. The role of extracellular histones in haematological disorders.

    Science.gov (United States)

    Alhamdi, Yasir; Toh, Cheng-Hock

    2016-06-01

    Over the past decades, chromosomal alterations have been extensively investigated for their pathophysiological relevance in haematological malignancies. In particular, epigenetic modifications of intra-nuclear histones are now known as key regulators of healthy cell cycles that have also evolved into novel therapeutic targets for certain blood cancers. Thus, for most haematologists, histones are DNA-chained proteins that are buried deep within chromatin. However, the plot has deepened with recent revelations on the function of histones when unchained and released extracellularly upon cell death or from activated neutrophils as part of neutrophil extracellular traps (NETs). Extracellular histones and NETs are increasingly recognized for profound cytotoxicity and pro-coagulant effects. This article highlights the importance of recognizing this new paradigm of extracellular histones as a key player in host defence through its damage-associated molecular patterns, which could translate into novel diagnostic and therapeutic biomarkers in various haematological and critical disorders. © 2016 John Wiley & Sons Ltd.

  2. Investigation of the Influence of Hydrocyclone Geometric and Flow Parameters on Its Performance Using CFD

    Directory of Open Access Journals (Sweden)

    Oboetswe Seraga Motsamai

    2010-01-01

    Full Text Available Effectiveness and efficiency of hydro-cyclone separators are highly dependent on their geometrical parameters and flow characteristics. Performance of the hydro-cyclone can, therefore, be improved by modifying the geometrical parameters or flow characteristics. The mining and chemical industries are faced with problems of separating ore-rich stones from the nonore-rich stones. Due to this problem a certain amount of precious metals is lost to the dumping sites. Plant managers try to solve these problems by stockpiling what could be useless stones, so that they can be reprocessed in the future. Reprocessing is not a sustainable approach, because the reprocessed material would give lower yield as compared to the production costs. Particulate separation in a hydro-cyclone has been investigated in this paper, by using computational fluid dynamics. The paper investigated the influence of various flow and geometric parameters on particulate separation. Optimal parameters for efficient separation have been determined for the density of fluid, diameter of the spigot, and diameter of the vortex finder. The principal contribution of this paper is that key parameters for design optimization of the hydro-cyclone have been investigated.

  3. Effect of pineapple ( Ananas comosus ) on haematological and ...

    African Journals Online (AJOL)

    Each rat of batch 2, has received by cramming, 0.06 ml/kg of body weight for each day of the stalk against 0.12 ml per kg of body weight for each day for batch no. 3. The batch no. 4 has been addicted to Doliprane® (2 g / kg of body weight for each day) and was not treated with A. comosus. A haematological study plus ...

  4. Influences of some parameters on the performance of a small vertical axis wind turbine

    Directory of Open Access Journals (Sweden)

    Dumitrache Alexandru

    2016-01-01

    Full Text Available The effects of various parameters on the performance of a straight bladed vertical axis wind turbine, using the vortex model, have been numerically investigated. A vortex model has been used to evaluate the performance of a vertical axis wind turbine, by means of aerodynamic characteristics of different airfoils for Reynolds numbers between 105 and 106. Parameters such as the thickness and the camber of the blade airfoil, the solidity, the type of blade profile, the number of blades and the pitch angle, which influence the power coefficient, CP, and the start-up regime. This study can be used in the designing an optimal vertical axis wind turbine in a specific location, when the prevailed wind regime is known.

  5. Analysis report for WIPP colloid model constraints and performance assessment parameters

    Energy Technology Data Exchange (ETDEWEB)

    Mariner, Paul E.; Sassani, David Carl

    2014-03-01

    An analysis of the Waste Isolation Pilot Plant (WIPP) colloid model constraints and parameter values was performed. The focus of this work was primarily on intrinsic colloids, mineral fragment colloids, and humic substance colloids, with a lesser focus on microbial colloids. Comments by the US Environmental Protection Agency (EPA) concerning intrinsic Th(IV) colloids and Mg-Cl-OH mineral fragment colloids were addressed in detail, assumptions and data used to constrain colloid model calculations were evaluated, and inconsistencies between data and model parameter values were identified. This work resulted in a list of specific conclusions regarding model integrity, model conservatism, and opportunities for improvement related to each of the four colloid types included in the WIPP performance assessment.

  6. The effects of operation parameter on the performance of a solar-powered adsorption chiller

    International Nuclear Information System (INIS)

    Luo, Huilong; Wang, Ruzhu; Dai, Yanjun

    2010-01-01

    A solar-powered adsorption chiller with heat and mass recovery cycle was designed and constructed. It consists of a solar water heating unit, a silica gel-water adsorption chiller, a cooling tower and a fan coil unit. The adsorption chiller includes two identical adsorption units and a second stage evaporator with methanol working fluid. The effects of operation parameter on system performance were tested successfully. Test results indicated that the COP (coefficient of performance) and cooling power of the solar-powered adsorption chiller could be improved greatly by optimizing the key operation parameters, such as solar hot water temperature, heating/cooling time, mass recovery time, and chilled water temperature. Under the climatic conditions of daily solar radiation being about 16-21 MJ/m 2 , this solar-powered adsorption chiller can produce a cooling capacity about 66-90 W per m 2 collector area, its daily solar cooling COP is about 0.1-0.13.

  7. Slot Parameter Optimization for Multiband Antenna Performance Improvement Using Intelligent Systems

    Directory of Open Access Journals (Sweden)

    Erdem Demircioglu

    2015-01-01

    Full Text Available This paper discusses bandwidth enhancement for multiband microstrip patch antennas (MMPAs using symmetrical rectangular/square slots etched on the patch and the substrate properties. The slot parameters on MMPA are modeled using soft computing technique of artificial neural networks (ANN. To achieve the best ANN performance, Particle Swarm Optimization (PSO and Differential Evolution (DE are applied with ANN’s conventional training algorithm in optimization of the modeling performance. In this study, the slot parameters are assumed as slot distance to the radiating patch edge, slot width, and length. Bandwidth enhancement is applied to a formerly designed MMPA fed by a microstrip transmission line attached to the center pin of 50 ohm SMA connecter. The simulated antennas are fabricated and measured. Measurement results are utilized for training the artificial intelligence models. The ANN provides 98% model accuracy for rectangular slots and 97% for square slots; however, ANFIS offer 90% accuracy with lack of resonance frequency tracking.

  8. Parameters affecting the life cycle performance of PV technologies and systems

    International Nuclear Information System (INIS)

    Pacca, Sergio; Sivaraman, Deepak; Keoleian, Gregory A.

    2007-01-01

    This paper assesses modeling parameters that affect the environmental performance of two state-of-the-art photovoltaic (PV) electricity generation technologies: the PVL136 thin film laminates and the KC120 multi-crystalline modules. We selected three metrics to assess the modules' environmental performance, which are part of an actual 33 kW installation in Ann Arbor, MI. The net energy ratio (NER), the energy pay back time (E-PBT), and the CO 2 emissions are calculated using process based LCA methods. The results reveal some of the parameters, such as the level of solar radiation, the position of the modules, the modules' manufacturing energy intensity and its corresponding fuel mix, and the solar radiation conversion efficiency of the modules, which affect the final analytical results. A sensitivity analysis shows the effect of selected parameters on the final results. For the baseline scenario, the E-PBT for the PVL136 and KC120 are 3.2 and 7.5 years, respectively. When expected future conversion efficiencies are tested, the E-PBT is 1.6 and 5.7 years for the PVL136 and the KC120, respectively. Based on the US fuel mix, the CO 2 emissions for the PVL136 and the KC120 are 34.3 and 72.4 g of CO 2 /kW h, respectively. The most effective way to improve the modules' environmental performance is to reduce the energy input in the manufacturing phase of the modules, provided that other parameters remain constant. Consequently, the use of PV as an electricity source during PV manufacturing is also assessed. The NER of the supplier PV is key for the performance of this scheme. The results show that the NER based on a PV system can be 3.7 times higher than the NER based on electricity supplied by the traditional grid mix, and the CO 2 emissions can be reduced by 80%

  9. The effect of various parameters of large scale radio propagation models on improving performance mobile communications

    Science.gov (United States)

    Pinem, M.; Fauzi, R.

    2018-02-01

    One technique for ensuring continuity of wireless communication services and keeping a smooth transition on mobile communication networks is the soft handover technique. In the Soft Handover (SHO) technique the inclusion and reduction of Base Station from the set of active sets is determined by initiation triggers. One of the initiation triggers is based on the strong reception signal. In this paper we observed the influence of parameters of large-scale radio propagation models to improve the performance of mobile communications. The observation parameters for characterizing the performance of the specified mobile system are Drop Call, Radio Link Degradation Rate and Average Size of Active Set (AS). The simulated results show that the increase in altitude of Base Station (BS) Antenna and Mobile Station (MS) Antenna contributes to the improvement of signal power reception level so as to improve Radio Link quality and increase the average size of Active Set and reduce the average Drop Call rate. It was also found that Hata’s propagation model contributed significantly to improvements in system performance parameters compared to Okumura’s propagation model and Lee’s propagation model.

  10. Numerical investigation of geometric parameter effects on the aerodynamic performance of a Bladeless fan

    OpenAIRE

    Mohammad Jafari; Hossein Afshin; Bijan Farhanieh; Atta Sojoudi

    2016-01-01

    Aerodynamic performance of a Bladeless fan is numerically investigated considering the effect of five geometric parameters. Airflow through this fan was analyzed by simulating a Bladeless fan within a 2 m × 2 m × 4 m room. Analysis of the flow field inside the fan and the evaluation of its performance were obtained by solving conservations of mass and momentum equations for the aerodynamic investigations. In order to design the Bladeless fan an Eppler 473 airfoil profile was used as the cross...

  11. The Association of Sprint Performance with Anthropometric Parameters in Youth Soccer Players

    Directory of Open Access Journals (Sweden)

    Arjan Hyka

    2017-02-01

    Full Text Available Several studies have investigated the association between strength and speed, showing that stronger athletes perform better during sprint performances (Baker & Nance, 1999. Moreover, the aim of this study was to evaluate the correlation between sprint performance and anthropometric parameters. Subjects were 32 youth soccer players. The age of participants was 15.1±0.3 years. Speed time (50 m sprint was evaluated during sprint test, and anthropometric parameters were measured (weight, height, percent body fat. Correlation analysis (Pearson test was performed to evaluate the correlation between speed and anthropometrics. Results showed correlation between body weight and speed (r=-0.041 Sig=0.834; BMI values and speed (r=0.231; Sig=0.236, body height and speed (r=-0.384; Sig=0.044; percent body fat and speed (r=0.440; Sig=0.019.In conclusion, the results of this study show no significance association between body weight and BMI with sprint performance and significance correlation between body height (negative correlation and percent body fat (positive correlation with speed.

  12. Effect of squat depth on performance and biomechanical parameters of countermovement vertical jump

    Directory of Open Access Journals (Sweden)

    Rodrigo Ghedini Gheller

    2014-10-01

    Full Text Available DOI: http://dx.doi.org/10.5007/1980-0037.2014v16n6p658   The aim of this study was to analyze the effect of different squat depths in the performance and biomechanical parameters at counter movement jump (CMJ. Twenty-two male volleyball or basketball players volunteered to participate in this study and all were currently competing at the college level. The CMJ was performed in three different conditions: 1 with relative knee flexion at the end of counter movement phase smaller than 90° (90°, and; 3 preferred position (PREF. During the CMJ, kinematic, kinetic, and electromyography parameters were assessed. ANOVA for repeated measures with post-hoc Bonferroni´s test was used for variables comparison, with a significance level set at p≤0.05. The higher performance was on PREF and 90°. Average and peak power, as well as absolute and normalized peak forces, were higher in >90° CMJ. The peak velocity of CG and angular velocities of hip and knee were higher in the 90°. Recuts femoris and biceps femoris did not show difference in any jump phases. In conclusion, the knee flexion interferes the performance and the biomechanical variables at the CMJ. The highest jumps were got at a deeper squat, so this technique could be used for athletes in order to optimize the vertical jump performance in the training and competitions.

  13. Experimental study of dual fuel engine performance using variable LPG composition and engine parameters

    International Nuclear Information System (INIS)

    Elnajjar, Emad; Selim, Mohamed Y.E.; Hamdan, Mohammad O.

    2013-01-01

    Highlights: • The effect of using variable LPG is studied. • Five fuels with propane to butane % volume ratio are: 100-70-55-25-0. • 100% Propane composition shows the highest noise levels with similar performance. • At 45° BTDC injection timing 55% Propane LPG the only fuel experience knocking. • LPG fuels gave similar engine performance, with differences in levels of noise. - Abstract: The present work investigates experimentally the effect of LPG fuel with different composition and engine parameters on the performance of a dual compression engine. Five different blends of LPG fuels are used with Propane to Butane volume ratio of 100:0, 70:30, 55:45, 25:75, and 0:100. A single cylinder, naturally aspirated, four strokes, indirectly injected, water cooled modified Ricardo E6 engine, is used in this study. The study is carried out by measuring the cylinder pressure, engine load, engine speed, crank angle, and the fuel’s flow rate. The engine performance under variable LPG fuel composition, engine load, pilot fuel injection timing, compression ratio, pilot fuel mass and engine speed, are estimated by comparing the following engine parameters: the cylinder maximum pressure, the indicated mean effective pressure, the maximum rate of pressure rise, and the thermal efficiency. The experimental data indicates that the engine parameters are playing a major role on the engine’s performance. Different LPG fuel composition did not show a major effect on the engine efficiency but directly impacted the levels of generated combustion noise

  14. Effects of Khaya senegalensis leaves on performance, carcass traits, hemtological and biochemical parameters in rabbits

    Science.gov (United States)

    Abdel-Wareth, A. A. A.; Hammad, Seddik; Ahmed, Hassan

    2014-01-01

    One of the challenges facing farmers today is to ensure adequate integration of natural resources into animal feeds. The aim of the present study is to evaluate the effects of Khaya senegalensis (KS) leaves on the performance of growing male rabbits, carcass traits and biochemical as well as hematological parameters. Thirty New Zealand White male growing rabbits were randomly divided into 3 groups (10 rabbits per group). Group I (control) received standard rabbit diet. Rabbits in group II and group III were fed standard rabbit diet supplemented with 35 % and 65 % KS leaves, respectively. All rabbits were fed daily for 25 days. The performance parameters and carcass criteria, including daily body weight gain, final body weight, and the percentage of dressing, were increased in rabbits fed 35 % KS when compared to the control group. Kidney and liver weight ratios increased significantly in group II but dropped in group III. Furthermore, liver enzymes - alanine aminotransferase and aspartate transaminase and kidney function parameters - urea, and creatinine - increased in both group II (significant P<0.05) and in group III (significant P<0.01) when compared to the control group. Moreover, KS leaves induced a significant increase (P<0.05) in the total white blood cell count, the percentage of granulocytes and the platelet count; whereas, the percentage of lymphocytes, red blood cell count, hemoglobin content, mean corpuscular hemoglobin, mean corpuscular volume and mean corpuscular hemoglobin concentration were not statistically significantly changed. This study demonstrates that the performance parameters and carcass traits are improved by the replacement of rabbit's diet with KS leaves. However, KS leaves may adversely affect liver and kidney function in a dose-dependent manner. Therefore, further studies are required to elucidate the maximum tolerable and toxic, as well as lethal doses, and to isolate the pharmacologically active components from KS leaves. PMID

  15. Dependence of the source performance on plasma parameters at the BATMAN test facility

    Science.gov (United States)

    Wimmer, C.; Fantz, U.

    2015-04-01

    The investigation of the dependence of the source performance (high jH-, low je) for optimum Cs conditions on the plasma parameters at the BATMAN (Bavarian Test MAchine for Negative hydrogen ions) test facility is desirable in order to find key parameters for the operation of the source as well as to deepen the physical understanding. The most relevant source physics takes place in the extended boundary layer, which is the plasma layer with a thickness of several cm in front of the plasma grid: the production of H-, its transport through the plasma and its extraction, inevitably accompanied by the co-extraction of electrons. Hence, a link of the source performance with the plasma parameters in the extended boundary layer is expected. In order to characterize electron and negative hydrogen ion fluxes in the extended boundary layer, Cavity Ring-Down Spectroscopy and Langmuir probes have been applied for the measurement of the H- density and the determination of the plasma density, the plasma potential and the electron temperature, respectively. The plasma potential is of particular importance as it determines the sheath potential profile at the plasma grid: depending on the plasma grid bias relative to the plasma potential, a transition in the plasma sheath from an electron repelling to an electron attracting sheath takes place, influencing strongly the electron fraction of the bias current and thus the amount of co-extracted electrons. Dependencies of the source performance on the determined plasma parameters are presented for the comparison of two source pressures (0.6 Pa, 0.45 Pa) in hydrogen operation. The higher source pressure of 0.6 Pa is a standard point of operation at BATMAN with external magnets, whereas the lower pressure of 0.45 Pa is closer to the ITER requirements (p ≤ 0.3 Pa).

  16. Dependence of the source performance on plasma parameters at the BATMAN test facility

    International Nuclear Information System (INIS)

    Wimmer, C.; Fantz, U.

    2015-01-01

    The investigation of the dependence of the source performance (high j H − , low j e ) for optimum Cs conditions on the plasma parameters at the BATMAN (Bavarian Test MAchine for Negative hydrogen ions) test facility is desirable in order to find key parameters for the operation of the source as well as to deepen the physical understanding. The most relevant source physics takes place in the extended boundary layer, which is the plasma layer with a thickness of several cm in front of the plasma grid: the production of H − , its transport through the plasma and its extraction, inevitably accompanied by the co-extraction of electrons. Hence, a link of the source performance with the plasma parameters in the extended boundary layer is expected. In order to characterize electron and negative hydrogen ion fluxes in the extended boundary layer, Cavity Ring-Down Spectroscopy and Langmuir probes have been applied for the measurement of the H − density and the determination of the plasma density, the plasma potential and the electron temperature, respectively. The plasma potential is of particular importance as it determines the sheath potential profile at the plasma grid: depending on the plasma grid bias relative to the plasma potential, a transition in the plasma sheath from an electron repelling to an electron attracting sheath takes place, influencing strongly the electron fraction of the bias current and thus the amount of co-extracted electrons. Dependencies of the source performance on the determined plasma parameters are presented for the comparison of two source pressures (0.6 Pa, 0.45 Pa) in hydrogen operation. The higher source pressure of 0.6 Pa is a standard point of operation at BATMAN with external magnets, whereas the lower pressure of 0.45 Pa is closer to the ITER requirements (p ≤ 0.3 Pa)

  17. Approaches to characterise chromatographic column performance based on global parameters accounting for peak broadening and skewness.

    Science.gov (United States)

    Baeza-Baeza, J J; Pous-Torres, S; Torres-Lapasió, J R; García-Alvarez-Coque, M C

    2010-04-02

    Peak broadening and skewness are fundamental parameters in chromatography, since they affect the resolution capability of a chromatographic column. A common practice to characterise chromatographic columns is to estimate the efficiency and asymmetry factor for the peaks of one or more solutes eluted at selected experimental conditions. This has the drawback that the extra-column contributions to the peak variance and skewness make the peak shape parameters depend on the retention time. We propose and discuss here the use of several approaches that allow the estimation of global parameters (non-dependent on the retention time) to describe the column performance. The global parameters arise from different linear relationships that can be established between the peak variance, standard deviation, or half-widths with the retention time. Some of them describe exclusively the column contribution to the peak broadening, whereas others consider the extra-column effects also. The estimation of peak skewness was also possible for the approaches based on the half-widths. The proposed approaches were applied to the characterisation of different columns (Spherisorb, Zorbax SB, Zorbax Eclipse, Kromasil, Chromolith, X-Terra and Inertsil), using the chromatographic data obtained for several diuretics and basic drugs (beta-blockers). Copyright (c) 2010 Elsevier B.V. All rights reserved.

  18. An investigation of engine performance parameters and artificial intelligent emission prediction of hydrogen powered car

    International Nuclear Information System (INIS)

    Ho, Tien; Karri, Vishy; Lim, Daniel; Barret, Danny

    2008-01-01

    With the depletion of fossil fuel resources and the potential consequences of climate change due to fossil fuel use, much effort has been put into the search for alternative fuels for transportation. Although there are several potential alternative fuels, which have low impact on the environment, none of these fuels have the ability to be used as the sole 'fuel of the future'. One fuel which is likely to become a part of the over all solution to the transportation fuel dilemma is hydrogen. In this paper, The Toyota Corolla four cylinder, 1.8 l engine running on petrol is systematically converted to run on hydrogen. Several ancillary instruments for measuring various engine operating parameters and emissions are fitted to appraise the performance of the hydrogen car. The effect of hydrogen as a fuel compares with gasoline on engine operating parameters and effect of engine operating parameters on emission characteristics is discussed. Based on the experimental setup, a suite of neural network models were tested to accurately predict the effect of major engine operating conditions on the hydrogen car emissions. Predictions were found to be ±4% to the experimental values. This work provided better understanding of the effect of engine process parameters on emissions. (author)

  19. Selection of the battery pack parameters for an electric vehicle based on performance requirements

    Science.gov (United States)

    Koniak, M.; Czerepicki, A.

    2017-06-01

    Each type of vehicle has specific power requirements. Some require a rapid charging, other make long distances between charges, but a common feature is the longest battery life time. Additionally, the battery is influenced by factors such as temperature, depth of discharge and the operation current. The article contain the parameters of chemical cells that should be taken into account during the design of the battery for a specific application. This is particularly important because the batteries are not properly matched and can wear prematurely and cause an additional costs. The method of selecting the correct cell type should take previously discussed features and operating characteristics of the vehicle into account. The authors present methods of obtaining such characteristics along with their assessment and examples. Also there has been described an example of the battery parameters selection based on design assumptions of the vehicle and the expected performance characteristics. Selecting proper battery operating parameters is important due to its impact on the economic result of investments in electric vehicles. For example, for some Li-Ion technologies, the earlier worn out of batteries in a fleet of cruise boats or buses having estimated lifetime of 10 years is not acceptable, because this will cause substantial financial losses for the owner of the rolling stock. The presented method of choosing the right cell technology in the selected application, can be the basis for making the decision on future battery technical parameters.

  20. A review on heat sink for thermo-electric power generation: Classifications and parameters affecting performance

    International Nuclear Information System (INIS)

    Elghool, Ali; Basrawi, Firdaus; Ibrahim, Thamir Khalil; Habib, Khairul; Ibrahim, Hassan; Idris, Daing Mohamad Nafiz Daing

    2017-01-01

    Highlights: • Coupling a thermoelectric power generation (TEG) to a heat sink is presented. • Review the classifications and parameters affecting performance of the TEG with heat sink. • Discuss different mathematical models of the heat sinks. • The passive heat sinks are most appropriate because of the inherent efficiency of TEG. • Medium temperature range below 300 °C is found to be most suitable for HPHS. - Abstract: In recent years, there have been growing interests in key areas related to global warming resulting from environmental emissions, and the diminishing sources of fossil fuel. The increased interest has led to significant research efforts towards finding novel technologies in clean energy production. Consequently, the merits of a thermo-electric generator (TEG) have promised a revival of alternative means of producing green energy. It is, however, impractical to account for the cost of thermal energy input to the TEG which is in the form of final waste heat. This is because the technology presents critical limitations in determining its cost efficiency nor its economic disadvantages. This paper reviews the principles of thermo-electric power production, as well the materials use, performance achieved, and application areas. The paper also takes a particular deliberation on TEG heat sinks geometries and categories. The review emphasizes more on the TEG performance while considering a number of heat sink parameters related to its performance.

  1. Performance-based parameter tuning method of model-driven PID control systems.

    Science.gov (United States)

    Zhao, Y M; Xie, W F; Tu, X W

    2012-05-01

    In this paper, performance-based parameter tuning method of model-driven Two-Degree-of-Freedom PID (MD TDOF PID) control system has been proposed to enhance the control performances of a process. Known for its ability of stabilizing the unstable processes, fast tracking to the change of set points and rejecting disturbance, the MD TDOF PID has gained research interest recently. The tuning methods for the reported MD TDOF PID are based on internal model control (IMC) method instead of optimizing the performance indices. In this paper, an Integral of Time Absolute Error (ITAE) zero-position-error optimal tuning and noise effect minimizing method is proposed for tuning two parameters in MD TDOF PID control system to achieve the desired regulating and disturbance rejection performance. The comparison with Two-Degree-of-Freedom control scheme by modified smith predictor (TDOF CS MSP) and the designed MD TDOF PID tuned by the IMC tuning method demonstrates the effectiveness of the proposed tuning method. Copyright © 2012 ISA. Published by Elsevier Ltd. All rights reserved.

  2. Hematologia de teleósteos brasileiros com infecção parasitária. I. Variáveis do Leporinus macrocephalus Garavelo e Britski, 1988 (Anostomidae e Piaractus mesopotamicus Holmberg, 1887 (Characidae Haematology of parasitized Brazilian teleost fishes. I. Parameters of Leporinus macrocephalus Garavelo and Britski, 1988 (Anostomidae and Piaractus mesopotamicus Holmberg, 1887 (Characidae

    Directory of Open Access Journals (Sweden)

    Dilermando Perecin

    1999-07-01

    Full Text Available Espécimes de Leporinus macrocephalus (piauçu e de Piaractus mesopotamicus (pacu foram colhidos em piscicultura do município de Franca (SP para avaliação dos efeitos da infecção parasitária sobre a taxa de hemoglobina e de hematócrito, a concentração de hemoglobina corpuscular média (CHCM, o fator relativo de condição (Kn e a distribuição percentual de células sangüíneas de defesa orgânica (leucócitos e trombócitos. Ambas as espécies apresentavam-se parasitadas por monogenea ou por monogenea e outros parasitas: monogenea e Trichodina sp; monogenea e Lernaea cyprinacea; monogenea e Piscinoodinium pillulare; monogenea e Ichthyophthirius multifiliis; monogenea, I. multifiliis e Trichodina sp. Os resultados demonstraram que os parâmetros estudados em L. macrocephalus e em P. mesopotamicus não foram significativamente (p > 0,05 alterados pelo parasitismo. A análise de regressão linear mostrou correlação negativa (p > 0,05 entre linfócitos e trombócitos em L. macrocephalus e correlação positiva (p > 0,01 da taxa de hemoglobina com o peso e com o comprimento total em P. mesopotamicus.Specimens of cultivated Leporinus macrocephalus (piauçu and Piaractus mesopotamicus (pacu were collected in a fishfarm at Franca, SP. Effects of parasite infection upon hemoglobin, hematocrit, mean corpuscular hemoglobin concentration (MCHC, condition factor (Kn and differential count of defense cells (leucocyte and thrombocyte were evaluated. Both fish species were parasitized by monogenean; monogenean and Trichodina sp; monogenean and Lernaea cyprinacea; monogenean and Piscinoodinium pillulare; monogenean and Ichthyophthirius miltifiliis; monogenean, I. multifiliis and Trichodina sp. Parasitism did not influence (p > 0.05 the studied haematological characteristics in L. macrocephalus and P. mesopotamicus. Linnear regression showed negative correlation (p > 0.05 between lymphocytes and thrombocytes in L. macrocephalus and positive

  3. Effect of aqueous extract of Murraya koenigii on haematological, hormonal and lipid profie of Albino rats

    Directory of Open Access Journals (Sweden)

    Sushmita Choudhury

    2015-11-01

    Full Text Available Objective: To investigate the effect of aqueous extract of Murraya koenigii leaves on some haematological, hormonal and serum lipid parameters in rats. Methods: We evaluated whether oral administration of Murraya koenigii affected the haematological, hormonal and lipid parameters. After 7 days of oral administration of 250 mg/ kg and 500 mg/kg body weight, other profiles were investigated. Results: The results showed that the extract administered significantly increased (P < 0.05 packed cell volume, haemoglobin concentration, red blood cell, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, mean corpuscular volume and decreased the platelet count (P < 0.05 at the dose of 250 mg/kg and 500 mg/kg body weight when compared with control. The extract significantly increased (P < 0.05 white blood cell count at all doses administered when compared with control. Results showed that thyronine and thyroxine were increased, while thyroid stimulating hormone was decreased significantly (P < 0.05 at high doses compared. The recorded data in the present study showed that the testosterone value was reduced significantly (P < 0.05 from control value. Also the extract significantly reduced (P < 0.05 the total cholesterol concentration and low density lipoproteins cholesterol concentration in the serum while it had no significant effect on serum high density lipoprotein cholesterol concentration at all doses administered. Conclusions: This study suggests that the extracts may have beneficial effect on serum cholesterol concentration, can act as a stimulant to thyroid functions as well as in anemia and immunity dependent disorders and also as a potent contraceptive.

  4. Sensitivity of storage field performance to geologic and cavern design parameters in salt domes.

    Energy Technology Data Exchange (ETDEWEB)

    Ehgartner, Brian L. (Sandia National Laboratories, Albuquerque, NM); Park, Byoung Yoon

    2009-03-01

    A sensitivity study was performed utilizing a three dimensional finite element model to assess allowable cavern field sizes for strategic petroleum reserve salt domes. A potential exists for tensile fracturing and dilatancy damage to salt that can compromise the integrity of a cavern field in situations where high extraction ratios exist. The effects of salt creep rate, depth of salt dome top, dome size, caprock thickness, elastic moduli of caprock and surrounding rock, lateral stress ratio of surrounding rock, cavern size, depth of cavern, and number of caverns are examined numerically. As a result, a correlation table between the parameters and the impact on the performance of storage field was established. In general, slower salt creep rates, deeper depth of salt dome top, larger elastic moduli of caprock and surrounding rock, and a smaller radius of cavern are better for structural performance of the salt dome.

  5. Effect of Composting Parameters on the Power Performance of Solid Microbial Fuel Cells

    Directory of Open Access Journals (Sweden)

    Chin-Tsan Wang

    2015-09-01

    Full Text Available Nowadays, solid organic waste is of major environmental concern and is reaching critical levels worldwide. Currently, a form of natural decomposition, known as composting technology, is widely used to deal with organic waste. This method is applied to enhance the performance of solid microbial fuel cells (SMFCs in this study. Operational composting parameters (carbon/nitrogen ratio, moisture content and pH value are investigated to explore the optimal power performance of solid microbial fuel cells (SMFCs. Results indicate that the carbon/nitrogen ratio and the moisture content displayed the most significant impact on SMFCs. When the carbon/nitrogen ratio is 31.4 and moisture content is 60%, along with a pH value of 6–8, a better SMFC power performance would be obtained. These findings would provide positive information regarding the application of compost in SMFCs.

  6. Formation Flight System Extremum-Seeking-Control Using Blended Performance Parameters

    Science.gov (United States)

    Ryan, John J. (Inventor)

    2018-01-01

    An extremum-seeking control system for formation flight that uses blended performance parameters in a conglomerate performance function that better approximates drag reduction than performance functions formed from individual measurements. Generally, a variety of different measurements are taken and fed to a control system, the measurements are weighted, and are then subjected to a peak-seeking control algorithm. As measurements are continually taken, the aircraft will be guided to a relative position which optimizes the drag reduction of the formation. Two embodiments are discussed. Two approaches are shown for determining relative weightings: "a priori" by which they are qualitatively determined (by minimizing the error between the conglomerate function and the drag reduction function), and by periodically updating the weightings as the formation evolves.

  7. Measurement of performance parameters of plasma source for plasma opening switch on Qiangguang-Ⅰ generator

    International Nuclear Information System (INIS)

    Luo Weixi; Zeng Zhengzhong; Lei Tianshi; Wang Liangping; Hu Yixiang; Sun Tieping; Huang Tao

    2012-01-01

    The plasma source (cable guns) of the plasma opening switch (POS) on Qiangguang Ⅰ generator was chosen as the study object. The plasma source performance was investigated by using charge collectors. Experimental results show that the plasma ejection density is positively correlated with the structural parameter, the distance between gun core tip and muzzle plane, and the plasma ejection velocity is negatively correlated with the parameter. The increasing rate of plasma ejection density is less than that of drive current. As far as a plasma source with tens of cable plasma guns is concerned, the influence of single cable gun's discharge dispersancy on plasma uniformity is little. Analysis of uncertainty shows that the uncertainty of measurement can be reduced by increasing the number of experiments and averaging the results. The combined standard uncertainty of plasma ejection density is less than 10%. (authors)

  8. Aerodynamic Parameters of High Performance Aircraft Estimated from Wind Tunnel and Flight Test Data

    Science.gov (United States)

    Klein, Vladislav; Murphy, Patrick C.

    1998-01-01

    A concept of system identification applied to high performance aircraft is introduced followed by a discussion on the identification methodology. Special emphasis is given to model postulation using time invariant and time dependent aerodynamic parameters, model structure determination and parameter estimation using ordinary least squares an mixed estimation methods, At the same time problems of data collinearity detection and its assessment are discussed. These parts of methodology are demonstrated in examples using flight data of the X-29A and X-31A aircraft. In the third example wind tunnel oscillatory data of the F-16XL model are used. A strong dependence of these data on frequency led to the development of models with unsteady aerodynamic terms in the form of indicial functions. The paper is completed by concluding remarks.

  9. Study of operational parameters on the performance of micro PEMFCs with different flow fields

    International Nuclear Information System (INIS)

    Hsieh, S.-S.; Yang, S.-H.; Kuo, J.-K.; Huang, C.-F.; Tsai, H.-H.

    2006-01-01

    The effects of different operating parameters on micro PEMFC performances were experimentally studied for three different flow field configurations (interdigitated, mesh, and serpentine). Experiments with different cell operating temperatures and different backpressures on the H 2 flow channels, as well as various combinations of these parameters, have been conducted for three different flow geometries. The micro PEMFCs were designed and fabricated inhouse through a deep UV lithography technique and the SU-8 photoresist was used as microstructure material for the fuel cell flow field plates. Results are presented in the form of polarization VI curves and PI curves under different operating conditions. The possible transport mechanisms associated with the parametric effects were discussed. In addition, it was found that among the three flow patterns considered, significant improvements can be reached with a specified flow geometry

  10. Effects of inverting the position of layers eggs during storage on hatchery performance parameters

    Directory of Open Access Journals (Sweden)

    JCS de Lima

    2012-12-01

    Full Text Available Storing hatchable eggs is a common practice in commercial hatcheries. However, storage time may negative effects on several performance parameters. An experiment was carried out to evaluate inverting egg position during storage of eggs laid by young and old layer breeders. Fertile eggs of 32 and 58-week-old breeders were stored for seven, 14, and 21 days at 18ºC ± 2ºC and 80% ± 10% relative humidity (RU. The following parameters were evaluated: egg weight loss, hatchability and hatchling weight, and embryodiagnosis results. Eggs stored with the small end up lost less weight during storage compared with the control eggs. Storing eggs for 14 days with the small end up reduced early embryo mortality, improving hatchability. In addition, hatchling weight increased. These results show that the detrimental effects of long storage periods may be alleviated when eggs are stored with the small end up to 14 days of storage.

  11. Parameter study on performance of building cooling by night-time ventilation

    DEFF Research Database (Denmark)

    Artmann, Nikolai; Manz, H.; Heiselberg, Per

    2008-01-01

    of different parameters such as building construction, heat gains, air change rates, heat transfer coefficients and climatic conditions including annual variations on the number of overheating degree hours (operative room temperature >26 °C) was evaluated. Climatic conditions and air flow rate during night......Especially for commercial buildings in moderate climates, night-time ventilation seems to be a simple and energy-efficient approach to improve thermal comfort in summer. However, due to uncertainties in the prediction of thermal comfort in buildings with night-time ventilation, architects...... and engineers are still hesitant to apply this technique. In order to reduce the uncertainties, the most important parameters affecting night ventilation performance need to be identified. A typical office room was therefore modelled using a building energy simulation programme (HELIOS), and the effect...

  12. The influence of design parameters on the performance of FBAR in 10-14 GHz

    Science.gov (United States)

    Nor, N. I. M.; Osman, R. A. M.; Idris, M. S.; Khalid, N.; Mohamad Isa, M.; Ahmad, N.; Mat Isa, Siti S.; Ramli, Muhammad M.; Kasjoo, S. R.

    2017-11-01

    This research presents the analysis of the influence of design parameters on the performance of film bilk acoustic wave resonator (FBAR) working from 10 GHz to 14 GHz. The analysis is done by implementing one-dimensional (1-D) modellings, which are 1-D Mason model and Butterworth Van Dyke (BVD) model. The physical parameters such as piezoelectric materials and its thickness, and size of area affecting the characteristics of the FBAR are analyzed in detail. Zinc oxide (ZnO) and aluminum nitride (AlN) are chosen as the piezoelectric materials. The resonance area is varied at 25μm×25μm to 35μm×35μm. From the analysis, it is found that as the frequency increases, the thickness of the piezoelectric material decreases. Meanwhile, the static capacitance increases as the frequency increases. It is also found that as the area increases, the electrical impedance and static capacitance also increases.

  13. Effect of Processing Parameters on Performance of Spray-Deposited Organic Thin-Film Transistors

    Directory of Open Access Journals (Sweden)

    Jack W. Owen

    2011-01-01

    Full Text Available The performance of organic thin-film transistors (OTFTs is often strongly dependent on the fabrication procedure. In this study, we fabricate OTFTs of soluble small-molecule organic semiconductors by spray-deposition and explore the effect of processing parameters on film morphology and device mobility. In particular, we report on the effect of the nature of solvent, the pressure of the carrier gas used in deposition, and the spraying distance. We investigate the surface morphology using scanning force microscopy and show that the molecules pack along the π-stacking direction, which is the preferred charge transport direction. Our results demonstrate that we can tune the field-effect mobility of spray-deposited devices two orders of magnitude, from 10−3 cm2/Vs to 10−1 cm2/Vs, by controlling fabrication parameters.

  14. Atmospheric parameters, spectral indexes and their relation to CPV spectral performance

    Energy Technology Data Exchange (ETDEWEB)

    Núñez, Rubén, E-mail: ruben.nunez@ies-def.upm.es; Antón, Ignacio, E-mail: ruben.nunez@ies-def.upm.es; Askins, Steve, E-mail: ruben.nunez@ies-def.upm.es; Sala, Gabriel, E-mail: ruben.nunez@ies-def.upm.es [Instituto de Energía Solar - Universidad Politécnica de Madrid, Instituto de Energía Solar, ETSI Telecomunicación, Ciudad Universitaria 28040 Madrid (Spain)

    2014-09-26

    Air Mass and atmosphere components (basically aerosol (AOD) and precipitable water (PW)) define the absorption of the sunlight that arrive to Earth. Radiative models such as SMARTS or MODTRAN use these parameters to generate an equivalent spectrum. However, complex and expensive instruments (as AERONET network devices) are needed to obtain AOD and PW. On the other hand, the use of isotype cells is a convenient way to characterize spectrally a place for CPV considering that they provide the photocurrent of the different internal subcells individually. Crossing data from AERONET station and a Tri-band Spectroheliometer, a model that correlates Spectral Mismatch Ratios and atmospheric parameters is proposed. Considering the amount of stations of AERONET network, this model may be used to estimate the spectral influence on energy performance of CPV systems close to all the stations worldwide.

  15. Parameters that affect parallel processing for computational electromagnetic simulation codes on high performance computing clusters

    Science.gov (United States)

    Moon, Hongsik

    What is the impact of multicore and associated advanced technologies on computational software for science? Most researchers and students have multicore laptops or desktops for their research and they need computing power to run computational software packages. Computing power was initially derived from Central Processing Unit (CPU) clock speed. That changed when increases in clock speed became constrained by power requirements. Chip manufacturers turned to multicore CPU architectures and associated technological advancements to create the CPUs for the future. Most software applications benefited by the increased computing power the same way that increases in clock speed helped applications run faster. However, for Computational ElectroMagnetics (CEM) software developers, this change was not an obvious benefit - it appeared to be a detriment. Developers were challenged to find a way to correctly utilize the advancements in hardware so that their codes could benefit. The solution was parallelization and this dissertation details the investigation to address these challenges. Prior to multicore CPUs, advanced computer technologies were compared with the performance using benchmark software and the metric was FLoting-point Operations Per Seconds (FLOPS) which indicates system performance for scientific applications that make heavy use of floating-point calculations. Is FLOPS an effective metric for parallelized CEM simulation tools on new multicore system? Parallel CEM software needs to be benchmarked not only by FLOPS but also by the performance of other parameters related to type and utilization of the hardware, such as CPU, Random Access Memory (RAM), hard disk, network, etc. The codes need to be optimized for more than just FLOPs and new parameters must be included in benchmarking. In this dissertation, the parallel CEM software named High Order Basis Based Integral Equation Solver (HOBBIES) is introduced. This code was developed to address the needs of the

  16. Key radionuclides and parameters that determine performance of geologic repositories for high-level radioactive wastes

    International Nuclear Information System (INIS)

    Joonhong Ahn; Atsuyuki Suzuki

    1993-01-01

    This paper presents results of a mathematical analysis for performance of the engineered barriers of high-level radioactive waste repositories. The main body of the mathematical model developed in this study is mass transport of actinides in a bentonite region. In an analysis of actinide transport, radioactive decay chain and effects of low solubilities must be taken into account. In many previous models for mass transport in engineered barriers including radioactive decay chain, however, boundary conditions at the interface between the waste form and the bentonite region cannot be determined flexibly. In some models, solubility-limited boundary condition is assumed for all the members in a chain. In order to investigate what are key radionuclides and parameters that control performance of engineered barriers of a geologic repository, we must evaluate mass transport with the source boundary condition determined by a detailed analysis on mass transfer at the boundary. In this study, we developed a mathematical model, which can determine whether the inner boundary condition is solubility-limited or congruent release, based on a mathematical analysis for mass transfer at the glass dissolution location, and how long the solubility-limited boundary condition applies. Based on the mathematical model, we point out radionuclides and parameters that have primary influences on the performance of a repository, and investigate a reasonable strategy for coupling geologic disposal and partitioning of those key radionuclides from the standpoint of reducing hazard of geologic disposal. (authors). 4 tabs., 2 figs., 8 refs

  17. Hydrological model performance and parameter estimation in the wavelet-domain

    Directory of Open Access Journals (Sweden)

    B. Schaefli

    2009-10-01

    Full Text Available This paper proposes a method for rainfall-runoff model calibration and performance analysis in the wavelet-domain by fitting the estimated wavelet-power spectrum (a representation of the time-varying frequency content of a time series of a simulated discharge series to the one of the corresponding observed time series. As discussed in this paper, calibrating hydrological models so as to reproduce the time-varying frequency content of the observed signal can lead to different results than parameter estimation in the time-domain. Therefore, wavelet-domain parameter estimation has the potential to give new insights into model performance and to reveal model structural deficiencies. We apply the proposed method to synthetic case studies and a real-world discharge modeling case study and discuss how model diagnosis can benefit from an analysis in the wavelet-domain. The results show that for the real-world case study of precipitation – runoff modeling for a high alpine catchment, the calibrated discharge simulation captures the dynamics of the observed time series better than the results obtained through calibration in the time-domain. In addition, the wavelet-domain performance assessment of this case study highlights the frequencies that are not well reproduced by the model, which gives specific indications about how to improve the model structure.

  18. Analysis of swimming performance from physical, physiological, and biomechanical parameters in young swimmers.

    Science.gov (United States)

    Jürimäe, Jaak; Haljaste, Kaja; Cicchella, Antonio; Lätt, Evelin; Purge, Priit; Leppik, Aire; Jürimäe, Toivo

    2007-02-01

    The purpose of this study was to examine the influence of the energy cost of swimming, body composition, and technical parameters on swimming performance in young swimmers. Twenty-nine swimmers, 15 prepubertal (11.9 +/- 0.3 years; Tanner Stages 1-2) and 14 pubertal (14.3 +/- 1.4 years; Tanner Stages 3-4) boys participated in the study. The energy cost of swimming (Cs) and stroking parameters were assessed over maximal 400-m front-crawl swimming in a 25-m swimming pool. The backward extrapolation technique was used to evaluate peak oxygen consumption (VO2peak). A stroke index (SI; m2 . s(-1) . cycles(-1)) was calculated by multiplying the swimming speed by the stroke length. VO2peak results were compared with VO2peak test in the laboratory (bicycle, 2.86 +/- 0.74 L/min, vs. in water, 2.53 +/- 0.50 L/min; R2 = .713; p = .0001). Stepwise-regression analyses revealed that SI (R2 = .898), in-water VO2peak (R2 = .358), and arm span (R2 = .454) were the best predictors of swimming performance. The backward-extrapolation method could be used to assess VO2peak in young swimmers. SI, arm span, and VO2peak appear to be the major determinants of front-crawl swimming performance in young swimmers.

  19. Impact of water temperature and structural parameters on the hydraulic labyrinth-channel emitter performance

    Directory of Open Access Journals (Sweden)

    Ahmed I. Al-Amoud

    2014-06-01

    Full Text Available The effects of water temperature and structural parameters of a labyrinth emitter on drip irrigation hydraulic performance were investigated. The inside structural parameters of the trapezoidal labyrinth emitter include path width (W and length (L, trapezoidal unit numbers (N, height (H, and spacing (S. Laboratory experiments were conducted using five different types of labyrinth-channel emitters (three non-pressure compensating and two pressure-compensating emitters commonly used for subsurface drip irrigation systems. The water temperature effect on the hydraulic characteristics at various operating pressures was recorded and a comparison was made to identify the most effective structural parameter on emitter performance. The pressure compensating emitter flow exponent (x average was 0.014, while non-pressure compensating emitter’s values average was 0.456, indicating that the sensitivity of non-pressure compensating emitters to pressure variation is an obvious characteristic (p<0.001 of this type of emitters. The effects of water temperature on emitter flow rate were insignificant (p>0.05 at various operating pressures, where the flow rate index values for emitters were around one. The effects of water temperature on manufacturer’s coefficient of variation (CV values for all emitters were insignificant (p>0.05. The CV values of the non-pressure compensating emitters were lower than those of pressure compensating emitters. This is typical for most compensating models because they are manufactured with more elements than non-compensating emitters are. The results of regression analysis indicate that N and H are the essential factors (p<0.001 to affect the hydraulic performance.

  20. Impact of Various Parameters on the Performance of Inter-aircraft Optical Wireless Communication Link

    Science.gov (United States)

    Singh, Mehtab

    2017-12-01

    Optical wireless communication (OWC) systems also known as Free space optics (FSO) are capable of providing high channel bandwidth, high data transmission rates, low power consumption, and high security. OWC links are being considered in different applications such as inter-satellite links, terrestrial links, and inter-aircraft communication links. This paper investigates the impact of different system parameters such as transmission power level, operating wavelength, transmitter pointing error angle, bit transmission rate, atmospheric attenuation, antenna aperture diameter, geometric losses, the responsivity of the photodetector, and link range on the performance of inter-aircraft optical wireless communication link.

  1. Adaptive Synchronization of Chaotic Systems considering Performance Parameters of Operational Amplifiers

    Directory of Open Access Journals (Sweden)

    Sergio Ruíz-Hernández

    2015-01-01

    Full Text Available This paper addresses an adaptive control approach for synchronizing two chaotic oscillators with saturated nonlinear function series as nonlinear functions. Mathematical models to characterize the behavior of the transmitter and receiver circuit were derived, including in the latter the adaptive control and taking into account, for both chaotic oscillators, the most influential performance parameters associated with operational amplifiers. Asymptotic stability of the full synchronization system is studied by using Lyapunov direct method. Theoretical derivations and related results are experimentally validated through implementations from commercially available devices. Finally, the full synchronization system can easily be reproducible at a low cost.

  2. Using Mathematical Modeling Methods for Estimating Entrance Flow Heterogeneity Impact on Aviation GTE Parameters and Performances

    Directory of Open Access Journals (Sweden)

    Yu. A. Ezrokhi

    2017-01-01

    Full Text Available The paper considers methodological approaches to the mathematical models (MM of various levels, dedicated to estimate an impact of the entrance flow heterogeneity on the main parameters and performances of the aviation GTE and it units. By an example of calculation of a twin-shaft turbofan engine in cruiser mode, demonstrates engineering mathematical model capabilities to define the impact of the total pressure field distortion on engine trust and air flow parameters, and also gas dynamic stability margin of the both compressors.It is shown that the presented first level mathematical model allows us to estimate sufficiently the impact of entrance total pressure heterogeneity on the engine parameters. Here reliability of calculations is proved to be true by their comparison with the results, obtained owing to well fulfilled 2D & 3D mathematical models of the engine, which have been repeatedly identified by the results of experiments.It is shown that received results including those on decreasing values of stability margin of both compressors can be used for tentative estimates when choosing a desirable stability margin, providing steady operation of compressors and engine in an entire range of its operating modes. Carrying out a definitive testing calculation using the specialized engine MM of a higher level will not only confirm the results obtained, but also reduce their expected error with regard to the real values reached as a result of tests.

  3. Determination of Performance Measuring Parameters of an Improved Dual Paraboloid Solar Cooker

    Directory of Open Access Journals (Sweden)

    Suhail Zaki Farooqui

    2017-01-01

    Full Text Available An experimental investigation into the performance evaluation of an improved dual reflector foldable paraboloid solar cooker has been reported, along with its energy and exergy analysis. The best attribute of this lightweight and low-cost solar cooker is its high performance coupled with the ease of handling. The cooker utilizes two paraboloid reflectors made out of Mylar-coated fiberglass dishes, each having a diameter of 90 cm and focal length of 105 cm. The total intercepted radiation energy is 1.08 kW under standard test conditions. Stagnation temperatures of up to 330°C and cooking temperatures of up to 290°C have been attained with load. Altogether, 9 experiments have been performed with and without load. Loaded tests have been conducted with water and vegetable oil. Results indicate an average cooking power of 485 W, peak exergy gain of 60.53 W, quality factor of 0.077, and a high product of temperature difference gap at half peak power to peak power of 4364.33 W·K. The maximum exergy output power attained was 70 W, while maximum exergy efficiency was 8–10%. All performance measuring parameters indicate that it is a high performance solar cooker for rural and urban communities and is suitable for all types of oil- and water-based cooking.

  4. Chemical and physical parameters affecting the performance of the Os-191/Ir-191m generator

    International Nuclear Information System (INIS)

    Packard, A.B.; Butler, T.A.; Knapp, F.F.; O'Brien, G.M.; Treves, S.

    1984-01-01

    The development of an Os-191/Ir-191m generator suitable for radionuclide angiography in humans has elicited much interest. This generator employs ''(OsO 2 Cl 4 ) 2- '' on AG MP-1 anion exchange resin with a Dowex-2 scavenger column and is eluted with normal saline at pH 1. The parent Os species is, however, neither welldefined nor homogeneous leading to less than optimal breakthrough of Os-191 (5 x 10 -3 %) and modest Ir-191m yield (10-15%). The effect of a range of parameters on generator performance has been evaluated as has been the way in which the assembly and loading process affects generator performance. In addition, a number of potential alternative generator systems have been evaluated

  5. Investigation of fuel lattice pitch changes influence on reactor performance through evaluate the neutronic parameters

    International Nuclear Information System (INIS)

    Zareian Ronizi, F.; Fadaei, A.H.; Setayeshi, S.; Shahidi, A.R.

    2015-01-01

    Highlights: • One of the most complex issues that Nu-engineers deal with is the design of NR core. • Numerous factors in nuclear core design depend on Fuel-to-Moderator volume ratio. • Aim of this research is to investigate RX performance for different lattice pitches. - Abstract: Nuclear reactor core design is one of the most complex issues that nuclear engineers deal with. The number and complexity of effective parameters and their impact on reactor design, which makes the problem difficult to solve, require precise knowledge of these parameters and their influence on the reactor operation. Numerous factors in a nuclear reactor core design depend on the Fuel-to-Moderator volume ratio, V F /V M , in a fuel cell. This ratio can be modified by changing the lattice pitch which is the thickness of water channels between fuels plates while keeping fuel slab dimensions fixed. Cooling and moderating properties of water are affected by such a change in a reactor core, and hence some parameters related to these properties might be changed. The aim of this research is to provide the suitable knowledge for nuclear core designing. To reach this goal, the first operating core of Tehran Research Reactor (TRR) with different lattice pitches is simulated, and the effect of different lattice pitches on some parameters such as effective multiplication factor (K eff ), reactor life time, distribution of neutron flux and power density in the core, as well as moderator temperature and density coefficient of reactivity are evaluated. The nuclear reactor analysis code, MTR-PC package is employed to carry out the considered calculation. Finally, the results are presented in some tables and graphs that provide useful information for nuclear engineers in the nuclear reactor core design

  6. Preliminary performance assessment for the Waste Isolation Pilot Plant, December 1992. Volume 3, Model parameters: Sandia WIPP Project

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-29

    This volume documents model parameters chosen as of July 1992 that were used by the Performance Assessment Department of Sandia National Laboratories in its 1992 preliminary performance assessment of the Waste Isolation Pilot Plant (WIPP). Ranges and distributions for about 300 modeling parameters in the current secondary data base are presented in tables for the geologic and engineered barriers, global materials (e.g., fluid properties), and agents that act upon the WIPP disposal system such as climate variability and human-intrusion boreholes. The 49 parameters sampled in the 1992 Preliminary Performance Assessment are given special emphasis with tables and graphics that provide insight and sources of data for each parameter.

  7. Assessment of yeast as a dietary additive on haematology and water quality of common carp in a recirculating aquaculture system

    Science.gov (United States)

    Goran, Siraj Muhammed Abdulla; Omar, Samad Sofy; Anwer, Ayub Youns

    2017-09-01

    Feeding experiment was accomplished at the Aquaculture unit (Close system), Grdarasha station, Agriculture College, University of Salahaddin, Erbil, Kurdistan Region, to investigate different levels of Aquagrow E (AGEY) brewer's yeast cell Saccharomyces cerevisiae on the haematological and water quality of common carp fingerlings Cyprinus carpio. The basal diet was formulated to contain 34% protein and 10% lipid and the dietary treatments were supplemented with 0.5%, 1% and 1.5% of AGEY diet. A total of 180 Common carp (10.30 ± 0.27 g) fed on experimental diets for 10 weeks. Water quality assessment for well water and pond water for rearing Cyprinus carpio in cage system conducted weekly, while some parameters including pH, EC, water temperature and DO were monitored daily during the entire periods of study. Values of total hardness, alkalinity, ammonia and nitrate for studied water samples were within normal ranges for rearing Cyprinus carpio. Mean concentration of GPT, GOT and Glucose were 104 to 170 U/L, 1371 to 3308 U/L and 34 to 63mg/dl respectively, moreover, highest levels were observed in treatments with higher concentrations of yeast in its food except for blood sugar. Slight variation in lipase enzyme were found between control and treatment groups, while levels of amylase enzyme were increased toward cages with higher levels of yeast until T1 and then decreased toward T3. Total protein levels were increased to toward higher levels of yeast in food of Cyprinus carpio fish. Haematological results showed highest levels of WBC and platelets in treatments cages than control group. Levels of RBCs and hemoglobin were highest in treatment group 1 with 0.5%of yeast than treatments higher yeast concentrations. Significant correlation was found in haematological parameters between control and treatments.

  8. Performance verification and system parameter identification of spacecraft tape recorder control servo

    Science.gov (United States)

    Mukhopadhyay, A. K.

    1979-01-01

    Design adequacy of the lead-lag compensator of the frequency loop, accuracy checking of the analytical expression for the electrical motor transfer function, and performance evaluation of the speed control servo of the digital tape recorder used on-board the 1976 Viking Mars Orbiters and Voyager 1977 Jupiter-Saturn flyby spacecraft are analyzed. The transfer functions of the most important parts of a simplified frequency loop used for test simulation are described and ten simulation cases are reported. The first four of these cases illustrate the method of selecting the most suitable transfer function for the hysteresis synchronous motor, while the rest verify and determine the servo performance parameters and alternative servo compensation schemes. It is concluded that the linear methods provide a starting point for the final verification/refinement of servo design by nonlinear time response simulation and that the variation of the parameters of the static/dynamic Coulomb friction is as expected in a long-life space mission environment.

  9. The role of interior watershed processes in improving parameter estimation and performance of watershed models.

    Science.gov (United States)

    Yen, Haw; Bailey, Ryan T; Arabi, Mazdak; Ahmadi, Mehdi; White, Michael J; Arnold, Jeffrey G

    2014-09-01

    Watershed models typically are evaluated solely through comparison of in-stream water and nutrient fluxes with measured data using established performance criteria, whereas processes and responses within the interior of the watershed that govern these global fluxes often are neglected. Due to the large number of parameters at the disposal of these models, circumstances may arise in which excellent global results are achieved using inaccurate magnitudes of these "intra-watershed" responses. When used for scenario analysis, a given model hence may inaccurately predict the global, in-stream effect of implementing land-use practices at the interior of the watershed. In this study, data regarding internal watershed behavior are used to constrain parameter estimation to maintain realistic intra-watershed responses while also matching available in-stream monitoring data. The methodology is demonstrated for the Eagle Creek Watershed in central Indiana. Streamflow and nitrate (NO) loading are used as global in-stream comparisons, with two process responses, the annual mass of denitrification and the ratio of NO losses from subsurface and surface flow, used to constrain parameter estimation. Results show that imposing these constraints not only yields realistic internal watershed behavior but also provides good in-stream comparisons. Results further demonstrate that in the absence of incorporating intra-watershed constraints, evaluation of nutrient abatement strategies could be misleading, even though typical performance criteria are satisfied. Incorporating intra-watershed responses yields a watershed model that more accurately represents the observed behavior of the system and hence a tool that can be used with confidence in scenario evaluation. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  10. The scaling of economic and performance parameters of DT and advanced fuel fusion reactors

    International Nuclear Information System (INIS)

    Roth, J.R.

    1983-01-01

    In this study, the plasma stability index beta and the fusion power density in the plasma were treated as independent variables to determine how they influenced three economic performance parameters of fusion reactors burning the DT and four advanced fusion fuel cycles. The economic/performance parameters included the total power produced per unit length of reactor; the mass per unit length, and the specific mass in kilograms/kilowatt. The scaling of these parameters with beta and fusion power density was examined for a common set of engineering assumptions on the allowable wall loading limits, the maximum magnetic field existing in the plasma, average blanket mass density, etc. It was found that the power per unit length decreased as the plasma power density and beta increased. This is a consequence of the fact that the first wall is a bottleneck in the energy flow from the plasma to the generating equipment, and the wall power flux will exceed wall loading limits if the plasma radius exceeds a critical value. If one wished to build an engineering test reactor which produced a burning plasma at the lowest possible initial cost, and without regard to whether such a reactor would ultimately produce the cheapest power, then one would minimize the mass per unit length. The mass per unit length decreases with increasing plasma power density and beta, with the DT reaction being the most expensive at a fixed plasma power density (because of its thicker blanket), and the least expensive at a fixed value of beta, at least up to values of beta of 50%. The specific mass, in kg/kw, which is a rough measure of the cost of the power generated by the reactor, shows an opposite trend. It increases with increasing plasma power density and beta. At a given plasma power density and low beta, the DT reaction gives the lowest specific mass, but at a fixed beta above 10%, the advanced fuel cycles have the lowest specific mass

  11. Renal function affects absorbed dose to the kidneys and haematological toxicity during {sup 177}Lu-DOTATATE treatment

    Energy Technology Data Exchange (ETDEWEB)

    Svensson, Johanna; Berg, Gertrud [Sahlgrenska University Hospital, Department of Oncology, Goeteborg (Sweden); Waengberg, Bo [Sahlgrenska University Hospital, Department of Surgery, Goeteborg (Sweden); Larsson, Maria [University of Gothenburg, Department of Radiation Physics, Institute of Clinical Sciences, The Sahlgrenska Academy, Goeteborg (Sweden); Forssell-Aronsson, Eva; Bernhardt, Peter [University of Gothenburg, Department of Radiation Physics, Institute of Clinical Sciences, The Sahlgrenska Academy, Goeteborg (Sweden); Sahlgrenska University Hospital, Department of Medical Physics and Medical Bioengineering, Goeteborg (Sweden)

    2015-05-01

    Peptide receptor radionuclide therapy (PRRT) has become an important treatment option in the management of advanced neuroendocrine tumours. Long-lasting responses are reported for a majority of treated patients, with good tolerability and a favourable impact on quality of life. The treatment is usually limited by the cumulative absorbed dose to the kidneys, where the radiopharmaceutical is reabsorbed and retained, or by evident haematological toxicity. The aim of this study was to evaluate how renal function affects (1) absorbed dose to the kidneys, and (2) the development of haematological toxicity during PRRT treatment. The study included 51 patients with an advanced neuroendocrine tumour who received {sup 177}Lu-DOTATATE treatment during 2006 - 2011 at Sahlgrenska University Hospital in Gothenburg. An average activity of 7.5 GBq (3.5 - 8.2 GBq) was given at intervals of 6 - 8 weeks on one to five occasions. Patient baseline characteristics according to renal and bone marrow function, tumour burden and medical history including prior treatment were recorded. Renal and bone marrow function were then monitored during treatment. Renal dosimetry was performed according to the conjugate view method, and the residence time for the radiopharmaceutical in the whole body was calculated. A significant correlation between inferior renal function before treatment and higher received renal absorbed dose per administered activity was found (p < 0.01). Patients with inferior renal function also experienced a higher grade of haematological toxicity during treatment (p = 0.01). The residence time of {sup 177}Lu in the whole body (range 0.89 - 3.0 days) was correlated with grade of haematological toxicity (p = 0.04) but not with renal absorbed dose (p = 0.53). Patients with inferior renal function were exposed to higher renal absorbed dose per administered activity and developed a higher grade of haematological toxicity during {sup 177}Lu-DOTATATE treatment. The study confirms the

  12. The Perspectives of Haematological Cancer Patients on Tissue Banking.

    Science.gov (United States)

    Turon, Heidi; Waller, Amy; Clinton-McHarg, Tara; Boyes, Allison; Fleming, Jennifer; Marlton, Paula; Harrison, Simon J; Sanson-Fisher, Rob

    2016-01-01

    A high level of support for tissue banking has been identified amongst both the general public and patients. However, much debate remains about the regulatory framework of tissue banks. This study explored the views of haematological cancer patients regarding tissue banking and how tissue banks should operate. Haematological cancer patients from three outpatient clinics in Australia completed a questionnaire examining their preferences for tissue banking as well as items about their sociodemographic characteristics, disease and treatment history. The majority of participants (95%) reported being willing to allow their leftover tissue to be used for medical research. Three quarters (76%) supported the idea of their medical record being linked to their tissue sample, and 77% preferred a blanket (one-off) consent model for future research use of their tissue sample. Only 57 (27%) participants had been asked to give a tissue sample for research, 98% of whom gave permission. The majority of haematological cancer patients are willing to donate their leftover tissue to a tissue bank and have their medical records linked to tissue samples and prefer a one-off consent process. These novel data from potential donors inform the debate about how tissue banks might operate. Strategic Research Partnership Grant from the Cancer Council NSW to the Newcastle Cancer Control Collaborative (New-3C) and infrastructure funding from the Hunter Medical Research Institute (HMRI). A.W. is supported by an Australian Research Council DECRA fellowship (DE150101262). T.C.M. was supported by a Leukaemia Foundation of Queensland Post-Doctoral Fellowship. A.B. is supported by National Health and Medical Research Council (APP1073317) and Cancer Institute NSW (13/ECF/1-37) Early Career Fellowships.

  13. Pulmonary aspergillosis in immunosuppressed patients with haematological malignancies.

    Science.gov (United States)

    Spearing, R L; Pamphilon, D H; Prentice, A G

    1986-06-01

    Invasive pulmonary aspergillosis as a cause of mortality and morbidity in patients with haematological malignancies is becoming more common. Predisposing factors are powerful immunosuppressive chemotherapy, neutropenia and synergistic combinations of antibiotics of great potency and wide spectrum of activity. Clinical and radiological signs are heterogeneous, sometimes misleading and often absent. Treatment is often empirical on suspicion alone. Amphotericin B is the only effective drug but it has marked toxicity, mainly renal. Infection is usually fatal without adequate treatment. This paper describes eight cases of invasive pulmonary aspergillosis seen in one centre in two years, reviews the literature and assesses associated problems.

  14. Preferred and actual place of death in haematological malignancy.

    Science.gov (United States)

    Howell, D A; Wang, H I; Roman, E; Smith, A G; Patmore, R; Johnson, M J; Garry, A; Howard, M

    2017-06-01

    Home is considered the preferred place of death for many, but patients with haematological malignancies (leukaemias, lymphomas and myeloma) die in hospital more often than those with other cancers and the reasons for this are not wholly understood. We examined preferred and actual place of death among people with these diseases. The study is embedded within an established population-based cohort of patients with haematological malignancies. All patients diagnosed at two of the largest hospitals in the study area between May 2005 and April 2008 with acute myeloid leukaemia, diffuse large B-cell lymphoma or myeloma, who died before May 2010 were included. Data were obtained from medical records and routine linkage to national death records. 323 deceased patients were included. A total of 142 (44%) had discussed their preferred place of death; 45.8% wanted to die at home, 28.2% in hospital, 16.9% in a hospice, 5.6% in a nursing home and 3.5% were undecided; 63.4% of these died in their preferred place. Compared to patients with evidence of a discussion, those without were twice as likely to have died within a month of diagnosis (14.8% vs 29.8%). Overall, 240 patients died in hospital; those without a discussion were significantly more likely to die in hospital than those who had (p≤0.0001). Of those dying in hospital, 90% and 75.8% received haematology clinical input in the 30 and 7 days before death, respectively, and 40.8% died in haematology areas. Many patients discussed their preferred place of death, but a substantial proportion did not and hospital deaths were common in this latter group. There is scope to improve practice, particularly among those dying soon after diagnosis. We found evidence that some people opted to die in hospital; the extent to which this compares with other cancers is of interest. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  15. Age-associated and breed-associated variations in haematological and biochemical variables in young labrador retriever and miniature schnauzer dogs.

    Science.gov (United States)

    Brenten, Thomas; Morris, Penelope J; Salt, Carina; Raila, Jens; Kohn, Barbara; Schweigert, Florian J; Zentek, Jürgen

    2016-01-01

    Breed, sex and age effects on haematological and biochemical variables were investigated in 24 labrador retriever and 25 miniature schnauzer dogs during the first year of life. Blood samples were taken regularly between weeks 8 and 52. White blood cell and red blood cell counts, haemoglobin concentration, haematocrit, mean cell volume, mean cell haemoglobin, mean cell haemoglobin concentration, platelet count as well as total protein, albumin, calcium, phosphate, alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, glutamate dehydrogenase, total cholesterol, triglycerides, creatine and urea were evaluated. For all haematological and biochemical parameters, there were significant effects of age on test results. Statistically significant effects for breed and the breed×age interaction on test results were observed for most of the parameters with the exception of haemoglobin. Variations in test results illustrate growth related alterations in body tissue and metabolism leading to dynamic and marked changes in haematological and biochemical parameters, which have to be considered for the interpretation of clinical data obtained from dogs in the first year of life.

  16. Effects of PEMFC operating parameters on the performance of an integrated ethanol processor

    Energy Technology Data Exchange (ETDEWEB)

    Francesconi, Javier A.; Mussati, Miguel C.; Aguirre, Pio A. [INGAR Instituto de Desarrollo y Diseno (CONICET-UTN), Avellaneda 3657, CP:S3002GJC, Santa Fe (Argentina)

    2010-06-15

    In this paper the performance of a complete fuel cell system processing ethanol fuel has been analyzed as a function of the main fuel cell operating parameters. The fuel processor is based on the steam reforming process, followed by high- and low-temperature shift reactors, and carbon monoxide preferential oxidation reactor, which are coupled to a polymeric fuel cell (PEMFC). The goal was to analyze and improve the fuel cell system performance by simulation techniques. PEMFC operation has been analyzed using an available parametric model, which was implemented within HYSYS environment software. Pinch Analysis concepts were used to investigate the process energy integration and determine the maximum efficiency minimizing ethanol consumption. The system performance was analyzed for the SR-12 Modular PEM Generator, the Ballard Mark V fuel cell and the BCS 500 W stack. The net system efficiency is dependent on the required power demand. Efficiency values higher than 50% at low loads and less than 30% at high power demands are computed. In addition, the effect of fuel cell temperature, pressure and hydrogen utilization was analyzed. The trade-off between the reformer yield and the fuel cell performance defines the optimal operation pressure. The cell temperature determines operating zones where the water, involved in the reforming reactions, can be produced or demanded. (author)

  17. The sublethal effects of copper and lead on the haematology and ...

    African Journals Online (AJOL)

    Toxicity bioassays were conducted on groovy mullet, Liza dumerili, using copper and lead, in order to assess how these metals affected their blood haematology and acid-base balance. Short-term (96 hours) exposure to lead caused significantly more haematological response [PCO2] than copper, when compared to the ...

  18. Perceived need for information of patients with haematological malignancies: a literature review

    NARCIS (Netherlands)

    Rood, J.A.J.; Eeltink, C.M.; van Zuuren, F.J.; Verdonck-de Leeuw, I.M.; Huijgens, P.C.

    2015-01-01

    Aims and objectives: To provide insight into the perceived need for information of patients with haematological malignancies. Background: Providing timely and accurate information to patients diagnosed with a haematological malignancy is a challenge in clinical practice; treatment often has to start

  19. Perceived need for information of patients with haematological malignancies: a literature review.

    NARCIS (Netherlands)

    Rood, J.A.; Eeltink, C.M.; van Zuuren, F.J.; de Leeuw, I.M.; Huijgens, P.C.

    2015-01-01

    Aims and objectives: To provide insight into the perceived need for information of patients with haematological malignancies. Background: Providing timely and accurate information to patients diagnosed with a haematological malignancy is a challenge in clinical practice; treatment often has to start

  20. Optimization of Design Parameters and Operating Conditions of Electrochemical Capacitors for High Energy and Power Performance

    Science.gov (United States)

    Ike, Innocent S.; Sigalas, Iakovos; Iyuke, Sunny E.

    2017-03-01

    Theoretical expressions for performance parameters of different electrochemical capacitors (ECs) have been optimized by solving them using MATLAB scripts as well as via the MATLAB R2014a optimization toolbox. The performance of the different kinds of ECs under given conditions was compared using theoretical equations and simulations of various models based on the conditions of device components, using optimal values for the coefficient associated with the battery-kind material ( K BMopt) and the constant associated with the electrolyte material ( K Eopt), as well as our symmetric electric double-layer capacitor (EDLC) experimental data. Estimation of performance parameters was possible based on values for the mass ratio of electrodes, operating potential range ratio, and specific capacitance of electrolyte. The performance of asymmetric ECs with suitable electrode mass and operating potential range ratios using aqueous or organic electrolyte at appropriate operating potential range and specific capacitance was 2.2 and 5.56 times greater, respectively, than for the symmetric EDLC and asymmetric EC using the same aqueous electrolyte, respectively. This enhancement was accompanied by reduced cell mass and volume. Also, the storable and deliverable energies of the asymmetric EC with suitable electrode mass and operating potential range ratios using the proper organic electrolyte were 12.9 times greater than those of the symmetric EDLC using aqueous electrolyte, again with reduced cell mass and volume. The storable energy, energy density, and power density of the asymmetric EDLC with suitable electrode mass and operating potential range ratios using the proper organic electrolyte were 5.56 times higher than for a similar symmetric EDLC using aqueous electrolyte, with cell mass and volume reduced by a factor of 1.77. Also, the asymmetric EDLC with the same type of electrode and suitable electrode mass ratio, working potential range ratio, and proper organic electrolyte

  1. Effects of shape and stroke parameters on the propulsion performance of an axisymmetric swimmer.

    Science.gov (United States)

    Peng, Jifeng; Alben, Silas

    2012-03-01

    In nature, there exists a special group of aquatic animals which have an axisymmetric body and whose primary swimming mechanism is to use periodic body contractions to generate vortex rings in the surrounding fluid. Using jellyfish medusae as an example, this study develops a mathematical model of body kinematics of an axisymmetric swimmer and uses a computational approach to investigate the induced vortex wakes. Wake characteristics are identified for swimmers using jet propulsion and rowing, two mechanisms identified in previous studies of medusan propulsion. The parameter space of body kinematics is explored through four quantities: a measure of body shape, stroke amplitude, the ratio between body contraction duration and extension duration, and the pulsing frequency. The effects of these parameters on thrust, input power requirement and circulation production are quantified. Two metrics, cruising speed and energy cost of locomotion, are used to evaluate the propulsion performance. The study finds that a more prolate-shaped swimmer with larger stroke amplitudes is able to swim faster, but its cost of locomotion is also higher. In contrast, a more oblate-shaped swimmer with smaller stroke amplitudes uses less energy for its locomotion, but swims more slowly. Compared with symmetric strokes with equal durations of contraction and extension, faster bell contractions increase the swimming speed whereas faster bell extensions decrease it, but both require a larger energy input. This study shows that besides the well-studied correlations between medusan body shape and locomotion, stroke variables also affect the propulsion performance. It provides a framework for comparing the propulsion performance of axisymmetric swimmers based on their body kinematics when it is difficult to measure and analyze their wakes empirically. The knowledge from this study is also useful for the design of robotic swimmers that use axisymmetric body contractions for propulsion.

  2. Effects of shape and stroke parameters on the propulsion performance of an axisymmetric swimmer

    International Nuclear Information System (INIS)

    Peng Jifeng; Alben, Silas

    2012-01-01

    In nature, there exists a special group of aquatic animals which have an axisymmetric body and whose primary swimming mechanism is to use periodic body contractions to generate vortex rings in the surrounding fluid. Using jellyfish medusae as an example, this study develops a mathematical model of body kinematics of an axisymmetric swimmer and uses a computational approach to investigate the induced vortex wakes. Wake characteristics are identified for swimmers using jet propulsion and rowing, two mechanisms identified in previous studies of medusan propulsion. The parameter space of body kinematics is explored through four quantities: a measure of body shape, stroke amplitude, the ratio between body contraction duration and extension duration, and the pulsing frequency. The effects of these parameters on thrust, input power requirement and circulation production are quantified. Two metrics, cruising speed and energy cost of locomotion, are used to evaluate the propulsion performance. The study finds that a more prolate-shaped swimmer with larger stroke amplitudes is able to swim faster, but its cost of locomotion is also higher. In contrast, a more oblate-shaped swimmer with smaller stroke amplitudes uses less energy for its locomotion, but swims more slowly. Compared with symmetric strokes with equal durations of contraction and extension, faster bell contractions increase the swimming speed whereas faster bell extensions decrease it, but both require a larger energy input. This study shows that besides the well-studied correlations between medusan body shape and locomotion, stroke variables also affect the propulsion performance. It provides a framework for comparing the propulsion performance of axisymmetric swimmers based on their body kinematics when it is difficult to measure and analyze their wakes empirically. The knowledge from this study is also useful for the design of robotic swimmers that use axisymmetric body contractions for propulsion. (paper)

  3. Influence of electrical resistivity and machining parameters on electrical discharge machining performance of engineering ceramics.

    Science.gov (United States)

    Ji, Renjie; Liu, Yonghong; Diao, Ruiqiang; Xu, Chenchen; Li, Xiaopeng; Cai, Baoping; Zhang, Yanzhen

    2014-01-01

    Engineering ceramics have been widely used in modern industry for their excellent physical and mechanical properties, and they are difficult to machine owing to their high hardness and brittleness. Electrical discharge machining (EDM) is the appropriate process for machining engineering ceramics provided they are electrically conducting. However, the electrical resistivity of the popular engineering ceramics is higher, and there has been no research on the relationship between the EDM parameters and the electrical resistivity of the engineering ceramics. This paper investigates the effects of the electrical resistivity and EDM parameters such as tool polarity, pulse interval, and electrode material, on the ZnO/Al2O3 ceramic's EDM performance, in terms of the material removal rate (MRR), electrode wear ratio (EWR), and surface roughness (SR). The results show that the electrical resistivity and the EDM parameters have the great influence on the EDM performance. The ZnO/Al2O3 ceramic with the electrical resistivity up to 3410 Ω·cm can be effectively machined by EDM with the copper electrode, the negative tool polarity, and the shorter pulse interval. Under most machining conditions, the MRR increases, and the SR decreases with the decrease of electrical resistivity. Moreover, the tool polarity, and pulse interval affect the EWR, respectively, and the electrical resistivity and electrode material have a combined effect on the EWR. Furthermore, the EDM performance of ZnO/Al2O3 ceramic with the electrical resistivity higher than 687 Ω·cm is obviously different from that with the electrical resistivity lower than 687 Ω·cm, when the electrode material changes. The microstructure character analysis of the machined ZnO/Al2O3 ceramic surface shows that the ZnO/Al2O3 ceramic is removed by melting, evaporation and thermal spalling, and the material from the working fluid and the graphite electrode can transfer to the workpiece surface during electrical discharge

  4. Effect of dietary protein sources on production performance, egg quality, and plasma parameters of laying hens

    Directory of Open Access Journals (Sweden)

    Xiaocui Wang

    2017-03-01

    Full Text Available Objective This study was conducted to evaluate the effects of dietary protein sources (soybean meal, SBM; low-gossypol cottonseed meal, LCSM; double-zero rapeseed meal, DRM on laying performance, egg quality, and plasma parameters of laying hens. Methods A total of 432 32-wk-old laying hens were randomly divided into 6 treatments with 6 replicates of 12 birds each. The birds were fed diets containing SBM, LCSM100, or DRM100 individually or in combination with an equal amount of crude protein (CP (LCSM50, DRM50, and LCSM50-DRM50. The experimental diets, which were isocaloric (metabolizable energy, 11.11 MJ/kg and isonitrogenous (CP, 16.5%, had similar digestible amino acid profile. The feeding trial lasted 12 weeks. Results The daily egg mass was decreased in the LCSM100 and LCSM50-DRM50 groups (p0.05 and showed increased yolk color at the end of the trial (p0.05. Conclusion Together, our results suggest that the LCSM100 or DRM100 diets may produce the adverse effects on laying performance and egg quality after feeding for 8 more weeks. The 100.0 g/kg LCSM diet or the148.7 g/kg DRM diet has no adverse effects on laying performance and egg quality.

  5. Stack Parameters Effect on the Performance of Anharmonic Resonator Thermoacoustic Heat Engine

    KAUST Repository

    Nouh, Mostafa A.

    2014-01-01

    A thermoacoustic heat engine (TAHE) converts heat into acoustic power with no moving parts. It exhibits several advantages over traditional engines, such as simple design, stable functionality, and environment-friendly working gas. In order to further improve the performance of TAHE, stack parameters need to be optimized. Stack\\'s position, length and plate spacing are the three main parameters that have been investigated in this study. Stack\\'s position dictates both the efficiency and the maximum produced acoustic power of the heat engine. Positioning the stack closer to the pressure anti-node might ensure high efficiency on the expense of the maximum produced acoustic power. It is noticed that the TAHE efficiency can further be improved by spacing the plates of the stack at a value of 2.4 of the thermal penetration depth, δk . Changes in the stack length will not affect the efficiency much as long as the temperature gradient across the stack, as a ratio of the critical temperature gradient ψ is more than 1. Upon interpreting the effect of these variations, attempts are made towards reaching the engine\\'s most powerful operating point.

  6. Thermal performance analysis and optimum design parameters of heat exchanger having perforated pin fins

    International Nuclear Information System (INIS)

    Sahin, Bayram; Demir, Alparslan

    2008-01-01

    This paper reports the heat transfer enhancement and corresponding pressure drop over a flat surface equipped with circular cross section perforated pin fins in a rectangular channel. The channel had a cross section area of 100-250 mm 2 . The experiments covered the following ranges: Reynolds number 13500-42,000, clearance ratio (C/H) 0, 0.33 and 1 and interfin spacing ratio (S y /D) 1.208, 1.524, 1.944 and 3.417. Correlation equations were developed for the heat transfer, friction factor and enhancement efficiency. The experimental results showed that the use of circular cross section pin fins may lead to heat transfer enhancement. Enhancement efficiencies varied between 1.4 and 2.6 depending on clearance ratio and interfin spacing ratio. Using a Taguchi experimental design method, optimum design parameters and their levels were investigated. Nusselt number and friction factor were considered as performance parameters. An L 9 (3 3 ) orthogonal array was selected as an experimental plan. First of all, each goal was optimized separately. Then, all the goals were optimized together, considering the priority of the goals, and the optimum results were found to be Reynolds number of 42,000, fin height of 50 mm and streamwise distance between fins of 51 mm

  7. Stack Parameters Effect on the Performance of Anharmonic Resonator Thermoacoustic Heat Engine

    KAUST Repository

    Nouh, Mostafa A.; Arafa, Nadim M.; Abdel-Rahman, Ehab

    2014-01-01

    A thermoacoustic heat engine (TAHE) converts heat into acoustic power with no moving parts. It exhibits several advantages over traditional engines, such as simple design, stable functionality, and environment-friendly working gas. In order to further improve the performance of TAHE, stack parameters need to be optimized. Stack's position, length and plate spacing are the three main parameters that have been investigated in this study. Stack's position dictates both the efficiency and the maximum produced acoustic power of the heat engine. Positioning the stack closer to the pressure anti-node might ensure high efficiency on the expense of the maximum produced acoustic power. It is noticed that the TAHE efficiency can further be improved by spacing the plates of the stack at a value of 2.4 of the thermal penetration depth, δk . Changes in the stack length will not affect the efficiency much as long as the temperature gradient across the stack, as a ratio of the critical temperature gradient ψ is more than 1. Upon interpreting the effect of these variations, attempts are made towards reaching the engine's most powerful operating point.

  8. A study of the effects of collector and environment parameters on the performance of a solar powered solid adsorption refrigerator

    International Nuclear Information System (INIS)

    Li, M.; Wang, R.Z.

    2002-01-01

    Based on the heat and mass transfer model validated by experiment, the performance of the plate solar ice-maker is analyzed systemically with the opinion of two-type characteristic parameters, which includes parametric effects of adsorbent bed of solar ice-maker and outer parameters referring to circumstance. A large number of simulations were undertaken to test the performance of the refrigerator for various collector design parameters and environmental parameters. These works are beneficial to further study the optimization design of a solar cooling system. (Author)

  9. Analysis of performance and device parameters of CIGS PV modules deployed outdoors

    Energy Technology Data Exchange (ETDEWEB)

    Radue, C. [Physics Department, P.O. Box 77000, Nelson Mandela Metropolitan University, Port Elizabeth, 6031 (South Africa)], E-mail: chantelle.radue@nmmu.ac.za; Dyk, E.E. van; Macabebe, E.Q. [Physics Department, P.O. Box 77000, Nelson Mandela Metropolitan University, Port Elizabeth, 6031 (South Africa)

    2009-02-02

    Two 20 W copper indium gallium diselenide photovoltaic modules were subjected to a thorough indoor assessment procedure, followed by outdoor deployment at the Nelson Mandela Metropolitan University as part of an ongoing study. The initial indoor measurement of maximum power output (P{sub MAX}) of one of the modules was considerably higher than the manufacturer's rating (E.E. van Dyk, C. Radue and A.R. Gxasheka, Thin Solid Films 515 (2007) 6196). The modules were deployed on a dual-axis solar tracker and current-voltage characteristics were obtained weekly. In addition to the normal PV parameters of short-circuit current, open-circuit voltage, P{sub MAX}, fill factor and efficiency, shunt and series resistances were also monitored. The performances of the two modules are compared and analyzed and the results presented in this paper.

  10. Combination for differential and integral data: Sensitivity and uncertainty analysis of reactor performance parameters

    International Nuclear Information System (INIS)

    Marable, J.H.; de Saussure, G.; Weisbin, C.R.

    1982-01-01

    This chapter attempts to show how the various types of data presented and discussed in previous chapters can be combined and applied to the calculation of performance parameters of a reactor design model. Discusses derivation of least-squares adjustment; input data to the adjustment; the results of adjustment; and application to an LMFBR. Demonstrates that the least-squares formulae represent a logical, well-founded method for combining the results of integral and differential experiments. Includes calculational bias factors and their uncertainties. Concludes that the adjustment technique is a valuable tool, and that significant progress has been made with respect to its development and its applications. Recommends further work on the evaluation of covariance files, especially for calculational biases, and the inclusion of specific shielding factors as variables to be adjusted. The appendix features a calculation whose goal is to find the form of the projection operator which projects perpendicular to the calculational manifold

  11. Analysis of performance and device parameters of CIGS PV modules deployed outdoors

    International Nuclear Information System (INIS)

    Radue, C.; Dyk, E.E. van; Macabebe, E.Q.

    2009-01-01

    Two 20 W copper indium gallium diselenide photovoltaic modules were subjected to a thorough indoor assessment procedure, followed by outdoor deployment at the Nelson Mandela Metropolitan University as part of an ongoing study. The initial indoor measurement of maximum power output (P MAX ) of one of the modules was considerably higher than the manufacturer's rating (E.E. van Dyk, C. Radue and A.R. Gxasheka, Thin Solid Films 515 (2007) 6196). The modules were deployed on a dual-axis solar tracker and current-voltage characteristics were obtained weekly. In addition to the normal PV parameters of short-circuit current, open-circuit voltage, P MAX , fill factor and efficiency, shunt and series resistances were also monitored. The performances of the two modules are compared and analyzed and the results presented in this paper

  12. Mesh parameters influence on transparent and active antennas performance at microwaves

    Directory of Open Access Journals (Sweden)

    Alexis Martin

    2017-08-01

    Full Text Available Optically transparent and active square loop coplanar antennas operating in X-band are investigated in this letter. The frequency tunability is provided by a surface mounted beam-lead varactor with micrometric size, thereby no-visible to the naked eye. The influence of the metal mesh parameters on the sheet resistance (from 0.05 Ω/sq to 0.54 Ω/sq, the optical transparency (from 66% to 89% and the microwave performance (return loss, resonance frequency, radiation pattern and gain of such antennas is evaluated, compared with those of an opaque counterpart, and finally discussed. This study paves the way of their promising implementation on new surfaces, namely building and car windows for future wireless communications systems.

  13. Effect of design parameters on performance of a top fired natural gas reformer

    International Nuclear Information System (INIS)

    Ebrahimi, Hadi; Mohammadzadeh, Jafar S. Soltan; Zamaniyan, Akbar; Shayegh, Flora

    2008-01-01

    A three-dimensional zone method was applied to an industrial fired heater of methane steam reforming reactor. Radiation heat transfer from all gases and surfaces inside the furnace was considered. Results from previous work and data of an industrial top fired furnace were used to validate the model. A maximum temperature in external reaction tube skin was obtained at about one third of the reactor length from top in the industrial furnace. Effect of important parameters such as emissivity, extinction coefficient, heat release pattern and flame angle on performance of the fired heater are presented. It was found that decreasing the extinction coefficients of combustion gases by 25% (from about 0.20 to 0.15) caused 2.6% rise in temperature of heat sink surfaces. It was demonstrated that the three-dimensional zone method developed in this work is simple, easy and flexible for modeling and simulation of the fired heaters

  14. Key performance indicators for stroke from the Ministry of Health of Brazil: benchmarking and indicator parameters

    Directory of Open Access Journals (Sweden)

    Marcos C Lange

    Full Text Available ABSTRACT The present study aimed to analyze the stroke units in two centers for the key performance indicators (KPIs required by the Ministry of Health in Brazil. Methods All 16 KPIs were analyzed, including the percentage of patients admitted to the stroke unit, venous thromboembolism prophylaxis in the first 48 hours after admission, pneumonia and hospital mortality due to stroke, and hospital discharge on antithrombotic therapy in patients without cardioembolic mechanism. Results Both centers admitted over 80% of the patients in their stroke unit. The incidence of venous thromboembolism prophylaxis was > 85%, that of in-hospital pneumonia was 70%. Conclusion Our results suggest using the parameters of all of the 16 KPIs required by the Ministry of Health of Brazil, and the present results for the two stroke units for future benchmarking.

  15. Design of Parameter Independent, High Performance Sensorless Controllers for Permanent Magnet Synchronous Machines

    DEFF Research Database (Denmark)

    Xie, Ge

    . The transient fluctuation of the estimated rotor position error is around 20 degrees with a step load torque change from 0% to 100% of the rated torque. The position error in steady state is within ±2 electrical degrees for the best case. The proposed method may also be used for e.g. online machine parameter......The Permanent Magnet Synchronous Machine (PMSM) has become an attractive candidate for various industrial applications due to its high efficiency and torque density. In the PMSM drive system, simple and robust control methods play an important role in achieving satisfactory drive performances....... For reducing the cost and increasing the reliability of the drive system, eliminating the mechanical sensor brings a lot advantages to the PMSM drive system. Therefore, sensorless control was developed and has been increasingly used in different PMSM drive systems in the last 20 years. However, machine...

  16. Advances in three-dimensional field analysis and evaluation of performance parameters of electrical machines

    Science.gov (United States)

    Sivasubramaniam, Kiruba

    This thesis makes advances in three dimensional finite element analysis of electrical machines and the quantification of their parameters and performance. The principal objectives of the thesis are: (1)the development of a stable and accurate method of nonlinear three-dimensional field computation and application to electrical machinery and devices; and (2)improvement in the accuracy of determination of performance parameters, particularly forces and torque computed from finite elements. Contributions are made in two general areas: a more efficient formulation for three dimensional finite element analysis which saves time and improves accuracy, and new post-processing techniques to calculate flux density values from a given finite element solution. A novel three-dimensional magnetostatic solution based on a modified scalar potential method is implemented. This method has significant advantages over the traditional total scalar, reduced scalar or vector potential methods. The new method is applied to a 3D geometry of an iron core inductor and a permanent magnet motor. The results obtained are compared with those obtained from traditional methods, in terms of accuracy and speed of computation. A technique which has been observed to improve force computation in two dimensional analysis using a local solution of Laplace's equation in the airgap of machines is investigated and a similar method is implemented in the three dimensional analysis of electromagnetic devices. A new integral formulation to improve force calculation from a smoother flux-density profile is also explored and implemented. Comparisons are made and conclusions drawn as to how much improvement is obtained and at what cost. This thesis also demonstrates the use of finite element analysis to analyze torque ripples due to rotor eccentricity in permanent magnet BLDC motors. A new method for analyzing torque harmonics based on data obtained from a time stepping finite element analysis of the machine is

  17. Synergistic improvement of gas sensing performance by micro-gravimetrically extracted kinetic/thermodynamic parameters

    International Nuclear Information System (INIS)

    Guo, Shuanbao; Xu, Pengcheng; Yu, Haitao; Cheng, Zhenxing; Li, Xinxin

    2015-01-01

    Highlights: • Sensing material can be comprehensively optimized by using gravimetric cantilever. • Kinetic-thermodynamic model parameters are quantitatively extracted by experiment • Sensing-material performance is synergistically optimized by extracted parameters. - Abstract: A novel method is explored for comprehensive design/optimization of organophosphorus sensing material, which is loaded on mass-type microcantilever sensor. Conventionally, by directly observing the gas sensing response, it is difficult to build quantitative relationship with the intrinsic structure of the material. To break through this difficulty, resonant cantilever is employed as gravimetric tool to implement molecule adsorption experiment. Based on the sensing data, key kinetic/thermodynamic parameters of the material to the molecule, including adsorption heat −ΔH°, adsorption/desorption rate constants K a and K d , active-site number per unit mass N′ and surface coverage θ, can be quantitatively extracted according to physical–chemistry theories. With gaseous DMMP (simulant of organophosphorus agents) as sensing target, the optimization route for three sensing materials is successfully demonstrated. Firstly, a hyper-branched polymer is evaluated. Though suffering low sensitivity due to insufficient N′, the bis(4-hydroxyphenyl)-hexafluoropropane (BHPF) sensing-group exhibits satisfactory reproducibility due to appropriate −ΔH°. To achieve more sensing-sites, KIT-5 mesoporous-silica with higher surface-area is assessed, resulting in good sensitivity but too high −ΔH° that brings poor repeatability. After comprehensive consideration, the confirmed BHPF sensing-group is grafted on the KIT-5 carrier to form an optimized DMMP sensing nanomaterial. Experimental results indicate that, featuring appropriate kinetic/thermodynamic parameters of −ΔH°, K a , K d , N′ and θ, the BHPF-functionalized KIT-5 mesoporous silica exhibits synergistic improvement among

  18. Breed-Specific Haematologic Reference Values in Adult Turkeys (Meleagris gallopavo in the Humid Tropics of Nigeria

    Directory of Open Access Journals (Sweden)

    Daniel-Igwe G.

    2017-03-01

    Full Text Available One hundred (50 males and 50 females B-not strain indigenous turkeys, Meleagris gallopavo, were used to determine the reference values for their haematological parameters. The turkeys were housed in the poultry unit and jugular venepunctures were used to collect their blood. The haematological parameters were determined using standard procedures. The mean values of: the packed cell volume (PCV; 37.29 ± 0.37 %, red blood cell (RBC counts (2.50 ± 0.44 × 106.µl−1, haemoglobin concentration (Hbc; 10.89 ± 0.34 g.dl−1, mean corpuscular volume (MCV; 150.63 ± 0.73 fl, mean corpuscular haemoglobin (MCH; 44.29 ± 1.78 pg, mean corpuscular haemoglobin concentration (MCHC; 29.10 ± 0.73 g.dl−1, and white blood cell (WBC counts (12.41 ± 0.83 × 103 µl−1 were determined. No significant differences were found between the male and female B-not strain turkeys in this study. The results will help in the interpretation of cases of disease when there are variations in the values and serve as baseline data for B-not strain of turkeys in the humid tropics.

  19. PERFORMANCE ANALYSIS OF OPTICAL CDMA SYSTEM USING VC CODE FAMILY UNDER VARIOUS OPTICAL PARAMETERS

    Directory of Open Access Journals (Sweden)

    HASSAN YOUSIF AHMED

    2012-06-01

    Full Text Available The intent of this paper is to study the performance of spectral-amplitude coding optical code-division multiple-access (OCDMA systems using Vector Combinatorial (VC code under various optical parameters. This code can be constructed by an algebraic way based on Euclidian vectors for any positive integer number. One of the important properties of this code is that the maximum cross-correlation is always one which means that multi-user interference (MUI and phase induced intensity noise are reduced. Transmitter and receiver structures based on unchirped fiber Bragg grating (FBGs using VC code and taking into account effects of the intensity, shot and thermal noise sources is demonstrated. The impact of the fiber distance effects on bit error rate (BER is reported using a commercial optical systems simulator, virtual photonic instrument, VPITM. The VC code is compared mathematically with reported codes which use similar techniques. We analyzed and characterized the fiber link, received power, BER and channel spacing. The performance and optimization of VC code in SAC-OCDMA system is reported. By comparing the theoretical and simulation results taken from VPITM, we have demonstrated that, for a high number of users, even if data rate is higher, the effective power source is adequate when the VC is used. Also it is found that as the channel spacing width goes from very narrow to wider, the BER decreases, best performance occurs at a spacing bandwidth between 0.8 and 1 nm. We have shown that the SAC system utilizing VC code significantly improves the performance compared with the reported codes.

  20. Performance evaluation and parameter sensitivity of energy-harvesting shock absorbers on different vehicles

    Science.gov (United States)

    Guo, Sijing; Liu, Yilun; Xu, Lin; Guo, Xuexun; Zuo, Lei

    2016-07-01

    Traditional shock absorbers provide favourable ride comfort and road handling by dissipating the suspension vibration energy into heat waste. In order to harvest this dissipated energy and improve the vehicle fuel efficiency, many energy-harvesting shock absorbers (EHSAs) have been proposed in recent years. Among them, two types of EHSAs have attracted much attention. One is a traditional EHSA which converts the oscillatory vibration into bidirectional rotation using rack-pinion, ball-screw or other mechanisms. The other EHSA is equipped with a mechanical motion rectifier (MMR) that transforms the bidirectional vibration into unidirectional rotation. Hereinafter, they are referred to as NonMMR-EHSA and MMR-EHSA, respectively. This paper compares their performances with the corresponding traditional shock absorber by using closed-form analysis and numerical simulations on various types of vehicles, including passenger cars, buses and trucks. Results suggest that MMR-EHSA provides better ride performances than NonMMR-EHSA, and that MMR-EHSA is able to improve both the ride comfort and road handling simultaneously over the traditional shock absorber when installed on light-damped, heavy-duty vehicles. Additionally, the optimal parameters of MMR-EHSA are obtained for ride comfort. The optimal solutions ('Pareto-optimal solutions') are also obtained by considering the trade-off between ride comfort and road handling.

  1. Music in CrossFit®—Influence on Performance, Physiological, and Psychological Parameters

    Directory of Open Access Journals (Sweden)

    Gavin Brupbacher

    2014-01-01

    Full Text Available Gaining increasing popularity within the fitness sector, CrossFit® serves as an appealing and efficient high intensity training approach to develop strength and endurance on a functional level; and music is often utilized to produce ergogenic effects. The present randomized, controlled, crossover study aimed at investigating the effects of music vs. non-music on performance, physiological and psychological outcomes. Thirteen (age: 27.5, standard deviation (SD 6.2 years, healthy, moderately trained subjects performed four identical workouts over two weeks. The order of the four workouts (two with, and two without music, 20 min each was randomly assigned for each individual. Acute responses in work output, heart rate, blood lactate, rate of perceived exertion, perceived pain, and affective reaction were measured at the 5th, 10th, 15th, and 20th min during the training sessions. Training with music resulted in a significantly lower work output (460.3 repetitions, SD 98.1 vs. 497.8 repetitions, SD 103.7; p = 0.03. All other parameters did not differ between both music conditions. This is partly in line with previous findings that instead of providing ergogenic effects, applying music during CrossFit® may serve as a more distractive stimulus. Future studies should separate the influence of music on a more individual basis with larger sample sizes.

  2. Genetic parameters for type classification of Nelore cattle on central performance tests at pasture in Brazil.

    Science.gov (United States)

    Lima, Paulo Ricardo Martins; Paiva, Samuel Rezende; Cobuci, Jaime Araujo; Braccini Neto, José; Machado, Carlos Henrique Cavallari; McManus, Concepta

    2013-10-01

    The objective of this study was to characterize Nelore cattle on central performance tests in pasture, ranked by the visual classification method EPMURAS (structure, precocity, muscle, navel, breed, posture, and sexual characteristics), and to estimate genetic and phenotypic correlations between these parameters, including visual as well as production traits (initial and final weight on test, weight gain, and weight corrected for 550 days). The information used in the study was obtained on 21,032 Nelore bulls which were participants in the central performance test at pasture of the Brazilian Association for Zebu Breeders (ABCZ). Heritabilities obtained were from 0.19 to 0.50. Phenotypic correlations were positive from 0.70 to 0.97 between the weight traits, from 0.65 to 0.74 between visual characteristics, and from 0.29 to 0.47 between visual characteristics and weight traits. The genetic correlations were positive ranging from 0.80 to 0.98 between the characteristics of structure, precocity and musculature, from 0.13 to 0.64 between the growth characteristics, and from 0.41 to 0.97 between visual scores and weight gains. Heritability and genetic correlations indicate that the use of visual scores, along with the selection for growth characteristics, can bring positive results in selection of beef cattle for rearing on pasture.

  3. RELATIONSHIPS BETWEEN HEART RATE AND PHYSIOLOGICAL PARAMETERS OF PERFORMANCE IN TOP-LEVEL WATER POLO PLAYERS

    Directory of Open Access Journals (Sweden)

    O. Galy

    2014-07-01

    Full Text Available The aim of this study was to measure the heart rate (HR response of eight elite water polo players during the four 7-min quarters of the game and to check for relationships with the physiological parameters of performance ( ·VO2max, Th1vent, Th2vent. Each athlete performed a ·VO2max treadmill test and played a water polo game wearing a heart rate monitor. The game fatigue index was calculated as the ratio of the fourth-quarter HR to the first-quarter HR: HR4/HR1. The results showed a slight decrease in fourth-quarter HR compared with the first quarter, with the mean four-quarter HR equal to 79.9 ± 4.2% of HRmax. Stepwise multiple regression analysis showed ·VO2max to be the main explanatory factor of game intensity, i.e. game HR expressed in %HRreserve (R=0.88, P<0.01. We observed that higher aerobic capacity resulted in higher game intensity. We also observed a decrease in the playing intensity in the fourth quarter compared with the first, likely due to very high game involvement. We concluded that high aerobic capacity seems necessary to ensure high game intensity in water polo. This suggests that coaches should encourage their athletes to reach a minimum level of ·VO2max and that HR monitoring could be of great interest in the control of water polo training sessions.

  4. Effects of egg storage on hatchability, chick quality, performance and immunocompetence parameters of broiler chickens.

    Science.gov (United States)

    Goliomytis, Michael; Tsipouzian, Theofania; Hager-Theodorides, Ariadne L

    2015-09-01

    Pre-incubation egg storage is a necessity for the poultry industry. This study evaluated the effects of pre-incubation storage length of broiler eggs on hatchability, 1-day-old chick quality, subsequent performance, and immunocompetence. To this end, a total of 360 hatching eggs were stored for 4, 12, or 16 d prior to incubation. Hatchability and chick quality were assessed at hatch, and growth performance and immunocompetence parameters were assessed during a 35 d rearing period. Hatchability of set and fertile eggs, and embryonic mortality, were not affected by egg storage. On the contrary, 1-day-old chick BW and length were linearly negatively correlated with egg storage length (P-linearegg weight prior to setting was unaffected, and corrected chick length was positively affected by storage length. One-day-old chick Tona score, navel quality, and post-hatch growth performance (BW at 7 and 35 d, cumulative feed intake, and feed conversion ratio at 35 d) were unaffected by egg storage (P, P-linear>0.05). Lymphoid organ weights at 2 and 35 d, the titre of maternal anti-NDV antibodies, most of the thymocyte subpopulations defined by CD3, CD4, and CD8 cell surface expression in the thymus of 2-d-old chicks, cellular responses to the PHA skin test, humoral responses to primary SRBC, and NDV immunizations were also not influenced by length of storage (P, P-linear>0.05). On the contrary, the length of egg storage was found to negatively influence the abundance of CD3+CD4-CD8- thymocytes that represent the majority of γδ-T cells in the thymus of 2-day-old chicks, as well as the humoral response to booster NDV immunization of the birds. In brief, pre-incubation storage of broiler hatching eggs for up to 16 d did not affect most developmental and growth parameters investigated, except for BW and length at hatch. Egg storage was found to suppress some aspects of the immunocompetence of the birds, particularly aspects of acquired immunity. © 2015 Poultry Science

  5. Reference haematological values for full term healthy newborns from rural sindh, pakistan

    International Nuclear Information System (INIS)

    Pasha, W.

    2015-01-01

    Normal values of complete blood counts show variation from region to region and between different ethnic groups. It is important to establish reference range for these values in our population for clinical use by our physicians. This descriptive cross sectional study aimed at establishing the normal reference values of complete blood counts in physically normal full term new borns of Panu Aqil, Rural Sind, Pakistan. Methods: The study was conducted at Combined Military Hospital, Panu Aqil Cantonment, from January 2010 to March 2011, on 316 term normal neonates selected on the basis of gestational age of 37 weeks or more with uneventful antenatal period. During the initial 12 hours of delivery, 2 ml Cord blood was collected in bottle containing tripotassium ethylene diamine tetra acetic acid (K3EDTA) as the anticoagulant and Complete blood counts were performed by Sysmex KX-21 automated haematology analyser. Blood films were prepared and stained by Leishman stain. Results: The haemoglobin was mean ± SD 15.4 ± 1.9 g/dL. The Mean Corpuscular Volume (MCV) was 103.4 ± 4.6 fL, while Mean Corpuscular haemoglobin (MCH) was 33.8 ± 1.6 pg. The Red cell Distribution Width-CV (RDW-CV) was 18.5 ± 1.8%. The total leukocyte count (TLC) was mean ± SD 13.7 ± 4.0*109 /L. The Absolute Neutrophil count (ANC) was mean+-SD 7.7 ± 3.0x109 /L. The Absolute Lymphocyte count (ALC) was mean+-SD 5.1 ± 1.8*109 /L. Platelet count was mean ± SD 285 ± 62x109 /L. Conclusion: Our values provide reference range for haematological values in healthy newborns of Panu Aqil, Rural Sindh, for clinical use by our physicians. (author)

  6. Effects of lighting and task parameters on visual acuity and performance

    Energy Technology Data Exchange (ETDEWEB)

    Halonen, L.

    1993-12-31

    Lighting and task parameters and their effects on visual acuity and visual performance are dealt with. The parameters studied are target contrast, target size and subject`s age; and also adaptation luminance, luminance ratio between task and its surrounding and temporal change in luminances are studied. Experiments were carried out to examine the effects of luminance and light spectrum on visual acuity. Young normally sighted, older and low vision people participated in the measurements. In the young and older subject groups the visual acuity remained unchanged at contrasts 0.93 and 0.63 at the luminance range of 15-630 cd/m{sub 2}. The results show that at contrasts 0.03-0.93 young and older subjects` visual acuity remained unchanged in the luminance range of 105-630 cd/m{sub 2}. In the low vision group, the changes in luminances between 25-860 cd/m{sub 2} did not have significant effects on visual acuity measured at high contrast 0.93, at low contrast, slight individual changes were found. The colour temperature of the light sources was altered between 2900-9500 K in the experiment. In the groups of the older, young and low vision subjects the light spectrum did not have significant effects on visual acuity, except for two retinitis pigmentosa subjects. On the basis of the visual acuity experiments, a three dimensional visual acuity model (VA-HUT) has been developed. The model predicts visual acuity as a function of luminance, target contrast and observer age. On the basis of visual acuity experiments visual acuity reserve values have been calculated for different text sizes

  7. Effect of fermented biogas residue on growth performance, serum biochemical parameters, and meat quality in pigs

    Directory of Open Access Journals (Sweden)

    Xiang Xu

    2017-10-01

    Full Text Available Objective This study investigated the effect of fermented biogas residue (FBR of wheat on the performance, serum biochemical parameters, and meat quality in pigs. Methods We selected 128 pigs (the mean initial body weight was 40.24±3.08 kg and randomly allocated them to 4 groups (1 control group and 3 treatment groups with 4 replicates per group and 8 pigs per pen in a randomized complete block design based on initial body weight and sex. The control group received a corn-soybean meal-based diet, the treatment group fed diets containing 5%, 10%, and 15% FBR, respectively (abbreviated as FBR5, FBR10, and FBR15, respectively. Every group received equivalent-energy and nitrogen diets. The test lasted 60 days and was divided into early and late stages. Blood and carcass samples were obtained on 60 d. Meat quality was collected from two pigs per pen. Results During the late stage, the average daily feed intake and average daily gain of the treatment groups was greater than that of the control group (p<0.05. During the entire experiment, the average daily gain of the treatment groups was higher than that of the control group (p<0.05. Fermented biomass residue did not significantly affect serum biochemical parameters or meat quality, but did affect amino acid profiles in pork. The contents of Asp, Arg, Tyr, Phe, Leu, Thr, Ser, Lys, Pro, Ala, essential amino acids, non-essential amino acids, and total amino acids in pork of FBR5 and FBR10 were greater than those of the control group (p<0.05. Conclusion These combined results suggest that feeding FBR could increase the average daily gain and average daily feed intake in pigs and the content of several flavor-promoting amino acids.

  8. Sensitivity analysis in oxidation ditch modelling: the effect of variations in stoichiometric, kinetic and operating parameters on the performance indices

    NARCIS (Netherlands)

    Abusam, A.A.A.; Keesman, K.J.; Straten, van G.; Spanjers, H.; Meinema, K.

    2001-01-01

    This paper demonstrates the application of the factorial sensitivity analysis methodology in studying the influence of variations in stoichiometric, kinetic and operating parameters on the performance indices of an oxidation ditch simulation model (benchmark). Factorial sensitivity analysis

  9. Predictive Performance of Echocardiographic Parameters for Cardiovascular Events Among Elderly Treated Hypertensive Patients.

    Science.gov (United States)

    Chowdhury, Enayet K; Jennings, Garry L R; Dewar, Elizabeth; Wing, Lindon M H; Reid, Christopher M

    2016-07-01

    Hypertension leads to cardiac structural and functional changes, commonly assessed by echocardiography. In this study, we assessed the predictive performance of different echocardiographic parameters including left ventricular hypertrophy (LVH) on future cardiovascular outcomes in elderly hypertensive patients without heart failure. Data from LVH substudy of the Second Australian National Blood Pressure trial were used. Echocardiograms were performed at entry into the study. Cardiovascular outcomes were identified over short term (median 4.2 years) and long term (median 10.9 years). LVH was defined using threshold values of LV mass (LVM) indexed to either body surface area (BSA) or height(2.7): >115/95g/m(2) (LVH-BSA(115/95)) or ≥49/45g/m(2.7) (LVH-ht(49/45)) in males/females, respectively, and ≥125g/m(2) (LVH-BSA(125)) or ≥51g/m(2.7) (LVH-ht(51)) for both sexes. In the 666 participants aged ≥65 years in this analysis, LVH prevalence at baseline was 33%-70% depending on definition; and after adjusting for potential risk factors, only LVH-BSA(115/95) predicted both short- and long-term cardiovascular outcomes. Participants having LVH-BSA(115/95) (69%) at baseline had twice the risk of having any first cardiovascular event over the short term (hazard ratio, 95% confidence interval: 2.00, 1.12-3.57, P = 0.02) and any fatal cardiovascular events (2.11, 1.21-3.68, P = 0.01) over the longer term. Among other echocardiographic parameters, LVM and LVM indexed to either BSA or height(2.7) predicted cardiovascular events over both short and longer term. In elderly treated hypertensive patients without heart failure, determining LVH by echocardiography is highly dependent on the methodology adopted. LVH-BSA(115/95) is a reliable predictor of future cardiovascular outcomes in the elderly. © American Journal of Hypertension, Ltd 2016. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  10. Application of Response Surface Methodology (RSM for Optimization of Operating Parameters and Performance Evaluation of Cooling Tower Cold Water Temperature

    Directory of Open Access Journals (Sweden)

    Ramkumar RAMAKRISHNAN

    2012-01-01

    Full Text Available The performance of a cooling tower was analyzed with various operating parameters tofind the minimum cold water temperature. In this study, optimization of operating parameters wasinvestigated. An experimental design was carried out based on central composite design (CCD withresponse surface methodology (RSM. This paper presents optimum operating parameters and theminimum cold water temperature using the RSM method. The RSM was used to evaluate the effectsof operating variables and their interaction towards the attainment of their optimum conditions.Based on the analysis, air flow, hot water temperature and packing height were high significanteffect on cold water temperature. The optimum operating parameters were predicted using the RSMmethod and confirmed through experiment.

  11. Comparison of sound absorbing performances of copper foam and iron foam with the same parameters

    Science.gov (United States)

    Yang, X. C.; Shen, X. M.; Xu, P. J.; Zhang, X. N.; Bai, P. F.; Peng, K.; Yin, Q.; Wang, D.

    2018-01-01

    Sound absorbing performances of the copper foam and the iron foam with the same parameters were investigated by the AWA6128A detector according to standing wave method. Two modes were investigated, which included the pure metal foam mode and the combination mode with the settled thickness of metal foam. In order to legibly compare the sound absorbing coefficients of the two metal foams, the detected sound frequency points were divided into the low frequency range (100 Hz ~ 1000 Hz), the middle frequency range (1000 Hz ~ 3200 Hz), and the high frequency range (3500 Hz ~ 6000 Hz). Sound absorbing performances of the two metal foams in the two modes were discussed within the three frequency ranges in detail. It would be calculated that the average sound absorbing coefficients of copper foam in the pure metal foam mode were 12.6%, 22.7%, 34.6%, 43.6%, 51.1%, and 56.2% when the thickness was 5 mm, 10 mm, 15 mm, 20 mm, 25 mm, and 30 mm. meanwhile, in the combination mode, the average sound absorbing coefficients of copper foam with the thickness of 10 mm were 30.6%, 34.8%, 36.3%, and 35.8% when the cavity was 5 mm, 10 mm, 15 mm, and 20 mm. In addition, those of iron foam in the pure metal foam mode were 13.4%, 20.1%, 34.4%, 43.1%, 49.6%, and 56.1%, and in the combination mode were 25.6%, 30.5%, 34.3%, and 33.4%.

  12. Assessment of impact of acoustic and nonacoustic parameters on performance and well-being

    Science.gov (United States)

    Mellert, Volker; Weber, Reinhard; Nocke, Christian

    2004-05-01

    It is of interest to estimate the influence of the environment in a specific work place area on the performance and well-being of people. Investigations have been carried out for the cabin environment of an airplane and for class rooms. Acoustics is only one issue of a variety of environmental factors, therefore the combined impact of temperature, humidity, air quality, lighting, vibration, etc. on human perception is the subject of psychophysical research. Methods for the objective assessment of subjective impressions have been developed for applications in acoustics for a long time, e.g., for concert hall acoustics, noise evaluation, and sound design. The methodology relies on questionnaires, measurement of acoustic parameters, ear-related signal processing and analysis, and on correlation of the physical input with subjective output. Methodology and results are presented from measurements of noise and vibration, temperature and humidity in aircraft simulators, and of reverberation, coloring, and lighting in a primary school, and of the environmental perception. [The work includes research with M. Klatte, A. Schick from the Psychology Department of Oldenburg University, and M. Meis from Hoerzentrum Oldenburg GmbH and with the European Project HEACE (for partners see www.heace.org).

  13. The Chaotic Prediction for Aero-Engine Performance Parameters Based on Nonlinear PLS Regression

    Directory of Open Access Journals (Sweden)

    Chunxiao Zhang

    2012-01-01

    Full Text Available The prediction of the aero-engine performance parameters is very important for aero-engine condition monitoring and fault diagnosis. In this paper, the chaotic phase space of engine exhaust temperature (EGT time series which come from actual air-borne ACARS data is reconstructed through selecting some suitable nearby points. The partial least square (PLS based on the cubic spline function or the kernel function transformation is adopted to obtain chaotic predictive function of EGT series. The experiment results indicate that the proposed PLS chaotic prediction algorithm based on biweight kernel function transformation has significant advantage in overcoming multicollinearity of the independent variables and solve the stability of regression model. Our predictive NMSE is 16.5 percent less than that of the traditional linear least squares (OLS method and 10.38 percent less than that of the linear PLS approach. At the same time, the forecast error is less than that of nonlinear PLS algorithm through bootstrap test screening.

  14. Fiber heart valve prosthesis: influence of the fabric construction parameters on the valve fatigue performances.

    Science.gov (United States)

    Vaesken, Antoine; Heim, Frederic; Chakfe, Nabil

    2014-12-01

    Transcatheter aortic valve replacement (TAVR) has become today a largely considered alternative technique to surgical valve replacement in patients who are not operable or patients with high risk for open chest surgery. However, the biological valve tissue used in the devices implanted clinically appears to be fragile material when folded for low diameter catheter insertion purpose and released in calcified environment with irregular geometry. Textile polyester material is characterized by outstanding folding and strength properties combined with proven biocompatibility. It could thereof be considered to replace biological valve leaflets in the TAVR procedure. The textile construction parameters must however be tuned to obtain a material compatible with the valve requested durability. In that context, one issue to be addressed is the friction effect that occurs between filaments and between yarns within a fabric under flexure loading. This phenomenon could be critical for the resistance of the material on the long term. The purpose of the present work is to assess the fatigue performances of textile valve prototypes made from different fabric constructions (monofilament, multifilament, calendered mutifilament) under accelerated cyclic loading. The goal is to identify, which construction is the best suited to long term fatigue stress. Results show that calendered multifilament and monofilament fabric constructions undergo strong ruptures already from 40 Mio cycles, while non calendered multifilament appears more durable. The rupture patterns observed point out that durability is directly related to the flexure stiffness level of the fibrous elements in the construction. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Positioning performance of the NTCM model driven by GPS Klobuchar model parameters

    Science.gov (United States)

    Hoque, Mohammed Mainul; Jakowski, Norbert; Berdermann, Jens

    2018-03-01

    Users of the Global Positioning System (GPS) utilize the Ionospheric Correction Algorithm (ICA) also known as Klobuchar model for correcting ionospheric signal delay or range error. Recently, we developed an ionosphere correction algorithm called NTCM-Klobpar model for single frequency GNSS applications. The model is driven by a parameter computed from GPS Klobuchar model and consecutively can be used instead of the GPS Klobuchar model for ionospheric corrections. In the presented work we compare the positioning solutions obtained using NTCM-Klobpar with those using the Klobuchar model. Our investigation using worldwide ground GPS data from a quiet and a perturbed ionospheric and geomagnetic activity period of 17 days each shows that the 24-hour prediction performance of the NTCM-Klobpar is better than the GPS Klobuchar model in global average. The root mean squared deviation of the 3D position errors are found to be about 0.24 and 0.45 m less for the NTCM-Klobpar compared to the GPS Klobuchar model during quiet and perturbed condition, respectively. The presented algorithm has the potential to continuously improve the accuracy of GPS single frequency mass market devices with only little software modification.

  16. Effects of Flux Precoating and Process Parameter on Welding Performance of Inconel 718 Alloy TIG Welds

    Science.gov (United States)

    Lin, Hsuan-Liang; Wu, Tong-Min; Cheng, Ching-Min

    2014-01-01

    The purpose of this study is to investigate the effect of activating flux on the depth-to-width ratio (DWR) and hot cracking susceptibility of Inconel 718 alloy tungsten inert gas (TIG) welds. The Taguchi method is employed to investigate the welding parameters that affect the DWR of weld bead and to achieve optimal conditions in the TIG welds that are coated with activating flux in TIG (A-TIG) process. There are eight single-component fluxes used in the initial experiment to evaluate the penetration capability of A-TIG welds. The experimental results show that the Inconel 718 alloy welds precoated with 50% SiO2 and 50% MoO3 flux were provided with better welding performance such as DWR and hot cracking susceptibility. The experimental procedure of TIG welding process using mixed-component flux and optimal conditions not only produces a significant increase in DWR of weld bead, but also decreases the hot cracking susceptibility of Inconel 718 alloy welds.

  17. Sensitivity functions for uncertainty analysis: Sensitivity and uncertainty analysis of reactor performance parameters

    International Nuclear Information System (INIS)

    Greenspan, E.

    1982-01-01

    This chapter presents the mathematical basis for sensitivity functions, discusses their physical meaning and information they contain, and clarifies a number of issues concerning their application, including the definition of group sensitivities, the selection of sensitivity functions to be included in the analysis, and limitations of sensitivity theory. Examines the theoretical foundation; criticality reset sensitivities; group sensitivities and uncertainties; selection of sensitivities included in the analysis; and other uses and limitations of sensitivity functions. Gives the theoretical formulation of sensitivity functions pertaining to ''as-built'' designs for performance parameters of the form of ratios of linear flux functionals (such as reaction-rate ratios), linear adjoint functionals, bilinear functions (such as reactivity worth ratios), and for reactor reactivity. Offers a consistent procedure for reducing energy-dependent or fine-group sensitivities and uncertainties to broad group sensitivities and uncertainties. Provides illustrations of sensitivity functions as well as references to available compilations of such functions and of total sensitivities. Indicates limitations of sensitivity theory originating from the fact that this theory is based on a first-order perturbation theory

  18. Influence of the layer parameters on the performance of the CdTe solar cells

    Science.gov (United States)

    Haddout, Assiya; Raidou, Abderrahim; Fahoume, Mounir

    2018-03-01

    Influence of the layer parameters on the performances of the CdTe solar cells is analyzed by SCAPS-1D. The ZnO: Al film shows a high efficiency than SnO2:F. Moreover, the thinner window layer and lower defect density of CdS films are the factor in the enhancement of the short-circuit current density. As well, to increase the open-circuit voltage, the responsible factors are low defect density of the absorbing layer CdTe and high metal work function. For the low cost of cell production, ultrathin film CdTe cells are used with a back surface field (BSF) between CdTe and back contact, such as PbTe. Further, the simulation results show that the conversion efficiency of 19.28% can be obtained for the cell with 1-μm-thick CdTe, 0.1-μm-thick PbTe and 30-nm-thick CdS.

  19. Impact of droplet evaporation rate on resulting in vitro performance parameters of pressurized metered dose inhalers.

    Science.gov (United States)

    Sheth, Poonam; Grimes, Matthew R; Stein, Stephen W; Myrdal, Paul B

    2017-08-07

    Pressurized metered dose inhalers (pMDIs) are widely used for the treatment of pulmonary diseases. The overall efficiency of pMDI drug delivery may be defined by in vitro parameters such as the amount of drug that deposits on the model throat and the proportion of the emitted dose that has particles that are sufficiently small to deposit in the lung (i.e., fine particle fraction, FPF). The study presented examines product performance of ten solution pMDI formulations containing a variety of cosolvents with diverse chemical characteristics by cascade impaction with three inlets (USP induction port, Alberta Idealized Throat, and a large volume chamber). Through the data generated in support of this study, it was demonstrated that throat deposition, cascade impactor deposition, FPF, and mass median aerodynamic diameter of solution pMDIs depend on the concentration and vapor pressure of the cosolvent, and the selection of model throat. Theoretical droplet lifetimes were calculated for each formulation using a discrete two-stage evaporation process model and it was determined that the droplet lifetime is highly correlated to throat deposition and FPF indicating that evaporation kinetics significantly influences pMDI drug delivery. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Effects of stocking density on growth performance, feather growth, intestinal development, and serum parameters of geese.

    Science.gov (United States)

    Yin, L Y; Wang, Z Y; Yang, H M; Xu, L; Zhang, J; Xing, H

    2017-09-01

    This experiment was conducted to evaluate the effects of stocking density on the growth performance, feather growth, intestinal development, and serum parameters of geese. In total, 336 healthy, 28-day-old, male Yangzhou goslings were randomly allotted to 30 plastic wire-floor pens according to 5 stocking densities (2, 3, 4, 5 and 6 birds/m2). The results showed that with the stocking density increased from 2 birds/m2 to 6 birds/m2, the body weights of geese at 42 d (P density was increased to 6 birds/m2. Serum concentrations of alkaline phosphatase (P = 0.013) and triiodothyronine (P density increased. The serum thyroxine concentration of geese from the 6 birds/m2 group was lower than that of geese from the other groups (P density will adversely influence thyroid function and the developments of the body weight, body size, feathers, and small intestine. Under our experimental conditions, we recommend that the stocking density of geese should be kept to 5 or fewer birds/m2 to avoid the negative effects of high stocking density on geese. © 2017 Poultry Science Association Inc.

  1. Optimizing Performance Parameters of Chemically-Derived Graphene/p-Si Heterojunction Solar Cell.

    Science.gov (United States)

    Batra, Kamal; Nayak, Sasmita; Behura, Sanjay K; Jani, Omkar

    2015-07-01

    Chemically-derived graphene have been synthesized by modified Hummers method and reduced using sodium borohydride. To explore the potential for photovoltaic applications, graphene/p-silicon (Si) heterojunction devices were fabricated using a simple and cost effective technique called spin coating. The SEM analysis shows the formation of graphene oxide (GO) flakes which become smooth after reduction. The absence of oxygen containing functional groups, as observed in FT-IR spectra, reveals the reduction of GO, i.e., reduced graphene oxide (rGO). It was further confirmed by Raman analysis, which shows slight reduction in G-band intensity with respect to D-band. Hall effect measurement confirmed n-type nature of rGO. Therefore, an effort has been made to simu- late rGO/p-Si heterojunction device by using the one-dimensional solar cell capacitance software, considering the experimentally derived parameters. The detail analysis of the effects of Si thickness, graphene thickness and temperature on the performance of the device has been presented.

  2. Somatic parameters of 17 year old soccer players in the older youth category in relation to sports performance

    Directory of Open Access Journals (Sweden)

    Petr Kutáč

    2013-09-01

    Full Text Available BACKGROUND: Somatic parameters are included not only in the general structure of sporting performance, but also in the structure of sporting performance in soccer. In light of this structure, higher performance players should have better somatic performance prerequisites, and their somatic parameters should differ from players with lower performance levels. OBJECTIVE: The aim of the study is to assess the somatic parameters of players with different performance levels. METHODS: The research included 90 soccer players in the age of 17 years in three performance categories playing in the junior competition in the Czech Republic. Average age of the individual levels – highest performance 17.61 ± 0.48, middle performance 17.50 ± 0.50, lowest performance 17.50 ± 0.50 years. The following was monitored – basic anthropometric parameters (body weight, body height, somatotype (Heath-Carter, representation of body fat (BF, fat free mass (FFM and the total body water (TBW. The Tanita 418 MA tetrapolar bioelectrical impedance (BIA scale was used for the determination of the representation of BF and the TBW. All players were measured at the beginning of the competition period in the same year. All measurements were implemented in the morning hours by the same person with corresponding experience. RESULTS: The average values of somatic parameters measured in the individual performance categories show that we can only consider them to be an indicator of sporting performance up to a particular performance level. The boundary was the middle performance level (teams playing regional competition as their mean values of the monitored somatic parameters significantly differed from the mean values of players at the lowest performance level (teams playing at the district and municipal levels but they did not differ when compared with the mean values of the players at the highest performance level (teams playing the top junior league. CONCLUSIONS

  3. Outbreak of Pseudomonas aeruginosa bacteraemia in a haematology department

    DEFF Research Database (Denmark)

    Rasmussen, Benjamin Schnack; Christensen, Nikolas; Sørensen, Jan

    2015-01-01

    the outbreak and 12 months later. The audits were conducted by the method of direct observation. RESULTS: Several PFGE types were involved with no clear association to isolates from environmental samples. The audit revealed poor hygiene related to the handling of central venous catheters. After optimising......INTRODUCTION: Infection by Pseudomonas aeruginosa represents a major cause of morbidity and mortality among immunocompromised patients. In Denmark, an increase in P. aeruginosa isolates from blood cultures from a haematology department prompted a hygienic audit in 2007. METHODS: Blood cultures...... catheter hygiene, the number of P. aeruginosa bacteraemia cases fell significantly. CONCLUSION: Since no clear association between patient and environmental genotype was established, it was suspected that central venous catheters were the main portal of entry. This was further supported by a simultaneous...

  4. Haematological status in elite long-distance runners

    DEFF Research Database (Denmark)

    Suetta, C; Kanstrup, I L; Fogh-Andersen, N

    1996-01-01

    In 10 female and eight male Danish elite middle- and long-distance runners, haematological status, including blood volume, was examined. Haemoglobin, haematocrit and serum (s)-ferritin concentrations were all within the normal range. In both men and women, blood volume, plasma volume...... and erythrocyte volume were increased in relation to various reference values. However, the runners had a low body weight due to a reduced fat level, 9.5% (7.3-15.1%) fat for the women, 5.9% (5.0-8.8%) fat (median and ranges) for the men, measured by dual-energy X-ray absorptiometry (DEXA) scanning. When...... the runners' body weights were 'normalized' to a reference population (25% fat for women, 15% fat for men), only plasma volume remained increased in relation to body weight for the women, whereas all the volumes remained increased for the men. This confirms that endurance training induces a true increased...

  5. Aplastic anemia: clinico haematological features, treatment and outcome analysis

    International Nuclear Information System (INIS)

    Wali, R.; Fadoo, Z.; Naqvi, M.A.

    2011-01-01

    To determine the clinico haematological features, treatment and outcome of children diagnosed with aplastic anemia at a single institution. Study Design: Observational study. Place and Duration of Study: The Aga Khan University Hospital, Karachi, from January 1999 till December 2008. Methodology: Medical records of children aged less than 15 years of age diagnosed with aplastic anemia were reviewed. Clinico haematological features, treatment and its response to therapy and outcome were recorded. Results were described in percentages. Results: Ninety patients were diagnosed to have aplastic anemia (AA); 65 were male during the study period. Age ranged from 1 to 15 years. Fever in 65 patients (72.2%), pallor in 53 (58.8%), skin bleeding in 49 (54.4%) and epistaxis in 31(34.4%) were the most common and frequent presenting features. Congenital (Fanconi's) anemia was found in 15 (16.6%) and acquired idiopathic in 75 (83.4%) of patients. Very severe aplastic anemia (VSAA) was seen in 29 (32.2%), 26 (28.9%) had severe AA and 17 (18.9%) had moderate AA. Eight patients (8.9%) underwent haematopoietic stem cell transplantation (HSCT), 12 (13.3%) received immunosuppressive therapy (IST) and 70 patients (77.7%) received other and supportive therapy. Five (62.5%) patients showed complete response to HSCT and 3 (37.5%) failed to engraft. IST showed complete response in 3 (25%), partial response in 5 (41.6%) and no response in 4 (33.3%). Twenty two patients (24.4%) expired either due to infection in 16 (72.7%, fungal in 6, bacterial in 10) and intracranial haemorrhage in 6 (27.3%) cases. Conclusion: Majority of cases with AA were acquired and idiopathic in etiology. VSAA and SAA were frequent. Response to HSCT and IST was sub-optimal. (author)

  6. Ranking Of The Performance Of Some Climatological Parameters In The Easement Of Solar Radiation In The Mina Environment Central Nigeria

    International Nuclear Information System (INIS)

    Abubakar, S.Y.

    2004-01-01

    Four models each based on a single climatological factors were proposed to evaluate the strength of the performance of each parameter in estimating solar radiation in Minna. The climatological parameters are percentage of sunshine hours, temperature ratio, humidity and cloud cover. Based on the MAB and RMSE method the sunshine hours duration was found to be the most efficient parameter for predicting the monthly and annual performance of models compared with the model based on the temperature ratio closely follow the model based on sunshine data while model based on the cloud cover was found to have the worst performance. Generally the model based on the sunshine hours performed better than the rest during the rainy season while the model based on the temperature ratio outperformed the rest of the models during the harmattan season. However both models based on the sunshine hours and temperature ratio were equally found to have good performance during the dry season

  7. Diagnostic performance of whole-body MRI for the detection of persistent or relapsing disease in multiple myeloma after stem cell transplantation

    Energy Technology Data Exchange (ETDEWEB)

    Bannas, Peter; Hentschel, Hannah B.; Bley, Thorsten A.; Derlin, Thorsten; Yamamura, Jin; Adam, Gerhard; Weber, Christoph [University Medical Center Hamburg-Eppendorf, Department of Diagnostic and Interventional Radiology, Hamburg (Germany); Treszl, Andras; Eulenburg, Christine [University Medical Center Hamburg-Eppendorf, Department of Medical Biometry and Epidemiology, Hamburg (Germany); Stuebig, Thomas; Kroeger, Nicolaus [University Medical Center Hamburg-Eppendorf, Department of Stem Cell Transplantation, Hamburg (Germany)

    2012-09-15

    To compare the diagnostic performance of whole-body MRI (WBMRI) with haematological parameters for detecting persistent or relapsing disease in patients with multiple myeloma after stem cell transplantation. Sixty-six WBMRI acquisitions were performed in 33 patients with multiple myeloma at two time points after stem cell transplantation. Extent of disease and inter-test dynamics of intra- and extramedullary myeloma manifestations were compared (kappa statistics) with Uniform Response Criteria, comprising haematological parameters. Using data from 66 sequential WBMRI acquisitions in 33 patients, 10 patients (30.3 %) were classified as having progressive disease and 23 (69.7 %) as being in remission. Eight (80 %) of the ten patients with progressive disease revealed intramedullary lesions, and two patients (20 %) had intra- and extramedullary lesions. WBMRI and laboratory tests were concordant in 26/33 (78.8 %) patients. We found an agreement of 51.2 %, 95 % confidence interval 19.8 %-82.6 %, between results from WBMRI and haematological parameters. WBMRI had a sensitivity of 63.6 %, specificity of 86.4 %, PPV of 70.0 %, NPV of 82.6 % and accuracy of 78.8 % for detection of remission. WBMRI allows the detection and exact localisation of intra- and extramedullary myeloma manifestations after stem cell transplantation, but shows only moderate agreement with routinely performed laboratory tests for determination of remission. (orig.)

  8. Perceived need for information among patients with a haematological malignancy: associations with information satisfaction and treatment decision-making preferences.

    Science.gov (United States)

    Rood, Janneke A J; van Zuuren, Florence J; Stam, Frank; van der Ploeg, Tjeerd; Eeltink, Corien; Verdonck-de Leeuw, Irma M; Huijgens, Peter C

    2015-06-01

    For patients with haematological malignancies, information on disease, prognosis, treatment and impact on quality of life is of the utmost importance. To gain insight into the perceived need for information in relation to sociodemographic and clinical parameters, comorbidity, quality of life (QoL) and information satisfaction, we compiled a questionnaire based on existing validated questionnaires. A total of 458 patients diagnosed with a haematological malignancy participated. The perceived need for information was moderate to high (40-70%). Multivariate regression analyses showed that a higher need for information was related to younger age, worse QoL, being member of a patient society and moderate comorbidity. The need for disease and treatment-related information was higher than the need for psychosocial information. A higher need for disease and treatment-related information was associated to being diagnosed with multiple myeloma. A higher need for psychosocial information was related to a lower educational level. The information provision could be improved according to 41% of the patients. Higher satisfaction with provided information was associated with better QoL. Most patients (62%) reported that they wanted to be fully informed about their illness and actively involved in treatment decision-making. The results contribute to improving patient-tailored information provision and shared decision-making in clinical practice. Copyright © 2014 John Wiley & Sons, Ltd.

  9. Analysis Of Impact Of Various Parameters On BER Performance For IEEE 802.11b

    Directory of Open Access Journals (Sweden)

    Nilesh B. Kalani

    2015-08-01

    Full Text Available Abstract This paper discusses about IEEE 802.11b simulation model implemented using LabVIEW software and its analyses for impact on bit error rate BER for different parameters as channel type channel number data transmission rate and packet size. Audio file is being transmitted processed and analyzed using the model for various parameters. This paper gives analysis of BER verses ESN0 for various parameter like data rate packet size and communication channel for the IEEE 802.11b simulation model generated using LabVIEW. It is proved that BER can be optimized by tweaking different parameters of wireless communication system.

  10. Investigation on the effect of the reservoir variables and operational parameters on SAGD performance

    Energy Technology Data Exchange (ETDEWEB)

    Hashemi Kiasari, H.; Naderifar, A. [AmirKabir University of Technology, Tehran (Iran, Islamic Republic of). Petroleum Engineering Dept.; Sedaee Sola, B. [University of Tehran (Iran, Islamic Republic of). Faculty of Engineering. Inst. of Petroleum Engineering], e-mail: sedaeesola@yahoo.com

    2010-04-15

    Steam injection is the most important thermal enhanced oil recovery method. One typical procedure is Steam- Assisted Gravity Drainage (SAGD), which is a promising recovery process to produce heavy oil and bitumen. The method ensures a stable displacement of steam at economical rates by using gravity as the driving force and a pair of horizontal wells for injection/production. There are numerous studies done on SAGD in conventional reservoirs, but the majority of them focus on the investigation of the process in microscopic scale. In this study, we investigate the SAGD process with a preheating period, using steam circulation in well pair on a field scale. The synthetic homogenous model was constructed by CMG and simulated using the STARS module. The effects of operational parameters, such as preheating period, vertical well spacing, well pair length, steam quality and production pressure, and reservoir variables, such as rock porosity and permeability, vertical-to-horizontal permeability ratio, thermal conductivity of the formation and rock heat capacity, on the SAGD performance were investigated. The results show that the preheating period affects mainly the initial stages of production. Due to preheating, the well pair communication with the higher vertical distances is also established; therefore, there was no considerable difference between oil productions in various well spacing cases. As steam quality increases, the oil production in later production times also increases. At shorter well pair, more steam can be injected per unit length of well, but, on the other hand, the production well recovers less heated oil area; therefore the well pair length should be optimized in all cases. By decreasing the production well bottom-hole pressure, more heated oil in near well region is produced; therefore, the injected steam raises more in the depleted area. The results of the simulations show that very low permeability leads to a fully unsuccessful SAGD process. In the

  11. A Study on Course of Infection and Haematological Changes in falciparum-Infected in Comparison with Artemisinin(s-Treated Mice

    Directory of Open Access Journals (Sweden)

    Kalyan Kumar Kuthala

    2013-01-01

    Full Text Available To find out the efficacy and effect of artemisinin derivatives on haematological indices, C57BL/6J mice were challenged with Plasmodium falciparum and treated with therapeutic doses of AS, AE, and AL. Course of infection was studied in the infected and treated groups up to day 42. Peak level of parasitaemia (38% was observed on day 11 in infected group. Haematological indices indicated significant (P0.05 in all drug-treated groups. Percent of peak parasitaemia was much reduced in AL- (3.2% on day 3 treated group in comparison with AE- (2.4% on day 4 and AS- (4% on day 2 treated groups. Parasites were completely cleared on day 6 in AS group, day 5 in AE group, and day 4 in AL group. Hence, our results strongly support that combination therapy has high efficacy rates than monotherapy. No adverse effects were observed on haematological parameters when animals were treated with therapeutic dosages.

  12. Effects of Graded Levels of Montmorillonite on Performance, Hematological Parameters and Bone Mineralization in Weaned Pigs

    Directory of Open Access Journals (Sweden)

    Q. W. Duan

    2013-11-01

    Full Text Available The aim of this study was to investigate the effects of graded levels of montmorillonite, a constituent of clay, on performance, hematological parameters and bone mineralization in weaned pigs. One hundred and twenty, 35-d-old crossbred pigs (Duroc×Large White×Landrace, 10.50±1.20 kg were used in a 28-d experiment and fed either an unsupplemented corn-soybean meal basal diet or similar diets supplemented with 0.5, 1.0, 2.5 or 5.0% montmorillonite added at the expense of wheat bran. Each treatment was replicated six times with four pigs (two barrows and two gilts per replicate. Feed intake declined (linear and quadratic effect, p< 0.01 with increasing level of montmorillonite while feed conversion was improved (linear and quadratic effect, p<0.01. Daily gain was unaffected by dietary treatment. Plasma myeloperoxidase declined linearly (p = 0.03 with increasing dietary level of montmorillonite. Plasma malondialdehyde and nitric oxide levels were quadratically affected (p<0.01 by montmorillonite with increases observed for pigs fed the 0.5 and 1.0% levels which then declined for pigs fed the 2.5 and 5.0% treatments. In bone, the content of potassium, sodium, copper, iron, manganese and magnesium were decreased (linear and quadratic effect, p<0.01 in response to an increase of dietary montmorillonite. These results suggest that dietary inclusion of montmorillonite at levels as high as 5.0% does not result in overt toxicity but could induce potential oxidative damage and reduce bone mineralization in pigs.

  13. Genetic parameters and genetic and phenotypic trends of performance traits of equines from the Brazilian Army

    Directory of Open Access Journals (Sweden)

    Mariana de Almeida Dornelles

    2012-06-01

    Full Text Available The objective of this research was to compare the magnitude of genetic parameters (coefficients of heritability and genetic correlation as estimated by the Restricted Maximum Likelihood (REML method and Bayesian Inference, and to estimate the genetic and phenotypic trends to the traits height at the withers (HW24 and weight at 24 months of age (W24. The average heritability estimated by Bayesian Inference to HW24 was 0.47, and it was lower than that obtained by REML bi-trait analysis (0.52; however, the value estimated to W24 (0.39 was higher than that obtained by REML bi-trait analysis (0.38. The genetic correlation estimate between W24 and HW24 traits obtained by the REML method (0.66 was lower than that obtained by the Bayesian Inference Method (0.72. From the regression of the average additive genetic merit in the year of birth of the animals, it was found that the averaged genetic values of the animals for HW24 showed a genetic trend near zero (-0.0008cm/year, and the averaged genetic values for W24 showed a negative trend of -0.38 kg/year. The values to the direct heritability estimated for HW24 and W24 suggest that the direct selection for these traits can provide genetic gain in this population. The genetic correlation between the traits, high and positive, suggests that the selection for HW24 should promote increase in W24 at this age. The genetic trends obtained for the traits studied, near zero, indicate that the selection performed produced a slight reduction of the weight of the animals at 24 months of age; however, it did not promote increase in height at the wither at this same age, in this population.

  14. Sensitivity of Key Parameters in Aerodynamic Wind Turbine Rotor Design on Power and Energy Performance

    International Nuclear Information System (INIS)

    Bak, Christian

    2007-01-01

    In this paper the influence of different key parameters in aerodynamic wind turbine rotor design on the power efficiency, C p , and energy production has been investigated. The work was divided into an analysis of 2D airfoils/blade sections and of entire rotors. In the analysis of the 2D airfoils it was seen that there was a maximum of the local C p for airfoils with finite maximum C l /C d values. The local speed ratio should be between 2.4 and 3.8 for airfoils with maximum c l /c d between 50 and 200, respectively, to obtain maximum local C p . Also, the investigation showed that Re had a significant impact on CP and especially for Re p for rotors was made with three blades and showed that with the assumption of constant maximum c l /c d along the entire blade, the design tip speed ratio changed from X=6 to X=12 for c l /cd=50 and c l /c d =200, respectively, with corresponding values of maximum c p of 0.46 and 0.525. An analysis of existing rotors re-designed with new airfoils but maintaining the absolute thickness distribution to maintain the stiffness showed that big rotors are more aerodynamic efficient than small rotors caused by higher Re. It also showed that the design tip speed ratio was very dependent on the rotor size and on the assumptions of the airfoil flow being fully turbulent (contaminated airfoil) or free transitional (clean airfoil). The investigations showed that rotors with diameter D=1.75m, should be designed for X around 5.5, whereas rotors with diameter D=126m, should be designed for Xbetween 6.5 and 8.5, depending on the airfoil performance

  15. Parameter definition using vibration prediction software leads to significant drilling performance improvements

    Energy Technology Data Exchange (ETDEWEB)

    Amorim, Dalmo; Hanley, Chris Hanley; Fonseca, Isaac; Santos, Juliana [National Oilwell Varco, Houston TX (United States); Leite, Daltro J.; Borella, Augusto; Gozzi, Danilo [Petroleo Brasileiro S.A. (PETROBRAS), Rio de Janeiro, RJ (Brazil)

    2012-07-01

    The understanding and mitigation of downhole vibration has been a heavily researched subject in the oil industry as it results in more expensive drilling operations, as vibrations significantly diminish the amount of effective drilling energy available to the bit and generate forces that can push the bit or the Bottom Hole Assembly (BHA) off its concentric axis of rotation, producing high magnitude impacts with the borehole wall. In order to drill ahead, a sufficient amount of energy must be supplied by the rig to overcome the resistance of the drilling system, including the reactive torque of the system, drag forces, fluid pressure losses and energy dissipated by downhole vibrations, then providing the bit with the energy required to fail the rock. If the drill string enters resonant modes of vibration, not only does it decreases the amount of available energy to drill, but increases the potential for catastrophic downhole equipment and drilling bit failures. In this sense, the mitigation of downhole vibrations will result in faster, smoother, and cheaper drilling operations. A software tool using Finite Element Analysis (FEA) has been developed to provide better understanding of downhole vibration phenomena in drilling environments. The software tool calculates the response of the drilling system at various input conditions, based on the design of the wellbore along with the geometry of the Bottom Hole Assembly (BHA) and the drill string. It identifies where undesired levels of resonant vibration will be driven by certain combinations of specific drilling parameters, and also which combinations of drilling parameters will result in lower levels of vibration, so the least shocks, the highest penetration rate and the lowest cost per foot can be achieved. With the growing performance of personal computers, complex software systems modeling the drilling vibrations using FEA has been accessible to a wider audience of field users, further complimenting with real time

  16. Bone marrow stroma in idiopathic myelofibrosis and other haematological diseases. An immunohistochemical study

    DEFF Research Database (Denmark)

    Lisse, I; Hasselbalch, H; Junker, P

    1991-01-01

    Bone marrow stroma was investigated immunohistochemically in 31 patients with haematological diseases, mainly idiopathic myelofibrosis (n = 8) and related chronic myeloproliferative disorders (n = 14). The bone marrow from patients with idiopathic myelofibrosis and some CML patients showed marked...

  17. Guidebook for performance assessment parameters used in the Waste Isolation Pilot Plant compliance certification application. Volume 1: Main report

    International Nuclear Information System (INIS)

    Howarth, S.M.; Martell, M.A.; Weiner, R.; Lattier, C.

    1998-06-01

    The Waste Isolation Pilot Plant (WIPP) Compliance Certification Application (CCA) Performance Assessment (PA) Parameter Database and its ties to supporting information evolved over the course of two years. When the CCA was submitted to the Environmental Protection Agency (EPA) in October 1996, information such as identification of parameter value or distribution source was documented using processes established by Sandia National Laboratories WIPP Quality Assurance Procedures. Reviewers later requested additional supporting documentation, links to supporting information, and/or clarification for many parameters. This guidebook is designed to document a pathway through the complex parameter process and help delineate flow paths to supporting information for all WIPP CCA parameters. In addition, this report is an aid for understanding how model parameters used in the WIPP CCA were developed and qualified. To trace the source information for a particular parameter, a dual-route system was established. The first route uses information from the Parameter Records Package as it existed when the CCA calculations were run. The second route leads from the EPA Parameter Database to additional supporting information

  18. Guidebook for performance assessment parameters used in the Waste Isolation Pilot Plant compliance certification application. Volume 2: Appendices

    International Nuclear Information System (INIS)

    Howarth, S.M.; Martell, M.A.; Weiner, R.; Lattier, C.

    1998-06-01

    The Waste Isolation Pilot Plant (WIPP) Compliance Certification Application (CCA) Performance Assessment (PA) Parameter Database and its ties to supporting information evolved over the course of two years. When the CCA was submitted to the Environmental Protection Agency (EPA) in October 1996, information such as identification of parameter value or distribution source was documented using processes established by Sandia National Laboratories WIPP Quality Assurance Procedures. Reviewers later requested additional supporting documentation, links to supporting information, and/or clarification for many parameters. This guidebook is designed to document a pathway through the complex parameter process and help delineate flow paths to supporting information for all WIPP CCA parameters. In addition, this report is an aid for understanding how model parameters used in the WIPP CCA were developed and qualified. To trace the source information for a particular parameter, a dual-route system was established. The first route uses information from the Parameter Records package as it existed when the CCA calculations were run. The second route leads from the EPA Parameter Database to additional supporting information

  19. Magnetic resonance imaging (MRI) of liver and brain in haematologic-organic patients with fever of unknown origin

    International Nuclear Information System (INIS)

    Heussel, C.P.; Kauczor, H.U.; Poguntke, M.; Schadmand-Fischer, S.; Mildenberger, P.; Thelen, M.; Heussel, G.

    1998-01-01

    To examine the advantage of liver and brain MRI in clinically anomalous haematological patients with fever of unknown origin. Material and Methods: Twenty liver MRI (T 2 -TSE, T 2 -HASTE, T 1 -FLASH±Gd dynamic) and 16 brain MRI (T 2 -TSE, FLAIR, T 1 -TSE±Gd) were performed searching for a focus of fever with a suspected organ system. Comparison with clinical follow-up. Results: suspected organ system. Comparison with clinical follow-up. Results: A focus was detected in 11/20 liver MRI. Candidiasis (n=3), mycobacteriosis (n=2), relapse of haematological disease (n=3), graft versus host disease (n=1), non-clarified (n=2). The remaining 9 cases with normal MRI were not suspicious of infectious hepatic disease during follo-wup. In brain MRI, 3/16 showed a focus (toxoplasmosis, aspergillosis, mastoiditis). Clinical indication for an infectious involvement of the brain was found in 4/16 cases 2--5 months after initially normal brain MRI. No suspicion of an infectious involvement of brain was present in the remaining 9/16 cases. Conclusion: In case of fever of unknown origin and suspicion of liver involvement, MRI of the liver should be performed due to data given in literature and its sensitivity of 100%. Because of the delayed detectability of cerebral manifestations, in cases of persisting suspicion even a previously normal MRI of the brain should be repeated. (orig.) [de

  20. The performance of simulated annealing in parameter estimation for vapor-liquid equilibrium modeling

    Directory of Open Access Journals (Sweden)

    A. Bonilla-Petriciolet

    2007-03-01

    Full Text Available In this paper we report the application and evaluation of the simulated annealing (SA optimization method in parameter estimation for vapor-liquid equilibrium (VLE modeling. We tested this optimization method using the classical least squares and error-in-variable approaches. The reliability and efficiency of the data-fitting procedure are also considered using different values for algorithm parameters of the SA method. Our results indicate that this method, when properly implemented, is a robust procedure for nonlinear parameter estimation in thermodynamic models. However, in difficult problems it still can converge to local optimums of the objective function.

  1. Elevation profile influence at key contractual performance parameters for LDS (Leak Detection Systems) based on compensated volume balance

    Energy Technology Data Exchange (ETDEWEB)

    Liebenberg, Lieb [TRANSNET Pipeline, Durban (South Africa); Bueno, David; Passos, Rafaela [KANOPUS Consulting, Rio de Janeiro, RJ (Brazil)

    2009-07-01

    This paper describes and discusses procedures and correlations to estimate performance parameters for Leak Detection Systems based on Compensation Volume Balance, at the portions not usually covered by international standards (like, API RP 1130). These parameters include: minimum acceptable leakage to be detected, under steady state conditions, based on flow measurement uncertainty, observed for both pipeline head and tail; an actual flow rate uncertainty against the one informed by the flow meter manufacturer documentation; the reference flow rate for steady state conditions; and the sensitivity one may expect for the system against a given probability of false alarms (i.e., the ways to correlate reliability, the main performance parameter as per API RP 1130 and sensitivity, the second one). A question usually not considered is: how the elevation profile may affect some of these parameters. That is the second main objective addressed herein, with actual examples employed in a South African multi product pipeline. (author)

  2. Estimating Parameters for the PVsyst Version 6 Photovoltaic Module Performance Model

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Clifford [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-10-01

    We present an algorithm to determine parameters for the photovoltaic module perf ormance model encoded in the software package PVsyst(TM) version 6. Our method operates on current - voltage (I - V) measured over a range of irradiance and temperature conditions. We describe the method and illustrate its steps using data for a 36 cell crystalli ne silicon module. We qualitatively compare our method with one other technique for estimating parameters for the PVsyst(TM) version 6 model .

  3. Tuning of the PI Controller Parameters of a PMSG Wind Turbine to Improve Control Performance under Various Wind Speeds

    OpenAIRE

    Yun-Su Kim; Il-Yop Chung; Seung-Il Moon

    2015-01-01

    This paper presents a method to seek the PI controller parameters of a PMSG wind turbine to improve control performance. Since operating conditions vary with the wind speed, therefore the PI controller parameters should be determined as a function of the wind speed. Small-signal modeling of a PMSG WT is implemented to analyze the stability under various operating conditions and with eigenvalues obtained from the small-signal model of the PMSG WT, which are coordinated by adjusting the PI con...

  4. Investigation of Dip-Coating Parameters Effect on The Performance of Alumina-Polydimethylsiloxane Nanofiltration Membranes for Desalination

    OpenAIRE

    Mohammad Hadi Yousefi; Mohamad Mehdi Zerafat; Majid Shokri Doodeji; Samad Sabbaghi

    2017-01-01

    The objective of this work is to investigate the effect of dip-coating parameters on the performance of Alumina-PDMS hybrid nanofiltration membranes for water desalination. Ceramic supports used in this work were prepared with a 340 nm average pore size and 34% total porosity. The aim is to determine optimum conditions of dipping time, PDMS concentration, and withdrawal speed in order to achieve high rejection and flux values. Dip-coating parameters were considered as dipping time (60 - 120 s...

  5. Analyzing the shape parameter effects on the performance of the mixed-flow fan using CFD and Factorial design

    International Nuclear Information System (INIS)

    Jung, Uk Hee; Kim, Joon Hyung; Kim, Sung; Kim, Jin Hyuk; Choi, Young Seok

    2016-01-01

    Fans are representative turbo-machinery widely used for ventilation throughout the industrial world. Recently, as the importance of energy saving has been magnified with the fans, the demand for the fans with high efficiency and performance has been increasing. The representative method for enhancing the performance includes design optimization; in practice, fan performance can be improved by changing the shape parameters such as those of meridional plane, impeller, and diffuser. Before optimizing the efficient design, a process of screening to select important design parameters is essential. The present study aimed to analyze the effects of mixed-flow fans' shape parameters on fan performance (static pressure and fan static efficiency) and derive optimum models based on the results. In this study, the shape parameters considered in the impeller domain are as follows: tip clearance, number of blades, beta angle of Leading edge (LE) in the blade, and beta angle of Trailing edge (TE) in the blade. The shape parameters considered in the diffuser domain are as follows: meridional length of the Guide vane (GV), number of GV, beta angle of LE in the GV and beta angle of TE in the GV. The effects of individual shape parameters were analyzed using the CFD (Computational fluid dynamic) and DOE (Design of experiments) methods. The reliability of CFD was verified through the comparison between preliminary fan model's experiment results and CFD results, and screening processes were implemented through 24-1 fractional factorial design. From the analysis of DOE results, it could be seen that the tip clearance and the number of blades in the impeller domain greatly affected the fan performance, and the beta angle of TE at the GV in the diffuser domain greatly affected the fan performance. Finally, the optimum models with improved fan performance were created using linear regression equations derived from 24-1 fractional factorial design.

  6. Strengthening medical education in haematology and blood transfusion: postgraduate programmes in Tanzania.

    Science.gov (United States)

    Makani, Julie; Lyimo, Magdalena; Magesa, Pius; Roberts, David J

    2017-06-01

    Haematology and blood transfusion, as a clinical and laboratory discipline, has a far-reaching impact on healthcare both through direct patient care as well as provision of laboratory and transfusion services. Improvement of haematology and blood transfusion may therefore be significant in achieving advances in health in Africa. In 2005, Tanzania had one of the lowest distributions of doctors in the world, estimated at 2·3 doctors per 100 000 of population, with only one haematologist, a medical doctor with postgraduate medical education in haematology and blood transfusion. Here, we describe the establishment and impact of a postgraduate programme centred on Master of Medicine and Master of Science programmes to build the capacity of postgraduate training in haematology and blood transfusion. The programme was delivered through Muhimbili University of Health and Allied Sciences (MUHAS) with partnership from visiting medical and laboratory staff from the UK and complemented by short-term visits of trainees from Tanzania to Haematology Departments in the UK. The programme had a significant impact on the development of human resources in haematology and blood transfusion, successfully training 17 specialists with a significant influence on delivery of health services and research. This experience shows how a self-sustaining, specialist medical education programme can be developed at low cost within Lower and Middle Income Countries (LMICs) to rapidly enhance delivery of capacity to provide specialist services. © 2017 John Wiley & Sons Ltd.

  7. Diagnostic performances of shear wave elastography: which parameter to use in differential diagnosis of solid breast masses?

    Science.gov (United States)

    Lee, Eun Jung; Jung, Hae Kyoung; Ko, Kyung Hee; Lee, Jong Tae; Yoon, Jung Hyun

    2013-07-01

    To evaluate which shear wave elastography (SWE) parameter proves most accurate in the differential diagnosis of solid breast masses. One hundred and fifty-six breast lesions in 139 consecutive women (mean age: 43.54 ± 9.94 years, range 21-88 years), who had been scheduled for ultrasound-guided breast biopsy, were included. Conventional ultrasound and SWE were performed in all women before biopsy procedures. Ultrasound BI-RADS final assessment and SWE parameters were recorded. Diagnostic performance of each SWE parameter was calculated and compared with those obtained when applying cut-off values of previously published data. Performance of conventional ultrasound and ultrasound combined with each parameter was also compared. Of the 156 breast masses, 120 (76.9 %) were benign and 36 (23.1 %) malignant. Maximum stiffness (Emax) with a cut-off of 82.3 kPa had the highest area under the receiver operating characteristics curve (Az) value compared with other SWE parameters, 0.860 (sensitivity 88.9 %, specificity 77.5 %, accuracy 80.1 %). Az values of conventional ultrasound combined with each SWE parameter showed lower (but not significantly) values than with conventional ultrasound alone. Maximum stiffness (82.3 kPa) provided the best diagnostic performance. However the overall diagnostic performance of ultrasound plus SWE was not significantly better than that of conventional ultrasound alone. • SWE offers new information over and above conventional breast ultrasound • Various SWE parameters were explored regarding distinction between benign and malignant lesions • An elasticity of 82.3 kPa appears optimal in differentiating solid breast masses • However, ultrasound plus SWE was not significantly better than conventional ultrasound alone.

  8. Tuning of the PI Controller Parameters of a PMSG Wind Turbine to Improve Control Performance under Various Wind Speeds

    Directory of Open Access Journals (Sweden)

    Yun-Su Kim

    2015-02-01

    Full Text Available This paper presents a method to seek the PI controller parameters of a PMSG wind turbine to improve control performance. Since operating conditions vary with the wind speed, therefore the PI controller parameters should be determined as a function of the wind speed. Small-signal modeling of a PMSG WT is implemented to analyze the stability under various operating conditions and with eigenvalues obtained from the small-signal model of the PMSG WT, which are coordinated by adjusting the PI controller parameters. The parameters to be tuned are chosen by investigating participation factors of state variables, which simplifies the problem by reducing the number of parameters to be tuned. The process of adjusting these PI controller parameters is carried out using particle swarm optimization (PSO. To characterize the improvements in the control method due to the PSO method of tuning the PI controller parameters, the PMSG WT is modeled using the MATLAB/SimPowerSystems libraries with the obtained PI controller parameters.

  9. Design Parameter Optimization of a Silicon-Based Grating Waveguide for Performance Improvement in Biochemical Sensor Application.

    Science.gov (United States)

    Hong, Yoo-Seung; Cho, Chun-Hyung; Sung, Hyuk-Kee

    2018-03-05

    We performed numerical analysis and design parameter optimization of a silicon-based grating waveguide refractive index (RI) sensor. The performance of the grating waveguide RI sensor was determined by the full-width at half-maximum (FWHM) and the shift in the resonance wavelength in the transmission spectrum. The transmission extinction, a major figure-of-merit of an RI sensor that reflects both FWHM and resonance shift performance, could be significantly improved by the proper determination of three major grating waveguide parameters: duty ratio, grating period, and etching depth. We analyzed the transmission characteristics of the grating waveguide under various design parameter conditions using a finite-difference time domain method. We achieved a transmission extinction improvement of >26 dB under a given bioenvironmental target change by the proper choice of the design procedure and parameters. This design procedure and choice of appropriate parameters would enable the widespread application of silicon-based grating waveguide in high-performance RI biochemical sensor.

  10. Effect Of Pyridoxine Injection In Japanese Quail Eggs On HATCHABILITY, Performance And Some Physiological Parameters

    International Nuclear Information System (INIS)

    ELSAYED, M.A.; WAKWAK, M.M.; MAHROSE, KH.M.

    2010-01-01

    The present study was carried out at the poultry farm found in the Nuclear Research Center, Atomic Energy Authority, Inshas, Sharkia Governorate, Egypt, during January 2009. A total number of two hundreds and seventy five quail eggs were used in an experiment of a completely randomized design to estimate hatchability percentage, chick weight at hatch, growth performance, some blood parameters and carcass traits of Japanese quails as affected by injecting their eggs with pyridoxine. Eggs were divided into 5 groups (55 eggs each); the first group (without injection) was served as control while the second group was injected in the width end of the egg with 500 μl saline. The third, fourth and fifth groups were injected in the width end of the Japanese quail eggs with 40, 80 and 120 μg pyridoxine, respectively, dissolved in 500 μl saline. Hatchability percentage, live body weight, daily body weight gain and some organ weights (liver, gizzard and heart) were studied. At the end of the experiment, blood samples were collected for analyses. It was observed that the groups of quail eggs received 120 μg pyridoxine injection recorded the highest hatchability percent. Chick weight at hatch was non-significantly affected by saline solution injection. The birds hatched from the groups of quail eggs received 120μg pyridoxine recorded the highest live body weight, especially during the 2 nd and 3 rd weeks of age. The daily body weight gain was significantly affected by pyridoxine injection only during the intervals of 1 to 2, 3 to 4 and from 1 to 6 weeks of age. Serum total protein, albumin and globulin concentrations were highly significantly elevated in the birds hatched from the groups of quail eggs received 120μg pyridoxine than other groups. Serum AST activity was highly significantly increased in the birds hatched from the groups of quail eggs received 40 μg pyridoxine than other groups while serum ALT activity and calcium concentration were non

  11. Haematological and biochemical parameters in Churra-da-Terra-Quente ewes from the northeast of Portugal Parâmetros hematológicos e bioquímicos de ovelhas da raça Churra da Terra Quente do nordeste de Portugal

    Directory of Open Access Journals (Sweden)

    I.R. Dias

    2010-04-01

    Full Text Available Hematological and biochemical parameters, including plasma electrolytes and thyroid hormones, were determined in 73 clinically healthy Churra-da-Terra-Quente ewes, a typical breed from the northeast of Portugal. The hemogram values were: erythrocytes 9.8±1.5×10(12/L; haemoglobin 118.1±19.1g/L; haematocrit 40.8±5.9%; leukocytes 5.7±1.8×10(9/L; and platelets 544.3±177.2×10(9/L. The thrombin time was 17.3±1.7 seconds. The values of biochemical parameters were: total protein 76.4±6.1g/L; glucose 2.87±0.60mmol/L; total cholesterol 1.65±0.33mmol/L; aspartate aminotransferase 155.9±49.2U/L; alanine aminotransferase 23.2±9.6U/L; γ-glutamyl transferase 48.0±18.7U/L; total alkaline phosphatase 121.6±76.1U/L; glutamate dehydrogenase 6.4±3.7U/L; urea 7.32±2.22mmol/L; creatinine 123.0±54.1μmol/L; total calcium 2.53±0.25mmol/L; phosphorus 2.10±0.46mmol/L; magnesium 1.01±0.09mmol/L; sodium 152.04±3.65mmol/L; potassium 4.7±0.4mmol/L; ionized calcium 1.32±0.07mmol/L; total thyroxine 111.75±42.29nmol/L; total triiodothyronine 1.01±0.28nmol/L; free T4 11.93±1.78pmol/L; free T3 4.22±1.33pmol/L; and thyroid-stimulating hormone 0.18±0.19μIU/mL. Although differences among the Churra-da-Terra-Quente breed and other breeds may occur, the hematological and biochemical parameters, plasma electrolytes, and thyroid hormones, for this indigenous breed, were generally situated within the reference intervals previously reported for sheep.Os valores hematológicos e bioquímicos, incluindo os eletrólitos plasmáticos e os hormônios da tireoide, foram determinados em 73 ovelhas, clinicamente saudáveis, da raça Churra da Terra Quente, raça ovina característica do nordeste de Portugal. Os valores obtidos para o hemograma foram: eritrócitos 9,8±1,5×10(12 /L; hemoglobina 118,1±19,1g/L; hematócrito 40,8±5,9%; leucócitos 5,7±1,8×10(9 /L e plaquetas 544,3±177,2×10(9/L. O tempo de trombina foi de 17,3±1,7 segundos. Os valores dos par

  12. TGLF Recalibration for ITER Standard Case Parameters FY2015: Theory and Simulation Performance Target Final Report

    International Nuclear Information System (INIS)

    Candy, J.

    2015-01-01

    This work was motivated by the observation, as early as 2008, that GYRO simulations of some ITER operating scenarios exhibited nonlinear zonal-flow generation large enough to effectively quench turbulence inside r /a ~ 0.5. This observation of flow-dominated, low-transport states persisted even as more accurate and comprehensive predictions of ITER profiles were made using the state-of-the-art TGLF transport model. This core stabilization is in stark contrast to GYRO-TGLF comparisons for modern-day tokamaks, for which GYRO and TGLF are typically in very close agreement. So, we began to suspect that TGLF needed to be generalized to include the effect of zonal-flow stabilization in order to be more accurate for the conditions of reactor simulations. While the precise cause of the GYRO-TGLF discrepancy for ITER parameters was not known, it was speculated that closeness to threshold in the absence of driven rotation, as well as electromagnetic stabilization, created conditions more sensitive the self-generated zonal-flow stabilization than in modern tokamaks. Need for nonlinear zonal-flow stabilization: To explore the inclusion of a zonal-flow stabilization mechanism in TGLF, we started with a nominal ITER profile predicted by TGLF, and then performed linear and nonlinear GYRO simulations to characterize the behavior at and slightly above the nominal temperature gradients for finite levels of energy transport. Then, we ran TGLF on these cases to see where the discrepancies were largest. The predicted ITER profiles were indeed near to the TGLF threshold over most of the plasma core in the hybrid discharge studied (weak magnetic shear, q > 1). Scanning temperature gradients above the TGLF power balance values also showed that TGLF overpredicted the electron energy transport in the low-collisionality ITER plasma. At first (in Q3), a model of only the zonal-flow stabilization (Dimits shift) was attempted. Although we were able to construct an ad hoc model of the zonal

  13. TGLF Recalibration for ITER Standard Case Parameters FY2015: Theory and Simulation Performance Target Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Candy, J. [General Atomics, San Diego, CA (United States)

    2015-12-01

    This work was motivated by the observation, as early as 2008, that GYRO simulations of some ITER operating scenarios exhibited nonlinear zonal-flow generation large enough to effectively quench turbulence inside r /a ~ 0.5. This observation of flow-dominated, low-transport states persisted even as more accurate and comprehensive predictions of ITER profiles were made using the state-of-the-art TGLF transport model. This core stabilization is in stark contrast to GYRO-TGLF comparisons for modern-day tokamaks, for which GYRO and TGLF are typically in very close agreement. So, we began to suspect that TGLF needed to be generalized to include the effect of zonal-flow stabilization in order to be more accurate for the conditions of reactor simulations. While the precise cause of the GYRO-TGLF discrepancy for ITER parameters was not known, it was speculated that closeness to threshold in the absence of driven rotation, as well as electromagnetic stabilization, created conditions more sensitive the self-generated zonal-flow stabilization than in modern tokamaks. Need for nonlinear zonal-flow stabilization: To explore the inclusion of a zonal-flow stabilization mechanism in TGLF, we started with a nominal ITER profile predicted by TGLF, and then performed linear and nonlinear GYRO simulations to characterize the behavior at and slightly above the nominal temperature gradients for finite levels of energy transport. Then, we ran TGLF on these cases to see where the discrepancies were largest. The predicted ITER profiles were indeed near to the TGLF threshold over most of the plasma core in the hybrid discharge studied (weak magnetic shear, q > 1). Scanning temperature gradients above the TGLF power balance values also showed that TGLF overpredicted the electron energy transport in the low-collisionality ITER plasma. At first (in Q3), a model of only the zonal-flow stabilization (Dimits shift) was attempted. Although we were able to construct an ad hoc model of the zonal

  14. Incremental Diagnostic Performance of Combined Parameters in the Detection of Severe Coronary Artery Disease Using Exercise Gated Myocardial Perfusion Imaging.

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    Chia-Ju Liu

    Full Text Available Myocardial perfusion imaging (MPI using gated single-photon emission tomography (gSPECT may underestimate the severity of coronary artery disease (CAD. This study aimed to evaluate the significance of combined parameters derived from gSPECT, as well as treadmill stress test parameters, in the detection of severe CAD.A total of 211 consecutive patients referred for exercise MPI between June 2011 and June 2013 (who received invasive coronary angiography within six months after MPI were retrospectively reviewed. Exercise MPI was performed with Bruce protocol and 201Tl injected at peak exercise. Gated SPECT was performed using a cadmium-zinc-telluride camera and processed by QPS/QGS software. Perfusion defect abnormalities such as sum stress score (SSS; sum difference score, algorithm-derived total perfusion deficits, transient ischemic dilatation ratios of end-diastolic volumes and end-systolic volumes, post-stress changes in ejection fraction, and lung/heart ratio (LHR were calculated. Treadmill parameters, including ST depression (STD at the 1st and 3rd minutes of recovery stage (1'STD and 3'STD, maximal STD corrected by heart rate increment (ST/HR, heart rate decline in 1st and 3rd minutes of recovery stage, recovery heart rate ratio (HR ratio, systolic and mean blood pressure ratios (SBP ratio and MAP ratio during recovery phase were recorded. Diagnostic performances of these parameters were analyzed with receiver operating characteristic (ROC analysis and logistic regression for detection of left main (≥ 50% or 3-vessel disease (all ≥ 70% luminal stenosis on invasive angiography.Among various MPI and treadmill parameters used for detection of severe CAD, SSS and ST/HR had the highest AUC (0.78, 0.73, p = NS and best cut-off values (SSS > 6, ST/HR > 17.39 10-2mV/bpm, respectively. By univariate logistic regression, all parameters except 1'HRR, 3'HRR, SBP and MAP ratios increased the odds ratio of severe CAD. Only increased L/H ratio, 3'STD

  15. Optimization of machining parameters of turning operations based on multi performance criteria

    Directory of Open Access Journals (Sweden)

    N.K.Mandal

    2013-01-01

    Full Text Available The selection of optimum machining parameters plays a significant role to ensure quality of product, to reduce the manufacturing cost and to increase productivity in computer controlled manufacturing process. For many years, multi-objective optimization of turning based on inherent complexity of process is a competitive engineering issue. This study investigates multi-response optimization of turning process for an optimal parametric combination to yield the minimum power consumption, surface roughness and frequency of tool vibration using a combination of a Grey relational analysis (GRA. Confirmation test is conducted for the optimal machining parameters to validate the test result. Various turning parameters, such as spindle speed, feed and depth of cut are considered. Experiments are designed and conducted based on full factorial design of experiment.

  16. Association of Haematological and Radiological Findings with Clinical Outcome in Hospitalized Children 2-36 Months Old with Severe Lower Respiratory Tract Infection

    International Nuclear Information System (INIS)

    Waris, R.; Bhatti, N.; Nisar, Y. B.

    2016-01-01

    Background: Despite reduction in ld mortality during last decade, lower respiratory tract infection (LRTI) remained number one killer of under-five. The current study aimed to assess the association of haematological and radiological findings with clinical outcome in hospitalized children 2-36 months old with severe LRTI. Methods: In the current cross sectional study, 581 children 2-36 months old with severe LRTI were enrolled and followed at the Children Hospital, Islamabad, between 2011 and 2014. At the time of enrolment, complete history of present illness, anthropometric measurements, blood sample and chest radiograph were obtained. The primary outcome was either early clinical response (within 72 hours) or delayed clinical response (>72 hours). Multivariable logistic regression was performed to examine the association between haematological and radiological findings with clinical outcome, adjusted for potential confounding factors. Results: Of 581 enrolled children, 292 (50.3 percent) children had early, and 289 (49.7 percent) had delayed clinical response. The multivariable logistic regression showed that leucocytosis (OR 1.79, 95 percent CI 1.15-2.79), neutrophilia (OR 1.91, 95 percent CI 1.29-2.84), radiological interstitial pneumonia (OR 2.49, 95 percent CI 1.70-3.64), and lobar consolidation (OR 6.00, 95 percent CI 2.41-14.96) were significantly associated with delayed clinical response, after adjusted for potential confounding factors. Conclusions: Delayed clinical response was significantly associated with abnormal haematological and radiological findings at the time of admission in children 2-36 months old with severe LRTI. Haematological and radiological findings at the time of presentation are useful for predicting delayed clinical response in children 2-36 months old with severe LRTI. (author)

  17. Evaluating climate model performance with various parameter sets using observations over the recent past

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    M. F. Loutre

    2011-05-01

    Full Text Available Many sources of uncertainty limit the accuracy of climate projections. Among them, we focus here on the parameter uncertainty, i.e. the imperfect knowledge of the values of many physical parameters in a climate model. Therefore, we use LOVECLIM, a global three-dimensional Earth system model of intermediate complexity and vary several parameters within a range based on the expert judgement of model developers. Nine climatic parameter sets and three carbon cycle parameter sets are selected because they yield present-day climate simulations coherent with observations and they cover a wide range of climate responses to doubled atmospheric CO2 concentration and freshwater flux perturbation in the North Atlantic. Moreover, they also lead to a large range of atmospheric CO2 concentrations in response to prescribed emissions. Consequently, we have at our disposal 27 alternative versions of LOVECLIM (each corresponding to one parameter set that provide very different responses to some climate forcings. The 27 model versions are then used to illustrate the range of responses provided over the recent past, to compare the time evolution of climate variables over the time interval for which they are available (the last few decades up to more than one century and to identify the outliers and the "best" versions over that particular time span. For example, between 1979 and 2005, the simulated global annual mean surface temperature increase ranges from 0.24 °C to 0.64 °C, while the simulated increase in atmospheric CO2 concentration varies between 40 and 50 ppmv. Measurements over the same period indicate an increase in global annual mean surface temperature of 0.45 °C (Brohan et al., 2006 and an increase in atmospheric CO2 concentration of 44 ppmv (Enting et al., 1994; GLOBALVIEW-CO2, 2006. Only a few parameter sets yield simulations that reproduce the observed key variables of the climate system over the last

  18. A cluster of Candida krusei infections in a haematological unit

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    Vuopio-Varkila Jaana

    2007-08-01

    Full Text Available Abstract Background Candida krusei infections are associated with high mortality. In order to explore ways to prevent these infections, we investigated potential routes for nosocomial spread and possible clonality of C. krusei in a haematological unit which had experienced an unusually high incidence of cases. Methods We searched for C. krusei contamination of the hospital environment and determined the level of colonization in patients and health care workers. We also analyzed the possible association between exposure to prophylactic antifungals or chemotherapeutic agents and occurrence of C. krusei. The C. krusei isolates found were genotyped by pulsed-field electrophoresis method in order to determine possible relatedness of the cases. Results Twelve patients with invasive C. krusei infection and ten patients with potentially significant infection or mucosal colonization were documented within nine months. We were unable to identify any exogenic source of infection or colonization. Genetic analysis of the isolates showed little evidence of clonal transmission of C. krusei strains between the patients. Instead, each patient was colonized or infected by several different closely related genotypes. No association between medications and occurrence of C. krusei was found. Conclusion Little evidence of nosocomial spread of a single C. krusei clone was found. The outbreak may have been controlled by cessation of prophylactic antifungals and by intensifying infection control measures, e.g. hand hygiene and cohorting of the patients, although no clear association with these factors was demonstrated.

  19. Curriculum Design of a Flipped Classroom to Enhance Haematology Learning

    Science.gov (United States)

    Porcaro, Pauline A.; Jackson, Denise E.; McLaughlin, Patricia M.; O'Malley, Cindy J.

    2016-06-01

    A common trend in higher education is the "flipped" classroom, which facilitates active learning during class. The flipped approach to teaching was instituted in a haematology `major' class and the students' attitudes and preferences for the teaching materials were surveyed. The curriculum design was explicit and involved four major components (1) the preparation of the students; (2) the weekly pre-class work; (3) the in-class active learning strategies and (4) closing the learning loop using formative quizzes. Each of these components is discussed in detail and was informed by sound pedagogical strategies. Several different sources of information and several freely available software tools to engage the students are discussed. Two iterations are reported here, with improved pass rate for the final examination from 47 to 48 % in the traditional class to 56-65 % in the flipped classroom approach. The majority of students (93 and 89 %) came to the class prepared, after viewing the screencasts and engaged fully with the activities within the face-to-face time. The students perceived that solving case studies (93 %) was the most beneficial activity for their learning and this was closely followed by the production of essay plans (71 %). The majority of students recommended that this approach be repeated the following year (69 and 75 %).

  20. Avascular necrosis after chemotherapy for haematological malignancy in childhood.

    Science.gov (United States)

    Salem, K H; Brockert, A-K; Mertens, R; Drescher, W

    2013-12-01

    Avascular necrosis (AVN) is a serious complication of high-dose chemotherapy for haematological malignancy in childhood. In order to describe its incidence and main risk factors and to evaluate the current treatment options, we reviewed 105 children with a mean age of 8.25 years (1 to 17.8) who had acute lymphoblastic or acute myeloid leukaemia, or a non-Hodgkin's lymphoma. Overall, eight children (7.6%) developed AVN after a mean of 16.8 months (8 to 49). There were four boys and four girls with a mean age of 14.4 years (9.8 to 16.8) and a total of 18 involved sites, 12 of which were in the femoral head. All these children were aged > nine years (p < 0.001). All had received steroid treatment with a mean cumulative dose of prednisone of 5967 mg (4425 to 9599) compared with a mean of 3943 mg (0 to 18 585) for patients without AVN (p = 0.005). No difference existed between genders and no thrombophilic disorders were identified. Their initial treatment included 11 core decompressions and two bipolar hip replacements. Later, two salvage osteotomies were done and three patients (four hips) eventually needed a total joint replacement. We conclude that AVN mostly affects the weight-bearing epiphyses. Its risk increases with age and higher steroid doses. These high-risk patients may benefit from early screening for AVN.