WorldWideScience

Sample records for pattern forming method

  1. Selective laser pyrolysis of metallo-organics as a method of forming patterned thin film superconductors

    International Nuclear Information System (INIS)

    Mantese, J.V.; Catalan, A.B.; Sell, J.A.; Meyer, M.S.; Mance, A.M.

    1990-01-01

    This patent describes a method for forming patterned films of superconductive materials forming a solution from the neodecanoates of yttrium, barium and copper. The neodecanoates forming an oxide mixture exhibiting superconductive properties upon subsequent thermal decompositions wherein the oxide mixture is characterized by a ratio of yttrium:barium:copper of approximately 1:2:4, the solution comprising an organic solvent such as xylene; adding to the solution an appropriate dye, depositing a film of the solution having the dye onto a strontium titanate substrate; exposing selective regions of the film with an Argon laser emitting the wavelength of light, such that the exposed regions of the film become insoluble in the xylene; immersing the film into the xylene so that the soluble; unexposed regions of the film are removed from the substrate; heating the film to thermally decompose the neodecanoates into a film containing yttrium, barium and copper oxides; to promote recrystallization and grain growth of the metal oxides within the film and induce a change therein by which the film exhibits superconducting properties

  2. Long-time integration methods for mesoscopic models of pattern-forming systems

    International Nuclear Information System (INIS)

    Abukhdeir, Nasser Mohieddin; Vlachos, Dionisios G.; Katsoulakis, Markos; Plexousakis, Michael

    2011-01-01

    Spectral methods for simulation of a mesoscopic diffusion model of surface pattern formation are evaluated for long simulation times. Backwards-differencing time-integration, coupled with an underlying Newton-Krylov nonlinear solver (SUNDIALS-CVODE), is found to substantially accelerate simulations, without the typical requirement of preconditioning. Quasi-equilibrium simulations of patterned phases predicted by the model are shown to agree well with linear stability analysis. Simulation results of the effect of repulsive particle-particle interactions on pattern relaxation time and short/long-range order are discussed.

  3. Mandibulary dental arch form differences between level four polynomial method and pentamorphic pattern for normal occlusion sample

    Directory of Open Access Journals (Sweden)

    Y. Yuliana

    2011-07-01

    Full Text Available The aim of an orthodontic treatment is to achieve aesthetic, dental health and the surrounding tissues, occlusal functional relationship, and stability. The success of an orthodontic treatment is influenced by many factors, such as diagnosis and treatment plan. In order to do a diagnosis and a treatment plan, medical record, clinical examination, radiographic examination, extra oral and intra oral photos, as well as study model analysis are needed. The purpose of this study was to evaluate the differences in dental arch form between level four polynomial and pentamorphic arch form and to determine which one is best suitable for normal occlusion sample. This analytic comparative study was conducted at Faculty of Dentistry Universitas Padjadjaran on 13 models by comparing the dental arch form using the level four polynomial method based on mathematical calculations, the pattern of the pentamorphic arch and mandibular normal occlusion as a control. The results obtained were tested using statistical analysis T student test. The results indicate a significant difference both in the form of level four polynomial method and pentamorphic arch form when compared with mandibular normal occlusion dental arch form. Level four polynomial fits better, compare to pentamorphic arch form.

  4. Method for forming ammonia

    Science.gov (United States)

    Kong, Peter C.; Pink, Robert J.; Zuck, Larry D.

    2008-08-19

    A method for forming ammonia is disclosed and which includes the steps of forming a plasma; providing a source of metal particles, and supplying the metal particles to the plasma to form metal nitride particles; and providing a substance, and reacting the metal nitride particles with the substance to produce ammonia, and an oxide byproduct.

  5. Method for forming materials

    Science.gov (United States)

    Tolle, Charles R [Idaho Falls, ID; Clark, Denis E [Idaho Falls, ID; Smartt, Herschel B [Idaho Falls, ID; Miller, Karen S [Idaho Falls, ID

    2009-10-06

    A material-forming tool and a method for forming a material are described including a shank portion; a shoulder portion that releasably engages the shank portion; a pin that releasably engages the shoulder portion, wherein the pin defines a passageway; and a source of a material coupled in material flowing relation relative to the pin and wherein the material-forming tool is utilized in methodology that includes providing a first material; providing a second material, and placing the second material into contact with the first material; and locally plastically deforming the first material with the material-forming tool so as mix the first material and second material together to form a resulting material having characteristics different from the respective first and second materials.

  6. Densified waste form and method for forming

    Science.gov (United States)

    Garino, Terry J.; Nenoff, Tina M.; Sava Gallis, Dorina Florentina

    2015-08-25

    Materials and methods of making densified waste forms for temperature sensitive waste material, such as nuclear waste, formed with low temperature processing using metallic powder that forms the matrix that encapsulates the temperature sensitive waste material. The densified waste form includes a temperature sensitive waste material in a physically densified matrix, the matrix is a compacted metallic powder. The method for forming the densified waste form includes mixing a metallic powder and a temperature sensitive waste material to form a waste form precursor. The waste form precursor is compacted with sufficient pressure to densify the waste precursor and encapsulate the temperature sensitive waste material in a physically densified matrix.

  7. Methods for forming particles

    Science.gov (United States)

    Fox, Robert V.; Zhang, Fengyan; Rodriguez, Rene G.; Pak, Joshua J.; Sun, Chivin

    2016-06-21

    Single source precursors or pre-copolymers of single source precursors are subjected to microwave radiation to form particles of a I-III-VI.sub.2 material. Such particles may be formed in a wurtzite phase and may be converted to a chalcopyrite phase by, for example, exposure to heat. The particles in the wurtzite phase may have a substantially hexagonal shape that enables stacking into ordered layers. The particles in the wurtzite phase may be mixed with particles in the chalcopyrite phase (i.e., chalcopyrite nanoparticles) that may fill voids within the ordered layers of the particles in the wurtzite phase thus produce films with good coverage. In some embodiments, the methods are used to form layers of semiconductor materials comprising a I-III-VI.sub.2 material. Devices such as, for example, thin-film solar cells may be fabricated using such methods.

  8. Standardized waste form test methods

    International Nuclear Information System (INIS)

    Slate, S.C.

    1984-11-01

    The Materials Characterization Center (MCC) is developing standard tests to characterize nuclear waste forms. Development of the first thirteen tests was originally initiated to provide data to compare different high-level waste (HLW) forms and to characterize their basic performance. The current status of the first thirteen MCC tests and some sample test results is presented: The radiation stability tests (MCC-6 and 12) and the tensile-strength test (MCC-11) are approved; the static leach tests (MCC-1, 2, and 3) are being reviewed for full approval; the thermal stability (MCC-7) and microstructure evaluation (MCC-13) methods are being considered for the first time; and the flowing leach tests methods (MCC-4 and 5), the gas generation methods (MCC-8 and 9), and the brittle fracture method (MCC-10) are indefinitely delayed. Sample static leach test data on the ARM-1 approved reference material are presented. Established tests and proposed new tests will be used to meet new testing needs. For waste form production, tests on stability and composition measurement are needed to provide data to ensure waste form quality. In transportation, data are needed to evaluate the effects of accidents on canisterized waste forms. The new MCC-15 accident test method and some data are presented. Compliance testing needs required by the recent draft repository waste acceptance specifications are described. These specifications will control waste form contents, processing, and performance. 2 references, 2 figures

  9. Standardized waste form test methods

    International Nuclear Information System (INIS)

    Slate, S.C.

    1984-01-01

    The Materials Characterization Center (MCC) is developing standard tests to characterize nuclear waste forms. Development of the first thirteen tests was originally initiated to provide data to compare different high-level waste (HLW) forms and to characterize their basic performance. The current status of the first thirteen MCC tests and some sample test results are presented: the radiation stability tests (MCC-6 and 12) and the tensile-strength test (MCC-11) are approved; the static leach tests (MCC-1, 2, and 3) are being reviewed for full approval; the thermal stability (MCC-7) and microstructure evaluation (MCC-13) methods are being considered for the first time; and the flowing leach test methods (MCC-4 and 5), the gas generation methods (MCC-8 and 9), and the brittle fracture method (MCC-10) are indefinitely delayed. Sample static leach test data on the ARM-1 approved reference material are presented. Established tests and proposed new tests will be used to meet new testing needs. For waste form production, tests on stability and composition measurement are needed to provide data to ensure waste form quality. In transporation, data are needed to evaluate the effects of accidents on canisterized waste forms. The new MCC-15 accident test method and some data are presented. Compliance testing needs required by the recent draft repository waste acceptance specifications are described. These specifications will control waste form contents, processing, and performance

  10. Pattern recognition methods in air pollution control

    Energy Technology Data Exchange (ETDEWEB)

    Tauber, S

    1978-01-01

    The use of pattern recognition methods for predicting air pollution developments is discussed. Computer analysis of historical pollution data allows comparison in graphical form. An example of crisis prediction for carbon monoxide concentrations, using the pattern recognition method of analysis, is presented. Results of the analysis agreed well with actual CO conditions. (6 graphs, 4 references, 1 table)

  11. Method of fabricating patterned crystal structures

    KAUST Repository

    Yu, Liyang

    2016-12-15

    A method of manufacturing a patterned crystal structure for includes depositing an amorphous material. The amorphous material is modified such that a first portion of the amorphous thin-film layer has a first height/volume and a second portion of the amorphous thin-film layer has a second height/volume greater than the first portion. The amorphous material is annealed to induce crystallization, wherein crystallization is induced in the second portion first due to the greater height/volume of the second portion relative to the first portion to form patterned crystal structures.

  12. Effects of feed forms on growth pattern, behavioural responses and ...

    African Journals Online (AJOL)

    Effects of feed forms on growth pattern, behavioural responses and feacal microbial load ... load and behavioural activities (eating, drinking, physical pen interaction and ... Total organism counts varied significantly (p<0.05) with pigs on T1, T2, ...

  13. Biomimicry of Palm Tree Leaves Form and Pattern on Building Form

    Directory of Open Access Journals (Sweden)

    Agus Salim N.A.

    2014-01-01

    Full Text Available This article is a study on biomimicry of palm tree towards a building form. It is to find a suitable form and pattern that can be applied to building shell to ease building maintenance operation beside to enhance the aesthetic value of a building architecture. The research has been carried out by observation and modeling on some various species of palm tree’s patterns and forms. The result expectation can be found at the end of this research by producing the best pattern of palm tree that can be adapted to building envelop as the whole form of a building.

  14. Article and method of forming an article

    Science.gov (United States)

    Lacy, Benjamin Paul; Kottilingam, Srikanth Chandrudu; Dutta, Sandip; Schick, David Edward

    2017-12-26

    Provided are an article and a method of forming an article. The method includes providing a metallic powder, heating the metallic powder to a temperature sufficient to joint at least a portion of the metallic powder to form an initial layer, sequentially forming additional layers in a build direction by providing a distributed layer of the metallic powder over the initial layer and heating the distributed layer of the metallic powder, repeating the steps of sequentially forming the additional layers in the build direction to form a portion of the article having a hollow space formed in the build direction, and forming an overhang feature extending into the hollow space. The article includes an article formed by the method described herein.

  15. Spatiotemporal patterns formed by deformed adhesive in peeling

    International Nuclear Information System (INIS)

    Yamazaki, Yoshihiro; Toda, Akihiko

    2007-01-01

    Dynamical properties of peeling an adhesive tape are investigated experimentally as an analogy of sliding friction. An adhesive tape is peeled by pulling an elastic spring connected to the tape. Controlling its spring constant k and pulling speed V, peel force is measured and spatiotemporal patterns formed on the peeled tape by deformed adhesive are observed. It is found that there exist two kinds of adhesive state in peeling front. The emergence of multiple states is caused by the stability of a characteristic structure (tunnel structure) formed by deformed adhesive. Tunnel structures are distributed spatiotemporally on adhesive tape after peeling. Based on the spatiotemporal distribution, a morphology-dynamical phase diagram is constructed on k-V space and is divided into the four regions: (A) uniform pattern with tunnel structure, (B) uniform pattern without tunnel structure, (C) striped pattern with oscillatory peeling, and (D) spatiotemporally coexistent pattern

  16. Thermoelectric generator and method of forming same

    International Nuclear Information System (INIS)

    Wilson, K.T.

    1981-01-01

    A thermoelectric device is disclosed which comprises the formation of a multiplicity of thermocouples on a substrate in a narrow strip form, the thermocouples being formed by printing with first and second inks formed of suitable different powdered metals with a proper binder or flux. The thermocouples are formed in series and the opposed coupled areas are melted to form an intermingling of the two metals and the strips may be formed in substantial lengths and rolled onto a reel, or in relatively short strip form and disposed in a side-by-side abutting relationship in substantial numbers to define a generally rectangular panel form with opposed ends in electrical connection. The method of forming the panels includes the steps of feeding a suitable substrate, either in a continuous roll or sheet form, through first and second printers to form the series connected multiplicity of thermocouples thereon. From the printers the sheet or strip passes through a melter such as an induction furnace and from the furnace it passes through a sheeter, if the strip is in roll form. The sheets are then slit into narrow strips relative to the thermocouples, printed thereon and the strips are then formed into a bundle. A predetermined number of bundles are assembled into a panel form

  17. Photovoltaic cell module and method of forming

    Science.gov (United States)

    Howell, Malinda; Juen, Donnie; Ketola, Barry; Tomalia, Mary Kay

    2017-12-12

    A photovoltaic cell module, a photovoltaic array including at least two modules, and a method of forming the module are provided. The module includes a first outermost layer and a photovoltaic cell disposed on the first outermost layer. The module also includes a second outermost layer disposed on the photovoltaic cell and sandwiching the photovoltaic cell between the second outermost layer and the first outermost layer. The method of forming the module includes the steps of disposing the photovoltaic cell on the first outermost layer, disposing a silicone composition on the photovoltaic cell, and compressing the first outermost layer, the photovoltaic cell, and the second layer to form the photovoltaic cell module.

  18. Nanofiber electrode and method of forming same

    Energy Technology Data Exchange (ETDEWEB)

    Pintauro, Peter N.; Zhang, Wenjing

    2018-02-27

    In one aspect, a method of forming an electrode for an electrochemical device is disclosed. In one embodiment, the method includes the steps of mixing at least a first amount of a catalyst and a second amount of an ionomer or uncharged polymer to form a solution and delivering the solution into a metallic needle having a needle tip. The method further includes the steps of applying a voltage between the needle tip and a collector substrate positioned at a distance from the needle tip, and extruding the solution from the needle tip at a flow rate such as to generate electrospun fibers and deposit the generated fibers on the collector substrate to form a mat with a porous network of fibers. Each fiber in the porous network of the mat has distributed particles of the catalyst. The method also includes the step of pressing the mat onto a membrane.

  19. Single camera analyses in studying pattern forming dynamics of player interactions in team sports.

    OpenAIRE

    Duarte, Ricardo; Fernandes, Orlando; Folgado, Hugo; Araújo, Duarte

    2013-01-01

    A network of patterned interactions between players characterises team ball sports. Thus, interpersonal coordination patterns are an important topic in the study of performance in such sports. A very useful method has been the study of inter-individual interactions captured by a single camera filming an extended performance area. The appropriate collection of positional data allows investigating the pattern forming dynamics emerging in different performance sub-phases of team ball sports. Thi...

  20. Slab edge insulating form system and methods

    Science.gov (United States)

    Lee, Brain E [Corral de Tierra, CA; Barsun, Stephan K [Davis, CA; Bourne, Richard C [Davis, CA; Hoeschele, Marc A [Davis, CA; Springer, David A [Winters, CA

    2009-10-06

    A method of forming an insulated concrete foundation is provided comprising constructing a foundation frame, the frame comprising an insulating form having an opening, inserting a pocket former into the opening; placing concrete inside the foundation frame; and removing the pocket former after the placed concrete has set, wherein the concrete forms a pocket in the placed concrete that is accessible through the opening. The method may further comprise sealing the opening by placing a sealing plug or sealing material in the opening. A system for forming an insulated concrete foundation is provided comprising a plurality of interconnected insulating forms, the insulating forms having a rigid outer member protecting and encasing an insulating material, and at least one gripping lip extending outwardly from the outer member to provide a pest barrier. At least one insulating form has an opening into which a removable pocket former is inserted. The system may also provide a tension anchor positioned in the pocket former and a tendon connected to the tension anchor.

  1. Methods of forming semiconductor devices and devices formed using such methods

    Science.gov (United States)

    Fox, Robert V; Rodriguez, Rene G; Pak, Joshua

    2013-05-21

    Single source precursors are subjected to carbon dioxide to form particles of material. The carbon dioxide may be in a supercritical state. Single source precursors also may be subjected to supercritical fluids other than supercritical carbon dioxide to form particles of material. The methods may be used to form nanoparticles. In some embodiments, the methods are used to form chalcopyrite materials. Devices such as, for example, semiconductor devices may be fabricated that include such particles. Methods of forming semiconductor devices include subjecting single source precursors to carbon dioxide to form particles of semiconductor material, and establishing electrical contact between the particles and an electrode.

  2. Die singulation method and package formed thereby

    Science.gov (United States)

    Anderson, Robert C [Tucson, AZ; Shul, Randy J [Albuquerque, NM; Clews, Peggy J [Tijeras, NM; Baker, Michael S [Albuquerque, NM; De Boer, Maarten P [Albuquerque, NM

    2012-08-07

    A method is disclosed for singulating die from a substrate having a sacrificial layer and one or more device layers, with a retainer being formed in the device layer(s) and anchored to the substrate. Deep Reactive Ion Etching (DRIE) etching of a trench through the substrate from the bottom side defines a shape for each die. A handle wafer is then attached to the bottom side of the substrate, and the sacrificial layer is etched to singulate the die and to form a frame from the retainer and the substrate. The frame and handle wafer, which retain the singulated die in place, can be attached together with a clamp or a clip and to form a package for the singulated die. One or more stops can be formed from the device layer(s) to limit a sliding motion of the singulated die.

  3. Method of forming an HTS article

    Science.gov (United States)

    Bhattacharya, Raghu N.; Zhang, Xun; Selvamanickam, Venkat

    2014-08-19

    A method of forming a superconducting article includes providing a substrate tape, forming a superconducting layer overlying the substrate tape, and depositing a capping layer overlying the superconducting layer. The capping layer includes a noble metal and has a thickness not greater than about 1.0 micron. The method further includes electrodepositing a stabilizer layer overlying the capping layer using a solution that is non-reactive to the superconducting layer. The superconducting layer has an as-formed critical current I.sub.C(AF) and a post-stabilized critical current I.sub.C(PS). The I.sub.C(PS) is at least about 95% of the I.sub.C(AF).

  4. Method of forming aluminum oxynitride material and bodies formed by such methods

    Science.gov (United States)

    Bakas, Michael P [Ammon, ID; Lillo, Thomas M [Idaho Falls, ID; Chu, Henry S [Idaho Falls, ID

    2010-11-16

    Methods of forming aluminum oxynitride (AlON) materials include sintering green bodies comprising aluminum orthophosphate or another sacrificial material therein. Such green bodies may comprise aluminum, oxygen, and nitrogen in addition to the aluminum orthophosphate. For example, the green bodies may include a mixture of aluminum oxide, aluminum nitride, and aluminum orthophosphate or another sacrificial material. Additional methods of forming aluminum oxynitride (AlON) materials include sintering a green body including a sacrificial material therein, using the sacrificial material to form pores in the green body during sintering, and infiltrating the pores formed in the green body with a liquid infiltrant during sintering. Bodies are formed using such methods.

  5. Pre-form ceramic matrix composite cavity and method of forming and method of forming a ceramic matrix composite component

    Science.gov (United States)

    Monaghan, Philip Harold; Delvaux, John McConnell; Taxacher, Glenn Curtis

    2015-06-09

    A pre-form CMC cavity and method of forming pre-form CMC cavity for a ceramic matrix component includes providing a mandrel, applying a base ply to the mandrel, laying-up at least one CMC ply on the base ply, removing the mandrel, and densifying the base ply and the at least one CMC ply. The remaining densified base ply and at least one CMC ply form a ceramic matrix component having a desired geometry and a cavity formed therein. Also provided is a method of forming a CMC component.

  6. Implications of tristability in pattern-forming ecosystems

    Science.gov (United States)

    Zelnik, Yuval R.; Gandhi, Punit; Knobloch, Edgar; Meron, Ehud

    2018-03-01

    Many ecosystems show both self-organized spatial patterns and multistability of possible states. The combination of these two phenomena in different forms has a significant impact on the behavior of ecosystems in changing environments. One notable case is connected to tristability of two distinct uniform states together with patterned states, which has recently been found in model studies of dryland ecosystems. Using a simple model, we determine the extent of tristability in parameter space, explore its effects on the system dynamics, and consider its implications for state transitions or regime shifts. We analyze the bifurcation structure of model solutions that describe uniform states, periodic patterns, and hybrid states between the former two. We map out the parameter space where these states exist, and note how the different states interact with each other. We further focus on two special implications with ecological significance, breakdown of the snaking range and complex fronts. We find that the organization of the hybrid states within a homoclinic snaking structure breaks down as it meets a Maxwell point where simple fronts are stationary. We also discover a new series of complex fronts between the uniform states, each with its own velocity. We conclude with a brief discussion of the significance of these findings for the dynamics of regime shifts and their potential control.

  7. Numerical Methods for Plate Forming by Line Heating

    DEFF Research Database (Denmark)

    Clausen, Henrik Bisgaard

    2000-01-01

    Line heating is the process of forming originally flat plates into a desired shape by means of heat treatment. Parameter studies are carried out on a finite element model to provide knowledge of how the process behaves with varying heating conditions. For verification purposes, experiments are ca...... are carried out; one set of experiments investigates the actual heat flux distribution from a gas torch and another verifies the validty of the FE calculations. Finally, a method to predict the heating pattern is described....

  8. All-fiber maskless lithographic technology to form microcircular interference pattern on Azo polymer film

    Science.gov (United States)

    Kim, Junki; Jung, Yongmin; Oh, Kyunghwan; Chun, Chaemin; Hong, Jeachul; Kim, Dongyu

    2005-03-01

    We report a novel all-fiber, maskless lithograpic technology to form various concentric grating patterns for micro zone plate on azo polymer film. The proposed technology is based on the interference pattern out of the cleaved end of a coreless silica fiber (CSF)-single mode fiber (SMF) composite. The light guided along SMF expands into the CSF segment to generate various circular interference patterns depending on the length of CSF. Interference patterns are experimentally observed when the CSF length is over a certain length and the finer spacing between the concentric rings are obtained for a longer CSF. By using beam propagation method (BPM) package, we could further investigated the concentric interference patterns in terms of intensity distribution and fringe spacing as a function of CSF length. These intereference patterns are directly projected over azo polymer film and their intensity distrubution formed surface relief grating (SRG) patterns. Compared to photoresist films azo polymer layers produce surface relief grating (SRG), where the actual mass of layer is modulated rather than refractive index. The geometric parameters of the CSF length as well as diameter and the spacing between the cleaved end of a CSF and azo polymer film, were found to play a major role to generate various concentric structures. With the demonstration of the circular SRG patterns, we confirmed that the proposed technique do have an ample potential to fabricate micro fresnel zone plate, that could find applications in lens arrays for optical beam formings as well as compact photonic devices.

  9. Comparison of validation methods for forming simulations

    Science.gov (United States)

    Schug, Alexander; Kapphan, Gabriel; Bardl, Georg; Hinterhölzl, Roland; Drechsler, Klaus

    2018-05-01

    The forming simulation of fibre reinforced thermoplastics could reduce the development time and improve the forming results. But to take advantage of the full potential of the simulations it has to be ensured that the predictions for material behaviour are correct. For that reason, a thorough validation of the material model has to be conducted after characterising the material. Relevant aspects for the validation of the simulation are for example the outer contour, the occurrence of defects and the fibre paths. To measure these features various methods are available. Most relevant and also most difficult to measure are the emerging fibre orientations. For that reason, the focus of this study was on measuring this feature. The aim was to give an overview of the properties of different measuring systems and select the most promising systems for a comparison survey. Selected were an optical, an eddy current and a computer-assisted tomography system with the focus on measuring the fibre orientations. Different formed 3D parts made of unidirectional glass fibre and carbon fibre reinforced thermoplastics were measured. Advantages and disadvantages of the tested systems were revealed. Optical measurement systems are easy to use, but are limited to the surface plies. With an eddy current system also lower plies can be measured, but it is only suitable for carbon fibres. Using a computer-assisted tomography system all plies can be measured, but the system is limited to small parts and challenging to evaluate.

  10. Method of forming a dianhydrosugar alcohol

    Science.gov (United States)

    Holladay, Johnathan E [Kennewick, WA; Hu, Jianli [Kennewick, WA; Wang, Yong [Richland, WA; Werpy, Todd A [West Richland, WA; Zhang, Xinjie [Burlington, MA

    2010-01-19

    The invention includes methods of producing dianhydrosugars. A polyol is reacted in the presence of a first catalyst to form a monocyclic sugar. The monocyclic sugar is transferred to a second reactor where it is converted to a dianhydrosugar alcohol in the presence of a second catalyst. The invention includes a process of forming isosorbide. An initial reaction is conducted at a first temperature in the presence of a solid acid catalyst. The initial reaction involves reacting sorbitol to produce 1,4-sorbitan, 3,6-sorbitan, 2,5-mannitan and 2,5-iditan. Utilizing a second temperature, the 1,4-sorbitan and 3,6-sorbitan are converted to isosorbide. The invention includes a method of purifying isosorbide from a mixture containing isosorbide and at least one additional component. A first distillation removes a first portion of the isosorbide from the mixture. A second distillation is then conducted at a higher temperature to remove a second portion of isosorbide from the mixture.

  11. METHODS OF FORMING THE STRUCTURE OF KNOWLEDGE

    Directory of Open Access Journals (Sweden)

    Tatyana A. Snegiryova

    2015-01-01

    Full Text Available The aim of the study is to describe the method of forming thestructure of knowledge of students on the basis of an integrated approach (expert, taxonomy and thesaurus and the presentation of the results of its use in the study of medical and biological physics at the Izhevsk State Medical Academy.Methods. The methods used in the work involve: an integrated approach that includes group expert method, developed by V. S. Cherepanov; taxonomy and thesaurus approach when creating a model of taxonomic structure of knowledge, as well as models of the formation of the knowledge structure.Results. The algorithm, stages and procedures of knowledge structure formation of trainees are considered in detail; the model of the given process is created; the technology of content selection of a teaching material due to the fixed time that has been released on studying of concrete discipline is shown.Scientific novelty and practical significance. Advantage of the proposed method and model of students’ knowledge structure formation consists in their flexibility: at certain adaptation they can be used while training to any discipline apart of its specificity and educational institution. Observance of all stages of the presented technology of content selection of a teaching material on the basis of an expert estimation will promote substantial increase of quality of training; make it possible to develop the unified method uniting the various points of view of teachers on knowledge formation of trainees.

  12. Capacitor assembly and related method of forming

    Science.gov (United States)

    Zhang, Lili; Tan, Daniel Qi; Sullivan, Jeffrey S.

    2017-12-19

    A capacitor assembly is disclosed. The capacitor assembly includes a housing. The capacitor assembly further includes a plurality of capacitors disposed within the housing. Furthermore, the capacitor assembly includes a thermally conductive article disposed about at least a portion of a capacitor body of the capacitors, and in thermal contact with the capacitor body. Moreover, the capacitor assembly also includes a heat sink disposed within the housing and in thermal contact with at least a portion of the housing and the thermally conductive article such that the heat sink is configured to remove heat from the capacitor in a radial direction of the capacitor assembly. Further, a method of forming the capacitor assembly is also presented.

  13. Improved pattern recognition systems by hybrid methods

    International Nuclear Information System (INIS)

    Duerr, B.; Haettich, W.; Tropf, H.; Winkler, G.; Fraunhofer-Gesellschaft zur Foerderung der Angewandten Forschung e.V., Karlsruhe

    1978-12-01

    This report describes a combination of statistical and syntactical pattern recongition methods. The hierarchically structured recognition system consists of a conventional statistical classifier, a structural classifier analysing the topological composition of the patterns, a stage reducing the number of hypotheses made by the first two stages, and a mixed stage based on a search for maximum similarity between syntactically generated prototypes and patterns. The stages work on different principles to avoid mistakes made in one stage in the other stages. This concept is applied to the recognition of numerals written without constraints. If no samples are rejected, a recognition rate of 99,5% is obtained. (orig.) [de

  14. Method of forming composite fiber blends

    Science.gov (United States)

    McMahon, Paul E. (Inventor); Chung, Tai-Shung (Inventor); Ying, Lincoln (Inventor)

    1989-01-01

    The instant invention involves a process used in preparing fibrous tows which may be formed into polymeric plastic composites. The process involves the steps of (a) forming a tow of strong filamentary materials; (b) forming a thermoplastic polymeric fiber; (c) intermixing the two tows; and (d) withdrawing the intermixed tow for further use.

  15. Elevated temperature forming method and preheater apparatus

    Science.gov (United States)

    Krajewski, Paul E; Hammar, Richard Harry; Singh, Jugraj; Cedar, Dennis; Friedman, Peter A; Luo, Yingbing

    2013-06-11

    An elevated temperature forming system in which a sheet metal workpiece is provided in a first stage position of a multi-stage pre-heater, is heated to a first stage temperature lower than a desired pre-heat temperature, is moved to a final stage position where it is heated to a desired final stage temperature, is transferred to a forming press, and is formed by the forming press. The preheater includes upper and lower platens that transfer heat into workpieces disposed between the platens. A shim spaces the upper platen from the lower platen by a distance greater than a thickness of the workpieces to be heated by the platens and less than a distance at which the upper platen would require an undesirably high input of energy to effectively heat the workpiece without being pressed into contact with the workpiece.

  16. Lubricant Test Methods for Sheet Metal Forming

    DEFF Research Database (Denmark)

    Bay, Niels; Olsson, David Dam; Andreasen, Jan Lasson

    2008-01-01

    appearing in different sheet forming operations such as stretch forming, deep drawing, ironing and punching. The laboratory tests have been especially designed to model the conditions in industrial production. Application of the tests for evaluating new lubricants before introducing them in production has......Sheet metal forming of tribologically difficult materials such as stainless steel, Al-alloys and Ti-alloys or forming in tribologically difficult operations like ironing, punching or deep drawing of thick plate requires often use of environmentally hazardous lubricants such as chlorinated paraffin...... oils in order to avoid galling. The present paper describes a systematic research in the development of new, environmentally harmless lubricants focusing on the lubricant testing aspects. A system of laboratory tests has been developed to study the lubricant performance under the very varied conditions...

  17. A method for predicting monthly rainfall patterns

    International Nuclear Information System (INIS)

    Njau, E.C.

    1987-11-01

    A brief survey is made of previous methods that have been used to predict rainfall trends or drought spells in different parts of the earth. The basic methodologies or theoretical strategies used in these methods are compared with contents of a recent theory of Sun-Weather/Climate links (Njau, 1985a; 1985b; 1986; 1987a; 1987b; 1987c) which point towards the possibility of practical climatic predictions. It is shown that not only is the theoretical basis of each of these methodologies or strategies fully incorporated into the above-named theory, but also this theory may be used to develop a technique by which future monthly rainfall patterns can be predicted in further and finer details. We describe the latter technique and then illustrate its workability by means of predictions made on monthly rainfall patterns in some East African meteorological stations. (author). 43 refs, 11 figs, 2 tabs

  18. Method and Apparatus for Forming Nanodroplets

    Science.gov (United States)

    Ackley, Donald; Forster, Anita

    2011-01-01

    This innovation uses partially miscible fluids to form nano- and microdroplets in a microfluidic droplet generator system. Droplet generators fabricated in PDMS (polydimethylsiloxane) are currently being used to fabricate engineered nanoparticles and microparticles. These droplet generators were first demonstrated in a T-junction configuration, followed by a cross-flow configuration. All of these generating devices have used immiscible fluids, such as oil and water. This immiscible fluid system can produce mono-dispersed distributions of droplets and articles with sizes ranging from a few hundred nanometers to a few hundred microns. For applications such as drug delivery, the ability to encapsulate aqueous solutions of drugs within particles formed from the droplets is desirable. Of particular interest are non-polar solvents that can dissolve lipids for the formation of liposomes in the droplet generators. Such fluids include ether, cyclohexane, butanol, and ethyl acetate. Ethyl acetate is of particular interest for two reasons. It is relatively nontoxic and it is formed from ether and acetic acid, and maybe broken down into its constituents at relatively low concentrations.

  19. Programmable assembly of pressure sensors using pattern-forming bacteria.

    Science.gov (United States)

    Cao, Yangxiaolu; Feng, Yaying; Ryser, Marc D; Zhu, Kui; Herschlag, Gregory; Cao, Changyong; Marusak, Katherine; Zauscher, Stefan; You, Lingchong

    2017-11-01

    Biological systems can generate microstructured materials that combine organic and inorganic components and possess diverse physical and chemical properties. However, these natural processes in materials fabrication are not readily programmable. Here, we use a synthetic-biology approach to assemble patterned materials. We demonstrate programmable fabrication of three-dimensional (3D) materials by printing engineered self-patterning bacteria on permeable membranes that serve as a structural scaffold. Application of gold nanoparticles to the colonies creates hybrid organic-inorganic dome structures. The dynamics of the dome structures' response to pressure is determined by their geometry (colony size, dome height, and pattern), which is easily modified by varying the properties of the membrane (e.g., pore size and hydrophobicity). We generate resettable pressure sensors that process signals in response to varying pressure intensity and duration.

  20. Advanced method for making vitreous waste forms

    International Nuclear Information System (INIS)

    Pope, J.M.; Harrison, D.E.

    1980-01-01

    A process is described for making waste glass that circumvents the problems of dissolving nuclear waste in molten glass at high temperatures. Because the reactive mixing process is independent of the inherent viscosity of the melt, any glass composition can be prepared with equal facility. Separation of the mixing and melting operations permits novel glass fabrication methods to be employed

  1. Method for forming polymerized microfluidic devices

    Science.gov (United States)

    Sommer, Gregory J.; Hatch, Anson V.; Wang, Ying-Chih; Singh, Anup K.; Renzi, Ronald F.; Claudnic, Mark R.

    2013-03-12

    Methods for making a microfluidic device according to embodiments of the present invention include defining.about.cavity. Polymer precursor solution is positioned in the cavity, and exposed to light to begin the polymerization process and define a microchannel. In some embodiments, after the polymerization process is partially complete, a solvent rinse is performed, or fresh polymer precursor introduced into the microchannel. This may promote removal of unpolymerized material from the microchannel and enable smaller feature sizes. The polymer precursor solution may contain an iniferter. Polymerized features therefore may be capped with the iniferter, which is photoactive. The iniferter may aid later binding of a polyacrylamide gel to the microchannel surface.

  2. Advanced Pattern Recognition Techniques (Techniques avancees de reconnaissance de forme)

    Science.gov (United States)

    1998-09-01

    alarmes dans la d6tection des mines terrestres et des munitions explosives non explos6es. Les m~thodes classiques de reconnaissance de forme...the XVIII. Congress of the International Society for [19] DIN EN 60825-1(IEC 825-1) VDE 0837, Photogrammetry and Remote Sensing Sicherheit von Laser

  3. The startle pattern in the minor form of hyperekplexia

    NARCIS (Netherlands)

    Tijssen, M. A.; Padberg, G. W.; van Dijk, J. G.

    1996-01-01

    BACKGROUND: The major and minor forms of hereditary hyperekplexia (HE) are characterized by excessive startle responses, which are accompanied by transient stiffness only in major HE; patients with major HE also have continuous stiffness during infancy. A point mutation has been identified for major

  4. Influence of time and pressure of forming a pattern on mechanical properties

    Directory of Open Access Journals (Sweden)

    T. Pacyniak

    2011-07-01

    Full Text Available In this paper, the technology of forming patterns on a research station equipped with an autoclave A-600 of Polish company GROM is presented. This study was conducted to determine the influence of pressure and time of forming a pattern on the bending strength. Analysis of the results confirmed that bending strength increases with increasing the pressure. The time of forming a pattern has a similar effect.

  5. Growth of large patterned arrays of neurons using plasma methods

    International Nuclear Information System (INIS)

    Brown, I G; Bjornstad, K A; Blakely, E A; Galvin, J E; Monteiro, O R; Sangyuenyongpipat, S

    2003-01-01

    To understand how large systems of neurons communicate, we need to develop, among other things, methods for growing patterned networks of large numbers of neurons. Success with this challenge will be important to our understanding of how the brain works, as well as to the development of novel kinds of computer architecture that may parallel the organization of the brain. We have investigated the use of metal ion implantation using a vacuum-arc ion source, and plasma deposition with a filtered vacuum-arc system, as a means of forming regions of selective neuronal attachment on surfaces. Lithographic patterns created by the treating surface with ion species that enhance or inhibit neuronal cell attachment allow subsequent proliferation and/or differentiation of the neurons to form desired patterned neural arrays. In the work described here, we used glass microscope slides as substrates, and some of the experiments made use of simple masks to form patterns of ion beam or plasma deposition treated regions. PC-12 rat neurons were then cultured on the treated substrates coated with Type I Collagen, and the growth and differentiation was monitored. Particularly good selective growth was obtained using plasma deposition of diamond-like carbon films of about one hundred Angstroms thickness. Neuron proliferation and the elaboration of dendrites and axons after the addition of nerve growth factor both showed excellent contrast, with prolific growth and differentiation on the treated surfaces and very low growth on the untreated surfaces

  6. Growth of large patterned arrays of neurons using plasma methods

    Energy Technology Data Exchange (ETDEWEB)

    Brown, I G; Bjornstad, K A; Blakely, E A; Galvin, J E; Monteiro, O R; Sangyuenyongpipat, S [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States)

    2003-05-01

    To understand how large systems of neurons communicate, we need to develop, among other things, methods for growing patterned networks of large numbers of neurons. Success with this challenge will be important to our understanding of how the brain works, as well as to the development of novel kinds of computer architecture that may parallel the organization of the brain. We have investigated the use of metal ion implantation using a vacuum-arc ion source, and plasma deposition with a filtered vacuum-arc system, as a means of forming regions of selective neuronal attachment on surfaces. Lithographic patterns created by the treating surface with ion species that enhance or inhibit neuronal cell attachment allow subsequent proliferation and/or differentiation of the neurons to form desired patterned neural arrays. In the work described here, we used glass microscope slides as substrates, and some of the experiments made use of simple masks to form patterns of ion beam or plasma deposition treated regions. PC-12 rat neurons were then cultured on the treated substrates coated with Type I Collagen, and the growth and differentiation was monitored. Particularly good selective growth was obtained using plasma deposition of diamond-like carbon films of about one hundred Angstroms thickness. Neuron proliferation and the elaboration of dendrites and axons after the addition of nerve growth factor both showed excellent contrast, with prolific growth and differentiation on the treated surfaces and very low growth on the untreated surfaces.

  7. Methods for forming particles from single source precursors

    Science.gov (United States)

    Fox, Robert V [Idaho Falls, ID; Rodriguez, Rene G [Pocatello, ID; Pak, Joshua [Pocatello, ID

    2011-08-23

    Single source precursors are subjected to carbon dioxide to form particles of material. The carbon dioxide may be in a supercritical state. Single source precursors also may be subjected to supercritical fluids other than supercritical carbon dioxide to form particles of material. The methods may be used to form nanoparticles. In some embodiments, the methods are used to form chalcopyrite materials. Devices such as, for example, semiconductor devices may be fabricated that include such particles. Methods of forming semiconductor devices include subjecting single source precursors to carbon dioxide to form particles of semiconductor material, and establishing electrical contact between the particles and an electrode.

  8. The One-Pot Directed Assembly of Cylinder-Forming Block Copolymer on Adjacent Chemical Patterns for Bimodal Patterning.

    Science.gov (United States)

    Chang, Tzu-Hsuan; Xiong, Shisheng; Liu, Chi-Chun; Liu, Dong; Nealey, Paul F; Ma, Zhenqiang

    2017-09-01

    The direct self-assembly of cylinder-forming poly(styrene-block-methyl-methacrylate) (PS-b-PMMA) block copolymer is successfully assembled into two orientations, according to the underlying guiding pattern in different areas. Lying-down and perpendicular cylinders are formed, respectively, depending on the design of chemical pattern: sparse line/space pattern or hexagonal dot array. The first chemical pattern composed of prepatterned cross-linked polystyrene (XPS) line/space structure has a period (L S ) equal to twice the intercylinder period of the block copolymer (L 0 ). The PS-b-PMMA thin film on the prepared chemical template after thermal annealing forms a lying-down cylinder morphology when the width of the PS strips is less than the width of PS block in the PS-b-PMMA block copolymer. The morphology is only applicable at the discrete thickness of the PS-b-PMMA film. In addition to forming the lying-down cylinders directly on the XPS guiding pattern, the cylinder-forming block copolymer can also be assembled in a perpendicular way on the second guiding pattern (the hexagonal dot array). The block copolymer films are registered into two orientations in a single directed self-assembly process. The features of the assembled patterns are successfully transferred down to the silicon oxide substrate. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. Data and statistical methods for analysis of trends and patterns

    International Nuclear Information System (INIS)

    Atwood, C.L.; Gentillon, C.D.; Wilson, G.E.

    1992-11-01

    This report summarizes topics considered at a working meeting on data and statistical methods for analysis of trends and patterns in US commercial nuclear power plants. This meeting was sponsored by the Office of Analysis and Evaluation of Operational Data (AEOD) of the Nuclear Regulatory Commission (NRC). Three data sets are briefly described: Nuclear Plant Reliability Data System (NPRDS), Licensee Event Report (LER) data, and Performance Indicator data. Two types of study are emphasized: screening studies, to see if any trends or patterns appear to be present; and detailed studies, which are more concerned with checking the analysis assumptions, modeling any patterns that are present, and searching for causes. A prescription is given for a screening study, and ideas are suggested for a detailed study, when the data take of any of three forms: counts of events per time, counts of events per demand, and non-event data

  10. Comorbid forms of psychopathology: key patterns and future research directions.

    Science.gov (United States)

    Cerdá, Magdalena; Sagdeo, Aditi; Galea, Sandro

    2008-01-01

    The purpose of this review is to systematically appraise the peer-reviewed literature about clustered forms of psychopathology and to present a framework that can be useful for studying comorbid psychiatric disorders. The review focuses on four of the most prevalent types of mental health problems: anxiety, depression, conduct disorder, and substance abuse. The authors summarize existing empirical research on the distribution of concurrent and sequential comorbidity in children and adolescents and in adults, and they review existing knowledge about exogenous risk factors that influence comorbidity. The authors include articles that used a longitudinal study design and used psychiatric definitions of the disorders. A total of 58 articles met the inclusion criteria and were assessed. Current evidence demonstrates a reciprocal, sequential relation between most comorbid pairs, although the mechanisms that mediate such links remain to be explained. Methodological concerns include the inconsistency of measurement of the disorders across studies, small sample sizes, and restricted follow-up times. Given the significant mental health burden placed by comorbid disorders, and their high prevalence across populations, research on the key risk factors for clustering of psychopathology is needed.

  11. Development of standard testing methods for nuclear-waste forms

    International Nuclear Information System (INIS)

    Mendel, J.E.; Nelson, R.D.

    1981-11-01

    Standard test methods for waste package component development and design, safety analyses, and licensing are being developed for the Nuclear Waste Materials Handbook. This paper describes mainly the testing methods for obtaining waste form materials data

  12. Methods of forming single source precursors, methods of forming polymeric single source precursors, and single source precursors and intermediate products formed by such methods

    Science.gov (United States)

    Fox, Robert V.; Rodriguez, Rene G.; Pak, Joshua J.; Sun, Chivin; Margulieux, Kelsey R.; Holland, Andrew W.

    2012-12-04

    Methods of forming single source precursors (SSPs) include forming intermediate products having the empirical formula 1/2{L.sub.2N(.mu.-X).sub.2M'X.sub.2}.sub.2, and reacting MER with the intermediate products to form SSPs of the formula L.sub.2N(.mu.-ER).sub.2M'(ER).sub.2, wherein L is a Lewis base, M is a Group IA atom, N is a Group IB atom, M' is a Group IIIB atom, each E is a Group VIB atom, each X is a Group VIIA atom or a nitrate group, and each R group is an alkyl, aryl, vinyl, (per)fluoro alkyl, (per)fluoro aryl, silane, or carbamato group. Methods of forming polymeric or copolymeric SSPs include reacting at least one of HE.sup.1R.sup.1E.sup.1H and MER with one or more substances having the empirical formula L.sub.2N(.mu.-ER).sub.2M'(ER).sub.2 or L.sub.2N(.mu.-X).sub.2M'(X).sub.2 to form a polymeric or copolymeric SSP. New SSPs and intermediate products are formed by such methods.

  13. Methods of forming single source precursors, methods of forming polymeric single source precursors, and single source precursors formed by such methods

    Science.gov (United States)

    Fox, Robert V.; Rodriguez, Rene G.; Pak, Joshua J.; Sun, Chivin; Margulieux, Kelsey R.; Holland, Andrew W.

    2014-09-09

    Methods of forming single source precursors (SSPs) include forming intermediate products having the empirical formula 1/2{L.sub.2N(.mu.-X).sub.2M'X.sub.2}.sub.2, and reacting MER with the intermediate products to form SSPs of the formula L.sub.2N(.mu.-ER).sub.2M'(ER).sub.2, wherein L is a Lewis base, M is a Group IA atom, N is a Group IB atom, M' is a Group IIIB atom, each E is a Group VIB atom, each X is a Group VIIA atom or a nitrate group, and each R group is an alkyl, aryl, vinyl, (per)fluoro alkyl, (per)fluoro aryl, silane, or carbamato group. Methods of forming polymeric or copolymeric SSPs include reacting at least one of HE.sup.1R.sup.1E.sup.1H and MER with one or more substances having the empirical formula L.sub.2N(.mu.-ER).sub.2M'(ER).sub.2 or L.sub.2N(.mu.-X).sub.2M'(X).sub.2 to form a polymeric or copolymeric SSP. New SSPs and intermediate products are formed by such methods.

  14. Methods of forming thermal management systems and thermal management methods

    Science.gov (United States)

    Gering, Kevin L.; Haefner, Daryl R.

    2012-06-05

    A thermal management system for a vehicle includes a heat exchanger having a thermal energy storage material provided therein, a first coolant loop thermally coupled to an electrochemical storage device located within the first coolant loop and to the heat exchanger, and a second coolant loop thermally coupled to the heat exchanger. The first and second coolant loops are configured to carry distinct thermal energy transfer media. The thermal management system also includes an interface configured to facilitate transfer of heat generated by an internal combustion engine to the heat exchanger via the second coolant loop in order to selectively deliver the heat to the electrochemical storage device. Thermal management methods are also provided.

  15. Possibilities of Particle Finite Element Methods in Industrial Forming Processes

    Science.gov (United States)

    Oliver, J.; Cante, J. C.; Weyler, R.; Hernandez, J.

    2007-04-01

    The work investigates the possibilities offered by the particle finite element method (PFEM) in the simulation of forming problems involving large deformations, multiple contacts, and new boundaries generation. The description of the most distinguishing aspects of the PFEM, and its application to simulation of representative forming processes, illustrate the proposed methodology.

  16. Effects Of Combinations Of Patternmaking Methods And Dress Forms On Garment Appearance

    Directory of Open Access Journals (Sweden)

    Fujii Chinami

    2017-09-01

    Full Text Available We investigated the effects of the combinations of patternmaking methods and dress forms on the appearance of a garment. Six upper garments were made using three patternmaking methods used in France, Italy, and Japan, and two dress forms made in Japan and France. The patterns and the appearances of the garments were compared using geometrical measurements. Sensory evaluations of the differences in garment appearance and fit on each dress form were also carried out. In the patterns, the positions of bust and waist darts were different. The waist dart length, bust dart length, and positions of the bust top were different depending on the patternmaking method, even when the same dress form was used. This was a result of differences in the measurements used and the calculation methods employed for other dimensions. This was because the ideal body shape was different for each patternmaking method. Even for garments produced for the same dress form, the appearances of the shoulder, bust, and waist from the front, side, and back views were different depending on the patternmaking method. As a result of the sensory evaluation, it was also found that the bust and waist shapes of the garments were different depending on the combination of patternmaking method and dress form. Therefore, to obtain a garment with better appearance, it is necessary to understand the effects of the combinations of patternmaking methods and body shapes.

  17. Externally controlled anisotropy in pattern-forming reaction-diffusion systems.

    Science.gov (United States)

    Escala, Dario M; Guiu-Souto, Jacobo; Muñuzuri, Alberto P

    2015-06-01

    The effect of centrifugal forces is analyzed in a pattern-forming reaction-diffusion system. Numerical simulations conducted on the appropriate extension of the Oregonator model for the Belousov-Zhabotinsky reaction show a great variety of dynamical behaviors in such a system. In general, the system exhibits an anisotropy that results in new types of patterns or in a global displacement of the previous one. We consider the effect of both constant and periodically modulated centrifugal forces on the different types of patterns that the system may exhibit. A detailed analysis of the patterns and behaviors observed for the different parameter values considered is presented here.

  18. Pattern recognition methods for acoustic emission analysis

    International Nuclear Information System (INIS)

    Doctor, P.G.; Harrington, T.P.; Hutton, P.H.

    1979-07-01

    Models have been developed that relate the rate of acoustic emissions to structural integrity. The implementation of these techniques in the field has been hindered by the noisy environment in which the data must be taken. Acoustic emissions from noncritical sources are recorded in addition to those produced by critical sources, such as flaws. A technique is discussed for prescreening acoustic events and filtering out those that are produced by noncritical sources. The methodology that was investigated is pattern recognition. Three different pattern recognition techniques were applied to a data set that consisted of acoustic emissions caused by crack growth and acoustic signals caused by extraneous noise sources. Examination of the acoustic emission data presented has uncovered several features of the data that can provide a reasonable filter. Two of the most valuable features are the frequency of maximum response and the autocorrelation coefficient at Lag 13. When these two features and several others were combined with a least squares decision algorithm, 90% of the acoustic emissions in the data set were correctly classified. It appears possible to design filters that eliminate extraneous noise sources from flaw-growth acoustic emissions using pattern recognition techniques

  19. Maximum super angle optimization method for array antenna pattern synthesis

    DEFF Research Database (Denmark)

    Wu, Ji; Roederer, A. G

    1991-01-01

    Different optimization criteria related to antenna pattern synthesis are discussed. Based on the maximum criteria and vector space representation, a simple and efficient optimization method is presented for array and array fed reflector power pattern synthesis. A sector pattern synthesized by a 2...

  20. A new method locating good glass-forming compositions

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Dechuan [Department of Materials Physics and Chemistry, Northeastern University, No.3-11, Wenhua Road, Shenyang, 110819 (China); Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, 72 Wenhua Road, Shenyang, 110016 (China); Geng, Yan [Department of Materials Physics and Chemistry, Northeastern University, No.3-11, Wenhua Road, Shenyang, 110819 (China); Li, Zhengkun [Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, 72 Wenhua Road, Shenyang, 110016 (China); Liu, Dingming [Department of Materials Physics and Chemistry, Northeastern University, No.3-11, Wenhua Road, Shenyang, 110819 (China); Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, 72 Wenhua Road, Shenyang, 110016 (China); Fu, Huameng; Zhu, Zhengwang [Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, 72 Wenhua Road, Shenyang, 110016 (China); Qi, Yang, E-mail: qiyang@imp.neu.edu.cn [Department of Materials Physics and Chemistry, Northeastern University, No.3-11, Wenhua Road, Shenyang, 110819 (China); Zhang, Haifeng, E-mail: hfzhang@imr.ac.cn [Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, 72 Wenhua Road, Shenyang, 110016 (China)

    2015-10-15

    A new method was proposed to pinpoint the compositions with good glass forming ability (GFA) by combining atomic clusters and mixing entropy. The clusters were confirmed by analyzing competing crystalline phases. The method was applied to the Zr–Al–Ni–Cu–Ag alloy system. A series of glass formers with diameter up to 20 mm were quickly detected in this system. The good glass formers were located only after trying 5 compositions around the calculated composition. The method was also effective in other multi-component systems. This method might provide a new way to understand glass formation and to quickly pinpoint compositions with high GFA. - Highlights: • A new method was proposed to quickly design glass formers with high glass forming ability. • The method of designing pentabasic Zr–Al–Ni–Cu–Ag alloys was applied. • A series of new Zr-based bulk metallic glasses with critical diameter of 20 mm were discovered.

  1. A new method locating good glass-forming compositions

    International Nuclear Information System (INIS)

    Yu, Dechuan; Geng, Yan; Li, Zhengkun; Liu, Dingming; Fu, Huameng; Zhu, Zhengwang; Qi, Yang; Zhang, Haifeng

    2015-01-01

    A new method was proposed to pinpoint the compositions with good glass forming ability (GFA) by combining atomic clusters and mixing entropy. The clusters were confirmed by analyzing competing crystalline phases. The method was applied to the Zr–Al–Ni–Cu–Ag alloy system. A series of glass formers with diameter up to 20 mm were quickly detected in this system. The good glass formers were located only after trying 5 compositions around the calculated composition. The method was also effective in other multi-component systems. This method might provide a new way to understand glass formation and to quickly pinpoint compositions with high GFA. - Highlights: • A new method was proposed to quickly design glass formers with high glass forming ability. • The method of designing pentabasic Zr–Al–Ni–Cu–Ag alloys was applied. • A series of new Zr-based bulk metallic glasses with critical diameter of 20 mm were discovered

  2. Effect of loading pattern on longitudinal bowing in flexible roll forming

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jae Hyun; Woo, Young Yun; Hwang, Tae Woo; Han, Sang Wook; Moon, Young Hoon [School of Mechanical Engineering, Engineering Research Center for Net Shape and Die Manufacturing, Pusan National University,Busan (Korea, Republic of)

    2016-12-15

    The flexible roll forming process can be used to fabricate products with a variable cross-section profile in the longitudinal direction. Transversal nonuniformity of the longitudinal strain is one of the fundamental characteristics of blank deformation in flexible roll forming. Longitudinal bowing is a shape defect caused by transversal nonuniformity of the longitudinal strain. In this study, loading patterns in flexible roll forming are investigated in order to reduce the longitudinal bowing in a roll-formed blank. To analyze the effects of loading patterns on longitudinal bowing, two different forming schedules are implemented. In schedule 1, loading patterns with different bending angle increments are designed under fixed initial and final bending angles. In schedule 2, loading patterns with different initial bending angles under the fixed final bending angle are designed. Our results show that the bowing heights are significantly affected by the loading patterns. The bowing susceptibilities vary with blank shape such as trapezoid, convex, and concave shapes. In addition to the peak longitudinal strain at the respective roll stands, the cumulative longitudinal strain from the initial to final stands is shown to be a reliable index in predicting the tendency of longitudinal bowing.

  3. Machine learning methods for clinical forms analysis in mental health.

    Science.gov (United States)

    Strauss, John; Peguero, Arturo Martinez; Hirst, Graeme

    2013-01-01

    In preparation for a clinical information system implementation, the Centre for Addiction and Mental Health (CAMH) Clinical Information Transformation project completed multiple preparation steps. An automated process was desired to supplement the onerous task of manual analysis of clinical forms. We used natural language processing (NLP) and machine learning (ML) methods for a series of 266 separate clinical forms. For the investigation, documents were represented by feature vectors. We used four ML algorithms for our examination of the forms: cluster analysis, k-nearest neigh-bours (kNN), decision trees and support vector machines (SVM). Parameters for each algorithm were optimized. SVM had the best performance with a precision of 64.6%. Though we did not find any method sufficiently accurate for practical use, to our knowledge this approach to forms has not been used previously in mental health.

  4. Carbon nanotubes and methods of forming same at low temperature

    Science.gov (United States)

    Biris, Alexandru S.; Dervishi, Enkeleda

    2017-05-02

    In one aspect of the invention, a method for growth of carbon nanotubes includes providing a graphitic composite, decorating the graphitic composite with metal nanostructures to form graphene-contained powders, and heating the graphene-contained powders at a target temperature to form the carbon nanotubes in an argon/hydrogen environment that is devoid of a hydrocarbon source. In one embodiment, the target temperature can be as low as about 150.degree. C. (.+-.5.degree. C.).

  5. Wittgenstein on Forms of Life, Patterns of Life, and Ways of Living

    Directory of Open Access Journals (Sweden)

    Daniele Moyal-Sharrock

    2015-10-01

    Full Text Available This paper aims to distinguish Wittgenstein’s concept of ‘form of life’ from other concepts or expressions that have been confused or conflated with it, such as ‘language-game’, ‘certainty’, ‘patterns of life’, ‘ways of living’ and ‘facts of living’. Competing interpretations of Wittgenstein’s ‘form(s of life’ are reviewed (Baker & Hacker, Cavell, Conway, Garver, and it is concluded that Wittgenstein intended both a singular and a plural use of the concept; with, where the human is concerned, a single human form of life characterized by innumerable forms of human life.

  6. Hollow fiber membranes and methods for forming same

    Science.gov (United States)

    Bhandari, Dhaval Ajit; McCloskey, Patrick Joseph; Howson, Paul Edward; Narang, Kristi Jean; Koros, William

    2016-03-22

    The invention provides improved hollow fiber membranes having at least two layers, and methods for forming the same. The methods include co-extruding a first composition, a second composition, and a third composition to form a dual layer hollow fiber membrane. The first composition includes a glassy polymer; the second composition includes a polysiloxane; and the third composition includes a bore fluid. The dual layer hollow fiber membranes include a first layer and a second layer, the first layer being a porous layer which includes the glassy polymer of the first composition, and the second layer being a polysiloxane layer which includes the polysiloxane of the second composition.

  7. A loading pattern optimization method for nuclear fuel management

    International Nuclear Information System (INIS)

    Argaud, J.P.

    1997-01-01

    Nuclear fuel reload of PWR core leads to the search of an optimal nuclear fuel assemblies distribution, namely of loading pattern. This large discrete optimization problem is here expressed as a cost function minimization. To deal with this problem, an approach based on gradient information is used to direct the search in the patterns discrete space. A method using an adjoint state formulation is then developed, and final results of complete patterns search tests by this method are presented. (author)

  8. Methods for detecting the environmental coccoid form of Helicobacter pylori

    Directory of Open Access Journals (Sweden)

    Mahnaz eMazaheri Assadi

    2015-05-01

    Full Text Available Helicobacter pylori is recognized as the most common pathogen to cause gastritis, peptic and duodenal ulcers, and gastric cancer. The organisms are found in two forms: 1 spiral-shaped bacillus and 2 coccoid. H. pylori coccoid form, generally found in the environment, is the transformed form of the normal spiral-shaped bacillus after exposed to water or adverse environmental conditions such as exposure to sub-inhibitory concentrations of antimicrobial agents. The putative infectious capability and the viability of H. pylori under environmental conditions are controversial. This disagreement is partially due to the fact of lack in detecting the coccoid form of H. pylori in the environment. Accurate and effective detection methods of H. pylori will lead to rapid treatment and disinfection, and less human health damages and reduction in health care costs. In this review, we provide a brief introduction to H. pylori environmental coccoid forms, their transmission and detection methods. We further discuss the use of these detection methods including their accuracy and efficiency.

  9. Flux form Semi-Lagrangian methods for parabolic problems

    Directory of Open Access Journals (Sweden)

    Bonaventura Luca

    2016-09-01

    Full Text Available A semi-Lagrangian method for parabolic problems is proposed, that extends previous work by the authors to achieve a fully conservative, flux-form discretization of linear and nonlinear diffusion equations. A basic consistency and stability analysis is proposed. Numerical examples validate the proposed method and display its potential for consistent semi-Lagrangian discretization of advection diffusion and nonlinear parabolic problems.

  10. FORMED: Bringing Formal Methods to the Engineering Desktop

    Science.gov (United States)

    2016-02-01

    FORMED: BRINGING FORMAL METHODS TO THE ENGINEERING DESKTOP BAE SYSTEMS FEBRUARY 2016 FINAL TECHNICAL REPORT APPROVED FOR PUBLIC RELEASE...This report is published in the interest of scientific and technical information exchange, and its publication does not constitute the Government’s...BRINGING FORMAL METHODS TO THE ENGINEERING DESKTOP 5a. CONTRACT NUMBER FA8750-14-C-0024 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 63781D

  11. Shape measurement system for single point incremental forming (SPIF) manufacts by using trinocular vision and random pattern

    International Nuclear Information System (INIS)

    Setti, Francesco; Bini, Ruggero; Lunardelli, Massimo; Bosetti, Paolo; Bruschi, Stefania; De Cecco, Mariolino

    2012-01-01

    Many contemporary works show the interest of the scientific community in measuring the shape of artefacts made by single point incremental forming. In this paper, we will present an algorithm able to detect feature points with a random pattern, check the compatibility of associations exploiting multi-stereo constraints and reject outliers and perform a 3D reconstruction by dense random patterns. The algorithm is suitable for a real-time application, in fact it needs just three images and a synchronous relatively fast processing. The proposed method has been tested on a simple geometry and results have been compared with a coordinate measurement machine acquisition. (paper)

  12. Forms and Methods of Agricultural Sector Innovative Activity Improvement

    Directory of Open Access Journals (Sweden)

    Aisha S. Ablyaeva

    2013-01-01

    Full Text Available The article is focused on basic forms and methods to improve the efficiency of innovative activity in the agricultural sector of Ukraine. It was determined that the development of agriculture in Ukraine is affected by a number of factors that must be considered to design innovative models of entrepreneurship development and ways to improve the efficiency of innovative entrepreneurship activity.

  13. The Case Method as a Form of Communication.

    Science.gov (United States)

    Kingsley, Lawrence

    1982-01-01

    Questions the wisdom of obscurantism as a basis for case writing. Contends that in its present state the case method, for most students, is an inefficient way of learning. Calls for a consensus that cases should be as well-written as other forms of scholarship. (PD)

  14. Electrodynamics, Differential Forms and the Method of Images

    Science.gov (United States)

    Low, Robert J.

    2011-01-01

    This paper gives a brief description of how Maxwell's equations are expressed in the language of differential forms and use this to provide an elegant demonstration of how the method of images (well known in electrostatics) also works for electrodynamics in the presence of an infinite plane conducting boundary. The paper should be accessible to an…

  15. Delivery Device and Method for Forming the Same

    Science.gov (United States)

    Ma, Peter X. (Inventor); Liu, Xiaohua (Inventor); McCauley, Laurie (Inventor)

    2014-01-01

    A delivery device includes a hollow container, and a plurality of biodegradable and/or erodible polymeric layers established in the container. A layer including a predetermined substance is established between each of the plurality of polymeric layers, whereby degradation of the polymeric layer and release of the predetermined substance occur intermittently. Methods for forming the device are also disclosed herein.

  16. Method of predicting surface deformation in the form of sinkholes

    Energy Technology Data Exchange (ETDEWEB)

    Chudek, M.; Arkuszewski, J.

    1980-06-01

    Proposes a method for predicting probability of sinkhole shaped subsidence, number of funnel-shaped subsidences and size of individual funnels. The following factors which influence the sudden subsidence of the surface in the form of funnels are analyzed: geologic structure of the strata between mining workings and the surface, mining depth, time factor, and geologic disolocations. Sudden surface subsidence is observed only in the case of workings situated up to a few dozen meters from the surface. Using the proposed method is explained with some examples. It is suggested that the method produces correct results which can be used in coal mining and in ore mining. (1 ref.) (In Polish)

  17. Genome sequence of the pattern forming Paenibacillus vortex bacterium reveals potential for thriving in complex environments

    NARCIS (Netherlands)

    Sirota-Madi, A.; Olender, T.; Helman, Y.; Ingham, C.; Brainis, I.; Roth, D.; Hagi, E.; Brodsky, L.; Leshkowitz, D.; Galatenko, V.; Nikolaev, V.; Mugasimangalam, R.C.; Bransburg-Zabary, S.; Gutnick, D.L.; Lancet, D.; Ben-Jacob, E.

    2010-01-01

    Background: The pattern-forming bacterium Paenibacillus vortex is notable for its advanced social behavior, which is reflected in development of colonies with highly intricate architectures. Prior to this study, only two other Paenibacillus species (Paenibacillus sp. JDR-2 and Paenibacillus larvae)

  18. Face recognition system and method using face pattern words and face pattern bytes

    Science.gov (United States)

    Zheng, Yufeng

    2014-12-23

    The present invention provides a novel system and method for identifying individuals and for face recognition utilizing facial features for face identification. The system and method of the invention comprise creating facial features or face patterns called face pattern words and face pattern bytes for face identification. The invention also provides for pattern recognitions for identification other than face recognition. The invention further provides a means for identifying individuals based on visible and/or thermal images of those individuals by utilizing computer software implemented by instructions on a computer or computer system and a computer readable medium containing instructions on a computer system for face recognition and identification.

  19. Bilinear nodal transport method in weighted diamond difference form

    International Nuclear Information System (INIS)

    Azmy, Y.Y.

    1987-01-01

    Nodal methods have been developed and implemented for the numerical solution of the discrete ordinates neutron transport equation. Numerical testing of these methods and comparison of their results to those obtained by conventional methods have established the high accuracy of nodal methods. Furthermore, it has been suggested that the linear-linear approximation is the most computationally efficient, practical nodal approximation. Indeed, this claim has been substantiated by comparing the accuracy in the solution, and the CPU time required to achieve convergence to that solution by several nodal approximations, as well as the diamond difference scheme. Two types of linear-linear nodal methods have been developed in the literature: analytic linear-linear (NLL) methods, in which the transverse-leakage terms are derived analytically, and approximate linear-linear (PLL) methods, in which these terms are approximated. In spite of their higher accuracy, NLL methods result in very complicated discrete-variable equations that exhibit a high degree of coupling, thus requiring special solution algorithms. On the other hand, the sacrificed accuracy in PLL methods is compensated for by the simple discrete-variable equations and diamond-difference-like solution algorithm. In this paper the authors outline the development of an NLL nodal method, the bilinear method, which can be written in a weighted diamond difference form with one spatial weight per dimension that is analytically derived rather than preassigned in an ad hoc fashion

  20. Method for forming H2-permselective oxide membranes

    Science.gov (United States)

    Gavalas, G.R.; Nam, S.W.; Tsapatsis, M.; Kim, S.

    1995-09-26

    Methods are disclosed for forming permselective oxide membranes that are highly selective to permeation of hydrogen by chemical deposition of reactants in the pore of porous tubes, such as Vycor{trademark} glass or Al{sub 2}O{sub 3} tubes. The porous tubes have pores extending through the tube wall. The process involves forming a stream containing a first reactant of the formula RX{sub n}, wherein R is silicon, titanium, boron or aluminum, X is chlorine, bromine or iodine, and n is a number which is equal to the valence of R; and forming another stream containing water vapor as the second reactant. Both of the reactant streams are passed along either the outside or the inside surface of a porous tube and the streams react in the pores of the porous tube to form a nonporous layer of R-oxide in the pores. The membranes are formed by the hydrolysis of the respective halides. In another embodiment, the first reactant stream contains a first reactant having the formula SiH{sub n}Cl{sub 4{minus}n} where n is 1, 2 or 3; and the second reactant stream contains water vapor and oxygen. In still another embodiment the first reactant stream containing a first reactant selected from the group consisting of Cl{sub 3}SiOSiCl{sub 3}, Cl{sub 3}SiOSiCl{sub 2}OSiCl{sub 3}, and mixtures thereof and the second reactant stream contains water vapor. In still another embodiment, membrane formation is carried out by an alternating flow deposition method. This involves a sequence of cycles, each cycle comprising introduction of the halide-containing stream and allowance of a specific time for reaction followed by purge and flow of the water vapor containing stream for a specific length of time. In all embodiments the nonporous layers formed are selectively permeable to hydrogen. 11 figs.

  1. Analysis of Voltage Forming Methods for Multiphase Inverters

    Directory of Open Access Journals (Sweden)

    Tadas Lipinskis

    2013-05-01

    Full Text Available The article discusses advantages of the multiphase AC induction motor over three or less phase motors. It presents possible stator winding configurations for a multiphase induction motor. Various fault control strategies were reviewed for phases feeding the motor. The authors propose a method for quality evaluation of voltage forming algorithm in the inverter. Simulation of a six-phase voltage source inverter, voltage in which is formed using a simple SPWM control algorithm, was performed in Matlab Simulink. Simulation results were evaluated using the proposed method. Inverter’s power stage was powered by 400 V DC source. The spectrum of output currents was analysed and the magnitude of the main frequency component was at least 12 times greater than the next biggest-magnitude component. The value of rectified inverter voltage was 373 V.Article in Lithuanian

  2. Article, component, and method of forming an article

    Science.gov (United States)

    Lacy, Benjamin Paul; Itzel, Gary Michael; Kottilingam, Srikanth Chandrudu; Dutta, Sandip; Schick, David Edward

    2018-05-22

    An article and method of forming an article are provided. The article includes a body portion separating an inner region and an outer region, an aperture in the body portion, the aperture fluidly connecting the inner region to the outer region, and a conduit extending from an outer surface of the body portion at the aperture and being arranged and disposed to controllably direct fluid from the inner region to the outer region. The method includes providing a body portion separating an inner region and an outer region, providing an aperture in the body portion, and forming a conduit over the aperture, the conduit extending from an outer surface of the body portion and being arranged and disposed to controllably direct fluid from the inner region to the outer region. The article is arranged and disposed for insertion within a hot gas path component.

  3. Feeding patterns of molestus and pipiens forms of Culex pipiens (Diptera: Culicidae) in a region of high hybridization.

    Science.gov (United States)

    Gomes, Bruno; Sousa, Carla A; Vicente, José L; Pinho, Leonor; Calderón, Isabel; Arez, Eliane; Almeida, António Pg; Donnelly, Martin J; Pinto, João

    2013-04-11

    Two biological forms of the mosquito Culex pipiens s.s., denoted pipiens and molestus, display behavioural differences that may affect their role as vectors of arboviruses. In this study, the feeding patterns of molestus and pipiens forms were investigated in Comporta (Portugal), where high levels of inter-form admixture have been recorded. Indoor and outdoor mosquito collections were performed in the summer of 2010. Collected Cx. pipiens s.l. females were molecularly identified to species and form by PCR and genotyped for six microsatellites. The source of the blood meal in post-fed females was determined by ELISA and mitochondrial DNA sequencing. The distribution of the forms differed according to the collection method. The molestus form was present only in indoor collections, whereas pipiens and admixed individuals were sampled both indoors and outdoors. In both forms, over 90% of blood meals were made on avian hosts. These included blood meals taken from Passeriformes (Passer domesticus and Turdus merula) by females caught resting inside domestic shelters. Genetic structure and blood meal analyses suggest the presence of a bird biting molestus population in the study area. Both forms were found to rest indoors, mainly in avian shelters, but at least a proportion of females of the pipiens form may bite outdoors in sylvan habitats and then search for anthropogenic resting sites to complete their gonotrophic cycle. This behaviour may potentiate the accidental transmission of arboviruses to humans in the region.

  4. Divergent methylation pattern in adult stage between two forms of Tetranychus urticae (Acari: Tetranychidae).

    Science.gov (United States)

    Yang, Si-Xia; Guo, Chao; Zhao, Xiu-Ting; Sun, Jing-Tao; Hong, Xiao-Yue

    2017-02-19

    The two-spotted spider mite, Tetranychus urticae Koch has two forms: green form and red form. Understanding the molecular basis of how these two forms established without divergent genetic background is an intriguing area. As a well-known epigenetic process, DNA methylation has particularly important roles in gene regulation and developmental variation across diverse organisms that do not alter genetic background. Here, to investigate whether DNA methylation could be associated with different phenotypic consequences in the two forms of T. urticae, we surveyed the genome-wide cytosine methylation status and expression level of DNA methyltransferase 3 (Tudnmt3) throughout their entire life cycle. Methylation-sensitive amplification polymorphism (MSAP) analyses of 585 loci revealed variable methylation patterns in the different developmental stages. In particular, principal coordinates analysis (PCoA) indicates a significant epigenetic differentiation between female adults of the two forms. The gene expression of Tudnmt3 was detected in all examined developmental stages, which was significantly different in the adult stage of the two forms. Together, our results reveal the epigenetic distance between the two forms of T. urticae, suggesting that DNA methylation might be implicated in different developmental demands, and contribute to different phenotypes in the adult stage of these two forms. © 2017 Institute of Zoology, Chinese Academy of Sciences.

  5. A Versatile Method of Patterning Proteins and Cells.

    Science.gov (United States)

    Shrirao, Anil B; Kung, Frank H; Yip, Derek; Firestein, Bonnie L; Cho, Cheul H; Townes-Anderson, Ellen

    2017-02-26

    Substrate and cell patterning techniques are widely used in cell biology to study cell-to-cell and cell-to-substrate interactions. Conventional patterning techniques work well only with simple shapes, small areas and selected bio-materials. This article describes a method to distribute cell suspensions as well as substrate solutions into complex, long, closed (dead-end) polydimethylsiloxane (PDMS) microchannels using negative pressure. This method enables researchers to pattern multiple substrates including fibronectin, collagen, antibodies (Sal-1), poly-D-lysine (PDL), and laminin. Patterning of substrates allows one to indirectly pattern a variety of cells. We have tested C2C12 myoblasts, the PC12 neuronal cell line, embryonic rat cortical neurons, and amphibian retinal neurons. In addition, we demonstrate that this technique can directly pattern fibroblasts in microfluidic channels via brief application of a low vacuum on cell suspensions. The low vacuum does not significantly decrease cell viability as shown by cell viability assays. Modifications are discussed for application of the method to different cell and substrate types. This technique allows researchers to pattern cells and proteins in specific patterns without the need for exotic materials or equipment and can be done in any laboratory with a vacuum.

  6. Effects of cooking methods on electrophoretic patterns of rainbow trout

    Directory of Open Access Journals (Sweden)

    Yasemen Yanar

    2011-07-01

    Full Text Available The aim of this study was to determine the effects of different cooking methods on the electrophoretic patterns of rainbow trout (Oncorhynchus mykiss fillets using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE. Raw rainbow trout were deep-fried, microwaved, grilled, and baked and then monitored for changes in the electrophoretic pattern. All cooking methods resulted in significant moisture loss when compared to the raw sample (P

  7. Basic thinking patterns and working methods for multiple DFX

    DEFF Research Database (Denmark)

    Andreasen, Mogens Myrup; Mortensen, Niels Henrik

    1997-01-01

    This paper attempts to describe the theory and methodologies behind DFX and linking multiple DFX's together. The contribution is an articulation of basic thinking patterns and description of some working methods for handling multiple DFX.......This paper attempts to describe the theory and methodologies behind DFX and linking multiple DFX's together. The contribution is an articulation of basic thinking patterns and description of some working methods for handling multiple DFX....

  8. Methods of forming aluminum oxynitride-comprising bodies, including methods of forming a sheet of transparent armor

    Science.gov (United States)

    Chu, Henry Shiu-Hung [Idaho Falls, ID; Lillo, Thomas Martin [Idaho Falls, ID

    2008-12-02

    The invention includes methods of forming an aluminum oxynitride-comprising body. For example, a mixture is formed which comprises A:B:C in a respective molar ratio in the range of 9:3.6-6.2:0.1-1.1, where "A" is Al.sub.2O.sub.3, "B" is AlN, and "C" is a total of one or more of B.sub.2O.sub.3, SiO.sub.2, Si--Al--O--N, and TiO.sub.2. The mixture is sintered at a temperature of at least 1,600.degree. C. at a pressure of no greater than 500 psia effective to form an aluminum oxynitride-comprising body which is at least internally transparent and has at least 99% maximum theoretical density.

  9. Methods for forming complex oxidation reaction products including superconducting articles

    International Nuclear Information System (INIS)

    Rapp, R.A.; Urquhart, A.W.; Nagelberg, A.S.; Newkirk, M.S.

    1992-01-01

    This patent describes a method for producing a superconducting complex oxidation reaction product of two or more metals in an oxidized state. It comprises positioning at least one parent metal source comprising one of the metals adjacent to a permeable mass comprising at least one metal-containing compound capable of reaction to form the complex oxidation reaction product in step below, the metal component of the at least one metal-containing compound comprising at least a second of the two or more metals, and orienting the parent metal source and the permeable mass relative to each other so that formation of the complex oxidation reaction product will occur in a direction towards and into the permeable mass; and heating the parent metal source in the presence of an oxidant to a temperature region above its melting point to form a body of molten parent metal to permit infiltration and reaction of the molten parent metal into the permeable mass and with the oxidant and the at least one metal-containing compound to form the complex oxidation reaction product, and progressively drawing the molten parent metal source through the complex oxidation reaction product towards the oxidant and towards and into the adjacent permeable mass so that fresh complex oxidation reaction product continues to form within the permeable mass; and recovering the resulting complex oxidation reaction product

  10. Method for forming thermally stable nanoparticles on supports

    Science.gov (United States)

    Roldan Cuenya, Beatriz; Naitabdi, Ahmed R.; Behafarid, Farzad

    2013-08-20

    An inverse micelle-based method for forming nanoparticles on supports includes dissolving a polymeric material in a solvent to provide a micelle solution. A nanoparticle source is dissolved in the micelle solution. A plurality of micelles having a nanoparticle in their core and an outer polymeric coating layer are formed in the micelle solution. The micelles are applied to a support. The polymeric coating layer is then removed from the micelles to expose the nanoparticles. A supported catalyst includes a nanocrystalline powder, thin film, or single crystal support. Metal nanoparticles having a median size from 0.5 nm to 25 nm, a size distribution having a standard deviation .ltoreq.0.1 of their median size are on or embedded in the support. The plurality of metal nanoparticles are dispersed and in a periodic arrangement. The metal nanoparticles maintain their periodic arrangement and size distribution following heat treatments of at least 1,000.degree. C.

  11. Cutting blade dentitions in squaliform sharks form by modification of inherited alternate tooth ordering patterns

    OpenAIRE

    Underwood, Charlie J.; Johanson, Z.; Smith, M.M.

    2016-01-01

    The squaliform sharks represent one of the most speciose shark clades. Many adult squaliforms have blade-like teeth, either on both jaws or restricted to the lower jaw, forming a continuous, serrated blade along the jaw margin. These teeth are replaced as a single unit and successor teeth lack the alternate arrangement present in other elasmobranchs. Micro-CT scans of embryos of squaliforms and a related outgroup (Pristiophoridae) revealed that the squaliform dentition pattern represents a hi...

  12. An experimental design method leading to chemical Turing patterns.

    Science.gov (United States)

    Horváth, Judit; Szalai, István; De Kepper, Patrick

    2009-05-08

    Chemical reaction-diffusion patterns often serve as prototypes for pattern formation in living systems, but only two isothermal single-phase reaction systems have produced sustained stationary reaction-diffusion patterns so far. We designed an experimental method to search for additional systems on the basis of three steps: (i) generate spatial bistability by operating autoactivated reactions in open spatial reactors; (ii) use an independent negative-feedback species to produce spatiotemporal oscillations; and (iii) induce a space-scale separation of the activatory and inhibitory processes with a low-mobility complexing agent. We successfully applied this method to a hydrogen-ion autoactivated reaction, the thiourea-iodate-sulfite (TuIS) reaction, and noticeably produced stationary hexagonal arrays of spots and parallel stripes of pH patterns attributed to a Turing bifurcation. This method could be extended to biochemical reactions.

  13. NNWSI waste form test method for unsaturated disposal conditions

    International Nuclear Information System (INIS)

    Bates, J.K.; Gerding, T.J.

    1985-03-01

    A test method has been developed to measure the release of radionuclides from the waste package under simulated NNWSI repository conditions, and to provide information concerning materials interactions that may occur in the repository. Data are presented from Unsaturated testing of simulated Savannah River Laboratory 165 glass completed through 26 weeks. The relationship between these results and those from parametric and analog testing are described. The data indicate that the waste form test is capable of producing consistent, reproducible results that will be useful in evaluating the role of the waste package in the long-term performance of the repository. 6 refs., 7 figs., 5 tabs

  14. Method of forming capsules containing a precise amount of material

    Science.gov (United States)

    Grossman, M.W.; George, W.A.; Maya, J.

    1986-06-24

    A method of forming a sealed capsule containing a submilligram quantity of mercury or the like, the capsule being constructed from a hollow glass tube, by placing a globule or droplet of the mercury in the tube. The tube is then evacuated and sealed and is subsequently heated so as to vaporize the mercury and fill the tube therewith. The tube is then separated into separate sealed capsules by heating spaced locations along the tube with a coiled heating wire means to cause collapse spaced locations there along and thus enable separation of the tube into said capsules. 7 figs.

  15. Vitality Forms Processing in the Insula during Action Observation: A Multivoxel Pattern Analysis.

    Science.gov (United States)

    Di Cesare, Giuseppe; Valente, Giancarlo; Di Dio, Cinzia; Ruffaldi, Emanuele; Bergamasco, Massimo; Goebel, Rainer; Rizzolatti, Giacomo

    2016-01-01

    Observing the style of an action done by others allows the observer to understand the cognitive state of the agent. This information has been defined by Stern "vitality forms". Previous experiments showed that the dorso-central insula is selectively active both during vitality form observation and execution. In the present study, we presented participants with videos showing hand actions performed with different velocities and asked them to judge either their vitality form (gentle, neutral, rude) or their velocity (slow, medium, fast). The aim of the present study was to assess, using multi-voxel pattern analysis, whether vitality forms and velocities of observed goal-directed actions are differentially processed in the insula, and more specifically whether action velocity is encoded per se or it is an element that triggers neural populations of the insula encoding the vitality form. The results showed that, consistently across subjects, in the dorso-central sector of the insula there were voxels selectively tuned to vitality forms, while voxel tuned to velocity were rare. These results indicate that the dorso-central insula, which previous data showed to be involved in the vitality form processing, contains voxels specific for the action style processing.

  16. Method of forming a ceramic to ceramic joint

    Science.gov (United States)

    Cutler, Raymond Ashton; Hutchings, Kent Neal; Kleinlein, Brian Paul; Carolan, Michael Francis

    2010-04-13

    A method of joining at least two sintered bodies to form a composite structure, includes: providing a joint material between joining surfaces of first and second sintered bodies; applying pressure from 1 kP to less than 5 MPa to provide an assembly; heating the assembly to a conforming temperature sufficient to allow the joint material to conform to the joining surfaces; and further heating the assembly to a joining temperature below a minimum sintering temperature of the first and second sintered bodies. The joint material includes organic component(s) and ceramic particles. The ceramic particles constitute 40-75 vol. % of the joint material, and include at least one element of the first and/or second sintered bodies. Composite structures produced by the method are also disclosed.

  17. Worthwhile optical method for free-form mirrors qualification

    Science.gov (United States)

    Sironi, G.; Canestrari, R.; Toso, G.; Pareschi, G.

    2013-09-01

    We present an optical method for free-form mirrors qualification developed by the Italian National Institute for Astrophysics (INAF) in the context of the ASTRI (Astrofisica con Specchi a Tecnologia Replicante Italiana) Project which includes, among its items, the design, development and installation of a dual-mirror telescope prototype for the Cherenkov Telescope Array (CTA) observatory. The primary mirror panels of the telescope prototype are free-form concave mirrors with few microns accuracy required on the shape error. The developed technique is based on the synergy between a Ronchi-like optical test performed on the reflecting surface and the image, obtained by means of the TraceIT ray-tracing proprietary code, a perfect optics should generate in the same configuration. This deflectometry test allows the reconstruction of the slope error map that the TraceIT code can process to evaluate the measured mirror optical performance at the telescope focus. The advantages of the proposed method is that it substitutes the use of 3D coordinates measuring machine reducing production time and costs and offering the possibility to evaluate on-site the mirror image quality at the focus. In this paper we report the measuring concept and compare the obtained results to the similar ones obtained processing the shape error acquired by means of a 3D coordinates measuring machine.

  18. Frequency guided methods for demodulation of a single fringe pattern.

    Science.gov (United States)

    Wang, Haixia; Kemao, Qian

    2009-08-17

    Phase demodulation from a single fringe pattern is a challenging task but of interest. A frequency-guided regularized phase tracker and a frequency-guided sequential demodulation method with Levenberg-Marquardt optimization are proposed to demodulate a single fringe pattern. Demodulation path guided by the local frequency from the highest to the lowest is applied in both methods. Since critical points have low local frequency values, they are processed last so that the spurious sign problem caused by these points is avoided. These two methods can be considered as alternatives to the effective fringe follower regularized phase tracker. Demodulation results from one computer-simulated and two experimental fringe patterns using the proposed methods will be demonstrated. (c) 2009 Optical Society of America

  19. Investigating Convergence Patterns for Numerical Methods Using Data Analysis

    Science.gov (United States)

    Gordon, Sheldon P.

    2013-01-01

    The article investigates the patterns that arise in the convergence of numerical methods, particularly those in the errors involved in successive iterations, using data analysis and curve fitting methods. In particular, the results obtained are used to convey a deeper level of understanding of the concepts of linear, quadratic, and cubic…

  20. Quantitative EEG Applying the Statistical Recognition Pattern Method

    DEFF Research Database (Denmark)

    Engedal, Knut; Snaedal, Jon; Hoegh, Peter

    2015-01-01

    BACKGROUND/AIM: The aim of this study was to examine the discriminatory power of quantitative EEG (qEEG) applying the statistical pattern recognition (SPR) method to separate Alzheimer's disease (AD) patients from elderly individuals without dementia and from other dementia patients. METHODS...

  1. A new method for discovering behavior patterns among animal movements

    Science.gov (United States)

    Wang, Y.; Luo, Ze; Takekawa, John Y.; Prosser, Diann J.; Xiong, Y.; Newman, S.; Xiao, X.; Batbayar, N.; Spragens, Kyle A.; Balachandran, S.; Yan, B.

    2016-01-01

    Advanced satellite tracking technologies enable biologists to track animal movements at fine spatial and temporal scales. The resultant data present opportunities and challenges for understanding animal behavioral mechanisms. In this paper, we develop a new method to elucidate animal movement patterns from tracking data. Here, we propose the notion of continuous behavior patterns as a concise representation of popular migration routes and underlying sequential behaviors during migration. Each stage in the pattern is characterized in terms of space (i.e., the places traversed during movements) and time (i.e. the time spent in those places); that is, the behavioral state corresponding to a stage is inferred according to the spatiotemporal and sequential context. Hence, the pattern may be interpreted predictably. We develop a candidate generation and refinement framework to derive all continuous behavior patterns from raw trajectories. In the framework, we first define the representative spots to denote the underlying potential behavioral states that are extracted from individual trajectories according to the similarity of relaxed continuous locations in certain distinct time intervals. We determine the common behaviors of multiple individuals according to the spatiotemporal proximity of representative spots and apply a projection-based extension approach to generate candidate sequential behavior sequences as candidate patterns. Finally, the candidate generation procedure is combined with a refinement procedure to derive continuous behavior patterns. We apply an ordered processing strategy to accelerate candidate refinement. The proposed patterns and discovery framework are evaluated through conceptual experiments on both real GPS-tracking and large synthetic datasets.

  2. Vitality Forms Processing in the Insula during Action Observation: A Multivoxel Pattern Analysis

    Science.gov (United States)

    Di Cesare, Giuseppe; Valente, Giancarlo; Di Dio, Cinzia; Ruffaldi, Emanuele; Bergamasco, Massimo; Goebel, Rainer; Rizzolatti, Giacomo

    2016-01-01

    Observing the style of an action done by others allows the observer to understand the cognitive state of the agent. This information has been defined by Stern “vitality forms”. Previous experiments showed that the dorso-central insula is selectively active both during vitality form observation and execution. In the present study, we presented participants with videos showing hand actions performed with different velocities and asked them to judge either their vitality form (gentle, neutral, rude) or their velocity (slow, medium, fast). The aim of the present study was to assess, using multi-voxel pattern analysis, whether vitality forms and velocities of observed goal-directed actions are differentially processed in the insula, and more specifically whether action velocity is encoded per se or it is an element that triggers neural populations of the insula encoding the vitality form. The results showed that, consistently across subjects, in the dorso-central sector of the insula there were voxels selectively tuned to vitality forms, while voxel tuned to velocity were rare. These results indicate that the dorso-central insula, which previous data showed to be involved in the vitality form processing, contains voxels specific for the action style processing. PMID:27375461

  3. The structure environment, rock-magma system, mineral-forming series and pattern of volcanic mineral-forming of uranium deposit in southeast of China

    International Nuclear Information System (INIS)

    Yu Dagan

    1992-01-01

    The Volcanic uranium deposit of rock-magma belt-the Mid-Cz Volcano in the Southeast of China mainly formed around 120 ∼ 130 Ma and 90 ∼ 100 Ma Which is in harmony with the two rock magma activities of k within the region. The rock-magma system of this period formed around the turning period from pressure to tension in the continent margin of southeast China, which is mainly characterized by the appearance of A-type granite and alkaline, sub-alkaline rocks (trachyte, trachyandensite, trachybasalt, basic rock alkaline basalt). The uranium deposit is controlled by the base rift of dissection to the mantle, the volcanic basin is of the double characteristics of transversal rift valley basin (early period) ad tension rift valley basin (laster period). The leading role of the deep source is stressed in terms of internal-forming series of volcanic uranium deposits is considered to exist; and also in terms of internal-forming series of volcanic uranium deposits is considered to exist; and also in terms of mineral-forming patterns, the multi-pattern led by the deep-source is stressed, including the mineral-forming pattern of uranium deposit of continental thermos, repeated periphery mineral-forming pattern of uranium deposit and the mineral-forming pattern of uranium deposit of rising pole-like thermos. Ten suggestions are put forward to the next mineral-search according to the above thoughts

  4. Islamic geometric patterns their historical development and traditional methods of construction

    CERN Document Server

    Bonner, Jay

    2017-01-01

    The main focus of this unique book is an in-depth examination of the polygonal technique; the primary method used by master artists of the past in creating Islamic geometric patterns. The author details the design methodology responsible for this all-but-lost art form and presents evidence for its use from the historical record, both of which are vital contributions to the understanding of this ornamental tradition. Additionally, the author examines the historical development of Islamic geometric patterns, the significance of geometric design within the broader context of Islamic ornament as a whole, the formative role that geometry plays throughout the Islamic ornamental arts (including calligraphy, the floral idiom, dome decoration, geometric patterns, and more), and the underexamined question of pattern classification. Featuring over 600 beautiful color images, Islamic Geometric Patterns: Their Historical Development and Traditional Methods of Construction is a valuable addition to the literature of Islam...

  5. Numerical and Experimental Study on the Formation and Dispersion Patterns of Multiple Explosively Formed Penetrators

    Directory of Open Access Journals (Sweden)

    Jian Feng Liu

    Full Text Available Abstract Three-dimensional numerical simulations and experiments were performed to examine the formation and spatial dispersion patterns of integral multiple explosively formed penetrators (MEFP warhead with seven hemispherical liners. Numerical results had successfully described the formation process and distribution pattern of MEFP. A group of penetrators consisting of a central penetrator surrounded by 6 penetrators is formed during the formation process of MEFP and moves in the direction of aiming position. The maximum divergence angle of the surrounding penetrator group was 7.8°, and the damage area could reach 0.16 m2 at 1.2 m. The laws of perforation dispersion patterns of MEFP were also obtained through a nonlinear fitting of the perforation information on the target at different standoffs. The terminal effects of the MEFP warhead were performed on three #45 steel targets with a dimension of 160cm ( 160cm ( 1.5cm at various standoffs (60, 80, and 120 cm. The simulation results were validated through penetration experiments at different standoffs. It has shown excellent agreement between simulation and experiment results.

  6. Cutting blade dentitions in squaliform sharks form by modification of inherited alternate tooth ordering patterns

    Science.gov (United States)

    Underwood, Charlie; Johanson, Zerina; Smith, Moya Meredith

    2016-11-01

    The squaliform sharks represent one of the most speciose shark clades. Many adult squaliforms have blade-like teeth, either on both jaws or restricted to the lower jaw, forming a continuous, serrated blade along the jaw margin. These teeth are replaced as a single unit and successor teeth lack the alternate arrangement present in other elasmobranchs. Micro-CT scans of embryos of squaliforms and a related outgroup (Pristiophoridae) revealed that the squaliform dentition pattern represents a highly modified version of tooth replacement seen in other clades. Teeth of Squalus embryos are arranged in an alternate pattern, with successive tooth rows containing additional teeth added proximally. Asynchronous timing of tooth production along the jaw and tooth loss prior to birth cause teeth to align in oblique sets containing teeth from subsequent rows; these become parallel to the jaw margin during ontogeny, so that adult Squalus has functional tooth rows comprising obliquely stacked teeth of consecutive developmental rows. In more strongly heterodont squaliforms, initial embryonic lower teeth develop into the oblique functional sets seen in adult Squalus, with no requirement to form, and subsequently lose, teeth arranged in an initial alternate pattern.

  7. Triboelectricity: macroscopic charge patterns formed by self-arraying ions on polymer surfaces.

    Science.gov (United States)

    Burgo, Thiago A L; Ducati, Telma R D; Francisco, Kelly R; Clinckspoor, Karl J; Galembeck, Fernando; Galembeck, Sergio E

    2012-05-15

    Tribocharged polymers display macroscopically patterned positive and negative domains, verifying the fractal geometry of electrostatic mosaics previously detected by electric probe microscopy. Excess charge on contacting polyethylene (PE) and polytetrafluoroethylene (PTFE) follows the triboelectric series but with one caveat: net charge is the arithmetic sum of patterned positive and negative charges, as opposed to the usual assumption of uniform but opposite signal charging on each surface. Extraction with n-hexane preferentially removes positive charges from PTFE, while 1,1-difluoroethane and ethanol largely remove both positive and negative charges. Using suitable analytical techniques (electron energy-loss spectral imaging, infrared microspectrophotometry and carbonization/colorimetry) and theoretical calculations, the positive species were identified as hydrocarbocations and the negative species were identified as fluorocarbanions. A comprehensive model is presented for PTFE tribocharging with PE: mechanochemical chain homolytic rupture is followed by electron transfer from hydrocarbon free radicals to the more electronegative fluorocarbon radicals. Polymer ions self-assemble according to Flory-Huggins theory, thus forming the experimentally observed macroscopic patterns. These results show that tribocharging can only be understood by considering the complex chemical events triggered by mechanical action, coupled to well-established physicochemical concepts. Patterned polymers can be cut and mounted to make macroscopic electrets and multipoles.

  8. Dissipative neurodynamics in perception forms cortical patterns that are stabilized by vortices

    Science.gov (United States)

    Freeman, Walter J.; Vitiello, Giuseppe

    2009-06-01

    In the engagement of the brain with its environment, large-scale neural interactions in brain dynamics create a mesoscopic order parameter, which is evaluated by measuring brain waves (electrocorticogram, ECoG). Such large-scale interactions emerge from the background activity of the brain that is sustained by mutual excitation in cortical populations and manifest in spatiotemporal patterns of neural activity. Band pass filtering reveals beats in ECoG power that recur at theta rates (3-7 Hz) as null spikes in log10 power. The order parameter transiently approaches zero, and the microscopic activity is both disordered and symmetric. As the null spikes terminate, the order parameter resurges and imposes a mesoscopic spatial pattern of ECoG amplitude modulation that then governs the microscopic gamma activity and retrieves the memory of a stimulus. The brain waves reveal a spatial pattern of phase modulation in the form of a cone. The dissipative many-body model of brain dynamics describes these phase cones as vortices, which are initiated by the null spikes, and which stabilize the amplitude modulated patterns embedded in the turbulent neural noise from which they emerge.

  9. Dissipative neurodynamics in perception forms cortical patterns that are stabilized by vortices

    International Nuclear Information System (INIS)

    Freeman, Walter J; Vitiello, Giuseppe

    2009-01-01

    In the engagement of the brain with its environment, large-scale neural interactions in brain dynamics create a mesoscopic order parameter, which is evaluated by measuring brain waves (electrocorticogram, ECoG). Such large-scale interactions emerge from the background activity of the brain that is sustained by mutual excitation in cortical populations and manifest in spatiotemporal patterns of neural activity. Band pass filtering reveals beats in ECoG power that recur at theta rates (3-7 Hz) as null spikes in log 10 power. The order parameter transiently approaches zero, and the microscopic activity is both disordered and symmetric. As the null spikes terminate, the order parameter resurges and imposes a mesoscopic spatial pattern of ECoG amplitude modulation that then governs the microscopic gamma activity and retrieves the memory of a stimulus. The brain waves reveal a spatial pattern of phase modulation in the form of a cone. The dissipative many-body model of brain dynamics describes these phase cones as vortices, which are initiated by the null spikes, and which stabilize the amplitude modulated patterns embedded in the turbulent neural noise from which they emerge.

  10. Comparing urban form correlations of the travel patterns of older and younger adults

    DEFF Research Database (Denmark)

    Meza, Maria Josefina Figueroa; Nielsen, Thomas Alexander Sick; Siren, Anu Kristiina

    2014-01-01

    Using disaggregated data from the Danish National Travel Survey conducted between 2006 - 2011, this study compares the travel patterns of older (65 – 84 years of age) and younger (18 – 64 years of age) adults regarding land use, socio-economic conditions and urban structures. The results highlight...... significant differences between travel patterns and their urban form correlates for the older and younger adult populations. Spatial variables such as density and regional accessibility have different and potentially reverse associations with travel among older adults. The car use of older adults...... is not substituted by other modes in high-density settings, as is the case for younger adults. Older adults do not respond to high regional accessibility by reducing distance traveled, but travel longer and are also more likely to continue using a car in high-access conditions. Spatial structural conditions have...

  11. Combustible structural composites and methods of forming combustible structural composites

    Science.gov (United States)

    Daniels, Michael A.; Heaps, Ronald J.; Steffler, Eric D.; Swank, W. David

    2013-04-02

    Combustible structural composites and methods of forming same are disclosed. In an embodiment, a combustible structural composite includes combustible material comprising a fuel metal and a metal oxide. The fuel metal is present in the combustible material at a weight ratio from 1:9 to 1:1 of the fuel metal to the metal oxide. The fuel metal and the metal oxide are capable of exothermically reacting upon application of energy at or above a threshold value to support self-sustaining combustion of the combustible material within the combustible structural composite. Structural-reinforcing fibers are present in the composite at a weight ratio from 1:20 to 10:1 of the structural-reinforcing fibers to the combustible material. Other embodiments and aspects are disclosed.

  12. Radiation pattern synthesis of planar antennas using the iterative sampling method

    Science.gov (United States)

    Stutzman, W. L.; Coffey, E. L.

    1975-01-01

    A synthesis method is presented for determining an excitation of an arbitrary (but fixed) planar source configuration. The desired radiation pattern is specified over all or part of the visible region. It may have multiple and/or shaped main beams with low sidelobes. The iterative sampling method is used to find an excitation of the source which yields a radiation pattern that approximates the desired pattern to within a specified tolerance. In this paper the method is used to calculate excitations for line sources, linear arrays (equally and unequally spaced), rectangular apertures, rectangular arrays (arbitrary spacing grid), and circular apertures. Examples using these sources to form patterns with shaped main beams, multiple main beams, shaped sidelobe levels, and combinations thereof are given.

  13. Comparative phylogeography: concepts, methods and general patterns in neotropical birds

    International Nuclear Information System (INIS)

    Arbelaez Cortes, Enrique

    2012-01-01

    Understanding the patterns and processes involved in intraspecific lineages diversification in time and space is the aim of phylogeography. The comparison of those phylogeographic patterns among co-distributed species shows insights of a community history. Here I review the concepts and methodologies of comparative phylogeography, an active research field that has heterogeneous analytical methods. In order to present a framework for phylogeography in the neotropics, I comment the general phylogeographic patterns of the birds from this region. this review is based on more than 100 studies conducted during the last 25 years and indicate that despite different co-distributed species seem to share some points in their phylogeographic pattern they have idiosyncratic aspects, indicating an unique history for each one.

  14. Synthesis of freeform refractive surfaces forming various radiation patterns using interpolation

    Science.gov (United States)

    Voznesenskaya, Anna; Mazur, Iana; Krizskiy, Pavel

    2017-09-01

    Optical freeform surfaces are very popular today in such fields as lighting systems, sensors, photovoltaic concentrators, and others. The application of such surfaces allows to obtain systems with a new quality with a reduced number of optical components to ensure high consumer characteristics: small size, weight, high optical transmittance. This article presents the methods of synthesis of refractive surface for a given source and the radiation pattern of various shapes using a computer simulation cubic spline interpolation.

  15. A simple identification method for spore-forming bacteria showing high resistance against γ-rays

    International Nuclear Information System (INIS)

    Koshikawa, Tomihiko; Sone, Koji; Kobayashi, Toshikazu

    1993-01-01

    A simple identification method was developed for spore-forming bacteria which are highly resistant against γ-rays. Among 23 species of Bacillus studied, the spores of Bacillus megaterium, B. cereus, B. thuringiensis, B. pumilus and B. aneurinolyticus showed high resistance against γ-rays as compared with other spores of Bacillus species. Combination of the seven kinds of biochemical tests, namely, the citrate utilization test, nitrate reduction test, starch hydrolysis test, Voges-Proskauer reaction test, gelatine hydrolysis test, mannitol utilization test and xylose utilization test showed a characteristic pattern for each species of Bacillus. The combination pattern of each the above tests with a few supplementary test, if necessary, was useful to identify Bacillus species showing high radiation resistance against γ-rays. The method is specific for B. megaterium, B. thuringiensis and B. pumilus, and highly selective for B. aneurinolyticus and B. cereus. (author)

  16. A Pattern-Oriented Approach to a Methodical Evaluation of Modeling Methods

    Directory of Open Access Journals (Sweden)

    Michael Amberg

    1996-11-01

    Full Text Available The paper describes a pattern-oriented approach to evaluate modeling methods and to compare various methods with each other from a methodical viewpoint. A specific set of principles (the patterns is defined by investigating the notations and the documentation of comparable modeling methods. Each principle helps to examine some parts of the methods from a specific point of view. All principles together lead to an overall picture of the method under examination. First the core ("method neutral" meaning of each principle is described. Then the methods are examined regarding the principle. Afterwards the method specific interpretations are compared with each other and with the core meaning of the principle. By this procedure, the strengths and weaknesses of modeling methods regarding methodical aspects are identified. The principles are described uniformly using a principle description template according to descriptions of object oriented design patterns. The approach is demonstrated by evaluating a business process modeling method.

  17. Subspace methods for pattern recognition in intelligent environment

    CERN Document Server

    Jain, Lakhmi

    2014-01-01

    This research book provides a comprehensive overview of the state-of-the-art subspace learning methods for pattern recognition in intelligent environment. With the fast development of internet and computer technologies, the amount of available data is rapidly increasing in our daily life. How to extract core information or useful features is an important issue. Subspace methods are widely used for dimension reduction and feature extraction in pattern recognition. They transform a high-dimensional data to a lower-dimensional space (subspace), where most information is retained. The book covers a broad spectrum of subspace methods including linear, nonlinear and multilinear subspace learning methods and applications. The applications include face alignment, face recognition, medical image analysis, remote sensing image classification, traffic sign recognition, image clustering, super resolution, edge detection, multi-view facial image synthesis.

  18. Pattern of Family Planning Methods used by Antenatal Patients in ...

    African Journals Online (AJOL)

    This study aimed at assessing the pattern of family planning methods used by antenatal patients at Federal Medical Centre, Owo, Ondo State, Nigeria. The study was conducted between December,2007 and February,2008 at the antenatal clinic of the hospital. Ethical clearance was obtained from the Ethical committee of ...

  19. Assessment methods of injection moulded nano-patterned surfaces

    DEFF Research Database (Denmark)

    Menotti, S.; Bisacco, G.; Hansen, H. N.

    2014-01-01

    algorithm for feature recognition. To compare the methods, the mould insert and a number of replicated nano-patterned surfaces, injection moulded with an induction heating aid, were measured on nominally identical locations by means of an atomic force microscope mounted on a manual CMM....

  20. Ophthalmic Drug Dosage Forms: Characterisation and Research Methods

    OpenAIRE

    Baranowski, Przemysław; Karolewicz, Bożena; Gajda, Maciej; Pluta, Janusz

    2014-01-01

    This paper describes hitherto developed drug forms for topical ocular administration, that is, eye drops, ointments, in situ gels, inserts, multicompartment drug delivery systems, and ophthalmic drug forms with bioadhesive properties. Heretofore, many studies have demonstrated that new and more complex ophthalmic drug forms exhibit advantage over traditional ones and are able to increase the bioavailability of the active substance by, among others, reducing the susceptibility of drug forms to...

  1. Method of forming composite fiber blends and molding same

    Science.gov (United States)

    McMahon, Paul E. (Inventor); Chung, Tai-Shung (Inventor)

    1989-01-01

    The instant invention involves a process used in preparing fibrous tows which may be formed into polymeric plastic composites. The process involves the steps of (a) forming a tow of strong filamentary materials; (b) forming a thermoplastic polymeric fiber; (c) intermixing the two tows; and (d) withdrawing the intermixed tow for further use.

  2. Pattern recognition as a method of data analysis

    Energy Technology Data Exchange (ETDEWEB)

    Caputo, M.

    1978-11-15

    The method of pattern recognition has been used in biological and social sciences and has been recently introduced for the solution of geological and geophysical problems such as oil and ore prospecting and seismological prediction. The method is briefly illustrated by an application to earthquake prediction in Italy in which topographic and geologic maps are used in conjunction with earthquake catalogs. 3 figures, 1 table.

  3. Geometric Methods in the Algebraic Theory of Quadratic Forms : Summer School

    CERN Document Server

    2004-01-01

    The geometric approach to the algebraic theory of quadratic forms is the study of projective quadrics over arbitrary fields. Function fields of quadrics have been central to the proofs of fundamental results since the renewal of the theory by Pfister in the 1960's. Recently, more refined geometric tools have been brought to bear on this topic, such as Chow groups and motives, and have produced remarkable advances on a number of outstanding problems. Several aspects of these new methods are addressed in this volume, which includes - an introduction to motives of quadrics by Alexander Vishik, with various applications, notably to the splitting patterns of quadratic forms under base field extensions; - papers by Oleg Izhboldin and Nikita Karpenko on Chow groups of quadrics and their stable birational equivalence, with application to the construction of fields which carry anisotropic quadratic forms of dimension 9, but none of higher dimension; - a contribution in French by Bruno Kahn which lays out a general fra...

  4. Method of forming buried oxide layers in silicon

    Science.gov (United States)

    Sadana, Devendra Kumar; Holland, Orin Wayne

    2000-01-01

    A process for forming Silicon-On-Insulator is described incorporating the steps of ion implantation of oxygen into a silicon substrate at elevated temperature, ion implanting oxygen at a temperature below 200.degree. C. at a lower dose to form an amorphous silicon layer, and annealing steps to form a mixture of defective single crystal silicon and polycrystalline silicon or polycrystalline silicon alone and then silicon oxide from the amorphous silicon layer to form a continuous silicon oxide layer below the surface of the silicon substrate to provide an isolated superficial layer of silicon. The invention overcomes the problem of buried isolated islands of silicon oxide forming a discontinuous buried oxide layer.

  5. Forming MOFs into spheres by use of molecular gastronomy methods.

    Science.gov (United States)

    Spjelkavik, Aud I; Aarti; Divekar, Swapnil; Didriksen, Terje; Blom, Richard

    2014-07-14

    A novel method utilizing hydrocolloids to prepare nicely shaped spheres of metal-organic frameworks (MOFs) has been developed. Microcrystalline CPO-27-Ni particles are dispersed in either alginate or chitosan solutions, which are added dropwise to solutions containing, respectively, either divalent group 2 cations or base that act as gelling agents. Well-shaped spheres are immediately formed, which can be dried into spheres containing mainly MOF (>95 wt %). The spheronizing procedures have been optimized with respect to maximum specific surface area, shape, and particle density of the final sphere. At optimal conditions, well-shaped 2.5-3.5 mm diameter CPO-27-Ni spheres with weight-specific surface areas <10 % lower than the nonformulated CPO-27-Ni precursor, and having sphere densities in the range 0.8 to 0.9 g cm(-3) and particle crushing strengths above 20 N, can be obtained. The spheres are well suited for use in fixed-bed catalytic or adsorption processes. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Decoupled Simulation Method For Incremental Sheet Metal Forming

    International Nuclear Information System (INIS)

    Sebastiani, G.; Brosius, A.; Tekkaya, A. E.; Homberg, W.; Kleiner, M.

    2007-01-01

    Within the scope of this article a decoupling algorithm to reduce computing time in Finite Element Analyses of incremental forming processes will be investigated. Based on the given position of the small forming zone, the presented algorithm aims at separating a Finite Element Model in an elastic and an elasto-plastic deformation zone. Including the elastic response of the structure by means of model simplifications, the costly iteration in the elasto-plastic zone can be restricted to the small forming zone and to few supporting elements in order to reduce computation time. Since the forming zone moves along the specimen, an update of both, forming zone with elastic boundary and supporting structure, is needed after several increments.The presented paper discusses the algorithmic implementation of the approach and introduces several strategies to implement the denoted elastic boundary condition at the boundary of the plastic forming zone

  7. Ophthalmic Drug Dosage Forms: Characterisation and Research Methods

    Directory of Open Access Journals (Sweden)

    Przemysław Baranowski

    2014-01-01

    Full Text Available This paper describes hitherto developed drug forms for topical ocular administration, that is, eye drops, ointments, in situ gels, inserts, multicompartment drug delivery systems, and ophthalmic drug forms with bioadhesive properties. Heretofore, many studies have demonstrated that new and more complex ophthalmic drug forms exhibit advantage over traditional ones and are able to increase the bioavailability of the active substance by, among others, reducing the susceptibility of drug forms to defense mechanisms of the human eye, extending contact time of drug with the cornea, increasing the penetration through the complex anatomical structure of the eye, and providing controlled release of drugs into the eye tissues, which allows reducing the drug application frequency. The rest of the paper describes recommended in vitro and in vivo studies to be performed for various ophthalmic drugs forms in order to assess whether the form is acceptable from the perspective of desired properties and patient’s compliance.

  8. A method and machine for forming pleated and bellow tubes

    International Nuclear Information System (INIS)

    Banks, J.W.

    1975-01-01

    In a machine, the rollers outside the rough tube are rigidly supported for assuring the accurate forming of each turn of the pleated tube, the latter being position-indexed independently of the already formed turns. An inner roller is supported by a device for adjusting and indexing the position thereof on a carriage. The thus obtained tubes are suitable, in particular, for forming expansion sealing joints for power generators or nuclear reactors [fr

  9. Simple statistical methods for software engineering data and patterns

    CERN Document Server

    Pandian, C Ravindranath

    2015-01-01

    Although there are countless books on statistics, few are dedicated to the application of statistical methods to software engineering. Simple Statistical Methods for Software Engineering: Data and Patterns fills that void. Instead of delving into overly complex statistics, the book details simpler solutions that are just as effective and connect with the intuition of problem solvers.Sharing valuable insights into software engineering problems and solutions, the book not only explains the required statistical methods, but also provides many examples, review questions, and case studies that prov

  10. Trade unions and social movements: methods and forms of interaction

    Directory of Open Access Journals (Sweden)

    O. L. Tupytsia

    2017-07-01

    New typological features of social movements are formed on the basis of a new type of social and communication links. Social hierarchy and class antagonisms, which provided the basis for the existence and development of trade unions in the past, expired. Therefore, the organizational forms of trade unions as social movements have become more available and acceptable for contemporary citizens.

  11. Life-forms and seasonal patterns in the pteridophytes in Zambia

    Directory of Open Access Journals (Sweden)

    Jan Kornaś

    2015-01-01

    Full Text Available 146 species of pteridophytes occurring in Zambia were classified into Raunkiaer's life-form classes. The hemicryptophytes are dominant and include the most widely distributed species. The phanerophytes (tree-ferns and lianas and the epiphytes are rather scarce and limited to or concentrated in the higher-rainfall areas in the northern part of the country. Simplified diagrams of periodicity were constructed for all Zambian pteridophyte species. Three major types of seasonal pattern of growth and dormancy were distinguished: the evergreen type, the poikilohydrous type, and the "summer-green" type. The first of them is connected with the local conditions of continuously wet non-zonal sites, while the two others clearly reflect the peculiarities of the zonal climate of Zambia.

  12. A Bayesian statistical method for quantifying model form uncertainty and two model combination methods

    International Nuclear Information System (INIS)

    Park, Inseok; Grandhi, Ramana V.

    2014-01-01

    Apart from parametric uncertainty, model form uncertainty as well as prediction error may be involved in the analysis of engineering system. Model form uncertainty, inherently existing in selecting the best approximation from a model set cannot be ignored, especially when the predictions by competing models show significant differences. In this research, a methodology based on maximum likelihood estimation is presented to quantify model form uncertainty using the measured differences of experimental and model outcomes, and is compared with a fully Bayesian estimation to demonstrate its effectiveness. While a method called the adjustment factor approach is utilized to propagate model form uncertainty alone into the prediction of a system response, a method called model averaging is utilized to incorporate both model form uncertainty and prediction error into it. A numerical problem of concrete creep is used to demonstrate the processes for quantifying model form uncertainty and implementing the adjustment factor approach and model averaging. Finally, the presented methodology is applied to characterize the engineering benefits of a laser peening process

  13. Space discretization in SN methods: Features, improvements and convergence patterns

    International Nuclear Information System (INIS)

    Coppa, G.G.M.; Lapenta, G.; Ravetto, P.

    1990-01-01

    A comparative analysis of the space discretization schemes currently used in S N methods is performed and special attention is devoted to direct integration techniques. Some improvements are proposed in one- and two-dimensional applications, which are based on suitable choices for the spatial variation of the collision source. A study of the convergence pattern is carried out for eigenvalue calculations within the space asymptotic approximation by means of both analytical and numerical investigations. (orig.) [de

  14. Neurocomputing methods for pattern recognition in nuclear physics

    Energy Technology Data Exchange (ETDEWEB)

    Gyulassy, M.; Dong, D.; Harlander, M. [Lawrence Berkeley Lab., CA (United States)

    1991-12-31

    We review recent progress on the development and applications of novel neurocomputing techniques for pattern recognition problems of relevance to RHIC experiments. The Elastic Tracking algorithm is shown to achieve sub-pad two track resolution without preprocessing. A high pass neural filter is developed for jet analysis and singular deconvolution methods are shown to recover the primordial jet distribution to a surprising high degree of accuracy.

  15. Method to manufacture bit patterned magnetic recording media

    Science.gov (United States)

    Raeymaekers, Bart; Sinha, Dipen N

    2014-05-13

    A method to increase the storage density on magnetic recording media by physically separating the individual bits from each other with a non-magnetic medium (so-called bit patterned media). This allows the bits to be closely packed together without creating magnetic "cross-talk" between adjacent bits. In one embodiment, ferromagnetic particles are submerged in a resin solution, contained in a reservoir. The bottom of the reservoir is made of piezoelectric material.

  16. Method for depleting BWRs using optimal control rod patterns

    International Nuclear Information System (INIS)

    Taner, M.S.; Levine, S.H.; Hsiao, M.Y.

    1991-01-01

    Control rod (CR) programming is an essential core management activity for boiling water reactors (BWRs). After establishing a core reload design for a BWR, CR programming is performed to develop a sequence of exposure-dependent CR patterns that assure the safe and effective depletion of the core through a reactor cycle. A time-variant target power distribution approach has been assumed in this study. The authors have developed OCTOPUS to implement a new two-step method for designing semioptimal CR programs for BWRs. The optimization procedure of OCTOPUS is based on the method of approximation programming and uses the SIMULATE-E code for nucleonics calculations

  17. A System of Test Methods for Sheet Metal Forming Tribology

    DEFF Research Database (Denmark)

    Bay, Niels; Olsson, David Dam; Andreasen, Jan Lasson

    2007-01-01

    Sheet metal forming of tribologically difficult materials such as stainless steel, Al-alloys and Ti-alloys or forming in tribologically difficult operations like ironing, punching or deep drawing of thick plate requires often use of environmentally hazardous lubricants such as chlorinated paraffin...... oils in order to avoid galling. The present paper describes a systematic research in the development of new, environmentally harmless lubricants focusing on the lubricant testing aspects. A system of laboratory tests has been developed to study the lubricant performance under the very varied conditions...... appearing in different sheet forming operations such as stamping, deep drawing, ironing and punching. The laboratory tests have been especially designed to model the conditions in industrial production....

  18. Friction stir method for forming structures and materials

    Science.gov (United States)

    Feng, Zhili; David, Stan A.; Frederick, David Alan

    2011-11-22

    Processes for forming an enhanced material or structure are disclosed. The structure typically includes a preform that has a first common surface and a recess below the first common surface. A filler is added to the recess and seams are friction stir welded, and materials may be stir mixed.

  19. Methods of Forming Professional Competence of Students as Future Teachers

    Science.gov (United States)

    Omarov, Yessen B.; Toktarbayev, Darkhan Gabdyl-Samatovich; Rybin, Igor Vyacheslavovich; Saliyevaa, Aigul Zhanayevna; Zhumabekova, Fatima Niyazbekovna; Hamzina, Sholpan; Baitlessova, Nursulu; Sakenov, Janat

    2016-01-01

    The article presents an analysis of the problem of professional competence; a methodological basis of forming professional competence of college students as future teachers is established. The essence of professional competence is defined. The structure has been experimentally proved and developed; the contents, criteria and levels of professional…

  20. Method for forming microspheres for encapsulation of nuclear waste

    Science.gov (United States)

    Angelini, Peter; Caputo, Anthony J.; Hutchens, Richard E.; Lackey, Walter J.; Stinton, David P.

    1984-01-01

    Microspheres for nuclear waste storage are formed by gelling droplets containing the waste in a gelation fluid, transferring the gelled droplets to a furnace without the washing step previously used, and heating the unwashed gelled droplets in the furnace under temperature or humidity conditions that result in a substantially linear rate of removal of volatile components therefrom.

  1. Method of inactivating reproducible forms of mycoplasma in biological preparations

    International Nuclear Information System (INIS)

    Veber, P.; Jurmanova, K.; Lesko, J.; Hana, L.; Veber, V.

    1978-01-01

    Inactivation of mycoplasms in biological materials was achieved using gamma radiation with a dose rate of 1x10 4 to 5x10 6 rads/h for 1 to 250 hours. The technique is advantageous for allowing the inactivation of the final form of products (tablets, vaccines, etc.). (J.P.)

  2. Wafer-Level Packaging Method for RF MEMS Applications Using Pre-Patterned BCB Polymer

    OpenAIRE

    Zhuhao Gong; Yulong Zhang; Xin Guo; Zewen Liu

    2018-01-01

    A radio-frequency micro-electro-mechanical system (RF MEMS) wafer-level packaging (WLP) method using pre-patterned benzo-cyclo-butene (BCB) polymers with a high-resistivity silicon cap is proposed to achieve high bonding quality and excellent RF performance. In this process, the BCB polymer was pre-defined to form the sealing ring and bonding layer by the spin-coating and patterning of photosensitive BCB before the cavity formation. During anisotropic wet etching of the silicon wafer to gener...

  3. Methods, forms and means of forming the religious literacy among the students

    Directory of Open Access Journals (Sweden)

    Efimov Vladimir Fedorovich

    2016-12-01

    Full Text Available The article discusses the range of problems related to the formation of religious literacy among the students. The author specifically notes that this aspect is formed in an ideological key and includes understanding of the nature and typology of religions, their historical origins and current status, and the presence of tolerance towards persons with different beliefs, and ability to fruitful (without violence to conscience someone coexistence and social interaction. To achieve this purpose the article presents and uses the described methodological tools.

  4. Elevational plant species richness patterns and their drivers across non-endemics, endemics and growth forms in the Eastern Himalaya.

    Science.gov (United States)

    Manish, Kumar; Pandit, Maharaj K; Telwala, Yasmeen; Nautiyal, Dinesh C; Koh, Lian Pin; Tiwari, Sudha

    2017-09-01

    Despite decades of research, ecologists continue to debate how spatial patterns of species richness arise across elevational gradients on the Earth. The equivocal results of these studies could emanate from variations in study design, sampling effort and data analysis. In this study, we demonstrate that the richness patterns of 2,781 (2,197 non-endemic and 584 endemic) angiosperm species along an elevational gradient of 300-5,300 m in the Eastern Himalaya are hump-shaped, spatial scale of extent (the proportion of elevational gradient studied) dependent and growth form specific. Endemics peaked at higher elevations than non-endemics across all growth forms (trees, shrubs, climbers, and herbs). Richness patterns were influenced by the proportional representation of the largest physiognomic group (herbs). We show that with increasing spatial scale of extent, the richness patterns change from a monotonic to a hump-shaped pattern and richness maxima shift toward higher elevations across all growth forms. Our investigations revealed that the combination of ambient energy (air temperature, solar radiation, and potential evapo-transpiration) and water availability (soil water content and precipitation) were the main drivers of elevational plant species richness patterns in the Himalaya. This study highlights the importance of factoring in endemism, growth forms, and spatial scale when investigating elevational gradients of plant species distributions and advances our understanding of how macroecological patterns arise.

  5. Solare Cell Roof Tile And Method Of Forming Same

    Science.gov (United States)

    Hanoka, Jack I.; Real, Markus

    1999-11-16

    A solar cell roof tile includes a front support layer, a transparent encapsulant layer, a plurality of interconnected solar cells and a backskin layer. The front support layer is formed of light transmitting material and has first and second surfaces. The transparent encapsulant layer is disposed adjacent the second surface of the front support layer. The interconnected solar cells has a first surface disposed adjacent the transparent encapsulant layer. The backskin layer has a first surface disposed adjacent a second surface of the interconnected solar cells, wherein a portion of the backskin layer wraps around and contacts the first surface of the front support layer to form the border region. A portion of the border region has an extended width. The solar cell roof tile may have stand-offs disposed on the extended width border region for providing vertical spacing with respect to an adjacent solar cell roof tile.

  6. Numerical Methods for Plate Forming by Line Heating

    DEFF Research Database (Denmark)

    Clausen, Henrik Bisgaard

    2000-01-01

    Few researchers have addressed so far the topic Line Heating in the search for better control of the process. Various methods to help understanding the mechanics have been used, including beam analysis approximation, equivalent force calculation and three-dimensional finite element analysis. I...... consider here finite element methods to model the behaviour and to predict the heating paths....

  7. Pattern recognition in complex activity travel patterns : comparison of Euclidean distance, signal-processing theoretical, and multidimensional sequence alignment methods

    NARCIS (Netherlands)

    Joh, C.H.; Arentze, T.A.; Timmermans, H.J.P.

    2001-01-01

    The application of a multidimensional sequence alignment method for classifying activity travel patterns is reported. The method was developed as an alternative to the existing classification methods suggested in the transportation literature. The relevance of the multidimensional sequence alignment

  8. Method of forming catalyst layer by single step infiltration

    Science.gov (United States)

    Gerdes, Kirk; Lee, Shiwoo; Dowd, Regis

    2018-05-01

    Provided herein is a method for electrocatalyst infiltration of a porous substrate, of particular use for preparation of a cathode for a solid oxide fuel cell. The method generally comprises preparing an electrocatalyst infiltrate solution comprising an electrocatalyst, surfactant, chelating agent, and a solvent; pretreating a porous mixed ionic-electric conductive substrate; and applying the electrocatalyst infiltration solution to the porous mixed ionic-electric conductive substrate.

  9. Method of forming an electrically conductive cellulose composite

    Science.gov (United States)

    Evans, Barbara R [Oak Ridge, TN; O'Neill, Hugh M [Knoxville, TN; Woodward, Jonathan [Ashtead, GB

    2011-11-22

    An electrically conductive cellulose composite includes a cellulose matrix and an electrically conductive carbonaceous material incorporated into the cellulose matrix. The electrical conductivity of the cellulose composite is at least 10 .mu.S/cm at 25.degree. C. The composite can be made by incorporating the electrically conductive carbonaceous material into a culture medium with a cellulose-producing organism, such as Gluconoacetobacter hansenii. The composites can be used to form electrodes, such as for use in membrane electrode assemblies for fuel cells.

  10. Dual phase magnetic material component and method of forming

    Science.gov (United States)

    Dial, Laura Cerully; DiDomizio, Richard; Johnson, Francis

    2017-04-25

    A magnetic component having intermixed first and second regions, and a method of preparing that magnetic component are disclosed. The first region includes a magnetic phase and the second region includes a non-magnetic phase. The method includes mechanically masking pre-selected sections of a surface portion of the component by using a nitrogen stop-off material and heat-treating the component in a nitrogen-rich atmosphere at a temperature greater than about 900.degree. C. Both the first and second regions are substantially free of carbon, or contain only limited amounts of carbon; and the second region includes greater than about 0.1 weight % of nitrogen.

  11. Form of silicon and method of making the same

    Science.gov (United States)

    Strobel, Timothy A.; Kim, Duck Young; Kurakevych, Oleksandr O.

    2017-07-04

    The invention relates to a new phase of silicon, Si.sub.24, and a method of making the same. Si.sub.24 has a quasi-direct band gap, with a direct gap value of 1.34 eV and an indirect gap value of 1.3 eV. The invention also relates to a compound of the formula Na.sub.4Si.sub.24 and a method of making the same. N.sub.a4Si.sub.24 may be used as a precursor to make Si.sub.24.

  12. Recursive form of general limited memory variable metric methods

    Czech Academy of Sciences Publication Activity Database

    Lukšan, Ladislav; Vlček, Jan

    2013-01-01

    Roč. 49, č. 2 (2013), s. 224-235 ISSN 0023-5954 Institutional support: RVO:67985807 Keywords : unconstrained optimization * large scale optimization * limited memory methods * variable metric updates * recursive matrix formulation * algorithms Subject RIV: BA - General Mathematics Impact factor: 0.563, year: 2013 http://dml.cz/handle/10338.dmlcz/143365

  13. Method of making nanostructured glass-ceramic waste forms

    Science.gov (United States)

    Gao, Huizhen; Wang, Yifeng; Rodriguez, Mark A.; Bencoe, Denise N.

    2012-12-18

    A method of rendering hazardous materials less dangerous comprising trapping the hazardous material in nanopores of a nanoporous composite material, reacting the trapped hazardous material to render it less volatile/soluble, sealing the trapped hazardous material, and vitrifying the nanoporous material containing the less volatile/soluble hazardous material.

  14. Developing feasible loading patterns using perturbation theory methods

    International Nuclear Information System (INIS)

    White, J.R.; Avila, K.M.

    1990-01-01

    This work illustrates an approach to core reload design that combines the power of integer programming with the efficiency of generalized perturbation theory. The main use of the method is as a tool to help the design engineer identify feasible loading patterns with minimum time and effort. The technique is highly successful for the burnable poison (BP) loading problem, but the unpredictable behavior of the branch-and-bound algorithm degrades overall performance for large problems. Unfortunately, the combined fuel shuffling plus BP optimization problem falls into this latter classification. Overall, however, the method shows great promise for significantly reducing the manpower time required for the reload design process. And it may even give the further benefit of better designs and improved performance

  15. Micro-and/or nano-scale patterned porous membranes, methods of making membranes, and methods of using membranes

    KAUST Repository

    Wang, Xianbin; Chen, Wei; Wang, Zhihong; Zhang, Xixiang; Yue, Weisheng; Lai, Zhiping

    2015-01-01

    Embodiments of the present disclosure provide for materials that include a pre-designed patterned, porous membrane (e.g., micro- and/or nano-scale patterned), structures or devices that include a pre-designed patterned, porous membrane, methods of making pre-designed patterned, porous membranes, methods of separation, and the like.

  16. Micro-and/or nano-scale patterned porous membranes, methods of making membranes, and methods of using membranes

    KAUST Repository

    Wang, Xianbin

    2015-01-22

    Embodiments of the present disclosure provide for materials that include a pre-designed patterned, porous membrane (e.g., micro- and/or nano-scale patterned), structures or devices that include a pre-designed patterned, porous membrane, methods of making pre-designed patterned, porous membranes, methods of separation, and the like.

  17. Effect of long-term irrigation patterns on phosphorus forms and distribution in the brown soil zone.

    Directory of Open Access Journals (Sweden)

    Chang Liu

    Full Text Available Continuous application of P fertilizers under different irrigation patterns can change soil phosphorus (P chemical behavior and increase soil P levels that are of environmental concern. To assess the effect of long-term different irrigation patterns on soil P fractions and availability, this study examined sequential changes in soil organic P and inorganic P from furrow irrigation (FI, surface drip irrigation (SUR, and subsurface drip irrigation (SDI in the brown soil zone (0-60 cm during 1998 to 2011. Analyses of soil P behavior showed that the levels of total P are frequently high on top soil layers. The total P (TP contents of the entire soil profiles under three irrigation treatments were 830.2-3180.1 mg/kg. The contents of available P (AP were 72.6-319.3 mg P/kg soil through soil profiles. The greatest TP and AP contents were obtained within the upper soil layers in FI. Results of Hedley's P fractionation indicate that HCl-P is a dominant form and the proportion to TP ranges from 29% to 43% in all three methods. The contents of various fractions of P were positively correlated with the levels of total carbon (TC, total inorganic carbon (TIC, and calcium (Ca, whereas the P fractions had negative correlation with pH in all soil samples. Regression models proved that NaHCO3-Po was an important factor in determining the amount of AP in FI. H2O-Po, NaHCO3-Po, and NaOH-Pi were related to available P values in SUR. NaHCO3-Po and NaOH-Po played important roles in SDI. The tomato yield under SUR was higher than SDI and FI. The difference of P availability was also controlled by the physicochemical soil properties under different irrigation schedule. SUR was a reasonable irrigation pattern to improve the utilization efficiency of water and fertilizer.

  18. Manganite perovskite ceramics, their precursors and methods for forming

    Science.gov (United States)

    Payne, David Alan; Clothier, Brent Allen

    2015-03-10

    Disclosed are a variety of ceramics having the formula Ln.sub.1-xM.sub.xMnO.sub.3, where 0.Itoreq.x.Itoreq.1 and where Ln is La, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu or Y; M is Ca, Sr, Ba, Cd, or Pb; manganite precursors for preparing the ceramics; a method for preparing the precursors; and a method for transforming the precursors into uniform, defect-free ceramics having magnetoresistance properties. The manganite precursors contain a sol and are derived from the metal alkoxides: Ln(OR).sub.3, M(OR).sub.2 and Mn(OR).sub.2, where R is C.sub.2 to C.sub.6 alkyl or C.sub.3 to C.sub.9 alkoxyalkyl, or C.sub.6 to C.sub.9 aryl. The preferred ceramics are films prepared by a spin coating method and are particularly suited for incorporation into a device such as an integrated circuit device.

  19. Sequential optimization and reliability assessment method for metal forming processes

    International Nuclear Information System (INIS)

    Sahai, Atul; Schramm, Uwe; Buranathiti, Thaweepat; Chen Wei; Cao Jian; Xia, Cedric Z.

    2004-01-01

    Uncertainty is inevitable in any design process. The uncertainty could be due to the variations in geometry of the part, material properties or due to the lack of knowledge about the phenomena being modeled itself. Deterministic design optimization does not take uncertainty into account and worst case scenario assumptions lead to vastly over conservative design. Probabilistic design, such as reliability-based design and robust design, offers tools for making robust and reliable decisions under the presence of uncertainty in the design process. Probabilistic design optimization often involves double-loop procedure for optimization and iterative probabilistic assessment. This results in high computational demand. The high computational demand can be reduced by replacing computationally intensive simulation models with less costly surrogate models and by employing Sequential Optimization and reliability assessment (SORA) method. The SORA method uses a single-loop strategy with a series of cycles of deterministic optimization and reliability assessment. The deterministic optimization and reliability assessment is decoupled in each cycle. This leads to quick improvement of design from one cycle to other and increase in computational efficiency. This paper demonstrates the effectiveness of Sequential Optimization and Reliability Assessment (SORA) method when applied to designing a sheet metal flanging process. Surrogate models are used as less costly approximations to the computationally expensive Finite Element simulations

  20. Sustainable tourism as a method of forming a tolerant society

    Directory of Open Access Journals (Sweden)

    Dryga Svetlana

    2016-01-01

    Full Text Available The article concentrates on potential capabilities for the development of sustainable tourism, as well as its role in the formation of tolerant social relations. The authors revealed the profound impact of sustainable and hike tourism on emergence of the phenomenon ‘new tourist’. They also offered the description of levels of tolerance and their influence on the sustainable tendencies in modern tourism. There is a growing trend for tourism in modern international community to act as a high-powered regulator of socio-cultural relations and, simultaneously, as the crucial factor of counteraction to that xenophobia. A head-on clash of local and foreign cultures, which is an integral part of the very notion of tourism, is not supposed to assume itself in highly extreme forms, with the air of predominance of any of them, moreover, to be based on national, racial, religious, linguistic or educational differences. To put the idea across more efficiently, the authors resorted to exploiting such useful tools as the analysis and synthesis methodology, as well as that of comparison and prognostics. What is produced in the outcome of this study is revealing and emphasizing the levels of tolerance, characterizing the uneasy interrelationships between the so-called ‘new’ tourists and local community. The research findings could find practical applications for designing of new tourist products and elaborating of new networks of footpaths for walking tours.

  1. Colony shape as a genetic trait in the pattern-forming Bacillus mycoides

    Directory of Open Access Journals (Sweden)

    Pisaneschi Giuseppe

    2002-11-01

    Full Text Available Abstract Background Bacillus mycoides Flügge, a Gram-positive, non-motile soil bacterium assigned to Bacillus cereus group, grows on agar as chains of cells linked end to end, forming radial filaments curving clock- or counter-clockwise (SIN or DX morphotypes. The molecular mechanism causing asymmetric curving is not known: our working hypothesis considers regulation of filamentous growth as the prerequisite for these morphotypes. Results SIN and DX strains isolated from the environment were classified as B. mycoides by biochemical and molecular biology tests. Growth on agar of different hardness and nutrient concentration did not abolish colony patterns, nor was conversion between SIN and DX morphotypes ever noticed. A number of morphotype mutants, all originating from one SIN strain, were obtained. Some lost turn direction becoming fluffy, others became round and compact. All mutants lost wild type tight aggregation in liquid culture. Growth on agar was followed by microscopy, exploring the process of colony formation and details of cell divisions. A region of the dcw (division cell wall cluster, including ftsQ, ftsA, ftsZ and murC, was sequenced in DX and SIN strains as a basis for studying cell division. This confirmed the relatedness of DX and SIN strains to the B. cereus group. Conclusions DX and SIN asymmetric morphotypes stem from a close but not identical genomic context. Asymmetry is established early during growth on agar. Wild type bacilli construct mostly uninterrupted filaments with cells dividing at the free ends: they "walk" longer distances compared to mutants, where enhanced frequency of cell separation produces new growing edges resulting in round compact colonies.

  2. Method for forming biaxially textured articles by powder metallurgy

    Science.gov (United States)

    Goyal, Amit; Williams, Robert K.; Kroeger, Donald M.

    2002-01-01

    A method of preparing a biaxially textured alloy article comprises the steps of preparing a mixture comprising Ni powder and at least one powder selected from the group consisting of Cr, W, V, Mo, Cu, Al, Ce, YSZ, Y, Rare Earths, (RE), MgO, CeO.sub.2, and Y.sub.2 O.sub.3 ; compacting the mixture, followed by heat treating and rapidly recrystallizing to produce a biaxial texture on the article. In some embodiments the alloy article further comprises electromagnetic or electro-optical devices and possesses superconducting properties.

  3. A New Fast Vertical Method for Mining Frequent Patterns

    Directory of Open Access Journals (Sweden)

    Zhihong Deng

    2010-12-01

    Full Text Available Vertical mining methods are very effective for mining frequent patterns and usually outperform horizontal mining methods. However, the vertical methods become ineffective since the intersection time starts to be costly when the cardinality of tidset (tid-list or diffset is very large or there are a very large number of transactions. In this paper, we propose a novel vertical algorithm called PPV for fast frequent pattern discovery. PPV works based on a data structure called Node-lists, which is obtained from a coding prefix-tree called PPC-tree. The efficiency of PPV is achieved with three techniques. First, the Node-list is much more compact compared with previous proposed vertical structure (such as tid-lists or diffsets since transactions with common prefixes share the same nodes of the PPC-tree. Second, the counting of support is transformed into the intersection of Node-lists and the complexity of intersecting two Node-lists can be reduced to O(m+n by an efficient strategy, where m and n are the cardinalities of the two Node-lists respectively. Third, the ancestor-descendant relationship of two nodes, which is the basic step of intersecting Node-lists, can be very efficiently verified by Pre-Post codes of nodes. We experimentally compare our algorithm with FP-growth, and two prominent vertical algorithms (Eclat and dEclat on a number of databases. The experimental results show that PPV is an efficient algorithm that outperforms FP-growth, Eclat, and dEclat.

  4. Formation of Au nano-patterns on various substrates using simplified nano-transfer printing method

    Science.gov (United States)

    Kim, Jong-Woo; Yang, Ki-Yeon; Hong, Sung-Hoon; Lee, Heon

    2008-06-01

    For future device applications, fabrication of the metal nano-patterns on various substrates, such as Si wafer, non-planar glass lens and flexible plastic films become important. Among various nano-patterning technologies, nano-transfer print method is one of the simplest techniques to fabricate metal nano-patterns. In nano-transfer printing process, thin Au layer is deposited on flexible PDMS mold, containing surface protrusion patterns, and the Au layer is transferred from PDMS mold to various substrates due to the difference of bonding strength of Au layer to PDMS mold and to the substrate. For effective transfer of Au layer, self-assembled monolayer, which has strong bonding to Au, is deposited on the substrate as a glue layer. In this study, complicated SAM layer coating process was replaced to simple UV/ozone treatment, which can activates the surface and form the -OH radicals. Using simple UV/ozone treatments on both Au and substrate, Au nano-pattern can be successfully transferred to as large as 6 in. diameter Si wafer, without SAM coating process. High fidelity transfer of Au nano-patterns to non-planar glass lens and flexible PET film was also demonstrated.

  5. Method of forming a package for MEMS-based fuel cell

    Science.gov (United States)

    Morse, Jeffrey D; Jankowski, Alan F

    2013-05-21

    A MEMS-based fuel cell package and method thereof is disclosed. The fuel cell package comprises seven layers: (1) a sub-package fuel reservoir interface layer, (2) an anode manifold support layer, (3) a fuel/anode manifold and resistive heater layer, (4) a Thick Film Microporous Flow Host Structure layer containing a fuel cell, (5) an air manifold layer, (6) a cathode manifold support structure layer, and (7) a cap. Fuel cell packages with more than one fuel cell are formed by positioning stacks of these layers in series and/or parallel. The fuel cell package materials such as a molded plastic or a ceramic green tape material can be patterned, aligned and stacked to form three dimensional microfluidic channels that provide electrical feedthroughs from various layers which are bonded together and mechanically support a MEMS-based miniature fuel cell. The package incorporates resistive heating elements to control the temperature of the fuel cell stack. The package is fired to form a bond between the layers and one or more microporous flow host structures containing fuel cells are inserted within the Thick Film Microporous Flow Host Structure layer of the package.

  6. Analysis of the diffraction pattern obtained by the Laue method

    International Nuclear Information System (INIS)

    Riquet, J. par; Bonnet, R.

    1978-01-01

    A computation method is presented which allows a rapid indexing of any unknown spot pattern obtained by back-reflection or transmission Laue methods. The Cartesian coordinates of n spots are measured in an orthonormal frame referred to the photographic film. Two spots 1 and 2 separated by a wide angular distance αsup(m) are carefully chosen. Their indices are assumed to be less than 5. The set (E) of all the pairs of planes (h 1 k 1 l 1 ) and (h 2 k 2 l 2 ) making an angle α close to αsup(m) is then computed. Since the pair of reflecting planes related to spots 1 and 2 belongs to (E), each computed pair of planes is tried, in order to determine the orientation of the crystal and to check whether the coordinates of the (n-2) other spots can be matched to dense planes of indices less than 8. If the uncertainty of the measurements is high or if n is too low, this method gives the possible orientations for the crystal. Plane indices less than 8 have been identified in cubic, tetragonal and orthorhombic crystals. (Auth.)

  7. The study of forms of bonding marshmallow moisture with different composition by method of thermal analysis

    Directory of Open Access Journals (Sweden)

    G. O. Magomedov

    2017-01-01

    Full Text Available Marshmallow is a sugar confectionary product with increased sugar content and energy value because of the significant content of carbohydrates, in particular sugar-sand. The main drawback of marshmallow is the rapid process of its drying during storage due to the crystallization of sucrose and the gradual removal of moisture from the product. A method for obtaining marshmallow without sugar on the basis of high-conversion glucose syrup. In the work, experimental studies were carried out to determine the content and ratio of free and bound forms of moisture in marshmallow on the basis of sugars and on the basis of  high-conversion glucose syrup by Differential Scanning Calorimetry (DSC and Thermogravimetry (TG. To study the patterns of thermal effects on the properties of marshmallow samples, the non-isothermal analysis method and the synchronous thermal analysis instrument (TG-DTA / DSC of the STA 449 F3 Jupiter were used. In the process of thermal exposure, the samples decompose sugars and other organic compounds, as a result of which the sample weight decreases due to evaporation of moisture. The process of dehydration in a control sample of marshmallow using sugar occurs in a less wide temperature range than in a sample of marshmallow on the basis of  high-conversion glucose syrup, which indicates a greater degree of moisture bonding in the developed sample. A quantitative evaluation of the forms of moisture bonding in the samples was carried out using the experimental curves obtained by the TG method. From the temperature curves, the endothermic effects were determined, which correspond to the release of moisture with different forms and energies. Substitution of sugar for treacle in the formula of marshmallow reduces the share of free moisture and increases the safety of the product without signs of staling.

  8. Identification of DWI behavior patterns and methods for change

    Science.gov (United States)

    1982-09-01

    The purpose of this study was to identify patterns of behavior leading to driving while intoxicated (DWI), and to propose countermeasures for altering these patterns before they result in DWI. Two samples were studied: Los Angeles high school student...

  9. Optimization of control bars patterns and fuel recharges of coupled form

    International Nuclear Information System (INIS)

    Mejia S, D.M.; Ortiz S, J.J.

    2006-01-01

    In this work a system coupled for the optimization of fuel recharges and control bars patterns in boiling water reactors (BWR by its initials in English) is presented. It was used a multi state recurrent neural net like optimization technique. This type of neural net has been used in the solution of diverse problems, in particular the design of patterns of control bars and the design of the fuel recharge. However, these problems have been resolved in an independent way with different optimization techniques. The system was developed in FORTRAN 77 language, it calls OCORN (Optimization of Cycles of Operation using Neural Nets) and it solves both problems of combinatory optimization in a coupled way. OCORN begins creating a seed recharge by means of an optimization through the Haling principle. Later on a pattern of control bars for this recharge seed is proposed. Then a new fuel recharge is designed using the control bars patterns previously found. By this way an iterative process begins among the optimization of control bars patterns and the fuel recharge until a stop criteria it is completed. The stop criteria is completed when the fuel recharges and the control bars patterns don't vary in several successive iterations. The final result is an optimal fuel recharge and its respective control bars pattern. In this work the obtained results by this system for a cycle of balance of 18 months divided in 12 steps of burnt are presented. The obtained results are very encouraging, since the fuel recharge and the control bars pattern, its fulfill with the restrictions imposed in each one of the problems. (Author)

  10. Aesthetical Study of Patterns and Forms in the Metalworks during Seljuk Dynasty

    Directory of Open Access Journals (Sweden)

    Ashraf Sadat Mousavi Lar

    2017-06-01

    Full Text Available One of the brightest periods of Iranian art begins with the entrance of the Seljuk dynasty in the land. Metalwork and particularly the use of statues, gold and silver faces restrictions in the Islamic society which have influenced the basis of Seljuk traditional aesthetics. Metalwork is worth to be studied in order to understand basis of aesthetics of Seljuk figures and forms. This study has chosen twenty samples of metal works from Seljuk and Sasanid eras to get to know the aesthetic principles of Seljuk metalwork. Another inquiry of the paper is to grasp the differences between the metalwork of this era and pre-Islamic period. Research method has been a historical-descriptive and analytic-comparative one. The results show that tribal traditions rules Iranian-Islamic Seljuk metalwork and Islamic tradition has obtained the most frequency after comparisons were implemented. Used metals by the Seljuk respectively are silver, bronze, brass and copper. Construction and decoration techniques include chasing, [casting, engraving, niello (with equal statistics], inlaying, hammering, [embossing and open working]. Decorative figures include [floral and geometric figures along with inscriptions], animal, legendary and human figures.

  11. Urban expansion and transportation : the impact of urban form on commuting patterns on the city fringe of Beijing

    NARCIS (Netherlands)

    Zhao, Pengjun; Lue, Bin; de Roo, Gert

    2010-01-01

    A key issue in the development of China's growing megacities in the transport-related environmental costs due to rapid urban expansion. In light of this issue, the authors examine the impact of urban form on commuting patterns on the city fringe of Beijing. Based on household-survey data, the

  12. Tidal-induced large-scale regular bed form patterns in a three-dimensional shallow water model

    NARCIS (Netherlands)

    Hulscher, Suzanne J.M.H.

    1996-01-01

    The three-dimensional model presented in this paper is used to study how tidal currents form wave-like bottom patterns. Inclusion of vertical flow structure turns out to be necessary to describe the formation, or absence, of all known large-scale regular bottom features. The tide and topography are

  13. Development and Validation of a HPLC Method for the Determination of Lacidipine in Pure Form and in Pharmaceutical Dosage Form

    International Nuclear Information System (INIS)

    Vinodh, M.; Vinayak, M.; Rahul, K.; Pankaj, P.

    2012-01-01

    A simple and reliable high-performance liquid chromatography (HPLC) method was developed and validated for Lacidipine in pure form and pharmaceutical dosage form. The method was developed on X bridge C-18 column (150 mm x 4.6 mm, 5 μm) with a mobile phase gradient system of ammonium acetate and acetonitrile. The effluent was monitored by PDA detector at 240 nm. Calibration curve was linear over the concentration range of 50-250 μg/ml. For Intra-day and inter-day precision % RSD values were found to be 0.83 % and 0.41 % respectively. Recovery of Lacidipine was found to be in the range of 99.78-101.76 %. The limits of detection (LOD) and quantification (LOQ) were 1.0 and 7.3 μg/ml respectively. The developed RP-HPLC method was successfully applied for the quantitative determination of lacidipine in pharmaceutical dosage. (author)

  14. Using pattern analysis methods to do fast detection of manufacturing pattern failures

    Science.gov (United States)

    Zhao, Evan; Wang, Jessie; Sun, Mason; Wang, Jeff; Zhang, Yifan; Sweis, Jason; Lai, Ya-Chieh; Ding, Hua

    2016-03-01

    At the advanced technology node, logic design has become extremely complex and is getting more challenging as the pattern geometry size decreases. The small sizes of layout patterns are becoming very sensitive to process variations. Meanwhile, the high pressure of yield ramp is always there due to time-to-market competition. The company that achieves patterning maturity earlier than others will have a great advantage and a better chance to realize maximum profit margins. For debugging silicon failures, DFT diagnostics can identify which nets or cells caused the yield loss. But normally, a long time period is needed with many resources to identify which failures are due to one common layout pattern or structure. This paper will present a new yield diagnostic flow, based on preliminary EFA results, to show how pattern analysis can more efficiently detect pattern related systematic defects. Increased visibility on design pattern related failures also allows more precise yield loss estimation.

  15. Computational Analysis of G-Quadruplex Forming Sequences across Chromosomes Reveals High Density Patterns Near the Terminal Ends.

    Directory of Open Access Journals (Sweden)

    Julia H Chariker

    Full Text Available G-quadruplex structures (G4 are found throughout the human genome and are known to play a regulatory role in a variety of molecular processes. Structurally, they have many configurations and can form from one or more DNA strands. At the gene level, they regulate gene expression and protein synthesis. In this paper, chromosomal-level patterns of distribution are analyzed on the human genome to identify high-level distribution patterns potentially related to global functional processes. Here we show unique high density banding patterns on individual chromosomes that are highly correlated, appearing in a mirror pattern, across forward and reverse DNA strands. The highest density of G4 sequences occurs within four megabases of one end of most chromosomes and contains G4 motifs that bind with zinc finger proteins. These findings suggest that G4 may play a role in global chromosomal processes such as those found in meiosis.

  16. A biologically relevant method for considering patterns of oceanic retention in the Southern Ocean

    Science.gov (United States)

    Mori, Mao; Corney, Stuart P.; Melbourne-Thomas, Jessica; Klocker, Andreas; Sumner, Michael; Constable, Andrew

    2017-12-01

    Many marine species have planktonic forms - either during a larval stage or throughout their lifecycle - that move passively or are strongly influenced by ocean currents. Understanding these patterns of movement is important for informing marine ecosystem management and for understanding ecological processes generally. Retention of biological particles in a particular area due to ocean currents has received less attention than transport pathways, particularly for the Southern Ocean. We present a method for modelling retention time, based on the half-life for particles in a particular region, that is relevant for biological processes. This method uses geostrophic velocities at the ocean surface, derived from 23 years of satellite altimetry data (1993-2016), to simulate the advection of passive particles during the Southern Hemisphere summer season (from December to March). We assess spatial patterns in the retention time of passive particles and evaluate the processes affecting these patterns for the Indian sector of the Southern Ocean. Our results indicate that the distribution of retention time is related to bathymetric features and the resulting ocean dynamics. Our analysis also reveals a moderate level of consistency between spatial patterns of retention time and observations of Antarctic krill (Euphausia superba) distribution.

  17. Patterned microstructures formed with MeV Au implantation in Si(1 0 0)

    International Nuclear Information System (INIS)

    Rout, Bibhudutta; Greco, Richard R.; Zachry, Daniel P.; Dymnikov, Alexander D.; Glass, Gary A.

    2006-01-01

    Energetic (MeV) Au implantation in Si(1 0 0) (n-type) through masked micropatterns has been used to create layers resistant to KOH wet etching. Microscale patterns were produced in PMMA and SU(8) resist coatings on the silicon substrates using P-beam writing and developed. The silicon substrates were subsequently exposed using 1.5 MeV Au 3+ ions with fluences as high as 1 x 10 16 ions/cm 2 and additional patterns were exposed using copper scanning electron microscope calibration grids as masks on the silicon substrates. When wet etched with KOH microstructures were created in the silicon due to the resistance to KOH etching cause by the Au implantation. The process of combining the fabrication of masked patterns with P-beam writing with broad beam Au implantation through the masks can be a promising, cost-effective process for nanostructure engineering with Si

  18. Computational applications of the thermodynamic local potential: The case of pattern forming systems

    International Nuclear Information System (INIS)

    Hubert, J.Z.

    1986-09-01

    Using the thermodynamic local potential Φ a single variational principle may be formulated for a broad class of pattern formation phenomena (this class contains patterns which are: macroscopic, possess steady states, are degenerate at least with respect to one parameter, approach the steady state via fluctuations in the coarsely grained (macroscopic) phase space and so have no memory of the initial conditions). When a steady state is reached Φ assumes its minimum value with respect to distribution function and a maximum with respect to the actually assumed values of free parameters. (author)

  19. Patterns of retail location and urban form in Amsterdam in the mid-eighteenth century

    NARCIS (Netherlands)

    Lesger, C.

    2011-01-01

    In this article location theory is used to map and analyse the patterns of retail location in Amsterdam in the eighteenth century. In the city centre as well as along the main axes to markets and the city gates the retailing of shopping goods (textiles, consumer durables) was much more prominent

  20. Category Formation in Autism: Can Individuals with Autism Form Categories and Prototypes of Dot Patterns?

    Science.gov (United States)

    Gastgeb, Holly Zajac; Dundas, Eva M.; Minshew, Nancy J.; Strauss, Mark S.

    2012-01-01

    There is a growing amount of evidence suggesting that individuals with autism have difficulty with categorization. One basic cognitive ability that may underlie this difficulty is the ability to abstract a prototype. The current study examined prototype and category formation with dot patterns in high-functioning adults with autism and matched…

  1. Pattern Classification of Tropical Cyclone Tracks over the Western North Pacific using a Fuzzy Clustering Method

    Science.gov (United States)

    Kim, H.; Ho, C.; Kim, J.

    2008-12-01

    This study presents the pattern classification of tropical cyclone (TC) tracks over the western North Pacific (WNP) basin during the typhoon season (June through October) for 1965-2006 (total 42 years) using a fuzzy clustering method. After the fuzzy c-mean clustering algorithm to the TC trajectory interpolated into 20 segments of equivalent length, we divided the whole tracks into 7 patterns. The optimal number of the fuzzy cluster is determined by several validity measures. The classified TC track patterns represent quite different features in the recurving latitudes, genesis locations, and geographical pathways: TCs mainly forming in east-northern part of the WNP and striking Korean and Japan (C1); mainly forming in west-southern part of the WNP, traveling long pathway, and partly striking Japan (C2); mainly striking Taiwan and East China (C3); traveling near the east coast of Japan (C4); traveling the distant ocean east of Japan (C5); moving toward South China and Vietnam straightly (C6); and forming in the South China Sea (C7). Atmospheric environments related to each cluster show physically consistent with each TC track patterns. The straight track pattern is closely linked to a developed anticyclonic circulation to the north of the TC. It implies that this ridge acts as a steering flow forcing TCs to move to the northwest with a more west-oriented track. By contrast, recurving patterns occur commonly under the influence of the strong anomalous westerlies over the TC pathway but there definitely exist characteristic anomalous circulations over the mid- latitudes by pattern. Some clusters are closely related to the well-known large-scale phenomena. The C1 and C2 are highly related to the ENSO phase: The TCs in the C1 (C2) is more active during La Niña (El Niño). The TC activity in the C3 is associated with the WNP summer monsoon. The TCs in the C4 is more (less) vigorous during the easterly (westerly) phase of the stratospheric quasi-biennial oscillation

  2. Numerical method for studying the circulation patterns of a fluid in a cavity

    International Nuclear Information System (INIS)

    Stephani, L.M.; Butler, T.D.

    1975-10-01

    The method incorporates three circulation-inducing mechanisms: (1) buoyancy induced by nonuniform initial distribution of heat throughout the fluid, (2) buoyancy induced by removal of heat from the fluid, and (3) forced convection induced by withdrawal of heated fluid and return of cooled fluid. A two-dimensional computer program, CIRCO, based on the Marker-and-Cell (MAC) technique, is used to study the circulation patterns. The report discusses the code and illustrates its capabilities by means of examples from studies conducted for the Pacer project, which investigates the concept of producing electrical power from energy released by thermonuclear explosions in a salt dome. Efficient engineering for withdrawing energy from the cavity requires an understanding of the circulation patterns of the heated fluid. CIRCO provides this information in the form of computer-generated plots

  3. Methods for Improving the Diagnosis of a Brugada ECG Pattern.

    Science.gov (United States)

    Gottschalk, Byron H; Garcia-Niebla, Javier; Anselm, Daniel D; Glover, Benedict; Baranchuk, Adrian

    2016-03-01

    Brugada syndrome (BrS) is an inherited channelopathy that predisposes individuals to malignant arrhythmias and can lead to sudden cardiac death. The condition is characterized by two electrocardiography (ECG) patterns: the type-1 or "coved" ECG and the type-2 or "saddleback" ECG. Although the type-1 Brugada ECG pattern is diagnostic for the condition, the type-2 Brugada ECG pattern requires differential diagnosis from conditions that produce a similar morphology. In this article, we present a case that is suspicious but not diagnostic for BrS and discuss the application of ECG methodologies for increasing or decreasing suspicion for a diagnosis of BrS. © 2015 Wiley Periodicals, Inc.

  4. THE PRODUCTION OF COMPLEX PROFILE DETAILS BY COMBINED METHOD OF LOST-WAX CASTING AND OF CONSUMABLE PATTERN MODELS

    Directory of Open Access Journals (Sweden)

    O. I. Shinsky

    2016-01-01

    Full Text Available The technological process of receiving figurine castings of a heat resisting alloy HN57KTVYuMBL brand developed and tested by authors a combined method of oflost-wax casting (pouring gate system and of consumable expanded polystyrene pattern in shell forms kompleks modify ceramics promotes decrease in crack formation of forms at the expense of correctly picked up temperature and time mode of annealing of a form with model. Besides this method allows to receive figurine castings with minimization of an allowance for machining of details, to increase their geometrical accuracy and to lower a roughness.

  5. a Three-Step Spatial-Temporal Clustering Method for Human Activity Pattern Analysis

    Science.gov (United States)

    Huang, W.; Li, S.; Xu, S.

    2016-06-01

    How people move in cities and what they do in various locations at different times form human activity patterns. Human activity pattern plays a key role in in urban planning, traffic forecasting, public health and safety, emergency response, friend recommendation, and so on. Therefore, scholars from different fields, such as social science, geography, transportation, physics and computer science, have made great efforts in modelling and analysing human activity patterns or human mobility patterns. One of the essential tasks in such studies is to find the locations or places where individuals stay to perform some kind of activities before further activity pattern analysis. In the era of Big Data, the emerging of social media along with wearable devices enables human activity data to be collected more easily and efficiently. Furthermore, the dimension of the accessible human activity data has been extended from two to three (space or space-time) to four dimensions (space, time and semantics). More specifically, not only a location and time that people stay and spend are collected, but also what people "say" for in a location at a time can be obtained. The characteristics of these datasets shed new light on the analysis of human mobility, where some of new methodologies should be accordingly developed to handle them. Traditional methods such as neural networks, statistics and clustering have been applied to study human activity patterns using geosocial media data. Among them, clustering methods have been widely used to analyse spatiotemporal patterns. However, to our best knowledge, few of clustering algorithms are specifically developed for handling the datasets that contain spatial, temporal and semantic aspects all together. In this work, we propose a three-step human activity clustering method based on space, time and semantics to fill this gap. One-year Twitter data, posted in Toronto, Canada, is used to test the clustering-based method. The results show that the

  6. A THREE-STEP SPATIAL-TEMPORAL-SEMANTIC CLUSTERING METHOD FOR HUMAN ACTIVITY PATTERN ANALYSIS

    Directory of Open Access Journals (Sweden)

    W. Huang

    2016-06-01

    Full Text Available How people move in cities and what they do in various locations at different times form human activity patterns. Human activity pattern plays a key role in in urban planning, traffic forecasting, public health and safety, emergency response, friend recommendation, and so on. Therefore, scholars from different fields, such as social science, geography, transportation, physics and computer science, have made great efforts in modelling and analysing human activity patterns or human mobility patterns. One of the essential tasks in such studies is to find the locations or places where individuals stay to perform some kind of activities before further activity pattern analysis. In the era of Big Data, the emerging of social media along with wearable devices enables human activity data to be collected more easily and efficiently. Furthermore, the dimension of the accessible human activity data has been extended from two to three (space or space-time to four dimensions (space, time and semantics. More specifically, not only a location and time that people stay and spend are collected, but also what people “say” for in a location at a time can be obtained. The characteristics of these datasets shed new light on the analysis of human mobility, where some of new methodologies should be accordingly developed to handle them. Traditional methods such as neural networks, statistics and clustering have been applied to study human activity patterns using geosocial media data. Among them, clustering methods have been widely used to analyse spatiotemporal patterns. However, to our best knowledge, few of clustering algorithms are specifically developed for handling the datasets that contain spatial, temporal and semantic aspects all together. In this work, we propose a three-step human activity clustering method based on space, time and semantics to fill this gap. One-year Twitter data, posted in Toronto, Canada, is used to test the clustering-based method. The

  7. Reactor noise analysis by statistical pattern recognition methods

    International Nuclear Information System (INIS)

    Howington, L.C.; Gonzalez, R.C.

    1976-01-01

    A multivariate statistical pattern recognition system for reactor noise analysis is presented. The basis of the system is a transformation for decoupling correlated variables and algorithms for inferring probability density functions. The system is adaptable to a variety of statistical properties of the data, and it has learning, tracking, updating, and data compacting capabilities. System design emphasizes control of the false-alarm rate. Its abilities to learn normal patterns, to recognize deviations from these patterns, and to reduce the dimensionality of data with minimum error were evaluated by experiments at the Oak Ridge National Laboratory (ORNL) High-Flux Isotope Reactor. Power perturbations of less than 0.1 percent of the mean value in selected frequency ranges were detected by the pattern recognition system

  8. 48 CFR 215.404-70 - DD Form 1547, Record of Weighted Guidelines Method Application.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false DD Form 1547, Record of... TYPES CONTRACTING BY NEGOTIATION Contract Pricing 215.404-70 DD Form 1547, Record of Weighted Guidelines Method Application. Follow the procedures at PGI 215.404-70 for use of DD Form 1547 whenever a structured...

  9. Basic sculpturing methods as innovatory incentives in the development of aesthetic form concepts

    DEFF Research Database (Denmark)

    Thomsen, Bente Dahl

    2009-01-01

      Many project teams grapple for a long time with developing ideas to the form concept because of a lack of methods to solve the many form problems they face in sketching. They also have difficulty in translating the project requirements for product proportions or volumes to an aesthetic form...

  10. Two dimensional Fourier transform methods for fringe pattern analysis

    Science.gov (United States)

    Sciammarella, C. A.; Bhat, G.

    An overview of the use of FFTs for fringe pattern analysis is presented, with emphasis on fringe patterns containing displacement information. The techniques are illustrated via analysis of the displacement and strain distributions in the direction perpendicular to the loading, in a disk under diametral compression. The experimental strain distribution is compared to the theoretical, and the agreement is found to be excellent in regions where the elasticity solution models well the actual problem.

  11. Light emitting diode with high aspect ratio submicron roughness for light extraction and methods of forming

    Science.gov (United States)

    Li, Ting [Ventura, CA

    2011-04-26

    The surface morphology of an LED light emitting surface is changed by applying a reactive ion etch (RIE) process to the light emitting surface. High aspect ratio, submicron roughness is formed on the light emitting surface by transferring a thin film metal hard-mask having submicron patterns to the surface prior to applying a reactive ion etch process. The submicron patterns in the metal hard-mask can be formed using a low cost, commercially available nano-patterned template which is transferred to the surface with the mask. After subsequently binding the mask to the surface, the template is removed and the RIE process is applied for time duration sufficient to change the morphology of the surface. The modified surface contains non-symmetric, submicron structures having high aspect ratio which increase the efficiency of the device.

  12. Method of forming a ceramic matrix composite and a ceramic matrix component

    Science.gov (United States)

    de Diego, Peter; Zhang, James

    2017-05-30

    A method of forming a ceramic matrix composite component includes providing a formed ceramic member having a cavity, filling at least a portion of the cavity with a ceramic foam. The ceramic foam is deposited on a barrier layer covering at least one internal passage of the cavity. The method includes processing the formed ceramic member and ceramic foam to obtain a ceramic matrix composite component. Also provided is a method of forming a ceramic matrix composite blade and a ceramic matrix composite component.

  13. Method of forming electronically conducting polymers on conducting and nonconducting substrates

    Science.gov (United States)

    Murphy, Oliver J. (Inventor); Hitchens, G. Duncan (Inventor); Hodko, Dalibor (Inventor); Clarke, Eric T. (Inventor); Miller, David L. (Inventor); Parker, Donald L. (Inventor)

    2001-01-01

    The present invention provides electronically conducting polymer films formed from photosensitive formulations of pyrrole and an electron acceptor that have been selectively exposed to UV light, laser light, or electron beams. The formulations may include photoinitiators, flexibilizers, solvents and the like. These solutions can be used in applications including printed circuit boards and through-hole plating and enable direct metallization processes on non-conducting substrates. After forming the conductive polymer patterns, a printed wiring board can be formed by sensitizing the polymer with palladium and electrolytically depositing copper.

  14. Methods of forming and realization of assortment policy of retail business enterprises

    Directory of Open Access Journals (Sweden)

    Kudenko Kiril

    2016-07-01

    Full Text Available Within the framework of the article systematisation of methods of forming and realisation of assortment policy of enterprises of retail business is done. Recommendations concerning the priority of the use of separate methods of forming and realisation of assortment policy with different purposes, taking into account their content, advantages and disadvantages are developed.

  15. Wafer-Level Packaging Method for RF MEMS Applications Using Pre-Patterned BCB Polymer

    Directory of Open Access Journals (Sweden)

    Zhuhao Gong

    2018-02-01

    Full Text Available A radio-frequency micro-electro-mechanical system (RF MEMS wafer-level packaging (WLP method using pre-patterned benzo-cyclo-butene (BCB polymers with a high-resistivity silicon cap is proposed to achieve high bonding quality and excellent RF performance. In this process, the BCB polymer was pre-defined to form the sealing ring and bonding layer by the spin-coating and patterning of photosensitive BCB before the cavity formation. During anisotropic wet etching of the silicon wafer to generate the housing cavity, the BCB sealing ring was protected by a sputtered Cr/Au (chromium/gold layer. The average measured thickness of the BCB layer was 5.9 μm. In contrast to the conventional methods of spin-coating BCB after fabricating cavities, the pre-patterned BCB method presented BCB bonding layers with better quality on severe topography surfaces in terms of increased uniformity of thickness and better surface flatness. The observation of the bonded layer showed that no void or gap formed on the protruding coplanar waveguide (CPW lines. A shear strength test was experimentally implemented as a function of the BCB widths in the range of 100–400 μm. The average shear strength of the packaged device was higher than 21.58 MPa. A RF MEMS switch was successfully packaged using this process with a negligible impact on the microwave characteristics and a significant improvement in the lifetime from below 10 million to over 1 billion. The measured insertion loss of the packaged RF MEMS switch was 0.779 dB and the insertion loss deterioration caused by the package structure was less than 0.2 dB at 30 GHz.

  16. Effect of fabric mounting method and backing material on bloodstain patterns of drip stains on textiles.

    Science.gov (United States)

    Chang, J Y M; Michielsen, S

    2016-05-01

    Textiles may provide valuable bloodstain evidence to help piece together events or activities at violent crime scenes. However, in spite of over 75 years of research, there are still difficulties encountered in many cases in the interpretation and identification of bloodstains on textiles. In this study, we dripped porcine blood onto three types of fabric (plain woven, single jersey knit, and denim) that are supported in four different ways (hard, taut, loose, and semi-hard, i.e., fabric laid on denim). These four mounting methods represent different ways in which a textile may be present when blood from a violent act lands on it. This study investigates how the fabric mounting method and backing material affect the appearance of drip stains on textiles. We found that bloodstain patterns formed on fabric lying flat on a hard surface were very different from when the same fabric was suspended loosely. We also found that bloodstains formed on the technical back of single jersey knit were vastly different from those on the technical face. Interestingly, some drip stains showed blood passing through the textile and leaving a stain behind it that resembled insect stains. By observing, recording, and describing how a blood stained textile is found or presented at the scene, the analyst may be able to better understand bloodstains and bloodstain patterns on textiles, which could be useful to confirm or refute a witness's account of how blood came to be where it was found after a bloodshed event.

  17. Composite materials and bodies including silicon carbide and titanium diboride and methods of forming same

    Science.gov (United States)

    Lillo, Thomas M.; Chu, Henry S.; Harrison, William M.; Bailey, Derek

    2013-01-22

    Methods of forming composite materials include coating particles of titanium dioxide with a substance including boron (e.g., boron carbide) and a substance including carbon, and reacting the titanium dioxide with the substance including boron and the substance including carbon to form titanium diboride. The methods may be used to form ceramic composite bodies and materials, such as, for example, a ceramic composite body or material including silicon carbide and titanium diboride. Such bodies and materials may be used as armor bodies and armor materials. Such methods may include forming a green body and sintering the green body to a desirable final density. Green bodies formed in accordance with such methods may include particles comprising titanium dioxide and a coating at least partially covering exterior surfaces thereof, the coating comprising a substance including boron (e.g., boron carbide) and a substance including carbon.

  18. Sidewall patterning - A new wafer-scale method for accurate patterning of vertical silicon structures

    NARCIS (Netherlands)

    Westerik, P. J.; Vijselaar, W. J.C.; Berenschot, J. W.; Tas, N. R.; Huskens, J.; Gardeniers, J. G.E.

    2018-01-01

    For the definition of wafer scale micro- and nanostructures, in-plane geometry is usually controlled by optical lithography. However, options for precisely patterning structures in the out-of-plane direction are much more limited. In this paper we present a versatile self-aligned technique that

  19. First applications of structural pattern recognition methods to the investigation of specific physical phenomena at JET

    International Nuclear Information System (INIS)

    Ratta, G.A.; Vega, J.; Pereira, A.; Portas, A.; Luna, E. de la; Dormido-Canto, S.; Farias, G.; Dormido, R.; Sanchez, J.; Duro, N.; Vargas, H.; Santos, M.; Pajares, G.; Murari, A.

    2008-01-01

    Structural pattern recognition techniques allow the identification of plasma behaviours. Physical properties are encoded in the morphological structure of signals. Intelligent access methods have been applied to JET databases to retrieve data according to physical criteria. On the one hand, the structural form of signals has been used to develop general purpose data retrieval systems to search for both similar entire waveforms and similar structural shapes inside waveforms. On the other hand, domain dependent knowledge was added to the structural information of signals to create particular data retrieval methods for specific physical phenomena. The inclusion of explicit knowledge assists in data analysis. The latter has been applied in JET to look for first, cut-offs in ECE heterodyne radiometer signals and, second, L-H transitions

  20. First applications of structural pattern recognition methods to the investigation of specific physical phenomena at JET

    Energy Technology Data Exchange (ETDEWEB)

    Ratta, G.A. [Asociacion EURATOM/CIEMAT para Fusion (Spain)], E-mail: giuseppe.ratta@ciemat.es; Vega, J.; Pereira, A.; Portas, A.; Luna, E. de la [Asociacion EURATOM/CIEMAT para Fusion (Spain); Dormido-Canto, S.; Farias, G.; Dormido, R.; Sanchez, J.; Duro, N.; Vargas, H. [Dpto. Informatica y Automatica-UNED, 28040 Madrid (Spain); Santos, M.; Pajares, G. [Dpto. Arquitectura de Computadores y Automatica-UCM, 28040 Madrid (Spain); Murari, A. [Consorzio RFX-Associazione EURATOM ENEA per la Fusione, Padua (Italy)

    2008-04-15

    Structural pattern recognition techniques allow the identification of plasma behaviours. Physical properties are encoded in the morphological structure of signals. Intelligent access methods have been applied to JET databases to retrieve data according to physical criteria. On the one hand, the structural form of signals has been used to develop general purpose data retrieval systems to search for both similar entire waveforms and similar structural shapes inside waveforms. On the other hand, domain dependent knowledge was added to the structural information of signals to create particular data retrieval methods for specific physical phenomena. The inclusion of explicit knowledge assists in data analysis. The latter has been applied in JET to look for first, cut-offs in ECE heterodyne radiometer signals and, second, L-H transitions.

  1. Application of the moving frame method to deformed Willmore surfaces in space forms

    Science.gov (United States)

    Paragoda, Thanuja

    2018-06-01

    The main goal of this paper is to use the theory of exterior differential forms in deriving variations of the deformed Willmore energy in space forms and study the minimizers of the deformed Willmore energy in space forms. We derive both first and second order variations of deformed Willmore energy in space forms explicitly using moving frame method. We prove that the second order variation of deformed Willmore energy depends on the intrinsic Laplace Beltrami operator, the sectional curvature and some special operators along with mean and Gauss curvatures of the surface embedded in space forms, while the first order variation depends on the extrinsic Laplace Beltrami operator.

  2. Nodal methods for calculating nuclear reactor transients, control rod patterns, and fuel pin powers

    International Nuclear Information System (INIS)

    Cho, Byungoh.

    1990-01-01

    Nodal methods which are used to calculate reactor transients, control rod patterns, and fuel pin powers are investigated. The 3-D nodal code, STORM, has been modified to perform these calculations. Several numerical examples lead to the following conclusions: (1) By employing a thermal leakage-to-absorption ratio (TLAR) approximation for the spatial shape of the thermal fluxes for the 3-D Langenbuch-Maurer-Werner (LMW) and the superprompt critical transient problems, the convergence of the conventional two-group scheme is accelerated. (2) By employing the steepest-ascent hill climbing search with heuristic strategies, Optimum Control Rod Pattern Searcher (OCRPS) is developed for solving control rod positioning problem in BWRs. Using the method of approximation programming the objective function and the nuclear and thermal-hydraulic constraints are modified as heuristic functions that guide the search. The test calculations have demonstrated that, for the first cycle of the Edwin Hatch Unit number-sign 2 reactor, OCRPS shows excellent performance for finding a series of optimum control rod patterns for six burnup steps during the operating cycle. (3) For the modified two-dimensional EPRI-9R problem, the least square second-order polynomial flux expansion method was demonstrated to be computationally about 30 times faster than a fine-mesh finite difference calculation in order to achieve comparable accuracy for pin powers. The basic assumption of this method is that the reconstructed flux can be expressed as a product of an assembly form function and a second-order polynomial function

  3. The Fractal Patterns of Words in a Text: A Method for Automatic Keyword Extraction.

    Science.gov (United States)

    Najafi, Elham; Darooneh, Amir H

    2015-01-01

    A text can be considered as a one dimensional array of words. The locations of each word type in this array form a fractal pattern with certain fractal dimension. We observe that important words responsible for conveying the meaning of a text have dimensions considerably different from one, while the fractal dimensions of unimportant words are close to one. We introduce an index quantifying the importance of the words in a given text using their fractal dimensions and then ranking them according to their importance. This index measures the difference between the fractal pattern of a word in the original text relative to a shuffled version. Because the shuffled text is meaningless (i.e., words have no importance), the difference between the original and shuffled text can be used to ascertain degree of fractality. The degree of fractality may be used for automatic keyword detection. Words with the degree of fractality higher than a threshold value are assumed to be the retrieved keywords of the text. We measure the efficiency of our method for keywords extraction, making a comparison between our proposed method and two other well-known methods of automatic keyword extraction.

  4. The Fractal Patterns of Words in a Text: A Method for Automatic Keyword Extraction

    Science.gov (United States)

    Najafi, Elham; Darooneh, Amir H.

    2015-01-01

    A text can be considered as a one dimensional array of words. The locations of each word type in this array form a fractal pattern with certain fractal dimension. We observe that important words responsible for conveying the meaning of a text have dimensions considerably different from one, while the fractal dimensions of unimportant words are close to one. We introduce an index quantifying the importance of the words in a given text using their fractal dimensions and then ranking them according to their importance. This index measures the difference between the fractal pattern of a word in the original text relative to a shuffled version. Because the shuffled text is meaningless (i.e., words have no importance), the difference between the original and shuffled text can be used to ascertain degree of fractality. The degree of fractality may be used for automatic keyword detection. Words with the degree of fractality higher than a threshold value are assumed to be the retrieved keywords of the text. We measure the efficiency of our method for keywords extraction, making a comparison between our proposed method and two other well-known methods of automatic keyword extraction. PMID:26091207

  5. Phylogeography of competing sexual and parthenogenetic forms of a freshwater flatworm: patterns and explanations

    Directory of Open Access Journals (Sweden)

    Carranza Salvador

    2003-11-01

    Full Text Available Abstract Background Models of the maintenance of sex predict that one reproductive strategy, sexual or parthenogenetic, should outcompete the other. Distribution patterns may reflect the outcome of this competition as well as the effect of chance and historical events. We review the distribution data of sexual and parthenogenetic biotypes of the planarian Schmidtea polychroa. Results S. polychroa lives in allopatry or sympatry across Europe except for Central and North-Western Europe, where sexual individuals have never been reported. A phylogenetic relationship between 36 populations based on a 385 bp fragment of the mitochondrial cytochrome oxidase I gene revealed that haplotypes were often similar over large geographic distances. In North Italian lakes, however, diversity was extreme, with sequence differences of up to 5% within the same lake in both sexuals and parthenogens. Mixed populations showed "endemic" parthenogenetic lineages that presumably originated from coexisting sexuals, and distantly related ones that probably result from colonization by parthenogens independent from sexuals. Conclusions Parthenogens originated repeatedly from sexuals, mainly in Italy, but the same may apply to other Mediterranean regions (Spain, Greece. The degree of divergence between populations suggests that S. polychroa survived the ice ages in separate ice-free areas in Central, Eastern and Southern Europe and re-colonised Europe after the retreat of the major glaciers. Combining these results with those based on nuclear markers, the data suggest that repeated hybridisation between sexuals and parthenogenetic lineages in mixed populations maintains high levels of genetic diversity in parthenogens. This can explain why parthenogens persist in populations that were originally sexual. Exclusive parthenogenesis in central and western populations suggests better colonisation capacity, possibly because of inbreeding costs as well as hybridisation of sexuals

  6. A knowledge based method for nuclear plant loading pattern determination

    International Nuclear Information System (INIS)

    Dauboin, P.

    1990-01-01

    This paper deals with the design of a knowledge based system for solving an industrial problem which occurs in nuclear fuel management. The problem lies in determining satisfactory loading patterns for nuclear plants. Its primary feature consists in the huge search space involved. Conventional resolution processes are formally defined and analyzed: there is no general algorithm which guarantees to always provide a reasonable solution in each situation. We propose a new approach to solve this constrained search problem using domain-specific knowledge and general constraint-based heuristics. During a preprocessing step, a problem dependent search algorithm is designed. This procedure is then automatically implemented in FORTRAN. The generated routines have proved to be very efficient finding solutions which could not have been provided using logic programming. A prototype expert system has already been applied to actual reload pattern searches. While combining efficiency and flexibility, this knowledge based system enables human experts to rapidly match new constraints and requirements

  7. A pattern-based method to automate mask inspection files

    Science.gov (United States)

    Kamal Baharin, Ezni Aznida Binti; Muhsain, Mohamad Fahmi Bin; Ahmad Ibrahim, Muhamad Asraf Bin; Ahmad Noorhani, Ahmad Nurul Ihsan Bin; Sweis, Jason; Lai, Ya-Chieh; Hurat, Philippe

    2017-03-01

    Mask inspection is a critical step in the mask manufacturing process in order to ensure all dimensions printed are within the needed tolerances. This becomes even more challenging as the device nodes shrink and the complexity of the tapeout increases. Thus, the amount of measurement points and their critical dimension (CD) types are increasing to ensure the quality of the mask. In addition to the mask quality, there is a significant amount of manpower needed when the preparation and debugging of this process are not automated. By utilizing a novel pattern search technology with the ability to measure and report match region scan-line (edge) measurements, we can create a flow to find, measure and mark all metrology locations of interest and provide this automated report to the mask shop for inspection. A digital library is created based on the technology product and node which contains the test patterns to be measured. This paper will discuss how these digital libraries will be generated and then utilized. As a time-critical part of the manufacturing process, this can also reduce the data preparation cycle time, minimize the amount of manual/human error in naming and measuring the various locations, reduce the risk of wrong/missing CD locations, and reduce the amount of manpower needed overall. We will also review an example pattern and how the reporting structure to the mask shop can be processed. This entire process can now be fully automated.

  8. Form gene clustering method about pan-ethnic-group products based on emotional semantic

    Science.gov (United States)

    Chen, Dengkai; Ding, Jingjing; Gao, Minzhuo; Ma, Danping; Liu, Donghui

    2016-09-01

    The use of pan-ethnic-group products form knowledge primarily depends on a designer's subjective experience without user participation. The majority of studies primarily focus on the detection of the perceptual demands of consumers from the target product category. A pan-ethnic-group products form gene clustering method based on emotional semantic is constructed. Consumers' perceptual images of the pan-ethnic-group products are obtained by means of product form gene extraction and coding and computer aided product form clustering technology. A case of form gene clustering about the typical pan-ethnic-group products is investigated which indicates that the method is feasible. This paper opens up a new direction for the future development of product form design which improves the agility of product design process in the era of Industry 4.0.

  9. Design Patterns for Mixed-Method Research in HCI

    NARCIS (Netherlands)

    Robert Holwerda; Arthur Bennis; Lambert Zaad; René Bakker; Sabine Craenmehr; Stijn Hoppenbrouwers; Dick Lenior; Marjolein Jacobs; Koen van Turnhout; Ralph Niels

    2014-01-01

    In this paper we discuss mixed-method research in HCI. We report on an empirical literature study of the NordiCHI 2012 proceedings which aimed to uncover and describe common mixed-method approaches, and to identify good practices for mixed-methods research in HCI. We present our results as

  10. Crystallization and diffraction patterns of the oxy and cyano forms of the Lucina pectinata haemoglobins complex

    International Nuclear Information System (INIS)

    Ruiz-Martínez, Carlos R.; Nieves-Marrero, Carlos A.; Estremera-Andújar, Rafael A.; Gavira, José A.; González-Ramírez, Luis A.; López-Garriga, Juan; García-Ruiz, Juan M.

    2008-01-01

    The native oxygen-carrier haemoglobins complex (HbII–III) is composed of haemoglobin II (HbII) and haemoglobin III (HbIII), which are found in the ctenidia tissue of the bivalve mollusc Lucina pectinata. This protein complex was isolated and purified from its natural source and crystallized using the vapour-diffusion and capillary counter-diffusion methods. The native oxygen-carrier haemoglobins complex (HbII–III) is composed of haemoglobin II (HbII) and haemoglobin III (HbIII), which are found in the ctenidia tissue of the bivalve mollusc Lucina pectinata. This protein complex was isolated and purified from its natural source and crystallized using the vapour-diffusion and capillary counter-diffusion methods. Oxy and cyano derivatives of the complex crystallized using several conditions, but the best crystals in terms of quality and size were obtained from sodium formate pH 5 using the counter-diffusion method in a single capillary. Crystals of the oxy and cyano complexes, which showed a ruby-red colour and nonsingular prismatic shapes, scattered X-rays to resolution limits of 2.15 and 2.20 Å, respectively, using a 0.886 Å synchrotron-radiation source. The crystals belonged to the tetragonal system, space group P4 2 2 1 2, with unit-cell parameters a = b = 74.07, c = 152.07 and a = b = 73.83, c = 152.49 Å for the oxy and cyano complexes, respectively. The asymmetric unit of both crystals is composed of a single copy of the heterodimer, with Matthew coefficients (V M ) of 3.08 and 3.06 Å 3 Da −1 for the oxy and cyano complexes, respectively, which correspond to a solvent content of approximately 60.0% by volume

  11. Random walk-based similarity measure method for patterns in complex object

    Directory of Open Access Journals (Sweden)

    Liu Shihu

    2017-04-01

    Full Text Available This paper discusses the similarity of the patterns in complex objects. The complex object is composed both of the attribute information of patterns and the relational information between patterns. Bearing in mind the specificity of complex object, a random walk-based similarity measurement method for patterns is constructed. In this method, the reachability of any two patterns with respect to the relational information is fully studied, and in the case of similarity of patterns with respect to the relational information can be calculated. On this bases, an integrated similarity measurement method is proposed, and algorithms 1 and 2 show the performed calculation procedure. One can find that this method makes full use of the attribute information and relational information. Finally, a synthetic example shows that our proposed similarity measurement method is validated.

  12. Application of normal form methods to the analysis of resonances in particle accelerators

    International Nuclear Information System (INIS)

    Davies, W.G.

    1992-01-01

    The transformation to normal form in a Lie-algebraic framework provides a very powerful method for identifying and analysing non-linear behaviour and resonances in particle accelerators. The basic ideas are presented and illustrated. (author). 4 refs

  13. Patterned structures of graphene and graphitic carbon and methods for their manufacture

    Energy Technology Data Exchange (ETDEWEB)

    Polsky, Ronen; Xiao, Xiaoyin; Burckel, David Bruce; Wheeler, David R.; Brozik, Susan M.; Beechem, Thomas Edwin

    2018-01-09

    A patterned graphene or graphitic body is produced by providing a three-dimensionally patterned carbonaceous body; coating the body with a catalytic metal whereby is formed a coating having an inner surface proximal the body and an outer surface distal the body; and annealing the coated body under time and temperature conditions effective to form a graphene or graphitic layer on the outer surface of the catalytic metal coating.

  14. Within-twig leaf distribution patterns differ among plant life-forms in a subtropical Chinese forest.

    Science.gov (United States)

    Meng, Fengqun; Cao, Rui; Yang, Dongmei; Niklas, Karl J; Sun, Shucun

    2013-07-01

    Amax) had more even leaf distribution patterns than evergreen species (which had low LCP, LSP and Amax); shade-adapted evergreen species had more even leaf distribution patterns than sun-adapted evergreen species. We propose that the leaf distribution pattern (i.e., 'evenness' CV, which is an easily measured functional trait) can be used to distinguish among life-forms in communities similar to the one examined in this study.

  15. Foam patterns

    Science.gov (United States)

    Chaudhry, Anil R; Dzugan, Robert; Harrington, Richard M; Neece, Faurice D; Singh, Nipendra P; Westendorf, Travis

    2013-11-26

    A method of creating a foam pattern comprises mixing a polyol component and an isocyanate component to form a liquid mixture. The method further comprises placing a temporary core having a shape corresponding to a desired internal feature in a cavity of a mold and inserting the mixture into the cavity of the mold so that the mixture surrounds a portion of the temporary core. The method optionally further comprises using supporting pins made of foam to support the core in the mold cavity, with such pins becoming integral part of the pattern material simplifying subsequent processing. The method further comprises waiting for a predetermined time sufficient for a reaction from the mixture to form a foam pattern structure corresponding to the cavity of the mold, wherein the foam pattern structure encloses a portion of the temporary core and removing the temporary core from the pattern independent of chemical leaching.

  16. THE METHOD OF CONSTRUCTING A BOOLEAN FORMULA OF A POLYGON IN THE DISJUNCTIVE NORMAL FORM

    Directory of Open Access Journals (Sweden)

    A. A. Butov

    2014-01-01

    Full Text Available The paper focuses on finalizing the method of finding a polygon Boolean formula in disjunctive normal form, described in the previous article [1]. An improved method eliminates the drawback asso-ciated with the existence of a class of problems for which the solution is only approximate. The pro-posed method always allows to find an exact solution. The method can be used, in particular, in the systems of computer-aided design of integrated circuits topology.

  17. What makes a pattern? Matching decoding methods to data in multivariate pattern analysis

    Directory of Open Access Journals (Sweden)

    Philip A Kragel

    2012-11-01

    Full Text Available Research in neuroscience faces the challenge of integrating information across different spatial scales of brain function. A promising technique for harnessing information at a range of spatial scales is multivariate pattern analysis (MVPA of functional magnetic resonance imaging (fMRI data. While the prevalence of MVPA has increased dramatically in recent years, its typical implementations for classification of mental states utilize only a subset of the information encoded in local fMRI signals. We review published studies employing multivariate pattern classification since the technique’s introduction, which reveal an extensive focus on the improved detection power that linear classifiers provide over traditional analysis techniques. We demonstrate using simulations and a searchlight approach, however, that nonlinear classifiers are capable of extracting distinct information about interactions within a local region. We conclude that for spatially localized analyses, such as searchlight and region of interest, multiple classification approaches should be compared in order to match fMRI analyses to the properties of local circuits.

  18. Neutron absorbers and methods of forming at least a portion of a neutron absorber

    Energy Technology Data Exchange (ETDEWEB)

    Guillen, Donna P; Porter, Douglas L; Swank, W David; Erickson, Arnold W

    2014-12-02

    Methods of forming at least a portion of a neutron absorber include combining a first material and a second material to form a compound, reducing the compound into a plurality of particles, mixing the plurality of particles with a third material, and pressing the mixture of the plurality of particles and the third material. One or more components of neutron absorbers may be formed by such methods. Neutron absorbers may include a composite material including an intermetallic compound comprising hafnium aluminide and a matrix material comprising pure aluminum.

  19. Adaptive Forming of the Beam Pattern of Microstrip Antenna with the Use of an Artificial Neural Network

    Directory of Open Access Journals (Sweden)

    Janusz Dudczyk

    2012-01-01

    Full Text Available Microstrip antenna has been recently one of the most innovative fields of antenna techniques. The main advantage of such an antenna is the simplicity of its production, little weight, a narrow profile, and easiness of integration of the radiating elements with the net of generators power systems. As a result of using arrays consisting of microstrip antennas; it is possible to decrease the size and weight and also to reduce the costs of components production as well as whole application systems. This paper presents possibilities of using artificial neural networks (ANNs in the process of forming a beam from radiating complex microstrip antenna. Algorithms which base on artificial neural networks use high parallelism of actions which results in considerable acceleration of the process of forming the antenna pattern. The appropriate selection of learning constants makes it possible to get theoretically a solution which will be close to the real time. This paper presents the training neural network algorithm with the selection of optimal network structure. The analysis above was made in case of following the emission source, setting to zero the pattern of direction of expecting interference, and following emission source compared with two constant interferences. Computer simulation was made in MATLAB environment on the basis of Flex Tool, a programme which creates artificial neural networks.

  20. Method of forming latent image to protect documents based on the effect moire

    OpenAIRE

    Troyan, О.

    2015-01-01

    Analysis of modern methods of information protection based on printed documents. It is shown that methods of protection from moiré effect provide reliable and effective protection by gaining new protection technology that is displayed in the optical acceleration motion layers and causes moire in fraud. Latent images can securely protect paper documents. Introduce a system of equations to calculate curvilinear patterns, where the optical formula of acceleration and periods moire stored in i...

  1. Materials interactions test methods to measure radionuclide release from waste forms under repository-relevant conditions

    International Nuclear Information System (INIS)

    Strickert, R.G.; Erikson, R.L.; Shade, J.W.

    1984-10-01

    At the request of the Basalt Waste Isolation Project, the Materials Characterization Center has collected and developed a set of procedures into a waste form compliance test method (MCC-14.4). The purpose of the test is to measure the steady-state concentrations of specified radionuclides in solutions contacting a waste form material. The test method uses a crushed waste form and basalt material suspended in a synthetic basalt groundwater and agitated for up to three months at 150 0 C under anoxic conditions. Elemental and radioisotopic analyses are made on filtered and unfiltered aliquots of the solution. Replicate experiments are performed and simultaneous tests are conducted with an approved test material (ATM) to help ensure precise and reliable data for the actual waste form material. Various features of the test method, equipment, and test conditions are reviewed. Experimental testing using actinide-doped borosilicate glasses are also discussed. 9 references, 2 tables

  2. Method for forming permanent magnets with different polarities for use in microelectromechanical devices

    Science.gov (United States)

    Roesler, Alexander W [Tijeras, NM; Christenson, Todd R [Albuquerque, NM

    2007-04-24

    Methods are provided for forming a plurality of permanent magnets with two different north-south magnetic pole alignments for use in microelectromechanical (MEM) devices. These methods are based on initially magnetizing the permanent magnets all in the same direction, and then utilizing a combination of heating and a magnetic field to switch the polarity of a portion of the permanent magnets while not switching the remaining permanent magnets. The permanent magnets, in some instances, can all have the same rare-earth composition (e.g. NdFeB) or can be formed of two different rare-earth materials (e.g. NdFeB and SmCo). The methods can be used to form a plurality of permanent magnets side-by-side on or within a substrate with an alternating polarity, or to form a two-dimensional array of permanent magnets in which the polarity of every other row of the array is alternated.

  3. Platinum catalyst formed on carbon nanotube by the in-liquid plasma method for fuel cell

    Energy Technology Data Exchange (ETDEWEB)

    Show, Yoshiyuki; Hirai, Akira; Almowarai, Anas; Ueno, Yutaro

    2015-12-01

    In-liquid plasma was generated in the carbon nanotube (CNT) dispersion fluid using platinum electrodes. The generated plasma spattered the surface of the platinum electrodes and dispersed platinum particles into the CNT dispersion. Therefore, the platinum nanoparticles were successfully formed on the CNT surface in the dispersion. The platinum nanoparticles were applied to the proton exchange membrane fuel cell (PEMFC) as a catalyst. The electrical power of 108 mW/cm{sup 2} was observed from the fuel cell which was assembled with the platinum catalyst formed on the CNT by the in-liquid plasma method. - Highlights: • The platinum catalyst was successfully formed on the CNT surface in the dispersion by the in-liquid plasma method. • The electrical power of 108 mW/cm{sup 2} was observed from the fuel cell which was assembled with the platinum catalyst formed on the CNT by the in-liquid plasma method.

  4. A New Pattern of Getting Nasty Number in Graphical Method

    Science.gov (United States)

    Sumathi, P.; Indhumathi, N.

    2018-04-01

    This paper proposed a new technique of getting nasty numbers using graphical method in linear programming problem and it has been proved for various Linear programming problems. And also some characterisation of nasty numbers is discussed in this paper.

  5. Different protein-protein interface patterns predicted by different machine learning methods.

    Science.gov (United States)

    Wang, Wei; Yang, Yongxiao; Yin, Jianxin; Gong, Xinqi

    2017-11-22

    Different types of protein-protein interactions make different protein-protein interface patterns. Different machine learning methods are suitable to deal with different types of data. Then, is it the same situation that different interface patterns are preferred for prediction by different machine learning methods? Here, four different machine learning methods were employed to predict protein-protein interface residue pairs on different interface patterns. The performances of the methods for different types of proteins are different, which suggest that different machine learning methods tend to predict different protein-protein interface patterns. We made use of ANOVA and variable selection to prove our result. Our proposed methods taking advantages of different single methods also got a good prediction result compared to single methods. In addition to the prediction of protein-protein interactions, this idea can be extended to other research areas such as protein structure prediction and design.

  6. Accelerated in-vitro release testing methods for extended-release parenteral dosage forms.

    Science.gov (United States)

    Shen, Jie; Burgess, Diane J

    2012-07-01

    This review highlights current methods and strategies for accelerated in-vitro drug release testing of extended-release parenteral dosage forms such as polymeric microparticulate systems, lipid microparticulate systems, in-situ depot-forming systems and implants. Extended-release parenteral dosage forms are typically designed to maintain the effective drug concentration over periods of weeks, months or even years. Consequently, 'real-time' in-vitro release tests for these dosage forms are often run over a long time period. Accelerated in-vitro release methods can provide rapid evaluation and therefore are desirable for quality control purposes. To this end, different accelerated in-vitro release methods using United States Pharmacopeia (USP) apparatus have been developed. Different mechanisms of accelerating drug release from extended-release parenteral dosage forms, along with the accelerated in-vitro release testing methods currently employed are discussed. Accelerated in-vitro release testing methods with good discriminatory ability are critical for quality control of extended-release parenteral products. Methods that can be used in the development of in-vitro-in-vivo correlation (IVIVC) are desirable; however, for complex parenteral products this may not always be achievable. © 2012 The Authors. JPP © 2012 Royal Pharmaceutical Society.

  7. Accelerated in vitro release testing methods for extended release parenteral dosage forms

    Science.gov (United States)

    Shen, Jie; Burgess, Diane J.

    2012-01-01

    Objectives This review highlights current methods and strategies for accelerated in vitro drug release testing of extended release parenteral dosage forms such as polymeric microparticulate systems, lipid microparticulate systems, in situ depot-forming systems, and implants. Key findings Extended release parenteral dosage forms are typically designed to maintain the effective drug concentration over periods of weeks, months or even years. Consequently, “real-time” in vitro release tests for these dosage forms are often run over a long time period. Accelerated in vitro release methods can provide rapid evaluation and therefore are desirable for quality control purposes. To this end, different accelerated in vitro release methods using United States Pharmacopoeia (USP) apparatus have been developed. Different mechanisms of accelerating drug release from extended release parenteral dosage forms, along with the accelerated in vitro release testing methods currently employed are discussed. Conclusions Accelerated in vitro release testing methods with good discriminatory ability are critical for quality control of extended release parenteral products. Methods that can be used in the development of in vitro-in vivo correlation (IVIVC) are desirable, however for complex parenteral products this may not always be achievable. PMID:22686344

  8. The preparation method of solid boron solution in silicon carbide in the form of micro powder

    International Nuclear Information System (INIS)

    Pampuch, R.; Stobierski, L.; Lis, J.; Bialoskorski, J.; Ermer, E.

    1993-01-01

    The preparation method of solid boron solution in silicon carbide in the form of micro power has been worked out. The method consists in introducing mixture of boron, carbon and silicon and heating in the atmosphere of inert gas to the 1573 K

  9. Method of forming a nanocluster comprising dielectric layer and device comprising such a layer

    NARCIS (Netherlands)

    2009-01-01

    A method of forming a dielectric layer (330) on a further layer (114, 320) of a semiconductor device (300) is disclosed. The method comprises depositing a dielectric precursor compound and a further precursor compound over the further layer (114, 320), the dielectric precursor compound comprising a

  10. Automated local line rolling forming and simplified deformation simulation method for complex curvature plate of ships

    Directory of Open Access Journals (Sweden)

    Y. Zhao

    2017-06-01

    Full Text Available Local line rolling forming is a common forming approach for the complex curvature plate of ships. However, the processing mode based on artificial experience is still applied at present, because it is difficult to integrally determine relational data for the forming shape, processing path, and process parameters used to drive automation equipment. Numerical simulation is currently the major approach for generating such complex relational data. Therefore, a highly precise and effective numerical computation method becomes crucial in the development of the automated local line rolling forming system for producing complex curvature plates used in ships. In this study, a three-dimensional elastoplastic finite element method was first employed to perform numerical computations for local line rolling forming, and the corresponding deformation and strain distribution features were acquired. In addition, according to the characteristics of strain distributions, a simplified deformation simulation method, based on the deformation obtained by applying strain was presented. Compared to the results of the three-dimensional elastoplastic finite element method, this simplified deformation simulation method was verified to provide high computational accuracy, and this could result in a substantial reduction in calculation time. Thus, the application of the simplified deformation simulation method was further explored in the case of multiple rolling loading paths. Moreover, it was also utilized to calculate the local line rolling forming for the typical complex curvature plate of ships. Research findings indicated that the simplified deformation simulation method was an effective tool for rapidly obtaining relationships between the forming shape, processing path, and process parameters.

  11. Development of an ellipse fitting method with which to analyse selected area electron diffraction patterns

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, D.R.G., E-mail: dmitchel@uow.edu.au [Electron Microscopy Centre, Australian Institute for Innovative Materials, Innovation Campus, University of Wollongong, North Wollongong, NSW 2500 (Australia); Van den Berg, J.A. [Electron Microscopy Centre, Australian Institute for Innovative Materials, Innovation Campus, University of Wollongong, North Wollongong, NSW 2500 (Australia); Catalyst Fundamentals, Fischer-Tropsch and Syngas Conversion Research, Sasol Technology R & D, Sasolburg 1947 (South Africa)

    2016-01-15

    A software method has been developed which uses ellipse fitting to analyse electron diffraction patterns from polycrystalline materials. The method, which requires minimal user input, can determine the pattern centre and the diameter of diffraction rings with sub-pixel precision. This enables accurate crystallographic information to be obtained in a rapid and consistent manner. Since the method fits ellipses, it can detect, quantify and correct any elliptical distortion introduced by the imaging system. Distortion information derived from polycrystalline patterns as a function of camera length can be subsequently recalled and applied to single crystal patterns, resulting in improved precision and accuracy. The method has been implemented as a plugin for the DigitalMicrograph software by Gatan, and is a freely available via the internet. - Highlights: • A robust ellipse fitting method is developed. • Freely available software for automated diffraction pattern analysis is demonstrated. • Measurement and correction of elliptical distortion is routinely achieved.

  12. PWM pulse pattern optimization method using carrier frequency modulation. Carrier shuhasu hencho ni yoru PWM pulse pattern saitekikaho

    Energy Technology Data Exchange (ETDEWEB)

    Iwaji, Y.; Fukuda, S. (Hokkaido University, Sapporo (Japan))

    1991-07-15

    Sinusoidal inverters are getting more widely used keeping pace with the development of semiconductor switching elements. This paper discusses optimizing a PWM pulse pattern at an inverter output to drive an induction motor, proposes methods for improving distortion and torque ripples using a carrier frequency modulation (CFM), and describes a method for realizing the improvement through use of a single-chip microcomputer. The method defines evaluation parameters corresponding to the distortion and torque ripples, and optimizes the CFM depth to the parameters. The PWM pulse pattern has its voltage vector and time width so selected that the time integrated space vector of a three-phase voltage approaches a circular locus. Furthermore, the carrier frequency, that is the sampling frequency of the inverter, is also adjusted so that the above evaluation parameters are minimized. The addition of a new variable called the frequency modulation provides freedom in selecting an output characteristic as called for by the purpose. 12 refs., 18 figs.

  13. Simulation of crystalline pattern formation by the MPFC method

    Directory of Open Access Journals (Sweden)

    Starodumov Ilya

    2017-01-01

    Full Text Available The Phase Field Crystal model in hyperbolic formulation (modified PFC or MPFC, is investigated as one of the most promising techniques for modeling the formation of crystal patterns. MPFC is a convenient and fundamentally based description linking nano-and meso-scale processes in the evolution of crystal structures. The presented model is a powerful tool for mathematical modeling of the various operations in manufacturing. Among them is the definition of process conditions for the production of metal castings with predetermined properties, the prediction of defects in the crystal structure during casting, the evaluation of quality of special coatings, and others. Our paper presents the structure diagram which was calculated for the one-mode MPFC model and compared to the results of numerical simulation for the fast phase transitions. The diagram is verified by the numerical simulation and also strongly correlates to the previously calculated diagrams. The computations have been performed using software based on the effective parallel computational algorithm.

  14. Planting pattern and weed control method influence on yield production of corn (Zea mays L.)

    Science.gov (United States)

    Purba, E.; Nasution, D. P.

    2018-02-01

    Field experiment was carried out to evaluate the influence of planting patterns and weed control methods on the growth and yield of corn. The effect of the planting pattern and weed control method was studied in a split plot design. The main plots were that of planting pattern single row (25cm x 60cm), double row (25cm x 25cm x 60cm) and triangle row ( 25cm x 25cm x 25cm). Subplot was that of weed control method consisted five methods namely weed free throughout the growing season, hand weeding, sprayed with glyphosate, sprayed with paraquat, and no weeding.. Result showed that both planting pattern and weed control method did not affect the growth of corn. However, planting pattern and weed control method significantly affected yield production. Yield resulted from double row and triangle planting pattern was 14% and 41% higher, consecutively, than that of single row pattern. The triangle planting pattern combined with any weed control method produced the highest yield production of corn.

  15. Properties of made by different methods of RP impeller foundry patterns

    Directory of Open Access Journals (Sweden)

    G. Budzik

    2007-04-01

    Full Text Available This article presents the tests of properties of foundry patterns of turbocharger turbine impeller. Impellers prototypes were predestinated for casting by method losing patterns. There were carried out tests of these prototypes made by different methods of Rapid Prototyping (RP. Two impeller were made by growth methods: stereolitography (SLA and three dimensional printing (3DP. One prototype was made by the method of Vacuum Casting as a wax casting. Tests were executed in the Department of Machine Design of Rzeszow University of Technology in cooperation with WSK PZL Rzeszow and Car Technology Krakow. First impeller was carried out by method of stereolitography on SLA 250 plant. That pattern was also used to carry out silicon matrix for casting of wax pattern. Next pattern was printed by three dimensional printer Z510 from the powder ZP14. Good removability of the pattern from the mould is particularly essential for impellers of small turbines with blades of small thickness of their section. All pattern were tested on their removability from the ceramic mould. The best melting properties had the wax pattern. Patterns made from resin SL5170 (SLA and powder ZP14 (3DP were removed in the process of burning but about 1% of soot was left in the mould.

  16. Radioactive tracer method as an instrument for testing effectiveness of effluent treatment installations and mixing patterns in natural streams

    Energy Technology Data Exchange (ETDEWEB)

    Szpilowski, S; Strzelczak, G; Winnicki, R [Institute of Nuclear Research, Warsaw (Poland)

    1976-01-01

    The radiotracer methods of evaluation of sewage flow rate, testing of effluent treatment plants and mixing patterns in natural streams have been described. Experimental works were carried out for industrial installations and natural streams. As a tracer of liquid phase an aqueous KBr solution labelled with /sup 82/Br have been used. The sediment materials have been labelled with /sup 198/Au in the form of colloidal gold. The results of investigations have been utilized for treatment process analysis and water pollution control.

  17. AN UNUSUAL PATTERN OF GENE FLOW BETWEEN THE TWO SOCIAL FORMS OF THE FIRE ANT SOLENOPSIS INVICTA.

    Science.gov (United States)

    Ross, Kenneth G; Shoemaker, D DeWayne

    1993-10-01

    Uncertainty over the role of shifts in social behavior in the process of speciation in social insects has stimulated interest in determining the extent of gene flow between conspecific populations differing in colony social organization. Allele and genotype frequencies at 12 neutral polymorphic protein markers, as well as the numbers of alleles at the sex-determining locus (loci), are shown here to be consistent with significant ongoing gene flow between two geographically adjacent populations of Solenopsis invicta that differ in colony queen number. Data from a thirteenth protein marker that is under strong differential selection in the two social forms confirm that such gene flow occurs. Data from this selected locus, combined with knowledge of the reproductive biology of the two social forms, further suggest that interform gene flow is largely unidirectional and mediated through males only. This unusual pattern of gene flow results from the influence of the unique social enviroments of the two forms on the behavior of workers and on the reproductive physiology of sexuals. © 1993 The Society for the Study of Evolution.

  18. Crystallization from microemulsions ? a novel method for the preparation of new crystal forms of aspartame

    Science.gov (United States)

    Füredi-Milhofer, Helga; Garti, N.; Kamyshny, A.

    1999-03-01

    Solubilization and crystallization of the artificial sweetener aspartame (APM), in water/isooctane microemulsions stabilized with sodium diisooctyl sulfosuccinate (AOT) has been investigated. The amount of aspartame that could be solubilized depended primarily on the amount of surfactant and on the temperature. The maximum AOT/aspartame molar ratio at the w/o interface is shown to be 6.2 at 25°C. It was concluded that the dipeptide is located at the w/o interface interspersed between surfactant molecules and that it acts as a cosurfactant. A new crystal form, APM III, was obtained by cooling of hot w/isooctane/AOT microemulsions containing solubilized aspartame. The new crystal form exhibits a distinct X-ray diffraction powder pattern, as well as changes in the FTIR spectra, thermogravimetric and DSC patterns. H-NMR spectra of APM III dissolved in D 2O were identical to the spectrum of commercial aspartame recorded under the same conditions. The new crystal form has greatly improved dissolution kinetics.

  19. Fraud adversely affecting the budget of the Europen Union: the forms, methods and causes

    Directory of Open Access Journals (Sweden)

    Zlata Đurđević

    2006-09-01

    Full Text Available The paper analyses the forms, methods and causes of fraud that are perpetrated to the detriment of the budget of the European Union. The forms in which EU fraud appears are shown according to the criterion of kind of budgetary resource. Crime affecting the budgetary revenue of the EU tends to appear in the form of customs duty-evasion and false declarations concerning the customs-relevant information about goods. Crime adversely affecting the expenditure side of the EU budget appears in the form of subsidy fraud in the area of the Common Agricultural Policy, and subsidy fraud in the area of the structural policies. The methods used for the EU fraud committed and considered in the paper are document forgery, concealment of goods, corruption, violence and fictional business and evasion of the laws. In conclusion an explanation is given of the main exogenous criminogenic factors that lead to the EU frauds commonly perpetrated.

  20. Structural pattern recognition methods based on string comparison for fusion databases

    International Nuclear Information System (INIS)

    Dormido-Canto, S.; Farias, G.; Dormido, R.; Vega, J.; Sanchez, J.; Duro, N.; Vargas, H.; Ratta, G.; Pereira, A.; Portas, A.

    2008-01-01

    Databases for fusion experiments are designed to store several million waveforms. Temporal evolution signals show the same patterns under the same plasma conditions and, therefore, pattern recognition techniques allow the identification of similar plasma behaviours. This article is focused on the comparison of structural pattern recognition methods. A pattern can be composed of simpler sub-patterns, where the most elementary sub-patterns are known as primitives. Selection of primitives is an essential issue in structural pattern recognition methods, because they determine what types of structural components can be constructed. However, it should be noted that there is not a general solution to extract structural features (primitives) from data. So, four different ways to compute the primitives of plasma waveforms are compared: (1) constant length primitives, (2) adaptive length primitives, (3) concavity method and (4) concavity method for noisy signals. Each method defines a code alphabet and, in this way, the pattern recognition problem is carried out via string comparisons. Results of the four methods with the TJ-II stellarator databases will be discussed

  1. Structural pattern recognition methods based on string comparison for fusion databases

    Energy Technology Data Exchange (ETDEWEB)

    Dormido-Canto, S. [Dpto. Informatica y Automatica - UNED 28040, Madrid (Spain)], E-mail: sebas@dia.uned.es; Farias, G.; Dormido, R. [Dpto. Informatica y Automatica - UNED 28040, Madrid (Spain); Vega, J. [Asociacion EURATOM/CIEMAT para Fusion, 28040, Madrid (Spain); Sanchez, J.; Duro, N.; Vargas, H. [Dpto. Informatica y Automatica - UNED 28040, Madrid (Spain); Ratta, G.; Pereira, A.; Portas, A. [Asociacion EURATOM/CIEMAT para Fusion, 28040, Madrid (Spain)

    2008-04-15

    Databases for fusion experiments are designed to store several million waveforms. Temporal evolution signals show the same patterns under the same plasma conditions and, therefore, pattern recognition techniques allow the identification of similar plasma behaviours. This article is focused on the comparison of structural pattern recognition methods. A pattern can be composed of simpler sub-patterns, where the most elementary sub-patterns are known as primitives. Selection of primitives is an essential issue in structural pattern recognition methods, because they determine what types of structural components can be constructed. However, it should be noted that there is not a general solution to extract structural features (primitives) from data. So, four different ways to compute the primitives of plasma waveforms are compared: (1) constant length primitives, (2) adaptive length primitives, (3) concavity method and (4) concavity method for noisy signals. Each method defines a code alphabet and, in this way, the pattern recognition problem is carried out via string comparisons. Results of the four methods with the TJ-II stellarator databases will be discussed.

  2. Method of forming components for a high-temperature secondary electrochemical cell

    Science.gov (United States)

    Mrazek, Franklin C.; Battles, James E.

    1983-01-01

    A method of forming a component for a high-temperature secondary electrochemical cell having a positive electrode including a sulfide selected from the group consisting of iron sulfides, nickel sulfides, copper sulfides and cobalt sulfides, a negative electrode including an alloy of aluminum and an electrically insulating porous separator between said electrodes. The improvement comprises forming a slurry of solid particles dispersed in a liquid electrolyte such as the lithium chloride-potassium chloride eutetic, casting the slurry into a form having the shape of one of the components and smoothing the exposed surface of the slurry, cooling the cast slurry to form the solid component, and removing same. Electrodes and separators can be thus formed.

  3. INNOVATIVE FORMS SUPPORTING SAFE METHODS OF WORK IN SAFETY ENGINEERING FOR THE DEVELOPMENT OF INTELLIGENT SPECIALIZATIONS

    Directory of Open Access Journals (Sweden)

    Anna GEMBALSKA-KWIECIEŃ

    2016-10-01

    Full Text Available The article discusses innovative forms of participation of employees in the work safety system. It also presents the advantages of these forms of employees’ involvement. The aim of empirical studies was the analysis of their behavior and attitude towards health and safety at work. The issues considered in the article have a significant impact on the improvement of methods of prevention related to work safety and aided the creation of a healthy society.

  4. Analysis of a renormalization group method and normal form theory for perturbed ordinary differential equations

    Science.gov (United States)

    DeVille, R. E. Lee; Harkin, Anthony; Holzer, Matt; Josić, Krešimir; Kaper, Tasso J.

    2008-06-01

    For singular perturbation problems, the renormalization group (RG) method of Chen, Goldenfeld, and Oono [Phys. Rev. E. 49 (1994) 4502-4511] has been shown to be an effective general approach for deriving reduced or amplitude equations that govern the long time dynamics of the system. It has been applied to a variety of problems traditionally analyzed using disparate methods, including the method of multiple scales, boundary layer theory, the WKBJ method, the Poincaré-Lindstedt method, the method of averaging, and others. In this article, we show how the RG method may be used to generate normal forms for large classes of ordinary differential equations. First, we apply the RG method to systems with autonomous perturbations, and we show that the reduced or amplitude equations generated by the RG method are equivalent to the classical Poincaré-Birkhoff normal forms for these systems up to and including terms of O(ɛ2), where ɛ is the perturbation parameter. This analysis establishes our approach and generalizes to higher order. Second, we apply the RG method to systems with nonautonomous perturbations, and we show that the reduced or amplitude equations so generated constitute time-asymptotic normal forms, which are based on KBM averages. Moreover, for both classes of problems, we show that the main coordinate changes are equivalent, up to translations between the spaces in which they are defined. In this manner, our results show that the RG method offers a new approach for deriving normal forms for nonautonomous systems, and it offers advantages since one can typically more readily identify resonant terms from naive perturbation expansions than from the nonautonomous vector fields themselves. Finally, we establish how well the solution to the RG equations approximates the solution of the original equations on time scales of O(1/ɛ).

  5. Optimization and validation of spectrophotometric methods for determination of finasteride in dosage and biological forms

    Science.gov (United States)

    Amin, Alaa S.; Kassem, Mohammed A.

    2012-01-01

    Aim and Background: Three simple, accurate and sensitive spectrophotometric methods for the determination of finasteride in pure, dosage and biological forms, and in the presence of its oxidative degradates were developed. Materials and Methods: These methods are indirect, involve the addition of excess oxidant potassium permanganate for method A; cerric sulfate [Ce(SO4)2] for methods B; and N-bromosuccinimide (NBS) for method C of known concentration in acid medium to finasteride, and the determination of the unreacted oxidant by measurement of the decrease in absorbance of methylene blue for method A, chromotrope 2R for method B, and amaranth for method C at a suitable maximum wavelength, λmax: 663, 528, and 520 nm, for the three methods, respectively. The reaction conditions for each method were optimized. Results: Regression analysis of the Beer plots showed good correlation in the concentration ranges of 0.12–3.84 μg mL–1 for method A, and 0.12–3.28 μg mL–1 for method B and 0.14 – 3.56 μg mL–1 for method C. The apparent molar absorptivity, Sandell sensitivity, detection and quantification limits were evaluated. The stoichiometric ratio between the finasteride and the oxidant was estimated. The validity of the proposed methods was tested by analyzing dosage forms and biological samples containing finasteride with relative standard deviation ≤ 0.95. Conclusion: The proposed methods could successfully determine the studied drug with varying excess of its oxidative degradation products, with recovery between 99.0 and 101.4, 99.2 and 101.6, and 99.6 and 101.0% for methods A, B, and C, respectively. PMID:23781478

  6. Standard test method for splitting tensile strength for brittle nuclear waste forms

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    1989-01-01

    1.1 This test method is used to measure the static splitting tensile strength of cylindrical specimens of brittle nuclear waste forms. It provides splitting tensile-strength data that can be used to compare the strength of waste forms when tests are done on one size of specimen. 1.2 The test method is applicable to glass, ceramic, and concrete waste forms that are sufficiently homogeneous (Note 1) but not to coated-particle, metal-matrix, bituminous, or plastic waste forms, or concretes with large-scale heterogeneities. Cementitious waste forms with heterogeneities >1 to 2 mm and 5 mm can be tested using this procedure provided the specimen size is increased from the reference size of 12.7 mm diameter by 6 mm length, to 51 mm diameter by 100 mm length, as recommended in Test Method C 496 and Practice C 192. Note 1—Generally, the specimen structural or microstructural heterogeneities must be less than about one-tenth the diameter of the specimen. 1.3 This test method can be used as a quality control chec...

  7. DNA methylation patterns of genes related to immune response in the different clinical forms of oral lichen planus.

    Science.gov (United States)

    Cruz, Aline Fernanda; de Resende, Renata Gonçalves; de Lacerda, Júlio César Tanos; Pereira, Núbia Braga; Melo, Leonardo Augusto; Diniz, Marina Gonçalves; Gomes, Carolina Cavalieri; Gomez, Ricardo Santiago

    2018-01-01

    The oral lichen planus is a chronic inflammatory disease. Although its aetiology is not well understood, the role of T lymphocytes in its inflammatory events is recognised. Identifying the epigenetic mechanisms involved in the pathogenesis of this immune-mediated condition is fundamental for understanding the inflammatory reaction that occurs in the disease. The purpose of this work was to evaluate the methylation pattern of 21 immune response-related genes in the different clinical forms of oral lichen planus. A cross-sectional study was performed to analyse the DNA methylation patterns in three distinct groups of oral lichen planus: (i) reticular/plaque lesions; (ii) erosive lesions; (iii) normal oral mucosa (control group). After DNA extraction from biopsies, the samples were submitted to digestions by methylation-sensitive and methylation-dependent enzymes and double digestion. The relative percentage of methylated DNA for each gene was provided using real-time polymerase chain reaction arrays. Hypermethylation of the STAT5A gene was observed only in the control group (59.0%). A higher hypermethylation of the ELANE gene was found in reticular/plaque lesions (72.1%) compared to the erosive lesions (50.0%). Our results show variations in the methylation profile of immune response-related genes, according to the clinical type of oral lichen planus after comparing with the normal oral mucosa. Further studies are necessary to validate these findings using gene expression analysis. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  8. Derivative spectrophotometric method for simultaneous determination of clindamycin phosphate and tretinoin in pharmaceutical dosage forms.

    Science.gov (United States)

    Barazandeh Tehrani, Maliheh; Namadchian, Melika; Fadaye Vatan, Sedigheh; Souri, Effat

    2013-04-10

    A derivative spectrophotometric method was proposed for the simultaneous determination of clindamycin and tretinoin in pharmaceutical dosage forms. The measurement was achieved using the first and second derivative signals of clindamycin at (1D) 251 nm and (2D) 239 nm and tretinoin at (1D) 364 nm and (2D) 387 nm.The proposed method showed excellent linearity at both first and second derivative order in the range of 60-1200 and 1.25-25 μg/ml for clindamycin phosphate and tretinoin respectively. The within-day and between-day precision and accuracy was in acceptable range (CVpharmaceutical dosage form.

  9. Rapid fabrication of an ordered nano-dot array by the combination of nano-plastic forming and annealing methods

    International Nuclear Information System (INIS)

    Yoshino, Masahiko; Ohsawa, Hiroki; Yamanaka, Akinori

    2011-01-01

    In this paper, a new fabrication method for an ordered nano-dot array is developed. Combination of coating, nano-plastic forming and annealing processes is studied to produce uniformly sized and ordered gold nano-dot array on a quartz glass substrate. The experimental results reveal that patterning of a groove grid on the gold-coated substrate with NPF is effective to obtain the ordered gold nano-dot array. In the proposed fabrication process, the size of the gold nano-dot can be controlled by adjusting the groove grid size. A minimum gold nano-dot array fabricated on a quartz-glass substrate was 93 nm in diameter and 100 nm in pitch. Furthermore, the mechanism of nano-dot array generation by the presented process is investigated. Using a theoretical model it is revealed that the proposed method is capable of fabrication of smaller nano-dots than 10 nm by controlling process conditions adequately.

  10. A Kinematic Method for Footstrike Pattern Detection in Barefoot and Shod Runners

    OpenAIRE

    Altman, Allison R.; Davis, Irene S.

    2011-01-01

    Footstrike patterns during running can be classified discretely into a rearfoot strike, midfoot strike and forefoot strike by visual observation. However, the footstrike pattern can also be classified on a continuum, ranging from 0–100% (extreme rearfoot to extreme forefoot) using the strike index, a measure requiring force plate data. When force data are not available, an alternative method to quantify the strike pattern must be used. The purpose of this paper was to quantify the continuum o...

  11. SYNTHESIS METHODS OF ALGEBRAIC NORMAL FORM OF MANY-VALUED LOGIC FUNCTIONS

    Directory of Open Access Journals (Sweden)

    A. V. Sokolov

    2016-01-01

    Full Text Available The rapid development of methods of error-correcting coding, cryptography, and signal synthesis theory based on the principles of many-valued logic determines the need for a more detailed study of the forms of representation of functions of many-valued logic. In particular the algebraic normal form of Boolean functions, also known as Zhegalkin polynomial, that well describe many of the cryptographic properties of Boolean functions is widely used. In this article, we formalized the notion of algebraic normal form for many-valued logic functions. We developed a fast method of synthesis of algebraic normal form of 3-functions and 5-functions that work similarly to the Reed-Muller transform for Boolean functions: on the basis of recurrently synthesized transform matrices. We propose the hypothesis, which determines the rules of the synthesis of these matrices for the transformation from the truth table to the coefficients of the algebraic normal form and the inverse transform for any given number of variables of 3-functions or 5-functions. The article also introduces the definition of algebraic degree of nonlinearity of the functions of many-valued logic and the S-box, based on the principles of many-valued logic. Thus, the methods of synthesis of algebraic normal form of 3-functions applied to the known construction of recurrent synthesis of S-boxes of length N = 3k, whereby their algebraic degrees of nonlinearity are computed. The results could be the basis for further theoretical research and practical applications such as: the development of new cryptographic primitives, error-correcting codes, algorithms of data compression, signal structures, and algorithms of block and stream encryption, all based on the perspective principles of many-valued logic. In addition, the fast method of synthesis of algebraic normal form of many-valued logic functions is the basis for their software and hardware implementation.

  12. Indomethacin nanocrystals prepared by different laboratory scale methods: effect on crystalline form and dissolution behavior

    Energy Technology Data Exchange (ETDEWEB)

    Martena, Valentina; Censi, Roberta [University of Camerino, School of Pharmacy (Italy); Hoti, Ela; Malaj, Ledjan [University of Tirana, Department of Pharmacy (Albania); Di Martino, Piera, E-mail: piera.dimartino@unicam.it [University of Camerino, School of Pharmacy (Italy)

    2012-12-15

    The objective of this study is to select very simple and well-known laboratory scale methods able to reduce particle size of indomethacin until the nanometric scale. The effect on the crystalline form and the dissolution behavior of the different samples was deliberately evaluated in absence of any surfactants as stabilizers. Nanocrystals of indomethacin (native crystals are in the {gamma} form) (IDM) were obtained by three laboratory scale methods: A (Batch A: crystallization by solvent evaporation in a nano-spray dryer), B (Batch B-15 and B-30: wet milling and lyophilization), and C (Batch C-20-N and C-40-N: Cryo-milling in the presence of liquid nitrogen). Nanocrystals obtained by the method A (Batch A) crystallized into a mixture of {alpha} and {gamma} polymorphic forms. IDM obtained by the two other methods remained in the {gamma} form and a different attitude to the crystallinity decrease were observed, with a more considerable decrease in crystalline degree for IDM milled for 40 min in the presence of liquid nitrogen. The intrinsic dissolution rate (IDR) revealed a higher dissolution rate for Batches A and C-40-N, due to the higher IDR of {alpha} form than {gamma} form for the Batch A, and the lower crystallinity degree for both the Batches A and C-40-N. These factors, as well as the decrease in particle size, influenced the IDM dissolution rate from the particle samples. Modifications in the solid physical state that may occur using different particle size reduction treatments have to be taken into consideration during the scale up and industrial development of new solid dosage forms.

  13. Cliché fabrication method using precise roll printing process with 5 um pattern width

    Science.gov (United States)

    Shin, Yejin; Kim, Inyoung; Oh, Dong-Ho; Lee, Taik-Min

    2016-09-01

    Among the printing processes for printed electronic devices, gravure offset and reverse offset method have drawn attention for its fine pattern printing possibility. These printing methods use cliché, which has critical effect on the final product precision and quality. In this research, a novel precise cliché replica method is proposed. It consists of copper sputtering, precise mask pattern printing with 5 um width using reverse offset printing, Ni electroplating, lift-off, etching, and DLC coating. We finally compare the fabricated replica cliché with the original one and print out precise patterns using the replica cliché.

  14. Novel Compound-Forming Technology Using Bioprinting and Electrospinning for Patterning a 3D Scaffold Construct with Multiscale Channels

    Directory of Open Access Journals (Sweden)

    Yuanshao Sun

    2016-12-01

    Full Text Available One of the biggest challenges for tissue engineering is to efficiently provide oxygen and nutrients to cells on a three-dimensional (3D engineered scaffold structure. Thus, achieving sufficient vascularization of the structure is a critical problem in tissue engineering. This facilitates the need to develop novel methods to enhance vascularization. Use of patterned hydrogel structures with multiscale channels can be used to achieve the required vascularization. Patterned structures need to be biocompatible and biodegradable. In this study, gelatin was used as the main part of a hydrogel to prepare a biological structure with 3D multiscale channels using bioprinting combined with selection of suitable materials and electrostatic spinning. Human umbilical vein endothelial cells (HUVECs were then used to confirm efficacy of the structure, inferred from cell viability on different engineered construct designs. HUVECs were seeded on the surface of channels and cultured in vitro. HUVECs showed high viability and diffusion within the construct. This method can be used as a practical platform for the fabrication of engineered construct for vascularization.

  15. Classical reconstruction of interference patterns of position-wave-vector-entangled photon pairs by the time-reversal method

    Science.gov (United States)

    Ogawa, Kazuhisa; Kobayashi, Hirokazu; Tomita, Akihisa

    2018-02-01

    The quantum interference of entangled photons forms a key phenomenon underlying various quantum-optical technologies. It is known that the quantum interference patterns of entangled photon pairs can be reconstructed classically by the time-reversal method; however, the time-reversal method has been applied only to time-frequency-entangled two-photon systems in previous experiments. Here, we apply the time-reversal method to the position-wave-vector-entangled two-photon systems: the two-photon Young interferometer and the two-photon beam focusing system. We experimentally demonstrate that the time-reversed systems classically reconstruct the same interference patterns as the position-wave-vector-entangled two-photon systems.

  16. New spectrofluorimetric method for the determination of nizatidine in bulk form and in pharmaceutical preparations

    Science.gov (United States)

    Karasakal, Ayça; Ulu, Sevgi Tatar

    2013-08-01

    A simple, accurate and highly sensitive spectrofluorimetric method has been developed for determination of nizatidine in pure form and in pharmaceutical dosage forms. The method is based on the reaction between nizatidine and 1-dimethylaminonaphthalene-5-sulphonyl chloride in carbonate buffer, pH 10.5, to yield a highly fluorescent derivative peaking at 513 nm after excitation at 367 nm. Various factors affecting the fluorescence intensity of nizatidin-dansyl derivative were studied and conditions were optimized. The method was validated as per ICH guidelines. The fluorescence concentration plot was rectilinear over the range of 25-300 ng/mL. Limit of detection and limit of quantification were calculated as 11.71 and 35.73 ng/mL, respectively. The proposed method was successfully applied to pharmaceutical preparations.

  17. MODEL OF METHODS OF FORMING BIOLOGICAL PICTURE OF THE WORLD OF SECONDARY SCHOOL PUPILS

    Directory of Open Access Journals (Sweden)

    Mikhail A. Yakunchev

    2016-12-01

    Full Text Available Introduction: the problem of development of a model of methods of forming the biological picture of the world of pupils as a multicomponent and integrative expression of the complete educational process is considered in the article. It is stated that the results of the study have theoretical and practical importance for effective subject preparation of senior pupils based on acquiring of systematic and generalized knowledge about wildlife. The correspondence of the main idea of the article to the scientific profile of the journal “Integration of Education” determines the choice of the periodical for publication. Materials and Methods: the results of the analysis of materials on modeling of the educational process, on specific models of the formation of a complete comprehension of the scientific picture of the world and its biological component make it possible to suggest a lack of elaboration of the aspect of pedagogical research under study. Therefore, the search for methods to overcome these gaps and to substantiate a particular model, relevant for its practical application by a teacher, is important. The study was based on the use of methods of theoretical level, including the analysis of pedagogical and methodological literature, modeling and generalized expression of the model of forming the biological picture of the world of secondary school senior pupils, which were of higher priority. Results: the use of models of organization of subject preparation of secondary school pupils takes a priority position, as they help to achieve the desired results of training, education and development. The model of methods of forming a biological picture of the world is represented as a theoretical construct in the unity of objective, substantive, procedural, diagnostic and effective blocks. Discussion and Conclusions: in a generalized form the article expresses the model of methods of forming the biological picture of the world of secondary school

  18. A new general method for transform canonically a Hamiltonian in another one of a given form

    International Nuclear Information System (INIS)

    Gomez T, A.

    2002-01-01

    The more general method to perform a canonical transformation of a Hamiltonian into another one of a given form is based on the repeated use of the Hamilton-Jacobi equation. This is usually a tedious technique which leads to some particular solutions of the problem. We present a new general method which does not rely on the Hamilton-Jacobi equation and moreover it gives all the possible solutions. (Author)

  19. Theories, Methods and Numerical Technology of Sheet Metal Cold and Hot Forming Analysis, Simulation and Engineering Applications

    CERN Document Server

    Hu, Ping; Liu, Li-zhong; Zhu, Yi-guo

    2013-01-01

    Over the last 15 years, the application of innovative steel concepts in the automotive industry has increased steadily. Numerical simulation technology of hot forming of high-strength steel allows engineers to modify the formability of hot forming steel metals and to optimize die design schemes. Theories, Methods and Numerical Technology of Sheet Metal Cold and Hot Forming focuses on hot and cold forming theories, numerical methods, relative simulation and experiment techniques for high-strength steel forming and die design in the automobile industry. Theories, Methods and Numerical Technology of Sheet Metal Cold and Hot Forming introduces the general theories of cold forming, then expands upon advanced hot forming theories and simulation methods, including: • the forming process, • constitutive equations, • hot boundary constraint treatment, and • hot forming equipment and experiments. Various calculation methods of cold and hot forming, based on the authors’ experience in commercial CAE software f...

  20. Method of forming a ceramic superconducting composite wire using a molten pool

    International Nuclear Information System (INIS)

    Geballe, T.H.; Feigelson, R.S.; Gazit, D.

    1991-01-01

    This paper describes a method for making a flexible superconductive composite wire. It comprises: drawing a wire of noble metal through a molten material, formed by melting a solid formed by pressing powdered Bi 2 O 3 , CaCO 3 SrCO 3 and CuO in a ratio of components necessary for forming a Bi-Sr-Ca-Cu-O superconductor, into the solid and sintering at a temperature in the range of 750 degrees - 800 degrees C. for 10-20 hours, whereby the wire is coated by the molten material; and cooling the coated wire to solidify the molten material to form the superconductive flexible composite wire without need of further annealing

  1. Future of the Learning Activities in Teenage School: Content, Methods, and Forms

    Directory of Open Access Journals (Sweden)

    Vorontsov A.B.

    2015-11-01

    Full Text Available the early 1990s their scientific research results have been formed in the educational system and began to be used in general primary school. However, when the widespread use of developmental education in elementary school, further studies on the age possibilities of adolescents and the content of their education have not been completed. Targeted research was organized again under the leadership of B.D. Elkonin only in 2000. Designing of teenage school in the framework of the principles and ideology of this system started at the same time at the Psychological Institute of the Russian Academy of Education and many other educational institutions. The article presents the hypothetical ideas about the content, forms and methods of organization of educational process in the second stage of schooling. Particular attention is paid to the fate of the educational activity in teenage school, as well as methods and forms of organization of other activities in the adolescent school.

  2. Interaction between droplets in a ternary microemulsion evaluated by the relative form factor method

    International Nuclear Information System (INIS)

    Nagao, Michihiro; Seto, Hideki; Yamada, Norifumi L.

    2007-01-01

    This paper describes the concentration dependence of the interaction between water droplets coated by a surfactant monolayer using the contrast variation small-angle neutron scattering technique. In the first part, we explain the idea of how to extract a relatively model free structure factor from the scattering data, which is called the relative form factor method. In the second part, the experimental results for the shape of the droplets (form factor) are described. In the third part the relatively model free structure factor is shown, and finally the concentration dependence of the interaction potential between droplets is discussed. The result indicates the validity of the relative form factor method, and the importance of the estimation of the model free structure factor to discuss the nature of structure formation in microemulsion systems

  3. Optimization of instruction and training process through content, form and methods

    International Nuclear Information System (INIS)

    Rozinek, P.

    1983-01-01

    The content orientation and development of forms and methods of nuclear power plant personnel training are described. The subject matter content consisted of two units: group and professional. Professional was divided into specialized sub-units: the primary circuit part, secondary circuit part, electric, chemistry, dosimetry. The system of final examinations is described. (J.P.)

  4. Method for forming nuclear fuel containers of a composite construction and the product thereof

    International Nuclear Information System (INIS)

    Cheng, B.-C.; Rosenbaum, H.S.; Armijo, J.S.

    1981-01-01

    An improved method of producing a composite nuclear fuel container is described which comprises a casing or fuel sheath of zirconium or its alloy with a lining cladding of deposited copper superimposed over the inside surface of the zirconium or alloy and a layer of oxide of the zirconium or alloy formed on the inside surface of the casing or sheath. (U.K.)

  5. Catalyst support structure, catalyst including the structure, reactor including a catalyst, and methods of forming same

    Science.gov (United States)

    Van Norman, Staci A.; Aston, Victoria J.; Weimer, Alan W.

    2017-05-09

    Structures, catalysts, and reactors suitable for use for a variety of applications, including gas-to-liquid and coal-to-liquid processes and methods of forming the structures, catalysts, and reactors are disclosed. The catalyst material can be deposited onto an inner wall of a microtubular reactor and/or onto porous tungsten support structures using atomic layer deposition techniques.

  6. A numerical method for the design of free-form reflectors for lighting applications

    NARCIS (Netherlands)

    Prins, C.R.; Thije Boonkkamp, ten J.H.M.; Roosmalen, van J.; IJzerman, W.L.; Tukker, T.W.

    2013-01-01

    In this article we present a method for the design of fully free-form reflectors for illumination systems. We derive an elliptic partial differential equation of the Monge-Ampère type for the surface of a reflector that converts an arbitrary parallel beam of light into a desired intensity output

  7. AN ELECTROPLATING METHOD OF FORMING PLATINGS OF NICKEL, COBALT, NICKEL ALLOYS OR COBALT ALLOYS

    DEFF Research Database (Denmark)

    1997-01-01

    An electroplating method of forming platings of nickel, cobalt, nickel alloys or cobalt alloys with reduced stresses in an electrodepositing bath of the type: Watt's bath, chloride bath or a combination thereof, by employing pulse plating with periodic reverse pulse and a sulfonated naphthalene...

  8. Creating IRT-Based Parallel Test Forms Using the Genetic Algorithm Method

    Science.gov (United States)

    Sun, Koun-Tem; Chen, Yu-Jen; Tsai, Shu-Yen; Cheng, Chien-Fen

    2008-01-01

    In educational measurement, the construction of parallel test forms is often a combinatorial optimization problem that involves the time-consuming selection of items to construct tests having approximately the same test information functions (TIFs) and constraints. This article proposes a novel method, genetic algorithm (GA), to construct parallel…

  9. Generalization of opinions for forms and methods of teaching used od lower stages of universities

    Directory of Open Access Journals (Sweden)

    Rudolf Šrámek

    2005-01-01

    Full Text Available Competent persons show, that more than 90% of teachers of Czech elementary schools and secondary schools until and since of 90-s of last century used and still use stereotype forms and methods of teaching; these procedures, which are little autonomic, formative and social. Procedures of sharing know- ledge to students and underestimating of deducing of knowledge with students.

  10. Development and Statistical Validation of Spectrophotometric Methods for the Estimation of Nabumetone in Tablet Dosage Form

    Directory of Open Access Journals (Sweden)

    A. R. Rote

    2010-01-01

    Full Text Available Three new simple, economic spectrophotometric methods were developed and validated for the estimation of nabumetone in bulk and tablet dosage form. First method includes determination of nabumetone at absorption maxima 330 nm, second method applied was area under curve for analysis of nabumetone in the wavelength range of 326-334 nm and third method was First order derivative spectra with scaling factor 4. Beer law obeyed in the concentration range of 10-30 μg/mL for all three methods. The correlation coefficients were found to be 0.9997, 0.9998 and 0.9998 by absorption maxima, area under curve and first order derivative spectra. Results of analysis were validated statistically and by performing recovery studies. The mean percent recoveries were found satisfactory for all three methods. The developed methods were also compared statistically using one way ANOVA. The proposed methods have been successfully applied for the estimation of nabumetone in bulk and pharmaceutical tablet dosage form.

  11. Five-point form of the nodal diffusion method and comparison with finite-difference

    International Nuclear Information System (INIS)

    Azmy, Y.Y.

    1988-01-01

    Nodal Methods have been derived, implemented and numerically tested for several problems in physics and engineering. In the field of nuclear engineering, many nodal formalisms have been used for the neutron diffusion equation, all yielding results which were far more computationally efficient than conventional Finite Difference (FD) and Finite Element (FE) methods. However, not much effort has been devoted to theoretically comparing nodal and FD methods in order to explain the very high accuracy of the former. In this summary we outline the derivation of a simple five-point form for the lowest order nodal method and compare it to the traditional five-point, edge-centered FD scheme. The effect of the observed differences on the accuracy of the respective methods is established by considering a simple test problem. It must be emphasized that the nodal five-point scheme derived here is mathematically equivalent to previously derived lowest order nodal methods. 7 refs., 1 tab

  12. Using stable isotopes to monitor forms of sulfur during desulfurization processes: A quick screening method

    Science.gov (United States)

    Liu, Chao-Li; Hackley, Keith C.; Coleman, D.D.; Kruse, C.W.

    1987-01-01

    A method using stable isotope ratio analysis to monitor the reactivity of sulfur forms in coal during thermal and chemical desulfurization processes has been developed at the Illinois State Geological Survey. The method is based upon the fact that a significant difference exists in some coals between the 34S/32S ratios of the pyritic and organic sulfur. A screening method for determining the suitability of coal samples for use in isotope ratio analysis is described. Making these special coals available from coal sample programs would assist research groups in sorting out the complex sulfur chemistry which accompanies thermal and chemical processing of high sulfur coals. ?? 1987.

  13. USING THE METHOD KINESIOTAPING IN REHABILITATION OF CHILDREN WITH HEMIPARETIC FORM OF CEREBRAL PALSY

    Directory of Open Access Journals (Sweden)

    Vladimir Evgenevich Tuchkov

    2016-08-01

    Full Text Available The study examines the impact of a new kind of impact in the rehabilitation of hemiparetic form of cerebral palsy – a method kinesiotaping «Concept 4 tapes». Within this framework, the receptor patient unit gradually turned on, resulting in a restructuring of the program abnormal movement, the conditions of use of other methods to increase the efficiency and depth of the order of their influence. The advantage of a technique kinesiotaping is the standard approach, allowing you to apply effects diagram method to all patients without loss of efficacy of therapeutic effects.

  14. A Validated RP-HPLC Method for the Determination of Atazanavir in Pharmaceutical Dosage Form

    Directory of Open Access Journals (Sweden)

    K. Srinivasu

    2011-01-01

    Full Text Available A validated RP HPLC method for the estimation of atazanavir in capsule dosage form on YMC ODS 150 × 4.6 mm, 5 μ column using mobile phase composition of ammonium dihydrogen phosphate buffer (pH 2.5 with acetonitrile (55:45 v/v. Flow rate was maintained at 1.5 mL/min with 288 nm UV detection. The retention time obtained for atazanavir was at 4.7 min. The detector response was linear in the concentration range of 30 - 600 μg/mL. This method has been validated and shown to be specific, sensitive, precise, linear, accurate, rugged, robust and fast. Hence, this method can be applied for routine quality control of atazanavir in capsule dosage forms as well as in bulk drug.

  15. Collaboration Patterns as a Function of Article Genre among Mixed Researchers: A Mixed Methods Bibliometric Study

    Science.gov (United States)

    Jordan, John; Wachsmann, Melanie; Hoisington, Susan; Gonzalez, Vanessa; Valle, Rachel; Lambert, Jarod; Aleisa, Majed; Wilcox, Rachael; Benge, Cindy L.; Onwuegbuzie, Anthony J.

    2017-01-01

    Surprisingly, scant information exists regarding the collaboration patterns of mixed methods researchers. Thus, the purpose of this mixed methods bibliometric study was to examine (a) the distribution of the number of co-authors in articles published in the flagship mixed methods research journal (i.e., "Journal of Mixed Methods…

  16. Method for Forming Fiber Reinforced Composite Bodies with Graded Composition and Stress Zones

    Science.gov (United States)

    Singh, Mrityunjay (Inventor); Levine, Stanley R. (Inventor); Smialek, James A. (Inventor)

    1999-01-01

    A near-net, complex shaped ceramic fiber reinforced silicon carbide based composite bodies with graded compositions and stress zones is disclosed. To provide the composite a fiber preform is first fabricated and an interphase is applied by chemical vapor infiltration, sol-gel or polymer processes. This first body is further infiltrated with a polymer mixture containing carbon, and/or silicon carbide, and additional oxide, carbide, or nitride phases forming a second body. One side of the second body is spray coated or infiltrated with slurries containing high thermal expansion and oxidation resistant. crack sealant phases and the other side of this second body is coated with low expansion phase materials to form a third body. This third body consisting of porous carbonaceous matrix surrounding the previously applied interphase materials, is then infiltrated with molten silicon or molten silicon-refractory metal alloys to form a fourth body. The resulting fourth body comprises dense composites consisting of fibers with the desired interphase which are surrounded by silicon carbide and other second phases materials at the outer and inner surfaces comprising material of silicon, germanium, refractory metal suicides, borides, carbides, oxides, and combinations thereof The resulting composite fourth body has different compositional patterns from one side to the other.

  17. Reliability Estimation of the Pultrusion Process Using the First-Order Reliability Method (FORM)

    DEFF Research Database (Denmark)

    Baran, Ismet; Tutum, Cem Celal; Hattel, Jesper Henri

    2013-01-01

    In the present study the reliability estimation of the pultrusion process of a flat plate is analyzed by using the first order reliability method (FORM). The implementation of the numerical process model is validated by comparing the deterministic temperature and cure degree profiles...... with corresponding analyses in the literature. The centerline degree of cure at the exit (CDOCE) being less than a critical value and the maximum composite temperature (Tmax) during the process being greater than a critical temperature are selected as the limit state functions (LSFs) for the FORM. The cumulative...

  18. Recombination pattern reanalysis of some HIV-1 circulating recombination forms suggest the necessity and difficulty of revision.

    Directory of Open Access Journals (Sweden)

    Lei Jia

    Full Text Available Recombination is one of the major mechanisms underlying the generation of HIV-1 variability. Currently 61 circulating recombinant forms of HIV-1 have been identified. With the development of recombination detection techniques and accumulation of HIV-1 reference stains, more accurate mosaic structures of circulating recombinant forms (CRFs, like CRF04 and CRF06, have undergone repeated analysis and upgrades. Such revisions may also be necessary for other CRFs. Unlike previous studies, whose results are based primarily on a single recombination detection program, the current study was based on multiple recombination analysis, which may have produced more impartial results.Representative references of 3 categories of intersubtype recombinants were selected, including BC recombinants (CRF07 and CRF08, BG recombinants (CRF23 and CRF24, and BF recombinants (CRF38 and CRF44. They were reanalyzed in detail using both the jumping profile hidden Markov model and RDP3.The results indicate that revisions and upgrades are very necessary and the entire re-analysis suggested 2 types of revision: (i length of inserted fragments; and (ii number of inserted fragments. The reanalysis also indicated that determination of small regions of about 200 bases or fewer should be performed with more caution.Results indicated that the involvement of multiple recombination detection programs is very necessary. Additionally, results suggested two major challenges, one involving the difficulty of accurately determining the locations of breakpoints and the second involving identification of small regions of about 200 bases or fewer with greater caution. Both indicate the complexity of HIV-1 recombination. The resolution would depend critically on development of a recombination analysis algorithm, accumulation of HIV-1 stains, and a higher sequencing quality. With the changes in recombination pattern, phylogenetic relationships of some CRFs may also change. All these results may

  19. A new method for designing dual foil electron beam forming systems. I. Introduction, concept of the method

    International Nuclear Information System (INIS)

    Adrich, Przemysław

    2016-01-01

    In Part I of this work existing methods and problems in dual foil electron beam forming system design are presented. On this basis, a new method of designing these systems is introduced. The motivation behind this work is to eliminate the shortcomings of the existing design methods and improve overall efficiency of the dual foil design process. The existing methods are based on approximate analytical models applied in an unrealistically simplified geometry. Designing a dual foil system with these methods is a rather labor intensive task as corrections to account for the effects not included in the analytical models have to be calculated separately and accounted for in an iterative procedure. To eliminate these drawbacks, the new design method is based entirely on Monte Carlo modeling in a realistic geometry and using physics models that include all relevant processes. In our approach, an optimal configuration of the dual foil system is found by means of a systematic, automatized scan of the system performance in function of parameters of the foils. The new method, while being computationally intensive, minimizes the involvement of the designer and considerably shortens the overall design time. The results are of high quality as all the relevant physics and geometry details are naturally accounted for. To demonstrate the feasibility of practical implementation of the new method, specialized software tools were developed and applied to solve a real life design problem, as described in Part II of this work.

  20. A new method for designing dual foil electron beam forming systems. I. Introduction, concept of the method

    Energy Technology Data Exchange (ETDEWEB)

    Adrich, Przemysław, E-mail: Przemyslaw.Adrich@ncbj.gov.pl

    2016-05-01

    In Part I of this work existing methods and problems in dual foil electron beam forming system design are presented. On this basis, a new method of designing these systems is introduced. The motivation behind this work is to eliminate the shortcomings of the existing design methods and improve overall efficiency of the dual foil design process. The existing methods are based on approximate analytical models applied in an unrealistically simplified geometry. Designing a dual foil system with these methods is a rather labor intensive task as corrections to account for the effects not included in the analytical models have to be calculated separately and accounted for in an iterative procedure. To eliminate these drawbacks, the new design method is based entirely on Monte Carlo modeling in a realistic geometry and using physics models that include all relevant processes. In our approach, an optimal configuration of the dual foil system is found by means of a systematic, automatized scan of the system performance in function of parameters of the foils. The new method, while being computationally intensive, minimizes the involvement of the designer and considerably shortens the overall design time. The results are of high quality as all the relevant physics and geometry details are naturally accounted for. To demonstrate the feasibility of practical implementation of the new method, specialized software tools were developed and applied to solve a real life design problem, as described in Part II of this work.

  1. Proposed waste form performance criteria and testing methods for low-level mixed waste

    International Nuclear Information System (INIS)

    Franz, E.M.; Fuhrmann, M.; Bowerman, B.

    1995-01-01

    Proposed waste form performance criteria and testing methods were developed as guidance in judging the suitability of solidified waste as a physico-chemical barrier to releases of radionuclides and RCRA regulated hazardous components. The criteria follow from the assumption that release of contaminants by leaching is the single most important property for judging the effectiveness of a waste form. A two-tier regimen is proposed. The first tier consists of a leach test designed to determine the net, forward leach rate of the solidified waste and a leach test required by the Environmental Protection Agency (EPA). The second tier of tests is to determine if a set of stresses (i.e., radiation, freeze-thaw, wet-dry cycling) on the waste form adversely impacts its ability to retain contaminants and remain physically intact. In the absence of site-specific performance assessments (PA), two generic modeling exercises are described which were used to calculate proposed acceptable leachates

  2. Flexible barrier film, method of forming same, and organic electronic device including same

    Science.gov (United States)

    Blizzard, John; Tonge, James Steven; Weidner, William Kenneth

    2013-03-26

    A flexible barrier film has a thickness of from greater than zero to less than 5,000 nanometers and a water vapor transmission rate of no more than 1.times.10.sup.-2 g/m.sup.2/day at 22.degree. C. and 47% relative humidity. The flexible barrier film is formed from a composition, which comprises a multi-functional acrylate. The composition further comprises the reaction product of an alkoxy-functional organometallic compound and an alkoxy-functional organosilicon compound. A method of forming the flexible barrier film includes the steps of disposing the composition on a substrate and curing the composition to form the flexible barrier film. The flexible barrier film may be utilized in organic electronic devices.

  3. A novel method for spectrophotometric determination of pregabalin in pure form and in capsules

    Directory of Open Access Journals (Sweden)

    Gaur Prateek

    2011-10-01

    Full Text Available Abstract Background Pregabalin, a γ-amino-n-butyric acid derivative, is an antiepileptic drug not yet official in any pharmacopeia and development of analytical procedures for this drug in bulk/formulation forms is a necessity. We herein, report a new, simple, extraction free, cost effective, sensitive and reproducible spectrophotometric method for the determination of the pregabalin. Results Pregabalin, as a primary amine was reacted with ninhydrin in phosphate buffer pH 7.4 to form blue violet colored chromogen which could be measured spectrophotometrically at λmax 402.6 nm. The method was validated with respect to linearity, accuracy, precision and robustness. The method showed linearity in a wide concentration range of 50-1000 μg mL-1 with good correlation coefficient (0.992. The limits of assays detection was found to be 6.0 μg mL-1 and quantitation limit was 20.0 μg mL-1. The suggested method was applied to the determination of the drug in capsules. No interference could be observed from the additives in the capsules. The percentage recovery was found to be 100.43 ± 1.24. Conclusion The developed method was successfully validated and applied to the determination of pregabalin in bulk and pharmaceutical formulations without any interference from common excipients. Hence, this method can be potentially useful for routine laboratory analysis of pregabalin.

  4. Ducks in space: from nonlinear absolute instability to noise-sustained structures in a pattern-forming system

    Science.gov (United States)

    Avitabile, D.; Desroches, M.; Knobloch, E.; Krupa, M.

    2017-11-01

    A subcritical pattern-forming system with nonlinear advection in a bounded domain is recast as a slow-fast system in space and studied using a combination of geometric singular perturbation theory and numerical continuation. Two types of solutions describing the possible location of stationary fronts are identified, whose origin is traced to the onset of convective and absolute instability when the system is unbounded. The former are present only for non-zero upstream boundary conditions and provide a quantitative understanding of noise-sustained structures in systems of this type. The latter correspond to the onset of a global mode and are present even with zero upstream boundary conditions. The role of canard trajectories in the nonlinear transition between these states is clarified and the stability properties of the resulting spatial structures are determined. Front location in the convective regime is highly sensitive to the upstream boundary condition, and its dependence on this boundary condition is studied using a combination of numerical continuation and Monte Carlo simulations of the partial differential equation. Statistical properties of the system subjected to random or stochastic boundary conditions at the inlet are interpreted using the deterministic slow-fast spatial dynamical system.

  5. Atypical Enteropathogenic Escherichia coli Strains form Biofilm on Abiotic Surfaces Regardless of Their Adherence Pattern on Cultured Epithelial Cells

    Directory of Open Access Journals (Sweden)

    Hebert F. Culler

    2014-01-01

    Full Text Available The aim of this study was to determine the capacity of biofilm formation of atypical enteropathogenic Escherichia coli (aEPEC strains on abiotic and biotic surfaces. Ninety-one aEPEC strains, isolated from feces of children with diarrhea, were analyzed by the crystal violet (CV assay on an abiotic surface after 24 h of incubation. aEPEC strains representing each HEp-2 cell type of adherence were analyzed after 24 h and 6, 12, and 18 days of incubation at 37°C on abiotic and cell surfaces by CFU/cm2 counting and confocal laser scanning microscopy (CLSM. Biofilm formation on abiotic surfaces occurred in 55 (60.4% of the aEPEC strains. There was no significant difference in biofilm biomass formation on an abiotic versus prefixed cell surface. The biofilms could be visualized by CLSM at various developmental stages. aEPEC strains are able to form biofilm on an abiotic surface with no association with their adherence pattern on HEp-2 cells with the exception of the strains expressing UND (undetermined adherence. This study revealed the capacity of adhesion and biofilm formation by aEPEC strains on abiotic and biotic surfaces, possibly playing a role in pathogenesis, mainly in cases of persistent diarrhea.

  6. Reliability of different methods used for forming of working samples in the laboratory for seed testing

    Directory of Open Access Journals (Sweden)

    Opra Branislava

    2000-01-01

    Full Text Available The testing of seed quality starts from the moment a sample is formed in a warehouse during processing or packaging of the seed. The seed sampling as the process of obtaining the working sample also assumes each step undertaken during its testing in the laboratory. With the aim of appropriate forming of a seed sample in the laboratory, the usage of seed divider is prescribed for large seeded species (such as seed the size of wheat or larger (ISTA Rules, 1999. The aim of this paper was the comparison of different methods used for obtaining the working samples of maize and wheat seeds using conical, soil and centrifugal dividers. The number of seed of added admixtures confirmed the reliability of working samples formation. To each maize sample (1000 g 10 seeds of the following admixtures were added: Zea mays L. (red pericarp, Hordeum vulgäre L., Triticum aestivum L., and Glycine max (L. Merr. Two methods were used for formation of maze seed working sample. To wheat samples (1000 g 10 seeds of each of the following species were added: Avena saliva (hulled seeds, Hordeum vulgäre L., Galium tricorne Stokes, and Polygonum lapatifolmm L. For formation of wheat seed working samples four methods were used. Optimum of 9, but not less than 7 seeds of admixture were due to be determined in the maize seed working sample, while for wheat, at least one seed of admixture was expected to be found in the working sample. The obtained results confirmed that the formation of the maize seed working samples was the most reliable when centrifugal divider, the first method was used (average of admixture - 9.37. From the observed admixtures the seed of Triticum aestivum L. was the most uniformly distributed, the first method also being used (6.93. The second method gains high average values satisfying the given criterion, but it should be used with previous homogenization of the sample being tested. The forming of wheat seed working samples is the most reliable if the

  7. General form of the Euler-Poisson-Darboux equation and application of the transmutation method

    Directory of Open Access Journals (Sweden)

    Elina L. Shishkina

    2017-07-01

    Full Text Available In this article, we find solution representations in the compact integral form to the Cauchy problem for a general form of the Euler-Poisson-Darboux equation with Bessel operators via generalized translation and spherical mean operators for all values of the parameter k, including also not studying before exceptional odd negative values. We use a Hankel transform method to prove results in a unified way. Under additional conditions we prove that a distributional solution is a classical one too. A transmutation property for connected generalized spherical mean is proved and importance of applying transmutation methods for differential equations with Bessel operators is emphasized. The paper also contains a short historical introduction on differential equations with Bessel operators and a rather detailed reference list of monographs and papers on mathematical theory and applications of this class of differential equations.

  8. Influences of rolling method on deformation force in cold roll-beating forming process

    Science.gov (United States)

    Su, Yongxiang; Cui, Fengkui; Liang, Xiaoming; Li, Yan

    2018-03-01

    In process, the research object, the gear rack was selected to study the influence law of rolling method on the deformation force. By the mean of the cold roll forming finite element simulation, the variation regularity of radial and tangential deformation was analysed under different rolling methods. The variation of deformation force of the complete forming racks and the single roll during the steady state under different rolling modes was analyzed. The results show: when upbeating and down beating, radial single point average force is similar, the tangential single point average force gap is bigger, the gap of tangential single point average force is relatively large. Add itionally, the tangential force at the time of direct beating is large, and the dire ction is opposite with down beating. With directly beating, deformation force loading fast and uninstall slow. Correspondingly, with down beating, deformat ion force loading slow and uninstall fast.

  9. Radial arrays of nano-electrospray ionization emitters and methods of forming electrosprays

    Science.gov (United States)

    Kelly, Ryan T [West Richland, WA; Tang, Keqi [Richland, WA; Smith, Richard D [Richland, WA

    2010-10-19

    Electrospray ionization emitter arrays, as well as methods for forming electrosprays, are described. The arrays are characterized by a radial configuration of three or more nano-electrospray ionization emitters without an extractor electrode. The methods are characterized by distributing fluid flow of the liquid sample among three or more nano-electrospray ionization emitters, forming an electrospray at outlets of the emitters without utilizing an extractor electrode, and directing the electrosprays into an entrance to a mass spectrometry device. Each of the nano-electrospray ionization emitters can have a discrete channel for fluid flow. The nano-electrospray ionization emitters are circularly arranged such that each is shielded substantially equally from an electrospray-inducing electric field.

  10. Rare Earth Oxide Fluoride Nanoparticles And Hydrothermal Method For Forming Nanoparticles

    Science.gov (United States)

    Fulton, John L.; Hoffmann, Markus M.

    2003-12-23

    A hydrothermal method for forming nanoparticles of a rare earth element, oxygen and fluorine has been discovered. Nanoparticles comprising a rare earth element, oxygen and fluorine are also described. These nanoparticles can exhibit excellent refractory properties as well as remarkable stability in hydrothermal conditions. The nanoparticles can exhibit excellent properties for numerous applications including fiber reinforcement of ceramic composites, catalyst supports, and corrosion resistant coatings for high-temperature aqueous solutions.

  11. DIAGNOSTIC CHARACTERISTICS OF THE COMPUTER TESTS FORMED BY METHOD OF RESTORED FRAGMENTS

    OpenAIRE

    Oleksandr O. Petkov

    2013-01-01

    Definition of validity and reliability of tests which are formed by a method of restored fragments is considered in the article. The structure of the controlled theoretical material of limit field of knowledge, language expressions that describe the subject of control, and reliability of test, is analyzed. The technique of definition of the most important components of reliability of the considered tests is given: reliability of quantitative determination of coefficient of assimilation and te...

  12. A Simple Method for Forming Hybrid Core-Shell Nanoparticles Suspended in Water

    Directory of Open Access Journals (Sweden)

    Jean-Christophe Daigle

    2008-01-01

    addition fragmentation chain transfer (RAFT polymerization as dispersant. Then, the resulting dispersion is engaged in a radical emulsion polymerization process whereby a hydrophobic organic monomer (styrene and butyl acrylate is polymerized to form the shell of the hybrid nanoparticle. This method is extremely versatile, allowing the preparation of a variety of nanocomposites with metal oxides (alumina, rutile, anatase, barium titanate, zirconia, copper oxide, metals (Mo, Zn, and even inorganic nitrides (Si3N4.

  13. On the asymptotic form of the recursion method basis vectors for periodic Hamiltonians

    International Nuclear Information System (INIS)

    O'Reilly, E.P.; Weaire, D.

    1984-01-01

    The authors present the first detailed study of the recursion method basis vectors for the case of a periodic Hamiltonian. In the examples chosen, the probability density scales linearly with n as n → infinity, whenever the local density of states is bounded. Whenever it is unbounded and the recursion coefficients diverge, different scaling behaviour is found. These findings are explained and a scaling relationship between the asymptotic forms of the recursion coefficients and basis vectors is proposed. (author)

  14. A method for autoradiographic studies of single clones of plaque forming cells

    International Nuclear Information System (INIS)

    Andersen, V.; Lefkovits, I.; Rigshospitalet, Copenhagen

    1977-01-01

    By limiting dilution of B lymphocytes from spleens of immunized mice, microcultures were obtained that contained only one clone of plaque forming cells (PFC). The cultured cells were labelled with [ 14 C]thymidine for varying period of time. Plaques were obtained in monolayers of sheep erythrocytes in plastic dishes. After fixation with glutaraldehyde, the bottoms of the dishes were stripped off and autoradiograms prepared. By this method, it is possible to determine the proportion of labelled PFC within a given clone and to quantitate the incorporation of label. The method described can be applied to study the incorporation of other labelled molecules and for cytochemical investigations

  15. First-order systems of linear partial differential equations: normal forms, canonical systems, transform methods

    Directory of Open Access Journals (Sweden)

    Heinz Toparkus

    2014-04-01

    Full Text Available In this paper we consider first-order systems with constant coefficients for two real-valued functions of two real variables. This is both a problem in itself, as well as an alternative view of the classical linear partial differential equations of second order with constant coefficients. The classification of the systems is done using elementary methods of linear algebra. Each type presents its special canonical form in the associated characteristic coordinate system. Then you can formulate initial value problems in appropriate basic areas, and you can try to achieve a solution of these problems by means of transform methods.

  16. Numerical form-finding method for large mesh reflectors with elastic rim trusses

    Science.gov (United States)

    Yang, Dongwu; Zhang, Yiqun; Li, Peng; Du, Jingli

    2018-06-01

    Traditional methods for designing a mesh reflector usually treat the rim truss as rigid. Due to large aperture, light weight and high accuracy requirements on spaceborne reflectors, the rim truss deformation is indeed not negligible. In order to design a cable net with asymmetric boundaries for the front and rear nets, a cable-net form-finding method is firstly introduced. Then, the form-finding method is embedded into an iterative approach for designing a mesh reflector considering the elasticity of the supporting rim truss. By iterations on form-findings of the cable-net based on the updated boundary conditions due to the rim truss deformation, a mesh reflector with a fairly uniform tension distribution in its equilibrium state could be finally designed. Applications on offset mesh reflectors with both circular and elliptical rim trusses are illustrated. The numerical results show the effectiveness of the proposed approach and that a circular rim truss is more stable than an elliptical rim truss.

  17. Development of polymer film dosage forms of lidocaine for buccal administration: II. Comparison of preparation methods.

    Science.gov (United States)

    Okamoto, Hirokazu; Nakamori, Takahiko; Arakawa, Yotaro; Iida, Kotaro; Danjo, Kazumi

    2002-11-01

    In previous studies, we prepared film dosage forms of lidocaine (LC) with hydroxypropylcellulose (HPC) as a film base using the solvent evaporation (SE) method. However, from the viewpoint of environmental issues, a reduction in organic solvent use in pharmaceutical and other industries is required. In this study, we prepared the LC films by direct compression of the physical mixture (DCPM method) and direct compression of the spray dried powder (DCSD method). Magnesium stearate, which was required as a lubricant for direct compression, showed no effect on the LC release rate. The LC release rate (%/h) was independent of the compression pressure, but a higher pressure was preferable to easily remove the film from the punches. An increase in the film weight decreased the LC release rate expressed in %/h, whereas no significant effect of film weight was observed on the LC release rate from unit surface area expressed in mg/h/cm(2). The LC release rate (%/h) was independent of the LC content, suggesting that the LC release rate (mg/h) can be quantitatively controlled by changing the LC content in the formulation. The LC release rate and penetration rate were affected by the preparation method; that is, DCPM method dosage form. Copyright 2002 Wiley-Liss, Inc. and the American Pharmaceutical Association J Pharm Sci 91:2424-2432, 2002

  18. Study on the traditional pattern retrieval method of minorities in Gansu province

    Science.gov (United States)

    Zheng, Gang; Wang, Beizhan; Sun, Yuchun; Xu, Jin

    2018-03-01

    The traditional patterns of ethnic minorities in gansu province are ethnic arts with strong ethnic characteristics. It is the crystallization of the hard work and wisdom of minority nationalities in gansu province. Unique traditional patterns of ethnic minorities in Gansu province with rich ethnic folk arts, is the crystallization of geographical environment in Gansu minority diligence and wisdom. By using the Surf feature point identification algorithm, the feature point extractor in OpenCV is used to extract the feature points. And the feature points are applied to compare the pattern features to find patterns similar to the artistic features. The application of this method can quickly or efficiently extract pattern information in a database.

  19. Kinetic spectrophotometric method for the determination of perindopril erbumine in pure and commercial dosage forms

    Directory of Open Access Journals (Sweden)

    Nafisur Rahman

    2017-02-01

    Full Text Available A kinetic spectrophotometric method has been developed for the determination of perindopril erbumine in pure and commercial dosage forms. The method is based on the reaction of drug with potassium permanganate in alkaline medium at room temperature (30 ± 1 °C. The reaction was followed spectrophotometrically by measuring the increase in absorbance with time at 603 nm and the initial rate, fixed time (at 8.0 min and equilibrium time (at 90.0 min methods were adopted for constructing the calibration graphs. All the calibration graphs are linear in the concentration range of 5.0–50.0 μg/ml. The limits of detection for initial rate, fixed time and equilibrium time methods were 0.752, 0.882 and 1.091 μg/ml, respectively. The activation parameters such as Ea, ΔH‡, ΔS‡ and ΔG‡ were also determined for the reaction and found to be 60.93 kJ/mol, 56.45 kJ/mol, 74.16 J/K mol and −6.53 kJ/mol, respectively. The variables were optimized and the proposed methods are validated as per ICH guidelines. The method has been further applied to the determination of perindopril erbumine in commercial dosage forms. The analytical results of the proposed methods when compared with those of the reference method show no significant difference in accuracy and precision and have acceptable bias.

  20. Estimating the carbohydrate content of various forms of tobacco by phenol-sulfuric acid method.

    Science.gov (United States)

    Jain, Vardhaman Mulchand; Karibasappa, Gundabaktha Nagappa; Dodamani, Arun Suresh; Mali, Gaurao Vasant

    2017-01-01

    Due to consumption of various forms of tobacco in large amounts by Indian population, it has become a cause of concern for major oral diseases. In 2008, the WHO named tobacco as the world's single greatest cause of preventable death. It is also known that certain amount of carbohydrates are incorporated in processed tobacco to make it acceptable for consumption. Thus, its role in oral diseases becomes an important question at this point of time. Through this study, it is attempted to find out the carbohydrate content of various forms of tobacco by phenol-sulfuric acid method. Tobacco products selected for the study were Nandi hookah tambakhu (A), photo brand budhaa Punjabi snuff (B), Miraj (C), Gai-chhap tambakhu (D), Hanuman-chhap Pandharpuri tambakhu (E), and Hathi-chhap Bidi (F). The samples were decoded and transported to laboratory and tested at various concentrations by phenol-sulfuric acid method followed by ultraviolet spectrophotometry to determine their absorbance. The present study showed Hathi-chhap bidi/sample F had a maximum absorbance (1.995) at 10 μg/ml which is a smoking form of tobacco followed by rest all smokeless forms of tobacco, i.e. sample C (0.452), sample B (0.253), sample D (0.077), sample E (-0.018), and sample A (-0.127), respectively. As the concentration of tobacco sample increases, their absorbance increases which in turn is suggestive of increase in its carbohydrate concentration. Carbohydrates in the form of sugars, either inherently present or added in it during manufacturing can serve as a risk factor for higher incidence of dental caries.

  1. Surveillance of a nuclear reactor core by use of a pattern recognition method

    International Nuclear Information System (INIS)

    Invernizzi, Michel.

    1982-07-01

    A pattern recognition system is described for the surveillance of a PWR reactor. This report contains four chapters. The first one succinctly deals with statistical pattern recognition principles. In the second chapter we show how a surveillance problem may be treated by pattern recognition and we present methods for surveillances (detection of abnormalities), controls (kind of running recognition) and diagnotics (kind of abnormality recognition). The third chapter shows a surveillance method of a nuclear plant. The signals used are the neutron noise observations made by the ionization chambers inserted in the reactor. Abnormality is defined in opposition with the training set witch is supposed to be an exhaustive summary of normality. In the fourth chapter we propose a scheme for an adaptative recognition and a method based on classes modelisations by hyper-spheres. This method has been tested on simulated training sets in two-dimensional feature spaces. It gives solutions to problems of non-linear separability [fr

  2. A new method for designing dual foil electron beam forming systems. II. Feasibility of practical implementation of the method

    International Nuclear Information System (INIS)

    Adrich, Przemysław

    2016-01-01

    In Part I of this work a new method for designing dual foil electron beam forming systems was introduced. In this method, an optimal configuration of the dual foil system is found by means of a systematic, automatized scan of system performance in function of its parameters. At each point of the scan, Monte Carlo method is used to calculate the off-axis dose profile in water taking into account detailed and complete geometry of the system. The new method, while being computationally intensive, minimizes the involvement of the designer. In this Part II paper, feasibility of practical implementation of the new method is demonstrated. For this, a prototype software tools were developed and applied to solve a real life design problem. It is demonstrated that system optimization can be completed within few hours time using rather moderate computing resources. It is also demonstrated that, perhaps for the first time, the designer can gain deep insight into system behavior, such that the construction can be simultaneously optimized in respect to a number of functional characteristics besides the flatness of the off-axis dose profile. In the presented example, the system is optimized in respect to both, flatness of the off-axis dose profile and the beam transmission. A number of practical issues related to application of the new method as well as its possible extensions are discussed.

  3. Void Structures in Regularly Patterned ZnO Nanorods Grown with the Hydrothermal Method

    Directory of Open Access Journals (Sweden)

    Yu-Feng Yao

    2014-01-01

    Full Text Available The void structures and related optical properties after thermal annealing with ambient oxygen in regularly patterned ZnO nanrorod (NR arrays grown with the hydrothermal method are studied. In increasing the thermal annealing temperature, void distribution starts from the bottom and extends to the top of an NR in the vertical (c-axis growth region. When the annealing temperature is higher than 400°C, void distribution spreads into the lateral (m-axis growth region. Photoluminescence measurement shows that the ZnO band-edge emission, in contrast to defect emission in the yellow-red range, is the strongest under the n-ZnO NR process conditions of 0.003 M in Ga-doping concentration and 300°C in thermal annealing temperature with ambient oxygen. Energy dispersive X-ray spectroscopy data indicate that the concentration of hydroxyl groups in the vertical growth region is significantly higher than that in the lateral growth region. During thermal annealing, hydroxyl groups are desorbed from the NR leaving anion vacancies for reacting with cation vacancies to form voids.

  4. A new method for analysing socio-ecological patterns of vulnerability

    NARCIS (Netherlands)

    Kok, M.; Lüdeke, M.; Lucas, P.; Sterzel, T.; Walther, C.; Janssen, P.; Sietz, D.; Soysa, de I.

    2016-01-01

    This paper presents a method for the analysis of socio-ecological patterns of vulnerability of people being at risk of losing their livelihoods as a consequence of global environmental change. This method fills a gap in methodologies for vulnerability analysis by providing generalizations of the

  5. Flexible method for fabricating protein patterns on superhydrophobic platforms controlled by magnetic field.

    Science.gov (United States)

    Wang, Jian; Li, Hao; Zou, Haoyang; Wang, Chenmiao; Zhang, Hao; Mano, João F; Song, Wenlong

    2017-02-28

    Inspired by the rolling of water droplets on lotus leaves, we developed a novel, magnetic field-controlled patterning method for water-soluble proteins and other functional materials on superhydrophobic platforms. This simple method can be used to fabricate biochips and open micro-fluidic devices in a simple way.

  6. Design science research methods and patterns innovating information and communication technology

    CERN Document Server

    Vaishnavi, Vijay K

    2015-01-01

    Presenting innovative research methods, this second edition of a bestseller describes a simple and practical methodology for conducting cutting-edge design science research (DSR). It provides comprehensive guidance on how to conduct such research and supplies in-depth treatment of design science theory and the different types of theory that can be generated in design science research.Making novel use of the concept of patterns, it presents 84 research patterns for conducting effective DSR. It emphasizes design science theory throughout and is filled with practical examples of using patterns to

  7. Spectrophotometric method for simultaneous estimation of atazanavir sulfate and ritonavir in tablet dosage form

    Directory of Open Access Journals (Sweden)

    Disha A Patel

    2015-01-01

    Full Text Available Background: Ritonavir (RTV and atazanavir sulfate (ATV are protease inhibitor and RTV mostly used as a booster for increasing the bioavailability of other protease inhibitors like ATV. Aims: Quality assessment of the new dosage form of RTV and ATV i.e., tablets is very essential and hence this work deals with to develop sensitive, simple and precise method for simultaneous estimation of ATV and RTV in tablet dosage form by absorbance correction method. Materials and Methods: The present work was carried out on Shimadzu Ultraviolate(UV-1700 double beam spectrophotometer with 1 cm path length supported by S Shimadzu, model-1700(Japan, UV-Probe software, version 2.31 was used for spectral measurements with 10 mm matched quartz cells. Standard ATV and RTV were supplied by Cipla Pharmaceutical Ltd. Methanol was purchased from Finar Chemicals Pvt. Ltd. Results and Conclusion: The λmax or the absorption maxima for ATV and RTV were found to be 279 and 240 nm, respectively in methanol as solvent. The drugs follow Beer-Lambert′s law in the concentration range 30-90 and 10-30 μg/mL for ATV and RTV, respectively. The percentage recovery was found to be 100-100.33% and 100-101.5% for ATV and RTV, respectively. The method was validated for different parameters as per the International Conference for Harmonization Guidelines.

  8. Sound recovery via intensity variations of speckle pattern pixels selected with variance-based method

    Science.gov (United States)

    Zhu, Ge; Yao, Xu-Ri; Qiu, Peng; Mahmood, Waqas; Yu, Wen-Kai; Sun, Zhi-Bin; Zhai, Guang-Jie; Zhao, Qing

    2018-02-01

    In general, the sound waves can cause the vibration of the objects that are encountered in the traveling path. If we make a laser beam illuminate the rough surface of an object, it will be scattered into a speckle pattern that vibrates with these sound waves. Here, an efficient variance-based method is proposed to recover the sound information from speckle patterns captured by a high-speed camera. This method allows us to select the proper pixels that have large variances of the gray-value variations over time, from a small region of the speckle patterns. The gray-value variations of these pixels are summed together according to a simple model to recover the sound with a high signal-to-noise ratio. Meanwhile, our method will significantly simplify the computation compared with the traditional digital-image-correlation technique. The effectiveness of the proposed method has been verified by applying a variety of objects. The experimental results illustrate that the proposed method is robust to the quality of the speckle patterns and costs more than one-order less time to perform the same number of the speckle patterns. In our experiment, a sound signal of time duration 1.876 s is recovered from various objects with time consumption of 5.38 s only.

  9. Validated spectrophotometric methods for simultaneous determination of troxerutin and carbazochrome in dosage form

    Science.gov (United States)

    Khattab, Fatma I.; Ramadan, Nesrin K.; Hegazy, Maha A.; Al-Ghobashy, Medhat A.; Ghoniem, Nermine S.

    2015-03-01

    Four simple, accurate, sensitive and precise spectrophotometric methods were developed and validated for simultaneous determination of Troxerutin (TXN) and Carbazochrome (CZM) in their bulk powders, laboratory prepared mixtures and pharmaceutical dosage forms. Method A is first derivative spectrophotometry (D1) where TXN and CZM were determined at 294 and 483.5 nm, respectively. Method B is first derivative of ratio spectra (DD1) where the peak amplitude at 248 for TXN and 439 nm for CZM were used for their determination. Method C is ratio subtraction (RS); in which TXN was determined at its λmax (352 nm) in the presence of CZM which was determined by D1 at 483.5 nm. While, method D is mean centering of the ratio spectra (MCR) in which the mean centered values at 300 nm and 340.0 nm were used for the two drugs in a respective order. The two compounds were simultaneously determined in the concentration ranges of 5.00-50.00 μg mL-1 and 0.5-10.0 μg mL-1 for TXN and CZM, respectively. The methods were validated according to the ICH guidelines and the results were statistically compared to the manufacturer's method.

  10. Comparative analyses reveal discrepancies among results of commonly used methods for Anopheles gambiaemolecular form identification

    Directory of Open Access Journals (Sweden)

    Pinto João

    2011-08-01

    Full Text Available Abstract Background Anopheles gambiae M and S molecular forms, the major malaria vectors in the Afro-tropical region, are ongoing a process of ecological diversification and adaptive lineage splitting, which is affecting malaria transmission and vector control strategies in West Africa. These two incipient species are defined on the basis of single nucleotide differences in the IGS and ITS regions of multicopy rDNA located on the X-chromosome. A number of PCR and PCR-RFLP approaches based on form-specific SNPs in the IGS region are used for M and S identification. Moreover, a PCR-method to detect the M-specific insertion of a short interspersed transposable element (SINE200 has recently been introduced as an alternative identification approach. However, a large-scale comparative analysis of four widely used PCR or PCR-RFLP genotyping methods for M and S identification was never carried out to evaluate whether they could be used interchangeably, as commonly assumed. Results The genotyping of more than 400 A. gambiae specimens from nine African countries, and the sequencing of the IGS-amplicon of 115 of them, highlighted discrepancies among results obtained by the different approaches due to different kinds of biases, which may result in an overestimation of MS putative hybrids, as follows: i incorrect match of M and S specific primers used in the allele specific-PCR approach; ii presence of polymorphisms in the recognition sequence of restriction enzymes used in the PCR-RFLP approaches; iii incomplete cleavage during the restriction reactions; iv presence of different copy numbers of M and S-specific IGS-arrays in single individuals in areas of secondary contact between the two forms. Conclusions The results reveal that the PCR and PCR-RFLP approaches most commonly utilized to identify A. gambiae M and S forms are not fully interchangeable as usually assumed, and highlight limits of the actual definition of the two molecular forms, which might

  11. Contribution to an effective design method for stationary reaction-diffusion patterns

    Energy Technology Data Exchange (ETDEWEB)

    Szalai, István; Horváth, Judit [Laboratory of Nonlinear Chemical Dynamics, Institute of Chemistry, Eötvös Loránd University, P.O. Box 32, H-1518 Budapest 112 (Hungary); De Kepper, Patrick [Centre de Recherche Paul Pascal, CNRS, University of Bordeaux, 115, Avenue Schweitzer, F-33600 Pessac (France)

    2015-06-15

    The British mathematician Alan Turing predicted, in his seminal 1952 publication, that stationary reaction-diffusion patterns could spontaneously develop in reacting chemical or biochemical solutions. The first two clear experimental demonstrations of such a phenomenon were not made before the early 1990s when the design of new chemical oscillatory reactions and appropriate open spatial chemical reactors had been invented. Yet, the number of pattern producing reactions had not grown until 2009 when we developed an operational design method, which takes into account the feeding conditions and other specificities of real open spatial reactors. Since then, on the basis of this method, five additional reactions were shown to produce stationary reaction-diffusion patterns. To gain a clearer view on where our methodical approach on the patterning capacity of a reaction stands, numerical studies in conditions that mimic true open spatial reactors were made. In these numerical experiments, we explored the patterning capacity of Rabai's model for pH driven Landolt type reactions as a function of experimentally attainable parameters that control the main time and length scales. Because of the straightforward reversible binding of protons to carboxylate carrying polymer chains, this class of reaction is at the base of the chemistry leading to most of the stationary reaction-diffusion patterns presently observed. We compare our model predictions with experimental observations and comment on agreements and differences.

  12. Contribution to an effective design method for stationary reaction-diffusion patterns

    International Nuclear Information System (INIS)

    Szalai, István; Horváth, Judit; De Kepper, Patrick

    2015-01-01

    The British mathematician Alan Turing predicted, in his seminal 1952 publication, that stationary reaction-diffusion patterns could spontaneously develop in reacting chemical or biochemical solutions. The first two clear experimental demonstrations of such a phenomenon were not made before the early 1990s when the design of new chemical oscillatory reactions and appropriate open spatial chemical reactors had been invented. Yet, the number of pattern producing reactions had not grown until 2009 when we developed an operational design method, which takes into account the feeding conditions and other specificities of real open spatial reactors. Since then, on the basis of this method, five additional reactions were shown to produce stationary reaction-diffusion patterns. To gain a clearer view on where our methodical approach on the patterning capacity of a reaction stands, numerical studies in conditions that mimic true open spatial reactors were made. In these numerical experiments, we explored the patterning capacity of Rabai's model for pH driven Landolt type reactions as a function of experimentally attainable parameters that control the main time and length scales. Because of the straightforward reversible binding of protons to carboxylate carrying polymer chains, this class of reaction is at the base of the chemistry leading to most of the stationary reaction-diffusion patterns presently observed. We compare our model predictions with experimental observations and comment on agreements and differences

  13. Proposed waste form performance criteria and testing methods for low-level mixed waste

    International Nuclear Information System (INIS)

    Franz, E.M.; Fuhrmann, M.; Bowerman, B.; Bates, S.; Peters, R.

    1994-08-01

    This document describes proposed waste form performance criteria and testing method that could be used as guidance in judging viability of a waste form as a physico-chemical barrier to releases of radionuclides and RCRA regulated hazardous components. It is assumed that release of contaminants by leaching is the single most important property by which the effectiveness of a waste form is judged. A two-tier regimen is proposed. The first tier includes a leach test required by the Environmental Protection Agency and a leach test designed to determine the net forward leach rate for a variety of materials. The second tier of tests are to determine if a set of stresses (i.e., radiation, freeze-thaw, wet-dry cycling) on the waste form adversely impact its ability to retain contaminants and remain physically intact. It is recommended that the first tier tests be performed first to determine acceptability. Only on passing the given specifications for the leach tests should other tests be performed. In the absence of site-specific performance assessments (PA), two generic modeling exercises are described which were used to calculate proposed acceptable leach rates

  14. A high pressure liquid chromatography method for separation of prolactin forms.

    Science.gov (United States)

    Bell, Damon A; Hoad, Kirsten; Leong, Lillian; Bakar, Juwaini Abu; Sheehan, Paul; Vasikaran, Samuel D

    2012-05-01

    Prolactin has multiple forms and macroprolactin, which is thought not to be bioavailable, can cause a raised serum prolactin concentration. Gel filtration chromatography (GFC) is currently the gold standard method for separating macroprolactin, but is labour-intensive. Polyethylene glycol (PEG) precipitation is suitable for routine use but may not always be accurate. We developed a high pressure liquid chromatography (HPLC) assay for macroprolactin measurement. Chromatography was carried out using an Agilent Zorbax GF-250 (9.4 × 250 mm, 4 μm) size exclusion column and 50 mmol/L Tris buffer with 0.15 mmol/L NaCl at pH 7.2 as mobile phase, with a flow rate of 1 mL/min. Serum or plasma was diluted 1:1 with mobile phase and filtered and 100 μL injected. Fractions of 155 μL were collected for prolactin measurement and elution profile plotted. The area under the curve of each prolactin peak was calculated to quantify each prolactin form, and compared with GFC. Clear separation of monomeric-, big- and macroprolactin forms was achieved. Quantification was comparable to GFC and precision was acceptable. Total time from injection to collection of the final fraction was 16 min. We have developed an HPLC method for quantification of macroprolactin, which is rapid and easy to perform and therefore can be used for routine measurement.

  15. Development and Validation of UV Spectrophotometric Method For Estimation of Dolutegravir Sodium in Tablet Dosage Form

    International Nuclear Information System (INIS)

    Balasaheb, B.G.

    2015-01-01

    A simple, rapid, precise and accurate spectrophotometric method has been developed for quantitative analysis of Dolutegravir sodium in tablet formulations. The initial stock solution of Dolutegravir sodium was prepared in methanol solvent and subsequent dilution was done in water. The standard solution of Dolutegravir sodium in water showed maximum absorption at wavelength 259.80 nm. The drug obeyed Beer-Lamberts law in the concentration range of 5-40 μg/ mL with coefficient of correlation (R"2) was 0.9992. The method was validated as per the ICH guidelines. The developed method can be adopted in routine analysis of Dolutegravir sodium in bulk or tablet dosage form and it involves relatively low cost solvents and no complex extraction techniques. (author)

  16. Development of alternative methods for the determination of raloxifene hydrochloride in tablet dosage form

    Directory of Open Access Journals (Sweden)

    Fernanda Rodrigues Salazar

    2015-06-01

    Full Text Available Three methods are proposed for the quantitative determination of raloxifene hydrochloride in pharmaceutical dosage form: ultraviolet method (UV high performance liquid chromatography (HPLC and micellar capillary electrophoresis (MEKC. These methods were developed and validated and showed good linearity, precision and accuracy. Also they demonstrated to be specific and robust. The HPLC and MEKC methods were tested in regards to be stability indicating methods and they showed to have this attribute. The UV method used methanol as solvent and optimal wavelength at 284 nm, obeying Lambert-Beer law in these conditions. The chromatographic conditions for the HPLC method included: NST column C18 (250 x 4.6 mm x 5 µm, mobile phase water:acetonitrile:triethylamine (67:33:0,3 v/v, pH 3.5, flow rate 1.0 mL min-1, injection volume 20.0 µl, UV detection 287 nm and analysis temperature 30 °C. The MEKC method was performed on a fused-silica capillary (40 cm effective length x 50 µm i.d. using as background electrolyte 35.0 mmol L-1 borate buffer and 50.0 mmol L-1 anionic detergent sodium dodecyl sulfate (SDS at pH 8.8. The capillary temperature was 32°C, applied voltage 25 kV, UV detection at 280 nm and injection was perfomed at 45 mBar for 4 s, hydrodimanic mode. In this MEKC method, potassium diclofenac (200.0 µg mL-1 was used as internal standard. All these methods were statistically analyzed and demonstrated to be equivalent for quantitative analysis of RLX in tablets and were successfully applied for the determination of the drug.

  17. METHOD OF GROUP OBJECTS FORMING FOR SPACE-BASED REMOTE SENSING OF THE EARTH

    Directory of Open Access Journals (Sweden)

    A. N. Grigoriev

    2015-07-01

    Full Text Available Subject of Research. Research findings of the specific application of space-based optical-electronic and radar means for the Earth remote sensing are considered. The subject matter of the study is the current planning of objects survey on the underlying surface in order to increase the effectiveness of sensing system due to the rational use of its resources. Method. New concept of a group object, stochastic swath and stochastic length of the route is introduced. The overview of models for single, group objects and their parameters is given. The criterion for the existence of the group object based on two single objects is formulated. The method for group objects formation while current survey planning has been developed and its description is presented. The method comprises several processing stages for data about objects with the calculation of new parameters, the stochastic characteristics of space means and validates the spatial size of the object value of the stochastic swath and stochastic length of the route. The strict mathematical description of techniques for model creation of a group object based on data about a single object and onboard special complex facilities in difficult conditions of registration of spatial data is given. Main Results. The developed method is implemented on the basis of modern geographic information system in the form of a software tool layout with advanced tools of processing and analysis of spatial data in vector format. Experimental studies of the forming method for the group of objects were carried out on a different real object environment using the parameters of modern national systems of the Earth remote sensing detailed observation Canopus-B and Resurs-P. Practical Relevance. The proposed models and method are focused on practical implementation using vector spatial data models and modern geoinformation technologies. Practical value lies in the reduction in the amount of consumable resources by means of

  18. Static and Vibrational Analysis of Partially Composite Beams Using the Weak-Form Quadrature Element Method

    Directory of Open Access Journals (Sweden)

    Zhiqiang Shen

    2012-01-01

    Full Text Available Deformation of partially composite beams under distributed loading and free vibrations of partially composite beams under various boundary conditions are examined in this paper. The weak-form quadrature element method, which is characterized by direct evaluation of the integrals involved in the variational description of a problem, is used. One quadrature element is normally sufficient for a partially composite beam regardless of the magnitude of the shear connection stiffness. The number of integration points in a quadrature element is adjustable in accordance with convergence requirement. Results are compared with those of various finite element formulations. It is shown that the weak form quadrature element solution for partially composite beams is free of slip locking, and high computational accuracy is achieved with smaller number of degrees of freedom. Besides, it is found that longitudinal inertia of motion cannot be simply neglected in assessment of dynamic behavior of partially composite beams.

  19. Comparison of bar pattern and edge method for MTF measurement in radiology quality control

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez, M.; Alves, A.F.F; Bacchim Neto, F.A.; Pavan, A.L.M.; Rosa, M.E.D.; Miranda, J.R.A.; Pina, D.R. de, E-mail: drpina@fmb.unesp.br [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Botucatu, SP (Brazil)

    2015-08-15

    Spatial resolution is one of the parameters that is routinely checked during acceptance procedures and regular quality control measurements. The spatial resolution of a radiographic imaging device is most appropriately expressed in terms of its modulation transfer function (MTF), which indicates the decline of detector spatial resolution with spatial frequency. Traditionally used methods of MTF measurement involve imaging either a narrow slit or a sharp edge to obtain the detector line spread function (LSF), whose frequency transform leads to the MTF. In this work is presented a study of the measurement of the limiting spatial resolution using the MTF method and the line-pair bar-pattern method. Our aim is to compare the bar-pattern method with the MTF method and then evaluate what method is the best for the dairy quality control tests and when is better to perform one test or other. These acquisition procedures were tested according to its reproducibility and variation due to noise. (author)

  20. Formulation of the moiré patterns formed by superimposing of gratings consisting topological defects: moiré technique as a tool in singular optics detections

    International Nuclear Information System (INIS)

    Rasouli, Saifollah; Yeganeh, Mohammad

    2015-01-01

    The use of moiré pattern of superimposition of linear forked gratings (LFGs) and Fresnel zone plates (ZPs) has already been reported for study of different physical effects. In spite of a considerable number of applications, there is no comprehensive formulation for this kind of moiré pattern. In this work, we introduce a new family of ZPs containing topological defects that we named defected ZP (DZP) and we present a very simple, uniform, and comprehensive formulation for the moiré pattern of superimposition of two LFGs, two DZPs, and superimposition of an LFG on a DZP, using the reciprocal vector approach. For the case of the two LFGs superimposition, we show that the resulting moiré pattern has a starlike shape or is a large-scale LFG pattern. In the case in which two DZPs are superimposed, we show that the resulting moiré pattern has three general forms: large-scale DZP pattern, starlike pattern, and large-scale LFG pattern. In the superimposition of an LFG on a DZP, in special conditions a new spiral ZP having a topological defect is produced in which its defect number related to the superimposed gratings structures. The presented formulation has potential applications in singular optics measurements. (paper)

  1. Using Routinely Collected Hospital Data for Child Maltreatment Surveillance: Issues, Methods and Patterns

    Directory of Open Access Journals (Sweden)

    Scott Debbie A

    2011-01-01

    Full Text Available Abstract Background International data on child maltreatment are largely derived from child protection agencies, and predominantly report only substantiated cases of child maltreatment. This approach underestimates the incidence of maltreatment and makes inter-jurisdictional comparisons difficult. There has been a growing recognition of the importance of health professionals in identifying, documenting and reporting suspected child maltreatment. This study aimed to describe the issues around case identification using coded morbidity data, outline methods for selecting and grouping relevant codes, and illustrate patterns of maltreatment identified. Methods A comprehensive review of the ICD-10-AM classification system was undertaken, including review of index terms, a free text search of tabular volumes, and a review of coding standards pertaining to child maltreatment coding. Identified codes were further categorised into maltreatment types including physical abuse, sexual abuse, emotional or psychological abuse, and neglect. Using these code groupings, one year of Australian hospitalisation data for children under 18 years of age was examined to quantify the proportion of patients identified and to explore the characteristics of cases assigned maltreatment-related codes. Results Less than 0.5% of children hospitalised in Australia between 2005 and 2006 had a maltreatment code assigned, almost 4% of children with a principal diagnosis of a mental and behavioural disorder and over 1% of children with an injury or poisoning as the principal diagnosis had a maltreatment code assigned. The patterns of children assigned with definitive T74 codes varied by sex and age group. For males selected as having a maltreatment-related presentation, physical abuse was most commonly coded (62.6% of maltreatment cases while for females selected as having a maltreatment-related presentation, sexual abuse was the most commonly assigned form of maltreatment (52.9% of

  2. The phase interrogation method for optical fiber sensor by analyzing the fork interference pattern

    Science.gov (United States)

    Lv, Riqing; Qiu, Liqiang; Hu, Haifeng; Meng, Lu; Zhang, Yong

    2018-02-01

    The phase interrogation method for optical fiber sensor is proposed based on the fork interference pattern between the orbital angular momentum beam and plane wave. The variation of interference pattern with phase difference between the two light beams is investigated to realize the phase interrogation. By employing principal component analysis method, the features of the interference pattern can be extracted. Moreover, the experimental system is designed to verify the theoretical analysis, as well as feasibility of phase interrogation. In this work, the Mach-Zehnder interferometer was employed to convert the strain applied on sensing fiber to the phase difference between the reference and measuring paths. This interrogation method is also applicable for the measurements of other physical parameters, which can produce the phase delay in optical fiber. The performance of the system can be further improved by employing highlysensitive materials and fiber structures.

  3. Statistical Methods for Detecting and Modeling General Patterns and Relationships in Lifetime Data

    Energy Technology Data Exchange (ETDEWEB)

    Kvaloey, Jan Terje

    1999-04-01

    In this thesis, the author tries to develop methods of detecting and modeling general patterns and relationships in lifetime data. Tests with power against nonmonotonic trends and nonmonotonic co variate effects are considered, and nonparametric regression methods which allow estimation of fairly general nonlinear relationships are studied. Practical uses of some of the methods are illustrated although in a medical rather than engineering or technological context.

  4. A new method for analysing socio-ecological patterns of vulnerability

    OpenAIRE

    Kok, M.; Lüdeke, M.; Lucas, P.; Sterzel, T.; Walther, C.; Janssen, P.; Sietz, D.; de Soysa, I.

    2016-01-01

    This paper presents a method for the analysis of socio-ecological patterns of vulnerability of people being at risk of losing their livelihoods as a consequence of global environmental change. This method fills a gap in methodologies for vulnerability analysis by providing generalizations of the factors that shape vulnerability in specific socio-ecological systems and showing their spatial occurrence. The proposed method consists of four steps that include both quantitative and qualitative an...

  5. RP-HPLC Method for the Estimation of Nebivolol in Tablet Dosage Form

    Directory of Open Access Journals (Sweden)

    M. K. Sahoo

    2009-01-01

    Full Text Available A reverse phase HPLC method is described for the determination of nebivolol in tablet dosage form. Chromatography was carried on a Hypersil ODS C18 column using a mixture of methanol and water (80:20 v/v as the mobile phase at a flow rate of 1.0 mL/min with detection at 282 nm. Chlorzoxazone was used as the internal standard. The retention times were 3.175 min and 4.158 min for nebivolol and chlorzoxazone respectively. The detector response was linear in the concentration of 1-400 μg/mL. The limit of detection and limit of quantification was 0.0779 and 0.2361 μg/mL respectively. The percentage assay of nebivolol was 99.974%. The method was validated by determining its sensitivity, accuracy and precision. The proposed method is simple, fast, accurate and precise and hence can be applied for routine quality control of nebivolol in bulk and tablet dosage form.

  6. Dynamic analysis of suspension cable based on vector form intrinsic finite element method

    Science.gov (United States)

    Qin, Jian; Qiao, Liang; Wan, Jiancheng; Jiang, Ming; Xia, Yongjun

    2017-10-01

    A vector finite element method is presented for the dynamic analysis of cable structures based on the vector form intrinsic finite element (VFIFE) and mechanical properties of suspension cable. Firstly, the suspension cable is discretized into different elements by space points, the mass and external forces of suspension cable are transformed into space points. The structural form of cable is described by the space points at different time. The equations of motion for the space points are established according to the Newton’s second law. Then, the element internal forces between the space points are derived from the flexible truss structure. Finally, the motion equations of space points are solved by the central difference method with reasonable time integration step. The tangential tension of the bearing rope in a test ropeway with the moving concentrated loads is calculated and compared with the experimental data. The results show that the tangential tension of suspension cable with moving loads is consistent with the experimental data. This method has high calculated precision and meets the requirements of engineering application.

  7. Deforming black hole and cosmological solutions by quasiperiodic and/or pattern forming structures in modified and Einstein gravity

    Science.gov (United States)

    Bubuianu, Laurenţiu; Vacaru, Sergiu I.

    2018-05-01

    We elaborate on the anholonomic frame deformation method, AFDM, for constructing exact solutions with quasiperiodic structure in modified gravity theories, MGTs, and general relativity, GR. Such solutions are described by generic off-diagonal metrics, nonlinear and linear connections and (effective) matter sources with coefficients depending on all spacetime coordinates via corresponding classes of generation and integration functions and (effective) matter sources. There are studied effective free energy functionals and nonlinear evolution equations for generating off-diagonal quasiperiodic deformations of black hole and/or homogeneous cosmological metrics. The physical data for such functionals are stated by different values of constants and prescribed symmetries for defining quasiperiodic structures at cosmological scales, or astrophysical objects in nontrivial gravitational backgrounds some similar forms as in condensed matter physics. It is shown how quasiperiodic structures determined by general nonlinear, or additive, functionals for generating functions and (effective) sources may transform black hole like configurations into cosmological metrics and inversely. We speculate on possible implications of quasiperiodic solutions in dark energy and dark matter physics. Finally, it is concluded that geometric methods for constructing exact solutions consist an important alternative tool to numerical relativity for investigating nonlinear effects in astrophysics and cosmology.

  8. Stability Indicating LC-Method for Estimation of Paracetamol and Lornoxicam in Combined Dosage Form

    OpenAIRE

    Shah, Dimal A.; Patel, Neel J.; Baldania, Sunil L.; Chhalotiya, Usman K.; Bhatt, Kashyap K.

    2011-01-01

    A simple, specific and stability indicating reversed phase high performance liquid chromatographic method was developed for the simultaneous determination of paracetamol and lornoxicam in tablet dosage form. A Brownlee C-18, 5 μm column having 250×4.6 mm i.d. in isocratic mode, with mobile phase containing 0.05 M potassium dihydrogen phosphate:methanol (40:60, v/v) was used. The flow rate was 1.0 ml/min and effluents were monitored at 266 nm. The retention times of paracetamol and lornoxicam ...

  9. Analytical Method Development and Validation of Solifenacin in Pharmaceutical Dosage Forms by RP-HPLC

    OpenAIRE

    Shaik, Rihana Parveen; Puttagunta, Srinivasa Babu; Kothapalli Bannoth, Chandrasekar; Challa, Bala Sekhara Reddy

    2014-01-01

    A new, accurate, precise, and robust HPLC method was developed and validated for the determination of solifenacin in tablet dosage form. The chromatographic separation was achieved on an Inertsil ODS 3V C18 (150 mm × 4.6 mm, 5 μm) stationary phase maintained at ambient temperature with a mobile phase combination of monobasic potassium phosphate (pH 3.5) containing 0.1% triethylamine and methanol (gradient mode) at a flow rate of 1.5 mL/min, and the detection was carried out by using UV detect...

  10. Estimation of pattern shape based on CD-SEM image by using MPPC method

    Science.gov (United States)

    Onozuka, T.; Ojima, Y.; Meessen, J.; Rijpers, B.

    2006-03-01

    This study demonstrates the MPPC (Multiple Parameters Profile Characterization) measurement method utilizing ArF photo resist patterns. MPPC is a technique for estimating the three dimensional profile of patterns which are imaged and measured on the CD-SEM (critical dimension scanning electron microscope). MPPC utilizes the secondary electron signal to calculate several indices including top CD, peak CD, top rounding, bottom footing, etc. This primary focused of this study is to understand the variations in pattern profile caused by changes in exposure condition. The results demonstrate the ability to extract pattern profile shape information by MPPC measurement that could not otherwise be detected by a conventional bottom CD measurement method. Furthermore, the results were compared to cross sectional images collected by STEM (scanning transmission electron microscope) to verify the accuracy of the MPPC technique. The peak CD results accurately estimate the pattern width when the sidewall angle of the feature is nearly vertical. Additionally, line edge roughness (LER) caused by pattern profile variations was evaluated utilizing MPPC. The results suggest that MPPC may be utilized to evaluate the roughness over the entire profile.

  11. Printing, folding and assembly methods for forming 3D mesostructures in advanced materials

    Science.gov (United States)

    Zhang, Yihui; Zhang, Fan; Yan, Zheng; Ma, Qiang; Li, Xiuling; Huang, Yonggang; Rogers, John A.

    2017-03-01

    A rapidly expanding area of research in materials science involves the development of routes to complex 3D structures with feature sizes in the mesoscopic range (that is, between tens of nanometres and hundreds of micrometres). A goal is to establish methods for controlling the properties of materials systems and the function of devices constructed with them, not only through chemistry and morphology, but also through 3D architectures. The resulting systems, sometimes referred to as metamaterials, offer engineered behaviours with optical, thermal, acoustic, mechanical and electronic properties that do not occur in the natural world. Impressive advances in 3D printing techniques represent some of the most broadly recognized developments in this field, but recent successes with strategies based on concepts in origami, kirigami and deterministic assembly provide additional, unique options in 3D design and high-performance materials. In this Review, we highlight the latest progress and trends in methods for fabricating 3D mesostructures, beginning with the development of advanced material inks for nozzle-based approaches to 3D printing and new schemes for 3D optical patterning. In subsequent sections, we summarize more recent methods based on folding, rolling and mechanical assembly, including their application with materials such as designer hydrogels, monocrystalline inorganic semiconductors and graphene.

  12. Validation of HPLC and UV spectrophotometric methods for the determination of meropenem in pharmaceutical dosage form.

    Science.gov (United States)

    Mendez, Andreas S L; Steppe, Martin; Schapoval, Elfrides E S

    2003-12-04

    A high-performance liquid chromatographic method and a UV spectrophotometric method for the quantitative determination of meropenem, a highly active carbapenem antibiotic, in powder for injection were developed in present work. The parameters linearity, precision, accuracy, specificity, robustness, limit of detection and limit of quantitation were studied according to International Conference on Harmonization guidelines. Chromatography was carried out by reversed-phase technique on an RP-18 column with a mobile phase composed of 30 mM monobasic phosphate buffer and acetonitrile (90:10; v/v), adjusted to pH 3.0 with orthophosphoric acid. The UV spectrophotometric method was performed at 298 nm. The samples were prepared in water and the stability of meropenem in aqueous solution at 4 and 25 degrees C was studied. The results were satisfactory with good stability after 24 h at 4 degrees C. Statistical analysis by Student's t-test showed no significant difference between the results obtained by the two methods. The proposed methods are highly sensitive, precise and accurate and can be used for the reliable quantitation of meropenem in pharmaceutical dosage form.

  13. A validated stability-indicating UPLC method for desloratadine and its impurities in pharmaceutical dosage forms.

    Science.gov (United States)

    Rao, Dantu Durga; Satyanarayana, N V; Malleswara Reddy, A; Sait, Shakil S; Chakole, Dinesh; Mukkanti, K

    2010-02-05

    A novel stability-indicating gradient reverse phase ultra-performance liquid chromatographic (RP-UPLC) method was developed for the determination of purity of desloratadine in presence of its impurities and forced degradation products. The method was developed using Waters Aquity BEH C18 column with mobile phase containing a gradient mixture of solvents A and B. The eluted compounds were monitored at 280nm. The run time was 8min within which desloratadine and its five impurities were well separated. Desloratadine was subjected to the stress conditions of oxidative, acid, base, hydrolytic, thermal and photolytic degradation. Desloratadine was found to degrade significantly in oxidative and thermal stress conditions and stable in acid, base, hydrolytic and photolytic degradation conditions. The degradation products were well resolved from main peak and its impurities, thus proved the stability-indicating power of the method. The developed method was validated as per ICH guidelines with respect to specificity, linearity, limit of detection, limit of quantification, accuracy, precision and robustness. This method was also suitable for the assay determination of desloratadine in pharmaceutical dosage forms.

  14. Differentiation between spore-forming and asporogenic bacteria using a PCR and southern hybridization based method

    Energy Technology Data Exchange (ETDEWEB)

    Brill, J.A.; Wiegel, J. [Univ. of Georgia, Athens, GA (United States)

    1997-12-31

    A set of molecular probes was devised to develop a method for screening for the presence of sequences homologous to three representative genes exclusively involved in endosporulation. Based on known gene sequences, degenerate PCR primers were designed against spo0A and ssp. Experimental conditions were devised under which homologs of both genes were consistently detected in endospore-forming bacteria, but not in asporogenic bacteria. The PCR amplification products and dpaA/B from Bacillus subtilis were used as hybridization probes for Southern blots. Identical conditions were used with the genomic DNA from endospore-forming and asporogenic bacteria. We therefore concluded that the probes specifically detect the targeted sporulation genes and we obtained no indication that genes homologous to ssp, spo0A and dpaA/B are present in asporogenic bacteria. Thus, this assay can potentially be used to detect spore-forming bacteria in various kinds of samples and to distinguish between bacteria containing sporulation genes and those who do not regardless of whether sporulation is observed or not. 43 refs., 3 figs., 1 tab.

  15. CEMS Investigations of Fe-Silicide Phases Formed by the Method of Concentration Controlled Phase Selection

    Energy Technology Data Exchange (ETDEWEB)

    Moodley, M. K.; Bharuth-Ram, K. [University of Durban-Westville, Physics Department (South Africa); Waal, H. de; Pretorius, R. [University of Stellenbosch, Physics Department (South Africa)

    2002-03-15

    Conversion electron Moessbauer spectroscopy (CEMS) measurements have been made on Fe-silicide samples formed using the method of concentration controlled phase selection. To prepare the samples a 10 nm layer of Fe{sub 30}M{sub 70} (M=Cr, Ni) was evaporated onto Si(100) surfaces, followed by evaporation of a 60 nm Fe layer. Diffusion of the Fe into the Si substrate and the formation of different Fe-Si phases was achieved by subjecting the evaporated samples to a series of heating stages, which consisted of (a) a 10 min anneal at 800 deg. C plus etch of the residual surface layer, (b) a further 3 hr anneal at 800 deg. C, (c) a 60 mJ excimer laser anneal to an energy density of 0.8 J/cm{sup 2}, and (d) a final 3 hr anneal at 800 deg. C. CEMS measurements were used to track the Fe-silicide phases formed. The CEMS spectra consisted of doublets which, based on established hyperfine parameters, could be assigned to {alpha}- or {beta}-FeSi{sub 2} or cubic FeSi. The spectra showed that {beta}-FeSi{sub 2} had formed already at the first annealing stage. Excimer laser annealing resulted in the formation of a phase with hyperfine parameters consistent with those of {alpha}-FeSi{sub 2}. A further 3 hr anneal at 800 deg. C resulted in complete reversal to the semiconducting {beta}-FeSi{sub 2} phase.

  16. Methods of acicular ferrite forming in the weld bead metal (Brief analysis

    Directory of Open Access Journals (Sweden)

    Володимир Олександрович Лебедєв

    2016-11-01

    Full Text Available A brief analysis of the methods of acicular ferrite formation as the most preferable structural component in the weld metal has been presented. The term «acicular ferrite» is meant as a structure that forms during pearlite and martensite transformation and austenite decomposition. Acicular ferrite is a packet structure consisting of battens of bainitic ferrite, there being no cementite particles inside these battens at all. The chemical elements most effectively influencing on the formation of acicular ferrite have been considered and their combined effect as well. It has been shown in particular, that the most effective chemical element in terms of impact toughness and cost relation is manganese. Besides, the results of multipass surfacing with impulse and constant feed of low-alloy steel wire electrode have been considered. According to these results acicular ferrite forms in both cases. However, at impulse feed of the electrode wire high mechanical properties of surfacing layer were got in the first passes, the form of the acicular ferrite crystallite has been improved and volume shares of polygonal and lamellar ferrite have been reduced. An assumption has been made, according to which acicular ferrite in the surfacing layer may be obtained through superposition of mechanical low-frequency oscillation on the welding torch or on the welding pool instead of periodic thermal effect due to electrode wire periodic feed

  17. Thermal and Isothermal Methods in Development of Sustained Release Dosage Forms of Ketorolac Tromethamine

    Directory of Open Access Journals (Sweden)

    Dimple Chopra

    2008-01-01

    Full Text Available Differential scanning calorimetry (DSC is a rapid and convenient and conclusive method of screening drug-polymer blend during preformulation studies as it allows polymer incompatibility to be established instantaneously. Various batches of matrix tablets of ketorolac tromethamine (KTM with a series of compatible polymers were prepared. Batches of tablets which gave desired sustained release profile were subjected to stability testing according to ICH guidelines. The analysis for drug content was done using high performance liquid chromatography (HPLC method. The results revealed that there was no statistically significant change in drug content after storage of matrix tablets at elevated temperature of 40°C and 75% relative humidity. From our study we conclude that with careful selection of different polymers and their combinations, a stable sustained release oral dosage form of ketorolac tromethamine can be achieved.

  18. DIAGNOSTIC CHARACTERISTICS OF THE COMPUTER TESTS FORMED BY METHOD OF RESTORED FRAGMENTS

    Directory of Open Access Journals (Sweden)

    Oleksandr O. Petkov

    2013-03-01

    Full Text Available Definition of validity and reliability of tests which are formed by a method of restored fragments is considered in the article. The structure of the controlled theoretical material of limit field of knowledge, language expressions that describe the subject of control, and reliability of test, is analyzed. The technique of definition of the most important components of reliability of the considered tests is given: reliability of quantitative determination of coefficient of assimilation and technological reliability. Results of the lead pedagogical experiments have proved, that tests of the given class allow to make the control of mastering of a theoretical material over a level of reproduction in any field of knowledge with high reliability. It is shown, that validity tests with restored fragments basically caused by a degree of structurization and methodical study of a controllable material and can achieve beforehand set parameters, down to a level of absolute validity.

  19. Linking the Organizational Forms Teachers and Teaching Methods in a Class Instructional Methodology

    Directory of Open Access Journals (Sweden)

    Graciela Nápoles-Quiñones

    2016-05-01

    Full Text Available A descriptive study was conducted to show the link between the organizational forms teachers and teaching methods, to expose the pedagogical theory, to deepen the teaching-learning process through methodological class. The main content of the work of teachers is the preparation and level rise; which requires the selection and use of working methods, ways and procedures in accordance with the real and objective conditions of staff who have received the action and conducive to teaching work. Teachers should be aware that you need to master the content they teach, be aware of the level of development of its students, the specific characteristics of the group and of each student, and competent to reciprocate the content they teach with reality.

  20. Plasma spraying method for forming diamond and diamond-like coatings

    Science.gov (United States)

    Holcombe, Cressie E.; Seals, Roland D.; Price, R. Eugene

    1997-01-01

    A method and composition for the deposition of a thick layer (10) of diamond or diamond-like material. The method includes high temperature processing wherein a selected composition (12) including at least glassy carbon is heated in a direct current plasma arc device to a selected temperature above the softening point, in an inert atmosphere, and is propelled to quickly quenched on a selected substrate (20). The softened or molten composition (18) crystallizes on the substrate (20) to form a thick deposition layer (10) comprising at least a diamond or diamond-like material. The selected composition (12) includes at least glassy carbon as a primary constituent (14) and may include at least one secondary constituent (16). Preferably, the secondary constituents (16) are selected from the group consisting of at least diamond powder, boron carbide (B.sub.4 C) powder and mixtures thereof.

  1. Similar patterns of rDNA evolution in synthetic and recently formed natural populations of Tragopogon (Asteraceae allotetraploids

    Directory of Open Access Journals (Sweden)

    Soltis Pamela S

    2010-09-01

    Full Text Available Abstract Background Tragopogon mirus and T. miscellus are allotetraploids (2n = 24 that formed repeatedly during the past 80 years in eastern Washington and adjacent Idaho (USA following the introduction of the diploids T. dubius, T. porrifolius, and T. pratensis (2n = 12 from Europe. In most natural populations of T. mirus and T. miscellus, there are far fewer 35S rRNA genes (rDNA of T. dubius than there are of the other diploid parent (T. porrifolius or T. pratensis. We studied the inheritance of parental rDNA loci in allotetraploids resynthesized from diploid accessions. We investigate the dynamics and directionality of these rDNA losses, as well as the contribution of gene copy number variation in the parental diploids to rDNA variation in the derived tetraploids. Results Using Southern blot hybridization and fluorescent in situ hybridization (FISH, we analyzed copy numbers and distribution of these highly reiterated genes in seven lines of synthetic T. mirus (110 individuals and four lines of synthetic T. miscellus (71 individuals. Variation among diploid parents accounted for most of the observed gene imbalances detected in F1 hybrids but cannot explain frequent deviations from repeat additivity seen in the allotetraploid lines. Polyploid lineages involving the same diploid parents differed in rDNA genotype, indicating that conditions immediately following genome doubling are crucial for rDNA changes. About 19% of the resynthesized allotetraploid individuals had equal rDNA contributions from the diploid parents, 74% were skewed towards either T. porrifolius or T. pratensis-type units, and only 7% had more rDNA copies of T. dubius-origin compared to the other two parents. Similar genotype frequencies were observed among natural populations. Despite directional reduction of units, the additivity of 35S rDNA locus number is maintained in 82% of the synthetic lines and in all natural allotetraploids. Conclusions Uniparental reductions of

  2. Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic β-sheet forming peptide amphiphiles.

    Science.gov (United States)

    Ong, Zhan Yuin; Cheng, Junchi; Huang, Yuan; Xu, Kaijin; Ji, Zhongkang; Fan, Weimin; Yang, Yi Yan

    2014-01-01

    In the face of mounting global antibiotics resistance, the identification and development of membrane-active antimicrobial peptides (AMPs) as an alternative class of antimicrobial agent have gained significant attention. The physical perturbation and disruption of microbial membranes by the AMPs have been proposed to be an effective means to overcome conventional mechanisms of drug resistance. Recently, we have reported the design of a series of short synthetic β-sheet folding peptide amphiphiles comprised of recurring (X1Y1X2Y2)n-NH2 sequences where X: hydrophobic amino acids, Y: cationic amino acids and n: number of repeat units. In efforts to investigate the effects of key parameters including stereochemistry, chain length and sequence pattern on antimicrobial effects, systematic d-amino acid substitutions of the lead peptides (IRIK)2-NH2 (IK8-all L) and (IRVK)3-NH2 (IK12-all L) were performed. It was found that the corresponding D-enantiomers exhibited stronger antimicrobial activities with minimal or no change in hemolytic activities, hence translating very high selectivity indices of 407.0 and >9.8 for IK8-all D and IK12-all D respectively. IK8-all D was also demonstrated to be stable to degradation by broad spectrum proteases trypsin and proteinase K. The membrane disrupting bactericidal properties of IK8-all D effectively prevented drug resistance development and inhibited the growth of various clinically isolated MRSA, VRE, Acinetobacter baumanni, Pseudomonas aeruginosa, Cryptococcus. neoformans and Mycobacterium tuberculosis. Significant reduction in intracellular bacteria counts was also observed following treatment with IK8-all D in the Staphylococcus. aureus infected mouse macrophage cell line RAW264.7 (P < 0.01). These results suggest that the d-amino acids substituted β-sheet forming peptide IK8-all D with its enhanced antimicrobial activities and improved protease stability, is a promising therapeutic candidate with potential to combat

  3. Analytic Methods for Evaluating Patterns of Multiple Congenital Anomalies in Birth Defect Registries.

    Science.gov (United States)

    Agopian, A J; Evans, Jane A; Lupo, Philip J

    2018-01-15

    It is estimated that 20 to 30% of infants with birth defects have two or more birth defects. Among these infants with multiple congenital anomalies (MCA), co-occurring anomalies may represent either chance (i.e., unrelated etiologies) or pathogenically associated patterns of anomalies. While some MCA patterns have been recognized and described (e.g., known syndromes), others have not been identified or characterized. Elucidating these patterns may result in a better understanding of the etiologies of these MCAs. This article reviews the literature with regard to analytic methods that have been used to evaluate patterns of MCAs, in particular those using birth defect registry data. A popular method for MCA assessment involves a comparison of the observed to expected ratio for a given combination of MCAs, or one of several modified versions of this comparison. Other methods include use of numerical taxonomy or other clustering techniques, multiple regression analysis, and log-linear analysis. Advantages and disadvantages of these approaches, as well as specific applications, were outlined. Despite the availability of multiple analytic approaches, relatively few MCA combinations have been assessed. The availability of large birth defects registries and computing resources that allow for automated, big data strategies for prioritizing MCA patterns may provide for new avenues for better understanding co-occurrence of birth defects. Thus, the selection of an analytic approach may depend on several considerations. Birth Defects Research 110:5-11, 2018. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  4. Spatial pattern of Amazonian timber species using cartesian and spatial coordinates method

    Directory of Open Access Journals (Sweden)

    Tiago Monteiro Condé

    2016-06-01

    Full Text Available Geographic information system (GIS applied to forest analysis permit the recognition and analysis of spatial patterns of species in two and three dimensional. The aim of this study to demonstrate the efficiency of cartesian and spatial coordinates method (MCCE, method of correcting UTM coordinates of trees location in accordance with the location of field or Cartesian (X ,Y, combined with natural neighbor index (ANND in recognition and analysis of spatial distribution patterns of four commercial timber species in forest management in Caracaraí, Roraima State, Brazil. Simulations were performed on 9 ha, divided into 100 plots of 100 m2 each. Collected data were DBH > 10 cm, commercial and total heights, cartesian coordinates (X,Y and spatial coordinates (UTM. Random spatial patterns were observed in Eschweilera bracteosa and Manilkara huberi. The dispersed and rare spatial patterns were observed in Dinizia excelsa and Cedrelinga cateniformis. MCCE proved to be an efficient method in the recognition and analysis of spatial patterns of native species from Amazon rain forest, as forest planning becomes easier by 2D and 3D simulations.

  5. Suitable Methods in Spatial Pattern Analysis of Heterogeneous Wild Pistachio (Pistacia atlantica Desf. Woodlands in Zagros, Iran

    Directory of Open Access Journals (Sweden)

    Y. Erfanifard

    2014-12-01

    Full Text Available Spatial pattern of trees in forests reveals how trees interact with each other and their environment. Spatial structure of trees in forest ecosystems is affected by environmental heterogeneity that leads to their heterogeneous distribution. This study was aimed to investigate the appropriate methods to analyze spatial pattern of heterogeneous wild pistachio woodlands in Zagros, Iran. A 40-ha pure stand of wild pistachio trees (Pistacia atlantica Desf. was selected in Wild Pistachio Research Forest in Fars Province for this purpose. The Kolmogrov-Smirnov test of goodness-of-fit of inhomogeneous Poisson point process showed that the distribution of wild pistachio trees was significantly heterogeneous (α=0.05. Inhomogeneous Ripley's K-, L-, and G-functions were applied beside their homogeneous forms. Inhomogeneous Ripley's K- and L-functions showed that wild pistachio trees were primarily clumped and dispersedly distributed thereafter, while g(r not only showed these results but also well expressed the detailed changes in spatial scale. The results of inappropriate homogeneous functions in the study area showed that all three functions expressed the primary clumping of the trees more than it was and their dispersed pattern as clumped. In general, it was concluded that inhomogeneous functions should be applied to analyze the spatial pattern of heterogeneous wild pistachio trees in the study area and it is recommended to develop g(r applications due to its more detailed information

  6. The accumulation pattern of ferruginol in the heartwood-forming Cryptomeria japonica xylem as determined by time-of-flight secondary ion mass spectrometry and quantity analysis

    Science.gov (United States)

    Kuroda, Katsushi; Fujiwara, Takeshi; Hashida, Koh; Imai, Takanori; Kushi, Masayoshi; Saito, Kaori; Fukushima, Kazuhiko

    2014-01-01

    Background and Aims Heartwood formation is a unique phenomenon of tree species. Although the accumulation of heartwood substances is a well-known feature of the process, the accumulation mechanism remains unclear. The aim of this study was to determine the accumulation process of ferruginol, a predominant heartwood substance of Cryptomeria japonica, in heartwood-forming xylem. Methods The radial accumulation pattern of ferruginol was examined from sapwood and through the intermediate wood to the heartwood by direct mapping using time-of-flight secondary ion mass spectrometry (TOF-SIMS). The data were compared with quantitative results obtained from a novel method of gas chromatography analysis using laser microdissection sampling and with water distribution obtained from cryo-scanning electron microscopy. Key Results Ferruginol initially accumulated in the middle of the intermediate wood, in the earlywood near the annual ring boundary. It accumulated throughout the entire earlywood in the inner intermediate wood, and in both the earlywood and the latewood in the heartwood. The process of ferruginol accumulation continued for more than eight annual rings. Ferruginol concentration peaked at the border between the intermediate wood and heartwood, while the concentration was less in the latewood compared wiht the earlywood in each annual ring. Ferruginol tended to accumulate around the ray parenchyma cells. In addition, at the border between the intermediate wood and heartwood, the accumulation was higher in areas without water than in areas with water. Conclusions TOF-SIMS clearly revealed ferruginol distribution at the cellular level. Ferruginol accumulation begins in the middle of intermediate wood, initially in the earlywood near the annual ring boundary, then throughout the entire earlywood, and finally across to the whole annual ring in the heartwood. The heterogeneous timing of ferruginol accumulation could be related to the distribution of ray parenchyma cells

  7. Does teaching method affect students' perceptions regarding communication patterns in pediatric dentistry? A comparison of lecture and video methods.

    Science.gov (United States)

    Kalwitzki, Matthias; Meller, Christina; Beyer, Christine

    2011-08-01

    The purpose of this study was to determine whether dental students' perceptions regarding six communication patterns for use in pediatric dentistry differed depending on whether they were taught by lecturing or by video-based teaching. Prior to the introduction of interpersonal skills in a clinical course in pediatric dentistry, four consecutive cohorts of students (n=107) in a German dental school were divided equally into two groups. Group one (n=57) was taught by video sequences and group two (n=50) by conventional lecture. Six communication patterns were presented: involvement of the child's toy(s), speaking in positive phrases, mentioning a personal aspect, recalling positive behavior of the patient, addressing fear verbally, and complimenting the patient. Immediately after the presentation, students were asked by means of a questionnaire about their assessment of and intentions regarding the clinical application of the communication patterns presented. After completion of the course, they were asked about the communication patterns that had been used. There were significant differences for three communication patterns in favor of video-based teaching (pstudents perceived differences between video-based teaching and lecturing regarding ease of use, but they did not seem to benefit from one method over the other regarding clinical application.

  8. Standard test method for static leaching of monolithic waste forms for disposal of radioactive waste

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2010-01-01

    1.1 This test method provides a measure of the chemical durability of a simulated or radioactive monolithic waste form, such as a glass, ceramic, cement (grout), or cermet, in a test solution at temperatures <100°C under low specimen surface- area-to-leachant volume (S/V) ratio conditions. 1.2 This test method can be used to characterize the dissolution or leaching behaviors of various simulated or radioactive waste forms in various leachants under the specific conditions of the test based on analysis of the test solution. Data from this test are used to calculate normalized elemental mass loss values from specimens exposed to aqueous solutions at temperatures <100°C. 1.3 The test is conducted under static conditions in a constant solution volume and at a constant temperature. The reactivity of the test specimen is determined from the amounts of components released and accumulated in the solution over the test duration. A wide range of test conditions can be used to study material behavior, includin...

  9. Method for Forming Pulp Fibre Yarns Developed by a Design-driven Process

    Directory of Open Access Journals (Sweden)

    Tiia-Maria Tenhunen

    2016-01-01

    Full Text Available A simple and inexpensive method for producing water-stable pulp fibre yarns using a deep eutectic mixture composed of choline chloride and urea (ChCl/urea was developed in this work. Deep eutectic solvents (DESs are eutectic mixtures consisting of two or more components that together have a lower melting point than the individual components. DESs have been previously studied with respect to cellulose dissolution, functionalisation, and pre-treatment. This new method uses a mixture of choline chloride and urea, which is used as a swelling and dispersing agent for the pulp fibres in the yarn-forming process. Although the pulp seemed to form a gel when dispersed in ChCl/urea, the ultrastructure of the pulp was not affected. To enable water stability, pulp fibres were crosslinked by esterification using polyacrylic acid. ChCl/urea could be easily recycled and reused by distillation. The novel process described in this study enables utilisation of pulp fibres in textile production without modification or dissolution and shortening of the textile value chain. An interdisciplinary approach was used, where potential applications were explored simultaneously with material development from process development to the early phase prototyping.

  10. A method for the quantification of model form error associated with physical systems.

    Energy Technology Data Exchange (ETDEWEB)

    Wallen, Samuel P.; Brake, Matthew Robert

    2014-03-01

    In the process of model validation, models are often declared valid when the differences between model predictions and experimental data sets are satisfactorily small. However, little consideration is given to the effectiveness of a model using parameters that deviate slightly from those that were fitted to data, such as a higher load level. Furthermore, few means exist to compare and choose between two or more models that reproduce data equally well. These issues can be addressed by analyzing model form error, which is the error associated with the differences between the physical phenomena captured by models and that of the real system. This report presents a new quantitative method for model form error analysis and applies it to data taken from experiments on tape joint bending vibrations. Two models for the tape joint system are compared, and suggestions for future improvements to the method are given. As the available data set is too small to draw any statistical conclusions, the focus of this paper is the development of a methodology that can be applied to general problems.

  11. A method of LED free-form tilted lens rapid modeling based on scheme language

    Science.gov (United States)

    Dai, Yidan

    2017-10-01

    According to nonimaging optical principle and traditional LED free-form surface lens, a new kind of LED free-form tilted lens was designed. And a method of rapid modeling based on Scheme language was proposed. The mesh division method was applied to obtain the corresponding surface configuration according to the character of the light source and the desired energy distribution on the illumination plane. Then 3D modeling software and the Scheme language programming are used to generate lens model respectively. With the help of optical simulation software, a light source with the size of 1mm*1mm*1mm in volume is used in experiment, and the lateral migration distance of illumination area is 0.5m, in which total one million rays are computed. We could acquire the simulated results of both models. The simulated output result shows that the Scheme language can prevent the model deformation problems caused by the process of the model transfer, and the degree of illumination uniformity is reached to 82%, and the offset angle is 26°. Also, the efficiency of modeling process is greatly increased by using Scheme language.

  12. Adaptive oriented PDEs filtering methods based on new controlling speed function for discontinuous optical fringe patterns

    Science.gov (United States)

    Zhou, Qiuling; Tang, Chen; Li, Biyuan; Wang, Linlin; Lei, Zhenkun; Tang, Shuwei

    2018-01-01

    The filtering of discontinuous optical fringe patterns is a challenging problem faced in this area. This paper is concerned with oriented partial differential equations (OPDEs)-based image filtering methods for discontinuous optical fringe patterns. We redefine a new controlling speed function to depend on the orientation coherence. The orientation coherence can be used to distinguish the continuous regions and the discontinuous regions, and can be calculated by utilizing fringe orientation. We introduce the new controlling speed function to the previous OPDEs and propose adaptive OPDEs filtering models. According to our proposed adaptive OPDEs filtering models, the filtering in the continuous and discontinuous regions can be selectively carried out. We demonstrate the performance of the proposed adaptive OPDEs via application to the simulated and experimental fringe patterns, and compare our methods with the previous OPDEs.

  13. A Simple RP-HPLC Method for Quantitation of Itopride HCl in Tablet Dosage Form.

    Science.gov (United States)

    Thiruvengada, Rajan Vs; Mohamed, Saleem Ts; Ramkanth, S; Alagusundaram, M; Ganaprakash, K; Madhusudhana, Chetty C

    2010-10-01

    An isocratic reversed phase high-performance liquid chromatographic method with ultraviolet detection at 220 nm has been developed for the quantification of itopride hydrochloride in tablet dosage form. The quantification was carried out using C(8) column (250 mm × 4.6 mm), 5-μm particle size SS column. The mobile phase comprised of two solvents (Solvent A: buffer 1.4 mL ortho-phosphoric acid adjusted to pH 3.0 with triethyl amine and Solvent B: acetonitrile). The ratio of Solvent A: Solvent B was 75:25 v/v. The flow rate was 1.0 mL (-1)with UV detection at 220 nm. The method has been validated and proved to be robust. The calibration curve was linear in the concentration range of 80-120% with coefficient of correlation 0.9995. The percentage recovery for itopride HCl was 100.01%. The proposed method was validated for its selectivity, linearity, accuracy, and precision. The method was found to be suitable for the quality control of itopride HCl in tablet dosage formulation.

  14. Radioactive waste immobilization in protective ceramic forms by the HIP method at high pressures

    International Nuclear Information System (INIS)

    Sayenko, S.Yu.; Kantsedal, V.P.; Tarasov, R.V.; Starchenko, V.A.; Lyubtsev, R.I.

    1993-01-01

    Intense research activities have been carried out in recent years at the Kharkov Institute of Physics and Technology (KIPT) to develop the method of hot isostatic pressing (HIP) for immobilizing radioactive (primarily, high-level) wastes. With this method, the radioactive material is immobilized in a matrix under the simultaneous action of high pressures (up to 6,000 atm) and appropriate temperatures. The process has 2 variants: (1) radioactive wastes are treated as powders of oxides resulting from calcination during chemical treatment of spent fuel. In this case the radioactive material enters into the crystalline structure of the immobilized matrix or is distributed in the matrix as a homogeneous mixture; (2) protective barrier layers are pressed on spent fuel rods or their pieces as radioactive wastes, by the HIP method (fuel rod encapsulation in a protective form). Based on numerous results from various studies, the authors suggest that various ceramic compositions should be used as protective materials. Here the authors report two trends of their investigations: (1) development of ecologically clean process equipments for radioactive waste treatment by the HIP method; (2) manufacture of promising protective ceramic compositions and investigation of their physico-mechanical properties

  15. Optimization of accelerator parameters using normal form methods on high-order transfer maps

    Energy Technology Data Exchange (ETDEWEB)

    Snopok, Pavel [Michigan State Univ., East Lansing, MI (United States)

    2007-05-01

    Methods of analysis of the dynamics of ensembles of charged particles in collider rings are developed. The following problems are posed and solved using normal form transformations and other methods of perturbative nonlinear dynamics: (1) Optimization of the Tevatron dynamics: (a) Skew quadrupole correction of the dynamics of particles in the Tevatron in the presence of the systematic skew quadrupole errors in dipoles; (b) Calculation of the nonlinear tune shift with amplitude based on the results of measurements and the linear lattice information; (2) Optimization of the Muon Collider storage ring: (a) Computation and optimization of the dynamic aperture of the Muon Collider 50 x 50 GeV storage ring using higher order correctors; (b) 750 x 750 GeV Muon Collider storage ring lattice design matching the Tevatron footprint. The normal form coordinates have a very important advantage over the particle optical coordinates: if the transformation can be carried out successfully (general restrictions for that are not much stronger than the typical restrictions imposed on the behavior of the particles in the accelerator) then the motion in the new coordinates has a very clean representation allowing to extract more information about the dynamics of particles, and they are very convenient for the purposes of visualization. All the problem formulations include the derivation of the objective functions, which are later used in the optimization process using various optimization algorithms. Algorithms used to solve the problems are specific to collider rings, and applicable to similar problems arising on other machines of the same type. The details of the long-term behavior of the systems are studied to ensure the their stability for the desired number of turns. The algorithm of the normal form transformation is of great value for such problems as it gives much extra information about the disturbing factors. In addition to the fact that the dynamics of particles is represented

  16. Spectrophotometric methods for the simultaneous estimation of ofloxacin and tinidazole in bulk and pharmaceutical dosage form

    Directory of Open Access Journals (Sweden)

    Kareti Srinivasa Rao

    2011-01-01

    Full Text Available Aim: This work deals with the simultaneous estimation of Ofloxacin (OFL and Tinidazole (TNZ in in bulk and pharmaceutical dosage form, without prior separation, by three different techniques (Simultaneous equation, Absorbance ratio method and First order derivative method. Materials and Methods: The present work was carried out on Shimadzu electron UV1800 double beam UV-Visible spectrophotometer. The absorption spectra of reference and test solutions were carried out in 1 cm matched quartz cell over the range of 200 - 400 nm. Standard gift sample of OFL and TNZ obtain from Torrent pharmaceuticals Ltd., Baddi, Himachal Pradesh. Combined OFL and TNZ tablets were purchased from local market. Methanol from Merck Ltd and distilled water are used as solvent. Results: The first method is the application of simultaneous equation. Where the linearity ranges for OFL and TNZ were 5-30 μg/ml and 10-50 μg/ml respectively. The second method is the determination of ratio of absorbance at 278nm, the maximum absorption of TNZ and isobestic wavelength 283 nm, the linearity ranges for OFL and TNZ were 5-30 μg/ml and 10-50μg/ml respectively. The third method is the first order derivative method, where the linearity ranges for OFL and TNZ were 5-30 μg/ml and 10-50 μg/ml respectively. The results of the analysis have been validated statistically and by recovery studies, where the percentage recovery was found to be 100.9±0.49 and 97.30±0.20 using the simultaneous equation method, 98±0.45 and 100.4±0.48 using the graphical absorbance ratio method and 99.10±0.40 and 84.70±0.70 using first derivative method, for OFL and TNZ respectively. Conclusions: The proposed procedures are rapid, simple, require no preliminary separation steps and can be used for routine analysis of both drugs in quality control laboratories.

  17. Level and pattern of overstory retention influence rates and forms of tree mortality in mature, coniferous forests of the Pacific Northwest, USA

    Science.gov (United States)

    Lauren S. Urgenson; Charles B. Halpern; Paul D. Anderson

    2013-01-01

    Mortality of retained trees can compromise the ecological objectives of variable-retention harvest. We used a large-scale experiment replicated at six locations in western Washington and Oregon to examine the influences of retention level (40% vs. 15% of original basal area) and its spatial pattern (aggregated vs.dispersed) on the rate and form of tree mortality for 11...

  18. MODELING OF PATTERN FORMING PROCESS OF AUTOMATIC RADIO DIRECTION FINDER OF PHASE VHF IN THE DEVELOPMENT ENVIRONMENT OF LabVIEW APPLIED PROGRAMS

    Directory of Open Access Journals (Sweden)

    G. K. Aslanov

    2015-01-01

    Full Text Available In the article is developed the model demonstrating the forming process of pattern of antenna system of aerodrome quasidopler automatic radiodirection-finder station in the development environment of LabVIEW applied programs of National Instrument company. 

  19. Pilling evaluation of patterned fabrics based on a gradient field method

    Czech Academy of Sciences Publication Activity Database

    Techniková, L.; Tunák, M.; Janáček, Jiří

    2016-01-01

    Roč. 41, č. 1 (2016), s. 97-101 ISSN 0971-0426 Institutional support: RVO:67985823 Keywords : 3D surface reconstruction * fabric pilling * gradient field method * patterned fabric * pills detection Subject RIV: JS - Reliability ; Quality Management, Testing Impact factor: 0.430, year: 2016

  20. Novel method for chemical modification and patterning of the SU-8 photoresist

    DEFF Research Database (Denmark)

    Blagoi, Gabriela; Keller, Stephan Urs; Boisen, Anja

    2007-01-01

    the wetting behaviour of SU-8. The resolution limit of the AQ photopatterning method was 20 μm when using an uncollimated light source. AQ modification followed by a reaction with amino groups of Alexa-647 cadaverine and a Biotin-amino derivative proved possible modification and patterning of polymeric...

  1. Ultra-low power thin film transistors with gate oxide formed by nitric acid oxidation method

    International Nuclear Information System (INIS)

    Kobayashi, H.; Kim, W. B.; Matsumoto, T.

    2011-01-01

    We have developed a low temperature fabrication method of SiO 2 /Si structure by use of nitric acid, i.e., nitric acid oxidation of Si (NAOS) method, and applied it to thin film transistors (TFT). A silicon dioxide (SiO 2 ) layer formed by the NAOS method at room temperature possesses 1.8 nm thickness, and its leakage current density is as low as that of thermally grown SiO 2 layer with the same thickness formed at ∼900 deg C. The fabricated TFTs possess an ultra-thin NAOS SiO 2 /CVD SiO 2 stack gate dielectric structure. The ultrathin NAOS SiO 2 layer effectively blocks a gate leakage current, and thus, the thickness of the gate oxide layer can be decreased from 80 to 20 nm. The thin gate oxide layer enables to decrease the operation voltage to 2 V (cf. the conventional operation voltage of TFTs with 80 nm gate oxide: 12 V) because of the low threshold voltages, i.e., -0.5 V for P-ch TFTs and 0.5 V for N-ch TFTs, and thus the consumed power decreases to 1/36 of that of the conventional TFTs. The drain current increases rapidly with the gate voltage, and the sub-threshold voltage is ∼80 mV/dec. The low sub-threshold swing is attributable to the thin gate oxide thickness and low interface state density of the NAOS SiO 2 layer. (authors)

  2. Method of changing the control rod pattern in BWR type reactors

    International Nuclear Information System (INIS)

    Yoshida, Kenji.

    1984-01-01

    Purpose: To enable to change the control rod pattern in a short time with ease, as well as improve the availability factor of the reactor. Method: Control rods other than those being inserted into the reactor core are inserted into the reactor core to reduce the power by the reduction in the reactor core flow rate. Then, the control rod to be operated is operated partially for the change of the control rod pattern to restrict the linear heat rating of the fuels to less than 0.1 kW/ft per one hour to change the control pattern to the aimed control rod pattern. Then, the reactor core flow rate is increased after the pattern exchange for the control rod to increase the power. Since only the control rod operation is performed without adjusting the reactor core flow rate upon change of the control rod pattern, procedures can be made simply in a short time to thereby improve the availability factor of the reactor. (Moriyama, K.)

  3. Chip-scale pattern modification method for equalizing residual layer thickness in nanoimprint lithography

    Science.gov (United States)

    Youn, Sung-Won; Suzuki, Kenta; Hiroshima, Hiroshi

    2018-06-01

    A software program for modifying a mold design to obtain a uniform residual layer thickness (RLT) distribution has been developed and its validity was verified by UV-nanoimprint lithography (UV-NIL) simulation. First, the effects of granularity (G) on both residual layer uniformity and filling characteristics were characterized. For a constant complementary pattern depth and a granularity that was sufficiently larger than the minimum pattern width, filling time decreased with the decrease in granularity. For a pattern design with a wide density range and an irregular distribution, the choice of a small granularity was not always a good strategy since the etching depth required for a complementary pattern occasionally exceptionally increased with the decrease in granularity. On basis of the results obtained, the automated method was applied to a chip-scale pattern modification. Simulation results showed a marked improvement in residual layer thickness uniformity for a capacity-equalized (CE) mold. For the given conditions, the standard deviation of RLT decreased in the range from 1/3 to 1/5 in accordance with pattern designs.

  4. A study of flow patterns for staggered cylinders at low Reynolds number by spectral element method

    Energy Technology Data Exchange (ETDEWEB)

    Hsu, Li-Chieh; Chen, Chien-Lin; Ye, Jian-Zhi [National Yunlin University of Science and Technology, Taiwan (China)

    2017-06-15

    This study investigates the pattern of flow past two staggered array cylinders using the spectral element method by varying the distance between the cylinders and the angle of incidence (α) at low Reynolds numbers (Re = 100-800). Six flow patterns are identified as Shear layer reattachment (SLR), Induced separation (IS), Vortex impingement (VI), Synchronized vortex shedding (SVS), Vortex pairing and enveloping (VPE), and Vortex pairing splitting and enveloping (VPSE). These flow patterns can be transformed from one to another by changing the distance between the cylinders, the angle of incidence, or Re. SLR, IS and VI flow patterns appear in regimes with small angles of incidence (i.e., α ≤ 30° ) and hold only a single von Karman vortex shedding in a wake with one shedding frequency. SVS, VPE and VPSE flow patterns appear in regimes with large angles of incidence (i.e., 30° ≤ α ≤ 50° ) and present two synchronized von Karman vortices. Quantitative analyses and physical interpretation are also conducted to determine the generation mechanisms of the said flow patterns.

  5. [Methods of a posteriori identification of food patterns in Brazilian children: a systematic review].

    Science.gov (United States)

    Carvalho, Carolina Abreu de; Fonsêca, Poliana Cristina de Almeida; Nobre, Luciana Neri; Priore, Silvia Eloiza; Franceschini, Sylvia do Carmo Castro

    2016-01-01

    The objective of this study is to provide guidance for identifying dietary patterns using the a posteriori approach, and analyze the methodological aspects of the studies conducted in Brazil that identified the dietary patterns of children. Articles were selected from the Latin American and Caribbean Literature on Health Sciences, Scientific Electronic Library Online and Pubmed databases. The key words were: Dietary pattern; Food pattern; Principal Components Analysis; Factor analysis; Cluster analysis; Reduced rank regression. We included studies that identified dietary patterns of children using the a posteriori approach. Seven studies published between 2007 and 2014 were selected, six of which were cross-sectional and one cohort, Five studies used the food frequency questionnaire for dietary assessment; one used a 24-hour dietary recall and the other a food list. The method of exploratory approach used in most publications was principal components factor analysis, followed by cluster analysis. The sample size of the studies ranged from 232 to 4231, the values of the Kaiser-Meyer-Olkin test from 0.524 to 0.873, and Cronbach's alpha from 0.51 to 0.69. Few Brazilian studies identified dietary patterns of children using the a posteriori approach and principal components factor analysis was the technique most used.

  6. Evaluation of Two Statistical Methods Provides Insights into the Complex Patterns of Alternative Polyadenylation Site Switching

    Science.gov (United States)

    Li, Jie; Li, Rui; You, Leiming; Xu, Anlong; Fu, Yonggui; Huang, Shengfeng

    2015-01-01

    Switching between different alternative polyadenylation (APA) sites plays an important role in the fine tuning of gene expression. New technologies for the execution of 3’-end enriched RNA-seq allow genome-wide detection of the genes that exhibit significant APA site switching between different samples. Here, we show that the independence test gives better results than the linear trend test in detecting APA site-switching events. Further examination suggests that the discrepancy between these two statistical methods arises from complex APA site-switching events that cannot be represented by a simple change of average 3’-UTR length. In theory, the linear trend test is only effective in detecting these simple changes. We classify the switching events into four switching patterns: two simple patterns (3’-UTR shortening and lengthening) and two complex patterns. By comparing the results of the two statistical methods, we show that complex patterns account for 1/4 of all observed switching events that happen between normal and cancerous human breast cell lines. Because simple and complex switching patterns may convey different biological meanings, they merit separate study. We therefore propose to combine both the independence test and the linear trend test in practice. First, the independence test should be used to detect APA site switching; second, the linear trend test should be invoked to identify simple switching events; and third, those complex switching events that pass independence testing but fail linear trend testing can be identified. PMID:25875641

  7. Evaluation of Genetic Pattern of Non-Tuberculosis Mycobacterium Using VNTR Method

    Directory of Open Access Journals (Sweden)

    Noorozi J

    2011-06-01

    Full Text Available Background and Objectives: Epidemiological studies of Non-tuberculosis Mycobacterium is important because of the drug resistance pattern and worldwide dissemination of these organisms. One of genetic fingerprinting methods for epidemiological studies is VNTR (Variable Number Tandem Repeat. In this study genetic pattern of atypical Mycobacterium was evaluated by VNTR method for epidemiologic studies. Methods: 48 pulmonary and non pulmonary specimens separated from patients with the symptoms of pulmonary tuberculosis (PTB and identified as Non-tuberculosis Mycobacteriumby phenotypic and PCR-RFLP methods were selected for this study. Clinical samples and their standard strains were evaluated according to VNTR pattern using the 7 genetic loci including ETR-B. ETR-F. ETR-C. MPTR-A. ETR-A. ETR-E. ETR-D.Results: The results of VNTR method showed that none of the 7 loci had any polymorphism in the standard strains of atypical mycobacterium. Some of these variable number tandem repeat in 42 clinical samples of non-tuberculosis Mycobacterium were polymorphic while the PCR product (for any loci was not found in the remaining 6 specimens. Conclusion: Although the used genetic loci of this study were suitable for epidemiological studies of Mycobacterium tuberculosis, these loci were not able to determine the diversity of genetics of non-tuberculosis Mycobacterium Therefore, it seems necessary that other loci be studied using VNTR method.

  8. Susceptibility screening of hyphae-forming fungi with a new, easy, and fast inoculum preparation method.

    Science.gov (United States)

    Schmalreck, Arno; Willinger, Birgit; Czaika, Viktor; Fegeler, Wolfgang; Becker, Karsten; Blum, Gerhard; Lass-Flörl, Cornelia

    2012-12-01

    In vitro susceptibility testing of clinically important fungi becomes more and more essential due to the rising number of fungal infections in patients with impaired immune system. Existing standardized microbroth dilution methods for in vitro testing of molds (CLSI, EUCAST) are not intended for routine testing. These methods are very time-consuming and dependent on sporulating of hyphomycetes. In this multicentre study, a new (independent of sporulation) inoculum preparation method (containing a mixture of vegetative cells, hyphae, and conidia) was evaluated. Minimal inhibitory concentrations (MIC) of amphotericin B, posaconazole, and voriconazole of 180 molds were determined with two different culture media (YST and RPMI 1640) according to the DIN (Deutsches Institut für Normung) microdilution assay. 24 and 48 h MIC of quality control strains, tested per each test run, prepared with the new inoculum method were in the range of DIN. YST and RPMI 1640 media showed similar MIC distributions for all molds tested. MIC readings at 48 versus 24 h yield 1 log(2) higher MIC values and more than 90 % of the MICs read at 24 and 48 h were within ± 2 log(2) dilution. MIC end point reading (log(2 MIC-RPMI 1640)-log(2 MIC-YST)) of both media demonstrated a tendency to slightly lower MICs with RPMI 1640 medium. This study reports the results of a new, time-saving, and easy-to-perform method for inoculum preparation for routine susceptibility testing that can be applied for all types of spore-/non-spore and hyphae-forming fungi.

  9. CFD simulation of flow pattern in a bubble column reactor for forming aerobic granules and its development.

    Science.gov (United States)

    Fan, Wenwen; Yuan, LinJiang; Li, Yonglin

    2018-06-04

    The flow pattern is considered to play an important role in the formation of aerobic granular sludge in a bubble column reactor; therefore, it is necessary to understand the behavior of the flow in the reactor. A three-dimensional computational fluid dynamics (CFD) simulation for bubble column reactor was established to visualize the flow patterns of two-phase air-liquid flow and three-phase air-liquid-sludge flow under different ratios of height to diameter (H/D ratio) and superficial gas upflow velocities (SGVs). Moreover, a simulation of the three-phase flow pattern at the same SGV and different characteristics of the sludge was performed in this study. The results show that not only SGV but also properties of sludge involve the transformation of flow behaviors and relative velocity between liquid and sludge. For the original activated sludge floc to cultivate aerobic granules, the flow pattern has nothing to do with sludge, but is influenced by SGV, and the vortices is occurred and the relative velocity is increased with an increase in SGV; the two-phase flow can simplify the three-phase flow that predicts the flow pattern development in bubble column reactor (BCR) for aerobic granulation. For the aerobic granules, the liquid flow behavior developed from the symmetrical circular flow to numbers and small-size vortices with an increase in the sludge diameter, the relative velocity is amount up to u r =5.0, it is 29.4 times of original floc sludge.

  10. INFORMATION SUPPORT OF THE PROJECT AS A METHOD OF FORMING METASUBJECT KNOWLEDGE

    Directory of Open Access Journals (Sweden)

    И Ф Зыкова

    2016-12-01

    Full Text Available One of the fastest growing educational facilities is an online training. it is aimed at the remote receive quality knowledge in different subjects and disciplines. Given the prospects for the development of teaching aids, we have considered the possibility of its integration into the traditional school systems. In particular, we have demonstrated the implementation of this method of learning through project- based learning - students create educational materials that will be posted on the Internet.In the article the different software tools were analyzed, allowing to implement all stages of the project development with the help of cloud computing, that is, providing a collaborative and interactive way to work on the project. There are online boards for the initial stages of project development, software for management and structured storage of documents, as well as platforms that enable aesthetically and creatively presentation of the project.Given the metasubject nature of topology, the integrative component of a method of projects, we have created an online tutorial on “A method of solving mazes.” Which answers our goal - to investigate the possibility of forming metasubject knowledge by studying the topological elements in the school course.

  11. Method for distinctive estimation of stored acidity forms in acid mine wastes.

    Science.gov (United States)

    Li, Jun; Kawashima, Nobuyuki; Fan, Rong; Schumann, Russell C; Gerson, Andrea R; Smart, Roger St C

    2014-10-07

    Jarosites and schwertmannite can be formed in the unsaturated oxidation zone of sulfide-containing mine waste rock and tailings together with ferrihydrite and goethite. They are also widely found in process wastes from electrometallurgical smelting and metal bioleaching and within drained coastal lowland soils (acid-sulfate soils). These secondary minerals can temporarily store acidity and metals or remove and immobilize contaminants through adsorption, coprecipitation, or structural incorporation, but release both acidity and toxic metals at pH above about 4. Therefore, they have significant relevance to environmental mineralogy through their role in controlling pollutant concentrations and dynamics in contaminated aqueous environments. Most importantly, they have widely different acid release rates at different pHs and strongly affect drainage water acidity dynamics. A procedure for estimation of the amounts of these different forms of nonsulfide stored acidity in mining wastes is required in order to predict acid release rates at any pH. A four-step extraction procedure to quantify jarosite and schwertmannite separately with various soluble sulfate salts has been developed and validated. Corrections to acid potentials and estimation of acid release rates can be reliably based on this method.

  12. Forms And Methods Of Modern Russian Youth Involvement Into The Electoral Process

    Directory of Open Access Journals (Sweden)

    Aleksey D. Maslov

    2015-03-01

    Full Text Available In the present article authors analyzes forms and methods of modern Russian youth involvement in the electoral process. Involving young people in the electoral process is directly related to the problem of increasing the level of political culture in the society. This article presents the main forms of work to attract young people to participate in elections in our country, according to the Central Election Commission (CEC of Russia, some of the regional election commissions, the Russian Public Opinion Research Center (WCIOM. Authors note that at present there are more than one hundred and sixty legislative acts of the Russian Federation, which reflect certain aspects of the state youth policy. All these measures stimulate the political activity of young people, but in our opinion, that is not enough. The fundamental change in the attitude of young people to politics, to the institution of elections is possible only when young people feel like a real part and the subject of transformation processes in our country. In conclusion authors summarizes, that a fundamental change in the relationship of young people to politics, the institution of elections is possible only, when very young feel a real party and the subject of transformation processes in our country. This is possible only when the state is really and not formally prioritizes youth policy. Young people should have a daily state support for education, starting a business, implementation of acquired skills for a decent fee, starting a family, buying a house, etc.

  13. Aqueous sulfomethylated melamine gel-forming compositions and methods of use

    Energy Technology Data Exchange (ETDEWEB)

    Meltz, C.N.; Guetzmacher, G.D.; Chang, P.W.

    1989-04-18

    A method is described for the selective modification of the permeability of the strata of a subterranean bydrocarbon-containing reservoir consisting of introducing into a well in, communication with the reservoir; an aqueous gel-forming composition, comprising a 1.0-60.0 weight percent sulfomethylated melamine polymer solution. The solution is prepared with a 1.0 molar equivalent of a malemine, reacted with 3.0-6.7 molar equivalents of formaldehyde or a 2-6 carbon atom containing dialdehyde; 0.25-1.25 molar equivalents of an alkali metal or ammonium salt of surfurous acid; and 0.01-1.5 molar equivalents of a gel-modifying agent.

  14. Pedagogical terms of forming of healthy method of life of modern pupils

    Directory of Open Access Journals (Sweden)

    Odarchenko V.I.

    2012-10-01

    Full Text Available The questions of conditioning forming of healthy method of life of pupils of general educational educational establishments are probed. In an experiment 156 pupils took part in age from 6 to 17 years. It is set that the characteristic feature of bodily condition of health of pupils is a result of the protracted unfavorable influence of socio-economic, ecological and pedagogical factors. An idea speaks out, that search of the new going near organization of an educational educate process at school it is necessary to send educations to humanizing. It will provide creation of optimum terms for spiritual growth of personality, valuable realization of psychophysical possibilities, maintainance and strengthening of health. It is well-proven that realization of the personality oriented approach taking into account basic valeological principles positively influences on the process of education of responsible attitude toward an own health as to the greatest individual and public value.

  15. Optical characterization of Er-implanted ZnO films formed by sol-gel method

    International Nuclear Information System (INIS)

    Fukudome, T.; Kaminaka, A.; Isshiki, H.; Saito, R.; Yugo, S.; Kimura, T.

    2003-01-01

    In this paper, we report on the 1.54 μm photoluminescence (PL) of Er-implanted ZnO thin films formed by a sol-gel method on Si substrates. In spite of the polycrystalline structure of the sol-gel ZnO thin films, they showed strong PL emissions due to the near band edge recombination at 375 nm as well as the Er-related luminescence at 1.54 μm. The Er-related luminescence showed no decrease (quench) in the intensity up to the Er concentration of 1.5 x 10 21 cm -3 . The PL intensity of Er-implanted ZnO at 1.54 μm was found to be as strong as Er-doped PS (porous Si) at 20 K, and the intensity reduced to 1/3 at room temperature

  16. Method of forming a continuous polymeric skin on a cellular foam material

    Science.gov (United States)

    Duchane, David V.; Barthell, Barry L.

    1985-01-01

    Hydrophobic cellular material is coated with a thin hydrophilic polymer skin which stretches tightly over the outer surface of the foam but which does not fill the cells of the foam, thus resulting in a polymer-coated foam structure having a smoothness which was not possible in the prior art. In particular, when the hydrophobic cellular material is a specially chosen hydrophobic polymer foam and is formed into arbitrarily chosen shapes prior to the coating with hydrophilic polymer, inertial confinement fusion (ICF) targets of arbitrary shapes can be produced by subsequently coating the shapes with metal or with any other suitable material. New articles of manufacture are produced, including improved ICF targets, improved integrated circuits, and improved solar reflectors and solar collectors. In the coating method, the cell size of the hydrophobic cellular material, the viscosity of the polymer solution used to coat, and the surface tensin of the polymer solution used to coat are all very important to the coating.

  17. A DATA-MINING BASED METHOD FOR THE GAIT PATTERN ANALYSIS

    Directory of Open Access Journals (Sweden)

    Marcelo Rudek

    2015-12-01

    Full Text Available The paper presents a method developed for the gait classification based on the analysis of the trajectory of the pressure centres (CoP extracted from the contact points of the feet with the ground during walking. The data acquirement is performed ba means of a walkway with embedded tactile sensors. The proposed method includes capturing procedures, standardization of data, creation of an organized repository (data warehouse, and development of a process mining. A graphical analysis is applied to looking at the footprint signature patterns. The aim is to obtain a visual interpretation of the grouping by situating it into the normal walking patterns or deviations associated with an individual way of walking. The method consists of data classification automation which divides them into healthy and non-healthy subjects in order to assist in rehabilitation treatments for the people with related mobility problems.

  18. Simultaneous pattern recognition and track fitting by the Kalman filtering method

    International Nuclear Information System (INIS)

    Billoir, P.

    1990-01-01

    A progressive pattern recognition algorithm based on the Kalman filtering method has been tested. The algorithm starts from a small track segment or from a fitted track of a neighbouring detector, then extends the candidate tracks by adding measured points one by one. The fitted parameters and weight matrix of the candidate track are updated when adding a point, and give an increasing precision on prediction of the next point. Thus, pattern recognition and track fitting can be accomplished simultaneously. The method has been implemented and tested for track reconstruction for the vertex detector of the ZEUS experiment at DESY. Detailed procedures of the method and its performance are presented. Its flexibility is described as well. (orig.)

  19. Knowledge-Based Trajectory Error Pattern Method Applied to an Active Force Control Scheme

    Directory of Open Access Journals (Sweden)

    Endra Pitowarno, Musa Mailah, Hishamuddin Jamaluddin

    2012-08-01

    Full Text Available The active force control (AFC method is known as a robust control scheme that dramatically enhances the performance of a robot arm particularly in compensating the disturbance effects. The main task of the AFC method is to estimate the inertia matrix in the feedback loop to provide the correct (motor torque required to cancel out these disturbances. Several intelligent control schemes have already been introduced to enhance the estimation methods of acquiring the inertia matrix such as those using neural network, iterative learning and fuzzy logic. In this paper, we propose an alternative scheme called Knowledge-Based Trajectory Error Pattern Method (KBTEPM to suppress the trajectory track error of the AFC scheme. The knowledge is developed from the trajectory track error characteristic based on the previous experimental results of the crude approximation method. It produces a unique, new and desirable error pattern when a trajectory command is forced. An experimental study was performed using simulation work on the AFC scheme with KBTEPM applied to a two-planar manipulator in which a set of rule-based algorithm is derived. A number of previous AFC schemes are also reviewed as benchmark. The simulation results show that the AFC-KBTEPM scheme successfully reduces the trajectory track error significantly even in the presence of the introduced disturbances.Key Words:  Active force control, estimated inertia matrix, robot arm, trajectory error pattern, knowledge-based.

  20. The research of moisture forms in the baking yeast by the thermogravimetric analysis method

    Directory of Open Access Journals (Sweden)

    S. V. Lavrov

    2016-01-01

    Full Text Available The thermogravimetry method is one of the few absolute methods of analysis, that makes it one of the most accurate methods. In this research, thermogravimetric analysis of baking yeast (Saccharomyces cerevisiae was carried out. It allowed to identify temperature zones, which correspond to dripping with various link energy, as well as to predict operating parameters of the process of dehumidification and to choose their most effective dehydration method. The studies were conducted in the laboratory of the collective use center "Control and management of energy efficient projects" of the "Voronezh state university of engineering technologies" on the simultaneous thermal analysis device STA 449 F3 model (NETZSCH, Germany. The device records the change in a substance mass and the difference of the heat flow inside the crucible containing the sample and the crucible containing the standard analyte. The analyzer's working principle is based on continuous recording of the dependence of the material mass on time or temperature and its being heated to the selected temperature program in a specified gas atmosphere. The release or absorption of heat by the sample due to phase transitions or chemical reactions is recorded simultaneously. The study was performed in the following modes: the pressure is atmospheric, the maximum temperature is 588 K, the rate of temperature change is 5 K/min. The experiments were performed in aluminum crucibles with a total weight of 12 mg. The software NETZSCH Proteus was used for processing of the obtained TG and DTG curves. The analysis of the obtained data allowed to identify periods of water dehydration and solids transformation by thermal effect on baking yeast, and to identify temperature zones, which correspond to the release of moisture with different link form and energy.

  1. Stability Indicating Reverse Phase HPLC Method for Estimation of Rifampicin and Piperine in Pharmaceutical Dosage Form.

    Science.gov (United States)

    Shah, Umang; Patel, Shraddha; Raval, Manan

    2018-01-01

    High performance liquid chromatography is an integral analytical tool in assessing drug product stability. HPLC methods should be able to separate, detect, and quantify the various drug-related degradants that can form on storage or manufacturing, plus detect any drug-related impurities that may be introduced during synthesis. A simple, economic, selective, precise, and stability-indicating HPLC method has been developed and validated for analysis of Rifampicin (RIFA) and Piperine (PIPE) in bulk drug and in the formulation. Reversed-phase chromatography was performed on a C18 column with Buffer (Potassium Dihydrogen Orthophosphate) pH 6.5 and Acetonitrile, 30:70), (%, v/v), as mobile phase at a flow rate of 1 mL min-1. The detection was performed at 341 nm and sharp peaks were obtained for RIFA and PIPE at retention time of 3.3 ± 0.01 min and 5.9 ± 0.01 min, respectively. The detection limits were found to be 2.385 ng/ml and 0.107 ng/ml and quantification limits were found to be 7.228ng/ml and 0.325ng/ml for RIFA and PIPE, respectively. The method was validated for accuracy, precision, reproducibility, specificity, robustness, and detection and quantification limits, in accordance with ICH guidelines. Stress study was performed on RIFA and PIPE and it was found that these degraded sufficiently in all applied chemical and physical conditions. Thus, the developed RP-HPLC method was found to be suitable for the determination of both the drugs in bulk as well as stability samples of capsule containing various excipients. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  2. APPLICATION OF FORMS AND METHODS OF COMMERCIALIZATION OF INNOVATIONS THROUGH THE INTERACTION OF UNIVERSITIES AND ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Svetlana E. Sitnikova

    2018-03-01

    Full Text Available In the conditions of formation of economy based on knowledge, a key condition for successful development is the effective integration of science, education and business. Currently, the commercialization of innovation becomes a necessary factor for sustainable development of universities, one of their main tools to increase its competitiveness in the market of educational services and products. The efficiency of the process of innovation commercialization is conditioned by the rational choice of forms and methods of implementing this process. The interaction of universities and enterprises in the innovative clusters provides benefits such as effective dissemination of information about the creation of innovations, the relevant areas of research, the granting of preferences to cluster participants. The creation of technoparks suggests the presence of a specially allocated site, which houses many new businesses, so that existing institutions can only be partners of the technopark. From the point of view of commercialization of University innovation, the cluster seems to be a more attractive method compared with the creation of technology parks, but its application is necessary to adjust the approach to conducting the state policy in the field of innovation management. The interaction of universities and enterprises via an intermediary – the chamber of commerce and industry – can be described as an obstacle to the commercialization of university innovations. On the contrary, technological innovation center protects the interests of universities, rather than enterprises, as it is created to facilitate the commercialization of university innovation. Direct interaction of universities and enterprises becomes possible with the help of methods of a single transaction, a regular cooperation and a contract for the supply of innovation. The choice of methods of commercialization of innovations should be made on the basis of existing university

  3. Investigating flow patterns in a channel with complex obstacles using the lattice Boltzmann method

    Energy Technology Data Exchange (ETDEWEB)

    Yojina, Jiraporn; Ngamsaad, Waipot; Nuttavut, Narin; Triampo, Darapond; Lenbury, Yongwimon; Sriyab, Somchai; Triampo, Wannapong [Faculty of Science, Mahidol University, Bangkok (Thailand); Kanthang, Paisan [Rajamangala University of Technology, Bangkok (Thailand)

    2010-10-15

    In this work, mesoscopic modeling via a computational lattice Boltzmann method (LBM) is used to investigate the flow pattern phenomena and the physical properties of the flow field around one and two square obstacles inside a two-dimensional channel with a fixed blockage ratio,{beta} =14 , centered inside a 2D channel, for a range of Reynolds numbers (Re) from 1 to 300. The simulation results show that flow patterns can initially exhibit laminar flow at low Re and then make a transition to periodic, unsteady, and, finally, turbulent flow as the Re get higher. Streamlines and velocity profiles and a vortex shedding pattern are observed. The Strouhal numbers are calculated to characterize the shedding frequency and flow dynamics. The effect of the layouts or configurations of the obstacles are also investigated, and the possible connection between the mixing process and the appropriate design of a chemical mixing system is discussed

  4. Novel two-step method to form silk fibroin fibrous hydrogel

    International Nuclear Information System (INIS)

    Ming, Jinfa; Li, Mengmeng; Han, Yuhui; Chen, Ying; Li, Han; Zuo, Baoqi; Pan, Fukui

    2016-01-01

    Hydrogels prepared by silk fibroin solution have been studied. However, mimicking the nanofibrous structures of extracellular matrix for fabricating biomaterials remains a challenge. Here, a novel two-step method was applied to prepare fibrous hydrogels using regenerated silk fibroin solution containing nanofibrils in a range of tens to hundreds of nanometers. When the gelation process of silk solution occurred, it showed a top-down type gel within 30 min. After gelation, silk fibroin fibrous hydrogels exhibited nanofiber network morphology with β-sheet structure. Moreover, the compressive stress and modulus of fibrous hydrogels were 31.9 ± 2.6 and 2.8 ± 0.8 kPa, respectively, which was formed using 2.0 wt.% concentration solutions. In addition, fibrous hydrogels supported BMSCs attachment and proliferation over 12 days. This study provides important insight in the in vitro processing of silk fibroin into useful new materials. - Highlights: • SF fibrous hydrogel was prepared by a novel two-step method. • SF solution containing nanofibrils in a range of tens to hundreds of nanometers was prepared. • Gelation process was top-down type gel with several minutes. • SF fibrous hydrogels exhibited nanofiber network morphology with β-sheet structure. • Fibrous hydrogels had higher compressive stresses superior to porous hydrogels.

  5. Modified Inverse First Order Reliability Method (I-FORM) for Predicting Extreme Sea States.

    Energy Technology Data Exchange (ETDEWEB)

    Eckert-Gallup, Aubrey Celia; Sallaberry, Cedric Jean-Marie; Dallman, Ann Renee; Neary, Vincent Sinclair

    2014-09-01

    Environmental contours describing extreme sea states are generated as the input for numerical or physical model simulation s as a part of the stand ard current practice for designing marine structure s to survive extreme sea states. Such environmental contours are characterized by combinations of significant wave height ( ) and energy period ( ) values calculated for a given recurrence interval using a set of data based on hindcast simulations or buoy observations over a sufficient period of record. The use of the inverse first - order reliability method (IFORM) i s standard design practice for generating environmental contours. In this paper, the traditional appli cation of the IFORM to generating environmental contours representing extreme sea states is described in detail and its merits and drawbacks are assessed. The application of additional methods for analyzing sea state data including the use of principal component analysis (PCA) to create an uncorrelated representation of the data under consideration is proposed. A reexamination of the components of the IFORM application to the problem at hand including the use of new distribution fitting techniques are shown to contribute to the development of more accurate a nd reasonable representations of extreme sea states for use in survivability analysis for marine struc tures. Keywords: In verse FORM, Principal Component Analysis , Environmental Contours, Extreme Sea State Characteri zation, Wave Energy Converters

  6. Pattern Decomposition Method and a New Vegetation Index for Hyper-Multispectral Satellite Data Analysis

    Science.gov (United States)

    Muramatsu, K.; Furumi, S.; Hayashi, A.; Shiono, Y.; Ono, A.; Fujiwara, N.; Daigo, M.; Ochiai, F.

    We have developed the ``pattern decomposition method'' based on linear spectral mixing of ground objects for n-dimensional satellite data. In this method, spectral response patterns for each pixel in an image are decomposed into three components using three standard spectral shape patterns determined from the image data. Applying this method to AMSS (Airborne Multi-Spectral Scanner) data, eighteen-dimensional data are successfully transformed into three-dimensional data. Using the three components, we have developed a new vegetation index in which all the multispectral data are reflected. We consider that the index should be linear to the amount of vegetation and vegetation vigor. To validate the index, its relations to vegetation types, vegetation cover ratio, and chlorophyll contents of a leaf were studied using spectral reflectance data measured in the field with a spectrometer. The index was sensitive to vegetation types and vegetation vigor. This method and index are very useful for assessment of vegetation vigor, classifying land cover types and monitoring vegetation changes

  7. ArF photo resist pattern sample preparation method using FIB without protective coating

    Science.gov (United States)

    Okushima, Hirohisa; Onozuka, Toshihiko; Kuroda, Yasushi; Yaguchi, Toshie; Umemura, Kaoru; Tamochi, Ryuichiro; Watanabe, Kenji; Hasegawa, Norio; Kawata, Isao; Rijpers, Bart

    2006-03-01

    This paper presents a novel method of FIB (FIB: focused ion beam) sample preparation to accurately evaluate critical dimensions and profiles of ArF photo resist patterns without the use of a protective coating on the photo resist. In order to accomplish this, the FIB micro-sampling method that is one of effective FIB milling and fabrication method was employed. First a Si cap is picked up from a silicon wafer and fixed to ArF photo resist patterns to protect against ion beam irradiation. Then, a micro-sample, a piece of Si-capped ArF photo resist, was extracted from the bulk ArF photo resist. In this procedure, this silicon cap always protects ArF photo resist patterns against ion beam irradiation. For the next step, the micro-sample is fixed to a needle stub of the FIB-STEM (STEM: scanning transmission electron microscopy) compatible rotation holder. This sample on the needle stub was rotated 180 degrees and milled from the side of Si substrate. Lastly, the sample is milled to the thickness of 2μm. In this process, the ion beam is irradiating from the silicon substrate side to minimize the ion beam irradiation damages on the ArF photo resist patterns. EDX (EDX: Energy dispersive X-ray spectroscopy) analysis proved that no gallium ions were detected on the surface of the ArF photo resist patterns. The feasibility of high accelerating voltage observation of STEM to observe line edge roughness of a thick sample like 2μm without shrinkage has been demonstrated.

  8. A Twice Electrochemical-Etching Method to Fabricate Superhydrophobic-Superhydrophilic Patterns for Biomimetic Fog Harvest.

    Science.gov (United States)

    Yang, Xiaolong; Song, Jinlong; Liu, Junkai; Liu, Xin; Jin, Zhuji

    2017-08-18

    Superhydrophobic-superhydrophilic patterned surfaces have attracted more and more attention due to their great potential applications in the fog harvest process. In this work, we developed a simple and universal electrochemical-etching method to fabricate the superhydrophobic-superhydrophilic patterned surface on metal superhydrophobic substrates. The anti-electrochemical corrosion property of superhydrophobic substrates and the dependence of electrochemical etching potential on the wettability of the fabricated dimples were investigated on Al samples. Results showed that high etching potential was beneficial for efficiently producing a uniform superhydrophilic dimple. Fabrication of long-term superhydrophilic dimples on the Al superhydrophobic substrate was achieved by combining the masked electrochemical etching and boiling-water immersion methods. A long-term wedge-shaped superhydrophilic dimple array was fabricated on a superhydrophobic surface. The fog harvest test showed that the surface with a wedge-shaped pattern array had high water collection efficiency. Condensing water on the pattern was easy to converge and depart due to the internal Laplace pressure gradient of the liquid and the contact angle hysteresis contrast on the surface. The Furmidge equation was applied to explain the droplet departing mechanism and to control the departing volume. The fabrication technique and research of the fog harvest process may guide the design of new water collection devices.

  9. Transport methods: general. 8. Formulation of Transport Equation in a Split Form

    International Nuclear Information System (INIS)

    Stancic, V.

    2001-01-01

    The singular eigenfunction expansion method has enabled the application of functional analysis methods in transport theory. However, when applying it, the users were discouraged, since in most problems, including slab problems, an extra problem has occurred. It appears necessary to solve the Fredholm integral equation in order to determine the expansion coefficients. There are several reasons for this difficulty. One reason might be the use of the full-range expansion techniques even in the regions where the function is singular. Such an example is the free boundary condition that requires the distribution to be equal to zero. Moreover, at μ = 0, the transport equation becomes an integral one. Both reasons motivated us to redefine the transport equation in a more natural way. Similar to scattering theory, here we define the flux distribution as a direct sum of forward- and backward-directed neutrons, e.g., μ ≥ 0 and μ < 0, respectively. As a result, the plane geometry transport equation is being split into coupled-pair equations. Further, using an appropriate transformation, this pair of equations reduces to a self-adjoint one having the same form as the known full-range single flux. It is interesting that all the methods of full-range theory are applicable here provided the flux as well as the transformed transport operator are two-dimensional matrices. Applying this to the slab problem, we find explicit expressions for reflected and transmitted particles caused by an arbitrary plane source. That is the news in this paper. Because of space constraints, only fundamentals of this approach will be presented here. We assume that the reader is familiar with this field; therefore, the applications are noted only at the end. (author)

  10. A comparison of heuristic and model-based clustering methods for dietary pattern analysis.

    Science.gov (United States)

    Greve, Benjamin; Pigeot, Iris; Huybrechts, Inge; Pala, Valeria; Börnhorst, Claudia

    2016-02-01

    Cluster analysis is widely applied to identify dietary patterns. A new method based on Gaussian mixture models (GMM) seems to be more flexible compared with the commonly applied k-means and Ward's method. In the present paper, these clustering approaches are compared to find the most appropriate one for clustering dietary data. The clustering methods were applied to simulated data sets with different cluster structures to compare their performance knowing the true cluster membership of observations. Furthermore, the three methods were applied to FFQ data assessed in 1791 children participating in the IDEFICS (Identification and Prevention of Dietary- and Lifestyle-Induced Health Effects in Children and Infants) Study to explore their performance in practice. The GMM outperformed the other methods in the simulation study in 72 % up to 100 % of cases, depending on the simulated cluster structure. Comparing the computationally less complex k-means and Ward's methods, the performance of k-means was better in 64-100 % of cases. Applied to real data, all methods identified three similar dietary patterns which may be roughly characterized as a 'non-processed' cluster with a high consumption of fruits, vegetables and wholemeal bread, a 'balanced' cluster with only slight preferences of single foods and a 'junk food' cluster. The simulation study suggests that clustering via GMM should be preferred due to its higher flexibility regarding cluster volume, shape and orientation. The k-means seems to be a good alternative, being easier to use while giving similar results when applied to real data.

  11. A novel vector-based method for exclusive overexpression of star-form microRNAs.

    Directory of Open Access Journals (Sweden)

    Bo Qu

    Full Text Available The roles of microRNAs (miRNAs as important regulators of gene expression have been studied intensively. Although most of these investigations have involved the highly expressed form of the two mature miRNA species, increasing evidence points to essential roles for star-form microRNAs (miRNA*, which are usually expressed at much lower levels. Owing to the nature of miRNA biogenesis, it is challenging to use plasmids containing miRNA coding sequences for gain-of-function experiments concerning the roles of microRNA* species. Synthetic microRNA mimics could introduce specific miRNA* species into cells, but this transient overexpression system has many shortcomings. Here, we report that specific miRNA* species can be overexpressed by introducing artificially designed stem-loop sequences into short hairpin RNA (shRNA overexpression vectors. By our prototypic plasmid, designed to overexpress hsa-miR-146b-3p, we successfully expressed high levels of hsa-miR-146b-3p without detectable change of hsa-miR-146b-5p. Functional analysis involving luciferase reporter assays showed that, like natural miRNAs, the overexpressed hsa-miR-146b-3p inhibited target gene expression by 3'UTR seed pairing. Our demonstration that this method could overexpress two other miRNAs suggests that the approach should be broadly applicable. Our novel strategy opens the way for exclusively stable overexpression of miRNA* species and analyzing their unique functions both in vitro and in vivo.

  12. Altered cleavage patterns in human tripronuclear embryos and their association to fertilization method

    DEFF Research Database (Denmark)

    Joergensen, Mette Warming; Agerholm, Inge; Hindkjaer, Johnny

    2014-01-01

    PURPOSE: To analyze the cleavage patterns in dipronuclear (2PN) and tripronuclear (3PN) embryos in relation to fertilization method. METHOD: Time-lapse analysis. RESULTS: Compared to 2PN, more 3PN IVF embryos displayed early cleavage into 3 cells (p ... stage (p embryos, the 2nd and 3rd cleavage cycles were completed within the expected time frame. However, timing of the cell divisions within the cleavage cycles differed between the two groups. In contrast......, the completion of the 1st, 2nd, and 3rd cleavage cycle was delayed, but with a similar division pattern for 3PN ICSI compared with the 2PN ICSI embryos. 3PN, more often than 2PN ICSI embryos, displayed early cleavage into 3 cells (p = 0.03) and arrested development from the compaction stage and onwards (p = 0...

  13. Methods for shifting the pattern of energy deposition with a MAPA

    International Nuclear Information System (INIS)

    Guerquin-Kern, J.L.; Hagmann, M.J.; Levin, R.L.

    1987-01-01

    In earlier work the authors observed local heating in bone when an amputated human leg was treated with a MAPA. For this reason we have experimentally compared several methods for controlling the pattern of energy deposition. These methods include radial displacement of the phantom relative to the MAPA, adjusting phase and magnitude of the currents in the dipole elements, and the use of dielectric spacers between the bolus and parts of the phantom. Cylindrical homogeneous muscle-phantoms have been used in these tests. Both theory and experiments show that greater displacement of the pattern can be obtained using phase-shifting than is possible with radial displacement of the phantom. Dielectric spacers act as a shield by decoupling the phantom from the MAPA. The dielectric spacers are simple to use and give results that are stable and easy to predict

  14. Method of thermally processing superplastically formed aluminum-lithium alloys to obtain optimum strengthening

    Science.gov (United States)

    Anton, Claire E. (Inventor)

    1993-01-01

    Optimum strengthening of a superplastically formed aluminum-lithium alloy structure is achieved via a thermal processing technique which eliminates the conventional step of solution heat-treating immediately following the step of superplastic forming of the structure. The thermal processing technique involves quenching of the superplastically formed structure using static air, forced air or water quenching.

  15. Beam angle optimization for intensity-modulated radiation therapy using a guided pattern search method

    International Nuclear Information System (INIS)

    Rocha, Humberto; Dias, Joana M; Ferreira, Brígida C; Lopes, Maria C

    2013-01-01

    Generally, the inverse planning of radiation therapy consists mainly of the fluence optimization. The beam angle optimization (BAO) in intensity-modulated radiation therapy (IMRT) consists of selecting appropriate radiation incidence directions and may influence the quality of the IMRT plans, both to enhance better organ sparing and to improve tumor coverage. However, in clinical practice, most of the time, beam directions continue to be manually selected by the treatment planner without objective and rigorous criteria. The goal of this paper is to introduce a novel approach that uses beam’s-eye-view dose ray tracing metrics within a pattern search method framework in the optimization of the highly non-convex BAO problem. Pattern search methods are derivative-free optimization methods that require a few function evaluations to progress and converge and have the ability to better avoid local entrapment. The pattern search method framework is composed of a search step and a poll step at each iteration. The poll step performs a local search in a mesh neighborhood and ensures the convergence to a local minimizer or stationary point. The search step provides the flexibility for a global search since it allows searches away from the neighborhood of the current iterate. Beam’s-eye-view dose metrics assign a score to each radiation beam direction and can be used within the pattern search framework furnishing a priori knowledge of the problem so that directions with larger dosimetric scores are tested first. A set of clinical cases of head-and-neck tumors treated at the Portuguese Institute of Oncology of Coimbra is used to discuss the potential of this approach in the optimization of the BAO problem. (paper)

  16. Investigation of CoPd alloys by XPS and EPES using the pattern recognition method

    Czech Academy of Sciences Publication Activity Database

    Lesiak, B.; Zemek, Josef; Jiříček, Petr; Jozwik, A.

    2007-01-01

    Roč. 428, - (2007), s. 190-196 ISSN 0925-8388 R&D Projects: GA ČR GA202/06/0459 Institutional research plan: CEZ:AV0Z10100521 Keywords : CoPd alloys * x-ray photoelectron spectroscopy (XPS) * elastic peak electron spectroscopy (EPES) * pattern recognition method * fuzzy k-nearest neighbour rule (fkNN) * quantitative analysis * surface segregation Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.455, year: 2007

  17. Application of Classification Methods for Forecasting Mid-Term Power Load Patterns

    Science.gov (United States)

    Piao, Minghao; Lee, Heon Gyu; Park, Jin Hyoung; Ryu, Keun Ho

    Currently an automated methodology based on data mining techniques is presented for the prediction of customer load patterns in long duration load profiles. The proposed approach in this paper consists of three stages: (i) data preprocessing: noise or outlier is removed and the continuous attribute-valued features are transformed to discrete values, (ii) cluster analysis: k-means clustering is used to create load pattern classes and the representative load profiles for each class and (iii) classification: we evaluated several supervised learning methods in order to select a suitable prediction method. According to the proposed methodology, power load measured from AMR (automatic meter reading) system, as well as customer indexes, were used as inputs for clustering. The output of clustering was the classification of representative load profiles (or classes). In order to evaluate the result of forecasting load patterns, the several classification methods were applied on a set of high voltage customers of the Korea power system and derived class labels from clustering and other features are used as input to produce classifiers. Lastly, the result of our experiments was presented.

  18. An Advanced Electrospinning Method of Fabricating Nanofibrous Patterned Architectures with Controlled Deposition and Desired Alignment

    Science.gov (United States)

    Rasel, Sheikh Md

    We introduce a versatile advanced method of electrospinning for fabricating various kinds of nanofibrous patterns along with desired alignment, controlled amount of deposition and locally variable density into the architectures. In this method, we employed multiple electrodes whose potentials have been altered in milliseconds with the help of microprocessor based control system. Therefore, key success of this method was that the electrical field as well as charge carrying fibers could be switched shortly from one electrode's location to another, as a result, electrospun fibers could be deposited on the designated areas with desired alignment. A wide range of nanofibrous patterned architectures were constructed using proper arrangement of multiple electrodes. By controlling the concurrent activation time of two adjacent electrodes, we demonstrated that amount of fibers going into the pattern can be adjusted and desired alignment in electrospun fibers can be obtained. We also revealed that the deposition density of electrospun fibers in different areas of patterned architectures can be varied. We showed that by controlling the deposition time between two adjacent electrodes, a number of functionally graded patterns can be generated with uniaxial alignment. We also demonstrated that this handy method was capable of producing random, aligned, and multidirectional nanofibrous mats by engaging a number of electrodes and switching them in desired patterns. A comprehensive study using finite element method was carried out to understand the effects of electrical field. Simulation results revealed that electrical field strength alters shortly based on electrode control switch patterns. Nanofibrous polyvinyl alcohol (PVA) scaffolds and its composite reinforced with wollastonite and wood flour were fabricated using rotating drum electrospinning technique. Morphological, mechanical, and thermal, properties were characterized on PVA/wollastonite and PVA/wood flour nanocomposites

  19. Characterizing Dynamic Walking Patterns and Detecting Falls with Wearable Sensors Using Gaussian Process Methods

    Directory of Open Access Journals (Sweden)

    Taehwan Kim

    2017-05-01

    Full Text Available By incorporating a growing number of sensors and adopting machine learning technologies, wearable devices have recently become a prominent health care application domain. Among the related research topics in this field, one of the most important issues is detecting falls while walking. Since such falls may lead to serious injuries, automatically and promptly detecting them during daily use of smartphones and/or smart watches is a particular need. In this paper, we investigate the use of Gaussian process (GP methods for characterizing dynamic walking patterns and detecting falls while walking with built-in wearable sensors in smartphones and/or smartwatches. For the task of characterizing dynamic walking patterns in a low-dimensional latent feature space, we propose a novel approach called auto-encoded Gaussian process dynamical model, in which we combine a GP-based state space modeling method with a nonlinear dimensionality reduction method in a unique manner. The Gaussian process methods are fit for this task because one of the most import strengths of the Gaussian process methods is its capability of handling uncertainty in the model parameters. Also for detecting falls while walking, we propose to recycle the latent samples generated in training the auto-encoded Gaussian process dynamical model for GP-based novelty detection, which can lead to an efficient and seamless solution to the detection task. Experimental results show that the combined use of these GP-based methods can yield promising results for characterizing dynamic walking patterns and detecting falls while walking with the wearable sensors.

  20. Macron Formed Liner Compression as a Practical Method for Enabling Magneto-Inertial Fusion

    Energy Technology Data Exchange (ETDEWEB)

    Slough, John

    2011-12-10

    The entry of fusion as a viable, competitive source of power has been stymied by the challenge of finding an economical way to provide for the confinement and heating of the plasma fuel. The main impediment for current nuclear fusion concepts is the complexity and large mass associated with the confinement systems. To take advantage of the smaller scale, higher density regime of magnetic fusion, an efficient method for achieving the compressional heating required to reach fusion gain conditions must be found. The very compact, high energy density plasmoid commonly referred to as a Field Reversed Configuration (FRC) provides for an ideal target for this purpose. To make fusion with the FRC practical, an efficient method for repetitively compressing the FRC to fusion gain conditions is required. A novel approach to be explored in this endeavor is to remotely launch a converging array of small macro-particles (macrons) that merge and form a more massive liner inside the reactor which then radially compresses and heats the FRC plasmoid to fusion conditions. The closed magnetic field in the target FRC plasmoid suppresses the thermal transport to the confining liner significantly lowering the imploding power needed to compress the target. With the momentum flux being delivered by an assemblage of low mass, but high velocity macrons, many of the difficulties encountered with the liner implosion power technology are eliminated. The undertaking to be described in this proposal is to evaluate the feasibility achieving fusion conditions from this simple and low cost approach to fusion. During phase I the design and testing of the key components for the creation of the macron formed liner have been successfully carried out. Detailed numerical calculations of the merging, formation and radial implosion of the Macron Formed Liner (MFL) were also performed. The phase II effort will focus on an experimental demonstration of the macron launcher at full power, and the demonstration

  1. Spectrophotometric methods for the determination of benazepril hydrochloride in its single and multi-component dosage forms.

    Science.gov (United States)

    El-Yazbi, F A; Abdine, H H; Shaalan, R A

    1999-06-01

    Three sensitive and accurate methods are presented for the determination of benazepril in its dosage forms. The first method uses derivative spectrophotometry to resolve the interference due to formulation matrix. The second method depends on the color formed by the reaction of the drug with bromocresol green (BCG). The third one utilizes the reaction of benazepril, after alkaline hydrolysis, with 3-methylbenzothialozone (MBTH) hydrazone where the produced color is measured at 593 nm. The latter method was extended to develop a stability-indicating method for this drug. Moreover, the derivative method was applied for the determination of benazepril in its combination with hydrochlorothiazide. The proposed methods were applied for the analysis of benazepril in the pure form and in tablets. The coefficient of variation was less than 2%.

  2. Substantion of Choosing the Method of Surgical Treatment of Complicated Forms of Chronic Pancreatitis

    Directory of Open Access Journals (Sweden)

    I.Ya. Budzak

    2013-04-01

    Full Text Available In the Institute’s clinic during 2010–2012, 43 patients were operated for complicated forms of chronic pancreatitis. Based on the data of computed tomography and endoscopic retrograde cholangiopancreatography, the variants of pathology of the pancreas, which are significant for the selection of operation method, were chosen. Evaluation of intraoperative biopsies showed that the main manifestation of chronic pancreatitis in all cases was evident fibrosis of gland tissue. In this evaluation, in patients with III degree of fibrosis, fibrous tissue was 68.2–76.4 % of the area of pancreas, and exocrine one — 16.2–24.8 %, in patients with IV degree of fibrosis, respectively 79.5–95.5 and 2.3–10.8 %. Indications for organ-preserving resection, resection-draining interventions and isolated, draining pancreatic ductal system operations have been indicated. Specific weight of combined resection-draining interventions with preservation of the duodenum was 30.2 %, the overall mortality rate — 2.3 %, duration of postoperative bed-day (9.1 ± 0.8.

  3. Obtaining tetracalcium phosphate and hydroxyapatite in powder form by wet method

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Sara Verusca de; Fook, Marcus Vinicius Lia; Araujo, Elaine Patricia; Medeiros, Keila Machado; Rabello, Guilherme Portela; Barbosa Renata; Araujo, Edcleide Maria, E-mail: saraveruscadeoliveira@yahoo.com.br, E-mail: marcusvinicius@dema.ufcg.edu.br, E-mail: elainepatriciaaraujo@yahoo.com.br, E-mail: keilamm@ig.com.br, E-mail: guilhermeportel@hotmail.com, E-mail: rrenatabarbosa@yahoo.com, E-mail: edcleide@dema.ufcg.edu.br [Universidade Federal de Campina Grande (UAEMa/CCT/UFCG), Campina Grande, PB (Brazil)

    2009-07-01

    The development of research in the area of advanced materials and tissue engineering has increased greatly in recent years found that bioceramics are outstanding in the replacement and regeneration of bone tissue, mainly formed by the calcium phosphate ceramics. The objective of this research is to obtain the calcium phosphate where Ca/P = 1.67 and 2.0, to observe the formation of phases after having subjected these materials to heat treatment. The calcium phosphate was produced by the wet method using a direct reaction of neutralization and characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and X-ray microanalysis (EDS). The XRD results confirm the presence of hydroxyapatite phase in the sample with Ca/P = 1.67, whereas the phosphates prepared with Ca/P = 2.0 ratio show a combination of hydroxyapatite and phase β- tricalcium phosphate. The micrographs obtained are characteristic of ceramic material called calcium phosphate. EDS confirmed the presence of Ca, P and O in the material. (author)

  4. Obtaining tetracalcium phosphate and hydroxyapatite in powder form by wet method

    International Nuclear Information System (INIS)

    Oliveira, Sara Verusca de; Fook, Marcus Vinicius Lia; Araujo, Elaine Patricia; Medeiros, Keila Machado; Rabello, Guilherme Portela; Barbosa Renata; Araujo, Edcleide Maria

    2009-01-01

    The development of research in the area of advanced materials and tissue engineering has increased greatly in recent years found that bioceramics are outstanding in the replacement and regeneration of bone tissue, mainly formed by the calcium phosphate ceramics. The objective of this research is to obtain the calcium phosphate where Ca/P = 1.67 and 2.0, to observe the formation of phases after having subjected these materials to heat treatment. The calcium phosphate was produced by the wet method using a direct reaction of neutralization and characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and X-ray microanalysis (EDS). The XRD results confirm the presence of hydroxyapatite phase in the sample with Ca/P = 1.67, whereas the phosphates prepared with Ca/P = 2.0 ratio show a combination of hydroxyapatite and phase β- tricalcium phosphate. The micrographs obtained are characteristic of ceramic material called calcium phosphate. EDS confirmed the presence of Ca, P and O in the material. (author)

  5. Generalized Pattern Search methods for a class of nonsmooth optimization problems with structure

    Science.gov (United States)

    Bogani, C.; Gasparo, M. G.; Papini, A.

    2009-07-01

    We propose a Generalized Pattern Search (GPS) method to solve a class of nonsmooth minimization problems, where the set of nondifferentiability is included in the union of known hyperplanes and, therefore, is highly structured. Both unconstrained and linearly constrained problems are considered. At each iteration the set of poll directions is enforced to conform to the geometry of both the nondifferentiability set and the boundary of the feasible region, near the current iterate. This is the key issue to guarantee the convergence of certain subsequences of iterates to points which satisfy first-order optimality conditions. Numerical experiments on some classical problems validate the method.

  6. Simple and efficient methods for the accurate evaluation of patterning effects in ultrafast photonic switches

    DEFF Research Database (Denmark)

    Xu, Jing; Ding, Yunhong; Peucheret, Christophe

    2011-01-01

    Although patterning effects (PEs) are known to be a limiting factor of ultrafast photonic switches based on semiconductor optical amplifiers (SOAs), a simple approach for their evaluation in numerical simulations and experiments is missing. In this work, we experimentally investigate and verify...... as well as the operation bit rate. Furthermore, a simple and effective method for probing the maximum PEs is demonstrated, which may relieve the computational effort or the experimental difficulties associated with the use of long PRBSs for the simulation or characterization of SOA-based switches. Good...... agrement with conventional PRBS characterization is obtained. The method is suitable for quick and systematic estimation and optimization of the switching performance....

  7. Separation of magnetic from non-magnetic information in the Bitter pattern method

    International Nuclear Information System (INIS)

    Szmaja, Witold

    2001-01-01

    The paper deals with the problem of separating magnetic and non-magnetic contributions to the image contrast in the Bitter pattern method. With the help of the digital image difference procedure, it is demonstrated for the first time for the Bitter method that the separation is easy to achieve for relatively soft magnetic specimens, when an external field can be applied to simply produce the non-magnetic reference image of the specimen area under study. It is also shown that obtaining satisfactory results is principally impossible when removing the colloid from the specimen surface is used for the purpose of recording the non-magnetic image

  8. A novel method to achieve selective emitter for silicon solar cell using low cost pattern-able a-Si thin films as the semi-transparent phosphorus diffusion barrier

    International Nuclear Information System (INIS)

    Chen, Da Ming; Liang, Zong Cun; Zhuang, Lin; Lin, Yang Huan; Shen, Hui

    2012-01-01

    Highlights: ► a-Si thin films as semitransparent phosphorus diffusion barriers for solar cell. ► a-Si thin films on silicon wafers were patterned by the alkaline solution. ► Selective emitter was formed with patterned a-Si as diffusion barrier for solar cell. -- Abstract: Selective emitter for silicon solar cell was realized by employing a-Si thin films as the semi-transparent diffusion barrier. The a-Si thin films with various thicknesses (∼10–40 nm) were deposited by the electron-beam evaporation technique. Emitters with sheet resistances from 37 to 145 Ω/□ were obtained via POCl 3 diffusion process. The thickness of the a-Si diffusion barrier was optimized to be 15 nm for selective emitter in our work. Homemade mask which can dissolve in ethanol was screen-printed on a-Si film to make pattern. The a-Si film was then patterned in KOH solution to form finger-like design. Selective emitter was obtainable with one-step diffusion with patterned a-Si film on. Combinations of sheet resistances for the high-/low-level doped regions of 39.8/112.1, 36.2/88.8, 35.4/73.9 were obtained. These combinations are suitable for screen-printed solar cells. This preparation method of selective emitter based on a-Si diffusion barrier is a promising approach for low cost industrial manufacturing.

  9. Forming a method mindset: The role of knowledge and preference in facilitating heuristic method usage in design

    DEFF Research Database (Denmark)

    Daalhuizen, Jaap; Person, Oscar; Gattol, Valentin

    2013-01-01

    Both systematic and heuristic methods are common practice when designing. Yet, in teaching students how to design, heuristic methods are typically only granted a secondary role. So, how do designers and students develop a mindset for using heuristic methods? In this paper, we study how prior...... knowledge (about heuristic methods and their usage) and preference (for using heuristic methods) relate to the reported use of heuristic methods when designing. Drawing on a survey among 304 students enrolled in a master-level course on design theory and methodology, we investigated method usage for five...... indirectly influenced method usage through a 'complementary' mediation of method preference....

  10. Huitzoctli: A system to design Control Rod Pattern for BWR's using a hybrid method

    International Nuclear Information System (INIS)

    Castillo, Alejandro; Ortiz-Servin, Juan Jose; Perusquia, Raul; Morales, Luis B.

    2011-01-01

    Highlights: → The system was developed to design Control Rod Patterns for Boiling Water Reactors. → The critical reactor core and the thermal limits were fulfilled in all tested cases. → The Fuel Loading Pattern remains without changes during the iterative process. → The system uses the heuristics techniques: Scatter Search and Tabu Search. → The effective multiplication factor k eff at the EOC was improved in all tested cases. - Abstract: Huitzoctli system was developed to design Control Rod Patterns for Boiling Water Reactors (BWR). The main idea is to obtain a Control Rod Pattern under the following considerations: (a) the critical reactor core state is satisfied, (b) the axial power distribution must be adjusted to a target axial power distribution proposal, and (c) the maximum Fraction of Critical Power Ratio (MFLCPR), the maximum Fraction of Linear Power Density (FLPD) and the maximum Fraction of Average Planar Power Density (MPGR) must be fulfilled. Those parameters were obtained using the 3D CM-PRESTO code. In order to decrease the problem complexity, Control Cell Core load strategy was implemented; in the same way, intermediate axial positions and core eighth symmetry were took into account. In this work, the cycle length was divided in 12 burnup steps. The Fuel Loading Pattern is an input data and it remains without changes during the iterative process. The Huitzoctli system was developed to use the combinatorial heuristics techniques Scatter Search and Tabu Search. The first one was used as a global search method and the second one as a local search method. The Control Rod Patterns obtained with the Huitzoctli system were compared to other Control Rod Patterns designs obtained with other optimization techniques, under the same operating conditions. The results show a good performance of the system. In all cases the thermal limits were satisfied, and the axial power distribution was adjusted to the target axial power distribution almost

  11. Sources and methods to reconstruct past masting patterns in European oak species.

    Science.gov (United States)

    Szabó, Péter

    2012-01-01

    The irregular occurrence of good seed years in forest trees is known in many parts of the world. Mast year frequency in the past few decades can be examined through field observational studies; however, masting patterns in the more distant past are equally important in gaining a better understanding of long-term forest ecology. Past masting patterns can be studied through the examination of historical written sources. These pose considerable challenges, because data in them were usually not recorded with the aim of providing information about masting. Several studies examined masting in the deeper past, however, authors hardly ever considered the methodological implications of using and combining various source types. This paper provides a critical overview of the types of archival written that are available for the reconstruction of past masting patterns for European oak species and proposes a method to unify and evaluate different types of data. Available sources cover approximately eight centuries and can be put into two basic categories: direct observations on the amount of acorns and references to sums of money received in exchange for access to acorns. Because archival sources are highly different in origin and quality, the optimal solution for creating databases for past masting data is a three-point scale: zero mast, moderate mast, good mast. When larger amounts of data are available in a unified three-point-scale database, they can be used to test hypotheses about past masting frequencies, the driving forces of masting or regional masting patterns.

  12. Application of hierarchical clustering method to classify of space-time rainfall patterns

    Science.gov (United States)

    Yu, Hwa-Lung; Chang, Tu-Je

    2010-05-01

    Understanding the local precipitation patterns is essential to the water resources management and flooding mitigation. The precipitation patterns can vary in space and time depending upon the factors from different spatial scales such as local topological changes and macroscopic atmospheric circulation. The spatiotemporal variation of precipitation in Taiwan is significant due to its complex terrain and its location at west pacific and subtropical area, where is the boundary between the pacific ocean and Asia continent with the complex interactions among the climatic processes. This study characterizes local-scale precipitation patterns by classifying the historical space-time precipitation records. We applied the hierarchical ascending clustering method to analyze the precipitation records from 1960 to 2008 at the six rainfall stations located in Lan-yang catchment at the northeast of the island. Our results identify the four primary space-time precipitation types which may result from distinct driving forces from the changes of atmospheric variables and topology at different space-time scales. This study also presents an important application of the statistical downscaling to combine large-scale upper-air circulation with local space-time precipitation patterns.

  13. A kinematic method for footstrike pattern detection in barefoot and shod runners.

    Science.gov (United States)

    Altman, Allison R; Davis, Irene S

    2012-02-01

    Footstrike patterns during running can be classified discretely into a rearfoot strike, midfoot strike and forefoot strike by visual observation. However, the footstrike pattern can also be classified on a continuum, ranging from 0% to 100% (extreme rearfoot to extreme forefoot) using the strike index, a measure requiring force plate data. When force data are not available, an alternative method to quantify the strike pattern must be used. The purpose of this paper was to quantify the continuum of foot strike patterns using an easily attainable kinematic measure, and compare it to the strike index measure. Force and kinematic data from twenty subjects were collected as they ran across an embedded force plate. Strike index and the footstrike angle were identified for the four running conditions of rearfoot strike, midfoot strike and forefoot strike, as well as barefoot. The footstrike angle was calculated as the angle of the foot with respect to the ground in the sagittal plane. Results indicated that the footstrike angle was significantly correlated with strike index. The linear regression model suggested that strike index can be accurately estimated, in both barefoot and shod conditions, in the absence of force data. Copyright © 2011 Elsevier B.V. All rights reserved.

  14. [Investigation on pattern and methods of quality control for Chinese materia medica based on dao-di herbs and bioassay - bioassay for Coptis chinensis].

    Science.gov (United States)

    Yan, Dan; Xiao, Xiao-he

    2011-05-01

    Establishment of bioassay methods is the technical issues to be faced with in the bioassay of Chinese materia medica. Taking the bioassay of Coptis chinensis Franch. as an example, the establishment process and application of the bioassay methods (including bio-potency and bio-activity fingerprint) were explained from the aspects of methodology, principle of selection, experimental design, method confirmation and data analysis. The common technologies were extracted and formed with the above aspects, so as to provide technical support for constructing pattern and method of the quality control for Chinese materia medica based on the dao-di herbs and bioassay.

  15. Development for 2D pattern quantification method on mask and wafer

    Science.gov (United States)

    Matsuoka, Ryoichi; Mito, Hiroaki; Toyoda, Yasutaka; Wang, Zhigang

    2010-03-01

    We have developed the effective method of mask and silicon 2-dimensional metrology. The aim of this method is evaluating the performance of the silicon corresponding to Hotspot on a mask. The method adopts a metrology management system based on DBM (Design Based Metrology). This is the high accurate contouring created by an edge detection algorithm used in mask CD-SEM and silicon CD-SEM. Currently, as semiconductor manufacture moves towards even smaller feature size, this necessitates more aggressive optical proximity correction (OPC) to drive the super-resolution technology (RET). In other words, there is a trade-off between highly precise RET and mask manufacture, and this has a big impact on the semiconductor market that centers on the mask business. 2-dimensional Shape quantification is important as optimal solution over these problems. Although 1-dimensional shape measurement has been performed by the conventional technique, 2-dimensional shape management is needed in the mass production line under the influence of RET. We developed the technique of analyzing distribution of shape edge performance as the shape management technique. On the other hand, there is roughness in the silicon shape made from a mass-production line. Moreover, there is variation in the silicon shape. For this reason, quantification of silicon shape is important, in order to estimate the performance of a pattern. In order to quantify, the same shape is equalized in two dimensions. And the method of evaluating based on the shape is popular. In this study, we conducted experiments for averaging method of the pattern (Measurement Based Contouring) as two-dimensional mask and silicon evaluation technique. That is, observation of the identical position of a mask and a silicon was considered. It is possible to analyze variability of the edge of the same position with high precision. The result proved its detection accuracy and reliability of variability on two-dimensional pattern (mask and

  16. Load Disaggregation via Pattern Recognition: A Feasibility Study of a Novel Method in Residential Building

    Directory of Open Access Journals (Sweden)

    Younghoon Kwak

    2018-04-01

    Full Text Available In response to the need to improve energy-saving processes in older buildings, especially residential ones, this paper describes the potential of a novel method of disaggregating loads in light of the load patterns of household appliances determined in residential buildings. Experiments were designed to be applicable to general residential buildings and four types of commonly used appliances were selected to verify the method. The method assumes that loads are disaggregated and measured by a single primary meter. Following the metering of household appliances and an analysis of the usage patterns of each type, values of electric current were entered into a Hidden Markov Model (HMM to formulate predictions. Thereafter, the HMM repeatedly performed to output the predicted data close to the measured data, while errors between predicted and the measured data were evaluated to determine whether they met tolerance. When the method was examined for 4 days, matching rates in accordance with the load disaggregation outcomes of the household appliances (i.e., laptop, refrigerator, TV, and microwave were 0.994, 0.992, 0.982, and 0.988, respectively. The proposed method can provide insights into how and where within such buildings energy is consumed. As a result, effective and systematic energy saving measures can be derived even in buildings in which monitoring sensors and measurement equipment are not installed.

  17. Mass-forming intrahepatic cholangiocarcinoma: Enhancement patterns in the arterial phase of dynamic hepatic CT - Correlation with clinicopathological findings

    Energy Technology Data Exchange (ETDEWEB)

    Fujita, Nobuhiro; Asayama, Yoshiki; Nishie, Akihiro; Ishigami, Kousei; Ushijima, Yasuhiro; Okamoto, Daisuke; Moirta, Koichiro; Honda, Hiroshi [Kyushu University, Department of Clinical Radiology, Graduate School of Medical Sciences, Higashi-ku, Fukuoka (Japan); Takayama, Yukihisa [Kyushu University, Department of Radiology Informatics and Network, Graduate School of Medical Sciences, Higashi-ku, Fukuoka (Japan); Shirabe, Ken [Kyushu University, Department of Surgery and Science, Graduate School of Medical Sciences, Higashi-ku, Fukuoka (Japan); Aishima, Shinichi [Saga University Hospital, Department of Pathology and Microbiology, Faculty of Medicine, Saga City, Saga (Japan); Wang, Huanlin; Oda, Yoshinao [Kyushu University, Department of Anatomic Pathology, Graduate School of Medical Sciences, Higashi-ku, Fukuoka (Japan)

    2017-02-15

    To evaluate the relationship between the enhancement pattern of intrahepatic cholangiocarcinomas (ICCs) in the hepatic arterial phase (HAP) of dynamic hepatic CT and the clinicopathological findings with special reference to the perihilar type and the peripheral type. Forty-seven patients with pathologically proven ICCs were enrolled. Based on the enhancement pattern in the HAP, the lesions were classified into three groups: a hypovascular group (n=13), rim-enhancement group (n=18), and hypervascular group (n=16). The clinicopathological findings were compared among the three groups. Perihilar-type ICCs were significantly more frequently observed in the hypovascular group than in the rim-enhancement and hypervascular groups (p=0.006 and p <0.001, respectively). Lymphatic invasion, perineural invasion, and biliary invasion were significantly more frequent in the hypovascular group than the rim- enhancement group (p=0.001, p=0.025 and p=0.029, respectively) or hypervascular group (p <0.001, p <0.001 and p=0.025, respectively). Patients with hypovascular lesions showed significantly poorer disease-free survival than patients with rim-enhancing or hypervascular lesions (p=0.001 and p=0.001, respectively). Hypovascularity was an independent preoperative prognostic factor for disease-free survival (p<0.001). Hypovascular ICCs in the HAP tend to be of perihilar type and to have more malignant potential than other ICCs. (orig.)

  18. Polymer compositions, polymer films and methods and precursors for forming same

    Science.gov (United States)

    Klaehn, John R; Peterson, Eric S; Orme, Christopher J

    2013-09-24

    Stable, high performance polymer compositions including polybenzimidazole (PBI) and a melamine-formaldehyde polymer, such as methylated, poly(melamine-co-formaldehyde), for forming structures such as films, fibers and bulky structures. The polymer compositions may be formed by combining polybenzimidazole with the melamine-formaldehyde polymer to form a precursor. The polybenzimidazole may be reacted and/or intertwined with the melamine-formaldehyde polymer to form the polymer composition. For example, a stable, free-standing film having a thickness of, for example, between about 5 .mu.m and about 30 .mu.m may be formed from the polymer composition. Such films may be used as gas separation membranes and may be submerged into water for extended periods without crazing and cracking. The polymer composition may also be used as a coating on substrates, such as metal and ceramics, or may be used for spinning fibers. Precursors for forming such polymer compositions are also disclosed.

  19. Method for making a low density polyethylene waste form for safe disposal of low level radioactive material

    Science.gov (United States)

    Colombo, P.; Kalb, P.D.

    1984-06-05

    In the method of the invention low density polyethylene pellets are mixed in a predetermined ratio with radioactive particulate material, then the mixture is fed through a screw-type extruder that melts the low density polyethylene under a predetermined pressure and temperature to form a homogeneous matrix that is extruded and separated into solid monolithic waste forms. The solid waste forms are adapted to be safely handled, stored for a short time, and safely disposed of in approved depositories.

  20. Different radiolabelling methods alter the pharmacokinetic and biodistribution properties of Plasminogen Activator Inhibitor Type 2 (PAI-2) forms

    International Nuclear Information System (INIS)

    Ranson, Marie; Berghofer, Paula; Vine, Kara L.; Greguric, Ivan; Shepherd, Rachael; Katsifis, Andrew

    2012-01-01

    Introduction: Tumour-associated urokinase plasminogen activator (uPA) is a critical marker of invasion and metastasis, and it is recognised as having strong prognostic relevance as well as being a therapeutic target. The specific uPA inhibitor plasminogen activator inhibitor type-2 (PAI-2, SerpinB2) specifically targets cell bound uPA and is internalised. Furthermore, preclinical studies have established the “proof-of-principle” of uPA-targeting by PAI-2-cytotoxin conjugates in human carcinoma models. However, these studies also suggest that PAI-2 is rapidly cleared via the renal system with low total dose reaching the tumour. In this study, a comparative single photon emission computed tomography (SPECT) and biodistribution (BD) analysis of different forms of PAI-2 labelled with the radioisotopes iodine-123 ( 123 I) and technetium-99m ( 99m Tc) was undertaken. Methods: The pharmacokinetic (PK) properties and BD of wild-type, ΔCD-loop and PEGylated ΔCD-loop PAI-2 labelled with the commonly used diagnostic SPECT radioisotopes 99m Tc or 123 I were compared in mouse models of human prostate carcinoma. Whole body SPECT imaging was also performed. Results: Both wild-type and the shorter but active ΔCD-loop form of PAI-2 123 I-labelled indirectly via conjugation to free amine groups (termed 123 I-Bn-PAI-2) exhibited low tumour uptake, rapid excretion and similar PK profiles. Preliminary studies with a short branched-chain PEGylated 123 I-Bn-PAI-2 ΔCD-loop indicated an increase in blood retention time and tumour uptake. All 123 I-Bn-labelled radiotracers were largely excreted through the kidneys. By comparison, both wild-type 123 I-PAI-2 (labelled directly via tyrosine residues) and 99m Tc-PAI-2 displayed different PK/BD patterns compared to 123 I-Bn-PAI-2, suggesting greater liver based catabolism and thus slower elimination. SPECT imaging mimicked the BD results of all radiotracers. Conclusion: The different labelling methods gave distinct PAI-2 BD and tumour

  1. Locating previously unknown patterns in data-mining results: a dual data- and knowledge-mining method

    Directory of Open Access Journals (Sweden)

    Knaus William A

    2006-03-01

    Full Text Available Abstract Background Data mining can be utilized to automate analysis of substantial amounts of data produced in many organizations. However, data mining produces large numbers of rules and patterns, many of which are not useful. Existing methods for pruning uninteresting patterns have only begun to automate the knowledge acquisition step (which is required for subjective measures of interestingness, hence leaving a serious bottleneck. In this paper we propose a method for automatically acquiring knowledge to shorten the pattern list by locating the novel and interesting ones. Methods The dual-mining method is based on automatically comparing the strength of patterns mined from a database with the strength of equivalent patterns mined from a relevant knowledgebase. When these two estimates of pattern strength do not match, a high "surprise score" is assigned to the pattern, identifying the pattern as potentially interesting. The surprise score captures the degree of novelty or interestingness of the mined pattern. In addition, we show how to compute p values for each surprise score, thus filtering out noise and attaching statistical significance. Results We have implemented the dual-mining method using scripts written in Perl and R. We applied the method to a large patient database and a biomedical literature citation knowledgebase. The system estimated association scores for 50,000 patterns, composed of disease entities and lab results, by querying the database and the knowledgebase. It then computed the surprise scores by comparing the pairs of association scores. Finally, the system estimated statistical significance of the scores. Conclusion The dual-mining method eliminates more than 90% of patterns with strong associations, thus identifying them as uninteresting. We found that the pruning of patterns using the surprise score matched the biomedical evidence in the 100 cases that were examined by hand. The method automates the acquisition of

  2. Development and Validation of a UV Spectrophotometric and a RP-HPLC Methods for Moexipril Hydrochloride in Pure Form and Pharmaceutical Dosage Form

    International Nuclear Information System (INIS)

    Mastiholimath, V.S.; Gupte, P.P.; Mannur, V.S.

    2012-01-01

    A simple and reliable UV spectrophotometric and high-performance liquid chromatography (HPLC) methods were developed and validated for Moexipril hydrochloride in pure form and pharmaceutical dosage form. The RP-HPLC method was developed on agilant eclipse C 18 , (150 mm x 4.6 mm, 5 μm) with a mobile phase gradient system of 60 % (methanol:acetonitrile (70:30 % v/v)) : 40 % 20 mM ammonium acetate buffer pH 4.5 (v/v) and UV spectrophotometric method was developed in phosphate buffer pH 6.8. The effluent was monitored by SPD-M20A, prominence PDA detector at 210 nm. Calibration curve was linear over the concentration range of 10-35 μg/ml and 1-9 μg/ml for RP-HPLC and UV with a regression coefficient of 0.999. For RP-HPLC method Inter-day and intra-day precision % RSD values were found to be 1.00078 % and 1.49408 % respectively. For UV method 0.73386 % to 1.44111 % for inter day 0.453864 to 1.15542 intra-day precision. Recovery of Moexipril hydrochloride was found to be in the range of 99.8538 % to 101.5614 % and 100.5297586 % to 100.6431587 % for UV and RP-HPLC respectively. The limits of detection (LOD) and quantification (LOQ) for HPLC were 0.98969 and 2.99907 μg/ml, respectively. The developed RP-HPLC and UV spectrophotometric method was successfully applied for the quantitative determination of Moexipril hydrochloride in pharmaceutical dosage. (author)

  3. Differential abundances of four forms of Binder of SPerm 1 in the seminal plasma of Bos taurus indicus bulls with different patterns of semen freezability.

    Science.gov (United States)

    Magalhães, Marcos Jorge; Martins, Leonardo Franco; Senra, Renato Lima; Santos, Thaís Ferreira Dos; Okano, Denise Silva; Pereira, Paulo Roberto Gomes; Faria-Campos, Alessandra; Campos, Sérgio Vale Aguiar; Guimarães, José Domingos; Baracat-Pereira, Maria Cristina

    2016-08-01

    The Binder of SPerm 1 (BSP1) protein is involved in the fertilization and semen cryopreservation processes and is described to be both beneficial and detrimental to sperm. Previously, the relationship of BSP1 with freezability events has not been completely understood. The objective of this work was to determine the differential abundance of the forms of the BSP1 protein in cryopreserved seminal plasma of Bos taurus indicus bulls with different patterns of semen freezability using proteomics. A wide cohort of adult bulls with high genetic value from an artificial insemination center was used as donors of high quality, fresh semen. Nine bulls presenting different patterns of semen freezability were selected. Two-dimensional gel electrophoresis showed differential abundance in a group of seven protein spots in the frozen/thawed seminal plasma from the bulls, ranging from 15 to 17 kDa, with pI values from 4.6 to 5.8. Four of these spots were confirmed to be BSP1 using mass spectrometry, proteomics, biochemical, and computational analysis (Tukey's test at P semen freezability and its absence in bulls presenting high semen freezability. This is the first report showing that more than two forms of BSP1 are found in the seminal plasma of Nelore adult bulls and not all animals have a similar abundance of each BSP1 form. Different BSP1 forms may be involved in different events of fertilization and the cryopreservation process. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. Forms and methods of stimulation of innovative activities in the restructuring of production program

    Directory of Open Access Journals (Sweden)

    I. I. Emtcova

    2016-01-01

    Full Text Available In the Russian economy not every business entity, implements innovative business activities. The situation generated by the complexity of perception and practical transition to an innovative economic system. On the development of innovative activities affects the overall condition of the economy, condition of material production. The research demonstrates that resource potential of innovative activities in recent years had a tendency towards absolute quantitative reduction and quality deterioration. The decrease in the level and quality of resource provision of innovative activity due to the lack of necessary financial resources. Currently, innovation has become the primary means of increasing the profit of economic entities at the expense of better meet market demand, reduce production costs compared to competitors. Given the complexity of businesses, there is a need of the state stimulation of innovative activity, which is carried out the main directions, forms and methods. In the system of direct effects of the state on business innovation is the stimulation of development of Technopark structures. Creating the most favourable conditions for innovative enterprises, the provision of various services is their main goal. For the food processing industry currently, the largest share in the investments in the investment activities have their own sources of funding, including the use of depreciation. To Finance industry-wide, cross-sectoral and regional scientific and technical problems you can create extra-budgetary funds for financing R & d and innovation support. To encourage regional interests, one of which is that innovation is available to local authorities. In the financial provision of innovative activity is given credit. A Bank loan allows you to increase the efficiency of innovation activity. The article concludes that these measures to stimulate innovative-innovative activity can effectively influence the activity of the company: will

  5. Chemical bridges for enhancing hydrogen storage by spillover and methods for forming the same

    Science.gov (United States)

    Yang, Ralph T.; Li, Yingwei; Qi, Gongshin; Lachawiec, Jr., Anthony J.

    2012-12-25

    A composition for hydrogen storage includes a source of hydrogen atoms, a receptor, and a chemical bridge formed between the source and the receptor. The chemical bridge is formed from a precursor material. The receptor is adapted to receive hydrogen spillover from the source.

  6. Optimal assignment methods in three-form planned missing data designs for longitudinal panel studies

    NARCIS (Netherlands)

    Jorgensen, T.D.; Rhemtulla, M.; Schoemann, A.; McPherson, B.; Wu, W.; Little, T.D.

    2014-01-01

    Planned missing designs are becoming increasingly popular, but because there is no consensus on how to implement them in longitudinal research, we simulated longitudinal data to distinguish between strategies of assigning items to forms and of assigning forms to participants across measurement

  7. Application of Power Geometry and Normal Form Methods to the Study of Nonlinear ODEs

    Science.gov (United States)

    Edneral, Victor

    2018-02-01

    This paper describes power transformations of degenerate autonomous polynomial systems of ordinary differential equations which reduce such systems to a non-degenerative form. Example of creating exact first integrals of motion of some planar degenerate system in a closed form is given.

  8. Application of Power Geometry and Normal Form Methods to the Study of Nonlinear ODEs

    Directory of Open Access Journals (Sweden)

    Edneral Victor

    2018-01-01

    Full Text Available This paper describes power transformations of degenerate autonomous polynomial systems of ordinary differential equations which reduce such systems to a non-degenerative form. Example of creating exact first integrals of motion of some planar degenerate system in a closed form is given.

  9. Visibility Network Patterns and Methods for Studying Visual Relational Phenomena in Archeology

    Directory of Open Access Journals (Sweden)

    Tom Brughmans

    2017-08-01

    Full Text Available A review of the archeological and non-archeological use of visibility networks reveals the use of a limited range of formal techniques, in particular for representing visibility theories. This paper aims to contribute to the study of complex visual relational phenomena in landscape archeology by proposing a range of visibility network patterns and methods. We propose first- and second-order visibility graph representations of total and cumulative viewsheds, and two-mode representations of cumulative viewsheds. We present network patterns that can be used to represent aspects of visibility theories and that can be used in statistical simulation models to compare theorized networks with observed networks. We argue for the need to incorporate observed visibility network density in these simulation models, by illustrating strong differences in visibility network density in three example landscapes. The approach is illustrated through a brief case study of visibility networks of long barrows in Cranborne Chase.

  10. Novel fabrication of flexible graphene-based chemical sensors with heaters using soft lithographic patterning method.

    Science.gov (United States)

    Jung, Min Wook; Myung, Sung; Song, Wooseok; Kang, Min-A; Kim, Sung Ho; Yang, Cheol-Soo; Lee, Sun Sook; Lim, Jongsun; Park, Chong-Yun; Lee, Jeong-O; An, Ki-Seok

    2014-08-27

    We have fabricated graphene-based chemical sensors with flexible heaters for the highly sensitive detection of specific gases. We believe that increasing the temperature of the graphene surface significantly enhanced the electrical signal change of the graphene-based channel, and reduced the recovery time needed to obtain a normal state of equilibrium. In addition, a simple and efficient soft lithographic patterning process was developed via surface energy modification for advanced, graphene-based flexible devices, such as gas sensors. As a proof of concept, we demonstrated the high sensitivity of NO2 gas sensors based on graphene nanosheets. These devices were fabricated using a simple soft-lithographic patterning method, where flexible graphene heaters adjacent to the channel of sensing graphene were utilized to control graphene temperature.

  11. Design of environmental monitoring system of nuclear facility based on a method of pattern recognition

    Energy Technology Data Exchange (ETDEWEB)

    Katoh, N; Kiyose, R; Yamamoto, Y [Tokyo Univ. (Japan). Faculty of Engineering

    1977-10-01

    The problem to optimize the number and locations of environmental radiation monitoring detectors is formulated by taking the specifically defined distance measures as a performance index and solved numerically using heuristic programming such as branch and bound method. An ideal numerical example neglecting noises due to background radiation, shows that the desirable number and locations of detectors are determined mainly by the atmospheric conditions and are not significantly influenced by the variation of the rate and pattern of activity release from the nuclear facility. It is shown also that the appropriate and sufficient number of monitoring detectors to be located around the facility will be from three to six at most, if considered from the viewpoint of pattern recognition.

  12. Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles

    Directory of Open Access Journals (Sweden)

    Lee Yun-Shien

    2008-03-01

    Full Text Available Abstract Background The hierarchical clustering tree (HCT with a dendrogram 1 and the singular value decomposition (SVD with a dimension-reduced representative map 2 are popular methods for two-way sorting the gene-by-array matrix map employed in gene expression profiling. While HCT dendrograms tend to optimize local coherent clustering patterns, SVD leading eigenvectors usually identify better global grouping and transitional structures. Results This study proposes a flipping mechanism for a conventional agglomerative HCT using a rank-two ellipse (R2E, an improved SVD algorithm for sorting purpose seriation by Chen 3 as an external reference. While HCTs always produce permutations with good local behaviour, the rank-two ellipse seriation gives the best global grouping patterns and smooth transitional trends. The resulting algorithm automatically integrates the desirable properties of each method so that users have access to a clustering and visualization environment for gene expression profiles that preserves coherent local clusters and identifies global grouping trends. Conclusion We demonstrate, through four examples, that the proposed method not only possesses better numerical and statistical properties, it also provides more meaningful biomedical insights than other sorting algorithms. We suggest that sorted proximity matrices for genes and arrays, in addition to the gene-by-array expression matrix, can greatly aid in the search for comprehensive understanding of gene expression structures. Software for the proposed methods can be obtained at http://gap.stat.sinica.edu.tw/Software/GAP.

  13. A simple field method to identify foot strike pattern during running.

    Science.gov (United States)

    Giandolini, Marlène; Poupard, Thibaut; Gimenez, Philippe; Horvais, Nicolas; Millet, Guillaume Y; Morin, Jean-Benoît; Samozino, Pierre

    2014-05-07

    Identifying foot strike patterns in running is an important issue for sport clinicians, coaches and footwear industrials. Current methods allow the monitoring of either many steps in laboratory conditions or only a few steps in the field. Because measuring running biomechanics during actual practice is critical, our purpose is to validate a method aiming at identifying foot strike patterns during continuous field measurements. Based on heel and metatarsal accelerations, this method requires two uniaxial accelerometers. The time between heel and metatarsal acceleration peaks (THM) was compared to the foot strike angle in the sagittal plane (αfoot) obtained by 2D video analysis for various conditions of speed, slope, footwear, foot strike and state of fatigue. Acceleration and kinematic measurements were performed at 1000Hz and 120Hz, respectively, during 2-min treadmill running bouts. Significant correlations were observed between THM and αfoot for 14 out of 15 conditions. The overall correlation coefficient was r=0.916 (Pstrike except for extreme forefoot strike during which the heel rarely or never strikes the ground, and for different footwears and states of fatigue. We proposed a classification based on THM: FFS<-5.49msmethod, it is reliable for distinguishing rearfoot and non-rearfoot strikers in situ. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. The Analysis Performance Method Naive Bayes Andssvm Determine Pattern Groups of Disease

    Science.gov (United States)

    Sitanggang, Rianto; Tulus; Situmorang, Zakarias

    2017-12-01

    Information is a very important element and into the daily needs of the moment, to get a precise and accurate information is not easy, this research can help decision makers and make a comparison. Researchers perform data mining techniques to analyze the performance of methods and algorithms naïve Bayes methods Smooth Support Vector Machine (ssvm) in the grouping of the disease.The pattern of disease that is often suffered by people in the group can be in the detection area of the collection of information contained in the medical record. Medical records have infromasi disease by patients in coded according to standard WHO. Processing of medical record data to find patterns of this group of diseases that often occur in this community take the attribute address, sex, type of disease, and age. Determining the next analysis is grouping of four ersebut attribute. From the results of research conducted on the dataset fever diabete mellitus, naïve Bayes method produces an average value of 99% and an accuracy and SSVM method produces an average value of 93% accuracy

  15. Validated sensitive spectrofluorimetric method for determination of antihistaminic drug azelastine HCl in pure form and in pharmaceutical dosage forms: application to stability study.

    Science.gov (United States)

    El-Masry, Amal A; Hammouda, Mohammed E A; El-Wasseef, Dalia R; El-Ashry, Saadia M

    2017-03-01

    A highly sensitive, simple and rapid spectrofluorimetric method was developed for the determination of azelastine HCl (AZL) in either its pure state or pharmaceutical dosage form. The proposed method was based on measuring the native fluorescence of the studied drug in 0.2 M H 2 SO 4 at λ em  = 364 nm after excitation at λ ex  = 275 nm. Different experimental parameters were studied and optimized carefully to obtain the highest fluorescence intensity. The proposed method showed a linear dependence of the fluorescence intensity on drug concentration over a concentration range of 10-250 ng/mL, with a limit of detection of 1.52 ng/mL and limit of quantitation of 4.61 ng/mL. Moreover, the method was successfully applied to pharmaceutical preparations, with percent recovery values (± SD) of 99.96 (± 0.4) and 100.1 (± 0.52) for nasal spray and eye drops, respectively. The results were in good agreement with those obtained by the comparison method, as revealed by Student's t-test and the variance ratio F-test. The method was extended to study the stability of AZL under stress conditions, where the drug was exposed to neutral, acidic, alkaline, oxidative and photolytic degradation according to International Conference on Harmonization (ICH) guidelines. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  16. Validation of the stream function method used for reconstruction of experimental ionospheric convection patterns

    Directory of Open Access Journals (Sweden)

    P.L. Israelevich

    Full Text Available In this study we test a stream function method suggested by Israelevich and Ershkovich for instantaneous reconstruction of global, high-latitude ionospheric convection patterns from a limited set of experimental observations, namely, from the electric field or ion drift velocity vector measurements taken along two polar satellite orbits only. These two satellite passes subdivide the polar cap into several adjacent areas. Measured electric fields or ion drifts can be considered as boundary conditions (together with the zero electric potential condition at the low-latitude boundary for those areas, and the entire ionospheric convection pattern can be reconstructed as a solution of the boundary value problem for the stream function without any preliminary information on ionospheric conductivities. In order to validate the stream function method, we utilized the IZMIRAN electrodynamic model (IZMEM recently calibrated by the DMSP ionospheric electrostatic potential observations. For the sake of simplicity, we took the modeled electric fields along the noon-midnight and dawn-dusk meridians as the boundary conditions. Then, the solution(s of the boundary value problem (i.e., a reconstructed potential distribution over the entire polar region is compared with the original IZMEM/DMSP electric potential distribution(s, as well as with the various cross cuts of the polar cap. It is found that reconstructed convection patterns are in good agreement with the original modelled patterns in both the northern and southern polar caps. The analysis is carried out for the winter and summer conditions, as well as for a number of configurations of the interplanetary magnetic field.

    Key words: Ionosphere (electric fields and currents; plasma convection; modelling and forecasting

  17. An experimental comparison of three wire beam electrode based methods for determining corrosion rates and patterns

    International Nuclear Information System (INIS)

    Tan, Y.-J.

    2005-01-01

    Laboratory experiments have been carried out to examine the advantages and limitations of three wire beam electrode (WBE) based techniques, including the noise resistance R n -WBE method, the overpotential-galvanic current method, and the galvanic current method, in determining corrosion rates and patterns. These techniques have been applied simultaneously to several selected corrosion systems of different characteristics. It has been found that the R n -WBE method has advantages over other WBE based methods when applying to WBE surfaces under uniform corrosion. However, the R n -WBE method has been found to be unsuitable for low noise level corrosion systems. It has also been found that both R n -WBE and overpotential-galvanic current methods are similarly applicable to WBE surfaces under nonuniform corrosion. However, the galvanic current method has been found to be suitable only for WBE surfaces under highly localised corrosion. Some related issues regarding R n calculation such as trend removal and its effects on corrosion mapping have also been discussed

  18. Utilization pattern of extension tools and methods by Agricultural Extension Agents

    Directory of Open Access Journals (Sweden)

    M Surudhi

    2018-05-01

    Full Text Available A study was conducted in Krishnagiri district of Tamil Nadu state to understand the utilization pattern of extension tools and methods by the agricultural extension agents. As ICT revolution is slowly conquering the rural sector, it becomes imperative that the agricultural extension agents transform themselves to the changing times and develop competencies in utilizing these ICTs.  The study explored the usage of various extension tools and methods by the change agents and the constraints faced in utilizing them. The findings revealed that the extension functionaries frequently used the individual contact methods viz., telephone, office calls and farm and home visits in the process of transfer of technology. Least efforts were shown in sending SMS based communication. Meetings were the common and frequently adopted group contact method. Demonstrations, farmer field school, farmer’s interest groups, field trips and farmer training programmes were moderately adopted. Posters, leaflets and pre-season campaigns were the widely adopted mass contact methods. They possess least skill in utilizing farm magazines, presenting television and radio programmes, which are among the most popular and most efficient mass contact methods. The extension functionaries need to be trained adequately on the wider use of electronic communication methods like e mails, and SMS in the local language. Efforts should be taken up to sensitize the importance and train the extension agents in the usage of different group and mass contact methods.

  19. An novel frequent probability pattern mining algorithm based on circuit simulation method in uncertain biological networks

    Science.gov (United States)

    2014-01-01

    Background Motif mining has always been a hot research topic in bioinformatics. Most of current research on biological networks focuses on exact motif mining. However, due to the inevitable experimental error and noisy data, biological network data represented as the probability model could better reflect the authenticity and biological significance, therefore, it is more biological meaningful to discover probability motif in uncertain biological networks. One of the key steps in probability motif mining is frequent pattern discovery which is usually based on the possible world model having a relatively high computational complexity. Methods In this paper, we present a novel method for detecting frequent probability patterns based on circuit simulation in the uncertain biological networks. First, the partition based efficient search is applied to the non-tree like subgraph mining where the probability of occurrence in random networks is small. Then, an algorithm of probability isomorphic based on circuit simulation is proposed. The probability isomorphic combines the analysis of circuit topology structure with related physical properties of voltage in order to evaluate the probability isomorphism between probability subgraphs. The circuit simulation based probability isomorphic can avoid using traditional possible world model. Finally, based on the algorithm of probability subgraph isomorphism, two-step hierarchical clustering method is used to cluster subgraphs, and discover frequent probability patterns from the clusters. Results The experiment results on data sets of the Protein-Protein Interaction (PPI) networks and the transcriptional regulatory networks of E. coli and S. cerevisiae show that the proposed method can efficiently discover the frequent probability subgraphs. The discovered subgraphs in our study contain all probability motifs reported in the experiments published in other related papers. Conclusions The algorithm of probability graph isomorphism

  20. Turbine component having surface cooling channels and method of forming same

    Science.gov (United States)

    Miranda, Carlos Miguel; Trimmer, Andrew Lee; Kottilingam, Srikanth Chandrudu

    2017-09-05

    A component for a turbine engine includes a substrate that includes a first surface, and an insert coupled to the substrate proximate the substrate first surface. The component also includes a channel. The channel is defined by a first channel wall formed in the substrate and a second channel wall formed by at least one coating disposed on the substrate first surface. The component further includes an inlet opening defined in flow communication with the channel. The inlet opening is defined by a first inlet wall formed in the substrate and a second inlet wall defined by the insert.

  1. Microneedle fabrication using the plane pattern to cross-section transfer method

    Science.gov (United States)

    Khumpuang, Sommawan; Horade, Mitsuhiro; Fujioka, Kazuya; Sugiyama, Susumu

    2006-04-01

    In this paper, microneedle fabrication using the PCT (plane pattern to cross-section transfer) method is summarized. Three types of microneedle array have been developed: the single-tip, quadruplet, and hollow microneedle arrays. A brief introduction to the fabrication process using PCT and detailed design concepts for optimizing the fabrication steps for shape improvement of the three types of microneedle are provided. The microneedle structures have controllable angled sidewalls, exhibiting an extraordinarily geometrical level of accuracy compared to what is achieved using other existing fabrication methods based on deep x-ray lithography by synchrotron radiation. Furthermore, the improvements reported in this work as compared to the results from the existing methods are: sharper tips for the single-tip microneedles, strength improvement for the quadruplet microneedles, and cost reduction for the hollow microneedles. Each type of microneedle was designed to serve a different biomedical need.

  2. Forming a method mindset : The role of knowledge and preference in facilitating heuristic method usage in design

    NARCIS (Netherlands)

    Daalhuizen, J.J.; Person, F.E.O.K.; Gattol, V.

    2013-01-01

    Both systematic and heuristic methods are common practice when designing. Yet, in teaching students how to design, heuristic methods are typically only granted a secondary role. So, how do designers and students develop a mindset for using heuristic methods? In this paper, we study how prior

  3. Method for fabricating five-level microelectromechanical structures and microelectromechanical transmission formed

    Science.gov (United States)

    Rodgers, M. Steven; Sniegowski, Jeffry J.; Miller, Samuel L.; McWhorter, Paul J.

    2000-01-01

    A process for forming complex microelectromechanical (MEM) devices having five layers or levels of polysilicon, including four structural polysilicon layers wherein mechanical elements can be formed, and an underlying polysilicon layer forming a voltage reference plane. A particular type of MEM device that can be formed with the five-level polysilicon process is a MEM transmission for controlling or interlocking mechanical power transfer between an electrostatic motor and a self-assembling structure (e.g. a hinged pop-up mirror for use with an incident laser beam). The MEM transmission is based on an incomplete gear train and a bridging set of gears that can be moved into place to complete the gear train to enable power transfer. The MEM transmission has particular applications as a safety component for surety, and for this purpose can incorporate a pin-in-maze discriminator responsive to a coded input signal.

  4. Method for fabricating five-level microelectromechanical structures and microelectromechanical transmission formed

    Energy Technology Data Exchange (ETDEWEB)

    Rodgers, M.S.; Sniegowski, J.J.; Miller, S.L.; McWhorter, P.J.

    2000-07-04

    A process is disclosed for forming complex microelectromechanical (MEM) devices having five layers or levels of polysilicon, including four structural polysilicon layers wherein mechanical elements can be formed, and an underlying polysilicon layer forming a voltage reference plane. A particular type of MEM device that can be formed with the five-level polysilicon process is a MEM transmission for controlling or interlocking mechanical power transfer between an electrostatic motor and a self-assembling structure (e.g. a hinged pop-up mirror for use with an incident laser beam). The MEM transmission is based on an incomplete gear train and a bridging set of gears that can be moved into place to complete the gear train to enable power transfer. The MEM transmission has particular applications as a safety component for surety, and for this purpose can incorporate a pin-in-maze discriminator responsive to a coded input signal.

  5. A task specific uncertainty analysis method for least-squares-based form characterization of ultra-precision freeform surfaces

    International Nuclear Information System (INIS)

    Ren, M J; Cheung, C F; Kong, L B

    2012-01-01

    In the measurement of ultra-precision freeform surfaces, least-squares-based form characterization methods are widely used to evaluate the form error of the measured surfaces. Although many methodologies have been proposed in recent years to improve the efficiency of the characterization process, relatively little research has been conducted on the analysis of associated uncertainty in the characterization results which may result from those characterization methods being used. As a result, this paper presents a task specific uncertainty analysis method with application in the least-squares-based form characterization of ultra-precision freeform surfaces. That is, the associated uncertainty in the form characterization results is estimated when the measured data are extracted from a specific surface with specific sampling strategy. Three factors are considered in this study which include measurement error, surface form error and sample size. The task specific uncertainty analysis method has been evaluated through a series of experiments. The results show that the task specific uncertainty analysis method can effectively estimate the uncertainty of the form characterization results for a specific freeform surface measurement

  6. The Linear Quadratic Gaussian Multistage Game with Nonclassical Information Pattern Using a Direct Solution Method

    Science.gov (United States)

    Clemens, Joshua William

    Game theory has application across multiple fields, spanning from economic strategy to optimal control of an aircraft and missile on an intercept trajectory. The idea of game theory is fascinating in that we can actually mathematically model real-world scenarios and determine optimal decision making. It may not always be easy to mathematically model certain real-world scenarios, nonetheless, game theory gives us an appreciation for the complexity involved in decision making. This complexity is especially apparent when the players involved have access to different information upon which to base their decision making (a nonclassical information pattern). Here we will focus on the class of adversarial two-player games (sometimes referred to as pursuit-evasion games) with nonclassical information pattern. We present a two-sided (simultaneous) optimization solution method for the two-player linear quadratic Gaussian (LQG) multistage game. This direct solution method allows for further interpretation of each player's decision making (strategy) as compared to previously used formal solution methods. In addition to the optimal control strategies, we present a saddle point proof and we derive an expression for the optimal performance index value. We provide some numerical results in order to further interpret the optimal control strategies and to highlight real-world application of this game-theoretic optimal solution.

  7. Brain activation patterns resulting from learning letter forms through active self-production and passive observation in young children

    Directory of Open Access Journals (Sweden)

    Alyssa J Kersey

    2013-09-01

    Full Text Available Although previous literature suggests that writing practice facilitates neural specialization for letters, it is unclear if this facilitation is driven by the perceptual feedback from the act of writing or the actual execution of the motor act. The present study addresses this issue by measuring the change in BOLD signal in response to hand-printed letters, unlearned cursive letters, and cursive letters that 7 year-old children learned actively, by writing, and passively, by observing an experimenter write. Brain activation was assessed using fMRI while perceiving letters – in both cursive and manuscript forms. Results showed that active training led to increased recruitment of the sensori-motor network associated with letter perception as well as the insula and claustrum, but passive observation did not. This suggests that perceptual networks for newly learned cursive letters are driven by motor execution rather than by perceptual feedback.

  8. Application of Pattern Recognition Method for Color Assessment of Oriental Tobacco based on HPLC of Polyphenols

    Directory of Open Access Journals (Sweden)

    Dagnon S

    2014-12-01

    Full Text Available The color of Oriental tobaccos was organoleptically assayed, and high performance liquid chromatography (HPLC of polyphenols was performed. The major tobacco polyphenols (chlorogenic acid, its isomers, and rutin, as well as scopoletin and kaempferol-3-rutinoside were quantified. HPLC polyphenol profiles were processed by pattern recognition method (PRM, and the values of indexes of similarity (Is,% between the cultivars studied were determined. It was shown that data from organoleptic color assessment and from PRM based on HPLC profiles of polyphenols of the cultivars studied are largely compatible. Hence, PRM can be suggested as an additional tool for objective color evaluation and classification of Oriental tobacco.

  9. A plateau–valley separation method for textured surfaces with a deterministic pattern

    DEFF Research Database (Denmark)

    Godi, Alessandro; Kühle, Anders; De Chiffre, Leonardo

    2014-01-01

    The effective characterization of textured surfaces presenting a deterministic pattern of lubricant reservoirs is an issue with which many researchers are nowadays struggling. Existing standards are not suitable for the characterization of such surfaces, providing at times values without physical...... meaning. A new method based on the separation between the plateau and valley regions is hereby presented allowing independent functional analyses of the detected features. The determination of a proper threshold between plateaus and valleys is the first step of a procedure resulting in an efficient...

  10. The method to make the three dimensional anatomical pattern of hepatic vessels by stereo angiography

    International Nuclear Information System (INIS)

    Mutou, Haruomi; Kobayashi, Seiichiro; Yamada, Akiyoshi; Takasaki, Takeshi; Isobe, Yoshinori; Tanaka, Seiichi; Saeki, Shin; Yoshida, Masanori

    1986-01-01

    For the Past few years, there has been a big advance in the hepatic surgery. Now, small resection, such as segmentectomy or subsegmentectomy, is performed routinely. Based on this tendency, hepatic surgeons request more details, more stereographic findings of hepatic vessels to heaptic angiography. Especially three dimensional combined anatomical pattern of the hepatic artery, portal vein and hepatic vein is strongly needed. We have tried three dimensional computer graphic of hepatic vessels since few years ago, using the personal computer, digitizer with clear screen, commercially available 3D software and my own program. We use three groups of angiographic films, that is the hepatic artery, portal vein and hepatic vein with IVC, which were taken by stereoangiography. The depth of each poits of vessels are calculated by the way described in Fig 3. Using these points, the 3D software, '3DPROGATS', can make the anatomical pattern of combined hepatic vessels on TV display. And then we can also perform rotation, heading, bank, zooming, hidden line elimination freely for this picture. Out of necessity as hepatic surgeons, we make a simple system for 3D computer graphic of heptic vessels. At present, the image is somewhat rough, but clinically it is relatively effective. In this report we want to explain our method and to show the anatomical pattern of hepatic vessels of case of hepatoma. (author)

  11. Bombyx mori and Aedes aegypti form multi-functional immune complexes that integrate pattern recognition, melanization, coagulants, and hemocyte recruitment.

    Science.gov (United States)

    Phillips, Dennis R; Clark, Kevin D

    2017-01-01

    The innate immune system of insects responds to wounding and pathogens by mobilizing multiple pathways that provide both systemic and localized protection. Key localized responses in hemolymph include melanization, coagulation, and hemocyte encapsulation, which synergistically seal wounds and envelop and destroy pathogens. To be effective, these pathways require a targeted deposition of their components to provide protection without compromising the host. Extensive research has identified a large number of the effectors that comprise these responses, but questions remain regarding their post-translational processing, function, and targeting. Here, we used mass spectrometry to demonstrate the integration of pathogen recognition proteins, coagulants, and melanization components into stable, high-mass, multi-functional Immune Complexes (ICs) in Bombyx mori and Aedes aegypti. Essential proteins common to both include phenoloxidases, apolipophorins, serine protease homologs, and a serine protease that promotes hemocyte recruitment through cytokine activation. Pattern recognition proteins included C-type Lectins in B. mori, while A. aegypti contained a protein homologous to Plasmodium-resistant LRIM1 from Anopheles gambiae. We also found that the B. mori IC is stabilized by extensive transglutaminase-catalyzed cross-linking of multiple components. The melanization inhibitor Egf1.0, from the parasitoid wasp Microplitis demolitor, blocked inclusion of specific components into the IC and also inhibited transglutaminase activity. Our results show how coagulants, melanization components, and hemocytes can be recruited to a wound surface or pathogen, provide insight into the mechanism by which a parasitoid evades this immune response, and suggest that insects as diverse as Lepidoptera and Diptera utilize similar defensive mechanisms.

  12. DNA sequencing, anatomy, and calcification patterns support a monophyletic, subarctic, carbonate reef-forming Clathromorphum (Hapalidiaceae, Corallinales, Rhodophyta).

    Science.gov (United States)

    Adey, Walter H; Hernandez-Kantun, Jazmin J; Johnson, Gabriel; Gabrielson, Paul W

    2015-02-01

    For the first time, morpho-anatomical characters that were congruent with DNA sequence data were used to characterize several genera in Hapalidiaceae-the major eco-engineers of Subarctic carbonate ecosystems. DNA sequencing of three genes (SSU, rbcL, ribulose-1, 5-bisphosphate carboxylase/oxygenase large subunit gene and psbA, photosystem II D1 protein gene), along with patterns of cell division, cell elongation, and calcification supported a monophyletic Clathromorphum. Two characters were diagnostic for this genus: (i) cell division, elongation, and primary calcification occurred only in intercalary meristematic cells and in a narrow vertical band (1-2 μm wide) resulting in a "meristem split" and (ii) a secondary calcification of interfilament crystals was also produced. Neopolyporolithon was resurrected for N. reclinatum, the generitype, and Clathromorphum loculosum was transferred to this genus. Like Clathromorphum, cell division, elongation, and calcification occurred only in intercalary meristematic cells, but in a wider vertical band (over 10-20 μm), and a "meristem split" was absent. Callilithophytum gen. nov. was proposed to accommodate Clathromorphum parcum, the obligate epiphyte of the northeast Pacific endemic geniculate coralline, Calliarthron. Diagnostic for this genus were epithallial cells terminating all cell filaments (no dorsi-ventrality was present), and a distinct "foot" was embedded in the host. Leptophytum, based on its generitype, L. laeve, was shown to be a distinct genus more closely related to Clathromorphum than to Phymatolithon. All names of treated species were applied unequivocally by linking partial rbcL sequences from holotype, isotype, or epitype specimens with field-collected material. Variation in rbcL and psbA sequences suggested that multiple species may be passing under each currently recognized species of Clathromorphum and Neopolyporolithon. © 2014 Phycological Society of America.

  13. Understanding flood-induced water chemistry variability extracting temporal patterns with the LDA method

    Science.gov (United States)

    Aubert, A. H.; Tavenard, R.; Emonet, R.; De Lavenne, A.; Malinowski, S.; Guyet, T.; Quiniou, R.; Odobez, J.; Merot, P.; Gascuel-odoux, C.

    2013-12-01

    events. The patterns themselves are carefully studied, as well as their repartition along the year and along the 12 years of the dataset. We would recommend the use of such model to any study based on patterns or signature extraction. It could be well suited to compare different geographical locations and analyzing the resulting different pattern distributions. (1) Aubert, A.H., Gascuel-Odoux, C., Gruau, G., Akkal, N., Faucheux, M., Fauvel, Y., Grimaldi, C., Hamon, Y., Jaffrezic, A., Lecoz Boutnik, M., Molenat, J., Petitjean, P., Ruiz, L., Merot, Ph. (2013), Solute transport dynamics in small, shallow groundwater-dominated agricultural catchments: insights from a high-frequency, multisolute 10 yr-long monitoring study. Hydrol. Earth Syst. Sci., 17(4): 1379-1391. (2) Aubert, A.H., Tavenard, R, Emonet, R., de Lavenne, A., Malinowski, S., Guyet, T., Quiniou, R., Odobez, J.-M., Merot, Ph., Gascuel-Odoux, C., submitted to WRR. Clustering with a probabilistic method newly applied in hydrology: application on flood events from water quality time-series.

  14. Solitary wave solutions to the modified form of Camassa-Holm equation by means of the homotopy analysis method

    International Nuclear Information System (INIS)

    Abbasbandy, S.

    2009-01-01

    Solitary wave solutions to the modified form of Camassa-Holm (CH) equation are sought. In this work, the homotopy analysis method (HAM), one of the most effective method, is applied to obtain the soliton wave solutions with and without continuity of first derivatives at crest

  15. Influence of urban form on landscape pattern and connectivity in metropolitan regions: a comparative case study of Phoenix, AZ, USA, and Izmir, Turkey.

    Science.gov (United States)

    Park, Sohyun; Hepcan, Çiğdem C; Hepcan, Şerif; Cook, Edward A

    2014-10-01

    Although ecological connectivity conservation in urban areas has recently been recognized as an important issue, less is known about its relationship to urban form and landscape pattern. This study investigates how urban morphology influences regional ecosystem pattern and landscape connectivity. Two metropolitan landscapes, Phoenix, AZ, USA, and Izmir, Turkey, were compared, both of which are fast-growing regions in their national context. A wide range of variables were considered for identifying natural and urban properties. The natural characteristics include typology of urban ecosystems, urban to natural cover ratio, dominant habitat type, urban biodiversity, landscape context, and connectivity conservation efforts. Urban parameters examine urban form, urban extent, urban cover proportion, growth rate, populations, urban gradient, major drivers of urbanization, urban density, and mode/approach of urban development. Twelve landscape metrics were measured and compared across the natural patches. Results show that there is little difference in landscape connectivity in the rural zones of Phoenix and Izmir, although Phoenix has slightly higher connectivity values. The connectivity variance in urbanized areas, however, is significantly dependent on the region. For example, Phoenix urban zones have substantially lower connectivity than either urban or suburban zones in Izmir. Findings demonstrate that small and compact urban settlements with more dense populations are more likely to conserve landscape connectivity compared to multiple-concentric but amalgamated urban form spreading all over the landscape (aka urban sprawl).

  16. New Spectrophotometric and Conductometric Methods for Macrolide Antibiotics Determination in Pure and Pharmaceutical Dosage Forms Using Rose Bengal

    Directory of Open Access Journals (Sweden)

    Rania A. Sayed

    2013-01-01

    Full Text Available Two Simple, accurate, precise, and rapid spectrophotometric and conductometric methods were developed for the estimation of erythromycin thiocyanate (I, clarithromycin (II, and azithromycin dihydrate (III in both pure and pharmaceutical dosage forms. The spectrophotometric procedure depends on the reaction of rose bengal and copper with the cited drugs to form stable ternary complexes which are extractable with methylene chloride, and the absorbances were measured at 558, 557, and 560 nm for (I, (II, and (III, respectively. The conductometric method depends on the formation of an ion-pair complex between the studied drug and rose bengal. For the spectrophotometric method, Beer's law was obeyed. The correlation coefficient ( for the studied drugs was found to be 0.9999. The molar absorptivity (, Sandell’s sensitivity, limit of detection (LOD, and limit of quantification (LOQ were also calculated. The proposed methods were successfully applied for the determination of certain pharmaceutical dosage forms containing the studied drugs

  17. Parity among interpretation methods of MLEE patterns and disparity among clustering methods in epidemiological typing of Candida albicans.

    Science.gov (United States)

    Boriollo, Marcelo Fabiano Gomes; Rosa, Edvaldo Antonio Ribeiro; Gonçalves, Reginaldo Bruno; Höfling, José Francisco

    2006-03-01

    The typing of C. albicans by MLEE (multilocus enzyme electrophoresis) is dependent on the interpretation of enzyme electrophoretic patterns, and the study of the epidemiological relationships of these yeasts can be conducted by cluster analysis. Therefore, the aims of the present study were to first determine the discriminatory power of genetic interpretation (deduction of the allelic composition of diploid organisms) and numerical interpretation (mere determination of the presence and absence of bands) of MLEE patterns, and then to determine the concordance (Pearson product-moment correlation coefficient) and similarity (Jaccard similarity coefficient) of the groups of strains generated by three cluster analysis models, and the discriminatory power of such models as well [model A: genetic interpretation, genetic distance matrix of Nei (d(ij)) and UPGMA dendrogram; model B: genetic interpretation, Dice similarity matrix (S(D1)) and UPGMA dendrogram; model C: numerical interpretation, Dice similarity matrix (S(D2)) and UPGMA dendrogram]. MLEE was found to be a powerful and reliable tool for the typing of C. albicans due to its high discriminatory power (>0.9). Discriminatory power indicated that numerical interpretation is a method capable of discriminating a greater number of strains (47 versus 43 subtypes), but also pointed to model B as a method capable of providing a greater number of groups, suggesting its use for the typing of C. albicans by MLEE and cluster analysis. Very good agreement was only observed between the elements of the matrices S(D1) and S(D2), but a large majority of the groups generated in the three UPGMA dendrograms showed similarity S(J) between 4.8% and 75%, suggesting disparities in the conclusions obtained by the cluster assays.

  18. Light extinction method for diagnostics of particles sizes formed in magnetic field

    Science.gov (United States)

    Myshkin, Vyacheslav; Izhoykin, Dmitry; Grigoriev, Alexander; Gamov, Denis; Leonteva, Daria

    2018-03-01

    The results of laser diagnostics of dispersed particles formed upon cooling of Zn vapor are presented. The radiation attenuation in the wavelength range 420-630 nm with a step of 0.3 nm was registered. The attenuation coefficients spectral dependence was processed using known algorithms for integral equation solving. The 10 groups of 8 attenuation coefficients were formed. Each group was processed taking with considering of previous decisions. After processing of the 10th group of data, calculations were repeated from the first one. Data of the particles sizes formed in a magnetic field of 0, 44 and 76 mT are given. A model of physical processes in a magnetic field is discussed.

  19. Diffuse nitrogen loss simulation and impact assessment of stereoscopic agriculture pattern by integrated water system model and consideration of multiple existence forms

    Science.gov (United States)

    Zhang, Yongyong; Gao, Yang; Yu, Qiang

    2017-09-01

    Agricultural nitrogen loss becomes an increasingly important source of water quality deterioration and eutrophication, even threatens water safety for humanity. Nitrogen dynamic mechanism is still too complicated to be well captured at watershed scale due to its multiple existence forms and instability, disturbance of agricultural management practices. Stereoscopic agriculture is a novel agricultural planting pattern to efficiently use local natural resources (e.g., water, land, sunshine, heat and fertilizer). It is widely promoted as a high yield system and can obtain considerable economic benefits, particularly in China. However, its environmental quality implication is not clear. In our study, Qianyanzhou station is famous for its stereoscopic agriculture pattern of Southern China, and an experimental watershed was selected as our study area. Regional characteristics of runoff and nitrogen losses were simulated by an integrated water system model (HEQM) with multi-objective calibration, and multiple agriculture practices were assessed to find the effective approach for the reduction of diffuse nitrogen losses. Results showed that daily variations of runoff and nitrogen forms were well reproduced throughout watershed, i.e., satisfactory performances for ammonium and nitrate nitrogen (NH4-N and NO3-N) loads, good performances for runoff and organic nitrogen (ON) load, and very good performance for total nitrogen (TN) load. The average loss coefficient was 62.74 kg/ha for NH4-N, 0.98 kg/ha for NO3-N, 0.0004 kg/ha for ON and 63.80 kg/ha for TN. The dominating form of nitrogen losses was NH4-N due to the applied fertilizers, and the most dramatic zones aggregated in the middle and downstream regions covered by paddy and orange orchard. In order to control diffuse nitrogen losses, the most effective practices for Qianyanzhou stereoscopic agriculture pattern were to reduce farmland planting scale in the valley by afforestation, particularly for orchard in the

  20. Solar cell modules with improved backskin and methods for forming same

    Science.gov (United States)

    Hanoka, Jack I.

    1998-04-21

    A laminated solar cell module with a backskin layer that reduces the materials and labor required during the manufacturing process. The solar cell module includes a rigid front support layer formed of light transmitting material having first and second surfaces. A transparent encapsulant layer has a first surface disposed adjacent the second surface of the front support layer. A plurality of interconnected solar cells have a first surface disposed adjacent a second surface of the transparent encapsulant layer. The backskin layer is formed of a thermoplastic olefin, which includes first ionomer, a second ionomer, glass fiber, and carbon black. A first surface of the backskin layer is disposed adjacent a second surface of the interconnected solar cells. The transparent encapsulant layer and the backskin layer, in combination, encapsulate the interconnected solar cells. An end portion of the backskin layer can be wrapped around the edge of the module for contacting the first surface of the front support layer to form an edge seal. A laminated solar cell module with a backskin layer that reduces the materials and labor required during the manufacturing process. The solar cell module includes a rigid front support layer formed of light transmitting material having first and second surfaces. A transparent encapsulant layer has a first surface disposed adjacent the second surface of the front support layer. A plurality of interconnected solar cells have a first surface disposed adjacent a second surface of the transparent encapsulant layer. The backskin layer is formed of a thermoplastic olefin, which includes first ionomer, a second ionomer, glass fiber, and carbon black. A first surface of the backskin layer is disposed adjacent a second surface of the interconnected solar cells. The transparent encapsulant layer and the backskin layer, in combination, encapsulate the interconnected solar cells. An end portion of the backskin layer can be wrapped around the edge of the

  1. Methods of generalizing and classifying layer structures of a special form

    Energy Technology Data Exchange (ETDEWEB)

    Viktorova, N P

    1981-09-01

    An examination is made of the problem of classifying structures represented by weighted multilayer graphs of special form with connections between the vertices of each layer. The classification of structures of such a form is based on the construction of resolving sets of graphs as a result of generalization of the elements of the training sample of each class and the testing of whether an input object is isomorphic (with allowance for the weights) to the structures of the resolving set or not. 4 references.

  2. Comparison of Pattern Classification Methods in Crossarm Reuse Judgement System Based on Rust Images

    Science.gov (United States)

    Yamana, Michiko; Murata, Hiroshi; Onoda, Takashi; Ohashi, Tohru; Kato, Seiji

    Japanese electric power companies currently utilize existing equipments completely and maintain facilities effectively. Human experts presently judge various hardwares whether they are be reusable or not to utilize equipments completely. Especially, this paper considers about crossarm reuse judgement. This judgement is based on rust, which attaches on crossarms, by human experts. However, this judgement depends on human expertise and it is difficult to keep constant judgement accuracy. Electric power companies want to take constant and good judgement accuracy. Therefore, we develop a crossarm reuse judgement system based on rust images using machine learning techniques. The system consists of commercial microscope and standard note PC to keep the cost. And we estimate the judgement accuracy of various pattern classification methods without the special image processing such as extracting features. The results show that support vector machine is the most suitable method for this judgement system.

  3. Two-dimensional chemically tunable patterns with cellular structures fabricated via thermal pressing method

    International Nuclear Information System (INIS)

    Wang Bo; Zhao Qinghe; Liu Lili; Gao Changyou; Han Kun; Zhang Junhu; Xiang Zheng; Yang Bai

    2006-01-01

    A novel and versatile soft lithography method, i.e. thermal pressing method has been established to create colloid arrays by using multilevel inks. Patterned poly(dimethylsiloxane) stamp containing silicone dioxide microparticles was pressed into a polycaprolactone (PCL) film at the temperature around the T m of PCL. Subsequent removal of the colloids left cavity arrays. By initially incorporating chitosan, albumin or CdTe quantum dots into the silicone dioxide microparticles, removal of the ordered SiO 2 microspheres would then release these substances which were stably embedded into the PCL matrices or suspended in the interiors of the cellular structures. By coating the SiO 2 microspheres with multilayers previously, thin covers on the cellular structures could be obtained after removal of the templates

  4. Specificity of Correlation Pattern Recognition Methods Application in Security Holograms Identity Control Apparatus

    Science.gov (United States)

    Zlokazov, E. Yu.; Starikov, R. S.; Odinokov, S. B.; Tsyganov, I. K.; Talalaev, V. E.; Koluchkin, V. V.

    Automatic inspection of security hologram (SH) identity is highly demanded issue due high distribution of SH worldwide to protect documents such as passports, driving licenses, banknotes etc. While most of the known approaches use inspection of SH design features none of these approaches inspect the features of its surface relief that is a direct contribution to original master matrix used for these holograms production. In our previous works we represented the device that was developed to provide SH identification by processing of coherent responses of its surface elements. Most of the algorithms used in this device are based on application of correlation pattern recognition methods. The main issue of the present article is a description of these methods application specificities.

  5. NMR and pattern recognition methods in metabolomics: From data acquisition to biomarker discovery: A review

    International Nuclear Information System (INIS)

    Smolinska, Agnieszka; Blanchet, Lionel; Buydens, Lutgarde M.C.; Wijmenga, Sybren S.

    2012-01-01

    Highlights: ► Procedures for acquisition of different biofluids by NMR. ► Recent developments in metabolic profiling of different biofluids by NMR are presented. ► The crucial steps involved in data preprocessing and multivariate chemometric analysis are reviewed. ► Emphasis is given on recent findings on Multiple Sclerosis via NMR and pattern recognition methods. - Abstract: Metabolomics is the discipline where endogenous and exogenous metabolites are assessed, identified and quantified in different biological samples. Metabolites are crucial components of biological system and highly informative about its functional state, due to their closeness to functional endpoints and to the organism's phenotypes. Nuclear Magnetic Resonance (NMR) spectroscopy, next to Mass Spectrometry (MS), is one of the main metabolomics analytical platforms. The technological developments in the field of NMR spectroscopy have enabled the identification and quantitative measurement of the many metabolites in a single sample of biofluids in a non-targeted and non-destructive manner. Combination of NMR spectra of biofluids and pattern recognition methods has driven forward the application of metabolomics in the field of biomarker discovery. The importance of metabolomics in diagnostics, e.g. in identifying biomarkers or defining pathological status, has been growing exponentially as evidenced by the number of published papers. In this review, we describe the developments in data acquisition and multivariate analysis of NMR-based metabolomics data, with particular emphasis on the metabolomics of Cerebrospinal Fluid (CSF) and biomarker discovery in Multiple Sclerosis (MScl).

  6. A new optimization method based on cellular automata for VVER-1000 nuclear reactor loading pattern

    International Nuclear Information System (INIS)

    Fadaei, Amir Hosein; Setayeshi, Saeed

    2009-01-01

    This paper presents a new and innovative optimization technique, which uses cellular automata for solving multi-objective optimization problems. Due to its ability in simulating the local information while taking neighboring effects into account, the cellular automata technique is a powerful tool for optimization. The fuel-loading pattern in nuclear reactor cores is a major optimization problem. Due to the immensity of the search space in fuel management optimization problems, finding the optimum solution requires a huge amount of calculations in the classical method. The cellular automata models, based on local information, can reduce the computations significantly. In this study, reducing the power peaking factor, while increasing the initial excess reactivity inside the reactor core of VVER-1000, which are two apparently contradictory objectives, are considered as the objective functions. The result is an optimum configuration, which is in agreement with the pattern proposed by the designer. In order to gain confidence in the reliability of this method, the aforementioned problem was also solved using neural network and simulated annealing, and the results and procedures were compared.

  7. Visual and Quantitative Analysis Methods of Respiratory Patterns for Respiratory Gated PET/CT.

    Science.gov (United States)

    Son, Hye Joo; Jeong, Young Jin; Yoon, Hyun Jin; Park, Jong-Hwan; Kang, Do-Young

    2016-01-01

    We integrated visual and quantitative methods for analyzing the stability of respiration using four methods: phase space diagrams, Fourier spectra, Poincaré maps, and Lyapunov exponents. Respiratory patterns of 139 patients were grouped based on the combination of the regularity of amplitude, period, and baseline positions. Visual grading was done by inspecting the shape of diagram and classified into two states: regular and irregular. Quantitation was done by measuring standard deviation of x and v coordinates of Poincaré map (SD x , SD v ) or the height of the fundamental peak ( A 1 ) in Fourier spectrum or calculating the difference between maximal upward and downward drift. Each group showed characteristic pattern on visual analysis. There was difference of quantitative parameters (SD x , SD v , A 1 , and MUD-MDD) among four groups (one way ANOVA, p = 0.0001 for MUD-MDD, SD x , and SD v , p = 0.0002 for A 1 ). In ROC analysis, the cutoff values were 0.11 for SD x (AUC: 0.982, p quantitative indices of respiratory stability and determining quantitative cutoff value for differentiating regular and irregular respiration.

  8. A Novel Unsupervised Adaptive Learning Method for Long-Term Electromyography (EMG) Pattern Recognition

    Science.gov (United States)

    Huang, Qi; Yang, Dapeng; Jiang, Li; Zhang, Huajie; Liu, Hong; Kotani, Kiyoshi

    2017-01-01

    Performance degradation will be caused by a variety of interfering factors for pattern recognition-based myoelectric control methods in the long term. This paper proposes an adaptive learning method with low computational cost to mitigate the effect in unsupervised adaptive learning scenarios. We presents a particle adaptive classifier (PAC), by constructing a particle adaptive learning strategy and universal incremental least square support vector classifier (LS-SVC). We compared PAC performance with incremental support vector classifier (ISVC) and non-adapting SVC (NSVC) in a long-term pattern recognition task in both unsupervised and supervised adaptive learning scenarios. Retraining time cost and recognition accuracy were compared by validating the classification performance on both simulated and realistic long-term EMG data. The classification results of realistic long-term EMG data showed that the PAC significantly decreased the performance degradation in unsupervised adaptive learning scenarios compared with NSVC (9.03% ± 2.23%, p < 0.05) and ISVC (13.38% ± 2.62%, p = 0.001), and reduced the retraining time cost compared with ISVC (2 ms per updating cycle vs. 50 ms per updating cycle). PMID:28608824

  9. A Novel Unsupervised Adaptive Learning Method for Long-Term Electromyography (EMG Pattern Recognition

    Directory of Open Access Journals (Sweden)

    Qi Huang

    2017-06-01

    Full Text Available Performance degradation will be caused by a variety of interfering factors for pattern recognition-based myoelectric control methods in the long term. This paper proposes an adaptive learning method with low computational cost to mitigate the effect in unsupervised adaptive learning scenarios. We presents a particle adaptive classifier (PAC, by constructing a particle adaptive learning strategy and universal incremental least square support vector classifier (LS-SVC. We compared PAC performance with incremental support vector classifier (ISVC and non-adapting SVC (NSVC in a long-term pattern recognition task in both unsupervised and supervised adaptive learning scenarios. Retraining time cost and recognition accuracy were compared by validating the classification performance on both simulated and realistic long-term EMG data. The classification results of realistic long-term EMG data showed that the PAC significantly decreased the performance degradation in unsupervised adaptive learning scenarios compared with NSVC (9.03% ± 2.23%, p < 0.05 and ISVC (13.38% ± 2.62%, p = 0.001, and reduced the retraining time cost compared with ISVC (2 ms per updating cycle vs. 50 ms per updating cycle.

  10. Validated UV-Spectrophotometric Methods for Determination of Gemifloxacin Mesylate in Pharmaceutical Tablet Dosage Forms

    Directory of Open Access Journals (Sweden)

    R. Rote Ambadas

    2010-01-01

    Full Text Available Two simple, economic and accurate UV spectrophotometric methods have been developed for determination of gemifloxacin mesylate in pharmaceutical tablet formulation. The first UV-spectrophotometric method depends upon the measurement of absorption at the wavelength 263.8 nm. In second area under curve method the wavelength range for detection was selected from 268.5-258.5 nm. Beer’s law was obeyed in the range of 2 to 12 μgmL-1 for both the methods. The proposed methods was validated statistically and applied successfully to determination of gemifloxacin mesylate in pharmaceutical formulation.

  11. Leveraging social and digital media for participant recruitment: A review of methods from the Bayley Short Form Formative Study

    OpenAIRE

    Burke-Garcia, Amelia; Mathew, Sunitha

    2017-01-01

    Introduction Social media is increasingly being used in research, including recruitment. Methods For the Bayley Short Form Formative Study, which was conducted under the the National Children’s Study, traditional methods of recruitment proved to be ineffective. Therefore, digital media were identified as potential channels for recruitment. Results Results included successful recruitment of over 1800 infant and toddler participants to the Study. Conclusions This paper outlines the methods, res...

  12. Feeding methods, sleep arrangement, and infant sleep patterns: a Chinese population-based study.

    Science.gov (United States)

    Huang, Xiao-Na; Wang, Hui-Shan; Chang, Jen-Jen; Wang, Lin-Hong; Liu, Xi-Cheng; Jiang, Jing-Xiong; An, Lin

    2016-02-01

    Findings from prior research into the effect of feeding methods on infant sleep are inconsistent. The objectives of this study were to examine infants' sleep patterns by feeding methods and sleep arrangement from birth to eight months old. This longitudinal cohort study enrolled 524 pregnant women at 34-41 weeks of gestation and their infants after delivery in 2006 and followed up until eight months postpartum. The study subjects were recruited from nine women and children hospitals in nine cities in China (Beijing, Chongqing, Wuhan, Changsha, Nanning, Xiamen, Xi'an, Jinan, and Hailin). Participating infants were followed up weekly during the first month and monthly from the second to the eighth month after birth. Twenty-four hour sleep diaries recording infants' sleeping and feeding methods were administered based on caregiver's self-report. Multivariable mixed growth curve models were fitted to estimate the effects of feeding methods and sleep arrangement on infants' sleep patterns over time, controlling for maternal and paternal age, maternal and paternal education level, household income, supplementation of complementary food, and infant birth weight and length. Exclusively formula fed infants had the greatest sleep percentage/24 h, followed by exclusively breast milk fed infants and partially breast milk fed infants (Psleep percentage and night waking frequency between exclusively formula and exclusively breast milk fed infants weakened over time as infants developed. In addition, compared to infants with bed-sharing sleep arrangement, those with room sharing sleep arrangement had greater daytime and 24-hour infant sleep percentage, whereas those with sleeping alone sleep arrangement had greater nighttime sleep percentage. Our data based on caregiver's self-report suggested that partial breastfeeding and bed-sharing may be associated with less sleep in infants. Health care professionals need to work with parents of newborns to develop coping strategies that

  13. Power Supply Interruption Costs: Models and Methods Incorporating Time Dependent Patterns

    International Nuclear Information System (INIS)

    Kjoelle, G.H.

    1996-12-01

    This doctoral thesis develops models and methods for estimation of annual interruption costs for delivery points, emphasizing the handling of time dependent patterns and uncertainties in the variables determining the annual costs. It presents an analytical method for calculation of annual expected interruption costs for delivery points in radial systems, based on a radial reliability model, with time dependent variables. And a similar method for meshed systems, based on a list of outage events, assuming that these events are found in advance from load flow and contingency analyses. A Monte Carlo simulation model is given which handles both time variations and stochastic variations in the input variables and is based on the same list of outage events. This general procedure for radial and meshed systems provides expectation values and probability distributions for interruption costs from delivery points. There is also a procedure for handling uncertainties in input variables by a fuzzy description, giving annual interruption costs as a fuzzy membership function. The methods are developed for practical applications in radial and meshed systems, based on available data from failure statistics, load registrations and customer surveys. Traditional reliability indices such as annual interruption time, power- and energy not supplied, are calculated as by-products. The methods are presented as algorithms and/or procedures which are available as prototypes. 97 refs., 114 figs., 62 tabs

  14. Power Supply Interruption Costs: Models and Methods Incorporating Time Dependent Patterns

    Energy Technology Data Exchange (ETDEWEB)

    Kjoelle, G.H.

    1996-12-01

    This doctoral thesis develops models and methods for estimation of annual interruption costs for delivery points, emphasizing the handling of time dependent patterns and uncertainties in the variables determining the annual costs. It presents an analytical method for calculation of annual expected interruption costs for delivery points in radial systems, based on a radial reliability model, with time dependent variables. And a similar method for meshed systems, based on a list of outage events, assuming that these events are found in advance from load flow and contingency analyses. A Monte Carlo simulation model is given which handles both time variations and stochastic variations in the input variables and is based on the same list of outage events. This general procedure for radial and meshed systems provides expectation values and probability distributions for interruption costs from delivery points. There is also a procedure for handling uncertainties in input variables by a fuzzy description, giving annual interruption costs as a fuzzy membership function. The methods are developed for practical applications in radial and meshed systems, based on available data from failure statistics, load registrations and customer surveys. Traditional reliability indices such as annual interruption time, power- and energy not supplied, are calculated as by-products. The methods are presented as algorithms and/or procedures which are available as prototypes. 97 refs., 114 figs., 62 tabs.

  15. Separating bathymetric data representing multiscale rhythmic bed forms : a geostatistical and spectral method compared

    NARCIS (Netherlands)

    van Dijk, Thaiënne A.G.P.; Lindenbergh, Roderik C.; Egberts, Paul J.P.

    2008-01-01

    The superimposition of rhythmic bed forms of different spatial scales is a common and natural phenomenon on sandy seabeds. The dynamics of such seabeds may interfere with different offshore activities and are therefore of interest to both scientists and offshore developers. State-of-the-art echo

  16. Effect of Bottoming on Material Property during Sheet Forming Process through Finite Element Method

    Science.gov (United States)

    Akinlabi, Stephen A.; Fatoba, Olawale S.; Mashinini, Peter M.; Akinlabi, Esther T.

    2018-03-01

    Metal forming is one of the conventional manufacturing processes of immense relevance till date even though modern manufacturing processes have evolved over the years. It is a known fact that material tends to return or spring back to its original form during forming or bending. The phenomena have been well managed through its application in various manufacturing processes by compensating for the spring back through overbending and bottoming. Overbending is bending the material beyond the desired shape to allow the material to spring back to the expected shape. Bottoming, on the other hand, is a process of undergoing plastic deformation at the point of bending. This study reports on the finite element analysis of the effect of bottoming on the material property during the sheet forming process with the aim of optimising the process. The result of the analysis revealed that the generated plastic strains are in the order between 1.750e00-1 at the peak of the bending and 3.604e00-2, which was at the early stage of the bending.

  17. The Optimal Conditions for Form-Focused Instruction: Method, Target Complexity, and Types of Knowledge

    Science.gov (United States)

    Kim, Jeong-eun

    2012-01-01

    This dissertation investigates optimal conditions for form-focused instruction (FFI) by considering effects of internal (i.e., timing and types of FFI) and external (i.e., complexity and familiarity) variables of FFI when it is offered within a primarily meaning-focused context of adult second language (L2) learning. Ninety-two Korean-speaking…

  18. Current algebra method for form factors and strong decays with hard pions and kaons

    International Nuclear Information System (INIS)

    Srivastava, P.P.

    1969-01-01

    The F K /F Π ratio between the kaon and pion decay couplings in one lepton pair, sum rules for Weinberg spectral functions, form factor renormalization of the K l3 decay because of the SU(3) symmetry violation and the calculations of strong decays of the K* and K A strange resonances are presented and discussed. (L.C.) [pt

  19. Adaptive Sampling based 3D Profile Measuring Method for Free-Form Surface

    Science.gov (United States)

    Duan, Xianyin; Zou, Yu; Gao, Qiang; Peng, Fangyu; Zhou, Min; Jiang, Guozhang

    2018-03-01

    In order to solve the problem of adaptability and scanning efficiency of the current surface profile detection device, a high precision and high efficiency detection approach is proposed for surface contour of free-form surface parts based on self- adaptability. The contact mechanical probe and the non-contact laser probe are synthetically integrated according to the sampling approach of adaptive front-end path detection. First, the front-end path is measured by the non-contact laser probe, and the detection path is planned by the internal algorithm of the measuring instrument. Then a reasonable measurement sampling is completed according to the planned path by the contact mechanical probe. The detection approach can effectively improve the measurement efficiency of the free-form surface contours and can simultaneously detect the surface contours of unknown free-form surfaces with different curvatures and even different rate of curvature. The detection approach proposed in this paper also has important reference value for free-form surface contour detection.

  20. Forming method of a functional layer-built film by micro-wave plasma CVD

    Energy Technology Data Exchange (ETDEWEB)

    Saito, Keishi

    1988-11-18

    In forming an amorphous semi-conductor material film, the micro-wave plasma CVD cannot be generally used because of such demerits as film-separation, low yield, columnar structure in the film, and problems in the optical and electrical properties. In this invention, a specific substrate is placed in a layer-built film forming unit which is capable of maintaining vacuum; raw material gas for the film formation is introduced; plasma is generated by a micro-wave energy to decompose the raw material gas, thus forming the layer-built film on the substarte. Then a film is made by adding a specific amount of calcoganide-containing gas to the raw material gas. By this, the utilization efficiency of the raw material gas gets roughly 100% and both the adhesion to the substrate and the structural flexibility of the layer-built film increase, enhancing the yield of forming various functional elements (sensor, solar cell, thin transistor film, etc.), and thus greatly reducing the production cost. 6 figs., 7 tabs.

  1. Investigation into complexing of pentavalent actinide forms with some anions of organic acids by the coprecipitation method

    International Nuclear Information System (INIS)

    Moskvin, A.I.; Poznyakov, A.N.; AN SSSR, Moscow. Inst. Geokhimii i Analiticheskoj Khimii)

    1979-01-01

    Complexing of pentavolent forms of Np, Pu, Am actinides with anions of acetic, oxalic acids and EDTA is studied using the method of coprecipitation with iron hydroxide. Composition and stability constants of the actinide complexes formed are determined. The acids anions are arranged in a row in the order of decrease of complexing tendency that is EDTA anion>C 2 O 4 2- >CH 3 COO -

  2. Composite media for fluid stream processing, a method of forming the composite media, and a related method of processing a fluid stream

    Science.gov (United States)

    Garn, Troy G; Law, Jack D; Greenhalgh, Mitchell R; Tranter, Rhonda

    2014-04-01

    A composite media including at least one crystalline aluminosilicate material in polyacrylonitrile. A method of forming a composite media is also disclosed. The method comprises dissolving polyacrylonitrile in an organic solvent to form a matrix solution. At least one crystalline aluminosilicate material is combined with the matrix solution to form a composite media solution. The organic solvent present in the composite media solution is diluted. The composite media solution is solidified. In addition, a method of processing a fluid stream is disclosed. The method comprises providing a beads of a composite media comprising at least one crystalline aluminosilicate material dispersed in a polyacrylonitrile matrix. The beads of the composite media are contacted with a fluid stream comprising at least one constituent. The at least one constituent is substantially removed from the fluid stream.

  3. Method of forming magnetostrictive rods from rare earth-iron alloys

    Science.gov (United States)

    McMasters, O. Dale

    1986-09-02

    Rods of magnetrostructive alloys of iron with rare earth elements are formed by flowing a body of rare earth-iron alloy in a crucible enclosed in a chamber maintained under an inert gas atmosphere, forcing such molten rare-earth-iron alloy into a hollow mold tube of refractory material positioned with its lower end portion within the molten body by means of a pressure differential between the chamber and mold tube and maintaining a portion of the molten alloy in the crucible extending to a level above the lower end of the mold tube so that solid particles of higher melting impurities present in the alloy collect at the surface of the molten body and remain within the crucible as the rod is formed in the mold tube.

  4. FORMATION OF COMMUNICATIVE COMPETENCE AS METHOD OF FORMING PROFESSIONALISM OF FUTURE TUTORS OF PRESCHOOL INSTITUTIONS

    Directory of Open Access Journals (Sweden)

    Karyna Savchenko

    2016-06-01

    Full Text Available In article problems of forming of communicative competence of future teachers are considered. The concept communicative competence is considered, communication of communicative competence with professional is shown. Implementation of subject role plays on forming of communicative competence of future specialists of the higher school is shown. In modern conditions the need for people who have gained professional knowledge which uses masterfully culture of speech communication and capable to address in a native and foreign language is rather sharply felt. Successful implementation of ideas of programs to a large extent depends on the teacher, the level of its professionalism. Cardinal reforming of life of society has created real prerequisites for considerable transformations in economy, culture, science, there are against global integration into world educational space, growth of a role of ethnic cultural factors and national consciousness, essential increase of requirements to professional competence of specialists, upgrades of an education system

  5. Comparison of various methods of measuring thin oxide layers formed on molybdenum and titanium

    International Nuclear Information System (INIS)

    Lepage, F.; Bardolle, J.; Boulben, J.M.

    1975-01-01

    The problem of the growth of thin layers is very interesting from both the fundamental and technological viewpoints. This work deals with oxide films produced on two metals, molybdenum and titanium. The thicknesses obtained by various methods (microgravimetry, nuclear reactions and spectrophotometry) are compared and the advantages and disadvantages of each method are shown [fr

  6. A new form of MgTa2O6 obtained by the molten salt method

    Indian Academy of Sciences (India)

    Unknown

    Abstract. Using molten salt route (with NaCl/KCl as the salt) we have been able to synthesize a new form of magnesium tantalate at 850°C. Powder X-ray diffraction data could be indexed on an orthorhombic unit cell with lattice parameters, 'a' = 15⋅36(1) Å, 'b' = 13⋅38(1) Å and 'c' = 12⋅10(1) Å. High resolution.

  7. Estimating the carbohydrate content of various forms of tobacco by phenol-sulfuric acid method

    OpenAIRE

    Jain, Vardhaman Mulchand; Karibasappa, Gundabaktha Nagappa; Dodamani, Arun Suresh; Mali, Gaurao Vasant

    2017-01-01

    BACKGROUND: Due to consumption of various forms of tobacco in large amounts by Indian population, it has become a cause of concern for major oral diseases. In 2008, the WHO named tobacco as the world's single greatest cause of preventable death. It is also known that certain amount of carbohydrates are incorporated in processed tobacco to make it acceptable for consumption. Thus, its role in oral diseases becomes an important question at this point of time. Through this study, it is attempted...

  8. Phase boundary estimation in electrical impedance tomography using the Hooke and Jeeves pattern search method

    International Nuclear Information System (INIS)

    Khambampati, Anil Kumar; Kim, Kyung Youn; Ijaz, Umer Zeeshan; Lee, Jeong Seong; Kim, Sin

    2010-01-01

    In industrial processes, monitoring of heterogeneous phases is crucial to the safety and operation of the engineering structures. Particularly, the visualization of voids and air bubbles is advantageous. As a result many studies have appeared in the literature that offer varying degrees of functionality. Electrical impedance tomography (EIT) has already been proved to be a hallmark for process monitoring and offers not only the visualization of the resistivity profile for a given flow mixture but is also used for detection of phase boundaries. Iterative image reconstruction algorithms, such as the modified Newton–Raphson (mNR) method, are commonly used as inverse solvers. However, their utility is problematic in a sense that they require the initial solution in close proximity of the ground truth. Furthermore, they also rely on the gradient information of the objective function to be minimized. Therefore, in this paper, we address all these issues by employing a direct search algorithm, namely the Hooke and Jeeves pattern search method, to estimate the phase boundaries that directly minimizes the cost function and does not require the gradient information. It is assumed that the resistivity profile is known a priori and therefore the unknown information will be the size and location of the object. The boundary coefficients are parameterized using truncated Fourier series and are estimated using the relationship between the measured voltages and injected currents. Through extensive simulation and experimental result and by comparison with mNR, we show that the Hooke and Jeeves pattern search method offers a promising prospect for process monitoring

  9. Dependent data in social sciences research forms, issues, and methods of analysis

    CERN Document Server

    Eye, Alexander; Wiedermann, Wolfgang

    2015-01-01

    This volume presents contributions on handling data in which the postulate of independence in the data matrix is violated. When this postulate is violated and when the methods assuming independence are still applied, the estimated parameters are likely to be biased, and statistical decisions are very likely to be incorrect. Problems associated with dependence in data have been known for a long time, and led to the development of tailored methods for the analysis of dependent data in various areas of statistical analysis. These methods include, for example, methods for the analysis of longitudinal data, corrections for dependency, and corrections for degrees of freedom. This volume contains the following five sections: growth curve modeling, directional dependence, dyadic data modeling, item response modeling (IRT), and other methods for the analysis of dependent data (e.g., approaches for modeling cross-section dependence, multidimensional scaling techniques, and mixed models). Researchers and graduate stud...

  10. Granulometric analysis of metallic oxide in ceramic powder form synthesized by different methods

    International Nuclear Information System (INIS)

    Neiva, L.S.; Simoes, A.N.; Simoes, V.N.; Bispo, A.; Gama, L.

    2012-01-01

    The aim of this work is to synthesize ceramic powders based on CuO/CeO 2 by means two different synthesis methods, they are: the combustion reaction method and Pechini method. It's part of the aim of this work subject all samples to a synthesized qualitative and quantitative chemical analysis, using the technique EDX and then to a granulometric analysis. The samples of the ceramic powder based on CuO/CeO 2 synthesized in this work by means of the two above synthesis methods, contain various concentrations of CuO ranging between 0 and 0.5 mol. According to the results, only the Pechini method of synthesis exerted a significant and defined influence on the capacity of particle unit agglomeration in these powders (author)

  11. Discrete element method (DEM) simulations of stratified sampling during solid dosage form manufacturing.

    Science.gov (United States)

    Hancock, Bruno C; Ketterhagen, William R

    2011-10-14

    Discrete element model (DEM) simulations of the discharge of powders from hoppers under gravity were analyzed to provide estimates of dosage form content uniformity during the manufacture of solid dosage forms (tablets and capsules). For a system that exhibits moderate segregation the effects of sample size, number, and location within the batch were determined. The various sampling approaches were compared to current best-practices for sampling described in the Product Quality Research Institute (PQRI) Blend Uniformity Working Group (BUWG) guidelines. Sampling uniformly across the discharge process gave the most accurate results with respect to identifying segregation trends. Sigmoidal sampling (as recommended in the PQRI BUWG guidelines) tended to overestimate potential segregation issues, whereas truncated sampling (common in industrial practice) tended to underestimate them. The size of the sample had a major effect on the absolute potency RSD. The number of sampling locations (10 vs. 20) had very little effect on the trends in the data, and the number of samples analyzed at each location (1 vs. 3 vs. 7) had only a small effect for the sampling conditions examined. The results of this work provide greater understanding of the effect of different sampling approaches on the measured content uniformity of real dosage forms, and can help to guide the choice of appropriate sampling protocols. Copyright © 2011 Elsevier B.V. All rights reserved.

  12. Method for explosive expansion toward horizontal free faces for forming an in situ oil shale retort

    Science.gov (United States)

    Ricketts, Thomas E.

    1980-01-01

    Formation is excavated from within a retort site in formation containing oil shale for forming a plurality of vertically spaced apart voids extending horizontally across different levels of the retort site, leaving a separate zone of unfragmented formation between each pair of adjacent voids. Explosive is placed in each zone, and such explosive is detonated in a single round for forming an in situ retort containing a fragmented permeable mass of formation particles containing oil shale. The same amount of formation is explosively expanded upwardly and downwardly toward each void. A horizontal void excavated at a production level has a smaller horizontal cross-sectional area than a void excavated at a lower level of the retort site immediately above the production level void. Explosive in a first group of vertical blast holes is detonated for explosively expanding formation downwardly toward the lower void, and explosive in a second group of vertical blast holes is detonated in the same round for explosively expanding formation upwardly toward the lower void and downwardly toward the production level void for forming a generally T-shaped bottom of the fragmented mass.

  13. Developing and setting up optical methods to study the speckle patterns created by optical beam smoothing

    International Nuclear Information System (INIS)

    Surville, J.

    2005-12-01

    We have developed three main optical methods to study the speckles generated by a smoothed laser source. The first method addresses the measurement of the temporal and spatial correlation functions of the source, with a modified Michelson interferometer. The second one is a pump-probe technique created to shoot a picture of a speckle pattern generated at a set time. And the third one is an evolution of the second method dedicated to time-frequency coding, thanks to a frequency chirped probe pulse. Thus, the speckles can be followed in time and their motion can be described. According to these three methods, the average size and duration of the speckles can be measured. It is also possible to measure the size and the duration of each of them and mostly their velocity in a given direction. All the results obtained have been confronted to the different existing theories. We show that the statistical distributions of the measured speckles'size and speckles'intensity agree satisfactorily with theoretical values

  14. A Study of Method Development, Validation, and Forced Degradation for Simultaneous Quantification of Paracetamol and Ibuprofen in Pharmaceutical Dosage Form by RP-HPLC Method

    OpenAIRE

    Jahan, Md. Sarowar; Islam, Md. Jahirul; Begum, Rehana; Kayesh, Ruhul; Rahman, Asma

    2014-01-01

    A rapid and stability-indicating reversed phase high-performance liquid chromatography (RP-HPLC) method was developed for simultaneous quantification of paracetamol and ibuprofen in their combined dosage form especially to get some more advantages over other methods already developed for this combination. The method was validated according to United States Pharmacopeia (USP) guideline with respect to accuracy, precision, specificity, linearity, solution stability, robustness, sensitivity, and...

  15. UV Spectrophotometric Method for Determination of Cinitapride in Pure and its Solid Dosage Form

    Directory of Open Access Journals (Sweden)

    B. Thangabalan

    2009-01-01

    Full Text Available A new, rapid, precise, accurate and sensitive analytical method was developed for the UV spectrophotometric assay of cinitapride (CTP. The drug obeyed the Beer's law and showed good correlation. It showed absorption maxima at 260 nm in methanol. The linearity was observed between 5-40 µg mL-1. The results of analysis were validated by recovery studies. The recovery was more than 99%. The proposed method is the only method available for spectrophotometric determination of the drug. It is simple, precise, sensitive and reproducible and can be used for the routine quality control testing of the marketed formulations.

  16. Influence of postnatal glucocorticoids on hippocampal-dependent learning varies with elevation patterns and administration methods.

    Science.gov (United States)

    Claflin, Dragana I; Schmidt, Kevin D; Vallandingham, Zachary D; Kraszpulski, Michal; Hennessy, Michael B

    2017-09-01

    Recent interest in the lasting effects of early-life stress has expanded to include effects on cognitive performance. An increase in circulating glucocorticoids is induced by stress exposure and glucocorticoid effects on the hippocampus likely underlie many of the cognitive consequences. Here we review studies showing that corticosterone administered to young rats at the conclusion of the stress-hyporesponsiveness period affects later performance in hippocampally-mediated trace eyeblink conditioning. The nature and even direction of these effects varies with the elevation patterns (level, duration, temporal fluctuation) achieved by different administration methods. We present new time course data indicating that constant glucocorticoid elevations generally corresponded with hippocampus-mediated learning deficits, whereas acute, cyclical elevations corresponded with improved initial acquisition. Sensitivity was greater for males than for females. Further, changes in hippocampal neurogenesis paralleled some but not all effects. The findings demonstrate that specific patterns of glucocorticoid elevation produced by different drug administration procedures can have markedly different, sex-specific consequences on basic cognitive performance and underlying hippocampal physiology. Implications of these findings for glucocorticoid medications prescribed in childhood are discussed. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Simple and Inexpensive Methods Development for Determination of Venlafaxine Hydrochloride from Its Solid Dosage Forms by Visible Spectrophotometry

    Directory of Open Access Journals (Sweden)

    K. Raghubabu

    2012-01-01

    Full Text Available Two simple, sensitive and cost effective visible spectrophotometric methods (M1 and M2 have been developed for the determination of venlafaxine hydrochloride from bulk and tablet dosage forms. The method M1 is based on the formation of green colored coordination complex by the drug with cobalt thiocyanate which is quantitatively extractable into nitro benzene with an absorption maximum of 626.4 nm. The method M2 involves internal salt formation of aconitic anhydride, dehydration product of citric acid [CIA] with acetic anhydride [Ac2O] to form colored chromogen with an absorption maximum of 561.2 nm. The calibration graph is linear over the concentration range of 10-50 µg/mL and 8-24 µg/mL for method M1 and M2 respectively. The proposed methods are applied to commercial available tablets and the results are statistically compared with those obtained by the reference method and validated by recovery studies. The results are found satisfactory and reproducible. These methods are applied successfully for the estimation of the venlafaxine hydrochloride in the presence of other ingredients that are usually present in dosage forms.

  18. GC Method Validation for the Analysis of Menthol in Suppository Pharmaceutical Dosage Form

    Directory of Open Access Journals (Sweden)

    Murad N. Abualhasan

    2017-01-01

    Full Text Available Menthol is widely used as a fragrance and flavor in the food and cosmetic industries. It is also used in the medical and pharmaceutical fields for its various biological effects. Gas chromatography (GC is considered to be a sensitive method for the analysis of menthol. GC chromatographic separation was developed using capillary column (VF-624 and a flame ionization detector (FID. The method was validated as per ICH guidelines for various parameters such as precision, linearity, accuracy, solution stability, robustness, limit of detection, and quantification. The tested validation parameters were found to be within acceptable limits. The method was successfully applied for the quantification of menthol in suppositories formulations. Quality control departments and official pharmacopeias can use our developed method in the analysis of menthol in pharmaceutical dosage formulation and raw material.

  19. Conventional methods fail to measure cp(omega) of glass-forming liquids

    DEFF Research Database (Denmark)

    Christensen, Tage Emil; Olsen, Niels Boye; Dyre, Jeppe

    2007-01-01

    thermal-wave method does not measure the isobaric frequency-dependent specific heat cp(omega). This method rather measures a "longitudinal" frequency-dependent specific heat, a quantity defined and detailed here that is in between cp(omega) and cV(omega). This result means that no reliable wide......-frequency measurements of cp(omega) on liquids approaching the calorimetric glass transition exist. We briefly discuss consequences for experiment....

  20. New Methods for B Decay Constants and Form Factors from Lattice NRQCD

    Energy Technology Data Exchange (ETDEWEB)

    Davies, Christine [Glasgow U.; Hughes, Ciaran [Cambridge U., DAMTP; Monahan, Christopher [Rutgers U., Piscataway

    2018-01-01

    We determine the normalisation of scalar and pseudo scalar current operators made from NonRelativistic QCD (NRQCD) b quarks and Highly Improved Staggered (HISQ) light quarks through O(αs∧QCD/mb). We use matrix elements of these operators to extract B meson decay constants and form factors and compare to those obtained using the standard vector and axial vector operators. We work on MILC second-generation 2+1+1 gluon field configurations, including those with physical light quarks in the sea. This provides a test of systematic uncertainties in these calculations and we find agreement between the results to the 2% level of uncertainty previously quoted.