Calculus of Elementary Functions, Part II. Student Text. Revised Edition.

Science.gov (United States)

Herriot, Sarah T.; And Others

This course is intended for students who have a thorough knowledge of college preparatory mathematics, including algebra, axiomatic geometry, trigonometry, and analytic geometry. This text, Part II, contains material designed to follow Part I. Chapters included in this text are: (6) Derivatives of Exponential and Related Functions; (7) Area and…

Nursing Care of Patients Undergoing Chemotherapy Desensitization: Part II.

Science.gov (United States)

Jakel, Patricia; Carsten, Cynthia; Carino, Arvie; Braskett, Melinda

2016-04-01

Chemotherapy desensitization protocols are safe, but labor-intensive, processes that allow patients with cancer to receive medications even if they initially experienced severe hypersensitivity reactions. Part I of this column discussed the pathophysiology of hypersensitivity reactions and described the development of desensitization protocols in oncology settings. Part II incorporates the experiences of an academic medical center and provides a practical guide for the nursing care of patients undergoing chemotherapy desensitization.
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40 CFR Appendix II to Part 1054 - Duty Cycles for Laboratory Testing

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Duty Cycles for Laboratory Testing II.... 1054, App. II Appendix II to Part 1054—Duty Cycles for Laboratory Testing (a) Test handheld engines with the following steady-state duty cycle: G3 mode No. Engine speed a Torque(percent) b Weighting...

40 CFR Appendix II to Part 1039 - Steady-State Duty Cycles

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Steady-State Duty Cycles II Appendix... Appendix II to Part 1039—Steady-State Duty Cycles (a) The following duty cycles apply for constant-speed engines: (1) The following duty cycle applies for discrete-mode testing: D2 mode number Engine speed...

First international 26Al interlaboratory comparison - Part II

International Nuclear Information System (INIS)

Merchel, Silke; Bremser, Wolfram

2005-01-01

After finishing Part I of the first international 26 Al interlaboratory comparison with accelerator mass spectrometry (AMS) laboratories [S. Merchel, W. Bremser, Nucl. Instr. and Meth. B 223-224 (2004) 393], the evaluation of Part II with radionuclide counting laboratories took place. The evaluation of the results of the seven participating laboratories on four meteorite samples shows a good overall agreement between laboratories, i.e. it does not reveal any statistically significant differences if results are compared sample-by-sample. However, certain interlaboratory bias is observed with a more detailed statistical analysis including some multivariate approaches

Programming Models for Three-Dimensional Hydrodynamics on the CM-5 (Part II)

International Nuclear Information System (INIS)

Amala, P.A.K.; Rodrigue, G.H.

1994-01-01

This is a two-part presentation of a timing study on the Thinking Machines CORP. CM-5 computer. Part II is given in this study and represents domain-decomposition and message-passing models. Part I described computational problems using a SIMD model and connection machine FORTRAN (CMF)

Continuum Thermodynamics - Part II: Applications and Examples

Science.gov (United States)

Albers, Bettina; Wilmanski, Krzysztof

The intention by writing Part II of the book on continuum thermodynamics was the deepening of some issues covered in Part I as well as a development of certain skills in dealing with practical problems of oscopic processes. However, the main motivation for this part is the presentation of main facets of thermodynamics which appear when interdisciplinary problems are considered. There are many monographs on the subjects of solid mechanics and thermomechanics, on fluid mechanics and on coupled fields but most of them cover only special problems in great details which are characteristic for the chosen field. It is rather seldom that relations between these fields are discussed. This concerns, for instance, large deformations of the skeleton of porous materials with diffusion (e.g. lungs), couplings of deformable particles with the fluid motion in suspensions, couplings of adsorption processes and chemical reactions in immiscible mixtures with diffusion, various multi-component aspects of the motion, e.g. of avalanches, such as segregation processes, etc...

Benchmark matrix and guide: Part II.

Science.gov (United States)

1991-01-01

In the last issue of the Journal of Quality Assurance (September/October 1991, Volume 13, Number 5, pp. 14-19), the benchmark matrix developed by Headquarters Air Force Logistics Command was published. Five horizontal levels on the matrix delineate progress in TQM: business as usual, initiation, implementation, expansion, and integration. The six vertical categories that are critical to the success of TQM are leadership, structure, training, recognition, process improvement, and customer focus. In this issue, "Benchmark Matrix and Guide: Part II" will show specifically how to apply the categories of leadership, structure, and training to the benchmark matrix progress levels. At the intersection of each category and level, specific behavior objectives are listed with supporting behaviors and guidelines. Some categories will have objectives that are relatively easy to accomplish, allowing quick progress from one level to the next. Other categories will take considerable time and effort to complete. In the next issue, Part III of this series will focus on recognition, process improvement, and customer focus.

12 CFR Appendix II to Part 27 - Information for Government Monitoring Purposes

Science.gov (United States)

2010-01-01

... II Appendix II to Part 27 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY... Monitoring Purposes The following language is approved by the Comptroller of the Currency and will satisfy... used separately. This information may also be provided orally by the applicant. The following...

31 CFR Appendix II to Part 13 - Form of Bill for Reimbursement

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Form of Bill for Reimbursement II Appendix II to Part 13 Money and Finance: Treasury Office of the Secretary of the Treasury PROCEDURES FOR... title) of ______ (Country) to participate in the work of ______ (International Organization) or...

Tobacco control and gender in south-east Asia. Part II: Singapore and Vietnam.

Science.gov (United States)

Morrow, Martha; Barraclough, Simon

2003-12-01

In the World Health Organization's Western Pacific Region, being born male is the single greatest risk marker for tobacco use. While the literature demonstrates that risks associated with tobacco use may vary according to sex, gender refers to the socially determined roles and responsibilities of men and women, who initiate, continue and quit using tobacco for complex and often different reasons. Cigarette advertising frequently appeals to gender roles. Yet tobacco control policy tends to be gender-blind. Using a broad, gender-sensitivity framework, this contradiction is explored in four Western Pacific countries. Part I of the study presented the rationale, methodology and design of the study, discussed issues surrounding gender and tobacco, and analysed developments in Malaysia and the Philippines (see the previous issue of this journal). Part II deals with Singapore and Vietnam. In all four countries gender was salient for the initiation and maintenance of smoking. Yet, with a few exceptions, gender was largely unrecognized in control policy. Suggestions for overcoming this weakness in order to enhance tobacco control are made.

10 CFR Appendix II to Part 1050 - DOE Form 3735.3-Foreign Travel Statement

Science.gov (United States)

2010-01-01

... is official agency business. Spouses and dependents may accept such travel and expenses only when... 10 Energy 4 2010-01-01 2010-01-01 false DOE Form 3735.3-Foreign Travel Statement II Appendix II to.... II Appendix II to Part 1050—DOE Form 3735.3—Foreign Travel Statement EC01OC91.041 Statement...

A Survey of Optometry Graduates to Determine Practice Patterns: Part II: Licensure and Practice Establishment Experiences.

Science.gov (United States)

Bleimann, Robert L.; Smith, Lee W.

1985-01-01

A summary of Part II of a two-volume study of optometry graduates conducted by the Association of Schools and Colleges of Optometry is presented. Part II includes the analysis of the graduates' licensure and practice establishment experiences. (MLW)

Healing and relaxation in flows of helium II. Part II. First, second, and fourth sound

International Nuclear Information System (INIS)

Hills, R.N.; Roberts, P.H.

1978-01-01

In Part I of this series, a theory of helium II incorporating the effects of quantum healing and relaxation was developed. In this paper, the propagation of first, second, and fourth sound is discussed. Particular attention is paid to sound propagation in the vicinity of the lambda point where the effects of relaxation and quantum healing become important

Blade System Design Study. Part II, final project report (GEC).

Energy Technology Data Exchange (ETDEWEB)

Griffin, Dayton A. (DNV Global Energy Concepts Inc., Seattle, WA)

2009-05-01

As part of the U.S. Department of Energy's Low Wind Speed Turbine program, Global Energy Concepts LLC (GEC)1 has studied alternative composite materials for wind turbine blades in the multi-megawatt size range. This work in one of the Blade System Design Studies (BSDS) funded through Sandia National Laboratories. The BSDS program was conducted in two phases. In the Part I BSDS, GEC assessed candidate innovations in composite materials, manufacturing processes, and structural configurations. GEC also made recommendations for testing composite coupons, details, assemblies, and blade substructures to be carried out in the Part II study (BSDS-II). The BSDS-II contract period began in May 2003, and testing was initiated in June 2004. The current report summarizes the results from the BSDS-II test program. Composite materials evaluated include carbon fiber in both pre-impregnated and vacuum-assisted resin transfer molding (VARTM) forms. Initial thin-coupon static testing included a wide range of parameters, including variation in manufacturer, fiber tow size, fabric architecture, and resin type. A smaller set of these materials and process types was also evaluated in thin-coupon fatigue testing, and in ply-drop and ply-transition panels. The majority of materials used epoxy resin, with vinyl ester (VE) resin also used for selected cases. Late in the project, testing of unidirectional fiberglass was added to provide an updated baseline against which to evaluate the carbon material performance. Numerous unidirectional carbon fabrics were considered for evaluation with VARTM infusion. All but one fabric style considered suffered either from poor infusibility or waviness of fibers combined with poor compaction. The exception was a triaxial carbon-fiberglass fabric produced by SAERTEX. This fabric became the primary choice for infused articles throughout the test program. The generally positive results obtained in this program for the SAERTEX material have led to its

The Mid America Heart Institute: part II.

Science.gov (United States)

McCallister, Ben D; Steinhaus, David M

2003-01-01

The Mid America Heart Institute (MAHI) is one of the first and largest hospitals developed and designed specifically for cardiovascular care. The MAHI hybrid model, which is a partnership between the not-for-profit Saint Luke's Health System, an independent academic medical center, and a private practice physician group, has been extremely successful in providing high-quality patient care as well as developing strong educational and research programs. The Heart Institute has been the leader in providing cardiovascular care in the Kansas City region since its inception in 1975. Although challenges in the future are substantial, it is felt that the MAHI is in an excellent position to deal with the serious issues in health care because of the Heart Institute, its facility, organization, administration, dedicated medical and support staff, and its unique business model of physician management. In part I, the authors described the background and infrastructure of the Heart Institute. In part II, cardiovascular research and benefits of physician management are addressed.

Marketing in the E-Business World, Parts I & II | Smith | LBS ...

African Journals Online (AJOL)

Marketing in the E-Business World, Parts I & II. ... Open Access DOWNLOAD FULL TEXT ... of many of Americas largest companies gather at the Waldorf Astoria Hotel in New York City for the Conference Boards Annual Marketing Conference.

40 CFR Appendix II to Part 1045 - Duty Cycles for Propulsion Marine Engines

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Duty Cycles for Propulsion Marine... Pt. 1045, App. II Appendix II to Part 1045—Duty Cycles for Propulsion Marine Engines (a) The following duty cycle applies for discrete-mode testing: E4 Mode No. Enginespeed 1 Torque(percent) 2...

Methods of humidity determination Part II: Determination of material humidity

OpenAIRE

Rübner, Katrin; Balköse, Devrim; Robens, E.

2008-01-01

Part II covers the most common methods of measuring the humidity of solid material. State of water near solid surfaces, gravimetric measurement of material humidity, measurement of water sorption isotherms, chemical methods for determination of water content, measurement of material humidity via the gas phase, standardisation, cosmonautical observations are reviewed.

The year 2012 in the European Heart Journal-Cardiovascular Imaging. Part II.

Science.gov (United States)

Plein, Sven; Knuuti, Juhani; Edvardsen, Thor; Saraste, Antti; Piérard, Luc A; Maurer, Gerald; Lancellotti, Patrizio

2013-07-01

The part II of the best of the European Heart Journal - Cardiovascular Imaging in 2012 specifically focuses on studies of valvular heart diseases, heart failure, cardiomyopathies, and congenital heart diseases.

On the Efficiency of Connection Charges---Part II: Integration of Distributed Energy Resources

OpenAIRE

Munoz-Alvarez, Daniel; Garcia-Franco, Juan F.; Tong, Lang

2017-01-01

This two-part paper addresses the design of retail electricity tariffs for distribution systems with distributed energy resources (DERs). Part I presents a framework to optimize an ex-ante two-part tariff for a regulated monopolistic retailer who faces stochastic wholesale prices on the one hand and stochastic demand on the other. In Part II, the integration of DERs is addressed by analyzing their endogenous effect on the optimal two-part tariff and the induced welfare gains. Two DER integrat...

Instrumentation: Photodiode Array Detectors in UV-VIS Spectroscopy. Part II.

Science.gov (United States)

Jones, Dianna G.

1985-01-01

A previous part (Analytical Chemistry; v57 n9 p1057A) discussed the theoretical aspects of diode ultraviolet-visual (UV-VIS) spectroscopy. This part describes the applications of diode arrays in analytical chemistry, also considering spectroelectrochemistry, high performance liquid chromatography (HPLC), HPLC data processing, stopped flow, and…

Subseabed disposal program annual report, January-December 1979. Volume II. Appendices (principal investigator progress reports). Part 2 of 2

International Nuclear Information System (INIS)

Talbert, D.M.

1981-04-01

Volume II of the sixth annual report describing the progress and evaluating the status of the Subseabed Disposal Program contains the appendices referred to in Volume II, Summary and Status. Because of the length of Volume II, it has been split into two parts for publication purposes. Part 1 contains Appendices A-O; Part 2 contains Appendices P-FF. Separate abstracts have been prepared for each appendix for inclusion in the Energy Data Base

Subseabed disposal program annual report, January-December 1980. Volume II. Appendices (principal investigator progress reports). Part 1

International Nuclear Information System (INIS)

Hinga, K.R.

1981-07-01

Volume II of the sixth annual report describing the progress and evaluating the status of the Subseabed Disposal Program contains the appendices referred to in Volume I, Summary and Status. Because of the length of Volume II, it has been split into two parts for publication purposes. Part 1 contains Appendices A-Q; Part 2 contains Appendices R-MM. Separate abstracts have been prepared for each appendix for inclusion in the Energy Data Base

Subseabed disposal program annual report, January-December 1980. Volume II. Appendices (principal investigator progress reports). Part 1

Energy Technology Data Exchange (ETDEWEB)

Hinga, K.R. (ed.)

1981-07-01

Volume II of the sixth annual report describing the progress and evaluating the status of the Subseabed Disposal Program contains the appendices referred to in Volume I, Summary and Status. Because of the length of Volume II, it has been split into two parts for publication purposes. Part 1 contains Appendices A-Q; Part 2 contains Appendices R-MM. Separate abstracts have been prepared for each appendix for inclusion in the Energy Data Base.

Starting a hospital-based home health agency: Part II--Key success factors.

Science.gov (United States)

Montgomery, P

1993-09-01

In Part II of a three-part series, the financial, technological and legislative issues of a hospital-based home health-agency are discussed. Beginning a home healthcare service requires intensive research to answer key environmental and operational questions--need, competition, financial projections, initial start-up costs and the impact of delayed depreciation. Assessments involving technology, staffing, legislative and regulatory issues can help project service volume, productivity and cost-control.

Association Between National Board Dental Examination Part II Scores and Comprehensive Examinations at Harvard School of Dental Medicine.

Science.gov (United States)

Lee, Min Kyeong; Allareddy, Veerasathpurush; Howell, T Howard; Karimbux, Nadeem Y

2011-01-01

Harvard School of Dental Medicine (HSDM) uses a hybrid problem-based approach to teaching in the predoctoral program. The objective structured clinical examination (OSCE) is a formative examination designed to assess the performance of students in the problem-based learning (PBL) curriculum. At HSDM three comprehensive examinations with OSCE components are administered during the third and fourth years of clinical training. The National Board Dental Examination (NBDE) Part II is taken in the final year of the predoctoral program. This study examines the association between the NBDE Part II and the comprehensive exams held at HSDM. Predoctoral students from the HSDM classes of 2005 and 2006 were included in this study. The outcome variable of interest was the scores obtained by students in the NBDE Part II, and the main independent variable of interest was the performance of students in the comprehensive exams (honors, pass, make-up exam to pass). The Mann-Whitney U-test was used to examine the association between the grades obtained in the each of the three comprehensive exams and the NBDE Part II scores. Multivariable linear regression analysis was also used to examine the association between the NBDE Part II scores and the comprehensive exam grades. The effect of potential confounding factors including age, sex, and race/ethnicity was adjusted. The results suggest that students who performed well in the comprehensive exams performed better on the NBDE Part II, even after adjusting for confounding factors. Future studies will examine the long-term impact of PBL on postdoctoral plans and career choices.

Intelligent control of HVAC systems. Part II: perceptron performance analysis

Directory of Open Access Journals (Sweden)

Ioan URSU

2013-09-01

Full Text Available This is the second part of a paper on intelligent type control of Heating, Ventilating, and Air-Conditioning (HVAC systems. The whole study proposes a unified approach in the design of intelligent control for such systems, to ensure high energy efficiency and air quality improving. In the first part of the study it is considered as benchmark system a single thermal space HVAC system, for which it is assigned a mathematical model of the controlled system and a mathematical model(algorithm of intelligent control synthesis. The conception of the intelligent control is of switching type, between a simple neural network, a perceptron, which aims to decrease (optimize a cost index,and a fuzzy logic component, having supervisory antisaturating role for neuro-control. Based on numerical simulations, this Part II focuses on the analysis of system operation in the presence only ofthe neural control component. Working of the entire neuro-fuzzy system will be reported in a third part of the study.

International Working Group on Fast Reactors Thirteenth Annual Meeting. Summary Report. Part II

International Nuclear Information System (INIS)

1980-10-01

The Thirteenth Annual Meeting of the IAEA International Working Group on Fast Reactors was held at the IAEA Headquarters, Vienna, Austria from 9 to 11 April 1980. The Summary Report (Part I) contains the Minutes of the Meeting. The Summary Report (Part II) contains the papers which review the national programme in the field of LMFBRs and other presentations at the Meeting. The Summary Report (Part III) contains the discussions on the review of the national programmes

Delivery systems for biopharmaceuticals. Part II: Liposomes, Micelles, Microemulsions and Dendrimers.

Science.gov (United States)

Silva, Ana C; Lopes, Carla M; Lobo, José M S; Amaral, Maria H

2015-01-01

Biopharmaceuticals are a generation of drugs that include peptides, proteins, nucleic acids and cell products. According to their particular molecular characteristics (e.g. high molecular size, susceptibility to enzymatic activity), these products present some limitations for administration and usually parenteral routes are the only option. To avoid these limitations, different colloidal carriers (e.g. liposomes, micelles, microemulsions and dendrimers) have been proposed to improve biopharmaceuticals delivery. Liposomes are promising drug delivery systems, despite some limitations have been reported (e.g. in vivo failure, poor long-term stability and low transfection efficiency), and only a limited number of formulations have reached the market. Micelles and microemulsions require more studies to exclude some of the observed drawbacks and guarantee their potential for use in clinic. According to their peculiar structures, dendrimers have been showing good results for nucleic acids delivery and a great development of these systems during next years is expected. This is the Part II of two review articles, which provides the state of the art of biopharmaceuticals delivery systems. Part II deals with liposomes, micelles, microemulsions and dendrimers.

Signs of revision in Don Quixote, Part II

Directory of Open Access Journals (Sweden)

Gonzalo Pontón

2016-11-01

Full Text Available This article provides new evidences in favour of the hypothesis that Cervantes, after finishing Don Quixote, Part II, partially revised the original, introducing some significant changes and additions, mainly in the last chapters. The analysis of some narrative inconsistencies, that cannot be interpreted as mere mistakes but as significant textual traces, reveals a process of re-elaboration –a process that affects at least four sections of the novel. Most of the evidence gathered here suggests that this revision is closely linked to Avellaneda’s continuation, in the sense that Cervantes tried to challenge the apocriphal Quixote making last-time interventions in his own text.

Nursing as concrete philosophy, Part II: Engaging with reality.

Science.gov (United States)

Theodoridis, Kyriakos

2018-04-01

This is the second paper of an essay in two parts. The first paper (Part I) is a critical discussion of Mark Risjord's conception of nursing knowledge where I argued against the conception of nursing knowledge as a kind of nursing science. The aim of the present paper (Part II) is to explicate and substantiate the thesis of nursing as a kind of concrete philosophy. My strategy is to elaborate upon certain themes from Wittgenstein's Tractatus in order to canvass a general scheme of philosophy based on a distinction between reality and the world. This distinction will be employed in the appropriation of certain significant features of nursing and nursing knowledge. By elaborating on the contrast between the abstract and the concrete, I will suggest that nursing may be seen as a kind of concrete philosophy, being primarily concerned with reality (and secondarily with the world). This thesis, I will argue, implies that philosophy is the kind of theory that is essential to nursing (which is not so much a theory than a certain kind of activity). © 2017 John Wiley & Sons Ltd.

The "Pseudocommando" mass murderer: part II, the language of revenge.

Science.gov (United States)

Knoll, James L

2010-01-01

In Part I of this article, research on pseudocommandos was reviewed, and the important role that revenge fantasies play in motivating such persons to commit mass murder-suicide was discussed. Before carrying out their mass shootings, pseudocommandos may communicate some final message to the public or news media. These communications are rich sources of data about their motives and psychopathology. In Part II of this article, forensic psycholinguistic analysis is applied to clarify the primary motivations, detect the presence of mental illness, and discern important individual differences in the final communications of two recent pseudocommandos: Seung-Hui Cho (Virginia Tech) and Jiverly Wong (Binghamton, NY). Although both men committed offenses that qualify them as pseudocommandos, their final communications reveal striking differences in their psychopathology.

CE and nanomaterials - Part II: Nanomaterials in CE.

Science.gov (United States)

Adam, Vojtech; Vaculovicova, Marketa

2017-10-01

The scope of this two-part review is to summarize publications dealing with CE and nanomaterials together. This topic can be viewed from two broad perspectives, and this article is trying to highlight these two approaches: (i) CE of nanomaterials, and (ii) nanomaterials in CE. The second part aims at summarization of publications dealing with application of nanomaterials for enhancement of CE performance either in terms of increasing the separation resolution or for improvement of the detection. To increase the resolution, nanomaterials are employed as either surface modification of the capillary wall forming open tubular column or as additives to the separation electrolyte resulting in a pseudostationary phase. Moreover, nanomaterials have proven to be very beneficial for increasing also the sensitivity of detection employed in CE or even they enable the detection (e.g., fluorescent tags of nonfluorescent molecules). © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

40 CFR Appendix III to Part 266 - Tier II Emission Rate Screening Limits for Free Chlorine and Hydrogen Chloride

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Tier II Emission Rate Screening Limits for Free Chlorine and Hydrogen Chloride III Appendix III to Part 266 Protection of Environment... to Part 266—Tier II Emission Rate Screening Limits for Free Chlorine and Hydrogen Chloride Terrain...

The year 2013 in the European Heart Journal--Cardiovascular Imaging: Part II.

Science.gov (United States)

Plein, Sven; Edvardsen, Thor; Pierard, Luc A; Saraste, Antti; Knuuti, Juhani; Maurer, Gerald; Lancellotti, Patrizio

2014-08-01

The new multi-modality cardiovascular imaging journal, European Heart Journal - Cardiovascular Imaging, was created in 2012. Here we summarize the most important studies from the journal's second year in two articles. Part I of the review has summarized studies in myocardial function, myocardial ischaemia, and emerging techniques in cardiovascular imaging. Part II is focussed on valvular heart diseases, heart failure, cardiomyopathies, and congenital heart diseases. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2014. For permissions please email: journals.permissions@oup.com.

Subseabed disposal program annual report, January-December 1979. Volume II. Appendices (principal investigator progress reports). Part 1 of 2

International Nuclear Information System (INIS)

Talbert, D.M.

1981-04-01

Volume II of the sixth annual report describing the progress and evaluating the status of the Subseabed Disposal Program contains the appendices referred to in Volume I, Summary and Status. Because of the length of Volume II, it has been split into two parts for publication purposes. Part 1 contains Appendices A-O; Part 2 contains Appendices P-FF. Separate abstracts have been prepared of each Appendix for inclusion in the Energy Data Base

On the Processing of Spalling Experiments. Part II: Identification of Concrete Fracture Energy in Dynamic Tension

Science.gov (United States)

Lukić, Bratislav B.; Saletti, Dominique; Forquin, Pascal

2017-12-01

This paper presents a second part of the study aimed at investigating the fracture behavior of concrete under high strain rate tensile loading. The experimental method together with the identified stress-strain response of three tests conducted on ordinary concrete have been presented in the paper entitled Part I (Forquin and Lukić in Journal of Dynamic Behavior of Materials, 2017. https://doi.org/10.1007/s40870-017-0135-1). In the present paper, Part II, the investigation is extended towards directly determining the specific fracture energy of each observed fracture zone by visualizing the dynamic cracking process with a temporal resolution of 1 µs. Having access to temporal displacement fields of the sample surface, it is possible to identify the fracture opening displacement (FOD) and the fracture opening velocity of any principle (open) and secondary (closed) fracture at each measurement instance, that may or may not lead to complete physical failure of the sample. Finally, the local Stress-FOD curves were obtained for each observed fracture zone, opposed to previous works where indirect measurements were used. The obtained results indicated a much lower specific fracture energy compared to the results often found in the literature. Furthermore, numerical simulations were performed with a damage law to evaluate the validity of the proposed experimental data processing and compare it to the most often used one in the previous works. The results showed that the present method can reliably predict the specific fracture energy needed to open one macro-fracture and suggested that indirect measurement techniques can lead to an overestimate of specific fracture energy due to the stringent assumption of linear elasticity up-to the peak and the inability of having access to the real post-peak change of axial stress.

A Green Bank Telescope Survey of Large Galactic H II Regions

Science.gov (United States)

Anderson, L. D.; Armentrout, W. P.; Luisi, Matteo; Bania, T. M.; Balser, Dana S.; Wenger, Trey V.

2018-02-01

As part of our ongoing H II Region Discovery Survey (HRDS), we report the Green Bank Telescope detection of 148 new angularly large Galactic H II regions in radio recombination line (RRL) emission. Our targets are located at a declination of δ > -45^\\circ , which corresponds to 266^\\circ > {\\ell }> -20^\\circ at b=0^\\circ . All sources were selected from the Wide-field Infrared Survey Explorer Catalog of Galactic H II Regions, and have infrared angular diameters ≥slant 260\\prime\\prime . The Galactic distribution of these “large” H II regions is similar to that of the previously known sample of Galactic H II regions. The large H II region RRL line width and peak line intensity distributions are skewed toward lower values, compared with that of previous HRDS surveys. We discover seven sources with extremely narrow RRLs 100 {pc}, making them some of the physically largest known H II regions in the Galaxy. This survey completes the HRDS H II region census in the Northern sky, where we have discovered 887 H II regions and more than doubled the size of the previously known census of Galactic H II regions.

Bloqueio do nervo supraescapular: procedimento importante na prática clínica. Parte II Suprascapular nerve block: important procedure in clinical practice. Part II

Directory of Open Access Journals (Sweden)

Marcos Rassi Fernandes

2012-08-01

Full Text Available O bloqueio do nervo supraescapular é um método de tratamento reprodutível, confiável e extremamente efetivo no controle da dor no ombro. Esse método tem sido amplamente utilizado por profissionais na prática clínica, como reumatologistas, ortopedistas, neurologistas e especialistas em dor, na terapêutica de enfermidades crônicas, como lesão irreparável do manguito rotador, artrite reumatoide, sequelas de AVC e capsulite adesiva, o que justifica a presente revisão (Parte II. O objetivo deste estudo foi descrever as técnicas do procedimento e suas complicações descritas na literatura, já que a primeira parte reportou as indicações clínicas, drogas e volumes utilizados em aplicação única ou múltipla. Apresentamse, detalhadamente, os acessos para a realização do procedimento tanto direto como indireto, anterior e posterior, lateral e medial, e superior e inferior. Diversas são as opções para se realizar o bloqueio do nervo supraescapular. Apesar de raras, as complicações podem ocorrer. Quando bem indicado, este método deve ser considerado.The suprascapular nerve block is a reproducible, reliable, and extremely effective treatment method in shoulder pain control. This method has been widely used by professionals in clinical practice such as rheumatologists, orthopedists, neurologists, and pain specialists in the treatment of chronic diseases such as irreparable rotator cuff injury, rheumatoid arthritis, stroke sequelae, and adhesive capsulitis, which justifies the present review (Part II. The objective of this study was to describe the techniques and complications of the procedure described in the literature, as the first part reported the clinical indications, drugs, and volumes used in single or multiple procedures. We present in details the accesses used in the procedure: direct and indirect, anterior and posterior, lateral and medial, upper and lower. There are several options to perform suprascapular nerve block

Three Mile Island: a report to the commissioners and to the public. Volume II, Part 3

International Nuclear Information System (INIS)

1979-01-01

This is the third and final part of the second volume of a study of the Three Mile Island accident. Part 3 of Volume II contains descriptions and assessments of responses to the accident by the utility and by the NRC and other government agencies

Numerical Simulation of Projectile Impact on Mild Steel Armour Platesusing LS-DYNA, Part II: Parametric Studies

OpenAIRE

M. Raguraman; A. Deb; N. K. Gupta; D. K. Kharat

2008-01-01

In Part I of the current two-part series, a comprehensive simulation-based study of impact of jacketed projectiles on mild steel armour plates has been presented. Using the modelling procedures developed in Part I, a number of parametric studies have been carried out for the same mild steel plates considered in Part I and reported here in Part II. The current investigation includes determination of ballistic limits of a given target plate for different projectile diameters and impact velociti...

PIC Simulations in Low Energy Part of PIP-II Proton Linac

Energy Technology Data Exchange (ETDEWEB)

Romanov, Gennady

2014-07-01

The front end of PIP-II linac is composed of a 30 keV ion source, low energy beam transport line (LEBT), 2.1 MeV radio frequency quadrupole (RFQ), and medium energy beam transport line (MEBT). This configuration is currently being assembled at Fermilab to support a complete systems test. The front end represents the primary technical risk with PIP-II, and so this step will validate the concept and demonstrate that the hardware can meet the specified requirements. SC accelerating cavities right after MEBT require high quality and well defined beam after RFQ to avoid excessive particle losses. In this paper we will present recent progress of beam dynamic study, using CST PIC simulation code, to investigate partial neutralization effect in LEBT, halo and tail formation in RFQ, total emittance growth and beam losses along low energy part of the linac.

Contamination smoke: a simulation of heavy metal containing aerosols from fires in plutonium glove boxes: part II

International Nuclear Information System (INIS)

Buijs, K.; Chavane de Dalmassy, B.; Baumgaertner, E.

1992-01-01

The study of the dispersion of plutonium bearing aerosols during glove box fires on a laboratory scale has been, in part I of this work, focussed on fires of polymethylmethacrylate (PMMA - the major glove box construction material) whose surfaces were contaminated with cerium-europium oxide powder as a substitute for plutonium-uranium oxide. The present part II completes the study with comparative fire experiments involving contaminated samples of various glove box materials burning in or exposed to the flames of the standardized 0.6 MW fire source previously developed. Beyond spreading of the Ce-Eu-oxide powder as mentioned above, the other important surface contamination process is used, i.e. deposition and subsequent drying of droplets from acid cerium-europium solutions. It is shown that, among the tested materials, and with the exception of synthetic glove rubber, burning PMMA spreads the most radioactive contamination. On the other hand, this potential risk is much lower for fires involving materials contaminated from solution deposition than from powder or pellets. Attempts to measure the airborne contaminant particle sizes did not yield conclusive results. They suggest, however, that contamination from solutions leads to smaller heavy-metal containing aerosol particles than contamination with powder

A thermoelectric power generating heat exchanger: Part II – Numerical modeling and optimization

DEFF Research Database (Denmark)

Sarhadi, Ali; Bjørk, Rasmus; Lindeburg, N.

2016-01-01

In Part I of this study, the performance of an experimental integrated thermoelectric generator (TEG)-heat exchanger was presented. In the current study, Part II, the obtained experimental results are compared with those predicted by a finite element (FE) model. In the simulation of the integrated...... TEG-heat exchanger, the thermal contact resistance between the TEG and the heat exchanger is modeled assuming either an ideal thermal contact or using a combined Cooper–Mikic–Yovanovich (CMY) and parallel plate gap formulation, which takes into account the contact pressure, roughness and hardness...

Understanding Medicines: Conceptual Analysis of Nurses' Needs for Knowledge and Understanding of Pharmacology (Part I). Understanding Medicines: Extending Pharmacology Education for Dependent and Independent Prescribing (Part II).

Science.gov (United States)

Leathard, Helen L.

2001-01-01

Part I reviews what nurses need to know about the administration and prescription of medicines. Part II addresses drug classifications, actions and effects, and interactions. Also discussed are the challenges pharmacological issues pose for nursing education. (SK)

Uncertainty estimation with a small number of measurements, part II: a redefinition of uncertainty and an estimator method

Science.gov (United States)

Huang, Hening

2018-01-01

This paper is the second (Part II) in a series of two papers (Part I and Part II). Part I has quantitatively discussed the fundamental limitations of the t-interval method for uncertainty estimation with a small number of measurements. This paper (Part II) reveals that the t-interval is an ‘exact’ answer to a wrong question; it is actually misused in uncertainty estimation. This paper proposes a redefinition of uncertainty, based on the classical theory of errors and the theory of point estimation, and a modification of the conventional approach to estimating measurement uncertainty. It also presents an asymptotic procedure for estimating the z-interval. The proposed modification is to replace the t-based uncertainty with an uncertainty estimator (mean- or median-unbiased). The uncertainty estimator method is an approximate answer to the right question to uncertainty estimation. The modified approach provides realistic estimates of uncertainty, regardless of whether the population standard deviation is known or unknown, or if the sample size is small or large. As an application example of the modified approach, this paper presents a resolution to the Du-Yang paradox (i.e. Paradox 2), one of the three paradoxes caused by the misuse of the t-interval in uncertainty estimation.

Bayesian inference for psychology. Part II: Example applications with JASP.

Science.gov (United States)

Wagenmakers, Eric-Jan; Love, Jonathon; Marsman, Maarten; Jamil, Tahira; Ly, Alexander; Verhagen, Josine; Selker, Ravi; Gronau, Quentin F; Dropmann, Damian; Boutin, Bruno; Meerhoff, Frans; Knight, Patrick; Raj, Akash; van Kesteren, Erik-Jan; van Doorn, Johnny; Šmíra, Martin; Epskamp, Sacha; Etz, Alexander; Matzke, Dora; de Jong, Tim; van den Bergh, Don; Sarafoglou, Alexandra; Steingroever, Helen; Derks, Koen; Rouder, Jeffrey N; Morey, Richard D

2018-02-01

Bayesian hypothesis testing presents an attractive alternative to p value hypothesis testing. Part I of this series outlined several advantages of Bayesian hypothesis testing, including the ability to quantify evidence and the ability to monitor and update this evidence as data come in, without the need to know the intention with which the data were collected. Despite these and other practical advantages, Bayesian hypothesis tests are still reported relatively rarely. An important impediment to the widespread adoption of Bayesian tests is arguably the lack of user-friendly software for the run-of-the-mill statistical problems that confront psychologists for the analysis of almost every experiment: the t-test, ANOVA, correlation, regression, and contingency tables. In Part II of this series we introduce JASP ( http://www.jasp-stats.org ), an open-source, cross-platform, user-friendly graphical software package that allows users to carry out Bayesian hypothesis tests for standard statistical problems. JASP is based in part on the Bayesian analyses implemented in Morey and Rouder's BayesFactor package for R. Armed with JASP, the practical advantages of Bayesian hypothesis testing are only a mouse click away.

Scope Oriented Thermoeconomic analysis of energy systems. Part II: Formation Structure of Optimality for robust design

International Nuclear Information System (INIS)

Piacentino, Antonio; Cardona, Ennio

2010-01-01

This paper represents the Part II of a paper in two parts. In Part I the fundamentals of Scope Oriented Thermoeconomics have been introduced, showing a scarce potential for the cost accounting of existing plants; in this Part II the same concepts are applied to the optimization of a small set of design variables for a vapour compression chiller. The method overcomes the limit of most conventional optimization techniques, which are usually based on hermetic algorithms not enabling the energy analyst to recognize all the margins for improvement. The Scope Oriented Thermoeconomic optimization allows us to disassemble the optimization process, thus recognizing the Formation Structure of Optimality, i.e. the specific influence of any thermodynamic and economic parameter in the path toward the optimal design. Finally, the potential applications of such an in-depth understanding of the inner driving forces of the optimization are discussed in the paper, with a particular focus on the sensitivity analysis to the variation of energy and capital costs and on the actual operation-oriented design.

Structure Learning and Statistical Estimation in Distribution Networks - Part II

Energy Technology Data Exchange (ETDEWEB)

Deka, Deepjyoti [Univ. of Texas, Austin, TX (United States); Backhaus, Scott N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Chertkov, Michael [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2015-02-13

Limited placement of real-time monitoring devices in the distribution grid, recent trends notwithstanding, has prevented the easy implementation of demand-response and other smart grid applications. Part I of this paper discusses the problem of learning the operational structure of the grid from nodal voltage measurements. In this work (Part II), the learning of the operational radial structure is coupled with the problem of estimating nodal consumption statistics and inferring the line parameters in the grid. Based on a Linear-Coupled(LC) approximation of AC power flows equations, polynomial time algorithms are designed to identify the structure and estimate nodal load characteristics and/or line parameters in the grid using the available nodal voltage measurements. Then the structure learning algorithm is extended to cases with missing data, where available observations are limited to a fraction of the grid nodes. The efficacy of the presented algorithms are demonstrated through simulations on several distribution test cases.

Emerging Forms of the Part II of Jonathan Swift's Novel “Gulliver’s Travels”

Directory of Open Access Journals (Sweden)

Svitlana Tikhonenko

2017-11-01

Full Text Available The article is devoted to the study of grotesque forms in Jonathan Swift's novel "Gulliver’s Travels" based on the text of part II of the novel "A Voyage to Brobdingnag". On the basis of the selected actual material, displays of the grotesque elements in the semantic field of the work’s text are traced. The grotesque world of the novel is the author's model of mankind, in which J. Swift presents his view not only on the state of the modern system of England, but also on the nature of man in general, reveals the peculiarities of the psychology of human nature, especially human socialization. In part II, the author continues to develop a complex and contradictory picture of human existence in front of the reader, the world of giants appears as an ambivalent system in which the features of an ideal society and ideal ruler, in author’s opinion, with the ugly face of man and society, are marvelously combined.

Numerical simulation of projectile impact on mild steel armour plates using LS-DYNA, Part II: Parametric studies

OpenAIRE

Raguraman, M; Deb, A; Gupta, NK; Kharat, DK

2008-01-01

In Part I of the current two-part series, a comprehensive simulation-based study of impact of Jacketed projectiles on mild steel armour plates has been presented. Using the modelling procedures developed in Part I, a number of parametric studies have been carried out for the same mild steel plates considered in Part I and reported here in Part II. The current investigation includes determination of ballistic limits of a given target plate for different projectile diameters and impact velociti...

Technical Information on the Carbonation of the EBR-II Reactor, Summary Report Part 1: Laboratory Experiments and Application to EBR-II Secondary Sodium System

Energy Technology Data Exchange (ETDEWEB)

Steven R. Sherman

2005-04-01

Residual sodium is defined as sodium metal that remains behind in pipes, vessels, and tanks after the bulk sodium metal has been melted and drained from such components. The residual sodium has the same chemical properties as bulk sodium, and differs from bulk sodium only in the thickness of the sodium deposit. Typically, sodium is considered residual when the thickness of the deposit is less than 5-6 cm. This residual sodium must be removed or deactivated when a pipe, vessel, system, or entire reactor is permanently taken out of service, in order to make the component or system safer and/or to comply with decommissioning regulations. As an alternative to the established residual sodium deactivation techniques (steam-and-nitrogen, wet vapor nitrogen, etc.), a technique involving the use of moisture and carbon dioxide has been developed. With this technique, sodium metal is converted into sodium bicarbonate by reacting it with humid carbon dioxide. Hydrogen is emitted as a by-product. This technique was first developed in the laboratory by exposing sodium samples to humidified carbon dioxide under controlled conditions, and then demonstrated on a larger scale by treating residual sodium within the Experimental Breeder Reactor II (EBR-II) secondary cooling system, followed by the primary cooling system, respectively. The EBR-II facility is located at the Idaho National Laboratory (INL) in southeastern Idaho, U.S.A. This report is Part 1 of a two-part report. It is divided into three sections. The first section describes the chemistry of carbon dioxide-water-sodium reactions. The second section covers the laboratory experiments that were conducted in order to develop the residual sodium deactivation process. The third section discusses the application of the deactivation process to the treatment of residual sodium within the EBR-II secondary sodium cooling system. Part 2 of the report, under separate cover, describes the application of the technique to residual sodium

HERBICIDAS INIBIDORES DO FOTOSSISTEMA II – PARTE II / PHOTOSYSTEM II INHIBITOR HERBICIDES - PART

Directory of Open Access Journals (Sweden)

ILCA P. DE F. E SILVA

2013-11-01

Full Text Available Os herbicidas inibidores do fotossistema II (PSII ligam-se ao sítio da QB localizado na proteína D1 o qual se localiza na membrana dos tilacóides dos cloroplastos, causando, o bloqueia do transporte de elétrons da QA para QB, tendo como consequência, a peroxidação dos lipídios. Os principais fatores que afetam a evolução da resistência de plantas daninhas aos herbicidas têm sido agrupados em: genéticos, bioecológicos e agronômicos. A resistência de plantas daninhas a herbicidas é definida como a habilidade de uma planta sobreviver e reproduzir, após exposição a uma dose de herbicida normalmente letal para um biótipo normal da planta. A seletividade de um herbicida está relacionada à capacidade de eliminar plantas daninhas sem interferir na qualidade da planta de interesse econômico.

Polycystic ovary syndrome: a review for dermatologists: Part II. Treatment.

Science.gov (United States)

Buzney, Elizabeth; Sheu, Johanna; Buzney, Catherine; Reynolds, Rachel V

2014-11-01

Dermatologists are in a key position to treat the manifestations of polycystic ovary syndrome (PCOS). The management of PCOS should be tailored to each woman's specific goals, reproductive interests, and particular constellation of symptoms. Therefore, a multidisciplinary approach is recommended. In part II of this continuing medical education article, we present the available safety and efficacy data regarding treatments for women with acne, hirsutism, and androgenetic alopecia. Therapies discussed include lifestyle modification, topical therapies, combined oral contraceptives, antiandrogen agents, and insulin-sensitizing drugs. Treatment recommendations are made based on the current available evidence. Copyright © 2014 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

Recovery in soccer : part ii-recovery strategies.

Science.gov (United States)

Nédélec, Mathieu; McCall, Alan; Carling, Chris; Legall, Franck; Berthoin, Serge; Dupont, Gregory

2013-01-01

In the formerly published part I of this two-part review, we examined fatigue after soccer matchplay and recovery kinetics of physical performance, and cognitive, subjective and biological markers. To reduce the magnitude of fatigue and to accelerate the time to fully recover after completion, several recovery strategies are now used in professional soccer teams. During congested fixture schedules, recovery strategies are highly required to alleviate post-match fatigue, and then to regain performance faster and reduce the risk of injury. Fatigue following competition is multifactorial and mainly related to dehydration, glycogen depletion, muscle damage and mental fatigue. Recovery strategies should consequently be targeted against the major causes of fatigue. Strategies reviewed in part II of this article were nutritional intake, cold water immersion, sleeping, active recovery, stretching, compression garments, massage and electrical stimulation. Some strategies such as hydration, diet and sleep are effective in their ability to counteract the fatigue mechanisms. Providing milk drinks to players at the end of competition and a meal containing high-glycaemic index carbohydrate and protein within the hour following the match are effective in replenishing substrate stores and optimizing muscle-damage repair. Sleep is an essential part of recovery management. Sleep disturbance after a match is common and can negatively impact on the recovery process. Cold water immersion is effective during acute periods of match congestion in order to regain performance levels faster and repress the acute inflammatory process. Scientific evidence for other strategies reviewed in their ability to accelerate the return to the initial level of performance is still lacking. These include active recovery, stretching, compression garments, massage and electrical stimulation. While this does not mean that these strategies do not aid the recovery process, the protocols implemented up until

Ocean Thermal Energy Converstion (OTEC) test facilities study program. Final report. Volume II. Part B

Energy Technology Data Exchange (ETDEWEB)

None

1977-01-17

Results are presented of an 8-month study to develop alternative non-site-specific OTEC facilities/platform requirements for an integrated OTEC test program which may include land and floating test facilities. Volume II--Appendixes is bound in three parts (A, B, and C) which together comprise a compendium of the most significant detailed data developed during the study. Part B provides an annotated test list and describes component tests and system tests.

Not-for-profit versus for-profit health care providers--Part II: Comparing and contrasting their records.

Science.gov (United States)

Rotarius, Timothy; Trujillo, Antonio J; Liberman, Aaron; Ramirez, Bernardo

2006-01-01

The debate over which health care providers are most capably meeting their responsibilities in serving the public's interest continues unabated, and the comparisons of not-for-profit (NFP) versus for-profit (FP) hospitals remain at the epicenter of the discussion. From the perspective of available factual information, which of the two sides to this debate is correct? This article is part II of a 2-part series on comparing and contrasting the performance records of NFP health care providers with their FP counterparts. Although it is demonstrated that both NFP and FP providers perform virtuous and selfless feats on behalf of America's public, it is also shown that both camps have been accused of being involved in potentially willful clinical and administrative missteps. Part I provided the background information (eg, legal differences, perspectives on social responsibility, and types of questionable and fraudulent behavior) required to adequately understand the scope of the comparison issue. Part II offers actual comparisons of the 2 organizational structures using several disparate factors such as specific organizational behaviors, approach to the health care priorities of cost and quality, and business-focused goals of profits, efficiency, and community benefit.

Transport properties of gaseous ions over a wide energy range. Part III

International Nuclear Information System (INIS)

Ellis, H.W.; Thackston, M.G.; McDaniel, E.W.; Mason, E.A.

1984-01-01

This paper updates and extends in scope our two previous papers entitled ''Transport Properties of Gaseous Ions over a Wide Energy Range.'' The references to the earlier publications (referred to as ''Part I'' and ''Part II'') are I, H. W. Ellis, R. Y. Pai, E. W. McDonald, E. A. Mason, and L. A. Viehland, ATOMIC DATA AND NUCLEAR DATA TABLES 17, 177--210 (19876); and II, H. W. Ellis, E. W. McDaniel, D. L. Albritton, L. A. Veihland, S. L. Lin, and E. A. Mason, ATOMIC DATA AND NUCLEAR DATA TABLES 22, 179--217 (1978). Parts I and II contained compilations of experimental data on ionic mobilities and diffusion coefficients (both longitudinal and transverse) for ions in neutral gase (almost exclusively at room temperature) in an externally applied electric field

Eleventh annual meeting, Bologna, Italy, 17-20 April 1978. Summary report. Part II

Energy Technology Data Exchange (ETDEWEB)

NONE

1978-07-01

The Summary Report - Part II of the Eleventh Annual Meeting of the IAEA International Working Group on Fast Reactors - includes reports on development of fast reactors in France from 1977 to 1978; review of the activities related to fast reactors in Germany; status of fast breeder reactors development in Belgium and Netherlands; status of activities related to fast reactors in USSR, Japan USA, UK and Italy.

Eleventh annual meeting, Bologna, Italy, 17-20 April 1978. Summary report. Part II

International Nuclear Information System (INIS)

1978-07-01

The Summary Report - Part II of the Eleventh Annual Meeting of the IAEA International Working Group on Fast Reactors - includes reports on development of fast reactors in France from 1977 to 1978; review of the activities related to fast reactors in Germany; status of fast breeder reactors development in Belgium and Netherlands; status of activities related to fast reactors in USSR, Japan USA, UK and Italy

A legacy of struggle: the OSHA ergonomics standard and beyond, Part II.

Science.gov (United States)

Delp, Linda; Mojtahedi, Zahra; Sheikh, Hina; Lemus, Jackie

2014-11-01

The OSHA ergonomics standard issued in 2000 was repealed within four months through a Congressional resolution that limits future ergonomics rulemaking. This section continues the conversation initiated in Part I, documenting a legacy of struggle for an ergonomics standard through the voices of eight labor, academic, and government key informants. Part I summarized important components of the standard; described the convergence of labor activism, research, and government action that laid the foundation for a standard; and highlighted the debates that characterized the rulemaking process. Part II explores the anti-regulatory political landscape of the 1990s, as well as the key opponents, power dynamics, and legal maneuvers that led to repeal of the standard. This section also describes the impact of the ergonomics struggle beyond the standard itself and ends with a discussion of creative state-level policy initiatives and coalition approaches to prevent work-related musculoskeletal disorders (WMSDs) in today's sociopolitical context.

Combustion chemistry and flame structure of furan group biofuels using molecular-beam mass spectrometry and gas chromatography - Part II: 2-Methylfuran.

Science.gov (United States)

Tran, Luc-Sy; Togbé, Casimir; Liu, Dong; Felsmann, Daniel; Oßwald, Patrick; Glaude, Pierre-Alexandre; Fournet, René; Sirjean, Baptiste; Battin-Leclerc, Frédérique; Kohse-Höinghaus, Katharina

2014-03-01

This is Part II of a series of three papers which jointly address the combustion chemistry of furan and its alkylated derivatives 2-methylfuran (MF) and 2,5-dimethylfuran (DMF) under premixed low-pressure flame conditions. Some of them are considered to be promising biofuels. With furan as a common basis studied in Part I of this series, the present paper addresses two laminar premixed low-pressure (20 and 40 mbar) flat argon-diluted (50%) flames of MF which were studied with electron-ionization molecular-beam mass spectrometry (EI-MBMS) and gas chromatography (GC) for equivalence ratios φ=1.0 and 1.7, identical conditions to those for the previously reported furan flames. Mole fractions of reactants, products as well as stable and reactive intermediates were measured as a function of the distance above the burner. Kinetic modeling was performed using a comprehensive reaction mechanism for all three fuels given in Part I and described in the three parts of this series. A comparison of the experimental results and the simulation shows reasonable agreement, as also seen for the furan flames in Part I before. This set of experiments is thus considered to be a valuable additional basis for the validation of the model. The main reaction pathways of MF consumption have been derived from reaction flow analyses, and differences to furan combustion chemistry under the same conditions are discussed.

Title II, Part A: Don't Scrap It, Don't Dilute It, Fix It

Science.gov (United States)

Coggshall, Jane G.

2015-01-01

The Issue: Washington is taking a close look at Title II, Part A (Title IIA) of the Elementary and Secondary Education Act (ESEA) as Congress debates reauthorization. The program sends roughly $2.5 billion a year to all states and nearly all districts to "(1) increase student academic achievement through strategies such as improving teacher…

Instructional Climates in Preschool Children Who Are At-Risk. Part II: Perceived Physical Competence

Science.gov (United States)

Robinson, Leah E.; Rudisill, Mary E.; Goodway, Jacqueline D.

2009-01-01

In Part II of this study, we examined the effect of two 9-week instructional climates (low-autonomy [LA] and mastery motivational climate [MMC]) on perceived physical competence (PPC) in preschoolers (N = 117). Participants were randomly assigned to an LA, MMC, or comparison group. PPC was assessed by a pretest, posttest, and retention test with…

Optimal recombination in genetic algorithms for combinatorial optimization problems: Part II

Directory of Open Access Journals (Sweden)

Eremeev Anton V.

2014-01-01

Full Text Available This paper surveys results on complexity of the optimal recombination problem (ORP, which consists in finding the best possible offspring as a result of a recombination operator in a genetic algorithm, given two parent solutions. In Part II, we consider the computational complexity of ORPs arising in genetic algorithms for problems on permutations: the Travelling Salesman Problem, the Shortest Hamilton Path Problem and the Makespan Minimization on Single Machine and some other related problems. The analysis indicates that the corresponding ORPs are NP-hard, but solvable by faster algorithms, compared to the problems they are derived from.

The basic science of dermal fillers: past and present Part II: adverse effects.

Science.gov (United States)

Gilbert, Erin; Hui, Andrea; Meehan, Shane; Waldorf, Heidi A

2012-09-01

The ideal dermal filler should offer long-lasting aesthetic improvement with a minimal side-effect profile. It should be biocompatible and stable within the injection site, with the risk of only transient undesirable effects from injection alone. However, all dermal fillers can induce serious and potentially long-lasting adverse effects. In Part II of this paper, we review the most common adverse effects related to dermal filler use.

Biology and Mechanics of Blood Flows Part II: Mechanics and Medical Aspects

CERN Document Server

Thiriet, Marc

2008-01-01

Biology and Mechanics of Blood Flows presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. Part II of this two-volume sequence, Mechanics and Medical Aspects, refers to the extraction of input data at the macroscopic scale for modeling the cardiovascular system, and complements Part I, which focuses on nanoscopic and microscopic components and processes. This volume contains chapters on anatomy, physiology, continuum mechanics, as well as pathological changes in the vasculature walls including the heart and their treatments. Methods of numerical simulations are given and illustrated in particular by application to wall diseases. This authoritative book will appeal to any biologist, chemist, physicist, or applied mathematician interested in the functioning of the cardiovascular system.

Formulation, computation and improvement of steady state security margins in power systems. Part II: Results

International Nuclear Information System (INIS)

Echavarren, F.M.; Lobato, E.; Rouco, L.; Gomez, T.

2011-01-01

A steady state security margin for a particular operating point can be defined as the distance from this initial point to the secure operating limits of the system. Four of the most used steady state security margins are the power flow feasibility margin, the contingency feasibility margin, the load margin to voltage collapse, and the total transfer capability between system areas. This is the second part of a two part paper. Part I has proposed a novel framework of a general model able to formulate, compute and improve any steady state security margin. In Part II the performance of the general model is validated by solving a variety of practical situations in modern real power systems. Actual examples of the Spanish power system will be used for this purpose. The same computation and improvement algorithms outlined in Part I have been applied for the four security margins considered in the study, outlining the convenience of defining a general framework valid for the four of them. The general model is used here in Part II to compute and improve: (a) the power flow feasibility margin (assessing the influence of the reactive power generation limits in the Spanish power system), (b) the contingency feasibility margin (assessing the influence of transmission and generation capacity in maintaining a correct voltage profile), (c) the load margin to voltage collapse (assessing the location and quantity of loads that must be shed in order to be far away from voltage collapse) and (d) the total transfer capability (assessing the export import pattern of electric power between different areas of the Spanish system). (author)

Formulation, computation and improvement of steady state security margins in power systems. Part II: Results

Energy Technology Data Exchange (ETDEWEB)

Echavarren, F.M.; Lobato, E.; Rouco, L.; Gomez, T. [School of Engineering of Universidad Pontificia Comillas, C/Alberto Aguilera, 23, 28015 Madrid (Spain)

2011-02-15

A steady state security margin for a particular operating point can be defined as the distance from this initial point to the secure operating limits of the system. Four of the most used steady state security margins are the power flow feasibility margin, the contingency feasibility margin, the load margin to voltage collapse, and the total transfer capability between system areas. This is the second part of a two part paper. Part I has proposed a novel framework of a general model able to formulate, compute and improve any steady state security margin. In Part II the performance of the general model is validated by solving a variety of practical situations in modern real power systems. Actual examples of the Spanish power system will be used for this purpose. The same computation and improvement algorithms outlined in Part I have been applied for the four security margins considered in the study, outlining the convenience of defining a general framework valid for the four of them. The general model is used here in Part II to compute and improve: (a) the power flow feasibility margin (assessing the influence of the reactive power generation limits in the Spanish power system), (b) the contingency feasibility margin (assessing the influence of transmission and generation capacity in maintaining a correct voltage profile), (c) the load margin to voltage collapse (assessing the location and quantity of loads that must be shed in order to be far away from voltage collapse) and (d) the total transfer capability (assessing the export import pattern of electric power between different areas of the Spanish system). (author)

Exploring Water Pollution. Part II

Science.gov (United States)

Rillo, Thomas J.

1975-01-01

This is part two of a three part article related to the science activity of exploring environmental problems. Part one dealt with background information for the classroom teacher. Presented here is a suggested lesson plan on water pollution. Objectives, important concepts and instructional procedures are suggested. (EB)

Part I: $\\beta$-delayed fission, laser spectroscopy and shape-coexistence studies with astatine beams; Part II: Delineating the island of deformation in the light gold isotopes by means of laser spectroscopy

CERN Document Server

Andreyev, Andrei

2013-01-01

Part I: $\\beta$-delayed fission, laser spectroscopy and shape-coexistence studies with astatine beams; Part II: Delineating the island of deformation in the light gold isotopes by means of laser spectroscopy

Final environmental statement. Final addendum to Part II: Manufacture of floating nuclear power plants by Offshore Power Systems. DOCKET-STN--50-437

International Nuclear Information System (INIS)

1978-06-01

This Addendum to Part II of the Final Environmental Statement related to manufacture of floating nuclear power plants by Offshore Power Systems (OPS), NUREG-0056, issued September 1976, was prepared by the U.S. Nuclear Regulatory Commission (NRC), Office of Nuclear Reactor Regulation. The staff's basic evaluation is presented in NUREG-0056. The current Addendum provides further consideration of a number of topics discussed in NUREG-0056, particularly additional consideration of shore zone siting at estuarine and ocean regions. This Summary and Conclusions recapitulates and is cumulative for Part II of the FES and the current Addendum. Augmentations to the Summary and Conclusions presented in Part II of the FES and arising from the evaluations contained in this Addendum are italicized

Nuclear fuel technology - Determination of uranium in solutions, uranium hexafluoride and solids - Part 2: Iron(II) reduction/cerium(IV) oxidation titrimetric method

International Nuclear Information System (INIS)

2004-01-01

This first edition of ISO 7097-1 together with ISO 7097-2:2004 cancels and replaces ISO 7097:1983, which has been technically revised, and ISO 9989:1996. ISO 7097 consists of the following parts, under the general title Nuclear fuel technology - Determination of uranium in solutions, uranium hexafluoride and solids: Part 1: Iron(II) reduction/potassium dichromate oxidation titrimetric method; Part 2: Iron(II) reduction/cerium(IV) oxidation titrimetric method. This part 2. of ISO 7097 describes procedures for determination of uranium in solutions, uranium hexafluoride and solids. The procedures described in the two independent parts of this International Standard are similar: this part uses a titration with cerium(IV) and ISO 7097-1 uses a titration with potassium dichromate

Nuclear fuel technology - Determination of uranium in solutions, uranium hexafluoride and solids - Part 1: Iron(II) reduction/potassium dichromate oxidation titrimetric method

International Nuclear Information System (INIS)

2004-01-01

This first edition of ISO 7097-1 together with ISO 7097-2:2004 cancels and replaces ISO 7097:1983, which has been technically revised, and ISO 9989:1996. ISO 7097 consists of the following parts, under the general title Nuclear fuel technology - Determination of uranium in solutions, uranium hexafluoride and solids: Part 1: Iron(II) reduction/potassium dichromate oxidation titrimetric method; Part 2: Iron(II) reduction/cerium(IV) oxidation titrimetric method. This part 1. of ISO 7097 describes procedures for the determination of uranium in solutions, uranium hexafluoride and solids. The procedures described in the two independent parts of this International Standard are similar: this part uses a titration with potassium dichromate and ISO 7097-2 uses a titration with cerium(IV)

Current antiviral drugs and their analysis in biological materials - Part II: Antivirals against hepatitis and HIV viruses.

Science.gov (United States)

Nováková, Lucie; Pavlík, Jakub; Chrenková, Lucia; Martinec, Ondřej; Červený, Lukáš

2018-01-05

This review is a Part II of the series aiming to provide comprehensive overview of currently used antiviral drugs and to show modern approaches to their analysis. While in the Part I antivirals against herpes viruses and antivirals against respiratory viruses were addressed, this part concerns antivirals against hepatitis viruses (B and C) and human immunodeficiency virus (HIV). Many novel antivirals against hepatitis C virus (HCV) and HIV have been introduced into the clinical practice over the last decade. The recent broadening portfolio of these groups of antivirals is reflected in increasing number of developed analytical methods required to meet the needs of clinical terrain. Part II summarizes the mechanisms of action of antivirals against hepatitis B virus (HBV), HCV, and HIV, their use in clinical practice, and analytical methods for individual classes. It also provides expert opinion on state of art in the field of bioanalysis of these drugs. Analytical methods reflect novelty of these chemical structures and use by far the most current approaches, such as simple and high-throughput sample preparation and fast separation, often by means of UHPLC-MS/MS. Proper method validation based on requirements of bioanalytical guidelines is an inherent part of the developed methods. Copyright © 2017 Elsevier B.V. All rights reserved.

The simulation library of the Belle II software system

Science.gov (United States)

Kim, D. Y.; Ritter, M.; Bilka, T.; Bobrov, A.; Casarosa, G.; Chilikin, K.; Ferber, T.; Godang, R.; Jaegle, I.; Kandra, J.; Kodys, P.; Kuhr, T.; Kvasnicka, P.; Nakayama, H.; Piilonen, L.; Pulvermacher, C.; Santelj, L.; Schwenker, B.; Sibidanov, A.; Soloviev, Y.; Starič, M.; Uglov, T.

2017-10-01

SuperKEKB, the next generation B factory, has been constructed in Japan as an upgrade of KEKB. This brand new e+ e- collider is expected to deliver a very large data set for the Belle II experiment, which will be 50 times larger than the previous Belle sample. Both the triggered physics event rate and the background event rate will be increased by at least 10 times than the previous ones, and will create a challenging data taking environment for the Belle II detector. The software system of the Belle II experiment is designed to execute this ambitious plan. A full detector simulation library, which is a part of the Belle II software system, is created based on Geant4 and has been tested thoroughly. Recently the library has been upgraded with Geant4 version 10.1. The library is behaving as expected and it is utilized actively in producing Monte Carlo data sets for various studies. In this paper, we will explain the structure of the simulation library and the various interfaces to other packages including geometry and beam background simulation.

II: Through the Western Part of the City: Charlottenburg

Science.gov (United States)

Hoffmann, Dieter

Until 1920 the city we now call Berlin was a collection of independent towns and villages — among them Charlottenburg, which was one of the most important and was the proud sister of Berlin, Prussia’s and Germany’s capital, where the wealthy and innovative bourgeoisie lived. Werner von Siemens, Germany’s pioneer in the modern electrical industry, was a prime example of that elite. His castle-like villa was located not far from today’s Ernst-Reuter-Platz at Otto-Suhr-Allee 10-16, and important parts of his enterprise expanded into the “meadows outside of Charlottenburg” during the second half of the 19th century. It was no accident that the efforts to unite Berlin’s two colleges for trade and construction (both founded around 1800) led to the foundation of a modern Technical College in Charlottenburg in 1879, today’s Technical University of Berlin. Its magnificent main building (figure 1), which was opened in 1882 by the German Emperor, was an expression of the great self-confidence of this new institution of higher learning and of Charlottenburg’s bourgeoisie. Although large parts of the building were destroyed by bombs during World War II, you can still get an impression of its monumentality from what survived at number 135 Strasse des 17. Juni.

Safety analysis report for the TRUPACT-II shipping package (condensed version). Volume 1, Rev. 14

International Nuclear Information System (INIS)

1994-10-01

The condensed version of the TRUPACT-II Contact Handled Transuranic Waste Safety Analysis Report for Packaging (SARP) contains essential material required by TRUPACT-II users, plus additional contents (payload) information previously submitted to the U.S. Nuclear Regulatory Commission. All or part of the following sections, which are not required by users of the TRUPACT-II, are deleted from the condensed version: (i) structural analysis, (ii) thermal analysis, (iii) containment analysis, (iv) criticality analysis, (v) shielding analysis, and (vi) hypothetical accident test results

Safety analysis report for the TRUPACT-II shipping package (condensed version). Volume 1, Rev. 14

Energy Technology Data Exchange (ETDEWEB)

NONE

1994-10-01

The condensed version of the TRUPACT-II Contact Handled Transuranic Waste Safety Analysis Report for Packaging (SARP) contains essential material required by TRUPACT-II users, plus additional contents (payload) information previously submitted to the U.S. Nuclear Regulatory Commission. All or part of the following sections, which are not required by users of the TRUPACT-II, are deleted from the condensed version: (i) structural analysis, (ii) thermal analysis, (iii) containment analysis, (iv) criticality analysis, (v) shielding analysis, and (vi) hypothetical accident test results.

Music in the exercise domain: a review and synthesis (Part II).

Science.gov (United States)

Karageorghis, Costas I; Priest, David-Lee

2012-03-01

Since a 1997 review by Karageorghis and Terry, which highlighted the state of knowledge and methodological weaknesses, the number of studies investigating musical reactivity in relation to exercise has swelled considerably. In this two-part review paper, the development of conceptual approaches and mechanisms underlying the effects of music are explicated (Part I), followed by a critical review and synthesis of empirical work (spread over Parts I and II). Pre-task music has been shown to optimise arousal, facilitate task-relevant imagery and improve performance in simple motoric tasks. During repetitive, endurance-type activities, self-selected, motivational and stimulative music has been shown to enhance affect, reduce ratings of perceived exertion, improve energy efficiency and lead to increased work output. There is evidence to suggest that carefully selected music can promote ergogenic and psychological benefits during high-intensity exercise, although it appears to be ineffective in reducing perceptions of exertion beyond the anaerobic threshold. The effects of music appear to be at their most potent when it is used to accompany self-paced exercise or in externally valid conditions. When selected according to its motivational qualities, the positive impact of music on both psychological state and performance is magnified. Guidelines are provided for future research and exercise practitioners.

Inhibition of Hsp90 acts synergistically with topoisomerase II poisons to increase the apoptotic killing of cells due to an increase in topoisomerase II mediated DNA damage

OpenAIRE

Barker, Catherine R.; McNamara, Anne V.; Rackstraw, Stephen A.; Nelson, David E.; White, Mike R.; Watson, Alastair J. M.; Jenkins, John R.

2006-01-01

Topoisomerase II plays a crucial role during chromosome condensation and segregation in mitosis and meiosis and is a highly attractive target for chemotherapeutic agents. We have identified previously topoisomerase II and heat shock protein 90 (Hsp90) as part of a complex. In this paper we demonstrate that drug combinations targeting these two enzymes cause a synergistic increase in apoptosis. The objective of our study was to identify the mode of cell killing and the mechanism behind the inc...

Characterization of cDNA for human tripeptidyl peptidase II: The N-terminal part of the enzyme is similar to subtilisin

International Nuclear Information System (INIS)

Tomkinson, B.; Jonsson, A-K

1991-01-01

Tripeptidyl peptidase II is a high molecular weight serine exopeptidase, which has been purified from rat liver and human erythrocytes. Four clones, representing 4453 bp, or 90% of the mRNA of the human enzyme, have been isolated from two different cDNA libraries. One clone, designated A2, was obtained after screening a human B-lymphocyte cDNA library with a degenerated oligonucleotide mixture. The B-lymphocyte cDNA library, obtained from human fibroblasts, were rescreened with a 147 bp fragment from the 5' part of the A2 clone, whereby three different overlapping cDNA clones could be isolated. The deduced amino acid sequence, 1196 amino acid residues, corresponding to the longest open rading frame of the assembled nucleotide sequence, was compared to sequences of current databases. This revealed a 56% similarity between the bacterial enzyme subtilisin and the N-terminal part of tripeptidyl peptidase II. The enzyme was found to be represented by two different mRNAs of 4.2 and 5.0 kilobases, respectively, which probably result from the utilziation of two different polyadenylation sites. Futhermore, cDNA corresponding to both the N-terminal and C-terminal part of tripeptidyl peptidase II hybridized with genomic DNA from mouse, horse, calf, and hen, even under fairly high stringency conditions, indicating that tripeptidyl peptidase II is highly conserved

The equivalence myth of quantum mechanics-part II

Science.gov (United States)

Muller, F. A.

The author endeavours to show two things: first, that Schrödingers (and Eckarts) demonstration in March (September) 1926 of the equivalence of matrix mechanics, as created by Heisenberg, Born, Jordan and Dirac in 1925, and wave mechanics, as created by Schrödinger in 1926, is not foolproof; and second, that it could not have been foolproof, because at the time matrix mechanics and wave mechanics were neither mathematically nor empirically equivalent. That they were is the Equivalence Myth. In order to make the theories equivalent and to prove this, one has to leave the historical scene of 1926 and wait until 1932, when von Neumann finished his magisterial edifice. During the period 1926-1932 the original families of mathematical structures of matrix mechanics and of wave mechanics were stretched, parts were chopped off and novel structures were added. To Procrustean places we go, where we can demonstrate the mathematical, empirical and ontological equivalence of 'the final versions of' matrix mechanics and wave mechanics. The present paper claims to be a comprehensive analysis of one of the pivotal papers in the history of quantum mechanics: Schrödingers equivalence paper. Since the analysis is performed from the perspective of Suppes structural view ('semantic view') of physical theories, the present paper can be regarded not only as a morsel of the internal history of quantum mechanics, but also as a morsel of applied philosophy of science. The paper is self-contained and presupposes only basic knowledge of quantum mechanics. For reasons of length, the paper is published in two parts; Part I appeared in the previous issue of this journal. Section 1 contains, besides an introduction, also the papers five claims and a preview of the arguments supporting these claims; so Part I, Section 1 may serve as a summary of the paper for those readers who are not interested in the detailed arguments.

Combustion chemistry and flame structure of furan group biofuels using molecular-beam mass spectrometry and gas chromatography – Part II: 2-Methylfuran

Science.gov (United States)

Tran, Luc-Sy; Togbé, Casimir; Liu, Dong; Felsmann, Daniel; Oßwald, Patrick; Glaude, Pierre-Alexandre; Fournet, René; Sirjean, Baptiste; Battin-Leclerc, Frédérique; Kohse-Höinghaus, Katharina

2013-01-01

This is Part II of a series of three papers which jointly address the combustion chemistry of furan and its alkylated derivatives 2-methylfuran (MF) and 2,5-dimethylfuran (DMF) under premixed low-pressure flame conditions. Some of them are considered to be promising biofuels. With furan as a common basis studied in Part I of this series, the present paper addresses two laminar premixed low-pressure (20 and 40 mbar) flat argon-diluted (50%) flames of MF which were studied with electron-ionization molecular-beam mass spectrometry (EI-MBMS) and gas chromatography (GC) for equivalence ratios φ=1.0 and 1.7, identical conditions to those for the previously reported furan flames. Mole fractions of reactants, products as well as stable and reactive intermediates were measured as a function of the distance above the burner. Kinetic modeling was performed using a comprehensive reaction mechanism for all three fuels given in Part I and described in the three parts of this series. A comparison of the experimental results and the simulation shows reasonable agreement, as also seen for the furan flames in Part I before. This set of experiments is thus considered to be a valuable additional basis for the validation of the model. The main reaction pathways of MF consumption have been derived from reaction flow analyses, and differences to furan combustion chemistry under the same conditions are discussed. PMID:24518895

Rise, fall and resurrection of chromosome territories: a historical perspective Part II. Fall and resurrection of chromosome territories during the 1950s to 1980s. Part III. Chromosome territories and the functional nuclear architecture: experiments and m

OpenAIRE

T Cremer; C Cremer

2009-01-01

Part II of this historical review on the progress of nuclear architecture studies points out why the original hypothesis of chromosome territories from Carl Rabl and Theodor Boveri (described in part I) was abandoned during the 1950s and finally proven by compelling evidence forwarded by laser-uvmicrobeam studies and in situ hybridization experiments. Part II also includes a section on the development of advanced light microscopic techniques breaking the classical Abbe limit written for reade...

Part I: quantum fluctuations in chains of Josephson junctions. Part II: directed aggregation on the Bethe lattice

International Nuclear Information System (INIS)

Bradley, R.M.

1985-01-01

Part I studies the effect of quantum fluctuations of the phase on the low temperature behavior of two models of Josephson junction chains with Coulomb interactions taken into account. The first model, which represents a chain of junctions close to a ground plane, is the Hamiltonian version of the two-dimensional XY model in one space and one time dimension. In the second model, the charging energy for a single junction in the chain is just the parallel-plate capacitor energy. It is shown that quantum fluctuations produce exponential decay of the order parameter correlation junction for any finite value of the junction capacitance. Part II deals with two types of directed aggregation on the Bethe lattice - directed diffusion-limited aggregation DDLA and ballistic aggregation (BA). In the DDLA problem on finite lattices, an exact nonlinear recursion relation is constructed for the probability distribution of the density. The mean density tends to zero as the lattice size is taken into infinity. Using a mapping between the model with perfect adhesion on contact and another model with a particular value of the adhesion probability, it is shown that the adhesion probability is irrelevant over an interval of values

Design of site specific radiopharmaceuticals for tumor imaging. (Parts I and II)

International Nuclear Information System (INIS)

Van Dort, M.E.

1983-01-01

Part I. Synthetic methods were developed for the preparation of several iodinated benzoic acid hydrazides as labeling moieties for indirect tagging of carbonyl-containing bio-molecules and potential tumor-imaging agents. Biodistribution studies conducted in mice on the derivatives having the I-125 label ortho to a phenolic OH demonstrated a rapid in vivo deiodination. Part II. The reported high melanin binding affinity of quinoline and other heterocyclic antimalarial drugs led to the development of many analogues of such molecules as potential melanoma-imaging agents. Once such analogue iodochloroquine does exhibit high melanin binding, but has found limited clinical use due to appreciable accumulation in non-target tissues such as the adrenal cortex and inner ear. This project developed a new series of candidate melanoma imaging agents which would be easier to radio-label, could yield higher specific activity product, and which might demonstrate more favorable pharmacokinetic and dosimetric characteristics compared to iodochloroquine

Developing guidelines for economic evaluation of environmental impacts in EIAs. Part II: Case studies and dose-response literature

International Nuclear Information System (INIS)

2005-01-01

This Part II of the report contains full versions of the case studies for air, water and land (Chapters 2-4), which were only summarised in Part I. In addition, during the work the research team has collected a large amount of literature and information on dose response relationships for air and water pollution relevant to China. This information is included as Chapters 5 and 6

Developing guidelines for economic evaluation of environmental impacts in EIAs. Part II: Case studies and dose-response literature

Energy Technology Data Exchange (ETDEWEB)

NONE

2005-07-01

This Part II of the report contains full versions of the case studies for air, water and land (Chapters 2-4), which were only summarised in Part I. In addition, during the work the research team has collected a large amount of literature and information on dose response relationships for air and water pollution relevant to China. This information is included as Chapters 5 and 6.

Repository Planning, Design, and Engineering: Part II-Equipment and Costing.

Science.gov (United States)

Baird, Phillip M; Gunter, Elaine W

2016-08-01

Part II of this article discusses and provides guidance on the equipment and systems necessary to operate a repository. The various types of storage equipment and monitoring and support systems are presented in detail. While the material focuses on the large repository, the requirements for a small-scale startup are also presented. Cost estimates and a cost model for establishing a repository are presented. The cost model presents an expected range of acquisition costs for the large capital items in developing a repository. A range of 5,000-7,000 ft(2) constructed has been assumed, with 50 frozen storage units, to reflect a successful operation with growth potential. No design or engineering costs, permit or regulatory costs, or smaller items such as the computers, software, furniture, phones, and barcode readers required for operations have been included.

Three Mile Island: a report to the commissioners and to the public. Volume II, Part 1

International Nuclear Information System (INIS)

1979-01-01

This is part one of three parts of the second volume of the Special Inquiry Group's report to the Nuclear Regulatory Commission on the accident at Three Mile Island. The first volume contained a narrative description of the accident and a discussion of the major conclusions and recommendations. This second volume is divided into three parts. Part 1 of Volume II focuses on the pre-accident licensing and regulatory background. This part includes an examination of the overall licensing and regulatory system for nuclear powerplants viewed from different perspectives: the system as it is set forth in statutes and regulations, as described in Congressional testimony, and an overview of the system as it really works. In addition, Part 1 includes the licensing, operating, and inspection history of Three Mile Island Unit 2, discussions of relevant regulatory matters, a discussion of specific precursor events related to the accident, a case study of the pressurizer design issue, and an analysis of incentives to declare commercial operation

Market Analysis and Consumer Impacts Source Document. Part II. Review of Motor Vehicle Market and Consumer Expenditures on Motor Vehicle Transportation

Science.gov (United States)

1980-12-01

This source document on motor vehicle market analysis and consumer impacts consists of three parts. Part II consists of studies and review on: motor vehicle sales trends; motor vehicle fleet life and fleet composition; car buying patterns of the busi...

Quantitative impact of aerosols on numerical weather prediction. Part II: Impacts to IR radiance assimilation

Science.gov (United States)

Marquis, J. W.; Campbell, J. R.; Oyola, M. I.; Ruston, B. C.; Zhang, J.

2017-12-01

This is part II of a two-part series examining the impacts of aerosol particles on weather forecasts. In this study, the aerosol indirect effects on weather forecasts are explored by examining the temperature and moisture analysis associated with assimilating dust contaminated hyperspectral infrared radiances. The dust induced temperature and moisture biases are quantified for different aerosol vertical distribution and loading scenarios. The overall impacts of dust contamination on temperature and moisture forecasts are quantified over the west coast of Africa, with the assistance of aerosol retrievals from AERONET, MPL, and CALIOP. At last, methods for improving hyperspectral infrared data assimilation in dust contaminated regions are proposed.

Charged-particle thermonuclear reaction rates: IV. Comparison to previous work

International Nuclear Information System (INIS)

Iliadis, C.; Longland, R.; Champagne, A.E.; Coc, A.

2010-01-01

We compare our Monte Carlo reaction rates (see Paper II of this issue) to previous results that were obtained by using the classical method of computing thermonuclear reaction rates. For each reaction, the comparison is presented using two types of graphs: the first shows the change in reaction rate uncertainties, while the second displays our new results normalized to the previously recommended reaction rate. We find that the rates have changed significantly for almost all reactions considered here. The changes are caused by (i) our new Monte Carlo method of computing reaction rates (see Paper I of this issue), and (ii) newly available nuclear physics information (see Paper III of this issue).

International Working Group on Fast Reactors Eight Annual Meeting, Vienna, Austria, 15-18 April 1975. Summary Report. Part II

International Nuclear Information System (INIS)

1975-07-01

The Eighth Annual Meeting of the IAEA International Working Group on Past Reactors was held at the IAEA Headquarters in Vienna, Austria, from 15 to 18 April 1975. The Summary Report (Part I) contains the Minutes of the Meeting. The Summary Report (Part II) contains the papers which review the national programmes in the field of LMPBR’s and other presentations at the Meeting. The Summary Report (Part III) contains the discussions on the review of the national programmes

Social class, political power, and the state: their implications in medicine--parts I and II.

Science.gov (United States)

Navarro, V

1976-01-01

This three part article presents an anlysis of the distribution of power and of the nature of the state in Western industrialized societies and details their implications in medicine. Part I presents a critique of contemporary theories of the Western system of power; discusses the countervailing pluralist and power elite theories, as well as those of bureaucratic and professional control; and concludes with an examination of the Marxist theories of economic determinism, structural determinism, and corporate statism. Part II presents a Marxist theory of the role, nature, and characteristics of state intervention. Part III (which will appear in the next issue of this journal) focuses on the mode of that intervention and the reasons for its growth, with an added analysis of the attributes of state intervention in the health sector, and of the dialectical relationship between its growth and the current fiscal crisis of the state. In all three parts, the focus is on Western European countries and on North America, with many examples and categories from the area of medicine.

Reforming Science Education: Part II. Utilizing Kieran Egan's Educational Metatheory

Science.gov (United States)

Schulz, Roland M.

2009-04-01

This paper is the second of two parts and continues the conversation which had called for a shift in the conceptual focus of science education towards philosophy of education, with the requirement to develop a discipline-specific “philosophy” of science education. In Part I, conflicting conceptions of science literacy were identified with disparate “visions” tied to competing research programs as well as school-based curricular paradigms. The impasse in the goals of science education and thereto, the contending views of science literacy, were themselves associated with three underlying fundamental aims of education (knowledge-itself; personal development; socialization) which, it was argued, usually undercut the potential of each other. During periods of “crisis-talk” and throughout science educational history these three aims have repeatedly attempted to assert themselves. The inability of science education research to affect long-term change in classrooms was correlated not only to the failure to reach a consensus on the aims (due to competing programs and to the educational ideologies of their social groups), but especially to the failure of developing true educational theories (largely neglected since Hirst). Such theories, especially metatheories, could serve to reinforce science education’s growing sense of academic autonomy and independence from socio-economic demands. In Part II, I offer as a suggestion Egan’s cultural-linguistic theory as a metatheory to help resolve the impasse. I hope to make reformers familiar with his important ideas in general, and more specifically, to show how they can complement HPS rationales and reinforce the work of those researchers who have emphasized the value of narrative in learning science.

Advances in Knowledge Discovery and Data Mining 21st Pacific Asia Conference, PAKDD 2017 Held in Jeju, South Korea, May 23 26, 2017. Proceedings Part I, Part II.

Science.gov (United States)

2017-06-27

Data Mining 21’’ Pacific-Asia Conference, PAKDD 2017Jeju, South Korea, May 23-26, Sb. GRANT NUMBER 2017 Proceedings, Part I, Part II Sc. PROGRAM...Springer; Switzerland. 14. ABSTRACT The Pacific-Asia Conference on Knowledge Discovery and Data Mining (PAKDD) is a leading international conference...in the areas of knowledge discovery and data mining (KDD). We had three keynote speeches, delivered by Sang Cha from Seoul National University

(II) complexes

African Journals Online (AJOL)

activities of Schiff base tin (II) complexes. Neelofar1 ... Conclusion: All synthesized Schiff bases and their Tin (II) complexes showed high antimicrobial and ...... Singh HL. Synthesis and characterization of tin (II) complexes of fluorinated Schiff bases derived from amino acids. Spectrochim Acta Part A: Molec Biomolec.

HERBICIDAS INIBIDORES DO FOTOSSISTEMA II – PARTE I /\tPHOTOSYSTEM II INHIBITOR HERBICIDES - PART I

Directory of Open Access Journals (Sweden)

ILCA P. DE F. E SILVA

2013-11-01

Full Text Available O controle químico tem sido o mais utilizado em grandes áreas de plantio, principalmente por ser um método rápido e eficiente. Os herbicidas inibidores do fotossistema II (PSII são fundamentais para o manejo integrado de plantas daninhas e práticas conservacionista de solo. A aplicação é realizada em pré-emergência ou pós-emergência inicial das plantas daninhas. A absorção é pelas raízes, tendo como barreira as estrias de Caspari, sendo a translocação realizada pelo xilema. O processo de absorção e translocação também são dependentes das próprias características do produto, como as propriedades lipofílicas e hidrofílicas, as quais podem ser medidas através do coeficiente de partição octanol-água (Kow. A inibição da fotossíntese acontece pela ligação dos herbicidas deste grupo ao sítio de ligação da QB, na proteína D1 do fotossistema II, o qual se localiza na membrana dos tilacóides dos cloroplastos, causando, o bloqueia do transporte de elétrons da QA para QB, interrompendo a fixação do CO2 e a produção de ATP e NAPH2.

Societal Planning: Identifying a New Role for the Transport Planner-Part II: Planning Guidelines

DEFF Research Database (Denmark)

Khisty, C. Jotin; Leleur, Steen

1997-01-01

The paper seeks to formulate planning guidelines based on Habermas's theory of communicative action. Specifically, this has led to the formulation of a set of four planning validity claims concerned to four types of planning guidelines concerning adequacy, dependency, suitability and adaptability......-a-vis the planning validity claims. Among other things the contingency of this process is outlined. It is concluded (part I & II) that transport planners can conveniently utilize the guidelines in their professional practice, tailored to their particular settings....

Unknown facets of Well-Known Scientists Series - Part II

Directory of Open Access Journals (Sweden)

V S Dixit

2016-01-01

Full Text Available 1st in the series of articles on “Unknown Facets of well-known Scientists” was about Sir Frederick Grant Banting, co-discoverer of Insulin, who also researched in Aviation and Diving Medicines, results of which brought extraordinary benefits for Flight crew during the World War II. The article was published in the previous issue of the Journal Unknown facets could be celebrated attributes, talents or otherwise, but it is necessary that we get to know fully about the “great mind". THIS ARTICLE IS ABOUT DR WERNER THEODOR OTTO FORSSMANN, A CARDIOLOGIST, WHO BECAME A UROLOGIST! Does the name Dr Forssmann ring a bell? He shared the 1956 Nobel Prize in Physiology or Medicine with “Andre Cournand and Dickinson Richards". The trio was awarded for their “discoveries concerning heart catheterization and pathological changes in the circulatory system". Dr Forssmann was nominated for performing an experiment in which he introduced a catheter into a vein of his arm, further passing it onward into his heart It was risky. This was in the year 1929. Subject of this article is the self-experimentation he carried out and what happened later.

Two-loop renormalization in the standard model, part II. Renormalization procedures and computational techniques

Energy Technology Data Exchange (ETDEWEB)

Actis, S. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Passarino, G. [Torino Univ. (Italy). Dipt. di Fisica Teorica; INFN, Sezione di Torino (Italy)

2006-12-15

In part I general aspects of the renormalization of a spontaneously broken gauge theory have been introduced. Here, in part II, two-loop renormalization is introduced and discussed within the context of the minimal Standard Model. Therefore, this paper deals with the transition between bare parameters and fields to renormalized ones. The full list of one- and two-loop counterterms is shown and it is proven that, by a suitable extension of the formalism already introduced at the one-loop level, two-point functions suffice in renormalizing the model. The problem of overlapping ultraviolet divergencies is analyzed and it is shown that all counterterms are local and of polynomial nature. The original program of 't Hooft and Veltman is at work. Finite parts are written in a way that allows for a fast and reliable numerical integration with all collinear logarithms extracted analytically. Finite renormalization, the transition between renormalized parameters and physical (pseudo-)observables, are discussed in part III where numerical results, e.g. for the complex poles of the unstable gauge bosons, are shown. An attempt is made to define the running of the electromagnetic coupling constant at the two-loop level. (orig.)

Nuclear physics II

International Nuclear Information System (INIS)

Elze, T.

1988-01-01

This script consisting of two parts contains the matter of the courses Nuclear Pyhsics I and II, as they were presented in the winter term 1987/88 and summer term 1988 for students of physics at Frankfurt University. In the present part II the matter of the summer term is summarized. (orig.) [de

Roots/Routes: Part II

Science.gov (United States)

Swanson, Dalene M.

2009-01-01

This narrative acts as an articulation of a journey of many routes. Following Part I of the same research journey of rootedness/routedness, it debates the nature of transformation and transcendence beyond personal and political paradoxes informed by neoliberalism and related repressive globalizing discourses. Through a more personal, descriptive,…

Light echoes - Type II supernovae

International Nuclear Information System (INIS)

Schaefer, B.E.

1987-01-01

Type II supernovae (SNs) light curves show a remarkable range of shapes. Data have been collected for the 12 Type II SNs that have light curve information for more than four months past maximum. Contrary to previous reports, it is found that (1) the decay rate after 100 days past maximum varies by almost an order of magnitude and (2) the light curve shapes are not bimodally distributed, but actually form a continuum. In addition, it is found that the extinctions to the SNs are related to the light curve shapes. This implies that the absorbing dust is local to the SNs. The dust is likely to be part of a circumstellar shell emitted by the SN progenitor that Dwek (1983) has used to explain infrared echoes. The optical depth of the shell can get quite large. In such cases, it is found that the photons scattered and delayed by reflection off dust grains will dominate the light curve several months after peak brightness. This light echo offers a straightforward explanation of the diversity of Type II SN light curves. 22 references

One-loop effective actions and higher spins. Part II

Science.gov (United States)

Bonora, L.; Cvitan, M.; Prester, P. Dominis; Giaccari, S.; Štemberga, T.

2018-01-01

In this paper we continue and improve the analysis of the effective actions obtained by integrating out a scalar and a fermion field coupled to external symmetric sources, started in the previous paper. The first subject we study is the geometrization of the results obtained there, that is we express them in terms of covariant Jacobi tensors. The second subject concerns the treatment of tadpoles and seagull terms in order to implement off-shell covariance in the initial model. The last and by far largest part of the paper is a repository of results concerning all two point correlators (including mixed ones) of symmetric currents of any spin up to 5 and in any dimensions between 3 and 6. In the massless case we also provide formulas for any spin in any dimension.

Programming an interim report on the SETL project. Part I: generalities. Part II: the SETL language and examples of its use

Energy Technology Data Exchange (ETDEWEB)

Schwartz, J T

1975-06-01

A summary of work during the past several years on SETL, a new programming language drawing its dictions and basic concepts from the mathematical theory of sets, is presented. The work was started with the idea that a programming language modeled after an appropriate version of the formal language of mathematics might allow a programming style with some of the succinctness of mathematics, and that this might ultimately enable one to express and experiment with more complex algorithms than are now within reach. Part I discusses the general approach followed in the work. Part II focuses directly on the details of the SETL language as it is now defined. It describes the facilities of SETL, includes short libraries of miscellaneous and of code optimization algorithms illustrating the use of SETL, and gives a detailed description of the manner in which the set-theoretic primitives provided by SETL are currently implemented. (RWR)

Field Surveys, IOC Valleys. Volume III, Part II. Cultural Resources Survey, Pine and Wah Wah Valleys, Utah.

Science.gov (United States)

1981-08-01

including horse, camel, mammoth, Ertm E-TR-48-III-II 20 musk ox, and certain species of bison, goat, and bear, which had previously inhabited the marsh and...34 - - -9,$.. 𔄃 Im I I I Si to * Location lype/Contents Affiliation 42B@644 rid e over cr ek - P/J depression, cleared areas, Fr elon (f4-5-18-92) ground

Fractional Programming for Communication Systems—Part II: Uplink Scheduling via Matching

Science.gov (United States)

Shen, Kaiming; Yu, Wei

2018-05-01

This two-part paper develops novel methodologies for using fractional programming (FP) techniques to design and optimize communication systems. Part I of this paper proposes a new quadratic transform for FP and treats its application for continuous optimization problems. In this Part II of the paper, we study discrete problems, such as those involving user scheduling, which are considerably more difficult to solve. Unlike the continuous problems, discrete or mixed discrete-continuous problems normally cannot be recast as convex problems. In contrast to the common heuristic of relaxing the discrete variables, this work reformulates the original problem in an FP form amenable to distributed combinatorial optimization. The paper illustrates this methodology by tackling the important and challenging problem of uplink coordinated multi-cell user scheduling in wireless cellular systems. Uplink scheduling is more challenging than downlink scheduling, because uplink user scheduling decisions significantly affect the interference pattern in nearby cells. Further, the discrete scheduling variable needs to be optimized jointly with continuous variables such as transmit power levels and beamformers. The main idea of the proposed FP approach is to decouple the interaction among the interfering links, thereby permitting a distributed and joint optimization of the discrete and continuous variables with provable convergence. The paper shows that the well-known weighted minimum mean-square-error (WMMSE) algorithm can also be derived from a particular use of FP; but our proposed FP-based method significantly outperforms WMMSE when discrete user scheduling variables are involved, both in term of run-time efficiency and optimizing results.

Noncardiac findings on cardiac CT. Part II: spectrum of imaging findings.

LENUS (Irish Health Repository)

Killeen, Ronan P

2012-02-01

Cardiac computed tomography (CT) has evolved into an effective imaging technique for the evaluation of coronary artery disease in selected patients. Two distinct advantages over other noninvasive cardiac imaging methods include its ability to directly evaluate the coronary arteries and to provide a unique opportunity to evaluate for alternative diagnoses by assessing the extracardiac structures, such as the lungs and mediastinum, particularly in patients presenting with the chief symptom of acute chest pain. Some centers reconstruct a small field of view (FOV) cropped around the heart but a full FOV (from skin to skin in the area irradiated) is obtainable in the raw data of every scan so that clinically relevant noncardiac findings are identifiable. Debate in the scientific community has centered on the necessity for this large FOV. A review of noncardiac structures provides the opportunity to make alternative diagnoses that may account for the patient\\'s presentation or to detect important but clinically silent problems such as lung cancer. Critics argue that the yield of biopsy-proven cancers is low and that the follow-up of incidental noncardiac findings is expensive, resulting in increased radiation exposure and possibly unnecessary further testing. In this 2-part review we outline the issues surrounding the concept of the noncardiac read, looking for noncardiac findings on cardiac CT. Part I focused on the pros and cons for and against the practice of identifying noncardiac findings on cardiac CT. Part II illustrates the imaging spectrum of cardiac CT appearances of benign and malignant noncardiac pathology.

The Historiography of British Imperial Education Policy, Part II: Africa and the Rest of the Colonial Empire

Science.gov (United States)

Whitehead, Clive

2005-01-01

Part II of this historiographical study examines British education policy in Africa, and in the many crown colonies, protectorates, and mandated territories around the globe. Up until 1920, the British government took far less interest than in India, in the development of schooling in Africa and the rest of the colonial empire, and education was…

DOE program guide for universities and other research groups. Part I. DOE Research and Development Programs; Part II. DOE Procurement and Assistance Policies/Procedures

Energy Technology Data Exchange (ETDEWEB)

1980-03-01

This guide addresses the DOE responsibility for fostering advanced research and development of all energy resources, both current and potential. It is intended to provide, in a single publication, all the fundamental information needed by an institution to develop a potential working relationship with DOE. Part I describes DOE research and development programs and facilities, and identifies areas of additional research needs and potential areas for new research opportunities. It also summarizes budget data and identifies the DOE program information contacts for each program. Part II provides researchers and research administrators with an introduction to the DOE administrative policies and procedures for submission and evaluation of proposals and the administration of resulting grants, cooperative agreements, and research contracts. (RWR)

Assessing and addressing moral distress and ethical climate Part II: neonatal and pediatric perspectives.

Science.gov (United States)

Sauerland, Jeanie; Marotta, Kathleen; Peinemann, Mary Anne; Berndt, Andrea; Robichaux, Catherine

2015-01-01

Moral distress remains a pervasive and, at times, contested concept in nursing and other health care disciplines. Ethical climate, the conditions and practices in which ethical situations are identified, discussed, and decided, has been shown to exacerbate or ameliorate perceptions of moral distress. The purpose of this mixed-methods study was to explore perceptions of moral distress, moral residue, and ethical climate among registered nurses working in an academic medical center. Two versions of the Moral Distress Scale in addition to the Hospital Ethical Climate Survey were used, and participants were invited to respond to 2 open-ended questions. Part I reported the findings among nurses working in adult acute and critical care units. Part II presents the results from nurses working in pediatric/neonatal units. Significant differences in findings between the 2 groups are discussed. Subsequent interventions developed are also presented.

Phase I/II study of gefitinib (Iressa(®)) and vorinostat (IVORI) in previously treated patients with advanced non-small cell lung cancer.

Science.gov (United States)

Han, Ji-Youn; Lee, Soo Hyun; Lee, Geon Kook; Yun, Tak; Lee, Young Joo; Hwang, Kum Hui; Kim, Jin Young; Kim, Heung Tae

2015-03-01

Vorinostat has been shown to overcome resistance to gefitinib. We performed a phase I/II study combining gefitinib with vorinostat in previously treated non-small cell lung cancer (NSCLC). A 3 + 3 dose-escalation design was used to determine maximum tolerated dose (MTD) and recommended phase II dose (RP2D). Three dose levels were tested: 250 mg/day gefitinib on days 1-28 and 200, 300 or 400 mg/day vorinostat on days 1-7, and 15-21 out of every 28 days. The primary endpoint was median progression-free survival (PFS). Fifty-two patients were enrolled and treated (43 in phase II). The median age was 59 years, 28 patients were male, 44 had adenocarcinoma, 29 had never smoked, and 36 had undergone one prior treatment. Twenty-two patients exhibited sensitive EGFR mutations. Planned dose escalation was completed without reaching the MTD. The RP2D was 250 mg gefitinib and 400 mg vorinostat. In 43 assessable patients in phase II, the median PFS was 3.2 months; the overall survival (OS) was 19.0 months. There were 16 partial responses and six cases of stable disease. In EGFR-mutant NSCLC, response rate was 77 %, median PFS was 9.1 months, and median OS was 24.1 months. The most common adverse events were anorexia and diarrhea. Treatment with 250 mg gefitinib daily with biweekly 400 mg/day vorinostat was feasible and well tolerated. In an unselected patient population, this combination dose did not improve PFS. However, this combination showed a potential for improving efficacy of gefitinib in EGFR-mutant NSCLC (NCT01027676).

Mineral resources of parts of the Departments of Antioquia and Caldas, Zone II, Colombia

Science.gov (United States)

Hall, R.B.; Feininger, Tomas; Barrero, L.; Dario, Rico H.; ,; Alvarez, A.

1970-01-01

The mineral resources of an area of 40,000 sq km, principally in the Department of Antioquia, but including small parts of the Departments of Caldas, C6rdoba, Risaralda, and Tolima, were investigated during the period 1964-68. The area is designated Zone II by the Colombian Inventario Minero Nacional(lMN). The geology of approximately 45 percent of this area, or 18,000 sq km, has been mapped by IMN. Zone II has been a gold producer for centuries, and still produces 75 percent of Colombia's gold. Silver is recovered as a byproduct. Ferruginous laterites have been investigated as potential sources of iron ore but are not commercially exploitable. Nickeliferous laterite on serpentinite near Ure in the extreme northwest corner of the Zone is potentially exploitable, although less promising than similar laterites at Cerro Matoso, north of the Zone boundary. Known deposits of mercury, chromium, manganese, and copper are small and have limited economic potentia1. Cement raw materials are important among nonmetallic resources, and four companies are engaged in the manufacture of portland cement. The eastern half of Zone II contains large carbonate rock reserves, but poor accessibility is a handicap to greater development at present. Dolomite near Amalfi is quarried for the glass-making and other industries. Clay saprolite is abundant and widely used in making brick and tiles in backyard kilns. Kaolin of good quality near La Union is used by the ceramic industry. Subbituminous coal beds of Tertiary are an important resource in the western part of the zone and have good potential for greater development. Aggregate materials for construction are varied and abundant. Deposits of sodic feldspar, talc, decorative stone, and silica are exploited on a small scale. Chrysotils asbestos deposits north of Campamento are being developed to supply fiber for Colombia's thriving asbestos-cement industry, which is presently dependent upon imported fiber. Wollastonite and andalusite are

Mission Plan for the Civilian Radioactive Waste Management Program. Volume I. Part I. Overview and current program plans; Part II. Information required by the Nuclear Waste Policy Act of 1982

International Nuclear Information System (INIS)

1985-06-01

The Misson Plan is divided into two parts. Part I describes the overall goals, objectives, and strategy for the disposal of spent nuclear fuel and high-level waste. It explains that, to meet the directives of the Nuclear Waste Policy Act, the DOE intends to site, design, construct, and start operating a mined geologic repository by January 31, 1998. The Act specifies that the costs of these activities will be borne by the owners and generators of the waste received at the repository. Part I further describes the other components of the waste-management program - monitored retrievable storage, Federal interim storage, and transportation - as well as systems integration activities. Also discussed are institutional plans and activities as well as the program-management system being implemented by the Office of Civilian Radioactive Waste Management. Part II of the Mission Plan presents the detailed information required by Section 301(a) of the Act - key issues and information needs; plans for obtaining the necessary information; potential financial, institutional, and legal issues; plans for the test and evaluation facility; the principal results obtained to date from site investigations; information on the site-characterization programs; information on the waste package; schedules; costs; and socioeconomic impacts. In accordance with Section 301(a) of the Act, Part II is concerned primarily with the repository program

Nuclear power plant simulators for operator licensing and training. Part I. The need for plant-reference simulators. Part II. The use of plant-reference simulators

International Nuclear Information System (INIS)

Rankin, W.L.; Bolton, P.A.; Shikiar, R.; Saari, L.M.

1984-05-01

Part I of this report presents technical justification for the use of plant-reference simulators in the licensing and training of nuclear power plant operators and examines alternatives to the use of plant-reference simulators. The technical rationale is based on research on the use of simulators in other industries, psychological learning and testing principles, expert opinion and user opinion. Part II discusses the central considerations in using plant-reference simulators for licensing examination of nuclear power plant operators and for incorporating simulators into nuclear power plant training programs. Recommendations are presented for the administration of simulator examinations in operator licensing that reflect the goal of maximizing both reliability and validity in the examination process. A series of organizational tasks that promote the acceptance, use, and effectiveness of simulator training as part of the onsite training program is delineated

Magnetite Dissolution Performance of HYBRID-II Decontamination Process

International Nuclear Information System (INIS)

Kim, Seonbyeong; Lee, Woosung; Won, Huijun; Moon, Jeikwon; Choi, Wangkyu

2014-01-01

In this study, we conducted the magnetite dissolution performance test of HYBRID-II (Hydrazine Based Reductive metal Ion Decontamination with sulfuric acid) as a part of decontamination process development. Decontamination performance of HYBRID process was successfully tested with the results of the acceptable decontamination factor (DF) in the previous study. While following-up studies such as the decomposition of the post-decontamination HYBRID solution and corrosion compatibility on the substrate metals of the target reactor coolant system have been continued, we also seek for an alternate version of HYBRID process suitable especially for decommissioning. Inspired by the relationship between the radius of reacting ion and the reactivity, we replaced the nitrate ion in HYBRID with bigger sulfate ion to accommodate the dissolution reaction and named HYBRID-II process. As a preliminary step for the decontamination performance, we tested the magnetite dissolution performance of developing HYBRID-II process and compared the results with those of HYBRID process. HYBRID process developed previously is known have the acceptable decontamination performance, but the relatively larger volume of secondary waste induced by anion exchange resin to treat nitrate ion is the one of the problems related in the development of HYBRID process to be applicable. Therefore we alternatively devised HYBRID-II process using sulfuric acid and tested its dissolution of magnetite in numerous conditions. From the results shown in this study, we can conclude that HYBRID-II process improves the decontamination performance and potentially reduces the volume of secondary waste. Rigorous tests with metal oxide coupons obtained from reactor coolant system will be followed to prove the robustness of HYBRID-II process in the future

[Evaluation of serum PIVKA-II by Lumipulse PrestoII assay].

Science.gov (United States)

Hiramatsu, Kumiko; Tanaka, Yasuhito; Takagi, Kazumi; Kani, Satomi; Goto, Takaaki; Takasaka, Yoshimitsu; Matsuura, Kentaro; Sugauchi, Fuminaka; Moriyama, Kazushige; Murakami, Hiroshi; Kitajima, Sachiko; Mizokami, Masashi

2009-03-01

Measurements of serum concentrations of Des-gamma-carboxy Prothrombin (PIVKA-II) are widely used for diagnosing hepatocellular carcinoma (HCC). Recently, in Lumipulsef assay, it was reported that antibodies against alkaline phosphatase (ALP) derived from anti bleeding sheets led false high values of PIVKA-II in the patients with HCC resection. To improve the previous issue, newly developed Lumipulse PrestoII assay was examined. (1) The assay was reliable and positively correlated with the previous assays (Lumipulse f and Picolumi, R = 0.997 and 0.994 (n=115), respectively). (2) Eleven cases, which had false high values of PIVKA-II by the Lumipulsef assay, were examined by the PrestoII assay with excess of inactive ALP. The false high values of 10 cases were improved, but only one was still high. False reactivity of this case was stronger than other cases, more effective adsorption was required. (3) Comparing the absorbent activity of inactive ALP among 6 different kinds, we found inactive ALP with much higher adsorbent activity. When this inactive ALP was applied to assay, false high values of PIVKA-II were improved in all 11 cases. In conclusion, the PrestoII assay, which applies the inactive ALP with high activity, is reliable and useful for clinical screening.

Transferring diffractive optics from research to commercial applications: Part II - size estimations for selected markets

Science.gov (United States)

Brunner, Robert

2014-04-01

In a series of two contributions, decisive business-related aspects of the current process status to transfer research results on diffractive optical elements (DOEs) into commercial solutions are discussed. In part I, the focus was on the patent landscape. Here, in part II, market estimations concerning DOEs for selected applications are presented, comprising classical spectroscopic gratings, security features on banknotes, DOEs for high-end applications, e.g., for the semiconductor manufacturing market and diffractive intra-ocular lenses. The derived market sizes are referred to the optical elements, itself, rather than to the enabled instruments. The estimated market volumes are mainly addressed to scientifically and technologically oriented optical engineers to serve as a rough classification of the commercial dimensions of DOEs in the different market segments and do not claim to be exhaustive.

Adaptive Core Simulation Employing Discrete Inverse Theory - Part II: Numerical Experiments

International Nuclear Information System (INIS)

Abdel-Khalik, Hany S.; Turinsky, Paul J.

2005-01-01

Use of adaptive simulation is intended to improve the fidelity and robustness of important core attribute predictions such as core power distribution, thermal margins, and core reactivity. Adaptive simulation utilizes a selected set of past and current reactor measurements of reactor observables, i.e., in-core instrumentation readings, to adapt the simulation in a meaningful way. The companion paper, ''Adaptive Core Simulation Employing Discrete Inverse Theory - Part I: Theory,'' describes in detail the theoretical background of the proposed adaptive techniques. This paper, Part II, demonstrates several computational experiments conducted to assess the fidelity and robustness of the proposed techniques. The intent is to check the ability of the adapted core simulator model to predict future core observables that are not included in the adaption or core observables that are recorded at core conditions that differ from those at which adaption is completed. Also, this paper demonstrates successful utilization of an efficient sensitivity analysis approach to calculate the sensitivity information required to perform the adaption for millions of input core parameters. Finally, this paper illustrates a useful application for adaptive simulation - reducing the inconsistencies between two different core simulator code systems, where the multitudes of input data to one code are adjusted to enhance the agreement between both codes for important core attributes, i.e., core reactivity and power distribution. Also demonstrated is the robustness of such an application

Epidemiological situation of tuberculosis in Poland: part II. What are the causes of the different epidemiological situation in various regions of Poland?

Science.gov (United States)

Rowińska-Zakrzewska, Ewa; Korzeniewska-Koseła, Maria; Roszkowski-Śliż, Kazimierz

2014-01-01

The different epidemiological situation of tuberculosis in various regions of Poland (higher and lower notification rates) was described previously by our group. The patients diagnosed with tuberculosis in the higher notification rate areas were younger and there were more cases of primary tuberculosis (tuberculous pleurisy and tuberculosis of chest lymph nodes) than in the patients diagnosed in the lower notification areas. The aim of the present study was to assess the possible causes of the different epidemiological situation of tuberculosis in various regions of Poland. Analysis was done at the same regions as in the previous paper. A comparison was made between two groups: Group I, which included three voivodeships with higher rates of notification, from 23.7 to 32.3/100,000 (mean rates in the analysed period of time); and Group II, which included five voivodeships with lower notification rates (mean rates from 12.2 to 18.6/100,000). The wealth of the regions (GDP, gross domestic product per capita), the level of unemployment, and social status of the patients were analysed. We compared the population density in both regions. The results of treatment in both regions were also analysed. We did not find any differences in GDP and unemployment rates between the compared regions. The results of treatment were different in particular regions, but there was no clear tendency for worse results in voivodeships in Group I compared to voivodeships in Group II. However, the number of patients lost from observation was significantly higher in the regions from Group I than in those from Group II. There was also a significantly higher death rate from tuberculosis in younger patients (£ 59 years) from Group I than from Group II. This is additional proof that the epidemiological situation in the two regions was different. Finally, we found that the mean density of population in the regions from Group I was higher than that from Group II. The density of population may

Coal-fired power materials - Part II

Energy Technology Data Exchange (ETDEWEB)

Viswanathan, V.; Purgert, R.; Rawls, P. [Electric Power Research Institute, Palo Alto, CA (United States)

2008-09-15

Part 1 discussed some general consideration in selection of alloys for advanced ultra supercritical (USC) coal-fired power plant boilers. This second part covers results reported by the US project consortium, which has extensively evaluated the steamside oxidation, fireside corrosion, and fabricability of the alloys selected for USC plants. 3 figs.

[Education in our time: competency or aptitude? The case for medicine. Part II].

Science.gov (United States)

Viniegra-Velázquez, Leonardo

Part II is focused on participatory education (PE), a distinctive way to understand and practice education in contrast to passive education. The core of PE is to develop everyone's own cognitive potentialities frequently mutilated, neglected or ignored. Epistemological and experiential basis of PE are defined: the concept of incisive and creative criticism, the idea of knowledge as each person's own construct and life experience as the main focus of reflection and cognition. The PE aims towards individuals with unprecedented cognitive and creative faculties, capable of approaching a more inclusive and hospitable world. The last part criticizes the fact that medical education has remained among the passive education paradigm. The key role of cognitive aptitudes, both methodological and practical (clinical aptitude), in the progress of medical education and practice is emphasized. As a conclusion, the knowhow of education is discussed, aiming towards a better world away from human and planetary degradation. Copyright © 2017 Hospital Infantil de México Federico Gómez. Publicado por Masson Doyma México S.A. All rights reserved.

Curcumin and Cholecalciferol in Treating Patients With Previously Untreated Stage 0-II Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Science.gov (United States)

2018-01-26

Contiguous Stage II Small Lymphocytic Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Stage 0 Chronic Lymphocytic Leukemia; Stage I Chronic Lymphocytic Leukemia; Stage I Small Lymphocytic Lymphoma; Stage II Chronic Lymphocytic Leukemia

Stiffnites. Part II

Directory of Open Access Journals (Sweden)

Maria Teresa Pareschi

2011-06-01

Full Text Available

The dynamics of a stiffnite are here inferred. A stiffnite is a sheet-shaped, gravity-driven submarine sediment flow, with a fabric made up of marine ooze. To infer stiffnite dynamics, order of magnitude estimations are used. Field deposits and experiments on materials taken from the literature are also used. Stiffnites can be tens or hundreds of kilometers wide, and a few centimeters/ meters thick. They move on the sea slopes over hundreds of kilometers, reaching submarine velocities as high as 100 m/s. Hard grain friction favors grain fragmentation and formation of triboelectrically electrified particles and triboplasma (i.e., ions + electrons. Marine lipids favor isolation of electrical charges. At first, two basic assumptions are introduced, and checked a posteriori: (a in a flowing stiffnite, magnetic dipole moments develop, with the magnetization proportional to the shear rate. I have named those dipoles as Ambigua. (b Ambigua are ‘vertically frozen’ along stiffnite streamlines. From (a and (b, it follows that: (i Ambigua create a magnetic field (at peak, >1 T. (ii Lorentz forces sort stiffnite particles into two superimposed sheets. The lower sheet, L+, has a sandy granulometry and a net positive electrical charge density. The upper sheet, L–, has a silty muddy granulometry and a net negative electrical charge density; the grains of sheet L– become finer upwards. (iii Faraday forces push ferromagnetic grains towards the base of a stiffnite, so that a peak of magnetic susceptibility characterizes a stiffnite deposit. (iv Stiffnites harden considerably during their motion, due to magnetic confinement. Stiffnite deposits and inferred stiffnite characteristics are compatible with a stable flow behavior against bending, pinch, or other macro instabilities. In the present report, a consistent hypothesis about the nature of Ambigua is provided.

The T?lz Temporal Topography Study: Mapping the visual field across the life span. Part II: Cognitive factors shaping visual field maps

OpenAIRE

Poggel, Dorothe A.; Treutwein, Bernhard; Calmanti, Claudia; Strasburger, Hans

2012-01-01

Part I described the topography of visual performance over the life span. Performance decline was explained only partly by deterioration of the optical apparatus. Part II therefore examines the influence of higher visual and cognitive functions. Visual field maps for 95 healthy observers of static perimetry, double-pulse resolution (DPR), reaction times, and contrast thresholds, were correlated with measures of visual attention (alertness, divided attention, spatial cueing), visual search, an...

Human-like behavior of robot arms: general considerations and the handwriting task-part II: The robot arm in handwriting

NARCIS (Netherlands)

Potkonjak, V.; Kostic, D.; Tzafestas, S.; Popovic, M.; Lazarevic, M.; Djordjevic, G.

2001-01-01

This paper (Part II) investigates the motion of a redundant anthropomorphic arm during the writing task. Two approaches are applied. The first is based on the concept of distributed positioning which is suitable to model the "writing" task before the occurrence of fatigue symptoms. The second

Inhibition of Hsp90 acts synergistically with topoisomerase II poisons to increase the apoptotic killing of cells due to an increase in topoisomerase II mediated DNA damage.

Science.gov (United States)

Barker, Catherine R; McNamara, Anne V; Rackstraw, Stephen A; Nelson, David E; White, Mike R; Watson, Alastair J M; Jenkins, John R

2006-01-01

Topoisomerase II plays a crucial role during chromosome condensation and segregation in mitosis and meiosis and is a highly attractive target for chemotherapeutic agents. We have identified previously topoisomerase II and heat shock protein 90 (Hsp90) as part of a complex. In this paper we demonstrate that drug combinations targeting these two enzymes cause a synergistic increase in apoptosis. The objective of our study was to identify the mode of cell killing and the mechanism behind the increase in topoisomerase II mediated DNA damage. Importantly we demonstrate that Hsp90 inhibition results in an increased topoiosmerase II activity but not degradation of topoisomerase II and it is this, in the presence of a topoisomerase II poison that causes the increase in cell death. Our results suggest a novel mechanism of action where the inhibition of Hsp90 disrupts the Hsp90-topoisomerase II interaction leading to an increase in and activation of unbound topoisomerase II, which, in the presence of a topoisomerase II poison leads to the formation of an increased number of cleavable complexes ultimately resulting in rise in DNA damage and a subsequent increase cell death.

Tunable, Flexible and Efficient Optimization of Control Pulses for Superconducting Qubits, part II - Applications

Science.gov (United States)

AsséMat, Elie; Machnes, Shai; Tannor, David; Wilhelm-Mauch, Frank

In part I, we presented the theoretic foundations of the GOAT algorithm for the optimal control of quantum systems. Here in part II, we focus on several applications of GOAT to superconducting qubits architecture. First, we consider a control-Z gate on Xmons qubits with an Erf parametrization of the optimal pulse. We show that a fast and accurate gate can be obtained with only 16 parameters, as compared to hundreds of parameters required in other algorithms. We present numerical evidences that such parametrization should allow an efficient in-situ calibration of the pulse. Next, we consider the flux-tunable coupler by IBM. We show optimization can be carried out in a more realistic model of the system than was employed in the original study, which is expected to further simplify the calibration process. Moreover, GOAT reduced the complexity of the optimal pulse to only 6 Fourier components, composed with analytic wrappers.

Reproduction in the space environment: Part II. Concerns for human reproduction

Science.gov (United States)

Jennings, R. T.; Santy, P. A.

1990-01-01

Long-duration space flight and eventual colonization of our solar system will require successful control of reproductive function and a thorough understanding of factors unique to space flight and their impact on gynecologic and obstetric parameters. Part II of this paper examines the specific environmental factors associated with space flight and the implications for human reproduction. Space environmental hazards discussed include radiation, alteration in atmospheric pressure and breathing gas partial pressures, prolonged toxicological exposure, and microgravity. The effects of countermeasures necessary to reduce cardiovascular deconditioning, calcium loss, muscle wasting, and neurovestibular problems are also considered. In addition, the impact of microgravity on male fertility and gamete quality is explored. Due to current constraints, human pregnancy is now contraindicated for space flight. However, a program to explore effective countermeasures to current constraints and develop the required health care delivery capability for extended-duration space flight is suggested. A program of Earth- and space-based research to provide further answers to reproductive questions is suggested.

Mixed ligand complexes of alkaline earth metals: Part XII. Mg(II, Ca(II, Sr(II and Ba(II complexes with 5-chlorosalicylaldehyde and salicylaldehyde or hydroxyaromatic ketones

Directory of Open Access Journals (Sweden)

MITHLESH AGRAWAL

2002-04-01

Full Text Available The reactions of alkaline earth metal chlorides with 5-chlorosalicylaldehyde and salicylaldehyde, 2-hydroxyacetophenone or 2-hydroxypropiophenone have been carried out in 1 : 1 : 1 mole ratio and the mixed ligand complexes of the type MLL’(H2O2 (where M = Mg(II, Ca(II, Sr(II and Ba(II, HL = 5-chlorosalicylaldehyde and HL’ = salicylaldehyde, 2-hydroxyacetophenone or 2-hydroxypropiophenone have been isolated. These complexes were characterized by TLC, conductance measurements, IR and 1H-NMR spectra.

Part II. Population

International Nuclear Information System (INIS)

2004-01-01

This monograph deals with assessment of radiological health effects of the Chernobyl accident for emergency workers (part 1) and the population of the contaminated areas in Russia (part 2). The Chernobyl emergency workers and people living in the contaminated areas of Russia received much lower doses than the population of Hiroshima and Nagasaki and it was unclear whether risks of radiation-induced cancers derived with the Japanese data could be extrapolated to the low dose range However, it was predicted as early as in 1990 that the thyroid cancer incidence might be increasing due to incorporated 131 irradiation. What conclusions can be drawn from regarding cancer incidence among emergency workers and residents of the contaminated areas in Russia and the role of the radiation factor on the basis of the registry data? Leukemia incidence. Leukemia incidence is known to be one of principal indications of radiation effects. The radiation risk for leukemias is 3-4 times higher that for solid cancers and its latent period is estimated to be 2-3 years after exposure. Results of the radiation epidemiological studies discussed in this book show that in the worst contaminated Bryansk region the leukemia incidence rate is not higher than in the country in general. Even though some evidence exists for the dose response relationship, the radiation risks appear to be not statistically significant. Since risks of leukemia are known to be higher for those who were children at exposure, long-term epidemiological studies need to be continued. The study of leukemias among emergency workers strongly suggest the existence of dose response relationship. In those who received external doses more than 0.15 Gy the leukemia incidence rate is two time higher and these emergency workers should be referred to as a group of increased radiation risk. Solid cancers. The obtained results provide no evidence to a radiation-induced increase in solid cancers among residents of the contaminated areas

Modification of the ultrasound induced activity by the presence of an electrode in a sono-reactor working at two low frequencies (20 and 40 kHz). Part II: Mapping flow velocities by particle image velocimetry (PIV).

Science.gov (United States)

Mandroyan, A; Doche, M L; Hihn, J Y; Viennet, R; Bailly, Y; Simonin, L

2009-01-01

Sonoelectrochemical experiments differ from sonochemical ones by the introduction of electrodes in the sonicated reaction vessel. The aim of the study is to characterize the changes in the ultrasonic activity induced by the presence of an electrode located in front of the transducer. The scope of our investigations concerns two low frequency vibration modes: 20 and 40 kHz. For this purpose, two laser visualization techniques have been used. The first part of the study, described in a previous paper (Part I), deals with the laser tomography technique which provides an accurate picture of the reactor active zones, related to numerous cavitation events. The second part of the paper (Part II) will describe the particle image velocimetry (PIV) technique used to measure the velocity vector field in the fluid portion between the horn and the electrode. As for the previous study, two parameters were studied: the electrical power supplied to the transducer and the electrode/transducer distance. The velocity vector fields show a main flow in the reactor axis. This flow seems to correspond to the conical cavitation bubbles structure which is observed on the laser tomography pictures. When an electrode is introduced into the reactor, two additional symmetric transversal flows can be quantified on both sides of the electrode.

30 CFR Appendix II to Subpart D of... - Appendix II to Subpart D of Part 18

Science.gov (United States)

2010-07-01

... LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MOTOR-DRIVEN MINE EQUIPMENT AND ACCESSORIES Machines Assembled With Certified or Explosion-Proof Components, Field Modifications of Approved Machines, and Permits To Use Experimental Equipment Pt. 18, Subpt. D, App. II Appendix II to Subpart D of...

Majewski osteodysplastic primordial dwarfism type II (MOPD II) syndrome previously diagnosed as Seckel syndrome: report of a novel mutation of the PCNT gene.

Science.gov (United States)

Piane, Maria; Della Monica, Matteo; Piatelli, Gianluca; Lulli, Patrizia; Lonardo, Fortunato; Chessa, Luciana; Scarano, Gioacchino

2009-11-01

We report on a 3-year-old boy with prenatal onset of proportionate dwarfism, postnatal severe microcephaly, high forehead with receded hairline, sparse scalp hair, beaked nose, mild retrognathia and hypotonia diagnosed at birth as Seckel syndrome. At age 3 years, he became paralyzed due to a cerebrovascular malformation. Based on the clinical and radiological features showing evidence of skeletal dysplasia, the diagnosis was revised to Majewski osteodysplastic primordial dwarfism type II (MOPD II) syndrome. Western blot analysis of the patient's lymphoblastoid cell line lysate showed the absence of the protein pericentrin. Subsequent molecular analysis identified a novel homozygous single base insertion (c.1527_1528insA) in exon 10 of the PCNT gene, which leads to a frameshift (Treo510fs) and to premature protein truncation. PCNT mutations must be considered diagnostic of MOPD II syndrome. A possible role of pericentrin in the development of cerebral vessels is suggested. Copyright 2009 Wiley-Liss, Inc.

SAFEPAQ-II. User manual[Nuclear data

Energy Technology Data Exchange (ETDEWEB)

Forrest, R.A

2001-03-01

SAFEPAQ-II is the new software tool that has been developed to enable efficient production of the EAF nuclear data libraries that are required as input to the FISPACT activation code. It forms part of the European Activation System (EASY), and replaces SAFEPAQ and SYMPAL that were used previously. It enables all the nuclear data to be stored in relational databases (Access) and by using an interactive user interface allows the data to be viewed, modified, validated and then produced in the required EAF format as text files. It is written in Visual Basic and runs under the Windows NT4 and 98 operating systems. The Windows operating system has the great advantage of portability and SAFEPAQ-II has been successfully installed at two external sites for use by UKAEA's international collaborators. It has been used in the production of the EAF-2001 data libraries. (author)

Synthesis, characterization and polymerization of methacrylates of copper (II), cobalt (II) and molybdenum (II). Generation of new materials

International Nuclear Information System (INIS)

Rojas Bolanos, Omar

2006-01-01

Coordination compounds of the species copper (II), cobalt (II) and molybdenum (II) with methacrylic acid were synthesized and characterized. Besides, it realized reactions of bromine addition to the doubles links of the species obtained previously, also too like reactions with dry HCl. Finally, it got hybrids materials by polymerization of the first compounds in an acrylic matrix. Research concluded with the characterization of all the products. (author) [es

CERN scientists take part in the Tevatron Run II performance review committee

CERN Multimedia

Maximilien Brice

2002-01-01

Tevatron Run II is under way at Fermilab, exploring the high-energy frontier with upgraded detectors that will address some of the biggest questions in particle physics.Until CERN's LHC switches on, the Tevatron proton-antiproton collider is the world's only source of top quarks. It is the only place where we can search for supersymmetry, for the Higgs boson, and for signatures of additional dimensions of space-time. The US Department of Energy (DOE) recently convened a high-level international review committee to examine Fermilab experts' first-phase plans for the accelerator complex. Pictured here with a dipole magnet in CERN's LHC magnet test facility are the four CERN scientists who took part in the DOE's Tevatron review. Left to right: Francesco Ruggiero, Massimo Placidi, Flemming Pedersen, and Karlheinz Schindl. Further information: CERN Courier 43 (1)

Implementing AORN recommended practices for a safe environment of care, part II.

Science.gov (United States)

Kennedy, Lynne

2014-09-01

Construction in and around a working perioperative suite is a challenge beyond merely managing traffic patterns and maintaining the sterile field. The AORN "Recommended practices for a safe environment of care, part II" provides guidance on building design; movement of patients, personnel, supplies, and equipment; environmental controls; safety and security; and control of noise and distractions. Whether the OR suite evolves through construction, reconstruction, or remodeling, a multidisciplinary team of construction experts and health care professionals should create a functional plan and communicate at every stage of the project to maintain a safe environment and achieve a well-designed outcome. Emergency preparedness, a facility-wide security plan, and minimization of noise and distractions in the OR also help enhance the safety of the perioperative environment. Copyright © 2014 AORN, Inc. Published by Elsevier Inc. All rights reserved.

All About Dowels - A Review Part II Considerations After Cementation

Directory of Open Access Journals (Sweden)

Zishan Dangra

2017-10-01

Full Text Available The present review summarizes the published literature examining cementation of the dowel and factors related to it. The peer reviewed English language literature was reviewed from the period 1990 to 2015. Articles were searched in Pubmed/ Medline for the relevant terms. Additional manual searches of some dental journals were also carried out. The original key terms resulted in 228 articles. After applying inclusion criteria, 64 articles remained to be included in part II of this review. Article search indicates that most published literature on dowels are in the form of in vitro analysis. Literature on prefabricated dowel systems far exceeds than the custom cast dowel and newer fibre dowels. Clinical evidence is not sufficient and cannot be used to inform practice confidently. However, within the limitations of this review it is suggested that adhesive fixation is preferred in case of short dowel. Dowel width should be as small as possible. A ferrule of 2 mm has to be provided. Composites have proven to be a good core material provided that adequate tooth structure remained for bonding. Dowel should be inserted if endodontically treated tooth is to be used as abutment for removable partial dentures.

Thinking in nursing education. Part II. A teacher's experience.

Science.gov (United States)

Ironside, P M

1999-01-01

Across academia, educators are investigating teaching strategies that facilitate students' abilities to think critically. Because may these strategies require low teacher-student ratios or sustained involvement over time, efforts to implement them are often constrained by diminishing resources for education, faculty reductions, and increasing number of part-time teachers and students. In nursing, the challenges of teaching and learning critical thinking are compounded by the demands of providing care to patients with increasingly acute and complex problems in a wide variety of settings. To meet these challenges, nurse teachers have commonly used a variety of strategies to teach critical thinking (1). For instance, they often provide students with case studies or simulated clinical situations in classroom and laboratory settings (2). At other times, students are taught a process of critical thinking and given structured clinical assignments, such as care plans or care maps, where they apply this process in anticipating the care a particular patient will require. Accompanying students onto clinical units, teachers typically evaluate critical thinking ability by reviewing a student's preparation prior to the experience and discussing it with the student during the course of the experience. The rationales students provide for particular nursing interventions are taken as evidence of their critical thinking ability. While this approach is commonly thought to be effective, the evolving health care system has placed increased emphasis on community nursing (3,4), where it is often difficult to prespecify learning experiences or to anticipate patient care needs. In addition, teachers are often not able to accompany each student to the clinical site. Thus, the traditional strategies for teaching and learning critical thinking common to hospital-based clinical courses are being challenged, transformed, and extended (5). Part II of this article describes findings that suggest

Mammalian Toxicity of Munition Compounds. Phase II. Effects of Multiple Doses. Part III. 2,6-Dinitrotoluene

Science.gov (United States)

1976-07-01

and the neuromuscular effects in these dogs were not due to hypocalcemia . The lowest serum calcium concen- tration in these dogs was 4.2 meq/liter...motor end plate might produce a local hypocalcemia . Such a mechanism is purely speculative. Qualitatively and quantitavely, most of the effects of 2,6...I ýNw,- -MIM I/ MIDWEST RESEARCH INS14ITUTE H0q .3L I LU -_ MAMMALIAN TOXICITY OF MUNITIONS COMPOUlNDSPHASE II: EFFECTS OF MiULTIPLE DOSES C* •PART

Modelo computacional para suporte à decisão em áreas irrigadas. Parte II: testes e aplicação Computer model for decision support in irrigated areas. Part II: tests and application

Directory of Open Access Journals (Sweden)

Paulo A. Ferreira

2006-12-01

Full Text Available Apresentou-se, na Parte I desta pesquisa, o desenvolvimento de um modelo computacional denominado MCID, para suporte à tomada de decisão quanto ao planejamento e manejo de projetos de irrigação e/ou drenagem. Objetivou-se, na Parte II, testar e aplicar o MCID. No teste comparativo com o programa DRAINMOD, espaçamentos entre drenos, obtidos com o MCID, foram ligeiramente maiores ou idênticos. Os espaçamentos advindos com o MCID e o DRAINMOD foram consideravelmente maiores que os obtidos por meio de metodologias tradicionais de dimensionamento de sistemas de drenagem. A produtividade relativa total, YRT, obtida com o MCID foi, em geral, inferior à conseguida com o DRAINMOD, devido a diferenças de metodologia ao se estimar a produtividade da cultura em resposta ao déficit hídrico. Na comparação com o programa CROPWAT, obtiveram-se resultados muito próximos para (YRT e evapotranspiração real. O modelo desenvolvido foi aplicado para as condições do Projeto Jaíba, MG, para culturas perenes e anuais cultivadas em diferentes épocas. Os resultados dos testes e aplicações indicaram a potencialidade do MCID como ferramenta de apoio à decisão em projetos de irrigação e/ou drenagem.Part I of this research presented the development of a decision support model, called MCID, for planning and managing irrigation and/or drainage projects. Part II is aimed at testing and applying MCID. In a comparative test with the DRAINMOD model, drain spacings obtained with MCID were slightly larger or identical. The spacings obtained with MCID and DRAINMOD were considerably larger than those obtained through traditional methodologies of design of drainage systems. The relative crop yield (YRT obtained with MCID was, in general, lower than the one obtained with DRAINMOD due to differences in the estimate of crop response to water deficit. In comparison with CROPWAT, very close results for YRT and for actual evapotranspiration were obtained. The

Impact of monovalent cations on soil structure. Part II. Results of two Swiss soils

Science.gov (United States)

Farahani, Elham; Emami, Hojat; Keller, Thomas

2018-01-01

In this study, we investigated the impact of adding solutions with different potassium and sodium concentrations on dispersible clay, water retention characteristics, air permeability, and soil shrinkage behaviour using two agricultural soils from Switzerland with different clay content but similar organic carbon to clay ratio. Three different solutions (including only Na, only K, and the combination of both) were added to soil samples at three different cation ratio of soil structural stability levels, and the soil samples were incubated for one month. Our findings showed that the amount of readily dispersible clay increased with increasing Na concentrations and with increasing cation ratio of soil structural stability. The treatment with the maximum Na concentration resulted in the highest water retention and in the lowest shrinkage capacity. This was was associated with high amounts of readily dispersible clay. Air permeability generally increased during incubation due to moderate wetting and drying cycles, but the increase was negatively correlated with readily dispersible clay. Readily dispersible clay decreased with increasing K, while readily dispersible clay increased with increasing K in Iranian soil (Part I of our study). This can be attributed to the different clay mineralogy of the studied soils (muscovite in Part I and illite in Part II).

Seismic risk analysis for General Electric Plutonium Facility, Pleasanton, California. Final report, part II

International Nuclear Information System (INIS)

1980-01-01

This report is the second of a two part study addressing the seismic risk or hazard of the special nuclear materials (SNM) facility of the General Electric Vallecitos Nuclear Center at Pleasanton, California. The Part I companion to this report, dated July 31, 1978, presented the seismic hazard at the site that resulted from exposure to earthquakes on the Calaveras, Hayward, San Andreas and, additionally, from smaller unassociated earthquakes that could not be attributed to these specific faults. However, while this study was in progress, certain additional geologic information became available that could be interpreted in terms of the existance of a nearby fault. Although substantial geologic investigations were subsequently deployed, the existance of this postulated fault, called the Verona Fault, remained very controversial. The purpose of the Part II study was to assume the existance of such a capable fault and, under this assumption, to examine the loads that the fault could impose on the SNM facility. This report first reviews the geologic setting with a focus on specifying sufficient geologic parameters to characterize the postulated fault. The report next presents the methodology used to calculate the vibratory ground motion hazard. Because of the complexity of the fault geometry, a slightly different methodology is used here compared to the Part I report. This section ends with the results of the calculation applied to the SNM facility. Finally, the report presents the methodology and results of the rupture hazard calculation

CHILD WELFARE IN CANADA : PART II

OpenAIRE

松本, 眞一; Shinichi, Matsumoto; 桃山学院大学社会学部

2006-01-01

This part study aims to research on the whole aspect of child protection in Canada. And so, this paper consists of five chapters as follows: (1)Canadian history of child protection, (2)definition of child abuse, (3)current situation of child protection in Canada, (4)outline of child protection and treatment, (5)triangular comparison of child protection and prevention in Canada, Australia and England. The first efforts at identifying and combating child abuse occurred in the latter part of the...

The Belle II Experiment

CERN Document Server

Kahn, J

2017-01-01

Set to begin data taking at the end of 2018, the Belle II experiment is the next-generation B-factory experiment hosted at KEK in Tsukuba, Japan. The experiment represents the cumulative effort from the collaboration of experimental and detector physics, computing, and software development. Taking everything learned from the previous Belle experiment, which ran from 1998 to 2010, Belle II aims to probe deeper than ever before into the field of heavy quark physics. By achieving an integrated luminosity of 50 ab−1 and accumulating 50 times more data than the previous experiment across its lifetime, along with a rewritten analysis framework, the Belle II experiment will push the high precision frontier of high energy physics. This paper will give an overview of the key components and development activities that make the Belle II experiment possible.

Radiation protection instruments based on tissue equivalent proportional counters: Part II of an international intercomparison

International Nuclear Information System (INIS)

Alberts, W.G.; Dietz, E.; Guldbakke, S.; Kluge, H.; Schumacher, H.

1988-04-01

This report describes the irradiation conditions and procedures of Part II of an international intercomparison of tissue-equivalent proportional counters used for radiation protection measurements. The irradiations took place in monoenergetic reference neutron fields produced by the research reactor and accelerator facilities of the PTB Braunschweig in the range from thermal neutrons to 14.8 MeV. In addition measurements were performed in 60 Co and D 2 O-moderated 252 Cf radiation fields. Prototype instruments from 7 European groups were investigated. The results of the measurements are summarized and compared with the reference data of the irradiations. (orig.) [de

The prediction of creep damage in Type 347 weld metal: part II creep fatigue tests

International Nuclear Information System (INIS)

Spindler, M.W.

2005-01-01

Calculations of creep damage under conditions of strain control are often carried out using either a time fraction approach or a ductility exhaustion approach. In part I of this paper the rupture strength and creep ductility data for a Type 347 weld metal were fitted to provide the material properties that are used to calculate creep damage. Part II of this paper examines whether the time fraction approach or the ductility exhaustion approach gives the better predictions of creep damage in creep-fatigue tests on the same Type 347 weld metal. In addition, a new creep damage model, which was developed by removing some of the simplifying assumptions that are made in the ductility exhaustion approach, was used. This new creep damage model is a function of the strain rate, stress and temperature and was derived from creep and constant strain rate test data using a reverse modelling technique (see part I of this paper). It is shown that the new creep damage model gives better predictions of creep damage in the creep-fatigue tests than the time fraction and the ductility exhaustion approaches

A comprehensive review and update on the biologic treatment of adult noninfectious uveitis: part II.

Science.gov (United States)

Lee, Kyungmin; Bajwa, Asima; Freitas-Neto, Clovis A; Metzinger, Jamie Lynne; Wentworth, Bailey A; Foster, C Stephen

2014-11-01

Treatment of adult, noninfectious uveitis remains a major challenge for ophthalmologists around the world, especially in regard to recalcitrant cases. It is reported to comprise approximately 10% of preventable blindness in the USA. The cause of uveitis can be idiopathic or associated with infectious and systemic disorders. The era of biologic medical therapies provides new options for patients with otherwise treatment-resistant inflammatory eye disease. This two-part review gives a comprehensive overview of the existing medical treatment options for patients with adult, noninfectious uveitis, as well as important advances for the treatment ocular inflammation. Part I covers classic immunomodulation and latest information on corticosteroid therapy. In part II, emerging therapies are discussed, including biologic response modifiers, experimental treatments and ongoing clinical studies for uveitis. The hazard of chronic corticosteroid use in the treatment of adult, noninfectious uveitis is well documented. Corticosteroid-sparing therapies, which offer a very favorable risk-benefit profile when administered properly, should be substituted. Although nothing is currently approved for on-label use in this indication, many therapies, through either translation or novel basic science research, have the potential to fill the currently exposed gaps.

Norepinephrine metabolism in neuronal cultures is increased by angiotensin II

International Nuclear Information System (INIS)

Sumners, C.; Shalit, S.L.; Kalberg, C.J.; Raizada, M.K.

1987-01-01

In this study the authors have examined the actions of angiotensin II (ANG II) on catecholamine metabolism in neuronal brain cell cultures prepared from the hypothalamus and brain stem. Neuronal cultures prepared from the brains of 1-day-old Sprague-Dawley rats exhibit specific neuronal uptake mechanisms for both norepinephrine (NE) and dopamine (DA), and also monoamine oxidase (MAO) and catechol O-methyltransferase (COMT) activity. Separate neuronal uptake sites for NE and DA were identified by using specific neuronal uptake inhibitors for each amine. In previous studies, they determined that ANG II (10 nM-1 μM) stimulates increased neuronal [ 3 H]NE uptake by acting as specific receptors. They have confirmed these results here and in addition have shown that ANG II has not significant effects on neuronal [ 3 H]DA uptake. These results suggest that the actions of ANG II are restricted to the NE transporter in neuronal cultures. It is possible that ANG II stimulates the intraneuronal metabolism of at least part of the NE that is taken up, because the peptide stimulates MAO activity, an effect mediated by specific ANG II receptors. ANG II had no effect on COMT activity in neuronal cultures. Therefore, the use of neuronal cultures of hypothalamus and brain stem they have determined that ANG II can specifically alter NE metabolism in these areas, while apparently not altering DA metabolism

VATICANO II CONCILIO DOCTRINAL?

Directory of Open Access Journals (Sweden)

Horacio Bojorge

1970-01-01

Full Text Available It is a century since the army of Victor Manuel invaded Rome and put an end to Vatican I. In this article we try to understand Vatican II linking it to the previous circumtances and binding it to its doctrinal and pastoral character. Vatican II omitted many subjects that seemed important, e. g. not giving any dogmatic definitions. Contrasting with the Tridentine and Vatican I, that were mostly doctrinal, Vatican II was pastoral. But it was also doctrinal as were the two previous also pastoral. The Constitution "Dei Verbum" brings forth the intentions that led John XXIII to summon the Council in 5-8-1962. The world looked confused and agitated. What could the Church do?

French RSE-M and RCC-MR code appendices for flaw analysis: Presentation of the fracture parameters calculation-Part II: Cracked plates

International Nuclear Information System (INIS)

Marie, S.; Chapuliot, S.; Kayser, Y.; Lacire, M.H.; Drubay, B.; Barthelet, B.; Le Delliou, P.; Rougier, V.; Naudin, C.; Gilles, P.; Triay, M.

2007-01-01

French nuclear codes include flaw assessment procedures: the RSE-M Code 'Rules for In-service Inspection of Nuclear Power Plant Components' and the RCC-MR code 'Design and Construction rules for mechanical components of FBR nuclear islands and high temperature applications'. An important effort of development of these analytical methods has been made for the last 10 years in the frame of a collaboration between CEA, EDF and AREVA-NP, and in the frame of R and D actions involving CEA and IRSN. These activities have led to a unification of the common methods of the two codes. The calculation of fracture mechanics parameters, and in particular the stress intensity factor K I and the J integral, has been widely developed for industrial configurations. All the developments have been integrated in the 2005 edition of RSE-M and in the 2007 edition of RCC-MR. This series of articles is composed of 5 parts: the first part presents an overview of the methods proposed in the RCC-MR and RSE-M codes. Parts II-IV provide compendia for specific components. The geometries are plates (part II), pipes (part III) and elbows (part IV). Finally, part V presents the validation elements of the methods, with details on the process followed for the development and evaluation of the accuracy of the proposed analytical methods. This second article in the series presents all details for the stress intensity factor and J calculations for cracked plates. General data applicable for all defect geometries are first presented, and then, available defect geometries where compendia for K I and σ ref calculation are provided are given

Digital logic circuit design with ALTERA MAX+PLUS II

International Nuclear Information System (INIS)

Lee, Seung Ho; Park, Yong Su; Park, Gun Jong; Lee, Ju Heon

2006-09-01

This book is composed of five parts. The first part has introduction of ALTERA MAX+PLUS II and graphic editor, text editor, compiler, waveform editor simulator and timing analyzer of it. The second part is about direction of digital logic circuit design with training kit. The third part has grammar and practice of VHDL in ALTERA MAX+PLUS II including example and history of VHDL. The fourth part shows the design example of digital logic circuit by VHDL of ALTERA MAX+PLUS II which lists designs of adder and subtractor, code converter, counter, state machine and LCD module. The last part explains design example of digital logic circuit by graphic editor in ALTERA MAX+PLUS II.

Compósitos de borracha natural ou policloropreno e celulose II: influência do tamanho de partícula Natural rubber or chloroprene rubber and cellulose II composites: influence of particle size

Directory of Open Access Journals (Sweden)

Bruno de A. Napolitano

2004-01-01

Full Text Available O objetivo deste trabalho foi o desenvolvimento de compósitos claros com propriedades de interesse tecnológico utilizando elastômeros com diferentes polaridades. Para que este objetivo fosse atingido, celulose II em pó foi usada como carga, em borracha natural (NR ou policloropreno (CR. A celulose II foi obtida por coagulação da solução de xantato de celulose em meio ácido, sob agitação constante e à temperatura ambiente, constituindo uma nova forma de obtenção deste tipo de carga. Compósitos com 10 phr de celulose II com NR e CR, respectivamente, foram desenvolvidos tendo como variável o tamanho de partícula da carga. As propriedades mecânicas e os aspectos microscópicos dos diferentes compósitos foram avaliados e comparados com aqueles das formulações sem carga. Os resultados permitiram identificar o compósito como o de melhor resultado, influenciado pela polaridade da matriz elastomérica e pelo tamanho de partícula da carga, conseqüência das condições de moagem usadas.The aim of this work was to develop light composites with properties of technological interest by using elastomers of different polarities. This was achieved by employing cellulose II, in the powder form, as filler in natural rubber (NR and chloroprene (CR. Cellulose II was obtained by coagulation of cellulose xanthate solution, in acid medium, under stirring and at room temperature, which represents, to our knowledge, a new way of obtaining this type of filler. Composites with 10phr of cellulose II and NR or CR were prepared having the particle size as variable. The mechanical properties and the microscopic aspect of the different composites were evaluated and compared with compounds without filler. The results indicated best results for the CR composite, influenced by the polarity of the elastomeric matrix and by the particle size, as a consequence of the milling conditions of the filler used.

Hierarchical competition models with the Allee effect II: the case of immigration.

Science.gov (United States)

Assas, Laila; Dennis, Brian; Elaydi, Saber; Kwessi, Eddy; Livadiotis, George

2015-01-01

This is part II of an earlier paper that dealt with hierarchical models with the Allee effect but with no immigration. In this paper, we greatly simplify the proofs in part I and provide a proof of the global dynamics of the non-hyperbolic cases that were previously conjectured. Then, we show how immigration to one of the species or to both would, drastically, change the dynamics of the system. It is shown that if the level of immigration to one or to both species is above a specified level, then there will be no extinction region where both species go to extinction.

EL español andino. II parte

Directory of Open Access Journals (Sweden)

Rubén Arboleda Toro

2002-01-01

Full Text Available En el número 13 de esta revista (nov. del 2000 se publicó una primera parte del estudio sobre el español andino. Presentamos ahora una segunda parte que comprende aspectos histórico-geográficos de Nariño y Putumayo andinos, región de Colombia donde se habla esa variedad, y una descripción general de su realidad lingüística. Esperamos que sean objeto de otra publicación la descripción de los rasgos dialectales del español andino, parte nuclear del trabajo, y la presentación de la metodología y el corpus. En esto nos encontramos trabajando. Incluimos no obstante un inventario de rasgos más amplio que el presentado en la primera parte. Pero por ahora se trata de eso, de un inventario ilustrativo, no del análisis en el que estamos empeñados, en el marco del contacto de lenguas, el cambio lingüístico y la relación entre la norma y las posibilidades del sistema. Para contextualizar esta segunda parte, incluimos, a manera de introducción, un resumen de la primera.

The Search for Another Earth–Part II

Indian Academy of Sciences (India)

Permanent link: https://www.ias.ac.in/article/fulltext/reso/021/10/0899-0910. Keywords. Exoplanets, earth, super-earth, diamond planet, neptune, habitability, extra-terrestrial life. Abstract. In the first part, we discussed the various methods for thedetection of planets outside the solar system known as theexoplanets. In this part ...

Reproduce and die! Why aging? Part II

NARCIS (Netherlands)

Schuiling, GA

Whilst in part I of this diptych on aging the question why aging exists at all is discussed; this part deals with the question which mechanisms underly aging and, ultimately, dying. It appears that aging is not just an active process as such - although all kinds of internal (e.g., oxigen-free

Getting to the Source: a Survey of Quantitative Data Sources Available to the Everyday Librarian: Part II: Data Sources from Specific Library Applications

Directory of Open Access Journals (Sweden)

Lisa Goddard

2007-03-01

Full Text Available This is the second part of a two-part article that provides a survey of data sources which are likely to be immediately available to the typical practitioner who wishes to engage in statistical analysis of collections and services within his or her own library. Part I outlines the data elements which can be extracted from web server logs, and discusses web log analysis tools. Part II looks at logs, reports, and data sources from proxy servers, resource vendors, link resolvers, federated search engines, institutional repositories, electronic reference services, and the integrated library system.

Impacts of Realistic Urban Heating. Part II: Air Quality and City Breathability

Science.gov (United States)

Nazarian, Negin; Martilli, Alberto; Norford, Leslie; Kleissl, Jan

2018-03-01

Urban morphology and inter-building shadowing result in a non-uniform distribution of surface heating in urban areas, which can significantly modify the urban flow and thermal field. In Part I, we found that in an idealized three-dimensional urban array, the spatial distribution of the thermal field is correlated with the orientation of surface heating with respect to the wind direction (i.e. leeward or windward heating), while the dispersion field changes more strongly with the vertical temperature gradient in the street canyon. Here, we evaluate these results more closely and translate them into metrics of "city breathability," with large-eddy simulations coupled with an urban energy-balance model employed for this purpose. First, we quantify breathability by, (i) calculating the pollutant concentration at the pedestrian level (horizontal plane at z≈ 1.5 -2 m) and averaged over the canopy, and (ii) examining the air exchange rate at the horizontal and vertical ventilating faces of the canyon, such that the in-canopy pollutant advection is distinguished from the vertical removal of pollution. Next, we quantify the change in breathability metrics as a function of previously defined buoyancy parameters, horizontal and vertical Richardson numbers (Ri_h and Ri_v , respectively), which characterize realistic surface heating. We find that, unlike the analysis of airflow and thermal fields, consideration of the realistic heating distribution is not crucial in the analysis of city breathability, as the pollutant concentration is mainly correlated with the vertical temperature gradient (Ri_v ) as opposed to the horizontal (Ri_h ) or bulk (Ri_b ) thermal forcing. Additionally, we observe that, due to the formation of the primary vortex, the air exchange rate at the roof level (the horizontal ventilating faces of the building canyon) is dominated by the mean flow. Lastly, since Ri_h and Ri_v depend on the meteorological factors (ambient air temperature, wind speed, and

Schinus terebinthifolius countercurrent chromatography (Part III): Method transfer from small countercurrent chromatography column to preparative centrifugal partition chromatography ones as a part of method development.

Science.gov (United States)

das Neves Costa, Fernanda; Hubert, Jane; Borie, Nicolas; Kotland, Alexis; Hewitson, Peter; Ignatova, Svetlana; Renault, Jean-Hugues

2017-03-03

Countercurrent chromatography (CCC) and centrifugal partition chromatography (CPC) are support free liquid-liquid chromatography techniques sharing the same basic principles and features. Method transfer has previously been demonstrated for both techniques but never from one to another. This study aimed to show such a feasibility using fractionation of Schinus terebinthifolius berries dichloromethane extract as a case study. Heptane - ethyl acetate - methanol -water (6:1:6:1, v/v/v/v) was used as solvent system with masticadienonic and 3β-masticadienolic acids as target compounds. The optimized separation methodology previously described in Part I and II, was scaled up from an analytical hydrodynamic CCC column (17.4mL) to preparative hydrostatic CPC instruments (250mL and 303mL) as a part of method development. Flow-rate and sample loading were further optimized on CPC. Mobile phase linear velocity is suggested as a transfer invariant parameter if the CPC column contains sufficient number of partition cells. Copyright © 2017 Elsevier B.V. All rights reserved.

Complexometric determination, Part II: Complexometric determination of Cu2+-ions

Directory of Open Access Journals (Sweden)

Rajković Miloš B.

2002-01-01

Full Text Available A copper-selective electrode of the coated wire type based on sulphidized copper wire was applied successfully for determining Cu(II ions by complexometric titration with the disodium salt of EDTA (complexon III. By the formation of internal complex compounds with the Cu(II ion, the copper concentration in the solution decreases, and all this is followed by a change of potential of the indicator system Cu-DWISE (or Cu-EDWISE/SCE. At the terminal point of titration, when all the Cu(II ions are already utilized for the formation of the complex with EDTA, there occurs a steep rise of potential, thus enabling us, through the first or second derivative to note the quantity of copper that is present in the solution. Copper-selective electrode showed a responsivity towards titration with EDTA as a complexing agent, with the absence of "fatigue" due to a great number of repeated measurings. Errors occurring during quantitative measurements were more a characteristic of the overall procedure which involve, because of the impossibility of the complete absence of subjectivity, a constant error, and the reproducibility of the results confirmed this fact. The disodium salt of EDTA appeared as a very efficient titrant in all titrations and with various concentrations ot Cu(II ions in the solution, with somewhat weaker response at lower concentrations in the solution.

A Conversation with William A. Fowler Part II

Science.gov (United States)

Greenberg, John

2005-06-01

Physicist William A.Fowler initiated an experimental program in nuclear astrophysics after World War II. He recalls here the Steady State versus Big Bang controversy and his celebrated collaboration with Fred Hoyle and Geoffrey and Margaret Burbidge on nucleosynthesis in stars. He also comments on the shift away from nuclear physics in universities to large accelerators and national laboratories.

Interview-Based Qualitative Research in Emergency Care Part II: Data Collection, Analysis and Results Reporting

Science.gov (United States)

Ranney, Megan L.; Meisel, Zachary; Choo, Esther K.; Garro, Aris; Sasson, Comilla; Morrow, Kathleen

2015-01-01

Qualitative methods are increasingly being used in emergency care research. Rigorous qualitative methods can play a critical role in advancing the emergency care research agenda by allowing investigators to generate hypotheses, gain an in-depth understanding of health problems or specific populations, create expert consensus, and develop new intervention and dissemination strategies. In Part I of this two-article series, we provided an introduction to general principles of applied qualitative health research and examples of its common use in emergency care research, describing study designs and data collection methods most relevant to our field (observation, individual interviews, and focus groups). Here in Part II of this series, we outline the specific steps necessary to conduct a valid and reliable qualitative research project, with a focus on interview-based studies. These elements include building the research team, preparing data collection guides, defining and obtaining an adequate sample, collecting and organizing qualitative data, and coding and analyzing the data. We also discuss potential ethical considerations unique to qualitative research as it relates to emergency care research. PMID:26284572

Interview-based Qualitative Research in Emergency Care Part II: Data Collection, Analysis and Results Reporting.

Science.gov (United States)

Ranney, Megan L; Meisel, Zachary F; Choo, Esther K; Garro, Aris C; Sasson, Comilla; Morrow Guthrie, Kate

2015-09-01

Qualitative methods are increasingly being used in emergency care research. Rigorous qualitative methods can play a critical role in advancing the emergency care research agenda by allowing investigators to generate hypotheses, gain an in-depth understanding of health problems or specific populations, create expert consensus, and develop new intervention and dissemination strategies. In Part I of this two-article series, we provided an introduction to general principles of applied qualitative health research and examples of its common use in emergency care research, describing study designs and data collection methods most relevant to our field (observation, individual interviews, and focus groups). Here in Part II of this series, we outline the specific steps necessary to conduct a valid and reliable qualitative research project, with a focus on interview-based studies. These elements include building the research team, preparing data collection guides, defining and obtaining an adequate sample, collecting and organizing qualitative data, and coding and analyzing the data. We also discuss potential ethical considerations unique to qualitative research as it relates to emergency care research. © 2015 by the Society for Academic Emergency Medicine.

Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases. Part 3: Michael addition reactions and miscellaneous transformations.

Science.gov (United States)

Aceña, José Luis; Sorochinsky, Alexander E; Soloshonok, Vadim

2014-09-01

The major goal of this review is a critical discussion of the literature data on asymmetric synthesis of α-amino acids via Michael addition reactions involving Ni(II)-complexes of amino acids. The material covered is divided into two conceptually different groups dealing with applications of: (a) Ni(II)-complexes of glycine as C-nucleophiles and (b) Ni(II)-complexes of dehydroalanine as Michael acceptors. The first group is significantly larger and consequently subdivided into four chapters based on the source of stereocontrolling element. Thus, a chiral auxiliary can be used as a part of nucleophilic glycine Ni(II) complex, Michael acceptor or both, leading to the conditions of matching vs. mismatching stereochemical preferences. The particular focus of the review is made on the practical aspects of the methodology under discussion and mechanistic considerations.

A study of drying and cleaning methods used in preparation for fluorescent penetrant inspection - Part II

International Nuclear Information System (INIS)

Brasche, L.; Lopez, R.; Larson, B.

2003-01-01

Fluorescent penetrant inspection is the most widely used method for aerospace components such as critical rotating components of gas turbine engines. Successful use of FPI begins with a clean and dry part, followed by a carefully controlled and applied FPI process, and conscientious inspection by well trained personnel. A variety of cleaning methods are in use for cleaning of titanium and nickel parts with selection based on the soils or contamination to be removed. Cleaning methods may include chemical or mechanical methods with sixteen different types studied as part of this program. Several options also exist for use in drying parts prior to FPI. Samples were generated and exposed to a range of conditions to study the effect of both drying and cleaning methods on the flaw response of FPI. Low cycle fatigue (LCF) cracks were generated in approximately 40 nickel and 40 titanium samples for evaluation of the various cleaning methods. Baseline measurements were made for each of the samples using a photometer to measure sample brightness and a UVA videomicroscope to capture digital images of the FPI indications. Samples were exposed to various contaminants, cleaned and inspected. Brightness measurements and digital images were also taken to compare to the baseline data. A comparison of oven drying to flash dry in preparation for FPI has been completed and will be reported in Part I. Comparison of the effectiveness of various cleaning methods for the contaminants will be presented in Part II. The cleaning and drying studies were completed in cooperation with Delta Airlines using cleaning, drying and FPI processes typical of engine overhaul processes and equipment. The work was completed as part of the Engine Titanium Consortium and included investigators from Honeywell, General Electric, Pratt and Whitney, and Rolls Royce

Instructional climates in preschool children who are at-risk. Part II: perceived physical competence.

Science.gov (United States)

Robinson, Leah E; Rudisill, Mary E; Goodway, Jacqueline D

2009-09-01

In Part II of this study, we examined the effect of two 9-week instructional climates (low-autonomy [LA] and mastery motivational climate [MMC]) on perceived physical competence (PPC) in preschoolers (N = 117). Participants were randomly assigned to an LA, MMC, or comparison group. PPC was assessed by a pretest, posttest, and retention test with the Pictorial Scale of Perceived Competence and Social Acceptance. A significant Treatment x Time interaction (p < .001) was present, supporting that MMC participants reported significantly higher PPC scores over time, while no positive changes were present in LA and comparison participants. The results show that an MMC leads to psychological benefits related to achievement motivation. These findings should encourage early childhood educators to consider the effect of instructional climates on children's self-perception.

Phase II trial of veliparib in patients with previously treated BRCA-mutated pancreas ductal adenocarcinoma.

Science.gov (United States)

Lowery, Maeve A; Kelsen, David P; Capanu, Marinela; Smith, Sloane C; Lee, Jonathan W; Stadler, Zsofia K; Moore, Malcolm J; Kindler, Hedy L; Golan, Talia; Segal, Amiel; Maynard, Hannah; Hollywood, Ellen; Moynahan, MaryEllen; Salo-Mullen, Erin E; Do, Richard Kinh Gian; Chen, Alice P; Yu, Kenneth H; Tang, Laura H; O'Reilly, Eileen M

2018-01-01

BRCA-associated cancers have increased sensitivity to poly(ADP-ribose) polymerase inhibitors (PARPis). This single arm, non-randomised, multicentre phase II trial evaluated the response rate of veliparib in patients with previously treated BRCA1/2- or PALB2-mutant pancreatic adenocarcinoma (PDAC). Patients with stage III/IV PDAC and known germline BRCA1/2 or PALB2 mutation, 1-2 lines of treatment, Eastern Cooperative Oncology Group 0-2, were enrolled. Veliparib was dosed at a volume of 300 mg twice-daily (N = 3), then 400 mg twice-daily (N = 15) days 1-28. The primary end-point was to determine the response rate of veliparib; secondary end-points included progression-free survival (PFS), duration of response, overall survival (OS) and safety. Sixteen patients were enrolled; male N = 8 (50%). Median age was 52 years (range 43-77). Five (31%) had a BRCA1 and 11 (69%) had a BRCA2 mutation. Fourteen (88%) patients had received prior platinum-based therapy. No confirmed partial responses (PRs) were seen: one (6%) unconfirmed PR was observed at 4 months with disease progression (PD) at 6 months; four (25%) had stable disease (SD), whereas 11 (69%) had PD as best response including one with clinical PD. Median PFS was 1.7 months (95% confidence interval [CI] 1.57-1.83) and median OS was 3.1 months (95% CI 1.9-4.1). Six (38%) patients had grade III toxicity, including fatigue (N = 3), haematology (N = 2) and nausea (N = 1). Veliparib was well tolerated, but no confirmed response was observed although four (25%) patients remained on study with SD for ≥ 4 months. Additional strategies in this population are needed, and ongoing trials are evaluating PARPis combined with chemotherapy (NCT01585805) and as a maintenance strategy (NCT02184195). Copyright © 2017 Elsevier Ltd. All rights reserved.

Short-term effects of air pollution on respiratory morbidity at Rio de Janeiro--Part II: health assessment.

Science.gov (United States)

Sousa, S I V; Pires, J C M; Martins, E M; Fortes, J D N; Alvim-Ferraz, M C M; Martins, F G

2012-08-01

The effects of air pollution on health have been studied worldwide. Given that air pollution triggers oxidative stress and inflammation, it is plausible that high levels of air pollutants cause higher number of hospitalisations. This study aimed to assess the impact of air pollution on the emergency hospitalisation for respiratory disease in Rio de Janeiro, Brazil. The study was divided in two parts: Part I specifically addressing the air pollution assessment and Part II addressing the health assessment. Accordingly, this Part II aimed to estimate the association between the concentrations of PM₁₀, SO₂ and CO observed in Rio de Janeiro and the number of emergency hospitalisations at a central hospital due to respiratory diseases. The pollutant concentrations were measured at two different sites in Rio de Janeiro, but the excess relative risks were calculated based on the concentrations observed at one of the sites, where limits were generally exceeded more frequently, between September 2000 and December 2005. A time series analysis was performed using the number of hospitalisations, divided in three categories (children until 1 year old, children aged between 1 and 5 years old and elderly with 65 years old or more) as independent variable, the concentrations of pollutants as dependent variables and temperature, relative humidity, long term trend, and seasonality as confounders. Data were analysed using generalised additive models with smoothing for some of the dependent variables. Results showed an excess risk of hospitalisation for respiratory disease higher than 2% per 10 μg m⁻³ increase in PM₁₀ concentrations for children under 5 years old, of 2% per 10 μg m⁻³ increase in SO₂ for elderly above 65 years old and around 0.1% per 10 μg m⁻³ increase in CO for children under 1 year and elderly. Other studies have found associations that are in agreement with the results achieved in this study. The study suggests that the ambient levels of air

Pedagogical progeniture or tactical translation? George Fordyce's additions and modifications to William Cullen's philosophical chemistry--Part II.

Science.gov (United States)

Taylor, Georgette

2014-08-01

This paper compares the affinity theories and the associated affinity diagrams of William Cullen (1710-1790) and George Fordyce (1736-1802), exploring in particular one episode that took place during the brief hiatus between Fordyce's student years at Edinburgh University and the start of his own pedagogical career in London. This investigation complements that contained in Part I of this paper, which compared the chemistry courses given by Cullen and Fordyce, demonstrating that the knowledge originally imparted to Fordyce by Cullen in his Edinburgh lectures was augmented and translated by Fordyce for his own pedagogical purposes. Part II offers greater insight into the flow of knowledge between Fordyce and Cullen. Their correspondence suggests that the relationship between master and student transmuted into something more complicated after Fordyce left Edinburgh, while the model of knowledge transmission between the two can be seen to be more collaborative than might be expected.

THE SPECTRUM AND TERM ANALYSIS OF V II

International Nuclear Information System (INIS)

Thorne, A. P.; Pickering, J. C.; Semeniuk, J. I.

2013-01-01

The spectrum and extended term analysis of V II are presented. Fourier transform spectrometry was used to record high resolution spectra of singly ionized vanadium in the region 1492-5800 Å (67020-17260 cm –1 ) with vanadium-neon and vanadium-argon hollow cathode lamps as sources. The wavenumber uncertainty for the center of gravity of the strongest lines is typically 0.002 cm –1 , an improvement of an order of magnitude over previous measurements. Most of the lines exhibit partly resolved hyperfine structure. The V II energy levels in the 1985 compilation of Sugar and Corliss have been confirmed and revised, with the exception of the high-lying 4f levels and eight of the lower levels. Thirty-nine of the additional eighty-five high levels published by Iglesias et al. have also been confirmed and revised, and three of their missing levels have been found. The energy uncertainty of the revised levels has been reduced by about an order of magnitude. In total, 176 even levels and 233 odd levels are presented. Wavenumbers and classifications are given for 1242 V II lines

14 CFR 121.406 - Credit for previous CRM/DRM training.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Credit for previous CRM/DRM training. 121... previous CRM/DRM training. (a) For flightcrew members, the Administrator may credit CRM training received before March 19, 1998 toward all or part of the initial ground CRM training required by § 121.419. (b...

The removal of toxic metals from liquid effluents by ion exchange resins. Part VI: Manganese(II/H+/Lewatit K2621

Directory of Open Access Journals (Sweden)

Francisco J. Alguacil

2018-05-01

Full Text Available In this sixth part of the series, Manganese(II was removed from aqueous solutions by the cationic exchange resin Lewatit K2621. The investigation was performed under various experimental conditions such as the stirring speed associated with the system, aqueous pH, temperature, resin dosage and the ionic strength of the solution. The performance of the resin against the loading of metals from metal-binary solutions as well as the removal of Manganese(II from the solutions using multiwalled carbon nanotubes and functionalized (carboxylic groups multiwalled carbon nanotubes, were also investigated. Experimental results fit well with the pseudo-first kinetic order model, whereas fit of the data show that at 20 °C the process responded well to the diffusion controlled model, and that at 60 °C, the system is controlled by the moving boundary model. Adsorption data is better related to the Freundlich isotherm. Elution of the Manganese(II loaded onto the resin was investigated using acidic (H2SO4 or HCl solutions.

Zn(II, Mn(II and Sr(II Behavior in a Natural Carbonate Reservoir System. Part I: Impact of Salinity, Initial pH and Initial Zn(II Concentration in Atmospheric Conditions

Directory of Open Access Journals (Sweden)

Auffray B.

2016-07-01

Full Text Available The sorption of inorganic elements on carbonate minerals is well known in strictly controlled conditions which limit the impact of other phenomena such as dissolution and/or precipitation. In this study, we evidence the behavior of Zn(II (initially in solution and two trace elements, Mn(II and Sr(II (released by carbonate dissolution in the context of a leakage from a CO2 storage site. The initial pH chosen are either equal to the pH of the water-CO2 equilibrium (~ 2.98 or equal to the pH of the water-CO2-calcite system (~ 4.8 in CO2 storage conditions. From this initial influx of liquid, saturated or not with respect to calcite, the batch experiments evolve freely to their equilibrium, as it would occur in a natural context after a perturbation. The batch experiments are carried out on two natural carbonates (from Lavoux and St-Emilion with PCO2 = 10−3.5 bar, with different initial conditions ([Zn(II]i from 10−4 to 10−6 M, either with pure water or 100 g/L NaCl brine. The equilibrium regarding calcite dissolution is confirmed in all experiments, while the zinc sorption evidenced does not always correspond to the two-step mechanism described in the literature. A preferential sorption of about 10% of the concentration is evidenced for Mn(II in aqueous experiments, while Sr(II is more sorbed in saline conditions. This study also shows that this preferential sorption, depending on the salinity, is independent of the natural carbonate considered. Then, the simulations carried out with PHREEQC show that experiments and simulations match well concerning the equilibrium of dissolution and the sole zinc sorption, with log KZn(II ~ 2 in pure water and close to 4 in high salinity conditions. When the simulations were possible, the log K values for Mn(II and Sr(II were much different from those in the literature obtained by sorption in controlled conditions. It is shown that a new conceptual model regarding multiple Trace Elements (TE sorption is

Ni(II) and Cu(II) binding with a 14-aminoacid sequence of Cap43 protein, TRSRSHTSEGTRSR.

Science.gov (United States)

Zoroddu, M A; Kowalik-Jankowska, T; Kozlowski, H; Salnikow, K; Costa, M

2001-03-01

The tetradecapeptide containing the 10 aminoacid repeated sequence on the C-terminus of the Ni(II)-induced Cap43 protein, was analyzed for Ni(II) and Cu(II) binding. A combined pH-metric and spectroscopic UV-VIS, EPR, CD and NMR study of Ni(II) and Cu(II) binding to the blocked CH3CO-Thr-Arg-Ser-Arg-Ser-His-Thr-Ser-Glu-Gly-Thr-Arg-Ser-Arg-NH2 (Ac-TRSRSHTSEGTRSR-Am) peptide, modeling a part of the C-terminal sequence of the Cap43 protein, revealed the formation of octahedral complexes involving imidazole nitrogen of histidine, at pH 5.5 and pH 7 for Cu(II) and Ni(II), respectively; a major square planar 4N-Ni(II) complex (about 100% at pH 9, log K* = -28.16) involving imidazole nitrogen of histidine and three deprotonated amide nitrogens of the backbone of the peptide was revealed; a 3N-Cu(II) complex (maximum about 70% at pH 7, log K*=-13.91) and a series of 4N-Cu(II) complexes starting at pH 5.5 (maximum about 90% at pH 8.7, log K* = -21.39 for CuH(-3)L), were revealed. This work supports the existence of a metal binding site at the COOH-terminal part of the Cap43 peptide.

Engineering data of seamate:II, 2

International Nuclear Information System (INIS)

Tanaka, Susumu; Okada, Sohei; Ito, Masayuki; Kusama, Yasuo; Yoshida, Kenzo; Nakase, Yoshiaki.

1981-09-01

SEAMATE-II (Simulated Environmental Apparatus for Material Testing) was constructed in order to establish methodologies for the test of electrical cables under the conditions of postulated LOCA including radiation, and to provide the engineering data for designing the qualification testing facility. A part of engineering data have been previously reported on rapid heating of the inside of the pressure vessel with its outlet valve closed. The engineering data reported here are as follows, 1) controllability of the control devices at rapid heating, 2) comparison of the temperature control systems based on temperature detection, pressure detection and temperature converted from detected pressure, 3) controllability of the automatic control system during rapid heating and rapid cooling, 4) quantities of steam and cooling water required for the automatic control. (author)

An updated Type II supernova Hubble diagram

Science.gov (United States)

Gall, E. E. E.; Kotak, R.; Leibundgut, B.; Taubenberger, S.; Hillebrandt, W.; Kromer, M.; Burgett, W. S.; Chambers, K.; Flewelling, H.; Huber, M. E.; Kaiser, N.; Kudritzki, R. P.; Magnier, E. A.; Metcalfe, N.; Smith, K.; Tonry, J. L.; Wainscoat, R. J.; Waters, C.

2018-03-01

We present photometry and spectroscopy of nine Type II-P/L supernovae (SNe) with redshifts in the 0.045 ≲ z ≲ 0.335 range, with a view to re-examining their utility as distance indicators. Specifically, we apply the expanding photosphere method (EPM) and the standardized candle method (SCM) to each target, and find that both methods yield distances that are in reasonable agreement with each other. The current record-holder for the highest-redshift spectroscopically confirmed supernova (SN) II-P is PS1-13bni (z = 0.335-0.012+0.009), and illustrates the promise of Type II SNe as cosmological tools. We updated existing EPM and SCM Hubble diagrams by adding our sample to those previously published. Within the context of Type II SN distance measuring techniques, we investigated two related questions. First, we explored the possibility of utilising spectral lines other than the traditionally used Fe IIλ5169 to infer the photospheric velocity of SN ejecta. Using local well-observed objects, we derive an epoch-dependent relation between the strong Balmer line and Fe IIλ5169 velocities that is applicable 30 to 40 days post-explosion. Motivated in part by the continuum of key observables such as rise time and decline rates exhibited from II-P to II-L SNe, we assessed the possibility of using Hubble-flow Type II-L SNe as distance indicators. These yield similar distances as the Type II-P SNe. Although these initial results are encouraging, a significantly larger sample of SNe II-L would be required to draw definitive conclusions. Tables A.1, A.3, A.5, A.7, A.9, A.11, A.13, A.15 and A.17 are also available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/611/A25

Critical thinking and accuracy of nurses' diagnoses. Part II: application of cognitive skills and guidelines for self-development Pensamiento crítico y precisión de los diagnósticos de enfermería. II Parte: aplicación de habilidades cognitivas y guia para el autodesarrollo Pensamento crítico e acurácia dos diagnósticos de enfermagem. Parte II: aplicação de habilidades cognitivas e guia para o auto-desenvolvimento

Directory of Open Access Journals (Sweden)

Margaret Lunney

2003-09-01

Full Text Available Part I of this article, the author explained the difficulties of achieving accuracy of nurses' diagnoses, the relevance of critical thinking to the achievement of accuracy, and newer views of critical thinking. In Part II, the critical thinking dimensions identified as important for nursing practice are applied in the diagnostic process using a case study of a 16 year old girl with type 1 diabetes. Application of seven cognitive skills and ten habits of mind illustrate the importance of using critical thinking for accuracy of nurses' diagnoses. Ten strategies are proposed for self-development of critical thinking abilities.En la I Parte del artículo, el autor explicó las dificultades para alcanzar la precisión de los diagnósticos de enfermería, la relevancia del pensamiento crítico en el logro de esa precisión y las nuevas perspectivas de ese pensamiento. En la II Parte las dimensiones del pensamiento crítico, consideradas como importantes para la práctica de enfermería, son aplicadas en el estudio de caso de una joven de 16 años con Diabetes de tipo 1. La aplicación de las siete habilidades cognitivas y de las diez formas de pensar, ilustra la importancia del uso del pensamiento crítico para la precisión de los diagnósticos de enfermería. Se proponen diez estratégias para el auto-desarrollo de habilidades volcadas al pensamiento crítico.Na Parte I deste artigo, o autor explicou as dificuldades em alcançar a acurácia dos diagnósticos de enfermagem, a relevância do pensamento crítico no alcance dessa acurácia e as mais novas perspectivas desse pensamento. Na Parte II, as dimensões do pensamento crítico identificadas como importantes para a prática de enfermagem são aplicadas em um estudo de caso de uma menina de 16 anos com Diabetes do tipo 1. A aplicação das sete habilidades cognitivas e das dez formas de pensar ilustram a importância do uso do pensamento crítico para a acurácia dos diagnósticos de enfermagem

Cubby : Multiscreen Desktop VR Part II

NARCIS (Netherlands)

Gribnau, M.W.; Djajadiningrat, J.P.

2000-01-01

In this second part of our 'Cubby: Multiscreen Desktop VR' trilogy, we will introduce you to the art of creating a driver to read an Origin Instruments Dynasight input device. With the Dynasight, the position of the head of the user is established so that Cubby can display the correct images on its

PACE. A Program for Acquiring Competence in Entrepreneurship. Part II: Becoming an Entrepreneur. Unit G: Resources for Managerial Assistance. Research and Development Series No. 194 B-7.

Science.gov (United States)

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

This three-part curriculum for entrepreneurship education is primarily for postsecondary level, including four-year colleges and adult education, but it can be adapted for special groups or vocational teacher education. The emphasis of the seven instructional units in Part II is establishing business. Unit G focuses on obtaining managerial…

Outer Sphere Adsorption of Pb(II)EDTA on Goethite

Energy Technology Data Exchange (ETDEWEB)

Bargar, John R

1999-07-16

FTIR and EXAFS spectroscopic measurements were performed on Pb(II)EDTA adsorbed on goethite as functions of pH (4-6), Pb(II)EDTA concentration (0.11 {micro}M - 72 {micro}M), and ionic strength (16 {micro}M - 0.5M). FTIR measurements show no evidence for carboxylate-Fe(III) bonding or protonation of EDTA at Pb:EDTA = 1:1. Both FTIR and EXAFS measurements suggest that EDTA acts as a hexadentate ligand, with all four of its carboxylate and both amine groups bonded to Pb(II). No evidence was observed for inner-sphere Pb(II)-goethite bonding at Pb:EDTA = 1:1. Hence, the adsorbed complexes should have composition Pb(II)EDTA{sup 2{minus}}. Since substantial uptake of PbEDTA(II){sup 2{minus}} occurred in the samples, we infer that Pb(II)EDTA{sup 2{minus}} adsorbed as outer-sphere complexes and/or as complexes that lose part of their solvation shells and hydrogen bond directly to goethite surface sites. We propose the term ''hydration-sphere'' for the latter type of complexes because they should occupy space in the primary hydration spheres of goethite surface functional groups, and to distinguish this mode of sorption from common structural definitions of inner- and outer-sphere complexes. The similarity of Pb(II) uptake isotherms to those of other divalent metal ions complexed by EDTA suggests that they too adsorb by these mechanisms. The lack of evidence for inner-sphere EDTA-Fe(III) bonding suggests that previously proposed metal-ligand - promoted dissolution mechanisms should be modified, specifically to account for the presence of outer-sphere precursor species.

Procedimiento para diseñar el muestreo eólico en una región promisoria. Parte II.Implementación y aplicación; Procedure to design sampling of the wind speed in a promissory region. Part II. Implementation and application

Directory of Open Access Journals (Sweden)

Eduardo Terrero Matos

2015-06-01

Full Text Available En la Parte I de este artículo fue establecido el algoritmo general de un procedimiento para el diseño del muestreo de la velocidad del viento cuyos resultados tengan la capacidad de minimizar el error probable medio durante una estimación del comportamiento espacio-temporal de la velocidad del viento. En la Parte II se describe el algoritmo de selección de puntos de muestreo y el algoritmo para el cálculo del error probable de estimación. El procedimiento para diseñarlas redes de muestreo eólico es implementado en una aplicación informática que facilita la aplicación del procedimiento a la selección de los puntos donde se ubicarán las torres anemométricas en una región promisoria del municipio Moa en la Provincia Holguín, Cuba. Los resultados obtenidos son comparados con el diseño obtenido en el año 2007 por la Empresa de Ingeniería y Proyectos de Electricidad del Ministerio de Energía y Minas de la República de Cuba.In Part I of this article was established the general algorithmof a procedure for the sampling design of the wind speed and the results have the ability to minimize the average probable error for an estimate of the conduct spatiotemporal wind speed. In Part II the selection algorithm of sampling points and the algorithm for calculating the probable error estimation is described. The procedure for the samplingdesign is implemented in an computer software that facilitates the application from the procedure to the selection of the points where theanemometer towers will be located in a promissory region of the municipality Moa in the province Holguín, Cuba. The results are compared with the design obtained in 2007 by the Empresa de Ingeniería y Proyectos de Electricidad of the Ministry of Energy and Mines of the Republic of Cuba.

A case study of packaging waste collection systems in Portugal - Part II: Environmental and economic analysis.

Science.gov (United States)

Pires, Ana; Sargedas, João; Miguel, Mécia; Pina, Joaquim; Martinho, Graça

2017-03-01

An understanding of the environmental impacts and costs related to waste collection is needed to ensure that existing waste collection schemes are the most appropriate with regard to both environment and cost. This paper is Part II of a three-part study of a mixed packaging waste collection system (curbside plus bring collection). Here, the mixed collection system is compared to an exclusive curbside system and an exclusive bring system. The scenarios were assessed using life cycle assessment and an assessment of costs to the waste management company. The analysis focuses on the collection itself so as to be relevant to waste managers and decision-makers who are involved only in this step of the packaging life cycle. The results show that the bring system has lower environmental impacts and lower economic costs, and is capable of reducing the environmental impacts of the mixed system. However, a sensitivity analysis shows that these results could differ if the curbside collection were to be optimized. From economic and environmental perspectives, the mixed system has few advantages. Copyright © 2016 Elsevier Ltd. All rights reserved.

Erlotinib-induced rash spares previously irradiated skin

International Nuclear Information System (INIS)

Lips, Irene M.; Vonk, Ernest J.A.; Koster, Mariska E.Y.; Houwing, Ronald H.

2011-01-01

Erlotinib is an epidermal growth factor receptor inhibitor prescribed to patients with locally advanced or metastasized non-small cell lung carcinoma after failure of at least one earlier chemotherapy treatment. Approximately 75% of the patients treated with erlotinib develop acneiform skin rashes. A patient treated with erlotinib 3 months after finishing concomitant treatment with chemotherapy and radiotherapy for non-small cell lung cancer is presented. Unexpectedly, the part of the skin that had been included in his previously radiotherapy field was completely spared from the erlotinib-induced acneiform skin rash. The exact mechanism of erlotinib-induced rash sparing in previously irradiated skin is unclear. The underlying mechanism of this phenomenon needs to be explored further, because the number of patients being treated with a combination of both therapeutic modalities is increasing. The therapeutic effect of erlotinib in the area of the previously irradiated lesion should be assessed. (orig.)

Unraveling uranium induced oxidative stress related responses in Arabidopsis thaliana seedlings. Part II: responses in the leaves and general conclusions.

Science.gov (United States)

Vanhoudt, Nathalie; Cuypers, Ann; Horemans, Nele; Remans, Tony; Opdenakker, Kelly; Smeets, Karen; Bello, Daniel Martinez; Havaux, Michel; Wannijn, Jean; Van Hees, May; Vangronsveld, Jaco; Vandenhove, Hildegarde

2011-06-01

The cellular redox balance seems an important modulator under heavy metal stress. While for other heavy metals these processes are well studied, oxidative stress related responses are also known to be triggered under uranium stress but information remains limited. This study aimed to further unravel the mechanisms by which plants respond to uranium stress. Seventeen-day-old Arabidopsis thaliana seedlings, grown on a modified Hoagland solution under controlled conditions, were exposed to 0, 0.1, 1, 10 and 100 μM uranium for 1, 3 and 7 days. While in Part I of this study oxidative stress related responses in the roots were discussed, this second Part II discusses oxidative stress related responses in the leaves and general conclusions drawn from the results of the roots and the leaves will be presented. As several responses were already visible following 1 day exposure, when uranium concentrations in the leaves were negligible, a root-to-shoot signaling system was suggested in which plastids could be important sensing sites. While lipid peroxidation, based on the amount of thiobarbituric acid reactive compounds, was observed after exposure to 100 μM uranium, affecting membrane structure and function, a transient concentration dependent response pattern was visible for lipoxygenase initiated lipid peroxidation. This transient character of uranium stress responses in leaves was emphasized by results of lipoxygenase (LOX2) and antioxidative enzyme transcript levels, enzyme capacities and glutathione concentrations both in time as with concentration. The ascorbate redox balance seemed an important modulator of uranium stress responses in the leaves as in addition to the previous transient responses, the total ascorbate concentration and ascorbate/dehydroascorbate redox balance increased in a concentration and time dependent manner. This could represent either a slow transient response or a stable increase with regard to plant acclimation to uranium stress. Copyright �

A microencapsulation process of liquid mercury by sulfur polymer stabilization/solidification technology. Part II: Durability of materials

Energy Technology Data Exchange (ETDEWEB)

Lopez-Delgado, A.; Guerrero, A.; Lopez, F. A.; Perez, C.; Alguacil, F. J.

2012-11-01

Under the European LIFE Program a microencapsulation process was developed for liquid mercury using Sulfur Polymer Stabilization/Solidification (SPSS) technology, obtaining a stable concrete-like sulfur matrix that allows the immobilization of mercury for long-term storage. The process description and characterization of the materials obtained were detailed in Part I. The present document, Part II, reports the results of different tests carried out to determine the durability of Hg-S concrete samples with very high mercury content (up to 30 % w/w). Different UNE and RILEM standard test methods were applied, such as capillary water absorption, low pressure water permeability, alkali/acid resistance, salt mist aging, freeze-thaw resistance and fire performance. The samples exhibited no capillarity and their resistance in both alkaline and acid media was very high. They also showed good resistance to very aggressive environments such as spray salt mist, freeze-thaw and dry-wet. The fire hazard of samples at low heat output was negligible. (Author)

PACE. A Program for Acquiring Competence in Entrepreneurship. Part II: Becoming an Entrepreneur. Unit A: Developing the Business Plan. Research and Development Series No. 194 B-1.

Science.gov (United States)

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

This three-part curriculum for entrepreneurship education is primarily for postsecondary level, including four-year colleges and adult education, but it can be adapted for special groups or vocational teacher education. The emphasis of the seven instructional units in Part II is establishing a business. Unit A focuses on developing a business…

Multiobjective Optimization for Fixture Locating Layout of Sheet Metal Part Using SVR and NSGA-II

Directory of Open Access Journals (Sweden)

Yuan Yang

2017-01-01

Full Text Available Fixture plays a significant role in determining the sheet metal part (SMP spatial position and restraining its excessive deformation in many manufacturing operations. However, it is still a difficult task to design and optimize SMP fixture locating layout at present because there exist multiple conflicting objectives and excessive computational cost of finite element analysis (FEA during the optimization process. To this end, a new multiobjective optimization method for SMP fixture locating layout is proposed in this paper based on the support vector regression (SVR surrogate model and the elitist nondominated sorting genetic algorithm (NSGA-II. By using ABAQUS™ Python script interface, a parametric FEA model is established. And the fixture locating layout is treated as design variables, while the overall deformation and maximum deformation of SMP under external forces are as the multiple objective functions. First, a limited number of training and testing samples are generated by combining Latin hypercube design (LHD with FEA. Second, two SVR prediction models corresponding to the multiple objectives are established by learning from the limited training samples and are integrated as the multiobjective optimization surrogate model. Third, NSGA-II is applied to determine the Pareto optimal solutions of SMP fixture locating layout. Finally, a multiobjective optimization for fixture locating layout of an aircraft fuselage skin case is conducted to illustrate and verify the proposed method.

Secondary recurrent miscarriage is associated with previous male birth.

LENUS (Irish Health Repository)

Ooi, Poh Veh

2012-01-31

Secondary recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses after delivery of a viable infant. Previous reports suggest that a firstborn male child is associated with less favourable subsequent reproductive potential, possibly due to maternal immunisation against male-specific minor histocompatibility antigens. In a retrospective cohort study of 85 cases of secondary RM we aimed to determine if secondary RM was associated with (i) gender of previous child, maternal age, or duration of miscarriage history, and (ii) increased risk of pregnancy complications. Fifty-three women (62.0%; 53\\/85) gave birth to a male child prior to RM compared to 32 (38.0%; 32\\/85) who gave birth to a female child (p=0.002). The majority (91.7%; 78\\/85) had uncomplicated, term deliveries and normal birth weight neonates, with one quarter of the women previously delivered by Caesarean section. All had routine RM investigations and 19.0% (16\\/85) had an abnormal result. Fifty-seven women conceived again and 33.3% (19\\/57) miscarried, but there was no significant difference in failure rates between those with a previous male or female child (13\\/32 vs. 6\\/25, p=0.2). When patients with abnormal results were excluded, or when women with only one previous child were considered, there was still no difference in these rates. A previous male birth may be associated with an increased risk of secondary RM but numbers preclude concluding whether this increases recurrence risk. The suggested association with previous male birth provides a basis for further investigations at a molecular level.

Secondary recurrent miscarriage is associated with previous male birth.

LENUS (Irish Health Repository)

Ooi, Poh Veh

2011-01-01

Secondary recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses after delivery of a viable infant. Previous reports suggest that a firstborn male child is associated with less favourable subsequent reproductive potential, possibly due to maternal immunisation against male-specific minor histocompatibility antigens. In a retrospective cohort study of 85 cases of secondary RM we aimed to determine if secondary RM was associated with (i) gender of previous child, maternal age, or duration of miscarriage history, and (ii) increased risk of pregnancy complications. Fifty-three women (62.0%; 53\\/85) gave birth to a male child prior to RM compared to 32 (38.0%; 32\\/85) who gave birth to a female child (p=0.002). The majority (91.7%; 78\\/85) had uncomplicated, term deliveries and normal birth weight neonates, with one quarter of the women previously delivered by Caesarean section. All had routine RM investigations and 19.0% (16\\/85) had an abnormal result. Fifty-seven women conceived again and 33.3% (19\\/57) miscarried, but there was no significant difference in failure rates between those with a previous male or female child (13\\/32 vs. 6\\/25, p=0.2). When patients with abnormal results were excluded, or when women with only one previous child were considered, there was still no difference in these rates. A previous male birth may be associated with an increased risk of secondary RM but numbers preclude concluding whether this increases recurrence risk. The suggested association with previous male birth provides a basis for further investigations at a molecular level.

Study of diffuse H II regions potentially forming part of the gas streams around Sgr A*

Science.gov (United States)

Armijos-Abendaño, J.; López, E.; Martín-Pintado, J.; Báez-Rubio, A.; Aravena, M.; Requena-Torres, M. A.; Martín, S.; Llerena, M.; Aldás, F.; Logan, C.; Rodríguez-Franco, A.

2018-05-01

We present a study of diffuse extended ionized gas towards three clouds located in the Galactic Centre (GC). One line of sight (LOS) is towards the 20 km s-1 cloud (LOS-0.11) in the Sgr A region, another LOS is towards the 50 km s-1 cloud (LOS-0.02), also in Sgr A, while the third is towards the Sgr B2 cloud (LOS+0.693). The emission from the ionized gas is detected from Hnα and Hmβ radio recombination lines (RRLs). Henα and Hemβ RRL emission is detected with the same n and m as those from the hydrogen RRLs only towards LOS+0.693. RRLs probe gas with positive and negative velocities towards the two Sgr A sources. The Hmβ to Hnα ratios reveal that the ionized gas is emitted under local thermodynamic equilibrium conditions in these regions. We find a He to H mass fraction of 0.29±0.01 consistent with the typical GC value, supporting the idea that massive stars have increased the He abundance compared to its primordial value. Physical properties are derived for the studied sources. We propose that the negative velocity component of both Sgr A sources is part of gas streams considered previously to model the GC cloud kinematics. Associated massive stars with what are presumably the closest H II regions to LOS-0.11 (positive velocity gas), LOS-0.02, and LOS+0.693 could be the main sources of ultraviolet photons ionizing the gas. The negative velocity components of both Sgr A sources might be ionized by the same massive stars, but only if they are in the same gas stream.

Mechanical performance of carbon-epoxy laminates. Part II: quasi-static and fatigue tensile properties

Directory of Open Access Journals (Sweden)

José Ricardo Tarpani

2006-06-01

Full Text Available In Part II of this work, quasi-static tensile properties of four aeronautical grade carbon-epoxy composite laminates, in both the as-received and pre-fatigued states, have been determined and compared. Quasi-static mechanical properties assessed were tensile strength and stiffness, tenacity (toughness at the maximum load and for a 50% load drop-off. In general, as-molded unidirectional cross-ply carbon fiber (tape reinforcements impregnated with either standard or rubber-toughened epoxy resin exhibited the maximum performance. The materials also displayed a significant tenacification (toughening after exposed to cyclic loading, resulting from the increased stress (the so-called wear-in phenomenon and/or strain at the maximum load capacity of the specimens. With no exceptions, two-dimensional woven textile (fabric pre-forms fractured catastrophically under identical cyclic loading conditions imposed to the fiber tape architecture, thus preventing their residual properties from being determined.

Magnetic resonance imaging of the elbow. Part II: Abnormalities of the ligaments, tendons, and nerves

Energy Technology Data Exchange (ETDEWEB)

Kijowski, Richard; Tuite, Michael; Sanford, Matthew [University of Wisconsin Hospital, Department of Radiology, Madison, WI (United States)

2005-01-01

Part II of this comprehensive review on magnetic resonance imaging of the elbow discusses the role of magnetic resonance imaging in evaluating patients with abnormalities of the ligaments, tendons, and nerves of the elbow. Magnetic resonance imaging can yield high-quality multiplanar images which are useful in evaluating the soft tissue structures of the elbow. Magnetic resonance imaging can detect tears of the ulnar collateral ligament and lateral collateral ligament of the elbow with high sensitivity and specificity. Magnetic resonance imaging can determine the extent of tendon pathology in patients with medial epicondylitis and lateral epicondylitis. Magnetic resonance imaging can detect tears of the biceps tendon and triceps tendon and can distinguishing between partial and complete tendon rupture. Magnetic resonance imaging is also helpful in evaluating patients with nerve disorders at the elbow. (orig.)

The PIP-II Conceptual Design Report

Energy Technology Data Exchange (ETDEWEB)

Ball, M. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Burov, A. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Chase, B. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Chakravarty, A. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Chen, A. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Dixon, S. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Edelen, J. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Grassellino, A. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Johnson, D. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Holmes, S. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Kazakov, S. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Klebaner, A. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Kourbanis, I. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Leveling, A. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Melnychuk, O. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Neuffer, D. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Nicol, T. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Ostiguy, J. -F. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Pasquinelli, R. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Passarelli, D. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Ristori, L. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Pellico, W. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Patrick, J. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Prost, L. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Rakhno, I. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Saini, A. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Schappert, W. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Shemyakin, A. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Steimel, J. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Scarpine, V. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Vivoli, A. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Warner, A. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Yakovlev, V. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Ostroumov, P. [Argonne National Lab. (ANL), Argonne, IL (United States); Conway, Z. [Argonne National Lab. (ANL), Argonne, IL (United States)

2017-03-01

The Proton Improvement Plan-II (PIP-II) encompasses a set of upgrades and improvements to the Fermilab accelerator complex aimed at supporting a world-leading neutrino program over the next several decades. PIP-II is an integral part of the strategic plan for U.S. High Energy Physics as described in the Particle Physics Project Prioritization Panel (P5) report of May 2014 and formalized through the Mission Need Statement approved in November 2015. As an immediate goal, PIP-II is focused on upgrades to the Fermilab accelerator complex capable of providing proton beam power in excess of 1 MW on target at the initiation of the Long Baseline Neutrino Facility/Deep Underground Neutrino Experiment (LBNF/DUNE) program, currently anticipated for the mid- 2020s. PIP-II is a part of a longer-term goal of establishing a high-intensity proton facility that is unique within the world, ultimately leading to multi-MW capabilities at Fermilab....

Plasma Astrophysics, part II Reconnection and Flares

CERN Document Server

Somov, Boris V

2007-01-01

This well-illustrated monograph is devoted to classic fundamentals, current practice, and perspectives of modern plasma astrophysics. The first part is unique in covering all the basic principles and practical tools required for understanding and working in plasma astrophysics. The second part presents the physics of magnetic reconnection and flares of electromagnetic origin in space plasmas within the solar system; single and double stars, relativistic objects, accretion disks, and their coronae are also covered. This book is designed mainly for professional researchers in astrophysics. However, it will also be interesting and useful to graduate students in space sciences, geophysics, as well as advanced students in applied physics and mathematics seeking a unified view of plasma physics and fluid mechanics.

A comprehensive review with potential significance during skull base and neck operations, Part II: glossopharyngeal, vagus, accessory, and hypoglossal nerves and cervical spinal nerves 1-4.

Science.gov (United States)

Shoja, Mohammadali M; Oyesiku, Nelson M; Shokouhi, Ghaffar; Griessenauer, Christoph J; Chern, Joshua J; Rizk, Elias B; Loukas, Marios; Miller, Joseph H; Tubbs, R Shane

2014-01-01

Knowledge of the possible neural interconnections found between the lower cranial and upper cervical nerves may prove useful to surgeons who operate on the skull base and upper neck regions in order to avoid inadvertent traction or transection. We review the literature regarding the anatomy, function, and clinical implications of the complex neural networks formed by interconnections between the lower cranial and upper cervical nerves. A review of germane anatomic and clinical literature was performed. The review is organized into two parts. Part I discusses the anastomoses between the trigeminal, facial, and vestibulocochlear nerves or their branches and other nerve trunks or branches in the vicinity. Part II deals with the anastomoses between the glossopharyngeal, vagus, accessory and hypoglossal nerves and their branches or between these nerves and the first four cervical spinal nerves; the contribution of the autonomic nervous system to these neural plexuses is also briefly reviewed. Part II is presented in this article. Extensive and variable neural anastomoses exist between the lower cranial nerves and between the upper cervical nerves in such a way that these nerves with their extra-axial communications can be collectively considered a plexus. Copyright © 2013 Wiley Periodicals, Inc.

A microencapsulation process of liquid mercury by sulfur polymer stabilization/solidification technology. Part II: Durability of materials

Directory of Open Access Journals (Sweden)

López-Delgado, A.

2012-02-01

Full Text Available Under the European LIFE Program a microencapsulation process was developed for liquid mercury using Sulfur Polymer Stabilization/Solidification (SPSS technology, obtaining a stable concrete-like sulfur matrix that allows the immobilization of mercury for long-term storage. The process description and characterization of the materials obtained were detailed in Part I. The present document, Part II, reports the results of different tests carried out to determine the durability of Hg-S concrete samples with very high mercury content (up to 30 % w/w. Different UNE and RILEM standard test methods were applied, such as capillary water absorption, low pressure water permeability, alkali/acid resistance, salt mist aging, freeze-thaw resistance and fire performance. The samples exhibited no capillarity and their resistance in both alkaline and acid media was very high. They also showed good resistance to very aggressive environments such as spray salt mist, freeze-thaw and dry-wet. The fire hazard of samples at low heat output was negligible.

Dentro del Programa Europeo LIFE, se ha desarrollado un proceso de microencapsulación de mercurio liquido, utilizando la tecnología de estabilización/solidificación con azufre polimérico (SPSS. Como resultado se ha obtenido un material estable tipo concreto que permite la inmovilización de mercurio y su almacenamiento a largo plazo. La descripción del proceso y la caracterización de los materiales obtenidos, denominados concretos Hg-S, se detallan en la Parte I. El presente trabajo, Parte II, incluye los resultados de los diferentes ensayos realizados para determinar la durabilidad de las muestras de concreto Hg-S con un contenido de mercurio de hasta el 30 %. Se han utilizado diferentes métodos de ensayo estándar, UNE y RILEM, para determinar propiedades como la absorción de agua por capilaridad, la permeabilidad de agua a baja presión, la resistencia a álcali y ácido, el comportamiento en

Phase II study of a 3-day schedule with topotecan and cisplatin in patients with previously untreated small cell lung cancer and extensive disease

DEFF Research Database (Denmark)

Sorensen, M.; Lassen, Ulrik Niels; Jensen, Peter Buhl

2008-01-01

INTRODUCTION: Treatment with a topoisomerase I inhibitor in combination with a platinum results in superior or equal survival compared with etoposide-based treatment in extensive disease small cell lung cancer (SCLC). Five-day topotecan is inconvenient and therefore shorter schedules of topotecan...... and cisplatin are needed. The aim of this phase II study was to establish the response rate and response duration in chemo-naive patients with SCLC receiving a 3-day topotecan and cisplatin schedule. METHODS: Simons optimal two-stage design was used. Patients with previously untreated extensive disease SCLC...... age was 59 (range 44-74), 79% had performance status 0 or 1. Thirty-one patients completed all six cycles. Grade 3/4 anemia, neutrocytopenia, and thrombocytopenia were recorded in 9.5%, 66.7%, and 21.4% of patients, respectively. Fourteen percent of patients experienced neutropenic fever. No episodes...

Joint stability characteristics of the ankle complex in female athletes with histories of lateral ankle sprain, part II: clinical experience using arthrometric measurement.

Science.gov (United States)

Kovaleski, John E; Heitman, Robert J; Gurchiek, Larry R; Hollis, J M; Liu, Wei; Pearsall, Albert W

2014-01-01

This is part II of a 2-part series discussing stability characteristics of the ankle complex. In part I, we used a cadaver model to examine the effects of sectioning the lateral ankle ligaments on anterior and inversion motion and stiffness of the ankle complex. In part II, we wanted to build on and apply these findings to the clinical assessment of ankle-complex motion and stiffness in a group of athletes with a history of unilateral ankle sprain. To examine ankle-complex motion and stiffness in a group of athletes with reported history of lateral ankle sprain. Cross-sectional study. University research laboratory. Twenty-five female college athletes (age = 19.4 ± 1.4 years, height = 170.2 ± 7.4 cm, mass = 67.3 ± 10.0 kg) with histories of unilateral ankle sprain. All ankles underwent loading with an ankle arthrometer. Ankles were tested bilaterally. The dependent variables were anterior displacement, anterior end-range stiffness, inversion rotation, and inversion end-range stiffness. Anterior displacement of the ankle complex did not differ between the uninjured and sprained ankles (P = .37), whereas ankle-complex rotation was greater for the sprained ankles (P = .03). The sprained ankles had less anterior and inversion end-range stiffness than the uninjured ankles (P ankle-complex laxity and end-range stiffness were detected in ankles with histories of sprain. These results indicate the presence of altered mechanical characteristics in the soft tissues of the sprained ankles.

Converting Eucalyptus biomass into ethanol: Financial and sensitivity analysis in a co-current dilute acid process. Part II

International Nuclear Information System (INIS)

Gonzalez, R.; Treasure, T.; Phillips, R.; Jameel, H.; Saloni, D.; Wright, J.; Abt, R.

2011-01-01

The technical and financial performance of high yield Eucalyptus biomass in a co-current dilute acid pretreatment followed by enzymatic hydrolysis process was simulated using WinGEMS registered and Excel registered . Average ethanol yield per dry Mg of Eucalyptus biomass was approximately 347.6 L of ethanol (with average carbohydrate content in the biomass around 66.1%) at a cost of 0.49 L -1 of ethanol, cash cost of ∝0.46 L -1 and CAPEX of 1.03 L -1 of ethanol. The main cost drivers are: biomass, enzyme, tax, fuel (gasoline), depreciation and labor. Profitability of the process is very sensitive to biomass cost, carbohydrate content (%) in biomass and enzyme cost. Biomass delivered cost was simulated and financially evaluated in Part I; here in Part II the conversion of this raw material into cellulosic ethanol using the dilute acid process is evaluated. (author)

[The external patello-tibial transfixation (EPTT). Part II: Clinical application and results].

Science.gov (United States)

Ishaque, B; Gotzen, L; Ziring, E; Petermann, J

1999-07-01

In part I of the paper the biomechanical and technical background of the EPTT using the MPT fixator and the indications for this procedure have been described. In part II we report about the clinical application of the EPTT in 67 patients with a wide spectrum of repairs and reconstructions of the extensor mechanism. 48 patients had fresh injuries, 18 of them with severe concomitant knee lesions and 19 patients had neglected rsp. unsuccessfully operated injuries. There were 4 deep infections, two of them related to the MPT fixator. In the patients with uneventful healing the fixator remained in place for 7.3 weeks in average. The clinical, isokinetic and radiological results were reviewed in 17 patients with an average follow-up time of 37.3 months. There were 5 patients with partial patellectomy and tendon reattachment because of lower patella pole comminution and 12 patients with tendon reattachment ruptured at the inferior patella pole or suture repair in midsubstance rupture. The clinical results according to the IKDC score were rated in 3 patients as normal, in 10 patients as nearly normal and in 4 patients as abnormal. This rating was highly dependend on the subjective judgement by the patients who considered their operated knees not as normal as the contralateral knees. From our clinical experiences and results we can derive that the EPTT enables the surgical management of extensor mechanism disruptions with a minimum of internal fixation material and provides a safe protection of the repairs and reconstructions during the healing period. The EPTT allows immediate unrestricted functional rehabilitation and early walking without crutches. Thus the EPTT represents an effective alternative to the patello-tibial cerclage with a wire or synthetic ligaments.

Long-term solar activity and terrestrial connections. Part II: at the beckon of the sun?

Directory of Open Access Journals (Sweden)

N. D. Diamantides

1998-05-01

Full Text Available The research task described herein aims at the structuring of an analytical tool that traces the time course of geophysical phenomena, regional or global, and compares it to the course of long-term solar conditions, long-term meaning decades or a few centuries. The model is based on the premise that since in a last analysis the preponderance of atmospheric, hydrospheric, and, possibly, some aspects of geospheric phenomena are, or have been, powered by energy issuing from the sun - either now or in the past - the long-term behavior of such phenomena is ultimately "connected" to long-term changes occurring in the sun itself. Accordingly, the proposed research firstly derives and models a stable surrogate pattern for the long-term solar activity, secondly introduces a transfer-function algorithm for modeling the connection between the surrogate and terrestrial phenomena viewed as partners in the connection, and thirdly probes the connection outcome for episodic or unanticipated effects that may arise due to the fact that in the present context, the connection, should it exist, is very likely nonlinear. Part I of the study presents the theory of the concept, while Part II demonstrates the concept's pertinence to a number of terrestrial phenomena.Key words. Solar activity · Kolmogorov algorithm

PACE. A Program for Acquiring Competence in Entrepreneurship. Part II: Becoming an Entrepreneur. Unit F: How to Finance the Business. Research and Development Series No. 194 B-6.

Science.gov (United States)

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

This three-part curriculum for entrepreneurship education is primarily for postsecondary level, including four-year colleges and adult education, but it can be adapted for special groups or vocational teacher education. The emphasis of the seven instructional units in Part II is establishing a business. Unit F focuses on financing the business. It…

PACE. A Program for Acquiring Competence in Entrepreneurship. Part II: Becoming an Entrepreneur. Unit B: Where to Locate the Business. Research and Development Series No. 194 B-2.

Science.gov (United States)

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

This three-part curriculum for entrepreneurship education is primarily for postsecondary level, including four-year colleges and adult education, but it can be adapted for special groups or vocational teacher education. The emphasis of the seven instructional units in Part II is on establishing a business. Unit B focuses on choosing a business…

PACE. A Program for Acquiring Competence in Entrepreneurship. Part II: Becoming an Entrepreneur. Unit C: Legal Issues and Small Business. Research and Development Series No. 194 B-3.

Science.gov (United States)

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

This three-part curriculum for entrepreneurship education is primarily for postsecondary level, including four-year colleges and adult education, but it can be adapted for special groups or vocational teacher education. The emphasis of the seven instructional units in Part II is establishing a business. Unit C focuses on legal issues that affect…

PACE. A Program for Acquiring Competence in Entrepreneurship. Part II: Becoming an Entrepreneur. Unit D: Government Regulations and Small Businesses. Research and Development Series No. 194 B-4.

Science.gov (United States)

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

This three-part curriculum for entrepreneurship education is primarily for postsecondary level, including four-year colleges and adult education, but it can be adapted for special groups or vocational teacher education. The emphasis of the seven instructional units in Part II is establishing a business. Unit D focuses on business regulations at…

Concurrent Chemoradiotherapy Followed by Consolidation Chemotherapy With Bi-Weekly Docetaxel and Carboplatin for Stage III Unresectable, Non-Small-Cell Lung Cancer: Clinical Application of a Protocol Used in a Previous Phase II Study

International Nuclear Information System (INIS)

Saitoh, Jun-Ichi; Saito, Yoshihiro; Kazumoto, Tomoko; Kudo, Shigehiro; Yoshida, Daisaku; Ichikawa, Akihiro; Sakai, Hiroshi; Kurimoto, Futoshi; Kato, Shingo; Shibuya, Kei

2012-01-01

Purpose: To assess the clinical applicability of a protocol evaluated in a previously reported phase II study of concurrent chemoradiotherapy followed by consolidation chemotherapy with bi-weekly docetaxel and carboplatin in patients with stage III, unresectable, non-small-cell lung cancer (NSCLC). Methods and Materials: Between January 2000 and March 2006, 116 previously untreated patients with histologically proven, stage III NSCLC were treated with concurrent chemoradiotherapy. Radiation therapy was administered in 2-Gy daily fractions to a total dose of 60 Gy in combination with docetaxel, 30 mg/m 2 , and carboplatin at an area under the curve value of 3 every 2 weeks during and after radiation therapy. Results: The median survival time for the entire group was 25.5 months. The actuarial 2-year and 5-year overall survival rates were 53% and 31%, respectively. The 3-year cause-specific survival rate was 60% in patients with stage IIIA disease, whereas it was 35% in patients with stage IIIB disease (p = 0.007). The actuarial 2-year and 5-year local control rates were 62% and 55%, respectively. Acute hematologic toxicities of Grade ≥3 severity were observed in 20.7% of patients, while radiation pneumonitis and esophagitis of Grade ≥3 severity were observed in 2.6% and 1.7% of patients, respectively. Conclusions: The feasibility of the protocol used in the previous phase II study was reconfirmed in this series, and excellent treatment results were achieved.

Concurrent Chemoradiotherapy Followed by Consolidation Chemotherapy With Bi-Weekly Docetaxel and Carboplatin for Stage III Unresectable, Non-Small-Cell Lung Cancer: Clinical Application of a Protocol Used in a Previous Phase II Study

Energy Technology Data Exchange (ETDEWEB)

Saitoh, Jun-Ichi, E-mail: junsaito@sannet.ne.jp [Division of Radiation Oncology, Saitama Cancer Center, Saitama (Japan); Saito, Yoshihiro; Kazumoto, Tomoko; Kudo, Shigehiro; Yoshida, Daisaku; Ichikawa, Akihiro [Division of Radiation Oncology, Saitama Cancer Center, Saitama (Japan); Sakai, Hiroshi; Kurimoto, Futoshi [Division of Respiratory Disease, Saitama Cancer Center, Saitama (Japan); Kato, Shingo [Research Center Hospital for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba (Japan); Shibuya, Kei [Department of Radiation Oncology, Gunma University Graduate School of Medicine, Gunma (Japan)

2012-04-01

Purpose: To assess the clinical applicability of a protocol evaluated in a previously reported phase II study of concurrent chemoradiotherapy followed by consolidation chemotherapy with bi-weekly docetaxel and carboplatin in patients with stage III, unresectable, non-small-cell lung cancer (NSCLC). Methods and Materials: Between January 2000 and March 2006, 116 previously untreated patients with histologically proven, stage III NSCLC were treated with concurrent chemoradiotherapy. Radiation therapy was administered in 2-Gy daily fractions to a total dose of 60 Gy in combination with docetaxel, 30 mg/m{sup 2}, and carboplatin at an area under the curve value of 3 every 2 weeks during and after radiation therapy. Results: The median survival time for the entire group was 25.5 months. The actuarial 2-year and 5-year overall survival rates were 53% and 31%, respectively. The 3-year cause-specific survival rate was 60% in patients with stage IIIA disease, whereas it was 35% in patients with stage IIIB disease (p = 0.007). The actuarial 2-year and 5-year local control rates were 62% and 55%, respectively. Acute hematologic toxicities of Grade {>=}3 severity were observed in 20.7% of patients, while radiation pneumonitis and esophagitis of Grade {>=}3 severity were observed in 2.6% and 1.7% of patients, respectively. Conclusions: The feasibility of the protocol used in the previous phase II study was reconfirmed in this series, and excellent treatment results were achieved.

Subsequent childbirth after a previous traumatic birth.

Science.gov (United States)

Beck, Cheryl Tatano; Watson, Sue

2010-01-01

Nine percent of new mothers in the United States who participated in the Listening to Mothers II Postpartum Survey screened positive for meeting the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for posttraumatic stress disorder after childbirth. Women who have had a traumatic birth experience report fewer subsequent children and a longer length of time before their second baby. Childbirth-related posttraumatic stress disorder impacts couples' physical relationship, communication, conflict, emotions, and bonding with their children. The purpose of this study was to describe the meaning of women's experiences of a subsequent childbirth after a previous traumatic birth. Phenomenology was the research design used. An international sample of 35 women participated in this Internet study. Women were asked, "Please describe in as much detail as you can remember your subsequent pregnancy, labor, and delivery following your previous traumatic birth." Colaizzi's phenomenological data analysis approach was used to analyze the stories of the 35 women. Data analysis yielded four themes: (a) riding the turbulent wave of panic during pregnancy; (b) strategizing: attempts to reclaim their body and complete the journey to motherhood; (c) bringing reverence to the birthing process and empowering women; and (d) still elusive: the longed-for healing birth experience. Subsequent childbirth after a previous birth trauma has the potential to either heal or retraumatize women. During pregnancy, women need permission and encouragement to grieve their prior traumatic births to help remove the burden of their invisible pain.

Focus group report - part II

International Nuclear Information System (INIS)

1997-12-01

The Waste Policy Institute, through a cooperative agreement with the U.S. Department of Energy (DOE) Office of Science and Technology (OST) conducted a focus group with members of the Hanford Advisory Board (HAB), interviews with tribal government representatives, and a survey of Oak Ridge Local Oversight Committee (LOC) and Site Specific Advisory Board (SSAB) members. The purpose was to understand what members of the interested and involved public want to know about technology development and ways to get that information to them. These data collection activities were used as a follow-up to two previously held focus groups with the general public near Idaho National Engineering and Environmental Laboratory (INEEL) and the Savannah River Site (SRS). Most participants from the first two focus groups said they did not have time and/or were not interested in participating in technology decision-making. They said they would prefer to defer to members of their communities who are interested and want to be involved in technology decision-making

Acuity and case management: a healthy dose of outcomes, part II.

Science.gov (United States)

Craig, Kathy; Huber, Diane L

2007-01-01

This is the second of a 3-part series presenting 2 effective applications-acuity and dosage-that describe how the business case for case management (CM) can be made. In Part I, dosage and acuity concepts were explained as client need-severity, CM intervention-intensity, and CM activity-dose prescribed by amount, frequency, duration, and breadth of activities. Part I also featured a specific exemplar, the CM Acuity Tool, and described how to use acuity to identify and score the complexity of a CM case. Appropriate dosage prescription of CM activity was discussed. Part II further explains dosage and presents two acuity instruments, the Acuity Tool and AccuDiff. Details are provided that show how these applications produce opportunities for better communication about CM cases and for more accurate measurement of the right content that genuinely reflects the essentials of CM practice. The information contained in the 3-part series applies to all CM practice settings and contains ideas and recommendations useful to CM generalists, specialists, and supervisors, plus business and outcomes managers. The Acuity Tools Project was developed from frontline CM practice in one large, national telephonic CM company. Dosage: A literature search failed to find research into dosage of a behavioral intervention. The Huber-Hall model was developed and tested in a longitudinal study of CM models in substance abuse treatment and reported in the literature. Acuity: A structured literature search and needs assessment launched the development of the suite of acuity tools. A gap analysis identified that an instrument to assign and measure case acuity specific to CM activities was needed. Clinical experts, quality specialists, and business analysts (n = 7) monitored the development and testing of the tools, acuity concepts, scores, differentials, and their operating principles and evaluated the validity of the Acuity Tools' content related to CM activities. During the pilot phase of

PACE. A Program for Acquiring Competence in Entrepreneurship. Part II: Becoming an Entrepreneur. Unit E: Choosing the Type of Ownership. Research and Development Series No. 194 B-5.

Science.gov (United States)

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

This three-part curriculum for entrepreneurship education is primarily for postsecondary level, including four-year colleges and adult education, but it can be adapted for special groups or vocational teacher education. The emphasis of the seven instructional units in Part II is establishing a business. Unit E focuses on the three major types of…

Interaction of Zn(II) with hematite nanoparticles and microparticles: Part 2. ATR-FTIR and EXAFS study of the aqueous Zn(II)/oxalate/hematite ternary system.

Science.gov (United States)

Ha, Juyoung; Trainor, Thomas P; Farges, François; Brown, Gordon E

2009-05-19

Sorption of Zn(II) to hematite nanoparticles (HN) (av diam=10.5 nm) and microparticles (HM) (av diam=550 nm) was studied in the presence of oxalate anions (Ox2-(aq)) in aqueous solutions as a function of total Zn(II)(aq) to total Ox2-(aq) concentration ratio (R=[Zn(II)(aq)]tot/[Ox2-(aq)]tot) at pH 5.5. Zn(II) uptake is similar in extent for both the Zn(II)/Ox/HN and Zn(II)/Ox/HM ternary systems and the Zn(II)/HN binary system at [Zn(II)(aq)](tot)system than for the Zn(II)/Ox/HM ternary and the Zn(II)/HN and Zn(II)/HM binary systems at [Zn(II)(aq)]tot>4 mM. In contrast, Zn(II) uptake for the Zn(II)/HM binary system is a factor of 2 greater than that for the Zn(II)/Ox/HM and Zn(II)/Ox/HN ternary systems and the Zn(II)/HN binary system at [Zn(II)(aq)]totternary system at both R values examined (0.16 and 0.68), attenuated total reflectance Fourier transform infrared (ATR-FTIR) results are consistent with the presence of inner-sphere oxalate complexes and outer-sphere ZnOx(aq) complexes, and/or type A ternary complexes. In addition, extended X-ray absorption fine structure (EXAFS) spectroscopic results suggest that type A ternary surface complexes (i.e., >O2-Zn-Ox) are present. In the Zn(II)/Ox/HN ternary system at R=0.15, ATR-FTIR results indicate the presence of inner-sphere oxalate and outer-sphere ZnOx(aq) complexes; the EXAFS results provide no evidence for inner-sphere Zn(II) complexes or type A ternary complexes. In contrast, ATR-FTIR results for the Zn/Ox/HN sample with R = 0.68 are consistent with a ZnOx(s)-like surface precipitate and possibly type B ternary surface complexes (i.e., >O2-Ox-Zn). EXAFS results are also consistent with the presence of ZnOx(s)-like precipitates. We ascribe the observed increase of Zn(II)(aq) uptake in the Zn(II)/Ox/HN ternary system at [Zn(II)(aq)]tot>or=4 mM relative to the Zn(II)/Ox/HM ternary system to formation of a ZnOx(s)-like precipitate at the hematite nanoparticle/water interface.

Japanese contributions to IAEA INTOR workshop, phase two A, part 2, chapter I: introduction, and chapter II: summary

International Nuclear Information System (INIS)

Mori, Sigeru; Tomabechi, Ken; Fujisawa, Noboru; Iida, Hiromasa; Sugihara, Masayoshi; Seki, Masahiro; Honda, Tsutomu; Kasai, Masao; Itoh, Shin-ichi.

1985-07-01

This report corresponds to Chapters I and II of Japanese contribution report to IAEA INTOR Workshop, Phase Two A, Part 2. The major objectives of the INTOR workshop, Phase Two A, Part 2 are to study critical technical issues, and to assess scientific and technical data bases, and to finally upgrade the INTOR design concept. To study critical technical issues that affect the feasibility or practicability of the INTOR design concept, the following five groups are organized; (A) Impurity control, (B) RF heating and current drive, (C) Transient electromagnetics, (D) Maintainability, (E) Technical benefit. In addition to those groups, the three disciplinary groups are organized to assess the worldiode scientific and technical data bases that exist now and that will exist 4-5 years to support the detailed design and construction of an INTOR-like machine, and to identify additional R D that is required; (F) Physics, (G) Engineering, (H) Nuclear. (author)

The Mixed Waste Management Facility: Technology selection and implementation plan, Part 2, Support processes

International Nuclear Information System (INIS)

Streit, R.D.; Couture, S.A.

1995-03-01

The purpose of this document is to establish the foundation for the selection and implementation of technologies to be demonstrated in the Mixed Waste Management Facility, and to select the technologies for initial pilot-scale demonstration. Criteria are defined for judging demonstration technologies, and the framework for future technology selection is established. On the basis of these criteria, an initial suite of technologies was chosen, and the demonstration implementation scheme was developed. Part 1, previously released, addresses the selection of the primary processes. Part II addresses process support systems that are considered ''demonstration technologies.'' Other support technologies, e.g., facility off-gas, receiving and shipping, and water treatment, while part of the integrated demonstration, use best available commercial equipment and are not selected against the demonstration technology criteria

Introduction of organic/hydro-organic matrices in inductively coupled plasma optical emission spectrometry and mass spectrometry: a tutorial review. Part II. Practical considerations.

Science.gov (United States)

Leclercq, Amélie; Nonell, Anthony; Todolí Torró, José Luis; Bresson, Carole; Vio, Laurent; Vercouter, Thomas; Chartier, Frédéric

2015-07-23

Inductively coupled plasma optical emission spectrometry (ICP-OES) and mass spectrometry (ICP-MS) are increasingly used to carry out analyses in organic/hydro-organic matrices. The introduction of such matrices into ICP sources is particularly challenging and can be the cause of numerous drawbacks. This tutorial review, divided in two parts, explores the rich literature related to the introduction of organic/hydro-organic matrices in ICP sources. Part I provided theoretical considerations associated with the physico-chemical properties of such matrices, in an attempt to understand the induced phenomena. Part II of this tutorial review is dedicated to more practical considerations on instrumentation, instrumental and operating parameters, as well as analytical strategies for elemental quantification in such matrices. Two important issues are addressed in this part: the first concerns the instrumentation and optimization of instrumental and operating parameters, pointing out (i) the description, benefits and drawbacks of different kinds of nebulization and desolvation devices and the impact of more specific instrumental parameters such as the injector characteristics and the material used for the cone; and, (ii) the optimization of operating parameters, for both ICP-OES and ICP-MS. Even if it is at the margin of this tutorial review, Electrothermal Vaporization and Laser Ablation will also be shortly described. The second issue is devoted to the analytical strategies for elemental quantification in such matrices, with particular insight into the isotope dilution technique, particularly used in speciation analysis by ICP-coupled separation techniques. Copyright © 2015 Elsevier B.V. All rights reserved.

Multiscale modeling, simulations, and experiments of coating growth on nanofibers. Part II. Deposition

International Nuclear Information System (INIS)

Buldum, A.; Clemons, C.B.; Dill, L.H.; Kreider, K.L.; Young, G.W.; Zheng, X.; Evans, E.A.; Zhang, G.; Hariharan, S.I.

2005-01-01

This work is Part II of an integrated experimental/modeling investigation of a procedure to coat nanofibers and core-clad nanostructures with thin-film materials using plasma-enhanced physical vapor deposition. In the experimental effort, electrospun polymer nanofibers are coated with aluminum materials under different operating conditions to observe changes in the coating morphology. This procedure begins with the sputtering of the coating material from a target. Part I [J. Appl. Phys. 98, 044303 (2005)] focused on the sputtering aspect and transport of the sputtered material through the reactor. That reactor level model determines the concentration field of the coating material. This field serves as input into the present species transport and deposition model for the region surrounding an individual nanofiber. The interrelationships among processing factors for the transport and deposition are investigated here from a detailed modeling approach that includes the salient physical and chemical phenomena. Solution strategies that couple continuum and atomistic models are used. At the continuum scale, transport dynamics near the nanofiber are described. At the atomic level, molecular dynamics (MD) simulations are used to study the deposition and sputtering mechanisms at the coating surface. Ion kinetic energies and fluxes are passed from the continuum sheath model to the MD simulations. These simulations calculate sputtering and sticking probabilities that in turn are used to calculate parameters for the continuum transport model. The continuum transport model leads to the definition of an evolution equation for the coating-free surface. This equation is solved using boundary perturbation and level set methods to determine the coating morphology as a function of operating conditions

Drugs, money and society (Part II).

Science.gov (United States)

Walley, Tom

2010-09-01

Pharmacoeconomics started as marketing but has developed into a valuable tool in the fuller assessment of drug therapies. Its principles are now widely accepted, and many countries have government-funded agencies with responsibility for its application, most notably the National Institute for Health and Clinical Excellence in England. Many clinical pharmacologists are active in this area, and the discipline itself is part of the clinical pharmacology trainees' curriculum. Further developments will include value-based pricing and its use in cost sharing arrangements between health service and manufacturers.

The Many Meanings of History, Part II

Science.gov (United States)

Szasz, Ferenc M.

1974-01-01

This article contains a collection of quotations about history collected by Professor Szasz. The first part of the collection appeared in the August 1974 issue of "The History Teacher." Readers are invited to send in other definitions they have found. (Author/RM)

Personalized translational epilepsy research - Novel approaches and future perspectives: Part II: Experimental and translational approaches.

Science.gov (United States)

Bauer, Sebastian; van Alphen, Natascha; Becker, Albert; Chiocchetti, Andreas; Deichmann, Ralf; Deller, Thomas; Freiman, Thomas; Freitag, Christine M; Gehrig, Johannes; Hermsen, Anke M; Jedlicka, Peter; Kell, Christian; Klein, Karl Martin; Knake, Susanne; Kullmann, Dimitri M; Liebner, Stefan; Norwood, Braxton A; Omigie, Diana; Plate, Karlheinz; Reif, Andreas; Reif, Philipp S; Reiss, Yvonne; Roeper, Jochen; Ronellenfitsch, Michael W; Schorge, Stephanie; Schratt, Gerhard; Schwarzacher, Stephan W; Steinbach, Joachim P; Strzelczyk, Adam; Triesch, Jochen; Wagner, Marlies; Walker, Matthew C; von Wegner, Frederic; Rosenow, Felix

2017-11-01

Despite the availability of more than 15 new "antiepileptic drugs", the proportion of patients with pharmacoresistant epilepsy has remained constant at about 20-30%. Furthermore, no disease-modifying treatments shown to prevent the development of epilepsy following an initial precipitating brain injury or to reverse established epilepsy have been identified to date. This is likely in part due to the polyetiologic nature of epilepsy, which in turn requires personalized medicine approaches. Recent advances in imaging, pathology, genetics, and epigenetics have led to new pathophysiological concepts and the identification of monogenic causes of epilepsy. In the context of these advances, the First International Symposium on Personalized Translational Epilepsy Research (1st ISymPTER) was held in Frankfurt on September 8, 2016, to discuss novel approaches and future perspectives for personalized translational research. These included new developments and ideas in a range of experimental and clinical areas such as deep phenotyping, quantitative brain imaging, EEG/MEG-based analysis of network dysfunction, tissue-based translational studies, innate immunity mechanisms, microRNA as treatment targets, functional characterization of genetic variants in human cell models and rodent organotypic slice cultures, personalized treatment approaches for monogenic epilepsies, blood-brain barrier dysfunction, therapeutic focal tissue modification, computational modeling for target and biomarker identification, and cost analysis in (monogenic) disease and its treatment. This report on the meeting proceedings is aimed at stimulating much needed investments of time and resources in personalized translational epilepsy research. This Part II includes the experimental and translational approaches and a discussion of the future perspectives, while the diagnostic methods, EEG network analysis, biomarkers, and personalized treatment approaches were addressed in Part I [1]. Copyright © 2017

Topics in Finance: Part II--Financial Analysis

Science.gov (United States)

Laux, Judy

2010-01-01

The second article in a series designed to supplement the introductory financial management course, this essay addresses financial statement analysis, including its impact on stock valuation, disclosure, and managerial behavior. [For "Topics in Finance Part I--Introduction and Stockholder Wealth Maximization," see EJ1060345.

Differential Effect of Solution Conditions on the Conformation of the Actinoporins Sticholysin II and Equinatoxin II

Directory of Open Access Journals (Sweden)

EDSON V.F. FAUTH

2014-12-01

Full Text Available Actinoporins are a family of pore-forming proteins with hemolytic activity. The structural basis for such activity appears to depend on their correct folding. Such folding encompasses a phosphocholine binding site, a tryptophan-rich region and the activity-related N-terminus segment. Additionally, different solution conditions are known to be able to influence the pore formation by actinoporins, as for Sticholysin II (StnII and Equinatoxin II (EqtxII. In this context, the current work intends to characterize the influence of distinct solution conditions in the conformational behavior of these proteins through molecular dynamics (MD simulations. The obtained data offer structural insights into actinoporins dynamics in solution, characterizing its conformational behavior at the atomic level, in accordance with previous experimental data on StnII and EqtxII hemolytic activities.

Disruption Rose Tinted II

OpenAIRE

Livingstone, Andrew

2009-01-01

'Disruption - Rose Tinted II' continues to engage narratives of historical English china as previously explored in the work 'Rose Tinted'. This work engages the sleepy rural idyll which is overlaid with visual contemporary social commentary.

Technical realisation of the VISA-II project, phase I, part IV, IZ-165-o268-1962

International Nuclear Information System (INIS)

Pavicevic, M.

1962-12-01

Project VISA-II is described in IX chapters as follows: introduction, definition of experiments and possibilities of performance; VISA-II channel, new experimental space in the RA reactor; hydraulic tests in the VISA-II channel; measurement of fast neutron and gamma flux in VISA-II channels; measurement of water flow through different VISA-2 irradiation capsules; fabrication of VISA-II capsules; corrosion and heavy water purity problems; safety problems of experiment VISA-2; experimental operation of VISA-II. This chapter VI includes documentation for each type of capsule, review about each experiment within the VISA-II project, the objective and purpose of the experiment as well as experimental device [sr

Long-term solar activity and terrestrial connections. Part II: at the beckon of the sun?

Directory of Open Access Journals (Sweden)

N. D. Diamantides

Full Text Available The research task described herein aims at the structuring of an analytical tool that traces the time course of geophysical phenomena, regional or global, and compares it to the course of long-term solar conditions, long-term meaning decades or a few centuries. The model is based on the premise that since in a last analysis the preponderance of atmospheric, hydrospheric, and, possibly, some aspects of geospheric phenomena are, or have been, powered by energy issuing from the sun - either now or in the past - the long-term behavior of such phenomena is ultimately "connected" to long-term changes occurring in the sun itself. Accordingly, the proposed research firstly derives and models a stable surrogate pattern for the long-term solar activity, secondly introduces a transfer-function algorithm for modeling the connection between the surrogate and terrestrial phenomena viewed as partners in the connection, and thirdly probes the connection outcome for episodic or unanticipated effects that may arise due to the fact that in the present context, the connection, should it exist, is very likely nonlinear. Part I of the study presents the theory of the concept, while Part II demonstrates the concept's pertinence to a number of terrestrial phenomena.

Key words. Solar activity · Kolmogorov algorithm

Comparison of second molar eruption patterns in patients with skeletal Class II and skeletal Class I malocclusions.

Science.gov (United States)

Brin, Ilana; Camasuvi, Semin; Dali, Nasser; Aizenbud, Dror

2006-12-01

The eruptive positions of the second molars in Class I and Class II malocclusions were studied. Pretreatment records of 221 patients with a mean age of 11.3 years were evaluated. About 19% of them had skeletal Class I, 31% had skeletal maxillary Class II, and 50% had skeletal mandibular Class II malocclusions. The mean values of the dental and chronologic ages of the subjects were similar. The eruptive positions in relation to a reference line, the developmental stages of the patients' second molars and dental ages were recorded from the panoramic roentgenograms. The distribution of the various developmental stages in each malocclusion group was similar, and no association between skeletal malocclusion and dental developmental stage of the second molars was encountered. The eruptive position of the maxillary second molars was more occlusal only in the oldest maxillary Class II group, above 12 years of age (P = .02). These results support, in part, previous reports suggesting that the maxillary second molars may erupt earlier in patients with skeletal maxillary Class II malocclusions.

Ultra-violet radiation: hazard in workplaces? (part II)

International Nuclear Information System (INIS)

Mohd Yusof Mohd Ali

2003-01-01

Not many workers are aware that apart from chemicals, physical agents, noise and machines which are known to be hazardous in workplaces, there exist another source of hazard which is equally important to be recognised and respected, that is hazard due to ultrviolet radiation (UV). This is the continuation of part I, which was discussed in the later issue. In this part, hazard of ultraviolet radiation were briefly discused i.e. effects on the skin and the eyes. Other subjects discussed are exposure limits, how to assess the radiation, protection against ultraviolet radiation

Type-II Weyl semimetals.

Science.gov (United States)

Soluyanov, Alexey A; Gresch, Dominik; Wang, Zhijun; Wu, QuanSheng; Troyer, Matthias; Dai, Xi; Bernevig, B Andrei

2015-11-26

Fermions--elementary particles such as electrons--are classified as Dirac, Majorana or Weyl. Majorana and Weyl fermions had not been observed experimentally until the recent discovery of condensed matter systems such as topological superconductors and semimetals, in which they arise as low-energy excitations. Here we propose the existence of a previously overlooked type of Weyl fermion that emerges at the boundary between electron and hole pockets in a new phase of matter. This particle was missed by Weyl because it breaks the stringent Lorentz symmetry in high-energy physics. Lorentz invariance, however, is not present in condensed matter physics, and by generalizing the Dirac equation, we find the new type of Weyl fermion. In particular, whereas Weyl semimetals--materials hosting Weyl fermions--were previously thought to have standard Weyl points with a point-like Fermi surface (which we refer to as type-I), we discover a type-II Weyl point, which is still a protected crossing, but appears at the contact of electron and hole pockets in type-II Weyl semimetals. We predict that WTe2 is an example of a topological semimetal hosting the new particle as a low-energy excitation around such a type-II Weyl point. The existence of type-II Weyl points in WTe2 means that many of its physical properties are very different to those of standard Weyl semimetals with point-like Fermi surfaces.

Solar Type II Radio Bursts and IP Type II Events

Science.gov (United States)

Cane, H. V.; Erickson, W. C.

2005-01-01

We have examined radio data from the WAVES experiment on the Wind spacecraft in conjunction with ground-based data in order to investigate the relationship between the shocks responsible for metric type II radio bursts and the shocks in front of coronal mass ejections (CMEs). The bow shocks of fast, large CMEs are strong interplanetary (IP) shocks, and the associated radio emissions often consist of single broad bands starting below approx. 4 MHz; such emissions were previously called IP type II events. In contrast, metric type II bursts are usually narrowbanded and display two harmonically related bands. In addition to displaying complete dynamic spectra for a number of events, we also analyze the 135 WAVES 1 - 14 MHz slow-drift time periods in 2001-2003. We find that most of the periods contain multiple phenomena, which we divide into three groups: metric type II extensions, IP type II events, and blobs and bands. About half of the WAVES listings include probable extensions of metric type II radio bursts, but in more than half of these events, there were also other slow-drift features. In the 3 yr study period, there were 31 IP type II events; these were associated with the very fastest CMEs. The most common form of activity in the WAVES events, blobs and bands in the frequency range between 1 and 8 MHz, fall below an envelope consistent with the early signatures of an IP type II event. However, most of this activity lasts only a few tens of minutes, whereas IP type II events last for many hours. In this study we find many examples in the radio data of two shock-like phenomena with different characteristics that occur simultaneously in the metric and decametric/hectometric bands, and no clear example of a metric type II burst that extends continuously down in frequency to become an IP type II event. The simplest interpretation is that metric type II bursts, unlike IP type II events, are not caused by shocks driven in front of CMEs.

Failure analysis of leakage on titanium tubes within heat exchangers in a nuclear power plant. Part II: Mechanical degradation

Energy Technology Data Exchange (ETDEWEB)

Gong, Y.; Yang, Z.G. [Department of Materials Science, Fudan University, Shanghai (China); Yuan, J.Z. [Third Qinshan Nuclear Power Co. Ltd., Haiyan, Zhejiang Province (China)

2012-01-15

Serious failure incidents like clogging, quick thinning, and leakage frequently occurred on lots of titanium tubes of heat exchangers in a nuclear power plant in China. In the Part I of the whole failure analysis study with totally two parts, factors mainly involving three kinds of electrochemical corrosions were investigated, including galvanic corrosion, crevice corrosion, and hydrogen-assisted corrosion. In the current Part II, through microscopically analyzing the ruptures on the leaked tubes by scanning electron microscopy (SEM) and energy dispersive spectrometry (EDS), another four causes dominantly lying in the aspect of mechanical degradation were determined - clogging, erosion, mechanical damaging, and fretting. Among them, the erosion effect was the primary one, thus the stresses it exerted on the tube wall were also supplementarily evaluated by finite element method (FEM). Based on the analysis results, the different degradation extents and morphologies by erosion on the tubes when they were clogged by different substances such as seashell, rubber debris, and sediments were compared, and relevant mechanisms were discussed. Finally, countermeasures were put forward as well. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

Notes on the Birds of Central Oaxaca, Part II: Columbidae to Vireonidae

Directory of Open Access Journals (Sweden)

John M. Forcey

2015-06-01

Full Text Available Notas sobre las aves de Oaxaca central, parte II: Columbidae a Vireonidae Se reportan  nuevos datos que amplían y clarifican nuestro conocimiento del estatus y distribución de 70 especies de aves en la región central del Estado de Oaxaca. Las observaciones se realizaron abarcando partes de los distritos de Etla, Ixtlan, Tlacolula, y Zaachila, dentro de un círculo de radio de 35 km alrededor de la Ciudad de Oaxaca. El reporte se basa en observaciones tomadas durante 738 días, comprendidos entre diciembre 1996 y marzo 2002. Los hábitats principalmente visitados fueron pino-encino (incluyendo zonas pequeñas de pino-encino-oyamel y pino-encino mezclado con pastizales, matorral de encino, matorral subtropical, vegetación riparia, y vegetación secundaria, campos agrícolas y otros (incluyendo áreas urbanas, como jardines y parques. Las siguientes especies se reportan por primera vez en la zona: Heliomaster constantii, Tilmatura dupontii, Empidonax flaviventris, Empidonax virescens, Myiarchus crinitus, Myiodynastes luteiventris, Vireo philadelphicus, Vireo olivaceus y Vireo flavoviridis. Además, las siguientes diez especies se han reportado anteriormente una sola vez o solamente en los Conteos Navideños: Caprimulgus ridgwayi (residente,Panyptila sanctihieronymi (residente local, Amazilia cyanocephala (residente local, Amazilia viridifrons, Lamprolaima rhami, Momotus mexicanus (residente en la Sierra Juárez, Sayornis phoebe, Myiozetetes similis (residente, Pachyramphus major (residente y Vireo griseus. Se reportan datos de la reproducción de 25 especies, 18 de las cuales no se habían registrado como reproduciéndose en la zona antes. De estos, 24 se pueden agrupar como reproduciéndose en los meses de abril a julio, y 17 se reproducen en zonas riparias, seis de ellos casi exclusivamente.

Preliminary Guideline for the High Temperature Structure Integrity Assessment Procedure Part II. High Temperature Structural Integrity Assessment

Energy Technology Data Exchange (ETDEWEB)

Lee, Jae Han; Kim, J. B.; Lee, H. Y.; Park, C. G.; Joo, Y. S.; Koo, G. H.; Kim, S. H

2007-02-15

A high temperature structural integrity assessment belongs to the Part II of a whole preliminary guideline for the high temperature structure. The main contents of this guideline are the evaluation procedures of the creep-fatigue crack initiation and growth in high temperature condition, the high temperature LBB evaluation procedure, and the inelastic evaluations of the welded joints in SFR structures. The methodologies for the proper inelastic analysis of an SFR structures in high temperatures are explained and the guidelines of inelastic analysis options using ANSYS and ABAQUS are suggested. In addition, user guidelines for the developed NONSTA code are included. This guidelines need to be continuously revised to improve the applicability to the design and analysis of the SFR structures.

Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (83rd, Phoenix, Arizona, August 9-12, 2000). Miscellaneous, Part II.

Science.gov (United States)

Association for Education in Journalism and Mass Communication.

The Miscellaneous, Part II Section of the proceedings contains the following eight papers: "Academic Letters of Recommendation: Perceived Ethical Implications and Harmful Effects of Exaggeration" (David L. Martinson and Michael Ryan); "It's All about the Information Salience Effects on the Perceptions of News Exemplification"…

Atmospheric fluoride pollution. Part II

Energy Technology Data Exchange (ETDEWEB)

Hasegawa, T; Yamazaki, Y

1969-01-01

In East Osaka, agricultural crops either died or showed poor growth in the neighborhood of a factory producing white cosmetic bottles. Since fluorite was used as a material and there was no damage before the establishment of the factory, it was suspected that fluorine compounds were causing the damage. Quantitative analysis was performed on the agricultural crops and the exhaust gas as well as the dust particles in order to determine the fluorine content. Gas samplers were used to collect the dusts from the surrounding atmosphere. The fluorine content of dust near the factory was about 93 mg per cubic meter per day, and in some parts, as high as 1.54 mq per cubic meter per day. Relatively larger quantities of fluorine were measured at the southwestern and southeastern area of the factory, corresponding to the general wind pattern. Rice and soy beans from the neighborhood of the factory showed concentrations of fluorine and, especially in the leaves of the damaged crops, the concentrations were several hundred times higher than those of the undamaged leaves.

Phosphorylation of rat kidney Na-K pump at Ser938 is required for rapid angiotensin II-dependent stimulation of activity and trafficking in proximal tubule cells.

Science.gov (United States)

Massey, Katherine J; Li, Quanwen; Rossi, Noreen F; Keezer, Susan M; Mattingly, Raymond R; Yingst, Douglas R

2016-02-01

How angiotensin (ANG) II acutely stimulates the Na-K pump in proximal tubules is only partially understood, limiting insight into how ANG II increases blood pressure. First, we tested whether ANG II increases the number of pumps in plasma membranes of native rat proximal tubules under conditions of rapid activation. We found that exposure to 100 pM ANG II for 2 min, which was previously shown to increase affinity of the Na-K pump for Na and stimulate activity threefold, increased the amount of the Na-K pump in plasma membranes of native tubules by 33%. Second, we tested whether previously observed increases in phosphorylation of the Na-K pump at Ser(938) were part of the stimulatory mechanism. These experiments were carried out in opossum kidney cells, cultured proximal tubules stably coexpressing the ANG type 1 (AT1) receptor, and either wild-type or a S938A mutant of rat kidney Na-K pump under conditions found by others to stimulate activity. We found that 10 min of incubation in 10 pM ANG II stimulated activity of wild-type pumps from 2.3 to 3.5 nmol K · mg protein(-1) · min(-1) and increased the amount of the pump in the plasma membrane by 80% but had no effect on cells expressing the S938A mutant. We conclude that acute stimulation of Na-K pump activity in native rat proximal tubules includes increased trafficking to the plasma membrane and that phosphorylation at Ser(938) is part of the mechanism by which ANG II directly stimulates activity and trafficking of the rat kidney Na-K pump in opossum kidney cells.

Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. Part II: Neurochemistry, neurophysiology and neurocognition

Science.gov (United States)

Bandelow, Borwin; Baldwin, David; Abelli, Marianna; Bolea-Alamanac, Blanca; Bourin, Michel; Chamberlain, Samuel R.; Cinosi, Eduardo; Davies, Simon; Domschke, Katharina; Fineberg, Naomi; Grünblatt, Edna; Jarema, Marek; Kim, Yong-Ku; Maron, Eduard; Masdrakis, Vasileios; Mikova, Olya; Nutt, David; Pallanti, Stefano; Pini, Stefano; Ströhle, Andreas; Thibaut, Florence; Vaghix, Matilde M.; Won, Eunsoo; Wedekind, Dirk; Wichniak, Adam; Woolley, Jade; Zwanzger, Peter; Riederer, Peter

2017-01-01

Objective Biomarkers are defined as anatomical, biochemical or physiological traits that are specific to certain disorders or syndromes. The objective of this paper is to summarise the current knowledge of biomarkers for anxiety disorders, obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD). Methods Findings in biomarker research were reviewed by a task force of international experts in the field, consisting of members of the World Federation of Societies for Biological Psychiatry Task Force on Biological Markers and of the European College of Neuropsychopharmacology Anxiety Disorders Research Network. Results The present article (Part II) summarises findings on potential biomarkers in neurochemistry (neurotransmitters such as serotonin, norepinephrine, dopamine or GABA, neuropeptides such as cholecystokinin, neurokinins, atrial natriuretic peptide, or oxytocin, the HPA axis, neurotrophic factors such as NGF and BDNF, immunology and CO2 hypersensitivity), neurophysiology (EEG, heart rate variability) and neurocognition. The accompanying paper (Part I) focuses on neuroimaging and genetics. Conclusions Although at present, none of the putative biomarkers is sufficient and specific as a diagnostic tool, an abundance of high quality research has accumulated that should improve our understanding of the neurobiological causes of anxiety disorders, OCD and PTSD. PMID:27419272

Transition metal complexes with pyrazole-based ligands.Part 29. Reactions of zinc(II and mercury(II thiocyanate with 4-acetyl-3-amino-5-methylpyrazole

Directory of Open Access Journals (Sweden)

KATALIN MÉSZÁROS SZÉCSÉNYI

2009-11-01

Full Text Available The work is concerned with the crystal and molecular structures of zinc(II and mercury(II complexes with 4-acetyl-3-amino-5-methyl-pyrazole (aamp of the coordination formulae [Zn(NCS2(aamp2] and (Haamp2[Hg(SCN4]. The zinc(II complex was obtained by the reaction of a warm methanolic solution of aamp with a mixture of zinc(II nitrate and ammonium thiocyanate, whereas the mercury(II complex was prepared by the reaction of a warm ethanolic solution of aamp and a warm, slightly acidified aqueous solution of [Hg(SCN4]2-. Both complexes have a tetrahedral geometry, which in the case of zinc complex is formed by monodentate coordination of two aamp molecules and two isothiocyanate groups. The Zn(II and Hg(II atoms have significantly deformed coordination geometry. In both crystal structures the pyrazole derivative has a planar form, probably stabilized by an intramolecular N–H···O hydrogen bond. Apart from the X-ray structural analysis, the isolated complexes were characterized by elemental analysis, IR spectroscopy, conductometric measurements and thermal analysis.

Optical photon transport in powdered-phosphor scintillators. Part II. Calculation of single-scattering transport parameters

Energy Technology Data Exchange (ETDEWEB)

Poludniowski, Gavin G. [Joint Department of Physics, Division of Radiotherapy and Imaging, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey SM2 5PT, United Kingdom and Centre for Vision Speech and Signal Processing (CVSSP), Faculty of Engineering and Physical Sciences, University of Surrey, Guildford, Surrey GU2 7XH (United Kingdom); Evans, Philip M. [Centre for Vision Speech and Signal Processing (CVSSP), Faculty of Engineering and Physical Sciences, University of Surrey, Guildford, Surrey GU2 7XH (United Kingdom)

2013-04-15

Purpose: Monte Carlo methods based on the Boltzmann transport equation (BTE) have previously been used to model light transport in powdered-phosphor scintillator screens. Physically motivated guesses or, alternatively, the complexities of Mie theory have been used by some authors to provide the necessary inputs of transport parameters. The purpose of Part II of this work is to: (i) validate predictions of modulation transform function (MTF) using the BTE and calculated values of transport parameters, against experimental data published for two Gd{sub 2}O{sub 2}S:Tb screens; (ii) investigate the impact of size-distribution and emission spectrum on Mie predictions of transport parameters; (iii) suggest simpler and novel geometrical optics-based models for these parameters and compare to the predictions of Mie theory. A computer code package called phsphr is made available that allows the MTF predictions for the screens modeled to be reproduced and novel screens to be simulated. Methods: The transport parameters of interest are the scattering efficiency (Q{sub sct}), absorption efficiency (Q{sub abs}), and the scatter anisotropy (g). Calculations of these parameters are made using the analytic method of Mie theory, for spherical grains of radii 0.1-5.0 {mu}m. The sensitivity of the transport parameters to emission wavelength is investigated using an emission spectrum representative of that of Gd{sub 2}O{sub 2}S:Tb. The impact of a grain-size distribution in the screen on the parameters is investigated using a Gaussian size-distribution ({sigma}= 1%, 5%, or 10% of mean radius). Two simple and novel alternative models to Mie theory are suggested: a geometrical optics and diffraction model (GODM) and an extension of this (GODM+). Comparisons to measured MTF are made for two commercial screens: Lanex Fast Back and Lanex Fast Front (Eastman Kodak Company, Inc.). Results: The Mie theory predictions of transport parameters were shown to be highly sensitive to both grain size

Differences between easy- and difficult-to-mill chickpea (Cicer arietinum L.) genotypes. Part II: protein, lipid and mineral composition.

Science.gov (United States)

Wood, Jennifer A; Knights, Edmund J; Campbell, Grant M; Choct, Mingan

2014-05-01

Part I introduced the concept of easy- and difficult-to-mill chickpea genotypes, the broad chemical composition of their seed fractions and proposed mechanistic explanations for physical differences consistent with observed variation in milling ease. Part II continues this research by delving deeper into the amino acid, fatty acid and mineral components. No association between fatty acid composition and ease of milling was observed. However, particular amino acids and mineral elements were identified that further support roles of lectins, pectins and mineral-facilitated binding in the adhesion of chickpea seed coat and cotyledons. These differences suggest underlying mechanisms that could be exploited by breeding programmes to improve milling performance. This study shows that the content and composition of amino acids, fatty acids and minerals within different chickpea tissues vary with seed type (desi and kabuli) and within desi genotypes in ways that are consistent with physical explanations of how seed structure and properties relate to milling behaviour. © 2013 Society of Chemical Industry.

Neutronics and thermohydraulics of the reactor C.E.N.E. Part II; Analisis neutronico y termohidraulico del reactor C.E.N.E. Parte II

Energy Technology Data Exchange (ETDEWEB)

Caro, R

1976-07-01

In this report the analysis of neutronics thermohydraulics and shielding of the 10 HWt swimming pool reactor C.E.N.E is included. In each of these chapters is given a short description of the theoretical model used, along with the theoretical versus experimental checking carried out, whenever possible, with the reactors JEN-I and JEN-II of Junta de Energia Nuclear. (Author) 11 refs.

Kafka, Borges, and the creation of consciousness, Part II: Borges--a life of letters encompassing everything and nothing.

Science.gov (United States)

Ogden, Thomas H

2009-04-01

The ways in which Kafka and Borges struggled with the creation of consciousness in their lives and in their literary works are explored in this two-part essay. In Part II, a biographical sketch of Jorge Luis Borges is juxtaposed with a close reading of one of his fictions, "The Library of Babel" (1941a). In this story, the universe is an infinite Library, a psychological/literary space comprised of books that contain everything that has ever been or ever will be written. By the end of the story, Borges becomes a character in his own fiction. This development was paralleled in Borges's "real life" as he invented a persona named "Borges," a literary creation that allowed Borges to become a character in a story that was his life. The essay concludes with a comparison of the ways in which Borges and Kafka each used writing as a way of creating his own distinctive form of consciousness, and, in so doing, contributed to the creation of twentieth-century consciousness.

The Tölz Temporal Topography Study: mapping the visual field across the life span. Part II: cognitive factors shaping visual field maps.

Science.gov (United States)

Poggel, Dorothe A; Treutwein, Bernhard; Calmanti, Claudia; Strasburger, Hans

2012-08-01

Part I described the topography of visual performance over the life span. Performance decline was explained only partly by deterioration of the optical apparatus. Part II therefore examines the influence of higher visual and cognitive functions. Visual field maps for 95 healthy observers of static perimetry, double-pulse resolution (DPR), reaction times, and contrast thresholds, were correlated with measures of visual attention (alertness, divided attention, spatial cueing), visual search, and the size of the attention focus. Correlations with the attentional variables were substantial, particularly for variables of temporal processing. DPR thresholds depended on the size of the attention focus. The extraction of cognitive variables from the correlations between topographical variables and participant age substantially reduced those correlations. There is a systematic top-down influence on the aging of visual functions, particularly of temporal variables, that largely explains performance decline and the change of the topography over the life span.

Tratamento sistêmico da psoríase - Parte II: Imunomoduladores biológicos Systemic treatment of psoriasis - Part II: Biologic immunomodulator agents

Directory of Open Access Journals (Sweden)

Lúcia Arruda

2004-08-01

Full Text Available Em continuidade ao capítulo da edição anterior dos Anais Brasileiros de Dermatologia, nesta segunda parte da EMC-D serão discutidas as novas drogas, os imunomoduladores biológicos, que agem em determinadas fases da imunopatogênese da doença, modificando fenotipicamente sua evolução. Também serão discutidos alguns aspectos imunológicos que, atualmente, são responsáveis pelo desencadeamento da doençaAs part of its continued studies of psoriasis, this second part of the Continuing Medical Education in Dermatology segment of the Anais Brasileiros de Dermatologia introduces biological immunomodulators. Also known as "biologics", these drugs act on the immunopathogenetic steps of psoriasis by changing its features and progression. This paper also reviews some of the immunologic aspects of psoriasis.

Designer ligands. Part 15. Synthesis and characterisation of novel Mn(lI), Ni(II) and Zn(II) complexes of 1,10-phenanthroline-derived ligands

CSIR Research Space (South Africa)

Wellington, Kevin W

2009-01-01

Full Text Available Series of manganese(II), nickel(II) and zinc(II) complexes have been prepared using 1,10-phenanthroline-derived ligands, and their coordination geometries have been assigned using infrared data. It is apparent that, depending on the ligand...

An evaluation of highly insulated cold zinc roofs in a moderate humid region - Part II: Corrosion behavior of zinc sheeting

NARCIS (Netherlands)

Zheng, R.; Janssens, A.; Carmeliet, J.; Bogaerts, W.; Hens, H.

2004-01-01

In a previous paper [Zheng et al., Hygrothermal Performance, Part I; Const Building Mater, Vol. 18, Issue 1, pp. 49-59], the hygrothermal performances of four well-insulated cold zinc roofs were evaluated. This paper investigates the corrosion behavior of the zinc sheeting used in the roofs. The

Exploration of Logistics Information Technology (IT) Solutions for the Royal Saudi Naval Force Within the Saudi Naval Expansion Program II (SNEP II)

Science.gov (United States)

2017-12-01

NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA MBA PROFESSIONAL REPORT EXPLORATION OF LOGISTICS INFORMATION TECHNOLOGY (IT) SOLUTIONS FOR THE...INFORMATION TECHNOLOGY (IT) SOLUTIONS FOR THE ROYAL SAUDI NAVAL FORCE WITHIN THE SAUDI NAVAL EXPANSION PROGRAM II (SNEP II) 5. FUNDING NUMBERS 6. AUTHOR(S...Expansion Program II (SNEP II). A part of this program includes upgrading and rebuilding its information technology (IT) infrastructure. The United

Part I. Inviscid, swirling flows and vortex breakdown. Part II. A numerical investigation of the Lundgren turbulence model

International Nuclear Information System (INIS)

Buntine, J.D.

1994-01-01

Part I. A study of the behaviour of an inviscid, swirling fluid is performed. This flow can be described by the Squire-Long equation if the constraints of time-independence and axisymmetry are invoked. The particular case of flow through a diverging pipe is selected and a study is conducted to determine over what range of parameters does a solution exist. The work is performed with a view to understanding how the phenomenon of vortex breakdown develops. Experiments and previous numerical studies have indicated that the flow is sensitive to boundary conditions particularly at the pipe inlet. A open-quotes quasi-cylindricalclose quotes amplification of the Squire-Long equation is compared with the more complete model and shown to be able to account for most of its behaviour. An advantage of this latter representation is the relatively undetailed description of the flow geometry it requires in order to calculate a solution. open-quotes Criticalityclose quotes or the ability of small disturbances to propagate upstream is related to results of the quasi-cylindrical and axisymmetric flow models. This leads to an examination of claims made by researchers such as Benjamin and Hall concerning the interrelationship between open-quotes failureclose quotes of the quasi-cylindrical model and the occurrence of a open-quotes criticalclose quotes flow state. Lundgren developed an analytical model for homogeneous turbulence based on a collection of contracting spiral vortices each embedded in an axisymmetric strain field. Using asymptotic approximations he was able to deduce the Kolmogorov k -5/3 behaviour for inertial scales in the turbulence energy spectrum. Pullin ampersand Saffman have enlarged upon his work to make a number of predictions about the behaviour of turbulence described by the model. This work investigates the model numerically. The first part considers how the flow description compares with numerical simulations using the Navier-Stokes equations

NSLS-II booster timing system

International Nuclear Information System (INIS)

Cheblakov, P.; Karnaev, S.; De Long, J.

2012-01-01

NSLS-II light source includes the main storage ring with beam lines and injection part consisting of 200 MeV linac, a full-energy 3 GeV booster synchrotron and two transport lines. The booster timing system is a part of NSLS-II timing system which uses hardware from MicroResearch Finland: Event Generator (EVG) and Event Receivers (EVRs). The booster timing is based on the events coming from NSLS-II EVG: 'Pre-Injection', 'Injection', 'Pre-Extraction', 'Extraction'. These events are referenced to the selected RF bucket of the storage ring and correspond to the first RF bucket of the booster. EVRs provide triggers both for the injection and the extraction pulse devices. EVRs also provide the timing of booster cycle operation and generation of events for cycle-to-cycle updates of pulsed and ramping parameters, and synchronization of the booster beam instrumentation devices. This paper describes the final design of the booster timing system. The timing system functional diagrams and block diagram are presented. (authors)

NACRE II: an update of the NACRE compilation of charged-particle-induced thermonuclear reaction rates for nuclei with mass number A<16

International Nuclear Information System (INIS)

Xu, Y.; Takahashi, K.; Goriely, S.; Arnould, M.; Ohta, M.; Utsunomiya, H.

2013-01-01

An update of the NACRE compilation [3] is presented. This new compilation, referred to as NACRE II, reports thermonuclear reaction rates for 34 charged-particle induced, two-body exoergic reactions on nuclides with mass number A 6 ≲T⩽10 10 K range. Along with the ‘adopted’ rates, their low and high limits are provided. The new rates are available in electronic form as part of the Brussels Library (BRUSLIB) of nuclear data. The NACRE II rates also supersede the previous NACRE rates in the Nuclear Network Generator (NETGEN) for astrophysics. [ (http://www.astro.ulb.ac.be/databases.html)

Química general II

OpenAIRE

Olba Torrent, Amparo

2018-01-01

El document forma part dels materials docents programats mitjançant l'ajut del Servei de Política Lingüística de la Universitat de València Temes de l'assignatura: Química general II del primer curs del Grau de Química Topics of the course: General Chemistry II in the first year of the Degree in Chemistry

Universal communication part II: channels with memory

OpenAIRE

Lomnitz, Yuval; Feder, Meir

2012-01-01

Consider communication over a channel whose probabilistic model is completely unknown vector-wise and is not assumed to be stationary. Communication over such channels is challenging because knowing the past does not indicate anything about the future. The existence of reliable feedback and common randomness is assumed. In a previous paper it was shown that the Shannon capacity cannot be attained, in general, if the channel is not known. An alternative notion of "capacity" was defined, as the...

Ultrasonic inspection of heavy section steel components: the PISC II final report

International Nuclear Information System (INIS)

Nichols, R.W.; Crutzen, S.

1988-01-01

This Symposium represented the end of the PISC (Programme for Inspection of Steel Components), II Round Robin Test Project, and the book is the final report. The contents are divided into three parts: part 1 contains contributions from the PISC Management Group, part II contains individual contributions, part III contains views of Licensing Authorities. All the twenty three papers presented in the three parts are selected for INIS and indexed separately. (author)

Standing on shaky ground- US patent-eligibility of isolated DNA and genetic diagnostics after AMP v. USPTO - Part II (practical implications & chances for Supreme Court Review)

DEFF Research Database (Denmark)

Minssen, Timo; Nilsson, David

2012-01-01

This is the second part of a four-partite article discussing the US Federal Circuit decision in AMP v. USPTO , also known as the ACLU /Myriad "gene patenting" case ("Myriad"). Part I commenced with a description of the legal framework and an explanation of how the decision relates to the recently...... of the outcome, i.e. the three different opinions of the Federal Circuit judges Lourie, Moore & Bryson who comprised the panel (3). Part II will now continue the tale with a detailed analysis of the decision's practical implications (4), which is followed by a closer look on the chances for an ultimate Supreme...

77 FR 64396 - Order of Succession for HUD Region II

Science.gov (United States)

2012-10-19

... Region II AGENCY: Office of Field Policy and Management, HUD. ACTION: Notice of Order of Succession... Field Offices (Region II). This Order of Succession supersedes all previous Orders of Succession for Region II. DATES: Effective Date: October 9, 2012. FOR FURTHER INFORMATION CONTACT: Lawrence D. Reynolds...

Has the tsunami arrived? Part II.

Science.gov (United States)

Halverson, Dean; Glowac, Wayne

2009-01-01

Healthcare is an industry in the midst of significant change. After years of double-digit cost increases, the system has reached a tipping point. Where once only employers were heard crying out for change, the call is now coming from all levels of American society. The voice that is most important to effect change is the newest--that of the consumer. In part two of our overview of the healthcare tsunami, we hope to offer you some insights and practical ideas on how to improve the return on investment of your marketing. We believe those who work to understand the new market forces and react with insight will not just survive during the tsunami, they will thrive.

Cyclopentane combustion. Part II. Ignition delay measurements and mechanism validation

KAUST Repository

Rachidi, Mariam El

2017-06-12

This study reports cyclopentane ignition delay measurements over a wide range of conditions. The measurements were obtained using two shock tubes and a rapid compression machine, and were used to test a detailed low- and high-temperature mechanism of cyclopentane oxidation that was presented in part I of this study (Al Rashidi et al., 2017). The ignition delay times of cyclopentane/air mixtures were measured over the temperature range of 650–1350K at pressures of 20 and 40atm and equivalence ratios of 0.5, 1.0 and 2.0. The ignition delay times simulated using the detailed chemical kinetic model of cyclopentane oxidation show very good agreement with the experimental measurements, as well as with the cyclopentane ignition and flame speed data available in the literature. The agreement is significantly improved compared to previous models developed and investigated at higher temperatures. Reaction path and sensitivity analyses were performed to provide insights into the ignition-controlling chemistry at low, intermediate and high temperatures. The results obtained in this study confirm that cycloalkanes are less reactive than their non-cyclic counterparts. Moreover, cyclopentane, a high octane number and high octane sensitivity fuel, exhibits minimal low-temperature chemistry and is considerably less reactive than cyclohexane. This study presents the first experimental low-temperature ignition delay data of cyclopentane, a potential fuel-blending component of particular interest due to its desirable antiknock characteristics.

Cyclopentane combustion. Part II. Ignition delay measurements and mechanism validation

KAUST Repository

Rachidi, Mariam El; Má rmol, Juan C.; Banyon, Colin; Sajid, Muhammad Bilal; Mehl, Marco; Pitz, William J.; Mohamed, Samah; Alfazazi, Adamu; Lu, Tianfeng; Curran, Henry J.; Farooq, Aamir; Sarathy, Mani

2017-01-01

This study reports cyclopentane ignition delay measurements over a wide range of conditions. The measurements were obtained using two shock tubes and a rapid compression machine, and were used to test a detailed low- and high-temperature mechanism of cyclopentane oxidation that was presented in part I of this study (Al Rashidi et al., 2017). The ignition delay times of cyclopentane/air mixtures were measured over the temperature range of 650–1350K at pressures of 20 and 40atm and equivalence ratios of 0.5, 1.0 and 2.0. The ignition delay times simulated using the detailed chemical kinetic model of cyclopentane oxidation show very good agreement with the experimental measurements, as well as with the cyclopentane ignition and flame speed data available in the literature. The agreement is significantly improved compared to previous models developed and investigated at higher temperatures. Reaction path and sensitivity analyses were performed to provide insights into the ignition-controlling chemistry at low, intermediate and high temperatures. The results obtained in this study confirm that cycloalkanes are less reactive than their non-cyclic counterparts. Moreover, cyclopentane, a high octane number and high octane sensitivity fuel, exhibits minimal low-temperature chemistry and is considerably less reactive than cyclohexane. This study presents the first experimental low-temperature ignition delay data of cyclopentane, a potential fuel-blending component of particular interest due to its desirable antiknock characteristics.

Conference on the Trend in Income Inequality in the U.S. Part I, Trends in Inequality of Well-Offness in the United States since World War II. Part 2, Conference Overview: Conceptual Issues, Data Issues, and Policy Implications

Science.gov (United States)

Taussig, Michael K.; Danziger, Sheldon

The first part of this document summarizes the current state of knowledge on trends in inequality of economic well-being in the United States since World War II. It surveys alternative answers to the often asked question: Has inequality in the U.S. increased, decreased, or remained roughly the same over a period of time? Intelligent laymen, and…

The evolution of myiasis in humans and other animals in the Old and New Worlds (part II): biological and life-history studies.

Science.gov (United States)

Stevens, Jamie R; Wallman, James F; Otranto, Domenico; Wall, Richard; Pape, Thomas

2006-04-01

Myiasis, which is the dipteran parasitism of living vertebrates, occurs in several forms - ranging from benign to fatal, opportunistic to obligate - and seems to have evolved through two distinct routes: saprophagous and sanguinivorous. However, the convergent evolution of morphological and life-history traits seems to have had a major role in confusing the overall picture of how myiasis evolved and this simplistic division is further complicated by the existence of both ectoparasitic and endoparasitic species of myiasis-causing Diptera, the evolutionary affinities of which remain to be resolved. As discussed in part I of this review, if we are to elucidate how the different forms of parasitism arose, it is essential to separate the evolution of the various groups of myiasis-causing flies from the evolution of the myiasis habit per se. Accordingly, whereas we focused on recent landmark phylogenetics studies in part I, we use this framework to analyse relevant biochemical, immunological, behavioural, biogeographical and fossil evidence to elucidate the evolution of myiasis in part II.

Continuum theory of the mixed-state and surface Joule effects in type-II superconductors

International Nuclear Information System (INIS)

Hocquet, T.; Mathieu, P.; Simon, Y.

1992-01-01

A phenomenological theory of vortex motion, where the mixed state is regarded as a continuum, has been proposed by two of the authors in a short previous letter. Its outlines are recalled in this paper with further comments and arguments; in particular the basic equations and their implications are discussed at some length. This theory leads to a model of pinning, from which we argue that critical currents I c , in soft type-II samples of standard bulk homogeneity, should be governed essentially by surface defects. I c is interpreted as a physically well-defined part of the total transport current I, which is flowing over a small depth close to the surface. Thus, on the scale of an ordinary sample, this part of the transport current is superficial, the remaining part I-I c being uniformly distributed over the cross section. Coherently, an analysis of the dissipation in such samples predicts that the part VI c of the total Joule effect VI must arise as surface heat sources, while the Joule effect V(I-I c ), usually associated with the steady viscous flow of vortices, is uniformly distributed in the bulk. As a proof, we present a method, using second-sound acoustics, to detect and separate surface and volume heat sources. Experimental results give clear evidence of a surface Joule effect, and support the validity of our model of surface pinning in soft materials

Part I. Mechanisms of injury associated with extracorporeal shock wave lithotripsy; Part II. Exsolution of volatiles

Science.gov (United States)

Howard, Danny Dwayne

Part I - Shock waves are focused in extracorporeal shock wave lithotripsy (ESWL) machines to strengths sufficient to fracture kidney stones. Substantial side effects-most of them acute-have resulted from this procedure, including injury to soft tissue. The focusing of shock waves through various layers of tissue is a complex process which stimulates many bio-mechano-chemical responses.This thesis presents results of an in vitro study of the initial mechanical stimulus. Planar nitrocellulose membranes of order 10 um thick were used as models of thin tissue structures. Two modes of failure were recorded: Failure due to cavitation collapsing on or near the membranes, and failure induced by altering the structure of shock waves. Tests were done in water at and around F2 to characterize the extent of cavitation damage, and was found to be confined within the focal region, 1.2 cm along the axis of focus.Scattering media were used to simulate the effects of acoustic nonuniformity of tissue and to alter the structure of focusing shock waves. 40 um diameter (average) hollow glass spheres were added to ethylene glycol, glycerine and castor oil to vary the properties of the scattering media. Multiple layer samples of various types of phantom tissue were tested in degassed castor oil to gauge the validity of the scattering media. The scattering media and tissue samples increased the rise time decreased strain rate in a similar fashion. Membranes were damaged by the decreased strain rate and accumulated effects of the altered structure: After about 20 or so shocks immersed in the scattering media and after about 100 shocks behind the tissue samples. The mode of failure was tearing with multiple tears in some cases from about .1 cm to about 3 cm depending of the number of shocks and membrane thickness.Part II - This work examines the exsolution of volatiles-carbon dioxide from water-in a cylindrical test cell under different pressure conditions. Water was supersaturated with

Stochastic theory of nonequilibrium steady states. Part II: Applications in chemical biophysics

International Nuclear Information System (INIS)

Ge Hao; Qian Min; Qian Hong

2012-01-01

The mathematical theory of nonequilibrium steady state (NESS) has a natural application in open biochemical systems which have sustained source(s) and sink(s) in terms of a difference in their chemical potentials. After a brief introduction in Section , in Part II of this review, we present the widely studied biochemical enzyme kinetics, the workhorse of biochemical dynamic modeling, in terms of the theory of NESS (Section ). We then show that several phenomena in enzyme kinetics, including a newly discovered activation–inhibition switching (Section ) and the well-known non-Michaelis–Menten-cooperativity (Section ) and kinetic proofreading (Section ), are all consequences of the NESS of driven biochemical systems with associated cycle fluxes. Section is focused on nonlinear and nonequilibrium systems of biochemical reactions. We use the phosphorylation–dephosphorylation cycle (PdPC), one of the most important biochemical signaling networks, as an example (Section ). It starts with a brief introduction of the Delbrück–Gillespie process approach to mesoscopic biochemical kinetics (Sections ). We shall discuss the zeroth-order ultrasensitivity of PdPC in terms of a new concept — the temporal cooperativity (Sections ), as well as PdPC with feedback which leads to biochemical nonlinear bistability (Section ). Also, both are nonequilibrium phenomena. PdPC with a nonlinear feedback is kinetically isomorphic to a self-regulating gene expression network, hence the theory of NESS discussed here could have wide applications to many other biochemical systems.

A-Part Gel, an adhesion prophylaxis for abdominal surgery: a randomized controlled phase I-II safety study [NCT00646412].

Science.gov (United States)

Lang, Reinhold; Baumann, Petra; Schmoor, Claudia; Odermatt, Erich K; Wente, Moritz N; Jauch, Karl-Walter

2015-01-01

Intra-abdominal surgical intervention can cause the development of intra-peritoneal adhesions. To reduce this problem, different agents have been tested to minimize abdominal adhesions; however, the optimal adhesion prophylaxis has not been found so far. Therefore, the A-Part(®) Gel was developed as a barrier to diminish postsurgical adhesions; the aim of this randomized controlled study was a first evaluation of its safety and efficacy. In this prospective, controlled, randomized, patient-blinded, monocenter phase I-II study, 62 patients received either the hydrogel A-Part-Gel(®) as an anti-adhesive barrier or were untreated after primary elective median laparotomy. Primary endpoint was the occurrence of peritonitis and/or wound healing impairment 28 ± 10 days postoperatively. As secondary endpoints anastomotic leakage until 28 days after surgery, adverse events and adhesions were assessed until 3 months postoperatively. A lower rate of wound healing impairment and/or peritonitis was observed in the A-Part Gel(®) group compared to the control group: (6.5 vs. 13.8 %). The difference between the two groups was -7.3%, 90 % confidence interval [-20.1, 5.4 %]. Both treatment groups showed similar frequency of anastomotic leakage but incidence of adverse events and serious adverse events were slightly lower in the A-Part Gel(®) group compared to the control. Adhesion rates were comparable in both groups. A-Part Gel(®) is safe as an adhesion prophylaxis after abdominal wall surgery but no reduction of postoperative peritoneal adhesion could be found in comparison to the control group. This may at least in part be due to the small sample size as well as to the incomplete coverage of the incision due to the used application. NCT00646412.

14 CFR 21.303 - Replacement and modification parts.

Science.gov (United States)

2010-01-01

... conforms to the drawings in the design; and (4) That the fabrication processes, construction, and assembly... AIRCRAFT CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS Approval of Materials, Parts, Processes, and... the configuration of the part; and (ii) Information on dimensions, materials, and processes necessary...

The X-ray energy response of silicon. Part A. Theory

International Nuclear Information System (INIS)

Fraser, G.W.; Abbey, A.F.; Holland, A.; McCarthy, K.; Owens, A.; Wells, A.

1994-01-01

In this, the first part of a two-part study of the interaction of soft X-rays with silicon, motivated by the calibration requirements of CCD imaging spectrometers in astronomy, we describe a Monte Carlo model of X-ray energy loss whose products are the energy- and temperature-dependences of (i) W, the average energy required to create an electron-hole pair, and (ii) the Fano factor F. W and F have invariably been treated as material constants in previous analyses of Si X-ray detector performance. We show that in fact, at constant detector temperature T, W is an increasing function of X-ray energy for E -4 K -1 at a typical CCD operating temperature of 170 K. We discuss the practical implications of these results. Finally, we describe our separate calculations of the near-edge variation of CCD quantum detection efficiency arising from silicon K-shell Extended X-ray Absorption Fine Structure (EXAFS). ((orig.))

EBR-II: search for the lost subassembly

International Nuclear Information System (INIS)

King, R.W.; Buschman, H.W.; Poloncsik, J.; Remsburg, J.S.; Sine, H.W.

1983-01-01

Experimental Breeder Reactor II (EBR-II) has been operating for nearly 20 years as part of the foundation of the US Department of Energy's LMFBR development program. During that time, the EBR-II fuel-handling system has performed extremely well, especially considering the conditions under which much of the system operates and the reliability required to maintain the high plant factor routinely demonstrated by EBR-II. Since EBR-II is a pool-type reactor, much of the fuel handling is done remotely within the sodium-filled primary tank at 371 0 C. Activities involved in locating a misplaced fuel subassembly in the primary tank are described

Neuroscience in Nazi Europe Part III

DEFF Research Database (Denmark)

Zeidman, Lawrence A; Kondziella, Daniel

2012-01-01

In Part I, neuroscience collaborators with the Nazis were discussed, and in Part II, neuroscience resistors were discussed. In Part III, we discuss the tragedy regarding european neuroscientists who became victims of the Nazi onslaught on “non-Aryan” doctors. Some of these unfortunate...... of neuroscience, we pay homage and do not allow humanity to forget, lest this dark period in history ever repeat itself....

The Relationship between Mg ii Broad Emission and Quasar Inclination Angle

Directory of Open Access Journals (Sweden)

Conor Wildy

2017-11-01

Full Text Available Several observed spectral properties of quasars are believed to be influenced by quasar orientation. In this investigation we examine the effect of orientation on the Mg ii line located at 2,798 Å in a sample of 36 radio-loud quasars, with orientation angles having been obtained in a previous study using radio observations. We find no significant relationship between orientation angle and either Mg ii line full-width at half-maximum or equivalent width. The lack of correlation with inclination angle contradicts previous studies which also use radio data as a proxy for inclination angle and suggests the Mg ii emission region does not occupy a disk-like geometry. The lack of correlation with Mg ii equivalent width, however, is reported in at least one previous study. Although the significance is not very strong (86%, there is a possible negative relationship between inclination angle and Fe ii strength which, if true, could explain the Fe ii anti-correlation with [O iii] strength associated with Eigenvector 1. Interestingly, there are objects having almost edge-on inclinations while still exhibiting broad lines. This could be explained by a torus which is either clumpy (allowing sight lines to the central engine or mis-aligned with the accretion disk.

The Relationship between Mg ii Broad Emission and Quasar Inclination Angle

Energy Technology Data Exchange (ETDEWEB)

Wildy, Conor; Czerny, Bozena, E-mail: wildy@cft.edu.pl [Center for Theoretical Physics, Polish Academy of Sciences, Warsaw (Poland)

2017-11-14

Several observed spectral properties of quasars are believed to be influenced by quasar orientation. In this investigation we examine the effect of orientation on the Mg ii line located at 2,798 Å in a sample of 36 radio-loud quasars, with orientation angles having been obtained in a previous study using radio observations. We find no significant relationship between orientation angle and either Mg ii line full-width at half-maximum or equivalent width. The lack of correlation with inclination angle contradicts previous studies which also use radio data as a proxy for inclination angle and suggests the Mg ii emission region does not occupy a disk-like geometry. The lack of correlation with Mg ii equivalent width, however, is reported in at least one previous study. Although the significance is not very strong (86%), there is a possible negative relationship between inclination angle and Fe ii strength which, if true, could explain the Fe ii anti-correlation with [O iii] strength associated with Eigenvector 1. Interestingly, there are objects having almost edge-on inclinations while still exhibiting broad lines. This could be explained by a torus which is either clumpy (allowing sight lines to the central engine) or mis-aligned with the accretion disk.

The Influence of Injection Pockets on the Performance of Tilting-Pad Thrust Bearings - Part II: Comparison Between Theory and Experiment

DEFF Research Database (Denmark)

Heinrichson, Niels; Fuerst, Axel; Santos, Ilmar

2007-01-01

This is Part II of a two-part series of papers describing the effects of high-pressure injection pockets on the operating conditions of tilting-pad thrust bearings. The paper has two main objectives. One is an experimental investigation of the influence of an oil injection pocket on the pressure...... and without oil injection) on the pressure distribution and oil film thickness. Measurements of the distribution of pressure and oil film thickness are presented for tilting-pad thrust bearing pads of approx. 100 cm^2 surface area. Two pads are measured in a laboratory test rig at loads of approx. 1.5 MPa...... and approx. 4.0 MPa and velocities of up to 33 m/s. One pad has a plain surface. The other pad has a conical injection pocket at the pivot point and a leading-edge taper. The measurements are compared to theoretical values obtained using a three-dimensional thermoelastohydrodynamic (TEHD) numerical model...

Exoskeletal meal assistance system (EMAS II) for progressive muscle dystrophy patient.

Science.gov (United States)

Hasegawa, Yasuhisa; Oura, Saori

2011-01-01

This paper introduces a 4-DOFs exoskeletal meal assistance system (EMAS II) for progressive muscle dystrophy patient. It is generally better for the patient to use his/her hands by himself in daily life because active works maintain level of residual functions, health and initiative of him/her. The EMAS II that has a new joystick-type user interface device and three-DOFs on a shoulder part is enhanced for an easier operation and more comfortable support on eating, as the succeeding model of the previous system that has two-DOFs on a shoulder. In order to control the 4-DOFs system by the simple user interface device, the EMAS II simulates upper limb motion patterns of a healthy person. The motion patterns are modeled by extracting correlations between the height of a user's wrist joint and that of the user's elbow joint at the table. Moreover, the EMAS II automatically brings user's hand up to his/her mouth or back to a table when he/she pushes a preset switch on the interface device. Therefore a user has only to control a position of his/her wrist to pick or scoop foods and then flip the switch to start automatic mode, while a height of the elbow joint is automatically controlled by the EMAS II itself. The results of experiments, where a healthy subject regarded as a muscle dystrophy patient eats a meal with EMAS II, show that the subject finished her meal in a natural way in 18 minutes 40 seconds which was within a recommended time of 30 minutes. © 2011 IEEE

Development of Intelligent Database Program for PSI/ISI Data Management of Nuclear Power Plant (Part II)

International Nuclear Information System (INIS)

Park, Un Su; Park, Ik Keun; Um, Byong Guk; Lee, Jong Po; Han, Chi Hyun

2000-01-01

In a previous paper, we have discussed the intelligent Windows 95-based data management program(IDPIN) which was developed for effective and efficient management of large amounts of pre-/in-service inspection(PSI/ISI) data of Kori nuclear power plants. The IDPIN program enables the prompt extraction of previously conducted PSI/ISI conditions and results so that the time-consuming data management, painstaking data processing and analysis of the past are avoided. In this study, the intelligent Windows based data management program(WS-IDPIN) has been developed as an effective data management of PSI/ISI data for the Wolsong nuclear power plants. The WS-IDPIN program includes the modules of comprehensive management and analysis of PSI/ISI results, statistical reliability assessment program of PSI/ISI results(depth and length sizing performance etc), standardization of UT report form and computerization of UT results. In addition, the program can be further developed as a unique PSI/ISI data management expert system which can be part of the PSI/ISI total support system for Korean nuclear power plants

Development of industry processes simulators. Part II (continuous casting); Desarrollo de simuladores para procesos industriales. Parte II (Colada continua)

Energy Technology Data Exchange (ETDEWEB)

Ramirez, A.; Mosqueda, A.; Sauce, V.; Morales, R.; Ramos, A.; Solario, G.

2006-07-01

The understanding of steel thermal behavior is very important in order to take care the quality of the products like billets and slabs due to these; this work shows the joint of a subroutine to simulate the heat transfer conditions during the continuous casting process to the model for simulating the process described by the present authors in a previous work; the result is the temperature profiles and surface temperature graphics of the steel, then they are compared with data carried out or real operating conditions. (Author). 15 refs.

Developing a research agenda for reducing the stigma of addictions, part II: Lessons from the mental health stigma literature.

Science.gov (United States)

Corrigan, Patrick W; Schomerus, Georg; Shuman, Valery; Kraus, Dana; Perlick, Debbie; Harnish, Autumn; Kulesza, Magdalena; Kane-Willis, Kathleen; Qin, Sang; Smelson, David

2017-01-01

Although advocates and providers identify stigma as a major factor in confounding the recovery of people with SUDs, research on addiction stigma is lacking, especially when compared to the substantive literature examining the stigma of mental illness. A comprehensive review of the stigma literature that yielded empirically supported concepts and methods from the mental health arena was contrasted with the much smaller and mostly descriptive findings from the addiction field. In Part I of this two part paper (American Journal of Addictions, Vol 26, pages 59-66, this issue), constructs and methods from the mental health stigma literature were used to summarize research that seeks to understand the phenomena of addiction stigma. In Paper II, we use this summary, as well as the extensive literature on mental illness stigma change, to outline a research program to develop and evaluate strategies meant to diminish impact on public and self-stigma (eg, education and contact). The paper ends with recommendations for next steps in addiction stigma research. (Am J Addict 2017;26:67-74). © 2016 American Academy of Addiction Psychiatry.

Classifying previously undefined days from eleven years of aerosol-particle-size distribution data from the SMEAR II station, Hyytiälä, Finland

Directory of Open Access Journals (Sweden)

S. Buenrostro Mazon

2009-01-01

Full Text Available Studies of secondary aerosol-particle formation depend on identifying days in which new particle formation occurs and, by comparing them to days with no signs of particle formation, identifying the conditions favourable for formation. Continuous aerosol size distribution data has been collected at the SMEAR II station in a boreal forest in Hyytiälä, Finland, since 1996, making it the longest time series of aerosol size distributions available worldwide. In previous studies, the data have been classified as particle-formation event, nonevent, and undefined days, with almost 40% of the dataset classified as undefined. In the present study, eleven years (1996–2006 of undefined days (1630 days were reanalyzed and subdivided into three new classes: failed events (37% of all previously undefined days, ultrafine-mode concentration peaks (34%, and pollution-related concentration peaks (19%. Unclassified days (10% comprised the rest of the previously undefined days. The failed events were further subdivided into tail events (21%, where a tail of a formation event presumed to be advected to Hyytiälä from elsewhere, and quasi events (16% where new particles appeared at sizes 3–10 nm, but showed unclear growth, the mode persisted for less than an hour, or both. The ultrafine concentration peaks days were further subdivided into nucleation-mode peaks (24% and Aitken-mode peaks (10%, depending on the size range where the particles occurred. The mean annual distribution of the failed events has a maximum during summer, whereas the two peak classes have maxima during winter. The summer minimum previously found in the seasonal distribution of event days partially offsets a summer maximum in failed-event days. Daily-mean relative humidity and condensation sink values are useful in discriminating the new classes from each other. Specifically, event days had low values of relative humidity and condensation sink relative to nonevent days. Failed-event days

Towards multi-resolution global climate modeling with ECHAM6-FESOM. Part II: climate variability

Science.gov (United States)

Rackow, T.; Goessling, H. F.; Jung, T.; Sidorenko, D.; Semmler, T.; Barbi, D.; Handorf, D.

2018-04-01

This study forms part II of two papers describing ECHAM6-FESOM, a newly established global climate model with a unique multi-resolution sea ice-ocean component. While part I deals with the model description and the mean climate state, here we examine the internal climate variability of the model under constant present-day (1990) conditions. We (1) assess the internal variations in the model in terms of objective variability performance indices, (2) analyze variations in global mean surface temperature and put them in context to variations in the observed record, with particular emphasis on the recent warming slowdown, (3) analyze and validate the most common atmospheric and oceanic variability patterns, (4) diagnose the potential predictability of various climate indices, and (5) put the multi-resolution approach to the test by comparing two setups that differ only in oceanic resolution in the equatorial belt, where one ocean mesh keeps the coarse 1° resolution applied in the adjacent open-ocean regions and the other mesh is gradually refined to 0.25°. Objective variability performance indices show that, in the considered setups, ECHAM6-FESOM performs overall favourably compared to five well-established climate models. Internal variations of the global mean surface temperature in the model are consistent with observed fluctuations and suggest that the recent warming slowdown can be explained as a once-in-one-hundred-years event caused by internal climate variability; periods of strong cooling in the model (`hiatus' analogs) are mainly associated with ENSO-related variability and to a lesser degree also to PDO shifts, with the AMO playing a minor role. Common atmospheric and oceanic variability patterns are simulated largely consistent with their real counterparts. Typical deficits also found in other models at similar resolutions remain, in particular too weak non-seasonal variability of SSTs over large parts of the ocean and episodic periods of almost absent

STARFIRE-II studies. Summary

International Nuclear Information System (INIS)

Baker, C.C.; Brooks, J.N.; Ehst, D.A.; Smith, D.L.; Sze, D.K.

1985-01-01

The US Department of Energy's Office of Fusion Energy has initiated several studies during FY-1985 called Tokamak Power System Studies (TPSS). The TPSS is being carried out by several laboratories, universities and industry with the general objective of developing innovative physics and technology concepts to improve the commercial attractiveness of tokamak power reactors. The effort of Argonne National Laboratory, entitled STARFIRE-II, is an effort to update and improve STARFIRE, which was the last comprehensive conceptual design study in the US of a commercial tokamak power plant. The STARFIRE-II effort has developed a number of goals in order to improve fusion commercial power plants based in part on several recent studies. The primary goals for STARFIRE-II are listed

Angiotensin II induces calcium/calcineurin signaling and podocyte injury by downregulating microRNA-30 family members.

Science.gov (United States)

Zhao, Yue; Wu, Junnan; Zhang, Mingchao; Zhou, Minlin; Xu, Feng; Zhu, Xiaodong; Zhou, Xianguang; Lang, Yue; Yang, Fan; Yun, Shifeng; Shi, Shaolin; Liu, Zhihong

2017-08-01

Angiotensin II (AngII) is capable of inducing calcium/calcineurin signaling and podocyte injury; however, the precise underlying mechanism is not well understood. Because we have previously demonstrated that microRNA-30s (miR-30s) inhibit calcium/calcineurin signaling in podocytes, we hypothesize that AngII may induce podocyte injury by downregulating miR-30s and thereby activating calcium/calcineurin signaling. To test this hypothesis, we used an AngII-induced podocyte injury mouse model. The mice were treated with AngII via infusion for 28 days, which resulted in hypertension, albuminuria, and glomerular damage. AngII treatment also resulted in a significant reduction of miR-30s and upregulation of calcium/calcineurin signaling components, including TRPC6, PPP3CA, PPP3CB, PPP3R1, and NFATC3, which are the known targets of miR-30s in podocytes. The delivery of miR-30a-expressing lentivirus to the podocytes on day 14 of the infusion ameliorated the AngII-induced podocyte and glomerular injury and attenuated the upregulation of the calcium/calcineurin signaling components. Similarly, treatment with losartan, which is an AngII receptor blocker, also prevented AngII-induced podocyte injury and calcium/calcineurin signaling activation. Notably, losartan was found to sustain miR-30 levels during AngII treatment both in vivo and in vitro. In conclusion, the effect of AngII on podocytes is in part mediated by miR-30s through calcium/calcineurin signaling, a novel mechanism underlying AngII-induced podocyte injury. • AngII infusion resulted in downregulation of miR-30s in podocytes. • Exogenous miR-30a delivery mitigated the glomerular and podocyte injuries induced by AngII. • Both miR-30a and losartan prevented AngII-induced activation of calcium-calcineurin signaling.

EBR-II high-ramp transients under computer control

International Nuclear Information System (INIS)

Forrester, R.J.; Larson, H.A.; Christensen, L.J.; Booty, W.F.; Dean, E.M.

1983-01-01

During reactor run 122, EBR-II was subjected to 13 computer-controlled overpower transients at ramps of 4 MWt/s to qualify the facility and fuel for transient testing of LMFBR oxide fuels as part of the EBR-II operational-reliability-testing (ORT) program. A computer-controlled automatic control-rod drive system (ACRDS), designed by EBR-II personnel, permitted automatic control on demand power during the transients

A thermoelectric power generating heat exchanger: Part II – Numerical modeling and optimization

International Nuclear Information System (INIS)

Sarhadi, Ali; Bjørk, Rasmus; Lindeburg, Niels; Viereck, Peter; Pryds, Nini

2016-01-01

Highlights: • A comprehensive model was developed to optimize the integrated TEG-heat exchanger. • The developed model was validated with the experimental data. • The effect of using different interface materials on the output power was assessed. • The influence of TEG arrangement on the power production was investigated. • Optimized geometrical parameters and proper interface materials were suggested. - Abstract: In Part I of this study, the performance of an experimental integrated thermoelectric generator (TEG)-heat exchanger was presented. In the current study, Part II, the obtained experimental results are compared with those predicted by a finite element (FE) model. In the simulation of the integrated TEG-heat exchanger, the thermal contact resistance between the TEG and the heat exchanger is modeled assuming either an ideal thermal contact or using a combined Cooper–Mikic–Yovanovich (CMY) and parallel plate gap formulation, which takes into account the contact pressure, roughness and hardness of the interface surfaces as well as the air gap thermal resistance at the interface. The combined CMY and parallel plate gap model is then further developed to simulate the thermal contact resistance for the case of an interface material. The numerical results show good agreement with the experimental data with an average deviation of 17% for the case without interface material and 12% in the case of including additional material at the interfaces. The model is then employed to evaluate the power production of the integrated system using different interface materials, including graphite, aluminum (Al), tin (Sn) and lead (Pb) in a form of thin foils. The numerical results show that lead foil at the interface has the best performance, with an improvement in power production of 34% compared to graphite foil. Finally, the model predicts that for a certain flow rate, increasing the parallel TEG channels for the integrated systems with 4, 8, and 12 TEGs

Start II, red ink, and Boris Yeltsin

International Nuclear Information System (INIS)

Arbatov, A.

1993-01-01

Apart from the vulnerability implied by the START II treaty, it will bear the burden of the general political opposition to the Yeltsin administration. START II will be seen as part of an overall Yeltsin-Andrei Kozyrev foreign policy that is under fire for selling out Russian national interests in Yugoslavia, the Persian Gulf, and elsewhere. This article discusses public opinion concerning START II, the cost of its implementation, and the general purpose of the treaty

The sociogeometry of inequality: Part II

Science.gov (United States)

Eliazar, Iddo

2015-05-01

The study of socioeconomic inequality is of prime economic and social importance, and the key quantitative gauges of socioeconomic inequality are Lorenz curves and inequality indices - the most notable of the latter being the popular Gini index. In this series of papers we present a sociogeometric framework to the study of socioeconomic inequality. In this part we focus on the gap between the rich and the poor, which is quantified by gauges termed disparity curves. We shift from disparity curves to disparity sets, define inequality indices in terms of disparity sets, and introduce and explore a collection of distance-based and width-based inequality indices stemming from the geometry of disparity sets. We conclude with mean-absolute-deviation (MAD) representations of the inequality indices established in this series of papers, and with a comparison of these indices to the popular Gini index.

Part I. A study of the decays D → Kππeν and D → K*πeν. Part II. SLD Cherenkov Ring Imaging Detector development

International Nuclear Information System (INIS)

Huber, J.S.

1992-01-01

A thesis in two independent halves. Part I. A search for the exclusive semileptonic decay modes D + → bar K ππ + ν e and D + → bar K * πe + ν e are presented using data from the Fermi-lab photoproduction experiment E691. With good sensitivity, the author observes no signals in the channels D + → K - π + π degrees e + ν e and D + → bar K degrees π + π - e + ν e , and set upper limits that represent only a small fraction of the inclusive semileptonic branching ration. The experiment was conducted at the Fermi-lab tagged Photon Laboratory, using a large acceptance spectrometer with silicon microvertex detector to extract a large, clean charm sample. Part II. The physics, design, and results of the Stanford Large Detector (SLD) Cherenkov Ring Imaging Detector (CRID) are described. The physics motivation and performance for the SLD CRID, the principles of Cherenkov detection, and a description of the SLD CRID are combined with a detailed description of the production and testing of the mirrors. In addition, results from the engineering run and cosmic ray tests demonstrate the current status of the system

Resolution of the Task A-11 reactor-vessel materials-toughness safety issue. Part I. Main report. Part II. Staff responses to public comments, and Appendices A and B

International Nuclear Information System (INIS)

Johnson, R.

1982-10-01

This report provides the NRC position with respect to the reactor pressure vessel safety analysis required according to the rules given in the Code of Federal Regulations, Title 10 (10 CFR). An analysis is required whenever neutron irradiation reduces the Charpy V-notch upper shelf energy level in the vessel steel to 50 ft-lb or less. Task A-11 was needed because the available engineering methodology for such an analysis utilized linear elastic fracture mechanics principles, which could not fully account for the plastic deformation or stable crack extension expected at upper shelf temperatures. The Task A-11 goal was to develop an elastic-plastic fracture mechanics methodology, applicable to the beltline region of a pressurized water reactor vessel, which could be used in the required safety analysis. The goal was achieved with the help of a team of recognized experts. Part I of this volume contains the For Comment NUREG-0744, originally published in September 1981 and edited to accommodate comments from the public and the NRC staff. Edited segments are noted by vertical marginal lines. Part II of this volume contains the staff's responses to, and resolution of, the public comments received

Human T-cell leukemia virus types I and II exhibit different DNase I protection patterns

International Nuclear Information System (INIS)

Altman, R.; Harrich, D.; Garcia, J.A.; Gaynor, R.B.

1988-01-01

Human T-cell leukemia virus types I (HTLV-I) and II (HTLV-II) are human retroviruses which normally infect T-lymphoid cells. HTLV-I infection is associated with adult T-cell leukemia-lymphoma, and HTLV-II is associated with an indolent form of hairy-cell leukemia. To identify potential transcriptional regulatory elements of these two related human retroviruses, the authors performed DNase I footprinting of both the HTLV-I and HTLV-II long terminal repeats (LTRs) by using extracts prepared from uninfected T cells, HTLV-I and HTLV-II transformed T cells, and HeLa cells. Five regions of the HTLV-I LTR and three regions of the HTLV-II LTR showed protection by DNase I footprinting. All three of the 21-base-pair repeats previously shown to be important in HTLV transcriptional regulation were protected in the HTLV-I LTR, whereas only one of these repeats was protected in the HTLV-II LTR. Several regions exhibited altered protection in extracts prepared from lymphoid cells as compared with HeLa cells, but there were minimal differences in the protection patterns between HTLV-infected and uninfected lymphoid extracts. A number of HTLV-I and HTLV-II LTR fragments which contained regions showing protection in DNase I footprinting were able to function as inducible enhancer elements in transient CAT gene expression assays in the presence of the HTLV-II tat protein. The alterations in the pattern of the cellular proteins which bind to the HTLV-I and HTLV-II LTRs may in part be responsible for differences in the transcriptional regulation of these two related viruses

A thermomechanical constitutive model for cemented granular materials with quantifiable internal variables. Part II - Validation and localization analysis

Science.gov (United States)

Das, Arghya; Tengattini, Alessandro; Nguyen, Giang D.; Viggiani, Gioacchino; Hall, Stephen A.; Einav, Itai

2014-10-01

We study the mechanical failure of cemented granular materials (e.g., sandstones) using a constitutive model based on breakage mechanics for grain crushing and damage mechanics for cement fracture. The theoretical aspects of this model are presented in Part I: Tengattini et al. (2014), A thermomechanical constitutive model for cemented granular materials with quantifiable internal variables, Part I - Theory (Journal of the Mechanics and Physics of Solids, 10.1016/j.jmps.2014.05.021). In this Part II we investigate the constitutive and structural responses of cemented granular materials through analyses of Boundary Value Problems (BVPs). The multiple failure mechanisms captured by the proposed model enable the behavior of cemented granular rocks to be well reproduced for a wide range of confining pressures. Furthermore, through comparison of the model predictions and experimental data, the micromechanical basis of the model provides improved understanding of failure mechanisms of cemented granular materials. In particular, we show that grain crushing is the predominant inelastic deformation mechanism under high pressures while cement failure is the relevant mechanism at low pressures. Over an intermediate pressure regime a mixed mode of failure mechanisms is observed. Furthermore, the micromechanical roots of the model allow the effects on localized deformation modes of various initial microstructures to be studied. The results obtained from both the constitutive responses and BVP solutions indicate that the proposed approach and model provide a promising basis for future theoretical studies on cemented granular materials.

Preliminary design analysis of the ALT-II limiter for TEXTOR

International Nuclear Information System (INIS)

Koski, J.A.; Boyd, R.D.; Kempka, S.M.; Romig, A.D. Jr.; Smith, M.F.; Watson, R.D.; Whitley, J.B.; Conn, R.W.; Grotz, S.P.

1983-01-01

Installation of a large toroidal belt pump limiter, Advanced Limiter Test II (ALT-II), on the TEXTOR tokamak at Juelich, FRG is anticipated for early 1986. This paper discusses the preliminary mechanical design and materials considerations undertaken as part of the feasibility study phase for ALT-II

Technical-economical feasibility of the wet oxidation process: Experiences on real scale plant. Part II; Fattibilita` tecnico-economica del processo di ossidazione ad umido: Esperienze di trattamento su impianto a piena scala. Parte II

Energy Technology Data Exchange (ETDEWEB)

Collivignarelli, Caro; Bertanza, Giorgio [Brescia, Univ. (Italy). Dipt. di Ingegneria Civile; Baldi, Marco [Pavia, Univ. (Italy). Dipt. di Ingegneria Idraulica e Ambientale; Bissolotti, Giorgio; Calvi Riccardo [SIAD Spa, Bergamo (Italy); Del Rio, Mauro; Pergetti, Mauro [AGAC, Reggio Emilia (Italy)

1997-04-01

In the first part of this work the wet oxidation process is compared with some other oxidation treatments (like Fenton oxidation, oxidation, also with UV light, incineration, ect.) in order to assess its proper application field. Besides, the main cases in which wet oxidation is employed in wastewater treatment are described and the results of some previous experiences of the authors are summarized. In the second part they discuss the results of an experimentation carried out on a real scale treatment plant (maximum inflow rate 1,5 m{sup 3}/h). The plant was fed with low biodegradable wastewaters (COD = 2.5 - 175 g/L) coming from different industrial sectors. The following process conditions were maintained: temperature = 280-300 deg C, final pressure = 11-12.5 MPa. From the results of the experimentation they concluded that this process is suitable or the pre-treatment of wastewaters with high non-biodegradable matter content, with COD initial concentrations from 10-20 up to 150 g/L. In these conditions, it is also convenient from the economical point of view, with respect to other chemical-physical of thermal processes. In order to achieve the full functionality within an industrial waste treatment facility, some operating measures are required aimed to homogenize the treated wastewater, which has carefully characterized.

The reform of Byzantine military and territorial organization under Justinian II

Directory of Open Access Journals (Sweden)

Cvetković Miloš

2016-01-01

Full Text Available This paper offers a contribution to the research of the initial stages in the evolution of the thematic system. It focuses on the role of Emperor Justinian II in the formation of the new imperial military and territorial organization. Byzantine scholars have determined a long time ago that it is Justinian II who should be credited with the founding of new military districts (themes in Hellas and Sicily. This paper, however, suggests that the formation of the themes in Thrace and Kibyrrhaiotai could also be considered a part of Justinian’s policy. In addition, the paper aims to highlight Justinian’s role in the formation of the frontier military and administrative system (the kleisourai of Strymon and Cappadocia, as well as in the reform of military and territorial organization in the Aegean basin. By creating new army units which were not based on the Late Roman heritage, Justinian essentially abandoned the principles that the Byzantine army had previously functioned on. Finally, the paper highlights the fact that the establishment of new thematic units under Emperor Justinian II was coupled with his extensive colonization measures. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 177032: Tradicija, inovacija i identitet u vizantijskom svetu

Cubby : Multiscreen Desktop VR Part III

NARCIS (Netherlands)

Djajadiningrat, J.P.; Gribnau, M.W.

2000-01-01

In this month's final episode of our 'Cubby: Multiscreen Desktop VR' trilogy we explain how you read the InputSprocket driver from part II, how you use it as input for the cameras from part I and how you calibrate the input device so that it leads to the correct head position.

GEOSAF Part II. Demonstration of the operational and long-term safety of geological disposal facilities for radioactive waste. IAEA international intercomparison and harmonization project

Energy Technology Data Exchange (ETDEWEB)

Kumano, Yumiko; Bruno, Gerard [International Atomic Energy Agency, Vienna (Austria). Vienna International Centre; Tichauer, Michael [IRSN, Institut de Radioprotection et de Surete Nucleaire, Fontenay-aux-Roses (France); Hedberg, Bengt [Swedish Radiation Safety Authority, Stockholm (Sweden)

2015-07-01

International intercomparison and harmonization projects are one of the mechanisms developed by the IAEA for examining the application and use of safety standards, with a view to ensuring their effectiveness and working towards harmonization of approaches to the safety of radioactive waste management. The IAEA has organized a number of international projects on the safety of radioactive waste management; in particular on the issues related to safety demonstration for radioactive waste management facilities. In 2008, GEOSAF, Demonstration of The Operational and Long-Term Safety of Geological Disposal Facilities for Radioactive Waste, project was initiated. This project was completed in 2011 by delivering a project report focusing on the safety case for geological disposal facilities, a concept that has gained in recent years considerable prominence in the waste management area and is addressed in several international safety standards. During the course of the project, it was recognized that little work was undertaken internationally to develop a common view on the safety approach related to the operational phase of a geological disposal although long-term safety of disposal facility has been discussed for several decades. Upon completion of the first part of the GEOSAF project, it was decided to commence a follow-up project aiming at harmonizing approaches on the safety of geological disposal facilities for radioactive waste through the development of an integrated safety case covering both operational and long-term safety. The new project was named as GEOSAF Part II, which was initiated in 2012 initially as 2-year project, involving regulators and operators. GEOSAF Part II provides a forum to exchange ideas and experience on the development and review of an integrated operational and post-closure safety case for geological disposal facilities. It also aims at providing a platform for knowledge transfer. The project is of particular interest to regulatory

Cardiac nuclear medicine, part II: diagnosis of coronary artery diseas

International Nuclear Information System (INIS)

Polak, J.F.; Holman, B.L.

1981-01-01

Diagnosing coronary artery disease is difficult and requires careful consideration of the roles and limitations of the tests used. Standard ECG tests are not reliable indicators of the presence of disease in asymptomatic patients. Thallium stress testing to assess ischemia and exercise ventriculography to assess functional status of the heart are limited in sensitivity and specificity. This is the second of a three-part series on cardiac nuclear medicine. Part I (Med. Instrum., May-June, 1981) focused on the commonly used examinations in cardiac physiology and pathophysiology. Part III will focus on myocardial infarction and other cardiac diseases

Unraveling uranium induced oxidative stress related responses in Arabidopsis thaliana seedlings. Part II: responses in the leaves and general conclusions

Energy Technology Data Exchange (ETDEWEB)

Vanhoudt, Nathalie, E-mail: nvanhoud@sckcen.be [Belgian Nuclear Research Center (SCK-CEN), Biosphere Impact Studies, Boeretang 200, 2400 Mol (Belgium); Hasselt University, Environmental Biology, Centre for Environmental Sciences, Agoralaan Building D, 3590 Diepenbeek (Belgium); Cuypers, Ann [Hasselt University, Environmental Biology, Centre for Environmental Sciences, Agoralaan Building D, 3590 Diepenbeek (Belgium); Horemans, Nele [Belgian Nuclear Research Center (SCK-CEN), Biosphere Impact Studies, Boeretang 200, 2400 Mol (Belgium); Remans, Tony; Opdenakker, Kelly; Smeets, Karen [Hasselt University, Environmental Biology, Centre for Environmental Sciences, Agoralaan Building D, 3590 Diepenbeek (Belgium); Bello, Daniel Martinez [Hasselt University, Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Agoralaan Building D, 3590 Diepenbeek (Belgium); Havaux, Michel [Commissariat a l' Energie Atomique (CEA)/Cadarache, Direction des Sciences du Vivant, Departement d' Ecophysiologie Vegetale et de Microbiologie, Laboratoire d' Ecophysiologie de la Photosynthese, 13108 Saint-Paul-lez-Durance (France); Wannijn, Jean; Van Hees, May [Belgian Nuclear Research Center (SCK-CEN), Biosphere Impact Studies, Boeretang 200, 2400 Mol (Belgium); Vangronsveld, Jaco [Hasselt University, Environmental Biology, Centre for Environmental Sciences, Agoralaan Building D, 3590 Diepenbeek (Belgium); Vandenhove, Hildegarde [Belgian Nuclear Research Center (SCK-CEN), Biosphere Impact Studies, Boeretang 200, 2400 Mol (Belgium)

2011-06-15

The cellular redox balance seems an important modulator under heavy metal stress. While for other heavy metals these processes are well studied, oxidative stress related responses are also known to be triggered under uranium stress but information remains limited. This study aimed to further unravel the mechanisms by which plants respond to uranium stress. Seventeen-day-old Arabidopsis thaliana seedlings, grown on a modified Hoagland solution under controlled conditions, were exposed to 0, 0.1, 1, 10 and 100 {mu}M uranium for 1, 3 and 7 days. While in Part I of this study oxidative stress related responses in the roots were discussed, this second Part II discusses oxidative stress related responses in the leaves and general conclusions drawn from the results of the roots and the leaves will be presented. As several responses were already visible following 1 day exposure, when uranium concentrations in the leaves were negligible, a root-to-shoot signaling system was suggested in which plastids could be important sensing sites. While lipid peroxidation, based on the amount of thiobarbituric acid reactive compounds, was observed after exposure to 100 {mu}M uranium, affecting membrane structure and function, a transient concentration dependent response pattern was visible for lipoxygenase initiated lipid peroxidation. This transient character of uranium stress responses in leaves was emphasized by results of lipoxygenase (LOX2) and antioxidative enzyme transcript levels, enzyme capacities and glutathione concentrations both in time as with concentration. The ascorbate redox balance seemed an important modulator of uranium stress responses in the leaves as in addition to the previous transient responses, the total ascorbate concentration and ascorbate/dehydroascorbate redox balance increased in a concentration and time dependent manner. This could represent either a slow transient response or a stable increase with regard to plant acclimation to uranium stress

Controlled Nonlinear Stochastic Delay Equations: Part I: Modeling and Approximations

International Nuclear Information System (INIS)

Kushner, Harold J.

2012-01-01

This two-part paper deals with “foundational” issues that have not been previously considered in the modeling and numerical optimization of nonlinear stochastic delay systems. There are new classes of models, such as those with nonlinear functions of several controls (such as products), each with is own delay, controlled random Poisson measure driving terms, admissions control with delayed retrials, and others. There are two basic and interconnected themes for these models. The first, dealt with in this part, concerns the definition of admissible control. The classical definition of an admissible control as a nonanticipative relaxed control is inadequate for these models and needs to be extended. This is needed for the convergence proofs of numerical approximations for optimal controls as well as to have a well-defined model. It is shown that the new classes of admissible controls do not enlarge the range of the value functions, is closed (together with the associated paths) under weak convergence, and is approximatable by ordinary controls. The second theme, dealt with in Part II, concerns transportation equation representations, and their role in the development of numerical algorithms with much reduced memory and computational requirements.

Vaccines for viral and bacterial pathogens causing acute gastroenteritis: Part II: Vaccines for Shigella, Salmonella, enterotoxigenic E. coli (ETEC) enterohemorragic E. coli (EHEC) and Campylobacter jejuni

Science.gov (United States)

O’Ryan, Miguel; Vidal, Roberto; del Canto, Felipe; Carlos Salazar, Juan; Montero, David

2015-01-01

In Part II we discuss the following bacterial pathogens: Shigella, Salmonella (non-typhoidal), diarrheogenic E. coli (enterotoxigenic and enterohemorragic) and Campylobacter jejuni. In contrast to the enteric viruses and Vibrio cholerae discussed in Part I of this series, for the bacterial pathogens described here there is only one licensed vaccine, developed primarily for Vibrio cholerae and which provides moderate protection against enterotoxigenic E. coli (ETEC) (Dukoral®), as well as a few additional candidates in advanced stages of development for ETEC and one candidate for Shigella spp. Numerous vaccine candidates in earlier stages of development are discussed. PMID:25715096

Synchrotron X-ray CT characterization of titanium parts fabricated by additive manufacturing. Part II. Defects.

Science.gov (United States)

Scarlett, Nicola Vivienne Yorke; Tyson, Peter; Fraser, Darren; Mayo, Sheridan; Maksimenko, Anton

2016-07-01

Synchrotron X-ray tomography (SXRT) has been applied to the study of defects within three-dimensional printed titanium parts. These parts were made using the Arcam EBM(®) (electron beam melting) process which uses powdered titanium alloy, Ti64 (Ti alloy with approximately 6%Al and 4%V) as the feed and an electron beam for the sintering/welding. The experiment was conducted on the Imaging and Medical Beamline of the Australian Synchrotron. The samples represent a selection of complex shapes with a variety of internal morphologies. Inspection via SXRT has revealed a number of defects which may not otherwise have been seen. The location and nature of such defects combined with detailed knowledge of the process conditions can contribute to understanding the interplay between design and manufacturing strategy. This fundamental understanding may subsequently be incorporated into process modelling, prediction of properties and the development of robust methodologies for the production of defect-free parts.

Charged NUT field : [Part] I. Motion of test particles and [Part] II. Cosmic censorship

International Nuclear Information System (INIS)

Krori, K.D.

1981-01-01

Some properties of the charged NUT field are studied. In the first part of the paper, some general aspects of the charged NUT field have been investigated using uncharged and charged particles. The behaviour of the particles near the singularity has also been considered. In the second part of the paper, the charged NUT sources in the context of cosmic censorship hypothesis are studied. Motion of charged particles in the equatorial plane and along the axis is considered. From this investigation the interesting result is discovered that by such a bombardment of charged test particles, the existing event horizons cannot be destroyed but, in contrast to the Reissner-Nordstrom field, naked singularities do not get enveloped by event horizons. (author)

The Role of Formal and Informal Forces in Shaping Consumption and Implications for Sustainable Society: Part II

Directory of Open Access Journals (Sweden)

Oksana Mont

2010-08-01

Full Text Available Looking at consumption from a societal perspective, we can see that purchasing and behavior decisions are influenced by many factors, not the least which are what the people around us and in the media are doing. Other factors include economic influences, the marketing of products and technological innovations, and regulations governing consumption. This article, Part II, argues that in order to understand consumption, we need to move beyond the dominant (economic understanding of consumers and consumer behavior, and think about the origins of our preferences, needs, and desires. A thorough understanding of consumption is informed by the contributions of sociologists, psychologists, anthropologists, and behavioral scientists, who study the socio-cultural, social, and psychological contexts in which consumer behavior is embedded. These disciplines offer rich and complex explanations of human behavior, which in turn illuminate the discussion on how consumer behavior can be made more sustainable.

Compressor Part II: Volute Flow Predictions

Directory of Open Access Journals (Sweden)

Yu-Tai Lee

1999-01-01

Full Text Available A numerical method that solves the Reynolds-averaged Navier-Stokes equations is used to study an inefficient component of a shipboard air-conditioning HCFC-124 compressor system. This high-loss component of the centrifugal compressor was identified as the volute through a series of measurements given in Part I of the paper. The predictions were made using three grid topologies. The first grid closes the connection between the cutwater and the discharge diffuser. The other two grids connect the cutwater area with the discharge diffuser. Experiments were performed to simulate both the cutwater conditions used in the predictions. Surface pressures along the outer wall and near the inlet of the volute were surveyed for comparisons with the predictions. Good agreements between the predicted results and the measurements validate the calculations. Total pressure distributions and flow stream traces from the prediction results support the loss distribution through the volute. A modified volute configuration is examined numerically for further loss comparison.

PGE Production in Southern Africa, Part II: Environmental Aspects

Directory of Open Access Journals (Sweden)

Benedikt Buchspies

2017-11-01

Full Text Available Platinum group elements (PGEs, 6E PGE = Pt + Pd + Rh + Ru + Ir + Au are used in numerous applications that seek to reduce environmental impacts of mobility and energy generation. Consequently, the future demand for PGEs is predicted to increase. Previous studies indicate that environmental impacts of PGE production change over time emphasizing the need of up-to-date data and assessments. In this context, an analysis of environmental aspects of PGE production is needed to support the environmental assessment of technologies using PGEs, to reveal environmental hotspots within the production chain and to identify optimization potential. Therefore, this paper assesses greenhouse gas (GHG emissions, cumulative fossil energy demand (CEDfossil, sulfur dioxide (SO2 emissions and water use of primary PGE production in Southern Africa, where most of today’s supply originates from. The analysis shows that in 2015, emissions amounted to 45 t CO2-eq. and 502 kg SO2 per kg 6E PGE in the case GHG and SO2 emissions, respectively. GHG emissions are dominated by emissions from electricity provision contributing more than 90% to the overall GHG emissions. The CEDfossil amounted to 0.60 TJ per kg 6E PGE. A detailed analysis of the CEDfossil reveals that electricity provision based on coal power consumes the most fossil energy carriers among all energy forms. Results show that the emissions are directly related to the electricity demand. Thus, the reduction in the electricity demand presents the major lever to reduce the consumption of fossil energy resources and the emission of GHGs and SO2. In 2015, the water withdrawal amounted to 0.272 million L per kg 6E PGE. Additionally, 0.402 million L of recycled water were used per kg 6E PGE. All assessed indicators except ore grades and production volumes reveal increasing trends in the period from 2010 to 2015. It can be concluded that difficult market conditions (see part I of this paper series and increasing

Introduction of organic/hydro-organic matrices in inductively coupled plasma optical emission spectrometry and mass spectrometry: A tutorial review. Part II. Practical considerations

Energy Technology Data Exchange (ETDEWEB)

Leclercq, Amélie, E-mail: amelie.leclercq@cea.fr [CEA Saclay, DEN, DANS, DPC, SEARS, Laboratoire de développement Analytique Nucléaire Isotopique et Elémentaire, 91191 Gif-sur-Yvette (France); Nonell, Anthony, E-mail: anthony.nonell@cea.fr [CEA Saclay, DEN, DANS, DPC, SEARS, Laboratoire de développement Analytique Nucléaire Isotopique et Elémentaire, 91191 Gif-sur-Yvette (France); Todolí Torró, José Luis, E-mail: jose.todoli@ua.es [Universidad de Alicante, Departamento de Quimica Analitica, Nutricion y Bromatología, Ap. de Correos, 99, 03080 Alicante (Spain); Bresson, Carole, E-mail: carole.bresson@cea.fr [CEA Saclay, DEN, DANS, DPC, SEARS, Laboratoire de développement Analytique Nucléaire Isotopique et Elémentaire, 91191 Gif-sur-Yvette (France); Vio, Laurent, E-mail: laurent.vio@cea.fr [CEA Saclay, DEN, DANS, DPC, SEARS, Laboratoire de développement Analytique Nucléaire Isotopique et Elémentaire, 91191 Gif-sur-Yvette (France); Vercouter, Thomas, E-mail: thomas.vercouter@cea.fr [CEA Saclay, DEN, DANS, DPC, SEARS, Laboratoire de développement Analytique Nucléaire Isotopique et Elémentaire, 91191 Gif-sur-Yvette (France); Chartier, Frédéric, E-mail: frederic.chartier@cea.fr [CEA Saclay, DEN, DANS, DPC, 91191 Gif-sur-Yvette (France)

2015-07-23

Graphical abstract: This tutorial review is dedicated to the analysis of organic/hydro-organic matrices by ICP techniques. A state-of-the-art focusing on sample introduction, relevant operating parameters optimization and analytical strategies for elemental quantification is provided. - Highlights: • Practical considerations to perform analyses in organic/hydro-organic matrices. • Description, benefits and drawbacks of recent introduction devices. • Optimization to improve plasma tolerance towards organic/hydro-organic matrices. • Analytical strategies for elemental quantification in organic/hydro-organic matrices. - Abstract: Inductively coupled plasma optical emission spectrometry (ICP-OES) and mass spectrometry (ICP-MS) are increasingly used to carry out analyses in organic/hydro-organic matrices. The introduction of such matrices into ICP sources is particularly challenging and can be the cause of numerous drawbacks. This tutorial review, divided in two parts, explores the rich literature related to the introduction of organic/hydro-organic matrices in ICP sources. Part I provided theoretical considerations associated with the physico-chemical properties of such matrices, in an attempt to understand the induced phenomena. Part II of this tutorial review is dedicated to more practical considerations on instrumentation, instrumental and operating parameters, as well as analytical strategies for elemental quantification in such matrices. Two important issues are addressed in this part: the first concerns the instrumentation and optimization of instrumental and operating parameters, pointing out (i) the description, benefits and drawbacks of different kinds of nebulization and desolvation devices and the impact of more specific instrumental parameters such as the injector characteristics and the material used for the cone; and, (ii) the optimization of operating parameters, for both ICP-OES and ICP-MS. Even if it is at the margin of this tutorial review

Introduction of organic/hydro-organic matrices in inductively coupled plasma optical emission spectrometry and mass spectrometry: A tutorial review. Part II. Practical considerations

International Nuclear Information System (INIS)

Leclercq, Amélie; Nonell, Anthony; Todolí Torró, José Luis; Bresson, Carole; Vio, Laurent; Vercouter, Thomas; Chartier, Frédéric

2015-01-01

Graphical abstract: This tutorial review is dedicated to the analysis of organic/hydro-organic matrices by ICP techniques. A state-of-the-art focusing on sample introduction, relevant operating parameters optimization and analytical strategies for elemental quantification is provided. - Highlights: • Practical considerations to perform analyses in organic/hydro-organic matrices. • Description, benefits and drawbacks of recent introduction devices. • Optimization to improve plasma tolerance towards organic/hydro-organic matrices. • Analytical strategies for elemental quantification in organic/hydro-organic matrices. - Abstract: Inductively coupled plasma optical emission spectrometry (ICP-OES) and mass spectrometry (ICP-MS) are increasingly used to carry out analyses in organic/hydro-organic matrices. The introduction of such matrices into ICP sources is particularly challenging and can be the cause of numerous drawbacks. This tutorial review, divided in two parts, explores the rich literature related to the introduction of organic/hydro-organic matrices in ICP sources. Part I provided theoretical considerations associated with the physico-chemical properties of such matrices, in an attempt to understand the induced phenomena. Part II of this tutorial review is dedicated to more practical considerations on instrumentation, instrumental and operating parameters, as well as analytical strategies for elemental quantification in such matrices. Two important issues are addressed in this part: the first concerns the instrumentation and optimization of instrumental and operating parameters, pointing out (i) the description, benefits and drawbacks of different kinds of nebulization and desolvation devices and the impact of more specific instrumental parameters such as the injector characteristics and the material used for the cone; and, (ii) the optimization of operating parameters, for both ICP-OES and ICP-MS. Even if it is at the margin of this tutorial review

A revision of the genus Muricea Lamouroux, 1821 (Anthozoa, Octocorallia) in the eastern Pacific. Part II.

Science.gov (United States)

Breedy, Odalisca; Guzman, Hector M

2016-01-01

The species of the genus Muricea were mainly described from 1846 to 1870. After that very few contributions were published. Although the highest richness of Muricea species is in the eastern Pacific shallow waters, a comprehensive systematic study of the genus does not exist. Recently we started a taxonomic review of the genus in order to validate the status of four species previously included in the genus Eumuricea. Herein we present the second part of the Muricea revision dealing with the species-group characterised by shelf-like calyces instead of tubular-like calyces (the Muricea squarrosa-group). Original type material was morphologically analysed and illustrated using optical and scanning electron microscopy. Comparative character tables are provided for the genus. The taxonomic status of the species was analysed and established by designating lectotypes, alternatively by recognising a holotype by monotypy. We conclude that the genus Muricea comprises 20 valid species, including the previous four in the Muricea squarrosa-group. We propose 10 lectotypes, a new combination and three more species groups for the genus based on morphology: the Muricea fruticosa-group, Muricea plantaginea-group and Muricea austera-group.

LHC related projects and studies - Part (II)

International Nuclear Information System (INIS)

Rossi, L.; De Maria, R.

2012-01-01

The session was devoted to address some aspects of the HL-LHC (High Luminosity LHC) project and explore ideas on new machines for the long term future. The session had two parts. The former focused on some of the key issues of the HL-LHC projects: beam current limits, evolution of the collimation system, research plans for the interaction region magnets and crab cavities. The latter explored the ideas for the long term future projects (LHeC and HE-LHC) and how the current research-development program for magnets and RF structures could fit in the envisaged scenarios

[Neurohumoral mechanisms for vasovagal syncopes. Part II].

Science.gov (United States)

Gajek, Jacek; Zyśko, Dorota

2003-04-01

Vasovagal syncope is defined as a reflex loss of consciousness related to reaction to various stimuli as orthostatic stress, pain or emotions connected with loss of muscle postural tone. In the second part of the paper the authors describe the possible role of the particular neurohumoral factors and autonomic nervous system in the development of vasovagal syncope. The studies on the involvement of neurohumoral factors in vasovagal syncope can play a key role in a more precise evaluation of affected patients, long term prophylaxis against syncopal events and may contribute to development of more reliable diagnostic tests.

DNA methyltransferase inhibitor CDA-II inhibits myogenic differentiation

International Nuclear Information System (INIS)

Chen, Zirong; Jin, Guorong; Lin, Shuibin; Lin, Xiumei; Gu, Yumei; Zhu, Yujuan; Hu, Chengbin; Zhang, Qingjiong; Wu, Lizi; Shen, Huangxuan

2012-01-01

Highlights: ► CDA-II inhibits myogenic differentiation in a dose-dependent manner. ► CDA-II repressed expression of muscle transcription factors and structural proteins. ► CDA-II inhibited proliferation and migration of C2C12 myoblasts. -- Abstract: CDA-II (cell differentiation agent II), isolated from healthy human urine, is a DNA methyltransferase inhibitor. Previous studies indicated that CDA-II played important roles in the regulation of cell growth and certain differentiation processes. However, it has not been determined whether CDA-II affects skeletal myogenesis. In this study, we investigated effects of CDA-II treatment on skeletal muscle progenitor cell differentiation, migration and proliferation. We found that CDA-II blocked differentiation of murine myoblasts C2C12 in a dose-dependent manner. CDA-II repressed expression of muscle transcription factors, such as Myogenin and Mef2c, and structural proteins, such as myosin heavy chain (Myh3), light chain (Mylpf) and MCK. Moreover, CDA-II inhibited C1C12 cell migration and proliferation. Thus, our data provide the first evidence that CDA-II inhibits growth and differentiation of muscle progenitor cells, suggesting that the use of CDA-II might affect skeletal muscle functions.

The Influence of Injection Pockets on the Performance of Tilting-Pad Thrust Bearings: Part II – Comparison Between Theory and Experiment

DEFF Research Database (Denmark)

Heinrichson, Niels; Santos, Ilmar

2006-01-01

This is Part II of a two-part series of papers describing the effects of high pressure injection pockets on the operating conditions of tilting-pad thrust bearings. Measurements of the distribution of pressure and oil film thickness are presented for tilting-pad thrust bearing pads of approximately...... 100 cm2 surface area. Two pads are measured in a laboratory test-rig at loads of approximately 0.5, 1.5 and 4.0 MPa and velocities of up to 33 m/s. One pad has a plain surface. The other pad has a conical injection pocket at the pivot point and a leading edge taper. The measurements are compared...... to theoretical values obtained using a three dimensional thermo-elasto-hydrodynamic (TEHD) numerical model. At low and intermediate loads the theoretical pressure distribution corresponds well to the measured values for both pads although the influence of the pocket is slightly underestimated. At high loads...

Histologic features of alopecias: part II: scarring alopecias.

Science.gov (United States)

Bernárdez, C; Molina-Ruiz, A M; Requena, L

2015-05-01

The diagnosis of disorders of the hair and scalp can generally be made on clinical grounds, but clinical signs are not always diagnostic and in some cases more invasive techniques, such as a biopsy, may be necessary. This 2-part article is a detailed review of the histologic features of the main types of alopecia based on the traditional classification of these disorders into 2 major groups: scarring and nonscarring alopecias. Scarring alopecias are disorders in which the hair follicle is replaced by fibrous scar tissue, a process that leads to permanent hair loss. In nonscarring alopecias, the follicles are preserved and hair growth can resume when the cause of the problem is eliminated. In the second part of this review, we describe the histologic features of the main forms of scarring alopecia. Since a close clinical-pathological correlation is essential for making a correct histopathologic diagnosis of alopecia, we also include a brief description of the clinical features of the principal forms of this disorder. Copyright © 2014 Elsevier España, S.L.U. and AEDV. All rights reserved.

Rise, fall and resurrection of chromosome territories: a historical perspective. Part II. Fall and resurrection of chromosome territories during the 1950s to 1980s. Part III. Chromosome territories and the functional nuclear architecture: experiments and models from the 1990s to the present.

Science.gov (United States)

Cremer, T; Cremer, C

2006-01-01

Part II of this historical review on the progress of nuclear architecture studies points out why the original hypothesis of chromosome territories from Carl Rabl and Theodor Boveri (described in part I) was abandoned during the 1950s and finally proven by compelling evidence forwarded by laser-uv-microbeam studies and in situ hybridization experiments. Part II also includes a section on the development of advanced light microscopic techniques breaking the classical Abbe limit written for readers with little knowledge about the present state of the theory of light microscopic resolution. These developments have made it possible to perform 3D distance measurements between genes or other specifically stained, nuclear structures with high precision at the nanometer scale. Moreover, it has become possible to record full images from fluorescent structures and perform quantitative measurements of their shapes and volumes at a level of resolution that until recently could only be achieved by electron microscopy. In part III we review the development of experiments and models of nuclear architecture since the 1990s. Emphasis is laid on the still strongly conflicting views about the basic principles of higher order chromatin organization. A concluding section explains what needs to be done to resolve these conflicts and to come closer to the final goal of all studies of the nuclear architecture, namely to understand the implications of nuclear architecture for nuclear functions.

Aesthetic Pursuits: Windows, Frames, Words, Images--Part II

Science.gov (United States)

Burke, Ken

2005-01-01

In Part I of this study (Burke, 2005), the author presented the essentials of Image Presentation Theory--IPT--and its application to the analytical explication of various spatial designs in and psychological responses to images, from the illusions of depth in what is referred to as "windows" in cinema theory to the more patterned abstractions of…

The Search for Another Earth – Part II

Indian Academy of Sciences (India)

In this part, we will describe various kinds of ... the Earth will also be discussed. 1. .... life. system is oxygen rich because the interstellar cloud from which the Sun and the solar planets were born .... a habitable planet must be rocky in order to sustain liquid ... helped in keeping the atmosphere of the Earth habitable for a long.

Oral Assessment Kit, Levels II & III. Draft.

Science.gov (United States)

Agrelo-Gonzalez, Maria; And Others

The assessment packet includes a series of oral tests to help develop speaking as an integral part of second language instruction at levels II and III. It contains: 8 mini-tests for use at level II; 9 mini-tests for use at level III; a rating scale and score sheet masters for evaluating performance on these tests; and a collection of suggested…

[Low grade renal trauma (Part II): diagnostic validity of ultrasonography].

Science.gov (United States)

Grill, R; Báca, V; Otcenásek, M; Zátura, F

2010-04-01

The aim of the study was to verify whether ultrasonography can be considered a reliable method for the diagnosis of low-grade renal trauma. The group investigated included patients with grade I or grade II blunt renal trauma, as classified by the AAST grading system, in whom ultrasonography alone or in conjunction with computed tomography was used as a primary diagnostic method. B-mode ultrasound with a transabdominal probe working at frequencies of 2.5 to 5.0 MHz was used. Every finding of post-traumatic changes in the renal tissues, i.e., post-contusion hypotonic infiltration of the renal parenchyma or subcapsular haematoma, was included. The results were statistically evaluated by the Chi-square test with the level of significance set at 5%, using Epi Info Version 6 CZ software. The group comprised 112 patients (43 women, 69 men) aged between 17 and 82 years (average, 38 years). It was possible to diagnose grade I or grade II renal injury by ultrasonography in only 60 (54%) of them. The statistical significance of ultrasonography as the only imaging method for the diagnosis of low-grade renal injury was not confirmed (p=0.543) Low-grade renal trauma is a problem from the diagnostic point of view. It usually does not require revision surgery and, if found during repeat surgery for more serious injury of another organ, it usually does not receive attention. Therefore, the macroscopic presentation of grade I and grade II renal injury is poorly understood, nor are their microscopic findings known, because during revision surgery these the traumatised kidneys are not usually removed and their injuries at autopsy on the patients who died of multiple trauma are not recorded either. The results of this study demonstrated that the validity of ultrasonography for the diagnosis of low-grade renal injury is not significant, because this examination can reveal only some of the renal injuries such as perirenal haematoma. An injury to the renal parenchyma is also indicated by

Introduction to Part III: Application of LCA in Practice

DEFF Research Database (Denmark)

Rosenbaum, Ralph K.

2018-01-01

While Part II of this book presents the theoretical foundation and methodology of LCA, Part III is dedicated to a comprehensive discussion of how this methodology has been adapted and applied in practice. The chapters of Part III provide an easily readable and accessible introduction to different...

Multi-instantons and exact results II: specific cases, higher-order effects, and numerical calculations

International Nuclear Information System (INIS)

Zinn-Justin, Jean; Jentschura, Ulrich D.

2004-01-01

In this second part of the treatment of instantons in quantum mechanics, the focus is on specific calculations related to a number of quantum mechanical potentials with degenerate minima. We calculate the leading multi-instanton contributions to the partition function, using the formalism introduced in the first part of the treatise [Ann. Phys. (N. Y.) (previous issue) (2004)]. The following potentials are considered: (i) asymmetric potentials with degenerate minima, (ii) the periodic cosine potential, (iii) anharmonic oscillators with radial symmetry, and (iv) a specific potential which bears an analogy with the Fokker-Planck equation. The latter potential has the peculiar property that the perturbation series for the ground-state energy vanishes to all orders and is thus formally convergent (the ground-state energy, however, is non-zero and positive). For the potentials (ii), (iii), and (iv), we calculate the perturbative B-function as well as the instanton A-function to fourth order in g. We also consider the double-well potential in detail, and present some higher-order analytic as well as numerical calculations to verify explicitly the related conjectures up to the order of three instantons. Strategies analogous to those outlined here could result in new conjectures for problems where our present understanding is more limited

Effect of Previous Irradiation on Vascular Thrombosis of Microsurgical Anastomosis: A Preclinical Study in Rats

Science.gov (United States)

Gallardo-Calero, Irene; López-Fernández, Alba; Romagosa, Cleofe; Vergés, Ramona; Aguirre-Canyadell, Marius; Soldado, Francisco; Velez, Roberto

2016-01-01

Background: The objective of the present investigation was to compare the effect of neoadjuvant irradiation on the microvascular anastomosis in cervical bundle using an experimental model in rats. Methods: One hundred forty male Sprague–Dawley rats were allocated into 4 groups: group I, control, arterial microanastomosis; group II, control, venous microanastomosis; group III, arterial microanastomosis with previous irradiation (20 Gy); and group IV, venous microanastomosis with previous irradiation (20 Gy). Clinical parameters, technical values of anastomosis, patency, and histopathological parameters were evaluated. Results: Irradiated groups (III and IV) and vein anastomosis groups (II and IV) showed significantly increased technical difficulties. Group IV showed significantly reduced patency rates (7/35) when compared with the control group (0/35). Radiotherapy significantly decreased the patency rates of the vein (7/35) when compared with the artery (1/35). Groups III and IV showed significantly reduced number of endothelial cells and also showed the presence of intimal thickening and adventitial fibrosis as compared with the control group. Conclusion: Neoadjuvant radiotherapy reduces the viability of the venous anastomosis in a preclinical rat model with a significant increase in the incidence of vein thrombosis. PMID:27975009

Guidelines for acute ischemic stroke treatment: part II: stroke treatment

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Sheila Cristina Ouriques Martins

2012-11-01

Full Text Available The second part of these Guidelines covers the topics of antiplatelet, anticoagulant, and statin therapy in acute ischemic stroke, reperfusion therapy, and classification of Stroke Centers. Information on the classes and levels of evidence used in this guideline is provided in Part I. A translated version of the Guidelines is available from the Brazilian Stroke Society website (www.sbdcv.com.br.

Indigenous instrumentation for mass spectrometry: Part II - development of plasma source mass spectrometers. PD-5-3

International Nuclear Information System (INIS)

Nataraju, V.

2007-01-01

The growing demands from analytical community, for a precise isotope ratio and ultra trace concentration measurements, has lead to significant improvement in mass spectrometer instrumentation development with respect to sensitivity, detection limits, precision and accuracy. Among the many analytical techniques available, plasma source mass spectrometers like Inductively Coupled Plasma Mass Spectrometry (ICPMS), multi collector (MC) ICPMS and Glow Discharge Mass Spectrometry (GDMS), have matured into reliable tools for the above applications. Where as ICPMS is by far the most successful method for aqueous solutions, GDMS is being applied for bulk and impurity analysis of conducting as well non-conducting solids. VPID, BARC has been developing mass spectrometers for different inorganic applications of DAE users. Over the years expertise has been developed in all the aspects of mass spectrometry instrumentation. Part 1 of this indigenous instrumentation on mass spectrometry gives details of magnetic sector instruments with either EI or TI source for isotopic ratio analysis. The present paper is a continuation of that on plasma source and quadrupole mass spectrometers. This paper covers i) ICP-QMS, ii) MC-ICPMS, iii) GDMS and iv) QMS

UNISIST II: Special Report.

Science.gov (United States)

Hattery, Lowell H., Ed.

1979-01-01

The major part of this report of the Intergovernmental Conference on Scientific and Technical Information (UNISIST II), held in Paris May 28-June 1, 1979, focuses on three sets of recommendations which were unanimously approved after combining the recommendations proposed by various groups and blocs: (1) recommendations to the United Nations…

Synthesis and characterisation of Cu(II), Ni(II), Mn(II), Zn(II) and VO(II ...

Indian Academy of Sciences (India)

Unknown

Synthesis and characterisation of Cu(II), Ni(II), Mn(II), Zn(II) and VO(II) Schiff base complexes derived from o-phenylenediamine and acetoacetanilide. N RAMAN*, Y PITCHAIKANI RAJA and A KULANDAISAMY. Department of Chemistry, VHNSN College, Virudhunagar 626 001, India e-mail: ra_man@123india.com.

Americium/Curium Vitrification Pilot Tests - Part II

International Nuclear Information System (INIS)

Marra, J.E.; Baich, M.A.; Fellinger, A.P.; Hardy, B.J.; Herman, D.T.; Jones, T.M.; Miller, C.B.; Miller, D.H.; Snyder, T. K.; Stone, M.E.

1998-05-01

Isotopes of americium (Am) and curium (Cm) were produced in the past at the Savannah River Site (SRS) for research, medical, and radiological applications. These highly radioactive and valuable isotopes have been stored in an SRS reprocessing facility for a number of years. Vitrification of this solution will allow the material to be more safely stored until it is transported to the DOE Oak Ridge Reservation for use in research and medical applications. A previous paper described operation results from the Am-Cm Melter 2A pilot system, a full-scale non-radioactive pilot facility. This paper presents the results from continued testing in the Pilot Facility and also describes efforts taken to look at alternative vitrification process operations and flowsheets designed to address the problems observed during melter 2A pilot testing

Synopsis Of The subfamily Spiranthoideae (Orchidaceae) In Colombia, Part II

International Nuclear Information System (INIS)

Duenas Gomez, Hilda del Carmen; Fernandez Alonso, Jose Luis

2009-01-01

As second and last contribution to the synoptic treatment of the Spiranthoideae for Colombia, the synopsis of the tribes Spirantheae (subtribes Cyclopogoninae: 3 genera, 41 species and Stenorrhynchidinae: 9 genera, 15 species) and Cranichideae (5 genera, 53 species), is presented. The most diverse genera in these tribes are: Cranichis (20 species), Cyclopogon (17), Ponthieva (15) and Pelexia (14). As part of the results of this study: a)- The transfer of Cybebus from the subtribe Spiranthinae (where it was commonly placed) to the subtribe Stenorhinchidinae, is proposed, based on the floral morphology (the rostellum and viscidium structure). b)- two genera are reported for Colombia as new records, each one with one species: Lyroglossa (L. grisebachii) and Helonoma; for the latter the new combination Helonoma peruviana (Szlach.) Salazar, Duenas and Fern. Alonso is proposed. c) New records in the previously known list of Colombian orchids are presented: Coccineorchis (C. cristata, C. navarrensis), Cyclopogon (C. maldonadoanus, C. olivaceus, C. rimbachii), Pelexia (P. hirta, P. palmorchidis), Ponthieva (P. venusta), and Sarcoglottis (S. grandiflora, S. maasorum, S. neglecta, S. stergiosii). d)- And additional 19 new records of species belonging to Aspidogyne and Microchilus, not reported in Duenas and Fernandez-Alonso (2007), are also included. e)- Finally an analysis of the distribution and diversity of the genera of this subfamily, according to altitude ranges in Colombia is presented. This group has predominant Andean distribution, being found mainly between 1300 and 3600 m of altitude. Genera broadly distributed as Microchilus, Gomphichis, Cyclopogon, Pelexia, Sarcoglottis, Coccineorchis, Stenorrhynchos, Cranichis and Ponthieva, are found almost from the level up to 3000 m, in all the regions of the country. In contrast, Beloglottis, Brachystele, Cybebus, Eltroplectris, Hapalorchis, Helonoma, Lankesterella, Lyroglossa, Kreodanthus, Pteroglossa and Sauroglossum

Biologically active new Fe(II, Co(II, Ni(II, Cu(II, Zn(II and Cd(II complexes of N-(2-thienylmethylenemethanamine

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C. SPÎNU

2008-04-01

Full Text Available Iron(II, cobalt(II, nickel (II, copper (II, zinc(II and cadmium(II complexes of the type ML2Cl2, where M is a metal and L is the Schiff base N-(2-thienylmethylenemethanamine (TNAM formed by the condensation of 2-thiophenecarboxaldehyde and methylamine, were prepared and characterized by elemental analysis as well as magnetic and spectroscopic measurements. The elemental analyses suggest the stoichiometry to be 1:2 (metal:ligand. Magnetic susceptibility data coupled with electronic, ESR and Mössbauer spectra suggest a distorted octahedral structure for the Fe(II, Co(II and Ni(II complexes, a square-planar geometry for the Cu(II compound and a tetrahedral geometry for the Zn(II and Cd(II complexes. The infrared and NMR spectra of the complexes agree with co-ordination to the central metal atom through nitrogen and sulphur atoms. Conductance measurements suggest the non-electrolytic nature of the complexes, except for the Cu(II, Zn(II and Cd(II complexes, which are 1:2 electrolytes. The Schiff base and its metal chelates were screened for their biological activity against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa and the metal chelates were found to possess better antibacterial activity than that of the uncomplexed Schiff base.

História de uma experiência singular de ensino – Parte II: o caso das disciplinas “Físicas Básicas”, da UFBA

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José Fernando Moura Rocha

2016-09-01

Full Text Available http://dx.doi.org/10.5007/2175-7941.2016v33n2p527   Neste trabalho relata-se uma experiência singular de ensino, realizada no Curso de Física, Licenciatura, noturno, na Universidade Federal da Bahia (UFBA, envolvendo o conteúdo da física universitária básica. Nesta experiência, os conteúdos foram estruturados em bases históricas, pelo menos em sua maior parte, e ministrados através das disciplinas Físicas Básicas I, II, III e IV, segundo uma abordagem simultaneamente histórica, fenomenológica (experimental, matemática e conceitual. Estas disciplinas são oferecidas paralelamente às tradicionais Físicas Gerais e Experimentais I, II, III e IV, que são destinadas aos alunos da área de ciências exatas, inclusive aos alunos da Licenciatura em Física, noturno.

Overlooked Talent Sources and Corporate Strategies for Affirmative Action. Part II

Science.gov (United States)

Iacobelli, John L.; Muczyk, Jan P.

1975-01-01

Part Two of the two-part article describes corporate strategies for affirmative action in order to obtain the most qualified individuals available for professional positions among minority and female candidates. (Author/BP)

49 CFR Appendix II to Part 805 - Employees Required To Submit Statements

Science.gov (United States)

2010-10-01

...—Employees Required To Submit Statements Statements of employment and financial interests are required of the... 49 Transportation 7 2010-10-01 2010-10-01 false Employees Required To Submit Statements II...) Office of the managing director: (1) Legislative affairs officer. (2) Program analysis officer. (d...

Radioactivity measurements in Europe after the Chernobyl accident. Part II: Fallout and deposition

International Nuclear Information System (INIS)

De Cort, M.; Graziani, G.; Raes, F.; Stanners, D.; Grippa, G.; Ricapito, I.

1990-01-01

The collection of deposition measurements, presented in this report and included in the floppy disk in the back cover has been put together as part of the REM programme (Radioactivity environmental Monitoring). This follows the compilation of air measurements (part 1) published previously (Raes, 1989). The objective of these compilations is to promote the integration of Chernobyl data on a European-wide basis to make them widely available in a coherent form for scientific study. Deposition measurements come in many forms (fallout, rain, soil) but all reflect the phenomena by which radionuclides in the air reach the surface. Depending on the manner of sampling, measurements can reflect integral values (e.g. from surface soil) or some fraction of the deposition (e.g. daily deposition using fallout or rain collectors). The latter can also be expressed as wet or dry according to the sampling apparatus used. The original sources of information from which this compilation was made vary widely : some of the data were obtained directly from floppy disks or tapes; others were copied manually from tables found in reports or papers in the scientific literature. The sets of measurements presented in this report were selected from this large patrimony of data in the REM data bank. Specific criteria were used to make this selection. Overall, only those data were used which had fully defined records. For daily deposition data actually sampled over 24 hourly periods were selected. With cumulative deposition care was taken to select data which covered the whole period of deposition marked by the passage of the cloud. The resulting data are presented on a unified format and as far as possible keep to individual measured values. In this manner the greatest flexibility is given to the user of this data

Biophysics and the microscopic theory of He II

International Nuclear Information System (INIS)

Chela-Flores, J.; Ghassib, H.B.

1985-08-01

Bose-Einstein condensation and solitonic propagation have recently been shown to be intimately related in biosystems. From our previous demonstration of the existence of solitons in a dilute Bose gas we set out the basis for a full microscopic theory of He II. This is used to understand recent experiments in He II, which are in apparent contradiction. New experiments are suggested by the microscopic theory. (author)

Técnicas de diagnóstico en transformadores a partir de su respuesta en el dominio de la frecuencia. Estado mundial del arte. Parte II; Techniques of Diagnostic in Transformers from their Answer in Frequency Domain. World State of the Art. Part II

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Orestes Hernández Areu

2011-02-01

Full Text Available Entre los métodos para el diagnóstico de transformadores de potencia se encuentran los métodos de detecciónde averías a través del llamado análisis de la respuesta en la frecuencia (FRA. En un artículo anterior, sepresentó la primera parte del estudio que se ha realizado del estado mundial del arte sobre las técnicas dediagnóstico de transformadores a partir de su respuesta en el dominio de la frecuencia y empleando latransformada rápida de Fourier (FFT. Esta segunda parte, trata específicamente, sobre los métodos dediagnóstico de transformadores mediante el análisis de la respuesta a un barrido de frecuencia (SFRA, sin lautilización de  la transformada rápida de Fourier (FFT.  In the methods for the diagnosis of power transformers there are the failure detection methods called frequencyresponse analysis (FRA. In a previous article, the first part of a study that has been carried out about theworld art state on the techniques of diagnostic in transformers from its response in the frequency domain andusing the fast Fourier transformed (FFT, was presented.This second part, tries specifically about the methodsof diagnostic of transformers by means of the sweeping frequency response analysis (SFRA, without usingthe fast Fourier tansformed (FFT.

48 CFR 14.201-3 - Part II-Contract clauses.

Science.gov (United States)

2010-10-01

... CONTRACTING METHODS AND CONTRACT TYPES SEALED BIDDING Solicitation of Bids 14.201-3 Part II—Contract clauses... law or by this regulation and any additional clauses expected to apply to any resulting contract, if...

GSTARS computer models and their applications, Part II: Applications

Science.gov (United States)

Simoes, F.J.M.; Yang, C.T.

2008-01-01

In part 1 of this two-paper series, a brief summary of the basic concepts and theories used in developing the Generalized Stream Tube model for Alluvial River Simulation (GSTARS) computer models was presented. Part 2 provides examples that illustrate some of the capabilities of the GSTARS models and how they can be applied to solve a wide range of river and reservoir sedimentation problems. Laboratory and field case studies are used and the examples show representative applications of the earlier and of the more recent versions of GSTARS. Some of the more recent capabilities implemented in GSTARS3, one of the latest versions of the series, are also discussed here with more detail. ?? 2008 International Research and Training Centre on Erosion and Sedimentation and the World Association for Sedimentation and Erosion Research.

Lisímetro de pesagem de grande porte. parte II: consumo hídrico do coqueiro anão verde irrigado Large-scale weighing lysimeter. part II: water requirements of the irrigated dwarf-green coconut

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Inajá F. Sousa

2011-05-01

Full Text Available Este trabalho, como segunda parte de uma pesquisa realizada no Estado de Sergipe, objetiva determinar a evapotranspiração e o coeficiente de cultura na fase de crescimento do coqueiro anão-verde (Cocos nucifera L., com base em medições lisimétricas e no modelo do balanço de energia, segundo a razão de Bowen. Obteve-se a evapotranspiração de referência pelo método de Penman-Monteith, na escala diária em todo o período experimental. O sistema de aquisição de dados foi programado para a automação da coleta de todos os sensores necessários à obtenção dos componentes do balanço de energia. O consumo hídrico do coqueiro durante a fase de crescimento é de 1.263,30 mm, com média diária de 3,90 mm d-1. O coeficiente de cultura nessa fase fenológica da palmeira varia entre 0,50 e 1,80, com média de 0,96.This paper, as Part II of a research carried out in Sergipe state, aims to determine evapotranspiration and crop coefficient of dwarf-green coconut (Cocos nucifera L. based on lysimeter measurements and Bowen ratio-energy balance method. The reference evapotranspiration was obtained by the Penman-Monteith approach on daily-scale during the experimental period. The data acquisition system was used to obtain all data from the sensors necessary to determine the energy balance components. The water requirements of coconut palm during the phenological growth stage is 1263.30 mm, with daily average of 3.90 mm d-1. The crop coefficient during this phenological growth stage varies between 0.50 and 1.80, with daily mean of 0.96.

Gefitinib plus cisplatin and radiotherapy in previously untreated head and neck squamous cell carcinoma: A phase II, randomized, double-blind, placebo-controlled study

International Nuclear Information System (INIS)

Gregoire, Vincent; Hamoir, Marc; Chen Changhu; Kane, Madeleine; Kawecki, Andrzej; Julka, Pramod K.; Wang, Hung-Ming; Prasad, Srihari; D'Cruz, Anil K.; Radosevic-Jelic, Ljiljana; Kumar, Rejnish R.; Korzeniowski, Stanislaw; Fijuth, Jacek; Machiels, Jean-Pascal; Sellers, Mark V.; Tchakov, Ilian; Raben, David

2011-01-01

Background and purpose: To assess the efficacy and safety of gefitinib given concomitantly and/or as maintenance therapy to standard cisplatin/radiotherapy for previously untreated, unresected, stage III/IV non-metastatic SCCHN. Materials and methods: In this phase II, double-blind, study, 226 patients were randomized to gefitinib 250 mg/day, 500 mg/day or placebo in two phases: a concomitant phase (gefitinib or placebo with chemoradiotherapy), followed by a maintenance phase (gefitinib or placebo alone). Primary endpoint was local disease control rate (LDCR) at 2 years; secondary endpoints were LDCR at 1 year, objective response rate, progression-free survival, overall survival, and safety and tolerability. Results: Gefitinib (250 and 500 mg/day) did not improve 2-year LDCR compared with placebo either when given concomitantly with chemoradiotherapy (32.7% vs. 33.6%, respectively; OR 0.921, 95% CI 0.508, 1.670 [1-sided p = 0.607]) or as maintenance therapy (28.8% vs. 37.4%, respectively; OR 0.684, 95% CI 0.377, 1.241 [1-sided p = 0.894]). Secondary efficacy outcomes were broadly consistent with the 2-year LDCR results. In both doses, gefitinib was well-tolerated and did not adversely affect the safety and tolerability of concomitant chemoradiotherapy. Conclusion: Gefitinib was well-tolerated, but did not improve efficacy compared with placebo when given concomitantly with chemoradiotherapy, or as maintenance therapy alone.

Modelling Zn(II) sorption onto clayey sediments using a multi-site ion-exchange model

International Nuclear Information System (INIS)

Tertre, E.; Beaucaire, C.; Coreau, N.; Juery, A.

2009-01-01

In environmental studies, it is necessary to be able to predict the behaviour of contaminants in more or less complex physico-chemical contexts. The improvement of this prediction partly depends on establishing thermodynamic models that can describe the behaviour of these contaminants and, in particular, the sorption reactions on mineral surfaces. In this way, based on the mass action law, it is possible to use surface complexation models and ion exchange models. Therefore, the aim of this study is (i) to develop an ion-exchange model able to describe the sorption of transition metal onto pure clay minerals and (ii) to test the ability of this approach to predict the sorption of these elements onto natural materials containing clay minerals (i.e. soils/sediments) under various chemical conditions. This study is focused on the behaviour of Zn(II) in the presence of clayey sediments. Considering that clay minerals are cation exchangers containing multiple sorption sites, it is possible to interpret the sorption of Zn(II), as well as competitor cations, by ion-exchange equilibria with the clay minerals. This approach is applied with success to interpret the experimental data obtained previously in the Zn(II)-H + -Na + -montmorillonite system. The authors' research team has already studied the behaviour of Na + , K + , Ca 2+ and Mg 2+ versus pH in terms of ion exchange onto pure montmorillonite, leading to the development of a thermodynamic database including the exchange site concentrations associated with montmorillonite and the selectivity coefficients of Na + , K + , Ca 2+ , Mg 2+ , and Zn 2+ versus H + . In the present study, experimental isotherms of Zn(II) on two different sediments in batch reactors at different pH and ionic strengths, using NaCl and CaSO 4 as electrolytes are reported. Assuming clay minerals are the main ion-exchanging phases, it is possible to predict Zn(II) sorption onto sediments under different experimental conditions, using the previously

Complexes of cobalt(II), nickel(II), copper(II), zinc(II), cadmium(II) and dioxouranium(II) with thiophene-2-aldehydethiosemicarbazone

International Nuclear Information System (INIS)

Singh, Balwan; Misra, Harihar

1986-01-01

Metal complexes of thiosemicarbazides have been known for their pharmacological applications. Significant antitubercular, fungicidal and antiviral activities have been reported for thiosemicarbazides and their derivatives. The present study describes the systhesis and characterisation of complexes of Co II , Cu II , Zn II ,Cd II and UO II with thiosemicarbazone obtained by condensing thiophene-2-aldehyde with thiosemicarbazide. 17 refs., 2 tables. (author)

AUTOMOTIVE DIESEL MAINTENANCE 2. UNIT XV, UNDERSTANDING DC GENERATOR PRINCIPLES (PART II).

Science.gov (United States)

Human Engineering Inst., Cleveland, OH.

THIS MODULE OF A 25-MODULE COURSE IS DESIGNED TO DEVELOP AN UNDERSTANDING OF MAINTENANCE PROCEDURES FOR DIRECT CURRENT GENERATORS USED ON DIESEL POWERED EQUIPMENT. TOPICS ARE SPECIAL GENERATOR CIRCUITS, GENERATOR TESTING, AND GENERATOR POLARITY. THE MODULE CONSISTS OF A SELF-INSTRUCTIONAL PROGRAMED TRAINING FILM "DC GENERATORS II--GENERATOR…

Transition metal complexes with thiosemicarbazide-based ligands. Part 60. Reactions of copper(II bromide with pyridoxal S-methylisothiosemicarbazone (PLITSC. Crystal structure of [Cu(PLITSC−HH2O]Br•H2O

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Leovac Vukadin M.

2014-01-01

Full Text Available The synthesis and structural characterization of a square-planar copper(II complex with pyridoxal S-methylisothiosemicarbazone (PLITSC of the formula [Cu(PLITSC−HH2O]Br•H2O (1 as the first Cu(II complex with monoanionic form of this ligand were described. Complex 1 together with two previously synthesized complexes [Cu(PLITSCBr2] (2 and [Cu(PLITSCBr(MeOH]Br (3 were characterized by elemental analysis, IR and electronic spectra and also by the methods of thermal analysis, conductometry and magnetochemistry. [Projekat Pokrajisnkog sekretarijata za nauku i tehnoloski razvoj Vojvodine i Ministarstva nauke Republike Srbije, br. 172014

Influence of previous breast surgery in sentinel lymph node biopsy in patients with breast cancer.

Science.gov (United States)

López-Prior, V; Díaz-Expósito, R; Casáns Tormo, I

The aim of this study was to review the feasibility of selective sentinel lymph node biopsy in patients with previous surgery for breast cancer, as well as to examine the factors that may interfere with sentinel node detection. A retrospective review was performed on 91 patients with breast cancer and previous breast surgery, and who underwent sentinel lymph node biopsy. Patients were divided into two groups according to their previous treatment: aesthetic breast surgery in 30 patients (group I) and breast-conserving surgery in 61 (group II). Lymphoscintigraphy was performed after an intra-tumour injection in 21 cases and a peri-areolar injection in 70 cases. An analysis was made of lymphatic drainage patterns and overall sentinel node detection according to clinical, pathological and surgical variables. The overall detection of the sentinel lymph node in the lymphoscintigraphy was 92.3%, with 7.7% of extra-axillary drainages. The identification rate was similar after aesthetic breast surgery (93.3%) and breast-conserving surgery (91.8%). Sentinel lymph nodes were found in the contralateral axilla in two patients (2.2%), and they were included in the histopathology study. The non-identification rate in the lymphoscintigraphy was 7.7%. There was a significantly higher non-detection rate in the highest histological grade tumours (28.6% grade III, 4.5% grade I and 3.6% grade II). Sentinel lymph node biopsy in patients with previous breast surgery is feasible and deserves further studies to assess the influence of different aspects in sentinel node detection in this clinical scenario. A high histological grade was significantly associated with a lower detection. Copyright © 2017 Elsevier España, S.L.U. y SEMNIM. All rights reserved.

The 12-item World Health Organization Disability Assessment Schedule II (WHO-DAS II: a nonparametric item response analysis

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Fernandez Ana

2010-05-01

Full Text Available Abstract Background Previous studies have analyzed the psychometric properties of the World Health Organization Disability Assessment Schedule II (WHO-DAS II using classical omnibus measures of scale quality. These analyses are sample dependent and do not model item responses as a function of the underlying trait level. The main objective of this study was to examine the effectiveness of the WHO-DAS II items and their options in discriminating between changes in the underlying disability level by means of item response analyses. We also explored differential item functioning (DIF in men and women. Methods The participants were 3615 adult general practice patients from 17 regions of Spain, with a first diagnosed major depressive episode. The 12-item WHO-DAS II was administered by the general practitioners during the consultation. We used a non-parametric item response method (Kernel-Smoothing implemented with the TestGraf software to examine the effectiveness of each item (item characteristic curves and their options (option characteristic curves in discriminating between changes in the underliying disability level. We examined composite DIF to know whether women had a higher probability than men of endorsing each item. Results Item response analyses indicated that the twelve items forming the WHO-DAS II perform very well. All items were determined to provide good discrimination across varying standardized levels of the trait. The items also had option characteristic curves that showed good discrimination, given that each increasing option became more likely than the previous as a function of increasing trait level. No gender-related DIF was found on any of the items. Conclusions All WHO-DAS II items were very good at assessing overall disability. Our results supported the appropriateness of the weights assigned to response option categories and showed an absence of gender differences in item functioning.

Angiotensin II and Renal Tubular Ion Transport

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Patricia Valles

2005-01-01

Evidence for the regulation of H+-ATPase activity in vivo and in vitro by trafficking/exocytosis has been provided. An additional level of H+-ATPase regulation via protein synthesis may be important as well. Recently, we have shown that both aldosterone and angiotensin II provide such a mechanism of regulation in vivo at the level of the medullary collecting tubule. Interestingly, in this part of the nephron, the effects of aldosterone and angiotensin II are not sodium dependent, whereas in the cortical collecting duct, both aldosterone and angiotensin II, by contrast, affect H+ secretion by sodium-dependent mechanisms.

Quality control of outpatient imaging examinations in North Rhine-Westphalia. Part II

International Nuclear Information System (INIS)

Krug, B.; Boettge, M.; Zaehringer, M.; Reinecke, T.; Coburger, S.; Harnischmacher, U.; Luengen, M.; Lauterbach, K.W.; Lehmacher, W.; Lackner, K.

2003-01-01

Purpose: In the state of North Rhine-Westphalia (NRW), Germany, a survey was conducted on radiologic examinations ordered by general practitioners (GPs). Part II of this study aims to determine the quality of the process and outcome. The reference standard is the assessment of both radiologists and physicians without board certification in radiology working at a university hospital and in outpatient facilities. Materials and Methods: All GPs in NRW were asked to cooperate. Participating GPs filled out a questionnaire for each patient. The patients recorded the symptoms prompting the imaging examinations. The radiologists or other physicians performing the examinations were asked to provide the images and written reports and to complete a questionnaire. A file was created for each of the 394 patients with image documentation of at least one examination. Each file, which included medical history, physical findings, imaging documentation and written report, was sequentially forwarded to a board-certified radiologist and to a physician without board certification in radiology working in a university hospital and in an outpatient facility. All physicians were requested to complete a structured questionnaire for each file. Results: The referral diagnoses were rated as medically plausible in 81%, the indications for imaging found correct in 76%, the examination techniques considered appropriate in 69%, the clinical question answered in 63%, the interpretation judged medically correct in 50% and all incidental findings documented in 49%. In retrospect, 32% of the examinations were judged superfluous. The sequence of multiple examinations performed on a particular patient was rated as appropriate in 51%. The interpretation revealed specialty-related differences. The plausibility of the referral diagnoses had a significant impact on the appropriateness of subsequent diagnostic investigations. Marked deficits showed sonography, performance by non-radiologists, self

The part task of the part-spacing paradigm is not a pure measurement of part-based information of faces.

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Qi Zhu

Full Text Available BACKGROUND: Faces are arguably one of the most important object categories encountered by human observers, yet they present one of the most difficult challenges to both the human and artificial visual systems. A variety of experimental paradigms have been developed to study how faces are represented and recognized, among which is the part-spacing paradigm. This paradigm is presumed to characterize the processing of both the featural and configural information of faces, and it has become increasingly popular for testing hypotheses on face specificity and in the diagnosis of face perception in cognitive disorders. METHODOLOGY/PRINCIPAL FINDINGS: In two experiments we questioned the validity of the part task of this paradigm by showing that, in this task, measuring pure information about face parts is confounded by the effect of face configuration on the perception of those parts. First, we eliminated or reduced contributions from face configuration by either rearranging face parts into a non-face configuration or by removing the low spatial frequencies of face images. We found that face parts were no longer sensitive to inversion, suggesting that the previously reported inversion effect observed in the part task was due in fact to the presence of face configuration. Second, self-reported prosopagnosic patients who were selectively impaired in the holistic processing of faces failed to detect part changes when face configurations were presented. When face configurations were scrambled, however, their performance was as good as that of normal controls. CONCLUSIONS/SIGNIFICANCE: In sum, consistent evidence from testing both normal and prosopagnosic subjects suggests the part task of the part-spacing paradigm is not an appropriate task for either measuring how face parts alone are processed or for providing a valid contrast to the spacing task. Therefore, conclusions from previous studies using the part-spacing paradigm may need re-evaluation with

A two-point diagnostic for the H II galaxy Hubble diagram

Science.gov (United States)

Leaf, Kyle; Melia, Fulvio

2018-03-01

A previous analysis of starburst-dominated H II galaxies and H II regions has demonstrated a statistically significant preference for the Friedmann-Robertson-Walker cosmology with zero active mass, known as the Rh = ct universe, over Λcold dark matter (ΛCDM) and its related dark-matter parametrizations. In this paper, we employ a two-point diagnostic with these data to present a complementary statistical comparison of Rh = ct with Planck ΛCDM. Our two-point diagnostic compares, in a pairwise fashion, the difference between the distance modulus measured at two redshifts with that predicted by each cosmology. Our results support the conclusion drawn by a previous comparative analysis demonstrating that Rh = ct is statistically preferred over Planck ΛCDM. But we also find that the reported errors in the H II measurements may not be purely Gaussian, perhaps due to a partial contamination by non-Gaussian systematic effects. The use of H II galaxies and H II regions as standard candles may be improved even further with a better handling of the systematics in these sources.

TRUPACT-II, a regulatory perspective

International Nuclear Information System (INIS)

Gregory, P.C.; Spooner, O.R.

1995-01-01

The Transuranic Package Transporter II (TRUPACT-II) is a US Nuclear Regulatory Commission (NRC) certified Type B packaging for the shipment of contact-handled transuranic (CH-TRU) material by the US Department of Energy (DOE). The NRC approved the TRUPACT-II design as meeting the requirements of Title 10, Code of Federal Regulations, Part 71 (10 CFR 71) and issued Certificate of Compliance (CofC) Number 9218 to the DOE. There are currently 15 certified TRUPACT-IIs. Additional TRUPACT-IIs will be required to make more than 15,000 shipments of CH-TRU waste to the Waste Isolation Pilot Plant (WIPP) site near Carlsbad, New Mexico. The TRUPACT-II may also be used for the DOE inter-site and intra-site shipments of CH-TRU waste. The Land Withdrawal Act (Public Law 102-579), enacted by the US Congress, October 30, 1992, and an agreement between the DOE and the State of New Mexico, signed August 4, 1987, both stipulate that only NRC approved packaging may be used for shipments of TRU waste to the WIPP. Early in the TRUPACT-II development phase it was decided that the transportation system (tractor, trailer, and TRUPACT-II) should be highway legal on all routes without the need for oversize and/or overweight permits. In large measure, public acceptance of the DOE's efforts to safely transport CH-TRU waste depends on the public's perception that the TRUPACT-II is in compliance with all applicable regulations, standards, and quality assurance requirements. This paper addresses some of the numerous regulations applicable to Type B packaging, and it describes how the TRUPACT-II complies with these regulations

Sustainable gasification–biochar systems? A case-study of rice-husk gasification in Cambodia, Part II: Field trial results, carbon abatement, economic assessment and conclusions

International Nuclear Information System (INIS)

Shackley, Simon; Carter, Sarah; Knowles, Tony; Middelink, Erik; Haefele, Stephan; Haszeldine, Stuart

2012-01-01

In part I we described the gasification technology and characterised the physio-chemical properties and environmental impacts of the rice husk char (RHC) by-product. In part II we present summary results from field trials using the RHC, and provide an estimate of the carbon abatement and economic evaluation of the system. Statistically significant yield increases are demonstrated for RHC addition in irrigated rice cultivation (33% increase in paddy rice yield for a 41.5 t (dry weight) RHC application per hectare). The carbon abatement from the RHC addition is approximately 0.42 t CO 2 t −1 rice husk; including energy generation from gasification this increases to ca. 0.86 tCO 2 t −1 . Assuming a carbon value of $5 t CO 2 t −1 , and agronomic value of $3 t −1 RHC based on the field trials, the economic value of the RHC varies from $9 t −1 (including only recalcitrant carbon) to $15 t −1 (including avoided emissions from energy production). We summarise results from parts I and II, concluding that the gasification–biochar system meets many of the criteria of sustainability, but requires better waste water management and more field trials to demonstrate repeatable agronomic efficacy of RHC application. - Highlights: ► Field trials show statistically significant rice yield increases using rice husk char (RHC). ► Carbon abatement of 0.42 t CO 2 t −1 rice husk from RHC production. ► Bioenergy generation via gasification gives carbon abatement of 0.44 t CO 2 t −1 husk. ► Total carbon abatement is therefore ca. 0.86 t CO 2 t −1 husk. ► Agronomic value from trials is $3 t −1 char; assuming $5 CO 2 t −1 , the total value of RHC is $9–$15 t −1 .

European Nuclear Decommissioning Training Facility II

International Nuclear Information System (INIS)

Demeulemeester, Y.

2005-01-01

SCK-CEN co-ordinates a project called European Nuclear Decommissioning Training Facility II (EUNDETRAF II) in the Sixth Framework Programme on Community activities in the field of research, technological development and demonstration for the period 2002 to 2006. This was a continuation of the FP5 project EUNDETRAF. EUNDETRAF II is a consortium of main European decommissioners, such as SCK-CEN, EWN (Energie Werke Nord, Greifswald Germany), Belgatom (Belgium), SOGIN Societa Gestione Impiantio Nucleari, Italy), Universitaet Hannover (Germany), RWE NUKEM (United Kingdom), DECOM Slovakia Slovakia), CEA Centre d'Energie Atomique, France), UKAEA (United Kingdom's Atomic Energy Agency, United Kingdom) and NRG (Nuclear Research and consultancy Group, Netherlands). The primary objective of this project is to bring together this vast skill base and experience; to consolidate it for easy assimilation and to transfer to future generations by organising a comprehensive training programme.Each training course has a one-week theoretical and a one-week practical component. The theoretical part is for a broader audience and consists of lectures covering all the main aspects of a decommissioning. The practical part of the course includes site visits and desk top solutions of anticipated decommissioning problems. Due to operational constraints and safety considerations, the number of participants to this part of the course is strictly limited. The partners intend to organise altogether two two-week EUNDETRAF II training courses over a period of three years. Another goal is to disseminate the existing theory as well as the practical know-how to personnel of the third countries. Finally it is important to bring together the principal decommissioning organisations undertaking various decommissioning activities. The project creates a forum for regular contacts to exchange information and experiences for mutual benefit of these organisations as well as to enhance skill base in Europe to

Testing and Analysis of a Composite Non-Cylindrical Aircraft Fuselage Structure . Part II; Severe Damage

Science.gov (United States)

Przekop, Adam; Jegley, Dawn C.; Lovejoy, Andrew E.; Rouse, Marshall; Wu, Hsi-Yung T.

2016-01-01

The Environmentally Responsible Aviation Project aimed to develop aircraft technologies enabling significant fuel burn and community noise reductions. Small incremental changes to the conventional metallic alloy-based 'tube and wing' configuration were not sufficient to achieve the desired metrics. One airframe concept identified by the project as having the potential to dramatically improve aircraft performance was a composite-based hybrid wing body configuration. Such a concept, however, presented inherent challenges stemming from, among other factors, the necessity to transfer wing loads through the entire center fuselage section which accommodates a pressurized cabin confined by flat or nearly flat panels. This paper discusses a finite element analysis and the testing of a large-scale hybrid wing body center section structure developed and constructed to demonstrate that the Pultruded Rod Stitched Efficient Unitized Structure concept can meet these challenging demands of the next generation airframes. Part II of the paper considers the final test to failure of the test article in the presence of an intentionally inflicted severe discrete source damage under the wing up-bending loading condition. Finite element analysis results are compared with measurements acquired during the test and demonstrate that the hybrid wing body test article was able to redistribute and support the required design loads in a severely damaged condition.

Mn(II), Zn(II) and VO(II) Schiff

Indian Academy of Sciences (India)

Home; Journals; Journal of Chemical Sciences; Volume 113; Issue 3. Synthesis and characterisation of Cu(II), Ni(II), Mn(II), Zn(II) and VO(II) Schiff base complexes derived from o-phenylenediamine and acetoacetanilide. N Raman Y Pitchaikani Raja A Kulandaisamy. Inorganic Volume 113 Issue 3 June 2001 pp 183-189 ...

Isolation and partial characterisation of a mammalian cell mutant hypersensitive to topoisomerase II inhibitors and X-rays

International Nuclear Information System (INIS)

Davies, S.M.; Davies, S.L.; Hickson, I.D.; Hall, A.G.

1990-01-01

The authors have isolated, following one-step mutagenesis, a Chinese hamster ovary cell mutant hypersensitive to the intercalating agent, adriamycin. This agent exerts at least part of its cytotoxic action via inhibition of the nuclear enzyme, topoisomerase II. The mutant, designated ADR-3, showed hypersensitivity to all classes of topoisomerase II inhibitors, inlcuding actinomycin D, amsacrine (m-AMSA), etoposide (VP16) and mitoxantrone. ADR-3 cells also showed cross-sensitivity to ionizing radiation, but not no UV light. Topoisomerase II activity was elevated to a small but significant degree in ADR-3 cells, and this was reflected in a 1.5-fold higher level of topoisomerase II protein in ADR-3 than in CHO-K1 cells, as judged by Western blotting. ADR-3 cells were hypersensitive to cumene hydroperoxide but cross-resistant to hydrogen peroxide, suggesting possible abnormality in the detoxification of peroxides by glutathione peroxidase or catalase. Glutathione peroxidase activity against hydroperoxide was elevated to a small but significant extent in mutant cells. Catalase levels were not significantly different in ADR-3 and CHO-K1 cells. ADR-3 cells were recessive in hybrids with parental CHO-K1 cells with respect to sensitivity to topoisomerase II inhibitors and X-rays, and represent a different genetic complementation group from the previously reported adriamycin-sensitive mutant, ADR-1. (author). 34 refs.; 5 figs.; 3 tabs

Human insulin-like growth factor II leader 2 mediates internal initiation of translation

DEFF Research Database (Denmark)

Pedersen, Susanne; Christiansen, Jan; Hansen, T.O.

2002-01-01

Insulin-like growth factor II (IGF-II) is a fetal growth factor, which belongs to the family of insulin-like peptides. During fetal life, the IGF-II gene generates three mRNAs with different 5' untranslated regions (UTRs), but identical coding regions and 3' UTRs. We have shown previously that IG...

Psychiatric emergencies (part II): psychiatric disorders coexisting with organic diseases.

Science.gov (United States)

Testa, A; Giannuzzi, R; Sollazzo, F; Petrongolo, L; Bernardini, L; Dain, S

2013-02-01

In this Part II psychiatric disorders coexisting with organic diseases are discussed. "Comorbidity phenomenon" defines the not univocal interrelation between medical illnesses and psychiatric disorders, each other negatively influencing morbidity and mortality. Most severe psychiatric disorders, such as schizophrenia, bipolar disorder and depression, show increased prevalence of cardiovascular disease, related to poverty, use of psychotropic medication, and higher rate of preventable risk factors such as smoking, addiction, poor diet and lack of exercise. Moreover, psychiatric and organic disorders can develop together in different conditions of toxic substance and prescription drug use or abuse, especially in the emergency setting population. Different combinations with mutual interaction of psychiatric disorders and substance use disorders are defined by the so called "dual diagnosis". The hypotheses that attempt to explain the psychiatric disorders and substance abuse relationship are examined: (1) common risk factors; (2) psychiatric disorders precipitated by substance use; (3) psychiatric disorders precipitating substance use (self-medication hypothesis); and (4) synergistic interaction. Diagnostic and therapeutic difficulty concerning the problem of dual diagnosis, and legal implications, are also discussed. Substance induced psychiatric and organic symptoms can occur both in the intoxication and withdrawal state. Since ancient history, humans selected indigene psychotropic plants for recreational, medicinal, doping or spiritual purpose. After the isolation of active principles or their chemical synthesis, higher blood concentrations reached predispose to substance use, abuse and dependence. Abuse substances have specific molecular targets and very different acute mechanisms of action, mainly involving dopaminergic and serotoninergic systems, but finally converging on the brain's reward pathways, increasing dopamine in nucleus accumbens. The most common

Value of flexible resources, virtual bidding, and self-scheduling in two-settlement electricity markets with wind generation - Part II: ISO Models and Application

DEFF Research Database (Denmark)

Kazempour, Jalal; Hobbs, Benjamin F.

2017-01-01

In Part II of this paper, we present formulations for three two-settlement market models: baseline cost-minimization (Stoch-Opt); and two sequential market models in which an independent system operator (ISO) runs real-time (RT) balancing markets after making day-ahead (DA) generating unit...... commitment decisions based upon deterministic wind forecasts, while virtual bidders arbitrage the two markets (Seq and SeqSS). The latter two models differ in terms of whether some slow-start generators can self-schedule in the DA market while anticipating probabilities of RT prices. Models in Seq and Seq......-SS build on components of the two-settlement equilibrium model (Stoch-MP) defined in Part I of this paper [1]. We then provide numerical results for all four models. A simple single-node case illustrates the economic impacts of flexibility, virtual bidding, and self-schedules, and is followed by a larger...

PIO I-II tendencies case study. Part 1. Mathematical modeling

Directory of Open Access Journals (Sweden)

Adrian TOADER

2010-03-01

Full Text Available In the paper, a study is performed from the perspective of giving a method to reduce the conservatism of the well known PIO (Pilot-Induced Oscillation criteria in predicting the susceptibility of an aircraft to this very harmful phenomenon. There are three interacting components of a PIO – the pilot, the vehicle, and the trigger (in fact, the hazard. The study, conceived in two parts, aims to underline the importance of human pilot model involved in analysis. In this first part, it is shown, following classical sources, how the LQG theory of control and estimation is used to obtain a complex model of human pilot. The approach is based on the argument, experimentally proved, that the human behaves “optimally” in some sense, subject to his inherent psychophysical limitations. The validation of such model is accomplished based on the experimental model of a VTOL-type aircraft. Then, the procedure of inserting typical saturation nonlinearities in the open loop transfer function is presented. A second part of the paper will illustrate PIO tendencies evaluation by means of a grapho-analytic method.

Developing of risk-hedging CO2-emission policy. Part II: risks associated with measures to limit emissions, synthesis and conclusions

International Nuclear Information System (INIS)

Harvey, L.D.D.

1996-01-01

This paper is Part II of a two-part series in which the risk associated with unrestrained greenhouse-gas emissions, and with measures to limit emissions, are reviewed. The following risks associated with these efforts to limit CO 2 emissions are reviewed here: (1) resources might be diverted from other urgent needs; (2) economic growth might be reduced; (3) reduction measures might cost more than expected; (4) early action might cost more than later action; (5) reduction measures might have undesired side effects; (6) reduction measures might require heavy-handed government intervention; and (7) reduction measures might not work. With gradual implementation of a diversified portfolio of measures, these risks can be greatly reduced. Based on the review of risks associated with measures to limit emissions here, and the review of the risk associated with unrestrained emissions presented in Part I, it is concluded that a reasonable near-term (20-30 year) risk hedging strategy is one which seeks to stabilize global fossil CO 2 emissions at the present (early 1990s) level. This is turn implies an emission reduction of 26% for industrialized countries as a whole and 40-50% for Canada and the USA if developing country emissions are to increase by no more than 60%, which in itself would require major assistance from the industrialized countries. The framework and conclusions presented here are critically compared with so-called optimization frameworks. 82 refs., 2 figs., 2 tabs

Stability Improvement of High-Pressure-Ratio Turbocharger Centrifugal Compressor by Asymmetrical Flow Control-Part II: Nonaxisymmetrical Self-Recirculation Casing Treatment.

Science.gov (United States)

Zheng, Xinqian; Zhang, Yangjun; Yang, Mingyang; Bamba, Takahiro; Tamaki, Hideaki

2013-03-01

This is part II of a two-part paper involving the development of an asymmetrical flow control method to widen the operating range of a turbocharger centrifugal compressor with high-pressure ratio. A nonaxisymmetrical self-recirculation casing treatment (SRCT) as an instance of asymmetrical flow control method is presented. Experimental and numerical methods were used to investigate the impact of nonaxisymmetrical SRCT on the surge point of the centrifugal compressor. First, the influence of the geometry of a symmetric SRCT on the compressor performance was studied by means of numerical simulation. The key parameter of the SRCT was found to be the distance from the main blade leading edge to the rear groove (S r ). Next, several arrangements of a nonaxisymmetrical SRCT were designed, based on flow analysis presented in part I. Then, a series of experiments were carried out to analyze the influence of nonaxisymmetrical SRCT on the compressor performance. Results show that the nonaxisymmetrical SRCT has a certain influence on the performance and has a larger potential for stability improvement than the traditional symmetric SRCT. For the investigated SRCT, the surge flow rate of the compressor with the nonaxisymmetrical SRCTs is about 10% lower than that of the compressor with symmetric SRCT. The largest surge margin (smallest surge flow rate) can be obtained when the phase of the largest S r is coincident with the phase of the minimum static pressure in the vicinity of the leading edge of the splitter blades.

Mechanisms of Hg(II) uptake and methylation in methylating bacteria

Energy Technology Data Exchange (ETDEWEB)

Morel, Francois M. M. [Princeton Univ., NJ (United States). Geosciences

2016-10-14

The goal of this project was to understand the critical factors which control the availability and transport of Hg(II) into cells, a first step in the production of the neurotoxin, methylmercury. Specifically, this research focused on understanding the mechanism of bacterial mercury uptake and how mercury speciation affects the specificity and kinetics of mercury transport. Our research has shown that Hg(II) uptake in three different iron and sulfate-reducing proteobacteria occurs by the following mechanism (1) : Hg(II) uptake is an active transport process requiring energy, (2) it is dependent upon the structure of the Hg binding ligand, and (3) it is mediated by a heavy metal transporter such as one which transports the essential metal, Zn(II). In order to determine whether this mechanism extends to more diverse phylogenetic groups, we have begun examining Hg(II) uptake and bioavailability in two representative Hg methylating strains within the Firmicutes. These organisms have remarkably different membrane structures distinct from the Proteobacteria. Our results show low uptake rates in these two species of Firmicutes relative to the previously characterized Proteobacteria. This may explain the low methylation rates and yields observed in these organisms. Most surprisingly, however, these organisms appear to take up Hg(II) passively, as the addition of a protonophore failed to reduce Hg(II) uptake in these organisms. This is quite different to what has been observed previously for the Proteobacteria and suggests a different mechanism for Hg(II) uptake in the Firmicutes. We are continuing to understand and describe Hg(II) uptake in these organisms. A manuscript is expected to be submitted on this research in June 2016.

The PIP-II Reference Design Report

Energy Technology Data Exchange (ETDEWEB)

Lebedev, Valeri, [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); et al.

2015-06-01

The Proton Improvement Plan-II (PIP-II) is a high-intensity proton facility being developed to support a world-leading neutrino program over the next two decades at Fermilab. PIP-II is an integral part of the U.S. Intensity Frontier Roadmap as described in the Particle Physics Project Prioritization Panel (P5) report of May 2014 [1]. As an immediate goal PIP-II is focused on upgrades to the Fermilab accelerator complex capable of providing a beam power in excess of 1 MW on target at the initiation of LBNF [1,2] operations. PIP-II is a part of a longer-term concept for a sustained campaign of upgrades and improvements to achieve multi-MW capabilities at Fermilab. PIP-II is based on three major thrusts. They are (1) the recently completed upgrades to the Recycler and Main Injector (MI) for the NOvA experiment, (2) the Proton Improvement Plan [3] currently underway, and (3) the Project X Reference Design [4]. Note that: The Proton Improvement Plan (PIP) consolidates a set of improvements to the existing Linac, Booster, and Main Injector (MI) aimed at supporting 15 Hz Booster beam operation. In combination, the NOvA upgrades and PIP create a capability of delivering 700 kW beam power from the Main Injector at 120 GeV; The scope of the Project X Reference Design Report was aimed well beyond PIP. It described a complete concept for a multi-MW proton facility that could support a broad particle physics program based on neutrino, kaon, muon, and nucleon experiments [5,6]. The Project X conceptual design has evolved over a number of years, incorporating continuous input on physics research goals and advances in the underlying technology development programs [7,8,9]. PIP-II, to high degree, inherits these goals as the goals for future developments and upgrades. This document (PIP-II Reference Design Report) describes an initial step in the development of the Fermilab accelerating complex. The plan described in this Report balances the far-term goals of the Laboratory

Striking hematological abnormalities in patients with microcephalic osteodysplastic primordial dwarfism type II (MOPD II): a potential role of pericentrin in hematopoiesis.

Science.gov (United States)

Unal, Sule; Alanay, Yasemin; Cetin, Mualla; Boduroglu, Koray; Utine, Eda; Cormier-Daire, Valerie; Huber, Celine; Ozsurekci, Yasemin; Kilic, Esra; Simsek Kiper, Ozlem Pelin; Gumruk, Fatma

2014-02-01

Microcephalic osteodysplastic primordial dwarfism type II (MOPD II) is a rare primordial dwarfism that is similar to Seckel syndrome. Seckel syndrome is known to be associated with various hematological abnormalities; however, hematological findings in MOPD II patients have not been previously reported. The present study aimed to describe the hematological findings in a series of eight patients with MOPD II from a single center. The study included eight patients with MOPD II that were analyzed via molecular testing, and physical and laboratory examinations. Molecular testing showed that seven of the eight patients had pericentrin (PCNT) gene mutations. Hematological evaluation showed that 7 (87.5%) patients had thrombocytosis, 6 (75%) had leukocytosis, 5 (62.5%) had both leukocytosis and thrombocytosis, and 2 (25%) had anemia. We report leukocytosis and thrombocytosis as a common hematologic abnormality in patients with MOPD II. The present findings may improve our understanding of the potential function of the PCNT gene in hematopoietic cell proliferation and differentiation. © 2013 Wiley Periodicals, Inc.

Operation of industrial electrical substations. Part II: practical applications

Energy Technology Data Exchange (ETDEWEB)

Sanchez Jimenez, Juan J; Zerquera Izquierdo, Mariano D; Beltran Leon, Jose S; Garcia Martinez, Juan M; Alvarez Urena, Maria V; Meza Diaz, Guillermo [Universidad de Guadalajara (Mexico)]. E-mails: cheosj@yahoo.com; mdzi@hotmail.com; beltran5601@yahoo.com.mx; jmargarmtz@yahoo.com; victory_alvarez@telmexmail.com; depmec@cucei.udg.mx

2013-03-15

The practical application of the methodology explained in Part 1 in a Cuban industry is the principal objective of this paper. The calculus of the economical operation of the principal transformers of the industrial plant is shown of the one very easy form, as well as the determination of the equations of the losses when the transformers operate under a given load diagram. It is calculated the state load which will be passed to the operation in parallel. [Spanish] El objetivo principal de este trabajo es la aplicacion practica de la metodologia, en una industria cubana, que se explico en la Parte 1. El calculo de la operacion economica de los principales transformadores de la planta industrial se muestra de una forma muy facil, asi como la determinacion de las ecuaciones de las perdidas cuando los transformadores operan bajo un diagrama de carga dado. Se calcula la carga de estado que se pasa a la operacion en paralelo.

Adsorption of Pb(II), Cu(II), Cd(II), Zn(II), Ni(II), Fe(II), and As(V) on bacterially produced metal sulfides.

Science.gov (United States)

Jong, Tony; Parry, David L

2004-07-01

The adsorption of Pb(II), Cu(II), Cd(II), Zn(II), Ni(II), Fe(II) and As(V) onto bacterially produced metal sulfide (BPMS) material was investigated using a batch equilibrium method. It was found that the sulfide material had adsorptive properties comparable with those of other adsorbents with respect to the specific uptake of a range of metals and, the levels to which dissolved metal concentrations in solution can be reduced. The percentage of adsorption increased with increasing pH and adsorbent dose, but decreased with increasing initial dissolved metal concentration. The pH of the solution was the most important parameter controlling adsorption of Cd(II), Cu(II), Fe(II), Ni(II), Pb(II), Zn(II), and As(V) by BPMS. The adsorption data were successfully modeled using the Langmuir adsorption isotherm. Desorption experiments showed that the reversibility of adsorption was low, suggesting high-affinity adsorption governed by chemisorption. The mechanism of adsorption for the divalent metals was thought to be the formation of strong, inner-sphere complexes involving surface hydroxyl groups. However, the mechanism for the adsorption of As(V) by BPMS appears to be distinct from that of surface hydroxyl exchange. These results have important implications to the management of metal sulfide sludge produced by bacterial sulfate reduction.

Status of the GPD program rate at COMPASS II

Energy Technology Data Exchange (ETDEWEB)

Gorzellik, Matthias; Fischer, Horst; Joerg, Philipp; Koenigsmann, Kay; Landgraf, Steffen; Regali, Christopher; Schmidt, Katharina; Sirtl, Stefan; Szameitat, Tobias; Wolbeek, Johannes ter [Physikalisches Institut, Albert-Ludwigs-Universitaet Freiburg (Germany); Collaboration: COMPASS collaboration

2015-07-01

The COMPASS-II experiment is a fixed target experiment situated at CERN. A tertiary myon beam from the SPS scattered of protons from a liquid hydrogen target is used to measure Deeply Virtual Compton Scattering (DVCS) and Hard Exclusive Meson Production (HEMP). Both processes open a unique window to constrain Generalized Parton Distributions, which are related to the total angular momentum of quarks, antiquarks and gluons in the nucleon. An upgrade of the previous experiment was started in 2012. The major parts of the upgrade for the measurement of exclusive reactions are the recoil proton detector (CAMERA) and an additional Electromagnetic Calorimeter. The close to final setup allows for a measurement of exclusive reactions with very low cross sections in a wide kinematic range. A pilot run, covering five weeks of data taking, was performed at the end of 2012. In this talk we present first results from the analysis.

[Fe II] 1.64 μm FEATURES OF JETS AND OUTFLOWS FROM YOUNG STELLAR OBJECTS IN THE CARINA NEBULA

Energy Technology Data Exchange (ETDEWEB)

Shinn, Jong-Ho; Lee, Jae-Joon; Chun, Moo-Young; Lyo, A.-Ran; Moon, Dae-Sik; Kyeong, Jaemann; Park, Byeong-Gon [Korea Astronomy and Space Science Institute, 776 Daeduk-daero, Yuseong-gu, Daejeon 305-348 (Korea, Republic of); Pyo, Tae-Soo [Subaru Telescope, National Astronomical Observatory of Japan, 650 North A' ohōkū Place, Hilo, HI 96720 (United States); Lee, Ho-Gyu [Department of Astronomy, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Kim, Hyun-Jeong; Koo, Bon-Chul; Lee, Yong-Hyun [Department of Physics and Astronomy, Seoul National University, 599 Gwanangno, Gwanak-gu, Seoul 151-747 (Korea, Republic of); Sung, Hwankyung; Hur, Hyeonoh, E-mail: jhshinn@kasi.re.kr [Department of Astronomy and Space Science, Sejong University, 98 Kunja-dong, Kwangjin-gu, Seoul 143-747 (Korea, Republic of)

2013-11-01

We present [Fe II] 1.64 μm imaging observations for jets and outflows from young stellar objects (YSOs) over the northern part (∼24' × 45') of the Carina Nebula, a massive star-forming region. The observations were performed with IRIS2 of the Anglo-Australian Telescope and the seeing was ∼1.''5 ± 0.''5. Eleven jet and outflow features are detected at eight different regions and are termed ionized Fe objects (IFOs). One Herbig-Haro candidate that was missed in Hubble Space Telescope Hα observations is newly identified as HHc-16, referring to our [Fe II] images. IFOs have knotty or longish shapes, and the detection rate of IFOs against previously identified YSOs is 1.4%, which should be treated as a lower limit. Four IFOs show anti-correlated peak intensities in [Fe II] and Hα, where the ratio I([Fe II])/I(Hα) is higher for longish IFOs than for knotty IFOs. We estimate the outflow mass loss rate from the [Fe II] flux using two different methods. The jet-driving objects are identified for three IFOs (IFO-2, -4, and -7) for which we study the relations between the outflow mass loss rate and the YSO physical parameters from the radiative transfer model fitting. The ratios of the outflow mass loss rate over the disk accretion rate for IFO-4 and -7 are consistent with the previously reported values (10{sup –2}-10{sup +1}), while the ratio is higher for IFO-2. This excess may result from underestimating the disk accretion rate. The jet-driving objects are likely to be low- or intermediate-mass stars. Other YSO physical parameters, such as luminosity and age, show reasonable relations or trends.

COORDINATION COMPOUNDS OF NICKEL(II), COPPER(II) AND COBALT(II) BASED ON S-METHYLISOTHIOSEMICARBAZIDE AS DYES FOR THERMOPLASTIC POLYMERS

OpenAIRE

Ştefan Manole; Maria Cocu

2011-01-01

We have researched the color properties of coordination compounds synthesized by us previously [1] (8-(1',2'-naphthyl)-1- R3-methyl-6-thiomethyl-4,5,7-triazaocta-1,3,5,7-tetraenato-1,1'-diolato(-)O, O', N4, N7-M(II), where R=CH3, C6H5, M=Ni, Co, Cu), which can be used for coloring thermoplastic masses. They meet the requirements for use as a pigment for coloring thermoplastic masses.

Distribution of Si II in the Galactic center

Science.gov (United States)

Graf, P.; Herter, T.; Gull, G. E.; Houck, J. R.

1988-01-01

A map of the Galactic center region in the forbidden Si II 34.8-micron line is presented. The line emission arises from within the photodissociation region (PDR) associated with the neutral gas ring surrounding an ionized gas core confined within 2 pc of the Galactic center. Si II is a useful probe of the inner regions of the ring since it is always optically thin. The Si II data, when analyzed in conjunction with O I, C II, and molecular measurements, outlines the transition region between the PDR and the surrounding molecular cloud. The Si II emission is found to extend beyond that of the O II into the neutral gas ring. Although the interpretation is not unique, the data are consistent with a constant gas-phase abundance of silicon within the inner part of the PDR while the gaseous silicon is depleted by molecule formation in the transition region.

Immobilized Tannin from Sanseviera trifasciata on Carbon as Adsorbent For Iron(II in Polluted Water Source

Directory of Open Access Journals (Sweden)

Irfan Hanafi Arif

2016-03-01

Full Text Available The organic-agricultural waste resulted from local farmer or community gardening recently paid public attention. The presence and easily grown of “Lidah Mertua” or Sanseviera trifasciata being focused on potency investigation for its prospecting application. It was reported contain some phenolic and also tannin extracted from aqueous solvents. This paper revealed recent investigation applying of its isolated tannin from leave part to modifying of activated carbon. The previous report published that carbon were able to adsorb some toxic heavy metals. However, it has some limitation including lower capacity adsorption. Impregnated or immobilized the tannin-isolated from S. trifasciata leaves was able to modify the carbon functionality, physical appearance, pores size, and it adsorption capacity. Both Langmuir and Freundlich adsorption mechanism model also disclosed the developed adsorbent mechanism of iron(II adsorption on the adsorbent tannin-immobolized on carbon. The real test using community well drilling water source also gave important finding on the concentration of iron(II contained on water source.

As sure as tax, rain or death (Part II) : digitalisation dragons?

NARCIS (Netherlands)

Staal, Anne

2017-01-01

Tax evasion, delayed trains & untidy death seem to be parts of our daily lives. But what about the digitalisation dragons? Will they wipe away B2B sales and procurement as we know it, our will we see a more nuanced picture? The first Part on this topic so far has attracted 3700+ readers at our PSF

Lagrangian intersection Floer theory anomaly and obstruction, part II

CERN Document Server

Fukaya, Kenji; Ohta, Hiroshi; Ono, Kaoru

2009-01-01

This is a two-volume series research monograph on the general Lagrangian Floer theory and on the accompanying homological algebra of filtered A_\\infty-algebras. This book provides the most important step towards a rigorous foundation of the Fukaya category in general context. In Volume I, general deformation theory of the Floer cohomology is developed in both algebraic and geometric contexts. An essentially self-contained homotopy theory of filtered A_\\infty algebras and A_\\infty bimodules and applications of their obstruction-deformation theory to the Lagrangian Floer theory are presented. Volume II contains detailed studies of two of the main points of the foundation of the theory: transversality and orientation. The study of transversality is based on the virtual fundamental chain techniques (the theory of Kuranishi structures and their multisections) and chain level intersection theories. A detailed analysis comparing the orientations of the moduli spaces and their fiber products is carried out. A self-co...

Slag Behavior in Gasifiers. Part II: Constitutive Modeling of Slag

Energy Technology Data Exchange (ETDEWEB)

Massoudi, Mehrdad [National Energy Technology Laboratory; Wang, Ping

2013-02-07

The viscosity of slag and the thermal conductivity of ash deposits are among two of the most important constitutive parameters that need to be studied. The accurate formulation or representations of the (transport) properties of coal present a special challenge of modeling efforts in computational fluid dynamics applications. Studies have indicated that slag viscosity must be within a certain range of temperatures for tapping and the membrane wall to be accessible, for example, between 1,300 °C and 1,500 °C, the viscosity is approximately 25 Pa·s. As the operating temperature decreases, the slag cools and solid crystals begin to form. Since slag behaves as a non-linear fluid, we discuss the constitutive modeling of slag and the important parameters that must be studied. We propose a new constitutive model, where the stress tensor not only has a yield stress part, but it also has a viscous part with a shear rate dependency of the viscosity, along with temperature and concentration dependency, while allowing for the possibility of the normal stress effects. In Part I, we reviewed, identify and discuss the key coal ash properties and the operating conditions impacting slag behavior.

Synthesis and spectroscopic studies of biologically active tetraazamacrocyclic complexes of Mn(II, Co(II, Ni(II, Pd(II and Pt(II

Directory of Open Access Journals (Sweden)

Monika Tyagi

2014-01-01

Full Text Available Complexes of Mn(II, Co(II, Ni(II, Pd(II and Pt(II were synthesized with the macrocyclic ligand, i.e., 2,3,9,10-tetraketo-1,4,8,11-tetraazacycoletradecane. The ligand was prepared by the [2 + 2] condensation of diethyloxalate and 1,3-diamino propane and characterized by elemental analysis, mass, IR and 1H NMR spectral studies. All the complexes were characterized by elemental analysis, molar conductance, magnetic susceptibility measurements, IR, electronic and electron paramagnetic resonance spectral studies. The molar conductance measurements of Mn(II, Co(II and Ni(II complexes in DMF correspond to non electrolyte nature, whereas Pd(II and Pt(II complexes are 1:2 electrolyte. On the basis of spectral studies an octahedral geometry has been assigned for Mn(II, Co(II and Ni(II complexes, whereas square planar geometry assigned for Pd(II and Pt(II. In vitro the ligand and its metal complexes were evaluated against plant pathogenic fungi (Fusarium odum, Aspergillus niger and Rhizoctonia bataticola and some compounds found to be more active as commercially available fungicide like Chlorothalonil.

Field Portable Low Temperature Porous Layer Open Tubular Cryoadsorption Headspace Sampling and Analysis Part II: Applications*

Science.gov (United States)

Harries, Megan; Bukovsky-Reyes, Santiago; Bruno, Thomas J.

2016-01-01

This paper details the sampling methods used with the field portable porous layer open tubular cryoadsorption (PLOT-cryo) approach, described in Part I of this two-part series, applied to several analytes of interest. We conducted tests with coumarin and 2,4,6-trinitrotoluene (two solutes that were used in initial development of PLOT-cryo technology), naphthalene, aviation turbine kerosene, and diesel fuel, on a variety of matrices and test beds. We demonstrated that these analytes can be easily detected and reliably identified using the portable unit for analyte collection. By leveraging efficiency-boosting temperature control and the high flow rate multiple capillary wafer, very short collection times (as low as 3 s) yielded accurate detection. For diesel fuel spiked on glass beads, we determined a method detection limit below 1 ppm. We observed greater variability among separate samples analyzed with the portable unit than previously documented in work using the laboratory-based PLOT-cryo technology. We identify three likely sources that may help explain the additional variation: the use of a compressed air source to generate suction, matrix geometry, and variability in the local vapor concentration around the sampling probe as solute depletion occurs both locally around the probe and in the test bed as a whole. This field-portable adaptation of the PLOT-cryo approach has numerous and diverse potential applications. PMID:26726934

Field portable low temperature porous layer open tubular cryoadsorption headspace sampling and analysis part II: Applications.

Science.gov (United States)

Harries, Megan; Bukovsky-Reyes, Santiago; Bruno, Thomas J

2016-01-15

This paper details the sampling methods used with the field portable porous layer open tubular cryoadsorption (PLOT-cryo) approach, described in Part I of this two-part series, applied to several analytes of interest. We conducted tests with coumarin and 2,4,6-trinitrotoluene (two solutes that were used in initial development of PLOT-cryo technology), naphthalene, aviation turbine kerosene, and diesel fuel, on a variety of matrices and test beds. We demonstrated that these analytes can be easily detected and reliably identified using the portable unit for analyte collection. By leveraging efficiency-boosting temperature control and the high flow rate multiple capillary wafer, very short collection times (as low as 3s) yielded accurate detection. For diesel fuel spiked on glass beads, we determined a method detection limit below 1 ppm. We observed greater variability among separate samples analyzed with the portable unit than previously documented in work using the laboratory-based PLOT-cryo technology. We identify three likely sources that may help explain the additional variation: the use of a compressed air source to generate suction, matrix geometry, and variability in the local vapor concentration around the sampling probe as solute depletion occurs both locally around the probe and in the test bed as a whole. This field-portable adaptation of the PLOT-cryo approach has numerous and diverse potential applications. Published by Elsevier B.V.

Morphological caracteristics of malocclusion class II

Directory of Open Access Journals (Sweden)

Pavlović J.

2015-01-01

Full Text Available Class II malocclusion are complex anomalies of the skeletal and dental systems. The aim of this study is that the rengenkefalometrics analysis closer determine the morphological characteristics of this malocclusion. For this study were used 30 patients aged 18-30, previously clinically diagnosed class II, before the planned orthodontic treatment. The results analisis lateral cephalometric radiographs were compared with the 30 patients with class I malocclusion. Analyzed three linear and two angular cranial base dimensions and nine angular and four linear measures from the facial skeleton. The Results show: No statistically significant differensis in cranial base angle (SNBa and anterior cranial base length (S-N between class II and control Class I. Angle maxillar prognathism ( SNA is no signifikant different between class I and Class II but SNB angle were signifikant smaller. The length of maxillary base (A'-SnP is longer and the length of mandibule (Pg'-MT1/MT is signifficantly smaller. The gonial angle (ArGo-Me was smaller with open articular angle (GoArSN. Morphological characteristics of class II malocclusion are , retrognathic and smaller mandibular ligth, normognathic and longer maxilla, open articular angle with vertical tendency of the craniofacial growth pattern.

Water radiological surveillance (II)

International Nuclear Information System (INIS)

Pablo San Martin de, M.

2008-01-01

This paper summarizes the characteristics of the Environmental Surveillance Radiological Networks (ESRN) currently operating in CEDEX. In the first part, the Spanish Continental Waters ESRN has been presented. This second one describes Spanish Costal Waters ESRN and the High Sensitivity Networks in Continental and Marine Waters. It also presents the Radiological Surveillance of Drinking Waters that CEDEX carries out in waters of public consumption management by the Canal de Isabel II (CYII) and by the Mancomunity of Canals Taibilla (M.C.T.). The legislation applicable in each case is reviewed as well. Due to its extension the article has been divided into two parts. As Spanish Continental Waters ESRN has been reviewed in the first part, the others ESRN are discussed in this second one. (Author) 10 refs

Neutronics and thermohydraulics of the reactor C.E.N.E. Part II

International Nuclear Information System (INIS)

Caro, R.

1976-01-01

In this report the analysis of neutronics thermohydraulics and shielding of the 10 HWt swimming pool reactor C.E.N.E is included. In each of these chapters is given a short description of the theoretical model used, along with the theoretical versus experimental checking carried out, whenever possible, with the reactors JEN-I and JEN-II of Junta de Energia Nuclear. (Author) 11 refs

ON THE COMPACT H II GALAXY UM 408 AS SEEN BY GMOS-IFU: PHYSICAL CONDITIONS

International Nuclear Information System (INIS)

Lagos, Patricio; Telles, Eduardo; Munoz-Tunon, Casiana; Carrasco, Eleazar R.; Cuisinier, Francois; Tenorio-Tagle, Guillermo

2009-01-01

We present Integral Field Unit GMOS-IFU data of the compact H II galaxy UM 408, obtained at the Gemini South telescope, in order to derive the spatial distribution of emission lines and line ratios, kinematics, plasma parameters, and oxygen abundances as well the integrated properties over an area of 3''x4.''4 equivalent with ∼750 pc x 1100 pc located in the central part of the galaxy. The starburst in this area is resolved into two giant regions of about 1.''5 and 1'' (∼375 and ∼250 pc) diameter, respectively and separated 1.5-2'' (∼500 pc). The extinction distribution concentrate its highest values close but not coincident with the maxima of Hα emission around each one of the detected regions. This indicates that the dust has been displaced from the exciting clusters by the action of their stellar winds. The ages of these two regions, estimated using Hβ equivalent widths, suggest that they are coeval events of ∼5 Myr with stellar masses of ∼10 4 M sun . We have also used [O III]/Hβ and [S II]/Hα ratio maps to explore the excitation mechanisms in this galaxy. Comparing the data points with theoretical diagnostic models, we found that all of them are consistent with excitation by photoionization by massive stars. The Hα emission line was used to measure the radial velocity and velocity dispersion. The heliocentric radial velocity shows an apparent systemic motion where the east part of the galaxy is blueshifted, while the west part is redshifted, with a relative motion of ∼10 km s -1 . The velocity dispersion map shows supersonic values typical for extragalactic H II regions. We derived an integrated oxygen abundance of 12+log(O/H) = 7.87 summing over all spaxels in our field of view. An average value of 12+log(O/H) = 7.77 and a difference of Δ(O/H) = 0.47 between the minimum and maximum values (7.58 ± 0.06-8.05 ± 0.04) were found, considering all data points where the oxygen abundance was measured. The spatial distribution of oxygen abundance

A rare polyglycine type II-like helix motif in naturally occurring proteins.

Science.gov (United States)

Warkentin, Eberhard; Weidenweber, Sina; Schühle, Karola; Demmer, Ulrike; Heider, Johann; Ermler, Ulrich

2017-11-01

Common structural elements in proteins such as α-helices or β-sheets are characterized by uniformly repeating, energetically favorable main chain conformations which additionally exhibit a completely saturated hydrogen-bonding network of the main chain NH and CO groups. Although polyproline or polyglycine type II helices (PP II or PG II ) are frequently found in proteins, they are not considered as equivalent secondary structure elements because they do not form a similar self-contained hydrogen-bonding network of the main chain atoms. In this context our finding of an unusual motif of glycine-rich PG II -like helices in the structure of the acetophenone carboxylase core complex is of relevance. These PG II -like helices form hexagonal bundles which appear to fulfill the criterion of a (largely) saturated hydrogen-bonding network of the main-chain groups and therefore may be regarded in this sense as a new secondary structure element. It consists of a central PG II -like helix surrounded by six nearly parallel PG II -like helices in a hexagonal array, plus an additional PG II -like helix extending the array outwards. Very related structural elements have previously been found in synthetic polyglycine fibers. In both cases, all main chain NH and CO groups of the central PG II -helix are saturated by either intra- or intermolecular hydrogen-bonds, resulting in a self-contained hydrogen-bonding network. Similar, but incomplete PG II -helix patterns were also previously identified in a GTP-binding protein and an antifreeze protein. © 2017 Wiley Periodicals, Inc.

Homology modeling and docking of AahII-Nanobody complexes reveal the epitope binding site on AahII scorpion toxin.

Science.gov (United States)

Ksouri, Ayoub; Ghedira, Kais; Ben Abderrazek, Rahma; Shankar, B A Gowri; Benkahla, Alia; Bishop, Ozlem Tastan; Bouhaouala-Zahar, Balkiss

2018-02-19

Scorpion envenoming and its treatment is a public health problem in many parts of the world due to highly toxic venom polypeptides diffusing rapidly within the body of severely envenomed victims. Recently, 38 AahII-specific Nanobody sequences (Nbs) were retrieved from which the performance of NbAahII10 nanobody candidate, to neutralize the most poisonous venom compound namely AahII acting on sodium channels, was established. Herein, structural computational approach is conducted to elucidate the Nb-AahII interactions that support the biological characteristics, using Nb multiple sequence alignment (MSA) followed by modeling and molecular docking investigations (RosettaAntibody, ZDOCK software tools). Sequence and structural analysis showed two dissimilar residues of NbAahII10 CDR1 (Tyr27 and Tyr29) and an inserted polar residue Ser30 that appear to play an important role. Indeed, CDR3 region of NbAahII10 is characterized by a specific Met104 and two negatively charged residues Asp115 and Asp117. Complex dockings reveal that NbAahII17 and NbAahII38 share one common binding site on the surface of the AahII toxin divergent from the NbAahII10 one's. At least, a couple of NbAahII10 - AahII residue interactions (Gln38 - Asn44 and Arg62, His64, respectively) are mainly involved in the toxic AahII binding site. Altogether, this study gives valuable insights in the design and development of next generation of antivenom. Copyright © 2018 Elsevier Inc. All rights reserved.

DOE underground storage tank waste remediation chemical processing hazards. Part I: Technology dictionary

International Nuclear Information System (INIS)

DeMuth, S.F.

1996-10-01

This document has been prepared to aid in the development of Regulating guidelines for the Privatization of Hanford underground storage tank waste remediation. The document has been prepared it two parts to facilitate their preparation. Part II is the primary focus of this effort in that it describes the technical basis for established and potential chemical processing hazards associated with Underground Storage Tank (UST) nuclear waste remediation across the DOE complex. The established hazards involve those at Sites for which Safety Analysis Reviews (SARs) have already been prepared. Potential hazards are those involving technologies currently being developed for future applications. Part I of this document outlines the scope of Part II by briefly describing the established and potential technologies. In addition to providing the scope, Part I can be used as a technical introduction and bibliography for Regulatory personnel new to the UST waste remediation, and in particular Privatization effort. Part II of this document is not intended to provide examples of a SAR Hazards Analysis, but rather provide an intelligence gathering source for Regulatory personnel who must eventually evaluate the Privatization SAR Hazards Analysis

Pulmonary haptoglobin (pHp) is part of the surfactant system in the human lung.

Science.gov (United States)

Abdullah, Mahdi; Goldmann, Torsten

2012-11-20

Since the existence of pHp was demonstrated, it has been shown that this molecule and its receptor CD163 are regulated by different stimuli. Furthermore, a comparably fast secretion of pHp was described as well as the immuno-stimulatory effects. The intention of this study was to elucidate the role of pHp in the human lungs further. Here we show, by means of confocal microscopy and immune-electron-microscopy, a clear co-localization of pHp with surfactant protein-B in lamellar bodies of alveolar epithelial cells type II. These results are underlined by immunohistochemical stainings in differently fixed human lung tissues, which show pHp in vesicular and released form. The images of the released form resemble the intended position of surfactant in the human alveolus. pHp is secreted by Alveolar epithelial cells type II as previously shown. Moreover, pHp is co-localized with Surfactant protein-B. We conclude that the presented data shows that pHp is a native part of the surfactant system in the human lung. http://www.diagnosticpathology.diagnomx.eu/vs/2563584738239912.

COORDINATION COMPOUNDS OF NICKEL(II, COPPER(II AND COBALT(II BASED ON S-METHYLISOTHIOSEMICARBAZIDE AS DYES FOR THERMOPLASTIC POLYMERS

Directory of Open Access Journals (Sweden)

Ştefan Manole

2011-12-01

Full Text Available We have researched the color properties of coordination compounds synthesized by us previously [1] (8-(1',2'-naphthyl-1- R3-methyl-6-thiomethyl-4,5,7-triazaocta-1,3,5,7-tetraenato-1,1'-diolato(-O, O', N4, N7-M(II, where R=CH3, C6H5, M=Ni, Co, Cu, which can be used for coloring thermoplastic masses. They meet the requirements for use as a pigment for coloring thermoplastic masses.

DEPRESSION, ANXIETY AND MYOCARDIAL INFARCTION: EVERYTHING JUST BEGINS. PART II

Directory of Open Access Journals (Sweden)

Y. A. Vasyuk

2015-12-01

Full Text Available A review is devoted to a comorbidity of myocardial infarction and anxious and depressive disorders. In the first part (Rational Pharmacother. Cardiol. 2007;3:41-51 data concerning prevalence of depression in myocardial infarction, pathophysiological mechanisms connecting depression and ischemic heart disease (IHD were given. Influence of concomitant depressive disorders on clinical state and forecast of patients after myocardial infarction was discussed. The second part of the review is devoted to the anxious disorders in myocardial infarction as well as to influence of anxious and depressive disorders on life quality of patients with myocardial infarction. Besides, contemporary approaches to the therapy of anxious and depressive disorders in patients with IHD are discussed.

Belle-II Experiment Network Requirements

Energy Technology Data Exchange (ETDEWEB)

Asner, David [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Bell, Greg [ESnet; Carlson, Tim [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Cowley, David [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Dart, Eli [ESnet; Erwin, Brock [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Godang, Romulus [Univ. of South Alabama, Mobile, AL (United States); Hara, Takanori [High Energy Accelerator Research Organization (KEK), Tsukuba (Japan); Johnson, Jerry [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Johnson, Ron [Univ. of Washington, Seattle, WA (United States); Johnston, Bill [ESnet; Dam, Kerstin Kleese-van [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Kaneko, Toshiaki [High Energy Accelerator Research Organization (KEK), Tsukuba (Japan); Kubota, Yoshihiro [NII; Kuhr, Thomas [Karlsruhe Inst. of Technology (KIT) (Germany); McCoy, John [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Miyake, Hideki [High Energy Accelerator Research Organization (KEK), Tsukuba (Japan); Monga, Inder [ESnet; Nakamura, Motonori [NII; Piilonen, Leo [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States); Pordes, Ruth [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Ray, Douglas [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Russell, Richard [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Schram, Malachi [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Schroeder, Jim [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Sevior, Martin [Univ. of Melbourne (Australia); Singh, Surya [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Suzuki, Soh [High Energy Accelerator Research Organization (KEK), Tsukuba (Japan); Sasaki, Takashi [High Energy Accelerator Research Organization (KEK), Tsukuba (Japan); Williams, Jim [Indiana Univ., Bloomington, IN (United States)

2013-05-28

The Belle experiment, part of a broad-based search for new physics, is a collaboration of ~400 physicists from 55 institutions across four continents. The Belle detector is located at the KEKB accelerator in Tsukuba, Japan. The Belle detector was operated at the asymmetric electron-positron collider KEKB from 1999-2010. The detector accumulated more than 1 ab-1 of integrated luminosity, corresponding to more than 2 PB of data near 10 GeV center-of-mass energy. Recently, KEK has initiated a $400 million accelerator upgrade to be called SuperKEKB, designed to produce instantaneous and integrated luminosity two orders of magnitude greater than KEKB. The new international collaboration at SuperKEKB is called Belle II. The first data from Belle II/SuperKEKB is expected in 2015. In October 2012, senior members of the Belle-II collaboration gathered at PNNL to discuss the computing and neworking requirements of the Belle-II experiment with ESnet staff and other computing and networking experts. The day-and-a-half-long workshop characterized the instruments and facilities used in the experiment, the process of science for Belle-II, and the computing and networking equipment and configuration requirements to realize the full scientific potential of the collaboration's work.

Coordinator(a) de Servicios Clinicos. Parte I (Unidad I-IV). Parte II (Unidad V-VI). Guia. Documento de Trabajo (Clinical Services Coordinator. Part I. Units I-IV. Part II. Units V-VI. Guide. Working Document).

Science.gov (United States)

Puerto Rico State Dept. of Education, Hato Rey. Area for Vocational and Technical Education.

This guide is intended for instructing secondary students in the occupation of clinical services coordinator in a hospital. The first part contains four units on the following subjects: the occupation of clinical services coordinator; interpersonal relationships; ethical/legal aspects; and communications (telephone, intercom, and others). For each…

Evaluation report on CCTF Core-II reflood test C2-4 (Run 62)

International Nuclear Information System (INIS)

Okubo, Tsutomu; Iguchi, Tadashi; Sugimoto, Jun; Akimoto, Hajime; Murao, Yoshio; Okabe, Kazuharu.

1985-03-01

This report presents a data evaluation of the CCTF Core-II test C2-4 (Run 62), which was conducted on May 12, 1983. This test was conducted to investigate the reproducibility of tests in the CCTF Core-II test series. Therefore, the initial and boundary conditions of the present test were determined to be the same as those for the previously performed base case test (Test C2-SH1). Comparing the data of the present test with those of Test C2-SH1, the following results are obtained. (1) The initial and boundary conditions for the two tests were nearly identical except the temperature of the core barrel and the lower plenum fluid. The difference in the latter is considered to result in the difference in the core inlet subcooling of about 6 K at most. (2) The system behavior was almost identical. (3) The core cooling behavior was also nearly identical except a little difference in the rod surface temperature in the upper part of the high power region. (4) Taking account that the difference mentioned above in item (3) is small and can be explained qualitatively to be caused by the difference in the core inlet subcooling mentioned above in item (1), it is considered practically that there is the reproducibility of the thermo-hydrodynamic behavior in the CCTF Core-II tests. (author)

THE GREEN BANK TELESCOPE H II REGION DISCOVERY SURVEY. III. KINEMATIC DISTANCES

Energy Technology Data Exchange (ETDEWEB)

Anderson, L. D. [Department of Physics, West Virginia University, Morgantown, WV 26506 (United States); Bania, T. M. [Institute for Astrophysical Research, Department of Astronomy, Boston University, 725 Commonwealth Avenue, Boston, MA 02215 (United States); Balser, Dana S. [National Radio Astronomy Observatory, 520 Edgemont Road, Charlottesville, VA 22903-2475 (United States); Rood, Robert T., E-mail: Loren.Anderson@mail.wvu.edu [Astronomy Department, University of Virginia, P.O. Box 3818, Charlottesville, VA 22903-0818 (United States)

2012-07-20

Using the H I emission/absorption method, we resolve the kinematic distance ambiguity and derive distances for 149 of 182 (82%) H II regions discovered by the Green Bank Telescope H II Region Discovery Survey (GBT HRDS). The HRDS is an X-band (9 GHz, 3 cm) GBT survey of 448 previously unknown H II regions in radio recombination line and radio continuum emission. Here, we focus on HRDS sources from 67 Degree-Sign {>=} l {>=} 18 Degree-Sign , where kinematic distances are more reliable. The 25 HRDS sources in this zone that have negative recombination line velocities are unambiguously beyond the orbit of the Sun, up to 20 kpc distant. They are the most distant H II regions yet discovered. We find that 61% of HRDS sources are located at the far distance, 31% at the tangent-point distance, and only 7% at the near distance. 'Bubble' H II regions are not preferentially located at the near distance (as was assumed previously) but average 10 kpc from the Sun. The HRDS nebulae, when combined with a large sample of H II regions with previously known distances, show evidence of spiral structure in two circular arc segments of mean Galactocentric radii of 4.25 and 6.0 kpc. We perform a thorough uncertainty analysis to analyze the effect of using different rotation curves, streaming motions, and a change to the solar circular rotation speed. The median distance uncertainty for our sample of H II regions is only 0.5 kpc, or 5%. This is significantly less than the median difference between the near and far kinematic distances, 6 kpc. The basic Galactic structure results are unchanged after considering these sources of uncertainty.

Autosomal recessive type II hereditary motor and sensory neuropathy with acrodystrophy.

Science.gov (United States)

Thomas, P K; Claus, D; King, R H

1999-02-01

A family is described with presumed autosomal recessive inheritance in which three siblings developed a progressive neuropathy that combined limb weakness and severe distal sensory loss leading to prominent mutilating changes. Electrophysiological and nerve biopsy findings indicated an axonopathy. The disorder is therefore classifiable as type II hereditary motor and sensory neuropathy (HMSN II). The clinical features differ from those reported in previously described cases of autosomal recessive HMSN II. This disorder may therefore represent a new variant.

Extension of the ACE solar panels is tested in SAEF-II

Science.gov (United States)

1997-01-01

Extension of the solar panels is tested on the Advanced Composition Explorer (ACE) spacecraft in KSC's Spacecraft Assembly and Encapsulation Facility-II (SAEF-II). Scheduled for launch on a Delta II rocket from Cape Canaveral Air Station on Aug. 25, ACE will study low-energy particles of solar origin and high-energy galactic particles. The collecting power of instruments aboard ACE is 10 to 1,000 times greater than anything previously flown to collect similar data by NASA.

Management strategies to effect change in intensive care units: lessons from the world of business. Part II. Quality-improvement strategies.

Science.gov (United States)

Gershengorn, Hayley B; Kocher, Robert; Factor, Phillip

2014-03-01

The success of quality-improvement projects relies heavily on both project design and the metrics chosen to assess change. In Part II of this three-part American Thoracic Society Seminars series, we begin by describing methods for determining which data to collect, tools for data presentation, and strategies for data dissemination. As Avedis Donabedian detailed a half century ago, defining metrics in healthcare can be challenging; algorithmic determination of the best type of metric (outcome, process, or structure) can help intensive care unit (ICU) managers begin this process. Choosing appropriate graphical data displays (e.g., run charts) can prompt discussions about and promote quality improvement. Similarly, dashboards/scorecards are useful in presenting performance improvement data either publicly or privately in a visually appealing manner. To have compelling data to show, ICU managers must plan quality-improvement projects well. The second portion of this review details four quality-improvement tools-checklists, Six Sigma methodology, lean thinking, and Kaizen. Checklists have become commonplace in many ICUs to improve care quality; thinking about how to maximize their effectiveness is now of prime importance. Six Sigma methodology, lean thinking, and Kaizen are techniques that use multidisciplinary teams to organize thinking about process improvement, formalize change strategies, actualize initiatives, and measure progress. None originated within healthcare, but each has been used in the hospital environment with success. To conclude this part of the series, we demonstrate how to use these tools through an example of improving the timely administration of antibiotics to patients with sepsis.

Microcephalic osteodysplastic primordial dwarfism type II (MOPD II) with multiple vascular complications misdiagnosed as Dubowitz syndrome.

Science.gov (United States)

Dieks, Jana-Katharina; Baumer, Alessandra; Wilichowski, Ekkehard; Rauch, Anita; Sigler, Matthias

2014-09-01

To date, the genetic basis of Dubowitz syndrome (short stature, microcephaly, facial abnormalities, eczema) is unknown and vascular complications are not known to be associated with this syndrome. In microcephalic osteodysplastic primordial dwarfism type II (MOPD II; disproportionate short statue, microcephaly, facial abnormalities), however, cerebral aneurysms and other vascular abnormalities are frequent complications. MOPD II is a genetic disorder caused by mutations in the pericentrin (PCNT) gene (21q22). We report on a patient who came to our attention as a 22-year-old with subarachnoid bleeding due to a ruptured cranial aneurysm. Until then, the patient was thought and published to have Dubowitz syndrome; previously, he was treated with coronary bypass surgery for extensive coronary angiopathy. Consecutive genetic testing revealed MOPD II. After clinical stabilization, the patient was discharged to a specialized rehabilitation center where he died due to re-rupture of a cranial aneurysm. In patients with short stature-especially when clinical features are accompanied by vascular complications-MOPD II should be considered as a differential diagnosis leading to consecutive genetic testing. After detection of mutations in the PCNT gene, a full vascular status including cerebral imaging and cardiac evaluation needs to be determined in order to analyze vascular abnormalities and initiate prophylactic treatment.

Impact of a commercial glyphosate formulation on adsorption of Cd(II) and Pb(II) ions on paddy soil.

Science.gov (United States)

Divisekara, T; Navaratne, A N; Abeysekara, A S K

2018-05-01

Use of glyphosate as a weedicide on rice cultivation has been a controversial issue in Sri Lanka, due to the hypothesis that the metal complexes of commercial glyphosate is one of the causative factors of Chronic Kidney Disease of unknown aetiology (CKDu) prevalent in some parts of Sri Lanka. The effect of commercial glyphosate on the adsorption and desorption of Cd(II) and Pb(II) ions on selective paddy soil studied using batch experiments, over a wide concentration range, indicates that the Langmuir adsorption isotherm model is obeyed at low initial metal ion concentrations while the Freundlich adsorption isotherm model obeys at high metal ion concentrations in the presence and absence of glyphosate. For all cases, adsorption of both Cd(II) and Pb(II) ions obeys pseudo second order kinetics, suggesting that initial adsorption is a chemisorption process. In the presence of glyphosate formulation, the extent of adsorption of Cd(II) and Pb(II) ions on soil is decreased, while their desorption is increased at high concentrations of glyphosate. Low concentrations of glyphosate formulation do not significantly affect the desorption of metal ions from soil. Reduction of adsorption leads to enhance the concentration of Cd(II) and Pb(II) ions in the aqueous phase when in contact with soil. Copyright © 2018 Elsevier Ltd. All rights reserved.

Substitution of valine for glycine-558 in the congenital dysthrombin thrombin Quick II alters primary substrate specificity

Energy Technology Data Exchange (ETDEWEB)

Henriksen, R.A.; Mann, K.G. (Univ. of Vermont, Burlington (USA))

1989-03-07

Thrombin Quick II is one of two dysfunctional forms of thrombin derived from the previously described congenital dysprothrombin prothrombin Quick. Thrombin Quick II does not clot fibrinogen, hydrolyze p-nitroanilide substrates of thrombin, or bind N{sup 2}-(5-(dimethylamino)naphthalene-1-sulfonyl)arginine N,N-(3-ethyl-1,5-pentanediyl)amide, a high-affinity competitive inhibitor of thrombin. To determine the structural alteration in thrombin Quick II, the reduced, carboxymethylated protein was hydrolyzed by a lysyl endopeptidase. A peptide not present in a parallel thrombin hydrolysate was identified by reverse-phase chromatography. This Gly residue, which is highly conserved in the chymotrypsin family of serine proteases, forms part of the substrate binding pocket for bulky aromatic and basic side chains in chymotrypsin and trypsin, respectively. However, in porcine elastase 1, the corresponding residue is threonine. Consistent with the identified structural alteration, thrombin Quick II incorporates ({sup 3}H)diisopropyl fluorophosphate stoichiometrically and hydrolyzes the elastase substrate succinyl-Ala-Ala-Pro-Leu-p-nitroanilide with a relative k{sub cat}/K{sub M} of 0.14 when compared to thrombin. This results from a 3-fold increase in K{sub M} and a 2.5-fold decrease in k{sub cat} for thrombin Quick II when compared to thrombin acting on the same substrate. These results and those of other investigators studying mutant trypsins support the conclusion that the catalytic activity of serine proteases is very sensitive to structural alterations in the primary substrate binding pocket.

[Verrucous pastern dermatitis syndrome in heavy draught horses. Part II: Clinical findings].

Science.gov (United States)

Geburek, F; Deegen, E; Hewicker-Trautwein, M; Ohnesorge, B

2005-07-01

In the present field study the skin of the feet of 37 heavy draught horses of different breeds showing verrucous pastern dermatitis was examined clinically. Included were the degree of severity of the disease and the prevalence of anatomically normal structures associated with the skin: fetlock tufts of hair ("feathering"), ergots, chestnuts, bulges in the pastern region, cannon circumference. Each horse was examined for Chorioptes sp. skin mites. Information was also collected on the development of the skin alterations and housing conditions and feeding. These individual data were correlated with the clinical degree of severity of verrucous pastern dermatitis, which was evaluated using a numerical code (scoring system). In addition, punch biopsies were taken from the diseased skin of the feet and from healthy skin of the neck for comparative patho-histological examination (see Part III). Verrucous pastern dermatitis is a chronic disease which can be divided into four groups: scaling (group I), hyperkeratotic and hyperplastic plaque-like lesions (group II), tuberous skin masses (group III), and verrucous skin lesions with rugged surfaces (group IV). No correlation was found between the clinical degree of severity of the skin lesions and sex, breed, amount of work, use of stallions for breeding, grooming condition of the hair, white markings in the foot region, or Chorioptes sp. infestation. In regard to feeding it was found that the amount of maize and oats fed had some influence on the clinical degree of severity. Statistical analysis revealed a significant correlation between the clinical degree of severity and the age, the grooming condition of the hooves, and the mean cannon circumference. The prevalence of fetlock tufts of hair, chestnuts, ergots, and anatomically normal bulges in the pastern region also increased significantly with the clinical degree of severity. Furthermore the study revealed that the clinical degree of severity depended on the hygienic

Confirmatory Factor Analysis of the Beck Depression Inventory-II in Bariatric Surgery Candidates

Science.gov (United States)

Hall, Brian J.; Hood, Megan M.; Nackers, Lisa M.; Azarbad, Leila; Ivan, Iulia; Corsica, Joyce

2013-01-01

Screening for depression is an integral part of psychological evaluations conducted prior to bariatric surgery. The Beck Depression Inventory-II (BDI-II) is the most commonly used measure of depression in these treatment evaluations. The reliability and validity of the BDI-II has not yet been evaluated within bariatric surgery-seeking samples,…

Effect of Cu(II), Cd(II) and Zn(II) on Pb(II) biosorption by algae Gelidium-derived materials.

Science.gov (United States)

Vilar, Vítor J P; Botelho, Cidália M S; Boaventura, Rui A R

2008-06-15

Biosorption of Pb(II), Cu(II), Cd(II) and Zn(II) from binary metal solutions onto the algae Gelidium sesquipedale, an algal industrial waste and a waste-based composite material was investigated at pH 5.3, in a batch system. Binary Pb(II)/Cu(II), Pb(II)/Cd(II) and Pb(II)/Zn(II) solutions have been tested. For the same equilibrium concentrations of both metal ions (1 mmol l(-1)), approximately 66, 85 and 86% of the total uptake capacity of the biosorbents is taken by lead ions in the systems Pb(II)/Cu(II), Pb(II)/Cd(II) and Pb(II)/Zn(II), respectively. Two-metal results were fitted to a discrete and a continuous model, showing the inhibition of the primary metal biosorption by the co-cation. The model parameters suggest that Cd(II) and Zn(II) have the same decreasing effect on the Pb(II) uptake capacity. The uptake of Pb(II) was highly sensitive to the presence of Cu(II). From the discrete model it was possible to obtain the Langmuir affinity constant for Pb(II) biosorption. The presence of the co-cations decreases the apparent affinity of Pb(II). The experimental results were successfully fitted by the continuous model, at different pH values, for each biosorbent. The following sequence for the equilibrium affinity constants was found: Pb>Cu>Cd approximately Zn.

Trace element analysis provides insight into the diets of early Late Miocene ungulates from the Rudabánya II locality (Hungary)

Energy Technology Data Exchange (ETDEWEB)

Eastham, L.C.; Feranecc, R.S.; Begun, D.R.

2017-11-01

The early Late Miocene vertebrate locality of Rudabánya II (R. II) in northeastern Hungary preserves an abundance of forest-adapted ungulate species. To better understand the ecological relationships within this ancient ecosystem, we used analysis of enamel strontium/calcium (Sr/Ca) ratios to infer dietary preferences. The goals of the analysis were to: i) determine whether these ungulate species specialized in specific plants or plant parts; ii) discern whether the Sr/Ca ratios support what was previously suggested about the ecology of these species; and iii) evaluate the factors that may have acted to promote coexistence within this diverse community of predominantly browsing herbivores. Results show significant differences in the diets of the sampled species. The highest Sr/Ca ratios were displayed by the suids Parachleuastochoerus kretzoii [B1] and Propotamochoerus palaeochoerus implying a preference for Sr-rich underground plant parts. Elevated Sr/Ca ratios yielded by the cervid Lucentia aff. pierensis and equid Hippotherium intrans are indicative of intermediate feeding. The bovid Miotragocerus sp. showed higher Sr/Ca ratios than the gomphothere Tetralophodon longirostris, which is incongruent with morphological and stable isotope data, and suggested browsing by both taxa. This finding is likely the result of a difference in digestive physiology (ruminant vs. monogastric) rather than a difference in dietary behaviour. The lowest Sr/Ca ratios were displayed by the traguild Dorcatherium naui and moschid Micromeryx flourensianussuggesting a preference for Sr-poor fruits. Resource specialization and partitioning within the local environment likely acted to decrease interspecific competition and promote coexistence within the diverse ungulate community at R. II.

Trace element analysis provides insight into the diets of early Late Miocene ungulates from the Rudabánya II locality (Hungary)

International Nuclear Information System (INIS)

Eastham, L.C.; Feranecc, R.S.; Begun, D.R.

2017-01-01

The early Late Miocene vertebrate locality of Rudabánya II (R. II) in northeastern Hungary preserves an abundance of forest-adapted ungulate species. To better understand the ecological relationships within this ancient ecosystem, we used analysis of enamel strontium/calcium (Sr/Ca) ratios to infer dietary preferences. The goals of the analysis were to: i) determine whether these ungulate species specialized in specific plants or plant parts; ii) discern whether the Sr/Ca ratios support what was previously suggested about the ecology of these species; and iii) evaluate the factors that may have acted to promote coexistence within this diverse community of predominantly browsing herbivores. Results show significant differences in the diets of the sampled species. The highest Sr/Ca ratios were displayed by the suids Parachleuastochoerus kretzoii [B1] and Propotamochoerus palaeochoerus implying a preference for Sr-rich underground plant parts. Elevated Sr/Ca ratios yielded by the cervid Lucentia aff. pierensis and equid Hippotherium intrans are indicative of intermediate feeding. The bovid Miotragocerus sp. showed higher Sr/Ca ratios than the gomphothere Tetralophodon longirostris, which is incongruent with morphological and stable isotope data, and suggested browsing by both taxa. This finding is likely the result of a difference in digestive physiology (ruminant vs. monogastric) rather than a difference in dietary behaviour. The lowest Sr/Ca ratios were displayed by the traguild Dorcatherium naui and moschid Micromeryx flourensianussuggesting a preference for Sr-poor fruits. Resource specialization and partitioning within the local environment likely acted to decrease interspecific competition and promote coexistence within the diverse ungulate community at R. II.

SAGE II observations of a previously unreported stratospheric volcanic aerosol cloud in the northern polar summer of 1990

Science.gov (United States)

Yue, Glenn K.; Veiga, Robert E.; Wang, Pi-Huan

1994-01-01

Analysis of aerosol extinction profiles obtained by the spaceborne SAGE II sensor reveals that there was an anomalous increase of aerosol extinction below 18.5 km at latitudes poleward of 50 deg N from July 28 to September 9, 1990. This widespread increase of aerosol extinction in the lower stratosphere was apparently due to a remote high-latitude volcanic eruption that has not been reported to date. The increase in stratospheric optical depth in the northern polar region was about 50% in August and had diminished by October 1990. This eruption caused an increase in stratospheric aerosol mass of about 0.33 x 10(exp 5) tons, assuming the aerosol was composed of sulfuric acid and water.

Cysteine-grafted nonwoven geotextile: a new and efficient material for heavy metals sorption--Part B.

Science.gov (United States)

Vandenbossche, M; Vezin, H; Touati, N; Jimenez, M; Casetta, M; Traisnel, M

2014-10-01

The development of a new material designed to trap heavy metals from sediments or wastewater, based on a polypropylene non-woven covalently grafted with cysteine, has been reported in a previous paper (Part A). The non-woven was first functionalized with acrylic acid (AA) which is used as spacer, and then cysteine was immobilized on the substrate through covalent coupling in order to obtain the so-called PP-g-AA-cysteine. Some preliminary heavy metals adsorption tests gave interesting results: at 20 °C for 24 h and in a 1000 mg/L heavy metals solution, PP-g-AA-cysteine adsorbs 95 mg Cu/g PP (CuSO4 solution), 104 mg Cu/g PP (Cu(NO3)2 solution), 135 mg Pb/g PP (Pb(NO3)2 solution) and 21 mg Cr/g PP (Cr(NO3)3 solution). In this second part of the work, heavy metals sorption tests were carried out with Cu (II), Pb (II), and Cr (III) separately, in order to determine the sorption capacity of this new sorbent as a function of (i) the heavy metals concentration in the solution, (ii) the contact time with the solution, (iii) the pH and (iv) the ionic strength of the solution containing heavy metals. Moreover, the sorption capacity of PP-g-AA-Cysteine was studied using a polluted solution consisting of a mixture of these different heavy metals. An Electron Paramagnetic Resonance study was finally carried out in order to determine the coordination geometry in the environment of the copper trapped by the PP-g-AA-cysteine. Copyright © 2014 Elsevier Ltd. All rights reserved.

SphK1 inhibitor II (SKI-II) inhibits acute myelogenous leukemia cell growth in vitro and in vivo

International Nuclear Information System (INIS)

Yang, Li; Weng, Wei; Sun, Zhi-Xin; Fu, Xian-Jie; Ma, Jun; Zhuang, Wen-Fang

2015-01-01

Previous studies have identified sphingosine kinase 1 (SphK1) as a potential drug target for treatment of acute myeloid leukemia (AML). In the current study, we investigated the potential anti-leukemic activity of a novel and specific SphK1 inhibitor, SKI-II. We demonstrated that SKI-II inhibited growth and survival of human AML cell lines (HL-60 and U937 cells). SKI-II was more efficient than two known SphK1 inhibitors SK1-I and FTY720 in inhibiting AML cells. Meanwhile, it induced dramatic apoptosis in above AML cells, and the cytotoxicity by SKI-II was almost reversed by the general caspase inhibitor z-VAD-fmk. SKI-II treatment inhibited SphK1 activation, and concomitantly increased level of sphingosine-1-phosphate (S1P) precursor ceramide in AML cells. Conversely, exogenously-added S1P protected against SKI-II-induced cytotoxicity, while cell permeable short-chain ceramide (C6) aggravated SKI-II's lethality against AML cells. Notably, SKI-II induced potent apoptotic death in primary human AML cells, but was generally safe to the human peripheral blood mononuclear cells (PBMCs) isolated from healthy donors. In vivo, SKI-II administration suppressed growth of U937 leukemic xenograft tumors in severe combined immunodeficient (SCID) mice. These results suggest that SKI-II might be further investigated as a promising anti-AML agent. - Highlights: • SKI-II inhibits proliferation and survival of primary and transformed AML cells. • SKI-II induces apoptotic death of AML cells, but is safe to normal PBMCs. • SKI-II is more efficient than two known SphK1 inhibitors in inhibiting AML cells. • SKI-II inhibits SphK1 activity, while increasing ceramide production in AML cells. • SKI-II dose-dependently inhibits U937 xenograft growth in SCID mice

SphK1 inhibitor II (SKI-II) inhibits acute myelogenous leukemia cell growth in vitro and in vivo

Energy Technology Data Exchange (ETDEWEB)

Yang, Li; Weng, Wei; Sun, Zhi-Xin; Fu, Xian-Jie; Ma, Jun, E-mail: majuntongrensh1@126.com; Zhuang, Wen-Fang, E-mail: wenfangzhuangmd@163.com

2015-05-15

Previous studies have identified sphingosine kinase 1 (SphK1) as a potential drug target for treatment of acute myeloid leukemia (AML). In the current study, we investigated the potential anti-leukemic activity of a novel and specific SphK1 inhibitor, SKI-II. We demonstrated that SKI-II inhibited growth and survival of human AML cell lines (HL-60 and U937 cells). SKI-II was more efficient than two known SphK1 inhibitors SK1-I and FTY720 in inhibiting AML cells. Meanwhile, it induced dramatic apoptosis in above AML cells, and the cytotoxicity by SKI-II was almost reversed by the general caspase inhibitor z-VAD-fmk. SKI-II treatment inhibited SphK1 activation, and concomitantly increased level of sphingosine-1-phosphate (S1P) precursor ceramide in AML cells. Conversely, exogenously-added S1P protected against SKI-II-induced cytotoxicity, while cell permeable short-chain ceramide (C6) aggravated SKI-II's lethality against AML cells. Notably, SKI-II induced potent apoptotic death in primary human AML cells, but was generally safe to the human peripheral blood mononuclear cells (PBMCs) isolated from healthy donors. In vivo, SKI-II administration suppressed growth of U937 leukemic xenograft tumors in severe combined immunodeficient (SCID) mice. These results suggest that SKI-II might be further investigated as a promising anti-AML agent. - Highlights: • SKI-II inhibits proliferation and survival of primary and transformed AML cells. • SKI-II induces apoptotic death of AML cells, but is safe to normal PBMCs. • SKI-II is more efficient than two known SphK1 inhibitors in inhibiting AML cells. • SKI-II inhibits SphK1 activity, while increasing ceramide production in AML cells. • SKI-II dose-dependently inhibits U937 xenograft growth in SCID mice.

Tephrochronology of Bed II, Olduvai Gorge, Tanzania, and placement of the Oldowan-Acheulean transition.

Science.gov (United States)

McHenry, Lindsay J; Stanistreet, Ian G

2018-04-12

Tuffaceous marker beds, derived from volcanic products from the Ngorongoro Volcanic Highlands, help define a stratigraphic framework for the world-renowned fossil and stone tool record exposed at Olduvai Gorge, Tanzania. However, previous efforts to constrain this tuff record, especially for Olduvai Bed II, have been limited because of erosion, contamination, reworking, and the alteration of volcanic glass under saline-alkaline conditions. This paper applies previously defined geochemical and mineralogical "fingerprints" for several major Bed II marker tuffs, based on glass (where available) and phenocrysts more resistant to alteration (feldspar, hornblende, augite, and titanomagnetite), to tuffs from stratigraphic sections in the Olduvai Junction Area, including previously and recently excavated Acheulean and Oldowan sites (HWK EE (Locality (Loc) 42), EF-HR (Loc 12a), FLK (Loc 45), and MNK (Loc 88)). The Middle Bed II Bird Print Tuff (BPT) is found to be more compositionally variable than previously reported but is still valuable as a stratigraphic marker over short distances. The confirmation of blocks of Tuff IID in conglomerate helps constrain Upper Bed II stratigraphy at sites where in-situ tuffs are absent. This paper also compiles the results of published geochronological research, providing stratigraphic context and updating previously reported dates using a consistent 40 Ar/ 39 Ar reference standard age. The results of this work support the following paleoanthropologically relevant conclusions: 1) the early Acheulean site EF-HR (Loc 12a) is situated above the level of Hay's Tuff IIC, and thus sits in Upper rather than Middle Bed II, (2) the HWK EE (Loc 42) Oldowan site is constrained between Tuff IIA and Tuff IIB, just above the boundary between Lower and Middle Bed II, and 3) the Acheulean site at FLK W most likely lies within the Middle Augitic Sandstone, above Tuff IIB, similar to the placements by Leakey and Hay for the earliest Acheulean at Olduvai

Kreditní rizika z pohledu Basel II

OpenAIRE

Čabrada, Jiří

2007-01-01

The thesis "Credit risk from Basel II point of view" deals with new capital concept with main focus on the credit risk. The particular emphasis is laid on the chief issue of Basel II concept i.e. internal models. The thesis quite in detail describes the usage of basel parameters - LGD particularly - in various day-to-day business processes of credit institutions. An individual part of the thesis is devoted to credit risk mitigants and their impacts on the amount of capital requirements. The a...

Pediatric cancer gone viral. Part II: potential clinical application of oncolytic herpes simplex virus-1 in children

Directory of Open Access Journals (Sweden)

Gregory K Friedman

Full Text Available Oncolytic engineered herpes simplex viruses (HSVs possess many biologic and functional attributes that support their use in clinical trials in children with solid tumors. Tumor cells, in an effort to escape regulatory mechanisms that would impair their growth and progression, have removed many mechanisms that would have protected them from virus infection and eventual virus-mediated destruction. Viruses engineered to exploit this weakness, like mutant HSV, can be safely employed as tumor cell killers, since normal cells retain these antiviral strategies. Many preclinical studies and early phase trials in adults demonstrated that oncolytic HSV can be safely used and are highly effective in killing tumor cells that comprise pediatric malignancies, without generating the toxic side effects of nondiscriminatory chemotherapy or radiation therapy. A variety of engineered viruses have been developed and tested in numerous preclinical models of pediatric cancers and initial trials in patients are underway. In Part II of this review series, we examine the preclinical evidence to support the further advancement of oncolytic HSV in the pediatric population. We discuss clinical advances made to date in this emerging era of oncolytic virotherapy.

Physical therapy in the 21st century (Part II): evidence-based practice within the context of evidence-informed practice.

Science.gov (United States)

Dean, Elizabeth

2009-07-01

Part II of this two-part introduction to this Special Issue on physical therapy practice in the 21st century outlines a health-focused strategy for physical therapists to lead in the assault on lifestyle conditions, global health care priorities, described in Part I. Consistent with contemporary definitions of physical therapy, its practice, professional education, and research, physical therapy needs to reflect 21st-century health priorities and be aligned with global and regional public health strategies. A proposed focus on health emphasizes clinical competencies, including assessments of health, lifestyle health behaviors, and lifestyle risk factors; and the prescription of interventions to promote health and well-being in every client or patient. Such an approach is aimed to increase the threshold for chronic conditions over the life cycle and reduce their rate of progression, thereby preventing, delaying, or minimizing the severity of illness and disability. The 21st-century physical therapist needs to be able to practice such competencies within the context of a culturally diverse society to effect positive health behavior change. The physical therapist is uniquely positioned to lead in health promotion and prevention of the lifestyle conditions, address many of their causes, as well as manage these conditions. Physical therapists need to impact health globally through public and social health policy as well as one-on-one care. This role is consistent with contemporary definitions of physical therapy as the quintessential noninvasive health care practitioner, and the established efficacy and often superiority of lifestyle and lifestyle change on health outcomes compared with invasive interventions, namely, drugs and surgery. A concerted commitment by physical therapists to health and well-being and reduced health risk is consistent with minimizing the substantial social and economic burdens of lifestyle conditions globally.

Contact Modelling in Resistance Welding, Part II: Experimental Validation

DEFF Research Database (Denmark)

Song, Quanfeng; Zhang, Wenqi; Bay, Niels

2006-01-01

Contact algorithms in resistance welding presented in the previous paper are experimentally validated in the present paper. In order to verify the mechanical contact algorithm, two types of experiments, i.e. sandwich upsetting of circular, cylindrical specimens and compression tests of discs...... with a solid ring projection towards a flat ring, are carried out at room temperature. The complete algorithm, involving not only the mechanical model but also the thermal and electrical models, is validated by projection welding experiments. The experimental results are in satisfactory agreement...

The exponentiated Hencky-logarithmic strain energy. Part II: Coercivity, planar polyconvexity and existence of minimizers

Science.gov (United States)

Neff, Patrizio; Lankeit, Johannes; Ghiba, Ionel-Dumitrel; Martin, Robert; Steigmann, David

2015-08-01

We consider a family of isotropic volumetric-isochoric decoupled strain energies based on the Hencky-logarithmic (true, natural) strain tensor log U, where μ > 0 is the infinitesimal shear modulus, is the infinitesimal bulk modulus with the first Lamé constant, are dimensionless parameters, is the gradient of deformation, is the right stretch tensor and is the deviatoric part (the projection onto the traceless tensors) of the strain tensor log U. For small elastic strains, the energies reduce to first order to the classical quadratic Hencky energy which is known to be not rank-one convex. The main result in this paper is that in plane elastostatics the energies of the family are polyconvex for , extending a previous finding on its rank-one convexity. Our method uses a judicious application of Steigmann's polyconvexity criteria based on the representation of the energy in terms of the principal invariants of the stretch tensor U. These energies also satisfy suitable growth and coercivity conditions. We formulate the equilibrium equations, and we prove the existence of minimizers by the direct methods of the calculus of variations.

Inteligencia Artificial y Neurología: II Parte

Directory of Open Access Journals (Sweden)

Mario Camacho Pinto

1986-12-01

Full Text Available

Algunos comentarios sobre la primera parte me han inducido a ampliar las bases de este trabajo mediante la presentación de aspectos comunes y conceptos disímiles sobre la hipotética relación entre inteligencia artificial (lA e inteligencia humana(IH. El tema es tan complejo que un intento por resumirlo de por sí ya es atrayente además de necesario.

Microhistoria de la lA. Ciñéndome a una cruda realidad la lA nació en la Conferencia de Darmouth, año 1956, cuando John McCarthy, profesor de ciencia de computador en Stanford Un. acuñó el término de lA. Sin embargo, especulando un poco podemos decir que cierta inquietud existió desde la antigüedad, mucho antes de los computadores y aún de la electrónica (1 cuando el ser humano irresistiblemente mostraba inquietud por crear I fuera del cerebro humano. Se encuentran algunos ejemplos en la Mitología griega: Hefestos. dios del fuego y de los metales, confeccionaba creaciones semihumanas en su forja. Pigmalión desencantado de las mujeres modeló su propia ninfa en mármol y para poder casarse con ella imploró suplicante hasta conseguir que Afrodita le diera vida.

En la Europa medioeval al papa Silvestre II (apodado el hechicero por su sabiduría, año 909 D.C. se le atribuye que construía cabezas parlantes. En el siglo XVI Para celso clamó haber inventado un homúnculo. Y el rabino checo Jundo ben Loew esculpió un hombre en arcilla, José Golem, y lo constituyó espía en Praga. En 1854 el matemático británico George Boole propuso un sistema para describir lógica (2 -las leyes del pensamiento en términos matemáticos: “álgebra booliana”, “mathematical logics” que representa procesos lógicos con dos dígitos, 9 y 1.

En 1937 Alan Turing demostró que una máquina binaria podía ser programada para realizar cualquier tarea algorítmica. Esta máquina de Turing sólo podía ejecutar dos acciones: dibujar y borrar. En el mismo año Claude

System modeling and simulation at EBR-II

International Nuclear Information System (INIS)

Dean, E.M.; Lehto, W.K.; Larson, H.A.

1986-01-01

The codes being developed and verified using EBR-II data are the NATDEMO, DSNP and CSYRED. NATDEMO is a variation of the Westinghouse DEMO code coupled to the NATCON code previously used to simulate perturbations of reactor flow and inlet temperature and loss-of-flow transients leading to natural convection in EBR-II. CSYRED uses the Continuous System Modeling Program (CSMP) to simulate the EBR-II core, including power, temperature, control-rod movement reactivity effects and flow and is used primarily to model reactivity induced power transients. The Dynamic Simulator for Nuclear Power Plants (DSNP) allows a whole plant, thermal-hydraulic simulation using specific component and system models called from libraries. It has been used to simulate flow coastdown transients, reactivity insertion events and balance-of-plant perturbations

The Belle II Silicon Vertex Detector

Energy Technology Data Exchange (ETDEWEB)

Friedl, M., E-mail: markus.friedl@oeaw.ac.at [HEPHY – Institute of High Energy Physics, Nikolsdorfer Gasse 18, 1050 Vienna (Austria); Ackermann, K. [MPI Munich, Föhringer Ring 6, 80805 München (Germany); Aihara, H. [University of Tokyo, Department of Physics, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Aziz, T. [Tata Institute of Fundamental Research, Experimental High Energy Physics Group, Homi Bhabha Road, Mumbai 400 005 (India); Bergauer, T. [HEPHY – Institute of High Energy Physics, Nikolsdorfer Gasse 18, 1050 Vienna (Austria); Bozek, A. [Institute of Nuclear Physics, Division of Particle Physics and Astrophysics, ul. Radzikowskiego 152, 31 342 Krakow (Poland); Campbell, A. [DESY, Notkestrasse 85, 22607 Hamburg (Germany); Dingfelder, J. [University of Bonn, Department of Physics and Astronomy, Nussallee 12, 53115 Bonn (Germany); Drasal, Z. [Charles University, Institute of Particle and Nuclear Physics, Ke Karlovu 3, 121 16 Praha 2 (Czech Republic); Frankenberger, A. [HEPHY – Institute of High Energy Physics, Nikolsdorfer Gasse 18, 1050 Vienna (Austria); Gadow, K. [DESY, Notkestrasse 85, 22607 Hamburg (Germany); Gfall, I. [HEPHY – Institute of High Energy Physics, Nikolsdorfer Gasse 18, 1050 Vienna (Austria); Haba, J.; Hara, K.; Hara, T. [KEK, 1-1 Oho, Tsukuba, Ibaraki 305-0801 (Japan); Higuchi, T. [University of Tokyo, Kavli Institute for Physics and Mathematics of the Universe, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8583 (Japan); Himori, S. [Tohoku University, Department of Physics, Aoba Aramaki Aoba-ku, Sendai 980-8578 (Japan); Irmler, C. [HEPHY – Institute of High Energy Physics, Nikolsdorfer Gasse 18, 1050 Vienna (Austria); Ishikawa, A. [Tohoku University, Department of Physics, Aoba Aramaki Aoba-ku, Sendai 980-8578 (Japan); Joo, C. [Seoul National University, High Energy Physics Laboratory, 25-107 Shinlim-dong, Kwanak-gu, Seoul 151-742 (Korea, Republic of); and others

2013-12-21

The KEKB machine and the Belle experiment in Tsukuba (Japan) are now undergoing an upgrade, leading to an ultimate luminosity of 8×10{sup 35}cm{sup −2}s{sup −1} in order to measure rare decays in the B system with high statistics. The previous vertex detector cannot cope with this 40-fold increase of luminosity and thus needs to be replaced. Belle II will be equipped with a two-layer Pixel Detector surrounding the beam pipe, and four layers of double-sided silicon strip sensors at higher radii than the old detector. The Silicon Vertex Detector (SVD) will have a total sensitive area of 1.13m{sup 2} and 223,744 channels—twice as many as its predecessor. All silicon sensors will be made from 150 mm wafers in order to maximize their size and thus to reduce the relative contribution of the support structure. The forward part has slanted sensors of trapezoidal shape to improve the measurement precision and to minimize the amount of material as seen by particles from the vertex. Fast-shaping front-end amplifiers will be used in conjunction with an online hit time reconstruction algorithm in order to reduce the occupancy to the level of a few percent at most. A novel “Origami” chip-on-sensor scheme is used to minimize both the distance between strips and amplifier (thus reducing the electronic noise) as well as the overall material budget. This report gives an overview on the status of the Belle II SVD and its components, including sensors, front-end detector ladders, mechanics, cooling and the readout electronics.

The Belle II Silicon Vertex Detector

International Nuclear Information System (INIS)

Friedl, M.; Ackermann, K.; Aihara, H.; Aziz, T.; Bergauer, T.; Bozek, A.; Campbell, A.; Dingfelder, J.; Drasal, Z.; Frankenberger, A.; Gadow, K.; Gfall, I.; Haba, J.; Hara, K.; Hara, T.; Higuchi, T.; Himori, S.; Irmler, C.; Ishikawa, A.; Joo, C.

2013-01-01

The KEKB machine and the Belle experiment in Tsukuba (Japan) are now undergoing an upgrade, leading to an ultimate luminosity of 8×10 35 cm −2 s −1 in order to measure rare decays in the B system with high statistics. The previous vertex detector cannot cope with this 40-fold increase of luminosity and thus needs to be replaced. Belle II will be equipped with a two-layer Pixel Detector surrounding the beam pipe, and four layers of double-sided silicon strip sensors at higher radii than the old detector. The Silicon Vertex Detector (SVD) will have a total sensitive area of 1.13m 2 and 223,744 channels—twice as many as its predecessor. All silicon sensors will be made from 150 mm wafers in order to maximize their size and thus to reduce the relative contribution of the support structure. The forward part has slanted sensors of trapezoidal shape to improve the measurement precision and to minimize the amount of material as seen by particles from the vertex. Fast-shaping front-end amplifiers will be used in conjunction with an online hit time reconstruction algorithm in order to reduce the occupancy to the level of a few percent at most. A novel “Origami” chip-on-sensor scheme is used to minimize both the distance between strips and amplifier (thus reducing the electronic noise) as well as the overall material budget. This report gives an overview on the status of the Belle II SVD and its components, including sensors, front-end detector ladders, mechanics, cooling and the readout electronics

Physicochemical properties of 3,4,5-trimethoxybenzoates of Mn(II, Co(II, Ni(II and Zn(II

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W. FERENC

2005-09-01

Full Text Available The complexes of Mn(II, Co(II, Ni(II, Cu(II and Zn(II with 3,4,5-trimethoxybenzoic acid anion of the formula: M(C10H11O52·nH2O, where n = 6 for Ni(II, n = 1 for Mn(II, Co(II, Cu(II, and n = 0 for Zn, have been synthesized and characterized by elemental analysis, IR spectroscopy, X–ray diffraction measurements, thermogravimetry and magnetic studies. They are crystalline compounds characterized by various symmetry. They decompose in various ways when heated in air to 1273 K. At first, they dehydrate in one step and form anhydrous salts. The final products of decomposition are oxides of the respective metals (Mn2O3, Co3O4, NiO, CuO, ZnO. The solubilities of the analysed complexes in water at 293 K are in the orders of 10-2 – 10-4 mol dm-3. The magnetic susceptibilities of the Mn(II, Co(II, Ni(II and Cu(II complexes were measured over the range of 76–303 K and the magnetic moments were calculated. The results show that the 3,4,5-trimethoxybenzoates of Mn(II, Co(II and Ni(II are high-spin complexes but that of Cu(II forms a dimer [Cu2(C10H11O54(H2O2]. The carboxylate groups bind as monodentate or bidentate chelating or bridging ligands.

La Historia de la Contabilidad, vía privilegiada de aproximación a la investigación histórica: Cuentas de los fondos recibidos por la Factoría General de los Reinos de España para financiar la guerra de Felipe II contra el Papa Pablo IV y Enrique II de Francia (1556-1559 PARTE 1

Directory of Open Access Journals (Sweden)

Esteban Hernández Esteve

2010-12-01

Full Text Available La Historia de la Contabilidad, vía privilegiada de aproximación a la investigación histórica: Cuentas de los fondos recibidos por la Factoría General de los Reinos de España para financiar la guerra de Felipe II contra el Papa Pablo IV y Enrique II de Francia (1556-1559 PARTE 1

Os primórdios da economia social em Portugal. Contributos de Ramón de la Sagra (II Parte

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Jordi Estivill

2017-12-01

Full Text Available In continuity with the first part of the paper published in the previous issue of Sociologia: Revista da Faculdade de Letras da Universidade do Porto, the present study problematizes some clues about the emergence of the social economy in Portugal, focusing on the Revista Litteraria, published in Porto during the 19thcentury. It presents and discusses facts about Ramón de la Sagra and the influence of his work concerning the flourishing Portuguese awareness about social economy. From the collection of intense document search, it is sought to question those that are considered as the first theoretical trends regarding social economy

Plasma opening switch experiments on the Particle Beam Accelerator II

International Nuclear Information System (INIS)

Sweeney, M.A.; McDaniel, D.H.; Mendel, C.W.; Rochau, G.E.; Moore, W.B.S.; Mowrer, G.R.; Simpson, W.W.; Zagar, D.M.; Grasser, T.; McDougal, C.D.

1989-01-01

Plasma opening switch (POS) experiments have been done since 1986 on the PBFA-II ion beam accelerator to develop a rugged POS that will open rapidly ( 80%) into a high impedance (> 10 ohm) load. In a recent series of experiments on PBFA II, the authors have developed and tested three different switch designs that use magnetic fields to control and confine the injected plasma. All three configurations couple current efficiently to a 5-ohm electron beam diode. In this experimental series, the PBFA-II Delta Series, more extensive diagnostics were used than in previous switch experiments on PBFA II or on the Blackjack 5 accelerator at Maxwell Laboratories. Data from the experiments with these three switch designs is presented

PERICARDITIS: ETIOLOGY, CLASSIFICATION, CLINIC, DIAGNOSTICS, TREATMENT. PART II

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A.B. Sugak

2009-01-01

Full Text Available Pericarditis maybe caused by different agents: viruses, bacteria, tuberculosis, and it may be autoimmune. All these types of diseases have similar clinical signs, but differ by prevalence, prognosis and medical tactics. Due to achievements of radial methods of visualization, molecular biology, and immunology, we have an opportunity to provide early specific diagnostics and etiological treatment of inflammatory diseases of pericardium. The second part of lecture presents main principles of differential diagnostics of specific types of pericarditis, gives characteristics of several often accruing types of disease, and describes treatment and tactics of management of patients with pericarditis.Key words: children, pericarditis.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3:76-81

A prospective, randomised, controlled, double-blind phase I-II clinical trial on the safety of A-Part® Gel as adhesion prophylaxis after major abdominal surgery versus non-treated group

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Weis Christine

2010-07-01

Full Text Available Abstract Background Postoperative adhesions occur when fibrous strands of internal scar tissue bind anatomical structures to one another. The most common cause of intra-abdominal adhesions is previous intra-abdominal surgical intervention. Up to 74% of intestinal obstructions are caused by post surgical adhesions. Although a variety of methods and agents have been investigated to prevent post surgical adhesions, the problem of peritoneal adhesions remains largely unsolved. Materials serving as an adhesion barrier are much needed. Methods/Design This is a prospective, randomised, controlled, patient blinded and observer blinded, single centre phase I-II trial, which evaluates the safety of A-Part® Gel as an adhesion prophylaxis after major abdominal wall surgery, in comparison to an untreated control group. 60 patients undergoing an elective median laparotomy without prior abdominal surgery are randomly allocated into two groups of a 1:1- ratio. Safety parameter and primary endpoint of the study is the occurrence of wound healing impairment or peritonitis within 28 (+10 days after surgery. The frequency of anastomotic leakage within 28 days after operation, occurrence of adverse and serious adverse events during hospital stay up to 3 months and the rate of adhesions along the scar within 3 months are defined as secondary endpoints. After hospital discharge the investigator will examine the enrolled patients at 28 (+10 days and 3 months (±14 days after surgery. Discussion This trial aims to assess, whether the intra-peritoneal application of A-Part® Gel is safe and efficacious in the prevention of post-surgical adhesions after median laparotomy, in comparison to untreated controls. Trial registration NCT00646412

TRUPACT-II 157 Examination Report

International Nuclear Information System (INIS)

Barry H. O'Brien; Jeffrey M. Lacy; Kip E. Archibald

2003-01-01

This report presents the results of examination and recovery activities performed on the TRUPACT-II 157 shipping container. The container was part of a contact-handled transuranic waste shipment being transported on a truck to the Waste Isolation Pilot Plant in New Mexico when an accident occurred. Although the transport vehicle sustained only minor damage, airborne transuranic contamination was detected in air samples extracted from inside TRUPACT-II 157 at the Waste Isolation Pilot Plant. Consequently, the shipping container was rejected, resealed, and returned to the Idaho National Engineering and Environmental Laboratory where the payload was disassembled, examined, and recovered for subsequent reshipment to the Waste Isolation Pilot Plant. This report documents the results of those activities

TRUPACT-II 157 Examination Report

Energy Technology Data Exchange (ETDEWEB)

Barry H. O& #39; Brien; Jeffrey M. Lacy; Kip E. Archibald

2003-12-01

This report presents the results of examination and recovery activities performed on the TRUPACT-II 157 shipping container. The container was part of a contact-handled transuranic waste shipment being transported on a truck to the Waste Isolation Pilot Plant in New Mexico when an accident occurred. Although the transport vehicle sustained only minor damage, airborne transuranic contamination was detected in air samples extracted from inside TRUPACT-II 157 at the Waste Isolation Pilot Plant. Consequently, the shipping container was rejected, resealed, and returned to the Idaho National Engineering and Environmental Laboratory where the payload was disassembled, examined, and recovered for subsequent reshipment to the Waste Isolation Pilot Plant. This report documents the results of those activities.

Adsorption efficiencies of calcium (II ion and iron (II ion on activated carbon obtained from pericarp of rubber fruit

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Orawan Sirichote

2008-03-01

Full Text Available Determination of adsorption efficiencies of activated carbon from pericarp of rubber fruit for calcium (II ion and iron (II ion has been performed by flowing the solutions of these ions through a column of activated carbon. The weights of activated carbon in 500 mL buret column (diameter 3.2 cm for flowing calcium (II ion and iron (II ion solutions were 15 g and 10 g, respectively. The initial concentration of calcium ion was prepared to be about eight times more diluted than the true concentration found in the groundwater from the lower part of southern Thailand. Calcium (II ion concentrations were analysed by EDTA titration and its initial concentration was found to be 23.55 ppm. With a flow rate of 26 mL/min, the adsorption efficiency was 11.4 % with passed through volume 4.75 L. Iron (II ion concentrations were analysed by spectrophotometric method; its initial concentration was found to be 1.5565 ppm. At a flow rate of 22 mL/min, the adsorption efficiency was 0.42 % with passed through volume of 34.0 L.

Fragment Screening of Human Kynurenine Aminotransferase-II.

Science.gov (United States)

Jayawickrama, Gayan S; Nematollahi, Alireza; Sun, Guanchen; Church, W Bret

2018-03-01

Kynurenine aminotransferase-II (KAT-II) is a pyridoxal 5'-phosphate (PLP)-dependent enzyme that acts in the tryptophan metabolic pathway by catalyzing the transamination of kynurenine into kynurenic acid (KYNA). It is one of four isoforms in the KAT family, of which it is the primary homologue responsible for KYNA production in the mammalian brain. KAT-II is targeted for inhibition as KYNA is implicated in diseases such as schizophrenia, where it is found in elevated concentrations. Previously, many different approaches have been taken to develop KAT-II inhibitors, and herein fragment-based drug design (FBDD) approaches have been exploited to provide further lead compounds that can be designed into novel inhibitors. Surface plasmon resonance (SPR) was used to screen a fragment library containing 1000 compounds, of which 41 hits were identified. These hits were further evaluated with SPR, and 18 were selected for inhibition studies. From these hits, two fragments, F6037-0164 and F0037-7280, were pursued and determined to have an IC 50 of 524.5 (± 25.6) μM and 115.2 (± 4.5) μM, respectively. This strategy shows the viability of using FBDD in gleaning knowledge about KAT-II inhibition and generating leads for the production of KAT-II inhibitors.

Ubiquitylation and degradation of elongating RNA polymerase II

DEFF Research Database (Denmark)

Wilson, Marcus D; Harreman, Michelle; Svejstrup, Jesper Q

2013-01-01

During its journey across a gene, RNA polymerase II has to contend with a number of obstacles to its progression, including nucleosomes, DNA-binding proteins, DNA damage, and sequences that are intrinsically difficult to transcribe. Not surprisingly, a large number of elongation factors have....... In this review, we describe the mechanisms and factors responsible for the last resort mechanism of transcriptional elongation. This article is part of a Special Issue entitled: RNA polymerase II Transcript Elongation....

Analysis of Dynamic Fracture Compliance Based on Poroelastic Theory - Part II: Results of Numerical and Experimental Tests

Science.gov (United States)

Wang, Ding; Ding, Pin-bo; Ba, Jing

2018-03-01

In Part I, a dynamic fracture compliance model (DFCM) was derived based on the poroelastic theory. The normal compliance of fractures is frequency-dependent and closely associated with the connectivity of porous media. In this paper, we first compare the DFCM with previous fractured media theories in the literature in a full frequency range. Furthermore, experimental tests are performed on synthetic rock specimens, and the DFCM is compared with the experimental data in the ultrasonic frequency band. Synthetic rock specimens saturated with water have more realistic mineral compositions and pore structures relative to previous works in comparison with natural reservoir rocks. The fracture/pore geometrical and physical parameters can be controlled to replicate approximately those of natural rocks. P- and S-wave anisotropy characteristics with different fracture and pore properties are calculated and numerical results are compared with experimental data. Although the measurement frequency is relatively high, the results of DFCM are appropriate for explaining the experimental data. The characteristic frequency of fluid pressure equilibration calculated based on the specimen parameters is not substantially less than the measurement frequency. In the dynamic fracture model, the wave-induced fluid flow behavior is an important factor for the fracture-wave interaction process, which differs from the models at the high-frequency limits, for instance, Hudson's un-relaxed model.

Sears Point Tidal Marsh Restoration Project: Phase II

Science.gov (United States)

Information about the SFBWQP Sears Point Tidal Marsh Restoration Project: Phase II, part of an EPA competitive grant program to improve SF Bay water quality focused on restoring impaired waters and enhancing aquatic resources.

Synthesis and spectral studies of manganese(II), cobalt(II), nickel(II), copper(II), zinc(II), cadmium(II) and mercury(II) complexes of 4-oxo-4H-1-benzopyran-3-carboxaldehyde hydrazone derivatives

International Nuclear Information System (INIS)

Nawar, N.; Khattab, M.A.; Bekheit, M.M.; El-Kaddah, A.H.

1996-01-01

A few complexes of Mn(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and Hg(II) with 4-oxo-4H-1-benzopyran-3-(carboxaldehyde-4-chlorobenzylhydrazone) (BCBH) and 4-oxo-4H-1-benzopyran-3-(carboxaldehyde-4-methylbenzylhydrazone) (BMBH) have been synthesised and characterized by elemental analysis, molar conductivities, magnetic measurements and infrared (IR) and visible spectral studies. The IR spectra show that BCBH and BMBH behave as bidentate ligands either in the keto or enol form. (author). 24 refs., 2 tabs

Empirical Psycho-Aesthetics and Her Sisters: Substantive and Methodological Issues--Part II

Science.gov (United States)

Konecni, Vladimir J.

2013-01-01

Empirical psycho-aesthetics is approached in this two-part article from two directions. Part I, which appeared in the Winter 2012 issue of "JAE," addressed definitional and organizational issues, including the field's origins, its relation to "sister" disciplines (experimental philosophy, cognitive neuroscience of art, and neuroaesthetics), and…

[Human orgasm from the physiological perspective--part II].

Science.gov (United States)

Gałecki, Piotr; Depko, Andrzej; Jedrzejewska, Sylwia; Talarowska, Monika

2012-08-01

In contrast to the male orgasm, female orgasm is characterized by high variability and diversity, not only in the general population, but also during the life. Women experience sexual pleasure on many levels: physical, emotional, spiritual and intellectual. Sexual functioning of women and men is determined by many factors. A strong correlation between the state of subjective arousal and genital response (erection) is typical for men. In the case of women important role played: emotions, cognitive interpretation of the situation, age, self-esteem and previous sexual experiences. Among women experience orgasm during intercourse or masturbation is not a goal in itself. Modern approach to the phenomenon of orgasm and sexual education of women, make absence of orgasm as a failure. It becomes a source of low self-esteem, less self-confidence or sense of lack of attractiveness.

Synthesis, Characterization, and Biological Activity of Mn(II, Fe(II, Co(II, Ni(II, Cu(II, Zn(II, and Cd(II Complexes of N-Thiophenoyl-N′-Phenylthiocarbohydrazide

Directory of Open Access Journals (Sweden)

M. Yadav

2013-01-01

Full Text Available Mn(II, Fe(II, Co(II, Ni(II, Cu(II, Zn(II, and Cd(II complex of N-thiophenoyl -N′-phenylthiocarbohydrazide (H2 TPTH have been synthesized and characterized by elemental analysis, magnetic susceptibility measurements, infrared, NMR, electronic, and ESR spectral studies. The complexes were found to have compositions [Mn(H TPTH2], [Co(TPTH (H2O2], [Ni(TPTH (H2O2], [Cu(TPTH], [Zn(H TPTH], [Cd(H TPTH2], and [Fe(H TPTH2(EtOH]. The magnetic and electronic spectral studies suggest square planar geometry for [Cu(TPTH], tetrahedral geometry for [Zn(TPTH] and [Cd(H TPTH2], and octahedral geometry for rest of the complexes. The infrared spectral studies of the 1 : 1 deprotonated complexes suggest bonding through enolic oxygen, thiolato sulfur, and both the hydrazinic nitrogens. Thus, H2TPTH acts as a binegative tetradentate ligand. H2 TPTH and its metal complexes have been screened against several bacteria and fungi.

Redetermination of (d-penicillaminatolead(II

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Adam C. Schell

2012-04-01

Full Text Available In the title coordination polymer, [Pb(C5H9NO2S]n {systematic name: catena-poly[(μ-2-amino-3-methyl-3-sulfidobutanoatolead(II]}, the d-penicillaminate ligand coordinates to the metal ion in an N,S,O-tridentate mode. The S atom acts as a bridge to two neighbouring PbII ions, thereby forming a double thiolate chain. Moreover, the coordinating carboxylate O atom forms bridges to the PbII ions in the adjacent chain. The overall coordination sphere of the PbII ion can be described as a highly distorted pentagonal bipyramid with a void in the equatorial plane between the long Pb—S bonds probably occupied by the stereochemically active inert electron pair. The amino H atoms form N—H...S and N—H...O hydrogen bonds, resulting in a cluster of four complex units, giving rise to an R44(16 ring lying in the ab plane. The crystal structure of the title compound has been reported previously [Freeman et al. (1974. Chem. Soc. Chem. Commun. pp. 366–367] but the atomic coordinates have not been deposited in the Cambridge Structural Database (refcode DPENPB. Additional details of the hydrogen bonding are presented here.

On Railroad Tank Car Puncture Performance: Part II - Estimating Metrics

Science.gov (United States)

2016-04-12

This paper is the second in a two-part series on the puncture performance of railroad tank cars carrying hazardous materials in the event of an accident. Various metrics are often mentioned in the open literature to characterize the structural perfor...

Global limit load solutions for thick-walled cylinders with circumferential cracks under combined internal pressure, axial force and bending moment − Part II: Finite element validation

International Nuclear Information System (INIS)

Li, Yuebing; Lei, Yuebao; Gao, Zengliang

2014-01-01

Global limit load solutions for thick-walled cylinders with circumferential internal/external surface and through-wall defects under combined positive/negative axial force, positive/negative global bending moment and internal pressure have been developed in Part I of this paper. In this Part II, elastic-perfectly plastic 3-D finite element (FE) analyses are performed for selected cases, covering a wide range of geometries and load combinations, to validate the developed limit load solutions. The results show that these limit load solutions can predict the FE data very well for the cases with shallow or deep and short cracks and are conservative. For the cases with very long and deep cracks, the predictions are reasonably accurate and more conservative. -- Highlights: • Elastic-perfectly plastic 3D finite element limiting analyses of cylinders. • Thin/thick-walled cylinders with circumferential surface defects. • Combined loading for pressure, end-force and global bending moment. • Totally 1458 cases analysed and tabulated normalised results provided. • Results used to validate the developed limit load solutions in Part I of this paper

Increasing coccolith calcification during CO2 rise of the penultimate deglaciation (Termination II)

DEFF Research Database (Denmark)

Meier, K. J. S.; Berger, C.; Kinkel, Hanno

2014-01-01

during Termination II. This is partly due to an assemblage shift towards larger and heavier calcifying morphotypes, but mainly an effect of increasing coccolithophore calcification. This increase is exactly mirroring the rise in atmospheric CO2, contradicting previous findings from Termination I......Glacial to interglacial environmental changes have a strong impact on coccolithophore assemblage composition. At the same time, glacial terminations are characterised by an increase in atmospheric CO2 concentration. In order to determine how these two processes influence the calcite production...... for the coccolithophore calcification increase during atmospheric CO2 rise. Our results illustrate that even during rising atmospheric CO2 the conditions of the seawater carbonate system can be favourable for coccolithophore calcification. The total CaCO3 production of a coccolithophore assemblage under increasing CO2...

Microbunching phenomena in LCLS-II

Energy Technology Data Exchange (ETDEWEB)

Venturini, M. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Qiang, J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Papadopoulos, C. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Ding, Y. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Emma, P. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Huang, Z. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Marcus, G. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Marinelli, A. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Nosochkov, Y. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Raubenheimer, T. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Wang, L. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Woodley, M. [SLAC National Accelerator Lab., Menlo Park, CA (United States)

2015-07-14

The microbunching instability has long been recognized as a potential limiting factor to the performance of X-ray FELs. It is of particular relevance in LCLS-II due, in part, to a layout that includes a long bypass beamline between the Linac and the undulators. Here we focus on two aspects of the instability that highlight the importance of 3D effects.

Complex dynamics in diatomic molecules. Part II: Quantum trajectories

International Nuclear Information System (INIS)

Yang, C.-D.; Weng, H.-J.

2008-01-01

The second part of this paper deals with quantum trajectories in diatomic molecules, which has not been considered before in the literature. Morse potential serves as a more accurate function than a simple harmonic oscillator for illustrating a realistic picture about the vibration of diatomic molecules. However, if we determine molecular dynamics by integrating the classical force equations derived from a Morse potential, we will find that the resulting trajectories do not consist with the probabilistic prediction of quantum mechanics. On the other hand, the quantum trajectory determined by Bohmian mechanics [Bohm D. A suggested interpretation of the quantum theory in terms of hidden variable. Phys. Rev. 1952;85:166-179] leads to the conclusion that a diatomic molecule is motionless in all its vibrational eigen-states, which also contradicts probabilistic prediction of quantum mechanics. In this paper, we point out that the quantum trajectory of a diatomic molecule completely consistent with quantum mechanics does exist and can be solved from the quantum Hamilton equations of motion derived in Part I, which is based on a complex-space formulation of fractal spacetime [El Naschie MS. A review of E-Infinity theory and the mass spectrum of high energy particle physics. Chaos, Solitons and Fractals 2004;19:209-36; El Naschie MS. E-Infinity theory - some recent results and new interpretations. Chaos, Solitons and Fractals 2006;29:845-853; El Naschie MS. The concepts of E-infinity. An elementary introduction to the cantorian-fractal theory of quantum physics. Chaos, Solitons and Fractals 2004;22:495-511; El Naschie MS. SU(5) grand unification in a transfinite form. Chaos, Solitons and Fractals 2007;32:370-374; Nottale L. Fractal space-time and microphysics: towards a theory of scale relativity. Singapore: World Scientific; 1993; Ord G. Fractal space time and the statistical mechanics of random works. Chaos, Soiltons and Fractals 1996;7:821-843] approach to quantum

The structure of the local interstellar medium. VI. New Mg II, Fe II, and Mn II observations toward stars within 100 pc

International Nuclear Information System (INIS)

Malamut, Craig; Redfield, Seth; Linsky, Jeffrey L.; Wood, Brian E.; Ayres, Thomas R.

2014-01-01

We analyze high-resolution spectra obtained with the Space Telescope Imaging Spectrograph onboard the Hubble Space Telescope toward 34 nearby stars (≤100 pc) to record Mg II, Fe II, and Mn II absorption due to the local interstellar medium (LISM). Observations span the entire sky, probing previously unobserved regions of the LISM. The heavy ions studied in this survey produce narrow absorption features that facilitate the identification of multiple interstellar components. We detected one to six individual absorption components along any given sight line, and the number of absorbers roughly correlates with the pathlength. This high-resolution near-ultraviolet (NUV) spectroscopic survey was specifically designed for sight lines with existing far-UV (FUV) observations. The FUV spectra include many intrinsically broad absorption lines (i.e., of low atomic mass ions) and are often observed at medium resolution. The LISM NUV narrow-line absorption component structure presented here can be used to more accurately interpret the archival FUV observations. As an example of this synergy, we present a new analysis of the temperature and turbulence along the line of sight toward ε Ind. The new observations of LISM velocity structure are also critical in the interpretation of astrospheric absorption derived from fitting the saturated H I Lyα profile. As an example, we reanalyze the spectrum of λ And and find that this star likely does have an astrosphere. Two stars in the sample that have circumstellar disks (49 Cet and HD141569) show evidence for absorption due to disk gas. Finally, the substantially increased number of sight lines is used to test and refine the three-dimensional kinematic model of the LISM and search for previously unidentified clouds within the Local Bubble. We find that every prediction made by the Redfield and Linsky kinematic model of the LISM is confirmed by an observed component in the new lines of sight.

Anesthesia and ventilation strategies in children with asthma: part II - intraoperative management.

Science.gov (United States)

Regli, Adrian; von Ungern-Sternberg, Britta S

2014-06-01

As asthma is a frequent disease especially in children, anesthetists are increasingly providing anesthesia for children requiring elective surgery with well controlled asthma but also for those requiring urgent surgery with poorly controlled or undiagnosed asthma. This second part of this two-part review details the medical and ventilatory management throughout the perioperative period in general but also includes the perioperative management of acute bronchospasm and asthma exacerbations in children with asthma. Multiple observational trials assessing perioperative respiratory adverse events in healthy and asthmatic children provide the basis for identifying risk reduction strategies. Mainly, animal experiments and to a small extent clinical data have advanced our understanding of how anesthetic agents effect bronchial smooth muscle tone and blunt reflex bronchoconstriction. Asthma treatment outside anesthesia is well founded on a large body of evidence.Perioperative prevention strategies have increasingly been studied. However, evidence on the perioperative management, including mechanical ventilation strategies of asthmatic children, is still only fair, and further research is required. To minimize the considerable risk of perioperative respiratory adverse events in asthmatic children, perioperative management should be based on two main pillars: the preoperative optimization of asthma treatment (please refer to the first part of this two-part review) and - the focus of this second part of this review - the optimization of anesthesia management in order to optimize lung function and minimize bronchial hyperreactivity in the perioperative period.