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Sample records for osem image reconstruction

  1. Quantitative comparison of OSEM and penalized likelihood image reconstruction using relative difference penalties for clinical PET

    International Nuclear Information System (INIS)

    Ahn, Sangtae; Asma, Evren; Cheng, Lishui; Manjeshwar, Ravindra M; Ross, Steven G; Miao, Jun; Jin, Xiao; Wollenweber, Scott D

    2015-01-01

    Ordered subset expectation maximization (OSEM) is the most widely used algorithm for clinical PET image reconstruction. OSEM is usually stopped early and post-filtered to control image noise and does not necessarily achieve optimal quantitation accuracy. As an alternative to OSEM, we have recently implemented a penalized likelihood (PL) image reconstruction algorithm for clinical PET using the relative difference penalty with the aim of improving quantitation accuracy without compromising visual image quality. Preliminary clinical studies have demonstrated visual image quality including lesion conspicuity in images reconstructed by the PL algorithm is better than or at least as good as that in OSEM images. In this paper we evaluate lesion quantitation accuracy of the PL algorithm with the relative difference penalty compared to OSEM by using various data sets including phantom data acquired with an anthropomorphic torso phantom, an extended oval phantom and the NEMA image quality phantom; clinical data; and hybrid clinical data generated by adding simulated lesion data to clinical data. We focus on mean standardized uptake values and compare them for PL and OSEM using both time-of-flight (TOF) and non-TOF data. The results demonstrate improvements of PL in lesion quantitation accuracy compared to OSEM with a particular improvement in cold background regions such as lungs. (paper)

  2. Accelerated 3D-OSEM image reconstruction using a Beowulf PC cluster for pinhole SPECT

    International Nuclear Information System (INIS)

    Zeniya, Tsutomu; Watabe, Hiroshi; Sohlberg, Antti; Iida, Hidehiro

    2007-01-01

    A conventional pinhole single-photon emission computed tomography (SPECT) with a single circular orbit has limitations associated with non-uniform spatial resolution or axial blurring. Recently, we demonstrated that three-dimensional (3D) images with uniform spatial resolution and no blurring can be obtained by complete data acquired using two-circular orbit, combined with the 3D ordered subsets expectation maximization (OSEM) reconstruction method. However, a long computation time is required to obtain the reconstruction image, because of the fact that 3D-OSEM is an iterative method and two-orbit acquisition doubles the size of the projection data. To reduce the long reconstruction time, we parallelized the two-orbit pinhole 3D-OSEM reconstruction process by using a Beowulf personal computer (PC) cluster. The Beowulf PC cluster consists of seven PCs connected to Gbit Ethernet switches. Message passing interface protocol was utilized for parallelizing the reconstruction process. The projection data in a subset are distributed to each PC. The partial image forward-and back-projected in each PC is transferred to all PCs. The current image estimate on each PC is updated after summing the partial images. The performance of parallelization on the PC cluster was evaluated using two independent projection data sets acquired by a pinhole SPECT system with two different circular orbits. Parallelization using the PC cluster improved the reconstruction time with increasing number of PCs. The reconstruction time of 54 min by the single PC was decreased to 10 min when six or seven PCs were used. The speed-up factor was 5.4. The reconstruction image by the PC cluster was virtually identical with that by the single PC. Parallelization of 3D-OSEM reconstruction for pinhole SPECT using the PC cluster can significantly reduce the computation time, whereas its implementation is simple and inexpensive. (author)

  3. High resolution reconstruction of PET images using the iterative OSEM algorithm

    International Nuclear Information System (INIS)

    Doll, J.; Bublitz, O.; Werling, A.; Haberkorn, U.; Semmler, W.; Adam, L.E.; Pennsylvania Univ., Philadelphia, PA; Brix, G.

    2004-01-01

    Aim: Improvement of the spatial resolution in positron emission tomography (PET) by incorporation of the image-forming characteristics of the scanner into the process of iterative image reconstruction. Methods: All measurements were performed at the whole-body PET system ECAT EXACT HR + in 3D mode. The acquired 3D sinograms were sorted into 2D sinograms by means of the Fourier rebinning (FORE) algorithm, which allows the usage of 2D algorithms for image reconstruction. The scanner characteristics were described by a spatially variant line-spread function (LSF), which was determined from activated copper-64 line sources. This information was used to model the physical degradation processes in PET measurements during the course of 2D image reconstruction with the iterative OSEM algorithm. To assess the performance of the high-resolution OSEM algorithm, phantom measurements performed at a cylinder phantom, the hotspot Jaszczack phantom, and the 3D Hoffmann brain phantom as well as different patient examinations were analyzed. Results: Scanner characteristics could be described by a Gaussian-shaped LSF with a full-width at half-maximum increasing from 4.8 mm at the center to 5.5 mm at a radial distance of 10.5 cm. Incorporation of the LSF into the iteration formula resulted in a markedly improved resolution of 3.0 and 3.5 mm, respectively. The evaluation of phantom and patient studies showed that the high-resolution OSEM algorithm not only lead to a better contrast resolution in the reconstructed activity distributions but also to an improved accuracy in the quantification of activity concentrations in small structures without leading to an amplification of image noise or even the occurrence of image artifacts. Conclusion: The spatial and contrast resolution of PET scans can markedly be improved by the presented image restauration algorithm, which is of special interest for the examination of both patients with brain disorders and small animals. (orig.)

  4. Partial volume correction in SPECT reconstruction with OSEM

    Energy Technology Data Exchange (ETDEWEB)

    Erlandsson, Kjell, E-mail: k.erlandsson@ucl.ac.uk [Institute of Nuclear Medicine, University College London and University College London Hospital, London NW1 2BU (United Kingdom); Thomas, Ben; Dickson, John; Hutton, Brian F. [Institute of Nuclear Medicine, University College London and University College London Hospital, London NW1 2BU (United Kingdom)

    2011-08-21

    SPECT images suffer from poor spatial resolution, which leads to partial volume effects due to cross-talk between different anatomical regions. By utilising high-resolution structural images (CT or MRI) it is possible to compensate for these effects. Traditional partial volume correction (PVC) methods suffer from various limitations, such as correcting a single region only, returning only regional mean values, or assuming a stationary point spread function (PSF). We recently presented a novel method in which PVC was combined with the reconstruction process in order to take into account the distance dependent PSF in SPECT, which was based on filtered backprojection (FBP) reconstruction. We now present a new method based on the iterative OSEM algorithm, which has advantageous noise properties compared to FBP. We have applied this method to a series of 10 brain SPECT studies performed on healthy volunteers using the DATSCAN tracer. T1-weighted MRI images were co-registered to the SPECT data and segmented into 33 anatomical regions. The SPECT data were reconstructed using OSEM, and PVC was applied in the projection domain at each iteration. The correction factors were calculated by forward projection of a piece-wise constant image, generated from the segmented MRI. Images were also reconstructed using FBP and standard OSEM with and without resolution recovery (RR) for comparison. The images were evaluated in terms of striatal contrast and regional variability (CoV). The mean striatal contrast obtained with OSEM, OSEM-RR and OSEM-PVC relative to FBP were 1.04, 1.42 and 1.53, respectively, and the mean striatal CoV values are 1.05, 1.53, 1.07. Both OSEM-RR and OSEM-PVC results in images with significantly higher contrast as compared to FBP or OSEM, but OSEM-PVC avoids the increased regional variability of OSEM-RR due to improved structural definition.

  5. Accurate 3D reconstruction by a new PDS-OSEM algorithm for HRRT

    International Nuclear Information System (INIS)

    Chen, Tai-Been; Horng-Shing Lu, Henry; Kim, Hang-Keun; Son, Young-Don; Cho, Zang- Hee

    2014-01-01

    State-of-the-art high resolution research tomography (HRRT) provides high resolution PET images with full 3D human brain scanning. But, a short time frame in dynamic study causes many problems related to the low counts in the acquired data. The PDS-OSEM algorithm was proposed to reconstruct the HRRT image with a high signal-to-noise ratio that provides accurate information for dynamic data. The new algorithm was evaluated by simulated image, empirical phantoms, and real human brain data. Meanwhile, the time activity curve was adopted to validate a reconstructed performance of dynamic data between PDS-OSEM and OP-OSEM algorithms. According to simulated and empirical studies, the PDS-OSEM algorithm reconstructs images with higher quality, higher accuracy, less noise, and less average sum of square error than those of OP-OSEM. The presented algorithm is useful to provide quality images under the condition of low count rates in dynamic studies with a short scan time. - Highlights: • The PDS-OSEM reconstructs PET images with iteratively compensating random and scatter corrections from prompt sinogram. • The PDS-OSEM can reconstruct PET images with low count data and data contaminations. • The PDS-OSEM provides less noise and higher quality of reconstructed images than those of OP-OSEM algorithm in statistical sense

  6. Incorporating HYPR de-noising within iterative PET reconstruction (HYPR-OSEM)

    Science.gov (United States)

    (Kevin Cheng, Ju-Chieh; Matthews, Julian; Sossi, Vesna; Anton-Rodriguez, Jose; Salomon, André; Boellaard, Ronald

    2017-08-01

    HighlY constrained back-PRojection (HYPR) is a post-processing de-noising technique originally developed for time-resolved magnetic resonance imaging. It has been recently applied to dynamic imaging for positron emission tomography and shown promising results. In this work, we have developed an iterative reconstruction algorithm (HYPR-OSEM) which improves the signal-to-noise ratio (SNR) in static imaging (i.e. single frame reconstruction) by incorporating HYPR de-noising directly within the ordered subsets expectation maximization (OSEM) algorithm. The proposed HYPR operator in this work operates on the target image(s) from each subset of OSEM and uses the sum of the preceding subset images as the composite which is updated every iteration. Three strategies were used to apply the HYPR operator in OSEM: (i) within the image space modeling component of the system matrix in forward-projection only, (ii) within the image space modeling component in both forward-projection and back-projection, and (iii) on the image estimate after the OSEM update for each subset thus generating three forms: (i) HYPR-F-OSEM, (ii) HYPR-FB-OSEM, and (iii) HYPR-AU-OSEM. Resolution and contrast phantom simulations with various sizes of hot and cold regions as well as experimental phantom and patient data were used to evaluate the performance of the three forms of HYPR-OSEM, and the results were compared to OSEM with and without a post reconstruction filter. It was observed that the convergence in contrast recovery coefficients (CRC) obtained from all forms of HYPR-OSEM was slower than that obtained from OSEM. Nevertheless, HYPR-OSEM improved SNR without degrading accuracy in terms of resolution and contrast. It achieved better accuracy in CRC at equivalent noise level and better precision than OSEM and better accuracy than filtered OSEM in general. In addition, HYPR-AU-OSEM has been determined to be the more effective form of HYPR-OSEM in terms of accuracy and precision based on the studies

  7. Influence of the partial volume correction method on (18)F-fluorodeoxyglucose brain kinetic modelling from dynamic PET images reconstructed with resolution model based OSEM.

    Science.gov (United States)

    Bowen, Spencer L; Byars, Larry G; Michel, Christian J; Chonde, Daniel B; Catana, Ciprian

    2013-10-21

    Kinetic parameters estimated from dynamic (18)F-fluorodeoxyglucose ((18)F-FDG) PET acquisitions have been used frequently to assess brain function in humans. Neglecting partial volume correction (PVC) for a dynamic series has been shown to produce significant bias in model estimates. Accurate PVC requires a space-variant model describing the reconstructed image spatial point spread function (PSF) that accounts for resolution limitations, including non-uniformities across the field of view due to the parallax effect. For ordered subsets expectation maximization (OSEM), image resolution convergence is local and influenced significantly by the number of iterations, the count density, and background-to-target ratio. As both count density and background-to-target values for a brain structure can change during a dynamic scan, the local image resolution may also concurrently vary. When PVC is applied post-reconstruction the kinetic parameter estimates may be biased when neglecting the frame-dependent resolution. We explored the influence of the PVC method and implementation on kinetic parameters estimated by fitting (18)F-FDG dynamic data acquired on a dedicated brain PET scanner and reconstructed with and without PSF modelling in the OSEM algorithm. The performance of several PVC algorithms was quantified with a phantom experiment, an anthropomorphic Monte Carlo simulation, and a patient scan. Using the last frame reconstructed image only for regional spread function (RSF) generation, as opposed to computing RSFs for each frame independently, and applying perturbation geometric transfer matrix PVC with PSF based OSEM produced the lowest magnitude bias kinetic parameter estimates in most instances, although at the cost of increased noise compared to the PVC methods utilizing conventional OSEM. Use of the last frame RSFs for PVC with no PSF modelling in the OSEM algorithm produced the lowest bias in cerebral metabolic rate of glucose estimates, although by less than 5% in

  8. Enhanced 3D PET OSEM reconstruction using inter-update Metz filtering

    International Nuclear Information System (INIS)

    Jacobson, M.; Levkovitz, R.; Ben-Tal, A.; Thielemans, K.; Spinks, T.; Belluzzo, D.; Pagani, E.; Bettinardi, V.; Gilardi, M.C.; Zverovich, A.; Mitra, G.

    2000-01-01

    We present an enhancement of the OSEM (ordered set expectation maximization) algorithm for 3D PET reconstruction, which we call the inter-update Metz filtered OSEM (IMF-OSEM). The IMF-OSEM algorithm incorporates filtering action into the image updating process in order to improve the quality of the reconstruction. With this technique, the multiplicative correction image - ordinarily used to update image estimates in plain OSEM - is applied to a Metz-filtered version of the image estimate at certain intervals. In addition, we present a software implementation that employs several high-speed features to accelerate reconstruction. These features include, firstly, forward and back projection functions which make full use of symmetry as well as a fast incremental computation technique. Secondly, the software has the capability of running in parallel mode on several processors. The parallelization approach employed yields a significant speed-up, which is nearly independent of the amount of data. Together, these features lead to reasonable reconstruction times even when using large image arrays and non-axially compressed projection data. The performance of IMF-OSEM was tested on phantom data acquired on the GE Advance scanner. Our results demonstrate that an appropriate choice of Metz filter parameters can improve the contrast-noise balance of certain regions of interest relative to both plain and post-filtered OSEM, and to the GE commercial reprojection algorithm software. (author)

  9. Characterization and simulation of noise in PET images reconstructed with OSEM: Development of a method for the generation of synthetic images.

    Science.gov (United States)

    Castro, P; Huerga, C; Chamorro, P; Garayoa, J; Roch, M; Pérez, L

    2018-04-17

    The goals of the study are to characterize imaging properties in 2D PET images reconstructed with the iterative algorithm ordered-subset expectation maximization (OSEM) and to propose a new method for the generation of synthetic images. The noise is analyzed in terms of its magnitude, spatial correlation, and spectral distribution through standard deviation, autocorrelation function, and noise power spectrum (NPS), respectively. Their variations with position and activity level are also analyzed. This noise analysis is based on phantom images acquired from 18 F uniform distributions. Experimental recovery coefficients of hot spheres in different backgrounds are employed to study the spatial resolution of the system through point spread function (PSF). The NPS and PSF functions provide the baseline for the proposed simulation method: convolution with PSF as kernel and noise addition from NPS. The noise spectral analysis shows that the main contribution is of random nature. It is also proven that attenuation correction does not alter noise texture but it modifies its magnitude. Finally, synthetic images of 2 phantoms, one of them an anatomical brain, are quantitatively compared with experimental images showing a good agreement in terms of pixel values and pixel correlations. Thus, the contrast to noise ratio for the biggest sphere in the NEMA IEC phantom is 10.7 for the synthetic image and 8.8 for the experimental image. The properties of the analyzed OSEM-PET images can be described by NPS and PSF functions. Synthetic images, even anatomical ones, are successfully generated by the proposed method based on the NPS and PSF. Copyright © 2018 Sociedad Española de Medicina Nuclear e Imagen Molecular. Publicado por Elsevier España, S.L.U. All rights reserved.

  10. Accurate 3D reconstruction by a new PDS-OSEM algorithm for HRRT

    Science.gov (United States)

    Chen, Tai-Been; Horng-Shing Lu, Henry; Kim, Hang-Keun; Son, Young-Don; Cho, Zang-Hee

    2014-03-01

    State-of-the-art high resolution research tomography (HRRT) provides high resolution PET images with full 3D human brain scanning. But, a short time frame in dynamic study causes many problems related to the low counts in the acquired data. The PDS-OSEM algorithm was proposed to reconstruct the HRRT image with a high signal-to-noise ratio that provides accurate information for dynamic data. The new algorithm was evaluated by simulated image, empirical phantoms, and real human brain data. Meanwhile, the time activity curve was adopted to validate a reconstructed performance of dynamic data between PDS-OSEM and OP-OSEM algorithms. According to simulated and empirical studies, the PDS-OSEM algorithm reconstructs images with higher quality, higher accuracy, less noise, and less average sum of square error than those of OP-OSEM. The presented algorithm is useful to provide quality images under the condition of low count rates in dynamic studies with a short scan time.

  11. Image-based point spread function implementation in a fully 3D OSEM reconstruction algorithm for PET.

    Science.gov (United States)

    Rapisarda, E; Bettinardi, V; Thielemans, K; Gilardi, M C

    2010-07-21

    The interest in positron emission tomography (PET) and particularly in hybrid integrated PET/CT systems has significantly increased in the last few years due to the improved quality of the obtained images. Nevertheless, one of the most important limits of the PET imaging technique is still its poor spatial resolution due to several physical factors originating both at the emission (e.g. positron range, photon non-collinearity) and at detection levels (e.g. scatter inside the scintillating crystals, finite dimensions of the crystals and depth of interaction). To improve the spatial resolution of the images, a possible way consists of measuring the point spread function (PSF) of the system and then accounting for it inside the reconstruction algorithm. In this work, the system response of the GE Discovery STE operating in 3D mode has been characterized by acquiring (22)Na point sources in different positions of the scanner field of view. An image-based model of the PSF was then obtained by fitting asymmetric two-dimensional Gaussians on the (22)Na images reconstructed with small pixel sizes. The PSF was then incorporated, at the image level, in a three-dimensional ordered subset maximum likelihood expectation maximization (OS-MLEM) reconstruction algorithm. A qualitative and quantitative validation of the algorithm accounting for the PSF has been performed on phantom and clinical data, showing improved spatial resolution, higher contrast and lower noise compared with the corresponding images obtained using the standard OS-MLEM algorithm.

  12. Similarity-regulation of OS-EM for accelerated SPECT reconstruction

    Science.gov (United States)

    Vaissier, P. E. B.; Beekman, F. J.; Goorden, M. C.

    2016-06-01

    Ordered subsets expectation maximization (OS-EM) is widely used to accelerate image reconstruction in single photon emission computed tomography (SPECT). Speedup of OS-EM over maximum likelihood expectation maximization (ML-EM) is close to the number of subsets used. Although a high number of subsets can shorten reconstruction times significantly, it can also cause severe image artifacts such as improper erasure of reconstructed activity if projections contain few counts. We recently showed that such artifacts can be prevented by using a count-regulated OS-EM (CR-OS-EM) algorithm which automatically adapts the number of subsets for each voxel based on the estimated number of counts that the voxel contributed to the projections. While CR-OS-EM reached high speed-up over ML-EM in high-activity regions of images, speed in low-activity regions could still be very slow. In this work we propose similarity-regulated OS-EM (SR-OS-EM) as a much faster alternative to CR-OS-EM. SR-OS-EM also automatically and locally adapts the number of subsets, but it uses a different criterion for subset regulation: the number of subsets that is used for updating an individual voxel depends on how similar the reconstruction algorithm would update the estimated activity in that voxel with different subsets. Reconstructions of an image quality phantom and in vivo scans show that SR-OS-EM retains all of the favorable properties of CR-OS-EM, while reconstruction speed can be up to an order of magnitude higher in low-activity regions. Moreover our results suggest that SR-OS-EM can be operated with identical reconstruction parameters (including the number of iterations) for a wide range of count levels, which can be an additional advantage from a user perspective since users would only have to post-filter an image to present it at an appropriate noise level.

  13. Evaluation of bias and variance in low-count OSEM list mode reconstruction

    International Nuclear Information System (INIS)

    Jian, Y; Carson, R E; Planeta, B

    2015-01-01

    Statistical algorithms have been widely used in PET image reconstruction. The maximum likelihood expectation maximization reconstruction has been shown to produce bias in applications where images are reconstructed from a relatively small number of counts. In this study, image bias and variability in low-count OSEM reconstruction are investigated on images reconstructed with MOLAR (motion-compensation OSEM list-mode algorithm for resolution-recovery reconstruction) platform. A human brain ([ 11 C]AFM) and a NEMA phantom are used in the simulation and real experiments respectively, for the HRRT and Biograph mCT. Image reconstructions were repeated with different combinations of subsets and iterations. Regions of interest were defined on low-activity and high-activity regions to evaluate the bias and noise at matched effective iteration numbers (iterations × subsets). Minimal negative biases and no positive biases were found at moderate count levels and less than 5% negative bias was found using extremely low levels of counts (0.2 M NEC). At any given count level, other factors, such as subset numbers and frame-based scatter correction may introduce small biases (1–5%) in the reconstructed images. The observed bias was substantially lower than that reported in the literature, perhaps due to the use of point spread function and/or other implementation methods in MOLAR. (paper)

  14. Studies oriented to optimize the image quality of the small animal PET: Clear PET, modifying some of the parameters of the reconstruction algorithm IMF-OSEM 3D on the data acquisition simulated with GAMOS

    International Nuclear Information System (INIS)

    Canadas, M.; Mendoza, J.; Embid, M.

    2007-01-01

    This report presents studies oriented to optimize the image quality of the small animal PET: Clear- PET. Certain figures of merit (FOM) were used to assess a quantitative value of the contrast and delectability of lesions. The optimization was carried out modifying some of the parameters in the reconstruction software of the scanner, imaging a mini-Derenzo phantom and a cylinder phantom with background activity and two hot spheres. Specifically, it was evaluated the incidence of the inter-update Metz filter (IMF) inside the iterative reconstruction algorithm 3D OSEM. The data acquisition was simulated using the GAMOS framework (Monte Carlo simulation). Integrating GAMOS output with the reconstruction software of the scanner was an additional novelty of this work, to achieve this, data sets were written with the list-mode format (LMF) of ClearPET. In order to verify the optimum values obtained, we foresee to make real acquisitions in the ClearPET of CIEMAT. (Author) 17 refs

  15. LOR-OSEM: statistical PET reconstruction from raw line-of-response histograms

    International Nuclear Information System (INIS)

    Kadrmas, Dan J

    2004-01-01

    Iterative statistical reconstruction methods are becoming the standard in positron emission tomography (PET). Conventional maximum-likelihood expectation-maximization (MLEM) and ordered-subsets (OSEM) algorithms act on data which have been pre-processed into corrected, evenly-spaced histograms; however, such pre-processing corrupts the Poisson statistics. Recent advances have incorporated attenuation, scatter and randoms compensation into the iterative reconstruction. The objective of this work was to incorporate the remaining pre-processing steps, including arc correction, to reconstruct directly from raw unevenly-spaced line-of-response (LOR) histograms. This exactly preserves Poisson statistics and full spatial information in a manner closely related to listmode ML, making full use of the ML statistical model. The LOR-OSEM algorithm was implemented using a rotation-based projector which maps directly to the unevenly-spaced LOR grid. Simulation and phantom experiments were performed to characterize resolution, contrast and noise properties for 2D PET. LOR-OSEM provided a beneficial noise-resolution tradeoff, outperforming AW-OSEM by about the same margin that AW-OSEM outperformed pre-corrected OSEM. The relationship between LOR-ML and listmode ML algorithms was explored, and implementation differences are discussed. LOR-OSEM is a viable alternative to AW-OSEM for histogram-based reconstruction with improved spatial resolution and noise properties

  16. Correction of head motion artifacts in SPECT with fully 3-D OS-EM reconstruction

    International Nuclear Information System (INIS)

    Fulton, R.R.

    1998-01-01

    Full text: A method which relies on continuous monitoring of head position has been developed to correct for head motion in SPECT studies of the brain. Head position and orientation are monitored during data acquisition by an inexpensive head tracking system (ADL-1, Shooting Star Technology, Rosedale, British Colombia). Motion correction involves changing the projection geometry to compensate for motion (using data from the head tracker), and reconstructing with a fully 3-D OS-EM algorithm. The reconstruction algorithm can accommodate any number of movements and any projection geometry. A single iteration of 3-D OS-EM using all available projections provides a satisfactory 3-D reconstruction, essentially free of motion artifacts. The method has been validated in studies of the 3-D Hoffman brain phantom. Multiple 36- degree acquisitions, each with the phantom in a different position, were performed on a Trionix triple head camera. Movements were simulated by combining projections from the different acquisitions. Accuracy was assessed by comparison with a motion-free reconstruction, visually and by calculating mean squared error (MSE). Motion correction reduced distortion perceptibly and, depending on the motions applied, improved MSE by up to an order of magnitude. Three-dimensional reconstruction of the 128 x 128 x 128 data set took 2- minutes on a SUN Ultra 1 workstation. This motion correction technique can be retro-fitted to existing SPECT systems and could be incorporated in future SPECT camera designs. It appears to be applicable in PET as well as SPECT, to be able to correct for any head movements, and to have the potential to improve the accuracy of tomographic brain studies under clinical imaging conditions

  17. Studies oriented to optimize the image quality of the small animal PET: Clear PET, modifying some of the parameters of the reconstruction algorithm IMF-OSEM 3D on the data acquisition simulated with GAMOS; Estudios para la optimizaciOn de la calidad de imagen en el escaner ClearPET, modifi cando parametros del algoritmo IMF-OSEM 3D sobre adquisiciones simuladas con GAMOS

    Energy Technology Data Exchange (ETDEWEB)

    Canadas, M.; Mendoza, J.; Embid, M.

    2007-09-27

    This report presents studies oriented to optimize the image quality of the small animal PET: Clear- PET. Certain figures of merit (FOM) were used to assess a quantitative value of the contrast and delectability of lesions. The optimization was carried out modifying some of the parameters in the reconstruction software of the scanner, imaging a mini-Derenzo phantom and a cylinder phantom with background activity and two hot spheres. Specifically, it was evaluated the incidence of the inter-update Metz filter (IMF) inside the iterative reconstruction algorithm 3D OSEM. The data acquisition was simulated using the GAMOS framework (Monte Carlo simulation). Integrating GAMOS output with the reconstruction software of the scanner was an additional novelty of this work, to achieve this, data sets were written with the list-mode format (LMF) of ClearPET. In order to verify the optimum values obtained, we foresee to make real acquisitions in the ClearPET of CIEMAT. (Author) 17 refs.

  18. HeinzelCluster: accelerated reconstruction for FORE and OSEM3D.

    Science.gov (United States)

    Vollmar, S; Michel, C; Treffert, J T; Newport, D F; Casey, M; Knöss, C; Wienhard, K; Liu, X; Defrise, M; Heiss, W D

    2002-08-07

    Using iterative three-dimensional (3D) reconstruction techniques for reconstruction of positron emission tomography (PET) is not feasible on most single-processor machines due to the excessive computing time needed, especially so for the large sinogram sizes of our high-resolution research tomograph (HRRT). In our first approach to speed up reconstruction time we transform the 3D scan into the format of a two-dimensional (2D) scan with sinograms that can be reconstructed independently using Fourier rebinning (FORE) and a fast 2D reconstruction method. On our dedicated reconstruction cluster (seven four-processor systems, Intel PIII@700 MHz, switched fast ethernet and Myrinet, Windows NT Server), we process these 2D sinograms in parallel. We have achieved a speedup > 23 using 26 processors and also compared results for different communication methods (RPC, Syngo, Myrinet GM). The other approach is to parallelize OSEM3D (implementation of C Michel), which has produced the best results for HRRT data so far and is more suitable for an adequate treatment of the sinogram gaps that result from the detector geometry of the HRRT. We have implemented two levels of parallelization for four dedicated cluster (a shared memory fine-grain level on each node utilizing all four processors and a coarse-grain level allowing for 15 nodes) reducing the time for one core iteration from over 7 h to about 35 min.

  19. Optimizing the number of equivalent iterations of 3D OSEM in SPECT reconstruction of I-131 focal activities

    International Nuclear Information System (INIS)

    Koral, Kenneth F.; Kritzmaan, James N.; Rogers, Virginia E.; Ackermann, Robert J.; A Fessler, Jeffrey

    2007-01-01

    To externally estimate the radiation dose to a tumor during therapy with I-131 radiopharmaceuticals, and its distribution, one must accurately estimate activity, and its distribution, by means of SPECT imaging. Our objective is to characterize the quantification of the total activity in focal targets and in their uniform background, and of the activity distribution within the targets, after 3D Ordered Subsets Expectation Maximization (OSEM) reconstruction with attenuation and scatter correction and no post smoothing, in the good-counting-statistics case. A cylindrical phantom containing seven spheres simulating tumors, ranging in volume from 209 to 4.2 cm 3 , and filled with an I-131 water solution containing background, was imaged. A Siemens Symbia SPECT/CT scanner was used to acquire 128x128 projection images, employing 60 angles over 360 o . With dynamic SPECT, 10 sequential acquisitions of 15 min duration each were obtained and each was reconstructed with particular values of the number of subsets and the number of iterations. Let the product of the number of subsets times the number of iterations equal the equivalent number of iterations, EI. The counts-to-activity conversion factor was derived from the average ratio of total count divided by true activity for the largest sphere at the largest value of EI. Then, for the activity of each sphere at each of the values of EI, we evaluated (1) the fractional variance (variance in estimate over true activity), (2) the fractional bias (average estimate bias over true activity) and (3) the fractional error (the root mean square error (RMSE) in the estimate divided by the true activity). The fractional bias and fractional variance were smaller for the larger spheres compared to the smaller (the fractional bias decreased faster with an increase in the fractional variance for them as well). The RMSE was dominated by the bias. The fractional error decreased as EI increased for all sphere sizes. The minimum average value

  20. Spatial resolution of the HRRT PET scanner using 3D-OSEM PSF reconstruction

    DEFF Research Database (Denmark)

    Olesen, Oline Vinter; Sibomana, Merence; Keller, Sune Høgild

    2009-01-01

    The spatial resolution of the Siemens High Resolution Research Tomograph (HRRT) dedicated brain PET scanner installed at Copenhagen University Hospital (Rigshospitalet) was measured using a point-source phantom with high statistics. Further, it was demonstrated how the newly developed 3D-OSEM PSF...

  1. Advancement in PET quantification using 3D-OP-OSEM point spread function reconstruction with the HRRT

    Energy Technology Data Exchange (ETDEWEB)

    Varrone, Andrea; Sjoeholm, Nils; Gulyas, Balazs; Halldin, Christer; Farde, Lars [Karolinska Hospital, Karolinska Institutet, Department of Clinical Neuroscience, Psychiatry Section and Stockholm Brain Institute, Stockholm (Sweden); Eriksson, Lars [Karolinska Hospital, Karolinska Institutet, Department of Clinical Neuroscience, Psychiatry Section and Stockholm Brain Institute, Stockholm (Sweden); Siemens Molecular Imaging, Knoxville, TN (United States); University of Stockholm, Department of Physics, Stockholm (Sweden)

    2009-10-15

    Image reconstruction including the modelling of the point spread function (PSF) is an approach improving the resolution of the PET images. This study assessed the quantitative improvements provided by the implementation of the PSF modelling in the reconstruction of the PET data using the High Resolution Research Tomograph (HRRT). Measurements were performed on the NEMA-IEC/2001 (Image Quality) phantom for image quality and on an anthropomorphic brain phantom (STEPBRAIN). PSF reconstruction was also applied to PET measurements in two cynomolgus monkeys examined with [{sup 18}F]FE-PE2I (dopamine transporter) and with [{sup 11}C]MNPA (D{sub 2} receptor), and in one human subject examined with [{sup 11}C]raclopride (D{sub 2} receptor). PSF reconstruction increased the recovery coefficient (RC) in the NEMA phantom by 11-40% and the grey to white matter ratio in the STEPBRAIN phantom by 17%. PSF reconstruction increased binding potential (BP{sub ND}) in the striatum and midbrain by 14 and 18% in the [{sup 18}F]FE-PE2I study, and striatal BP{sub ND} by 6 and 10% in the [{sup 11}C]MNPA and [{sup 11}C]raclopride studies. PSF reconstruction improved quantification by increasing the RC and thus reducing the partial volume effect. This method provides improved conditions for PET quantification in clinical studies with the HRRT system, particularly when targeting receptor populations in small brain structures. (orig.)

  2. Impact of PET/CT image reconstruction methods and liver uptake normalization strategies on quantitative image analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kuhnert, Georg; Sterzer, Sergej; Kahraman, Deniz; Dietlein, Markus; Drzezga, Alexander; Kobe, Carsten [University Hospital of Cologne, Department of Nuclear Medicine, Cologne (Germany); Boellaard, Ronald [VU University Medical Centre, Department of Radiology and Nuclear Medicine, Amsterdam (Netherlands); Scheffler, Matthias; Wolf, Juergen [University Hospital of Cologne, Lung Cancer Group Cologne, Department I of Internal Medicine, Center for Integrated Oncology Cologne Bonn, Cologne (Germany)

    2016-02-15

    In oncological imaging using PET/CT, the standardized uptake value has become the most common parameter used to measure tracer accumulation. The aim of this analysis was to evaluate ultra high definition (UHD) and ordered subset expectation maximization (OSEM) PET/CT reconstructions for their potential impact on quantification. We analyzed 40 PET/CT scans of lung cancer patients who had undergone PET/CT. Standardized uptake values corrected for body weight (SUV) and lean body mass (SUL) were determined in the single hottest lesion in the lung and normalized to the liver for UHD and OSEM reconstruction. Quantitative uptake values and their normalized ratios for the two reconstruction settings were compared using the Wilcoxon test. The distribution of quantitative uptake values and their ratios in relation to the reconstruction method used were demonstrated in the form of frequency distribution curves, box-plots and scatter plots. The agreement between OSEM and UHD reconstructions was assessed through Bland-Altman analysis. A significant difference was observed after OSEM and UHD reconstruction for SUV and SUL data tested (p < 0.0005 in all cases). The mean values of the ratios after OSEM and UHD reconstruction showed equally significant differences (p < 0.0005 in all cases). Bland-Altman analysis showed that the SUV and SUL and their normalized values were, on average, up to 60 % higher after UHD reconstruction as compared to OSEM reconstruction. OSEM and HD reconstruction brought a significant difference for SUV and SUL, which remained constantly high after normalization to the liver, indicating that standardization of reconstruction and the use of comparable SUV measurements are crucial when using PET/CT. (orig.)

  3. The impact of reconstruction method on the quantification of DaTSCAN images

    Energy Technology Data Exchange (ETDEWEB)

    Dickson, John C.; Erlandsson, Kjell; Hutton, Brian F. [UCLH NHS Foundation Trust and University College London, Institute of Nuclear Medicine, London (United Kingdom); Tossici-Bolt, Livia [Southampton University Hospitals NHS Trust, Department of Medical Physics, Southampton (United Kingdom); Sera, Terez [University of Szeged, Department of Nuclear Medicine and Euromedic Szeged, Szeged (Hungary); Varrone, Andrea [Psychiatry Section and Stockholm Brain Institute, Karolinska Institute, Department of Clinical Neuroscience, Stockholm (Sweden); Tatsch, Klaus [EANM/European Network of Excellence for Brain Imaging, Vienna (Austria)

    2010-01-15

    Reconstruction of DaTSCAN brain studies using OS-EM iterative reconstruction offers better image quality and more accurate quantification than filtered back-projection. However, reconstruction must proceed for a sufficient number of iterations to achieve stable and accurate data. This study assessed the impact of the number of iterations on the image quantification, comparing the results of the iterative reconstruction with filtered back-projection data. A striatal phantom filled with {sup 123}I using striatal to background ratios between 2:1 and 10:1 was imaged on five different gamma camera systems. Data from each system were reconstructed using OS-EM (which included depth-independent resolution recovery) with various combinations of iterations and subsets to achieve up to 200 EM-equivalent iterations and with filtered back-projection. Using volume of interest analysis, the relationships between image reconstruction strategy and quantification of striatal uptake were assessed. For phantom filling ratios of 5:1 or less, significant convergence of measured ratios occurred close to 100 EM-equivalent iterations, whereas for higher filling ratios, measured uptake ratios did not display a convergence pattern. Assessment of the count concentrations used to derive the measured uptake ratio showed that nonconvergence of low background count concentrations caused peaking in higher measured uptake ratios. Compared to filtered back-projection, OS-EM displayed larger uptake ratios because of the resolution recovery applied in the iterative algorithm. The number of EM-equivalent iterations used in OS-EM reconstruction influences the quantification of DaTSCAN studies because of incomplete convergence and possible bias in areas of low activity due to the nonnegativity constraint in OS-EM reconstruction. Nevertheless, OS-EM using 100 EM-equivalent iterations provides the best linear discriminatory measure to quantify the uptake in DaTSCAN studies. (orig.)

  4. A new reconstruction strategy for image improvement in pinhole SPECT

    International Nuclear Information System (INIS)

    Zeniya, Tsutomu; Watabe, Hiroshi; Kim, Kyeong Min; Teramoto, Noboru; Hayashi, Takuya; Iida, Hidehiro; Aoi, Toshiyuki; Sohlberg, Antti; Kudo, Hiroyuki

    2004-01-01

    Pinhole single-photon emission computed tomography (SPECT) is able to provide information on the biodistribution of several radioligands in small laboratory animals, but has limitations associated with non-uniform spatial resolution or axial blurring. We have hypothesised that this blurring is due to incompleteness of the projection data acquired by a single circular pinhole orbit, and have evaluated a new strategy for accurate image reconstruction with better spatial resolution uniformity. A pinhole SPECT system using two circular orbits and a dedicated three-dimensional ordered subsets expectation maximisation (3D-OSEM) reconstruction method were developed. In this system, not the camera but the object rotates, and the two orbits are at 90 and 45 relative to the object's axis. This system satisfies Tuy's condition, and is thus able to provide complete data for 3D pinhole SPECT reconstruction within the whole field of view (FOV). To evaluate this system, a series of experiments was carried out using a multiple-disk phantom filled with 99m Tc solution. The feasibility of the proposed method for small animal imaging was tested with a mouse bone study using 99m Tc-hydroxymethylene diphosphonate. Feldkamp's filtered back-projection (FBP) method and the 3D-OSEM method were applied to these data sets, and the visual and statistical properties were examined. Axial blurring, which was still visible at the edge of the FOV even after applying the conventional 3D-OSEM instead of FBP for single-orbit data, was not visible after application of 3D-OSEM using two-orbit data. 3D-OSEM using two-orbit data dramatically reduced the resolution non-uniformity and statistical noise, and also demonstrated considerably better image quality in the mouse scan. This system may be of use in quantitative assessment of bio-physiological functions in small animals. (orig.)

  5. High spatial resolution CT image reconstruction using parallel computing

    International Nuclear Information System (INIS)

    Yin Yin; Liu Li; Sun Gongxing

    2003-01-01

    Using the PC cluster system with 16 dual CPU nodes, we accelerate the FBP and OR-OSEM reconstruction of high spatial resolution image (2048 x 2048). Based on the number of projections, we rewrite the reconstruction algorithms into parallel format and dispatch the tasks to each CPU. By parallel computing, the speedup factor is roughly equal to the number of CPUs, which can be up to about 25 times when 25 CPUs used. This technique is very suitable for real-time high spatial resolution CT image reconstruction. (authors)

  6. Fast GPU-based Monte Carlo code for SPECT/CT reconstructions generates improved 177Lu images.

    Science.gov (United States)

    Rydén, T; Heydorn Lagerlöf, J; Hemmingsson, J; Marin, I; Svensson, J; Båth, M; Gjertsson, P; Bernhardt, P

    2018-01-04

    Full Monte Carlo (MC)-based SPECT reconstructions have a strong potential for correcting for image degrading factors, but the reconstruction times are long. The objective of this study was to develop a highly parallel Monte Carlo code for fast, ordered subset expectation maximum (OSEM) reconstructions of SPECT/CT images. The MC code was written in the Compute Unified Device Architecture language for a computer with four graphics processing units (GPUs) (GeForce GTX Titan X, Nvidia, USA). This enabled simulations of parallel photon emissions from the voxels matrix (128 3 or 256 3 ). Each computed tomography (CT) number was converted to attenuation coefficients for photo absorption, coherent scattering, and incoherent scattering. For photon scattering, the deflection angle was determined by the differential scattering cross sections. An angular response function was developed and used to model the accepted angles for photon interaction with the crystal, and a detector scattering kernel was used for modeling the photon scattering in the detector. Predefined energy and spatial resolution kernels for the crystal were used. The MC code was implemented in the OSEM reconstruction of clinical and phantom 177 Lu SPECT/CT images. The Jaszczak image quality phantom was used to evaluate the performance of the MC reconstruction in comparison with attenuated corrected (AC) OSEM reconstructions and attenuated corrected OSEM reconstructions with resolution recovery corrections (RRC). The performance of the MC code was 3200 million photons/s. The required number of photons emitted per voxel to obtain a sufficiently low noise level in the simulated image was 200 for a 128 3 voxel matrix. With this number of emitted photons/voxel, the MC-based OSEM reconstruction with ten subsets was performed within 20 s/iteration. The images converged after around six iterations. Therefore, the reconstruction time was around 3 min. The activity recovery for the spheres in the Jaszczak phantom was

  7. Effect of Post-Reconstruction Gaussian Filtering on Image Quality and Myocardial Blood Flow Measurement with N-13 Ammonia PET

    International Nuclear Information System (INIS)

    Kim, Hyeon Sik; Cho, Sang-Geon; Kim, Ju Han; Kwon, Seong Young; Lee, Byeong-il; Bom, Hee-Seung

    2014-01-01

    In order to evaluate the effect of post-reconstruction Gaussian filtering on image quality and myocardial blood flow (MBF) measurement by dynamic N-13 ammonia positron emission tomography (PET), we compared various reconstruction and filtering methods with image characteristics. Dynamic PET images of three patients with coronary artery disease (male-female ratio of 2:1; age: 57, 53, and 76 years) were reconstructed, using filtered back projection (FBP) and ordered subset expectation maximization (OSEM) methods. OSEM reconstruction consisted of OSEM-2I, OSEM-4I, and OSEM-6I with 2, 4, and 6 iterations, respectively. The images, reconstructed and filtered by Gaussian filters of 5, 10, and 15 mm, were obtained, as well as non-filtered images. Visual analysis of image quality (IQ) was performed using a 3-grade scoring system by 2 independent readers, blinded to the reconstruction and filtering methods of stress images. Then, signal-to-noise ratio (SNR) was calculated by noise and contrast recovery (CR). Stress and rest MBF and coronary flow reserve (CFR) were obtained for each method. IQ scores, stress and rest MBF, and CFR were compared between the methods, using Chi-square and Kruskal-Wallis tests. In the visual analysis, IQ was significantly higher by 10 mm Gaussian filtering, compared to other sizes of filter (P<0.001 for both readers). However, no significant difference of IQ was found between FBP and various numbers of iteration in OSEM (P=0.923 and 0.855 for readers 1 and 2, respectively). SNR was significantly higher in 10 mm Gaussian filter. There was a significant difference in stress and rest MBF between several vascular territories. However CFR was not significantly different according to various filtering methods. Post-reconstruction Gaussian filtering with a filter size of 10 mm significantly enhances the IQ of N-13 ammonia PET-CT, without changing the results of CFR calculation

  8. Reduction of artefacts due to missing projections using OSEM

    International Nuclear Information System (INIS)

    Hutton, B.F.; Kyme, A.; Choong, K.

    2002-01-01

    Full text: It is well recognised that missing or corrupted projections can result in artefacts. This occasionally occurs due to errors in data transfer from acquisition memory to disk. A possible approach for reducing these artefacts was investigated, Using ordered subsets expectation maximization (OSEM) the iterative reconstruction proceeds by progressively including additional projections until a single iteration is complete. Clinically useful results can be obtained using a small subset size in a single iteration. Stopping prior to the complete iteration so as to avoid inclusion of missing or corrupted data should provide a 'partial' reconstruction with minimal artefacts. To test this hypothesis projections were selectively removed from a complete data set (2, 4, 8, 12 adjacent projections) and reconstructions were performed using both filtered back projection (FBP) and OSEM. To maintain a constant number of sub-iterations in OSEM an equal number of duplicate projections were substituted for the missing projections. Both 180 and 360 degrees reconstructions with missing data were compared with reconstruction for the complete data using sum of absolute differences. Results indicate that missing data causes artefacts for both FBP and OSEM however the severity of artefacts is significantly reduced using OSEM. The effect of missing data is generally greater for 180 degrees acquisition. OSEM is recommended for minimising reconstruction artefacts due to missing projections. Copyright (2002) The Australian and New Zealand Society of Nuclear Medicine Inc

  9. The SRT reconstruction algorithm for semiquantification in PET imaging

    Energy Technology Data Exchange (ETDEWEB)

    Kastis, George A., E-mail: gkastis@academyofathens.gr [Research Center of Mathematics, Academy of Athens, Athens 11527 (Greece); Gaitanis, Anastasios [Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens 11527 (Greece); Samartzis, Alexandros P. [Nuclear Medicine Department, Evangelismos General Hospital, Athens 10676 (Greece); Fokas, Athanasios S. [Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Cambridge CB30WA, United Kingdom and Research Center of Mathematics, Academy of Athens, Athens 11527 (Greece)

    2015-10-15

    Purpose: The spline reconstruction technique (SRT) is a new, fast algorithm based on a novel numerical implementation of an analytic representation of the inverse Radon transform. The mathematical details of this algorithm and comparisons with filtered backprojection were presented earlier in the literature. In this study, the authors present a comparison between SRT and the ordered-subsets expectation–maximization (OSEM) algorithm for determining contrast and semiquantitative indices of {sup 18}F-FDG uptake. Methods: The authors implemented SRT in the software for tomographic image reconstruction (STIR) open-source platform and evaluated this technique using simulated and real sinograms obtained from the GE Discovery ST positron emission tomography/computer tomography scanner. All simulations and reconstructions were performed in STIR. For OSEM, the authors used the clinical protocol of their scanner, namely, 21 subsets and two iterations. The authors also examined images at one, four, six, and ten iterations. For the simulation studies, the authors analyzed an image-quality phantom with cold and hot lesions. Two different versions of the phantom were employed at two different hot-sphere lesion-to-background ratios (LBRs), namely, 2:1 and 4:1. For each noiseless sinogram, 20 Poisson realizations were created at five different noise levels. In addition to making visual comparisons of the reconstructed images, the authors determined contrast and bias as a function of the background image roughness (IR). For the real-data studies, sinograms of an image-quality phantom simulating the human torso were employed. The authors determined contrast and LBR as a function of the background IR. Finally, the authors present plots of contrast as a function of IR after smoothing each reconstructed image with Gaussian filters of six different sizes. Statistical significance was determined by employing the Wilcoxon rank-sum test. Results: In both simulated and real studies, SRT

  10. The SRT reconstruction algorithm for semiquantification in PET imaging

    International Nuclear Information System (INIS)

    Kastis, George A.; Gaitanis, Anastasios; Samartzis, Alexandros P.; Fokas, Athanasios S.

    2015-01-01

    Purpose: The spline reconstruction technique (SRT) is a new, fast algorithm based on a novel numerical implementation of an analytic representation of the inverse Radon transform. The mathematical details of this algorithm and comparisons with filtered backprojection were presented earlier in the literature. In this study, the authors present a comparison between SRT and the ordered-subsets expectation–maximization (OSEM) algorithm for determining contrast and semiquantitative indices of 18 F-FDG uptake. Methods: The authors implemented SRT in the software for tomographic image reconstruction (STIR) open-source platform and evaluated this technique using simulated and real sinograms obtained from the GE Discovery ST positron emission tomography/computer tomography scanner. All simulations and reconstructions were performed in STIR. For OSEM, the authors used the clinical protocol of their scanner, namely, 21 subsets and two iterations. The authors also examined images at one, four, six, and ten iterations. For the simulation studies, the authors analyzed an image-quality phantom with cold and hot lesions. Two different versions of the phantom were employed at two different hot-sphere lesion-to-background ratios (LBRs), namely, 2:1 and 4:1. For each noiseless sinogram, 20 Poisson realizations were created at five different noise levels. In addition to making visual comparisons of the reconstructed images, the authors determined contrast and bias as a function of the background image roughness (IR). For the real-data studies, sinograms of an image-quality phantom simulating the human torso were employed. The authors determined contrast and LBR as a function of the background IR. Finally, the authors present plots of contrast as a function of IR after smoothing each reconstructed image with Gaussian filters of six different sizes. Statistical significance was determined by employing the Wilcoxon rank-sum test. Results: In both simulated and real studies, SRT

  11. Effect of Post-Reconstruction Gaussian Filtering on Image Quality and Myocardial Blood Flow Measurement with N-13 Ammonia PET

    Directory of Open Access Journals (Sweden)

    Hyeon Sik Kim

    2014-10-01

    Full Text Available Objective(s: In order to evaluate the effect of post-reconstruction Gaussian filtering on image quality and myocardial blood flow (MBF measurement by dynamic N-13 ammonia positron emission tomography (PET, we compared various reconstruction and filtering methods with image characteristics. Methods: Dynamic PET images of three patients with coronary artery disease (male-female ratio of 2:1; age: 57, 53, and 76 years were reconstructed, using filtered back projection (FBP and ordered subset expectation maximization (OSEM methods. OSEM reconstruction consisted of OSEM_2I, OSEM_4I, and OSEM_6I with 2, 4, and 6 iterations, respectively. The images, reconstructed and filtered by Gaussian filters of 5, 10, and 15 mm, were obtained, as well as non-filtered images. Visual analysis of image quality (IQ was performed using a 3-grade scoring system by 2 independent readers, blinded to the reconstruction and filtering methods of stress images. Then, signal-to-noise ratio (SNR was calculated by noise and contrast recovery (CR. Stress and rest MBF and coronary flow reserve (CFR were obtained for each method. IQ scores, stress and rest MBF, and CFR were compared between the methods, using Chi-square and Kruskal-Wallis tests. Results: In the visual analysis, IQ was significantly higher by 10 mm Gaussian filtering, compared to other sizes of filter (PP=0.923 and 0.855 for readers 1 and 2, respectively. SNR was significantly higher in 10 mm Gaussian filter. There was a significant difference in stress and rest MBF between several vascular territories. However CFR was not significantly different according to various filtering methods. Conclusion: Post-reconstruction Gaussian filtering with a filter size of 10 mm significantly enhances the IQ of N-13 ammonia PET-CT, without changing the results of CFR calculation. .

  12. Pragmatic fully 3D image reconstruction for the MiCES mouse imaging PET scanner

    International Nuclear Information System (INIS)

    Lee, Kisung; Kinahan, Paul E; Fessler, Jeffrey A; Miyaoka, Robert S; Janes, Marie; Lewellen, Tom K

    2004-01-01

    We present a pragmatic approach to image reconstruction for data from the micro crystal elements system (MiCES) fully 3D mouse imaging positron emission tomography (PET) scanner under construction at the University of Washington. Our approach is modelled on fully 3D image reconstruction used in clinical PET scanners, which is based on Fourier rebinning (FORE) followed by 2D iterative image reconstruction using ordered-subsets expectation-maximization (OSEM). The use of iterative methods allows modelling of physical effects (e.g., statistical noise, detector blurring, attenuation, etc), while FORE accelerates the reconstruction process by reducing the fully 3D data to a stacked set of independent 2D sinograms. Previous investigations have indicated that non-stationary detector point-spread response effects, which are typically ignored for clinical imaging, significantly impact image quality for the MiCES scanner geometry. To model the effect of non-stationary detector blurring (DB) in the FORE+OSEM(DB) algorithm, we have added a factorized system matrix to the ASPIRE reconstruction library. Initial results indicate that the proposed approach produces an improvement in resolution without an undue increase in noise and without a significant increase in the computational burden. The impact on task performance, however, remains to be evaluated

  13. Clinical evaluation of iterative reconstruction (ordered-subset expectation maximization) in dynamic positron emission tomography: quantitative effects on kinetic modeling with N-13 ammonia in healthy subjects

    DEFF Research Database (Denmark)

    Hove, Jens Dahlgaard; Rasmussen, R.; Freiberg, J.

    2008-01-01

    emission tomography (PET) studies from 20 normal volunteers at rest and during dipyridamole stimulation were analyzed. Image data were reconstructed with either FBP or OSEM. FBP- and OSEM-derived input functions and tissue curves were compared together with the myocardial blood flow and spillover values...... and OSEM flow values were observed with a flow underestimation of 45% (rest/dipyridamole) in the septum and of 5% (rest) and 15% (dipyridamole) in the lateral myocardial wall. CONCLUSIONS: OSEM reconstruction of myocardial perfusion images with N-13 ammonia and PET produces high-quality images for visual...... interpretation. However, compared with FBP, OSEM is associated with substantial underestimation of perfusion on quantitative imaging. Our findings indicate that OSEM should be used with precaution in clinical PET studies Udgivelsesdato: 2008/7...

  14. Noise and signal properties in PSF-based fully 3D PET image reconstruction: an experimental evaluation

    International Nuclear Information System (INIS)

    Tong, S; Alessio, A M; Kinahan, P E

    2010-01-01

    The addition of accurate system modeling in PET image reconstruction results in images with distinct noise texture and characteristics. In particular, the incorporation of point spread functions (PSF) into the system model has been shown to visually reduce image noise, but the noise properties have not been thoroughly studied. This work offers a systematic evaluation of noise and signal properties in different combinations of reconstruction methods and parameters. We evaluate two fully 3D PET reconstruction algorithms: (1) OSEM with exact scanner line of response modeled (OSEM+LOR), (2) OSEM with line of response and a measured point spread function incorporated (OSEM+LOR+PSF), in combination with the effects of four post-reconstruction filtering parameters and 1-10 iterations, representing a range of clinically acceptable settings. We used a modified NEMA image quality (IQ) phantom, which was filled with 68 Ge and consisted of six hot spheres of different sizes with a target/background ratio of 4:1. The phantom was scanned 50 times in 3D mode on a clinical system to provide independent noise realizations. Data were reconstructed with OSEM+LOR and OSEM+LOR+PSF using different reconstruction parameters, and our implementations of the algorithms match the vendor's product algorithms. With access to multiple realizations, background noise characteristics were quantified with four metrics. Image roughness and the standard deviation image measured the pixel-to-pixel variation; background variability and ensemble noise quantified the region-to-region variation. Image roughness is the image noise perceived when viewing an individual image. At matched iterations, the addition of PSF leads to images with less noise defined as image roughness (reduced by 35% for unfiltered data) and as the standard deviation image, while it has no effect on background variability or ensemble noise. In terms of signal to noise performance, PSF-based reconstruction has a 7% improvement in

  15. Continuous Analog of Accelerated OS-EM Algorithm for Computed Tomography

    Directory of Open Access Journals (Sweden)

    Kiyoko Tateishi

    2017-01-01

    Full Text Available The maximum-likelihood expectation-maximization (ML-EM algorithm is used for an iterative image reconstruction (IIR method and performs well with respect to the inverse problem as cross-entropy minimization in computed tomography. For accelerating the convergence rate of the ML-EM, the ordered-subsets expectation-maximization (OS-EM with a power factor is effective. In this paper, we propose a continuous analog to the power-based accelerated OS-EM algorithm. The continuous-time image reconstruction (CIR system is described by nonlinear differential equations with piecewise smooth vector fields by a cyclic switching process. A numerical discretization of the differential equation by using the geometric multiplicative first-order expansion of the nonlinear vector field leads to an exact equivalent iterative formula of the power-based OS-EM. The convergence of nonnegatively constrained solutions to a globally stable equilibrium is guaranteed by the Lyapunov theorem for consistent inverse problems. We illustrate through numerical experiments that the convergence characteristics of the continuous system have the highest quality compared with that of discretization methods. We clarify how important the discretization method approximates the solution of the CIR to design a better IIR method.

  16. Influence of image reconstruction methods on statistical parametric mapping of brain PET images

    International Nuclear Information System (INIS)

    Yin Dayi; Chen Yingmao; Yao Shulin; Shao Mingzhe; Yin Ling; Tian Jiahe; Cui Hongyan

    2007-01-01

    Objective: Statistic parametric mapping (SPM) was widely recognized as an useful tool in brain function study. The aim of this study was to investigate if imaging reconstruction algorithm of PET images could influence SPM of brain. Methods: PET imaging of whole brain was performed in six normal volunteers. Each volunteer had two scans with true and false acupuncturing. The PET scans were reconstructed using ordered subsets expectation maximization (OSEM) and filtered back projection (FBP) with 3 varied parameters respectively. The images were realigned, normalized and smoothed using SPM program. The difference between true and false acupuncture scans was tested using a matched pair t test at every voxel. Results: (1) SPM corrected multiple comparison (P corrected uncorrected <0.001): SPM derived from the images with different reconstruction method were different. The largest difference, in number and position of the activated voxels, was noticed between FBP and OSEM re- construction algorithm. Conclusions: The method of PET image reconstruction could influence the results of SPM uncorrected multiple comparison. Attention should be paid when the conclusion was drawn using SPM uncorrected multiple comparison. (authors)

  17. Optimization, evaluation, and comparison of standard algorithms for image reconstruction with the VIP-PET.

    Science.gov (United States)

    Mikhaylova, E; Kolstein, M; De Lorenzo, G; Chmeissani, M

    2014-07-01

    A novel positron emission tomography (PET) scanner design based on a room-temperature pixelated CdTe solid-state detector is being developed within the framework of the Voxel Imaging PET (VIP) Pathfinder project [1]. The simulation results show a great potential of the VIP to produce high-resolution images even in extremely challenging conditions such as the screening of a human head [2]. With unprecedented high channel density (450 channels/cm 3 ) image reconstruction is a challenge. Therefore optimization is needed to find the best algorithm in order to exploit correctly the promising detector potential. The following reconstruction algorithms are evaluated: 2-D Filtered Backprojection (FBP), Ordered Subset Expectation Maximization (OSEM), List-Mode OSEM (LM-OSEM), and the Origin Ensemble (OE) algorithm. The evaluation is based on the comparison of a true image phantom with a set of reconstructed images obtained by each algorithm. This is achieved by calculation of image quality merit parameters such as the bias, the variance and the mean square error (MSE). A systematic optimization of each algorithm is performed by varying the reconstruction parameters, such as the cutoff frequency of the noise filters and the number of iterations. The region of interest (ROI) analysis of the reconstructed phantom is also performed for each algorithm and the results are compared. Additionally, the performance of the image reconstruction methods is compared by calculating the modulation transfer function (MTF). The reconstruction time is also taken into account to choose the optimal algorithm. The analysis is based on GAMOS [3] simulation including the expected CdTe and electronic specifics.

  18. Fast GPU-based computation of the sensitivity matrix for a PET list-mode OSEM algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Nassiri, Moulay Ali; Carrier, Jean-Francois [Montreal Univ., QC (Canada). Dept. de Radio-Oncologie; Hissoiny, Sami [Ecole Polytechnique de Montreal, QC (Canada). Dept. de Genie Informatique et Genie Logiciel; Despres, Philippe [Quebec Univ. (Canada). Dept. de Radio-Oncologie

    2011-07-01

    One of the obstacle in introducing a list-mode PET reconstruction algorithm for routine clinical use is the long computation time required for the sensitivity matrix calculation. This matrix must be computed for each study because it depends on the object attenuation map. During the last decade, studies have shown that 3D list-mode OSEM reconstruction algorithms could be effectively performed and considerably accelerated by GPU devices. However, most of that preliminary work (1) was done for pre-clinical PET systems in which the number of LORs is small compared to modern human PET systems and (2) supposed that the sensitivity matrix is pre-calculated. The time required to compute this matrix can however be longer than the reconstruction time itself. The objective of this work is to investigate the performance of sensitivity matrix calculations in terms of computation time with modern GPUs, for clinical fully 3D LM-OSEM for modern PET scanners. For this purpose, sensitivity matrix calculations and full list-mode OSEM reconstruction for human PET systems were implemented on GPUs using the CUDA framework. The system matrices were built on-the-fly by using the multi-ray Siddon algorithm. The time to compute the sensitivity matrix for 288 x 288 x 57 arrays using 3 tangential LORs was 29 seconds. The 3D LM-OSEM algorithm, including the sensitivity matrix calculation, was performed for the same LORs in 71 seconds for 62 millions events, 6 frames and 1 iterations. This work let envision fast reconstructions for advanced PET application such as dynamic studies and parametric image reconstruction. (orig.)

  19. Image Reconstruction. Chapter 13

    Energy Technology Data Exchange (ETDEWEB)

    Nuyts, J. [Department of Nuclear Medicine and Medical Imaging Research Center, Katholieke Universiteit Leuven, Leuven (Belgium); Matej, S. [Medical Image Processing Group, Department of Radiology, University of Pennsylvania, Philadelphia, PA (United States)

    2014-12-15

    This chapter discusses how 2‑D or 3‑D images of tracer distribution can be reconstructed from a series of so-called projection images acquired with a gamma camera or a positron emission tomography (PET) system [13.1]. This is often called an ‘inverse problem’. The reconstruction is the inverse of the acquisition. The reconstruction is called an inverse problem because making software to compute the true tracer distribution from the acquired data turns out to be more difficult than the ‘forward’ direction, i.e. making software to simulate the acquisition. There are basically two approaches to image reconstruction: analytical reconstruction and iterative reconstruction. The analytical approach is based on mathematical inversion, yielding efficient, non-iterative reconstruction algorithms. In the iterative approach, the reconstruction problem is reduced to computing a finite number of image values from a finite number of measurements. That simplification enables the use of iterative instead of mathematical inversion. Iterative inversion tends to require more computer power, but it can cope with more complex (and hopefully more accurate) models of the acquisition process.

  20. Overview of image reconstruction

    International Nuclear Information System (INIS)

    Marr, R.B.

    1980-04-01

    Image reconstruction (or computerized tomography, etc.) is any process whereby a function, f, on R/sup n/ is estimated from empirical data pertaining to its integrals, ∫f(x) dx, for some collection of hyperplanes of dimension k < n. The paper begins with background information on how image reconstruction problems have arisen in practice, and describes some of the application areas of past or current interest; these include radioastronomy, optics, radiology and nuclear medicine, electron microscopy, acoustical imaging, geophysical tomography, nondestructive testing, and NMR zeugmatography. Then the various reconstruction algorithms are discussed in five classes: summation, or simple back-projection; convolution, or filtered back-projection; Fourier and other functional transforms; orthogonal function series expansion; and iterative methods. Certain more technical mathematical aspects of image reconstruction are considered from the standpoint of uniqueness, consistency, and stability of solution. The paper concludes by presenting certain open problems. 73 references

  1. Influences of reconstruction and attenuation correction in brain SPECT images obtained by the hybrid SPECT/CT device: evaluation with a 3-dimensional brain phantom

    International Nuclear Information System (INIS)

    Akamatsu, Mana; Yamashita, Yasuo; Akamatsu, Go; Tsutsui, Yuji; Ohya, Nobuyoshi; Nakamura, Yasuhiko; Sasaki, Masayuki

    2014-01-01

    The aim of this study was to evaluate the influences of reconstruction and attenuation correction on the differences in the radioactivity distributions in 123 I brain SPECT obtained by the hybrid SPECT/CT device. We used the 3-dimensional (3D) brain phantom, which imitates the precise structure of gray matter, white matter and bone regions. It was filled with 123 I solution (20.1 kBq/mL) in the gray matter region and with K 2 HPO 4 in the bone region. The SPECT/CT data were acquired by the hybrid SPECT/CT device. SPECT images were reconstructed by using filtered back projection with uniform attenuation correction (FBP-uAC), 3D ordered-subsets expectation-maximization with uniform AC (3D-OSEM-uAC) and 3D OSEM with CT-based non-uniform AC (3D-OSEM-CTAC). We evaluated the differences in the radioactivity distributions among these reconstruction methods using a 3D digital phantom, which was developed from CT images of the 3D brain phantom, as a reference. The normalized mean square error (NMSE) and regional radioactivity were calculated to evaluate the similarity of SPECT images to the 3D digital phantom. The NMSE values were 0.0811 in FBP-uAC, 0.0914 in 3D-OSEM-uAC and 0.0766 in 3D-OSEM-CTAC. The regional radioactivity of FBP-uAC was 11.5% lower in the middle cerebral artery territory, and that of 3D-OSEM-uAC was 5.8% higher in the anterior cerebral artery territory, compared with the digital phantom. On the other hand, that of 3D-OSEM-CTAC was 1.8% lower in all brain areas. By using the hybrid SPECT/CT device, the brain SPECT reconstructed by 3D-OSEM with CT attenuation correction can provide an accurate assessment of the distribution of brain radioactivity

  2. Clinical evaluation of iterative reconstruction (ordered-subset expectation maximization) in dynamic positron emission tomography: quantitative effects on kinetic modeling with N-13 ammonia in healthy subjects

    DEFF Research Database (Denmark)

    Hove, Jens D; Rasmussen, Rune; Freiberg, Jacob

    2008-01-01

    BACKGROUND: The purpose of this study was to investigate the quantitative properties of ordered-subset expectation maximization (OSEM) on kinetic modeling with nitrogen 13 ammonia compared with filtered backprojection (FBP) in healthy subjects. METHODS AND RESULTS: Cardiac N-13 ammonia positron...... emission tomography (PET) studies from 20 normal volunteers at rest and during dipyridamole stimulation were analyzed. Image data were reconstructed with either FBP or OSEM. FBP- and OSEM-derived input functions and tissue curves were compared together with the myocardial blood flow and spillover values...... and OSEM flow values were observed with a flow underestimation of 45% (rest/dipyridamole) in the septum and of 5% (rest) and 15% (dipyridamole) in the lateral myocardial wall. CONCLUSIONS: OSEM reconstruction of myocardial perfusion images with N-13 ammonia and PET produces high-quality images for visual...

  3. Metal-induced streak artifact reduction using iterative reconstruction algorithms in x-ray computed tomography image of the dentoalveolar region.

    Science.gov (United States)

    Dong, Jian; Hayakawa, Yoshihiko; Kannenberg, Sven; Kober, Cornelia

    2013-02-01

    The objective of this study was to reduce metal-induced streak artifact on oral and maxillofacial x-ray computed tomography (CT) images by developing the fast statistical image reconstruction system using iterative reconstruction algorithms. Adjacent CT images often depict similar anatomical structures in thin slices. So, first, images were reconstructed using the same projection data of an artifact-free image. Second, images were processed by the successive iterative restoration method where projection data were generated from reconstructed image in sequence. Besides the maximum likelihood-expectation maximization algorithm, the ordered subset-expectation maximization algorithm (OS-EM) was examined. Also, small region of interest (ROI) setting and reverse processing were applied for improving performance. Both algorithms reduced artifacts instead of slightly decreasing gray levels. The OS-EM and small ROI reduced the processing duration without apparent detriments. Sequential and reverse processing did not show apparent effects. Two alternatives in iterative reconstruction methods were effective for artifact reduction. The OS-EM algorithm and small ROI setting improved the performance. Copyright © 2012 Elsevier Inc. All rights reserved.

  4. Clinical applications of iterative reconstruction

    International Nuclear Information System (INIS)

    Eberl, S.

    1998-01-01

    Expectation maximisation (EM) reconstruction largely eliminates the hot and cold streaking artifacts characteristic of filtered-back projection (FBP) reconstruction around localised hot areas, such as the bladder. It also substantially reduces the problem of decreased inferior wall counts in MIBI myocardial perfusion studies due to ''streaking'' from high liver uptake. Non-uniform attenuation and scatter correction, resolution recovery, anatomical information, e.g. from MRI or CT tracer kinetic modelling, can all be built into the EM reconstruction imaging model. The properties of ordered subset EM (OSEM) have also been used to correct for known patient motion as part of the reconstruction process. These uses of EM are elaborated more fully in some of the other abstracts of this meeting. Currently we use OSEM routinely for: (i) studies where streaking is a problem, including all MIBI myocardial perfusion studies, to avoid hot liver inferior wall artifact, (ii) all whole body FDG PET, all lung V/Q SPECT (which have a short acquisition time) and all gated 201 TI myocardial perfusion studies due to improved noise characteristics of OSEM in these studies; (iii) studies with measured, non-uniform attenuation correction. With the accelerated OSEM algorithm, iterative reconstruction is practical for routine clinical applications and we have found OSEM to provide clearly superior reconstructions for the areas listed above and are investigating its application to other studies. In clinical use, we have not found OSEM to introduce artifacts which would not also occur with FBP, e.g. uncorrected patient motion will cause artifacts with both OSEM and FBP

  5. Clinical evaluation of PET image reconstruction using a spatial resolution model

    DEFF Research Database (Denmark)

    Andersen, Flemming Littrup; Klausen, Thomas Levin; Loft, Annika

    2013-01-01

    PURPOSE: PET image resolution is variable across the measured field-of-view and described by the point spread function (PSF). When accounting for the PSF during PET image reconstruction image resolution is improved and partial volume effects are reduced. Here, we evaluate the effect of PSF......-based reconstruction on lesion quantification in routine clinical whole-body (WB) PET/CT imaging. MATERIALS AND METHODS: 41 oncology patients were referred for a WB-PET/CT examination (Biograph 40 TruePoint). Emission data were acquired at 2.5min/bed at 1hpi of 400 MBq [18F]-FDG. Attenuation-corrected PET images were...... reconstructed on 336×336-matrices using: (R1) standard AW-OSEM (4 iter, 8 subsets, 4mm Gaussian) and (R2) AW-OSEM with PSF (3 iter, 21 subsets, 2mm). Blinded and randomised reading of R1- and R2-PET images was performed. Individual lesions were located and counted independently on both sets of images...

  6. Accelerating image reconstruction in dual-head PET system by GPU and symmetry properties.

    Directory of Open Access Journals (Sweden)

    Cheng-Ying Chou

    Full Text Available Positron emission tomography (PET is an important imaging modality in both clinical usage and research studies. We have developed a compact high-sensitivity PET system that consisted of two large-area panel PET detector heads, which produce more than 224 million lines of response and thus request dramatic computational demands. In this work, we employed a state-of-the-art graphics processing unit (GPU, NVIDIA Tesla C2070, to yield an efficient reconstruction process. Our approaches ingeniously integrate the distinguished features of the symmetry properties of the imaging system and GPU architectures, including block/warp/thread assignments and effective memory usage, to accelerate the computations for ordered subset expectation maximization (OSEM image reconstruction. The OSEM reconstruction algorithms were implemented employing both CPU-based and GPU-based codes, and their computational performance was quantitatively analyzed and compared. The results showed that the GPU-accelerated scheme can drastically reduce the reconstruction time and thus can largely expand the applicability of the dual-head PET system.

  7. Direct parametric reconstruction in dynamic PET myocardial perfusion imaging: in vivo studies

    Science.gov (United States)

    Petibon, Yoann; Rakvongthai, Yothin; El Fakhri, Georges; Ouyang, Jinsong

    2017-05-01

    Dynamic PET myocardial perfusion imaging (MPI) used in conjunction with tracer kinetic modeling enables the quantification of absolute myocardial blood flow (MBF). However, MBF maps computed using the traditional indirect method (i.e. post-reconstruction voxel-wise fitting of kinetic model to PET time-activity-curves-TACs) suffer from poor signal-to-noise ratio (SNR). Direct reconstruction of kinetic parameters from raw PET projection data has been shown to offer parametric images with higher SNR compared to the indirect method. The aim of this study was to extend and evaluate the performance of a direct parametric reconstruction method using in vivo dynamic PET MPI data for the purpose of quantifying MBF. Dynamic PET MPI studies were performed on two healthy pigs using a Siemens Biograph mMR scanner. List-mode PET data for each animal were acquired following a bolus injection of ~7-8 mCi of 18F-flurpiridaz, a myocardial perfusion agent. Fully-3D dynamic PET sinograms were obtained by sorting the coincidence events into 16 temporal frames covering ~5 min after radiotracer administration. Additionally, eight independent noise realizations of both scans—each containing 1/8th of the total number of events—were generated from the original list-mode data. Dynamic sinograms were then used to compute parametric maps using the conventional indirect method and the proposed direct method. For both methods, a one-tissue compartment model accounting for spillover from the left and right ventricle blood-pools was used to describe the kinetics of 18F-flurpiridaz. An image-derived arterial input function obtained from a TAC taken in the left ventricle cavity was used for tracer kinetic analysis. For the indirect method, frame-by-frame images were estimated using two fully-3D reconstruction techniques: the standard ordered subset expectation maximization (OSEM) reconstruction algorithm on one side, and the one-step late maximum a posteriori (OSL-MAP) algorithm on the other

  8. Direct parametric reconstruction in dynamic PET myocardial perfusion imaging: in-vivo studies

    Science.gov (United States)

    Petibon, Yoann; Rakvongthai, Yothin; Fakhri, Georges El; Ouyang, Jinsong

    2017-01-01

    Dynamic PET myocardial perfusion imaging (MPI) used in conjunction with tracer kinetic modeling enables the quantification of absolute myocardial blood flow (MBF). However, MBF maps computed using the traditional indirect method (i.e. post-reconstruction voxel-wise fitting of kinetic model to PET time-activity-curves -TACs) suffer from poor signal-to-noise ratio (SNR). Direct reconstruction of kinetic parameters from raw PET projection data has been shown to offer parametric images with higher SNR compared to the indirect method. The aim of this study was to extend and evaluate the performance of a direct parametric reconstruction method using in-vivo dynamic PET MPI data for the purpose of quantifying MBF. Dynamic PET MPI studies were performed on two healthy pigs using a Siemens Biograph mMR scanner. List-mode PET data for each animal were acquired following a bolus injection of ~7-8 mCi of 18F-flurpiridaz, a myocardial perfusion agent. Fully-3D dynamic PET sinograms were obtained by sorting the coincidence events into 16 temporal frames covering ~5 min after radiotracer administration. Additionally, eight independent noise realizations of both scans - each containing 1/8th of the total number of events - were generated from the original list-mode data. Dynamic sinograms were then used to compute parametric maps using the conventional indirect method and the proposed direct method. For both methods, a one-tissue compartment model accounting for spillover from the left and right ventricle blood-pools was used to describe the kinetics of 18F-flurpiridaz. An image-derived arterial input function obtained from a TAC taken in the left ventricle cavity was used for tracer kinetic analysis. For the indirect method, frame-by-frame images were estimated using two fully-3D reconstruction techniques: the standard Ordered Subset Expectation Maximization (OSEM) reconstruction algorithm on one side, and the One-Step Late Maximum a Posteriori (OSL-MAP) algorithm on the other

  9. The effect of 18F-FDG-PET image reconstruction algorithms on the expression of characteristic metabolic brain network in Parkinson's disease.

    Science.gov (United States)

    Tomše, Petra; Jensterle, Luka; Rep, Sebastijan; Grmek, Marko; Zaletel, Katja; Eidelberg, David; Dhawan, Vijay; Ma, Yilong; Trošt, Maja

    2017-09-01

    To evaluate the reproducibility of the expression of Parkinson's Disease Related Pattern (PDRP) across multiple sets of 18F-FDG-PET brain images reconstructed with different reconstruction algorithms. 18F-FDG-PET brain imaging was performed in two independent cohorts of Parkinson's disease (PD) patients and normal controls (NC). Slovenian cohort (20 PD patients, 20 NC) was scanned with Siemens Biograph mCT camera and reconstructed using FBP, FBP+TOF, OSEM, OSEM+TOF, OSEM+PSF and OSEM+PSF+TOF. American Cohort (20 PD patients, 7 NC) was scanned with GE Advance camera and reconstructed using 3DRP, FORE-FBP and FORE-Iterative. Expressions of two previously-validated PDRP patterns (PDRP-Slovenia and PDRP-USA) were calculated. We compared the ability of PDRP to discriminate PD patients from NC, differences and correlation between the corresponding subject scores and ROC analysis results across the different reconstruction algorithms. The expression of PDRP-Slovenia and PDRP-USA networks was significantly elevated in PD patients compared to NC (palgorithms. PDRP expression strongly correlated between all studied algorithms and the reference algorithm (r⩾0.993, palgorithms varied within 0.73 and 0.08 of the reference value for PDRP-Slovenia and PDRP-USA, respectively. ROC analysis confirmed high similarity in sensitivity, specificity and AUC among all studied reconstruction algorithms. These results show that the expression of PDRP is reproducible across a variety of reconstruction algorithms of 18F-FDG-PET brain images. PDRP is capable of providing a robust metabolic biomarker of PD for multicenter 18F-FDG-PET images acquired in the context of differential diagnosis or clinical trials. Copyright © 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  10. Quantification of dopaminergic neurotransmission SPECT studies with 123I-labelled radioligands. A comparison between different imaging systems and data acquisition protocols using Monte Carlo simulation

    International Nuclear Information System (INIS)

    Crespo, Cristina; Aguiar, Pablo; Gallego, Judith; Cot, Albert; Falcon, Carles; Ros, Domenec; Bullich, Santiago; Pareto, Deborah; Sempau, Josep; Lomena, Francisco; Calvino, Francisco; Pavia, Javier

    2008-01-01

    123 I-labelled radioligands are commonly used for single-photon emission computed tomography (SPECT) imaging of the dopaminergic system to study the dopamine transporter binding. The aim of this work was to compare the quantitative capabilities of two different SPECT systems through Monte Carlo (MC) simulation. The SimSET MC code was employed to generate simulated projections of a numerical phantom for two gamma cameras equipped with a parallel and a fan-beam collimator, respectively. A fully 3D iterative reconstruction algorithm was used to compensate for attenuation, the spatially variant point spread function (PSF) and scatter. A post-reconstruction partial volume effect (PVE) compensation was also developed. For both systems, the correction for all degradations and PVE compensation resulted in recovery factors of the theoretical specific uptake ratio (SUR) close to 100%. For a SUR value of 4, the recovered SUR for the parallel imaging system was 33% for a reconstruction without corrections (OSEM), 45% for a reconstruction with attenuation correction (OSEM-A), 56% for a 3D reconstruction with attenuation and PSF corrections (OSEM-AP), 68% for OSEM-AP with scatter correction (OSEM-APS) and 97% for OSEM-APS plus PVE compensation (OSEM-APSV). For the fan-beam imaging system, the recovered SUR was 41% without corrections, 55% for OSEM-A, 65% for OSEM-AP, 75% for OSEM-APS and 102% for OSEM-APSV. Our findings indicate that the correction for degradations increases the quantification accuracy, with PVE compensation playing a major role in the SUR quantification. The proposed methodology allows us to reach similar SUR values for different SPECT systems, thereby allowing a reliable standardisation in multicentric studies. (orig.)

  11. Quantification of dopaminergic neurotransmission SPECT studies with {sup 123}I-labelled radioligands. A comparison between different imaging systems and data acquisition protocols using Monte Carlo simulation

    Energy Technology Data Exchange (ETDEWEB)

    Crespo, Cristina; Aguiar, Pablo [Universitat de Barcelona - IDIBAPS, Unitat de Biofisica i Bioenginyeria, Departament de Ciencies Fisiologiques I, Facultat de Medicina, Barcelona (Spain); Gallego, Judith [Universitat Politecnica de Catalunya, Institut de Tecniques Energetiques, Barcelona (Spain); Institut de Bioenginyeria de Catalunya, Barcelona (Spain); Cot, Albert [Universitat de Barcelona - IDIBAPS, Unitat de Biofisica i Bioenginyeria, Departament de Ciencies Fisiologiques I, Facultat de Medicina, Barcelona (Spain); Universitat Politecnica de Catalunya, Seccio d' Enginyeria Nuclear, Departament de Fisica i Enginyeria Nuclear, Barcelona (Spain); Falcon, Carles; Ros, Domenec [Universitat de Barcelona - IDIBAPS, Unitat de Biofisica i Bioenginyeria, Departament de Ciencies Fisiologiques I, Facultat de Medicina, Barcelona (Spain); CIBER en Bioingenieria, Biomateriales y Nanomedicina (CIBER-BBN), Barcelona (Spain); Bullich, Santiago [Hospital del Mar, Center for Imaging in Psychiatry, CRC-MAR, Barcelona (Spain); Pareto, Deborah [CIBER en Bioingenieria, Biomateriales y Nanomedicina (CIBER-BBN), Barcelona (Spain); PRBB, Institut d' Alta Tecnologia, Barcelona (Spain); Sempau, Josep [Universitat Politecnica de Catalunya, Institut de Tecniques Energetiques, Barcelona (Spain); CIBER en Bioingenieria, Biomateriales y Nanomedicina (CIBER-BBN), Barcelona (Spain); Lomena, Francisco [IDIBAPS, Servei de Medicina Nuclear, Hospital Clinic, Barcelona (Spain); Calvino, Francisco [Universitat Politecnica de Catalunya, Institut de Tecniques Energetiques, Barcelona (Spain); Universitat Politecnica de Catalunya, Seccio d' Enginyeria Nuclear, Departament de Fisica i Enginyeria Nuclear, Barcelona (Spain); Pavia, Javier [CIBER en Bioingenieria, Biomateriales y Nanomedicina (CIBER-BBN), Barcelona (Spain); IDIBAPS, Servei de Medicina Nuclear, Hospital Clinic, Barcelona (Spain)

    2008-07-15

    {sup 123}I-labelled radioligands are commonly used for single-photon emission computed tomography (SPECT) imaging of the dopaminergic system to study the dopamine transporter binding. The aim of this work was to compare the quantitative capabilities of two different SPECT systems through Monte Carlo (MC) simulation. The SimSET MC code was employed to generate simulated projections of a numerical phantom for two gamma cameras equipped with a parallel and a fan-beam collimator, respectively. A fully 3D iterative reconstruction algorithm was used to compensate for attenuation, the spatially variant point spread function (PSF) and scatter. A post-reconstruction partial volume effect (PVE) compensation was also developed. For both systems, the correction for all degradations and PVE compensation resulted in recovery factors of the theoretical specific uptake ratio (SUR) close to 100%. For a SUR value of 4, the recovered SUR for the parallel imaging system was 33% for a reconstruction without corrections (OSEM), 45% for a reconstruction with attenuation correction (OSEM-A), 56% for a 3D reconstruction with attenuation and PSF corrections (OSEM-AP), 68% for OSEM-AP with scatter correction (OSEM-APS) and 97% for OSEM-APS plus PVE compensation (OSEM-APSV). For the fan-beam imaging system, the recovered SUR was 41% without corrections, 55% for OSEM-A, 65% for OSEM-AP, 75% for OSEM-APS and 102% for OSEM-APSV. Our findings indicate that the correction for degradations increases the quantification accuracy, with PVE compensation playing a major role in the SUR quantification. The proposed methodology allows us to reach similar SUR values for different SPECT systems, thereby allowing a reliable standardisation in multicentric studies. (orig.)

  12. Fully 3D iterative scatter-corrected OSEM for HRRT PET using a GPU

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Kyung Sang; Ye, Jong Chul, E-mail: kssigari@kaist.ac.kr, E-mail: jong.ye@kaist.ac.kr [Bio-Imaging and Signal Processing Lab., Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), 335 Gwahak-no, Yuseong-gu, Daejon 305-701 (Korea, Republic of)

    2011-08-07

    Accurate scatter correction is especially important for high-resolution 3D positron emission tomographies (PETs) such as high-resolution research tomograph (HRRT) due to large scatter fraction in the data. To address this problem, a fully 3D iterative scatter-corrected ordered subset expectation maximization (OSEM) in which a 3D single scatter simulation (SSS) is alternatively performed with a 3D OSEM reconstruction was recently proposed. However, due to the computational complexity of both SSS and OSEM algorithms for a high-resolution 3D PET, it has not been widely used in practice. The main objective of this paper is, therefore, to accelerate the fully 3D iterative scatter-corrected OSEM using a graphics processing unit (GPU) and verify its performance for an HRRT. We show that to exploit the massive thread structures of the GPU, several algorithmic modifications are necessary. For SSS implementation, a sinogram-driven approach is found to be more appropriate compared to a detector-driven approach, as fast linear interpolation can be performed in the sinogram domain through the use of texture memory. Furthermore, a pixel-driven backprojector and a ray-driven projector can be significantly accelerated by assigning threads to voxels and sinograms, respectively. Using Nvidia's GPU and compute unified device architecture (CUDA), the execution time of a SSS is less than 6 s, a single iteration of OSEM with 16 subsets takes 16 s, and a single iteration of the fully 3D scatter-corrected OSEM composed of a SSS and six iterations of OSEM takes under 105 s for the HRRT geometry, which corresponds to acceleration factors of 125x and 141x for OSEM and SSS, respectively. The fully 3D iterative scatter-corrected OSEM algorithm is validated in simulations using Geant4 application for tomographic emission and in actual experiments using an HRRT.

  13. Edge Artifacts in Point Spread Function-based PET Reconstruction in Relation to Object Size and Reconstruction Parameters

    Directory of Open Access Journals (Sweden)

    Yuji Tsutsui

    2017-06-01

    Full Text Available Objective(s: We evaluated edge artifacts in relation to phantom diameter and reconstruction parameters in point spread function (PSF-based positron emission tomography (PET image reconstruction.Methods: PET data were acquired from an original cone-shaped phantom filled with 18F solution (21.9 kBq/mL for 10 min using a Biograph mCT scanner. The images were reconstructed using the baseline ordered subsets expectation maximization (OSEM algorithm and the OSEM with PSF correction model. The reconstruction parameters included a pixel size of 1.0, 2.0, or 3.0 mm, 1-12 iterations, 24 subsets, and a full width at half maximum (FWHM of the post-filter Gaussian filter of 1.0, 2.0, or 3.0 mm. We compared both the maximum recovery coefficient (RCmax and the mean recovery coefficient (RCmean in the phantom at different diameters.Results: The OSEM images had no edge artifacts, but the OSEM with PSF images had a dense edge delineating the hot phantom at diameters 10 mm or more and a dense spot at the center at diameters of 8 mm or less. The dense edge was clearly observed on images with a small pixel size, a Gaussian filter with a small FWHM, and a high number of iterations. At a phantom diameter of 6-7 mm, the RCmax for the OSEM and OSEM with PSF images was 60% and 140%, respectively (pixel size: 1.0 mm; FWHM of the Gaussian filter: 2.0 mm; iterations: 2. The RCmean of the OSEM with PSF images did not exceed 100%.Conclusion: PSF-based image reconstruction resulted in edge artifacts, the degree of which depends on the pixel size, number of iterations, FWHM of the Gaussian filter, and object size.

  14. LOR-interleaving image reconstruction for PET imaging with fractional-crystal collimation

    International Nuclear Information System (INIS)

    Li, Yusheng; Matej, Samuel; Karp, Joel S; Metzler, Scott D

    2015-01-01

    Positron emission tomography (PET) has become an important modality in medical and molecular imaging. However, in most PET applications, the resolution is still mainly limited by the physical crystal sizes or the detector’s intrinsic spatial resolution. To achieve images with better spatial resolution in a central region of interest (ROI), we have previously proposed using collimation in PET scanners. The collimator is designed to partially mask detector crystals to detect lines of response (LORs) within fractional crystals. A sequence of collimator-encoded LORs is measured with different collimation configurations. This novel collimated scanner geometry makes the reconstruction problem challenging, as both detector and collimator effects need to be modeled to reconstruct high-resolution images from collimated LORs. In this paper, we present a LOR-interleaving (LORI) algorithm, which incorporates these effects and has the advantage of reusing existing reconstruction software, to reconstruct high-resolution images for PET with fractional-crystal collimation. We also develop a 3D ray-tracing model incorporating both the collimator and crystal penetration for simulations and reconstructions of the collimated PET. By registering the collimator-encoded LORs with the collimator configurations, high-resolution LORs are restored based on the modeled transfer matrices using the non-negative least-squares method and EM algorithm. The resolution-enhanced images are then reconstructed from the high-resolution LORs using the MLEM or OSEM algorithm. For validation, we applied the LORI method to a small-animal PET scanner, A-PET, with a specially designed collimator. We demonstrate through simulated reconstructions with a hot-rod phantom and MOBY phantom that the LORI reconstructions can substantially improve spatial resolution and quantification compared to the uncollimated reconstructions. The LORI algorithm is crucial to improve overall image quality of collimated PET, which

  15. PET image reconstruction with rotationally symmetric polygonal pixel grid based highly compressible system matrix

    International Nuclear Information System (INIS)

    Yu Yunhan; Xia Yan; Liu Yaqiang; Wang Shi; Ma Tianyu; Chen Jing; Hong Baoyu

    2013-01-01

    To achieve a maximum compression of system matrix in positron emission tomography (PET) image reconstruction, we proposed a polygonal image pixel division strategy in accordance with rotationally symmetric PET geometry. Geometrical definition and indexing rule for polygonal pixels were established. Image conversion from polygonal pixel structure to conventional rectangular pixel structure was implemented using a conversion matrix. A set of test images were analytically defined in polygonal pixel structure, converted to conventional rectangular pixel based images, and correctly displayed which verified the correctness of the image definition, conversion description and conversion of polygonal pixel structure. A compressed system matrix for PET image recon was generated by tap model and tested by forward-projecting three different distributions of radioactive sources to the sinogram domain and comparing them with theoretical predictions. On a practical small animal PET scanner, a compress ratio of 12.6:1 of the system matrix size was achieved with the polygonal pixel structure, comparing with the conventional rectangular pixel based tap-mode one. OS-EM iterative image reconstruction algorithms with the polygonal and conventional Cartesian pixel grid were developed. A hot rod phantom was detected and reconstructed based on these two grids with reasonable time cost. Image resolution of reconstructed images was both 1.35 mm. We conclude that it is feasible to reconstruct and display images in a polygonal image pixel structure based on a compressed system matrix in PET image reconstruction. (authors)

  16. Influence of OSEM and segmented attenuation correction in the calculation of standardised uptake values for [18F]FDG PET

    International Nuclear Information System (INIS)

    Visvikis, D.; Costa, D.C.; Bomanji, J.; Gacinovic, S.; Ell, P.J.; Cheze-LeRest, C.

    2001-01-01

    Standardised Uptake Values (SUVs) are widely used in positron emission tomography (PET) as a semi-quantitative index of fluorine-18 labelled fluorodeoxyglucose uptake. The objective of this study was to investigate any bias introduced in the calculation of SUVs as a result of employing ordered subsets-expectation maximisation (OSEM) image reconstruction and segmented attenuation correction (SAC). Variable emission and transmission time durations were investigated. Both a phantom and a clinical evaluation of the bias were carried out. The software implemented in the GE Advance PET scanner was used. Phantom studies simulating tumour imaging conditions were performed. Since a variable count rate may influence the results obtained using OSEM, similar acquisitions were performed at total count rates of 34 kcps and 12 kcps. Clinical data consisted of 100 patient studies. Emission datasets of 5 and 15 min duration were combined with 15-, 3-, 2- and 1-min transmission datasets for the reconstruction of both phantom and patient studies. Two SUVs were estimated using the average (SUV avg ) and the maximum (SUV max ) count density from regions of interest placed well inside structures of interest. The percentage bias of these SUVs compared with the values obtained using a reference image was calculated. The reference image was considered to be the one produced by filtered backprojection (FBP) image reconstruction with measured attenuation correction using the 15-min emission and transmission datasets for each phantom and patient study. A bias of 5%-20% was found for the SUV avg and SUV max in the case of FBP with SAC using variable transmission times. In the case of OSEM with SAC, the bias increased to 10%-30%. An overall increase of 5%-10% was observed with the use of SUV max . The 5-min emission dataset led to an increase in the bias of 25%-100%, with the larger increase recorded for the SUV max . The results suggest that OSEM and SAC with 3 and 2 min transmission may be

  17. Semiquantitative evaluation of "9"9mTctrodat1 binding potential by two methods of SPECT image reconstruction

    International Nuclear Information System (INIS)

    Leite, Melissa Furlaneto Lellis; Reis, Marilia Alves dos; Oliveira, Cassio Miri; Castiglioni, Mario Luiz Vieira; Bressan, Rodrigo Affonseca

    2017-01-01

    TRODAT-1 is a radiopharmaceutical derived from tropane and linked to Technetium-99m (["9"9"mTc] TRODAT-1) has been used in studies of dopamine transporter (DAT) in central nervous system. Associated with the SPECT technique of acquisition, is able to detect changes in neurological disorders like Parkinson´s disease, evaluating the binding potential (BP) of DAT. The aim of this study was to evaluate the influence of the image reconstruction methods, Filtered Back Projection (FBP) and iterative reconstruction (OSEM), in BP values at the striatal region in 30 healthy volunteers. Images were analyzed by visual inspection and semi-quantitative analysis. Regions of interest (ROI) were made over striatal areas on both sides. Nonparametric Wilcoxon statistical analysis was performed between the BP values from the FBP and OSEM methods. Our results showed that the reconstruction methods have a statistical significant BP values difference in the total striatum (Z = -2,2787 p = 0.005), right striatum (Z = -2,602 p = 0.009) and left striatum (Z= 2,746 p = 0.006). The effect size was calculated to see if there influence in this test: the 'large effect size' for all measurements was observed (total striatum r= -0.51; right striatum r= -0.48; left striatum r= -0.50). FBP is the usual method of reconstruction for brain SPECT images, and our results showed influence of the OSEM method in BP. It is concluded that the method of image reconstruction adopted should be standardized to avoid incorrect evaluations of BP values using ["9"9"mTc]TRODAT-1. (author)

  18. Semiquantitative evaluation of {sup 99}mTctrodat1 binding potential by two methods of SPECT image reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Leite, Melissa Furlaneto Lellis; Reis, Marilia Alves dos; Oliveira, Cassio Miri; Castiglioni, Mario Luiz Vieira; Bressan, Rodrigo Affonseca, E-mail: mefurlaneto@hotmail.com, E-mail: rodrigoabressan@gmail.com, E-mail: mario.castiglioni@uol.com.br [Universidade Federal de Sao Paulo (UNIFESP), SP (Brazil)

    2017-11-01

    TRODAT-1 is a radiopharmaceutical derived from tropane and linked to Technetium-99m ([{sup 99m}Tc] TRODAT-1) has been used in studies of dopamine transporter (DAT) in central nervous system. Associated with the SPECT technique of acquisition, is able to detect changes in neurological disorders like Parkinson´s disease, evaluating the binding potential (BP) of DAT. The aim of this study was to evaluate the influence of the image reconstruction methods, Filtered Back Projection (FBP) and iterative reconstruction (OSEM), in BP values at the striatal region in 30 healthy volunteers. Images were analyzed by visual inspection and semi-quantitative analysis. Regions of interest (ROI) were made over striatal areas on both sides. Nonparametric Wilcoxon statistical analysis was performed between the BP values from the FBP and OSEM methods. Our results showed that the reconstruction methods have a statistical significant BP values difference in the total striatum (Z = -2,2787 p = 0.005), right striatum (Z = -2,602 p = 0.009) and left striatum (Z= 2,746 p = 0.006). The effect size was calculated to see if there influence in this test: the 'large effect size' for all measurements was observed (total striatum r= -0.51; right striatum r= -0.48; left striatum r= -0.50). FBP is the usual method of reconstruction for brain SPECT images, and our results showed influence of the OSEM method in BP. It is concluded that the method of image reconstruction adopted should be standardized to avoid incorrect evaluations of BP values using [{sup 99m}Tc]TRODAT-1. (author)

  19. Efficient methodologies for system matrix modelling in iterative image reconstruction for rotating high-resolution PET

    Energy Technology Data Exchange (ETDEWEB)

    Ortuno, J E; Kontaxakis, G; Rubio, J L; Santos, A [Departamento de Ingenieria Electronica (DIE), Universidad Politecnica de Madrid, Ciudad Universitaria s/n, 28040 Madrid (Spain); Guerra, P [Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid (Spain)], E-mail: juanen@die.upm.es

    2010-04-07

    A fully 3D iterative image reconstruction algorithm has been developed for high-resolution PET cameras composed of pixelated scintillator crystal arrays and rotating planar detectors, based on the ordered subsets approach. The associated system matrix is precalculated with Monte Carlo methods that incorporate physical effects not included in analytical models, such as positron range effects and interaction of the incident gammas with the scintillator material. Custom Monte Carlo methodologies have been developed and optimized for modelling of system matrices for fast iterative image reconstruction adapted to specific scanner geometries, without redundant calculations. According to the methodology proposed here, only one-eighth of the voxels within two central transaxial slices need to be modelled in detail. The rest of the system matrix elements can be obtained with the aid of axial symmetries and redundancies, as well as in-plane symmetries within transaxial slices. Sparse matrix techniques for the non-zero system matrix elements are employed, allowing for fast execution of the image reconstruction process. This 3D image reconstruction scheme has been compared in terms of image quality to a 2D fast implementation of the OSEM algorithm combined with Fourier rebinning approaches. This work confirms the superiority of fully 3D OSEM in terms of spatial resolution, contrast recovery and noise reduction as compared to conventional 2D approaches based on rebinning schemes. At the same time it demonstrates that fully 3D methodologies can be efficiently applied to the image reconstruction problem for high-resolution rotational PET cameras by applying accurate pre-calculated system models and taking advantage of the system's symmetries.

  20. Evaluation of Origin Ensemble algorithm for image reconstruction for pixelated solid-state detectors with large number of channels

    Science.gov (United States)

    Kolstein, M.; De Lorenzo, G.; Mikhaylova, E.; Chmeissani, M.; Ariño, G.; Calderón, Y.; Ozsahin, I.; Uzun, D.

    2013-04-01

    The Voxel Imaging PET (VIP) Pathfinder project intends to show the advantages of using pixelated solid-state technology for nuclear medicine applications. It proposes designs for Positron Emission Tomography (PET), Positron Emission Mammography (PEM) and Compton gamma camera detectors with a large number of signal channels (of the order of 106). For PET scanners, conventional algorithms like Filtered Back-Projection (FBP) and Ordered Subset Expectation Maximization (OSEM) are straightforward to use and give good results. However, FBP presents difficulties for detectors with limited angular coverage like PEM and Compton gamma cameras, whereas OSEM has an impractically large time and memory consumption for a Compton gamma camera with a large number of channels. In this article, the Origin Ensemble (OE) algorithm is evaluated as an alternative algorithm for image reconstruction. Monte Carlo simulations of the PET design are used to compare the performance of OE, FBP and OSEM in terms of the bias, variance and average mean squared error (MSE) image quality metrics. For the PEM and Compton camera designs, results obtained with OE are presented.

  1. Optimization of image reconstruction method for SPECT studies performed using [⁹⁹mTc-EDDA/HYNIC] octreotate in patients with neuroendocrine tumors.

    Science.gov (United States)

    Sowa-Staszczak, Anna; Lenda-Tracz, Wioletta; Tomaszuk, Monika; Głowa, Bogusław; Hubalewska-Dydejczyk, Alicja

    2013-01-01

    Somatostatin receptor scintigraphy (SRS) is a useful tool in the assessment of GEP-NET (gastroenteropancreatic neuroendocrine tumor) patients. The choice of appropriate settings of image reconstruction parameters is crucial in interpretation of these images. The aim of the study was to investigate how the GEP NET lesion signal to noise ratio (TCS/TCB) depends on different reconstruction settings for Flash 3D software (Siemens). SRS results of 76 randomly selected patients with confirmed GEP-NET were analyzed. For SPECT studies the data were acquired using standard clinical settings 3-4 h after the injection of 740 MBq 99mTc-[EDDA/HYNIC] octreotate. To obtain final images the OSEM 3D Flash reconstruction with different settings and FBP reconstruction were used. First, the TCS/TCB ratio in voxels was analyzed for different combinations of the number of subsets and the number of iterations of the OSEM 3D Flash reconstruction. Secondly, the same ratio was analyzed for different parameters of the Gaussian filter (with FWHM = 2-4 times greater from the pixel size). Also the influence of scatter correction on the TCS/TCB ratio was investigated. With increasing number of subsets and iterations, the increase of TCS/TCB ratio was observed. With increasing settings of Gauss [FWHM coefficient] filter, the decrease of TCS/TCB ratio was reported. The use of scatter correction slightly decreases the values of this ratio. OSEM algorithm provides a meaningfully better reconstruction of the SRS SPECT study as compared to the FBP technique. A high number of subsets improves image quality (images are smoother). Increasing number of iterations gives a better contrast and the shapes of lesions and organs are sharper. The choice of reconstruction parameters is a compromise between image qualitative appearance and its quantitative accuracy and should not be modified when comparing multiple studies of the same patient.

  2. An implementation of the NiftyRec medical imaging library for PIXE-tomography reconstruction

    Science.gov (United States)

    Michelet, C.; Barberet, P.; Desbarats, P.; Giovannelli, J.-F.; Schou, C.; Chebil, I.; Delville, M.-H.; Gordillo, N.; Beasley, D. G.; Devès, G.; Moretto, P.; Seznec, H.

    2017-08-01

    A new development of the TomoRebuild software package is presented, including ;thick sample; correction for non linear X-ray production (NLXP) and X-ray absorption (XA). As in the previous versions, C++ programming with standard libraries was used for easier portability. Data reduction requires different steps which may be run either from a command line instruction or via a user friendly interface, developed as a portable Java plugin in ImageJ. All experimental and reconstruction parameters can be easily modified, either directly in the ASCII parameter files or via the ImageJ interface. A detailed user guide in English is provided. Sinograms and final reconstructed images are generated in usual binary formats that can be read by most public domain graphic softwares. New MLEM and OSEM methods are proposed, using optimized methods from the NiftyRec medical imaging library. An overview of the different medical imaging methods that have been used for ion beam microtomography applications is presented. In TomoRebuild, PIXET data reduction is performed for each chemical element independently and separately from STIMT, except for two steps where the fusion of STIMT and PIXET data is required: the calculation of the correction matrix and the normalization of PIXET data to obtain mass fraction distributions. Correction matrices for NLXP and XA are calculated using procedures extracted from the DISRA code, taking into account a large X-ray detection solid angle. For this, the 3D STIMT mass density distribution is used, considering a homogeneous global composition. A first example of PIXET experiment using two detectors is presented. Reconstruction results are compared and found in good agreement between different codes: FBP, NiftyRec MLEM and OSEM of the TomoRebuild software package, the original DISRA, its accelerated version provided in JPIXET and the accelerated MLEM version of JPIXET, with or without correction.

  3. Tomographic image reconstruction using training images

    DEFF Research Database (Denmark)

    Soltani, Sara; Andersen, Martin Skovgaard; Hansen, Per Christian

    2017-01-01

    We describe and examine an algorithm for tomographic image reconstruction where prior knowledge about the solution is available in the form of training images. We first construct a non-negative dictionary based on prototype elements from the training images; this problem is formulated within...

  4. MO-G-17A-07: Improved Image Quality in Brain F-18 FDG PET Using Penalized-Likelihood Image Reconstruction Via a Generalized Preconditioned Alternating Projection Algorithm: The First Patient Results

    Energy Technology Data Exchange (ETDEWEB)

    Schmidtlein, CR; Beattie, B; Humm, J [Memorial Sloan Kettering Cancer Center, New York, NY (United States); Li, S; Wu, Z; Xu, Y [Sun Yat-sen University, Guangzhou, Guangdong (China); Zhang, J; Shen, L [Syracuse University, Syracuse, NY (United States); Vogelsang, L [VirtualScopics, Rochester, NY (United States); Feiglin, D; Krol, A [SUNY Upstate Medical University, Syracuse, NY (United States)

    2014-06-15

    Purpose: To investigate the performance of a new penalized-likelihood PET image reconstruction algorithm using the 1{sub 1}-norm total-variation (TV) sum of the 1st through 4th-order gradients as the penalty. Simulated and brain patient data sets were analyzed. Methods: This work represents an extension of the preconditioned alternating projection algorithm (PAPA) for emission-computed tomography. In this new generalized algorithm (GPAPA), the penalty term is expanded to allow multiple components, in this case the sum of the 1st to 4th order gradients, to reduce artificial piece-wise constant regions (“staircase” artifacts typical for TV) seen in PAPA images penalized with only the 1st order gradient. Simulated data were used to test for “staircase” artifacts and to optimize the penalty hyper-parameter in the root-mean-squared error (RMSE) sense. Patient FDG brain scans were acquired on a GE D690 PET/CT (370 MBq at 1-hour post-injection for 10 minutes) in time-of-flight mode and in all cases were reconstructed using resolution recovery projectors. GPAPA images were compared PAPA and RMSE-optimally filtered OSEM (fully converged) in simulations and to clinical OSEM reconstructions (3 iterations, 32 subsets) with 2.6 mm XYGaussian and standard 3-point axial smoothing post-filters. Results: The results from the simulated data show a significant reduction in the 'staircase' artifact for GPAPA compared to PAPA and lower RMSE (up to 35%) compared to optimally filtered OSEM. A simple power-law relationship between the RMSE-optimal hyper-parameters and the noise equivalent counts (NEC) per voxel is revealed. Qualitatively, the patient images appear much sharper and with less noise than standard clinical images. The convergence rate is similar to OSEM. Conclusions: GPAPA reconstructions using the 1{sub 1}-norm total-variation sum of the 1st through 4th-order gradients as the penalty show great promise for the improvement of image quality over that

  5. MO-G-17A-07: Improved Image Quality in Brain F-18 FDG PET Using Penalized-Likelihood Image Reconstruction Via a Generalized Preconditioned Alternating Projection Algorithm: The First Patient Results

    International Nuclear Information System (INIS)

    Schmidtlein, CR; Beattie, B; Humm, J; Li, S; Wu, Z; Xu, Y; Zhang, J; Shen, L; Vogelsang, L; Feiglin, D; Krol, A

    2014-01-01

    Purpose: To investigate the performance of a new penalized-likelihood PET image reconstruction algorithm using the 1 1 -norm total-variation (TV) sum of the 1st through 4th-order gradients as the penalty. Simulated and brain patient data sets were analyzed. Methods: This work represents an extension of the preconditioned alternating projection algorithm (PAPA) for emission-computed tomography. In this new generalized algorithm (GPAPA), the penalty term is expanded to allow multiple components, in this case the sum of the 1st to 4th order gradients, to reduce artificial piece-wise constant regions (“staircase” artifacts typical for TV) seen in PAPA images penalized with only the 1st order gradient. Simulated data were used to test for “staircase” artifacts and to optimize the penalty hyper-parameter in the root-mean-squared error (RMSE) sense. Patient FDG brain scans were acquired on a GE D690 PET/CT (370 MBq at 1-hour post-injection for 10 minutes) in time-of-flight mode and in all cases were reconstructed using resolution recovery projectors. GPAPA images were compared PAPA and RMSE-optimally filtered OSEM (fully converged) in simulations and to clinical OSEM reconstructions (3 iterations, 32 subsets) with 2.6 mm XYGaussian and standard 3-point axial smoothing post-filters. Results: The results from the simulated data show a significant reduction in the 'staircase' artifact for GPAPA compared to PAPA and lower RMSE (up to 35%) compared to optimally filtered OSEM. A simple power-law relationship between the RMSE-optimal hyper-parameters and the noise equivalent counts (NEC) per voxel is revealed. Qualitatively, the patient images appear much sharper and with less noise than standard clinical images. The convergence rate is similar to OSEM. Conclusions: GPAPA reconstructions using the 1 1 -norm total-variation sum of the 1st through 4th-order gradients as the penalty show great promise for the improvement of image quality over that currently

  6. Dynamic PET image reconstruction integrating temporal regularization associated with respiratory motion correction for applications in oncology

    Science.gov (United States)

    Merlin, Thibaut; Visvikis, Dimitris; Fernandez, Philippe; Lamare, Frédéric

    2018-02-01

    Respiratory motion reduces both the qualitative and quantitative accuracy of PET images in oncology. This impact is more significant for quantitative applications based on kinetic modeling, where dynamic acquisitions are associated with limited statistics due to the necessity of enhanced temporal resolution. The aim of this study is to address these drawbacks, by combining a respiratory motion correction approach with temporal regularization in a unique reconstruction algorithm for dynamic PET imaging. Elastic transformation parameters for the motion correction are estimated from the non-attenuation-corrected PET images. The derived displacement matrices are subsequently used in a list-mode based OSEM reconstruction algorithm integrating a temporal regularization between the 3D dynamic PET frames, based on temporal basis functions. These functions are simultaneously estimated at each iteration, along with their relative coefficients for each image voxel. Quantitative evaluation has been performed using dynamic FDG PET/CT acquisitions of lung cancer patients acquired on a GE DRX system. The performance of the proposed method is compared with that of a standard multi-frame OSEM reconstruction algorithm. The proposed method achieved substantial improvements in terms of noise reduction while accounting for loss of contrast due to respiratory motion. Results on simulated data showed that the proposed 4D algorithms led to bias reduction values up to 40% in both tumor and blood regions for similar standard deviation levels, in comparison with a standard 3D reconstruction. Patlak parameter estimations on reconstructed images with the proposed reconstruction methods resulted in 30% and 40% bias reduction in the tumor and lung region respectively for the Patlak slope, and a 30% bias reduction for the intercept in the tumor region (a similar Patlak intercept was achieved in the lung area). Incorporation of the respiratory motion correction using an elastic model along with a

  7. Research on reconstruction of steel tube section from few projections

    International Nuclear Information System (INIS)

    Peng Shuaijun; Wu Haifeng; Wang Kai

    2007-01-01

    Most parameters of steel tube can be acquired from CT image of the section so as to evaluate its quality. But large numbers of projections are needed in order to reconstruct the section image, so the collection and calculation of the projections consume lots of time. In order to solve the problem, reconstruction algorithms of steel tube from few projections are researched and the results are validated with simulation data in the paper. Three iterative algorithms, ART, MAP and OSEM, are attempted to reconstruct the section of steel tube by using the simulation model. Considering the prior information distributing of steel tube, we improve the algorithms and get better reconstruction images. The results of simulation experiment indicate that ART, MAP and OSEM can reconstruct accurate section images of steel tube from less than 20 projections and approximate images from 10 projections. (authors)

  8. Statistical list-mode image reconstruction for the high resolution research tomograph

    International Nuclear Information System (INIS)

    Rahmim, A; Lenox, M; Reader, A J; Michel, C; Burbar, Z; Ruth, T J; Sossi, V

    2004-01-01

    We have investigated statistical list-mode reconstruction applicable to a depth-encoding high resolution research tomograph. An image non-negativity constraint has been employed in the reconstructions and is shown to effectively remove the overestimation bias introduced by the sinogram non-negativity constraint. We have furthermore implemented a convergent subsetized (CS) list-mode reconstruction algorithm, based on previous work (Hsiao et al 2002 Conf. Rec. SPIE Med. Imaging 4684 10-19; Hsiao et al 2002 Conf. Rec. IEEE Int. Symp. Biomed. Imaging 409-12) on convergent histogram OSEM reconstruction. We have demonstrated that the first step of the convergent algorithm is exactly equivalent (unlike the histogram-mode case) to the regular subsetized list-mode EM algorithm, while the second and final step takes the form of additive updates in image space. We have shown that in terms of contrast, noise as well as FWHM width behaviour, the CS algorithm is robust and does not result in limit cycles. A hybrid algorithm based on the ordinary and the convergent algorithms is also proposed, and is shown to combine the advantages of the two algorithms (i.e. it is able to reach a higher image quality in fewer iterations while maintaining the convergent behaviour), making the hybrid approach a good alternative to the ordinary subsetized list-mode EM algorithm

  9. Colour reconstruction of underwater images

    OpenAIRE

    Hoth, Julian; Kowalczyk, Wojciech

    2017-01-01

    Objects look very different in the underwater environment compared to their appearance in sunlight. Images with correct colouring simplify the detection of underwater objects and may allow the use of visual SLAM algorithms developed for land-based robots underwater. Hence, image processing is required. Current algorithms focus on the colour reconstruction of scenery at diving depth where different colours can still be distinguished. At greater depth this is not the case. In this study it is i...

  10. DG TOMO: A new method for tomographic reconstruction

    International Nuclear Information System (INIS)

    Freitas, D. de; Feschet, F.; Cachin, F.; Geissler, B.; Bapt, A.; Karidioula, I.; Martin, C.; Kelly, A.; Mestas, D.; Gerard, Y.; Reveilles, J.P.; Maublant, J.

    2006-01-01

    Aim: FBP and OSEM are the most popular tomographic reconstruction methods in scintigraphy. FBP is a simple method but artifacts of reconstruction are generated which corrections induce degradation of the spatial resolution. OSEM takes account of statistical fluctuations but noise strongly increases after a certain number of iterations. We compare a new method of tomographic reconstruction based on discrete geometry (DG TOMO) to FBP and OSEM. Materials and methods: Acquisitions were performed on a three-head gamma-camera (Philips) with a NEMA Phantom containing six spheres of sizes from 10 to 37 mm inner diameter, filled with around 325 MBq/l of technetium-99 m. The spheres were positioned in water containing 3 MBq/l of technetium-99 m. Acquisitions were realized during a 180 o -rotation around the phantom by 25-s steps. DG TOMO has been developed in our laboratory in order to minimize the number of projections at acquisition. Two tomographic reconstructions utilizing 32 and 16 projections with FBP, OSEM and DG TOMO were performed and transverse slices were compared. Results: FBP with 32 projections detects only the activity in the three largest spheres (diameter ≥22 mm). With 16 projections, the star effect is predominant and the contrast of the third sphere is very low. OSEM with 32 projections provides a better image but the three smallest spheres (diameter ≤17 mm) are difficult to distinguish. With 16 projections, the three smaller spheres are not detectable. The results of DG TOMO are similar to OSEM. Conclusion: Since the parameters of DG TOMO can be further optimized, this method appears as a promising alternative for tomoscintigraphy reconstruction

  11. Accelerated time-of-flight (TOF) PET image reconstruction using TOF bin subsetization and TOF weighting matrix pre-computation

    International Nuclear Information System (INIS)

    Mehranian, Abolfazl; Kotasidis, Fotis; Zaidi, Habib

    2016-01-01

    Time-of-flight (TOF) positron emission tomography (PET) technology has recently regained popularity in clinical PET studies for improving image quality and lesion detectability. Using TOF information, the spatial location of annihilation events is confined to a number of image voxels along each line of response, thereby the cross-dependencies of image voxels are reduced, which in turns results in improved signal-to-noise ratio and convergence rate. In this work, we propose a novel approach to further improve the convergence of the expectation maximization (EM)-based TOF PET image reconstruction algorithm through subsetization of emission data over TOF bins as well as azimuthal bins. Given the prevalence of TOF PET, we elaborated the practical and efficient implementation of TOF PET image reconstruction through the pre-computation of TOF weighting coefficients while exploiting the same in-plane and axial symmetries used in pre-computation of geometric system matrix. In the proposed subsetization approach, TOF PET data were partitioned into a number of interleaved TOF subsets, with the aim of reducing the spatial coupling of TOF bins and therefore to improve the convergence of the standard maximum likelihood expectation maximization (MLEM) and ordered subsets EM (OSEM) algorithms. The comparison of on-the-fly and pre-computed TOF projections showed that the pre-computation of the TOF weighting coefficients can considerably reduce the computation time of TOF PET image reconstruction. The convergence rate and bias-variance performance of the proposed TOF subsetization scheme were evaluated using simulated, experimental phantom and clinical studies. Simulations demonstrated that as the number of TOF subsets is increased, the convergence rate of MLEM and OSEM algorithms is improved. It was also found that for the same computation time, the proposed subsetization gives rise to further convergence. The bias-variance analysis of the experimental NEMA phantom and a clinical

  12. Evaluation of penalized likelihood estimation reconstruction on a digital time-of-flight PET/CT scanner for 18F-FDG whole-body examinations.

    Science.gov (United States)

    Lindström, Elin; Sundin, Anders; Trampal, Carlos; Lindsjö, Lars; Ilan, Ezgi; Danfors, Torsten; Antoni, Gunnar; Sörensen, Jens; Lubberink, Mark

    2018-02-15

    Resolution and quantitative accuracy of positron emission tomography (PET) are highly influenced by the reconstruction method. Penalized likelihood estimation algorithms allow for fully convergent iterative reconstruction, generating a higher image contrast while limiting noise compared to ordered subsets expectation maximization (OSEM). In this study, block-sequential regularized expectation maximization (BSREM) was compared to time-of-flight OSEM (TOF-OSEM). Various strengths of noise penalization factor β were tested along with scan durations and transaxial field of views (FOVs) with the aim to evaluate the performance and clinical use of BSREM for 18 F-FDG-PET-computed tomography (CT), both in quantitative terms and in a qualitative visual evaluation. Methods: Eleven clinical whole-body 18 F-FDG-PET/CT examinations acquired on a digital TOF PET/CT scanner were included. The data were reconstructed using BSREM with point spread function (PSF) recovery and β 133, 267, 400 and 533, and TOF-OSEM with PSF, for various acquisition times/bed position (bp) and FOVs. Noise, signal-to-noise ratio (SNR), signal-to-background ratio (SBR), and standardized uptake values (SUVs) were analysed. A blinded visual image quality evaluation, rating several aspects, performed by two nuclear medicine physicians complemented the analysis. Results: The lowest levels of noise were reached with the highest β resulting in the highest SNR, which in turn resulted in the lowest SBR. Noise equivalence to TOF-OSEM was found with β 400 but produced a significant increase of SUV max (11%), SNR (22%) and SBR (12%) compared to TOF-OSEM. BSREM with β 533 at decreased acquisition (2 min/bp) was comparable to TOF-OSEM at full acquisition duration (3 min/bp). Reconstructed FOV had an impact on BSREM outcome measures, SNR increased while SBR decreased when shifting FOV from 70 to 50 cm. The visual image quality evaluation resulted in similar scores for reconstructions although β 400 obtained the

  13. Method for position emission mammography image reconstruction

    Science.gov (United States)

    Smith, Mark Frederick

    2004-10-12

    An image reconstruction method comprising accepting coincidence datat from either a data file or in real time from a pair of detector heads, culling event data that is outside a desired energy range, optionally saving the desired data for each detector position or for each pair of detector pixels on the two detector heads, and then reconstructing the image either by backprojection image reconstruction or by iterative image reconstruction. In the backprojection image reconstruction mode, rays are traced between centers of lines of response (LOR's), counts are then either allocated by nearest pixel interpolation or allocated by an overlap method and then corrected for geometric effects and attenuation and the data file updated. If the iterative image reconstruction option is selected, one implementation is to compute a grid Siddon retracing, and to perform maximum likelihood expectation maiximization (MLEM) computed by either: a) tracing parallel rays between subpixels on opposite detector heads; or b) tracing rays between randomized endpoint locations on opposite detector heads.

  14. Evaluation of list-mode ordered subset expectation maximization image reconstruction for pixelated solid-state compton gamma camera with large number of channels

    Science.gov (United States)

    Kolstein, M.; De Lorenzo, G.; Chmeissani, M.

    2014-04-01

    The Voxel Imaging PET (VIP) Pathfinder project intends to show the advantages of using pixelated solid-state technology for nuclear medicine applications. It proposes designs for Positron Emission Tomography (PET), Positron Emission Mammography (PEM) and Compton gamma camera detectors with a large number of signal channels (of the order of 106). For Compton camera, especially with a large number of readout channels, image reconstruction presents a big challenge. In this work, results are presented for the List-Mode Ordered Subset Expectation Maximization (LM-OSEM) image reconstruction algorithm on simulated data with the VIP Compton camera design. For the simulation, all realistic contributions to the spatial resolution are taken into account, including the Doppler broadening effect. The results show that even with a straightforward implementation of LM-OSEM, good images can be obtained for the proposed Compton camera design. Results are shown for various phantoms, including extended sources and with a distance between the field of view and the first detector plane equal to 100 mm which corresponds to a realistic nuclear medicine environment.

  15. Tomographic image reconstruction using Artificial Neural Networks

    International Nuclear Information System (INIS)

    Paschalis, P.; Giokaris, N.D.; Karabarbounis, A.; Loudos, G.K.; Maintas, D.; Papanicolas, C.N.; Spanoudaki, V.; Tsoumpas, Ch.; Stiliaris, E.

    2004-01-01

    A new image reconstruction technique based on the usage of an Artificial Neural Network (ANN) is presented. The most crucial factor in designing such a reconstruction system is the network architecture and the number of the input projections needed to reconstruct the image. Although the training phase requires a large amount of input samples and a considerable CPU time, the trained network is characterized by simplicity and quick response. The performance of this ANN is tested using several image patterns. It is intended to be used together with a phantom rotating table and the γ-camera of IASA for SPECT image reconstruction

  16. Optoelectronic Computer Architecture Development for Image Reconstruction

    National Research Council Canada - National Science Library

    Forber, Richard

    1996-01-01

    .... Specifically, we collaborated with UCSD and ERIM on the development of an optically augmented electronic computer for high speed inverse transform calculations to enable real time image reconstruction...

  17. EIT image reconstruction with four dimensional regularization.

    Science.gov (United States)

    Dai, Tao; Soleimani, Manuchehr; Adler, Andy

    2008-09-01

    Electrical impedance tomography (EIT) reconstructs internal impedance images of the body from electrical measurements on body surface. The temporal resolution of EIT data can be very high, although the spatial resolution of the images is relatively low. Most EIT reconstruction algorithms calculate images from data frames independently, although data are actually highly correlated especially in high speed EIT systems. This paper proposes a 4-D EIT image reconstruction for functional EIT. The new approach is developed to directly use prior models of the temporal correlations among images and 3-D spatial correlations among image elements. A fast algorithm is also developed to reconstruct the regularized images. Image reconstruction is posed in terms of an augmented image and measurement vector which are concatenated from a specific number of previous and future frames. The reconstruction is then based on an augmented regularization matrix which reflects the a priori constraints on temporal and 3-D spatial correlations of image elements. A temporal factor reflecting the relative strength of the image correlation is objectively calculated from measurement data. Results show that image reconstruction models which account for inter-element correlations, in both space and time, show improved resolution and noise performance, in comparison to simpler image models.

  18. Application of the OS-EM method to the 123I-IMP ARG method. Comparison between FBP and OS-EM methods

    International Nuclear Information System (INIS)

    Sasaki, Kazuko; Satou, Ayuko; Oomura, Tomomi; Ono, Madoka; Hachiya, Takenori

    2004-01-01

    We investigated application of the ordered subsets-expectation maximization (OS-EM) method to the 123 I-IMP autoradiography (ARG) method to measure regional cerebral blood flow (rCBF). First, scan time and subsets were fixed at 20 min and 16, respectively, and the influence of iteration on the cross calibration factor (CCF) and quantitative rCBF values obtained by the ARG method was investigated when the iteration number was set at 2, 4, 8, 16, 32, and 90. Next, with the number of iterations set at 4, we compared the scanning times of OS-EM and filtered back projection (FBP). We determined that the CCF values remained at the same level irrespective of iteration number. Quantitative rCBF values had no association with iteration number, either. Using the quantitative rCBF values obtained by 20-min. scanning with FBP as a standard, the time period for collecting SPECT data was 10 min, without sacrificing image quality or quantification. Quantitative rCBF obtained by OS-EM was estimated to be higher than that by FBP. (author)

  19. High-speed reconstruction of compressed images

    Science.gov (United States)

    Cox, Jerome R., Jr.; Moore, Stephen M.

    1990-07-01

    A compression scheme is described that allows high-definition radiological images with greater than 8-bit intensity resolution to be represented by 8-bit pixels. Reconstruction of the images with their original intensity resolution can be carried out by means of a pipeline architecture suitable for compact, high-speed implementation. A reconstruction system is described that can be fabricated according to this approach and placed between an 8-bit display buffer and the display's video system thereby allowing contrast control of images at video rates. Results for 50 CR chest images are described showing that error-free reconstruction of the original 10-bit CR images can be achieved.

  20. Iterative image reconstruction in ECT

    International Nuclear Information System (INIS)

    Chintu Chen; Ordonez, C.E.; Wernick, M.N.; Aarsvold, J.N.; Gunter, D.L.; Wong, W.H.; Kapp, O.H.; Xiaolong Ouyang; Levenson, M.; Metz, C.E.

    1992-01-01

    A series of preliminary studies has been performed in the authors laboratories to explore the use of a priori information in Bayesian image restoration and reconstruction. One piece of a priori information is the fact that intensities of neighboring pixels tend to be similar if they belong to the same region within which similar tissue characteristics are exhibited. this property of local continuity can be modeled by the use of Gibbs priors, as first suggested by German and Geman. In their investigation, they also included line sites between each pair of neighboring pixels in the Gibbs prior and used discrete binary numbers to indicate the absence or presence of boundaries between regions. These two features of the a priori model permit averaging within boundaries of homogeneous regions to alleviate the degradation caused by Poisson noise. with the use of this Gibbs prior in combination with the technique of stochastic relaxation, German and Geman demonstrated that noise levels can be reduced significantly in 2-D image restoration. They have developed a Bayesian method that utilizes a Gibbs prior to describe the spatial correlation of neighboring regions and takes into account the effect of limited spatial resolution as well. The statistical framework of the proposed approach is based on the data augmentation scheme suggested by Tanner and Wong. Briefly outlined here, this Bayesian method is based on Geman and Geman's approach

  1. Sparse Image Reconstruction in Computed Tomography

    DEFF Research Database (Denmark)

    Jørgensen, Jakob Sauer

    In recent years, increased focus on the potentially harmful effects of x-ray computed tomography (CT) scans, such as radiation-induced cancer, has motivated research on new low-dose imaging techniques. Sparse image reconstruction methods, as studied for instance in the field of compressed sensing...... applications. This thesis takes a systematic approach toward establishing quantitative understanding of conditions for sparse reconstruction to work well in CT. A general framework for analyzing sparse reconstruction methods in CT is introduced and two sets of computational tools are proposed: 1...... contributions to a general set of computational characterization tools. Thus, the thesis contributions help advance sparse reconstruction methods toward routine use in...

  2. Reconstruction of Undersampled Atomic Force Microscopy Images

    DEFF Research Database (Denmark)

    Jensen, Tobias Lindstrøm; Arildsen, Thomas; Østergaard, Jan

    2013-01-01

    Atomic force microscopy (AFM) is one of the most advanced tools for high-resolution imaging and manipulation of nanoscale matter. Unfortunately, standard AFM imaging requires a timescale on the order of seconds to minutes to acquire an image which makes it complicated to observe dynamic processes....... Moreover, it is often required to take several images before a relevant observation region is identified. In this paper we show how to significantly reduce the image acquisition time by undersampling. The reconstruction of an undersampled AFM image can be viewed as an inpainting, interpolating problem...... should be reconstructed using interpolation....

  3. SU-E-J-100: Reconstruction of Prompt Gamma Ray Three Dimensional SPECT Image From Boron Neutron Capture Therapy(BNCT)

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, D; Jung, J; Suh, T [The Catholic University of Korea, College of medicine, Department of biomedical engineering (Korea, Republic of)

    2014-06-01

    Purpose: Purpose of paper is to confirm the feasibility of acquisition of three dimensional single photon emission computed tomography (SPECT) image from boron neutron capture therapy (BNCT) using Monte Carlo simulation. Methods: In case of simulation, the pixelated SPECT detector, collimator and phantom were simulated using Monte Carlo n particle extended (MCNPX) simulation tool. A thermal neutron source (<1 eV) was used to react with the boron uptake region (BUR) in the phantom. Each geometry had a spherical pattern, and three different BURs (A, B and C region, density: 2.08 g/cm3) were located in the middle of the brain phantom. The data from 128 projections for each sorting process were used to achieve image reconstruction. The ordered subset expectation maximization (OSEM) reconstruction algorithm was used to obtain a tomographic image with eight subsets and five iterations. The receiver operating characteristic (ROC) curve analysis was used to evaluate the geometric accuracy of reconstructed image. Results: The OSEM image was compared with the original phantom pattern image. The area under the curve (AUC) was calculated as the gross area under each ROC curve. The three calculated AUC values were 0.738 (A region), 0.623 (B region), and 0.817 (C region). The differences between length of centers of two boron regions and distance of maximum count points were 0.3 cm, 1.6 cm and 1.4 cm. Conclusion: The possibility of extracting a 3D BNCT SPECT image was confirmed using the Monte Carlo simulation and OSEM algorithm. The prospects for obtaining an actual BNCT SPECT image were estimated from the quality of the simulated image and the simulation conditions. When multiple tumor region should be treated using the BNCT, a reasonable model to determine how many useful images can be obtained from the SPECT could be provided to the BNCT facilities. This research was supported by the Leading Foreign Research Institute Recruitment Program through the National Research

  4. Medical image reconstruction. A conceptual tutorial

    International Nuclear Information System (INIS)

    Zeng, Gengsheng Lawrence

    2010-01-01

    ''Medical Image Reconstruction: A Conceptual Tutorial'' introduces the classical and modern image reconstruction technologies, such as two-dimensional (2D) parallel-beam and fan-beam imaging, three-dimensional (3D) parallel ray, parallel plane, and cone-beam imaging. This book presents both analytical and iterative methods of these technologies and their applications in X-ray CT (computed tomography), SPECT (single photon emission computed tomography), PET (positron emission tomography), and MRI (magnetic resonance imaging). Contemporary research results in exact region-of-interest (ROI) reconstruction with truncated projections, Katsevich's cone-beam filtered backprojection algorithm, and reconstruction with highly undersampled data with l 0 -minimization are also included. (orig.)

  5. Algorithms for reconstructing images for industrial applications

    International Nuclear Information System (INIS)

    Lopes, R.T.; Crispim, V.R.

    1986-01-01

    Several algorithms for reconstructing objects from their projections are being studied in our Laboratory, for industrial applications. Such algorithms are useful locating the position and shape of different composition of materials in the object. A Comparative study of two algorithms is made. The two investigated algorithsm are: The MART (Multiplicative - Algebraic Reconstruction Technique) and the Convolution Method. The comparison are carried out from the point view of the quality of the image reconstructed, number of views and cost. (Author) [pt

  6. Parallel Algorithm for Reconstruction of TAC Images

    International Nuclear Information System (INIS)

    Vidal Gimeno, V.

    2012-01-01

    The algebraic reconstruction methods are based on solving a system of linear equations. In a previous study, was used and showed as the PETSc library, was and is a scientific computing tool, which facilitates and enables the optimal use of a computer system in the image reconstruction process.

  7. Speeding up image reconstruction in computed tomography

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    Computed tomography (CT) is a technique for imaging cross-sections of an object using X-ray measurements taken from different angles. In last decades a significant progress has happened there: today advanced algorithms allow fast image reconstruction and obtaining high-quality images even with missing or dirty data, modern detectors provide high resolution without increasing radiation dose, and high-performance multi-core computing devices are there to help us solving such tasks even faster. I will start with CT basics, then briefly present existing classes of reconstruction algorithms and their differences. After that I will proceed to employing distinctive architectural features of modern multi-core devices (CPUs and GPUs) and popular program interfaces (OpenMP, MPI, CUDA, OpenCL) for developing effective parallel realizations of image reconstruction algorithms. Decreasing full reconstruction time from long hours up to minutes or even seconds has a revolutionary impact in diagnostic medicine and industria...

  8. Parallel CT image reconstruction based on GPUs

    International Nuclear Information System (INIS)

    Flores, Liubov A.; Vidal, Vicent; Mayo, Patricia; Rodenas, Francisco; Verdú, Gumersindo

    2014-01-01

    In X-ray computed tomography (CT) iterative methods are more suitable for the reconstruction of images with high contrast and precision in noisy conditions from a small number of projections. However, in practice, these methods are not widely used due to the high computational cost of their implementation. Nowadays technology provides the possibility to reduce effectively this drawback. It is the goal of this work to develop a fast GPU-based algorithm to reconstruct high quality images from under sampled and noisy projection data. - Highlights: • We developed GPU-based iterative algorithm to reconstruct images. • Iterative algorithms are capable to reconstruct images from under sampled set of projections. • The computer cost of the implementation of the developed algorithm is low. • The efficiency of the algorithm increases for the large scale problems

  9. Reconstruction Algorithms in Undersampled AFM Imaging

    DEFF Research Database (Denmark)

    Arildsen, Thomas; Oxvig, Christian Schou; Pedersen, Patrick Steffen

    2016-01-01

    This paper provides a study of spatial undersampling in atomic force microscopy (AFM) imaging followed by different image reconstruction techniques based on sparse approximation as well as interpolation. The main reasons for using undersampling is that it reduces the path length and thereby...... the scanning time as well as the amount of interaction between the AFM probe and the specimen. It can easily be applied on conventional AFM hardware. Due to undersampling, it is then necessary to further process the acquired image in order to reconstruct an approximation of the image. Based on real AFM cell...... images, our simulations reveal that using a simple raster scanning pattern in combination with conventional image interpolation performs very well. Moreover, this combination enables a reduction by a factor 10 of the scanning time while retaining an average reconstruction quality around 36 dB PSNR...

  10. 3D Reconstruction of NMR Images

    Directory of Open Access Journals (Sweden)

    Peter Izak

    2007-01-01

    Full Text Available This paper introduces experiment of 3D reconstruction NMR images scanned from magnetic resonance device. There are described methods which can be used for 3D reconstruction magnetic resonance images in biomedical application. The main idea is based on marching cubes algorithm. For this task was chosen sophistication method by program Vision Assistant, which is a part of program LabVIEW.

  11. Evaluation of 3D reconstruction algorithms for a small animal PET camera

    International Nuclear Information System (INIS)

    Johnson, C.A.; Gandler, W.R.; Seidel, J.

    1996-01-01

    The use of paired, opposing position-sensitive phototube scintillation cameras (SCs) operating in coincidence for small animal imaging with positron emitters is currently under study. Because of the low sensitivity of the system even in 3D mode and the need to produce images with high resolution, it was postulated that a 3D expectation maximization (EM) reconstruction algorithm might be well suited for this application. We investigated four reconstruction algorithms for the 3D SC PET camera: 2D filtered back-projection (FBP), 2D ordered subset EM (OSEM), 3D reprojection (3DRP), and 3D OSEM. Noise was assessed for all slices by the coefficient of variation in a simulated uniform cylinder. Resolution was assessed from a simulation of 15 point sources in the warm background of the uniform cylinder. At comparable noise levels, the resolution achieved with OSEM (0.9-mm to 1.2-mm) is significantly better than that obtained with FBP or 3DRP (1.5-mm to 2.0-mm.) Images of a rat skull labeled with 18 F-fluoride suggest that 3D OSEM can improve image quality of a small animal PET camera

  12. Fast parallel algorithm for CT image reconstruction.

    Science.gov (United States)

    Flores, Liubov A; Vidal, Vicent; Mayo, Patricia; Rodenas, Francisco; Verdú, Gumersindo

    2012-01-01

    In X-ray computed tomography (CT) the X rays are used to obtain the projection data needed to generate an image of the inside of an object. The image can be generated with different techniques. Iterative methods are more suitable for the reconstruction of images with high contrast and precision in noisy conditions and from a small number of projections. Their use may be important in portable scanners for their functionality in emergency situations. However, in practice, these methods are not widely used due to the high computational cost of their implementation. In this work we analyze iterative parallel image reconstruction with the Portable Extensive Toolkit for Scientific computation (PETSc).

  13. Photoacoustic image reconstruction via deep learning

    Science.gov (United States)

    Antholzer, Stephan; Haltmeier, Markus; Nuster, Robert; Schwab, Johannes

    2018-02-01

    Applying standard algorithms to sparse data problems in photoacoustic tomography (PAT) yields low-quality images containing severe under-sampling artifacts. To some extent, these artifacts can be reduced by iterative image reconstruction algorithms which allow to include prior knowledge such as smoothness, total variation (TV) or sparsity constraints. These algorithms tend to be time consuming as the forward and adjoint problems have to be solved repeatedly. Further, iterative algorithms have additional drawbacks. For example, the reconstruction quality strongly depends on a-priori model assumptions about the objects to be recovered, which are often not strictly satisfied in practical applications. To overcome these issues, in this paper, we develop direct and efficient reconstruction algorithms based on deep learning. As opposed to iterative algorithms, we apply a convolutional neural network, whose parameters are trained before the reconstruction process based on a set of training data. For actual image reconstruction, a single evaluation of the trained network yields the desired result. Our presented numerical results (using two different network architectures) demonstrate that the proposed deep learning approach reconstructs images with a quality comparable to state of the art iterative reconstruction methods.

  14. Evaluating low pass filters on SPECT reconstructed cardiac orientation estimation

    Science.gov (United States)

    Dwivedi, Shekhar

    2009-02-01

    Low pass filters can affect the quality of clinical SPECT images by smoothing. Appropriate filter and parameter selection leads to optimum smoothing that leads to a better quantification followed by correct diagnosis and accurate interpretation by the physician. This study aims at evaluating the low pass filters on SPECT reconstruction algorithms. Criteria for evaluating the filters are estimating the SPECT reconstructed cardiac azimuth and elevation angle. Low pass filters studied are butterworth, gaussian, hamming, hanning and parzen. Experiments are conducted using three reconstruction algorithms, FBP (filtered back projection), MLEM (maximum likelihood expectation maximization) and OSEM (ordered subsets expectation maximization), on four gated cardiac patient projections (two patients with stress and rest projections). Each filter is applied with varying cutoff and order for each reconstruction algorithm (only butterworth used for MLEM and OSEM). The azimuth and elevation angles are calculated from the reconstructed volume and the variation observed in the angles with varying filter parameters is reported. Our results demonstrate that behavior of hamming, hanning and parzen filter (used with FBP) with varying cutoff is similar for all the datasets. Butterworth filter (cutoff > 0.4) behaves in a similar fashion for all the datasets using all the algorithms whereas with OSEM for a cutoff < 0.4, it fails to generate cardiac orientation due to oversmoothing, and gives an unstable response with FBP and MLEM. This study on evaluating effect of low pass filter cutoff and order on cardiac orientation using three different reconstruction algorithms provides an interesting insight into optimal selection of filter parameters.

  15. MR image reconstruction via guided filter.

    Science.gov (United States)

    Huang, Heyan; Yang, Hang; Wang, Kang

    2018-04-01

    Magnetic resonance imaging (MRI) reconstruction from the smallest possible set of Fourier samples has been a difficult problem in medical imaging field. In our paper, we present a new approach based on a guided filter for efficient MRI recovery algorithm. The guided filter is an edge-preserving smoothing operator and has better behaviors near edges than the bilateral filter. Our reconstruction method is consist of two steps. First, we propose two cost functions which could be computed efficiently and thus obtain two different images. Second, the guided filter is used with these two obtained images for efficient edge-preserving filtering, and one image is used as the guidance image, the other one is used as a filtered image in the guided filter. In our reconstruction algorithm, we can obtain more details by introducing guided filter. We compare our reconstruction algorithm with some competitive MRI reconstruction techniques in terms of PSNR and visual quality. Simulation results are given to show the performance of our new method.

  16. Photoacoustic image reconstruction: a quantitative analysis

    Science.gov (United States)

    Sperl, Jonathan I.; Zell, Karin; Menzenbach, Peter; Haisch, Christoph; Ketzer, Stephan; Marquart, Markus; Koenig, Hartmut; Vogel, Mika W.

    2007-07-01

    Photoacoustic imaging is a promising new way to generate unprecedented contrast in ultrasound diagnostic imaging. It differs from other medical imaging approaches, in that it provides spatially resolved information about optical absorption of targeted tissue structures. Because the data acquisition process deviates from standard clinical ultrasound, choice of the proper image reconstruction method is crucial for successful application of the technique. In the literature, multiple approaches have been advocated, and the purpose of this paper is to compare four reconstruction techniques. Thereby, we focused on resolution limits, stability, reconstruction speed, and SNR. We generated experimental and simulated data and reconstructed images of the pressure distribution using four different methods: delay-and-sum (DnS), circular backprojection (CBP), generalized 2D Hough transform (HTA), and Fourier transform (FTA). All methods were able to depict the point sources properly. DnS and CBP produce blurred images containing typical superposition artifacts. The HTA provides excellent SNR and allows a good point source separation. The FTA is the fastest and shows the best FWHM. In our study, we found the FTA to show the best overall performance. It allows a very fast and theoretically exact reconstruction. Only a hardware-implemented DnS might be faster and enable real-time imaging. A commercial system may also perform several methods to fully utilize the new contrast mechanism and guarantee optimal resolution and fidelity.

  17. Heuristic optimization in penumbral image for high resolution reconstructed image

    International Nuclear Information System (INIS)

    Azuma, R.; Nozaki, S.; Fujioka, S.; Chen, Y. W.; Namihira, Y.

    2010-01-01

    Penumbral imaging is a technique which uses the fact that spatial information can be recovered from the shadow or penumbra that an unknown source casts through a simple large circular aperture. The size of the penumbral image on the detector can be mathematically determined as its aperture size, object size, and magnification. Conventional reconstruction methods are very sensitive to noise. On the other hand, the heuristic reconstruction method is very tolerant of noise. However, the aperture size influences the accuracy and resolution of the reconstructed image. In this article, we propose the optimization of the aperture size for the neutron penumbral imaging.

  18. Computational acceleration for MR image reconstruction in partially parallel imaging.

    Science.gov (United States)

    Ye, Xiaojing; Chen, Yunmei; Huang, Feng

    2011-05-01

    In this paper, we present a fast numerical algorithm for solving total variation and l(1) (TVL1) based image reconstruction with application in partially parallel magnetic resonance imaging. Our algorithm uses variable splitting method to reduce computational cost. Moreover, the Barzilai-Borwein step size selection method is adopted in our algorithm for much faster convergence. Experimental results on clinical partially parallel imaging data demonstrate that the proposed algorithm requires much fewer iterations and/or less computational cost than recently developed operator splitting and Bregman operator splitting methods, which can deal with a general sensing matrix in reconstruction framework, to get similar or even better quality of reconstructed images.

  19. 3-D image reconstruction in radiology

    International Nuclear Information System (INIS)

    Grangeat, P.

    1999-01-01

    In this course, we present highlights on fully 3-D image reconstruction algorithms used in 3-D X-ray Computed Tomography (3-D-CT) and 3-D Rotational Radiography (3-D-RR). We first consider the case of spiral CT with a one-row detector. Starting from the 2-D fan-beam inversion formula for a circular trajectory, we introduce spiral CT 3-D image reconstruction algorithm using axial interpolation for each transverse slice. In order to improve the X-ray detection efficiency and to speed the acquisition process, the future is to use multi-row detectors associated with small angle cone-beam geometry. The generalization of the 2-D fan-beam image reconstruction algorithm to cone beam defined direct inversion formula referred as Feldkamp's algorithm for a circular trajectory and Wang's algorithm for a spiral trajectory. However, large area detectors does exist such as Radiological Image Intensifiers or in a near future solid state detectors. To get a larger zoom effect, it defines a cone-beam geometry associated with a large aperture angle. For this case, we introduce indirect image reconstruction algorithm by plane re-binning in the Radon domain. We will present some results from a prototype MORPHOMETER device using the RADON reconstruction software. Lastly, we consider the special case of 3-D Rotational Digital Subtraction Angiography with a restricted number of views. We introduce constraint optimization algorithm using quadratic, entropic or half-quadratic constraints. Generalized ART (Algebraic Reconstruction Technique) iterative reconstruction algorithm can be derived from the Bregman algorithm. We present reconstructed vascular trees from a prototype MORPHOMETER device. (author)

  20. A combinational fast algorithm for image reconstruction

    International Nuclear Information System (INIS)

    Wu Zhongquan

    1987-01-01

    A combinational fast algorithm has been developed in order to increase the speed of reconstruction. First, an interpolation method based on B-spline functions is used in image reconstruction. Next, the influence of the boundary conditions assumed here on the interpolation of filtered projections and on the image reconstruction is discussed. It is shown that this boundary condition has almost no influence on the image in the central region of the image space, because the error of interpolation rapidly decreases by a factor of ten in shifting two pixels from the edge toward the center. In addition, a fast algorithm for computing the detecting angle has been used with the mentioned interpolation algorithm, and the cost for detecting angle computaton is reduced by a factor of two. The implementation results show that in the same subjective and objective fidelity, the computational cost for the interpolation using this algorithm is about one-twelfth of the conventional algorithm

  1. Improvement of brain perfusion SPET using iterative reconstruction with scatter and non-uniform attenuation correction

    Energy Technology Data Exchange (ETDEWEB)

    Kauppinen, T.; Vanninen, E.; Kuikka, J.T. [Kuopio Central Hospital (Finland). Dept. of Clinical Physiology; Koskinen, M.O. [Dept. of Clinical Physiology and Nuclear Medicine, Tampere Univ. Hospital, Tampere (Finland); Alenius, S. [Signal Processing Lab., Tampere Univ. of Technology, Tampere (Finland)

    2000-09-01

    Filtered back-projection (FBP) is generally used as the reconstruction method for single-photon emission tomography although it produces noisy images with apparent streak artefacts. It is possible to improve the image quality by using an algorithm with iterative correction steps. The iterative reconstruction technique also has an additional benefit in that computation of attenuation correction can be included in the process. A commonly used iterative method, maximum-likelihood expectation maximisation (ML-EM), can be accelerated using ordered subsets (OS-EM). We have applied to the OS-EM algorithm a Bayesian one-step late correction method utilising median root prior (MRP). Methodological comparison was performed by means of measurements obtained with a brain perfusion phantom and using patient data. The aim of this work was to quantitate the accuracy of iterative reconstruction with scatter and non-uniform attenuation corrections and post-filtering in SPET brain perfusion imaging. SPET imaging was performed using a triple-head gamma camera with fan-beam collimators. Transmission and emission scans were acquired simultaneously. The brain phantom used was a high-resolution three-dimensional anthropomorphic JB003 phantom. Patient studies were performed in ten chronic pain syndrome patients. The images were reconstructed using conventional FBP and iterative OS-EM and MRP techniques including scatter and nonuniform attenuation corrections. Iterative reconstructions were individually post-filtered. The quantitative results obtained with the brain perfusion phantom were compared with the known actual contrast ratios. The calculated difference from the true values was largest with the FBP method; iteratively reconstructed images proved closer to the reality. Similar findings were obtained in the patient studies. The plain OS-EM method improved the contrast whereas in the case of the MRP technique the improvement in contrast was not so evident with post-filtering. (orig.)

  2. Improvement of brain perfusion SPET using iterative reconstruction with scatter and non-uniform attenuation correction

    International Nuclear Information System (INIS)

    Kauppinen, T.; Vanninen, E.; Kuikka, J.T.; Alenius, S.

    2000-01-01

    Filtered back-projection (FBP) is generally used as the reconstruction method for single-photon emission tomography although it produces noisy images with apparent streak artefacts. It is possible to improve the image quality by using an algorithm with iterative correction steps. The iterative reconstruction technique also has an additional benefit in that computation of attenuation correction can be included in the process. A commonly used iterative method, maximum-likelihood expectation maximisation (ML-EM), can be accelerated using ordered subsets (OS-EM). We have applied to the OS-EM algorithm a Bayesian one-step late correction method utilising median root prior (MRP). Methodological comparison was performed by means of measurements obtained with a brain perfusion phantom and using patient data. The aim of this work was to quantitate the accuracy of iterative reconstruction with scatter and non-uniform attenuation corrections and post-filtering in SPET brain perfusion imaging. SPET imaging was performed using a triple-head gamma camera with fan-beam collimators. Transmission and emission scans were acquired simultaneously. The brain phantom used was a high-resolution three-dimensional anthropomorphic JB003 phantom. Patient studies were performed in ten chronic pain syndrome patients. The images were reconstructed using conventional FBP and iterative OS-EM and MRP techniques including scatter and nonuniform attenuation corrections. Iterative reconstructions were individually post-filtered. The quantitative results obtained with the brain perfusion phantom were compared with the known actual contrast ratios. The calculated difference from the true values was largest with the FBP method; iteratively reconstructed images proved closer to the reality. Similar findings were obtained in the patient studies. The plain OS-EM method improved the contrast whereas in the case of the MRP technique the improvement in contrast was not so evident with post-filtering. (orig.)

  3. Image reconstruction methods in positron tomography

    International Nuclear Information System (INIS)

    Townsend, D.W.; Defrise, M.

    1993-01-01

    In the two decades since the introduction of the X-ray scanner into radiology, medical imaging techniques have become widely established as essential tools in the diagnosis of disease. As a consequence of recent technological and mathematical advances, the non-invasive, three-dimensional imaging of internal organs such as the brain and the heart is now possible, not only for anatomical investigations using X-ray but also for studies which explore the functional status of the body using positron-emitting radioisotopes. This report reviews the historical and physical basis of medical imaging techniques using positron-emitting radioisotopes. Mathematical methods which enable three-dimensional distributions of radioisotopes to be reconstructed from projection data (sinograms) acquired by detectors suitably positioned around the patient are discussed. The extension of conventional two-dimensional tomographic reconstruction algorithms to fully three-dimensional reconstruction is described in detail. (orig.)

  4. Research of ART method in CT image reconstruction

    International Nuclear Information System (INIS)

    Li Zhipeng; Cong Peng; Wu Haifeng

    2005-01-01

    This paper studied Algebraic Reconstruction Technique (ART) in CT image reconstruction. Discussed the ray number influence on image quality. And the adopting of smooth method got high quality CT image. (authors)

  5. Image reconstruction under non-Gaussian noise

    DEFF Research Database (Denmark)

    Sciacchitano, Federica

    During acquisition and transmission, images are often blurred and corrupted by noise. One of the fundamental tasks of image processing is to reconstruct the clean image from a degraded version. The process of recovering the original image from the data is an example of inverse problem. Due...... to the ill-posedness of the problem, the simple inversion of the degradation model does not give any good reconstructions. Therefore, to deal with the ill-posedness it is necessary to use some prior information on the solution or the model and the Bayesian approach. Additive Gaussian noise has been......D thesis intends to solve some of the many open questions for image restoration under non-Gaussian noise. The two main kinds of noise studied in this PhD project are the impulse noise and the Cauchy noise. Impulse noise is due to for instance the malfunctioning pixel elements in the camera sensors, errors...

  6. Proton computed tomography images with algebraic reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Bruzzi, M. [Physics and Astronomy Department, University of Florence, Florence (Italy); Civinini, C.; Scaringella, M. [INFN - Florence Division, Florence (Italy); Bonanno, D. [INFN - Catania Division, Catania (Italy); Brianzi, M. [INFN - Florence Division, Florence (Italy); Carpinelli, M. [INFN - Laboratori Nazionali del Sud, Catania (Italy); Chemistry and Pharmacy Department, University of Sassari, Sassari (Italy); Cirrone, G.A.P.; Cuttone, G. [INFN - Laboratori Nazionali del Sud, Catania (Italy); Presti, D. Lo [INFN - Catania Division, Catania (Italy); Physics and Astronomy Department, University of Catania, Catania (Italy); Maccioni, G. [INFN – Cagliari Division, Cagliari (Italy); Pallotta, S. [INFN - Florence Division, Florence (Italy); Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence (Italy); SOD Fisica Medica, Azienda Ospedaliero-Universitaria Careggi, Firenze (Italy); Randazzo, N. [INFN - Catania Division, Catania (Italy); Romano, F. [INFN - Laboratori Nazionali del Sud, Catania (Italy); Sipala, V. [INFN - Laboratori Nazionali del Sud, Catania (Italy); Chemistry and Pharmacy Department, University of Sassari, Sassari (Italy); Talamonti, C. [INFN - Florence Division, Florence (Italy); Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence (Italy); SOD Fisica Medica, Azienda Ospedaliero-Universitaria Careggi, Firenze (Italy); Vanzi, E. [Fisica Sanitaria, Azienda Ospedaliero-Universitaria Senese, Siena (Italy)

    2017-02-11

    A prototype of proton Computed Tomography (pCT) system for hadron-therapy has been manufactured and tested in a 175 MeV proton beam with a non-homogeneous phantom designed to simulate high-contrast material. BI-SART reconstruction algorithms have been implemented with GPU parallelism, taking into account of most likely paths of protons in matter. Reconstructed tomography images with density resolutions r.m.s. down to ~1% and spatial resolutions <1 mm, achieved within processing times of ~15′ for a 512×512 pixels image prove that this technique will be beneficial if used instead of X-CT in hadron-therapy.

  7. Accelerated Compressed Sensing Based CT Image Reconstruction.

    Science.gov (United States)

    Hashemi, SayedMasoud; Beheshti, Soosan; Gill, Patrick R; Paul, Narinder S; Cobbold, Richard S C

    2015-01-01

    In X-ray computed tomography (CT) an important objective is to reduce the radiation dose without significantly degrading the image quality. Compressed sensing (CS) enables the radiation dose to be reduced by producing diagnostic images from a limited number of projections. However, conventional CS-based algorithms are computationally intensive and time-consuming. We propose a new algorithm that accelerates the CS-based reconstruction by using a fast pseudopolar Fourier based Radon transform and rebinning the diverging fan beams to parallel beams. The reconstruction process is analyzed using a maximum-a-posterior approach, which is transformed into a weighted CS problem. The weights involved in the proposed model are calculated based on the statistical characteristics of the reconstruction process, which is formulated in terms of the measurement noise and rebinning interpolation error. Therefore, the proposed method not only accelerates the reconstruction, but also removes the rebinning and interpolation errors. Simulation results are shown for phantoms and a patient. For example, a 512 × 512 Shepp-Logan phantom when reconstructed from 128 rebinned projections using a conventional CS method had 10% error, whereas with the proposed method the reconstruction error was less than 1%. Moreover, computation times of less than 30 sec were obtained using a standard desktop computer without numerical optimization.

  8. Accelerated Compressed Sensing Based CT Image Reconstruction

    Directory of Open Access Journals (Sweden)

    SayedMasoud Hashemi

    2015-01-01

    Full Text Available In X-ray computed tomography (CT an important objective is to reduce the radiation dose without significantly degrading the image quality. Compressed sensing (CS enables the radiation dose to be reduced by producing diagnostic images from a limited number of projections. However, conventional CS-based algorithms are computationally intensive and time-consuming. We propose a new algorithm that accelerates the CS-based reconstruction by using a fast pseudopolar Fourier based Radon transform and rebinning the diverging fan beams to parallel beams. The reconstruction process is analyzed using a maximum-a-posterior approach, which is transformed into a weighted CS problem. The weights involved in the proposed model are calculated based on the statistical characteristics of the reconstruction process, which is formulated in terms of the measurement noise and rebinning interpolation error. Therefore, the proposed method not only accelerates the reconstruction, but also removes the rebinning and interpolation errors. Simulation results are shown for phantoms and a patient. For example, a 512 × 512 Shepp-Logan phantom when reconstructed from 128 rebinned projections using a conventional CS method had 10% error, whereas with the proposed method the reconstruction error was less than 1%. Moreover, computation times of less than 30 sec were obtained using a standard desktop computer without numerical optimization.

  9. On an image reconstruction method for ECT

    Science.gov (United States)

    Sasamoto, Akira; Suzuki, Takayuki; Nishimura, Yoshihiro

    2007-04-01

    An image by Eddy Current Testing(ECT) is a blurred image to original flaw shape. In order to reconstruct fine flaw image, a new image reconstruction method has been proposed. This method is based on an assumption that a very simple relationship between measured data and source were described by a convolution of response function and flaw shape. This assumption leads to a simple inverse analysis method with deconvolution.In this method, Point Spread Function (PSF) and Line Spread Function(LSF) play a key role in deconvolution processing. This study proposes a simple data processing to determine PSF and LSF from ECT data of machined hole and line flaw. In order to verify its validity, ECT data for SUS316 plate(200x200x10mm) with artificial machined hole and notch flaw had been acquired by differential coil type sensors(produced by ZETEC Inc). Those data were analyzed by the proposed method. The proposed method restored sharp discrete multiple hole image from interfered data by multiple holes. Also the estimated width of line flaw has been much improved compared with original experimental data. Although proposed inverse analysis strategy is simple and easy to implement, its validity to holes and line flaw have been shown by many results that much finer image than original image have been reconstructed.

  10. 3D EIT image reconstruction with GREIT.

    Science.gov (United States)

    Grychtol, Bartłomiej; Müller, Beat; Adler, Andy

    2016-06-01

    Most applications of thoracic EIT use a single plane of electrodes on the chest from which a transverse image 'slice' is calculated. However, interpretation of EIT images is made difficult by the large region above and below the electrode plane to which EIT is sensitive. Volumetric EIT images using two (or more) electrode planes should help compensate, but are little used currently. The Graz consensus reconstruction algorithm for EIT (GREIT) has become popular in lung EIT. One shortcoming of the original formulation of GREIT is its restriction to reconstruction onto a 2D planar image. We present an extension of the GREIT algorithm to 3D and develop open-source tools to evaluate its performance as a function of the choice of stimulation and measurement pattern. Results show 3D GREIT using two electrode layers has significantly more uniform sensitivity profiles through the chest region. Overall, the advantages of 3D EIT are compelling.

  11. Reconstructing building mass models from UAV images

    KAUST Repository

    Li, Minglei; Nan, Liangliang; Smith, Neil; Wonka, Peter

    2015-01-01

    We present an automatic reconstruction pipeline for large scale urban scenes from aerial images captured by a camera mounted on an unmanned aerial vehicle. Using state-of-the-art Structure from Motion and Multi-View Stereo algorithms, we first

  12. Connections model for tomographic images reconstruction

    International Nuclear Information System (INIS)

    Rodrigues, R.G.S.; Pela, C.A.; Roque, S.F. A.C.

    1998-01-01

    This paper shows an artificial neural network with an adequately topology for tomographic image reconstruction. The associated error function is derived and the learning algorithm is make. The simulated results are presented and demonstrate the existence of a generalized solution for nets with linear activation function. (Author)

  13. Dependence of image quality on acquisition time for the PET/CT Biograph mCT

    Energy Technology Data Exchange (ETDEWEB)

    Molina-Duran, Flavia; Glatting, Gerhard [Heidelberg Univ., Mannheim (Germany). Medical Radiation Physics/Radiation Protection; Dinter, Dietmar; Schoenberg, Stefan O. [Heidelberg Univ., Mannheim (Germany). Inst. of Clinical Radiology and Nuclear Medicine; Schoenahl, Frederic [Siemens Healthcare Molecular Imaging, Erlangen (Germany)

    2014-03-01

    The impact of acquisition time on reconstructed PET image quality is analyzed for different acquisition times (1, 2, 3 and 4 min). Image quality was tested according to the National Electrical Manufacturers Association (NEMA) NU 2-2007, the evaluation for the signal to noise ratio (SNR) and the reconstructed activity ratio (RAR) for three algorithms, i.e. OSEM, TrueX and TOF applying different effective iteration numbers. The present work shows that the image quality of 3 and 4 min acquisition time for spherical lesions of 10 mm diameter are not significantly different between TrueX, TOF and OSEM. The 2 min acquisition time should be used carefully for the TrueX and OSEM algorithms in small lesions, because the levels of background noise are high compared to 3 or 4 min measurements. Also, the reconstructed activity ratio is underestimated to be approximately half of the expected value. For large lesions the three algorithms perform similarly for all acquisition durations, however, OSEM has the advantage of a more accurately reconstructed activity ratio compared to TrueX and TOF, which are more strongly influenced by noise. (orig.)

  14. Non-Cartesian parallel imaging reconstruction.

    Science.gov (United States)

    Wright, Katherine L; Hamilton, Jesse I; Griswold, Mark A; Gulani, Vikas; Seiberlich, Nicole

    2014-11-01

    Non-Cartesian parallel imaging has played an important role in reducing data acquisition time in MRI. The use of non-Cartesian trajectories can enable more efficient coverage of k-space, which can be leveraged to reduce scan times. These trajectories can be undersampled to achieve even faster scan times, but the resulting images may contain aliasing artifacts. Just as Cartesian parallel imaging can be used to reconstruct images from undersampled Cartesian data, non-Cartesian parallel imaging methods can mitigate aliasing artifacts by using additional spatial encoding information in the form of the nonhomogeneous sensitivities of multi-coil phased arrays. This review will begin with an overview of non-Cartesian k-space trajectories and their sampling properties, followed by an in-depth discussion of several selected non-Cartesian parallel imaging algorithms. Three representative non-Cartesian parallel imaging methods will be described, including Conjugate Gradient SENSE (CG SENSE), non-Cartesian generalized autocalibrating partially parallel acquisition (GRAPPA), and Iterative Self-Consistent Parallel Imaging Reconstruction (SPIRiT). After a discussion of these three techniques, several potential promising clinical applications of non-Cartesian parallel imaging will be covered. © 2014 Wiley Periodicals, Inc.

  15. 3-D Reconstruction From Satellite Images

    DEFF Research Database (Denmark)

    Denver, Troelz

    1999-01-01

    of planetary surfaces, but other purposes is considered as well. The system performance is measured with respect to the precision and the time consumption.The reconstruction process is divided into four major areas: Acquisition, calibration, matching/reconstruction and presentation. Each of these areas...... are treated individually. A detailed treatment of various lens distortions is required, in order to correct for these problems. This subject is included in the acquisition part. In the calibration part, the perspective distortion is removed from the images. Most attention has been paid to the matching problem...

  16. Study on the usefulness of whole body SPECT coronal image, MIP image in 67Ga scintigraphy

    International Nuclear Information System (INIS)

    Kawamura, Seiji

    2002-01-01

    In this study, we examined the usefulness of whole body coronal images and whole body cine display MIP images (CMIP) upon which image processing was carried out after whole body SPECT in comparison to the usefulness of whole body images (WB/SC) compensated by scattered radiation in tumor/inflammation scintigraphy with 67 Ga-citrate ( 67 Ga). Image interpretation was performed for the 120 patients with confirmed diagnoses, and the accuracy of their diagnoses was studied by three nuclear medical physicians and two clinical radiological technologists by means of sensitivity, specificity and ROC analysis. The resultant data show that sensitivity, specificity, accuracy and the area under the ROC curve Az in the WB/SC were approximately 65%, 86%, 74% and 0.724, respectively, whereas sensitivity, specificity, accuracy and Az of the image reading system in which CMIP is combined with whole body coronal images reconstructed by the OS-EM method were approximately 93%, 95%, 94% and 0.860, respectively. Furthermore, coronal images reconstructed by the OS-EM method tended to be superior to those produced by the FBP method in both diagnostic accuracy and ROC analysis. In conclusion, the image reading system in which CMIP is combined with whole body coronal images reconstructed by the OS-EM method was shown to be superior in diagnostic accuracy and ROC analysis. Our data suggest that whole body SPECT is an excellent technique as an alternative to WB/SC. (author)

  17. Performance measurement of PSF modeling reconstruction (True X) on Siemens Biograph TruePoint TrueV PET/CT.

    Science.gov (United States)

    Lee, Young Sub; Kim, Jin Su; Kim, Kyeong Min; Kang, Joo Hyun; Lim, Sang Moo; Kim, Hee-Joung

    2014-05-01

    The Siemens Biograph TruePoint TrueV (B-TPTV) positron emission tomography (PET) scanner performs 3D PET reconstruction using a system matrix with point spread function (PSF) modeling (called the True X reconstruction). PET resolution was dramatically improved with the True X method. In this study, we assessed the spatial resolution and image quality on a B-TPTV PET scanner. In addition, we assessed the feasibility of animal imaging with a B-TPTV PET and compared it with a microPET R4 scanner. Spatial resolution was measured at center and at 8 cm offset from the center in transverse plane with warm background activity. True X, ordered subset expectation maximization (OSEM) without PSF modeling, and filtered back-projection (FBP) reconstruction methods were used. Percent contrast (% contrast) and percent background variability (% BV) were assessed according to NEMA NU2-2007. The recovery coefficient (RC), non-uniformity, spill-over ratio (SOR), and PET imaging of the Micro Deluxe Phantom were assessed to compare image quality of B-TPTV PET with that of the microPET R4. When True X reconstruction was used, spatial resolution was RC with True X reconstruction was higher than that with the FBP method and the OSEM without PSF modeling method on the microPET R4. The non-uniformity with True X reconstruction was higher than that with FBP and OSEM without PSF modeling on microPET R4. SOR with True X reconstruction was better than that with FBP or OSEM without PSF modeling on the microPET R4. This study assessed the performance of the True X reconstruction. Spatial resolution with True X reconstruction was improved by 45 % and its % contrast was significantly improved compared to those with the conventional OSEM without PSF modeling reconstruction algorithm. The noise level was higher than that with the other reconstruction algorithm. Therefore, True X reconstruction should be used with caution when quantifying PET data.

  18. Evaluation of reconstruction techniques in regional cerebral blood flow SPECT using trade-off plots: a Monte Carlo study.

    Science.gov (United States)

    Olsson, Anna; Arlig, Asa; Carlsson, Gudrun Alm; Gustafsson, Agnetha

    2007-09-01

    The image quality of single photon emission computed tomography (SPECT) depends on the reconstruction algorithm used. The purpose of the present study was to evaluate parameters in ordered subset expectation maximization (OSEM) and to compare systematically with filtered back-projection (FBP) for reconstruction of regional cerebral blood flow (rCBF) SPECT, incorporating attenuation and scatter correction. The evaluation was based on the trade-off between contrast recovery and statistical noise using different sizes of subsets, number of iterations and filter parameters. Monte Carlo simulated SPECT studies of a digital human brain phantom were used. The contrast recovery was calculated as measured contrast divided by true contrast. Statistical noise in the reconstructed images was calculated as the coefficient of variation in pixel values. A constant contrast level was reached above 195 equivalent maximum likelihood expectation maximization iterations. The choice of subset size was not crucial as long as there were > or = 2 projections per subset. The OSEM reconstruction was found to give 5-14% higher contrast recovery than FBP for all clinically relevant noise levels in rCBF SPECT. The Butterworth filter, power 6, achieved the highest stable contrast recovery level at all clinically relevant noise levels. The cut-off frequency should be chosen according to the noise level accepted in the image. Trade-off plots are shown to be a practical way of deciding the number of iterations and subset size for the OSEM reconstruction and can be used for other examination types in nuclear medicine.

  19. Reconstructing building mass models from UAV images

    KAUST Repository

    Li, Minglei

    2015-07-26

    We present an automatic reconstruction pipeline for large scale urban scenes from aerial images captured by a camera mounted on an unmanned aerial vehicle. Using state-of-the-art Structure from Motion and Multi-View Stereo algorithms, we first generate a dense point cloud from the aerial images. Based on the statistical analysis of the footprint grid of the buildings, the point cloud is classified into different categories (i.e., buildings, ground, trees, and others). Roof structures are extracted for each individual building using Markov random field optimization. Then, a contour refinement algorithm based on pivot point detection is utilized to refine the contour of patches. Finally, polygonal mesh models are extracted from the refined contours. Experiments on various scenes as well as comparisons with state-of-the-art reconstruction methods demonstrate the effectiveness and robustness of the proposed method.

  20. Homotopy Based Reconstruction from Acoustic Images

    DEFF Research Database (Denmark)

    Sharma, Ojaswa

    of the inherent arrangement. The problem of reconstruction from arbitrary cross sections is a generic problem and is also shown to be solved here using the mathematical tool of continuous deformations. As part of a complete processing, segmentation using level set methods is explored for acoustic images and fast...... GPU (Graphics Processing Unit) based methods are suggested for a streaming computation on large volumes of data. Validation of results for acoustic images is not straightforward due to unavailability of ground truth. Accuracy figures for the suggested methods are provided using phantom object...

  1. Image reconstruction of dynamic infrared single-pixel imaging system

    Science.gov (United States)

    Tong, Qi; Jiang, Yilin; Wang, Haiyan; Guo, Limin

    2018-03-01

    Single-pixel imaging technique has recently received much attention. Most of the current single-pixel imaging is aimed at relatively static targets or the imaging system is fixed, which is limited by the number of measurements received through the single detector. In this paper, we proposed a novel dynamic compressive imaging method to solve the imaging problem, where exists imaging system motion behavior, for the infrared (IR) rosette scanning system. The relationship between adjacent target images and scene is analyzed under different system movement scenarios. These relationships are used to build dynamic compressive imaging models. Simulation results demonstrate that the proposed method can improve the reconstruction quality of IR image and enhance the contrast between the target and the background in the presence of system movement.

  2. Study on the usefulness of whole body SPECT coronal image, MIP image in {sup 67}Ga scintigraphy

    Energy Technology Data Exchange (ETDEWEB)

    Kawamura, Seiji [Kurume Univ., Fukuoka (Japan). Hospital; Ishibashi, Masatoshi; Kurata, Seiji; Morita, Seiichirou; Hayabuchi, Naofumi [Kurume Univ., Fukuoka (Japan). School of Medicine; Fukushima, Shigehiro [Kyushu Inst. of Design, Fukuoka (Japan). Graduate School of Auditory and Visual Communication Sciences; Umezaki, Noriyoshi [Daiichi Coll. of Pharmaceutical Sciences, Fukuoka (Japan)

    2002-05-01

    In this study, we examined the usefulness of whole body coronal images and whole body cine display MIP images (CMIP) upon which image processing was carried out after whole body SPECT in comparison to the usefulness of whole body images (WB/SC) compensated by scattered radiation in tumor/inflammation scintigraphy with {sup 67}Ga-citrate ({sup 67}Ga). Image interpretation was performed for the 120 patients with confirmed diagnoses, and the accuracy of their diagnoses was studied by three nuclear medical physicians and two clinical radiological technologists by means of sensitivity, specificity and ROC analysis. The resultant data show that sensitivity, specificity, accuracy and the area under the ROC curve Az in the WB/SC were approximately 65%, 86%, 74% and 0.724, respectively, whereas sensitivity, specificity, accuracy and Az of the image reading system in which CMIP is combined with whole body coronal images reconstructed by the OS-EM method were approximately 93%, 95%, 94% and 0.860, respectively. Furthermore, coronal images reconstructed by the OS-EM method tended to be superior to those produced by the FBP method in both diagnostic accuracy and ROC analysis. In conclusion, the image reading system in which CMIP is combined with whole body coronal images reconstructed by the OS-EM method was shown to be superior in diagnostic accuracy and ROC analysis. Our data suggest that whole body SPECT is an excellent technique as an alternative to WB/SC. (author)

  3. Image-reconstruction methods in positron tomography

    CERN Document Server

    Townsend, David W; CERN. Geneva

    1993-01-01

    Physics and mathematics for medical imaging In the two decades since the introduction of the X-ray scanner into radiology, medical imaging techniques have become widely established as essential tools in the diagnosis of disease. As a consequence of recent technological and mathematical advances, the non-invasive, three-dimensional imaging of internal organs such as the brain and the heart is now possible, not only for anatomical investigations using X-rays but also for studies which explore the functional status of the body using positron-emitting radioisotopes and nuclear magnetic resonance. Mathematical methods which enable three-dimentional distributions to be reconstructed from projection data acquired by radiation detectors suitably positioned around the patient will be described in detail. The lectures will trace the development of medical imaging from simpleradiographs to the present-day non-invasive measurement of in vivo boichemistry. Powerful techniques to correlate anatomy and function that are cur...

  4. Three-dimensional reconstruction of CT images

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, Toshiaki; Kattoh, Keiichi; Kawakami, Genichiroh; Igami, Isao; Mariya, Yasushi; Nakamura, Yasuhiko; Saitoh, Yohko; Tamura, Koreroku; Shinozaki, Tatsuyo

    1986-09-01

    Computed tomography (CT) has the ability to provide sensitive visualization of organs and lesions. Owing to the nature of CT to be transaxial images, a structure which is greater than a certain size appears as several serial CT images. Consequently each observer must reconstruct those images into a three-dimensional (3-D) form mentally. It has been supposed to be of great use if such a 3-D form can be described as a definite figure. A new computer program has been developed which can produce 3-D figures from the profiles of organs and lesions on CT images using spline curves. The figures obtained through this method are regarded to have practical applications.

  5. Simulated annealing image reconstruction for positron emission tomography

    Energy Technology Data Exchange (ETDEWEB)

    Sundermann, E; Lemahieu, I; Desmedt, P [Department of Electronics and Information Systems, University of Ghent, St. Pietersnieuwstraat 41, B-9000 Ghent, Belgium (Belgium)

    1994-12-31

    In Positron Emission Tomography (PET) images have to be reconstructed from moisy projection data. The noise on the PET data can be modeled by a Poison distribution. In this paper, we present the results of using the simulated annealing technique to reconstruct PET images. Various parameter settings of the simulated annealing algorithm are discussed and optimized. The reconstructed images are of good quality and high contrast, in comparison to other reconstruction techniques. (authors). 11 refs., 2 figs.

  6. Simulated annealing image reconstruction for positron emission tomography

    International Nuclear Information System (INIS)

    Sundermann, E.; Lemahieu, I.; Desmedt, P.

    1994-01-01

    In Positron Emission Tomography (PET) images have to be reconstructed from moisy projection data. The noise on the PET data can be modeled by a Poison distribution. In this paper, we present the results of using the simulated annealing technique to reconstruct PET images. Various parameter settings of the simulated annealing algorithm are discussed and optimized. The reconstructed images are of good quality and high contrast, in comparison to other reconstruction techniques. (authors)

  7. Fully 3-D list-mode positron emission tomography image reconstruction on a multi-GPU cluster

    Energy Technology Data Exchange (ETDEWEB)

    Cui, Jingyu [Stanford Univ., CA (United States). Dept. of Electrical Engineering; Prevrhal, Sven; Shao, Lingxiong [Philips Healthcare, San Jose, CA (United States); Pratx, Guillem [Stanford Univ., CA (United States). Dept. of Radiation Oncology; Levin, Craig S. [Stanford Univ., CA (United States). Dept. of Radiology, Electrical Engineering, and Physics; Stanford Univ., CA (United States). Molecular Imaging Program at Stanford (MIPS); Stanford Univ., CA (United States). School of Medicine

    2011-07-01

    List-mode processing is an efficient way of dealing with the sparse nature of PET data sets, and is the processing method of choice for time-of-flight (ToF) PET. We present a novel method of computing line projection operations required for list-mode ordered subsets expectation maximization (OSEM) for fully 3-D PET image reconstruction on a graphics processing unit (GPU) using the compute unified device architecture (CUDA) framework. Our method overcomes challenges such as compute thread divergence, and exploits GPU capabilities such as shared memory and atomic operations. When applied to line projection operations for list-mode time-of-flight PET, this new GPU-CUDA reformulation is 188X faster than a single-threaded reference CPU implementation. When embedded in a multi-process environment on a GPU-equipped small cluster, a speedup of 4X was observed over the same configuration but without GPU support. Image quality is preserved with root mean squared (RMS) deviation of 0.05% between CPU and GPU-generated images, which has negligible effect in typical clinical applications. (orig.)

  8. Image reconstruction. Application to transverse axial tomography

    International Nuclear Information System (INIS)

    Aubry, Florent.

    1977-09-01

    A method of computerized tridimensional image reconstruction from their projection, especially in the computerized transverse axial tomography is suggested. First, the different techniques actually developped and presented in the literature are analyzed. Then, the equipment used is briefly described. The reconstruction algorithm developped is presented. This algorithm is based on the convolution method, well adapted to the real conditions of exploitation. It is an extension of SHEPP and LOGAN's algorithm. A correction of the self absorption and of the detector's response is proposed. Finally, the first results obtained which are satisfactory are given. The simplicity of the method which does not need a too long computation time makes possible the implementation of the algorithm on a mini-computer [fr

  9. Reconstruction of Novel Viewpoint Image Using GRNN

    Institute of Scientific and Technical Information of China (English)

    李战委; 孙济洲; 张志强

    2003-01-01

    A neural-statistical approach to the reconstruction of novel viewpoint image using general regression neural networks(GRNN) is presented. Different color value will be obtained by watching the same surface point of an object from different viewpoints due to specular reflection, and the difference is related to the position of viewpoint. The relationship between the position of viewpoint and the color of image is non-linear, neural network is introduced to make curve fitting, where the inputs of neural network are only a few calibrated images with obvious specular reflection. By training the neural network, network model is obtained. By inputing an arbitrary virtual viewpoint to the model, the image of the virtual viewpoint can be computed. By using the method presented here, novel viewpoint image with photo-realistic property can be obtained, especially images with obvious specular reflection can accurately be generated. The method is an image-based rendering method, geometric model of the scene and position of lighting are not needed.

  10. [Application of N-isopropyl-p-[123I] iodoamphetamine quantification of regional cerebral blood flow using iterative reconstruction methods: selection of the optimal reconstruction method and optimization of the cutoff frequency of the preprocessing filter].

    Science.gov (United States)

    Asazu, Akira; Hayashi, Masuo; Arai, Mami; Kumai, Yoshiaki; Akagi, Hiroyuki; Okayama, Katsuyoshi; Narumi, Yoshifumi

    2013-05-01

    In cerebral blood flow tests using N-Isopropyl-p-[123I] Iodoamphetamine "I-IMP, quantitative results of greater accuracy than possible using the autoradiography (ARG) method can be obtained with attenuation and scatter correction and image reconstruction by filtered back projection (FBP). However, the cutoff frequency of the preprocessing Butterworth filter affects the quantitative value; hence, we sought an optimal cutoff frequency, derived from the correlation between the FBP method and Xenon-enhanced computed tomography (XeCT)/cerebral blood flow (CBF). In this study, we reconstructed images using ordered subsets expectation maximization (OSEM), a method of successive approximation which has recently come into wide use, and also three-dimensional (3D)-OSEM, a method by which the resolution can be corrected with the addition of collimator broad correction, to examine the effects on the regional cerebral blood flow (rCBF) quantitative value of changing the cutoff frequency, and to determine whether successive approximation is applicable to cerebral blood flow quantification. Our results showed that quantification of greater accuracy was obtained with reconstruction employing the 3D-OSEM method and using a cutoff frequency set near 0.75-0.85 cycles/cm, which is higher than the frequency used in image reconstruction by the ordinary FBP method.

  11. Application of N-isopropyl-p-[123I] iodoamphetamine quantification of regional cerebral blood flow using iterative reconstruction methods. Selection of the optimal reconstruction method and optimization of the cutoff frequency of the preprocessing filter

    International Nuclear Information System (INIS)

    Asazu, Akira; Hayashi, Masuo; Arai, Mami; Kumai, Yoshiaki; Akagi, Hiroyuki; Okayama, Katsuyoshi; Narumi, Yoshifumi

    2013-01-01

    In cerebral blood flow tests using N-Isopropyl-p-[ 123 I] Iodoamphetamine 123 I-IMP, quantitative results of greater accuracy than possible using the autoradiography (ARG) method can be obtained with attenuation and scatter correction and image reconstruction by filtered back projection (FBP). However, the cutoff frequency of the preprocessing Butterworth filter affects the quantitative value; hence, we sought an optimal cutoff frequency, derived from the correlation between the FBP method and Xenon-enhanced computed tomography (XeCT)/cerebral blood flow (CBF). In this study, we reconstructed images using ordered subsets expectation maximization (OSEM), a method of successive approximation which has recently come into wide use, and also three-dimensional (3D)-OSEM, a method by which the resolution can be corrected with the addition of collimator broad correction, to examine the effects on the regional cerebral blood flow (rCBF) quantitative value of changing the cutoff frequency, and to determine whether successive approximation is applicable to cerebral blood flow quantification. Our results showed that quantification of greater accuracy was obtained with reconstruction employing the 3D-OSEM method and using a cutoff frequency set near 0.75-0.85 cycles/cm, which is higher than the frequency used in image reconstruction by the ordinary FBP method. (author)

  12. Prior image constrained image reconstruction in emerging computed tomography applications

    Science.gov (United States)

    Brunner, Stephen T.

    Advances have been made in computed tomography (CT), especially in the past five years, by incorporating prior images into the image reconstruction process. In this dissertation, we investigate prior image constrained image reconstruction in three emerging CT applications: dual-energy CT, multi-energy photon-counting CT, and cone-beam CT in image-guided radiation therapy. First, we investigate the application of Prior Image Constrained Compressed Sensing (PICCS) in dual-energy CT, which has been called "one of the hottest research areas in CT." Phantom and animal studies are conducted using a state-of-the-art 64-slice GE Discovery 750 HD CT scanner to investigate the extent to which PICCS can enable radiation dose reduction in material density and virtual monochromatic imaging. Second, we extend the application of PICCS from dual-energy CT to multi-energy photon-counting CT, which has been called "one of the 12 topics in CT to be critical in the next decade." Numerical simulations are conducted to generate multiple energy bin images for a photon-counting CT acquisition and to investigate the extent to which PICCS can enable radiation dose efficiency improvement. Third, we investigate the performance of a newly proposed prior image constrained scatter correction technique to correct scatter-induced shading artifacts in cone-beam CT, which, when used in image-guided radiation therapy procedures, can assist in patient localization, and potentially, dose verification and adaptive radiation therapy. Phantom studies are conducted using a Varian 2100 EX system with an on-board imager to investigate the extent to which the prior image constrained scatter correction technique can mitigate scatter-induced shading artifacts in cone-beam CT. Results show that these prior image constrained image reconstruction techniques can reduce radiation dose in dual-energy CT by 50% in phantom and animal studies in material density and virtual monochromatic imaging, can lead to radiation

  13. Evaluation of the parameters of SPECT images for yttrium-90 in radiosinoviorthesis; Avaliação dos parâmetros de aquisição de imagens SPECT para ítrio-90 em radiosinoviortese

    Energy Technology Data Exchange (ETDEWEB)

    Toledo, B.C. de; Sáa, L.V. de, E-mail: bruce.de.toledo@gmail.com [Instituto de Radioproteção e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil). Física Médica; Ramos, S.M.; Coelho, F.A.; Thomas, S.; Souza, S.A. de; Pinheiro, M.A. [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Hospital Universitário Clementino Fraga Filho

    2017-07-01

    Introduction: the evaluation of the distribution of radioactive material in the articulation by SPECT images after radiosinoviorthesis (RSO) can guarantee the efficacy of this therapy. However, Bremsstrahlung image quality has major limitations, necessitating studies on SPECT image acquisition parameters and yttrium-90 image reconstruction methods. Methods: SPECT images were obtained from an acrylic simulator containing four cylindrical inserts to simulate capturing lesions. The images were obtained with collimators of high, medium and low (HEGP, MEGP and LEHR) energy; 130 keV power window, 70% width and 64 x 64 matrix. The reconstruction methods used were: FBP and OSEM with different filters. Results: 45 results found. The images obtained with the MEGP and HEGP collimators presented better results than those obtained with the LEHR collimator. The OSEM reconstructions were superior when the MEGP and HEGP collimators were used. Conclusions: The acquisition of yttrium-90 SPECT images with MEGP collimators showed higher sensitivity, whereas those obtained with HEPG collimators presented lower noise. The image reconstruction methods have relevant importance in the image quality, showing a significant difference between the FBP and OSEM reconstructions and between the filters used.

  14. Optimized Quasi-Interpolators for Image Reconstruction.

    Science.gov (United States)

    Sacht, Leonardo; Nehab, Diego

    2015-12-01

    We propose new quasi-interpolators for the continuous reconstruction of sampled images, combining a narrowly supported piecewise-polynomial kernel and an efficient digital filter. In other words, our quasi-interpolators fit within the generalized sampling framework and are straightforward to use. We go against standard practice and optimize for approximation quality over the entire Nyquist range, rather than focusing exclusively on the asymptotic behavior as the sample spacing goes to zero. In contrast to previous work, we jointly optimize with respect to all degrees of freedom available in both the kernel and the digital filter. We consider linear, quadratic, and cubic schemes, offering different tradeoffs between quality and computational cost. Experiments with compounded rotations and translations over a range of input images confirm that, due to the additional degrees of freedom and the more realistic objective function, our new quasi-interpolators perform better than the state of the art, at a similar computational cost.

  15. Cardiac-gated parametric images from 82 Rb PET from dynamic frames and direct 4D reconstruction.

    Science.gov (United States)

    Germino, Mary; Carson, Richard E

    2018-02-01

    Cardiac perfusion PET data can be reconstructed as a dynamic sequence and kinetic modeling performed to quantify myocardial blood flow, or reconstructed as static gated images to quantify function. Parametric images from dynamic PET are conventionally not gated, to allow use of all events with lower noise. An alternative method for dynamic PET is to incorporate the kinetic model into the reconstruction algorithm itself, bypassing the generation of a time series of emission images and directly producing parametric images. So-called "direct reconstruction" can produce parametric images with lower noise than the conventional method because the noise distribution is more easily modeled in projection space than in image space. In this work, we develop direct reconstruction of cardiac-gated parametric images for 82 Rb PET with an extension of the Parametric Motion compensation OSEM List mode Algorithm for Resolution-recovery reconstruction for the one tissue model (PMOLAR-1T). PMOLAR-1T was extended to accommodate model terms to account for spillover from the left and right ventricles into the myocardium. The algorithm was evaluated on a 4D simulated 82 Rb dataset, including a perfusion defect, as well as a human 82 Rb list mode acquisition. The simulated list mode was subsampled into replicates, each with counts comparable to one gate of a gated acquisition. Parametric images were produced by the indirect (separate reconstructions and modeling) and direct methods for each of eight low-count and eight normal-count replicates of the simulated data, and each of eight cardiac gates for the human data. For the direct method, two initialization schemes were tested: uniform initialization, and initialization with the filtered iteration 1 result of the indirect method. For the human dataset, event-by-event respiratory motion compensation was included. The indirect and direct methods were compared for the simulated dataset in terms of bias and coefficient of variation as a

  16. Image reconstruction design of industrial CT instrument for teaching

    International Nuclear Information System (INIS)

    Zou Yongning; Cai Yufang

    2009-01-01

    Industrial CT instrument for teaching is applied to teaching and study in field of physics and radiology major, image reconstruction is an important part of software on CT instrument. The paper expatiate on CT physical theory and first generation CT reconstruction algorithm, describe scan process of industrial CT instrument for teaching; analyze image artifact as result of displacement of rotation center, implement method of center displacement correcting, design and complete image reconstruction software, application shows that reconstructed image is very clear and qualitatively high. (authors)

  17. Sparse BLIP: BLind Iterative Parallel imaging reconstruction using compressed sensing.

    Science.gov (United States)

    She, Huajun; Chen, Rong-Rong; Liang, Dong; DiBella, Edward V R; Ying, Leslie

    2014-02-01

    To develop a sensitivity-based parallel imaging reconstruction method to reconstruct iteratively both the coil sensitivities and MR image simultaneously based on their prior information. Parallel magnetic resonance imaging reconstruction problem can be formulated as a multichannel sampling problem where solutions are sought analytically. However, the channel functions given by the coil sensitivities in parallel imaging are not known exactly and the estimation error usually leads to artifacts. In this study, we propose a new reconstruction algorithm, termed Sparse BLind Iterative Parallel, for blind iterative parallel imaging reconstruction using compressed sensing. The proposed algorithm reconstructs both the sensitivity functions and the image simultaneously from undersampled data. It enforces the sparseness constraint in the image as done in compressed sensing, but is different from compressed sensing in that the sensing matrix is unknown and additional constraint is enforced on the sensitivities as well. Both phantom and in vivo imaging experiments were carried out with retrospective undersampling to evaluate the performance of the proposed method. Experiments show improvement in Sparse BLind Iterative Parallel reconstruction when compared with Sparse SENSE, JSENSE, IRGN-TV, and L1-SPIRiT reconstructions with the same number of measurements. The proposed Sparse BLind Iterative Parallel algorithm reduces the reconstruction errors when compared to the state-of-the-art parallel imaging methods. Copyright © 2013 Wiley Periodicals, Inc.

  18. Blind compressed sensing image reconstruction based on alternating direction method

    Science.gov (United States)

    Liu, Qinan; Guo, Shuxu

    2018-04-01

    In order to solve the problem of how to reconstruct the original image under the condition of unknown sparse basis, this paper proposes an image reconstruction method based on blind compressed sensing model. In this model, the image signal is regarded as the product of a sparse coefficient matrix and a dictionary matrix. Based on the existing blind compressed sensing theory, the optimal solution is solved by the alternative minimization method. The proposed method solves the problem that the sparse basis in compressed sensing is difficult to represent, which restrains the noise and improves the quality of reconstructed image. This method ensures that the blind compressed sensing theory has a unique solution and can recover the reconstructed original image signal from a complex environment with a stronger self-adaptability. The experimental results show that the image reconstruction algorithm based on blind compressed sensing proposed in this paper can recover high quality image signals under the condition of under-sampling.

  19. Reproducibility of F18-FDG PET radiomic features for different cervical tumor segmentation methods, gray-level discretization, and reconstruction algorithms.

    Science.gov (United States)

    Altazi, Baderaldeen A; Zhang, Geoffrey G; Fernandez, Daniel C; Montejo, Michael E; Hunt, Dylan; Werner, Joan; Biagioli, Matthew C; Moros, Eduardo G

    2017-11-01

    Site-specific investigations of the role of radiomics in cancer diagnosis and therapy are emerging. We evaluated the reproducibility of radiomic features extracted from 18 Flourine-fluorodeoxyglucose ( 18 F-FDG) PET images for three parameters: manual versus computer-aided segmentation methods, gray-level discretization, and PET image reconstruction algorithms. Our cohort consisted of pretreatment PET/CT scans from 88 cervical cancer patients. Two board-certified radiation oncologists manually segmented the metabolic tumor volume (MTV 1 and MTV 2 ) for each patient. For comparison, we used a graphical-based method to generate semiautomated segmented volumes (GBSV). To address any perturbations in radiomic feature values, we down-sampled the tumor volumes into three gray-levels: 32, 64, and 128 from the original gray-level of 256. Finally, we analyzed the effect on radiomic features on PET images of eight patients due to four PET 3D-reconstruction algorithms: maximum likelihood-ordered subset expectation maximization (OSEM) iterative reconstruction (IR) method, fourier rebinning-ML-OSEM (FOREIR), FORE-filtered back projection (FOREFBP), and 3D-Reprojection (3DRP) analytical method. We extracted 79 features from all segmentation method, gray-levels of down-sampled volumes, and PET reconstruction algorithms. The features were extracted using gray-level co-occurrence matrices (GLCM), gray-level size zone matrices (GLSZM), gray-level run-length matrices (GLRLM), neighborhood gray-tone difference matrices (NGTDM), shape-based features (SF), and intensity histogram features (IHF). We computed the Dice coefficient between each MTV and GBSV to measure segmentation accuracy. Coefficient values close to one indicate high agreement, and values close to zero indicate low agreement. We evaluated the effect on radiomic features by calculating the mean percentage differences (d¯) between feature values measured from each pair of parameter elements (i.e. segmentation methods: MTV

  20. Image reconstruction by domain-transform manifold learning

    Science.gov (United States)

    Zhu, Bo; Liu, Jeremiah Z.; Cauley, Stephen F.; Rosen, Bruce R.; Rosen, Matthew S.

    2018-03-01

    Image reconstruction is essential for imaging applications across the physical and life sciences, including optical and radar systems, magnetic resonance imaging, X-ray computed tomography, positron emission tomography, ultrasound imaging and radio astronomy. During image acquisition, the sensor encodes an intermediate representation of an object in the sensor domain, which is subsequently reconstructed into an image by an inversion of the encoding function. Image reconstruction is challenging because analytic knowledge of the exact inverse transform may not exist a priori, especially in the presence of sensor non-idealities and noise. Thus, the standard reconstruction approach involves approximating the inverse function with multiple ad hoc stages in a signal processing chain, the composition of which depends on the details of each acquisition strategy, and often requires expert parameter tuning to optimize reconstruction performance. Here we present a unified framework for image reconstruction—automated transform by manifold approximation (AUTOMAP)—which recasts image reconstruction as a data-driven supervised learning task that allows a mapping between the sensor and the image domain to emerge from an appropriate corpus of training data. We implement AUTOMAP with a deep neural network and exhibit its flexibility in learning reconstruction transforms for various magnetic resonance imaging acquisition strategies, using the same network architecture and hyperparameters. We further demonstrate that manifold learning during training results in sparse representations of domain transforms along low-dimensional data manifolds, and observe superior immunity to noise and a reduction in reconstruction artefacts compared with conventional handcrafted reconstruction methods. In addition to improving the reconstruction performance of existing acquisition methodologies, we anticipate that AUTOMAP and other learned reconstruction approaches will accelerate the development

  1. SPECT imaging with resolution recovery

    International Nuclear Information System (INIS)

    Bronnikov, A. V.

    2011-01-01

    Single-photon emission computed tomography (SPECT) is a method of choice for imaging spatial distributions of radioisotopes. Many applications of this method are found in nuclear industry, medicine, and biomedical research. We study mathematical modeling of a micro-SPECT system by using a point-spread function (PSF) and implement an OSEM-based iterative algorithm for image reconstruction with resolution recovery. Unlike other known implementations of the OSEM algorithm, we apply en efficient computation scheme based on a useful approximation of the PSF, which ensures relatively fast computations. The proposed approach can be applied with the data acquired with any type of collimators, including parallel-beam fan-beam, cone-beam and pinhole collimators. Experimental results obtained with a micro SPECT system demonstrate high efficiency of resolution recovery. (authors)

  2. A fast image reconstruction technique based on ART

    International Nuclear Information System (INIS)

    Zhang Shunli; Zhang Dinghua; Wang Kai; Huang Kuidong; Li Weibin

    2007-01-01

    Algebraic Reconstruction Technique (ART) is an iterative method for image reconstruction. Improving its reconstruction speed has been one of the important researching aspects of ART. For the simplified weight coefficients reconstruction model of ART, a fast grid traverse algorithm is proposed, which can determine the grid index by simple operations such as addition, subtraction and comparison. Since the weight coefficients are calculated at real time during iteration, large amount of storage is saved and the reconstruction speed is greatly increased. Experimental results show that the new algorithm is very effective and the reconstruction speed is improved about 10 times compared with the traditional algorithm. (authors)

  3. Photogrammetric 3D reconstruction using mobile imaging

    Science.gov (United States)

    Fritsch, Dieter; Syll, Miguel

    2015-03-01

    In our paper we demonstrate the development of an Android Application (AndroidSfM) for photogrammetric 3D reconstruction that works on smartphones and tablets likewise. The photos are taken with mobile devices, and can thereafter directly be calibrated using standard calibration algorithms of photogrammetry and computer vision, on that device. Due to still limited computing resources on mobile devices, a client-server handshake using Dropbox transfers the photos to the sever to run AndroidSfM for the pose estimation of all photos by Structure-from-Motion and, thereafter, uses the oriented bunch of photos for dense point cloud estimation by dense image matching algorithms. The result is transferred back to the mobile device for visualization and ad-hoc on-screen measurements.

  4. Reconstruction from gamma radiography and ultrasonic images

    International Nuclear Information System (INIS)

    Gautier, S.; Lavayssiere, B.; Idier, J.; Mohammad-Djafari, A.

    1998-02-01

    This work deals with the three-dimensional reconstruction from gamma radiographic and ultrasonic images. Such an issue belongs to the field of data fusion since the data provide complementary information. The two sets of data are independently related to two sets of parameters: gamma ray attenuation and ultrasonic reflectivity. The fusion problem is addressed in a Bayesian framework; the kingpin of the task is then to define a joint a priori model for both attenuation and reflectivity. Thus, the developing of this model and the entailed joint estimation constitute the principal contribution of this work. The results of real data treatments demonstrate the validity of this method as compared to a sequential approach of the two sets of data

  5. Model-Based Reconstructive Elasticity Imaging Using Ultrasound

    Directory of Open Access Journals (Sweden)

    Salavat R. Aglyamov

    2007-01-01

    Full Text Available Elasticity imaging is a reconstructive imaging technique where tissue motion in response to mechanical excitation is measured using modern imaging systems, and the estimated displacements are then used to reconstruct the spatial distribution of Young's modulus. Here we present an ultrasound elasticity imaging method that utilizes the model-based technique for Young's modulus reconstruction. Based on the geometry of the imaged object, only one axial component of the strain tensor is used. The numerical implementation of the method is highly efficient because the reconstruction is based on an analytic solution of the forward elastic problem. The model-based approach is illustrated using two potential clinical applications: differentiation of liver hemangioma and staging of deep venous thrombosis. Overall, these studies demonstrate that model-based reconstructive elasticity imaging can be used in applications where the geometry of the object and the surrounding tissue is somewhat known and certain assumptions about the pathology can be made.

  6. SU-D-201-05: Phantom Study to Determine Optimal PET Reconstruction Parameters for PET/MR Imaging of Y-90 Microspheres Following Radioembolization

    Energy Technology Data Exchange (ETDEWEB)

    Maughan, N [Washington University in Saint Louis, Saint Louis, MO (United States); Conti, M [Siemens Healthcare Molecular Imaging, Knoxville, TN (United States); Parikh, P [Washington Univ. School of Medicine, Saint Louis, MO (United States); Faul, D [Siemens Healthcare, New York, NY (United States); Laforest, R [Washington University School of Medicine, Saint Louis, MO (United States)

    2015-06-15

    Purpose: Imaging Y-90 microspheres with PET/MRI following hepatic radioembolization has the potential for predicting treatment outcome and, in turn, improving patient care. The positron decay branching ratio, however, is very small (32 ppm), yielding images with poor statistics even when therapy doses are used. Our purpose is to find PET reconstruction parameters that maximize the PET recovery coefficients and minimize noise. Methods: An initial 7.5 GBq of Y-90 chloride solution was used to fill an ACR phantom for measurements with a PET/MRI scanner (Siemens Biograph mMR). Four hot cylinders and a warm background activity volume of the phantom were filled with a 10:1 ratio. Phantom attenuation maps were derived from scaled CT images of the phantom and included the MR phased array coil. The phantom was imaged at six time points between 7.5–1.0 GBq total activity over a period of eight days. PET images were reconstructed via OP-OSEM with 21 subsets and varying iteration number (1–5), post-reconstruction filter size (5–10 mm), and either absolute or relative scatter correction. Recovery coefficients, SNR, and noise were measured as well as total activity in the phantom. Results: For the 120 different reconstructions, recovery coefficients ranged from 0.1–0.6 and improved with increasing iteration number and reduced post-reconstruction filter size. SNR, however, improved substantially with lower iteration numbers and larger post-reconstruction filters. From the phantom data, we found that performing 2 iterations, 21 subsets, and applying a 5 mm Gaussian post-reconstruction filter provided optimal recovery coefficients at a moderate noise level for a wide range of activity levels. Conclusion: The choice of reconstruction parameters for Y-90 PET images greatly influences both the accuracy of measurements and image quality. We have found reconstruction parameters that provide optimal recovery coefficients with minimized noise. Future work will include the effects

  7. An efficient algorithm for MR image reconstruction and compression

    International Nuclear Information System (INIS)

    Wang, Hang; Rosenfeld, D.; Braun, M.; Yan, Hong

    1992-01-01

    In magnetic resonance imaging (MRI), the original data are sampled in the spatial frequency domain. The sampled data thus constitute a set of discrete Fourier transform (DFT) coefficients. The image is usually reconstructed by taking inverse DFT. The image data may then be efficiently compressed using the discrete cosine transform (DCT). A method of using DCT to treat the sampled data is presented which combines two procedures, image reconstruction and data compression. This method may be particularly useful in medical picture archiving and communication systems where both image reconstruction and compression are important issues. 11 refs., 3 figs

  8. TREE STEM RECONSTRUCTION USING VERTICAL FISHEYE IMAGES: A PRELIMINARY STUDY

    Directory of Open Access Journals (Sweden)

    A. Berveglieri

    2016-06-01

    Full Text Available A preliminary study was conducted to assess a tree stem reconstruction technique with panoramic images taken with fisheye lenses. The concept is similar to the Structure from Motion (SfM technique, but the acquisition and data preparation rely on fisheye cameras to generate a vertical image sequence with height variations of the camera station. Each vertical image is rectified to four vertical planes, producing horizontal lateral views. The stems in the lateral view are rectified to the same scale in the image sequence to facilitate image matching. Using bundle adjustment, the stems are reconstructed, enabling later measurement and extraction of several attributes. The 3D reconstruction was performed with the proposed technique and compared with SfM. The preliminary results showed that the stems were correctly reconstructed by using the lateral virtual images generated from the vertical fisheye images and with the advantage of using fewer images and taken from one single station.

  9. Superiority of CT imaging reconstruction on Linux OS

    International Nuclear Information System (INIS)

    Lin Shaochun; Yan Xufeng; Wu Tengfang; Luo Xiaomei; Cai Huasong

    2010-01-01

    Objective: To compare the speed of CT reconstruction using the Linux and Windows OS. Methods: Shepp-Logan head phantom in different pixel size was projected to obtain the sinogram by using the inverse Fourier transformation, filtered back projection and Radon transformation on both Linux and Windows OS. Results: CT image reconstruction using the Linux operating system was significantly better and more efficient than Windows. Conclusion: CT image reconstruction using the Linux operating system is more efficient. (authors)

  10. Accelerated median root prior reconstruction for pinhole single-photon emission tomography (SPET)

    Energy Technology Data Exchange (ETDEWEB)

    Sohlberg, Antti [Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, PO Box 1777 FIN-70211, Kuopio (Finland); Ruotsalainen, Ulla [Institute of Signal Processing, DMI, Tampere University of Technology, PO Box 553 FIN-33101, Tampere (Finland); Watabe, Hiroshi [National Cardiovascular Center Research Institute, 5-7-1 Fujisihro-dai, Suita City, Osaka 565-8565 (Japan); Iida, Hidehiro [National Cardiovascular Center Research Institute, 5-7-1 Fujisihro-dai, Suita City, Osaka 565-8565 (Japan); Kuikka, Jyrki T [Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, PO Box 1777 FIN-70211, Kuopio (Finland)

    2003-07-07

    Pinhole collimation can be used to improve spatial resolution in SPET. However, the resolution improvement is achieved at the cost of reduced sensitivity, which leads to projection images with poor statistics. Images reconstructed from these projections using the maximum likelihood expectation maximization (ML-EM) algorithms, which have been used to reduce the artefacts generated by the filtered backprojection (FBP) based reconstruction, suffer from noise/bias trade-off: noise contaminates the images at high iteration numbers, whereas early abortion of the algorithm produces images that are excessively smooth and biased towards the initial estimate of the algorithm. To limit the noise accumulation we propose the use of the pinhole median root prior (PH-MRP) reconstruction algorithm. MRP is a Bayesian reconstruction method that has already been used in PET imaging and shown to possess good noise reduction and edge preservation properties. In this study the PH-MRP algorithm was accelerated with the ordered subsets (OS) procedure and compared to the FBP, OS-EM and conventional Bayesian reconstruction methods in terms of noise reduction, quantitative accuracy, edge preservation and visual quality. The results showed that the accelerated PH-MRP algorithm was very robust. It provided visually pleasing images with lower noise level than the FBP or OS-EM and with smaller bias and sharper edges than the conventional Bayesian methods.

  11. 3D Reconstruction of NMR Images by LabVIEW

    Directory of Open Access Journals (Sweden)

    Peter IZAK

    2007-01-01

    Full Text Available This paper introduces the experiment of 3D reconstruction NMR images via virtual instrumentation - LabVIEW. The main idea is based on marching cubes algorithm and image processing implemented by module of Vision assistant. The two dimensional images shot by the magnetic resonance device provide information about the surface properties of human body. There is implemented algorithm which can be used for 3D reconstruction of magnetic resonance images in biomedical application.

  12. Reconstruction of Optical Thickness from Hoffman Modulation Contrast Images

    DEFF Research Database (Denmark)

    Olsen, Niels Holm; Sporring, Jon; Nielsen, Mads

    2003-01-01

    Hoffman microscopy imaging systems are part of numerous fertility clinics world-wide. We discuss the physics of the Hoffman imaging system from optical thickness to image intensity, implement a simple, yet fast, reconstruction algorithm using Fast Fourier Transformation and discuss the usability...... of the method on a number of cells from a human embryo. Novelty is identifying the non-linearity of a typical Hoffman imaging system, and the application of Fourier Transformation to reconstruct the optical thickness....

  13. Reconstruction of Clear-PEM data with STIR

    CERN Document Server

    Martins, M V; Rodrigues, P; Trindade, A; Oliveira, N; Correia, M; Cordeiro, H; Ferreira, N C; Varela, J; Almeida, P

    2006-01-01

    The Clear-PEM scanner is a device based on planar detectors that is currently under development within the Crystal Clear Collaboration, at CERN. The basis for 3D image reconstruction in Clear-PEM is the software for tomographic image reconstruction (STIR). STIR is an open source object-oriented library that efficiently deals with the 3D positron emission tomography data sets. This library was originally designed for the traditional cylindrical scanners. In order to make its use compatible with planar scanner data, new functionalities were introduced into the library's framework. In this work, Monte Carlo simulations of the Clear-PEM scanner acquisitions were used as input for image reconstruction with the 3D OSEM algorithm available in STIR. The results presented indicate that dual plate PEM data can be accurately reconstructed using the enhanced STIR framework.

  14. 3D reconstruction based on light field images

    Science.gov (United States)

    Zhu, Dong; Wu, Chunhong; Liu, Yunluo; Fu, Dongmei

    2018-04-01

    This paper proposed a method of reconstructing three-dimensional (3D) scene from two light field images capture by Lytro illium. The work was carried out by first extracting the sub-aperture images from light field images and using the scale-invariant feature transform (SIFT) for feature registration on the selected sub-aperture images. Structure from motion (SFM) algorithm is further used on the registration completed sub-aperture images to reconstruct the three-dimensional scene. 3D sparse point cloud was obtained in the end. The method shows that the 3D reconstruction can be implemented by only two light field camera captures, rather than at least a dozen times captures by traditional cameras. This can effectively solve the time-consuming, laborious issues for 3D reconstruction based on traditional digital cameras, to achieve a more rapid, convenient and accurate reconstruction.

  15. Reconstructed Image Spatial Resolution of Multiple Coincidences Compton Imager

    Science.gov (United States)

    Andreyev, Andriy; Sitek, Arkadiusz; Celler, Anna

    2010-02-01

    We study the multiple coincidences Compton imager (MCCI) which is based on a simultaneous acquisition of several photons emitted in cascade from a single nuclear decay. Theoretically, this technique should provide a major improvement in localization of a single radioactive source as compared to a standard Compton camera. In this work, we investigated the performance and limitations of MCCI using Monte Carlo computer simulations. Spatial resolutions of the reconstructed point source have been studied as a function of the MCCI parameters, including geometrical dimensions and detector characteristics such as materials, energy and spatial resolutions.

  16. Low dose reconstruction algorithm for differential phase contrast imaging.

    Science.gov (United States)

    Wang, Zhentian; Huang, Zhifeng; Zhang, Li; Chen, Zhiqiang; Kang, Kejun; Yin, Hongxia; Wang, Zhenchang; Marco, Stampanoni

    2011-01-01

    Differential phase contrast imaging computed tomography (DPCI-CT) is a novel x-ray inspection method to reconstruct the distribution of refraction index rather than the attenuation coefficient in weakly absorbing samples. In this paper, we propose an iterative reconstruction algorithm for DPCI-CT which benefits from the new compressed sensing theory. We first realize a differential algebraic reconstruction technique (DART) by discretizing the projection process of the differential phase contrast imaging into a linear partial derivative matrix. In this way the compressed sensing reconstruction problem of DPCI reconstruction can be transformed to a resolved problem in the transmission imaging CT. Our algorithm has the potential to reconstruct the refraction index distribution of the sample from highly undersampled projection data. Thus it can significantly reduce the dose and inspection time. The proposed algorithm has been validated by numerical simulations and actual experiments.

  17. Longitudinal and transverse digital image reconstruction with a tomographic scanner

    International Nuclear Information System (INIS)

    Pickens, D.R.; Price, R.R.; Erickson, J.J.; Patton, J.A.; Partain, C.L.; Rollo, F.D.

    1981-01-01

    A Siemens Gammasonics PHO/CON-192 Multiplane Imager is interfaced to a digital computer for the purpose of performing tomographic reconstructions from the data collected during a single scan. Data from the two moving gamma cameras as well as camera position information are sent to the computer by an interface designed in the authors' laboratory. Backprojection reconstruction is implemented by the computer. Longitudinal images in whole-body format as well as smaller formats are reconstructed for up to six planes simultaneously from the list mode data. Transverse reconstructions are demonstrated for 201 T1 myocardial scans. Post-reconstruction deconvolution processing to remove the blur artifact (characteristic of focal plane tomography) is applied to a multiplane phantom. Digital data acquisition of data and reconstruction of images are practical, and can extend the usefulness of the machine when compared with the film output (author)

  18. Gadgetron: An Open Source Framework for Medical Image Reconstruction

    DEFF Research Database (Denmark)

    Hansen, Michael Schacht; Sørensen, Thomas Sangild

    2013-01-01

    This work presents a new open source framework for medical image reconstruction called the “Gadgetron.” The framework implements a flexible system for creating streaming data processing pipelines where data pass through a series of modules or “Gadgets” from raw data to reconstructed images...... with a set of dedicated toolboxes in shared libraries for medical image reconstruction. This includes generic toolboxes for data-parallel (e.g., GPU-based) execution of compute-intensive components. The basic framework architecture is independent of medical imaging modality, but this article focuses on its...

  19. Reconstruction CT imaging of the hypopharynx and the larynx

    International Nuclear Information System (INIS)

    Okuno, Tetsuji; Fujimura, Akiko; Murakami, Yasushi; Shiga, Hayao

    1986-01-01

    The multiplanar reconstruction CT imaging of the hypopharynx and the larynx was performed on a total of 20 cases: 8 with laryngeal carcinomas, 6 with hypopharyngeal carcinomas, 4 with vocal cord paralyses due to various causes, 1 with laryngeal amyloidosis, 1 with inflammatory granuloma of the hypopharynx. Coronal, segittal, and parasagittal reconstruction images were obtained from either 1 or 2 mm overlapping axial scans with 4 or 5 mm slice thickness (3 cases) using 5 sec scan times during queit breathing. In 15 cases with coronal reconstruction imaging, the anatomical derangements of the laryngopharyngeal structures especially along the undersurface of the true vocal cord to the false cord level, the lateral wall of the pyriform sinus, and the paraglottic space were demonstrated more clearly than the axial CT imaging. In 5 cases with sagittal reconstruction imaging, the vertical extension of the lesions through the anterior commisure was more clearly depicted than the axial CT imaging. In 8 cases with parasagittal reconstruction imaging, which is along the vocal fold or across the aryepiglottic fold, pathological changes along the aryepiglottic fold, the arytenoid-corniculate cartilage complex, and the tip of the pyriform sinus were more clearly demonstrated than the axial CT imaging. In determining the feasibility of conservation surgery of the larynx and the hypopharynx, reconstruction CT imaging is recommended as the diagnostic procedure of a choice, which would supplement the findings of the routine axial CT imaging. (author)

  20. Ultra-Fast Image Reconstruction of Tomosynthesis Mammography Using GPU.

    Science.gov (United States)

    Arefan, D; Talebpour, A; Ahmadinejhad, N; Kamali Asl, A

    2015-06-01

    Digital Breast Tomosynthesis (DBT) is a technology that creates three dimensional (3D) images of breast tissue. Tomosynthesis mammography detects lesions that are not detectable with other imaging systems. If image reconstruction time is in the order of seconds, we can use Tomosynthesis systems to perform Tomosynthesis-guided Interventional procedures. This research has been designed to study ultra-fast image reconstruction technique for Tomosynthesis Mammography systems using Graphics Processing Unit (GPU). At first, projections of Tomosynthesis mammography have been simulated. In order to produce Tomosynthesis projections, it has been designed a 3D breast phantom from empirical data. It is based on MRI data in its natural form. Then, projections have been created from 3D breast phantom. The image reconstruction algorithm based on FBP was programmed with C++ language in two methods using central processing unit (CPU) card and the Graphics Processing Unit (GPU). It calculated the time of image reconstruction in two kinds of programming (using CPU and GPU).

  1. Optimization of the alpha image reconstruction. An iterative CT-image reconstruction with well-defined image quality metrics

    International Nuclear Information System (INIS)

    Lebedev, Sergej; Sawall, Stefan; Knaup, Michael; Kachelriess, Marc

    2017-01-01

    Optimization of the AIR-algorithm for improved convergence and performance. TThe AIR method is an iterative algorithm for CT image reconstruction. As a result of its linearity with respect to the basis images, the AIR algorithm possesses well defined, regular image quality metrics, e.g. point spread function (PSF) or modulation transfer function (MTF), unlike other iterative reconstruction algorithms. The AIR algorithm computes weighting images α to blend between a set of basis images that preferably have mutually exclusive properties, e.g. high spatial resolution or low noise. The optimized algorithm uses an approach that alternates between the optimization of rawdata fidelity using an OSSART like update and regularization using gradient descent, as opposed to the initially proposed AIR using a straightforward gradient descent implementation. A regularization strength for a given task is chosen by formulating a requirement for the noise reduction and checking whether it is fulfilled for different regularization strengths, while monitoring the spatial resolution using the voxel-wise defined modulation transfer function for the AIR image. The optimized algorithm computes similar images in a shorter time compared to the initial gradient descent implementation of AIR. The result can be influenced by multiple parameters that can be narrowed down to a relatively simple framework to compute high quality images. The AIR images, for instance, can have at least a 50% lower noise level compared to the sharpest basis image, while the spatial resolution is mostly maintained. The optimization improves performance by a factor of 6, while maintaining image quality. Furthermore, it was demonstrated that the spatial resolution for AIR can be determined using regular image quality metrics, given smooth weighting images. This is not possible for other iterative reconstructions as a result of their non linearity. A simple set of parameters for the algorithm is discussed that provides

  2. Optimization of the alpha image reconstruction. An iterative CT-image reconstruction with well-defined image quality metrics

    Energy Technology Data Exchange (ETDEWEB)

    Lebedev, Sergej; Sawall, Stefan; Knaup, Michael; Kachelriess, Marc [German Cancer Research Center, Heidelberg (Germany).

    2017-10-01

    Optimization of the AIR-algorithm for improved convergence and performance. TThe AIR method is an iterative algorithm for CT image reconstruction. As a result of its linearity with respect to the basis images, the AIR algorithm possesses well defined, regular image quality metrics, e.g. point spread function (PSF) or modulation transfer function (MTF), unlike other iterative reconstruction algorithms. The AIR algorithm computes weighting images α to blend between a set of basis images that preferably have mutually exclusive properties, e.g. high spatial resolution or low noise. The optimized algorithm uses an approach that alternates between the optimization of rawdata fidelity using an OSSART like update and regularization using gradient descent, as opposed to the initially proposed AIR using a straightforward gradient descent implementation. A regularization strength for a given task is chosen by formulating a requirement for the noise reduction and checking whether it is fulfilled for different regularization strengths, while monitoring the spatial resolution using the voxel-wise defined modulation transfer function for the AIR image. The optimized algorithm computes similar images in a shorter time compared to the initial gradient descent implementation of AIR. The result can be influenced by multiple parameters that can be narrowed down to a relatively simple framework to compute high quality images. The AIR images, for instance, can have at least a 50% lower noise level compared to the sharpest basis image, while the spatial resolution is mostly maintained. The optimization improves performance by a factor of 6, while maintaining image quality. Furthermore, it was demonstrated that the spatial resolution for AIR can be determined using regular image quality metrics, given smooth weighting images. This is not possible for other iterative reconstructions as a result of their non linearity. A simple set of parameters for the algorithm is discussed that provides

  3. Direct reconstruction of parametric images for brain PET with event-by-event motion correction: evaluation in two tracers across count levels

    Science.gov (United States)

    Germino, Mary; Gallezot, Jean-Dominque; Yan, Jianhua; Carson, Richard E.

    2017-07-01

    Parametric images for dynamic positron emission tomography (PET) are typically generated by an indirect method, i.e. reconstructing a time series of emission images, then fitting a kinetic model to each voxel time activity curve. Alternatively, ‘direct reconstruction’, incorporates the kinetic model into the reconstruction algorithm itself, directly producing parametric images from projection data. Direct reconstruction has been shown to achieve parametric images with lower standard error than the indirect method. Here, we present direct reconstruction for brain PET using event-by-event motion correction of list-mode data, applied to two tracers. Event-by-event motion correction was implemented for direct reconstruction in the Parametric Motion-compensation OSEM List-mode Algorithm for Resolution-recovery reconstruction. The direct implementation was tested on simulated and human datasets with tracers [11C]AFM (serotonin transporter) and [11C]UCB-J (synaptic density), which follow the 1-tissue compartment model. Rigid head motion was tracked with the Vicra system. Parametric images of K 1 and distribution volume (V T  =  K 1/k 2) were compared to those generated by the indirect method by regional coefficient of variation (CoV). Performance across count levels was assessed using sub-sampled datasets. For simulated and real datasets at high counts, the two methods estimated K 1 and V T with comparable accuracy. At lower count levels, the direct method was substantially more robust to outliers than the indirect method. Compared to the indirect method, direct reconstruction reduced regional K 1 CoV by 35-48% (simulated dataset), 39-43% ([11C]AFM dataset) and 30-36% ([11C]UCB-J dataset) across count levels (averaged over regions at matched iteration); V T CoV was reduced by 51-58%, 54-60% and 30-46%, respectively. Motion correction played an important role in the dataset with larger motion: correction increased regional V T by 51% on average in the [11C

  4. Reconstruction of a ring applicator using CT imaging: impact of the reconstruction method and applicator orientation

    DEFF Research Database (Denmark)

    Hellebust, Taran Paulsen; Tanderup, Kari; Bergstrand, Eva Stabell

    2007-01-01

    in multiplanar reconstructed images (MPR) and (3) library plans, using pre-defined applicator geometry (LIB). The doses to the lead pellets were calculated. The relative standard deviation (SD) for all reconstruction methods was less than 3.7% in the dose points. The relative SD for the LIB method...

  5. Simbol-X Formation Flight and Image Reconstruction

    Science.gov (United States)

    Civitani, M.; Djalal, S.; Le Duigou, J. M.; La Marle, O.; Chipaux, R.

    2009-05-01

    Simbol-X is the first operational mission relying on two satellites flying in formation. The dynamics of the telescope, due to the formation flight concept, raises a variety of problematic, like image reconstruction, that can be better evaluated via a simulation tools. We present here the first results obtained with Simulos, simulation tool aimed to study the relative spacecrafts navigation and the weight of the different parameters in image reconstruction and telescope performance evaluation. The simulation relies on attitude and formation flight sensors models, formation flight dynamics and control, mirror model and focal plane model, while the image reconstruction is based on the Line of Sight (LOS) concept.

  6. Radionuclide imaging with coded apertures and three-dimensional image reconstruction from focal-plane tomography

    International Nuclear Information System (INIS)

    Chang, L.T.

    1976-05-01

    Two techniques for radionuclide imaging and reconstruction have been studied;; both are used for improvement of depth resolution. The first technique is called coded aperture imaging, which is a technique of tomographic imaging. The second technique is a special 3-D image reconstruction method which is introduced as an improvement to the so called focal-plane tomography

  7. Simultaneous maximum a posteriori longitudinal PET image reconstruction

    Science.gov (United States)

    Ellis, Sam; Reader, Andrew J.

    2017-09-01

    Positron emission tomography (PET) is frequently used to monitor functional changes that occur over extended time scales, for example in longitudinal oncology PET protocols that include routine clinical follow-up scans to assess the efficacy of a course of treatment. In these contexts PET datasets are currently reconstructed into images using single-dataset reconstruction methods. Inspired by recently proposed joint PET-MR reconstruction methods, we propose to reconstruct longitudinal datasets simultaneously by using a joint penalty term in order to exploit the high degree of similarity between longitudinal images. We achieved this by penalising voxel-wise differences between pairs of longitudinal PET images in a one-step-late maximum a posteriori (MAP) fashion, resulting in the MAP simultaneous longitudinal reconstruction (SLR) method. The proposed method reduced reconstruction errors and visually improved images relative to standard maximum likelihood expectation-maximisation (ML-EM) in simulated 2D longitudinal brain tumour scans. In reconstructions of split real 3D data with inserted simulated tumours, noise across images reconstructed with MAP-SLR was reduced to levels equivalent to doubling the number of detected counts when using ML-EM. Furthermore, quantification of tumour activities was largely preserved over a variety of longitudinal tumour changes, including changes in size and activity, with larger changes inducing larger biases relative to standard ML-EM reconstructions. Similar improvements were observed for a range of counts levels, demonstrating the robustness of the method when used with a single penalty strength. The results suggest that longitudinal regularisation is a simple but effective method of improving reconstructed PET images without using resolution degrading priors.

  8. Surface Reconstruction and Image Enhancement via $L^1$-Minimization

    KAUST Repository

    Dobrev, Veselin

    2010-01-01

    A surface reconstruction technique based on minimization of the total variation of the gradient is introduced. Convergence of the method is established, and an interior-point algorithm solving the associated linear programming problem is introduced. The reconstruction algorithm is illustrated on various test cases including natural and urban terrain data, and enhancement oflow-resolution or aliased images. Copyright © by SIAM.

  9. Fast implementations of reconstruction-based scatter compensation in fully 3D SPECT image reconstruction

    International Nuclear Information System (INIS)

    Kadrmas, Dan J.; Karimi, Seemeen S.; Frey, Eric C.; Tsui, Benjamin M.W.

    1998-01-01

    Accurate scatter compensation in SPECT can be performed by modelling the scatter response function during the reconstruction process. This method is called reconstruction-based scatter compensation (RBSC). It has been shown that RBSC has a number of advantages over other methods of compensating for scatter, but using RBSC for fully 3D compensation has resulted in prohibitively long reconstruction times. In this work we propose two new methods that can be used in conjunction with existing methods to achieve marked reductions in RBSC reconstruction times. The first method, coarse-grid scatter modelling, significantly accelerates the scatter model by exploiting the fact that scatter is dominated by low-frequency information. The second method, intermittent RBSC, further accelerates the reconstruction process by limiting the number of iterations during which scatter is modelled. The fast implementations were evaluated using a Monte Carlo simulated experiment of the 3D MCAT phantom with 99m Tc tracer, and also using experimentally acquired data with 201 Tl tracer. Results indicated that these fast methods can reconstruct, with fully 3D compensation, images very similar to those obtained using standard RBSC methods, and in reconstruction times that are an order of magnitude shorter. Using these methods, fully 3D iterative reconstruction with RBSC can be performed well within the realm of clinically realistic times (under 10 minutes for 64x64x24 image reconstruction). (author)

  10. Reconstruction of a ring applicator using CT imaging: impact of the reconstruction method and applicator orientation

    International Nuclear Information System (INIS)

    Hellebust, Taran Paulsen; Tanderup, Kari; Bergstrand, Eva Stabell; Knutsen, Bjoern Helge; Roeislien, Jo; Olsen, Dag Rune

    2007-01-01

    The purpose of this study is to investigate whether the method of applicator reconstruction and/or the applicator orientation influence the dose calculation to points around the applicator for brachytherapy of cervical cancer with CT-based treatment planning. A phantom, containing a fixed ring applicator set and six lead pellets representing dose points, was used. The phantom was CT scanned with the ring applicator at four different angles related to the image plane. In each scan the applicator was reconstructed by three methods: (1) direct reconstruction in each image (DR) (2) reconstruction in multiplanar reconstructed images (MPR) and (3) library plans, using pre-defined applicator geometry (LIB). The doses to the lead pellets were calculated. The relative standard deviation (SD) for all reconstruction methods was less than 3.7% in the dose points. The relative SD for the LIB method was significantly lower (p < 0.05) than for the DR and MPR methods for all but two points. All applicator orientations had similar dose calculation reproducibility. Using library plans for applicator reconstruction gives the most reproducible dose calculation. However, with restrictive guidelines for applicator reconstruction the uncertainties for all methods are low compared to other factors influencing the accuracy of brachytherapy

  11. Compressively sampled MR image reconstruction using generalized thresholding iterative algorithm

    Science.gov (United States)

    Elahi, Sana; kaleem, Muhammad; Omer, Hammad

    2018-01-01

    Compressed sensing (CS) is an emerging area of interest in Magnetic Resonance Imaging (MRI). CS is used for the reconstruction of the images from a very limited number of samples in k-space. This significantly reduces the MRI data acquisition time. One important requirement for signal recovery in CS is the use of an appropriate non-linear reconstruction algorithm. It is a challenging task to choose a reconstruction algorithm that would accurately reconstruct the MR images from the under-sampled k-space data. Various algorithms have been used to solve the system of non-linear equations for better image quality and reconstruction speed in CS. In the recent past, iterative soft thresholding algorithm (ISTA) has been introduced in CS-MRI. This algorithm directly cancels the incoherent artifacts produced because of the undersampling in k -space. This paper introduces an improved iterative algorithm based on p -thresholding technique for CS-MRI image reconstruction. The use of p -thresholding function promotes sparsity in the image which is a key factor for CS based image reconstruction. The p -thresholding based iterative algorithm is a modification of ISTA, and minimizes non-convex functions. It has been shown that the proposed p -thresholding iterative algorithm can be used effectively to recover fully sampled image from the under-sampled data in MRI. The performance of the proposed method is verified using simulated and actual MRI data taken at St. Mary's Hospital, London. The quality of the reconstructed images is measured in terms of peak signal-to-noise ratio (PSNR), artifact power (AP), and structural similarity index measure (SSIM). The proposed approach shows improved performance when compared to other iterative algorithms based on log thresholding, soft thresholding and hard thresholding techniques at different reduction factors.

  12. Algorithms for Reconstruction of Undersampled Atomic Force Microscopy Images Supplementary Material

    DEFF Research Database (Denmark)

    2017-01-01

    Two Jupyter Notebooks showcasing reconstructions of undersampled atomic force microscopy images. The reconstructions were obtained using a variety of interpolation and reconstruction methods.......Two Jupyter Notebooks showcasing reconstructions of undersampled atomic force microscopy images. The reconstructions were obtained using a variety of interpolation and reconstruction methods....

  13. A Kalman filter technique applied for medical image reconstruction

    International Nuclear Information System (INIS)

    Goliaei, S.; Ghorshi, S.; Manzuri, M. T.; Mortazavi, M.

    2011-01-01

    Medical images contain information about vital organic tissues inside of human body and are widely used for diagnoses of disease or for surgical purposes. Image reconstruction is essential for medical images for some applications such as suppression of noise or de-blurring the image in order to provide images with better quality and contrast. Due to vital rule of image reconstruction in medical sciences the corresponding algorithms with better efficiency and higher speed is desirable. Most algorithms in image reconstruction are operated on frequency domain such as the most popular one known as filtered back projection. In this paper we introduce a Kalman filter technique which is operated in time domain for medical image reconstruction. Results indicated that as the number of projection increases in both normal collected ray sum and the collected ray sum corrupted by noise the quality of reconstructed image becomes better in terms of contract and transparency. It is also seen that as the number of projection increases the error index decreases.

  14. CT Image Reconstruction in a Low Dimensional Manifold

    OpenAIRE

    Cong, Wenxiang; Wang, Ge; Yang, Qingsong; Hsieh, Jiang; Li, Jia; Lai, Rongjie

    2017-01-01

    Regularization methods are commonly used in X-ray CT image reconstruction. Different regularization methods reflect the characterization of different prior knowledge of images. In a recent work, a new regularization method called a low-dimensional manifold model (LDMM) is investigated to characterize the low-dimensional patch manifold structure of natural images, where the manifold dimensionality characterizes structural information of an image. In this paper, we propose a CT image reconstruc...

  15. Optimization of the reconstruction parameters in [123I]FP-CIT SPECT

    Science.gov (United States)

    Niñerola-Baizán, Aida; Gallego, Judith; Cot, Albert; Aguiar, Pablo; Lomeña, Francisco; Pavía, Javier; Ros, Domènec

    2018-04-01

    The aim of this work was to obtain a set of parameters to be applied in [123I]FP-CIT SPECT reconstruction in order to minimize the error between standardized and true values of the specific uptake ratio (SUR) in dopaminergic neurotransmission SPECT studies. To this end, Monte Carlo simulation was used to generate a database of 1380 projection data-sets from 23 subjects, including normal cases and a variety of pathologies. Studies were reconstructed using filtered back projection (FBP) with attenuation correction and ordered subset expectation maximization (OSEM) with correction for different degradations (attenuation, scatter and PSF). Reconstruction parameters to be optimized were the cut-off frequency of a 2D Butterworth pre-filter in FBP, and the number of iterations and the full width at Half maximum of a 3D Gaussian post-filter in OSEM. Reconstructed images were quantified using regions of interest (ROIs) derived from Magnetic Resonance scans and from the Automated Anatomical Labeling map. Results were standardized by applying a simple linear regression line obtained from the entire patient dataset. Our findings show that we can obtain a set of optimal parameters for each reconstruction strategy. The accuracy of the standardized SUR increases when the reconstruction method includes more corrections. The use of generic ROIs instead of subject-specific ROIs adds significant inaccuracies. Thus, after reconstruction with OSEM and correction for all degradations, subject-specific ROIs led to errors between standardized and true SUR values in the range [‑0.5, +0.5] in 87% and 92% of the cases for caudate and putamen, respectively. These percentages dropped to 75% and 88% when the generic ROIs were used.

  16. A study of reconstruction accuracy for a cardiac SPECT system with multi-segmental collimation

    International Nuclear Information System (INIS)

    Yu, D.C.; Chang, W.; Pan, T.S.

    1996-01-01

    To improve the geometric efficiency of cardiac SPECT imaging, we have previously proposed to use a ring geometry and a multi-segmental collimation. The proposed collimation consists of multiple parallel collimators with most of the segments focused on a small central region, where the patient heart should be positioned. This scheme provides an significantly increased detection efficiency for the central region, but at the expense of reduced efficiency for the surrounding background. We have used computer simulations to evaluate the implication of this scheme on the accuracy of the reconstructed cardiac images. Two imaging situations were simulated, one with the heart well placed in the center, the other with the heart shifted outward and partially outside the central region; a neighboring high uptake liver was also simulated. The images were reconstructed with ML-EM and OS-EM methods using a complete attenuation map. The results indicate the deviation caused by truncation is not significant and is not strongly dependent on the activity of the liver when the heart is well positioned within the central region. The distribution of activity in the myocardium reconstructed with ML-EM or OS-EM is not sensitive to the noisy projections sampled from the background. When the heart is positioned improperly, the image reconstructed from the hybrid emission (a combination of high-count projections through the central region and low-count background projections) can restore the activity for the myocardium with increased noise variances in the section outside the central region

  17. Time-of-flight PET image reconstruction using origin ensembles

    Science.gov (United States)

    Wülker, Christian; Sitek, Arkadiusz; Prevrhal, Sven

    2015-03-01

    The origin ensemble (OE) algorithm is a novel statistical method for minimum-mean-square-error (MMSE) reconstruction of emission tomography data. This method allows one to perform reconstruction entirely in the image domain, i.e. without the use of forward and backprojection operations. We have investigated the OE algorithm in the context of list-mode (LM) time-of-flight (TOF) PET reconstruction. In this paper, we provide a general introduction to MMSE reconstruction, and a statistically rigorous derivation of the OE algorithm. We show how to efficiently incorporate TOF information into the reconstruction process, and how to correct for random coincidences and scattered events. To examine the feasibility of LM-TOF MMSE reconstruction with the OE algorithm, we applied MMSE-OE and standard maximum-likelihood expectation-maximization (ML-EM) reconstruction to LM-TOF phantom data with a count number typically registered in clinical PET examinations. We analyzed the convergence behavior of the OE algorithm, and compared reconstruction time and image quality to that of the EM algorithm. In summary, during the reconstruction process, MMSE-OE contrast recovery (CRV) remained approximately the same, while background variability (BV) gradually decreased with an increasing number of OE iterations. The final MMSE-OE images exhibited lower BV and a slightly lower CRV than the corresponding ML-EM images. The reconstruction time of the OE algorithm was approximately 1.3 times longer. At the same time, the OE algorithm can inherently provide a comprehensive statistical characterization of the acquired data. This characterization can be utilized for further data processing, e.g. in kinetic analysis and image registration, making the OE algorithm a promising approach in a variety of applications.

  18. A study of transverse image reconstruction with digital subtraction angiography

    International Nuclear Information System (INIS)

    Sakamoto, Kiyoshi; Kotoura, Noriko; Terasawa, Yuuji; Oda, Masahiko; Gotou, Hiroshi; Nasada, Toshiya; Tanooka, Masao

    1995-01-01

    For digital subtraction angiography (DSA) with C-type equipment, it is possible to radiate an X-ray during rotation and to collect data at different angular settings. We tried to reconstruct transverse image from data obtained by scanning DSA images at different angular settings. 88 projection data were obtained by rotating the object at 180deg during radiation. Reconstruction was made using the convolution method with pixel value distribution for each projection. Similarly, the image quality of the reconstructed images were compared with the unsubtracted and subtracted ones. In case a part object was outside the calculating region, artifacts were generally produced. However, the artifacts were reduced by subtracting the background from the image. In addition, the cupping phenomenon caused by beam hardening was relaxed and high-quality imaging could be achieved. This method will become even more effective, if we will use it with selective angiography in which the limited area is enhanced. (author)

  19. Super-Resolution Image Reconstruction Applied to Medical Ultrasound

    Science.gov (United States)

    Ellis, Michael

    Ultrasound is the preferred imaging modality for many diagnostic applications due to its real-time image reconstruction and low cost. Nonetheless, conventional ultrasound is not used in many applications because of limited spatial resolution and soft tissue contrast. Most commercial ultrasound systems reconstruct images using a simple delay-and-sum architecture on receive, which is fast and robust but does not utilize all information available in the raw data. Recently, more sophisticated image reconstruction methods have been developed that make use of far more information in the raw data to improve resolution and contrast. One such method is the Time-Domain Optimized Near-Field Estimator (TONE), which employs a maximum a priori estimation to solve a highly underdetermined problem, given a well-defined system model. TONE has been shown to significantly improve both the contrast and resolution of ultrasound images when compared to conventional methods. However, TONE's lack of robustness to variations from the system model and extremely high computational cost hinder it from being readily adopted in clinical scanners. This dissertation aims to reduce the impact of TONE's shortcomings, transforming it from an academic construct to a clinically viable image reconstruction algorithm. By altering the system model from a collection of individual hypothetical scatterers to a collection of weighted, diffuse regions, dTONE is able to achieve much greater robustness to modeling errors. A method for efficient parallelization of dTONE is presented that reduces reconstruction time by more than an order of magnitude with little loss in image fidelity. An alternative reconstruction algorithm, called qTONE, is also developed and is able to reduce reconstruction times by another two orders of magnitude while simultaneously improving image contrast. Each of these methods for improving TONE are presented, their limitations are explored, and all are used in concert to reconstruct in

  20. Robust sparse image reconstruction of radio interferometric observations with PURIFY

    Science.gov (United States)

    Pratley, Luke; McEwen, Jason D.; d'Avezac, Mayeul; Carrillo, Rafael E.; Onose, Alexandru; Wiaux, Yves

    2018-01-01

    Next-generation radio interferometers, such as the Square Kilometre Array, will revolutionize our understanding of the Universe through their unprecedented sensitivity and resolution. However, to realize these goals significant challenges in image and data processing need to be overcome. The standard methods in radio interferometry for reconstructing images, such as CLEAN, have served the community well over the last few decades and have survived largely because they are pragmatic. However, they produce reconstructed interferometric images that are limited in quality and scalability for big data. In this work, we apply and evaluate alternative interferometric reconstruction methods that make use of state-of-the-art sparse image reconstruction algorithms motivated by compressive sensing, which have been implemented in the PURIFY software package. In particular, we implement and apply the proximal alternating direction method of multipliers algorithm presented in a recent article. First, we assess the impact of the interpolation kernel used to perform gridding and degridding on sparse image reconstruction. We find that the Kaiser-Bessel interpolation kernel performs as well as prolate spheroidal wave functions while providing a computational saving and an analytic form. Secondly, we apply PURIFY to real interferometric observations from the Very Large Array and the Australia Telescope Compact Array and find that images recovered by PURIFY are of higher quality than those recovered by CLEAN. Thirdly, we discuss how PURIFY reconstructions exhibit additional advantages over those recovered by CLEAN. The latest version of PURIFY, with developments presented in this work, is made publicly available.

  1. Region of interest evaluation of SPECT image reconstruction methods using a realistic brain phantom

    International Nuclear Information System (INIS)

    Xia, Weishi; Glick, S.J.; Soares, E.J.

    1996-01-01

    A realistic numerical brain phantom, developed by Zubal et al, was used for a region-of-interest evaluation of the accuracy and noise variance of the following SPECT reconstruction methods: (1) Maximum-Likelihood reconstruction using the Expectation-Maximization (ML-EM) algorithm; (2) an EM algorithm using ordered-subsets (OS-EM); (3) a re-scaled block iterative EM algorithm (RBI-EM); and (4) a filtered backprojection algorithm that uses a combination of the Bellini method for attenuation compensation and an iterative spatial blurring correction method using the frequency-distance principle (FDP). The Zubal phantom was made from segmented MRI slices of the brain, so that neuro-anatomical structures are well defined and indexed. Small regions-of-interest (ROIs) from the white matter, grey matter in the center of the brain and grey matter from the peripheral area of the brain were selected for the evaluation. Photon attenuation and distance-dependent collimator blurring were modeled. Multiple independent noise realizations were generated for two different count levels. The simulation study showed that the ROI bias measured for the EM-based algorithms decreased as the iteration number increased, and that the OS-EM and RBI-EM algorithms (16 and 64 subsets were used) achieved the equivalent accuracy of the ML-EM algorithm at about the same noise variance, with much fewer number of iterations. The Bellini-FDP restoration algorithm converged fast and required less computation per iteration. The ML-EM algorithm had a slightly better ROI bias vs. variance trade-off than the other algorithms

  2. Application of Super-Resolution Image Reconstruction to Digital Holography

    Directory of Open Access Journals (Sweden)

    Zhang Shuqun

    2006-01-01

    Full Text Available We describe a new application of super-resolution image reconstruction to digital holography which is a technique for three-dimensional information recording and reconstruction. Digital holography has suffered from the low resolution of CCD sensors, which significantly limits the size of objects that can be recorded. The existing solution to this problem is to use optics to bandlimit the object to be recorded, which can cause the loss of details. Here super-resolution image reconstruction is proposed to be applied in enhancing the spatial resolution of digital holograms. By introducing a global camera translation before sampling, a high-resolution hologram can be reconstructed from a set of undersampled hologram images. This permits the recording of larger objects and reduces the distance between the object and the hologram. Practical results from real and simulated holograms are presented to demonstrate the feasibility of the proposed technique.

  3. Fingerprint image reconstruction for swipe sensor using Predictive Overlap Method

    Directory of Open Access Journals (Sweden)

    Mardiansyah Ahmad Zafrullah

    2018-01-01

    Full Text Available Swipe sensor is one of many biometric authentication sensor types that widely applied to embedded devices. The sensor produces an overlap on every pixel block of the image, so the picture requires a reconstruction process before heading to the feature extraction process. Conventional reconstruction methods require extensive computation, causing difficult to apply to embedded devices that have limited computing process. In this paper, image reconstruction is proposed using predictive overlap method, which determines the image block shift from the previous set of change data. The experiments were performed using 36 images generated by a swipe sensor with 128 x 8 pixels size of the area, where each image has an overlap in each block. The results reveal computation can increase up to 86.44% compared with conventional methods, with accuracy decreasing to 0.008% in average.

  4. Quantitative reconstruction from a single diffraction-enhanced image

    International Nuclear Information System (INIS)

    Paganin, D.M.; Lewis, R.A.; Kitchen, M.

    2003-01-01

    Full text: We develop an algorithm for using a single diffraction-enhanced image (DEI) to obtain a quantitative reconstruction of the projected thickness of a single-material sample which is embedded within a substrate of approximately constant thickness. This algorithm is used to quantitatively map inclusions in a breast phantom, from a single synchrotron DEI image. In particular, the reconstructed images quantitatively represent the projected thickness in the bulk of the sample, in contrast to DEI images which greatly emphasise sharp edges (high spatial frequencies). In the context of an ultimate aim of improved methods for breast cancer detection, the reconstructions are potentially of greater diagnostic value compared to the DEI data. Lastly, we point out that the methods of analysis presented here are also applicable to the quantitative analysis of differential interference contrast (DIC) images

  5. Matrix-based image reconstruction methods for tomography

    International Nuclear Information System (INIS)

    Llacer, J.; Meng, J.D.

    1984-10-01

    Matrix methods of image reconstruction have not been used, in general, because of the large size of practical matrices, ill condition upon inversion and the success of Fourier-based techniques. An exception is the work that has been done at the Lawrence Berkeley Laboratory for imaging with accelerated radioactive ions. An extension of that work into more general imaging problems shows that, with a correct formulation of the problem, positron tomography with ring geometries results in well behaved matrices which can be used for image reconstruction with no distortion of the point response in the field of view and flexibility in the design of the instrument. Maximum Likelihood Estimator methods of reconstruction, which use the system matrices tailored to specific instruments and do not need matrix inversion, are shown to result in good preliminary images. A parallel processing computer structure based on multiple inexpensive microprocessors is proposed as a system to implement the matrix-MLE methods. 14 references, 7 figures

  6. Three dimensional image reconstruction in the Fourier domain

    International Nuclear Information System (INIS)

    Stearns, C.W.; Chesler, D.A.; Brownell, G.L.

    1987-01-01

    Filtered backprojection reconstruction algorithms are based upon the relationship between the Fourier transform of the imaged object and the Fourier transforms of its projections. A new reconstruction algorithm has been developed which performs the image assembly operation in Fourier space, rather than in image space by backprojection. This represents a significant decrease in the number of operations required to assemble the image. The new Fourier domain algorithm has resolution comparable to the filtered backprojection algorithm, and, after correction by a pointwise multiplication, demonstrates proper recovery throughout image space. Although originally intended for three-dimensional imaging applications, the Fourier domain algorithm can also be developed for two-dimensional imaging applications such as planar positron imaging systems

  7. Photoelectron holography with improved image reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Matsushita, Tomohiro, E-mail: matusita@spring8.or.j [Japan Synchrotron Radiation Research Institute (JASRI), SPring-8, 1-1-1 Kouto, Sayo-cho, Sayo-gun Hyogo 679-5198 (Japan); Matsui, Fumihiko; Daimon, Hiroshi [Nara Institute of Science and Technology (NAIST), 8916-5 Takayama, Ikoma, Nara 630-0192 (Japan); Hayashi, Kouichi [Institute for Materials Research, Tohoku University, Sendai 980-8577 (Japan)

    2010-05-15

    Electron holography is a type of atomic structural analysis, and it has unique features such as element selectivity and the ability to analyze the structure around an impurity in a crystal. In this paper, we introduce the measurement system, electron holograms, a theory for the recording process of an electron hologram, and a theory for the reconstruction algorithm. We describe photoelectron holograms, Auger electron holograms, and the inverse mode of an electron hologram. The reconstruction algorithm, scattering pattern extraction algorithm (SPEA), the SPEA with maximum entropy method (SPEA-MEM), and SPEA-MEM with translational operation are also described.

  8. Photoelectron holography with improved image reconstruction

    International Nuclear Information System (INIS)

    Matsushita, Tomohiro; Matsui, Fumihiko; Daimon, Hiroshi; Hayashi, Kouichi

    2010-01-01

    Electron holography is a type of atomic structural analysis, and it has unique features such as element selectivity and the ability to analyze the structure around an impurity in a crystal. In this paper, we introduce the measurement system, electron holograms, a theory for the recording process of an electron hologram, and a theory for the reconstruction algorithm. We describe photoelectron holograms, Auger electron holograms, and the inverse mode of an electron hologram. The reconstruction algorithm, scattering pattern extraction algorithm (SPEA), the SPEA with maximum entropy method (SPEA-MEM), and SPEA-MEM with translational operation are also described.

  9. Fast Dictionary-Based Reconstruction for Diffusion Spectrum Imaging

    Science.gov (United States)

    Bilgic, Berkin; Chatnuntawech, Itthi; Setsompop, Kawin; Cauley, Stephen F.; Yendiki, Anastasia; Wald, Lawrence L.; Adalsteinsson, Elfar

    2015-01-01

    Diffusion Spectrum Imaging (DSI) reveals detailed local diffusion properties at the expense of substantially long imaging times. It is possible to accelerate acquisition by undersampling in q-space, followed by image reconstruction that exploits prior knowledge on the diffusion probability density functions (pdfs). Previously proposed methods impose this prior in the form of sparsity under wavelet and total variation (TV) transforms, or under adaptive dictionaries that are trained on example datasets to maximize the sparsity of the representation. These compressed sensing (CS) methods require full-brain processing times on the order of hours using Matlab running on a workstation. This work presents two dictionary-based reconstruction techniques that use analytical solutions, and are two orders of magnitude faster than the previously proposed dictionary-based CS approach. The first method generates a dictionary from the training data using Principal Component Analysis (PCA), and performs the reconstruction in the PCA space. The second proposed method applies reconstruction using pseudoinverse with Tikhonov regularization with respect to a dictionary. This dictionary can either be obtained using the K-SVD algorithm, or it can simply be the training dataset of pdfs without any training. All of the proposed methods achieve reconstruction times on the order of seconds per imaging slice, and have reconstruction quality comparable to that of dictionary-based CS algorithm. PMID:23846466

  10. Fast dictionary-based reconstruction for diffusion spectrum imaging.

    Science.gov (United States)

    Bilgic, Berkin; Chatnuntawech, Itthi; Setsompop, Kawin; Cauley, Stephen F; Yendiki, Anastasia; Wald, Lawrence L; Adalsteinsson, Elfar

    2013-11-01

    Diffusion spectrum imaging reveals detailed local diffusion properties at the expense of substantially long imaging times. It is possible to accelerate acquisition by undersampling in q-space, followed by image reconstruction that exploits prior knowledge on the diffusion probability density functions (pdfs). Previously proposed methods impose this prior in the form of sparsity under wavelet and total variation transforms, or under adaptive dictionaries that are trained on example datasets to maximize the sparsity of the representation. These compressed sensing (CS) methods require full-brain processing times on the order of hours using MATLAB running on a workstation. This work presents two dictionary-based reconstruction techniques that use analytical solutions, and are two orders of magnitude faster than the previously proposed dictionary-based CS approach. The first method generates a dictionary from the training data using principal component analysis (PCA), and performs the reconstruction in the PCA space. The second proposed method applies reconstruction using pseudoinverse with Tikhonov regularization with respect to a dictionary. This dictionary can either be obtained using the K-SVD algorithm, or it can simply be the training dataset of pdfs without any training. All of the proposed methods achieve reconstruction times on the order of seconds per imaging slice, and have reconstruction quality comparable to that of dictionary-based CS algorithm.

  11. Convergence of iterative image reconstruction algorithms for Digital Breast Tomosynthesis

    DEFF Research Database (Denmark)

    Sidky, Emil; Jørgensen, Jakob Heide; Pan, Xiaochuan

    2012-01-01

    Most iterative image reconstruction algorithms are based on some form of optimization, such as minimization of a data-fidelity term plus an image regularizing penalty term. While achieving the solution of these optimization problems may not directly be clinically relevant, accurate optimization s...

  12. Analytic 3D image reconstruction using all detected events

    International Nuclear Information System (INIS)

    Kinahan, P.E.; Rogers, J.G.

    1988-11-01

    We present the results of testing a previously presented algorithm for three-dimensional image reconstruction that uses all gamma-ray coincidence events detected by a PET volume-imaging scanner. By using two iterations of an analytic filter-backprojection method, the algorithm is not constrained by the requirement of a spatially invariant detector point spread function, which limits normal analytic techniques. Removing this constraint allows the incorporation of all detected events, regardless of orientation, which improves the statistical quality of the final reconstructed image

  13. Three-dimensional image reconstruction. I. Determination of pattern orientation

    International Nuclear Information System (INIS)

    Blankenbecler, Richard

    2004-01-01

    The problem of determining the Euler angles of a randomly oriented three-dimensional (3D) object from its 2D Fraunhofer diffraction patterns is discussed. This problem arises in the reconstruction of a positive semidefinite 3D object using oversampling techniques. In such a problem, the data consist of a measured set of magnitudes from 2D tomographic images of the object at several unknown orientations. After the orientation angles are determined, the object itself can then be reconstructed by a variety of methods using oversampling, the magnitude data from the 2D images, physical constraints on the image, and then iteration to determine the phases

  14. Few-view image reconstruction with dual dictionaries

    International Nuclear Information System (INIS)

    Lu Yang; Zhao Jun; Wang Ge

    2012-01-01

    In this paper, we formulate the problem of computed tomography (CT) under sparsity and few-view constraints, and propose a novel algorithm for image reconstruction from few-view data utilizing the simultaneous algebraic reconstruction technique (SART) coupled with dictionary learning, sparse representation and total variation (TV) minimization on two interconnected levels. The main feature of our algorithm is the use of two dictionaries: a transitional dictionary for atom matching and a global dictionary for image updating. The atoms in the global and transitional dictionaries represent the image patches from high-quality and low-quality CT images, respectively. Experiments with simulated and real projections were performed to evaluate and validate the proposed algorithm. The results reconstructed using the proposed approach are significantly better than those using either SART or SART–TV. (paper)

  15. Bayesian image reconstruction for improving detection performance of muon tomography.

    Science.gov (United States)

    Wang, Guobao; Schultz, Larry J; Qi, Jinyi

    2009-05-01

    Muon tomography is a novel technology that is being developed for detecting high-Z materials in vehicles or cargo containers. Maximum likelihood methods have been developed for reconstructing the scattering density image from muon measurements. However, the instability of maximum likelihood estimation often results in noisy images and low detectability of high-Z targets. In this paper, we propose using regularization to improve the image quality of muon tomography. We formulate the muon reconstruction problem in a Bayesian framework by introducing a prior distribution on scattering density images. An iterative shrinkage algorithm is derived to maximize the log posterior distribution. At each iteration, the algorithm obtains the maximum a posteriori update by shrinking an unregularized maximum likelihood update. Inverse quadratic shrinkage functions are derived for generalized Laplacian priors and inverse cubic shrinkage functions are derived for generalized Gaussian priors. Receiver operating characteristic studies using simulated data demonstrate that the Bayesian reconstruction can greatly improve the detection performance of muon tomography.

  16. Evaluation of aortocoronary bypass graft patency by reconstructed CT image

    International Nuclear Information System (INIS)

    Kawakita, Seizaburo; Koide, Takashi; Saito, Yoshio; Yamamoto, Tadao; Iwasaki, Tadaaki

    1982-01-01

    Ten patients were examined in the period of three months from January to March 1981. The patients were operated from 1 month to 7 years before CT. A bypass to the left anterior descending artery (LAD) was grafted in 10 cases, 2 to the right coronary artery (RCA), 4 to an obtuse marginal artery (OM), and 1 to a diagonal artery. Image reconstruction was performed in 10 cases by using an image analytical computer Evaluskop. Appropriate planes for reconstruction were selected by trial and error methods upon observation of CT images. When gained picture of a graft course coincided with surgical records or angiography, the work of building images was concluded. On cross section, grafts to LAD were visualized in all 10 cases: 9 in the entire course and 1 in a proximal part of the graft. Two to RCA, 4 to OM and 1 to a diagonal were also successfully visualized. Reconstruction of graft images succeeded in 9 grafts of 6 cases. The course of a graft could be pursued from the proximal to the distal end adjacent to the cardiac chamber. The picture of a bypass to LAD was visualized in 6 of 10 grafts. Two bypass to RCA could be depicted, and 1 to OM was also found. However 3 to OM and 1 to a diagonal failed to be visualized throughout their courses in reconstructed images. I think that the causes of faillure mainly depended upon the course of the graft. When a graft was running arc-like surrounding the heart chamber, it was very difficult to depict its entire length in reconstructed images, though the graft could be detected in cross sections. These preliminary studies indicated that reconstruction of CT images had some benefits for the pursuit of graft courses. (J.P.N.)

  17. A neural network image reconstruction technique for electrical impedance tomography

    International Nuclear Information System (INIS)

    Adler, A.; Guardo, R.

    1994-01-01

    Reconstruction of Images in Electrical Impedance Tomography requires the solution of a nonlinear inverse problem on noisy data. This problem is typically ill-conditioned and requires either simplifying assumptions or regularization based on a priori knowledge. This paper presents a reconstruction algorithm using neural network techniques which calculates a linear approximation of the inverse problem directly from finite element simulations of the forward problem. This inverse is adapted to the geometry of the medium and the signal-to-noise ratio (SNR) used during network training. Results show good conductivity reconstruction where measurement SNR is similar to the training conditions. The advantages of this method are its conceptual simplicity and ease of implementation, and the ability to control the compromise between the noise performance and resolution of the image reconstruction

  18. Biologically inspired EM image alignment and neural reconstruction.

    Science.gov (United States)

    Knowles-Barley, Seymour; Butcher, Nancy J; Meinertzhagen, Ian A; Armstrong, J Douglas

    2011-08-15

    Three-dimensional reconstruction of consecutive serial-section transmission electron microscopy (ssTEM) images of neural tissue currently requires many hours of manual tracing and annotation. Several computational techniques have already been applied to ssTEM images to facilitate 3D reconstruction and ease this burden. Here, we present an alternative computational approach for ssTEM image analysis. We have used biologically inspired receptive fields as a basis for a ridge detection algorithm to identify cell membranes, synaptic contacts and mitochondria. Detected line segments are used to improve alignment between consecutive images and we have joined small segments of membrane into cell surfaces using a dynamic programming algorithm similar to the Needleman-Wunsch and Smith-Waterman DNA sequence alignment procedures. A shortest path-based approach has been used to close edges and achieve image segmentation. Partial reconstructions were automatically generated and used as a basis for semi-automatic reconstruction of neural tissue. The accuracy of partial reconstructions was evaluated and 96% of membrane could be identified at the cost of 13% false positive detections. An open-source reference implementation is available in the Supplementary information. seymour.kb@ed.ac.uk; douglas.armstrong@ed.ac.uk Supplementary data are available at Bioinformatics online.

  19. Prospective regularization design in prior-image-based reconstruction

    International Nuclear Information System (INIS)

    Dang, Hao; Siewerdsen, Jeffrey H; Stayman, J Webster

    2015-01-01

    Prior-image-based reconstruction (PIBR) methods leveraging patient-specific anatomical information from previous imaging studies and/or sequences have demonstrated dramatic improvements in dose utilization and image quality for low-fidelity data. However, a proper balance of information from the prior images and information from the measurements is required (e.g. through careful tuning of regularization parameters). Inappropriate selection of reconstruction parameters can lead to detrimental effects including false structures and failure to improve image quality. Traditional methods based on heuristics are subject to error and sub-optimal solutions, while exhaustive searches require a large number of computationally intensive image reconstructions. In this work, we propose a novel method that prospectively estimates the optimal amount of prior image information for accurate admission of specific anatomical changes in PIBR without performing full image reconstructions. This method leverages an analytical approximation to the implicitly defined PIBR estimator, and introduces a predictive performance metric leveraging this analytical form and knowledge of a particular presumed anatomical change whose accurate reconstruction is sought. Additionally, since model-based PIBR approaches tend to be space-variant, a spatially varying prior image strength map is proposed to optimally admit changes everywhere in the image (eliminating the need to know change locations a priori). Studies were conducted in both an ellipse phantom and a realistic thorax phantom emulating a lung nodule surveillance scenario. The proposed method demonstrated accurate estimation of the optimal prior image strength while achieving a substantial computational speedup (about a factor of 20) compared to traditional exhaustive search. Moreover, the use of the proposed prior strength map in PIBR demonstrated accurate reconstruction of anatomical changes without foreknowledge of change locations in

  20. Image interface in Java for tomographic reconstruction in nuclear medicine

    International Nuclear Information System (INIS)

    Andrade, M.A.; Silva, A.M. Marques da

    2004-01-01

    The aim of this study is to implement a software for tomographic reconstruction of SPECT data from Nuclear Medicine with a flexible interface design, cross-platform, written in Java. Validation tests were performed based on SPECT simulated data. The results showed that the implemented algorithms and filters agree with the theoretical context. We intend to extend the system by implementing additional tomographic reconstruction techniques and Java threads, in order to provide simultaneously image processing. (author)

  1. Image Reconstruction For Bioluminescence Tomography From Partial Measurement

    OpenAIRE

    Jiang, M.; Zhou, T.; Cheng, J. T.; Cong, W. X.; Wang, Ge

    2007-01-01

    The bioluminescence tomography is a novel molecular imaging technology for small animal studies. Known reconstruction methods require the completely measured data on the external surface, although only partially measured data is available in practice. In this work, we formulate a mathematical model for BLT from partial data and generalize our previous results on the solution uniqueness to the partial data case. Then we extend two of our reconstruction methods for BLT to this case. The first m...

  2. Demosaicing and Superresolution for Color Filter Array via Residual Image Reconstruction and Sparse Representation

    OpenAIRE

    Sun, Guangling

    2012-01-01

    A framework of demosaicing and superresolution for color filter array (CFA) via residual image reconstruction and sparse representation is presented.Given the intermediate image produced by certain demosaicing and interpolation technique, a residual image between the final reconstruction image and the intermediate image is reconstructed using sparse representation.The final reconstruction image has richer edges and details than that of the intermediate image. Specifically, a generic dictionar...

  3. Reconstructing flaw image using dataset of full matrix capture technique

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Tae Hun; Kim, Yong Sik; Lee, Jeong Seok [KHNP Central Research Institute, Daejeon (Korea, Republic of)

    2017-02-15

    A conventional phased array ultrasonic system offers the ability to steer an ultrasonic beam by applying independent time delays of individual elements in the array and produce an ultrasonic image. In contrast, full matrix capture (FMC) is a data acquisition process that collects a complete matrix of A-scans from every possible independent transmit-receive combination in a phased array transducer and makes it possible to reconstruct various images that cannot be produced by conventional phased array with the post processing as well as images equivalent to a conventional phased array image. In this paper, a basic algorithm based on the LLL mode total focusing method (TFM) that can image crack type flaws is described. And this technique was applied to reconstruct flaw images from the FMC dataset obtained from the experiments and ultrasonic simulation.

  4. Image reconstruction in computerized tomography using the convolution method

    International Nuclear Information System (INIS)

    Oliveira Rebelo, A.M. de.

    1984-03-01

    In the present work an algoritin was derived, using the analytical convolution method (filtered back-projection) for two-dimensional or three-dimensional image reconstruction in computerized tomography applied to non-destructive testing and to the medical use. This mathematical model is based on the analytical Fourier transform method for image reconstruction. This model consists of a discontinuous system formed by an NxN array of cells (pixels). The attenuation in the object under study of a colimated gamma ray beam has been determined for various positions and incidence angles (projections) in terms of the interaction of the beam with the intercepted pixels. The contribution of each pixel to beam attenuation was determined using the weight function W ij which was used for simulated tests. Simulated tests using standard objects with attenuation coefficients in the range of 0,2 to 0,7 cm -1 were carried out using cell arrays of up to 25x25. One application was carried out in the medical area simulating image reconstruction of an arm phantom with attenuation coefficients in the range of 0,2 to 0,5 cm -1 using cell arrays of 41x41. The simulated results show that, in objects with a great number of interfaces and great variations of attenuation coefficients at these interfaces, a good reconstruction is obtained with the number of projections equal to the reconstruction matrix dimension. A good reconstruction is otherwise obtained with fewer projections. (author) [pt

  5. Isotope specific resolution recovery image reconstruction in high resolution PET imaging

    OpenAIRE

    Kotasidis Fotis A.; Kotasidis Fotis A.; Angelis Georgios I.; Anton-Rodriguez Jose; Matthews Julian C.; Reader Andrew J.; Reader Andrew J.; Zaidi Habib; Zaidi Habib; Zaidi Habib

    2014-01-01

    Purpose: Measuring and incorporating a scanner specific point spread function (PSF) within image reconstruction has been shown to improve spatial resolution in PET. However due to the short half life of clinically used isotopes other long lived isotopes not used in clinical practice are used to perform the PSF measurements. As such non optimal PSF models that do not correspond to those needed for the data to be reconstructed are used within resolution modeling (RM) image reconstruction usuall...

  6. 3D widefield light microscope image reconstruction without dyes

    Science.gov (United States)

    Larkin, S.; Larson, J.; Holmes, C.; Vaicik, M.; Turturro, M.; Jurkevich, A.; Sinha, S.; Ezashi, T.; Papavasiliou, G.; Brey, E.; Holmes, T.

    2015-03-01

    3D image reconstruction using light microscope modalities without exogenous contrast agents is proposed and investigated as an approach to produce 3D images of biological samples for live imaging applications. Multimodality and multispectral imaging, used in concert with this 3D optical sectioning approach is also proposed as a way to further produce contrast that could be specific to components in the sample. The methods avoid usage of contrast agents. Contrast agents, such as fluorescent or absorbing dyes, can be toxic to cells or alter cell behavior. Current modes of producing 3D image sets from a light microscope, such as 3D deconvolution algorithms and confocal microscopy generally require contrast agents. Zernike phase contrast (ZPC), transmitted light brightfield (TLB), darkfield microscopy and others can produce contrast without dyes. Some of these modalities have not previously benefitted from 3D image reconstruction algorithms, however. The 3D image reconstruction algorithm is based on an underlying physical model of scattering potential, expressed as the sample's 3D absorption and phase quantities. The algorithm is based upon optimizing an objective function - the I-divergence - while solving for the 3D absorption and phase quantities. Unlike typical deconvolution algorithms, each microscope modality, such as ZPC or TLB, produces two output image sets instead of one. Contrast in the displayed image and 3D renderings is further enabled by treating the multispectral/multimodal data as a feature set in a mathematical formulation that uses the principal component method of statistics.

  7. Reconstruction of CT images by the Bayes- back projection method

    CERN Document Server

    Haruyama, M; Takase, M; Tobita, H

    2002-01-01

    In the course of research on quantitative assay of non-destructive measurement of radioactive waste, the have developed a unique program based on the Bayesian theory for reconstruction of transmission computed tomography (TCT) image. The reconstruction of cross-section images in the CT technology usually employs the Filtered Back Projection method. The new imaging reconstruction program reported here is based on the Bayesian Back Projection method, and it has a function of iterative improvement images by every step of measurement. Namely, this method has the capability of prompt display of a cross-section image corresponding to each angled projection data from every measurement. Hence, it is possible to observe an improved cross-section view by reflecting each projection data in almost real time. From the basic theory of Baysian Back Projection method, it can be not only applied to CT types of 1st, 2nd, and 3rd generation. This reported deals with a reconstruction program of cross-section images in the CT of ...

  8. Ultra-Fast Image Reconstruction of Tomosynthesis Mammography Using GPU

    Directory of Open Access Journals (Sweden)

    Arefan D

    2015-06-01

    Full Text Available Digital Breast Tomosynthesis (DBT is a technology that creates three dimensional (3D images of breast tissue. Tomosynthesis mammography detects lesions that are not detectable with other imaging systems. If image reconstruction time is in the order of seconds, we can use Tomosynthesis systems to perform Tomosynthesis-guided Interventional procedures. This research has been designed to study ultra-fast image reconstruction technique for Tomosynthesis Mammography systems using Graphics Processing Unit (GPU. At first, projections of Tomosynthesis mammography have been simulated. In order to produce Tomosynthesis projections, it has been designed a 3D breast phantom from empirical data. It is based on MRI data in its natural form. Then, projections have been created from 3D breast phantom. The image reconstruction algorithm based on FBP was programmed with C++ language in two methods using central processing unit (CPU card and the Graphics Processing Unit (GPU. It calculated the time of image reconstruction in two kinds of programming (using CPU and GPU.

  9. Image reconstruction technique using projection data from neutron tomography system

    Directory of Open Access Journals (Sweden)

    Waleed Abd el Bar

    2015-12-01

    Full Text Available Neutron tomography is a very powerful technique for nondestructive evaluation of heavy industrial components as well as for soft hydrogenous materials enclosed in heavy metals which are usually difficult to image using X-rays. Due to the properties of the image acquisition system, the projection images are distorted by several artifacts, and these reduce the quality of the reconstruction. In order to eliminate these harmful effects the projection images should be corrected before reconstruction. This paper gives a description of a filter back projection (FBP technique, which is used for reconstruction of projected data obtained from transmission measurements by neutron tomography system We demonstrated the use of spatial Discrete Fourier Transform (DFT and the 2D Inverse DFT in the formulation of the method, and outlined the theory of reconstruction of a 2D neutron image from a sequence of 1D projections taken at different angles between 0 and π in MATLAB environment. Projections are generated by applying the Radon transform to the original image at different angles.

  10. Optical image reconstruction using DC data: simulations and experiments

    International Nuclear Information System (INIS)

    Huabei Jiang; Paulsen, K.D.; Oesterberg, U.L.

    1996-01-01

    In this paper, we explore optical image formation using a diffusion approximation of light propagation in tissue which is modelled with a finite-element method for optically heterogeneous media. We demonstrate successful image reconstruction based on absolute experimental DC data obtained with a continuous wave 633 nm He-Ne laser system and a 751 nm diode laser system in laboratory phantoms having two optically distinct regions. The experimental systems used exploit a tomographic type of data collection scheme that provides information from which a spatially variable optical property map is deduced. Reconstruction of scattering coefficient only and simultaneous reconstruction of both scattering and absorption profiles in tissue-like phantoms are obtained from measured and simulated data. Images with different contrast levels between the heterogeneity and the background are also reported and the results show that although it is possible to obtain qualitative visual information on the location and size of a heterogeneity, it may not be possible to quantitatively resolve contrast levels or optical properties using reconstructions from DC data only. Sensitivity of image reconstruction to noise in the measurement data is investigated through simulations. The application of boundary constraints has also been addressed. (author)

  11. Block Compressed Sensing of Images Using Adaptive Granular Reconstruction

    Directory of Open Access Journals (Sweden)

    Ran Li

    2016-01-01

    Full Text Available In the framework of block Compressed Sensing (CS, the reconstruction algorithm based on the Smoothed Projected Landweber (SPL iteration can achieve the better rate-distortion performance with a low computational complexity, especially for using the Principle Components Analysis (PCA to perform the adaptive hard-thresholding shrinkage. However, during learning the PCA matrix, it affects the reconstruction performance of Landweber iteration to neglect the stationary local structural characteristic of image. To solve the above problem, this paper firstly uses the Granular Computing (GrC to decompose an image into several granules depending on the structural features of patches. Then, we perform the PCA to learn the sparse representation basis corresponding to each granule. Finally, the hard-thresholding shrinkage is employed to remove the noises in patches. The patches in granule have the stationary local structural characteristic, so that our method can effectively improve the performance of hard-thresholding shrinkage. Experimental results indicate that the reconstructed image by the proposed algorithm has better objective quality when compared with several traditional ones. The edge and texture details in the reconstructed image are better preserved, which guarantees the better visual quality. Besides, our method has still a low computational complexity of reconstruction.

  12. Alpha image reconstruction (AIR): A new iterative CT image reconstruction approach using voxel-wise alpha blending

    International Nuclear Information System (INIS)

    Hofmann, Christian; Sawall, Stefan; Knaup, Michael; Kachelrieß, Marc

    2014-01-01

    Purpose: Iterative image reconstruction gains more and more interest in clinical routine, as it promises to reduce image noise (and thereby patient dose), to reduce artifacts, or to improve spatial resolution. Among vendors and researchers, however, there is no consensus of how to best achieve these aims. The general approach is to incorporatea priori knowledge into iterative image reconstruction, for example, by adding additional constraints to the cost function, which penalize variations between neighboring voxels. However, this approach to regularization in general poses a resolution noise trade-off because the stronger the regularization, and thus the noise reduction, the stronger the loss of spatial resolution and thus loss of anatomical detail. The authors propose a method which tries to improve this trade-off. The proposed reconstruction algorithm is called alpha image reconstruction (AIR). One starts with generating basis images, which emphasize certain desired image properties, like high resolution or low noise. The AIR algorithm reconstructs voxel-specific weighting coefficients that are applied to combine the basis images. By combining the desired properties of each basis image, one can generate an image with lower noise and maintained high contrast resolution thus improving the resolution noise trade-off. Methods: All simulations and reconstructions are performed in native fan-beam geometry. A water phantom with resolution bar patterns and low contrast disks is simulated. A filtered backprojection (FBP) reconstruction with a Ram-Lak kernel is used as a reference reconstruction. The results of AIR are compared against the FBP results and against a penalized weighted least squares reconstruction which uses total variation as regularization. The simulations are based on the geometry of the Siemens Somatom Definition Flash scanner. To quantitatively assess image quality, the authors analyze line profiles through resolution patterns to define a contrast

  13. Adaptive reconstructions for magnetic resonance imaging of moving organs

    International Nuclear Information System (INIS)

    Lohezic, Maelene

    2011-01-01

    Magnetic resonance imaging (MRI) is a valuable tool for the clinical diagnosis for brain imaging as well as cardiac and abdominal imaging. For instance, MRI is the only modality that enables the visualization and characterization myocardial edema. However, motion remains a challenging problem for cardiac MRI. Breathing as well as cardiac beating have to be carefully handled during patient examination. Moreover they limit the achievable temporal and spatial resolution of the images. In this work an approach that takes these physiological motions into account during image reconstruction process has been proposed. It allows performing cardiac examination while breathing freely. First, an iterative reconstruction algorithm, that compensates motion estimated from a motion model constrained by physiological signals, is applied to morphological cardiac imaging. A semi-automatic method for edema detection has been tested on reconstructed images. It has also been associated with an adaptive acquisition strategy which enables free-breathing end-systolic imaging. This reconstruction has then been extended to the assessment of transverse relaxation times T2, which is used for myocardial edema characterization. The proposed method, ARTEMIS, enables free-breathing T2 mapping without additional acquisition time. The proposed free breathing approaches take advantage of physiological signals to estimate the motion that occurs during MR acquisitions. Several solutions have been tested to measure this information. Among them, accelerometer-based external sensors allow local measurements at several locations. Another approach consists in the use of k-space based measurements, which are 'embedded' inside the MRI pulse sequence (navigator) and prevent from the requirement of additional recording hardware. Hence, several adaptive reconstruction algorithms were developed to obtain diagnostic information from free breathing acquisitions. These works allow performing efficient and accurate

  14. Improving parallel imaging by jointly reconstructing multi-contrast data.

    Science.gov (United States)

    Bilgic, Berkin; Kim, Tae Hyung; Liao, Congyu; Manhard, Mary Kate; Wald, Lawrence L; Haldar, Justin P; Setsompop, Kawin

    2018-08-01

    To develop parallel imaging techniques that simultaneously exploit coil sensitivity encoding, image phase prior information, similarities across multiple images, and complementary k-space sampling for highly accelerated data acquisition. We introduce joint virtual coil (JVC)-generalized autocalibrating partially parallel acquisitions (GRAPPA) to jointly reconstruct data acquired with different contrast preparations, and show its application in 2D, 3D, and simultaneous multi-slice (SMS) acquisitions. We extend the joint parallel imaging concept to exploit limited support and smooth phase constraints through Joint (J-) LORAKS formulation. J-LORAKS allows joint parallel imaging from limited autocalibration signal region, as well as permitting partial Fourier sampling and calibrationless reconstruction. We demonstrate highly accelerated 2D balanced steady-state free precession with phase cycling, SMS multi-echo spin echo, 3D multi-echo magnetization-prepared rapid gradient echo, and multi-echo gradient recalled echo acquisitions in vivo. Compared to conventional GRAPPA, proposed joint acquisition/reconstruction techniques provide more than 2-fold reduction in reconstruction error. JVC-GRAPPA takes advantage of additional spatial encoding from phase information and image similarity, and employs different sampling patterns across acquisitions. J-LORAKS achieves a more parsimonious low-rank representation of local k-space by considering multiple images as additional coils. Both approaches provide dramatic improvement in artifact and noise mitigation over conventional single-contrast parallel imaging reconstruction. Magn Reson Med 80:619-632, 2018. © 2018 International Society for Magnetic Resonance in Medicine. © 2018 International Society for Magnetic Resonance in Medicine.

  15. Filter and slice thickness selection in SPECT image reconstruction

    International Nuclear Information System (INIS)

    Ivanovic, M.; Weber, D.A.; Wilson, G.A.; O'Mara, R.E.

    1985-01-01

    The choice of filter and slice thickness in SPECT image reconstruction as function of activity and linear and angular sampling were investigated in phantom and patient imaging studies. Reconstructed transverse and longitudinal spatial resolution of the system were measured using a line source in a water filled phantom. Phantom studies included measurements of the Data Spectrum phantom; clinical studies included tomographic procedures in 40 patients undergoing imaging of the temporomandibular joint. Slices of the phantom and patient images were evaluated for spatial of the phantom and patient images were evaluated for spatial resolution, noise, and image quality. Major findings include; spatial resolution and image quality improve with increasing linear sampling frequencies over the range of 4-8 mm/p in the phantom images, best spatial resolution and image quality in clinical images were observed at a linear sampling frequency of 6mm/p, Shepp and Logan filter gives the best spatial resolution for phantom studies at the lowest linear sampling frequency; smoothed Shepp and Logan filter provides best quality images without loss of resolution at higher frequencies and, spatial resolution and image quality improve with increased angular sampling frequency in the phantom at 40 c/p but appear to be independent of angular sampling frequency at 400 c/p

  16. Image Reconstruction Algorithm For Electrical Capacitance Tomography (ECT)

    International Nuclear Information System (INIS)

    Arko

    2001-01-01

    ). Most image reconstruction algorithms for electrical capacitance tomography (ECT) use sensitivity maps as weighting factors. The computation is fast, involving a simple multiply-and- accumulate (MAC) operation, but the resulting image suffers from blurring due to the soft-field effect of the sensor. This paper presents a low cost iterative method employing proportional thresholding, which improves image quality dramatically. The strategy for implementation, computational cost, and achievable speed is examined when using a personal computer (PC) and Digital Signal Processor (DSP). For PC implementation, Watcom C++ 10.6 and Visual C++ 5.0 compilers were used. The experimental results are compared to the images reconstructed by commercially available software. The new algorithm improves the image quality significantly at a cost of a few iterations. This technique can be readily exploited for online applications

  17. Silhouette-based approach of 3D image reconstruction for automated image acquisition using robotic arm

    Science.gov (United States)

    Azhar, N.; Saad, W. H. M.; Manap, N. A.; Saad, N. M.; Syafeeza, A. R.

    2017-06-01

    This study presents the approach of 3D image reconstruction using an autonomous robotic arm for the image acquisition process. A low cost of the automated imaging platform is created using a pair of G15 servo motor connected in series to an Arduino UNO as a main microcontroller. Two sets of sequential images were obtained using different projection angle of the camera. The silhouette-based approach is used in this study for 3D reconstruction from the sequential images captured from several different angles of the object. Other than that, an analysis based on the effect of different number of sequential images on the accuracy of 3D model reconstruction was also carried out with a fixed projection angle of the camera. The effecting elements in the 3D reconstruction are discussed and the overall result of the analysis is concluded according to the prototype of imaging platform.

  18. Blockwise conjugate gradient methods for image reconstruction in volumetric CT.

    Science.gov (United States)

    Qiu, W; Titley-Peloquin, D; Soleimani, M

    2012-11-01

    Cone beam computed tomography (CBCT) enables volumetric image reconstruction from 2D projection data and plays an important role in image guided radiation therapy (IGRT). Filtered back projection is still the most frequently used algorithm in applications. The algorithm discretizes the scanning process (forward projection) into a system of linear equations, which must then be solved to recover images from measured projection data. The conjugate gradients (CG) algorithm and its variants can be used to solve (possibly regularized) linear systems of equations Ax=b and linear least squares problems minx∥b-Ax∥2, especially when the matrix A is very large and sparse. Their applications can be found in a general CT context, but in tomography problems (e.g. CBCT reconstruction) they have not widely been used. Hence, CBCT reconstruction using the CG-type algorithm LSQR was implemented and studied in this paper. In CBCT reconstruction, the main computational challenge is that the matrix A usually is very large, and storing it in full requires an amount of memory well beyond the reach of commodity computers. Because of these memory capacity constraints, only a small fraction of the weighting matrix A is typically used, leading to a poor reconstruction. In this paper, to overcome this difficulty, the matrix A is partitioned and stored blockwise, and blockwise matrix-vector multiplications are implemented within LSQR. This implementation allows us to use the full weighting matrix A for CBCT reconstruction without further enhancing computer standards. Tikhonov regularization can also be implemented in this fashion, and can produce significant improvement in the reconstructed images. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  19. Development of computed tomography system and image reconstruction algorithm

    International Nuclear Information System (INIS)

    Khairiah Yazid; Mohd Ashhar Khalid; Azaman Ahmad; Khairul Anuar Mohd Salleh; Ab Razak Hamzah

    2006-01-01

    Computed tomography is one of the most advanced and powerful nondestructive inspection techniques, which is currently used in many different industries. In several CT systems, detection has been by combination of an X-ray image intensifier and charge -coupled device (CCD) camera or by using line array detector. The recent development of X-ray flat panel detector has made fast CT imaging feasible and practical. Therefore this paper explained the arrangement of a new detection system which is using the existing high resolution (127 μm pixel size) flat panel detector in MINT and the image reconstruction technique developed. The aim of the project is to develop a prototype flat panel detector based CT imaging system for NDE. The prototype consisted of an X-ray tube, a flat panel detector system, a rotation table and a computer system to control the sample motion and image acquisition. Hence this project is divided to two major tasks, firstly to develop image reconstruction algorithm and secondly to integrate X-ray imaging components into one CT system. The image reconstruction algorithm using filtered back-projection method is developed and compared to other techniques. The MATLAB program is the tools used for the simulations and computations for this project. (Author)

  20. Dictionary Approaches to Image Compression and Reconstruction

    Science.gov (United States)

    Ziyad, Nigel A.; Gilmore, Erwin T.; Chouikha, Mohamed F.

    1998-01-01

    This paper proposes using a collection of parameterized waveforms, known as a dictionary, for the purpose of medical image compression. These waveforms, denoted as phi(sub gamma), are discrete time signals, where gamma represents the dictionary index. A dictionary with a collection of these waveforms is typically complete or overcomplete. Given such a dictionary, the goal is to obtain a representation image based on the dictionary. We examine the effectiveness of applying Basis Pursuit (BP), Best Orthogonal Basis (BOB), Matching Pursuits (MP), and the Method of Frames (MOF) methods for the compression of digitized radiological images with a wavelet-packet dictionary. The performance of these algorithms is studied for medical images with and without additive noise.

  1. System and method for three-dimensional image reconstruction using an absolute orientation sensor

    KAUST Repository

    Giancola, Silvio; Ghanem, Bernard; Schneider, Jens; Wonka, Peter

    2018-01-01

    A three-dimensional image reconstruction system includes an image capture device, an inertial measurement unit (IMU), and an image processor. The image capture device captures image data. The inertial measurement unit (IMU) is affixed to the image

  2. Joint model of motion and anatomy for PET image reconstruction

    International Nuclear Information System (INIS)

    Qiao Feng; Pan Tinsu; Clark, John W. Jr.; Mawlawi, Osama

    2007-01-01

    Anatomy-based positron emission tomography (PET) image enhancement techniques have been shown to have the potential for improving PET image quality. However, these techniques assume an accurate alignment between the anatomical and the functional images, which is not always valid when imaging the chest due to respiratory motion. In this article, we present a joint model of both motion and anatomical information by integrating a motion-incorporated PET imaging system model with an anatomy-based maximum a posteriori image reconstruction algorithm. The mismatched anatomical information due to motion can thus be effectively utilized through this joint model. A computer simulation and a phantom study were conducted to assess the efficacy of the joint model, whereby motion and anatomical information were either modeled separately or combined. The reconstructed images in each case were compared to corresponding reference images obtained using a quadratic image prior based maximum a posteriori reconstruction algorithm for quantitative accuracy. Results of these studies indicated that while modeling anatomical information or motion alone improved the PET image quantitation accuracy, a larger improvement in accuracy was achieved when using the joint model. In the computer simulation study and using similar image noise levels, the improvement in quantitation accuracy compared to the reference images was 5.3% and 19.8% when using anatomical or motion information alone, respectively, and 35.5% when using the joint model. In the phantom study, these results were 5.6%, 5.8%, and 19.8%, respectively. These results suggest that motion compensation is important in order to effectively utilize anatomical information in chest imaging using PET. The joint motion-anatomy model presented in this paper provides a promising solution to this problem

  3. Cryo-EM Structure Determination Using Segmented Helical Image Reconstruction.

    Science.gov (United States)

    Fromm, S A; Sachse, C

    2016-01-01

    Treating helices as single-particle-like segments followed by helical image reconstruction has become the method of choice for high-resolution structure determination of well-ordered helical viruses as well as flexible filaments. In this review, we will illustrate how the combination of latest hardware developments with optimized image processing routines have led to a series of near-atomic resolution structures of helical assemblies. Originally, the treatment of helices as a sequence of segments followed by Fourier-Bessel reconstruction revealed the potential to determine near-atomic resolution structures from helical specimens. In the meantime, real-space image processing of helices in a stack of single particles was developed and enabled the structure determination of specimens that resisted classical Fourier helical reconstruction and also facilitated high-resolution structure determination. Despite the progress in real-space analysis, the combination of Fourier and real-space processing is still commonly used to better estimate the symmetry parameters as the imposition of the correct helical symmetry is essential for high-resolution structure determination. Recent hardware advancement by the introduction of direct electron detectors has significantly enhanced the image quality and together with improved image processing procedures has made segmented helical reconstruction a very productive cryo-EM structure determination method. © 2016 Elsevier Inc. All rights reserved.

  4. CT image reconstruction system based on hardware implementation

    International Nuclear Information System (INIS)

    Silva, Hamilton P. da; Evseev, Ivan; Schelin, Hugo R.; Paschuk, Sergei A.; Milhoretto, Edney; Setti, Joao A.P.; Zibetti, Marcelo; Hormaza, Joel M.; Lopes, Ricardo T.

    2009-01-01

    Full text: The timing factor is very important for medical imaging systems, which can nowadays be synchronized by vital human signals, like heartbeats or breath. The use of hardware implemented devices in such a system has advantages considering the high speed of information treatment combined with arbitrary low cost on the market. This article refers to a hardware system which is based on electronic programmable logic called FPGA, model Cyclone II from ALTERA Corporation. The hardware was implemented on the UP3 ALTERA Kit. A partially connected neural network with unitary weights was programmed. The system was tested with 60 topographic projections, 100 points in each, of the Shepp and Logan phantom created by MATLAB. The main restriction was found to be the memory size available on the device: the dynamic range of reconstructed image was limited to 0 65535. Also, the normalization factor must be observed in order to do not saturate the image during the reconstruction and filtering process. The test shows a principal possibility to build CT image reconstruction systems for any reasonable amount of input data by arranging the parallel work of the hardware units like we have tested. However, further studies are necessary for better understanding of the error propagation from topographic projections to reconstructed image within the implemented method. (author)

  5. PET image reconstruction: mean, variance, and optimal minimax criterion

    International Nuclear Information System (INIS)

    Liu, Huafeng; Guo, Min; Gao, Fei; Shi, Pengcheng; Xue, Liying; Nie, Jing

    2015-01-01

    Given the noise nature of positron emission tomography (PET) measurements, it is critical to know the image quality and reliability as well as expected radioactivity map (mean image) for both qualitative interpretation and quantitative analysis. While existing efforts have often been devoted to providing only the reconstructed mean image, we present a unified framework for joint estimation of the mean and corresponding variance of the radioactivity map based on an efficient optimal min–max criterion. The proposed framework formulates the PET image reconstruction problem to be a transformation from system uncertainties to estimation errors, where the minimax criterion is adopted to minimize the estimation errors with possibly maximized system uncertainties. The estimation errors, in the form of a covariance matrix, express the measurement uncertainties in a complete way. The framework is then optimized by ∞-norm optimization and solved with the corresponding H ∞ filter. Unlike conventional statistical reconstruction algorithms, that rely on the statistical modeling methods of the measurement data or noise, the proposed joint estimation stands from the point of view of signal energies and can handle from imperfect statistical assumptions to even no a priori statistical assumptions. The performance and accuracy of reconstructed mean and variance images are validated using Monte Carlo simulations. Experiments on phantom scans with a small animal PET scanner and real patient scans are also conducted for assessment of clinical potential. (paper)

  6. Software for 3D diagnostic image reconstruction and analysis

    International Nuclear Information System (INIS)

    Taton, G.; Rokita, E.; Sierzega, M.; Klek, S.; Kulig, J.; Urbanik, A.

    2005-01-01

    Recent advances in computer technologies have opened new frontiers in medical diagnostics. Interesting possibilities are the use of three-dimensional (3D) imaging and the combination of images from different modalities. Software prepared in our laboratories devoted to 3D image reconstruction and analysis from computed tomography and ultrasonography is presented. In developing our software it was assumed that it should be applicable in standard medical practice, i.e. it should work effectively with a PC. An additional feature is the possibility of combining 3D images from different modalities. The reconstruction and data processing can be conducted using a standard PC, so low investment costs result in the introduction of advanced and useful diagnostic possibilities. The program was tested on a PC using DICOM data from computed tomography and TIFF files obtained from a 3D ultrasound system. The results of the anthropomorphic phantom and patient data were taken into consideration. A new approach was used to achieve spatial correlation of two independently obtained 3D images. The method relies on the use of four pairs of markers within the regions under consideration. The user selects the markers manually and the computer calculates the transformations necessary for coupling the images. The main software feature is the possibility of 3D image reconstruction from a series of two-dimensional (2D) images. The reconstructed 3D image can be: (1) viewed with the most popular methods of 3D image viewing, (2) filtered and processed to improve image quality, (3) analyzed quantitatively (geometrical measurements), and (4) coupled with another, independently acquired 3D image. The reconstructed and processed 3D image can be stored at every stage of image processing. The overall software performance was good considering the relatively low costs of the hardware used and the huge data sets processed. The program can be freely used and tested (source code and program available at

  7. Parametric image reconstruction using spectral analysis of PET projection data

    International Nuclear Information System (INIS)

    Meikle, Steven R.; Matthews, Julian C.; Cunningham, Vincent J.; Bailey, Dale L.; Livieratos, Lefteris; Jones, Terry; Price, Pat

    1998-01-01

    Spectral analysis is a general modelling approach that enables calculation of parametric images from reconstructed tracer kinetic data independent of an assumed compartmental structure. We investigated the validity of applying spectral analysis directly to projection data motivated by the advantages that: (i) the number of reconstructions is reduced by an order of magnitude and (ii) iterative reconstruction becomes practical which may improve signal-to-noise ratio (SNR). A dynamic software phantom with typical 2-[ 11 C]thymidine kinetics was used to compare projection-based and image-based methods and to assess bias-variance trade-offs using iterative expectation maximization (EM) reconstruction. We found that the two approaches are not exactly equivalent due to properties of the non-negative least-squares algorithm. However, the differences are small ( 1 and, to a lesser extent, VD). The optimal number of EM iterations was 15-30 with up to a two-fold improvement in SNR over filtered back projection. We conclude that projection-based spectral analysis with EM reconstruction yields accurate parametric images with high SNR and has potential application to a wide range of positron emission tomography ligands. (author)

  8. Generalized Fourier slice theorem for cone-beam image reconstruction.

    Science.gov (United States)

    Zhao, Shuang-Ren; Jiang, Dazong; Yang, Kevin; Yang, Kang

    2015-01-01

    The cone-beam reconstruction theory has been proposed by Kirillov in 1961, Tuy in 1983, Feldkamp in 1984, Smith in 1985, Pierre Grangeat in 1990. The Fourier slice theorem is proposed by Bracewell 1956, which leads to the Fourier image reconstruction method for parallel-beam geometry. The Fourier slice theorem is extended to fan-beam geometry by Zhao in 1993 and 1995. By combining the above mentioned cone-beam image reconstruction theory and the above mentioned Fourier slice theory of fan-beam geometry, the Fourier slice theorem in cone-beam geometry is proposed by Zhao 1995 in short conference publication. This article offers the details of the derivation and implementation of this Fourier slice theorem for cone-beam geometry. Especially the problem of the reconstruction from Fourier domain has been overcome, which is that the value of in the origin of Fourier space is 0/0. The 0/0 type of limit is proper handled. As examples, the implementation results for the single circle and two perpendicular circle source orbits are shown. In the cone-beam reconstruction if a interpolation process is considered, the number of the calculations for the generalized Fourier slice theorem algorithm is O(N^4), which is close to the filtered back-projection method, here N is the image size of 1-dimension. However the interpolation process can be avoid, in that case the number of the calculations is O(N5).

  9. TU-AB-BRA-04: Quantitative Radiomics: Sensitivity of PET Textural Features to Image Acquisition and Reconstruction Parameters Implies the Need for Standards

    International Nuclear Information System (INIS)

    Nyflot, MJ; Yang, F; Byrd, D; Bowen, SR; Sandison, GA; Kinahan, PE

    2015-01-01

    Purpose: Despite increased use of heterogeneity metrics for PET imaging, standards for metrics such as textural features have yet to be developed. We evaluated the quantitative variability caused by image acquisition and reconstruction parameters on PET textural features. Methods: PET images of the NEMA IQ phantom were simulated with realistic image acquisition noise. 35 features based on intensity histograms (IH), co-occurrence matrices (COM), neighborhood-difference matrices (NDM), and zone-size matrices (ZSM) were evaluated within lesions (13, 17, 22, 28, 33 mm diameter). Variability in metrics across 50 independent images was evaluated as percent difference from mean for three phantom girths (850, 1030, 1200 mm) and two OSEM reconstructions (2 iterations, 28 subsets, 5 mm FWHM filtration vs 6 iterations, 28 subsets, 8.6 mm FWHM filtration). Also, patient sample size to detect a clinical effect of 30% with Bonferroni-corrected α=0.001 and 95% power was estimated. Results: As a class, NDM features demonstrated greatest sensitivity in means (5–50% difference for medium girth and reconstruction comparisons and 10–100% for large girth comparisons). Some IH features (standard deviation, energy, entropy) had variability below 10% for all sensitivity studies, while others (kurtosis, skewness) had variability above 30%. COM and ZSM features had complex sensitivities; correlation, energy, entropy (COM) and zone percentage, short-zone emphasis, zone-size non-uniformity (ZSM) had variability less than 5% while other metrics had differences up to 30%. Trends were similar for sample size estimation; for example, coarseness, contrast, and strength required 12, 38, and 52 patients to detect a 30% effect for the small girth case but 38, 88, and 128 patients in the large girth case. Conclusion: The sensitivity of PET textural features to image acquisition and reconstruction parameters is large and feature-dependent. Standards are needed to ensure that prospective trials

  10. TU-AB-BRA-04: Quantitative Radiomics: Sensitivity of PET Textural Features to Image Acquisition and Reconstruction Parameters Implies the Need for Standards

    Energy Technology Data Exchange (ETDEWEB)

    Nyflot, MJ; Yang, F; Byrd, D; Bowen, SR; Sandison, GA; Kinahan, PE [University of Washington, Seattle, WA (United States)

    2015-06-15

    Purpose: Despite increased use of heterogeneity metrics for PET imaging, standards for metrics such as textural features have yet to be developed. We evaluated the quantitative variability caused by image acquisition and reconstruction parameters on PET textural features. Methods: PET images of the NEMA IQ phantom were simulated with realistic image acquisition noise. 35 features based on intensity histograms (IH), co-occurrence matrices (COM), neighborhood-difference matrices (NDM), and zone-size matrices (ZSM) were evaluated within lesions (13, 17, 22, 28, 33 mm diameter). Variability in metrics across 50 independent images was evaluated as percent difference from mean for three phantom girths (850, 1030, 1200 mm) and two OSEM reconstructions (2 iterations, 28 subsets, 5 mm FWHM filtration vs 6 iterations, 28 subsets, 8.6 mm FWHM filtration). Also, patient sample size to detect a clinical effect of 30% with Bonferroni-corrected α=0.001 and 95% power was estimated. Results: As a class, NDM features demonstrated greatest sensitivity in means (5–50% difference for medium girth and reconstruction comparisons and 10–100% for large girth comparisons). Some IH features (standard deviation, energy, entropy) had variability below 10% for all sensitivity studies, while others (kurtosis, skewness) had variability above 30%. COM and ZSM features had complex sensitivities; correlation, energy, entropy (COM) and zone percentage, short-zone emphasis, zone-size non-uniformity (ZSM) had variability less than 5% while other metrics had differences up to 30%. Trends were similar for sample size estimation; for example, coarseness, contrast, and strength required 12, 38, and 52 patients to detect a 30% effect for the small girth case but 38, 88, and 128 patients in the large girth case. Conclusion: The sensitivity of PET textural features to image acquisition and reconstruction parameters is large and feature-dependent. Standards are needed to ensure that prospective trials

  11. Dynamic PET Image reconstruction for parametric imaging using the HYPR kernel method

    Science.gov (United States)

    Spencer, Benjamin; Qi, Jinyi; Badawi, Ramsey D.; Wang, Guobao

    2017-03-01

    Dynamic PET image reconstruction is a challenging problem because of the ill-conditioned nature of PET and the lowcounting statistics resulted from short time-frames in dynamic imaging. The kernel method for image reconstruction has been developed to improve image reconstruction of low-count PET data by incorporating prior information derived from high-count composite data. In contrast to most of the existing regularization-based methods, the kernel method embeds image prior information in the forward projection model and does not require an explicit regularization term in the reconstruction formula. Inspired by the existing highly constrained back-projection (HYPR) algorithm for dynamic PET image denoising, we propose in this work a new type of kernel that is simpler to implement and further improves the kernel-based dynamic PET image reconstruction. Our evaluation study using a physical phantom scan with synthetic FDG tracer kinetics has demonstrated that the new HYPR kernel-based reconstruction can achieve a better region-of-interest (ROI) bias versus standard deviation trade-off for dynamic PET parametric imaging than the post-reconstruction HYPR denoising method and the previously used nonlocal-means kernel.

  12. The influence of image reconstruction algorithms on linear thorax EIT image analysis of ventilation

    International Nuclear Information System (INIS)

    Zhao, Zhanqi; Möller, Knut; Frerichs, Inéz; Pulletz, Sven; Müller-Lisse, Ullrich

    2014-01-01

    Analysis methods of electrical impedance tomography (EIT) images based on different reconstruction algorithms were examined. EIT measurements were performed on eight mechanically ventilated patients with acute respiratory distress syndrome. A maneuver with step increase of airway pressure was performed. EIT raw data were reconstructed offline with (1) filtered back-projection (BP); (2) the Dräger algorithm based on linearized Newton–Raphson (DR); (3) the GREIT (Graz consensus reconstruction algorithm for EIT) reconstruction algorithm with a circular forward model (GR C ) and (4) GREIT with individual thorax geometry (GR T ). Individual thorax contours were automatically determined from the routine computed tomography images. Five indices were calculated on the resulting EIT images respectively: (a) the ratio between tidal and deep inflation impedance changes; (b) tidal impedance changes in the right and left lungs; (c) center of gravity; (d) the global inhomogeneity index and (e) ventilation delay at mid-dorsal regions. No significant differences were found in all examined indices among the four reconstruction algorithms (p > 0.2, Kruskal–Wallis test). The examined algorithms used for EIT image reconstruction do not influence the selected indices derived from the EIT image analysis. Indices that validated for images with one reconstruction algorithm are also valid for other reconstruction algorithms. (paper)

  13. The influence of image reconstruction algorithms on linear thorax EIT image analysis of ventilation.

    Science.gov (United States)

    Zhao, Zhanqi; Frerichs, Inéz; Pulletz, Sven; Müller-Lisse, Ullrich; Möller, Knut

    2014-06-01

    Analysis methods of electrical impedance tomography (EIT) images based on different reconstruction algorithms were examined. EIT measurements were performed on eight mechanically ventilated patients with acute respiratory distress syndrome. A maneuver with step increase of airway pressure was performed. EIT raw data were reconstructed offline with (1) filtered back-projection (BP); (2) the Dräger algorithm based on linearized Newton-Raphson (DR); (3) the GREIT (Graz consensus reconstruction algorithm for EIT) reconstruction algorithm with a circular forward model (GR(C)) and (4) GREIT with individual thorax geometry (GR(T)). Individual thorax contours were automatically determined from the routine computed tomography images. Five indices were calculated on the resulting EIT images respectively: (a) the ratio between tidal and deep inflation impedance changes; (b) tidal impedance changes in the right and left lungs; (c) center of gravity; (d) the global inhomogeneity index and (e) ventilation delay at mid-dorsal regions. No significant differences were found in all examined indices among the four reconstruction algorithms (p > 0.2, Kruskal-Wallis test). The examined algorithms used for EIT image reconstruction do not influence the selected indices derived from the EIT image analysis. Indices that validated for images with one reconstruction algorithm are also valid for other reconstruction algorithms.

  14. Image Reconstruction of Metal Pipe in Electrical Resistance Tomography

    Directory of Open Access Journals (Sweden)

    Suzanna RIDZUAN AW

    2017-02-01

    Full Text Available This paper demonstrates a Linear Back Projection (LBP algorithm based on the reconstruction of conductivity distributions to identify different sizes and locations of bubble phantoms in a metal pipe. Both forward and inverse problems are discussed. Reconstructed images of the phantoms under test conditions are presented. From the results, it was justified that the sensitivity maps of the conducting boundary strategy can be applied successfully in identifying the location for the phantom of interest using LBP algorithm. Additionally, the number and spatial distribution of the bubble phantoms can be clearly distinguished at any location in the pipeline. It was also shown that the reconstructed images agree well with the bubble phantoms.

  15. The feasibility of images reconstructed with the method of sieves

    International Nuclear Information System (INIS)

    Veklerov, E.; Llacer, J.

    1990-01-01

    The concept of sieves has been applied with the maximum likelihood estimator (MLE) to image reconstruction. While it makes it possible to recover smooth images consistent with the data, the degree of smoothness provided by it is arbitrary. It is shown that the concept of feasibility is able to resolve this arbitrariness. By varying the values of parameters determining the degree of smoothness, one can generate images on both sides of the feasibility region, as well as within the region. Feasible images recovered by using different sieve parameters are compared with feasible results of other procedures. One- and two-dimensional examples using both simulated and real data sets are considered

  16. Electron image reconstruction of helical protein assemblies

    International Nuclear Information System (INIS)

    Cremers, A.F.M.

    1980-01-01

    The analysis of projections of large ordered biological systems obtained by electron microscopy of negatively stained specimens is described. The biological structures amenable to this approach are constructed from a large number of identical protein molecules, which are arranged according to helical symmetry. Electron images of these structures generally contain sufficient information in order to calculate a three-dimensional density map. (Auth.)

  17. Single Image Super Resolution via Sparse Reconstruction

    NARCIS (Netherlands)

    Kruithof, M.C.; Eekeren, A.W.M. van; Dijk, J.; Schutte, K.

    2012-01-01

    High resolution sensors are required for recognition purposes. Low resolution sensors, however, are still widely used. Software can be used to increase the resolution of such sensors. One way of increasing the resolution of the images produced is using multi-frame super resolution algorithms.

  18. Realise : reconstruction of reality from image sequences

    NARCIS (Netherlands)

    Leymarie, F.; de la Fortelle, A.; Koenderink, Jan J.; Kappers, A. M L; Stavridi, M.; van Ginneken, B.; Muller, S.; Krake, S.; Faugeras, O.; Robert, L.; Gauclin, C.; Laveau, S.; Zeller, C.; Anon,

    1996-01-01

    REALISE has for principal goals to extract from sequences of images, acquired with a moving camera, information necessary for determining the 3D (CAD-like) structure of a real-life scene together with information about the radiometric signatures of surfaces bounding the extracted 3D objects (e.g.

  19. Fluorescence Image Segmentation by using Digitally Reconstructed Fluorescence Images

    OpenAIRE

    Blumer, Clemens; Vivien, Cyprien; Oertner, Thomas G; Vetter, Thomas

    2011-01-01

    In biological experiments fluorescence imaging is used to image living and stimulated neurons. But the analysis of fluorescence images is a difficult task. It is not possible to conclude the shape of an object from fluorescence images alone. Therefore, it is not feasible to get good manual segmented nor ground truth data from fluorescence images. Supervised learning approaches are not possible without training data. To overcome this issues we propose to synthesize fluorescence images and call...

  20. RECONSTRUCTION OF HUMAN LUNG MORPHOLOGY MODELS FROM MAGNETIC RESONANCE IMAGES

    Science.gov (United States)

    Reconstruction of Human Lung Morphology Models from Magnetic Resonance ImagesT. B. Martonen (Experimental Toxicology Division, U.S. EPA, Research Triangle Park, NC 27709) and K. K. Isaacs (School of Public Health, University of North Carolina, Chapel Hill, NC 27514)

  1. Use of a model for 3D image reconstruction

    International Nuclear Information System (INIS)

    Delageniere, S.; Grangeat, P.

    1991-01-01

    We propose a software for 3D image reconstruction in transmission tomography. This software is based on the use of a model and of the RADON algorithm developed at LETI. The introduction of a markovian model helps us to enhance contrast and straitened the natural transitions existing in the objects studied, whereas standard transform methods smoothe them

  2. The edge artifact in the point-spread function-based PET reconstruction at different sphere-to-background ratios of radioactivity.

    Science.gov (United States)

    Kidera, Daisuke; Kihara, Ken; Akamatsu, Go; Mikasa, Shohei; Taniguchi, Takafumi; Tsutsui, Yuji; Takeshita, Toshiki; Maebatake, Akira; Miwa, Kenta; Sasaki, Masayuki

    2016-02-01

    The aim of this study was to quantitatively evaluate the edge artifacts in PET images reconstructed using the point-spread function (PSF) algorithm at different sphere-to-background ratios of radioactivity (SBRs). We used a NEMA IEC body phantom consisting of six spheres with 37, 28, 22, 17, 13 and 10 mm in inner diameter. The background was filled with (18)F solution with a radioactivity concentration of 2.65 kBq/mL. We prepared three sets of phantoms with SBRs of 16, 8, 4 and 2. The PET data were acquired for 20 min using a Biograph mCT scanner. The images were reconstructed with the baseline ordered subsets expectation maximization (OSEM) algorithm, and with the OSEM + PSF correction model (PSF). For the image reconstruction, the number of iterations ranged from one to 10. The phantom PET image analyses were performed by a visual assessment of the PET images and profiles, a contrast recovery coefficient (CRC), which is the ratio of SBR in the images to the true SBR, and the percent change in the maximum count between the OSEM and PSF images (Δ % counts). In the PSF images, the spheres with a diameter of 17 mm or larger were surrounded by a dense edge in comparison with the OSEM images. In the spheres with a diameter of 22 mm or smaller, an overshoot appeared in the center of the spheres as a sharp peak in the PSF images in low SBR. These edge artifacts were clearly observed in relation to the increase of the SBR. The overestimation of the CRC was observed in 13 mm spheres in the PSF images. In the spheres with a diameter of 17 mm or smaller, the Δ % counts increased with an increasing SBR. The Δ % counts increased to 91 % in the 10-mm sphere at the SBR of 16. The edge artifacts in the PET images reconstructed using the PSF algorithm increased with an increasing SBR. In the small spheres, the edge artifact was observed as a sharp peak at the center of spheres and could result in overestimation.

  3. Image quality of multiplanar reconstruction of pulmonary CT scans using adaptive statistical iterative reconstruction.

    Science.gov (United States)

    Honda, O; Yanagawa, M; Inoue, A; Kikuyama, A; Yoshida, S; Sumikawa, H; Tobino, K; Koyama, M; Tomiyama, N

    2011-04-01

    We investigated the image quality of multiplanar reconstruction (MPR) using adaptive statistical iterative reconstruction (ASIR). Inflated and fixed lungs were scanned with a garnet detector CT in high-resolution mode (HR mode) or non-high-resolution (HR) mode, and MPR images were then reconstructed. Observers compared 15 MPR images of ASIR (40%) and ASIR (80%) with those of ASIR (0%), and assessed image quality using a visual five-point scale (1, definitely inferior; 5, definitely superior), with particular emphasis on normal pulmonary structures, artefacts, noise and overall image quality. The mean overall image quality scores in HR mode were 3.67 with ASIR (40%) and 4.97 with ASIR (80%). Those in non-HR mode were 3.27 with ASIR (40%) and 3.90 with ASIR (80%). The mean artefact scores in HR mode were 3.13 with ASIR (40%) and 3.63 with ASIR (80%), but those in non-HR mode were 2.87 with ASIR (40%) and 2.53 with ASIR (80%). The mean scores of the other parameters were greater than 3, whereas those in HR mode were higher than those in non-HR mode. There were significant differences between ASIR (40%) and ASIR (80%) in overall image quality (pASIR did not suppress the severe artefacts of contrast medium. In general, MPR image quality with ASIR (80%) was superior to that with ASIR (40%). However, there was an increased incidence of artefacts by ASIR when CT images were obtained in non-HR mode.

  4. Bayesian PET image reconstruction incorporating anato-functional joint entropy

    International Nuclear Information System (INIS)

    Tang Jing; Rahmim, Arman

    2009-01-01

    We developed a maximum a posterior (MAP) reconstruction method for positron emission tomography (PET) image reconstruction incorporating magnetic resonance (MR) image information, with the joint entropy between the PET and MR image features serving as the regularization constraint. A non-parametric method was used to estimate the joint probability density of the PET and MR images. Using realistically simulated PET and MR human brain phantoms, the quantitative performance of the proposed algorithm was investigated. Incorporation of the anatomic information via this technique, after parameter optimization, was seen to dramatically improve the noise versus bias tradeoff in every region of interest, compared to the result from using conventional MAP reconstruction. In particular, hot lesions in the FDG PET image, which had no anatomical correspondence in the MR image, also had improved contrast versus noise tradeoff. Corrections were made to figures 3, 4 and 6, and to the second paragraph of section 3.1 on 13 November 2009. The corrected electronic version is identical to the print version.

  5. An automated 3D reconstruction method of UAV images

    Science.gov (United States)

    Liu, Jun; Wang, He; Liu, Xiaoyang; Li, Feng; Sun, Guangtong; Song, Ping

    2015-10-01

    In this paper a novel fully automated 3D reconstruction approach based on low-altitude unmanned aerial vehicle system (UAVs) images will be presented, which does not require previous camera calibration or any other external prior knowledge. Dense 3D point clouds are generated by integrating orderly feature extraction, image matching, structure from motion (SfM) and multi-view stereo (MVS) algorithms, overcoming many of the cost, time limitations of rigorous photogrammetry techniques. An image topology analysis strategy is introduced to speed up large scene reconstruction by taking advantage of the flight-control data acquired by UAV. Image topology map can significantly reduce the running time of feature matching by limiting the combination of images. A high-resolution digital surface model of the study area is produced base on UAV point clouds by constructing the triangular irregular network. Experimental results show that the proposed approach is robust and feasible for automatic 3D reconstruction of low-altitude UAV images, and has great potential for the acquisition of spatial information at large scales mapping, especially suitable for rapid response and precise modelling in disaster emergency.

  6. Improvement of Quality of Reconstructed Images in Multi-Frame Fresnel Digital Holography

    International Nuclear Information System (INIS)

    Xiao-Wei, Lu; Jing-Zhen, Li; Hong-Yi, Chen

    2010-01-01

    A modified reconstruction algorithm to improve the quality of reconstructed images of multi-frame Fresnel digital holography is presented. When the reference beams are plane or spherical waves with azimuth encoding, by introducing two spherical wave factors, images can be reconstructed with only one time Fourier transform. In numerical simulation, this algorithm could simplify the reconstruction process and improve the signal-to-noise ratio of the reconstructed images. In single-frame reconstruction experiments, the accurate reconstructed image is obtained with this simplified algorithm

  7. Terahertz Imaging for Biomedical Applications Pattern Recognition and Tomographic Reconstruction

    CERN Document Server

    Yin, Xiaoxia; Abbott, Derek

    2012-01-01

    Terahertz Imaging for Biomedical Applications: Pattern Recognition and Tomographic Reconstruction presents the necessary algorithms needed to assist screening, diagnosis, and treatment, and these algorithms will play a critical role in the accurate detection of abnormalities present in biomedical imaging. Terahertz biomedical imaging has become an area of interest due to its ability to simultaneously acquire both image and spectral information. Terahertz imaging systems are being commercialized with an increasing number of trials performed in a biomedical setting. Terahertz tomographic imaging and detection technology contributes to the ability to identify opaque objects with clear boundaries,and would be useful to both in vivo and ex vivo environments. This book also: Introduces terahertz radiation techniques and provides a number of topical examples of signal and image processing, as well as machine learning Presents the most recent developments in an emerging field, terahertz radiation Utilizes new methods...

  8. Three-dimensional reconstruction of functional brain images

    International Nuclear Information System (INIS)

    Inoue, Masato; Shoji, Kazuhiko; Kojima, Hisayoshi; Hirano, Shigeru; Naito, Yasushi; Honjo, Iwao

    1999-01-01

    We consider PET (positron emission tomography) measurement with SPM (Statistical Parametric Mapping) analysis to be one of the most useful methods to identify activated areas of the brain involved in language processing. SPM is an effective analytical method that detects markedly activated areas over the whole brain. However, with the conventional presentations of these functional brain images, such as horizontal slices, three directional projection, or brain surface coloring, makes understanding and interpreting the positional relationships among various brain areas difficult. Therefore, we developed three-dimensionally reconstructed images from these functional brain images to improve the interpretation. The subjects were 12 normal volunteers. The following three types of images were constructed: routine images by SPM, three-dimensional static images, and three-dimensional dynamic images, after PET images were analyzed by SPM during daily dialog listening. The creation of images of both the three-dimensional static and dynamic types employed the volume rendering method by VTK (The Visualization Toolkit). Since the functional brain images did not include original brain images, we synthesized SPM and MRI brain images by self-made C++ programs. The three-dimensional dynamic images were made by sequencing static images with available software. Images of both the three-dimensional static and dynamic types were processed by a personal computer system. Our newly created images showed clearer positional relationships among activated brain areas compared to the conventional method. To date, functional brain images have been employed in fields such as neurology or neurosurgery, however, these images may be useful even in the field of otorhinolaryngology, to assess hearing and speech. Exact three-dimensional images based on functional brain images are important for exact and intuitive interpretation, and may lead to new developments in brain science. Currently, the surface

  9. Three-dimensional reconstruction of functional brain images

    Energy Technology Data Exchange (ETDEWEB)

    Inoue, Masato; Shoji, Kazuhiko; Kojima, Hisayoshi; Hirano, Shigeru; Naito, Yasushi; Honjo, Iwao [Kyoto Univ. (Japan)

    1999-08-01

    We consider PET (positron emission tomography) measurement with SPM (Statistical Parametric Mapping) analysis to be one of the most useful methods to identify activated areas of the brain involved in language processing. SPM is an effective analytical method that detects markedly activated areas over the whole brain. However, with the conventional presentations of these functional brain images, such as horizontal slices, three directional projection, or brain surface coloring, makes understanding and interpreting the positional relationships among various brain areas difficult. Therefore, we developed three-dimensionally reconstructed images from these functional brain images to improve the interpretation. The subjects were 12 normal volunteers. The following three types of images were constructed: routine images by SPM, three-dimensional static images, and three-dimensional dynamic images, after PET images were analyzed by SPM during daily dialog listening. The creation of images of both the three-dimensional static and dynamic types employed the volume rendering method by VTK (The Visualization Toolkit). Since the functional brain images did not include original brain images, we synthesized SPM and MRI brain images by self-made C++ programs. The three-dimensional dynamic images were made by sequencing static images with available software. Images of both the three-dimensional static and dynamic types were processed by a personal computer system. Our newly created images showed clearer positional relationships among activated brain areas compared to the conventional method. To date, functional brain images have been employed in fields such as neurology or neurosurgery, however, these images may be useful even in the field of otorhinolaryngology, to assess hearing and speech. Exact three-dimensional images based on functional brain images are important for exact and intuitive interpretation, and may lead to new developments in brain science. Currently, the surface

  10. Sparse Reconstruction Schemes for Nonlinear Electromagnetic Imaging

    KAUST Repository

    Desmal, Abdulla

    2016-03-01

    Electromagnetic imaging is the problem of determining material properties from scattered fields measured away from the domain under investigation. Solving this inverse problem is a challenging task because (i) it is ill-posed due to the presence of (smoothing) integral operators used in the representation of scattered fields in terms of material properties, and scattered fields are obtained at a finite set of points through noisy measurements; and (ii) it is nonlinear simply due the fact that scattered fields are nonlinear functions of the material properties. The work described in this thesis tackles the ill-posedness of the electromagnetic imaging problem using sparsity-based regularization techniques, which assume that the scatterer(s) occupy only a small fraction of the investigation domain. More specifically, four novel imaging methods are formulated and implemented. (i) Sparsity-regularized Born iterative method iteratively linearizes the nonlinear inverse scattering problem and each linear problem is regularized using an improved iterative shrinkage algorithm enforcing the sparsity constraint. (ii) Sparsity-regularized nonlinear inexact Newton method calls for the solution of a linear system involving the Frechet derivative matrix of the forward scattering operator at every iteration step. For faster convergence, the solution of this matrix system is regularized under the sparsity constraint and preconditioned by leveling the matrix singular values. (iii) Sparsity-regularized nonlinear Tikhonov method directly solves the nonlinear minimization problem using Landweber iterations, where a thresholding function is applied at every iteration step to enforce the sparsity constraint. (iv) This last scheme is accelerated using a projected steepest descent method when it is applied to three-dimensional investigation domains. Projection replaces the thresholding operation and enforces the sparsity constraint. Numerical experiments, which are carried out using

  11. A novel data processing technique for image reconstruction of penumbral imaging

    Science.gov (United States)

    Xie, Hongwei; Li, Hongyun; Xu, Zeping; Song, Guzhou; Zhang, Faqiang; Zhou, Lin

    2011-06-01

    CT image reconstruction technique was applied to the data processing of the penumbral imaging. Compared with other traditional processing techniques for penumbral coded pinhole image such as Wiener, Lucy-Richardson and blind technique, this approach is brand new. In this method, the coded aperture processing method was used for the first time independent to the point spread function of the image diagnostic system. In this way, the technical obstacles was overcome in the traditional coded pinhole image processing caused by the uncertainty of point spread function of the image diagnostic system. Then based on the theoretical study, the simulation of penumbral imaging and image reconstruction was carried out to provide fairly good results. While in the visible light experiment, the point source of light was used to irradiate a 5mm×5mm object after diffuse scattering and volume scattering. The penumbral imaging was made with aperture size of ~20mm. Finally, the CT image reconstruction technique was used for image reconstruction to provide a fairly good reconstruction result.

  12. Scattering calculation and image reconstruction using elevation-focused beams.

    Science.gov (United States)

    Duncan, David P; Astheimer, Jeffrey P; Waag, Robert C

    2009-05-01

    Pressure scattered by cylindrical and spherical objects with elevation-focused illumination and reception has been analytically calculated, and corresponding cross sections have been reconstructed with a two-dimensional algorithm. Elevation focusing was used to elucidate constraints on quantitative imaging of three-dimensional objects with two-dimensional algorithms. Focused illumination and reception are represented by angular spectra of plane waves that were efficiently computed using a Fourier interpolation method to maintain the same angles for all temporal frequencies. Reconstructions were formed using an eigenfunction method with multiple frequencies, phase compensation, and iteration. The results show that the scattered pressure reduces to a two-dimensional expression, and two-dimensional algorithms are applicable when the region of a three-dimensional object within an elevation-focused beam is approximately constant in elevation. The results also show that energy scattered out of the reception aperture by objects contained within the focused beam can result in the reconstructed values of attenuation slope being greater than true values at the boundary of the object. Reconstructed sound speed images, however, appear to be relatively unaffected by the loss in scattered energy. The broad conclusion that can be drawn from these results is that two-dimensional reconstructions require compensation to account for uncaptured three-dimensional scattering.

  13. Three-dimensional image reconstruction from stereo DSA

    International Nuclear Information System (INIS)

    Sakamoto, Kiyoshi; Kotoura, Noriko; Umehara, Takayoshi; Yamada, Eiji; Inaba, Tomohiro; Itou, Hiroshi

    1999-01-01

    The technique of interventional radiology has spread rapidly in recent years, and three-dimensional information from blood vessel images is being sought to enhance examinations. Stereo digital subtraction angiography (DSA) and rotational DSA were developed for that purpose. However, it is difficult with stereo DSA to observe the image pair during examination and to obtain positional information on blood vessels. Further, the exposure dose is increased in rotational DSA when many mask images need to be collected, and the patient is required to hold his or her breath for a long duration. We therefore devised a technique to construct three-dimensional blood vessel images by employing geometrical information extracted from stereo DSA images using the right and left images. We used a judgment method based on the correlation coefficient, although we had to extract an equal blood vessel from the right and left images to determine the three-dimensional coordinates of the blood vessel. The reconstructed three-dimensional blood vessels were projected from various angles, again by using a virtual focus, and new images were created. These image groups were displayed as rotational images by the animation display function incorporated in the DSA device. This system can observe blood vessel images of the same phase at a free angle, although the image quality is inferior to that of rotational DSA. In addition, because collection of the mask images is reduced, exposure dose can be decreased. Further, the system offers enhanced safety because no mechanical movement of the imaging system is involved. (author)

  14. Image quality of iterative reconstruction in cranial CT imaging: comparison of model-based iterative reconstruction (MBIR) and adaptive statistical iterative reconstruction (ASiR).

    Science.gov (United States)

    Notohamiprodjo, S; Deak, Z; Meurer, F; Maertz, F; Mueck, F G; Geyer, L L; Wirth, S

    2015-01-01

    The purpose of this study was to compare cranial CT (CCT) image quality (IQ) of the MBIR algorithm with standard iterative reconstruction (ASiR). In this institutional review board (IRB)-approved study, raw data sets of 100 unenhanced CCT examinations (120 kV, 50-260 mAs, 20 mm collimation, 0.984 pitch) were reconstructed with both ASiR and MBIR. Signal-to-noise (SNR) and contrast-to-noise (CNR) were calculated from attenuation values measured in caudate nucleus, frontal white matter, anterior ventricle horn, fourth ventricle, and pons. Two radiologists, who were blinded to the reconstruction algorithms, evaluated anonymized multiplanar reformations of 2.5 mm with respect to depiction of different parenchymal structures and impact of artefacts on IQ with a five-point scale (0: unacceptable, 1: less than average, 2: average, 3: above average, 4: excellent). MBIR decreased artefacts more effectively than ASiR (p ASiR was 2 (p ASiR (p ASiR. As CCT is an examination that is frequently required, the use of MBIR may allow for substantial reduction of radiation exposure caused by medical diagnostics. • Model-Based iterative reconstruction (MBIR) effectively decreased artefacts in cranial CT. • MBIR reconstructed images were rated with significantly higher scores for image quality. • Model-Based iterative reconstruction may allow reduced-dose diagnostic examination protocols.

  15. Evaluation of full time and half time acquired cardiac perfusion images and its correlation with coronary angiography

    International Nuclear Information System (INIS)

    Madhusudhanan, P.; Kapoor, A.; Arya, A.; Ora, M.; Kheruka, S.; Dube, V.; Uttam Kumar; Verma, R.S.; Singh, R.D.; Gambhir, S.

    2010-01-01

    Full text: The myocardial perfusion study takes a longer time to complete. A reduction in acquisition time would mean reduced patient motion related artifacts, improvement in camera efficiency and reduction in cost. Iterative reconstruction algorithms produce more accurate images with fewer artifacts. Materials and Methods: Seventy three patients undergoing myocardial perfusion imaging were selected for additional half time acquisition. Patients with suspected or known coronary artery disease who have undergone coronary angiography recently were preferably included. Images were analysed in 4 groups - full time FBP, half time FBP, half time OSEM and half time OSEM. Three independent observers blinded to the clinical data and the acquisition protocol analysed images for change in image quality between these groups. Semiquantitative parameters of summed stress score, summed rest score, summed difference score and left ventricular ejection fraction were also compared using appropriate statistical methods. Results: No difference was noted in SSS, SRS, SDS and LVEF calculated for full time and half time. However, significant difference was found between SSS, SRS and SDS calculated for FBP and OSEM processed half time studies and no significant difference for LVEF calculated for these two groups. Significant change in image quality was noted by 2 observers only in 1.4% and 2.7% of cases. A true positivity rate of 88% was seen in comparison with coronary angiography. Conclusion: Gated myocardial perfusion SPECT images acquired in half the routine scan time provides equal diagnostic information compared to a conventional full time study, regardless of the processing protocol

  16. Optimized 3D Street Scene Reconstruction from Driving Recorder Images

    Directory of Open Access Journals (Sweden)

    Yongjun Zhang

    2015-07-01

    Full Text Available The paper presents an automatic region detection based method to reconstruct street scenes from driving recorder images. The driving recorder in this paper is a dashboard camera that collects images while the motor vehicle is moving. An enormous number of moving vehicles are included in the collected data because the typical recorders are often mounted in the front of moving vehicles and face the forward direction, which can make matching points on vehicles and guardrails unreliable. Believing that utilizing these image data can reduce street scene reconstruction and updating costs because of their low price, wide use, and extensive shooting coverage, we therefore proposed a new method, which is called the Mask automatic detecting method, to improve the structure results from the motion reconstruction. Note that we define vehicle and guardrail regions as “mask” in this paper since the features on them should be masked out to avoid poor matches. After removing the feature points in our new method, the camera poses and sparse 3D points that are reconstructed with the remaining matches. Our contrast experiments with the typical pipeline of structure from motion (SfM reconstruction methods, such as Photosynth and VisualSFM, demonstrated that the Mask decreased the root-mean-square error (RMSE of the pairwise matching results, which led to more accurate recovering results from the camera-relative poses. Removing features from the Mask also increased the accuracy of point clouds by nearly 30%–40% and corrected the problems of the typical methods on repeatedly reconstructing several buildings when there was only one target building.

  17. Analyser-based phase contrast image reconstruction using geometrical optics

    International Nuclear Information System (INIS)

    Kitchen, M J; Pavlov, K M; Siu, K K W; Menk, R H; Tromba, G; Lewis, R A

    2007-01-01

    Analyser-based phase contrast imaging can provide radiographs of exceptional contrast at high resolution (<100 μm), whilst quantitative phase and attenuation information can be extracted using just two images when the approximations of geometrical optics are satisfied. Analytical phase retrieval can be performed by fitting the analyser rocking curve with a symmetric Pearson type VII function. The Pearson VII function provided at least a 10% better fit to experimentally measured rocking curves than linear or Gaussian functions. A test phantom, a hollow nylon cylinder, was imaged at 20 keV using a Si(1 1 1) analyser at the ELETTRA synchrotron radiation facility. Our phase retrieval method yielded a more accurate object reconstruction than methods based on a linear fit to the rocking curve. Where reconstructions failed to map expected values, calculations of the Takagi number permitted distinction between the violation of the geometrical optics conditions and the failure of curve fitting procedures. The need for synchronized object/detector translation stages was removed by using a large, divergent beam and imaging the object in segments. Our image acquisition and reconstruction procedure enables quantitative phase retrieval for systems with a divergent source and accounts for imperfections in the analyser

  18. Robust linearized image reconstruction for multifrequency EIT of the breast.

    Science.gov (United States)

    Boverman, Gregory; Kao, Tzu-Jen; Kulkarni, Rujuta; Kim, Bong Seok; Isaacson, David; Saulnier, Gary J; Newell, Jonathan C

    2008-10-01

    Electrical impedance tomography (EIT) is a developing imaging modality that is beginning to show promise for detecting and characterizing tumors in the breast. At Rensselaer Polytechnic Institute, we have developed a combined EIT-tomosynthesis system that allows for the coregistered and simultaneous analysis of the breast using EIT and X-ray imaging. A significant challenge in EIT is the design of computationally efficient image reconstruction algorithms which are robust to various forms of model mismatch. Specifically, we have implemented a scaling procedure that is robust to the presence of a thin highly-resistive layer of skin at the boundary of the breast and we have developed an algorithm to detect and exclude from the image reconstruction electrodes that are in poor contact with the breast. In our initial clinical studies, it has been difficult to ensure that all electrodes make adequate contact with the breast, and thus procedures for the use of data sets containing poorly contacting electrodes are particularly important. We also present a novel, efficient method to compute the Jacobian matrix for our linearized image reconstruction algorithm by reducing the computation of the sensitivity for each voxel to a quadratic form. Initial clinical results are presented, showing the potential of our algorithms to detect and localize breast tumors.

  19. Development of Image Reconstruction Algorithms in electrical Capacitance Tomography

    International Nuclear Information System (INIS)

    Fernandez Marron, J. L.; Alberdi Primicia, J.; Barcala Riveira, J. M.

    2007-01-01

    The Electrical Capacitance Tomography (ECT) has not obtained a good development in order to be used at industrial level. That is due first to difficulties in the measurement of very little capacitances (in the range of femto farads) and second to the problem of reconstruction on- line of the images. This problem is due also to the small numbers of electrodes (maximum 16), that made the usual algorithms of reconstruction has many errors. In this work it is described a new purely geometrical method that could be used for this purpose. (Author) 4 refs

  20. 3D Tomographic Image Reconstruction using CUDA C

    International Nuclear Information System (INIS)

    Dominguez, J. S.; Assis, J. T.; Oliveira, L. F. de

    2011-01-01

    This paper presents the study and implementation of a software for three dimensional reconstruction of images obtained with a tomographic system using the capabilities of Graphic Processing Units(GPU). The reconstruction by filtered back-projection method was developed using the CUDA C, for maximum utilization of the processing capabilities of GPUs to solve computational problems with large computational cost and highly parallelizable. It was discussed the potential of GPUs and shown its advantages to solving this kind of problems. The results in terms of runtime will be compared with non-parallelized implementations and must show a great reduction of processing time. (Author)

  1. Scattering Correction For Image Reconstruction In Flash Radiography

    International Nuclear Information System (INIS)

    Cao, Liangzhi; Wang, Mengqi; Wu, Hongchun; Liu, Zhouyu; Cheng, Yuxiong; Zhang, Hongbo

    2013-01-01

    Scattered photons cause blurring and distortions in flash radiography, reducing the accuracy of image reconstruction significantly. The effect of the scattered photons is taken into account and an iterative deduction of the scattered photons is proposed to amend the scattering effect for image restoration. In order to deduct the scattering contribution, the flux of scattered photons is estimated as the sum of two components. The single scattered component is calculated accurately together with the uncollided flux along the characteristic ray, while the multiple scattered component is evaluated using correction coefficients pre-obtained from Monte Carlo simulations.The arbitrary geometry pretreatment and ray tracing are carried out based on the customization of AutoCAD. With the above model, an Iterative Procedure for image restORation code, IPOR, is developed. Numerical results demonstrate that the IPOR code is much more accurate than the direct reconstruction solution without scattering correction and it has a very high computational efficiency

  2. Scattering Correction For Image Reconstruction In Flash Radiography

    Energy Technology Data Exchange (ETDEWEB)

    Cao, Liangzhi; Wang, Mengqi; Wu, Hongchun; Liu, Zhouyu; Cheng, Yuxiong; Zhang, Hongbo [Xi' an Jiaotong Univ., Xi' an (China)

    2013-08-15

    Scattered photons cause blurring and distortions in flash radiography, reducing the accuracy of image reconstruction significantly. The effect of the scattered photons is taken into account and an iterative deduction of the scattered photons is proposed to amend the scattering effect for image restoration. In order to deduct the scattering contribution, the flux of scattered photons is estimated as the sum of two components. The single scattered component is calculated accurately together with the uncollided flux along the characteristic ray, while the multiple scattered component is evaluated using correction coefficients pre-obtained from Monte Carlo simulations.The arbitrary geometry pretreatment and ray tracing are carried out based on the customization of AutoCAD. With the above model, an Iterative Procedure for image restORation code, IPOR, is developed. Numerical results demonstrate that the IPOR code is much more accurate than the direct reconstruction solution without scattering correction and it has a very high computational efficiency.

  3. Tomographic Image Reconstruction Using Training Images with Matrix and Tensor Formulations

    DEFF Research Database (Denmark)

    Soltani, Sara

    the image resolution compared to a classical reconstruction method such as Filtered Back Projection (FBP). Some priors for the tomographic reconstruction take the form of cross-section images of similar objects, providing a set of the so-called training images, that hold the key to the structural......Reducing X-ray exposure while maintaining the image quality is a major challenge in computed tomography (CT); since the imperfect data produced from the few view and/or low intensity projections results in low-quality images that are suffering from severe artifacts when using conventional...... information about the solution. The training images must be reliable and application-specific. This PhD project aims at providing a mathematical and computational framework for the use of training sets as non-parametric priors for the solution in tomographic image reconstruction. Through an unsupervised...

  4. Monte-Carlo simulations and image reconstruction for novel imaging scenarios in emission tomography

    International Nuclear Information System (INIS)

    Gillam, John E.; Rafecas, Magdalena

    2016-01-01

    Emission imaging incorporates both the development of dedicated devices for data acquisition as well as algorithms for recovering images from that data. Emission tomography is an indirect approach to imaging. The effect of device modification on the final image can be understood through both the way in which data are gathered, using simulation, and the way in which the image is formed from that data, or image reconstruction. When developing novel devices, systems and imaging tasks, accurate simulation and image reconstruction allow performance to be estimated, and in some cases optimized, using computational methods before or during the process of physical construction. However, there are a vast range of approaches, algorithms and pre-existing computational tools that can be exploited and the choices made will affect the accuracy of the in silico results and quality of the reconstructed images. On the one hand, should important physical effects be neglected in either the simulation or reconstruction steps, specific enhancements provided by novel devices may not be represented in the results. On the other hand, over-modeling of device characteristics in either step leads to large computational overheads that can confound timely results. Here, a range of simulation methodologies and toolkits are discussed, as well as reconstruction algorithms that may be employed in emission imaging. The relative advantages and disadvantages of a range of options are highlighted using specific examples from current research scenarios.

  5. Monte-Carlo simulations and image reconstruction for novel imaging scenarios in emission tomography

    Energy Technology Data Exchange (ETDEWEB)

    Gillam, John E. [The University of Sydney, Faculty of Health Sciences and The Brain and Mind Centre, Camperdown (Australia); Rafecas, Magdalena, E-mail: rafecas@imt.uni-luebeck.de [University of Lubeck, Institute of Medical Engineering, Ratzeburger Allee 160, 23538 Lübeck (Germany)

    2016-02-11

    Emission imaging incorporates both the development of dedicated devices for data acquisition as well as algorithms for recovering images from that data. Emission tomography is an indirect approach to imaging. The effect of device modification on the final image can be understood through both the way in which data are gathered, using simulation, and the way in which the image is formed from that data, or image reconstruction. When developing novel devices, systems and imaging tasks, accurate simulation and image reconstruction allow performance to be estimated, and in some cases optimized, using computational methods before or during the process of physical construction. However, there are a vast range of approaches, algorithms and pre-existing computational tools that can be exploited and the choices made will affect the accuracy of the in silico results and quality of the reconstructed images. On the one hand, should important physical effects be neglected in either the simulation or reconstruction steps, specific enhancements provided by novel devices may not be represented in the results. On the other hand, over-modeling of device characteristics in either step leads to large computational overheads that can confound timely results. Here, a range of simulation methodologies and toolkits are discussed, as well as reconstruction algorithms that may be employed in emission imaging. The relative advantages and disadvantages of a range of options are highlighted using specific examples from current research scenarios.

  6. Bias in iterative reconstruction of low-statistics PET data: benefits of a resolution model

    Energy Technology Data Exchange (ETDEWEB)

    Walker, M D; Asselin, M-C; Julyan, P J; Feldmann, M; Matthews, J C [School of Cancer and Enabling Sciences, Wolfson Molecular Imaging Centre, MAHSC, University of Manchester, Manchester M20 3LJ (United Kingdom); Talbot, P S [Mental Health and Neurodegeneration Research Group, Wolfson Molecular Imaging Centre, MAHSC, University of Manchester, Manchester M20 3LJ (United Kingdom); Jones, T, E-mail: matthew.walker@manchester.ac.uk [Academic Department of Radiation Oncology, Christie Hospital, University of Manchester, Manchester M20 4BX (United Kingdom)

    2011-02-21

    Iterative image reconstruction methods such as ordered-subset expectation maximization (OSEM) are widely used in PET. Reconstructions via OSEM are however reported to be biased for low-count data. We investigated this and considered the impact for dynamic PET. Patient listmode data were acquired in [{sup 11}C]DASB and [{sup 15}O]H{sub 2}O scans on the HRRT brain PET scanner. These data were subsampled to create many independent, low-count replicates. The data were reconstructed and the images from low-count data were compared to the high-count originals (from the same reconstruction method). This comparison enabled low-statistics bias to be calculated for the given reconstruction, as a function of the noise-equivalent counts (NEC). Two iterative reconstruction methods were tested, one with and one without an image-based resolution model (RM). Significant bias was observed when reconstructing data of low statistical quality, for both subsampled human and simulated data. For human data, this bias was substantially reduced by including a RM. For [{sup 11}C]DASB the low-statistics bias in the caudate head at 1.7 M NEC (approx. 30 s) was -5.5% and -13% with and without RM, respectively. We predicted biases in the binding potential of -4% and -10%. For quantification of cerebral blood flow for the whole-brain grey- or white-matter, using [{sup 15}O]H{sub 2}O and the PET autoradiographic method, a low-statistics bias of <2.5% and <4% was predicted for reconstruction with and without the RM. The use of a resolution model reduces low-statistics bias and can hence be beneficial for quantitative dynamic PET.

  7. SIRFING: Sparse Image Reconstruction For INterferometry using GPUs

    Science.gov (United States)

    Cranmer, Miles; Garsden, Hugh; Mitchell, Daniel A.; Greenhill, Lincoln

    2018-01-01

    We present a deconvolution code for radio interferometric imaging based on the compressed sensing algorithms in Garsden et al. (2015). Being computationally intensive, compressed sensing is ripe for parallelization over GPUs. Our compressed sensing implementation generates images using wavelets, and we have ported the underlying wavelet library to CUDA, targeting the spline filter reconstruction part of the algorithm. The speedup achieved is almost an order of magnitude. The code is modular but is also being integrated into the calibration and imaging pipeline in use by the LEDA project at the Long Wavelength Array (LWA) as well as by the Murchinson Widefield Array (MWA).

  8. D Reconstruction from Uav-Based Hyperspectral Images

    Science.gov (United States)

    Liu, L.; Xu, L.; Peng, J.

    2018-04-01

    Reconstructing the 3D profile from a set of UAV-based images can obtain hyperspectral information, as well as the 3D coordinate of any point on the profile. Our images are captured from the Cubert UHD185 (UHD) hyperspectral camera, which is a new type of high-speed onboard imaging spectrometer. And it can get both hyperspectral image and panchromatic image simultaneously. The panchromatic image have a higher spatial resolution than hyperspectral image, but each hyperspectral image provides considerable information on the spatial spectral distribution of the object. Thus there is an opportunity to derive a high quality 3D point cloud from panchromatic image and considerable spectral information from hyperspectral image. The purpose of this paper is to introduce our processing chain that derives a database which can provide hyperspectral information and 3D position of each point. First, We adopt a free and open-source software, Visual SFM which is based on structure from motion (SFM) algorithm, to recover 3D point cloud from panchromatic image. And then get spectral information of each point from hyperspectral image by a self-developed program written in MATLAB. The production can be used to support further research and applications.

  9. Comparison of power spectra for tomosynthesis projections and reconstructed images

    International Nuclear Information System (INIS)

    Engstrom, Emma; Reiser, Ingrid; Nishikawa, Robert

    2009-01-01

    Burgess et al. [Med. Phys. 28, 419-437 (2001)] showed that the power spectrum of mammographic breast background follows a power law and that lesion detectability is affected by the power-law exponent β which measures the amount of structure in the background. Following the study of Burgess et al., the authors measured and compared the power-law exponent of mammographic backgrounds in tomosynthesis projections and reconstructed slices to investigate the effect of tomosynthesis imaging on background structure. Our data set consisted of 55 patient cases. For each case, regions of interest (ROIs) were extracted from both projection images and reconstructed slices. The periodogram of each ROI was computed by taking the squared modulus of the Fourier transform of the ROI. The power-law exponent was determined for each periodogram and averaged across all ROIs extracted from all projections or reconstructed slices for each patient data set. For the projections, the mean β averaged across the 55 cases was 3.06 (standard deviation of 0.21), while it was 2.87 (0.24) for the corresponding reconstructions. The difference in β for a given patient between the projection ROIs and the reconstructed ROIs averaged across the 55 cases was 0.194, which was statistically significant (p<0.001). The 95% CI for the difference between the mean value of β for the projections and reconstructions was [0.170, 0.218]. The results are consistent with the observation that the amount of breast structure in the tomosynthesis slice is reduced compared to projection mammography and that this may lead to improved lesion detectability.

  10. Graph-cut based discrete-valued image reconstruction.

    Science.gov (United States)

    Tuysuzoglu, Ahmet; Karl, W Clem; Stojanovic, Ivana; Castañòn, David; Ünlü, M Selim

    2015-05-01

    Efficient graph-cut methods have been used with great success for labeling and denoising problems occurring in computer vision. Unfortunately, the presence of linear image mappings has prevented the use of these techniques in most discrete-amplitude image reconstruction problems. In this paper, we develop a graph-cut based framework for the direct solution of discrete amplitude linear image reconstruction problems cast as regularized energy function minimizations. We first analyze the structure of discrete linear inverse problem cost functions to show that the obstacle to the application of graph-cut methods to their solution is the variable mixing caused by the presence of the linear sensing operator. We then propose to use a surrogate energy functional that overcomes the challenges imposed by the sensing operator yet can be utilized efficiently in existing graph-cut frameworks. We use this surrogate energy functional to devise a monotonic iterative algorithm for the solution of discrete valued inverse problems. We first provide experiments using local convolutional operators and show the robustness of the proposed technique to noise and stability to changes in regularization parameter. Then we focus on nonlocal, tomographic examples where we consider limited-angle data problems. We compare our technique with state-of-the-art discrete and continuous image reconstruction techniques. Experiments show that the proposed method outperforms state-of-the-art techniques in challenging scenarios involving discrete valued unknowns.

  11. Missing data reconstruction using Gaussian mixture models for fingerprint images

    Science.gov (United States)

    Agaian, Sos S.; Yeole, Rushikesh D.; Rao, Shishir P.; Mulawka, Marzena; Troy, Mike; Reinecke, Gary

    2016-05-01

    Publisher's Note: This paper, originally published on 25 May 2016, was replaced with a revised version on 16 June 2016. If you downloaded the original PDF, but are unable to access the revision, please contact SPIE Digital Library Customer Service for assistance. One of the most important areas in biometrics is matching partial fingerprints in fingerprint databases. Recently, significant progress has been made in designing fingerprint identification systems for missing fingerprint information. However, a dependable reconstruction of fingerprint images still remains challenging due to the complexity and the ill-posed nature of the problem. In this article, both binary and gray-level images are reconstructed. This paper also presents a new similarity score to evaluate the performance of the reconstructed binary image. The offered fingerprint image identification system can be automated and extended to numerous other security applications such as postmortem fingerprints, forensic science, investigations, artificial intelligence, robotics, all-access control, and financial security, as well as for the verification of firearm purchasers, driver license applicants, etc.

  12. GPU based Monte Carlo for PET image reconstruction: parameter optimization

    International Nuclear Information System (INIS)

    Cserkaszky, Á; Légrády, D.; Wirth, A.; Bükki, T.; Patay, G.

    2011-01-01

    This paper presents the optimization of a fully Monte Carlo (MC) based iterative image reconstruction of Positron Emission Tomography (PET) measurements. With our MC re- construction method all the physical effects in a PET system are taken into account thus superior image quality is achieved in exchange for increased computational effort. The method is feasible because we utilize the enormous processing power of Graphical Processing Units (GPUs) to solve the inherently parallel problem of photon transport. The MC approach regards the simulated positron decays as samples in mathematical sums required in the iterative reconstruction algorithm, so to complement the fast architecture, our work of optimization focuses on the number of simulated positron decays required to obtain sufficient image quality. We have achieved significant results in determining the optimal number of samples for arbitrary measurement data, this allows to achieve the best image quality with the least possible computational effort. Based on this research recommendations can be given for effective partitioning of computational effort into the iterations in limited time reconstructions. (author)

  13. Hierarchical Bayesian sparse image reconstruction with application to MRFM.

    Science.gov (United States)

    Dobigeon, Nicolas; Hero, Alfred O; Tourneret, Jean-Yves

    2009-09-01

    This paper presents a hierarchical Bayesian model to reconstruct sparse images when the observations are obtained from linear transformations and corrupted by an additive white Gaussian noise. Our hierarchical Bayes model is well suited to such naturally sparse image applications as it seamlessly accounts for properties such as sparsity and positivity of the image via appropriate Bayes priors. We propose a prior that is based on a weighted mixture of a positive exponential distribution and a mass at zero. The prior has hyperparameters that are tuned automatically by marginalization over the hierarchical Bayesian model. To overcome the complexity of the posterior distribution, a Gibbs sampling strategy is proposed. The Gibbs samples can be used to estimate the image to be recovered, e.g., by maximizing the estimated posterior distribution. In our fully Bayesian approach, the posteriors of all the parameters are available. Thus, our algorithm provides more information than other previously proposed sparse reconstruction methods that only give a point estimate. The performance of the proposed hierarchical Bayesian sparse reconstruction method is illustrated on synthetic data and real data collected from a tobacco virus sample using a prototype MRFM instrument.

  14. Tomographic image reconstruction and rendering with texture-mapping hardware

    International Nuclear Information System (INIS)

    Azevedo, S.G.; Cabral, B.K.; Foran, J.

    1994-07-01

    The image reconstruction problem, also known as the inverse Radon transform, for x-ray computed tomography (CT) is found in numerous applications in medicine and industry. The most common algorithm used in these cases is filtered backprojection (FBP), which, while a simple procedure, is time-consuming for large images on any type of computational engine. Specially-designed, dedicated parallel processors are commonly used in medical CT scanners, whose results are then passed to graphics workstation for rendering and analysis. However, a fast direct FBP algorithm can be implemented on modern texture-mapping hardware in current high-end workstation platforms. This is done by casting the FBP algorithm as an image warping operation with summing. Texture-mapping hardware, such as that on the Silicon Graphics Reality Engine (TM), shows around 600 times speedup of backprojection over a CPU-based implementation (a 100 Mhz R4400 in this case). This technique has the further advantages of flexibility and rapid programming. In addition, the same hardware can be used for both image reconstruction and for volumetric rendering. The techniques can also be used to accelerate iterative reconstruction algorithms. The hardware architecture also allows more complex operations than straight-ray backprojection if they are required, including fan-beam, cone-beam, and curved ray paths, with little or no speed penalties

  15. Image reconstruction from limited angle Compton camera data

    International Nuclear Information System (INIS)

    Tomitani, T.; Hirasawa, M.

    2002-01-01

    The Compton camera is used for imaging the distributions of γ ray direction in a γ ray telescope for astrophysics and for imaging radioisotope distributions in nuclear medicine without the need for collimators. The integration of γ rays on a cone is measured with the camera, so that some sort of inversion method is needed. Parra found an analytical inversion algorithm based on spherical harmonics expansion of projection data. His algorithm is applicable to the full set of projection data. In this paper, six possible reconstruction algorithms that allow image reconstruction from projections with a finite range of scattering angles are investigated. Four algorithms have instability problems and two others are practical. However, the variance of the reconstructed image diverges in these two cases, so that window functions are introduced with which the variance becomes finite at a cost of spatial resolution. These two algorithms are compared in terms of variance. The algorithm based on the inversion of the summed back-projection is superior to the algorithm based on the inversion of the summed projection. (author)

  16. Complications of anterior cruciate ligament reconstruction: MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Papakonstantinou, Olympia; Chung, Christine B.; Chanchairujira, Kullanuch; Resnick, Donald L. [Department of Radiology, Veterans Affairs Medical Center, University of California, 3350 La Jolla Village Dr., San Diego, CA 92161 (United States)

    2003-05-01

    Arthroscopic reconstruction of the anterior cruciate ligament (ACL) using autografts or allografts is being performed with increasing frequency, particularly in young athletes. Although the procedure is generally well tolerated, with good success rates, early and late complications have been documented. As clinical manifestations of graft complications are often non-specific and plain radiographs cannot directly visualize the graft and the adjacent soft tissues, MR imaging has a definite role in the diagnosis of complications after ACL reconstruction and may direct subsequent therapeutic management. Our purpose is to review the normal MR imaging of the ACL graft and present the MR imaging findings of a wide spectrum of complications after ACL reconstruction, such as graft impingement, graft rupture, cystic degeneration of the graft, postoperative infection of the knee, diffuse and localized (i.e., cyclops lesion) arthrofibrosis, and associated donor site abnormalities. Awareness of the MR imaging findings of complications as well as the normal appearances of the normal ACL graft is essential for correct interpretation. (orig.)

  17. Complications of anterior cruciate ligament reconstruction: MR imaging

    International Nuclear Information System (INIS)

    Papakonstantinou, Olympia; Chung, Christine B.; Chanchairujira, Kullanuch; Resnick, Donald L.

    2003-01-01

    Arthroscopic reconstruction of the anterior cruciate ligament (ACL) using autografts or allografts is being performed with increasing frequency, particularly in young athletes. Although the procedure is generally well tolerated, with good success rates, early and late complications have been documented. As clinical manifestations of graft complications are often non-specific and plain radiographs cannot directly visualize the graft and the adjacent soft tissues, MR imaging has a definite role in the diagnosis of complications after ACL reconstruction and may direct subsequent therapeutic management. Our purpose is to review the normal MR imaging of the ACL graft and present the MR imaging findings of a wide spectrum of complications after ACL reconstruction, such as graft impingement, graft rupture, cystic degeneration of the graft, postoperative infection of the knee, diffuse and localized (i.e., cyclops lesion) arthrofibrosis, and associated donor site abnormalities. Awareness of the MR imaging findings of complications as well as the normal appearances of the normal ACL graft is essential for correct interpretation. (orig.)

  18. Analyser-based phase contrast image reconstruction using geometrical optics.

    Science.gov (United States)

    Kitchen, M J; Pavlov, K M; Siu, K K W; Menk, R H; Tromba, G; Lewis, R A

    2007-07-21

    Analyser-based phase contrast imaging can provide radiographs of exceptional contrast at high resolution (geometrical optics are satisfied. Analytical phase retrieval can be performed by fitting the analyser rocking curve with a symmetric Pearson type VII function. The Pearson VII function provided at least a 10% better fit to experimentally measured rocking curves than linear or Gaussian functions. A test phantom, a hollow nylon cylinder, was imaged at 20 keV using a Si(1 1 1) analyser at the ELETTRA synchrotron radiation facility. Our phase retrieval method yielded a more accurate object reconstruction than methods based on a linear fit to the rocking curve. Where reconstructions failed to map expected values, calculations of the Takagi number permitted distinction between the violation of the geometrical optics conditions and the failure of curve fitting procedures. The need for synchronized object/detector translation stages was removed by using a large, divergent beam and imaging the object in segments. Our image acquisition and reconstruction procedure enables quantitative phase retrieval for systems with a divergent source and accounts for imperfections in the analyser.

  19. Holographic images reconstructed from GMR-based fringe pattern

    Directory of Open Access Journals (Sweden)

    Kikuchi Hiroshi

    2013-01-01

    Full Text Available We have developed a magneto-optical spatial light modulator (MOSLM using giant magneto-resistance (GMR structures for realizing a holographic three-dimensional (3D display. For practical applications, reconstructed image of hologram consisting of GMR structures should be investigated in order to study the feasibility of the MOSLM. In this study, we fabricated a hologram with GMR based fringe-pattern and demonstrated a reconstructed image. A fringe-pattern convolving a crossshaped image was calculated by a conventional binary computer generated hologram (CGH technique. The CGH-pattern has 2,048 × 2,048 with 5 μm pixel pitch. The GMR stack consists of a Tb-Fe-Co/CoFe pinned layer, a Ag spacer, a Gd-Fe free layer for light modulation, and a Ru capping layer, was deposited by dc-magnetron sputtering. The GMR hologram was formed using photo-lithography and Krion milling processes, followed by the deposition of a Tb-Fe-Co reference layer with large coercivity and the same Kerr-rotation angle compared to the free layer, and a lift-off process. The reconstructed image of the ON-state was clearly observed and successfully distinguished from the OFF-state by switching the magnetization direction of the free-layer with an external magnetic field. These results indicate the possibility of realizing a holographic 3D display by the MOSLM using the GMR structures.

  20. Penalised Maximum Likelihood Simultaneous Longitudinal PET Image Reconstruction with Difference-Image Priors.

    Science.gov (United States)

    Ellis, Sam; Reader, Andrew J

    2018-04-26

    Many clinical contexts require the acquisition of multiple positron emission tomography (PET) scans of a single subject, for example to observe and quantify changes in functional behaviour in tumours after treatment in oncology. Typically, the datasets from each of these scans are reconstructed individually, without exploiting the similarities between them. We have recently shown that sharing information between longitudinal PET datasets by penalising voxel-wise differences during image reconstruction can improve reconstructed images by reducing background noise and increasing the contrast-to-noise ratio of high activity lesions. Here we present two additional novel longitudinal difference-image priors and evaluate their performance using 2D simulation studies and a 3D real dataset case study. We have previously proposed a simultaneous difference-image-based penalised maximum likelihood (PML) longitudinal image reconstruction method that encourages sparse difference images (DS-PML), and in this work we propose two further novel prior terms. The priors are designed to encourage longitudinal images with corresponding differences which have i) low entropy (DE-PML), and ii) high sparsity in their spatial gradients (DTV-PML). These two new priors and the originally proposed longitudinal prior were applied to 2D simulated treatment response [ 18 F]fluorodeoxyglucose (FDG) brain tumour datasets and compared to standard maximum likelihood expectation-maximisation (MLEM) reconstructions. These 2D simulation studies explored the effects of penalty strengths, tumour behaviour, and inter-scan coupling on reconstructed images. Finally, a real two-scan longitudinal data series acquired from a head and neck cancer patient was reconstructed with the proposed methods and the results compared to standard reconstruction methods. Using any of the three priors with an appropriate penalty strength produced images with noise levels equivalent to those seen when using standard

  1. An efficient simultaneous reconstruction technique for tomographic particle image velocimetry

    Science.gov (United States)

    Atkinson, Callum; Soria, Julio

    2009-10-01

    To date, Tomo-PIV has involved the use of the multiplicative algebraic reconstruction technique (MART), where the intensity of each 3D voxel is iteratively corrected to satisfy one recorded projection, or pixel intensity, at a time. This results in reconstruction times of multiple hours for each velocity field and requires considerable computer memory in order to store the associated weighting coefficients and intensity values for each point in the volume. In this paper, a rapid and less memory intensive reconstruction algorithm is presented based on a multiplicative line-of-sight (MLOS) estimation that determines possible particle locations in the volume, followed by simultaneous iterative correction. Reconstructions of simulated images are presented for two simultaneous algorithms (SART and SMART) as well as the now standard MART algorithm, which indicate that the same accuracy as MART can be achieved 5.5 times faster or 77 times faster with 15 times less memory if the processing and storage of the weighting matrix is considered. Application of MLOS-SMART and MART to a turbulent boundary layer at Re θ = 2200 using a 4 camera Tomo-PIV system with a volume of 1,000 × 1,000 × 160 voxels is discussed. Results indicate improvements in reconstruction speed of 15 times that of MART with precalculated weighting matrix, or 65 times if calculation of the weighting matrix is considered. Furthermore the memory needed to store a large weighting matrix and volume intensity is reduced by almost 40 times in this case.

  2. Reconstruction of hyperspectral image using matting model for classification

    Science.gov (United States)

    Xie, Weiying; Li, Yunsong; Ge, Chiru

    2016-05-01

    Although hyperspectral images (HSIs) captured by satellites provide much information in spectral regions, some bands are redundant or have large amounts of noise, which are not suitable for image analysis. To address this problem, we introduce a method for reconstructing the HSI with noise reduction and contrast enhancement using a matting model for the first time. The matting model refers to each spectral band of an HSI that can be decomposed into three components, i.e., alpha channel, spectral foreground, and spectral background. First, one spectral band of an HSI with more refined information than most other bands is selected, and is referred to as an alpha channel of the HSI to estimate the hyperspectral foreground and hyperspectral background. Finally, a combination operation is applied to reconstruct the HSI. In addition, the support vector machine (SVM) classifier and three sparsity-based classifiers, i.e., orthogonal matching pursuit (OMP), simultaneous OMP, and OMP based on first-order neighborhood system weighted classifiers, are utilized on the reconstructed HSI and the original HSI to verify the effectiveness of the proposed method. Specifically, using the reconstructed HSI, the average accuracy of the SVM classifier can be improved by as much as 19%.

  3. Parallel MR image reconstruction using augmented Lagrangian methods.

    Science.gov (United States)

    Ramani, Sathish; Fessler, Jeffrey A

    2011-03-01

    Magnetic resonance image (MRI) reconstruction using SENSitivity Encoding (SENSE) requires regularization to suppress noise and aliasing effects. Edge-preserving and sparsity-based regularization criteria can improve image quality, but they demand computation-intensive nonlinear optimization. In this paper, we present novel methods for regularized MRI reconstruction from undersampled sensitivity encoded data--SENSE-reconstruction--using the augmented Lagrangian (AL) framework for solving large-scale constrained optimization problems. We first formulate regularized SENSE-reconstruction as an unconstrained optimization task and then convert it to a set of (equivalent) constrained problems using variable splitting. We then attack these constrained versions in an AL framework using an alternating minimization method, leading to algorithms that can be implemented easily. The proposed methods are applicable to a general class of regularizers that includes popular edge-preserving (e.g., total-variation) and sparsity-promoting (e.g., l(1)-norm of wavelet coefficients) criteria and combinations thereof. Numerical experiments with synthetic and in vivo human data illustrate that the proposed AL algorithms converge faster than both general-purpose optimization algorithms such as nonlinear conjugate gradient (NCG) and state-of-the-art MFISTA.

  4. Digital filtering and reconstruction of coded aperture images

    International Nuclear Information System (INIS)

    Tobin, K.W. Jr.

    1987-01-01

    The real-time neutron radiography facility at the University of Virginia has been used for both transmission radiography and computed tomography. Recently, a coded aperture system has been developed to permit the extraction of three dimensional information from a low intensity field of radiation scattered by an extended object. Short wave-length radiations (e.g. neutrons) are not easily image because of the difficulties in achieving diffraction and refraction with a conventional lens imaging system. By using a coded aperture approach, an imaging system has been developed that records and reconstructs an object from an intensity distribution. This system has a signal-to-noise ratio that is proportional to the total open area of the aperture making it ideal for imaging with a limiting intensity radiation field. The main goal of this research was to develope and implement the digital methods and theory necessary for the reconstruction process. Several real-time video systems, attached to an Intellect-100 image processor, a DEC PDP-11 micro-computer, and a Convex-1 parallel processing mainframe were employed. This system, coupled with theoretical extensions and improvements, allowed for retrieval of information previously unobtainable by earlier optical methods. The effect of thermal noise, shot noise, and aperture related artifacts were examined so that new digital filtering techniques could be constructed and implemented. Results of image data filtering prior to and following the reconstruction process are reported. Improvements related to the different signal processing methods are emphasized. The application and advantages of this imaging technique to the field of non-destructive testing are also discussed

  5. PHOTOGRAMMETRIC 3D BUILDING RECONSTRUCTION FROM THERMAL IMAGES

    Directory of Open Access Journals (Sweden)

    E. Maset

    2017-08-01

    Full Text Available This paper addresses the problem of 3D building reconstruction from thermal infrared (TIR images. We show that a commercial Computer Vision software can be used to automatically orient sequences of TIR images taken from an Unmanned Aerial Vehicle (UAV and to generate 3D point clouds, without requiring any GNSS/INS data about position and attitude of the images nor camera calibration parameters. Moreover, we propose a procedure based on Iterative Closest Point (ICP algorithm to create a model that combines high resolution and geometric accuracy of RGB images with the thermal information deriving from TIR images. The process can be carried out entirely by the aforesaid software in a simple and efficient way.

  6. 3D Point Cloud Reconstruction from Single Plenoptic Image

    Directory of Open Access Journals (Sweden)

    F. Murgia

    2016-06-01

    Full Text Available Novel plenoptic cameras sample the light field crossing the main camera lens. The information available in a plenoptic image must be processed, in order to create the depth map of the scene from a single camera shot. In this paper a novel algorithm, for the reconstruction of 3D point cloud of the scene from a single plenoptic image, taken with a consumer plenoptic camera, is proposed. Experimental analysis is conducted on several test images, and results are compared with state of the art methodologies. The results are very promising, as the quality of the 3D point cloud from plenoptic image, is comparable with the quality obtained with current non-plenoptic methodologies, that necessitate more than one image.

  7. Stokes image reconstruction for two-color microgrid polarization imaging systems.

    Science.gov (United States)

    Lemaster, Daniel A

    2011-07-18

    The Air Force Research Laboratory has developed a new microgrid polarization imaging system capable of simultaneously reconstructing linear Stokes parameter images in two colors on a single focal plane array. In this paper, an effective method for extracting Stokes images is presented for this type of camera system. It is also shown that correlations between the color bands can be exploited to significantly increase overall spatial resolution. Test data is used to show the advantages of this approach over bilinear interpolation. The bounds (in terms of available reconstruction bandwidth) on image resolution are also provided.

  8. Model-based microwave image reconstruction: simulations and experiments

    International Nuclear Information System (INIS)

    Ciocan, Razvan; Jiang Huabei

    2004-01-01

    We describe an integrated microwave imaging system that can provide spatial maps of dielectric properties of heterogeneous media with tomographically collected data. The hardware system (800-1200 MHz) was built based on a lock-in amplifier with 16 fixed antennas. The reconstruction algorithm was implemented using a Newton iterative method with combined Marquardt-Tikhonov regularizations. System performance was evaluated using heterogeneous media mimicking human breast tissue. Finite element method coupled with the Bayliss and Turkel radiation boundary conditions were applied to compute the electric field distribution in the heterogeneous media of interest. The results show that inclusions embedded in a 76-diameter background medium can be quantitatively reconstructed from both simulated and experimental data. Quantitative analysis of the microwave images obtained suggests that an inclusion of 14 mm in diameter is the smallest object that can be fully characterized presently using experimental data, while objects as small as 10 mm in diameter can be quantitatively resolved with simulated data

  9. A maximum entropy reconstruction technique for tomographic particle image velocimetry

    International Nuclear Information System (INIS)

    Bilsky, A V; Lozhkin, V A; Markovich, D M; Tokarev, M P

    2013-01-01

    This paper studies a novel approach for reducing tomographic PIV computational complexity. The proposed approach is an algebraic reconstruction technique, termed MENT (maximum entropy). This technique computes the three-dimensional light intensity distribution several times faster than SMART, using at least ten times less memory. Additionally, the reconstruction quality remains nearly the same as with SMART. This paper presents the theoretical computation performance comparison for MENT, SMART and MART, followed by validation using synthetic particle images. Both the theoretical assessment and validation of synthetic images demonstrate significant computational time reduction. The data processing accuracy of MENT was compared to that of SMART in a slot jet experiment. A comparison of the average velocity profiles shows a high level of agreement between the results obtained with MENT and those obtained with SMART. (paper)

  10. Dual-source CT coronary imaging in heart transplant recipients: image quality and optimal reconstruction interval

    International Nuclear Information System (INIS)

    Bastarrika, Gorka; Arraiza, Maria; Pueyo, Jesus C.; Cecco, Carlo N. de; Ubilla, Matias; Mastrobuoni, Stefano; Rabago, Gregorio

    2008-01-01

    The image quality and optimal reconstruction interval for coronary arteries in heart transplant recipients undergoing non-invasive dual-source computed tomography (DSCT) coronary angiography was evaluated. Twenty consecutive heart transplant recipients who underwent DSCT coronary angiography were included (19 male, one female; mean age 63.1±10.7 years). Data sets were reconstructed in 5% steps from 30% to 80% of the R-R interval. Two blinded independent observers assessed the image quality of each coronary segments using a five-point scale (from 0 = not evaluative to 4=excellent quality). A total of 289 coronary segments in 20 heart transplant recipients were evaluated. Mean heart rate during the scan was 89.1±10.4 bpm. At the best reconstruction interval, diagnostic image quality (score ≥2) was obtained in 93.4% of the coronary segments (270/289) with a mean image quality score of 3.04± 0.63. Systolic reconstruction intervals provided better image quality scores than diastolic reconstruction intervals (overall mean quality scores obtained with the systolic and diastolic reconstructions 3.03±1.06 and 2.73±1.11, respectively; P<0.001). Different systolic reconstruction intervals (35%, 40%, 45% of RR interval) did not yield to significant differences in image quality scores for the coronary segments (P=0.74). Reconstructions obtained at the systolic phase of the cardiac cycle allowed excellent diagnostic image quality coronary angiograms in heart transplant recipients undergoing DSCT coronary angiography. (orig.)

  11. GPU based Monte Carlo for PET image reconstruction: detector modeling

    International Nuclear Information System (INIS)

    Légrády; Cserkaszky, Á; Lantos, J.; Patay, G.; Bükki, T.

    2011-01-01

    Monte Carlo (MC) calculations and Graphical Processing Units (GPUs) are almost like the dedicated hardware designed for the specific task given the similarities between visible light transport and neutral particle trajectories. A GPU based MC gamma transport code has been developed for Positron Emission Tomography iterative image reconstruction calculating the projection from unknowns to data at each iteration step taking into account the full physics of the system. This paper describes the simplified scintillation detector modeling and its effect on convergence. (author)

  12. Image reconstruction using Monte Carlo simulation and artificial neural networks

    International Nuclear Information System (INIS)

    Emert, F.; Missimner, J.; Blass, W.; Rodriguez, A.

    1997-01-01

    PET data sets are subject to two types of distortions during acquisition: the imperfect response of the scanner and attenuation and scattering in the active distribution. In addition, the reconstruction of voxel images from the line projections composing a data set can introduce artifacts. Monte Carlo simulation provides a means for modeling the distortions and artificial neural networks a method for correcting for them as well as minimizing artifacts. (author) figs., tab., refs

  13. Total variation superiorized conjugate gradient method for image reconstruction

    Science.gov (United States)

    Zibetti, Marcelo V. W.; Lin, Chuan; Herman, Gabor T.

    2018-03-01

    The conjugate gradient (CG) method is commonly used for the relatively-rapid solution of least squares problems. In image reconstruction, the problem can be ill-posed and also contaminated by noise; due to this, approaches such as regularization should be utilized. Total variation (TV) is a useful regularization penalty, frequently utilized in image reconstruction for generating images with sharp edges. When a non-quadratic norm is selected for regularization, as is the case for TV, then it is no longer possible to use CG. Non-linear CG is an alternative, but it does not share the efficiency that CG shows with least squares and methods such as fast iterative shrinkage-thresholding algorithms (FISTA) are preferred for problems with TV norm. A different approach to including prior information is superiorization. In this paper it is shown that the conjugate gradient method can be superiorized. Five different CG variants are proposed, including preconditioned CG. The CG methods superiorized by the total variation norm are presented and their performance in image reconstruction is demonstrated. It is illustrated that some of the proposed variants of the superiorized CG method can produce reconstructions of superior quality to those produced by FISTA and in less computational time, due to the speed of the original CG for least squares problems. In the Appendix we examine the behavior of one of the superiorized CG methods (we call it S-CG); one of its input parameters is a positive number ɛ. It is proved that, for any given ɛ that is greater than the half-squared-residual for the least squares solution, S-CG terminates in a finite number of steps with an output for which the half-squared-residual is less than or equal to ɛ. Importantly, it is also the case that the output will have a lower value of TV than what would be provided by unsuperiorized CG for the same value ɛ of the half-squared residual.

  14. Fan beam image reconstruction with generalized Fourier slice theorem.

    Science.gov (United States)

    Zhao, Shuangren; Yang, Kang; Yang, Kevin

    2014-01-01

    For parallel beam geometry the Fourier reconstruction works via the Fourier slice theorem (or central slice theorem, projection slice theorem). For fan beam situation, Fourier slice can be extended to a generalized Fourier slice theorem (GFST) for fan-beam image reconstruction. We have briefly introduced this method in a conference. This paper reintroduces the GFST method for fan beam geometry in details. The GFST method can be described as following: the Fourier plane is filled by adding up the contributions from all fanbeam projections individually; thereby the values in the Fourier plane are directly calculated for Cartesian coordinates such avoiding the interpolation from polar to Cartesian coordinates in the Fourier domain; inverse fast Fourier transform is applied to the image in Fourier plane and leads to a reconstructed image in spacial domain. The reconstructed image is compared between the result of the GFST method and the result from the filtered backprojection (FBP) method. The major differences of the GFST and the FBP methods are: (1) The interpolation process are at different data sets. The interpolation of the GFST method is at projection data. The interpolation of the FBP method is at filtered projection data. (2) The filtering process are done in different places. The filtering process of the GFST is at Fourier domain. The filtering process of the FBP method is the ramp filter which is done at projections. The resolution of ramp filter is variable with different location but the filter in the Fourier domain lead to resolution invariable with location. One advantage of the GFST method over the FBP method is in short scan situation, an exact solution can be obtained with the GFST method, but it can not be obtained with the FBP method. The calculation of both the GFST and the FBP methods are at O(N^3), where N is the number of pixel in one dimension.

  15. The gridding method for image reconstruction by Fourier transformation

    International Nuclear Information System (INIS)

    Schomberg, H.; Timmer, J.

    1995-01-01

    This paper explores a computational method for reconstructing an n-dimensional signal f from a sampled version of its Fourier transform f. The method involves a window function w and proceeds in three steps. First, the convolution g = w * f is computed numerically on a Cartesian grid, using the available samples of f. Then, g = wf is computed via the inverse discrete Fourier transform, and finally f is obtained as g/w. Due to the smoothing effect of the convolution, evaluating w * f is much less error prone than merely interpolating f. The method was originally devised for image reconstruction in radio astronomy, but is actually applicable to a broad range of reconstructive imaging methods, including magnetic resonance imaging and computed tomography. In particular, it provides a fast and accurate alternative to the filtered backprojection. The basic method has several variants with other applications, such as the equidistant resampling of arbitrarily sampled signals or the fast computation of the Radon (Hough) transform

  16. Enhanced imaging of microcalcifications in digital breast tomosynthesis through improved image-reconstruction algorithms

    International Nuclear Information System (INIS)

    Sidky, Emil Y.; Pan Xiaochuan; Reiser, Ingrid S.; Nishikawa, Robert M.; Moore, Richard H.; Kopans, Daniel B.

    2009-01-01

    Purpose: The authors develop a practical, iterative algorithm for image-reconstruction in undersampled tomographic systems, such as digital breast tomosynthesis (DBT). Methods: The algorithm controls image regularity by minimizing the image total p variation (TpV), a function that reduces to the total variation when p=1.0 or the image roughness when p=2.0. Constraints on the image, such as image positivity and estimated projection-data tolerance, are enforced by projection onto convex sets. The fact that the tomographic system is undersampled translates to the mathematical property that many widely varied resultant volumes may correspond to a given data tolerance. Thus the application of image regularity serves two purposes: (1) Reduction in the number of resultant volumes out of those allowed by fixing the data tolerance, finding the minimum image TpV for fixed data tolerance, and (2) traditional regularization, sacrificing data fidelity for higher image regularity. The present algorithm allows for this dual role of image regularity in undersampled tomography. Results: The proposed image-reconstruction algorithm is applied to three clinical DBT data sets. The DBT cases include one with microcalcifications and two with masses. Conclusions: Results indicate that there may be a substantial advantage in using the present image-reconstruction algorithm for microcalcification imaging.

  17. Optimization of PET image quality by means of 3D data acquisition and iterative image reconstruction

    International Nuclear Information System (INIS)

    Doll, J.; Zaers, J.; Trojan, H.; Bellemann, M.E.; Adam, L.E.; Haberkorn, U.; Brix, G.

    1998-01-01

    The experiments were performed at the latest-generation whole-body PET system ECAT EXACT HR + . For 2D data acquisition, a collimator of thin tungsten septa was positioned in the field-of-view. Prior to image reconstruction, the measured 3D data were sorted into 2D sinograms by using the Fourier rebinning (FORE) algorithm developed by M. Defrise. The standard filtered backprojection (FBP) method and an optimized ML/EM algorithm with overrelaxation for accelerated convergence were employed for image reconstruction. The spatial resolution of both methods as well as the convergence and noise properties of the ML/EM algorithm were studied in phantom measurements. Furthermore, patient data were acquired in the 2D mode as well as in the 3D mode and reconstructed with both techniques. At the same spatial resolution, the ML/EM-reconstructed images showed fewer and less prominent artefacts than the FBP-reconstructed images. The resulting improved detail conspicuously was achieved for the data acquired in the 2D mode as well as in the 3D mode. The best image quality was obtained by iterative 2D reconstruction of 3D data sets which were previously rebinned into 2D sinograms with help of the FORE algorithm. The phantom measurements revealed that 50 iteration steps with the otpimized ML/EM algorithm were sufficient to keep the relative quantitation error below 5%. (orig./MG) [de

  18. Specialized Color Targets for Spectral Reflectance Reconstruction of Magnified Images

    Science.gov (United States)

    Kruschwitz, Jennifer D. T.

    Digital images are used almost exclusively instead of film to capture visual information across many scientific fields. The colorimetric color representation within these digital images can be relayed from the digital counts produced by the camera with the use of a known color target. In image capture of magnified images, there is currently no reliable color target that can be used at multiple magnifications and give the user a solid understanding of the color ground truth within those images. The first part of this dissertation included the design, fabrication, and testing of a color target produced with optical interference coated microlenses for use in an off-axis illumination, compound microscope. An ideal target was designed to increase the color gamut for colorimetric imaging and provide the necessary "Block Dye" spectral reflectance profiles across the visible spectrum to reduce the number of color patches necessary for multiple filter imaging systems that rely on statistical models for spectral reflectance reconstruction. There are other scientific disciplines that can benefit from a specialized color target to determine the color ground truth in their magnified images and perform spectral estimation. Not every discipline has the luxury of having a multi-filter imaging system. The second part of this dissertation developed two unique ways of using an interference coated color mirror target: one that relies on multiple light-source angles, and one that leverages a dynamic color change with time. The source multi-angle technique would be used for the microelectronic discipline where the reconstructed spectral reflectance would be used to determine a dielectric film thickness on a silicon substrate, and the time varying technique would be used for a biomedical example to determine the thickness of human tear film.

  19. Fast nonconvex nonsmooth minimization methods for image restoration and reconstruction.

    Science.gov (United States)

    Nikolova, Mila; Ng, Michael K; Tam, Chi-Pan

    2010-12-01

    Nonconvex nonsmooth regularization has advantages over convex regularization for restoring images with neat edges. However, its practical interest used to be limited by the difficulty of the computational stage which requires a nonconvex nonsmooth minimization. In this paper, we deal with nonconvex nonsmooth minimization methods for image restoration and reconstruction. Our theoretical results show that the solution of the nonconvex nonsmooth minimization problem is composed of constant regions surrounded by closed contours and neat edges. The main goal of this paper is to develop fast minimization algorithms to solve the nonconvex nonsmooth minimization problem. Our experimental results show that the effectiveness and efficiency of the proposed algorithms.

  20. Task-based optimization of image reconstruction in breast CT

    Science.gov (United States)

    Sanchez, Adrian A.; Sidky, Emil Y.; Pan, Xiaochuan

    2014-03-01

    We demonstrate a task-based assessment of image quality in dedicated breast CT in order to optimize the number of projection views acquired. The methodology we employ is based on the Hotelling Observer (HO) and its associated metrics. We consider two tasks: the Rayleigh task of discerning between two resolvable objects and a single larger object, and the signal detection task of classifying an image as belonging to either a signalpresent or signal-absent hypothesis. HO SNR values are computed for 50, 100, 200, 500, and 1000 projection view images, with the total imaging radiation dose held constant. We use the conventional fan-beam FBP algorithm and investigate the effect of varying the width of a Hanning window used in the reconstruction, since this affects both the noise properties of the image and the under-sampling artifacts which can arise in the case of sparse-view acquisitions. Our results demonstrate that fewer projection views should be used in order to increase HO performance, which in this case constitutes an upper-bound on human observer performance. However, the impact on HO SNR of using fewer projection views, each with a higher dose, is not as significant as the impact of employing regularization in the FBP reconstruction through a Hanning filter.

  1. Multi-view Multi-sparsity Kernel Reconstruction for Multi-class Image Classification

    KAUST Repository

    Zhu, Xiaofeng; Xie, Qing; Zhu, Yonghua; Liu, Xingyi; Zhang, Shichao

    2015-01-01

    This paper addresses the problem of multi-class image classification by proposing a novel multi-view multi-sparsity kernel reconstruction (MMKR for short) model. Given images (including test images and training images) representing with multiple

  2. Effects of illumination on image reconstruction via Fourier ptychography

    Science.gov (United States)

    Cao, Xinrui; Sinzinger, Stefan

    2017-12-01

    The Fourier ptychographic microscopy (FPM) technique provides high-resolution images by combining a traditional imaging system, e.g. a microscope or a 4f-imaging system, with a multiplexing illumination system, e.g. an LED array and numerical image processing for enhanced image reconstruction. In order to numerically combine images that are captured under varying illumination angles, an iterative phase-retrieval algorithm is often applied. However, in practice, the performance of the FPM algorithm degrades due to the imperfections of the optical system, the image noise caused by the camera, etc. To eliminate the influence of the aberrations of the imaging system, an embedded pupil function recovery (EPRY)-FPM algorithm has been proposed [Opt. Express 22, 4960-4972 (2014)]. In this paper, we study how the performance of FPM and EPRY-FPM algorithms are affected by imperfections of the illumination system using both numerical simulations and experiments. The investigated imperfections include varying and non-uniform intensities, and wavefront aberrations. Our study shows that the aberrations of the illumination system significantly affect the performance of both FPM and EPRY-FPM algorithms. Hence, in practice, aberrations in the illumination system gain significant influence on the resulting image quality.

  3. Sub-Angstrom microscopy through incoherent imaging and image reconstruction

    International Nuclear Information System (INIS)

    Pennycook, S.J.; Jesson, D.E.; Chisholm, M.F.; Ferridge, A.G.; Seddon, M.J.

    1992-03-01

    Z-contrast scanning transmission electron microscopy (STEM) with a high-angle annular detector breaks the coherence of the imaging process, and provides an incoherent image of a crystal projection. Even in the presence of strong dynamical diffraction, the image can be accurately described as a convolution between an object function, sharply peaked at the projected atomic sites, and the probe intensity profile. Such an image can be inverted intuitively without the need for model structures, and therefore provides the important capability to reveal unanticipated interfacial arrangements. It represents a direct image of the crystal projection, revealing the location of the atomic columns and their relative high-angle scattering power. Since no phase is associated with a peak in the object function or the contrast transfer function, extension to higher resolution is also straightforward. Image restoration techniques such as maximum entropy, in conjunction with the 1.3 Angstrom probe anticipated for a 300 kV STEM, appear to provide a simple and robust route to the achievement of sub-Angstrom resolution electron microscopy

  4. Multiresolution 3-D reconstruction from side-scan sonar images.

    Science.gov (United States)

    Coiras, Enrique; Petillot, Yvan; Lane, David M

    2007-02-01

    In this paper, a new method for the estimation of seabed elevation maps from side-scan sonar images is presented. The side-scan image formation process is represented by a Lambertian diffuse model, which is then inverted by a multiresolution optimization procedure inspired by expectation-maximization to account for the characteristics of the imaged seafloor region. On convergence of the model, approximations for seabed reflectivity, side-scan beam pattern, and seabed altitude are obtained. The performance of the system is evaluated against a real structure of known dimensions. Reconstruction results for images acquired by different sonar sensors are presented. Applications to augmented reality for the simulation of targets in sonar imagery are also discussed.

  5. Qualitative and quantitative analysis of reconstructed images using projections with noises

    International Nuclear Information System (INIS)

    Lopes, R.T.; Assis, J.T. de

    1988-01-01

    The reconstruction of a two-dimencional image from one-dimensional projections in an analytic algorithm ''convolution method'' is simulated on a microcomputer. In this work it was analysed the effects caused in the reconstructed image in function of the number of projections and noise level added to the projection data. Qualitative and quantitative (distortion and image noise) comparison were done with the original image and the reconstructed images. (author) [pt

  6. Isotope specific resolution recovery image reconstruction in high resolution PET imaging

    Energy Technology Data Exchange (ETDEWEB)

    Kotasidis, Fotis A. [Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211 Geneva, Switzerland and Wolfson Molecular Imaging Centre, MAHSC, University of Manchester, M20 3LJ, Manchester (United Kingdom); Angelis, Georgios I. [Faculty of Health Sciences, Brain and Mind Research Institute, University of Sydney, NSW 2006, Sydney (Australia); Anton-Rodriguez, Jose; Matthews, Julian C. [Wolfson Molecular Imaging Centre, MAHSC, University of Manchester, Manchester M20 3LJ (United Kingdom); Reader, Andrew J. [Montreal Neurological Institute, McGill University, Montreal QC H3A 2B4, Canada and Department of Biomedical Engineering, Division of Imaging Sciences and Biomedical Engineering, King' s College London, St. Thomas’ Hospital, London SE1 7EH (United Kingdom); Zaidi, Habib [Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211 Geneva (Switzerland); Geneva Neuroscience Centre, Geneva University, CH-1205 Geneva (Switzerland); Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, PO Box 30 001, Groningen 9700 RB (Netherlands)

    2014-05-15

    Purpose: Measuring and incorporating a scanner-specific point spread function (PSF) within image reconstruction has been shown to improve spatial resolution in PET. However, due to the short half-life of clinically used isotopes, other long-lived isotopes not used in clinical practice are used to perform the PSF measurements. As such, non-optimal PSF models that do not correspond to those needed for the data to be reconstructed are used within resolution modeling (RM) image reconstruction, usually underestimating the true PSF owing to the difference in positron range. In high resolution brain and preclinical imaging, this effect is of particular importance since the PSFs become more positron range limited and isotope-specific PSFs can help maximize the performance benefit from using resolution recovery image reconstruction algorithms. Methods: In this work, the authors used a printing technique to simultaneously measure multiple point sources on the High Resolution Research Tomograph (HRRT), and the authors demonstrated the feasibility of deriving isotope-dependent system matrices from fluorine-18 and carbon-11 point sources. Furthermore, the authors evaluated the impact of incorporating them within RM image reconstruction, using carbon-11 phantom and clinical datasets on the HRRT. Results: The results obtained using these two isotopes illustrate that even small differences in positron range can result in different PSF maps, leading to further improvements in contrast recovery when used in image reconstruction. The difference is more pronounced in the centre of the field-of-view where the full width at half maximum (FWHM) from the positron range has a larger contribution to the overall FWHM compared to the edge where the parallax error dominates the overall FWHM. Conclusions: Based on the proposed methodology, measured isotope-specific and spatially variant PSFs can be reliably derived and used for improved spatial resolution and variance performance in resolution

  7. Isotope specific resolution recovery image reconstruction in high resolution PET imaging

    International Nuclear Information System (INIS)

    Kotasidis, Fotis A.; Angelis, Georgios I.; Anton-Rodriguez, Jose; Matthews, Julian C.; Reader, Andrew J.; Zaidi, Habib

    2014-01-01

    Purpose: Measuring and incorporating a scanner-specific point spread function (PSF) within image reconstruction has been shown to improve spatial resolution in PET. However, due to the short half-life of clinically used isotopes, other long-lived isotopes not used in clinical practice are used to perform the PSF measurements. As such, non-optimal PSF models that do not correspond to those needed for the data to be reconstructed are used within resolution modeling (RM) image reconstruction, usually underestimating the true PSF owing to the difference in positron range. In high resolution brain and preclinical imaging, this effect is of particular importance since the PSFs become more positron range limited and isotope-specific PSFs can help maximize the performance benefit from using resolution recovery image reconstruction algorithms. Methods: In this work, the authors used a printing technique to simultaneously measure multiple point sources on the High Resolution Research Tomograph (HRRT), and the authors demonstrated the feasibility of deriving isotope-dependent system matrices from fluorine-18 and carbon-11 point sources. Furthermore, the authors evaluated the impact of incorporating them within RM image reconstruction, using carbon-11 phantom and clinical datasets on the HRRT. Results: The results obtained using these two isotopes illustrate that even small differences in positron range can result in different PSF maps, leading to further improvements in contrast recovery when used in image reconstruction. The difference is more pronounced in the centre of the field-of-view where the full width at half maximum (FWHM) from the positron range has a larger contribution to the overall FWHM compared to the edge where the parallax error dominates the overall FWHM. Conclusions: Based on the proposed methodology, measured isotope-specific and spatially variant PSFs can be reliably derived and used for improved spatial resolution and variance performance in resolution

  8. Isotope specific resolution recovery image reconstruction in high resolution PET imaging.

    Science.gov (United States)

    Kotasidis, Fotis A; Angelis, Georgios I; Anton-Rodriguez, Jose; Matthews, Julian C; Reader, Andrew J; Zaidi, Habib

    2014-05-01

    Measuring and incorporating a scanner-specific point spread function (PSF) within image reconstruction has been shown to improve spatial resolution in PET. However, due to the short half-life of clinically used isotopes, other long-lived isotopes not used in clinical practice are used to perform the PSF measurements. As such, non-optimal PSF models that do not correspond to those needed for the data to be reconstructed are used within resolution modeling (RM) image reconstruction, usually underestimating the true PSF owing to the difference in positron range. In high resolution brain and preclinical imaging, this effect is of particular importance since the PSFs become more positron range limited and isotope-specific PSFs can help maximize the performance benefit from using resolution recovery image reconstruction algorithms. In this work, the authors used a printing technique to simultaneously measure multiple point sources on the High Resolution Research Tomograph (HRRT), and the authors demonstrated the feasibility of deriving isotope-dependent system matrices from fluorine-18 and carbon-11 point sources. Furthermore, the authors evaluated the impact of incorporating them within RM image reconstruction, using carbon-11 phantom and clinical datasets on the HRRT. The results obtained using these two isotopes illustrate that even small differences in positron range can result in different PSF maps, leading to further improvements in contrast recovery when used in image reconstruction. The difference is more pronounced in the centre of the field-of-view where the full width at half maximum (FWHM) from the positron range has a larger contribution to the overall FWHM compared to the edge where the parallax error dominates the overall FWHM. Based on the proposed methodology, measured isotope-specific and spatially variant PSFs can be reliably derived and used for improved spatial resolution and variance performance in resolution recovery image reconstruction. The

  9. Image-reconstruction algorithms for positron-emission tomography systems

    International Nuclear Information System (INIS)

    Cheng, S.N.C.

    1982-01-01

    The positional uncertainty in the time-of-flight measurement of a positron-emission tomography system is modelled as a Gaussian distributed random variable and the image is assumed to be piecewise constant on a rectilinear lattice. A reconstruction algorithm using maximum-likelihood estimation is derived for the situation in which time-of-flight data are sorted as the most-likely-position array. The algorithm is formulated as a linear system described by a nonseparable, block-banded, Toeplitz matrix, and a sine-transform technique is used to implement this algorithm efficiently. The reconstruction algorithms for both the most-likely-position array and the confidence-weighted array are described by similar equations, hence similar linear systems can be used to described the reconstruction algorithm for a discrete, confidence-weighted array, when the matrix and the entries in the data array are properly identified. It is found that the mean square-error depends on the ratio of the full width at half the maximum of time-of-flight measurement over the size of a pixel. When other parameters are fixed, the larger the pixel size, the smaller is the mean square-error. In the study of resolution, parameters that affect the impulse response of time-of-flight reconstruction algorithms are identified. It is found that the larger the pixel size, the larger is the standard deviation of the impulse response. This shows that small mean square-error and fine resolution are two contradictory requirements

  10. Structure Assisted Compressed Sensing Reconstruction of Undersampled AFM Images

    DEFF Research Database (Denmark)

    Oxvig, Christian Schou; Arildsen, Thomas; Larsen, Torben

    2017-01-01

    reconstruction algorithms that enables the use of our proposed structure model in the reconstruction process. Through a large set of reconstructions, the general reconstruction capability improvement achievable using our structured model is shown both quantitatively and qualitatively. Specifically, our...

  11. 3D surface reconstruction using optical flow for medical imaging

    International Nuclear Information System (INIS)

    Weng, Nan; Yang, Yee-Hong; Pierson, R.

    1996-01-01

    The recovery of a 3D model from a sequence of 2D images is very useful in medical image analysis. Image sequences obtained from the relative motion between the object and the camera or the scanner contain more 3D information than a single image. Methods to visualize the computed tomograms can be divided into two approaches: the surface rendering approach and the volume rendering approach. A new surface rendering method using optical flow is proposed. Optical flow is the apparent motion in the image plane produced by the projection of the real 3D motion onto 2D image. In this paper, the object remains stationary while the scanner undergoes translational motion. The 3D motion of an object can be recovered from the optical flow field using additional constraints. By extracting the surface information from 3D motion, it is possible to get an accurate 3D model of the object. Both synthetic and real image sequences have been used to illustrate the feasibility of the proposed method. The experimental results suggest that the proposed method is suitable for the reconstruction of 3D models from ultrasound medical images as well as other computed tomograms

  12. Simultaneous reconstruction and segmentation for dynamic SPECT imaging

    International Nuclear Information System (INIS)

    Burger, Martin; Rossmanith, Carolin; Zhang, Xiaoqun

    2016-01-01

    This work deals with the reconstruction of dynamic images that incorporate characteristic dynamics in certain subregions, as arising for the kinetics of many tracers in emission tomography (SPECT, PET). We make use of a basis function approach for the unknown tracer concentration by assuming that the region of interest can be divided into subregions with spatially constant concentration curves. Applying a regularised variational framework reminiscent of the Chan-Vese model for image segmentation we simultaneously reconstruct both the labelling functions of the subregions as well as the subconcentrations within each region. Our particular focus is on applications in SPECT with the Poisson noise model, resulting in a Kullback–Leibler data fidelity in the variational approach. We present a detailed analysis of the proposed variational model and prove existence of minimisers as well as error estimates. The latter apply to a more general class of problems and generalise existing results in literature since we deal with a nonlinear forward operator and a nonquadratic data fidelity. A computational algorithm based on alternating minimisation and splitting techniques is developed for the solution of the problem and tested on appropriately designed synthetic data sets. For those we compare the results to those of standard EM reconstructions and investigate the effects of Poisson noise in the data. (paper)

  13. Image reconstruction methods for the PBX-M pinhole camera

    International Nuclear Information System (INIS)

    Holland, A.; Powell, E.T.; Fonck, R.J.

    1990-03-01

    This paper describes two methods which have been used to reconstruct the soft x-ray emission profile of the PBX-M tokamak from the projected images recorded by the PBX-M pinhole camera. Both methods must accurately represent the shape of the reconstructed profile while also providing a degree of immunity to noise in the data. The first method is a simple least squares fit to the data. This has the advantage of being fast and small, and thus easily implemented on the PDP-11 computer used to control the video digitizer for the pinhole camera. The second method involves the application of a maximum entropy algorithm to an overdetermined system. This has the advantage of allowing the use of a default profile. This profile contains additional knowledge about the plasma shape which can be obtained from equilibrium fits to the external magnetic measurements. Additionally the reconstruction is guaranteed positive, and the fit to the data can be relaxed by specifying both the amount and distribution of noise in the image. The algorithm described has the advantage of being considerably faster, for an overdetermined system, than the usual Lagrange multiplier approach to finding the maximum entropy solution. 13 refs., 24 figs

  14. A filtering approach to image reconstruction in 3D SPECT

    International Nuclear Information System (INIS)

    Bronnikov, Andrei V.

    2000-01-01

    We present a new approach to three-dimensional (3D) image reconstruction using analytical inversion of the exponential divergent beam transform, which can serve as a mathematical model for cone-beam 3D SPECT imaging. We apply a circular cone-beam scan and assume constant attenuation inside a convex area with a known boundary, which is satisfactory in brain imaging. The reconstruction problem is reduced to an image restoration problem characterized by a shift-variant point spread function which is given analytically. The method requires two computation steps: backprojection and filtering. The modulation transfer function (MTF) of the filter is derived by means of an original methodology using the 2D Laplace transform. The filter is implemented in the frequency domain and requires 2D Fourier transform of transverse slices. In order to obtain a shift-invariant cone-beam projection-backprojection operator we resort to an approximation, assuming that the collimator has a relatively large focal length. Nevertheless, numerical experiments demonstrate surprisingly good results for detectors with relatively short focal lengths. The use of a wavelet-based filtering algorithm greatly improves the stability to Poisson noise. (author)

  15. Application of DIRI dynamic infrared imaging in reconstructive surgery

    Science.gov (United States)

    Pawlowski, Marek; Wang, Chengpu; Jin, Feng; Salvitti, Matthew; Tenorio, Xavier

    2006-04-01

    We have developed the BioScanIR System based on QWIP (Quantum Well Infrared Photodetector). Data collected by this sensor are processed using the DIRI (Dynamic Infrared Imaging) algorithms. The combination of DIRI data processing methods with the unique characteristics of the QWIP sensor permit the creation of a new imaging modality capable of detecting minute changes in temperature at the surface of the tissue and organs associated with blood perfusion due to certain diseases such as cancer, vascular disease and diabetes. The BioScanIR System has been successfully applied in reconstructive surgery to localize donor flap feeding vessels (perforators) during the pre-surgical planning stage. The device is also used in post-surgical monitoring of skin flap perfusion. Since the BioScanIR is mobile; it can be moved to the bedside for such monitoring. In comparison to other modalities, the BioScanIR can localize perforators in a single, 20 seconds scan with definitive results available in minutes. The algorithms used include (FFT) Fast Fourier Transformation, motion artifact correction, spectral analysis and thermal image scaling. The BioScanIR is completely non-invasive and non-toxic, requires no exogenous contrast agents and is free of ionizing radiation. In addition to reconstructive surgery applications, the BioScanIR has shown promise as a useful functional imaging modality in neurosurgery, drug discovery in pre-clinical animal models, wound healing and peripheral vascular disease management.

  16. Improved proton computed tomography by dual modality image reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, David C., E-mail: dch@ki.au.dk; Bassler, Niels [Experimental Clinical Oncology, Aarhus University, 8000 Aarhus C (Denmark); Petersen, Jørgen Breede Baltzer [Medical Physics, Aarhus University Hospital, 8000 Aarhus C (Denmark); Sørensen, Thomas Sangild [Computer Science, Aarhus University, 8000 Aarhus C, Denmark and Clinical Medicine, Aarhus University, 8200 Aarhus N (Denmark)

    2014-03-15

    Purpose: Proton computed tomography (CT) is a promising image modality for improving the stopping power estimates and dose calculations for particle therapy. However, the finite range of about 33 cm of water of most commercial proton therapy systems limits the sites that can be scanned from a full 360° rotation. In this paper the authors propose a method to overcome the problem using a dual modality reconstruction (DMR) combining the proton data with a cone-beam x-ray prior. Methods: A Catphan 600 phantom was scanned using a cone beam x-ray CT scanner. A digital replica of the phantom was created in the Monte Carlo code Geant4 and a 360° proton CT scan was simulated, storing the entrance and exit position and momentum vector of every proton. Proton CT images were reconstructed using a varying number of angles from the scan. The proton CT images were reconstructed using a constrained nonlinear conjugate gradient algorithm, minimizing total variation and the x-ray CT prior while remaining consistent with the proton projection data. The proton histories were reconstructed along curved cubic-spline paths. Results: The spatial resolution of the cone beam CT prior was retained for the fully sampled case and the 90° interval case, with the MTF = 0.5 (modulation transfer function) ranging from 5.22 to 5.65 linepairs/cm. In the 45° interval case, the MTF = 0.5 dropped to 3.91 linepairs/cm For the fully sampled DMR, the maximal root mean square (RMS) error was 0.006 in units of relative stopping power. For the limited angle cases the maximal RMS error was 0.18, an almost five-fold improvement over the cone beam CT estimate. Conclusions: Dual modality reconstruction yields the high spatial resolution of cone beam x-ray CT while maintaining the improved stopping power estimation of proton CT. In the case of limited angles, the use of prior image proton CT greatly improves the resolution and stopping power estimate, but does not fully achieve the quality of a 360

  17. Improved proton computed tomography by dual modality image reconstruction

    International Nuclear Information System (INIS)

    Hansen, David C.; Bassler, Niels; Petersen, Jørgen Breede Baltzer; Sørensen, Thomas Sangild

    2014-01-01

    Purpose: Proton computed tomography (CT) is a promising image modality for improving the stopping power estimates and dose calculations for particle therapy. However, the finite range of about 33 cm of water of most commercial proton therapy systems limits the sites that can be scanned from a full 360° rotation. In this paper the authors propose a method to overcome the problem using a dual modality reconstruction (DMR) combining the proton data with a cone-beam x-ray prior. Methods: A Catphan 600 phantom was scanned using a cone beam x-ray CT scanner. A digital replica of the phantom was created in the Monte Carlo code Geant4 and a 360° proton CT scan was simulated, storing the entrance and exit position and momentum vector of every proton. Proton CT images were reconstructed using a varying number of angles from the scan. The proton CT images were reconstructed using a constrained nonlinear conjugate gradient algorithm, minimizing total variation and the x-ray CT prior while remaining consistent with the proton projection data. The proton histories were reconstructed along curved cubic-spline paths. Results: The spatial resolution of the cone beam CT prior was retained for the fully sampled case and the 90° interval case, with the MTF = 0.5 (modulation transfer function) ranging from 5.22 to 5.65 linepairs/cm. In the 45° interval case, the MTF = 0.5 dropped to 3.91 linepairs/cm For the fully sampled DMR, the maximal root mean square (RMS) error was 0.006 in units of relative stopping power. For the limited angle cases the maximal RMS error was 0.18, an almost five-fold improvement over the cone beam CT estimate. Conclusions: Dual modality reconstruction yields the high spatial resolution of cone beam x-ray CT while maintaining the improved stopping power estimation of proton CT. In the case of limited angles, the use of prior image proton CT greatly improves the resolution and stopping power estimate, but does not fully achieve the quality of a 360

  18. Clinical applications of imaging reconstruction by virtual sonography

    International Nuclear Information System (INIS)

    Mori, Akihiro; Oohashi, Noritsugu; Maruyama, Takako; Tatebe, Hideharu; Fushimi, Nobutoshi; Asano, Takayuki; Inoue, Hiroshi; Okuno, Masataka

    2008-01-01

    One of the pitfalls in managing multiple liver tumors is the difficulty in identifying individual tumors on ultrasonography. Computed tomography (CT)-assisted virtual sonography has been shown to improve sonographic diagnosis, however it requires additional equipment and software. We have developed a simple reconstruction method of virtual sonography (SRVS). We reconstructed SRVS mimicking ultrasonographic images, utilizing a workstation software attached to a multi-detector row CT system without any additional program. We have performed SRVS in 32 patients with 41 liver tumors that could hardly be identify on ultrasonography. SRVS assisted the identification of malignant form non-pathologic ones and thereby contributed to the appropriate clinical strategy including radiofrequency ablation (RFA) (18 tumors), liver biopsy (2 tumors), other therapies (4 tumors) and follow-up (17 tumors). We have developed virtual sonography using conventional CT software. SRVS seems useful in the clinical practice in managing liver tumors. (author)

  19. Image reconstruction from multiple fan-beam projections

    International Nuclear Information System (INIS)

    Jelinek, J.; Overton, T.R.

    1984-01-01

    Special-purpose third-generation fan-beam CT systems can be greatly simplified by limiting the number of detectors, but this requires a different mode of data collection to provide a set of projections appropriate to the required spatial resolution in the reconstructed image. Repeated rotation of the source-detector fan, combined with shift of the detector array and perhaps offset of the source with respect to the fan's axis after each 360 0 rotation(cycle), provides a fairly general pattern of projection space filling. The authors' investigated the problem of optimal data-collection geometry for a multiple-rotation fan-beam scanner and of corresponding reconstruction algorithm

  20. Use of an object model in three dimensional image reconstruction. Application in medical imaging

    International Nuclear Information System (INIS)

    Delageniere-Guillot, S.

    1993-02-01

    Threedimensional image reconstruction from projections corresponds to a set of techniques which give information on the inner structure of the studied object. These techniques are mainly used in medical imaging or in non destructive evaluation. Image reconstruction is an ill-posed problem. So the inversion has to be regularized. This thesis deals with the introduction of a priori information within the reconstruction algorithm. The knowledge is introduced through an object model. The proposed scheme is applied to the medical domain for cone beam geometry. We address two specific problems. First, we study the reconstruction of high contrast objects. This can be applied to bony morphology (bone/soft tissue) or to angiography (vascular structures opacified by injection of contrast agent). With noisy projections, the filtering steps of standard methods tend to smooth the natural transitions of the investigated object. In order to regularize the reconstruction but to keep contrast, we introduce a model of classes which involves the Markov random fields theory. We develop a reconstruction scheme: analytic reconstruction-reprojection. Then, we address the case of an object changing during the acquisition. This can be applied to angiography when the contrast agent is moving through the vascular tree. The problem is then stated as a dynamic reconstruction. We define an evolution AR model and we use an algebraic reconstruction method. We represent the object at a particular moment as an intermediary state between the state of the object at the beginning and at the end of the acquisition. We test both methods on simulated and real data, and we prove how the use of an a priori model can improve the results. (author)

  1. Effect of filters and reconstruction algorithms on I-124 PET in Siemens Inveon PET scanner

    Science.gov (United States)

    Ram Yu, A.; Kim, Jin Su

    2015-10-01

    Purpose: To assess the effects of filtering and reconstruction on Siemens I-124 PET data. Methods: A Siemens Inveon PET was used. Spatial resolution of I-124 was measured to a transverse offset of 50 mm from the center FBP, 2D ordered subset expectation maximization (OSEM2D), 3D re-projection algorithm (3DRP), and maximum a posteriori (MAP) methods were tested. Non-uniformity (NU), recovery coefficient (RC), and spillover ratio (SOR) parameterized image quality. Mini deluxe phantom data of I-124 was also assessed. Results: Volumetric resolution was 7.3 mm3 from the transverse FOV center when FBP reconstruction algorithms with ramp filter was used. MAP yielded minimal NU with β =1.5. OSEM2D yielded maximal RC. SOR was below 4% for FBP with ramp, Hamming, Hanning, or Shepp-Logan filters. Based on the mini deluxe phantom results, an FBP with Hanning or Parzen filters, or a 3DRP with Hanning filter yielded feasible I-124 PET data.Conclusions: Reconstruction algorithms and filters were compared. FBP with Hanning or Parzen filters, or 3DRP with Hanning filter yielded feasible data for quantifying I-124 PET.

  2. The effect of filtrating and reconstruction method on the left ventricular ejection fraction derived from GSPET. A statistical comparison of angiography and echocardiography

    International Nuclear Information System (INIS)

    Bitarafan, A.; Rajabi, H.

    2008-01-01

    There are different protocols of reconstruction in myocardial gated imaging that produce different values of left ventricular ejection fraction (EF). We attempted to determine how the parameters of reconstruction affect the calculated EF. The results were statistically compared with the values obtained from angiography and echocardiography. In this retrospective study, the data from 23 patients were used. All the patients had the angiographic and the echocardiographic data within 2 weeks before the test. Imaging was performed using a single-head gamma camera using technetium-99 methoxyisobutylisonitrile. The image data were reconstructed using 50 different combinations of the ramp, Hanning, Butterworth, Wiener, and Metz filters. The ordered subset expectation maximization (OSEM) technique was also examined using 12 combinations of iteration and subset. The calculated EF values were analyzed and compared with the echocardiographic and angiographic results. The backprojection technique produced higher values of EF than those derived from echocardiography and angiography. The OSEM on the other hand produced lower values when compared with echocardiography and angiography. On using the backprojection technique, the maximum correlation between the values derived from gated single-photon emission tomography and echocardiography (r=0.88, P<0.01) and angiography (r=0.81, P<0.01) was observed when using the Metz filter (full width at half maximum=5 mm and order=9) and the Gaussian filter (α=3), respectively. In the case of the OSEM technique, the maximum correlation with both angiography and echocardiography was observed when using the iteration=2 and the subset=12. On the average, the backprojection technique produces higher values, and iteration technique produces lower estimation of the EF when compared with angiography and echocardiography. (author)

  3. Level-set-based reconstruction algorithm for EIT lung images: first clinical results.

    Science.gov (United States)

    Rahmati, Peyman; Soleimani, Manuchehr; Pulletz, Sven; Frerichs, Inéz; Adler, Andy

    2012-05-01

    We show the first clinical results using the level-set-based reconstruction algorithm for electrical impedance tomography (EIT) data. The level-set-based reconstruction method (LSRM) allows the reconstruction of non-smooth interfaces between image regions, which are typically smoothed by traditional voxel-based reconstruction methods (VBRMs). We develop a time difference formulation of the LSRM for 2D images. The proposed reconstruction method is applied to reconstruct clinical EIT data of a slow flow inflation pressure-volume manoeuvre in lung-healthy and adult lung-injury patients. Images from the LSRM and the VBRM are compared. The results show comparable reconstructed images, but with an improved ability to reconstruct sharp conductivity changes in the distribution of lung ventilation using the LSRM.

  4. Level-set-based reconstruction algorithm for EIT lung images: first clinical results

    International Nuclear Information System (INIS)

    Rahmati, Peyman; Adler, Andy; Soleimani, Manuchehr; Pulletz, Sven; Frerichs, Inéz

    2012-01-01

    We show the first clinical results using the level-set-based reconstruction algorithm for electrical impedance tomography (EIT) data. The level-set-based reconstruction method (LSRM) allows the reconstruction of non-smooth interfaces between image regions, which are typically smoothed by traditional voxel-based reconstruction methods (VBRMs). We develop a time difference formulation of the LSRM for 2D images. The proposed reconstruction method is applied to reconstruct clinical EIT data of a slow flow inflation pressure–volume manoeuvre in lung-healthy and adult lung-injury patients. Images from the LSRM and the VBRM are compared. The results show comparable reconstructed images, but with an improved ability to reconstruct sharp conductivity changes in the distribution of lung ventilation using the LSRM. (paper)

  5. Fast MR image reconstruction for partially parallel imaging with arbitrary k-space trajectories.

    Science.gov (United States)

    Ye, Xiaojing; Chen, Yunmei; Lin, Wei; Huang, Feng

    2011-03-01

    Both acquisition and reconstruction speed are crucial for magnetic resonance (MR) imaging in clinical applications. In this paper, we present a fast reconstruction algorithm for SENSE in partially parallel MR imaging with arbitrary k-space trajectories. The proposed method is a combination of variable splitting, the classical penalty technique and the optimal gradient method. Variable splitting and the penalty technique reformulate the SENSE model with sparsity regularization as an unconstrained minimization problem, which can be solved by alternating two simple minimizations: One is the total variation and wavelet based denoising that can be quickly solved by several recent numerical methods, whereas the other one involves a linear inversion which is solved by the optimal first order gradient method in our algorithm to significantly improve the performance. Comparisons with several recent parallel imaging algorithms indicate that the proposed method significantly improves the computation efficiency and achieves state-of-the-art reconstruction quality.

  6. Optimization of Rb-82 PET acquisition and reconstruction protocols for myocardial perfusion defect detection

    Science.gov (United States)

    Tang, Jing; Rahmim, Arman; Lautamäki, Riikka; Lodge, Martin A.; Bengel, Frank M.; Tsui, Benjamin M. W.

    2009-05-01

    The purpose of this study is to optimize the dynamic Rb-82 cardiac PET acquisition and reconstruction protocols for maximum myocardial perfusion defect detection using realistic simulation data and task-based evaluation. Time activity curves (TACs) of different organs under both rest and stress conditions were extracted from dynamic Rb-82 PET images of five normal patients. Combined SimSET-GATE Monte Carlo simulation was used to generate nearly noise-free cardiac PET data from a time series of 3D NCAT phantoms with organ activities modeling different pre-scan delay times (PDTs) and total acquisition times (TATs). Poisson noise was added to the nearly noise-free projections and the OS-EM algorithm was applied to generate noisy reconstructed images. The channelized Hotelling observer (CHO) with 32× 32 spatial templates corresponding to four octave-wide frequency channels was used to evaluate the images. The area under the ROC curve (AUC) was calculated from the CHO rating data as an index for image quality in terms of myocardial perfusion defect detection. The 0.5 cycle cm-1 Butterworth post-filtering on OS-EM (with 21 subsets) reconstructed images generates the highest AUC values while those from iteration numbers 1 to 4 do not show different AUC values. The optimized PDTs for both rest and stress conditions are found to be close to the cross points of the left ventricular chamber and myocardium TACs, which may promote an individualized PDT for patient data processing and image reconstruction. Shortening the TATs for <~3 min from the clinically employed acquisition time does not affect the myocardial perfusion defect detection significantly for both rest and stress studies.

  7. Sparse/Low Rank Constrained Reconstruction for Dynamic PET Imaging.

    Directory of Open Access Journals (Sweden)

    Xingjian Yu

    Full Text Available In dynamic Positron Emission Tomography (PET, an estimate of the radio activity concentration is obtained from a series of frames of sinogram data taken at ranging in duration from 10 seconds to minutes under some criteria. So far, all the well-known reconstruction algorithms require known data statistical properties. It limits the speed of data acquisition, besides, it is unable to afford the separated information about the structure and the variation of shape and rate of metabolism which play a major role in improving the visualization of contrast for some requirement of the diagnosing in application. This paper presents a novel low rank-based activity map reconstruction scheme from emission sinograms of dynamic PET, termed as SLCR representing Sparse/Low Rank Constrained Reconstruction for Dynamic PET Imaging. In this method, the stationary background is formulated as a low rank component while variations between successive frames are abstracted to the sparse. The resulting nuclear norm and l1 norm related minimization problem can also be efficiently solved by many recently developed numerical methods. In this paper, the linearized alternating direction method is applied. The effectiveness of the proposed scheme is illustrated on three data sets.

  8. Quantitative image reconstruction for total-body PET imaging using the 2-meter long EXPLORER scanner

    Science.gov (United States)

    Zhang, Xuezhu; Zhou, Jian; Cherry, Simon R.; Badawi, Ramsey D.; Qi, Jinyi

    2017-03-01

    The EXPLORER project aims to build a 2 meter long total-body PET scanner, which will provide extremely high sensitivity for imaging the entire human body. It will possess a range of capabilities currently unavailable to state-of-the-art clinical PET scanners with a limited axial field-of-view. The huge number of lines-of-response (LORs) of the EXPLORER poses a challenge to the data handling and image reconstruction. The objective of this study is to develop a quantitative image reconstruction method for the EXPLORER and compare its performance with current whole-body scanners. Fully 3D image reconstruction was performed using time-of-flight list-mode data with parallel computation. To recover the resolution loss caused by the parallax error between crystal pairs at a large axial ring difference or transaxial radial offset, we applied an image domain resolution model estimated from point source data. To evaluate the image quality, we conducted computer simulations using the SimSET Monte-Carlo toolkit and XCAT 2.0 anthropomorphic phantom to mimic a 20 min whole-body PET scan with an injection of 25 MBq 18F-FDG. We compare the performance of the EXPLORER with a current clinical scanner that has an axial FOV of 22 cm. The comparison results demonstrated superior image quality from the EXPLORER with a 6.9-fold reduction in noise standard deviation comparing with multi-bed imaging using the clinical scanner.

  9. Evaluation of imaging protocol for ECT based on CS image reconstruction algorithm

    International Nuclear Information System (INIS)

    Zhou Xiaolin; Yun Mingkai; Cao Xuexiang; Liu Shuangquan; Wang Lu; Huang Xianchao; Wei Long

    2014-01-01

    Single-photon emission computerized tomography and positron emission tomography are essential medical imaging tools, for which the sampling angle number and scan time should be carefully chosen to give a good compromise between image quality and radiopharmaceutical dose. In this study, the image quality of different acquisition protocols was evaluated via varied angle number and count number per angle with Monte Carlo simulation data. It was shown that, when similar imaging counts were used, the factor of acquisition counts was more important than that of the sampling number in emission computerized tomography. To further reduce the activity requirement and the scan duration, an iterative image reconstruction algorithm for limited-view and low-dose tomography based on compressed sensing theory has been developed. The total variation regulation was added to the reconstruction process to improve the signal to noise Ratio and reduce artifacts caused by the limited angle sampling. Maximization of the maximum likelihood of the estimated image and the measured data and minimization of the total variation of the image are alternatively implemented. By using this advanced algorithm, the reconstruction process is able to achieve image quality matching or exceed that of normal scans with only half of the injection radiopharmaceutical dose. (authors)

  10. Reconstruction algorithm medical imaging DRR; Algoritmo de construccion de imagenes medicas DRR

    Energy Technology Data Exchange (ETDEWEB)

    Estrada Espinosa, J. C.

    2013-07-01

    The method of reconstruction for digital radiographic Imaging (DRR), is based on two orthogonal images, on the dorsal and lateral decubitus position of the simulation. DRR images are reconstructed with an algorithm that simulates running a conventional X-ray, a single rendition team, beam emitted is not divergent, in this case, the rays are considered to be parallel in the image reconstruction DRR, for this purpose, it is necessary to use all the values of the units (HU) hounsfield of each voxel in all axial cuts that form the study TC, finally obtaining the reconstructed image DRR performing a transformation from 3D to 2D. (Author)

  11. Accelerating image reconstruction in three-dimensional optoacoustic tomography on graphics processing units.

    Science.gov (United States)

    Wang, Kun; Huang, Chao; Kao, Yu-Jiun; Chou, Cheng-Ying; Oraevsky, Alexander A; Anastasio, Mark A

    2013-02-01

    Optoacoustic tomography (OAT) is inherently a three-dimensional (3D) inverse problem. However, most studies of OAT image reconstruction still employ two-dimensional imaging models. One important reason is because 3D image reconstruction is computationally burdensome. The aim of this work is to accelerate existing image reconstruction algorithms for 3D OAT by use of parallel programming techniques. Parallelization strategies are proposed to accelerate a filtered backprojection (FBP) algorithm and two different pairs of projection/backprojection operations that correspond to two different numerical imaging models. The algorithms are designed to fully exploit the parallel computing power of graphics processing units (GPUs). In order to evaluate the parallelization strategies for the projection/backprojection pairs, an iterative image reconstruction algorithm is implemented. Computer simulation and experimental studies are conducted to investigate the computational efficiency and numerical accuracy of the developed algorithms. The GPU implementations improve the computational efficiency by factors of 1000, 125, and 250 for the FBP algorithm and the two pairs of projection/backprojection operators, respectively. Accurate images are reconstructed by use of the FBP and iterative image reconstruction algorithms from both computer-simulated and experimental data. Parallelization strategies for 3D OAT image reconstruction are proposed for the first time. These GPU-based implementations significantly reduce the computational time for 3D image reconstruction, complementing our earlier work on 3D OAT iterative image reconstruction.

  12. Maximum entropy reconstructions for crystallographic imaging; Cristallographie et reconstruction d`images par maximum d`entropie

    Energy Technology Data Exchange (ETDEWEB)

    Papoular, R

    1997-07-01

    The Fourier Transform is of central importance to Crystallography since it allows the visualization in real space of tridimensional scattering densities pertaining to physical systems from diffraction data (powder or single-crystal diffraction, using x-rays, neutrons, electrons or else). In turn, this visualization makes it possible to model and parametrize these systems, the crystal structures of which are eventually refined by Least-Squares techniques (e.g., the Rietveld method in the case of Powder Diffraction). The Maximum Entropy Method (sometimes called MEM or MaxEnt) is a general imaging technique, related to solving ill-conditioned inverse problems. It is ideally suited for tackling undetermined systems of linear questions (for which the number of variables is much larger than the number of equations). It is already being applied successfully in Astronomy, Radioastronomy and Medical Imaging. The advantages of using MAXIMUM Entropy over conventional Fourier and `difference Fourier` syntheses stem from the following facts: MaxEnt takes the experimental error bars into account; MaxEnt incorporate Prior Knowledge (e.g., the positivity of the scattering density in some instances); MaxEnt allows density reconstructions from incompletely phased data, as well as from overlapping Bragg reflections; MaxEnt substantially reduces truncation errors to which conventional experimental Fourier reconstructions are usually prone. The principles of Maximum Entropy imaging as applied to Crystallography are first presented. The method is then illustrated by a detailed example specific to Neutron Diffraction: the search for proton in solids. (author). 17 refs.

  13. Computed Tomography Image Quality Evaluation of a New Iterative Reconstruction Algorithm in the Abdomen (Adaptive Statistical Iterative Reconstruction-V) a Comparison With Model-Based Iterative Reconstruction, Adaptive Statistical Iterative Reconstruction, and Filtered Back Projection Reconstructions.

    Science.gov (United States)

    Goodenberger, Martin H; Wagner-Bartak, Nicolaus A; Gupta, Shiva; Liu, Xinming; Yap, Ramon Q; Sun, Jia; Tamm, Eric P; Jensen, Corey T

    The purpose of this study was to compare abdominopelvic computed tomography images reconstructed with adaptive statistical iterative reconstruction-V (ASIR-V) with model-based iterative reconstruction (Veo 3.0), ASIR, and filtered back projection (FBP). Abdominopelvic computed tomography scans for 36 patients (26 males and 10 females) were reconstructed using FBP, ASIR (80%), Veo 3.0, and ASIR-V (30%, 60%, 90%). Mean ± SD patient age was 32 ± 10 years with mean ± SD body mass index of 26.9 ± 4.4 kg/m. Images were reviewed by 2 independent readers in a blinded, randomized fashion. Hounsfield unit, noise, and contrast-to-noise ratio (CNR) values were calculated for each reconstruction algorithm for further comparison. Phantom evaluation of low-contrast detectability (LCD) and high-contrast resolution was performed. Adaptive statistical iterative reconstruction-V 30%, ASIR-V 60%, and ASIR 80% were generally superior qualitatively compared with ASIR-V 90%, Veo 3.0, and FBP (P ASIR-V 60% with respective CNR values of 5.54 ± 2.39, 8.78 ± 3.15, and 3.49 ± 1.77 (P ASIR 80% had the best and worst spatial resolution, respectively. Adaptive statistical iterative reconstruction-V 30% and ASIR-V 60% provided the best combination of qualitative and quantitative performance. Adaptive statistical iterative reconstruction 80% was equivalent qualitatively, but demonstrated inferior spatial resolution and LCD.

  14. Reconstruction, Processing and Display of 3D-Images

    International Nuclear Information System (INIS)

    Lenz, R.

    1986-01-01

    In the last few years a number of methods have been developed which can produce true 3D images, volumes of density values. We review two of these techniques (confocal microscopy and X-ray tomography) which were used in the reconstruction of some of our images. The other images came from transmission electron microscopes, gammacameras and magnetic resonance scanners. A new algorithm is suggested which uses projection onto convex sets to improve the depth resolution in the microscopy case. Since we use a TV-monitor as display device we have to project 3D volumes to 2D images. We use the following type of projections: reprojections, range images, colorcoded depth and shaded surface displays. Shaded surface displays use the surface gradient to compute the gray value in the projection. We describe how this gradient can be computed from the range image and from the original density volume. Normally we compute a whole series of projections where the volume is rotated some degrees between two projections. In a separate display session we can display these images in stereo and motion. We describe how noise reduction filters, gray value transformations, geometric manipulations, gradient filters, texture filters and binary techniques can be used to remove uninteresting points from the volume. Finally, a filter design strategy is developed which is based on the optimal basis function approach by Hummel. We show that for a large class of patterns, in images of arbitrary dimensions, the optimal basis functions are rotation-invariant operators as introduced by Danielsson in the 2D case. We also describe how the orientation of a pattern can be computed from its feature vector. (With 107 refs.) (author)

  15. Poisson image reconstruction with Hessian Schatten-norm regularization.

    Science.gov (United States)

    Lefkimmiatis, Stamatios; Unser, Michael

    2013-11-01

    Poisson inverse problems arise in many modern imaging applications, including biomedical and astronomical ones. The main challenge is to obtain an estimate of the underlying image from a set of measurements degraded by a linear operator and further corrupted by Poisson noise. In this paper, we propose an efficient framework for Poisson image reconstruction, under a regularization approach, which depends on matrix-valued regularization operators. In particular, the employed regularizers involve the Hessian as the regularization operator and Schatten matrix norms as the potential functions. For the solution of the problem, we propose two optimization algorithms that are specifically tailored to the Poisson nature of the noise. These algorithms are based on an augmented-Lagrangian formulation of the problem and correspond to two variants of the alternating direction method of multipliers. Further, we derive a link that relates the proximal map of an l(p) norm with the proximal map of a Schatten matrix norm of order p. This link plays a key role in the development of one of the proposed algorithms. Finally, we provide experimental results on natural and biological images for the task of Poisson image deblurring and demonstrate the practical relevance and effectiveness of the proposed framework.

  16. Accelerated Computing in Magnetic Resonance Imaging: Real-Time Imaging Using Nonlinear Inverse Reconstruction

    Directory of Open Access Journals (Sweden)

    Sebastian Schaetz

    2017-01-01

    Full Text Available Purpose. To develop generic optimization strategies for image reconstruction using graphical processing units (GPUs in magnetic resonance imaging (MRI and to exemplarily report on our experience with a highly accelerated implementation of the nonlinear inversion (NLINV algorithm for dynamic MRI with high frame rates. Methods. The NLINV algorithm is optimized and ported to run on a multi-GPU single-node server. The algorithm is mapped to multiple GPUs by decomposing the data domain along the channel dimension. Furthermore, the algorithm is decomposed along the temporal domain by relaxing a temporal regularization constraint, allowing the algorithm to work on multiple frames in parallel. Finally, an autotuning method is presented that is capable of combining different decomposition variants to achieve optimal algorithm performance in different imaging scenarios. Results. The algorithm is successfully ported to a multi-GPU system and allows online image reconstruction with high frame rates. Real-time reconstruction with low latency and frame rates up to 30 frames per second is demonstrated. Conclusion. Novel parallel decomposition methods are presented which are applicable to many iterative algorithms for dynamic MRI. Using these methods to parallelize the NLINV algorithm on multiple GPUs, it is possible to achieve online image reconstruction with high frame rates.

  17. Model-based image reconstruction for four-dimensional PET

    International Nuclear Information System (INIS)

    Li Tianfang; Thorndyke, Brian; Schreibmann, Eduard; Yang Yong; Xing Lei

    2006-01-01

    Positron emission tonography (PET) is useful in diagnosis and radiation treatment planning for a variety of cancers. For patients with cancers in thoracic or upper abdominal region, the respiratory motion produces large distortions in the tumor shape and size, affecting the accuracy in both diagnosis and treatment. Four-dimensional (4D) (gated) PET aims to reduce the motion artifacts and to provide accurate measurement of the tumor volume and the tracer concentration. A major issue in 4D PET is the lack of statistics. Since the collected photons are divided into several frames in the 4D PET scan, the quality of each reconstructed frame degrades as the number of frames increases. The increased noise in each frame heavily degrades the quantitative accuracy of the PET imaging. In this work, we propose a method to enhance the performance of 4D PET by developing a new technique of 4D PET reconstruction with incorporation of an organ motion model derived from 4D-CT images. The method is based on the well-known maximum-likelihood expectation-maximization (ML-EM) algorithm. During the processes of forward- and backward-projection in the ML-EM iterations, all projection data acquired at different phases are combined together to update the emission map with the aid of deformable model, the statistics is therefore greatly improved. The proposed algorithm was first evaluated with computer simulations using a mathematical dynamic phantom. Experiment with a moving physical phantom was then carried out to demonstrate the accuracy of the proposed method and the increase of signal-to-noise ratio over three-dimensional PET. Finally, the 4D PET reconstruction was applied to a patient case

  18. Compositional-prior-guided image reconstruction algorithm for multi-modality imaging

    Science.gov (United States)

    Fang, Qianqian; Moore, Richard H.; Kopans, Daniel B.; Boas, David A.

    2010-01-01

    The development of effective multi-modality imaging methods typically requires an efficient information fusion model, particularly when combining structural images with a complementary imaging modality that provides functional information. We propose a composition-based image segmentation method for X-ray digital breast tomosynthesis (DBT) and a structural-prior-guided image reconstruction for a combined DBT and diffuse optical tomography (DOT) breast imaging system. Using the 3D DBT images from 31 clinically measured healthy breasts, we create an empirical relationship between the X-ray intensities for adipose and fibroglandular tissue. We use this relationship to then segment another 58 healthy breast DBT images from 29 subjects into compositional maps of different tissue types. For each breast, we build a weighted-graph in the compositional space and construct a regularization matrix to incorporate the structural priors into a finite-element-based DOT image reconstruction. Use of the compositional priors enables us to fuse tissue anatomy into optical images with less restriction than when using a binary segmentation. This allows us to recover the image contrast captured by DOT but not by DBT. We show that it is possible to fine-tune the strength of the structural priors by changing a single regularization parameter. By estimating the optical properties for adipose and fibroglandular tissue using the proposed algorithm, we found the results are comparable or superior to those estimated with expert-segmentations, but does not involve the time-consuming manual selection of regions-of-interest. PMID:21258460

  19. Image Reconstruction and Evaluation: Applications on Micro-Surfaces and Lenna Image Representation

    Directory of Open Access Journals (Sweden)

    Mohammad Mayyas

    2016-09-01

    Full Text Available This article develops algorithms for the characterization and the visualization of micro-scale features using a small number of sample points, with the goal of mitigating the measurement shortcomings, which are often destructive or time consuming. The popular measurement techniques that are used in imaging of micro-surfaces include the 3D stylus or interferometric profilometry and Scanning Electron Microscopy (SEM, where both could represent the micro-surface characteristics in terms of 3D dimensional topology and greyscale image, respectively. Such images could be highly dense; therefore, traditional image processing techniques might be computationally expensive. We implement the algorithms in several case studies to rapidly examine the microscopic features of micro-surface of Microelectromechanical System (MEMS, and then we validate the results using a popular greyscale image; i.e., “Lenna” image. The contributions of this research include: First, development of local and global algorithm based on modified Thin Plate Spline (TPS model to reconstruct high resolution images of the micro-surface’s topography, and its derivatives using low resolution images. Second, development of a bending energy algorithm from our modified TPS model for filtering out image defects. Finally, development of a computationally efficient technique, referred to as Windowing, which combines TPS and Linear Sequential Estimation (LSE methods, to enhance the visualization of images. The Windowing technique allows rapid image reconstruction based on the reduction of inverse problem.

  20. An Optimized Method for Terrain Reconstruction Based on Descent Images

    Directory of Open Access Journals (Sweden)

    Xu Xinchao

    2016-02-01

    Full Text Available An optimization method is proposed to perform high-accuracy terrain reconstruction of the landing area of Chang’e III. First, feature matching is conducted using geometric model constraints. Then, the initial terrain is obtained and the initial normal vector of each point is solved on the basis of the initial terrain. By changing the vector around the initial normal vector in small steps a set of new vectors is obtained. By combining these vectors with the direction of light and camera, the functions are set up on the basis of a surface reflection model. Then, a series of gray values is derived by solving the equations. The new optimized vector is recorded when the obtained gray value is closest to the corresponding pixel. Finally, the optimized terrain is obtained after iteration of the vector field. Experiments were conducted using the laboratory images and descent images of Chang’e III. The results showed that the performance of the proposed method was better than that of the classical feature matching method. It can provide a reference for terrain reconstruction of the landing area in subsequent moon exploration missions.

  1. Iterative feature refinement for accurate undersampled MR image reconstruction

    Science.gov (United States)

    Wang, Shanshan; Liu, Jianbo; Liu, Qiegen; Ying, Leslie; Liu, Xin; Zheng, Hairong; Liang, Dong

    2016-05-01

    Accelerating MR scan is of great significance for clinical, research and advanced applications, and one main effort to achieve this is the utilization of compressed sensing (CS) theory. Nevertheless, the existing CSMRI approaches still have limitations such as fine structure loss or high computational complexity. This paper proposes a novel iterative feature refinement (IFR) module for accurate MR image reconstruction from undersampled K-space data. Integrating IFR with CSMRI which is equipped with fixed transforms, we develop an IFR-CS method to restore meaningful structures and details that are originally discarded without introducing too much additional complexity. Specifically, the proposed IFR-CS is realized with three iterative steps, namely sparsity-promoting denoising, feature refinement and Tikhonov regularization. Experimental results on both simulated and in vivo MR datasets have shown that the proposed module has a strong capability to capture image details, and that IFR-CS is comparable and even superior to other state-of-the-art reconstruction approaches.

  2. Iterative feature refinement for accurate undersampled MR image reconstruction

    International Nuclear Information System (INIS)

    Wang, Shanshan; Liu, Jianbo; Liu, Xin; Zheng, Hairong; Liang, Dong; Liu, Qiegen; Ying, Leslie

    2016-01-01

    Accelerating MR scan is of great significance for clinical, research and advanced applications, and one main effort to achieve this is the utilization of compressed sensing (CS) theory. Nevertheless, the existing CSMRI approaches still have limitations such as fine structure loss or high computational complexity. This paper proposes a novel iterative feature refinement (IFR) module for accurate MR image reconstruction from undersampled K-space data. Integrating IFR with CSMRI which is equipped with fixed transforms, we develop an IFR-CS method to restore meaningful structures and details that are originally discarded without introducing too much additional complexity. Specifically, the proposed IFR-CS is realized with three iterative steps, namely sparsity-promoting denoising, feature refinement and Tikhonov regularization. Experimental results on both simulated and in vivo MR datasets have shown that the proposed module has a strong capability to capture image details, and that IFR-CS is comparable and even superior to other state-of-the-art reconstruction approaches. (paper)

  3. MR imaging of the augmented and reconstructed breast

    International Nuclear Information System (INIS)

    Ivanov, V.; Kirova, G.

    2013-01-01

    Full text: Introduction: Various diagnostic methods are used to assess the changes in both the integrity of the implant, and the fibrous capsule of breast parenchyma. MRI has advantages over other diagnostic methods providing high tissue contrast, multi-faceted imaging and lack of ionizing radiation. What you will learn: MRI evaluation of breast augmentation approaches and their complications, MRI assessment of disease with malignant and benign characteristics in patients with breast implants, MRI assessment of breast reconstruction with autologous tissue. Discussion: Mammography after augmentation and reconstructive mammoplasty is hampered by the deformation of the breast parenchyma of the implant and the reduced compression. Postoperative scarring is also difficult to assess. MRI evaluation of implant rupture is accurate using the findings specific to it - linguine sign, teardrop sign or siliconomas. According to Gorczyca et al. MRI has a sensitivity 94% and specificity 97% in the evaluation of rupture. MRI mammography is highly sensitive - between 90 and 95%, in the detection of malignant, but it has limited specificity, which is its disadvantage. Malignant lesions can be represented as fibroadenomas, postoperative and inflammatory changes. Conclusion: Difficulties in the diagnosis of rupture of the implant, the primary and recurrent carcinoma based on clinical examination and inconclusive data from mammography and ultrasound imaging make MRI the method of choice in the evaluation of patients with breast implants

  4. A Convex Formulation for Magnetic Particle Imaging X-Space Reconstruction.

    Science.gov (United States)

    Konkle, Justin J; Goodwill, Patrick W; Hensley, Daniel W; Orendorff, Ryan D; Lustig, Michael; Conolly, Steven M

    2015-01-01

    Magnetic Particle Imaging (mpi) is an emerging imaging modality with exceptional promise for clinical applications in rapid angiography, cell therapy tracking, cancer imaging, and inflammation imaging. Recent publications have demonstrated quantitative mpi across rat sized fields of view with x-space reconstruction methods. Critical to any medical imaging technology is the reliability and accuracy of image reconstruction. Because the average value of the mpi signal is lost during direct-feedthrough signal filtering, mpi reconstruction algorithms must recover this zero-frequency value. Prior x-space mpi recovery techniques were limited to 1d approaches which could introduce artifacts when reconstructing a 3d image. In this paper, we formulate x-space reconstruction as a 3d convex optimization problem and apply robust a priori knowledge of image smoothness and non-negativity to reduce non-physical banding and haze artifacts. We conclude with a discussion of the powerful extensibility of the presented formulation for future applications.

  5. Fully three-dimensional image reconstruction in radiology and nuclear medicine. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The proceedings of the meeting on ''fully three-dimensional image reconstruction in radiology and nuclear medicine'' covers contributions on the following topics: CT imaging, PET imaging, fidelity; iterative and few-view CT, CT-analytical; PET/SPECT Compton analytical; doses - spectral methods; phase contrast; compressed sensing- sparse reconstruction; special issues; motion - cardiac.

  6. Computed tomography imaging with the Adaptive Statistical Iterative Reconstruction (ASIR) algorithm: dependence of image quality on the blending level of reconstruction.

    Science.gov (United States)

    Barca, Patrizio; Giannelli, Marco; Fantacci, Maria Evelina; Caramella, Davide

    2018-06-01

    Computed tomography (CT) is a useful and widely employed imaging technique, which represents the largest source of population exposure to ionizing radiation in industrialized countries. Adaptive Statistical Iterative Reconstruction (ASIR) is an iterative reconstruction algorithm with the potential to allow reduction of radiation exposure while preserving diagnostic information. The aim of this phantom study was to assess the performance of ASIR, in terms of a number of image quality indices, when different reconstruction blending levels are employed. CT images of the Catphan-504 phantom were reconstructed using conventional filtered back-projection (FBP) and ASIR with reconstruction blending levels of 20, 40, 60, 80, and 100%. Noise, noise power spectrum (NPS), contrast-to-noise ratio (CNR) and modulation transfer function (MTF) were estimated for different scanning parameters and contrast objects. Noise decreased and CNR increased non-linearly up to 50 and 100%, respectively, with increasing blending level of reconstruction. Also, ASIR has proven to modify the NPS curve shape. The MTF of ASIR reconstructed images depended on tube load/contrast and decreased with increasing blending level of reconstruction. In particular, for low radiation exposure and low contrast acquisitions, ASIR showed lower performance than FBP, in terms of spatial resolution for all blending levels of reconstruction. CT image quality varies substantially with the blending level of reconstruction. ASIR has the potential to reduce noise whilst maintaining diagnostic information in low radiation exposure CT imaging. Given the opposite variation of CNR and spatial resolution with the blending level of reconstruction, it is recommended to use an optimal value of this parameter for each specific clinical application.

  7. 1024 matrix image reconstruction: usefulness in high resolution chest CT

    International Nuclear Information System (INIS)

    Jeong, Sun Young; Chung, Myung Jin; Chong, Se Min; Sung, Yon Mi; Lee, Kyung Soo

    2006-01-01

    We tried to evaluate whether high resolution chest CT with a 1,024 matrix has a significant advantage in image quality compared to a 512 matrix. Each set of 512 and 1024 matrix high resolution chest CT scans with both 0.625 mm and 1.25 mm slice thickness were obtained from 26 patients. Seventy locations that contained twenty-four low density lesions without sharp boundary such as emphysema, and forty-six sharp linear densities such as linear fibrosis were selected; these were randomly displayed on a five mega pixel LCD monitor. All the images were masked for information concerning the matrix size and slice thickness. Two chest radiologists scored the image quality of each ar rowed lesion as follows: (1) undistinguishable, (2) poorly distinguishable, (3) fairly distinguishable, (4) well visible and (5) excellently visible. The scores were compared from the aspects of matrix size, slice thickness and the different observers by using ANOVA tests. The average and standard deviation of image quality were 3.09 (± .92) for the 0.625 mm x 512 matrix, 3.16 (± .84) for the 0.625 mm x 1024 matrix, 2.49 (± 1.02) for the 1.25 mm x 512 matrix, and 2.35 (± 1.02) for the 1.25 mm x 1024 matrix, respectively. The image quality on both matrices of the high resolution chest CT scans with a 0.625 mm slice thickness was significantly better than that on the 1.25 mm slice thickness (ρ < 0.001). However, the image quality on the 1024 matrix high resolution chest CT scans was not significantly different from that on the 512 matrix high resolution chest CT scans (ρ = 0.678). The interobserver variation between the two observers was not significant (ρ = 0.691). We think that 1024 matrix image reconstruction for high resolution chest CT may not be clinical useful

  8. Images from the Mind: BCI image reconstruction based on Rapid Serial Visual Presentations of polygon primitives

    Directory of Open Access Journals (Sweden)

    Luís F Seoane

    2015-04-01

    Full Text Available We provide a proof of concept for an EEG-based reconstruction of a visual image which is on a user's mind. Our approach is based on the Rapid Serial Visual Presentation (RSVP of polygon primitives and Brain-Computer Interface (BCI technology. In an experimental setup, subjects were presented bursts of polygons: some of them contributed to building a target image (because they matched the shape and/or color of the target while some of them did not. The presentation of the contributing polygons triggered attention-related EEG patterns. These Event Related Potentials (ERPs could be determined using BCI classification and could be matched to the stimuli that elicited them. These stimuli (i.e. the ERP-correlated polygons were accumulated in the display until a satisfactory reconstruction of the target image was reached. As more polygons were accumulated, finer visual details were attained resulting in more challenging classification tasks. In our experiments, we observe an average classification accuracy of around 75%. An in-depth investigation suggests that many of the misclassifications were not misinterpretations of the BCI concerning the users' intent, but rather caused by ambiguous polygons that could contribute to reconstruct several different images. When we put our BCI-image reconstruction in perspective with other RSVP BCI paradigms, there is large room for improvement both in speed and accuracy. These results invite us to be optimistic. They open a plethora of possibilities to explore non-invasive BCIs for image reconstruction both in healthy and impaired subjects and, accordingly, suggest interesting recreational and clinical applications.

  9. Brief review of image reconstruction methods for imaging in nuclear medicine

    International Nuclear Information System (INIS)

    Murayama, Hideo

    1999-01-01

    Emission computed tomography (ECT) has as its major emphasis the quantitative determination of the moment to moment changes in the chemistry and flow physiology of injected or inhaled compounds labeled with radioactive atoms in a human body. The major difference lies in the fact that ECT seeks to describe the location and intensity of sources of emitted photons in an attenuating medium whereas transmission X-ray computed tomography (TCT) seeks to determine the distribution of the attenuating medium. A second important difference between ECT and TCT is that of available statistics. ECT statistics are low because each photon without control in emitting direction must be detected and analyzed, not as in TCT. The following sections review the historical development of image reconstruction methods for imaging in nuclear medicine, relevant intrinsic concepts for image reconstruction on ECT, and current status of volume imaging as well as a unique approach on iterative techniques for ECT. (author). 130 refs

  10. First results of genetic algorithm application in ML image reconstruction in emission tomography

    International Nuclear Information System (INIS)

    Smolik, W.

    1999-01-01

    This paper concerns application of genetic algorithm in maximum likelihood image reconstruction in emission tomography. The example of genetic algorithm for image reconstruction is presented. The genetic algorithm was based on the typical genetic scheme modified due to the nature of solved problem. The convergence of algorithm was examined. The different adaption functions, selection and crossover methods were verified. The algorithm was tested on simulated SPECT data. The obtained results of image reconstruction are discussed. (author)

  11. Comparison of clinical and physics scoring of PET images when image reconstruction parameters are varied

    International Nuclear Information System (INIS)

    Walsh, C.; Johnston, C.; Sheehy, N.; Reilly, G. O.

    2013-01-01

    In this study the quantitative and qualitative image quality (IQ) measurements with clinical judgement of IQ in positron emission tomography (PET) were compared. The limitations of IQ metrics and the proposed criteria of acceptability for PET scanners are discussed. Phantom and patient images were reconstructed using seven different iterative reconstruction protocols. For each reconstructed set of images, IQ was scored based both on the visual analysis and on the quantitative metrics. The quantitative physics metrics did not rank the reconstruction protocols in the same order as the clinicians' scoring of perceived IQ (R s = -0.54). Better agreement was achieved when comparing the clinical perception of IQ to the physicist's visual assessment of IQ in the phantom images (R s = +0.59). The closest agreement was seen between the quantitative physics metrics and the measurement of the standard uptake values (SUVs) in small tumours (R s = +0.92). Given the disparity between the clinical perception of IQ and the physics metrics a cautious approach to use of IQ measurements for determining suspension levels is warranted. (authors)

  12. Isotope specific resolution recovery image reconstruction in high resolution PET imaging

    NARCIS (Netherlands)

    Kotasidis, Fotis A.; Angelis, Georgios I.; Anton-Rodriguez, Jose; Matthews, Julian C.; Reader, Andrew J.; Zaidi, Habib

    Purpose: Measuring and incorporating a scanner-specific point spread function (PSF) within image reconstruction has been shown to improve spatial resolution in PET. However, due to the short half-life of clinically used isotopes, other long-lived isotopes not used in clinical practice are used to

  13. Image improvement and three-dimensional reconstruction using holographic image processing

    Science.gov (United States)

    Stroke, G. W.; Halioua, M.; Thon, F.; Willasch, D. H.

    1977-01-01

    Holographic computing principles make possible image improvement and synthesis in many cases of current scientific and engineering interest. Examples are given for the improvement of resolution in electron microscopy and 3-D reconstruction in electron microscopy and X-ray crystallography, following an analysis of optical versus digital computing in such applications.

  14. 2-D Fused Image Reconstruction approach for Microwave Tomography: a theoretical assessment using FDTD Model.

    Science.gov (United States)

    Bindu, G; Semenov, S

    2013-01-01

    This paper describes an efficient two-dimensional fused image reconstruction approach for Microwave Tomography (MWT). Finite Difference Time Domain (FDTD) models were created for a viable MWT experimental system having the transceivers modelled using thin wire approximation with resistive voltage sources. Born Iterative and Distorted Born Iterative methods have been employed for image reconstruction with the extremity imaging being done using a differential imaging technique. The forward solver in the imaging algorithm employs the FDTD method of solving the time domain Maxwell's equations with the regularisation parameter computed using a stochastic approach. The algorithm is tested with 10% noise inclusion and successful image reconstruction has been shown implying its robustness.

  15. Time Reversal Reconstruction Algorithm Based on PSO Optimized SVM Interpolation for Photoacoustic Imaging

    Directory of Open Access Journals (Sweden)

    Mingjian Sun

    2015-01-01

    Full Text Available Photoacoustic imaging is an innovative imaging technique to image biomedical tissues. The time reversal reconstruction algorithm in which a numerical model of the acoustic forward problem is run backwards in time is widely used. In the paper, a time reversal reconstruction algorithm based on particle swarm optimization (PSO optimized support vector machine (SVM interpolation method is proposed for photoacoustics imaging. Numerical results show that the reconstructed images of the proposed algorithm are more accurate than those of the nearest neighbor interpolation, linear interpolation, and cubic convolution interpolation based time reversal algorithm, which can provide higher imaging quality by using significantly fewer measurement positions or scanning times.

  16. MO-C-18A-01: Advances in Model-Based 3D Image Reconstruction

    International Nuclear Information System (INIS)

    Chen, G; Pan, X; Stayman, J; Samei, E

    2014-01-01

    Recent years have seen the emergence of CT image reconstruction techniques that exploit physical models of the imaging system, photon statistics, and even the patient to achieve improved 3D image quality and/or reduction of radiation dose. With numerous advantages in comparison to conventional 3D filtered backprojection, such techniques bring a variety of challenges as well, including: a demanding computational load associated with sophisticated forward models and iterative optimization methods; nonlinearity and nonstationarity in image quality characteristics; a complex dependency on multiple free parameters; and the need to understand how best to incorporate prior information (including patient-specific prior images) within the reconstruction process. The advantages, however, are even greater – for example: improved image quality; reduced dose; robustness to noise and artifacts; task-specific reconstruction protocols; suitability to novel CT imaging platforms and noncircular orbits; and incorporation of known characteristics of the imager and patient that are conventionally discarded. This symposium features experts in 3D image reconstruction, image quality assessment, and the translation of such methods to emerging clinical applications. Dr. Chen will address novel methods for the incorporation of prior information in 3D and 4D CT reconstruction techniques. Dr. Pan will show recent advances in optimization-based reconstruction that enable potential reduction of dose and sampling requirements. Dr. Stayman will describe a “task-based imaging” approach that leverages models of the imaging system and patient in combination with a specification of the imaging task to optimize both the acquisition and reconstruction process. Dr. Samei will describe the development of methods for image quality assessment in such nonlinear reconstruction techniques and the use of these methods to characterize and optimize image quality and dose in a spectrum of clinical

  17. Image reconstruction for a Positron Emission Tomograph optimized for breast cancer imaging

    International Nuclear Information System (INIS)

    Virador, Patrick R.G.

    2000-01-01

    The author performs image reconstruction for a novel Positron Emission Tomography camera that is optimized for breast cancer imaging. This work addresses for the first time, the problem of fully-3D, tomographic reconstruction using a septa-less, stationary, (i.e. no rotation or linear motion), and rectangular camera whose Field of View (FOV) encompasses the entire volume enclosed by detector modules capable of measuring Depth of Interaction (DOI) information. The camera is rectangular in shape in order to accommodate breasts of varying sizes while allowing for soft compression of the breast during the scan. This non-standard geometry of the camera exacerbates two problems: (a) radial elongation due to crystal penetration and (b) reconstructing images from irregularly sampled data. Packing considerations also give rise to regions in projection space that are not sampled which lead to missing information. The author presents new Fourier Methods based image reconstruction algorithms that incorporate DOI information and accommodate the irregular sampling of the camera in a consistent manner by defining lines of responses (LORs) between the measured interaction points instead of rebinning the events into predefined crystal face LORs which is the only other method to handle DOI information proposed thus far. The new procedures maximize the use of the increased sampling provided by the DOI while minimizing interpolation in the data. The new algorithms use fixed-width evenly spaced radial bins in order to take advantage of the speed of the Fast Fourier Transform (FFT), which necessitates the use of irregular angular sampling in order to minimize the number of unnormalizable Zero-Efficiency Bins (ZEBs). In order to address the persisting ZEBs and the issue of missing information originating from packing considerations, the algorithms (a) perform nearest neighbor smoothing in 2D in the radial bins (b) employ a semi-iterative procedure in order to estimate the unsampled data

  18. Image reconstruction for a Positron Emission Tomograph optimized for breast cancer imaging

    Energy Technology Data Exchange (ETDEWEB)

    Virador, Patrick R.G. [Univ. of California, Berkeley, CA (United States)

    2000-04-01

    The author performs image reconstruction for a novel Positron Emission Tomography camera that is optimized for breast cancer imaging. This work addresses for the first time, the problem of fully-3D, tomographic reconstruction using a septa-less, stationary, (i.e. no rotation or linear motion), and rectangular camera whose Field of View (FOV) encompasses the entire volume enclosed by detector modules capable of measuring Depth of Interaction (DOI) information. The camera is rectangular in shape in order to accommodate breasts of varying sizes while allowing for soft compression of the breast during the scan. This non-standard geometry of the camera exacerbates two problems: (a) radial elongation due to crystal penetration and (b) reconstructing images from irregularly sampled data. Packing considerations also give rise to regions in projection space that are not sampled which lead to missing information. The author presents new Fourier Methods based image reconstruction algorithms that incorporate DOI information and accommodate the irregular sampling of the camera in a consistent manner by defining lines of responses (LORs) between the measured interaction points instead of rebinning the events into predefined crystal face LORs which is the only other method to handle DOI information proposed thus far. The new procedures maximize the use of the increased sampling provided by the DOI while minimizing interpolation in the data. The new algorithms use fixed-width evenly spaced radial bins in order to take advantage of the speed of the Fast Fourier Transform (FFT), which necessitates the use of irregular angular sampling in order to minimize the number of unnormalizable Zero-Efficiency Bins (ZEBs). In order to address the persisting ZEBs and the issue of missing information originating from packing considerations, the algorithms (a) perform nearest neighbor smoothing in 2D in the radial bins (b) employ a semi-iterative procedure in order to estimate the unsampled data

  19. Separated reconstruction of images from ultrasonic holograms with tridimensional object by digital processing

    International Nuclear Information System (INIS)

    Son, J.H.

    1979-01-01

    Because of much attractiveness, digital reconstruction of image from ultrasonic hologram by computer has been widely studied in recent years. But the method of digital reconstruction of image is displayed in the plain only, so study is done mainly of the hologram obtained from bidimensional objects. Many applications of the ultrasonic holography such as the non-distructive testing and the ultrasonic diagnosis are mostly of the tridimensional object. In the ordinary digital reconstruction of the image from the hologram obtained from tridimensional object, a question of hidden-image problem arises, and the separated reconstruction of the image for the considered part of the object is required. In this paper, multi-diffraction by tridimensional object is assumed to have linearity, ie. superposition property by each diffraction of bidimensional objects. And a new algorithm is proposed here, namely reconstructed image for considered one of bidimensional objects in tridimensional object obtained by means of operation from the two holograms tilted in unequal angles. Such tilted holograms are obtained from the tilted linear array receivers by scanning method. That images can be reconstructed by the operation from two holograms means that the new algorithm is verified. And another new method of the transformation of hologram, that is, transformation of a hologram to arbitrarily tilted hologram, has been proved valid. The reconstructed images obtained with the method of transformation and the method of operation, are the images reconstructed from one hologram by the tridimensional object and more distinctly separated that any images mentioned above. (author)

  20. Current profile reconstruction using electron temperature imaging diagnostics

    International Nuclear Information System (INIS)

    Tritz, K.; Stutman, D.; Delgado-Aparicio, L.F.; Finkenthal, M.; Pacella, D.; Kaita, R.; Stratton, B.; Sabbagh, S.

    2004-01-01

    Flux surface shape information can be used to constrain the current profile for reconstruction of the plasma equilibrium. One method of inferring flux surface shape relies on plasma x-ray emission; however, deviations from the flux surfaces due to impurity and density asymmetries complicate the interpretation. Electron isotherm surfaces should correspond well to the plasma flux surfaces, and equilibrium constraint modeling using this isotherm information constrains the current profile. The KFIT code is used to assess the profile uncertainty and to optimize the number, location and SNR required for the Te detectors. As Te imaging detectors we consider tangentially viewing, vertically spaced, linear gas electron multiplier arrays operated in pulse height analysis (PHA) mode and multifoil soft x-ray arrays. Isoflux coordinate sets provided by T e measurements offer a strong constraint on the equilibrium reconstruction in both a stacked horizontal array configuration and a crossed horizontal and vertical beam system, with q 0 determined to within ±4%. The required SNR can be provided with either PHA or multicolor diagnostic techniques, though the multicolor system requires ∼x4 better statistics for comparable final errors

  1. Image reconstruction in k-space from MR data encoded with ambiguous gradient fields.

    Science.gov (United States)

    Schultz, Gerrit; Gallichan, Daniel; Weber, Hans; Witschey, Walter R T; Honal, Matthias; Hennig, Jürgen; Zaitsev, Maxim

    2015-02-01

    In this work, the limits of image reconstruction in k-space are explored when non-bijective gradient fields are used for spatial encoding. The image space analogy between parallel imaging and imaging with non-bijective encoding fields is partially broken in k-space. As a consequence, it is hypothesized and proven that ambiguities can only be resolved partially in k-space, and not completely as is the case in image space. Image-space and k-space based reconstruction algorithms for multi-channel radiofrequency data acquisitions are programmed and tested using numerical simulations as well as in vivo measurement data. The hypothesis is verified based on an analysis of reconstructed images. It is found that non-bijective gradient fields have the effect that densely sampled autocalibration data, used for k-space reconstruction, provide less information than a separate scan of the receiver coil sensitivity maps, used for image space reconstruction. Consequently, in k-space only the undersampling artifact can be unfolded, whereas in image space, it is also possible to resolve aliasing that is caused by the non-bijectivity of the gradient fields. For standard imaging, reconstruction in image space and in k-space is nearly equivalent, whereas there is a fundamental difference with practical consequences for the selection of image reconstruction algorithms when non-bijective encoding fields are involved. © 2014 Wiley Periodicals, Inc.

  2. Focal dynamics of multiple filaments: Microscopic imaging and reconstruction

    International Nuclear Information System (INIS)

    Kiran, P. Prem; Bagchi, Suman; Kumar, G. Ravindra; Krishnan, Siva Rama; Arnold, C. L.; Couairon, A.

    2010-01-01

    We observe the complete dynamics of the propagation of very intense, femtosecond laser pulses in air under tight focusing conditions via direct imaging of the entire interaction zone. The whole life history of the focused pulses is then reconstructed by means of numerical simulations. We show that beam breakup leads to a dual-rate increase in filament numbers with laser power. Linearly and circularly polarized pulses give rise to beam breakup and fusion governed by external focusing conditions. For tight focusing conditions, intensity saturation due to plasma generation and nonlinear losses does not limit the intensity growth, thereby giving access to a new propagation regime featured by an efficient laser energy deposition in fully ionized air and intense 10 15 W/cm 2 pulses at the focus.

  3. Magnetic resonance imaging evaluation of cruciate ligaments after arthroscopic reconstruction

    Directory of Open Access Journals (Sweden)

    Amit Kharat

    2017-01-01

    Full Text Available Background: Due to increase in road traffic and sports injuries, tears of anterior cruciate ligament (ACL and the posterior cruciate ligament (PCL of the knee are common. Magnetic resonance imaging (MRI is emerging as an important tool of diagnosis and evaluation of these injuries. Methods: We carried out a prospective study on role of MRI on ten patients who had undergone ACL or PCL repair over a period of six months. In this report we present three illustrative cases to capture the spectrum of findings in our series to underline the role of MRI in management of such injuries and discuss the modalities of the procedure. Results: In our series, as demonstrated by the cases, MRI had an important role in diagnosis and evaluation of injuries to the cruciate ligaments. Conclusion: MRI can play an important role, particularly in tertiary centres, in diagnosis and evaluation of reconstructed ACL and PCL ligaments of the knee joint.

  4. Algorithms of CT value correction for reconstructing a radiotherapy simulation image through axial CT images

    International Nuclear Information System (INIS)

    Ogino, Takashi; Egawa, Sunao

    1991-01-01

    New algorithms of CT value correction for reconstructing a radiotherapy simulation image through axial CT images were developed. One, designated plane weighting method, is to correct CT value in proportion to the position of the beam element passing through the voxel. The other, designated solid weighting method, is to correct CT value in proportion to the length of the beam element passing through the voxel and the volume of voxel. Phantom experiments showed fair spatial resolution in the transverse direction. In the longitudinal direction, however, spatial resolution of under slice thickness could not be obtained. Contrast resolution was equivalent for both methods. In patient studies, the reconstructed radiotherapy simulation image was almost similar in visual perception of the density resolution to a simulation film taken by X-ray simulator. (author)

  5. Consistent reconstruction of 4D fetal heart ultrasound images to cope with fetal motion.

    Science.gov (United States)

    Tanner, Christine; Flach, Barbara; Eggenberger, Céline; Mattausch, Oliver; Bajka, Michael; Goksel, Orcun

    2017-08-01

    4D ultrasound imaging of the fetal heart relies on reconstructions from B-mode images. In the presence of fetal motion, current approaches suffer from artifacts, which are unrecoverable for single sweeps. We propose to use many sweeps and exploit the resulting redundancy to automatically recover from motion by reconstructing a 4D image which is consistent in phase, space, and time. An interactive visualization framework to view animated ultrasound slices from 4D reconstructions on arbitrary planes was developed using a magnetically tracked mock probe. We first quantified the performance of 10 4D reconstruction formulations on simulated data. Reconstructions of 14 in vivo sequences by a baseline, the current state-of-the-art, and the proposed approach were then visually ranked with respect to temporal quality on orthogonal views. Rankings from 5 observers showed that the proposed 4D reconstruction approach significantly improves temporal image quality in comparison with the baseline. The 4D reconstructions of the baseline and the proposed methods were then inspected interactively for accessibility to clinically important views and rated for their clinical usefulness by an ultrasound specialist in obstetrics and gynecology. The reconstructions by the proposed method were rated as 'very useful' in 71% and were statistically significantly more useful than the baseline reconstructions. Multi-sweep fetal heart ultrasound acquisitions in combination with consistent 4D image reconstruction improves quality as well as clinical usefulness of the resulting 4D images in the presence of fetal motion.

  6. Cone-beam and fan-beam image reconstruction algorithms based on spherical and circular harmonics

    International Nuclear Information System (INIS)

    Zeng, Gengsheng L; Gullberg, Grant T

    2004-01-01

    A cone-beam image reconstruction algorithm using spherical harmonic expansions is proposed. The reconstruction algorithm is in the form of a summation of inner products of two discrete arrays of spherical harmonic expansion coefficients at each cone-beam point of acquisition. This form is different from the common filtered backprojection algorithm and the direct Fourier reconstruction algorithm. There is no re-sampling of the data, and spherical harmonic expansions are used instead of Fourier expansions. As a special case, a new fan-beam image reconstruction algorithm is also derived in terms of a circular harmonic expansion. Computer simulation results for both cone-beam and fan-beam algorithms are presented for circular planar orbit acquisitions. The algorithms give accurate reconstructions; however, the implementation of the cone-beam reconstruction algorithm is computationally intensive. A relatively efficient algorithm is proposed for reconstructing the central slice of the image when a circular scanning orbit is used

  7. Image quality of iterative reconstruction in cranial CT imaging: comparison of model-based iterative reconstruction (MBIR) and adaptive statistical iterative reconstruction (ASiR)

    Energy Technology Data Exchange (ETDEWEB)

    Notohamiprodjo, S.; Deak, Z.; Meurer, F.; Maertz, F.; Mueck, F.G.; Geyer, L.L.; Wirth, S. [Ludwig-Maximilians University Hospital of Munich, Institute for Clinical Radiology, Munich (Germany)

    2015-01-15

    The purpose of this study was to compare cranial CT (CCT) image quality (IQ) of the MBIR algorithm with standard iterative reconstruction (ASiR). In this institutional review board (IRB)-approved study, raw data sets of 100 unenhanced CCT examinations (120 kV, 50-260 mAs, 20 mm collimation, 0.984 pitch) were reconstructed with both ASiR and MBIR. Signal-to-noise (SNR) and contrast-to-noise (CNR) were calculated from attenuation values measured in caudate nucleus, frontal white matter, anterior ventricle horn, fourth ventricle, and pons. Two radiologists, who were blinded to the reconstruction algorithms, evaluated anonymized multiplanar reformations of 2.5 mm with respect to depiction of different parenchymal structures and impact of artefacts on IQ with a five-point scale (0: unacceptable, 1: less than average, 2: average, 3: above average, 4: excellent). MBIR decreased artefacts more effectively than ASiR (p < 0.01). The median depiction score for MBIR was 3, whereas the median value for ASiR was 2 (p < 0.01). SNR and CNR were significantly higher in MBIR than ASiR (p < 0.01). MBIR showed significant improvement of IQ parameters compared to ASiR. As CCT is an examination that is frequently required, the use of MBIR may allow for substantial reduction of radiation exposure caused by medical diagnostics. (orig.)

  8. Image quality of iterative reconstruction in cranial CT imaging: comparison of model-based iterative reconstruction (MBIR) and adaptive statistical iterative reconstruction (ASiR)

    International Nuclear Information System (INIS)

    Notohamiprodjo, S.; Deak, Z.; Meurer, F.; Maertz, F.; Mueck, F.G.; Geyer, L.L.; Wirth, S.

    2015-01-01

    The purpose of this study was to compare cranial CT (CCT) image quality (IQ) of the MBIR algorithm with standard iterative reconstruction (ASiR). In this institutional review board (IRB)-approved study, raw data sets of 100 unenhanced CCT examinations (120 kV, 50-260 mAs, 20 mm collimation, 0.984 pitch) were reconstructed with both ASiR and MBIR. Signal-to-noise (SNR) and contrast-to-noise (CNR) were calculated from attenuation values measured in caudate nucleus, frontal white matter, anterior ventricle horn, fourth ventricle, and pons. Two radiologists, who were blinded to the reconstruction algorithms, evaluated anonymized multiplanar reformations of 2.5 mm with respect to depiction of different parenchymal structures and impact of artefacts on IQ with a five-point scale (0: unacceptable, 1: less than average, 2: average, 3: above average, 4: excellent). MBIR decreased artefacts more effectively than ASiR (p < 0.01). The median depiction score for MBIR was 3, whereas the median value for ASiR was 2 (p < 0.01). SNR and CNR were significantly higher in MBIR than ASiR (p < 0.01). MBIR showed significant improvement of IQ parameters compared to ASiR. As CCT is an examination that is frequently required, the use of MBIR may allow for substantial reduction of radiation exposure caused by medical diagnostics. (orig.)

  9. Reconstructed coronal views of CT and isotopic images of the pancreas

    International Nuclear Information System (INIS)

    Kasuga, Toshio; Kobayashi, Toshio; Nakanishi, Fumiko

    1980-01-01

    To compare functional images of the pancreas by scintigraphy with morphological views of the pancreas by CT, CT coronal views of the pancreas were reconstructed. As CT coronal views were reconstructed from the routine scanning, there was a problem in longitudinal spatial resolution. However, almost satisfactory total images of the pancreas were obtained by improving images adequately. In 27 patients whose diseases had been confirmed, it was easy to compare pancreatic scintigrams with pancreatic CT images by using reconstructed CT coronal views, and information which had not been obtained by original CT images could be obtained by using reconstructed CT coronal views. Especially, defects on pancreatic images and the shape of pancreas which had not been visualized clearly by scintigraphy alone could be visualized by using reconstructed CT coronal views of the pancreas. (Tsunoda, M.)

  10. Molecular Imaging : Computer Reconstruction and Practice - Proceedings of the NATO Advanced Study Institute on Molecular Imaging from Physical Principles to Computer Reconstruction and Practice

    CERN Document Server

    Lemoigne, Yves

    2008-01-01

    This volume collects the lectures presented at the ninth ESI School held at Archamps (FR) in November 2006 and is dedicated to nuclear physics applications in molecular imaging. The lectures focus on the multiple facets of image reconstruction processing and management and illustrate the role of digital imaging in clinical practice. Medical computing and image reconstruction are introduced by analysing the underlying physics principles and their implementation, relevant quality aspects, clinical performance and recent advancements in the field. Several stages of the imaging process are specifically addressed, e.g. optimisation of data acquisition and storage, distributed computing, physiology and detector modelling, computer algorithms for image reconstruction and measurement in tomography applications, for both clinical and biomedical research applications. All topics are presented with didactical language and style, making this book an appropriate reference for students and professionals seeking a comprehen...

  11. Cardiovascular CT angiography in neonates and children : Image quality and potential for radiation dose reduction with iterative image reconstruction techniques

    NARCIS (Netherlands)

    Tricarico, Francesco; Hlavacek, Anthony M.; Schoepf, U. Joseph; Ebersberger, Ullrich; Nance, John W.; Vliegenthart, Rozemarijn; Cho, Young Jun; Spears, J. Reid; Secchi, Francesco; Savino, Giancarlo; Marano, Riccardo; Schoenberg, Stefan O.; Bonomo, Lorenzo; Apfaltrer, Paul

    To evaluate image quality (IQ) of low-radiation-dose paediatric cardiovascular CT angiography (CTA), comparing iterative reconstruction in image space (IRIS) and sinogram-affirmed iterative reconstruction (SAFIRE) with filtered back-projection (FBP) and estimate the potential for further dose

  12. Postoperative evaluation after anterior cruciate ligament reconstruction: Measurements and abnormalities on radiographic and CT imaging

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Min Cheol; Choi, Yun Sun; KIm, Hyoung Seop; Choi, Nam Hong [Nowon Eulji Medical Center, Eulji University, Seoul (Korea, Republic of)

    2016-11-15

    Reconstruction of a ruptured anterior cruciate ligament (ACL) is a well-established procedure for repair of ACL injury. Despite improvement of surgical and rehabilitation techniques over the past decades, up to 25% of patients still fail to regain satisfactory function after an ACL reconstruction. With development of CT imaging techniques for reducing metal artifacts, multi-planar reconstruction, and three-dimensional reconstruction, early post-operative imaging is increasingly being used to provide immediate feedback to surgeons regarding tunnel positioning, fixation, and device placement. Early post-operative radiography and CT imaging are easy to perform and serve as the baseline examinations for future reference.

  13. Reconstructions with identical filling (RIF) of the heart: a physiological approach to image reconstruction in coronary CT angiography

    International Nuclear Information System (INIS)

    Reinartz, S.D.; Diefenbach, B.S.; Kuhl, C.K.; Mahnken, A.H.; Allmendinger, T.

    2012-01-01

    To compare image quality in coronary artery computed tomography angiography (cCTA) using reconstructions with automated phase detection and Reconstructions computed with Identical Filling of the heart (RIF). Seventy-four patients underwent ECG-gated dual source CT (DSCT) between November 2009 and July 2010 for suspected coronary heart disease (n = 35), planning of transcatheter aortic valve replacement (n = 34) or evaluation of ventricular function (n = 5). Image data sets by the RIF formula and automated phase detection were computed and evaluated with the AHA 15-segment model and a 5-grade Likert scale (1: poor, 5: excellent quality). Subgroups regarding rhythm (sinus rhythm = SR; arrhythmia = ARR) and potential premedication were evaluated by a per-segment, per-vessel and per-patient analysis. RIF significantly improved image quality in 10 of 15 coronary segments (P < 0.05). More diagnostic segments were provided by RIF regarding the entire cohort (n = 693 vs. 590, P < 0.001) and all of the subgroups (e.g. ARR: n = 143 vs. 72, P < 0.001). In arrhythmic patients (n = 19), more diagnostic vessels (e.g. LAD: n = 10 vs. 3; P < 0.014) and complete data sets (n = 7 vs. 1; P < 0.001) were produced. RIF reconstruction is superior to automatic diastolic non-edited reconstructions, especially in arrhythmic patients. RIF theory provides a physiological approach for determining the optimal image reconstruction point in ECG-gated CT angiography. (orig.)

  14. Reduction in camera-specific variability in [{sup 123}I]FP-CIT SPECT outcome measures by image reconstruction optimized for multisite settings: impact on age-dependence of the specific binding ratio in the ENC-DAT database of healthy controls

    Energy Technology Data Exchange (ETDEWEB)

    Buchert, Ralph; Lange, Catharina [Charite - Universitaetsmedizin Berlin, Department of Nuclear Medicine, Berlin (Germany); Kluge, Andreas; Bronzel, Marcus [ABX-CRO advanced pharmaceutical services Forschungsgesellschaft m.b.H., Dresden (Germany); Tossici-Bolt, Livia [University Hospital Southampton NHS Foundation Trust, Department of Medical Physics, Southampton (United Kingdom); Dickson, John [University College London Hospital NHS Foundation Trust, Institute of Nuclear Medicine, London (United Kingdom); Asenbaum, Susanne [Medical University of Vienna, Department of Nuclear Medicine, Vienna (Austria); Booij, Jan [University of Amsterdam, Department of Nuclear Medicine, Academic Medical Centre, Amsterdam (Netherlands); Kapucu, L. Oezlem Atay [Gazi University, Department of Nuclear Medicine, Faculty of Medicine, Ankara (Turkey); Svarer, Claus [Rigshospitalet and University of Copenhagen, Neurobiology Research Unit, Copenhagen (Denmark); Koulibaly, Pierre-Malick [University of Nice-Sophia Antipolis, Nuclear Medicine Department, Centre Antoine Lacassagne, Nice (France); Nobili, Flavio [University of Genoa, Department of Neuroscience (DINOGMI), Clinical Neurology Unit, Genoa (Italy); Pagani, Marco [CNR, Institute of Cognitive Sciences and Technologies, Rome (Italy); Karolinska Hospital, Department of Nuclear Medicine, Stockholm (Sweden); Sabri, Osama [University of Leipzig, Department of Nuclear Medicine, Leipzig (Germany); Sera, Terez [University of Szeged, Department of Nuclear Medicine and Euromedic Szeged, Szeged (Hungary); Tatsch, Klaus [Municipal Hospital of Karlsruhe Inc, Department of Nuclear Medicine, Karlsruhe (Germany); Borght, Thierry vander [CHU Namur, IREC, Nuclear Medicine Division, Universite catholique de Louvain, Yvoir (Belgium); Laere, Koen van [University Hospital and K.U. Leuven, Nuclear Medicine, Leuven (Belgium); Varrone, Andrea [Karolinska University Hospital, Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm (Sweden); Iida, Hidehiro [National Cerebral and Cardiovascular Center - Research Institute, Osaka (Japan)

    2016-07-15

    Quantitative estimates of dopamine transporter availability, determined with [{sup 123}I]FP-CIT SPECT, depend on the SPECT equipment, including both hardware and (reconstruction) software, which limits their use in multicentre research and clinical routine. This study tested a dedicated reconstruction algorithm for its ability to reduce camera-specific intersubject variability in [{sup 123}I]FP-CIT SPECT. The secondary aim was to evaluate binding in whole brain (excluding striatum) as a reference for quantitative analysis. Of 73 healthy subjects from the European Normal Control Database of [{sup 123}I]FP-CIT recruited at six centres, 70 aged between 20 and 82 years were included. SPECT images were reconstructed using the QSPECT software package which provides fully automated detection of the outer contour of the head, camera-specific correction for scatter and septal penetration by transmission-dependent convolution subtraction, iterative OSEM reconstruction including attenuation correction, and camera-specific ''to kBq/ml'' calibration. LINK and HERMES reconstruction were used for head-to-head comparison. The specific striatal [{sup 123}I]FP-CIT binding ratio (SBR) was computed using the Southampton method with binding in the whole brain, occipital cortex or cerebellum as the reference. The correlation between SBR and age was used as the primary quality measure. The fraction of SBR variability explained by age was highest (1) with QSPECT, independently of the reference region, and (2) with whole brain as the reference, independently of the reconstruction algorithm. QSPECT reconstruction appears to be useful for reduction of camera-specific intersubject variability of [{sup 123}I]FP-CIT SPECT in multisite and single-site multicamera settings. Whole brain excluding striatal binding as the reference provides more stable quantitative estimates than occipital or cerebellar binding. (orig.)

  15. Does thorax EIT image analysis depend on the image reconstruction method?

    Science.gov (United States)

    Zhao, Zhanqi; Frerichs, Inéz; Pulletz, Sven; Müller-Lisse, Ullrich; Möller, Knut

    2013-04-01

    Different methods were proposed to analyze the resulting images of electrical impedance tomography (EIT) measurements during ventilation. The aim of our study was to examine if the analysis methods based on back-projection deliver the same results when applied on images based on other reconstruction algorithms. Seven mechanically ventilated patients with ARDS were examined by EIT. The thorax contours were determined from the routine CT images. EIT raw data was reconstructed offline with (1) filtered back-projection with circular forward model (BPC); (2) GREIT reconstruction method with circular forward model (GREITC) and (3) GREIT with individual thorax geometry (GREITT). Three parameters were calculated on the resulting images: linearity, global ventilation distribution and regional ventilation distribution. The results of linearity test are 5.03±2.45, 4.66±2.25 and 5.32±2.30 for BPC, GREITC and GREITT, respectively (median ±interquartile range). The differences among the three methods are not significant (p = 0.93, Kruskal-Wallis test). The proportions of ventilation in the right lung are 0.58±0.17, 0.59±0.20 and 0.59±0.25 for BPC, GREITC and GREITT, respectively (p = 0.98). The differences of the GI index based on different reconstruction methods (0.53±0.16, 0.51±0.25 and 0.54±0.16 for BPC, GREITC and GREITT, respectively) are also not significant (p = 0.93). We conclude that the parameters developed for images generated with GREITT are comparable with filtered back-projection and GREITC.

  16. A Method for Interactive 3D Reconstruction of Piecewise Planar Objects from Single Images

    OpenAIRE

    Sturm , Peter; Maybank , Steve

    1999-01-01

    International audience; We present an approach for 3D reconstruction of objects from a single image. Obviously, constraints on the 3D structure are needed to perform this task. Our approach is based on user-provided coplanarity, perpendicularity and parallelism constraints. These are used to calibrate the image and perform 3D reconstruction. The method is described in detail and results are provided.

  17. Influence of light refraction on the image reconstruction in transmission optical tomography of scattering media

    International Nuclear Information System (INIS)

    Tereshchenko, Sergei A; Potapov, D A; Podgaetskii, Vitalii M; Smirnov, A V

    2002-01-01

    A distorting influence of light refraction at the boundaries of scattering media on the results of tomographic reconstruction of images of radially symmetric objects is investigated. The methods for the correction of such refraction-caused distortions are described. The results of the image reconstruction for two model cylindrical objects are presented.

  18. Influence of iterative image reconstruction on CT-based calcium score measurements

    NARCIS (Netherlands)

    van Osch, Jochen A. C.; Mouden, Mohamed; van Dalen, Jorn A.; Timmer, Jorik R.; Reiffers, Stoffer; Knollema, Siert; Greuter, Marcel J. W.; Ottervanger, Jan Paul; Jager, Piet L.

    Iterative reconstruction techniques for coronary CT angiography have been introduced as an alternative for traditional filter back projection (FBP) to reduce image noise, allowing improved image quality and a potential for dose reduction. However, the impact of iterative reconstruction on the

  19. Improvement of image quality and dose management in CT fluoroscopy by iterative 3D image reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Grosser, Oliver S.; Kupitz, Dennis; Powerski, Maciej; Mohnike, Konrad; Ricke, Jens [University Hospital Magdeburg, Department of Radiology and Nuclear Medicine, Magdeburg (Germany); Wybranski, Christian [University Hospital Magdeburg, Department of Radiology and Nuclear Medicine, Magdeburg (Germany); University Hospital Cologne, Institute for Diagnostic and Interventional Radiology, Cologne (Germany); Pech, Maciej [University Hospital Magdeburg, Department of Radiology and Nuclear Medicine, Magdeburg (Germany); Medical University of Gdansk, Second Department of Radiology, Gdansk (Poland); Amthauer, Holger [University Hospital Magdeburg, Department of Radiology and Nuclear Medicine, Magdeburg (Germany); Charite, Department of Nuclear Medicine, Berlin (Germany)

    2017-09-15

    The objective of this study was to assess the influence of an iterative CT reconstruction algorithm (IA), newly available for CT-fluoroscopy (CTF), on image noise, readers' confidence and effective dose compared to filtered back projection (FBP). Data from 165 patients (FBP/IA = 82/74) with CTF in the thorax, abdomen and pelvis were included. Noise was analysed in a large-diameter vessel. The impact of reconstruction and variables (e.g. X-ray tube current I) influencing noise and effective dose were analysed by ANOVA and a pairwise t-test with Bonferroni-Holm correction. Noise and readers' confidence were evaluated by three readers. Noise was significantly influenced by reconstruction, I, body region and circumference (all p ≤ 0.0002). IA reduced the noise significantly compared to FBP (p = 0.02). The effect varied for body regions and circumferences (p ≤ 0.001). The effective dose was influenced by the reconstruction, body region, interventional procedure and I (all p ≤ 0.02). The inter-rater reliability for noise and readers' confidence was good (W ≥ 0.75, p < 0.0001). Noise and readers' confidence were significantly better in AIDR-3D compared to FBP (p ≤ 0.03). Generally, IA yielded a significant reduction of the median effective dose. The CTF reconstruction by IA showed a significant reduction in noise and effective dose while readers' confidence increased. (orig.)

  20. Experimental validation of incomplete data CT image reconstruction techniques

    International Nuclear Information System (INIS)

    Eberhard, J.W.; Hsiao, M.L.; Tam, K.C.

    1989-01-01

    X-ray CT inspection of large metal parts is often limited by x-ray penetration problems along many of the ray paths required for a complete CT data set. In addition, because of the complex geometry of many industrial parts, manipulation difficulties often prevent scanning over some range of angles. CT images reconstructed from these incomplete data sets contain a variety of artifacts which limit their usefulness in part quality determination. Over the past several years, the authors' company has developed 2 new methods of incorporating a priori information about the parts under inspection to significantly improve incomplete data CT image quality. This work reviews the methods which were developed and presents experimental results which confirm the effectiveness of the techniques. The new methods for dealing with incomplete CT data sets rely on a priori information from part blueprints (in electronic form), outer boundary information from touch sensors, estimates of part outer boundaries from available x-ray data, and linear x-ray attenuation coefficients of the part. The two methods make use of this information in different fashions. The relative performance of the two methods in detecting various flaw types is compared. Methods for accurately registering a priori information with x-ray data are also described. These results are critical to a new industrial x-ray inspection cell built for inspection of large aircraft engine parts

  1. Influence of attenuation correction and reconstruction techniques on the detection of hypoperfused lesions in brain SPECT studies

    International Nuclear Information System (INIS)

    Ghoorun, S.; Groenewald, W.A.; Baete, K.; Nuyts, J.; Dupont, P.

    2004-01-01

    Full text: Aim: To study the influence of attenuation correction and the reconstruction technique on the detection of hypoperfused lesions in brain SPECT imaging, Material and Methods: A simulation experiment was used in which the effects of attenuation and reconstruction were decoupled, A high resolution SPECT phantom was constructed using the BrainWeb database, In this phantom, activity values were assigned to grey and white matter (ratio 4:1) and scaled to obtain counts of the same magnitude as in clinical practice, The true attenuation map was generated by assigning attenuation coefficients to each tissue class (grey and white matter, cerebral spinal fluid, skull, soft and fatty tissue and air) to create a non-uniform attenuation map, The uniform attenuation map was calculated using an attenuation coefficient of 0.15 cm-1, Hypoperfused lesions of varying intensities and sizes were added. The phantom was then projected as typical SPECT projection data, taking into account attenuation and collimator blurring with the addition of Poisson noise, The projection data was reconstructed using four different methods of reconstruction: (1) filtered backprojection (FBP) with the uniform attenuation map; (2) FBP using the true attenuation map; (3) ordered subset expectation maximization (OSEM) (equivalent to 423 iterations) with a uniform attenuation map; and (4) OSEM with a true attenuation map. Different Gaussian postsmooth kernels were applied to the reconstructed images. Results: The analysis of the reconstructed data was performed using figures of merit such as signal to noise ratio (SNR), bias and variance. The results illustrated that uniform attenuation correction offered slight deterioration (less than 2%) with regard to SNR when compared to the ideal attenuation map. which in reality is not known. The iterative techniques produced superior signal to noise ratios (increase of 5 - 20 % depending on the lesion and the postsmooth) in comparison to the FBP methods

  2. Comparison of different reconstruction algorithms for three-dimensional ultrasound imaging in a neurosurgical setting.

    Science.gov (United States)

    Miller, D; Lippert, C; Vollmer, F; Bozinov, O; Benes, L; Schulte, D M; Sure, U

    2012-09-01

    Freehand three-dimensional ultrasound imaging (3D-US) is increasingly used in image-guided surgery. During image acquisition, a set of B-scans is acquired that is distributed in a non-parallel manner over the area of interest. Reconstructing these images into a regular array allows 3D visualization. However, the reconstruction process may introduce artefacts and may therefore reduce image quality. The aim of the study is to compare different algorithms with respect to image quality and diagnostic value for image guidance in neurosurgery. 3D-US data sets were acquired during surgery of various intracerebral lesions using an integrated ultrasound-navigation device. They were stored for post-hoc evaluation. Five different reconstruction algorithms, a standard multiplanar reconstruction with interpolation (MPR), a pixel nearest neighbour method (PNN), a voxel nearest neighbour method (VNN) and two voxel based distance-weighted algorithms (VNN2 and DW) were tested with respect to image quality and artefact formation. The capability of the algorithm to fill gaps within the sample volume was investigated and a clinical evaluation with respect to the diagnostic value of the reconstructed images was performed. MPR was significantly worse than the other algorithms in filling gaps. In an image subtraction test, VNN2 and DW reliably reconstructed images even if large amounts of data were missing. However, the quality of the reconstruction improved, if data acquisition was performed in a structured manner. When evaluating the diagnostic value of reconstructed axial, sagittal and coronal views, VNN2 and DW were judged to be significantly better than MPR and VNN. VNN2 and DW could be identified as robust algorithms that generate reconstructed US images with a high diagnostic value. These algorithms improve the utility and reliability of 3D-US imaging during intraoperative navigation. Copyright © 2012 John Wiley & Sons, Ltd.

  3. Super resolution reconstruction of infrared images based on classified dictionary learning

    Science.gov (United States)

    Liu, Fei; Han, Pingli; Wang, Yi; Li, Xuan; Bai, Lu; Shao, Xiaopeng

    2018-05-01

    Infrared images always suffer from low-resolution problems resulting from limitations of imaging devices. An economical approach to combat this problem involves reconstructing high-resolution images by reasonable methods without updating devices. Inspired by compressed sensing theory, this study presents and demonstrates a Classified Dictionary Learning method to reconstruct high-resolution infrared images. It classifies features of the samples into several reasonable clusters and trained a dictionary pair for each cluster. The optimal pair of dictionaries is chosen for each image reconstruction and therefore, more satisfactory results is achieved without the increase in computational complexity and time cost. Experiments and results demonstrated that it is a viable method for infrared images reconstruction since it improves image resolution and recovers detailed information of targets.

  4. A resolution-enhancing image reconstruction method for few-view differential phase-contrast tomography

    Science.gov (United States)

    Guan, Huifeng; Anastasio, Mark A.

    2017-03-01

    It is well-known that properly designed image reconstruction methods can facilitate reductions in imaging doses and data-acquisition times in tomographic imaging. The ability to do so is particularly important for emerging modalities such as differential X-ray phase-contrast tomography (D-XPCT), which are currently limited by these factors. An important application of D-XPCT is high-resolution imaging of biomedical samples. However, reconstructing high-resolution images from few-view tomographic measurements remains a challenging task. In this work, a two-step sub-space reconstruction strategy is proposed and investigated for use in few-view D-XPCT image reconstruction. It is demonstrated that the resulting iterative algorithm can mitigate the high-frequency information loss caused by data incompleteness and produce images that have better preserved high spatial frequency content than those produced by use of a conventional penalized least squares (PLS) estimator.

  5. Aliasless fresnel transform image reconstruction in phase scrambling fourier transform technique by data interpolation

    International Nuclear Information System (INIS)

    Yamada, Yoshifumi; Liu, Na; Ito, Satoshi

    2006-01-01

    The signal in the Fresnel transform technique corresponds to a blurred one of the spin density image. Because the amplitudes of adjacent sampled signals have a high interrelation, the signal amplitude at a point between sampled points can be estimated with a high degree of accuracy even if the sampling is so coarse as to generate aliasing in the reconstructed images. In this report, we describe a new aliasless image reconstruction technique in the phase scrambling Fourier transform (PSFT) imaging technique in which the PSFT signals are converted to Fresnel transform signals by multiplying them by a quadratic phase term and are then interpolated using polynomial expressions to generate fully encoded signals. Numerical simulation using MR images showed that almost completely aliasless images are reconstructed by this technique. Experiments using ultra-low-field PSFT MRI were conducted, and aliasless images were reconstructed from coarsely sampled PSFT signals. (author)

  6. Image-guided stereotactic surgery using ultrasonography and reconstructive three-dimensional CT-imaging system

    International Nuclear Information System (INIS)

    Kawamura, Hirotsune; Iseki, Hiroshi; Umezawa, Yoshihiro

    1991-01-01

    A new simulation and navigation system utilizing three-dimensional CT images has been developed for image-guided stereotactic surgery. Preoperative CT images are not always useful in predicting the intraoperative location of lesions, for cerebral lesions are easily displaced or distorted by gravity, brain retraction, and/or CSF aspiration during operative procedure. This new system, however, has the advantage that the intraoperative locations of intracranial lesions or the anatomical structures of the brain can be precisely confirmed during stereotactic surgery. Serial CT images were obtained from a patient whose head had been fixed to the ISEKI CT-guided stereotactic frame. The data of serial CT images were saved on a floppy disc and then transferred to the work station (IRIS) using the off line. In order to find the best approach angle for ultrasound-guided stereotactic surgery, three-dimenstional CT images were reconstructed using the work station. The site of the craniotomy or the angle of the trajectory of the ultrasound probe was measured preoperatively based on the three-dimensional CT images. Then, in the operating room, the patient's head was fixed to the ISEKI frame with the subframe at the same position as before according to the measurement of the CT images. In a case of cystic glioma, the predicable ultrasonograms from three-dimensional reconstructive CT images were ascertained to correspond well to the actual ultrasound images during ultrasound-guided stereotactic surgery. Therefore, the new simulation and navigation system can be judged to be a powerful operative supporting modality for correcting the locations of cerebral lesions; it allows one to perform stereotactic surgery more accurately and less invasively. (author)

  7. The research of Digital Holographic Object Wave Field Reconstruction in Image and Object Space

    Institute of Scientific and Technical Information of China (English)

    LI Jun-Chang; PENG Zu-Jie; FU Yun-Chang

    2011-01-01

    @@ For conveniently detecting objects of different sizes using digital holography, usual measurements employ the object wave transformed by an optical system with different magnifications to fit charge coupled devices (CCDs), then the object field reconstruction involves the diffraction calculation of the optic wave passing through the optical system.We propose two methods to reconstruct the object field.The one is that, when the object is imaging in an image space in which we reconstruct the image of the object field, the object field can be expressed according to the object-image relationship.The other is that, when the object field reaching CCD is imaged in an object space in which we reconstruct the object field, the optical system is described by introducing matrix optics in this paper.The reconstruction formulae which easily use classic diffraction integral are derived.Finally, experimental verifications are also accomplished.%For conveniently detecting objects of different sizes using digital holography, usual measurements employ the object wave transformed by an optical system with different magnifications to fit charge coupled devices (CCDs), then the object Reid reconstruction involves the diffraction calculation of the optic wave passing through the optical system. We propose two methods to reconstruct the object field. The one is that, when the object is imaging in an image space in which we reconstruct the image of the object field, the object field can be expressed according to the object-image relationship. The other is that, when the object field reaching CCD is imaged in an object space in which we reconstruct the object field, the optical system is described by introducing matrix optics in this paper. The reconstruction formulae which easily use classic diffraction integral are derived. Finally, experimental verifications are also accomplished.

  8. Choice of reconstructed tissue properties affects interpretation of lung EIT images.

    Science.gov (United States)

    Grychtol, Bartłomiej; Adler, Andy

    2014-06-01

    Electrical impedance tomography (EIT) estimates an image of change in electrical properties within a body from stimulations and measurements at surface electrodes. There is significant interest in EIT as a tool to monitor and guide ventilation therapy in mechanically ventilated patients. In lung EIT, the EIT inverse problem is commonly linearized and only changes in electrical properties are reconstructed. Early algorithms reconstructed changes in resistivity, while most recent work using the finite element method reconstructs conductivity. Recently, we demonstrated that EIT images of ventilation can be misleading if the electrical contrasts within the thorax are not taken into account during the image reconstruction process. In this paper, we explore the effect of the choice of the reconstructed electrical properties (resistivity or conductivity) on the resulting EIT images. We show in simulation and experimental data that EIT images reconstructed with the same algorithm but with different parametrizations lead to large and clinically significant differences in the resulting images, which persist even after attempts to eliminate the impact of the parameter choice by recovering volume changes from the EIT images. Since there is no consensus among the most popular reconstruction algorithms and devices regarding the parametrization, this finding has implications for potential clinical use of EIT. We propose a program of research to develop reconstruction techniques that account for both the relationship between air volume and electrical properties of the lung and artefacts introduced by the linearization.

  9. Choice of reconstructed tissue properties affects interpretation of lung EIT images

    International Nuclear Information System (INIS)

    Grychtol, Bartłomiej; Adler, Andy

    2014-01-01

    Electrical impedance tomography (EIT) estimates an image of change in electrical properties within a body from stimulations and measurements at surface electrodes. There is significant interest in EIT as a tool to monitor and guide ventilation therapy in mechanically ventilated patients. In lung EIT, the EIT inverse problem is commonly linearized and only changes in electrical properties are reconstructed. Early algorithms reconstructed changes in resistivity, while most recent work using the finite element method reconstructs conductivity. Recently, we demonstrated that EIT images of ventilation can be misleading if the electrical contrasts within the thorax are not taken into account during the image reconstruction process. In this paper, we explore the effect of the choice of the reconstructed electrical properties (resistivity or conductivity) on the resulting EIT images. We show in simulation and experimental data that EIT images reconstructed with the same algorithm but with different parametrizations lead to large and clinically significant differences in the resulting images, which persist even after attempts to eliminate the impact of the parameter choice by recovering volume changes from the EIT images. Since there is no consensus among the most popular reconstruction algorithms and devices regarding the parametrization, this finding has implications for potential clinical use of EIT. We propose a program of research to develop reconstruction techniques that account for both the relationship between air volume and electrical properties of the lung and artefacts introduced by the linearization. (paper)

  10. Multi-view Multi-sparsity Kernel Reconstruction for Multi-class Image Classification

    KAUST Repository

    Zhu, Xiaofeng

    2015-05-28

    This paper addresses the problem of multi-class image classification by proposing a novel multi-view multi-sparsity kernel reconstruction (MMKR for short) model. Given images (including test images and training images) representing with multiple visual features, the MMKR first maps them into a high-dimensional space, e.g., a reproducing kernel Hilbert space (RKHS), where test images are then linearly reconstructed by some representative training images, rather than all of them. Furthermore a classification rule is proposed to classify test images. Experimental results on real datasets show the effectiveness of the proposed MMKR while comparing to state-of-the-art algorithms.

  11. Electro-optical system for the high speed reconstruction of computed tomography images

    International Nuclear Information System (INIS)

    Tresp, V.

    1989-01-01

    An electro-optical system for the high-speed reconstruction of computed tomography (CT) images has been built and studied. The system is capable of reconstructing high-contrast and high-resolution images at video rate (30 images per second), which is more than two orders of magnitude faster than the reconstruction rate achieved by special purpose digital computers used in commercial CT systems. The filtered back-projection algorithm which was implemented in the reconstruction system requires the filtering of all projections with a prescribed filter function. A space-integrating acousto-optical convolver, a surface acoustic wave filter and a digital finite-impulse response filter were used for this purpose and their performances were compared. The second part of the reconstruction, the back projection of the filtered projections, is computationally very expensive. An optical back projector has been built which maps the filtered projections onto the two-dimensional image space using an anamorphic lens system and a prism image rotator. The reconstructed image is viewed by a video camera, routed through a real-time image-enhancement system, and displayed on a TV monitor. The system reconstructs parallel-beam projection data, and in a modified version, is also capable of reconstructing fan-beam projection data. This extension is important since the latter are the kind of projection data actually acquired in high-speed X-ray CT scanners. The reconstruction system was tested by reconstructing precomputed projection data of phantom images. These were stored in a special purpose projection memory and transmitted to the reconstruction system as an electronic signal. In this way, a projection measurement system that acquires projections sequentially was simulated

  12. SU-E-I-73: Clinical Evaluation of CT Image Reconstructed Using Interior Tomography

    International Nuclear Information System (INIS)

    Zhang, J; Ge, G; Winkler, M; Cong, W; Wang, G

    2014-01-01

    Purpose: Radiation dose reduction has been a long standing challenge in CT imaging of obese patients. Recent advances in interior tomography (reconstruction of an interior region of interest (ROI) from line integrals associated with only paths through the ROI) promise to achieve significant radiation dose reduction without compromising image quality. This study is to investigate the application of this technique in CT imaging through evaluating imaging quality reconstructed from patient data. Methods: Projection data were directly obtained from patients who had CT examinations in a Dual Source CT scanner (DSCT). Two detectors in a DSCT acquired projection data simultaneously. One detector provided projection data for full field of view (FOV, 50 cm) while another detectors provided truncated projection data for a FOV of 26 cm. Full FOV CT images were reconstructed using both filtered back projection and iterative algorithm; while interior tomography algorithm was implemented to reconstruct ROI images. For comparison reason, FBP was also used to reconstruct ROI images. Reconstructed CT images were evaluated by radiologists and compared with images from CT scanner. Results: The results show that the reconstructed ROI image was in excellent agreement with the truth inside the ROI, obtained from images from CT scanner, and the detailed features in the ROI were quantitatively accurate. Radiologists evaluation shows that CT images reconstructed with interior tomography met diagnosis requirements. Radiation dose may be reduced up to 50% using interior tomography, depending on patient size. Conclusion: This study shows that interior tomography can be readily employed in CT imaging for radiation dose reduction. It may be especially useful in imaging obese patients, whose subcutaneous tissue is less clinically relevant but may significantly increase radiation dose

  13. Model-Based Photoacoustic Image Reconstruction using Compressed Sensing and Smoothed L0 Norm

    OpenAIRE

    Mozaffarzadeh, Moein; Mahloojifar, Ali; Nasiriavanaki, Mohammadreza; Orooji, Mahdi

    2018-01-01

    Photoacoustic imaging (PAI) is a novel medical imaging modality that uses the advantages of the spatial resolution of ultrasound imaging and the high contrast of pure optical imaging. Analytical algorithms are usually employed to reconstruct the photoacoustic (PA) images as a result of their simple implementation. However, they provide a low accurate image. Model-based (MB) algorithms are used to improve the image quality and accuracy while a large number of transducers and data acquisition a...

  14. Magni: A Python Package for Compressive Sampling and Reconstruction of Atomic Force Microscopy Images

    Directory of Open Access Journals (Sweden)

    Christian Schou Oxvig

    2014-10-01

    Full Text Available Magni is an open source Python package that embraces compressed sensing and Atomic Force Microscopy (AFM imaging techniques. It provides AFM-specific functionality for undersampling and reconstructing images from AFM equipment and thereby accelerating the acquisition of AFM images. Magni also provides researchers in compressed sensing with a selection of algorithms for reconstructing undersampled general images, and offers a consistent and rigorous way to efficiently evaluate the researchers own developed reconstruction algorithms in terms of phase transitions. The package also serves as a convenient platform for researchers in compressed sensing aiming at obtaining a high degree of reproducibility of their research.

  15. An iterative reconstruction method of complex images using expectation maximization for radial parallel MRI

    International Nuclear Information System (INIS)

    Choi, Joonsung; Kim, Dongchan; Oh, Changhyun; Han, Yeji; Park, HyunWook

    2013-01-01

    In MRI (magnetic resonance imaging), signal sampling along a radial k-space trajectory is preferred in certain applications due to its distinct advantages such as robustness to motion, and the radial sampling can be beneficial for reconstruction algorithms such as parallel MRI (pMRI) due to the incoherency. For radial MRI, the image is usually reconstructed from projection data using analytic methods such as filtered back-projection or Fourier reconstruction after gridding. However, the quality of the reconstructed image from these analytic methods can be degraded when the number of acquired projection views is insufficient. In this paper, we propose a novel reconstruction method based on the expectation maximization (EM) method, where the EM algorithm is remodeled for MRI so that complex images can be reconstructed. Then, to optimize the proposed method for radial pMRI, a reconstruction method that uses coil sensitivity information of multichannel RF coils is formulated. Experiment results from synthetic and in vivo data show that the proposed method introduces better reconstructed images than the analytic methods, even from highly subsampled data, and provides monotonic convergence properties compared to the conjugate gradient based reconstruction method. (paper)

  16. A BPF-FBP tandem algorithm for image reconstruction in reverse helical cone-beam CT

    International Nuclear Information System (INIS)

    Cho, Seungryong; Xia, Dan; Pellizzari, Charles A.; Pan Xiaochuan

    2010-01-01

    Purpose: Reverse helical cone-beam computed tomography (CBCT) is a scanning configuration for potential applications in image-guided radiation therapy in which an accurate anatomic image of the patient is needed for image-guidance procedures. The authors previously developed an algorithm for image reconstruction from nontruncated data of an object that is completely within the reverse helix. The purpose of this work is to develop an image reconstruction approach for reverse helical CBCT of a long object that extends out of the reverse helix and therefore constitutes data truncation. Methods: The proposed approach comprises of two reconstruction steps. In the first step, a chord-based backprojection-filtration (BPF) algorithm reconstructs a volumetric image of an object from the original cone-beam data. Because there exists a chordless region in the middle of the reverse helix, the image obtained in the first step contains an unreconstructed central-gap region. In the second step, the gap region is reconstructed by use of a Pack-Noo-formula-based filteredbackprojection (FBP) algorithm from the modified cone-beam data obtained by subtracting from the original cone-beam data the reprojection of the image reconstructed in the first step. Results: The authors have performed numerical studies to validate the proposed approach in image reconstruction from reverse helical cone-beam data. The results confirm that the proposed approach can reconstruct accurate images of a long object without suffering from data-truncation artifacts or cone-angle artifacts. Conclusions: They developed and validated a BPF-FBP tandem algorithm to reconstruct images of a long object from reverse helical cone-beam data. The chord-based BPF algorithm was utilized for converting the long-object problem into a short-object problem. The proposed approach is applicable to other scanning configurations such as reduced circular sinusoidal trajectories.

  17. Real-time SPARSE-SENSE cardiac cine MR imaging: optimization of image reconstruction and sequence validation.

    Science.gov (United States)

    Goebel, Juliane; Nensa, Felix; Bomas, Bettina; Schemuth, Haemi P; Maderwald, Stefan; Gratz, Marcel; Quick, Harald H; Schlosser, Thomas; Nassenstein, Kai

    2016-12-01

    Improved real-time cardiac magnetic resonance (CMR) sequences have currently been introduced, but so far only limited practical experience exists. This study aimed at image reconstruction optimization and clinical validation of a new highly accelerated real-time cine SPARSE-SENSE sequence. Left ventricular (LV) short-axis stacks of a real-time free-breathing SPARSE-SENSE sequence with high spatiotemporal resolution and of a standard segmented cine SSFP sequence were acquired at 1.5 T in 11 volunteers and 15 patients. To determine the optimal iterations, all volunteers' SPARSE-SENSE images were reconstructed using 10-200 iterations, and contrast ratios, image entropies, and reconstruction times were assessed. Subsequently, the patients' SPARSE-SENSE images were reconstructed with the clinically optimal iterations. LV volumetric values were evaluated and compared between both sequences. Sufficient image quality and acceptable reconstruction times were achieved when using 80 iterations. Bland-Altman plots and Passing-Bablok regression showed good agreement for all volumetric parameters. 80 iterations are recommended for iterative SPARSE-SENSE image reconstruction in clinical routine. Real-time cine SPARSE-SENSE yielded comparable volumetric results as the current standard SSFP sequence. Due to its intrinsic low image acquisition times, real-time cine SPARSE-SENSE imaging with iterative image reconstruction seems to be an attractive alternative for LV function analysis. • A highly accelerated real-time CMR sequence using SPARSE-SENSE was evaluated. • SPARSE-SENSE allows free breathing in real-time cardiac cine imaging. • For clinically optimal SPARSE-SENSE image reconstruction, 80 iterations are recommended. • Real-time SPARSE-SENSE imaging yielded comparable volumetric results as the reference SSFP sequence. • The fast SPARSE-SENSE sequence is an attractive alternative to standard SSFP sequences.

  18. Recent improvements in Hurricane Imaging Radiometer’s brightness temperature image reconstruction

    Directory of Open Access Journals (Sweden)

    Sayak K. Biswas

    Full Text Available NASA MSFCs airborne Hurricane Imaging Radiometer (HIRAD uses interferometric aperture synthesis to produce high resolution wide swath images of scene brightness temperature (Tb distribution at four discrete C-band microwave frequencies (4.0, 5.0, 6.0 and 6.6 GHz. Images of ocean surface wind speed under heavy precipitation such as in tropical cyclones, is inferred from these measurements. The baseline HIRAD Tb reconstruction algorithm had produced prominent along-track streaks in the Tb images. Particularly the 4.0 GHz channel had been so dominated by the streaks as to be unusable.The loss of a frequency channel had compromised the final wind speed retrievals. During 2016, the HIRAD team made substantial progress in developing a quality controlled signal processing technique for the HIRAD data collected in 2015’s Tropical Cyclone Intensity (TCI experiment and reduced the effect of streaks in all channels including 4.0 GHz. 2000 MSC: 41A05, 41A10, 65D05, 65D17, Keywords: Microwave radiometry, Aperture synthesis, Image reconstruction, Hurricane winds

  19. PIRPLE: a penalized-likelihood framework for incorporation of prior images in CT reconstruction

    International Nuclear Information System (INIS)

    Stayman, J Webster; Dang, Hao; Ding, Yifu; Siewerdsen, Jeffrey H

    2013-01-01

    Over the course of diagnosis and treatment, it is common for a number of imaging studies to be acquired. Such imaging sequences can provide substantial patient-specific prior knowledge about the anatomy that can be incorporated into a prior-image-based tomographic reconstruction for improved image quality and better dose utilization. We present a general methodology using a model-based reconstruction approach including formulations of the measurement noise that also integrates prior images. This penalized-likelihood technique adopts a sparsity enforcing penalty that incorporates prior information yet allows for change between the current reconstruction and the prior image. Moreover, since prior images are generally not registered with the current image volume, we present a modified model-based approach that seeks a joint registration of the prior image in addition to the reconstruction of projection data. We demonstrate that the combined prior-image- and model-based technique outperforms methods that ignore the prior data or lack a noise model. Moreover, we demonstrate the importance of registration for prior-image-based reconstruction methods and show that the prior-image-registered penalized-likelihood estimation (PIRPLE) approach can maintain a high level of image quality in the presence of noisy and undersampled projection data. (paper)

  20. Linearized image reconstruction method for ultrasound modulated electrical impedance tomography based on power density distribution

    International Nuclear Information System (INIS)

    Song, Xizi; Xu, Yanbin; Dong, Feng

    2017-01-01

    Electrical resistance tomography (ERT) is a promising measurement technique with important industrial and clinical applications. However, with limited effective measurements, it suffers from poor spatial resolution due to the ill-posedness of the inverse problem. Recently, there has been an increasing research interest in hybrid imaging techniques, utilizing couplings of physical modalities, because these techniques obtain much more effective measurement information and promise high resolution. Ultrasound modulated electrical impedance tomography (UMEIT) is one of the newly developed hybrid imaging techniques, which combines electric and acoustic modalities. A linearized image reconstruction method based on power density is proposed for UMEIT. The interior data, power density distribution, is adopted to reconstruct the conductivity distribution with the proposed image reconstruction method. At the same time, relating the power density change to the change in conductivity, the Jacobian matrix is employed to make the nonlinear problem into a linear one. The analytic formulation of this Jacobian matrix is derived and its effectiveness is also verified. In addition, different excitation patterns are tested and analyzed, and opposite excitation provides the best performance with the proposed method. Also, multiple power density distributions are combined to implement image reconstruction. Finally, image reconstruction is implemented with the linear back-projection (LBP) algorithm. Compared with ERT, with the proposed image reconstruction method, UMEIT can produce reconstructed images with higher quality and better quantitative evaluation results. (paper)

  1. A Superresolution Image Reconstruction Algorithm Based on Landweber in Electrical Capacitance Tomography

    Directory of Open Access Journals (Sweden)

    Chen Deyun

    2013-01-01

    Full Text Available According to the image reconstruction accuracy influenced by the “soft field” nature and ill-conditioned problems in electrical capacitance tomography, a superresolution image reconstruction algorithm based on Landweber is proposed in the paper, which is based on the working principle of the electrical capacitance tomography system. The method uses the algorithm which is derived by regularization of solutions derived and derives closed solution by fast Fourier transform of the convolution kernel. So, it ensures the certainty of the solution and improves the stability and quality of image reconstruction results. Simulation results show that the imaging precision and real-time imaging of the algorithm are better than Landweber algorithm, and this algorithm proposes a new method for the electrical capacitance tomography image reconstruction algorithm.

  2. Robust framework for PET image reconstruction incorporating system and measurement uncertainties.

    Directory of Open Access Journals (Sweden)

    Huafeng Liu

    Full Text Available In Positron Emission Tomography (PET, an optimal estimate of the radioactivity concentration is obtained from the measured emission data under certain criteria. So far, all the well-known statistical reconstruction algorithms require exactly known system probability matrix a priori, and the quality of such system model largely determines the quality of the reconstructed images. In this paper, we propose an algorithm for PET image reconstruction for the real world case where the PET system model is subject to uncertainties. The method counts PET reconstruction as a regularization problem and the image estimation is achieved by means of an uncertainty weighted least squares framework. The performance of our work is evaluated with the Shepp-Logan simulated and real phantom data, which demonstrates significant improvements in image quality over the least squares reconstruction efforts.

  3. Imaging features of anterior cruciate ligament reconstruction graft insufficiency

    International Nuclear Information System (INIS)

    Shang Yao; Zhang Yue; Tian Chunyan; Zheng Zhuozhao

    2011-01-01

    Objective: To investigate the imaging features of anterior cruciate ligament (ACL) graft insufficiency. Methods: X-Ray and MR imaging examinations in 24 consecutive patients who had ACL reconstructive graft insufficiency were retrospectively evaluated for tunnel position, osteoarthrosis and its related complications. Follow-up arthroscopy showed 16 graft tears and 8 graft laxities. Fisher exact test was used to compare tunnel malpositions, the proportion of graft tear on MRI and osteoarthrosis between graft tear group and graft laxity group. Results: Two malpositions of tibial tunnel and 3 malpositions of femoral tunnel were seen in graft tear group. Three-malpositions of tibial tunnel and 4 malpositions of femoral tunnel were seen in graft laxity group. The proportion of tibial or femoral malposition showed no significant difference between the two groups (P=0.289, P=0.167). In graft tear group, 15 complete graft tears were diagnosed correctly, 1 partial tear was misdiagnosed as normal on MRI. In graft laxity group, 4 grafts were diagnosed as normal and 4 were considered as graft tear on MRI. A significant difference was seen between the two groups (P=0.028) in the proportion of graft tear diagnosed on MRI. Fourteen osteoarthrosis were seen in graft tear group and 5 in graft laxity group. No significant difference was seen between the two groups (P= 0.289) in the proportion of osteoarthrosis. Conclusion: The proportions of tunnel malposition and osteoarthrosis showed no significant difference between the graft tear group and graft Laxity group. Most graft tears can be diagnosed accurately on MRI, but some cases of graft laxity may be misdiagnosed for graft tear. (authors)

  4. Positron transaxial emission tomograph with computerized image reconstruction

    International Nuclear Information System (INIS)

    Jatteau, Michel.

    1981-01-01

    This invention concerns a positron transaxial emission tomography apparatus with computerized image reconstruction, like those used in nuclear medicine for studying the metabolism of organs, in physiological examinations and as a diagnosis aid. The operation is based on the principle of the detection of photons emitted when the positrons are annihilated by impact with an electron. The appliance is mainly composed of: (a) - a set of gamma ray detectors distributed on a polygonal arrangement around the body area to be examined, (b) - circuits for amplifying the signals delivered by the gamma ray detectors, (c) - computers essentially comprising energy integration and discrimination circuits and provided at the output of the detectors for calculating and delivering, as from the amplified signals, information on the position and energy relative to each occurrence constituted by the detections of photons, (d) - time coincidence circuits for selecting by emission of detector validation signals, only those occurrences, among the ensemble of those detected, which effectively result from the annihilation of positrons inside the area examined, (e) - a data processing system [fr

  5. An efficient algorithm for reconstruction of spect images in the presence of spatially varying attenuation

    International Nuclear Information System (INIS)

    Zeeberg, B.R.; Bacharach, S.; Carson, R.; Green, M.V.; Larson, S.M.; Soucaille, J.F.

    1985-01-01

    An algorithm is presented which permits the reconstruction of SPECT images in the presence of spatially varying attenuation. The algorithm considers the spatially variant attenuation as a perturbation of the constant attenuation case and computes a reconstructed image and a correction image to estimate the effects of this perturbation. The corrected image will be computed from these two images and is of comparable quality both visually and quantitatively to those simulated for zero or constant attenuation taken as standard reference images. In addition, the algorithm is time efficient, in that the time required is approximately 2.5 times that for a standard convolution-back projection algorithm

  6. Sparsity-promoting orthogonal dictionary updating for image reconstruction from highly undersampled magnetic resonance data

    International Nuclear Information System (INIS)

    Huang, Jinhong; Guo, Li; Feng, Qianjin; Chen, Wufan; Feng, Yanqiu

    2015-01-01

    Image reconstruction from undersampled k-space data accelerates magnetic resonance imaging (MRI) by exploiting image sparseness in certain transform domains. Employing image patch representation over a learned dictionary has the advantage of being adaptive to local image structures and thus can better sparsify images than using fixed transforms (e.g. wavelets and total variations). Dictionary learning methods have recently been introduced to MRI reconstruction, and these methods demonstrate significantly reduced reconstruction errors compared to sparse MRI reconstruction using fixed transforms. However, the synthesis sparse coding problem in dictionary learning is NP-hard and computationally expensive. In this paper, we present a novel sparsity-promoting orthogonal dictionary updating method for efficient image reconstruction from highly undersampled MRI data. The orthogonality imposed on the learned dictionary enables the minimization problem in the reconstruction to be solved by an efficient optimization algorithm which alternately updates representation coefficients, orthogonal dictionary, and missing k-space data. Moreover, both sparsity level and sparse representation contribution using updated dictionaries gradually increase during iterations to recover more details, assuming the progressively improved quality of the dictionary. Simulation and real data experimental results both demonstrate that the proposed method is approximately 10 to 100 times faster than the K-SVD-based dictionary learning MRI method and simultaneously improves reconstruction accuracy. (paper)

  7. Sparsity-promoting orthogonal dictionary updating for image reconstruction from highly undersampled magnetic resonance data.

    Science.gov (United States)

    Huang, Jinhong; Guo, Li; Feng, Qianjin; Chen, Wufan; Feng, Yanqiu

    2015-07-21

    Image reconstruction from undersampled k-space data accelerates magnetic resonance imaging (MRI) by exploiting image sparseness in certain transform domains. Employing image patch representation over a learned dictionary has the advantage of being adaptive to local image structures and thus can better sparsify images than using fixed transforms (e.g. wavelets and total variations). Dictionary learning methods have recently been introduced to MRI reconstruction, and these methods demonstrate significantly reduced reconstruction errors compared to sparse MRI reconstruction using fixed transforms. However, the synthesis sparse coding problem in dictionary learning is NP-hard and computationally expensive. In this paper, we present a novel sparsity-promoting orthogonal dictionary updating method for efficient image reconstruction from highly undersampled MRI data. The orthogonality imposed on the learned dictionary enables the minimization problem in the reconstruction to be solved by an efficient optimization algorithm which alternately updates representation coefficients, orthogonal dictionary, and missing k-space data. Moreover, both sparsity level and sparse representation contribution using updated dictionaries gradually increase during iterations to recover more details, assuming the progressively improved quality of the dictionary. Simulation and real data experimental results both demonstrate that the proposed method is approximately 10 to 100 times faster than the K-SVD-based dictionary learning MRI method and simultaneously improves reconstruction accuracy.

  8. A comparative study of three-dimensional reconstructive images of temporomandibular joint using computed tomogram

    International Nuclear Information System (INIS)

    Lim, Suk Young; Koh, Kwang Joon

    1993-01-01

    The purpose of this study was to clarify the spatial relationship of temporomandibular joint and to an aid in the diagnosis of temporomandibular disorder. For this study, three-dimensional images of normal temporomandibular joint were reconstructed by computer image analysis system and three-dimensional reconstructive program integrated in computed tomography. The obtained results were as follows : 1. Two-dimensional computed tomograms had the better resolution than three dimensional computed tomograms in the evaluation of bone structure and the disk of TMJ. 2. Direct sagittal computed tomograms and coronal computed tomograms had the better resolution in the evaluation of the disk of TMJ. 3. The positional relationship of the disk could be visualized, but the configuration of the disk could not be clearly visualized on three-dimensional reconstructive CT images. 4. Three-dimensional reconstructive CT images had the smoother margin than three-dimensional images reconstructed by computer image analysis system, but the images of the latter had the better perspective. 5. Three-dimensional reconstructive images had the better spatial relationship of the TMJ articulation, and the joint space were more clearly visualized on dissection images.

  9. Multiple-image hiding using super resolution reconstruction in high-frequency domains

    Science.gov (United States)

    Li, Xiao-Wei; Zhao, Wu-Xiang; Wang, Jun; Wang, Qiong-Hua

    2017-12-01

    In this paper, a robust multiple-image hiding method using the computer-generated integral imaging and the modified super-resolution reconstruction algorithm is proposed. In our work, the host image is first transformed into frequency domains by cellular automata (CA), to assure the quality of the stego-image, the secret images are embedded into the CA high-frequency domains. The proposed method has the following advantages: (1) robustness to geometric attacks because of the memory-distributed property of elemental images, (2) increasing quality of the reconstructed secret images as the scheme utilizes the modified super-resolution reconstruction algorithm. The simulation results show that the proposed multiple-image hiding method outperforms other similar hiding methods and is robust to some geometric attacks, e.g., Gaussian noise and JPEG compression attacks.

  10. Synthetic biology's tall order: Reconstruction of 3D, super resolution images of single molecules in real-time

    CSIR Research Space (South Africa)

    Henriques, R

    2010-08-31

    Full Text Available -to-use reconstruction software coupled with image acquisition. Here, we present QuickPALM, an Image plugin, enabling real-time reconstruction of 3D super-resolution images during acquisition and drift correction. We illustrate its application by reconstructing Cy5...

  11. GPU-accelerated Kernel Regression Reconstruction for Freehand 3D Ultrasound Imaging.

    Science.gov (United States)

    Wen, Tiexiang; Li, Ling; Zhu, Qingsong; Qin, Wenjian; Gu, Jia; Yang, Feng; Xie, Yaoqin

    2017-07-01

    Volume reconstruction method plays an important role in improving reconstructed volumetric image quality for freehand three-dimensional (3D) ultrasound imaging. By utilizing the capability of programmable graphics processing unit (GPU), we can achieve a real-time incremental volume reconstruction at a speed of 25-50 frames per second (fps). After incremental reconstruction and visualization, hole-filling is performed on GPU to fill remaining empty voxels. However, traditional pixel nearest neighbor-based hole-filling fails to reconstruct volume with high image quality. On the contrary, the kernel regression provides an accurate volume reconstruction method for 3D ultrasound imaging but with the cost of heavy computational complexity. In this paper, a GPU-based fast kernel regression method is proposed for high-quality volume after the incremental reconstruction of freehand ultrasound. The experimental results show that improved image quality for speckle reduction and details preservation can be obtained with the parameter setting of kernel window size of [Formula: see text] and kernel bandwidth of 1.0. The computational performance of the proposed GPU-based method can be over 200 times faster than that on central processing unit (CPU), and the volume with size of 50 million voxels in our experiment can be reconstructed within 10 seconds.

  12. The value of spiral CT thin imaging reconstruction in the diagnosis of obstructive jaundice

    International Nuclear Information System (INIS)

    Huang Zhi; Liu Zhang; Yang Chaoxiang; Lin Chengye; Zhang Li; Li Yuxiang; Ma Yunyan; Xiao Haisong; Lu Zhifeng; Wang Bo; Zhou Yunhong

    2009-01-01

    Objective: To approach the value of spiral CT thin imaging reconstruction in the diagnosis of obstructive jaundice in order to improve the correctness of the diagnosis. Methods: Analysis the cases' clinical manifestation and the CT images, who were diagnosed as obstructive jaundice by operation. All of cases had high-resolution computed tomograyhy scan. The thickness and the interval is 5mm, reconstructed the thickness and the interval to 1 mm and 1.5 mm, then send the images to the workstation and MRR were processed. Analysis the date with the pathology. Results: Spiral CT thin imaging reconstruction have 98% and 93% in the accuracy of location and characterization in the obstruction. Conclusion: The spiral CT thin imaging reconstruction is a good method to improve the accuracy of location and characterization in the obstructive jaundice. (authors)

  13. Linear image reconstruction for a diffuse optical mammography system in a noncompressed geometry using scattering fluid

    International Nuclear Information System (INIS)

    Nielsen, Tim; Brendel, Bernhard; Ziegler, Ronny; Beek, Michiel van; Uhlemann, Falk; Bontus, Claas; Koehler, Thomas

    2009-01-01

    Diffuse optical tomography (DOT) is a potential new imaging modality to detect or monitor breast lesions. Recently, Philips developed a new DOT system capable of transmission and fluorescence imaging, where the investigated breast is hanging freely into the measurement cup containing scattering fluid. We present a fast and robust image reconstruction algorithm that is used for the transmission measurements. The algorithm is based on the Rytov approximation. We show that this algorithm can be used over a wide range of tissue optical properties if the reconstruction is adapted to each patient. We use estimates of the breast shape and average tissue optical properties to initialize the reconstruction, which improves the image quality significantly. We demonstrate the capability of the measurement system and reconstruction to image breast lesions by clinical examples

  14. Color quality improvement of reconstructed images in color digital holography using speckle method and spectral estimation

    Science.gov (United States)

    Funamizu, Hideki; Onodera, Yusei; Aizu, Yoshihisa

    2018-05-01

    In this study, we report color quality improvement of reconstructed images in color digital holography using the speckle method and the spectral estimation. In this technique, an object is illuminated by a speckle field and then an object wave is produced, while a plane wave is used as a reference wave. For three wavelengths, the interference patterns of two coherent waves are recorded as digital holograms on an image sensor. Speckle fields are changed by moving a ground glass plate in an in-plane direction, and a number of holograms are acquired to average the reconstructed images. After the averaging process of images reconstructed from multiple holograms, we use the Wiener estimation method for obtaining spectral transmittance curves in reconstructed images. The color reproducibility in this method is demonstrated and evaluated using a Macbeth color chart film and staining cells of onion.

  15. Three-dimensional reconstruction and visualization system for medical images

    International Nuclear Information System (INIS)

    Preston, D.F.; Batnitzky, S.; Kyo Rak Lee; Cook, P.N.; Cook, L.T.; Dwyer, S.J.

    1982-01-01

    A three-dimensional reconstruction and visualization system could be of significant advantage in medical application such as neurosurgery and radiation treatment planning. The reconstructed anatomic structures from CT head scans could be used in a head stereotactic system to help plan the surgical procedure and the radiation treatment for a brain lesion. Also, the use of three-dimensional reconstruction algorithm provides for quantitative measures such as volume and surface area estimation of the anatomic features. This aspect of the three-dimensional reconstruction system may be used to monitor the progress or staging of a disease and the effects of patient treatment. Two cases are presented to illustrate the three-dimensional surface reconstruction and visualization system

  16. Image alignment for tomography reconstruction from synchrotron X-ray microscopic images.

    Directory of Open Access Journals (Sweden)

    Chang-Chieh Cheng

    Full Text Available A synchrotron X-ray microscope is a powerful imaging apparatus for taking high-resolution and high-contrast X-ray images of nanoscale objects. A sufficient number of X-ray projection images from different angles is required for constructing 3D volume images of an object. Because a synchrotron light source is immobile, a rotational object holder is required for tomography. At a resolution of 10 nm per pixel, the vibration of the holder caused by rotating the object cannot be disregarded if tomographic images are to be reconstructed accurately. This paper presents a computer method to compensate for the vibration of the rotational holder by aligning neighboring X-ray images. This alignment process involves two steps. The first step is to match the "projected feature points" in the sequence of images. The matched projected feature points in the x-θ plane should form a set of sine-shaped loci. The second step is to fit the loci to a set of sine waves to compute the parameters required for alignment. The experimental results show that the proposed method outperforms two previously proposed methods, Xradia and SPIDER. The developed software system can be downloaded from the URL, http://www.cs.nctu.edu.tw/~chengchc/SCTA or http://goo.gl/s4AMx.

  17. Image alignment for tomography reconstruction from synchrotron X-ray microscopic images.

    Science.gov (United States)

    Cheng, Chang-Chieh; Chien, Chia-Chi; Chen, Hsiang-Hsin; Hwu, Yeukuang; Ching, Yu-Tai

    2014-01-01

    A synchrotron X-ray microscope is a powerful imaging apparatus for taking high-resolution and high-contrast X-ray images of nanoscale objects. A sufficient number of X-ray projection images from different angles is required for constructing 3D volume images of an object. Because a synchrotron light source is immobile, a rotational object holder is required for tomography. At a resolution of 10 nm per pixel, the vibration of the holder caused by rotating the object cannot be disregarded if tomographic images are to be reconstructed accurately. This paper presents a computer method to compensate for the vibration of the rotational holder by aligning neighboring X-ray images. This alignment process involves two steps. The first step is to match the "projected feature points" in the sequence of images. The matched projected feature points in the x-θ plane should form a set of sine-shaped loci. The second step is to fit the loci to a set of sine waves to compute the parameters required for alignment. The experimental results show that the proposed method outperforms two previously proposed methods, Xradia and SPIDER. The developed software system can be downloaded from the URL, http://www.cs.nctu.edu.tw/~chengchc/SCTA or http://goo.gl/s4AMx.

  18. Self-training-based spectral image reconstruction for art paintings with multispectral imaging.

    Science.gov (United States)

    Xu, Peng; Xu, Haisong; Diao, Changyu; Ye, Zhengnan

    2017-10-20

    A self-training-based spectral reflectance recovery method was developed to accurately reconstruct the spectral images of art paintings with multispectral imaging. By partitioning the multispectral images with the k-means clustering algorithm, the training samples are directly extracted from the art painting itself to restrain the deterioration of spectral estimation caused by the material inconsistency between the training samples and the art painting. Coordinate paper is used to locate the extracted training samples. The spectral reflectances of the extracted training samples are acquired indirectly with a spectroradiometer, and the circle Hough transform is adopted to detect the circle measuring area of the spectroradiometer. Through simulation and a practical experiment, the implementation of the proposed method is explained in detail, and it is verified to have better reflectance recovery performance than that using the commercial target and is comparable to the approach using a painted color target.

  19. A tensor-based dictionary learning approach to tomographic image reconstruction

    DEFF Research Database (Denmark)

    Soltani, Sara; Kilmer, Misha E.; Hansen, Per Christian

    2016-01-01

    We consider tomographic reconstruction using priors in the form of a dictionary learned from training images. The reconstruction has two stages: first we construct a tensor dictionary prior from our training data, and then we pose the reconstruction problem in terms of recovering the expansion...... coefficients in that dictionary. Our approach differs from past approaches in that (a) we use a third-order tensor representation for our images and (b) we recast the reconstruction problem using the tensor formulation. The dictionary learning problem is presented as a non-negative tensor factorization problem...... with sparsity constraints. The reconstruction problem is formulated in a convex optimization framework by looking for a solution with a sparse representation in the tensor dictionary. Numerical results show that our tensor formulation leads to very sparse representations of both the training images...

  20. Incorporation of local dependent reliability information into the Prior Image Constrained Compressed Sensing (PICCS) reconstruction algorithm

    International Nuclear Information System (INIS)

    Vaegler, Sven; Sauer, Otto; Stsepankou, Dzmitry; Hesser, Juergen

    2015-01-01

    The reduction of dose in cone beam computer tomography (CBCT) arises from the decrease of the tube current for each projection as well as from the reduction of the number of projections. In order to maintain good image quality, sophisticated image reconstruction techniques are required. The Prior Image Constrained Compressed Sensing (PICCS) incorporates prior images into the reconstruction algorithm and outperforms the widespread used Feldkamp-Davis-Kress-algorithm (FDK) when the number of projections is reduced. However, prior images that contain major variations are not appropriately considered so far in PICCS. We therefore propose the partial-PICCS (pPICCS) algorithm. This framework is a problem-specific extension of PICCS and enables the incorporation of the reliability of the prior images additionally. We assumed that the prior images are composed of areas with large and small deviations. Accordingly, a weighting matrix considered the assigned areas in the objective function. We applied our algorithm to the problem of image reconstruction from few views by simulations with a computer phantom as well as on clinical CBCT projections from a head-and-neck case. All prior images contained large local variations. The reconstructed images were compared to the reconstruction results by the FDK-algorithm, by Compressed Sensing (CS) and by PICCS. To show the gain of image quality we compared image details with the reference image and used quantitative metrics (root-mean-square error (RMSE), contrast-to-noise-ratio (CNR)). The pPICCS reconstruction framework yield images with substantially improved quality even when the number of projections was very small. The images contained less streaking, blurring and inaccurately reconstructed structures compared to the images reconstructed by FDK, CS and conventional PICCS. The increased image quality is also reflected in large RMSE differences. We proposed a modification of the original PICCS algorithm. The pPICCS algorithm

  1. Evaluation of image reconstruction methods for 123I-MIBG-SPECT. A rank-order study

    International Nuclear Information System (INIS)

    Soederberg, Marcus; Mattsson, Soeren; Oddstig, Jenny; Uusijaervi-Lizana, Helena; Leide-Svegborn, Sigrid; Valind, Sven; Thorsson, Ola; Garpered, Sabine; Prautzsch, Tilmann; Tischenko, Oleg

    2012-01-01

    Background: There is an opportunity to improve the image quality and lesion detectability in single photon emission computed tomography (SPECT) by choosing an appropriate reconstruction method and optimal parameters for the reconstruction. Purpose: To optimize the use of the Flash 3D reconstruction algorithm in terms of equivalent iteration (EI) number (number of subsets times the number of iterations) and to compare with two recently developed reconstruction algorithms ReSPECT and orthogonal polynomial expansion on disc (OPED) for application on 123 I-metaiodobenzylguanidine (MIBG)-SPECT. Material and Methods: Eleven adult patients underwent SPECT 4 h and 14 patients 24 h after injection of approximately 200 MBq 123 I-MIBG using a Siemens Symbia T6 SPECT/CT. Images were reconstructed from raw data using the Flash 3D algorithm at eight different EI numbers. The images were ranked by three experienced nuclear medicine physicians according to their overall impression of the image quality. The obtained optimal images were then compared in one further visual comparison with images reconstructed using the ReSPECT and OPED algorithms. Results: The optimal EI number for Flash 3D was determined to be 32 for acquisition 4 h and 24 h after injection. The average rank order (best first) for the different reconstructions for acquisition after 4 h was: Flash 3D 32 > ReSPECT > Flash 3D 64 > OPED, and after 24 h: Flash 3D 16 > ReSPECT > Flash 3D 32 > OPED. A fair level of inter-observer agreement concerning optimal EI number and reconstruction algorithm was obtained, which may be explained by the different individual preferences of what is appropriate image quality. Conclusion: Using Siemens Symbia T6 SPECT/CT and specified acquisition parameters, Flash 3D 32 (4 h) and Flash 3D 16 (24 h), followed by ReSPECT, were assessed to be the preferable reconstruction algorithms in visual assessment of 123 I-MIBG images

  2. MRI reconstruction of multi-image acquisitions using a rank regularizer with data reordering

    Energy Technology Data Exchange (ETDEWEB)

    Adluru, Ganesh, E-mail: gadluru@gmail.com; Anderson, Jeffrey [UCAIR, Department of Radiology, University of Utah, Salt Lake City, Utah 84108 (United States); Gur, Yaniv [IBM Almaden Research Center, San Jose, California 95120 (United States); Chen, Liyong; Feinberg, David [Advanced MRI Technologies, Sebastpool, California, 95472 (United States); DiBella, Edward V. R. [UCAIR, Department of Radiology, University of Utah, Salt Lake City, Utah 84108 and Department of Bioengineering, University of Utah, Salt Lake City, Utah 84112 (United States)

    2015-08-15

    Purpose: To improve rank constrained reconstructions for undersampled multi-image MRI acquisitions. Methods: Motivated by the recent developments in low-rank matrix completion theory and its applicability to rapid dynamic MRI, a new reordering-based rank constrained reconstruction of undersampled multi-image data that uses prior image information is proposed. Instead of directly minimizing the nuclear norm of a matrix of estimated images, the nuclear norm of reordered matrix values is minimized. The reordering is based on the prior image estimates. The method is tested on brain diffusion imaging data and dynamic contrast enhanced myocardial perfusion data. Results: Good quality images from data undersampled by a factor of three for diffusion imaging and by a factor of 3.5 for dynamic cardiac perfusion imaging with respiratory motion were obtained. Reordering gave visually improved image quality over standard nuclear norm minimization reconstructions. Root mean squared errors with respect to ground truth images were improved by ∼18% and ∼16% with reordering for diffusion and perfusion applications, respectively. Conclusions: The reordered low-rank constraint is a way to inject prior image information that offers improvements over a standard low-rank constraint for undersampled multi-image MRI reconstructions.

  3. MRI reconstruction of multi-image acquisitions using a rank regularizer with data reordering

    International Nuclear Information System (INIS)

    Adluru, Ganesh; Anderson, Jeffrey; Gur, Yaniv; Chen, Liyong; Feinberg, David; DiBella, Edward V. R.

    2015-01-01

    Purpose: To improve rank constrained reconstructions for undersampled multi-image MRI acquisitions. Methods: Motivated by the recent developments in low-rank matrix completion theory and its applicability to rapid dynamic MRI, a new reordering-based rank constrained reconstruction of undersampled multi-image data that uses prior image information is proposed. Instead of directly minimizing the nuclear norm of a matrix of estimated images, the nuclear norm of reordered matrix values is minimized. The reordering is based on the prior image estimates. The method is tested on brain diffusion imaging data and dynamic contrast enhanced myocardial perfusion data. Results: Good quality images from data undersampled by a factor of three for diffusion imaging and by a factor of 3.5 for dynamic cardiac perfusion imaging with respiratory motion were obtained. Reordering gave visually improved image quality over standard nuclear norm minimization reconstructions. Root mean squared errors with respect to ground truth images were improved by ∼18% and ∼16% with reordering for diffusion and perfusion applications, respectively. Conclusions: The reordered low-rank constraint is a way to inject prior image information that offers improvements over a standard low-rank constraint for undersampled multi-image MRI reconstructions

  4. Fan-beam and cone-beam image reconstruction via filtering the backprojection image of differentiated projection data

    International Nuclear Information System (INIS)

    Zhuang Tingliang; Leng Shuai; Nett, Brian E; Chen Guanghong

    2004-01-01

    In this paper, a new image reconstruction scheme is presented based on Tuy's cone-beam inversion scheme and its fan-beam counterpart. It is demonstrated that Tuy's inversion scheme may be used to derive a new framework for fan-beam and cone-beam image reconstruction. In this new framework, images are reconstructed via filtering the backprojection image of differentiated projection data. The new framework is mathematically exact and is applicable to a general source trajectory provided the Tuy data sufficiency condition is satisfied. By choosing a piece-wise constant function for one of the components in the factorized weighting function, the filtering kernel is one dimensional, viz. the filtering process is along a straight line. Thus, the derived image reconstruction algorithm is mathematically exact and efficient. In the cone-beam case, the derived reconstruction algorithm is applicable to a large class of source trajectories where the pi-lines or the generalized pi-lines exist. In addition, the new reconstruction scheme survives the super-short scan mode in both the fan-beam and cone-beam cases provided the data are not transversely truncated. Numerical simulations were conducted to validate the new reconstruction scheme for the fan-beam case

  5. CT coronary angiography: Influence of different cardiac reconstruction intervals on image quality and diagnostic accuracy

    Energy Technology Data Exchange (ETDEWEB)

    Dewey, Marc [Department of Radiology, Charite Medical School, Humboldt-Universitaet zu Berlin (Germany)], E-mail: marc.dewey@charite.de; Teige, Florian [Department of Radiology, Charite Medical School, Humboldt-Universitaet zu Berlin (Germany); Rutsch, Wolfgang [Department of Cardiology, Charite Medical School, Humboldt-Universitaet zu Berlin (Germany)], E-mail: wolfgang.rutsch@charite.de; Schink, Tania [Department of Medical Biometry, Charite Medical School, Humboldt-Universitaet zu Berlin (Germany)], E-mail: peter.martus@charite.de; Hamm, Bernd [Department of Radiology, Charite Medical School, Humboldt-Universitaet zu Berlin (Germany)

    2008-07-15

    Purpose: To prospectively analyze image quality and diagnostic accuracy of different reconstruction intervals of coronary angiography using multislice computed tomography (MSCT). Materials and methods: For each of 47 patients, 10 ECG-gated MSCT reconstructions were generated throughout the RR interval from 0 to 90%, resulting in altogether 470 datasets. These datasets were randomly analyzed for image quality and accuracy and compared with conventional angiography. Statistical comparison of intervals was performed using nonparametric analysis for repeated measurements to account for clustering of arteries within patients. Results: Image reconstruction intervals centered at 80, 70, and 40% of the RR interval resulted (in that order) in the best overall image quality for all four main coronary vessels. Eighty percent reconstructions also yielded the highest diagnostic accuracy of all intervals. The combination of the three best intervals (80, 70, and 40%) significantly reduced the nondiagnostic rate as compared with 80% alone (p = 0.005). However, the optimal reconstruction interval combination achieved significantly improved specificities and nondiagnostic rates (p < 0.05). The optimal combination consisted of 1.7 {+-} 0.9 reconstruction intervals on average. In approximately half of the patients (49%, 23/47) a single reconstruction was optimal. In 18 (38%), 3 (6%), and 3 (6%) patients one, two, and three additional reconstruction intervals were required, respectively, to achieve optimal quality. In 28% of the patients the optimal combination consisted of reconstructions other than the three best intervals (80, 70, and 40%). Conclusion: Multiple image reconstruction intervals are essential to ensure high image quality and accuracy of CT coronary angiography.

  6. An image correlation procedure for digitally reconstructed radiographs and electronic portal images

    International Nuclear Information System (INIS)

    Dong, Lei; Boyer, Arthur L.

    1995-01-01

    Purpose: To study a procedure that uses megavoltage digitally reconstructed radiographs (DRRs) calculated from patient's three-dimensional (3D) computed tomography (CT) data as a reference image for correlation with on-line electronic portal images (EPIs) to detect patient setup errors. Methods and Materials: Megavoltage DRRs were generated by ray tracing through a modified volumetric CT data set in which CT numbers were converted into linear attenuation coefficients for the therapeutic beam energy. The DRR transmission image was transformed to the grayscale window of the EPI by a histogram-matching technique. An alternative approach was to calibrate the transmission DRR using a measured response curve of the electronic portal imaging device (EPID). This forces the calculated transmission fluence values to be distributed in the same range as that of the EPID image. A cross-correlation technique was used to determine the degree of alignment of the patient anatomy found in the EPID image relative to the reference DRR. Results: Phantom studies demonstrated that the correlation procedure had a standard deviation of 0.5 mm and 0.5 deg. in aligning translational shifts and in-plane rotations. Systematic errors were found between a reference DRR and a reference EPID image. The automated grayscale image-correlation process was completed within 3 s on a workstation computer or 12 s on a PC. Conclusion: The alignment procedure allows the direct comparison of a patient's treatment portal designed with a 3D planning computer with a patient's on-line portal image acquired at the treatment unit. The image registration process is automated to the extent that it requires minimal user intervention, and it is fast and accurate enough for on-line clinical applications

  7. Maximum a posteriori reconstruction of the Patlak parametric image from sinograms in dynamic PET

    International Nuclear Information System (INIS)

    Wang Guobao; Fu Lin; Qi Jinyi

    2008-01-01

    Parametric imaging using the Patlak graphical method has been widely used to analyze dynamic PET data. Conventionally a Patlak parametric image is generated by reconstructing a sequence of dynamic images first and then performing Patlak graphical analysis on the time-activity curves pixel-by-pixel. However, because it is rather difficult to model the noise distribution in reconstructed images, the spatially variant noise correlation is simply ignored in the Patlak analysis, which leads to sub-optimal results. In this paper we present a Bayesian method for reconstructing Patlak parametric images directly from raw sinogram data by incorporating the Patlak plot model into the image reconstruction procedure. A preconditioned conjugate gradient algorithm is used to find the maximum a posteriori solution. The proposed direct method is statistically more efficient than the conventional indirect approach because the Poisson noise distribution in PET data can be accurately modeled in the direct reconstruction. The computation cost of the direct method is similar to reconstruction time of two dynamic frames. Therefore, when more than two dynamic frames are used in the Patlak analysis, the direct method is faster than the conventional indirect approach. We conduct computer simulations to validate the proposed direct method. Comparisons with the conventional indirect approach show that the proposed method results in a more accurate estimate of the parametric image. The proposed method has been applied to dynamic fully 3D PET data from a microPET scanner

  8. Magni: A Python Package for Compressive Sampling and Reconstruction of Atomic Force Microscopy Images

    DEFF Research Database (Denmark)

    Oxvig, Christian Schou; Pedersen, Patrick Steffen; Arildsen, Thomas

    2014-01-01

    Magni is an open source Python package that embraces compressed sensing and Atomic Force Microscopy (AFM) imaging techniques. It provides AFM-specific functionality for undersampling and reconstructing images from AFM equipment and thereby accelerating the acquisition of AFM images. Magni also pr...... as a convenient platform for researchers in compressed sensing aiming at obtaining a high degree of reproducibility of their research....

  9. A comparison of reconstruction methods for undersampled atomic force microscopy images

    International Nuclear Information System (INIS)

    Luo, Yufan; Andersson, Sean B

    2015-01-01

    Non-raster scanning and undersampling of atomic force microscopy (AFM) images is a technique for improving imaging rate and reducing the amount of tip–sample interaction needed to produce an image. Generation of the final image can be done using a variety of image processing techniques based on interpolation or optimization. The choice of reconstruction method has a large impact on the quality of the recovered image and the proper choice depends on the sample under study. In this work we compare interpolation through the use of inpainting algorithms with reconstruction based on optimization through the use of the basis pursuit algorithm commonly used for signal recovery in compressive sensing. Using four different sampling patterns found in non-raster AFM, namely row subsampling, spiral scanning, Lissajous scanning, and random scanning, we subsample data from existing images and compare reconstruction performance against the original image. The results illustrate that inpainting generally produces superior results when the image contains primarily low frequency content while basis pursuit is better when the images have mixed, but sparse, frequency content. Using support vector machines, we then classify images based on their frequency content and sparsity and, from this classification, develop a fast decision strategy to select a reconstruction algorithm to be used on subsampled data. The performance of the classification and decision test are demonstrated on test AFM images. (paper)

  10. DMSA SPECT imaging using oblique reconstruction in a paediatric population - benefits and technical considerations

    International Nuclear Information System (INIS)

    Parsons, G.; Ford, M.; Crisp, J.; Bernard, E.; Howman-Giles, R.

    1997-01-01

    Full text: DMSA renal scans are frequently requested for the diagnosis and follow-up of acute pyelonephritis and cortical scarring. This study was designed to:- 1. evaluate oblique reconstruction of DMSA SPECT over standard plane reconstruction and planar imaging; and 2. report on the technical aspects important in obtaining high quality DMSA SPECT, particularly in neonates. Over seven months, 210/231 (91 %) of DMSA scans were performed with SPECT on children from age nine days to 16 years, the median age being 2.5 years. 65 patients (31 %) were under one year and 39 (18%) were under six months. Planar and SPECT imaging with standard plane reconstruction and oblique reorientation was performed on the Siemens triple-headed gamma camera. High quality SPECT images were obtained on the smallest babies using a paediatric palette, and were of comparable quality to those of older children. At the time of reporting, the nuclear medicine physician assessed the diagnostic value of the three types of date presented: (1) planar images; (2) standard plane SPECT reconstruction; and (3) oblique SPECT reconstruction. Cortical defects were identified separately for upper, middle and lower poles. Three physicians concluded that high quality SPECT is superior to planar images when assessing the renal cortex. In addition, oblique reorientation is superior to standard reconstruction, particularly at the upper and lower poles. SPECT is now performed routinely on patients of all ages, and the oblique sagittal and coronal reorientation is now used in place of the standard reconstruction

  11. GREIT: a unified approach to 2D linear EIT reconstruction of lung images.

    Science.gov (United States)

    Adler, Andy; Arnold, John H; Bayford, Richard; Borsic, Andrea; Brown, Brian; Dixon, Paul; Faes, Theo J C; Frerichs, Inéz; Gagnon, Hervé; Gärber, Yvo; Grychtol, Bartłomiej; Hahn, Günter; Lionheart, William R B; Malik, Anjum; Patterson, Robert P; Stocks, Janet; Tizzard, Andrew; Weiler, Norbert; Wolf, Gerhard K

    2009-06-01

    Electrical impedance tomography (EIT) is an attractive method for clinically monitoring patients during mechanical ventilation, because it can provide a non-invasive continuous image of pulmonary impedance which indicates the distribution of ventilation. However, most clinical and physiological research in lung EIT is done using older and proprietary algorithms; this is an obstacle to interpretation of EIT images because the reconstructed images are not well characterized. To address this issue, we develop a consensus linear reconstruction algorithm for lung EIT, called GREIT (Graz consensus Reconstruction algorithm for EIT). This paper describes the unified approach to linear image reconstruction developed for GREIT. The framework for the linear reconstruction algorithm consists of (1) detailed finite element models of a representative adult and neonatal thorax, (2) consensus on the performance figures of merit for EIT image reconstruction and (3) a systematic approach to optimize a linear reconstruction matrix to desired performance measures. Consensus figures of merit, in order of importance, are (a) uniform amplitude response, (b) small and uniform position error, (c) small ringing artefacts, (d) uniform resolution, (e) limited shape deformation and (f) high resolution. Such figures of merit must be attained while maintaining small noise amplification and small sensitivity to electrode and boundary movement. This approach represents the consensus of a large and representative group of experts in EIT algorithm design and clinical applications for pulmonary monitoring. All software and data to implement and test the algorithm have been made available under an open source license which allows free research and commercial use.

  12. GREIT: a unified approach to 2D linear EIT reconstruction of lung images

    International Nuclear Information System (INIS)

    Adler, Andy; Arnold, John H; Bayford, Richard; Tizzard, Andrew; Borsic, Andrea; Brown, Brian; Dixon, Paul; Faes, Theo J C; Frerichs, Inéz; Weiler, Norbert; Gagnon, Hervé; Gärber, Yvo; Grychtol, Bartłomiej; Hahn, Günter; Lionheart, William R B; Malik, Anjum; Patterson, Robert P; Stocks, Janet; Wolf, Gerhard K

    2009-01-01

    Electrical impedance tomography (EIT) is an attractive method for clinically monitoring patients during mechanical ventilation, because it can provide a non-invasive continuous image of pulmonary impedance which indicates the distribution of ventilation. However, most clinical and physiological research in lung EIT is done using older and proprietary algorithms; this is an obstacle to interpretation of EIT images because the reconstructed images are not well characterized. To address this issue, we develop a consensus linear reconstruction algorithm for lung EIT, called GREIT (Graz consensus Reconstruction algorithm for EIT). This paper describes the unified approach to linear image reconstruction developed for GREIT. The framework for the linear reconstruction algorithm consists of (1) detailed finite element models of a representative adult and neonatal thorax, (2) consensus on the performance figures of merit for EIT image reconstruction and (3) a systematic approach to optimize a linear reconstruction matrix to desired performance measures. Consensus figures of merit, in order of importance, are (a) uniform amplitude response, (b) small and uniform position error, (c) small ringing artefacts, (d) uniform resolution, (e) limited shape deformation and (f) high resolution. Such figures of merit must be attained while maintaining small noise amplification and small sensitivity to electrode and boundary movement. This approach represents the consensus of a large and representative group of experts in EIT algorithm design and clinical applications for pulmonary monitoring. All software and data to implement and test the algorithm have been made available under an open source license which allows free research and commercial use

  13. Optimization of SPECT-CT Hybrid Imaging Using Iterative Image Reconstruction for Low-Dose CT: A Phantom Study.

    Directory of Open Access Journals (Sweden)

    Oliver S Grosser

    Full Text Available Hybrid imaging combines nuclear medicine imaging such as single photon emission computed tomography (SPECT or positron emission tomography (PET with computed tomography (CT. Through this hybrid design, scanned patients accumulate radiation exposure from both applications. Imaging modalities have been the subject of long-term optimization efforts, focusing on diagnostic applications. It was the aim of this study to investigate the influence of an iterative CT image reconstruction algorithm (ASIR on the image quality of the low-dose CT images.Examinations were performed with a SPECT-CT scanner with standardized CT and SPECT-phantom geometries and CT protocols with systematically reduced X-ray tube currents. Analyses included image quality with respect to photon flux. Results were compared to the standard FBP reconstructed images. The general impact of the CT-based attenuation maps used during SPECT reconstruction was examined for two SPECT phantoms. Using ASIR for image reconstructions, image noise was reduced compared to FBP reconstructions for the same X-ray tube current. The Hounsfield unit (HU values reconstructed by ASIR were correlated to the FBP HU values(R2 ≥ 0.88 and the contrast-to-noise ratio (CNR was improved by ASIR. However, for a phantom with increased attenuation, the HU values shifted for low X-ray tube currents I ≤ 60 mA (p ≤ 0.04. In addition, the shift of the HU values was observed within the attenuation corrected SPECT images for very low X-ray tube currents (I ≤ 20 mA, p ≤ 0.001.In general, the decrease in X-ray tube current up to 30 mA in combination with ASIR led to a reduction of CT-related radiation exposure without a significant decrease in image quality.

  14. Adaptive tight frame based medical image reconstruction: a proof-of-concept study for computed tomography

    International Nuclear Information System (INIS)

    Zhou, Weifeng; Cai, Jian-Feng; Gao, Hao

    2013-01-01

    A popular approach for medical image reconstruction has been through the sparsity regularization, assuming the targeted image can be well approximated by sparse coefficients under some properly designed system. The wavelet tight frame is such a widely used system due to its capability for sparsely approximating piecewise-smooth functions, such as medical images. However, using a fixed system may not always be optimal for reconstructing a variety of diversified images. Recently, the method based on the adaptive over-complete dictionary that is specific to structures of the targeted images has demonstrated its superiority for image processing. This work is to develop the adaptive wavelet tight frame method image reconstruction. The proposed scheme first constructs the adaptive wavelet tight frame that is task specific, and then reconstructs the image of interest by solving an l 1 -regularized minimization problem using the constructed adaptive tight frame system. The proof-of-concept study is performed for computed tomography (CT), and the simulation results suggest that the adaptive tight frame method improves the reconstructed CT image quality from the traditional tight frame method. (paper)

  15. Edge-oriented dual-dictionary guided enrichment (EDGE) for MRI-CT image reconstruction.

    Science.gov (United States)

    Li, Liang; Wang, Bigong; Wang, Ge

    2016-01-01

    In this paper, we formulate the joint/simultaneous X-ray CT and MRI image reconstruction. In particular, a novel algorithm is proposed for MRI image reconstruction from highly under-sampled MRI data and CT images. It consists of two steps. First, a training dataset is generated from a series of well-registered MRI and CT images on the same patients. Then, an initial MRI image of a patient can be reconstructed via edge-oriented dual-dictionary guided enrichment (EDGE) based on the training dataset and a CT image of the patient. Second, an MRI image is reconstructed using the dictionary learning (DL) algorithm from highly under-sampled k-space data and the initial MRI image. Our algorithm can establish a one-to-one correspondence between the two imaging modalities, and obtain a good initial MRI estimation. Both noise-free and noisy simulation studies were performed to evaluate and validate the proposed algorithm. The results with different under-sampling factors show that the proposed algorithm performed significantly better than those reconstructed using the DL algorithm from MRI data alone.

  16. A singular K-space model for fast reconstruction of magnetic resonance images from undersampled data.

    Science.gov (United States)

    Luo, Jianhua; Mou, Zhiying; Qin, Binjie; Li, Wanqing; Ogunbona, Philip; Robini, Marc C; Zhu, Yuemin

    2017-12-09

    Reconstructing magnetic resonance images from undersampled k-space data is a challenging problem. This paper introduces a novel method of image reconstruction from undersampled k-space data based on the concept of singularizing operators and a novel singular k-space model. Exploring the sparsity of an image in the k-space, the singular k-space model (SKM) is proposed in terms of the k-space functions of a singularizing operator. The singularizing operator is constructed by combining basic difference operators. An algorithm is developed to reliably estimate the model parameters from undersampled k-space data. The estimated parameters are then used to recover the missing k-space data through the model, subsequently achieving high-quality reconstruction of the image using inverse Fourier transform. Experiments on physical phantom and real brain MR images have shown that the proposed SKM method constantly outperforms the popular total variation (TV) and the classical zero-filling (ZF) methods regardless of the undersampling rates, the noise levels, and the image structures. For the same objective quality of the reconstructed images, the proposed method requires much less k-space data than the TV method. The SKM method is an effective method for fast MRI reconstruction from the undersampled k-space data. Graphical abstract Two Real Images and their sparsified images by singularizing operator.

  17. Image Reconstruction for Diffuse Optical Tomography Based on Radiative Transfer Equation

    Directory of Open Access Journals (Sweden)

    Bo Bi

    2015-01-01

    L2 regularization. Results also show the competitive performance of the split Bregman algorithm for the DOT image reconstruction with sparsity regularization compared with other existing L1 algorithms.

  18. A Combined First and Second Order Variational Approach for Image Reconstruction

    KAUST Repository

    Papafitsoros, K.; Schö nlieb, C. B.

    2013-01-01

    the creation of undesirable artifacts and blocky-like structures in the reconstructed images-a known disadvantage of the ROF model-while being simple and efficiently numerically solvable. ©Springer Science+Business Media New York 2013.

  19. A two-step Hilbert transform method for 2D image reconstruction

    International Nuclear Information System (INIS)

    Noo, Frederic; Clackdoyle, Rolf; Pack, Jed D

    2004-01-01

    The paper describes a new accurate two-dimensional (2D) image reconstruction method consisting of two steps. In the first step, the backprojected image is formed after taking the derivative of the parallel projection data. In the second step, a Hilbert filtering is applied along certain lines in the differentiated backprojection (DBP) image. Formulae for performing the DBP step in fan-beam geometry are also presented. The advantage of this two-step Hilbert transform approach is that in certain situations, regions of interest (ROIs) can be reconstructed from truncated projection data. Simulation results are presented that illustrate very similar reconstructed image quality using the new method compared to standard filtered backprojection, and that show the capability to correctly handle truncated projections. In particular, a simulation is presented of a wide patient whose projections are truncated laterally yet for which highly accurate ROI reconstruction is obtained

  20. Image Reconstruction Based on Homotopy Perturbation Inversion Method for Electrical Impedance Tomography

    Directory of Open Access Journals (Sweden)

    Jing Wang

    2013-01-01

    Full Text Available The image reconstruction for electrical impedance tomography (EIT mathematically is a typed nonlinear ill-posed inverse problem. In this paper, a novel iteration regularization scheme based on the homotopy perturbation technique, namely, homotopy perturbation inversion method, is applied to investigate the EIT image reconstruction problem. To verify the feasibility and effectiveness, simulations of image reconstruction have been performed in terms of considering different locations, sizes, and numbers of the inclusions, as well as robustness to data noise. Numerical results indicate that this method can overcome the numerical instability and is robust to data noise in the EIT image reconstruction. Moreover, compared with the classical Landweber iteration method, our approach improves the convergence rate. The results are promising.

  1. FIRST: Fast Iterative Reconstruction Software for (PET) tomography

    International Nuclear Information System (INIS)

    Herraiz, J L; Espana, S; Vaquero, J J; Desco, M; UdIas, J M

    2006-01-01

    Small animal PET scanners require high spatial resolution and good sensitivity. To reconstruct high-resolution images in 3D-PET, iterative methods, such as OSEM, are superior to analytical reconstruction algorithms, although their high computational cost is still a serious drawback. The higher performance of modern computers could make iterative image reconstruction fast enough to be viable, provided we are able to deal with the large number of probability coefficients for the system response matrix in high-resolution PET scanners, which is a difficult task that prevents the algorithms from reaching peak computing performance. Considering all possible axial and in-plane symmetries, as well as certain quasi-symmetries, we have been able to reduce the memory requirements to store the system response matrix (SRM) well below 1 GB, which allows us to keep the whole response matrix of the system inside RAM of ordinary industry-standard computers, so that the reconstruction algorithm can achieve near peak performance. The elements of the SRM are stored as cubic spline profiles and matched to voxel size during reconstruction. In this way, the advantages of 'on-the-fly' calculation and of fully stored SRM are combined. The on-the-fly part of the calculation (matching the profile functions to voxel size) of the SRM accounts for 10-30% of the reconstruction time, depending on the number of voxels chosen. We tested our approach with real data from a commercial small animal PET scanner. The results (image quality and reconstruction time) show that the proposed technique is a feasible solution

  2. FIRST: Fast Iterative Reconstruction Software for (PET) tomography

    Energy Technology Data Exchange (ETDEWEB)

    Herraiz, J L [Dpto. Fisica Atomica, Molecular y Nuclear, Universidad Complutense de Madrid (Spain); Espana, S [Dpto. Fisica Atomica, Molecular y Nuclear, Universidad Complutense de Madrid (Spain); Vaquero, J J [Unidad de Medicina y CirugIa Experimental, Hospital GU Gregorio Maranon, Madrid (Spain); Desco, M [Unidad de Medicina y CirugIa Experimental, Hospital GU Gregorio Maranon, Madrid (Spain); UdIas, J M [Dpto. Fisica Atomica, Molecular y Nuclear, Universidad Complutense de Madrid (Spain)

    2006-09-21

    Small animal PET scanners require high spatial resolution and good sensitivity. To reconstruct high-resolution images in 3D-PET, iterative methods, such as OSEM, are superior to analytical reconstruction algorithms, although their high computational cost is still a serious drawback. The higher performance of modern computers could make iterative image reconstruction fast enough to be viable, provided we are able to deal with the large number of probability coefficients for the system response matrix in high-resolution PET scanners, which is a difficult task that prevents the algorithms from reaching peak computing performance. Considering all possible axial and in-plane symmetries, as well as certain quasi-symmetries, we have been able to reduce the memory requirements to store the system response matrix (SRM) well below 1 GB, which allows us to keep the whole response matrix of the system inside RAM of ordinary industry-standard computers, so that the reconstruction algorithm can achieve near peak performance. The elements of the SRM are stored as cubic spline profiles and matched to voxel size during reconstruction. In this way, the advantages of 'on-the-fly' calculation and of fully stored SRM are combined. The on-the-fly part of the calculation (matching the profile functions to voxel size) of the SRM accounts for 10-30% of the reconstruction time, depending on the number of voxels chosen. We tested our approach with real data from a commercial small animal PET scanner. The results (image quality and reconstruction time) show that the proposed technique is a feasible solution.

  3. Accelerated gradient methods for total-variation-based CT image reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Joergensen, Jakob H.; Hansen, Per Christian [Technical Univ. of Denmark, Lyngby (Denmark). Dept. of Informatics and Mathematical Modeling; Jensen, Tobias L.; Jensen, Soeren H. [Aalborg Univ. (Denmark). Dept. of Electronic Systems; Sidky, Emil Y.; Pan, Xiaochuan [Chicago Univ., Chicago, IL (United States). Dept. of Radiology

    2011-07-01

    Total-variation (TV)-based CT image reconstruction has shown experimentally to be capable of producing accurate reconstructions from sparse-view data. In particular TV-based reconstruction is well suited for images with piecewise nearly constant regions. Computationally, however, TV-based reconstruction is demanding, especially for 3D imaging, and the