WorldWideScience

Sample records for organization origins development

  1. Mitochondrial DNA, chloroplast DNA and the origins of development in eukaryotic organisms

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    Bendich Arnold J

    2010-06-01

    Full Text Available Abstract Background Several proposals have been made to explain the rise of multicellular life forms. An internal environment can be created and controlled, germ cells can be protected in novel structures, and increased organismal size allows a "division of labor" among cell types. These proposals describe advantages of multicellular versus unicellular organisms at levels of organization at or above the individual cell. I focus on a subsequent phase of evolution, when multicellular organisms initiated the process of development that later became the more complex embryonic development found in animals and plants. The advantage here is realized at the level of the mitochondrion and chloroplast. Hypothesis The extreme instability of DNA in mitochondria and chloroplasts has not been widely appreciated even though it was first reported four decades ago. Here, I show that the evolutionary success of multicellular animals and plants can be traced to the protection of organellar DNA. Three stages are envisioned. Sequestration allowed mitochondria and chloroplasts to be placed in "quiet" germ line cells so that their DNA is not exposed to the oxidative stress produced by these organelles in "active" somatic cells. This advantage then provided Opportunity, a period of time during which novel processes arose for signaling within and between cells and (in animals for cell-cell recognition molecules to evolve. Development then led to the enormous diversity of animals and plants. Implications The potency of a somatic stem cell is its potential to generate cell types other than itself, and this is a systems property. One of the biochemical properties required for stemness to emerge from a population of cells might be the metabolic quiescence that protects organellar DNA from oxidative stress. Reviewers This article was reviewed by John Logsdon, Arcady Mushegian, and Patrick Forterre.

  2. ORIGINS AND DEVELOPMENT OF THE ORGANIZED CRIME IN LATIN AMERICA (1916-2013

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    MIGUEL ORTIZ SARKIS

    2017-12-01

    Full Text Available The organized crime manifests in different forms and varies according to the characteristics present in each of the Latin American societies that allowed its emergence. In the Mexican case, the collusion between the drug trafficking and the political power emerges after the Mexican Revolution at the beginning of the 21st Century. Therefore, this article propounds that the problem of the organized crime in Latin American has a structural character and, thus, is irremediable in the short term; moreover, if the use of military force is one of the most important instrument to fight it.

  3. Historical Development of Origins Research

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    Lazcano, Antonio

    2010-01-01

    Following the publication of the Origin of Species in 1859, many naturalists adopted the idea that living organisms were the historical outcome of gradual transformation of lifeless matter. These views soon merged with the developments of biochemistry and cell biology and led to proposals in which the origin of protoplasm was equated with the origin of life. The heterotrophic origin of life proposed by Oparin and Haldane in the 1920s was part of this tradition, which Oparin enriched by transforming the discussion of the emergence of the first cells into a workable multidisciplinary research program. On the other hand, the scientific trend toward understanding biological phenomena at the molecular level led authors like Troland, Muller, and others to propose that single molecules or viruses represented primordial living systems. The contrast between these opposing views on the origin of life represents not only contrasting views of the nature of life itself, but also major ideological discussions that reached a surprising intensity in the years following Stanley Miller’s seminal result which showed the ease with which organic compounds of biochemical significance could be synthesized under putative primitive conditions. In fact, during the years following the Miller experiment, attempts to understand the origin of life were strongly influenced by research on DNA replication and protein biosynthesis, and, in socio-political terms, by the atmosphere created by Cold War tensions. The catalytic versatility of RNA molecules clearly merits a critical reappraisal of Muller’s viewpoint. However, the discovery of ribozymes does not imply that autocatalytic nucleic acid molecules ready to be used as primordial genes were floating in the primitive oceans, or that the RNA world emerged completely assembled from simple precursors present in the prebiotic soup. The evidence supporting the presence of a wide range of organic molecules on the primitive Earth, including membrane

  4. [Overview of organic agriculture development.

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    Liu, Xiao Mei; Yu, Hong Jun; Li, Qiang; Jiang, Wei Jie

    2016-04-22

    This paper introduced the concepts of organic agriculture as defined by different international organizations, origin and theoretical development of organic agriculture, as well as its developing trajectory in China (i.e. a late start followed by rapid growth compared to developed countries). The differences between domestic and international organic agriculture were illustrated by scale, crop types, production standards, inputs and planting techniques. Constraints limiting improvements to organic agriculture in aspects of standards, technology, marketing, certification, environmental pollution, enterprise reputation, and national policies were discussed. Future directions and strategies for developing healthy organic agriculture in China were provided.

  5. Organic Minerals in the Origin of Life

    Science.gov (United States)

    Benner, S.; Biondi, E.; Kim, H. J.

    2017-12-01

    Models for the origin of life are plagued by fundamental problems that, due to their difficulty, are called "paradoxes". One of these, known to anyone who has ever worked in a kitchen, is that organics, when given energy and left to itself, does not generate life. Rather, organics devolve to give tarry mixtures that become increasingly complex and increasingly less likely to support life (like asphalt). However, even if those mixtures escape devolution to create something useful for Darwinism, like building blocks for RNA, the water in which they must work is corrosive, leading to their destruction. Even if RNA is created, it is itself easily degraded. One current trend to manage those paradoxes turns to minerals in environments on early Earth. Inorganic minerals containing borate have now been shown to prevent the destruction of ribose (the R in RNA) and other carbohydrates essential for early Earth. Evaporite desert basins supplied with aqueous runoff from tourmaline-containing basalts are ideal environments for forming borate minerals, especially if they are made alkaline by serpentinizing peridotite. In the evaporite environments, drying cycles mitigate the destructive capability of water. Further, we have shown that phosphate is segregated from calcium (avoiding formation of relatively unreacted apatites) if magnesium and borate are present. Further, a common magnesium borophosphate (luneburgite) not only makes phosphate available for prebiotic synthesis, but selectively phosphorylates RNA building blocks as it releases borate to stabilize them against further degradation. Finally, a variety of minerals bind and stabilize RNA itself. Research in this area has also discovered organic minerals that might have been relevant to the origins of life on Earth. Such minerals are scarce on Earth today, since they are easily consumed by microbial communities. However, on a prebiotic Earth, organic minerals could have stored organic species as intermediates towards our

  6. Origin and development of comets

    International Nuclear Information System (INIS)

    Kresak, L.

    1989-01-01

    The comets are the most primitive and probably also the oldest members of the solar system. Comet cores are brittle bodies of an irregular shape and of a size of 1 to 10 km whose main component is ice. Around 130 comets move along short-period paths whose aphelia are concentrated in the area of Jupiter. They are in the last stage of development. About 20 comets have periods of 20 to 200 years and feature higher motion stability. Roughly 180 comets have elliptical orbits of a period exceeding 200 years, 200 comets have parabolic and 120 comets have hyperbolic orbits. The most distant comets form the Oort cloud around the solar system consisting of about one billion comets. Comets originated roughly 4.6 thousand million years ago together with planets, probably inside the Oort cloud. (M.D.). 11 figs

  7. Documenting costs and yield of crops of organic origin

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    J.P. Melnychuk

    2016-06-01

    Full Text Available The article focuses on the study of primary cost accounting and output of organic crop production. The article has also agreed the key issues that ensure in the primary accounting of organic crop production. For the survey we have used such general scientific methods as induction and deduction, dialectic, historical and systematic methods and some specific methods of accounting which include documentation, inventory, assessment, calculation, accounting records, double entry, balance sheet and financial statements. . As for the documentation of costs and yield of crops of organic origin, it should be noted that documentation is an important method of accounting as it’s the basis of initial observation of commercial operations and it’s a prerequisite for their reflection in accounting. The article has highlighted the features of documenting the posting of production costs and crop production of organic origin, and has also studied the order of registration of land in the operating lease for the production of organic products. The author submits the suggestions for improvement of documenting costs and yields of organic crop production in order to develop reliable information about the costs of production and the grown crop of organic origin for management decision-making.

  8. Energy sources, self-organization, and the origin of life.

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    Boiteau, Laurent; Pascal, Robert

    2011-02-01

    The emergence and early developments of life are considered from the point of view that contingent events that inevitably marked evolution were accompanied by deterministic driving forces governing the selection between different alternatives. Accordingly, potential energy sources are considered for their propensity to induce self-organization within the scope of the chemical approach to the origin of life. Requirements in terms of quality of energy locate thermal or photochemical activation in the atmosphere as highly likely processes for the formation of activated low-molecular weight organic compounds prone to induce biomolecular self-organization through their ability to deliver quanta of energy matching the needs of early biochemical pathways or the reproduction of self-replicating entities. These lines of reasoning suggest the existence of a direct connection between the free energy content of intermediates of early pathways and the quanta of energy delivered by available sources of energy.

  9. Origin, development, and evolution of butterfly eyespots.

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    Monteiro, Antónia

    2015-01-07

    This article reviews the latest developments in our understanding of the origin, development, and evolution of nymphalid butterfly eyespots. Recent contributions to this field include insights into the evolutionary and developmental origin of eyespots and their ancestral deployment on the wing, the evolution of eyespot number and eyespot sexual dimorphism, and the identification of genes affecting eyespot development and black pigmentation. I also compare features of old and more recently proposed models of eyespot development and propose a schematic for the genetic regulatory architecture of eyespots. Using this schematic I propose two hypotheses for why we observe limits to morphological diversity across these serially homologous traits.

  10. Accounting organizing development tendencies

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    G.I. Lyakhovich

    2017-12-01

    Full Text Available The development of accounting takes place under the influence of many factors. The study pays special attention to the impact of technological determinants on the process of organizing accountin. The carried-out analysis of scientists’ works allowed to determine the principal tendencies in the development of accounting organizing; these tendencies were expanded taking into account the development of technologies and innovations. It was found out the particular element, which undergo changes in the organization of accounting and the factors that prevent their further development for every tendency (the use of cloud technologies; a wide use of expert systems; a social media strategy in accounting; mobility among accounting personnel; outsourcing of accounting services, Internet things. The paper substantiates the shifts in functional duties of an accountant (the exclusion of data recording and intensification of analytical functions as a result of application of modern information and computer technologies. It was established that the amounts of accountants’ work with primary instruments will be reduced taking into account the possibilities of automatic preparation of such documents. The author substantiates the importance of the good knowledge in the field of information technologies while training accountants.

  11. Adventist Education: origin, development and expasion

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    Patrick Vieira Ferreira

    2018-03-01

    Full Text Available This article aimed to present a brief historical report of the origin, development and consolidation of the Adventist Education Network. Thus, it will be possible to know about its emergence, philosophy of education and the genesis of this confessional network operating in the Brazilian educational scenario for more than a century. The research method includes bibliographical analysis of the main theoreticians of the Brazilian history of education and rescues facts cited by Adventist historians. The research situated the Adventist Education Network in the Brazilian historical context and identified the Seventh-day Adventists as a religious group and as agents in the field of school education.

  12. Origin of Negative Capacitance in Bipolar Organic Diodes

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    Niu, Quan; Crǎciun, N. Irina; Wetzelaer, Gert-Jan A. H.; Blom, Paul W. M.

    2018-03-01

    Negative differential capacitance (NC) occurring at low frequencies in organic light-emitting diodes (OLEDs) is a poorly understood phenomenon. We study the origin of the NC effect by systematically varying the number of electron traps in OLEDs based on the polymeric semiconductor poly(p -phenylene vinylene). Increasing the electron trap density enhances the NC effect. The magnitude and observed decrease of the relaxation time is consistent with the (inverse) rate of trap-assisted recombination. The absence of NC in a nearly trap-free light-emitting diode unambiguously shows that trap-assisted recombination is the responsible mechanism for the negative contribution to the capacitance in bipolar organic diodes. Our results reveal that the NC effect can be exploited to quantitatively determine the number of traps in organic semiconductors in a nondestructive fashion.

  13. a Study of the Origin of Atmospheric Organic Aerosols

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    Hildemann, Lynn Mary

    1990-01-01

    predictions and ambient concentrations that could be due to atmospheric chemical reaction are discussed. An upper limit on the amount of secondary organic aerosol present is estimated based on the difference between the acidic organic aerosol present in ambient samples versus that due to primary emissions as computed by the model. Finally, several hypotheses concerning the origin of the organic aerosol are proposed.

  14. Exploring the Origins of Deuterium Enrichments in Solar Nebular Organics

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    Cleeves, L. Ilsedore; Bergin, Edwin A.; O'D. Alexander, Conel M.; Du, Fujun; Graninger, Dawn; Öberg, Karin I.; Harries, Tim J.

    2016-03-01

    Deuterium-to-hydrogen (D/H) enrichments in molecular species provide clues about their original formation environment. The organic materials in primitive solar system bodies generally have higher D/H ratios and show greater D/H variation when compared to D/H in solar system water. We propose this difference arises at least in part due to (1) the availability of additional chemical fractionation pathways for organics beyond that for water, and (2) the higher volatility of key carbon reservoirs compared to oxygen. We test this hypothesis using detailed disk models, including a sophisticated, new disk ionization treatment with a low cosmic-ray ionization rate, and find that disk chemistry leads to higher deuterium enrichment in organics compared to water, helped especially by fractionation via the precursors CH2D+/CH3+. We also find that the D/H ratio in individual species varies significantly depending on their particular formation pathways. For example, from ˜20-40 au, CH4 can reach {{D}}/{{H}}˜ 2× {10}-3, while D/H in CH3OH remains locally unaltered. Finally, while the global organic D/H in our models can reproduce intermediately elevated D/H in the bulk hydrocarbon reservoir, our models are unable to reproduce the most deuterium-enriched organic materials in the solar system, and thus our model requires some inheritance from the cold interstellar medium from which the Sun formed.

  15. Organizers in Development.

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    Anderson, Claire; Stern, Claudio D

    2016-01-01

    An "organizer" is formally defined as a region, or group of cells in an embryo that can both induce (change the fate) and pattern (generate an organized set of structures) adjacent embryonic cells. To date, about four such regions have been demonstrated: the primary or Spemann organizer (Hensen's node in amniotes), the notochord, the zone of polarizing activity of the limb bud, and the mid-hindbrain boundary. Here we review the evidence for these and compare them with a few other regions which have been proposed to represent other organizers and we speculate on why so few such regions have been discovered. © 2016 Elsevier Inc. All rights reserved.

  16. Mechanical origins of rightward torsion in early chick brain development

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    Chen, Zi; Guo, Qiaohang; Dai, Eric; Taber, Larry

    2015-03-01

    During early development, the neural tube of the chick embryo undergoes a combination of progressive ventral bending and rightward torsion. This torsional deformation is one of the major organ-level left-right asymmetry events in development. Previous studies suggested that bending is mainly due to differential growth, however, the mechanism for torsion remains poorly understood. Since the heart almost always loops rightwards that the brain twists, researchers have speculated that heart looping affects the direction of brain torsion. However, direct evidence is lacking, nor is the mechanical origin of such torsion understood. In our study, experimental perturbations show that the bending and torsional deformations in the brain are coupled and that the vitelline membrane applies an external load necessary for torsion to occur. Moreover, the asymmetry of the looping heart gives rise to the chirality of the twisted brain. A computational model and a 3D printed physical model are employed to help interpret these findings. Our work clarifies the mechanical origins of brain torsion and the associated left-right asymmetry, and further reveals that the asymmetric development in one organ can induce the asymmetry of another developing organ through mechanics, reminiscent of D'Arcy Thompson's view of biological form as ``diagram of forces''. Z.C. is supported by the Society in Science - Branco Weiss fellowship, administered by ETH Zurich. L.A.T acknowledges the support from NIH Grants R01 GM075200 and R01 NS070918.

  17. Origins and bioavailability of dissolved organic matter in groundwater

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    Shen, Yuan; Chapelle, Francis H.; Strom, Eric W.; Benner, Ronald

    2015-01-01

    Dissolved organic matter (DOM) in groundwater influences water quality and fuels microbial metabolism, but its origins, bioavailability and chemical composition are poorly understood. The origins and concentrations of dissolved organic carbon (DOC) and bioavailable DOM were monitored during a long-term (2-year) study of groundwater in a fractured-rock aquifer in the Carolina slate belt. Surface precipitation was significantly correlated with groundwater concentrations of DOC, bioavailable DOM and chromophoric DOM, indicating strong hydrological connections between surface and ground waters. The physicochemical and biological processes shaping the concentrations and compositions of DOM during its passage through the soil column to the saturated zone are conceptualized in the regional chromatography model. The model provides a framework for linking hydrology with the processes affecting the transformation, remineralization and microbial production of DOM during passage through the soil column. Lignin-derived phenols were relatively depleted in groundwater DOM indicating substantial removal in the unsaturated zone, and optical properties of chromophoric DOM indicated lower molecular weight DOM in groundwater relative to surface water. The prevalence of glycine, γ-aminobutyric acid, and d-enantiomers of amino acids indicated the DOM was highly diagenetically altered. Bioassay experiments were used to establish DOC-normalized yields of amino acids as molecular indicators of DOM bioavailability in groundwater. A relatively small fraction (8 ± 4 %) of DOC in groundwater was bioavailable. The relatively high yields of specific d-enantiomers of amino acids indicated a substantial fraction (15–34 %) of groundwater DOC was of bacterial origin.

  18. Levels of biological organization and the origin of novelty.

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    Hall, Brian K; Kerney, Ryan

    2012-09-01

    The concept of novelty in evolutionary biology pertains to multiple tiers of biological organization from behavioral and morphological changes to changes at the molecular level. Identifying novel features requires assessments of similarity (homology and homoplasy) of relationships (phylogenetic history) and of shared developmental and genetic pathways or networks. After a brief discussion of how novelty is used in recent literature, we discuss whether the evolutionary approach to homology and homoplasy initially formulated by Lankester in the 19th century informs our understanding of novelty today. We then discuss six examples of morphological features described in the recent literature as novelties, and assess the basis upon which they are regarded as novel. The six are: origin of the turtle shell, transition from fish fins to tetrapod limbs, origination of the neural crest and neural crest cells, cement glands in frogs and casquettes in fish, whale bone-eating tubeworms, and the digestion of plant proteins by nematodes. The article concludes with a discussion of means of acquiring novel genetic information that can account for novelty recognized at higher levels. These are co-options of existing genetic circuitry, gene duplication followed by neofunctionalization, gene rearrangements through mobile genetic elements, and lateral gene transfer. We conclude that on the molecular level only the latter category provides novel genetic information, in that there is no homologous precursor. However, novel phenotypes can be generated through both neofunctionalization and gene rearrangements. Therefore, assigning phenotypic or genotypic "novelty" is contingent on the level of biological organization addressed. Copyright © 2011 Wiley Periodicals, Inc.

  19. College and Career Development Organizer

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    National High School Center, 2012

    2012-01-01

    The National High School Center has created a college and career development organizer to synthesize and organize an increasingly complicated and crowded field of college and career readiness initiatives. The organizer, composed of three strands, can be used to map the efforts of state education agencies (SEAs) and local education agencies (LEAs)…

  20. Trends in organization development

    NARCIS (Netherlands)

    Allegro, J.T.; Steensma, H.O.; Allegro, J.T.; Steensma, H.O.

    1985-01-01

    Organisation Development (OD) is an extraordinarly complex phenomenon of human society in which in the last few years there have been some interesting developments. Without making any claim to completeness the following topics would seem to have been a focus of interest in recent research on the

  1. Glossary of Organization Development Terminology.

    Science.gov (United States)

    Krepner-Tregoe and Associates, Inc., Princeton, NJ.

    Ranging from Action Sequence to Zero Defects, this Kepner-Tregoe glossary defines 194 terms (including some specifically Kepner-Tregoe) relevant to the fields of management development, organization development, and industrial training. (LY)

  2. How important is country-of-origin for organic food consumers?

    DEFF Research Database (Denmark)

    Thøgersen, John; Pedersen, Susanne; Paternoga, Maria

    2017-01-01

    preferences and choices. In general, COO seems to lose impact when other quality cues are salient. This suggests a lower impact of COO for organic than for conventional food products. However, there is still no research on the possible impact of organic labelling in categories where products from a foreign......Purpose – The purpose of this paper is to review the literature on the country-of-origin (COO) effect in the context of organic food and develop suggestions for further research in this area. Research has investigated COO effects and consumer responses to organic food, but there is little research...... on the combination of the two. Design/methodology/approach – A narrative review of two research streams and their intersection, forming the basis for the development of a research agenda. Findings – There are few studies analysing the possible interaction between the effects of organic and COO on consumers’ food...

  3. Health Physics Society: origins and development

    International Nuclear Information System (INIS)

    Kathren, R.L.

    1978-08-01

    Events leading up to the birth of the Health Physics Society in June, 1955, are reviewed. Membership requirements, chapters, and sections are discussed. An international organization, International Radiation Protection Association (IRPA), founded in 1963, was the outgrowth of the Health Physics Society. Other events in the history of the organization, such as the initiation of publishing of a society journal in 1957, the employment of the first Executive Secretary in 1965, and the establishment of awards, are reviewed. The two appendixes include lists of the officers of the society and award recipients

  4. The Development of Organized Rehearsal

    Science.gov (United States)

    Weist, Richard M.; Crawford, Jack

    1977-01-01

    In a study of development of organization strategies in rehearsal processes, children in the first, third, and fifth grades were exposed to a memory task which involved multiple overt rehearsal and recall phases. (SB)

  5. Origin of poor doping efficiency in solution processed organic semiconductors.

    Science.gov (United States)

    Jha, Ajay; Duan, Hong-Guang; Tiwari, Vandana; Thorwart, Michael; Miller, R J Dwayne

    2018-05-21

    Doping is an extremely important process where intentional insertion of impurities in semiconductors controls their electronic properties. In organic semiconductors, one of the convenient, but inefficient, ways of doping is the spin casting of a precursor mixture of components in solution, followed by solvent evaporation. Active control over this process holds the key to significant improvements over current poor doping efficiencies. Yet, an optimized control can only come from a detailed understanding of electronic interactions responsible for the low doping efficiencies. Here, we use two-dimensional nonlinear optical spectroscopy to examine these interactions in the course of the doping process by probing the solution mixture of doped organic semiconductors. A dopant accepts an electron from the semiconductor and the two ions form a duplex of interacting charges known as ion-pair complexes. Well-resolved off-diagonal peaks in the two-dimensional spectra clearly demonstrate the electronic connectivity among the ions in solution. This electronic interaction represents a well resolved electrostatically bound state, as opposed to a random distribution of ions. We developed a theoretical model to recover the experimental data, which reveals an unexpectedly strong electronic coupling of ∼250 cm -1 with an intermolecular distance of ∼4.5 Å between ions in solution, which is approximately the expected distance in processed films. The fact that this relationship persists from solution to the processed film gives direct evidence that Coulomb interactions are retained from the precursor solution to the processed films. This memory effect renders the charge carriers equally bound also in the film and, hence, results in poor doping efficiencies. This new insight will help pave the way towards rational tailoring of the electronic interactions to improve doping efficiencies in processed organic semiconductor thin films.

  6. NONLINEAR DYNAMICS OF ORGANIZATION DEVELOPMENT

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    Денис Антонович БУШУЕВ

    2016-02-01

    Full Text Available The nonlinear behavior of organizations in development projects is considered. The nonlinear behavior is initiated in the growth of organizations and requires a restructuring of governance in identifying dysfunctions. Such a restructuring is needed in the area of soft components, determining the organizational levels of competence in the management of projects, programs, portfolios and heads of the Project Management Office. An important component of the strategic development of the organization is the proposed concept for formation and management of development programs in the context according to their life cycle. It should take into account the non-linear behavior of the soft components of the system and violation of functional processes of the organization. The specific management syndromes of projects and programs are considered. Such as syndromes time management project linked to the singular points of the project. These syndromes are "shift to the right", "point of no return", "braking at the end of the project" and others.

  7. Development and Tissue Origins of the Mammalian Cranial Base

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    Iseki, S.; Bamforth, S. D.; Olsen, B. R.; Morriss-Kay, G. M.

    2008-01-01

    The vertebrate cranial base is a complex structure composed of bone, cartilage and other connective tissues underlying the brain; it is intimately connected with development of the face and cranial vault. Despite its central importance in craniofacial development, morphogenesis and tissue origins of the cranial base have not been studied in detail in the mouse, an important model organism. We describe here the location and time of appearance of the cartilages of the chondrocranium. We also examine the tissue origins of the mouse cranial base using a neural crest cell lineage cell marker, Wnt1-Cre/R26R, and a mesoderm lineage cell marker, Mesp1-Cre/R26R. The chondrocranium develops between E11 and E16 in the mouse, beginning with development of the caudal (occipital) chondrocranium, followed by chondrogenesis rostrally to form the nasal capsule, and finally fusion of these two parts via the midline central stem and the lateral struts of the vault cartilages. X-Gal staining of transgenic mice from E8.0 to 10 days post-natal showed that neural crest cells contribute to all of the cartilages that form the ethmoid, presphenoid, and basisphenoid bones with the exception of the hypochiasmatic cartilages. The basioccipital bone and non-squamous parts of the temporal bones are mesoderm derived. Therefore the prechordal head is mostly composed of neural crest-derived tissues, as predicted by the New Head Hypothesis. However, the anterior location of the mesoderm-derived hypochiasmatic cartilages, which are closely linked with the extra-ocular muscles, suggests that some tissues associated with the visual apparatus may have evolved independently of the rest of the “New Head”. PMID:18680740

  8. Organic cattle products: Authenticating production origin by analysis of serum mineral content.

    Science.gov (United States)

    Rodríguez-Bermúdez, Ruth; Herrero-Latorre, Carlos; López-Alonso, Marta; Losada, David E; Iglesias, Roberto; Miranda, Marta

    2018-10-30

    An authentication procedure for differentiating between organic and non-organic cattle production on the basis of analysis of serum samples has been developed. For this purpose, the concentrations of fourteen mineral elements (As, Cd, Co, Cr, Cu, Fe, Hg, I, Mn, Mo, Ni, Pb, Se and Zn) in 522 serum samples from cows (341 from organic farms and 181 from non-organic farms), determined by inductively coupled plasma spectrometry, were used. The chemical information provided by serum analysis was employed to construct different pattern recognition classification models that predict the origin of each sample: organic or non-organic class. Among all classification procedures considered, the best results were obtained with the decision tree C5.0, Random Forest and AdaBoost neural networks, with hit levels close to 90% for both production types. The proposed method, involving analysis of serum samples, provided rapid, accurate in vivo classification of cattle according to organic and non-organic production type. Copyright © 2018 Elsevier Ltd. All rights reserved.

  9. Legal Issues Related to Donation of Organs, Tissues and Cells of Human Origin

    Directory of Open Access Journals (Sweden)

    Gabriela Mironov

    2010-06-01

    Full Text Available Scientific developments, positive changes in attitude of the man and the new legal framework allow the donation of organs, tissues and cells of human origin. In this context it is necessary to clarifywhether the donation covered by the special law is, legally, one and the same as that covered by the Romanian Civil Code in force and qualified the successor’s right to accept or reject late withdrawals for transplantation. The right to life and physical integrity is personal patrimony; it is a subjective civil right that has no economic content and it cannot be measured in money. Consequently, the content of these rights can not be expressed in money, the property does not belong to their owner. Given the above view, "the right of disposal" to donation of organs, tissues and cells of human origin is an attribute of ownership, right to life and physical integrity, as a personal right that is an intimate attribute patrimonial related to the person’s right to dispose of his body as it wishes, within the law. Addressing these issues it is necessary to clarify the legal consequences of donating organs, tissues and cells of human origin, considering that medical activities are becoming more numerous.

  10. Intrinsically Disordered Proteins and the Origins of Multicellular Organisms

    Science.gov (United States)

    Dunker, A. Keith

    In simple multicellular organisms all of the cells are in direct contact with the surrounding milieu, whereas in complex multicellular organisms some cells are completely surrounded by other cells. Current phylogenetic trees indicate that complex multicellular organisms evolved independently from unicellular ancestors about 10 times, and only among the eukaryotes, including once for animals, twice each for green, red, and brown algae, and thrice for fungi. Given these multiple independent evolutionary lineages, we asked two questions: 1. Which molecular functions underpinned the evolution of multicellular organisms?; and, 2. Which of these molecular functions depend on intrinsically disordered proteins (IDPs)? Compared to unicellularity, multicellularity requires the advent of molecules for cellular adhesion, for cell-cell communication and for developmental programs. In addition, the developmental programs need to be regulated over space and time. Finally, each multicellular organism has cell-specific biochemistry and physiology. Thus, the evolution of complex multicellular organisms from unicellular ancestors required five new classes of functions. To answer the second question we used Key-words in Swiss Protein ranked for associations with predictions of protein structure or disorder. With a Z-score of 18.8 compared to random-function proteins, à differentiation was the biological process most strongly associated with IDPs. As expected from this result, large numbers of individual proteins associated with differentiation exhibit substantial regions of predicted disorder. For the animals for which there is the most readily available data all five of the underpinning molecular functions for multicellularity were found to depend critically on IDP-based mechanisms and other evidence supports these ideas. While the data are more sparse, IDPs seem to similarly underlie the five new classes of functions for plants and fungi as well, suggesting that IDPs were indeed

  11. INMARSAT - The International Maritime Satellite Organization: Origins and structure

    Science.gov (United States)

    Doyle, S. E.

    1977-01-01

    The third session of the International Conference on the Establishment of an International Maritime Satellite System established the International Maritime Satellite Organization (INMARSAT) in 1976. Its main functions are to improve maritime communications via satellite, thereby facilitating more efficient emergency communications, ship management, and maritime public correspondence services. INMARSAT's aims are similar to those of the Intergovernmental Maritime Consultative Organization (IMCO), the main United Nations organization dealing with maritime affairs. The specific functions of INMARSAT have been established by an Intersessional Working Group (IWG) which met three times between general conference meetings. Initial investment shares for the creation of INMARSAT were shared by the United States (17%), the United Kingdom (12%), the U.S.S.R. (11%), Norway (9.50%), Japan (8.45%), Italy (4.37%), and France (3.50%).

  12. Origin of size effect on efficiency of organic photovoltaics

    DEFF Research Database (Denmark)

    Manor, Assaf; Katz, Eugene A.; Tromholt, Thomas

    2011-01-01

    It is widely accepted that efficiency of organic solar cells could be limited by their size. However, the published data on this effect are very limited and none of them includes analysis of light intensity dependence of the key cell parameters. We report such analysis for bulk heterojunction sol...

  13. Structural Origins of Scintillation: Metal Organic Frameworks as a Nanolaboratory

    Science.gov (United States)

    2016-06-01

    adsorption of fluorphores within their pores, form exciplexes similar to those found in solution-based systems and can these serve as a tool to control the...selected due to their ability to form luminescent exciplexes with electron-accepting organic chromophores. Incorporation of these guests within the...and W2×(A4), exciplex , where W and A terms describe the peak weighting factors and amplitudes. The intensities were determined from the integrated

  14. Translanguaging: Origins and Development from School to Street and beyond

    Science.gov (United States)

    Lewis, Gwyn; Jones, Bryn; Baker, Colin

    2012-01-01

    The article traces the Welsh origins of "translanguaging" from the 1980s to the recent global use, analysing the development and extension of the term. It suggests that the growing popularity of the term relates to a change in the way bilingualism and multilingualism have ideologically developed not only among academics but also amid…

  15. Origin and organization of the SP-100 program

    International Nuclear Information System (INIS)

    Ambrus, J.H.

    1984-01-01

    The next step for occupying space is to build a space station. Energy demands for such a project grow larger the more often we look at them. To provide such high power for long periods of time is likely to require a nuclear reactor. The task force therefore looked around and asked, Is there a space nuclear reactor. JPL and LANL started talking to each other. After a lot of negotiation, the three agencies - DOE, NASA, and DARPA - created a tri-agency program to develop space reactor power system technology

  16. Origin,

    Directory of Open Access Journals (Sweden)

    Artur de Vargas Giorgi

    2011-02-01

    Full Text Available This essay tightens the “origin” concept, its manifestation through puzzles and their relationship to techniques of reproduction. Contrary to the hegemonic critique of aesthetic and cultural objects – critique that, settled on the appearance and notions of identity, tradition, canon, etc., undervalues the reproductions of "originals" –, the aim is to deliver these objects from formal hierarchization dispositives, that is, release them of what is ideal and positively imposed, so that the reproducibility is potentiated as producer of singularities, of apparitions. The effort is to keep the undecided character of puzzles (bodies, texts, images in which the origin is manifest, so that the logic of the spectacle is reverted into sense opening, instance in which the aesthetic becomes a “performance” before contemporary complexity. With the reproducibility, an origin survives in passage: continually restored, but incomplete, present in trace, in absence.

  17. Development of the nervus terminalis: origin and migration.

    Science.gov (United States)

    Whitlock, Kathleen E

    2004-09-01

    The origin of the nervus terminalis is one of the least well understood developmental events involved in generating the cranial ganglia of the forebrain in vertebrate animals. This cranial nerve forms at the formidable interface of the anteriormost limits of migrating cranial neural crest cells, the terminal end of the neural tube and the differentiating olfactory and adenohypophyseal placodes. The complex cellular interactions that give rise to the various structures associated with the sensory placode (olfactory) and endocrine placode (adenohypophysis) surround and engulf this enigmatic cranial nerve. The tortured history of nervus terminalis development (see von Bartheld, this issue, pages 13-24) reflects the lack of consensus on the origin (or origins), as well as the experimental difficulties in uncovering the origin, of the nervus terminalis. Recent technical advances have allowed us to make headway in understanding the origin(s) of this nerve. The emergence of the externally fertilized zebrafish embryo as a model system for developmental biology and genetics has shed new light on this century-old problem. Coupled with new developmental models are techniques that allow us to trace lineage, visualize gene expression, and genetically ablate cells, adding to our experimental tools with which to follow up on studies provided by our scientific predecessors. Through these techniques, a picture is emerging in which the origin of at least a subset of the nervus terminalis cells lies in the cranial neural crest. In this review, the data surrounding this finding will be discussed in light of recent findings on neural crest and placode origins. Copyright 2004 Wiley-Liss, Inc.

  18. Low-energy positron beams - origins, developments and applications

    International Nuclear Information System (INIS)

    Beling, C.D.; Charlton, M.

    1987-01-01

    Over the last 15 years there have been rapid advances in the technology associated with low-energy positron beams. The origins of these advances, and some of the major developments, are discussed. Some applications from the diverse fields of surface physics, atomic scattering and positronium studies are highlighted. (author)

  19. An overview: origins and development of green chemistry

    NARCIS (Netherlands)

    Linthorst, J.A.

    2009-01-01

    This article provides an overview of the origins and development of green chemistry. Aiming to contribute to the understanding of green chemistry, basically from a historical point of view, this overview argues that contextual influences and the user friendliness of the term are drivers for the

  20. Local and/or organic: A study on consumer preferences for organic food and food from different origins

    OpenAIRE

    Feldmann , Corinna; Hamm, Ulrich

    2014-01-01

    The purpose of this paper is to get a deeper insight into consumer preferences for different food products varying in their places of origin (i.e. local, Germany, neighbouring country, non-EU country) and production practices (i.e. organic vs. non-organic). Therefore, consumer surveys combined with choice experiments were conducted with 641 consumers in eight supermarkets in different parts of Germany. Multinomial and mixed logit models were estimated to draw conclusions on the preference str...

  1. Diagnosing Organization-Environment "Fit": Implications for Organization Development

    Science.gov (United States)

    Gabarro, John J.

    1974-01-01

    This article has attempted to: (1) describe several dimensions of organization-environment fit; (2) describe some concepts which can be used in diagnosing the degree to which a school system's organization matches the demands and needs of its environment; (3) present some implications of such a diagnosis for OD [organizational development]…

  2. Origin and early development of the chicken adenohypophysis.

    Directory of Open Access Journals (Sweden)

    Luisa eSanchez-Arrones

    2015-02-01

    Full Text Available The adenohypophysis (ADH is an important endocrine organ involved in the regulation of many physiological processes. The late morphogenesis of this organ at neural tube stages is well known: the epithelial ADH primordium is recognized as an invagination of the stomodeal roof (Rathke’s pouch, whose walls later thicken and differentiate as the primordium becomes pediculated, and then fully separated from the stomodeum. The primordium attaches to the pial surface of the basal hypothalamus, next to the neurohypophyseal field (NH; future posterior pituitary, from which it was previously separated by migrating prechordal plate cells. Once the NH evaginates, the ADH surrounds it and jointly forms with it the pituitary gland. In contrast, little is known about the precise origin of the ADH precursors at neural plate stages and how the primordium reaches the stomodeum. For that reason, we produced in the chicken a specific ADH fate map at early neural plate stages, which was amplified with gene markers. By means of experiments labelling the mapped presumptive ADH, we were able to follow the initial anlage into its transformation into Rathke’s pouch. The ADH origin was corroborated to be strictly extraneural, i.e., to lie at stage HH4/5 outside of the anterior neural plate within the pre-placodal field. The ADH primordium is fully segregated from the anterior neural border cells and the neighboring olfactory placodes both in terms of precursor cells and molecular profile from head fold stages onwards. The placode becomes visible as a molecularly characteristic ectodermal thickening from stage HH10 onwards. The onset of ADH genoarchitectonic regionalization into intermediate and anterior lobes occurs at closed neural tube stages.

  3. On the origin of the organic-rich material on Ceres

    Science.gov (United States)

    Marchi, Simone; Bowling, Timothy; De Sanctis, Maria Cristina

    2017-10-01

    The detection of localized, organic-rich material on Ceres [1] poses an interesting conundrum. Either the organic-rich material has an exogenous origin, and thus it has been delivered to Ceres after its formation; or it has an endogenous origin, and thus it has been synthesized and/or concentrated in a specific location on Ceres via internal processes.Both scenarios have shortfalls, indicating we may ultimately be missing how organic matter has been formed, transported and reworked in solar system objects. The very location of Ceres at the boundary between the inner and outer solar system, and its intriguing composition characterized by clays, sodium- and ammonium-carbonates [2], suggest Ceres experienced a very complex chemical evolution. The role of organics in this evolution is not fully understood, with important astrobiological implications [3].Here we investigate the viability of organics delivery to Ceres via asteroidal/cometary impactors. We will present iSALE shock physics code [4-5] simulations that explore a range of impact parameters, such as impactor sizes and velocities, and discuss the likelihood of organics delivery. We find that comet-like projectiles, with relatively high impact velocities, are expected to lose almost all of their organics due to shock compression. Asteroidal-like impactors, with lower incident velocities, can retain 20-30% of their pre-impact organic material during delivery, especially for small impactors and very oblique impact angles. However, the spatial distribution of organics on Ceres seems difficult to reconcile with delivery from small main belt asteroids. These findings corroborate an endogenous origin for the organics on Ceres.[1] De Sanctis M. C. et al. Science 355, 2016. [2] De Sanctis M. C. et al. Nature 536, 2016. [3] Castillo-Rogez J. C. et al. Planetary Science Vision 2050 Workshop 2017 (LPI Contrib. No. 1989). [4] Amsden A. et al. LANL Report, LA-8095, 1980. [5] Collins G. S. et al. MAPS 39, 2004.

  4. Self-organizing periodicity in development: organ positioning in plants.

    Science.gov (United States)

    Bhatia, Neha; Heisler, Marcus G

    2018-02-08

    Periodic patterns during development often occur spontaneously through a process of self-organization. While reaction-diffusion mechanisms are often invoked, other types of mechanisms that involve cell-cell interactions and mechanical buckling have also been identified. Phyllotaxis, or the positioning of plant organs, has emerged as an excellent model system to study the self-organization of periodic patterns. At the macro scale, the regular spacing of organs on the growing plant shoot gives rise to the typical spiral and whorled arrangements of plant organs found in nature. In turn, this spacing relies on complex patterns of cell polarity that involve feedback between a signaling molecule - the plant hormone auxin - and its polar, cell-to-cell transport. Here, we review recent progress in understanding phyllotaxis and plant cell polarity and highlight the development of new tools that can help address the remaining gaps in our understanding. © 2018. Published by The Company of Biologists Ltd.

  5. Thapsigargin, origin, chemistry, structure-activity relationships and prodrug development

    DEFF Research Database (Denmark)

    Doan, Thi Quynh Nhu; Christensen, Søren Brøgger

    2015-01-01

    Thapsigargin was originally isolated from the roots of the Mediterranean umbelliferous plant Thapsia garganica in order to characterize the skin irritant principle. The biological activity was related to the subnanomolar affinity for the sarco-endoplasmic reticulum calcium ATPase. Prolonged......) targeted against prostate cancer. Conjugation to a peptide, which only is a substrate for prostate specific membrane antigen enabled development of a prodrug (G202), which is targeted towards a number of cancer diseases including hepatocellular carcinoma. G202 has under the name of mipsagargin in clinical...

  6. Evolutionary origins and early development of number processing

    CERN Document Server

    Geary, David C; Mann Koepke, Kathleen

    2014-01-01

    The first volume in this ground-breaking series focuses on the origins and early development of numerical cognition in non-human primates, lower vertebrates, human infants, and preschool children. The text will help readers understand the nature and complexity of these foundational quantitative concepts and skills along with evolutionary precursors and early developmental trajectories. Brings together and focuses the efforts and research of multiple disciplines working in math cognition.The contributors bring vast knowledge and experience to bear on resolving extant

  7. Distribution and origin of suspended matter and organic carbon pools in the Tana River Basin, Kenya

    NARCIS (Netherlands)

    Tamooh, F.; Van den Meersche, K.; Meysman, F.; Marwick, T.R.; Borges, A.V.; Merckx, R.; Dehairs, F.; Schmidt, S.; Nyunja, J.; Bouillon, S.

    2012-01-01

    We studied patterns in organic carbon pools and their origin in the Tana River Basin (Kenya), in February 2008 (dry season), September–November 2009 (wet season), and June–July 2010 (end of wet season), covering the full continuum from headwater streams to lowland mainstream sites. A consistent

  8. Organic material in meteorites and the link to the origin of life

    Directory of Open Access Journals (Sweden)

    Remusat L.

    2014-02-01

    Full Text Available Life requires specific conditions that have been, so far, only proven to meet on Earth. Though the chemical elements required to form living organism (C, H, N, O, S, etc are widespread in the universe, the molecules that are crucial for Life, like nucleobases or amino acids, may not be so ubiquitous. The question of the formation of small and complex molecules is highly relevant to understand the process of Life origin. Carbonaceous chondrites are a class of meteorites rich in organic compounds and host potential precursors for the emergence of Life (organic matter and water. They could have been the source of complex molecules on the early Earth. This contribution will describe the main properties of the organic matter recovered from carbonaceous chondrites. However, the isotopic and molecular record of organic compounds is faded by secondary processes that occurred on the parent body of these meteorites. This results in complex signatures that raise multiple questions about the origin of organic compounds in the Solar System.

  9. An estimation of influence of humic acid and organic matter originated from bentonite on samarium solubility

    International Nuclear Information System (INIS)

    Kanaji, Mariko; Sato, Haruo; Sasahira, Akira

    1999-10-01

    Organic acids in groundwater are considered to form complexes and increase the solubility of radionuclides released from vitrified waste in a high-level radioactive waste (HLW) repository. To investigate whether the solubility of samarium (Sm) is influenced by organic substances, we measured Sm solubility in the presence of different organic substances and compared those values with results from thermodynamic predictions. Humic acid (Aldrich) is commercially available and soluble organic matter originated from bentonite were used as organic substances in this study. Consequently, the solubility of Sm showed a tendency to apparently increase with increasing the concentration of humic acid, but in the presence of carbonate, thermodynamic predictions suggested that the dominant species are carbonate complexes and that the effect of organic substances are less than that of carbonate. Based on total organic carbon (TOC), the increase of Sm solubility measured with humic acid (Aldrich) was more significant than that in the case with soluble organic matter originated from bentonite. Since bentonite is presumed to include also simple organic matters of which stability constant for forming complexes is low, the effect of soluble organic matter originated from bentonite on the solubility of Sm is considered to be less effective than that of humic acid (Aldrich). Experimental values were compared with model prediction, proposed by Kim, based on data measured in a low pH region. Tentatively we calculated the increase in Sm solubility assuming complexation with humic acid. Trial calculations were carried out on the premise that the complexation reaction of metal ion with humic acid is based on neutralization process by 1-1 complexation. In this process, it was assumed that one metal ion coordinates with one unit of complexation sites which number of proton exchange sites is equal to ionic charge. Consequently, Kim's model indicated that carbonate complexes should be dominant

  10. Measuring originality: common patterns of invention in research and technology organizations

    Energy Technology Data Exchange (ETDEWEB)

    Tang, D.L.; Wiseman, E.; Keating, T.; Archambeault, J.

    2016-07-01

    The National Research Council of Canada (NRC) co-chairs an international working group on performance benchmarking and impact assessment of Research and Technology Organizations (RTO). The Knowledge Management branch of the NRC conducted the patent analysis portion of the benchmarking study. In this paper, we present a Weighted Originality index that can more accurately measure the spread of technological combinations in terms of hierarchical patent classifications. Using this patent indicator, we revealed a common pattern of distribution of invention originality in RTOs. Our work contributes to the methodological advancement of patent measures for the scientometric community. (Author)

  11. Origin and role of gap states in organic semiconductor studied by UPS: as the nature of organic molecular crystals

    International Nuclear Information System (INIS)

    Yang, Jin-Peng; Bussolotti, Fabio; Kera, Satoshi; Ueno, Nobuo

    2017-01-01

    This article reviews experimental studies on ‘bridging electronic structure and charge transport property of organic semiconductors’ performed using ultraviolet photoelectron spectroscopy (UPS) and related methods mainly in Chiba University, Japan, in particular on the investigation of the origin and the role of electronic states existing in the highest occupied molecular orbital band–lowest unoccupied molecular orbital band (HOMO–LUMO) gap. We summarize experimental observations including direct measurements of ‘invisible’ gap states with ultrahigh sensitivity UPS, which demonstrate that there exist intrinsic gap states in organic semiconductors. We firstly describe the nature of organic molecular solids to understand features of organic semiconductors because such intrinsic gap states are a result of the interplay of these features, which give the principal difference between the organic semiconductor and inorganic counterpart. We then discuss (i) the origin and role of the band gap states in relation to intermolecular interaction/band dispersion and electron–phonon coupling, (ii) the Fermi level pinning issue in organic semiconductors, and (iii) the method of computing the Fermi level position within the HOMO–LUMO gap for experimental groups. The gap states of organic semiconductors appear easily when a weak perturbation is applied to the organic system, namely by contact with other material, by injecting a charge, by elevating temperature, and by exposure to 1 atm gas. What we finally found is that tailing states of HOMO and LUMO always exist, and their energy distributions must not be symmetric; they thus produce a larger Fermi level shift from the mid gap position than previously thought. Furthermore, as shown by computational work, Fermi level pinning , which is a well-known phenomena in semiconductor devices field, occurs in weakly interacting organic/conductor systems without any gap states if the system temperature is not zero ( T

  12. Origin and role of gap states in organic semiconductor studied by UPS: as the nature of organic molecular crystals

    Science.gov (United States)

    Yang, Jin-Peng; Bussolotti, Fabio; Kera, Satoshi; Ueno, Nobuo

    2017-10-01

    This article reviews experimental studies on ‘bridging electronic structure and charge transport property of organic semiconductors’ performed using ultraviolet photoelectron spectroscopy (UPS) and related methods mainly in Chiba University, Japan, in particular on the investigation of the origin and the role of electronic states existing in the highest occupied molecular orbital band-lowest unoccupied molecular orbital band (HOMO-LUMO) gap. We summarize experimental observations including direct measurements of ‘invisible’ gap states with ultrahigh sensitivity UPS, which demonstrate that there exist intrinsic gap states in organic semiconductors. We firstly describe the nature of organic molecular solids to understand features of organic semiconductors because such intrinsic gap states are a result of the interplay of these features, which give the principal difference between the organic semiconductor and inorganic counterpart. We then discuss (i) the origin and role of the band gap states in relation to intermolecular interaction/band dispersion and electron-phonon coupling, (ii) the Fermi level pinning issue in organic semiconductors, and (iii) the method of computing the Fermi level position within the HOMO-LUMO gap for experimental groups. The gap states of organic semiconductors appear easily when a weak perturbation is applied to the organic system, namely by contact with other material, by injecting a charge, by elevating temperature, and by exposure to 1 atm gas. What we finally found is that tailing states of HOMO and LUMO always exist, and their energy distributions must not be symmetric; they thus produce a larger Fermi level shift from the mid gap position than previously thought. Furthermore, as shown by computational work, Fermi level pinning, which is a well-known phenomena in semiconductor devices field, occurs in weakly interacting organic/conductor systems without any gap states if the system temperature is not zero (T  >  0). We

  13. A review of observations of organic matter in fogs and clouds: Origin, processing and fate

    Science.gov (United States)

    Herckes, Pierre; Valsaraj, Kalliat T.; Collett, Jeffrey L.

    2013-10-01

    While fog and cloud composition has been studied for decades, most of the research was limited to inorganic species and fog acidity. Recently the focus has shifted towards organic matter in the atmospheric aqueous phase of fogs and clouds: its origin, reactivity and fate. An impressive number of fog and cloud chemistry observational studies have been performed over the last decade throughout the world. In the present work we will review the state of knowledge of atmospheric organic matter processing by fogs, with a focus on field observations. We start by reviewing observational studies in general and then discuss our knowledge on the occurrence of organic matter in fogs, its solubility, characterization and molecular speciation. Organic carbon concentrations can vary widely from approximately 1 mg C/L in remote marine environments to more than 100 mg C/L in polluted radiation fogs, accounting for a substantial part of fogwater solutes. The carbonaceous material can enter the droplets from the gas and particle phase and the scavenging behavior of fogs will be detailed. Observational studies showed evidence of aqueous phase transformation of organic material, in particular secondary organic aerosol (SOA) generation, in fog. Recent observations of biological material in fog suggest also an impact of biological processing within the droplets on fog organic matter. The review will end with a discussion of the impact of fog on the deposition fluxes of organic material and hence its atmospheric lifetime.

  14. Tracing the Origins of Nitrogen Bearing Organics Toward Orion KL with Alma

    Science.gov (United States)

    Carroll, Brandon; Crockett, Nathan; Wilkins, Olivia H.; Bergin, Edwin; Blake, Geoffrey

    2017-06-01

    A comprehensive analysis of a broadband 1.2 THz wide spectral survey of the Orion Kleinmann-Low nebula (Orion KL) has shown that nitrogen bearing complex organics trace systematically hotter gas than O-bearing organics toward this source. The origin of this O/N dichotomy remains a mystery. If complex molecules originate from grain surfaces, N-bearing species may be more difficult to remove from grain surfaces than O-bearing organics. Theoretical studies, however, have shown that hot (T=300 K) gas phase chemistry can produce high abundances of N-bearing organics while suppressing the formation of O-bearing complex molecules. In order to distinguish these distinct formation pathways we have obtained extremely high angular resolution observations of methyl cyanide (CH_3CN) using the Atacama Large Millimeter/Submillimeter Array (ALMA) toward Orion KL. By simultaneously imaging ^{13}CH_3CN and CH_2DCN we map the temperature structure and D/H ratio of CH_3CN. We will present updated results of these observations and discuss their implications for the formation of N-bearing organics in the interstellar medium.

  15. Extraterrestrial Organic Chemistry: From the Interstellar Medium to the Origins of Life

    Science.gov (United States)

    Pohorille, Andrew; DeVincenzi, Donald L. (Technical Monitor)

    2000-01-01

    Extraterrestrially delivered organics in the origin of cellular life. Various processes leading to the emergence of cellular life from organics delivered from space to earth or other planetary bodies in the solar system will be reviewed. The focus will be on: (1) self-assembly of amphiphilic material to vesicles and other structures, such as micelles and multilayers, and its role in creating environments suitable for chemical catalysis, (2) a possible role of extraterrestrial delivery of organics in the formation of the simplest bioenergetics (3) mechanisms leading from amino acids or their precursors to simple peptides and, subsequently, to the evolution of metabolism. These issues will be discussed from two opposite points of view: (1) Which molecules could have been particularly useful in the protobiological evolution; this may provide focus for searching for these molecules in interstellar media. (2) Assuming that a considerable part of the inventory of organic matter on the early earth was delivered extraterrestrially, what does relative abundance of different organics in space tell us about the scenario leading to the origin of life.

  16. Using fluorescent dissolved organic matter to trace and distinguish the origin of Arctic surface waters

    DEFF Research Database (Denmark)

    Goncalves-Araujo, Rafael; Granskog, Mats A.; Bracher, Astrid

    2016-01-01

    were performed in the Fram and Davis Straits, and on the east Greenland Shelf (EGS), in late summer 2012/2013. Meteoric (f(mw)), sea-ice melt, Atlantic and Pacific water fractions were determined and the fluorescence properties of dissolved organic matter (FDOM) were characterized. In Fram Strait...... and EGS, a robust correlation between visible wavelength fluorescence and f(mw) was apparent, suggesting it as a reliable tracer of polar waters. However, a pattern was observed which linked the organic matter characteristics to the origin of polar waters. At depth in Davis Strait, visible wavelength FDOM...

  17. Modeling of Possible Conditions for Origin of First Organic Forms in hot Mineral Water

    OpenAIRE

    Ignat Ignatov; Oleg Mosin

    2014-01-01

    The composition of water, its temperature and pH value was analyzed in experiments with modelling of primary hydrosphere and possible conditions for origin of first organic forms in hot mineral water. For this aim the authors performed experiments with hot mineral and seawater from Bulgaria by IR-spectrometry (DNES-method). As model systems were used cactus juice of Echinopsis pachanoi and Mediterranean jellyfish Cotylorhiza tuberculata. It was considered the reactions of condensation and deh...

  18. The microscopic origin of self-organized nanostripe pattern formation on an electropolished aluminium surface

    International Nuclear Information System (INIS)

    Sarkar, Jaya; Basumallick, A; Khan, Gobinda Gopal

    2009-01-01

    By correlating the experimental evidence obtained from atomic force microscopy, conventional x-ray diffraction, and a surface sensitive modified x-ray diffraction technique with the results of density functional theory based computations, we demonstrate that self-organized nanostripe patterns formed on the electropolished surface of aluminium originate as a consequence of relaxation and reconstruction of the new surfaces exposed and textural changes at the surface caused by the dissolution during polishing.

  19. Development Internal Problems of Shanghay Cooperation Organization

    Directory of Open Access Journals (Sweden)

    Oksana Y. Kolegova

    2015-01-01

    Full Text Available The article analyzes the main internal problems of the Shanghai Cooperation Organization. Particular attention is paid to the conflict of interests of the participating countries, as well as identifying obstacles to strengthen the organization and increase its influence in the international arena. The international organizations are created by the states to meet mutual problems in the course of interstate relations requiring regular cooperation mechanism. Given the background of the Organization, it is important to emphasize that the main reason for the establishment of the Shanghai organization was the need for the united front against the strengthening of the region at the turn of centuries against dangerous trends of terrorism, extremism, separatism, the growth of organized crime. Despite the conflict of interests and the internal and external development challenges thirteen-year history of evolution of the SCO, to some extent proves its effectiveness, moreover, there are the preconditions for its consistent transition to a more comprehensive organization.

  20. Process Consultation: Its Role in Organization Development.

    Science.gov (United States)

    Schein, Edgar H.

    This volume focuses on the process by which the consultant builds readiness for organizational development (OD) programs, actually conducts training, and works with the key individuals of an organization as part of an OD program. Part I describes in some detail the human processes in organizations--communication, functional roles of group members,…

  1. Contemporary Organized Crime. : Developments, Challenges and Responses.

    NARCIS (Netherlands)

    Nelen, Hans; Siegel, Dina

    2017-01-01

    This is the third publication (after Siegel et al. (eds.) (2003) Global Organized Crime. Trends and Developments; and Siegel and Nelen (eds.) (2008). Organized Crime: Culture, Markets and Policies) in which the most relevant papers that were presented during seminars of the Centre for Information

  2. Organic sediments of the equatorial east Atlantic: Effects of origin, transport, diagenesis, and climate

    International Nuclear Information System (INIS)

    Westerhausen, L.

    1992-01-01

    The origins and diagenesis of organic matter in recent sediments of the equatorial Eastern Atlantic are assessed on the basis of the 13 C/ 12 C composition of the organic carbon (δ 13 C TOC ), the C/N ratio, and molecular biomarkers from terrigenic and marine sources. Also investigated was the effect of global climate on the 13 C/ 12 C ratios of marine organic carbon and on the origins of organic matter on sedimentary cores. The terrigenic fraction of organic carbon is calculated using a binary δ 13 C TOC mixing model. To begin with, the δ 13 C TOC values were standardized to a uniform surface water temperature and water depth. The calculated terrigenic TOC fractions amount to more than 60% for shelf sediments off the coast of Eastern Liberia, Ivory Coast, and the continental shelf of Gabun. The higher terrigenic TOC fractions of up to 20% in recent sediments on the continental shelf along the coast of Guinea to Ivory Coast are interpreted in terms of a transport of terrigenic substances in down hill direction and parallel to the coast. The effects of the global climate on the TOC accumulation rates and on the 13 C/ 12 C ratio of organic carbon were investigated in a pelogic sedimentary core (M16772) from the tropical Eastern Atlantic. Prior to this, the δ 13 C TOC values were standardized to a uniform surface temperature and a uniform 13 C/ 12 C ratio of the dissolved inorganic carbon using the UK 37 index and the δ 13 C values of G.ruber. During the cold periods the export production increases, which - together with the low CO 2 partial pressure in the atmosphere, and thus also in the surface water -induces 13 C accumulation in the marine organic carbon. There is nothing to suggest an effect of 13 C-accumulating phytoplancton, e.g. dinoflagellats, on the 13 C/ 12 C ratio. (orig./KW). 32 figs., 8 tabs [de

  3. Organization Development: A Case Study in Blockages.

    Science.gov (United States)

    McIntyre, Martin

    1981-01-01

    Organization Development is a management science that defines and solves organizational problems. Procedures include: (1) diagnosis of problem; (2) gathering of data related to problem; (3) obtaining feedback; (4) developing various change strategies; (5) developing an action plan; and (6) implementing the plan. (CJ)

  4. Developing leadership talent in healthcare organizations.

    Science.gov (United States)

    Wells, Wendy; Hejna, William

    2009-01-01

    Effective initiatives for developing and retaining leadership talent are built around five supporting elements: Identification of key leader competencies. Effective job design. A strong focus on leadership recruitment, development, and retention. Leadership training and development throughout all levels of the organization. Ongoing leadership assessment and performance management.

  5. Gamification - Environmental and Sustainable Development Organizations Could Do More

    Science.gov (United States)

    Ziegler, C. R.; Miller, C. A.; Kilaru, V.; French, R. A.; Costanza, R.; Brookes, A.

    2013-12-01

    The use of digital games to foster sustainable development and environmental goals has grown over the last 10 years. Innovative thinking and the origins of 'serious games,' 'games for change' and 'gamification' are partly rooted in movies and science fiction. Existing games illustrate a spectrum of approaches: for example, World Food Programme's FoodForce and University of Washington's Foldit. Environmental organizations globally (e.g. US EPA) have dabbled with game development and gamification, but have only touched the tip of the iceberg, particularly when compared to the success of the commercial gaming industry. We explore: 1) the intersection of environmental organization mission statements in the context of gamification efforts , 2) some examples of existing games, from simple to complex, 3) business model approaches (e.g. game development partnerships with academia, private industry, NGOs, etc.), 4) barriers, and 5) benefits of a more concerted and technologically-advanced approach to gamification for environmental organizations.

  6. Role of effluent organic matter in the photochemical degradation of compounds of wastewater origin.

    Science.gov (United States)

    Bodhipaksha, Laleen C; Sharpless, Charles M; Chin, Yu-Ping; MacKay, Allison A

    2017-03-01

    The photoreactivity of treated wastewater effluent organic matter differs from that of natural organic matter, and the indirect phototransformation rates of micropollutants originating in wastewater are expected to depend on the fractional contribution of wastewater to total stream flow. Photodegradation rates of four common compounds of wastewater origin (sulfamethoxazole, sulfadimethoxine, cimetidine and caffeine) were measured in river water, treated municipal wastewater effluent and mixtures of both to simulate various effluent-stream water mixing conditions that could occur in environmental systems. Compounds were chosen for their unique photodegradation pathways with the photochemically produced reactive intermediates, triplet-state excited organic matter ( 3 OM*), singlet oxygen ( 1 O 2 ), and hydroxyl radicals (OH). For all compounds, higher rates of photodegradation were observed in effluent relative to upstream river water. Sulfamethoxazole degraded primarily via direct photolysis, with some contribution from OH and possibly from carbonate radicals and other unidentified reactive intermediates in effluent-containing samples. Sulfadimethoxine also degraded mainly by direct photolysis, and natural organic matter appeared to inhibit this process to a greater extent than predicted by light screening. In the presence of effluent organic matter, sulfadimethoxine showed additional reactions with OH and 1 O 2 . In all water samples, cimetidine degraded by reaction with 1 O 2 (>95%) and caffeine by reaction with OH (>95%). In river water mixtures, photodegradation rate constants for all compounds increased with increasing fractions of effluent. A conservative mixing model was able to predict reaction rate constants in the case of hydroxyl radical reactions, but it overestimated rate constants in the case of 3 OM* and 1 O 2 pathways. Finally, compound degradation rate constants normalized to the rate of light absorption by water correlated with E 2 /E 3 ratios

  7. Origin and composition of particulate organic matter in a macrotidal turbid estuary: The Gironde Estuary, France

    Science.gov (United States)

    Savoye, Nicolas; David, Valérie; Morisseau, François; Etcheber, Henri; Abril, Gwenaël; Billy, Isabelle; Charlier, Karine; Oggian, Georges; Derriennic, Hervé; Sautour, Benoît

    2012-08-01

    At the interface between continent and ocean, estuaries receive particles, and especially particulate organic matter (POM) originating from these two reservoirs, but also produce POM, through autochthonous primary production. The origin and composition of surface POM in the Gironde Estuary (SW France) and the environmental forcing of its variability was investigated using the data set produced by the French Coastal Monitoring Network SOMLIT (Service d'Observation en Milieu LITtoral; monthly like sampling during years 2007-2009). This estuary is considered as a model of macrotidal turbid estuaries. Using elemental and isotopic composition of the POM, we estimated that, at the inner estuary space scale and inter-annual time scale, surface particulate organic carbon (POC) was composed of terrestrial POM originated from the turbidity maximum (96.4%; refractory POC) and flood events (1.6%; labile and refractory POC), and of riverine (0.1%), estuarine (0.8%) and marine (1.1%) phytoplankton, i.e. that POC was 98% and 2% of terrestrial and phytoplankton origin, respectively. However, there was a clear spatial gradient: the phytoplankton contribution increases from ca. 1% in the upper and middle estuary to 8.5% in the lower estuary, where light condition is more favourable to plankton growth. The low contribution of phytoplankton to the POC is a characteristic of the Gironde estuary and contrast with other large temperate estuaries. Statistical analysis indicates that salinity, river flow and SPM concentration, and thus associated hydro-dynamic and sedimentary processes, were the only environmental forcings to the composition of surface POC in this system, at intra- and inter-annual time scale. In contrast, temperature and nutrient concentrations, and thus associated processes, do not force this composition of POC. By combining POC fluxes entering the inner estuary (literature data), POC loss as dissolved organic carbon and CO2 and as sediment trapping within the inner

  8. Petroleum-related origin for uraniferous organic-rich nodules of Southwestern Oklahoma

    International Nuclear Information System (INIS)

    Curiale, J.A.; Bloch, S.; Harrison, W.E.; Rafalska-Bloch, J.

    1983-01-01

    Geologic field relations and geochemical analyses imply a petroleum-related origin for the organic matter of uraniferous nodules in the Permian Hennessey Group red beds in Kiowa County, Oklahoma. The local presence of crude oil in the shallow subsurface and the absence of local occurrences of plant debris suggest a hydrocarbon-related origin for these nodules. Several oil seeps in the general vicinity of the study area indicate that major steep reverse faults near the nodule site may have provided vertical conduits for petroleum migration from deeper zones. Geochemical analyses of the uraniferous nodules, including infrared spectroscopy and elemental analysis, reveal characteristics of both coal and petroleum. Carbon isotopic analyses favor a petroleum-related origin. A model incorporating field and geochemical evidence is suggested whereby crude oil, migrating from depth, is initially altered near the surface to a more viscous material. Concurrently migrating uranium-bearing ground water is then stripped of its uranium by the degraded petroleum. Therefore, presence of such nodules in the shallow subsurface may suggest buried petroleum deposits. Confirmation of this model must await further study of the effects of radiation damage on organic matter

  9. Origins and development of the Cauchy problem in general relativity

    International Nuclear Information System (INIS)

    Ringström, Hans

    2015-01-01

    The seminal work of Yvonne Choquet-Bruhat published in 1952 demonstrates that it is possible to formulate Einstein's equations as an initial value problem. The purpose of this article is to describe the background to and impact of this achievement, as well as the result itself. In some respects, the idea of viewing the field equations of general relativity as a system of evolution equations goes back to Einstein himself; in an argument justifying that gravitational waves propagate at the speed of light, Einstein used a special choice of coordinates to derive a system of wave equations for the linear perturbations on a Minkowski background. Over the following decades, Hilbert, de Donder, Lanczos, Darmois and many others worked to put Einstein's ideas on a more solid footing. In fact, the issue of local uniqueness (giving a rigorous justification for the statement that the speed of propagation of the gravitational field is bounded by that of light) was already settled in the 1930s by the work of Stellmacher. However, the first person to demonstrate both local existence and uniqueness in a setting in which the notion of finite speed of propagation makes sense was Yvonne Choquet-Bruhat. In this sense, her work lays the foundation for the formulation of Einstein's equations as an initial value problem. Following a description of the results of Choquet-Bruhat, we discuss the development of three research topics that have their origin in her work. The first one is local existence. One reason for addressing it is that it is at the heart of the original paper. Moreover, it is still an active and important research field, connected to the problem of characterizing the asymptotic behaviour of solutions that blow up in finite time. As a second topic, we turn to the questions of global uniqueness and strong cosmic censorship. These questions are of fundamental importance to anyone interested in justifying that the Cauchy problem makes sense globally. They are

  10. Superficiary Right of Building: Origin and Development in Central Europe

    Directory of Open Access Journals (Sweden)

    Petr Pavel

    2016-06-01

    Full Text Available The Czech Republic has been dealing for the last four years with a legal revolution in the field of private law. A new Civil Code was adopted in 2012 and many new and forgotten legal figures were restored in the text of the code. An interesting example of forgotten legal figures is the superficiary right of building, which has again entered the legal order of the Czech Republic after a long one hundred years. Unlike the Act on the Superficiary Right of Building of 1912, the new Civil Code extends the scope of persons that may create the superficiary right of building to their land. This should eliminate the obstacle that has substantially limited its wider use. The superficiary right of building is not likely to become a legal concept very frequently seen in public registers. The aim of this paper is, therefore, a reflection on divided ownership and the purpose and genesis of the superficiary right of building in relation to its origins, as well as a prediction of future developments of this legal concept in the real estate market. To analyse the concept, the paper employs formal and legal methods (logical, grammatical and historical method. A comparative study is conducted in the spirit of the comparative method. The superficiary right of building is a suitable complement to the range of options of property rights offered by the new Civil Code. The author concludes that the use of the superficiary right of building, although not limited in comparison with the 1912 Act, will likely be less frequent and focused on longer-term projects.

  11. Development Professionals at Religiously Based Nonprofit Organizations

    Directory of Open Access Journals (Sweden)

    Jim Pinder

    2012-09-01

    Full Text Available The study of why a fundraising professional would choose to leave his or her employer is critical to the ongoing success of religiously based nonprofit organizations as they work to achieve their mission. Without continuity in the donor relationship, donors will likely leave the organization or become disenfranchised. This study focuses on development professionals at Seventh-Day Adventist institutions across North America. The results of this study are applicable to other religiously based nonprofit organizations. The present article reveals the reasons affecting employee retention and proposes approaches to mitigate the loss of valuable employees. Data were gathered using a structured online survey and analyzed for its descriptive outcomes.

  12. The Enantiomeric Ratios of Meteoritic Organic Compounds: Their Possible Roles in the Origin of Life

    Science.gov (United States)

    Cooper, George

    2012-01-01

    This talk will give an overview of the enantiomer (mirror-image) ratios of organic compounds in meteorites and also describe the results of the present work in my lab. The primary focus will be on sugar derivatives (sugar acids) of carbonaceous meteorites. Our work begins to address questions associated with chirality, i.e., the origins of homochirality. On Earth, biological monomers (amino acids, sugars, etc.) are usually found with one of the enantiomers more abundant than the other. However, biological polymers (proteins, nucleic acids, etc.) are only composed of one enantiomer i.e., they are homochiral. There are hints in meteorites that some organic molecules may also exist in homochiral forms. The talk will address questions such as: did extraterrestrial sources aid in the beginning of this homochirality? Do the increasing size and apparent enantiomer excesses of some meteoritic compounds also extend to larger meteoritic compounds and polymers?

  13. The origin of power-law distributions in self-organized criticality

    International Nuclear Information System (INIS)

    Yang, C B

    2004-01-01

    The origin of power-law distributions in self-organized criticality is investigated by treating the variation of the number of active sites in the system as a stochastic process. An avalanche is then regarded as a first-return random-walk process in a one-dimensional lattice. Power-law distributions of the lifetime and spatial size are found when the random walk is unbiased with equal probability to move in opposite directions. This shows that power-law distributions in self-organized criticality may be caused by the balance of competitive interactions. At the mean time, the mean spatial size for avalanches with the same lifetime is found to increase in a power law with the lifetime. (letter to the editor)

  14. On Origin of Power-Law Distributions in Self-Organized Criticality from Random Walk Treatment

    International Nuclear Information System (INIS)

    Cao Xiaofeng; Deng Zongwei; Yang Chunbin

    2008-01-01

    The origin of power-law distributions in self-organized criticality is investigated by treating the variation of the number of active sites in the system as a stochastic process. An avalanche is then regarded as a first-return random walk process in a one-dimensional lattice. We assume that the variation of the number of active sites has three possibilities in each update: to increase by 1 with probability f 1 , to decrease by 1 with probability f 2 , or remain unchanged with probability 1-f 1 -f 2 . This mimics the dynamics in the system. Power-law distributions of the lifetime are found when the random walk is unbiased with equal probability to move in opposite directions. This shows that power-law distributions in self-organized criticality may be caused by the balance of competitive interactions.

  15. Development of Methods of Innovative Projects’ Management in Developer Organizations

    Directory of Open Access Journals (Sweden)

    Papelniuk Oksana

    2017-01-01

    Full Text Available In article the author studies the conceptual scheme of life cycle of innovative developer project and offers methods of innovative projects' management according to the stages of its lifecycle. The author describes algorithm of the organization of management system of innovative projects in the developer organization representing set of stages and methods. The offered algorithm allows developer organizations achieve one of the main of their objectives, which is the creation of a special environment of comfortable accommodation with the emphasis on ecological compatibility and energy efficiency.

  16. Organic agriculture in a development policy perspective

    DEFF Research Database (Denmark)

    Egelyng, Henrik; Halberg, Niels; Jensen, Henning Høgh

    Farmers growing food with high eco-efficiency may be seen cultivating peace by reducing competition among nations for oil and as producers of other public goods: biodiverse landscapes and ecosystem services with more soil fertility, less water use and less pollution. How does Organic agriculture...... (OA) fare globally on eco-efficiency? Are most African farmers eco-efficient – or may eco-efficient farmers be found everywhere? As OA develops throughout the planet, what does Denmark do beyond Europe? Is organic farming part of our development policy? Do we dilligently share our comparative...

  17. Using fluorescent dissolved organic matter to trace and distinguish the origin of Arctic surface waters

    Science.gov (United States)

    Gonçalves-Araujo, Rafael; Granskog, Mats A.; Bracher, Astrid; Azetsu-Scott, Kumiko; Dodd, Paul A.; Stedmon, Colin A.

    2016-01-01

    Climate change affects the Arctic with regards to permafrost thaw, sea-ice melt, alterations to the freshwater budget and increased export of terrestrial material to the Arctic Ocean. The Fram and Davis Straits represent the major gateways connecting the Arctic and Atlantic. Oceanographic surveys were performed in the Fram and Davis Straits, and on the east Greenland Shelf (EGS), in late summer 2012/2013. Meteoric (fmw), sea-ice melt, Atlantic and Pacific water fractions were determined and the fluorescence properties of dissolved organic matter (FDOM) were characterized. In Fram Strait and EGS, a robust correlation between visible wavelength fluorescence and fmw was apparent, suggesting it as a reliable tracer of polar waters. However, a pattern was observed which linked the organic matter characteristics to the origin of polar waters. At depth in Davis Strait, visible wavelength FDOM was correlated to apparent oxygen utilization (AOU) and traced deep-water DOM turnover. In surface waters FDOM characteristics could distinguish between surface waters from eastern (Atlantic + modified polar waters) and western (Canada-basin polar waters) Arctic sectors. The findings highlight the potential of designing in situ multi-channel DOM fluorometers to trace the freshwater origins and decipher water mass mixing dynamics in the region without laborious samples analyses. PMID:27667721

  18. Cloud Computing and Agile Organization Development

    Directory of Open Access Journals (Sweden)

    Bogdan GHILIC-MICU

    2014-01-01

    Full Text Available In the 3rd millennium economy, defined by globalization and continuous reduction of natural resources, the economic organization becomes the main actor in the phenomenon of transfor-mation and adaptation to new conditions. Even more, the economic environment, which is closely related to the social environment, undergoes complex metamorphoses, especially in the management area. In this dynamic and complex social and environmental context, the econom-ic organization must possess the ability to adapt, becoming a flexible and agile answer to new market opportunities. Considering the spectacular evolution of information and communica-tions technology, one of the solutions to ensure organization agility is cloud computing. Just like the development of any science requires adaptation to theories and instruments specific to other fields, a cloud computing paradigm for the agile organization must appeal to models from management, cybernetics, mathematics, structuralism and information theory (or information systems theory.

  19. Rules of origin and development of regional production network in ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Simpler Rules of Origin (RoO) with product specific rules can act as a catalyst in trade even if tariff rates are not low. Sector specific restrictiveness across trade agreements are assessed, in view of potential growth of International production networks (IPN). RoO is shown to play a significant role in promoting IPN.

  20. Volatile and intermediate volatility organic compounds in suburban Paris: variability, origin and importance for SOA formation

    International Nuclear Information System (INIS)

    Ait-Helal, W.; Borbon, A.; Beekmann, M.; Doussin, J.F.; Durand-Jolibois, R.; Grand, N.; Michoud, V.; Miet, K.; Perrier, S.; Siour, G.; Zapf, P.; Sauvage, S.; Fronval, I.; Leonardis, T.; Locoge, N.; Gouw, J.A. de; Colomb, A.; Gros, V.; Lopez, M.

    2014-01-01

    Measurements of gaseous and particulate organic carbon were performed during the MEGAPOLI experiments, in July 2009 and January-February 2010, at the SIRTA observatory in suburban Paris. Measurements comprise primary and secondary volatile organic compounds (VOCs), of both anthropogenic and biogenic origins, including C12-C16 n-alkanes of intermediate volatility (IVOCs), suspected to be efficient precursors of secondary organic aerosol (SOA). The time series of gaseous carbon are generally consistent with times series of particulate organic carbon at regional scale, and are clearly affected by meteorology and air mass origin. Concentration levels of anthropogenic VOCs in urban and suburban Paris were surprisingly low (2-963 ppt) compared to other mega-cities worldwide and to rural continental sites. Urban enhancement ratios of anthropogenic VOC pairs agree well between the urban and suburban Paris sites, showing the regional extent of anthropogenic sources of similar composition. Contrary to other primary anthropogenic VOCs (aromatics and alkanes), IVOCs showed lower concentrations in winter (≤ 5 ppt) compared to summer (13-27 ppt), which cannot be explained by the gas-particle partitioning theory. Higher concentrations of most oxygenated VOCs in winter (18-5984 ppt) suggest their dominant primary anthropogenic origin. The respective role of primary anthropogenic gaseous compounds in regional SOA formation was investigated by estimating the SOA mass concentration expected from the anthropogenic VOCs and IVOCs (I/VOCs) measured at SIRTA. From an integrated approach based on emission ratios and SOA yields, 38% of the SOA measured at SIRTA is explained by the measured concentrations of I/VOCs, with a 2% contribution by C12-C16 n-alkane IVOCs. From the results of an alternative time-resolved approach, the average IVOC contribution to SOA formation is estimated to be 7 %, which is half of the average contribution of the traditional aromatic compounds (15 %). Both

  1. Desenvolvimento de Órgãos da Digestão e Rendimento de Carcaça de Frangos de Corte de Diversas Origens Genéticas Criados com Bebedouros Pendular e Nipple Development of Digestive Organs and Carcass Yield of Broilers from Diverse Genetic Origin Raised with Regular or Nipple Drinkers

    Directory of Open Access Journals (Sweden)

    LM Fernandes

    2002-01-01

    broiler houses has increased in the last few years; however, practical benefits have not been proved yet. This study evaluated the development of the digestive organs, live performance and carcass and cut up yields from broilers originated of the crossing between breeder males from four commercial strains (R, I, S, and H with females also from various origins (R, I, and H raised in pens with bell or nipple drinkers. Birds’ growth curves varied with strain cross and led to better body weight at marketing for the RR strain cross. Breast yield, however, was better for the cross IH. The SH strain cross showed a consistently lower body weight and carcass yield at all ages. The type of drinker did not affect any measured response regardless of the strain cross. Strain crosses or type of drinkers did not affect development of the digestive organs.

  2. Endogenous production, exogenous delivery and impact-shock synthesis of organic molecules - An inventory for the origins of life

    Science.gov (United States)

    Chyba, Christopher; Sagan, Carl

    1992-01-01

    The contribution of organic-rich comets, carbonaceous asteroids, and interplanetary dust particles and of impact shock-synthesized organics in the atmosphere to the origin of life on earth is studied and quantitatively compared with the principal non-heavy-bombardment sources of prebiotic organics. The results suggest that heavy bombardment before 3.5 Gyr ago either produced or delivered quantities of organics comparable to those produced by other energy sources.

  3. Origin and variability in volatile organic compounds observed at an Eastern Mediterranean background site (Cyprus)

    Science.gov (United States)

    Debevec, Cécile; Sauvage, Stéphane; Gros, Valérie; Sciare, Jean; Pikridas, Michael; Stavroulas, Iasonas; Salameh, Thérèse; Leonardis, Thierry; Gaudion, Vincent; Depelchin, Laurence; Fronval, Isabelle; Sarda-Esteve, Roland; Baisnée, Dominique; Bonsang, Bernard; Savvides, Chrysanthos; Vrekoussis, Mihalis; Locoge, Nadine

    2017-09-01

    More than 7000 atmospheric measurements of over 60 C2 - C16 volatile organic compounds (VOCs) were conducted at a background site in Cyprus during a 1-month intensive field campaign held in March 2015. This exhaustive dataset consisted of primary anthropogenic and biogenic VOCs, including a wide range of source-specific tracers, and oxygenated VOCs (with various origins) that were measured online by flame ionization detection-gas chromatography and proton transfer mass spectrometry. Online submicron aerosol chemical composition was performed in parallel using an aerosol mass spectrometer. This study presents the high temporal variability in VOCs and their associated sources. A preliminary analysis of their time series was performed on the basis of independent tracers (NO, CO, black carbon), meteorological data and the clustering of air mass trajectories. Biogenic compounds were mainly attributed to a local origin and showed compound-specific diurnal cycles such as a daily maximum for isoprene and a nighttime maximum for monoterpenes. Anthropogenic VOCs as well as oxygenated VOCs displayed higher mixing ratios under the influence of continental air masses (i.e., western Asia), indicating that long-range transport significantly contributed to the VOC levels in the area. Source apportionment was then conducted on a database of 20 VOCs (or grouped VOCs) using a source receptor model. The positive matrix factorization and concentration field analyses were hence conducted to identify and characterize covariation factors of VOCs that were representative of primary emissions as well as chemical transformation processes. A six-factor PMF solution was selected, namely two primary biogenic factors (relative contribution of 43 % to the total mass of VOCs) for different types of emitting vegetation; three anthropogenic factors (short-lived combustion source, evaporative sources, industrial and evaporative sources; 21 % all together), identified as being either of local origin

  4. Origin of Titan’s Nitrogen: Contributions from Organics in the Core

    Science.gov (United States)

    Miller, Kelly E.; Glein, Christopher R.; Waite, J. Hunter

    2017-10-01

    The origin of Titan’s atmosphere has been a puzzle for decades. The major atmospheric component is N2, with a 14N/15N ratio of ~168. This ratio is enriched in heavy N compared to the solar ratio of 441, but is similar to that measured in cometary comae for NH2 (127), a product of NH3 in the coma. These data have been used to argue that Titan’s nitrogen was accreted as NH3, and converted through shock or photochemical processes to N2. This model assumes that N2 and NH3 were the only major reservoirs of nitrogen in the early solar system. To test this model, further constraints on the building blocks of Titan are needed.Comets are thought to preserve the best records of the materials accreted to form outer solar system bodies. Measurements of Halley revealed the presence of an abundant refractory organic component coating cometary dust grains. The organic component constituted ~50 wt.% of the dust. This component has since been detected at other comets by later missions, including Deep Impact and most recently the Rosetta mission. Multiple instruments on Rosetta have converged on a dust-to-ice mass ratio at 67P/Churyumov-Gerasimenko between 1 and 4, suggesting that refractory materials are a significant component. Data from the Cometary Secondary Ion Mass Analyser (COSIMA) confirm that this refractory material includes abundant organics, with a bulk composition similar to insoluble organic matter (IOM) in chondrites. These data suggest that 67P is composed of ~25 wt.% refractory organics. Using these constraints from Rosetta and IOM as an analog material, we find via mass balance calculations that organic N represents a third major reservoir of nitrogen in the early solar system. This third reservoir could have been a source material for Titan’s atmosphere.We present a cosmochemical model for Titan’s atmosphere that incorporates this third reservoir via heating in a rocky core. We deduce the relative contributions of N2, NH3, and organic N to Titan

  5. Removal of organic compounds from wastewater originating from the production of printed circuit boards by UV-Fenton method

    Directory of Open Access Journals (Sweden)

    Thomas Maciej

    2017-12-01

    Full Text Available The possibility of removing organic compounds from wastewater originating from the photochemical production of printed circuit boards by use of waste acidification and disposal of precipitated photopolymer in the first stage and the UV-Fenton method in a second stage has been presented. To optimize the process of advanced oxidation, the RSM (Response Surface Methodology for three independent factors was applied, i.e. pH, the concentration of Fe(II and H2O2 concentration. The use of optimized values of individual parameters in the process of wastewater treatment caused a decrease in the concentration of the organic compounds denoted as COD by approx. 87% in the first stage and approx. 98% after application of both processes. Precipitation and the decomposition of organic compounds was associated with a decrease of wastewater COD to below 100 mg O2/L whereas the initial value was 5550 mg O2/L. Decomposition of organic compounds and verification of the developed model of photopolymers removal was also carried out with use of alternative H2O2 sources i.e. CaO2, MgO2, and Na2CO3·1,5H2O2.

  6. DEVELOPING A VIRTUAL ORGANIZATION: SERENDIPITY OR STRATEGY?

    Directory of Open Access Journals (Sweden)

    Shirley Gregor

    2002-01-01

    Full Text Available This paper addresses the question of how virtual organizations that yield strategic advantage are formed. The study uses grounded theory to investigate the organizational processes and structure that facilitate the formation of a successful virtual organization. We present a case study of one virtual organization, a university in Australia, which has gained strategic advantage from alliances supported by information and communication technologies (ICT. The university is now the fastest growing university in Australia in terms of international student enrolments. The case study suggests that this commercial success is based on responsiveness to environmental conditions and organizational factors that include a long history as a distance education provider (an early form of virtualization, sophisticated information communication technologies, and a culture of innovation and risk-taking. The development processes observed included evolutionary growth, decisive actions and management leadership at opportune moments, and examples of technological and entrepreneurial innovations led by individuals. Significant decision making occurred outside formal strategic planning processes.

  7. Lessons for Staff Developers from an Organization Development Intervention.

    Science.gov (United States)

    Conway, James A.

    1990-01-01

    A case study of an organization development intervention in a large New York State school district describes to staff developers the complex process of discovering and responding to organizational needs. The discussion focuses on understanding the problem; frameworks for diagnosis and intervention; and implementing the intervention strategy.…

  8. On the Origin and Development of the Medical Nutrition Industry

    NARCIS (Netherlands)

    T.C. Weenen (Tamar)

    2014-01-01

    markdownabstract__Abstract__ Product development in the health and life sciences is shifting from the development of target-specific pharmaceutical products to multi-target therapies, including medical nutrition. Medical nutrition consists of nutritional compositions, prescribed by medical

  9. Food allergies developing after solid organ transplant.

    Science.gov (United States)

    Needham, J M; Nicholas, S K; Davis, C M

    2015-12-01

    The development of food allergy is an increasingly recognized form of morbidity after solid organ transplant. It occurs more commonly in liver transplant recipients, although it has also been reported in heart, lung, kidney, and intestinal transplants. Pediatric transplant recipients are more likely to develop symptoms compared to adults, and reports of frequency vary widely from 5% to 38% in pediatric liver transplant recipients. Multiple mechanisms have been proposed in the literature, although no single mechanism can yet account for all reported observations. As food allergy can have at worst potentially fatal consequences, and at best require lifestyle adjustment through food avoidance, it is important for recipients to be aware of the donor's food allergies and particularly in pediatrics, the possibility of completely de novo allergies. This review explores the recent reports surrounding food allergy after solid organ transplant, including epidemiology, proposed mechanisms, and implications for practice. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. Home economics: origin, development and professional working field

    Directory of Open Access Journals (Sweden)

    Ana Carla Menezes de Oliveira

    2010-05-01

    Full Text Available Home Economics is not only a set of practical knowledge housewives must possess to prepare food empirically, make and repair clothes, take care of their children and do domestic chores. The objective of this article is to discuss the area of Economics defined as Home Economics, focusing on its origin, evolution, the working field of its specialists and its prospects for the 21st century. Results show the need for scientific and professional knowledge of Home Economics in schools, families and society. The study of Home Economics is of great importance because both school and family are part of society and present very complex phenomena, therefore an adequate and efficient solution for those phenomena demand the knowledge of specialized scientific notions of Home Economics.

  11. Primary and secondary organic aerosol origin by combined gas-particle phase source apportionment

    Directory of Open Access Journals (Sweden)

    M. Crippa

    2013-08-01

    Full Text Available Secondary organic aerosol (SOA, a prominent fraction of particulate organic mass (OA, remains poorly constrained. Its formation involves several unknown precursors, formation and evolution pathways and multiple natural and anthropogenic sources. Here a combined gas-particle phase source apportionment is applied to wintertime and summertime data collected in the megacity of Paris in order to investigate SOA origin during both seasons. This was possible by combining the information provided by an aerosol mass spectrometer (AMS and a proton transfer reaction mass spectrometer (PTR-MS. A better constrained apportionment of primary OA (POA sources is also achieved using this methodology, making use of gas-phase tracers. These tracers made possible the discrimination between biogenic and continental/anthropogenic sources of SOA. We found that continental SOA was dominant during both seasons (24–50% of total OA, while contributions from photochemistry-driven SOA (9% of total OA and marine emissions (13% of total OA were also observed during summertime. A semi-volatile nighttime component was also identified (up to 18% of total OA during wintertime. This approach was successfully applied here and implemented in a new source apportionment toolkit.

  12. Development of organic MRI contrast agents

    International Nuclear Information System (INIS)

    Hayashi, Hiroyuki; Sato, Yuichiro; Karasawa, Satoru; Koga, Noboru

    2008-01-01

    Described are trends of the development in the title since those agents with target properties are awaited for specific organ and regional MRI. The contrast agents alter the relaxation time of water proton to yield the enhanced contrast between organs and tissues with different water volumes. Nowadays Gd-complexes and nano-particle of superparamagnetic iron oxide (Fe(III)) are widely used for enhancing in clinic. Among organic compounds with paramagnetic spin, those possessing nitroxide radical like TEMPO- and PROXYL-radicals have been subject to development by their derivatization. High spin molecules conceivably affect the relaxivity, which, however, is found smaller per spin of synthesized triplet complexes than doublet ones. This has lead to basic approach for molecules restricting water movement due to their hydrogen bond like DNA as a model, for introducing many radicals in high molecular weight compounds, and their polymer, as one of which authors have developed a derivative of hyperbranched polymer (HPS)-TEMPO having the similar relaxivity to gadolinium-diethylenetiamine pentaacetid acid (Gd-DTPA) (R.T.)

  13. Assessing the origin of unusual organic formations in lava caves from Canary Islands (Spain)

    Science.gov (United States)

    Miller, Ana Z.; de la Rosa, Jose M.; Garcia-Sanchez, Angela M.; Pereira, Manuel F. C.; Jurado, Valme; Fernández, Octavio; Knicker, Heike; Saiz-Jimenez, Cesareo

    2016-04-01

    Lava tubes, like other caves, contain a variety of speleothems formed in the initial stage of a lava tube formation or due to leaching and subsequent precipitation of secondary minerals. Primary and secondary mineral formations in lava caves are mainly composed of silicate minerals, although secondary minerals common in limestone caves have been also reported in this type of caves. In addition, unusual colored deposits have been found on the walls and ceilings of lava tubes, some of them of unknown origin and composition. A brown to black-colored mud-like deposits was observed in "Llano de los Caños" Cave, La Palma Island, Canary Islands, Spain. These black deposits coat the wall and ceiling of the lava tube where sub-horizontal fractures occur. FESEM-EDS, X-ray micro-computed tomography and mineralogical analyses were conducted for morphological, 3D microstructural and compositional characterization of these unusual speleothem samples. These techniques revealed that they are mainly composed of amorphous materials, suggesting an organic carbon composition. Hence, analytical pyrolysis (Py-GC/MS), solid-state 13C Nuclear Magnetic Resonance (NMR) and stable isotope analysis were applied to assess the nature and origin of the black deposits. The combination of these analytical tools permits the identification of specific biomarkers (di- and triterpenoids) for tracing the potential sources of the organic compounds in the speleothems. For comparison purposes, samples from the topsoil and overlaying vegetation were also analyzed. Chromatograms resulting from the Py-GC/MS showed an abundance of polysaccharides, lipids and terpenoids typically derived from the vegetation of the area (Erica arborea). In addition, levoglucosan, polycyclic aromatic hydrocarbons and N-containing heterocyclic compounds were detected. They probably derived from the leaching of charred vegetation resulting from a wildfire occurred in the area in 2012. The lack of the typical pattern of odd

  14. Dual odontogenic origins develop at the early stage of rat maxillary incisor development.

    Science.gov (United States)

    Kriangkrai, Rungarun; Iseki, Sachiko; Eto, Kazuhiro; Chareonvit, Suconta

    2006-03-01

    Developmental process of rat maxillary incisor has been studied through histological analysis and investigation of tooth-related gene expression patterns at initial tooth development. The tooth-related genes studied here are fibroblast growth factor-8 (Fgf-8), pituitary homeobox gene-2 (Pitx-2), sonic hedgehog (Shh), muscle segment homeobox-1 (Msx-1), paired box-9 (Pax-9) and bone morphogenetic protein-4 (Bmp-4). The genes are expressed in oral epithelium and/or ectomesenchyme at the stage of epithelial thickening to the early bud stage of tooth development. Both the histological observation and tooth-related gene expression patterns during early stage of maxillary incisor development demonstrate that dual odontogenic origins aligned medio-laterally in the medial nasal process develop, subsequently only single functional maxillary incisor dental placode forms. The cascade of tooth-related gene expression patterns in rat maxillary incisor studied here is quite similar to those of the previous studies in mouse mandibular molar, even though the origins of oral epithelium and ectomesenchyme involved in development of maxillary incisor and mandibular molar are different. Thus, we conclude that maxillary incisor and mandibular molar share a similar signaling control of Fgf-8, Pitx-2, Shh, Msx-1, Pax-9 and Bmp-4 genes at the stage of oral epithelial thickening to the early bud stage of tooth development.

  15. Bioavailability of dissolved organic matter originating from different sources in the River Vantaa

    Science.gov (United States)

    Hoikkala, Laura; Soinne, Helena; Asmala, Eero; Helin, Janne; Autio, Iida; Rahikainen, Mika

    2013-04-01

    Most of the dissolved organic matter (DOM) pool in the Baltic Sea is of terrestrial origin. Organic matter load to the Baltic Sea has been identified as the second greatest environmental pressure both in the Bothnian Bay and in the Gulf of Finland by the HELCOM Holistic Assessment. Loads of terrestrial DOM may increase the productivity, oxygen consumption and light attenuation in the coastal waters. The quantity and quality of DOM loads that enter the Baltic Sea depend on the properties of the catchment area, land use and the runoff as well as ecological processes and water retention time in freshwater systems, and are sensitive to temperature. In this study we investigate DOM loads from River Vantaa, which has a catchment area of 1 685 km2 and flows through the most important population center in Southern Finland into the Gulf of Finland. We focus on the effects of soil type and land-use on the DOM load and on the bioavailability of DOM to bacteria in the Baltic Sea. In addition, samples will be collected from up- and downstream of main water treatment plants to estimate the effect of municipal waste on the DOM loads. Further, we aim to estimate the total DOM loads to the Baltic Sea from samples taken at the river mouth. Water samples are collected from river branches selected according to the main land-use (forest or agricultural land) and soil type (mineral or organic soil) in the catchment area. The DOC, DON and DOP loads will be measured. The bioavailability of DOC is measured by incubating the DOM samples (<0.2 µm) in nutrient replete conditions with bacterial inocula (<0.8 µm, retentate of 100 kD TFF) from either river mouth or the Gulf of Finland for two months at dark. Time courses of DOC and DON concentrations, CDOM absorption and fluorescence, bacterial biomass and respiration will be followed.

  16. Secondary organic aerosol origin in an urban environment: influence of biogenic and fuel combustion precursors.

    Science.gov (United States)

    Minguillón, M C; Pérez, N; Marchand, N; Bertrand, A; Temime-Roussel, B; Agrios, K; Szidat, S; van Drooge, B; Sylvestre, A; Alastuey, A; Reche, C; Ripoll, A; Marco, E; Grimalt, J O; Querol, X

    2016-07-18

    Source contributions of organic aerosol (OA) are still not fully understood, especially in terms of quantitative distinction between secondary OA formed from anthropogenic precursors vs. that formed from natural precursors. In order to investigate the OA origin, a field campaign was carried out in Barcelona in summer 2013, including two periods characterized by low and high traffic conditions. Volatile organic compound (VOC) concentrations were higher during the second period, especially aromatic hydrocarbons related to traffic emissions, which showed a marked daily cycle peaking during traffic rush hours, similarly to black carbon (BC) concentrations. Biogenic VOC (BVOC) concentrations showed only minor changes from the low to the high traffic period, and their intra-day variability was related to temperature and solar radiation cycles, although a decrease was observed for monoterpenes during the day. The organic carbon (OC) concentrations increased from the first to the second period, and the fraction of non-fossil OC as determined by (14)C analysis increased from 43% to 54% of the total OC. The combination of (14)C analysis and Aerosol Chemical Speciation Monitor (ACSM) OA source apportionment showed that the fossil OC was mainly secondary (>70%) except for the last sample, when the fossil secondary OC only represented 51% of the total fossil OC. The fraction of non-fossil secondary OC increased from 37% of total secondary OC for the first sample to 60% for the last sample. This enhanced formation of non-fossil secondary OA (SOA) could be attributed to the reaction of BVOC precursors with NOx emitted from road traffic (or from its nocturnal derivative nitrate that enhances night-time semi-volatile oxygenated OA (SV-OOA)), since NO2 concentrations increased from 19 to 42 μg m(-3) from the first to the last sample.

  17. Passive Signals from Aggressive Methods: The Origin and Implications of Organic Material in a Carbonate Stromatolite

    Science.gov (United States)

    Petryshyn, V.; Bailey, J.; Stamps, B. W.; Stevenson, B. S.; Corsetti, F. A.

    2017-12-01

    Microbial activity can play a role in the construction of carbonate features like stromatolites and thrombolites, but determining whether microbes were directly or indirectly involved in the formation can be difficult—an endeavor that becomes more difficult as geologic time passes and organic signals degrade. In order to assess our ability to decipher the role of microbes in stromatolite formation, DNA (geologically short-lived) and alkanes (potentially geologically long-lived) were extracted and analyzed from finely-laminated Holocene carbonate stromatolites of Walker Lake, Nevada. The stromatolitic laminations were typically between 50 and 100 microns thick. The surrounding sediment and lake water was also sampled, for comparison. SSU rRNA gene sequencing suggests that a large percentage (25-40 % relative abundance) of the microbial community found within the stromatolite is comprised of ambient lake algae, not known to form stromatolite-building mats given their size vs. stromatolite lamination thickness, rather than the usual taxa associated with the formation of stromatolites. Other minor taxa were identified, including the bacterial families Cyanobacteria, Flavobacteriaceae, and Rhodobacteraceae. Mirroring the DNA results, the carbon isotopic compositions of the alkanes were largely indistinguishable from the limnic biomass dominated by lake algae. The results suggest that organic matter was passively incorporated into the carbonate structure from the lake as it accreted. Although evidence of life was abundant in the stromatolite, a direct role (builders) or even an indirect role (tenants) is difficult to establish, as the 16S/18S and lipid biomarkers appear to simply originate from the water column (squatters) and not from a unique microbial mat. In the absence of in situ analyses during the formation of the stromatolite, it may be difficult to disentangle the builders from the tenants and/or squatters based solely on molecular or organic geochemical data

  18. Transdisciplinarity: A Review of Its Origins, Development, and Current Issues

    Directory of Open Access Journals (Sweden)

    Jay Hillel Bernstein

    2015-07-01

    Full Text Available Transdisciplinarity originated in a critique of the standard configuration of knowledge in disciplines in the curriculum, including moral and ethical concerns. Pronouncements about it were first voiced between the climax of government-supported science and higher education and the long retrenchment that began in the 1970s. Early work focused on questions of epistemology and the planning of future universities and educational programs. After a lull, transdisciplinarity re-emerged in the 1990s as an urgent issue relating to the solution of new, highly complex, global concerns, beginning with climate change and sustainability and extending into many areas concerning science, technology, social problems and policy, education, and the arts. Transdisciplinarity today is characterized by its focus on “wicked problems” that need creative solutions, its reliance on stakeholder involvement, and engaged, socially responsible science. In simultaneously studying multiple levels of, and angles on, reality, transdisciplinary work provides an intriguing potential to invigorate scholarly and scientific inquiry both in and outside the academy.

  19. Review of History and Recent Development of Organic Farming Worldwide

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The history of the organic farming worldwide was reviewed in this paper. The development of the organic farming worldwide had gone through three stages, emergence, expansion, and growth. The contributors and their thoughts during the different development stages of the organic farming were briefly introduced. And the development status of the organic farming worldwide was reviewed from the aspects of land area under organic management, land area under organic management in percentage of total agricultural area, and world markets for organic products. Besides, the main existing problems for the further development of the world's organic farming, as well as the development status, problems and strategies of the Chinese organic farming were discussed.

  20. Origin and variability in volatile organic compounds observed at an Eastern Mediterranean background site (Cyprus

    Directory of Open Access Journals (Sweden)

    C. Debevec

    2017-09-01

    Full Text Available More than 7000 atmospheric measurements of over 60 C2 − C16 volatile organic compounds (VOCs were conducted at a background site in Cyprus during a 1-month intensive field campaign held in March 2015. This exhaustive dataset consisted of primary anthropogenic and biogenic VOCs, including a wide range of source-specific tracers, and oxygenated VOCs (with various origins that were measured online by flame ionization detection–gas chromatography and proton transfer mass spectrometry. Online submicron aerosol chemical composition was performed in parallel using an aerosol mass spectrometer. This study presents the high temporal variability in VOCs and their associated sources. A preliminary analysis of their time series was performed on the basis of independent tracers (NO, CO, black carbon, meteorological data and the clustering of air mass trajectories. Biogenic compounds were mainly attributed to a local origin and showed compound-specific diurnal cycles such as a daily maximum for isoprene and a nighttime maximum for monoterpenes. Anthropogenic VOCs as well as oxygenated VOCs displayed higher mixing ratios under the influence of continental air masses (i.e., western Asia, indicating that long-range transport significantly contributed to the VOC levels in the area. Source apportionment was then conducted on a database of 20 VOCs (or grouped VOCs using a source receptor model. The positive matrix factorization and concentration field analyses were hence conducted to identify and characterize covariation factors of VOCs that were representative of primary emissions as well as chemical transformation processes. A six-factor PMF solution was selected, namely two primary biogenic factors (relative contribution of 43 % to the total mass of VOCs for different types of emitting vegetation; three anthropogenic factors (short-lived combustion source, evaporative sources, industrial and evaporative sources; 21 % all together, identified

  1. Organizing the HIV vaccine development effort.

    Science.gov (United States)

    Voronin, Yegor; Snow, William

    2013-09-01

    To describe and compare the diverse organizational structures and funding mechanisms applied to advance HIV preventive vaccine research and development and to help explain and inform evolving infrastructures and collaborative funding models. On the basis of models that have been tried, improved or abandoned over three decades, the field seems to have settled into a relatively stable set of diverse initiatives, each with its own organizational signature. At the same time, this set of organizations is forging cross-organizational collaborations, which promise to acquire newly emergent beneficial properties. Strong motivation to expedite HIV vaccine R&D has driven a diversity of customized and inventive organizational approaches, largely government and foundation funded. Although no one approach has proven a panacea, the field has evolved into a constellation of often overlapping organizations that complement or reinforce one another. The Global HIV Vaccine Enterprise, a responsive, rapidly evolving loose infrastructure, is an innovative collaboration to catalyze that evolution.

  2. Origins of terrestrial organic matter in surface sediments of the East China Sea shelf

    Science.gov (United States)

    Zhang, Hailong; Xing, Lei; Zhao, Meixun

    2017-10-01

    Terrestrial organic matter (TOM) is an important component of marine sedimentary OM, and revealing the origins and transport mechanisms of TOM to the East China Sea (ECS) is important for understanding regional carbon cycle. A novel approach combining molecular proxies and compound-specific carbon isotopes is used to quantitatively constrain the origins and transport mechanisms of TOM in surface sediments from the ECS shelf. The content of terrestrial biomarkers of (C27+C29+C31) n-alkanes (52 to 580 ng g-1) revealed a seaward decreasing trend, the δ13CTOC values (-20.6‰ to -22.7‰) were more negative near the coast, and the TMBR (terrestrial and marine biomarker ratio) values (0.06 to 0.40) also revealed a seaward decreasing trend. These proxies all indicated more TOM (up to 48%) deposition in the coastal areas. The Alkane Index, the ratio of C29/(C29+C31) n-alkanes indicated a higher proportion of grass vegetation in the coastal area; While the δ13C values of C29 n-alkane (-29.3‰ to -33.8‰) indicated that terrestrial plant in the sediments of the ECS shelf were mainly derived from C3 plants. Cluster analysis afforded detailed estimates of different-sourced TOM contributions and transport mechanisms. TOM in the Zhejiang-Fujian coastal area was mostly delivered by the Changjiang River, and characterized by higher %TOM (up to 48%), higher %C3 plant OM (68%-85%) and higher grass plant OM (56%-61%); TOM in the mid-shelf area was mostly transported by aerosols, and characterized by low %TOM (less than 17%), slightly lower C3 plant OM (56%-72%) and lower grass plant OM (49%-55%).

  3. Nature, Origin and Transfers of SPM (Mineral, Organic, and Biological) in Hydrosystems : a New Methodological Approach by Morphogranulometry

    Science.gov (United States)

    Viennet, D.; Fournier, M.; Copard, Y.; Dupont, J. P.

    2017-12-01

    Source to sink is one of the main concepts in Earth Sciences for a better knowledge of hydrosystems dynamics. Regarding this issue, the present day challenge consists in the characterization by in-situ measurements of the nature and the origin of suspended particles matters (SPM). Few methods can fully cover such requirements and among them, the methodology using the form of particles deserves to be developed. Indeed, morphometry of particles is widely used in sedimentology to identify different sedimentary stocks, source-to-sink transport and sedimentation mechanisms. Currently, morphometry analyses are carried out by scanning electron microscope coupled to image analysis to measure various size and shape descriptors on particles like flatness, elongation, circularity, sphericity, bluntness, fractal dimension. However, complexity and time of analysis are the main limitations of this technique for a long-term monitoring of SPM transfers. Here we present an experimental morphometric approach using a morphogranulometer (a CCD camera coupled to a peristaltic pump). The camera takes pictures while the sample is circulating through a flow cell, leading to the analysis of numerous particles in a short time. The image analysis provides size and shape information discriminating various particles stocks according to their nature and origin by statistical analyses. Measurements were carried out on standard samples of particles commonly found in natural waters. The size and morphological distributions of the different mineral fractions (clay, sand, oxides etc), biologic (microalgae, pollen, etc) and organic (peat, coal, soil organic matter, etc) samples are statistically independent and can be discriminated on a 4D graph. Next step will be on field in situ measurements in a sink-spring network to understand the transfers of the particles stocks inside this simple karstic network. Such a development would be promising for the characterisation of natural hydrosystems.

  4. IVF and embryo transfer: historical origin and development.

    Science.gov (United States)

    Biggers, John D

    2012-08-01

    IVF and embryo transfer for the treatment of human infertility has now resulted in the birth of over 4 million babies. The technique did not arise as a quantum event but was built on the efforts of many earlier workers in the fields of reproductive endocrinology and development. One should remember the famous saying of Isaac Newton: 'If I have seen further than most, it is because I have stood on the shoulder's of giants'. Ethical and moral issues have always arisen when investigators study early mammalian development, particularly human development. This paper documents these earlier studies and also draws attention to the ethical and moral arguments that inevitably arose. Copyright © 2012 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  5. Origins of Social Security in Developing Countries: the Case of ...

    African Journals Online (AJOL)

    ... arrangements or schemes have developed in the way they have, nor has there been an in depth analysis of the structure of the current institutions, the range and scope of covers, as well as the process of benefit delivery. The paper attempts such a study. African Journal of Finance and Management Vol.7(1) 1998: 61-68 ...

  6. Community Psychology in South Africa: Origins, Developments, and Manifestations

    Science.gov (United States)

    Seedat, Mohamed; Lazarus, Sandy

    2011-01-01

    This article represents a South African contribution to the growing international body of knowledge on histories of community psychology. We trace the early antecedents of social-community psychology interventions and describe the social forces and academic influences that provided the impetus for the emergence and development of community…

  7. THE ORIGIN AND DEVELOPMENT OF JUJU MUSIC: 1900-1990 ...

    African Journals Online (AJOL)

    imitch

    Nigerian popular music was largely neglected and many key areas such as its history remained unaddressed ... development of juju from its early beginnings in the early 1900s to when it ..... The relationship between sound and movement was exploited by Juju musicians realizing that their fame .... is not a load fit for a child.

  8. Origins and Hallmarks of Macrophages: Development, Homeostasis, and Disease

    Science.gov (United States)

    Wynn, Thomas A.; Chawla, Ajay; Pollard, Jeffrey W.

    2013-01-01

    Preface Macrophages the most plastic cells of the hematopoietic system are found in all tissues and exhibit great functional diversity. They have roles in development, homeostasis, tissue repair, and immunity. While anatomically distinct, resident tissue macrophages exhibit different transcriptional profiles, and functional capabilities, they are all required for the maintenance of homeostasis. However, these reparative and homeostatic functions can be subverted by chronic insults, resulting in a causal association of macrophages with disease states. In this review, we discuss how macrophages regulate normal physiology and development and provide several examples of their pathophysiologic roles in disease. We define the “hallmarks” of macrophages performing particular functions, taking into account novel insights into the diversity of their lineages, identity, and regulation. This diversity is essential to understand because macrophages have emerged as important therapeutic targets in many important human diseases. PMID:23619691

  9. Origin, development, and evolution of eye movement desensitization and reprocessing

    Directory of Open Access Journals (Sweden)

    Carolina Marín

    2016-12-01

    Full Text Available Eye movement desensitization and reprocessing (EMDR has led to a great number of studies since its appearance in 1989. The aim of this article is to describe EMDR development and evolution to the present day. With this purpose a search was carried out on MEDLINE and PsycINFO with the entry "eye movement desensitization". After revising the resulting 797 articles, those that because of their relevance explained best the development and evolution of the technique were chosen and shaped into a lifeline graphically representing the history of EMDR. Despite the fact that during the first years the focus of research was on the validation of the technique for post-traumatic disorder (PTSD, it was soon applied to other areas. Only 14% of the articles found account for controlled studies. Up to date, in spite of the effectiveness of EMDR for the treatment of PTSD that has been proven, many different explanatory hypotheses are still up for discussion.

  10. Self-Organization in Integrated Conservation and Development Initiatives

    Directory of Open Access Journals (Sweden)

    Cristiana Simão Seixas

    2007-11-01

    Full Text Available This paper uses a cooking metaphor to explore key elements (i.e., ingredients for a great meal that contribute to self-organization processes in the context of successful community-based conservation (CBC or integrated conservation and development projects (ICDP. We pose two major questions: (1 What are the key factors that drive peoples' and/or organizations' willingness to take responsibilities and to act? (2 What contributes to community self-organization? In other words, how conservation-development projects originate, evolve, survive or disappear? In order to address these questions we examine trigger events and catalytic elements in several cases among the Equator Prize finalists and short-listed nominees, from both the 2002 and 2004 awards. The Prize recognizes efforts in integrating biodiversity conservation and poverty reduction. We use secondary data in our analysis, including data from several technical reports and scientific papers written about the Equator Prize finalists and short-listed nominees. We observed common ingredients in most projects including: (1 involvement and commitment of key players (including communities, (2 funding, (3 strong leadership, (4 capacity building, (5 partnership with supportive organizations and government, and (6 economic incentives (including alternative livelihood options. We also observed that CBC and ICDP initiatives opportunistically evolve in a multi-level world, in which local communities establish linkages with people and organizations at different political levels, across different geographical scales and for different purposes. We conclude that there is no right 'recipe' to promote community self-organization but often a mix of some of these six ingredients need to come together for 'success' and that one or two ingredients are not sufficient to ensure success. Also the existence of these six ingredients does not guarantee a great meal - the 'chef's' creativity also is critical. That is

  11. World Health Organization guideline development: an evaluation.

    Directory of Open Access Journals (Sweden)

    David Sinclair

    Full Text Available BACKGROUND: Research in 2007 showed that World Health Organization (WHO recommendations were largely based on expert opinion, rarely used systematic evidence-based methods, and did not follow the organization's own "Guidelines for Guidelines". In response, the WHO established a "Guidelines Review Committee" (GRC to implement and oversee internationally recognized standards. We examined the impact of these changes on WHO guideline documents and explored senior staff's perceptions of the new procedures. METHODS AND FINDINGS: We used the AGREE II guideline appraisal tool to appraise ten GRC-approved guidelines from nine WHO departments, and ten pre-GRC guidelines matched by department and topic. We interviewed 20 senior staff across 16 departments and analyzed the transcripts using the framework approach. Average AGREE II scores for GRC-approved guidelines were higher across all six AGREE domains compared with pre-GRC guidelines. The biggest changes were noted for "Rigour of Development" (up 37.6%, from 30.7% to 68.3% and "Editorial Independence" (up 52.7%, from 20.9% to 73.6%. Four main themes emerged from the interviews: (1 high standards were widely recognized as essential for WHO credibility, particularly with regard to conflicts of interest; (2 views were mixed on whether WHO needed a single quality assurance mechanism, with some departments purposefully bypassing the procedures; (3 staff expressed some uncertainties in applying the GRADE approach, with departmental staff concentrating on technicalities while the GRC remained concerned the underlying principles were not fully institutionalized; (4 the capacity to implement the new standards varied widely, with many departments looking to an overstretched GRC for technical support. CONCLUSIONS: Since 2007, WHO guideline development methods have become more systematic and transparent. However, some departments are bypassing the procedures, and as yet neither the GRC, nor the quality assurance

  12. Origins and early development of human body knowledge.

    Science.gov (United States)

    Slaughter, Virginia; Heron, Michelle

    2004-01-01

    As a knowable object, the human body is highly complex. Evidence from several converging lines of research, including psychological studies, neuroimaging and clinical neuropsychology, indicates that human body knowledge is widely distributed in the adult brain, and is instantiated in at least three partially independent levels of representation. Sensorimotor body knowledge is responsible for on-line control and movement of one's own body and may also contribute to the perception of others' moving bodies; visuo-spatial body knowledge specifies detailed structural descriptions of the spatial attributes of the human body; and lexical-semantic body knowledge contains language-based knowledge about the human body. In the first chapter of this Monograph, we outline the evidence for these three hypothesized levels of human body knowledge, then review relevant literature on infants' and young children's human body knowledge in terms of the three-level framework. In Chapters II and III, we report two complimentary series of studies that specifically investigate the emergence of visuo-spatial body knowledge in infancy. Our technique is to compare infants'responses to typical and scrambled human bodies, in order to evaluate when and how infants acquire knowledge about the canonical spatial layout of the human body. Data from a series of visual habituation studies indicate that infants first discriminate scrambled from typical human body picture sat 15 to 18 months of age. Data from object examination studies similarly indicate that infants are sensitive to violations of three-dimensional human body stimuli starting at 15-18 months of age. The overall pattern of data supports several conclusions about the early development of human body knowledge: (a) detailed visuo-spatial knowledge about the human body is first evident in the second year of life, (b) visuo-spatial knowledge of human faces and human bodies are at least partially independent in infancy and (c) infants' initial

  13. Collective Security Treaty Organization: Origins of the Multidimensional Mandate and Modern Means for its Implementation

    Directory of Open Access Journals (Sweden)

    Golub K.

    2018-03-01

    Full Text Available This article examines the historically contradictory development of the Collective Security Treaty Organization (CSTO following its 15th anniversary, and evaluates its political potential from the point of view of its assigned mandate. The evolution of international stability at the beginning of the century forced the contracting parties of the CSTO to formalize their mainly declarative interactions through the creation of a valid regional security organization. This new collective security forum enriched the cooperation mandate by establishing additional areas for mutual coordination including counterterrorism activities, measures to combat illegal migration and drug trafficking, strategies to respond to natural disasters and cybersecurity. The creation of the multitasking Collective Rapid Reaction Forces was the first significant step on the way to the practical realization of the CSTO. The Collective Security Strategy for the period ending in 2025 organizes the CSTO instruments of international cooperation within the CSTO crisis management framework and thus works to reduce the fragmentary nature of the CSTO. Despite the availability of the Collective Rapid Reaction Forces and the Collective Peace-Keeping Forces, the CSTO’s crisis management approach gives priority to political approaches and negotiation. Consequently, the multifunctional mandate of the CSTO predetermines its strategic role in Eurasia and allows it to achieve its political goals related to conservation of the common military and strategic area, the creation of a constraining effect, the facilitation of cooperation among law enforcement and intelligence agencies and the ability to contribute to the settlement of regional and local conflicts.

  14. Self-organized criticality and urban development

    Directory of Open Access Journals (Sweden)

    Michael Batty

    1999-01-01

    Full Text Available Urban society is undergoing as profound a spatial transformation as that associated with the emergence of the industrial city two centuries ago. To describe and measure this transition, we introduce a new theory based on the concept that large-scale, complex systems composed of many interacting elements, show a surprising degree of resilience to change, holding themselves at critical levels for long periods until conditions emerge which move the system, often abruptly, to a new threshold. This theory is called ‘self-organized criticality’; it is consistent with systems in which global patterns emerge from local action which is the hallmark of self-organization, and it is consistent with developments in system dynamics and their morphology which find expression in fractal geometry and weak chaos theory. We illustrate the theory using a unique space–time series of urban development for Buffalo, Western New York, which contains the locations of over one quarter of a million sites coded by their year of construction and dating back to 1773, some 60 years before the city began to develop. We measure the emergence and growth of the city using urban density functions from which measures of fractal dimension are used to construct growth paths of the way the city has grown to fill its region. These phase portraits suggest the existence of transitions between the frontier, the settled agricultural region, the centralized industrial city and the decentralized postindustrial city, and our analysis reveals that Buffalo has maintained itself at a critical threshold since the emergence of the automobile city some 70 years ago. Our implied speculation is: how long will this kind of urban form be maintained in the face of seemingly unstoppable technological change?

  15. Socioeconomic status, ethnicity, culture, and immigration: examining the potential mechanisms underlying Mexican-origin adolescents' organized activity participation.

    Science.gov (United States)

    Simpkins, Sandra D; Delgado, Melissa Y; Price, Chara D; Quach, Alex; Starbuck, Elizabeth

    2013-04-01

    The integrative model for child development and ecodevelopmental theory suggest that macro factors, such as socioeconomic status, ethnicity, culture, and immigration influence the settings in which adolescents engage. The goal of this investigation was to use a combination of deductive and inductive qualitative analysis to describe the mechanisms by which these macro factors might be related to Mexican-origin adolescents' participation in organized after-school activities. Qualitative data were collected through focus group interviews with 44 adolescents, 50 parents, and 18 activity leaders from 2 neighborhoods that varied in ethnic composition and average family income. Results indicated that family socioeconomic status might be related to adolescents' participation through financial resources and parents' work. Ethnicity was identified as a predictor of participation via experiences with ethnic discrimination, particularly in the neighborhood with a low percentage of Hispanic families. Cultural values and practices were related to participants' preferences for particular activities (e.g., bilingual, church-sponsored) and adolescents' participation in activities. Immigration seemed to be a factor in parents' familiarity with and beliefs about organized activities. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

  16. Developing a Plant Culture Medium Composed of Vinasse Originating from Haematococcus Pluvialis Culture

    International Nuclear Information System (INIS)

    Gollo, A. L.; Silva, A. L. L. D.; Lima, K. K. D. D.; Camara, M. C.; Rodrigues, C.; Vandenberghe, L. P. D. S.; Soccol, V. T.; Soccol, C. R.; Biasi, L. A.

    2016-01-01

    The mineral nutrients in vinasse provide support for algal and plant growth. Algal culture releases organic compounds into its liquid culture medium. These organic and inorganic substances can be useful for formulating a plant tissue culture medium, because tissue culture medium is composed of organic and inorganic components. Therefore, the aims of this study were to develop a plant culture medium by using the vinasse that is employed for Haematococcus pluvialis culture (algal filtrate); to investigate the possible beneficial effects of the biocompounds in the micropropagation of Nidularium procerum (Bromeliaceae), to evaluate quercetin content, total phenolics content in vinasse and to evaluate the cytotoxicity of the media by performing a bioassay with Artemia salina. The vinasse that originated from H. pluvialis culture can be used to formulate plant tissue culture at a 3% dilution, and its mineral nutrients can support In vitro plant growth, but some nutrients must be supplemented to enhance its efficiency. An efficient micropropagation protocol was developed for N. procerum. The micropropagated plants were suitable for transfer to the field (they were acclimatized). This culture medium provides a way to reuse wastewater, gives a rational alternative to vinasse disposal and adds value to what is currently considered to be an undesirable residue. Moreover, this process can reduce the production costs of clonal seedlings and/or bioactive compounds in biofactories. There was no apparent biostimulatory effect by the algal filtrate on morphogenesis; however, it did increase quercetin production. The H. pluvialis culture that was grown in the vinasse decreased the cytotoxicity and phenolic compound contents, which prevented explant tissue necrosis and represented a treatment for this residue for safer disposal in the environment. (author)

  17. The complete nucleotide sequence, genome organization, and origin of human adenovirus type 11

    International Nuclear Information System (INIS)

    Stone, Daniel; Furthmann, Anne; Sandig, Volker; Lieber, Andre

    2003-01-01

    The complete DNA sequence and transcription map of human adenovirus type 11 are reported here. This is the first published sequence for a subgenera B human adenovirus and demonstrates a genome organization highly similar to those of other human adenoviruses. All of the genes from the early, intermediate, and late regions are present in the expected locations of the genome for a human adenovirus. The genome size is 34,794 bp in length and has a GC content of 48.9%. Sequence alignment with genomes of groups A (Ad12), C (Ad5), D (Ad17), E (Simian adenovirus 25), and F (Ad40) revealed homologies of 64, 54, 68, 75, and 52%, respectively. Detailed genomic analysis demonstrated that Ads 11 and 35 are highly conserved in all areas except the hexon hypervariable regions and fiber. Similarly, comparison of Ad11 with subgroup E SAV25 revealed poor homology between fibers but high homology in proteins encoded by all other areas of the genome. We propose an evolutionary model in which functional viruses can be reconstituted following fiber substitution from one serotype to another. According to this model either the Ad11 genome is a derivative of Ad35, from which the fiber was substituted with Ad7, or the Ad35 genome is the product of a fiber substitution from Ad21 into the Ad11 genome. This model also provides a possible explanation for the origin of group E Ads, which are evolutionarily derived from a group C fiber substitution into a group B genome

  18. [Organization development of the public health system].

    Science.gov (United States)

    Pfaff, Holger; Klein, Jürgen

    2002-05-15

    Changes in the German health care system require changes in health care institutions. Organizational development (OD) techniques can help them to cope successfully with their changing environment. OD is defined as a collective process of learning aiming to induce intended organizational change. OD is based on social science methods and conducted by process-oriented consultants. In contrast to techniques of organizational design, OD is characterized by employee participation. One of the most important elements of OD is the so-called "survey-feedback-technique". Five examples illustrate how the survey-feedback-technique can be used to facilitate organisational learning. OD technique supports necessary change in health care organizations. It should be used more frequently.

  19. Organization of the origins of replication of the chromosomes of Mycobacterium smegmatis, Mycobacterium leprae and Mycobacterium tuberculosis and isolation of a functional origin from M. smegmatis.

    Science.gov (United States)

    Salazar, L; Fsihi, H; de Rossi, E; Riccardi, G; Rios, C; Cole, S T; Takiff, H E

    1996-04-01

    The genus Mycobacterium is composed of species with widely differing growth rates ranging from approximately three hours in Mycobacterium smegmatis to two weeks in Mycobacterium leprae. As DNA replication is coupled to cell duplication, it may be regulated by common mechanisms. The chromosomal regions surrounding the origins of DNA replication from M. smegmatis, M. tuberculosis, and M. leprae have been sequenced, and show very few differences. The gene order, rnpA-rpmH-dnaA-dnaN-recF-orf-gyrB-gyrA, is the same as in other Gram-positive organisms. Although the general organization in M. smegmatis is very similar to that of Streptomyces spp., a closely related genus, M. tuberculosis and M. leprae differ as they lack an open reading frame, between dnaN and recF, which is similar to the gnd gene of Escherichia coli. Within the three mycobacterial species, there is extensive sequence conservation in the intergenic regions flanking dnaA, but more variation from the consensus DnaA box sequence was seen than in other bacteria. By means of subcloning experiments, the putative chromosomal origin of replication of M. smegmatis, containing the dnaA-dnaN region, was shown to promote autonomous replication in M. smegmatis, unlike the corresponding regions from M. tuberculosis or M. leprae.

  20. Organic Marketing Initiatives and Rural Development

    OpenAIRE

    Schmid, Otto; Sanders, Jürn; Midmore, Peter

    2004-01-01

    Over recent decades, organic farmers have come together to form collective marketing initiatives. To begin with, such schemes were often essential as the only means of finding markets for organic products, but farmers today participate in them to pool ideas, capital and skills, and to collectively increase added value of products and market power in the supply chain. However, Organic Marketing Initiatives (OMIs) are not only initiated and managed by farmers but also by consumers, processors o...

  1. Participatory plant breeding and organic agriculture: A synergistic model for organic variety development in the United States

    Directory of Open Access Journals (Sweden)

    Adrienne C. Shelton

    2016-12-01

    Full Text Available Abstract Organic farmers require improved varieties that have been adapted to their unique soils, nutrient inputs, management practices, and pest pressures. One way to develop adapted varieties is to situate breeding programs in the environment of intended use, such as directly on organic farms, and in collaboration with organic farmers. This model is a form of participatory plant breeding, and was originally created in order to meet the needs of under-served, small-scale farmers in developing countries. A robust body of literature supports the quantitative genetic selection theory of participatory plant breeding, and helps to explain its increasing prevalence among organic breeding projects in the United States. The history of the organic farming movement in the United States highlights the cultural relevance of engaging organic farmers in the breeding process, complementing the biological rationale for participatory plant breeding. In addition, limited private investment in organic plant breeding encourages the involvement of plant breeders at public institutions. This paper synthesizes the biological, cultural, and economic justifications for utilizing participatory plant breeding as an appropriate methodology for organic cultivar development.

  2. Origin and availability of organic matter leading to arsenic mobilisation in aquifers of the Red River Delta, Vietnam

    International Nuclear Information System (INIS)

    Eiche, Elisabeth; Berg, Michael; Hönig, Sarah-Madeleine; Neumann, Thomas; Lan, Vi Mai; Pham, Thi Kim Trang; Pham, Hung Viet

    2017-01-01

    Groundwater arsenic (As) concentrations in the Red River Delta (Vietnam) are often patchy and related to the microbially induced reduction of Fe oxy-hydroxides. In this study, we explored the influence of the origin, composition and availability of natural organic matter on the hydrochemical variability in the aquifers of Van Phuc. Carbon isotope signatures (δ"1"3C_o_r_g) and C/N ratios were assessed in combination with lithology, geochemistry, hydrochemistry, hydrology and the distribution of specific biomarkers. The elationship of C/N ratios and δ"1"3C_o_r_g distinguished four groups of sediment types that differ in their organic carbon sources. This includes organic carbon originating predominantly from vascular C_3 plants (C/N: 15.4–21.0, δ"1"3C_o_r_g: −28.6 to −26.7‰), C_4 plants (C/N: 10.6; δ"1"3C_o_r_g: −14.8‰), freshwater derived particulate organic carbon (C/N: ≤8; δ"1"3C_o_r_g:≤−24‰) as well as mixtures incorporating both sources. At the high As sites, we found particulate organic carbon (POC) being 1–2‰ less depleted in δ"1"3C_o_r_g than at low As sites. More importantly, however, our assessment shows that, the availability of organic matter has to be considered decisive with regard to groundwater As contamination. Fine-grained clayey sediments overlaying sands generally protect organic matter from substantial degradation and its leaching into an adjacent aquifer. However, at the sites that are high in dissolved As in Van Phuc, sediment layers rich in organic matter are hydraulically connected to the underlying aquifer. Here, soluble organic matter seeping into the aquifer can induce and/or enhance reducing conditions, thereby mobilising As from Fe oxy-hydroxides. Our study shows that both the clay content as well as the origin of organic matter are largely controlled by the depositional environment of the sediments. - Highlights: • Particulate organic carbon (POC) from C_3/C_4 plants and freshwater is a main source of

  3. Life and Understanding: The Origins of "Understanding" in Self-Organizing Nervous Systems.

    Science.gov (United States)

    Yufik, Yan M; Friston, Karl

    2016-01-01

    This article is motivated by a formulation of biotic self-organization in Friston (2013), where the emergence of "life" in coupled material entities (e.g., macromolecules) was predicated on bounded subsets that maintain a degree of statistical independence from the rest of the network. Boundary elements in such systems constitute a Markov blanket ; separating the internal states of a system from its surrounding states. In this article, we ask whether Markov blankets operate in the nervous system and underlie the development of intelligence, enabling a progression from the ability to sense the environment to the ability to understand it. Markov blankets have been previously hypothesized to form in neuronal networks as a result of phase transitions that cause network subsets to fold into bounded assemblies, or packets (Yufik and Sheridan, 1997; Yufik, 1998a). The ensuing neuronal packets hypothesis builds on the notion of neuronal assemblies (Hebb, 1949, 1980), treating such assemblies as flexible but stable biophysical structures capable of withstanding entropic erosion. In other words, structures that maintain their integrity under changing conditions. In this treatment, neuronal packets give rise to perception of "objects"; i.e., quasi-stable (stimulus bound) feature groupings that are conserved over multiple presentations (e.g., the experience of perceiving "apple" can be interrupted and resumed many times). Monitoring the variations in such groups enables the apprehension of behavior; i.e., attributing to objects the ability to undergo changes without loss of self-identity. Ultimately, "understanding" involves self-directed composition and manipulation of the ensuing "mental models" that are constituted by neuronal packets, whose dynamics capture relationships among objects: that is, dependencies in the behavior of objects under varying conditions. For example, movement is known to involve rotation of population vectors in the motor cortex (Georgopoulos et al

  4. NEW TRENDS IN ORGANIZATION INFORMATION SYSTEMS DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Codruţ MITROI

    2014-10-01

    Full Text Available An organization’s architecture is the rigorous description of its structure that includes organization components (entities, their features, as well as the relationships among them. This description must be comprehensive and include organization goals, mechanisms, and rules, internal and external processes, as well as technology. The architecture must be structured by layers and the interaction among these contributes to achieving organization goals. In this respect, specialized literature provides several approaches depending on the perspective taken on an organization: the management/owner perspective, organization process designer view or process administrator view. One of these is actually the mix of business process view and information view, with the following components for the latter in most cases: data architecture, application architecture, technological resources architecture.

  5. Origin of particulate organic carbon in the marine atmosphere as indicated by it stable carbon isotopic composition

    International Nuclear Information System (INIS)

    Chesselet, R.; Fontugne, M.; Buat-Menard, P.; Ezat, U.; Lambert, C.E.

    1981-01-01

    Organic carbon concentration and isotopic composition were determined in samples of atmospheric particulate matter collected in 1979 at remote marine locations (Enewetak atoll, Sargasso Sea) during the SEAREX (Sea-Air Exchange) program field experiments. Atmospheric Particulate Organic Carbon (POC) concentrations were found to be in the range of 0.3 to 1.2 mg. m -3 , in agreement with previous literature data. The major mass of POC was found on the smallest particles (r 13 C/ 12 C of the small particles is close to the one expected (d 13 C = 26 +- 2 0 //sub infinity/) for atmospheric POC of continental origin. For all the samples analysed so far, it appears that more than 80% of atmospheric POC over remote marine areas is of continental origin. This can be explained either by long-range transport of small sized continental organic aserosols or by the production of POC in the marine atmosphere from a vapor phase organic carbon pool of continental origin. The POC in the large size fraction of marine aerosols ( 13 C = -21 +- 2 0 / 00 ) for POC associated with sea-salt droplets transported to the marine atmosphere

  6. Review Of Development And Characteristics Of Organic Agriculture In Croatia

    Directory of Open Access Journals (Sweden)

    Kristina Petljak

    2011-12-01

    Full Text Available In the last decade, an ever increasing interest of both foreign and domestic academic and general public for organic agriculture can be observed. Organic agriculture, as a new agricultural production system, enables full utilization of farming potentials while satisfying social and economic needs and preserving natural ecosystem and environment. Act on Organic Production of Agricultural Products and Foodstuffs provides an elementary strategic frame for agricultural production development in Republic of Croatia. This article gives an overview of organic agriculture legislation in Croatia and detailed analysis of development periods of organic agriculture. Special emphasis is put on structure of organic production which highlights data on organic plant and animal production in Croatia. The paper provides a comparison between levels of organic agriculture development in the world (with the special emphasis on Europe and in Croatia, as well as the overview of main obstacles towards more significant development of organic agriculture in Republic of Croatia.

  7. Developments in breeding cereals for organic agriculture

    DEFF Research Database (Denmark)

    Wolfe, M.S.; Baresel, J.P.; Desclaux, D.

    2008-01-01

    into the crop can be helped by diversification within the crop, allowing complementation and compensation among plants. Although the problems of breeding cereals for organic farming systems are large, there is encouraging progress. This lies in applications of ecology to organic crop production, innovations......The need for increased sustainability of performance in cereal varieties, particularly in organic agriculture (OA), is limited by the lack of varieties adapted to organic conditions. Here, the needs for breeding are reviewed in the context of three major marketing types, global, regional, local......, in European OA. Currently, the effort is determined, partly, by the outcomes from trials that compare varieties under OA and CA (conventional agriculture) conditions. The differences are sufficiently large and important to warrant an increase in appropriate breeding. The wide range of environments within OA...

  8. Origin and fate of organic matter in sandy soils along a primary vegetation succession

    NARCIS (Netherlands)

    Nierop, K.

    1999-01-01

    Until now little is known about the role vegetation plays in the organic matter formation, particularly at the molecular level. Most ecosystems have a long history, which is unknown or too complex to find distinct relations between vegetation and the chemical composition of soil organic

  9. GLOBAL CONSULTATION ON ESTABLISHMENT A UNIFIED SURVEILLANCE SYSTEM FOR DONATION AND TRANSPLANTATION OF ORGANS, TISSUES AND CELLS OF HUMAN ORIGIN

    Directory of Open Access Journals (Sweden)

    O. V. Orlova

    2011-01-01

    Full Text Available From from February 7th to 9th 2011, the World Health Organization (WHO, the Italian National Transplant Cen- tre and the EU-funded Project «Vigilance and Surveillance of Substances of Human Origin» joined forces to organise a major global consultation that took place in Bologna, Italy. The scope of the project included organs, tissues and cells for transplantation and for assisted reproduction. The participants represented regulatory and non-regulatory government agencies, professional societies and scientific and clinical specialities from all WHO regions. The meeting explored the work already carried out on-line and agreed on priorities for the future deve- lopment of the Project «Vigilance and Surveillance of Substances of Human Origin». 

  10. Calorimetric analysis points out the physical-chemistry of organic olive oils and reveals the geographical origin

    Science.gov (United States)

    Mallamace, Domenico; Vasi, Sebastiano; Corsaro, Carmelo; Naccari, Clara; Clodoveo, Maria Lisa; Dugo, Giacomo; Cicero, Nicola

    2017-11-01

    The thermal properties of many organic extra Virgin Olive Oils (eVOOs) coming from different countries of the world were investigated by Differential Scanning Calorimetry (DSC). This technique, through a series of heating and cooling cycles, provides a specific curve, i.e., a thermogram, which represents the fingerprint of each eVOO sample. In fact, variations due to the different cultivars, geographical origin or chemical composition can be highlighted because they produce changes in the corresponding thermogram. In particular, in this work, we show the results of an unsupervised multivariate statistical analysis applied to the DSC thermograms of many organic eVOOs. This analysis allows us to discriminate the geographical origin of the different studied samples in terms of the peculiar features shown by the melting profiles of the triacylglycerol moieties.

  11. Search for EPR markers of the history and origin of the insoluble organic matter in extraterrestrial and terrestrial rocks

    Science.gov (United States)

    Gourier, Didier; Binet, Laurent; Scrzypczak, Audrey; Derenne, Sylvie; Robert, François

    2004-05-01

    The insoluble organic matter (IOM) of three carbonaceous meteorites (Orgueil, Murchison and Tagish Lake meteorites) and three samples of cherts (microcrystalline SiO 2 rock) containing microfossils with age ranging between 45 million years and 3.5 billion years is studied by electron paramagnetic resonance (EPR). The age of the meteorites is that of the solar system (4.6 billion years). The purpose of this work was to determine the EPR parameters, which allow us to discriminate between biogenic and extra terrestrial origin for the organic matter. Such indicators should be relevant for the controversy regarding the biogenicity of the organic matter in the oldest cheroot (3.5 billion years) and in Martian meteorites containing microbe-like microstructures. The organic matter of meteorites contains a high concentration of diradicaloid moieties characterised by a diamagnetic ground state S=0 and a thermally accessible triplet state S=1. The three meteorites exhibit the same singlet-triplet gap (ST gap) Δ E≈0.1 eV. To the best of our knowledge, such diradicaloids are unknown in insoluble organic matter of terrestrial origin. We have also shown that the EPR linewidth of insoluble organic matter in cherts and coals decrease logarithmically with the age of the organic matter. We conclude from this result that the organic matter in the oldest cherts (3.5 billion years) has the same age as their SiO 2 matrix, and is not due to a latter contamination by bacteria, as was recently found in meteoritic samples.

  12. Original Thinking

    Directory of Open Access Journals (Sweden)

    Ashok Natarajan

    2012-04-01

    Full Text Available History that comes to us as a chronology of events is really a collective existence that is evolving through several stages to develop Individuality in all members of the society. The human community, nation states, linguistic groups, local castes and classes, and families are the intermediate stages in development of the Individual. The social process moves through phases of survival, growth, development and evolution. In the process it organizes the consciousness of its members at successive levels from social external manners, formed behavior, value-based character and personality to culminate in the development of Individuality. Through this process, society evolves from physicality to Mentality. The power of accomplishment in society and its members develops progressively through stages of skill, capacity, talent, and ability. Original thinking is made possible by the prior development of thinking that organizes facts into information. The immediate result of the last world war was a shift in reliance from physical force and action to mental conception and mental activity on a global scale. At such times no problem need defy solution, if only humanity recognizes the occasion for thinking and Original Thinking. The apparently insoluble problems we confront are an opportunity to formulate a comprehensive theory of social evolution. The immediate possibility is to devise complete solutions to all existing problems, if only we use the right method of thought development.

  13. Irreversibility and self-organization in spin glasses. 1. Origin of irreversibility in spin glasses

    International Nuclear Information System (INIS)

    Kovrov, V.P.; Kurbatov, A.M.

    1989-05-01

    The origin of irreversibility in spin glasses is found out on the basis of the analytical study of the well-known TAP equations. Connection between irreversible jumpwise transitions and a positive feedback in spin glasses is discussed. (author). 7 refs, 4 figs

  14. Origin of colour stability in blue/orange/blue stacked phosphorescent white organic light-emitting diodes

    International Nuclear Information System (INIS)

    Kim, Sung Hyun; Jang, Jyongsik; Yook, Kyoung Soo; Lee, Jun Yeob

    2009-01-01

    The origin of colour stability in phosphorescent white organic light-emitting diodes (PHWOLEDs) with a blue/orange/blue stacked emitting structure was studied by monitoring the change in a recombination zone. A balanced recombination zone shift between the blue and the orange light-emitting layers was found to be responsible for the colour stability in the blue/orange/blue stacked PHWOLEDs.

  15. COMPARATIVE STUDY OF ORGANIC MENTAL DISORDERS OF VASCULAR ORIGIN WITH PARTICIPANTS OF THE LIQUIDATION OF THE CHERNOBYL ACCIDENT

    Directory of Open Access Journals (Sweden)

    G. M. Rumyantseva

    2011-01-01

    Full Text Available The result of the carried investigation of participants of liquidation of Chernobyl accident consequences, suffering from organic disease of a brain of a vascular origin with mental infringements, and patients with the similar pathology, not exposed with radiating influence, revealed a number of the сlinico- psychopathological and paraclinical peculiarities testifying heavier current of disease among liquidators, forming a chronic ischemic condition of a brain, and the atrophy phenomena among mentioned group.

  16. COMPARATIVE STUDY OF ORGANIC MENTAL DISORDERS OF VASCULAR ORIGIN WITH PARTICIPANTS OF THE LIQUIDATION OF THE CHERNOBYL ACCIDENT

    OpenAIRE

    G. M. Rumyantseva; T. M. Levina; O. V. Chinkina

    2011-01-01

    The result of the carried investigation of participants of liquidation of Chernobyl accident consequences, suffering from organic disease of a brain of a vascular origin with mental infringements, and patients with the similar pathology, not exposed with radiating influence, revealed a number of the сlinico- psychopathological and paraclinical peculiarities testifying heavier current of disease among liquidators, forming a chronic ischemic condition of a brain, and the atrophy phenomena among...

  17. PHYS: Division of Physical Chemistry 258 - Properties and Origins of Cometary and Asteroidal Organic Matter Delivered to the Early Earth

    Science.gov (United States)

    Messenger, Scott; Nguyen, Ann

    2017-01-01

    extraterrestrial materials and returned samples are essential to understand the origins of Solar System organic material and the roles of comets and asteroids to providing the starting materials for the emergence of life.

  18. On the origin of organic molecules in interstellar space and some of its consequences

    International Nuclear Information System (INIS)

    Johansson, K.L.V.

    1981-01-01

    The possible sources of complex organic molecules observed in the interstellar space are discussed. It is found that a leakage from lifebearing planets cannot possibly explain the observed amounts of complex organic molecules. They are probably formed in interstellar clouds, either free in space or on the surface of grains. This opens the possibility that planets (also the earth) moving through such clouds may have collected appreciable amounts of complex organic molecules. It would therefore be feasible to perform experiments like the Urey-Miller's, starting with a considerably more complex mixture than the traditional one. (Auth.)

  19. The development of organized visual search

    Science.gov (United States)

    Woods, Adam J.; Goksun, Tilbe; Chatterjee, Anjan; Zelonis, Sarah; Mehta, Anika; Smith, Sabrina E.

    2013-01-01

    Visual search plays an important role in guiding behavior. Children have more difficulty performing conjunction search tasks than adults. The present research evaluates whether developmental differences in children's ability to organize serial visual search (i.e., search organization skills) contribute to performance limitations in a typical conjunction search task. We evaluated 134 children between the ages of 2 and 17 on separate tasks measuring search for targets defined by a conjunction of features or by distinct features. Our results demonstrated that children organize their visual search better as they get older. As children's skills at organizing visual search improve they become more accurate at locating targets with conjunction of features amongst distractors, but not for targets with distinct features. Developmental limitations in children's abilities to organize their visual search of the environment are an important component of poor conjunction search in young children. In addition, our findings provide preliminary evidence that, like other visuospatial tasks, exposure to reading may influence children's spatial orientation to the visual environment when performing a visual search. PMID:23584560

  20. Origin of heat-induced structural changes in dissolved organic matter

    Czech Academy of Sciences Publication Activity Database

    Drastík, M.; Novák, František; Kučerík, J.

    2013-01-01

    Roč. 90, č. 2 (2013), s. 789-795 ISSN 0045-6535 Institutional support: RVO:60077344 Keywords : dissolved organic matter * humic substances * hydration * hysteresis Subject RIV: DF - Soil Science Impact factor: 3.499, year: 2013

  1. A kinetic study of the formation of organic solids from formaldehyde: Implications for the origin of extraterrestrial organic solids in primitive Solar System objects

    Science.gov (United States)

    Kebukawa, Yoko; Cody, George D.

    2015-03-01

    Aqueous organic solid formation from formaldehyde via the formose reaction and subsequent reactions is a possible candidate for the origin of complex primitive chondritic insoluble organic matter (IOM) and refractory carbon in comets. The rate of formation of organic solids from formaldehyde was studied as a function of temperature and time, with and without ammonia, in order to derive kinetic expressions for polymer yield. The evolution in molecular structure as a function of time and temperature was studied using infrared spectroscopy. Using these kinetic expressions, the yield of organic solids is estimated for extended time and temperature ranges. For example, the half-life for organic solid formation is ∼5 days at 373 K, ∼200 days at 323 K, and ∼70 years at 273 K with ammonia, and ∼25 days at 373 K, ∼13 years at 323 K, and ∼2 × 104 years at 273 K without ammonia. These results indicate that organic solids could form during the aqueous alteration in meteorite parent bodies. If liquid water existed early in the interiors of Kuiper belt objects (KBOs), formaldehyde could convert into organic solids at temperatures close to 273 K, and possibly even below 273 K in the ammonia-water system.

  2. WIN Bulgaria - organization with history and development

    International Nuclear Information System (INIS)

    Tsokova, L.

    2011-01-01

    The report presents information about the establishing, activities and perspectives of WIN Global and WIN Bulgaria - the history of the association, structure, organization, goals and tasks. The social involvement is expressed by issuing of declarations, opinions, memoranda and other documents on important problems in the nuclear area, connected with the power plan, waste management facilities etc

  3. Entropy and Self-Organization - An Open System Approach to the Origins of Homeland Security Threats

    Science.gov (United States)

    2015-06-01

    to properly understand homeland security threats and their origin directly impacts our ability to prevent or mitigate these threats. “Homeland...of new cognitive approaches or policy tools to eliminate or mitigate homeland security threats, perhaps even at the level of their root causes. A key...to self-similar ‘fractal’ structure. The frequency spectrum of 1/f noise or flicker noise with a power-law spectrum S (f) ≈ f⁻β.” Bak, Tang, and

  4. Market development of organic products in Europe: conditions and role of Organic Marketing Initiatives

    OpenAIRE

    Schmit, Otto; Fontguyon, Guy de; Sans, Pierre

    2007-01-01

    The contribution presents some of the main results of a European program of investigation (titled Organic Marketing Initiatives – OMIs – and Rural Development). Firstly, consumer behavior, as well as attitudes, expectations, motives and buying barriers concerning organic food are explored. Then, authors give a brief overview of the organic market analysis of 18 European countries, based on a Delphi inquiry. Finally, the third part highlights the role of OMIs in the organic market development ...

  5. Origin and evolution of the self-organizing cytoskeleton in the network of eukaryotic organelles.

    Science.gov (United States)

    Jékely, Gáspár

    2014-09-02

    The eukaryotic cytoskeleton evolved from prokaryotic cytomotive filaments. Prokaryotic filament systems show bewildering structural and dynamic complexity and, in many aspects, prefigure the self-organizing properties of the eukaryotic cytoskeleton. Here, the dynamic properties of the prokaryotic and eukaryotic cytoskeleton are compared, and how these relate to function and evolution of organellar networks is discussed. The evolution of new aspects of filament dynamics in eukaryotes, including severing and branching, and the advent of molecular motors converted the eukaryotic cytoskeleton into a self-organizing "active gel," the dynamics of which can only be described with computational models. Advances in modeling and comparative genomics hold promise of a better understanding of the evolution of the self-organizing cytoskeleton in early eukaryotes, and its role in the evolution of novel eukaryotic functions, such as amoeboid motility, mitosis, and ciliary swimming. Copyright © 2014 Cold Spring Harbor Laboratory Press; all rights reserved.

  6. Self-organized complex space charge configurations at the origin of flicker noise

    International Nuclear Information System (INIS)

    Popescu, S.; Lozneanu, E.; Sanduloviciu, M.

    2003-01-01

    Based on experimental results obtained from a plasma diode we explain the fluctuations of the voltage supported by a non-linear gaseous conductor by the dynamical behavior of spatiotemporal patterns, in the form of moving double layers, formed after self-organization. Such phenomena appear when the system is subjected to an external constraint that creates and maintains a local gradient of electron kinetic energy. The described phenomenology suggests a plausible explanation for the appearance of flicker noise also in other physical systems, as for example semiconductors and, implicitly, offers a new model for the so-called self-organized criticality concept

  7. Researches on Agricultural Cooperative Economic Organization Promoting Agricultural Insurance Development

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The advantages of cooperative economic organization being the effective carrier of agricultural insurance development are analyzed. Firstly, cooperative economic organization promotes scale management and solves the problem of decentralized operation of small households. Secondly, cooperative economic organization can settle the problem of peasants’ low systematization. Thirdly, cooperative economic organization can largely reduce the costs of agricultural insurance operation. Fourthly, cooperative organization decreases moral risks as well as adverse selection to some extent. Lastly, cooperative organization, to a certain degree, reduces the risks of agricultural production and increases the insurability of agricultural risks. Meanwhile, limitations of agricultural cooperative economic organization being the carrier of agricultural insurance operation are pointed out. Firstly, cooperative economic organization has limited coverage and small size of organization, which is harmful to the diversification of agricultural risks. Secondly, cooperative economic organization lacks capital funds and its development is not standard, which is not perfect for the function exertion as a carrier. Lastly, members of professional cooperative organization have low cultural qualities, which restrict the implementation of agricultural insurance. The modes of farmers’ cooperative economic organization promoting agricultural insurance development are proposed, including mode of agricultural insurance cooperative ( mutual corporation), mode of "leading enterprises (companies) + professional cooperative organization (planting majors) + insurance" and mode of professional cooperatives serving as agricultural insurance agent. Last of all, the promoting role of agricultural insurance in agricultural cooperative economic organization is briefly illustrated.

  8. Recent developments in persufflation for organ preservation.

    Science.gov (United States)

    Min, Catherine G; Papas, Klearchos K

    2018-06-01

    To summarize current literature and recent findings on the potential of humidified oxygenated gas perfusion (persufflation) as an alternative method for improved organ preservation. Although there are some conflicting data, the majority of the evidence suggests that persufflation, by enhancing oxygenation, can improve preservation and even rescue organs, including organs with prior exposure to warm ischemia. In some cases, persufflation produced better results than hypothermic machine perfusion. The timing of persufflation is of importance; benefits of persufflation appear to increase as the timing of its administration postprocurement decreases. This may be particularly true for tissues that are more sensitive to ischemia, such as the pancreas prior to islet isolation. Combining oxygen persufflation with nitric oxide and addition of pulsatile flow may provide further benefits and amplify its effects on improving transplant outcomes. Persufflation is a promising, relatively simple, preservation technique that enables improved oxygenation, which provides protection and improvement in the graft condition during preservation and prior to transplantation. More detailed studies are needed to optimize persufflation and evaluate its short and long-term effects in vivo.

  9. Leadership for democracy : developing democratic organizations

    OpenAIRE

    Dorczak, Roman

    2014-01-01

    What seems to be one of the core values that shapes our understanding of the main goals of educational institutions is development. It should be discussed on at least four different levels: individual, group, organizational and social. Individual human development should be seen as the most important precondition for all the other types or levels of development. Using L. Kohlberg’s theory of socio-moral development, the paper discusses necessary organizational changes in schools necessary to ...

  10. Effect of origin and composition of diet on ecological impact of the organic egg production chain

    NARCIS (Netherlands)

    Dekker, S.E.M.; Boer, de I.J.M.; Krimpen, van M.M.; Aarnink, A.J.A.; Groot Koerkamp, P.W.G.

    2013-01-01

    The objective of this research was to assess the potential to reduce the integral ecological impact (i.e. impact along the egg production chain per kg egg) of Dutch organic egg production by replacing currently used imported diet ingredients with Dutch diet ingredients. We realized this objective by

  11. Tracing the origin of dissolved organic matter (DOM) in subterranean estuaries using colored DOM and amino acids

    Science.gov (United States)

    Kim, T.; Kwon, E.; Kim, G.

    2011-12-01

    In order to determine the origin of dissolved organic matter (DOM) in the subterranean estuary (STE), the mixing zone of fresh terrestrial groundwater and recirculating seawater in a coastal permeable aquifer, we conducted water sampling from two STEs with different geological settings: (1) Jeju Island beaches (Hwasun and Samyang), which are composed of volcanic rocks and sandy sediments, and (2) Hampyeong beach, which is located in a large intertidal, sandy flat zone. The distributions of salinity, total hydrolysable amino acids (THAA), dissolved organic carbon (DOC), and colored DOM (CDOM) were measured for groundwater samples in these STEs. In the Hwasun STE, the humic-like peak decreases with increasing salinity, whereas the protein-like peak does not show a clear relationship with salinity. In contrast, in the Samyang STE, both humic-like peak and protein-like peak increase with increasing salinity. These contrasting results indicate that DOM in the Hwasun STE originates mainly from terrestrial inputs, while that in the Samyang STE originates mainly from biological and/or microbial activities. In the Hampyeong STE, we observed good correlations among the biodegradation index, alanine D/L ratios, THAA concentrations, DOC, and CDOM index (both humic-like and protein-like). Together with their geographical distribution patterns, these correlations indicate that DOM in the Hampyeong STE is mainly derived from marine sediments in the course of seawater recirculation. Our study shows that CDOM and amino acids are excellent tracers of DOM in the STE where DOM is derived from diverse sources.

  12. Test the Artifact - Develop the Organization

    DEFF Research Database (Denmark)

    Bossen, Claus

    2006-01-01

    perspective is applied to data acquired by the qualitative methodsof participant observation and semi-structured open-ended interviews. Conclusions: The achievement of fit between IT technology and work processes in healthcare involves the establishment of new organizational structures that cut across...... the existingdivisionalized hospital organization and a detailed alignment of artefact, functionalityand work process. This process can be furthered by supporting ‘communities of practice',i.e. informal groups of engaged clinicians. A sociotechnical perspective is beneficial to theanalysis of such processes....

  13. Chemical and isotopic composition of marine organic matter as indicators of its origin

    International Nuclear Information System (INIS)

    Malej, A.

    1989-07-01

    The present study was carried out to evaluate the relative importance of marine and terrestrial sources of Particulate Organic Matter (POM) in the Northern Adriatic Sea. Samples of POM were obtained from the water column at 14 stations using Niskin bottles at 4 depths and sediment traps (placed near the sea floor). Additional samples were obtained of likely source organic matter: sewage, river POM, phytoplankton bloom material, zooplankton, jelly-fish and bethic macrophytes. All samples were analyzed for total carbon and nitrogen and the delta C-13/C-12 ratio (by mass spectrometry). Marine and terrestrial sources of POM were clearly distinguished by their isotopic ratios. A linear model was set up to evaluate the relative importance of these sources at each sampling station. Except in the immediate vicinity of river sources, the marine component appears to dominate. 7 refs, 5 figs, 1 tab

  14. Isotopic compositions and probable origins of organic molecules in the Eocene Messel shale

    Science.gov (United States)

    Hayes, J. M.; Takigiku, Ray; Ocampo, Ruben; Callot, Enry J.; Albrecht, Pierre

    1987-01-01

    It is shown here that the carbon isotopic compositions of biomarkers from the Eocene Messel shale, accumulated 47 + or - 2 million years ago in anaerobic waters at the bottom of a lake, allow identification of specific sources for some materials and reconstruction of carbon flows within the lake and its sediments. The C-13 content of organic matter synthesized by lacustrine primary producers can be estimated from the observed C-13 content of the geoporphyrins derived from their chlorophylls. Total organic material in the shale is depleted in C-13 by six parts per thousand relative to that input. This difference cannot be explained by selective loss of components enriched in C-13, nor, as shown by isotopic compositions of other biomarkers, by inputs from land plants surrounding the lake or from methanogenic bacteria.

  15. Original article The regulative function of mentalization and mindfulness in borderline personality organization

    OpenAIRE

    Monika Marszał; Dominika Górska

    2015-01-01

    Background The aim of this study was to broaden the understanding of the emotional difficulties of borderline personality organization (BPO) by reference to a meta-ability named ‘orientation on the internal world’, here conceptualized as mentalization and mindfulness, in the framework of object relation theory. It was assumed that it is not mentalization “in itself”, but mainly its regulatory function, that is important for BPO. Participants and procedure The clinical and ...

  16. Presynaptic proteoglycans: sweet organizers of synapse development.

    Science.gov (United States)

    Song, Yoo Sung; Kim, Eunjoon

    2013-08-21

    Synaptic adhesion molecules control neuronal synapse development. In this issue of Neuron, Siddiqui et al. (2013) and de Wit et al. (2013) demonstrate that LRRTM4, a postsynaptic adhesion molecule, trans-synaptically interacts with presynaptic heparan sulfate proteoglycans (HSPGs) to promote synapse development. Copyright © 2013 Elsevier Inc. All rights reserved.

  17. The Organization for Economic Cooperation and Development

    Science.gov (United States)

    2013-10-30

    India , Indonesia, and South Africa with a view toward possible membership. The member countries rely on the OECD Secretariat in Paris to collect...science and technology, internet, tax and anti-bribery standards, gender , green growth; public management; and globalization and development. One... inequality that arises from necessary economic adjustments. In addition, the initiative will address the needs and issues of developing countries

  18. Importance of Career Development for Individuals and Organizations

    Directory of Open Access Journals (Sweden)

    Mustafa Serbes

    2017-11-01

    Full Text Available Career development and planning is very significant to carry the organizations from current to the higher levels as well as professional and personal developments of the individuals. In terms of career, it can be said that the individuals and the organizations who invest in the career development can keep up with the others in the market. This paper tries to shed a light upon the importance of career development and shows basic traits of the career development.

  19. Development of new organic materials by radiation

    Energy Technology Data Exchange (ETDEWEB)

    Nho, Y. C.; Kang, P. H.; Choi, J. H.; and others

    2012-01-15

    The aims of this project is to develop the high-performance industrial and biomedical new materials and finally contribute to the advancement of the national radiation technology industry. In the 1st project, we have developed the radiation-based new therapeutic agents such as hydrogel patch, paste, naganol, nanoparticles and nano fibers containing natural medicinal materials for the treatment of atomic dermatitis and diabetic ulcer. Also, we have developed the separator, the polymer gel electrolyte, and proton exchange membranes for lithium secondary battery and fuel cell by radiation. In the 2nd project, we have developed the advanced composite materials such as silicon carbide fibers, carbon fiber reinforced plastics, low dielectric materials for semiconductor and adhesive technology. In the 3rd project, the crucial radiation-induced surface modification technologies for the fabrication of the advanced biosensors/chips and electronic devices have been successfully developed.

  20. Development of new organic materials by radiation

    International Nuclear Information System (INIS)

    Nho, Y. C.; Kang, P. H.; Choi, J. H.

    2012-01-01

    The aims of this project is to develop the high-performance industrial and biomedical new materials and finally contribute to the advancement of the national radiation technology industry. In the 1st project, we have developed the radiation-based new therapeutic agents such as hydrogel patch, paste, naganol, nanoparticles and nano fibers containing natural medicinal materials for the treatment of atomic dermatitis and diabetic ulcer. Also, we have developed the separator, the polymer gel electrolyte, and proton exchange membranes for lithium secondary battery and fuel cell by radiation. In the 2nd project, we have developed the advanced composite materials such as silicon carbide fibers, carbon fiber reinforced plastics, low dielectric materials for semiconductor and adhesive technology. In the 3rd project, the crucial radiation-induced surface modification technologies for the fabrication of the advanced biosensors/chips and electronic devices have been successfully developed

  1. Law and Islamic finance: How legal origins affect Islamic finance development?

    Directory of Open Access Journals (Sweden)

    Rihab Grassa

    2014-09-01

    Full Text Available Many researchers have shown that differences in legal origin explain differences in financial development. Using historical comparisons and cross-country regressions for 30 countries observed for the period from 2005 to 2010, this study tried to assess if different legal origins impacted on the development of Islamic finance. More particularly, this paper tried to assess empirically why and how Shari'a Law's legal origins adopted wholly or partially (combined with Common or Civil Law could explain the level of development of Islamic finance in different jurisdictions. Firstly, we found that countries adopting a Shari'a legal system had a very well developed Islamic financial system. Secondly, we found that countries, adopting a mixed legal system based on Common Law and Shari'a Law, were characterized by the flexibility of their legal systems to make changes to their laws in response to the changing socioeconomic conditions and that these helped the development of the Islamic financial industry. However, we found that countries, adopting a mixed legal system based on both Civil Law and Shari'a Law, were less flexible in making changes to their old laws and this thwarted the development of the Islamic financial industry in these countries. Thirdly, we found that the concentration of Muslim population (the percentage of Muslim population had a positive effect on the development of the Islamic banking system. Also, the level of income had a positive and significant effect on the development of Islamic banking.

  2. Self-organized patterns along sidewalls of iron silicide nanowires on Si(110) and their origin

    Energy Technology Data Exchange (ETDEWEB)

    Das, Debolina; Mahato, J. C.; Bisi, Bhaskar; Dev, B. N., E-mail: msbnd@iacs.res.in [Department of Materials Science, Indian Association for the Cultivation of Science, Kolkata 700032 (India); Satpati, B. [Surface Physics and Material Science Division, Saha Institute of Nuclear Physics, 1/AF Bidhannagar, Kolkata 700064 (India)

    2014-11-10

    Iron silicide (cubic FeSi{sub 2}) nanowires have been grown on Si(110) by reactive deposition epitaxy and investigated by scanning tunneling microscopy and scanning/transmission electron microscopy. On an otherwise uniform nanowire, a semi-periodic pattern along the edges of FeSi{sub 2} nanowires has been discovered. The origin of such growth patterns has been traced to initial growth of silicide nanodots with a pyramidal Si base at the chevron-like atomic arrangement of a clean reconstructed Si(110) surface. The pyramidal base evolves into a comb-like structure along the edges of the nanowires. This causes the semi-periodic structure of the iron silicide nanowires along their edges.

  3. The Influences of the Family of Origin on Career Development: A Review and Analysis. Major Contribution

    Science.gov (United States)

    Whiston, Susan C.; Keller, Briana K.

    2004-01-01

    Based on a developmental contextual perspective advocated by Vondracek, Lerner, and Schulenberg, this article provides a comprehensive review of the research published since 1980 related to family of origin influences on career development and occupational choice. Because individuals are most likely to seek assistance with career decisions from…

  4. Development of new organic materials by radiation

    International Nuclear Information System (INIS)

    Nho, Young Chang; Kang, Phil Hyun; Choi, Jae Hak

    2010-04-01

    The aims of this project is to develop the high-performance industrial and biomedical new materials and finally contribute to the advancement of the national radiation technology industry. In the 1st project, we carried out the radiation-based new research to apply long-term moisturizing effects and effective natural herbal extracts on the atopic wounds using gamma-ray irradiation. Also, we have developed the separator and the polymer gel electrolyte for lithium secondary battery by radiation. In the 2nd project, we have developed the advanced composite materials such as silicon carbide fibers, carbon fiber reinforced plastics, low dielectric materials for semiconductor and adhesive technology for TFT-LCD panel by radiation. In the 3rd project, we have developed the various radiation-based techniques for the surface modification of polymers and ceramics, biomolecules immobilization and patterning, prevention of biomolecule's non-specific adhesion, and surface modification of carbon nanotubes

  5. Development of emotions as organized by culture

    OpenAIRE

    Trommsdorff, Gisela

    2006-01-01

    Emotions can be seen as both biologically prepared and socio-culturally shaped. Evidence on cultural differences in manifestations of emotion abound; however, the role of culture in emotion development has not yet been systematically studied and integrated in a theory on the socialization of emotions. Emotion development includes the understanding of emotions and their meaning, appraisal of emotion-evoking situations, knowledge of appropriate emotion expression, and regulation of emotions. Em...

  6. Reconstructing Religion : An Anthropological Study on the Development of Dejiao Organization in Contemporary Malaysia

    OpenAIRE

    HUANG, Yun

    2012-01-01

    This paper examines the development and the formation of the Dejiao organization. Dejiao originated as a spirit-writing cult in 1939 in the Teochew region of South China. Dejiao is largely a Teochew phenomenon with a close link to Teochew religious culture and Teochew businessmen. By the end of World War II, Teochew businessmen had begun spreading Dejiao to areas of Southeast Asia, such as Thailand, Singapore and Malaysia. Since then, it has continued to expand, and today Dejiao has developed...

  7. Tunneling and Origin of Large Access Resistance in Layered-Crystal Organic Transistors

    Science.gov (United States)

    Hamai, Takamasa; Arai, Shunto; Minemawari, Hiromi; Inoue, Satoru; Kumai, Reiji; Hasegawa, Tatsuo

    2017-11-01

    Layered crystallinity of organic semiconductors is crucial to obtaining high-performance organic thin-film transistors (OTFTs), as it allows both smooth-channel-gate-insulator interface formation and efficient two-dimensional carrier transport along the interface. However, the role of vertical transport across the crystalline molecular layers in device operations has not been a crucial subject so far. Here, we show that the interlayer carrier transport causes unusual nonlinear current-voltage characteristics and enormous access resistance in extremely high-quality single-crystal OTFTs based on 2-decyl-7-phenyl[1]-benzothieno[3 ,2 -b ][1]benzothiophene (Ph -BTBT -C10 ) that involve inherent multiple semiconducting π -conjugated layers interposed, respectively, by electrically inert alkyl-chain layers. The output characteristics present layer-number (n )-dependent nonlinearity that becomes more evident at larger n (1 ≤n ≤15 ), demonstrating tunneling across multiple alkyl-chain layers. The n -dependent device mobility and four-probe measurements reveal that the alkyl-chain layers generate a large access resistance that suppresses the device mobility from the intrinsic value of about 20 cm2 V-1 s-1 . Our findings clarify the reason why device characteristics are distributed in single-crystal OTFTs.

  8. Enrichment of deuterium in insoluble organic matter from primitive meteorites: A solar system origin?

    Science.gov (United States)

    Remusat, Laurent; Palhol, Fabien; Robert, François; Derenne, Sylvie; France-Lanord, Christian

    2006-03-01

    Because of a systematic enrichment in deuterium, the insoluble organic matter (IOM) of the carbonaceous chondrites is considered to have formed in the interstellar medium. However, the D / H ratios in IOM remain much lower than those measured in the organic molecules commonly observed in the dense interstellar medium. In this study, the D / H ratio of different aromatic and aliphatic molecular fragments of IOM from the Orgueil meteorite was measured by GC-irMS (gas chromatography-isotopic ratio mass spectrometry). No correlation was observed between the D / H ratios and structural parameters characterizing the IOM, such as the H / C ratio. However, the δD of the benzylic, aliphatic and aromatic hydrogen into the IOM can be determined to be 1250‰, + 550‰ and + 150‰, respectively, relative to SMOW. This indicates that D-enrichment in IOM is correlated with the C-H bond dissociation energy. Such a correlation rules out IOM formation from observed interstellar molecules and suggests instead that the different components of IOM have acquired their D / H ratios by an exchange with a deuterium-rich reservoir after its synthesis. The same process can be invoked to account for the D / H composition of meteoritic water. Findings point to a common process for deuterium enrichment in the solar system.

  9. Organized labor and the origins of the Occupational Safety and Health Act.

    Science.gov (United States)

    Asher, Robert

    2014-11-01

    New Solutions is republishing this 1991 article by Robert Asher, which reviews the history of organized labor's efforts in the United States to secure health and safety protections for workers. The 1877 passage of the Massachusetts factory inspection law and the implementation of primitive industrial safety inspection systems in many states paralleled labor action for improved measures to protect workers' health and safety. In the early 1900s labor was focusing on workers' compensation laws. The New Deal expanded the federal government's role in worker protection, supported at least by the Congress of Industrial Organizations (CIO), but challenged by industry and many members of the U.S. Congress. The American Federation of Labor (AFL) and the CIO backed opposing legal and inspection strategies in the late 1940s and through the 1950s. Still, by the late 1960s, several unions were able to help craft the Occupational Safety and Health Act of 1970 and secure new federal protections for U.S. workers.

  10. Research to support development of organic food and farming

    OpenAIRE

    Watson, Christine; Alrøe, Hugo; Kristensen, Erik Steen

    2006-01-01

    Agriculture and organic agriculture in particular are developing rapidly, due not only to technological change but also to changes in agricultural policy and public expectation. Research allows new knowledge to be developed and is thus vital for the future of organic agriculture. We can ask the question, what is the purpose of research on organic farming? Is it to increase yield and productivity, to compare it with other forms of agriculture, or to quantify its environmental and social impact...

  11. NATIONAL PAYMENT SYSTEM ORGANIZATION AND DEVELOPMENT FUNDAMENTALS

    Directory of Open Access Journals (Sweden)

    E. V. Zaytseva

    2012-01-01

    Full Text Available Rapid development of national payment systems (NPS is determined with such main factors as globalization of economic relations, application of newest information technologies, structural changes in the banking sphere and growth of the role of central banks. NPS should be considered as integral functional and institutional component of the country’s monetary system. Among main criteria that determine NPS development possibility there are its integrity, stability and flexibility. NPS may be regarded at as structure composed of the basic, organizational and regulating blocks.

  12. Origin of the water-soluble organic nitrogen in the maritime aerosol

    Science.gov (United States)

    Matsumoto, Kiyoshi; Yamamoto, Yuya; Nishizawa, Kotaro; Kaneyasu, Naoki; Irino, Tomohisa; Yoshikawa-Inoue, Hisayuki

    2017-10-01

    In order to clarify the production process for the particulate WSON in the maritime atmosphere, measurements of the WSON and the associated species in the aerosols were conducted at the coastal site on Rishiri Island near the northern tip of Japan. The mean concentration of the WSON in the aerosols was 0.077 μg m-3, which was within the previous measurements from the remote or rural clean sites. The WSON accounted for about 13% of the WSTN in the aerosols, and about 90% of the WSON was detected in the fine-mode range (d origin. The fine-mode WSON was correlated with nss-SO42- whether nss-SO42- was derived from anthropogenic or marine biogenic sources, suggesting that the WSON in the fine-mode range would be produced by the secondary processes in the acid particulate phase. EC and nss-K+, on the other hand, were not associated with the WSON in the fine-mode range, suggesting that the primary emissions from fossil fuel and/or biomass combustion are not important sources for the WSON. The coarse-mode WSON was not associated with any species. Negligible influence of dust particles and plant debris on coarse particle would cause very low concentrations of the WSON in the coarse-mode range.

  13. Origin and fate of particulate and dissolved organic matter in a naturally iron-fertilized region of the Southern Ocean

    Science.gov (United States)

    Tremblay, L.; Caparros, J.; Leblanc, K.; Obernosterer, I.

    2015-01-01

    Natural iron fertilization of high-nutrient low-chlorophyll (HNLC) waters induces annually occurring spring phytoplankton blooms off the Kerguelen Islands (Southern Ocean). To examine the origin and fate of particulate and dissolved organic matter (POM and DOM), D- and L-amino acids (AA) were quantified at bloom and HNLC stations. Total hydrolyzable AA accounted for 21-25% of surface particulate organic carbon (%POCAA) at the bloom sites, but for 10% at the HNLC site. A marked decrease in %POCAA with depth was observed at the most productive stations leading to values between 3 and 5% below 300 m depth. AA contributed to only 0.9-4.4% of dissolved organic carbon (%DOCAA) at all stations. The only consistent vertical trend was observed at the most productive station (A3-2) where %DOCAA decreased from ~ 2% in the surface waters to 0.9% near 300 m. These AA yields revealed that POM and DOM were more rapidly altered or mineralized at the bloom sites compared to the HNLC site. Alteration state was also assessed by trends in C / N ratio, %D-AA and degradation index. Different molecular markers indicated that POM mostly originated from diatoms and bacteria. The estimated average proportion of POM from intact phytoplankton cells in surface waters was 45% at the bloom station A3-2, but 14% at the HNLC site. Estimates based on D-AA yields indicated that ~ 15% of POM and ~ 30% of DOM was of bacterial origin (cells and cell fragments) at all stations. Surprisingly, the DOM in HNLC waters appeared less altered than the DOM from the bloom, had slightly higher dissolved AA concentrations, and showed no sign of alteration within the water column. Unfavorable conditions for bacterial degradation in HNLC regions can explain these findings. In contrast, large inputs of labile organic molecules and iron likely stimulate the degradation of organic matter (priming effect) and the production of more recalcitrant DOM (microbial carbon pump) during iron-fertilized blooms.

  14. Human Resource Development in Changing Organizations.

    Science.gov (United States)

    London, Manuel; Wueste, Richard A.

    This book is intended to help managers and human resource professionals understand organizational change and manage its effects on their own development and that of their subordinates. The following topics are covered in 11 chapters: organizational change, employee motivation, new managerial roles, human performance systems, upward and peer…

  15. Scrum in the Traditional Development Organization

    DEFF Research Database (Denmark)

    Ovesen, Nis; Friis Sommer, Anita

    2015-01-01

    During the last couple of years, the application of Scrum as a project management framework has been broadened from initially belonging to the software domain. Now companies within the field of traditional product development are starting to implement Scrum in an attempt to improve...

  16. Impacts of conversion of the original Brazilian cerrado vegetation in agriculture systems: changes of soil organic carbon and δ13C

    Directory of Open Access Journals (Sweden)

    Vania Rosolen

    2012-11-01

    Full Text Available The Brazilian savannah (cerrado is an area of expansion of agribusiness. Among the various environmental changes related to deforestation of the savannah stand out impacts related to soil organic matter such as the imbalances in stocks and the changing nature of soil organic carbon. The objective of these study was to evaluate changes in nature (δ13C and quantity (C% of soil carbon after conversion of the dense savannah vegetation in areas under different lan duses (pasture, soybeans, corn / soybean rotation, management (conventional and zero tillage developed in soils with different textural characteristics. The results showed that the average data set of non–managed grazing was the most distanced from the value obtained in cerrado soil. Another factor that determined the lowest concentrations of organic carbon was the presence of sandy soil. The results showed that the carbon C4 grasses in areas occupied by pastures, with or without management, replaced the original C3 carbon originated by cerrado. In the areas of conventional tillage, and no–tillage soybean, and consortium soybean/corn, no clear trend of impoverishment or enrichment of carbon and the carbon substitution as well as the incorporation of different nature of the carbon could be found.

  17. Development and implementation of methods for determination of the origin of nuclear materials

    International Nuclear Information System (INIS)

    Wallenius, M.; Pajo, L.; Mayer, K.

    2001-01-01

    The determination of the origin of seized nuclear material is important for authorities in the context of the criminal investigation, in order to return the material to its last legal owner and to help preventing any further diversion of material from this source. Origin determination is based on a complex pattern of parameters obtained through analytical measurements. The information required to determine the origin of nuclear materials may be divided into two categories: endogenous information (e.g. age or mode of production of the material) which is self-explanatory; whereas exogenous information (e.g. dimensions, surface roughness, impurities) requires a database to which the parameters can be compared. The Institute for Transuranium Elements has developed methods to determine characteristic parameters like impurities, surface roughness, or microstructural information. Furthermore, a database was set up containing relevant information on reactor fuels. (author)

  18. Origin of galaxies: a review of recent theoretical developments and their confrontation with observation

    International Nuclear Information System (INIS)

    Jones, B.J.T.

    1976-01-01

    The subject of galaxy formation has advanced considerably during the past decade. On the theoretical side two theories in particular were developed to the point where confrontation with observation will be possible; these are the ''gravitational instability picture'' and the ''cosmic turbulence theory.'' These theories are discussed at some length, with particular attention to the question of the origin of cosmic angular momentum and the nature of the initial conditions. There is now a considerable body of data on galaxies; the problem is in deciding which kind of observation is most relevant to understanding the origin of galaxies. Throughout the review an attempt is made both to put the present research in its historical perspective and to stress the possibilities for future advances towards the goal of understanding the origin of cosmic structure

  19. The interplay of biomolecules and water at the origin of the active behavior of living organisms

    International Nuclear Information System (INIS)

    Del Giudice, E; Stefanini, P; Tedeschi, A; Vitiello, G

    2011-01-01

    It is shown that the main component of living matter, namely liquid water, is not an ensemble of independent molecules but an ensemble of phase correlated molecules kept in tune by an electromagnetic (e.m) field trapped in the ensemble. This field and the correlated potential govern the interaction among biomolecules suspended in water and are in turn affected by the chemical interactions of molecules. In particular, the phase of the coherent fields appears to play an important role in this dynamics. Recent experiments reported by the Montagnier group seem to corroborate this theory. Some features of the dynamics of human organisms, as reported by psychotherapy, holistic medicine and Eastern traditions, are analyzed in this frame and could find a rationale in this context.

  20. The interplay of biomolecules and water at the origin of the active behavior of living organisms

    Science.gov (United States)

    Del Giudice, E.; Stefanini, P.; Tedeschi, A.; Vitiello, G.

    2011-12-01

    It is shown that the main component of living matter, namely liquid water, is not an ensemble of independent molecules but an ensemble of phase correlated molecules kept in tune by an electromagnetic (e.m) field trapped in the ensemble. This field and the correlated potential govern the interaction among biomolecules suspended in water and are in turn affected by the chemical interactions of molecules. In particular, the phase of the coherent fields appears to play an important role in this dynamics. Recent experiments reported by the Montagnier group seem to corroborate this theory. Some features of the dynamics of human organisms, as reported by psychotherapy, holistic medicine and Eastern traditions, are analyzed in this frame and could find a rationale in this context.

  1. Father involvement in Mexican-origin families: Preliminary development of a culturally informed measure.

    Science.gov (United States)

    Roubinov, Danielle S; Luecken, Linda J; Gonzales, Nancy A; Crnic, Keith A

    2016-04-01

    An increasing body of research has documented the significant influence of father involvement on children's development and overall well-being. However, extant research has predominately focused on middle-class Caucasian samples with little examination of fathering in ethnic minority and low-income families, particularly during the infancy period. The present study evaluated measures of early father involvement (paternal engagement, accessibility, and responsibility) that were adapted to capture important cultural values relevant to the paternal role in Mexican-origin families. A sample of 180 Mexican-origin mothers (M age = 28.3) and 83 Mexican-origin fathers (M age = 31.5) were interviewed during the perinatal period. Descriptive analyses indicated that Mexican-origin fathers are involved in meaningful levels of direct interaction with their infant. A 2-factor model of paternal responsibility was supported by factor analyses, consisting of a behavioral responsibility factor aligned with previous literature and culturally derived positive machismo factor. Qualities of the romantic relationship, cultural orientation, and maternal employment status were related to indices of father involvement. These preliminary results contribute to understanding of the transition to fatherhood among low-income Mexican-origin men and bring attention to the demographic, social, and cultural contexts in which varying levels of father involvement may emerge. (c) 2016 APA, all rights reserved).

  2. Father involvement in Mexican origin families: Preliminary development of culturally-informed measure

    Science.gov (United States)

    Roubinov, Danielle S.; Luecken, Linda J.; Gonzales, Nancy A.; Crnic, Keith A.

    2015-01-01

    Objectives An increasing body of research has documented the significant influence of father involvement on children’s development and overall well-being. However, extant research has predominately focused on middle-class Caucasian samples with little examination of fathering in ethnic minority and low-income families, particularly during the infancy period. The present study evaluated measures of early father involvement (paternal engagement, accessibility, and responsibility) that were adapted to capture important cultural values relevant to the paternal role in Mexican origin families. Methods A sample of 180 Mexican origin mothers (M age = 28.3) and 83 Mexican origin fathers (M age = 31.5) were interviewed during the perinatal period. Results Descriptive analyses indicated that Mexican origin fathers are involved in meaningful levels of direct interaction with their infant. A two-factor model of paternal responsibility was supported by factor analyses, consisting of a behavioral responsibility factor aligned with previous literature and culturally-derived positive machismo factor. Qualities of the romantic relationship, cultural orientation, and maternal employment status were related to indices of father involvement. Conclusions These preliminary results contribute to understanding of the transition to fatherhood among low-income Mexican origin men and bring attention to the demographic, social, and cultural contexts in which varying levels of father involvement may emerge. PMID:26237543

  3. The System Dynamics Model for Development of Organic Agriculture

    Science.gov (United States)

    Rozman, Črtomir; Škraba, Andrej; Kljajić, Miroljub; Pažek, Karmen; Bavec, Martina; Bavec, Franci

    2008-10-01

    Organic agriculture is the highest environmentally valuable agricultural system, and has strategic importance at national level that goes beyond the interests of agricultural sector. In this paper we address development of organic farming simulation model based on a system dynamics methodology (SD). The system incorporates relevant variables, which affect the development of the organic farming. The group decision support system (GDSS) was used in order to identify most relevant variables for construction of causal loop diagram and further model development. The model seeks answers to strategic questions related to the level of organically utilized area, levels of production and crop selection in a long term dynamic context and will be used for simulation of different policy scenarios for organic farming and their impact on economic and environmental parameters of organic production at an aggregate level.

  4. Characterization and origin of organic and inorganic pollution in urban soils in Pisa (Tuscany, Italy).

    Science.gov (United States)

    Cardelli, Roberto; Vanni, Giacomo; Marchini, Fausto; Saviozzi, Alessandro

    2017-10-12

    We assessed the quality of 31 urban soils in Pisa by analyzing total petroleum hydrocarbons (TPHs), Cd, Cr, Cu, Hg, Mn, Ni, Pb, Zn, and the platinum group elements (PGEs). The risk was evaluated by the geological accumulation index (I geo ) and the enrichment factor (EF). Results were compared with those obtained from a non-urban site and with the quantitative limits fixed by Italian legislation. In nearly all the monitored sites, the legal limit for TPH of 60 mg/kg in residential areas was exceeded, indicating widespread and intense pollution throughout the entire city area. The I geo indicated no Cd, Cu, Mn, Ni, and Zn pollution and minimal Pb and Cr pollution due to anthropogenic enrichment. Legal Hg and Zn limits of 1 and 150 mg/kg, respectively, were exceeded in about 20% of sites; Cd (2 mg/kg), Cr (150 mg/kg), and Cu (120 mg/kg) in only one site; and the Ni legal limit of 120 mg/kg was never exceeded. Some urban soils showed a higher Hg level than the more restrictive legal limit of 5 mg/kg concerning areas for industrial use. Based on the soluble, exchangeable, and carbonate-bound fractions, Mn and Zn showed the highest mobility, suggesting a more potential risk of soil contamination than the other metals. The TPH and both Cr and Hg amounts were not correlated with any of the other monitored metals. The total contents of Cd, Pb, Zn, and Cu in soils were positively correlated with each other, suggesting a common origin from vehicular traffic. The PGE values (Pt and Pd) were below the detection limits in 75%-90% of the monitored areas, suggesting that their accumulation is at an early stage.

  5. Origin of unusual bandgap shift and dual emission in organic-inorganic lead halide perovskites.

    Science.gov (United States)

    Dar, M Ibrahim; Jacopin, Gwénolé; Meloni, Simone; Mattoni, Alessandro; Arora, Neha; Boziki, Ariadni; Zakeeruddin, Shaik Mohammed; Rothlisberger, Ursula; Grätzel, Michael

    2016-10-01

    Emission characteristics of metal halide perovskites play a key role in the current widespread investigations into their potential uses in optoelectronics and photonics. However, a fundamental understanding of the molecular origin of the unusual blueshift of the bandgap and dual emission in perovskites is still lacking. In this direction, we investigated the extraordinary photoluminescence behavior of three representatives of this important class of photonic materials, that is, CH 3 NH 3 PbI 3 , CH 3 NH 3 PbBr 3 , and CH(NH 2 ) 2 PbBr 3 , which emerged from our thorough studies of the effects of temperature on their bandgap and emission decay dynamics using time-integrated and time-resolved photoluminescence spectroscopy. The low-temperature (photoluminescence of CH 3 NH 3 PbI 3 and CH 3 NH 3 PbBr 3 reveals two distinct emission peaks, whereas that of CH(NH 2 ) 2 PbBr 3 shows a single emission peak. Furthermore, irrespective of perovskite composition, the bandgap exhibits an unusual blueshift by raising the temperature from 15 to 300 K. Density functional theory and classical molecular dynamics simulations allow for assigning the additional photoluminescence peak to the presence of molecularly disordered orthorhombic domains and also rationalize that the unusual blueshift of the bandgap with increasing temperature is due to the stabilization of the valence band maximum. Our findings provide new insights into the salient emission properties of perovskite materials, which define their performance in solar cells and light-emitting devices.

  6. Origin, composition and quality of suspended particulate organic matter in relation to freshwater inflow in a South Texas estuary

    Science.gov (United States)

    Lebreton, Benoit; Beseres Pollack, Jennifer; Blomberg, Brittany; Palmer, Terence A.; Adams, Leslie; Guillou, Gaël; Montagna, Paul A.

    2016-03-01

    South Texas has a semi-arid climate with a large interannual variability of freshwater inflows. This study sought to define how changes in freshwater inflow affect the composition, quantity and quality of suspended particulate organic matter (SPOM) in a South Texas estuary: the Mission-Aransas estuary. The study was implemented 1.5 months after a large rain event in September 2010 and continued for 10 months of drought conditions. The composition of SPOM originating from rivers, the Gulf of Mexico and the estuary were determined using stable isotopes (δ13C, δ15N and δ34S). The quantity and quality of SPOM were assessed using organic carbon content, chlorophyll a concentrations and C/chl a ratios. Our results demonstrated that autochthonous phytoplankton was the dominant component of SPOM in the Mission-Aransas estuary during droughts. Benthic organic matter from local primary producers (i.e., seagrass, salt marsh plants, benthic microalgae) did not influence SPOM composition, either as fresh material or as detritus. A comparison with a positive estuary (i.e., Sabine-Neches estuary, TX) indicates that decreases in freshwater inflow may lead to decreases of terrestrial organic matter inputs and to increase the ratio of autochtonous phytoplanktonic material in SPOM.

  7. Extraterrestrial organic chemistry: from the interstellar medium to the origins of life. Part 2: complex organic chemistry in the environment of planets and satellites.

    Science.gov (United States)

    Raulin, F; Kobayashi, K

    2001-01-01

    During COSPAR'00 in Warsaw, Poland, in the frame of Sub-Commission F.3 events (Planetary Biology and Origins of Life), part of COSPAR Commission F (Life Sciences as Related to Space), and Commission B events (Space Studies of the Earth-Moon System, Planets, and Small Bodies of the Solar System) a large joint symposium (F.3.4/B0.8) was held on extraterrestrial organic chemistry. Part 2 of this symposium was devoted to complex organic chemistry in the environment of planets and satellites. The aim of this event was to cover and review new data which have been recently obtained and to give new insights on data which are expected in the near future to increase our knowledge of the complex organic chemistry occurring in several planets and satellites of the Solar System, outside the earth, and their implications for exobiology and life in the universe. The event was composed of two main parts. The first part was mainly devoted to the inner planets and Europa and the search for signatures of life or organics in those environments. The second part was related to the study of the outer solar system.

  8. Genomic Analyses Reveal the Influence of Geographic Origin, Migration, and Hybridization on Modern Dog Breed Development

    Directory of Open Access Journals (Sweden)

    Heidi G. Parker

    2017-04-01

    Full Text Available There are nearly 400 modern domestic dog breeds with a unique histories and genetic profiles. To track the genetic signatures of breed development, we have assembled the most diverse dataset of dog breeds, reflecting their extensive phenotypic variation and heritage. Combining genetic distance, migration, and genome-wide haplotype sharing analyses, we uncover geographic patterns of development and independent origins of common traits. Our analyses reveal the hybrid history of breeds and elucidate the effects of immigration, revealing for the first time a suggestion of New World dog within some modern breeds. Finally, we used cladistics and haplotype sharing to show that some common traits have arisen more than once in the history of the dog. These analyses characterize the complexities of breed development, resolving longstanding questions regarding individual breed origination, the effect of migration on geographically distinct breeds, and, by inference, transfer of trait and disease alleles among dog breeds.

  9. Newly developed standard reference materials for organic contaminant analysis

    Energy Technology Data Exchange (ETDEWEB)

    Poster, D.; Kucklick, J.; Schantz, M.; Porter, B.; Wise, S. [National Inst. of Stand. and Technol., Gaithersburg, MD (USA). Center for Anal. Chem.

    2004-09-15

    The National Institute of Standards and Technology (NIST) has issued a number of Standard Reference Materials (SRM) for specified analytes. The SRMs are biota and biological related materials, sediments and particle related SRMs. The certified compounds for analysis are polychlorinated biphenyls (PCB), polycylic aromatic hydrocarbons (PAH) and their nitro-analogues, chlorinated pesticides, methylmercury, organic tin compounds, fatty acids, polybrominated biphenyl ethers (PBDE). The authors report on origin of materials and analytic methods. (uke)

  10. Magnetic resonance imaging (MRI) of liver and brain in haematologic-organic patients with fever of unknown origin

    International Nuclear Information System (INIS)

    Heussel, C.P.; Kauczor, H.U.; Poguntke, M.; Schadmand-Fischer, S.; Mildenberger, P.; Thelen, M.; Heussel, G.

    1998-01-01

    To examine the advantage of liver and brain MRI in clinically anomalous haematological patients with fever of unknown origin. Material and Methods: Twenty liver MRI (T 2 -TSE, T 2 -HASTE, T 1 -FLASH±Gd dynamic) and 16 brain MRI (T 2 -TSE, FLAIR, T 1 -TSE±Gd) were performed searching for a focus of fever with a suspected organ system. Comparison with clinical follow-up. Results: suspected organ system. Comparison with clinical follow-up. Results: A focus was detected in 11/20 liver MRI. Candidiasis (n=3), mycobacteriosis (n=2), relapse of haematological disease (n=3), graft versus host disease (n=1), non-clarified (n=2). The remaining 9 cases with normal MRI were not suspicious of infectious hepatic disease during follo-wup. In brain MRI, 3/16 showed a focus (toxoplasmosis, aspergillosis, mastoiditis). Clinical indication for an infectious involvement of the brain was found in 4/16 cases 2--5 months after initially normal brain MRI. No suspicion of an infectious involvement of brain was present in the remaining 9/16 cases. Conclusion: In case of fever of unknown origin and suspicion of liver involvement, MRI of the liver should be performed due to data given in literature and its sensitivity of 100%. Because of the delayed detectability of cerebral manifestations, in cases of persisting suspicion even a previously normal MRI of the brain should be repeated. (orig.) [de

  11. Original article The regulative function of mentalization and mindfulness in borderline personality organization

    Directory of Open Access Journals (Sweden)

    Monika Marszał

    2015-03-01

    Full Text Available Background The aim of this study was to broaden the understanding of the emotional difficulties of borderline personality organization (BPO by reference to a meta-ability named ‘orientation on the internal world’, here conceptualized as mentalization and mindfulness, in the framework of object relation theory. It was assumed that it is not mentalization “in itself”, but mainly its regulatory function, that is important for BPO. Participants and procedure The clinical and control groups (30 individuals each were examined using The Mental States Task, The Difficulties of Emotion Regulation Scale and The Mindful Attention Awareness Scale. Results Individuals with BPO functioned worse than the control group in terms of mentalization, mindfulness, and emotion regulation. The relationship between BPO and the meta-abilities was mediated by emotional dysregulation: total mediation was revealed for one mentalization dimension, and partial mediation was observed for mindfulness. Conclusions Orientation on emotional experience and emotional dysregulation are not independent predictors of BPO, but they can be treated as levels in the hierarchical model. Mentalization determines and influences emotion regulation in BPO.

  12. Chromatin Structure and Replication Origins: Determinants Of Chromosome Replication And Nuclear Organization

    Science.gov (United States)

    Smith, Owen K.; Aladjem, Mirit I.

    2014-01-01

    The DNA replication program is, in part, determined by the epigenetic landscape that governs local chromosome architecture and directs chromosome duplication. Replication must coordinate with other biochemical processes occurring concomitantly on chromatin, such as transcription and remodeling, to insure accurate duplication of both genetic and epigenetic features and to preserve genomic stability. The importance of genome architecture and chromatin looping in coordinating cellular processes on chromatin is illustrated by two recent sets of discoveries. First, chromatin-associated proteins that are not part of the core replication machinery were shown to affect the timing of DNA replication. These chromatin-associated proteins could be working in concert, or perhaps in competition, with the transcriptional machinery and with chromatin modifiers to determine the spatial and temporal organization of replication initiation events. Second, epigenetic interactions are mediated by DNA sequences that determine chromosomal replication. In this review we summarize recent findings and current models linking spatial and temporal regulation of the replication program with epigenetic signaling. We discuss these issues in the context of the genome’s three-dimensional structure with an emphasis on events occurring during the initiation of DNA replication. PMID:24905010

  13. Origin of Non-Radiative Voltage Losses in Fullerene-Based Organic Solar Cells

    Science.gov (United States)

    Benduhn, Johannes; Tvingstedt, Kristofer; Piersimoni, Fortunato; Ullbrich, Sascha; Neher, Dieter; Spoltore, Donato; Vandewal, Koen

    The open-circuit voltage of organic solar cells (OSCs) is low as compared to the optical gap of the absorber molecules, indicating high energy losses per absorbed photon. These voltage losses arise only partly due to necessity of an electron transfer event to dissociate the excitons. A large part of these voltage losses is due to recombination of photo-generated charge carriers, including inevitable radiative recombination. In this work, we study the non-radiative recombination losses and we find that they increase when the energy difference between charge transfer (CT) state and ground state decreases. This behavior is in agreement with the \\x9Denergy gap law for non-radiative transition\\x9D, which implies that internal conversion from CT state to ground state is facilitated by skeletal molecular vibrations. This intrinsic loss mechanism, which until now has not been thoroughly considered for OSCs, is different in its nature as compared to the commonly considered inorganic photovoltaic loss mechanisms of defect, surface, and Auger recombination. As a consequence, the theoretical upper limit for the power conversion efficiency of a single junction OSC reduces by 25% as compared to the Shockley-Queisser limit for an optimal optical gap of the main absorber between (1.45-1.65) eV.

  14. Current Situations and Countermeasures of Organic Tobacco Development

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Current situations of organic tobacco development at both home and abroad,indicating that organic tobacco is one of the innovation directions for sustainable,healthy,environmental protection and low carbon development of modern tobacco industry.On the basis of foreign cultivation technical system for organic agriculture,the cultivation technical system for organic tobacco is summed up as follows:first,keep the diversity and continuity of space and time;second,ensure closeness of nutrient cycle;third,improve self-regulatory system and protection ability of crops.Then,the development trend of organic tobacco is analyzed and corresponding measures are put forward:establish production base and assessment system for organic tobacco;establish technical system for production of organic tobacco;establish and perfect evaluation system for management,production and supervision of organic tobacco;strengthen popularization of production and concept of organic tobacco;improve management of organic tobacco purchase,industry commerce handover,and redrying.

  15. Developing ethical competence in health care organizations.

    Science.gov (United States)

    Kälvemark Sporrong, Sofia; Arnetz, Bengt; Hansson, Mats G; Westerholm, Peter; Höglund, Anna T

    2007-11-01

    Increased work complexity and financial strain in the health care sector have led to higher demands on staff to handle ethical issues. These demands can elicit stress reactions, that is, moral distress. One way to support professionals in handling ethical dilemmas is education and training in ethics. This article reports on a controlled prospective study evaluating a structured education and training program in ethics concerning its effects on moral distress. The results show that the participants were positive about the training program. Moral distress did not change significantly. This could be interpreted as competence development, with no effects on moral distress. Alternatively, the result could be attributed to shortcomings of the training program, or that it was too short, or it could be due to the evaluation instrument used. Organizational factors such as management involvement are also crucial. There is a need to design and evaluate ethics competence programs concerning their efficacy.

  16. Acidity and origin of dissolved organic carbon in different vegetation zones

    Science.gov (United States)

    Hruška, Jakub; Oulehle, Filip; Myška, Oldřích; Chuman, Tomáš

    2016-04-01

    The acid/base character of aquatic dissolved organic carbon (DOC) has been studied intensively during recent decades with regard to the role of DOC in stream water acidity and the balance between natural acidity and anthropogenic acidification. Recently, DOC has been shown to play an important role in preindustrial surface waters. Studies focused on the acid/base properties of DOC have been carried out in mainly in Europe and North America and paint a conflicting picture. Some studies reported large differences in acid base properties, sometimes between quite similar and nearby localities, or between seasons at the same site. Other studies, however, found similar acid/base properties in waters from a variety of sites, sometimes far from each other as well as stable acid/base properties at the same site through different seasons or runoff events. Site density of DOC (amount of carboxylic groups per milligram of DOC) and SUVA was measured for streams (or small tundra ponds respectively) from the tundra in northern Alaska, boreal zone of Sweden, western Czech Republic (temperate region), and tropical Congo rain forest in central Africa. At least 10 samples from each region were taken from surface waters during the growing season. Titration of carboxylic groups after proton saturation on cation-exchange resin was used for site density determination. Despite very different climatic and vegetation properties and internal variation within a region, there was no statistically significant difference among regions for site density (it varied between 10.2-10.5 ueq/mg DOC) as well as for SUVA (tested by ANOVA). Results suggest that different vegetation and climate produced generally the same DOC in respect of acid/base character and SUVA. It also suggests that use of the one analytical technique was more important than differences between climatic zones itself.

  17. Understanding the origins of metal-organic framework/polymer compatibility.

    Science.gov (United States)

    Semino, R; Moreton, J C; Ramsahye, N A; Cohen, S M; Maurin, G

    2018-01-14

    The microscopic interfacial structures for a series of metal-organic framework/polymer composites consisting of the Zr-based UiO-66 coupled with different polymers are systematically explored by applying a computational methodology that integrates density functional theory calculations and force field-based molecular dynamics simulations. These predictions are correlated with experimental findings to unravel the structure-compatibility relationship of the MOF/polymer pairs. The relative contributions of the intermolecular MOF/polymer interactions and the flexibility/rigidity of the polymer with respect to the microscopic structure of the interface are rationalized, and their impact on the compatibility of the two components in the resulting composite is discussed. The most compatible pairs among those investigated involve more flexible polymers, i.e. polyvinylidene fluoride (PVDF) and polyethylene glycol (PEG). These polymers exhibit an enhanced contact surface, due to a better adaptation of their configuration to the MOF surface. In these cases, the irregularities at the MOF surface are filled by the polymer, and even some penetration of the terminal groups of the polymer into the pores of the MOF can be observed. As a result, the affinity between the MOF and the polymer is very high; however, the pores of the MOF may be sterically blocked due to the strong MOF/polymer interactions, as evidenced by UiO-66/PEG composites. In contrast, composites involving polymers that exhibit higher rigidity, such as the polymer of intrinsic microporosity-1 (PIM-1) or polystyrene (PS), present interfacial microvoids that contribute to a decrease in the contact surface between the two components, thus reducing the MOF/polymer affinity.

  18. SPECIFIC FEATURES OF DEVELOPMENT OF ORGANIC PRODUCTS MARKET IN UKRAINE

    Directory of Open Access Journals (Sweden)

    T. Kharchenko

    2013-08-01

    Full Text Available The article is dedicated to the development of new and improvement of existing theoretical and methodological basis of forming and developing the market of organic products, its correspondence to the present-day situation, determination of problems and ways of their solving, introduction in practical activity of Ukrainian enterprises. The main objective of the article is to determine the specific features of forming and developing organic products market in Ukraine, and the perspective directions of its development based on analysis and practice of functioning of such markets in the world. The environmentally sound products market in the world is being analyzed, some information on the countries with the most commodity turnover of organic products, structure of international market of organic products, volumes of sales of organic products in the European countries is provided. As a result of studying the modern trends of economic development the authors reach a conclusion on problems of standard introduction, investigate the European norms and requirements for organic products. The conducted research allows distinguishing the basic features of Ukrainian market of organic products: it quickly grows, which makes it especially appealing for the participants of market relations, however entry into this market requires considerable capital investments and is characterized by high risk; criteria for qualifying products as environmentally sound products are unstructured and unclear. The potential for growth of organic products market in Ukraine is examined.

  19. Traditional products: Base for the sustainable development of Serbian animal origin products

    Directory of Open Access Journals (Sweden)

    Stevanović Jasna Lj.

    2016-01-01

    Full Text Available Research results on the diversity of traditional products of animal origin from certain areas of the Republic of Serbia, provides an opportunity to become part of the sustainable quality development, which would be based on their promotion and protection of local resources. Traditional products of animal origin are different and inseparable from the local identity, typical for nation and its food culture. Through confidence-building, and protection from oblivion, the value of domestic products, had preserved trough centuries-old tradition. Nowadays, each domestic product has its own recognisable taste, representing climate of the Republic of Serbia, from which it comes. Universally accepted model of rural institutional structure does not exist. Instead it accommodates and develops in accordance to needs, possibilities and area specific characteristics. By the efficient protection rural models becomes an investment incentives and contribute to general economic and industrial prosperity of the society.

  20. Development of Organ-Specific Donor Risk Indices

    OpenAIRE

    Akkina, Sanjeev K.; Asrani, Sumeet K.; Peng, Yi; Stock, Peter; Kim, Ray; Israni, Ajay K.

    2012-01-01

    Due to the shortage of deceased donor organs, transplant centers accept organs from marginal deceased donors, including older donors. Organ-specific donor risk indices have been developed to predict graft survival using various combinations of donor and recipient characteristics. We will review the kidney donor risk index (KDRI) and liver donor risk index (LDRI) and compare and contrast their strengths, limitations, and potential uses. The Kidney Donor Risk Index has a potential role in devel...

  1. De novo formation of nucleoli in developing mouse embryos originating from enucleolated zygotes.

    Science.gov (United States)

    Kyogoku, Hirohisa; Fulka, Josef; Wakayama, Teruhiko; Miyano, Takashi

    2014-06-01

    The large, compact oocyte nucleoli, sometimes referred to as nucleolus precursor bodies (NPBs), are essential for embryonic development in mammals; in their absence, the oocytes complete maturation and can be fertilized, but no nucleoli are formed in the zygote or embryo, leading to developmental failure. It has been convincingly documented that zygotes inherit the oocyte nucleolar material and form NPBs again in pronuclei. It is commonly accepted that during early embryonic development, the original compact zygote NPBs gradually transform into reticulated nucleoli of somatic cells. Here, we show that zygote NPBs are not required for embryonic and full-term development in the mouse. When NPBs were removed from late-stage zygotes by micromanipulation, the enucleolated zygotes developed to the blastocyst stage and, after transfer to recipients, live pups were obtained. We also describe de novo formation of nucleoli in developing embryos. After removal of NPBs from zygotes, they formed new nucleoli after several divisions. These results indicate that the zygote NPBs are not used in embryonic development and that the nucleoli in developing embryos originate from de novo synthesized materials. © 2014. Published by The Company of Biologists Ltd.

  2. The Development of Customary International Law by International Organizations

    DEFF Research Database (Denmark)

    Odermatt, Jed

    2017-01-01

    In his Fourth Report on the Identification of Customary International Law (2016), Special Rapporteur Michael Wood confirmed that ‘[i]n certain cases, the practice of international organizations also contributes to the expression, or creation, of rules of customary international law.......’ That the practice of international organizations can be relevant when identifying customary international law is relatively uncontroversial. The practice of states within international organizations such as the UN General Assembly, for example, may contribute to the development of custom. Yet, there is little...... discussion about whether and how the practice of international organizations as such may contribute to the development of customary international law. This contribution discusses the organization that is the most capable of contributing to the development of customary international law in its own right...

  3. Natural isotopic composition of nitrogen as a tracer of origin for suspended organic matter in the Scheldt estuary

    International Nuclear Information System (INIS)

    Mariotti, A.; Lancelot, C.; Billen, G.

    1984-01-01

    The natural isotopic composition of suspended particulate organic nitrogen was determined in the Southern Bight of the North Sea and in the Scheldt estuary. These data show that delta 15 N constitutes a convenient tracer of the origin of the suspended matter. In the winter, in the absence of intensive primary production, the suspended organic matter of the Scheldt estuary is a mixture of two components: a continental detrital component characterized by a low delta value of 1.5per mille and a marine component with a mean delta value of 8per mille. During the phytoplankton flowering period, lasting from early May to October, intensive primary production occurs throughout the estuary giving rise to a third source of organic matter. This material is characterized by high delta values reflecting the isotopic composition of ammonia, the nitrogenous nutrient assimilated by phytoplankton in the estuary. The nitrification process occuring in the mixing area of the Scheldt estuary leads to higher downstream delta values of ammonia (> 20per mille) which permits the distinction between estuarine from fresh-water phytoplankton. Simple isotopic budget calculations show that, both in the upstream part and in the downstream part, autochthonous phytoplanktonic material contributes a major part of the total suspended matter in the Scheldt estuary during summer. (author)

  4. Organic marketing initiatives and rural development - lessons learned for the organic industry

    DEFF Research Database (Denmark)

    Kristensen, Niels Heine; Kujala, Jouni

    2005-01-01

    Kujala J, Kristensen NH, (2005): Organic marketing initiatives and rural development - lessons learned for the organic industry. Article in "Organic farming for a new millennium - status and future challenges". Published by Nordic Association of Agricultural Scientists (NJF). Swedish University...... of Agricultural Sciences Alnarp, Sweden. NJF-Seminar 369, June 15-17, 2005. Electronic version available at www.njf.nu. ISSN 1653-2015...

  5. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    language in social interaction( Anto et al., 2012; Tessema et al., 2012). While such ..... 10 items on a five-point Likert scale originally developed by Benard et al. (2007). ..... self-confidence, and hold down their anxiety levels. In this study ...

  6. Teacher Activist Organizations and the Development of Professional Agency

    Science.gov (United States)

    Quinn, Rand; Carl, Nicole Mittenfelner

    2015-01-01

    Teacher professional agency refers to the ability of teachers to control their work within structural constraints. In this paper, we show how teacher activist organizations can assist in the development of professional agency. We focus on a teacher activist organization in a large urban district in the United States and identify three…

  7. Student Organizations as Avenues for Leader Learning and Development.

    Science.gov (United States)

    Sessa, Valerie I; Alonso, Nicole; Farago, Pamela; Schettino, Gaynell; Tacchi, Kelcie; Bragger, Jennifer D

    2017-09-01

    This chapter describes theory and research demonstrating that the experiences students have within student organizations, and the people with whom they interact within those organizations, are powerful triggers for leader learning and development. © 2017 Wiley Periodicals, Inc., A Wiley Company.

  8. The Significance of Student Organizations to Leadership Development.

    Science.gov (United States)

    Rosch, David M; Collins, Jasmine D

    2017-09-01

    Student organizations have existed for almost as long as educational institutions have. This chapter examines the historical role of student organizations in developing leadership capacity in students, as well as their current roles on high school and collegiate campuses in creating transformational environments for student leadership learning and growth. © 2017 Wiley Periodicals, Inc., A Wiley Company.

  9. Use of Graphic Organizers in a Language Teachers' Professional Development

    Science.gov (United States)

    Chien, Chin-Wen

    2012-01-01

    Starting from 2009 academic year, the instructional coaches in a school district in a northwest American city began to provide Workshop II (pseudonym) to elementary school English teachers. This study aims to discuss the use of graphic organizers in English teachers' professional development. Different types of graphic organizers such as…

  10. Life and understanding:the origins of ‘understanding’ in self-organizing nervous systems.

    Directory of Open Access Journals (Sweden)

    Yan Mark Yufik

    2016-12-01

    Full Text Available This article is motivated by the formulation of biotic self-organisation in (Friston, 2013, where the emergence of ‘life’ in coupled material entities (e.g., macromolecules was predicated on bounded subsets that maintain a degree of statistical independence from the rest of the network. Boundary elements in such systems or units constitute a Markov blanket; separating the internal states of the unit from its surrounding states. In this paper, we ask whether Markov blankets operate in the nervous system and underlie the development of intelligence, enabling a progression from the ability to sense the environment to the ability to understand it. Markov blankets have been previously hypothesized to form in neuronal networks as a result of phase transitions that cause network subsets to fold into bounded assemblies, or packets (Yufik, 1998a. The ensuing neuronal packets hypothesis builds on the notion of neuronal assemblies (Hebb, 1949, 1980, treating such assemblies as flexible but stable biophysical structures capable of withstanding entropic erosion. In other words, structures that maintain their integrity under changing conditions. In this treatment, neuronal packets give rise to perception of ’objects’; i.e., quasi-stable (stimulus bound groupings that are conserved over multiple presentations (e.g., the experience of perceiving ‘apple’ can be interrupted and resumed many times. Monitoring the variations in such groups enables the apprehension of behaviour; i.e., attributing to objects the ability to undergo changes without loss of self-identity. Ultimately, ‘understanding’ involves self-directed composition and manipulation of the ensuing ‘mental models’ that are constituted by neuronal packets, whose dynamics capture relationships among objects: that is, dependencies in the behaviour of objects under varying conditions. For example, movement is known to involve rotation of population vectors in the motor cortex

  11. THE FORMATION AND DEVELOPMENT OF CORPORATE CULTURE OF THE MEDICAL ORGANIZATIONS

    Directory of Open Access Journals (Sweden)

    O. L. Zadvornaya

    2016-01-01

    Full Text Available The article is devoted to the problem of formation and development of corporate culture as the main factor of the successful functioning of medical organization in terms of optimization of activity of the health system. Discusses the importance and main directions of development of corporate culture for personal and organizational development. The authors identified features of the corporate culture of healthcare organizations, the approaches, showing the sequence and contents of the main practical activities on the formation, maintenance and development of corporate culture. Emphasized the need for further research and introduction of corporate culture and cultural values in health care organizations. Purpose/ objectives: to Study and evaluate the corporate culture of healthcare organizations to improve institutional management and increase of efficiency activity of medical organizations. Materials and methods: For data collection methods were used: direct observation, interviews, questionnaires. In conducting this study used data from official sources, a literature review, a systematic approach, comparative analysis, historical, sociological, statistical research methods. The results of the study indicate the need for concept development, tools implementation and development of corporate culture in the practice of the medical organizations.Conclusions/Significance: Corporate culture – the system of collectively shared values, symbols, beliefs, standards of behaviour employees of the organization that contributes to the originality and uniqueness of the activities of medical organizations that promote the identification of employees with the organization; Corporate culture is formed with the influence of factors external and internal environment of the organization, solving problems, external adaptation  and internal integration in the environment; Generated and promoted by the corporate culture is an important management tool, creates

  12. Alternative splicing originates different domain structure organization of Lutzomyia longipalpis chitinases.

    Science.gov (United States)

    Ortigão-Farias, João Ramalho; Di-Blasi, Tatiana; Telleria, Erich Loza; Andorinho, Ana Carolina; Lemos-Silva, Thais; Ramalho-Ortigão, Marcelo; Tempone, Antônio Jorge; Traub-Csekö, Yara Maria

    2018-02-01

    BACKGROUND The insect chitinase gene family is composed by more than 10 paralogs, which can codify proteins with different domain structures. In Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil, a chitinase cDNA from adult female insects was previously characterized. The predicted protein contains one catalytic domain and one chitin-binding domain (CBD). The expression of this gene coincided with the end of blood digestion indicating a putative role in peritrophic matrix degradation. OBJECTIVES To determine the occurrence of alternative splicing in chitinases of L. longipalpis. METHODS We sequenced the LlChit1 gene from a genomic clone and the three spliced forms obtained by reverse transcription polymerase chain reaction (RT-PCR) using larvae cDNA. FINDINGS We showed that LlChit1 from L. longipalpis immature forms undergoes alternative splicing. The spliced form corresponding to the adult cDNA was named LlChit1A and the two larvae specific transcripts were named LlChit1B and LlChit1C. The B and C forms possess stop codons interrupting the translation of the CBD. The A form is present in adult females post blood meal, L4 larvae and pre-pupae, while the other two forms are present only in L4 larvae and disappear just before pupation. Two bands of the expected size were identified by Western blot only in L4 larvae. MAIN CONCLUSIONS We show for the first time alternative splicing generating chitinases with different domain structures increasing our understanding on the finely regulated digestion physiology and shedding light on a potential target for controlling L. longipalpis larval development.

  13. Comparative Analysis of the Effects of Organization Development ...

    African Journals Online (AJOL)

    Comparative Analysis of the Effects of Organization Development Interventions on Organizational Leadership and Management Practice: A Case Of Green Earth Program (GEP) ... Journal of Language, Technology & Entrepreneurship in Africa.

  14. World Trade Organization Negotiations: The Doha Development Agenda

    National Research Council Canada - National Science Library

    Fergusson, Ian F

    2008-01-01

    The World Trade Organization's (WTO) Doha Development Round of multilateral trade negotiations resumed in 2007 after being suspended in July 2006 after key negotiating groups failed to break a deadlock on agricultural tariffs and subsidies...

  15. Developing the Practice of Organization Design in Arts Management Education

    NARCIS (Netherlands)

    Kolsteeg, Johan

    2013-01-01

    This research contributes to the development of organization design, interpreted as the use of creative processes in solving organizational dilemmas, specifically the element of project management. Looking at problem articulation, process variabality, prototyping and commissionership from a design

  16. INNOVATION - A STRATEGIC RESOURCE FOR THE DEVELOPMENT OF BUSINESS ORGANIZATIONS

    Directory of Open Access Journals (Sweden)

    V. L. Polyakov

    2012-01-01

    Full Text Available This paper discusses issues arising from the need to translate the Russian economy to innovative development. Essence and meaning of concepts such as innovation, innovation process, innovation management solution, the investment in relation to business organizations.

  17. Development of a Soil Organic Carbon Baseline for Otjozondjupa, Namibia

    OpenAIRE

    Nijbroek, R.; Kempen, B.; Mutua, J.; Soderstrom, M.; Piikki, K.; Hengari, S.; Andreas, A.

    2017-01-01

    Land Degradation Neutrality (LDN) has been piloted in 14 countries and will be scaled up to over 120 countries. As a LDN pilot country, Namibia developed sub-national LDN baselines in Otjozondjupa Region. In addition to the three LDN indicators (soil organic carbon, land productivity and land cover change), Namibia also regards bush encroachment as an important form of land degradation. We collected 219 soil profiles and used Random Forest modelling to develop the soil organic carbon stock ba...

  18. GENESIS OF METHODOLOGY OF MANAGEMENT BY DEVELOPMENT OF ORGANIZATIONS

    Directory of Open Access Journals (Sweden)

    Z.N. Varlamova

    2007-06-01

    Full Text Available In clause the genesis of methodology of management of development of organizations as sets of the used methodological approaches and methods is investigated. The results of the comparative analysis of the methodological approaches to management of organizational development are submitted. The traditional methodological approaches are complemented strategic experiment and methodology case studies. The approaches to formation of new methodology and technique of research of sources of competitive advantages of organization are considered.

  19. The Roles of Knowledge Management for the Development of Organizations

    OpenAIRE

    Mohajan, Haradhan

    2017-01-01

    Knowledge is the most important factor of production, next to labor, land and capital. It is about managing and sharing knowledge for the development of an organization. In the competitive business world, knowledge management (KM) has become more essential for the sustainable development of organizations. In the 21st century knowledge and KM become the most professional element in many fields of knowledge, such as, education, cognitive science, health, sociology, management science, informati...

  20. Isotopic methods for identifying the origin of metal and organic pollutants in the environment: state of the art and critical approach for implementation. Extended abstract

    International Nuclear Information System (INIS)

    Negrel, Ph.

    2011-06-01

    Pollutants identification in media like water, soils and air has been greatly improved with the development of new analytical apparatus like ICP-MS, ICP-MS-MC, GC-MS, GC/IRMS... Contents and behavior of metals are now more known and constrained due to the multi element analysis by ICP-MS. In the frame of pollutants origin studies, numerous tricky questions can thus be answered by coupling metal contents in association with their isotope composition, in particular due to the development of ICP-MS-MC. On the other hand, soils and groundwater pollution by major organic compounds (COV, HAP) represents an increasing problem and classical approaches, mainly based on the contents monitoring are limited. As for metals, these limitations can be overwhelmed by coupling with isotope tracing. The first outcome of this study is the present day view of the whole set of studies carried out and published by the scientific community in the frame of the isotope tracing approach for characterizing organic molecules and metals pollution over a limited number of each. This study also highlighted the benefits of the isotopic tracing in the characterization and the back tracing of pollution sources in the organic molecules degradation processes. (author)

  1. Formation of modern theoretical regulations about organization concerning management development

    Directory of Open Access Journals (Sweden)

    Zhalinska I.V.

    2017-03-01

    Full Text Available The article deals with the scientific concepts about an organization as the entity of management concerning management development. The author studies the principal theoretical regulations about an organization within the most spread schools of management and context of development of other managerial concepts in particular, strategic management. It is found out that an organization and its development had not considered as the factor of an effective activity before. Researches paid their attention to single aspects of organization activity where the aspects allowed to increase economic efficiency. However, the objective complication of conditions of enterprises’ activities caused the necessity of scientific research of adequate models of functioning and development of organizations, which currently cannot be provided by traditional management concepts. Thus, theoretical and practical prerequisites arise for a separate scientific set of researches within the science of management such as the theory of an organization. The article describes the main classified approaches to the models of an organization. The paper researches the challenges in present management, and those ones, which have caused the crisis in modern management. It is singled out the following actual aspects of modern organizational processes as the all-round use of modern information and computer systems, the development of integration and in cooperation in management, the appearance of new management technologies, the use of new assessment criteria for organization activity, striving for organizational shifts and innovations. Due to the generalization of the study results, the authors single out such key aspects in the development of the science of management, as the crisis of traditional management influences upon practical activity of modern organizations; the achievements of traditional management schools are becoming necessary, but not determinant factors of organization

  2. Preventing Stress in Organizations How to Develop Positive Managers

    CERN Document Server

    Donaldson-Feilder, Emma; Yarker, Joanna

    2011-01-01

    Preventing Stress in Organizations:How to Develop Positive Managersoffers an innovative, evidence-based approach to help managers prevent and reduce workplace stress in their staff.Provides information on the critical skills managers must develop in order to prevent stress in their staff, and the key ongoing behaviours that promote a healthy work environmentShows practitioners in occupational psychology, HR, Health and Safety and related professions how positive management can be integrated into an organization???s existing practices and processesServes as an essential guide for managers thems

  3. Familial ethnic socialization, gender role attitudes, and ethnic identity development in Mexican-origin early adolescents.

    Science.gov (United States)

    Sanchez, Delida; Whittaker, Tiffany A; Hamilton, Emma; Arango, Sarah

    2017-07-01

    This study examined the relations between familial ethnic socialization and ethnic identity development in 438 Mexican-origin (n = 242 boys and n = 196 girls) preadolescents. In addition, machismo and marianismo gender role attitudes were examined as potential mediators in this link. Confirmatory factor analyses (CFA) of the Familial Ethnic Socialization Scale (FES), Machismo Measure (MM), Marianismo Beliefs Scale (MBS), and the Ethnic Identity Brief Scale (EISB) were conducted to test the factor structure with a preadolescent Mexican-origin sample. Separate path analyses of analytic models were then performed on boys and girls. Results of the CFAs for survey measures revealed that for the FES, a 1-factor version indicated acceptable fit; for the MM, the original 2-factor structure indicated acceptable model fit; for the MBS, a revised 3-factor version indicated acceptable model fit; and, for the EISB, the affirmation and resolution dimensions showed acceptable fit. Among boys, FES was significantly and positively linked to caballerismo, and EISB affirmation and resolution; furthermore, the links between FES and EISB affirmation and resolution were indirectly connected by caballerismo. In addition, traditional machismo was negatively linked to EISB affirmation, and caballerismo was positively linked to EISB affirmation and resolution. Among girls, FES was significantly and positively related to the MBS-virtuous/chaste pillar, and EISB affirmation and resolution. The MBS-subordinate to others pillar was negatively linked to EISB affirmation. This study underscores the importance of FES and positive gender role attitudes in the link to ethnic identity development among Mexican-origin preadolescents. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  4. Origine et developpement des industries de la langue (Origin and Development of Language Utilities). Publication K-8.

    Science.gov (United States)

    L'Homme, Marie-Claude

    The evolution of "language utilities," a concept confined largely to the francophone world and relating to the uses of language in computer science and the use of computer science for languages, is chronicled. The language utilities are of three types: (1) tools for language development, primarily dictionary databases and related tools;…

  5. Intergenerational continuity and discontinuity in Mexican-origin youths' participation in organized activities: insights from mixed-methods.

    Science.gov (United States)

    Simpkins, Sandra D; Vest, Andrea E; Price, Chara D

    2011-12-01

    Motivation theories suggest that parents are an integral support for adolescents' participation in organized activities. Despite the importance of parents, the field knows very little about how parents' own experiences in activities influence the participation of their adolescent children. The goals of this study were to examine (a) the patterns of intergenerational continuity and discontinuity in parents' activity participation during adolescence and their adolescents' activity participation, and (b) the processes underlying each of these patterns within Mexican-origin families. Qualitative and quantitative data were collected through three in-depth interviews conducted with 31 seventh-grade adolescents and their parents at three time points over a year. The quantitative data suggested there was modest intergenerational continuity in activity participation. There were three distinct patterns: nine families were continuous participants, seven families were continuous nonparticipants, and 15 families were discontinuous, where the parent did not participate but the youth did participate in activities. The continuous participant families included families in which parents valued how organized activities contributed to their own lives and actively encouraged their adolescents' participation. The continuous nonparticipant families reported less knowledge and experience with activities along with numerous barriers to participation. There were three central reasons for the change in the discontinuous families. For a third of these families, parents felt strongly about providing a different childhood for their adolescents than what they experienced. The intergenerational discontinuity in participation was also likely to be sparked by someone else in the family or an external influence (i.e., friends, schools).

  6. Molecular Identification of the Carrier of the D-Anomaly in Insoluble Organic Matter of Orgueil Meteorite: Revising the Origin of the IOM?

    Science.gov (United States)

    Remusat, L.; Robert, F.; Meibom, A.; Mostefaoui, S.; Delpoux, O.; Binet, L.; Gourier, D.; Derenne, S.

    2008-03-01

    By combining NanoSIMS measurements and pulsed EPR data, we have identified the organic radicals as the carrier of the D-isotopic anomaly in the insoluble organic matter of Orgueil chondrite. This is consistent with a solar origin of the D-signature.

  7. Helping organizations help others: organization development as a facilitator of social change.

    Science.gov (United States)

    Boyd, Neil M

    2011-01-01

    This article explores organization development (OD) interventions and their likelihood of increasing social change outcomes in public agencies. The central argument of this work is that public and nonprofit organizations can deliver better social outcomes by systematically engaging in OD interventions. An in-depth survey was conducted in 3 agencies of the Commonwealth of Pennsylvania at the end of the gubernatorial administration of Tom Ridge (1995-2002). During his administration, Governor Ridge led the agencies of Pennsylvania government through a large-scale change effort to improve the efficiency and effectiveness of service delivery to the citizens of the Commonwealth of Pennsylvania. The change effort was a remarkable event for the Commonwealth because no other governor in the history of the state had attempted to conceptualize and deliver a comprehensive large-scale change management initiative. The successes and setbacks served as a fertile context to shed light on the following research question: Do OD interventions increase the likelihood that public organizations will deliver better social outcomes? This question is important in that public organizations may need to engage in organization development activities to improve their internal operations, which in turn may help them provide exemplary social outcomes to those whom they serve. In short, organization development interventions might allow public organizations to help themselves to help others.

  8. Role of nanotechnology in development of artificial organs.

    Science.gov (United States)

    Teoh, G Z; Klanrit, P; Kasimatis, M; Seifalian, A M

    2015-02-01

    Improvements in our understanding of the interactions between implants and cells have directed attention towards nanoscale technologies. To date, nanotechnology has played a helping hand in the development of synthetic artificial organs and regenerative medicine. This includes the production of smart nanocomposite materials; fluorescent nanoparticles like Quantum Dots (QD) and magnetic nano particles (MNP) for stem cell tracking; and carbon nanotubes (CNT) and graphene for enhancement of material properties. The scope of this paper includes the role of nanoparticles in the development of nanomaterials; the chemical surface modifications possible to improve implant function and an overview of the performance of nano-engineered organs thus far. This includes implants developed for aesthetic purposes like nasal and auricular scaffolds, plastic and reconstructive surgical constructs (i.e. dermal grafts), hollow organs for cardiothoracic applications; and last but not least, orthopedic implants. The five-year outlook for nano-enhanced artificial organs is also discussed, highlighting the key research and development areas, available funds and the hurdles we face in accomplishing progression from prototypes on the laboratory bench to off-the-shelf products for the consumer market. Ultimately, this review aims to delineate the advantages of incorporating nanotechnology, as an individual entity or as a part of a construct for the development of tissue engineering scaffolds and/or artificial organs, and unravel the mechanisms of tissue cell-biomaterial interactions at the nanoscale, allowing for better progress in the development and optimization of unique nanoscale surface features for a wide range of applications.

  9. Origin of pluripotent germ cell tumours: the role of microenvironment during embryonic development

    DEFF Research Database (Denmark)

    Kristensen, David Møbjerg; Sonne, Si Brask; Ottesen, Anne Marie

    2008-01-01

    into virtually any type of tissue and form teratomas (non-seminomas). CIS cells display a close phenotypic similarity to fetal germ cells (primordial germ cells or gonocytes) suggesting an origin due to a developmental delay or arrest of differentiation of early germ cells. The pluripotency of these neoplasms...... in several tissue specific stem cells, such as TFAP2C (AP-2gamma) or KIT. CIS and seminomas highly express a number of pre-meiotic germ cell specific genes, which are down-regulated during development to non-seminomas, while the expression of other embryonic markers, such as SOX2, is up...

  10. Quantitative regularities of development of endogenous infection in irradiated organism

    International Nuclear Information System (INIS)

    Mal'tsev, V.N.

    1979-01-01

    A statistical analysis of data from the literature and the author's own experimental results are reviewed to show the functional relationships between the radiation dose and the development of endogenous infection in irradiated organisms. A direct linear dependence was found between the dose of radiation and the severity of endogenous infection at doses causing death from the ''bone marrow'' syndrome in acute radiation sickness. In case of death from the ''intestinal'' syndrome, an inverse linear dependence can be observed between the radiation dose and the culture yield of microbes from internal organs. In this case, the pathological effect on the organism is due to bacterial endotoxins formed during the disintegration of microbial cells in the organism. Endogenous infection and endotoxinaemia essentially aggravate the progress of acute radiation disease. The importance of endogenous infection for the death of the organism is minimized in irradiation at doses causing death ''under the ray''. (author)

  11. Social Constructionism in the Context of Organization Development

    Directory of Open Access Journals (Sweden)

    Celiane Camargo-Borges

    2013-05-01

    Full Text Available The world faces rapid changes that call for new epistemologies and methodologies that can generate innovative forms of “being” and “doing” within organizations. This article investigates conceptual and practical resources from the social constructionist perspective that can be useful in realizing the transformation of organizations. Initially, a global context of the world in change is described, explaining the consequences for organizations; then social constructionism is introduced as a postmodern epistemology and offered as a potential approach to the organizational development field in supporting research and intervention. Some perspectives for action and knowledge production are offered in the context of an organization. Finally, some resources with examples will be articulated; these new frameworks for action can be effective for organizations coping in times of change.

  12. Adopting of Agile methods in Software Development Organizations: Systematic Mapping

    Directory of Open Access Journals (Sweden)

    Samia Abdalhamid

    2017-11-01

    Full Text Available Adoption of agile methods in the software development organization is considered as a powerful solution to deal with the quickly changing and regularly developing business environment and fully-educated customers with constantly rising expectation, such as shorter time periods and an extraordinary level of response and service. This study investigates the adoption of agile approaches in software development organizations by using systematic mapping. Six research questions are identified, and to answer these questions a number of research papers have been reviewed in electronic databases. Finally, 25 research papers are examined and answers to all research questions are provided.

  13. Advanced organic analysis and analytical methods development: FY 1995 progress report. Waste Tank Organic Safety Program

    International Nuclear Information System (INIS)

    Wahl, K.L.; Campbell, J.A.; Clauss, S.A.

    1995-09-01

    This report describes the work performed during FY 1995 by Pacific Northwest Laboratory in developing and optimizing analysis techniques for identifying organics present in Hanford waste tanks. The main focus was to provide a means for rapidly obtaining the most useful information concerning the organics present in tank waste, with minimal sample handling and with minimal waste generation. One major focus has been to optimize analytical methods for organic speciation. Select methods, such as atmospheric pressure chemical ionization mass spectrometry and matrix-assisted laser desorption/ionization mass spectrometry, were developed to increase the speciation capabilities, while minimizing sample handling. A capillary electrophoresis method was developed to improve separation capabilities while minimizing additional waste generation. In addition, considerable emphasis has been placed on developing a rapid screening tool, based on Raman and infrared spectroscopy, for determining organic functional group content when complete organic speciation is not required. This capability would allow for a cost-effective means to screen the waste tanks to identify tanks that require more specialized and complete organic speciation to determine tank safety

  14. Development of photocatalysts for selective and efficient organic transformations.

    Science.gov (United States)

    Munir, Shamsa; Dionysiou, Dionysios D; Khan, Sher Bahadar; Shah, Syed Mujtaba; Adhikari, Bimalendu; Shah, Afzal

    2015-07-01

    One of the main goals of organic chemists is to find easy, environmentally friendly, and cost effective methods for the synthesis of industrially important compounds. Photocatalysts have brought revolution in this regard as they make use of unlimited source of energy (the solar light) to carry out the synthesis of organic compounds having otherwise complex synthetic procedures. However, selectivity of the products has been a major issue since the beginning of photocatalysis. The present article encompasses state of the art accomplishments in harvesting light energy for selective organic transformations using photocatalysts. Several approaches for the development of photocatalysts for selective organic conversions have been critically discussed with the objective of developing efficient, selective, environmental friendly and high yield photocatalytic methodologies. Copyright © 2015 Elsevier B.V. All rights reserved.

  15. Potential of electric discharge plasma methods in abatement of volatile organic compounds originating from the food industry.

    Science.gov (United States)

    Preis, S; Klauson, D; Gregor, A

    2013-01-15

    Increased volatile organic compounds emissions and commensurate tightening of applicable legislation mean that the development and application of effective, cost-efficient abatement methods are areas of growing concern. This paper reviews the last two decades' publications on organic vapour emissions from food processing, their sources, impacts and treatment methods. An overview of the latest developments in conventional air treatment methods is presented, followed by the main focus of the paper, non-thermal plasma technology. The results of the review suggest that non-thermal plasma technology, in its pulsed corona discharge configuration, is an emerging treatment method with potential for low-cost, effective abatement of a wide spectrum of organic air pollutants. It is found that the combination of plasma treatment with catalysis is a development trend that demonstrates considerable potential. The as yet relatively small number of plasma treatment applications is considered to be due to the novelty of pulsed electric discharge techniques and a lack of reliable pulse generators and reactors. Other issues acting as barriers to widespread adoption of the technique include the possible formation of stable oxidation by-products, residual ozone and nitrogen oxides, and sensitivity towards air humidity. Copyright © 2012 Elsevier Ltd. All rights reserved.

  16. Information Visualization for Agile Development in Large‐Scale Organizations

    OpenAIRE

    Manzoor, Numan; Shahzad, Umar

    2012-01-01

    Context: Agile/lean development has been successful situations where small teams collaborate over long periods of time with project stakeholders. Unclear is how such teams plan and coordinate their work in such situations where inter-dependencies with other projects exist. In large organizations, scattered teams and complex team structure makes it difficult for every stakeholder to have a clear understanding of project information. These factors make it difficult for large‐scale organizations...

  17. TRENDS IN THE DEVELOPMENT OF ORGANIC FARMING IN BULGARIA

    Directory of Open Access Journals (Sweden)

    Valentina AGAPIEVA

    2015-06-01

    Full Text Available The purpose of this article is to follow trends in the development of organic farming in Bulgaria, and to identify the factors’ strength and direction of their impact on organic production of agricultural products. The study covers the period from 2003 to 2013 and is based on information from official statistics of the Ministry of Agriculture and Food, and the author's own research. There are distinct rates of increase in both areas and organic agricultural production in Bulgaria. While in 2003 the areas under organic management are 8,364 ha by 2013 they numbered 56, 287 ha. Bulgaria has a high potential for production and export of organic agricultural products fresh and processed, but significantly lags behind other European countries. However, there is increasing momentum in organic farming, driven by a group of economic, market, social and legislative initiatives. The main reason for this growth is consumer demand of organic products in Bulgaria. In general, the motivations of Bulgarian consumers of organic products are related to the benefits for health and the environment, to the improvement of food quality and to the support of local small farmers, communities and markets.

  18. Atmospheric water-soluble organic nitrogen (WSON) in the eastern Mediterranean: origin and ramifications regarding marine productivity

    Science.gov (United States)

    Nehir, Münevver; Koçak, Mustafa

    2018-03-01

    Aerosol and rain sampling in two size fractions was carried out at a rural site located on the coast of the eastern Mediterranean, Erdemli, Turkey (36°33'54'' N, 34°15'18'' E). A total of 674 aerosol samples in two size fractions (337 coarse, 337 fine) and 23 rain samples were collected between March 2014 and April 2015. Samples were analyzed for NO3-, NH4+ and ancillary water-soluble ions using ion chromatography and water-soluble total nitrogen (WSTN) by applying a high-temperature combustion method. The mean aerosol water-soluble organic nitrogen (WSON) was 23.8 ± 16.3 nmol N m-3, reaching a maximum of 79 nmol N m-3, with about 66 % being associated with coarse particles. The volume weighted mean (VWM) concentration of WSON in rain was 21.5 µmol N L-1. The WSON contributed 37 and 29 % to the WSTN in aerosol and rainwater, respectively. Aerosol WSON concentrations exhibited large temporal variation, mainly due to meteorology and the origin of air mass flow. The highest mean aerosol WSON concentration was observed in the summer and was attributed to the absence of rain and resuspension of cultivated soil in the region. The mean concentration of WSON during dust events (38.2 ± 17.5 nmol N m-3) was 1.3 times higher than that of non-dust events (29.4 ± 13.9 nmol N m-3). Source apportionment analysis demonstrated that WSON was originated from agricultural activities (43 %), secondary aerosol (20 %), nitrate (22 %), crustal material (10 %) and sea salt (5 %). The dry and wet depositions of WSON were equivalent and amounted to 36 % of the total atmospheric WSTN flux.

  19. Third sector organizations in rural development: a transaction cost perspective

    Directory of Open Access Journals (Sweden)

    V. VALENTINOV

    2008-12-01

    Full Text Available In many parts of the world, rural development is supported by third sector organizations, such as nongovernmental organizations, farmer associations, and cooperatives. This essay develops a transaction cost explanation of these organizations’ role in rural areas. Since the traditional transaction cost theory is concerned with the choice of governance mechanisms within the for-profit sector, this essay adopts an alternative conceptualization of the notion of transaction cost by building on the theory of the division of labor. This theory regards transaction cost as a constraint on the division of labor causing the replacement of exchange with self-sufficiency. The proposed transaction cost explanation of rural third sector organizations consists of two arguments: 1 third sector organizations embody partial reliance on self-sufficiency; and 2 rural areas exhibit rurality-specific transaction cost acting as a constraint on the division of labor and thus creating a niche for third sector organizations. The essay concludes with suggesting a research program on developing an economic theory of the rural third sector.;

  20. Tissue engineered vascular grafts: Origins, development, and current strategies for clinical application.

    Science.gov (United States)

    Benrashid, Ehsan; McCoy, Christopher C; Youngwirth, Linda M; Kim, Jina; Manson, Roberto J; Otto, James C; Lawson, Jeffrey H

    2016-04-15

    Since the development of a dependable and durable synthetic non-autogenous vascular conduit in the mid-twentieth century, the field of vascular surgery has experienced tremendous growth. Concomitant with this growth, development in the field of bioengineering and the development of different tissue engineering techniques have expanded the armamentarium of the surgeon for treating a variety of complex cardiovascular diseases. The recent development of completely tissue engineered vascular conduits that can be implanted for clinical application is a particularly exciting development in this field. With the rapid advances in the field of tissue engineering, the great hope of the surgeon remains that this conduit will function like a true blood vessel with an intact endothelial layer, with the ability to respond to endogenous vasoactive compounds. Eventually, these engineered tissues may have the potential to supplant older organic but not truly biologic technologies, which are used currently. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Development of large scale fusion plasma simulation and storage grid on JAERI Origin3800 system

    International Nuclear Information System (INIS)

    Idomura, Yasuhiro; Wang, Xin

    2003-01-01

    Under the Numerical EXperiment of Tokamak (NEXT) research project, various fluid, particle, and hybrid codes have been developed. These codes require a computational environment which consists of high performance processors, high speed storage system, and high speed parallelized visualization system. In this paper, the performance of the JAERI Origin3800 system is examined from a point of view of these requests. In the performance tests, it is shown that the representative particle and fluid codes operate with 15 - 40% of processing efficiency up to 512 processors. A storage area network (SAN) provides high speed parallel data transfer. A parallel visualization system enables order to magnitude faster visualization of a large scale simulation data compared with the previous graphic workstations. Accordingly, an extremely advanced simulation environment is realized on the JAERI Origin3800 system. Recently, development of a storage grid is underway in order to improve a computational environment of remote users. The storage grid is constructed by a combination of SAN and a wavelength division multiplexer (WDM). The preliminary tests show that compared with the existing data transfer methods, it enables dramatically high speed data transfer ∼100 Gbps over a wide area network. (author)

  2. Application of Bayesian belief net in modelling the origin and effects of terrigenous dissolved organic matter in a boreal aquatic ecosystem

    Science.gov (United States)

    Rahikainen, Mika; Hoikkala, Laura; Soinne, Helena

    2013-04-01

    Bayesian belief nets (BBN) are capable of developing holistic understanding of the origin, transportation, and effects of dissolved organic matter (DOM) in ecosystems. The role of riverine DOM, transporting carbon and macronutrients N and P into lakes and coastal areas, has been largely neglected in research about processes influencing aquatic ecosystem functions although dissolved organic matter provides a significant nutrient source for primary producers in aquatic environments. This neglect has also contributed to the environmental policies which are focused in the control of inorganic N and P load. It is of great social and economic interest to gain improved knowledge of whether the currently applied policy instruments act in synchrony in mitigating eutrophication caused by N and P versus DOM load. DOM is a complex mixture of compounds that are poorly characterized. DOM export is strongly regulated by land use (urban, forest, agricultural land, peat land), in addition to soil type and soil organic carbon concentration. Furthermore, the composition of DOM varies according to its origin. The fate and effects of DOM loads in the fresh water and coastal environments depend, for example, on their biodegradability. Degradation kinetics again depends on the interactions between composition of the DOM pool and the receiving environment. Impact studies of dissolved organic matter pose a complicated environmental impact assessment challenge for science. There exists strategic uncertainty in the science about the causal dependencies and about the quality of knowledge related to DOM. There is a clear need for systematization in the approach as uncertainty is typically high about many key processes. A cross-sectorial, integrative analysis will aid in focusing on the most relevant issues. A holistic and unambiguous analysis will provide support for policy-decisions and management by indicating which outcome is more probable than another. The task requires coupling complex

  3. Sustainable Organic Farming For Environmental Health A Social Development Model

    Directory of Open Access Journals (Sweden)

    Ijun Rijwan Susanto

    2015-05-01

    consider the loss that may be experienced by others as the principles for profit has become very prominent. As a result the development of organic agriculture simply stuck into a commercial activity which would be a criticism of the founders One of the factors that led to the involvement of the government regulated organic farming is because of the bickering about what is called organic agricultural products and because many nonorganic products sold as organic products Organic farmers have difficulty in finding locally based seed for organic farming certification of organic farming has changed it is not just the assurance processes into a tradable commodity 3 The Benefits of Organic Farming in Support for Environmental Health organic farming gives a positive impact on public health because it does not cause environmental pollution water air soil by the residues of chemical fertilizers and synthetic chemical pesticides. Besides organic farming also healthy communities through the provision of agricultural products that are free of pesticides and chemical fertilizer residues 4 The Social Development Model of Sustainable Organic Farming Sustainable agriculture organic farming seeks acre balance of three long-term goals namely a Social-cultural to create quality of life to satisfy personal and community needs for health food safety and happines b Environment to Enhance utilization of soil water air and other resourches limited c Economics to be profitable market forces. These objectives can be achieved if supported by organizational-oriented good governance principles of sustainable agriculture. Sustainable agriculture is the implementation of the principles of sustainable development. Sustainable development will be achieved if conducted prior social development within the broad scope of stakeholders 5 The Policy Recomendation for Organic Farming a National Strategic Agenda The Program Go Organic must be forwarded with the 2010 program Go Organic 2020 where the formulation of

  4. Original and Derived Judgment

    DEFF Research Database (Denmark)

    Foss, Kirsten; Foss, Nicolai Juul; Klein, Peter G.

    and own assets. The entrepreneur's role, then, is to arrange or organize the human and capital assets under his control. We extend this Knightian concept of the firm by developing a theory of delegation under Knightian uncertainty. What we call original judgment belongs exclusively to owners, but owners...

  5. Report of evaluation of organization. Japan Nuclear Cycle Development Institute

    International Nuclear Information System (INIS)

    2004-08-01

    Various activities of JNC (Japan Nuclear Cycle Development Institute) from December in 2003 to July in 2004 are evaluated on management, practice and progressing of development of research by the committee on organization evaluation. The report includes abstract, purpose of evaluation, evaluation items, deliberation process, total results of evaluation, development of projects, the spread of results, international cooperation, management system, effort to safety, responsibility of explanation, live together with community and other suggestions. Main projects consists of practice of FBR, development of uranium enrichment, nuclear fuel reprocessing and MOX fuel processing technology, reopening of MONJU, development of high-level radioactive waste and environmental protection policy. (S.Y.)

  6. Supporting Usability Engineering in Small Software Development Organizations

    DEFF Research Database (Denmark)

    Bornoe, Nis; Stage, Jan

    2013-01-01

    Despite an interest and use of different usability engineering methods small software development organizations find it challenging to implement usability engineering into the software development process. We present the results from a study about usability engineering in practice. Through a series...... of semistructured interviews we want to get an understanding of how usability is implemented into the organizations and how it’s practiced in reality. We found that the developers found it problematic to combine agile software development methods with classic usability engineering methods. A lack of solid usability...... engineering expertise and not least experience seems to be a main obstacle for a successful implementation of usability engineering into current software development practices. They are requesting methods and procedures that fit better with their current practices and strategies to implement usability...

  7. The Biblicism of the Korean Protestant churches: Its origin and early development

    Directory of Open Access Journals (Sweden)

    Jae-Buhm Hwang

    2016-09-01

    Full Text Available The purpose of this article is to clarify the origin and early stages of the Biblicism of the Korean Protestant churches in general, and of the Presbyterian Church of Korea (PCK in particular. The Biblicism is very important for Korean Protestant churches, because it is believed to be a main cause of their unusual growth on the one hand, and on the other hand, of their Fundamentalism and many schisms in the post-liberation era. The article, in the beginning part, investigates the four crucial elements of Korean Biblicism and then examines how the four elements worked together to form a resilient Biblicism whose two distinctive theological forms were practical on the one hand, and dogmatic (fundamentalist, on the other. Among the four basic Biblicist elements, the first was the firm Biblicist theology of the early North American missionaries in Korea who tried to follow and flower their original, puritanical and Old Princeton theology in Korea. The second was Korean Protestants’ original, Neo-Confucian biblicism, which facilitated them to readily accept the missionaries’ Biblicist teachings of the Bible. The third element was the so-called Nevius [Mission] Methods, which emphasised simplistic Biblicist Bible studies, and offered both opportunities of learning and ways to become meaningful leaders in their communities. The fourth and last element was the Biblicist creed of PCK, which became the fundamentalist weapon against its modernist or liberalist wing. To sum up, Korean Biblicism has been the result of those four Biblicist elements working together. The Korean Biblicism was developed into two more or less different positions; the one being practical, exemplified by Rev. Samuel A. Moffett; and the other, dogmatic and fundamentalist, represented by Rev. Dr W.D. Reynolds.

  8. The Biblicism of the Korean Protestant churches: Its origin and early development

    Directory of Open Access Journals (Sweden)

    Jae-Buhm Hwang

    2016-04-01

    Full Text Available The purpose of this article is to clarify the origin and early stages of the Biblicism of the Korean Protestant churches in general, and of the Presbyterian Church of Korea (PCK in particular. The Biblicism is very important for Korean Protestant churches, because it is believed to be a main cause of their unusual growth on the one hand, and on the other hand, of their Fundamentalism and many schisms in the post-liberation era. The article, in the beginning part, investigates the four crucial elements of Korean Biblicism and then examines how the four elements worked together to form a resilient Biblicism whose two distinctive theological forms were practical on the one hand, and dogmatic (fundamentalist, on the other. Among the four basic Biblicist elements, the first was the firm Biblicist theology of the early North American missionaries in Korea who tried to follow and flower their original, puritanical and Old Princeton theology in Korea. The second was Korean Protestants’ original, Neo-Confucian biblicism, which facilitated them to readily accept the missionaries’ Biblicist teachings of the Bible. The third element was the so-called Nevius [Mission] Methods, which emphasised simplistic Biblicist Bible studies, and offered both opportunities of learning and ways to become meaningful leaders in their communities. The fourth and last element was the Biblicist creed of PCK, which became the fundamentalist weapon against its modernist or liberalist wing. To sum up, Korean Biblicism has been the result of those four Biblicist elements working together. The Korean Biblicism was developed into two more or less different positions; the one being practical, exemplified by Rev. Samuel A. Moffett; and the other, dogmatic and fundamentalist, represented by Rev. Dr W.D. Reynolds.

  9. Uranium exploration, non-governmental organizations, and local communities. The origin, anatomy, and consequences of a new challenge in Finland

    Directory of Open Access Journals (Sweden)

    Eerola, Toni

    2008-06-01

    Full Text Available The advent of global warming has returned nuclear power to the agenda. Many countries, including Finland, have decided to construct more nuclear power plants. They will need uranium, and its price is rising in the international market. A new uranium exploration boom is going on. Finland is politically and economically stable, with good infrastructure and basic geodata, attracting foreign companies to explore the promising uranium showings of the country. However, this has triggered an extensive anti-uranium campaign in northern, eastern, and southern, but not in central Finland, which is related to anti-nuclear movement, green and leftist parties, and environmental non-governmental organizations (NGOs. The resistance, created mainly by lack of public awareness of geology and mining, surprised mining companies, the geological community, and the Ministry of Trade and Industry, who found themselves in a completely new situation. Here we will examine the origin, anatomy, and consequences of this challenge and how to deal with it. The picture presented herewithin is based on author’s active participation in uranium exploration in Finland, discussions with other geologists and activists, following the issue in newspapers, web-pages, reviews, and participating in NGO meetings.

  10. Origin of the Strain Sensitivity for an Organic Heptazole Thin-Film and Its Strain Gauge Application

    Science.gov (United States)

    Bae, Heesun; Jeon, Pyo Jin; Park, Ji Hoon; Lee, Kimoon

    2018-04-01

    The authors report on the origin of the strain sensitivity for an organic C26H16N2 (heptazole) thinfilm and its application for the detection of tensile strain. From the electrical characterization on the thin-film transistor adopting a heptazole channel, heptazole film exhibits p-channel conduction with a relatively low value of field-effect mobility (0.05 cm2/Vs), suggesting a hopping conduction behavior via hole carriers. By analyzing the strain and temperature dependences of the electrical conductivity, we reveal that the electrical conduction for a heptazole thin-film is dominated by the variable range hopping process with quite a large energy separation (224.9 meV) between the localized states under a relatively long attenuation length (10.46 Å). This indicates that a change in the inter-grain spacing that is much larger than the attenuation length is responsible for the reversible modification of electrical conductivity depending on strain for the heptazole film. By utilizing our heptazole thin-film both as a strain sensitive passive resistor and an active semiconducting channel layer, we can achieve a strain gauge device exhibiting reversible endurance for tensile strains up to 2.12%. Consequently, this study advances the understanding of the fundamental strain sensing mechanism in a heptazole thin-film toward finding a promise material with a strain gauge for applications as potential flexible devices and/or wearable electronics.

  11. Origin of polycyclic aromatic hydrocarbons and other organic pollutants in the air particles of subway stations in Barcelona.

    Science.gov (United States)

    van Drooge, Barend L; Prats, Raimon M; Reche, Cristina; Minguillón, MariCruz; Querol, Xavier; Grimalt, Joan O; Moreno, Teresa

    2018-06-09

    Underground subways transport large numbers of citizens in big cities, which must breathe air with limited ventilation. These atmospheric conditions may enhance the concentration of air pollutants from both outdoor and indoor air. The influence of ventilation conditions and maintenance activities on the concentrations of air pollutants have been studied. Particulate matter with aerodynamic diameter smaller than 2.5 μm (PM 2.5 ) in indoor air was sampled in ten platforms of nine subway stations of the metropolitan area of Barcelona in 2015 and 2016. These particles were analyzed for polycyclic aromatic hydrocarbons (PAH) and organic tracer compounds. The concentrations of PAH were in the range of the street air levels with higher PAH values in the colder period. No influence of nighttime maintenance activities was observed on the platform air quality during daytime. Source apportionment analysis using the concentrations of hopanes, nicotine and levoglucosan as molecular tracer compounds showed that 75% of the detected PAH at the platforms have an outdoor PM origin. The modern subway stations, with advanced ventilation and platform screen doors that separate the subway system from the platform, showed lowest PAH and PM concentrations. Copyright © 2018. Published by Elsevier B.V.

  12. Investigation of normal organ development with fetal MRI

    International Nuclear Information System (INIS)

    Prayer, Daniela; Brugger, Peter C.

    2007-01-01

    The understanding of the presentation of normal organ development on fetal MRI forms the basis for recognition of pathological states. During the second and third trimesters, maturational processes include changes in size, shape and signal intensities of organs. Visualization of these developmental processes requires tailored MR protocols. Further prerequisites for recognition of normal maturational states are unequivocal intrauterine orientation with respect to left and right body halves, fetal proportions, and knowledge about the MR presentation of extrafetal/intrauterine organs. Emphasis is laid on the demonstration of normal MR appearance of organs that are frequently involved in malformation syndromes. In addition, examples of time-dependent contrast enhancement of intrauterine structures are given. (orig.)

  13. Investigation of normal organ development with fetal MRI

    Energy Technology Data Exchange (ETDEWEB)

    Prayer, Daniela [Medical University of Vienna, Department of Radiology, Vienna (Austria); Brugger, Peter C. [Medical University of Vienna, Center of Anatomy and Cell Biology, Integrative Morphology Group, Vienna (Austria)

    2007-10-15

    The understanding of the presentation of normal organ development on fetal MRI forms the basis for recognition of pathological states. During the second and third trimesters, maturational processes include changes in size, shape and signal intensities of organs. Visualization of these developmental processes requires tailored MR protocols. Further prerequisites for recognition of normal maturational states are unequivocal intrauterine orientation with respect to left and right body halves, fetal proportions, and knowledge about the MR presentation of extrafetal/intrauterine organs. Emphasis is laid on the demonstration of normal MR appearance of organs that are frequently involved in malformation syndromes. In addition, examples of time-dependent contrast enhancement of intrauterine structures are given. (orig.)

  14. Geographical Basis for Development of Organic Olive Grow in Croatia

    Directory of Open Access Journals (Sweden)

    Anica Čuka

    2002-01-01

    Full Text Available Conventional agriculture is among the biggest polluters of the environment. Overuse of synthetic pesticides, herbicides and mineral fertilisers have caused soil exhaustion, erosion, unbalance in the ecosystem, and their harmful effect on human health has been proven. This is why the author tried to point to the importance of development of organic agriculture, and olive growing as a traditional agricultural sector in coastal Croatia.The main intention is to show the basic geographical aspects of coastal Croatia and to explain the ways it can influence the development of organic olive farming. It is specially emphasized that organically produced food must be incorporated in Croatian tourist offer. It will stimulate a bigger interest for Croatia as an attractive tourist destination in the world tourist market and will simplify the sale of organically produced food. Development of organic olive farming will also contribute to the revitalisation of small villages where a strong presence of negative processes, such as deagrarisation, deruralisation and demographic regression is evident.

  15. Development of a culture of sustainability in health care organizations.

    Science.gov (United States)

    Ramirez, Bernardo; West, Daniel J; Costell, Michael M

    2013-01-01

    This paper aims to examine the concept of sustainability in health care organizations and the key managerial competencies and change management strategies needed to implant a culture of sustainability. Competencies and management development strategies needed to engrain this corporate culture of sustainability are analyzed in this document. This paper draws on the experience of the authors as health care executives and educators developing managerial competencies with interdisciplinary and international groups of executives in the last 25 years, using direct observation, interviews, discussions and bibliographic evidence. With a holistic framework for sustainability, health care managers can implement strategies for multidisciplinary teams to respond to the constant change, fine-tune operations and successfully manage quality of care. Managers can mentor students and provide in-service learning experiences that integrate knowledge, skills, and abilities. Further empirical research needs to be conducted on these interrelated innovative topics. Health care organizations around the world are under stakeholders' pressure to provide high quality, cost-effective, accessible and sustainable services. Professional organizations and health care providers can collaborate with university graduate health management education programs to prepare competent managers in all the dimensions of sustainability. The newly designated accountable care organizations represent an opportunity for managers to address the need for sustainability. Sustainability of health care organizations with the holistic approach discussed in this paper is an innovative and practical approach to quality improvement that merits further development.

  16. Cultural-historical and cognitive approaches to understanding the origins of development of written speech

    Directory of Open Access Journals (Sweden)

    L.F. Obukhova

    2014-08-01

    Full Text Available We present an analysis of the emergence and development of written speech, its relationship to the oral speech, connections to the symbolic and modeling activities of preschool children – playing and drawing. While a child's drawing is traditionally interpreted in psychology either as a measure of intellectual development, or as a projective technique, or as a criterion for creative giftedness of the child, in this article, the artistic activity is analyzed as a prerequisite for development of written speech. The article substantiates the hypothesis that the mastery of “picture writing” – the ability to display the verbal content in a schematic picturesque plan – is connected to the success of writing speech at school age. Along with the classical works of L.S. Vygotsky, D.B. Elkonin, A.R. Luria, dedicated to finding the origins of writing, the article presents the current Russian and foreign frameworks of forming the preconditions of writing, based on the concepts of cultural-historical theory (“higher mental functions”, “zone of proximal development”, etc.. In Western psychology, a number of pilot studies used the developmental function of drawing for teaching the written skills to children of 5-7 years old. However, in cognitive psychology, relationship between drawing and writing is most often reduced mainly to the analysis of general motor circuits. Despite the recovery in research on writing and its origins in the last decade, either in domestic or in foreign psychology, the written speech is not a sufficiently studied problem.

  17. The early life origin theory in the development of cardiovascular disease and type 2 diabetes.

    Science.gov (United States)

    Lindblom, Runa; Ververis, Katherine; Tortorella, Stephanie M; Karagiannis, Tom C

    2015-04-01

    Life expectancy has been examined from a variety of perspectives in recent history. Epidemiology is one perspective which examines causes of morbidity and mortality at the population level. Over the past few 100 years there have been dramatic shifts in the major causes of death and expected life length. This change has suffered from inconsistency across time and space with vast inequalities observed between population groups. In current focus is the challenge of rising non-communicable diseases (NCD), such as cardiovascular disease and type 2 diabetes mellitus. In the search to discover methods to combat the rising incidence of these diseases, a number of new theories on the development of morbidity have arisen. A pertinent example is the hypothesis published by David Barker in 1995 which postulates the prenatal and early developmental origin of adult onset disease, and highlights the importance of the maternal environment. This theory has been subject to criticism however it has gradually gained acceptance. In addition, the relatively new field of epigenetics is contributing evidence in support of the theory. This review aims to explore the implication and limitations of the developmental origin hypothesis, via an historical perspective, in order to enhance understanding of the increasing incidence of NCDs, and facilitate an improvement in planning public health policy.

  18. Using inertial measurement units originally developed for biomechanics for modal testing of civil engineering structures

    Science.gov (United States)

    Hester, David; Brownjohn, James; Bocian, Mateusz; Xu, Yan; Quattrone, Antonino

    2018-05-01

    This paper explores the use of wireless Inertial Measurement Units (IMU) originally developed for bio-mechanical research applications for modal testing of civil engineering infrastructure. Due to their biomechanics origin, these devices combine a triaxial accelerometer with gyroscopes and magnetometers for orientation, as well as on board data logging capability and wireless communication for optional data streaming and to coordinate synchronisation with other IMUs in a network. The motivation for application to civil structures is that their capabilities and simple operating procedures make them suitable for modal testing of many types of civil infrastructure of limited dimension including footbridges and floors while also enabling recovering of dynamic forces generated and applied to structures by moving humans. To explore their capabilities in civil applications, the IMUs are evaluated through modal tests on three different structures with increasing challenge of spatial and environmental complexity. These are, a full-scale floor mock-up in a laboratory, a short span road bridge and a seven story office tower. For each case, the results from the IMUs are compared with those from a conventional wired system to identify the limitations. The main conclusion is that the relatively high noise floor and limited communication range will not be a serious limitation in the great majority of typical civil modal test applications where convenient operation is a significant advantage over conventional wired systems.

  19. The origins, early development and status of Bourdieu's concept of 'cultural capital'.

    Science.gov (United States)

    Robbins, Derek

    2005-03-01

    The paper examines the context of the first introduction of the concept of 'cultural capital' in the sociology of education analyses undertaken in the early 1960s and published by Bourdieu in collaboration with Jean-Claude Passeron in 'Les etudiants et leurs etudes' (1964a) and Les Heritiers (1964b). It first considers the cultural contexts within which Bourdieu's thinking about culture originated--both in relation to his social origins and in relation to his intellectual training. It then examines the extent to which Bourdieu's early anthropological research in Algeria was influenced by his knowledge of American acculturation theory. It concludes that Bourdieu sought to use acculturation theory in a distinctive way--one which he articulated more confidently as he explored the relationship between agency and structural explanation in the late 1960s and early 1970s. The specific educational researches which stimulated the articulation of the concept of 'linguistic' or 'cultural' capital belonged to the period in which Bourdieu was only just beginning to refine his post-structuralist philosophy of social scientific explanation. To use these concepts now involves deploying them reflexively in accordance with Bourdieu's later thinking rather than at face value as they were first developed during the period in which he and Passeron were 'apprentice' researchers.

  20. Intentional Design of Student Organizations to Optimize Leadership Development.

    Science.gov (United States)

    Mainella, Felicia C

    2017-09-01

    This chapter addresses how a group's organizational structure can promote or hinder the leadership capacity of its members. The information in this chapter provides insight into structuring student organizations in a way to maximize all members' leadership development. © 2017 Wiley Periodicals, Inc., A Wiley Company.

  1. Development of a Soil Organic Carbon Baseline for Otjozondjupa, Namibia

    NARCIS (Netherlands)

    Nijbroek, R.; Kempen, B.; Mutua, J.; Soderstrom, M.; Piikki, K.; Hengari, S.; Andreas, A.

    2017-01-01

    Land Degradation Neutrality (LDN) has been piloted in 14 countries and will be scaled up to over 120 countries. As a LDN pilot country, Namibia developed sub-national LDN baselines in Otjozondjupa Region. In addition to the three LDN indicators (soil organic carbon, land productivity and land cover

  2. Some Unintended Consequences of "Top Down" Organization Development

    Science.gov (United States)

    White, Bernard J.; Ramsey, V. Jean

    1978-01-01

    An organizational development consultant is expected to perform a thorough and unbiased diagnosis of the organization's functioning. This is an account of a case study of the effect of top management influence on the consultant's awareness and definition of problems. (Author/MLF)

  3. Culturing Reality: How Organic Chemistry Graduate Students Develop into Practitioners

    Science.gov (United States)

    Bhattacharyya, Gautam; Bodner, George M.

    2014-01-01

    Although one of the presumed aims of graduate training programs is to help students develop into practitioners of their chosen fields, very little is known about how this transition occurs. In the course of studying how graduate students learn to solve organic synthesis problems, we were able to identify some of the key factors in the epistemic…

  4. Role of Women Organizations in Community Development: A Case ...

    African Journals Online (AJOL)

    The paper analysed the role of women organizations in the development of rural communities in Orlu Agricultural zone of Imo state. Six communities were purposively selected from three Local Government Areas of the Zone for the study. Semi-structured questionnaire was used to collect data from 120 randomly selected ...

  5. How the challenge of explaining learning influenced the origins and development of John B. Watson's behaviorism.

    Science.gov (United States)

    Rilling, M

    2000-01-01

    Before he invented behaviorism, John B. Watson considered learning one of the most important topics in psychology. Watson conducted excellent empirical research on animal learning. He developed behaviorism in part to promote research and elevate the status of learning in psychology. Watson was much less successful in the adequacy and originality of the mechanisms he proposed to explain learning. By assimilating the method of classical conditioning and adopting Pavlov's theory of stimulus substitution, Watson linked behaviorism with a new method that could compete with both Titchener's method of introspection and Freud's methods of psychoanalysis. Watson's interest in explaining psychopathology led to the discovery of conditioned emotional responses and a behavioristic explanation for the learning of phobic behavior. Watson established learning as a central topic for basic research and application in American psychology.

  6. Developing a new service for organizing social events in Finland

    OpenAIRE

    Mohanty, Titikshya

    2017-01-01

    The purpose of this thesis is to develop a new service concept for people living in Finland by using service design methods. In this busy world, people frequently have no time to organize events on their own. Therefore, service design tools and methodology will be used as foundational pillars for the case company in this thesis in developing solutions for this issue, as well as bringing customer satisfaction from service delivery. This service concept is designed to save time and simplify the...

  7. Cell chirality: its origin and roles in left-right asymmetric development.

    Science.gov (United States)

    Inaki, Mikiko; Liu, Jingyang; Matsuno, Kenji

    2016-12-19

    An item is chiral if it cannot be superimposed on its mirror image. Most biological molecules are chiral. The homochirality of amino acids ensures that proteins are chiral, which is essential for their functions. Chirality also occurs at the whole-cell level, which was first studied mostly in ciliates, single-celled protozoans. Ciliates show chirality in their cortical structures, which is not determined by genetics, but by 'cortical inheritance'. These studies suggested that molecular chirality directs whole-cell chirality. Intriguingly, chirality in cellular structures and functions is also found in metazoans. In Drosophila, intrinsic cell chirality is observed in various left-right (LR) asymmetric tissues, and appears to be responsible for their LR asymmetric morphogenesis. In other invertebrates, such as snails and Caenorhabditis elegans, blastomere chirality is responsible for subsequent LR asymmetric development. Various cultured cells of vertebrates also show intrinsic chirality in their cellular behaviours and intracellular structural dynamics. Thus, cell chirality may be a general property of eukaryotic cells. In Drosophila, cell chirality drives the LR asymmetric development of individual organs, without establishing the LR axis of the whole embryo. Considering that organ-intrinsic LR asymmetry is also reported in vertebrates, this mechanism may contribute to LR asymmetric development across phyla.This article is part of the themed issue 'Provocative questions in left-right asymmetry'. © 2016 The Authors.

  8. Cell chirality: its origin and roles in left–right asymmetric development

    Science.gov (United States)

    Inaki, Mikiko; Liu, Jingyang

    2016-01-01

    An item is chiral if it cannot be superimposed on its mirror image. Most biological molecules are chiral. The homochirality of amino acids ensures that proteins are chiral, which is essential for their functions. Chirality also occurs at the whole-cell level, which was first studied mostly in ciliates, single-celled protozoans. Ciliates show chirality in their cortical structures, which is not determined by genetics, but by ‘cortical inheritance’. These studies suggested that molecular chirality directs whole-cell chirality. Intriguingly, chirality in cellular structures and functions is also found in metazoans. In Drosophila, intrinsic cell chirality is observed in various left–right (LR) asymmetric tissues, and appears to be responsible for their LR asymmetric morphogenesis. In other invertebrates, such as snails and Caenorhabditis elegans, blastomere chirality is responsible for subsequent LR asymmetric development. Various cultured cells of vertebrates also show intrinsic chirality in their cellular behaviours and intracellular structural dynamics. Thus, cell chirality may be a general property of eukaryotic cells. In Drosophila, cell chirality drives the LR asymmetric development of individual organs, without establishing the LR axis of the whole embryo. Considering that organ-intrinsic LR asymmetry is also reported in vertebrates, this mechanism may contribute to LR asymmetric development across phyla. This article is part of the themed issue ‘Provocative questions in left–right asymmetry’. PMID:27821533

  9. Becoming organisms: the organisation of development and the development of organisation.

    Science.gov (United States)

    de la Rosa, Laura Nuño

    2010-01-01

    Despite the radical importance of embryology in the development of organicism, developmental biology remains philosophically underexplored as a theoretical and empirical resource to clarify the nature of organisms. This paper discusses how embryology can help develop the organisational definition of the organism as a differentiated, functionally integrated, and autonomous system. I distinguish two conceptions of development in the organisational tradition that yield two different conceptions of the organism: the life-history view claims that organisms can be considered as such during their whole ontogeny; the constitutive view distinguishes two periods in the life history, a period of generation and a period of self-maintenance of a constitutive organisation. Arguing in favour of the constitutive view, it will be claimed that the organisational criteria for the definition of organism (i.e., differentiation, functional integration, and autonomy) can only be applied to the developmental system when it has entered the period of self-maintenance of a constitutive organisation. Under the light of current research in developmental biology, it is possible to make explicit how organisms come to be as organisms. To this end, I explore key ontogenetic events that help us clarify the core aspects of animal organisation and allow us to identify the developmental stage that marks the ontological transition between an organism in potency and an organism in actuality. The structure of this ontogenetic unfolding parallels the conceptual structure of the very notion of organism; the generation of the being of a particular organism parallels its definition.

  10. The Developmental Origins of Health and Disease and Sustainable Development Goals: mapping the way forward.

    Science.gov (United States)

    Kajee, N; Sobngwi, E; Macnab, A; Daar, A S

    2018-02-01

    In this paper, meant to stimulate debate, we argue that there is considerable benefit in approaching together the implementation of two seemingly separate recent developments. First, on the global development agenda, we have the United Nations General Assembly's 2015 finalized list of 17 Sustainable Development Goals (SDGs). Several of the SDGs are related to health. Second, the field of Developmental Origins of Health and Disease (DOHaD) has garnered enough compelling evidence demonstrating that early exposures in life affect not only future health, but that the effects of that exposure can be transmitted across generations - necessitating that we begin to focus on prevention. We argue that implementing the SDGs and DOHaD together will be beneficial in several ways; and will require attending to multiple, complex and multidisciplinary approaches as we reach the point of translating science to policy to impact. Here, we begin by providing the context for our work and making the case for a mutually reinforcing, synergistic approach to implementing SDGs and DOHaD, particularly in Africa. To do this, we initiate discussion via an early mapping of some of the overlapping considerations between SDGs and DOHaD.

  11. Modern leadership and management methods for development organizations

    Directory of Open Access Journals (Sweden)

    Samosudova Natalia V.

    2017-01-01

    Full Text Available The following article represents an overview of the basic theoretical concepts of leadership and management in the framework of the organization. The main scientific approaches to leadership are described in conjunction with various leadership styles and their correlation with different levels of effectiveness as a result of the organization’s activity. Certain characteristics applicable to leaders and managers are mentioned. Attitude and obligations of a modern construction project manager are discussed, along with the challenges the construction industry represents these days. Ideas about methods of complex analysis for further research and identifying leadership tactics and their impact on the success of the development organization are suggested.

  12. Development of Organ-Specific Donor Risk Indices

    Science.gov (United States)

    Akkina, Sanjeev K.; Asrani, Sumeet K.; Peng, Yi; Stock, Peter; Kim, Ray; Israni, Ajay K.

    2012-01-01

    Due to the shortage of deceased donor organs, transplant centers accept organs from marginal deceased donors, including older donors. Organ-specific donor risk indices have been developed to predict graft survival using various combinations of donor and recipient characteristics. We will review the kidney donor risk index (KDRI) and liver donor risk index (LDRI) and compare and contrast their strengths, limitations, and potential uses. The Kidney Donor Risk Index has a potential role in developing new kidney allocation algorithms. The Liver Donor Risk Index allows for greater appreciation of the importance of donor factors, particularly for hepatitis C-positive recipients; as the donor risk index increases, rates of allograft and patient survival among these recipients decrease disproportionately. Use of livers with high donor risk index is associated with increased hospital costs independent of recipient risk factors, and transplanting livers with high donor risk index into patients with Model for End-Stage Liver Disease scores Donor Risk Index has limited this practice. Significant regional variation in donor quality, as measured by the Liver Donor Risk Index, remains in the United States. We also review other potential indices for liver transplant, including donor-recipient matching and the retransplant donor risk index. While substantial progress has been made in developing donor risk indices to objectively assess donor variables that affect transplant outcomes, continued efforts are warranted to improve these indices to enhance organ allocation policies and optimize allograft survival. PMID:22287036

  13. Development of organ-specific donor risk indices.

    Science.gov (United States)

    Akkina, Sanjeev K; Asrani, Sumeet K; Peng, Yi; Stock, Peter; Kim, W Ray; Israni, Ajay K

    2012-04-01

    Because of the shortage of deceased donor organs, transplant centers accept organs from marginal deceased donors, including older donors. Organ-specific donor risk indices have been developed to predict graft survival with various combinations of donor and recipient characteristics. Here we review the kidney donor risk index (KDRI) and the liver donor risk index (LDRI) and compare and contrast their strengths, limitations, and potential uses. The KDRI has a potential role in developing new kidney allocation algorithms. The LDRI allows a greater appreciation of the importance of donor factors, particularly for hepatitis C virus-positive recipients; as the donor risk index increases, the rates of allograft and patient survival among these recipients decrease disproportionately. The use of livers with high donor risk indices is associated with increased hospital costs that are independent of recipient risk factors, and the transplantation of livers with high donor risk indices into patients with Model for End-Stage Liver Disease scores indices for liver transplantation, including donor-recipient matching and the retransplant donor risk index. Although substantial progress has been made in developing donor risk indices to objectively assess donor variables that affect transplant outcomes, continued efforts are warranted to improve these indices to enhance organ allocation policies and optimize allograft survival. Copyright © 2012 American Association for the Study of Liver Diseases.

  14. Recent developments in organic redox flow batteries: A critical review

    Science.gov (United States)

    Leung, P.; Shah, A. A.; Sanz, L.; Flox, C.; Morante, J. R.; Xu, Q.; Mohamed, M. R.; Ponce de León, C.; Walsh, F. C.

    2017-08-01

    Redox flow batteries (RFBs) have emerged as prime candidates for energy storage on the medium and large scales, particularly at the grid scale. The demand for versatile energy storage continues to increase as more electrical energy is generated from intermittent renewable sources. A major barrier in the way of broad deployment and deep market penetration is the use of expensive metals as the active species in the electrolytes. The use of organic redox couples in aqueous or non-aqueous electrolytes is a promising approach to reducing the overall cost in long-term, since these materials can be low-cost and abundant. The performance of such redox couples can be tuned by modifying their chemical structure. In recent years, significant developments in organic redox flow batteries has taken place, with the introduction of new groups of highly soluble organic molecules, capable of providing a cell voltage and charge capacity comparable to conventional metal-based systems. This review summarises the fundamental developments and characterization of organic redox flow batteries from both the chemistry and materials perspectives. The latest advances, future challenges and opportunities for further development are discussed.

  15. WHAT ARE THE BARRIERS TO THE DEVELOPMENT OF ORGANIC FARMING?

    Directory of Open Access Journals (Sweden)

    Afagh VEISI

    2013-10-01

    Full Text Available The main purpose of this study was to investigate the main barriers to development of organic farming system in Kermanshah Province, Iran. Statistical population in this study consisted of all farmers in Kermanshah province, Iran. Applying stratified random sampling method, 137 farmers were selected as a sample. The main instrument in this study was questionnaire which its validity was confirmed by the panel of experts and its reliability was established by Cronbach's Alpha coefficient. Data was analyzed by SPSSWin16 software. Principal component analysis was used as main statistical technique to analyze the data. The results of factor analysis revealed that 4 factors including “Infrastructural”, “technical-managerial”, “economic-financial” and “educational” explained 42.36 percent of the variance. Results of this study have applications for agriculture development policy- makers for development of organic farming in Iran.

  16. Developing a Security Metrics Scorecard for Healthcare Organizations.

    Science.gov (United States)

    Elrefaey, Heba; Borycki, Elizabeth; Kushniruk, Andrea

    2015-01-01

    In healthcare, information security is a key aspect of protecting a patient's privacy and ensuring systems availability to support patient care. Security managers need to measure the performance of security systems and this can be achieved by using evidence-based metrics. In this paper, we describe the development of an evidence-based security metrics scorecard specific to healthcare organizations. Study participants were asked to comment on the usability and usefulness of a prototype of a security metrics scorecard that was developed based on current research in the area of general security metrics. Study findings revealed that scorecards need to be customized for the healthcare setting in order for the security information to be useful and usable in healthcare organizations. The study findings resulted in the development of a security metrics scorecard that matches the healthcare security experts' information requirements.

  17. Development of the destruction technology for radioactive organic solid wastes

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Won Zin; Park, H.S.; Lee, K.W. [and others

    1999-04-01

    The followings were studied through the project entitled 'Technology development for nuclear fuel cycle waste treatment'. 1. Organic waste decomposition technology development A. Destruction technology for organic wastes using Ag(2)-mediated electrochemical oxidation B. Recovery and regeneration technology for the spent chemicals used in the MEO process 2. Radioactive metal waste recycling technology A. Surface decontamination processes B. Decontamination waste treatment technology 3. Volume reduction technology nuclear fuel cycle (NFC) technology A. Estimation of the amount of radwastes and the optimum volume reduction methodology of domestic NFC B. Pretreatment of spent fuel cladding by electrochemical decontamination C. Hot cell process technology for the treatment of NFC wastes 4. Design and fabrication of the test equipment of volume reduction and reuse of alpha contaminated wastes 5. Evaluation on environmental compatibility of NFC A. Development of evaluation methodology on environmental friendliness of NFC B. Residual activity assessment of recycling wastes. (author). 321 refs., 54 tabs., 183 figs.

  18. Development of the destruction technology for radioactive organic solid wastes

    International Nuclear Information System (INIS)

    Oh, Won Zin; Park, H.S.; Lee, K.W.

    1999-04-01

    The followings were studied through the project entitled 'Technology development for nuclear fuel cycle waste treatment'. 1. Organic waste decomposition technology development A. Destruction technology for organic wastes using Ag(2)-mediated electrochemical oxidation B. Recovery and regeneration technology for the spent chemicals used in the MEO process 2. Radioactive metal waste recycling technology A. Surface decontamination processes B. Decontamination waste treatment technology 3. Volume reduction technology nuclear fuel cycle (NFC) technology A. Estimation of the amount of radwastes and the optimum volume reduction methodology of domestic NFC B. Pretreatment of spent fuel cladding by electrochemical decontamination C. Hot cell process technology for the treatment of NFC wastes 4. Design and fabrication of the test equipment of volume reduction and reuse of alpha contaminated wastes 5. Evaluation on environmental compatibility of NFC A. Development of evaluation methodology on environmental friendliness of NFC B. Residual activity assessment of recycling wastes. (author). 321 refs., 54 tabs., 183 figs

  19. Origin, concentration, availability and fate of dissolved organic carbon in coastal lagoons of the Rio de Janeiro State

    Directory of Open Access Journals (Sweden)

    Albert Luiz Suhett

    Full Text Available The coastal lagoons in the northern Rio de Janeiro State (Brazil present a wide gradient of dissolved organic carbon (DOC and water color, with the highest DOC concentrations reported in the literature for aquatic ecosystems. Thus, they represent a peculiar set of ecosystems for the study of the origin, processing and fate of DOC in inland waters. We reviewed data from 2 decades of studies on the carbon cycle in these coastal lagoons and discussed the fluctuations in the concentration and quality of DOC, factors affecting DOC microbial and photochemical degradation, CO2 emission, as well as the role of humic and non-humic carbon to the energy flow through the trophic chains. We show that DOC quality, not its quantity, determines the rates of photochemical and microbial degradation both seasonally (within system and spatially (among systems, with the exception of DOC photo-oxidation among lagoons, which is partially explained by DOC concentration at regional scale. In humic lagoons, there is a fairly predictable pattern of seasonal variation in DOC concentration associated to rainfall-induced inputs of allochthonous C. However, little is known about the exact timing of these allochthonous inputs and how they relate to the seasonal variation of DOC chemical properties (i.e. its quality. Depth-integrated photo-oxidation rates were less representative in highly humic lagoons, due to strong light attenuation in the water column. Nevertheless, the potential contribution of photo-oxidation and bacterial respiration to total CO2 efflux (~11% did not differ significantly when all lagoons were pooled together. Contrary to prevailing paradigms for humic waters, microalgae seem to be the main C source in humic lagoons, sustaining pelagic food webs through zooplankton, in spite of some contribution of allochthonous C. Thus, the predominant role of the microbial loop in the DOC recovery to food webs in such systems is to be questioned.

  20. New pyrolytic and spectroscopic data on Orgueil and Murchison insoluble organic matter: A different origin than soluble?

    Science.gov (United States)

    Remusat, Laurent; Derenne, Sylvie; Robert, François; Knicker, Heike

    2005-08-01

    Pyrolysis with and without tetramethylammonium hydroxide (TMAH), vacuum pyrolysis, and solid state 15N nuclear magnetic resonance (NMR) were used to examine the macromolecular insoluble organic matter (IOM) from the Orgueil and Murchison meteorites. Conventional pyrolysis reveals a set of poorly functionalized aromatic compounds, ranging from one to four rings and with random methyl substitutions. These compounds are in agreement with spectroscopic and pyrolytic results previously reported. For the first time, TMAH thermochemolysis was used to study extraterrestrial material. The detection of aromatics bearing methyl esters and methoxy groups reveals the occurrence of ester and ether bridges between aromatic units in the macromolecular network. No nitrogen-containing compounds were detected with TMAH thermochemolysis, although they are a common feature in terrestrial samples. Along with vacuum pyrolysis results, thermochemolysis shows that nitrogen is probably sequestered in condensed structures like heterocyclic aromatic rings, unlike oxygen, which is mainly located within linkages between aromatic units. This is confirmed by solid state 15N NMR performed on IOM from Orgueil, showing that nitrogen is present in pyrrole, indole, and carbazole moieties. These data show that amino acids are neither derived from the hydrolysis of IOM nor from a common precursor. In order to reconcile the literature isotopic data and the present molecular results, it is proposed that aldehydes and ketones (1) originated during irradiation of ice in space and (2) were then mobilized during the planetesimal hydrothermalism, yielding the formation of amino acids. If correct, prebiotic molecules are the products of the subsurface chemistry of planetesimals and are thus undetectable through astronomical probes.

  1. Prenatal development supports a single origin of laryngeal echolocation in bats.

    Science.gov (United States)

    Wang, Zhe; Zhu, Tengteng; Xue, Huiling; Fang, Na; Zhang, Junpeng; Zhang, Libiao; Pang, Jian; Teeling, Emma C; Zhang, Shuyi

    2017-01-09

    Bat laryngeal echolocation is considered as one of the most complex and diverse modes of auditory sensory perception in animals and its evolutionary history has been the cause of many scientific controversies in the past two decades. To date, the majority of scientific evidence supports that bats (Chiroptera) are divided into two subordinal groups: Yinpterochiroptera, containing the laryngeal echolocating superfamily Rhinolophidae as sister taxa to the non-laryngeal echolocating family Pteropodidae; and Yangochiroptera, containing all other laryngeal echolocating lineages. This topology has led to an unanswered question in mammalian biology: was laryngeal echolocation lost in the ancestral pteropodids or gained convergently in the echolocating bat lineages? To date, there is insufficient and conflicting evidence from fossil, genomic, morphological and phylogenomic data to resolve this question. We detail an ontogenetic study of fetal cochlear development from seven species of bats and five outgroup mammals and show that in early fetal development, all bats including the non-laryngeal echolocating pteropodids have a similarly large cochlea typically associated with laryngeal echolocation abilities. The subsequent cochlear growth rate in the pteropodids is the slowest of all mammals and leads to the pteropodids and the non-echolocating lineages eventually sharing a similar cochlear morphospace as adults. The results suggest that pteropodids maintain a vestigial developmental stage indicative of past echolocation capabilities and thus support a single origin of laryngeal echolocation in bats.

  2. [Development of Inhalable Dry Powder Formulations Loaded with Nanoparticles Maintaining Their Original Physical Properties and Functions].

    Science.gov (United States)

    Okuda, Tomoyuki

    2017-01-01

     Functional nanoparticles, such as liposomes and polymeric micelles, are attractive drug delivery systems for solubilization, stabilization, sustained release, prolonged tissue retention, and tissue targeting of various encapsulated drugs. For their clinical application in therapy for pulmonary diseases, the development of dry powder inhalation (DPI) formulations is considered practical due to such advantages as: (1) it is noninvasive and can be directly delivered into the lungs; (2) there are few biocomponents in the lungs that interact with nanoparticles; and (3) it shows high storage stability in the solid state against aggregation or precipitation of nanoparticles in water. However, in order to produce effective nanoparticle-loaded dry powders for inhalation, it is essential to pursue an innovative and comprehensive formulation strategy in relation to composition and powderization which can achieve (1) the particle design of dry powders with physical properties suitable for pulmonary delivery through inhalation, and (2) the effective reconstitution of nanoparticles that will maintain their original physical properties and functions after dissolution of the powders. Spray-freeze drying (SFD) is a relatively new powderization technique combining atomization and lyophilization, which can easily produce highly porous dry powders from an aqueous sample solution. Previously, we advanced the optimization of components and process conditions for the production of SFD powders suitable to DPI application. This review describes our recent results in the development of novel DPI formulations effectively loaded with various nanoparticles (electrostatic nanocomplexes for gene therapy, liposomes, and self-assembled lipid nanoparticles), based on SFD.

  3. Characteristics and development of European cyclones with tropical origin in reanalysis data

    Science.gov (United States)

    Dekker, Mark M.; Haarsma, Reindert J.; Vries, Hylke de; Baatsen, Michiel; Delden, Aarnout J. van

    2018-01-01

    Major storm systems over Europe frequently have a tropical origin. This paper analyses the characteristics and dynamics of such cyclones in the observational record, using MERRA reanalysis data for the period 1979-2013. By stratifying the cyclones along three key phases of their development (tropical phase, extratropical transition and final re-intensification), we identify four radically different life cycles: the tropical cyclone and extratropical cyclone life cycles, the classic extratropical transition and the warm seclusion life cycle. More than 50% of the storms reaching Europe from low latitudes follow the warm seclusion life cycle. It also contains the strongest cyclones. They are characterized by a warm core and a frontal T-bone structure, with a northwestward warm conveyor belt and the effects of dry intrusion. Rapid deepening occurs in the latest phase, around their arrival in Europe. Both baroclinic instability and release of latent heat contribute to the strong intensification. The pressure minimum occurs often a day after entering Europe, which enhances the potential threat of warm seclusion storms for Europe. The impact of a future warmer climate on the development of these storms is discussed.

  4. Cultural Values and Other Perceived Benefits of Organized Activities: A Qualitative Analysis of Mexican-Origin Parents' Perspectives in Arizona

    Science.gov (United States)

    Lin, Alex R.; Simpkins, Sandra D.; Gaskin, Erin R.; Menjívar, Cecilia

    2018-01-01

    The limited understanding on why Latino parents endorse organized activities is problematic given that these beliefs can help elucidate why they overcome barriers to support their children's participation. In this study, we analyzed interviews from a diverse group of 34 Mexican-origin parents who resided in Arizona. Results of the study indicate…

  5. Biological nutrients removal from the supernatant originating from the anaerobic digestion of the organic fraction of municipal solid waste.

    Science.gov (United States)

    Malamis, S; Katsou, E; Di Fabio, S; Bolzonella, D; Fatone, F

    2014-09-01

    This study critically evaluates the biological processes and techniques applied to remove nitrogen and phosphorus from the anaerobic supernatant produced from the treatment of the organic fraction of municipal solid waste (OFMSW) and from its co-digestion with other biodegradable organic waste (BOW) streams. The wide application of anaerobic digestion for the treatment of several organic waste streams results in the production of high quantities of anaerobic effluents. Such effluents are characterized by high nutrient content, because organic and particulate nitrogen and phosphorus are hydrolyzed in the anaerobic digestion process. Consequently, adequate post-treatment is required in order to comply with the existing land application and discharge legislation in the European Union countries. This may include physicochemical and biological processes, with the latter being more advantageous due to their lower cost. Nitrogen removal is accomplished through the conventional nitrification/denitrification, nitritation/denitritation and the complete autotrophic nitrogen removal process; the latter is accomplished by nitritation coupled with the anoxic ammonium oxidation process. As anaerobic digestion effluents are characterized by low COD/TKN ratio, conventional denitrification/nitrification is not an attractive option; short-cut nitrogen removal processes are more promising. Both suspended and attached growth processes have been employed to treat the anaerobic supernatant. Specifically, the sequencing batch reactor, the membrane bioreactor, the conventional activated sludge and the moving bed biofilm reactor processes have been investigated. Physicochemical phosphorus removal via struvite precipitation has been extensively examined. Enhanced biological phosphorus removal from the anaerobic supernatant can take place through the sequencing anaerobic/aerobic process. More recently, denitrifying phosphorus removal via nitrite or nitrate has been explored. The removal of

  6. Trends in Organic Farming Development in Bulgaria: Applying Circular Economy Principles to Sustainable Rural Development

    Directory of Open Access Journals (Sweden)

    Dimitrov Dimitar K.

    2017-05-01

    Full Text Available The paper examines the development of organic farming in Bulgaria through the viewpoint of its links to circular economy concept and its potential to contribute to sustainable rural development. The significant increase in the number of organic operators and areas is analyzed in the context of stable growth in the European sector and worldwide and the increase in consumer demand. Main indicators reported by the Ministry of Agriculture and Food of the Republic of Bulgaria and the support provided by the National Rural Development Program are used to present the characteristics of organic production and agricultural holdings. The advantages of Bulgaria are underlined as a country offering the necessary conditions, along with the main problems in production and marketing. Recommendations are provided for organic sector encouragement as a sustainable business model and an entrepreneurial initiative for sustainable rural development putting a special accent on networking and capacity building activities in connection to potential solutions and policy development.

  7. Fast track developments, Gulf of Mexico -- options and organization

    International Nuclear Information System (INIS)

    Craig, M.J.K.; Carruth, R.E.

    1995-01-01

    The pressure continues to compress the 'idea to barrel' time period -- to get oil and gas from a discovery into the pipeline as quickly, cheaply and safely as possible. This paper discusses the range of development options presently available in the Gulf of Mexico (GoM) to meet these goals, and a project organizational structure that allows for maximum implementation efficiency. The structural options range from a standard 4-pile to a single, freestanding caisson, and the spectrum of 'minimum structures' in between. Developments in water depths of 100 feet and 200 feet are addressed, as are each system's associated costs, relative risks and startup times. Project organization is also addressed in terms of an effective in-house and out-of-house project organizational structure, the necessary attributes of the key members of this organization, and the most effective types of contracting

  8. [Origin and development of pathological anatomy in Trieste: a paradigmatic history].

    Science.gov (United States)

    Melato, M

    1997-10-01

    gave way to a more specialised discipline which was able to transfer--to post-mortem examinations first and soon after to surgically removed tissues--the wealth of notions developed in the middle of the 19th C in the basic sciences of chemistry, microbiology and physiology, as had been advanced by the second founding father of the discipline, Virchow. Trieste, therefore, may be said to offer a unique example of the origins and development of pathologic anatomy in Central Europe. And the recollection of the city's experience promotes, in the modern pathologist, an awareness of belonging to a discipline which has always been the soundest leader in the advancement of medicine.

  9. PERSPECTIVE FOR THE DEVELOPMENT OF ORGANIC FARMING IN LUBUSKIE VOIVODSHIP

    Directory of Open Access Journals (Sweden)

    Jagoda ZBOROWSKA

    2015-07-01

    Full Text Available The paper discusses the problem of the development of organic farming in lubuskie voivodship. Presented in it analysis of changes in this production sector in recent years and identified critical factors for growth for this area of production in the nearest term. In analysis used statistic data coming from public statistics and public institutions dealing with agricul-tural production sector in Poland.

  10. Personalized Development of Human Organs using 3D Printing Technology

    OpenAIRE

    Radenkovic, Dina; Solouk, Atefeh; Seifalian, Alexander

    2015-01-01

    3D printing is a technique of fabricating physical models from a 3D volumetric digital image. The image is sliced and printed using a specific material into thin layers, and successive layering of the material produces a 3D model. It has already been used for printing surgical models for preoperative planning and in constructing personalized prostheses for patients. The ultimate goal is to achieve the development of functional human organs and tissues, to overcome limitations of o...

  11. [The origin, diffusion and development of healing doctrines in medical history--exemplified by homeopathy].

    Science.gov (United States)

    Schmidt, Josef M

    2007-01-01

    As a paradigmatic case study of the origin, spread, and development of medical systems, this paper investigates the 200-years history of homeopathy from different perspectives of medical history. On the basis of new research on Samuel Hahnemann (1755-1843), first, a concise and critical overview on the principles, explanations, and implications of his doctrine is presented. The historical, conceptual, and social background of the founder of homeopathy is then elaborated in terms of history of medicine, science, philosophy, sociology, culture, and ideas, as well as theory of science, theory of communication, and sociology of science. The process of the world wide spread of homeopathy is examined from different points of view, ranging from history of heroes, institutions, professionalisation, politics, economics, religion, and organisations to history of patients, perception, and semiotics. Finally, a comparative approach to the different development and status of homeopathy in different countries results in the extraction of a set of crucial variables, such as charismatic personage, influential patronage, economic sponsorship, political protection, media support, and patients' demand, which might explane a major part of these differences. Eventually, the notorious splits of homeopathy's doctrine suggest the idea that--in analogy to theory of evolution--a variety of concurrent strains (rather than one monolithic block) of a doctrine may prove to be a kind of advantage for survival. In conclusion, acceptance and relevance of medical systems are determined by many factors. Since external ones are usually outweighing internal ones, medical history may offer a broader and more comprehensive understanding of the dynamics of their spread and development than clinical trials and scientific objection alone.

  12. Original Article

    African Journals Online (AJOL)

    Administratör

    Original Article. Prevalence of Gall Bladder Stones among Type 2 Diabetic ... Increasing age, female gender, overweight, familial history of the disease and type 2 diabetes mellitus is all associated ... GBS development in diabetics. An Italian ...

  13. ORIGINAL ARTICLE

    African Journals Online (AJOL)

    User

    UDS Publishers Limited All Right Reserved 2026-6294. ORIGINAL ... Reproductive development and function in human and other ... sulting solution was filtered and left to stand for three days to ..... male rat brain and pituitary. Brain Res 164,.

  14. Sixty years of the Interamerican Society of Psychology (SIP): origins and development.

    Science.gov (United States)

    Gallegos, Miguel

    2013-01-01

    This paper presents a historical overview of the Interamerican Society of Psychology, which was founded on December 17, 1951, in Mexico City. Firstly, the historical circumstances of the foundation period are presented, as well as the people who made this organization possible, and the state of psychology on the American continent at that time. Secondly, the most important activities that the Interamerican Society of Psychology has developed during its 60 years are mentioned, such as the publication of books and scientific journals, the creation of several task forces and the Interamerican Congresses of Psychology. Basically, the purpose of this paper is to review the history of the Interamerican Society of Psychology through the recovery and use of various documentary sources.

  15. Practical process research and development a guide for organic chemists

    CERN Document Server

    Anderson, Neal G

    2014-01-01

    Designed to provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries, this book describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. It describes hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and ""green chemistry."" Second Edition highlights:  Reflects the current thinking in chemical p

  16. Knowledge Management for Nuclear Research and Development Organizations

    International Nuclear Information System (INIS)

    2012-05-01

    This publication elaborates on the role of nuclear knowledge management in a research and development (R and D) context, and on the importance of facilitating innovation and future development of nuclear technologies for nuclear power, its associated fuel cycles and nuclear applications in medicine, industry and agriculture. It highlights aspects including transferring and preserving knowledge, exchanging information, establishing and supporting cooperative networks, and training the next generation of nuclear experts. It concludes with basic concepts, trends and key drivers for nuclear knowledge management to R and D project managers and other workers from nuclear R and D organizations.

  17. Knowledge Management for Nuclear Research and Development Organizations (Russian Edition)

    International Nuclear Information System (INIS)

    2016-01-01

    This publication elaborates on the role of nuclear knowledge management in a research and development (R&D) context, and on the importance of facilitating innovation and future development of nuclear technologies for nuclear power, its associated fuel cycles, and nuclear applications in medicine, industry and agriculture. It highlights aspects such as transferring and preserving knowledge, exchanging information, establishing and supporting cooperative networks, and training the next generation of nuclear experts. It concludes with basic concepts, trends and key drivers for nuclear knowledge management for R&D project managers and other workers from nuclear R&D organizations.

  18. Effect of dissolved organic matter (DOM) of contrasting origins on Cu and Pb speciation and toxicity to Paracentrotus lividus larvae.

    Science.gov (United States)

    Sánchez-Marín, Paula; Santos-Echeandía, Juan; Nieto-Cid, Mar; Alvarez-Salgado, Xosé Antón; Beiras, Ricardo

    2010-01-31

    Water samples of contrasting origin, including natural seawater, two sediment elutriates and sewage-influenced seawater, were collected and obtained to examine the effect of the dissolved organic matter (DOM) present on metal bioavailability. The carbon content (DOC) and the optical properties (absorbance and fluorescence) of the coloured DOM fraction (CDOM) of these materials were determined. Cu and Pb complexation properties were measured by anodic stripping voltammetry (ASV) and the effect of DOM on Cu and Pb bioavailability was studied by means of the Paracentrotus lividus embryo-larval bioassay. Sediment elutriates and sewage-influenced water (1) were enriched 1.4-1.7 times in DOC; (2) absorbed and reemitted more light; and (3) presented higher Cu complexation capacities (L(Cu)) than the natural seawater used for their preparation. L(Cu) varied from 0.08 microM in natural seawater to 0.3 and 0.5 microM in sediment elutriates and sewage-influenced water, respectively. Differences in DOC, CDOM and Cu complexation capacities were reflected in Cu toxicity. DOM enriched samples presented a Cu EC(50) of 0.64 microM, significantly higher than the Cu EC(50) of natural and artificial seawater, which was 0.38 microM. The protecting effect of DOM on Cu toxicity greatly disappeared when the samples were irradiated with high intensity UV-light. Cu toxicity could be successfully predicted considering ASV-labile Cu concentrations in the samples. Pb complexation by DOM was only detected in the DOM-enriched samples and caused little effect on Pb EC(50). This effect was contrary for both elutriates: one elutriate reduced Pb toxicity in comparison with the control artificial seawater, while the other increased it. UV irradiation of the samples caused a marked increase in Pb toxicity, which correlated with the remaining DOC concentration. DOM parameters were related to Cu speciation and toxicity: good correlations were found between DOC and Cu EC(50), while L(Cu) correlated

  19. Effect of dissolved organic matter (DOM) of contrasting origins on Cu and Pb speciation and toxicity to Paracentrotus lividus larvae

    International Nuclear Information System (INIS)

    Sanchez-Marin, Paula; Santos-Echeandia, Juan; Nieto-Cid, Mar; Alvarez-Salgado, Xose Anton; Beiras, Ricardo

    2010-01-01

    Water samples of contrasting origin, including natural seawater, two sediment elutriates and sewage-influenced seawater, were collected and obtained to examine the effect of the dissolved organic matter (DOM) present on metal bioavailability. The carbon content (DOC) and the optical properties (absorbance and fluorescence) of the coloured DOM fraction (CDOM) of these materials were determined. Cu and Pb complexation properties were measured by anodic stripping voltammetry (ASV) and the effect of DOM on Cu and Pb bioavailability was studied by means of the Paracentrotus lividus embryo-larval bioassay. Sediment elutriates and sewage-influenced water (1) were enriched 1.4-1.7 times in DOC; (2) absorbed and reemitted more light; and (3) presented higher Cu complexation capacities (L Cu ) than the natural seawater used for their preparation. L Cu varied from 0.08 μM in natural seawater to 0.3 and 0.5 μM in sediment elutriates and sewage-influenced water, respectively. Differences in DOC, CDOM and Cu complexation capacities were reflected in Cu toxicity. DOM enriched samples presented a Cu EC 50 of 0.64 μM, significantly higher than the Cu EC 50 of natural and artificial seawater, which was 0.38 μM. The protecting effect of DOM on Cu toxicity greatly disappeared when the samples were irradiated with high intensity UV-light. Cu toxicity could be successfully predicted considering ASV-labile Cu concentrations in the samples. Pb complexation by DOM was only detected in the DOM-enriched samples and caused little effect on Pb EC 50 . This effect was contrary for both elutriates: one elutriate reduced Pb toxicity in comparison with the control artificial seawater, while the other increased it. UV irradiation of the samples caused a marked increase in Pb toxicity, which correlated with the remaining DOC concentration. DOM parameters were related to Cu speciation and toxicity: good correlations were found between DOC and Cu EC 50 , while L Cu correlated better with the

  20. Effect of dissolved organic matter (DOM) of contrasting origins on Cu and Pb speciation and toxicity to Paracentrotus lividus larvae

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez-Marin, Paula, E-mail: paulasanchez@uvigo.es [Laboratorio de Ecoloxia Marina (LEM), Universidade de Vigo, Campus Universitario, 36310 Vigo, Galicia (Spain); Santos-Echeandia, Juan; Nieto-Cid, Mar; Alvarez-Salgado, Xose Anton [Instituto de Investigacions Marinas, Consejo Superior de Investigaciones Cientificas (CSIC), Eduardo Cabello 6, 36208 Vigo, Galicia (Spain); Beiras, Ricardo [Laboratorio de Ecoloxia Marina (LEM), Universidade de Vigo, Campus Universitario, 36310 Vigo, Galicia (Spain)

    2010-01-31

    Water samples of contrasting origin, including natural seawater, two sediment elutriates and sewage-influenced seawater, were collected and obtained to examine the effect of the dissolved organic matter (DOM) present on metal bioavailability. The carbon content (DOC) and the optical properties (absorbance and fluorescence) of the coloured DOM fraction (CDOM) of these materials were determined. Cu and Pb complexation properties were measured by anodic stripping voltammetry (ASV) and the effect of DOM on Cu and Pb bioavailability was studied by means of the Paracentrotus lividus embryo-larval bioassay. Sediment elutriates and sewage-influenced water (1) were enriched 1.4-1.7 times in DOC; (2) absorbed and reemitted more light; and (3) presented higher Cu complexation capacities (L{sub Cu}) than the natural seawater used for their preparation. L{sub Cu} varied from 0.08 {mu}M in natural seawater to 0.3 and 0.5 {mu}M in sediment elutriates and sewage-influenced water, respectively. Differences in DOC, CDOM and Cu complexation capacities were reflected in Cu toxicity. DOM enriched samples presented a Cu EC{sub 50} of 0.64 {mu}M, significantly higher than the Cu EC{sub 50} of natural and artificial seawater, which was 0.38 {mu}M. The protecting effect of DOM on Cu toxicity greatly disappeared when the samples were irradiated with high intensity UV-light. Cu toxicity could be successfully predicted considering ASV-labile Cu concentrations in the samples. Pb complexation by DOM was only detected in the DOM-enriched samples and caused little effect on Pb EC{sub 50}. This effect was contrary for both elutriates: one elutriate reduced Pb toxicity in comparison with the control artificial seawater, while the other increased it. UV irradiation of the samples caused a marked increase in Pb toxicity, which correlated with the remaining DOC concentration. DOM parameters were related to Cu speciation and toxicity: good correlations were found between DOC and Cu EC{sub 50}, while L

  1. On the Ethnic Origins of African Development: Chiefs and Precolonial Political Centralization

    Science.gov (United States)

    Michalopoulos, Stelios; Papaioannou, Elias

    2015-01-01

    We report on recent findings of a fruitful research agenda that explores the importance of ethnic-specific traits in shaping African development. First, using recent surveys from Sub-Saharan African countries, we document that individuals identify with their ethnic group as often as with the nation pointing to the salience of ethnicity. Second, we focus on the various historical and contemporary functions of tribal leaders (chiefs) and illustrate their influence on various aspects of the economy and the polity. Third, we elaborate on a prominent dimension of ethnicity, that of the degree of complexity of pre-colonial political organization. Building on insights from the African historiography, we review recent works showing a strong association between pre-colonial centralization and contemporary comparative development both across and within countries. We also document that the link between pre-colonial political centralization and regional development -as captured by satellite images of light density at night-is particularly strong in areas outside the vicinity of the capitals, where due to population mixing and the salience of national institutions ethnic traits play a lesser role. Overall, our evidence is supportive to theories and narratives on the presence of a “dual” economic and institutional environment in Africa. PMID:27011760

  2. The effect of cutting origin and organic plant growth regulator on the growth of Daun Ungu (Graptophyllum pictum) through stem cutting method

    Science.gov (United States)

    Pratama, S. P.; Yunus, A.; Purwanto, E.; Widyastuti, Y.

    2018-03-01

    Graptophyllum pictum is one of medical plants which has important chemical content to treat diseases. Leaf, bark and flower can be used to facilitate menstruation, treat hemorrhoid, constipation, ulcers, ulcers, swelling, and earache. G. pictum is difficult to propagated by seedling due to the long duration of seed formation, thusvegetative propagation is done by stem cutting. The aims of this study are to obtain optimum combination of cutting origin and organic plant growth regulator in various consentration for the growth of Daun Ungu through stem cutting method. This research was conducted at Research center for Medicinal Plant and Traditional DrugTanjungsari, Tegal Gede, Karanganyar in June to August 2016. Origin of cuttings and organic plant growth regulator were used as treatments factor. A completely randomized design (RAL) is used and data were analyzed by F test (ANOVA) with a confidence level of 95%. Any significant differences among treatment followed with Duncan test at a = 5%. The research indicates that longest root was resulted from the treatment of 0,5 ml/l of organic plant growth regulator. The treatment of 1 ml/l is able to increase the fresh and dry weight of root, treatment of 1,5 ml/l of organic plant growth regulator was able to increase the percentage of growing shoots. Treatment of base part as origin of cuttings increases the length, fresh weight and and dry weight of shoot, increase the number of leaves. Interaction treatment between 1 ml/l consentration of organic plant growth regulator and central part origin of cuttings is capable of increasing the leaf area, whereas treatment without organic plant growth regulator and base part as planting material affects the smallest leaf area.

  3. Origin and Development of Drug Addiction in South Asia with Special Reference to Pakistan

    Directory of Open Access Journals (Sweden)

    Syeda Farhana Sarfaraz

    2011-09-01

    Full Text Available During the course of this search man has extracted opium from poppy plant, cocaine from the leaves of coca bush, and cannabis from the hemp plant. Initially the use of these was only for the purpose of relieving the physical and mental capabilities, and for medicinaland surgical purpose. But the human spirit of innovation must have led to the use of these substances for mood-altering effects and offer an escape from the real and difficult world of existence to a more agreeable world of fantasy. These things are perhaps a few of the oldest natural substances a fewer of the oldest natural substances used by human race.The major purpose of the study is to highlight the origin and development of the drug addiction in the South Asian region, and discover its impacts on Pakistan. The problem of the drug addiction, which once could be learned as a by-product of drug traffickingthroughout Pakistan has become a major challenge for the governments, philanthropists and the social reformers of this age. The present extent of addiction depicts a bleak future for the generation to come, unless a revolutionary, well-coordinated and determined approach is envisaged and implemented.

  4. STRATEGIES FOR ORGANIZING JOBS IN TERMS OF SUSTAINABLE DEVELOPMENT OF ORGANIZATIONS

    Directory of Open Access Journals (Sweden)

    OPREA MIHAELA CIOPI

    2014-05-01

    Full Text Available In the production process, the objectives of sustainable development are: the protecting human health and the environment, the technological restructuring and maintaining the risks under control, waste management, reducing losses. On this line, an important role have the strategies of management that aimed at better organizing of jobs, for assuring labor safety and ergonomics conditions, indicating priorities, understanding the performance indicators, better visibility of workflow and support, using the standards and increasing the visual control, providing feedback. To achieve these objectives can be successfully implemented a number of strategies such as: Kaizen, 5S and Maintenance autonomous, which will be developed in this paper

  5. Personalized development of human organs using 3D printing technology.

    Science.gov (United States)

    Radenkovic, Dina; Solouk, Atefeh; Seifalian, Alexander

    2016-02-01

    3D printing is a technique of fabricating physical models from a 3D volumetric digital image. The image is sliced and printed using a specific material into thin layers, and successive layering of the material produces a 3D model. It has already been used for printing surgical models for preoperative planning and in constructing personalized prostheses for patients. The ultimate goal is to achieve the development of functional human organs and tissues, to overcome limitations of organ transplantation created by the lack of organ donors and life-long immunosuppression. We hypothesized a precision medicine approach to human organ fabrication using 3D printed technology, in which the digital volumetric data would be collected by imaging of a patient, i.e. CT or MRI images followed by mathematical modeling to create a digital 3D image. Then a suitable biocompatible material, with an optimal resolution for cells seeding and maintenance of cell viability during the printing process, would be printed with a compatible printer type and finally implanted into the patient. Life-saving operations with 3D printed implants were already performed in patients. However, several issues need to be addressed before translational application of 3D printing into clinical medicine. These are vascularization, innervation, and financial cost of 3D printing and safety of biomaterials used for the construct. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. [The development of organization of medical social care of adolescents].

    Science.gov (United States)

    Chicherin, L P; Nagaev, R Ia

    2014-01-01

    The model of the subject of the Russian Federation is used to consider means of development of health protection and health promotion in adolescents including implementation of the National strategy of activities in interest of children for 2012-2017 approved by decree No761 of the President of Russia in June 1 2012. The analysis is carried out concerning organization of medical social care to this group of population in medical institutions and organizations of different type in the Republic of Bashkortostan. Nowadays, in 29 territories medical social departments and rooms, 5 specialized health centers for children, 6 clinics friendly to youth are organized. The analysis of manpower support demonstrates that in spite of increasing of number of rooms and departments of medical social care for children and adolescents decreasing of staff jobs both of medical personnel and psychologists and social workers occurs. The differences in priorities of functioning of departments and rooms of medical social care under children polyclinics, health centers for children and clinics friendly to youth are established. The questionnaire survey of pediatricians and adolescents concerning perspectives of development of adolescent service established significant need in development of specialized complex center. At the basis of such center problems of medical, pedagogical, social, psychological, legal profile related to specific characteristics of development and medical social needs of adolescents can be resolved. The article demonstrates organizational form of unification on the functional basis of the department of medical social care of children polyclinic and clinic friendly to youth. During three years, number of visits of adolescents to specialists of the center increases and this testifies awareness of adolescents and youth about activities of department of medical social care. The most percentage of visits of adolescents to specialists was made with prevention purpose. Among

  7. Private sector accountable care organization development: a qualitative study.

    Science.gov (United States)

    Scheck McAlearney, Ann; Hilligoss, Brian; Song, Paula H

    2017-03-01

    To explore accountable care organizations (ACOs) as they develop in the private sector, including their motivation for development, perspectives from consumers regarding these emerging ACOs, and the critical success factors associated with ACO development. Comprehensive organizational case studies of 4 full-risk private sector ACOs that included in-person interviews with providers and administrators and focus groups with local consumers. Sixty-eight key informant interviews conducted during site visits, supplemented by document collection and telephone interviews, and 5 focus groups were held with 52 consumers associated with the study ACOs. We found 3 main motivators for private sector ACO development: 1) opportunity to improve quality and efficiency, 2) potential to improve population health, and 3) belief that payment reform is inevitable. With respect to consumer perspectives, consumers were unaware they received care from an ACO. From the perspectives of ACO stakeholders, these ACOs noted that they prefer to focus on patients' relationships with providers and typically do not emphasize the ACO name or entity. Critical success factors for private sector ACO development included provider engagement, strategic buy-in, prior experience managing risk, IT infrastructure, and leadership, all meant to shift the culture to a focus on value instead of volume. These organizations perceived that pursuing an accountable care strategy allowed them to respond to policy changes anticipated to impact the way healthcare is delivered and reimbursed. Increased understanding of factors that have been important for more mature private sector ACOs may help other healthcare organizations as they strive to enhance value and advance in their ACO journeys.

  8. NASA's Physics of the Cosmos and Cosmic Origins programs manage Strategic Astrophysics Technology (SAT) development

    Science.gov (United States)

    Pham, Thai; Thronson, Harley; Seery, Bernard; Ganel, Opher

    2016-07-01

    The strategic astrophysics missions of the coming decades will help answer the questions "How did our universe begin and evolve?" "How did galaxies, stars, and planets come to be?" and "Are we alone?" Enabling these missions requires advances in key technologies far beyond the current state of the art. NASA's Physics of the Cosmos2 (PCOS), Cosmic Origins3 (COR), and Exoplanet Exploration Program4 (ExEP) Program Offices manage technology maturation projects funded through the Strategic Astrophysics Technology (SAT) program to accomplish such advances. The PCOS and COR Program Offices, residing at the NASA Goddard Space Flight Center (GSFC), were established in 2011, and serve as the implementation arm for the Astrophysics Division at NASA Headquarters. We present an overview of the Programs' technology development activities and the current technology investment portfolio of 23 technology advancements. We discuss the process for addressing community-provided technology gaps and Technology Management Board (TMB)-vetted prioritization and investment recommendations that inform the SAT program. The process improves the transparency and relevance of our technology investments, provides the community a voice in the process, and promotes targeted external technology investments by defining needs and identifying customers. The Programs' priorities are driven by strategic direction from the Astrophysics Division, which is informed by the National Research Council's (NRC) "New Worlds, New Horizons in Astronomy and Astrophysics" (NWNH) 2010 Decadal Survey report [1], the Astrophysics Implementation Plan (AIP) [2] as updated, and the Astrophysics Roadmap "Enduring Quests, Daring Visions" [3]. These priorities include technology development for missions to study dark energy, gravitational waves, X-ray and inflation probe science, and large far-infrared (IR) and ultraviolet (UV)/optical/IR telescopes to conduct imaging and spectroscopy studies. The SAT program is the

  9. NASA's Physics of the Cosmos and Cosmic Origins Technology Development Programs

    Science.gov (United States)

    Pham, Thai; Seery, Bernard; Ganel, Opher

    2016-01-01

    The strategic astrophysics missions of the coming decades will help answer the questions "How did our universe begin and evolve?" and "How did galaxies, stars, and planets come to be?" Enabling these missions requires advances in key technologies far beyond the current state of the art. NASA's Physics of the Cosmos (PCOS) and Cosmic Origins (COR) Program Offices manage technology maturation projects funded through the Strategic Astrophysics Technology (SAT) program to accomplish such advances. The PCOS and COR Program Offices, residing at the NASA Goddard Space Flight Center (GSFC), were established in 2011, and serve as the implementation arm for the Astrophysics Division at NASA Headquarters. We present an overview of the Programs' technology development activities and the current technology investment portfolio of 23 technology advancements. We discuss the process for addressing community-provided technology gaps and Technology Management Board (TMB)-vetted prioritization and investment recommendations that inform the SAT program. The process improves the transparency and relevance of our technology investments, provides the community a voice in the process, and promotes targeted external technology investments by defining needs and identifying customers. The Programs' priorities are driven by strategic direction from the Astrophysics Division, which is informed by the National Research Council's (NRC) "New Worlds, New Horizons in Astronomy and Astrophysics" (NWNH) 2010 Decadal Survey report [1], the Astrophysics Implementation Plan (AIP) [2] as updated, and the Astrophysics Roadmap "Enduring Quests, Daring Visions" [3]. These priorities include technology development for missions to study dark energy, gravitational waves, X-ray and inflation probe science, and large far-infrared (IR) and ultraviolet (UV)/optical/IR telescopes to conduct imaging and spectroscopy studies. The SAT program is the Astrophysics Division's main investment method to mature technologies

  10. Characterization and quantification by mass spectrometry of mobile organic matter from clay rock: influence of the origin and of the sampling

    International Nuclear Information System (INIS)

    Huclier-Markai, S.; Landesman, C.; Montavon, G.; Grambow, B.; Monteau, F.; Fernandez, A.M.; Vinsot, A.

    2012-01-01

    Document available in extended abstract form only. In environmental studies, Natural Organic Matter (NOM) plays a key role on the bioavailability and the toxicity of metallic compounds. If one wants to evaluate the mobility of heavy metals / radionuclides, which is in natura in most of the cases dependant on their interactions with NOM. One part of the organic inventory in the Callovo-Oxfordian formation (COx) exists as small dissolved compounds in the pore water but the weak content and the weak porosity of the formation (∼ 8 % of water in weight) make the complexation study with metal ions difficult. One part of the organic matter attached to the sediment (∼ 1 % in weight) can be mobilized in a synthetic pore water 1 and can be considered as similar to in situ pore water dissolved organic matter (DOM) regarding its size distribution. The collection of clay pore water has been done through percolation experiment, a unique and original experimental process developed to get pore water from a core sample,that have been described previously. From these experiments, it was shown that mobile organic matter concentration could reach 0.01 mol C/L by application of a pressure gradient up to 100 bars. Since part of the OM from the COx is known to be sensitive to air oxidation, the characterization and quantification of DOM were then performed under anoxic conditions (about - 170 mV vs Standard Hydrogen Electrode SHE). In addition, the chemical composition of NOM contained in the pore water from the argillite clay rock has been determined in in-situ like conditions by ESI-MS and APCI-MS, which are suitable techniques to identify the chemical composition of NOM contained in the COx pore water available from boreholes. Mostly low molecular weight molecules were identified, of whom structural features observed were mainly acidic compounds, fatty acids as well as aldehydes and amino acids. Fulvic and Humic Acids have such low concentrations in the COx formation, leading to a

  11. Sordaria macrospora, a model organism to study fungal cellular development.

    Science.gov (United States)

    Engh, Ines; Nowrousian, Minou; Kück, Ulrich

    2010-12-01

    During the development of multicellular eukaryotes, the processes of cellular growth and organogenesis are tightly coordinated. Since the 1940s, filamentous fungi have served as genetic model organisms to decipher basic mechanisms underlying eukaryotic cell differentiation. Here, we focus on Sordaria macrospora, a homothallic ascomycete and important model organism for developmental biology. During its sexual life cycle, S. macrospora forms three-dimensional fruiting bodies, a complex process involving the formation of different cell types. S. macrospora can be used for genetic, biochemical and cellular experimental approaches since diverse tools, including fluorescence microscopy, a marker recycling system and gene libraries, are available. Moreover, the genome of S. macrospora has been sequenced and allows functional genomics analyses. Over the past years, our group has generated and analysed a number of developmental mutants which has greatly enhanced our fundamental understanding about fungal morphogenesis. In addition, our recent research activities have established a link between developmental proteins and conserved signalling cascades, ultimately leading to a regulatory network controlling differentiation processes in a eukaryotic model organism. This review summarizes the results of our recent findings, thus advancing current knowledge of the general principles and paradigms underpinning eukaryotic cell differentiation and development. Copyright © 2010 Elsevier GmbH. All rights reserved.

  12. Medical staff organization in nursing homes: scale development and validation.

    Science.gov (United States)

    Katz, Paul R; Karuza, Jurgis; Intrator, Orna; Zinn, Jacqueline; Mor, Vincent; Caprio, Thomas; Caprio, Anthony; Dauenhauer, Jason; Lima, Julie

    2009-09-01

    To construct a multidimensional self-report scale to measure nursing home (NH) medical staff organization (NHMSO) dimensions and then pilot the scale using a national survey of medical directors to provide data on its psychometric properties. Instrument development process consisting of the proceedings from the Nursing Home Physician Workforce Conference and focus groups followed by cognitive interviews, which culminated in a survey of a random sample of American Medical Directors Association (AMDA) affiliated medical directors. Analyses were conducted on surveys matched to Online Survey Certification and Reporting (OSCAR) data from freestanding nonpediatric nursing homes. A total of 202 surveys were available for analysis and comprised the final sample. Dimensions were identified that measured the extent of medical staff organization in nursing homes and included staff composition, appointment process, commitment (physiciancohesion; leadership turnover/capability), departmentalization (physician supervision, autonomy and interdisciplinary involvement), documentation, and informal dynamics. The items developed to measure each dimension were reliable (Cronbach's alpha ranged from 0.81 to 0.65).Intercorrelations among the scale dimensions provided preliminary evidence of the construct validity of the scale. This report, for the first time ever, defines and validates NH medical staff organization dimensions, a critical first step in determining the relationship between physician practice and the quality of care delivered in the NH.

  13. Extended precision data types for the development of the original computer aided engineering applications

    Science.gov (United States)

    Pescaru, A.; Oanta, E.; Axinte, T.; Dascalescu, A.-D.

    2015-11-01

    paper is the design of a library which includes the optimized solutions previously tested, that may be used for the easily development of original CAE cross-platform applications. Last but not least, beside the generality of the data type solutions, there is targeted the development of a software library which may be used for the easily development of node-based CAE applications, each node having several known or unknown parameters, the system of equations being automatically generated and solved.

  14. Development of the retinotopic organization in Salmo gairdneri

    International Nuclear Information System (INIS)

    Pinganaud, G.

    1987-01-01

    The progression of the retinotopic organization in the optic nerve projections to the contralateral thalamus and tectum was studied in Salmo gairdneri from hatching stage to 3 month old stage. After quadratic lesions of the temporal, dorsal, nasal, or ventral retina, the animals were separated in two groups: one used for Fink and Heimer method or electron microscopic observation and the other one for radioautography after injection in the operated eye of [ 14 C] or [ 3 H]proline. The analysis of the projections of each retinal quadrant revealed: (1) Projections to thalamus and pretectum are ignorganized and appear progressively during development. On the contrary in tectum and corpus geniculatum, the visual projections are retinotopically organized since hatching. (2) In the whole retino-tectal system, two subsystems develop differently: the naso-ventral retina reaches precociously its permanent target (the posterior tectum), the temporo-dorsal part of the retina links to the anterior tectum and shifts laterally during the first month after hatching, from medial to antero-lateral for temporal projections. The shifting of projections is correlated with development of the medial fascicle of the optic tract. So it appears that the pathways play an important role in the spatio-temporal ordered pattern of terminations of retinal fibers on the tectal surface during development. (author)

  15. Development of sorbent therapy for multiple organ dysfunction syndrome (MODS)

    International Nuclear Information System (INIS)

    Li Li; Pan Jilun; Yu Yaoting

    2007-01-01

    As a syndrome, multiple organ dysfunction (MODS) is defined as an altered organ function in the setting of sepsis, septic shock or systemic inflammatory response syndrome (SIRS) and is the most common cause of death in intensive care units. Endotoxin, a constituent of cell walls of Gram-negative bacteria, plays an important role in the initiation and development of MODS. The cytokines, especially tumor necrosis factor alpha (TNF-alpha), are early regulators of the immune response and can induce the release of secondary cytokines. To remove endotoxin and TNF-alpha from patients with MODS, the adsorption method has proven to be most effective. In this review, we provide various methods of removal of endotoxins and TNF-alpha using different adsorbents. (topical review)

  16. Development of immune organs and functioning in humans and test animals: Implications for immune intervention studies.

    Science.gov (United States)

    Kuper, C Frieke; van Bilsen, Jolanda; Cnossen, Hilde; Houben, Geert; Garthoff, Jossie; Wolterbeek, Andre

    2016-09-01

    A healthy immune status is mostly determined during early life stages and many immune-related diseases may find their origin in utero and the first years of life. Therefore, immune health optimization may be most effective during early life. This review is an inventory of immune organ maturation events in relation to developmental timeframes in minipig, rat, mouse and human. It is concluded that time windows of immune organ development in rodents can be translated to human, but minipig reflects the human timeframes better; however the lack of prenatal maternal-fetal immune interaction in minipig may cause less responsiveness to prenatal intervention. It is too early to conclude which immune parameters are most appropriate, because there are not enough comparative immune parameters. Filling these gaps will increase the predictability of results observed in experimental animals, and guide future intervention studies by assessing relevant parameters in the right corresponding developmental time frames. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Functional brain networks develop from a "local to distributed" organization.

    Directory of Open Access Journals (Sweden)

    Damien A Fair

    2009-05-01

    Full Text Available The mature human brain is organized into a collection of specialized functional networks that flexibly interact to support various cognitive functions. Studies of development often attempt to identify the organizing principles that guide the maturation of these functional networks. In this report, we combine resting state functional connectivity MRI (rs-fcMRI, graph analysis, community detection, and spring-embedding visualization techniques to analyze four separate networks defined in earlier studies. As we have previously reported, we find, across development, a trend toward 'segregation' (a general decrease in correlation strength between regions close in anatomical space and 'integration' (an increased correlation strength between selected regions distant in space. The generalization of these earlier trends across multiple networks suggests that this is a general developmental principle for changes in functional connectivity that would extend to large-scale graph theoretic analyses of large-scale brain networks. Communities in children are predominantly arranged by anatomical proximity, while communities in adults predominantly reflect functional relationships, as defined from adult fMRI studies. In sum, over development, the organization of multiple functional networks shifts from a local anatomical emphasis in children to a more "distributed" architecture in young adults. We argue that this "local to distributed" developmental characterization has important implications for understanding the development of neural systems underlying cognition. Further, graph metrics (e.g., clustering coefficients and average path lengths are similar in child and adult graphs, with both showing "small-world"-like properties, while community detection by modularity optimization reveals stable communities within the graphs that are clearly different between young children and young adults. These observations suggest that early school age children and adults

  18. Functional brain networks develop from a "local to distributed" organization.

    Science.gov (United States)

    Fair, Damien A; Cohen, Alexander L; Power, Jonathan D; Dosenbach, Nico U F; Church, Jessica A; Miezin, Francis M; Schlaggar, Bradley L; Petersen, Steven E

    2009-05-01

    The mature human brain is organized into a collection of specialized functional networks that flexibly interact to support various cognitive functions. Studies of development often attempt to identify the organizing principles that guide the maturation of these functional networks. In this report, we combine resting state functional connectivity MRI (rs-fcMRI), graph analysis, community detection, and spring-embedding visualization techniques to analyze four separate networks defined in earlier studies. As we have previously reported, we find, across development, a trend toward 'segregation' (a general decrease in correlation strength) between regions close in anatomical space and 'integration' (an increased correlation strength) between selected regions distant in space. The generalization of these earlier trends across multiple networks suggests that this is a general developmental principle for changes in functional connectivity that would extend to large-scale graph theoretic analyses of large-scale brain networks. Communities in children are predominantly arranged by anatomical proximity, while communities in adults predominantly reflect functional relationships, as defined from adult fMRI studies. In sum, over development, the organization of multiple functional networks shifts from a local anatomical emphasis in children to a more "distributed" architecture in young adults. We argue that this "local to distributed" developmental characterization has important implications for understanding the development of neural systems underlying cognition. Further, graph metrics (e.g., clustering coefficients and average path lengths) are similar in child and adult graphs, with both showing "small-world"-like properties, while community detection by modularity optimization reveals stable communities within the graphs that are clearly different between young children and young adults. These observations suggest that early school age children and adults both have

  19. A transcriptomics investigation into pine reproductive organ development.

    Science.gov (United States)

    Niu, Shihui; Yuan, Huwei; Sun, Xinrui; Porth, Ilga; Li, Yue; El-Kassaby, Yousry A; Li, Wei

    2016-02-01

    The development of reproductive structures in gymnosperms is still poorly studied because of a lack of genomic information and useful genetic tools. The hermaphroditic reproductive structure derived from unisexual gymnosperms is an even less studied aspect of seed plant evolution. To extend our understanding of the molecular mechanism of hermaphroditism and the determination of sexual identity of conifer reproductive structures in general, unisexual and bisexual cones from Pinus tabuliformis were profiled for gene expression using 60K microarrays. Expression patterns of genes during progression of sexual cone development were analysed using RNA-seq. The results showed that, overall, the transcriptomes of male structures in bisexual cones were more similar to those of female cones. However, the expression of several MADS-box genes in the bisexual cones was similar to that of male cones at the more juvenile developmental stage, while despite these expression shifts, male structures of bisexual cones and normal male cones were histologically indistinguishable and cone development was continuous. This study represents a starting point for in-depth analysis of the molecular regulation of cone development and also the origin of hermaphroditism in pine. © 2015 The Authors. New Phytologist © 2015 New Phytologist Trust.

  20. THE DEVELOPMENT OF THE ORGANIC AQUACULTURE. CASE STUDY: ROMANIA

    Directory of Open Access Journals (Sweden)

    Silvius STANCIU

    2015-12-01

    Full Text Available Aquaculture contribute ever more to the production of aquatic food worldwide, even if the sustainable limits for majority of wild fish stocks, are now almost reached or even exceeded. In the EU, aquaculture is an important economic activity in many coastal and continental regions. Aquaculture plays an important role in terms of access to food resources and it is necessary to use its potential to contribute to sustainable development, food security, economic growth and employment. In this regard, starting from EU aquaculture objectives, the paper intend to make an analysis of the national situation of aquaculture and its current potential. The paper presented the progress of Romanian investments in aquaculture, identifying needs and opportunities for the Romanian aquaculture development. Taking into consideration the natural resources available and the growth of global request of organic product, the development of ecologic aquaculture might represent o niche market for local producers.

  1. Development of radiation resistant organic composites for cryogenic use

    International Nuclear Information System (INIS)

    Nishijima, S.

    1997-01-01

    The mechanism of the radiation induced degradation of the mechanical properties in composite materials have been studied and based on the mechanism the radiation resistant organic composites for fusion magnet have been developing. It was found that the degradation was brought by the change of the fracture mode from tensile (or flexural) to shear failure. Consequently the intrinsic parameter which control the degradation was concluded to be the interlaminar shear strength. To develop the radiation resistant composites, therefore, means to develop the composites showing the radiation resistant interlaminar shear strength. The mechanism was confirmed using three dimensional fabric reinforced plastics which do not have the interlaminar area. The roles of matrix in the composites were also revealed. The effects of dose quality and irradiated temperature on the radiation induced degradation were also discussed and the selection standards of the components for radiation resistant composites were proposed

  2. Origin and development of «mcuniversity»: course on economization the educational field

    Directory of Open Access Journals (Sweden)

    M. V. Klyov

    2014-09-01

    Full Text Available The author examines the concept of «McUniversity», introduced in 1995 by British sociologists M.Parker and J.Jary. However, attention is drawn to the concept of McDonaldization, masovization that lead to the emergence of phenomena of economization in education. It is noted that the principle of McDonaldization is used by the most businesses organizations, and the McDonald’s is the epitome of efficiency, predictability and automation; gradually moving to the University, it manifests itself in rationalization, excessive consumption, the use of advertising, which creates the illusion of consumer cooperation, which focused on human behavior, freedom and impartiality. The article states that the educational sector reformers often confuse economization of education and its commercialization. The processes of economization of education are one of the most important factors of economic development and cause change. After all, education is increasingly starting to be not as education for education and obtain «pure knowledge», namely as a powerful fact of development that allows countries to enter new innovative technological frontier. In general, education is seen as a major factor of social and economic progress and stability of the social system. So the concept of «McUniversity», introduced in 1995, is becoming increasingly important today, setting the stage for the development of the economization of education in our society, because the modern era characterized rankings of universities and faculties at the international and national levels, strengthening the competitive spirit among faculties and tutors, establishing schools and faculties that operate as businesses due to the fact that they perform managerial principles.

  3. Origin of the Strong Interaction between Polar Molecules and Copper(II) Paddle-Wheels in Metal Organic Frameworks.

    Science.gov (United States)

    Ongari, Daniele; Tiana, Davide; Stoneburner, Samuel J; Gagliardi, Laura; Smit, Berend

    2017-07-20

    The copper paddle-wheel is the building unit of many metal organic frameworks. Because of the ability of the copper cations to attract polar molecules, copper paddle-wheels are promising for carbon dioxide adsorption and separation. They have therefore been studied extensively, both experimentally and computationally. In this work we investigate the copper-CO 2 interaction in HKUST-1 and in two different cluster models of HKUST-1: monocopper Cu(formate) 2 and dicopper Cu 2 (formate) 4 . We show that density functional theory methods severely underestimate the interaction energy between copper paddle-wheels and CO 2 , even including corrections for the dispersion forces. In contrast, a multireference wave function followed by perturbation theory to second order using the CASPT2 method correctly describes this interaction. The restricted open-shell Møller-Plesset 2 method (ROS-MP2, equivalent to (2,2) CASPT2) was also found to be adequate in describing the system and used to develop a novel force field. Our parametrization is able to predict the experimental CO 2 adsorption isotherms in HKUST-1, and it is shown to be transferable to other copper paddle-wheel systems.

  4. Dormant origins as a built-in safeguard in eukaryotic DNA replication against genome instability and disease development.

    Science.gov (United States)

    Shima, Naoko; Pederson, Kayla D

    2017-08-01

    DNA replication is a prerequisite for cell proliferation, yet it can be increasingly challenging for a eukaryotic cell to faithfully duplicate its genome as its size and complexity expands. Dormant origins now emerge as a key component for cells to successfully accomplish such a demanding but essential task. In this perspective, we will first provide an overview of the fundamental processes eukaryotic cells have developed to regulate origin licensing and firing. With a special focus on mammalian systems, we will then highlight the role of dormant origins in preventing replication-associated genome instability and their functional interplay with proteins involved in the DNA damage repair response for tumor suppression. Lastly, deficiencies in the origin licensing machinery will be discussed in relation to their influence on stem cell maintenance and human diseases. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Theory-inspired development of organic electro-optic materials

    Energy Technology Data Exchange (ETDEWEB)

    Dalton, Larry R., E-mail: dalton@chem.washington.ed [Department of Chemistry, Bagley Hall 202D, Box 351700, University of Washington, Seattle, Washington 98195-1700 (United States); Department of Electrical Engineering, Bagley Hall 202D, Box 351700, University of Washington, Seattle, Washington 98195-1700 (United States)

    2009-11-30

    Real-time, time-dependent density functional theory (RTTDDFT) and pseudo-atomistic Monte Carlo-molecular dynamics (PAMCMD) calculations have been used in a correlated manner to achieve quantitative definition of structure/function relationships necessary for the optimization of electro-optic activity in organic materials. Utilizing theoretical guidance, electro-optic coefficients (at telecommunication wavelengths) have been increased to 500 pm/V while keeping optical loss to less than 2 dB/cm. RTTDDFT affords the advantage of permitting explicit treatment of time-dependent electric fields, both applied fields and internal fields. This modification has permitted the quantitative simulation of the variation of linear and nonlinear optical properties of chromophores and the electro-optic activity of materials with optical frequency and dielectric permittivity. PAMCMD statistical mechanical calculations have proven an effective means of treating the full range of spatially-anisotropic intermolecular electrostatic interactions that play critical roles in defining the degree of noncentrosymmetric order that is achieved by electric field poling of organic electro-optic materials near their glass transition temperatures. New techniques have been developed for the experimental characterization of poling-induced acentric order including a modification of variable angle polarization absorption spectroscopy (VAPAS) permitting a meaningful correlation of theoretical and experimental data related to poling-induced order for a variety of complex organic electro-optic materials.

  6. Theory-inspired development of organic electro-optic materials

    International Nuclear Information System (INIS)

    Dalton, Larry R.

    2009-01-01

    Real-time, time-dependent density functional theory (RTTDDFT) and pseudo-atomistic Monte Carlo-molecular dynamics (PAMCMD) calculations have been used in a correlated manner to achieve quantitative definition of structure/function relationships necessary for the optimization of electro-optic activity in organic materials. Utilizing theoretical guidance, electro-optic coefficients (at telecommunication wavelengths) have been increased to 500 pm/V while keeping optical loss to less than 2 dB/cm. RTTDDFT affords the advantage of permitting explicit treatment of time-dependent electric fields, both applied fields and internal fields. This modification has permitted the quantitative simulation of the variation of linear and nonlinear optical properties of chromophores and the electro-optic activity of materials with optical frequency and dielectric permittivity. PAMCMD statistical mechanical calculations have proven an effective means of treating the full range of spatially-anisotropic intermolecular electrostatic interactions that play critical roles in defining the degree of noncentrosymmetric order that is achieved by electric field poling of organic electro-optic materials near their glass transition temperatures. New techniques have been developed for the experimental characterization of poling-induced acentric order including a modification of variable angle polarization absorption spectroscopy (VAPAS) permitting a meaningful correlation of theoretical and experimental data related to poling-induced order for a variety of complex organic electro-optic materials.

  7. 4th International Bulgarian Forum “Origins, Historical Development and Cultural Heritage of Bulgarian Civilization” (Varna, Bulgaria, 22-25 October 2012

    Directory of Open Access Journals (Sweden)

    Khuzin Fayaz Sh.

    2013-03-01

    Full Text Available The work of the 4th International forum "Origins, historical development and cultural heritage of Bulgarian civilization" is highlighted in the article. The forum was organized by the Tatarstan Republican Fund "Vozrozhdenie", Ministries of Culture of the Republic of Bulgaria and the Republic of Tatarstan, the National Archaeological Institute and Museum with the Bulgarian Academy of Sciences, Institute of History named after S. Mardjani, Academy of Sciences of the Republic of Tatarstan, and Varna Regional Historical Museum. It was attended by more than 100 scholars from different research centers of Bulgaria, Russia, Ukraine, Romania, Hungary, and Switzerland. They discussed issues related to the ethnogenesis, ancient and medieval history of the peoples whose origin is connected with the history of the Bulgarians and their state, questions of mutual influence in the field of culture between the Bulgarians and the neighboring peoples, as well as actual problems of cultural heritage study and conservation.

  8. Hiring, Developing, and Organizing Individual Employees for New Product Development versus Product-related Service Innovation

    DEFF Research Database (Denmark)

    Knudsen, Mette Præst; Schleimer, Stephanie

    should be hired. For the latter case, these employees’ individual careers must be developed internally once hired. The paper therefore carries important implication for the innovation management literature and related human resource practices at different organizational levels.......This study examines how manufacturing firms should organize their human resources by maximizing the value of individual employees for different forms of innovations. In particular, it examines the hiring, developing, and structural organization of human resources for optimizing different innovation...... the value of human resource hiring and developing practices for new product development success; organizations will find it more beneficial to invest predominantly in employees with the highest possible educational level, whilst for product-related service innovations; employees with more general skills...

  9. Evolutionary origins and development of saw-teeth on the sawfish and sawshark rostrum (Elasmobranchii; Chondrichthyes).

    Science.gov (United States)

    Welten, Monique; Smith, Moya Meredith; Underwood, Charlie; Johanson, Zerina

    2015-09-01

    A well-known characteristic of chondrichthyans (e.g. sharks, rays) is their covering of external skin denticles (placoid scales), but less well understood is the wide morphological diversity that these skin denticles can show. Some of the more unusual of these are the tooth-like structures associated with the elongate cartilaginous rostrum 'saw' in three chondrichthyan groups: Pristiophoridae (sawsharks; Selachii), Pristidae (sawfish; Batoidea) and the fossil Sclerorhynchoidea (Batoidea). Comparative topographic and developmental studies of the 'saw-teeth' were undertaken in adults and embryos of these groups, by means of three-dimensional-rendered volumes from X-ray computed tomography. This provided data on development and relative arrangement in embryos, with regenerative replacement in adults. Saw-teeth are morphologically similar on the rostra of the Pristiophoridae and the Sclerorhynchoidea, with the same replacement modes, despite the lack of a close phylogenetic relationship. In both, tooth-like structures develop under the skin of the embryos, aligned with the rostrum surface, before rotating into lateral position and then attaching through a pedicel to the rostrum cartilage. As well, saw-teeth are replaced and added to as space becomes available. By contrast, saw-teeth in Pristidae insert into sockets in the rostrum cartilage, growing continuously and are not replaced. Despite superficial similarity to oral tooth developmental organization, saw-tooth spatial initiation arrangement is associated with rostrum growth. Replacement is space-dependent and more comparable to that of dermal skin denticles. We suggest these saw-teeth represent modified dermal denticles and lack the 'many-for-one' replacement characteristic of elasmobranch oral dentitions.

  10. Collaborative Plant Breeding for Organic Agricultural Systems in Developed Countries

    Directory of Open Access Journals (Sweden)

    Isabelle Goldringer

    2011-08-01

    Full Text Available Because organic systems present complex environmental stress, plant breeders may either target very focused regions for different varieties, or create heterogeneous populations which can then evolve specific adaptation through on-farm cultivation and selection. This often leads to participatory plant breeding (PPB strategies which take advantage of the specific knowledge of farmers. Participatory selection requires increased commitment and engagement on the part of the farmers and researchers. Projects may begin as researcher initiatives with farmer participation or farmer initiatives with researcher participation and over time evolve into true collaborations. These projects are difficult to plan in advance because by nature they change to respond to the priorities and interests of the collaborators. Projects need to provide relevant information and analysis in a time-frame that is meaningful for farmers, while remaining scientifically rigorous and innovative. This paper presents two specific studies: the first was a researcher-designed experiment that assessed the potential adaptation of landraces to organic systems through on-farm cultivation and farmer selection. The second is a farmer-led plant breeding project to select bread wheat for organic systems in France. Over the course of these two projects, many discussions among farmers, researchers and farmers associations led to the development of methods that fit the objectives of those involved. This type of project is no longer researcher-led or farmer-led but instead an equal collaboration. Results from the two research projects and the strategy developed for an ongoing collaborative plant breeding project are discussed.

  11. Developing a Climate Change Boundary Organization: the Montana Adaptation Exchange

    Science.gov (United States)

    Whitlock, C. L.; Brooks, S.; Armstrong, T.; Bryan, B.

    2016-12-01

    Small-population large-area states like Montana are often challenged by a need to offer timely and relevant climate-change information that addresses diverse and widely dispersed stakeholder groups. In Montana, filling the gap between science and various types of decision-makers has motivated development of the first Montana Climate Assessment (MCA1), to be released in 2017 with a focus on climate-change impacts for agricultural, water and forestry sectors. To sustain and build on the MCA1 effort, we are also in the process of creating a Boundary Organization (defined by the National Academy of Sciences) called the Montana Adaptation Exchange (the Exchange); this entity will facilitate the flow of information across the boundaries between science, knowledge and implementation. In Montana, the Exchange brings scientists and practitioners together to seek solutions related to climate-change adaptation and other pressing environmental and social-economic challenges. The Montana Adaptation Exchange (1) is a collaborative partnership of members from the science and practitioner communities under a shared governance and participatory model; (2) presents research that has been vetted by the scientific community at large and represents the current state of knowledge; (3) allows for revision and expansion of assessments like the MCA; (4) communicates relevant, often technical, research and findings to a wide variety of resource managers and other stakeholders; (5) develops and maintains an extensive online database that organizes, regularly updates, and makes research data products readily available; and (6) offers an online portal and expert network of affiliated researchers and climate adaptation specialists to provide effective customer support. Boundary organizations, such as the Montana Adaptation Exchange, offer a scalable path to effectively move from "science to knowledge to action" while also allowing stakeholder needs to help inform research agendas.

  12. Insights to develop privacy policy for organization in Indonesia

    Science.gov (United States)

    Rosmaini, E.; Kusumasari, T. F.; Lubis, M.; Lubis, A. R.

    2018-03-01

    Nowadays, the increased utilization of shared application in the network needs not only dictate to have enhanced security but also emphasize the need to balance its privacy protection and ease of use. Meanwhile, its accessibility and availability as the demand from organization service put privacy obligations become more complex process to be handled and controlled. Nonetheless, the underlying principles for privacy policy exist in Indonesian current laws, even though they spread across various article regulations. Religions, constitutions, statutes, regulations, custom and culture requirements still become the reference model to control the activity process for data collection and information sharing accordingly. Moreover, as the customer and organization often misinterpret their responsibilities and rights in the business function, process and level, the essential thing to be considered for professionals on how to articulate clearly the rules that manage their information gathering and distribution in a manner that translates into information system specification and requirements for developers and managers. This study focus on providing suggestion and recommendation to develop privacy policy based on descriptive analysis of 791 respondents on personal data protection in accordance with political and economic factor in Indonesia.

  13. Self-organized criticality in developing neuronal networks.

    Directory of Open Access Journals (Sweden)

    Christian Tetzlaff

    Full Text Available Recently evidence has accumulated that many neural networks exhibit self-organized criticality. In this state, activity is similar across temporal scales and this is beneficial with respect to information flow. If subcritical, activity can die out, if supercritical epileptiform patterns may occur. Little is known about how developing networks will reach and stabilize criticality. Here we monitor the development between 13 and 95 days in vitro (DIV of cortical cell cultures (n = 20 and find four different phases, related to their morphological maturation: An initial low-activity state (≈19 DIV is followed by a supercritical (≈20 DIV and then a subcritical one (≈36 DIV until the network finally reaches stable criticality (≈58 DIV. Using network modeling and mathematical analysis we describe the dynamics of the emergent connectivity in such developing systems. Based on physiological observations, the synaptic development in the model is determined by the drive of the neurons to adjust their connectivity for reaching on average firing rate homeostasis. We predict a specific time course for the maturation of inhibition, with strong onset and delayed pruning, and that total synaptic connectivity should be strongly linked to the relative levels of excitation and inhibition. These results demonstrate that the interplay between activity and connectivity guides developing networks into criticality suggesting that this may be a generic and stable state of many networks in vivo and in vitro.

  14. The Training Process of the Organization Development and Training Office

    Science.gov (United States)

    Johnson, Melissa S.

    2004-01-01

    The Organization Development and Training Office provides training and development opportunities to employees at NASA Glenn Research Center, as a division of the Office of Human Resources and Workforce Planning. Center-wide required trainings, new employee trainings, workshops and career development programs are organized by the OD&TO staff. They also arrange all academic, non-academic, headquarters, fellowship and learning center sponsored courses. They also service organizations wishing to work more effectively by facilitating teambuilding exercises. Equal Opportunity programs and upward mobility programs such as the STEP and GO programs for administrative staff. In working with my mentor I am very involved with Cuyahoga Community College classes, mandatory supervisory training and administrative staff workshops. My largest tasks are in the secretarial training category. The Supporting Organizations And Relationships workshop for administrative personnel, commonly known as SOAR, began last year and continued this summer with follow-up workshops. Months before a workshop or class is brought to Glenn, a need has to be realized. In this case, administrative staff did not feel they had an opportunity to receive relevant training and develop skills through teambuilding, networking and communication. A Statement of work is then created as several companies are contacted about providing the training. After the company best suited to meet the target group s needs is selected, the course is announced with an outline of all pertinent information. A reservation for a facility is made and applications or nominations, depending on the announcement s guidelines, are received from interested employees. Confirmations are sent to participants and final preparations are made but there are still several concluding steps. A training office staff member also assists the facilitator with setting up the facility and introducing the class. After the class, participants evaluations are

  15. International Organizations: the Main Factors of Emergence and Development

    Directory of Open Access Journals (Sweden)

    Lev S. Voronkov

    2015-01-01

    Full Text Available The author argues that the emergence of the first permanent intergovernmental (IIGO and non-governmental (INGO organizationsin the second half of the XIX-th century was due to common causes. He tries to justify the need to consider them not as independent objects of study, but as the phenomenon, caused by the high level of internationalization of economic life of states and of socio-economic consequences of the industrial revolution, reached in this period. The emergence of IIGOs, based on international treaty, was accompanied by establishment of a large number of INGOs operating in similar fields of human activity, which performed supplementary functions and regulated areas of cooperation and public needs, not covered by interstate agreements. The article presents the main factors that in later stages of internationalization and development of contemporary international relations gave the impetus to emergence and development of international organizations, including the military-technological revolution, that gave birth to mass destruction weapons and avalanche-like growth of the number of human and material losses during wars and military conflicts, the Cold War between world communism and world capitalism, the collapse of the colonial system and formation ofa new main contradiction of the world politics between the "Club of rich countries" and states of the "global periphery", beginning of development of regional integration processes and, finally, the emergence of global problems. The article emphasizes that both IIGOs and INGOs evolved from the supportive tools in implementation of multilateral interaction of sovereign states towards becoming an integral part of contemporary international relations, fulfilling many vital functions of modern human society and its citizens. Given the involvement of the overwhelming majority of modern sovereign states and tens of thousands of civil society organizations in activity of numerical IIGOs and INGOs

  16. Role and organization of a centralized radiopharmacy in developing countries

    International Nuclear Information System (INIS)

    Callahan, R.J.; Mather, S.J.

    1991-01-01

    The concept of sharing radiopharmacy services among several users in a particular geographical region has gained widespread acceptance in many countries, particularly in the United States, as a viable way of reducing costs and increasing efficiency of resource utilization. This has been exemplified by the successful commercialization of this concept by several corporations. This concept is also viable when centralization originates from a public or government institution such as a nuclear research center or university hospital. In developing countries with limited resources, shared radiopharmacy services are especially attractive. The International Atomic Energy Agency has been playing a pivotal role in the implementation of centralized radiopharmacies in developing Member States. This document presents some goals, requirements for space, personnel and equipment for various levels of radiopharmacy service along with a general cost analysis. It is intended that this document be a guide to basic concepts and planning strategies in establishing centralized radiopharmacy services. The diversity of available resources and government regulations must be considered in establishing a specific facility. (author). 3 tabs

  17. The Centennial of Counselor Education: Origin and Early Development of a Discipline

    Science.gov (United States)

    Savickas, Mark L.

    2011-01-01

    July 7, 2011, marks the centennial of counselor education as a formal discipline. In recognition of its 100th birthday, the author of this article describes the origins of the discipline, beginning with its prehistory in the work of Frank Parsons to establish the practice of vocational guidance, describing the 1st course in counselor education at…

  18. The origin, development and a brief appraisal of the doctrine of the ...

    African Journals Online (AJOL)

    2013-03-12

    Mar 12, 2013 ... Faith Tabernacle Church', falls outside the focus of this work. The constitution of the CAC was drafted in 1942 ... Apostolic Church was originally called the Faith Tabernacle.' Again, Alokan's claim (1991:147) that the ..... poison with immunity and the ability to heal the sick. The. CAC Constitution and Doctrine ...

  19. Parent-of-origin and trans-generational germline influences on behavioral development: the interacting roles of mothers, fathers, and grandparents.

    Science.gov (United States)

    Curley, J P; Mashoodh, R

    2010-05-01

    Mothers and fathers do not contribute equally to the development of their offspring. In addition to the differential investment of mothers versus fathers in the rearing of offspring, there are also a number of germline factors that are transmitted unequally from one parent or the other that contribute significantly to offspring development. This article shall review four major sources of such parent-of-origin effects. Firstly, there is increasing evidence that genes inherited on the sex chromosomes including the nonpseudoautosomal part of the Y chromosome that is only inherited from fathers to sons, contribute to brain development and behavior independently of the organizing effects of sex hormones. Secondly, recent work has demonstrated that mitochondrial DNA that is primarily inherited only from mothers may play a much greater than anticipated role in neurobehavioral development. Thirdly, there exists a class of genes known as imprinted genes that are epigenetically silenced when passed on in a parent-of-origin specific manner and have been shown to regulate brain development and a variety of behaviors. Finally, there is converging evidence from several disciplines that environmental variations experienced by mothers and fathers may lead to plasticity in the development and behavior of offspring and that this phenotypic inheritance can be solely transmitted through the germline. Mechanistically, this may be achieved through altered programming within germ cells of the epigenetic status of particular genes such as retrotransposons and imprinted genes or potentially through altered expression of RNAs within gametes.

  20. Fired Up by Commitment, Example, and Values: How High-Performance Organizations Develop Leadership

    National Research Council Canada - National Science Library

    Kersh, Kevin

    2002-01-01

    Each year, organizations big and small, public and private spend tremendous resources on programs to develop leaders that will guide those organizations to success, preferably extraordinary success...

  1. Development of technology performance specifications for volatile organic compounds

    International Nuclear Information System (INIS)

    Purdy, C.; Schutte, W.E.

    1993-01-01

    The Office of Technology Development (OTD) within the Office of Environmental Restoration and Waste Management of the Department of Energy has a mission to deliver needed and usable technologies to its customers. The primary customers are individuals and organizations performing environmental characterization and remediation, waste cleanup, and pollution prevention at DOE sites. DOE faces a monumental task in cleaning up the dozen or so major sites and hundreds of smaller sites that were or are used to produce the US nuclear weapons arsenal and to develop nuclear technologies for national defense and for peaceful purposes. Contaminants and waste materials include the radionuclides associated with nuclear weapons, such as plutonium and tritium, and more common pollutants and wastes of industrial activity such as chromium, chlorinated solvents, and polychlorinated biphenyls (PCBs). Quite frequently hazardous wastes regulated by the Environmental Protection Agency are co-mingled with radioactive wastes regulated by the Nuclear Regulatory Commission to yield a open-quotes mixed waste,close quotes which increases the cleanup challenges from several perspectives. To help OTD and its investigators meet DOE's cleanup goal, technology performance specifications are being implemented for research and development and DT ampersand E projects. Technology performance specifications or open-quotes performance goalsclose quotes describe, quantitatively where possible, the technology development needs being addressed. These specifications are used to establish milestones, evaluate the status of ongoing projects, and determine the success of completed projects

  2. Origin of switching current transients in TIPS-pentacene based organic thin-film transistor with polymer dielectric

    Science.gov (United States)

    Singh, Subhash; Mohapatra, Y. N.

    2017-06-01

    We have investigated switch-on drain-source current transients in fully solution-processed thin film transistors based on 6,13-bis(triisopropylsilylethynyl) pentacene (TIPS-pentacene) using cross-linked poly-4-vinylphenol as a dielectric. We show that the nature of the transient (increasing or decreasing) depends on both the temperature and the amplitude of the switching pulse at the gate. The isothermal transients are analyzed spectroscopically in a time domain to extract the degree of non-exponentiality and its possible origin in trap kinetics. We propose a phenomenological model in which the exchange of electrons between interfacial ions and traps controls the nature of the drain current transients dictated by the Fermi level position. The origin of interfacial ions is attributed to the essential fabrication step of UV-ozone treatment of the dielectric prior to semiconductor deposition.

  3. Original pedagogues

    DEFF Research Database (Denmark)

    Schmidt, Christina Haandbæk

    Original pedagogues Distention between competences and originality By Christina Haandbæk Schmidt, ph. d. student Aarhus University, Denmark This presentation concerns a Ph.D. project (Sept. 2012 –Sept. 2015) about pedagogues in day care facilities and their struggles to develop and retain...... shall argue that it is necessary for the pedagogues to know how they are constituted by the regimes of power on one side and on the other side are forced to create themselves. This knowledge could transform pedagogues into what I suggest calling ‘original pedagogues’, who have an authentic, ethic...... and professional autonomy in exercising judgment concerning pedagogical situations. To understand how pedagogues can struggle the distention between being competent and being original the project draws on both Michel Foucault and Charles Taylor as two incompatible theories on modern identity. The study...

  4. The Development of Global and Domain Self-Esteem from Ages 10 to 16 for Mexican-Origin Youth

    Science.gov (United States)

    Harris, Michelle A.; Wetzel, Eunike; Robins, Richard W.; Donnellan, M. Brent; Trzesniewski, Kali H.

    2018-01-01

    The current study investigated the development of global and domain (academic, physical, same-sex peer relationship, opposite-sex peer relationship) self-esteem from age 10 to 16 in a sample of Mexican-origin adolescents. Participants' (N = 674) responses on the Self-Description Questionnaire (SDQ; Marsh, 2005) II-S showed moderate rank-order…

  5. Developing powerful tritide technique: Organic and biological molecule labeling

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    Complex hydrides are very important reagents in organic synthesis due to the range of reducing powers and selectivities available from different agents. Unfortunately, the availability of these compounds for radiosynthesis has been extremely limited due to the difficulty of making them with adequate levels of tritium. Investigators at the Lawrence Berkeley Laboratory (LBL) National Tritium Labeling Facility have developed a new addition to the repertoire of the tritium-labeling chemist. The new method allows site-specific incorporation of tritium into organic and biological molecules by efficient reduction processes. Exceptionally reactive and selective reducing agents are prepared and used for labeling in a on-pot process. Three new tritide reagents - supertritide (lithium triethyl borotritide), LiAlT 4 (lithium aluminum tritide), and L-Selectride (sterically hindered lithium tri-sec-butyl borotritide) - have been synthesized at carrier-free levels, and have been demonstrated to be fully reactive. The availability of these versatile and reactive reagents gives the tritium radiochemist great control over chemoselectivity and stereoselectivity. The LBL tritide reagents can drive numerous conventional chemical reactions, and have been used to reduce p-toluene sulfonates, amides, lactones, esters, and aldehydes. These reactions produce good yields and result in products with maximum specific activities. The reagents clearly exhibit superior reactivity and may be used in many more synthetic processes than sodium borohydride, which is the currently used reagent. In addition, tritide reagents such as L-selectride have been shown to give greater control over stereochemistry and selectivity than sodium borohydride

  6. Organization development in a psychiatric hospital: creating desirable changes.

    Science.gov (United States)

    Cope, D; Cox, S

    1980-07-01

    The organization of the way in which hospitals and hospital staff provide a service to patients is obviously of critical importance to their effectiveness, yet it is clear that rigidities and inappropriate and ineffective procedures frequently intrude. It is commonly held that changing hospitals as organizations is difficult to acomplish, and indeed, reported attempts at such change reflect this. The project reported here was a successful attempt at changing a number of different aspects of the culture of a psychiatric hospital which included managerial practices and structure, aspects of patient care, multidisciplinary team work, and staff development. The present paper concentrates on some specific outcomes at ward level. The general pattern for bringing about change involves the collection of (valid) data and then feeding this back to the staff involved so that they can take appropriate action. The data discussed here concerned ward nursing staff's attitude to the 'climate' of the hospital, their job satisfaction and aspects of patient care. This was fed back to nursing, managerial and medical staff, and action plans were agreed to overcome the difficulties highlighted. Outcomes have included the production of ward and unit objectives and changes in treatment programmes and aspects of patient care on the wards.

  7. 14. Policies and Institutions - Nongovernmental organizations: A growing force in the developing world

    International Nuclear Information System (INIS)

    Livernash, R.; Paden, M.

    1992-01-01

    An extraordinarily diverse and growing body of private organizations now dot the world's institutional landscape, working in a variety of areas such as small-scale local development, the conservation of tropical forests, and sustainable agriculture. Working at many levels, through example or advocacy these groups are influencing the direction of environment and development policy around the world. Non-governmental organizations (NGOs) are extraordinarily diverse. This chapter provides a few examples to capture some of that diversity, but focuses mainly on the strengths and weaknesses of NGOs, on the relationship between governments and NGOs, and on some emerging trends. The chapter primarily concerns the newly emerging grassroots and service NGOs in developing countries and those Northern NGOs that work extensively in developing countries. Topics discussed are: origins and regional differences (northern NGOs with a mission in the south, Asia, Latin America, Africa); strengths and weaknesses; key organizational factors (getting started, getting bigger, the impact of leadership, the role of women); government-NGO relations; emerging trends (evolving North-South relations, networks and associations - forging larger alliances, the information explosion global networking, new roles for policy research and legal defense)

  8. Origin of long lifetime of band-edge charge carriers in organic-inorganic lead iodide perovskites.

    Science.gov (United States)

    Chen, Tianran; Chen, Wei-Liang; Foley, Benjamin J; Lee, Jooseop; Ruff, Jacob P C; Ko, J Y Peter; Brown, Craig M; Harriger, Leland W; Zhang, Depei; Park, Changwon; Yoon, Mina; Chang, Yu-Ming; Choi, Joshua J; Lee, Seung-Hun

    2017-07-18

    Long carrier lifetime is what makes hybrid organic-inorganic perovskites high-performance photovoltaic materials. Several microscopic mechanisms behind the unusually long carrier lifetime have been proposed, such as formation of large polarons, Rashba effect, ferroelectric domains, and photon recycling. Here, we show that the screening of band-edge charge carriers by rotation of organic cation molecules can be a major contribution to the prolonged carrier lifetime. Our results reveal that the band-edge carrier lifetime increases when the system enters from a phase with lower rotational entropy to another phase with higher entropy. These results imply that the recombination of the photoexcited electrons and holes is suppressed by the screening, leading to the formation of polarons and thereby extending the lifetime. Thus, searching for organic-inorganic perovskites with high rotational entropy over a wide range of temperature may be a key to achieve superior solar cell performance.

  9. Experimental studies of the mechanisms and the kinetic and thermodynamic aspects of the uranium reduction by sedimentary organic materials from ligneous origin under diagenetic or hydrothermal conditions

    International Nuclear Information System (INIS)

    Nakashima, S.

    1984-01-01

    This research thesis reports experimental studies of fixation and reduction of the uranyl cation by sedimentary organic materials from ligneous origin in order to understand the mechanisms and quantitative aspects of these processes in diagenetic or hydrothermal conditions. Two fixation mechanisms have been identified. Reduction appears to be governed by the oxidation of hydroxyl functions and the dehydrogenation of aliphatic hydro-carbonated entities. A kinetic study of this reduction process is reported, as well as a simulation of these processes by simple organic compounds (alcohols, aliphatic hydrocarbons). The assessment of thermodynamic parameters of the reduction process is discussed, and the obtained thermodynamic data show that almost the totality of uranium present in natural waters precipitates under the form of uraninite in presence of lignite. The extension of the obtained results to all sedimentary organic materials is finally discussed [fr

  10. Glycoconjugates distribution during developing mouse spinal cord motor organizers.

    Science.gov (United States)

    Vojoudi, Elham; Ebrahimi, Vahid; Ebrahimzadeh-Bideskan, Alireza; Fazel, Alireza

    2015-01-01

    The aim of this research was to study the distribution and changes of glycoconjugates particularly their terminal sugars by using lectin histochemistry during mouse spinal cord development. Formalin-fixed sections of mouse embryo (10-16 fetal days) were processed for lectin histochemical method. In this study, two groups of horseradish peroxidase-labeled specific lectins were used: N-acetylgalactosamine, including Dolichos biflorus, Wisteria floribunda agglutinin (WFA), Vicia villosa, Glycine max as well as focuse-binding lectins, including tetragonolobus, Ulex europaeus, and Orange peel fungus (OFA). All sections were counterstained with alcian blue (pH 2.5). Our results showed that only WFA and OFA reacted strongly with the floor plate cells from early to late embryonic period of developing spinal cord. The strongest reactions were related to the 14, 15, and 16 days of tissue sections incubated with OFA and WFA lectins. The present study demonstrated that cellular and molecular differentiation of the spinal cord organizers is a wholly regulated process, and α-L-fucose, α-D-GalNAc, and α/β-D-GalNAc terminal sugars play a significant role during the prenatal spinal cord development.

  11. Positioning for the Development of New Rural Financial Organizations

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Based on regional differences,differences in the content and scale of economic activities,we analyze different levels of rural financial needs in China,using the system analysis method.Different types of financial need subject have characteristics of diversity and hierarchy in terms of financial needs,in need of different credit patterns and credit mechanisms for satisfaction.Based on this,we position the differentiated development of new rural financial organizations as follows:village and town banks should be established in the central and west regions and counties with the proportion of primary industry higher than the national average,to actively innovate upon loan types,support maintenance-oriented farmers, market-oriented farmers and small and medium-sized agriculture-related enterprises;loan companies and small loan companies can be established in the regions with the potential for development,lacking collaboration between economy and finance,to constantly explore the loan types and innovate upon the loan patterns for self-employed households,micro-enterprises and farmers;it is appropriate to establish rural credit union in the poverty-stricken areas with sluggish economic development and relatively isolated remote areas,to provide services for farmers and micro-enterprises, especially impoverished farmers,provide the business such as deposits,loans,and settlement for members,actively carry out business consulting services for members’poverty alleviation and income increase.

  12. Development and Functional Organization of the Cranial Nerves in Lampreys.

    Science.gov (United States)

    Pombal, Manuel A; Megías, Manuel

    2018-04-16

    Lampreys, together with hagfishes, are the only extant representatives of the oldest branch of vertebrates, the agnathans, which are the sister group of gnathostomes; therefore, studies on these animals are of great evolutionary significance. Lampreys exhibit a particular life cycle with remarkable changes in their behavior, concomitant, in part, with important modifications in the head and its musculature, which might influence the development of the cranial nerves. In this context, some cranial nerves such as the optic nerve and the ocular motor nerves, which develop slowly during an extremely long larval period lasting more than five years, have been more thoroughly investigated; however, much less experimental information is available about others, such as the facial or the hypoglossal nerves. In addition, the possible existence of a "true" accessory nerve in these animals is still a matter of conjecture. Although growing in last decades, investigations on the physiology of the lamprey cranial nerves is scanty. This review focuses on past and recent findings that have contributed to characterize the anatomical organization of the cranial nerves in lampreys, including their components and nuclei, and their relations in the brain; in addition, comments on their development and functional role are also included. Anat Rec, 2018. © 2018 Wiley Periodicals, Inc. © 2018 Wiley Periodicals, Inc.

  13. Pancreatic morphogenesis and extracellular matrix organization during rat development.

    Science.gov (United States)

    Hisaoka, M; Haratake, J; Hashimoto, H

    1993-07-01

    We investigated the rat pancreatic morphology at various developmental stages ranging from 12 days of gestation to the neonatal stage, with special emphasis on alterations in extracellular matrix organization in vivo. The rat pancreatic development in utero could be divided into four representative stages as follows: (1) initial epithelial buds (12 days of gestation), (2) elongated and branching epithelium (13-14 days), (3) tubular structure (15-16 days), and (4) acinar structure (17 days or more). Ultrastructurally, the fetal and neonatal pancreata were almost constantly encompassed by continuous basal lamina, except for the earliest stage, in which minute disruptions of basal lamina were observed. Through the disruption, the direct epithelial-mesenchymal contact was formed between an endocrine cell and an adjacent mesenchymal cell, which implied epithelial-mesenchymal interactions in processes of endocrine cell differentiation. Collagen fibrils were frequently accumulated at the cleft (branchpoint) of the branching epithelium during the second and third stages mentioned above. Immunohistochemically, fibronectin and collagen type-I were localized particularly beside the neck (narrow part) or cleft of the pancreatic epithelium at these stages, although continuous linear localization of these matrices was noted around the initial pancreatic bud. This was in contrast to invariable linear localization of laminin and collagen type-IV at the epithelial/mesenchymal interface throughout the pancreatic development. Diffuse fibrillar localization of fibronectin and collagen type-I in the mesenchyme was pronounced at the later stages and after birth. Collagen type-III was only focally detectable around the pancreatic epithelium from the second stage, and its distinct localization was noted in the interlobular connective tissue after birth. Thus, chronological changes in extracellular matrix organization seemed to be closely related to morphogenetic processes of the rat

  14. [Necrotizing cervico-facial cellulitis of dental origin in a developing country].

    Science.gov (United States)

    Togo, S; Ouattara, M A; Saye, J; Sangaré, I; Touré, M; Maiga, I; Dakouo, D J; Xing, L; Guo, L; Zhou, A J; Koumaré, S; Koita, A K; Sanogo, Z Z; Yéna, S

    2017-09-01

    Necrotizing cellulitis of dental origin is a serious disease and requires prompt and effective management to avoid adverse outcomes. The purpose of this work is to describe the diagnostic and therapeutic difficulties encountered in this condition. This was a prospective study in the thoracic surgery department of Mali Hospital from January 2011 to February 2015. We collected consecutively 19 cases of complicating cervico-facial cellulitis of dental origin. The anatomical and clinical aspects, therapeutic modalities and difficulties are described. Dental pain and fever were the predominant symptoms followed by cervical edema. Chest CT-scan was the basis for the diagnosis in all cases. Cervicotomy with debridement was the most performed surgical procedure. Pleural drainage was performed in 6 cases. Three patients (15.8%) died. Necrotizing cellulitis of dental origin is a serious disease with high morbidity and mortality. The key radiological examination is the thoracic CT-scan. Early medico-surgical management by emergency care, tailored antibiotic therapy, removal of necrotizing tissues and drainage of collections are required to deliver a good outcome. Copyright © 2016 SPLF. Published by Elsevier Masson SAS. All rights reserved.

  15. Elemental and isotopic characterization of organic particles in carbonaceous chondrites by NanoSIMS imaging: assessment on the origin, accretion and preservation of organic matter in chondrites

    Science.gov (United States)

    Remusat, L.; Guan, Y.; Eiler, J. M.

    2009-12-01

    Chondrites accreted primitive components, including organic compounds sampled from the proto-solar nebula. However, the molecular and isotopic fingerprints of organic matter extracted from chondrites are also potentially influenced by complex evolution on the parent bodies. We have performed NanoSIMS in situ characterisation of organic matter in the matrices of carbonaceous chondrites Orgueil (CI), Murchison (CM), Tagish Lake (C2), Renazzo (CR) and Allende (CV) with a spatial resolution of ~200 nm; we could also constrains textural relationships between organic constituents and other phases. Those meteorites have undergone a diverse set of parent body processes. I.e., CI, C2 and CM meteorites have undergone aqueous alteration, and the CV’s are thermally metamorphosed. The CR’s are inferred to be the least altered class of chondrites. Despite these differences in parent body modification, the distributions of organic carbon in these meteorites is similar: in all cases it can be found as micron-size, randomly distributed organic particles that are surrounded by the clay minerals that dominate the matrix material, but are not specifically associated with sulfides, sulfates or oxides. In addition, there is a “diffuse” fraction of organic carbon intimately associated with the clay-rich matrix. We hypothesize that the C particles we identify are hosts of insoluble organic matter that co-accreted with other primitive constituents of these materials, whereas the diffuse C fraction is the soluble component (i.e., soluble in laboratory organic and aqueous solvents). Our analytical technique lacks the spatial resolution required to analyze the diffuse organic matter without contamination by associated clays. But we are able to analyze the compositions of the interiors of relatively large C-rich particles (>500 nm) without such contamination. Some fraction of the C-rich particles in all of the examined meteorites but Allende exhibit a very high enrichment in deuterium

  16. Organic geochemistry of deep ground waters from the Palo Duro Basin, Texas: implications for radionuclide complexation, ground-water origin, and petroleum exploration

    International Nuclear Information System (INIS)

    Means, J.L.; Hubbard, N.J.

    1985-05-01

    This report describes the organic geochemistry of 11 ground-water samples from the Palo Duro Basin, Texas and discusses the implications of their organic geochemical compositions in terms of radionuclide complexation, ground-water origin, and the petroleum potential of two candidate repository sites in Deaf Smith and Swisher Counties. Short-chain aliphatic acid anions are the principal organic constituents present. Stability constant data and simple chemical equilibria calculations suggest that short-chain aliphatic acids are relatively weak complexing agents. The extent of complexation of a typical actinide by selected inorganic ligands present in these brines is expected to far outweigh actinide complexation by the aliphatic acid anions. Various lines of evidence suggest that some portion of the bromide concentrations in the brines is derived from the same source as the short-chain aliphatic acid anions. When the postulated organic components are subtracted from total bromide concentrations, the origins of the Palo Duro brines, based on chloride versus bromide relationships, appear largely consistent with origins based on isotopic evidence. The short-chain aliphatic acid anion content of the Palo Duro brines is postulated to have been much greater in the geologic past. Aliphatic acid anions are but one of numerous petroleum proximity indicators, which consistently suggest a greater petroleum exploration potential for the area surrounding the Swisher County site than the region encompassing the candidate site in Deaf Smith County. Short-chain aliphatic acid anions appear to provide a useful petroleum exploration tool as long as the complex reactions that may dimish their concentrations in ground water are recognized. 71 refs., 10 figs., 10 tabs

  17. Nepheloid Layers: Origin and Development In A Narrow Continental Shelf (nw Portugal)

    Science.gov (United States)

    Oliveira, A.; Vitorino, J.; Rodrigues, A.; Jouanneau, J. M.; Weber, O.; Dias, J. A.

    A general hydrographic, nephelometric and sedimentological surveying of the NW Portuguese continental shelf and slope was undertaken, under winter and spring con- ditions in order to elaborate a conceptual model of suspended sediments (nepheloid layer) dynamics. Two major situations were found: 1) Spring/Summer - with northerly winds (upwelling) and low energetic wave regime that favour the deposition of sedi- ments. The northerly winds promote offshore transport in the surface nepheloid layer (SNL) and the establishment of a seasonal thermocline allow the expansion of the SNL to the west. The SNL can reach or even cross the shelf-break (50 km from coastline). Particulate organic carbon (POC) content in this layer highlights the higher contribution of biogenic particles (average concentration of 22%); 2) Winter, with southerly winds (downwelling) and high energetic wave regime that favour mid- shelf sediments resuspension and offshore transport in the bottom nepheloid layer (BNL). In the shelf-break the BNL detached to form intermediate nepheloid layers (INL). The SNL is restricted to the inner shelf. The effect of southerly winds gener- ates shoreward Ekman transport and detains the offshore westward extension of this layer even during high river run-off periods. The POC content indicates a dominance of litogenic particles in suspension (average concentration of 8%). Over the mid- and inner-shelf the dominant resuspension mechanism is associated with surface waves (Vitorino et al., 2002). Estimates based on wave measurements at mid-shelf (86m depth) suggested that, in winter, the wave shear velocity frequently exceeds 1 cm/s, assumed as the critical shear velocity for the resuspension of the fine grained sedi- ments (34m) of the bottom cover. Storm events, such as the one observed in November 1996 easily increase the wave shear velocities over 3 cm/s, leading to the increase of the BNL thickness (20-30m) (Vitorino et al., 2002; Oliveira et al., 2002). Low

  18. Toward Molecular Magnets of Organic Origin via Anion-π Interaction Involving m-Aminyl Diradical: A Theoretical Study

    DEFF Research Database (Denmark)

    Bhattacharya, Debojit; Shil, Suranjan; Misra, Anirban

    2016-01-01

    Here we study a set of novel magnetic organic molecular species with different halide ions (fluoride, chloride, bromide) absorbed ∼2 Å above or below the center of an aromatic π-ring in an m-aminyl diradical. Focus is on the nature of anion-π interaction and its impact on magnetic properties, spe...

  19. Origin of organic sulphur compounds and sulphur-containing high molecular weight substances in sediments and immature crude oils

    NARCIS (Netherlands)

    Sinninghe Damsté, J.S.; Rijpstra, W.I.C.; Leeuw, J.W. de; Schenck, P.A.

    1988-01-01

    The distribution patterns of Organic Sulphur Compounds (OSC), occurring in certain sediments and immature crude oils, were compared with those of the corresponding hydrocarbons. Because of the complexity of the OSC mixtures, they were desulphurized to hydrocarbons (n-alkanes, isoprenoid alkanes,

  20. Conference on chemical evolution and the origin of life: Self-organization of the macromolecules of life

    International Nuclear Information System (INIS)

    1993-10-01

    The formation of biomolecules was a necessary step in the evolution of life on earth. This interdisciplinary conference emphasized the role of replication in processes of self-organization of biological macromolecules. The present document contains abstracts of the 26 contributions to the conference on chemical evolution. The individual contributions have been indexed separately for the database

  1. Revealing Buried Interfaces to Understand the Origins of Threshold Voltage Shifts in Organic Field-Effect Transistors

    NARCIS (Netherlands)

    Mathijssen, Simon G. J.; Spijkman, Mark-Jan; Andringa, Anne-Marije; van Hal, Paul A.; McCulloch, Iain; Kemerink, Martijn; Janssen, Rene A. J.; de Leeuw, Dago M.

    2010-01-01

    The semiconductor of an organic field-effect transistor is stripped with adhesive tape, yielding an exposed gate dielectric, accessible for various characterization techniques. By using scanning Kelvin probe microscopy we reveal that trapped charges after gate bias stress are located at the gate

  2. Nature, origin and average age of estuarine ultrafiltered dissolved organic matter as determined by molecular and carbon isotope characterization

    NARCIS (Netherlands)

    van Heemst, JDH; Megens, L; Hatcher, PG; de Leeuw, JW

    2000-01-01

    The Ems-Dollart estuary (on the border of the Netherlands and Germany) was chosen for a pilot study to characterize ultrafiltered dissolved organic matter (UDOM) in estuarine systems. UDOM samples were taken from four locations with salinities varying from 0.43 to 20 parts per thousand. The UDOM in

  3. Advance Organizers: Their Construction and Use in Instructional Development.

    Science.gov (United States)

    Newell, John

    This chapter presents a review of the latest research on advance organizers, and provides instructions for constructing and using them. The theoretical background of the advance organizers research is presented, beginning with the work of Ausubel, and this work is related to the writings of Piaget. An outline of advance organizer research is then…

  4. An appraisal of training and development in organizations in Nigeria ...

    African Journals Online (AJOL)

    The leading expectation of an organization and its employees is growth. When there is growth, the organization will experience stability, expansion, and good profit margin. The employees also stand to attend to their personal needs and have some level of satisfaction. Growth in an organization is manifested in having large ...

  5. Development, organization, and remodeling of phoronid muscles from embryo to metamorphosis (Lophotrochozoa: Phoronida).

    Science.gov (United States)

    Temereva, Elena N; Tsitrin, Eugeni B

    2013-04-24

    The phoronid larva, which is called the actinotrocha, is one of the most remarkable planktotrophic larval types among marine invertebrates. Actinotrochs live in plankton for relatively long periods and undergo catastrophic metamorphosis, in which some parts of the larval body are consumed by the juvenile. The development and organization of the muscular system has never been described in detail for actinotrochs and for other stages in the phoronid life cycle. In Phoronopsis harmeri, muscular elements of the preoral lobe and the collar originate in the mid-gastrula stage from mesodermal cells, which have immigrated from the anterior wall of the archenteron. Muscles of the trunk originate from posterior mesoderm together with the trunk coelom. The organization of the muscular system in phoronid larvae of different species is very complex and consists of 14 groups of muscles. The telotroch constrictor, which holds the telotroch in the larval body during metamorphosis, is described for the first time. This unusual muscle is formed by apical myofilaments of the epidermal cells. Most larval muscles are formed by cells with cross-striated organization of myofibrils. During metamorphosis, most elements of the larval muscular system degenerate, but some of them remain and are integrated into the juvenile musculature. Early steps of phoronid myogenesis reflect the peculiarities of the actinotroch larva: the muscle of the preoral lobe is the first muscle to appear, and it is important for food capture. The larval muscular system is organized in differently in different phoronid larvae, but always exhibits a complexity that probably results from the long pelagic life, planktotrophy, and catastrophic metamorphosis. Degeneration of the larval muscular system during phoronid metamorphosis occurs in two ways, i.e., by complete or by incomplete destruction of larval muscular elements. The organization and remodeling of the muscular system in phoronids exhibits the combination of

  6. Development, organization, and remodeling of phoronid muscles from embryo to metamorphosis (Lophotrochozoa: Phoronida)

    Science.gov (United States)

    2013-01-01

    Background The phoronid larva, which is called the actinotrocha, is one of the most remarkable planktotrophic larval types among marine invertebrates. Actinotrochs live in plankton for relatively long periods and undergo catastrophic metamorphosis, in which some parts of the larval body are consumed by the juvenile. The development and organization of the muscular system has never been described in detail for actinotrochs and for other stages in the phoronid life cycle. Results In Phoronopsis harmeri, muscular elements of the preoral lobe and the collar originate in the mid-gastrula stage from mesodermal cells, which have immigrated from the anterior wall of the archenteron. Muscles of the trunk originate from posterior mesoderm together with the trunk coelom. The organization of the muscular system in phoronid larvae of different species is very complex and consists of 14 groups of muscles. The telotroch constrictor, which holds the telotroch in the larval body during metamorphosis, is described for the first time. This unusual muscle is formed by apical myofilaments of the epidermal cells. Most larval muscles are formed by cells with cross-striated organization of myofibrils. During metamorphosis, most elements of the larval muscular system degenerate, but some of them remain and are integrated into the juvenile musculature. Conclusion Early steps of phoronid myogenesis reflect the peculiarities of the actinotroch larva: the muscle of the preoral lobe is the first muscle to appear, and it is important for food capture. The larval muscular system is organized in differently in different phoronid larvae, but always exhibits a complexity that probably results from the long pelagic life, planktotrophy, and catastrophic metamorphosis. Degeneration of the larval muscular system during phoronid metamorphosis occurs in two ways, i.e., by complete or by incomplete destruction of larval muscular elements. The organization and remodeling of the muscular system in phoronids

  7. Developing SoTL through Organized Scholarship Institutes

    Directory of Open Access Journals (Sweden)

    Elizabeth Marquis

    2015-12-01

    Full Text Available The need to further integrate SoTL into college and university cultures has been discussed relatively frequently in recent teaching and learning literature. While a number of useful strategies to assist in this task have been advanced, one especially promising suggestion is the development of organized, institutionally-recognized scholarship institutes. Centres or units of this sort have been created at higher education institutions in a number of countries, but little published information currently exists about the design of these institutes or the experiences of individuals affiliated with them. To that end, the present study sought to examine the perceived benefits, challenges and design features of teaching and learning scholarship institutes at research-intensive universities worldwide. A website scan and a survey of individuals affiliated with these units were used to collect qualitative and quantitative data of relevance to the research questions. Based on the findings, and on ideas from the existing research institute and scholarship of teaching and learning literatures, a series of recommendations for individuals and campuses interested in developing effective SoTL institutes are provided.

  8. OECD (Organization of Economic Cooperation and Development) oil demand

    International Nuclear Information System (INIS)

    Huntington, H.G.

    1993-01-01

    Econometric response surfaces for nine different world oil models are estimated for aggregate oil demand with in the developed countries of the Organization of Economic Cooperation and Development (OECD). The estimates are based upon scenario results reported for the 1989-2010 period in a recent model comparison study. The response surface approach provides a parsimonious summary of model responses. It enables one to estimate long-run price elasticities directly rather than to infer such responses from 20-year cross-scenario results. It also shows more directly the significant effect of initial demand conditions (in 1988) on future oil demand growth. Due to the dynamic nature of the oil demand response, past prices exert a strongly positive effect on future oil demands in some models, but little or even negative effect in other models. On the basis of this finding, we urge demand modellers to be much more explicit about what their systems reveal about the extent of disequilibrium embedded in their model's starting oil demand conditions. (author)

  9. Development of Biofertilizer from Sugar Industry Organic Waste

    International Nuclear Information System (INIS)

    Abbas, G.; Hussain, A.; Abbas, G.; Ali, M.

    2013-01-01

    The present study was conducted for development of biofertilizer from soil rhizospheric microorganisms in organic waste as carrier material and its application in agriculture development. The bacteria were isolated from rice rhizosphere from NIBGE field experiments. Some of the isolates of sunflower were collected from BIRCEN culture collection. The morphological characteristics of the isolates were studied. The bacteria were also characterized for their biochemical characteristics regarding nitrogen fixation, phosphate solubilization and indole acetic acid (IAA) production. These isolates were used for Biofertilizer production. Press mud from sugar industry was used as a carrier material to carry these inoculums. The carrier material was ground to a fine powder of 100 mesh size and weighted quantity of mud was packed in polythene bags. Then appropriate amount of approximately 5% the inoculum was injected to the packed polythene bags through injectors. The inoculated polythene bags were mixed by mixer and were sealed through electric sealer. The prepared polythene bags of biofertilizer were stored at cool and dry place away from sunlight, as these inoculum polythene bags may be damaged at higher temperature. (author)

  10. Relationships between Organizations and Publics: Development of a Multi-Dimensional Organization-Public Relationship Scale.

    Science.gov (United States)

    Bruning, Stephen D.; Ledingham, John A.

    1999-01-01

    Attempts to design a multiple-item, multiple-dimension organization/public relationship scale. Finds that organizations and key publics have three types of relationships: professional, personal, and community. Provides an instrument that can be used to measure the influence that perceptions of the organization/public relationship have on consumer…

  11. How Does the Modular Organization of Entorhinal Grid Cells Develop?

    Directory of Open Access Journals (Sweden)

    Stephen eGrossberg

    2014-06-01

    Full Text Available The entorhinal-hippocampal system plays a crucial role in spatial cognition and navigation. Since the discovery of grid cells in layer II of medial entorhinal cortex (MEC, several types of models have been proposed to explain their development and operation; namely, continuous attractor network models, oscillatory interference models, and self-organizing map (SOM models. Recent experiments revealing the in vivo intracellular signatures of grid cells (Domnisoru et al., 2013; Schmidt-Heiber & Hausser, 2013, the primarily inhibitory recurrent connectivity of grid cells (Couey et al., 2013; Pastoll et al., 2013, and the topographic organization of grid cells within anatomically overlapping modules of multiple spatial scales along the dorsoventral axis of MEC (Stensola et al., 2012 provide strong constraints and challenges to existing grid cell models. This article provides a computational explanation for how MEC cells can emerge through learning with grid cell properties in modular structures. Within this SOM model, grid cells with different rates of temporal integration learn modular properties with different spatial scales. Model grid cells learn in response to inputs from multiple scales of directionally-selective stripe cells (Krupic et al., 2012; Mhatre et al., 2012 that perform path integration of the linear velocities that are experienced during navigation. Slower rates of grid cell temporal integration support learned associations with stripe cells of larger scales. The explanatory and predictive capabilities of the three types of grid cell models are comparatively analyzed in light of recent data to illustrate how the SOM model overcomes problems that other types of models have not yet handled.

  12. Two year-long continuous monitoring of PM1 aerosol chemical composition at the Cyprus Atmospheric Observatory. Source apportionment of the Organic content and geographic origins.

    Science.gov (United States)

    Stavroulas, Iasonas; Pikridas, Michael; Oikonomou, Kostantina; Vasiliadou, Emily; Savvides, Chrysanthos; Vrekoussis, Mihalis; Mihalopoulos, Nikolaos; Gros, Valerie; Sciare, Jean

    2017-04-01

    Particulate matter with diameter smaller than 1{μ}m (PM1) induces direct and indirect effects on local and regional pollution, global climate and health. As of the beginning of 2015, the chemical composition of submicron aerosols, is continuously being monitored at the newly established Cyprus Atmospheric Observatory (CAO, http://www.cyi.ac.cy/index.php/cao.html), a national facility of the ACTRIS Research Infrastructure operated by The Cyprus Institute. Cyprus, an island located in the Eastern Mediterranean Middle East region and influenced by diverse air masses throughout the year, is ideal for monitoring photochemically aged aerosols and gaseous pollutants of both natural and anthropogenic origin. Furthermore this is a unique dataset for this area in such proximity to the Middle East, a poorly documented area in terms of atmospheric aerosol observations. An Aerodyne Quadrupole Aerosol Chemical Speciation Monitor (Q-ACSM) is currently deployed at the CAO premises (35.04N - 33.06E) situated at the rural area of Agia Marina Xyliatou on the foothill of mount Troodos at an elevation of 532m above sea level (asl). The ACSM delivers chemical composition of the major non-refractory aerosol (PM1) chemical constituents (organics, sulfate, nitrate, ammonium, chloride) with an effective (close to 100{%}) collection efficiency for particles in the diameter range of 65-700 nm at a 30 minute temporal resolution. Black Carbon (BC) was also monitored using both Magee Scientific AE-31 and AE-33 aethalometers. Quality control of the PM chemical dataset was conducted by comparison with chemical analysis performed on collocated 24-h filter samples (PM1) and comparison with 1-h PM2.5 derived from a Thermo Scientific TEOM (1400a) Monitor. Positive Matrix Factorization (PMF) was conducted and different organic aerosol factors were distinguished using the Igor based SoFi toolkit utilizing the ME-2 multilinear engine. Air mass origin was investigated for each measurement day using the

  13. Changes in lymphocytes size under chronic exposure of the organism to factors of radiation and chemical origin

    International Nuclear Information System (INIS)

    Ivanov, V.V.

    1990-01-01

    Results of the analysis of changes in peripheral blood lymphocytes size under chronic exposure to external gamma radiation and pesticide chlorofoz in combination and separately are presented. It has been found out that under exposure of animals to radiation or the pesticide it is small and big lymphocytes respectively which most significantly suffer quantitatively. Under the joint radiational-chemical exposure of the organism the number of both types of cells is reduced simultaneously

  14. First Detection of Water Ice and Organics on an Asteroid: A Possible Link to the Origin of Earth's Water

    Science.gov (United States)

    Hargrove, Kelsey D.; Campins, H.; Pinilla-Alonso, N.; Howell, E. S.; Kelley, M. S.; Licandro, J.; Mothédiniz, T.; Fernández, Y.; Ziffer, J.

    2010-05-01

    We report the detection of water ice and organics on the surface of asteroid 24 Themis. Our rotationally-resolved infrared (2-4 µm) spectra of this asteroid indicate that the ice and organics are widespread on its surface. The spectral difference with other asteroids observed in the same manner, makes 24 Themis unique so far. Our identification of water ice and organic compounds on this asteroid agrees with independent results (Rivkin and Emery 2010). At first glance, the presence of any surface ice on 24 Themis, particularly over a significant fraction of its surface, is puzzling because of the instability for exposed water ice at Themis's heliocentric distance ( 3.2 AU). Nevertheless, there are several possible sources for this unstable ice and identifying them is likely to be diagnostic of other processes on primitive asteroids. The presence of water ice on 24 Themis supports the idea that ice sublimation drives the cometary activity in two small members of the Themis dynamical family, labeled "Main Belt comets” by Hsieh and Jewitt (2006). It also helps to address other relevant questions, such as, how abundant is water ice in the outer asteroid belt and where was the "snow” line when the solar system formed? The answers to these questions could transform current views of primitive asteroids, delivery of water and organic molecules to Earth, and models of Solar System formation. This research was published in the April 29, 2010 issue of the journal Nature. Hargrove and Campins are visiting astronomers at the Infrared Telescope Facility (IRTF), which is operated by the University of Hawaii under Cooperative Agreement no. NCC 5-538 with the National Aeronautics and Space Administration

  15. Reclamation of cadmium-contaminated soil using dissolved organic matter solution originating from wine-processing waste sludge

    International Nuclear Information System (INIS)

    Liu, Cheng-Chung; Chen, Guan-Bu

    2013-01-01

    Highlights: ► Increases in acidity, washing frequency, and operational temperature enhance the Cd removal. ► Approximately 80% of Cd can be removed from the soil by dissolved organic matter (DOM) washing. ► The DOM washing can moderate the loss of soil fertility. ► The DOM washing will have a great improvement if we employ NaOH, KOH, Ca(OH) 2 , and Mg(OH) 2 to prepare the DOM solution together. -- Abstract: Soil washing using an acid solution is a common practice for removing heavy metals from contaminated soil in Taiwan. However, serious loss of nutrients from soil is a major drawback of the washing. Distillery sludge can be used to prepare a dissolved organic matter (DOM) solution by extracting its organic constituents with alkaline solutions. This study employed DOM solutions to remediate Cd-contaminated soil (with concentrations up to 21.5 mg kg −1 ) and determine the factors affecting removal of Cd, such as pH, initial concentration of DOM solution, temperature, and washing frequency. When washing with pH 3.0 and 1250 mg L −1 DOM solution, about 80% and 81% of Cd were removed from the topsoil at 27 °C and subsoil at 40 °C, respectively. To summarize the changes in fertility during DOM washing with various pH solutions: the increase in organic matter content ranged from 7.7% to 23.7%; cation exchange capacity (CEC) ranged from 4.6% to 13.9%; available ammonium (N-NH 4 ) content ranged from 39.4% to 2175%; and available phosphorus content ranged from 34.5% to 182%. Exchangeable K, Ca, and Mg remained in the topsoil after DOM washing, with concentrations of 1.1, 2.4, and 1.5 times higher than those treated with HCl solution at the same pH, respectively

  16. Natural origin arsenic in aquatic organisms from a deep oligotrophic lake under the influence of volcanic eruptions.

    Science.gov (United States)

    Juncos, Romina; Arcagni, Marina; Rizzo, Andrea; Campbell, Linda; Arribére, María; Guevara, Sergio Ribeiro

    2016-02-01

    Volcanic eruptions are recognized sources of toxic elements to freshwater, including arsenic (As). In order to study the short term changes in the bioaccumulation of naturally occurring As by aquatic organisms in Lake Nahuel Huapi (Argentina), located close to the Puyehue-Cordón Caulle volcanic complex (PCCVC), we described As concentrations at different trophic levels and food web transfer patterns in three sites of the lake prior to the last PCCVC eruption (June 2011), and compared As concentrations in biota before and after the eruption. The highest As concentrations and greater variations both between sites and position in the water column, were observed in phytoplankton (3.9-64.8 µg g(-1) dry weight, DW) and small zooplankton (4.3-22.3 µg g(-1) DW). The pattern of As accumulation in aquatic organisms (whole body or muscle) was: primary producers (phytoplankton) > scrapper mollusks (9.3-15.3 µg g(-1) DW) > filter feeding mollusks (5.4-15.6 µg g(-1) DW) > omnivorous invertebrates (0.4-9.2 µg g(-1) DW) > zooplankton (1.2-3.5 µg g(-1) DW) > fish (0.2-1.9 µg g(-1) DW). We observed As biodilution in the whole food web, and in salmonids food chains, feeding on fish prey; but biomagnification in the food chain of creole perch, feeding on benthic crayfish. The impact of the 2011 PCCVC eruption on the As levels of biota was more evident in pelagic-associated organisms (zooplankton and planktivorous fish), but only in the short term, suggesting a brief high bioavailability of As in water after ash deposition. In benthic organisms As variations likely responded to shift in diet due to coverage of the littoral zone with ashes. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. ORIGINAL ARTICLE

    African Journals Online (AJOL)

    User

    source of blood supply whilst in developed countries VNRDs are the major source. This study de- termined and ... UDS Publishers Limited All Right Reserved 2026-6294. ORIGINAL ..... ferral rate of females in comparison to males as pre- .... nors at blood bank of a medical college,. Australia. Med J Armed Forces 61: 131- 4.

  18. Grain dust originating from organic and conventional farming as a potential source of biological agents causing respiratory diseases in farmers.

    Science.gov (United States)

    Zukiewicz-Sobczak, Wioletta A; Cholewa, Grażyna; Krasowska, Ewelina; Chmielewska-Badora, Jolanta; Zwoliński, Jacek; Sobczak, Paweł

    2013-12-01

    Agricultural producers are exposed to a number of different health risks associated with their work environment. The objective of the study was to assess the degree of colonization by fungi in terms of quantity and in terms of variety of species the samples taken from the settled dust from combine threshing of rye cultivation from organic and conventional farms in the Province of Lublin. This paper is a preliminary quantitative assessment of the species of fungi colonizing the samples of settled dust collected during combine threshing from organic and conventional farms in the Province of Lublin. One of the stages of the project was the classification of biosafety BSL (biosafety level) of selected isolates and API ZYM tests to evaluate the potential ability of isolates to cause adverse health effects. To determine the concentration and composition of fungi in collected samples plate dilution method was used with two media: Malt Agar and Potato Dextrose Agar. MOST COMMONLY ISOLATED FUNGI IN SETTLED DUST SAMPLES COLLECTED DURING COMBINE THRESHING FROM ORGANIC FARMS, ON PDA MEDIUM WERE: Alternaria alternata and Aureobasidium pullulans. Cultures on MA medium were dominated by Alternaria alternata, Mycelia sterilia and Fusarium poae. In samples of dust from conventional crops, the predominant species was Alternaria alternata on PDA medium and on MA medium. The obtained results show a potential risk of people involved in agricultural work.

  19. Reclamation of cadmium-contaminated soil using dissolved organic matter solution originating from wine-processing waste sludge.

    Science.gov (United States)

    Liu, Cheng-Chung; Chen, Guan-Bu

    2013-01-15

    Soil washing using an acid solution is a common practice for removing heavy metals from contaminated soil in Taiwan. However, serious loss of nutrients from soil is a major drawback of the washing. Distillery sludge can be used to prepare a dissolved organic matter (DOM) solution by extracting its organic constituents with alkaline solutions. This study employed DOM solutions to remediate Cd-contaminated soil (with concentrations up to 21.5 mg kg(-1)) and determine the factors affecting removal of Cd, such as pH, initial concentration of DOM solution, temperature, and washing frequency. When washing with pH 3.0 and 1250 mg L(-1) DOM solution, about 80% and 81% of Cd were removed from the topsoil at 27 °C and subsoil at 40 °C, respectively. To summarize the changes in fertility during DOM washing with various pH solutions: the increase in organic matter content ranged from 7.7% to 23.7%; cation exchange capacity (CEC) ranged from 4.6% to 13.9%; available ammonium (NNH(4)) content ranged from 39.4% to 2175%; and available phosphorus content ranged from 34.5% to 182%. Exchangeable K, Ca, and Mg remained in the topsoil after DOM washing, with concentrations of 1.1, 2.4, and 1.5 times higher than those treated with HCl solution at the same pH, respectively. Copyright © 2012 Elsevier B.V. All rights reserved.

  20. From 'circumstances' to 'environment': Herbert Spencer and the origins of the idea of organism-environment interaction.

    Science.gov (United States)

    Pearce, Trevor

    2010-09-01

    The word 'environment' has a history. Before the mid-nineteenth century, the idea of a singular, abstract entity--the organism--interacting with another singular, abstract entity--the environment--was virtually unknown. In this paper I trace how the idea of a plurality of external conditions or circumstances was replaced by the idea of a singular environment. The central figure behind this shift, at least in Anglo-American intellectual life, was the philosopher Herbert Spencer. I examine Spencer's work from 1840 to 1855, demonstrating that he was exposed to a variety of discussions of the 'force of circumstances' in this period, and was decisively influenced by the ideas of Auguste Comte in the years preceding the publication of Principles of psychology (1855). It is this latter work that popularized the word 'environment' and the corresponding idea of organism--environment interaction--an idea with important metaphysical and methodological implications. Spencer introduced into the English-speaking world one of our most enduring dichotomies: organism and environment. Copyright © 2010 Elsevier Ltd. All rights reserved.

  1. Organic geochemistry investigations of crude oils from Bayoot oilfield in the Masila Basin, east Yemen and their implication for origin of organic matter and source-related type

    Directory of Open Access Journals (Sweden)

    Mohammed Hail Hakimi

    2018-03-01

    Full Text Available Thirteen crude oil samples from fractured basement reservoir rocks in the Bayoot oilfield, Masila Basin were studied to describe oil characteristics and to provide information on the source of organic matter input and the genetic link between oils and their potential source rock in the basin. The bulk geochemical results of whole oil and gasoline hydrocarbons indicate that the Bayoot oils are normal crude oil, with high hydrocarbons of more than 60%. The hydrocarbons are dominated by normal, branched and cyclic alkanes a substantial of the light aromatic compounds, suggesting aliphatic oil-prone kerogen. The high abundant of normal, branched and cyclic alkanes also indicate that the Bayoot oils are not biodegradation oils.The biomarker distributions of isoprenoid, hopane, aromatic and sterane and their cross and triangular plots suggest that the Bayoot oils are grouped into one genetic family and were generated from marine clay-rich source rock that received mixed organic matter and deposited under suboxic conditions. The biomarker distributions of the Bayoot oils are consistent with those of the Late Jurassic Madbi source rock in the basin. Biomarker maturity and oil compositions data also indicate that the Bayoot oils were generated from mature source rock with peak oil-window maturity. Keywords: Crude oil, Basement reservoir rocks, Biomarker, Organic source input, Bayoot oilfield, Masila Basin

  2. Feather development genes and associated regulatory innovation predate the origin of Dinosauria.

    Science.gov (United States)

    Lowe, Craig B; Clarke, Julia A; Baker, Allan J; Haussler, David; Edwards, Scott V

    2015-01-01

    The evolution of avian feathers has recently been illuminated by fossils and the identification of genes involved in feather patterning and morphogenesis. However, molecular studies have focused mainly on protein-coding genes. Using comparative genomics and more than 600,000 conserved regulatory elements, we show that patterns of genome evolution in the vicinity of feather genes are consistent with a major role for regulatory innovation in the evolution of feathers. Rates of innovation at feather regulatory elements exhibit an extended period of innovation with peaks in the ancestors of amniotes and archosaurs. We estimate that 86% of such regulatory elements and 100% of the nonkeratin feather gene set were present prior to the origin of Dinosauria. On the branch leading to modern birds, we detect a strong signal of regulatory innovation near insulin-like growth factor binding protein (IGFBP) 2 and IGFBP5, which have roles in body size reduction, and may represent a genomic signature for the miniaturization of dinosaurian body size preceding the origin of flight. © The Author 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  3. Local self-organization of population and its role in the development of the civil society in Ukraine

    Directory of Open Access Journals (Sweden)

    V. P. Berezinskiy

    2017-07-01

    It has been shown that in general the bodies of self-organization of population are focused on the protection of social, eco-nomic and cultural issues, such as the organization and activities of local self-performed in compliance with law; transparency; voluntarily taking on certain powers of the respective local council; territoriality; election; accountability and responsibility to the respective councils; accountability and responsibility to the residents who have chosen community organizations; financial and institutional independence. It has been proven that the local self-organization of population in Ukraine plays an important role in the development of civil society, reflects the level of democratization at the local level and in the whole state. The experience of democratization of Ukrainian society confirms that democracy originates «from below», that is, with the personal participation of citizens in solving specific life issues that directly affect the conditions of their lives.

  4. Hydrothermal processing of Hanford tank waste. Organic destruction technology development task annual report -- FY 1993

    International Nuclear Information System (INIS)

    Orth, R.J.; Schmidt, A.J.; Zacher, A.H.

    1993-09-01

    Low-temperature hydrothermal processing (HTP) is a thermal-chemical autogenous processing method that can be used to destroy organics and ferrocyanide in Hanford tank waste at temperatures from 250 C to 400 C. With HTP, organics react with oxidants, such as nitrite and nitrate, already present in the waste. Ferrocyanides and free cyanide will hydrolyze at similar temperatures and may also react with nitrates or other oxidants in the waste. No air or oxygen or additional chemicals need to be added to the autogenous HTP system. However, enhanced kinetics may be realized by air addition, and, if desired, chemical reductants can be added to the system to facilitate complete nitrate/nitrate destruction. Tank waste can be processed in a plug-flow, tubular reactor, or a continuous-stirred tank reactor system designed to accommodate the temperature, pressure, gas generation, and heat release associated with decomposition of the reactive species. The work described in this annual report was conducted in FY 1993 for the Organic Destruction Technology Development Task of Hanford's Tank Waste Remediation System (TWRS). This task is part of an overall program to develop organic destruction technologies originally funded by TWRS to meet tank safety and waste form disposal criteria and condition the feed for further pretreatment. During FY 1993 the project completed seven experimental test plans, a 30-hr pilot-scale continuous run, over 200 hr of continuous bench-scale HTP testing, and 20 batch HTP tests; two contracts were established with commercial vendors, and a commercial laboratory reactor was procured and installed in a glovebox for HTP testing with actual Hanford tank waste

  5. Origin of Chlorobenzene Detected by the Curiosity Rover in Yellowknife Bay: Evidence for Martian Organics in the Sheepbed Mudstone?

    Science.gov (United States)

    Glavin, Daniel P.; Freissinet, Caroline; Eigenbrode, J.; Miller, K.; Martin, M.; Summons, R.; Steele, A.; Franz, H.; Archer, D.; Brinkerhoff, W.; hide

    2014-01-01

    The Sample Analysis at Mars (SAM) instrument on the Curiosity rover is designed to determine the inventory of organic and inorganic volatiles thermally evolved from solid samples using a combination of evolved gas analysis (EGA), gas chromatography mass spectrometry (GCMS), and tunable laser spectroscopy. The first solid samples analyzed by SAM, a scoop of windblown dust and sand at Rocknest (RN), revealed chlorinated hydrocarbons derived primarily from reactions between a martian oxychlorine phase (e.g. perchlorate) and terrestrial carbon from N-methyl-N-(tert-butyldimethylsilyl)-trifluoroacetamide (MTBSTFA) vapor present in the SAM instrument background. Chlorobenzene (CBZ) was also identified by SAM GCMS at RN at trace levels (approx.0.007 nmol) and was attributed to the reaction of chlorine with the Tenax polymers used in the hydrocarbon traps. After the RN analyses, Curiosity traveled to Yellowknife Bay and drilled two separate holes designated John Klein (JK) and Cumberland (CB). Analyses of JK and CB by both SAM and the CheMin x-ray diffraction instrument revealed a mudstone consisting of approx.20 wt% smectite clays, which on Earth are known to aid the concentration and preservation of organic matter. In addition, higher abundances and a more diverse suite of chlorinated hydrocarbons in CB compared to RN suggests that martian or meteoritic organic sources may be preserved in the mudstone. Here we discuss the SAM EGA and GCMS measurements of volatiles released from the Sheepbed mudstone. We focus primarily on the elevated CBZ detections at CB and laboratory analog experiments conducted to help determine if CBZ is derived from primarily terrestrial, martian, or a combination of sources.

  6. Origin and distribution of hydrocarbons and organic matter in the surficial sediments of the Sfax-Kerkennah channel (Tunisia, Southern Mediterranean Sea)

    OpenAIRE

    Zaghden, H.; Tedetti, Marc; Sayadi, S.; Serbaji, M. M.; Elleuch, B.; Saliot, A.

    2017-01-01

    International audience; We investigated the origin and distribution of aliphatic and polycyclic aromatic hydrocarbons (AHs and PAHs)and organic matter (OM) in surficial sediments of the Sfax-Kerkennah channel in the Gulf of Gabès (Tunisia,Southern Mediterranean Sea). TOC, AH and PAH concentrations ranged 2.3–11.7%, 8–174 μg g−1 sed. dw and175–10,769 ng g−1 sed. dw, respectively. The lowest concentrations were recorded in the channel (mediumsand sediment) and the highest ones in the Sfax harbo...

  7. Origin and processing of terrestrial organic carbon in the Amazon system: lignin phenols in river, shelf, and fan sediments

    Science.gov (United States)

    Sun, Shuwen; Schefuß, Enno; Mulitza, Stefan; Chiessi, Cristiano M.; Sawakuchi, André O.; Zabel, Matthias; Baker, Paul A.; Hefter, Jens; Mollenhauer, Gesine

    2017-05-01

    The Amazon River transports large amounts of terrestrial organic carbon (OCterr) from the Andean and Amazon neotropical forests to the Atlantic Ocean. In order to compare the biogeochemical characteristics of OCterr in the fluvial sediments from the Amazon drainage basin and in the adjacent marine sediments, we analysed riverbed sediments from the Amazon mainstream and its main tributaries as well as marine surface sediments from the Amazon shelf and fan for total organic carbon (TOC) content, organic carbon isotopic composition (δ13CTOC), and lignin phenol compositions. TOC and lignin content exhibit positive correlations with Al / Si ratios (indicative of the sediment grain size) implying that the grain size of sediment discharged by the Amazon River plays an important role in the preservation of TOC and leads to preferential preservation of lignin phenols in fine particles. Depleted δ13CTOC values (-26.1 to -29.9 ‰) in the main tributaries consistently correspond with the dominance of C3 vegetation. Ratios of syringyl to vanillyl (S / V) and cinnamyl to vanillyl (C / V) lignin phenols suggest that non-woody angiosperm tissues are the dominant source of lignin in the Amazon basin. Although the Amazon basin hosts a rich diversity of vascular plant types, distinct regional lignin compositions are not observed. In the marine sediments, the distribution of δ13CTOC and Λ8 (sum of eight lignin phenols in organic carbon (OC), expressed as mg/100 mg OC) values implies that OCterr discharged by the Amazon River is transported north-westward by the North Brazil Current and mostly deposited on the inner shelf. The lignin compositions in offshore sediments under the influence of the Amazon plume are consistent with the riverbed samples suggesting that processing of OCterr during offshore transport does not change the encoded source information. Therefore, the lignin compositions preserved in these offshore sediments can reliably reflect the vegetation in the Amazon

  8. Reclamation of cadmium-contaminated soil using dissolved organic matter solution originating from wine-processing waste sludge

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Cheng-Chung, E-mail: ccliu@niu.edu.tw [Department of Environmental Engineering, National Ilan University, Ilan, 260, Taiwan (China); Chen, Guan-Bu [Department of Environmental Engineering, National Ilan University, Ilan, 260, Taiwan (China)

    2013-01-15

    Highlights: ► Increases in acidity, washing frequency, and operational temperature enhance the Cd removal. ► Approximately 80% of Cd can be removed from the soil by dissolved organic matter (DOM) washing. ► The DOM washing can moderate the loss of soil fertility. ► The DOM washing will have a great improvement if we employ NaOH, KOH, Ca(OH){sub 2}, and Mg(OH){sub 2} to prepare the DOM solution together. -- Abstract: Soil washing using an acid solution is a common practice for removing heavy metals from contaminated soil in Taiwan. However, serious loss of nutrients from soil is a major drawback of the washing. Distillery sludge can be used to prepare a dissolved organic matter (DOM) solution by extracting its organic constituents with alkaline solutions. This study employed DOM solutions to remediate Cd-contaminated soil (with concentrations up to 21.5 mg kg{sup −1}) and determine the factors affecting removal of Cd, such as pH, initial concentration of DOM solution, temperature, and washing frequency. When washing with pH 3.0 and 1250 mg L{sup −1} DOM solution, about 80% and 81% of Cd were removed from the topsoil at 27 °C and subsoil at 40 °C, respectively. To summarize the changes in fertility during DOM washing with various pH solutions: the increase in organic matter content ranged from 7.7% to 23.7%; cation exchange capacity (CEC) ranged from 4.6% to 13.9%; available ammonium (N-NH{sub 4}) content ranged from 39.4% to 2175%; and available phosphorus content ranged from 34.5% to 182%. Exchangeable K, Ca, and Mg remained in the topsoil after DOM washing, with concentrations of 1.1, 2.4, and 1.5 times higher than those treated with HCl solution at the same pH, respectively.

  9. Original Researc Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    Practices. Problems. Supervision. Primary School. *Corresponding Author: Asrat Dagnew. E-mail: asratboza@yahoo.com tructional support. The relevant and ... vision is one of indispensable system pment. Supervision is a system of that directly concerned on the aff members in a school or other. Original Research ...

  10. Development of Polymer Acceptors for Organic Photovoltaic Cells

    Directory of Open Access Journals (Sweden)

    Yujeong Kim

    2014-02-01

    Full Text Available This review provides a current status report of the various n-type polymer acceptors for use as active materials in organic photovoltaic cells (OPVs. The polymer acceptors are divided into four categories. The first section of this review focuses on rylene diimide-based polymers, including perylene diimide, naphthalene diimide, and dithienocoronene diimide-based polymers. The high electron mobility and good stability of rylene diimides make them suitable for use as polymer acceptors in OPVs. The second section deals with fluorene and benzothiadiazole-based polymers such as poly(9,9’-dioctylfluorene-co-benzothiadiazole, and the ensuing section focuses on the cyano-substituted polymer acceptors. Cyano-poly(phenylenevinylene and poly(3-cyano-4-hexylthiophene have been used as acceptors in OPVs and exhibit high electron affinity arising from the electron-withdrawing cyano groups in the vinylene group of poly(phenylenevinylene or the thiophene ring of polythiophene. Lastly, a number of other electron-deficient groups such as thiazole, diketopyrrolopyrrole, and oxadiazole have also been introduced onto polymer backbones to induce n-type characteristics in the polymer. Since the first report on all-polymer solar cells in 1995, the best power conversion efficiency obtained with these devices to date has been 3.45%. The overall trend in the development of n-type polymer acceptors is presented in this review.

  11. Origin and alteration of organic matter in termite mounds from different feeding guilds of the Amazon rainforests.

    Science.gov (United States)

    Siebers, Nina; Martius, Christopher; Eckhardt, Kai-Uwe; Garcia, Marcos V B; Leinweber, Peter; Amelung, Wulf

    2015-01-01

    The impact of termites on nutrient cycling and tropical soil formation depends on their feeding habits and related material transformation. The identification of food sources, however, is difficult, because they are variable and changed by termite activity and nest construction. Here, we related the sources and alteration of organic matter in nests from seven different termite genera and feeding habits in the Terra Firme rainforests to the properties of potential food sources soil, wood, and microepiphytes. Chemical analyses comprised isotopic composition of C and N, cellulosic (CPS), non-cellulosic (NCPS), and N-containing saccharides, and molecular composition screening using pyrolysis-field ionization mass spectrometry (Py-FIMS). The isotopic analysis revealed higher soil δ13C (-27.4‰) and δ15N (6.6‰) values in nests of wood feeding Nasutitermes and Cornitermes than in wood samples (δ13C = -29.1‰, δ15N = 3.4‰), reflecting stable-isotope enrichment with organic matter alterations during or after nest construction. This result was confirmed by elevated NCPS:CPS ratios, indicating a preferential cellulose decomposition in the nests. High portions of muramic acid (MurAc) pointed to the participation of bacteria in the transformation processes. Non-metric multidimensional scaling (MDS) revealed increasing geophagy in the sequence Termes rainforest termites shows variations and evidence of modification by microbial processes, but nevertheless it primarily reflects the trophic niches of the constructors.

  12. Origin and Alteration of Organic Matter in Termite Mounds from Different Feeding Guilds of the Amazon Rainforests

    Science.gov (United States)

    Siebers, Nina; Martius, Christopher; Eckhardt, Kai-Uwe; Garcia, Marcos V. B.; Leinweber, Peter; Amelung, Wulf

    2015-01-01

    The impact of termites on nutrient cycling and tropical soil formation depends on their feeding habits and related material transformation. The identification of food sources, however, is difficult, because they are variable and changed by termite activity and nest construction. Here, we related the sources and alteration of organic matter in nests from seven different termite genera and feeding habits in the Terra Firme rainforests to the properties of potential food sources soil, wood, and microepiphytes. Chemical analyses comprised isotopic composition of C and N, cellulosic (CPS), non-cellulosic (NCPS), and N-containing saccharides, and molecular composition screening using pyrolysis-field ionization mass spectrometry (Py-FIMS). The isotopic analysis revealed higher soil δ13C (-27.4‰) and δ15N (6.6‰) values in nests of wood feeding Nasutitermes and Cornitermes than in wood samples (δ13C = -29.1‰, δ15N = 3.4‰), reflecting stable-isotope enrichment with organic matter alterations during or after nest construction. This result was confirmed by elevated NCPS:CPS ratios, indicating a preferential cellulose decomposition in the nests. High portions of muramic acid (MurAc) pointed to the participation of bacteria in the transformation processes. Non-metric multidimensional scaling (NMDS) revealed increasing geophagy in the sequence Termes termites shows variations and evidence of modification by microbial processes, but nevertheless it primarily reflects the trophic niches of the constructors. PMID:25909987

  13. Quadruple sulfur isotope constraints on the origin and cycling of volatile organic sulfur compounds in a stratified sulfidic lake

    Science.gov (United States)

    Oduro, Harry; Kamyshny, Alexey; Zerkle, Aubrey L.; Li, Yue; Farquhar, James

    2013-11-01

    We have quantified the major forms of volatile organic sulfur compounds (VOSCs) distributed in the water column of stratified freshwater Fayetteville Green Lake (FGL), to evaluate the biogeochemical pathways involved in their production. The lake's anoxic deep waters contain high concentrations of sulfate (12-16 mmol L-1) and sulfide (0.12 μmol L-1 to 1.5 mmol L-1) with relatively low VOSC concentrations, ranging from 0.1 nmol L-1 to 2.8 μmol L-1. Sulfur isotope measurements of combined volatile organic sulfur compounds demonstrate that VOSC species are formed primarily from reduced sulfur (H2S/HS-) and zero-valent sulfur (ZVS), with little input from sulfate. Thedata support a role of a combination of biological and abiotic processes in formation of carbon-sulfur bonds between reactive sulfur species and methyl groups of lignin components. These processes are responsible for very fast turnover of VOSC species, maintaining their low levels in FGL. No dimethylsulfoniopropionate (DMSP) was detected by Electrospray Ionization Mass Spectrometry (ESI-MS) in the lake water column or in planktonic extracts. These observations indicate a pathway distinct from oceanic and coastal marine environments, where dimethylsulfide (DMS) and other VOSC species are principally produced via the breakdown of DMSP by plankton species.

  14. Reaching the grassroots: publishing methodologies for development organizations.

    Science.gov (United States)

    Zielinski, C

    1987-01-01

    There are 3 major distinctions between the traditional form of academic publishing and publishing for the grassroots as a development-organization activity, particularly in developing countries. Whereas academic publishing seeks to cover the target audience in its entirety, grassroots publishing can only cover a sampling. Academic publishing fulfills a need, while grassroots publishing demonstrates a need and a way to fulfill it. Finally, whereas academic publishing is largely a support activity aimed at facilitating the dissemination of information as a relatively minor part of a technical program, grassroots publishing is a more substantive activity aimed at producing a catalytic effect. Publication for the grassroots further calls for a different methodological approach. Given the constraint of numbers, publications aimed at the grassroots can only be examples or prototypes. The function of a prototype is to serve both as a basis for translation, adaptation, and replication and as a model end result. The approach to the use and promotion of prototypes differs according to the specific country situation. In countries with a heterogenous culture or several different languages, 2 items should be produced: a prototype of the complete text, which should be pretested and evaluated, and a prototype adaptation kit stripped of cultural and social biases. Promotion of the translation and replication of a publication can be achieved by involving officials at the various levels of government, interesting international and voluntary funding agencies, and stimulating indigenous printing capacities at the community level. The most important factors are the appropriateness of the publication in solving specific priority problems and the interest and involvement of national and state authorities at all stages of the project.

  15. The Transcendent Organization : A treatise on consciousness in organizations: theoretical discussion, conceptual development and empirical studies

    OpenAIRE

    Gustavsson, Bengt

    1992-01-01

    Organizations are human constructs, and unless the organizational analysis takes into account a wider discussion of the relationship between the subject and the object the analysis ends up in relativism, anarchism, and confusion. There is a danger when we make the organization objective to such extent that it is viewed as an entity outside ourselves. Understanding of an organization is a collective phenomenon given by the prevailing fundamental assumptions in society, and is transferred by sy...

  16. Institutions of Family Support and Assistance. The Origin, the Functions and the Organization of the District Family Assistance Centre

    Directory of Open Access Journals (Sweden)

    KATARZYNA OLCZAK-BARAN

    2017-10-01

    Full Text Available In my paper I would like to present the origin and the main tasks of the DFAC. In my article I also mention other institutions of family support which might help to improve the functioning of this basic unit of society. The work of those institutions is especially important in case of families having a disorder, in connection with the performance of its basic functions of care and education – in relation to children, the disabled, elderly people and also young people who require preventive actions and rehabilitation. It is essential to know the tasks and the role of DFAC, because of the increasing number of juvenile offenders and the parents' upbringing and caring failure. Such disorders are caused by difficult situation of people under protection of child and family support institutions, in connection with unemployment, poverty, and helplessness. Such families and single units as well should be given care and one should show them the way to solve their problems. Today, the institutions such as DFAC, homes for mothers with infant children or the National Emergency Service for Victims of Domestic Violence are one of the most important and necessary in helping the families. They can help to improve the quality of whole society's life as well as to increase self-esteem of people who feel lost and who are looking for their place in life

  17. Towards High Performance Organic Photovoltaic Cells: A Review of Recent Development in Organic Photovoltaics

    Directory of Open Access Journals (Sweden)

    Junsheng Yu

    2014-09-01

    Full Text Available Organic photovoltaic cells (OPVs have been a hot topic for research during the last decade due to their promising application in relieving energy pressure and environmental problems caused by the increasing combustion of fossil fuels. Much effort has been made toward understanding the photovoltaic mechanism, including evolving chemical structural motifs and designing device structures, leading to a remarkable enhancement of the power conversion efficiency of OPVs from 3% to over 15%. In this brief review, the advanced progress and the state-of-the-art performance of OPVs in very recent years are summarized. Based on several of the latest developed approaches to accurately detect the separation of electron-hole pairs in the femtosecond regime, the theoretical interpretation to exploit the comprehensive mechanistic picture of energy harvesting and charge carrier generation are discussed, especially for OPVs with bulk and multiple heterojunctions. Subsequently, the novel structural designs of the device architecture of OPVs embracing external geometry modification and intrinsic structure decoration are presented. Additionally, some approaches to further increase the efficiency of OPVs are described, including thermotics and dynamics modification methods. Finally, this review highlights the challenges and prospects with the aim of providing a better understanding towards highly efficient OPVs.

  18. Development of Molecular Markers for Determining Continental Origin of Wood from White Oaks (Quercus L. sect. Quercus.

    Directory of Open Access Journals (Sweden)

    Hilke Schroeder

    Full Text Available To detect and avoid illegal logging of valuable tree species, identification methods for the origin of timber are necessary. We used next-generation sequencing to identify chloroplast genome regions that differentiate the origin of white oaks from the three continents; Asia, Europe, and North America. By using the chloroplast genome of Asian Q. mongolica as a reference, we identified 861 variant sites (672 single nucleotide polymorphisms (SNPs; 189 insertion/deletion (indel polymorphism from representative species of three continents (Q. mongolica from Asia; Q. petraea and Q. robur from Europe; Q. alba from North America, and we identified additional chloroplast polymorphisms in pools of 20 individuals each from Q. mongolica (789 variant sites and Q. robur (346 variant sites. Genome sequences were screened for indels to develop markers that identify continental origin of oak species, and that can be easily evaluated using a variety of detection methods. We identified five indels and one SNP that reliably identify continent-of-origin, based on evaluations of up to 1078 individuals representing 13 white oak species and three continents. Due to the size of length polymorphisms revealed, this marker set can be visualized using capillary electrophoresis or high resolution gel (acrylamide or agarose electrophoresis. With these markers, we provide the wood trading market with an instrument to comply with the U.S. and European laws that require timber companies to avoid the trade of illegally harvested timber.

  19. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    ic antiretroviral treatments, World Health Organization r all exposed infants to ... eir cell differentiation 4 plus ts. ... service provision was not uniformly initiated at all health facilities. ... or variance inflation rates (VIF) of greater than 10 as indicator ...

  20. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    organizing mathematics lessons, classroom managemen. Teachers have also ... method at an average level, their obstruction effect was implied that there are ..... non-significant difference between the expected (12) and the observed (12.35) ...

  1. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    genetic improvement and lack of organized market system are the ... Science, Technology and Arts Research Journ. Sci. ... located in Oromia Regional States in the western. Ethiopia ..... district in the western Ethiopia that reported the price of.

  2. Original Researc Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    MATERIALS AND METHODS. Study Area and ... establish replicated planting materials at each home .... content (Sankaram, 1996), organic carbon content, available ..... and measure most of the elements essential to plant nutrition as .... manipulate cocoyam canopy architecture, leaf production, planting .... Application of.

  3. Origin of Chlorobenzene Detected by the Curiosity Rover in Yellowknife Bay: Evidence for Martian Organics in the Sheepbed Mudstone

    Science.gov (United States)

    Glavin, D.; Freissnet, C.; Eigenbrode, J.; Miller, K.; Martin, M.; Summons, R. E.; Steele, A.; Archer, D.; Brunner, A.; Buch, A.; hide

    2014-01-01

    The Sample Analysis at Mars (SAM) instrument on the Curiosity rover is designed to determine the inventory of organic and inorganic volatiles thermally evolved from solid samples using a combination of evolved gas analysis (EGA), gas chromatography mass spectrometry (GCMS), and tunable laser spectroscopy. Here we discuss the SAM EGA and GCMS measurements of volatiles released from the Sheepbed mudstone. We focus primarily on the elevated CBZ detections at CB and laboratory analog experiments conducted to help determine if CBZ is derived from primarily terrestrial, martian, or a combination of sources. Here we discuss the SAM EGA and GCMS measurements of volatiles released from the Sheepbed mudstone. We focus primarily on the elevated CBZ detections at CB and laboratory analog experiments conducted to help determine if CBZ is derived from primarily terrestrial, martian, or a combination of sources.

  4. [Organization, availability and possibility of analysis of disaster data of climate related origin and its impacts on health].

    Science.gov (United States)

    Xavier, Diego Ricardo; Barcellos, Christovam; Barros, Heglaucio da Silva; Magalhães, Monica de Avelar Figueiredo Mafra; Matos, Vanderlei Pascoal de; Pedroso, Marcel de Moraes

    2014-09-01

    The occurrence of disasters is often related to unforeseeable able natural processes. However, the analysis of major databases may highlight seasonal and long-term trends, as well as some spatial patterns where risks are concentrated. In this paper the process of acquiring and organizing climate-related disaster data collected by civil protection institutions and made available by the Brazilian Climate and Health Observatory is described. Preliminary analyses show the concentration of disasters caused by heavy rainfall events along the Brazilian coastline especially during the summer. Droughts have longer duration and extent, affecting large areas of the south and northeast regions of the country. These data can be used to analyze and monitor the impact of extreme climatic events on health, as well as identify the vulnerability and climate deteminants.

  5. Origin and distribution of the organic matter in the distal lobe of the Congo deep-sea fan - A Rock-Eval survey

    Science.gov (United States)

    Baudin, François; Stetten, Elsa; Schnyder, Johann; Charlier, Karine; Martinez, Philippe; Dennielou, Bernard; Droz, Laurence

    2017-08-01

    The Congo River, the second largest river in the world, is a major source of organic matter for the deep Atlantic Ocean because of the connection of its estuary to the deep offshore area by a submarine canyon which feeds a vast deep-sea fan. The lobe zone of this deep-sea fan is the final receptacle of the sedimentary inputs presently channelled by the canyon and covers an area of 2500 km². The quantity and the source of organic matter preserved in recent turbiditic sediments from the distal lobe of the Congo deep-sea fan were assessed using Rock-Eval pyrolysis analyses. Six sites, located at approximately 5000 m water-depth, were investigated. The mud-rich sediments of the distal lobe contain high amounts of organic matter ( 3.5 to 4% Corg), the origin of which is a mixture of terrestrial higher-plant debris, soil organic matter and deeply oxidized phytoplanktonic material. Although the respective contribution of terrestrial and marine sources of organic matter cannot be precisely quantified using Rock-Eval analyses, the terrestrial fraction is dominant according to similar hydrogen and oxygen indices of both suspended and bedload sediments from the Congo River and that deposited in the lobe complex. The Rock-Eval signature supports the 70% to 80% of the terrestrial fraction previously estimated using C/N and δ13Corg data. In the background sediment, the organic matter distribution is homogeneous at different scales, from a single turbiditic event to the entire lobe, and changes in accumulation rates only have a limited effect on the quantity and quality of the preserved organic matter. Peculiar areas with chemosynthetic bivalves and/or bacterial mats, explored using ROV Victor 6000, show a Rock-Eval signature similar to background sediment. This high organic carbon content associated to high sedimentation rates (> 2 to 20 mm.yr-1) in the Congo distal lobe complex implies a high burial rate for organic carbon. Consequently, the Congo deep-sea fan represents an

  6. Microstructural and Electronic Origins of Open-Circuit Voltage Tuning in Organic Solar Cells Based on Ternary Blends

    KAUST Repository

    Mollinger, Sonya A.

    2015-09-22

    © 2015 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. Organic ternary heterojunction photovoltaic blends are sometimes observed to undergo a gradual evolution in open-circuit voltage (Voc) with increasing amounts of a second donor or an acceptor. The Voc is strongly correlated with the energy of the charge transfer state in the blend, but this value depends on both local and mesoscopic orders. In this work, the behavior of Voc in the presence of a wide range of interfacial electronic states is investigated. The key charge transfer state interfaces responsible for Voc in several model systems with varying morphology are identified. Systems consisting of one donor with two fullerene molecules and of one acceptor with a donor polymer of varying regio-regularity are used. The effects from the changing energetic disorder in the material and from the variation due to a law of simple mixtures are quantified. It has been found that populating the higher-energy charge transfer states is not responsible for the observed change in Voc upon the addition of a third component. Aggregating polymers and miscible fullerenes are compared, and it has been concluded that in both cases charge delocalization, aggregation, and local polarization effects shift the lowest-energy charge transfer state distribution. The open-circuit voltage evolution and charge transfer state interfaces in ternary organic photovoltaic blends are investigated using several model systems. The changes in subgap spectra from energetic disorder and increased population of higher energy states are analyzed and the lowest charge transfer state distribution is observed to shift due to local aggregation and delocalization effects.

  7. Origin and alteration of organic matter in termite mounds from different feeding guilds of the Amazon rainforests.

    Directory of Open Access Journals (Sweden)

    Nina Siebers

    Full Text Available The impact of termites on nutrient cycling and tropical soil formation depends on their feeding habits and related material transformation. The identification of food sources, however, is difficult, because they are variable and changed by termite activity and nest construction. Here, we related the sources and alteration of organic matter in nests from seven different termite genera and feeding habits in the Terra Firme rainforests to the properties of potential food sources soil, wood, and microepiphytes. Chemical analyses comprised isotopic composition of C and N, cellulosic (CPS, non-cellulosic (NCPS, and N-containing saccharides, and molecular composition screening using pyrolysis-field ionization mass spectrometry (Py-FIMS. The isotopic analysis revealed higher soil δ13C (-27.4‰ and δ15N (6.6‰ values in nests of wood feeding Nasutitermes and Cornitermes than in wood samples (δ13C = -29.1‰, δ15N = 3.4‰, reflecting stable-isotope enrichment with organic matter alterations during or after nest construction. This result was confirmed by elevated NCPS:CPS ratios, indicating a preferential cellulose decomposition in the nests. High portions of muramic acid (MurAc pointed to the participation of bacteria in the transformation processes. Non-metric multidimensional scaling (MDS revealed increasing geophagy in the sequence Termes < Embiratermes < Anoplotermes and increasing xylophagy for Cornitermes < Nasutitermes., and that the nest material of Constrictotermes was similar to the microepiphytes sample, confirming the report that Constrictotermes belongs to the microepiphyte-feeders. We therewith document that nest chemistry of rainforest termites shows variations and evidence of modification by microbial processes, but nevertheless it primarily reflects the trophic niches of the constructors.

  8. The origin and evolution of chondrites recorded in the elemental and isotopic compositions of their macromolecular organic matter

    Science.gov (United States)

    Alexander, C. M. O.'D.; Fogel, M.; Yabuta, H.; Cody, G. D.

    2007-09-01

    Extraterrestrial organic matter in meteorites potentially retains a unique record of synthesis and chemical/thermal modification by parent body, nebular and even presolar processes. In a survey of the elemental and isotopic compositions of insoluble organic matter (IOM) from 75 carbonaceous, ordinary and enstatite chondrites, we find dramatic variations within and between chondrite classes. There is no evidence that these variations correlate with the time and/or location of chondrite formation, or with any primary petrologic or bulk compositional features that are associated with nebular processes (e.g., chondrule and volatile trace element abundances). Nor is there evidence for the formation of the IOM by Fischer-Tropsch-Type synthesis in the nebula or in the parent bodies. The elemental variations are consistent with thermal maturation and/or oxidation of a common precursor. For reasons that are unclear, there are large variations in isotopic composition within and between chondrite classes that do not correlate in a simple way with elemental composition or petrologic type. Nevertheless, because of the pattern of elemental variations with petrologic type and the lack of any correlation with the primary features of the chondrite classes, at present the most likely explanation is that all IOM compositional variations are the result of parent body processing of a common precursor. If correct, the range of isotopic compositions within and between chondrite classes implies that the IOM is composed of several isotopically distinct components whose relative stability varied with parent body conditions. The most primitive IOM is found in the CR chondrites and Bells (CM2). Isotopically, the IOM from these meteorites resembles the IOM in interplanetary dust particles. Chemically, their IOM resembles the CHON particles of comet Halley. Despite the large isotopic anomalies in the IOM from these meteorites, it is uncertain whether the IOM formed in the interstellar medium or

  9. Origin of inorganic and organic components of PM_2_._5 in subway stations of Barcelona, Spain

    International Nuclear Information System (INIS)

    Martins, Vânia; Moreno, Teresa; Minguillón, María Cruz; Drooge, Barend L. van; Reche, Cristina; Amato, Fulvio; Miguel, Eladio de; Capdevila, Marta; Centelles, Sonia; Querol, Xavier

    2016-01-01

    The present work assesses indoor air quality in stations of the Barcelona subway system. PM_2_._5 concentrations on the platforms of 4 subway stations were measured during two different seasons and the chemical composition was determined. A Positive Matrix Factorization analysis was performed to identify and quantify the contributions of major PM_2_._5 sources in the subway stations. Mean PM_2_._5 concentrations varied according to the stations design and seasonal periods. PM_2_._5 was composed of haematite, carbonaceous aerosol, crustal matter, secondary inorganic compounds, trace elements, insoluble sulphate and halite. Organic compounds such as PAHs, nicotine, levoglucosan and aromatic musk compounds were also identified. Subway PM_2_._5 source comprised emissions from rails, wheels, catenaries, brake pads and pantographs. The subway source showed different chemical profiles for each station, but was always dominated by Fe. Control actions on the source are important for the achievement of better air quality in the subway environment. - Highlights: • PM_2_._5 concentrations varied according to stations design and seasonal periods. • Haematite was the most abundant component of PM_2_._5. • Organic compounds such as PAHs were detected in the subway stations. • The subway contribution to ambient PM_2_._5 on the platforms ranged from 9 to 58%. • The chemical profile of the subway emissions varies depending on the station. - Concentrations of PM_2_._5 chemical components varied according to stations design, seasonal periods, and chemical composition of rail, catenary and trains. PM_2_._5 consists mainly of Fe.

  10. Microstructural and Electronic Origins of Open-Circuit Voltage Tuning in Organic Solar Cells Based on Ternary Blends

    KAUST Repository

    Mollinger, Sonya A.; Vandewal, Koen; Salleo, Alberto

    2015-01-01

    © 2015 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. Organic ternary heterojunction photovoltaic blends are sometimes observed to undergo a gradual evolution in open-circuit voltage (Voc) with increasing amounts of a second donor or an acceptor. The Voc is strongly correlated with the energy of the charge transfer state in the blend, but this value depends on both local and mesoscopic orders. In this work, the behavior of Voc in the presence of a wide range of interfacial electronic states is investigated. The key charge transfer state interfaces responsible for Voc in several model systems with varying morphology are identified. Systems consisting of one donor with two fullerene molecules and of one acceptor with a donor polymer of varying regio-regularity are used. The effects from the changing energetic disorder in the material and from the variation due to a law of simple mixtures are quantified. It has been found that populating the higher-energy charge transfer states is not responsible for the observed change in Voc upon the addition of a third component. Aggregating polymers and miscible fullerenes are compared, and it has been concluded that in both cases charge delocalization, aggregation, and local polarization effects shift the lowest-energy charge transfer state distribution. The open-circuit voltage evolution and charge transfer state interfaces in ternary organic photovoltaic blends are investigated using several model systems. The changes in subgap spectra from energetic disorder and increased population of higher energy states are analyzed and the lowest charge transfer state distribution is observed to shift due to local aggregation and delocalization effects.

  11. Development on traceability based on changes of stable isotopes in animal tissues and organs

    International Nuclear Information System (INIS)

    Cai Xianfeng; Guo Boli; Wei Yimin; Sun Shumin; Wei Shuai

    2011-01-01

    Stable isotope analysis is a new method in food traceability, which can be used to trace animals' geographical origin and life history. This paper reviews the recent progress of researches on characteristics of stable isotopes and turnover time in different animal tissues and organs, as well as their influence caused by feed, drinking water, geographical origin, storing and processing. The aim of this paper is to provide theoretical reference for studies on the traceability of animal derived food and animals' life history. (authors)

  12. Kölliker’s Organ and the Development of Spontaneous Activity in the Auditory System: Implications for Hearing Dysfunction

    Directory of Open Access Journals (Sweden)

    M. W. Nishani Dayaratne

    2014-01-01

    Full Text Available Prior to the “onset of hearing,” developing cochlear inner hair cells (IHCs and primary auditory neurons undergo experience-independent activity, which is thought to be important in retaining and refining neural connections in the absence of sound. One of the major hypotheses regarding the origin of such activity involves a group of columnar epithelial supporting cells forming Kölliker’s organ, which is only present during this critical period of auditory development. There is strong evidence for a purinergic signalling mechanism underlying such activity. ATP released through connexin hemichannels may activate P2 purinergic receptors in both Kölliker’s organ and the adjacent IHCs, leading to generation of electrical activity throughout the auditory system. However, recent work has suggested an alternative origin, by demonstrating the ability of IHCs to generate this spontaneous activity without activation by ATP. Regardless, developmental abnormalities of Kölliker’s organ may lead to congenital hearing loss, considering that mutations in ion channels (hemichannels, gap junctions, and calcium channels involved in Kölliker’s organ activity share strong links with such types of deafness.

  13. The aminoacyl-tRNA synthetases had only a marginal role in the origin of the organization of the genetic code: Evidence in favor of the coevolution theory.

    Science.gov (United States)

    Di Giulio, Massimo

    2017-11-07

    The coevolution theory of the origin of the genetic code suggests that the organization of the genetic code coevolved with the biosynthetic relationships between amino acids. The mechanism that allowed this coevolution was based on tRNA-like molecules on which-this theory-would postulate the biosynthetic transformations between amino acids to have occurred. This mechanism makes a prediction on how the role conducted by the aminoacyl-tRNA synthetases (ARSs), in the origin of the genetic code, should have been. Indeed, if the biosynthetic transformations between amino acids occurred on tRNA-like molecules, then there was no need to link amino acids to these molecules because amino acids were already charged on tRNA-like molecules, as the coevolution theory suggests. In spite of the fact that ARSs make the genetic code responsible for the first interaction between a component of nucleic acids and that of proteins, for the coevolution theory the role of ARSs should have been entirely marginal in the genetic code origin. Therefore, I have conducted a further analysis of the distribution of the two classes of ARSs and of their subclasses-in the genetic code table-in order to perform a falsification test of the coevolution theory. Indeed, in the case in which the distribution of ARSs within the genetic code would have been highly significant, then the coevolution theory would be falsified since the mechanism on which it is based would not predict a fundamental role of ARSs in the origin of the genetic code. I found that the statistical significance of the distribution of the two classes of ARSs in the table of the genetic code is low or marginal, whereas that of the subclasses of ARSs statistically significant. However, this is in perfect agreement with the postulates of the coevolution theory. Indeed, the only case of statistical significance-regarding the classes of ARSs-is appreciable for the CAG code, whereas for its complement-the UNN/NUN code-only a marginal

  14. Organization and development of the Brazilian nuclear program

    International Nuclear Information System (INIS)

    Pinto, C. Syllus M.; Alves, R. Nazare; Lepecki, W.; Costa, H.M. da; Grinberg, M.; Grimberg, M.

    1977-01-01

    The paper presents the Brazilian Nuclear Energy Program: its development until the present stage, as well as the organizations and the distribution of responsibilities involved in its execution at the present time. The nuclear power policy is established at the Presidency of the Republic and is planned, executed and controlled through the Ministry of Mines and Energy. Directly subject to the Ministry is the Brazilian Nuclear Energy Commission (CNEN), which has regulatory, standardization, licensing, planning and surveillance functions. The nuclear fundamental research and manpower formation are also under CNEN responsibility. Also subject to the Ministry are two companies responsible for the execution of the Programme: the Centrais Eletricas Brasileiras S.A. - ELETROBRAS, which advises on the granting of permits for the construction and operation of nuclear power plants, and the Empresas Nucleares Brasileiras S.A. - NUCLEBRAS, which holds the monopoly of the nuclear fuel cycle in the country, designs and builds nuclear power plants and provides assistance to the electric utilities as well as promotes the participation of the Brazilian industry in the nuclear field. Besides describing the new distribution of regulatory functions given by law to the CNEN, this paper gives special emphasis to the large industrial complex which is in the process of being established with the setting-up of the many NUCLEBRAS subsidiaries in joint-venture with German firms in the nuclear field, as a consequence of the Industrial Cooperation between Brazil and the Federal Republic of Germany in the Field of the Peaceful Uses of Nuclear Energy signed between the two countries on June 27, 1975. The programs for these subsidiaries are presented and their participation in the Brazilian Nuclear Energy Programme is discussed. The technology transfer aspects of the industrial activities are also discussed, based on the Government's policy on the subject [es

  15. Organization and development of the Brazilian nuclear programme

    International Nuclear Information System (INIS)

    Pinto, C.S.M.; Souza, J.A.M. de; Grinberg, M.; Alves, R.N.; Costa, H.M. da; Grimberg, M.

    1977-01-01

    The paper presents the Brazilian Nuclear Energy Programme, its development, the organizations and the distribution of responsibilities involved in its execution at the present time. The nuclear power policy is established at the Presidency of the Republic and is planned, executed and controlled through the Ministry of Mines and Energy. Directly subject to the Ministry is the Brazilian Nuclear Energy Commission (CNEN), which has regulatory, standardization, licensing, planning and surveillance functions. The nuclear fundamental research and manpower formation are also under CNEN responsibility. Also subject to the Ministry are two companies responsible for the execution of the Programme: the Centrais Eletricas Brasileiras S.A. - Eletrobras, which advises on the granting of permits for the construction and operation of nuclear power plants, and the Empresas Nucleares Brasileiras S.A. - Nuclebras, which holds the monopoly of the nuclear fuel cycle in the country, designs and builds nuclear power plants and provides assistance to the electric utilities and promotes the participation of Brazilian industry. Besides describing the new distribution of regulatory functions given by law to CNEN, the paper gives special emphasis to the large industrial complex in the process of being established through the setting-up of the many Nuclebras subsidiaries in joint venture with German firms under the Industrial Co-operation Agreement Between Brazil and the Federal Republic of Germany in the Field of the Peaceful Uses of Nuclear Energy. The programmes for these subsidiaries are presented and their participation in the Brazilian Nuclear Energy Programme is discussed. The technology transfer aspects of the industrial activities are also discussed. (author)

  16. Associations between and development of welfare indicators in organic layers

    DEFF Research Database (Denmark)

    Hinrichsen, Lena Karina; Riber, Anja Brinch; Labouriau, Rodrigo

    2016-01-01

    The retail market share of organic eggs in Denmark is high, and the consumers expect high animal welfare standards in the organic production. Documentation of animal welfare is important, however, knowledge about the associations between animal-based welfare indicators is limited. The aims......, keel bone damages, back feathering, body feathering, foot damages, comb colour and wounds on the body. An observational study with 12 organic egg farms was conducted in 2012 and 2013 with a total of 214 hens assessed individually at the peak and the end of lay. Insufficient data were obtained...

  17. Development and applications of TOHR, an original emission tomography system, adapted to small animals

    International Nuclear Information System (INIS)

    Ploux, Lydie

    1997-01-01

    For many neuro-biological studies, it is necessary to link microscopic aspects of the brain's organization with integrated brain functions. Details of the former are obtained by in vitro and in situ molecular biology techniques, whereas the latter are acquired through behavioural studies. In vivo radio-imaging methods, like emission tomography are the ideal tools to investigate the links between these two levels of brain organization. The work which is presented here focuses on a new approach of emission tomography adapted to small animal studies: TOHR (French, acronym for TOmographe Haute Resolution). The principle is based on the use of a large solid angle, high resolution and high efficiency focusing collimator. High resolution and high signal to noise ratio are improved by using nuclides having a two-photon decay with small angular correlation ( 125 I, 123 I, 111 In,...). The image is built step-by-step, by moving the animal relative to the collimator focal point. First, numerical simulation showed the possibility of reaching sub-millimetric resolutions; these results led to the collimator geometry (at present 10 over the 20 faces of an icosahedron, 15 faces in the future). Then, a prototype of TOHR has been built and characterized. Its performance is very close to the numerical prediction: spatial resolution of 1.4 mm and detection efficiency 0.64%. Finally, experiments on a rat thyroid allowed the preparation and realization of the first experiments on a rat striatum. The good quality of these images shows that it is now possible to evaluate TOHR capabilities on a dopaminergic neuron degeneration model in rats in the field of neuro-degenerative disease studies. (author)

  18. Striation and slickenline development on quartz fault surfaces at crustal conditions : Origin and effect on friction

    NARCIS (Netherlands)

    Toy, Virginia G.; Niemeijer, André; Renard, Francois; Morales, Luiz; Wirth, Richard

    Fragments of optically flat silica discs embedded in synthetic gouge were deformed to examine the relationship between the development of striations and slickenlines, and deformation mechanisms, conditions, and fault rheology. Experiments were performed under hydrothermal conditions in a rotary

  19. Development of additional pituitary hormone deficiencies in pediatric patients originally diagnosed with idiopathic isolated GH deficiency

    NARCIS (Netherlands)

    W.F. Blum (Werner); C.L. Deal (Cheri Lynn); A.G. Zimmermann (Alan); E.P. Shavrikova (Elena); C.J. Child (Christopher); C.A. Quigley (Charmian); S.L.S. Drop (Stenvert); G. Cutler (Gordon); R.G. Rosenfeld (Ron)

    2014-01-01

    textabstractObjective: We assessed the characteristics of children initially diagnosed with idiopathic isolated GH deficiency (IGHD) who later developed additional (multiple) pituitary hormone deficiencies (MPHD). Design: Data were analyzed for 5805 pediatric patients with idiopathic IGHD, who were

  20. Influence of contemporary carbon originating from the 2003 Siberian forest fire on organic carbon in PM2.5 in Nagoya, Japan.

    Science.gov (United States)

    Ikemori, Fumikazu; Honjyo, Koji; Yamagami, Makiko; Nakamura, Toshio

    2015-10-15

    In May 2003, high concentrations of organic carbon (OC) in PM2.5 were measured in Nagoya, a representative metropolitan area in Japan. To investigate the influence of possible forest fires on PM2.5 in Japan via long-range aerosol transport, the radiocarbon ((14)C) concentrations of PM2.5 samples from April 2003 to March 2004 were measured. (14)C concentrations in total carbon (TC) from May to early June showed higher values than those in other periods. The OC/elemental carbon (EC) ratios from May to early June were also significantly higher than the ones in other periods. In addition, OC concentrations from May to early June were typically high. These results indicate that the abundant OC fraction from May to early June in Nagoya consisted predominantly of contemporary carbon. Furthermore, simulations of diffusion and transport of organic matter (OM) in East Asia showed that abundant OM originating from East Siberia spread over East Asia and Japan in May and early June. Backward air mass trajectories from this time frame indicate that the air mass in Nagoya likely first passed through East Siberia where fire events were prevalent. However, the backward trajectories showed that the air mass after early June did not originate mainly from Siberia, and correspondingly, the (14)C and OC concentrations showed lower values than those from May to early June. Therefore, the authors conclude that contemporary carbon originating from the forest fire in East Siberia was transported to Nagoya, where it significantly contributed to the high observed concentrations of both OC and (14)C. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. Development and assessment of a lysophospholipid-based deep learning model to discriminate geographical origins of white rice.

    Science.gov (United States)

    Long, Nguyen Phuoc; Lim, Dong Kyu; Mo, Changyeun; Kim, Giyoung; Kwon, Sung Won

    2017-08-17

    Geographical origin determination of white rice has become the major issue of food industry. However, there is still lack of a high-throughput method for rapidly and reproducibly differentiating the geographical origins of commercial white rice. In this study, we developed a method that employed lipidomics and deep learning to discriminate white rice from Korea to China. A total of 126 white rice of 30 cultivars from different regions were utilized for the method development and validation. By using direct infusion-mass spectrometry-based targeted lipidomics, 17 lysoglycerophospholipids were simultaneously characterized within minutes per sample. Unsupervised data exploration showed a noticeable overlap of white rice between two countries. In addition, lysophosphatidylcholines (lysoPCs) were prominent in white rice from Korea while lysophosphatidylethanolamines (lysoPEs) were enriched in white rice from China. A deep learning prediction model was built using 2014 white rice and validated using two different batches of 2015 white rice. The model accurately discriminated white rice from two countries. Among 10 selected predictors, lysoPC(18:2), lysoPC(14:0), and lysoPE(16:0) were the three most important features. Random forest and gradient boosting machine models also worked well in this circumstance. In conclusion, this study provides an architecture for high-throughput classification of white rice from different geographical origins.

  2. Shareholder Protection and Stock Market Development: An Empirical Test of the Legal Origins Hypothesis

    OpenAIRE

    John Armour; Simon Deakin; Prabirjit Sarkar; Mathias Siems; Ajit Singh

    2008-01-01

    We test the ‘law matters’ and ‘legal origin’claims using a newly created panel dataset measuring legal change over time in a sample of developed and developing countries. Our dataset improves on previous ones by avoiding country-specific variables in favour of functional and generic descriptors, by taking into account a wider range of legal data, and by considering the effects of weighting variables in different ways, thereby ensuring greater consistency of coding....

  3. Origin of inorganic and organic components of PM2.5 in subway stations of Barcelona, Spain.

    Science.gov (United States)

    Martins, Vânia; Moreno, Teresa; Minguillón, María Cruz; van Drooge, Barend L; Reche, Cristina; Amato, Fulvio; de Miguel, Eladio; Capdevila, Marta; Centelles, Sonia; Querol, Xavier

    2016-01-01

    The present work assesses indoor air quality in stations of the Barcelona subway system. PM2.5 concentrations on the platforms of 4 subway stations were measured during two different seasons and the chemical composition was determined. A Positive Matrix Factorization analysis was performed to identify and quantify the contributions of major PM2.5 sources in the subway stations. Mean PM2.5 concentrations varied according to the stations design and seasonal periods. PM2.5 was composed of haematite, carbonaceous aerosol, crustal matter, secondary inorganic compounds, trace elements, insoluble sulphate and halite. Organic compounds such as PAHs, nicotine, levoglucosan and aromatic musk compounds were also identified. Subway PM2.5 source comprised emissions from rails, wheels, catenaries, brake pads and pantographs. The subway source showed different chemical profiles for each station, but was always dominated by Fe. Control actions on the source are important for the achievement of better air quality in the subway environment. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  4. Socioeconomic Status, Ethnicity, Culture, and Immigration: Examining the Potential Mechanisms Underlying Mexican-Origin Adolescents' Organized Activity Participation

    Science.gov (United States)

    Simpkins, Sandra D.; Delgado, Melissa Y.; Price, Chara D.; Quach, Alex; Starbuck, Elizabeth

    2013-01-01

    The integrative model for child development and ecodevelopmental theory suggest that macro factors, such as socioeconomic status, ethnicity, culture, and immigration influence the settings in which adolescents engage. The goal of this investigation was to use a combination of deductive and inductive qualitative analysis to describe the mechanisms…

  5. Evidence of Selection against Complex Mitotic-Origin Aneuploidy during Preimplantation Development

    Science.gov (United States)

    McCoy, Rajiv C.; Demko, Zachary P.; Ryan, Allison; Banjevic, Milena; Hill, Matthew; Sigurjonsson, Styrmir; Rabinowitz, Matthew; Petrov, Dmitri A.

    2015-01-01

    Whole-chromosome imbalances affect over half of early human embryos and are the leading cause of pregnancy loss. While these errors frequently arise in oocyte meiosis, many such whole-chromosome abnormalities affecting cleavage-stage embryos are the result of chromosome missegregation occurring during the initial mitotic cell divisions. The first wave of zygotic genome activation at the 4–8 cell stage results in the arrest of a large proportion of embryos, the vast majority of which contain whole-chromosome abnormalities. Thus, the full spectrum of meiotic and mitotic errors can only be detected by sampling after the initial cell divisions, but prior to this selective filter. Here, we apply 24-chromosome preimplantation genetic screening (PGS) to 28,052 single-cell day-3 blastomere biopsies and 18,387 multi-cell day-5 trophectoderm biopsies from 6,366 in vitro fertilization (IVF) cycles. We precisely characterize the rates and patterns of whole-chromosome abnormalities at each developmental stage and distinguish errors of meiotic and mitotic origin without embryo disaggregation, based on informative chromosomal signatures. We show that mitotic errors frequently involve multiple chromosome losses that are not biased toward maternal or paternal homologs. This outcome is characteristic of spindle abnormalities and chaotic cell division detected in previous studies. In contrast to meiotic errors, our data also show that mitotic errors are not significantly associated with maternal age. PGS patients referred due to previous IVF failure had elevated rates of mitotic error, while patients referred due to recurrent pregnancy loss had elevated rates of meiotic error, controlling for maternal age. These results support the conclusion that mitotic error is the predominant mechanism contributing to pregnancy losses occurring prior to blastocyst formation. This high-resolution view of the full spectrum of whole-chromosome abnormalities affecting early embryos provides insight

  6. Evidence of Selection against Complex Mitotic-Origin Aneuploidy during Preimplantation Development.

    Directory of Open Access Journals (Sweden)

    Rajiv C McCoy

    2015-10-01

    Full Text Available Whole-chromosome imbalances affect over half of early human embryos and are the leading cause of pregnancy loss. While these errors frequently arise in oocyte meiosis, many such whole-chromosome abnormalities affecting cleavage-stage embryos are the result of chromosome missegregation occurring during the initial mitotic cell divisions. The first wave of zygotic genome activation at the 4-8 cell stage results in the arrest of a large proportion of embryos, the vast majority of which contain whole-chromosome abnormalities. Thus, the full spectrum of meiotic and mitotic errors can only be detected by sampling after the initial cell divisions, but prior to this selective filter. Here, we apply 24-chromosome preimplantation genetic screening (PGS to 28,052 single-cell day-3 blastomere biopsies and 18,387 multi-cell day-5 trophectoderm biopsies from 6,366 in vitro fertilization (IVF cycles. We precisely characterize the rates and patterns of whole-chromosome abnormalities at each developmental stage and distinguish errors of meiotic and mitotic origin without embryo disaggregation, based on informative chromosomal signatures. We show that mitotic errors frequently involve multiple chromosome losses that are not biased toward maternal or paternal homologs. This outcome is characteristic of spindle abnormalities and chaotic cell division detected in previous studies. In contrast to meiotic errors, our data also show that mitotic errors are not significantly associated with maternal age. PGS patients referred due to previous IVF failure had elevated rates of mitotic error, while patients referred due to recurrent pregnancy loss had elevated rates of meiotic error, controlling for maternal age. These results support the conclusion that mitotic error is the predominant mechanism contributing to pregnancy losses occurring prior to blastocyst formation. This high-resolution view of the full spectrum of whole-chromosome abnormalities affecting early embryos

  7. an appraisal of training and development in organizations in nigeria

    African Journals Online (AJOL)

    Organization is a formalized intentional structure of roles or positions (Weihrich and. Koontz, 2006). Growth in .... Prepare the Training Programme Based on the skill analysis, the subjects to be taught, the ... materials, machines or equipments.

  8. Developing and Organizing a Trauma System and Mass Casualty ...

    African Journals Online (AJOL)

    An effective trauma system may potentially manage mass casualty incidence ... Israel has a unique trauma system of organizing and managing an emergency event, ... Wisdom, motivation and pragmatism of the Israeli model may be useful to ...

  9. Developing a Matrix Organization to Unify Learning Support Services.

    Science.gov (United States)

    Clarke, John H.; Mansfield, Barry K.

    1988-01-01

    Describes use of matrix management to organize learning support services on a college campus. Claims matrix management, which links support services from academic and student affairs, increases access, improves accountability, and encourages new programs. (Author/ABL)

  10. 36 Problems and Prospect of Organic Farming in Developing ...

    African Journals Online (AJOL)

    Choice-Academy

    area of soil nutrient restoration to encourage the use of organic materials, termed ... and social sustainability in its approach ... It improves the physical, chemical ... response to applied fertilizer depends on ..... Society of Agricultural Engineer.

  11. Contemporary organization and a perspective on integration and development

    OpenAIRE

    Anna Piekarczyk

    2015-01-01

    A contemporary organization is becoming more and more complex and dynamic. Managing such an organization often requires new solutions in order to face the fast-expanding comprehensiveness in economy, politics and private life. Understanding complex connections between the elements of a system can remedy this situation. Therefore, when planning and making decisions a lot of factors should be taken into consideration and their interdependencies should be seen. Know-why methodology, thanks to wh...

  12. The development of organic farming in the world

    Directory of Open Access Journals (Sweden)

    KOMOROWSKA Dorota

    2015-12-01

    Full Text Available The article aims to present the size of organic farming and organic food market in each region of the world based on available statistics. The largest area of agricultural land farmed using organic methods is located in Australia, Europe and South America, while the biggest organic food markets are located in the rich countries of North America, mainly in the United States, and in the Western European countries. Fruits and vegetables are the organic products that are the most eagerly bought and dominate the organic food market. Rezumat. Articolul îşi propune să prezinte dimensiunea agriculturii ecologice şi a pieţei produselor alimentare ecologice în fiecare regiune a lumii în baza datelor statistice disponibile. Cea mai mare suprafaţă de teren agricol cultivat folosind metode organice se află în Australia, Europa şi America de Sud, în timp ce cele mai mari pieţe de produse alimentare ecologice sunt situate în ţările bogate din America de Nord, în special în Statele Unite ale Americii, precum şi în ţările din Europa de Vest. Fructele şi legumele sunt produsele organice care se vând cel mai bine şi care domină piaţa produselor alimentare ecologice.

  13. The origin of soil organic matter controls its composition and bioreactivity across a mesic boreal forest latitudinal gradient

    Science.gov (United States)

    Kohl, L.; Philben, M. J.; Edwards, K. A.; Podrebarac, F. A.; Jamie, W.; Ziegler, S. E.

    2017-12-01

    Warmer climates have been associated with reduced soil organic matter (SOM) bioreactivity, lower respiration rates at a given temperature, which is typically attributed to the presence of more decomposed SOM. Cross site studies, however, indicate that ecosystem regime shifts associated with long-term climate warming can affect SOM properties through changes in vegetation and plant litter inputs to soils. The relative importance of these two controls, diagenesis and inputs, on SOM properties as ecosystems experience climate warming remains poorly understood. To address this, we characterized the elemental, chemical (nuclear magnetic resonance spectroscopy and total hydrolysable amino acids), and isotopic composition of plant litter and SOM across a well-constrained mesic boreal forest latitudinal transect in Atlantic Canada. Results across forest sites within each of three climate regions indicated that (1) climate history and diagenesis affect distinct parameters of SOM chemistry, (2) increases in SOM bioreactivity with latitude were associated with elevated proportions of carbohydrates relative to plant waxes and lignin, and (3) despite the common forest type across regions, differences in SOM chemistry by climate region were associated with chemically distinct litter inputs and not different degrees of diagenesis. Climate effects on vascular plant litter chemistry explained only part of the regional differences in SOM chemistry, most notably the higher protein content of SOM from warmer regions. Greater proportions of lignin and aliphatic compounds and smaller proportions of carbohydrates in warmer sites' soils were explained by the higher proportion of vascular plant relative to moss litter in the warmer forests. These results indicate that a climate induced decrease in the proportion of moss inputs will not only impact SOM chemistry but also increase the resistance of SOM to decomposition, thus significantly altering SOM cycling in these boreal forest soils.

  14. The early origins of food preferences: targeting the critical windows of development.

    Science.gov (United States)

    Gugusheff, Jessica Rose; Ong, Zhi Yi; Muhlhausler, Beverly Sara

    2015-02-01

    The nutritional environment to which an individual is exposed during the perinatal period plays a crucial role in determining his or her future metabolic health outcomes. Studies in rodent models have demonstrated that excess maternal intake of high-fat and/or high-sugar "junk foods" during pregnancy and lactation can alter the development of the central reward pathway, particularly the opioid and dopamine systems, and program an increased preference for junk foods in the offspring. More recently, there have been attempts to define the critical windows of development during which the opioid and dopamine systems within the reward pathway are most susceptible to alteration and to determine whether it is possible to reverse these effects through nutritional interventions applied later in development. This review discusses the progress made to date in these areas, highlights the apparent importance of sex in determining these effects, and considers the potential implications of the findings from rodent models in the human context. © FASEB.

  15. Do organizations spend wisely on employees? Effects of training and development investments on learning and innovation in organizations.

    Science.gov (United States)

    Sung, Sun Young; Choi, Jin Nam

    2014-04-01

    The present study examines the effects of training and development on organizational innovation. We specifically suggest that the training and development investments of an organization affect its innovative performance by promoting various learning practices. We empirically tested our hypothesis by using time-lagged, multi-source data collected from 260 Korean companies that represent diverse industries. Our analysis showed that corporate expenditure for internal training predicts interpersonal and organizational learning practices, which, in turn, increase innovative performance. The data also revealed that the positive relationship between interpersonal and organizational learning practices and innovative performance is stronger within organizations that have stronger innovative climates. By contrast, investment in employee development through financial support for education outside an organization poses a significant negative effect on its innovative performance and no significant effect on learning practices. The present study provides a plausible explanation for a mechanism through which the investment of an organization in employees enhances its innovative performance. Copyright © 2013 The Authors.

  16. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    Practices: Universities in. Faculty of Education and Behavioral Sci ... adequate experience concerning problem-solving teach shows that teachers possess the theories and their a organizing ... Behavioral Science, Bahir Dar University, Bahir Dar, Ethiopia. Abstract ...... Educational Leadership 42(7): 57-60. Haney, J.J. ...

  17. Original Research Original Research

    African Journals Online (AJOL)

    User

    2013-06-26

    Jun 26, 2013 ... ost all the organizations in performing their business. The ... ital role in a company's wad and ..... perceived risk of failure, complexity, security, and .... model of technology-based selfservice: moderating ... strategic distribution channel decisions, International ... Managerial Auditing Journal 14(7): 329-338.

  18. Original Research Original Research

    African Journals Online (AJOL)

    User

    Organics must form an indispensable component o any crop. The present study was designed to stud. (BD) compost on biochemical parameters of soya be and 75th day after sowing. The protein content was m of BD compost) on 30th, 45th, 60th and 75 found to be maximum in T1 (3.5 kg of BD compost) day.

  19. Ethnic Socialization in Neighborhood Contexts: Implications for Ethnic Attitude and Identity Development Among Mexican-Origin Adolescents.

    Science.gov (United States)

    White, Rebecca M B; Knight, George P; Jensen, Michaeline; Gonzales, Nancy A

    2018-05-01

    Neighborhood Latino ethnic concentration, above and beyond or in combination with mothers' and fathers' ethnic socialization, may have beneficial implications for minority adolescents' ethnic attitude and identity development. These hypotheses, along with two competing hypotheses, were tested prospectively (from x¯age = 12.79-15.83 years) in a sample of 733 Mexican-origin adolescents. Neighborhood ethnic concentration had beneficial implications for ethnic identity processes (i.e., ethnic exploration and perceived peer discrimination) but not for ethnic attitudes. For Mexico-born adolescents, high maternal ethnic socialization compensated for living in neighborhoods low on ethnic concentration. Findings are discussed vis-à-vis the ways in which they address major gaps in the neighborhood effects literature and the ethnic and racial identity development literature. © 2017 The Authors. Child Development © 2017 Society for Research in Child Development, Inc.

  20. Origin and dynamics of oligodendrocytes in the developing brain : Implications for perinatal white matter injury

    NARCIS (Netherlands)

    van Tilborg, Erik; de Theije, Caroline G.M.; van Hal, Maurik; Wagenaar, Nienke; de Vries, Linda S.; Benders, Manon J.; Rowitch, David H; Nijboer, Cora H.

    2018-01-01

    Infants born prematurely are at high risk to develop white matter injury (WMI), due to exposure to hypoxic and/or inflammatory insults. Such perinatal insults negatively impact the maturation of oligodendrocytes (OLs), thereby causing deficits in myelination. To elucidate the precise pathophysiology

  1. Accreditation in the USA: Origins, Developments and Future Prospects. Improving the Managerial Effectiveness of Higher Education.

    Science.gov (United States)

    El-Khawas, Elaine

    This study analyzes the accreditation experience in the United States with special emphasis on the issues and decisions that surrounded the development of evaluation procedures and standards. Attention is given to the relationship between accrediting agencies and governmental agencies, the effect of accrediting requirements on the way that…

  2. A 200 year sedimentary record of progressive eutrophication in lake Greifen (Switzerland): Implications for the origin of organic-carbon-rich sediments

    Science.gov (United States)

    Hollander, David J.; McKenzie, Judith A.; Lo Ten Haven, H.

    1992-09-01

    Over the past 200 years Lake Greifen, a small lake in northeastern Switzerland, has undergone dramatic changes in primary productivity and eutrophication due to increased nutrient supply from agricultural activity and industrialization. A 40 year historical record of the water-column chemistry indicates that productivity and eutrophication reached a maximum in 1974, after which stricter regulations on the input of nutrients resulted in a progressive decrease. Collected cores show the sedimentary expression of this anthropogenically induced eutrophication by a well-developed annual sedimentation and by enhanced values of total organic carbon, organic-carbon accumulation rates, and hydrogen indices (HI) of the kerogens. Analyses of the carbon isotopic composition of sedimentary carbonates and organic matter reveal that the fractionation between these two phases varies with the HI of kerogens. This observation is explicable in terms of changing productivity and preservation of the organic matter, and the CO2(aq) budget of the water body. We propose that if high primary productivity were primarily responsible for the preservation and accumulation of organic matter, then a negative correlation will occur between Δδ13Ccalcite-organic matter (Δδ13Ccal-om) and HI values. In an environment with relatively low to moderate productivity but with bottom-water anoxia, a positive correlation will exist between Δδ13Ccal-om and HI values. This study of Lake Greifen has implications for understanding paleoenvironmental controls on ancient organic-carbon-rich sediments.

  3. Molecular mechanisms controlling brain development: an overview of neuroepithelial secondary organizers.

    Science.gov (United States)

    Vieira, Claudia; Pombero, Ana; García-Lopez, Raquel; Gimeno, Lourdes; Echevarria, Diego; Martínez, Salvador

    2010-01-01

    The vertebrate Central Nervous System (CNS) originates from the embryonic dorsal ectoderm. Differentiation of the neural epithelium from the ectoderm and the formation of the neural plate constitute the first phase of a complex process called neurulation which culminates in the formation of the neural tube, the anlage of the CNS in sauropsids and mammals (for review see Smith and Schoenwolf, 1997; Colas and Schoenwolf, 2001). At neural plate and neural tube stages, local signaling centers in the neuroepithelium, known as secondary organizers, refine the antero-posterior specification of different neural territories (for review see Echevarria et al., 2003; Stern et al.,2006; Woltering and Durston, 2008). In this review, we will describe the principle aspects of CNS development in birds and mammals, starting from early stages of embryogenesis (gastrulation and neurulation) and culminating with the formation of a variety of different regions which contribute to the structural complexity of the brain (regionalization and morphogenesis). We will pay special attention to the cellular and molecular mechanisms involved in neural tube regionalization and the key role played by localized secondary organizers in the patterning of neural primordia.

  4. Germ layers, the neural crest and emergent organization in development and evolution.

    Science.gov (United States)

    Hall, Brian K

    2018-04-10

    Discovered in chick embryos by Wilhelm His in 1868 and named the neural crest by Arthur Milnes Marshall in 1879, the neural crest cells that arise from the neural folds have since been shown to differentiate into almost two dozen vertebrate cell types and to have played major roles in the evolution of such vertebrate features as bone, jaws, teeth, visceral (pharyngeal) arches, and sense organs. I discuss the discovery that ectodermal neural crest gave rise to mesenchyme and the controversy generated by that finding; the germ layer theory maintained that only mesoderm could give rise to mesenchyme. A second topic of discussion is germ layers (including the neural crest) as emergent levels of organization in animal development and evolution that facilitated major developmental and evolutionary change. The third topic is gene networks, gene co-option, and the evolution of gene-signaling pathways as key to developmental and evolutionary transitions associated with the origin and evolution of the neural crest and neural crest cells. © 2018 Wiley Periodicals, Inc.

  5. Deuterium enrichments in chondritic macromolecular material—Implications for the origin and evolution of organics, water and asteroids

    Science.gov (United States)

    Alexander, C. M. O.'D.; Newsome, S. D.; Fogel, M. L.; Nittler, L. R.; Busemann, H.; Cody, G. D.

    2010-08-01

    Here we report the elemental and isotopic compositions of the insoluble organic material (IOM) isolated from several previously unanalyzed meteorites, as well as the reanalyses of H isotopic compositions of some previously measured samples ( Alexander et al., 2007). The IOM in ordinary chondrites (OCs) has very large D enrichments that increase with increasing metamorphism and decreasing H/C, the most extreme δD value measured being almost 12,000‰. We propose that such large isotopic fractionations could be produced in the OC parent bodies through the loss of isotopically very light H 2 generated when Fe was oxidized by water at low temperatures (IOM of CV and CO chondrites with similar metamorphic grades and IOM H/C ratios because proportionately less water was consumed during metamorphism, and the remaining water buffered the H isotopic composition of the IOM even a H was being lost from it. Hydrogen would also have been generated during the alteration of CI, CM and CR carbonaceous chondrites. The IOM in these meteorites exhibit a considerable range in isotopic compositions, but all are enriched in D, as well as 15N, relative to terrestrial values. We explore whether these enrichments could also have been produced by the loss of H 2, but conclude that the most isotopically anomalous IOM compositions in meteorites from these groups are probably closest to their primordial values. The less isotopically anomalous IOM has probably been modified by parent body processes. The response of IOM to these processes was complex and varied, presumably reflecting differences in conditions within and between parent bodies. The D enrichments associated with H 2 generation, along with exchange between D-rich IOM and water in the parent bodies, means that it is unlikely that any chondrites retain the primordial H isotopic composition of the water ice that they accreted. The H isotopic compositions of the most water-rich chondrites, the CMs and CIs, are probably the least

  6. Geochemical characterization of the Jurassic Amran deposits from Sharab area (SW Yemen): Origin of organic matter, paleoenvironmental and paleoclimate conditions during deposition

    Science.gov (United States)

    Hakimi, Mohammed Hail; Abdullah, Wan Hasiah; Makeen, Yousif M.; Saeed, Shadi A.; Al-Hakame, Hitham; Al-Moliki, Tareq; Al-Sharabi, Kholah Qaid; Hatem, Baleid Ali

    2017-05-01

    is attributed to the thermal effect on the original organic matter. This high thermal maturity level is due to the presence of volcanic rocks, which have invaded the Jurassic rocks during Late Oligocene to Early Miocene.

  7. The development of artificial organs and prostheses worldwide and in the Ottoman Empire.

    Science.gov (United States)

    Birdane, Leman; Cingi, Cemal; Elçioğlu, Ömür; Muluk, Nuray Bayar

    2016-08-01

    An artificial organ or prosthesis is a man-made device that is implanted or integrated into a human to replace a natural organ. There were many historical steps in the development of artificial organs and prostheses. New surgical techniques, the development of prosthetic materials and the creative ideas of engineers led to progress in this field. © The European Society of Cardiology 2014.

  8. [Management of military medical service in Ukraine: origin, trends, and mechanism of development (1992-2004)].

    Science.gov (United States)

    Radysh, Ia F

    2005-01-01

    Three periods of the development of military medical service management in Ukraine can be outlined according to the findings of the conducted study, they are the following: formation (1992-1994), consolidation and development (the end of 1994-2003), functional and structural transformation (2004). Leading tendencies of the formation of the management of medical military service in the period are shown in the article to be democratization and structural order of units of the system of the management of military service, integration of efforts and resources of medical military service in one medically covered area of the state, introduction and intensive expansion in army prophylactic and treatment institutions of wide spectrum of requiring payment medical service, rendering out-patient medical service to armed forces personnel and pensioner of Ministry of Defense by family physicians, orientation toward effective management.

  9. Changes of the agricultural enterprises economic environment originated by the agribusiness development

    Directory of Open Access Journals (Sweden)

    Věra Bečvářová

    2004-01-01

    Full Text Available Based upon analyses of the Common Agricultural Policy development and its economic tools reforming the process of changing is characterised there. It deals with the multifunctionality of agriculture as well as the influence of the CAP on environment of the production tasks of agriculture and food processing industry accomplishment. Paper generalises results of new trends of the agribusiness economic environment development and the opportunity of an effective utilization of production factors in agriculture. It deals with the sources and economic implications of partial enhancement of interest and redirection of support within framework and type of tools of agrarian policy. New quality of structure of relevant information needs and economic support for agricultural enterprises decision making process are pointed out.

  10. NASA Astrophysics Cosmic Origins (COR) and Physics of the Cosmos (PCOS) Strategic Technology Development Program

    Science.gov (United States)

    Pham, Thai; Seery, Bernard D.

    2015-01-01

    The COR and PCOS Program Offices (PO) reside at the NASA Goddard Space Flight Center (GSFC), serving as the NASA Astrophysics Division's implementation arm for matters relating to the two programs. One aspect of the PO's activities is managing the COR and PCOS Strategic Astrophysics Technology (SAT) program, helping mature technologies to enable and enhance future astrophysics missions.The PO is guided by the National Research Council's 'New Worlds, New Horizons in Astronomy and Astrophysics' Decadal Survey report, and NASA's Astrophysics Implementation Plan. Strategic goals include dark energy; gravitational waves; X-ray observatories, e.g., US participation in ATHENA; Inflation probe; and a large UV/Visible telescope.To date, 51 COR and 65 PCOS SAT proposals have been received, of which 11 COR and 18 PCOS projects were funded. Notable successes include maturation of a new far-IR detector, later adopted by the SOFIA HAWC instrument; maturation of the H4RG near-IR detector, adopted by WFIRST; development of an antenna-coupled transition-edge superconducting bolometer, a technology deployed by BICEP2 that allowed measurement of B-mode polarization in the CMB signal, a possible signature of Inflation; and finally, the REXIS instrument on OSIRIS-REx is incorporating CCDs with directly deposited optical blocking filters developed by another SAT-funded project.We discuss our technology development process, with community input and strategic prioritization informing calls for SAT proposals and guiding investment decisions. We also present results of this year's technology gap prioritization and showcase our current portfolio of technology development projects. These include five newly selected projects, kicking off in FY 2015.For more information, visit the COR Program website at cor.gsfc.nasa.gov and the PCOS website at pcos.gsfc.nasa.gov.

  11. Origin and development of plasma membrane derived invaginations in Vinca rosea l.

    Science.gov (United States)

    Mahlberg, P.; Walkinshaw, C.; Olson, K.

    1971-01-01

    The occurrence, morphology, and possible ontogeny of plasma-membrane-related structures are described which can develop into invaginations or intravacuolar formations. An underlying study of meristematic tissues from the shoot of Vinca rosea supports the interpretation that endocytosis does occur in plant cells and that it is appropriate to refer to these structures as endocytoses. The function of these invaginations or their content remains to be elucidated.

  12. Origin of the Substitution Mechanism for the Binding of Organic Ligands on the Surface of CsPbBr3 Perovskite Nanocubes.

    Science.gov (United States)

    Ravi, Vikash Kumar; Santra, Pralay K; Joshi, Niharika; Chugh, Jeetender; Singh, Sachin Kumar; Rensmo, Håkan; Ghosh, Prasenjit; Nag, Angshuman

    2017-10-19

    Optoelectronic properties of CsPbBr 3 perovskite nanocubes (NCs) depend strongly on the interaction of the organic passivating molecules with the inorganic crystal. To understand this interaction, we employed a combination of synchrotron-based X-ray photoelectron spectroscopy (XPS), nuclear magnetic resonance (NMR) spectroscopy, and first-principles density functional theory (DFT)-based calculations. Variable energy XPS elucidated the internal structure of the inorganic part in a layer-by-layer fashion, whereas NMR characterized the organic ligands. Our experimental results confirm that oleylammonium ions act as capping ligands by substituting Cs + ions from the surface of CsPbBr 3 NCs. DFT calculations shows that the substitution mechanism does not require much energy for surface reconstruction and, in contrast, stabilizes the nanocrystal by the formation of three hydrogen bonds between the -NH 3 + moiety of oleylammonium and surrounding Br - on the surface of NCs. This substitution mechanism and its origin are in stark contrast to the usual adsorption of organic ligands on the surface of typical NCs.

  13. The origin of soil organic matter dictates its composition and bioreactivity across a mesic boreal forest latitudinal gradient

    Science.gov (United States)

    Kohl, Lukas; Philben, Michael; Edwards, Kate A.; Podrebarac, Frances A.; Warren, Jamie; Ziegler, Susan E.

    2017-04-01

    Climate transect studies and soil warming experiments have shown that soil organic matter (SOM) formed under a warmer climate is typically more resistant to microbial decomposition, as indicated by lower decomposition rates at a given temperature (bioreactivity). However, it remains unclear how climate impacts SOM via its effect on vegetation and thus litter inputs to soils, or on decomposition and thus how SOM changes over time (diagenesis). We addressed this question by studying how the chemical and biological properties of SOM vary with decomposition (depth) and climate history (latitude) in mesic boreal forests of Atlantic Canada. SOM bioreactivity, measured in a 15-months decomposition experiment, decreased from cold to warm regions, and from the topmost (L) to the deepest horizon studied (H). The variations in SOM bioreactivity with climate history and depth, however, were associated with distinct parameters of SOM chemistry. More decomposed SOM with depth was associated with lower proportions of %N as total hydrolysable amino acids (THAA), and a different THAA-based degradation index signifying a more degraded state. However, SOM from the warmer region exhibited higher lignin to carbohydrate ratios, as detected by NMR. None of the measured parameters associated with regional differences in SOM chemistry increased with depth. Together, these results indicate that the regional differences in SOM chemistry and bioreactivity in these soils did not result from significant differences in the degree of degradation, but rather resulted from chemically distinct litter inputs. The comparison of SOM and plant litter chemistry allowed us to identify how climate affects litter inputs in these forests. Vascular plant litter collected in litter traps, unlike SOM, exhibited largely similar chemical composition across all transect regions. Litter traps, however, do not collect moss litter, which is chemically distinct from vascular plant litter. We, therefore, assessed the

  14. Therapeutic Potential and Pharmaceutical Development of Thymoquinone: A Multitargeted Molecule of Natural Origin

    Directory of Open Access Journals (Sweden)

    Sameer N. Goyal

    2017-09-01

    Full Text Available Thymoquinone, a monoterpene molecule is chemically known as 2-methyl-5-isopropyl-1, 4-benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known as black cumin or black seed and belongs to the family Ranunculaceae. A large number of studies have revealed that thymoquinone is the major active constituent in N. sativa oil this constituent is responsible for the majority of the pharmacological properties. The beneficial organoprotective activities of thymoquinone in experimental animal models of different human diseases are attributed to the potent anti-oxidant and anti-inflammatory properties. Thymoquinone has also been shown to alter numerous molecular and signaling pathways in many inflammatory and degenerative diseases including cancer. Thymoquinone has been reported to possess potent lipophilicity and limited bioavailability and exhibits light and heat sensitivity. Altogether, these physiochemical properties encumber the successful formulation for the delivery of drug in oral dosages form and restrict the pharmaceutical development. In recent past, many efforts were undertaken to improve the bioavailability for clinical usage by manipulating the physiochemical parameters. The present review aimed to provide insights regarding the physicochemical characteristics, pharmacokinetics and the methods to promote pharmaceutical development and endorse the clinical usage of TQ in future by overcoming the associated physiochemical obstacles. It also enumerates briefly the pharmacological and molecular targets of thymoquinone as well as the pharmacological properties in various diseases and the underlying molecular mechanism. Though, a convincing number of experimental studies are available but human studies are not available with thymoquinone despite of the long history of use of black cumin in different diseases. Thus, the clinical studies including pharmacokinetic studies and regulatory toxicity studies are required

  15. Therapeutic Potential and Pharmaceutical Development of Thymoquinone: A Multitargeted Molecule of Natural Origin.

    Science.gov (United States)

    Goyal, Sameer N; Prajapati, Chaitali P; Gore, Prashant R; Patil, Chandragouda R; Mahajan, Umesh B; Sharma, Charu; Talla, Sandhya P; Ojha, Shreesh K

    2017-01-01

    Thymoquinone, a monoterpene molecule is chemically known as 2-methyl-5-isopropyl-1, 4-benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known as black cumin or black seed and belongs to the family Ranunculaceae . A large number of studies have revealed that thymoquinone is the major active constituent in N. sativa oil this constituent is responsible for the majority of the pharmacological properties. The beneficial organoprotective activities of thymoquinone in experimental animal models of different human diseases are attributed to the potent anti-oxidant and anti-inflammatory properties. Thymoquinone has also been shown to alter numerous molecular and signaling pathways in many inflammatory and degenerative diseases including cancer. Thymoquinone has been reported to possess potent lipophilicity and limited bioavailability and exhibits light and heat sensitivity. Altogether, these physiochemical properties encumber the successful formulation for the delivery of drug in oral dosages form and restrict the pharmaceutical development. In recent past, many efforts were undertaken to improve the bioavailability for clinical usage by manipulating the physiochemical parameters. The present review aimed to provide insights regarding the physicochemical characteristics, pharmacokinetics and the methods to promote pharmaceutical development and endorse the clinical usage of TQ in future by overcoming the associated physiochemical obstacles. It also enumerates briefly the pharmacological and molecular targets of thymoquinone as well as the pharmacological properties in various diseases and the underlying molecular mechanism. Though, a convincing number of experimental studies are available but human studies are not available with thymoquinone despite of the long history of use of black cumin in different diseases. Thus, the clinical studies including pharmacokinetic studies and regulatory toxicity studies are required to encourage the

  16. Development and tuning of an original search engine for patent libraries in medicinal chemistry.

    Science.gov (United States)

    Pasche, Emilie; Gobeill, Julien; Kreim, Olivier; Oezdemir-Zaech, Fatma; Vachon, Therese; Lovis, Christian; Ruch, Patrick

    2014-01-01

    The large increase in the size of patent collections has led to the need of efficient search strategies. But the development of advanced text-mining applications dedicated to patents of the biomedical field remains rare, in particular to address the needs of the pharmaceutical & biotech industry, which intensively uses patent libraries for competitive intelligence and drug development. We describe here the development of an advanced retrieval engine to search information in patent collections in the field of medicinal chemistry. We investigate and combine different strategies and evaluate their respective impact on the performance of the search engine applied to various search tasks, which covers the putatively most frequent search behaviours of intellectual property officers in medical chemistry: 1) a prior art search task; 2) a technical survey task; and 3) a variant of the technical survey task, sometimes called known-item search task, where a single patent is targeted. The optimal tuning of our engine resulted in a top-precision of 6.76% for the prior art search task, 23.28% for the technical survey task and 46.02% for the variant of the technical survey task. We observed that co-citation boosting was an appropriate strategy to improve prior art search tasks, while IPC classification of queries was improving retrieval effectiveness for technical survey tasks. Surprisingly, the use of the full body of the patent was always detrimental for search effectiveness. It was also observed that normalizing biomedical entities using curated dictionaries had simply no impact on the search tasks we evaluate. The search engine was finally implemented as a web-application within Novartis Pharma. The application is briefly described in the report. We have presented the development of a search engine dedicated to patent search, based on state of the art methods applied to patent corpora. We have shown that a proper tuning of the system to adapt to the various search tasks

  17. [The origin and development of fragrance activity in Chinese ancient times].

    Science.gov (United States)

    Ding, Jie-yun; Jin, Zhi-jun

    2010-05-01

    It has a long history of the fragrance activities in the ancient China. During the period of pre-Qin, it was mainly used in the therapy and worship. Until the Three Kingdoms, the crowd using the fragrance expanded from the royal to the literati and the general officials. People applied the spices to incense clothes, purify rooms, prevent and treat epidemic diseases in daily. In the worship, the spices were dedicated to Gods and other fairies. The fragrance was developed quickly during the period from Wei Dynasty to South and North Dynasties. People had more experiences of spices used as medicines, the formula of spices were used more widely. Then, during the period from Sui Dynasty to Song Dynasty, the fragrance activities climbed to the peak. The fragrance activities were institutionalized, when nobility matched their spices each other. The Literati made spice products and enjoyed the fragrance activities. Doctors knew more than before in the application experiences and species of spices. In the times of Yuan, Ming and Qing Dynasty, the fragrance activities spread among the public. The spices appeared in each side of the daily life of nobility, when natural fruits appeared in the fragrance activities. External therapy with spices appeared in the clinical. In addition to prevention and therapy, spices should be used in the embalming. After a long period, the fragrance activities had gradually developed into a kind of culture.

  18. [Elementary exploration of the origin and development of marine Chinese materia medica].

    Science.gov (United States)

    Guan, Hua-Shi; Fu, Xian-Jun; Wu, Qiang-Ming; Wang, Chang-Yun; Wang, Yu; Jiang, Deng-Zhao

    2009-05-01

    According to archaeological discoveries, humans began to make use of marine natural resources early in the Palaeolithic era. In the Spring and Autumn period and Warring States period, they began to use marine life as medicines and also had simple cognitions on their efficacy and processing. In the Qin and Han dynasties, people further deepened the understanding of the marine Chinese materia medica and created prescriptions making use of marine drugs. In the Tang and Song period, the number of marine Chinese materia medica species and corresponding prescriptions apparently increased. The cognitions of the property, flavor, efficacy as well as the compatible principle of marine Chinese materia medica was further deepened and the scope of their treatment also significantly expanded. In the Ming and Qing dynasties, the cognition of the marine Chinese materia medica was mainly the conclusions of the previous experience. After the founding of the People's Republic of China (PRC), with the development of science and technologies, the ability of exploiting and utilizing the marine Chinese materia medica by people dramatically increased, and the species of marine Chinese materia medica reached more than one thousand. However, the development of marine Chinese materia medica is confronted with new problems; although the number of species of marine Chinese materia medica increased, the understanding of their property and flavor is obviously lagging behind, which seriously affects the clinical application of marine Chinese materia medica.

  19. Aegilops tauschii Accessions with Geographically Diverse Origin Show Differences in Chromosome Organization and Polymorphism of Molecular Markers Linked to Leaf Rust and Powdery Mildew Resistance Genes.

    Science.gov (United States)

    Majka, Maciej; Kwiatek, Michał T; Majka, Joanna; Wiśniewska, Halina

    2017-01-01

    Aegilops tauschii (2n = 2x = 14) is a diploid wild species which is reported as a donor of the D-genome of cultivated bread wheat. The main goal of this study was to examine the differences and similarities in chromosomes organization among accessions of Ae. tauschii with geographically diversed origin, which is believed as a potential source of genes, especially determining resistance to fungal diseases (i.e., leaf rust and powdery mildew) for breeding of cereals. We established and compared the fluorescence in situ hybridization patterns of 21 accessions of Ae. tauschii using various repetitive sequences mainly from the BAC library of wheat cultivar Chinese Spring. Results obtained for Ae. tauschii chromosomes revealed many similarities between analyzed accessions, however, some hybridization patterns were specific for accessions, which become from cognate regions of the World. The most noticeable differences were observed for accessions from China which were characterized by presence of distinct signals of pTa-535 in the interstitial region of chromosome 3D, less intensity of pTa-86 signals in chromosome 2D, as well as lack of additional signals of pTa-86 in chromosomes 1D, 5D, or 6D. Ae. tauschii of Chinese origin appeared homogeneous and separate from landraces that originated in western Asia. Ae. tauschii chromosomes showed similar hybridization patterns to wheat D-genome chromosomes, but some differences were also observed among both species. What is more, we identified reciprocal translocation between short arm of chromosome 1D and long arm of chromosome 7D in accession with Iranian origin. High polymorphism between analyzed accessions and extensive allelic variation were revealed using molecular markers associated with resistance genes. Majority of the markers localized in chromosomes 1D and 2D showed the diversity of banding patterns between accessions. Obtained results imply, that there is a moderate or high level of polymorphism in the genome of Ae

  20. The origin and historical development of branding and advertising in the old civilizations of Africa, Asia and Europe

    Directory of Open Access Journals (Sweden)

    Starčević Slađana

    2015-01-01

    Full Text Available The development of branding and advertising has always been mutually conditioned. The goal of this research is to determine the origin and show historic development of branding and advertising in the ancient civilizations of Africa, Asia and Europe. The historical method of research was used. New evidence on various means of branding, advertising and other promotional activities application in the ancient history is presented. What was found is that social development imposed a need for marking of goods and promotional activities. It was done in a similar manner in all ancient civilizations, regardless of different time span. There were two types of branding and advertising: commercial and personal. The roles of branding and advertising were versatile and similar to their contemporary roles.

  1. Proceedings of the Workshop on Recent Developments in Organic NMR

    International Nuclear Information System (INIS)

    1986-01-01

    Some works about application of nuclear magnetic resonance in several aspects are presented. Some structures of effects caused by organic materials in the solid state are shown. The nuclear magnetic resonance characterization in different types of products and determinations of molecular structures are studied. (M.J.C.) [pt

  2. The Canadian Healthy Infant Longitudinal Development (CHILD) Study: examining developmental origins of allergy and asthma.

    Science.gov (United States)

    Subbarao, Padmaja; Anand, Sonia S; Becker, Allan B; Befus, A Dean; Brauer, Michael; Brook, Jeffrey R; Denburg, Judah A; HayGlass, Kent T; Kobor, Michael S; Kollmann, Tobias R; Kozyrskyj, Anita L; Lou, W Y Wendy; Mandhane, Piushkumar J; Miller, Gregory E; Moraes, Theo J; Pare, Peter D; Scott, James A; Takaro, Tim K; Turvey, Stuart E; Duncan, Joanne M; Lefebvre, Diana L; Sears, Malcolm R

    2015-10-01

    The Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort study recruited 3624 pregnant women, most partners and 3542 eligible offspring. We hypothesise that early life physical and psychosocial environments, immunological, physiological, nutritional, hormonal and metabolic influences interact with genetics influencing allergic diseases, including asthma. Environmental and biological sampling, innate and adaptive immune responses, gene expression, DNA methylation, gut microbiome and nutrition studies complement repeated environmental and clinical assessments to age 5. This rich data set, linking prenatal and postnatal environments, diverse biological samples and rigorous phenotyping, will inform early developmental pathways to allergy, asthma and other chronic inflammatory diseases. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  3. Original Article

    African Journals Online (AJOL)

    regression analysis showed that the development of postoperative multi-organ failure ... stage renal disease (ESRD) requiring renal replacement therapy, has been found to be a ..... 1998;65(3):879-84. Table 3: Binary logistic regression analysis for factors determining early mortality after cardiac surgery (n=500). Factor. OR.

  4. ORIGINAL ARTICLE

    African Journals Online (AJOL)

    User

    This associa- tion has been suggested to be due to the close ana- tomical relationship of the retina and cochlea which develops from the same embryonic layer (Abah et al.,. 2011). Of all the sense organs, visual and auditory inputs are responsible for 95% of information acqui- sition (Fillman et al., 1987). It is also generally.

  5. Origin and development of the new U-Mo nuclear fuel

    International Nuclear Information System (INIS)

    Boyard, M.; Languille, A.; Thomasson, J.; Hamy, J.M.

    2002-01-01

    Historically most research reactors have used highly enriched nuclear fuels (enrichment > 90 %). Since 1977 the non-proliferation policy has imposed to convert these reactors to far less enriched fuels (< 20 %). An international consensus has evolved towards a nuclear fuel with an enrichment factor of 19,75 %, this fuel is made of a powdered U-Mo alloy scattered in an aluminium die. The external dimensions and the cladding materials of the fuel plate are unchanged in order to minimize development and qualification costs. The U-Mo fuel is expected to maintain or even to increase the performance of reactors and to allow the processing of spent fuels in the same installations as those used for fuels issuing from power plants. Cea, Cogema, Cerca, Framatome, and Technicatome have shared their technical means, their know-how and their financial resources to develop this new nuclear fuel. 2006 is the contract date by which American authorities will stop repatriating the ancient spent fuel (uranium silicide) from research reactors so it is imperative to make available by this date a new nuclear fuel with a satisfactory end of cycle. This article also presents the French program of qualification of the U-Mo fuel. 2 series of irradiation have already been performed, one (Isis-1) in Osiris reactor (Saclay, France) and the second (Umus) in HFR (Petten, Netherlands). A clad failure has led to stop the Umus experiment. 2 new series of irradiation are scheduled to start in 2002. In a parallel way, in the framework of the design of the RJH (Jules Horowitz reactor) Cea will soon perform irradiation of U-Mo fuel plates in BR2 (Mol, Belgium). (A.C.)

  6. Principles for interactions with biopharmaceutical companies: the development of guidelines for patient advocacy organizations in the field of rare diseases.

    Science.gov (United States)

    Stein, Susan; Bogard, Elizabeth; Boice, Nicole; Fernandez, Vivian; Field, Tessa; Gilstrap, Alan; Kahn, Susan R; Larkindale, Jane; Mathieson, Toni

    2018-01-22

    Rare diseases are a global public health concern, affecting an estimated 350 million individuals. Only 5% of approximately 7000 known rare diseases have a treatment, and only about half have a patient advocacy organization. Biopharmaceutical companies face complex challenges in developing treatments for rare diseases. Patient advocacy organizations may play a major role by positively influencing research and development, clinical trials, and regulations. Thus, collaboration among patient advocacy organizations and industry is essential to bring new therapeutics to patients. We identified an unmet need for guidelines on day-to-day decision-making by rare disease patient advocacy organizations when working with biopharmaceutical partners. We convened an Independent Expert Panel experienced in collaborations between patient advocacy organizations and biopharmaceutical companies (April 2017) to develop consensus guidelines for these relationships. The guidelines were based on an original version by the International Fibrodysplasia Ossificans Progressiva Association (IFOPA). The Expert Panel reviewed and broadened these to be applicable to all patient advocacy organizations. Comments on the draft Guidelines were provided first by Panel participants and subsequently by six independent experts from patient advocacy organizations and industry. The Panel comprised four experts from the rare disease community who lead patient advocacy organizations; three leaders who perform advocacy functions within biopharmaceutical companies; and two facilitators, both having leadership experience in rare diseases and industry. The finalized Guidelines consist of four main sections: Identification and Engagement With Companies, Patient Engagement and Patient Privacy, Financial Contributions, and Clinical Trial Communication and Support. The Guidelines address the daily considerations, choices, and consequences of patient advocacy organizations as they engage with biopharmaceutical

  7. Origin and distribution of hydrocarbons and organic matter in the surficial sediments of the Sfax-Kerkennah channel (Tunisia, Southern Mediterranean Sea)

    International Nuclear Information System (INIS)

    Zaghden, Hatem; Tedetti, Marc; Sayadi, Sami; Serbaji, Mohamed Moncef; Elleuch, Boubaker; Saliot, Alain

    2017-01-01

    We investigated the origin and distribution of aliphatic and polycyclic aromatic hydrocarbons (AHs and PAHs) and organic matter (OM) in surficial sediments of the Sfax-Kerkennah channel in the Gulf of Gabès (Tunisia, Southern Mediterranean Sea). TOC, AH and PAH concentrations ranged 2.3–11.7%, 8–174 μg g −1 sed. dw and 175–10,769 ng g −1 sed. dw, respectively. The lowest concentrations were recorded in the channel (medium sand sediment) and the highest ones in the Sfax harbor (very fine sand sediment). AHs, PAHs and TOC were not correlated for most of the stations. TOC/N and δ 13 C values revealed a mixed origin of OM with both marine and terrestrial sources. Hydrocarbon molecular composition highlighted the dominance of petrogenic AHs and the presence of both petrogenic and pyrogenic PAHs, associated with petroleum products and combustion processes. This work underscores the complex distribution patterns and the multiple sources of OM and hydrocarbons in this highly anthropogenized coastal environment. - Highlights: • TOC, AHs and PAHs ranged 2–12%, 8–174 μg g −1 sed. dw and 175–10,769 ng g −1 sed. dw. • Lowest concentrations in the Sfax-Kerkennah channel, highest ones in the Sfax harbor • Decoupling between TOC, AH and PAH contents • TOC/N and δ 13 C values revealed a mixed origin of OM with marine and terrestrial sources. • Dominance of petrogenic AHs and presence of both petrogenic and pyrogenic PAHs

  8. Health effects of low level exposure to ionizing radiation: origin and development of a controversy

    International Nuclear Information System (INIS)

    Masse, Roland

    2014-06-01

    Health hazard assessment related to doses of ionizing radiation lower than 100-200 mSv is a matter of controversy, and more acutely when choosing transition towards a new energetic paradigm. Neither epidemiological nor experimental data can be used to determine the shape of the dose-effect relationship from 0 to 100 mSv. Recently, however, long term follow-up of children and young adults exposed to CT scans evidenced that doses of 50 to 60 mGy delivered at high dose-rate were associated to a significant increase of leukemias and cancers, including brain cancer. On the basis of the available data, this article leaves some questions about the plausibility of the linear no threshold hypothesis (LNT) used by radiological protection bodies to control overexposure of the members of public and workers. It concludes that although the plausibility of LNT is fairly weak, using LNT helps to situate the order of magnitude of health risks associated with the development of nuclear power plants and to compare them with those resulting from burning fossil fuels and biomass; the results show that sparing human lives can only be achieved with nuclear for the same quantity of energy produced. (author)

  9. Origin and distribution of hydrocarbons and organic matter in the surficial sediments of the Sfax-Kerkennah channel (Tunisia, Southern Mediterranean Sea).

    Science.gov (United States)

    Zaghden, Hatem; Tedetti, Marc; Sayadi, Sami; Serbaji, Mohamed Moncef; Elleuch, Boubaker; Saliot, Alain

    2017-04-15

    We investigated the origin and distribution of aliphatic and polycyclic aromatic hydrocarbons (AHs and PAHs) and organic matter (OM) in surficial sediments of the Sfax-Kerkennah channel in the Gulf of Gabès (Tunisia, Southern Mediterranean Sea). TOC, AH and PAH concentrations ranged 2.3-11.7%, 8-174μgg -1 sed.dw and 175-10,769ngg -1 sed.dw, respectively. The lowest concentrations were recorded in the channel (medium sand sediment) and the highest ones in the Sfax harbor (very fine sand sediment). AHs, PAHs and TOC were not correlated for most of the stations. TOC/N and δ 13 C values revealed a mixed origin of OM with both marine and terrestrial sources. Hydrocarbon molecular composition highlighted the dominance of petrogenic AHs and the presence of both petrogenic and pyrogenic PAHs, associated with petroleum products and combustion processes. This work underscores the complex distribution patterns and the multiple sources of OM and hydrocarbons in this highly anthropogenized coastal environment. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. 76 FR 50224 - Medicare Program; Accountable Care Organization Accelerated Development Learning Sessions; Center...

    Science.gov (United States)

    2011-08-12

    ...] Medicare Program; Accountable Care Organization Accelerated Development Learning Sessions; Center for... (CMS). This two-day training session is the second Accelerated Development Learning Session (ADLS.... Through Accelerated Development Learning Sessions (ADLS), the Innovation Center will test whether...

  11. 76 FR 66931 - Medicare Program; Accountable Care Organization Accelerated Development Learning Sessions; Center...

    Science.gov (United States)

    2011-10-28

    ...] Medicare Program; Accountable Care Organization Accelerated Development Learning Sessions; Center for... Services (CMS). This two-day training session is the third and final Accelerated Development Learning... the quality of care for beneficiaries. Through Accelerated Development Learning Sessions (ADLS), the...

  12. From Charity to Development: Christian International Health Organizations, 1945-1978

    Directory of Open Access Journals (Sweden)

    Walter Bruchhausen

    2016-12-01

    Full Text Available With the exception of the Red Cross the history of non-governmental international organizations in the field of health has received less attention from historians than intergovernmental organizations and national non-governmental organizations (NGOs. This article takes up the challenge of redressing this by examining the origins and policies of Christian agencies such as Medicus Mundi Internationalis (International Organisation for Medical Cooperation and the World Council of Churches Christian Medical Commission. Despite denominational and theological differences a story emerges of a common trajectory from a hospital-based focus on curative medicine to community-focused primary healthcare in the three decades or so after 1945.

  13. Kidney organ donation: developing family practice initiatives to reverse inertia

    Science.gov (United States)

    2010-01-01

    Background Kidney transplantation is associated with greater long term survival rates and improved quality of life compared with dialysis. Continuous growth in the number of patients with kidney failure has not been matched by an increase in the availability of kidneys for transplantation. This leads to long waiting lists, higher treatment costs and negative health outcomes. Discussion Misunderstandings, public uncertainty and issues of trust in the medical system, that limit willingness to be registered as a potential donor, could be addressed by community dissemination of information and new family practice initiatives that respond to individuals' personal beliefs and concerns regarding organ donation and transplantation. Summary Tackling both personal and public inertia on organ donation is important for any community oriented kidney donation campaign. PMID:20478042

  14. Toward Vision Oriented Organization through Foresight Capability Development

    Directory of Open Access Journals (Sweden)

    Gianita BLEOJU

    2014-11-01

    Full Text Available Dealing with complexity is becoming increasingly difficult for organizations, due to limited replicable abilities, once management performance was remunerated by successful decisions on the marketplace. The competitive advantage, based upon current documented organizational management expertise, deployed into patterns of competitive behavior, prove to be unsustainable. Therefore, we assist to a relative emergency of strategic intelligence adjustment framework, to channel the managerial capability mechanisms, from current detective orientation capabilities toward anticipatory ones. Based upon exploitation of an organizational profiling database, we try our contribution to this challenging debate, by formulating recommendations for strategic adjustment and prototype testing of the potential solutions, through a designed transition matrix from market oriented to vision oriented organizations.

  15. DEVELOP NEW TOTAL ORGANIC CARBON/SPECIFIC UV ...

    Science.gov (United States)

    The purpose of this project is to provide a total organic carbon (TOC)/specific ultraviolet absorbance (SUVA) method that will be used by the Office of Ground Water and Drinking Water (OGWDW) to support monitoring requirements of the Stage 2 Disinfectant/Disinfection By-products (D/DBP) Rule. The Stage 2 Rule requires that enhanced water treatment be used if the source water is high in aquatic organic matter prior to the application of a disinfectant. Disinfectants (chlorine, ozone, etc.) are used in the production of drinking water in order to reduce the risk of microbial disease. These disinfectants react with the organic material that is naturally present in the source water to form disinfection by-products (DBPs). Exposure to some of these by-products may pose a long term health risk. The number and nature of DBPs make it impossible to fully characterize all of the by-products formed during the treatment of drinking water and it is more cost effective to reduce formation of DBPs than to remove them from the water after they are formed. Two measurements (TOC and SUVA) are believed to be predictive of the amount of by-products that can be formed during the disinfection of drinking water and are considered to be surrogates for DBP precursors. SUVA is calculated as the ultraviolet absorption at 254nm (UV254) in cm-1 divided by the mg/L dissolved organic carbon (DOC) concentration (measured after filtration of the water through a 0.45um pore-diameter filte

  16. Nuclear safety with operational approach: towards development organization that learn

    International Nuclear Information System (INIS)

    Campos Remiro, R.; Morales de la Cruz, O.

    2014-01-01

    The comprehensive analysis of the latest relevant events that occurred in plants Spanish nuclear, coupled with requirements and requirements imposed in the Nuclear sector, show the anticipation as a necessary tool for ensure a better and more flexible operation of the plant. Such notice must integrated into the operational focus of the units which constitute the Central; process which, in turn, must become one of the pillars of all organization focused in learning. (Author)

  17. The Search for Organic Compounds of Martian Origin in Gale Crater by the Sample Analysis at Mars (SAM) Instrument on Curiosity

    Science.gov (United States)

    Glavin, Daniel; Freissinet, Caroline; Mahaffy, Paul; Miller, Kristen; Eigenbrode, Jennifer; Summons, Roger; Archer, Douglas, Jr.; Brunner, Anna; Martin, Mildred; Buch, Arrnaud; hide

    2014-01-01

    ). Chloromethane and dichloromethane were also identified after thermal volatilization of the surface soils by the GCMS instruments at the Viking landing sites, although no other chlorinated hydrocarbons were reported (Biemann et al. 1977). Here we focus on the origin of the chlorinated hydrocarbons detected in the Sheepbed mudstone by SAM and the implications for the preservation of organic matter in near-surface materials on Mars.

  18. Attitudes of green organizations' personnel toward genuine sustainable development

    NARCIS (Netherlands)

    Allevato, Camillo

    2017-01-01

    Layman's summary: This thesis dissertation concerns the identification of the main factors that influence attitudes towards genuine sustainable development, in order to identify strategies that will be more effective in education for quality sustainable development. In the pursuit of genuine

  19. Influence of contemporary carbon originating from the 2003 Siberian forest fire on organic carbon in PM2.5 in Nagoya, Japan

    International Nuclear Information System (INIS)

    Ikemori, Fumikazu; Honjyo, Koji; Yamagami, Makiko; Nakamura, Toshio

    2015-01-01

    In May 2003, high concentrations of organic carbon (OC) in PM 2.5 were measured in Nagoya, a representative metropolitan area in Japan. To investigate the influence of possible forest fires on PM 2.5 in Japan via long-range aerosol transport, the radiocarbon ( 14 C) concentrations of PM 2.5 samples from April 2003 to March 2004 were measured. 14 C concentrations in total carbon (TC) from May to early June showed higher values than those in other periods. The OC/elemental carbon (EC) ratios from May to early June were also significantly higher than the ones in other periods. In addition, OC concentrations from May to early June were typically high. These results indicate that the abundant OC fraction from May to early June in Nagoya consisted predominantly of contemporary carbon. Furthermore, simulations of diffusion and transport of organic matter (OM) in East Asia showed that abundant OM originating from East Siberia spread over East Asia and Japan in May and early June. Backward air mass trajectories from this time frame indicate that the air mass in Nagoya likely first passed through East Siberia where fire events were prevalent. However, the backward trajectories showed that the air mass after early June did not originate mainly from Siberia, and correspondingly, the 14 C and OC concentrations showed lower values than those from May to early June. Therefore, the authors conclude that contemporary carbon originating from the forest fire in East Siberia was transported to Nagoya, where it significantly contributed to the high observed concentrations of both OC and 14 C. - Highlights: • We analyzed the radiocarbon ( 14 C) concentration of TC in PM 2.5 from Nagoya, Japan. • 14 C concentrations from May to early June in 2003 were elevated. • The air mass at this time in Nagoya likely first passed through East Siberia. • Fire location data from MODIS indicate that fire events were prevalent in East Siberia. • Contemporary carbon emitted from the Siberian

  20. Influence of contemporary carbon originating from the 2003 Siberian forest fire on organic carbon in PM{sub 2.5} in Nagoya, Japan

    Energy Technology Data Exchange (ETDEWEB)

    Ikemori, Fumikazu, E-mail: ikemori@nagoyakankaken.net [Nagoya City Institute for Environmental Sciences, 5-16-8, Toyoda, Minami-ku, Nagoya 457-0841 (Japan); Graduate School of Environmental Studies, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464–8601 (Japan); Honjyo, Koji [Graduate School of Environmental Studies, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464–8601 (Japan); Yamagami, Makiko [Nagoya City Institute for Environmental Sciences, 5-16-8, Toyoda, Minami-ku, Nagoya 457-0841 (Japan); Nakamura, Toshio [Centre for Chronological Research, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8602 (Japan)

    2015-10-15

    In May 2003, high concentrations of organic carbon (OC) in PM{sub 2.5} were measured in Nagoya, a representative metropolitan area in Japan. To investigate the influence of possible forest fires on PM{sub 2.5} in Japan via long-range aerosol transport, the radiocarbon ({sup 14}C) concentrations of PM{sub 2.5} samples from April 2003 to March 2004 were measured. {sup 14}C concentrations in total carbon (TC) from May to early June showed higher values than those in other periods. The OC/elemental carbon (EC) ratios from May to early June were also significantly higher than the ones in other periods. In addition, OC concentrations from May to early June were typically high. These results indicate that the abundant OC fraction from May to early June in Nagoya consisted predominantly of contemporary carbon. Furthermore, simulations of diffusion and transport of organic matter (OM) in East Asia showed that abundant OM originating from East Siberia spread over East Asia and Japan in May and early June. Backward air mass trajectories from this time frame indicate that the air mass in Nagoya likely first passed through East Siberia where fire events were prevalent. However, the backward trajectories showed that the air mass after early June did not originate mainly from Siberia, and correspondingly, the {sup 14}C and OC concentrations showed lower values than those from May to early June. Therefore, the authors conclude that contemporary carbon originating from the forest fire in East Siberia was transported to Nagoya, where it significantly contributed to the high observed concentrations of both OC and {sup 14}C. - Highlights: • We analyzed the radiocarbon ({sup 14}C) concentration of TC in PM{sub 2.5} from Nagoya, Japan. • {sup 14}C concentrations from May to early June in 2003 were elevated. • The air mass at this time in Nagoya likely first passed through East Siberia. • Fire location data from MODIS indicate that fire events were prevalent in East Siberia.

  1. Mapping replication origins in yeast chromosomes.

    Science.gov (United States)

    Brewer, B J; Fangman, W L

    1991-07-01

    The replicon hypothesis, first proposed in 1963 by Jacob and Brenner, states that DNA replication is controlled at sites called origins. Replication origins have been well studied in prokaryotes. However, the study of eukaryotic chromosomal origins has lagged behind, because until recently there has been no method for reliably determining the identity and location of origins from eukaryotic chromosomes. Here, we review a technique we developed with the yeast Saccharomyces cerevisiae that allows both the mapping of replication origins and an assessment of their activity. Two-dimensional agarose gel electrophoresis and Southern hybridization with total genomic DNA are used to determine whether a particular restriction fragment acquires the branched structure diagnostic of replication initiation. The technique has been used to localize origins in yeast chromosomes and assess their initiation efficiency. In some cases, origin activation is dependent upon the surrounding context. The technique is also being applied to a variety of eukaryotic organisms.

  2. Usability challenges in an Ethiopian software development organization

    DEFF Research Database (Denmark)

    Teka, Degif; Dittrich, Yvonne; Kifle, Mesfin

    2016-01-01

    Usability and user centered design (UCD) are central to software development. In developing countries, the gap between IT development and the local use situation is larger than in western countries. However, usability is neither well addressed in software practice nor at the policy making level...... in Ethiopia. Software practitioners focus on functional requirements, meeting deadlines and budget. The software development industry in Ethiopia is in its early stage. The article aims at understanding usability practices in an Ethiopian software development company. Developers, system analysts, product...... configuration, their experience, cultural knowledge and common sense regarding the users' situation guided the design. Prototypes and fast delivery of working versions helped in getting user feedback even if early user focus proved to be a challenge as communication between developers and users suffered from...

  3. Bidirectional global spontaneous network activity precedes the canonical unidirectional circuit organization in the developing hippocampus.

    Science.gov (United States)

    Shi, Yulin; Ikrar, Taruna; Olivas, Nicholas D; Xu, Xiangmin

    2014-06-15

    Spontaneous network activity is believed to sculpt developing neural circuits. Spontaneous giant depolarizing potentials (GDPs) were first identified with single-cell recordings from rat CA3 pyramidal neurons, but here we identify and characterize a large-scale spontaneous network activity we term global network activation (GNA) in the developing mouse hippocampal slices, which is measured macroscopically by fast voltage-sensitive dye imaging. The initiation and propagation of GNA in the mouse is largely GABA-independent and dominated by glutamatergic transmission via AMPA receptors. Despite the fact that signal propagation in the adult hippocampus is strongly unidirectional through the canonical trisynaptic circuit (dentate gyrus [DG] to CA3 to CA1), spontaneous GNA in the developing hippocampus originates in distal CA3 and propagates both forward to CA1 and backward to DG. Photostimulation-evoked GNA also shows prominent backward propagation in the developing hippocampus from CA3 to DG. Mouse GNA is strongly correlated to electrophysiological recordings of highly localized single-cell and local field potential events. Photostimulation mapping of neural circuitry demonstrates that the enhancement of local circuit connections to excitatory pyramidal neurons occurs over the same time course as GNA and reveals the underlying pathways accounting for GNA backward propagation from CA3 to DG. The disappearance of GNA coincides with a transition to the adult-like unidirectional circuit organization at about 2 weeks of age. Taken together, our findings strongly suggest a critical link between GNA activity and maturation of functional circuit connections in the developing hippocampus. Copyright © 2013 Wiley Periodicals, Inc.

  4. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    In this rega educational theory has proposed a teaching approa which is called ..... that they serve as major factors in guiding and influencing teachers' thoughts ... cognitive development and language are shaped by a student's interaction with ...

  5. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    of plants lies in chemical components cal ... ical screening, content of total phenolics, antifungal and ... provide lead compounds for developing new drugs ..... from extracts and to determine their biological activities. ... Authors also thank Prof.

  6. Original Researc Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    communication skills were identified as peer mediat respectively. ... allows students to work together in small peer whereby .... and achievement in academic performance are worth ..... cognitive development influence each other, in such a.

  7. 24 CFR 92.208 - Eligible community housing development organization (CHDO) operating expense and capacity...

    Science.gov (United States)

    2010-04-01

    ... development organization. Such costs include salaries, wages, and other employee compensation and benefits; employee education, training, and travel; rent; utilities; communication costs; taxes; insurance; equipment...

  8. Eco-organic tourism as an element of the sustainable development of territories

    Science.gov (United States)

    Ivanov, D. V.; Ziganshin, I. I.

    2018-01-01

    Organic agricultural production is an ecologically oriented alternative to traditional agriculture and is aimed at ensuring food and environmental safety of the population and territories. The development of ecological tourism on the basis of organic production farms is considered as a promising direction in the development of regional programs for the sustainable development of territories. Studies have shown that, farms engaged in the production of organic products in the Republic of Tatarstan have a significant potential for the development of eco-organic tourism using elements of the nature protection structure.

  9. 78 FR 42084 - Cooperative Agreement to Support the World Trade Organization's Standards and Trade Development...

    Science.gov (United States)

    2013-07-15

    ...] Cooperative Agreement to Support the World Trade Organization's Standards and Trade Development Facility... The STDF is a unique global partnership established by the Food and Agriculture Organization, World... cooperative agreement in fiscal year 2013 (FY 2013) to the World Trade Organization's (WTO) Standards and...

  10. An original SERPINA3 gene cluster: Elucidation of genomic organization and gene expression in the Bos taurus 21q24 region

    Directory of Open Access Journals (Sweden)

    Ouali Ahmed

    2008-04-01

    Full Text Available Abstract Background The superfamily of serine proteinase inhibitors (serpins is involved in numerous fundamental biological processes as inflammation, blood coagulation and apoptosis. Our interest is focused on the SERPINA3 sub-family. The major human plasma protease inhibitor, α1-antichymotrypsin, encoded by the SERPINA3 gene, is homologous to genes organized in clusters in several mammalian species. However, although there is a similar genic organization with a high degree of sequence conservation, the reactive-centre-loop domains, which are responsible for the protease specificity, show significant divergences. Results We provide additional information by analyzing the situation of SERPINA3 in the bovine genome. A cluster of eight genes and one pseudogene sharing a high degree of identity and the same structural organization was characterized. Bovine SERPINA3 genes were localized by radiation hybrid mapping on 21q24 and only spanned over 235 Kilobases. For all these genes, we propose a new nomenclature from SERPINA3-1 to SERPINA3-8. They share approximately 70% of identity with the human SERPINA3 homologue. In the cluster, we described an original sub-group of six members with an unexpected high degree of conservation for the reactive-centre-loop domain, suggesting a similar peptidase inhibitory pattern. Preliminary expression analyses of these bovSERPINA3s showed different tissue-specific patterns and diverse states of glycosylation and phosphorylation. Finally, in the context of phylogenetic analyses, we improved our knowledge on mammalian SERPINAs evolution. Conclusion Our experimental results update data of the bovine genome sequencing, substantially increase the bovSERPINA3 sub-family and enrich the phylogenetic tree of serpins. We provide new opportunities for future investigations to approach the biological functions of this unusual subset of serine proteinase inhibitors.

  11. Collaborative Development: A New Culture Affects an Old Organization

    Science.gov (United States)

    Phelps, Jim; Ruzicka, Terry

    2008-01-01

    At the University of Wisconsin (UW)-Madison, the Registrar's Office and the Division of Information Technology (DoIT) apply a collaborative development process to joint projects. This model differs from a "waterfall" model in that technical and functional staff work closely to develop requirements, prototypes, and the product throughout…

  12. Using Organization Development To Improve School Climate. Report No. 17.

    Science.gov (United States)

    Gottfredson, Gary D.; Gottfredson, Denise C.

    This paper presents and illustrates some principles for organizational development approaches to improving school climate. It discusses a specific structure for facilitating school improvement entitled Program Development Evaluation, and it illustrates the use of school climate assessments for school diagnosis and the evaluation of improvement…

  13. Aggressive Neglect, Matrix Organization, and Student Development Implementation

    Science.gov (United States)

    Borland, David T.

    1977-01-01

    Organizational facilitation of student development is a significant but difficult process in colleges and universities with traditional priorities on academic concerns. Organizational factors are analyzed and a model is proposed implementing student development through the accommodation of diverse organizational elements and by an integrated…

  14. Development of an Origin Trace Method based on Bayesian Inference and Artificial Neural Network for Missing or Stolen Nuclear Materials

    Energy Technology Data Exchange (ETDEWEB)

    Bin, Yim Ho; Min, Lee Seung; Min, Kim Kyung; Jeong, Hong Yoon; Kim, Jae Kwang [Nuclear Security Div., Daejeon (Korea, Republic of)

    2014-05-15

    Thus, 'to put nuclear materials under control' is an important issue for prosperity mankind. Unfortunately, numbers of illicit trafficking of nuclear materials have been increased for decades. Consequently, security of nuclear materials is recently spotlighted. After the 2{sup nd} Nuclear Security Summit in Seoul in 2012, the president of Korea had showed his devotion to nuclear security. One of the main responses for nuclear security related interest of Korea was to develop a national nuclear forensic support system. International Atomic Energy Agency (IAEA) published the document of Nuclear Security Series No.2 'Nuclear Forensics Support' in 2006 to encourage international cooperation of all IAEA member states for tracking nuclear attributions. There are two main questions related to nuclear forensics to answer in the document. The first question is 'what type of material is it?', and the second one is 'where did the material come from?' Korea Nuclear Forensic Library (K-NFL) and mathematical methods to trace origins of missing or stolen nuclear materials (MSNMs) are being developed by Korea Institute of Nuclear Non-proliferation and Control (KINAC) to answer those questions. Although the K-NFL has been designed to perform many functions, K-NFL is being developed to effectively trace the origin of MSNMs and tested to validate suitability of trace methods. New fuels and spent fuels need each trace method because of the different nature of data acquisition. An inductive logic was found to be appropriate for new fuels, which had values as well as a bistable property. On the other hand, machine learning was suitable for spent fuels, which were unable to measure, and thus needed simulation.

  15. Fine-needle aspiration cytology: its origin, development, and present status with special reference to a developing country, India.

    Science.gov (United States)

    Das, Dilip K

    2003-06-01

    one or more ancillary techniques on fine-needle aspirates were adopted in 72.5% centers. Of the 772 publications from the developing world during 1987-2002, India alone contributed to 374 (48.4%). During 1975-2002, 154 articles on FNA were published needles were used in all the centers, but syringe holders were used in only in 61% of centers. In 86% of laboratories, two or more routine stains were used, and one or more ancillary techniques on fine-needle aspirates were adopted in 72.5% centers. Of the 772 publications from the developing world during 1987-2002, India alone contributed to 374 (48.4%). During 1975-2002, 154 articles on FNA were published in 15 indexed Indian journals.

  16. Original Researc Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    Abstract. The aim of the present research is to develop the f effect of ... Science, Technology and Arts Research J. Sci. Technol. ..... “Science, Technology and Innovation for National ... Latin American Journal of Pharmacy 3: 1135-1141. Vemula ...

  17. Original Researc Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    2009-09-17

    Sep 17, 2009 ... agriculture systems in Edo state, Nigeria and char ... were inferred as different varieties of the species of th ... tate, Nigeria and characterize them using molecular marker ... Article Information ... The development of Polymerase Chain Reaction (PCR) ... Quarters, University of Benin Teaching Hospital.

  18. Original Researc Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    financial, emotional, personal and social costs fo families and twins themselves. It accounts for a. 10% of perinatal mortality (Dera et al., 2007; Gess. 2007 and Abasiattai et al., 2010). A number of unique complications develop i pregnancies. They include conjoined twinning, t twin transfusion syndrome (TTTS), growth discor.

  19. Original Research Original Research

    African Journals Online (AJOL)

    User

    The work aims at developing a strategy for the ide target by analyzing signaling pathways. The strateg and tested in concern with Toll Like Receptor. TLR4 pathway is a major pathway which ge polysaccheride (LPS) stimulus. The work describe potent drug targets by understanding the flow of pathways by representing them ...

  20. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    Abstract. This study focused on the evaluation of supply variability. Nigeria. The field work of the study involved the use installation of water meters to obtain data on household within the metropolis. The findings of the study revealed water use was 86.22 liters/capita/day which liters/capita/day for developing nations.