This article explores the work of Czech theatre director Jakub Krofta in the context of ecocriticism. This discussion focuses on Krofta's two productions directed for Polish puppetry theatres and aimed at young audiences: Daszeńka (Teatr Lalka, Warsaw, 2011), based on Karel Čapek's book, and Pacan – historia o miłości (Pacan – a story about love; Wrocławski Teatr Lalek, Wrocław, 2012). My analysis is framed by Greta Gaard's theories on ecopedagogy (GAARD 2009) and Paul Piris's discussion on c...
In the Warsaw Ghetto established by the German Nazis as a special district for Polish Jews in 1940 there were two typhus epidemics. Many patients affected by this disease (1500 during the first and 6500 during second epidemic) were treated at The Department of Infectious Disease of Czyste Hospital headed by Dr Jakub Penson--a Polish physician of Jewish origin. A heroic group of 20 physicians not only treated patients in these tragic circumstances, but also performed in defiance of Nazi prohibition, scientific studies on the clinical course of typhus with special attention on hyperazotemia and renal complication. The results of their observations were presented in 1941-42 during clinical meetings in Czyste Hospital and later published by Penson in 1946 in the Polish Physicians Weekly. Among other clinical statements a description of acute renal failure of extrarenal origin, caused by dehydration and toxic influence of primary disease seems the most important one. It has to be taken into account that acute renal failure appearing during Crush Syndrome was described by Bywaters in 1941. Jakub Penson survived the German Nazi occupation and later become a head of the Internal Medicine Department in Gdansk Medical University and one of the precursors of clinical nephrology in Poland.
Jakub Luukase rolli eest mängufilmis "Georgica" sai E. Aavik parima meesosatäitja preemia Minski filmifestivalil "Listapad 99". Barcelona VI rahvusvahelisel filmifestivalil L'Alternativa '99 sai film parima mängufilmi preemia
marketing in it's - Jakub Mařík from BSNAP agency. Using a questionnaire, the thesis also examines how influencers' audience views their brand collaborations. In the last part of the thesis, a case study
Roč. 62, č. 4 (2014), s. 619-637 ISSN 0009-0468 R&D Projects: GA ČR(CZ) GA14-32413S Institutional support: RVO:68378068 Keywords : Deml, Jakub * correspondence * editions Subject RIV: AJ - Letters, Mass-media, Audiovision
Jedličková, Alice; Fedrová, Stanislava
Roč. 57, č. 1 (2010), s. 29-59 ISSN 0037-6973 Institutional research plan: CEZ:AV0Z90560517 Keywords : narrative * ekphrasis * visuality * descriptivity * intermedia studies * Urban, Miloš * Arbes, Jakub Subject RIV: AJ - Letters, Mass-media, Audiovision
Jakub Luukase rolli eest mängufilmis "Georgica" sai E. Aavik parima meesosatäitja preemia Minski filmifestivalil "Listapad 99". Barcelona VI rahvusvahelisel filmifestivalil L'Alternativa '99 sai film parima mängufilmi preemia. Film jookseb Pariisi kinos Studio des Ursulines ja tuleb ekraanile ka Hollandis
Jakub Sobieski’s Description of the Moscow Campaign (based on the Diariusz ekspedycyjej moskiewskiej dwuletniej królewica Władysława Anno Domini 1617 [The Diary of the Two-Year Moscow Campaign by Royal Prince Władysław in 1617
Full Text Available The essay discusses Jakub Sobieski’s diaries and memories, which belong to the finest specimens of such writing in Polish Baroque. The diary and memoirs of the Moscow campaign of 1617-1618 have survived in only a few copies, with the most important ones in Biblioteka Czartoryskich in Cracow. Reconstruction of Prince Władysław’s struggle for the Russian crown is mostly based on a handwritten testimony called Diariusz ekspedycyjej moskiewskiej dwuletniej królewica Władysława A. D. 1617 [The Diary of the Two-Year Moscow Campaign by Royal Prince Władysław in 1617]. The events described in the diary span from April 5th, 1617 to December 28th, 1618. The author has arranged the material chronologically, focusing on the text as historical evidence. The conclusion of the text, where Sobieski quotes a fragment of Tacitus’s Annals, points out to the argumentative function of the work, which was supposed to explain to Poles (the king, the sejm and senate, the nobility that commissaries were right in signing the Truce of Deulino, regarding the safety of the homeland threatened by Turks and Tatars, and the budgetary difficulties of the Crown and Lithuania. The second work by Sobieski is more of a Baroque memoir, composed as a temporal sequence (some fragments have the structure of diary. The author reconstructs the events of the Moscow campaign, beginning with the death of tsar Ivan the Terrible (1584, and leads the narrative to the end of 1618, when the Truce of Deulino. The work is characterized by greater coherence in presentation of facts, their selection, and a more general point of view, pointing out to the failure of Polish dynastic policy. Sobieski seems to be critical of the Polish intervention and the Polish raison d’état in this respect. He is also critical of the young prince’s campaign of 1617-1618; he was a commissioner for treaties with Moscow during the campaign.
Roč. 62, č. 1/2 (2017), s. 19-25 ISSN 2570-6861 R&D Projects: GA ČR(CZ) GA16-09064S Institutional support: RVO:67985955 Keywords : Jakub Srnec of Varvažov * proverbs * Adagia * commonplace books * Neo-Latin literature Subject RIV: AJ - Letters, Mass-media, Audiovision OBOR OECD: Specific literatures
Bahovski, Erkki, 1970-
Ilmunud ka: Postimees : na russkom jazõke 21. dets., lk. 8 (lühendatud). Austria suursaadik Eestis dr Jakub Forst-Battaglia sõnul pingutab 2006. aasta jaanuaris Suurbritannialt järgmiseks pooleks aastaks Euroopa Liidu juhtimise üle võttev Austria pingutab EL-i laienemise nimel, läbirääkimised on alustatud Türgi ja Horvaatiaga
Smolka, J.; Purš, Ivo
-, č. 14 (2014), s. 101-113 ISSN 1213-5372 R&D Projects: GA ČR GAP405/12/1268 Institutional support: RVO:68378033 Keywords : alchemy * heraldry * symbols * Rudolf II * Voynich manuscript Subject RIV: AL - Art, Architecture, Cultural Heritage
Vahala, Linda [Old Dominion Univ., Norfolk, VA (United States)
During the period 1998-2013, research under the auspices of the Department of Energy was performed on RF waves in plasmas. This research was performed in close collaboration with Josef Preinhaelter, Jakub Urban, Vladimir Fuchs, Pavol Pavlo and Frantisek Zacek (Czech Academy of Sciences), Martin Valovic and Vladimir Shevchenko (Culham). This research is detailed and all 38 papers which were published by this team are cited.
Title: Automated Generation of Realistic Terrain Using Machine Learning Tech- niques Author: Jakub Střelský Department: Department of Theoretical Computer Science and Mathematical Logic Supervisor: RNDr. Pavel Surynek, Ph.D., Department of Theoretical Computer Science and Mathematical Logic Abstract: Artificial terrain is important component of computer games, simulati- ons and films. Manual terrain creation can be arduous process, hence automa- tization of this process would be convenient in...
The first developmental stages of advertising in traditional media Jakub Kesl Abstract Diploma thesis "The first developmental stages of advertising in traditional media" deals with the commercial use of media in its first forms and handles the evolution of advertising communication in conjunction with the development of media. Traditional media - print, radio and television in the period starting with emergence of these media until the point of establishment of advertising as their more or l...
such as NXP, Atmel, Samsung, and STMicrosystems have similar product lineups . 7 The CPU operates at clock rates from 3.57 MHz up to 66 MHz, depending on...verification procedure confounds both of these expectations. First, the SIM lock-out counter only allows the acquisition of two traces (in the case of the PIN...Ferenc, Jakub. “Power analysis of the PIN verification procedure on smart cards (English title, translated)”, 2006 [cit. 2013-05-13]. URL http
The origins of the contemporary collectorship dates from times when the sameness of art and science was commonly accepted. In those days relics of the ancient past and natural individuals of newly discovered lands were presented at the same time. Cosmological character of the collections manifested the tenacity of recognition and representation of the surrounding reality. A great impact on completion of collections of curiosities in Europe had Netherlands, and in the basin of Baltic Sea a remarkable significance was gained by Hanseatic Gdańsk. Collections of Jakub Breyn, Jakub Klein and Gotfryd Reyger became famous then. In the same way were imported individuals for Anna Jabłonowska that composed one of the most interesting European collections. In course of time merging such a great multiplicity of collections was beyond collectors' power and museum pieces from collections of curiosities were parcelled out. It was a real beginning of specialistic museums. A role of museum for science results from its function of methodical organizing collections that can be used by research workers. However, although the aims of scientific and museum centres are different, they come together on the occasion of museum recognition works when museums' workers borrow essential knowledge and methods from resources of science, and scientists search for useful research materials in museum resources.
Pastusiak, Radosław; Jasiniak, Magdalena; Keller, Jakub; Krzeczewski, Bartłomiej
Niniejszy raport prezentuje wyniki projektu realizowanego w ramach projektu badawczego nr UMO-2013/09/B/HS4/, pt. Efektywność Specjalnych Stref Ekonomicznych, przez zespół Katedry Finansów Korporacji, Wydział Ekonomiczno-Socjologiczny Uniwersytetu Łódzkiego, pod kierownictwem dr hab. Radosława Pastusiaka, prof. nadzw. UŁ. w składzie: dr Magdalena Jasiniak, mgr Jakub Keller, mgr Bartłomiej Krzeczewski. Zasadniczym celem badania było określenie efektywności funkcjonowania Specjalnych Stref Ekon...
Author of the work: Zuzana Benešová Head of the work: Ing. Jakub Stránský, CEMS MIM Goals: Analysis of the system of compensations and benefits among the retail company Ahold Czech Republic, a.s. The connection between the bonuses and store's financial results. Financial interest in other criterias such as: fresh goods, short waitlines, clean store, helpful and friendly staff,... Literature: Cimer P. & Zadražilová D. a kol, Retail Management, Management Press, Praha 2007 Drury C., Management ...
Granovský Palace in Ungelt Abstract This Bachelor's thesis deals with the Renaissance palace, which Jakub Granovský Jr. from Granov let to build in the area of Týn merchant's courtyard in the Old Town of Prague after 1558. The palace complex consisted of today's houses number 639, number 640 and partially intervened in the house number 1049. Existing literature refers to Granovský Palace as a milestone and the beginning of a new period within Renaissance architecture in the Old Town of Prague...
ŽALMAN, Jakub. Impact of EU on the internationalization of Czech SMEs in ICT in-dustry. Diploma thesis. Mendel University in Brno, 2015. The topic of this diploma thesis is how is the fact that Czech Republic is member of the EU influencing internationalization of Czech SMEs operating in ICT industry. EU has opened and unified the internal market a lot which gave new possibilities of internationalization for member countries. Importance of the topic is also given by the facts that small and m...
Bibliografický záznam MIČEK, Jakub. Doping ve fitness a rekreační sport: obsahová analýza českých videí na YouTube. Praha, 2016. 48 s. Bakalářská práce (Bc.) Univerzita Karlova. Fakulta sociálních věd, Institut sociologických důvodů. Katedra sociologie. Vedoucí bakalářské práce PhDr. Mgr. Jan Balon, Ph.D. Abstract Fitness and YouTube are very popular areas of entertainment these days. Despite the touchiness of this topic, there are many videos about doping being published on YouTube. Majority...
Full Text Available The main purpose of the article is to present and describe the reception of Sholem Aleichem’s portrait in the Polish-language Jewish press published in 1918-1939. The basis is created by such serial publications as “Nowy Dziennik” (Krakow, “Chwila”, “Nasza Opinia” (Lviv, “Głos Żydowski”, “Nasz Przegląd” (Warsaw. The aspects connected with the role of Sholem Aleichem as a theatre creator were discussed separately. It was important to point out the first attempts to research a theoretical discourse in the Jewish press about the Jewish humour to give the definition and characteristics (Jakub Appenszlak, Gerszon Lewin and Elchanan Cejtlin.
Full Text Available This article presents the influence that Witold Gombrowicz’s work has had on Polish cinema. It covers several generations of directors, for example, Andrzej Munk (born in the 1920s, Roman Polański and Jerzy Skolimowski (born in the 1930 as well as Agnieszka Holland, Piotr Szulkin and Marek Koterski (born in the 1940s and 1950s, and discusses the topic of film adaptations of his books (Jerzy Skolimowski’s Ferdydurke and Jan Jakub Kolski’s Pornografia [Pornography]. The article shows that Polish cinema uses Gombrowicz’s works most of all by taking up the issue of life’s authenticity and inauthenticity as well as to demythologize Polish tradition and history. As for esthetics, it employs Gombrowicz’s favorite style, i.e. the grotesque.
The article commemorates the activity of Józef Heller starting in 1921 with Jakub Parnas's group in Lvov which investigated the phosphorolysis of glycogen. The unknown events of His biography were disclosed, like military service in the Piłsudski's Legions at the rebirth of the Polish State and, subsequently, during the Nazi occupation of Poland--participation in the clandestine teaching of medical students. In the post-war times Józef Heller undertook teaching of medical students in Wrocław and next in Warsaw. In 1954 He begun to organize the Institute of Biochemistry and Biophysics of the Polish Academy of Sciences--it now continues its activity. Professor Heller initiated the publication in Poland of three major biochemical journals, including Postepy Biochemii (1954). Thanks to His leadership the first Polish Medical Dictionary was published (1981). The article summarizes the pursuit of Józef Heller in various branches of academic life, which were and still are appreciated by subsequent generations of Polish biochemists.
Redazione Reti Medievali (a cura di
Full Text Available Report of PhD dissertations. Andrea Brugnoli Una storia locale: l’organizzazione del territorio veronese nel medioevo: trasformazioni della realtà e schemi notarili (IX-metà XII secolo, Tesi di dottorato di ricerca in Scienze Storiche e Antropologiche (XXII ciclo, Università degli Studi di Verona, 2010 Luca Filangieri Famiglie e gruppi dirigenti a Genova (secoli XII-metà XIII, Tesi di dottorato di ricerca in Storia medievale (XXII ciclo, Università degli Studi di Firenze, 2010 Jakub Kujawi ski Wernakularna kolekcja historiograficzna z rękopisu francuskiego nr 688 z Biblioteki Narodowej w Paryżu. Studium źródłoznawcze (La raccolta dei volgarizzamenti delle opere storiografiche nel manoscritto francese 688 della Biblioteca Nazionale di Parigi, Tesi di dottorato, Università “Adam Mickiewicz”, Facoltà di Storia, Pozna, a.a. 2009/2010 Marta Longhi I signori “de Radicata”. Strategie di affermazione familiare e patrimoniale nel Piemonte dei secoli XII-XIV, Tesi di dottorato di ricerca in Istituzioni, Società, Religioni dal Tardo Antico alla fine del Medioevo (XX ciclo, Università di Torino, 2008
Full Text Available The article presents an analysis of selected functions carried out by the popular cultural references in Żulczyk’s novel Zrób mi jakąś krzywdę, czyli wszystkie gry wideo są o miłości. The first section of the article considers some methodological problems related to the subject matter of the article and discusses the book in view of Shusterman’s aesthetic experience model in the aesthetic legitimization of popular art. The next section includes the analysis of the text and focuses on such issues as references to popular culture in the protagonist’s characteristics. In the conclusion of the article, the author sums up that the popular culture threads are not included in the novel purely for decorative reasons but constitute it at a multi-tiered level and cannot be removed from the novel otherwise it would disrupt, or even destroy, its structure and thus, without some knowledge of the basic elements of pop culture, the reading and understanding of the book can be substantially impaired and incomplete.
Full Text Available The article concentrates on an interesting 130-year-old artefact located in the Krakow church of Piarists – the decoration of the place where Stanisław Konarski’s (1700–1773 heart was buried. Konarski was a monk of the Pious Schools in the 18th century, as well as publisher of a collection of national laws Volumina legum, a bold commentator calling for strengthening royal power and abolishing liberum veto, reformer of the educational system and founder of the renowned, modern Collegium Nobilium. The circumstances of the discovery and relocation of the relic in 1882 from Warsaw to Krakow and the ceremony of its introduction to the monastic Church of the Transfiguration of Jesus on February 13 are also outlined. Three significant research issues are also discussed. The first one is the problem of the authenticity of the artefact, which was discovered more than a hundred years after Konarski’s death in the possession of a Warsaw optician Jakub Pik. It was then that the question started occupying the minds of researchers, including the rector of the Krakow college Adam Słotwiński. The question is made more relevant by the lack of any direct evidence from 1773 about the removal of Stanisław Konarski’s heart from his body after his death. The information gathered so far allow us to assume, with probability bordering on certainty, that it is authentic and the only surviving part of this famous monk’s body. Another question, totally absent from past reflections on the subject, is the reason why the heart was removed. This particular aspect turns our attention at a strikingly popular early-modern Polish tradition – first in royal families, later also among magnates and nobility – of burying hearts separately, usually by entombing them in a church founded by the deceased. It was found that a considerable number of hearts removed from bodies had been inhumed in Piarist churches (Rzeszów, Warsaw or Łowicz. This tradition, however, did
Full Text Available Michał Nowak, Katarzyna Królak-Nowak, Aleksandra Sobolewska-Włodarczyk, Jakub Fichna, Marcin Włodarczyk Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, Lodz, Poland Abstract: Venous thromboembolism (VTE is a multifactorial disease manifesting as either deep vein thrombosis or pulmonary embolism. Its prevalence makes VTE a significant issue for both the individual – as a negative factor influencing the quality of life and prognosis – and the society due to economic burden. VTE is the third most common vascular disorder in Western countries, after myocardial infarction and stroke, making it a major cause of in-hospital mortality, responsible for 5%–10% of hospital deaths. Despite many studies conducted, only 50%–60% provoking factors have been identified, while the remaining 40%–50% have been classified as idiopathic or unprovoked. Chronic inflammatory disorders, with their underlying prothrombotic state, reveal an increased risk of VTE (six to eight times compared with the general population. Among the inflammatory disorders, we can identify inflammatory myopathies – a group of rare, chronic diseases featuring weakness and inflammation of muscles with periods of exacerbation and remission; their main classes are polymyositis and dermatomyositis. The objective of this review is to emphasize the need of VTE prophylaxis in individuals with inflammatory myopathies in order to reduce morbidity and mortality rates among those patients and improve their quality of life and prognosis. Keywords: deep vein thrombosis, pulmonary embolism, inflammation, polymyositis, dermatomyositis, prothrombotic state
Kohout, T.; Kletetschka, G.; Wasilewski, P.
The origin of our solar system may have been accompanied by transient energetic events capable of magnetizing the materials from which the solid bodies in the solar system formed. The magnetic field associated with some of some of these events should have been recorded by the magnetic mineralogy contained within meteorites. To extract this information from meteorites many noise components must be carefully eliminated. The fusion crust has long been established as restricted to a thin layer on the surface of meteorite. Magnetic screening of the fusion crust that relates to Murchison meteorite indicates that during the entry and landing at least 6 mm thick layer is affected by terrestrial TRM acquisition. Many of the meteorite finds have long term residence in the terrestrial oxidized environment. This weathering is the subject of this study. The meteorite in question landed in the Libya stony desert and has obvious surface weathering that can be referred to as desert varnish. The consequent iron oxide mineralization introduced very stable origin of very stable chemical remanent magnetization. The magnetic remanence in fragments without the desert varnish is between 20 - 50 % of the oxidized ones. The orientation of this CRM appears to be random indicating that the sample may have rotated during the long period of aeolian transport and varnish formation. Magnetization of the white matrix samples (20 - 50 % of weathered ones) is thermally more stable and also randomly oriented. The range of NRM/SIRM values for both mineralogies varies between 10-2 and 10-3. Acknowledgements: This work would not be possible without help of following people: Jakub Haloda, Petr Jakes, Marcela Bukovanska, Petr Pruner, Vladimir Kohout, Libuse Kohoutova, Vladimir Kohout, Olga Kohoutova.
Full Text Available The present issue of Studies in Second Language Learning and Teaching marks exactly three years of existence of the journal. On the one hand, this has not been a very easy time, mainly because of the fact that, as is the case with any startup publication, it has been extremely difficult to obtain papers that would satisfy the stringent criteria of high-quality academic research, with the effect that the rejection rate has been extremely high, and finding the right reviewers has also often constituted a major challenge. On the other hand, the three years have also witnessed the rise of SSLLT in the field, as we have been privileged to publish papers by prominent scholars in the area of second language acquisition, well-known researchers have consented to act in the capacity of editors of special issues of the journal, and eminent figures have also agreed to review many of the submissions we have received. Equally importantly, there has been increasing interest in the papers we publish, which is evidenced in the growing numbers of downloads and citations, a clear advantage of having both a printed and an online version, the latter of which is accessible to everyone free of charge. I would like to take this opportunity to thank all those who have been involved in the production of the journal over these three years and have spent countless hours to make sure that the final product is each time up to standard. In particular, my sincere thanks go to assistants to the editor Anna Mystkowska-Wiertelak, Jakub Bielak, Mariusz Kruk and Krzysztof Kwiatkowski, our typesetter Piotr Bajak, as well as the authors and anonymous reviewers. Had it not been for their attention to detail, dedication, hard work and support, SSLLT would surely not have gained the position in the field it enjoys today.
Klara Stephanie Szlezák
Full Text Available This essay addresses survivor stories as formulations of Holocaust memory in the U.S. More specifically, it focuses on the former concentration camp at Flossenbürg in southern Germany. Compared to places like Dachau and Buchenwald in Germany or Auschwitz and Treblinka in Poland, Flossenbürg is often absent from or—if present at all—marginalized in the public and scholarly discourse of Holocaust memory. The heavily autobiographical novel Jakub’s World (2005 tells the story of Jakub Szabmacher, a Jewish boy who is taken from his home in Poland by the Nazis and is eventually interned at Flossenbürg. He survives many months of deprivation and hardship in the concentration camp until U.S. forces liberate it in April 1945; orphaned and homeless, he eventually relocates to the U.S., yet returns to the site of his suffering many times. Reading the book against the backdrop of ongoing debates about Holocaust memory in the U.S., this essay explores structural and plot elements in the book that complicate both a Jewish identity derived from victimhood and the notion of liberation as the moment of ultimate redemption. Both Jakub’s World and the Flossenbürg Concentration Camp Memorial as sites of memory actively partake in the commemoration of the Holocaust, offering narratives that not only complicate the notion of World War II as the “Good War” but also reveal the transnational dimension of memories of the Holocaust. Neither the stories and memories of survivors of the Holocaust at Flossenbürg, nor the visitors to the present-day memorial site, nor the characters central to the memoir can be framed, addressed, or understood in the context of national boundaries.
Full Text Available Marta Banach,1,* Jakub Antczak,1,* Rafał Rola21Department of Clinical Neurophysiology, 2First Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland *These authors contributed equally to this workBackground: Myotonic dystrophy (DM type 1 and type 2 are inherited diseases characterized by myotonia and myopathy. Additional symptoms include, among others, peripheral neuropathy and sleep-related breathing disorders (SRBDs. There is growing evidence for a complex association between DM1 and DM2, which was described in patients with diabetes mellitus and in the general population. In this study, we investigated whether there is an association between peripheral neuropathy and SRBDs also in the population of patients with DM.Methods: The study included 16 patients with DM1 (mean age, 37.9±14.1 years; 20–69 years and eight patients with DM2 (mean age, 47.6±14.1 years; 20–65 years, who underwent a sensory and motor nerve conduction study (NCS and diagnostic screening for SRBDs. In both groups, the NCS parameters were correlated with respiratory parameters.Results: In both groups, the amplitude of the ulnar sensory nerve action potential (SNAP correlated with the mean arterial oxygen saturation (SaO2. In addition, in the DM2 group, the median SNAP correlated with the mean SaO2. In the DM1 group, the median SNAP and the distal motor latency (DML of the ulnar nerve correlated with the apnea–hypopnea index, while the oxygen desaturation index correlated with the DML of the tibial nerve and with conduction velocity in the sural nerve.Conclusion: Our results indicate a complex association between neuropathy and SRBDs in DM1 and DM2. Axonal degeneration may contribute to nocturnal hypoxemia and vice versa. Neuropathy may contribute to muscle weakness, which in turn may cause respiratory events.Keywords: myotonic dystrophy, SRBD and neuropathy with AHI, SNAP, CMAP
Full Text Available Pezhman Kazemi,1 Mohammad Hassan Khalid,1 Ana Pérez Gago,2 Peter Kleinebudde,2 Renata Jachowicz,1 Jakub Szlęk,1 Aleksander Mendyk1 1Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland; 2Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine-University, Düsseldorf, Germany Abstract: Dry granulation using roll compaction is a typical unit operation for producing solid dosage forms in the pharmaceutical industry. Dry granulation is commonly used if the powder mixture is sensitive to heat and moisture and has poor flow properties. The output of roll compaction is compacted ribbons that exhibit different properties based on the adjusted process parameters. These ribbons are then milled into granules and finally compressed into tablets. The properties of the ribbons directly affect the granule size distribution (GSD and the quality of final products; thus, it is imperative to study the effect of roll compaction process parameters on GSD. The understanding of how the roll compactor process parameters and material properties interact with each other will allow accurate control of the process, leading to the implementation of quality by design practices. Computational intelligence (CI methods have a great potential for being used within the scope of quality by design approach. The main objective of this study was to show how the computational intelligence techniques can be useful to predict the GSD by using different process conditions of roll compaction and material properties. Different techniques such as multiple linear regression, artificial neural networks, random forest, Cubist and k-nearest neighbors algorithm assisted by sevenfold cross-validation were used to present generalized models for the prediction of GSD based on roll compaction process setting and material properties. The normalized root-mean-squared error and the coefficient of
Full Text Available Mohammad Hassan Khalid,1 Pezhman Kazemi,1 Lucia Perez-Gandarillas,2 Abderrahim Michrafy,2 Jakub Szlęk,1 Renata Jachowicz,1 Aleksander Mendyk1 1Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland; 2Centre National de la Recherche Scientifique, Centre RAPSODEE, Mines Albi, Université de Toulouse, Albi, France Abstract: The effects of different formulations and manufacturing process conditions on the physical properties of a solid dosage form are of importance to the pharmaceutical industry. It is vital to have in-depth understanding of the material properties and governing parameters of its processes in response to different formulations. Understanding the mentioned aspects will allow tighter control of the process, leading to implementation of quality-by-design (QbD practices. Computational intelligence (CI offers an opportunity to create empirical models that can be used to describe the system and predict future outcomes in silico. CI models can help explore the behavior of input parameters, unlocking deeper understanding of the system. This research endeavor presents CI models to predict the porosity of tablets created by roll-compacted binary mixtures, which were milled and compacted under systematically varying conditions. CI models were created using tree-based methods, artificial neural networks (ANNs, and symbolic regression trained on an experimental data set and screened using root-mean-square error (RMSE scores. The experimental data were composed of proportion of microcrystalline cellulose (MCC (in percentage, granule size fraction (in micrometers, and die compaction force (in kilonewtons as inputs and porosity as an output. The resulting models show impressive generalization ability, with ANNs (normalized root-mean-square error [NRMSE] =1% and symbolic regression (NRMSE =4% as the best-performing methods, also exhibiting reliable predictive
Full Text Available Jakub Kortas,1 Katarzyna Prusik,2 Damian Flis,3 Krzysztof Prusik,1 Ewa Ziemann,4 Neil Leaver,5 Jedrzej Antosiewicz6 1Department of Recreation and Tourism, Gdansk University of Physical Education and Sport, Gdansk, Poland; 2Department of Biomedical Basis of Health, Gdansk University of Physical Education and Sport, Gdansk, Poland; 3Department of Bioenergetics and Physiology of Exercise, Medical University of Gdansk, Gdansk, Poland; 4Department of Physiology and Pharmacology, Gdansk University of Physical Education and Sport, Gdansk, Poland; 5The Immunosuppression monitoring service (IMS Laboratory, Royal Brompton & Harefield NHS Foundation Trust, Heart Science Centre, Harefield Hospital, Harefield, UK; 6Department of Biochemistry, Gdansk University of Physical Education and Sport, Gdansk, Poland Background: Despite several, well-documented pro-healthy effects of regular physical training, its influence on body iron stores in elderly people remains unknown. At the same time, body iron accumulation is associated with high risk of different morbidities.Purpose: We hypothesized that Nordic Walking training would result in pro-healthy changes in an elderly group of subjects by reducing body iron stores via shifts in iron metabolism-regulating proteins.Methods: Thirty-seven women aged 67.7±5.3 years participated in this study. They underwent 32 weeks of training, 1-hour sessions three times a week, between October 2012 and May 2013. Fitness level, blood morphology, CRP, vitamin D, ferritin, hepcidin, and soluble Hjv were assessed before and after the training.Results: The training program caused a significant decrease in ferritin, which serves as a good marker of body iron stores. Simultaneously, the physical cardiorespiratory fitness had improved. Furthermore, blood hepcidin was positively correlated with the ferritin concentration after the training. The concentration of blood CRP dropped, but the change was nonsignificant. The applied training
Full Text Available Jakub Taradaj,1 Joanna Rosińczuk,2 Robert Dymarek,2 Tomasz Halski,3 Winfried Schneider4 1Department of Physiotherapy Basics, Academy School of Physical Education in Katowice, Katowice, 2Department of Nervous System Diseases, University of Medicine in Wroclaw, Wroclaw, 3Institute of Physiotherapy, Public Higher Medical Professional School in Opole, Opole, Poland; 4Lymphology Center in Bad Berleburg, Bad Berleburg, Germany Introduction: The primary lymphedema and chronic venous insufficiency present an important medical problem, and effective physical therapeutic methods to treat this problem are still at the search phase. The aim of this study was to compare the efficacy of intermittent pneumatic compression (IPC of a high- or low-pressure level in the treatment of primary phlebolymphedema of the lower limbs.Methods: The study included 81 patients with chronic venous insufficiency and primary lymphedema of the lower limbs. Group A consisted of 28 patients who underwent a monthly antiedematous therapy including a manual lymphatic drainage, multilayer bandaging, and IPC with the output pressure of 120 mmHg. Group B consisted of 27 patients who underwent the same basic treatment as group A and IPC with the output pressure of 60 mmHg. Group C (control consisted of 26 patients who underwent only a basic treatment – without IPC.Results: After completion of the study, it was found that the greatest reduction of edema occurred in patients who underwent treatment with a pressure of 120 mmHg. The comparison of percentage reduction of edema showed a statistically significant advantage of the group A over groups B and C, both for the changes in the right (P=0.01 and the left limb (P=0.01. Results in patients undergoing intermittent compression of the lower pressure (60 mmHg were similar to those obtained in the control group.Conclusion: The IPC with the pressure of 120 mmHg inside the chambers effectively helps to reduce a phlebolymphedema
Full Text Available Sebastian Wojcinski1, Andre Farrokh1, Ursula Hille2, Jakub Wiskirchen3, Samuel Gyapong1, Amr A Soliman1,4, Friedrich Degenhardt1, Peter Hillemanns21Department of OB/GYN, Franziskus Hospital, Bielefeld, Germany; 2Department of OB/GYN, Hannover Medical School, Hannover, Germany; 3Department of Radiology, Franziskus Hospital, Bielefeld, Germany; 4Department of OB/GYN, Faculty of Medicine, University of Alexandria, Alexandria, EgyptAbstract: The idea of an automated whole breast ultrasound was developed three decades ago. We present our initial experiences with the latest technical advance in this technique, the automated breast volume scanner (ABVS ACUSON S2000TM. Volume data sets were collected from 50 patients and a database containing 23 women with no detectable lesions in conventional ultrasound (BI-RADS®-US 1, 13 women with clearly benign lesions (BI-RADS®-US 2, and 14 women with known breast cancer (BI-RADS®-US 5 was created. An independent examiner evaluated the ABVS data on a separate workstation without any prior knowledge of the patients’ histories. The diagnostic accuracy for the experimental ABVS was 66.0% (95% confidence interval [CI]: 52.9–79.1. The independent examiner detected all breast cancers in the volume data resulting in a calculated sensitivity of 100% in the described setting (95% CI: 73.2%–100%. After the ABVS examination, there were a high number of requests for second-look ultrasounds in 47% (95% CI: 30.9–63.5 of the healthy women (with either a clearly benign lesion or no breast lesions at all in conventional handheld ultrasound. Therefore, the specificity remained at 52.8% (95% CI: 35.7–69.2. When comparing the concordance of the ABVS with the gold standard (conventional handheld ultrasound, Cohen’s Kappa value as an estimation of the inter-rater reliability was κ = 0.37, indicating fair agreement. In conclusion, the ABVS must still be regarded as an experimental technique for breast ultrasound, which
Full Text Available Focus and scope Publication ethics Journal metrics Frequent asked questions Supporting agencies Contact us Reading tools Print this article Indexing metadata Review policy Email this article Email the author Post a Comment Translate content Powered by Translate Related items Show all ✔ Open access ✔ Global visibility ✔ Rapid publication ✔ Quality peer review ✔ Author retains copyright ✔ Personalised service ✔ Submit online Home About Author Reviewer Reader Support Archives Search Home > Vol 70, No 1 (2014 > Urbaniak Original Research Bookmark and Share Freed by trust, to believe together: Pursuing global ecumenism with Küng and Tracy Jakub Urbaniak HTS Teologiese Studies / Theological Studies; Vol 70, No 1 (2014, 9 pages. doi: 10.4102/hts.v70i1.2047 Submitted: 16 August 2013 Published: 11 April 2014 Abstract In the past decades it has emerged more clearly than before that Christian religion, which has so often contributed to human oppression, has rich theological resources that can be used to restore and perfect human freedom. These resources have been reflected upon not only by liberation theologians, but also within the ecumenically oriented theology of religions which targets what Hans Küng calls global responsibility based on global ethics. World religions have an essential role to play in rendering that global humanity more humane and free. The only way to accomplish this task leads through ongoing dialogue, directed both ad intra and ad extra, in the pursuit of a ‘global ecumenism’ which the present suggests and the future demands. For those liberating and unitive resources inherent in religious theory and praxis to be activated, fundamental trust in the reality of the world and of one’s own self appears indispensable. By deepening the theological insights of Hans Küng and David Tracy, the article seeks to explore the mutual correlation between such fundamental trust in reality and religious faith in God, interpreted
meteoroid which fragmented heavily in the atmosphere and produced large numbers of small (under 10 g) meteorites. Nevertheless, some parts of the meteoroid were strong enough, so that a few relatively large (over 1 kg) meteorites exist as well. We were lucky that the three videos and the radiometric curves enabled us to reconstruct the trajectory and atmospheric fragmentation of the Kosice bolide, although the precision is, of course, lower than it would have been from regular meteor cameras. Full details will be published in the paper cited below. I am grateful to many people who collaborated in this work, especially Antal Igaz, Pavel Spurny, Juraj Toth, Pavel Kalenda, Jakub Haloda and Jan Svoren.
Majzlan, Juraj; Berkh, Khulan; Kiefer, Stefan; Koděra, Peter; Fallick, Anthony E.; Chovan, Martin; Bakos, František; Biroň, Adrián; Ferenc, Štefan; Lexa, Jaroslav
In this contribution, we report new data on mineralogy, alteration patterns, geochemistry, fluid properties and source of fluids for the deposit Nová Baňa, one of the smaller epithermal deposits in the Middle Miocene Štiavnica andesite stratovolcano (Western Carpathians, Slovakia). Ore veins and the associated rocks were studied in samples from outcrops and old mines, grab samples, and bore holes from the central part of the deposit (ore structures Althandel, Jozef, Jakub, Vavrinec), northern part (Freischurf), SE part (Gupňa) and SW part (Šibeničný vrch). Pervasive hydrothermal alteration transformed the rock-forming minerals into a mixture of adularia and fine-grained quartz, with lesser amount of pyrite, Ti oxides and Fe oxides. This assemblage was further altered to omnipresent interstratified illite/smectite that was used in this study as a geothermometer, corroborating the results from the fluid inclusion work. Ore minerals comprise predominantly pyrite, sphalerite, galena but all sulfides are relatively sparse in the samples studied. Minerals of precious metals are electrum, Ag-tetrahedrite, acanthite, members of the polybasite-pearceite and pyrargyrite-proustite solid solution, and rare miargyrite, Hg-Ag tetrahedrite, and diaphorite. In the central part, we have found also some stibnite. In the SE part of the deposit, acanthite, uytenbogaardtite, and petrovskaite occur and seem to be related to supergene enrichment of the ores. In bulk ore samples, Zn usually dominates over Pb and Cu. The average Ag:Au ratio for the entire deposit is 64:1. The concentrations of precious metals in the grab samples reach maxima of 50 ppm Au and 570 ppm Ag in the SE part and 116 ppm Au and 1110 ppm Ag in the central part of the deposit. Fluid inclusions show signs of trapping of a heterogeneous fluid. In the central, northern and SE parts of the deposit, homogenization temperatures of 190-260 °C and consistently low salinities of minerals is recalculated to fluid
Mittal, K. C.; Gupta, S. K.
equipments, accessories, products etc by different manufacturers and suppliers has been organized at the venue of the symposium hall for the benefit of the participants. The interest shown by the exhibitors reveals that the industry has come of age and the advances that have taken place over the years is quite significant. During the symposium, the Indian Vacuum Society felicitated two distinguished personalities who have contributed significantly for the development of vacuum science and technology in the country. The C AMBASANKARAN memorial and Smt SHAKUNTALABAI VYAWAHARE memorial Awards were also conferred on the two best contributed papers. A committee constituted by the Symposium Organizing Committee evaluated the relevance, scientific content, and clarity of presentation to decide the award winning papers. It is hoped that the discussion generated by the delegates at the symposium will help in a better understanding vacuum science and technology. K C Mittal Convener S K Gupta Co Convener International Advisory Committee Kakodkar, Anil DAE/India, Chairman Badve, Cdr A.V.(IN Retd.) Pfeiffer Vac India Banerjee, S. BARC/India Bhandari, R.K. BRNS/India Chander, Shekhar CEERI/India Chopra, K.L. IIT Delhi/India Day, Chris ITER Grover, R.B DAE,BARC/India Jakub, Szajman VSA/ Australia Jayaraj, R.N. NFC/India Kamath, H.S. BARC/India Kaw, P.K. IPR/India Kobayashi, M. VSJ/Japan Kumar, Lalit MTRDC, India Kumar, Vikram NPL., India Langley, Robert AVS, USA Larour, Jean Ecole/France Mendonsa, R.H. Lawrence and Mayo Myneni, Ganapatirao Jlab/USA Narsaiah, S.V. HHV Padamsee, Hasan Cornell/USA Pillay, R.G. TIFR Raj, Baldev IGCAR/India Raju, P.T. IVS/India Ramasami, T. DST/India Ray, A.K. BARC/India Reid, RJ IUVSTA/UK Roy, Amit IUAC/india Sahni, V.C. RRCAT, BARC/India Schamiloglu, E. UNM/USA Shankara, K.N. VSSC,ISRO/India Sinha, Bikash VEC,SINP/India Strubin, P. CERN/Switzerland Local Organizing Committee Ray, A.K. BARC (Chairman) Kailas, S. BARC, (Co Chairman) Chakravarty, D.P. BARC
; der Band V - dem polnischen König Stefan Batory; der Band VI /u.d.T. "Asclepius"/ - dem Erzbischof von Lemberg, Dan Dimitrij Solikowski; der Band IX - dem Kanonikus am Krakauer Dom Hieronymus Powodowski. Die übrigen fehlenden Bände /VII, VIII und X/ waren zwar druckfertig, erschienen jedoch nicht, auch die Manuskripte gingen verloren. Die ersten sechs Bände des "Pymander1’ erschienen dann noch einmal 1630 in Köln .in der Offizin des P. Cholinius, mitredigiert von F. Foix de Candal, einem klassischen Philologen. Rosselli stand in seiner Versöhnungsbereitschaft gegenüber anderen Konfessionen Erasmus von Rotterdam sehr nahe. Dennoch stiess er in Krakau auf keinen Widerstand, weder seitens seiner Mitbrüder noch seitens der Krakauer Professoren. Seine Widersacher, wie z.B. Podwodowski oder der Rektor der Universität, Jakub Görski, teilten zwar seine Einstellung nicht, begegnetem ihm aber stets mit grösser Freundlichkeit. Nicht ohne Bedeutung dürfte dabei der Umstand gewesen sein, dass Rosselli im Auftrag des Generalministers der Observanten nach Polen gekommen war und 1585 zum Generalkommissar und Visitator der polnischen Provinz zur Durchführung der tridentinischen Reform ernannt wurde. Im Bereich des Provinzkapitel in Warschau wurde 1585 eine Neuordnung des Studiums beschlossen und mit dem Lehrauf - trag jene Ordensbrüder betraut, die ihr Theologiestudium in Wilna abgeschlossen hatten. Rosselli machte sich einen Namen auch als Prediger. Zwei seiner Predigten sind uns in schriftlicher Form erhalten geblieben, die eine als Manuskript über die Auferstehung Christi aus dem Jahre 1582 /Ossolineum- Bibliothek, Hnds. 229, S. 123-129/, die andere wurde 1590 in Krakau u.d.T. "Oratio fuebralis ... in sepultra Stephani I Regis Poloniae. 1586" veröffentlicht. Die letztere hielt er bei der Bestattungszeremonie des polnischen Königs Bathory. Er soll auch bei der Krönung des Königs Sigismund III Waza gepredigt haben. Aus seiner Feder stammten weiters die uns heute
Pandit, V. S.; Pal, Gautam
clearly indicates that industry has advanced quite significantly. During the symposium, the Indian Vacuum Society honoured two distinguished personalities for their remarkable and significant contributions to the field of vacuum science and development of technology in the country. Awards were presented for both oral and poster papers during the symposium. A committee evaluated the scientific content and clarity of presentation of contributed papers. We believe that deliberations and discussions at the symposium will help gain a better understanding of the complicated and involved technology of vacuum science and be of benefit to scientists and technologists. Subimal Saha Convener Gautam Pal Co-Convener V S Pandit Secretary Surajit Pal Treasurer Conference photograph International Advisory Committee National Advisory Committee S BanerjeeDAE/IndiaR K Bhandari (Chairman)VECC Rockett AngusAVS/USAD L BandyopadhyayIVS A V Dadve CdrPfeiffer Vac /IndiaS B BhattIPR M Barma TIFR/IndiaK G BhushanBARC R K BhandariVECC/IndiaAlok ChakrabartiVECC R C BudhaniNPL, IndiaD P ChakravartyBARC Shekhar ChanderCEERI/IndiaTushar DesaiMumbai Univ S C ChetalIGCAR/IndiaR DeyVECC K L ChopraIIT Delhi/IndiaS C GadkariBARC Christian DayKIT/GermanyS K GuptaIUVSTA/India Kraemer DieterFAIR/GermanyShrikrishna GuptaBARC L M GantayatBARC/IndiaRajendra JatharAgilent Technologies R B GroverDAE, BARC/IndiaS N JoshiCEERI P D Gupta RRCAT/IndiaD KanjilalIUAC Szajman JakubVSA/AustraliaC MallikVECC R N JayarajNFC/IndiaS G MarkandeyaBRNS S KailasBARC/IndiaK C MittalBARC P K KawIPR/IndiaS NagarjunHHV Bangalore Lalit KumarMTRDC/IndiaK G M NairIGCAR Jean Larour Ecole/FranceGautam Pal (Co-convener)VECC Marminga LiaTRIUMF/CanadaSurajit Pal (Treasurer)VECC Shekhar MishraFermilab/USA V S Pandit (Secretary)VECC Ganapatirao MyneniJlab/USaR G PillayTIFR S V NarasaiahHHV/IndiaMohan PradeepNPL K RadhakrishnanISRO/IndiaY Ranga RaoVac Techniques A S Raja RaoIVS/IndiaR RanganathanSINP T RamasamiDST/IndiaSubimal Saha (Convener
Deputies between 1990 and 2013. The relationship between politicians and local people within decision-making process, which is depicted as a consequence of this conflict, is then discussed. Interesting conclusions concern the plurality of dialogue and roles of the actors within it; the influence of scientists on the solutions; and the inflammatory and emotional characteristics of recent debate. As a contrast, which serves as a counterargument to show the power of civic society, Vendula Zahumenská refers to a case in Hradec Králové where environmentalists and local developers have been in conflict concerning the development and commercial use of the Na Plachtě natural monument. This case study shows the role of public participation in environmental protection and describes the specific opportunities for influencing environmental decision-making. But there are cases in CR where declared economic interests are so strong that they eliminate dialogue with civic society – for example, as a result of brown coal mining and its associated industrial development, 106 towns and villages were obliterated in North Bohemia and its population was resettled to newly built prefabricated housing estates. A Case study analysing biographic interviews with the displaced people of Tuchomyšl is presented by Ivana Hermová. The author shows that the former Tuchomyšlers continue to identify strongly with the social space of the obliterated village, and discovers how they reflect on their forced eviction 35 years after the physical destruction of the village. That these conclusions concerning the involvement of social actors might be reflected (and used in the practice of school education, is described by Alois Hynek, Břetislav Svozil, Jakub Trojan and Jan Trávníček. In a reflection on the Deblínsko landscape project these authors refer to the roles of stakeholders including a university, primary school and kindergarten, and also owners, users, decision-makers, shareholders and