WorldWideScience

Sample records for nuclear organization maintain

  1. How Does Nuclear Organization Maintain Normal Mammary Phenotype?

    National Research Council Canada - National Science Library

    Lelievre, Sophie A

    2005-01-01

    .... Using non-neoplastic human breast epithelial S1 cells that differentiate into acini in the presence of extracellular matrix, we have shown a link between the nuclear organization of the protein NuMA...

  2. How Does Nuclear Organization Maintain Normal Mammary Phenotype?

    National Research Council Canada - National Science Library

    Lelievre, Sophie

    2004-01-01

    .... Using non-neoplastic human breast epithelial S1 cells that differentiate into acini in the presence of extracellular matrix, we have shown a link between the nuclear organization of the protein NuMA...

  3. Developing and maintaining nuclear competencies

    International Nuclear Information System (INIS)

    Gobert, C.

    2004-01-01

    The paper discusses the following aspects on the nuclear knowledge management: assimilation of knowledge management, recognition of the nuclear specificity, attracting young talents. Another feature which, possibly, differentiates nuclear from other high-tech industries is that time constraints in some nuclear development may very well exceed the duration of a generation of professionals. That means, not only maintaining scientific and technical knowledge, which, as a minimum, leads to maintain: a rigorous supervision of human resources in quality and quantity; anticipatory planning of human resources, with a special focus on succession planning concerning expertise positions; a steady and continuous effort in training and retraining programs. Maintaining the safety culture is also one of the major managerial duties. Taking full account of the nuclear specificity in knowledge maintenance and development in the AREVA group, requests a multifunctional approach, which combines efforts of Research and Innovation, and Human Resources departments, plus the group Nuclear inspectorate. It is acknowledged that the industry, basically, would readily rely on the capabilities of the academic world and research centers in ensuring that training and education in nuclear science and technologies are attuned to the evolving needs of the industry, in maintaining the proper educational programs and in fostering fruitful cooperations between them

  4. The Centralized Reliability Data Organization (CREDO); an advanced nuclear reactor reliability, availability, and maintainability data bank and data analysis center

    International Nuclear Information System (INIS)

    Knee, H.E.

    1991-01-01

    The Centralized Reliability Data Organization (CREDO) is a data bank and data analysis center, which since 1985 has been jointly sponsored by the US Department of Energy's (US DOE's) Office of Technology Support Programs and Japan's Power Reactor and Nuclear Fuel Development Corporation (PNC). It focuses on reliability, availability and maintainability (RAM) data for components (e.g. valves, pumps, etc.) operating in advanced nuclear reactor facilities. As originally intended, the purpose of the CREDO system was to provide a centralized source of accurate, up-to-date data and information for use in RAM analyses necessary for meeting DOE's data needs in the areas of advanced reactor safety assessments, design and licensing. In particular, creation of the CREDO system was considered an essential element needed to fulfill the DOE Breeder Reactor Safety Program's commitment of 'identifying and exploiting areas in which probabilistic methods can be developed and used in making reactor safety Research and Development choices and optimizing designs of safety systems'. CREDO and its operation are explained. (author)

  5. The Challenges of Maintaining Nuclear Cultures. US and UK Perspectives

    International Nuclear Information System (INIS)

    Brooks, Linton; McKane, Tom

    2016-01-01

    After the world entered the nuclear age, civilian and military organizations have witnessed the slow emergence of nuclear cultures, defined as the set of values and knowledge, shared among the national security community, about the relative importance of nuclear weapons in the country's defense posture, the distinctive features of nuclear weapons in terms of security, safety and operational requirements, and the workings of deterrence. Nuclear cultures have helped to ensure some level of coherence in policy-making and, most importantly, to maintain safe and effective deterrents. At a national level, however, each nuclear culture is confronted with significant challenges, such as generational change, decreasing levels of understanding or attention among the political and military leadership, insufficient funding or a growing inability to meet manpower requirements in both the nuclear weapons complexes and the armed forces. This paper looks at the United States and United Kingdom's recent efforts to maintain their nuclear culture, and at the key challenges these two countries face while pursuing this aim. (authors)

  6. Lamin A and microtubules collaborate to maintain nuclear morphology.

    Science.gov (United States)

    Tariq, Zeshan; Zhang, Haoyue; Chia-Liu, Alexander; Shen, Yang; Gete, Yantenew; Xiong, Zheng-Mei; Tocheny, Claire; Campanello, Leonard; Wu, Di; Losert, Wolfgang; Cao, Kan

    2017-07-04

    Lamin A (LA) is a critical structural component of the nuclear lamina. Mutations within the LA gene (LMNA) lead to several human disorders, most striking of which is Hutchinson-Gilford Progeria Syndrome (HGPS), a premature aging disorder. HGPS cells are best characterized by an abnormal nuclear morphology known as nuclear blebbing, which arises due to the accumulation of progerin, a dominant mutant form of LA. The microtubule (MT) network is known to mediate changes in nuclear morphology in the context of specific events such as mitosis, cell polarization, nucleus positioning and cellular migration. What is less understood is the role of the microtubule network in determining nuclear morphology during interphase. In this study, we elucidate the role of the cytoskeleton in regulation and misregulation of nuclear morphology through perturbations of both the lamina and the microtubule network. We found that LA knockout cells exhibit a crescent shape morphology associated with the microtubule-organizing center. Furthermore, this crescent shape ameliorates upon treatment with MT drugs, Nocodazole or Taxol. Expression of progerin, in LA knockout cells also rescues the crescent shape, although the response to Nocodazole or Taxol treatment is altered in comparison to cells expressing LA. Together these results describe a collaborative effort between LA and the MT network to maintain nuclear morphology.

  7. How to maintain nuclear competence and knowledge management in Europe

    International Nuclear Information System (INIS)

    Comsa, Olivia; Meglea, Claudia; Paraschiva, M. V.; Banutoiu, Maria; Popescu, C.

    2002-01-01

    In the next decades, the tasks in nuclear activities will remain important in Europe irrespective of the different energy options decided by the Member State Governments. Radiation protection, safe nuclear plant operation and nuclear waste management where existing, rely on highly skilled people. There are serious concerns about their replacement from the coming generation. Reasons for concern occur now in several reports. Knowledge Management has evolved from an information technology buzzword, into a domain with a wide spectrum of practical applications in a rapidly growing number of organizations. In the information society, knowledge management techniques are seen as the decisive means in concentrating and preserving a company's knowledge, offering easy and fast access to this knowledge (particularly the experts 'implicit' knowledge as opposed to 'explicit' documents), ensuring its efficient use, thus keeping up the company's competitiveness. The variety of techniques employed by a knowledge management such as knowledge portals for easy access and navigation of the knowledge, document management systems for administration of arbitrary documents formats, content managers with extended classification, search and retrieval capabilities, yellow pages connecting the knowledge domain with the knowledgeable persons in the field, and inclusion of existing databases might help overcome the difficulties which are foreseen for the near future. As a consequence, the chances and benefits offered by knowledge management in the nuclear field should not be neglected. First projects use are under way in several countries to investigate these aspects. An efficient knowledge management should have those coming from other domains to enter easily into the nuclear sector. In the end, however, successful recruitment of skilled nuclear personnel will depend mostly on the attractiveness of the sector. In view of enlargement of the European Union, a major additional aspect is that all

  8. Position paper on maintaining nuclear competence

    International Nuclear Information System (INIS)

    2013-01-01

    The ENS Higher Scientific Council (HSC) is concerned about the current negative developments within some Member States of the EU and the consequential reduced perspectives in the field of nuclear energy technology, education, research and development. The HSC believes that the use of nuclear energy provides an essential contribution to the secure, clean and affordable energy supply for electricity generation, and that this will remain for at least the rest of this century. The HSC, therefore, strongly recommends that within the EU the resources that are allocated to nuclear education and training and to nuclear R and D reflects the increasing globalization of nuclear power and the needs of Member States that will have nuclear power or decommissioning programmes for decades to come. In addition, the HSC recommends that the nuclear industry should actively encourage the setting up of knowledge transfer mechanisms to ensure that the knowledge, know-how and experiences of the current generation of professionals within the industry is not lost to the young people entering nuclear careers. Mobility programmes to support and encourage young professionals to work across the EU to gain wider experience of nuclear power operations should be set up. These activities should help young professionals working in the nuclear technology field to expand long-life networks and business connections and thereby be better prepared for the challenges of the 21 st century. (orig.)

  9. Position paper on maintaining nuclear competence

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-04-15

    The ENS Higher Scientific Council (HSC) is concerned about the current negative developments within some Member States of the EU and the consequential reduced perspectives in the field of nuclear energy technology, education, research and development. The HSC believes that the use of nuclear energy provides an essential contribution to the secure, clean and affordable energy supply for electricity generation, and that this will remain for at least the rest of this century. The HSC, therefore, strongly recommends that within the EU the resources that are allocated to nuclear education and training and to nuclear R and D reflects the increasing globalization of nuclear power and the needs of Member States that will have nuclear power or decommissioning programmes for decades to come. In addition, the HSC recommends that the nuclear industry should actively encourage the setting up of knowledge transfer mechanisms to ensure that the knowledge, know-how and experiences of the current generation of professionals within the industry is not lost to the young people entering nuclear careers. Mobility programmes to support and encourage young professionals to work across the EU to gain wider experience of nuclear power operations should be set up. These activities should help young professionals working in the nuclear technology field to expand long-life networks and business connections and thereby be better prepared for the challenges of the 21{sup st} century. (orig.)

  10. Maintaining non-nuclear weapon status

    International Nuclear Information System (INIS)

    Muller, H.

    1991-01-01

    Among the some 170 sovereign states in the world, five are legally recognized as nuclear weapon states (NWS) under the terms of the 1968 Non-Proliferation Treaty (NPT). Six countries (Argentina, Brazil, India, Israel, Pakistan, and South Africa) are counted as threshold states: they possess sizeable unsafeguarded nuclear facilities or have passed the brink of a nuclear test or of clandestine weapon production. Six other countries (Iran, Iraq, Libya, Taiwan, and North and South Korea) have been suspected periodically of either considering the nuclear weapon option or of working secretly on the development of weapons. Thus, about 150 non-nuclear weapon states (NNWS) remain which neither possess nuclear weapons nor strive to acquire them. These states are distributed throughout the globe and encompass highly industrialized as well as underdeveloped countries, liberal democracies, socialist states, sheikdoms and dictatorships. Some NNWS face acute military threats; other are far removed from the quarrels of the world, as in the case of some remote fortunate islands. Furthermore, NNWS may be members of nuclear-umbrella alliances or may have opted for a policy of neutrality or non-alignment

  11. Maintaining Nuclear Competence within the EU

    International Nuclear Information System (INIS)

    Slugen, V.

    2013-01-01

    In this presentation author deals with the activities of European Nuclear Society in scientific and education areas. Education and scientific orientation in the Slovak University of Technology are reviewed.

  12. Valve maintainability in CANDU-PHW nuclear generating stations

    International Nuclear Information System (INIS)

    Pothier, N.E.; Crago, W.A.

    1977-09-01

    Design, application, layout and administrative factors which affect valve maintainability in CANDU-PHW power reactors are identified and discussed. Some of these are illustrated by examples based on prototype reactor operation experience. Valve maintainability improvements resulting from laboratory development and maintainability analysis, have been incorporated in commercial CANDU-PHW nuclear generating stations. These, also, are discussed and illustrated. (author)

  13. The importance of university research in maintaining the nuclear option

    International Nuclear Information System (INIS)

    Bruschi, H.J.; Hochreiter, L.E.

    1991-01-01

    The role of the university in maintaining and revitalizing the nuclear option should have four goals. First, it must attract highly skilled students who have an interest in math and science and help foster their interest in nuclear science and engineering. Next, it must present a state-of-the-art educational program that contains meaningful research to maintain these students. The third goal of nuclear engineering departments is to provide the nontechnical student a fair assessment of benefits and risks associated with commercial nuclear power relative to other sources of electricity. Lastly, it must effectively communicate to all students a compelling vision of nuclear power as a vital energy resource that will grow. The most difficult role for the university is to successfully convey a future for those in the nuclear science and engineering program

  14. Maintaining Situational Awareness in Large, Complex Organizations

    National Research Council Canada - National Science Library

    Carreno, Jose; Galdorisi, George; Goshorn, Rebekah

    2006-01-01

    .... Another solution, gaining popularity in the business sector, is environmental scanning. Environmental scanning identifies, collects, translates and applies information about external events that influence an organization's strategic landscape...

  15. Teaching and Maintaining Ethical Behavior in a Professional Organization

    OpenAIRE

    Brodhead, Matthew T.; Higbee, Thomas S.

    2012-01-01

    In addition to continuing education mandates by the Behavior Analyst Certification Board (BACB), behavior-analytic professional organizations may adopt systems that teach and maintain ethical behavior in its employees. Systems of ethical supervision and management may allow for an organization to customize training that prevents ethical misconduct by employees. These systems may also allow supervisors to identify ethical problems in their infancy, allowing the organization to mitigate concern...

  16. Teaching and maintaining ethical behavior in a professional organization.

    Science.gov (United States)

    Brodhead, Matthew T; Higbee, Thomas S

    2012-01-01

    In addition to continuing education mandates by the Behavior Analyst Certification Board (BACB), behavior-analytic professional organizations may adopt systems that teach and maintain ethical behavior in its employees. Systems of ethical supervision and management may allow for an organization to customize training that prevents ethical misconduct by employees. These systems may also allow supervisors to identify ethical problems in their infancy, allowing the organization to mitigate concerns before they further develop. Systems of ethical management and supervision also may help to improve services and promote consumer protection. Additional benefits might include both avoiding litigation and loss of consumers and income. These systems may promote the field of Behavior Analysis as a desirable, consumer-friendly approach to solving socially significant behavior problems.

  17. Nuclear energy and international organizations

    International Nuclear Information System (INIS)

    Lindemann, B.

    1975-01-01

    The historical perspectives of the international organizations' role concerning the development and spreading of the peaceful uses of nuclear energy, taking into account the national interests within and towards these organizations, are portrayed. The difference in political status between the so-called nuclear and non-nuclear States, lodged in Articles I and II of the Non-Proliferation Treaty is an important factor. The effects so far of these differences in status on the interest of nuclear States to participate in organizations and on factors which might possibly lead to conflict between these two groups are presented. The author skirts the cooperation between organizations (international bureaucracies, group-formation of states). (HP/LN) [de

  18. Ways to maintain nuclear safety competence in Finland

    International Nuclear Information System (INIS)

    Vanttola, T.; Mattila, L.; Reiman, L.

    2000-01-01

    In mid-1990's, both Finnish nuclear power operators started extensive plant modernization. National surveys indicated that the present age distribution of nuclear power experts implies shortage of resources through retirement within 10 years, unless education is timely enhanced. The current rate of nuclear energy specific education, about 10 master's degrees per year, will be too low, particularly if construction of new nuclear capacity were started. The problem is recognised, and some measures have been initiated. In Finland continued public funding for nuclear energy research is judged important to assure impartial expertise for the safety authorities. This research has been organised as national research programmes, where the requirement to raise experts is emphasised. Challenging tasks have proved to be important in motivating the students and the permanent personnel. The specific features of the VVER reactors, participation in international R and D projects and, recently, design and assessment of ALWR concepts have offered such possibilities. The image of nuclear energy affects the interest of young generation when choosing a career. One way to improve the situation is to increase communication with the public and direct information to the potential students. The need for other than technical skills is also reflected in the latest work programme of the Young Generation Network, organised by the Finnish Nuclear Society. (authors)

  19. Maintaining quality control in a nontraditional nuclear technology degree program

    International Nuclear Information System (INIS)

    DeSain, G.W.

    1989-01-01

    Regents College, created by the Board of Regents of the University of The State on New York in 1971, has been offering, since January 1985, AS and BS degrees in nuclear technology. The impetus for establishing the nuclear technology degrees came from nuclear utility management and had to do with the US Nuclear Regulatory Commission proposed rule regarding degreed operators on shift. There are a variety of ways to earn credits in Regents College degree programs: (1) college courses taken for degree-level credit from regionally accredited colleges; (2) courses sponsored by business, industry, or government that have been evaluated and recommended for credit by the New York National or American Council on Education (ACE's) Program on Noncollegiate Sponsored Instruction (PONSI); (3) military education that has been evaluated by ACE PONSI; (4) approved college-proficiency examinations; and (5) special assessment: an individualized examination of college-level knowledge gained from experience or independent study. Nuclear technology students primarily use college course work, evaluated military education, and proficiency examinations to complete degree programs. However, an increasing number of utilities are having training programs PONSI evaluated, resulting in an increased use of these courses in the nuclear technology degrees. Quality control is a function of several factors described in the paper

  20. Organizing nuclear power plant operation

    International Nuclear Information System (INIS)

    Adams, H.W.; Rekittke, K.

    1987-01-01

    With the preliminary culmination in the convoy plants of the high standard of engineered safeguards in German nuclear power plants developed over the past twenty years, the interest of operators has now increasingly turned to problems which had not been in the focus of attention before. One of these problems is the organization of nuclear power plant operation. In order to enlarge the basis of knowledge, which is documented also in the rules published by the Kerntechnischer Ausschuss (Nuclear Technology Committee), the German Federal Minister of the Interior has commissioned a study of the organizational structures of nuclear power plants. The findings of that study are covered in the article. Two representative nuclear power plants in the Federal Republic of Germany were selected for the study, one of them a single-unit plant run by an independent operating company in the form of a private company under German law (GmbH), the other a dual-unit plant operated as a dependent unit of a utility. The two enterprises have different structures of organization. (orig.) [de

  1. Organization of nuclear regulatory activities

    International Nuclear Information System (INIS)

    Blidaru, Valentin

    2008-01-01

    The paper presents the structure, missions and organizational aspects of the CNCAN, the National Commission for the control of nuclear activities in Romania. The paper addresses the following main issues: 1.General aspects; 2.Organizational structure of the NRA in Romania; 3.General description of the Division for Nuclear Safety Assessments; 4.Specific activities; 5.Regulatory approaches and practices. Under the title of 'General aspects' the following three basic statements are highlighted: 1.CNCAN is a governmental organization responsible for the development of the regulatory framework, the control of its implementation and the licensing of nuclear facilities; 2.CNCAN is the national authority competent in exercising the regulatory activity, authorization and control in the nuclear field provided by the law No. 111/ 1996 republished in 1998; 3.The Commission exercises its functions independently of the ministries and other authorities of the public control administration being subordinated to the Romanian Government. The organizational structure is as follows: - President, the Managerial Council and the Advisory Council coordinating the four General Divisions that are responsible for: - Nuclear Safety with Division of Nuclear Safety Assessment and Division of Nuclear Objectives Surveillance; - Radiological Safety with Division of Radiological Safety Assessment and Division of Operational Radiation Protection; - Surveillance of Environmental Radioactivity with Division of Assessment and Analysis and Division of National Network; - Development and Resource with the Division of Economy and Division of Human Resources. In addition under direct coordination of the President operate the Division of Radiation Protection, Transport and Radioactive Waste and the Division of International Cooperation and Communication. Specific activities are listed describing among others the issues of: - Safety of nuclear installation; - Evaluation relating to licensing of nuclear

  2. International and national organizations within nuclear energy

    International Nuclear Information System (INIS)

    Sandstroem, S.

    1975-03-01

    A survey is given of the organization, objective and action of international and national organizations working with nuclear energy. Five types of organizations are treated: international governmental organizations, international non-governmental organizations, international organizations dealing with ionizing radiation, nordic organizations, and Swedish organizations. Special attention is payed to the Swedish participation in the different organizations. (K.K)

  3. Nuclear power and sustainable development. Maintaining and increasing the overall assets available to future generations

    International Nuclear Information System (INIS)

    2002-01-01

    A central goal of sustainable development is to maintain or increase the overall assets available to future generations, while minimizing consumption of finite resources and not exceeding the carrying capacities of ecosystems. The development of nuclear power broadens the natural resource base usable for energy production, increases human and man-made capital, and, when safely handled, has little impact on ecosystems. Energy is essential for sustainable development. With continuing population and economic growth, and increasing needs in the developing world, substantially greater energy demand is a given, even taking into account continuing and accelerated energy efficiency and intensity improvements. Today, nuclear power is mostly utilized in industrialized countries that have the necessary technological, institutional and financial resources. Many of the industrialized countries that are able and willing to use nuclear power are also large energy consumers. Nuclear power currently generates 16% of the world's electricity. It produces virtually no sulfur dioxide, particulates, nitrogen oxides, volatile organic compounds or greenhouse gases. Globally, nuclear power currently avoids approximately 600 million tonnes of carbon emissions annually, about the same as hydropower. The 600 MtC avoided by nuclear power equals 8% of current global greenhouse gases emissions. In the OECD countries, nuclear power has for 35 years accounted for most of the reduction in the carbon intensity per unit of delivered energy. Existing operating nuclear power plants (NPPs) for which initial capital investments are largely depreciated are also often the most cost-effective way to reduce carbon emissions from electricity generation. In fact in the United States in 2000, NPPs were the most cost-effective way to generate electricity, irrespective of avoided carbon emissions. In other countries the advantages of existing nuclear generating stations are also increasingly recognized. Interest

  4. The role of international atomic energy agency in maintaining nuclear safety competence

    International Nuclear Information System (INIS)

    Aro, I.; Mazour, T.

    2000-01-01

    This paper provides information how International Atomic Energy Agency can assist Member States in maintaining and developing nuclear safety competence. The topics covered include the development of safety standards, organisation of nuclear safety related conferences, provision of safety reviews, organisation of training courses and topical workshops and publication of training related documents. Usefulness of these activities for competence development is discussed. (author)

  5. Building and Maintaining Healthy Organizations: The Key to Future Success

    National Research Council Canada - National Science Library

    Matthews, Lloyd J

    2000-01-01

    ...." In recognition that there are certain commonalities among all organizational, institutional, and bureaucratic entities, whether civilian or military, the symposium construed the term organization in the broadest way...

  6. Safety culture in the nuclear versus non-nuclear organization

    Energy Technology Data Exchange (ETDEWEB)

    Haber, S.B.; Shurberg, D.A.

    1996-10-01

    The importance of safety culture in the safe and reliable operation of nuclear organizations is not a new concept. The greatest barriers to this area of research are twofold: (1) the definition and criteria of safety culture for a nuclear organization and (2) the measurement of those attributes in an objective and systematic fashion. This paper will discuss a proposed resolution of those barriers as demonstrated by the collection of data across nuclear and non-nuclear facilities over a two year period.

  7. Safety culture in the nuclear versus non-nuclear organization

    International Nuclear Information System (INIS)

    Haber, S.B.; Shurberg, D.A.

    1996-01-01

    The importance of safety culture in the safe and reliable operation of nuclear organizations is not a new concept. The greatest barriers to this area of research are twofold: (1) the definition and criteria of safety culture for a nuclear organization and (2) the measurement of those attributes in an objective and systematic fashion. This paper will discuss a proposed resolution of those barriers as demonstrated by the collection of data across nuclear and non-nuclear facilities over a two year period

  8. The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes.

    Science.gov (United States)

    Fan, Hui; Lv, Pin; Huo, Xiangru; Wu, Jicheng; Wang, Qianfeng; Cheng, Lu; Liu, Yun; Tang, Qi-Qun; Zhang, Ling; Zhang, Feng; Zheng, Xiaoqi; Wu, Hao; Wen, Bo

    2018-02-01

    Eukaryotic chromosomes are folded into higher-order conformations to coordinate genome functions. In addition to long-range chromatin loops, recent chromosome conformation capture (3C)-based studies have indicated higher levels of chromatin structures including compartments and topologically associating domains (TADs), which may serve as units of genome organization and functions. However, the molecular machinery underlying these hierarchically three-dimensional (3D) chromatin architectures remains poorly understood. Via high-throughput assays, including in situ Hi-C, DamID, ChIP-seq, and RNA-seq, we investigated roles of the Heterogeneous Nuclear Ribonucleoprotein U (HNRNPU), a nuclear matrix (NM)-associated protein, in 3D genome organization. Upon the depletion of HNRNPU in mouse hepatocytes, the coverage of lamina-associated domains (LADs) in the genome increases from 53.1% to 68.6%, and a global condensation of chromatin was observed. Furthermore, disruption of HNRNPU leads to compartment switching on 7.5% of the genome, decreases TAD boundary strengths at borders between A (active) and B (inactive) compartments, and reduces chromatin loop intensities. Long-range chromatin interactions between and within compartments or TADs are also significantly remodeled upon HNRNPU depletion. Intriguingly, HNRNPU mainly associates with active chromatin, and 80% of HNRNPU peaks coincide with the binding of CTCF or RAD21. Collectively, we demonstrated that HNRNPU functions as a major factor maintaining 3D chromatin architecture, suggesting important roles of NM-associated proteins in genome organization. © 2018 Fan et al.; Published by Cold Spring Harbor Laboratory Press.

  9. Maintaining knowledge, training and infrastructure for research and development in nuclear safety - INSAG-16. A report by the International Nuclear Safety Advisory Group

    International Nuclear Information System (INIS)

    2003-01-01

    The purpose of this report is to emphasize the importance of maintaining capabilities for nuclear research and education, especially with regard to safety aspects, so that nuclear safety may be maintained in IAEA Member States, and to alert Member States to the potential for significant harm if the infrastructure for research, development and education is not maintained. If the infrastructure for nuclear safety is not maintained, there will be a steady decrease in expertise, and thus in capability to respond to new challenges. The lead time in developing replacement educational opportunities is very long, because most institutions will require an indication of the number of enthusiastic potential students before investing in new infrastructure, and potential students may look elsewhere in the absence of an exciting analytical and experimental programme and a growing career field. Once lost, it would require massive inputs of resources from many IAEA Member States to attempt to re-establish the infrastructure, as was done to establish it when nuclear technology was new. The result could be a downward spiral in which expertise is lost, influence of the technical community on the decision making process is diminished, and complacency, fed by diminished technical capability, begins to exert a strong effect. In view of the above, INSAG has the following recommendations: In order to maintain and further enhance the safety of nuclear facilities and to protect workers and the public and the environment from radiological consequences, the infrastructure for safety research (experimental facilities, highly competent staff and modern analytical tools) must be maintained and supported by the responsible governmental organizations as well as by the operating organizations and manufacturers. This support should include international networking and co-operation, including joint funding of centres of excellence that have facilities and equipment for use in nuclear research

  10. Maintaining knowledge, training and infrastructure for research and development in nuclear safety. INSAG-16. A report by the International Nuclear Safety Advisory Group (Russian Edition)

    International Nuclear Information System (INIS)

    2015-01-01

    The purpose of this report is to emphasize the importance of maintaining capabilities for nuclear research and education, especially with regard to safety aspects, so that nuclear safety may be maintained in IAEA Member States, and to alert Member States to the potential for significant harm if the infrastructure for research, development and education is not maintained. If the infrastructure for nuclear safety is not maintained, there will be a steady decrease in expertise, and thus in capability to respond to new challenges. The lead time in developing replacement educational opportunities is very long, because most institutions will require an indication of the number of enthusiastic potential students before investing in new infrastructure, and potential students may look elsewhere in the absence of an exciting analytical and experimental programme and a growing career field. Once lost, it would require massive inputs of resources from many IAEA Member States to attempt to re-establish the infrastructure, as was done to establish it when nuclear technology was new. The result could be a downward spiral in which expertise is lost, influence of the technical community on the decision making process is diminished, and complacency, fed by diminished technical capability, begins to exert a strong effect. In view of the above, INSAG has the following recommendations: In order to maintain and further enhance the safety of nuclear facilities and to protect workers and the public and the environment from radiological consequences, the infrastructure for safety research (experimental facilities, highly competent staff and modern analytical tools) must be maintained and supported by the responsible governmental organizations as well as by the operating organizations and manufacturers. This support should include international networking and co-operation, including joint funding of centres of excellence that have facilities and equipment for use in nuclear research

  11. Building and Maintaining Healthy Organizations: The Key to Future Success

    National Research Council Canada - National Science Library

    Matthews, Lloyd J

    2000-01-01

    .... Symposium discussions addressed four major thematic areas: establishing values-based organizations, creating a change-receptive organizational culture, attracting and retaining future leaders, and selecting and developing the best leaders...

  12. Human factors design guidelines for maintainability of Department of Energy nuclear facilities

    International Nuclear Information System (INIS)

    Bongarra, J.P. Jr.; VanCott, H.P.; Pain, R.F.; Peterson, L.R.; Wallace, R.I.

    1985-01-01

    Intent of these guidelines is to provide design and design review teams of DOE nuclear facilities with human factors principles to enhance the design and aid in the inspection of DOE nuclear facilities, systems, and equipment. These guidelines are concerned with design features of DOE nuclear facilities which can potentially affect preventive and corrective maintenance of systems within DOE nuclear facilities. Maintenance includes inspecting, checking, troubleshooting, adjusting, replacing, repairing, and servicing activities. Other factors which influence maintainability such as repair and maintenance suport facilities, maintenance information, and various aspects of the environment are also addressed

  13. Human factors design guidelines for maintainability of Department of Energy nuclear facilities

    Energy Technology Data Exchange (ETDEWEB)

    Bongarra, J.P. Jr.; VanCott, H.P.; Pain, R.F.; Peterson, L.R.; Wallace, R.I.

    1985-06-18

    Intent of these guidelines is to provide design and design review teams of DOE nuclear facilities with human factors principles to enhance the design and aid in the inspection of DOE nuclear facilities, systems, and equipment. These guidelines are concerned with design features of DOE nuclear facilities which can potentially affect preventive and corrective maintenance of systems within DOE nuclear facilities. Maintenance includes inspecting, checking, troubleshooting, adjusting, replacing, repairing, and servicing activities. Other factors which influence maintainability such as repair and maintenance suport facilities, maintenance information, and various aspects of the environment are also addressed.

  14. Emotional intelligence skills for maintaining social networks in healthcare organizations.

    Science.gov (United States)

    Freshman, Brenda; Rubino, Louis

    2004-01-01

    For healthcare organizations to survive in these increasingly challenging times, leadership and management must face mounting interpersonal concerns. The authors present the boundaries of internal and external social networks with respect to leadership and managerial functions: Social networks within the organization are stretched by reductions in available resources and structural ambiguity, whereas external social networks are stressed by interorganizational competitive pressures. The authors present the development of emotional intelligence skills in employees as a strategic training objective that can strengthen the internal and external social networks of healthcare organizations. The authors delineate the unique functions of leadership and management with respect to the application of emotional intelligence skills and discuss training and future research implications for emotional intelligence skill sets and social networks.

  15. Nuclear organizations in France - USA - Japan

    International Nuclear Information System (INIS)

    David, J.L.

    1996-01-01

    After an history of the nuclear events of the post-war period in the world, the nuclear organization in three different countries is developed. First, the case of France is described with a chronological account of events, as well as the intern and international laws. Then, the importance of nuclear energy in the electricity production in the USA is put forward. Finally, the nuclear organization in Japan is presented in the same way. (TEC). 4 figs., 1 tab

  16. ANSTO: Australian Nuclear Science and Technology Organization

    International Nuclear Information System (INIS)

    1989-01-01

    The Australian Nuclear Science and Technology Organization conducts or is engaged in collaborative research and development in the application of nuclear science and associated technology. Through its Australian radio-isotopes unit, it markets radioisotopes, their products and other services for nuclear medicine industry and research. It also operates national nuclear facilities ( HIFAR and Moata research reactors), promote training, provide advice and disseminates information on nuclear science and technology. The booklet briefly outlines these activities. ills

  17. Recommendations to the NRC on human engineering guidelines for nuclear power plant maintainability

    Energy Technology Data Exchange (ETDEWEB)

    Badalamente, R.V.; Fecht, B.A.; Blahnik, D.E.; Eklund, J.D.; Hartley, C.S.

    1986-03-01

    This document contains human engineering guidelines which can enhance the maintainability of nuclear power plants. The guidelines have been derived from general human engineering design principles, criteria, and data. The guidelines may be applied to existing plants as well as to plants under construction. They apply to nuclear power plant systems, equipment and facilities, as well as to maintenance tools and equipment. The guidelines are grouped into seven categories: accessibility and workspace, physical environment, loads and forces, maintenance facilities, maintenance tools and equipment, operating equipment design, and information needs. Each chapter of the document details specific maintainability problems encountered at nuclear power plants, the safety impact of these problems, and the specific maintainability design guidelines whose application can serve to avoid these problems in new or existing plants.

  18. Recommendations to the NRC on human engineering guidelines for nuclear power plant maintainability

    International Nuclear Information System (INIS)

    Badalamente, R.V.; Fecht, B.A.; Blahnik, D.E.; Eklund, J.D.; Hartley, C.S.

    1986-03-01

    This document contains human engineering guidelines which can enhance the maintainability of nuclear power plants. The guidelines have been derived from general human engineering design principles, criteria, and data. The guidelines may be applied to existing plants as well as to plants under construction. They apply to nuclear power plant systems, equipment and facilities, as well as to maintenance tools and equipment. The guidelines are grouped into seven categories: accessibility and workspace, physical environment, loads and forces, maintenance facilities, maintenance tools and equipment, operating equipment design, and information needs. Each chapter of the document details specific maintainability problems encountered at nuclear power plants, the safety impact of these problems, and the specific maintainability design guidelines whose application can serve to avoid these problems in new or existing plants

  19. Promoting a learning culture to maintain the nuclear safety competence of AECB staff

    International Nuclear Information System (INIS)

    Omar, A.; Belisle, N.; Grant, I.

    2000-01-01

    In the Canadian regulatory approach, the safe operation of a nuclear installation is primarily the responsibility of the operator. The mission of the Atomic Energy Control Board (AECB) is to ensure that the use of nuclear energy does not pose unnecessary risk to workers, the general public and the environment. The AECB fulfills this responsibility through a comprehensive licensing framework in which compliance with regulatory standards and requirements is assured through systematic safety assessments, inspection and enforcement. These responsibilities require regulatory staff with specialized academic backgrounds and work experience related to the industry. In the past, the AECB readily attracted and retained the qualified personnel needed to ensure nuclear safety competence. However, several factors are now altering this situation. Anticipated retirement in the years ahead among the current generation of staff will result in significant losses of corporate knowledge and experience. In addition, the stagnation of the domestic nuclear power industry has impacted significantly on the recruitment of suitably qualified replacement candidates. Many Canadian universities have had to reduce their nuclear programmes as fewer undergraduate and postgraduate students choose a nuclear career option. In these circumstances, maintaining the AECB's nuclear safety competence requires a more systematic and deliberate approach. This paper describes the measures that the AECB has taken and is planning to take to promote a learning environment, and to assist staff in establishing and maintaining their knowledge and skills. (author)

  20. Quality assurance organization for nuclear power plants

    International Nuclear Information System (INIS)

    1983-01-01

    This Safety Guide provides requirements, recommendations and illustrative examples for structuring, staffing and documenting the organizations that perform activities affecting quality of a nuclear power plant. It also provides guidance on control of organization interfaces, and establishment of lines for direction, communication and co-ordination. The provisions of this Guide are applicable to all organizations participating in any of the constituent areas of activities affecting quality of a nuclear power plant, such as design, manufacture, construction, commissioning and operation

  1. Maintaining knowledge, training and infrastructure for research and development in nuclear safety. A note by the International Nuclear Safety Advisory Group

    International Nuclear Information System (INIS)

    International Nuclear Safety Advisory Group

    2001-01-01

    The purpose of this INSAG Note is to emphasize the importance of maintaining capabilities for nuclear research and education, especially with regard to safety aspects, so that nuclear safety may be maintained in IAEA Member States, and to alert Member States to the potential for significant harm if the infrastructure for research, development and education is not maintained

  2. Religious organizations debate nuclear energy

    International Nuclear Information System (INIS)

    Dowell, T.

    1984-08-01

    This paper reviews the history of the religious debate on nuclear energy over the last thirty years. In the 1950s, religious statements recognized the peaceful uses of atomic energy as a blessing from God and called upon world leaders to promote its use. Nuclear energy programmes were launched in this decade. In the 1960s, there was still religious approval of nuclear energy, but questions about ethics arose. It was not until the 1970s, after the oil crisis, that serious questioning and criticism of nuclear energy emerged. This was particularly true in the United States, where the majority of statements originated - especially in 1979, the year of the Three Mile Island accident. Around this time, the World Council of Churches developed the concept of the just, participatory and sustainable society. The meaning and use of these terms in the nuclear energy debate is examined. This paper also compares the balanced debate of the World Council with the case against the plutonium economy prepared by the National Council of the Churches of Christ in the USA. Three religious statements from the 1980s are examined. A United Church of Canada resolution, critical of nuclear energy, is compared with a favourable report from the Methodist Church in England. Both use similar values: in one case, justice, participation and sustainability; in the other case, concern for others, participation and stewardship. There are not many Catholic statements on nuclear energy. One which is cautious and favourable is examined in detail. It is concluded that the use of concepts of justice, participation and sustainability (or their equivalents) has not clarified the nuclear debate

  3. Activities to maintain, strengthen and hand down the nuclear technology base

    International Nuclear Information System (INIS)

    Uchida, Makoto; Oketani, Koichiro

    2009-01-01

    The recent worldwide 'Nuclear Renaissance' is encouraging the globalization of our nuclear business and making us aware of the increasing importance of the human education and trainings for it. The basic concept of MHI's human resource development and its improvement is 'The improvement in the skills and motivation of each employee leads to the strengthening of the company-wide technology base'. Under this concept we are improving our job efficiency continuously by means of information technology, institutionalizing the means to improve the individual skills and motivation and investing for the effective succession of the skills. In order to take real advantage of those efforts for maintaining, strengthening and effectively handing down the nuclear technology base, it is imperative to keep the volume of actual jobs. So, we have to keep in mind that having actual business continuously is extremely important to keep the sound and solid technology base. (author)

  4. MHI's activities to maintain, strengthen and hand down the nuclear technology base

    International Nuclear Information System (INIS)

    Suzuki, Shigemitsu; Kanda, Makoto; Oketani, Koichiro; Hamasaki, Manabu; Uchida, Makoto

    2008-01-01

    The recent worldwide 'Nuclear Renaissance' is encouraging the globalization of our nuclear business and making us aware of the increasing importance of the human education and trainings for it. The basic concept of MHI's human resource development and its improvement is 'The improvement in the skills and motivation of each employee leads to the strengthening of the company-wide technology base'. Under this concept we are improving our job efficiency continuously by means of information technology, institutionalizing the means to improve the individual skills and motivation and investing for the effective succession of the skills. In order to take real advantage of those efforts for maintaining, strengthening and effectively handing down the nuclear technology base, it is imperative to keep the volume of actual jobs. So, we have to keep in mind that having actual business continuously is extremely important to keep the sound and solid technology base. (author)

  5. Training Activities to Maintain Competences in Nuclear Safety and Security: A Case Study of the Belgian Nuclear Research Centre

    International Nuclear Information System (INIS)

    Kesteloot, N.; Clarijs, T.; Coeck, M.; Vermeersch, F.

    2016-01-01

    Full text: The Belgian Nuclear Research Centre, SCK•CEN, is one of the largest research centers in Belgium. More than 700 employees advance research into nuclear energy and ionizing radiation for civilian use, and develop nuclear technologies for socially valuable purposes. Next to independent fundamental and applied research SCK-CEN provides advice, training, services and products. This paper describes the general approach towards the continuous professional development of all SCK-CEN personnel. The objective of these training activities is to maintain and increase the required competences, in order to optimize the output and the wellbeing on the work floor. Given the nature of the SCK-CEN activities, special attention is given to themes like radiation protection, security and industrial safety. A combination of classical face-to-face training, e-learning and on-the-job training is offered during the onboarding and further career path of an SCK-CEN employee. (author

  6. Maintaining the design integrity of nuclear installations throughout their operating life. INSAG-19. A report by the International Nuclear Safety Advisory Group

    International Nuclear Information System (INIS)

    2003-01-01

    A nuclear power plant design is the product of the activities of many organizations, and changes to that design will occur continuously over the plant's lifetime. Reactor plants are designed to operate for a long period of time, typically 40 years, which may be extended for several decades. This period of time spans several working lifetimes of the staff of the plant, and its length represents a very specific challenge to safety and to the corporate asset management of the enterprise. It also implies that the vendor structure required to support the plant can be expected to change substantially during the plant's lifetime. this INSAG report discusses the problem of maintaining the integrity of design of a nuclear power plant over its entire lifetime in order to achieve a continuous high level of safety. A nuclear power plant design is the product of the activities of many organizations, and changes to that design will occur continuously over the plant's operating lifetime. Reactor plants are designed to operate for a long period of time, typically 40 years, which may be extended for several decades. This period of time spans several working lifetimes of the staff of the plant, and its length represents a very specific challenge to safety and to the corporate asset management of the enterprise. It also implies that the vendor structure required to support the plant can be expected to change substantially during the plant's lifetime. The purpose of this report is to identify the issues and some of the principles that should be addressed, discuss some of the solutions to the problem, and highlight the specific responsibilities of designers, operators and regulators. The issues and principles discussed here are also applicable to other nuclear installations (for example, research reactors and fuel cycle facilities). This INSAG report is directed at senior executives who are responsible for: the overall safety of nuclear installations; the operation, maintenance and

  7. World Health Organization on nuclear power

    International Nuclear Information System (INIS)

    Anon.

    1977-01-01

    A report published by the World Health Organization in cooperation with, and at the instigation of, the Belgian authorities, is summarised. The report was prepared by an international multidisciplinary working group, and concentrated on the somatic and genetic risks from ionising radiation, the environmental effects of nuclear power from the mining of uranium to the disposal of waste and the probability and consequences of accidents, sabotage and theft of nuclear materials. In general positive to nuclear power, the report nevertheless recommends for RESEARCH AND EVALUATION IN SEVERAL SECTORS: The duties of the authorities in providing full and open information on the consequences of the exploitation of nuclear power are emphasised. (JIW)

  8. Risk management of knowledge loss in nuclear industry organizations

    International Nuclear Information System (INIS)

    2006-07-01

    Maintaining nuclear competencies in the nuclear industry and nuclear regulatory authorities will be one of the most critical challenges in the near future. As many nuclear experts around the world are retiring, they are taking with them a substantial amount of knowledge and corporate memory. The loss of such employees who hold knowledge critical to either operations or safety poses a clear internal threat to the safe and reliable operation of nuclear facilities. This publication is intended for senior and middle level managers of nuclear industry operating organizations and provides practical information on knowledge loss risk management. The information provided in this it is based upon the actual experiences of Member State operating organizations and is intended to increase awareness of the need to: develop a strategic approach and action plans to address the potential loss of critical knowledge and skills; provide processes and in conducting risk assessments to determine the potential for loss of critical knowledge caused by the loss of experienced workers; and enable nuclear organizations to utilize this knowledge to improve the skill and competence of new and existing workers In 2004, the IAEA published a report entitled The Nuclear Power Industry's Ageing Workforce: Transfer of Knowledge to the Next Generation (IAEA-TECDOC-1399). That report highlighted some of the knowledge management issues in Member States resulting from the large number of retiring nuclear power plant personnel who had been involved with the commissioning and initial operation of nuclear power plants. This publication complements that report by providing a practical methodology on knowledge loss risk management as one element of an overall strategic approach to workforce management which includes work force planning, recruitment, training, leadership development and knowledge retention

  9. Nuclear Criticality Safety Organization training implementation. Revision 4

    Energy Technology Data Exchange (ETDEWEB)

    Carroll, K.J.; Taylor, R.G.; Worley, C.A.

    1997-05-19

    The Nuclear Criticality Safety Organization (NCSO) is committed to developing and maintaining a staff of qualified personnel to meet the current and anticipated needs in Nuclear Criticality Safety (NCS) at the Oak Ridge Y-12 Plant. This document provides a listing of the roles and responsibilities of NCSO personnel with respect to training and details of the Training Management System (TMS) programs, Mentoring Checklists and Checksheets, as well as other documentation utilized to implement the program. This Training Implementation document is applicable to all technical and managerial NCSO personnel, including temporary personnel, sub-contractors and/or LMES employees on loan to the NCSO, who are in a qualification program.

  10. Nuclear Criticality Safety Organization training implementation. Revision 4

    International Nuclear Information System (INIS)

    Carroll, K.J.; Taylor, R.G.; Worley, C.A.

    1997-01-01

    The Nuclear Criticality Safety Organization (NCSO) is committed to developing and maintaining a staff of qualified personnel to meet the current and anticipated needs in Nuclear Criticality Safety (NCS) at the Oak Ridge Y-12 Plant. This document provides a listing of the roles and responsibilities of NCSO personnel with respect to training and details of the Training Management System (TMS) programs, Mentoring Checklists and Checksheets, as well as other documentation utilized to implement the program. This Training Implementation document is applicable to all technical and managerial NCSO personnel, including temporary personnel, sub-contractors and/or LMES employees on loan to the NCSO, who are in a qualification program

  11. Nuclear Criticality Safety Organization qualification program. Revision 4

    International Nuclear Information System (INIS)

    Carroll, K.J.; Taylor, R.G.; Worley, C.A.

    1997-01-01

    The Nuclear Criticality Safety Organization (NCSO) is committed to developing and maintaining a staff of highly qualified personnel to meet the current and anticipated needs in Nuclear Criticality Safety (NCS) at the Oak Ridge Y-12 Plant. This document defines the Qualification Program to address the NCSO technical and managerial qualification as required by the Y-12 Training Implementation Matrix (TIM). It is implemented through a combination of LMES plant-wide training courses and professional nuclear criticality safety training provided within the organization. This Qualification Program is applicable to technical and managerial NCSO personnel, including temporary personnel, sub-contractors and/or LMES employees on loan to the NCSO, who perform the NCS tasks or serve NCS-related positions as defined in sections 5 and 6 of this program

  12. The operating organization for nuclear power plants. Safety guide

    International Nuclear Information System (INIS)

    2004-01-01

    This Safety Guide was prepared under the IAEA programme for safety standards for nuclear power plants. The present publication is a revision of the IAEA Safety Guide on Management of Nuclear Power Plants for Safe Operation issued in 1984. It supplements Section 2 of the Safety Requirements publication on Safety of Nuclear Power Plants: Operation. Nuclear power technology is different from the customary technology of power generation from fossil fuel and by hydroelectric means. One major difference between the management of nuclear power plants and that of conventional generating plants is the emphasis that should be placed on nuclear safety, quality assurance, the management of radioactive waste and radiological protection, and the accompanying national regulatory requirements. This Safety Guide highlights the important elements of effective management in relation to these aspects of safety. The attention to be paid to safety requires that the management recognize that personnel involved in the nuclear power programme should understand, respond effectively to, and continuously search for ways to enhance safety in the light of any additional requirements socially and legally demanded of nuclear energy. This will help to ensure that safety policies that result in the safe operation of nuclear power plants are implemented and that margins of safety are always maintained. The structure of the organization, management standards and administrative controls should be such that there is a high degree of assurance that safety policies and decisions are implemented, safety is continuously enhanced and a strong safety culture is promoted and supported. The objective of this publication is to guide Member States in setting up an operating organization which facilitates the safe operation of nuclear power plants to a high level internationally. The second objective is to provide guidance on the most important organizational elements in order to contribute to a strong safety

  13. The operating organization for nuclear power plants. Safety guide

    International Nuclear Information System (INIS)

    2005-01-01

    This Safety Guide was prepared under the IAEA programme for safety standards for nuclear power plants. The present publication is a revision of the IAEA Safety Guide on Management of Nuclear Power Plants for Safe Operation issued in 1984. It supplements Section 2 of the Safety Requirements publication on Safety of Nuclear Power Plants: Operation. Nuclear power technology is different from the customary technology of power generation from fossil fuel and by hydroelectric means. One major difference between the management of nuclear power plants and that of conventional generating plants is the emphasis that should be placed on nuclear safety, quality assurance, the management of radioactive waste and radiological protection, and the accompanying national regulatory requirements. This Safety Guide highlights the important elements of effective management in relation to these aspects of safety. The attention to be paid to safety requires that the management recognize that personnel involved in the nuclear power programme should understand, respond effectively to, and continuously search for ways to enhance safety in the light of any additional requirements socially and legally demanded of nuclear energy. This will help to ensure that safety policies that result in the safe operation of nuclear power plants are implemented and that margins of safety are always maintained. The structure of the organization, management standards and administrative controls should be such that there is a high degree of assurance that safety policies and decisions are implemented, safety is continuously enhanced and a strong safety culture is promoted and supported. The objective of this publication is to guide Member States in setting up an operating organization which facilitates the safe operation of nuclear power plants to a high level internationally. The second objective is to provide guidance on the most important organizational elements in order to contribute to a strong safety

  14. Organic analyses of mixed nuclear wastes

    International Nuclear Information System (INIS)

    Toste, A.P.; Lucke, R.B.; Lechner-Fish, T.J.; Hendren, D.J.; Myers, R.B.

    1987-04-01

    Analytical methods are being developed for the organic analysis of nuclear wastes. Our laboratory analyzed the organic content of three commercial wastes and an organic-rich, complex concentrate waste. The commercial wastes contained a variety of hydrophobic and hydrophilic organics, at concentrations ranging from nanomolar to micromolar. Alkyl phenols, chelating and complexing agents, as well as their degradation products, and carboxylic acids were detected in the commercial wastes. The complex concentrate waste contained chelating and complexing agents, as well as numerous degradation products, at millimolar concentrations. 75.1% of the complex concentrate waste's total organic carbon content has been identified. The presence of chelator fragments in all of the wastes analyzed, occasionally at elevated concentrations, indicates that organic diagenesis, or degradation, in nuclear wastes is both widespread and quite vigorous. 23 refs., 3 tabs

  15. Maintaining a balanced electricity supply favours increased nuclear capacity in Finland

    International Nuclear Information System (INIS)

    Ahti, Toivola

    2001-01-01

    Finland's electricity supply is based on a balanced mix of energy sources to maximize the security of supply and to keep the volatility of electricity price at a minimum. One third of electricity is obtained from domestic sources hydro, wood and peat. Nuclear power provides one quarter and fossil fuels slightly over one fifth. Electricity imports from neighbour countries cover the rest of the consumption. It is important to maintain this balanced structure also when electricity supply is being increased. Domestic renewable sources are not enough to cover the predicted future needs, and increasing imports would risk the security of supply. Increasing the proportion of fossil fuels is not a generally desired option. Therefore, balanced increase of nuclear capacity has to be included among the choices of future electricity generation. (author)

  16. Establishing a code of ethics for nuclear operating organizations

    International Nuclear Information System (INIS)

    2007-01-01

    The IAEA Technical Working Group on Training and Qualification of Nuclear Power Plant Personnel (TWG-T and Q) recommended that the IAEA develop a publication on improving the performance of nuclear facility operating organizations through focusing on the ethics and professionalism of personnel at all levels of such organizations. This publication has been prepared in response to that recommendation. The TWG-T and Q made its recommendation based upon an understanding that an organization's code of ethics should apply to behaviours at all levels of the organization; from the Board Room to the working level. The TWG-T and Q also recognized that having the technical competencies related to nuclear technology is not enough to ensure that an operating organization's performance is at the high standards needed for a sustainable nuclear industry. The values and ethics of individuals and organizational units play an equally important role. This publication is addressed primarily to senior managers of operating organizations, as experience has shown that, in order to succeed, such initiatives need to come from and be continually supported by the highest levels of the organization. This publication was developed under an IAEA project in its 2006-7 programme entitled Achieving Excellence in the Performance of Nuclear Power Plant Personnel. The principal objectives of this project were: - To enhance the capability of Member States to utilize proven practices accumulated, developed and transferred by the Agency for improving personnel performance and maintaining high standards, and - To demonstrate how positive attitudes and professionalism, appropriate performance management, adherence to a systematic approach to training, quality management and the use of effective information and knowledge management technologies contribute to the success in achieving organization objectives in a challenging business environment

  17. Modernizing and Maintaining Instrumentation and Control Systems in Nuclear Power Plants

    International Nuclear Information System (INIS)

    Naser, Joseph; Torok, Raymond; Shankar, Ramesh

    2003-01-01

    Deregulation of the electric utilities has made a major impact on nuclear power plants. To be competitive, more emphasis is being put on cost-effective production of electricity with a more critical look at whether a system should be modernized due to obsolescence, reliability, or productivity concerns. Instrumentation and control (I and C) systems play an important role in reducing the cost of producing electricity while maintaining or enhancing safety. Systems that are well designed, reliable, enhance productivity, and are cost-effective to operate and maintain can reduce the overall costs. Modern technology with its ability to better provide and use real-time information offers an effective platform for modernizing systems. At the same time, new technology brings new challenges and issues, especially for safety systems in nuclear power plants. To increase competitiveness, it is important to take advantage of the opportunities offered by modern technology and to address the new challenges and issues in a cost-effective manner. The Electric Power Research Institute (EPRI) and its member utilities have been working together with other members of the nuclear industry since 1990 to address I and C modernization and maintenance issues. The EPRI I and C Program has developed a life-cycle management approach for I and C systems that involves the optimization of maintenance, monitoring, and capital resources to sustain safety and performance throughout the plant life. Strategic planning methodologies and implementation guidelines addressing digital I and C issues in nuclear power plants have been developed. Work is ongoing in diverse areas to support the design, implementation, and operation of new digital systems. Technology transfer is an integral part of this I and C program

  18. Design of an organic simplified nuclear reactor

    Energy Technology Data Exchange (ETDEWEB)

    Shirvan, Koroush [Dept. of Nuclear Science and Engineering, Massachusetts Institute of Technology, Cambridge (United States); Forrest, Eric [Primary Standards Laboratory, Sandia National Laboratories, Albuquerque (United States)

    2016-08-15

    Numerous advanced reactor concepts have been proposed to replace light water reactors ever since their establishment as the dominant technology for nuclear energy production. While most designs seek to improve cost competitiveness and safety, the implausibility of doing so with affordable materials or existing nuclear fuel infrastructure reduces the possibility of near-term deployment, especially in developing countries. The organic nuclear concept, first explored in the 1950s, offers an attractive alternative to advanced reactor designs being considered. The advent of high temperature fluids, along with advances in hydrocracking and reforming technologies driven by the oil and gas industries, make the organic concept even more viable today. We present a simple, cost-effective, and safe small modular nuclear reactor for offshore underwater deployment. The core is moderated by graphite, zirconium hydride, and organic fluid while cooled by the organic fluid. The organic coolant enables operation near atmospheric pressure and use of plain carbon steel for the reactor tank and primary coolant piping system. The core is designed to mitigate the coolant degradation seen in early organic reactors. Overall, the design provides a power density of 40 kW/L, while reducing the reactor hull size by 40% compared with a pressurized water reactor while significantly reducing capital plant costs.

  19. Design of an Organic Simplified Nuclear Reactor

    Directory of Open Access Journals (Sweden)

    Koroush Shirvan

    2016-08-01

    Full Text Available Numerous advanced reactor concepts have been proposed to replace light water reactors ever since their establishment as the dominant technology for nuclear energy production. While most designs seek to improve cost competitiveness and safety, the implausibility of doing so with affordable materials or existing nuclear fuel infrastructure reduces the possibility of near-term deployment, especially in developing countries. The organic nuclear concept, first explored in the 1950s, offers an attractive alternative to advanced reactor designs being considered. The advent of high temperature fluids, along with advances in hydrocracking and reforming technologies driven by the oil and gas industries, make the organic concept even more viable today. We present a simple, cost-effective, and safe small modular nuclear reactor for offshore underwater deployment. The core is moderated by graphite, zirconium hydride, and organic fluid while cooled by the organic fluid. The organic coolant enables operation near atmospheric pressure and use of plain carbon steel for the reactor tank and primary coolant piping system. The core is designed to mitigate the coolant degradation seen in early organic reactors. Overall, the design provides a power density of 40 kW/L, while reducing the reactor hull size by 40% compared with a pressurized water reactor while significantly reducing capital plant costs.

  20. Knowledge management for nuclear industry operating organizations

    International Nuclear Information System (INIS)

    2006-10-01

    research facilities to reduce operating costs and a decline in support to the universities to reduce overheads. The above factors have led to a reduction in technical innovation and a potential loss of technical competences that have drawn the attention of many concerned parties to the need for effective strategies and policies for nuclear knowledge management. The Director General of the IAEA, Mohamed ElBaradei, in his statement to the forty-seventh regular session of the IAEA General Conference 2003, said: 'Whether or not nuclear power witnesses an expansion in the coming decades, it is essential that we preserve nuclear scientific and technical competence for the safe operation of existing facilities and applications. Effective management of nuclear knowledge should include succession planning for the nuclear work force, the maintenance of the 'nuclear safety case' for operational reactors, and retention of the nuclear knowledge accumulated over the past six decades'. This report is intended for senior and middle level managers of nuclear industry operating organizations and provides practical information that can be used to improve knowledge management (KM) in such organizations. The information provided in this report is based upon actual experiences of Member State operating organizations as well as other related industries. The Nuclear Power Industry's Ageing Workforce: Transfer of Knowledge to the Next Generation, IAEA-TECDOC-1399, highlighted some of the knowledge management issues in Member States resulting from the large number of retiring NPP personnel who had been involved with the commissioning and initial operation of NPPs. This report complements that publication by broadening the scope of KM strategic issues, methods and techniques for nuclear industry operating organizations

  1. Organic diagenesis in commercial nuclear wastes

    International Nuclear Information System (INIS)

    Toste, A.P.; Lechner-Fish, T.J.

    1988-01-01

    The nuclear industry currently faces numerous challenges. Large volumes of already existing wastes must be permanently disposed using environmentally acceptable technologies. Numerous criteria must be addressed before wastes can be permanently disposed. Waste characterization is certainly one of the key criteria for proper waste management. some wastes are complex melting pots of inorganics, radiochemicals, and, occasionally, organics. It is clear, for example, that organics have been used extensively in nuclear operations, such as waste reprocessing, and continue to be used widely as solvents, decontamination agents, etc. The authors have analyzed the organic content of many kinds of nuclear wastes, ranging from commercial to defense wastes. In this paper, the finale analyses are described of three commercial wastes: one waste from a pressurized water reactor (PWR) and two wastes from a boiling water reactor (BWR). The PWR waste is a boric acid concentrate waste. The two BWR wastes, BWR wastes Nos. 1 and 2, are evaporator concentrates of liquid wastes produced during the regeneration of ion-exchange resins used to purify reactor process water. In preliminary analyses, which were reported previously, a few know organics and myriad unknowns were detected. Recent reexamination of mass-spectral data, coupled with reanalysis of the wastes, has resulted in the firm identification of the unknowns. Most of the compounds, over thirty distinct organics, are derived from the degradation, or diagenesis, of source-term organics, revealing, for the first time, that organic diagenesis in commercial wastes is both vigorous and varied

  2. Managing organizational change in nuclear organizations

    International Nuclear Information System (INIS)

    2014-01-01

    It is widely recognized that engineering changes, if not properly considered and controlled, can have potentially major safety implications; however, organizational changes can also have potentially major safety implications. This publication is intended to assist the management of nuclear organizations in identifying, planning and implementing organizational change. The driving force for the change may be internal or external. Based on the assumption that any change made within a facility applying nuclear technology has the potential to impact safety and effectiveness, the publication provides a description of the basic principles for managing and implementing the organizational change effectively while remaining focused on safe and reliable operation. The guidance contained in the publication is relevant to all organizational changes within nuclear organizations

  3. Large research infrastrucures and networking. Two key factors for maintaining nuclear expertise in Europe

    International Nuclear Information System (INIS)

    Cognet, G.; Iracane, D.

    2004-01-01

    Large research infrastructures are of key importance to improve the efficiency and the safety of nuclear energy production. To support present and coming power reactors and fuel cycle facilities and to develop future systems, it is necessary to optimise these infrastructures and their use by taking into account the networking of existing facilities, the access by the European researchers to conduct their own research projects and the creation of new installations when facing ageing issues. Large infrastructures include material testing reactor, hot laboratories for material and fuel under irradiation studies, fuel cycle researches and facilities dedicated to severe accident studies. For example, the CEA severe accident study platform has been recently used by a Bulgarian team to conduct its own research project with a grant provided by the European Commission. Furthermore, because present European material testing reactors are ageing, renewing the irradiation capability is an important and structuring stake for the fission research in Europe in order to continue safe and optimised operations of existing reactors, to support Generation 4 RTD and to keep alive competences. Considering that, CEA has decided to launch the project Jules Horowitz aiming at building a new research reactor. The access to the CEA facilities, including the Jules Horowitz reactor, combined with equivalent possibilities of access to other European facilities through a specific platform would help to develop a long-term vision, to create a coherent and dynamic strategy, to contribute to the stimulation of a large cooperation on nuclear fission, to enable a common approach of safety issues, to gather competencies, to promote the attractiveness of nuclear research to young scientists and to maintain European nuclear expertise at the highest level. This paper intends to provide a view of the existing and needed infrastructures, discuss the ways of access and finally open the discussion on the

  4. Designing the owner's nuclear project management organization

    International Nuclear Information System (INIS)

    Cooke, T.C.; Peck, B.H.

    1976-01-01

    Few decisions are more important to an electric utility company than the one to build a nuclear generating facility. This decision will require continuous management attention to the nuclear project for periods of up to ten years on the part of the utility. Effective management of such a large, complex project requires an owner's organization skilled in such areas as engineering, heavy construction, procurement, and project control. The paper describes a method for designing the owner's nuclear organization. Factors considered include the identification of milestone events and phases of the project and identification of key organizational groups and their degree of involvement. A series of important decision milestones is also identified for structuring the organization. A step-by-step analysis involving a set of evaluation criteria results in a recommended organization that can be staffed by the owner according to the degree of involvement desired. This technique of analysis could also be performed using different evaluation criteria resulting in other options for the owner's organization

  5. The effect of organic diets on the performance of pullets maintained under semi-organic conditions.

    Science.gov (United States)

    Acamovic, T; Sandilands, V; Kyriazakis, I; Sparks, N

    2008-01-01

    The effects of organic diets, with or without supplements of betaine, saponin, fructo-oligosaccharide and methionine, on the health, performance and gut flora of pullets were investigated. A comparison was also made between birds fed organic diets and those fed a non-organic diet. Day-old Lohmann Tradition pullets were reared in 24 groups of 64 chicks indoors until 11 weeks, and then in 48 groups of 24 to 27 chicks with access to range until 17 weeks of age. Groups of birds were fed one of eight diets, a conventional rearing diet with supplementary amino acids, an organic basal diet, organic basal plus methionine and organic basal supplemented with one of the test ingredients. At most stages of growth the birds fed the conventional diet and those fed the basal diet with methionine performed better than those that had no supplemental methionine. Other dietary treatments had no consistently significant effect on growth, the microbial populations within the gastro-intestinal tract of the birds or the number of parasite eggs excreted. After 5 weeks with access to range, the birds that were fed three out of five diets regarded as deficient in sulphur amino acids achieved similar weights (P > 0.05) to birds that received diets adequate in sulphur amino acids. Health and welfare of birds fed organic diets was not adversely affected; however, an investigation of birds housed in larger flocks and taken into the laying phase, when physical demands on birds are greatest, is required.

  6. Nucleolus association of chromosomal domains is largely maintained in cellular senescence despite massive nuclear reorganisation.

    Directory of Open Access Journals (Sweden)

    Stefan Dillinger

    Full Text Available Mammalian chromosomes are organized in structural and functional domains of 0.1-10 Mb, which are characterized by high self-association frequencies in the nuclear space and different contact probabilities with nuclear sub-compartments. They exhibit distinct chromatin modification patterns, gene expression levels and replication timing. Recently, nucleolus-associated chromosomal domains (NADs have been discovered, yet their precise genomic organization and dynamics are still largely unknown. Here, we use nucleolus genomics and single-cell experiments to address these questions in human embryonic fibroblasts during replicative senescence. Genome-wide mapping reveals 1,646 NADs in proliferating cells, which cover about 38% of the annotated human genome. They are mainly heterochromatic and correlate with late replicating loci. Using Hi-C data analysis, we show that interactions of NADs dominate interphase chromosome contacts in the 10-50 Mb distance range. Interestingly, only minute changes in nucleolar association are observed upon senescence. These spatial rearrangements in subdomains smaller than 100 kb are accompanied with local transcriptional changes. In contrast, large centromeric and pericentromeric satellite repeat clusters extensively dissociate from nucleoli in senescent cells. Accordingly, H3K9me3-marked heterochromatin gets remodelled at the perinucleolar space as revealed by immunofluorescence analyses. Collectively, this study identifies connections between the nucleolus, 3D genome structure, and cellular aging at the level of interphase chromosome organization.

  7. Nuclear reactor control method for maintaining an appreciably constant axial distribution of power with load variations

    International Nuclear Information System (INIS)

    Morita, Toshio.

    1975-01-01

    A nuclear reactor control method is described in which the power variations of the reactor are controlled partly by varying the concentration of the neutron absorbing element and partly by varying the positions of the control rods, in order to maintain the axial distribution of power appreciably symmetrical during the normal operation of the reactor. The control points are located in the upper and lower halves of the core. The controls are operated to maintain the output power difference between the upper and lower halves of the core, based on the total output power (axial deviation) significantly equal to a predetermined optimum figure during the entire running of the reactor, including when there are power variations. The optimum value is obtained by determining the axial deviation at full power with the xenon in balance and all the control rods withdrawn from the fuel area of the core. This optimum value is recalculated after a period appreciably equal to that of a month's operation at full power. This method applies in particular to PWR type reactors [fr

  8. The year 2000 embedded systems problem to maintain the safety of nuclear installations

    International Nuclear Information System (INIS)

    Ardisasmita, M.S.

    1999-01-01

    The Y2K problem may impact on nuclear installations in a number of ways because embedded systems are used in nuclear routine operation, monitoring and control system. The very simplest embedded systems are capable of performing only a single function or set of functions to meet a single predetermined purpose. In more complex systems the functioning of the embedded system is determined by an application program that enables the embedded system to be used for a particular purpose in a specific application. The simplest devices consist of a single microprocessor which may itself be packaged with other chips in a hybrid system or Application Specific Integrated Circuit (ASIC). Its input comes from a detector or sensor and its output goes to a switch or activator which may start or stop the operation of a positioning motors or, by operating a valve, may control the flow of cooling system to reactor core. Embedded systems in our organization are also be found in Batan security systems. These include systems for the security of buildings and premises, and in the communication systems on which these depend. In the enclosed paper we demonstrate the use of analytic model and reliability analysis. The subject of this reliability test is to detect the components of the embedded system with PLC's that could fail on Y2K problem in nuclear installation and safety system. (author)

  9. Academic portfolio in the digital era: organizing and maintaining a portfolio using reference managers.

    Science.gov (United States)

    Bhargava, Puneet; Patel, Vatsal B; Iyer, Ramesh S; Moshiri, Mariam; Robinson, Tracy J; Lall, Chandana; Heller, Matthew T

    2015-02-01

    The academic portfolio has become an integral part of the promotions process. Creating and maintaining an academic portfolio in paper-based or web-based formats can be a cumbersome and time-consuming task. In this article, we describe an alternative way to efficiently organize an academic portfolio using a reference manager software, and discuss some of the afforded advantages. The reference manager software Papers (Mekentosj, Amsterdam, The Netherlands) was used to create an academic portfolio. The article outlines the key steps in creating and maintaining a digital academic portfolio. Using reference manager software (Papers), we created an academic portfolio that allows the user to digitally organize clinical, teaching, and research accomplishments in an indexed library enabling efficient updating, rapid retrieval, and easy sharing. To our knowledge, this is the first digital portfolio of its kind.

  10. Integrated equipment for increasing and maintaining coolant pressure in primary circuit of PWR nuclear power plant

    International Nuclear Information System (INIS)

    Sykora, D.

    1986-01-01

    An open heat pump circuit is claimed connected to the primary circuit. The pump circuit consists of a steam pressurizer with a built-in steam distributor, a compressor, an expander, a reducing valve, an auxiliary pump, and of water and steam pipes. The operation is described and a block diagram is shown of integrated equipment for increasing and maintaining pressure in the nuclear power plant primary circuit. The appropriate entropy diagram is also shown. The advantage of the open pump circuit consists in reducing the electric power input and electric power consumption for the steam pressurizers, removing entropy loss in heat transfer with high temperature gradient, in the possibility of inserting, between the expander and the auxiliary pump, a primary circuit coolant treatment station, in simplified design and manufacture of the high-pressure steam pressurizer vessel, reducing the weight of the steam pressurizer by changing its shape from cylindrical to spherical, increasing the rate of pressure growth in the primary circuit. (E.S.)

  11. Maintaining the system with tokenism: bolstering individual mobility beliefs and identification with a discriminatory organization.

    Science.gov (United States)

    Danaher, Kelly; Branscombe, Nyla R

    2010-06-01

    Two experiments examined the effects of gender-based token hiring practices in organizational settings. In Expt 1, women were exposed to organizational hiring practices that were open, token, or closed. Token practices served to perpetuate inequality by maintaining individual mobility beliefs and organizational identification. In Expt 2, both men and women imagined working for a corporation that planned to implement open, token, or closed hiring practices. Although women reported experiencing negative emotions in the closed and token conditions compared to the open condition, token practices maintained positive perceptions of the organization and individual mobility beliefs compared to the closed condition. Men endorsed more individual mobility beliefs as well as positive emotions in the token and closed conditions compared to the open condition. Token practices distort perceptions of fairness in both women and men. For women, token practices make group boundaries seem more negotiable than they actually are, while for men token practices legitimize their group's dominance.

  12. Should Organic Agriculture Maintain Its Opposition to GM? New Techniques Writing the Same Old Story

    Directory of Open Access Journals (Sweden)

    Fern Wickson

    2016-10-01

    Full Text Available Biotechnology is diversifying rapidly through the development and application of new approaches to genome editing and ongoing research into synthetic biology. Proponents of biotechnology are enthusiastic about these new developments and have recently begun calling for environmental movements to abandon their campaigns against Genetically Modified Organisms (GMOs and for organic agriculture to reconsider its exclusion of Genetic Modification (GM. In this article, we begin by describing the diversity of practices that cluster under both the terms GM and organic and show that although there is a clash of different cultures of agriculture at stake, there is also a spectrum of practices existing between these two poles. Having established the terms of the debate, we then go on to analyse whether the organic movement should reconsider its position on GM in light of new plant breeding techniques (NPBTs, using the criteria highlighted as important by the International Federation of Organic Agriculture Movements (IFOAM in their 2016 draft revised position on GMOs. Through this analysis, we suggest that given the in-context-trajectory of biotechnology development, the continued narrow framing of agricultural problems and the ongoing exclusion of important socio-economic, political and cultural dimensions, the organic movement is justified in maintaining its opposition to GM in the face of NPBTs.

  13. The IAEA, nuclear power and sustainable development. Maintaining and increasing the overall assets available to future generations

    International Nuclear Information System (INIS)

    2001-01-01

    In the framework of one of the fundamental objectives of the IAEA mandate to enhance the contribution of nuclear technologies towards meeting the needs of Member States, the present status, all the aspects, and the future of nuclear power are reviewed. The development of nuclear power broadens the natural resource base usable for energy production, increases human and man-made capital, and when safely handled has little impact on ecosystems. This means that it could meet the central goal of sustainable development, considering that it covers maintaining or increasing the overall assets available to future generations, while minimizing consumption of finite resources and not exceeding the carrying capacities of ecosystems

  14. Educational Approach to Maintain a Suitable Knowledge and Expertise in Nuclear Field: Case of Morocco

    International Nuclear Information System (INIS)

    Choukri, A.; Hakam, O.K.

    2016-01-01

    Full text: Nuclear knowledge management has become an increasingly important element of the nuclear sector in recent years, resulting from a number of challenges and trends. The development of any national nuclear energy programme is dependent on the successful development of the workforce, through a sustainable nuclear educational and training programme supported by government and industry. Morocco has continuously provided educational programmes in nuclear field at its universities since 1967. These academic programmes focused on nuclear sciences, nuclear engineering, radiation protection, etc., and were intended to undergraduate and postgraduate students. Nuclear techniques have known also an increased contribution to medicine, agriculture, industry and research in Morocco. Some educational and training programmes have been elaborated to develop human resources needed in different domains. University of Ibn Tofail, has launched, since september 2010, a national master’s programme in the field of nuclear sciences which aims to provide knowledge directly used in the various sectors using nuclear techniques and requiring radiation protection, nuclear safety and security including notions on nuclear knowledge management. For an effective management of nuclear knowledge, the educational didactic has been improved increasingly. Some new techniques, materiel and styles have been employed such as demonstrations, group exercises, e-learning, visio-conferences. (author

  15. Maintaining nutritional adequacy during a prolonged food crisis. [Basic foods for post-nuclear attack use

    Energy Technology Data Exchange (ETDEWEB)

    Franz, K.B.; Kearny, C.H.

    1979-08-01

    This handbook is the first to assemble nutritional information and make recommendations on the efficient use of unprocessed grains, beans, and other elemental foods during the aftermath of a nuclear war. These basic foods would constitute the main resources to combat famine after a major nuclear attack. Such an attack would reduce and probably eliminate most commercial food processing for many months. To decision makers, this handbook should prove useful on basic aspects of nutrition in a long-term survival situation. These decision makers might range from the heads of families to government officials. Recommendations for nutrition given by organizations experienced in crisis feeding are reviewed and compared. Based on the best nutritional information available, emergency dietary recommendations are made for minimum and intermediate goals. The emergency dietary recommendations are applied to food for practical survival rations. Long-term survival rations for Americans are evaluated. These rations are (1) ten single-food rations; (2) four cereal-legume rations, ratio 4:1; (3) four cereal-legume rations, ratio 8:1; and (4) four cereal-legume-dry milk rations. The 22 different survival rations are detailed and summarized in 20 tables which list their nutritional adequacies and deficiences. Expedient procedures are given by which basic foods may be processed and cooked to provide a more healthful diet than most Americans believe possible. Special attention is given to the requirements of infants, children, and pregnant or lactating women. The eleven appendixes provide a wealth of specialized information. Among these appendixes is one that summarizes new and improved expedient methods for removing radioactive fallout and other contaminants from water. Another appendix is a comprehensive account of ways to sprout seeds to produce vitamins and improve palatability. (ERB)

  16. Measures geared to maintain the competence of operating personnel at Grohnde nuclear power plant

    International Nuclear Information System (INIS)

    Bohr, H.

    1986-01-01

    Organizational structure of the German power plant 'Gemeinschaftskernkraftwerk Grohnde GmbH'. The plant characteristics of the tasks and duties and definition of competence. Measures to maintain competence. The experience by the realization of training programs to maintain competence. (orig.)

  17. MAINTAINING THE VIABILITY ANIMALS AND PLANT ORGANISMS IN URBAN ECOSISTEMS (ECOLOGO-GENETIC APPROUCH

    Directory of Open Access Journals (Sweden)

    V. M. Makeev

    2014-01-01

    Full Text Available Ecologo- genetic approach is the basis genourbanology - independent scientific perspective and practical direction of the selected authors (the synthesis of population genetics and ecology of the system, which is committed to the knowledge of the genetic parameters and laws of conservation of human and ecosystem stability especially in urban landscapes. This approach (that is methodology, the concept, strategy, technologies has been tested in the ecosystems of the urban specially protected territories of Moscow and Moscow region. The state of the genofond of the organisms (model species populations whose natural habitat is the fragmented landscape of Moscow and the Moscow Region (36 animals populations and 4 plants populations was assessed. Our experience confirms efficiency of this approach in maintaining the viability animals and plant organisms in urban ecosystems.

  18. DNA Methylation, Nuclear Organization, and Cancer.

    Science.gov (United States)

    Madakashira, Bhavani P; Sadler, Kirsten C

    2017-01-01

    The dramatic re-organization of the cancer cell nucleus creates telltale morphological features critical for pathological staging of tumors. In addition, the changes to the mutational and epigenetic landscape in cancer cells alter the structure and stability of the genome and directly contribute to malignancy. DNA methylation is one of the best studied epigenetic changes in cancer, as nearly every type of cancer studied shows a loss of DNA methylation spread across most of the genome. This global hypomethylation is accompanied by hypermethylation at distinct loci, and much of the work on DNA methylation in cancer has focused on how local changes contribute to gene expression. However, the emerging picture is that the changes to DNA methylation in cancer cells has little direct effect on gene expression but instead impacts the organization of the genome in the nucleus. Several recent studies that take a broad view of the cancer epigenome find that the most profound changes to the cancer methylome are spread across large segments of the genome, and that the focal changes are reflective of a whole reorganization of epigenome. Hallmarks of nuclear reorganization in cancer are found in the long regions of chromatin marked by histone methylation (LOCKs) and nuclear lamina interactions (LADs). In this review, we focus on a novel perspective that DNA methylation changes in cancer impact the global structure of heterochromatin, LADs and LOCKs, and how these global changes, in turn, contribute to gene expression changes and genomic stability.

  19. DNA Methylation, Nuclear Organization, and Cancer

    Directory of Open Access Journals (Sweden)

    Bhavani P. Madakashira

    2017-06-01

    Full Text Available The dramatic re-organization of the cancer cell nucleus creates telltale morphological features critical for pathological staging of tumors. In addition, the changes to the mutational and epigenetic landscape in cancer cells alter the structure and stability of the genome and directly contribute to malignancy. DNA methylation is one of the best studied epigenetic changes in cancer, as nearly every type of cancer studied shows a loss of DNA methylation spread across most of the genome. This global hypomethylation is accompanied by hypermethylation at distinct loci, and much of the work on DNA methylation in cancer has focused on how local changes contribute to gene expression. However, the emerging picture is that the changes to DNA methylation in cancer cells has little direct effect on gene expression but instead impacts the organization of the genome in the nucleus. Several recent studies that take a broad view of the cancer epigenome find that the most profound changes to the cancer methylome are spread across large segments of the genome, and that the focal changes are reflective of a whole reorganization of epigenome. Hallmarks of nuclear reorganization in cancer are found in the long regions of chromatin marked by histone methylation (LOCKs and nuclear lamina interactions (LADs. In this review, we focus on a novel perspective that DNA methylation changes in cancer impact the global structure of heterochromatin, LADs and LOCKs, and how these global changes, in turn, contribute to gene expression changes and genomic stability.

  20. The Role of Performance Management in Creating and Maintaining a High-Performance Organization

    Directory of Open Access Journals (Sweden)

    André A. de Waal

    2015-04-01

    Full Text Available There is still a good deal of confusion in the literature about how the use of a performance management system affects overall organizational performance. Some researchers find that performance management enhances both the financial and non-financial results of an organization, while others do not find any positive effects or, at most, ambiguous effects. An important step toward getting more clarity in this relationship is to investigate the role performance management plays in creating and maintaining a high-performance organization (HPO. The purpose of this study is to integrate performance management analysis (PMA and high-performance organization (HPO. A questionnaire combining questions on PMA dimensions and HPO factors was administered to two European-based multinational firms. Based on 468 valid questionnaires, a correlation analysis was performed on the PMA dimensions and the HPO factors in order to test the impact of performance management on the factors of high organizational performance. The results show strong and significant correlations between all the PMA dimensions and all the HPO factors, indicating that a performance management system that fosters performance-driven behavior in the organization is of critical importance to strengthen overall financial and non-financial performance.

  1. What Pacemakers Can Teach Us about the Ethics of Maintaining Artificial Organs.

    Science.gov (United States)

    Hutchison, Katrina; Sparrow, Robert

    2016-11-01

    One day soon it may be possible to replace a failing heart, liver, or kidney with a long-lasting mechanical replacement or perhaps even with a 3-D printed version based on the patient's own tissue. Such artificial organs could make transplant waiting lists and immunosuppression a thing of the past. Supposing that this happens, what will the ongoing care of people with these implants involve? In particular, how will the need to maintain the functioning of artificial organs over an extended period affect patients and their doctors and the responsibilities of those who manufacture such devices? Drawing on lessons from the history of the cardiac pacemaker, this article offers an initial survey of the ethical issues posed by the need to maintain and service artificial organs. We briefly outline the nature and history of cardiac pacemakers, with a particular focus on the need for technical support, maintenance, and replacement of these devices. Drawing on the existing medical literature and on our conversations and correspondence with cardiologists, regulators, and manufacturers, we describe five sources of ethical issues associated with pacemaker maintenance: the location of the devices inside the human body, such that maintenance generates surgical risks; the complexity of the devices, which increases the risk of harms to patients as well as introducing potential injustices in access to treatment; the role of software-particularly software that can be remotely accessed-in the functioning of the devices, which generates privacy and security issues; the impact of continual development and improvement of the device; and the influence of commercial interests in the context of a medical device market in which there are several competing products. Finally, we offer some initial suggestions as to how these questions should be answered. © 2016 The Hastings Center.

  2. Quantum self-organization and nuclear collectivities

    Science.gov (United States)

    Otsuka, T.; Tsunoda, Y.; Togashi, T.; Shimizu, N.; Abe, T.

    2018-02-01

    The quantum self-organization is introduced as one of the major underlying mechanisms of the quantum many-body systems. In the case of atomic nuclei as an example, two types of the motion of nucleons, single-particle states and collective modes, dominate the structure of the nucleus. The outcome of the collective mode is determined basically by the balance between the effect of the mode-driving force (e.g., quadrupole force for the ellipsoidal deformation) and the resistance power against it. The single-particle energies are one of the sources to produce such resistance power: a coherent collective motion is more hindered by larger gaps between relevant single particle states. Thus, the single-particle state and the collective mode are “enemies” each other. However, the nuclear forces are demonstrated to be rich enough so as to enhance relevant collective mode by reducing the resistance power by changing singleparticle energies for each eigenstate through monopole interactions. This will be verified with the concrete example taken from Zr isotopes. Thus, when the quantum self-organization occurs, single-particle energies can be self-organized, being enhanced by (i) two quantum liquids, e.g., protons and neutrons, (ii) two major force components, e.g., quadrupole interaction (to drive collective mode) and monopole interaction (to control resistance). In other words, atomic nuclei are not necessarily like simple rigid vases containing almost free nucleons, in contrast to the naïve Fermi liquid picture. Type II shell evolution is considered to be a simple visible case involving excitations across a (sub)magic gap. The quantum self-organization becomes more important in heavier nuclei where the number of active orbits and the number of active nucleons are larger. The quantum self-organization is a general phenomenon, and is expected to be found in other quantum systems.

  3. Polymer physics of nuclear organization and function

    Energy Technology Data Exchange (ETDEWEB)

    Amitai, A. [Department of Chemical Engineering, Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Holcman, D., E-mail: david.holcman@ens.fr [Department of Applied Mathematics and Theoretical Physics (DAMTP), University of Cambridge, Churchill College, CB30DS, Cambridge (United Kingdom); Ecole Normale Superieure, Paris (France)

    2017-03-23

    We review here recent progress to link the nuclear organization to its function, based on elementary physical processes such as diffusion, polymer dynamics of DNA, chromatin and the search mechanism for a small target by double-stranded DNA (dsDNA) break. These physical models and their analysis make it possible to compute critical rates involved in cell reorganization timing, which depend on many parameters. In the framework of polymer models, various empirical observations are interpreted as anomalous diffusion of chromatin at various time scales. The reviewed theoretical approaches offer a framework for extracting features, biophysical parameters, predictions, and so on, based on a large variety of experimental data, such as chromosomal capture data, single particle trajectories, and more. Combining theoretical approaches with live cell microscopy data should unveil some of the still unexplained behavior of the nucleus in carrying out some of its key function involved in survival, DNA repair or gene activation.

  4. Critical carbon input to maintain current soil organic carbon stocks in global wheat systems.

    Science.gov (United States)

    Wang, Guocheng; Luo, Zhongkui; Han, Pengfei; Chen, Huansheng; Xu, Jingjing

    2016-01-13

    Soil organic carbon (SOC) dynamics in croplands is a crucial component of global carbon (C) cycle. Depending on local environmental conditions and management practices, typical C input is generally required to reduce or reverse C loss in agricultural soils. No studies have quantified the critical C input for maintaining SOC at global scale with high resolution. Such information will provide a baseline map for assessing soil C dynamics under potential changes in management practices and climate, and thus enable development of management strategies to reduce C footprint from farm to regional scales. We used the soil C model RothC to simulate the critical C input rates needed to maintain existing soil C level at 0.1° × 0.1° resolution in global wheat systems. On average, the critical C input was estimated to be 2.0 Mg C ha(-1) yr(-1), with large spatial variability depending on local soil and climatic conditions. Higher C inputs are required in wheat system of central United States and western Europe, mainly due to the higher current soil C stocks present in these regions. The critical C input could be effectively estimated using a summary model driven by current SOC level, mean annual temperature, precipitation, and soil clay content.

  5. Modernisation for maintaining and improving safety at Nordic nuclear power plants

    International Nuclear Information System (INIS)

    Hammer, L.; Wahlstroem, B.; Simola, K.

    1998-02-01

    The safety practices in Finland and Sweden are described and compared in regard of effecting modernisation for safety of the nuclear plants in the two countries, considering new technology and advancing safety requirements as proposed for new reactors. Particular attention is given to strategies for applying new safety requirements to reactors built to earlier standards, and to the interplay between the nuclear utilities and the safety authorities. Overviews are given of past and current modernisation of the nuclear power plants in Finland and Sweden. The management procedures in controlling the implementation of modifications to the nuclear power plants are described and discussed in regard of prevailing differences between Finnish and Swedish practices. A formal modelling technique (SADT) was applied for capture of the essential contents of the relevant documented procedures. Two examples of recent plant modifications in the Finnish nuclear plants in Olkiluoto and Loviisa are described and discussed in greater detail. Recommendations are given. (au)

  6. AECL's reliability and maintainability program

    International Nuclear Information System (INIS)

    Wolfe, W.A.; Nieuwhof, G.W.E.

    1976-05-01

    AECL's reliability and maintainability program for nuclear generating stations is described. How the various resources of the company are organized to design and construct stations that operate reliably and safely is shown. Reliability and maintainability includes not only special mathematically oriented techniques, but also the technical skills and organizational abilities of the company. (author)

  7. Nuclear Criticality Safety Organization guidance for the development of continuing technical training. Revision 1

    International Nuclear Information System (INIS)

    Carroll, K.J.; Taylor, R.G.; Worley, C.A.

    1997-01-01

    The Nuclear Criticality Safety Organization (NCSO) is committed to developing and maintaining a staff of highly qualified personnel to meet the current and anticipated needs in nuclear criticality safety at the Oak Ridge Y-12 Plant and throughout the DOE complex. Continuing technical training is training outside of the initial qualification program to address identified organization-wide needs. Typically, this training is used to improve organization performance in the conduct of business. This document provides guidelines for the development of the technical portions of the Continuing Training Program. It is not a step-by-step procedure, but a collection of considerations to be used during the development process

  8. Knowledge Management for Nuclear Research and Development Organizations (Russian Edition)

    International Nuclear Information System (INIS)

    2016-01-01

    This publication elaborates on the role of nuclear knowledge management in a research and development (R&D) context, and on the importance of facilitating innovation and future development of nuclear technologies for nuclear power, its associated fuel cycles, and nuclear applications in medicine, industry and agriculture. It highlights aspects such as transferring and preserving knowledge, exchanging information, establishing and supporting cooperative networks, and training the next generation of nuclear experts. It concludes with basic concepts, trends and key drivers for nuclear knowledge management for R&D project managers and other workers from nuclear R&D organizations.

  9. Knowledge Management for Nuclear Research and Development Organizations

    International Nuclear Information System (INIS)

    2012-05-01

    This publication elaborates on the role of nuclear knowledge management in a research and development (R and D) context, and on the importance of facilitating innovation and future development of nuclear technologies for nuclear power, its associated fuel cycles and nuclear applications in medicine, industry and agriculture. It highlights aspects including transferring and preserving knowledge, exchanging information, establishing and supporting cooperative networks, and training the next generation of nuclear experts. It concludes with basic concepts, trends and key drivers for nuclear knowledge management to R and D project managers and other workers from nuclear R and D organizations.

  10. Organization and safety in nuclear power plants

    International Nuclear Information System (INIS)

    Marcus, A.A.; Nichols, M.L.; Bromiley, P.; Olson, J.; Osborn, R.N.; Scott, W.; Pelto, P.; Thurber, J.

    1990-05-01

    Perspectives from industry, academe, and the NRC are brought together in this report and used to develop a logical framework that links management and organization factors and safety in nuclear power plant performance. The framework focuses on intermediate outcomes which can be predicted by organizational and management factors, and which are subsequently linked to safety. The intermediate outcomes are efficiency, compliance, quality, and innovation. The organization and management factors can be classified in terms of environment, context, organizational governance, organizational design, and emergent processes. Initial empirical analyses were conducted on a limited set of hypotheses derived from the framework. One set of hypotheses concerned the relationships between one of the intermediate outcome variables, efficiency, as measured by critical hours and outage rate, and safety, as measured by 5 NRC indicators. Results of the analysis suggest that critical hours and outage rates and safety, as measured in this study, are not related to each other. Hypotheses were tested concerning the effects on safety and efficiency of utility financial resources and the lagged recognition and correction of problems that accompanies the reporting of major violations and licensee event reports. The analytical technique employed was regression using polynomial distributed lags. Results suggest that both financial resources and organizational problem solving/learning have significant effects on the outcome variables when time is properly taken into account. Conclusions are drawn which point to this being a promising direction to proceed, though with some care, due to the current limitations of the study. 138 refs., 36 figs., 9 tabs

  11. Phosphorylation of DEPDC1 at Ser110 is required to maintain centrosome organization during mitosis.

    Science.gov (United States)

    Chen, Dan; Ito, Satoko; Hyodo, Toshinori; Asano-Inami, Eri; Yuan, Hong; Senga, Takeshi

    2017-09-15

    DEPDC1 (DEP domain containing 1) is overexpressed in multiple cancers and is associated with cell cycle progression. In this report, we have investigated the expression, localization, phosphorylation and function of DEPDC1 during mitosis. DEPDC1 has two isoforms (isoform a and isoform b), and both of them are increased in mitosis and degraded once cells exit mitosis. DEPDC1a is localized to the centrosome in metaphase, whereas DEPDC1b is localized to the entire cell cortex during mitosis. DEPDC1a, but not DEPDC1b, was required for the integrity of centrosome and organization of the bipolar spindle. Mass spectrometry and biochemical analyses revealed phosphorylation of DEPDC1 at Ser110. The phosphorylation of Ser110 is essential for localization of DEPDC1a to the centrosome. Consistently, non-phosphorylation mutants of DEPDC1a did not rescue disruption of centrosome organization by depletion of endogenous DEPDC1. Our results show a novel role for DEPDC1 in maintaining centrosome integrity during mitosis for the accurate distribution of chromosomes. Copyright © 2017. Published by Elsevier Inc.

  12. A study on international nuclear organizations and conventions for the globalization of Korean nuclear community

    International Nuclear Information System (INIS)

    Lee, Kwang Seok; Oh, Keun Bae; Lee, Byung Wook; Cho, Il Hoon; Lee, Jae Sung; Choi, Young Rok; Ko, Han Seok; Ham, Chul Hoon; Lee, Byung Woon

    1995-12-01

    The objective of this study is to analyze the current status of international nuclear organizations and conventions in systems perspective and suggest national strategies for utilizing them for the globalization of Korean nuclear community. This study analyzes the current status of international nuclear organizations such as IAEA(International Atomic Energy Agency) and international nuclear conventions related to nuclear accidents, nuclear liability, physical protection or nuclear safety. Based on the analysis, this study suggests national strategies, in general and specific terms, to utilize international nuclear organizations and conventions for the globalization of Korean nuclear community. Separately from this report this study publishes 'IAEA Handbook', which contains all about IAEA such as statute, membership, organizational structure, main activities, finance and budget, etc.. 9 tabs., 2 figs., 35 refs. (Author)

  13. Nuclear operations summary Engineering organization for Plowshare nuclear operations

    International Nuclear Information System (INIS)

    Broadman, Gene A.

    1970-01-01

    The availability of nuclear explosives for peaceful projects has given the engineer a new dimension in his thinking. He can now seek methods of adapting Plowshare to a variety of industrial applications. The full potential of the Plowshare Program can only be attained when industry begins to use nuclear explosives on a regular basis, for economically sound projects. It is the purpose of this paper to help the engineer familiarize himself with Plowshare technology to hasten the day when 'Plowsharee goes commercial'. An engineering project utilizing nuclear exposives ordinarily involves three main phases: Phase I (a) The theoretical and empirical analysis of effects. (b) Projected economic and/or scientific evaluation. (c) A safety analysis. Phase II (a) Field construction. (b) Safe detonation of the nuclear explosive. (c) Data acquisition. Phase III The evaluation and/or exploitation of the results. This paper will be restricted to Phase II, referred to collectively as the 'nuclear operation'

  14. Guidebook on training to establish and maintain the qualification and competence of nuclear power plant operations personnel

    International Nuclear Information System (INIS)

    1994-03-01

    Since the IAEA published its Guidebook on the Qualification of Nuclear Power Plant Operations Personnel in 1984 (Technical Reports Series 242) there have been important developments in the approach to training adopted by many operating organizations in different countries. It is now accepted that developing training programmes based solely on experience is inappropriate for the nuclear power industry, and that a systematic approach to training is necessary. It has been recognized that inadequate knowledge and skills may lead to human errors, and it is therefore necessary to review and improve the development and implementation of initial and continuing training programmes. The present Guidebook proposes an approach which is comprehensive and systematic in its methodology and also cost effective in its implementation. This Guidebook is mainly intended for management and training staff of nuclear power plant operating organizations. Relevant examples of current training practices are presented in the Appendices, which constitute an integral part of the Guidebook. Ref, figs and tabs

  15. Guidebook on training to establish and maintain the qualification and competence of nuclear power plant operations personnel

    International Nuclear Information System (INIS)

    1989-11-01

    Since the IAEA published its Guidebook on the Qualification of Nuclear Power Plant Operations Personnel in 1984 (Technical Reports Series 242) there have been important developments in the approach to training adopted by many operating organizations in different countries. It is now accepted that developing training programmes based solely on experience is inappropriate for the nuclear power industry, and that a systematic approach to training is necessary. It has been recognized that inadequate knowledge and skills may lead to human errors, and it is therefore necessary to review and improve the development and implementation of initial and continuing training programmes. The present Guidebook proposes an approach which is comprehensive and systematic in its methodology and also cost effective in its implementation. This Guidebook is mainly intended for management and training staff of nuclear power plant operating organizations. Relevant examples of current training practices are presented in the Appendices, which constitute an integral part of the Guidebook. Refs, figs and tabs

  16. Experiences from maintaining the reliability of a nuclear standby diesel generator system

    International Nuclear Information System (INIS)

    Tammi, P.

    1982-01-01

    The nuclear standby diesel generator system is quite complicated comprising several mechanical and electrotechnical components, on which the reliability of the system is depending. It is an important support system of the plant safety system, and like the safety system it is composed of separate redundant units. The Loviisa nuclear power station has eight diesel generators. The first four of them were taken into operation in 1976. When the frequency of some mechanical failures showed increase, a project was started at the end of 1980 with the intention to find out potential failure possibilities and means for prevention of failures. The work has been mainly concentrated on improving the reliability of the diesel engines. (Auth.)

  17. I and C and control room challenges and opportunities for maintaining and modernizing nuclear power plants

    International Nuclear Information System (INIS)

    Naser, J.

    2006-01-01

    Instrumentation and Control (I and C) systems and capabilities affect all areas of plant operation and can profoundly impact plant reliability, efficiency, and operating costs. Nuclear power plants are having problems with aging and obsolete equipment. These problems will get worse as plants age. The longer life resulting from license extension just increases the problems. Work is being done in the industry to optimize or extend the useful life and reliability of existing equipment and systems. However; long-term maintenance of aging and obsolete equipment is often not a viable option and modernization must also be considered. The Electric Power Research Inst. I and C Program has been working with its member utilities and other stakeholders in the nuclear power industry to: 1) enable nuclear power plants to support existing components and systems, 2) make improvements via component upgrades, 3) make system level improvements, and 4) plan for and initiate large scale upgrades to I and C systems and control rooms. Considerable progress has been made in both technical and regulatory areas to enable more cost-effective operation and maintenance and to take advantage of improvements possible with digital technology. However, there are still several challenges that must be addressed and several beneficial opportunities that are possible. Some are these areas are currently being addressed in the EPRI I and C Program. For many of the areas, the issues and solutions apply to new plants as well. (authors)

  18. Maintaining the safe operation of U.S. nuclear power plants

    International Nuclear Information System (INIS)

    Skavdahl, R.E.

    1991-01-01

    The more than one hundred nuclear power plants in the U.S. are a vital resource that provides about 20% of the electrical power production. Although about half the plants are more than 15 years old, there is no evidence of age-related deterioration in any of the key indicators of industry performance; indeed, the continuing improvement in all these indicators shows the industry is maturing, not growing old. The Institute for Nuclear Power Operations's performance assessment and training programs have spurred a heavy industry-wide commitment to improved training. These efforts are the key to excellence in the performance of operations and maintenance personnel. The interface between the reactor and the operator has been improved through control room design reviews, the implementation of a Safety Parameter Display System, and emergency procedure guidelines. These improvements ensure that the operators will be able to perform their functions under any circumstances they may encounter. Led by NUMARC, the industry initiative to improve plant maintenance programs incorporates such elements as the INPO performance standards, enhanced monitoring through the use of the Nuclear Plant Reliability Data System, Reliability Centered Maintenance, and improvements in plant technical specifications. These elements bring the latest available technology to plant maintenance programs. Equipment replacements are frequently made to take advantage of improvements in technology. Aside from the performance enhancements they offer, such replacements also serve to keep the plants young. By leveraging their resources through the owners groups, utilities are able to quickly and efficiently solve problems together that they could not afford to attack individually. Even the highly unlikely hypothetical severe accidents are addressed in a systematic fashion through the application of Probabilistic Risk Assessments. 15 figs

  19. Technical Support Organization Knowledge Management for Nuclear Regulatory Support

    International Nuclear Information System (INIS)

    Kohut, P.; Ramsey, J.; Katsenelenbogen, S.

    2016-01-01

    Full text: Knowledge management awareness has increased through the nuclear industrial and regulatory community leading to better understanding of the handling of critical information. Utilizing, managing and regulating the application of nuclear power require an extensive system of expertise and associated research through established organizations. The long term maintenance of the specific expertise is only viable by using scientific knowledge management principles all through the national nuclear infrastructure involving regulatory, industrial, academic and other research institutions. National governments in countries operating or planning to establish nuclear facilities have instituted regulatory regimes on the use of nuclear materials and facilities to insure a high level of operational safety. (author

  20. Investigation of the organic matter in inactive nuclear tank liquids

    International Nuclear Information System (INIS)

    Schenley, R.L.; Griest, W.H.

    1990-08-01

    Environmental Protection Agency (EPA) methodology for regulatory organics fails to account for the organic matter that is suggested by total organic carbon (TOC) analysis in the Oak Ridge National Laboratory (ORNL) inactive nuclear waste-tank liquids and sludges. Identification and measurement of the total organics are needed to select appropriate waste treatment technologies. An initial investigation was made of the nature of the organics in several waste-tank liquids. This report details the analysis of ORNL wastes

  1. How a disordered ubiquitin ligase maintains order in nuclear protein homeostasis.

    Science.gov (United States)

    Rosenbaum, Joel C; Gardner, Richard G

    2011-01-01

    Cells use protein quality control (PQC) systems to protect themselves from potentially harmful misfolded proteins. Many misfolded proteins are repaired by molecular chaperones, but irreparably damaged proteins must be destroyed. Eukaryotes predominantly destroy these abnormally folded proteins through the ubiquitin-proteasome pathway, which requires compartment-specific ubiquitin ligase complexes that mark substrates with ubiquitin for proteasome degradation. In the yeast nucleus, misfolded proteins are targeted for degradation by the ubiquitin ligase San1, which binds misfolded nuclear proteins directly and does not appear to require chaperones for substrate binding. San1 is also remarkably adaptable, as it is capable of ubiquitinating a structurally diverse assortment of abnormally folded substrates. We attribute this adaptability to San1's high degree of structural disorder, which provides flexibility and allows San1 to conform to differently shaped substrates. Here we review our recent work characterizing San1's distinctive mode of substrate recognition and the associated implications for PQC in the nucleus.

  2. More efficient integrated safeguards by applying a reasonable detection probability for maintaining low presence probability of undetected nuclear proliferating activities

    International Nuclear Information System (INIS)

    Otsuka, Naoto

    2013-01-01

    Highlights: • A theoretical foundation is presented for more efficient Integrated Safeguards (IS). • Probability of undetected nuclear proliferation activities should be maintained low. • For nations under IS, the probability to start proliferation activities is very low. • The fact can decrease the detection probability of IS by dozens of percentage points. • The cost of IS per nation can be cut down by reducing inspection frequencies etc. - Abstract: A theoretical foundation is presented for implementing more efficiently the present International Atomic Energy Agency (IAEA) integrated safeguards (ISs) on the basis of fuzzy evaluation of the probability that the evaluated nation will continue peaceful activities. It is shown that by determining the presence probability of undetected nuclear proliferating activities, nations under IS can be maintained at acceptably low proliferation risk levels even if the detection probability of current IS is decreased by dozens of percentage from the present value. This makes it possible to reduce inspection frequency and the number of collected samples, allowing the IAEA to cut costs per nation. This will contribute to further promotion and application of IS to more nations by the IAEA, and more efficient utilization of IAEA resources from the viewpoint of whole IS framework

  3. Local panels and maintainability human factors assessment for AP1000 nuclear power plant

    International Nuclear Information System (INIS)

    Li, Zhonghai; Reed, Julie I.

    2011-01-01

    A document entitled 'AP1000 Local Panels and Maintainability Human Factors Design Guidelines' was produced to aid the designers to specifically include human factors (HF) considerations in the design, operation, and maintenance of local control stations and plant equipment. To ensure that the applicable HF design guidelines are appropriately applied to the design of local panels and maintenance activities, and identify any HF improvement opportunities that can readily be implemented at the design stage, a HF assessment of maintenance activities and local plant operations is underway. This assessment gives priority to local control stations and equipment which have been identified as having a potential impact on safety. This includes risk-significant systems, structures and components (SSCs) identified through the probabilistic risk assessment (PRA), and local operator actions as required by the Emergency Operating Procedures (EOPs). Local actions, maintenance activities and associated operator interfaces are reviewed against the relevant HF guidelines. The results of the assessment include a description of the component, associated local actions and/or required maintenance activities, good design features and/or potential issues, and recommendations for change or improvement. These results are communicated to responsible design engineers who evaluate the impact to plant design and implement design changes, if deemed necessary. (author)

  4. Threedimensional imaging of organ structures by nuclear magnetic resonance

    International Nuclear Information System (INIS)

    Waters, W.; Smolorz, J.; Wellner, U.

    1985-01-01

    A simple method for threedimensional imaging of organ structures is presented. The method is based on a special acquisition mode in a nuclear resonance tomograph, exciting layers of 20 cm thickness at different angulations. The display is done by cinematography (which is usually used in nuclear cardiology) projecting the structures in a rotating movement. (orig.) [de

  5. Radiation protection organization in Guangdong Nuclear Power Station (GNPS)

    International Nuclear Information System (INIS)

    Yang Maochun

    1993-01-01

    The French way of radiation protection management has been adopted by Guangdong Nuclear Power Station (GNPS) but there are some differences. In this paper author describes radiation protection organization in GNPS, special measures having been taken and the present status

  6. Risk management of knowledge loss in nuclear industry organizations (Russian edition)

    International Nuclear Information System (INIS)

    2012-08-01

    Maintaining nuclear competencies in the nuclear industry and nuclear regulatory authorities will be one of the most critical challenges in the near future. As many nuclear experts around the world are retiring, they are taking with them a substantial amount of knowledge and corporate memory. The loss of such employees who hold knowledge critical to either operations or safety poses a clear internal threat to the safe and reliable operation of nuclear facilities. This publication is intended for senior and middle level managers of nuclear industry operating organizations and provides practical information on knowledge loss risk management. The information provided in this it is based upon the actual experiences of Member State operating organizations and is intended to increase awareness of the need to: develop a strategic approach and action plans to address the potential loss of critical knowledge and skills; provide processes and in conducting risk assessments to determine the potential for loss of critical knowledge caused by the loss of experienced workers; and enable nuclear organizations to utilize this knowledge to improve the skill and competence of new and existing workers In 2004, the IAEA published a report entitled The Nuclear Power Industry's Ageing Workforce: Transfer of Knowledge to the Next Generation (IAEA-TECDOC-1399). That report highlighted some of the knowledge management issues in Member States resulting from the large number of retiring nuclear power plant personnel who had been involved with the commissioning and initial operation of nuclear power plants. This publication complements that report by providing a practical methodology on knowledge loss risk management as one element of an overall strategic approach to workforce management which includes work force planning, recruitment, training, leadership development and knowledge retention

  7. Sustainable Transformation & Effective Competency Management Practices in Nuclear Organizations

    International Nuclear Information System (INIS)

    Gardelliano, S.

    2016-01-01

    Full text: Managing essential knowledge as a strategic organizational asset is a factor of upmost relevance in today’s nuclear organizations. The author considers evident that competencies are critical carriers of knowledge. As such the use of an appropriate competency model could be the most effective way to capture the present reservoir of explicit and tacit Knowledge of specific functions or organizational areas. Besides, we could use them for new or other redesigned functions or determine the needs of specific competencies for future positions. Therefore, appropriate competency models or systems have to be developed or updated in each nuclear organization since these are fundamental for managing more effectively and efficiently the present nuclear human capital and to forecast the evolving competence required in management, technical, scientific and safety areas to continuously ensure a highly competent nuclear workforce. On the other hand, competency based management models or systems would not achieve the expected results if they are not fully designed and integrated within the strategic organizational infrastructure of the related nuclear organization. This paper is expected to provide a wider view and practical reflections on organizational transformation issues and the benefits of using an integrative competency model in the nuclear industry. Particularly, the paper give an insight of an empiric model for strategic organizational transformation processes and integrative management practices, and on how to realign strategic issues with top management processes and build organizational capacity through effective competency based management for the sustainable transformation of nuclear organizations. (author

  8. The U.S. Nuclear Regulatory Commission Thermal-Hydraulic Research Program: Maintaining expertise in a changing environment

    International Nuclear Information System (INIS)

    Sheron, B.W.; Shotkin, L.M.; Baratta, A.J.

    1993-01-01

    Throughout the 1970s and early 1980s, the U.S. Nuclear Regulatory Commission's (NRC's) thermal-hydraulic research program enjoyed ample funding, sponsored extensive experimental and analytical development programs, and attracted worldwide expertise. With the completion of the major experimental programs and with the promulgation of the revised emergency core-cooling system rule, both the funding and prominence of thermal-hydraulic research at the NRC have declined in recent years. This has led justifiably to the concern by some that the program may no longer have the minimal elements needed to maintain both expertise and world-class status. The purpose of this article is to describe the NRC's current thermal-hydraulic research program and to show how this program ensures maintenance of a viable, robust research effort and retention of needed expertise and international leadership

  9. US Nuclear Regulatory Commission organization charts and functional statements

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    This document contains organization charts for the U.S. Nuclear Regulatory Commission (NRC) and for the five offices of the NRC. Function statements are provided delineating the major responsibilities and operations of each office. Organization and function are provided to the branch level. The head of each office, division, and branch is also listed.

  10. US Nuclear Regulatory Commission organization charts and functional statements

    International Nuclear Information System (INIS)

    1997-01-01

    This document contains organization charts for the U.S. Nuclear Regulatory Commission (NRC) and for the five offices of the NRC. Function statements are provided delineating the major responsibilities and operations of each office. Organization and function are provided to the branch level. The head of each office, division, and branch is also listed

  11. The organization of nuclear plants environmental studies

    International Nuclear Information System (INIS)

    Le Marechal, M.

    1980-01-01

    The author first defines the objectives of environmental studies. Next, he describes the scope and organization of sites studies as well as biological and radioecological general studies. At last, he puts forward the available means that are used for such studies and the different offices responsible for their achievement [fr

  12. Autophagy is essential for maintaining the growth of a human (mini-)organ: Evidence from scalp hair follicle organ culture.

    Science.gov (United States)

    Parodi, Chiara; Hardman, Jonathan A; Allavena, Giulia; Marotta, Roberto; Catelani, Tiziano; Bertolini, Marta; Paus, Ralf; Grimaldi, Benedetto

    2018-03-28

    Autophagy plays a crucial role in health and disease, regulating central cellular processes such as adaptive stress responses, differentiation, tissue development, and homeostasis. However, the role of autophagy in human physiology is poorly understood, highlighting a need for a model human organ system to assess the efficacy and safety of strategies to therapeutically modulate autophagy. As a complete, cyclically remodelling (mini-)organ, the organ culture of human scalp hair follicles (HFs), which, after massive growth (anagen), spontaneously enter into an apoptosis-driven organ involution (catagen) process, may provide such a model. Here, we reveal that in anagen, hair matrix keratinocytes (MKs) of organ-cultured HFs exhibit an active autophagic flux, as documented by evaluation of endogenous lipidated Light Chain 3B (LC3B) and sequestosome 1 (SQSTM1/p62) proteins and the ultrastructural visualization of autophagosomes at all stages of the autophagy. This autophagic flux is altered during catagen, and genetic inhibition of autophagy promotes catagen development. Conversely, an anti-hair loss product markedly enhances intrafollicular autophagy, leading to anagen prolongation. Collectively, our data reveal a novel role of autophagy in human hair growth. Moreover, we show that organ-cultured scalp HFs are an excellent preclinical research model for exploring the role of autophagy in human tissue physiology and for evaluating the efficacy and tissue toxicity of candidate autophagy-modulatory agents in a living human (mini-)organ.

  13. Organization and development of the Brazilian nuclear program

    International Nuclear Information System (INIS)

    Pinto, C. Syllus M.; Alves, R. Nazare; Lepecki, W.; Costa, H.M. da; Grinberg, M.; Grimberg, M.

    1977-01-01

    The paper presents the Brazilian Nuclear Energy Program: its development until the present stage, as well as the organizations and the distribution of responsibilities involved in its execution at the present time. The nuclear power policy is established at the Presidency of the Republic and is planned, executed and controlled through the Ministry of Mines and Energy. Directly subject to the Ministry is the Brazilian Nuclear Energy Commission (CNEN), which has regulatory, standardization, licensing, planning and surveillance functions. The nuclear fundamental research and manpower formation are also under CNEN responsibility. Also subject to the Ministry are two companies responsible for the execution of the Programme: the Centrais Eletricas Brasileiras S.A. - ELETROBRAS, which advises on the granting of permits for the construction and operation of nuclear power plants, and the Empresas Nucleares Brasileiras S.A. - NUCLEBRAS, which holds the monopoly of the nuclear fuel cycle in the country, designs and builds nuclear power plants and provides assistance to the electric utilities as well as promotes the participation of the Brazilian industry in the nuclear field. Besides describing the new distribution of regulatory functions given by law to the CNEN, this paper gives special emphasis to the large industrial complex which is in the process of being established with the setting-up of the many NUCLEBRAS subsidiaries in joint-venture with German firms in the nuclear field, as a consequence of the Industrial Cooperation between Brazil and the Federal Republic of Germany in the Field of the Peaceful Uses of Nuclear Energy signed between the two countries on June 27, 1975. The programs for these subsidiaries are presented and their participation in the Brazilian Nuclear Energy Programme is discussed. The technology transfer aspects of the industrial activities are also discussed, based on the Government's policy on the subject [es

  14. Organization of the operating quality in EDF nuclear power stations

    International Nuclear Information System (INIS)

    Stolz, J.

    1976-01-01

    The organization of operating quality in EDF nuclear stations cover a number of planned and systematic actions of technical and management order carried on at station level and Nuclear Safety Department level. Priority is given to safety quality which has to remain the same during the whole life of the stations; the safety of a station depending from its designing, realization and starting up quality on one hand and from its operating methods on the other [fr

  15. The Role of Performance Management in Creating and Maintaining a High-Performance Organization

    NARCIS (Netherlands)

    Waal, A.A. de; Heijden, B.I.J.M. van der

    2015-01-01

    There is still a good deal of confusion in the literature about how the use of a performance management system affects overall organizational performance. Some researchers find that performance management enhances both the financial and non-financial results of an organization, while others do not

  16. Shallow non-inversion tillage in organic farming maintains crop yields and increases soil C stocks

    NARCIS (Netherlands)

    Cooper, Julia; Baranski, Marcin; Stewart, Gavin; Nobel-de Lange, Majimcha; Bàrberi, Paolo; Fließbach, Andreas; Peigné, Josephine; Berner, Alfred; Brock, Christopher; Casagrande, Marion; Crowley, Oliver; David, Christophe; Vliegher, De Alex; Döring, Thomas F.; Dupont, Aurélien; Entz, Martin; Grosse, Meike; Haase, Thorsten; Halde, Caroline; Hammerl, Verena; Huiting, Hilfred; Leithold, Günter; Messmer, Monika; Schloter, Michael; Sukkel, Wijnand; Heijden, van der Marcel G.A.; Willekens, Koen; Wittwer, Raphaël; Mäder, Paul

    2016-01-01

    Reduced tillage is increasingly promoted to improve sustainability and productivity of agricultural systems. Nonetheless, adoption of reduced tillage by organic farmers has been slow due to concerns about nutrient supply, soil structure, and weeds that may limit yields. Here, we compiled the

  17. Corporation as Civil Organization in a CSR Campaign: The Challenge of Maintaining Credibility

    DEFF Research Database (Denmark)

    Trapp, Leila

    2011-01-01

    are recognized and maintained in CSR campaigns, challenges to a company’s credibility and reputation can arise. Key words: corporate social responsibility, corporate communication, cross-sector partnerships, corporate sustainability, campaigns, collaboration Paper type: case study Googins, B. K., Rochlin, S. A......CSR understandings and practices, including ways corporations communicate about CSR, are in constant flux due to innovation and changing stakeholder expectations, which in turn are influenced by inevitable changes in social, political and economic circumstances. In this paper, focus...... in on the growing expectation that companies address large, global issues (Stohl, Stohl & Popova, 2009). Through a case study of a unique and innovative CSR campaign that addresses global climate change, this paper revisits the understanding of CSR as a shift in roles and responsibilities between corporations...

  18. Organization of the internal dosimetry in the Spanish nuclear facilities

    International Nuclear Information System (INIS)

    Manchena, P.; Soliet, E.

    1998-01-01

    From the beginning of the exploitation of the nuclear energy of Espanna, the nuclear facilities have had Services of Personal Dosimetry with the appropriate means to determine the dose. so much internal as external, of the personnel that mentioned facilities works. All the nuclear power stations use advanced systems of teams with object of detecting the radionuclides incorporation in the organism and calculation programs based on the recent recommendations of the International Commission of Radiological Protection (ICRP) for the determination of the derived doses

  19. Management and organization in nuclear power plant safety

    International Nuclear Information System (INIS)

    Osborn, R.N.

    1983-08-01

    In the immediate aftermath of the Three Mile Island accident, the Nuclear Regulatory Commission-sponsored investigations of the relation between human issues and safety tended to focus on individual and, at most, group level phenomena. This initial bottom up view of organizational safety has continued to be investigated by the Nuclear Regulatory Commission, as evidence by the four previous papers. Recently, however, work has begun which adopts a top down management/organization approach to nuclear power plant safety. This paper reports on the research, to date, on this focus

  20. Contribution of IAEA, FNRBA and ANNuR as Networking in Developing and Maintaining Capacity Building for a nuclear power programme: Comparative study

    International Nuclear Information System (INIS)

    Osman, Omer E.

    2014-01-01

    It is increasingly recognised that the mobilization and exchange of knowledge between different sectors (such as academia, policymakers, Regulators and practitioners) and regions or global can be of paramount importance in the field of Capacity Building for a nuclear power programme. As a result, the number of knowledge networks in this field has risen dramatically in recent years. Some of these networks bring together actors within a specific region, such as European Nuclear Safety Regulators Group (ENSREG), Western European Nuclear Regulators Association (WENRA), The Arab Network of Nuclear Regulators (ANNuR). Still others cover entire continents such as Asian Nuclear Safety Network (ANSN), Asia Pacific Safeguards Network (APSN) and Forum of Nuclear Regulatory Bodies in Africa (FNRBA). Or even operate worldwide and globally, like IAEA Special Support Services, Global Nuclear Safety and Security Network (GNSSN), World Organization of Nuclear Operators (WANO) and International Nuclear Regulators Association (INRA)

  1. Organization model and formalized description of nuclear enterprise information system

    International Nuclear Information System (INIS)

    Yuan Feng; Song Yafeng; Li Xudong

    2012-01-01

    Organization model is one of the most important models of Nuclear Enterprise Information System (NEIS). Scientific and reasonable organization model is the prerequisite that NEIS has robustness and extendibility, and is also the foundation of the integration of heterogeneous system. Firstly, the paper describes the conceptual model of the NEIS on ontology chart, which provides a consistent semantic framework of organization. Then it discusses the relations between the concepts in detail. Finally, it gives the formalized description of the organization model of NEIS based on six-tuple array. (authors)

  2. Knowledge Loss: A Defensive Model In Nuclear Research Organization Memory

    International Nuclear Information System (INIS)

    Mohamad Safuan Bin Sulaiman; Muhd Noor Muhd Yunus

    2013-01-01

    Knowledge is an essential part of research based organization. It should be properly managed to ensure that any pitfalls of knowledge retention due to knowledge loss of both tacit and explicit is mitigated. Audit of the knowledge entities exist in the organization is important to identify the size of critical knowledge. It is very much related to how much know-what, know-how and know-why experts exist in the organization. This study conceptually proposed a defensive model for Nuclear Malaysia's organization memory and application of Knowledge Loss Risk Assessment (KLRA) as an important tool for critical knowledge identification. (author)

  3. Lineage restriction maintains a stable organizer cell population at the zebrafish midbrain-hindbrain boundary.

    Science.gov (United States)

    Langenberg, Tobias; Brand, Michael

    2005-07-01

    The vertebrate hindbrain is subdivided into segments, termed neuromeres, that are units of gene expression, cell differentiation and behavior. A key property of such segments is that cells show a restricted ability to mix across segment borders -- termed lineage restriction. In order to address segmentation in the midbrain-hindbrain boundary (mhb) region, we have analyzed single cell behavior in the living embryo by acquiring time-lapse movies of the developing mhb region in a transgenic zebrafish line. We traced the movement of hundreds of nuclei, and by matching their position with the expression of a midbrain marker, we demonstrate that midbrain and hindbrain cells arise from two distinct cell populations. Single cell labeling and analysis of the distribution of their progeny shows that lineage restriction is probably established during late gastrulation stages. Our findings suggest that segmentation as an organizing principle in early brain development can be extended to the mhb region. We argue that lineage restriction serves to constrain the position of the mhb organizer cell population.

  4. The Ubiquitin Ligase CBLC Maintains the Network Organization of the Golgi Apparatus.

    Directory of Open Access Journals (Sweden)

    Wan Yin Lee

    Full Text Available The Golgi apparatus plays a pivotal role in the sorting and post-translational modifications of secreted and membrane proteins. In mammalian cells, the Golgi is organized in stacks of cisternae linked together to form a network with a ribbon shape. Regulation of Golgi ribbon formation is poorly understood. Here we find in an image-based RNAi screen that depletion of the ubiquitin-ligase CBLC induces Golgi fragmentation. Depletions of the close homologues CBL and CBLB do not induce any visible defects. In CBLC-depleted cells, Golgi stacks appear relatively unperturbed at both the light and electron microscopy levels, suggesting that CBLC controls mostly network organization. CBLC partially localizes on Golgi membranes and this localization is enhanced after activation of the SRC kinase. Inhibition of SRC reverts CBLC depletion effects, suggesting interplay between the two. CBLC's regulation of Golgi network requires its ubiquitin ligase activity. However, SRC levels are not significantly affected by CBLC, and CBLC knockdown does not phenocopy SRC activation, suggesting that CBLC's action at the Golgi is not direct downregulation of SRC. Altogether, our results demonstrate a role of CBLC in regulating Golgi ribbon by antagonizing the SRC tyrosine kinase.

  5. Communication challenges in the perspective of nuclear organizations in Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Machado, Tariana Brocardo, E-mail: tariana@usp.br [Universidade de São Paulo (USP), SP (Brazil). Escola de Comunicações e Artes

    2017-07-01

    The aim of this paper is to discuss the results of a study which reveals the communication challenges faced by organizations of the nuclear segment in Brazil towards its public acceptance. This is a descriptive study with qualitative approach based on primary data collection made through interview with non-probabilistic sample and categorical content analysis as method. The study was carried out with managers, technicians and communicators of three representative organizations of the segment in the country – CNEN, Eletronuclear and IPEN – in the period ranging from October, 2015, to March, 2016, as part of a greater study composing the author’s Master’s dissertation presented at Universidade de São Paulo in October, 2016. As results, the main communication challenges spotted by nuclear professionals in Brazil are lack of public acceptance of the nuclear energy in the country, followed by low levels of communication of the benefits of the nuclear field, lack of budget for investing in communication strategy and activities and institutional bureaucracy, as well as political motives and professionals being politically appointed for holding communication positions. Other communication-related challenges faced by the nuclear field in Brazil mentioned by interviewees include employees without adequate amount of time to dedicate to communication or unfit for this specific work, excessive use of technical language, discredit of the nuclear area within local society, lack of interest by the media and difficulty for hiring new communication professionals. This research was financially supported by CAPES. 1. (author)

  6. Communication challenges in the perspective of nuclear organizations in Brazil

    International Nuclear Information System (INIS)

    Machado, Tariana Brocardo

    2017-01-01

    The aim of this paper is to discuss the results of a study which reveals the communication challenges faced by organizations of the nuclear segment in Brazil towards its public acceptance. This is a descriptive study with qualitative approach based on primary data collection made through interview with non-probabilistic sample and categorical content analysis as method. The study was carried out with managers, technicians and communicators of three representative organizations of the segment in the country – CNEN, Eletronuclear and IPEN – in the period ranging from October, 2015, to March, 2016, as part of a greater study composing the author’s Master’s dissertation presented at Universidade de São Paulo in October, 2016. As results, the main communication challenges spotted by nuclear professionals in Brazil are lack of public acceptance of the nuclear energy in the country, followed by low levels of communication of the benefits of the nuclear field, lack of budget for investing in communication strategy and activities and institutional bureaucracy, as well as political motives and professionals being politically appointed for holding communication positions. Other communication-related challenges faced by the nuclear field in Brazil mentioned by interviewees include employees without adequate amount of time to dedicate to communication or unfit for this specific work, excessive use of technical language, discredit of the nuclear area within local society, lack of interest by the media and difficulty for hiring new communication professionals. This research was financially supported by CAPES. 1. (author)

  7. Studies on the effectiveness of measures to maintain the integrity of pressurized components in German nuclear power plants. Final report

    International Nuclear Information System (INIS)

    Elmas, M.; Jendrich, U.; Michel, F.; Reck, H.; Schimpfke, T.; Walter, M.; Wenke, R.

    2013-03-01

    The overall objective of the project was to investigate the effectiveness of measures to maintain the as-built quality of the pressure-retaining components in German nuclear power plants. In particular, investigations were performed on the application of the break preclusion concept, existing monitoring systems and the significance of the pressure test as part of the inspection concept. Moreover, the KompInt knowledge base has been updated. Break preclusion for pipes was applied in all German plants already during planning or after commissioning to a varying extent. The basic features of the required assessments were considered in the German nuclear regulations for the first time by inclusion in the safety requirements for nuclear power plants of 2012. The requirements for assessments, differing in their degree of detail, in the interpretations of these safety requirements and in the safety standard KTA 3206 are still in the draft stage. For the first time, the vessels as well as housings of valves and pumps are also included in the concept. Through the use of advanced monitoring systems it was possible in German plants at an early stage to establish modes of operation that minimise the load on components, to carry out appropriate technical backfitting measures, and to identify damages. In plant areas where local water chemistry parameters may result that deviate from the specification, the effectiveness of water chemistry monitoring is limited. In this case, other operational measures must be taken. The results of the simulations performed with the help of the GRS-developed PROST computer code to determine the significance of pressure tests lead - in accordance with the results of operating experience evaluation - to the conclusion that pressure tests carried out within the pressure-retaining boundary contribute to safeguarding the integrity. The user-friendliness of the KompInt knowledge base has been increased by changing over to a new hardware, a software

  8. Organic Pollutants in Soils, as Studied by Nuclear Magnetic Resonance

    Science.gov (United States)

    1998-05-15

    fundamental behaviors of certain organic pollutants (e.g., benzene, CC1, trichloroethylene, ethylene glycol) when adsorbed in typical soils , as...represented in most of this study by the ’ following major soil components: humics (humic acid, fulvic acid, humin ), clays (montmorillonite, kaolinite...239.18 Designed using Perform Pro, WHS/DIOR, Oct 94 • • 2 2 NAY m^ FINAL TECHNICAL REPORT ORGANIC POLLUTANTS IN SOILS , AS STUDIED BY NUCLEAR

  9. Receptor activator of nuclear factor-κB ligand and osteoprotegerin: maintaining the balance to prevent bone loss

    Directory of Open Access Journals (Sweden)

    Anne-Priscille Trouvin

    2010-11-01

    Full Text Available Anne-Priscille Trouvin, Vincent GoëbDepartment of Rheumatology, Rouen University Hospital, Rouen, FranceAbstract: Bone remodeling requires a precise balance between resorption and formation. It is a complex process that involves numerous factors: hormones, growth factors, vitamins, and cytokines, and notably osteoprotegerin (OPG and receptor activator for nuclear factor-κB (RANK ligand. The signaling pathway OPG/RANK/RANKL is key to regulation for maintaining the balance between the activity of osteoblasts and osteoclasts in order to prevent bone loss and ensure a normal bone turnover. In this review, the RANK/RANKL/OPG pathway is described. The multiple interactions of various factors (hormones, cytokines, growth factors, and vitamins with the OPG/RANK/RANKL pathway are also commented on. Finally, the effects of denosumab, a human monoclonal antibody that binds to RANKL and thereby inhibits the activation of osteoclasts, and of strontium ranelate are also described. Indeed, these two new drugs afford appreciable assistance in daily care practice, helping to prevent bone loss in patients with osteoporosis.Keywords: osteoprotegerin, OPG, RANK, RANKL, denosumab, strontium ranelate, osteoporosis

  10. A decade of 3C technologies: insights into nuclear organization

    NARCIS (Netherlands)

    de Wit, E.; de Laat, W.

    2012-01-01

    Over the past 10 years, the development of chromosome conformation capture (3C) technology and the subsequent genomic variants thereof have enabled the analysis of nuclear organization at an unprecedented resolution and throughput. The technology relies on the original and, in hindsight, remarkably

  11. PROXIMAL AND DISTAL FACTORS ASSOCIATED WITH DROPOUT VERSUS MAINTAINED PARTICIPATION IN ORGANIZED SPORT

    Directory of Open Access Journals (Sweden)

    Julie C.S. Boiché

    2009-03-01

    Full Text Available The purpose of this study was to investigate a large number of determinants of sport dropout among French adolescents, in order to reveal proximal and distal factors of dropout. 261 current and 106 dropout athletes (M = 14.6 participated to the study. The data were collected by a questionnaire assessing demographic information, athletes' perceptions on their experience, their parents, teammates and coach. t-tests revealed that current and former athletes were distinct on numerous variables. A discriminant function analysis showed three proximal predictors of sport dropout (perceived value of the activity, satisfaction, parents' investment. Subsequent regression analyses showed that perceived value was positively predicted by perceived competence, the value of the activity for teammates, coach's investment, and negatively by conflicts of interest and goal conflict with teammates; satisfaction was positively predicted by the coach's mastery climate, but negatively predicted by conflicts of interest and goal conflict with teammates and with the coach; parents investment was negatively predicted by the goal conflicts with them. This study permitted to discriminate between proximal and more distal psychological antecedents of the dropout behaviour. It brings information relative to the possible targets of interventions aiming at preventing dropout from organized sport

  12. Organizing irresponsibility? The (inter)national management of a nuclear accident damages as discursive regime

    International Nuclear Information System (INIS)

    Topcu, Sezin

    2014-01-01

    This article analyzes the historical process related to the international organization of responsibilities and the management of the damages in case of a nuclear disaster. The author shows that the political and legal settings on which the discourse of an 'international regime of civil responsibility' (that emerged in the 1960's) relies, have globally aimed at maintaining a 'historical and spectacular gap' between the damages the nuclear operators are taking responsibility for, and the real and extensive damages engendered by a major accident. She argues that the existence of such a 'gap' is inherent to the nuclear sector, that it is a form of government (both of economic affairs and of the public space) which was historically constructed, and that the existence of such a gap is crucial for the survival of the nuclear industry itself. Thus the notion of 'responsibility' in the nuclear sector appears to serve mainly as a discursive regime, as a means to organize not only responsibilities but also irresponsibilities, whatever the geographic scale (national or international) at which they should be managed

  13. The role of Nuclear Energy Unit in gathering, organizing and disseminating of nuclear information

    International Nuclear Information System (INIS)

    Samsurdin Ahamad

    1986-01-01

    The Nuclear Energy Unit (UTN) was established with an aim to promote the application of Nuclear Science and Technology in industries, agriculture and medicine in Malaysia. Therefore UTN represents Malaysia in INIS so as to share the available information for collection, merging and dissemination of information. In UTN a variety of activities are being carried out, especially by the Information Science Department whereby a library, equipped with reading materials and a computerized information system (SMBK) is set up as the information centre. A number of publications have also been made so as to keep the technical officers and other staff aware of the developments in Nuclear Science and Technology. To provide a better understanding of the latest techniques and nuclear technological procedures, courses, seminars and workshops for officers involved are carried out. Talks and exhibitions are also organized in order to promote Nuclear Science and Technology amongst the layman. (author)

  14. Capture of organic iodides from nuclear waste by metal-organic framework-based molecular traps.

    Science.gov (United States)

    Li, Baiyan; Dong, Xinglong; Wang, Hao; Ma, Dingxuan; Tan, Kui; Jensen, Stephanie; Deibert, Benjamin J; Butler, Joseph; Cure, Jeremy; Shi, Zhan; Thonhauser, Timo; Chabal, Yves J; Han, Yu; Li, Jing

    2017-09-07

    Effective capture of radioactive organic iodides from nuclear waste remains a significant challenge due to the drawbacks of current adsorbents such as low uptake capacity, high cost, and non-recyclability. We report here a general approach to overcome this challenge by creating radioactive organic iodide molecular traps through functionalization of metal-organic framework materials with tertiary amine-binding sites. The molecular trap exhibits a high CH 3 I saturation uptake capacity of 71 wt% at 150 °C, which is more than 340% higher than the industrial adsorbent Ag 0 @MOR under identical conditions. These functionalized metal-organic frameworks also serve as good adsorbents at low temperatures. Furthermore, the resulting adsorbent can be recycled multiple times without loss of capacity, making recyclability a reality. In combination with its chemical and thermal stability, high capture efficiency and low cost, the adsorbent demonstrates promise for industrial radioactive organic iodides capture from nuclear waste. The capture mechanism was investigated by experimental and theoretical methods.Capturing radioactive organic iodides from nuclear waste is important for safe nuclear energy usage, but remains a significant challenge. Here, Li and co-workers fabricate a stable metal-organic framework functionalized with tertiary amine groups that exhibits high capacities for radioactive organic iodides uptake.

  15. Capture of organic iodides from nuclear waste by metal-organic framework-based molecular traps

    KAUST Repository

    Li, Baiyan

    2017-09-01

    Effective capture of radioactive organic iodides from nuclear waste remains a significant challenge due to the drawbacks of current adsorbents such as low uptake capacity, high cost, and non-recyclability. We report here a general approach to overcome this challenge by creating radioactive organic iodide molecular traps through functionalization of metal-organic framework materials with tertiary amine-binding sites. The molecular trap exhibits a high CH3I saturation uptake capacity of 71 wt% at 150 °C, which is more than 340% higher than the industrial adsorbent Ag0@MOR under identical conditions. These functionalized metal-organic frameworks also serve as good adsorbents at low temperatures. Furthermore, the resulting adsorbent can be recycled multiple times without loss of capacity, making recyclability a reality. In combination with its chemical and thermal stability, high capture efficiency and low cost, the adsorbent demonstrates promise for industrial radioactive organic iodides capture from nuclear waste. The capture mechanism was investigated by experimental and theoretical methods.Capturing radioactive organic iodides from nuclear waste is important for safe nuclear energy usage, but remains a significant challenge. Here, Li and co-workers fabricate a stable metal-organic framework functionalized with tertiary amine groups that exhibits high capacities for radioactive organic iodides uptake.

  16. ICT in supporting Nuclear Malaysia as National Technical Support Organization

    International Nuclear Information System (INIS)

    Saaidi Ismail; Siti Nurbahyah Hamdan; Mohd Fauzi Haris

    2011-01-01

    Information and communication technology (ICT) services are basic requirements in any organization during this information age. ICT is proven as a powerful enabler in organization due to its unique characteristics that improve communication, collaboration, and the exchange of information to strengthen and create new economic and social networks. As Malaysian Nuclear Agency is moving towards Technical Support Organization (TSO), the importance of ICT cannot simply be ignored. Being a TSO for national Nuclear Power Plant (NPP), Nuclear Malaysia is responsible for providing the technical and scientific basis for decisions and activities regarding nuclear technology and radiation safety. As a TSO, Nuclear Malaysia should utilize and collaborate data and information available from it activities and programs and use it to expedite the implementation of national NPP. Technical support also responsible to contribute an excellent operation by providing technical inputs and support for optimizing NPP component (such as plant procedures, operation and maintenance, technical assistance, training etc). These tasks can be performed more effectively and efficiently with the help of appropriate ICT services and solution. Therefore, the deployment and implementation of appropriate ICT requirement shall be made to fulfill agency needs. As initial step, existing ICT facilities should be reassessed. This is because the capacity of existing ICT services is very limited in terms of manpower, infrastructure, and applications. This paper however, will briefly discuss only to the requirement gap on existing ICT manpower and infrastructure with the requirement needed for TSO. The facts then will be used to improve ICT manpower and infrastructure in Nuclear Malaysia to provide reliable and high availability of technical support for national NPP. (author)

  17. Organization, structure, and performance in the US nuclear power industry

    International Nuclear Information System (INIS)

    Lester, R.K.

    1986-01-01

    Several propositions are advanced concerning the effects of industry organization and structure on the economic performance of the American commercial nuclear power industry. Both the electric utility industry and the nuclear power plant supply industry are relatively high degree of horizontal disaggregation. The latter is also characterized by an absence of vertical integration. The impact of each of these factors on construction and operating performance is discussed. Evidence is presented suggesting that the combination of horizontal and vertical disaggregation in the industry has had a significant adverse effect on economic performance. The relationship between industrial structure and regulatory behavior is also discussed. 43 references, 4 figures, 9 tables

  18. The nature of expertise and human resource functions supporting expertise in nuclear industry organizations

    International Nuclear Information System (INIS)

    Rintala, N.; Katri, S.; Eila, J.; Pahkin, K.; Anneli, L.

    2007-01-01

    . Altogether approximately 25 interviews for experts will be conducted. The aim of these interviews is to disclose e.g. how the experts themselves describe their expertise and their expert role, what kind of support they need in maintaining and developing their expertise as well as what skills and skill sets they consider to be critical in the future. Approximately 5 interviews are carried out for managers. These interviews set out to explore the managers' role in allocating and designing human resources and their insights on the current HR practices supporting the development and preservation of expertise. About 3 HR representatives will be interviewed to uncover how HR functions, such as recruiting and training, operate currently. The HR functions that are used in the nuclear power organizations are then compared to HR process models and designs from the human resources management (HRM) literature. The study contributes to the HRM body of knowledge from a functional, micro level perspective, exploring the impacts of HR practices on individuals rather than on corporations or business units (a strategic, macro level perspective). Furthermore, rather than studying one individual HR practice, we treat multiple HR practices as a system in order to uncover how individual practices complement, substitute for, or even conflict with other practices. As a result, we expect to produce new understanding about the nature of expertise in the nuclear industry and discover new innovative ways to support the development, preservation and sharing of expertise. (author)

  19. Knowledge management as an approach to strengthen safety culture in nuclear organizations

    Energy Technology Data Exchange (ETDEWEB)

    Karseka, T.S.; Yanev, Y.L. [International Atomic Energy Agency, Vienna (Austria). Nuclear Energy Dept.

    2013-04-15

    In the last 10 years knowledge management (KM) in nuclear organizations has emerged as a powerful strategy to deal with important and frequently critical issues of attrition, generation change and knowledge transfer. Applying KM practices in operating organizations, in technical support organizations and regulatory bodies has proven to be efficient and necessary for maintaining competence and skills for achieving high level of safety and operational performance. The IAEA defines KM as an integrated, systematic approach to identifying, acquiring, transforming, developing, disseminating, using, sharing, and preserving knowledge, relevant to achieving specified objectives. KM focuses on people and organizational culture to stimulate and nurture the sharing and use of knowledge; on processes or methods to find, create, capture and share knowledge; and on technology to store and assimilate knowledge and to make it readily accessible in a manner which will allow people to work together even if they are not located together. A main objective of this paper is to describe constructive actions which can sponsor knowledge sharing and solidarity in safety conscious attitude among all employees. All principles and approaches refer primarily to Nuclear Power Plant (NPP) operating organizations but are also applicable to other institutions involved into nuclear sector. (orig.)

  20. Complex organizations: the case of the Brazilian nuclear sector

    Energy Technology Data Exchange (ETDEWEB)

    Xavier, Roberto Salles [Comissao Nacional de Energia Nuclear (CNEN), Rio de Janeiro, RJ (Brazil). Coordenacao-Geral de Planejamento e Avaliacao], e-mail: xavier@cnen.gov.br

    2009-07-01

    The resumption of the Brazilian Nuclear Program (BNP), in the proposed size and after 20 years of paralysis, requires profound changes in the current organizational modeling of the national nuclear industry. The effectiveness of any process of organizational change is limited to three factors. The theoretical bottleneck happens when you do not know enough about a phenomenon in order to effect the desired changes. The resource bottleneck occurs when knowledge may be available to change people's behavior but the funds necessary for implementation may be lacking. The organizational bottleneck emerges when there are knowledge and resources to solve a problem, but may not able to organize the resources in order to carry out the problem-solving effort. In the case of resumption of BNP seems clear that there is the knowledge of what is needed to make policy and the intention to allocate the necessary resources. But the question is the following: the current organizational model of the Brazilian nuclear sector is consistent with the goals laid down in the scenario of resumption of BNP? That is, is there organizational ability to leverage a program of the size proposed for the nuclear area? Find answers to these questions is crucial, because the organizational model of the Brazilian nuclear sector consists of elements involving a complex interorganizational system. Thus, this article is to examine the appropriateness of the current organizational modeling of the Brazilian nuclear sector to current demands of society. As a result, the article aims to propose recommendations for a remodeling of the nuclear sector, taking into account the current national and international scenarios of nuclear energy. (author)

  1. Complex organizations: the case of the Brazilian nuclear sector

    International Nuclear Information System (INIS)

    Xavier, Roberto Salles

    2009-01-01

    The resumption of the Brazilian Nuclear Program (BNP), in the proposed size and after 20 years of paralysis, requires profound changes in the current organizational modeling of the national nuclear industry. The effectiveness of any process of organizational change is limited to three factors. The theoretical bottleneck happens when you do not know enough about a phenomenon in order to effect the desired changes. The resource bottleneck occurs when knowledge may be available to change people's behavior but the funds necessary for implementation may be lacking. The organizational bottleneck emerges when there are knowledge and resources to solve a problem, but may not able to organize the resources in order to carry out the problem-solving effort. In the case of resumption of BNP seems clear that there is the knowledge of what is needed to make policy and the intention to allocate the necessary resources. But the question is the following: the current organizational model of the Brazilian nuclear sector is consistent with the goals laid down in the scenario of resumption of BNP? That is, is there organizational ability to leverage a program of the size proposed for the nuclear area? Find answers to these questions is crucial, because the organizational model of the Brazilian nuclear sector consists of elements involving a complex interorganizational system. Thus, this article is to examine the appropriateness of the current organizational modeling of the Brazilian nuclear sector to current demands of society. As a result, the article aims to propose recommendations for a remodeling of the nuclear sector, taking into account the current national and international scenarios of nuclear energy. (author)

  2. Public meetings on nuclear waste management: their function and organization

    Energy Technology Data Exchange (ETDEWEB)

    Duvernoy, E.G.; Marcus, A.A.; Overcast, T.; Schilling, A.H.

    1981-05-01

    This report focuses on public meetings as a vehicle for public participation in nuclear waste management. The nature of public meetings is reviewed and the functions served by meetings highlighted. The range of participants and their concerns are addressed, including a review of the participants from past nuclear waste management meetings. A sound understanding of the expected participants allows DOE to tailor elements of the meeting, such as notification, format, and agenda to accommodate the attendees. Finally, the report discusses the organization of public meetings on nuclear waste management in order to enhance the DOE's functions for such meetings. Possible structures are suggested for a variety of elements that are relevant prior to, during and after the public meeting. These suggestions are intended to supplement the DOE Public Participation Manual.

  3. Public meetings on nuclear waste management: their function and organization

    International Nuclear Information System (INIS)

    Duvernoy, E.G.; Marcus, A.A.; Overcast, T.; Schilling, A.H.

    1981-05-01

    This report focuses on public meetings as a vehicle for public participation in nuclear waste management. The nature of public meetings is reviewed and the functions served by meetings highlighted. The range of participants and their concerns are addressed, including a review of the participants from past nuclear waste management meetings. A sound understanding of the expected participants allows DOE to tailor elements of the meeting, such as notification, format, and agenda to accommodate the attendees. Finally, the report discusses the organization of public meetings on nuclear waste management in order to enhance the DOE's functions for such meetings. Possible structures are suggested for a variety of elements that are relevant prior to, during and after the public meeting. These suggestions are intended to supplement the DOE Public Participation Manual

  4. Organizing the Canadian nuclear industry to meet the challenge

    International Nuclear Information System (INIS)

    Lortie, Pierre.

    1983-06-01

    The CANDU reactor is struggling for a share of the dwindling reactor market against formidable and well-established competition. The Canadian nuclear industry has historically depended upon two crown corporations, Atomic Energy of Canada Ltd. and Ontario Hydro, which have taken the lead in designing and engineering the reactor. Crown corporations are not notably successful in marketing, however, and the time has come for the industry to organize itself in preparation for an aggressive export drive

  5. Quantification of the spatial organization of the nuclear lamina as a tool for cell classification

    NARCIS (Netherlands)

    Righolt, C.H.; Zatreanu, D.A.; Raz, V.

    2013-01-01

    The nuclear lamina is the structural scaffold of the nuclear envelope that plays multiple regulatory roles in chromatin organization and gene expression as well as a structural role in nuclear stability. The lamina proteins, also referred to as lamins, determine nuclear lamina organization and

  6. Workshop Summary for Maintaining Innovation and Security in Biotechnology: Lessons Learned from Nuclear, Chemical, and Informational Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Althouse, Paris [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-10-11

    In the fast-paced field of biotechnology where innovation has such far-reaching impacts on human health and the environment, dealing with the implications of possible illicit activities, accidents or unintended research consequences with potential detrimental societal impacts tends to remain in the background. While controls may be inevitable for the biotech industry, workshop attendees agreed that the way in which controls are implemented will play a major role in the agility and innovation of the biotechnology industry. There is little desire to slow down the pace of the gains while dealing with the security issues that arise. As was seen from the brief examinations of the Nuclear, Chemical, and Information Technology sectors explored in this workshop, establishing a regulatory regime needs to be a partnership between the public, corporate interests, scientists, and the government. Regulation is often written to combat perceived risk rather than actual risk—the public’s perceptions (occasionally even fictional portrayals) can spur regulatory efforts. This leads to the need for a thorough and continuing assessment of the risks posed by modern biotechnology. Inadequate or minimal risk assessment might expedite development in the short term but has potential negative long-term security and economic consequences. Industry and the technical community also often have a large role in setting regulatory policy, especially when well-crafted incentives are incorporated into the regulations. Such incentives might actually lead to enhanced innovation while poorly designed incentives can actually reduce safety and security. Any regulations should be as agile and flexible as the technology they regulate and when applied to biotechnologies they will need a new framework for thinking and implementing. The new framework should consider biotechnology as a technology and not simply a science since it is an extremely complex and adaptive system. This suggests the need to invest

  7. Dynamic Length Changes of Telomeres and Their Nuclear Organization in Chronic Myeloid Leukemia

    International Nuclear Information System (INIS)

    Samassekou, Oumar

    2013-01-01

    Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the t(9;22) translocation. As in most cancers, short telomeres are one of the features of CML cells, and telomere shortening accentuates as the disease progresses from the chronic phase to the blastic phase. Although most individual telomeres are short, some of them are lengthened, and long individual telomeres occur non-randomly and might be associated with clonal selection. Telomerase is the main mechanism used to maintain telomere lengths, and its activity increases when CML evolves toward advanced stages. ALT might be another mechanism employed by CML cells to sustain the homeostasis of their telomere lengths and this mechanism seems predominant at the early stage of leukemogenesis. Also, telomerase and ALT might jointly act to maintain telomere lengths at the chronic phase, and as CML progresses, telomerase becomes the major mechanism. Finally, CML cells display an altered nuclear organization of their telomeres which is characterized by the presence of high number of telomeric aggregates, a feature of genomic instability, and differential positioning of telomeres. CML represents a good model to study mechanisms responsible for dynamic changes of individual telomere lengths and the remodeling of telomeric nuclear organization throughout cancer progression

  8. Dynamic Length Changes of Telomeres and Their Nuclear Organization in Chronic Myeloid Leukemia

    Energy Technology Data Exchange (ETDEWEB)

    Samassekou, Oumar [Manitoba Institute of Cell Biology, Cancer Care Manitoba, Department of Physiology, University of Manitoba, Winnipeg, Manitoba R3E 0V9 (Canada)

    2013-08-22

    Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the t(9;22) translocation. As in most cancers, short telomeres are one of the features of CML cells, and telomere shortening accentuates as the disease progresses from the chronic phase to the blastic phase. Although most individual telomeres are short, some of them are lengthened, and long individual telomeres occur non-randomly and might be associated with clonal selection. Telomerase is the main mechanism used to maintain telomere lengths, and its activity increases when CML evolves toward advanced stages. ALT might be another mechanism employed by CML cells to sustain the homeostasis of their telomere lengths and this mechanism seems predominant at the early stage of leukemogenesis. Also, telomerase and ALT might jointly act to maintain telomere lengths at the chronic phase, and as CML progresses, telomerase becomes the major mechanism. Finally, CML cells display an altered nuclear organization of their telomeres which is characterized by the presence of high number of telomeric aggregates, a feature of genomic instability, and differential positioning of telomeres. CML represents a good model to study mechanisms responsible for dynamic changes of individual telomere lengths and the remodeling of telomeric nuclear organization throughout cancer progression.

  9. The epigenetics of nuclear envelope organization and disease

    International Nuclear Information System (INIS)

    Schirmer, Eric C.

    2008-01-01

    Mammalian chromosomes and some specific genes have non-random positions within the nucleus that are tissue-specific and heritable. Work in many organisms has shown that genes at the nuclear periphery tend to be inactive and altering their partitioning to the interior results in their activation. Proteins of the nuclear envelope can recruit chromatin with specific epigenetic marks and can also recruit silencing factors that add new epigenetic modifications to chromatin sequestered at the periphery. Together these findings indicate that the nuclear envelope is a significant epigenetic regulator. The importance of this function is emphasized by observations of aberrant distribution of peripheral heterochromatin in several human diseases linked to mutations in NE proteins. These debilitating inherited diseases range from muscular dystrophies to the premature aging progeroid syndromes and the heterochromatin changes are just one early clue for understanding the molecular details of how they work. The architecture of the nuclear envelope provides a unique environment for epigenetic regulation and as such a great deal of research will be required before we can ascertain the full range of its contributions to epigenetics

  10. The epigenetics of nuclear envelope organization and disease

    Energy Technology Data Exchange (ETDEWEB)

    Schirmer, Eric C. [Wellcome Trust Centre for Cell Biology, University of Edinburgh, Kings Buildings, Michael Swann Building, Room 5.22, Edinburgh EH9 3JR (United Kingdom)], E-mail: e.schirmer@ed.ac.uk

    2008-12-01

    Mammalian chromosomes and some specific genes have non-random positions within the nucleus that are tissue-specific and heritable. Work in many organisms has shown that genes at the nuclear periphery tend to be inactive and altering their partitioning to the interior results in their activation. Proteins of the nuclear envelope can recruit chromatin with specific epigenetic marks and can also recruit silencing factors that add new epigenetic modifications to chromatin sequestered at the periphery. Together these findings indicate that the nuclear envelope is a significant epigenetic regulator. The importance of this function is emphasized by observations of aberrant distribution of peripheral heterochromatin in several human diseases linked to mutations in NE proteins. These debilitating inherited diseases range from muscular dystrophies to the premature aging progeroid syndromes and the heterochromatin changes are just one early clue for understanding the molecular details of how they work. The architecture of the nuclear envelope provides a unique environment for epigenetic regulation and as such a great deal of research will be required before we can ascertain the full range of its contributions to epigenetics.

  11. Continuous polo-like kinase 1 activity regulates diffusion to maintain centrosome self-organization during mitosis.

    Science.gov (United States)

    Mahen, Robert; Jeyasekharan, Anand D; Barry, Nicholas P; Venkitaraman, Ashok R

    2011-05-31

    Whether mitotic structures like the centrosome can self-organize from the regulated mobility of their dynamic protein components remains unclear. Here, we combine fluorescence spectroscopy and chemical genetics to study in living cells the diffusion of polo-like kinase 1 (PLK1), an enzyme critical for centrosome maturation at the onset of mitosis. The cytoplasmic diffusion of a functional EGFP-PLK1 fusion correlates inversely with known changes in its enzymatic activity during the cell cycle. Specific EGFP-PLK1 inhibition using chemical genetics enhances mobility, as do point mutations inactivating the polo-box or kinase domains responsible for substrate recognition and catalysis. Spatial mapping of EGFP-PLK1 diffusion across living cells, using raster image correlation spectroscopy and line scanning, detects regions of low mobility in centrosomes. These regions exhibit characteristics of increased transient recursive EGFP-PLK1 binding, distinct from the diffusion of stable EGFP-PLK1-containing complexes in the cytoplasm. Chemical genetic suppression of mitotic EGFP-PLK1 activity, even after centrosome maturation, causes defects in centrosome structure, which recover when activity is restored. Our findings imply that continuous PLK1 activity during mitosis maintains centrosome self-organization by a mechanism dependent on its reaction and diffusion, suggesting a model for the formation of stable mitotic structures using dynamic protein kinases.

  12. Continuous polo-like kinase 1 activity regulates diffusion to maintain centrosome self-organization during mitosis

    Science.gov (United States)

    Mahen, Robert; Jeyasekharan, Anand D.; Barry, Nicholas P.; Venkitaraman, Ashok R.

    2011-01-01

    Whether mitotic structures like the centrosome can self-organize from the regulated mobility of their dynamic protein components remains unclear. Here, we combine fluorescence spectroscopy and chemical genetics to study in living cells the diffusion of polo-like kinase 1 (PLK1), an enzyme critical for centrosome maturation at the onset of mitosis. The cytoplasmic diffusion of a functional EGFP-PLK1 fusion correlates inversely with known changes in its enzymatic activity during the cell cycle. Specific EGFP-PLK1 inhibition using chemical genetics enhances mobility, as do point mutations inactivating the polo-box or kinase domains responsible for substrate recognition and catalysis. Spatial mapping of EGFP-PLK1 diffusion across living cells, using raster image correlation spectroscopy and line scanning, detects regions of low mobility in centrosomes. These regions exhibit characteristics of increased transient recursive EGFP-PLK1 binding, distinct from the diffusion of stable EGFP-PLK1–containing complexes in the cytoplasm. Chemical genetic suppression of mitotic EGFP-PLK1 activity, even after centrosome maturation, causes defects in centrosome structure, which recover when activity is restored. Our findings imply that continuous PLK1 activity during mitosis maintains centrosome self-organization by a mechanism dependent on its reaction and diffusion, suggesting a model for the formation of stable mitotic structures using dynamic protein kinases. PMID:21576470

  13. Effectiveness of the GAEC standard of cross compliance Crop rotations in maintaining organic matter levels in soils

    Directory of Open Access Journals (Sweden)

    Lamberto Borrelli

    2011-08-01

    Full Text Available Our study was conducted in the framework of EFFICOND project, with the aim of evaluating the environmental effectiveness of GAEC (Good Agricultural and Environmental Conditions standards with particular focus to the maintenance of soil organic matter (SOM levels through the appropriate crop rotation. The study analyzed the effect of crop rotation on the build-up of soil organic matter in three different areas of Italy, located in the North (Lodi, Centre (Fagna, Firenze and South (Foggia of Italy, characterized by different climate, soil, and cropping systems. In the two experiments conducted in the South of Italy, in a dry Mediterranean climate, the stock of C was kept steady in most of the rotations compared with the monoculture of durum wheat. In such environment, with very dry and hot summers, introducing a year of fallow seems to improve SOM content, but these data need further investigation. In the Centre of Italy (Fagna, with less extreme climate than in Foggia, the effect of rotation compared to the monoculture of maize is negligible, but investigation on the soil organic matter composition, showed that in the rotation the SOM appeared to be more stable and, in the long term, probably more resistant to degradation. Eventually, experiments conducted in the North of Italy, showed that the monoculture, despite the application of FYM (Farm Yard Manure or semi-liquid manure, led to a decrease of SOM. To an increase of the rotation complexity, corresponded an increase in the stock of C in soil. Summarizing, results showed that crop rotation could guarantee the maintenance of SOM level, given that the input of C to the soil is maintained at a good level or, in other word, that productivity of the system is high. Other practices such as conservation tillage, appropriate management of residues, and manure application could enhance the positive effect of rotations. Moreover, preliminary investigation of soil microbial diversity, suggests the

  14. Organization and management for decommissioning of large nuclear facilities

    International Nuclear Information System (INIS)

    2000-01-01

    For nuclear facilities, decommissioning is the final phase in the life-cycle after siting, design, construction, commissioning and operation. It is a complex process involving operations such as detailed surveys, decontamination and dismantling of plant equipment and facilities, demolition of buildings and structures, and management of resulting waste and other materials, whilst taking into account aspects of health and safety of the operating personnel and the general public, and protection of the environment. Careful planning and management is essential to ensure that decommissioning is accomplished in a safe and cost effective manner. Guidance on organizational aspects may lead to better decision making, reductions in time and resources, lower doses to the workers and reduced impact on public health and the environment. The objective of this report is to provide information and guidance on the organization and management aspects for the decommissioning of large nuclear facilities which will be useful for licensees responsible for discharging these responsibilities. The information contained in the report may also be useful to policy makers, regulatory bodies and other organizations interested in the planning and management of decommissioning. In this report, the term 'decommissioning' refers to those actions that are taken at the end of the useful life of a nuclear facility in withdrawing it from service with adequate regard for the health and safety of workers and members of the public and for the protection of the environment. The term 'large nuclear facilities' involves nuclear power plants, large nuclear research reactors and other fuel cycle facilities such as reprocessing plants, fuel conversion, fabrication and enrichment plants, as well as spent fuel storage and waste management plants. Information on the planning and management for decommissioning of smaller research reactors or other small nuclear facilities can be found elsewhere. The report covers

  15. Evaluating safety-critical organizations - emphasis on the nuclear industry

    International Nuclear Information System (INIS)

    Reiman, Teemu; Oedewald, Pia

    2009-04-01

    An organizational evaluation plays a key role in the monitoring, as well as controlling and steering, of the organizational safety culture. If left unattended, organizations have a tendency to gradually drift into a condition where they have trouble identifying their vulnerabilities and mechanisms or practices that create or maintain these vulnerabilities. The aim of an organizational evaluation should be to promote increased understanding of the sociotechnical system and its changing vulnerabilities. Evaluation contributes to organizational development and management. Evaluations are used in various situations, but when the aim is to learn about possible new vulnerabilities, identify organizational reasons for problems, or prepare for future challenges, the organization is most open to genuine surprises and new findings. It is recommended that organizational evaluations should be conducted when - there are changes in the organizational structures - new tools are implemented - when the people report increased workplace stress or a decreased working climate - when incidents and near-misses increase - when work starts to become routine - when weak signals (such as employees voicing safety concerns or other worries, the organization 'feels' different, organizational climate has changed) are perceived. In organizations that already have a high safety level, safety managers work for their successors. This means that they seldom see the results of their successful efforts to improve safety. This is due to the fact that it takes time for the improvement to become noticeable in terms of increased measurable safety levels. The most challenging issue in an organizational evaluation is the definition of criteria for safety. We have adopted a system safety perspective and we state that an organization has a high potential for safety when - safety is genuinely valued and the members of the organization are motivated to put effort on achieving high levels of safety - it is

  16. Evaluating safety-critical organizations - emphasis on the nuclear industry

    Energy Technology Data Exchange (ETDEWEB)

    Reiman, Teemu; Oedewald, Pia (VTT, Technical Research Centre of Finland (Finland))

    2009-04-15

    An organizational evaluation plays a key role in the monitoring, as well as controlling and steering, of the organizational safety culture. If left unattended, organizations have a tendency to gradually drift into a condition where they have trouble identifying their vulnerabilities and mechanisms or practices that create or maintain these vulnerabilities. The aim of an organizational evaluation should be to promote increased understanding of the sociotechnical system and its changing vulnerabilities. Evaluation contributes to organizational development and management. Evaluations are used in various situations, but when the aim is to learn about possible new vulnerabilities, identify organizational reasons for problems, or prepare for future challenges, the organization is most open to genuine surprises and new findings. It is recommended that organizational evaluations should be conducted when - there are changes in the organizational structures - new tools are implemented - when the people report increased workplace stress or a decreased working climate - when incidents and near-misses increase - when work starts to become routine - when weak signals (such as employees voicing safety concerns or other worries, the organization 'feels' different, organizational climate has changed) are perceived. In organizations that already have a high safety level, safety managers work for their successors. This means that they seldom see the results of their successful efforts to improve safety. This is due to the fact that it takes time for the improvement to become noticeable in terms of increased measurable safety levels. The most challenging issue in an organizational evaluation is the definition of criteria for safety. We have adopted a system safety perspective and we state that an organization has a high potential for safety when - safety is genuinely valued and the members of the organization are motivated to put effort on achieving high levels of safety

  17. Radiation effects on organic materials in nuclear plants. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Bruce, M B; Davis, M V

    1981-11-01

    A literature search was conducted to identify information useful in determining the lowest level at which radiation causes damage to nuclear plant equipment. Information was sought concerning synergistic effects of radiation and other environmental stresses. Organic polymers are often identified as the weak elements in equipment. Data on radiation effects are summarized for 50 generic name plastics and 16 elastomers. Coatings, lubricants, and adhesives are treated as separate groups. Inorganics and metallics are considered briefly. With a few noted exceptions, these are more radiation resistant than organic materials. Some semiconductor devices and electronic assemblies are extremely sensitive to radiation. Any damage threshold including these would be too low to be of practical value. With that exception, equipment exposed to less than 10/sup 4/ rads should not be significantly affected. Equipment containing no Teflon should not be significantly affected by 10/sup 5/ rads. Data concerning synergistic effects and radiation sensitization are discussed. The authors suggest correlations between the two effects.

  18. Radiation effects on organic materials in nuclear plants. Final report

    International Nuclear Information System (INIS)

    Bruce, M.B.; Davis, M.V.

    1981-11-01

    A literature search was conducted to identify information useful in determining the lowest level at which radiation causes damage to nuclear plant equipment. Information was sought concerning synergistic effects of radiation and other environmental stresses. Organic polymers are often identified as the weak elements in equipment. Data on radiation effects are summarized for 50 generic name plastics and 16 elastomers. Coatings, lubricants, and adhesives are treated as separate groups. Inorganics and metallics are considered briefly. With a few noted exceptions, these are more radiation resistant than organic materials. Some semiconductor devices and electronic assemblies are extremely sensitive to radiation. Any damage threshold including these would be too low to be of practical value. With that exception, equipment exposed to less than 10 4 rads should not be significantly affected. Equipment containing no Teflon should not be significantly affected by 10 5 rads. Data concerning synergistic effects and radiation sensitization are discussed. The authors suggest correlations between the two effects

  19. Maintaining health sector collaborations between United States non-governmental organizations and North Korea through innovation and planning.

    Science.gov (United States)

    Yim, Eugene S; Choi, Ricky Y; VanRooyen, Michael

    2009-01-01

    Humanitarian agencies in North Korea operate within a complex sociopolitical environment historically characterized by a baseline of mistrust. As a result of operating within such a heated environment, health sector collaborations between such agencies and the North Korean government have followed unpredictable courses. The factors that have contributed to successful programmatic collaborations, as perceived by United States non-governmental organizations (NGOs) and North Korean officials were investigated. A qualitative, multi-case, comparative, research design using semistructured interviews was used. Expert North Korean informants were interviewed to generate a list of factors contributing to programmatic success, defined as fulfilling mutually established objectives through collaboration. The North Korean informants were asked to identify US NGOs that fulfill these criteria ("mission-compatible NGOs"). Representatives from all of the mission compatible NGOs were interviewed. All informants provided their perspectives on the factors that contributed to successful programmatic collaborations. The interviews were recorded, transcribed, and analyzed for thematic content. North Korean informants identified six mission-compatible US NGOs. The North Korean and US NGO informants provided a number of factors that contributed to successful programs. These factors were grouped into the following themes: (1) responsiveness to North Korean requests; (2) resident status; (3) program monitoring; (4) sincerity (apolitical objectives); (5) information gathering; and (6) interagency collaboration. Some US NGOs have devised innovative measures to work within a unique set of parameters in North Korea. Both US NGOs and North Korean authorities have made significant concessions to maintain their programmatic partnerships. In this manner, seasoned collaborators have employed creative strategies and a form of health diplomacy to facilitate programmatic success in North Korea by

  20. Nuclear organizations in France - USA - Japan; Organisations nucleaires France - USA- Japon

    Energy Technology Data Exchange (ETDEWEB)

    David, J.L.

    1996-10-01

    After an history of the nuclear events of the post-war period in the world, the nuclear organization in three different countries is developed. First, the case of France is described with a chronological account of events, as well as the intern and international laws. Then, the importance of nuclear energy in the electricity production in the USA is put forward. Finally, the nuclear organization in Japan is presented in the same way. (TEC). 4 figs., 1 tab.

  1. Framework of orientation for the discussion of measures required to maintain and further the expert knowledge and qualification of nuclear power plant managers and supervisors

    International Nuclear Information System (INIS)

    Farber, G.

    1984-01-01

    This report is focussed on the important aspects of the training and retraining of nuclear power plant managers and supervisors. The functional levels of the onsite operating organization of nine nuclear power plants are described and analyzed in order to determine the comparability of management positions as well as the responsibilities of the job incumbents. Retraining requirements are suggested depending on position, responsibilities, and relevance to safety. The manager's role in case of emergencies leads to specific demands with regard to regular training to cope with inadequate core cooling and to mitigate accidents. (orig.) [de

  2. Iodine-129 in aquatic organisms near nuclear fuels processing plants

    International Nuclear Information System (INIS)

    Watson, D.G.

    1975-04-01

    Concentrations of 129 I in two aquatic habitats near nuclear fuel processing plants were highest in algae and crustaceans. These two forms may be useful in future monitoring of 129 I. There is some indication of an increase in atom ratios and specific activity in aquatic organisms over that in water and sediments. Additional measurements should be made to verify this conclusion. Efforts should continue to measure the possible long term build-up of 129 I in aquatic environments receiving effluents from fuels reprocessing plants. Even at very low rates of release to the environment, the long physical half-life of 129 I creates the potential for build-up of this nuclide to significant levels. (U.S.)

  3. A study on the monitoring of the success path performance for maintaining critical safety function in nuclear power plant

    International Nuclear Information System (INIS)

    Kang, S. K.; Sin, Y. C.

    2002-01-01

    In this paper, we analyzed and suggested the period and the criteria of the evaluation about the performance of the success path system for maintaining critical safety function for CFM/SPM design. Each system of the success path peculiarly needs to have different evaluation period for checking the performance of the success path according to the original function of the success path system, also, we reviewed the needs of evaluation about the performance of the success path in the course of both emergency operation and normal operation. We practically reviewed and analyzed the start time of performance evaluation and evaluation criteria based on the YGN 3 and 4 RAT, EOP and FRP. Also, we reviewed the evaluation criteria of the performance for success path system through the experience of the plant operation

  4. Challenges for Nuclear Energy Agencies: Maintaining Orthodoxy or Learning from the Most Admired Knowledge Enterprises in the World

    International Nuclear Information System (INIS)

    Jashapara, A.

    2016-01-01

    Full text: Governments recognize that their economic productivity and growth is driven by knowledge, technology and learning; namely the knowledge economy. There are no blueprints on how to best to manage knowledge enterprises and knowledge workers in this new context. This paper examines the knowledge management practices of some international firms to assess how they manage their intangible assets. The firms chosen have all won the Most Admired Knowledge Enterprises (MAKE) awards. They include Ernst&Young (US), Toyota (Japan), World Bank, Infosys (India), Unilever (UK/Netherlands), Honda (Japan), Royal Dutch Shell (UK/Netherlands) and Tata Consultancy Services (India). The focus of the paper is on the practices and real issues encountered by these firms rather than whether they support or challenge current knowledge management theory or orthodoxy. The paper concludes by exploring key lessons learned by these firms and their application to challenges among nuclear energy agencies. (author

  5. Joint submission of the Canadian Nuclear Association and the Organization of CANDU Industries to the Ontario Nuclear Safety Review

    International Nuclear Information System (INIS)

    1987-08-01

    The manufacturing company members of the Canadian Nuclear Association and the Organization of CANDU Industries are proud to have played their part in the development of the peaceful application of nuclear technology in Ontario, and the achievement of the very real benefits discussed in this paper, which greatly outweigh the hypothetical risks

  6. Organization and management activities in the nuclear power industry

    International Nuclear Information System (INIS)

    Evans, R.C.; Whitesel, R.N.

    1994-01-01

    The purpose of organization and management development activities in the commercial nuclear power industry is to foster high levels of power plant performance and safety through improved human performance. The NRC has been working to develop assessment tools to assay the effects of organizational factors on plant safety. The utility industry has been working on initiatives targeting individual accountability, the improvement of plant performance and the elimination of the items identified through the NRC assessment process. Organization and management activities do not focus on industry organizational charts, but on the personnel processes and dimensions (factors) that affect safety and economic performance. As individual terms these activities are often combined and referred to as organizational factors. As an area of study, organizational factors has become more prominent as the industry emphasis has switched in recent years from hardware issues related to safety and economics, to personnel-related issues. Beyond the obvious safety objectives affected by improved human performance, plant performance improvements, in areas such as capacity factors, can be achieved through improved human performance. For example, it is estimated that as many as half of the unplanned reactor scrams are caused by personnel errors. The integrated effect of these scram-initiating errors is conservatively estimated to be 100 lost capacity days per year. The financial impact of these events is estimated to be $100M per year

  7. Executive summary of the guidebook on training to establish and maintain the qualification and competence of nuclear power plant operations personnel

    International Nuclear Information System (INIS)

    1989-01-01

    Since the IAEA published its Guidebook on the Qualification of Nuclear Power Plant Operations Personnel in 1984 (Technical Reports Series No. 242) there have been important developments in the approach for training adopted by many operating organizations in different countries. The Guidebook, described in this report, proposes an approach which is comprehensive and systematic in its methodology and cost effective in its implementation. 5 refs, 1 fig

  8. An evolutionarily conserved phosphatidate phosphatase maintains lipid droplet number and endoplasmic reticulum morphology but not nuclear morphology

    Directory of Open Access Journals (Sweden)

    Anoop Narayana Pillai

    2017-11-01

    Full Text Available Phosphatidic acid phosphatases are involved in the biosynthesis of phospholipids and triacylglycerol, and also act as transcriptional regulators. Studies to ascertain their role in lipid metabolism and membrane biogenesis are restricted to Opisthokonta and Archaeplastida. Here, we report the role of phosphatidate phosphatase (PAH in Tetrahymena thermophila, belonging to the Alveolata clade. We identified two PAH homologs in Tetrahymena, TtPAH1 and TtPAH2. Loss of function of TtPAH1 results in reduced lipid droplet number and an increase in endoplasmic reticulum (ER content. It also results in more ER sheet structure as compared to wild-type Tetrahymena. Surprisingly, we did not observe a visible defect in the nuclear morphology of the ΔTtpah1 mutant. TtPAH1 rescued all known defects in the yeast pah1Δ strain and is conserved functionally between Tetrahymena and yeast. The homologous gene derived from Trypanosoma also rescued the defects of the yeast pah1Δ strain. Our results indicate that PAH, previously known to be conserved among Opisthokonts, is also present in a set of distant lineages. Thus, a phosphatase cascade is evolutionarily conserved and is functionally interchangeable across eukaryotic lineages.

  9. Discussion on organization structure system of nuclear power projects in China

    International Nuclear Information System (INIS)

    Wang Zhi

    2011-01-01

    With the development of the nuclear power industry in China, several AE companies were born and now play a major role in building nuclear power projects in China and overseas. After studying current organization structure systems of all nuclear power AE companies in China and comparing with successful foreign ones, this paper proposes some approaches to optimize the structure. (author)

  10. Best practices in the organization, management and conduct of an effective investigation of events at nuclear power plants

    International Nuclear Information System (INIS)

    2008-09-01

    IAEA Safety Standards Series No. SF-1 entitled Fundamental Safety Principles: Safety Fundamentals states the need for operating organizations to establish a programme for the feedback and analysis of operating experience in nuclear power plants. Such a programme ensures that operating experience is analysed, events important to safety are reviewed in depth, lessons learned are disseminated to the staff of the organization and to the relevant national and international organizations, and corrective actions are effectively implemented. This publication has been developed to provide advice and assistance to nuclear installations, and related institutions including contractors and support organizations to strengthen and enhance their own feedback process through the implementation of best practices in organization, management and conduct of an effective investigation of events. Conducting an effective investigation of events is essential in supporting a proactive safety management approach of preventing events from occurring. Event investigation is the heart of the operating experience feedback programme and in an operating organization it is essential to develop and maintain necessary expertise in this area. Experience has shown that it is not sufficient to identify only the direct causes of an event and the event is bound to recur unless all the root causes and casual factors for an event are identified and necessary corrective actions are developed and implemented. The present publication is the outcome of a coordinated effort involving the participation of experts of nuclear organizations in several Member States. It was developed to further elaborate on how to implement the event investigation requirements in the area of feedback of operating experience, as specified in the IAEA Safety Requirements publication NS-R-2 on Safety of Nuclear Power Plants: Operation. This document will also complement the publication IAEA Services Series No. 10 - PROSPER Guidelines

  11. Principal organic materials in a repository for spent nuclear fuel

    International Nuclear Information System (INIS)

    Hallbeck, Lotta

    2010-01-01

    The largest pool of organic material in a repository at closure is the organic material in the bentonite in buffer and backfill. It is impossible to make any assumptions as to how much of this material will be available for biodegradation, since the character of the material is unknown. However, it is unlikely that this organic material can dissolve in groundwater unless the bentonite loses its swelling capacity. The second largest pool will be the biofilms formed on the rock surfaces. This assumption presupposes that no cleaning is undertaken before repository closure. The third largest pool is the organic material produced by microorganisms using hydrogen from the anaerobic corrosion of iron in steel as an energy source. The following provides summary descriptions of the different pools of organic material that will remain in the repository: 1. Microorganisms. Their effect would mainly be to reduce the redox potential soon after repository closure. They may contribute to the depletion of the oxygen entrapped during repository construction, an effect that would not jeopardise repository stability. If the dominant microorganisms in the anaerobic environment are sulphate-reducing bacteria, oxidation of organic material would lead to the formation of HS - . The produced sulphide could corrode the copper canisters under anaerobic conditions if it reaches them. Another effect of microorganisms would be to increase the complexing capacity of the groundwater due to excreted metabolites. The impact of these compounds is not yet clear, although it will surely not be very important, due to the small amounts of such substances. 2. Materials in the ventilation air. Their effect will probably be to help maintain reducing conditions in the area, although this effect will likely be minimal or negligible. 3. Construction materials. Among these materials, we emphasise the organic materials present in concrete, asphalt, bentonite, and wood. Hydrocarbons from asphalt may help reduce

  12. Principal organic materials in a repository for spent nuclear fuel

    Energy Technology Data Exchange (ETDEWEB)

    Hallbeck, Lotta (Microbial Analytics Sweden AB, Moelnlycke (Sweden))

    2010-01-15

    The largest pool of organic material in a repository at closure is the organic material in the bentonite in buffer and backfill. It is impossible to make any assumptions as to how much of this material will be available for biodegradation, since the character of the material is unknown. However, it is unlikely that this organic material can dissolve in groundwater unless the bentonite loses its swelling capacity. The second largest pool will be the biofilms formed on the rock surfaces. This assumption presupposes that no cleaning is undertaken before repository closure. The third largest pool is the organic material produced by microorganisms using hydrogen from the anaerobic corrosion of iron in steel as an energy source. The following provides summary descriptions of the different pools of organic material that will remain in the repository: 1. Microorganisms. Their effect would mainly be to reduce the redox potential soon after repository closure. They may contribute to the depletion of the oxygen entrapped during repository construction, an effect that would not jeopardise repository stability. If the dominant microorganisms in the anaerobic environment are sulphate-reducing bacteria, oxidation of organic material would lead to the formation of HS-. The produced sulphide could corrode the copper canisters under anaerobic conditions if it reaches them. Another effect of microorganisms would be to increase the complexing capacity of the groundwater due to excreted metabolites. The impact of these compounds is not yet clear, although it will surely not be very important, due to the small amounts of such substances. 2. Materials in the ventilation air. Their effect will probably be to help maintain reducing conditions in the area, although this effect will likely be minimal or negligible. 3. Construction materials. Among these materials, we emphasise the organic materials present in concrete, asphalt, bentonite, and wood. Hydrocarbons from asphalt may help reduce

  13. Nuclear-related training and education offered by nonacademic organizations (preliminary)

    International Nuclear Information System (INIS)

    Howard, L.

    1981-11-01

    The results of a survey of nuclear-related training and education provided by nonacademic training organizations are presented in this report. The survey instrument was distributed by the Institute of Nuclear Power Operations to 136 training organizations. The scope of the survey was not intended to be comprehensive, but rather to include the primary sources of nonacademic nuclear-related training and education offered to utility personnel. The survey universe was compiled from training organizations listed in the 1981 Nuclear News Buyer's Guide. Forty-three percent of the survey population (59 organizations) responded to the questionnaire of which 31 percent (42) reported they offered nuclear-related training programs and 12 percent (17) reported they did not offer any nuclear-related training

  14. Peculiarities of organizing the construction of nuclear medicine facilities and the transportation of radionuclide

    Science.gov (United States)

    Telichenko, Valeriy; Malykha, Galina; Dorogan, Igor

    2017-10-01

    The article is devoted to the organization of construction of nuclear medicine facilities in Russia. The article describes the main methods of nuclear medical diagnostics, as well as the peculiarities of nuclear medicine facilities that determine the need for application of specific methods for organizing and managing the construction, methods of requirements management in the organization of construction of nuclear medicine facilities. Sustainable development of the transport of radioactive isotopes from the place of production to places of consumption is very important for the safety of the population. The requirements management system is an important and necessary component in organizing the construction of complex facilities, such as nuclear medicine facilities. The author developed and proposed a requirements management system for the design, construction and operation of a nuclear medicine facility, which provides for a cyclic sequence of actions. This system allows reducing the consumption of resources including material and energy during construction and operation of complex objects.

  15. A Guidebook for Evaluating Organizations in the Nuclear Industry - an example of safety culture evaluation

    International Nuclear Information System (INIS)

    Oedewald, Pia; Pietikaeinen, Elina; Reiman, Teemu

    2011-06-01

    Organizations in the nuclear industry need to maintain an overview on their vulnerabilities and strengths with respect to safety. Systematic periodical self assessments are necessary to achieve this overview. This guidebook provides suggestions and examples to assist power companies but also external evaluators and regulators in carrying out organizational evaluations. Organizational evaluation process is divided into five main steps. These are: 1) planning the evaluation framework and the practicalities of the evaluation process, 2) selecting data collection methods and conducting the data acquisition, 3) structuring and analysing the data, 4) interpreting the findings and 5) reporting the evaluation results with possible recommendations. The guidebook emphasises the importance of a solid background framework when dealing with multifaceted phenomena like organisational activities and system safety. The validity and credibility of the evaluation stem largely from the evaluation team's ability to crystallize what they mean by organization and safety when they conduct organisational safety evaluations - and thus, what are the criteria for the evaluation. Another important and often under-considered phase in organizational evaluation is interpretation of the findings. In this guidebook a safety culture evaluation in a Nordic nuclear power plant is presented as an example of organizational evaluation. With the help of the example, challenges of each step in the organizational evaluation process are described. Suggestions for dealing with them are presented. In the case example, the DISC (Design for Integrated Safety culture) model is used as the evaluation framework. The DISC model describes the criteria for a good safety culture and the organizational functions necessary to develop a good safety culture in the organization

  16. Organization of nuclear safety and radiation protection in Switzerland

    International Nuclear Information System (INIS)

    Pretre, S.

    1995-01-01

    In Switzerland an important distinction is made between radiation protection (in charge of the use of ionizing radiations for medical uses or non nuclear industry), and nuclear safety (in charge of nuclear industry, including prevention or limitation of any risk of nuclear accident). In the eighties, it has been decided to make two laws for these two topics. The law for radioprotection, voted in 1991 is enforced since 1994 by OFSP (Office Federal de la Sante Publique). It performs any radiation monitoring outside nuclear industry plants. The law for nuclear safety, that should be enforced by OFEN (Office Federal de l'ENergie), is still not voted. The only existing legislation is the 1959 atomic law. (D.L.). 1 fig., 1 map

  17. Micro-organisms and nuclear waste: a neglected problem

    International Nuclear Information System (INIS)

    Arnott, Don.

    1989-01-01

    The paper addresses the problem of bacteria in nuclear waste disposal. A description is given of how bacteria colonised the Three Mile Island Nuclear Reactor soon after meltdown, demonstrating the ability of some bacteria to operate under extreme conditions. Work is also described indicating that microbial corrosion of metal canisters can occur. Thus the author recommends that studies of nuclear waste disposal should take into account the interrelations between geology, geochemistry and microbiology. (U.K.)

  18. Automatic Loading of Problems Using a Comorbidities Subset: One Step to Organize and Maintain the Patient's Problem List.

    Science.gov (United States)

    Márquez Fosser, Santiago; Gaiera, Alejandro; Otero, Carlos; Benitez, Sonia; Luna, Daniel; Quiroz, Fernán

    2017-01-01

    An accurate and updated problems' list is critical in a problem-oriented Electronic Health Record (EHR). The lack of organization and maintenance of the problems limits its value. Certain problems have a larger effect on the clinical evolution of the patient, these are known as Comorbidities. The aim of this paper is to evaluate the impact of the automatic loading of comorbidities in the organization and maintenance of inpatient problems' list using a comorbidities subset.

  19. Industrial organization. The government draws a new french nuclear landscape

    International Nuclear Information System (INIS)

    Foucher, N.

    2000-01-01

    This paper presents and explains the new nuclear industry. In order to rationalize Cogema and Framatome are going to be grouped in an holding called Topco with a nuclear pole and an electronic and new technologies pole. Framatome will be split in two parts and its connector technology subsidiary will be introduced on Change. (A.L.B.)

  20. Organization and staffing of the regulatory body for nuclear facilities. Safety guide

    International Nuclear Information System (INIS)

    2005-01-01

    The purpose of this safety guide is to provide recommendations for national authorities on the appropriate management system, organization and staffing for the regulatory body responsible for the regulation of nuclear facilities in order to achieve compliance with the applicable safety requirements. This safety guide covers the organization and staffing in relation to nuclear facilities such as: enrichment and fuel manufacturing plants. Nuclear power plants. Other reactors such as research reactors and critical assemblies. Spent fuel reprocessing plants. And radioactive waste management facilities such as treatment, storage and disposal facilities. This safety guide also covers issues related to the decommissioning of nuclear facilities, the closure of waste disposal facilities and site rehabilitation

  1. FAPIG's activities for public acceptance of nuclear energy. Analytical results of questionnaire executed at organized visits to nuclear power stations

    International Nuclear Information System (INIS)

    Mizoguchi, Tadao

    1999-01-01

    FAPIG organizes a visit to nuclear power station in every November. It is an object that visitors acquire the correct knowledge of nuclear power by looking at the various facilities in the nuclear power stations. The paper showed the analytical results of questionnaire executed at organized visits to the Kashiwazaki-Kariwa nuclear power station. The visitors were 18 women. The questionnaire was carried out by the same problems before and after seminar and a conducted tour. Their impressions and opinions and the changes are analyzed. The speakers used easy words, video, OHP, pamphlet and experimental equipment. These means showed very good results to visitors. The seminar had very large effect on just recognition of safety and need of it. The change of answer proved from 3 to 6 of need and from 0 to 7 of safety of it. Nine members indicated good understanding of seminar content. The interested items in the seminar were measurement of radiation, effects of radiation, reason of decreasing average life, Chernobyl accident, difference between nuclear power and atomic bomb and nuclear power dose not generate carbon dioxide and recycle plutonium after nuclear fission of uranium. (S.Y.)

  2. A review on the role of organic inputs in maintaining the soil carbon pool of the terrestrial ecosystem.

    Science.gov (United States)

    Bhattacharya, Satya Sundar; Kim, Ki-Hyun; Das, Subhasish; Uchimiya, Minori; Jeon, Byong Hun; Kwon, Eilhann; Szulejko, Jan E

    2016-02-01

    Among the numerous sources of greenhouse gases, emissions of CO2 are considerably affected by changes in the extent and type of land use, e.g., intensive agriculture, deforestation, urbanization, soil erosion, or wetland drainage. As a feasible option to control emissions from the terrestrial ecosystems, the scientific community has explored the possibility of enhancing soil carbon (C) storage capacity. Thus, restoration of damaged lands through conservation tillage, crop rotation, cover cropping, reforestation, sub-soiling of compacted lands, sustainable water management practices, and organic manuring are the major antidotes against attenuation of soil organic C (SOC) stocks. In this research, we focused on the effect of various man-made activities on soil biotic organics (e.g., green-, farm-yard manure, and composts) to understand how C fluxes from various sources contribute to the establishment of a new equilibrium in the terrestrial ecosystems. Although such inputs substitute a portion of chemical fertilizers, they all undergo activities that augment the rate and extent of decay to deplete the SOC bank. Here, we provide perspectives on the balancing factors that control the mineralization rate of organic matter. Our arguments are placed in the background of different land use types and their impacts on forests, agriculture, urbanization, soil erosion, and wetland destruction. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Elements of Organizational Culture Superintendents Perceive as Important to Create and Maintain a Successful Organization in Times of Crisis

    Science.gov (United States)

    Wilson, Marylou K.

    2012-01-01

    Purpose: The purpose of this study was to identify and describe the elements of culture public school superintendents perceive to be most important in creating and sustaining successful organizations in times of crisis. In addition, it was the purpose of this study to identify and describe the leadership strategies superintendents use to create…

  4. A concept map aiding the knowledge management to build the collective knowledge in a nuclear organization - a case study: IEN

    International Nuclear Information System (INIS)

    Cussa, Adriana L.D.; Fonseca, Marcus Vinicius de A.

    2009-01-01

    This paper's proposition is to build and apply a tool to aid the knowledge management based in the intellectual capital as a value and competitiveness aggregator for a science, technology and innovation public organization in the Brazilian's nuclear area - the 'Instituto de Engenharia Nuclear - IEN'. It will be presented the hole survey of the finalistic activities and what has been considered the intellectual capital to be developed and strategically validated in its decision making practices. It was also surveyed the inter relations between the stakeholders, hereby the maintainer (CNEN), federal government, support foundations, public employees and contributors, in many different aspects focusing the continuity of research and development (R and D) activities and its results. As it is going to be detailed, the tool has been designed based in the concept map methodology using the Cmap tools software. The hole cognitive basis used here was constructed under disclosed and recognized knowledge models about knowledge, knowledge management, knowledge transference and intellectual capital. (author)

  5. State of the art of nuclear facilities with organic cooled reactors

    International Nuclear Information System (INIS)

    Brede, O.

    1984-01-01

    USA, Canadian, and USSR activities aimed at developing nuclear facilities with organic cooled reactors are summarized. The facilities OMRE, PNPF, WR-1, and ARBUS are described, discussing in particular the problems of the chemistry of organic coolants. Finally, problems of further development and prospects of the application of organic cooled reactors are briefly outlined. (author)

  6. Nuclear Accidents Archive Knowledge Organization System Portal “NAAKOS”: An Application of Semantic Technologies in the Nuclear Domain

    International Nuclear Information System (INIS)

    Atieh, T.

    2016-01-01

    Full text: In line with the IAEA Action Plan on Nuclear Safety, the IAEA was requested to assist Member States enhancing transparency and effectiveness of communication among operators, regulators and various international organizations, and supporting wide dissemination of safety related technical information on nuclear safety. In this context, the IAEA was further asked to analyse and preserve lessons learned from the Fukushima Daiichi NPP accident, as well as from past major incidents and radiological events. The IAEA NKM Section has launched the Nuclear Accidents Repository Portal Knowledge Organization System “NAAKOS” initiative which aims at collecting and preserving data, information, and knowledge related to nuclear accidents and making this knowledge available through one single access point, while ensuring their long term preservation. The NKM Section has developed the Nuclear Accidents Taxonomy which will be used, along other nuclear taxonomies, to enhance information retrieval. It would also include the use of semantic technologies, data mining and linked data to support users beyond the traditional search facilities. The overall objective is to assist to find predefined measures in a timely manner that could prevent, or at least minimize the adverse effects of incidents. (author

  7. "Fat Man and Little Boy": The Cinematic Representation of Interests in the Nuclear Weapons Organization.

    Science.gov (United States)

    Taylor, Bryan C.

    1993-01-01

    Examines the ironic "problems" of the 1989 Hollywood film "Fat Man and Little Boy" (portraying the construction of the atomic bomb at the Los Alamos Laboratory during World War II) to demonstrate the ideological operations of nuclear texts, and the role of the nuclear weapons organization as a symbolic form in cultural…

  8. Organic materials for the nuclear industry. Guide book for prevention and safe use

    International Nuclear Information System (INIS)

    1988-01-01

    For a safe use of organic materials (plastics, resins, rubbers) in the nuclear industry, this book reviews selection of evaluation of materials by studying their behaviour concerning ionizing radiations, fire resistance and aging [fr

  9. Safety culture of nuclear R and D organizations: A case study

    International Nuclear Information System (INIS)

    Obadiaa, I.J.; Vidalb, M.C.R.; Frutuoso e Melob, P.F.

    2004-01-01

    After the Chernobyl nuclear accident in 1986, the International Atomic Energy Agency (IAEA) established the safety culture concept as a proactive mean to contribute to safety improvement, starting a worldwide safety culture enhancement program within nuclear organizations mainly focused on nuclear power plants. More recently, the safety culture concept has been extended to non-power applications such as nuclear research reactors and nuclear technological research and development organizations. In 1999, the Nuclear Engineering Institute (IEN), a research and technological development unit of the Brazilian Nuclear Energy Commission (CNEN), started a management changing program aiming at improving its performance level of excellence. IEN is classified as a nuclear and radioactive installation, where a nuclear research reactor and two cyclotron-type particle accelerators are operated, and several nuclear and radioactive processes related to industrial, medical and environmental applications are performed. This changing program has been developed based on the assumptions that safety is a fundamental condition for excellence, and safety culture is crucial to the improvement of operational safety. A management system comprised of a safety culture enhancement practice integrated to a quality management process, based on a systematic and adaptive approach, has been developed and implemented at IEN. This paper presents the safety culture enhancement management practice and presents the corresponding evolution of IEN's safety culture and safety indicators results. (author)

  10. Transition from quality assurance to an integrated management system for nuclear organizations

    International Nuclear Information System (INIS)

    Dua, Shami

    2008-01-01

    The integrated performance- based approach to management systems is a business imperative for the nuclear industry to maintain and enhance its share in the energy sector. The compliance approach has served the industry well to protect its employed, neighbourhood and public at large. It is well recognized that industry has to build on this experience and move to the next level. The model described in this paper provides a fairly flexible approach to move towards a more integrated performance based approach to achieve both the compliance and business related goals and objectives. Compliance with quality and safety requirements must remain a key focus for the industry. The model presented provides a practical approach to develop the business and compliance processes and documentation that can be integrated at the job and project execution levels. The product and business performance objectives will be embedded into the system documentation and implementation at all levels by the responsible line units. The model can be easily adapted to meet the requirements of applicable codes and standards and lends itself to obtain ISO and other system and product based certifications. The approach is consistent with the new IAEA direction on the management system requirements as covered in its new series of standards under GS-R-3. As IAEA is planning a number of regional workshops, nuclear organizations planning to transition to the IMS approach should participate and benefit from these workshops. This will further enhance their understanding and application of the IMS concepts and methodologies. IAEA conducted a joint workshop with FORATOM in Vienna, Austria in November 2007 and another is planned in October 2008 jointly with KHNP and PNC in Busan, S.Korea. (author)

  11. Factors Associated with Maintaining the Mental Health of Employees after the Fukushima Nuclear Disaster: Findings from Companies Located in the Evacuation Area.

    Science.gov (United States)

    Orui, Masatsugu; Suzuki, Yuriko; Goto, Aya; Yasumura, Seiji

    2017-12-31

    After the nuclear disaster in Fukushima on 11 March 2011, some businesses were permitted to continue operating even though they were located in the evacuation area designated by the Japanese government. The aim of this study was to examine differences in the mental health status, workplace, living environment, and lifestyle of employees in the evacuation and non-evacuation areas. We also investigated factors related to their mental health status. Data for this cross-sectional study were collected from the questionnaire responses of 647 employees at three medium-sized manufacturing companies in the evacuation and non-evacuation areas. Through a cross-tabulation analysis, employees who worked at companies in the evacuation areas showed an increase in the duration of overtime work, work burden, and commute time, and had experienced separation from family members due to the radiation disaster and perceived radiation risks. The results of a multivariate logistic regression analysis showed that, even in a harsh workplace and living environment, being younger, participating regularly in physical activity, having a social network (Lubben Social Network Scale-6 ≤ 12), laughing frequently, and feeling satisfied with one's workplace and domestic life were significantly associated with maintaining a healthy mental health status after the disaster. These findings are applicable for workers' health management measures after disasters.

  12. Evolutionary Effects on Morphology and Agronomic Performance of Three Winter Wheat Composite Cross Populations Maintained for Six Years under Organic and Conventional Conditions

    Directory of Open Access Journals (Sweden)

    Sarah Brumlop

    2017-02-01

    Full Text Available Three winter wheat (Triticum aestivum L. composite cross populations (CCPs that had been maintained in repeated parallel populations under organic and conventional conditions from the F5 to the F10 were compared in a two-year replicated field trial under organic conditions. The populations were compared to each other, to a mixture of the parental varieties used to establish the CCPs, and to three winter wheat varieties currently popular in organic farming. Foot and foliar diseases, straw length, ear length, yield parameters, and baking quality parameters were assessed. The overall performance of the CCPs differed clearly from each other due to differences in their parental genetics and not because of their conventional or organic history. The CCPs with high yielding background (YCCPs also yielded higher than the CCPs with a high baking quality background (QCCPs; in the absence of extreme winter stress. The QCCPs performed equally well in comparison to the reference varieties, which were also of high baking quality. Compared to the parental mixture the CCPs proved to be highly resilient, recovering much better from winter kill in winter 2011/12. Nevertheless, they were out yielded by the references in that year. No such differences were seen in 2013, indicating that the CCPs are comparable with modern cultivars in yielding ability under organic conditions. We conclude that—especially when focusing on traits that are not directly influenced by natural selection (e.g. quality traits—the choice of parents to establish a CCP is crucial. In the case of the QCCPs the establishment of a reliable high-quality population worked very well and quality traits were successfully maintained over time. However, in the YCCPs lack of winter hardiness in the YCCP parents also became clearly visible under relevant winter conditions.

  13. Organization and liability of British regulating authorities involved in nuclear safety and radiation protection

    International Nuclear Information System (INIS)

    Harbison, S.

    1995-01-01

    In Great Britain, nuclear safety juridic basis is made of two law: HSWA (1974) for hygiene and security in working environment, and NIA (1965) specific to nuclear sites. The HSWA law created an HSC (Hygiene and Security Commission) in charge of workers and public security. HSC executive organ is HSE, whose nuclear office is NSD. Nevertheless, the general philosophy remains the one of HSWA, which results in the liability of operators in nuclear matters, as well as for any other industrial matter. (D.L.). 1 fig., 1 map

  14. Australian Nuclear Science and Technology Organization Act 1987 - No 3 of 1987

    International Nuclear Information System (INIS)

    1987-01-01

    The purpose of this Act (ANSTO Act) is to establish a successor to the Australian Atomic Energy Commission (AAEC) set up under the Atomic Energy Act 1953. The Act provides for a new Organization with functions which, according to Government policy, better reflect the directions in which Australia's principal research organization should tend in that area, namely realignment of AAEC activities away from work on the nuclear fuel cycle, towards greater emphasis on applications of radioisotopes and radiation in medicine, industry, agriculture, science, commerce, etc. ANSTO is prohibited from undertaking any R and D into the design and production of nuclear weapons or nuclear explosive devices. (NEA) [fr

  15. Technical and scientific support organizations and strengthening of nuclear regulation (Case study of Moldova)

    International Nuclear Information System (INIS)

    Buzdugan, Artur; Buzdugan, Aurelian

    2010-01-01

    Authors present arguments for establishing of technical and scientific support organizations (TSO) infrastructure as obligatory components of the national radiation protection and nuclear safety infrastructure. In the small countries, like the Republic of Moldova, characterized by insufficient development of nuclear technologies, different social, economic, scientific and, why not, national peculiarities impose opportunity of efficient interaction of regulatory body with TSO. Are presents certain examples of interaction of those organizations. As mentioned, that synergy of such interaction will contribute essentially in implementation of adequate nuclear culture in the country. (author)

  16. Human performance improvement in organizations: Potential application for the nuclear industry

    International Nuclear Information System (INIS)

    2005-11-01

    This publication is primarily intended for managers and specialists in nuclear facility operating organizations working in the area of human performance improvement. It is intended to provide them with practical information they can use to improve human performance in their organizations. While some of the information provided in this publication is based upon the experience of nuclear facility operating organizations, most of it comes from human performance improvement initiatives in non-nuclear organizations and industries. The nuclear industry has a long tradition of sharing good management practices in order to foster continuous improvement. However, it is not always realized that many of the practices that are now well established initially came from non-nuclear industries and were subsequently adapted for application to nuclear power plant operating organizations. There is, therefore, good reason to periodically review non-nuclear industry practices for ideas that might have direct or indirect application to the nuclear industry in order to potentially gain benefits such as the following: new approaches to certain problem areas, insights into new or impending challenges, improvements in existing practices, benchmarking of opportunities, development of learning organizations and avoidance of collective blind spots. The preparation of this report was an activity of the project on Effective Training to Achieve Excellence in the Performance of NPP Personnel. The objective of this project is to enhance the capability of Member States to utilize proven practices developed and transferred by the IAEA for improving personnel performance. The expected outcome from this project is the increased use by organizations in Members States of proven engineering and management practices and methodologies developed and transferred by the IAEA to improve personnel performance

  17. Activities of nuclear safety culture in foreign organizations such as IAEA, etc

    International Nuclear Information System (INIS)

    Makino, Maomi; Sakaue, Takeharu; Thukuda, Yoshiaki

    2006-01-01

    Safety of nuclear facilities is guaranteed with the safety of instrument and equipment and of human, organization, management and system. In the guarantee, especially the encouragement and the growth of nuclear safety culture which is the basis of the safety of the latter are very important. In recent years, severe accidents and transients due to organizational issues have increased. Then, international organizations, regulatory organizations of each country and nuclear enterprises promote positively the developments of self-assessment methods of safety culture and safety management systems. The activities in the international organizations of IAEA and OECD/NEA and in the foreign regulatory organizations of US NRC and UK NII are described. (K. Kato)

  18. Nuclear organization during in vitro differentiation of porcine mesenchymal stem cells (MSCs) into adipocytes.

    Science.gov (United States)

    Stachecka, Joanna; Walczak, Agnieszka; Kociucka, Beata; Ruszczycki, Błażej; Wilczyński, Grzegorz; Szczerbal, Izabela

    2018-02-01

    Differentiation of progenitor cells into adipocytes is accompanied by remarkable changes in cell morphology, cytoskeletal organization, and gene expression profile. Mature adipocytes are filled with a large lipid droplet and the nucleus tends to move to the cell periphery. It was hypothesized that the differentiation process is also associated with changes of nuclear organization. The aim of this study was to determine the number and distribution of selected components of nuclear architecture during porcine in vitro adipogenesis. The pig is an important animal model sharing many similarities to humans at the anatomical, physiological, and genetic levels and has been recognized as a good model for human obesity. Thus, understanding how cellular structures important for fundamental nuclear processes may be altered during adipocyte differentiation is of great importance. Mesenchymal stem cells (MSCs) were derived from bone marrow (BM-MSCs) and adipose tissue (AD-MSCs) and were cultured for 7 days in the adipogenic medium. A variable differentiation potential of these cell populations towards adipogenic lineage was observed, and for further study, a comparative characteristic of the nuclear organization in BM-MSCs and AD-MSCs was performed. Nuclear substructures were visualized by indirect immunofluorescence (nucleoli, nuclear speckles, PML bodies, lamins, and HP1α) or fluorescence in situ hybridization (telomeres) on fixed cells at 0, 3, 5, and 7 days of differentiation. Comprehensive characterization of these structures, in terms of their number, size, dynamics, and arrangement in three-dimensional space of the nucleus, was performed. It was found that during differentiation of porcine MSCs into adipocytes, changes of nuclear organization occurred and concerned: (1) the nuclear size and shape; (2) reduced lamin A/C expression; and (3) reorganization of chromocenters. Other elements of nuclear architecture such as nucleoli, SC-35 nuclear speckles, and telomeres

  19. Organization of radiation protection in German nuclear power stations

    International Nuclear Information System (INIS)

    1989-01-01

    Using the operating handbooks of the nuclear power stations in West Germany, an examination was carried out of how far the existing organisational structure for radiation protection fulfils the requirements for protection and whether a standardisation of the organisation would provide improvements for the protection of the personnel and for the practicability of the radiation protection organisation. In particular, the parts 'Personnel operating organisation', 'Radiation protection order' and 'Maintenance order' of the operating handbook were evaluated and an audit was made of the radiation protection organisation. In general, the result of the assessment is that the organisation of radiation protection does not contradict the orders, guidelines and regulations in any of the nuclear power stations examined. Corresponding to the possibilities of regulating details of the radiation protection organisation within the undertaking, the target of 'protection of the personnel against radioactive irradiation' is achieved by the various organisation structures which are largely equal to the given example. (orig./HP) [de

  20. KNOWBOT: a self-organizing interface for nuclear data bases

    International Nuclear Information System (INIS)

    Heger, A.S.; Koen, B.V.

    1988-01-01

    This paper describes the development of a practical intelligent associate, KNOWBOT, designed to act as a surrogate for engineers and scientists in accessing nuclear power industry data bases. The nuclear power industry has developed several safety and reliability data bases to facilitate the exchange of significant safety-related data for enhancement of its performance. The nuclear plant reliability data system and the licensee event reports are instances of such data bases. The creation of these data bases has, nevertheless, been paradoxical. They have provided rapid access to the needed data. Yet they have, at the same time, created their own impediments. Two of these problems that are addressed by the design of KNOWBOT are the interface and dimensionality. The interface problem falls in the broader category of man/machine interaction, which deals with the problems involved with this symbiosis. Dimensionality deals with the rapidly increasing sizes of the data bases and their ability to process queries in a timely fashion. Numerous programs have been developed to address the interface problem, but most have proven inadequate in real-time applications. The dimensionality problem has been approached through the development of faster processors and query optimizers. As these data bases continue to expand, the present solutions are reaching their performance limits, and a new approach such as that offered by KNOWBOT is needed

  1. Organization and regulation of nuclear medicine and radiotherapy in Argentina

    International Nuclear Information System (INIS)

    Degrossi, O.J.; Altschuler, Noe; Mugliaroli, H.A.

    1982-01-01

    After describing the efforts carried out in Argentina during the decade of 1970 to consolidate nuclear medicine as a new clinical specialty, reference is made to the constitution, in 1979, of a Joint Advisory Committee on Nuclear Medicine and Radiotherapy integrated by members of the National Atomic Energy Commission and by members of the Public Health Ministry of the Nation, with the purpose to coordinate and plan said activities within the country. Two recommendations of said Advisory Committee are transcribed. The first one defines the different specialties of the professionals and technicians working in the new discipline. The second recommendation is referred to the regulations on ''Operation of Nuclear Medicine Units'', which set up different categories of medical establishments of the specialty (''unit'', ''service'' and ''center''), define their respective functions as well as the equipment and specialized personnel that they should be fitted with in each case, and institute the requirement to demonstrate having the corresponding academic and professional up-dating in the specialty to obtain the periodic revalidation of operation licences. (C.A.K.) [es

  2. Prestigious nuclear research organization orders Silicom's cutting-edge server adapters

    CERN Multimedia

    2003-01-01

    "Silicom Ltd today announced that one of the world's largest and most prestigious nuclear research organization has placed an initial order for its Gigabit Ethernet Server Adapters. Silicom's high-performance adapters will be deployed in the organization's state-of-the-art particle physics laboratory servers to help them attain reliable gigabit transfer rates" (1/2 page).

  3. Present state of nuclear regulation organizations of main countries in the world. Importance of regulation staffs and requirements

    International Nuclear Information System (INIS)

    Nishida, Naoki

    2013-01-01

    After Fukushima accident, NRA (Nuclear Regulation Authority) was established in Japan as an independent organization from promotion. In order to perform effective and reliable nuclear regulation, it was important management organization such as nuclear regulation commission worked efficiently, and also requirements for nuclear regulation staffs engaged in actual regulatory works were of importance so as for appropriate decision making or judgments of management organization. Since regulation staffs needed professional expertise and technical judgment capabilities in wide areas including other than nuclear energy, various efforts had been done to get able regulation staffs in US, France and UK nuclear regulation organizations concerned, which became clarified after overseas investigation for this article. Since knowledge in nuclear industry could be used for effective regulation, mid-career recruitment had been employed in regulation organization of each country so as to take such knowledge and so it was important how to utilize industrial knowledge under appropriate conditions compatible with independence of regulation organization. (T. Tanaka)

  4. Role of a national research organization in the transfer of nuclear technology

    International Nuclear Information System (INIS)

    Ahmad, Ishaq

    1977-01-01

    Nuclear technology holds great promise for developing countries because it can contribute to national development. The developing countries, however, lack the resources and expertise to develop nuclear technology through their own efforts. A national research organization devoted to the promotion and utilization of nucler technology can provide an effective channel for the transfer of nuclear technology. The problems which the national research organization is likely to face in executing its tasks as an agent for the transfer of technology are discussed. An appreciation of these problems would enable the organization to restructure its priorities so as to achieve maximum effectiveness. The various ways by which the national research organization can speed up the task of transfer of technology are also discussed

  5. Spectrographic determination of metallic impurities in organic coolants for nuclear reactors

    International Nuclear Information System (INIS)

    Martin Munoz, M.; Alvarez Gonzalez, F.

    1969-01-01

    A spectrochemical method for determining metallic impurities in organic coolants for nuclear reactors is given. The organic matter in solid samples is eliminated by controlled distillation and dry ashing in the presence of magnesium oxide as carrier. Liquid, samples are vacuum distillated. The residue is analyzed by carrier distillation and by total burning techniques. The analytical results are discussed and compared with those obtained destroying the organic matter without carrier and using the copper spark technique. (Author) 12 refs

  6. Recycling of Organic Wastes to Achieve the Clean Agriculture Approach with Aid of Nuclear Techniques

    International Nuclear Information System (INIS)

    Moursy, A.A.A.

    2012-01-01

    The Objective of this current work is to study Organic matter decomposition under clean agriculture system in sandy soil using nuclear technique. This desirtatation has the following targets: - Amendment and improving sandy soil properties - Utilization of farm wastes (Recycling) in safe mode -Benefits form organic matter decomposition. - Follow up the fate of same nutrients (Nitrogen) released in soil media after organic matter (O.M) decomposition and Impact on plant nutrition status.-saving the environment on short and long run.

  7. Aging and oxidatively damaged nuclear DNA in animal organs

    DEFF Research Database (Denmark)

    Møller, Peter; Løhr, Mille; Folkmann, Janne K

    2010-01-01

    with limited cell proliferation, i.e., liver, kidney, brain, heart, pancreas, and muscle, tended to show accumulation of DNA damage with age, whereas organs with highly proliferating cells, such as intestine, spleen, and testis, showed more equivocal or no effect of age. A restricted analysis of studies......Oxidative stress is considered to contribute to aging and is associated with the generation of oxidatively damaged DNA, including 8-oxo-7,8-dihydroguanine. We have identified 69 studies that have measured the level of oxidatively damaged DNA in organs of animals at various ages. In general, organs...... reporting a baseline level of damaged DNA that was fewer than 5 lesions/10(6) dG showed that 21 of 29 studies reported age-associated accumulation of DNA damage. The standardized mean difference in oxidatively damaged DNA between the oldest and the youngest age groups was 1.49 (95% CI 1...

  8. Estimated Organ Doses to Patients from Diagnostic Nuclear Medicine Examinations over Five Decades: 1960-2010.

    Science.gov (United States)

    Villoing, Daphnée; Drozdovitch, Vladimir; Simon, Steven L; Kitahara, Cari M; Linet, Martha S; Melo, Dunstana R

    2017-12-01

    Ionizing radiation exposure to the general U.S. population nearly doubled between 1980 and 2006, due almost entirely to the significant increase in the number of radiologic and nuclear medicine procedures performed. Significant changes in the types of procedures and radionuclides used in nuclear medicine, as well as in detection technology, have led to notable changes over time in absorbed doses to specific organs. This study is the first to estimate per-procedure organ doses to nuclear medicine patients and trends in doses over five decades. Weighted average organ doses per examination to 14 organs of interest were calculated for 17 examination types over 10 5-y time periods (1960-2010) as the product of the percentage of use of each radiopharmaceutical in those diagnostic procedures based on comprehensive literature review, the administered activity, and ICRP dose coefficients; doses per radiopharmaceutical were also provided for each organ, procedure, and time period. The weighted doses to adult nuclear medicine patients from cardiac procedures increased to all organs of interest between 1960 and 2010 except for the urinary bladder wall. From high radiation doses for most other procedures in the 1960s, with up to 0.7 Gy in the specific case of radioiodinated thyroid scans, organ-absorbed doses generally decreased from 1960 to 1990. In contrast, during the 1990s and 2000s, the weighted doses were gradually increased for some procedures, such as brain and skeleton scans. The increasing number of nuclear medicine procedures, specifically cardiac scans and changes in weighted doses, underscore the need to monitor exposure levels and radiation-related disease risks in nuclear medicine patients.

  9. Air Force Nuclear Enterprise Organization: A Case Study

    Science.gov (United States)

    2016-09-15

    Usmani 2012). Similar to the simple structure, the key advantage also contributes to disadvantages . Because functional organizations work best with...By taking the design parameters, external influences and the advantages or disadvantages of various organizational structures into consideration...need additional research to analyze financial, manning and other logistical advantages or disadvantages associated with change recommendations

  10. Challenges Faced by Regulators and Technical, Scientific and Support Organizations (TSOs) in Enhancing Nuclear Safety and Security

    International Nuclear Information System (INIS)

    Travers, W.D.

    2011-01-01

    Renewed interest in new reactor build programmes, not only in countries with already established nuclear programmes but also in many other countries with limited or no workforce experienced in the design, licensing, construction and operation of nuclear power plants, has resulted in a need for technical, scientific and support organizations (TSOs) to support regulatory bodies in carrying out their mandated responsibilities. The primary function of a regulatory body, such as the Federal Authority for Nuclear Regulation (FANR) in the United Arab Emirates (UAE), is to regulate the safe use of nuclear facilities and radioactive material for peaceful civilian purposes. In so doing, the regulatory body needs to provide a clear and focused approach to: safety, security and safeguards for licensing; inspection and enforcement of reactor design; construction; commissioning; operation; decommissioning; nuclear waste management activities; and the use, possession or transfer of special nuclear materials and activities within the country. Accomplishing this goal requires a highly educated, multidisciplinary, diverse workforce with significant work experience. Recognizing that it takes several decades and a lot of resources to achieve self-sufficiency, many countries, particularly emergent nuclear countries, would have to rely on TSOs to start their programmes and to carry out their oversight responsibilities. Towards that end, FANR is working closely with international counterparts, the International Atomic Energy Agency and TSOs to exchange information, expertise, industry experience and ongoing research to ensure that high levels of safety, security and safeguards are established and maintained in reactor design and operation throughout the life of the facility, and that special nuclear material within the UAE is properly documented and controlled, is not stolen, lost or diverted to any illicit or non-peaceful activities, and does not pose unreasonable radiological risk due

  11. Nuclear power and the nuclear fuel cycle

    International Nuclear Information System (INIS)

    Scurr, I.F.; Silver, J.M.

    1990-01-01

    Australian Nuclear Science and Technology Organization maintains an ongoing assessment of the world's nuclear technology developments, as a core activity of its Strategic Plan. This publication reviews the current status of the nuclear power and the nuclear fuel cycle in Australia and around the world. Main issues discussed include: performances and economics of various types of nuclear reactors, uranium resources and requirements, fuel fabrication and technology, radioactive waste management. A brief account of the large international effort to demonstrate the feasibility of fusion power is also given. 11 tabs., ills

  12. Nuclear power plant training simulator modeling organization and method

    International Nuclear Information System (INIS)

    Alliston, W.H.

    1975-01-01

    A description is given of a training simulator for the full-scope real-time dynamic operation of a nuclear power plant which utilizes apparatus that includes control consoles having manual and automatic devices corresponding to simulated plant components and indicating devices for monitoring physical values in the simulated plants. A digital computer configuration is connected to the control consoles to calculate the dynamic real-time simulated operation of the plant in accordance with the simulated plant components to provide output data including data for operating the control console indicating devices. The plant simulation is modularized into various plant components or component systems. Simulated plant components or component systems are described by a mathematical equation embodied in a computer program which accepts data from other simulated plant components or systems, calculates output values including values which are used as inputs for simulator calculators by other simulated plant components or systems, and responds in a manner similar to that of its corresponding physical entity in both transient and steady states

  13. European Organization for Nuclear Research annual report 1976

    International Nuclear Information System (INIS)

    1977-01-01

    The 1976 CERN annual report begins with a brief history of the organization and description of the organizational structure. A description of the CERN accelerators is given and CERN scientific activities are reviewed. The main body of the report comprises reports from the eleven main divisions, and administrative divisions such as personnel and finance. The reports from the scientific divisions contain descriptions of, and data from, present research and plans for long term development. The appendices contain a list of CERN publications for 1976, a list of lectures and seminars held, a list of training programmes undertaken and a list of scientific conferences and schools held. (B.D.)

  14. Precipitate hydrolysis process for the removal of organic compounds from nuclear waste slurries

    Science.gov (United States)

    Doherty, J.P.; Marek, J.C.

    1987-02-25

    A process for removing organic compounds from a nuclear waste slurry comprising reacting a mixture of radioactive waste precipitate slurry and an acid in the presence of a catalytically effective amount of a copper(II) catalyst whereby the organic compounds in the precipitate slurry are hydrolyzed to form volatile organic compounds which are separated from the reacting mixture. The resulting waste slurry, containing less than 10 percent of the original organic compounds, is subsequently blended with high level radioactive sludge land transferred to a vitrification facility for processing into borosilicate glass for long-term storage. 2 figs., 3 tabs.

  15. The Nuclear Organization and Management Analysis Concept methodology: Four years later

    International Nuclear Information System (INIS)

    Haber, S.B.; Shurberg, D.A.; Barriere, M.T.; Hall, R.E.

    1992-01-01

    The Nuclear Organization and Management Analysis Concept was first presented at the IEEE Human Factors meeting in Monterey in 1988. In the four years since that paper, the concept and its associated methodology has been demonstrated at two commercial nuclear power plants (NPP) and one fossil power plant. In addition, applications of some of the methods have been utilized in other types of organizations, and products are being developed from the insights obtained using the concept for various organization and management activities. This paper will focus on the insights and results obtained from the two demonstration studies at the commercial NPPs. The results emphasize the utility of the methodology and the comparability of the results from the two organizations

  16. Organizations putting in place in case of accident in a french nuclear power plant

    International Nuclear Information System (INIS)

    Noc, B.; Queniart, D.

    1987-01-01

    In case of accident entraining radiological consequences on or near the site of nuclear power reactor, organizations are putting in place. These organizations include as well as side of operating authority (generally Electricite de France) or public organizations including safety organizations (Service Central de Surete des Installations Nucleaires, Institut de Protection et de Surete Nucleaire), one local organization and one centralized national organization. Informations exchange and coordination necessary between these organizations are governed by protocols. These protocols include particularly, the problems of mobilizing experts and of dealing with the saturation of normal telecommunications channels. The lessons acquired during accident simulation exercises carried out in recent years are progressively put in place in these protocols [fr

  17. Seminar on the organization and management of a commercial nuclear power project

    International Nuclear Information System (INIS)

    Peddicord, K.L.; Alvis, J.M.; Chitkara, K.K.

    1986-01-01

    A main function of student branches of the American Nuclear Society (ANS) is to identify activities that contribute to the professional development and growth of its student members. Over the past several years, the ANS student branch at Texas A and M University has toured the construction site of the South Texas Nuclear Project (STNP), which is jointly owned by the Houston Lighting and Power Company (HL and P), the City of San Antonio, the Central Power and Light Company, and the City of Austin. This year, student branch organizers recognized that another aspect of a commercial nuclear power plant was not being covered either in the academic course work or the plant tours. This facet includes the organization and management required to undertake a major nuclear power project. To fill this gap, HL and P sponsored a one-day seminar that covered the various managerial functions for STNP. The seminar on the Organization and Management at a Commercial Nuclear Power Project was very interesting and beneficial. Other ANS branches and utilities may find this to be a useful model for future activities

  18. Maintainability design guide

    International Nuclear Information System (INIS)

    Pack, R.W.

    1985-01-01

    The Human Factors Design Guide for Maintainability provides guidance for systematically incorporating good human factors techniques into the design of power plants. The guide describes a means of developing a comprehensive program plan to ensure compliance with the human factors approaches specified by the utility. The guide also provides specific recommendations for design practices, with examples, bases, and references. The recommendations are formatted for easy use by nuclear power plant design teams and by utility personnel involved in specification and design review. The guide was developed under EPRI research project RP2166-4 and is currently being published

  19. Constructability and maintainability

    International Nuclear Information System (INIS)

    Hart, R.S.

    1985-01-01

    A set of principles for minimizing the construction schedule was established at the outset of the CANDU 300 programme. Consideration of these principles and other factors led to the development of the unique CANDU 300 station layout. The paper discusses the CANDU 300 station layout and construction methods. In summary, the station layout provides 360 deg. construction access to all buildings, separation of nuclear and non-nuclear systems, precise and minimal physical interfaces between buildings, accommodation of many contractors and construction activities without interference, and maximum flexibility in terms of constructional, financial and supply arrangements. The CANDU 300 further employs modularization, shop fabrication and advanced instrumentation (multiplexers, remote processors, data highways) to minimize construction time. Many of the CANDU 300 features that enhance constructability also contribute to maintainability. These include the 360 deg. access to all principal buildings, the uncluttered and spacious building layouts, the simplification of systems and the high level of modularization. The CANDU 300 has also been designed to facilitate the replacement of all key components, thereby offering an essentially unlimited station life. A prime example is a reduction in the fuel channel inlet end-fitting diameter such that the fuel channels can be shop assembled and easily replaced after the initial 40 years of operation, without an extended unit outage. Maintainability within the reactor building has been given particular attention in the CANDU 300 design; key features of other CANDU reactors (the ability to replace a heat transport system pump motor at power, for example) have been incorporated, while accessibility and maintainability of all systems and components have been enhanced. These and other aspects of maintainability are discussed. (author)

  20. Organizing for change: new priorities for training organization in the nuclear industry

    International Nuclear Information System (INIS)

    Gammuto, J.J.

    1981-01-01

    Traditional training organizations will require a new look in light of the efforts being applied since TMI. the emphasis to incorporate basic educational technology into power plant training and trends of past, present, and future program development, point out the need for change in training philosophy and manpower needs. The functional responsibilities within a typical training organization will be described with an emphasis on interrelationships of each group activity and the effect of the systems approach to training organization and administration

  1. Nuclear magnetic resonance of laser-polarized noble gases in molecules, materials and organisms

    Energy Technology Data Exchange (ETDEWEB)

    Goodson, Boyd McLean [Univ. of California, Berkeley, CA (United States)

    1999-12-01

    Conventional nuclear magnetic resonance (NMR) spectroscopy and magnetic resonance imaging (MRI) are fundamentally challenged by the insensitivity that stems from the ordinarily low spin polarization achievable in even the strongest NMR magnets. However, by transferring angular momentum from laser light to electronic and nuclear spins, optical pumping methods can increase the nuclear spin polarization of noble gases by several orders of magnitude, thereby greatly enhancing their NMR sensitivity. This dissertation is primarily concerned with the principles and practice of optically pumped nuclear magnetic resonance (OPNMR). The enormous sensitivity enhancement afforded by optical pumping noble gases can be exploited to permit a variety of novel NMR experiments across many disciplines. Many such experiments are reviewed, including the void-space imaging of organisms and materials, NMR and MRI of living tissues, probing structure and dynamics of molecules in solution and on surfaces, and zero-field NMR and MRI.

  2. Nuclear magnetic resonance of laser-polarized noble gases in molecules, materials and organisms

    International Nuclear Information System (INIS)

    Goodson, Boyd M.

    1999-01-01

    Conventional nuclear magnetic resonance (NMR) spectroscopy and magnetic resonance imaging (MRI) are fundamentally challenged by the insensitivity that stems from the ordinarily low spin polarization achievable in even the strongest NMR magnets. However, by transferring angular momentum from laser light to electronic and nuclear spins, optical pumping methods can increase the nuclear spin polarization of noble gases by several orders of magnitude, thereby greatly enhancing their NMR sensitivity. This dissertation is primarily concerned with the principles and practice of optically pumped nuclear magnetic resonance (OPNMR). The enormous sensitivity enhancement afforded by optical pumping noble gases can be exploited to permit a variety of novel NMR experiments across many disciplines. Many such experiments are reviewed, including the void-space imaging of organisms and materials, NMR and MRI of living tissues, probing structure and dynamics of molecules in solution and on surfaces, and zero-field NMR and MRI

  3. Organization and conduct of IAEA fire safety reviews at nuclear power plants

    International Nuclear Information System (INIS)

    1998-01-01

    The importance of fire safety in the safe and productive operation of nuclear power plants is recognized worldwide. Lessons learned from experience in nuclear power plants indicate that fire poses a real threat to nuclear safety and that its significance extends far beyond the scope of a conventional fire hazard. With a growing understanding of the close correlation between the fire hazard in nuclear power plants and nuclear safety, backfitting for fire safety has become necessary for a number of operating plants. However, it has been recognized that the expertise necessary for a systematic independent assessment of fire safety of a NPP may not always be available to a number of Member States. In order to assist in enhancing fire safety, the IAEA has already started to offer various services to Member States in the area of fire safety. At the request of a Member State, the IAEA may provide a team of experts to conduct fire safety reviews of varying scope to evaluate the adequacy of fire safety at a specific nuclear power plant during various phases such as construction, operation and decommissioning. The IAEA nuclear safety publications related to fire protection and fire safety form a common basis for these reviews. This report provides guidance for the experts involved in the organization and conduct of fire safety review services to ensure consistency and comprehensiveness of the reviews

  4. Subcritical wet air oxidation of organic solvents and chelating agents of the nuclear fuel

    International Nuclear Information System (INIS)

    Bachir, Souley

    1999-01-01

    This document deals with the environment control, more specially organic solvents and chelating agents destruction, employed in the nuclear industry. This work details the subcritical wet air oxidation process. Another part of the document deals with the possible coupling between this process and the biodegradation technic in the framework of the sewage sludges treatment. (A.L.B.)

  5. Improving performance of high risk organizations Spanish nuclear sector from the analysis of organizational culture factors

    International Nuclear Information System (INIS)

    La Salabarnada, E.; German, S.; Silla, I.; Navajas, J.

    2012-01-01

    This paper presents the research project funded by UNESA and conducted by the CISOT-CIEMAT that aims to contribute to improving the operating performance of the Spanish nuclear power plants. This paper aims to identify the factors and key organizational processes to improve efficiency, in order to advance knowledge about the influence of organizational culture on the safety of high reliability organizations.

  6. Australian Nuclear Science and Technology Organization (Transitional Provisions) Act 1987 - No 4 of 1987

    International Nuclear Information System (INIS)

    1987-01-01

    This Act implements certain transitional provisions consequent to the enactment of the ANSTO Act 1987. The legislation provides for the continuation of the body corporate from its present form as the Australian Atomic Energy Commission to the new body corporate, the Australian Nuclear Science and Technology Organization. (NEA) [fr

  7. Planning and Execution of Knowledge Management Assist Missions for Nuclear Organizations (Russian Edition)

    International Nuclear Information System (INIS)

    2012-06-01

    As a result of the widening knowledge gap in the nuclear industry and related organizations, the IAEA is developing a series of guidance documents on knowledge management. This publication represents one such activity and provides general guidance as to the nature of the knowledge management mission and the means by which its goals are to be achieved and executed.

  8. Nuclear power can reduce emissions and maintain a strong economy: Rating Australia’s optimal future electricity-generation mix by technologies and policies

    International Nuclear Information System (INIS)

    Hong, Sanghyun; Bradshaw, Corey J.A.; Brook, Barry W.

    2014-01-01

    Highlights: • Nuclear power is essential for reducing greenhouse-gas emissions at lower cost. • Physical and economic limits of renewables at high penetrations hamper their growth. • Large-scale fossil fuels are required if nuclear power is not permitted in Australia. • Well-balanced information is a prerequisite for defining an optimal future mix. - Abstract: Legal barriers currently prohibit nuclear power for electricity generation in Australia. For this reason, published future electricity scenarios aimed at policy makers for this country have not seriously considered a full mix of energy options. Here we addressed this deficiency by comparing the life-cycle sustainability of published scenarios using multi-criteria decision-making analysis, and modeling the optimized future electricity mix using a genetic algorithm. The published ‘CSIRO e-future’ scenario under its default condition (excluding nuclear) has the largest aggregate negative environmental and economic outcomes (score = 4.51 out of 8), followed by the Australian Energy Market Operator’s 100% renewable energy scenario (4.16) and the Greenpeace scenario (3.97). The e-future projection with maximum nuclear-power penetration allowed yields the lowest negative impacts (1.46). After modeling possible future electricity mixes including or excluding nuclear power, the weighted criteria recommended an optimized scenario mix where nuclear power generated >40% of total electricity. The life-cycle greenhouse-gas emissions of the optimization scenarios including nuclear power were <27 kg CO 2 -e MW h −1 in 2050, which achieves the IPCC’s target of 50–150 kg CO 2 -e MW h −1 . Our analyses demonstrate clearly that nuclear power is an effective and logical option for the environmental and economic sustainability of a future electricity network in Australia

  9. Role of international organizations in promoting nuclear medicine in the developing countries

    International Nuclear Information System (INIS)

    Nofal, M.

    1992-01-01

    Today, because of the diversity of its applications - radiation and radionuclides for medical and biological purposes are used in more countries and in more laboratories than any other application of atomic energy. International organizations, mainly the IAEA and the WHO, have played a significant role in the spread of this nuclear technology in developing countries. There are altogether 112 member states of the Agency, about 71 of them can be classified as developing countries. Out of them, nearly 56 have some kind of nuclear medicine. By that I mean there is some medical use of radioisotopes, be it imaging, radioimmunoassay or the old thyroid uptake. In most of these countries, the personnel working in nuclear medicine has been trained abroad. Training can be as short as few weeks abroad in the form of attendance at one of the four or six week training courses offered by an international organization. Occasionally it is through a fellowship offered by the same organizations. In terms of technology and training, Nuclear Medicine, in its present form, can thus be considered a high technology imported medicine in many of these countries

  10. Nuclear Calcium Signaling Induces Expression of the Synaptic Organizers Lrrtm1 and Lrrtm2*

    Science.gov (United States)

    Hayer, Stefanie N.; Bading, Hilmar

    2015-01-01

    Calcium transients in the cell nucleus evoked by synaptic activity in hippocampal neurons function as a signaling end point in synapse-to-nucleus communication. As an important regulator of neuronal gene expression, nuclear calcium is involved in the conversion of synaptic stimuli into functional and structural changes of neurons. Here we identify two synaptic organizers, Lrrtm1 and Lrrtm2, as targets of nuclear calcium signaling. Expression of both Lrrtm1 and Lrrtm2 increased in a synaptic NMDA receptor- and nuclear calcium-dependent manner in hippocampal neurons within 2–4 h after the induction of action potential bursting. Induction of Lrrtm1 and Lrrtm2 occurred independently of the need for new protein synthesis and required calcium/calmodulin-dependent protein kinases and the nuclear calcium signaling target CREB-binding protein. Analysis of reporter gene constructs revealed a functional cAMP response element in the proximal promoter of Lrrtm2, indicating that at least Lrrtm2 is regulated by the classical nuclear Ca2+/calmodulin-dependent protein kinase IV-CREB/CREB-binding protein pathway. These results suggest that one mechanism by which nuclear calcium signaling controls neuronal network function is by regulating the expression of Lrrtm1 and Lrrtm2. PMID:25527504

  11. Nuclear calcium signaling induces expression of the synaptic organizers Lrrtm1 and Lrrtm2.

    Science.gov (United States)

    Hayer, Stefanie N; Bading, Hilmar

    2015-02-27

    Calcium transients in the cell nucleus evoked by synaptic activity in hippocampal neurons function as a signaling end point in synapse-to-nucleus communication. As an important regulator of neuronal gene expression, nuclear calcium is involved in the conversion of synaptic stimuli into functional and structural changes of neurons. Here we identify two synaptic organizers, Lrrtm1 and Lrrtm2, as targets of nuclear calcium signaling. Expression of both Lrrtm1 and Lrrtm2 increased in a synaptic NMDA receptor- and nuclear calcium-dependent manner in hippocampal neurons within 2-4 h after the induction of action potential bursting. Induction of Lrrtm1 and Lrrtm2 occurred independently of the need for new protein synthesis and required calcium/calmodulin-dependent protein kinases and the nuclear calcium signaling target CREB-binding protein. Analysis of reporter gene constructs revealed a functional cAMP response element in the proximal promoter of Lrrtm2, indicating that at least Lrrtm2 is regulated by the classical nuclear Ca(2+)/calmodulin-dependent protein kinase IV-CREB/CREB-binding protein pathway. These results suggest that one mechanism by which nuclear calcium signaling controls neuronal network function is by regulating the expression of Lrrtm1 and Lrrtm2. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  12. Long-term management of Canada's spent nuclear fuel: the nuclear waste management organizations recommendation to government

    International Nuclear Information System (INIS)

    Shaver, K.

    2006-01-01

    Full text: Like many countries with nuclear power programs, Canada is in the process of addressing the long-term management of its spent fuel. The Nuclear Waste Management Organization (NWMO) was tasked through federal legislation to conduct a three-year study of approaches for the long-term management of spent fuel, and to recommend a preferred approach to the Government of Canada. Legislation required NWMO to compare at least three approaches -approaches based on deep geological disposal in the Canadian Shield, storage at nuclear reactor sites, and centralized storage either above or below ground. In assessing the options, NWMO sought a recommendation that would be socially acceptable, technically sound, environmentally responsible and economically feasible. The study drew on a vast base of social, technical, engineering, and financial research, and included an extensive engagement program with the public and Aboriginal peoples. The recommendation emerged from a collaborative dialogue with specialists and citizens, for an approach that is built on sound science and technology and responsive to citizen values. NWMO submitted its completed options study, with recommendation, to the Government in November 2005. NWMO has proposed an alternative approach, Adaptive Phased Management, which has as its key attributes: central containment and isolation of spent fuel in a deep repository, in an appropriate geological formation; contingency provision for central shallow storage; monitoring and retrievability; and a staged, adaptive process of concept implementation, reflecting the complex nature of the task and the desire of citizens to proceed through cautious, deliberate steps of technical demonstration and social acceptance. This paper will review: 1) the development of the assessment framework for comparing the technical options, which incorporated social and ethical considerations expressed by citizens; 2) findings of the assessment; and 3) features of the proposed

  13. Nuclear material safeguards technology development in the new structure of BATAN organization

    International Nuclear Information System (INIS)

    Ilyas, Zurias

    2001-01-01

    Full text: The implementation of Nuclear Energy Act No. 10/97 has led to a restructuring in BATAN organization in July 1999. A new unit, Center for Nuclear Material Safeguards Technology (PTPBN), was established to be especially in charge of safeguards facilities. The main responsibility of this unit is to develop the technology of safeguards and physical protection. The function of this unit is also to analyze the operational technical aspect of the International Convention of Nuclear. The duties of Center for Nuclear Material Safeguards Technology can be seen from the various programs set up for every fiscal year. The programs for the year 2000 were: Analyses of SSAC implementation in BATAN; Development of Safeguards information system; Creation of database of physical protection technology; Physical protection simulator for Bandung reactor research; Development of detector technology for physical protection system; Identification of BATAN activities and facilities submitted to IAEA in order to be in line with the Additional Protocol to the agreement between the Republic of Indonesia and the International Atomic Energy Agency for the Application of Safeguards in connection with the Treaty on Non-Proliferation on Nuclear Weapons, which was ratified on September 29th, 1999 in Vienna, Austria; Seminar on Safeguards technology held in Jakarta in September 2000. The program of 2001 will be focusing on the continuation of the previous year's program as well as the creation of new ones, such as: Collaboration with other countries. At initial stage experts from JBC-Japan were invited to share their expertise on their safeguards information system; Development of education and training for safeguards operators by emphasizing more on the techniques of nuclear materials measurement; Seminar on Safeguards technology scheduled for December 2001 by inviting experts from IAEA and modem countries; Field survey to determine the location of radionuclide station in Indonesia in

  14. Search for Erzion nuclear catalysis chains from cosmic ray Erzions stopping in organic scintillator

    International Nuclear Information System (INIS)

    Bazhutov, Yu.N.; Pletnikov, E.V.

    2006-01-01

    In the framework of Erzion model, charged cosmic ray Erzions stopping in organic substance begin to create Erzion nuclear catalysis chains with frequency of ∼ 100 MHz during ∼ 10-100 ms. Using an organic substance (plastic) scintillator we can observe long and flat (10-100 ms) pulses of large amplitude (∼100 MeV). No elementary particle can imitate such pulses. It is expected that such pulses in a plastic scintillator with mass of 100 kg will appear at the sea level every week. Such pulses can be observed every day with the Spectrometric Scintillation Super-Telescope (SSTIS) built at IZMIRAN for cosmic rays monitoring. (authors)

  15. Material degradation of liquid organic semiconductors analyzed by nuclear magnetic resonance spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Fukushima, Tatsuya; Yamamoto, Junichi; Fukuchi, Masashi; Kaji, Hironori, E-mail: kaji@scl.kyoto-u.ac.jp [Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011 (Japan); Hirata, Shuzo; Jung, Heo Hyo; Adachi, Chihaya [Center for Organic Photonics and Electronics Research (OPERA), Kyusyu University, 744 Motooka, Nishi, Fukuoka 819-0395 (Japan); Hirata, Osamu; Shibano, Yuki [Nissan Chemical Industries, LTD, 722-1 Tsuboi, Funabashi 274-8507 (Japan)

    2015-08-15

    Liquid organic light-emitting diodes (liquid OLEDs) are unique devices consisting only of liquid organic semiconductors in the active layer, and the device performances have been investigated recently. However, the device degradation, especially, the origin has been unknown. In this study, we show that material degradation occurs in liquid OLEDs, whose active layer is composed of carbazole with an ethylene glycol chain. Nuclear magnetic resonance (NMR) experiments clearly exhibit that the dimerization reaction of carbazole moiety occurs in the liquid OLEDs during driving the devices. In contrast, cleavages of the ethylene glycol chain are not detected within experimental error. The dimerization reaction is considered to be related to the device degradation.

  16. Qualitative analysis of the man-organization system in accident conditions for nuclear installations

    International Nuclear Information System (INIS)

    Farcasiu, Mita; Prisecaru, Ilie

    2010-01-01

    In this paper a model of the human performance investigation of accident conditions in the operation of the nuclear installation is developed. A framework for analyses of the human action in the man-organization system context is achieved. The goal of this model is to identify the possible roots causing human errors which could occur during the evolution of the accident by the qualitative analysis of the interfaces in man-organization system. These interfaces represent the main elements which characterize the implication of the organization in human performance. The results of this paper are the interfaces of the man-organization and their circumstances in which human performance could fail. Also, another result is a pre-designed framework which could help in the investigation of an accident. (authors)

  17. Planning and execution of knowledge management assist missions for nuclear organizations

    International Nuclear Information System (INIS)

    2008-05-01

    problems. The IAEA is implementing a special subprogram on Nuclear Knowledge Management with a focus on the development of guidance for KM, on networking nuclear education and training and on the preservation of nuclear knowledge. Knowledge management consists of three fundamental components: people, processes and technology. Knowledge management focuses on people and organizational culture to stimulate and nurture the sharing and use of knowledge; on processes or methods to find, create, capture and share knowledge; and on technology to store and make knowledge accessible which will allow people to work together without being located together. People are the most important component. Managing knowledge depends upon people's willingness to share and reuse knowledge. In 2005, the IAEA introduced the concept of KM missions. The missions were established to: Facilitate the transfer of pragmatic KM methodologies and tools; Assist Member States considering implementation of nuclear power programmes to integrate KM in their management system from the very beginning; Provide specific consultancy services to address emergent problems and long term issues related to KM and associated issues; Assist organizations formulate detailed requirements and action plans related to KM; Help organizations identify, by self-assessment, their own KM maturity levels against a set of pre-defined criteria. This document is written to provide a common framework for KM missions and to provide general guidance for all mission participants. This document has been prepared to provide a basic structure and common reference for KM missions. As such, it is addressed, principally, to the team members of KM missions and also to the Counterpart requesting a mission. Although not mandatory, the guidelines provided in this document should be used as the basis for all future KM missions

  18. Hungarian experience in the role of a Technical Support Organization - Expert support and R and D activities in nuclear safeguards and forensics, participation in international cooperation

    International Nuclear Information System (INIS)

    Szeles, E.; Kovacs, A.; Biro, T.

    2010-01-01

    The Institute of Isotopes (IoI) of the Hungarian Academy of Sciences has been - since the mid-fifties - engaged not only in basic and applied research related to the use of radioisotopes in Hungary but also in the production, trade and safety of radioisotopes supported by the central accountancy at national level. Based on its experience and capabilities the technical tasks of nuclear safeguards and forensics have been delegated to the Institute by governmental decrees. Thus the Institute is one of the Technical Support Organizations of the Hungarian Atomic Energy Authority (HAEA) providing expert support in the areas mentioned above and maintaining the central isotope registry. An Agreement between HAEA and IoI specifies both routine and R and D activities supporting authority functions. These include the development and application of both non-destructive (i.e. gamma spectrometry, neutron-coincidence counting and laser ablation inductively coupled plasma mass spectrometry) and destructive (i.e. inductively coupled plasma mass spectrometry) analytical methods to satisfy domestic needs as well as to explore novel methods both for safeguards and nuclear forensics purposes. Methods have been developed to identify and quantify nuclear material in fresh and spent fuel assemblies and to characterize seized or found nuclear material of unknown origin and also environmental samples. The validation of these measurement methods have been performed in inter-laboratory comparisons organized by the Joint Research Centers of the European Union and by other international organizations such as IAEA and the International Technical Working Group on Nuclear Smuggling (ITWG). The presentation describes TSO activities both at domestic level and in potential international cooperation initiatives. The need of regional cooperation is emphasized discussing advantages and difficulties. (author)

  19. Aquatic indicator organisms as a tool to monitor discharges from nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Outola, Iisa; Vartti, Vesa-Pekka; Klemola, Seppo [STUK - Radiation and Nuclear Safety Authority, P.O. Box 14, 00881 Helsinki (Finland)

    2014-07-01

    There are four operating nuclear power plant units in Finland at two separate locations. The units started operation during 1977-1980. The surveillance of radioactive substances in the vicinities of the nuclear power plant is carried out under the permanent monitoring programs. Some 1000 samples are taken annually from the surroundings of the power plants to confirm that the discharges from the power plants are within permissible release limits and to monitor the dispersion of discharges in the environment. Aquatic indicator organisms (macro-algae, periphyton, mussels, crustacean, submerged aquatic plants) are included in the monitoring program. The indicator organisms are valuable monitoring objects both in normal and emergency situations because they accumulate effectively and often very rapidly radioactive substances from the medium. Six different species (Periphyton, Fucus vesiculosus, Myriophyllum spicatum, Potamogeton pectinatus, Saduria entomon, Macoma Baltica/Mytilus edulis) are collected regularly. Number of sampling location for each species varies from 1 to 7. Some species are collected continuously, some 1-2 times in a year. In this study we have evaluated the monitoring results for the aquatic indicator organisms for the period of 2005-2010 concerning concentration of discharge nuclides. Our aim was to answer the following questions using the monitoring data from aquatic organisms: 1) Which radionuclides are released to the marine environment and how often do we detect them? 2) How far from the nuclear power plants discharge radionuclides are detected? 3) How concentration of discharge radionuclides has changed with time in aquatic organisms? The number of discharge nuclides detected in the aquatic indicator samples was 11. Most of them were only detected in few samples, but {sup 58}Co, {sup 60}Co, {sup 54}Mn and {sup 110m}Ag were detected more frequently. Most of the observations above detection limits were made within the 5 km distance from the

  20. Spectrographic determination of metallic impurities in organic coolants for nuclear reactors; Determinacion espectrografica de impurezas metalicas en refrigerantes organicos para reactores nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Martin Munoz, M.; Alvarez Gonzalez, F.

    1969-07-01

    A spectrochemical method for determining metallic impurities in organic coolants for nuclear reactors is given. The organic matter in solid samples is eliminated by controlled distillation and dry ashing in the presence of magnesium oxide as carrier. Liquid, samples are vacuum distillated. The residue is analyzed by carrier distillation and by total burning techniques. The analytical results are discussed and compared with those obtained destroying the organic matter without carrier and using the copper spark technique. (Author) 12 refs.

  1. Resolution establishing the Preparatory Commission for the Comprehensive Nuclear Test-Ban Treaty Organization. Adopted on 19 November 1996

    International Nuclear Information System (INIS)

    1996-11-01

    The document reproduces the text of the Resolution on the Establishment of a Preparatory Commission for the Comprehensive Nuclear Test-Ban Treaty Organization which was adopted on 19 November 1996 at a meeting of the States Signatories of the Comprehensive Nuclear Test-Ban Treaty

  2. Idaho National Laboratory Ten-year Site Plan (2012 through 2021) -- DOE-NE's National Nuclear Capability -- Developing and Maintaining the INL Infrastructure

    Energy Technology Data Exchange (ETDEWEB)

    Cal Ozaki

    2010-06-01

    To meet long-term objectives to transform the Idaho National Laboratory (INL), we are providing an integrated, long-term vision of infrastructure requirements that support research, development and demonstration (RD&D) goals outlined in the DOE strategic plans, including the NE Roadmap and reports such as Facilities for the Future of Nuclear Energy Research: A Twenty-year Outlook. The goal of the INL Ten-year Site Plan (TYSP) is to clearly link RD&D mission goals and INL core capabilities with infrastructure requirements (single and multi-program), establish the 10-year end-state vision for INL complexes, identify and prioritize infrastructure and capability gaps, as well as the most efficient and economic approaches to closing those gaps.

  3. Whole-organism concentration ratios for plutonium in wildlife from past US nuclear research data

    International Nuclear Information System (INIS)

    Johansen, M.P.; Kamboj, S.; Kuhne, W.W.

    2013-01-01

    Whole-organism concentration ratios (CR wo-media ) for plutonium (Pu) in wildlife were calculated using data from the broad range of organism types and environmental settings of the US nuclear research program. Original sources included site-specific reports and scientific journal articles typically from 1960s to 80s research. Most of the calculated CR wo-media values are new to existing data sets, and, for some wildlife categories, serve to fill gaps or add to sparse data including those for terrestrial reptile; freshwater bird, crustacean and zooplankton; and marine crustacean and zooplankton. Ratios of Pu concentration in the whole-organism to that in specific tissues and organs are provided here for a range of freshwater and marine fish. The CR wo-media values in fish living in liquid discharge ponds were two orders of magnitude higher than those for similar species living in lakes receiving Pu from atmospheric fallout, suggesting the physico-chemical form of the source Pu can dominate over other factors related to transfer, such as organism size and feeding behavior. Small rodent data indicated one to two order of magnitude increases when carcass, pelt, and gastrointestinal tract were included together in the whole-organism calculation compared to that for carcass alone. Only 4% of Pu resided in the carcass of small rodents compared to 75% in the gastrointestinal tract and 21% in the pelt

  4. Role of Non-Government Organizations in strengthening Kazakstan nuclear export control

    International Nuclear Information System (INIS)

    Tazhibaeva, L.; Prokhodtseva, T.

    2002-01-01

    Non-governmental organizations (NGO) are the structures that were born by the time, the time when deep changes in our society led us to new trends in the all spheres of society development, to new decisions and, as a consequence, to new structural findings that where able to govern, to support and put into reality the new ideas the could not be inserted in the structure assemblies of the former society. All non-governmental organizations in Kazakhstan are younger than ten years old, but they already could be considered highly experienced, for intensity of their activity is rather high. The main advantages of NGOs are flexibility and independent source of ideas, basic data and policy assessment. There are several non-government organizations that are working in the field of non-proliferation and export control. Kazakhstan Nuclear Technology Safety Center (NTSC) is among them. Non-proliferation and export control is only a small part of activity that NTSC is involved in. Non-governmental organizations could be of several types: NGOs that are affiliated with university or institute, independent associations, quasi-governmental structures and various foundations. NTSC complementing efforts of Kazakhstan Atomic Energy Committee (KAEC) in the field of non-proliferation and export control. The activity of NTSC in the field of non-proliferation includes: Holding conferences, seminars and workshops; Creating databases and reports; Develop proposal for legislation; Provide specialized training; Analyze data. NTSC is involved in a number of projects devoted to non-proliferation and export control. The following projects are supported by the US Department of Energy cooperation program on nuclear export controls for Russia and the Newly Independent States: System to review Kazakhstan exports (STROKE); Computerization of historical licensing data; Export control reference materials for Kazakhstan organizations; Additional Protocol. STROKE is a technical analysis database for

  5. Understanding the Impacts and Meaning of Maintaining Detectable Disinfection Residuals in Drinking Water Distribution Systems: Controlling Waterborne Pathogens, Disinfection Byproducts, Organic Chloramines, and Nitrification

    Science.gov (United States)

    : EPA Region 6, in collaboration with the Office of Research and Development and Office of Water (OW) in Cincinnati, Ohio, and the Louisiana Department of Health and Hospitals (LDHH), proposes a drinking water research project to understand how maintaining various drinking water...

  6. To better know the biological behaviour of future nuclear materials: a need to maintain a good level of protection against ionising radiation

    International Nuclear Information System (INIS)

    Guillaumont, R.; Metivier, H.

    2007-01-01

    An important program of research, called 'Generation IV' is currently developed at an international level to prepare the launching of reactors for the future. Its objective is to satisfy the growing needs in electric power within the framework for a sustainable development. One of the major aspects of this program is the search and the development for new nuclear materials containing fissile/fertile isotopes. Unfortunately, one realizes today that for many compounds considered to be used to manufacture these materials, there are no radio-toxicologic data, allowing to the occupational physicist to evaluate the real risk in the event of contaminations and to prescribe adapted therapeutic de-corporation. An emergency revival of 'workplace' studies, where are or will be handled these compounds or materials is mandatory. The lesson of the past showed that the prevision in radioprotection was rather difficult and that an experimental validation of the behaviour of hazardous heavy elements both in vitro and in vivo was necessary. (authors)

  7. A position paper for a central procurement organization for the nuclear power industry

    International Nuclear Information System (INIS)

    Hendricks, J.R.

    1996-01-01

    This paper integrates the results of numerous nuclear utility industry meetings with commercial business practices. The Central Procurement Organization (CPO) is designed to achieve an immediate 30%--50% reduction in total procurement, engineering qualification, warehousing, and distribution cost. Three (3) areas define a CPO success criteria: (1) Lean, credible, and cost-effective issues discussed include facility cost, operational cost, staff expertise, product priorities, warehousing, and distribution, (2) Common technical, commercial, and quality requirement issues discussed include current industry practices and proposed future methodologies, and (3) Financial survivability issues which are the most critical since the CPO must exist during changing internal and external utility environments

  8. Modern techniques for the analysis of chromatin and nuclear organization in C. elegans.

    Science.gov (United States)

    Askjaer, Peter; Ercan, Sevinç; Meister, Peter

    2014-04-02

    In recent years, Caenorhabditis elegans has emerged as a new model to investigate the relationships between nuclear architecture, cellular differentiation, and organismal development. On one hand, C. elegans with its fixed lineage and transparent body is a great model organism to observe gene functions in vivo in specific cell types using microscopy. On the other hand, two different techniques have been applied in nematodes to identify binding sites for chromatin-associated proteins genome-wide: chromatin immunoprecipitation (ChIP), and Dam-mediated identification (DamID). We summarize here all three techniques together as they are complementary. We also highlight strengths and differences of the individual approaches.

  9. Preparedness of the operating organization (licensee) for emergencies at nuclear power plants

    International Nuclear Information System (INIS)

    1982-01-01

    This Guide outlines the principal elements in devising and implementing emergency plans so that actions to be taken in accordance with the plans ensure an orderly and timely decision-making process and the availability of essential personnel, equipment, supplies and services. Principal elements included in the Guide are: (1) An outline for the basis and content of emergency planning, and the activities to be covered; (2) The responsibilities and arrangements of the operating organization (licensee) in establishing and implementing the Operating Organization Emergency Plan; (3) The liaison between the operating organization (licensee), the regulatory body, and public authorities in relation to the Operating Organization Emergency Plan; (4) Detailed measures to protect persons on-site, and guidance with respect to protection of the public off-site; (5) Facilities and equipment to cope with the emergency situation; (6) Aspects relevant to maintaining the plan and the organization in operational readiness. Although this Guide does not consider emergencies related to the off-site transportation of radioactive materials or new or irradiated fuel, many of its recommendations may be useful in planning how to cope with such emergencies

  10. Material degradation of liquid organic semiconductors analyzed by nuclear magnetic resonance spectroscopy

    Directory of Open Access Journals (Sweden)

    Tatsuya Fukushima

    2015-08-01

    Full Text Available Liquid organic light-emitting diodes (liquid OLEDs are unique devices consisting only of liquid organic semiconductors in the active layer, and the device performances have been investigated recently. However, the device degradation, especially, the origin has been unknown. In this study, we show that material degradation occurs in liquid OLEDs, whose active layer is composed of carbazole with an ethylene glycol chain. Nuclear magnetic resonance (NMR experiments clearly exhibit that the dimerization reaction of carbazole moiety occurs in the liquid OLEDs during driving the devices. In contrast, cleavages of the ethylene glycol chain are not detected within experimental error. The dimerization reaction is considered to be related to the device degradation.

  11. A new approach for the calculation of critical organ dose in nuclear medicine applications

    International Nuclear Information System (INIS)

    Yasar, Dogan; Tugrul, A. Beril

    2005-01-01

    The geometrical factor that is calculated to keep in mind the radiation source and detector position is rather frequently used in radiation measuring and calculating methods. In this study, using the geometrical factor is intended to suggest a new model to measure the absorbed dose in nuclear medicine applications. Therefore, the source and target organ's geometries are accepted to be disc and parallel to each other. In this manner, a mathematical model for the geometry of these discs is proposed and a disc-disc geometry factor is calculated. Theoretical calculations have been carried out with the MIRD (medical internal absorbed dose) method, which is widely used to the absorbed dose calculations in nuclear medicine. Absorbed radiation dose is separately calculated for a target organ, which is the testis, with disc-disc geometry factor model and MIRD model. Both the results are compared and the results of disc-disc geometry factor model are shown to be harmonious and acceptable with the results of MIRD model

  12. IT–Enabled Knowledge Management System for Nuclear R&D Organization

    International Nuclear Information System (INIS)

    Jehadeesan, R.

    2016-01-01

    Full text: A knowledge management (KM) system for codification, preservation and utilization of all multi-disciplinary knowledge assets accumulated over several decades of nuclear research, development and operation is essential for improved organizational productivity, new insights and high-levels of innovation. IGCAR’s Nuclear Knowledge Management System deployed with IT-as-enabler addresses various challenges related to people, process, technology and resources and provides a technology platform to leverage the collective knowledge of the organization. This paper describes the strategic action plan and structured approach followed for building IT-enabled knowledge management system to acquire, store, share and utilize the organizational knowledge assets in the explicit form of publications, technical reports, presentations, projects, activities, facilities etc., along with the tacit knowledge multi-media modules. It highlights the salient features of the in-house-developed advanced KM portal deployed for facilitating the creation, archival, retrieval, sharing and dissemination of knowledge assets originating from diverse domains, in an organized and secured way. The paper also underlines the application of semantic technologies, tools and standards in implementing a robust KM technology infrastructure with enhanced functionalities. (author

  13. Nuclear Architecture Organized by Rif1 Underpins the Replication-Timing Program.

    Science.gov (United States)

    Foti, Rossana; Gnan, Stefano; Cornacchia, Daniela; Dileep, Vishnu; Bulut-Karslioglu, Aydan; Diehl, Sarah; Buness, Andreas; Klein, Felix A; Huber, Wolfgang; Johnstone, Ewan; Loos, Remco; Bertone, Paul; Gilbert, David M; Manke, Thomas; Jenuwein, Thomas; Buonomo, Sara C B

    2016-01-21

    DNA replication is temporally and spatially organized in all eukaryotes, yet the molecular control and biological function of the replication-timing program are unclear. Rif1 is required for normal genome-wide regulation of replication timing, but its molecular function is poorly understood. Here we show that in mouse embryonic stem cells, Rif1 coats late-replicating domains and, with Lamin B1, identifies most of the late-replicating genome. Rif1 is an essential determinant of replication timing of non-Lamin B1-bound late domains. We further demonstrate that Rif1 defines and restricts the interactions between replication-timing domains during the G1 phase, thereby revealing a function of Rif1 as organizer of nuclear architecture. Rif1 loss affects both number and replication-timing specificity of the interactions between replication-timing domains. In addition, during the S phase, Rif1 ensures that replication of interacting domains is temporally coordinated. In summary, our study identifies Rif1 as the molecular link between nuclear architecture and replication-timing establishment in mammals. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  14. Maintaining plant safety margins

    International Nuclear Information System (INIS)

    Bergeron, P.A.

    1989-01-01

    The Final Safety Analysis Report Forms the basis of demonstrating that the plant can operate safely and meet all applicable acceptance criteria. In order to assure that this continues through each operating cycle, the safety analysis is reexamined for each reload core. Operating limits are set for each reload core to assure that safety limits and applicable acceptance criteria are not exceeded for postulated events within the design basis. These operating limits form the basis for plant operation, providing barriers on various measurable parameters. The barriers are refereed to as limiting conditions for operation (LCO). The operating limits, being influenced by many factors, can change significantly from cycle to cycle. In order to be successful in demonstrating safe operation for each reload core (with adequate operating margin), it is necessary to continue to focus on ways to maintain/improve existing safety margins. Existing safety margins are a function of the plant type [boiling water reactor/pressurized water reactor (BWR/PWR)], nuclear system supply (NSSS) vendor, operating license date, core design features, plant design features, licensing history, and analytical methods used in the safety analysis. This paper summarizes the experience at Yankee Atomic Electric Company (YAEC) in its efforts to provide adequate operating margin for the plants that it supports

  15. Developing Sustainable Organizations for New Nuclear Power Countries through Knowledge Management

    International Nuclear Information System (INIS)

    Cain, R.; Kovacic, D.; Einwechter, M.; Reed, J.; Therios, I.

    2016-01-01

    Full text: Countries with emerging nuclear power programmes face unique challenges with respect to building competent and sustainable organizations. By nature, such organizations are dynamic and evolving, energetic, and feel a sense of mission. They are also typically preoccupied with near and mid-term objectives, may be resource–constrained, can incur high staff turnover rate, and encounter difficulties in obtaining experienced, qualified personnel. Such conditions can make it difficult to think about, much less implement, a knowledge management (KM)-based culture. The result can be missed opportunities if a KM system is not in place to collect institutional knowledge leveraged to advance the organization’s mission. Nevertheless, knowledge is perishable, and the best time to capture it is as it is being created, not at the end of a career. This paper explores some of the resource–efficient methods for knowledge capture applicable to programs/organizations early in their formation and which might be constrained in some way from instituting larger KM initiatives. The emphasis is on tools, techniques, and methods that integrate well with the day-to-day processes of the organization, reduce single points of failure, and transfer/preserve knowledge early in the lifecycle. (author

  16. Quantitative 3D Analysis of Nuclear Morphology and Heterochromatin Organization from Whole-Mount Plant Tissue Using NucleusJ.

    Science.gov (United States)

    Desset, Sophie; Poulet, Axel; Tatout, Christophe

    2018-01-01

    Image analysis is a classical way to study nuclear organization. While nuclear organization used to be investigated by colorimetric or fluorescent labeling of DNA or specific nuclear compartments, new methods in microscopy imaging now enable qualitative and quantitative analyses of chromatin pattern, and nuclear size and shape. Several procedures have been developed to prepare samples in order to collect 3D images for the analysis of spatial chromatin organization, but only few preserve the positional information of the cell within its tissue context. Here, we describe a whole mount tissue preparation procedure coupled to DNA staining using the PicoGreen ® intercalating agent suitable for image analysis of the nucleus in living and fixed tissues. 3D Image analysis is then performed using NucleusJ, an open source ImageJ plugin, which allows for quantifying variations in nuclear morphology such as nuclear volume, sphericity, elongation, and flatness as well as in heterochromatin content and position in respect to the nuclear periphery.

  17. Nuclear medicine in the monitoring of organ function and the detection of injury related to cancer therapy

    International Nuclear Information System (INIS)

    Valdes Olmos, R.A.; Hoefnagel, C.A.; Schoot, J.B. van der

    1993-01-01

    This article emphasizes the role of nuclear medicine in the monitoring of function to prevent or limit injury in organs in which toxicity related to cancer therapy may have implications for the survival and/or the quality of life of the patient. After a brief discussion of the advantages of nuclear medicine techniques in detecting organ injury, the effect of radiation therapy and chemotherapy on normal tissue is discussed, underlining the need to characterize adverse effects of cancer therapy in long-term survivors. The use of radionuclides to document organ injury and effects from cancer therapy in heart, digestive tract, kidneys, lungs major salivary glands skeleton and brain is then reviewed. In a short section the potential applicability of positron emission tomography in documenting organ toxicity during cancer therapy is discussed. Thanks to the various available radiopharmaceuticals, the ability of the tracers to document specific functional aspects, the improved methods for visualization and quantitation of organ injury and the possibilities of physiological or pharmacological intervention, nuclear medicine gives the clinician potent tools for the monitoring of organ function at risk during cancer therapy. The trend to intensify cancer treatment by combining various treatment modalities and the increasing chances of prolonged survival in a large number of patients call for effective integration of nuclear medicine methods into the recommended guidelines for grading organ injury in clinical oncology. (orig.)

  18. International conference on challenges faced by technical and scientific support organizations in enhancing nuclear safety. Contributed papers and presentations

    International Nuclear Information System (INIS)

    2007-01-01

    Over the past two decades, the IAEA has conducted a series of major conferences that have addressed topical issues and strategies critical to nuclear safety for consideration by the world's nuclear regulators. More recently, the IAEA organized the International Conference on Effective Nuclear Regulatory Systems - Facing Safety and Security Challenges, held in Moscow in 2006. The Moscow conference was the first of its kind, because it brought together senior regulators of nuclear safety, radiation safety and security from around the world to discuss how to improve regulatory effectiveness with the objective of improving the protection of the public and the users of nuclear and radioactive material. The International Conference on Challenges Faced by Technical and Scientific Support Organizations in Enhancing Nuclear Safety was held in Aix-en-Provence, France, from 23 to 27 April 2007. This conference, again, was the first of its kind, because it was the first to address technical and scientific support organizations (TSOs), the role they play in supporting either the national regulatory bodies or the industry in making optimum safety decisions and the challenges they face in providing this support. This conference provided a forum for the TSOs to discuss these and other issues with the organizations to which they provide this support - that is, the regulators and the operators/industry - as well as with other stakeholders such as research organizations and public authorities. This conference can also be considered to have a link to the Moscow conference. The Moscow conference concluded that effective regulation of nuclear safety is vital for the safe use of nuclear energy and associated technologies, both now and in the future, and is an essential prerequisite for establishing an effective Global Nuclear Safety Regime. The Moscow conference also highlighted the importance of continued and improved international cooperation in the area of nuclear safety. These

  19. Organizational aspects of recruiting, training, maintaining the level of professional skills and retraining of NPP operations personnel in Russia

    International Nuclear Information System (INIS)

    Veltchinsky, V.

    1993-01-01

    The organization of personnel work during WWER-1000 operation is presented as recommended by the Russian operating organization. The system is described of recruiting, training control of professional activities, maintaining of professional skills and retraining of the Russian nuclear power plant operation personnel (PKPO system). The basic documentation of the PKPO system is listed. (Z.S.) 1 fig

  20. Impact of nuclear organization and chromatin structure on DNA repair and genome stability

    International Nuclear Information System (INIS)

    Batte, Amandine

    2016-01-01

    The non-random organization of the eukaryotic cell nucleus and the folding of genome in chromatin more or less condensed can influence many functions related to DNA metabolism, including genome stability. Double-strand breaks (DSBs) are the most deleterious DNA damages for the cells. To preserve genome integrity, eukaryotic cells thus developed DSB repair mechanisms conserved from yeast to human, among which homologous recombination (HR) that uses an intact homologous sequence to repair a broken chromosome. HR can be separated in two sub-pathways: Gene Conversion (GC) transfers genetic information from one molecule to its homologous and Break Induced Replication (BIR) establishes a replication fork than can proceed until the chromosome end. My doctorate work was focused on the contribution of the chromatin context and 3D genome organization on DSB repair. In S. cerevisiae, nuclear organization and heterochromatin spreading at sub-telomeres can be modified through the overexpression of the Sir3 or sir3A2Q mutant proteins. We demonstrated that reducing the physical distance between homologous sequences increased GC rates, reinforcing the notion that homology search is a limiting step for recombination. We also showed that hetero-chromatinization of DSB site fine-tunes DSB resection, limiting the loss of the DSB ends required to perform homology search and complete HR. Finally, we noticed that the presence of heterochromatin at the donor locus decreased both GC and BIR efficiencies, probably by affecting strand invasion. This work highlights new regulatory pathways of DNA repair. (author) [fr

  1. International ITER fusion energy organization. Paving the way to power generation from nuclear fusion

    International Nuclear Information System (INIS)

    Preuschen-Liebenstein, R. von

    2006-01-01

    ITER (Latin: the way) is the acronym of a new international large research facility gradually taking shape after the meeting of Gorbachev and Reagan in Reykjavik in 1985. Under the auspices of the IAEA, worldwide scientific and industrial cooperation with 'home teams' of each of the ITER partners began at that time which were commissioned to accumulate the knowledge and the technology of nuclear fusion in the participating countries. At the end of the preparation and decisionmaking process, the design draft of the ITER reactor was elaborated in international cooperation as the basis of the ITER Convention. After lengthy negotiations among the international ITER partners, a European site for the ITER organization and its reactor was found at Cadarache, France. As the first ITER member, Europe now initiated worldwide cooperation in research and development, seeking to demonstrate the technical and scientific feasibility of tapping fusion power for peaceful purposes. The Council of the European Union (competitiveness), at its meeting on September 25, 2006, decided to sign the ITER Convention about the establishment of the International ITER Fusion Energy Organization ('ITER Organization') and about the mutual obligation to make the necessary contributions towards the construction of ITER. (orig.)

  2. A Condition Analysis for Advancing Exalted Level of Nuclear International Organization

    Energy Technology Data Exchange (ETDEWEB)

    Kim, H. J.; Oh, K. B.; Chung, W. S.; Lee, K. S.; Yun, S. W.; Jeong, I.; Ko, H. S.; Lee, J. H

    2008-02-15

    This paper aimed at developing the strategy for facilitating the Korean participation as a higher staff in the nuclear related international organizations. - For that purpose, this Study focused on the following three subjects ; (1) to analyze the job situation of international organizations, (2) to analyze the background information and the procedure of appointment, (3) to suggest a facilitating strategy. - There are over 40 higher staff members including Director-General, six Deputy Director-General and 36 Directors in IAEA. Analysis shows that there are three main factors which influence the appointment of those higher position; geographical distribution, members' contributions towards the regular budget and a nation's influencing power to the international community. We can categorize into two case in aspect of the agency's appointment procedure. A director's position is generally decided through the open competition. In the case of Deputy Director-General or higher position, however, it is a practice that the Agency appoints the candidates through a unofficial procedure considering political situation. - There are twelve higher staffs in NEA. Influencing power and members' contributions towards the regular budget are the major criteria of higher staff's appointment. - It is expected that this study will contribute to the facilitation of Korean participation as a higher staff in the international organization by supplying the basic strategy.

  3. Transforming the organization - a systems approach: One nuclear power plant's journey

    International Nuclear Information System (INIS)

    Ashbridge, G.A.

    2002-01-01

    Change management continues to be an imperative for organizational leaders as they move into the 21st century; globalization, hyper-competition, advanced technology, employee expectations and a changing workforce significantly impact the way in which organizations operate. Unfortunately up to 75% of change initiatives fail. Nuclear power plants in the United States face the same challenges as manufacturing and industrial firms with the added challenge of deregulation. Faced with these new business realities, restructuring the electric utility has raised a number of complex issues. Under traditional cost-of-service regulation, electric utilities were able to pass their costs on to consumers who absorbed them. In the new competitive environment, customers can now choose their suppliers based on the most competitive price, quality and efficiency of service. The purpose of this study was to determine the degree of congruence between non-supervisory and supervisory personnel regarding the perceived implementation levels of high performance workplace practices at a nuclear power plant. In today's business environment it is those plants that can demonstrate integrated and aligned high performance workplace practices that will survive a deregulated and competitive market. The population for this study consisted of organizational members at one nuclear power plant. Over 300 individuals completed surveys on high performance workplace practices. Two surveys were administered, one to non-supervisory personnel and one to first line supervisors and above. The determination of perceived implementation levels of the high performance workplace practices identified was accomplished through descriptive statistical analysis. Results of the study revealed 32 areas of non-congruence between non-supervisory and supervisory personnel. Factor analysis further revealed the order in which the respondents place emphasis on the variables differs between the two groups. This study provided

  4. Study of the stability of organic ligands usable for the spent nuclear fuel reprocessing

    International Nuclear Information System (INIS)

    Draye, Micheline

    1994-01-01

    The first part of this research thesis on the stability of organic ligands in radioactive environment, reports the study of the stability of the dicyclohexano-18-crown-6 (DCH18C6) in radioactive environment by using several analytical techniques (nuclear magnetic resonance or NMR, X-ray diffraction, Fourier transform infrared spectroscopy or FTIR, gas chromatography or GC, and coupled gas chromatography/mass spectroscopy). The seven main radiolysis products of DCH18C6 are identified and then synthesised to be tested in radioactive environment. These products are soluble in nitric medium, and partially precipitate plutonium, but cannot in any case disturb the reprocessing process based on a continuous extraction system. Chemical yields are computed and DCH18C6 appears to be a serious candidate for the reprocessing of spent nuclear fuels. The second part reports the study of the stability of the poly(4-vinylpyridine) or P4VP in radioactive environment. It appears that gamma radiations produce radicals in the P4VP which recombine in function of the irradiation dose. However, this material is very stable in acid environment and radioactive environment [fr

  5. Nuclear weapons decision-making; an application of organization theory to the mini-nuke case

    International Nuclear Information System (INIS)

    Kangas, J.L.

    1985-01-01

    This dissertation addresses the problem of constructing and developing normative theory responsive to the need for improving the quality of decision-making in the nuclear weapons policy-making. Against the background of a critical evaluation of various paradigms in the literature (systems analysis and opposed-systems designed, the bureaucratic politics model, and the cybernetic theory of decision) an attempt is made to design an alternative analytic framework based on the writings of numerous organization theorists such as Herbert Simon and Kenneth Arrow. The framework is applied to the case of mini-nukes, i.e., proposals in the mid-1970s to develop and deploy tens of thousands of very low-yield (sub-kiloton), miniaturized fission weapons in NATO. Heuristic case study identifies the type of study undertaken in the dissertation in contrast to the more familiar paradigmatic studies identified, for example, with the Harvard Weapons Project. Application of the analytic framework developed in the dissertation of the mini-nuke case resulted in an empirical understanding of why decision making concerning tactical nuclear weapons has been such a complex task and why force modernization issues in particular have been so controversial and lacking in policy resolution

  6. Behaviour of the radioactive noxious substances of nuclear industry in the organism

    International Nuclear Information System (INIS)

    Seidel, A.

    1977-01-01

    In the present publication, the behaviour of important radionuclides, occuring in nuclear industry, is described. An understanding of their behaviour, whose phenomena generally are well known, is a prerequisite for understanding the principles of radiation protection measures as well as a base for a discussion of the biological effects of radionuclides, which, however, are not described in this paper. The biological behaviour is characterized by the ways of resorption of the nuclides, their distribution and retention in the organs and their excretion pattern. An essential question is concerned with differences between animal species and with the extrapolation of animal data to man. The behaviour of some of the radionuclides in man is already well known; in the other cases, typical data from animal experiments will be given in order to characterize the biological behaviour. (orig.) [de

  7. Imaging Nuclear Morphology and Organization in Cleared Plant Tissues Treated with Cell Cycle Inhibitors.

    Science.gov (United States)

    de Souza Junior, José Dijair Antonino; de Sa, Maria Fatima Grossi; Engler, Gilbert; Engler, Janice de Almeida

    2016-01-01

    Synchronization of root cells through chemical treatment can generate a large number of cells blocked in specific cell cycle phases. In plants, this approach can be employed for cell suspension cultures and plant seedlings. To identify plant cells in the course of the cell cycle, especially during mitosis in meristematic tissues, chemical inhibitors can be used to block cell cycle progression. Herein, we present a simplified and easy-to-apply protocol to visualize mitotic figures, nuclei morphology, and organization in whole Arabidopsis root apexes. The procedure is based on tissue clearing, and fluorescent staining of nuclear DNA with DAPI. The protocol allows carrying out bulk analysis of nuclei and cell cycle phases in root cells and will be valuable to investigate mutants like overexpressing lines of genes disturbing the plant cell cycle.

  8. Integrative modeling reveals the principles of multi-scale chromatin boundary formation in human nuclear organization.

    Science.gov (United States)

    Moore, Benjamin L; Aitken, Stuart; Semple, Colin A

    2015-05-27

    Interphase chromosomes adopt a hierarchical structure, and recent data have characterized their chromatin organization at very different scales, from sub-genic regions associated with DNA-binding proteins at the order of tens or hundreds of bases, through larger regions with active or repressed chromatin states, up to multi-megabase-scale domains associated with nuclear positioning, replication timing and other qualities. However, we have lacked detailed, quantitative models to understand the interactions between these different strata. Here we collate large collections of matched locus-level chromatin features and Hi-C interaction data, representing higher-order organization, across three human cell types. We use quantitative modeling approaches to assess whether locus-level features are sufficient to explain higher-order structure, and identify the most influential underlying features. We identify structurally variable domains between cell types and examine the underlying features to discover a general association with cell-type-specific enhancer activity. We also identify the most prominent features marking the boundaries of two types of higher-order domains at different scales: topologically associating domains and nuclear compartments. We find parallel enrichments of particular chromatin features for both types, including features associated with active promoters and the architectural proteins CTCF and YY1. We show that integrative modeling of large chromatin dataset collections using random forests can generate useful insights into chromosome structure. The models produced recapitulate known biological features of the cell types involved, allow exploration of the antecedents of higher-order structures and generate testable hypotheses for further experimental studies.

  9. Composition and structure of natural organic matter through advanced nuclear magnetic resonance techniques

    Directory of Open Access Journals (Sweden)

    Dainan Zhang

    2017-02-01

    Full Text Available Abstract Natural organic matter (NOM plays important roles in biological, chemical, and physical processes within the terrestrial and aquatic ecosystem. Despite its importance, a clear and exhaustive knowledge on NOM chemistry still lacks. Aiming to prove that advanced solid-state 13C nuclear magnetic resonance (NMR techniques may contribute to fill such a gap, in this paper we reported relevant examples of its applicability to NOM components, such as biomass, deposition material, sediments, and kerogen samples. It is found that nonhydrolyzable organic carbons (NHC, chars, and polymethylene carbons are important in the investigated samples. The structure of each of the NHC fractions is similar to that of kerogens, highlighting the importance of selective preservation of NOM to the kerogen origin in the investigated aquatic ecosystems. Moreover, during the artificial maturation experiments of kerogen, the chemical and structural characteristics such as protonated aromatic, nonprotonated carbons, and aromatic cluster size play important roles in the origin and variation of nanoporosity during kerogen maturation. Graphical abstract NMR parameters of thermally stimulated kerogens

  10. Planning, managing and organizing the decommissioning of nuclear facilities: Lessons learned

    International Nuclear Information System (INIS)

    2004-05-01

    This publication is intended to encourage the development and improvement of decommissioning planning and management techniques, with the focus on organizational aspects, reduce the duplication of efforts by different parties by transfer of experience and know-how, and provide useful results for those Member States planning or implementing decommissioning projects. In general it can be stated that any decommissioning project can be completed without any deleterious effects on the safety of the workforce and the public or any identifiable impact on the environment. However, timeliness and cost-effectiveness are not always optimal. It has been noted on several occasions that the major weakness in decommissioning projects (as well as in other industrial projects) is often not the lack of technologies, but rather poor planning and management. This publication intends to stimulate awareness of the need for early and efficient planning and to foster developments in management and organization in association with planned or ongoing decommissioning projects. A companion report on Organization and Management for Decommissioning of Large Nuclear Facilities was published by the IAEA in 2000 (Technical Report Series (TRS) No. 399). That TRS provides generic guidance on organizational and management aspects. This TECDOC is complementary to the existing report in that it highlights practical experience - in particular, typical issues, evidence of poor management, undue delays, and lack of timely funding - and distils lessons learned from this experience

  11. Organization of public authorities in France for the event of an incident or accident involving nuclear safety: Simulation of a nuclear crisis

    International Nuclear Information System (INIS)

    Cartigny, J.; Majorel, Y.

    1986-01-01

    The French nuclear safety regulations lay down the action to be taken in the event of an incident or accident involving the types of radiological hazard that could arise in a nuclear installation or during the transport of radioactive material. The organization established for this purpose is designed to ensure that the technical measures taken by the authorities responsible for nuclear safety, radiation protection, public order and public safety are fully effective. The Interministerial Nuclear Safety Committee (Comite interministeriel de la securite nucleaire), which reports to the Prime Minister, co-ordinates the measures taken by the public authorities. The public authorities and the operators together organize exercises designed to verify the whole complex of measures foreseen in the event of an incident or accident. These exercises, which have been carried out in a systematic manner in France for some years, are based on scenarios which are as realistic as possible and enable the following objectives to be achieved: (1) analysis of the crisis apparatus (ORSECRAD plans, individual intervention plans, information conventions); (2) uncovering gaps or inadequacies; (3) arrangements for interchange of information between the various participants whose responsibilities involve them in the emergency; and (4) allowance for the information requirements of the media and the population. The information drawn from these exercises enables the various procedures to be improved step by step. (author)

  12. Organizations` Responsibility in Maintaining the Security of Personal Data posted Online by Romanian Consumers: an Exploratory Analysis of Facebook and Linkedin

    Directory of Open Access Journals (Sweden)

    Andreea Ionescu

    2014-02-01

    Full Text Available Despite increased consumer concern about the privacy threat posed by new technologies and the Internet as a whole, there is relatively little evidence that people’s privacy concerns actually translate into privacy-enhancing behaviors while online. One can say that it is not yet well understood how privacy concerns and trust influence social interactions between consumers within social networking sites. That is why, this article presents an exploratory study of perceptions of trust and privacy concern, along with willingness to share information and develop new relationships within two of the most popular social networking sites in Romania, Facebook and LinkedIn. The research shows that organizations must assume greater responsibility in ensuring consumers’ safety who sometime neglect protecting their personal information, otherwise confidential. In this respect, the application of ISO 26000 standard recommendations by organizations would allow them to pass from just good intentions towards consumers to good actions, so that they are truly protected. The information was gathered with the help of an online questionnaire, administered to people over 18 years old. It is a very useful and needed tool for Romanian companies, as it presents the users’ point of view, allowing them to find the best and most ethical way to do social data mining or use consumers’ private information, disclosed on such sites. It is our strong belief that sometimes companies have to play an active part in helping users protect themselves from actually disclosing too much personal information on social networking sites. The paper begins with a summary of relevant research related to social networking sites. Then, the online survey methodology is described and the results presented, followed by limitations and conclusions.

  13. The role of a multiagent organization in the management of nuclear plants operational objectives

    International Nuclear Information System (INIS)

    Papin, B.; Arnaud, G.; Fiche, Ch.; Dumas, M.

    1998-01-01

    The aim of the ESCRIME project, now reaching conclusions, was to optimize the collaboration between plant operators and computerized systems for the management of plant safety and availability. The requirement for putting such a collaboration into effective application was to clarify the operational strategies in order to enable a dialog between men and systems based on a ''shared representation'' of the plant operation. Thus a new vision of this operation, focusing on the completion of the plant fundamental objectives has been defined. This so-called means-ends strategy enables the simultaneous management of these objectives and provides explicit rules (priority...) to solve eventual conflicts (Physical interaction, sharing of resources...) apt to occur. The direct implementation of such strategies by the operators, using a dedicated man/machine interface, has made the object of the second phase of the ESCRIME project, already presented in LOEN in 1996. The third phase of the program, more prospective, aimed at finding an efficient way of sharing the management of plant objectives between the operator(s) and ''intelligent controllers'', preserving the role of the man in the decision loop and enabling him to maintain his awareness about the evolution of the plant. The multiagent organization has been identified as a promising way of sharing executive and decisive tasks between human and computerized agents. This organization, based on explicit ''social'' rules managing the negotiation between autonomous agents, appeared quite perfectly adapted to the management of conflicting objectives like in the means - ends strategy. The main problem to solve was, in fact, to check whether humans could be brought under this social organization in such a way as they could communicate and negotiate efficiently with the computerized agents. After a brief recall of the principles of the means - ends strategy for plant objectives management, this paper will detail the work made on

  14. Project for export system construction of nuclear equipment to IAEA; survey on current market status of the nuclear related international organizations and the domestic possible suppliers

    Energy Technology Data Exchange (ETDEWEB)

    Min, T. S.; Cho, H. K.; Kim, H. J. [Korea Atomic Industrial Forum, Seoul (Korea)

    2001-05-01

    Republic of Korea are keeping the dynamic activities in IAEA as the 8th advanced nuclear country over the world but has occupied very low late less than 0.01% in supplying the equipments to IAEA. About 6,000 nuclear equipment suppliers are registered in IAEA Supply Roster over the world but only 3 Suppliers of our country are registered in IAEA Supply Roster. The supply of nuclear industrial products equivalent to about 100 million dollars into IAEA market will endorse not only the international authorization for our technology and products but also give contribution to activate the domestic nuclear industries in order to increase its expert. The explanation for IAEA procurement market to the 53 nuclear companies will be made on May 16, 2001, and the participants for the export of their goods will be selected. And then we will do all possible supports by the government and related organizations for them to register in IAEA Supply Roster. 21 refs. (Author)

  15. Maintaining ancient organelles: mitochondrial biogenesis and maturation.

    Science.gov (United States)

    Vega, Rick B; Horton, Julie L; Kelly, Daniel P

    2015-05-22

    The ultrastructure of the cardiac myocyte is remarkable for the high density of mitochondria tightly packed between sarcomeres. This structural organization is designed to provide energy in the form of ATP to fuel normal pump function of the heart. A complex system comprised of regulatory factors and energy metabolic machinery, encoded by both mitochondrial and nuclear genomes, is required for the coordinate control of cardiac mitochondrial biogenesis, maturation, and high-capacity function. This process involves the action of a transcriptional regulatory network that builds and maintains the mitochondrial genome and drives the expression of the energy transduction machinery. This finely tuned system is responsive to developmental and physiological cues, as well as changes in fuel substrate availability. Deficiency of components critical for mitochondrial energy production frequently manifests as a cardiomyopathic phenotype, underscoring the requirement to maintain high respiration rates in the heart. Although a precise causative role is not clear, there is increasing evidence that perturbations in this regulatory system occur in the hypertrophied and failing heart. This review summarizes current knowledge and highlights recent advances in our understanding of the transcriptional regulatory factors and signaling networks that serve to regulate mitochondrial biogenesis and function in the mammalian heart. © 2015 American Heart Association, Inc.

  16. Organization and execution of nondestructive examination recheck on important items during installation stage of nuclear power plants

    International Nuclear Information System (INIS)

    Cao feng; Gao Fei; Fang Jiang; Zhao Lei; Ding Youyuan; Wang Jianjun

    2013-01-01

    During nuclear power plant equipment manufacture and installation stage, welding quality is tightly relevant to nuclear safety and economy. In order to prevent common-mode defects induced by weld materials, pipes and welding procedures being brought into operation, nondestructive examination (NDE) recheck on important items had be carried out firstly during installation by Qinshan Phase-II Expansion Project. Considering the importance of NDE-recheck, this article introduced the organization and selection principles of NDE-recheck, described the range, methods and optimization principles of important welding inside nuclear island (include nuclear auxiliary pipe welding and pools welding with stainless steel cover) and important equipment inside conventional island (related to shut-down or heat-exchange efficiency), and summarized the NDE-recheck results and well-known experiences. (authors)

  17. A preliminary study on the cultural differences between Korean and Japanese organizations in nuclear power plants

    International Nuclear Information System (INIS)

    Lee, Yong Hee; Lee, Yong Hee; Oh, Ingyu; Do, Giang

    2012-01-01

    The meltdowns of the Chernobyl and Fukushima I nuclear reactors are fundamentally linked to their organizational characteristics, as they caused severe social and economic disruptions with equally significant environmental and health related impacts. This shows that we have to find practical solutions to reactor safety from various organizational standpoints by introducing a systematic approach to the issue of organizational deficiencies and human errors. We posit that one of the fundamental causes of organizational deficiencies can be derived from an organizational culture. An organizational culture has both formal and informal types. Generally, organizational culture refers to the common beliefs, values, norms, symbols, and language systems that organizational members use when they add meaning to their organizational behavior within their specific organizations. The purpose of this study is threefold. First, we are interested in finding internal contradictions between Korean organizational culture and U.S.-derived organizational safety mechanisms applied to the operation of Korean NPPs (Nuclear Power Plants). We want to discern safety related problems that are thought to have occurred routinely within the parameters of Korean NPPs owing to the use of U.S. safety mechanisms. Second, we compare the Korean and Japanese organizational culture in NPP mainly on safety and comfort cultures in order to cope with the cultural problems. Third, we want to propose an alternative model of safety mechanisms that are more appropriate for Korean organizational culture, using a system dynamic model that we devised based on empirical observations from the NPPs and factors drawn from the extant literature as compared with Japanese organizational culture

  18. Experiences on reduction of reactor water silica and fresh resin leaching organics for Kuo-Sheng Nuclear Power Plant

    International Nuclear Information System (INIS)

    Wen, T-J.; Wang, C-H.

    2010-01-01

    The silica level in reactor water of Kuo-Sheng nuclear power plants has been slowly increased from 200 ppb to the high level above 500 ppb in recent years. The results obtained from steam/liquid mass balance calculation indicated that an increase of reactor water silica was mainly caused by continuing equilibrium leakage from deep bed condensate demineralizers, where the ion exchange zone was periodically disturbed by resin backwashing - scrubbing operation. The fastest and the most effective way to reduce the silica inventory in reactor system is to operate by continuously precoating of two sets of the reactor water clean up filter demineralizers to a lower effluent silica end point, and perhaps as frequently as three or four days. Leaching organic contaminants into feed water from the ion exchange resin becomes a key greater problem of current concern for the stable water quality promotion of condensate demineralizer. The presence of those impurities have practically been difficult to analyze by simple quality testing of the resin, and may result in as much as a hundred fold increase in chloride and sulfate in reactor water. As resin displacement with high leachable TOC, a repeated continuous soaking and effectively rinsing is required so that steady state TOC content less than 150 ppb should be achieved in an acceptably short period of time before put in-service. It is clear that cation resin containing high leachables generates high level of sulfates and sometimes also gives unexpected level of chlorides. The current TOC limits in condensate demineralizer effluent with 0.1 ppb become a significant experience to maintain reactor water soluble impurity in low levels. New resin should be subjected to TOC quality control testing prior to acceptance especially when first placed into service. TOC and organic chloride leachables for as-received virgin cation resin that are to be used in condensate polisher should be limited to be less than 100 mg-TOC and 0.5 mg-Cl per

  19. The function of specialized organization in work safety engineering for nuclear installations

    International Nuclear Information System (INIS)

    Salvatore, J.E.L.

    1989-01-01

    The attributions of Brazilian CNEN in the licensing procedures of any nuclear installation are discussed. It is shown that the work safety engineering and industrial safety constitute important functions for nuclear safety. (M.C.K.) [pt

  20. Draft Law on the creation, attribution, organization and functioning of a ''Regulatory Authority and Nuclear Safety'' (ARSN)

    International Nuclear Information System (INIS)

    Issoufou, Mahamadou

    2016-08-01

    This Draft Law deals with the establishment, responsibilities, organization and functioning of an Autority Control and Nuclear Safety. Through this law, the Regulatory and Nuclear Safety Autority is responsible for regulation of nuclear and radiological activities to ensure the safety, security and protection of persons and the environment against the effects of radiation throughout the national territory. [fr

  1. Draft Revised Agreement Between the Government of the French Republic and the European Organization for Nuclear Research concerning the Legal Status of the Said Organization in France - Changes to be made to the English and French Texts of the Draft

    CERN Document Server

    1972-01-01

    Draft Revised Agreement Between the Government of the French Republic and the European Organization for Nuclear Research concerning the Legal Status of the Said Organization in France - Changes to be made to the English and French Texts of the Draft

  2. Studies on the effectiveness of measures to maintain the integrity of pressurized components in German nuclear power plants. Final report; Untersuchungen zur Wirksamkeit von Massnahmen zur Sicherstellung der Integritaet druckfuehrender Komponenten in deutschen Kernkraftwerken. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Elmas, M.; Jendrich, U.; Michel, F.; Reck, H.; Schimpfke, T.; Walter, M.; Wenke, R.

    2013-03-15

    The overall objective of the project was to investigate the effectiveness of measures to maintain the as-built quality of the pressure-retaining components in German nuclear power plants. In particular, investigations were performed on the application of the break preclusion concept, existing monitoring systems and the significance of the pressure test as part of the inspection concept. Moreover, the KompInt knowledge base has been updated. Break preclusion for pipes was applied in all German plants already during planning or after commissioning to a varying extent. The basic features of the required assessments were considered in the German nuclear regulations for the first time by inclusion in the safety requirements for nuclear power plants of 2012. The requirements for assessments, differing in their degree of detail, in the interpretations of these safety requirements and in the safety standard KTA 3206 are still in the draft stage. For the first time, the vessels as well as housings of valves and pumps are also included in the concept. Through the use of advanced monitoring systems it was possible in German plants at an early stage to establish modes of operation that minimise the load on components, to carry out appropriate technical backfitting measures, and to identify damages. In plant areas where local water chemistry parameters may result that deviate from the specification, the effectiveness of water chemistry monitoring is limited. In this case, other operational measures must be taken. The results of the simulations performed with the help of the GRS-developed PROST computer code to determine the significance of pressure tests lead - in accordance with the results of operating experience evaluation - to the conclusion that pressure tests carried out within the pressure-retaining boundary contribute to safeguarding the integrity. The user-friendliness of the KompInt knowledge base has been increased by changing over to a new hardware, a software

  3. Approaching the sequential and three-dimensional organization of Archaea, Bacteria and Eukarya genomes. Dynamic Organization of Nuclear Function

    NARCIS (Netherlands)

    T.A. Knoch (Tobias); M. Göker (Markus); R. Lohner (Rudolf); J. Langowski (Jörg)

    2002-01-01

    textabstractThe largely unresolved sequential organization, i.e. the relations within DNA sequences, and its connection to the three-dimensional organization of genomes was investigated by correlation analyses of completely sequenced chromosomes from Viroids, Archaea, Bacteria, Arabidopsis

  4. Invisible nuclear; converting nuclear

    International Nuclear Information System (INIS)

    Park, Jongmoon

    1993-03-01

    This book consists of 14 chapters which are CNN era and big science, from East and West to North and South, illusory nuclear strategy, UN and nuclear arms reduction, management of armaments, advent of petroleum period, the track of nuclear power generation, view of energy, internationalization of environment, the war over water in the Middle East, influence of radiation and an isotope technology transfer and transfer armament into civilian industry, the end of nuclear period and the nuclear Nonproliferation, national scientific and technological power and political organ and executive organ.

  5. Warning and reporting at radioactive fallout from nuclear weapons organization in war. Foundation in peace. Varning och rapportering vid radioaktivt nedfall fran kaernvapen. krigsorganisation pa fredens grund

    Energy Technology Data Exchange (ETDEWEB)

    Ulvsand, T.; Larsson, T.; Persson, G.; Edvarson, K.; Finck, R.

    1994-03-01

    This report discusses with the question of how to form a new radiation protection organization for Sweden in the event of nuclear war. The foundation for this is the peacetime preparedness against nuclear power plant accidents. The contents concentrate on the responsibility as well as the tasks for the different organization levels and the resources needed.

  6. Exposing exposure: enhancing patient safety through automated data mining of nuclear medicine reports for quality assurance and organ dose monitoring.

    Science.gov (United States)

    Ikuta, Ichiro; Sodickson, Aaron; Wasser, Elliot J; Warden, Graham I; Gerbaudo, Victor H; Khorasani, Ramin

    2012-08-01

    To develop and validate an open-source informatics toolkit capable of creating a radiation exposure data repository from existing nuclear medicine report archives and to demonstrate potential applications of such data for quality assurance and longitudinal patient-specific radiation dose monitoring. This study was institutional review board approved and HIPAA compliant. Informed consent was waived. An open-source toolkit designed to automate the extraction of data on radiopharmaceuticals and administered activities from nuclear medicine reports was developed. After iterative code training, manual validation was performed on 2359 nuclear medicine reports randomly selected from September 17, 1985, to February 28, 2011. Recall (sensitivity) and precision (positive predictive value) were calculated with 95% binomial confidence intervals. From the resultant institutional data repository, examples of usage in quality assurance efforts and patient-specific longitudinal radiation dose monitoring obtained by calculating organ doses from the administered activity and radiopharmaceutical of each examination were provided. Validation statistics yielded a combined recall of 97.6% ± 0.7 (95% confidence interval) and precision of 98.7% ± 0.5. Histograms of administered activity for fluorine 18 fluorodeoxyglucose and iodine 131 sodium iodide were generated. An organ dose heatmap which displays a sample patient's dose accumulation from multiple nuclear medicine examinations was created. Large-scale repositories of radiation exposure data can be extracted from institutional nuclear medicine report archives with high recall and precision. Such repositories enable new approaches in radiation exposure patient safety initiatives and patient-specific radiation dose monitoring.

  7. A possible biomedical facility at the European Organization for Nuclear Research (CERN).

    Science.gov (United States)

    Dosanjh, M; Jones, B; Myers, S

    2013-05-01

    A well-attended meeting, called "Brainstorming discussion for a possible biomedical facility at CERN", was held by the European Organization for Nuclear Research (CERN) at the European Laboratory for Particle Physics on 25 June 2012. This was concerned with adapting an existing, but little used, 78-m circumference CERN synchrotron to deliver a wide range of ion species, preferably from protons to at least neon ions, with beam specifications that match existing clinical facilities. The potential extensive research portfolio discussed included beam ballistics in humanoid phantoms, advanced dosimetry, remote imaging techniques and technical developments in beam delivery, including gantry design. In addition, a modern laboratory for biomedical characterisation of these beams would allow important radiobiological studies, such as relative biological effectiveness, in a dedicated facility with standardisation of experimental conditions and biological end points. A control photon and electron beam would be required nearby for relative biological effectiveness comparisons. Research beam time availability would far exceed that at other facilities throughout the world. This would allow more rapid progress in several biomedical areas, such as in charged hadron therapy of cancer, radioisotope production and radioprotection. The ethos of CERN, in terms of open access, peer-reviewed projects and governance has been so successful for High Energy Physics that application of the same to biomedicine would attract high-quality research, with possible contributions from Europe and beyond, along with potential new funding streams.

  8. Nuclear power plant organization and staffing for improved performance: Lessons learned

    International Nuclear Information System (INIS)

    1998-11-01

    Experience from well operated nuclear power plants (NPPs) around the world indicates that an organizational structure which efficiently supports plant operation is essential in economically achieving both high level of safety and operational performance. At the same time energy markets are being opened to competition in many Member States. It is in consideration of this new competitive energy market that the overall objective of this document is to provide NPP managers information on lessons learned on improving the organization and staffing of NPP activities. Within this overall objective, specific objectives are to: Identify organisational design and staffing principles, Provide examples of how NPPs implement these principles, Identify typical NPP staffing levels, Factors affecting these levels, and staffing trends among various NPP types. Although it is not expected that any particular utility or NPP manager would consider all of the suggestions provided here to be appropriate, it is anticipated that nearly every NPP manager in IAEA Member States would find some ideas useful in improving the efficiency and effectiveness of NPP activities

  9. Acquisition Of Organ Slice Images In Nuclear Medicine By The Multiple-Incidence Technique

    Science.gov (United States)

    Danet, B.; Hatzigiannaki, A.; Percheron, M.; Morucci, J. P.; Guiraud, R.

    1983-08-01

    In the development of devices to represent the three-dimensional structure of radio-activated organs, Nuclear Medicine has been following the progress in Radiology. That parallelism could be observed with all principles used to get three-dimensional data : - analogical systems working by simultaneous displacement of the detector and the object, - coded-aperture imaging devices which consist of special collimators designed to obtain a dependance between the object-to-code distance and the detector response, - multiple-incidence techniques, the 3D reconstruction being extracted from the whole set of projections of the object at different orientations. That last principle was chosen in the studies that we are working on now. It is close to the principle used in Radio-Tomo-densitometry : a detector gets a set of projections as it turns around the object. From these projections, the classical reconstruction algorithms can be used : ART, SIRT, Convolution algorithms... But we have to take into account here some more specific properties : the statistic noise, the self attenuation of the radiation, the distance-dependant resolution. In this paper some correction process will be considered which can be more or less easily implemented depending of the algorithm used. Different compromises can be proposed : they depend strongly not only of the algorithm and the data-processing but also of the detector performances. In this field, this method will greatly take profit of the powerful calculators designed for the Radiographic tomodensitometry.

  10. Ergonomics Contribution in Maintainability

    Science.gov (United States)

    Teymourian, Kiumars; Seneviratne, Dammika; Galar, Diego

    2017-09-01

    The objective of this paper is to describe an ergonomics contribution in maintainability. The economical designs, inputs and training helps to increase the maintainability indicators for industrial devices. This analysis can be helpful, among other cases, to compare systems, to achieve a better design regarding maintainability requirements, to improve this maintainability under specific industrial environment and to foresee maintainability problems due to eventual changes in a device operation conditions. With this purpose, this work first introduces the notion of ergonomics and human factors, maintainability and the implementation of assessment of human postures, including some important postures to perform maintenance activities. A simulation approach is used to identify the critical posture of the maintenance personnel and implements the defined postures with minimal loads on the personnel who use the equipment in a practical scenario. The simulation inputs are given to the designers to improve the workplace/equipment in order to high level of maintainability. Finally, the work concludes summarizing the more significant aspects and suggesting future research.

  11. Application of the nuclear microprobe to the study of organic and inorganic composition of teeth irradiated by a laser beam

    International Nuclear Information System (INIS)

    Sommer, F.; Engelmann, Ch.; Couble, Ml.; Magloire, H.; Bonnin, P.

    1986-01-01

    The nuclear microprobe uses both direct observation of nuclear reactions induced by deuterons and X ray emission induced by protons or deuterons. Thanks to these techniques, concentration profiles of the main elements (C, N, P, Ca...) contained in different parts of healthy teeth (enamel, dentine and cementum) are drawn in control zones and laser irradiated zones. The results obtained show that important perturbations appear during the irradiation by the laser beam; we observe successively, depleted zones in carbon and nitrogen which contain calcium and phosphorus and hypomineralized zones which contain organic material. 10 refs [fr

  12. The role of a multiagent organization in the management of nuclear plants operational objectives

    Energy Technology Data Exchange (ETDEWEB)

    Papin, B.; Arnaud, G.; Fiche, Ch.; Dumas, M.

    1998-07-01

    The aim of the ESCRIME project, now reaching conclusions, was to optimize the collaboration between plant operators and computerized systems for the management of plant safety and availability. The requirement for putting such a collaboration into effective application was to clarify the operational strategies in order to enable a dialog between men and systems based on a ''shared representation'' of the plant operation. Thus a new vision of this operation, focusing on the completion of the plant fundamental objectives has been defined. This so-called means-ends strategy enables the simultaneous management of these objectives and provides explicit rules (priority...) to solve eventual conflicts (Physical interaction, sharing of resources...) apt to occur. The direct implementation of such strategies by the operators, using a dedicated man/machine interface, has made the object of the second phase of the ESCRIME project, already presented in LOEN in 1996. The third phase of the program, more prospective, aimed at finding an efficient way of sharing the management of plant objectives between the operator(s) and ''intelligent controllers'', preserving the role of the man in the decision loop and enabling him to maintain his awareness about the evolution of the plant. The multiagent organization has been identified as a promising way of sharing executive and decisive tasks between human and computerized agents. This organization, based on explicit ''social'' rules managing the negotiation between autonomous agents, appeared quite perfectly adapted to the management of conflicting objectives like in the means - ends strategy. The main problem to solve was, in fact, to check whether humans could be brought under this social organization in such a way as they could communicate and negotiate efficiently with the computerized agents. After a brief recall of the principles of the means - ends strategy for plant

  13. Unraveling the organization of the internal nuclear matrix: RNA-dependent anchoring of NuMA to a lamin scaffold.

    Science.gov (United States)

    Barboro, Paola; D'Arrigo, Cristina; Diaspro, Alberto; Mormino, Michele; Alberti, Ingles; Parodi, Silvio; Patrone, Eligio; Balbi, Cecilia

    2002-10-01

    Using quantitative immunoelectron microscopy we show here that when the nuclear matrix is isolated from rat hepatocytes in the presence of an inhibitor of RNase activity both lamins and the nuclear mitotic apparatus protein (NuMA) preferentially localize within the electron-dense domains of the internal nuclear matrix (INM). After RNA digestion NuMA undergoes a sharp depletion, while labeling by an antibody against lamins A and C within the electron-transparent regions increases, suggesting that a subset of lamin epitopes is masked by the interaction with RNA. We were able to explain this result by visualizing for the first time a thin web of lamin protofibrils which connects the electron-dense regions. Confirmation of these changes has been obtained by immunoblot analysis and confocal microscopy. As RNA digestion results both in the release of NuMA and in the collapse of the INM, we propose that a fraction of nuclear RNA brings about the association of NuMA islands with a lamin scaffold and that this interaction is required to maintain the latter in a state of high molecular dispersion.

  14. Environmental effectiveness of GAEC cross-compliance standard 2.2 "Maintaining the level of soil organic matter through crop rotation" and economic evaluation of the competitiveness gap for farmers

    Directory of Open Access Journals (Sweden)

    Lamberto Borrelli

    2015-11-01

    Full Text Available Within the Project MO.NA.CO was evaluated the Environmental effectiveness of GAEC cross-compliance standard 2.2 “Maintaining the level of soil organic matter through crop rotation” and economic evaluation of the competitiveness gap for farmers who support or not the cross-compliance regime. The monitoring was performed in nine experimental farms of the Council for Agricultural Research and Economics (CREA distributed throughout Italy and with different soil and climatic conditions. Were also evaluated the soil organic matter and some yield parameters, in a cereal monocropping (treatment counterfactual and a two-year rotation cereal-legume or forage (treatment factual. The two-years application of the standard “crop rotations” has produced contrasting results with regards to the storage of soil organic matter through crop rotation and these were not sufficient to demonstrate a statistically significant effect of treatment in any of the farms considered in monitoring, only in those farms subjected to more years of monitoring was recorded only a slight effect of the standard as a trend. The variations of organic matter in soils in response to changes in the culture technique or in the management of the soil may have long lag times and two years of time are not sufficient to demonstrate the dynamics of SOM associated with the treatment, also in consideration of the large inter annual variability recorded in different monitored sites.

  15. Nuclear medicine procedures for the evaluation of male sexual organs: a brief review

    Directory of Open Access Journals (Sweden)

    Mario Bernardo-Filho

    2008-12-01

    Full Text Available Sexuality consists of three aspects that are interrelated and inseparable, biological, physiological and social. The biological aspect considers the individual's capability to give and to receive pleasure. In consequence, it covers the functionality of the sexual organs and the physiology of human sexual response cycle. Diagnostic imaging modalities, such as single photon emission computed tomography (SPECT and positron emission tomography (PET have been used to evaluate clinical disorders of the male reproductive system. PET and SPECT procedures basically involve the administration of a radiopharmaceutical that has a higher uptake in a specific tumor or tissue. The aim of this brief review is to present some radiopharmaceuticals that have been used in the clinical evaluation of the male sexual organs (testes, prostate, seminal vesicles, penis related with male sexuality. This information could be useful in better understanding the male sexual response cycle, as well as the sexual disorders, when considering the male sexual organs and the pelvic floor. Moreover, the findings obtained with PET and SPECT imaging could help to evaluate the efficacy of clinical results of therapeutic procedures. In conclusion, the knowledge from these images could aid in better understanding the physiology of the different organs related with sexuality. Furthermore, they could be important tools to evaluate the physiological integrity of the involved organs, to improve clinical strategies and to accompany the patients under treatment.A sexualidade consiste de três aspectos que são inter-relacionados e inseparáveis: biólogico, fisiológico e social. O aspecto biológico considera a capacidade individual de dar e receber prazer. Em consequência, envolve a funcionalidade dos órgãos sexuais e a fisiologia do ciclo da resposta sexual humana. As imagens cintilográficas single photon emission computed tomography (SPECT e positron emission tomography (PET têm sido

  16. Nuclear security and radiological preparedness for the olympic games, athens 2004: lessons learned for organizing major public events.

    Science.gov (United States)

    Kamenopoulou, Vassiliki; Dimitriou, Panayiotis; Hourdakis, Constantine J; Maltezos, Antonios; Matikas, Theodore; Potiriadis, Constantinos; Camarinopoulos, Leonidas

    2006-10-01

    In light of the exceptional circumstances that arose from hosting the Olympic Games in Athens in 2004 and from recent terrorist events internationally, Greece attributes the highest priority to security issues. According to its statutory role, the Greek Atomic Energy Commission is responsible for emergency preparedness and response in case of nuclear and radiological events, and advises the Government on the measures and interventions necessary to protect the public. In this context, the Commission participated in the Nuclear, Radiological, Biological, and Chemical Threat National Emergency Plan, specially developed for the Olympic Games, and coordinated by the Olympic Games Security Division. The objective of this paper is to share the experience gained during the organization of the Olympic Games and to present the nuclear security program implemented prior to, during, and beyond the Games, in order to prevent, detect, assess, and respond to the threat of nuclear terrorism. This program adopted a multi-area coverage of nuclear security, including physical protection of nuclear and radiological facilities, prevention of smuggling of radioactive materials through borders, prevention of dispersion of these materials into the Olympic venues, enhancement of emergency preparedness and response to radiological events, upgrading of the technical infrastructure, establishment of new procedures for assessing the threat and responding to radiological incidents, and training personnel belonging to several organizations involved in the National Emergency Response Plan. Finally, the close cooperation of Greek Authorities with the International Atomic Energy Agency and the U.S. Department of Energy, under the coordination of the Greek Atomic Energy Commission, is also discussed.

  17. Cooperation of technical support organizations of state nuclear regulatory committee of Ukraine in sip safety regulation

    International Nuclear Information System (INIS)

    Bikov, V.O.; Kyilochits'ka, T.P.; Bogorins'kij, P.; Vasil'chenko, V.M.; Kondrat'jev, S.M.; Smishlyajeva, S.P.; Troter, D.

    2002-01-01

    The main task of the technical support in the Shelter Implementation Plan (SIP) licensing process consists in Technical Evaluation of SIP projects and documents submitted by the Licensee to State Nuclear Regulatory Committee to substantiate the safety of Shelter-related work. The goal of this task is to evaluate the submitted materials whether they meet the requirements of nuclear and radiation safety

  18. Assessing organizational culture in complex sociotechnical systems. Methodological evidence from studies in nuclear power plant maintenance organizations

    International Nuclear Information System (INIS)

    Reiman, T.

    2007-03-01

    Failures in industrial organizations dealing with hazardous technologies can have widespread consequences for the safety of the workers and the general population. Psychology can have a major role in contributing to the safe and reliable operation of these technologies. Most current models of safety management in complex sociotechnical systems such as nuclear power plant maintenance are either non-contextual or based on an overly-rational image of an organization. Thus, they fail to grasp either the actual requirements of the work or the socially-constructed nature of the work in question. The general aim of the present study is to develop and test a methodology for contextual assessment of organizational culture in complex sociotechnical systems. This is done by demonstrating the findings that the application of the emerging methodology produces in the domain of maintenance of a nuclear power plant (NPP). The concepts of organizational culture and organizational core task (OCT) are operationalized and tested in the case studies

  19. Oxidizing gel formulation for nuclear decontamination: rheological and acidic properties of the organic matrix and its ozonolysis

    International Nuclear Information System (INIS)

    Rouy, E.

    2003-10-01

    An acidic and oxidizing gel was formulated with a purely organic matrix, xanthan gum, at low concentrations (1 to 2 wt %). This polymer gel was investigated in various media (aqueous, acidic and ceric) by means of rheology: shear thinning behaviour, thixotropy, yield stress... Evidences of unexpected rheological properties in highly concentrated media show that xanthan is quite convenient for industrial projection of this type of gel on metallic walls in nuclear plants, notwithstanding its time-limited resistance to oxidation (about a few hours). Complexation mechanisms between ceric species and polar sites of the polymer led us to characterise acidic properties of our xanthan sample by potentiometric titration and 1 H NMR techniques. The matrix was finally treated by ozonolysis to suppress organic residues, as required to handle nuclear wastes. In acidic medium, ozonolysis of the gel was achieved successfully while in acidic and ceric medium this process showed limited efficiency, needing further investigation to be clarified. (author)

  20. Extremely fast increase in the organic loading rate during the co-digestion of rapeseed oil and sewage sludge in a CSTR--characterization of granules formed due to CaO addition to maintain process stability.

    Science.gov (United States)

    Kasina, M; Kleyböcker, A; Michalik, M; Würdemann, H

    2015-01-01

    In a co-digestion system running with rapeseed oil and sewage sludge, an extremely fast increase in the organic loading rate was studied to develop a procedure to allow for flexible and demand-driven energy production. The over-acidification of the digestate was successfully prevented by calcium oxide dosage, which resulted in granule formation. Mineralogical analyses revealed that the granules were composed of insoluble salts of long chain fatty acids and calcium and had a porous structure. Long chain fatty acids and calcium formed the outer cover of granules and offered interfaces on the inside thereby enhancing the growth of biofilms. With granule size and age, the pore size increased and indicated degradation of granular interfaces. A stable biogas production up to the organic loading rate of 10.4 kg volatile solids m(-3) d(-1) was achieved although the hydrogen concentration was not favorable for propionic acid degradation. However, at higher organic loading rates, unbalanced granule formation and degradation were observed. Obviously, the adaption time for biofilm growth was too short to maintain the balance, thereby resulting in a low methane yield.

  1. Application of nuclear technique to assess the optimization and benefits from bio and organic fertilization of some vegetables

    International Nuclear Information System (INIS)

    EL Sayed, A.F.A.A.

    2012-01-01

    Two field experiments were, conducted in the Plant Nutrition and Fertilization Unit, Soils and Water Department Nuclear Research Center, Atomic Energy Authority, Inshas, Egypt, assessing application of N in totally organic or totally mineral or different mixtures with the rat of N (being fixed) with or without bio fertilizers carried out following design factorial complete block design with three replicates .In the first one, pea was planted and in the second cucumber was planted in the same plots. This study was planned to Determine the contribution of mineral, organic and bio fertilizers in supplying plant with nitrogen using nuclear technology 15 N and assess the optimization and benefits from bio and organic fertilization of some vegetables .Fertilization treatments indicated that the combination of 50% mineral fertilizer + 50% organic compost was superior over all other treatments. It means that half of the recommended dose of mineral fertilizer is enough to meet the requirement of pea and cucumber crops when supplemented with organic compost. This combination may have an environmental impact since it would reduce the risks of chemical fertilizers.

  2. Visitor centres at nuclear facility sites how are they organized: what information do they provide

    International Nuclear Information System (INIS)

    Sorin, F.

    1993-01-01

    A large proportion of visitors consists in school children. The centre receives an average of 12 000 visitors a year. It regularly advertises its services through information campaigns and sometimes pays for advertising. Not a target for anti-nuclear demonstrations, it may receive some support from local authorities. Designed for the lay public, the Centre gives out concise and condensed information relating in equal measure to the nuclear power plant to which it is attached and nuclear energy in general (mentioning other applications of nuclear power and other energy sources). The information given is a neutral account of the facts rather than arguments justifying and promoting the use of nuclear energy. These Visitor Centres can be considered as an essential element in educating public opinion about nuclear energy. Furthermore, beyond the nuclear debate properly so-called, these Visitor Centres, together with science and technology museums, constitute one of the first vehicles in the world for disseminating scientific and technical knowledge to the general public

  3. Neptuno-nuclear European platform of training and university organizations project

    International Nuclear Information System (INIS)

    Comsa, Olivia; Meglea, Claudia; Banutoiu, Marina; Paraschiva, M. V.; Meglea, S.

    2003-01-01

    The project focuses on a harmonised approach to education and training in nuclear engineering in Europe and its implementation, including better integration of national resources and capabilities. The expected result is an operational network for training and life-long learning schemes as well as for academic education at the master, doctoral and post doctoral degree, underpinning: - sustainability of European's excellence in nuclear technology; - harmonised approaches to safety and best practices, both operational and regulatory at European level in Member States and Accession Countries; - preservation of competence and expertise for the continued safe use of nuclear energy and other uses of irradiations in industry and medicine; - harmonised approach for training and education in nuclear engineering. In the network: - we implement the roadmap for nuclear education in Europe as developed and demonstrated in the ongoing Euratom FP5 project ENEM; - we warrant the end-user relevance of the education at all levels by recruiting (part-time) professors out of industry and by providing (re-)training of nuclear industry personnel; - we teach advanced courses preferably at selected centres of excellence; - bridging leading edge research and new knowledge generation with teaching and education; -creating nuclei of excellence for doctoral schools in nuclear engineering and sciences; - we facilitate transnational access to research infrastructure. The final aim of the NEPTUNO initiative is to guarantee sufficient people, means and knowledge (resources) to make possible the safe and efficient applications of the nuclear technology to the civil and industry in the medium and long term. This will be accomplished by the design, development and testing of a system able to achieve the sustainable integration of education and training in nuclear engineering and safety in Europe. Thus, by responding to the EC objective for call for proposals, a joint approach to be widely applied in

  4. Diversity & Community: Maintaining Allegiances.

    Science.gov (United States)

    Pena, Devon G.

    1990-01-01

    The quest for diversity must overcome the resistance of traditional White, male faculty to redefining the mission and curriculum of the liberal arts college. Change will be difficult, but it must occur if liberal arts colleges are to survive and maintain a central and relevant place in multicultural America. (MSE)

  5. Maintaining an Environmental Balance

    Science.gov (United States)

    Environmental Science and Technology, 1976

    1976-01-01

    A recent conference of the National Environmental Development Association focused on the concepts of environment, energy and economy and underscored the necessity for balancing the critical needs embodied in these issues. Topics discussed included: nuclear energy and wastes, water pollution control, federal regulations, environmental technology…

  6. Exposing Exposure: Enhancing Patient Safety through Automated Data Mining of Nuclear Medicine Reports for Quality Assurance and Organ Dose Monitoring

    Science.gov (United States)

    Ikuta, Ichiro; Wasser, Elliot J.; Warden, Graham I.; Gerbaudo, Victor H.; Khorasani, Ramin

    2012-01-01

    Purpose: To develop and validate an open-source informatics toolkit capable of creating a radiation exposure data repository from existing nuclear medicine report archives and to demonstrate potential applications of such data for quality assurance and longitudinal patient-specific radiation dose monitoring. Materials and Methods: This study was institutional review board approved and HIPAA compliant. Informed consent was waived. An open-source toolkit designed to automate the extraction of data on radiopharmaceuticals and administered activities from nuclear medicine reports was developed. After iterative code training, manual validation was performed on 2359 nuclear medicine reports randomly selected from September 17, 1985, to February 28, 2011. Recall (sensitivity) and precision (positive predictive value) were calculated with 95% binomial confidence intervals. From the resultant institutional data repository, examples of usage in quality assurance efforts and patient-specific longitudinal radiation dose monitoring obtained by calculating organ doses from the administered activity and radiopharmaceutical of each examination were provided. Results: Validation statistics yielded a combined recall of 97.6% ± 0.7 (95% confidence interval) and precision of 98.7% ± 0.5. Histograms of administered activity for fluorine 18 fluorodeoxyglucose and iodine 131 sodium iodide were generated. An organ dose heatmap which displays a sample patient’s dose accumulation from multiple nuclear medicine examinations was created. Conclusion: Large-scale repositories of radiation exposure data can be extracted from institutional nuclear medicine report archives with high recall and precision. Such repositories enable new approaches in radiation exposure patient safety initiatives and patient-specific radiation dose monitoring. © RSNA, 2012 PMID:22627599

  7. The economics of nuclear power: four essays on the role of innovation and industrial organization

    International Nuclear Information System (INIS)

    Berthelemy, Michel

    2013-01-01

    This thesis studies the role of innovation and industrial structures in the nuclear power sector. The analysis of innovation is based on the use of patent data as a measure of innovation effort. On the one hand, we study the determinants of innovation and, on the other hand, its impact on operating and safety performance of existing nuclear reactors and on construction costs. We show that nuclear safety regulation can induce innovation and improve safety performance, but at the same time contributes to increases in construction costs. The analysis of the role of industrial structures allows us to study the impact of learning by doing opportunities both for construction and operation of reactors, as well as the effect of electricity market liberalization on operating performance. In particular, we show that the divestiture of electricity production and distribution activities induces a substantial improvement in the availability of nuclear reactors. (author)

  8. Nuclear Knowledge Management: the IAEA Approach

    International Nuclear Information System (INIS)

    Sbaffoni, M.; De Grosbois, J.

    2015-01-01

    Knowledge in an organization is residing in people, processes and technology. Adequate awareness of their knowledge assets and of the risk of losing them is vital for safe and secure operations of nuclear installations. Senior managers understand this important linkage, and in the last years there is an increasing tendency in nuclear organizations to implement knowledge management strategies to ensure that the adequate and necessary knowledge is available at the right time, in the right place. Specific and advanced levels of knowledge are clearly required to achieve and maintain technical expertise, and experience must be developed and be available throughout the nuclear technology lifecycle. If a nuclear organization does not possess or have access to the required technical knowledge, a full understanding of the potential consequences of decisions and actions may not be possible, and safety, security and safeguards might be compromised. Effective decision making during design, licencing, procurement, construction, commissioning, operation, maintenance, refurbishment, and decommissioning of nuclear facilities needs to be risk-informed and knowledge-driven. Nuclear technology is complex and brings with it inherent and unique risks that must be managed to acceptably low levels. Nuclear managers have a responsibility not only to establish adequate technical knowledge and experience in their nuclear organizations but also to maintain it. The consequences of failing to manage the organizations key knowledge assets can result in serious degradations or accidents. The IAEA Nuclear Knowledge Management (NKM) sub-programme was established more than 10 years ago to support Nuclear Organizations, at Member States request, in the implementation and dissemination of the NKM methodology, through the development of guidance and tools, and by providing knowledge management services and assistance. The paper will briefly present IAEA understanding of and approach to knowledge

  9. Maintaining dignity in vulnerability

    DEFF Research Database (Denmark)

    Høy, Bente

    2016-01-01

    Background. Older people, living in nursing homes, are exposed to diverse situations, which may be associated with loss of dignity. To help them maintain their dignity, it is important to explore, how dignity is preserved in such context. Views of dignity and factors influencing dignity have been...... studied from both the residents´ and the care pro-viders´ perspective. However, most of these studies pertain to experiences in the dying or the illness context. Knowledge is scarce about how older people experience their dig-nity within their everyday lives in nursing homes. Aim To illuminate the meaning...... of maintaining dignity from the perspective of older people living in nursing homes Method. This qualitative study is based on individual interviews. Twenty-eight nursing home residents were included from six nursing homes in Scandinavia. A phenomenolog-ical-hermeneutic approach, inspired by Ricoeur was used...

  10. Modeling the Emission Spectra of Organic Molecules: A Competition between Franck-Condon and Nuclear Ensemble Methods.

    Science.gov (United States)

    de Sousa, Leonardo Evaristo; Ribeiro, Luiz Antonio; Fonseca, Antonio Luciano de Almeida; da Silva Filho, Demétrio Antonio

    2016-07-14

    The emission spectra of flexible and rigid organic molecules are theoretically investigated in the framework of the Franck-Condon (FC) and nuclear ensemble (NE) approaches, both of which rely on results from density functional theory but differ in the way vibrational contributions are taken into account. Our findings show that the emission spectra obtained using the NE approach are in better agreement with experiment than the ones produced by FC calculations considering both rigid and flexible molecules. Surprisingly, the description of a suitable balance between the vibronic progression and the emission spectra envelope shows dependency on the initial sampling for the NE calculations which must be judiciously selected. Our results intend to provide guidance for a better theoretical description of light emission properties of organic molecules with applications in organic electronic devices.

  11. Characterization of clay minerals and organic matter in shales: Application to high-level nuclear waste isolation

    International Nuclear Information System (INIS)

    Gueven, N.; Landis, C.R.; Jacobs, G.K.

    1988-10-01

    The objective of the Sedimentary Rock Program at the Oak Ridge National Laboratory is to conduct investigations to assess the potential for shale to serve as a host medium for the isolation of high-level nuclear wastes. The emphasis on shale is a result of screening major sedimentary rock types (shale, sandstone, carbonate , anhydrite, and chalk) for a variety of attributes that affect the performance of repositories. The retardation of radionuclides was recognized as one of the potentially favorable features of shale. Because shale contains both clay minerals and organic matter, phases that may provide significant sorption of radioelement, the characterization of these phases is essential. In addition, the organic matter in shale has been identified as a critical area for study because of its potential to play either a favorable (reductant) or deleterious (organic ligands) role in the performance of a repository sited in shale. 36 refs., 36 figs., 10 tabs

  12. Microorganisms maintain crowding homeostasis

    NARCIS (Netherlands)

    van den Berg, Jonas; Boersma, Arnold J; Poolman, Bert

    2017-01-01

    Macromolecular crowding affects the mobility of biomolecules, protein folding and stability, and the association of macromolecules with each other. Local differences in crowding that arise as a result of subcellular components and supramolecular assemblies contribute to the structural organization

  13. Nuclear non proliferation strategy and interstate organizations: the IAEA powerlessness in the Iranian example?

    International Nuclear Information System (INIS)

    Cuignet, J.F.

    2008-01-01

    In this study, the author questions the efficiency of the IAEA in its mission of control, prevention and mediation, and wanders whether it will succeed in preventing Iran to acquire nuclear technology. He gives a brief description of the demographic and economic situation of Iran, of its security issues. After a comparison of Iraq and Iran, he describes means and tools which are available to the IAEA, mainly the NPT (sanctions, operation, limitations and opportunities), and outlines the fact that acquiring the nuclear weapon is nowhere forbidden and that the USA are not a good example as far as nuclear weapons are concerned. Then, he tries to show the way to a pacific solution: even if multipolarity is more difficult to manage than a hyper-power status for the United States, they would be unable to sustain a new conflict; the IAEA is more prudent after the Iraqi failure and did not receive its mandate from the USA

  14. Forest type effects on the retention of radiocesium in organic layers of forest ecosystems affected by the Fukushima nuclear accident

    Science.gov (United States)

    Koarashi, Jun; Atarashi-Andoh, Mariko; Matsunaga, Takeshi; Sanada, Yukihisa

    2016-01-01

    The Fukushima Daiichi nuclear power plant disaster caused serious radiocesium (137Cs) contamination of forest ecosystems over a wide area. Forest-floor organic layers play a key role in controlling the overall bioavailability of 137Cs in forest ecosystems; however, there is still an insufficient understanding of how forest types influence the retention capability of 137Cs in organic layers in Japanese forest ecosystems. Here we conducted plot-scale investigations on the retention of 137Cs in organic layers at two contrasting forest sites in Fukushima. In a deciduous broad-leaved forest, approximately 80% of the deposited 137Cs migrated to mineral soil located below the organic layers within two years after the accident, with an ecological half-life of approximately one year. Conversely, in an evergreen coniferous forest, more than half of the deposited 137Cs remained in the organic layers, with an ecological half-life of 2.1 years. The observed retention behavior can be well explained by the tree phenology and accumulation of 137Cs associated with litter materials with different degrees of degradation in the organic layers. Spatial and temporal patterns of gamma-ray dose rates depended on the retention capability. Our results demonstrate that enhanced radiation risks last longer in evergreen coniferous forests than in deciduous broad-leaved forests. PMID:27974832

  15. Analysis of the organization implemented by a nuclear operator for ensuring the safety of his facilities: contribution of case studies

    International Nuclear Information System (INIS)

    Jeffroy, F.; Conte, D.

    2006-01-01

    This article is the chapter 6 of this book. It deals with the organization implemented by a nuclear operator and its suitability in warranting the safety of his facilities. An analysis approach has been defined which takes into consideration the formal aspect of the rules, structures and resources implemented by the organization, and which considers also the operational aspect through the collective activity of actors. The operation dynamics of the organisation has been approached through retrospective case studies aiming at understanding, from actors' contributions to the processing of events, how the characteristics of the organization were representing resources or constraints for the actors. This approach of organization through case studies must be put forward in the present day debate about cognitive ergonomics in sociology of organizations and in management. Several works try to put in relation the activity of 'front line' actors with the decisions and orientations taken at the strategic level. This supposes that one can combine an analysis of actors' activity integrating their point of view and and analysis of the structures and resources that are supplied to them by the organization. (J.S.)

  16. Forest type effects on the retention of radiocesium in organic layers of forest ecosystems affected by the Fukushima nuclear accident

    Science.gov (United States)

    Koarashi, Jun; Atarashi-Andoh, Mariko; Matsunaga, Takeshi; Sanada, Yukihisa

    2016-12-01

    The Fukushima Daiichi nuclear power plant disaster caused serious radiocesium (137Cs) contamination of forest ecosystems over a wide area. Forest-floor organic layers play a key role in controlling the overall bioavailability of 137Cs in forest ecosystems; however, there is still an insufficient understanding of how forest types influence the retention capability of 137Cs in organic layers in Japanese forest ecosystems. Here we conducted plot-scale investigations on the retention of 137Cs in organic layers at two contrasting forest sites in Fukushima. In a deciduous broad-leaved forest, approximately 80% of the deposited 137Cs migrated to mineral soil located below the organic layers within two years after the accident, with an ecological half-life of approximately one year. Conversely, in an evergreen coniferous forest, more than half of the deposited 137Cs remained in the organic layers, with an ecological half-life of 2.1 years. The observed retention behavior can be well explained by the tree phenology and accumulation of 137Cs associated with litter materials with different degrees of degradation in the organic layers. Spatial and temporal patterns of gamma-ray dose rates depended on the retention capability. Our results demonstrate that enhanced radiation risks last longer in evergreen coniferous forests than in deciduous broad-leaved forests.

  17. Regulatory challenges for independent organization and licensing procedures for Egypt first nuclear power program

    International Nuclear Information System (INIS)

    Elsheikh, B.M.

    2012-01-01

    In March 2010 the Government of Egypt issued an Ordinance creating an independent regulatory body the Egypt Nuclear and Radiological Regulatory Authority (NRRA) reporting directly to the Prime Minister and responsible for matters dealing with protection of the radiation worker, public and environment from the harmful effects of ionizing radiation. A little more than 2 years have elapsed since this date. Some of the challenges faced by NRRA to its regulatory independence are given below. This paper will discuss the major challenges relating to Egyptian nuclear power program and specially the regulatory effectiveness and licensing procedures compared to international comparison.

  18. Organization and practices on regulatory review in the licensing process of nuclear power plants in Spain

    International Nuclear Information System (INIS)

    Trueba, P.

    1979-01-01

    The actual organisation, practices and experience of the JEN Nuclear Safety Department on the regulatory review in the licensing process of nuclear power plants in Spain, are presented. Topics to be covered are: The structure, organisation, staff and principal functional areas of the NSD, the academic qualifications and work experience of the NSD personnel, recruiting and training, the conduct of the regulatory review during the licensing process and working procedures, the manpower and coverage of the different technical areas, the principal problems and conclusions. (author)

  19. NRC - regulator of nuclear safety

    International Nuclear Information System (INIS)

    1997-01-01

    The U.S. Nuclear Regulatory Commission (NRC) was formed in 1975 to regulate the various commercial and institutional uses of nuclear energy, including nuclear power plants. The agency succeeded the Atomic Energy Commission, which previously had responsibility for both developing and regulating nuclear activities. Federal research and development work for all energy sources, as well as nuclear weapons production, is now conducted by the U.S. Department of Energy. Under its responsibility to protect public health and safety, the NRC has three principal regulatory functions: (1) establish standards and regulations, (2) issue licenses for nuclear facilities and users of nuclear materials, and (3) inspect facilities and users of nuclear materials to ensure compliance with the requirements. These regulatory functions relate to both nuclear power plants and to other uses of nuclear materials - like nuclear medicine programs at hospitals, academic activities at educational institutions, research work, and such industrial applications as gauges and testing equipment. The NRC places a high priority on keeping the public informed of its work. The agency recognizes the interest of citizens in what it does through such activities as maintaining public document rooms across the country and holding public hearings, public meetings in local areas, and discussions with individuals and organizations

  20. Alkylation and pre-organization of diglycolamide ligands on flexible platforms for nuclear waste treatment

    NARCIS (Netherlands)

    Leoncini, Andrea

    2017-01-01

    The research topic of this thesis concerns the synthesis and evaluation of new diglycolamide (DGA) ligands for the extraction and (potential) separation of actinide and lanthanide ions from bulk spent nuclear fuel. This work was aimed at the development of new pre-organised ligands with improved

  1. Disruption of Nuclear Organization during the Initial Phase of African Swine Fever Virus Infection ▿

    Science.gov (United States)

    Ballester, Maria; Rodríguez-Cariño, Carolina; Pérez, Mónica; Gallardo, Carmina; Rodríguez, Javier M.; Salas, María L.; Rodriguez, Fernando

    2011-01-01

    African swine fever virus (ASFV), the causative agent of one of the most devastating swine diseases, has been considered exclusively cytoplasmic, even though some authors have shown evidence of an early stage of nuclear replication. In the present study, an increment of lamin A/C phosphorylation was observed in ASFV-infected cells as early as 4 h postinfection, followed by the disassembling of the lamina network close to the sites where the viral genome starts its replication. At later time points, this and other nuclear envelope markers were found in the cytoplasm of the infected cells. The effect of the infection on the cell nucleus was much more severe than previously expected, since a redistribution of other nuclear proteins, such as RNA polymerase II, the splicing speckle SC-35 marker, and the B-23 nucleolar marker, was observed from 4 h postinfection. All this evidence, together with the redistribution, dephosphorylation, and subsequent degradation of RNA polymerase II after ASFV infection, suggests the existence of sophisticated mechanisms to regulate the nuclear machinery during viral infection. PMID:21680527

  2. Identification and characterization of proteins involved in nuclear organization using Drosophila GFP protein trap lines.

    Directory of Open Access Journals (Sweden)

    Margaret Rohrbaugh

    Full Text Available Strains from a collection of Drosophila GFP protein trap lines express GFP in the normal tissues where the endogenous protein is present. This collection can be used to screen for proteins distributed in the nucleus in a non-uniform pattern.We analyzed four lines that show peripheral or punctate nuclear staining. One of these lines affects an uncharacterized gene named CG11138. The CG11138 protein shows a punctate distribution in the nuclear periphery similar to that of Drosophila insulator proteins but does not co-localize with known insulators. Interestingly, mutations in Lamin proteins result in alterations in CG11138 localization, suggesting that this protein may be a novel component of the nuclear lamina. A second line affects the Decondensation factor 31 (Df31 gene, which encodes a protein with a unique nuclear distribution that appears to segment the nucleus into four different compartments. The X-chromosome of males is confined to one of these compartments. We also find that Drosophila Nucleoplasmin (dNlp is present in regions of active transcription. Heat shock leads to loss of dNlp from previously transcribed regions of polytene chromosome without redistribution to the heat shock genes. Analysis of Stonewall (Stwl, a protein previously found to be necessary for the maintenance of germline stem cells, shows that Stwl is present in a punctate pattern in the nucleus that partially overlaps with that of known insulator proteins. Finally we show that Stwl, dNlp, and Df31 form part of a highly interactive network. The properties of other components of this network may help understand the role of these proteins in nuclear biology.These results establish screening of GFP protein trap alleles as a strategy to identify factors with novel cellular functions. Information gained from the analysis of CG11138 Stwl, dNlp, and Df31 sets the stage for future studies of these proteins.

  3. Recent improvement in organization and in tutorial practices in the National Institute of Nuclear Sciences and Techniques

    International Nuclear Information System (INIS)

    Maziere, D.

    2002-01-01

    The National Institute of Nuclear Sciences and Techniques has recently improved its organization and its tutorial practices to increase efficiency of training. It obtained in 2001 an ISO 9001 certification aiming at a better satisfaction of customers. Moreover, external contributors and INSTN people in charge of pedagogy are strongly encouraged to vary tutorial methods and are proposed to be trained for these new teaching techniques. For next years, trends are not missing to increase efficiency: a better listening to the customers, block-release training, e-learning, increasing European commitments. Nevertheless relevant evaluation of efficiency remains the unresolved issue and this could never be done by the training institution alone. (author)

  4. FLUIDIZED BED STEAM REFORMING MINERALIZATION FOR HIGH ORGANIC AND NITRATE WASTE STREAMS FOR THE GLOBAL NUCLEAR ENERGY PARTNERSHIP

    Energy Technology Data Exchange (ETDEWEB)

    Jantzen, C; Michael Williams, M

    2008-01-11

    Waste streams that may be generated by the Global Nuclear Energy Partnership (GNEP) Advanced Energy Initiative may contain significant quantities of organics (0-53 wt%) and/or nitrates (0-56 wt%). Decomposition of high nitrate streams requires reducing conditions, e.g. organic additives such as sugar or coal, to reduce the NO{sub x} in the off-gas to N{sub 2} to meet the Clean Air Act (CAA) standards during processing. Thus, organics will be present during waste form stabilization regardless of which GNEP processes are chosen, e.g. organics in the feed or organics for nitrate destruction. High organic containing wastes cannot be stabilized with the existing HLW Best Developed Available Technology (BDAT) which is HLW vitrification (HLVIT) unless the organics are removed by preprocessing. Alternative waste stabilization processes such as Fluidized Bed Steam Reforming (FBSR) operate at moderate temperatures (650-750 C) compared to vitrification (1150-1300 C). FBSR converts organics to CAA compliant gases, creates no secondary liquid waste streams, and creates a stable mineral waste form that is as durable as glass. For application to the high Cs-137 and Sr-90 containing GNEP waste streams a single phase mineralized Cs-mica phase was made by co-reacting illite clay and GNEP simulated waste. The Cs-mica accommodates up to 30% wt% Cs{sub 2}O and all the GNEP waste species, Ba, Sr, Rb including the Cs-137 transmutation to Ba-137. For reference, the cesium mineral pollucite (CsAlSi{sub 2}O{sub 6}), currently being studied for GNEP applications, can only be fabricated at {ge} 1000 C. Pollucite mineralization creates secondary aqueous waste streams and NO{sub x}. Pollucite is not tolerant of high concentrations of Ba, Sr or Rb and forces the divalent species into different mineral host phases. The pollucite can accommodate up to 33% wt% Cs{sub 2}O.

  5. Jerome Lewis Duggan: A Nuclear Physicist and a Well-Known, Six-Decade Accelerator Application Conference (CAARI) Organizer

    Science.gov (United States)

    Del McDaniel, Floyd; Doyle, Barney L.

    Jerry Duggan was an experimental MeV-accelerator-based nuclear and atomic physicist who, over the past few decades, played a key role in the important transition of this field from basic to applied physics. His fascination for and application of particle accelerators spanned almost 60 years, and led to important discoveries in the following fields: accelerator-based analysis (accelerator mass spectrometry, ion beam techniques, nuclear-based analysis, nuclear microprobes, neutron techniques); accelerator facilities, stewardship, and technology development; accelerator applications (industrial, medical, security and defense, and teaching with accelerators); applied research with accelerators (advanced synthesis and modification, radiation effects, nanosciences and technology); physics research (atomic and molecular physics, and nuclear physics); and many other areas and applications. Here we describe Jerry’s physics education at the University of North Texas (B. S. and M. S.) and Louisiana State University (Ph.D.). We also discuss his research at UNT, LSU, and Oak Ridge National Laboratory, his involvement with the industrial aspects of accelerators, and his impact on many graduate students, colleagues at UNT and other universities, national laboratories, and industry and acquaintances around the world. Along the way, we found it hard not to also talk about his love of family, sports, fishing, and other recreational activities. While these were significant accomplishments in his life, Jerry will be most remembered for his insight in starting and his industry in maintaining and growing what became one of the most diverse accelerator conferences in the world — the International Conference on the Application of Accelerators in Research and Industry, or what we all know as CAARI. Through this conference, which he ran almost single-handed for decades, Jerry came to know, and became well known by, literally thousands of atomic and nuclear physicists, accelerator

  6. Maintaining the Harmonious Family

    DEFF Research Database (Denmark)

    Jonasson, Charlotte; Lauring, Jakob

    2006-01-01

    Harmony and social sustainability has been described as almost inborn aspects of Korean corporations dating far back in history. After the East Asian economic crisis in 1997, however, most Korean organizations faced new demands for productivity and competitiveness. Sustaining the fragile balance ...

  7. Maintaining Relationship Based Procurement

    Directory of Open Access Journals (Sweden)

    Peter Davis

    2012-11-01

    Full Text Available Alliance and relationship projects are increasingin number and represent a large pool of work. Tobe successful relationship style contracts dependon soft-dollar factors, particularly the participants'ability to work together within an agreedframework, generally they are not based on lowbid tendering. Participants should be prepared todo business in an open environment based ontrust and mutually agreed governance. Theresearch evaluates relationship maintenance inthe implementation phase of constructionalliances - a particular derivative of relationshipstyle contracts. To determine the factors thatcontribute to relationship maintenance forty-nineexperienced Australian alliance projectmanagers were interviewed. The main findingswere; the development of relationships early inthe project form building blocks of success fromwhich relationships are maintained and projectvalue added; quality facilitation plays animportant part in relationship maintenance and ahybrid organisation created as a result of alliancedevelopment overcomes destructiveorganisational boundaries. Relationshipmaintenance is integral to alliance project controland failure to formalise it and pay attention toprocess and past outcomes will undermine analliance project's potential for success.

  8. Nuclear Safety Review for 2014

    International Nuclear Information System (INIS)

    2014-07-01

    The Nuclear Safety Review 2014 focuses on the dominant nuclear safety trends, issues and challenges in 2013. The Executive Overview provides general nuclear safety information along with a summary of the major issues covered in this report: strengthening safety in nuclear installations; improving radiation, transport and waste safety; enhancing emergency preparedness and response (EPR); improving regulatory infrastructure and effectiveness; and strengthening civil liability for nuclear damage. The Appendix provides details on the activities of the Commission on Safety Standards, and activities relevant to the Agency’s safety standards. The global nuclear community has made steady and continuous progress in strengthening nuclear safety in 2013, as promoted by the IAEA Action Plan on Nuclear Safety (hereinafter referred to as “the Action Plan”) and reported in Progress in the Implementation of the IAEA Action Plan on Nuclear Safety (document GOV/INF/2013/8-GC(57)/INF/5), and the Supplementary Information to that report and Progress in the Implementation of the IAEA Action Plan on Nuclear Safety (document GOV/INF/2014/2). • Significant progress continues to be made in several key areas, such as assessments of safety vulnerabilities of nuclear power plants (NPPs), strengthening of the Agency’s peer review services, improvements in EPR capabilities, strengthening and maintaining capacity building, and protecting people and the environment from ionizing radiation. The progress that has been made in these and other areas has contributed to the enhancement of the global nuclear safety framework. • Significant progress has also been made in reviewing the Agency’s safety standards, which continue to be widely applied by regulators, operators and the nuclear industry in general, with increased attention and focus on vitally important areas such as design and operation of NPPs, protection of NPPs against severe accidents, and EPR. • The Agency continued to

  9. Improving the Indico Framework at the European Organization for Nuclear Research - Internship Report - LEIC 2006/2007 (FEUP)

    CERN Document Server

    Ferreira, Jose Pedro

    2007-01-01

    This document describes the work developed by José Pedro Macedo Alves Ferreira, Informatics Engineering and Computing (LEIC) undergraduate student at the Engineering Faculty of the University of Porto (FEUP), in the context of the project "Improving the Indico Framework". The project took place at the European Organization for Nuclear Research (CERN), in the framework of both the Technical Student Program of this organization, and the curricular internship of the aforementioned degree. The contents of this report refer to the internship period, the first half of the one-year Technical Student program. The project aimed to introduce usability improvements into an already existing web application, the Indico platform, a integrated system for event scheduling and management, which was initially developed as a European project and continued by CERN, being currently used by several institutions worldwide. Indico presented some usability issues that for long had been noticed by the users and required correction, m...

  10. Cementation of secondary wastes generated from carbonisation of spent organic ion exchange resins from nuclear power plants

    International Nuclear Information System (INIS)

    Sathi Sasidharan, N.; Deshingkar, D.S.; Wattal, P.K.

    2004-07-01

    The spent IX resins containing radioactive fission and activation products from power reactors are highly active solid wastes generated during operations of nuclear reactors. Process for carbonization of IX resins to achieve weight and volume reduction has been optimized on 50 dm 3 /batch pilot test rig. The process generates carbonaceous residue, organic liquid condensates (predominantly styrene) and aqueous alkaline scrubber solutions as secondary wastes. The report discusses laboratory tests on leaching of 137 Cs from cement matrix incorporating carbonaceous residues and extrapolation of results to 200 liter matrix block. The cumulative fraction of 137 Cs leached from 200 liter cement matrix was estimated to be 0.0021 in 200 days and 0.0418 over a period of 30 years. Incorporation of organic liquid condensates into cement matrix has been tried out successfully. Thus two types of secondary wastes generated during carbonization of spent IX resins can be immobilized in cement matrix. (author)

  11. INTEGRAL BENCHMARK DATA FOR NUCLEAR DATA TESTING THROUGH THE ICSBEP AND THE NEWLY ORGANIZED IRPHEP

    Energy Technology Data Exchange (ETDEWEB)

    J. Blair Briggs; Lori Scott; Yolanda Rugama; Enrico Satori

    2007-04-01

    The status of the International Criticality Safety Benchmark Evaluation Project (ICSBEP) was last reported in a nuclear data conference at the International Conference on Nuclear Data for Science and Technology, ND-2004, in Santa Fe, New Mexico. Since that time the number and type of integral benchmarks have increased significantly. Included in the ICSBEP Handbook are criticality-alarm / shielding and fundamental physic benchmarks in addition to the traditional critical / subcritical benchmark data. Since ND 2004, a reactor physics counterpart to the ICSBEP, the International Reactor Physics Experiment Evaluation Project (IRPhEP) was initiated. The IRPhEP is patterned after the ICSBEP, but focuses on other integral measurements, such as buckling, spectral characteristics, reactivity effects, reactivity coefficients, kinetics measurements, reaction-rate and power distributions, nuclide compositions, and other miscellaneous-type measurements in addition to the critical configuration. The status of these two projects is discussed and selected benchmarks highlighted in this paper.

  12. Australian Nuclear Science and Technology Organization. Annual Report 1995-1996

    International Nuclear Information System (INIS)

    1996-09-01

    The report provides an overview of the outcomes achieved and the current activities of ANSTO related to its core business activities. The core business of ANSTO were identified as follows: international strategic relevance of nuclear science; core facilities operation and development; applications of nuclear science and technology to the understanding of natural processes; treatment and management of man-made and naturally occurring radioactive substances; competitiveness and ecological sustainability of industry and organizational development and support. The report also include specific reporting against those performance indicators that were negotiated with the Government as part of the Triennium Funding Agreement and are regarded as appropriate for science agencies or for ANSTO specifically. Contains a glossary and an detailed index. tables., figures

  13. Australian Nuclear Science and Technology Organization. Annual Report 1995-1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-09-01

    The report provides an overview of the outcomes achieved and the current activities of ANSTO related to its core business activities. The core business of ANSTO were identified as follows: international strategic relevance of nuclear science; core facilities operation and development; applications of nuclear science and technology to the understanding of natural processes; treatment and management of man-made and naturally occurring radioactive substances; competitiveness and ecological sustainability of industry and organizational development and support. The report also include specific reporting against those performance indicators that were negotiated with the Government as part of the Triennium Funding Agreement and are regarded as appropriate for science agencies or for ANSTO specifically. Contains a glossary and an detailed index. tables., figures.

  14. Nuclear organization of PML bodies in leukaemic and multiple myeloma cells

    Czech Academy of Sciences Publication Activity Database

    Kroupová, Jana; Harničarová, Andrea; Kůrová, Jana; Uhlířová, Radka; Kozubek, Stanislav; Legartová, Soňa; Hájek, R.; Bártová, Eva

    2008-01-01

    Roč. 32, č. 12 (2008), s. 1866-1877 ISSN 0145-2126 R&D Projects: GA ČR(CZ) GA204/06/0978; GA MŠk(CZ) LC06027 Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702 Keywords : PML bodies * nuclear arrangement * leukaemic cells Subject RIV: BO - Biophysics Impact factor: 2.390, year: 2008

  15. Chromatin organization at the nuclear periphery as revealed by image analysis of structured illumination microscopy data

    Czech Academy of Sciences Publication Activity Database

    Fišerová, Jindřiška; Efenberková, Michaela; Sieger, T.; Maninová, Miloslava; Uhlířová, Jana; Hozák, Pavel

    2017-01-01

    Roč. 130, č. 12 (2017), s. 2066-2077 ISSN 0021-9533 R&D Projects: GA ČR GJ15-08835Y; GA MŠk(CZ) LM2015062 Institutional support: RVO:68378050 Keywords : Structured illumination * Image analysis * Chromation * Nucleus * Histone modification * Nuclear pore complexes Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Cell biology Impact factor: 4.431, year: 2016

  16. Electro-organic Nuclear Oxidation: Methoxylation of Aromatic Compounds at Platinum Electrode

    OpenAIRE

    Kumar, Sanjeev

    2011-01-01

    The anodic oxidation of aromatic compounds was carried out at controlled potential in the non aqueous methanol-KOH system for the purpose of investigating this type of anodic reaction as a new possible synthetic method. The electroorganic nuclear oxidation was carried out at controlled potential electrolysis in a conventional three electrode cell assembly with platinum plate working as well as counter electrode and saturated calomel electrode as reference electrode. Controlled potential elect...

  17. The system of sanctions for the illicit trade of nuclear goods

    OpenAIRE

    Colussi, Ilaria Anna

    2015-01-01

    In the area of nuclear non proliferation, the illicit trade of goods that could be used to create nuclear weapons cannot be neglected. Indeed, many States and non-States actors seeking nuclear weapons or wanting to maintain existing nuclear weapons arsenals or capabilities look for obtaining, acquiring and transporting in their own States or locations dual-use technologies, items and materials. This entails a chain of “actors”: (a) the suppliers of goods, (b) a procurement organization, (c) a...

  18. Electro-organic Nuclear Oxidation: Methoxylation of Aromatic Compounds at Platinum Electrode

    Directory of Open Access Journals (Sweden)

    Sanjeev Kumar

    2011-01-01

    Full Text Available The anodic oxidation of aromatic compounds was carried out at controlled potential in the non aqueous methanol-KOH system for the purpose of investigating this type of anodic reaction as a new possible synthetic method. The electroorganic nuclear oxidation was carried out at controlled potential electrolysis in a conventional three electrode cell assembly with platinum plate working as well as counter electrode and saturated calomel electrode as reference electrode. Controlled potential electrolysis was carried out in the solvent methanol and the supporting electrolyte in caustic potash. All the spectral and analytical data were found in good agreement with the synthesized compounds.

  19. N-WASP is required for Amphiphysin-2/BIN1-dependent nuclear positioning and triad organization in skeletal muscle and is involved in the pathophysiology of centronuclear myopathy

    Science.gov (United States)

    Falcone, Sestina; Roman, William; Hnia, Karim; Gache, Vincent; Didier, Nathalie; Lainé, Jeanne; Auradé, Frederic; Marty, Isabelle; Nishino, Ichizo; Charlet-Berguerand, Nicolas; Romero, Norma Beatriz; Marazzi, Giovanna; Sassoon, David; Laporte, Jocelyn; Gomes, Edgar R

    2014-01-01

    Mutations in amphiphysin-2/BIN1, dynamin 2, and myotubularin are associated with centronuclear myopathy (CNM), a muscle disorder characterized by myofibers with atypical central nuclear positioning and abnormal triads. Mis-splicing of amphiphysin-2/BIN1 is also associated with myotonic dystrophy that shares histopathological hallmarks with CNM. How amphiphysin-2 orchestrates nuclear positioning and triad organization and how CNM-associated mutations lead to muscle dysfunction remains elusive. We find that N-WASP interacts with amphiphysin-2 in myofibers and that this interaction and N-WASP distribution are disrupted by amphiphysin-2 CNM mutations. We establish that N-WASP functions downstream of amphiphysin-2 to drive peripheral nuclear positioning and triad organization during myofiber formation. Peripheral nuclear positioning requires microtubule/Map7/Kif5b-dependent distribution of nuclei along the myofiber and is driven by actin and nesprins. In adult myofibers, N-WASP and amphiphysin-2 are only involved in the maintenance of triad organization but not in the maintenance of peripheral nuclear positioning. Importantly, we confirmed that N-WASP distribution is disrupted in CNM and myotonic dystrophy patients. Our results support a role for N-WASP in amphiphysin-2-dependent nuclear positioning and triad organization and in CNM and myotonic dystrophy pathophysiology. PMID:25262827

  20. Maintaining Web Cache Coherency

    Directory of Open Access Journals (Sweden)

    2000-01-01

    Full Text Available Document coherency is a challenging problem for Web caching. Once the documents are cached throughout the Internet, it is often difficult to keep them coherent with the origin document without generating a new traffic that could increase the traffic on the international backbone and overload the popular servers. Several solutions have been proposed to solve this problem, among them two categories have been widely discussed: the strong document coherency and the weak document coherency. The cost and the efficiency of the two categories are still a controversial issue, while in some studies the strong coherency is far too expensive to be used in the Web context, in other studies it could be maintained at a low cost. The accuracy of these analysis is depending very much on how the document updating process is approximated. In this study, we compare some of the coherence methods proposed for Web caching. Among other points, we study the side effects of these methods on the Internet traffic. The ultimate goal is to study the cache behavior under several conditions, which will cover some of the factors that play an important role in the Web cache performance evaluation and quantify their impact on the simulation accuracy. The results presented in this study show indeed some differences in the outcome of the simulation of a Web cache depending on the workload being used, and the probability distribution used to approximate updates on the cached documents. Each experiment shows two case studies that outline the impact of the considered parameter on the performance of the cache.

  1. ADAS Update and Maintainability

    Science.gov (United States)

    Watson, Leela R.

    2010-01-01

    Since 2000, both the National Weather Service Melbourne (NWS MLB) and the Spaceflight Meteorology Group (SMG) have used a local data integration system (LOIS) as part of their forecast and warning operations. The original LOIS was developed by the Applied Meteorology Unit (AMU) in 1998 (Manobianco and Case 1998) and has undergone subsequent improvements. Each has benefited from three-dimensional (3-D) analyses that are delivered to forecasters every 15 minutes across the peninsula of Florida. The intent is to generate products that enhance short-range weather forecasts issued in support of NWS MLB and SMG operational requirements within East Central Florida. The current LDIS uses the Advanced Regional Prediction System (ARPS) Data Analysis System (AD AS) package as its core, which integrates a wide variety of national, regional, and local observational data sets. It assimilates all available real-time data within its domain and is run at a finer spatial and temporal resolution than current national or regional-scale analysis packages. As such, it provides local forecasters with a more comprehensive understanding of evolving fine-scale weather features. Over the years, the LDIS has become problematic to maintain since it depends on AMU-developed shell scripts that were written for an earlier version of the ADAS software. The goals of this task were to update the NWS MLB/SMG LDIS with the latest version of ADAS, incorporate new sources of observational data, and upgrade and modify the AMU-developed shell scripts written to govern the system. In addition, the previously developed ADAS graphical user interface (GUI) was updated. Operationally, these upgrades will result in more accurate depictions of the current local environment to help with short-range weather forecasting applications, while also offering an improved initialization for local versions of the Weather Research and Forecasting (WRF) model used by both groups.

  2. Mechanisms and Kinetics of Organic Aging in High-Level Nuclear Wastes

    International Nuclear Information System (INIS)

    Camaioni, Donald M.; Autrey, S. Thomas; Linehan, John L.

    1999-01-01

    The goal of this project is to develop a fundamental understanding of organic aging and to assemble a model that describes and predicts the thermal and radiolytic aging of organic compounds in high-level wastes (HLW). To reach this goal, we will measure kinetics and elucidate products and mechanisms of organic reactions occurring under conditions of waste storage, retrieval, and processing. Initial emphasis will be placed on studying thermal effects, because organic reaction mechanisms and effects of varying conditions are uncertain, and because we benefit from collaborations with earlier Environmental Management Science Program (EMSP) projects that have worked on radiation effects. Organic complexants are of greatest concern regarding both safety and pretreatment because they have been found to degrade to gases, combust in dry wastes, and interfere with radionuclide separations. Therefore, efforts will focus on studying the reactions of these organic chemicals and associated degradation products. In preliminary work, the authors have used mechanistic kinetic modeling techniques to successfully model the radiolytic degradation of formate to carbonate in HLW simulants. The research will continue development of the model using an iterative process that measures degradation products and kinetics of increasingly complex molecules while adapting the model to reproduce the results each step of the way. Several mechanistic probe experiments have been designed to learn the fundamental mechanisms that operate during thermal degradations so that thermal and radiolytic processes may be integrated within the model. Key kinetic data and thermodynamic properties relating to thermal reactivity will also be acquired so that rate-controlling and product-forming reactions can be predicted. Thermochemical properties of key intermediates will be experimentally and/or theoretically determined to facilitate mechanism verification, structure/reactivity correlation, and prediction of

  3. Development of fauna, micro flora and aquatic organisms database at the vicinity of Gamma Green House in Malaysian Nuclear Agency

    International Nuclear Information System (INIS)

    Nur Humaira Lau Abdullah; Mohd Zaidan Kandar; Phua Choo Kwai Hoe

    2012-01-01

    The biodiversity database of non-human biota which consisted of flora, fauna, aquatic organisms and micro flora at the vicinity of Gamma Greenhouse (GGH) in Malaysian Nuclear Agency is under development. In 2011, a workshop on biodiversity and sampling of flora and fauna by local experts had been conducted in BAB to expose the necessary knowledge to all those involved in this study. Since then, several field surveys had been successfully being carried out covering terrestrial and aquatic ecosystems in order to observe species distribution pattern and to collect the non-human biota samples. The surveys had been conducted according to standard survey procedures and the samples collected were preserved and identified using appropriate techniques. In this paper, the work on fauna, micro flora and aquatic organisms was presented. The fauna and micro flora specimens were kept in Biodiversity Laboratory in Block 44. Based on those field surveys several species of terrestrial vertebrate and invertebrate organisms were spotted. A diverse group of mushroom was found to be present at the study site. The presence of several aquatic zooplankton for example Cyclops, Nauplius; phytoplankton and bacteria for example Klebsiella sp, Enterobacter sp and others in the pond nearby proved that the pond ecosystem is in good condition. Through this study, the preliminary biodiversity list of fauna at the vicinity of the nuclear facility, GGH had been developed and the work will continue for complete baseline data development. Besides that, many principles and methodologies used in ecological survey had been learnt and applied but the skills involved still need to be polished through workshops, collaboration and consultation from local experts. Thus far, several agencies had been approached to gain collaboration and consultation such as Institut Perikanan Malaysia, UKM, UPM and UMT. (author)

  4. Nuclear medicine procedures for the evaluation of male sexual organs: a brief review

    International Nuclear Information System (INIS)

    Bernardo-Filho, Mario; Santos-Filho, Sebastiao David; Fonseca, Adenilson de Souza da; Carter, Kevin; Missailidis, Sotiris

    2008-01-01

    Sexuality consists of three aspects that are interrelated and inseparable, biological, physiological and social. The biological aspect considers the individual's capability to give and to receive pleasure. In consequence, it covers the functionality of the sexual organs and the physiology of human sexual response cycle. Diagnostic imaging modalities, such as single photon emission computed tomography (SPECT) and positron emission tomography (PET) have been used to evaluate clinical disorders of the male reproductive system. PET and SPECT procedures basically involve the administration of a radiopharmaceutical that has a higher uptake in a specific tumor or tissue. The aim of this brief review is to present some radiopharmaceuticals that have been used in the clinical evaluation of the male sexual organs (testes, prostate, seminal vesicles, penis) related with male sexuality. This information could be useful in better understanding the male sexual response cycle, as well as the sexual disorders, when considering the male sexual organs and the pelvic floor. Moreover, the findings obtained with PET and SPECT imaging could help to evaluate the efficacy of clinical results of therapeutic procedures. In conclusion, the knowledge from these images could aid in better understanding the physiology of the different organs related with sexuality. Furthermore, they could be important tools to evaluate the physiological integrity of the involved organs, to improve clinical strategies and to accompany the patients under treatment. (author)

  5. Nuclear medicine procedures for the evaluation of male sexual organs: a brief review

    Energy Technology Data Exchange (ETDEWEB)

    Bernardo-Filho, Mario; Santos-Filho, Sebastiao David; Fonseca, Adenilson de Souza da [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Inst. de Biologia Roberto Alcantara Gomes. Lab. de Radiofarmacia Experimental; Carter, Kevin [Harvard Univ., Boston, MA (United States). Brigham and Women' s Hospital. Dept. of Radiology; Missailidis, Sotiris [The Open University, Milton Keynes (United Kingdom). Dept. of Chemistry and Analytical Sciences

    2008-12-15

    Sexuality consists of three aspects that are interrelated and inseparable, biological, physiological and social. The biological aspect considers the individual's capability to give and to receive pleasure. In consequence, it covers the functionality of the sexual organs and the physiology of human sexual response cycle. Diagnostic imaging modalities, such as single photon emission computed tomography (SPECT) and positron emission tomography (PET) have been used to evaluate clinical disorders of the male reproductive system. PET and SPECT procedures basically involve the administration of a radiopharmaceutical that has a higher uptake in a specific tumor or tissue. The aim of this brief review is to present some radiopharmaceuticals that have been used in the clinical evaluation of the male sexual organs (testes, prostate, seminal vesicles, penis) related with male sexuality. This information could be useful in better understanding the male sexual response cycle, as well as the sexual disorders, when considering the male sexual organs and the pelvic floor. Moreover, the findings obtained with PET and SPECT imaging could help to evaluate the efficacy of clinical results of therapeutic procedures. In conclusion, the knowledge from these images could aid in better understanding the physiology of the different organs related with sexuality. Furthermore, they could be important tools to evaluate the physiological integrity of the involved organs, to improve clinical strategies and to accompany the patients under treatment. (author)

  6. Ergonomics and risk management in high risk organizations: nuclear power plant operator decision making

    International Nuclear Information System (INIS)

    Carvalho, Paulo Victor Rodrigues de

    2003-08-01

    Nuclear power plants are high hazard environments where emergency situations can have devastating effects. The operator crew has the ultimate responsibility to control the energy production process with safety. The outcome of a crisis is consequently dependent on the crew's judgement, decision making and situation awareness. In such way we should know how operators make their decisions in order to develop safety strategies. The aim of this thesis is to examine the cognitive processes through which operators make decisions when dealing with micro incidents during their actual work, and to determine whether they use a naturalistic or normative decision making strategy. That is, do they try to recognize the micro incident as familiar and base decisions on condition-action rules (naturalistic), or do they need to concurrently compare and contrast options before selecting the best possible (normative). The method employed for data collection was the Cognitive Task Analysis (CTA) and Ergonomic Work Analysis (EWA). The main findings of this thesis were that decision making is primarily based on naturalistic strategies, such as condition-action rules and recognition. In new situations rules are created ad hoc. These rules appear derived from experience and training rather than from Standard Operating Procedures and contrast normative competence standards used by nuclear industry. (author)

  7. Catalytic oxidative pyrolysis of spent organic ion exchange resins from nuclear power plants

    International Nuclear Information System (INIS)

    Sathi Sasidharan, N.; Deshingkar, D.S.; Wattal, P.K.; Shirsat, A.N.; Bharadwaj, S.R.

    2005-08-01

    The spent IX resins from nuclear power reactors are highly active solid wastes generated during operations of nuclear reactors. Catalytic oxidative pyrolysis of these resins can lead to high volume reduction of these wastes. Low temperature pyrolysis of transition metal ion loaded IX resins in presence of nitrogen was carried out in order to optimize catalyst composition to achieve maximum weight reduction. Thermo gravimetric analysis of the pyrolysis residues was carried out in presence of air in order to compare the oxidative characteristics of transition metal oxide catalysts. Copper along with iron, chromium and nickel present in the spent IX resins gave the most efficient catalyst combination for catalytic and oxidative pyrolysis of the residues. During low temperature catalytic pyrolysis, 137 Cesium volatility was estimated to be around 0.01% from cationic resins and around 0.1% from anionic resins. During oxidative pyrolysis at 700 degC, nearly 10 to 40% of 137 Cesium was found to be released to off gases depending upon type of resin and catalyst loaded on to it. The oxidation of pyrolytic residues at 700 degC gave weight reduction of 15% for cationic resins and 93% for anionic resins. Catalytic oxidative pyrolysis is attractive for reducing weight and volume of spent cationic resins from PHWRs and VVERs. (author)

  8. Molecular speciation of phosphorus in organic amendments and amended soils using nuclear magnetic resonance and X-ray absorption spectroscopies

    International Nuclear Information System (INIS)

    Ajibove, B.

    2007-01-01

    Characterization of phosphorus (P) in organic amendments is essential for environmentally sustainable fertilization of agricultural soils. The sequential chemical extraction (SCE) technique commonly used for P characterization does not provide any direct molecular information about P species. Studies were conducted to characterize P species in organic amendments and amended soils at a molecular level. The SCE was used to fractionate P in organic amendments including biosolids, hog, dairy and beef cattle manures, and poultry litter. The extracts were analyzed for total P and P species using inductively coupled plasma - optical emission spectroscopy (ICP-OES) and solution 31 P nuclear magnetic resonance (NMR) spectroscopy, respectively. The relative proportions of P species in intact organic amendments and residues after each extraction, and calcareous soils amended with organic amendments and monoammonium phosphate (MAP) were estimated using the synchrotron-based P 1s X-ray absorption near edge structure (XANES) spectroscopy. The solution 31 P NMR provided a detailed characterization of organic P in the non-labile NaOH and HCl fractions of organic amendments, but was limited in characterizing the labile fractions of most of these organic amendments due to their proneness to alkaline hydrolysis. The XANES analysis, however, identified the actual chemical species constituting the labile P that was only characterized as inorganic P or orthophosphates by sequential extraction and solution 31 P NMR. In the amended Vertisolic and Chernozemic soils, XANES analysis estimated 'soluble and adsorbed P' as the dominant P species. For the Vertisolic soil, both the unamended and soil amended with biosolids and MAP contained hydroxyapatite (HAP). In addition, soil amended with biosolids, hog and dairy manures contained β-tricalcium phosphate (TRICAL), a more soluble CaP than HAP. TRICAL was found in all amended soils except in that amended with hog manure, while HAP was present

  9. A fractal model for nuclear organization: current evidence and biological implications

    Science.gov (United States)

    Bancaud, Aurélien; Lavelle, Christophe; Huet, Sébastien; Ellenberg, Jan

    2012-01-01

    Chromatin is a multiscale structure on which transcription, replication, recombination and repair of the genome occur. To fully understand any of these processes at the molecular level under physiological conditions, a clear picture of the polymorphic and dynamic organization of chromatin in the eukaryotic nucleus is required. Recent studies indicate that a fractal model of chromatin architecture is consistent with both the reaction-diffusion properties of chromatin interacting proteins and with structural data on chromatin interminglement. In this study, we provide a critical overview of the experimental evidence that support a fractal organization of chromatin. On this basis, we discuss the functional implications of a fractal chromatin model for biological processes and propose future experiments to probe chromatin organization further that should allow to strongly support or invalidate the fractal hypothesis. PMID:22790985

  10. Survey on current status of international organizations and foreign countries for emergency preparedness and response and consider technical issues on guideline for nuclear emergency preparedness

    International Nuclear Information System (INIS)

    Kimura, Masanori; Ishikawa, Jun; Homma, Toshimitsu; Sato, Sohei

    2010-06-01

    This review report describes survey results on current status of nuclear emergency preparedness and response in international organizations such as ICRP and IAEA, and consideration results of technical issues on the 'Guideline for Nuclear Emergency Preparedness' issued by the Nuclear Safety Commission of Japan (NSC). First, we summarized the following points. The principle of intervention for protection of the public in radiological emergency indicated by ICRP recommendations. The basic concept on nuclear emergency preparedness and response shown by IAEA Safety Standard Series. Next, we considered technical issues on the guideline, such as basic requirements for nuclear emergency preparedness and response, development of EPZ, intervention level for protective measurement, decision criteria for selecting the proper protective action measurement and concept for the support system of experts, based on these survey results. In order to respond to nuclear emergency more effectively in Japan, the guideline should show the basic concept of nuclear emergency preparedness and response for the period between the beginning of the nuclear emergency and the termination of early protective actions. Then, it is important to develop the method of the threat assessment for nuclear facilities, emergency action level (EAL) for the emergency classification, the range of precautionary action zone (PAZ) and urgent protective action planning zone (UPZ) in emergency planning phase, and the basic concept on the implement of protective measurements and operational intervention level (OIL) in emergency response phase. (author)

  11. Decision no. 2011-DC-0215 of the French nuclear safety authority from May 5, 2011, ordering ITER Organization to proceed to a complementary safety evaluation of its basic nuclear facility in the eyes of the Fukushima Daiichi nuclear power plant accident

    International Nuclear Information System (INIS)

    2011-01-01

    As a consequence of the accident of the Fukushima Daiichi nuclear power plant (Japan), the French Prime Minister entrusted the French nuclear safety authority (ASN) with the mission to carry out a safety analysis re-evaluation of the French nuclear facilities, and in particular the nuclear power plants. A decision has been addressed by the ASN to each nuclear operator with the specifications of this safety re-evaluation analysis and the list of facilities in concern. This document is the decision addressed to the ITER Organization, operator of the ITER tokamak facility of Cadarache (France). (J.S.)

  12. Updating of the fire fighting systems and organization at the Embalse nuclear power plant, Argentina

    International Nuclear Information System (INIS)

    Acevedo, C.F.

    1998-01-01

    A brief description is given of the updating carried out at the Embalse NPP after commissioning, covering the station fire equivalent loads, the station weak points from the fire point of view, the possible upgrading of systems or technological improvements, early alarm and automatic actions, organizations, education and training, and drills. (author)

  13. U.S. Nuclear Regulatory Commission organization charts and functional statements. Revision 18

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-23

    This document (NUREG-0325) is the current US NRC organization chart, listing all NRC offices and regions and their components down through the branch level as of July 23, 1995. Functional statements of each position are given, as is the name of the individual holding the position.

  14. U.S. Nuclear Regulatory Commission organization charts and functional statements. Revision 18

    International Nuclear Information System (INIS)

    1995-01-01

    This document (NUREG-0325) is the current US NRC organization chart, listing all NRC offices and regions and their components down through the branch level as of July 23, 1995. Functional statements of each position are given, as is the name of the individual holding the position

  15. Causal model of safety-checking action of the staff of nuclear power plants and the organization climate

    International Nuclear Information System (INIS)

    Fukui, Hirokazu; Yoshida, Michio; Yamaura, Kazuho

    2000-01-01

    For those who run an organization, it is critical to identify the causal relationship between the organization's characteristics and the safety-checking action of its staff, in order to effectively implement activities for promoting safety. In this research. a causal model of the safety-checking action was developed and factors affecting it were studied. A questionnaire survey, which includes safety awareness, attitude toward safety, safety culture and others, was conducted at three nuclear power plants and eight factors were extracted by means of factor analysis of the questionnaire items. The extracted eight interrelated factors were as follows: work norm, supervisory action, interest in training, recognition of importance, safety-checking action, the subject of safety, knowledge/skills, and the attitude of an organization. Among them, seven factors except the recognition of importance were defined as latent variables and a causal model of safety-checking action was constructed. By means of covariance structure analysis, it was found that the three factors: the attitude of an organization, supervisory action and the subject of safety, have a significant effect on the safety-checking action. Moreover, it was also studied that workplaces in which these three factors are highly regarded form social environment where safety-checking action is fully supported by the workplace as a whole, while workplaces in which these three factors are poorly regarded do not fully form social environment where safety-checking action is supported. Therefore, the workplaces form an organizational environment where safety-checking action tends to depend strongly upon the knowledge or skills of individuals. On top of these, it was noted that the attitude of an organization and supervisory action are important factors that serve as the first trigger affecting the formation of the organizational climate for safety. (author)

  16. Organization and management of heterogeneous, dispersed data bases in nuclear engineering

    International Nuclear Information System (INIS)

    Eastman, C.M.

    1986-01-01

    Large, complex, multiperson engineering projects in many areas, nuclear, aerospace, electronics, and manufacturing, have inherent needs for coordination, control, and management of the related engineering data. Taken in the abstract, the notion of an integrated engineering data base (IED) for such projects is attractive. The potential capabilities of an (IED) are that all data are managed in a coordinated way, are made accessible to all users who need it, allow relations between all parts of the data to be tracked and managed, provide backup, recovery, audit trails, security and access control, and allow overall project status to be monitored and managed. Common data accessing schemes and user interfaces to applications are also part of an IED. This paper describes a new software product that allows incremental realization of many of the capabilities of an IED, without the massive disruption and risk

  17. Uranium oxide catalysts: environmental applications for treatment of chlorinated organic waste from nuclear industry.

    Science.gov (United States)

    Lazareva, Svetlana; Ismagilov, Zinfer; Kuznetsov, Vadim; Shikina, Nadezhda; Kerzhentsev, Mikhail

    2018-02-05

    Huge amounts of nuclear waste, including depleted uranium, significantly contribute to the adverse environmental situation throughout the world. An approach to the effective use of uranium oxides in catalysts for the deep oxidation of chlorine-containing hydrocarbons is suggested. Investigation of the catalytic activity of the synthesized supported uranium oxide catalysts doped with Cr, Mn and Co transition metals in the chlorobenzene oxidation showed that these catalysts are comparable with conventional commercial ones. Physicochemical properties of the catalysts were studied by X-ray diffraction, temperature-programmed reduction with hydrogen (H 2 -TPR), and Fourier transform infrared spectroscopy. The higher activity of Mn- and Co-containing uranium oxide catalysts in the H 2 -TPR and oxidation of chlorobenzene in comparison with non-uranium catalysts may be related to the formation of a new disperse phase represented by uranates. The study of chlorobenzene adsorption revealed that the surface oxygen is involved in the catalytic process.

  18. Assessment of safety culture from the INB organization: A case study for nuclear fuel cycle industry

    International Nuclear Information System (INIS)

    Goncalves, J.S.; Barreto, A.C.

    2002-01-01

    The present article describes strategies, methodologies and first results on the Safety Culture Self-assessment Project under way at INB since August 2001. As a Brazilian Government company in charge of the nuclear fuel cycle activities,. the main purposes of the Project is to evaluate the present status of its safety culture and to propose actions to ensure continuous safety improvement at management level of its industrial processes. The proposed safety culture assessment describes INB's various production sites taking into account the different aspects of their activities, such as regional, social and technical issues. The survey was performed in March/2002 very good attendance (about 80%) the employees. The first global survey results are presented in item 4. (author)

  19. Observation of nuclear track in organic material by atomic force microscopy in real time during etching

    CERN Document Server

    Palmino, F; Labrune, J C

    1999-01-01

    The developments of Atomic Force Microscopy (AFM) allow to investigated solid surfaces with a nanometer scale. These techniques are useful methods allowing direct observation of surface morphologies. Particularly in the nuclear track fields, they offer a new tool to give many new informations on track formation. In this paper we present the preliminary results of a new use of this technique to characterize continuously the formation of the revealed track in a cellulose nitrate detector (LR115) after an alpha particle irradiation. For that, a specific cell has been used to observe, by nano-observations, the evolution of track shapes simultaneously with chemical treatment. Thus, the track shape evolution has been studied; visualizing the evolution of the tracks in real time, in situ during the chemical etching process.

  20. N-WASP is required for Amphiphysin-2/BIN1-dependent nuclear positioning and triad organization in skeletal muscle and is involved in the pathophysiology of centronuclear myopathy

    OpenAIRE

    Falcone, Sestina; Roman, William; Hnia, Karim; Gache, Vincent; Didier, Nathalie; Lainé, Jeanne; Auradé, Frederic; Marty, Isabelle; Nishino, Ichizo; Charlet-Berguerand, Nicolas; Romero, Norma Beatriz; Marazzi, Giovanna; Sassoon, David; Laporte, Jocelyn; Gomes, Edgar R

    2014-01-01

    Mutations in amphiphysin-2/BIN1, dynamin 2, and myotubularin are associated with centronuclear myopathy (CNM), a muscle disorder characterized by myofibers with atypical central nuclear positioning and abnormal triads. Mis-splicing of amphiphysin-2/BIN1 is also associated with myotonic dystrophy that shares histopathological hallmarks with CNM. How amphiphysin-2 orchestrates nuclear positioning and triad organization and how CNM-associated mutations lead to muscle dysfunction remains elusive....

  1. Synthesis of organic liquids/geo-polymer composites for the immobilization of nuclear wastes

    International Nuclear Information System (INIS)

    Cantarel, Vincent

    2016-01-01

    This work is included in the management of radioactive organic liquids research field. The process is based on an emulsification of organic liquid in an alkali silicate solution allowing the synthesis of a geo-polymer matrix. The first part of this work consists in carrying out a screening on different organic liquids. A model system representative of the various oils and a geo-polymer reference formulation are then defined. The second part deals with the structuration of the organic liquid/geo-polymer structuration, from the mixture of the reactants to the final material. It aims at determining the phenomena allowing the synthesis of a homogeneous composite. The last two parts aim at characterizing the composite by studying its structure (chemical structure, porosity of the geo-polymer and dispersion of the oil) and its properties with respect to the application to the immobilization of radioactive waste. Unlike calcium silicate-based cementitious matrices, the structure of the geo-polymer is not affected by the chemical nature of the organic liquids. Only acid oils inhibit or slow down the geo-polymerization reaction. In order to obtain a homogeneous material, the presence of surfactant molecules is necessary. The emulsion stabilization mechanism at the base of the process is relying on a synergy between the surfactant molecules and the aluminosilicate particles present in the geo-polymer paste. The kinetics (chemical and mechanical) of the geo-polymerization are not impacted by the presence of oil or surfactants. Only an increase in the viscoelastic moduli and the elastic character of the pastes can be observed. This difference in rheological behavior is mainly due to the presence of surfactant. The structure of the matrix is identical to that of a pure geo-polymer of the same formulation. The organic liquid is dispersed in spherical inclusions whose radius is between 5 and 15 μm. These droplets are separated from each other, and from the environment by the

  2. Cognitive decision errors and organization vulnerabilities in nuclear power plant safety management: Modeling using the TOGA meta-theory framework

    Energy Technology Data Exchange (ETDEWEB)

    Cappelli, M. [UTFISST, ENEA Casaccia, via Anguillarese 301, Rome (Italy); Gadomski, A. M. [ECONA, Centro Interuniversitario Elaborazione Cognitiva Sistemi Naturali e Artificiali, via dei Marsi 47, Rome (Italy); Sepiellis, M. [UTFISST, ENEA Casaccia, via Anguillarese 301, Rome (Italy); Wronikowska, M. W. [UTFISST, ENEA Casaccia, via Anguillarese 301, Rome (Italy); Poznan School of Social Sciences (Poland)

    2012-07-01

    In the field of nuclear power plant (NPP) safety modeling, the perception of the role of socio-cognitive engineering (SCE) is continuously increasing. Today, the focus is especially on the identification of human and organization decisional errors caused by operators and managers under high-risk conditions, as evident by analyzing reports on nuclear incidents occurred in the past. At present, the engineering and social safety requirements need to enlarge their domain of interest in such a way to include all possible losses generating events that could be the consequences of an abnormal state of a NPP. Socio-cognitive modeling of Integrated Nuclear Safety Management (INSM) using the TOGA meta-theory has been discussed during the ICCAP 2011 Conference. In this paper, more detailed aspects of the cognitive decision-making and its possible human errors and organizational vulnerability are presented. The formal TOGA-based network model for cognitive decision-making enables to indicate and analyze nodes and arcs in which plant operators and managers errors may appear. The TOGA's multi-level IPK (Information, Preferences, Knowledge) model of abstract intelligent agents (AIAs) is applied. In the NPP context, super-safety approach is also discussed, by taking under consideration unexpected events and managing them from a systemic perspective. As the nature of human errors depends on the specific properties of the decision-maker and the decisional context of operation, a classification of decision-making using IPK is suggested. Several types of initial situations of decision-making useful for the diagnosis of NPP operators and managers errors are considered. The developed models can be used as a basis for applications to NPP educational or engineering simulators to be used for training the NPP executive staff. (authors)

  3. Cognitive decision errors and organization vulnerabilities in nuclear power plant safety management: Modeling using the TOGA meta-theory framework

    International Nuclear Information System (INIS)

    Cappelli, M.; Gadomski, A. M.; Sepiellis, M.; Wronikowska, M. W.

    2012-01-01

    In the field of nuclear power plant (NPP) safety modeling, the perception of the role of socio-cognitive engineering (SCE) is continuously increasing. Today, the focus is especially on the identification of human and organization decisional errors caused by operators and managers under high-risk conditions, as evident by analyzing reports on nuclear incidents occurred in the past. At present, the engineering and social safety requirements need to enlarge their domain of interest in such a way to include all possible losses generating events that could be the consequences of an abnormal state of a NPP. Socio-cognitive modeling of Integrated Nuclear Safety Management (INSM) using the TOGA meta-theory has been discussed during the ICCAP 2011 Conference. In this paper, more detailed aspects of the cognitive decision-making and its possible human errors and organizational vulnerability are presented. The formal TOGA-based network model for cognitive decision-making enables to indicate and analyze nodes and arcs in which plant operators and managers errors may appear. The TOGA's multi-level IPK (Information, Preferences, Knowledge) model of abstract intelligent agents (AIAs) is applied. In the NPP context, super-safety approach is also discussed, by taking under consideration unexpected events and managing them from a systemic perspective. As the nature of human errors depends on the specific properties of the decision-maker and the decisional context of operation, a classification of decision-making using IPK is suggested. Several types of initial situations of decision-making useful for the diagnosis of NPP operators and managers errors are considered. The developed models can be used as a basis for applications to NPP educational or engineering simulators to be used for training the NPP executive staff. (authors)

  4. Global nuclear security engagement

    International Nuclear Information System (INIS)

    Kulp, W.D. III

    2012-01-01

    Full text: The Nuclear Security Summits in Washington (2010) and Seoul (2012) were convened with the goal of reducing the threat of nuclear terrorism. These meetings have engaged States with established nuclear fuel cycle activities and encouraged their commitment to nuclear security. The participating States have reaffirmed that it is a fundamental responsibility of nations to maintain effective nuclear security in order to prevent unauthorized actors from acquiring nuclear materials. To that end, the participants have identified important areas for improvement and have committed to further progress. Yet, a broader message has emerged from the Summits: effective nuclear security requires both global and regional engagement. Universal commitment to domestic nuclear security is essential, if only because the peaceful use of nuclear energy remains a right of all States: Nations may someday adopt nuclear energy, even if they are not currently developing nuclear technology. However, the need for nuclear security extends beyond domestic power production. To harvest natural resources and to develop part of a nuclear fuel cycle, a State should embrace a nuclear security culture. Nuclear materials may be used to produce isotopes for medicine and industry. These materials are transported worldwide, potentially crossing a nation's borders or passing by its shores. Regrettably, measures to prevent the loss of control may not be sufficient against an adversary committed to using nuclear or other radioactive materials for malicious acts. Nuclear security extends beyond prevention measures, encompassing efforts to detect illicit activities and respond to nuclear emergencies. The Seoul Communique introduces the concept of a Global Nuclear Security Architecture, which includes multilateral instruments, national legislation, best practices, and review mechanisms to promote adoption of these components. Key multilateral instruments include the Convention on Physical Protection of

  5. An empirical analysis of nuclear power plant organization and its effect on safety performance

    International Nuclear Information System (INIS)

    Thurber, J.A.

    1985-01-01

    The paper documents work performed on three tasks. The first task concerned the creation of measures of organizational structure. An earlier review of the literature supported the position that organizational structure (e.g., the way the work of the organization is divided, administered, and coordinated) is a likely determinant of plant safety performance. While data were not available on some salient dimensions of organizational structure, Final Safety Analysis Reports (FSARs), Technical Specifications, and a survey of plant technical resources allowed for measurement on three primary dimensions. These are the vertical structure of the plant (e.g., the number of ranks and the ratio of supervisors to subordinates), the horizontal structure of the plant (e.g., the way the organization is divided into administrative and work units), and the coordinative structure of the plant (e.g., the ways that work units are linked)

  6. Patterns identification in supervisory systems of nuclear reactors installations and gas pipelines systems using self-organizing maps

    International Nuclear Information System (INIS)

    Doraskevicius Junior, Waldemar

    2005-01-01

    Self-Organizing Maps, SOM, of Kohonen were studied, implemented and tested with the aim of developing, for the energy branch, an effective tool especially for transient identification in nuclear reactors and for gas pipelines networks logistic supervision, by classifying operations and identifying transients or abnormalities. The digital system for the test was developed in Java platform, for the portability and scalability, and for belonging to free development platforms. The system, executed in personal computers, showed satisfactory results to aid in decision taking, by classifying IRIS (International Reactor Innovative and Secure) reactor operation conditions (data from simulator) and by classifying Southeast (owner: TRANSPETRO - Brazil) gas pipeline network. Various adaptations were needed for such business, as new topologies for the output layer of artificial neural network and particular preparation for the input data. (author)

  7. Objectives, Extent and Organization of Radiological and Environmental Protection in Relation to the Nature and Size of Nuclear Facilities

    International Nuclear Information System (INIS)

    Kathren, R.L.

    1979-01-01

    Radiological and environmental protection programs for nuclear facilities have similar goals and objectives, which are basically to protect people and the environment from adverse effects. To be effective, the programs must have organizational independence and a strong commitment from management. In return, the programs should ensure that the facility is operating in full compliance with law and good practice. The scope and elements of radiological environmental protection programs will vary according to facility type and size, with the larger and more complex facilities having a diversity of staff and functions. Examples of good and poor organization charts are given and discussed from the standpoint of program effectiveness along with a discussion of the role of the radiation protection committee. (author)

  8. Implementation of manufacturing data management application in the scientific research project. Case: CERN, the European Organization for Nuclear Research

    CERN Document Server

    Saifoulina, Margarita

    2010-01-01

    This Bachelor’s thesis examined the implementation process of an MTF (Manufacturing and Test Folder) application in the CLIC (Compact Linear Collider) Radio Frequency Structure Development project for manufacturing data management purposes. The primary goal of the study was to investigate how MTF implementation and its integration with CERN EDMS (Engineering and Equipment Data Management System) system could facilitate product life cycle through the supply chain, and could affect on manufacturing operations performance in internaland external levels. The aim of the study was also to find out implementation differences within CERN (European Organization for Nuclear Research) projects. The study is divided into two parts: a qualitative theory section and an empirical section. In the theory section differences of features between PDM (Product Data Management), EDM (Engineering Data Management) and PLM (Product Life Cycle Management) systems were studied. The thesis examined the benefits and managerial challeng...

  9. evaluation of selected composted organic sources on potato plant grown in sandy soil using nuclear technique

    International Nuclear Information System (INIS)

    Moursy, A.A.A.

    2008-01-01

    the main point of this study is the evaluation of organic compost as a source of nutrient demand by potatoes cultivated in light texture soil under drip irrigation system. the composted materials either applied alone or in combination with mineral fertilizer have an effective role on potato yields and nutrients management under field scale. so, many objectives were achieved. the valuable results obtained in the present study could be summarized as follows: part one: composting experiment contains ph changes of composted materials, EC changes with time, nitrogen content in composted materials, change of c/n ratio with time, organic matter content of the composted materials, phosphorus content in composted materials,. part two: potato field experiment contains .dry matter yield, tuber dry weight, tuber yield, nutrients uptake by potato varieties,. part three contains . application of 15 N isotope dilution technique, nitrogen derived from fertilizer (Ndff), nitrogen derived from organic compost (% Ndf comp),nitrogen derived from soil (% Ndfs), fertilizer use efficiency (% FUE), 15 N recovered by potatoes.

  10. Quantification of organic acids in beer by nuclear magnetic resonance (NMR)-based methods

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues, J.E.A. [CICECO-Department of Chemistry, University of Aveiro, Campus de Santiago, 3810-193 Aveiro (Portugal); Erny, G.L. [CESAM - Department of Chemistry, University of Aveiro, Campus de Santiago, 3810-193 Aveiro (Portugal); Barros, A.S. [QOPNAA-Department of Chemistry, University of Aveiro, Campus de Santiago, 3810-193 Aveiro (Portugal); Esteves, V.I. [CESAM - Department of Chemistry, University of Aveiro, Campus de Santiago, 3810-193 Aveiro (Portugal); Brandao, T.; Ferreira, A.A. [UNICER, Bebidas de Portugal, Leca do Balio, 4466-955 S. Mamede de Infesta (Portugal); Cabrita, E. [Department of Chemistry, New University of Lisbon, 2825-114 Caparica (Portugal); Gil, A.M., E-mail: agil@ua.pt [CICECO-Department of Chemistry, University of Aveiro, Campus de Santiago, 3810-193 Aveiro (Portugal)

    2010-08-03

    The organic acids present in beer provide important information on the product's quality and history, determining organoleptic properties and being useful indicators of fermentation performance. NMR spectroscopy may be used for rapid quantification of organic acids in beer and different NMR-based methodologies are hereby compared for the six main acids found in beer (acetic, citric, lactic, malic, pyruvic and succinic). The use of partial least squares (PLS) regression enables faster quantification, compared to traditional integration methods, and the performance of PLS models built using different reference methods (capillary electrophoresis (CE), both with direct and indirect UV detection, and enzymatic essays) was investigated. The best multivariate models were obtained using CE/indirect detection and enzymatic essays as reference and their response was compared with NMR integration, either using an internal reference or an electrical reference signal (Electronic REference To access In vivo Concentrations, ERETIC). NMR integration results generally agree with those obtained by PLS, with some overestimation for malic and pyruvic acids, probably due to peak overlap and subsequent integral errors, and an apparent relative underestimation for citric acid. Overall, these results make the PLS-NMR method an interesting choice for organic acid quantification in beer.

  11. Assessing optimal software architecture maintainability

    NARCIS (Netherlands)

    Bosch, Jan; Bengtsson, P.O.; Smedinga, Rein; Sousa, P; Ebert, J

    2000-01-01

    Over the last decade, several authors have studied the maintainability of software architectures. In particular, the assessment of maintainability has received attention. However, even when one has a quantitative assessment of the maintainability of a software architecture, one still does not have

  12. Nuclear information services at the National Nuclear Data Center

    International Nuclear Information System (INIS)

    Burrows, T.W.; Tuli, J.K.

    1996-01-01

    The numeric and bibliographic nuclear data bases maintained by the National Nuclear Data Center and access to these data bases will be described. The U.S. Nuclear Data and Reaction Data Networks will also be briefly described

  13. Self-organization in the nuclear system: Pt. 2; Formation of a new order

    Energy Technology Data Exchange (ETDEWEB)

    Iskra, W. (Forschungszentrum Rossendorf e.V. (FZR), Dresden (Germany) Soltan Inst. for Nuclear Studies, Otwock-Swierk (Poland)); Mueller, M. (Forschungszentrum Rossendorf e.V. (FZR), Dresden (Germany)); Rotter, I. (Forschungszentrum Rossendorf e.V. (FZR), Dresden (Germany) Technische Univ., Dresden (Germany). Inst. fuer Theoretische Physik)

    1994-05-01

    The information entropy of the atomic nucleus is calculated from the wavefunctions of the resonance states. The transition from low- to high-level density is traced as a function of the coupling strength between the discrete nuclear states and the environment of decay channels. In the critical region of the coupling strength where a redistribution inside the nucleus takes place, information entropy in relation to the discrete states of the closed system is created. Beyond the critical value, a few relevant short-lived modes exist together with long-lived noise. This result is in full correspondence to the maximum information entropy principle of synergetics formulated by Haken. The noise is characterized by disorder expressed by a large information entropy while the relevant modes have a high order and take, correspondingly, a small part of the information entropy of the whole system. The entropy excess accompanying the formation of the new order is used inside the system for creation of noise. Further, the noise is not structureless and the corresponding information entropy is smaller than its maximal value. (Author).

  14. On the fallout by nuclear explosion experiment and the radioactive iodine in animal organism

    International Nuclear Information System (INIS)

    Tanaka, Giichiro

    1974-01-01

    Radioactive iodine (mainly 131 I, 132 I, 133 I, and 135 I) was measured with fallout, cow milk, human urine, and thyroid glands (human and cattles) after the first nuclear explosion experiment in China. Analysing method was determined by placing emphasis on rapidity and perfect separation from other nuclides. The detectable limit employing this method was about several p Ci. The identification of radioactive iodine was performed with a simultaneous counting type β - ray spectrometer, and 131 I, 132 I, and 133 I were identified by their half lives. 131 I in cow milk increased from around the 4th day after the experiment, and it had been detected for a month continuously, the maximum amount being 437 p Ci/l. In thyroid glands, 131 I was detected for 100 days in a milch cow, the maximum being 88, 1p Ci/g, while it was somewhat low in Japanese cows and pigs. 131 I in the thyroid gland of a human infant (accidentally died after 12 days) was 1.29p Ci/g. 131 I in human urine was 6.3p Ci/l on the 7th day. (Kobatake, H.)

  15. Impact of vaccine therapy using nuclear histone H1 on allograft survival in experimental organ transplantation.

    Science.gov (United States)

    Nakano, Toshiaki; Goto, Shigeru; Lai, Chia-Yun; Hsu, Li-Wen; Ono, Kazuhisa; Kawamoto, Seiji; Lin, Yu-Chun; Kao, Ying-Hsien; Chiang, Kuei-Chen; Ohmori, Naoya; Goto, Takeshi; Sato, Shuji; Tu, Chieh-Hsien; Jawan, Bruno; Cheng, Yu-Fan; Chen, Chao-Long

    2007-04-01

    We recently reported that autoreactive antibody (Ab) against nuclear histone H1 had been identified as an immunosuppressive factor in a rat tolerogenic orthotopic liver transplantation (OLT) model. The present study aimed to determine whether the up-regulation of antihistone H1 Ab by histone H1 vaccination leads to tolerance. Histone H1-immunized rats were established by intraperitoneal vaccination with histone H1 at every two-weekly interval. By using mixed lymphocyte reaction (MLR) and heterotopic heart transplantation (HHT), the alloreactive T cell response and allograft survival of histone H1-immunized rats were compared with those of control rats. Cytokine and cellular profiles in histone H1-immunized rats were determined by reverse transcriptase polymerase chain reaction (RT-PCR), enzyme-linked immunosorbent assay (ELISA) and flow cytometry. Immunization with histone H1 in Freund's adjuvant induced alloreactive T cell unresponsiveness and prolonged heterotopic heart allograft survival. It also down-regulated the expression of major histocompatibility complex (MHC) class II and CD25 on splenic cells, elevated the T helper cell type 2 (Th2) skewing index (Interleukin (IL)-4/interferon (IFN)-gamma ratio or IL-4/IL-2 ratio) and modified the serum cytokine profiles. The present results suggest that histone H1 vaccination of transplant recipients, which leads to the production of immunosuppressive factor and the modification of the cytokine/cellular profiles, has great potential as a tolerance therapy for prospective transplantation.

  16. Study of the dose received by the population living in the surroundings of Nuclear Power Station, by the Polonium 210 incorporated through the consumption of sea organisms

    International Nuclear Information System (INIS)

    Avila, R.; Alonso, C.; Batista, M.

    1993-01-01

    As part of the study of the doses received by the population in the surrounding of Juragua Nuclear Power Station, now under construction, it was determined the amount of Po-210 in the doses for the consumption of sea organisms. In the zone comprising 30 Km around the Nuclear Power Station, two populations were chosen for the study: the city of Cienfuegos- with a higher number of inhabitants in the zone- and the village know as Castillo de Jagua- where a higher number of sea organism is consumed

  17. Effective citizen advocacy of beneficial nuclear technologies

    International Nuclear Information System (INIS)

    McKibben, J. Malvyn; Wood, Susan

    2007-01-01

    In 1991, a small group of citizens from communities near the Savannah River Site (SRS) formed a pro-nuclear education and advocacy group, Citizens for Nuclear Technology Awareness (CNTA). Their purpose was to: (1) counter nuclear misinformation that dominated the nation's news outlets, (2) provide education on nuclear subjects to area citizens, students, elected officials, and (3) provide informed citizen support for potential new missions for SRS when needed. To effectively accomplish these objectives it is also essential to establish and maintain good relations with community leaders and reporters that cover energy and nuclear subjects. The organization has grown considerably since its inception and has expanded its sphere of influence. We believe that our experiences over these fifteen years are a good model for effectively communicating nuclear subjects with the public. This paper describes the structure, operation and some of the results of CNTA. (authors)

  18. Chaos-driven decay of nuclear giant resonances: Quantum route to self-organization

    International Nuclear Information System (INIS)

    Drozdz, S.; Nishizaki, S.; Wambach, J.

    1994-01-01

    The influence of background states with increasing level of complexity on the strength distribution of the isoscalar and isovector giant quadrupole resonance in 40 Ca is studied. It is found that the background characteristics, typical for chaotic systems, strongly affect the fluctuation properties of the strength distribution. In particular, the small components of the wave function obey a scaling law analogous to self-organized systems at the critical state. This appears to be consistent with the Porter-Thomas distribution of the transition strength

  19. Safe organization of nuclear phase-out. Why Germany needs nuclear competence for dismantling, reactor safety, final waste storage and radiation protection

    International Nuclear Information System (INIS)

    2011-01-01

    As a consequence of the catastrophic accidents in Fukushima Daiichi Germany is the first industrial country in the world that decided the nuclear phase- out within the next decade. This decision implies that the operation of the remaining nuclear power plants has to be performed according to the highest safety standards. Apart from that the dismantling of the decommissioned nuclear power plants and the still not resolved radioactive waste disposal will keep the society in action for the next decades. The book covers the actual status with respect to the need of nuclear competence to cope with the mentioned challenges. [de

  20. Vanadium in organic fossils as determined by nuclear-physical methods of analysis

    International Nuclear Information System (INIS)

    Nadirov, N.N.; Solodukhin, V.P.

    1998-01-01

    Results are presented of several year investigation to study possibilities of the NPMA for the determination of vanadium in organic fossils and applications of these methods to scientific and practical tasks. For these purposes, various versions of activation analysis (AA), X-ray fluorescence analysis (XRFA), electron spin resonance (ESR) spectroscopy and atomic emission with inductively coupled plasma spectroscopy (AES-ICP). Advantages and pitfalls of individual methods are discussed. The techniques developed can be used for estimation and calculation of stocks of vanadium in organic fossils at the territories of Kazakstan, Tatarstan and along the Volga-river. Analysis results helped in discovering new, industrially important deposits of this valuable metal. Quantitative determination of vanadium was carried out at different stages of technological processes of its extraction from high-viscous oils and oil-bitumen rocks. Results of analyses allowed to reveal the most effective versions of technologies of demetallization of these fossils. Content of vanadium was also studied in different locations of high-viscous oil deposits being explored by the method of inside-stratum burning. Results of analyses showed that the concentration of vanadium in oil decreases considerably with increasing temperature, that is, a considerable part of vanadium (up to 60 percent) may be lost irretrievably. Thus, for the exploration of these deposits a method of vapor-thermal influence onto the stratum was recommended, by using of which the loss of vanadium is insignificant

  1. EVALUATED NUCLEAR STRUCTURE DATA FILE. A MANUAL FOR PREPARATION OF DATA SETS

    International Nuclear Information System (INIS)

    TULI, J.K.

    2001-01-01

    This manual describes the organization and structure of the Evaluated Nuclear Structure Data File (ENSDF). This computer-based file is maintained by the National Nuclear Data Center (NNDC) at Brookhaven National Laboratory for the international Nuclear Structure and Decay Data Network. For every mass number (presently, A ≤ 293), the Evaluated Nuclear Structure Data File (ENSDF) contains evaluated structure information. For masses A ≥ 44, this information is published in the Nuclear Data Sheets; for A < 44, ENSDF is based on compilations published in the journal Nuclear Physics. The information in ENSDF is updated by mass chain or by nuclide with a varying cycle time dependent on the availability of new information

  2. Nuclear power plants

    International Nuclear Information System (INIS)

    1985-01-01

    Data concerning the existing nuclear power plants in the world are presented. The data was retrieved from the SIEN (Nuclear and Energetic Information System) data bank. The information are organized in table forms as follows: nuclear plants, its status and type; installed nuclear power plants by country; nuclear power plants under construction by country; planned nuclear power plants by country; cancelled nuclear power plants by country; shut-down nuclear power plants by country. (E.G.) [pt

  3. Improving performance of high risk organizations Spanish nuclear sector from the analysis of organizational culture factors; Mejora del desempeno de las organizaciones de alto riesgo del sector nuclear espanol a partir del analisis de los factores de cultura organizativa

    Energy Technology Data Exchange (ETDEWEB)

    La Salabarnada, E.; German, S.; Silla, I.; Navajas, J.

    2012-07-01

    This paper presents the research project funded by UNESA and conducted by the CISOT-CIEMAT that aims to contribute to improving the operating performance of the Spanish nuclear power plants. This paper aims to identify the factors and key organizational processes to improve efficiency, in order to advance knowledge about the influence of organizational culture on the safety of high reliability organizations.

  4. Organ dose assessment of nuclear medicine practitioners using L-block shielding device for handing diagnostic radioisotopes

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Se Sik; Kim, Jung Hoon [Dep. of Radiological Science, College of Health Science, Catholic University of Pusan, Busan (Korea, Republic of); Cho, Yong In [Dept. of Diagnostic Radiology, Dongnam Institute of Radiological and Medical Science, Busan (Korea, Republic of)

    2017-03-15

    In the case of nuclear medicine practitioners in medical institutions, a wide range of exposure dose to individual workers can be found, depending on the type of source, the amount of radioactivity, and the use of shielding devices in handling radioactive isotopes. In this regard, this study evaluated the organ dose on practitioners as well as the dose reduction effect of the L-block shielding device in handling the diagnostic radiation source through the simulation based on the Monte Carlo method. As a result, the distribution of organ dose was found to be higher as the position of the radiation source was closer to the handling position of a practitioner, and the effective dose distribution was different according to the ICRP tissue weight. Furthermore, the dose reduction effect according to the L-block thickness tended to decrease, which showed the exponential distribution, as the shielding thickness increased. The dose reduction effect according to each radiation source showed a low shielding effect in proportion to the emitted gamma ray energy level.

  5. Educational Programme in Nuclear Security

    International Nuclear Information System (INIS)

    2010-01-01

    The potential of a malicious act involving nuclear or other radioactive material is a continuing worldwide threat. Available data indicate circumstances in which nuclear and other radioactive material are vulnerable to theft, are uncontrolled, or are in unauthorized circulation. States must establish sustainable security measures to prevent such acts and to protect society from nuclear terrorism. Appropriate training and education at all levels and in all relevant organizations and facilities can play a major role in this process. There is increased interest in nuclear applications. Many States have expressed interest in expanding or introducing nuclear power in their country as a result of their own assessment of their energy supply needs, because of climate change, and development requirements. The projected increase in the demand for nuclear energy will increase the number of nuclear reactors worldwide and, consequently, the amount of nuclear material in use. Possible malicious acts involving nuclear or other radioactive material are a real threat. These developments are mirrored by an increase in the use of nuclear techniques in non-power applications. As a result, the need for experts in the area of nuclear security has become of great importance, and both universities and students have shown an increasing interest in nuclear security specialities. In September 2005, the Board of Governors approved a Nuclear Security Plan covering the period 2006-2009. This emphasized, inter alia, the importance of human resource development to assist States in building capacity to establish and maintain appropriate nuclear security to prevent, detect and respond to malicious acts involving nuclear and other radioactive material. The Nuclear Security Plan envisages the development of guidance for an educational programme in nuclear security that could be used by all States. In pursuit of this goal, this publication has been developed to provide advice and assistance to

  6. Fault detection of sensors in nuclear reactors using self-organizing maps

    International Nuclear Information System (INIS)

    Barbosa, Paulo Roberto; Tiago, Graziela Marchi; Bueno, Elaine Inacio; Pereira, Iraci Martinez

    2011-01-01

    In this work a Fault Detection System was developed based on the self-organizing maps methodology. This method was applied to the IEA-R1 research reactor at IPEN using a database generated by a theoretical model of the reactor. The IEA-R1 research reactor is a pool type reactor of 5 MW, cooled and moderated by light water, and uses graphite and beryllium as reflector. The theoretical model was developed using the Matlab Guide toolbox. The equations are based in the IEA-R1 mass and energy inventory balance and physical as well as operational aspects are taken into consideration. In order to test the model ability for fault detection, faults were artificially produced. As the value of the maximum calibration error for special thermocouples is +- 0.5 deg C, it had been inserted faults in the sensor signals with the purpose to produce the database considered in this work. The results show a high percentage of correct classification, encouraging the use of the technique for this type of industrial application. (author)

  7. Chromatin structure and replication origins: determinants of chromosome replication and nuclear organization.

    Science.gov (United States)

    Smith, Owen K; Aladjem, Mirit I

    2014-10-09

    The DNA replication program is, in part, determined by the epigenetic landscape that governs local chromosome architecture and directs chromosome duplication. Replication must coordinate with other biochemical processes occurring concomitantly on chromatin, such as transcription and remodeling, to insure accurate duplication of both genetic and epigenetic features and to preserve genomic stability. The importance of genome architecture and chromatin looping in coordinating cellular processes on chromatin is illustrated by two recent sets of discoveries. First, chromatin-associated proteins that are not part of the core replication machinery were shown to affect the timing of DNA replication. These chromatin-associated proteins could be working in concert, or perhaps in competition, with the transcriptional machinery and with chromatin modifiers to determine the spatial and temporal organization of replication initiation events. Second, epigenetic interactions are mediated by DNA sequences that determine chromosomal replication. In this review, we summarize recent findings and current models linking spatial and temporal regulation of the replication program with epigenetic signaling. We discuss these issues in the context of the genome's three-dimensional structure with an emphasis on events occurring during the initiation of DNA replication. Published by Elsevier Ltd.

  8. Fault detection of sensors in nuclear reactors using self-organizing maps

    Energy Technology Data Exchange (ETDEWEB)

    Barbosa, Paulo Roberto; Tiago, Graziela Marchi [Instituto Federal de Educacao, Ciencia e Tecnologia de Sao Paulo (IFSP), Sao Paulo, SP (Brazil); Bueno, Elaine Inacio [Instituto Federal de Educacao, Ciencia e Tecnologia de Sao Paulo (IFSP), Guarulhos, SP (Brazil); Pereira, Iraci Martinez, E-mail: martinez@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    In this work a Fault Detection System was developed based on the self-organizing maps methodology. This method was applied to the IEA-R1 research reactor at IPEN using a database generated by a theoretical model of the reactor. The IEA-R1 research reactor is a pool type reactor of 5 MW, cooled and moderated by light water, and uses graphite and beryllium as reflector. The theoretical model was developed using the Matlab Guide toolbox. The equations are based in the IEA-R1 mass and energy inventory balance and physical as well as operational aspects are taken into consideration. In order to test the model ability for fault detection, faults were artificially produced. As the value of the maximum calibration error for special thermocouples is +- 0.5 deg C, it had been inserted faults in the sensor signals with the purpose to produce the database considered in this work. The results show a high percentage of correct classification, encouraging the use of the technique for this type of industrial application. (author)

  9. Analysis of minor incidents in the operation of nuclear power plants: a case study on the use of procedures in organizations dealing with hazardous technologies

    International Nuclear Information System (INIS)

    Carvalho, Paulo Victor Rodrigues de; Vidal, Mario Cesar Rodriguea; Carvalho, Eduardo Ferro de

    2005-01-01

    Organizations that work with hazardous materials, such as nuclear power plants, offshore installations, and chemical and petrochemical plants, have risk management systems involving accident control and mitigation to ensure the safety of their facilities. These systems are based on physical devices, such as protective barriers, equipment and systems aimed at preventing the occurrence and propagation of accidents, and on human aspects such as regulations and procedures. This paper analyzes the use of a variety of procedures by nuclear power plant control room operators. The methodology consisted of analyzing the work of control room operators during the normal operations, shutdown, and startup of a nuclear power plant, and in full scale simulator training. This survey revealed that routine noncompliance to procedures was considered normal according to the operating rationale, which is based on technical, organizational and cultural factors. These findings indicate that the competencies nuclear power plant operators must possess far exceed proper technical training and the ability to follow written instructions. (author)

  10. Experimental ratio between the 'real' dose per organ and the calculated dose determined by means of the Embalse nuclear power plant's personal dosimeter

    International Nuclear Information System (INIS)

    Thomasz, E.; Salas, C.A.

    1987-01-01

    The specific purpose of the study was to determine the experimental ratio between the reading of dosimeters used by the personnel of the Embalse nuclear power plant and the 'real' dose absorbed by the worker in different organs. An anthropomorphic phantom ALDERSON internal and externally loaded with approximately 150 TLD crystals was used. This phantom was placed in five enclosures that were usually occupied by workers of the Embalse nuclear power plant. In this way, the average dose per organ and the effective equivalent dosis in each enclosure could be calculated and compared with the personal dosimeters placed over the thorax and the conversion factor rem/rem for each enclosure was determined. The average factor resulting from the five considered enclosures was 0.73 rem/rem. This means that the personal dosimeters over value the real dosis absorbed by the personnel of the Embalse nuclear power plant in approximately 37%. (Author)

  11. The Science of Nuclear Safety and Security. IAEA Backs the Work of Technical and Scientific Support Organizations in Safety and Security

    International Nuclear Information System (INIS)

    Verlini, Giovanni

    2011-01-01

    Expertise in physical protection and accounting of nuclear and other radioactive material in use, storage and transport, and the associated facilities, as well as experience in the maintenance of systems, equipment and associated software used for effective border monitoring and for radiological threat assessment, are the fundaments of safety and security. This knowledge is developed through technical and scientific support organizations (TSOs), neutral and official organizations that provide the basis for decisions and activities regarding nuclear and radiation safety. The quality of the technical and scientific expertise provided by TSOs to the nuclear industry and their contribution to effective regulatory systems are of fundamental importance. For many years, the IAEA has been supporting the work of TSOs, by helping the TSOs promote their technical competence, transparency and observance of ethical principles.

  12. Function of nuclear membrane proteins in shaping the nuclear envelope integrity during closed mitosis.

    Science.gov (United States)

    Yang, Hui-Ju; Iwamoto, Masaaki; Hiraoka, Yasushi; Haraguchi, Tokuko

    2017-06-01

    The nuclear envelope (NE) not only protects the genome from being directly accessed by detrimental agents but also regulates genome organization. Breaches in NE integrity threaten genome stability and impede cellular function. Nonetheless, the NE constantly remodels, and NE integrity is endangered in dividing or differentiating cells. Specifically, in unicellular eukaryotes undergoing closed mitosis, the NE expands instead of breaking down during chromosome segregation. The newly assembling nuclear pore complexes (NPCs) penetrate the existing NE in interphase. A peculiar example of NE remodelling during nuclear differentiation in Tetrahymena involves formation of the redundant NE and clustered NPCs. Even under these conditions, the NE remains intact. Many recent studies on unicellular organisms have revealed that nuclear membrane proteins, such as LEM-domain proteins, play a role in maintaining NE integrity. This review summarizes and discusses how nuclear membrane proteins participate in NE integrity. © The Authors 2017. Published by Oxford University Press on behalf of the Japanese Biochemical Society. All rights reserved.

  13. Nuclear Safety through International Cooperation

    International Nuclear Information System (INIS)

    Flory, Denis

    2013-01-01

    The Fukushima Daiichi nuclear accident was the worst at a nuclear facility since the Chernobyl accident in 1986. It caused deep public anxiety and damaged confidence in nuclear power. Following this accident, strengthening nuclear safety standards and emergency response has become an imperative at the global level. The IAEA is leading in developing a global approach, and the IAEA Action Plan on Nuclear Safety is providing a comprehensive framework and acting as a significant driving force to identify lessons learned and to implement safety improvements. Strengthening nuclear safety is addressed through a number of measures proposed in the Action Plan including 12 main actions focusing on safety assessments in the light of the accident. Significant progress has been made in assessing safety vulnerabilities of nuclear power plants, strengthening the IAEA's peer review services, improvements in emergency preparedness and response capabilities, strengthening and maintaining capacity building, as well as widening the scope and enhancing communication and information sharing with Member States, international organizations and the public. Progress has also been made in reviewing the IAEA's safety standards, which continue to be widely applied by regulators, operators and the nuclear industry in general, with increased attention and focus on accident prevention, in particular severe accidents, and emergency preparedness and response.

  14. Themes in nuclear law

    International Nuclear Information System (INIS)

    2003-01-01

    The nuclear law was analyzed during a workshop. The main aspects were: the law of population to access to information on nuclear energy and the relationship between the Regulator Organism and the nuclear power plants managers

  15. Organics.

    Science.gov (United States)

    Chian, Edward S. K.; DeWalle, Foppe B.

    1978-01-01

    Presents water analysis literature for 1978. This review is concerned with organics, and it covers: (1) detergents and surfactants; (2) aliphatic and aromatic hydrocarbons; (3) pesticides and chlorinated hydrocarbons; and (4) naturally occurring organics. A list of 208 references is also presented. (HM)

  16. Organizers.

    Science.gov (United States)

    Callison, Daniel

    2000-01-01

    Focuses on "organizers," tools or techniques that provide identification and classification along with possible relationships or connections among ideas, concepts, and issues. Discusses David Ausubel's research and ideas concerning advance organizers; the implications of Ausubel's theory to curriculum and teaching; "webbing," a…

  17. Plasma Nuclear and Mitochondrial DNA Levels, and Markers of Inflammation, Shock, and Organ Damage in Patients with Septic Shock.

    Science.gov (United States)

    Timmermans, Kim; Kox, Matthijs; Scheffer, Gert Jan; Pickkers, Peter

    2016-06-01

    Plasma levels of the danger-associated molecular patterns (DAMPs) nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) have been shown to be related to sepsis mortality. However, the intermediate factors and/or mechanisms contributing to this relation are largely unknown. Our aim was to determine whether plasma levels of nDNA and mtDNA are related to the markers of inflammation, severity of shock, and organ damage in septic shock patients. Moreover, we investigated the relationship between plasma levels of nDNA/mtDNA and inflammatory cytokines during experimental human endotoxemia, a model of systemic inflammation in humans in vivo mimicking some of the hallmarks of early sepsis. Blood was sampled from the onset of septic shock until day 28 in 121 septic shock patients and from 1 h before endotoxin administration until 8 h afterward in 12 healthy volunteers. Plasma concentrations of five cytokines and circulating levels of nDNA and mtDNA were measured, and correlations with shock-related parameters and markers of organ damage were investigated. In septic shock patients plasma cytokine concentrations, as well as nDNA and mtDNA levels, were increased at the onset of septic shock and remained elevated. During the first 5 days of septic shock, nDNA levels consistently correlated with plasma cytokine concentrations as well as with the shock-related parameter norepinephrine infusion rate and markers of organ damage (total bilirubin and creatinine). Experimental human endotoxemia also resulted in increased levels of plasma nDNA and mtDNA, but to a lesser extent than in septic shock patients. Furthermore, nDNA levels correlated with pro-inflammatory cytokines during endotoxemia. Our findings indicate a relationship between plasma nDNA levels and the inflammatory response. Furthermore, nDNA levels are associated with markers of shock and organ damage in septic shock patients. Nevertheless, the correlations found are relatively weak and it remains to be determined whether n

  18. Europe's nuclear dominos

    International Nuclear Information System (INIS)

    Sharp, J.

    1993-01-01

    As long as the United States continues to play a leading role in NATO, the incentive for European powers to acquire independent nuclear weapons is virtually zero. Most European power, however, have relatively sophisticated nuclear establishments and could easily manufacture nuclear explosives if they judged that their security required an independent capability. They might judge so if the United States pulls out of Europe and out of NATO. It is the opinion of the author that if the United States withdraws, and if France and Britain insist on maintaining their current status as independent nuclear weapons powers, they will encourage proliferation by example. The likelihood of different countries deciding to manufacture nuclear weapons under these cicumstances is evaluated. The future of NATO is assessed. The conclusions of and future structure of the Conference on Cooperation and Security in Europe (CSCE) is discussed. The impact of United Nations involvement in preventing proliferation is evaluated. Recommendations are proposed for the utilization of existing organizations to deter proliferation in Europe

  19. Nuclear lipid droplets: a novel nuclear domain.

    Science.gov (United States)

    Layerenza, J P; González, P; García de Bravo, M M; Polo, M P; Sisti, M S; Ves-Losada, A

    2013-02-01

    We investigated nuclear neutral-lipid (NL) composition and organization, as NL may represent an alternative source for providing fatty acids and cholesterol (C) to membranes, signaling paths, and transcription factors in the nucleus. We show here that nuclear NL were organized into nonpolar domains in the form of nuclear-lipid droplets (nLD). By fluorescent confocal microscopy, representative nLD were observed in situ within the nuclei of rat hepatocytes in vivo and HepG2 cells, maintained under standard conditions in culture, and within nuclei isolated from rat liver. nLD were resistant to Triton X-100 and became stained with Sudan Red, OsO4, and BODIPY493/503. nLD and control cytosolic-lipid droplets (cLD) were isolated from rat-liver nuclei and from homogenates, respectively, by sucrose-gradient sedimentation. Lipids were extracted, separated by thin-layer chromatography, and quantified. nLD were composed of 37% lipids and 63% proteins. The nLD lipid composition was as follows: 19% triacylglycerols (TAG), 39% cholesteryl esters, 27% C, and 15% polar lipids; whereas the cLD composition contained different proportions of these same lipid classes, in particular 91% TAG. The TAG fatty acids from both lipid droplets were enriched in oleic, linoleic, and palmitic acids. The TAG from the nLD corresponded to a small pool, whereas the TAG from the cLD constituted the main cellular pool (at about 100% yield from the total homogenate). In conclusion, nLD are a domain within the nucleus where NL are stored and organized and may be involved in nuclear lipid homeostasis. Copyright © 2012 Elsevier B.V. All rights reserved.

  20. Identification of organization values according to the perception of the employees of the Energetic and Nuclear Research Institute - IPEN

    International Nuclear Information System (INIS)

    Pupak, Marcia Orrico; Roman, Edson; Perrota, Jose Augusto; Feher, Ana Claudia M.; Magalhaes, Adriana B.V.B.; Massi, Maria Julia Gili; Rogero, Jose Roberto; Maximiano, Antonio Cesar Amaru

    2002-01-01

    The purpose of this research was to identify the organizational values, according to the perception of employees of the Energetic and Nuclear Research Institute - IPEN. The instrument used in this research was the 'Organization Values Questionnaire'. This survey contains a list with 38 values, each followed by a parenthetical explanation that clarifies its meaning. Respondents rated each value on a 6-point scale from, less important (0) to very important (6), in response to the question: How important is each values for the organizational life? This evaluation should be done in two levels of perception: REAL plan, and IDEAL plan. The population investigated was constituent by 1000 employees. The total of 553, i.e. 55.3%, questionnaires were turned back. As result, it was identified on REAL plan, values related to coefficient as EFFICIENCY, EFFICACY and MANAGEMENT. On IDEAL plan, they were related to EMPLOYEE VALORIZATION and INOVATION coefficient. As consequence, the institutional commitment is to form working groups, inside the Strategic Planning Revision, in order to elaborate the Core Values, based on the values identified on this research. (author)

  1. Organization and methodology applied to the control of commissioning tests to guarantee safe operation of nuclear units

    International Nuclear Information System (INIS)

    Clausner, J.P.; Jorel, M.

    1990-12-01

    This paper describes the activities of the Safety Analysis Department (DAS), which provides technical support for the French safety authorities in the specific context of analysis and control of startup test programme quality at each of the different stages of the programme. These activities combine to ensure that the objective of the startup tests is reached, in particular that the functions of each safety-related system are guaranteed in all operating configurations, that the performance levels of all components in the system comply with design criteria and that defects revealed during previous tests have been dealt with correctly. The special case of French nuclear facilities, linked to unit standardization, has made it possible to acquire a large amount of experience with the startup of the 900 MWe units and has illustrated the importance of defining a startup test programme. In 1981, a working group, comprising operating organization and safety authority representatives, studied the lessons which had to be learned from 900 MWe unit startup and the improvements which could be made and taken into account in the 1300 MWe unit startup programme. To illustrate the approach adopted by the DAS, we go on to describe the lessons learned from startup of the first 1300 MWe (P4) units

  2. Organizations

    DEFF Research Database (Denmark)

    Hatch, Mary Jo

    Most of us recognize that organizations are everywhere. You meet them on every street corner in the form of families and shops, study in them, work for them, buy from them, pay taxes to them. But have you given much thought to where they came from, what they are today, and what they might become...... and considers many more. Mary Jo Hatch introduces the concept of organizations by presenting definitions and ideas drawn from the a variety of subject areas including the physical sciences, economics, sociology, psychology, anthropology, literature, and the visual and performing arts. Drawing on examples from...... prehistory and everyday life, from the animal kingdom as well as from business, government, and other formal organizations, Hatch provides a lively and thought provoking introduction to the process of organization....

  3. Organizations

    DEFF Research Database (Denmark)

    Hatch, Mary Jo

    and considers many more. Mary Jo Hatch introduces the concept of organizations by presenting definitions and ideas drawn from the a variety of subject areas including the physical sciences, economics, sociology, psychology, anthropology, literature, and the visual and performing arts. Drawing on examples from......Most of us recognize that organizations are everywhere. You meet them on every street corner in the form of families and shops, study in them, work for them, buy from them, pay taxes to them. But have you given much thought to where they came from, what they are today, and what they might become...... prehistory and everyday life, from the animal kingdom as well as from business, government, and other formal organizations, Hatch provides a lively and thought provoking introduction to the process of organization....

  4. Monte-Carlo based assessment of MAGIC, MAGICAUG, PAGATUG and PAGATAUG polymer gel dosimeters for ovaries and uterus organ dosimetry in brachytherapy, nuclear medicine and Tele-therapy.

    Science.gov (United States)

    Adinehvand, Karim; Rahatabad, Fereidoun Nowshiravan

    2018-06-01

    Calculation of 3D dose distribution during radiotherapy and nuclear medicine helps us for better treatment of sensitive organs such as ovaries and uterus. In this research, we investigate two groups of normoxic dosimeters based on meta-acrylic acid (MAGIC and MAGICAUG) and polyacrylamide (PAGATUG and PAGATAUG) for brachytherapy, nuclear medicine and Tele-therapy in their sensitive and critical role as organ dosimeters. These polymer gel dosimeters are compared with soft tissue while irradiated by different energy photons in therapeutic applications. This comparison has been simulated by Monte-Carlo based MCNPX code. ORNL phantom-Female has been used to model the critical organs of kidneys, ovaries and uterus. Right kidney is proposed to be the source of irradiation and another two organs are exposed to this irradiation. Effective atomic numbers of soft tissue, MAGIC, MAGICAUG, PAGATUG and PAGATAUG are 6.86, 7.07, 6.95, 7.28, and 7.07 respectively. Results show the polymer gel dosimeters are comparable to soft tissue for using in nuclear medicine and Tele-therapy. Differences between gel dosimeters and soft tissue are defined as the dose responses. This difference is less than 4.1%, 22.6% and 71.9% for Tele-therapy, nuclear medicine and brachytherapy respectively. The results approved that gel dosimeters are the best choice for ovaries and uterus in nuclear medicine and Tele-therapy respectively. Due to the slight difference between the effective atomic numbers of these polymer gel dosimeters and soft tissue, these polymer gels are not suitable for brachytherapy since the dependence of photon interaction to atomic number, for low energy brachytherapy, had been so effective. Also this dependence to atomic number, decrease for photoelectric and increase for Compton. Therefore polymer gel dosimeters are not a good alternative to soft tissue replacement in brachytherapy. Copyright © 2018 Elsevier B.V. All rights reserved.

  5. A lead user of instruments in science: John D. Roberts and the adaptation of nuclear magnetic resonance to organic chemistry, 1955-1975.

    Science.gov (United States)

    Reinhardt, Carsten

    2006-06-01

    During the 1960s organic chemistry underwent a spectacular transformation as a result of the introduction of high-tech instruments. In this process, nuclear magnetic resonance (NMR) became an important analytical technique in organic chemistry. The theme of this essay is the relationship of Varian Associates of Palo Alto, California, the major manufacturer of NMR spectrometers up to the 1970s, with one early and crucial user, the organic chemist John D. Roberts, who was based at the California Institute of Technology in Pasadena. Roberts's research and teaching contributed to the fast and smooth acceptance of NMR in organic chemistry. He embraced the role of mediator between the instrument manufacturer, which had expertise mainly in physics and electrical engineering, and the customers, who were mostly organic chemists. This essay focuses on the tactics used by Roberts and James N. Shoolery at Varian Associates to implement novel types of instrumentation and on the modes of cooperation between instrument manufacturer and academic scientist.

  6. Nuclear reaction

    CERN Multimedia

    Penwarden, C

    2001-01-01

    At the European Research Organization for Nuclear Research, Nobel laureates delve into the mysteries of particle physics. But when they invited artists from across the continent to visit their site in Geneva, they wanted a new kind of experiment.

  7. Human Resource Development in a Newcomer Country: MNPC’s Experience as a Dedicated Nuclear Energy Programme Implementing Organization (NEPIO)

    International Nuclear Information System (INIS)

    Mohd Zamzam Jaafar

    2014-01-01

    Concluding remarks: The establishment of MNPC as a fully dedicated NEPIO facilitates a focused drive towards implementation of a nuclear energy development program for Malaysia. Now, 3 years after its establishment, MNPC will continue to spearhead and coordinate collaborative national efforts towards enabling a well-informed Government decision on the option of using nuclear power post-2020. Nuclear Power Infrastructure Development Plan (NPIDP) is being prepared by Consultant engaged by MNPC and expected to be completed in Dec 2014 Professionals including stakeholders involved with nuclear power planning and programmeimplementation, could also serve as a pool of experts & personnel to staff relevant future organisations needed for NPP development

  8. Education and Training, and Knowledge Networks for Capacity-Building in Nuclear Security

    International Nuclear Information System (INIS)

    Mrabit, Khammar

    2014-01-01

    Conclusions: • Capacity Building (CB) is critical for States to establish and maintain effective and sustainable nuclear security regime. • IAEA is a worldwide platform promoting international cooperation for CB in nuclear security involving more than 160 countries and over 20 Organizations and Initiatives. • IAEA Division of Nuclear Security is ready to continue supporting States in developing their CB through: – Comprehensive Training Programme: more than 80 training events annually – International Nuclear Security Training and Support Centre Network (NSSC) – Comprehensive Education Programme – International Nuclear Security Network (INSEN)

  9. Nuclear industry and the management of accident risk in Europe: from the internalisation default to the coverage organization

    International Nuclear Information System (INIS)

    Fiore, K.

    2007-12-01

    The production of nuclear energy creates environmental and sanitary risks among which the risk of nuclear accident. There is a twofold dimension in the management of such a risk: a preventive dimension and a compensatory one. Given its catastrophic and unpredictable character, the nuclear risk has always been managed in a specific way. In Europe, its management is unsatisfactory. The civil liability regime is beneficial to the nuclear industry as it leads to a lack of internalisation and thus to a limited coverage of potential damages. The financial cap of the nuclear operator's civil liability reduces his incentives for the prevention of accidents. By narrowing its liability, it also limits the burden tied to the coverage of the full potential damages. The organisation of the nuclear risk coverage was heavily conditioned by the civil liability regime and the financial cap it creates. Such an organisation is inefficient. The nuclear insurance market's financial capacity is not enough to compensate for all the potential victims of a major nuclear accident. Moreover, the functioning of this market is quite costly for the nuclear operator. While new electronuclear projects are being launched in Europe, the management of nuclear risks must be questioned in order to find better solutions to the necessity of internalising, preventing and compensating. Nuclear operators should be responsible for all the damages caused through an unlimited liability rule. The coverage of potential damages could also be improved by setting up a risk-sharing agreement at the European scale between operators. (author)

  10. Soil organic matter composition from correlated thermal analysis and nuclear magnetic resonance data in Australian national inventory of agricultural soils

    Science.gov (United States)

    Moore, T. S.; Sanderman, J.; Baldock, J.; Plante, A. F.

    2016-12-01

    National-scale inventories typically include soil organic carbon (SOC) content, but not chemical composition or biogeochemical stability. Australia's Soil Carbon Research Programme (SCaRP) represents a national inventory of SOC content and composition in agricultural systems. The program used physical fractionation followed by 13C nuclear magnetic resonance (NMR) spectroscopy. While these techniques are highly effective, they are typically too expensive and time consuming for use in large-scale SOC monitoring. We seek to understand if analytical thermal analysis is a viable alternative. Coupled differential scanning calorimetry (DSC) and evolved gas analysis (CO2- and H2O-EGA) yields valuable data on SOC composition and stability via ramped combustion. The technique requires little training to use, and does not require fractionation or other sample pre-treatment. We analyzed 300 agricultural samples collected by SCaRP, divided into four fractions: whole soil, coarse particulates (POM), untreated mineral associated (HUM), and hydrofluoric acid (HF)-treated HUM. All samples were analyzed by DSC-EGA, but only the POM and HF-HUM fractions were analyzed by NMR. Multivariate statistical analyses were used to explore natural clustering in SOC composition and stability based on DSC-EGA data. A partial least-squares regression (PLSR) model was used to explore correlations among the NMR and DSC-EGA data. Correlations demonstrated regions of combustion attributable to specific functional groups, which may relate to SOC stability. We are increasingly challenged with developing an efficient technique to assess SOC composition and stability at large spatial and temporal scales. Correlations between NMR and DSC-EGA may demonstrate the viability of using thermal analysis in lieu of more demanding methods in future large-scale surveys, and may provide data that goes beyond chemical composition to better approach quantification of biogeochemical stability.

  11. Pursuit of nuclear science and technology education

    International Nuclear Information System (INIS)

    Rangacharyulu, C.

    2009-01-01

    While it is quite encouraging to note that there is a nuclear renaissance underway around the world, there is a growing concern that the knowledge-base of nuclear technologies will be lost. Several international organizations are making concerted efforts to avert this situation by establishing collaborative workshops etc. In Western Canada, our challenges and opportunities are many-fold. As a uranium mining region, we can engage our economy in the full life-cycle of the nuclear energy industry. It is also important that we maintain and augment nuclear technologies. We need to develop the infrastructure to jump-start the education and training of the youth. We are taking a multi-prong approach to this end. We are initiating specializations in undergraduate programs which emphasize nuclear radiation physics and technology. We are collaborating with Canadian organizations such as University Network of Excellence in Nuclear Engineering (UNENE) and University of Ontario Institute of Technology (UOIT). We are organizing collaborations with our colleagues at foreign institutions in Europe and Asia to provide an international component. We are also working with local industry and health organizations to provide a wide-range of learning opportunities to students by engaging them in research projects of immediate interest to professionals. My presentation will focus on these developments and we will also seek thoughts and suggestions for future collaborations.

  12. Nuclear Energy Agency

    International Nuclear Information System (INIS)

    2011-01-01

    out research or scientific inter comparison exercises on a cost sharing basis; - The NEA, as part of a larger multi-disciplinary organization, is uniquely placed to address nuclear energy in the context of broader cross-cutting issues such as sustainable development. Through international cooperation, NEA assists its member states to maintain and further develop the scientific, technological and legal bases required for a safe, environmentally friendly and economical use of nuclear energy for peaceful purposes. The NEA also provides authoritative assessments and forges common understandings on key issues, as input to government decisions on nuclear energy policy and to broader OECD policy analyses in areas such as energy and sustainable development. It is a non-partisan, unbiased source of information, data and analyses, drawing on one of the best international networks of technical experts. In nuclear technology related tasks, NEA works in close collaboration with the IAEA and other international organization in this field. The Commission of the European Communities also takes part in the work of the NEA. The International School of Nuclear Law (ISNL) was established in 2001 by the University of Montpellier 1 and the NEA. The ISNL is supported by the International Nuclear Law Association (INLA) and the IAEA. The ISNL aims to provide a high quality course of education on the various aspects of this discipline. It is open to both law students pursuing their studies at doctoral or masters level who wish to follow an introductory course on nuclear law and familiarize themselves with career opportunities open to them in this field. It is also open to young legal professionals who are already active in the nuclear sector and who wish to develop their knowledge. Independent of its teaching role, the School serves as a forum for students to meet recognized specialists in nuclear law in a studious yet convivial atmosphere. NEA also cooperates in organization of WNU Summer

  13. Nuclear electronics

    International Nuclear Information System (INIS)

    Lucero B, E.

    1989-01-01

    The rapid technical development of Colombia over the past years, resulted among others, a considerable increase in the number of measuring instrumentation and testing laboratories, scientific research and metrology centers, in industry, agriculture, public health, education on the nuclear field, etc. IAN is a well organized institution with qualified management, trained staff and reasonably equipped laboratories to carry out tasks as: Metrology, standardization, quality control and maintenance and repair of nuclear instruments. The government of Colombia has adopted a policy to establish and operate through the country maintenance and repair facilities for nuclear instrumentation. This policy is reflected in the organization of electronic laboratories in Bogota-IAN

  14. Status of the organs of the digestive system in employees of the Chernobyl nuclear power plant engaged in recovery work after the accident

    International Nuclear Information System (INIS)

    Yaimenko, L.; Moroz, G.Z.; Sobchuk, Y.A.

    1995-01-01

    This work deals with the status of the digestive system in employees of the Chernobyl nuclear power plant engaged in recovery work after the accident. Morphological and functional changes suffered by the digestive organs on exposure to ionizing radiation in doses leading to the development of acute radiation sickness are described. The effect of small doses ionizing radiation on the human body is indicated too. (O.L.). 15 refs., 1 tab

  15. Radioactive waste isolation in salt: peer review of the Office of Nuclear Waste Isolation's report on the Organic Geochemistry of Deep Groundwaters from the Palo Duro Basin, Texas

    International Nuclear Information System (INIS)

    Fenster, D.F.; Brookins, D.G.; Harrison, W.; Seitz, M.G.; Lerman, A.; Stamoudis, V.C.

    1984-08-01

    This report summarizes Argonne's review of the Office of Nuclear Waste Isolation's (ONWI's) final report entitled The Organic Geochemistry of Deep Ground Waters from the Palo Duro Basin, Texas, dated September 1983. Recommendations are made for improving the ONWI report. The main recommendation is to make the text consistent with the title and with the objective of the project as stated in the introduction. Three alternatives are suggested to accomplish this

  16. Quality assurance for nuclear power plants. Proceedings of an international symposium organized by the IAEA and held in Paris, 11-15 May 1981

    International Nuclear Information System (INIS)

    1982-01-01

    The International Symposium on Quality Assurance for Nuclear Power Plants, organized by the International Atomic Energy Agency, was held in Paris from 11 to 15 May 1981. The main objectives of the symposium were the following: (1) To review the present requirements and practices in implementing quality assurance (QA) in nuclear power projects in Member States; (2) To identify the existing similarities and differences and to highlight those aspects of QA in Member States which are controversial and in need of harmonization; (3) To assess the practical use of the established requirements and recommendations of the IAEA Code of Practice on Quality Assurance for Safety in Nuclear Power Plants and the relevant Safety Guides. Because of the interdisciplinary nature of QA and the rather broad scope of its activities, only seven topics of QA were selected for review and discussion. They included, besides a general comparison of QA requirements and practices in IAEA Member States, methodologies for the selection of appropriate QA programme levels for specific items and services; the role of independent inspection in verification activities; economic aspects of QA; manpower requirements for QA in nuclear power projects; training, qualification and certification of QA personnel; and specific aspects of the implementation of QA in countries embarking on nuclear power projects. Each of these topics was treated in a separate session. These Proceedings include the full text of all invited papers and of a large part of the contributed papers. The contributed papers that are not published in full are represented by abstracts in the session summaries. The summaries of the sessions as prepared by the working groups appear at the end of the appropriate sessions. The holding of an international symposium on quality assurance appeared well timed. The importance of QA in the nuclear industry is constantly growing with the increasing requirements for safety and availability of nuclear

  17. Spain's nuclear components industry

    International Nuclear Information System (INIS)

    Kaibel, E.

    1985-01-01

    Spanish industrial participation in supply of components for nuclear power plants has grown steadily over the last fifteen years. The share of Spanish companies in work for the five second generation nuclear power plants increased to 50% of total capital investments. The necessity to maintain Spanish technology and production in the nuclear field is emphasized

  18. State and regional systems of accounting for and control of nuclear materials cooperation between international, regional and states safeguards organizations: An evolving issue

    International Nuclear Information System (INIS)

    Fernández Moreno, Sonia

    2011-01-01

    Cooperation between the IAEA, States and regional organizations is increasingly important to ensure effective accountancy and control of nuclear material in peaceful uses. The IAEA, SAGSI2 and institutions such INMM3 and ESARDA4 have recognized the relevance and the evolving role that SSAC5 and regional organizations play to this aim. In this context, it is important to take steps to ensure the effectiveness of the system and the optimal level of relationship between these organizations so as to maximize the benefits for each party, particularly in those cases where well developed systems exist. Moreover, expansion of nuclear energy requires concerted efforts towards building competence in safeguards in all relevant States. This is also important with respect to other aspects of nonproliferation. In this scenario there is agreement on the need to have effective state organizations that fulfill international safeguards and other security obligations. However, the roles and duties of SSAC and the possible scope of cooperation between the IAEA and SSAC are still under evolution. This paper discusses possible ways and means to build competence in safeguards and how the international community could be more proactive in establishing a framework including the various dimensions of the cooperation in safeguards and other security matters between all parties concerned. The establishment of a forum and a network of interested parties under the auspice of interested organizations could be one mechanism to exchange best practices and experiences. (authors)

  19. Higher order nuclear organization in growth arrest of humanmammary epithelial cells: A novel role for telomere-associated proteinTIN2

    Energy Technology Data Exchange (ETDEWEB)

    Kaminker, Patrick; Plachot, Cedric; Kim, Sahn-Ho; Chung, Peter; Crippen, Danielle; Petersen, Ole W.; Bissell, Mina J.; Campisi, Judith; Lelievre, Sophie A.

    2004-12-15

    Nuclear organization, such as the formation of specific nuclear subdomains, is generally thought to be involved in the control of cellular phenotype; however, there are relatively few specific examples of how mammalian nuclei organize during radical changes in phenotype, such as those which occur during differentiation and growth arrest. Using human mammary epithelial cells (HMECs) in which growth arrest is essential for morphological differentiation, we show that the arrest of cell proliferation is accompanied by a reorganization of the telomere-associated protein, TIN2, into one to three large nuclear subdomains. The large TIN2 domains do not contain telomeres and occur concomitant with the continued presence of TIN2 at telomeres. The TIN2 domains were sensitive to DNAse, but not RNAse, occurred frequently, but not exclusively near nucleoli, and overlapped often with dense domains containing heterochromatin protein l{gamma}. Expression of truncated forms of TIN2 simultaneously prevented the formation of TIN2 domains and relaxed the stringent morphogenesis-induced growth arrest in HMECs. Our findings reveal a novel extra-telomeric organization of TIN2 associated with the control of cell proliferation and identify TIN2 as an important regulator of mammary epithelial differentiation.

  20. Maintaining oral health after stroke.

    Science.gov (United States)

    Dickinson, Hazel

    Oral care is essential to maintain oral health and prevent complications such as tooth loss, gingivitis and periodontitis. Poor oral hygiene in dependent, hospitalised patients could lead to serious complications such as chest infection, pneumonia, poor nutritional intake and increased length of hospital stay. Patients who have had a stroke may have physical and cognitive problems that make them dependent on others for their personal care, including oral care. It is essential that nurses and carers understand why maintaining oral hygiene is important following stroke and the consequences of poor oral care.

  1. The Nuclear Safety Council in the National System of Nuclear and Radiological Emergencies. Functions, organization and new international trends; El Consejo de Seguridad Nuclear en el Sistema Nacional de Emergencias Nucleares y Radiológicas. Funciones, organización y nuevas tendencias internacionales

    Energy Technology Data Exchange (ETDEWEB)

    Mozas García, A.; Martín Calvarro, J.M.; García Cadierno, J.P.; Calvín Cuartero, M.

    2015-07-01

    This article describes the role of the Spanish Nuclear Safety Council (CSN) in the coordination of nuclear and radiológicas emergencies, and how they engage with the National Nuclear and Radiological Emergency System. To accomplish its functions, the CSN, has set up the Emergency Response Organization (ORE), which structure, functions and procedures are also described in this work. Finally, the new international trends that are being developed on emergency preparedness and response as a consequence of the lessons learned from recent disasters are reported. [Spanish] Este artículo revisa las funciones que el Consejo de Seguridad tiene en la coordinación de las emergencias nucleares y radiológicas, y cómo se engranan éstas en el Sistema Nacional de Emergencias. A partir de las funciones que tiene encomendadas se describe la organización del CSN en emergencias y la estructura de los apoyos con los que cuenta para cumplir con aquéllas. Por último, se revisan las tendencias que, a nivel internacional, se están desarrollando para incorporar a la preparación de la respuesta a emergencias las lecciones aprendidas de las últimas catástrofes ocurridas.

  2. Security with nuclear weapons

    International Nuclear Information System (INIS)

    Karp, R.C.

    1991-01-01

    Recent improvements in East-West relations and the process of dramatic political change in Europe may result in unprecedented opportunities to reduce the global arsenal of nuclear weapons. Despite these welcome developments, the prospects for effectively controlling the spread of nuclear capability in the Third World have remained much less encouraging. The possibility of large reductions in nuclear weapons poses fundamental questions about their purpose. Why have some states chosen to acquire nuclear weapons? How and why have these decisions been maintained over time? Why have some states elected to approach, but not cross, the nuclear threshold? This book examines the commonalities and differences in political approaches to nuclear weapons both within and between three groups of states: nuclear, non-nuclear and threshold. The chapters explore the evolution of thinking about nuclear weapons and the role these weapons play in national security planning, and question the official security rationales offered by the nuclear weapon states for the maintenance of nuclear capabilities. For the non-nuclear weapon states, the book presents an analysis of alternative ways of assuring security and foreign policy effectiveness. For the threshold states, it examines the regional contexts within which these states maintain their threshold status. This book transcends traditional East-West approaches to analysis of nuclear issues by giving equal prominence to the issues of nuclear proliferation and non-nuclearism. The book also provides a comprehensive analysis of how current approaches to nuclear weapons have evolved both within and among the groups of countries under study

  3. Nuclear power

    International Nuclear Information System (INIS)

    Porter, Arthur.

    1980-01-01

    This chapter of the final report of the Royal Commission on Electric Power Planning in Ontario updates its interim report on nuclear power in Ontario (1978) in the light of the Three Mile Island accident and presents the commission's general conclusions and recommendations relating to nuclear power. The risks of nuclear power, reactor safety with special reference to Three Mile Island and incidents at the Bruce generating station, the environmental effects of uranium mining and milling, waste management, nuclear power economics, uranium supplies, socio-political issues, and the regulation of nuclear power are discussed. Specific recommendations are made concerning the organization and public control of Ontario Hydro, but the commission concluded that nuclear power is acceptable in Ontario as long as satisfactory progress is made in the disposal of uranium mill tailings and spent fuel wastes. (LL)

  4. Nuclear knowledge management

    International Nuclear Information System (INIS)

    2007-01-01

    The management of nuclear knowledge has emerged as a growing challenge in recent years. The need to preserve and transfer nuclear knowledge is compounded by recent trends such as ageing of the nuclear workforce, declining student numbers in nuclear-related fields, and the threat of losing accumulated nuclear knowledge. Addressing these challenges, the IAEA promotes a 'knowledge management culture' through: - Providing guidance for policy formulation and implementation of nuclear knowledge management; - Strengthening the contribution of nuclear knowledge in solving development problems, based on needs and priorities of Member States; - Pooling, analysing and sharing nuclear information to facilitate knowledge creation and its utilization; - Implementing effective knowledge management systems; - Preserving and maintaining nuclear knowledge; - Securing sustainable human resources for the nuclear sector; and - Enhancing nuclear education and training

  5. DYNAMICALLY MAINTAINING THE VISIBILITY GRAPH

    NARCIS (Netherlands)

    VEGTER, G

    1991-01-01

    An algorithm is presented to maintain the visibility graph of a set of N line segments in the plane in O(log2 N + K log N) time, where K is the total number of arcs of the visibility graph that are destroyed or created upon insertion or deletion of a line segment. The line segments should be

  6. Carbon storage in soil: how different land uses affect particulate organic matter composition. A molecular approach using nuclear magnetic resonance spectroscopy.

    Science.gov (United States)

    Panettieri, Marco; Courtier-Murias, Denis; Rumpel, Cornelia; Dignac, Marie-France; Doumert, Bertrand; Chabbi, Abad

    2017-04-01

    The future soil carbon stocks in a climate change scenario is being closely monitored. However, the huge edaphoclimatic variability impedes to disclose the mechanisms which underlie the cycle of accumulation/mineralization of soil organic matter (SOM). Soil environment could be described as a complex three phases matrix in which gases, liquids, and solids are not uniformly mixed, and in which microbes, fungi, vegetal residues, and roots are continuously interacting with the soil matrix and with each other. Molecular analyses on soil samples are crucial to estimate how stable those pools are and to predict which practices may accumulate larger C stocks. However, the study of land use impact through molecular characterization of a complex mixture like SOM is a challenge that requires a multidisciplinary approach. The present study applied a combination of soil physical fractionation (separation by density of the particulate organic matter (POM) within water stable aggregate fractions) followed by nuclear magnetic resonance (NMR) spectroscopy as a way to overcome spatial variability and to quantify the changes in the composition of SOM induced by land-use changes. The objective of the study was to assess, at a molecular level, the impact of different land managements, i.e. the introduction of temporary (ley) grassland into cropping cycles, on the chemical composition of SOM. Soil samples were collected at the long-term experimental observatory in Lusignan (http://www.soere-acbb.com/), in which control plots under permanent grassland, permanent cropland, and bare fallow are part of the experiment. To improve the signal-to-noise ratio (especially in the aromatic-C region), samples were analyzed using a ramped cross polarization-single pulse/magic angle spinning (CPSP/MAS) experiment. Peak integrals of different spectral regions (indicating different compound classes) were compared between treatments and two different molecular mixing models, calibrated against standard

  7. 10 CFR 1304.111 - Maintaining records of disclosures.

    Science.gov (United States)

    2010-01-01

    ....111 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.111 Maintaining records of... a record to any person or agency. Such accounting also shall contain the name and address of the... the Freedom of Information Act (5 U.S.C. 552). (b) The Board shall retain the accounting of each...

  8. Guidelines and workbook for assessment of organization and administration of utilities seeking operating license for Nuclear Power Plant. Workbook for assessment of organization and management. Volume 2

    International Nuclear Information System (INIS)

    Thurber, J.A.; Olson, J.; Osborn, R.N.; Sommers, P.; Widrig, R.D.

    1985-08-01

    Purpose of the Workbook is to guide the NRC reviewer through a systematic review and assessment of a proposed organization and administration. The Workbook outlines criteria for evaluating a written organization/administration plan and ensures consistent and comprehensive review of organization plans and site visit materials. The Workbook is designed to assist the NRC reviewer in assembling and analyzing objective information deemed necessary for judging acceptability of the plan, but it does not itself make the judgment

  9. Nuclear Safety Charter

    International Nuclear Information System (INIS)

    2008-01-01

    The AREVA 'Values Charter' reaffirmed the priority that must be given to the requirement for a very high level of safety, which applies in particular to the nuclear field. The purpose of this Nuclear Safety Charter is to set forth the group's commitments in the field of nuclear safety and radiation protection so as to ensure that this requirement is met throughout the life cycle of the facilities. It should enable each of us, in carrying out our duties, to commit to this requirement personally, for the company, and for all stakeholders. These commitments are anchored in organizational and action principles and in complete transparency. They build on a safety culture shared by all personnel and maintained by periodic refresher training. They are implemented through Safety, Health, and Environmental management systems. The purpose of these commitments, beyond strict compliance with the laws and regulations in force in countries in which we operate as a group, is to foster a continuous improvement initiative aimed at continually enhancing our overall performance as a group. Content: 1 - Organization: responsibility of the group's executive management and subsidiaries, prime responsibility of the operator, a system of clearly defined responsibilities that draws on skilled support and on independent control of operating personnel, the general inspectorate: a shared expertise and an independent control of the operating organization, an organization that can be adapted for emergency management. 2 - Action principles: nuclear safety applies to every stage in the plant life cycle, lessons learned are analyzed and capitalized through the continuous improvement initiative, analyzing risks in advance is the basis of Areva's safety culture, employees are empowered to improve nuclear Safety, the group is committed to a voluntary radiation protection initiative And a sustained effort in reducing waste and effluent from facility Operations, employees and subcontractors are treated

  10. Adaptive management system for hazardous technology organizations: safety culture as an assumption of nuclear excellence; Sistema de gestao adaptativo para organizacoes com tecnologia perigosa: a cultura de seguranca como pressuposto de excelencia nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Obadia, Isaac Jose

    2004-07-01

    This work develops a management system for organizations of sectors that deal with hazardous technology - aviation, petrochemical and nuclear, among others - where safety represents a critical factor to organizational excellence. The system consists of a management process based on the Model of Excellence of the Brazilian Quality Award to which the organisation's safety culture is integrated under an adaptive approach and safety is incorporated as an strategic dimension of excellence. The complexity involved in the organizational changing process, established by the implementation of the system, has been considered in the facilitated change type of intervention, also developed in this work, through a case study performed in a nuclear research and technological development installation. The developed system makes possible as effective safety culture improvement and simultaneously facilitates an effective implementation of the management process in search of excellence. (author)

  11. Desirable factors for maintaining normal BMI of urban affluent women of Delhi.

    Science.gov (United States)

    Gupta, Anu Taneja; Siddhu, Anupa

    2015-01-01

    The study aimed to identify desirable social, familial, reproductive, dietary, and lifestyle factors for maintaining normal body mass index (BMI) of urban affluent women (25-45 years) in Delhi, India. A total of 387 urban affluent women with at least one living child participated in this cross-sectional study conducted from March 2008 to April 2010. Women were classified into four BMI categories on the basis of World Health Organization (WHO; 2004) classification for Asians. Significant factors for maintaining normal BMI were: Younger age, less parity, nuclear family, normal weight status of parents, postpartum weight gain between 2 and 3 kg, regularity in taking meals, fixed meal size, self-perceived normal weight, and shorter sitting time and television viewing time. Multivariate regression analysis identified five determining factors for maintaining BMI, which are normal weight of father, self-perceived normal weight, fixed meal size, sitting time less than 6 h/day, and television viewing time less than 1 h/day. By small lifestyle modifications, normal BMI can be maintained.

  12. Nuclear Waste Management Organization: moving forward together - program update: Canada's plan for the long-term management of used nuclear fuel

    International Nuclear Information System (INIS)

    Nash, K.

    2011-01-01

    In June 2007, the Government of Canada selected Adaptive Phased Management as Canada's plan for safeguarding the public and environment over the very long time in which used nuclear fuel must be managed. The plan requires that Canada's used nuclear fuel be safely and securely contained and isolated from people and the environment in a deep geological repository in a suitable rock formation. In May 2010, the NWMO published a process for identifying an informed and willing community to host the project and currently a number of communities in northwestern Ontario and Saskatchewan have expressed interest in learning about the project. The NWMO anticipates that it will take between seven and ten years to decide on where to locate the deep geological repository and associated facilities. By international standards, this is an ambitious timeline. Ultimately, there will have to be a compelling demonstration of willingness expressed by the citizens of any interested community after a long period of site assessment, and learning about the project, before it is selected to host the project. The presentation will cover the history leading to the 2007 government decision and the full range of activities being undertaken to implement that decision.

  13. Disturbance maintains alternative biome states.

    Science.gov (United States)

    Dantas, Vinícius de L; Hirota, Marina; Oliveira, Rafael S; Pausas, Juli G

    2016-01-01

    Understanding the mechanisms controlling the distribution of biomes remains a challenge. Although tropical biome distribution has traditionally been explained by climate and soil, contrasting vegetation types often occur as mosaics with sharp boundaries under very similar environmental conditions. While evidence suggests that these biomes are alternative states, empirical broad-scale support to this hypothesis is still lacking. Using community-level field data and a novel resource-niche overlap approach, we show that, for a wide range of environmental conditions, fire feedbacks maintain savannas and forests as alternative biome states in both the Neotropics and the Afrotropics. In addition, wooded grasslands and savannas occurred as alternative grassy states in the Afrotropics, depending on the relative importance of fire and herbivory feedbacks. These results are consistent with landscape scale evidence and suggest that disturbance is a general factor driving and maintaining alternative biome states and vegetation mosaics in the tropics. © 2015 John Wiley & Sons Ltd/CNRS.

  14. Designing for nuclear power plant maintainability and operability

    International Nuclear Information System (INIS)

    Pedersen, T.J.

    1998-01-01

    Experience has shown that maintenance and operability aspects must be addressed in the design work. ABB Atom has since long an ambition of achieving optimised, overall plant designs, and efficient feedback of growing operating experience has stepwise eliminated shortcomings, and yielded better and better plant operating performances. The records of the plants of the latest design versions are very good; four units in Sweden have operated at an energy availability of 90.1%, and the two Olkiluoto units in Finland at a load factor of 92.7%, over the last decade. The occupational radiation exposures have also been at a low level. The possibilities for implementing 'lessons learned' in existing plants are obviously limited by practical constraints. In Finland and Sweden, significant modernisations are still underway, however, involving replacement of mechanical equipment, and upgrading and backfitting of I and C systems on a large scale, in most of the plants. The BWR 90 design focuses on meeting requirements from utilities as well as new regulatory requirements, with a particular emphasis on the consequences of severe accidents; there shall be no large releases to the environment. Other design improvements involve: all-digital I and C systems and enhanced human factors engineering to improve work environment for operators, optimisation of buildings and containment to decrease construction time and costs, and selection of materials as well as maintenance of operating procedures to reduce radiation exposures even further. The BWR 90 design was offered to Finland in the early 1990s, but development work continues. It has been selected by a number of European utilities for assessing its conformance with the European Utility Requirements (EUR), aiming at a specific EUR Volume 3 for the BWR 90. Some characteristics of the ABB BWRs, with emphasis on features of importance for achieving improved economy and enhanced safety, are described below. (author)

  15. Essay on nuclear law

    International Nuclear Information System (INIS)

    Puig, Diva

    1994-01-01

    This book is divided in seven parts, covering international organizations in nuclear energy. agreements, nuclear laws and environment, national legislation program and Uruguayan legislation. The texts of the nuclear laws in Uruguay are reproduced, and several aspects on nuclear energy are discussed

  16. International co-operation through scientific and technical nuclear societies

    International Nuclear Information System (INIS)

    Manning Muntzing, L.

    1983-01-01

    As an international organization the American Nuclear Society (ANS) has played an active role in international co-operation of nuclear technology exchange since its establishment in 1954. The ANS has a membership of over 13,000 individuals, of whom approximately 1200 live overseas in forty countries. To carry out the goals of the Society, local sections have been established. Currently the ANS maintains 48 local sections in the United States of America and 8 overseas local sections in Africa, Asia, Europe and South America. The ANS also has formal agreements for co-operation with The Asociacion Argentina de Tecnologia Nuclear (AATN), the Israel Nuclear Society (INS), and the Chinese Nuclear Society (CNS). In 1977 the Japan Atomic Energy Society (JAES), the European Nuclear Society (ENS), and the ANS co-operation in sponsoring the First International Conference on Transfer of Nuclear Technology (ICONTT I) in Tehran, Iran. In 1982, the Second International Conference on Transfer of Nuclear Technology (ICONTT II), Buenos Aires, Argentina, was sponsored through the co-operation of the AATN, the ENS and the ANS. The ANS and its overseas sections sponsor the Pacific Basin Conference approximately every three years to discuss nuclear matters of concern to the countries around the Pacific Ocean. In 1981 the ANS held a Nuclear Technology Exhibit in Beijing, the People's Republic of China. In addition to meetings, the ANS is extensively involved in the co-operative exchange of applied nuclear research information through its publications. Nuclear Technology, a technical journal, is published monthly under joint ownership of the ENS and the ANS. The ANS has been a leader in voluntary standards development since 1958. In its dedication to the co-operation of international nuclear technology the ANS maintains a comprehensive international exchange of nuclear standards

  17. NMG documentation, part 3: maintainer`s guide

    Energy Technology Data Exchange (ETDEWEB)

    Fritsch, F.N.; Dickinson, R.P. Jr.

    1996-07-01

    This is the third of a three-part report documenting NMG, the Numerical Mathematics Guide. Part I is aimed at the user of the systenL It contains an introduction, with an out- line of the complete report, and Chapter 1, User`s Point of View. Part II is aimed at the programmer and contains Chapter 2, How It Works. Part III is aimed at the maintainer of NMG and contains Chapter 3, Maintenance, and Chapter 4, Validation. Because its contents are so specialized, Part III will receive only limited distribution. Note that each chapter has its own page numbering and table of contents.

  18. The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control.

    Science.gov (United States)

    Zeng, Liyong; Wan, Yihan; Li, Dan; Wu, Jing; Shao, Mengle; Chen, Jiong; Hui, Lijian; Ji, Hongbin; Zhu, Xueliang

    2013-10-18

    Mammalian eIF3 is composed of 13 subunits and is the largest eukaryotic initiation factor. eIF3 plays a key role in protein biosynthesis. However, it is not fully understood how different subunits contribute to the structural integrity and function of the eIF3 complex. Whether eIF3 is essential for embryonic development and homeostasis is also not known. Here, we show that eIF3m null embryos are lethal at the peri-implantation stage. Compound heterozygotes (eIF3m(flox)(/-)) or FABP4-Cre-mediated conditional knock-out mice are lethal at mid-gestation stages. Although the heterozygotes are viable, they show markedly reduced organ size and diminished body weight. Acute ablation of eIF3m in adult mouse liver leads to rapidly decreased body weight and death within 2 weeks; these effects are correlated with a severe decline of protein biogenesis in the liver. Protein analyses reveal that eIF3m deficiency significantly impairs the integrity of the eIF3 complex due to down-regulation of multiple other subunits. Two of the subunits, eIF3f and eIF3h, are stabilized by eIF3m through subcomplex formation. Therefore, eIF3m is required for the structural integrity and translation initiation function of eIF3. Furthermore, not only is eIF3m an essential gene, but its expression level is also important for mouse embryonic development and the control of organ size.

  19. Co-operation agreement between the European Organization for Nuclear Research (CERN) and the Government of People's Republic of Bangladesh concerning Education, Scientific and Technical Co-operation in High-Energy Physics

    CERN Document Server

    2014-01-01

    Co-operation agreement between the European Organization for Nuclear Research (CERN) and the Government of People's Republic of Bangladesh concerning Education, Scientific and Technical Co-operation in High-Energy Physics

  20. Evaluating bio environmental effects of Bushehr Nuclear Power Plant on water and aquatic organism of Persian Gulf

    International Nuclear Information System (INIS)

    Ayatti, F.

    2000-01-01

    The operation of nuclear power plants is always subjected to emission of some radioactive materials in the form of gaseous, liquids and solids in the environment. The heat from condenser coolant discharged to the sea can have some adverse effects on biological systems as thermal pollution. In this project, the radiation and thermal effects on Bushehr Nuclear Power Plants on aquatic animals in Persian Gulf were studied. The mathematical models for atmospheric dispersion of pollutant and pathways of radioactive materials from air to sea water and from sea to animals and human bodies were considered. some environmental samples from Persian Gulf were measured for radioactivity using high-purity Ge/Li detectors and Gamma-spectroscopy. The results indicates that the erection of B usher Nuclear Power Plants and its operation in the normal operation can have no adverse effects on environment, and also its thermal pollution is of no importance due to low area for coolant discharges

  1. Demystifying nuclear power: the linear non-threshold model and its use for evaluating radiation effects on living organisms

    Energy Technology Data Exchange (ETDEWEB)

    Ramos, Alexandre F.; Vasconcelos, Miguel F.; Vergueiro, Sophia M. C.; Lima, Suzylaine S., E-mail: alex.ramos@usp.br [Universidade de São Paulo (USP), SP (Brazil). Núcleo Interdisciplinar de Modelagem de Sistemas Complexos

    2017-07-01

    Recently, a new variable has been introduced on nuclear power expansion policy: public opinion. That variable challenges the nuclear community to develop new programs aiming to educate society sectors interested on energy generation and not necessarily familiarized with concepts of the nuclear eld. Here we approach this challenge by discussing how a misconception about the use of theories in science has misled the interpretation of the Chernobyl's accident consequences. That discussion have been presented for students from fields related with Environmental Sciences and Humanities and have helped to elucidate that an extrapolation such as the Linear Non-Threshold model is a hypothesis to be tested experimentally instead of a theoretical tool with predictive power. (author)

  2. Demystifying nuclear power: the linear non-threshold model and its use for evaluating radiation effects on living organisms

    International Nuclear Information System (INIS)

    Ramos, Alexandre F.; Vasconcelos, Miguel F.; Vergueiro, Sophia M. C.; Lima, Suzylaine S.

    2017-01-01

    Recently, a new variable has been introduced on nuclear power expansion policy: public opinion. That variable challenges the nuclear community to develop new programs aiming to educate society sectors interested on energy generation and not necessarily familiarized with concepts of the nuclear eld. Here we approach this challenge by discussing how a misconception about the use of theories in science has misled the interpretation of the Chernobyl's accident consequences. That discussion have been presented for students from fields related with Environmental Sciences and Humanities and have helped to elucidate that an extrapolation such as the Linear Non-Threshold model is a hypothesis to be tested experimentally instead of a theoretical tool with predictive power. (author)

  3. Introducing Knowledge Management in Study Program of Nuclear Engineering

    International Nuclear Information System (INIS)

    Pleslic, S.

    2012-01-01

    Nuclear engineering is the branch of engineering concerning application of the fission as well as the fusion of atomic nuclei, and the application of other sub-atomic physics, based on the principles of nuclear physics. In the sub-field of nuclear fission there are many investigations of interactions and maintaining of systems and components like nuclear reactors and nuclear power plants. The field also includes the study of different applications of ionizing radiation (medicine, agriculture...), nuclear safety, the problems of thermodynamics transport, nuclear materials and nuclear fuels, and other related technologies like radioactive waste management. In the area of nuclear science and engineering a big amount of knowledge has been accumulated over the last decades. Different levels of nuclear knowledge were considered in different ways and they were taught to different parts of population as a general human culture and as a general scientific-technical-technological culture (high schools, nuclear information centres, training centres, universities...). An advanced level of nuclear knowledge has been accumulated by many experienced workers, specialists and experts in all nuclear and nuclear-related fields and applications. In the last 20 years knowledge management has established itself as a discipline of enabling individuals, teams and whole organizations to create, share and apply knowledge collectively and systematically, with goal to better achieve their objectives. Also, knowledge management became key strategic approach for management of intellectual assets and knowledge that can improve safety, efficiency and innovation, and lead to preserve and enhance current knowledge. Knowledge management could be applied in education, training, networking, human resource development and capacity building, sharing, pooling and transferring knowledge form centres of knowledge to centres of growth. Considering the critical importance of nuclear knowledge it is important

  4. Chemical effects associated to (n, γ) nuclear reactions in diluted aqueous solutions of liquid or frozen organic halogenides

    International Nuclear Information System (INIS)

    Bermudez Rodriguez, I.M.

    1985-09-01

    Chemical effects associated to nuclear transformation 37 Cl (n, γ) 38 Cl or 127 I (n, γ) 128 I in solid or liquid aqueous solutions of ethyl iodide, trichloro-ethylene, thyroxine or DDT irradiated in a nuclear reactor are studied. The retention of radiohalogen under its initial chemical shape decrease with solute concentration in liquid phase but is almost constant with solute dilution in the solid phase. Potential applications in neutron activation analysis evidencing halogenated molecules in irradiated media are discussed. 57 refs [fr

  5. Themes in nuclear law; Temas de Derecho Nuclear

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    The nuclear law was analyzed during a workshop. The main aspects were: the law of population to access to information on nuclear energy and the relationship between the Regulator Organism and the nuclear power plants managers.

  6. ESRS guidelines for software safety reviews. Reference document for the organization and conduct of Engineering Safety Review Services (ESRS) on software important to safety in nuclear power plants

    International Nuclear Information System (INIS)

    2000-01-01

    The IAEA provides safety review services to assist Member States in the application of safety standards and, in particular, to evaluate and facilitate improvements in nuclear power plant safety performance. Complementary to the Operational Safety Review Team (OSART) and the International Regulatory Review Team (IRRT) services are the Engineering Safety Review Services (ESRS), which include reviews of siting, external events and structural safety, design safety, fire safety, ageing management and software safety. Software is of increasing importance to safety in nuclear power plants as the use of computer based equipment and systems, controlled by software, is increasing in new and older plants. Computer based devices are used in both safety related applications (such as process control and monitoring) and safety critical applications (such as reactor protection). Their dependability can only be ensured if a systematic, fully documented and reviewable engineering process is used. The ESRS on software safety are designed to assist a nuclear power plant or a regulatory body of a Member State in the review of documentation relating to the development, application and safety assessment of software embedded in computer based systems important to safety in nuclear power plants. The software safety reviews can be tailored to the specific needs of the requesting organization. Examples of such reviews are: project planning reviews, reviews of specific issues and reviews prior final acceptance. This report gives information on the possible scope of ESRS software safety reviews and guidance on the organization and conduct of the reviews. It is aimed at Member States considering these reviews and IAEA staff and external experts performing the reviews. The ESRS software safety reviews evaluate the degree to which software documents show that the development process and the final product conform to international standards, guidelines and current practices. Recommendations are

  7. Pools and fluxes of organic matter in a boreal landscape: implications for a safety assessment of a repository for nuclear waste.

    Science.gov (United States)

    Kumblad, Linda; Söderbäck, Björn; Löfgren, Anders; Lindborg, Tobias; Wijnbladh, Erik; Kautsky, Ulrik

    2006-12-01

    To provide information necessary for a license application for a deep repository for spent nuclear fuel, the Swedish Nuclear Fuel and Waste Management Co is carrying out site investigations, including extensive studies of different parts of the surface ecosystems, at two sites in Sweden. Here we use the output from detailed modeling of the carbon dynamics in the terrestrial, limnic and marine ecosystems to describe and compare major pools and fluxes of organic matter in the Simpevarp area, situated on the southeast coast of Sweden. In this study, organic carbon is used as a proxy for radionuclides incorporated into organic matter. The results show that the largest incorporation of carbon into living tissue occurs in terrestrial catchments. Carbon is accumulated in soil or sediments in all ecosystems, but the carbon pool reaches the highest values in shallow near-land marine basins. The marine basins, especially the outer basins, are dominated by large horizontal water fluxes that transport carbon and any associated contaminants into the Baltic Sea. The results suggest that the near-land shallow marine basins have to be regarded as focal points for accumulation of radionuclides in the Simpevarp area, as they receive a comparatively large amount of carbon as discharge from terrestrial catchments, having a high NPP and a high detrital accumulation in sediments. These focal points may constitute a potential risk for exposure to humans in a future landscape as, due to post-glacial land uplift, previous accumulation bottoms are likely to be used for future agricultural purposes.

  8. Developing and maintaining instructor capabilities

    International Nuclear Information System (INIS)

    Flynn, W.P.; Smith, G.

    1985-01-01

    The New York Power Authority, after surveying available courses, decided to develop an in-house instructor training program. Following the principles of the Systems Approach to Training the course embodied the results of a job analysis resulting in a program containing instruction in Educational Philosophy, the Systems Approach to Training, Methods and Media, and Testing. The course content is covered through classroom instruction, on-the-job training, instructor evaluations, and assignments. Instructors completing the program continue to maintain skills with inservice training

  9. Nuclear accidents

    International Nuclear Information System (INIS)

    1987-01-01

    On 27 May 1986 the Norwegian government appointed an inter-ministerial committee of senior officials to prepare a report on experiences in connection with the Chernobyl accident. The present second part of the committee's report describes proposals for measures to prevent and deal with similar accidents in the future. The committee's evaluations and proposals are grouped into four main sections: Safety and risk at nuclear power plants; the Norwegian contingency organization for dealing with nuclear accidents; compensation issues; and international cooperation

  10. Nuclear medicine

    International Nuclear Information System (INIS)

    Blanquet, Paul; Blanc, Daniel.

    1976-01-01

    The applications of radioisotopes in medical diagnostics are briefly reviewed. Each organ system is considered and the Nuclear medicine procedures pertinent to that system are discussed. This includes, the principle of the test, the detector and the radiopharmaceutical used, the procedure followed and the clinical results obtained. The various types of radiation detectors presently employed in Nuclear Medicine are surveyed, including scanners, gamma cameras, positron cameras and procedures for obtaining tomographic presentation of radionuclide distributions [fr

  11. Differences in Nuclear DNA Organization Between Lymphocytes, Hodgkin and Reed–Sternberg Cells Revealed by Structured Illumination Microscopy

    NARCIS (Netherlands)

    Righolt, C.H.; Guffei, A.; Knecht, H.; Young, I.T.; Stallinga, S.; Van Vliet, L.J.; Mai, S.

    2014-01-01

    Advances in light microscopy have enabled the visualization of DNA in the interphase nucleus with more detail than is visible with conventional light microscopy. The nuclear architecture is assumed to be different in cancer cells compared to normal cells. In this paper we have studied, for the first

  12. Development of reliability-based safety enhancement technology; development of organization concept model in nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Chang Hyun; Kim, Ju Youl; Kim, Yoon Ik; Yang, Hui Chang; Lee, Yong Sik; Kim, Se Hyung [Seoul National University, Seoul (Korea)

    2002-03-01

    The influences of organizational factors on safety of nuclear power plants are mentioned in the early 1970s and noticed after being focused on in the accident report of TMI in 1979. These needs let us implement this research and the purposes of this research are to assess the organizational influences and to develop the organizational conceptual model to establish the basis of identifying the organizational factors, using this model to contribute to enhance safety and economics in nuclear power plants. Eventually research on the organizational influences is expected to have two effects, which are to improve safety through identifying potential causes of accidents and to elevate economics as a new approach to more efficient operation of nuclear power plants. In this study, recent studies were surveyed on the organizational conceptual model, the identification of organizational factors, assessment of organizational influences and evaluation methods of organizational factors and organizational influences among the overseas and domestic researches. In addition specific characteristics of domestic nuclear power plants were tried to identify through plant visit and an evaluation method of organizational influences on component maintenance and human performance were developed and presented. 71 refs., 40 figs., 18 tabs. (Author)

  13. US nuclear survey

    International Nuclear Information System (INIS)

    2002-08-01

    This document gives a broad overview of the organization of nuclear activities in the USA: nuclear park and availability (reactors, R and D), fuel cycle (uranium enrichment, wastes management (storage and disposal sites)). (J.S.)

  14. ABACC's nuclear accounting area

    International Nuclear Information System (INIS)

    Nicolas, Ruben O.

    2001-01-01

    The functions and activities of the Brazilian-Argentine Agency for the Accounting and Control of Nuclear Materials (ABACC) accounting area is outlined together with a detailed description of the nuclear accounting system used by the bilateral organization

  15. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... MRI. top of page What are some common uses of the procedure? Children's (pediatric) nuclear medicine imaging ... at birth) or that develop during childhood. Physicians use nuclear medicine imaging to evaluate organ systems, including ...

  16. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... nuclear medicine imaging to evaluate organ systems, including the: kidneys and bladder. bones. liver and gallbladder. gastrointestinal tract. heart. lungs. brain. thyroid. Nuclear medicine scans are typically used to ...

  17. New discovery: quantization of atomic and nuclear rest mass differences and self-organization of atoms and nuclei

    International Nuclear Information System (INIS)

    Gareev, F.A.; Zhidkova, I.E.; )

    2007-01-01

    Full text: We come to the conclusion that all atomic models based on either the Newton equation and the Kepler laws, or the Maxwell equations, or the Schroedinger and Dirac equations are in reasonable agreement with experimental data. We can only suspect that these equations are grounded on the same fundamental principles which are not known or these equations can be transformed into each other. We proposed a new mechanism of LENR: cooperative processes in the whole system - nuclei + atoms + condensed matter - nuclear reactions in plasma - can occur at smaller threshold energies than the corresponding ones on free constituents. We were able to quantize phenomenologically the first time the differences between atomic and nuclear rest masses by the formula: ΔΔM = n 1 /n 2 ·0.0076294 (in MeV/ ), n i =1,.2,3... Note that this quantization rule is justified for atoms and nuclei with different A, N and Z and the nuclei and atoms represent a coherent synchronized open systems - a complex of coupled oscillators (resonators). The cooperative resonance synchronization mechanisms are responsible for explanation of how the electron volt world can influence on the nuclear mega electron volt world. It means that we created new possibilities for inducing and controlling nuclear reactions by atomic processes grounded on the fundamental low of physics - conservation law of energy. The results of these research field can provide new ecologically pure mobile sources of energy independent from oil, gas and coal, new substances, and technologies. For example, this discovery gives us a simple and cheep method for utilization of nuclear waste

  18. Safety organization

    International Nuclear Information System (INIS)

    Lutz, M.

    1984-06-01

    After a rapid definition of a nuclear basis installation, the national organization of nuclear safety in France is presented, as also the main organizations concerned and their functions. This report shows how the licensing procedure leading to the construction and exploitation of such installations is applied in the case of nuclear laboratories of research and development: examinations of nuclear safety problems are carried out at different levels: - centralized to define the frame out of which the installation has not to operate, - decentralized to follow in a more detailed manner its evolution [fr

  19. Decontamination and decommissioning in the Nuclear Research Institute Rez plc

    Energy Technology Data Exchange (ETDEWEB)

    Kovarik, P.; Podlaha, J. [Nuclear Research Institute Rez plc, Rez (Czech Republic)

    2007-04-15

    The Nuclear Research Institute Rez (NRI) is a leading institution in the area of Decontamination and Decommissioning in the Czech Republic. The NRI has maintained a dominant position in the nuclear program of the former Czechoslovakia since it was established in 1955 as a state-owned research organization. In December 1992 the NRI has been transformed into a joint-stock company. The Institute's activity encompasses nuclear physics, radiochemistry, experiments at the research reactor and many other topics. At present, research activities are mainly targeted at assisting the nuclear safety regulating body, power plant operator and nuclear facilities contractors. Significant attention is also paid to the use of nuclear technology outside the nuclear power sector. NRI operates 2 research nuclear reactors, hot cell facility, research laboratories, technology for radioactive waste management, radionuclide constructions for irradiation, and others. After 50 years of activities in the nuclear field, there are many environmental liabilities that shall be remedied. Such remedies are broken down to three areas: 1. Decommissioning of old obsolete facilities (e.g. decay tanks, liquid RAW storage tanks, old RAW treatment technology, special sewage system), 2. Processing of RAW resulting from operation and dismantling of nuclear facilities and 3. Elimination of spent fuel from research nuclear reactors. The goal is to remedy the environmental liabilities and eliminate the potential negative impact on the environment. Remediation of the environmental liabilities started in 2003 and should be finished in 2012. (orig.)

  20. Nuclear questions

    Energy Technology Data Exchange (ETDEWEB)

    Durrani, M. [Physics World (United Kingdom)

    2006-01-01

    The future of nuclear power has returned to centre stage. Freezing weather on both sides of the Atlantic and last month's climate-change talks in Montreal have helped to put energy and the future of nuclear power right back on the political agenda. The issue is particularly pressing for those countries where existing nuclear stations are reaching the end of their lives. In the UK, prime minister Tony Blair has commissioned a review of energy, with a view to deciding later this year whether to build new nuclear power plants. The review comes just four years after the Labour government published a White Paper on energy that said the country should keep the nuclear option open but did not follow this up with any concrete action. In Germany, new chancellor and former physicist Angela Merkel is a fan of nuclear energy and had said she would extend the lifetime of its nuclear plants beyond 2020, when they are due to close. However, that commitment has had to be abandoned, at least for the time being, following negotiations with her left-wing coalition partners. The arguments in favour of nuclear power will be familiar to all physicists - it emits almost no carbon dioxide and can play a vital role in maintaining a diverse energy supply. To over-rely on imported supplies of oil and gas can leave a nation hostage to fortune. The arguments against are equally easy to list - the public is scared of nuclear power, it generates dangerous waste with potentially huge clean-up costs, and it is not necessarily cheap. Nuclear plants could also be a target for terrorist attacks. Given political will, many of these problems can be resolved, or at least tackled. China certainly sees the benefits of nuclear power, as does Finland, which is building a new 1600 MW station - the world's most powerful - that is set to open in 2009. Physicists, of course, are essential to such developments. They play a vital role in ensuring the safety of such plants and developing new types of

  1. Nuclear fuel reprocessing

    International Nuclear Information System (INIS)

    White, D.

    1981-01-01

    A simple friction device for cutting nuclear fuel wrappers comprising a thin metal disc clamped between two large diameter clamping plates. A stream of gas ejected from a nozzle is used as coolant. The device may be maintained remotely. (author)

  2. Maintaining consistency in distributed systems

    Science.gov (United States)

    Birman, Kenneth P.

    1991-01-01

    In systems designed as assemblies of independently developed components, concurrent access to data or data structures normally arises within individual programs, and is controlled using mutual exclusion constructs, such as semaphores and monitors. Where data is persistent and/or sets of operation are related to one another, transactions or linearizability may be more appropriate. Systems that incorporate cooperative styles of distributed execution often replicate or distribute data within groups of components. In these cases, group oriented consistency properties must be maintained, and tools based on the virtual synchrony execution model greatly simplify the task confronting an application developer. All three styles of distributed computing are likely to be seen in future systems - often, within the same application. This leads us to propose an integrated approach that permits applications that use virtual synchrony with concurrent objects that respect a linearizability constraint, and vice versa. Transactional subsystems are treated as a special case of linearizability.

  3. The Use of Questionnaires in Safety Culture Studies in High Reliability Organizations. Literature Review and an Application in the Spanish Nuclear Sector

    International Nuclear Information System (INIS)

    German, S.; Navajas, J.; Silla, I.

    2014-01-01

    This report examines two aspects related to the use of questionnaires in safety culture research conducted in high reliability organizations. First, a literature review of recent studies that address safety culture through questionnaires is presented. Literature review showed that most studies used only questionnaires as a research technique, were cross-sectional, applied paper-based questionnaires, and were conducted in one type of high reliability organization. Second, a research project on safety culture that used electronic surveys in a sample of experts on safety culture is discussed. This project, developed by CISOT-CIEMAT research institute, was carry out in the Spanish nuclear sector and illustrates relevant aspects of the methodological design and administration processes that must be considered to encourage participation in the study.. (Author)

  4. Study of the organizational structure of nuclear power plants and their coordination with supervisory organizations and structures. Pt. 1

    International Nuclear Information System (INIS)

    1989-01-01

    In the last few years the management of nuclear power plants as well as the supervising administration of the nuclear industry in Germany has focused more on emergency preparedness. The skills have been improved, but there are also improvements under way, yet. The study gives an overview about the status of emergency preparedness in German power plants, about the legal framework for emergency preparedness and about the elements of an effective emergency preparedness planning. However, it does not deal with technical accident management but with the organisational aspects of emergency planning. Also, the study gives a short outlook for future trends of development in the field of emergency preparedness in Germany. Major trends are the standardisation of organisational concepts, more training and more national and international feed back of know how on the topic. Yet, there is still some research work to be done, mainly to develop overall organisational standards and to profit from international experiences. (orig.) [de

  5. Nuclear energy and security

    International Nuclear Information System (INIS)

    Blejwas, Thomas E.; Sanders, Thomas L.; Eagan, Robert J.; Baker, Arnold B.

    2000-01-01

    Nuclear power is an important and, the authors believe, essential component of a secure nuclear future. Although nuclear fuel cycles create materials that have some potential for use in nuclear weapons, with appropriate fuel cycles, nuclear power could reduce rather than increase real proliferation risk worldwide. Future fuel cycles could be designed to avoid plutonium production, generate minimal amounts of plutonium in proliferation-resistant amounts or configurations, and/or transparently and efficiently consume plutonium already created. Furthermore, a strong and viable US nuclear infrastructure, of which nuclear power is a large element, is essential if the US is to maintain a leadership or even participatory role in defining the global nuclear infrastructure and controlling the proliferation of nuclear weapons. By focusing on new fuel cycles and new reactor technologies, it is possible to advantageously burn and reduce nuclear materials that could be used for nuclear weapons rather than increase and/or dispose of these materials. Thus, the authors suggest that planners for a secure nuclear future use technology to design an ideal future. In this future, nuclear power creates large amounts of virtually atmospherically clean energy while significantly lowering the threat of proliferation through the thoughtful use, physical security, and agreed-upon transparency of nuclear materials. The authors must develop options for policy makers that bring them as close as practical to this ideal. Just as Atoms for Peace became the ideal for the first nuclear century, they see a potential nuclear future that contributes significantly to power for peace and prosperity

  6. Review of Policy Documents for Nuclear Safety and Regulation

    International Nuclear Information System (INIS)

    Kim, Woong Sik; Choi, Kwang Sik; Choi, Young Sung; Kim, Hho Jung; Kim, Ho Ki

    2006-01-01

    The goal of regulation is to protect public health and safety as well as environment from radiological hazards that may occur as a result of the use of atomic energy. In September 1994, the Korean government issued the Nuclear Safety Policy Statement (NSPS) to establish policy goals of maintaining and achieving high-level of nuclear safety and also help the public understand the national policy and a strong will of the government toward nuclear safety. It declares the importance of establishing safety culture in nuclear community and also specifies five nuclear regulatory principles (Independence, Openness, Clarity, Efficiency and Reliability) and provides the eleven regulatory policy directions. In 2001, the Nuclear Safety Charter was declared to make the highest goal of safety in driving nuclear business clearer; to encourage atomic energy- related institutions and workers to keep in mind the mission and responsibility for assuring safety; to guarantee public confidence in related organizations. The Ministry of Science and Technology (MOST) also issues Yearly Regulatory Policy Directions at the beginning of every year. Recently, the third Atomic Energy Promotion Plan (2007-2011) has been established. It becomes necessary for the relevant organizations to prepare the detailed plans on such areas as nuclear development, safety management, regulation, etc. This paper introduces a multi-level structure of nuclear safety and regulation policy documents in Korea and presents some improvements necessary for better application of the policies

  7. Review of Policy Documents for Nuclear Safety and Regulation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Woong Sik; Choi, Kwang Sik; Choi, Young Sung; Kim, Hho Jung; Kim, Ho Ki [Korea Institute of Nuclear Safety, Taejon (Korea, Republic of)

    2006-07-01

    The goal of regulation is to protect public health and safety as well as environment from radiological hazards that may occur as a result of the use of atomic energy. In September 1994, the Korean government issued the Nuclear Safety Policy Statement (NSPS) to establish policy goals of maintaining and achieving high-level of nuclear safety and also help the public understand the national policy and a strong will of the government toward nuclear safety. It declares the importance of establishing safety culture in nuclear community and also specifies five nuclear regulatory principles (Independence, Openness, Clarity, Efficiency and Reliability) and provides the eleven regulatory policy directions. In 2001, the Nuclear Safety Charter was declared to make the highest goal of safety in driving nuclear business clearer; to encourage atomic energy- related institutions and workers to keep in mind the mission and responsibility for assuring safety; to guarantee public confidence in related organizations. The Ministry of Science and Technology (MOST) also issues Yearly Regulatory Policy Directions at the beginning of every year. Recently, the third Atomic Energy Promotion Plan (2007-2011) has been established. It becomes necessary for the relevant organizations to prepare the detailed plans on such areas as nuclear development, safety management, regulation, etc. This paper introduces a multi-level structure of nuclear safety and regulation policy documents in Korea and presents some improvements necessary for better application of the policies.

  8. European Nuclear Education Network Association - Support for nuclear education, training and knowledge management

    International Nuclear Information System (INIS)

    Ghitescu, Petre

    2009-01-01

    Developed in 2002-2003 the FP5 EURATOM project 'European Nuclear Engineering Network - ENEN' aimed to establish the basis for conserving nuclear knowledge and expertise, to create an European Higher Education Area for nuclear disciplines and to facilitate the implementation of the Bologna declaration in the nuclear disciplines. In order to ensure the continuity of the achievements and results of the ENEN project, on 22 September 2003, the European Nuclear Higher Education Area was formalized by creating the European Nuclear Education Network Association. ENEN Association goals are oriented towards universities by developing a more harmonized approach for education in the nuclear sciences and engineering in Europe, integrating European education and training in nuclear safety and radiation protection and achieving a better cooperation and sharing of resources and capabilities at the national and international level. At the same time it is oriented towards the end-users (industries, regulatory bodies, research centers, universities) by creating a secure basis of knowledge and skills of value to the EU. It maintains an adequate supply of qualified human resources for design, construction, operation and maintenance of nuclear infrastructures and plants. Also it maintains the necessary competence and expertise for the continued safe use of nuclear energy and applications of radiation in industry and medicine. In 2004-2005, 35 partners continued and expanded the started in FP 5 ENEN Association activities with the FP6 project 'NEPTUNO- Nuclear Education Platform for Training and Universities Organizations'. Thus ENEN established and implemented the European Master of Science in Nuclear Engineering, expanded its activities from education to training, organized and coordinated training sessions and pilot courses and included in its activities the Knowledge Management. At present, the ENEN Association gathers 45 universities, 7 research centers and one multinational company

  9. INDC list of correspondents for the exchange of nuclear data information and compilation of national nuclear data committees

    International Nuclear Information System (INIS)

    1987-09-01

    This list of INDC Correspondents, including information on currently existing National Nuclear Data Committees and their memberships, is compiled and published upon the request of the International Nuclear Data Committee with the objective to promote the interaction and enhance the awareness of nuclear data activities in IAEA Member States. It also serves as a basis for the distribution of documents originated by or for the International Nuclear Data Committee and includes the names of all recipients of INDC documents. The INDC Secretariat tries to maintain this list up-to-date in order to facilitate an efficient interchange of information on nuclear data topics. The report is presented in five sections. The first section contains a detailed description of the INDC distribution categories, distribution codes and document designator codes. The second section describes the aims, organization and objectives of individual national nuclear data committees. The third section lists names and addresses in alphabetical order within each state or international organization together with the assigned INDC document distribution code(s); where applicable committee membership and/or area of specialization are indicated. This is followed by four shorter lists, indicating the names of individuals in each distribution category, sorted by country or international organization, and the total number of individuals in each category. The final section provides the names of nuclear data committee members also listed by country or international organization

  10. Website WWW.INIS.UZ of the national INIS centre of Uzbekistan and WebSPIRS systems for nuclear republic organizations

    International Nuclear Information System (INIS)

    Kadirova, M.; Umaraliev, A.; Yuldashev, H.; Yahshilikov, A.

    2009-01-01

    Full text: Implementation of IAEA TC project (2007-2009) UZB/0/003 'Upgrading the National INIS centre of Uzbekistan' gives an opportunity to create the web-site of INIS Centre of Uzbekistan www.inis.uz, which can provide access to the INIS Data Base (DB) and information resources of the centre, as well as dissemination services on delivery of full-text Non-conventional literature (NCL) and publications, issued in Uzbekistan on nuclear subject and information from resource fund both for INP and for many organization of Uzbekistan with nuclear-physical profile. In Menu section of the website: INIS IAEA and INIS Centre of Uzbekistan, detailed information about INIS history and its creation and philosophy, about what is INIS, what INIS does, output products and services, provided by INIS is placed. Here, it is possible to find information about history of Uzbekistan INIS Centre, performing activities in the centre, services which centre enable to provide for users of INIS DB in all Uzbekistan nuclear organizations. Within the framework of project, activities on automation of Scientific-Technical Library (STL) of INP AS RU have been also implemented which is joined to International Nuclear Libraries Network (INLN) under IAEA, and therefore libraries must present their own electronic resources for general use. To provide the access to various electronic catalogues of the library and to the list of full-text documents and articles, storing in the Institute server, the Web Page of Scientific-Technical Library of INP has been developed, the entry for which is carried out from the web-site of Uzbekistan INIS Centre, specified in the Menu as INP Library. Library news is also reflected in this page. Upon the request of INIS users, within the frame of project, scientific-technical literature of IAEA publishing and several books of the other publishers have also received. In Uzbekistan INIS centre a lot of information materials, both in hard copy and on CD-ROM, as well as

  11. Nuclear power: which industrial approach will preserve a French asset?

    International Nuclear Information System (INIS)

    Machenaud, H.

    2012-01-01

    France's strategic decision in favor of nuclear energy in the 1970's has given rise to an organization of this industry with clearly defined roles and responsibilities for all parties. This has led to the mastering of industrial production of the whole chain from mining to fuel reprocessing and to waste disposal. Nuclear safety was at any stage of the chain the priority number one. The French nuclear industry is present on the international scene and thus maintain its know-how and capacities despite the ups and downs of the nuclear market. Today 240.000 people work in France in the nuclear sector. France has followed a consistent energy policy during the last 50 years and benefits from an important and homogeneous fleet of reactors which has generated a rich feedback experience on reactor operation. The tasks that face the French nuclear industry are: -) to comply with the requirements of the Complementary Safety Assessments that have been performed on all French nuclear facilities, -) to maintain and upgrade the power plants (most of them are facing their 3. decennial overhaul), -) to prepare the nuclear systems of tomorrow, and -) to export the French know-how

  12. Clear-cut and practice-oriented organization - the connecting link between man and nuclear power plant operation requirements. Eine eindeutige und praxisgerechte Organisation - das Bindeglied zwischen Mensch und Anforderungen des Kernkraftwerkbetriebes

    Energy Technology Data Exchange (ETDEWEB)

    Steiner, E.K. (Bayernwerk AG, Kernkraftwerk Grafenrheinfeld (Germany))

    1994-04-01

    Practice-oriented plant organization takes into account the human spheres of task and responsibility, training and qualification, communication and exchange of experience, setting of targets, management and control as well as motivation and loyalty. It constitutes the basis for meeting the demands on a safe and reliable nuclear power plant operation. This is demonstrated by the organization at the Grafenrheinfeld NPP. (DG)

  13. Nuclear data and related services

    International Nuclear Information System (INIS)

    Tuli, J.K.

    1985-01-01

    National Nuclear Data Center (NNDC) maintains a number of data bases containing bibliographic information and evaluated as well as experimental nuclear properties. An evaluated computer file maintained by the NNDC, called the Evaluated Nuclear Structure Data File (ENSDF), contains nuclear structure information for all known nuclides. The ENSDF is the source for the journal Nuclear Data Sheets which is produced and edited by NNDC. The Evaluated Nuclear Data File (ENDF), on the other hand is designed for storage and retrieval of such evaluated nuclear data as are used in neutronic, photonic, and decay heat calculations in a large variety of applications. The NNDC maintains three bibliographic files: NSR - for nuclear structure and decay data related references, CINDA - a bibliographic file for neutron induced reactions, and CPBIB - for charged particle reactions. Selected retrievals from evaluated data and bibliographic files are possible on-line or on request from NNDC

  14. Building and maintaining media contacts

    International Nuclear Information System (INIS)

    Fenton, Bob

    2000-01-01

    This presentation is answering the question: 'how does British Energy build and maintain its relationships with journalists in so many areas', not only the basic industrial correspondents that you would expect to have to deal with an industry British Energy, but those dealing with science and technology, the environment, personnel and training, city and financial, political, and on and on, and that is just the national press. Then add the local and regional media around power station sites - literally hundreds of contacts and you start to get an idea about the size of our media contact database. But it is managed it rather well. Every six months British Energy takes part in a survey run by one of the UK's leading market research companies who conducts a poll among journalists and then rate each company's performance. In the last three years British Energy has not been outside the top five in most categories, and in the top two in several. The answer is a lot of work over a long period of time. You cannot expect to build trusting relationships with a journalist overnight. At British Energy the key is being open and honest, and always available. Of course good media relations is not a one-way street, and there has to be some element of compromise if you are to achieve a relationship based on mutual trust

  15. Biodegradation of radioactive organic liquid waste from spent fuel reprocessing; Biodegradacao de rejeitos radioativos liquidos organicos provenientes do reprocessamento do combustivel nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Rafael Vicente de Padua

    2008-07-01

    The research and development program in reprocessing of low burn-up spent fuel elements began in Brazil in 70's, originating the lab-scale hot cell, known as Celeste located at Nuclear and Energy Research Institute, IPEN - CNEN/SP. The program was ended at the beginning of 90's, and the laboratory was closed down. Part of the radioactive waste generated mainly from the analytical laboratories is stored waiting for treatment at the Waste Management Laboratory, and it is constituted by mixture of aqueous and organic phases. The most widely used technique for the treatment of radioactive liquid wastes is the solidification in cement matrix, due to the low processing costs and compatibility with a wide variety of wastes. However, organics are generally incompatible with cement, interfering with the hydration and setting processes, and requiring pre -treatment with special additives to stabilize or destroy them. The objective of this work can be divided in three parts: organic compounds characterization in the radioactive liquid waste; the occurrence of bacterial consortia from Pocos de Caldas uranium mine soil and Sao Sebastiao estuary sediments that are able to degrade organic compounds; and the development of a methodology to biodegrade organic compounds from the radioactive liquid waste aiming the cementation. From the characterization analysis, TBP and ethyl acetate were chosen to be degraded. The results showed that selected bacterial consortia were efficient for the organic liquid wastes degradation. At the end of the experiments the biodegradation level were 66% for ethyl acetate and 70% for the TBP. (author)

  16. Organic tritium in freshwater ecosystems: long-term trends in the environment of French nuclear power plants

    International Nuclear Information System (INIS)

    Gontier, G.; Siclet, F.

    2011-01-01

    From 1977 to 2009, more than 600 measurements of organic tritium were performed on fish, aquatic plants and sediments upstream and downstream of the 15 French NPP located along rivers. Examination of the results shows that organic tritium activities have exponentially decreased over the last thirty years, in all components of aquatic ecosystems. Upstream of all NPP, OBT levels in sediments are higher than in plants and fish, themselves larger than HTO in surface water. The magnitude of these differences and the long-term trends depend on the river basin and can be explained by the varying nature of tritium sources. In river catchment, where atmospheric test fallout is the main source of tritium, the observed levels result from the exposure of aquatic organisms to two distinct tritium pools of different ages: atmospheric tritiated water (representing present fallout), and organic tritium from soils (formed over several decades) which supplies particulate matter to surface waters. In the Rhone and Rhine river basins, an additional source of organic tritium of very low bio-availability, probably originating from the luminescent paint industry, is responsible for the spiking of sediment organic matter up to 100 to 100 000 Bq.L -1 combustion water. The comparison of upstream and downstream NPP tritium levels shows that the influence of tritium discharges is detectable only in rivers, with low background OBT activities, i.e in basins other than the Rhone and Rhine. The observed increase in plant and fish OBT is lower than the added HTO activity in water due to discharge, which supports the absence of bioaccumulation for tritium originating from HTO and the absence of highly bio-available tritiated organic molecules in NPP discharges. (authors)

  17. Building and Maintaining Healthy Organizations: The Key to Future Success

    Science.gov (United States)

    2000-10-01

    A diamond mine manned by brutalized slave labor or an inhumane sweatshop that manufactures dresses using child workers may be “successful,” but...recall such publicized issues as global warming, sweatshop labor, rain forest destruction), special-interest activism, and rising popular expectations

  18. Nuclear imaging

    International Nuclear Information System (INIS)

    Miller, J.H.; Reid, B.S.

    1985-01-01

    Nuclear imaging, utilizing relatively low photon energy emitting isotopes, allows an assessment of anatomic configuration and organ function. This method of imaging is predicted on the utilization of physiologically active radioisotope-labeled compounds or biologically active radioisotopes. Localization of such isotopes in normal or abnormal concentrations may be due to varying physiological or pathological mechanisms

  19. Use of self-organizing maps for classification of defects in the tubes from the steam generator of nuclear power plants; Classificacao de defeitos em tubos de gerador de vapor de plantas nucleares utilizando mapas auto-organizaveis

    Energy Technology Data Exchange (ETDEWEB)

    Mesquita, Roberto Navarro de

    2002-07-01

    This thesis obtains a new classification method for different steam generator tube defects in nuclear power plants using Eddy Current Test signals. The method uses self-organizing maps to compare different signal characteristics efficiency to identify and classify these defects. A multiple inference system is proposed which composes the different extracted characteristic trained maps classification to infer the final defect type. The feature extraction methods used are the Wavelet zero-crossings representation, the linear predictive coding (LPC), and other basic signal representations on time like module and phase. Many characteristic vectors are obtained with combinations of these extracted characteristics. These vectors are tested to classify the defects and the best ones are applied to the multiple inference system. A systematic study of pre-processing, calibration and analysis methods for the steam generator tube defect signals in nuclear power plants is done. The method efficiency is demonstrated and characteristic maps with the main prototypes are obtained for each steam generator tube defect type. (author)

  20. Quality control in nuclear medicine. Addendum to 'Quality assurance in nuclear medicine', World Health Organization, 1982. Following a training workshop in Neuherberg, Munich, Federal Republic of Germany, November 23-30, 1983

    International Nuclear Information System (INIS)

    Cradduck, T.D.; Busemann Sokole, E.

    2006-01-01

    Based on the results of a workshop, sponsored by the German Federal Ministry of the Interior (BMI) and the World Health Organization (WHO), held in Neuherberg, Munich, 1983, a revised concept of quality control (QC) in nuclear medicine is proposed. In a previous document published by the WHO in 1982, a set of rigorous daily, weekly, monthly, quarterly and half-quarterly QC protocols was recommended. The revised concept suggested by the 1983 workshop participants is that of a simple, total system, QC test that can be applied on a frequent, probably daily, basis. Any deviation of the results of such a test from the accepted norm will require further investigation and decision trees can then be applied to localize faults

  1. Knowledge Management (KM) Risk Assessment of Critical Knowledge Loss in an Organization with Expanding Nuclear Power Program

    International Nuclear Information System (INIS)

    Mohsin, M.

    2014-01-01

    Risk and KM risk assessment of critical knowledge loss: • Risk is defined in the Project Management Body of Knowledge (PMBOK,2004) as an event or unclear situation that will influence the timing, cost and quality of a project. • This study considers attrition due to retirements of its workforce -- A risk for the organization as it has implications of loss of knowledge for the organization and thereby on its quality and output. • This study assesses the magnitude of the anticipated Risk of Knowledge Loss in three Operational NPPs namely CNPGS (C-1 and C-2) and K-1 based on the factor of Time until Retirement

  2. Advanced remotely maintainable force-reflecting servomanipulator concept

    International Nuclear Information System (INIS)

    Kuban, D.P.; Martin, H.L.

    1984-01-01

    A remotely maintainable force-reflecting servomanipulator concept is being developed at the Oak Ridge National Laboratory as part of the Consolidated Fuel Reprocessing Program. This new manipulator addresses requirements of advanced nuclear fuel reprocessing with emphasis on force reflection, remote maintainability, reliability, radiation tolerance, and corrosion resistance. The advanced servomanipulator is uniquely subdivided into remotely replaceable modules which will permit in situ manipulator repair by spare module replacement. Manipulator modularization and increased reliability are accomplished through a force transmission system that uses gears and torque tubes. Digital control algorithms and mechanical precision are used to offset the increased backlash, friction, and inertia resulting from the gear drives. This results in the first remotely maintainable force-reflecting servomanipulator in the world. 10 references, 4 figures, 1 table

  3. The role of customs services and World Customs Organization (WCO)'s enforcement programme to combat nuclear and other radioactive materials smuggling

    International Nuclear Information System (INIS)

    Saka, E.

    1999-01-01

    The World Customs Organization (established as the Customs Co-operation Council in 1952) is an independent inter-governmental body with world-wide membership (150) whose enforcement mission could be summarized as 'to assist its Members in strengthening their enforcement measures through training and technical programmes designed to combat Customs offences', which also include nuclear and other radioactive materials smuggling. One of the best strategies for an effective fight against illicit trafficking in nuclear and other radioactive materials is to stop their illegal movement at the national border before entering or leaving the country. From this point, Customs services are unique governmental cross-border control agencies, which are mostly located at national cross-border checking points. In addition to this local advantage, Customs expertise and authority in checking documents, goods, vehicles and passengers deserve special mentioning. It should also be noted that Customs services have great experience on how to combat and respond to transnational crime and criminals. On the other hand, in order to maximize on their experience, they should be furnished with sufficient authority for investigation, detection equipment and supported through relevant training programmes. In line with the request made by Member States, the World Customs Organization (WCO) Secretariat has recently developed an enforcement programme on combating nuclear and other radioactive materials smuggling. This programme is based on awareness raising, development of training materials, designing training programmes, promoting exchange of information and improving co-operation at all levels. The WCO Database, the WCO Regional Intelligence Liaison (RILO) project and WCO bilateral and multilateral co-operative initiatives are three key tools which enable Customs administrations to develop accurate, timely and rapid exchange of information and intelligence. Within the concept of international co

  4. Knowledge management: Preserving skills and expertise for nuclear industry

    International Nuclear Information System (INIS)

    Urjan, Daniel; Havris, Alexandru

    2003-01-01

    All healthy organizations generate and use knowledge. As organizations interact with their environments, they absorb information, turn it into knowledge and take action based on it in combination with their experiences, values and internal rules. Without knowledge, an organization could not organize itself; it would be unable to maintain itself as a functioning enterprise. Like any highly technical endeavor, the use of nuclear technology relies heavily on a vast accumulation of knowledge - volumes of scientific research, engineering analysis, operational data, regulatory reviews and many other types of technical information - combined with a complex assortment of people with the requisite educational background, expertise and acquired insight to apply that body of knowledge safely and effectively. Methods must be found to better capture this enormous body of nuclear experience. Today's nuclear workforce needs to document knowledge and then mentor the new nuclear scientists to build upon it, rather than having to re-create it. The latest studies have shown that at present NPPs cannot be replaced by other kinds of electric sources and in no case by renewable ones in an efficient manner. Therefore it is necessary to carefully manage knowledge gathered in the nuclear field during the years and to keep on the nuclear safety research, education and training to ensure and upgrade safe and reliable operation of existing and future nuclear facilities. Having in mind the complexity of this issue of global concern, this presentation tries to provide a brief overview of what knowledge management is and how it can help organizations to preserve knowledge, skills and expertise, particularly for the nuclear environment. What are the challenges of nuclear knowledge management and who should lead knowledge management efforts are also some of the issues covered in the presentation. (authors)

  5. Nuclear information services at the National Nuclear Data Center

    International Nuclear Information System (INIS)

    Burrows, T.W.; Tuli, J.K.

    1997-01-01

    The National Nuclear Data Center (NNDC) at the Brookhaven National Laboratory has maintained and disseminated data from several numeric and bibliographic data bases for many years. These data bases now cover most of low- and medium-energy nuclear physics and are produced by the NNDC and other groups belonging to various international and national networks. The numeric and bibliographic nuclear data bases maintained by the National Nuclear Data Center and access to these data bases is described. The U.S. Nuclear Data and Reaction Data Networks is also briefly described. (author)

  6. Nuclear law - Nuclear safety

    International Nuclear Information System (INIS)

    Pontier, Jean-Marie; Roux, Emmanuel; Leger, Marc; Deguergue, Maryse; Vallar, Christian; Pissaloux, Jean-Luc; Bernie-Boissard, Catherine; Thireau, Veronique; Takahashi, Nobuyuki; Spencer, Mary; Zhang, Li; Park, Kyun Sung; Artus, J.C.

    2012-01-01

    This book contains the contributions presented during a one-day seminar. The authors propose a framework for a legal approach to nuclear safety, a discussion of the 2009/71/EURATOM directive which establishes a European framework for nuclear safety in nuclear installations, a comment on nuclear safety and environmental governance, a discussion of the relationship between citizenship and nuclear, some thoughts about the Nuclear Safety Authority, an overview of the situation regarding the safety in nuclear waste burying, a comment on the Nome law with respect to electricity price and nuclear safety, a comment on the legal consequences of the Fukushima accident on nuclear safety in the Japanese law, a presentation of the USA nuclear regulation, an overview of nuclear safety in China, and a discussion of nuclear safety in the medical sector

  7. McClellan Nuclear Radiation Center (MNRC) TRIGA reactor: The national organization of test research and training reactors

    International Nuclear Information System (INIS)

    Kiger, Kevin M.

    1994-01-01

    This year's TRTR conference is being hosted by the McClellan Nuclear Radiation Center. The conference will be held at the Red Lion Hotel in Sacramento, CA. The conference dates are scheduled for October 11-14, 1994. Deadlines for sponsorship commitment and papers have not been set, but are forthcoming. The newly remodeled Red Lion Hotel provides up-to-date conference facilities and one of the most desirable locations for dining, shopping and entertainment in the Sacramento area. While attendees are busy with the conference activities, a spouses program will be available. Although the agenda has not been set, the Sacramento area offers outings to San Francisco, Pier 39, Ghirardelli Square (famous for their chocolate), and a chance to discover 'El Dorado' in the gold country. Not to forget our own bit of history with visits to 'Old Sacramento and Old Folsom', where antiquities abound, to the world renown train museum and incredible eating establishments. (author)

  8. Reactivity of nitrate and organic acids at the concrete–bitumen interface of a nuclear waste repository cell

    International Nuclear Information System (INIS)

    Bertron, A.; Jacquemet, N.; Erable, B.; Sablayrolles, C.; Escadeillas, G.; Albrecht, A.

    2014-01-01

    Highlights: • Interactions of cement paste and organic acid–nitrate solutions were investigated. • Cement leaching imposed alkaline pH (>10) very rapidly in the liquid media. • Acetic acid action on cement paste was similar to that of classical leaching. • Oxalic acid attack formed Ca-oxalate salts; organic matter in solution decreased. • Nitrate was stable under abiotic conditions and with organic matter. - Abstract: This study investigates the fate of nitrate and organic acids at the bitumen–concrete interface within repository cell for long-lived, intermediate-level, radioactive wastes. The interface was simulated by a multiphase system in which cementitious matrices (CEM V cement paste specimens) were exposed to bitumen model leachates consisting of nitrates and acetic acid with and without oxalic acid, chemical compounds likely to be released by bitumen. Leaching experiments were conducted with daily renewal of the solutions in order to accelerate reactions. The concentrations of anions (acetate, oxalate, nitrate, and nitrite) and cations (calcium, potassium) and the pH were monitored over time. Mineralogical changes of the cementitious matrices were analysed by XRD. The results confirmed the stability of nitrates in the abiotic conditions of the experiments. The action of acetic acid on the cementitious matrix was similar to that of ordinary leaching in the absence of organic acids (i.e. carried out with water or strong acids); no specific interaction was detected between acetate and cementitious cations. The reaction of oxalic acid with the cementitious phases led to the precipitation of calcium oxalate salts in the outer layer of the matrix. The concentration of oxalate was reduced by 65% inside the leaching medium

  9. Building and maintaining media relations

    International Nuclear Information System (INIS)

    Oesterberg, Anders

    2000-01-01

    Full text: In my opinion good media relations are among the most valuable investments regarding the communications and Public Relations operations within an Organisation. This means, that all the work you put up in building and maintaining media relations, is worth all the efforts. It can mean the difference between success or failure. Although a reporter never would admit that he or she is easily influenced, the fact is that you would get better press in an emergency case if you have a positive personal relation to the reporter. So, in my opinion there is nothing more important, in building and maintaining media relations, than the face-to-face-contact. My experience of good personal relations to reporters is also that you're not only getting better press in emergency cases. You are more successful in getting published when you have something positive to say, too. Honesty and openness are two key-words in this context. I have never tried to manipulate and delude a reporter, since that definitely would ruin the relationship. I always try to be as straight forward as possible and underline what I can say and what I can't. That instead of presenting some forced lies. For me, it is also very important to create some kind of mid-field ground, where the reporter and I can meet unprejudiced. Sense of humour and distance, both to yourself and your organisation, are two main characteristics that are invaluable in order to create a good personal relationship with a reporter. But, I'm very accurate in emphasizing when I enter my role as a company representative. All in order to be regarded as correct, yet obliging. To be quick when it comes to returning calls is another vital component that gives the reporter a feeling that he or she is important enough to be contacted as soon as possible. This service-minded attitude is of course good for the relationship. Besides the more personal relation it's important to have a business-like relation, where you show a great deal of

  10. Nuclear law in progress

    International Nuclear Information System (INIS)

    Manóvil, Rafael Mariano

    2014-01-01

    The 21. AIDN / INLA Congress was organized by the International Nuclear Law Association, in Buenos Aires, between the October 20 and 23, 2014. In this event, were presented almost 50 papers about these subjects: radioactive sources, safety and licensing, radioactive waste management, radiation protection, nuclear transport, security and non-proliferation, nuclear liability and insurance, etc.

  11. Spanish nuclear industry

    International Nuclear Information System (INIS)

    1994-01-01

    In this book published to commemorate the twentieth anniversary of the Spanish Nuclear Society, it is included a report on the Spanish Nuclear Industry. The Spanish Companies and Organizations in nuclear world are: CIEMAT, Empresarios Agrupados, ENRESA, ENUSA, ENDESA, Grupo Iberdrola, LAINSA, INITEC AND TECNATOM. Activities, history and research programs of each of them are included

  12. Wireless amplified nuclear MR detector (WAND) for high-spatial-resolution MR imaging of internal organs: preclinical demonstration in a rodent model.

    Science.gov (United States)

    Qian, Chunqi; Yu, Xin; Chen, Der-Yow; Dodd, Stephen; Bouraoud, Nadia; Pothayee, Nikorn; Chen, Yun; Beeman, Scott; Bennett, Kevin; Murphy-Boesch, Joseph; Koretsky, Alan

    2013-07-01

    To assess the feasibility of imaging deep-lying internal organs at high spatial resolution by imaging kidney glomeruli in a rodent model with use of a newly developed, wireless amplified nuclear magnetic resonance (MR) detector. This study was approved by the Animal Care and Use Committee at the National Institutes of Health/National Institute of Neurologic Disorder and Stroke. As a preclinical demonstration of this new detection technology, five different millimeter-scale wireless amplified nuclear MR detectors configured as double frequency resonators were chronically implanted on the medial surface of the kidney in five Sprague-Dawley rats for MR imaging at 11.7 T. Among these rats, two were administered gadopentetate dimeglumine to visualize renal tubules on T1-weighted gradient-refocused echo (GRE) images, two were administered cationized ferritin to visualize glomeruli on T2*-weighted GRE images, and the remaining rat was administered both gadopentetate dimeglumine and cationized ferritin to visualize the interleaved pattern of renal tubules and glomeruli. The image intensity in each pixel was compared with the local tissue signal intensity average to identify regions of hyper- or hypointensity. T1-weighted images with 70-μm in-plane resolution and 200-μm section thickness were obtained within 3.2 minutes to image renal tubules, and T2*-weighted images of the same resolution were obtained within 5.8 minutes to image the glomeruli. Hyperintensity from gadopentetate dimeglumine enabled visualization of renal tubules, and hypointensity from cationic ferritin enabled visualization of the glomeruli. High-spatial-resolution images have been obtained to observe kidney microstructures in vivo with a wireless amplified nuclear MR detector.

  13. Guidelines and workbook for assessment of organization and administration of utilities seeking operating license for a nuclear power plant. Guidelines for utility organization and administration plan. Volume 1, Revision 1

    International Nuclear Information System (INIS)

    Thurber, J.A.; Olson, J.; Osborn, R.N.; Sommers, P.; Widrig, R.D.

    1986-09-01

    Volumes 1 and 2 of this report are a partial response to the requirements of Item I.B.1.1 of the ''NRC Action Plan Developed as a Result of the TMI-2 Accident,'' NUREG-0660, and are designed to serve as a basis for replacing the earlier NUREG-0731, ''Guidelines for Utility Management Structure and Technical Resources.'' These Guidelines are intended to provide guidance to the user in preparing a written plan for a proposed nuclear organization and administration. The purpose of the Workbook (Vol. 2) is to guide the NRC reviewer through a systematic review and assessment of a proposed organization and administration. It is the NRC's intention to incorporate these Guidelines and Workbook into a future revision of the Standard Review Plan (SRP), NUREG-0800. However, at this time the report is being published so that the material may be used on a voluntary basis by industry to systematically prepare or evaluate their organization or administration plans. Use of the report by the NRC would not occur until after it has been incorpoarted in the SRP

  14. Guidelines and workbook for of organization and administration of utilities seeking operating license for a nuclear power plant. Workbook for assessment of organization and management. Volume, 2, Revision 1

    International Nuclear Information System (INIS)

    Thurber, J.A.; Olson, J.; Osborn, R.N.; Sommers, P.; Widrig, R.D.

    1986-09-01

    This report is a partial response to the requirements of Item I.B.1.1 of the ''NRC Action Plan Developed as a Result of the TMI-2 Accident,'' NUREG-0660, and is designed to serve as a basis for replacing the earlier NUREG-0731, ''Guidelines for Utility Management Structure and Technical Resources.'' The Guidelines are intended to provide guidance to the user in preparing a written plan for a proposed nuclear organization and administration. The purpose of the Workbook is to guide the NRC reviewer through a systematic review and assessment of a proposed organization and administration. It is the NRC's intention to incorporate these Guidelines and Workbook into a future revision of the Standard Review Plan (SRP), NUREG-0800. However, at this time the report is being published so that the material may be used on a voluntary basis by industry to systematically prepare or evaluate their organization or administration plans. Use of the report by the NRC would not occur until after it has been incorporated in the SRP

  15. Nuclear and radiation safety policy

    International Nuclear Information System (INIS)

    Mikus, T; Strycek, E.

    1998-01-01

    Slovenske elektrarne (SE) is a producer of electricity and heat, including from nuclear fuel source. The board of SE is ultimately responsible for nuclear and radiation safety matters. In this leaflet main principles of maintaining nuclear and radiation safety of the Company SE are explained

  16. Basic research for nuclear energy : a study on photo-catalytic decomposition reactions of organics dissolved in water

    International Nuclear Information System (INIS)

    Sung, K. W.; Na, J. W.; Cho, Y. H.; Kim, K. R.

    1999-01-01

    In an experiment on TiO 2 photo-catalysis of five nitrogen-containing organic compounds, the changes of pH and total carbon contents were measured, and the dependence of their photo-catalytic characteristic upon their chemical structures were investigated. -- calculation of the effect of ionic carbon species in an aqueous solution on thermodynamic equilibrium, pH and conductivity showed a small quantity of organics could lead conductivity increase and pH reduction. -- Based on the results of photo-catalytic experiment of ethylamine, phenylhydrazine, pyridine, urea or EDTA, irradiated for 180 minutes after adsorption onto titanium dioxide for 60 minutes, relationship between nitrogen atomic charge and the first-order rate constant was as the following: R (1st - order rate constant) = δ (ε - a ) 1/3 + b where, ε : atomic charge of nitrogen in a molecular, δ, a and b : corrective coefficients

  17. Basic research for nuclear energy : a study on photo-catalytic decomposition reactions of organics dissolved in water

    Energy Technology Data Exchange (ETDEWEB)

    Sung, K. W.; Na, J. W.; Cho, Y. H.; Kim, K. R

    1999-01-01

    In an experiment on TiO{sub 2} photo-catalysis of five nitrogen-containing organic compounds, the changes of pH and total carbon contents were measured, and the dependence of their photo-catalytic characteristic upon their chemical structures were investigated. -- calculation of the effect of ionic carbon species in an aqueous solution on thermodynamic equilibrium, pH and conductivity showed a small quantity of organics could lead conductivity increase and pH reduction. -- Based on the results of photo-catalytic experiment of ethylamine, phenylhydrazine, pyridine, urea or EDTA, irradiated for 180 minutes after adsorption onto titanium dioxide for 60 minutes, relationship between nitrogen atomic charge and the first-order rate constant was as the following: R (1st - order rate constant) = {delta} ({epsilon} - a ){sup 1/3} + b where, {epsilon} : atomic charge of nitrogen in a molecular, {delta}, a and b : corrective coefficients.

  18. Use of self-organizing maps for classification of defects in the tubes from the steam generator of nuclear power plants

    International Nuclear Information System (INIS)

    Mesquita, Roberto Navarro de

    2002-01-01

    This thesis obtains a new classification method for different steam generator tube defects in nuclear power plants using Eddy Current Test signals. The method uses self-organizing maps to compare different signal characteristics efficiency to identify and classify these defects. A multiple inference system is proposed which composes the different extracted characteristic trained maps classification to infer the final defect type. The feature extraction methods used are the Wavelet zero-crossings representation, the linear predictive coding (LPC), and other basic signal representations on time like module and phase. Many characteristic vectors are obtained with combinations of these extracted characteristics. These vectors are tested to classify the defects and the best ones are applied to the multiple inference system. A systematic study of pre-processing, calibration and analysis methods for the steam generator tube defect signals in nuclear power plants is done. The method efficiency is demonstrated and characteristic maps with the main prototypes are obtained for each steam generator tube defect type. (author)

  19. Self-organizing maps of Kohonen (SOM) applied to multidimensional monitoring data of the IEA-R1 nuclear research reactor

    International Nuclear Information System (INIS)

    Affonso, Gustavo S.; Pereira, Iraci M.; Mesquita, Roberto N. de; Bueno, Elaine I.

    2011-01-01

    Multivariate statistics comprise a set of statistical methods used in situations where many variables are database space subsets. Initially applied to human, social and biological sciences, these methods are being applied to many other areas such as education, geology, chemistry, physics, engineering, and many others. This spectra expansion was possible due to recent technological development of computation hardware and software that allows high and complex databases to be treated iteratively enabling further analysis. Following this trend, the neural networks called Self-Organizing Maps are turning into a powerful tool on visualization of implicit and unknown correlations in big sized database sets. Originally created by Kohonen in 1981, it was applied to speech recognition tasks. The SOM is being used as a comparative parameter to evaluate the performance of new multidimensional analysis methodologies. Most of methods require good variable input selection criteria and SOM has contributed to clustering, classification and prediction of multidimensional engineering process variables. This work proposes a method of applying SOM to a set of 58 IEA-R1 operational variables at IPEN research reactor which are monitored by a Data Acquisition System (DAS). This data set includes variables as temperature, flow mass rate, coolant level, nuclear radiation, nuclear power and control bars position. DAS enables the creation and storage of historical data which are used to contribute to Failure Detection and Monitoring System development. Results show good agreement with previous studies using other methods as GMDH and other predictive methods. (author)

  20. Sample loading for C-14 measurement in the simulated organic solvent waste from a CANDU Nuclear Power Plant

    International Nuclear Information System (INIS)

    Dianu, Magdalena; Dobrin, Relu; Podina, Corneliu

    2005-01-01

    The paper evaluates the performance of two commercially available liquid scintillation cocktails designed for counting nonaqueous (organic) samples. To choose a suitable scintillation cocktail is not always easy because many cocktails are available on the market. The efficiency, sample loading, sample type are all important variables that help determine the suitability of a liquid scintillation cocktail for C-14 measurement. Samples were counted in a 2100 TRI-CARB Packard Model liquid scintillation analyzer. (authors)