WorldWideScience

Sample records for nowe detektory scyntylacyjne

  1. LSD Now: 1973

    Science.gov (United States)

    Chunko, John A.

    1973-01-01

    LSD NOW is a nationwide, statistical survey and analysis of hallucinogenic drug use by individuals presently in formal educational surroundings. Analysis, concentrating on the extent and rationale related to the use of such drugs, now offers a deeper and more meaningful understanding of a particular facet of the drug culture. This understanding…

  2. Here and now

    OpenAIRE

    Dean, J.

    2015-01-01

    'Here and Now' is an album of nine original jazz based compositions (64 mins total). \\ud \\ud 'Here and Now' was released on Pathway Records and was recommended by itunes as 'Music you must hear' in the jazz section (October - December 2016).\\ud \\ud Further research from the recorded output involves developing an analysis of the use of muscle memory in guitar improvisation, taken from transcriptions of the improvisations in both studio and live settings\\ud \\ud The album features James Dean (gu...

  3. ServiceNow

    Data.gov (United States)

    US Agency for International Development — A cloud based service for creating a single system of record for all types of business services used by OCIO. Service Now applications are built on a single platform...

  4. The future is now

    Directory of Open Access Journals (Sweden)

    Craig L Johnstone

    2008-10-01

    Full Text Available Our generation has failed to live up to its obligations to prevent climate change and any steps we take now, however welcome, will not totally reverse the trends. We need urgently to prepare now for the human consequences of climate change.

  5. Modification Semantics in Now-Relative Databases

    DEFF Research Database (Denmark)

    Torp, Kristian; Jensen, Christian Søndergaard; Snodgrass, R. T.

    2004-01-01

    Most real-world databases record time-varying information. In such databases, the notion of ??the current time,?? or NOW, occurs naturally and prominently. For example, when capturing the past states of a relation using begin and end time columns, tuples that are part of the current state have some...... past time as their begin time and NOW as their end time. While the semantics of such variable databases has been described in detail and is well understood, the modification of variable databases remains unexplored. This paper defines the semantics of modifications involving the variable NOW. More...... specifically,  the problems with modifications in the presence of NOW are explored, illustrating that the main problems are with modifications of tuples that reach into the future. The paper defines the semantics of modifications?including insertions, deletions, and updates?of databases without NOW, with NOW...

  6. Live your questions now

    OpenAIRE

    Brownrigg, Jenny

    2016-01-01

    'Live Your Questions Now' is a case study for Cubitt Education's publication 'Aging in Public: creative practice in ageing and the public realm from across the UK', edited by Daniel Baker and published by Cubitt Gallery, Studios and Education, London in 2016. The publication was linked to Cubitt's programme 'Public Wisdom' (2011-2015). My case study is about 'Live your questions now', a group exhibition I curated in 2011 for Mackintosh Museum, The Glasgow School of Art. 'Live your questions n...

  7. "Stop Diabetes Now!"

    Science.gov (United States)

    ... of this page please turn Javascript on. Feature: Diabetes "Stop Diabetes Now!" Past Issues / Fall 2009 Table of Contents ... Tips for Seniors at Risk for Type 2 Diabetes Lifestyle changes that lead to weight loss—such ...

  8. Mastering ServiceNow

    CERN Document Server

    Wood, Martin

    2015-01-01

    This book is intended for those who are familiar with web technologies such as JavaScript. We start from the computing fundamentals to understand how ServiceNow is architected, working from the ground up to really leverage the full capabilities of the platform.

  9. Scientific publications: now a marketing decision?

    Science.gov (United States)

    Scientists have been publishing in journals related to their disciplines. Now with the advent of the internet, many more options are now available and scientific publication has become a marketing decision. Scientific journals are rated by "impact factor" which is based on the average number of cita...

  10. Where We Now Stand

    Science.gov (United States)

    Lumsden, Keith G.

    1969-01-01

    Noting the acceleration of scientific evaluation, the author focuses his attention on where we now stand in the evaluation of two methods of instruction: programed learning materials and television. (Editor)

  11. Silicon-lithium nuclear radiation detectors. Kremnii-litievye detektory yadernogo izlucheniya

    Energy Technology Data Exchange (ETDEWEB)

    Azimov, S.A.; Muminov, R.A.; Shamirzaev, S.Kh.; Yafasov, A.Ya.

    1981-01-01

    A presentation is made of the physical principles underlying the design, building, and technology of silicon-lithium detectors and ways of improving them. Criteria of nuclear radiation control and selection and the connection between radiation and detector properties are discussed. A study is made of the effect that various defects have on the process of charge collection and formation of amplitude spectra during the recording of various types of particles. A detailed examination is made of the optimal technological systems for making detectors with high energy and time resolutions, and features of producing high-quality detectors which employ the use of ion-laser and other methods of modern semiconductor technology. 322 references, 102 figures, 2 tables.

  12. ServiceNow as a platform – practical research

    OpenAIRE

    Nechyporenko, Tamara

    2015-01-01

    In this thesis I am going to cover the main aspects of ServiceNow platform, what is it, and related areas to ServiceNow technologies such as cloud service technologies and ITIL framework, how it is used in ServiceNow. All the definitions and descriptions will be in details and a reader can get the important terms and definitions. The main scope of the thesis is practical research and creation of portal based on that research. The portal will be implemented using ServiceNow platform, Servic...

  13. Now entering phase two...

    CERN Multimedia

    Katarina Anthony

    2012-01-01

    Building on the success of their feasibility phase, the CLIC test facility, CTF3, has just launched into a five-year project development phase. This will involve detailed performance optimisation studies, marking the project’s transition from pure research and development to prototyping and construction.   CLIC accelerator modules under construction at CERN. “With the feasibility phase now complete, we have established that CLIC can be built,” says Roberto Corsini, CLIC Collaboration spokesperson. “Now we want to be sure that it can provide the luminosity and energy performance needed. We will be looking at the engineering, performance and cost of a real CLIC machine also seeing if we can reduce it.” CTF3’s second phase will focus on selected performance-related research areas for further investigation. The largest of these involves the construction and testing of several authentic CLIC accelerator modules that are currently being ...

  14. Neu/Now tuleb varsti

    Index Scriptorium Estoniae

    2011-01-01

    Neu/Now festivalil saab 17.-20. novembril Tallinna vanalinnas näha 35 kunstiprojekti 17 riigist. Cian McKenna (Iirimaa) disainiprojektist "Digitaalne teraapia", Richard Schwarzi (Austria) visuaalse kunsti projektist "Pikslitest" ja Maartje Meijeri (Holland) muusikaprojektist "Kuidas kirjutada fuugat?", mida tõstsid esile festivali kunstilised juhid Anthony Dean ja Paula Crabtree

  15. Preparedness Now! An Emergency Survival Guide

    CERN Document Server

    Edwards, Aton

    2009-01-01

    In uncertain times, a solid preparedness plan is essential for every individual and family. PREPAREDNESS NOW! navigates the new realities of twenty-first century living: extreme weather, economic instability, terror attacks, and more. Packed with checklists, resources, and step-by-step instructions, PREPAREDNESS NOW! details everything needed for office, car, and home preparedness. This newly expanded and revised edition includes an extended chapter on food and water storage and urban gardening, techniques in personal defense, and the latest and best preparedness products on the market. This b

  16. Coping efficiently with now-relative medical data.

    Science.gov (United States)

    Stantic, Bela; Terenziani, Paolo; Sattar, Abdul

    2008-11-06

    In Medical Informatics, there is an increasing awareness that temporal information plays a crucial role, so that suitable database approaches are needed to store and support it. Specifically, most clinical data are intrinsically temporal, and a relevant part of them are now-relative (i.e., they are valid at the current time). Even if previous studies indicate that the treatment of now-relative data has a crucial impact on efficiency, current approaches have several limitations. In this paper we propose a novel approach, which is based on a new representation of now, and on query transformations. We also experimentally demonstrate that our approach outperforms its best competitors in the literature to the extent of a factor of more than ten, both in number of disk accesses and of CPU usage.

  17. Stop researching transformational leadership! Now!

    NARCIS (Netherlands)

    L.G. Tummers (Lars)

    2013-01-01

    markdownabstract__Intro__ Researchers all over the world, stop with your research on transformational leadership! Now! This could be the provocative conclusion after reading the recent article of Profs. Daan van Knippenberg and Sim Sitkin in The Academy of Management Annals (2013). These

  18. Particles, fields, and now strings

    International Nuclear Information System (INIS)

    Weinberg, S.

    1986-01-01

    The author traces the history of the struggle between two views of the world: a world of particles or a world of fields. These positions were crystallised as quantum field theory and S-matrix theory and now by the reintroduction of string theories. (Auth.)

  19. ATLAS: Now under new management

    CERN Multimedia

    Katarina Anthony

    2013-01-01

    On 1 March, the ATLAS Collaboration welcomed a new spokesperson, Dave Charlton (University of Birmingham), and two new deputy spokespersons, Thorsten Wengler (CERN) and Beate Heinemann (University of California, Berkeley and LBNL). The Bulletin takes a look at what’s in store for one of the world’s largest scientific collaborations.   ATLAS members at the 2010 collaboration meeting in Copenhagen. Image: Rune Johansen and Troels Petersen. ATLAS spokesperson Dave Charlton has seen the collaboration through countless milestones: from construction to start-up to the 4 July 2012 announcement, he’s been an integral part of the team. Now, after twelve years with the collaboration, Dave is moving into the main office for the next two years. “2012 was a landmark year for ATLAS,” says Dave. “We spent a lot of time in the limelight and, in many ways, all eyes are still on us. But with the shutdown now under way, our focus is ...

  20. And now, for the winners.

    CERN Multimedia

    Alizée Dauvergne

    2010-01-01

    The Computer Security Day held on 10 June was a success. There were eight presentations, with some forty people attending each session.     The presentation videos can be viewed on Indico. The computer security team’s new website is now up and running, with a wealth of useful information and advice. Go to http://cern.ch/Computer.Security.     The quiz attracted 130 participants, and the answers have now been posted on line! The quiz winners are: Lars Aprin, Richard Baud, Thibaut Bernard, Brice Copy, Daniele de Ruschi, Sébastien Gadrat, Amanda Garcia Munoz, Stephen Gowdy, Joni Hahkala, Joseph Izen, Ryszard Erazm Jurga, Jukka Klem, Danila Oleynik, Ian Pong, Pascal Serge Roguet, Jani Tapani Taskinen, Jan Therhaag, Yves Thurel, Adrian Vogel, Thomas White. Well done to all! If you haven’t done so already, you should soon be getting your prize (i.e. a book, a T-shirt or a bag, etc.).  

  1. Stop researching transformational leadership! Now!

    OpenAIRE

    Tummers, Lars

    2013-01-01

    markdownabstract__Intro__ Researchers all over the world, stop with your research on transformational leadership! Now! This could be the provocative conclusion after reading the recent article of Profs. Daan van Knippenberg and Sim Sitkin in The Academy of Management Annals (2013). These leadership professors write about the problems surrounding transformational leadership.

  2. Long-baseline experiments, now and soon!

    Indian Academy of Sciences (India)

    2012-11-01

    Nov 1, 2012 ... forward since the acceptance of the neutrino oscillation hypothesis following ... ations from this neutrino mixing 'Standard Model' yet. ... technology from ICARUS, which now has neutrino measurements at CERN Neutrinos to.

  3. Cancer Currents Now Available in Spanish

    Science.gov (United States)

    As part of our effort to more effectively reach patients, health care providers, and researchers with timely, authoritative, and scientifically accurate cancer information, we are now offering selected Cancer Currents blog posts in Spanish.

  4. PROFAM now self-supporting.

    Science.gov (United States)

    1984-01-01

    Mexico's 6-year contraceptive social marketing organization, known as PROFAM, has realized its goal of becoming self supporting. The organization now serves a much smaller consumer base than during its past subsidized years, yet it has been selling a mix of products to reach self sufficiency. According to Luis de la Macorra, the director, the organization established its own manufacturing plant and office, and the program's cost is now sustained by sales revenues. PROFAM's current cost per couple-years-protection (CYP) compares favorably with other programs. PROFAM rebounded from 2 devastating setbacks to expand its operations, while trimming its cost per CYP from $18.60 US in 1979 to $2.85 (exclusive of contraceptives) in 1983. Both setbacks occurred in 1981, when a change of political administration led to a government withdrawal of support, abrupt cessation of US Agency for International Development financial backing, and a cancellation of the program's permits to sell all products but condoms. Cancelled products included an oral contraceptive as well as foam and cream spermicides and a vaginal suppository. In 1984 PROFAM once again began social marketing sales of pills and injectables and selling spermicides and IUDs at regular prices. Additionally, the program has begun to branch out, expanding its family planning clinics to cover marginally urban locales and selling both a broad line of medical equipment and various consumer goods. Since its creation in 1978, PROFAM has substantially increased consumer awareness of contraceptives.

  5. Unschooling, Then and Now

    Directory of Open Access Journals (Sweden)

    Kellie ROLSTAD

    2013-12-01

    Full Text Available While the accountability and standardization movement continues to narrow curriculum in the US, unschooling families are redefining learning and recreating community in an atmosphere of love and trust. As professors of education and unschooling mothers, Rolstad and Kesson compare their unschooling experiences in two different eras, one in the early days of unschooling (1980s, and the other in the first decade of the 21st century. Kathleen Kesson was an unschooling pioneer when her children were unschooled in the early 1980s, and her children are now adults. She describes what it was like to unschool then, to do what she terms old school unschooling. Only a generation later, Kellie Rolstad began unschooling her three children, in a world transformed by the Internet and ease of access to both information and social networking, key components of unschooling today. Rolstad describes how her unschooling children connected play in real and virtual worlds, exploring ideas differently in many aspects from how Kessons children played and explored, and yet fundamentally and remarkably the same. In this article, Rolstad and Kesson share their experiences of trusting children, of giving them the space and the resources to learn and grow in the ways that are best for them, comparing along the way what it was like to unschool then and what it is like to unschool now, in this era when our society has come to distrust children more than ever.

  6. Geomorphology: now a more quantitative science

    International Nuclear Information System (INIS)

    Lal, D.

    1995-01-01

    Geomorphology, one of the oldest branches of planetary science, is now growing into a quantitative field with the development of a nuclear method capable of providing numeric time controls on a great variety of superficial processes. The method complement the conventional dating methods, e.g. 40 K/ 40 Ar, 87 Rb/ 87 Sr, by providing information on geomorphic processes., e.g. the dwell times of rocks on the earth's surface with strict geometrical constraints; e.g., rates of physical and chemical weathering in the past, chronology of events associated with glaciation, etc. This article attempts to discuss the new possibilities that now exist for studying a wide range of geomorphic processes, with examples of some specific isotopic changes that allow one to model glacial chronology, and evolutionary histories of alluvial fans and sand dunes. (author). 9 refs., 3 figs., 4 tabs

  7. Representing and querying now-relative relational medical data.

    Science.gov (United States)

    Anselma, Luca; Piovesan, Luca; Stantic, Bela; Terenziani, Paolo

    2018-03-01

    Temporal information plays a crucial role in medicine. Patients' clinical records are intrinsically temporal. Thus, in Medical Informatics there is an increasing need to store, support and query temporal data (particularly in relational databases), in order, for instance, to supplement decision-support systems. In this paper, we show that current approaches to relational data have remarkable limitations in the treatment of "now-relative" data (i.e., data holding true at the current time). This can severely compromise their applicability in general, and specifically in the medical context, where "now-relative" data are essential to assess the current status of the patients. We propose a theoretically grounded and application-independent relational approach to cope with now-relative data (which can be paired, e.g., with different decision support systems) overcoming such limitations. We propose a new temporal relational representation, which is the first relational model coping with the temporal indeterminacy intrinsic in now-relative data. We also propose new temporal algebraic operators to query them, supporting the distinction between possible and necessary time, and Allen's temporal relations between data. We exemplify the impact of our approach, and study the theoretical and computational properties of the new representation and algebra. Copyright © 2018 Elsevier B.V. All rights reserved.

  8. Neu/Now testib talenti kontekstis / Mart Niineste

    Index Scriptorium Estoniae

    Niineste, Mart, 1983-

    2011-01-01

    17.-20. novembrini toimuvast rahvusvahelisest kunstifestivalist Neu/Now. Kahetasandilise festivali raames toimuvast online-festivalist ja live-festivalist. Festivali Eesti poolne kuraator Marje Lohuaru

  9. Wartawan Media Now dalam Mengemas Berita: Perspektif Situational Theory

    Directory of Open Access Journals (Sweden)

    Dasrun Hidayat

    2015-07-01

    Full Text Available The study aims to map and describe relationships between concepts of activity of journalists in the media now cloning technology based activities and relationship between news reporters. This study discusses the focus of news coverage in media activities and relationships among the journalists in the era of technology. The theory used is situational theory Grunig and Hunt and descriptive method of Public Relations. The study found that the situation changes in the era of media encourage actions of unscrupulous hunters cloning news. News media such as online media should now be used as the initial data is not the primary data news writing. The presence of media now facilitates the work of journalists but not always produce good quality of news. Otherwise, the presence of technology encourages more active cloning news reporter. Media now can initiate active and apathetic public situations as influenced by quality news content. The presence of media technology changes the image of the relationship between journalists—from person to person or reporter to reporter to journalists with media technology.

  10. Now, It's Your Turn: How You Can Take Medicine Safely

    Science.gov (United States)

    ... turn Javascript on. Feature: Taking Medicines Safely Now, It's Your Turn: How You Can Take Medicine Safely ... medicine. The pharmacist has filled the prescription. Now it's up to you to take the medicine safely. ...

  11. Save Energy Now Assessments Results 2008 Detailed Report

    Energy Technology Data Exchange (ETDEWEB)

    Wright, Anthony L [ORNL; Martin, Michaela A [ORNL; Nimbalkar, Sachin U [ORNL; Quinn, James [U.S. Department of Energy; Glatt, Ms. Sandy [DOE Industrial Technologies Program; Orthwein, Mr. Bill [U.S. Department of Energy

    2010-09-01

    In October 2005, U.S. Department of Energy Secretary Bodman launched his Easy Ways to Save Energy campaign with a promise to provide energy assessments to 200 of the largest U.S. manufacturing plants. DOE's Industrial Technologies Program (ITP) responded to the Secretary's campaign with its Save Energy Now initiative, featuring a new and highly cost-effective form of energy savings assessment. The approach for these assessments drew heavily on the existing resources of ITP's technology delivery component. Over the years, ITP Technology Delivery has worked with industry partners to assemble a suite of respected software tools, proven assessment protocols, training curricula, certified energy experts, and strong partnerships for deployment. The Save Energy Now assessments conducted in calendar year 2006 focused on natural gas savings and targeted many of the nation's largest manufacturing plants - those that consume at least 1 TBtu of energy annually. The 2006 Save Energy Now assessments focused primarily on assessments of steam and process heating systems, which account for an estimated 74% of all natural gas use by U.S. manufacturing plants. Because of the success of the Save Energy Now assessments conducted in 2006 and 2007, the program was expanded and enhanced in two major ways in 2008: (1) a new goal was set to perform at least 260 assessments; and (2) the assessment focus was expanded to include pumping, compressed air, and fan systems in addition to steam and process heating. DOE ITP also has developed software tools to assess energy efficiency improvement opportunities in pumping, compressed air, and fan systems. The Save Energy Now assessments integrate a strong training component designed to teach industrial plant personnel how to use DOE's opportunity assessment software tools. This approach has the advantages of promoting strong buy-in of plant personnel for the assessment and its outcomes and preparing them better to

  12. Why work-life balance now?

    OpenAIRE

    Fleetwood, Steve

    2006-01-01

    In the vast literature on work-life balance one question remains seriously under-elaborated: Why now? The paper opens by recognising that flexible working practices can be employee friendly or employer friendly, and that current employer friendly practices tend to constrain, rather than enable, possibilities for work-life balance. Part two introduces neoliberalism, interpreting it as a new class strategy: the iron fist of a renewed ruling class offensive is wrapped in the velvet glove of free...

  13. Insure Kids Now (IKN) (Dental Care Providers)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Insure Kids Now (IKN) Dental Care Providers in Your State locator provides profile information for oral health providers participating in Medicaid and Children's...

  14. Brutally Unfair Tactics Totally OK Now

    DEFF Research Database (Denmark)

    Wilson, Douglas

    2011-01-01

    In this paper, I use a party game that I co-designed, Brutally Unfair Tactics Totally OK Now (B.U.T.T.O.N.), as a case study to suggest some alternative possibilities for the design of digitally-mediated play and games. Specifically, I argue that that intentionally “broken” or otherwise incomplet...

  15. The huge ATLAS cavern now fully excavated

    CERN Multimedia

    2002-01-01

    Excavation of the ATLAS cavern is now complete! At the end of two years' work involving a tremendous technical challenge, the civil engineering contractors have succeeded in digging out one of the biggest experimental caverns in the world. Bravo!

  16. Alanud on Neu/Now online-festival

    Index Scriptorium Estoniae

    2011-01-01

    4. okt.-l avatud Neu/Now festivali online-keskonnas esitletakse 23 riigi 135 noore kunstiprojekte. Nimetatud Eestist festivalile pääsenud 9 tööd. 17.-20. nov.-ni toimuval live-festivail esitletakse Tallinnas 17 riigi 35 kunstiprojekti (Eestist 5). Kandideerida said lõpetavad või äsja lõpetanud kunsti- ja muusikaerialade tudengid ELIA võrgustikku kuuluvatest ülikoolidest

  17. Nástroj pre podporu vývoja na platforme ServiceNow

    OpenAIRE

    Paulech, Matej

    2014-01-01

    The topic of this paper is creation of new ServiceNow development tool. ServiceNow is cloud based IT service support management tool. It is widely customizable, mainly by creating scripts. The problem is that scripts are created via web browser, which is not very user friendly. The main goal of this paper is to design better solution for creating scripts in ServiceNow and implement it for selected integrated development environment - Eclipse. Created development tool should support these oper...

  18. Clean Cities Now Vol. 19, No. 1

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-07-24

    Now is the official bi-annual newsletter of Clean Cities, an initiative designed to reduce petroleum consumption in the transportation sector by advancing the use of alternative and renewable fuels, fuel economy improvements, idle-reduction measures, and new technologies, as they emerge.

  19. Clean Cities Now Vol. 19, No. 2

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-12-18

    Clean Cities Now is the official bi-annual newsletter of Clean Cities, an initiative designed to reduce petroleum consumption in the transportation sector by advancing the use of alternative and renewable fuels, fuel economy improvements, idle-reduction measures, and new technologies, as they emerge.

  20. Clean Cities Now Vol. 20, No. 2

    Energy Technology Data Exchange (ETDEWEB)

    None

    2017-01-13

    Clean Cities Now is the official semi-annual newsletter of Clean Cities, an initiative designed to reduce petroleum consumption in the transportation sector by advancing the use of alternative and renewable fuels, fuel economy improvements, idle-reduction measures, and new technologies, as they emerge.

  1. Clean Cities Now Vol. 20, No. 1

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-06-13

    Clean Cities Now is the official semi-annual newsletter of Clean Cities, an initiative designed to reduce petroleum consumption in the transportation sector by advancing the use of alternative and renewable fuels, fuel economy improvements, idle-reduction measures, and new technologies, as they emerge.

  2. Cooling metals to the microkelvin regime, then and now

    Science.gov (United States)

    Pickett, G. R.

    2000-05-01

    Better understanding of the behaviour of materials and the techniques of nuclear cooling, gained in recent years, now allows us to cool metallic samples to the microkelvin regime, with hold times at the higher temperatures of tens of hours. In the early days of nuclear cooling when sources of heat leaks were hardly understood, such performance would have appeared an impossible dream. However, we are now at the point where solid state experiments can be realistically contemplated in the sub- 10 μK regime.

  3. Service management at CERN with Service-Now

    International Nuclear Information System (INIS)

    Toteva, Z; Fedorko, I; Hefferman, J; Lemaitre, S; Mira, O Pera; Alonso, R Alvarez; Cheimariou, M-E; Clavo, D Martin; Granda, E Alvarez; Pedreira, P Martinez

    2012-01-01

    The Information Technology (IT) and the General Services (GS) departments at CERN have decided to combine their extensive experience in support for IT and non-IT services towards a common goal – to bring the services closer to the end user based on Information Technology Infrastructure Library (ITIL) best practice. The collaborative efforts have so far produced definitions for the incident and the request fulfilment processes which are based on a unique two-dimensional service catalogue that combines both the user and the support team views of all services. After an extensive evaluation of the available industrial solutions, Service-now was selected as the tool to implement the CERN Service-Management processes. The initial release of the tool provided an attractive web portal for the users and successfully implemented two basic ITIL processes; the incident management and the request fulfilment processes. It also integrated with the CERN personnel databases and the LHC GRID ticketing system. Subsequent releases continued to integrate with other third-party tools like the facility management systems of CERN as well as to implement new processes such as change management. Independently from those new development activities it was decided to simplify the request fulfilment process in order to achieve easier acceptance by the CERN user community. We believe that due to the high modularity of the Service-now tool, the parallel design of ITIL processes e.g., event management and non-ITIL processes, e.g., computer centre hardware management, will be easily achieved. This presentation will describe the experience that we have acquired and the techniques that were followed to achieve the CERN customization of the Service-Now tool.

  4. Now consider diffusion

    International Nuclear Information System (INIS)

    Dungey, J.W.

    1984-01-01

    The authors want to talk about future work, but first he will reply to Stan Cowley's comment on his naivety in believing in the whole story to 99% confidence in '65, when he knew about Fairfield's results. Does it matter whether you make the right judgment about theories? Yes, it does, particularly for experimentalists perhaps, but also for theorists. The work you do later depends on the judgment you've made on previous work. People have wasted a lot of time developing on insecure or even wrong foundations. Now for future work. One mild surprise the authors have had is that they haven't heard more about diffusion, in two contexts. Gordon Rostoker is yet to come and he may talk about particles getting into the magnetosphere by diffusion. Lots of noise is observed and so diffusion must happen. If time had not been short, the authors were planning to discuss in a handwaving way what sort of diffusion mechanisms one might consider. The other aspect of diffusion he was going to talk about is at the other end of things and is velocity diffusion, which is involved in anomalous resistivity

  5. Integration : OPEC is now in 35 foreign refineries

    International Nuclear Information System (INIS)

    Terzian, P.

    1994-01-01

    Seven countries from OPEC own now share holdings in 35 foreign refineries. By this process of downstream reintegration, these countries hope to reach a better stability of crude oil prices. (Author). 3 tabs

  6. Clean Cities Now, Vol. 18, No. 2

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-01-19

    This is version 18.2 of Clean Cities Now, the official biannual newsletter of the Clean Cities program. Clean Cities is an initiative designed to reduce petroleum consumption in the transportation sector by advancing the use of alternative and renewable fuels, fuel economy improvements, idle-reduction measures, and new technologies, as they emerge.

  7. FIRE PERMIT NOW ON EDH!

    CERN Multimedia

    TIS General Safety Group or

    2001-01-01

    The electronic version of the Fire Permit form is now active. The aim of the Fire Permit procedure is to reduce the risk of fire or explosion. It is mandatory when performing 'hot work' (mainly activities which involve the use of naked flames or other heat sources - e.g. welding, brazing, cutting, grinding, etc.). Its use is explained in the CERN Fire Protection Code E. (Fire Protection) The new electronic form, which is substantially unchanged from the previous authorizing procedure, will be available on the Electronic Document Handling system (https://edh.cern.ch/) as of 1st September 2001. From this date use of the paper version should be discontinued.

  8. Proposals now being accepted for 'INCITE'

    CERN Multimedia

    2003-01-01

    Secretary of Energy, Spencer Abraham, has announced that proposals are now being accepted for a new DOE Office of Science program to support innovative, large-scale computational science projects. The program, entitled "Innovative and Novel Computational Impact on Theory and Experiment" will award a total of 4.5 million supercomputer processor hours and 100 trillion bytes of data storage space at the National Energy Research Scientific Computing Center at DOE's Lawrence Berkeley National Laboratory (1 page).

  9. Nation Building in Palestine - The Time is Now

    National Research Council Canada - National Science Library

    Maclean, David

    2002-01-01

    .... That being said, it may seem counterintuitive to pursue relations now with a non-state, especially one in conflict with one of our closest and enduring allies, and currently perceived as one who at a...

  10. Now you see it, now you don't: The ozone hole

    International Nuclear Information System (INIS)

    Wilkniss, P.E.

    1990-01-01

    Fragile, rainbow-colored clouds high in the antarctic sky are a beautiful but onerous reminder that all is not well in the universe. To the trained scientist, the clouds foretell the destruction of Antarctic ozone - a gas that protects the Earth from the sun's destructive ultraviolet rays. The author describes the scene while telling of the Dr. Jekyll/Mr. Hyde role that ozone plays in the environment. In the lower atmosphere, ozone is a nasty pollutant. In the upper atmosphere, it shields the Earth's surface from unwanted ultraviolet radiation. A bombshell was dropped in 1985 by the discovery of a large hole in the ozone layer in the upper atmosphere over the entire expanse of Antarctica. The hole later confirmed in other studies, has been appearing each spring and disappearing each summer since 1975. The mass of scientific evidence leaves no doubt that chlorine from chlorofluorocarbons (CFCs) is responsible for destroying the ozone. He predicts the hole will remain for 50 to 100 years, even if the world were to stop releasing CFCs now, although the size of the hole will wax and wane. Increased ultraviolet radiation resulting from the ozone depletion will cause an increase in skin cancer, cataracts, and infection due to weakened immune systems

  11. The Now Age, New Space, and Transforming the Exploration of Geospace

    Science.gov (United States)

    Paxton, L. J.

    2017-12-01

    In this talk I will discuss: 1) Changing our description of how and why we do Heliophysics (NASA) and Geospace Science (NSF) research 2) How we can take advantage of the New Space industry capabilities 3) How and why we can use the technology that has begun the transformation of our society into the "Now Age" I will discuss trends that I see that enable, if we have the will, a fundamental revitalization of the science that we aspire to do. I will focus on our opportunities to revolutionize the exploration of geospace (the region below about 1000km) and how that addresses fundamental questions about our place in the universe. Exploration of space, in particular exploration of geospace, is at a cusp - we can either attempt to continue to move forward using the same, tried and true techniques or we can embrace the "Now Age" and the capabilities enabled by the New Space industry to move forward to a fuller understanding of our world's place in the solar system. Heliophysics at NASA and Geospace Science at NSF can be recast as fundamental exploratory basic research that asks and answers questions that everyone can understand. We are in the Now Age because the human race has enabled and embraced a fundamentally different way of accessing information and, potentially gaining knowledge. For the first time, we have the capability to provide essentially all of recorded human knowledge immediately and to anyone - and people want that access "now". Even in the scientific community we expect to be able to see the latest data right now. This is enabled by the internet and ubiquitous connectivity; low cost data storage and memory; fast, low-cost computing; the means to visualize the information; advances in the way we store, catalog and retrieve information; and advances in modeling and simulation. Concomitant with the Now Age, and providing an impetus to do things "now", the New Space industry has enabled low cost access to space and has embraced a vision of human presence in

  12. CERN HUMAN RESSOURCES 1999 FRENCH VERSION NOW AVAIABLE

    CERN Multimedia

    Division du Personnel

    1999-01-01

    A report on CERN Human Resources is published once every two years. The version of the 1999 report is now available in French and in English: in your divisional secretariat for paper copieson the Web: http://www.cern.ch/HRreportIn its foreword, the Director-General addresses some key issues:'Many (…) key personnel are now steadily approaching retirement. (…) More efficient working methods and new technology can absorb not all the natural depletion. New blood is vital, and about a hundred new people are taken on each year'About the RSL programme, he says:'… More than 30 additional posts have been opened by this voluntary scheme. This programme displays the excellent mutual understanding that has been carefully built up between CERN management and staff. This harmonious atmosphere bodes well for continued success.'The Human Resources 1999 report gives information on a lot of subjects:general information on CERN's aim and the organisation of its operations,major changes in recent years...

  13. ACTT Now: A Collaboration Reshaping Teacher Technology Training.

    Science.gov (United States)

    Curry-Corcoran, Daniel E.; O'Shea, Patrick M.

    2003-01-01

    Describes the ACTT Now (Aligning Certification with Technology Training) project in Brunswick County Public Schools (Virginia) that, in partnership with Old Dominion University (Norfolk, VA), has created a Field-Based Master's Program to help overcome the disadvantages of a small, rural district in providing teacher training for technology…

  14. Artists and now also activists to contrast global warming (Italian original version

    Directory of Open Access Journals (Sweden)

    Alessandra Drioli

    2008-09-01

    Full Text Available Artists create new aesthetics to communicate new messages and new concerns. Apprehension about the climate, its changes, global warming and a disposition to anxiously running after an ideal sustainable development are part of the issues we all now experience with a certain degree of anxiety. This is why the sensitive antennae of artists have perceived and evolved that. Now they are committed on many fields to making their voice be heard and to raising ethical and social issues, also regarding the scientific instruments man possesses to manipulate nature. So they have now accessed the group of special interlocutors in the dialogue between science and society.

  15. News coverage of climate change in Nature News and ScienceNOW during 2007

    DEFF Research Database (Denmark)

    Nielsen, Kristian Hvidtfelt; Kjærgaard, Rikke Schmidt

    2011-01-01

    of appreciating climate change, its severe consequences, and its anthropogenic causes. During that year the two journals’ online news services Nature News and ScienceNOW framed climate change to fit particular agendas resulting in markedly different narratives. This article demonstrates that Nature News reported...... more critically on political decisions, scientific results, and social matters of climate change compared to ScienceNOW. Operating under different institutional constraints ScienceNOW generally took a more cautious line. The evidence drawn from both textual and visual analyses shows that news sections...

  16. HashLearn Now: Mobile Tutoring in India

    OpenAIRE

    Arun Kumar Agariya; Binay Krishna Shivam; Shashank Murali; Jyoti Tikoria

    2016-01-01

    Looking at today’s competitive exams scenario, a single mark may lead to a differentiation of rank in multiples of hundreds or even thousands. Looking at this problem from student’s perspective this article discusses the role of anywhere, anytime help for the students in getting answers for their problems on a real-time basis from the application known as HashLearn Now. The smart phones usage by students clearly signifies the importance of this application for getting their queries answered b...

  17. Energy transition, is it now?

    International Nuclear Information System (INIS)

    Combe, Matthieu; Thouverez, Pierre

    2016-06-01

    As French energy policy is now defined for energy transition, the contributions of this publication discuss implemented measures, what new laws will change, and what will be the consequences for industry. A first set of articles thus comments evolutions related to the implementation of energy transition in the building sector, how energy transition wants to get rid of wastage, how energy transition will impact the transport sector (public transports, car-pool and car sharing, bicycle, retail sector, airfields), and outline that President Hollande has fulfilled (nearly) all his commitments. The next article comments changes and critics made by the French constitutional Council on the law for energy transition. The next set of articles comments the results of an ADEME's study on bicycle kilometre allowance, discusses the issue of energy safety, and comments statements made by candidates to the French President election of 2012 on nuclear energy after the Fukushima accident

  18. Canon multifunction copier machines – now with onsite support!

    CERN Document Server

    2013-01-01

    Following a retendering process in 2012, the IT Department is pleased to announce that leased multifunction copier machines are now covered by onsite support, provided by Canon technicians via the CERN Service Desk support system.   You can now contact the Service Desk regarding any problems or requests for toner: Telephone: 77777 Email: Service-Desk@cern.ch Please remember to quote the machine printer name and/or serial number (marked on the side of the machine). The following submission forms are available online: Report a failure with a printer or copier Request for network printer or copier installation or move Request toner/ink for my printer or copier The website below details the range of models available, all of which include print, photocopy and scan-to-mail functions as standard. These multifunction copier machines are leased subject to a monthly charge (minimum of 48 months) plus a “per click” charge to cover consumables (except staples), leaving you noth...

  19. PLATO[R] Achieve Now. What Works Clearinghouse Intervention Report

    Science.gov (United States)

    What Works Clearinghouse, 2010

    2010-01-01

    "PLATO[R] Achieve Now" is a software-based curriculum for the elementary and middle school grades. Instructional content is delivered via the PlayStation Portable (PSP[R]) system, allowing students to access learning materials in various settings. Software-based assessments are used to customize individual instruction, allowing students…

  20. TV review: Nova scienceNOW - Season 2, Episode 4

    CERN Multimedia

    Lasser, Josh

    2007-01-01

    "Sitting down to watch the fourth episode of the second season of Nova ScienceNOW I'm mainly struck by one thought: why have they only put out four epidoses nearly nine months into their second season? The second story is all about CERN and the LHC. (2 pages)

  1. Migration of the CERN IT data centre support system to ServiceNow

    International Nuclear Information System (INIS)

    Alvarez Alonso, R; Arneodo, G; Barring, O

    2014-01-01

    The large potential and flexibility of the ServiceNow infrastructure based on 'best practises' methods is allowing the migration of some of the ticketing systems traditionally used for the monitoring of the servers and services available at the CERN IT Computer Centre. This migration enables the standardization and globalization of the ticketing and control systems implementing a generic system extensible to other departments and users. One of the activities of the Service Management project together with the Computing Facilities group has been the migration of the ITCM structure based on Remedy to ServiceNow within the context of one of the ITIL processes called Event Management. The experience gained during the first months of operation has been instrumental towards the migration to ServiceNow of other service monitoring systems and databases. The usage of this structure is also extended to the service tracking at the Wigner Centre in Budapest.

  2. Migration of the CERN IT Data Centre Support System to ServiceNow

    Science.gov (United States)

    Alvarez Alonso, R.; Arneodo, G.; Barring, O.; Bonfillou, E.; Coelho dos Santos, M.; Dore, V.; Lefebure, V.; Fedorko, I.; Grossir, A.; Hefferman, J.; Mendez Lorenzo, P.; Moller, M.; Pera Mira, O.; Salter, W.; Trevisani, F.; Toteva, Z.

    2014-06-01

    The large potential and flexibility of the ServiceNow infrastructure based on "best practises" methods is allowing the migration of some of the ticketing systems traditionally used for the monitoring of the servers and services available at the CERN IT Computer Centre. This migration enables the standardization and globalization of the ticketing and control systems implementing a generic system extensible to other departments and users. One of the activities of the Service Management project together with the Computing Facilities group has been the migration of the ITCM structure based on Remedy to ServiceNow within the context of one of the ITIL processes called Event Management. The experience gained during the first months of operation has been instrumental towards the migration to ServiceNow of other service monitoring systems and databases. The usage of this structure is also extended to the service tracking at the Wigner Centre in Budapest.

  3. 76 FR 10395 - BreconRidge Manufacturing Solutions, Now Known as Sanmina-SCI Corporation, Division...

    Science.gov (United States)

    2011-02-24

    ... Solutions, Now Known as Sanmina-SCI Corporation, Division Optoelectronic and Microelectronic Design and Manufacturing, a Subsidiary of Sanmina-SCI Corporation, Including On- Site Leased Workers From Kelly Services... Manufacturing Solutions, now known as Sanmina-SCI Corporation, Division Optoelectronic and Microelectronic...

  4. MeSH Now: automatic MeSH indexing at PubMed scale via learning to rank.

    Science.gov (United States)

    Mao, Yuqing; Lu, Zhiyong

    2017-04-17

    MeSH indexing is the task of assigning relevant MeSH terms based on a manual reading of scholarly publications by human indexers. The task is highly important for improving literature retrieval and many other scientific investigations in biomedical research. Unfortunately, given its manual nature, the process of MeSH indexing is both time-consuming (new articles are not immediately indexed until 2 or 3 months later) and costly (approximately ten dollars per article). In response, automatic indexing by computers has been previously proposed and attempted but remains challenging. In order to advance the state of the art in automatic MeSH indexing, a community-wide shared task called BioASQ was recently organized. We propose MeSH Now, an integrated approach that first uses multiple strategies to generate a combined list of candidate MeSH terms for a target article. Through a novel learning-to-rank framework, MeSH Now then ranks the list of candidate terms based on their relevance to the target article. Finally, MeSH Now selects the highest-ranked MeSH terms via a post-processing module. We assessed MeSH Now on two separate benchmarking datasets using traditional precision, recall and F 1 -score metrics. In both evaluations, MeSH Now consistently achieved over 0.60 in F-score, ranging from 0.610 to 0.612. Furthermore, additional experiments show that MeSH Now can be optimized by parallel computing in order to process MEDLINE documents on a large scale. We conclude that MeSH Now is a robust approach with state-of-the-art performance for automatic MeSH indexing and that MeSH Now is capable of processing PubMed scale documents within a reasonable time frame. http://www.ncbi.nlm.nih.gov/CBBresearch/Lu/Demo/MeSHNow/ .

  5. Where are we now on nuclear power?

    International Nuclear Information System (INIS)

    Oppenheimer, A.

    1991-01-01

    Discussion at the March 1991 Conference of the institute of Energy 'Where are we now on Nuclear Power' is summarized. Speakers from the Institution of Nuclear Engineers, Nuclear Electric, the European Commission Energy Directorate, British Nuclear Fuels, Scottish Nuclear and others looked at the economic aspects and the safety and pollution record of nuclear power in the United Kingdom. Technically, nuclear power is doing well although political problems remain. There was a problem of retaining skilled people in the absence of an assured construction programme. However there was a mood of cautious optimism over the future of nuclear power in the UK. (UK)

  6. Brazilian Studies Then and Now

    Directory of Open Access Journals (Sweden)

    Anthony Pereira

    2012-09-01

    Full Text Available In 1912 the Brazilian diplomat and scholar Manuel de Oliveira Lima gave six lectures at Stanford University that encapsulated his views of what we now call Brazilian Studies. This article summarizes Oliveira Lima’s lectures. It then points out three aspects of Oliveira Lima’s worldview that are problematic from the perspective of the twenty-first century: his Eurocentrism; the unproblematic nature of the nation-state in his thinking; and his largely negative view of Brazil’s racial heritage. The third part of the essay analyzes three aspects of Oliveira Lima’s lectures that are still contemporary. These are the need to establish an adequate comparative context for the study of Brazil; the difficulty of justifying an academic discipline that revolves around the study of a single country; and the challenge of uniting disparate and specialized disciplines in order to appreciate Brazil’s complexity and trajectory in the modern world. In the conclusion, some guidelines for maintaining Brazilian Studies as a vibrant field are suggested.

  7. Globalization Then and Now: Increasing Scale Reduces Local Sustainability

    Science.gov (United States)

    Joseph A. Tainter

    2006-01-01

    One consequence of globalization is that parts of the world that were once remote and minimally influenced by broader political and economic developments now find themselves profoundly affected by forces beyond their comprehension. Communities that were once self-sufficient and resilient come to depend on larger systems, no longer control their own destinies, and...

  8. SeisComP 3 - Where are we now?

    OpenAIRE

    Joachim Saul; Jan Becker; Winfried Hanka; Andres Heinloo; Bernd Weber

    2010-01-01

    The seismological software SeisComP has evolved within the last approximately 10 years from a pure acquisition modules to a fully featured real-time earthquake monitoring software. The now very popular SeedLink protocol for seismic data transmission has been the core of SeisComP from the very beginning. Later additions included simple, purely automatic event detection, location and magnitude determination capabilities. Especially within the development of the 3rd-generation SeisComP, also kno...

  9. HEALTH INSURANCE: our money in a capitalized fund now

    CERN Multimedia

    Association du personnel

    In ECHO no. 41 on 5 November “Health insurance: what is the current situation?” we explained to you the situation of our Health Insurance Scheme and the ideas currently being discussed to ensure its future balance. If you missed this episode, you should catch up on it now so that you understand what follows.

  10. Actos Now for the prevention of diabetes (ACT NOW study

    Directory of Open Access Journals (Sweden)

    Reaven Peter D

    2009-07-01

    Full Text Available Abstract Background Impaired glucose tolerance (IGT is a prediabetic state. If IGT can be prevented from progressing to overt diabetes, hyperglycemia-related complications can be avoided. The purpose of the present study was to examine whether pioglitazone (ACTOS® can prevent progression of IGT to type 2 diabetes mellitus (T2DM in a prospective randomized, double blind, placebo controlled trial. Methods/Design 602 IGT subjects were identified with OGTT (2-hour plasma glucose = 140–199 mg/dl. In addition, IGT subjects were required to have FPG = 95–125 mg/dl and at least one other high risk characteristic. Prior to randomization all subjects had measurement of ankle-arm blood pressure, systolic/diastolic blood pressure, HbA1C, lipid profile and a subset had frequently sampled intravenous glucose tolerance test (FSIVGTT, DEXA, and ultrasound determination of carotid intima-media thickness (IMT. Following this, subjects were randomized to receive pioglitazone (45 mg/day or placebo, and returned every 2–3 months for FPG determination and annually for OGTT. Repeat carotid IMT measurement was performed at 18 months and study end. Recruitment took place over 24 months, and subjects were followed for an additional 24 months. At study end (48 months or at time of diagnosis of diabetes the OGTT, FSIVGTT, DEXA, carotid IMT, and all other measurements were repeated. Primary endpoint is conversion of IGT to T2DM based upon FPG ≥ 126 or 2-hour PG ≥ 200 mg/dl. Secondary endpoints include whether pioglitazone can: (i improve glycemic control (ii enhance insulin sensitivity, (iii augment beta cell function, (iv improve risk factors for cardiovascular disease, (v cause regression/slow progression of carotid IMT, (vi revert newly diagnosed diabetes to normal glucose tolerance. Conclusion ACT NOW is designed to determine if pioglitazone can prevent/delay progression to diabetes in high risk IGT subjects, and to define the mechanisms (improved insulin

  11. Nowe zasady działalności firm audytorskich

    Directory of Open Access Journals (Sweden)

    Kazimierz Sawicki

    2009-03-01

    Full Text Available W artykule przedstawiono zmiany, stanowiące implementację Dyrektywy 2006/43/WE Unii Europejskiej w części dotyczącej funkcjonowania firm audytorskich w Polsce. Zgłoszono uwagi popierające nowe rozwiązania, jak też zawierające wątpliwości dotyczące skuteczności ich stosowania w praktyce.

  12. Natural language processing and the Now-or-Never bottleneck.

    Science.gov (United States)

    Gómez-Rodríguez, Carlos

    2016-01-01

    Researchers, motivated by the need to improve the efficiency of natural language processing tools to handle web-scale data, have recently arrived at models that remarkably match the expected features of human language processing under the Now-or-Never bottleneck framework. This provides additional support for said framework and highlights the research potential in the interaction between applied computational linguistics and cognitive science.

  13. The Principles of Economics from Now until Then: A Response.

    Science.gov (United States)

    McConnell, Campbell R.

    1988-01-01

    Responding to Bell's article "The Principles of Economics from Now until Then," McConnell focuses on several issues of disagreement. Discusses competing macroeconomic theories, the internationalization of textbooks, pedagogical priorities, and the future of economics textbooks. Argues that professors need to do a more objective job of…

  14. Panel: If I Only Knew Then What I Know Now

    Science.gov (United States)

    Goals Recycling Green Purchasing Pollution Prevention Reusing Water Resources Environmental Management Discussion and Networking Event Panel: If I Only Knew Then What I Know Now WHEN: May 16, 2016 2:30 PM - 5:00 Alamos CONTACT: Veronika Mocko CATEGORY: Community INTERNAL: Calendar Login Event Description The LANL

  15. The Concept of now in Dogen's Philosophy

    Science.gov (United States)

    Luetchford, Michael Eido

    Belief in the totality of the present moment forms one of the fundamental tenets of Buddhist philosophy. According to Buddhist thought, the past is not real, because it no longer exists, and the future is not real because it has not yet come into existence. Only the present moment is real existence. Early Buddhist philosophers developed a theory of existence as a point-instant, and this view finds parallels in the poetry of T.S. Eliot. The 13th century monk/philosopher Dogen wrote extensively about our concept of time set against our experience of time. In his masterwork, Shobogenzo, he expounds on the nature of the Now in a stimulating essay rich in imagery and metaphor.

  16. Clinical Application of Pharmacogenetics: Where are We Now?

    Science.gov (United States)

    2014-01-01

    Pharmacogenetic (PGx) testing has the potential to improve drug therapy in an individual by informing appropriate drug dosing or drug selection in order to maximize efficacy and safety. Although multiple studies have illustrated the potential benefits of such testing when applied to specific drugs across a broad range of therapy areas, the uptake of PGx testing in routine clinical practice has been relatively limited. Implementation appears to be hampered by the absence of sufficiently strong evidence linking the results of testing with actionable benefits in terms of clinical outcomes. Meanwhile, there are now adequate data to allow dosing recommendations as have been developed by bodies including the Dutch Pharmacogenetics Working Group (DPWG) and the Clinical Pharmacogenetics Implementation Consortium (CPIC) in several settings, including TPMT/thiopurines, CYP2C19/clopidogrel, CYP2D6/codeine, VKORC1-CYP2C9/warfarin, HLA-B*5701/abacavir, SLCO1B1/simvastatin and HLAB*5801/allopurinol. The International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) and the International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) have also recently initiated surveys in order to better understand the extent of, and the role played by, PGx testing in clinical practice. This should help identify where further training and education may be beneficial. To this end, in collaboration with ESPT, the IFCC Pharmacogenetic Laboratory Network has now been formed, with the aim of improving the uptake and quality of PGx testing. PMID:27683445

  17. The Principles of Economics from Now until Then: A Comment.

    Science.gov (United States)

    Amacher, Ryan C.

    1988-01-01

    Comments on Bell's article "The Principles of Economics from Now until Then," responding to the author's two general premises as well as citing specific arguments. Concludes that Bell's premises are based on a small and unrepresentative number of textbooks. Many textbooks that present material according to the recommendations were…

  18. Apocalypse now, Vietnam and the rhetoric of influence

    Directory of Open Access Journals (Sweden)

    Jeffrey Childs

    2014-03-01

    Full Text Available Readings of Francis Ford Coppola's Apocalypse Now (1979 often confront the difficulty of having to privilege either its aesthetic context (considering, for instance, its relation to Conrad's Heart of Darkness [1899] or to the history of cinema or its value as a representation of the Vietnam War. In this paper, I will argue that viewing the film as a meditation on the nature and rhetoric of influence allows us to bridge this gap and provides us with valuable insights into both the film's aesthetic precursors and the circumstances of its historical setting.

  19. Living the future now: `Race' and challenges of transformation in ...

    African Journals Online (AJOL)

    Living the future now: `Race' and challenges of transformation in higher education. ZE Erasmus. Abstract. Drawing on research among medical students at the University of Cape Town's Faculty of Health Sciences, this article explores two questions: How do students and staff work with `race' in their relations to one another?

  20. Financial provisions needed now to deal with future waste

    International Nuclear Information System (INIS)

    Olivier, J.-P.

    1978-01-01

    Some opinions, derived from a recent NEA/OECD report, are expressed on the financing of radioactive waste disposal. Waste disposal could represent 50% of total waste management costs but it will be some time before waste disposal must be paid for and accurate estimation of the costs is almost impossible. An international fund set up now would overcome many of the financing problems that are likely to arise

  1. Dose constraints, what are they now?

    International Nuclear Information System (INIS)

    Lazo, T.

    2005-01-01

    The concept of a source-related dose constraint was first introduced in ICPR publication 60. The idea was to provide a number that individual exposures from a single, specific source should not exceed, and below which optimisation of protection should take place. Dose constraints were applied to occupational and public exposures from practices. In order to simplify and clarify the ICRP's recommendations, the latest draft, RPO5, presents dose constraints again, and with the same meaning as in publication 60. However, the dose constraints are now applied in all situations, not just practices. This new approach does provide simplification, in that a single concept is applied to all types of exposures (normal situations, accident situations, and existing situations). However, the approach and numerical values that are selected by regulatory authorities for the application of the concept, particularly in normal situations which are also subject to dose limits, will be crucial to the implementation of the system of radiological protection. (author)

  2. Making better places urban design now

    CERN Document Server

    Hayward, Richard

    2013-01-01

    Making Better Places: Urban Design Now discusses how to make better places: how monotonous or rich urban development can be, how appropriate to traffic requirements urban improvements are, or how sustainable an urban design approach can be to existing and future urban dispersal. The book reviews the gap existing between the various environmental disciplines leading to the emergence of urban design; as well as the gap between the rhetoric and practical achievements of urban design. The practice of urban design entails the premise that environments are to be created and transformed to provide the most opportunities for the largest number of people. By using an urban tissue plan, the urban developmental planner can produce and evaluate site development appraisal and design proposals. The book also provides an abstract perspective that considers built forms as a set of signs to provide a mechanism which shows the modification of urban space. The text also addresses the issue of urban change in established centers...

  3. I made a website! Now what?

    CERN Multimedia

    CERN. Geneva

    2017-01-01

    When you finish your website (or a web app) and you are ready to show it to the world, it's not the end of your work, it's just the beginning. Users will ask you to add new features, some bugs will be discovered or you will simply have to answer some emails about the website. But before this happens, you need to put is somewhere, so people can see it and start using it. Now, how do you select which of the 1047 different hosting companies will be the best? Or where do you get a cheap domain? How do you know that your website is up and running when you don't look or how do you communicate with people who subscribed to your newsletter? You don't know? Don't worry, during this talk I will give you some examples of tools and services that you can use when launching your website (with an emphasis on cheap/free and reliable tools).

  4. Radiation protection training then and now

    International Nuclear Information System (INIS)

    Mulleavy, T.

    1988-01-01

    Prior to the accident at Three Mile Island, the radiological control training was provided by the health physics and the chemistry departments. The programs that required the input from the health physics department were the Operations Training and the General Employee Training Programs, which were formally organized and presented radiological controls practices as part of the course objectives. The operations training section periodically requested the health physics department management to provide a radiological portion to their operator qualification or operations requalification class. After the accident in 1979, the General Employee Training Program administration was taken over by the operation training department where it underwent changes with a dedicated effort. The Operations Training Program also underwent a change as well as the Radiological Control Technician Training Program. Each group now has a specialty program designed for their specific needs. These programs have been designed using the Institute of Nuclear Power Operations and regulator guidelines

  5. New evaluation tool now available to assess research quality | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-04-25

    Apr 25, 2016 ... New evaluation tool now available to assess research quality ... Ratings on a scale defined by rubrics, to indicate the level at which a project ... Report: The value-for-money discourse: risks and opportunities for research for development ... Copyright · Open access policy · Privacy policy · Research ethics ...

  6. High prices on electric power now again?

    International Nuclear Information System (INIS)

    Doorman, Gerard

    2003-01-01

    Deregulation of the electric power market has yielded low prices for the consumers throughout the 1990s. Consumption has now increased considerably, but little new production has been added. This results in high prices in dry years, but to understand this one must understand price formation in the Nordic spot market. The high prices are a powerful signal to the consumers to reduce consumption, but they are also a signal to the producers to seize any opportunity to increase production. However, the construction of new dams etc. stirs up the environmentalists. Ordinary consumers may protect themselves against high prices by signing fixed-price contracts. For those who can tolerate price fluctuations, spot prices are a better alternative than the standard contract with variable price

  7. Happy birthday WWW: the web is now old enough to drive

    CERN Document Server

    Gilbertson, Scott

    2007-01-01

    "The World Wide Web can now drive. Sixteen years ago yeterday, in a short post to the alt.hypertext newsgroup, tim Berners-Lee revealed the first public web pages summarizing his World Wide Web project." (1/4 page)

  8. Linguistics, cognitive psychology, and the Now-or-Never bottleneck.

    Science.gov (United States)

    Endress, Ansgar D; Katzir, Roni

    2016-01-01

    Christiansen & Chater (C&C)'s key premise is that "if linguistic information is not processed rapidly, that information is lost for good" (sect. 1, para. 1). From this "Now-or-Never bottleneck" (NNB), C&C derive "wide-reaching and fundamental implications for language processing, acquisition and change as well as for the structure of language itself" (sect. 2, para. 10). We question both the premise and the consequentiality of its purported implications.

  9. The policy regarding cooperative sector in Cuba since 1959 until now

    Directory of Open Access Journals (Sweden)

    Claudia María Caballero Reyes

    2016-07-01

    Full Text Available The policy regarding cooperative sector developed by the country since the triumph of Cuban revolution up to now has been focused on integral development. According to this point of view the goals are linked, combining the solutions of social, economic, environmental and cultural problems. This paper proposes a systematization of that policy focused on the different periods that it has gone through since 1959 until now. In each one has been arise a cooperative form, maintaining the previous forms: the Credit and Service Cooperatives (CCS, the Agricultural Production Cooperatives (CPA, the Basic Units of Agricultural Production (UBPC and the Non-Agricultural Cooperatives. This progresses has been accompanied whit other distinct features that tinge each period y and up t which attention is granted, like contextual factors and social consequences of the actions set up in each period.

  10. Where Does The Brexit Debate Stand In The United Kingdom Right Now?

    DEFF Research Database (Denmark)

    Manners, Ian James

    2016-01-01

    On the 11th October 2016 the opposition Labour Party presented the ruling Conservative UK government with a list of 170 questions – one for each day before Teresa May’s self-imposed deadline to start the process of leaving the EU. A more realistic list of questions in the UK’s ‘Brexit’ debate right...... now would consist of 17 000 questions – the four decade-old UK-EU relationship raises so many questions that it would take that many days (46 years) to address them. This briefing will focus on three factors in the UK right now – referendum context, UK gov-ernment, and Brexit debate – with a specific...

  11. What we now know (and don't know) about reactor safety

    International Nuclear Information System (INIS)

    Budnitz, R.J.

    1984-01-01

    This paper deals with the likelihood and consequences of major reactor accidents. Our understanding has advanced markedly in the past decade, largely because of the use of probabilistic risk assessment. There is now a good understanding of accident sequences, despite some important gaps. The insights achieved have in many ways revolutionized the reactor safety community's view of the relative importance of various safety issues. Understanding of severe accident phenomena is still inadequate, but experiments and development of analytical methods will soon enable us to calculate better the phenomena involved in core degradation, core melting, containment behavior, and the ultimate fate of fission products released from a melted core. Also we are now gaining important insights into analysis of human errors and external initiating events. Thus the next decade will see another quantum jump in our understanding, rivalling the progress of the last decade. (author)

  12. Eimeria genomics: Where are we now and where are we going?

    Science.gov (United States)

    Blake, Damer P

    2015-08-15

    The evolution of sequencing technologies, from Sanger to next generation (NGS) and now the emerging third generation, has prompted a radical frameshift moving genomics from the specialist to the mainstream. For parasitology, genomics has moved fastest for the protozoa with sequence assemblies becoming available for multiple genera including Babesia, Cryptosporidium, Eimeria, Giardia, Leishmania, Neospora, Plasmodium, Theileria, Toxoplasma and Trypanosoma. Progress has commonly been slower for parasites of animals which lack zoonotic potential, but the deficit is now being redressed with impact likely in the areas of drug and vaccine development, molecular diagnostics and population biology. Genomics studies with the apicomplexan Eimeria species clearly illustrate the approaches and opportunities available. Specifically, more than ten years after initiation of a genome sequencing project a sequence assembly was published for Eimeria tenella in 2014, complemented by assemblies for all other Eimeria species which infect the chicken and Eimeria falciformis, a parasite of the mouse. Public access to these and other coccidian genome assemblies through resources such as GeneDB and ToxoDB now promotes comparative analysis, encouraging better use of shared resources and enhancing opportunities for development of novel diagnostic and control strategies. In the short term genomics resources support development of targeted and genome-wide genetic markers such as single nucleotide polymorphisms (SNPs), with whole genome re-sequencing becoming viable in the near future. Experimental power will develop rapidly as additional species, strains and isolates are sampled with particular emphasis on population structure and allelic diversity. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. 'I know they are distressed. What do I do now?'.

    Science.gov (United States)

    Moorey, Stirling

    2013-09-01

    Significant advances have been made in our understanding of psychological adjustment to cancer over the last 40 years. Most clinicians now recognise the importance of psychosocial factors and the need for skills in emotional support. In the first phase of psycho-oncology, pioneering work in the 1970s and 1980s mapped the extent of psychological morbidity in cancer. This has been followed by a second phase where clinical trials have demonstrated that psychological treatments are effective. But although clinicians may feel more confident in identifying distress and listening to the patient, they rarely feel confident that they possess the skills to help. This paper will review the progress through the first two phases and argue that we are now in the third phase where we can begin to examine methods for delivering cost-effective psychological care. One of these methods is to equip staff with basic skills to understand and manage psychological distress. This paper will also describe a programme over the last 10 years to evaluate the effectiveness and clinical impact of such training for palliative care professionals. Copyright © 2013 John Wiley & Sons, Ltd.

  14. ORIENTING OF ATTENTION: THEN AND NOW1

    Science.gov (United States)

    Posner, Michael I.

    2014-01-01

    It is nearly 35 years since I gave the 7th Sir Frederick Bartlett lecture at Oxford University. This was published as a paper entitled Orienting of Attention in the Quarterly Journal (1980, 32: 3–25). The topic was then primarily in Psychology, but now equally often in Neuroscience. This paper summarizes the background of the reaction time methods used in the original paper and findings that emerged later on the sensory consequences of orienting, mainly in the visual system. It then discusses the brain network which is the source of the sensory amplification and other brain networks that are involved in attention. Next, it reviews studies of the development of attentional networks in early life. Finally, it indicates how the new tools available to explore the human brain can lead to further progress. PMID:25176352

  15. Social Media and Pathology: Where Are We Now and Why Does it Matter?

    Science.gov (United States)

    Isom, James; Walsh, Meggen; Gardner, Jerad M

    2017-09-01

    Social media has exploded in popularity in recent years. It is a powerful new tool for networking, collaborating, and for the communication and evolution of ideas. It has been increasingly used for business purposes and is now being embraced by physicians including pathologists. Pathology professional organizations and even peer-reviewed pathology journals are now beginning to use social media, as well. There are multiple social media platforms, including Twitter, Facebook, Instagram, LinkedIn, and others. Each platform has different audiences and different ways to share content and interact with other users. This paper discusses the different social media platforms and how they are being used in pathology currently.

  16. Evaluation of QuitNow Men: An Online, Men-Centered Smoking Cessation Intervention.

    Science.gov (United States)

    Bottorff, Joan L; Oliffe, John L; Sarbit, Gayl; Sharp, Paul; Caperchione, Cristina M; Currie, Leanne M; Schmid, Jonathan; Mackay, Martha H; Stolp, Sean

    2016-04-20

    Men continue to smoke cigarettes in greater numbers than women. There is growing evidence for the value of developing targeted, men-centered health promotion programs. However, few smoking cessation interventions have been designed for men. A gender-specific website, QuitNow Men, was developed based on focus group interview findings, stakeholder feedback, and evidence-based cessation strategies. The website was designed to incorporate a masculine look and feel through the use of images, direct language, and interactive content. Usability experts and end-users provided feedback on navigation and functionality of the website prior to pilot testing. The objectives of the pilot study were to describe (1) men's use and evaluations of the interactive resources and information on the QuitNow Men website, and (2) the potential of QuitNow Men to engage men in reducing and quitting smoking. A one-group, pretest-posttest study design was used. Men who were interested in quitting were recruited and invited to use the website over a 6-month period. Data were collected via online questionnaires at baseline, 3-month, and 6-month follow-up. A total of 117 men completed the baseline survey. Over half of those (67/117, 57.3%) completed both follow-up surveys. At baseline, participants (N=117) had been smoking for an average of 24 years (SD 12.1) and smoked on average 15 cigarettes a day (SD 7.4). The majority had not previously used a quit smoking website (103/117, 88.0%) or websites focused on men's health (105/117, 89.7%). At the 6-month follow-up, the majority of men used the QuitNow Men website at least once (64/67, 96%). Among the 64 users, 29 (43%) reported using the website more than 6 times. The men using QuitNow Men agreed or strongly agreed that the website was easy to use (51/64, 80%), the design and images were appealing (42/64, 66%), they intended to continue to use the website (42/64, 66%), and that they would recommend QuitNow Men to others who wanted to quit (46

  17. Nowe kryteria klasyfikacyjne reumatoidalnego zapalenia stawów

    Directory of Open Access Journals (Sweden)

    Ewa Stanisławska-Biernat

    2010-12-01

    Full Text Available W artykule przedstawiono nowe kryteria klasyfikacyjne reumatoidalnegozapalenia stawów (RZS, opracowane pierwszy raz przezwspólną grupę roboczą badaczy amerykańskich – z AmerykańskiegoKolegium Reumatologicznego (ACR – i europejskich – z EuropejskiejLigi Przeciwreumatycznej (EULAR. Omówiono przyczynywprowadzenia nowych kryteriów oraz zasady ich opracowywania.Na podstawie prac nad nowymi kryteriami wymieniono objawy klinicznei wyniki badań dodatkowych, które są czynnikami ryzykaprzetrwałego albo nadżerkowego zapalenia stawów. Przedstawionosposób posługiwania się nowymi kryteriami ACR/EULAR 2010dla RZS. Zwrócono także uwagę na ewentualne konsekwencjewprowadzenia nowych kryteriów.

  18. Cold Fusion Has Now Come Out of the Cold

    Science.gov (United States)

    Storms, Edmund

    2003-10-01

    The phenomenon called cold fusion or LENR (Low-Energy-Nuclear-Reaction) has now achieved a level of reproducibility and understanding that warrants re-examination of the claims. A summary of what is known and want is being done worldwide to obtain more knowledge will be given. Rather than disappearing as better data are obtained, the effects are becoming more reproducible and of greater magnitude. Justification for this claim can be obtained at www.LENR-CANR.org. The phenomenon is too important to ignore any longer even though it conflicts with conventional theory.

  19. Discovery Café Now Offers Online Ordering for Catering | Poster

    Science.gov (United States)

    If you need to have a breakfast or lunch event/meeting catered, look no further than the Discovery Café in Building 549. You can now place catering orders online for groups of five or more. The café will provide catering services for events or meetings held onsite, as well as those held at the Advanced Technology Research Facility. Orders are delivered to the site of the event

  20. Clean Cities Now, Vol. 13, No. 2 - June 2009 (Brochure)

    Energy Technology Data Exchange (ETDEWEB)

    2009-06-01

    The June 2009 issue of Clean Cities Now features stories about elementary school students establishing no-idle zones in San Antonio; recent Propane Road Shows in Virginia, Maryland, and South Carolina; green vehicles helping children's charities in California; and a new truck stop electrification system in South Carolina. The Fleet Experiences story features the University of Illinois-Chicago's mixed fleet of alternative fuel vehicles.

  1. KubeNow: A Cloud Agnostic Platform for Microservice-Oriented Applications

    OpenAIRE

    Capuccini, Marco; Larsson, Anders; Toor, Salman; Spjuth, Ola

    2018-01-01

    KubeNow is a platform for rapid and continuous deployment of microservice-based applications over cloud infrastructure. Within the field of software engineering, the microservice-based architecture is a methodology in which complex applications are divided into smaller, more narrow services. These services are independently deployable and compatible with each other like building blocks. These blocks can be combined in multiple ways, according to specific use cases. Microservices are designed ...

  2. Nuclear power now and in the future

    Energy Technology Data Exchange (ETDEWEB)

    Collier, J G [Nuclear Electric (United Kingdom)

    1991-08-01

    The future of the nuclear industry in the United Kingdom is considered from the perspective of the new public sector utility, Nuclear Electric, set up to retain control of nuclear power stations on the privatization of the rest of the electricity supply industry. Two major objectives are the increased nuclear generation of electricity and the cutting of costs. These are discussed in terms of life extension programmes for the magnox reactors, improved performance of AGR reactors and expectations for the Sizewell B PWR station now under construction; waste management, reactor decommissioning and fuel-cycle costs are also considered. Economic, environmental and political criteria are outlined which need to be addressed in relation to the government's review of nuclear power in 1991. Because of the marginal economic advantages of nuclear power in the United Kingdom, it will be important to quantify the environmental and diversity benefits of this source. (UK).

  3. Farmer's lung is now in decline.

    LENUS (Irish Health Repository)

    Arya, A

    2012-02-03

    Farmer\\'s lung incidence in Ireland was constant until 1996, even though hay making methods were revolutionised in late 1980\\'s. We undertook this study to find out the incidence of farmer\\'s lung in Ireland from 1982-2002 and its correlation with rainfall and the effect of changing farm practices. The primary cases of farmer\\'s lung were identified from Hospital in Patients Enquiry (HIPE) unit of the national Economic & Social Research Institute (ESRI) Dublin. Rainfall data were obtained from Met Eireann whereas population, hay production and silage production were obtained from the Central Statistics Office, Dublin. As the farming population is in decline, we used the annual working unit (AWU), which reflects the true population at risk. An AWU is the equivalent of 1800 hours per farm worker per year. The incidence rates were constant from 1982-1996, but from 1997-2002 a marked decline was observed. There was strong positive correlation with hay production (r = 0.81) and strong negative correlation with silage production (r = -0.82). This study indicates that the incidence of farmer\\'s lung is now in decline.

  4. kNOw Fear: Making rural public spaces safer for women and girls ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2018-05-01

    May 1, 2018 ... kNOw Fear: Making rural public spaces safer for women and girls ... The International Centre for Research on Women (ICRW) conducts research ... Poonam Kathuria's 17 years of experience as a women's rights advocate is ...

  5. Red giants: then and now

    Science.gov (United States)

    Faulkner, John

    Fred Hoyle's work on the structure and evolution of red giants, particularly his pathbreaking contribution with Martin Schwarzschild (Hoyle and Schwarzschild 1955), is both lauded and critically assessed. In his later lectures and work with students in the early 1960s, Hoyle presented more physical ways of understanding some of the approximations used, and results obtained, in that seminal paper. Although later ideas by other investigators will be touched upon, Hoyle's viewpoint - that low-mass red giants are essentially white dwarfs with a serious mass-storage problem - is still extremely fruitful. Over the years, I have further developed his method of attack. Relatively recently, I have been able to deepen and broaden the approach, finally extending the theory to provide a unifying treatment of the structure of low-mass stars from the main sequence though both the red-giant and horizontal-branch phases of evolution. Many aspects of these stars that had remained puzzling, even mysterious, for decades have now fallen into place, and some questions have been answered that were not even posed before. With low-mass red giants as the simplest example, this recent work emphasizes that stars, in general, may have at least two distinct but very important centres: (I) a geometrical centre, and (II) a separate nuclear centre, residing in a shell outside a zero-luminosity dense core for example. This two-centre perspective leads to an explicit, analytical, asymptotic theory of low-mass red-giant structure. It enables one to appreciate that the problem of understanding why such stars become red giants is one of anticipating a remarkable yet natural structural bifurcation that occurs in them. This bifurcation occurs because of a combination of known and understandable facts just summarized namely that, following central hydrogen exhaustion, a thin nuclear-burning shell does develop outside a more-or-less dense core. In the resulting theory, both ρsh/ρolinec and

  6. With State Support Now Tied to Completion, Tennessee Colleges Must Refocus

    Science.gov (United States)

    Kelderman, Eric

    2012-01-01

    Before last year, public colleges in Tennessee had a very good reason to fill classroom seats through the first couple of weeks of the term. Each institution's share of the state appropriations for higher education was largely based on enrollment at that point in the semester. Now, however, those colleges stand to lose state money if students do…

  7. "Pay Now, Argue Later" Rule – Before and After the Tax ...

    African Journals Online (AJOL)

    The South African Revenue Service (SARS) is entrusted with the duty of collecting tax on behalf of the South African government. In order to ensure effective and prompt collection of taxes, the payment of tax is not suspended pending an objection or an appeal, unless directed otherwise. This is also known as the "pay now, ...

  8. Now calling at the International Space Station

    CERN Document Server

    Katarina Anthony

    2012-01-01

    On 31 July, an unmanned Russian Progress spacecraft was launched from the desert steppe of Kazakhstan. Its destination: the International Space Station (ISS). On board: five Timepix detectors developed by the Medipix2 Collaboration.   With the Timepix on board, Progress 48 was launched 31 July from the Baikonur Cosmodrome in Kazakhstan. Source: RSC Energia. Timepix detectors are small, USB powered particle trackers based on Medipix2 technology. The Timepix chip, which was developed at CERN, is coupled to a silicon sensor and incorporated into a minature readout system - developed at IEAP, Prague - which is about the size of a USB pen drive. These systems have been used across a variety of disciplines: from the study of cosmic rays to biomedical imaging. Now on board the ISS, they are providing highly accurate measurements of space radiation for dosimetry purposes. “There’s nothing else in the world that has quite the capability of Timepix detectors to ...

  9. Personal, Informal and Relatable: Engaging Wide Audiences in Climate Science with Nasa's Earth Right Now Blog

    Science.gov (United States)

    Tenenbaum, L. F.; Shaftel, H.; Jackson, R.

    2014-12-01

    There is no such thing as a non-scientist, but there are some who have yet to acknowledge their inner science spark. Aiming to ignite and fan the flame of curiosity, promote dialogue and attempt to make climate science personal and relevant to everyday life, NASA's Global Climate Change website http://climate.nasa.gov/ and Earth Right Now campaign http://www.nasa.gov/content/earth-right-now/ partnered together this year to launch the Earth Right Now blog http://climate.nasa.gov/blog. It quickly became one of the most popular blogs in all of NASA social media, receiving thousands of likes per week, and frequent comments as well as thoughtful and respectful discussions about climate change. Social media platforms such as blogs have become popular vehicles for engaging large swaths of the public in new exciting ways. NASA's Earth Right Now blog has become a powerful platform for engaging both scientists and the science-curious in constructive, fruitful conversations about the complex topic of climate science. We continue to interact and have ongoing dialogue with our readers by making the scientific content both accessible and engaging for diverse populations.

  10. 'Teraz' u Parminidesa: B 8.5 ('NOW' ACCORDING TO PARMENIDES: B 8.5

    Directory of Open Access Journals (Sweden)

    Jerzy Pawliszcze

    2008-06-01

    Full Text Available The main purpose of this paper is to analyze the concept of time in Parmenides' poem. The author begins with comparison between Parmenides and the concept of eternity in Plato's Timaeus. Some historian agree, that concept of eternity was alien for Parmenides and argue from fragm. 8, 5-6, where Parmenides uses the term 'now' - nyn in non-eternal sense. The author reads the conceptions of Schofield, Kahn, Gallop and Groarke (and many other writers and observe some difficulties with their interpretations. He makes entrance with strictly philological analysis of nyn (Plato, Sophocles, Aristotle and compares their use of 'now' with poems of Pindar. The author introduces the concept of 'cyclical' time, where order of moments is irrelevant and men can achieve salvation relatively easy to access.

  11. Developing Collections With Get It Now: A Pilot Project for a Hybrid Collection.

    Science.gov (United States)

    Hendler, Gail Y; Gudenas, Jean

    2016-01-01

    As health sciences libraries transition from print to online journal collections that require significant institutional funding, librarians are investigating the use of on demand services in order to meet customer need and contain costs. In 2014 a three-year pilot project to determine if unmediated access to the Copyright Clearance Center's Get It Now service would expand access to needed content and provide usage data to inform collections decision making. The service provides rapid, automated delivery of unsubscribed, high-quality journal articles directly to the customer. The three-year pilot project aims to compare the cost of Get It Now to the traditional subscription model to learn if the service is a cost-effective and sustainable alternative that improves customer satisfaction and that can transform collection development with a hybrid model for journal acquisitions.

  12. Effects of Practice Type in the Here and Now Mobile Learning Environment

    Science.gov (United States)

    Tutty, Jeremy I.; Martin, Florence

    2014-01-01

    This generation of technology is characterized by mobile and portable devices such as smartphones and tablet computers with wireless broadband access. Mobile technologies enable a new kind of learning called "here and now learning," where learners have access to information anytime and anywhere to perform authentic activities in the…

  13. What criteria should now be applied in energy resource planning

    International Nuclear Information System (INIS)

    Puechl, K.H.

    1976-01-01

    Twenty years ago decisions on nuclear power were made on purely economic grounds. Little attention was given to public acceptability, broad-scope cost/benefit analysis, environmental impacts, or conservation of resources. In the light of the significantly different situation that exists today, were the proper decisions made, and what should now be the basis for proper comparable analysis. Acknowledging that energy resource planning is extremely complex, a logical approach is suggested that provides a more meaningful basis for public choice and decision-making. (author)

  14. 3,700 USAF Junior Acquisition Officers! Rebalance USAF Manning Priorities Now

    Science.gov (United States)

    2017-04-06

    the benefits of the AD LAF acquisition officer direct accessions is not worth the initial resource costs and return on investment relative to higher...government funding spurred significant technology development; today, that trend has shifted: commercial investment now propels the preponderance of ground...many companies on selling to the commercial market .”45 DoD Directive (DoDD) 5105.85, signed by former Secretary of Defense Ash Carter on 5 July

  15. Ivory Arches and Golden Towers: Why We're All Consumer Researchers Now.

    Science.gov (United States)

    Wehner, Pat

    2001-01-01

    Considers how enterprising marketers quickly realized they had little to lose by supporting a goal of equal "representation." Suggests that if the goal is to have a genuine impact in playing the popular culture game, now might be a prudent moment to take an interest in the kinds of research emerging from business schools. (SG)

  16. Revolution…Now The Future Arrives for Five Clean Energy Technologies – 2015 Update

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-11-01

    In 2013, the U.S. Department of Energy (DOE) released the Revolution Now report, highlighting four transformational technologies: land-based wind power, silicon photovoltaic (PV) solar modules, light-emitting diodes (LEDs), and electric vehicles (EVs). That study and its 2014 update showed how dramatic reductions in cost are driving a surge in consumer, industrial, and commercial adoption for these clean energy technologies—as well as yearly progress. In addition to presenting the continued progress made over the last year in these areas, this year’s update goes further. Two separate sections now cover large, central, utility-scale PV plants and smaller, rooftop, distributed PV systems to highlight how both have achieved significant deployment nationwide, and have done so through different innovations, such as easier access to capital for utility-scale PV and reductions of non-hardware costs and third-party ownership for distributed PV. Along with these core technologies

  17. Zasoby bibliotek francuskich – organizacja, zarządzanie, potencjał ludzki, nowe media

    Directory of Open Access Journals (Sweden)

    Stachnik Maria

    2015-12-01

    Full Text Available Artykuł stanowi próbę prezentacji francuskich bibliotek w kontekście usytuowania ich w strukturach państwa, a także pokazania prawnych i finansowych determinantów ich działalności. Przedstawia zasoby ludzkie czyli bibliotekarzy, ich ścieżkę edukacyjną, sposoby zdobywania wiedzy i kwalifikacji, jakie muszą posiadać, aby pracować w różnych typach bibliotek we Francji. Omówiono także nowe sposoby dzielenia się wiedzą poprzez nowoczesne technologie informatyczne i informacyjno-komunikacyjne. Z tej perspektywy biblioteki (postrzegane jako miejsca gromadzenia, zdobywania i udostępniania wiedzy zaprezentowano jako instytucje otwierające nowe możliwości przed pracownikami oraz użytkownikami, które dzięki nowym mediom, ich właściwościom, mogą być łatwo przez wszystkich wykorzystywane do szeroko rozumianej komunikacji bez ograniczeń czasowych i przestrzennych.

  18. TADDM – SERVICENOW- INTEGRAATIO : Palvelinten välisten relaatiotietojen siirtäminen TADDM-ohjelmasta ServiceNow-alustaan

    OpenAIRE

    Silfsten, Rene

    2015-01-01

    Opinnäytetyössä tehtiin integraatio IBM:n Tivoli Application Dependency Discovery Manager -konfiguraationhallintaohjelman ja ServiceNow-palvelunhallinta-alustan välille. IBM:n TADDM-ohjelmasta siirrettiin ServiceNow-alustaan palvelinten väliset relaatiotiedot. Työ tehtiin Enfo Oyj:lle yrityksessä käynnissä olleen ”Konfi-guraation- ja muutoksenhallinnan työkalu–POC (TADDM)” –nimisen projektin yhteydessä. Työ aloitettiin perehtymällä sekä palvelunhallintaan että konfiguraationhallintaan ...

  19. [Enteral alimentation at home: why PEG now?].

    Science.gov (United States)

    Suzuki, Y; Hanyu, N; Kashiwagi, H; Kubo, T; Aoki, T

    1996-12-01

    The history of percutaneous endoscopic gastrostomy (PEG) is relatively short. In 1980, a report entitled "Gastrostomy without laparotomy: A percutaneous endoscopic technique" by Ponsky and Gaudere was first published in the Journal of Pediatric Surgery. Thereafter, PEG soon saw widespread use in Western countries because of its clinical efficacy and economy. It has been performed in about 170,000 cases annually in the US. In contrast, its spread in Japan has been extremely slow: only about 10,000 cases have undergone this procedure annually, and this number accounted for less than 5% of patients receiving enteral alimentation. The reason why PEG has not spread may be the medical insurance system in Japan and the local distaste for operation scarring. However, in consideration of the unprecedented ageing of society that is surely coming in the near future, the role of PEG in Japan must be reexamined. In this report, we presented the methodology of enteral alimentation at home by means of PEG, giving special consideration to: (1) "What points are improved by using enteral alimentation at home by means of PEG in various diseases; (2) dysphagia due to cerebral angiopathy; (3) terminal cancer; (4) otolaryngological diseases; and (5) Crohn disease. We also discussed "Why PEG is important now?" in performing enteral alimentation at home.

  20. New…Now?: Or Why a Design History of Coin-Op Video Game Machines

    Science.gov (United States)

    Guins, Raiford

    2017-01-01

    The author asks what has occurred in game history scholarship to warrant the use of the adjective "new" in "New Video Game History" and suggests an awareness of process may now be influencing the study of games. In support of this observation, he organizes the article along two interrelated fronts. The first speaks to the…

  1. Enhanced recovery after elective colorectal surgery: now the standard of care.

    LENUS (Irish Health Repository)

    Andrews, E J

    2011-09-01

    Enhanced recovery programmes have been studied in randomised trials with evidence of quicker recovery of gut function, reduced morbidity, mortality and hospital stay and improved physiological and nutritional outcomes. They aim to reduce the physiological and psychological stress of surgery and consequently the uncontrolled stress response. The key elements, reduced pre-operative fasting, intravenous fluid restriction and early feeding after surgery, are in conflict with traditional management plans but are supported by strong clinical evidence. Given the strength of the current data enhanced recovery should now be the standard of care.

  2. CMS Create #2 | 3-4 October | Register now!

    CERN Multimedia

    2016-01-01

    CMS Create brings together CERN members and students from IPAC Design Genève (see here). The goal is to build a prototype exhibit illustrating what CMS does and how it does it. The exhibit will introduce the world of a particle physics detector to the general public, and to younger visitors in particular.    CMS Create, hosted by IdeaSquare, was first held in November 2015. There were 4 highly diverse teams made of participants from many educational backgrounds and from 15 nationalities. 36% of these were women; a figure we hope will grow this year. The 25 participants were CMS physicists, computer scientists, engineers, other CMS collaborators and IPAC students. The 2015 winning exhibit is now permanently installed in the visitor reception centre at CMS Point 5, which was visited by 20.600 visitors during 2015. Are you creative and motivated to share your ideas?  Take part in CMS Create #2, meet with scientists and designers from all over the world and explain to CER...

  3. Teaching History Then and Now: A Story of Stability and Change in Schools

    Science.gov (United States)

    Cuban, Larry

    2016-01-01

    In "Teaching History Then and Now," Larry Cuban explores the teaching of history in American high schools during the past half-century. Drawing on his early career experience as a high school history educator and his more recent work as a historian of US education policy and practice, Cuban examines how determined reformers have and have…

  4. 20 CFR 404.1595 - When we determine that you are not now disabled.

    Science.gov (United States)

    2010-04-01

    ... Disability § 404.1595 When we determine that you are not now disabled. (a) When we will give you advance... your Social Security number and do not live with you, we will also give them advance notice. To give you advance notice, we will contact you by mail, telephone or in person. (b) What the advance notice...

  5. Evolving RNA Virus Pandemics: HIV, HCV, Ebola, Dengue, Chikunguya, and now Zika!

    Science.gov (United States)

    Barreiro, Pablo

    2016-01-01

    The Zika virus (ZIKV), a flavivirus related to yellow fever, dengue, and West Nile, originated in the Zika forest in Uganda and was discovered in a rhesus monkey in 1947. The disease now has "explosive" pandemic potential, with outbreaks in Africa, Southeast Asia, the Pacific Islands, and the Americas. To date, the CDC has issued travel alerts for at least 30 countries and territories in Latin America, the Caribbean, Polynesia, and Cape Verde in Africa.

  6. "PAY NOW, ARGUE LATER" RULE – BEFORE AND AFTER THE TAX ADMINISTRATION ACT

    Directory of Open Access Journals (Sweden)

    Carika Keulder

    2013-12-01

    Full Text Available The South African Revenue Service (SARS is entrusted with the duty of collecting tax on behalf of the South African government. In order to ensure effective and prompt collection of taxes, the payment of tax is not suspended pending an objection or an appeal, unless directed otherwise. This is also known as the "pay now, argue later" rule, and, for value-added tax purposes, is provided for in terms of section 36 of the Value-Added Tax Act 89 of 1991. The "pay now, argue later" rule in terms of section 36 of the Value-Added Tax Act prima facie infringes on a taxpayer's right of access to the courts as envisaged in section 34 of the Constitution. This is due to the fact that a taxpayer is obliged to pay tax before being afforded the opportunity to challenge the assessment in a court. In Metcash Trading Ltd v Commissioner for the South African Revenue Service, the Constitutional Court held the "pay now, argue later" rule in terms of section 36 to be constitutional. Olivier, however, does not agree with the court on several matters. Amongst the problems she indicates are that the taxpayer does not have access to the courts at the time the rule is invoked, and that the court did not consider the fact that there might be less invasive means available which would ensure that SARS's duty is balanced with the taxpayer's right of access to the courts. Guidelines were also issued which provide legal certainty regarding the factors SARS may consider in determining whether the payment of tax should be suspended or not. These guidelines also evoked some points of criticism. Since 1 October 2012, the "pay now, argue later" rule has been applied in terms of section 164 of the Tax Administration Act 28 of 2011. The question arises whether this provision addresses the problems identified in respect of section 36 of the Value-Added Tax Act and the guidelines. In comparing these sections, only slight differences emerged. The most significant difference is that

  7. The Millimeter Wave Observatory antenna now at INAOE-Mexico

    Science.gov (United States)

    Luna, A.

    2017-07-01

    The antenna of 5 meters in diameter of the legendary "Millimeter Wave Observatory" is now installed in the INAOE-Mexico. This historic antenna was reinstalled and was equipped with a control system and basic primary focus receivers that enabled it in teaching activities. We work on the characterization of its surface and on the development of receivers and spectrometers to allow it to do research Solar and astronomical masers. The historical contributions of this antenna to science and technology in radio astronomy, serve as the guiding force and the inspiration of the students and technicians of our postgrade in Astrophysics. It is enough to remember that it was with this antenna, that the first molecular outflow was discovered, several lines of molecular emission were discovered and it was the first antenna whose surface was characterized by holography; among many other technological and scientific contributions.

  8. AirNow Information Management System - Global Earth Observation System of Systems Data Processor for Real-Time Air Quality Data Products

    Science.gov (United States)

    Haderman, M.; Dye, T. S.; White, J. E.; Dickerson, P.; Pasch, A. N.; Miller, D. S.; Chan, A. C.

    2012-12-01

    Built upon the success of the U.S. Environmental Protection Agency's (EPA) AirNow program (www.AirNow.gov), the AirNow-International (AirNow-I) system contains an enhanced suite of software programs that process and quality control real-time air quality and environmental data and distribute customized maps, files, and data feeds. The goals of the AirNow-I program are similar to those of the successful U.S. program and include fostering the exchange of environmental data; making advances in air quality knowledge and applications; and building a community of people, organizations, and decision makers in environmental management. In 2010, Shanghai became the first city in China to run this state-of-the-art air quality data management and notification system. AirNow-I consists of a suite of modules (software programs and schedulers) centered on a database. One such module is the Information Management System (IMS), which can automatically produce maps and other data products through the use of GIS software to provide the most current air quality information to the public. Developed with Global Earth Observation System of Systems (GEOSS) interoperability in mind, IMS is based on non-proprietary standards, with preference to formal international standards. The system depends on data and information providers accepting and implementing a set of interoperability arrangements, including technical specifications for collecting, processing, storing, and disseminating shared data, metadata, and products. In particular, the specifications include standards for service-oriented architecture and web-based interfaces, such as a web mapping service (WMS), web coverage service (WCS), web feature service (WFS), sensor web services, and Really Simple Syndication (RSS) feeds. IMS is flexible, open, redundant, and modular. It also allows the merging of data grids to create complex grids that show comprehensive air quality conditions. For example, the AirNow Satellite Data Processor

  9. Power for southern Italy: hvdc Sardinia to mainland 200 MW scheme now commissioned

    Energy Technology Data Exchange (ETDEWEB)

    1967-02-16

    Transmission of the maximum rated power of 200 MW over the hvdc system which now links Sardinia with the Italian Mainland marks the successful completion of a notable British Export contract by English Electric. The link was commissioned on February 1. The Sardinia scheme is the seventh hvdc scheme to be completed in the world and is the first to be engineered by submarine cable.

  10. A road long travelled: is SCOAP 3 now arriving?

    Directory of Open Access Journals (Sweden)

    Ralf Schimmer

    2013-07-01

    Full Text Available The relatively small and specialized international scholarly community of high energy physics (HEP is leading the way to the ‘gold’ model of open access (OA. With the leadership and substantial support of CERN, the community's Geneva-based hub, the Sponsoring Consortium for Open Access Publishing in Particle Physics (SCOAP3 has created an innovative model for OA publishing. Whereas the journal subscriptions of today implicitly support the important process of peer review, the new model federates funding agencies and libraries to cover journals' professional publication costs explicitly, while publishers make the electronic versions of their journals free to read. Authors are not directly charged to publish their articles OA. Each SCOAP3 partner will finance its contribution by canceling journal subscriptions, and each country will contribute according to its share of HEP publishing. The project is now embarked on a complex finessing process on the route to the projected 2014 launch.

  11. Moving down the Track: Changing School Practices during the Second Year of "Diplomas Now"

    Science.gov (United States)

    Sepanik, Susan; Corrin, William; Roy, David; Gray, Aracelis; Fernandez, Felix; Briggs, Ashley; Wang, Kathleen K.

    2015-01-01

    Too many students in high-poverty, urban communities drop out of high school, and too few graduate prepared for college and careers. Three national organizations--Talent Development Secondary, City Year, and Communities In Schools--have formed "Diplomas Now" in an effort to transform urban secondary schools so fewer students drop out and…

  12. Institutional open access funds: now is the time.

    Science.gov (United States)

    Eckman, Charles D; Weil, Beth T

    2010-05-25

    To date, the Berkeley OA fund has ensured that 43 articles are free to be read immediately upon publication and 44 additional articles are now in the pipeline. The full scope of OA publishing during this period was significantly larger, at least by a factor of four. The OA fund allocation will continue to be carefully managed over the coming years. We are tracking our potential liability assuming the OA landscape grows with additional publishers and OA options. The amount predicted as necessary to maintain the fund based on the initial 18-month uptake data is US$45,000. This is less than 1% of the US$6.2 million the library invests in subscribing to closed-access digital journals. We are paying attention in particular to the attempts by the California Digital Library, which negotiates major journal publisher licenses on behalf of the UC campuses, to include terms within the licenses that enable UC authors to take advantage of publishers'hybrid OA options [16]. And it comes with far less of the myriad overhead costs associated with those closed-access subscriptions because that subscription price doesn't tell the full story of the actual cost of maintaining the subscription. Those subscriptions involve staff-intensive license negotiations. Institutions develop and maintain systems architectures in order to ensure that only authorized users have access and respond to challenges from publishers of the content when actual or potential breaches of the licenses are identified (publishers invest hugely in monitoring use of their content in order to ensure the license terms are not breached and are quite willing to contact the institutional subscriber when any untoward activity appears on their logs). They must, in certain instances, maintain the confidentiality of certain clauses in the licenses and increasingly respond to freedom of information, public records act requests related to the investments of public resources in those contracts. The need to experiment is

  13. Assessing the ecological status in the context of the European Water Framework Directive: where should we go now?

    OpenAIRE

    REYJOL Yorick; ARGILLIER Christine; BONNE Wendy; BORJA Angel; BUIJSE Tom; CARDOSO Ana; DAUFRESNE Martin; KERNAN Martin; FERREIRA Maria; POIKANE Sandra; PRAT Narcis; Solheim Anne Lyche; STROFFEK Stefan; USSEGLIO-POLATERA Philippe; VILLENEUVE Bertrand

    2014-01-01

    After more than a decade of implementation by water managers in all river basins across Europe, the Water Framework Directive (WFD) has now reached a maturity age. However, some significant gaps still remain in the way WFD is implemented, and there is now a need for water managers and scientist to communicate better in order to find scientific solutions to these gaps. To do so, a Science-Policy Interface (SPI) activity was launched in 2010 led by Directorate General (DG) Research and Onema (t...

  14. "To Kill A Mockingbird": Then and Now--A 35th Anniversary Celebration. Teacher Study Guide.

    Science.gov (United States)

    National Council of Teachers of English, Urbana, IL.

    This study guide offers a different approach, teleconferencing, to new information, ideas, and resources on the film, "To Kill a Mockingbird." Following general information on "then and now," the guide consists of sections entitled: Preparing to Teach TKM: Special Considerations (by Charles Suhor and Larry Bell); Historical…

  15. Love in the Time of Facebook: How Technology Now Shapes Romantic Attachments in College Students

    Science.gov (United States)

    Klein, Michael C.

    2013-01-01

    College counseling clinicians need to understand how students use technology to form, sustain, and end romantic attachments. Students now frequently incorporate aspects of these technologically based interactions, or mediated communications, into counseling sessions and often make important attributions based on them. Heavy daily use of a growing…

  16. "Now Art Now Future" Leedus

    Index Scriptorium Estoniae

    2005-01-01

    Seitse näitust Baltimaade graafikast Vilniuses, Kaunases ja Klaipedas. Eestist osalesid P. Allik, I. Heamägi, L. Jõekalda, A. Kalm, M. Nukke, L. Ruben, M.-K. Ulas, S. Tamsalu, A. Vahtrapuu, K. Valk. Eesti kuraatorid M.-K. Ulas ja V. Thurlow

  17. Now playing in a browser near you: TEDxCERN

    CERN Multimedia

    Katarina Anthony

    2013-01-01

    Earlier this month, CERN played host to one of the hottest, hippest and most educational parties around: TEDx. The event brought together thousands of viewers, speakers and participants from around the world.   The TEDxCERN event was the hottest ticket in town – and those who couldn’t make the event in person turned up online! More than 1,000 TEDxCERN fans watched the event via simulcast at viewing parties held in 27 institutions, but dominating the audience were the 10,870 unique viewers who tuned in to the live webcast, along with over 300 people who joined the webcast from CERN and another 300 watching it live from the Globe of Science and Innovation at CERN. But if you missed the excitement, never fear. Videos of the talks, as well as the clips presented during the talks themselves, are now available online. Just head to the TEDxCERN homepage and catch up! Watch as researcher Maya Tolstoy discusses seafloor earthquakes, Google Science Fair winner Brittany Wengler ...

  18. Do e-mail alerts of new research increase knowledge translation? A "Nephrology Now" randomized control trial.

    Science.gov (United States)

    Tanna, Gemini V; Sood, Manish M; Schiff, Jeffrey; Schwartz, Daniel; Naimark, David M

    2011-01-01

    As the volume of medical literature increases exponentially, maintaining current clinical practice is becoming more difficult. Multiple, Internet-based journal clubs and alert services have recently emerged. The purpose of this study is to determine whether the use of the e-mail alert service, Nephrology Now, increases knowledge translation regarding current nephrology literature. Nephrology Now is a nonprofit, monthly e-mail alert service that highlights clinically relevant articles in nephrology. In 2007-2008, the authors randomized 1,683 subscribers into two different groups receiving select intervention articles, and then they used an online survey to assess both groups on their familiarity with the articles and their acquisition of knowledge. Of the randomized subscribers, 803 (47.7%) completed surveys, and the two groups had a similar number of responses (401 and 402, respectively). The authors noted no differences in baseline characteristics between the two groups. Familiarity increased as a result of the Nephrology Now alerts (0.23 ± 0.087 units on a familiarity scale; 95% confidence interval [CI]: 0.06-0.41; P = .007) especially in physicians (multivariate odds ratio 1.83; P = .0002). No detectable improvement in knowledge occurred (0.03 ± 0.083 units on a knowledge scale; 95% CI: -0.13 to 0.20; P = .687). An e-mail alert service of new literature improved a component of knowledge translation--familiarity--but not knowledge acquisition in a large, randomized, international population.

  19. SeisComP 3 - Where are we now?

    Science.gov (United States)

    Saul, Joachim; Becker, Jan; Hanka, Winfried; Heinloo, Andres; Weber, Bernd

    2010-05-01

    The seismological software SeisComP has evolved within the last approximately 10 years from a pure acquisition modules to a fully featured real-time earthquake monitoring software. The now very popular SeedLink protocol for seismic data transmission has been the core of SeisComP from the very beginning. Later additions included simple, purely automatic event detection, location and magnitude determination capabilities. Especially within the development of the 3rd-generation SeisComP, also known as "SeisComP 3", automatic processing capabilities have been augmented by graphical user interfaces for vizualization, rapid event review and quality control. Communication between the modules is achieved using a a TCP/IP infrastructure that allows distributed computing and remote review. For seismological metadata exchange export/import to/from QuakeML is avalable, which also provides a convenient interface with 3rd-party software. SeisComP is the primary seismological processing software at the GFZ Potsdam. It has also been in use for years in numerous seismic networks in Europe and, more recently, has been adopted as primary monitoring software by several tsunami warning centers around the Indian Ocean. In our presentation we describe the current status of development as well as future plans. We illustrate its possibilities by discussing different use cases for global and regional real-time earthquake monitoring and tsunami warning.

  20. Lean Now-Using a Research Community to Understand Change in the Aquisition Enterprise (Defense Acquisition Review Journal)

    National Research Council Canada - National Science Library

    2004-01-01

    Members of the Lean Aerospace Initiative (LAI) consortium have joined to pool experience and expertise to accelerate the adoption of Lean practices in military acquisition through an initiative called Lean Now...

  1. Al principio, el fin: “The End” en el preludio de Apocalypse Now

    OpenAIRE

    García Escrivá, Vicente

    2014-01-01

    El desarrollo creativo de Apocalypse Now (Francis Ford Coppola, 1979) estuvo caracterizado por una revisión constante del guión, un rodaje anormalmente extenso y accidentado y una postproducción muy laboriosa y en absoluto convencional. Todo ello propició una marcada metamorfosis respecto del proyecto original de John Milius, inicialmente sustentado en la novela El corazón de las tinieblas de Joseph Conrad y en una serie de ingredientes bélicos tratados desde un prisma psicodélico (Cowie, 200...

  2. PGE decides to close plant now, not in 1996

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    On January 4, two months and a day after the Trojan nuclear power reactor survived two ballot initiatives that sought to have the 1095-MWe pressurized water reactor closed immediately, the board of directors of Portland General Electric Company voted to do what those initiatives had wanted done. Trojan went off line on November 9 because of a leak in a steam generator tube. It will not return to service ever again, even though PGE had originally planned to keep running the plant until 1996. The utility announced that immediate closure was now the least-cost choice for ratepayers, mainly because of uncertainty over what would have to be done at the plant to satisfy the Nuclear Regulatory Commission - within which, according to PGE, there was a scientific disagreement over the adequacy of the plant's steam generators to support operation until 1996. PGE has not yet firmed up its decommissioning plan for Trojan. Also, at this writing, there had been no indication whether the absence of Trojan might improve the chances for completion of the region's two mothballed nuclear projects, Washington Public Power Supply System's WNP-1 and -3

  3. Now Enhancing Working Skills: The ``NEWS`` Program. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Kuiper, A. [Merex Corp. (United States)

    1995-01-23

    In October of 1992, Los Alamos National Laboratory and Merex Corporation began a pilot basic skills program to enhance workers` skills. The program, known as the NEWS (Now Enhancing Working Skills) Program, was implemented by the Training and Development Group of the Human Resources Division. A group of 106 employees known as Radiological Control Technicians (RCTs) from ESH-1 (Environmental, Safety, and Health) were targeted to take mandated DOE (Department of Energy) training. The main goal of the LANL/Merex partnership was to help RCTs prepare for mandated DOE Rad Con training and job performance by improving their information processing and math skills. A second goal of this project was to use the information from this small group to make some predictions about the Laboratory as a whole. This final report contains the description and an appendix for the ``NEWS`` program. The topics in this report include Merex class descriptions, test score results for the MAT, the WAT, the TABE, and Challenge test, a follow-up survey to Merex IPS and math training, student feedback statistics for skills programs, and lessons learned from the program.

  4. Progressive Presentations of Place-Based Identities in Meg Rosoff's "How I Live Now"

    Science.gov (United States)

    Lockney, Karen

    2013-01-01

    This article provides a close reading of Meg Rosoff's award-winning novel "How I Live Now". It argues that an understanding of the text can be extended through an application of ideas found in contemporary spatial discourse concerning place. Reading the novel within this context allows a discussion of ways in which it draws on…

  5. UID....Now That's Gonna Leave A Mark

    Science.gov (United States)

    Schramm, Harry F., Jr.

    2008-01-01

    Since 1975 bar codes on products at the retail counter have been accepted as the standard for entering product identity for price determination. Since the beginning of the 21 st century, the Data Matrix symbol has become accepted as the bar code format that is marked directly on a part, assembly or product that is durable enough to identify that item for its lifetime. NASA began the studies for direct part marking Data Matrix symbols on parts during the Return to Flight activities after the Challenger Accident. Over the 20 year period that has elapsed since Challenger, a mountain of studies, analyses and focused problem solutions developed by and for NASA have brought about world changing results. NASA Technical Standard 6002 and NASA Handbook 6003 for Direct Part Marking Data Matrix Symbols on Aerospace Parts have formed the basis for most other standards on part marking internationally. NASA and its commercial partners have developed numerous products and methods that addressed the difficulties of collecting part identification in aerospace operations. These products enabled the marking of Data Matrix symbols in virtually every situation and the reading of symbols at great distances, severe angles, under paint and in the dark without a light. Even unmarkable delicate parts now have a process to apply a chemical mixture, recently trademarked as Nanocodes, that can be converted to Data Matrix information through software. The accompanying intellectual property is protected by ten patents, several of which are licensed. Direct marking Data Matrix on NASA parts dramatically decreases data entry errors and the number of parts that go through their life cycle unmarked, two major threats to sound configuration management and flight safety. NASA is said to only have people and stuff with information connecting them. Data Matrix is one of the most significant improvements since Challenger to the safety and reliability of that connection.

  6. Double beta decay - physics beyond the standard model now, and in future (Genius)

    Energy Technology Data Exchange (ETDEWEB)

    Klapdor-Kleingrothaus, H.V.

    1998-08-01

    Nuclear double beta decay provides an extraordinarily broad potential to search for beyond standard model physics, probing already now the TeV scale, on which new physics should manifest itself. These possibilities are reviewed here. First, the results of present generation experiments are presented. The most sensitive one of them - the Heidelberg-Moscow experiment in the Gran Sasso - probes the electron mass now in the sub eV region and will reach a limit of {proportional_to}0.1 eV in a few years. Basing to a large extent on the theoretical work of the Heidelberg double beta group in the last two years, results are obtained also for SUSY models (R-parity breaking, sneutrino mass), leptoquarks (leptoquark-Higgs coupling), compositeness, right-handed W boson mass and others. These results are comfortably competitive to corresponding results from high-energy accelerators like TEVATRON, HERA, etc. Second, future perspectives of {beta}{beta} research are discussed. A new Heidelberg experimental proposal (GENIUS) is presented which would allow to increase the sensitivity for Majorana neutrino masses from the present level of at best 0.1 eV down to 0.01 or even 0.001 eV. Its physical potential would be a breakthrough into the multi-TeV range for many beyond standard models. Its sensitivity for neutrino oscillation parameters would be larger than of all present terrestrial neutrino oscillation experiments and of those planned for the future. (orig.)

  7. Double beta decay - physics beyond the standard model now, and in future (Genius)

    International Nuclear Information System (INIS)

    Klapdor-Kleingrothaus, H.V.

    1998-01-01

    Nuclear double beta decay provides an extraordinarily broad potential to search for beyond standard model physics, probing already now the TeV scale, on which new physics should manifest itself. These possibilities are reviewed here. First, the results of present generation experiments are presented. The most sensitive one of them - the Heidelberg-Moscow experiment in the Gran Sasso - probes the electron mass now in the sub eV region and will reach a limit of ∝0.1 eV in a few years. Basing to a large extent on the theoretical work of the Heidelberg double beta group in the last two years, results are obtained also for SUSY models (R-parity breaking, sneutrino mass), leptoquarks (leptoquark-Higgs coupling), compositeness, right-handed W boson mass and others. These results are comfortably competitive to corresponding results from high-energy accelerators like TEVATRON, HERA, etc. Second, future perspectives of ββ research are discussed. A new Heidelberg experimental proposal (GENIUS) is presented which would allow to increase the sensitivity for Majorana neutrino masses from the present level of at best 0.1 eV down to 0.01 or even 0.001 eV. Its physical potential would be a breakthrough into the multi-TeV range for many beyond standard models. Its sensitivity for neutrino oscillation parameters would be larger than of all present terrestrial neutrino oscillation experiments and of those planned for the future. (orig.)

  8. Interface of Science, Technology and Security: Areas of Most Concern, Now and Ahead

    Science.gov (United States)

    2017-03-28

    Ph.D. Co-director, Center for International Security and Cooperation, Stanford University Director Emeritus, Los Alamos National Laboratory...either modest, primitive sea-based civilizations, like the Orang Laut of the Malayan peninsula or the Uros of Lake Titicaca in the Andes mountains, or...areas of MosT concern, noW and ahead F Ig U R e 1 C h in a’ s O rg an iz at io n al S tr u ct u re f o r L if e S ci en ce /B io te ch n o lo g

  9. The 2016 Arctic Winter Games: “Now we do what we do best”

    DEFF Research Database (Denmark)

    Ren, Carina Bregnholm; Thomsen, Robert Chr.

    2016-01-01

    A few days before the opening ceremony of the 2016 Arctic Winter Games (AWG) in Nuuk, Greenland, weather reports looked bleak. A spring blizzard was on its way and expected to peak the day prior to the opening ceremony. That very Saturday, 1250 participants were set to fly to Greenland’s capital...... city – the highest number of civilians arriving in one day by aircraft in the island’s history. Now, however, bad weather was jeopardizing this milestone in Greenlandic aviation history and, along with that, the successful execution of the upcoming games....

  10. Prevention of Diabetes With Pioglitazone in ACT NOW

    Science.gov (United States)

    DeFronzo, Ralph A.; Tripathy, Devjit; Schwenke, Dawn C.; Banerji, MaryAnn; Bray, George A.; Buchanan, Thomas A.; Clement, Stephen C.; Gastaldelli, Amalia; Henry, Robert R.; Kitabchi, Abbas E.; Mudaliar, Sunder; Ratner, Robert E.; Stentz, Frankie B.; Musi, Nicolas; Reaven, Peter D.

    2013-01-01

    We examined the metabolic characteristics that attend the development of type 2 diabetes (T2DM) in 441 impaired glucose tolerance (IGT) subjects who participated in the ACT NOW Study and had complete end-of-study metabolic measurements. Subjects were randomized to receive pioglitazone (PGZ; 45 mg/day) or placebo and were observed for a median of 2.4 years. Indices of insulin sensitivity (Matsuda index [MI]), insulin secretion (IS)/insulin resistance (IR; ΔI0–120/ΔG0–120, ΔIS rate [ISR]0–120/ΔG0–120), and β-cell function (ΔI/ΔG × MI and ΔISR/ΔG × MI) were calculated from plasma glucose, insulin, and C-peptide concentrations during oral glucose tolerance tests at baseline and study end. Diabetes developed in 45 placebo-treated vs. 15 PGZ-treated subjects (odds ratio [OR] 0.28 [95% CI 0.15–0.49]; P IGT > T2DM) was associated with improvements in insulin sensitivity (OR 0.61 [95% CI 0.54–0.80]), IS (OR 0.61 [95% CI 0.50–0.75]), and β-cell function (ln IS/IR index and ln ISR/IR index) (OR 0.26 [95% CI 0.19–0.37]; all P < 0.0001). Of the factors measured, improved β-cell function was most closely associated with final glucose tolerance status. PMID:23863810

  11. Books Right Here Right Now at the University of Manchester Library

    Directory of Open Access Journals (Sweden)

    Sarah Rayner

    2016-07-01

    Full Text Available Books Right Here Right Now is a strategic project to radically change core text provision at the University of Manchester. In order to investigate new models for electronic textbook delivery, the project team are running a series of e-textbook pilots, providing textbooks directly to our students via the virtual learning environment. This paper focuses on how usage data and the views of our students and academic staff are underpinning the project in terms of acquisition models, negotiations with publishers and providing a new product to our students. Having detailed the project findings, the article concludes with the authors’ thoughts on the changing environment of the e-textbook market and the various issues within the existing models of e-textbook provision, giving recommendations as to how academic libraries and publishers can help to shape a sustainable model for the UK.

  12. Why finding costs are now a major problem [in the US petroleum industry

    International Nuclear Information System (INIS)

    Gaddis, D.; Brock, H.; Boynton, C.

    1993-01-01

    A major problem facing the US petroleum industry is the higher average finding costs that now exist within the US compared to the average finding costs outside the US. It has been argued that federal lands and offshore areas need to be open for drilling in order to reduce average finding costs in the US. Certainly, the development of a national energy policy must acknowledge the importance of finding costs. Financial analysts for some time have acknowledged the importance of finding costs in evaluating individual energy firms. Analysts expect mergers when it is cheaper for companies to purchase reserves than to find them. Just as industry-average finding costs are a key determinant of long-term market prices for oil and gas, relative finding costs are a key determinant of a company's stock market value. Division managers are now judged regularly by top management on the basis of relative finding costs. The heavy use of finding costs data is causing its own problems, however, because there is as yet no standard for calculating and reporting those costs. This article analyzes the strengths and weaknesses of conventional techniques for determining finding costs. Our goal is a finding costs measure that is a reliable indicator of future profitability. Conceptually, a finding cost figure is a measurement of how much it costs a company to find a barrel of oil or an mcf of gas. The figure is arrived at by dividing the figure for costs incurred during a specified period by the volume (barrels or mcfs) of reserve added during the same period. (author)

  13. ‘Right now, Sophie *swims in the pool?!’: Brain potentials of grammatical aspect processing

    Directory of Open Access Journals (Sweden)

    Monique eFlecken

    2015-11-01

    Full Text Available We investigated whether brain potentials of grammatical aspect processing resemble semantic or morpho-syntactic processing, or whether they instead are characterized by an entirely distinct pattern in the same individuals. We studied aspect from the perspective of agreement between the temporal information in the context (temporal adverbials, e.g., Right now and a morpho-syntactic marker of grammatical aspect (e.g., progressive is swimming. Participants read questions providing a temporal context that was progressive (What is Sophie doing in the pool right now? or habitual (What does Sophie do in the pool every Monday?. Following a lead-in sentence context such as Right now, Sophie…, we measured ERPs time-locked to verb phrases in four different conditions, e.g., (a is swimming (control; (b *is cooking (semantic violation; (c *are swimming (morpho-syntactic violation; or (d?swims (aspect mismatch; …in the pool. The collected ERPs show typical N400 and P600 effects for semantics and morpho-syntax, while aspect processing elicited an Early Negativity (250-350 ms. The aspect-related Negativity was short-lived and had a central scalp distribution with an anterior onset. This differentiates it not only from the semantic N400 effect, but also from the typical (LAN (Left Anterior Negativity, that is frequently reported for various types of agreement processing. Moreover, aspect processing was not accompanied by a clear P600 modulation.We argue that the specific context for each item in this experiment provided a trigger for agreement checking with temporal information encoded on the verb, i.e., morphological aspect marking. The aspect-related Negativity obtained for aspect agreement mismatches reflects a violated expectation concerning verbal inflection (in the example above, the expected verb phrase was Sophie is X-ing rather than Sophie X-s in condition d. The absence of an additional P600 for aspect processing suggests that the mismatch did not

  14. From then to now. Too gentle, too polite, too careful?

    Science.gov (United States)

    Williams, S

    1996-10-01

    Oxfam's Gender and Development Unit (GADU) began in 1985 without scheduled time (all personnel had full-time jobs), premises (whatever space was vacant at the time), or money. David Bryer, incoming overseas director, supported the group and gave it an office and a half-time post. GADU's goal was to raise awareness about gender issues within Oxfam, and to formulate policy for the Overseas Division. What was promoted overseas was to be promoted within Oxfam. GADU cooperated with the Oxfam Women's Group, the Equal Opportunities Working Group, and the Creche Committee (which got the workplace nursery started). Members of GADU steering group included persons from education, campaigns, and all area desks. Members would bring gender issues to the attention of their departments, and GADU would meet regularly to discuss strategies and problems. Colleagues remained surprisingly resistant to ideas current in the development world and suspicious of GADU. Although gender is now on Oxfam's agenda, the struggle continues. Perhaps GADU was born too gently; perhaps "the cotton-wool of Oxfam liberalism" should have been ripped off, and "armed struggle" begun.

  15. Reporting Astronomical Discoveries: Past, Now, and Future

    Science.gov (United States)

    Yamaoka, Hitoshi; Green, Daniel W. E.; Samus, Nikolai N.; West, Richard

    2015-08-01

    Many new astronomical objects have been discovered over the years by amateur astronomers, and this continues to be the case. They have traditionally reported them (as have professional astronomers) to the Central Bureau for Astronomical Telegrams (CBAT), which was established in the 19th century. This procedure has worked very well throughout the 20th century, moving under the umbrella of the newly established IAU in 1920. The discoverers have been honored by the formal announcement of their discoveries in the publications of the CBAT.In recent years, some professional research groups have established other ways of announcing their discoveries of explosive objects such as novae and supernovae; some do not now report their discoveries or spectroscopic confirmations of the transients to the CBAT, including often spectroscopic reports of objects posted to the CBAT "Transient Objects Confirmation Page" -- the highly successful TOCP webpage, which assigns official positional designations to new transients posted there by approved, registered users. This leads to a delay in formal announcements of discoveries by amateur astronomers in many cases, as well as inconsistent designations being put into use by individual groups. Amateur astronomers are feeling frustrated about this situation, and they hope that the IAU will help to settle the situation.We have proposed the new IAU commission NC-52, which will treat these phenomena in a continuation of Commission 6, through the CBAT. We hope to continuously support the reporting of the discoveries by amateur astronomers, as well as professional astronomers, who all deserve and desire proper recognition. Our strategy will maintain the firm trust between the amateur and professional astronomers, which is necessary for true collaboration. The plan is for the CBAT to work with collaborators to assure that discoveries posted on the TOCP are promptly designated and announced by the CBAT, even when confirmations are made elsewhere

  16. 77 FR 16229 - Announcement of Requirements and Registration for the “2012 ASPR Challenge Titled Now Trending...

    Science.gov (United States)

    2012-03-20

    ... data sources. The resulting product from this challenge will cut down on the manpower intensive task of... DEPARTMENT OF HEALTH AND HUMAN SERVICES Announcement of Requirements and Registration for the ``2012 ASPR Challenge Titled Now Trending: Health in My Community'' AGENCY: Office of the Assistant...

  17. Siemens sees a future for IGCC - and now it has the technology

    Energy Technology Data Exchange (ETDEWEB)

    Schmid, C.; Hannemann, F. [Siemens Fuel Gasification Technology, Freiberg (Germany)

    2007-10-15

    About 18 months ago Siemens became a key player in the gasification business through its acquisition of Freiberg based Future Energy and its GSP entrained flow technology, now called SFG (Siemens Fuel Gasification). Developed at Schwarze Pumpe in Eastern Germany over many years, a particular attraction of the process is its ability to use low rank fuels such as lignite, with a robust gasifier wall concept a 'cooling screen' that avoids the use of troublesome refractories. The article explains the SFG gasifier technology. It is ideally suited for coal-fueled IGCC power plants with integrated CO{sub 2} capture, especially for low-rank fuels. SFG has been ordered or pre-selected for a number of projects in China, North America and elsewhere. 5 figs.

  18. Now or never! The effect of deadlines on charitable giving: Evidence from a natural field experiment

    DEFF Research Database (Denmark)

    Damgaard, Mette Trier; Gravert, Christina Annette

    that a reminder increases both the likelihood of making a donation and the amount donated. We find no effect of the deadlines on the propensity to give. Instead we observe a “now-or-never” effect; either donations are made immediately or not at all. In line with the “avoiding-the-ask” theory, both shorter...

  19. Double Beta Decay - Physics Beyond the Standard Model Now, and in Future (GENIUS)

    Science.gov (United States)

    Klapdor-Kleingrothaus, H. V.

    Nuclear double beta decay provides an extraordinarily broad potential to search for beyond Standard Model physics, probing already now the TeV scale, on which new physics should manifest itself. These possibilities are reviewed here. First, the results of present generation experiments are presented. The most sensitive one of them - the Heidelberg-Moscow experiment in the Gran Sasso - probes the electron mass now in the sub eV region and will reach a limit of ˜ 0.1 eV in a few years. Basing to a large extent on the theoretical work of the Heidelberg Double Beta Group in the last two years, results are obtained also for SUSY models (R-parity breaking, sneutrino mass), leptoquarks (leptoquark-Higgs coupling), com-positeness, right-handed W boson mass and others. These results are comfortably competitive to corresponding results from high-energy accelerators like TEVA-TRON, HERA, etc. Second, future perspectives of ʲʲ research are discussed. A new Heidelberg experimental proposal (GENIUS) is presented which would allow to increase the sensitivity for Majorana neutrino masses from the present level of at best 0.1 eV down to 0.01 or even 0.001 eV. Its physical potential would be a breakthrough into the multi-TeV range for many beyond standard models. Its sensitivity for neutrino oscillation parameters would be larger than of all present terrestrial neutrino oscillation experiments and of those planned for the future. It would further, already in a first step, cover almost the full MSSM parameter space for prediction of neutralinos as cold dark matter, making the experiment competitive to LHC in the search for supersymmetry.

  20. From here and now to infinity and eternity: a message to new medical doctors(*).

    Science.gov (United States)

    Lapeña, José Florencio F

    2014-01-01

    Commencement means both an end and a beginning; the end of the academic year and the beginning of the rest of your life as new physicians. For such a beginning, it is useful to view it in retrospect, from the point of view of the end, by conducting a pre-mortem on your life. Taking the existentialist (ex sistere, to stand forth) stance, each of us can be classified into one of four basic types of person, based on our characteristic space and time (or spatio-temporal) context or horizon. Our space can be limited to the "here" and our time to the "now;" or our space may extend to "infinity" and our time embark on "eternity." In-between these poles, most have space contexts rooted in their home and work "turf" and time involving their "lifetime," while some expand their space to include the "world" and their time to encompass "history." From the "here and now" and "turf and lifetime" contexts, the horizons of "world and history," and "infinity and eternity" are examined, challenging new medical doctors to realize their full potential. The new physician is exhorted not to wait for a post-mortem to define (des finitus, to set limits) his or her life. He or she should stand forth, to live, and give life. The new medical doctor is encouraged to look to the sunrise, draw strength from the sunshine, to be brave, and strong and true.

  1. Precision cancer medicine: the future is now, only better.

    Science.gov (United States)

    Tsimberidou, Apostolia M; Eggermont, Alexander M M; Schilsky, Richard L

    2014-01-01

    The promise of precision medicine for cancer is already being realized with the recent introduction of many targeted therapies, some with companion diagnostic tests that identify patients most likely to benefit from treatment. The utility of molecular profiling of cancer to identify actionable aberrations has been suggested by several small clinical trials conducted in patients with advanced cancer and by many anecdotes but is yet to be proven in well-designed, prospective, randomized trials. Several trials that will definitively test this strategy are now underway or soon to be launched. Melanoma, a disease once largely untreatable when metastatic, may be a paradigm for understanding how the molecular drivers of a disease can lead to highly effective targeted therapies, as well as for realizing the enormous therapeutic potential of unleashing the immune system against cancer to produce long-term disease control. Looking to the future, advanced omics technologies and computational techniques will enable assessment of not only genomic variants, as performed today, but also of pathway and network aberrations that will greatly facilitate selection of drug combinations likely to benefit specific patients. As our deepening understanding of tumor biology converges with rapid advances in measurement science and technology and computational analysis, we have an enormous opportunity to create a future for precision medicine in oncology that provides for highly specific, minimally toxic, and dramatically effective treatment for each patient.

  2. Robotic surgery in children: adopt now, await, or dismiss?

    Science.gov (United States)

    Cundy, Thomas P; Marcus, Hani J; Hughes-Hallett, Archie; Khurana, Sanjeev; Darzi, Ara

    2015-12-01

    The role of robot-assisted surgery in children remains controversial. This article aims to distil this debate into an evidence informed decision-making taxonomy; to adopt this technology (1) now, (2) later, or (3) not at all. Robot-assistance is safe, feasible and effective in selected cases as an adjunctive tool to enhance capabilities of minimally invasive surgery, as it is known today. At present, expectations of rigid multi-arm robotic systems to deliver higher quality care are over-estimated and poorly substantiated by evidence. Such systems are associated with high costs. Further comparative effectiveness evidence is needed to define the case-mix for which robot-assistance might be indicated. It seems unlikely that we should expect compelling patient benefits when it is only the mode of minimally invasive surgery that differs. Only large higher-volume institutions that share the robot amongst multiple specialty groups are likely to be able to sustain higher associated costs with today's technology. Nevertheless, there is great potential for next-generation surgical robotics to enable better ways to treat childhood surgical diseases through less invasive techniques that are not possible today. This will demand customized technology for selected patient populations or procedures. Several prototype robots exclusively designed for pediatric use are already under development. Financial affordability must be a high priority to ensure clinical accessibility.

  3. [The clinical study of familial breast cancer - now and the problems].

    Science.gov (United States)

    Nomizu, Tadashi; Matsuzaki, Masami; Katagata, Naoto; Watanabe, Fumiaki; Akama, Yoshinori

    2012-04-01

    The clinical features of familial breast cancer are characterized by early onset, high frequency of bilateral breast cancer, and multiple malignancies of other organs. It is strongly suggested that genetic factors contribute to familial breast cancer. The causative genes now identified are BRCA1 and BRCA2. This disease is called hereditary breast ovarian cancer syndrome (HBOC)because breast cancer and ovarian cancer are clustered in the kindred confirmed BRCA mutation. As for BRCA related breast cancer, early onset and highly frequent bilateral breast cancer are characteristic. In addition, the histological grade is high and the positive rate of estrogen receptors is low in BRCA1-related breast cancer. Gene diagnosis of BRCA is useful when choosing a surgical method, chemotherapy, or a surveillance of mutation carriers. The problem in Japan is that the treatment is very expensive, with poor understanding of HBOC of by clinicians and as yet immature genetic counseling system.

  4. Telescope Networks in Education: Where We Are Now and Where We Are Headed

    Science.gov (United States)

    Freed, R.

    2017-12-01

    Remote telescopes have become more common and accessible over the past 20 years as technology has evolved, and there has been a corresponding interest in bringing telescopes and astronomy into the educational arena. Numerous telescope networks (i.e. Las Cumbres Observatory, the Faulkes Telescopes, Skynet, the Harvard-Smithsonian Center for Astrophysics MicroObservatory, the SPIRIT Telescopes, iTelescope, telescope.org and others) as well as curriculum development groups and national and international programs have been developed during this time to connect students and the public with the technology and the science. While some programs and networks have come and gone, we are now at a time where sustainable communities of practice around astronomical research, ground-based telescope networks, and education can take hold and grow. The global connectivity that today's technology affords makes possible many more types of astronomical studies than in previous decades as we now have the capacity for continual sky coverage in both hemispheres by larger numbers of people and larger telescopes. Astronomy is one of few scientific fields that captures the imagination of the masses and as an undergraduate general science course it is often the last exposure to formal science that students will have and as such can play a critical role in STEM education. As the advances in computer and space exploration technologies continue, and the amount of data coming from remote observatories and space exploration missions increases astronomically, integrating remote telescope networks into educational settings, in tandem with teaching students and the general public about the nature and processes of scientific inquiry is vital not only for the field of astronomy but in helping to develop a generation of critical thinkers and informed citizens.

  5. Whites See Racism as a Zero-Sum Game That They Are Now Losing.

    Science.gov (United States)

    Norton, Michael I; Sommers, Samuel R

    2011-05-01

    Although some have heralded recent political and cultural developments as signaling the arrival of a postracial era in America, several legal and social controversies regarding "reverse racism" highlight Whites' increasing concern about anti-White bias. We show that this emerging belief reflects Whites' view of racism as a zero-sum game, such that decreases in perceived bias against Blacks over the past six decades are associated with increases in perceived bias against Whites-a relationship not observed in Blacks' perceptions. Moreover, these changes in Whites' conceptions of racism are extreme enough that Whites have now come to view anti-White bias as a bigger societal problem than anti-Black bias. © The Author(s) 2011.

  6. Apocalypse Now: elements of the Literary Journalism in thecinematographic construction by Vietnan War

    Directory of Open Access Journals (Sweden)

    Gisele Krodel Rech

    2015-06-01

    Full Text Available One of the most revered films of war, Apocalypse Now presentes fragments of journalistic representation of reality within a narrative film. They are analogies of the book Dispatches, by Michael Herr, book from the New Journalism phenomenon, which served to support the contextualization of Coppola’s masterpiece process. The intention of this paper is therefore analise the film seeking to find in these analogies textual elements of ekphrasis and fanopeia. In this process, in which the literary journalism narrative is enmeshed in film narrative, non fiction and representation of reality arises intermittently through the fictional work, in a process fraught with imagetic connotative meanings, designed from the power of text of literary journalism.

  7. Pangenesis as a source of new genetic information. The history of a now disproven theory.

    Science.gov (United States)

    Bergman, Gerald

    2006-01-01

    Evolution is based on natural selection of existing biological phenotypic traits. Natural selection can only eliminate traits. It cannot create new ones, requiring a theory to explain the origin of new genetic information. The theory of pangenesis was a major attempt to explain the source of new genetic information required to produce phenotypic variety. This theory, advocated by Darwin as the main source of genetic variety, has now been empirically disproved. It is currently a theory mainly of interest to science historians.

  8. The 39th CERN School of Computing goes to Belgium: apply now!

    CERN Multimedia

    Alberto Pace, CSC Director

    2016-01-01

    Applications are now open for CERN’s 39th School of Computing. The CSC:2016 (see here) will take place from 28 August to 10 September 2016 in Mol, Belgium, in collaboration with SCK•CEN and the Vrije Universiteit Brussel.   The two-week programme consists of more than 50 hours of lectures and hands-on exercises, all on advanced, interesting and challenging computing topics. It covers three main themes: data technologies, base technologies and physics computing. In particular, we will explore: Many-core performance optimisation Concurrent programming Key aspects of multi-threading Writing code for tomorrow’s hardware today Storage technologies, reliability and performance Cryptography, authentication, authorisation and accounting Data replication, caching, monitoring, alarms and quota Writing secure software Observing software with an attacker's eyes Software engineering for physics computing Statistical methods and pr...

  9. Post impressions "The conditions are now set... We must do it!"

    CERN Multimedia

    2002-01-01

    The Director General talks to the Bulletin   The week that Council meets at CERN can be a tense occasion, in particular when hard decisions must be made. The recent week of meetings was no exception, when the External Review Committee presented its report, and Professor Maiani presented the Management's Medium Term Plan, both in response to the increased cost-to-completion of the LHC that became apparent last year. So what was the general feeling by the end of the week? 'I really feel we have made significant progress,' Professor Maiani told the Bulletin, 'The ERC, the Council and the Management all indicate that there is only one way to go. Now we have to follow it.' The way forward, all parties agree, lies with focussing resources on the LHC. 'The LHC is technically feasible,' says Professor Maiani, 'and we know that together we can build it. It will require lots of effort and determination, but the people and structures are in place. We are in a much better position than we were 1-2 years ago. ...

  10. Cleft Palate-Craniofacial Journal 50th anniversary editorial board commentary: anatomy, basic sciences, and genetics--then and now.

    Science.gov (United States)

    Mooney, Mark P; Cooper, Gregory M; Marazita, Mary L

    2014-05-01

    To celebrate the 50th year of the Cleft Palate-Craniofacial Journal we look back to where we started in 1964 and where we are now, and we speculate about directions for the future in a "Then and Now" editorial series. This editorial examines changing trends and perspectives in anatomical, basic science, and genetic studies published in this 50-year interval. In volume 1 there were 45 total papers, seven (16%) of which were peer-reviewed basic science and genetic articles published: four in anatomy, three in craniofacial biology, and none in genetics. In contrast, in volume 50, of 113 articles there were 47 (42%) peer-reviewed basic science and genetic articles published: 30 in anatomy, five in craniofacial biology, and 12 in genetics. Topical analysis of published manuscripts then and now reveal that similar topics in anatomy and craniofacial biology are still being researched today (e.g., phenotypic variability, optimal timing of surgery, presurgical orthopedics, bone grafting); whereas, most of the more recent papers use advanced technology to address old questions. In contrast, genetic publications have clearly increased in frequency during the last 50 years, which parallels advances in the field during this time. However, all of us have noticed that the more "cutting-edge" papers in these areas are not being submitted for publication to the journal, but instead to discipline-specific journals. Concerted efforts are therefore indicated to attract and publish these cutting-edge papers in order to keep the Cleft Palate-Craniofacial Journal in the forefront of orofacial cleft and craniofacial anomaly research and to provide a valuable service to American Cleft Palate-Craniofacial Association members.

  11. University Students Seeking Hormonal Emergency Contraception: Why Do They Not Want Pregnancy Now? When is it Suitable to Have Children?

    Directory of Open Access Journals (Sweden)

    Aira Virtala

    2004-01-01

    Full Text Available University students who sought hormonal emergency contraception (EC in the Tampere Student Health Station during the period 1.9.2000-31.12.2001 received a questionnaire on their use of it. Of the total, 114 responded (67%. The aim of this study was to ascertain why the respondents did not want to get pregnant now and when it would be suitable for them to get children. Free answers to these questions were analysed using a collective consensus method. The main reasons for not wanting pregnancy now were un? nished studies and the non-steady character of the relationship. Almost all planned to become pregnant some day in the future when their life situation was appropriate, usually at the age of about 30 years.

  12. Studies in the genus Riccia (Marchantiales from southern Africa. 22. R. rubricollis, now validated, typified and described

    Directory of Open Access Journals (Sweden)

    S. M. Perold

    1991-09-01

    Full Text Available Riccia rubricollis is a very rare endemic species, only known from a few collections by Duthie at Knysna. Unfortunately she and Garside did not publish anything on it, and Arnell's (1963 description has neither a Latin diagnosis nor was a type specimen cited. These omissions have now been rectified here, following the recent rediscovery of Duthie's collections at BOL.

  13. Mainstream web standards now support science data too

    Science.gov (United States)

    Richard, S. M.; Cox, S. J. D.; Janowicz, K.; Fox, P. A.

    2017-12-01

    The science community has developed many models and ontologies for representation of scientific data and knowledge. In some cases these have been built as part of coordinated frameworks. For example, the biomedical communities OBO Foundry federates applications covering various aspects of life sciences, which are united through reference to a common foundational ontology (BFO). The SWEET ontology, originally developed at NASA and now governed through ESIP, is a single large unified ontology for earth and environmental sciences. On a smaller scale, GeoSciML provides a UML and corresponding XML representation of geological mapping and observation data. Some of the key concepts related to scientific data and observations have recently been incorporated into domain-neutral mainstream ontologies developed by the World Wide Web consortium through their Spatial Data on the Web working group (SDWWG). OWL-Time has been enhanced to support temporal reference systems needed for science, and has been deployed in a linked data representation of the International Chronostratigraphic Chart. The Semantic Sensor Network ontology has been extended to cover samples and sampling, including relationships between samples. Gridded data and time-series is supported by applications of the statistical data-cube ontology (QB) for earth observations (the EO-QB profile) and spatio-temporal data (QB4ST). These standard ontologies and encodings can be used directly for science data, or can provide a bridge to specialized domain ontologies. There are a number of advantages in alignment with the W3C standards. The W3C vocabularies use discipline-neutral language and thus support cross-disciplinary applications directly without complex mappings. The W3C vocabularies are already aligned with the core ontologies that are the building blocks of the semantic web. The W3C vocabularies are each tightly scoped thus encouraging good practices in the combination of complementary small ontologies. The W3C

  14. Addressing Early Warning Indicators: Interim Impact Findings from the Investing in Innovation (i3) Evaluation of Diplomas Now

    Science.gov (United States)

    Corrin, William; Sepanik, Susan; Rosen, Rachel; Shane, Andrea

    2016-01-01

    Diplomas Now is a partnership of three national organizations--Talent Development Secondary, City Year, and Communities In Schools--collaborating in an effort to transform urban secondary schools so that fewer students drop out and more graduate ready for postsecondary education and work. With the goal of a continuous system of support through…

  15. Prevention of diabetes with pioglitazone in ACT NOW: physiologic correlates.

    Science.gov (United States)

    Defronzo, Ralph A; Tripathy, Devjit; Schwenke, Dawn C; Banerji, Maryann; Bray, George A; Buchanan, Thomas A; Clement, Stephen C; Gastaldelli, Amalia; Henry, Robert R; Kitabchi, Abbas E; Mudaliar, Sunder; Ratner, Robert E; Stentz, Frankie B; Musi, Nicolas; Reaven, Peter D

    2013-11-01

    We examined the metabolic characteristics that attend the development of type 2 diabetes (T2DM) in 441 impaired glucose tolerance (IGT) subjects who participated in the ACT NOW Study and had complete end-of-study metabolic measurements. Subjects were randomized to receive pioglitazone (PGZ; 45 mg/day) or placebo and were observed for a median of 2.4 years. Indices of insulin sensitivity (Matsuda index [MI]), insulin secretion (IS)/insulin resistance (IR; ΔI0-120/ΔG0-120, ΔIS rate [ISR]0-120/ΔG0-120), and β-cell function (ΔI/ΔG × MI and ΔISR/ΔG × MI) were calculated from plasma glucose, insulin, and C-peptide concentrations during oral glucose tolerance tests at baseline and study end. Diabetes developed in 45 placebo-treated vs. 15 PGZ-treated subjects (odds ratio [OR] 0.28 [95% CI 0.15-0.49]; P IGT > T2DM) was associated with improvements in insulin sensitivity (OR 0.61 [95% CI 0.54-0.80]), IS (OR 0.61 [95% CI 0.50-0.75]), and β-cell function (ln IS/IR index and ln ISR/IR index) (OR 0.26 [95% CI 0.19-0.37]; all P < 0.0001). Of the factors measured, improved β-cell function was most closely associated with final glucose tolerance status.

  16. Double-beta decay: Physics beyond the standard model now and in the future (GENIUS)

    International Nuclear Information System (INIS)

    Klapdor-Kleingrothaus, H.V.

    1998-01-01

    Nuclear double beta decay has an extraordinarily broad potential in searches for physics beyond the Standard Model, probing already now the TeV scale, at which new physics is expected to manifest itself. These possibilities are reviewed here. First, the result of present-generation experiments are discussed. The most sensitive one of these, the Heidelberg-Moscow experiment at the Gran Sasso underground laboratory, probes the electron mass now in the sub-eV region and will reach a limit of some 0.1 eV in a few years. On the basis of a large amount of theoretical work done by the Heidelberg Double Beta Group in the last two years, results are obtained also for SUSY models (R-parity breaking and neutrino mass), for leptoquarks (leptoquark-Higgs boson coupling), for compositeness, for right-handed W-boson mass, and for some other problems. These results are comfortably competitive with corresponding results from high-energy accelerators like Tevatron, HERA, etc. Future prospects for ββ research are discussed. A new Heidelberg experimental proposal (GENIUS) is presented, which would make it possible to increase the sensitivity for the Majorana neutrino masses from the present level of at best 0.1 eV down to 0.01 or even 0.001 eV. Its physical potential would be a breakthrough into the multi-TeV range for many models beyond standard. Its sensitivity for neutrino-oscillation parameters would be higher than that of all present terrestrial neutrino-oscillation experiments and that of those planned for the future. It would further, even at a first step, cover almost the full MSSM parameter space for prediction of neutralinos as cold dark matter, making the experimental competitive with LHC in searches for supersymmetry

  17. Building a Sustainable Energy Future for Africa - Acting Now and Together

    Energy Technology Data Exchange (ETDEWEB)

    Fall, L.

    2007-07-01

    The key energy challenges Africa is facing are: low level of access to commercial energy, low per capita energy consumption, weak development of energy infrastructure and lack of investment and financing for energy projects. Addressing these challenges is critical for sustainable economic and social development, and assured access to secure, affordable and reliable energy. In spite of these daunting challenges, Africa is well endowed in energy resources, but these resources are largely untapped and concentrated in a few countries. In addition, there are numerous 'rooms' for opportunities that could be seized concretely to overcome the main obstacles to the Sustainable Energy Development of the Continent. Thus, right actions must be taken to overcome these obstacles, including: financing the huge needed investments, technological development, private-public partnerships, energy market reform and effective regulation, sound and sustainable energy policies, and economic and social measures. Subsequently, from priority areas, the related stakeholders should 'act now' and 'act together', through effective collaboration and partnership and making proper alliances, to initiate effective and concrete actions to support Africa aspirations in order to build a Sustainable Energy Future for Africa, in a cost-effective and timely manner. (auth)

  18. Enhancing research quality and reporting: why the Journal of Comorbidity is now publishing study protocols

    Directory of Open Access Journals (Sweden)

    Susan Smith

    2014-08-01

    Full Text Available The Journal of Comorbidity was launched in 2011 and has since become established as a high-quality journal that publishes open-access, peer-reviewed articles, with a focus on advancing the clinical management of patients with comorbidity/multimorbidity. To further enhance research quality and reporting of studies in this field, the journal is now offering authors the opportunity to publish a summary of their study protocols – a move designed to generate interest and raise awareness in ongoing clinical research and to enable researchers to detail their methodologies in order that replication by scientific peers is possible.

  19. Will you be alive 10 years from now? and numerous other curious questions in probability

    CERN Document Server

    Nahin, Paul J

    2013-01-01

    What are the chances of a game-show contestant finding a chicken in a box? Is the Hanukkah dreidel a fair game? Will you be alive ten years from now? These are just some of the one-of-a-kind probability puzzles that acclaimed popular math writer Paul Nahin offers in this lively and informative book. Nahin brings probability to life with colorful and amusing historical anecdotes as well as an electrifying approach to solving puzzles that illustrates many of the techniques that mathematicians and scientists use to grapple with probability. He looks at classic puzzles from the past--from Galil

  20. Improved organic scintillation detectors; Possibilites de perfectionnement des detecteurs organiques a scintillations; Usovershenstvovannye organicheskie stsintillyatsionnye detektory; Detectores organicos de centelleo perfeccionados

    Energy Technology Data Exchange (ETDEWEB)

    Birks, J B [University of Manchester, Manchester (United Kingdom)

    1962-04-15

    Equations have been derived for the practical scintillation efficiency (photo-electrons/MeV) of organic crystals and solutions in terms of molecular parameters and these have been applied to the more important scintillator systems, for photomultipliers with S11 (glass window) and S13 (quartz window) responses. The results suggest several improvements in current organic scintillation detector practice: the use of binary rather than ternary solutions; the use of quartz rather than glass windows; and the reconsideration of mixed crystal scintillators based on naphthalene. Improvements by factors of 2 or more in the figure of merit (practical efficiency/decay time) for fast-scintillation counting can be obtained. (author) [French] L'auteur a etabli des equations pour determiner le rendement de scintillation (photoelectrons/MeV) de cristaux et solutions organiques, en faisant intervenir des parametres moleculaires. Il a applique ces equations a des appareils a scintillations plus importantes pour determiner la reponse des photomultiplicateurs a fenetre en verre (S11) et a fenetre en quartz (S13). Les resultats obtenus ont fait apparaitre la possibilite d'ameliorer, a plusieurs egards, les detecteurs organiques a scintillations du type courant, par exemple en remplacant les solutions ternaires par des solutions binaires, les fenetres en verre par des fenetres en quartz, ou en reexaminant les possibilites offertes par les scintillateurs a cristaux mixtes a base de naphtalene. L'introduction de ces perfectionnements conduirait a une amelioration, du simple au double ou plus, du facteur de qualite (efficacite/temps de decroissance) des dispositifs de comptage a scintillations. (author) [Spanish] Se han establecido ecuaciones que permiten calcular el rendimiento practico de centelleo (fotoelectrones/MeV) de los cristales y soluciones organicos en funcion de parametros moleculares; estas ecuaciones han sido aplicadas a los sistemas de centelleo mas importantes, para fotomultiplicadores con respuestas S11 (ventana de vidrio) y S13 (ventana de cuarzo). Los resultados sugieren la posibilidad de perfeccionar de varias maneras los actuales metodos de utilizacion de detectores organicos: empleo de soluciones binarias con preferencia a las ternarias; empleo de ventanas de cuarzo con preferencia a las de vidrio; nueva evaluacion de los detectores de cristales mixtos basados en el naftaleno. El indice de calidad (rendimiento practico/periodo de caida de la luminiscencia) puede llegar a aumentar al doble para el contaje rapido con detectores de centelleo. (author) [Russian] Byli vyvedeny uravneniya dlya opredeleniya dejstvitel'noj ehffektivnosti stsintillyatsii-(chislo foto- ehlektronov na 1 mehv) organicheskikh kristallov i rastvorov s tochki zreniya molekulyarnykh parametrov; ehti uravneniya byli primeneny k bolee slozhnym sistemam stsintillyatorov dlya fotoumnozhitelej s kharakteristikami S11 (steklyannoe okno) i S13 (kvartsevoe okno). Rezul'taty ukazyvayut na vozmozhnost' vneseniya ryada usovershenstvovanij v sushchestvuyushchuyu konstruktsiyu organicheskikh stsintillyatsionnykh detektorov, a imenno: ispol'zovanie binarnykh rastvorov vmesto trojnykh; ispol'zovanie kvartsevogo okna vmesto steklyannogo; peresmotr stsintillyatorov so smeshannymi kristallami na osnove naftalina. Takim obrazom mozhno uvelichit' vdvoe ili dazhe eshche bol'she chuvstvitel'nost' (dejstvitel'naya ehffektivnost', otnesennaya ko vremeni raspada) bystro stsintillyatsionnogo scheta. (author)

  1. Examining the Average Citation Index of "Education in Rural Australia" (Now the "Australian and International Journal of Rural Education")

    Science.gov (United States)

    Drummond, Aaron; Halsey, R. John

    2013-01-01

    The journal "Education in Rural Australia" (now the "Australian and International Journal of Rural Education") has been in existence since 1991. During the Excellence in Research Australia (ERA) period, the journal maintained a B ranking, indicating that it was a quality journal within a specialised field. With the abolishment…

  2. 77 FR 30349 - Alderox, Inc., Applied Solar, Inc., Artes Medical, Inc., AskMeNow, Inc., Blink Logic Inc., and...

    Science.gov (United States)

    2012-05-22

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] Alderox, Inc., Applied Solar, Inc., Artes Medical, Inc., AskMeNow, Inc., Blink Logic Inc., and Convergence Ethanol, Inc.; Order of Suspension of... Blink Logic Inc. because it has not filed any periodic reports since the period ended June 30, 2009. It...

  3. Facebook, Twitter, Instagram, Pinterest – nowe perspektywy badawcze

    Directory of Open Access Journals (Sweden)

    Maria Czarkowska

    2017-12-01

    Full Text Available Facebook, Twitter, Instagram, Pinterest – new research perspectivesThe goal of this paper is to present the vast array of content that is emerging within social media platforms: Facebook, Twitter, Instagram and Pinterest and analyze the ways in which they can be classified. This is a review of the available interdisciplinary methods and factors that should be taken into consideration when researching the genelogy of the texts that arise in the network. The Internet has changed the face of social communication. It has highlighted processes that were much less visible before. The challenge for researchers is to analyze the enormous amount of content and incorporate it into a classification system. Above all, statements made on social media platforms, such as Facebook, Twitter, Instagram and Pinterest, require analysis. Previous attempts to systematize them did not correspond to the reality of the network. Research on the Internet genres and communication forms requires the use of relevant analytical tools and interdisciplinary approaches.   Facebook, Twitter, Instagram, Pinterest – nowe perspektywy badawczeCelem publikacji jest zaprezentowanie ogromnej liczby różnorodnych treści, które powstają w ramach platform społecznościowych: Facebook, Twitter, Instagram i Pinterest, oraz analiza dostępnych sposobów ich klasyfikacji. Chodzi zatem o przegląd dostępnych interdyscyplinarnych metod i czynników, które warto brać pod uwagę przy badaniach genologicznych tekstów, które powstają w sieci. Internet zmienił oblicze społecznej komunikacji. Uwypuklił procesy, które do tej pory nie były tak widoczne. Wyzwaniem dla badaczy jest analiza ogromnej ilości treści i ujęcie ich w system klasyfikacji. Analizy wymagają przede wszystkim komunikaty powstające w ramach mediów społecznościowych, takich jak Facebook, Twitter, Instagram i Pinterest. Dotychczasowe próby systematyzacji nie odpowiadały realiom sieci. Badania form

  4. Twenty years of multidisciplinary research and practice: the Journal of Occupational Rehabilitation then and now.

    Science.gov (United States)

    Shaw, William S; Findley, Patricia A; Feuerstein, Michael

    2011-12-01

    Early research of work disability in the 1980s showed a complexity of factors influencing pain and health-related functional limitation at work; hence, multidisciplinary perspectives were necessary to understand the complex interplay between biomechanical, organizational, social, and psychological factors impacting work disability. To address this need, the Journal of Occupational Rehabilitation was founded in 1991 with the goal of providing a scientific, yet practical forum for presenting multidisciplinary research and practice in work disability. Now, the 20-year collection of articles in the Journal reflects important trends and directions in the field of occupational rehabilitation. We conducted a retrospective summary of the past 20 years of the Journal of Occupational Rehabilitation, including its inaugural goals and intent, rates of submission and acceptance, trends in the types of articles published, study topics, global distribution of authors, and future directions. The original goal of providing a multidisciplinary scientific and practical forum has been met, but current trends reflect a maturing scientific evidence base, with less representation of employer-based case studies and practical innovations. There has been a dramatic increase in the international representation of studies, authors, and peer reviewers outside of the US. Also, published studies now address work disability for a larger number of health concerns. Contributions to the Journal continue to reflect a multidisciplinary perspective, but the Journal has seen significant changes with respect to international representation, the expanding study of non-musculoskeletal sources of work disability, and the maturing scientific evidence base in the field of occupational rehabilitation. Future volumes of the Journal will likely reflect continuing changes in the global economy, workforce fitness, and job demands.

  5. Solar energy is for now. [Question/answer session with Dr. Barry Commoner

    Energy Technology Data Exchange (ETDEWEB)

    Commoner, B

    1977-01-01

    Dr. Commoner, in a question/answer format, presents his views on the energy crisis, the part played by OPEC, the part played by the wastage of energy to the problem. He discusses the vulnerability of our economy to the destruction of energy supplies. In discussing alternative energy sources, Commoner says that ''there are only two possible sources of renewable energy. One is solar. . .and the other is nuclear with the breeder.'' But he does feel that the choice for nuclear ''would be a disastrous mistake, partly for obvious environmental reasons and questions of nuclear proliferation but, even more important, for economic considerations. . .'' Solar energy is economical and all the technology exists, he adds. ''Right now, throughout the central band of the USA, it is economic to replace 50 to 60 percent of your conventional heating by building solar collectors,'' he continues. He further discusses other alternative energy sources in the interview and concludes with his views on how seriously energy problems in the U.S. affect the rest of the world. (MCW)

  6. How and Why To Free All Refereed Research From Access- and Impact-Barriers Online, Now

    CERN Document Server

    Harnad, S; Brody, T

    2001-01-01

    Researchers publish their findings in order to make an impact on research, not in order to sell their words. Access-tolls are barriers to research impact. Authors can now free their refereed research papers from all access tolls immediately by self-archiving them on-line in their own institution's Eprint Archives. Free eprints.org software creates Archives compliant with the Open Archives Initiative metadata-tagging Protocol OAI 1.0. These distributed institutional Archives are interoperable and can hence be harvested into global "virtual" archives, citation-linked and freely navigable by all. Self-archiving should enhance research productivity and impact as well as providing powerful new ways of monitoring and measuring it.

  7. Adult vaccination: Now is the time to realize an unfulfilled potential

    Science.gov (United States)

    Tan, Litjen

    2015-01-01

    Each year, vaccine-preventable diseases kill thousands of adults, both in the United States and across the planet, causing a significant human toll and severe economic burden on the world's healthcare systems. In the United States, while immunization is recognized as one of the most effective primary prevention services that improves health and well-being, adult immunization rates remain low and large gaps exist between national adult immunization goals and actual adult immunization rates. Closing these gaps requires a commitment by national leaders to a multifaceted national strategy to: (1) establish the value of adult vaccines in the eyes of the public, payers, policy makers, and health care professionals; (2) improve access to recommended adult vaccinations by improving the adult vaccine infrastructure in the United States and developing public-private partnerships to facilitate effective immunization behaviors; and (3) ensure fair and appropriate payment for adult immunization. Many of the situations that result in low adult immunizations rates in the United States also exist in many other countries around the world. Successful strategies to improve adult immunization coverage rates will result in reductions in morbidity, mortality, and healthcare costs. All medical and public health stakeholders must now collaborate to realize the significant health benefits that come with a strong adult immunization program. PMID:26091249

  8. Beeswax in Asante Castings: The Then, Now and the Way Forward

    Directory of Open Access Journals (Sweden)

    Samuel Baah Kissi

    2016-10-01

    Full Text Available Beeswax used for Asante casting by Krofofrom artisans and the Asantehene gild of metalsmiths in the 1700`s are extracted naturally without further chemical treatment to enhance their workability. Although modelling with this wax is very effective, mass production technique now adopted by local artisans and the inflow of machine made artefacts due to globalization has crippled the sale of locally manufactured artefacts. This research dives into various ways of manipulating the natural beeswax using conventional waxes to help achieve complex and competitive designs suitable for the international feed. Qualitative research design approach was used and the descriptive and experimental research methodologies were employed. A comparative analysis was conducted on the production processes employed in the 1700`s and those practiced by various cultures in Africa and experiment was conducted on beeswax to ascertain a suitable wax formulation for the production of complex shapes and sizes using simple Jewellery technique less employed by local metal artisans for casting. It was found that the addition of various additives to the beeswax improved its workability and also the use of Plaster of Paris in wax modelling should be adapted as used in this research for traditional mass production for maximum yield and less stress.

  9. Women service members, veterans, and their families: What we know now.

    Science.gov (United States)

    Mankowski, Mariann; Everett, Joyce E

    2016-12-01

    The purpose of this paper is to highlight what we know now about female service members, veterans, and their families. The experiences of U.S. female service members and veterans are more complex than previous eras and significant demographic changes have taken place. U.S. female veterans are more likely to be younger, come from ethnic and racial minority groups, have children, and combat exposure. U.S. female service members report high rates of sexual violence and they are more vulnerable to homelessness and unemployment when compared to previous female military cohorts. U.S. female service members and veterans are also at higher risk for significant mental and health issues. Children and adolescents of women service members and veterans may also carry a heavy burden as a result of lengthy deployments. A majority of female service members and veterans will utilize community based healthcare and social services, therefore, it is essential that all healthcare providers understand the unique needs of this cohort of women. Practice implications at the micro, mezzo, and macro levels are discussed. Qualitative and quantitative studies that expand our understanding of women's experience in the military and as veterans are encouraged. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Bedside diagnosis of imported malaria using the Binax Now malaria antigen detection test

    DEFF Research Database (Denmark)

    Wiese, Lothar; Bruun, Brita; Baek, Leif

    2006-01-01

    Malaria may be misdiagnosed in non-endemic countries when the necessary experience for rapid expert microscopy is lacking. Rapid diagnostic tests may improve the diagnosis and may play a role as a bedside diagnostic tool. In a multicentre study we recruited patients suspected of malaria over...... a period of 14 months. The Binax Now Malaria rapid test was used at the bedside and in the clinical microbiology laboratory. The training of clinical staff was monitored and their experience with the use of the test was recorded. 542 patients were included, 80 of whom had malaria diagnosed by microscopy...... be useful for the diagnosis of P. falciparum malaria when used by routine laboratory staff, but could lead to misdiagnoses when used at the bedside. Microscopy is still essential in order to identify the few missed diagnoses, to determine the degree of parasitaemia, and to ensure species diagnosis...

  11. Noninvasive prenatal testing: the future is now.

    Science.gov (United States)

    Norwitz, Errol R; Levy, Brynn

    2013-01-01

    available from nucleated blood cells extracted from a similar volume of whole maternal blood. There have now been numerous reports on the use of cell-free DNA (cfDNA) for NIPT for chromosomal aneuploidies-especially trisomy (an extra copy of a chromosome) or monosomy (a missing chromosome)-and a number of commercial products are already being marketed for this indication. This article reviews the various techniques being used to analyze cell-free DNA in the maternal circulation for the prenatal detection of chromosome abnormalities and the evidence in support of each. A number of areas of ongoing controversy are addressed, including the timing of maternal blood sampling, the need for genetic counseling, and the use of confirmatory invasive testing. Future applications for this technology are also reviewed.

  12. Now You See Me Now You Don’t:

    DEFF Research Database (Denmark)

    Ventura, Joanthan; Gunn, Wendy

    embarrassment or stigma. In other cases, designing paramedical objects along the lines of extreme sports or high-fashion designers accentuate the end user's body, hence enabling people to reacquire their dignity. We ask then can a more socially aware design approach focusing upon generational, relational......The body as an anthropological nexus of socio-cultural norms and conventions has been discussed at length in the humanities and social sciences. However, within the worlds of industrial design, an important player influencing an understanding of the users body within a design process has been...... neglected and that is the industrial designer. Our main thesis concerning understandings of the user's body is, that designing is an anthropological, socio-cultural and physical praxis, in the midst of which stand people(s) engaging within their material environments. We propose, by involving participatory...

  13. Foetal dosimetry--is the ICRP dosimetric system for humans now complete?

    Energy Technology Data Exchange (ETDEWEB)

    Jones, Steve [Westlakes Research Institute, Cumbria (United Kingdom)

    2002-03-01

    Internal dosimetry is possibly the most complex area of science associated with radiological protection, and has a long history. Primary control of internal exposure now relied on control of annual intakes rather than limitation of organ burdens. Although it took nearly a decade for regulations and hence the practice of occupational radiation protection to fully adopt the new recommendations, the new dosimetric concepts were quite rapidly adopted in the assessment of public exposure because the new methods provided a more natural means of assessing the significance of exposure to a combination of external and internal exposure involving a number of different radionuclides. As a result, following the ICRP's initial publication of dosimetric models for occupational exposure, adaptations became available to cover environmental exposure, including the exposure of infants and children. Increasingly sophisticated biokinetic and dosimetric models have now been developed which, together with the welcome availability of dose per unit intake factors in CD-ROM form make it easy for the radiation protection practitioner to assess committed effective doses, and committed equivalent doses to individual organs, to occupationally exposed adults and environmentally exposed infants, children and adults. The inability to readily assess doses to the developing foetus has, however, long been perceived as a significant gap in knowledge with implications for the study of childhood leukaemia in the vicinity of nuclear installations and possibly also the control of occupational exposure for women of child-bearing age. The first systematic assessment of doses to the foetus was in connection with the study of childhood leukaemia in the vicinity of Sellafield in the UK, for which preliminary models were developed. Since that time a few publications giving guidance on the calculation of foetal doses have emerged and more sophisticated assessments of foetal dose have been reported

  14. Why MDMA therapy for alcohol use disorder? And why now?

    Science.gov (United States)

    Sessa, Ben

    2017-11-07

    Alcohol use disorder represents a serious clinical, social and personal burden on its sufferers and a significant financial strain on society. Current treatments, both psychological and pharmacological are poor, with high rates of relapse after medical detoxification and dedicated treatment programs. The earliest historical roots of psychedelic drug-assisted psychotherapy in the 1950s were associated with Lysergic acid diethylamide (LSD)-assisted psychotherapy to treat what was then called, alcoholism. But results were varied and psychedelic therapy with LSD and other 'classical' psychedelics fell out of favour in the wake of socio-political pressures and cultural changes. A current revisiting of psychedelic clinical research is now targeting substance use disorders - and particularly alcohol use disorder - again. 3,4-Methylenedioxymethamphetamine (MDMA)-assisted psychotherapy has never been formally explored as a treatment for any form of substance use disorder. But in recent years MDMA has risen in prominence as an agent to treat posttraumatic stress disorder (PTSD). With its unique receptor profile and a relatively well-tolerated subjective experience of drug effects when used clinically, MDMA Therapy is ideally suited to allow a patient to explore and address painful memories without being overwhelmed by negative affect. Given that alcohol use disorder is so often associated with early traumatic experiences, the author is proposing in a current on-going UK-based study that patients with alcohol use disorder who have undergone a medical detoxification from alcohol might benefit from a course of MDMA-assisted psychotherapy. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. From Wagons to Race Cars, At Least Now We Have A Chassis

    Science.gov (United States)

    Morrow, A. L.

    2003-12-01

    For the past 30 years Very-Long-Baseline Interferometry (VLBI) has provided astronomers with the most accurate measurements to date of both distant radio sources as well as the tectonic plates. The resolutions attainable through VLBI are orders of magnitude better than other instruments. In order to transmit radio signals collected at different sites to a correlator for processing the VLBI data was stored on magnetic tapes, and then the magnetic tapes were shipped through the mail to the central processing site. This was not only arduous and inefficient, it was also costly. Now this means of shipment can be replaced by global high speed networks. This means of transmission is called e-VLBI. New protocols must be developed so e-VLBI can become a proficient high bandwidth background user. The protocol agreed upon uses a Real-time Transport Protocol (RTP) framework to preserve timing information and synchronization. The RTP is then transported using the Internet User Datagram Protocol (UDP) with RTP Control Protocol (RTCP) monitoring the networks performance. When this protocol is fully functional astronomers will be able to observe all over the world and receive results in real time.

  16. Now that California has AMI, what can the state do with it?

    International Nuclear Information System (INIS)

    Woo, C.K.; Kollman, E.; Orans, R.; Price, S.; Horii, B.

    2008-01-01

    Recognizing the lack of retail-demand response, a state regulator, such as the California Public Utilities Commission (CPUC), seeks tariff proposals that transmit wholesale price signals to a local distribution company's (LDC) retail customers. To enable these proposals, the CPUC has authorized funding for advanced metering infrastructure (AMI) for two investor-owned LDCs. Assuming regulatory approval of the third LDC's application, the state's US$4.28 billion AMI investment will aid new rate designs for 11.3 million electricity customers. Now that California has AMI, what can the state do with it? With AMI in hand, an LDC can implement service options that can further the state's energy initiatives, ranging from resource adequacy requirement (RAR) to greenhouse gas (GHG) emissions reduction. These options can efficiently allocate limited capacity based on each customer's willingness to pay, without the unnecessary distinction between price rationing and reliability differentiation. They can be Pareto superior, welfare dominating the default tariffs that apply to these customers. A case in point is the generalized demand subscription service (GDSS) option proposed in this paper. However, it is unclear whether the option will find wide customer acceptance, without an LDC's intensive customer education and marketing efforts

  17. What nanomedicine in the clinic right now really forms nanoparticles?

    Science.gov (United States)

    Svenson, Sonke

    2014-01-01

    Some researchers believe nanomedicine will revolutionize healthcare and medicine through transformative new therapeutic tools. Nanocarriers, utilized to transport actives to the target site, are constructed from a wide range of materials. Nanocarriers can be grouped into self-assembling (liposomes, micelles), processed (nanoparticles, emulsions), and chemically bound (dendrimers, silica-based carriers, carbon nanotubes) structures. A review of nanomedicines on the market and in clinical translation reveals that the vast majority is based on liposomes, polymeric micelles, and nanoparticles. The increasing presence of these novel nanomedicines raises the question what nanomedicines in the clinic right now really form nanoparticles, i.e., are improvements we see from nanomedicines structure-related or do they result from improved formulations? Do we even have sufficient data to address this question? The formation of nanocarriers is usually confirmed in vitro but little if any in vivo (let alone clinical) information is available. Given the large number of nanomedicines on the market and under clinical evaluation one clearly cannot expect to find a 'one size fits all' answer. Therefore, two case studies are discussed: the paclitaxel formulation Taxol® and its nanomedicine companions LEP-ETU (liposome), Genexol®-PM and NK105 (micelles), and Abraxane® (nanoparticle). Published pharmacokinetic data is utilized to find differences indicating nanocarrier delivery. The second case study involves structurally related camptothecin-polymer conjugates CRLX101 (nanoparticles) and XMT-1001 (prodrug). Structural differences are evaluated to discuss the different aggregation behavior. This opinion can only serve as first attempt to find a more general answer; clearly more data is needed from future studies. © 2014 Wiley Periodicals, Inc.

  18. Clean Cities Now, Vol. 20, No. 2, Winter 2017 - Capitalizing on Core Strengths & New Technologies for Today's Mobility Systems

    Energy Technology Data Exchange (ETDEWEB)

    2017-01-01

    Clean Cities Now is the official semi-annual newsletter of Clean Cities, an initiative designed to reduce petroleum consumption in the transportation sector by advancing the use of alternative and renewable fuels, fuel economy improvements, idle-reduction measures, and new technologies, as they emerge.

  19. And now, Jose? The punctuation by the bias of the notions of lack and excess

    Directory of Open Access Journals (Sweden)

    Marilei Resmini Grantham

    2017-11-01

    Full Text Available This work has as its starting point the concepts developed and operationalized by Ernst (2009 in the text “Lack, excess and strangeness in the constitution / interpretation of the discursive corpus”. Of the three notions developed by Ernst in her work, I pay attention to those of lack and excess, and I propose to examine these concepts through the bias of punctuation. With this purpose, I choose as an analytical corpus the poem “José”, by Carlos Drummond de Andrade, and, particularly, the formulation “And now, José?”, present throughout the poem. My goal is to work on the notions developed by Ernst, evidencing the discursive functioning of punctuation and seeking to expand my own reflections.

  20. Hollywood Now.

    Science.gov (United States)

    Fadiman, William

    A behind-the-scenes look at Hollywood's film industry reveals the roles and functions of its agents, directors, stars, writers, producers, and technicians. Economy is the dominant motivational factor affecting everyone connected with Hollywood; actors, scripts, and film production specialists are evaluated entirely in dollars. Coping with this…

  1. Now What?

    Science.gov (United States)

    Stuart, Reginald

    2012-01-01

    When officials at tuition-driven Fisk University raised the veil of secrecy a few years ago surrounding the university's financial condition, the details they laid out were less than encouraging. The Nashville-based university, home of the historic Jubilee Singers, was losing several million dollars a year and had not received any major private…

  2. Apothecary.now.

    Science.gov (United States)

    Menduno, M

    1999-07-01

    The race is on to e-volutionize the nation's $100 billion prescription drug business à la Amazon.com. There's just one cyber-size glitch: Most doctors aren't set up for e-commerce, which means calling, faxing, or snail-mailing scripts to Internet pharmacies. E-volution? Maybe. Revolution? Hardly.

  3. Whither now?

    Directory of Open Access Journals (Sweden)

    C.A.E. GOODHART

    1997-12-01

    Full Text Available The author is one of the UK's eminent monetary economists and a member of the UK's Monetary Policy Committee. After summarising his early academic career, he discusses his time at the Bank of England and the formation of UK monetary policy. This leads on to a survey of his later experiences in returning to academia and his analysis of foreign exchange markets and central bank autonomy. The movements of foreign exchange markets have been thought to react upon the arrival of news concerning changes in monetary policy. However, close examination of the US forex market does not show any significant fluctuations in reaction to particular news disclosures. Economic news with pre-announced release dates have been proven to produce jumps in volatility within minutes of disclosure. The use of high frequency data at given intervals has been shown to produce price spikes and subsidence after a few minutes.

  4. Photodetachment now

    International Nuclear Information System (INIS)

    Fink, J.H.

    1987-10-01

    To illustrate the feasibility of photodetachment, the author describes a conceptual design of photo-neutralizers for 0.5 and 3.0 MeV deuterium beams. The negative ions are stripped in optical cavities using large mirrors with higher than 99.99% reflectivity. The neutralizers are illuminated by an array of Nd:YAG slab-lasers emitting about 30 kW/m of light per unit length, while the mirrors are exposed to an irradiance of the order of 100 MW/m 2 . Details of the photodetachment cells and the laser configurations have not been resolved. 9 refs., 6 figs

  5. Vylepšení nástroje ServiceNow Discovery v oblastech aplikačních vztahů a konfigurací aplikací

    OpenAIRE

    Toman, František

    2014-01-01

    The main focus of this paper is to improve the ServiceNow Discovery tool in two areas. The first one is the Application Dependency Mapping (ADM). ServiceNow is currently not able to determine the type of the relationship between two applications. As a solution, a new application was designed and implemented. It enables human element to define the type of relationship before it is found by the Discovery. This application also makes it posiible to define rules, which affect the behaviour of ADM...

  6. Analýza implementácie vybraných modulov nástroja ServiceNow s ich predlohou vo forme súboru najlepšej praxe knižnice ITIL

    OpenAIRE

    Vacula, Filip

    2016-01-01

    This thesis is dedicated to the ServiceNow ITSM tool, and its comparison to ITIL. The main goal is to analyze the differences and similarities between implementation of Incident, Problem and Change Management processes in ServiceNow, and their model presented by the best practice recommendations of the ITIL library.

  7. Crisis or not, renewable energy is hot. To reap the rewards, governments and companies should act now

    International Nuclear Information System (INIS)

    2009-03-01

    2009 brings us new and difficult challenges. But it also offers real opportunities to change the course of our economies and the impact of the environmental footprint we will leave behind. As the European Union's 2020 environmental targets - 20% less CO2, 20% more energy efficiency, and an overall energy mix comprising 20% renewables - loom nearer, data suggests we are not yet on course to meet these ambitious targets. Despite the economic downturn, now is the time for action. The investments required in renewables could contribute to reverse the economic downtrend. To provide a sound basis for that action, PwC recently examined Europe's future renewable energy marketplace through the lens of progress towards the 2020 goals. This PwC study considers the market's potential, compares approaches in various countries, and puts forth some high-level recommendations for how governments and companies can reap the rewards. Making renewable energy 20% of total energy consumption in the 27 countries of the EU will require an investment of 1.8 to 7.3 trillion euros over the next decade depending on the type of renewable technology. In practical terms, that will mean building more than a million windmills or installing enough solar panels to cover an area twice the size of Belgium. A formidable challenge, no doubt. The opportunities, however, are proportionate to that challenge. The take-away from this study is really quite simple: The renewable market is set to become a major part of the energy sector - and the time to act is now

  8. The "here and now" of youth: the meanings of smoking for sexual and gender minority youth.

    Science.gov (United States)

    Antin, Tamar M J; Hunt, Geoffrey; Sanders, Emile

    2018-05-31

    The mainstream tobacco field in the USA tends to situate youth as passive, particularly in terms of their susceptibility to industry manipulation and peer pressure. However, failing to acknowledge youths' agency overlooks important meanings youth ascribe to their tobacco use and how those meanings are shaped by the circumstances and structures of their everyday lives. This article is based on analysis of 58 in-depth qualitative interviews conducted with sexual and gender minority youth living in the San Francisco Bay area in California. Topics covered in interviews focused on meanings of tobacco in the lives of youth. Interviews lasted approximately 2.5 h and were transcribed verbatim and linked with ATLAS.ti, a qualitative data analysis software. Following qualitative coding, narrative segments were sorted into piles of similarity identified according to principles of pattern-level analysis to interpret to what extent meanings of smoking for young people may operate as forms of resistance, survival, and defense. Analysis of our participants' narratives highlights how smoking is connected to what Bucholtz calls the "'here-and-now' of young people's experience, the social and cultural practices through which they shape their worlds" as active agents (Bucholtz, Annu Rev Anthropol31:525-52, 2003.). Specifically, narratives illustrate how smoking signifies "control" in a multitude of ways, including taking control over an oppressor, controlling the effects of exposure to traumatic or day-to-day stress, and exerting control over the physical body in terms of protecting oneself from violence or defending one's mental health. These findings call into question the universal appropriateness of foundational elements that underlie tobacco control and prevention efforts directed at youth in the USA, specifically the focus on abstinence and future orientation. Implications of these findings for research, prevention, and policy are discussed, emphasizing the risk of furthering

  9. We have "born digital" - now what about "born semantic"?

    Science.gov (United States)

    Leadbetter, Adam; Fredericks, Janet

    2014-05-01

    The phrase "born-digital" refers to those materials which originate in a digital form. In Earth and Space Sciences, this is now very much the norm for data: analogue to digital converters sit on instrument boards and produce a digital record of the observed environment. While much effort has been put in to creating and curating these digital data, there has been little work on using semantic mark up of data from the point of collection - what we term 'born semantic'. In this presentation we report on two efforts to expand this area: Qartod-to-OGC (Q2O) and SenseOCEAN. These projects have taken a common approach to 'born semantic': create or reuse appropriate controlled vocabularies, published to World Wide Web Commission (W3C) standards use standards from the Open Geospatial Consortium's Sensor Web Enablement (SWE) initiative to describe instrument setup, deployment and/or outputs using terms from those controlled vocabularies embed URLs from the controlled vocabularies within the SWE documents in a "Linked Data" conformant approach Q2O developed best practices examples of SensorML descriptions of Original Equipment Manufacturers' metadata (model characteristics, capabilities, manufacturer contact, etc ...) set-up and deployment SensorML files; and data centre process-lineage using registered vocabularies to describe terms (including input, output, processes, parameters, quality control flags) One Q2O use case, the Martha's Vineyard Coastal Observatory ADCP Waves instance, uses SensorML and registered vocabularies to fully describe the process of computing wave parameters from sensed properties, including quality control tests and associated results. The European Commission Framework Programme 7 project SenseOCEAN draws together world leading marine sensor developers to create a highly integrated multifunction and cost-effective in situ marine biogeochemical sensor system. This project will provide a quantum leap in the ability to measure crucial biogeochemical

  10. ROLE OF MOLECULAR MARKERS IN THYROID NODULE MANAGEMENT: THEN AND NOW.

    Science.gov (United States)

    Nikiforov, Yuri E

    2017-08-01

    To describe the evolution and clinical utility of molecular testing for thyroid nodules and cancer achieved over the last 2 decades. Scientific reports on thyroid cancer genetics and molecular diagnostics in thyroid nodules. Over the last 2 decades, our understanding of the genetic mechanisms of thyroid cancer has dramatically expanded, such that most thyroid cancers now have known gene driver events. This knowledge provides the basis for establishing and further improving molecular tests for thyroid nodules and cancer and for the introduction of new entities such as noninvasive follicular thyroid neoplasm with papillary-like nuclear features. The progress with molecular tests for thyroid nodules started in the 1990s from demonstrating feasibility of detecting various molecular alterations in fine-needle aspiration (FNA) material collected from thyroid nodules. It was followed by the introduction of the first single-gene mutational markers, such as BRAF, and a small mutational panel into clinical practice in the mid 2000s. Currently, several more advanced molecular tests are available for clinical use. They are based on multiple molecular markers and have increasing impact on the clinical management of patients with thyroid nodules. The evolution of molecular tests for thyroid nodules followed the discovery of various diagnostic and prognostic molecular markers of thyroid cancer that can be applied to thyroid FNA samples to inform more individualized management of these patients. FNA = fine-needle aspiration miRNA = micro RNA NGS = next-generation sequencing NIFTP = noninvasive follicular thyroid neoplasm with papillary-like nuclear features NPV = negative predictive value PPV = positive predictive value PTC = papillary thyroid carcinoma RAI = radioactive iodine.

  11. Pride and prejudice and zombies: The classic Regency romance—Now with ultraviolent zombie mayhem!, by Jane Austen and Seth Grahame-Smith [book review

    Directory of Open Access Journals (Sweden)

    Craig B. Jacobsen

    2009-11-01

    Full Text Available Review of Jane Austen and Seth Grahame-Smith. Pride and prejudice and zombies: The classic Regency romance—Now with ultraviolent zombie mayhem! Philadelphia, PA: Quirk Books, 2009. $12.95 (320p ISBN 978-1594743344.

  12. Assessing the ecological status in the context of the European Water Framework Directive: where do we go now?

    Science.gov (United States)

    Reyjol, Yorick; Argillier, Christine; Bonne, Wendy; Borja, Angel; Buijse, Anthonie D; Cardoso, Ana Cristina; Daufresne, Martin; Kernan, Martin; Ferreira, Maria Teresa; Poikane, Sandra; Prat, Narcís; Solheim, Anne-Lyche; Stroffek, Stéphane; Usseglio-Polatera, Philippe; Villeneuve, Bertrand; van de Bund, Wouter

    2014-11-01

    The Water Framework Directive (WFD) is now well established as the key management imperative in river basins across Europe. However, there remain significant concerns with the way WFD is implemented and there is now a need for water managers and scientists to communicate better in order to find solutions to these concerns. To address this, a Science-Policy Interface (SPI) activity was launched in 2010 led by Directorate-General for Research and Innovation and Onema (the French national agency for water and aquatic ecosystems), which provided an interactive forum to connect scientists and WFD end-users. One major aim of the SPI activity was to establish a list of the most crucial research and development needs for enhancing WFD implementation. This paper synthesises the recommendations from this event highlighting 10 priority issues relating to ecological status. For lakes, temporary streams and transitional and coastal waters, WFD implementation still suffers from a lack of WFD-compliant bioassessment methods. For rivers, special attention is required to assess the ecological impacts of hydromorphological alterations on biological communities, notably those affecting river continuity and riparian covering. Spatial extrapolation tools are needed in order to evaluate ecological status for water bodies for which no data are available. The need for more functional bioassessment tools as complements to usual WFD-compliant tools, and to connect clearly good ecological state, biodiversity and ecosystem services when implementing WFD were also identified as crucial issues. Copyright © 2014 Elsevier B.V. All rights reserved.

  13. BioTapestry now provides a web application and improved drawing and layout tools.

    Science.gov (United States)

    Paquette, Suzanne M; Leinonen, Kalle; Longabaugh, William J R

    2016-01-01

    Gene regulatory networks (GRNs) control embryonic development, and to understand this process in depth, researchers need to have a detailed understanding of both the network architecture and its dynamic evolution over time and space. Interactive visualization tools better enable researchers to conceptualize, understand, and share GRN models. BioTapestry is an established application designed to fill this role, and recent enhancements released in Versions 6 and 7 have targeted two major facets of the program. First, we introduced significant improvements for network drawing and automatic layout that have now made it much easier for the user to create larger, more organized network drawings. Second, we revised the program architecture so it could continue to support the current Java desktop Editor program, while introducing a new BioTapestry GRN Viewer that runs as a JavaScript web application in a browser. We have deployed a number of GRN models using this new web application. These improvements will ensure that BioTapestry remains viable as a research tool in the face of the continuing evolution of web technologies, and as our understanding of GRN models grows.

  14. Middle East energy megaprojects after the millennium: the need to start now

    International Nuclear Information System (INIS)

    Shammas, Pierre

    1997-01-01

    The Middle East and North Africa (MENA) region will become the heart of the world energy supply in the new millennium. Integrated energy megaprojects upon which the oil majors want to embark will be urgently needed and given typical lead times of five to ten years need to be started now. Although perhaps in the most unstable part of the energy world, MENA has the potential to become the most profitable market for such projects in the light of such factors as the security of world energy supply and the decrease in commercial oil inventories. Other considerations include the link between MENA's political stability and socio-economic reforms, and the influence of multinational organisations in promoting privatisation and structural change. A key factor is the link between the Middle East peace process and economic growth. The integrated megaprojects include the Middle East loop of gas pipelines to supply Europe and Asia. Together with the related mini independent power projects and communications links, this will raise MENA living standards and promote MENA's growing liquefied natural gas business. In the energy integration of MENA with both Europe and Asia, Turkey, Egypt, Iran and Iraq will have major roles to play. Data on MENA power requirements to 2005 and private wealth in the Arab world are appended. (2 tables). (UK)

  15. News from the Library: Springer e-books in Engineering and Mathematics - now at your desktop!

    CERN Multimedia

    CERN Library

    2013-01-01

    Users obviously expect library collections to be shaped to meet their information needs. Today, online systems have replaced the good old "Book Suggestion Register" to help readers provide libraries with input.   Moreover, e-books lend themselves by their nature to a trial period, whereby the needs and the potential usage of collections can be effectively measured. In this sense, the trial of Springer e-books on engineering done in October-November last year was extremely fruitful because it showed the interest of the community and provided us with essential feedback. Following that trial, the Library now provides access to a collection of Springer e-books on Engineering published in 2012 and 2013 and also on Mathematics (2010-2013). These collections complement the Springer Physics and Astronomy and "Lecture Notes in Physics" e-books series. As usual, your feedback is most welcome! Please contact us by e-mail.

  16. Registration, Evaluation, Authorisation, Categorisation and Tools to Evaluate Nanomaterials – Opportunities and Weaknesses (REACT NOW)

    DEFF Research Database (Denmark)

    Hansen, Steffen Foss

    have become more and more indifferent to hearing about the potential risks of NMs. Instead of implementing a regulatory framework tailored to NMs, the European Commission has initiated multiple reviews of state-of-the-scientific literature in regard to environmental, health and safety, and seems...... to be discussing the same risk assessment and regulatory challenges over and over. If history in regard to emerging risks and hazards can be used as a guide, we can now expect 15-20 years of univocal environmental, health and safety research that will not provide definitive answers but only dropwise glimpse...... of professional end-users, consumers and the environment – in that sequence – and the last two coloured bullets refer to the hazard potential for humans and the environment. The colours assigned to the exposure and hazard potential are green (•), yellow (•), red (•) and grey (•), corresponding to high, medium...

  17. Energy industry and energy policy in the Federal Republic of Germany now facing new challenges

    International Nuclear Information System (INIS)

    Ziesing, H.J.

    1986-01-01

    After the Chernobyl reactor accident, discussions about the latest deep plunge of oil prices and the consequences for the economic and energy market situation have promptly been pushed to the background, and now it is the well-known controversy about the pros and cons of the peaceful uses of nuclear energy that flares up again. The author of the paper in hand is well aware that the very complex problems posed by the task to weigh the risks of energy supply with or without nuclear energy generation can by far not be solved within this framework, so that the paper picks out only a few aspects of a decision to abandon nuclear power, and some consequences to be considered. As an introduction to the problem, the author presents a survey of the current energy situation and current energy policy, and of the related perspectives. (orig./UA) [de

  18. Royalty rules : Alberta producers are now beholden to formal regulations for reporting royalty payments to government levy collectors

    International Nuclear Information System (INIS)

    Cook, D.

    2006-01-01

    The Petroleum Marketing Regulation was established by the Alberta Department of Energy in July 2005 in order to clarify the rules governing conventional crude oil royalties. The regulation provides an incentive for industry to comply with the long-existing oil royalty reporting requirements through the addition of non-compliance penalties. An initial shadow billing system has been implemented to give industry the opportunity to understand their responsibilities and implement procedures to correct reporting and delivery inaccuracies. Battery operators in Alberta must now submit a royalty report to the Alberta Petroleum Marketing Commission on a monthly basis. The regulation provides provisions for interest charges on outstanding invoiced amounts, and formalizes existing eligibility requirements for the reimbursement of trucking costs associated with transporting the Crown's share. Penalties will be incurred if royalty reports contain erroneous information, or if the actual deliveries made are less than the prescribed royalty quantity. All penalties levied by the commission will now be sent to the battery operator in a monthly statement. Battery operators who wish to appeal their penalties may do so within 2 months after the date of the monthly statement. It was concluded that industry is not expected to experience any significant problems when the regulation comes into effect, as the 6 month shadow billing period will allow companies to make a smooth transition to the requirements of the new regulation. Details of information sessions for the new regulation were provided, as well as details of various non-compliance penalties. 1 fig

  19. Quick EXAFS experiments using a now GDA eclipse RCP GUI with EPICS hardware control

    International Nuclear Information System (INIS)

    Woolliscroft, R.J.; Coles, C.; Gerring, M.; Pearson, M.

    2012-01-01

    The Generic Data Acquisition (GDA) framework is an open source, Java and Eclipse RCP based, data acquisition software framework for synchrotron and neutron facilities. A new implementation of the GDA on the B18 X-ray beamline at the Diamond synchrotron will be discussed. This beamline performs energy scanning Xray Absorption Spectroscopy (XAS) experiments. It includes a continuous-scan mode of the monochromator synchronized with various detectors for Quick EXAFS (QEXAFS) experiments. XAS energy scans may now be performed in 30 s, where the equivalent step scans take approximately 40 minutes. A new generic perspective for the GDA client has been developed in which graphical editors are used to write XML files which hold experimental parameters. The XML files are marshalled by the GDA server to create Java beans used by Jython scripts which run on the GDA server. Underlying this, a new generic continuous scanning mechanism for the GDA has been developed. The new Eclipse RCP UI, the new continuous scanning mechanism, new hardware development and integration between the two systems shall be covered. (authors)

  20. Musculoskeletal disease and injury, now and in the future. Part 1: fractures and fatalities.

    Science.gov (United States)

    Clegg, P D

    2011-11-01

    Orthopaedic injury is common in the racing Thoroughbred and is a cause of both economic loss to the industry, as well as being an obvious welfare issue. Fatal injuries sustained during racing are an obvious major concern and it is important that all is done to reduce their frequency. As a consequence of the importance of these causes of horse morbidity and mortality, the Horserace Betting Levy Board in the UK has invested considerable resources into research in recent years in this area in an attempt to decrease the frequency of such injuries. This review summarises current knowledge relating to epidemiological investigations relating to fractures, falling and fatalities in the racing Thoroughbred. Studies identify the importance of track surface conditions, the importance of pre-existing orthopaedic pathology, as well as issues relating to the horse's past training and racing experience as important determinants of both injury and death. Such findings can now be used to develop interventions to reduce racehorse injury and death for the benefit of both the industry and the horse. © 2011 EVJ Ltd.

  1. Treating lupus in the kidney: where are we now, and where are we going?

    Science.gov (United States)

    Canetta, Pietro A A; Bomback, Andrew S; Radhakrishnan, Jai

    2011-10-01

    Kidney involvement is a frequent and dreaded consequence of systemic lupus erythematosus. While historically this condition was devastatingly morbid, over the past thirty years an improved understanding of the disease's pathobiology has accompanied increasingly effective treatment regimens that have dramatically improved the prognosis for affected patients. Induction and maintenance of remission can now be obtained in the majority of patients, although at least 20-30% may be refractory to treatment. What's more, the standard drugs in use for lupus nephritis remain fairly broad immunosuppressants, and carry notable risks and side effects. Recent years have witnessed an explosion in the number of novel immunomodulatory drugs being developed, with increasingly specific targets of action in the immune system. These molecules hold promise for a range of autoimmune disorders, including lupus nephritis, and several are already being actively investigated for that purpose. Here we review the current state of the art in the treatment of lupus nephritis, highlight the limits of standard treatments, and discuss the most promising of the novel therapies coming down the pipeline.

  2. First-Principles Computed Rate Constant for the O + O2 Isotopic Exchange Reaction Now Matches Experiment.

    Science.gov (United States)

    Guillon, Grégoire; Honvault, Pascal; Kochanov, Roman; Tyuterev, Vladimir

    2018-04-19

    We show, by performing exact time-independent quantum molecular scattering calculations, that the quality of the ground electronic state global potential energy surface appears to be of utmost importance in accurately obtaining even as strongly averaged quantities as kinetic rate constants. The oxygen isotope exchange reaction, 18 O + 32 O 2 , motivated by the understanding of a complex long-standing problem of isotopic ozone anomalies in the stratosphere and laboratory experiments, is explored in this context. The thermal rate constant for this key reaction is now in quantitative agreement with all experimental data available to date. A significant recent progress at the frontier of three research domains, advanced electronic structure calculations, ultrasensitive spectroscopy, and quantum scattering calculations, has therefore permitted a breakthrough in the theoretical modeling of this crucial collision process from first principles.

  3. Common knowledge: Now you have it, now you don`t?

    Energy Technology Data Exchange (ETDEWEB)

    Fagin, R.; Halpern, J.Y. [IBM Almaden Research Center, San Jose, CA (United States); Moses, Y. [Weizmann Institute of Science, Rehovot (Israel); Vardi, M.Y. [Rice Univ., Houston, TX (United States)

    1996-12-31

    The notion of common knowledge, where everyone knows, everyone knows that everyone knows, etc., has proven to be fundamental in various disciplines, including Philosophy, Artificial Intelligence, Economics, and Psychology. This key notion was first studied by the philosopher David Lewis in the context of conventions. Lewis pointed out that in order for something to be a convention, it must in fact be common knowledge among the members of a group. (For example, the convention that green means {open_quotes}go{close_quotes} and red means {open_quotes}stop{close_quotes} is presumably common knowledge among the drivers in our society.) Common knowledge also arises in discourse understanding. Suppose Ann asks Bob {open_quotes}What did you think of the movie?{close_quotes} referring to a showing of Monkey Business they have just seen. Not only must Ann and Bob both know that {open_quotes}the movie{close_quotes} refers to Monkey Business, but Ann must know that Bob knows, Bob must know that Ann knows that Bob knows, and so on. In fact, by a closer analysis of this situation, it can be shown that there must be common knowledge of what movie is meant in order for Bob to answer the question appropriately. Finally, common knowledge also turns out to be a prerequisite for agreement and coordinated action in distributed systems. This is precisely what makes it such a crucial notion in the analysis of interacting groups of agents. On the other hand, in practical settings common knowledge is impossible to achieve. This puts us in a somewhat paradoxical situation, in that we claim both that common knowledge is a prerequisite for agreement and coordinated action and that it cannot be attained. We discuss two answers to this paradox: Modeling the world with a coarser granularity, and relaxing the requirements for coordination.

  4. ‘..there is so much to tell now, really now'

    DEFF Research Database (Denmark)

    Balle, Søren Hattesen

    of scepticism towards continuous narrative left by modernist poetics and its emphasis on the lyrical or epiphanic moment, postmodern poetry’s reinvestment in storytelling is never made in perfectly good faith. So, if postmodern poets tell stories, they only do so by “allud[ing] to story” or “foreground...

  5. Talk | Women in STEM - Where are we now and how can we move? | 4 November

    CERN Multimedia

    2013-01-01

    "Women in science, technology, engineering and maths (STEM). Where are we now and how can we move?", by Jocelyn Bell Burnell.   Jocelyn Bell Burnell. Monday 4 November 2013, at 4.30 p.m. Globe of Science and Innovation Route de Meyrin, 1211 Genève Conference organised by the CERN Diversity Programme. English with French translation. Jocelyn Bell Burnell is a Visiting Professor at the University of Oxford. In a career spanning over four decades, she has made outstanding contributions to astronomy, the public understanding of science, in particular advancing the role of women in science, and to the promotion of physics. Working on a pioneering radio telescope as a graduate student in Cambridge in the 1960s, she made the observations that led to the discovery of pulsars. Subsequently she has performed roles in many branches of astronomy, working part-time while raising a family. Bell Burnell is a well-known figure in the public understanding of science, giving...

  6. Here and now: the intersection of computational science, quantum-mechanical simulations, and materials science

    Science.gov (United States)

    Marzari, Nicola

    The last 30 years have seen the steady and exhilarating development of powerful quantum-simulation engines for extended systems, dedicated to the solution of the Kohn-Sham equations of density-functional theory, often augmented by density-functional perturbation theory, many-body perturbation theory, time-dependent density-functional theory, dynamical mean-field theory, and quantum Monte Carlo. Their implementation on massively parallel architectures, now leveraging also GPUs and accelerators, has started a massive effort in the prediction from first principles of many or of complex materials properties, leading the way to the exascale through the combination of HPC (high-performance computing) and HTC (high-throughput computing). Challenges and opportunities abound: complementing hardware and software investments and design; developing the materials' informatics infrastructure needed to encode knowledge into complex protocols and workflows of calculations; managing and curating data; resisting the complacency that we have already reached the predictive accuracy needed for materials design, or a robust level of verification of the different quantum engines. In this talk I will provide an overview of these challenges, with the ultimate prize being the computational understanding, prediction, and design of properties and performance for novel or complex materials and devices.

  7. A Better Time Now to Consider New Reactors

    International Nuclear Information System (INIS)

    Agnihotri, Newal K.

    2004-01-01

    . Despite the challenges facing new plant development, his view is that there is not a better time than now to consider new reactors. The first, most strategic way for the government to ensure new nuclear construction is to establish a national energy platform that recognizes the contribution of nuclear power. Actions are needed too in the reactor design and regulatory process. The best-suited technology is the advanced light water reactor designs. In particular, the Westinghouse AP1000 and the General Electric ESBSW look to be the most promising. Nuclear plants can also help comply with the Kyoto protocol. It is estimated that in 2002, the 103 nuclear units in the U.S. prevented 189.5 million metric tons of carbon, 2.28 million short tons of sulfur dioxide, and 1.39 million short tons of nitrogen oxides. Additional plants only serve to increase these amounts, but all energy sources must strive toward efficiencies to ensure diversification. Future staffing issues are also a critical element for new and existing plants. Not only are nuclear engineers essential, many other skill sets are required to operate and maintain facilities. It is important that we encourage young people to study math and science and it is important that they understand the wide variety of career opportunities available within the nuclear power industry. The interview ends with comments regarding Exelon's pursuit of an early site permit (ESP)

  8. Cardiac Intensive Care Unit Management of Patients After Cardiac Arrest: Now the Real Work Begins.

    Science.gov (United States)

    Randhawa, Varinder K; Grunau, Brian E; Debicki, Derek B; Zhou, Jian; Hegazy, Ahmed F; McPherson, Terry; Nagpal, A Dave

    2018-02-01

    Survival with a good quality of life after cardiac arrest continues to be abysmal. Coordinated resuscitative care does not end with the effective return of spontaneous circulation (ROSC)-in fact, quite the contrary is true. Along with identifying and appropriately treating the precipitating cause, various components of the post-cardiac arrest syndrome also require diligent observation and management, including post-cardiac arrest neurologic injury and myocardial dysfunction, systemic ischemia-reperfusion phenomenon with potential consequent multiorgan failure, and the various sequelae of critical illness. There is growing evidence that an early invasive approach to coronary reperfusion with percutaneous coronary intervention, together with active targeted temperature management and optimization of hemodynamic, ventilator, and metabolic parameters, may improve survival and neurologic outcomes in cardiac arrest survivors. Neuroprognostication is complex, as are survivorship issues and long-term rehabilitation. Our paramedics, emergency physicians, and resuscitation specialists are all to be congratulated for ever-increasing success with ROSC… but now the real work begins. Copyright © 2017 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

  9. Wind Power Now!

    Science.gov (United States)

    Inglis, David Rittenhouse

    1975-01-01

    The government promotes and heavily subsidizes research in nuclear power plants. Federal development of wind power is slow in comparison even though much research with large wind-electric machines has already been conducted. Unless wind power programs are accelerated it will not become a major energy alternative to nuclear power. (MR)

  10. Food irradiation now

    International Nuclear Information System (INIS)

    1982-01-01

    From the start the Netherlands has made an important contribution to the irradiation of food through microbiological and toxicological research as well as through the setting-up of a pilot plant by the government and through the practical application of 'Gammaster' on a commercial basis. The proceedings of this tenth anniversary symposium of 'Gammaster' present all aspects of food irradiation and will undoubtedly help to remove the many misunderstandings. They offer information and indicate to the potential user a method that can make an important contribution to the prevention of decay and spoilage of foodstuffs and to the exclusion of food-borne infections and food poisoning in man. The book includes 8 contributions and 4 panel discussions in the field of microbiology; technology; legal aspects; and consumer aspects of food irradiation. As an appendix, the report 'Wholesomeness of irradiated food' of a joint FAO/IAEA/WHO Expert Committee has been added. (orig./G.J.P.)

  11. Why This Now

    DEFF Research Database (Denmark)

    Fausing, Bent

    2018-01-01

    There is a close relationship between the screen emergence and formation of the self, the modern self-reflective individual. The context is reflected most recently via selfies, images of the self taken with a smartphone or digital camera and posted on a social media. We are created all the time...... through technology. This is done via wearables, where we measure our heart rate, our time, our bike rides, by taking selfies, send and receive messages, pictures, smileys, SMS, MMS or using Skype. We are thus constantly in the process of creating an image of ourselves. We make a self-reflection. We...

  12. Now It's Personal

    DEFF Research Database (Denmark)

    Wilson, Douglas; Sicart (Vila), Miguel Angel

    2010-01-01

    In this paper, we introduce the concept of abusive game design as an attitude towards creating games – an aesthetic practice that operates as a critique of certain conventionalisms in popular game design wisdom. We emphasize that abusive game design is, at its core, about spotlighting the dialogic...

  13. Food irradiation - now

    International Nuclear Information System (INIS)

    Basson, R.A.

    1989-01-01

    Food irradiation technology in South Africa is about to take its rightful place next to existing food preservation methods in protecting food supplies. This is as a result of several factors, the most important of which is the decision by the Department of Health and Population Development to introduce compulsory labelling of food irradiation. The factors influencing food irradiation technology in South Africa are discussed

  14. Do It Now!

    Science.gov (United States)

    Conners, Keith J.

    1995-01-01

    One college teacher's approach to the problem of student procrastination in research paper writing has been to implement a liberal policy concerning deadlines that includes incentives for early submission of work, such as more extensive feedback and options for rewriting. The policy has had modest success and is appreciated by students for…

  15. IRAQI BUFFALO NOW

    Directory of Open Access Journals (Sweden)

    J. Kh. ALsaedy

    2010-02-01

    Full Text Available Buffaloes in Iraq represent the most productive animal since its domestication in Mesopotamia about pre-historic era recently, domesticated buffaloes all over country go through drastic factors from (1980_2006, such as (gulf wars, marsh drainage, rinder pest plaque, economic blockade which are attributed to widely changes in animal environment ,geographical sites, and dangerous decline in buffalo population accompanied by reduced fertility and feed shortage, resulted in switch of buffalo raising and started to work on another easy jobs .lastly American war in 2003 lead to marsh return and finally ethnic-fighting release, so thousands of buffalo breeders (Madan started a big mass moving from hot-spot area around Baghdad countryside villages nearer to conflicting sectors in Anbar and sallah aldin provinces towards southern marshes (natural habitats before along time. This new theater encouraged Iraqi government represented by Ministry of agriculture through three involved companies to put strategic plane for buffalo development in future.

  16. Beat Procrastination--Now!

    Science.gov (United States)

    Bakunas, Boris

    2001-01-01

    Procrastinators harbor unrealistic attitudes that promote needless delay and engender obstructive feelings such as performance anxiety, low frustration tolerance, and resentment. Common procrastination pitfalls include escapism, overpreparation, overwork, overcommitment, poor work conditions, and rationalization. Planning and prioritizing helps…

  17. Ecological Diesel Now

    International Nuclear Information System (INIS)

    Carta Petrolera

    1999-01-01

    An ACPM (Diesel) lighter and of low contained of sulfur it will begin to elaborate the refinery of Ecopetrol in Barrancabermeja (Colombia); it will be the next product of the refinery that it receives the international certification of insurance of quality ISO-9002. The new ecological product will be dedicated initially to assist the demand in Bogota. Their characteristics understand 340 degrade Celsius of final point of boil and 0, 1% in weight of sulfur, what will contribute to reduce the levels of contamination of the air in the capital. It is the result of several years of the technical personnel's of the refinery investigation, where the distillation units adapted and the advantages that they offer took advantage raw light, of low contained of sulfur and paraffin

  18. Solar Energy Now.

    Science.gov (United States)

    Rose, Harvey, Ed.

    Twenty articles addressing different aspects of solar energy are compiled in this book. They represent the views of different governmental and non-governmental organizations, members of congress, and other individuals including, for example, Barry Commoner and Amory Lovins. Topics discussed include the need for federal support, passive solar…

  19. Greek architecture now

    DEFF Research Database (Denmark)

    Skousbøll, Karin Merete

    2006-01-01

    With the author's Scandinavian viewpoint the aim of this book has been an investigation into contemporary Greek architecture and at the same time providing an understanding for its essential characteristics based on the historic, cultural heritage of Hellas.......With the author's Scandinavian viewpoint the aim of this book has been an investigation into contemporary Greek architecture and at the same time providing an understanding for its essential characteristics based on the historic, cultural heritage of Hellas....

  20. The ‘solution’ is now the ‘problem:’ wind energy, colonisation and the ‘genocide-ecocide nexus’ in the Isthmus of Tehuantepec, Oaxaca

    NARCIS (Netherlands)

    Dunlap, A.A.

    2018-01-01

    The coastal Isthmus of Tehuantepec region of Oaxaca, Mexico – known locally as the Istmo – is regarded as one of the best wind energy generating sites in the world. Marketed as a preeminent solution to mitigating climate change, wind energy is now applying increasing pressure on indigenous groups in

  1. Clean Cities Now, Vol. 20, No. 1, Summer 2016 - Tackling Transportation: Clean Cities and NPS Team Up to Steer National Parks Toward a Sustainable Future.

    Energy Technology Data Exchange (ETDEWEB)

    2016-06-01

    Clean Cities Now is the official semi-annual newsletter of Clean Cities, an initiative designed to reduce petroleum consumption in the transportation sector by advancing the use of alternative and renewable fuels, fuel economy improvements, idle-reduction measures, and new technologies, as they emerge.

  2. Exposure and Health Effects Review of Engineered Nanoscale Cerium and Cerium Dioxide Associated with its Use as a Fuel Additive - NOW IN PRINT IN THE JOURNAL

    Science.gov (United States)

    Advances of nanoscale science have produced nanomaterials with unique physical and chemical properties at commercial levels that are now incorporated into over 1000 products. Nanoscale cerium (di) oxide (Ce02) has recently gained a wide range of applications which includes coatin...

  3. What We Know Now: Synthesis for Understanding the Origin of the Pluto System

    Science.gov (United States)

    McKinnon, William B.; Stern, S. A.; Weaver, H. A.; Spencer, J. R.; Nimmo, F.; Lisse, C. M.; Umurhan, O. M.; Moore, J. M.; Buie, M. W.; Porter, S. B.; Olkin, C. B.; Young, L. A.; Ennico, K.

    2015-11-01

    The July 2015 New Horizons flyby has removed a long-standing obstacle to understanding the cosmogony of the Pluto-Charon system: the uncertain radius of Pluto. Combined with precise astrometric fits to the barycenter of the Pluto-Charon binary from HST observations of the more distant, small satellites (Brozovic et al., Icarus 246, 317-329, 2015), the densities of both Pluto and Charon are now known. At the 10% level, these densities are rather similar, as opposed to the more divergent density estimates of years past in which Charon was thought to be substantially icier. In the context of a “giant impact” origin, a rock-rich Charon implies that the precursor impacting bodies were at most only partially differentiated — possessing relatively thin ice shells (Canup, Astron. J. 141, 35, 2011). This suggests some combination of relatively slow and/or late accretion in the ancestral Kuiper belt. New Horizons has also shown that Nix and Hydra possess high albedos, consistent with ice-dominated compositions. Such compositions are consistent with a giant impact origin in which one or both precursor impacting bodies were partially differentiated, so that the small satellites ultimately formed from material ejected from ice-dominated surface layers (Peale and Canup, Treatise on Geophysics, 2nd Ed., chapter 10.17, 2015). We examine whether Pluto and Charon could actually possess the same bulk rock/ice ratio and whether this would allow for an alternate, non-giant-impact origin for the Pluto system.This work was supported by NASA's New Horizons project.

  4. Sleep Now in The Fire: An Analysis of A Song by Rage Against The Machine Using Marxism

    Directory of Open Access Journals (Sweden)

    Abdul Azis Turhan Kariko

    2011-10-01

    Full Text Available Rage against the Machine is known for their politics as well as their music, which the later helped creating an aggressive-heavy rock-rap genre. Article presents a song by Rage against the Machine band related to ideological movement in America, titled Sleep Now in the Fire. This effort brings an understanding of ideology that is embraced by the band. The method is through literature study. Presentation begins with a short biography of the band, theoretical concepts, and analysis of the song as well its music video. It is concluded that the song represents ideological criticism toward capitalism using Marxism. Both of these lyric and music video represents Marxism as it shares the same movement to fight capitalism—which in this case, Rage against the Machine is using their music, lyric, and video to fight the crime against humanity and cultural imperialism. 

  5. Should only pharmacists hold pecuniary interests in a pharmaceutical business? Attorney General (NSW) v Now.com.au Pty Ltd [2008] NSWSC 276.

    Science.gov (United States)

    Patel, Jatine; Faunce, Thomas

    2010-02-01

    The New South Wales legislature's policy of authorising only registered pharmacists to hold pecuniary interests in a pharmaceutical business is a component of Australian public health policy that accords with foundational principles and virtues of health law and bioethics. The case of Attorney General (NSW) v Now.com.au Pty Ltd [2008] NSWSC 276 considered what constitutes a pecuniary interest in this context, and how this should best be deduced from facts that may be contentious.

  6. HOMERO EN VIVO ENTONCES Y AHORA HOMER LIVE, THEN AND NOW

    Directory of Open Access Journals (Sweden)

    HÉCTOR EDUARDO GARCÍA CATALDO

    2012-01-01

    Full Text Available La obra homérica entraña una serie de cuestiones, vinculadas tanto a la tradición que ella inaugura como a la crítica que suscitó en el devenir de su propia cultura. Este artículo aborda uno de esos aspectos críticos a partir del análisis, que Platón realiza en su República, contra el contenido de los versos de la poesía homérica. La crítica platónica halla su fundamento en criterios éticos y políticos, acordes a principios racionales de acuerdo al modelo de hombre-ciudadano que el propio filósofo propone. Por consiguiente, la estética de la obra homérica no responde a ese modelo. La tachadura de los versos a este respecto significa la obliteración de lo más enigmático que hay en la naturaleza del ser humano y que mantiene en vilo su vigencia hasta hoy, que Homero avizoró con toda diafanidad y expresó con una belleza francamente inigualable, desentrañando ese humus erótico de laphysis humana, de la de entonces y aún de la de ahora.Homer's work entails a number of questions linked both to the tradition it inaugurates and to the critique it raised in the becoming of its own culture. This article studies one of those critical aspects starting from the analysis which Plato makes in his Republic against the content of the verses of Homeric poetry. Platonic criticism has its foundation in ethical and political criteria, following rational principles according to the model of citizen-man which the philosopher himself proposes. Therefore, the aesthetics of Homer's work does not respond to that model. The erasure ofthe verses in this respect means the obliteration ofwhat is most enigmatic in the nature of human beings and which keeps suspended in the air its force until today, which Homer foresaw with full diaphaneity and expressed with a beauty frankly unequaled, unraveling the erotic humus of human physis, that from then and still that from now.

  7. Prevalence of Ex Vivo High On-treatment Platelet Reactivity on Antiplatelet Therapy after Transient Ischemic Attack or Ischemic Stroke on the PFA-100(®) and VerifyNow(®).

    LENUS (Irish Health Repository)

    Kinsella, Justin A

    2012-09-12

    BACKGROUND: The prevalence of ex vivo high on-treatment platelet reactivity (HTPR) to commonly prescribed antiplatelet regimens after transient ischemic attack (TIA) or ischemic stroke is uncertain. METHODS: Platelet function inhibition was simultaneously assessed with modified light transmission aggregometry (VerifyNow; Accumetrics Inc, San Diego, CA) and with a moderately high shear stress platelet function analyzer (PFA-100; Siemens Medical Solutions USA, Inc, Malvern, PA) in a pilot, cross-sectional study of TIA or ischemic stroke patients. Patients were assessed on aspirin-dipyridamole combination therapy (n = 51) or clopidogrel monotherapy (n = 25). RESULTS: On the VerifyNow, HTPR on aspirin was identified in 4 of 51 patients (8%) on aspirin-dipyridamole combination therapy (≥550 aspirin reaction units on the aspirin cartridge). Eleven of 25 (44%) patients had HTPR on clopidogrel (≥194 P2Y12 reaction units on the P2Y12 cartridge). On the PFA-100, 21 of 51 patients (41%) on aspirin-dipyridamole combination therapy had HTPR on the collagen-epinephrine (C-EPI) cartridge. Twenty-three of 25 patients (92%) on clopidogrel had HTPR on the collagen-adenosine diphosphate (C-ADP) cartridge. The proportion of patients with antiplatelet HTPR was lower on the VerifyNow than PFA-100 in patients on both regimens (P < .001). CONCLUSIONS: The prevalence of ex vivo antiplatelet HTPR after TIA or ischemic stroke is markedly influenced by the method used to assess platelet reactivity. The PFA-100 C-ADP cartridge is not sensitive at detecting the antiplatelet effects of clopidogrel ex vivo. Larger prospective studies with the VerifyNow and with the PFA-100 C-EPI and recently released Innovance PFA P2Y cartridges (Siemens Medical Solutions USA, Inc) in addition to newer tests of platelet function are warranted to assess whether platelet function monitoring predicts clinical outcome in ischemic cerebrovascular disease.

  8. The OHS-0-0-3 form on “Identification of occupational hazards” is now available on EDH

    CERN Multimedia

    HSE Unit

    2013-01-01

    The EDH version of the OHS-0-0-3 "Identification of occupational hazards" form is now available at the following link: https://edh.cern.ch/apps/OHS.   Please remember that this form is an essential support tool for the identification of occupational hazards that employed members of the CERN personnel are exposed to during their professional activities. It serves to identify a possible need for safety training and individual protective equipment and as a guide for the CERN Medical Service for the medical follow-up of the employed members of the CERN personnel.  Whenever there is a change in working conditions and at least once a year during the MARS exercise, the supervisor and supervisee must perform a joint analysis of the supervisee’s working conditions. Following this joint analysis, a short and clear summary of the supervisees' main activities has to be written and the hazards that the supervisee is exposed to during her/his professional activit...

  9. Finnish EPR Olkiluoto 3. The world's first third-generation reactor now under construction

    International Nuclear Information System (INIS)

    2007-01-01

    The EPR was developed by Framatome and Siemens KWU (the nuclear division of Siemens), whose nuclear activities were combined in January 2001 to form Framatome ANP, now AREVA NP. The French electricity utility EDF (Electricite de France), together with the major German utilities, played an active role in the project. The safety authorities of the two countries joined forces to bring their respective safety standards into line and draw up joint design rules for the new reactor. On December 18, 2003, the consortium formed by AREVA and Siemens - and led by AREVA - signed a contract with TVO for the turnkey construction of the EPR. The overall Olkiluoto 3 project cost has been estimated by TVO at around euros 3 Billion. TVO is responsible for the overall project management and licensing process with the Finnish Safety Authority STUK. In the pre-qualification phase, STUK concluded that the EPR can meet the Finnish licensing requirements. All specific comments will be taken into account for the realization of the project. In January 2005, STUK emphasized in its safety assessment that the evolutionary EPR design compared to predecessor product lines has been further enhanced by AREVA. This paper presents first, The Finnish energy situation (Electricity consumption and supply, Finland's Kyoto CO 2 cutback, Competitiveness of nuclear power), and then the EPR in Olkiluoto (General schedule of responsibilities, Important milestones of the project). Finally, the EPR third-generation and advanced reactor is presented with its position in the international competition (Targeted design objectives, Main characteristics, competitiveness, safety, Additional measures to prevent the occurrence of events likely to damage the core, Increased protection against the consequences of core melt)

  10. Kids and adults now! Defeat Obesity (KAN-DO): rationale, design and baseline characteristics.

    Science.gov (United States)

    Ostbye, Truls; Zucker, Nancy L; Krause, Katrina M; Lovelady, Cheryl A; Evenson, Kelly R; Peterson, Bercedis L; Bastian, Lori A; Swamy, Geeta K; West, Deborah G; Brouwer, Rebecca J N

    2011-05-01

    Prevention of childhood obesity is a public health priority. Parents influence a child's weight by modeling healthy behaviors, controlling food availability and activity opportunities, and appropriate feeding practices. Thus interventions should target education and behavioral change in the parent, and positive, mutually reinforcing behaviors within the family. This paper presents the design, rationale and baseline characteristics of Kids and Adults Now! - Defeat Obesity (KAN-DO), a randomized controlled behavioral intervention trial targeting weight maintenance in children of healthy weight, and weight reduction in overweight children. 400 children aged 2-5 and their overweight or obese mothers in the Triangle and Triad regions of North Carolina are randomized equally to control or the KAN-DO intervention, consisting of mailed family kits encouraging healthy lifestyle change. Eight (monthly) kits are supported by motivational counseling calls and a single group session. Mothers are targeted during a hypothesized "teachable moment" for health behavior change (the birth of a new baby), and intervention content addresses: parenting skills ((e.g., emotional regulation, authoritative parenting), healthy eating, and physical activity. The 400 mother-child dyads randomized to trial are 75% white and 22% black; 19% have a household income of $30,000 or below. At baseline, 15% of children are overweight (85th-95th percentile for body mass index) and 9% are obese (≥ 95th percentile). This intervention addresses childhood obesity prevention by using a family-based, synergistic approach, targeting at-risk children and their mothers during key transitional periods, and enhancing maternal self-regulation and responsive parenting as a foundation for health behavior change. Copyright © 2011 Elsevier Inc. All rights reserved.

  11. Hanford to WIPP - What a Trip: The Road from Hanford is now Open

    International Nuclear Information System (INIS)

    FRENCH, M.S.

    2001-01-01

    The road leading from Hanford's Waste Receiving and Processing (WRAP) Facility to the Waste Isolation Pilot Plant (WJPP) in New Mexico developed a few bumps and detours over the past year, but it has now been successfully traversed. There were challenges obtaining Carlsbad Area Office and New Mexico Department of Ecology certification of the Hanford characterization program. After months of work, when initial certification appeared imminent, the issuance of the WIPP Hazardous Waste Permit changed the Waste Analysis Plan (WAP) required for characterizing waste for acceptance at WIPP. After a ceremony dedicating the ''Washington'' room at WIPP, the inaugural shipment from WRAP to WIPP was scheduled for June 2000. This first shipment was planned based on shipping a number of containers that had been characterized before the issuance of the WIPP Mixed Waste Permit. However, the New Mexico Department of Ecology initially declined to accept the characterization data generated before the permit was issued, necessitating revision to the planned shipment. Because of the difficulties inherent in scheduling the TRUPACT-II transport and coordination with all of the states through which the shipment would pass, it was decided to proceed with the first shipment in early July with only the drums that had been characterized after Hanford compliance with the new WIPP WAP requirements had been certified. Following the initial shipment, previously certified containers were recertified using a process approved through negotiation with the New Mexico Environment Department, and additional full shipments have been successfully completed. This paper will present an overview of the challenges overcome and lessons learned in obtaining certification, coordination with the involved states, and eventual successful1 implementation of a routine shipping program

  12. With the Advent of Tomosynthesis in the Workup of Mammographic Abnormality, is Spot Compression Mammography Now Obsolete? An Initial Clinical Experience.

    Science.gov (United States)

    Ni Mhuircheartaigh, Neasa; Coffey, Louise; Fleming, Hannah; O' Doherty, Ann; McNally, Sorcha

    2017-09-01

    To determine if the routine use of spot compression mammography is now obsolete in the assessment of screen detected masses, asymmetries and architectural distortion since the availability of digital breast tomosynthesis. We introduced breast tomosynthesis in the workup of screen detected abnormalities in our screening center in January 2015. During an initial learning period with tomosynthesis standard spot compression views were also performed. Three consultant breast radiologists retrospectively reviewed all screening mammograms recalled for assessment over the first 6-month period. We assessed retrospectively whether there was any additional diagnostic information obtained from spot compression views not already apparent on tomography. All cases were also reviewed for any additional lesions detected by tomosynthesis, not detected on routine 2-view screening mammography. 548 women screened with standard 2-view digital screening mammography were recalled for assessment in the selected period and a total of 565 lesions were assessed. 341 lesions were assessed by both tomosynthesis and routine spot compression mammography. The spot compression view was considered more helpful than tomosynthesis in only one patient. This was because the breast was inadequately positioned for tomosynthesis and the area in question was not adequately imaged. Apart from this technical error there was no asymmetry, distortion or mass where spot compression provided more diagnostic information than tomosynthesis alone. We detected three additional cancers on tomosynthesis, not detected by routine screening mammography. From our initial experience with tomosynthesis we conclude that spot compression mammography is now obsolete in the assessment of screen detected masses, asymmetries and distortions where tomosynthesis is available. © 2017 Wiley Periodicals, Inc.

  13. Now or not-now? The influence of alexithymia on intertemporal decision-making.

    Science.gov (United States)

    Scarpazza, Cristina; Sellitto, Manuela; di Pellegrino, Giuseppe

    2017-06-01

    Optimal intertemporal decisions arise from the balance between an emotional-visceral component, signaling the need for immediate gratification, and a rational, long-term oriented component. Alexithymia, a personality construct characterized by amplified sensitivity to internal bodily signals of arousal, may result in enhanced activation of the emotional-visceral component over the cognitive-rational one. To test this hypothesis, participants with high- and low-alexithymia level were compared at an intertemporal decision-making task, and their choice behavior correlated with their interoceptive sensitivity. We show that high-alexithymic tend to behave more impatiently than low-alexithymic in intertemporal decisions, particularly when the sooner reward is immediately available. Moreover, the greater their sensitivity to their own visceral sensations, the greater the impatience. Together, these results suggest a disproportionate valuation of reward available immediately in high alexithymia, possibly reflecting heightened perception of bodily physiological signals, which ultimately would bias their intertemporal decision-making. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Protest against social inequalities in B.W. Vilakazi’s poem 'Ngoba ... sewuthi' ('Because ... you now say'

    Directory of Open Access Journals (Sweden)

    N. Zondi

    2005-07-01

    Full Text Available Long before the National Party institutionalised apartheid in 1948, individuals and organisations tried to highlight the injustices of the colonial capitalist system in South Africa, but, as Lodge (1983:6 puts it, “it all ended in speeches”. This article seeks to demonstrate how Benedict Wallet Vilakazi effectively broke the silence by bringing the plight of the black masses to the attention of the world. He strongly protested against the enslavement of black labourers, especially in the gold and diamond mines, that he depicts as responsible for the human, psychological and physical destruction of the black working classes. As a self-appointed spokesperson of the oppressed, he protested against the injustices through the medium of his poetry. One of his grave concerns was the fact that black workers had been reduced to a class with no name, no rights, practically with no life and no soul. The chosen poem “Ngoba … sewuthi” (Because … you now say is thus representative of the poems in which B.W Vilakazi externalised his commitment to the well-being of the black workers, and his protest against the insensitivity of white employers.

  15. [Comment on “Unknowns about climate variability render treaty targets premature”] Time to act is now

    Science.gov (United States)

    Dickinson, Robert E.

    While I can agree with several of Singer's points, I think his discussion distorts and confuses by ignoring the more important questions to be asked. What the United States can or should do about the buildup of greenhouse gases is much more of an ethical, moral, and economic issue than one that can be answered by science alone, and thus, is rightly being decided by political processes rather than by scientific committees. We do know much more about the question of climate change from greenhouse gases than we did 20 years ago when the issue first became of major concern. Indeed, it would take thousands of pages to put down in full all the details of what we now know; and such a description would also require hundreds of pages to say what we still don't know. The past Intergovernmental Panel on Climate Change (IPCC) reports have been carefully crafted, albeit heavily abbreviated, summaries of our current scientific understanding. It is fairly certain that in another 20 years our scientific understanding will be yet much more improved, but there will also still be many important unknowns.

  16. How no-man’s-land is now everyone’s problem: the renowned Cape flora is everywhere in retreat as runaway pine invasions transform the Outeniqua and Tsitsikamma mountains

    CSIR Research Space (South Africa)

    Cowling, R

    2009-09-01

    Full Text Available hiking trails would have largely disappeared under invasive alien pines. Economic activity would flounder and poverty would increase. Such a scenario now seems a strong possibility rather than an unlikely and distant outcome, simply because society has...

  17. ESA is now a major player in global space science

    Science.gov (United States)

    1997-07-01

    longer than ISO's. Planck Surveyor was recently selected as a medium-scale project, to chart the cosmic microwave background carefully enough to trace the origin of the galaxies. ESA is now examining the option of combining these two missions in a single spacecraft, for launching in 2005. Prominent among other enticing possibilities is Mars Express, a high-level, low-cost mission that could set off for the Red Planet in 2003. It would give Europe an important stake in the exploration of Mars, by remote sensing from an orbiter and by experiments in landers. The latter can exploit ESA=s experience in preparing for the Huygens mission to Titan. Some of the Mars experiments should be readily adaptable from instruments prepared for other missions. -4- ESA is also considering SMART missions, using small satellites to test key technologies. Solar-electric propulsion, long seen as a much-needed advance in spacecraft engines, could take a small spacecraft to the Moon and then onwards to an asteroid. A second candidate for a SMART mission would develop Adrag free@ technologies for testing Einstein=s theory of gravity. Other possibilities under review include participation in a replacement for the Hubble Space Telescope, and opportunities for science associated with the International Space Station. In addition, three major projects have been selected by Europe=s space scientists as long-term goals. A spacecraft to orbit the hot planet Mercury, barely explored till now, will shed new light on the history of the Solar System. An astronomical interferometric mission using two or more telescopes in combination will observe the stars and galaxies more accurately by visible or infrared light. And a novel kind of astronomy is promised by an ambitious gravitational-wave mission to detect radiation predicted by Einstein's theory of gravity, which supposedly stretches and squeezes space itself. In short, ESA is delivering superb space science and, if future funding allows, has exciting ideas

  18. Baseline adiponectin levels do not influence the response to pioglitazone in ACT NOW.

    Science.gov (United States)

    Tripathy, Devjit; Clement, Stephen C; Schwenke, Dawn C; Banerji, MaryAnn; Bray, George A; Buchanan, Thomas A; Gastaldelli, Amalia; Henry, Robert R; Kitabchi, Abbas E; Mudaliar, Sunder; Ratner, Robert E; Stentz, Frankie B; Musi, Nicolas; Reaven, Peter D; DeFronzo, Ralph A

    2014-06-01

    Plasma adiponectin levels are reduced in type 2 diabetes mellitus (T2DM) and other insulin-resistant states. We examined whether plasma adiponectin levels at baseline and after pioglitazone treatment in impaired glucose tolerance (IGT) subjects were associated with improved insulin sensitivity (SI) and glucose tolerance status. A total of 602 high-risk IGT subjects in ACT NOW were randomized to receive pioglitazone or placebo with a median follow-up of 2.4 years. Pioglitazone reduced IGT conversion to diabetes by 72% in association with improved β-cell function by 64% (insulin secretion/insulin resistance index) and increased tissue sensitivity by 88% (Matsuda index). In pioglitazone-treated subjects, plasma adiponectin concentration increased threefold from 13 ± 0.5 to 38 ± 2.5 μg/mL (P < 0.001) and was strongly correlated with the improvement in SI (r = 0.436, P < 0.001) and modestly correlated with glucose area under the curve during oral glucose tolerance test (r = 0.238, P < 0.005) and insulin secretion/insulin resistance index (r = 0.306, P < 0.005). The increase in adiponectin was a strong predictor of reversion to normal glucose tolerance and prevention of T2DM. In the placebo group, plasma adiponectin did not change and was not correlated with changes in glucose levels. There was an inverse association between baseline plasma adiponectin concentration and progression to diabetes in the placebo group but not in the pioglitazone group. Baseline adiponectin does not predict the response to pioglitazone. The increase in plasma adiponectin concentration after pioglitazone therapy in IGT subjects is strongly related to improved glucose tolerance status and enhanced tissue sensitivity to insulin. © 2014 by the American Diabetes Association.

  19. Run for cover now or later? The impact of premiums, threats and deadlines on private health insurance in Australia.

    Science.gov (United States)

    Ellis, Randall P; Savage, Elizabeth

    2008-12-01

    Between 1997 and 2000 the Australian government introduced three policy reforms that aimed to increase private health insurance coverage and reduce public hospital demand. The first provided income-based tax incentives; the second gave an across-the-board 30% premium subsidy; and the third introduced selective age-based premium increases for those enrolling after a deadline. Together the reforms increased enrolment by 50% and reduced the average age of enrollees. The deadline appeared to induce consumers to enroll now rather than delay. We estimate a model of individual insurance decisions and examine the effects of the reforms on the age and income distribution of those with private cover. We interpret the major driver of the increased enrollment as a response to a deadline and an advertising blitz, rather than a pure price response.

  20. All Together Now: Disentangling Semantics and Pragmatics with Together in Child and Adult Language.

    Science.gov (United States)

    Syrett, Kristen; Musolino, Julien

    The way in which an event is packaged linguistically can be informative about the number of participants in the event and the nature of their participation. At times, however, a sentence is ambiguous, and pragmatic information weighs in to favor one interpretation over another. Whereas adults may readily know how to pick up on such cues to meaning, children - who are generally naïve to such pragmatic nuances - may diverge and access a broader range of interpretations, or one disfavored by adults. A number of cases come to us from a now well-established body of research on scalar implicatures and scopal ambiguity. Here, we complement this previous work with a previously uninvestigated example of the semantic-pragmatic divide in language development arising from the interpretation of sentences with pluralities and together . Sentences such as Two boys lifted a block (together) allow for either a Collective or a Distributive interpretation (one pushing event vs. two spatiotemporally coordinated events). We show experimentally that children allow both interpretations in sentences with together , whereas adults rule out the Distributive interpretation without further contextual motivation. However, children appear to be guided by their semantics in the readings they access, since they do not allow readings that are semantically barred. We argue that they are unaware of the pragmatic information adults have at their fingertips, such as the conversational implicatures arising from the presence of a modifier, the probability of its occurrence being used to signal a particular interpretation among a set of alternatives, and knowledge of the possible lexical alternatives.

  1. From Here and Now to Infinity and Eternity: A Message to New Medical Doctors*

    Science.gov (United States)

    Lapeña, José Florencio F.

    2014-01-01

    Commencement means both an end and a beginning; the end of the academic year and the beginning of the rest of your life as new physicians. For such a beginning, it is useful to view it in retrospect, from the point of view of the end, by conducting a pre-mortem on your life. Taking the existentialist (ex sistere, to stand forth) stance, each of us can be classified into one of four basic types of person, based on our characteristic space and time (or spatio-temporal) context or horizon. Our space can be limited to the “here” and our time to the “now;” or our space may extend to “infinity” and our time embark on “eternity.” In-between these poles, most have space contexts rooted in their home and work “turf” and time involving their “lifetime,” while some expand their space to include the “world” and their time to encompass “history.” From the “here and now” and “turf and lifetime” contexts, the horizons of “world and history,” and “infinity and eternity” are examined, challenging new medical doctors to realize their full potential. The new physician is exhorted not to wait for a post-mortem to define (des finitus, to set limits) his or her life. He or she should stand forth, to live, and give life. The new medical doctor is encouraged to look to the sunrise, draw strength from the sunshine, to be brave, and strong and true. PMID:24891804

  2. Estimation of basal shear stresses from now ice-free LIA glacier forefields in the Swiss Alps

    Science.gov (United States)

    Fischer, Mauro; Haeberli, Wilfried; Huss, Matthias; Paul, Frank; Linsbauer, Andreas; Hoelzle, Martin

    2013-04-01

    In most cases, assessing the impacts of climatic changes on glaciers requires knowledge about the ice thickness distribution. Miscellaneous methodological approaches with different degrees of sophistication have been applied to model glacier thickness so far. However, all of them include significant uncertainty. By applying a parameterization scheme for ice thickness determination relying on assumptions about basal shear stress by Haeberli and Hoelzle (1995) to now ice-free glacier forefields in the Swiss Alps, basal shear stress values can be calculated based on a fast and robust experimental approach. In a GIS, the combination of recent (1973) and Little Ice Age (LIA) maximum (around 1850) glacier outlines, central flowlines, a recent Digital Elevation Model (DEM) and a DEM of glacier surface topography for the LIA maximum allows extracting local ice thickness over the forefield of individual glaciers. Subsequently, basal shear stress is calculated via the rheological assumption of perfect-plasticity relating ice thickness and surface slope to shear stress. The need of only very few input data commonly stored in glacier inventories permits an application to a large number of glaciers. Basal shear stresses are first calculated for subsamples of glaciers belonging to two test sites where the LIA maximum glacier surface is modeled with DEMs derived from accurate topographic maps for the mid 19th century. Neglecting outliers, the average resulting mean basal shear stress is around 80 kPa for the Bernina region (range 25-100 kPa) and 120 kPa (range 50-150 kPa) for the Aletsch region. For the entire Swiss Alps it is 100 kPa (range 40-175 kPa). Because complete LIA glacier surface elevation information is lacking there, a DEM is first created from reconstructed height of LIA lateral moraines and trimlines by using a simple GIS-based tool. A sensitivity analysis of the input parameters reveals that the performance of the developed approach primarily depends on the

  3. The ‘solution’ is now the ‘problem:’ wind energy, colonisation and the ‘genocide-ecocide nexus’ in the Isthmus of Tehuantepec, Oaxaca

    OpenAIRE

    Dunlap, A.A.

    2018-01-01

    The coastal Isthmus of Tehuantepec region of Oaxaca, Mexico – known locally as the Istmo – is regarded as one of the best wind energy generating sites in the world. Marketed as a preeminent solution to mitigating climate change, wind energy is now applying increasing pressure on indigenous groups in the region. The article begins by outlining a definition of colonialism that assists in identifying the temporal continuity of the colonial project to understand its relationship with wind energy ...

  4. Cosmology Then and Now

    International Nuclear Information System (INIS)

    Novikov, I.D.

    1999-01-01

    In this talk a brief survey has been carried out on the development of cosmology from the days Leopold Infeld was active in the field up to the present. Attention in particular is paid to the history of our knowledge of Hubble's expansion, of the cosmological constant, of the average density of matter and its distribution, and of the related issue of possible types of matter in the Universe. (author)

  5. Where Are They Now?

    Science.gov (United States)

    Provenzano, Dominic

    1987-01-01

    Describes the current activities of 11 individuals who were prominent in the information industry at the time of Online Magazine's debut. Included are the founders of Congressional Information Service, New York Times Information Bank, Data Courier, Inc., Predicasts, Bibliographic Retrieval Services, Dialog, LEXIS and NEXIS. (EM)

  6. "Now We Have Spoken."

    Science.gov (United States)

    Zimmer, Patricia Moore

    2001-01-01

    Describes the author's experiences directing a play translated and acted in Korean. Notes that she had to get familiar with the sound of the language spoken fluently, to see how an actor's thought is discerned when the verbal language is not understood. Concludes that so much of understanding and communication unfolds in ways other than with…

  7. Breeder--now or never

    International Nuclear Information System (INIS)

    Murphy, P.M.

    1978-01-01

    The timing of the commercial introduction of the LMFBR (Liquid Metal Fast Breeder Reactor) will be an important factor in its ability to supply a significant fraction of the nation's future electrical needs. The number of breeders we can build initially will be limited by the size of our low-cost urnium resources and by the rate at which LWR's (Light Water Reactors) are placed in service. Since this uranium resource is fixed in size while electrical demand will grow geometrically, it is clear that the sooner the breeder is introduced commercially the larger will be the fraction of electrical demand that it can supply. An early commercial introduction on an adequate scale requires full-scale resumption of LWR construction and redirection of LMFBR development programs toward a near-term commercial prototype

  8. Breeder: now or never

    International Nuclear Information System (INIS)

    Murphy, P.M.

    1978-01-01

    The timing of the commercial introduction of the liquid metal fast breeder reactor (LMFBR) will be an important factor in its ability to supply a significant fraction of the nation's future electrical needs. The number of breeders we can build initially will be limited by the size of our low-cost uranium resources and by the rate at which light water reactors (LWRs) are placed in service. Since this uranium resource is fixed in size while electrical demand will grow geometrically, it is clear that the sooner the breeder is introduced commercially the larger will be the fraction of electrical demand it can supply. An early commercial introduction on an adequate scale requires full-scale resumption of LWR construction and redirection of LMFBR development programs toward a near-term commercial prototype

  9. Why Prevention? Why Now?

    Science.gov (United States)

    Tabachnick, Joan

    2013-01-01

    In 1995, the American Medical Association declared sexual abuse a "silent, violent epidemic." Since that declaration, there has been a growing acceptance and awareness of the need for a broader public health approach to preventing sexual violence. However, it is only recently that individuals and organizations are beginning to look at…

  10. Arthur Prior and 'Now'

    DEFF Research Database (Denmark)

    Blackburn, Patrick Rowan; Jørgensen, Klaus Frovin

    2016-01-01

    ’s search led him through the work of Castañeda, and back to his own work on hybrid logic: the first made temporal reference philosophically respectable, the second made it technically feasible in a modal framework. With the aid of hybrid logic, Prior built a bridge from a two-dimensional UT calculus...

  11. Anbar Awake: What Now?

    Science.gov (United States)

    2009-04-01

    enough local support in the area to prevent the AM from taking root.64 The rapid expansion of the AM was both stunning and game -changing. By...in between. 40 Oppel, “Iraq Takes Aim.” 41 Wong, al-Ansary, and Cooper, and Anna Badkhen, “We Were basically Hiring Terrorists,” Salon , August 29...www.worldthreats.com/?p=533 (accessed January 20, 2008). Badkhen, Anna. “We Were Basically Hiring Terrorists.” Salon , August 29, 2008. http://www.salon.com/news

  12. Epidemiology: Then and Now.

    Science.gov (United States)

    Kuller, Lewis H

    2016-03-01

    Twenty-five years ago, on the 75th anniversary of the Johns Hopkins Bloomberg School of Public Health, I noted that epidemiologic research was moving away from the traditional approaches used to investigate "epidemics" and their close relationship with preventive medicine. Twenty-five years later, the role of epidemiology as an important contribution to human population research, preventive medicine, and public health is under substantial pressure because of the emphasis on "big data," phenomenology, and personalized medical therapies. Epidemiology is the study of epidemics. The primary role of epidemiology is to identify the epidemics and parameters of interest of host, agent, and environment and to generate and test hypotheses in search of causal pathways. Almost all diseases have a specific distribution in relation to time, place, and person and specific "causes" with high effect sizes. Epidemiology then uses such information to develop interventions and test (through clinical trials and natural experiments) their efficacy and effectiveness. Epidemiology is dependent on new technologies to evaluate improved measurements of host (genomics), epigenetics, identification of agents (metabolomics, proteomics), new technology to evaluate both physical and social environment, and modern methods of data collection. Epidemiology does poorly in studying anything other than epidemics and collections of numerators and denominators without specific hypotheses even with improved statistical methodologies. © The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  13. Now Open for Business

    DEFF Research Database (Denmark)

    Johansson de Silva, Sara; Kokko, Ari; Norberg, Hanna

    The importance of the private sector for economic development is undisputable. Private actors - whether we talk about firms or other organizations - are an essential part of the web that forms a wellfunctioning society. However, the role of the private sector in development cooperation is more...... disputed, from proponents’ claim that supporting the growth and development of (formal) business is at the heart of what aid should do to antagonists’ view that aid could and should be used better than to increase profits for business. The present report is not about private sector development in partner......; additional (private) financial resources and innovative capacity. Potential gains for private sector actors include the emergence of new firms and markets when prohibitive risk levels are lowered through public involvement; market access and higher turnover for existing firms; and more socially responsible...

  14. TICKETS ARE NOW AVAILABLE!

    CERN Multimedia

    2000-01-01

    Replay of the Rudra-Béjart Ballet for the CERN Staff on Tuesday 5 December 2000 at 8.00 pm sharp at the Geneva ARENA This private performance will be given for you. It will last longer than the original performance at CERN: 1 hour 20 instead of 35 minutes. I encourage you all to attend this performance-bring in great numbers yourselves, members of your family, and your friends. 2,020 places are available, for which tickets will be obtained from Monday 27 November at the Staff Association Secretariat, whom I sincerely thank for having kindly accepted to distribute the tickets. To regulate the distribution, a contribution of 5 francs will be asked for each ticket: this sum is symbolic, as I intend this ballet-representation foremost as a recognition by CERN of its gratitude to you. Luciano Maiani Director-General               Dancing,      &n...

  15. Apocalypse now? not yet

    International Nuclear Information System (INIS)

    Anon.

    1999-01-01

    Physicists have proved that the fears that the new Brookhaven collider could generate destructive particles, are unfounded. They have shown that the density at the very moment of the collision will be far less than what is required to produce a black hole (by a factor 10 60 ). Another fear was the production of negative balls made up of strange quarks. This kind of quark ball would quickly grow up by absorbing any nearby positive nucleus. According to physicists this danger is not real because if such a strange quark cluster could exist, it would be necessarily positive and then harmless. (A.C.)

  16. Performance and Philosophy Now

    Directory of Open Access Journals (Sweden)

    Tasoula Kallenou

    2015-11-01

    Full Text Available Was Plato the first philosophical dramatist to explore philosophical ideas through dramatic content, introducing dramatic structures currently in line with contemporary theatre? If Plato was an influential figure for philosophers as well as theatre-makers, it can arguably be said that he was a silent pioneer in creating the newly defined discipline of Performance Philosophy. There is an obvious polarity between performance and philosophy since both disciplines are on the quest of exploring and presenting what life is. At least this can be said of ancient Greek and Roman philosophy. Conceived as “biou techne” the art of living, Greek and Roman philosophers, especially the Epicureans, Stoics and Skeptics, saw philosophy as a way of conceiving what a good life is (a life worth living and pursuing its practical realization for the attainment of eudemonia. Plato was arguably the first significant philosopher to explore philosophical ideas through dramatic content, introducing dramatic structures currently in line with contemporary theatre views. As such, he can be seen as an influential figure for theatre makers as well as for philosophers. Plato’s artistic intention was to uncover the artist that lacked substance and support the knowledgeable creative philosophical mind that besides instant emotional pleasure has to contribute in social development.

  17. Energy : branch out now

    International Nuclear Information System (INIS)

    Lebel, J.; Pluvinage, S

    2008-01-01

    This articled proposed the use of renewable energy sources to address the challenge of increasing energy demand and concerns about greenhouse gas emissions and climate change. Hydrocarbon exploitation is expected to peak by 2030, and while coal is still abundant, pollution increases with its utilization. The authors discussed the feasibility of using waste heat from industry to heat buildings. Solutions for urban traffic control were also discussed with reference to high quality public transportation, bicycle and pedestrian paths, and car pooling. Plans are underway to have about 20 hydrogen buses in circulation during the 2010 Olympic games in Whistler, British Columbia. Windpower has also become a major contender as a viable energy source, particularly with new technologies that have helped to maintain the efficiency of wind turbines. This article also discussed the use of biofuels derived from living matter. Bioenergy can be exploited from agricultural, forest or aquatic biomass. This biomass can be used to produce fuels or electricity. On a short term basis, the objective is to improve the yield of biogas, such as methane, from organic matter. The viability of deep geothermal energy was also discussed along with solar energy. Ideally, solar energy combines 3 types of technologies, notably passive, thermal and photovoltaic energy. Flexibility and affordability of materials are needed to facilitate the widespread commercialization of solar energy. The article concluded with a review of nuclear energy, which has been touted as the solution to climate change because it emits very few greenhouse gases and other atmospheric pollutants. 15 figs

  18. Censorship, Then and Now

    Science.gov (United States)

    Katz, Anne

    2018-03-01

    As I was thinking about a topic for this editorial, news and social media outlets exploded with the announcement that employees at the Centers for Disease Control and Prevention (CDC) had been instructed to not use any of seven words or phrases in budget documents (diversity, transgender, fetus, unborn child, vulnerable, evidence-
based, and science-based). To say that this hit a nerve is an understatement. My Twitter feed and email inbox filled with messages of outrage and concern, and I must admit I was swept up in the outpouring of anger. A call went out for editors of nursing journals to write editorials about this, and I was ready to do just that. 
.

  19. Stereotype, Then and Now

    Science.gov (United States)

    Nelson, Michael

    2007-01-01

    The Carlisle Indian School, founded by Richard Henry Pratt in 1879 to educate American Indian youth as an assist to having those youth success in mainstream America, is featured in two recently published books, "The Real All Americans: The Team That Changed a Game, a People, a Nation," by Sally Jenkins (Doubleday, 2007), and "Carlisle vs. Army:…

  20. Linked Library Data Now!

    Science.gov (United States)

    Singer, Ross

    2009-01-01

    There is a growing interest in making available and making sense of the data on the Web and trapped in databases. Rather than a web of unstructured documents, full of information understandable only to humans, there is a movement whose intention is to make these data structured, reusable, machine-readable, and interrelated. This approach to Web…

  1. Pneumatic Dilation of the Lower Esophageal Sphincter Can Now Be Successfully Performed Without Morbidity.

    Science.gov (United States)

    Jia, Yi; Bustamante, Marco; Moraveji, Sharareh; McCallum, Richard W

    2016-11-01

    Patients with dysphagia may be diagnosed with impaired lower esophageal sphincter (LES) relaxation and treated with pneumatic dilation (PD), stretching and tearing LES muscle fibers. Esophageal perforation has been reported to be as high as 10%. We conducted a retrospective study to evaluate the perforation rate of PD when used for impaired relaxation of the LES using current techniques. A chart review was conducted to identify patients referred for esophageal manometry by high-resolution manometry and later received PD from January 2013 to April 2016. The diagnoses of achalasia, gastroesophageal junction outlet obstruction or hypertensive LES with accompanying impaired LES relaxation were based on the Chicago Classification III. Demographic data, clinical findings, treatment approaches and outcomes were explored. A total of 187 patients were referred for dysphagia and had esophageal manometry during this time frame. In all, 62 patients (34 female), mean age of 52 years, met the criteria for incomplete relaxation of the LES and underwent a total of 88 PD procedures. All initial PD procedures used the 30-mm diameter balloon, 18 subsequently required a 35-mm balloon and 8 went on to 40-mm balloon size. No perforations or other complications were documented by esophagogastroduodenoscopy, gastrografin testing immediately postdilation or by subsequent clinical outcome. PD by an experienced gastroenterologist using general anesthesia, fluoroscopic guidance, Rigiflex balloon equipment and a specific repetitive technique can be successfully performed without perforation. Hence, the already known therapeutic efficacy of PD can now be combined with the knowledge that there is essentially no accompanying perforation rate. Copyright © 2016 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

  2. Organizational Leadership and Adaptive Reserve in Blood Pressure Control: The Heart Health NOW Study.

    Science.gov (United States)

    Henderson, Kamal H; DeWalt, Darren A; Halladay, Jacquie; Weiner, Bryan J; Kim, Jung I; Fine, Jason; Cykert, Samuel

    2018-04-01

    Our purpose was to assess whether a practice's adaptive reserve and high leadership capability in quality improvement are associated with population blood pressure control. We divided practices into quartiles of blood pressure control performance and considered the top quartile as the benchmark for comparison. Using abstracted clinical data from electronic health records, we performed a cross-sectional study to assess the association of top quartile hypertension control and (1) the baseline practice adaptive reserve (PAR) scores and (2) baseline practice leadership scores, using modified Poisson regression models adjusting for practice-level characteristics. Among 181 practices, 46 were in the top quartile, which averaged 68% or better blood pressure control. Practices with higher PAR scores compared with lower PAR scores were not more likely to reside in the top quartile of performance (prevalence ratio [PR] = 1.92 for highest quartile; 95% CI, 0.9-4.1). Similarly, high quality improvement leadership capability compared with lower capability did not predict better blood pressure control performance (PR = 0.94; 95% CI, 0.57-1.56). Practices with higher proportions of commercially insured patients were more likely than practices with lower proportions of commercially insured patients to have top quartile performance (37% vs 26%, P =.002), whereas lower proportions of the uninsured (8% vs 14%, P =.055) were associated with better performance. Our findings show that adaptive reserve and leadership capability in quality improvement implementation are not statistically associated with achieving top quartile practice-level hypertension control at baseline in the Heart Health NOW project. Our findings, however, may be limited by a lack of patient-related factors and small sample size to preclude strong conclusions. © 2018 Annals of Family Medicine, Inc.

  3. Who Are We Now Then? The Swedish Welfare State in Political Memory and Identity

    Directory of Open Access Journals (Sweden)

    Fredrik Sunnemark

    2014-03-01

    Full Text Available In the late 1980s and early 1990s the Swedish welfare state underwent a crisis which led to a transformation of society that has continued up until today. The main node of this has been an adjustment to the global ideological trend of privatization and individualism with a down-sized public sector ruled by market logic. Parallel with this Sweden has also changed from being relatively mono- cultural to becoming a more multicultural nation. Throughout these processes one constant has been how the memory of the traditional Swedish welfare state has been used and fought over by different political parties. This article deals with the struggle to appropriate this memory. The Social Democrats, in power for most of the twentieth century, are seen as the architects of the Folkhem (“The Home of the People”. But it was also the Social Democrats who – under pressure from global economy – initiated the neoliberal transformation through a series of decisions in the 1980s. Rhetorically they have treated this in two ways: one is through arguing that nothing really changed and one is through pointing out how much has changed but without acknowledging their own part in it. The ruling right-wing party The Moderates has done so through changing their rhetoric from criticizing the Social Democratic welfare state to now being the only ones representing its core values and the only ones capable of adapting them to a new situation. Furthermore, the Folkhem-metaphor has also been central for the xenophobic far-right (Sweden Democrats, claiming that the demise of the welfare state is the result of excessive immigration.

  4. Twenty years of load theory-Where are we now, and where should we go next?

    Science.gov (United States)

    Murphy, Gillian; Groeger, John A; Greene, Ciara M

    2016-10-01

    Selective attention allows us to ignore what is task-irrelevant and focus on what is task-relevant. The cognitive and neural mechanisms that underlie this process are key topics of investigation in cognitive psychology. One of the more prominent theories of attention is perceptual load theory, which suggests that the efficiency of selective attention is dependent on both perceptual and cognitive load. It is now more than 20 years since the proposal of load theory, and it is a good time to evaluate the evidence in support of this influential model. The present article supplements and extends previous reviews (Lavie, Trends in Cognitive Sciences, 9, 75-82. doi: 10.1016/j.tics.2004.12.004 , 2005, Current Directions in Psychological Science, 19, 143-148. doi: 10.1177/0963721410370295 , 2010) by examining more recent research in what appears to be a rapidly expanding area. The article comprises five parts, examining (1) evidence for the effects of perceptual load on attention, (2) cognitive load, (3) individual differences under load, (4) alternative theories and criticisms, and (5) the future of load theory. We argue that the key next step for load theory will be the application of the model to real-world tasks. The potential benefits of applied attention research are numerous, and there is tentative evidence that applied research would provide strong support for the theory itself, as well as real-world benefits related to activities in which attention is crucial, such as driving and education.

  5. The lemur revolution starts now: the genomic coming of age for a non-model organism.

    Science.gov (United States)

    Yoder, Anne D

    2013-02-01

    Morris Goodman was a revolutionary. Together with a mere handful of like-minded scientists, Morris established himself as a leader in the molecular phylogenetic revolution of the 1960s. The effects of this revolution are most evident in this journal, which he founded in 1992. Happily for lemur biologists, one of Morris Goodman's primary interests was in reconstructing the phylogeny of the primates, including the tooth-combed Lorisifomes of Africa and Asia, and the Lemuriformes of Madagascar (collectively referred to as the suborder Strepsirrhini). This paper traces the development of molecular phylogenetic and evolutionary genetic trends and methods over the 50-year expanse of Morris Goodman's career, particularly as they apply to our understanding of lemuriform phylogeny, biogeography, and biology. Notably, this perspective reveals that the lemuriform genome is sufficiently rich in phylogenetic signal such that the very earliest molecular phylogenetic studies - many of which were conducted by Goodman himself - have been validated by contemporary studies that have exploited advanced computational methods applied to phylogenomic scale data; studies that were beyond imagining in the earliest days of phylogeny reconstruction. Nonetheless, the frontier still beckons. New technologies for gathering and analyzing genomic data will allow investigators to build upon what can now be considered a nearly-known phylogeny of the Lemuriformes in order to ask innovative questions about the evolutionary mechanisms that generate and maintain the extraordinary breadth and depth of biological diversity within this remarkable clade of primates. Copyright © 2012 Elsevier Inc. All rights reserved.

  6. Mental health care reforms in Asia: the urgency of now: building a recovery-oriented, community mental health service in china.

    Science.gov (United States)

    Tse, Samson; Ran, Mao-Sheng; Huang, Yueqin; Zhu, Shimin

    2013-07-01

    For the first time in history, China has a mental health legal framework. People in China can now expect a better life and more accessible, better-quality health care services for their loved ones. Development of a community mental health service (CMHS) is at a crossroads. In this new column on mental health reforms in Asia, the authors review the current state of the CMHS in China and propose four strategic directions for future development: building on the strengths of the "686 Project," the 2004 initiative that launched China's mental health reform; improving professional skills of the mental health workforce, especially for a recovery approach; empowering families and caregivers to support individuals with severe mental illness; and using information and communications technology to promote self-help and reduce the stigma associated with psychiatric disorders.

  7. Developmental Reversals in False Memory: Now You See Them, Now You Don't!

    Science.gov (United States)

    Holliday, Robyn E.; Brainerd, Charles J.; Reyna, Valerie F.

    2011-01-01

    A developmental reversal in false memory is the counterintuitive phenomenon of higher levels of false memory in older children, adolescents, and adults than in younger children. The ability of verbatim memory to suppress this age trend in false memory was evaluated using the Deese-Roediger-McDermott (DRM) paradigm. Seven and 11-year-old children…

  8. Now you see it, now you don't: feminist training in family therapy.

    Science.gov (United States)

    Goodrich, Thelma Jean; Silverstein, Louise Bordeaux

    2005-09-01

    This article describes the state of feminist training in family therapy. Methods of assessment include questionnaires to all programs accredited by COAMFTE in universities and institutes and to leading institutes not accredited; interviews with editors of the Journal of Feminist Family Therapy; interviews with many who pioneered the feminist critique in family therapy; inspection of two major national conferences; and a search of publications. Although most program directors describe their programs as feminist and judge their training to be sufficient, their report contrasts with the perspectives of many of the journal editors and pioneers, with the small amount of training in gender issues at national conferences, and with the small number of publications. The authors offer discussion of the findings and recommendations.

  9. [Maggie's Tokyo's Human Support the Meaning of Where Now ? And Cancer Journey].

    Science.gov (United States)

    Takada, Yoshie

    2017-08-01

    The landscape architect Maggie Jencks felt that she wanted a place to "get herself back" when her breast cancer recurred and was told that she only had a few months remaining. Mr. Charles Jencks, her husband who fulfilled her wishes, opened the first "Maggie's Cancer Caring Centre" in Edinburgh in 1996. Masako Akiyama, the chief of Maggie's Tokyo found out about Maggie's Centre when she listened to a presentation from Andrew Anderson, the director of Maggie's Edinburgh, at an International Nursing Seminar in 2008. Masako Akiyama realized that support to "get back ones own power" is one of the important things. In addition, she felt that providing a "place" and "support" to patients and their families were predominant elements. When someone is diagnosed with cancer, the person gets a great shock and feels loneliness. Suddenly the person feels tomorrow will not come, every day becomes uncertain. These feelings affect their whole life such as enrollment, employment, loss of role, and change. They also affect people such as family, friends, colleagues, besides the person. Due to changes in treatment, the existential troubles that have been prolonged after the completion of the initial treatment appear. Cancer survivorship is called "Cancer journey"in the Maggie's flow. The cancer journey suddenly starts, when a person is diagnosed with cancer", without direction or a plan. Additionally, the "heart"is often left behind. To undertake the cancer journey, there are a lot of forks in the road that cannot turn back and they are urged to choose their path. "Where now ?"is a phrase in a pamphlet from Maggie's Centre, and the phrase shows that staff of Maggie's Centre can help cancer patient to recognize where they are in their Cancer journey. The Maggie's Centre has 2 important pillars: "building/environment"and "human support". As a "homely place" between hospital and my house, the building is "a healing space". Human support is provided free of charge and patients and

  10. Diabetes Incidence and Glucose Tolerance after Termination of Pioglitazone Therapy: Results from ACT NOW.

    Science.gov (United States)

    Tripathy, Devjit; Schwenke, Dawn C; Banerji, MaryAnn; Bray, George A; Buchanan, Thomas A; Clement, Stephen C; Henry, Robert R; Kitabchi, Abbas E; Mudaliar, Sunder; Ratner, Robert E; Stentz, Frankie B; Musi, Nicolas; Reaven, Peter D; DeFronzo, Ralph A

    2016-05-01

    Thiazolidinediones have proven efficacy in preventing diabetes in high-risk individuals. However, the effect of thiazolidinediones on glucose tolerance after cessation of therapy is unclear. To examine the effect of pioglitazone (PIO) on incidence of diabetes after discontinuing therapy in ACT NOW. Design, Settings and Patients: Two-hundred ninety-three subjects (placebo [PLAC], n = 138; PIO, n = 152) completed a median followup of 11.7 mo after study medication was stopped. Diabetes developed in 138 (12.3%) of PLAC vs 17 of 152 PIO patients (11.2%; P = not significant, PIO vs PLAC). However, the cumulative incidence of diabetes from start of study medication to end of washout period remained significantly lower in PIO vs PLAC (10.7 vs 22.3%; P < .005). After therapy was discontinued, 23.0% (35/152) of PIO-treated patients remained normal-glucose tolerant (NGT) vs 13.8% (19/138) of PLAC-treated patients (P = .04). Insulin secretion/insulin resistance index (I0-120/G0-120 × Matsuda index) was markedly lower in subjects with impaired glucose tolerance (IGT) who converted to diabetes during followup vs those who remained IGT or NGT. The decline in-cell function (insulin secretion/insulin resistance index) was similar in subjects with IGT who developed diabetes, irrespective of whether they were treated with PIO or PLAC. 1) The protective effect of PIO on incidence of diabetes attenuates after discontinuation of therapy, 2) cumulative incidence of diabetes in individuals exposed to PIO remained significantly (56%) lower than PLAC and a greater number of PIO-treated individuals maintained NGT after median followup of 11.4 mo, and 3) low insulin secretion/insulin resistance index is a strong predictor of future diabetes following PIO discontinuation.

  11. Taking Physics and Now the Stars on the Road With the Magic Physics Bus

    Science.gov (United States)

    Bennum, David

    2009-05-01

    In February 2003 the ``Physics on the Road'' workshop, held at Colorado State University- Fort Collins, Colorado, brought together physics faculty who were experienced in designing and providing year --round mobile physics displays and those who were interested in initiating similar outreach programs. The impetus for the workshop was the upcoming ``World Year of Physics'', but the workshop had much broader impact for many of us who attended. The University of Nevada had a long history of demonstration shows for campus visitors from K-12 students/faculty but the cost of field trips began to limit this for many schools, especially for schools in poorer neighborhoods without large scale parental fundraising. The timing of the workshop was perfect for my developing program to utilize a donated ``electric bus'' as a traveling physics demo showcase. The program has grown to near our current limitations (70 mile range of the bus and time considerations), however we are expanding the ``scope'' of the project to include evening astronomy ``star parties'' as we enter the ``Year of Astronomy''. In addition to the bus transport of portable astronomy equipment to school sites we are adding, through donation, a 22 inch telescope in a domed observatory at a secondary campus location at the edge of Reno where large scale ``star parties'' can be conducted as outreach to K-12 and the community. The ``Physics on the Road'' bus reaches several thousand elementary and middle school students every year now and the potential for similar outreach with ``Stars on the Road'' has excited several of our faculty and physics students into increased participation in these endeavors to introduce our young people to science. It has become one of our most active ``recruitment'' plans and growing numbers of local students entering physics and other science majors is anecdotal evidence of success.

  12. Evaluating change in attitude towards mathematics using the 'then-now' procedure in a cooperative learning programme.

    Science.gov (United States)

    Townsend, Michael; Wilton, Keri

    2003-12-01

    Tertiary students' attitudes to mathematics are frequently negative and resistant to change, reflecting low self-efficacy. Some educators believe that greater use should be made of small group, collaborative teaching. However, the results of such interventions should be subject to assessments of bias caused by a shift in the frame of reference used by students in reporting their attitudes. This study was designed to assess whether traditional pretest-post-test procedures would indicate positive changes in mathematics attitude during a programme of cooperative learning, and whether an examination of any attitudinal change using the 'then-now' procedure would indicate bias in the results due to a shift in the internal standards for expressing attitude. Participants were 141 undergraduate students enrolled in a 12-week statistics and research design component of a course in educational psychology. Using multivariate procedures, pretest, post-test, and then-test measures of mathematics self-concept and anxiety were examined in conjunction with a cooperative learning approach to teaching. Significant positive changes between pretest and post-test were found for both mathematics self-concept and mathematics anxiety. There were no significant differences between the actual pretest and retrospective pretest measures of attitude. The results were not moderated by prior level of mathematics study. Conclusions about the apparent effectiveness of a cooperative learning programme were strengthened by the use of the retrospective pretest procedure.

  13. Then and Now: Women Respond to the Manhattan Project - an illustrated talk

    Science.gov (United States)

    Fermi, M. A., Olivia

    2014-03-01

    I am very much looking forward to visiting you, the family of physicists gathering for your annual APS conference. In different ways, my grandfather Enrico Fermi is a member of both our families. In this sense we are connected and share a common legacy, which I want to explore from the angle of two women inextricably involved with and affected by the Manhattan Project. One from the past and one alive now. These two women, despite a significant temporal and cultural gap share a remarkable number of traits and values. My talk will not offer a particular thesis or finding. Rather it will be about ways of seeing, including questioning unnoticed assumptions and belief systems. My grandmother Laura Fermi, modeled this for me as a youngster. She was at Enrico's side during the Manhattan Project years, yet in the dark about his work. What was it like to live in a climate of intellectually and patriotically charged enthusiasm, with an undercurrent of unspoken dread? Laura, just like most everyone else, discovered the true nature of the effort on the day the atomic bomb was dropped on Hiroshima. After the war and after Enrico's untimely death in 1954, in response to all she had experienced, Laura re-invented herself as an author and visionary, pioneering in both the environmental and handgun control movements. Marian Naranjo lives on the Santa Clara Pueblo near Los Alamos. Her ancestors dwelled on the Pajarito Plateau which encompasses the space where Los Alamos National Labs (LANL) is today. Her people, the Pueblo People have used the area's natural resources for ceremonial and survival for uncountable generations. They say, ``We are this place.'' What is it like to live on land one's families have safely occupied for thousands of years, with an undercurrent of dread at the prospect of toxic waste stream products from LANL? Like my grandmother did in her place and time, Marian builds community as an integral part of her environmental and social justice activism. She is

  14. Right Here Right Now: Developing an understanding of responses to smoking policy developments using online data collection in near to real time

    Directory of Open Access Journals (Sweden)

    Gillian Fergie

    2015-10-01

    Full Text Available Background: Health policymakers require timely evidence to inform decision-making, however, rapid social change often outpaces the capacity of traditional approaches to research to produce meaningful insights. The pervasion of mobile technologies and internet access offers opportunities for capturing context specific and near real-time data on people’s perceptions, behaviours and everyday experiences that could usefully inform decision-making. The Right Here Right Now pilot study was established to provide insights into public responses to, and lived experiences of, contemporary social and health issues. From May to October 2015, a cohort of 180 adults living in Glasgow were asked weekly questions. These questions were developed with decision-makers working in health and social policy or in response to topical newsworthy public health issues that arose. The questions were delivered through an online system and allowed participants to answer directly by website, SMS or post. Aim: An issue that was of high public health policy interest and debate during this period was the need for further tobacco and nicotine control. The aim of this study was to explore the potential of using an online data collection system with a cohort of Glasgow residents to provide rapid insights into public opinion on such policy developments. Method: Three smoking/vaping related questions were sent out to Right Here Right Now participants over the course of the study. The questions were in four parts, first a multiple choice question and then three qualitative follow-up questions based on participants’ responses to part one. The questions were developed with stakeholders working in health advocacy and policy development. They focused on: perceptions of the pervasion of e-cigarettes; legislation on smoking in cars carrying children; and reflections on ten years of the ‘smoking ban’ in enclosed public places. Results: The response rate ranged from 45% to 55% (65

  15. Sprawozdanie z XII Międzynarodowej Konferencji pt. „Edukacja a nowe technologie w kulturze, informacji i komunikacji” (Toruń, 09–10.06.2015)

    OpenAIRE

    Kwiatkowska, Wioletta

    2016-01-01

    W dniach 9−10 czerwca 2015 roku odbyła się XII Międzynarodowa Konferencja Naukowa z cyklu „Technologia informacyjna w zmieniającej się edukacji”. Temat przewodni konferencji brzmiał: „Edukacja a nowe technologie w kulturze, informacji i komunikacji”. W tej edycji konferencji poruszane były zagadnienia dotyczące nowych technologii i ich znaczenie dla edukacji. Inicjatywy o takim charakterze podejmowane od kilkunastu lat przez Katedrę Dydaktyki i Mediów w Edukacji wpisały się w tradycję Wydział...

  16. The cognate advantage in bilingual aphasia: Now you see it, now you don't.

    Directory of Open Access Journals (Sweden)

    Emma Hughes

    2015-05-01

    Full Text Available Background: The role of cognateness in bilingual language production has been the focus of much investigation. Many studies have found a cognate facilitation effect for reaction times and accuracy in naming in control participants (Costa, Caramazza & Sebastien-Galles, 2000; Rosselli, Ardila, Jurado,& Salvatierra, 2012 but the findings are by no means unequivocal e.g. Siyambalapitiya et al, 2009 observed a reversal of the cognate facilitation effect in older participants. The effect of cognateness has also been investigated in aphasic participants; Roberts & Deslauriers (199 observed a strong picture naming advantage for cognate words over non-cognate words, though no individual data were reported. Several case studies have reported cognate advantage in individuals, though results vary dependent on task and on the individual (Detry, Pillon & De Partz, 2005; Lalor & Kirsner, 2001. Furthermore, an inhibitory effect for cognate words has also been observed (Tiwari & Krishnan 2015. Overall, the above findings serve to illustrate that the facilitatory effect of cognate words is uncertain, and further investigation is required. Research Question: Does task type affect the cognate advantage in Welsh-English bilingual speakers? It is expected that patients will present with a picture naming advantage for cognate items. The expectations for a cognate advantage in translation are less assured, as the presentation of a cognate word in one language may inhibit access to its translation equivalent due to the phonological overlap, or the similarity may be facilitatory in activating the phonological representation of the target. Participants: 7 Welsh-English early proficient bilingual aphasic participants were selected for participation. Each patient scored significantly lower (p<.05 than age-matched controls (N=37 on at least one task using the modified t-tests for single cases (Crawford & Howell, 1998 Methods: Picture naming and translation tasks were administered in each language. Each task included 80 items, matched across languages for frequency, word length and number of cognate items; both naming and translation probed the same words. Results and discussion: As can be seen in the Figure, the effect of cognate status was highly variable across participants, languages and tasks. Only one participant showed a robust advantage in the 4 conditions. Overall, there was little evidence for cognate facilitation in the translation task, with 4 patients even showing an inhibitory effect of cognateness. This study on an unselected group of participants suggests that cognateness effects may partly reflect a publication bias and that a full understanding of the effects of cognate status will require future investigation.

  17. I want it and I want it now: using a temporal discounting paradigm to examine predictors of consumer impulsivity.

    Science.gov (United States)

    Dittmar, Helga; Bond, Rod

    2010-11-01

    This paper proposes a new model of consumer impulsivity, using type of good, a person's endorsement of materialistic values, and identity deficits as predictors. Traditional decision making and psychological accounts see impulsive behaviour as a general overweighing of short-term gratification (I want that dress now) relative to longer-term concerns, irrespective of consumer good. Our proposal is that consumers' impulsivity (a) differs according to type of good and (b) is linked systematically to a combination of materialistic values and high identity deficits. Beginning with Study 1, three experiments, using a temporal discounting paradigm, show consistently that discount rates are higher for goods that are seen as highly expressive of identity (e.g., clothes) than goods not expressive of identity (e.g., basic body care products). For materialistic consumers, identity deficits predict discount rates for identity-expressive goods (Study 2), and discount rates change for materialistic individuals when their identity deficits are made salient (Study 3). These findings support a conceptualization of consumer impulsivity as identity-seeking behaviour.

  18. Rupture-control via T-Branches - now with precise indication of the rupture; Abrissueberwachung ueber T-Weichen mit Lokalisierung des Abrisses

    Energy Technology Data Exchange (ETDEWEB)

    Lentz, S. [Roetter Industrieelektronik GmbH, Kaiserslautern (Germany)

    2000-05-01

    In hierarchical monitoring systems, normally only the main line can be checked automatically for rupture of the sensor wire. During the AGFW lecture conference in 1998 in Essen, a solution was introduced, where through closing the branch lines with endpieces by the Roetter Industrieelektronik GmbH, the branch lines could be also monitored for ruptures automatically. This process has been further developed since then and now offers the possibility to directly indicate the ruptured branch and if there is more than one rupture, this can be indicated separately as well. (orig.) [German] In hierarchischen Ueberwachungssystemen kann ueblicherweise nur die Hauptleitung automatisch auf Abriss des Sensordrahtes geprueft werden. Bereits auf der AGFW Vortragstagung 1998 in Essen wurde eine Loesung vorgestellt, durch Abschluss der Abzweigleitungen mit Endstuecken von Roetter Industrieelektronik GmbH auch die Abzweigleitungen automatisch auf Abriss zu ueberwachen. Dieses Verfahren wurde praxisgerecht weiterentwickelt und bietet nun die Moeglichkeit, den vom Abriss betroffenen Abzweig direkt anzuzeigen, bei mehreren Abrissen ist jeder einzelne zuzuordnen. (orig.)

  19. A call to strengthen the global strategy for schistosomiasis and soil-transmitted helminthiasis: the time is now

    Science.gov (United States)

    Lo, Nathan C.; Addiss, David G.; Hotez, Peter J.; King, Charles H.; Stothard, J. Russell; Evans, Darin S.; Colley, Daniel G.; Lin, William; Coulibaly, Jean T.; Bustinduy, Amaya L.; Raso, Giovanna; Bendavid, Eran; Bogoch, Isaac I.; Fenwick, Alan; Savioli, Lorenzo; Molyneux, David; Utzinger, Jürg; Andrews, Jason R.

    2016-01-01

    Summary In 2001, the World Health Assembly (WHA) passed the landmark WHA 54.19 resolution for global scale up of mass administration of anthelminthic drugs for morbidity control of schistosomiasis and soil-transmitted helminthiasis (STH), which affect over 1.5 billion of the world's poorest people. Since then, over a decade of research and experience has yielded critical new knowledge on the control and elimination of these helminthiases. However, the global strategy has remained largely unchanged since the original 2001 WHA resolution and associated World Health Organization (WHO) guidelines on preventive chemotherapy. Here, we highlight recent advances that, taken together, support a call to revise the global strategy and guidelines for preventive chemotherapy and complementary interventions against schistosomiasis and STH. This includes the development of guidance that is specific to goals of “morbidity control” and “elimination of transmission.” We quantify the result of forgoing this opportunity by computing the yearly disease burden, mortality, and lost economic productivity associated with maintaining status quo. Without change, we estimate that the population of sub-Saharan Africa will likely lose 2.3 million disability-adjusted life years and US$3.5 billion of economic productivity every year, which is comparable to recent acute epidemics, including the 2014 Ebola and 2015 Zika epidemics. We propose that the time is now to strengthen the global strategy to address the substantial disease burden of schistosomiasis and STH. PMID:27914852

  20. A call to strengthen the global strategy against schistosomiasis and soil-transmitted helminthiasis: the time is now.

    Science.gov (United States)

    Lo, Nathan C; Addiss, David G; Hotez, Peter J; King, Charles H; Stothard, J Russell; Evans, Darin S; Colley, Daniel G; Lin, William; Coulibaly, Jean T; Bustinduy, Amaya L; Raso, Giovanna; Bendavid, Eran; Bogoch, Isaac I; Fenwick, Alan; Savioli, Lorenzo; Molyneux, David; Utzinger, Jürg; Andrews, Jason R

    2017-02-01

    In 2001, the World Health Assembly (WHA) passed the landmark WHA 54.19 resolution for global scale-up of mass administration of anthelmintic drugs for morbidity control of schistosomiasis and soil-transmitted helminthiasis, which affect more than 1·5 billion of the world's poorest people. Since then, more than a decade of research and experience has yielded crucial knowledge on the control and elimination of these helminthiases. However, the global strategy has remained largely unchanged since the original 2001 WHA resolution and associated WHO guidelines on preventive chemotherapy. In this Personal View, we highlight recent advances that, taken together, support a call to revise the global strategy and guidelines for preventive chemotherapy and complementary interventions against schistosomiasis and soil-transmitted helminthiasis. These advances include the development of guidance that is specific to goals of morbidity control and elimination of transmission. We quantify the result of forgoing this opportunity by computing the yearly disease burden, mortality, and lost economic productivity associated with maintaining the status quo. Without change, we estimate that the population of sub-Saharan Africa will probably lose 2·3 million disability-adjusted life-years and US$3·5 billion of economic productivity every year, which is comparable to recent acute epidemics, including the 2014 Ebola and 2015 Zika epidemics. We propose that the time is now to strengthen the global strategy to address the substantial disease burden of schistosomiasis and soil-transmitted helminthiasis. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Two Decades of “Horse Sweat” Taint and Brettanomyces Yeasts in Wine: Where do We Stand Now?

    Directory of Open Access Journals (Sweden)

    Manuel Malfeito-Ferreira

    2018-04-01

    Full Text Available The unwanted modification of wine sensory attributes by yeasts of the species Brettanomyces bruxellensis due to the production of volatile phenols is presently the main microbiological threat to red wine quality. The effects of ethylphenols and other metabolites on wine flavor is now recognized worldwide and the object of lively debate. The focus of this review is to provide an update of the present knowledge and practice on the prevention of this problem in the wine industry. Brettanomyces bruxellensis, or its teleomorph, Dekkera bruxellensis, are rarely found in the natural environment and, although frequently isolated from fermenting substrates, their numbers are relatively low when compared with other fermenting species. Despite this rarity, they have long been studied for their unusual metabolical features (e.g., the Custers effect. Rising interest over the last decades is mostly due to volatile phenol production affecting high quality red wines worldwide. The challenges have been dealt with together by researchers and winemakers in an effective way and this has enabled a state where, presently, knowledge and prevention of the problem at the winery level is readily accessible. Today, the main issues have shifted from technological to sensory science concerning the effects of metabolites other than ethylphenols and the over estimation of the detrimental impact by ethylphenols on flavor. Hopefully, these questions will continue to be tackled together by science and industry for the benefit of wine enjoyment.

  2. Now for the Hard Part

    DEFF Research Database (Denmark)

    Ringsmose, Jens; Rynning, Sten

    2017-01-01

    The Alliance’s success in adapting its deterrence posture has brought into focus a range of more complex challenges.......The Alliance’s success in adapting its deterrence posture has brought into focus a range of more complex challenges....

  3. Facing facts - now or never

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    Criticism is made of the British Government for failing to react to anti-nuclear public opinion following the accident at the Chernobyl reactor. The Government has renewed its commitment to nuclear power because it believes that the cheap electricity provided is necessary to maintain the standard of modern living. This article, however, says it is unnecessarily expensive, and uneconomic and an unsuitable form of energy supply. Reactor accidents are seen as inevitable and the concept of ''living safety'' with nuclear power plants is discussed. (U.K.).

  4. Concentrated solar thermal power - Now

    Energy Technology Data Exchange (ETDEWEB)

    Aringhoff, R.; Brakmann, G. [Solar Thermal Power Industry Association ESTIA, Avenue de la Fauconnerie 73, 1170 Brussels (Belgium); Geyer, M. [IEA SolarPACES Implementing Agreement, Avenida de la Paz 51, 04720 Aguadulce, Almeria (Spain); Teske, S. [Greenpeace International, Ottho Heldringstraat 5, 1066 AZ Amsterdam (Netherlands)

    2005-09-15

    This report demonstrates that there are no technical, economic or resource barriers to supplying 5% of the world's electricity needs from solar thermal power by 2040. It is written as practical blueprint to improve understanding of the solar thermal contribution to the world energy supply.

  5. Nuclear security: Then and now

    International Nuclear Information System (INIS)

    Weinstein, A.A.

    1992-01-01

    The evolution of computerized security systems at nuclear power plants has been driven by both the enhancements in computer technology and the changes in regulatory requirements over time. Technical advancements have simplified the essential nature of these systems in both real-time and data processing operations. Regulatory developments have caused a similar trend in simplification. This article addresses the computer and data acquisition portions of a security system and not the access control hardware, intrusion detection sensors, or surveillance equipment, other than to indicate how functional improvements in these areas have been achieved as systems have developed. The state of technology today includes the availability of fault-tolerant computers, the practice of networking multiple computers, and the standardization of real-time data network communications. These factors make two things possible in a plant security system. One is distributed processing, with rapid alarm annunciation (less than 1 second), essentially immediate response to access requests (less than 1 second), and an expeditious and comprehensive reporting capability. The other is permitting different plant operations (security, radiation protection, operator tours) to achieve economies by sharing the same network while using independent computers and avoiding operational conflicts

  6. Register now for ISOTDAQ 2016

    CERN Multimedia

    Markus Joos, on behalf of the organisers

    2015-01-01

    The International School of Trigger and Data Acquisition (ISOTDAQ) 2016 is the seventh in a series of International Schools dedicated to introducing MSc and PhD students to the "arts and crafts" of triggering and acquiring data for physics experiments.   The main aim of the school is to provide an overview of the basic instruments and methodologies used in high energy physics, spanning from small experiments in the lab to the very large LHC experiments, emphasising the main building blocks as well as the different choices and architectures at different levels of complexity. About half of the school time will be dedicated to laboratory exercises where the students are exposed to most of the techniques described in the lectures. The 7th International School of Trigger and Data Acquisition will be held in the Lopatie Conference Centre on the campus of the Weizmann Institute of Science in Rehovot, Israel. Lectures, hands-on exercises, breakfast, lunch and coffee break...

  7. B physics, now and future

    CERN Document Server

    CERN. Geneva

    1995-01-01

    The b-quark surprised us already twice. Unexpectedly large B-meson lifetimes told us that third generation of the quark pair mixed very little with others. The later discovery of large Bo - BO mixing showed us that the top quark mass was much larger than expected. There could be a third surprise, may be in CP violation. In this lectuere series, we quickly review the past and present of B - physics. This is followed by a more detailed discussion on future,in particular CP violation studies with future accelerators.

  8. Now and future of IAEA

    International Nuclear Information System (INIS)

    Taniguchi, Tomihiro; Omoto, Akira; Ichimura, Tomoya

    2005-01-01

    IAEA was established in 1957. Main activities consist of safeguards, cooperation of technologies and safety security. It has six sections such as the cooperation of technologies, nuclear energy, safety standards and security, nuclear science and its application, selfguards and management. Eleven Japanese are working in it and they .reported the present activities, problems and the future. Their subjects contain the problems of IAEA and expectation to Japanese, the utilization of nuclear energy, increasing nuclear safety and security in the world, application of radiation and isotope technologies, change and prospect of cooperation of technologies, and non-proliferation and safeguards. It was concluded as a first country holding many nuclear facilities that Japan had not nuclear materials and development activity in hiding and did not transform nuclear fuels reported to weapons. Accordingly, Japan is expected to make effort leading nuclear use for peace and non-proliferation in the world. (S.Y.)

  9. Plutonium Disposition Now exclamation point

    International Nuclear Information System (INIS)

    Buckner, M.R.

    1995-01-01

    A means for use of existing processing facilities and reactors for plutonium disposition is described which requires a minimum capital investment and allows rapid implementation. The scenario includes interim storage and processing under IAEA control, and fabrication into MOX fuel in existing or planned facilities in Europe for use in operating reactors in the two home countries. Conceptual studies indicate that existing Westinghouse four-loop designs can safety dispose of 0.94 MT of plutonium per calendar year. Thus, it would be possible to consume the expected US excess stockpile of about 50 MT in two to three units of this type, and it is highly likely that a comparable amount of the FSU excess plutonium could be deposed of in a few VVER-1000's. The only major capital project for this mode of plutonium disposition would be the weapons-grade plutonium processing which could be done in a dedicated international facility or using existing facilities in the US and FSU under IAEA control. This option offers the potential for quick implementation at a very low cost to the governments of the two countries

  10. Typological thinking: Then and now.

    Science.gov (United States)

    Witteveen, Joeri

    2018-05-01

    A popular narrative about the history of modern biology has it that Ernst Mayr introduced the distinction between "typological thinking" and "population thinking" to mark a contrast between a metaphysically problematic and a promising foundation for (evolutionary) biology, respectively. This narrative sometimes continues with the observation that, since the late-20th century, typological concepts have been making a comeback in biology, primarily in the context of evolutionary developmental biology. It is hard to square this narrative with the historical and philosophical literature on the typology/population distinction from the last decade or so. The conclusion that emerges from this literature is that the very distinction between typological thinking and population thinking is a piece of mere rhetoric that was concocted and rehearsed for purely strategic, programmatic reasons. If this is right, it becomes hard to make sense of recent criticisms (and sometimes: espousals) of the purportedly typological underpinnings of certain contemporary research programs. In this article, I offer a way out of this apparent conflict. I show that we can make historical and philosophical sense of the continued accusations of typological thinking by looking beyond Mayr, to his contemporary and colleague George Gaylord Simpson. I show that before Mayr discussed the typology/population distinction as an issue in scientific metaphysics, Simpson introduced it to mark several contrasts in methodology and scientific practice. I argue that Simpson's insightful discussion offers useful resources for classifying and assessing contemporary attributions of typological thinking. © 2018 The Authors. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution published by Wiley Periodicals, Inc.

  11. Czeska literatura i nowe media

    Czech Academy of Sciences Publication Activity Database

    Piorecký, Karel

    2013-01-01

    Roč. 42, č. 2013 (2013), s. 11-23 ISSN 1641-7453 R&D Projects: GA ČR GPP406/12/P603 Institutional support: RVO:68378068 Keywords : Czech literature * new media Subject RIV: AJ - Letters, Mass-media, Audiovision

  12. Where Now for Adult Learning?

    Science.gov (United States)

    Keep, Ewart; Rogers, David; Hunt, Sally; Walden, Christopher; Fryer, Bob; Gorard, Stephen; Williams, Ceri; Jones, Wendy; Hartley, Ralph

    2010-01-01

    With 6 billion British pounds of public spending reductions already on the table, and far deeper cuts inevitable, what are the prospects for adult learning in the new Parliament? Some of the regular contributors of this journal were asked what they expected and what they would like to see. Ewart Keep warns that the coalition parties' commitments…

  13. Nursing informatics: the future now.

    Science.gov (United States)

    Mamta

    2014-01-01

    Technological advancements in the health care field have always impacted the health care practices. Nursing practice has also been greatly influenced by the technology. In the recent years, use of information technology including computers, handheld digital devices, internet has advanced the nursing by bridging the gap from nursing as an art to nursing as science. In every sphere of nursing practice, nursing research, nursing education and nursing informatics play a very important role. If used properly it is a way to save time, helping to provide quality nursing care and increases the proficiency of nursing personnel.

  14. Now and future influenza vaccines.

    Science.gov (United States)

    Ruben, F L

    1990-03-01

    Influenza is a modern day plague. In the young, the clinical picture is classical, but in the elderly, the disease may go unsuspected until complications such as pneumonia develop. Influenza A and B viruses are responsible, and these viruses mutate with great regularity. Antibodies to the HA and NA surface antigens of influenza viruses, both naturally and vaccine induced, are protective. The earliest influenza vaccines were crude, toxic, and ineffective. With modern purification techniques, the egg-grown viruses have been turned into safe, immunogenic, and effective killed-virus vaccines--whole virus and split virus. Surveillance permits the correct virus strains to be incorporated into each new vaccine. Those who have been experiencing the worst effects of influenza have been identified. These individuals need to be immunized each year. In the future, live influenza virus vaccines may offer the benefits of ease of administration and longer-lasting protection. Synthetic peptides, genetically engineered antigens, and even nonantigen (anti-idiotype) vaccines are possible, but such vaccines will require adjuvant enhancement. For the present, greater efforts must be made to use existing influenza vaccines.

  15. TRANSCOM: The future is now

    International Nuclear Information System (INIS)

    Driscoll, K.L.; Hurley, J.D.; Harmon, L.H.

    1989-01-01

    All across the nation there is growing interest in the transport of materials. The issues of interest vary from finding more efficient ways to use transportation fleets to improving emergency plans for responding to situations involving potentially harmful materials. Shippers are looking for more efficient ways to keep track of their vehicles and cargo. CB radios, cellular or mobile phones, and roadside pay phones are quickly becoming outdated as the primary means of communicating with the home base. Recent trade journals, major newspapers, and transportation magazines report major trucking firms are purchasing tracking and satellite communications systems for this purpose. As reported in the Philadelphia Inquirer, High-tech space age gear is being installed in 18 wheelers to keep truckers in constant contact with their terminals and dispatchers while traveling the long, lonesome highway. There is growing interest at the State and local government level in the movement of radioactive materials across State boundaries. As a result, local government agencies are in search of better ways to prepare for and respond to emergency situations where the health or welfare of the public is perceived to be at risk. Better preparation requires prior knowledge of radioactive material shipments through the State, knowledge of the routes to be taken, and the ability to pinpoint the location of such shipments whenever necessary. For certain radioactive material shipments (e.g., High-level waste and Spent Fuel), the Nuclear Waste Policy Act (NWPA) of 1982 directs DOE to work in tandem with the States to resolve the sensitive issues of transportation

  16. Decide Now - Ditch Decision Making

    National Research Council Canada - National Science Library

    Campion, John

    2004-01-01

    .... The separation of psychology into sub-disciplines or paradigms that don't talk to one another. 3. The failure to distinguish between technical and common language usage when dealing with concepts such as decision making and command...

  17. Active Parenting Now: Program Kit.

    Science.gov (United States)

    Popkin, Michael H.

    Based largely on the theories of Alfred Adler and Rudolf Dreikurs, this parent education curriculum is a video-based interactive learning experience that teaches a comprehensive model of parenting to parents of children ages 5 to 12 years. The kit provides parents with the skills needed to help their children develop courage, responsibility, and…

  18. An Engineer Does What Now?

    Science.gov (United States)

    Gilbert, Amy; Wade, Katherine

    2014-01-01

    For an introductory engineering class at an all-girls urban high school in the Southeast, the authors planned an experience that would align with the engineering aspects of the "Next Generation Science Standards" (NGSS Lead States 2013). The goal was to better relate science, technology, engineering, and mathematics (STEM) to everyday…

  19. Concentrated solar thermal power - Now

    Energy Technology Data Exchange (ETDEWEB)

    Aringhoff, R.; Brakmann, G. [Solar Thermal Power Industry Association ESTIA, Avenue de la Fauconnerie 73, 1170 Brussels (Belgium); Geyer, M. [IEA SolarPACES Implementing Agreement, Avenida de la Paz 51, 04720 Aguadulce, Almeria (Spain); Teske, S. [Greenpeace International, Ottho Heldringstraat 5, 1066 AZ Amsterdam (Netherlands)

    2005-09-15

    This report demonstrates that there are no technical, economic or resource barriers to supplying 5% of the world's electricity needs from solar thermal power by 2040. It is written as practical blueprint to improve understanding of the solar thermal contribution to the world energy supply.

  20. Register now for ISOTDAQ 2014

    CERN Multimedia

    Markus Joos, on behalf of the organizers

    2013-01-01

    CERN is inviting final-year undergraduates, masters and PhD students studying physics, computer science and engineering to take part in the 5th International School of Trigger and Data Acquisition (ISOTDAQ2014).   The course comprises of a series of lectures and practical sessions at the Wigner Research Centre for Physics in Budapest, Hungary from 28 January to 5 February 2014. The school will cover topics from trigger electronics to data acquisition software, network architecture and more. The aim is to provide an overview of the basic instruments and methods used in high-energy physics, spanning from small experiments in lab to very large experiments at the Large Hadron Collider (LHC). The concepts taught also apply to fields outside high-energy physics, such as data acquisition in astrophysics. The Wigner Centre recently became a major extension of CERN's computing facilities, hosting an extension of Tier 0 activities of the Worldwide LHC Computing Grid. Please note that th...

  1. Standby: where are we now?

    International Nuclear Information System (INIS)

    Meier, Alan

    2005-01-01

    Organised efforts to measure and reduce standby power use have been under way for about a decade. Recent measurements of homes in developed countries show that standby ranges from 60 to 110 W per home, which corresponds to about 4-11% of residential electricity use. Standby in most European homes lies between 50 W and 70 W, with countries such as Denmark at the higher end and Greece at the lower end. Some evidence suggests that these levels have risen rapidly in the past few years as a result of purchases of computers, set-top boxes, and digital appliances. Few data exist for commercial or industrial buildings but standby may be as much as 0.7 W/m 2 of floor area. About ten voluntary programmes to reduce standby are under way around the world. Three mandatory programmes to limit standby are already scheduled to go into force in 2006-2008, with others likely to follow. A horizontal standard limiting standby in all products would appear to be the most sensible policy but the rising energy use in other low-power modes must also be addressed

  2. Can you hear me now?

    Science.gov (United States)

    Shacham, Enbal; Stamm, Kate E.; Overton, Edgar T.

    2013-01-01

    Recent studies support technology-based behavioral interventions for individuals with HIV. This study focused on the use of cell phone and internet technologies among a cohort of 515 HIV-infected individuals. Socio-demographic and clinic data were collected among individuals presenting at an urban Midwestern university HIV clinic in 2007. Regular internet usage occurred more often with males, Caucasians, those who were employed, had higher salaries, and were more educated. Higher levels of education and salary >$10,000 predicted regular usage when controlling for race, employment, and gender. Cell phone ownership was associated with being Caucasian, employed, more educated, and salary > $10,000. Employment was the only predictor of owning a cell phone when controlling for income, race, and education. Individuals who were educated were more likely to know how to text message. Employment and post-high school education predicted knowledge of text messaging, when controlling for age. Disparities among internet, cell phone, and text messaging usage exist among HIV-infected individuals. PMID:20024756

  3. Transformational electronics are now reconfiguring

    KAUST Repository

    Rojas, Jhonathan Prieto; Hussain, Aftab M.; Carreno, Armando Arpys Arevalo; Foulds, I. G.; Sevilla, Galo T.; Nassar, Joanna M.; Hussain, Muhammad Mustafa

    2015-01-01

    enhanced electronic systems for application in entertainment, healthcare, fitness and wellness, military and manufacturing industry. Based on these novel structural designs we have developed a siliconbased network of hexagonal islands connected through

  4. Molecular replacement then and now

    International Nuclear Information System (INIS)

    Scapin, Giovanna

    2013-01-01

    A brief overview, with examples, of the evolution of molecular-replacement methods and models over the past few years is presented. The ‘phase problem’ in crystallography results from the inability to directly measure the phases of individual diffracted X-ray waves. While intensities are directly measured during data collection, phases must be obtained by other means. Several phasing methods are available (MIR, SAR, MAD, SAD and MR) and they all rely on the premise that phase information can be obtained if the positions of marker atoms in the unknown crystal structure are known. This paper is dedicated to the most popular phasing method, molecular replacement (MR), and represents a personal overview of the development, use and requirements of the methodology. The first description of noncrystallographic symmetry as a tool for structure determination was explained by Rossmann and Blow [Rossmann & Blow (1962 ▶), Acta Cryst.15, 24–31]. The term ‘molecular replacement’ was introduced as the name of a book in which the early papers were collected and briefly reviewed [Rossmann (1972 ▶), The Molecular Replacement Method. New York: Gordon & Breach]. Several programs have evolved from the original concept to allow faster and more sophisticated searches, including six-dimensional searches and brute-force approaches. While careful selection of the resolution range for the search and the quality of the data will greatly influence the outcome, the correct choice of the search model is probably still the main criterion to guarantee success in solving a structure using MR. Two of the main parameters used to define the ‘best’ search model are sequence identity (25% or more) and structural similarity. Another parameter that may often be undervalued is the quality of the probe: there is clearly a relationship between the quality and the correctness of the chosen probe and its usefulness as a search model. Efforts should be made by all structural biologists to ensure that their deposited structures, which are potential search probes for future systems, are of the best possible quality

  5. Climate change: where to now?

    International Nuclear Information System (INIS)

    Pearman, Graeme

    2007-01-01

    Full text: Full text: The potential for human impact on global climate arose out of an understanding developed in the 19th century of the physical conditions influencing global temperatures. In the past three decades, observations and improved understanding of climate processes have led to the conclusions that the planet has warmed, this warming has been primarily due to increases of atmospheric greenhouse gases and that this has been due to human activities. But our knowledge is incomplete. The management of the risks associated with future climate change demands improvement of the knowledge base. Specific areas for improvement include the: role of aerosols in the amelioration or otherwise of warming trends; potential instability of systems, e.g. the deglaciation of Greenland that could lead to rapid destabilisation of climate; response of biological systems to climate change, their phrenology, behaviour, genetics and dispersion; opportunities for cost-effective managed adaptation; and improved technologies for meeting the energy demands. Climate science has been characterised by a level of integration of disciplinary fields uncommon in other areas. Yet the nature of the climate system, its diverse impacts and the range of mitigation options suggests that while disciplinary endeavours need to continue, further integration is required. Policy development requires the exploration of options that respect the complexity of climate and its impacts but also the pluralistic aspirations of societies. The 21st century should be characterised by considered, inclusive and strategic policy development. For science to contribute to this process, much more attention is needed to the processes involved in the exchange of knowledge between the scientific community and those who develop public or private policy. A new engagement and shared understanding of the potential role of science in modern societies, particularly with respect to climate change, is an essential component of the future management of climate change. This engagement requires attention to counter-productive trends such as the: dominance of the purchaser-provider model for knowledge generation; emphasis on accountability over innovation; emphasis on wealth generation rather than the broader spectrum of human aspirations; and emergence of political interference, ideologically-based constraints, short-termism, and the so called 'non-reality' world. Even with attention to these broad-ranging demands, one further and perhaps more demanding aspect requires attention. This is the question of human governance, structures and procedures. We have seen significant delays between the development of knowledge concerning climate change and policy response. These delays may have serious implications for future generations

  6. Transformational electronics are now reconfiguring

    KAUST Repository

    Rojas, Jhonathan Prieto

    2015-05-22

    Current developments on enhancing our smart living experience are leveraging the increased interest for novel systems that can be compatible with foldable, wrinkled, wavy and complex geometries and surfaces, and thus become truly ubiquitous and easy to deploy. Therefore, relying on innovative structural designs we have been able to reconfigure the physical form of various materials, to achieve remarkable mechanical flexibility and stretchability, which provides us with the perfect platform to develop enhanced electronic systems for application in entertainment, healthcare, fitness and wellness, military and manufacturing industry. Based on these novel structural designs we have developed a siliconbased network of hexagonal islands connected through double-spiral springs, forming an ultra-stretchable (~1000%) array for full compliance to highly asymmetric shapes and surfaces, as well as a serpentine design used to show an ultrastretchable (~800%) and flexible, spatially reconfigurable, mobile, metallic thin film copper (Cu)-based, body-integrated and non-invasive thermal heater with wireless controlling capability, reusability, heating-adaptability and affordability due to low-cost complementary metal oxide semiconductor (CMOS)-compatible integration. © (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.

  7. Climate Action: Now or Never

    International Nuclear Information System (INIS)

    Auverlot, Dominique; Beeker, Etienne; Venturi, Richard

    2016-04-01

    The success of the Paris Agreement in rallying the world to take collective action against climate change and global warming has highlighted the stark challenge that lays ahead: Humankind must achieve a net zero carbon emissions target by the second half of this century. If the goal of keeping warming within 2 deg. C is to be met, all countries will have to reduce their greenhouse gas (GHG) emissions by about 30% more than the amount that was pledged in the run-up to the Paris conference in December 2015. This makes the action taken over the next decade absolutely critical in reaching this goal. The fact that affordable fossil fuels are likely to remain readily available is certain to complicate this collective effort even further. Together with the US and China, the European Union will have to go beyond its goal of reducing its emissions by 40% of its 1990 levels by 2030. This means it will have to both lower its consumption of fossil fuels - coal in particular - and create a credible carbon price signal for its economy by establishing a floor price in its Emissions Trading System (ETS) and possibly a European carbon tax. France, for its part, must concentrate on reducing emissions from transport, residential and commercial housing and agriculture as its emissions from electricity generation are already very low. Having brought down its emissions by close to 19% since 1990, France is clearly committed to taking climate action. The economic crisis notwithstanding, this reduction comes mostly from the manufacturing sector and energy production itself. However, if the country is to reach carbon neutrality by the second half of the 21. century without hampering its competitiveness, it will have to rethink the scope and rate of action to be taken. (authors)

  8. Flashforward: the future is now

    NARCIS (Netherlands)

    Pisters, P.

    2011-01-01

    In The Future of the Image (2007) Jacques Rancière states that the end of images is behind us. He argues for an aesthetics of the image that acknowledges the continuing power of images as educating documentations of traces of history, as directly affecting interruptions, and as open-to-combining

  9. Register now for ISOTDAQ 2017

    CERN Multimedia

    Hannes Sakulin, on behalf of the organisers

    2016-01-01

    The International School of Trigger and Data Acquisition (ISOTDAQ) 2017 is the eighth in a series of International Schools dedicated to introducing MSc and PhD students to the "arts and crafts" of triggering and acquiring data for physics experiments.   The main aim of the school is to provide an overview of the basic instruments and methodologies used in high energy physics, spanning from small experiments in the lab to the very large LHC experiments, emphasising the main building blocks as well as the different choices and architectures at different levels of complexity. About half of the school time will be dedicated to laboratory exercises where the students are exposed to most of the techniques described in the lectures. The 8th International School of Trigger and Data Acquisition will be held in the Amsterdam Science Park at Nikhef (the National Institute for Sub-atomic physics) Amsterdam, The Netherlands. Lectures, the hands on exercises, breakfast, lunch and coffee breaks ...

  10. Telecommunications Is Here and Now.

    Science.gov (United States)

    Clark, Chris

    1988-01-01

    Presents an overview of telecommunications and its use in the field of education. Topics discussed include conferencing, electronic messaging, distance learning, networking, database searching, and projects relating to educational telecommunications sponsored by the International Council for Computers in Education (ICCE). (LRW)

  11. The dance of the now

    DEFF Research Database (Denmark)

    Engel, Lis

    2008-01-01

    and meaning. How are embodiment as performance of expressive form and cultural identities interwoven? How are intersubjectivity and culture performed? The living body images are analysed from an aesthetic-phenomenological perspective highlighting the living body as an inter-subjective, "vibrational" field......The inspiration for this paper comes from an interest in the living movement of everyday life and from an interest in the stories of the felt sense of embodiment, subjectivity and culture. A phenomenological approach is used to get an embodied and experiential understanding of sensitive form...

  12. Now We're Really Clicking!

    Science.gov (United States)

    Popelka, Susan R.

    2010-01-01

    Interactive response systems go by a multitude of names--clickers, polling devices, automatic hand raisers, "those cell phone thingies." In this article, the author describes how she used a clicker with her precalculus students. The clicker is one of several types widely used in K-12 classrooms, each of which has its own variety of features and…

  13. X is now a meme

    DEFF Research Database (Denmark)

    Konzack, Lars

    2012-01-01

    Internet-memer er den nye globale, lynhurtige og indforståede folklore. Det er sjovt, det er frækt, det er sukkersødt, det er klamt, det er oprørsk, og det er lige nu på vej til en af dine digitale enheder. Her kommer en analyse af fænomenet....

  14. Lattice sums then and now

    CERN Document Server

    Borwein, J M; McPhedran, R C

    2013-01-01

    The study of lattice sums began when early investigators wanted to go from mechanical properties of crystals to the properties of the atoms and ions from which they were built (the literature of Madelung's constant). A parallel literature was built around the optical properties of regular lattices of atoms (initiated by Lord Rayleigh, Lorentz and Lorenz). For over a century many famous scientists and mathematicians have delved into the properties of lattices, sometimes unwittingly duplicating the work of their predecessors. Here, at last, is a comprehensive overview of the substantial body of

  15. Now, Here's the Weather Forecast...

    Science.gov (United States)

    Richardson, Mathew

    2013-01-01

    The Met Office has a long history of weather forecasting, creating tailored weather forecasts for customers across the world. Based in Exeter, the Met Office is also home to the Met Office Hadley Centre, a world-leading centre for the study of climate change and its potential impacts. Climate information from the Met Office Hadley Centre is used…

  16. Where now for schizophrenia research?

    Science.gov (United States)

    Nutt, David J; Need, Anna C

    2014-08-01

    Schizophrenia continues to pose a serious challenge to neuroscience and psychiatry as well as to health care systems and to the patients and families who suffer this terrible and disabling illness. Major developments in the past few months in both genetics and drug development oblige us to consider novel drug discovery tactics for future schizophrenia research. Here we review what we consider to be the key issues and some suggested solutions. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

  17. Now, think again about adaptation

    Energy Technology Data Exchange (ETDEWEB)

    Tarlock, A [Chicago-Kent College of Law (USA)

    1992-01-01

    The paper concentrates on three problems with adaptation to global warming that are often overlooked. First, adaptation is based on the ideology of scientific progress, a faith that is open to question. Second, the degree of friction in the proposed institutional responses is often underestimated so institutions may not perform as expected. Third, many institutions have no fair and adequate mechanism to deal with global warming. In these cases, adaptation is the adoption of a no action strategy. The philosophical basis for the first objection is discussed. Then the second and third objections are illustrated with two problems: the reallocation of western water and the use of land use controls to protect coastal and inland areas from the adverse consequences of global climate change. 63 refs.

  18. Persistent pain in the older adult: what should we do now in light of the 2009 American geriatrics society clinical practice guideline?

    Science.gov (United States)

    Katz, James D; Shah, Tina

    2009-12-01

    The recent publication of revised guidelines for the management of persistent pain in the older adult (American Geriatric Society, 2009) has posed a dilemma for clinicians. In essence, these revised guidelines now downplay the use of nonsteroidal anti-inflammatory drugs (NSAIDs) relative to prior year's recommendations. The strong recommendation for caution when employing NSAIDs is because of the numerous, well-documented, potential adverse effects including renal failure, stroke, hypertension, heart failure exacerbations, and gastrointestinal complications. Nevertheless, physicians still have a substantial arsenal for combating chronic pain due to such conditions as degenerative arthritis and back problems. Options for intervention include physical therapy, topical nonsteroidals, capsaicin, topical lidocaine, intra-articular therapies, and judicious use of narcotics. In the future, cyclooxygenase-inhibiting nitric oxide-donating drugs may represent a technical improvement in the toxicity profile of traditional NSAIDs.

  19. Vanishing bone disease of the orbital roof: now you see it, now you don't

    International Nuclear Information System (INIS)

    Dharsono, Ferry; Van Heerden, Jolandi; McAuliffe, William; Ardakani, Nima M.; Franconi, Catherine; Honeybul, Stephen; Lind, Christopher R.

    2014-01-01

    We describe a rare case of vascularised orbital roof and calvarial erosions with an associated venous malformation. In the absence of infection, malignancy, trauma and eosinophillic granuloma, the closest previously described entity is vanishing bone disease. Computed tomography (CT), MRI, catheter angiography and pathology were all important in the diagnostic workup to enable surgical planning for biopsy and reconstruction. Ongoing CT and MRI follow-up imaging will determine future treatment planning.

  20. Now You Hear It, Now You Don't: Vowel Devoicing in Japanese Infant-Directed Speech

    Science.gov (United States)

    Fais, Laurel; Kajikawa, Sachiyo; Amano, Shigeaki; Werker, Janet F.

    2010-01-01

    In this work, we examine a context in which a conflict arises between two roles that infant-directed speech (IDS) plays: making language structure salient and modeling the adult form of a language. Vowel devoicing in fluent adult Japanese creates violations of the canonical Japanese consonant-vowel word structure pattern by systematically…

  1. Practice Facilitator Strategies for Addressing Electronic Health Record Data Challenges for Quality Improvement: EvidenceNOW.

    Science.gov (United States)

    Hemler, Jennifer R; Hall, Jennifer D; Cholan, Raja A; Crabtree, Benjamin F; Damschroder, Laura J; Solberg, Leif I; Ono, Sarah S; Cohen, Deborah J

    2018-01-01

    Practice facilitators ("facilitators") can play an important role in supporting primary care practices in performing quality improvement (QI), but they need complete and accurate clinical performance data from practices' electronic health records (EHR) to help them set improvement priorities, guide clinical change, and monitor progress. Here, we describe the strategies facilitators use to help practices perform QI when complete or accurate performance data are not available. Seven regional cooperatives enrolled approximately 1500 small-to-medium-sized primary care practices and 136 facilitators in EvidenceNOW, the Agency for Healthcare Research and Quality's initiative to improve cardiovascular preventive services. The national evaluation team analyzed qualitative data from online diaries, site visit field notes, and interviews to discover how facilitators worked with practices on EHR data challenges to obtain and use data for QI. We found facilitators faced practice-level EHR data challenges, such as a lack of clinical performance data, partial or incomplete clinical performance data, and inaccurate clinical performance data. We found that facilitators responded to these challenges, respectively, by using other data sources or tools to fill in for missing data, approximating performance reports and generating patient lists, and teaching practices how to document care and confirm performance measures. In addition, facilitators helped practices communicate with EHR vendors or health systems in requesting data they needed. Overall, facilitators tailored strategies to fit the individual practice and helped build data skills and trust. Facilitators can use a range of strategies to help practices perform data-driven QI when performance data are inaccurate, incomplete, or missing. Support is necessary to help practices, particularly those with EHR data challenges, build their capacity for conducting data-driven QI that is required of them for participating in practice

  2. It is now time to proceed with a gas-cooled breeder reactor (GBR) demonstration plant

    International Nuclear Information System (INIS)

    Chermanne, J.

    1976-01-01

    Since 1969, the GBRA has been making studies to provide evidence on questions which were not clear regarding the Gas-cooled Breeder Reactor: design feasibility and performance, safety, strategy and economics, and R and D necessary for a demonstration plant. Studies were carried out on a 1200-MW(e) commercial reference design with pin fuel, which was also used as a basis for a definition of the GBR demonstration plant. During the six years, a great deal of information has been generated at GBRA and it confirms the forecasts of the promoters of the Gas-cooled Breeder Reactor that the GBR is an excellent reactor from all points of view: design - the reactor can be engineered without major difficulty, using present techniques. As far as fuel is concerned, LMFBR fuel technology is applicable plus limited specific development effort. Performance - the GBR is the best breeder with oxide fuel and using conventional techniques. The strategy studies carried out at GBRA have clearly shown that a high performance breeder such as the GBR is absolutely required in large quantities by the turn of the century in order to avoid dependence on natural uranium resources. Regarding safety, a major step forward has been made when an ad hoc group on GBR safety, sponsored by the EEC, concluded that no major difficulties were anticipated which would prevent the GBR reaching adequate safety standards. Detailed economic assessments performed on an item-to-item basis have shown that the cost of a GBR with its high safety standard is about the same as that of an HTR. One can therefore conclude that, with the present cost of natural uranium, the GBR is competitive with the LWRs. Owing to the very limited R and D effort necessary and the obvious safety, economic and strategic advantages of the concept, it is concluded that the development and construction of a GBR demonstration plant must be started now if one wants to secure an adequate energy supply past the turn of the century. (author)

  3. From Epicurus to Maslow: Happiness Then and Now and the Place of the Human Being in Social Theory

    Directory of Open Access Journals (Sweden)

    Gerald Gutenschwager

    2013-05-01

    Full Text Available Protagoras said, "The human being is the measure of all things". This implies, among other things, that language, science and religion are human inventions, as are economics, money, efficiency, race, conflict, etc. As symbol-using animals, we have created these concepts to serve our purposes. But as our societies have increased in size and our concepts have become more abstract, there is a danger that we will forget our authorship and reify these symbols. This inhibits change in the way we name things, so we are always in danger of misunderstanding the reality we are describing. We seem to be at such a stage now as we employ 18th and 19th century theories to describe and, more importantly, create 21st century reality. One such idea has to do with human needs. Influenced by the abstract (economic concepts we use, we have lost our sense of what we truly need. Epicurus and Maslow may help to review and reassess those concepts. Epicurus, by suggesting that our material needs are quite simple but that emotional and spiritual need satisfaction requires a small scale loving community, free from fear, and Maslow, by suggesting that our emotional development is age-related, which, besides therapy, may help in suggesting revisions in socioeconomic theory that would ensure the social conditions that would allow this development to take place successfully.

  4. NucNet's growing impact on the media - Now the official figures

    International Nuclear Information System (INIS)

    Ashton, Jack; Lewis, Chris

    1998-01-01

    Net's impact on the news media has had to be almost completely anecdotal. Now, thanks to a comparatively new database search facility, the NucNet Central Office team is able to track instances in which NucNet has been quoted as the source for a news story or magazine article. The database is run by Reuters, but contains information from a wide range of other news sources, such as national news agencies and major national newspapers. A search of the database, carried out on December 10th 1997, produced 42 cases of NucNet being quoted by name over the previous three years. There were five in 1995, 13 in 1996, and 24 in 1997. No fewer than 15 of the 24 cases in 1997 occurred in the preceding six months. It takes no great mathematician to see that each annual figure is roughly double that of the preceding 12-month period. We can at least see every instance of NucNet being quoted by Reuters, but this of course does not cover the other major international news agencies, such as the Associated Press, UPI and AFP. This underlines the fact that NucNet Central Office and the NucNet Board rely heavily on individual network members spontaneously reporting examples of media use. The results obtained recently, showing regular and fairly frequent use by Reuters and the print media, but the figures do not give the full picture. If the database, known as Reuters Business Briefing, acts as some sort of barometer measuring NucNet's impact on the news media, we cannot say exactly what the weather is like - but at least we can say that the barometer reading is on the increase. And for once we can give definite figures. (author)

  5. What is the destiny of a threatened fish, Ptychobarbus chungtienensis, now that non-native weatherfishes have been introduced into Bita Lake, Shangri-La?

    Science.gov (United States)

    Jiang, Wan-Sheng; Qin, Tao; Wang, Wei-Ying; Zhao, Ya-Peng; Shu, Shu-Sen; Song, Wei-Hong; Chen, Xiao-Yong; Yang, Jun-Xing

    2016-09-18

    Biological invasion is a pervasive negative force of global change, especially in its effects on sensitive freshwater ecosystems. Even protected areas are usually not immune. Ptychobarbus chungtienensis is a threatened freshwater fish now almost confined to Bita Lake, in the Shangri-La region of Yunnan province, China. Its existence is threatened by the introduction of non-native weatherfishes (Misgurnus anguillicaudatus and Paramisgurnus dabryanus) by an unusual method known as 'prayer animal release'. Periodic surveys revealed the ratio of invasive weatherfishes to P. chungtienensis has been increasing since the former species was first recorded from the lake in August, 2009. Ptychobarbus chungtienensis shows low genetic diversity in the relict Lake Bita population. Weatherfishes, however, have highly successful survival strategies. The degree of dietary overlap between the species is alarming and perhaps critical if food is found to be a limiting factor.

  6. RESULTS FROM THE U.S. DOE 2006 SAVE ENERGY NOW ASSESSMENT INITIATIVE: DOE's Partnership with U.S. Industry to Reduce Energy Consumption, Energy Costs, and Carbon Dioxide Emissions

    Energy Technology Data Exchange (ETDEWEB)

    Wright, Anthony L [ORNL; Martin, Michaela A [ORNL; Gemmer, Bob [U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy; Scheihing, Paul [U.S. Department of Energy, Industrial Technologies Program; Quinn, James [U.S. Department of Energy

    2007-09-01

    In the wake of Hurricane Katrina and other severe storms in 2005, natural gas supplies were restricted, prices rose, and industry sought ways to reduce its natural gas use and costs. In October 2005, U.S. Department of Energy (DOE) Energy Secretary Bodman launched his Easy Ways to Save Energy campaign with a promise to provide energy assessments to 200 of the largest U.S. manufacturing plants. A major thrust of the campaign was to ensure that the nation's natural gas supplies would be adequate for all Americans, especially during home heating seasons. In a presentation to the National Press Club on October 3, 2005, Secretary Bodman said: 'America's businesses, factories, and manufacturing facilities use massive amounts of energy. To help them during this period of tightening supply and rising costs, our Department is sending teams of qualified efficiency experts to 200 of the nation's most energy-intensive factories. Our Energy Saving Teams will work with on-site managers on ways to conserve energy and use it more efficiently.' DOE's Industrial Technologies Program (ITP) responded to the Secretary's campaign with its Save Energy Now initiative, featuring a new and highly cost-effective form of energy assessments. The approach for these assessments drew heavily on the existing resources of ITP's Technology Delivery component. Over the years, ITP-Technology Delivery had worked with industry partners to assemble a suite of respected software decision tools, proven assessment protocols, training curricula, certified experts, and strong partnerships for deployment. Because of the program's earlier activities and the resources that had been developed, ITP was prepared to respond swiftly and effectively to the sudden need to promote improved industrial energy efficiency. Because of anticipated supply issues in the natural gas sector, the Save Energy Now initiative strategically focused on natural gas savings and targeted the

  7. Global Environmental Change: What Can Health Care Providers and the Environmental Health Community Do About It Now?

    Science.gov (United States)

    Schwartz, Brian S.; Parker, Cindy; Glass, Thomas A.; Hu, Howard

    2006-01-01

    The debate about whether global environmental change is real is now over; in its wake is the realization that it is happening more rapidly than predicted. These changes constitute a profound challenge to human health, both as a direct threat and as a promoter of other risks. We call on health care providers to inform themselves about these issues and to become agents of change in their communities. It is our responsibility as clinicians to educate patients and their communities on the connections between regressive policies, unsustainable behaviors, global environmental changes, and threats to health and security. We call on professional organizations to assist in educating their members about these issues, in helping clinicians practice behavior change with their patients, and in adding their voices to this issue in our statehouses and Congress. We call for the development of carbon- and other environmental-labeling of consumer products so individuals can make informed choices; we also call for the rapid implementation of policies that provide tangible economic incentives for choosing environmentally sustainable products and services. We urge the environmental health community to take up the challenge of developing a global environmental health index that will incorporate human health into available “planetary health” metrics and that can be used as a policy tool to evaluate the impact of interventions and document spatial and temporal shifts in the healthfulness of local areas. Finally, we urge our political, business, public health, and academic leaders to heed these environmental warnings and quickly develop regulatory and policy solutions so that the health of populations and the integrity of their environments will be ensured for future generations. PMID:17185267

  8. Global environmental change: what can health care providers and the environmental health community do about it now?

    Science.gov (United States)

    Schwartz, Brian S; Parker, Cindy; Glass, Thomas A; Hu, Howard

    2006-12-01

    The debate about whether global environmental change is real is now over; in its wake is the realization that it is happening more rapidly than predicted. These changes constitute a profound challenge to human health, both as a direct threat and as a promoter of other risks. We call on health care providers to inform themselves about these issues and to become agents of change in their communities. It is our responsibility as clinicians to educate patients and their communities on the connections between regressive policies, unsustainable behaviors, global environmental changes, and threats to health and security. We call on professional organizations to assist in educating their members about these issues, in helping clinicians practice behavior change with their patients, and in adding their voices to this issue in our statehouses and Congress. We call for the development of carbon and other environmental-labeling of consumer products so individuals can make informed choices; we also call for the rapid implementation of policies that provide tangible economic incentives for choosing environmentally sustainable products and services. We urge the environmental health community to take up the challenge of developing a global environmental health index that will incorporate human health into available "planetary health" metrics and that can be used as a policy tool to evaluate the impact of interventions and document spatial and temporal shifts in the healthfulness of local areas. Finally, we urge our political, business, public health, and academic leaders to heed these environmental warnings and quickly develop regulatory and policy solutions so that the health of populations and the integrity of their environments will be ensured for future generations.

  9. With the advent of domestic 3-dimensional (3D) printers and their associated reduced cost, is it now time for every medical school to have their own 3D printer?

    Science.gov (United States)

    Balestrini, Christopher; Campo-Celaya, Tatiana

    2016-01-01

    Anatomy is the backbone of medical education and new techniques to improve learning are frequently explored. With the introduction of 3D printers specifically for the home market, the price of this technology has reached affordable levels. Using patient scan data, accurate 3D models can be printed that represent real human variation in anatomy to provide an innovative, inexpensive and valuable adjunct to anatomical teaching. Is it now time for every medical school to have their own 3D printer?

  10. The Unsteady Mainstay of the Family: Now Adult Children’s Retrospective View on Social Support in Relation to Their Parent’s Heart Transplantation

    Directory of Open Access Journals (Sweden)

    Susanna Ågren

    2014-01-01

    Full Text Available The needs for support among children with a seriously ill parent, who is waiting for heart transplantation, are unknown today. The aim was to describe now adult children’s experiences of social support in relation to a parent’s heart transplant during childhood. Nine females and four males were interviewed. The median age for the children was 18 at the transplantation and their parents had been ill before for 18 months (median and on waiting list for 161 days (mean. Three categories emerged: health care professionals’ approaches, family and friends’ approaches, and society approaches. Our results show that there was lack of support for children of heart transplantation patients. Support in the shape of information was in most cases provided by the sick or healthy parent. It is of great clinical importance to develop psychosocial support programs for children with a seriously ill parent waiting for heart transplantation (before, during, and after surgery.

  11. Operational wave now- and forecast in the German Bight as a basis for the assessment of wave-induced hydrodynamic loads on coastal dikes

    Science.gov (United States)

    Dreier, Norman; Fröhle, Peter

    2017-12-01

    The knowledge of the wave-induced hydrodynamic loads on coastal dikes including their temporal and spatial resolution on the dike in combination with actual water levels is of crucial importance of any risk-based early warning system. As a basis for the assessment of the wave-induced hydrodynamic loads, an operational wave now- and forecast system is set up that consists of i) available field measurements from the federal and local authorities and ii) data from numerical simulation of waves in the German Bight using the SWAN wave model. In this study, results of the hindcast of deep water wave conditions during the winter storm on 5-6 December, 2013 (German name `Xaver') are shown and compared with available measurements. Moreover field measurements of wave run-up from the local authorities at a sea dike on the German North Sea Island of Pellworm are presented and compared against calculated wave run-up using the EurOtop (2016) approach.

  12. START NOW - a comprehensive skills training programme for female adolescents with oppositional defiant and conduct disorders: study protocol for a cluster-randomised controlled trial.

    Science.gov (United States)

    Kersten, Linda; Prätzlich, Martin; Mannstadt, Sandra; Ackermann, Katharina; Kohls, Gregor; Oldenhof, Helena; Saure, Daniel; Krieger, Katrin; Herpertz-Dahlmann, Beate; Popma, Arne; Freitag, Christine M; Trestman, Robert L; Stadler, Christina

    2016-12-01

    In Europe, the number of females exhibiting oppositional defiant disorder (ODD) and conduct disorder (CD) is growing. Many of these females live in youth welfare institutions. Consequently, there is a great need for evidence-based interventions within youth welfare settings. A recently developed approach targeting the specific needs of girls with ODD and CD in residential care is START NOW. The aim of this group-based behavioural skills training programme is to specifically enhance emotional regulation capacities to enable females with CD or ODD to appropriately deal with daily-life demands. It is intended to enhance psychosocial adjustment and well-being as well as reduce oppositional and aggressive behaviour. We present the study protocol (version 4.1; 10 February 2016) of the FemNAT-CD intervention trial titled 'Group-Based Treatment of Adolescent Female Conduct Disorders: The Central Role of Emotion Regulation'. The study is a prospective, confirmatory, cluster-randomised, parallel-group, multi-centre, randomised controlled trial with 128 institutionalised female adolescents who fulfil the diagnostic criteria of ODD and/or CD. Institutions/wards will be randomised either to provide the 12-week skills training as an add-on intervention or to provide treatment as usual. Once the first cycle is completed, each institution will run a second cycle with the opposite condition. Primary endpoints are the pre-post change in number of CD/ODD symptoms as assessed by a standardised, semi-structured psychiatric interview (Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime, CD/ODD section) between baseline and the end of intervention, as well as between baseline and a 3-month follow-up point. Secondary objectives include pre-post change in CD/ODD-related outcome measures, most notably emotional regulation on a behavioural and neurobiological level after completion of START NOW compared with treatment as usual. To our

  13. Comparison of VerifyNow-P2Y12 test and Flow Cytometry for monitoring individual platelet response to clopidogrel. What is the cut-off value for identifying patients who are low responders to clopidogrel therapy?

    Directory of Open Access Journals (Sweden)

    Castelli Alfredo

    2009-05-01

    Full Text Available Abstract Background Dual anti-platelet therapy with aspirin and a thienopyridine (DAT is used to prevent stent thrombosis after percutaneous coronary intervention (PCI. Low response to clopidogrel therapy (LR occurs, but laboratory tests have a controversial role in the identification of this condition. Methods We studied LR in patients with stable angina undergoing elective PCI, all on DAT for at least 7 days, by comparing: 1 Flow cytometry (FC to measure platelet membrane expression of P-selectin (CD62P and PAC-1 binding following double stimulation with ADP and collagen type I either in the presence of prostaglandin (PG E1; 2 VerifyNow-P2Y12 test, in which results are reported as absolute P2Y12-Reaction-Units (PRU or % of inhibition (% inhibition. Results Thirty controls and 52 patients were analyzed. The median percentage of platelets exhibiting CD62P expression and PAC-1 binding by FC evaluation after stimulation in the presence of PG E1 was 25.4% (IQR: 21.4–33.1% and 3.5% (1.7–9.4%, respectively. Only 6 patients receiving DAT (11.5% had both values above the 1st quartile of controls, and were defined as LR. Evaluation of the same patients with the VerifyNow-P2Y12 test revealed that the area under the receiver-operating-characteristic (ROC curve was 0.94 (95% CI: 0.84–0.98, p 213 PRU gave the maximum accuracy for the detection of patients defined as having LR by FC. Conclusion In conclusion our findings show that a cut-off value of ≤ 15% inhibition or > 213 PRU in the VerifyNow-P2Y12 test may provide the best accuracy for the identification of patients with LR.

  14. Statin intolerance: Now a solved problem

    Directory of Open Access Journals (Sweden)

    P Sikka

    2011-01-01

    Full Text Available Statins are the most effective and widely used drugs for treating dyslipidemia, a major risk factor for coronary heart disease. These are one of the safest hypolipidemic drugs but many patients are bound to discontinue statins due to their side effects. Hepatotoxicity, myotoxicity and peripheral neuropathy are important out of them. Discontinuation of statins leads to dylipidemia and its grave consequences. Hence, there should be enough strategies for statin intolerant patients, so that they can be saved from these consequences. These side effects can be avoided by the awareness of certain factors viz. potential drug interactions and dose adjustment according to patho-physiology of the patient. Baseline investigations for liver function and muscle toxicity should be done before initiating statin therapy. Here, we are discussing various options for statin intolerant hyperlipidemic patients such as lower and intermittent dosing of statins, alternate hypolipidemic drugs, red yeast rice, supplementation with coenzyme Q10 and vitamin D. A number of hypolipidemic drugs are in trial phases and hold promise for statin intolerant patients.

  15. The future of solar is now

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    For nearly half a century, the photovoltaic cell, generating DC power solely from the sun, has represented one avenue to independence of the electric power grid. Developments in renew able energy systems have finally made it easier to live with the limitations of solar power while maintaining quality of life. This article presents an overview of advances in solar power. Topics include advances in photovoltaic technology and other power sources; technology improvements in sun trackers; battery technology; unanswered questions; and energy conservation

  16. Microbial Ecology: Where are we now?

    Science.gov (United States)

    Boughner, Lisa A; Singh, Pallavi

    2016-11-01

    Conventional microbiological methods have been readily taken over by newer molecular techniques due to the ease of use, reproducibility, sensitivity and speed of working with nucleic acids. These tools allow high throughput analysis of complex and diverse microbial communities, such as those in soil, freshwater, saltwater, or the microbiota living in collaboration with a host organism (plant, mouse, human, etc). For instance, these methods have been robustly used for characterizing the plant (rhizosphere), animal and human microbiome specifically the complex intestinal microbiota. The human body has been referred to as the Superorganism since microbial genes are more numerous than the number of human genes and are essential to the health of the host. In this review we provide an overview of the Next Generation tools currently available to study microbial ecology, along with their limitations and advantages.

  17. Water in Athens Then and Now

    Science.gov (United States)

    Christaki, Maria

    2015-04-01

    The presentation examines the water sources and the water supply projects in Athens in relation to the historical, urban and demographic development since 3500 BC. Athens and the Athens basin were inhabited from the Late Neolithic period (about 5300-4500 BC.). In recent years, after thorough investigations and excavations in the north and south side of the Acropolis, the Agora and the Dipylon, conclusions were drawn regarding the historical construction and residential development of Athens. The findings show that the Athenians had settled permanently on the sides of the Acropolis from Hysteroneolithic or Final Neolithic period (3500-3000 BC.). The water provision was primarily secured by using wells and natural springs, such as the Neolithic wells near the Klepsydra spring. The climate in Attica is dry Mediterranean with sunny and dry summers and wet and mild winters. The annual precipitation in the city of Athens is about 400 mm and long dry periods are been detected in historical times all the way to today. Since prehistoric times, the city of Athens and the wider region of Attica did not contain many natural water sources so aquatic reserves were never adequate to meet the needs of residents, as these changed over time The lack of water in Attica drove its inhabitants to study the flow of rivers and penetration of rain into the earth to discover and extract hidden waters. This enabled Athenians to acquire technical expertise and develop a significant hydrotechnologic culture, as evidenced by their works. As the population of Athens and the need for water increased residents - among others - turned to obtaining water from distant sources and construct aqueducts that brought water into the city using gravity. In the mid of 6th century BC (tyranny of Peisistrateidon) and while the population was 300,000 the Peisistrateio aqueduct built. After the 6th. century BC there were, fountains, cisterns, reservoirs and aqueducts throughout the city. In Roman Athens, the requirement for large volumes of water brought about the construction of the brilliant Hadrian's aqueduct in 140. AD that supplied water to Athens for 1800 years. The large population explosion in 1922, (as Athens welcomed refugees) and the increased population of 800,000 by 1928, led to the construction of the dam of Marathon. The population of Athens in the decade 1950-1960 was 1,850,000 and opened a new water supply project, the lake Hylike. In 1981 the population of the capital region exceeded 3,000,000 and a new dam was constructed along the Mornos river. In 2001 the diversion of the Evinos river into Mornos was completed.

  18. Food Allergy: What We Know Now.

    Science.gov (United States)

    Moore, Lindsey E; Stewart, Patricia H; deShazo, Richard D

    2017-04-01

    Food allergy is an adverse immune reaction that occurs reproducibly on exposure to a given food. Prevalence rates of food allergy continue to increase worldwide, sparking continual research efforts in finding a suitable and safe cure. Food avoidance, the current standard of care, can be difficult to achieve. This review aims to provide a broad overview of immunoglobulin E-mediated food allergy, highlighting its epidemiology, masqueraders, immunopathophysiology, clinical presentation, diagnostic work-up and available preventative and treatment strategies. This review also discusses novel, investigative therapies that offer promising therapeutic options, yet require continued research efforts to determine safety effects. Inducing tolerance, whether by immunotherapy or by the administration of monoclonal antibodies, allows us to move toward a cure for food allergy, which could vastly change this field of allergic diseases in the coming decades. Copyright © 2017 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

  19. Genetics of Phenylketonuria: Then and Now.

    Science.gov (United States)

    Blau, Nenad

    2016-06-01

    More than 950 phenylalanine hydroxylase (PAH) gene variants have been identified in people with phenylketonuria (PKU). These vary in their consequences for the residual level of PAH activity, from having little or no effect to abolishing PAH activity completely. Advances in genotyping technology and the availability of locus-specific and genotype databases have greatly expanded our understanding of the correlations between individual gene variant, residual PAH activity, tetrahydrobiopterin (BH4 ) responsiveness, and the clinical PKU phenotype. Most patients (∼76%) have compound heterozygous PAH gene variants and one mutated allele may markedly influence the activity of the second mutated allele, which in turn may influence either positively or negatively the activity of the biologically active heterotetrameric form of the PAH. While it is possible to predict the level of BH4 responsiveness (∼71%) and PKU severity (∼78%) from the nature of the underlying gene variants, these relationships remain complex and incompletely understood. A greater understanding of these relationships may increase the potential for individualized management of PKU in future. Inherited deficiencies in BH4 metabolism account for about 1%-2% of all hyperphenylalaninemias and are clinically more severe than PKU. Almost 90% of all patients are deficient in 6-pyruvoyl-tetrahydropterin synthase and dihydropteridine reductase. © 2016 WILEY PERIODICALS, INC.

  20. Tooth whitening: what we now know.

    Science.gov (United States)

    Carey, Clifton M

    2014-06-01

    Current research about tooth whitening shows that it is safe and effective when manufacturer's protocol is followed, yet there are risks of which the profession and users should be aware. This update provides a summary of current research and assessment of the safety and efficacy of tooth whitening regimens. Tooth whitening has become one of the most frequently requested dental procedures by the public. The public has come to demand whiter, more perfect smiles and in response many choices for tooth whitening have been made available. These include home-based products such as toothpastes, gels, and films, as well as in-office based systems where products containing highly concentrated bleaching agents are applied under professional supervision. The profession and public have been aware of certain risks related to tooth whitening such as increased tooth sensitivity and gingival irritation. New research has shown that there are other risks such as tooth surface roughening and softening, increased potential for demineralization, degradation of dental restorations, and unacceptable color change of dental restorations. The new research is also focused on optimizing whitening procedures to reduce tooth sensitivity and to increase the persistence of the whitening. Current reports in the literature are reviewed that are related to the use of peroxide based whitening methods. These reports include in vitro studies for method optimization and mechanism as well as clinical studies on effects of various whitening regimens. When manufacturer's instructions are followed, hydrogen peroxide and carbamide peroxide based tooth whitening is safe and effective. Patients should be informed of the risks associated with tooth whitening and instructed on identification of adverse occurrences so that they may seek professional help as needed. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Understanding statements now a virtual cinch.

    Science.gov (United States)

    Weber, Danielle B; Talaga, John

    2005-04-01

    With a click of the mouse, some patients are accessing and paying their hospital bills online. Novant Health revamped its patient billing process so it's easier to understand and use. Developing a clear, concise billing statement and then implementing an online bill presentment and payment system resulted in improved customer relations, fewer payment processing errors, and faster receipt of payment.

  2. Few-body physics: Then and now

    International Nuclear Information System (INIS)

    Friar, J.L.

    1994-01-01

    This review describes past progress in selected topics of few-body nuclear physics, as well as calculations and experiments that the author believes necessary for further orderly progress. Review also gives specific data on binding energies and nuclear radii. 36 references

  3. NOAA History - NOAA Then and Now

    Science.gov (United States)

    NOAA History Banner gold bar divider home - takes you to index page about the site contacts noaa formed agency. The documents in this section include information on the history of the formation of NOAA . agency history noaa seal NOAA Historical background information on NOAA as an agency of the Department of

  4. The sustainable development: now or never

    International Nuclear Information System (INIS)

    Bourg, D.; Rayssac, G.L.

    2006-11-01

    The fossil energies sources run out, the climatic change, the pollution, the ecosystems destruction and the world inequalities are threats which hang on the humanity. What must we do? After a presentation of the earth situation, the authors detail some propositions. The solutions need a new ethic, public policies and involvements of each of us. (A.L.B.)

  5. Main Maralinga test sites now clean

    International Nuclear Information System (INIS)

    Anon

    2000-01-01

    Landscaping and revegetating work will soon he complete, bringing the Maralinga Rehabilitation Project to a conclusion on time and within its 108 million budget. The project involved removing surface soil from the resulting plutonium-contaminated areas and the treatment of a number of contaminated debris pits.The Australian Radiation Protection and Nuclear Safety Agency (ARPANSA) monitored the clean-up operation to ensure that the clearance criteria has been met. ARPANSA has indicated that the burial trenches have been constructed consistent with the national Code of Practice for the Near-Surface Disposal of Radioactive Waste

  6. A Healthy Start Can Begin Now

    Science.gov (United States)

    A healthy pregnancy begins before you ever become pregnant. Give yourself the best chance for a healthy pregnancy and healthy baby before you start down the road to motherhood. If you smoke, now’s a great time to quit.

  7. The European energy community is now

    International Nuclear Information System (INIS)

    Andoura, Sami; Buzek, Jerzy; Delors, Jacques; Vitorino, Antonio

    2013-01-01

    On the eve of the European Council on 22 May dealing with energy issues, the Jacques Delors Institute publishes a Tribune calling for the implementation of a positive agenda for the European energy policy and the definition of the concrete bases of a genuine European Energy

  8. Laser acceleration... now with added fibre

    CERN Multimedia

    Katarina Anthony

    2012-01-01

    Laser acceleration technology is plagued by two main issues: efficiency and repetition rates. In other words, lasers consume too much power and cannot sustain accelerating particles long enough to produce collisions. ICAN, a new EU-funded project, is examining how fibre lasers may help physicists tackle these issues.   A diode-pumped fibre laser. (Image courtesy of Laser Zentrum Hannover.) The International Coherent Amplification Network (ICAN) is studying the potential of lasers for collision physics. CERN is a beneficiary of the project and will collaborate with 15 other institutes from around the world, including KEK in Japan, Fermilab in the USA, and DESY in Germany. “The network is looking into existing fibre laser technology, which we believe has fantastic potential for accelerators,” says Gerard Mourou, ICAN co-ordinator at the École Polytechnique in France. “The hope is to make laser acceleration competitive with traditional radio-fre...

  9. Software Training Classes Now Open | Poster

    Science.gov (United States)

    By Nancy Parrish, Staff Writer                                            Data Management Services, Inc. (DMS), has announced the opening of its spring session of software training classes, available to all employees at NCI at Frederick. Classes begin on March 31 and run through June 30.

  10. Candu technology: the next generation now

    International Nuclear Information System (INIS)

    Hopwood, J.M.; Duffey, R.B.; Torgerson, D.F.

    2001-01-01

    We describe the development philosophy, direction and concepts that are being utilized by AECL to refine the CANDU reactor to meet the needs of current and future competitive energy markets. The technology development path for CANDU reactors is based on the optimization of the pressure tube concept. Because of the inherent modularity and flexibility of this basis for the core design, it is possible to provide a seamless and continuous evolution of the reactor design and performance. There is no need for a drastic shift in concept, in technology or in fuel. By continual refinement of the flow and materials conditions in the channels, the basic reactor can be thermally and operationally efficient, highly competitive and economic, and highly flexible in application. Thus, the design can build on the successful construction and operating experience of the existing plants, and no step changes in development direction are needed. This approach minimizes investor, operator and development risk but still provides technological, safety and performance advances. In today's world energy markets, major drivers for the technology development are: (a) reduced capital cost; (b) improved operation; (c) enhanced safety; and (d) fuel cycle flexibility. The drivers provide specific numerical targets. Meeting these drivers ensures that the concept meets and exceeds the customer economic, performance, safety and resource use goals and requirements, including the suitable national and international standards. This logical development of the CANDU concept leads naturally to the 'Next Generation' of CANDU reactors. The major features under development include an optimized lattice for SEU (slightly enriched uranium) fuel, light water cooling coupled with heavy water moderation, advanced fuel channels and CANFLEX fuel, optimization of plant performance, enhanced thermal and BOP (balance of plant) efficiency, and the adoption of layout and construction technology adapted from successful on-time plant construction projects. The development program is discussed and shown to meet the technology needs and targets. (authors)

  11. The VESUVIO Spectrometer Now and When?

    International Nuclear Information System (INIS)

    Seel, A G; Krzystyniak, M; Fernandez-Alonso, F

    2014-01-01

    The current layout and mechanics of the VESUVIO spectrometer are presented in light of spectroscopic measurements using electron-volt neutrons. A brief background to the theoretical framework of deep inelastic neutron scattering is presented, with focus on data collection and instrumental design. The current capabilities and research themes for VESUVIO are discussed, and possible future instrumental developments highlighted which will enhance the instrument's ability to meet scientific inquiry and expectation

  12. The VESUVIO Spectrometer Now and When?

    Science.gov (United States)

    Seel, A. G.; Krzystyniak, M.; Fernandez-Alonso, F.

    2014-12-01

    The current layout and mechanics of the VESUVIO spectrometer are presented in light of spectroscopic measurements using electron-volt neutrons. A brief background to the theoretical framework of deep inelastic neutron scattering is presented, with focus on data collection and instrumental design. The current capabilities and research themes for VESUVIO are discussed, and possible future instrumental developments highlighted which will enhance the instrument's ability to meet scientific inquiry and expectation.

  13. What now, Asclepius? Lessons from Olympus.

    Science.gov (United States)

    Moore, M R

    1996-10-01

    Asclepius, the Greek and Roman god of healing, is called before a council of gods on Mount Olympus to account for the shortcomings of his mortal descendants, the present day physicians. Accusations by the gods and Asclepius' defense and explanation bring the gods an understanding of human history and what physicians must become if humanity is to triumph over disease. Asclepius hopes the modern medical profession will understand also.

  14. The Trouble with Doctoral Aspiration Now

    Science.gov (United States)

    Burford, James

    2018-01-01

    This article attends to the affective-political dimensions of doctoral aspiration. It considers why doctoral students continue to hope for an 'academic good life' in spite of the depressed and precarious features of the academic present. The article emerges from 2013 research with ten doctoral students in the Arts and Social Sciences, at a…

  15. The here and now ... or then?

    CERN Multimedia

    2008-01-01

    Is the universe - correction, 'our' universe - no more than a speck of cosmic dust amid an infinite number of parallel worlds? A staple of mind-bending science fiction, the possibility of multiple universes has long intrigued hard-nosed physicists, mathematicians and cosmologists.

  16. Energy for Tomorrow's World - Acting Now

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-06-01

    WEC, with over 75 years of history, is concentrating on study and research about production and utilization of sustainable energy and regional and technology program for the maximum benefit of human beings. WEC is a global multi energy organization with supports from private companies, public corporations, governments, academics and famous people in around one hundred countries. The activities of WEC include major energy production and consumption market. 18 figs., 17 tabs.

  17. Rural Math Talent, Now and Then

    Science.gov (United States)

    Howley, Craig B.; Showalter, Daniel; Klein, Robert; Sturgill, Derek J.; Smith, Michael A.

    2013-01-01

    This article interprets inequality evident at the intersection of three realms: (a) mathematical talent (as a cultural phenomenon); (b) rural place and rural life; and (c) future economic, political, and ecological developments. The discussion explains this outlook on inequality, contextualizes interest in rural mathematics education, presents the…

  18. Guess what I am doing now!

    Indian Academy of Sciences (India)

    Lawrence

    mathematics and English. ... wanted to do when I grew up, I used to have a hard time choosing between ... people by pausing to think about whether I wanted to study fur- ... started reading up about his life and his work, I became fascinated.

  19. Long-baseline experiments, now and soon!

    Indian Academy of Sciences (India)

    2012-11-01

    Nov 1, 2012 ... Technologically, the big step for mankind is the proof of the liquid ... OPERA has analysed double their data but is yet to find more tau .... The best-fit values of sin2 2θ13 range between 0.04 and 0.11, but more con- .... if sterile neutrinos, which would not interact via the Z boson exchange, were being pro-.

  20. Now & Then: Roger Whitmore, Police Officer.

    Science.gov (United States)

    Barnes, Sue; Michalowicz, Karen Dee

    1995-01-01

    Discusses police officers' use of mathematics when reconstructing an accident scene; and the history of algebra, including al-Khwarizmi's works on the theory of equations, the Rhind Papyrus, a Chinese and an Indian manuscript on systems of linear and quadratic equations, and Diophantus'"syncopated algebra." (10 references) (EK)

  1. Shaping-lathe headrig now commercially available

    Science.gov (United States)

    P. Koch

    1975-01-01

    On September 12, 1975, twenty-five sawmillers from throughout North America watched as a new headrig produced cants of various shapes and a usable residue of flakes from logs of irregular contour. The demonstration at the Stetson-Ross plant in Seattle, Washington, was the unveiling of the commercial model of a design introduced by the Southern Forest Experiment Station...

  2. [Claude Bernard - then and now].

    Science.gov (United States)

    Wise, Peter

    2017-01-01

    The early life of Claude Bernard - dreamer and frustrated playwright - reveals no indication of his future scientific aptitude. Cartesian doubt, a principle that he would adhere to lifelong, clouded a failed pharmacy apprenticeship that led to medical studies in Paris - but without great success. Research was his only aim, it was made possible only by a lucrative but unsuccessful arranged marriage. His passion for work and over-riding principles of truth and proof would ultimately allow him to stand out from his peers with recognition by multiple French professional societies - and the wider scientific world. In today's world, the two centuries-long practice of homeopathy illustrates his abhorrence of ''practice without proof'': a dominance by economic factors that is apparent in cancer chemotherapy, where new drug approval is often based on statistics rather than genuine clinical benefit. Bernard was indeed sceptical about the (ab)use of statistics - a caution even more necessary today. His experimental method stands out as a signal principle in research. This was cleverly taken out of context by Emile Zola, who used it to support his ideas on the literary naturalism that appeared in his Rougon-Macquart cycle of books - and that led him to dedicate his book, Le Roman Expérimental, to Claude Bernard himself. © Société de Biologie, 2017.

  3. Carbohydrate Chemistry from Fischer to Now

    Indian Academy of Sciences (India)

    In this brief article, this intriguing field of natural products chemistry is ... six carbon atoms, five hydroxyl groups (one primary and the other ..... to elucidate the mechanism of ..... As a postscript, a quotation from the review by P H Seeberger and.

  4. Energy for tomorrow's world. Acting now

    International Nuclear Information System (INIS)

    2000-01-01

    The statement 2000 of WEC (World Energy Council) is an extremely important document, committed to overcoming the energy shortage where it is found, pointing out, from one hand, the importance of quality and safety in the energy supply, and, from the other hand, the necessity of minimizing the impact of energy development on the environment and mankind health [it

  5. Doing it now, later, or never

    NARCIS (Netherlands)

    Cingiz, K.; Flesch, J.; Herings, P.J.J.; Predtetchinski, A.

    2015-01-01

    We study centipede games played by an infinite sequence of players. Following the literature on time-inconsistent preferences, we distinguish two types of decision makers, naive and sophisticated, and the corresponding solution concepts, naïve ϵ-equilibrium and sophisticated ϵ-equilibrium. We show

  6. East coast development overview : why now?

    International Nuclear Information System (INIS)

    Anderson, J.

    1998-01-01

    Progress achieved in developing East coast natural gas markets was discussed. Mobil, Shell, Imperial, Mosbacher and Nova Scotia Resources received the go-ahead for the Sable Offshore Energy Project last December. The owner companies created Sable Offshore Energy Inc. (SOE Inc.) for managing and operating the development. Mobil (which has 50 per cent of the total invested in the Sable offshore project) and their partners will spend an average of one million dollars per day in Nova Scotia over the next 22 months in order to ensure that they will deliver gas from the offshore site by late 1999. That is in addition to the 400 million dollars already spent by the consortium in the province of Nova Scotia. Job creation, of particular significance in the Atlantic provinces, is also expected to be a significant factor in lifting the GDP of Nova Scotia to three per cent in 1998. According to an estimate by the Bank of Nova Scotia, the Sable and pipeline projects alone will create more than 7,500 spin-off jobs. The five major factors which make eastern Canada development possible and economically attractive are: (1) resource potential, (2) technological advancements, (3) alliances, (4) market proximity, and (5) the rapidly expanding global market for natural gas. Each of these factors and how they impact on the East coast natural gas industry were discussed in some detail

  7. Preventing surgical site infection. Where now?

    LENUS (Irish Health Repository)

    Humphreys, H

    2009-12-01

    Surgical site infection (SSI) is increasingly recognised as a measure of the quality of patient care by surgeons, infection control practitioners, health planners and the public. There is increasing pressure to compare SSI rates between surgeons, institutions and countries. For this to be meaningful, data must be standardised and must include post-discharge surveillance (PDS) as many superficial SSIs do not present to the original institution. Further work is required to determine the best method of conducting PDS. In 2008 two important documents on SSI were published from the Society for Healthcare Epidemiology of America\\/The Infectious Disease Society of America and the National Institute for Health and Clincal Excellence, UK. Both emphasise key aspects during the preoperative, operative and postoperative phases of patient care. In addition to effective interventions known to be important for some time, e.g. not shaving the surgical site until the day of the procedure, there is increasing emphasis on physiological parameters, e.g. blood glucose concentrations, oxygen tensions and body temperature. Laparoscopic procedures are increasingly associated with reduced SSI rates, and the screening and decontamination of meticillin-resistant Staphylococcus aureus carriers is effective for certain surgical procedures but has to be balanced by cost and the risk of mupirocin resistance. Finally, there is a need to convert theory into practice by the rigorous application of SSI healthcare bundles. Recent studies suggest that, with a multidisciplinary approach, simple measures can be effective in reducing SSI rates.

  8. 'Now she has become my daughter'

    DEFF Research Database (Denmark)

    Maastrup, Ragnhild; Weis, Janne; Engsig, Anne B

    2018-01-01

    BACKGROUND: Based on the Family-Centred Care philosophy, skin-to-skin contact is a key activity in neonatal care, and use of this practice is increasing also with extremely preterm infants. Little is known about parents' immediate experiences of and readiness for skin-to-skin contact, while...... their fragile infant may still not be 'on safe ground'. Knowledge about parents' experiences might reduce doubt and reluctance among healthcare professionals to use skin-to-skin contact with extremely preterm infants and thus increase its dissemination in practice. AIMS AND OBJECTIVES: To explore parents...... developed an overall confidence in the value of bonding, independent of the infant's survival. CONCLUSIONS: Parents progressed from ambivalence to a feeling of fundamental mutual needs for skin-to-skin contact. Parents found the bonding facilitated by skin-to-skin contact to be valuable, regardless...

  9. The flipped classroom: now or never?

    Science.gov (United States)

    Hawks, Sharon J

    2014-08-01

    Pedagogical changes and new models of delivering educational content should be considered in the effort to address the recommendations of the 2007 Institute of Medicine report and Benner's recommendations on the radical transformation of nursing. Transition to the nurse anesthesia practice doctorate addresses the importance of these recommendations, but educational models and specific strategies on how to implement changes in educational models and systems are still emerging. The flipped classroom (FC) is generating a considerable amount of buzz in academic circles. The FC is a pedagogical model that employs asynchronous video lectures, reading assignments, practice problems, and other digital, technology-based resources outside the classroom, and interactive, group-based, problem-solving activities in the classroom. This FC represents a unique combination of constructivist ideology and behaviorist principles, which can be used to address the gap between didactic education and clinical practice performance. This article reviews recent evidence supporting use of the FC in health profession education and suggests ways to implement the FC in nurse anesthesia educational programs.

  10. Bridging Inequality from Both Sides Now

    Science.gov (United States)

    Fiske, Susan T.; Molm, Linda D.

    2010-01-01

    Because inequality is one of the central concerns of sociologists, it has been addressed, in various ways, by virtually all of the major traditions of sociological social psychology--social structure and personality, symbolic interactionism, and group processes. For those who work in the social structure and personality tradition, inequality…

  11. Training + Technology: The Future Is Now.

    Science.gov (United States)

    Heathman, Dena J.; Kleiner, Brian H.

    1991-01-01

    New applications of computer-assisted training being developed include telecommunications, artificial intelligence, soft skills training, and performance support systems. Barriers to acceptance are development time, costs, and lack of human contact. (SK)

  12. Closing the Gender Gap: Act Now

    Science.gov (United States)

    OECD Publishing (NJ3), 2012

    2012-01-01

    Gender gaps are pervasive in all walks of economic life and imply large losses in terms of foregone productivity and living standards to the individuals concerned and the economy. This new OECD report focuses on how best to close these gender gaps under four broad headings: (1) Gender equality, social norms and public policies; and gender equality…

  13. Clean Cities Now Vol. 16.1

    Energy Technology Data Exchange (ETDEWEB)

    None

    2012-05-01

    Biannual newsletter for the U.S. Department of Energy's Clean Cities initiative. The newsletter includes feature stories on advanced vehicle deployment, idle reduction, and articles on Clean Cities coalition successes across the country.

  14. Hydrogen: What's Different Now

    Energy Technology Data Exchange (ETDEWEB)

    Gearhart, Chris C [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2018-02-27

    This is an exciting time for hydrogen fuel-cell electric vehicles (FCEVs). They seem to be on the verge of a major market breakthrough. However, those of us who have been working in the hydrogen and FC industry for a while are familiar with the boom and bust cycle of FCEV hype-it feels like we have been here before. The first FC automobile was designed as far back as the 1960s. NASA was using FCs to power its spacecraft, and, in 1966, General Motors (GM) used this space-age technology in the prototype GM Electrovan. The Electrovan used the body and chassis of GM's Handivan, their production utility van at the time. The FC and hydrogen components for this vehicle filled nearly the entire available space of the van. At this point, FCs were clearly too expensive and impractical for production vehicles.

  15. Hospital marketing: now more than ever.

    Science.gov (United States)

    Cameron, A N

    1984-01-01

    To achieve success in any significant marketing endeavor, four basic ingredients are needed. 1. A product or service that the customer needs and wants. 2. A marketing organization capable of bringing the product or service in contact with the customer. 3. A marketing plan, endorsed by top management, which identifies ways to achieve desired goals. 4. Constant vigilance in the marketplace to determine the effectiveness of the marketing effort and course corrections needed in the future. The health care industry is overcoming many of its misconceptions about marketing, but there is a long way to go. In the end, the hospitals that provide good quality care, based on the needs of the patients, and that build relationships before the need arises, will be successful. These will be the hospitals that do real marketing.

  16. Now's the Time: Implementing Performance Management

    Science.gov (United States)

    Legutko, Lee V.

    2012-01-01

    During the past several years, school systems have implemented a variety of organizational improvement initiatives, such as Six Sigma, Balanced Scorecards, Baldrige Criteria, activity-based costing, and managing for results. Unfortunately, evidence of sustained success is fleeting as school districts remain trapped in a time warp of command,…

  17. A novel insulin resistance index to monitor changes in insulin sensitivity and glucose tolerance: the ACT NOW study.

    Science.gov (United States)

    Tripathy, Devjit; Cobb, Jeff E; Gall, Walter; Adam, Klaus-Peter; George, Tabitha; Schwenke, Dawn C; Banerji, MaryAnn; Bray, George A; Buchanan, Thomas A; Clement, Stephen C; Henry, Robert R; Kitabchi, Abbas E; Mudaliar, Sunder; Ratner, Robert E; Stentz, Frankie B; Reaven, Peter D; Musi, Nicolas; Ferrannini, Ele; DeFronzo, Ralph A

    2015-05-01

    The objective was to test the clinical utility of Quantose M(Q) to monitor changes in insulin sensitivity after pioglitazone therapy in prediabetic subjects. Quantose M(Q) is derived from fasting measurements of insulin, α-hydroxybutyrate, linoleoyl-glycerophosphocholine, and oleate, three nonglucose metabolites shown to correlate with insulin-stimulated glucose disposal. Participants were 428 of the total of 602 ACT NOW impaired glucose tolerance (IGT) subjects randomized to pioglitazone (45 mg/d) or placebo and followed for 2.4 years. At baseline and study end, fasting plasma metabolites required for determination of Quantose, glycated hemoglobin, and oral glucose tolerance test with frequent plasma insulin and glucose measurements to calculate the Matsuda index of insulin sensitivity were obtained. Pioglitazone treatment lowered IGT conversion to diabetes (hazard ratio = 0.25; 95% confidence interval = 0.13-0.50; P < .0001). Although glycated hemoglobin did not track with insulin sensitivity, Quantose M(Q) increased in pioglitazone-treated subjects (by 1.45 [3.45] mg·min(-1)·kgwbm(-1)) (median [interquartile range]) (P < .001 vs placebo), as did the Matsuda index (by 3.05 [4.77] units; P < .0001). Quantose M(Q) correlated with the Matsuda index at baseline and change in the Matsuda index from baseline (rho, 0.85 and 0.79, respectively; P < .0001) and was progressively higher across closeout glucose tolerance status (diabetes, IGT, normal glucose tolerance). In logistic models including only anthropometric and fasting measurements, Quantose M(Q) outperformed both Matsuda and fasting insulin in predicting incident diabetes. In IGT subjects, Quantose M(Q) parallels changes in insulin sensitivity and glucose tolerance with pioglitazone therapy. Due to its strong correlation with improved insulin sensitivity and its ease of use, Quantose M(Q) may serve as a useful clinical test to identify and monitor therapy in insulin-resistant patients.

  18. Achieving a milestone: AMOR is now archived in Portico and indexed in CAS

    Directory of Open Access Journals (Sweden)

    R.N Sugitha Nadarajah

    2016-10-01

    Full Text Available The journal of Advances in Modern Oncology Research (AMOR is proud to announce its partnership with Portico, a leading digital preservation service provider, to ensure the long term accessibility of its published contents. In addition, it is now indexed by the gold standard of chemical information database Chemical Abstracts Services (CAS after publishing only six bimonthly issues, dating back to October 2015. AMOR’s Editor-in-Chief Dr. Omar Abdel-Rahman proudly shares: “Our vision is to be far more than just a journal, we want to be a platform that publishes high quality cancer research contents from all over the world. I think we are progressing, at an acceptable pace, in that direction."The Portico archive is a “centralized repository of tens of thousands of e-journals, e-books, and other electronic content, replicated to ensure security,” according to the registry organization. “Content comes into the archive under formal preservation agreements with publishers. Content providers submit source files to Portico, and we repackage these source files into an archival format and provide long-term archival management and format migration as needed. Our approach is driven by our commitment to meeting clear preservation goals,” it states. AMOR’s Managing Editor Dr. TS Jong, when asked to comment about the impact of this development, adds: “AMOR is committed towards meeting the highest international publication standards and as such, has a clear archiving and indexing roadmap to sustain our growth. The journal acknowledges the importance of ensuring the continuous accessibility of our published articles in multiple repositories. Therefore, we are delighted with the recent partnership between AMOR and Portico, a well-known third-party repository service provider, to safeguard the long-term availability of our contents.”Archiving AMOR’s articles within Portico ensures that the materials published are always available for access. In

  19. Tracing the Milky Way spiral arms. Now and in the Gaia era : Now and in the Gaia era

    NARCIS (Netherlands)

    Monguio, M.; Grosbo, P.; Figueras, F.; Antoja Castelltort, Teresa; Torra, J.; Zapatero Osorio, M.R.; Gorgas, J.; Maíz Apellániz, J.; Pardo, J.R.; Gil de Paz, A.

    Whereas it is well established that spiral arms are important agents driving the evolution of the galactic disks, the observational evidences of the outer spiral arms in our Milky Way are frustratingly inconclusive. In order to shed some light on the still remaining open questions, we are developing

  20. Tracing the Milky Way spiral arms. Now and in the Gaia era : Now and in the Gaia era

    NARCIS (Netherlands)

    Monguio, M.; Grosbo, P.; Figueras, F.; Antoja Castelltort, Teresa; Torra, J.; Zapatero Osorio, M.R.; Gorgas, J.; Maíz Apellániz, J.; Pardo, J.R.; Gil de Paz, A.

    2011-01-01

    Whereas it is well established that spiral arms are important agents driving the evolution of the galactic disks, the observational evidences of the outer spiral arms in our Milky Way are frustratingly inconclusive. In order to shed some light on the still remaining open questions, we are developing

  1. Bird Species and Climate Change. The Global Status Report. A synthesis of current scientific understanding of anthropogenic climate change impacts on global bird species now, and projected future effects

    International Nuclear Information System (INIS)

    Wormworth, J.; Mallon, K.

    2006-01-01

    The results of a global analysis of current and future impacts of climate change on birds are presented. The report reviews more than 200 research reports to assemble a clear and consistent picture of climatic risk to this important animal group, illustrated with numerous examples and case studies. It is found that: climate change now affects bird species' behaviour, ranges and population dynamics; some bird species are already experiencing strong negative impacts from climate change; and in future, subject to greenhouse gas emissions levels and climatic response, climate change will put large numbers of bird species at risk of extinction, with estimates of extinction rates varying from 2 to 72%, depending on the region, climate scenario and potential for birds to shift to new habitat

  2. Bird Species and Climate Change. The Global Status Report. A synthesis of current scientific understanding of anthropogenic climate change impacts on global bird species now, and projected future effects

    Energy Technology Data Exchange (ETDEWEB)

    Wormworth, J.; Mallon, K. [Climate Risk Pty Limited, Fairlight (Australia)

    2006-07-01

    The results of a global analysis of current and future impacts of climate change on birds are presented. The report reviews more than 200 research reports to assemble a clear and consistent picture of climatic risk to this important animal group, illustrated with numerous examples and case studies. It is found that: climate change now affects bird species' behaviour, ranges and population dynamics; some bird species are already experiencing strong negative impacts from climate change; and in future, subject to greenhouse gas emissions levels and climatic response, climate change will put large numbers of bird species at risk of extinction, with estimates of extinction rates varying from 2 to 72%, depending on the region, climate scenario and potential for birds to shift to new habitat.

  3. We Insist! Freedom Now Suite: O Ativismo Político de Max Roach no Movimento de Direitos Civis através do Jazz (Estados Unidos, 1950-1960

    Directory of Open Access Journals (Sweden)

    Edimar Luciano Silva

    2013-12-01

    Full Text Available Ao longo de sua história o jazz projetou-se como uma voz dos afroamericanos e, nos Estados Unidos, a partir do final dos anos 1950, a relação entre este gênero musical e a política se intensificou. O presente estudo elegeu o jazz como objeto e estabeleceu como recorte temporal o período que abrange de final os anos 1950 e 1960, momento de grande efervescência dos movimentos pelos direitos civis nos Estados Unidos, com destaque para a figura do baterista Max Roach e uma de suas obras: We Insist Freedom Now Suite. A partir desta escolha pretendemos compreender a atuação de Max Roach como ativista político e a forma como ele lançou mão da música para inserir-se no movimento dos direitos civis.

  4. Look What Microcomputers Are Up to Now!

    Science.gov (United States)

    Wilkins, Mary E.

    1989-01-01

    A teacher of hearing-impaired students describes commercially available software for teaching sign language and finger spelling, lists sources of information about other software programs, and offers suggestions to encourage teachers to utilize computers in their classrooms. (JDD)

  5. New caribou crisis – then and now

    Directory of Open Access Journals (Sweden)

    Robert A. Ruttan

    2012-03-01

    Full Text Available The reported decline of the Bathurst herd has caused considerable concern and has raised rumours of a “crisis” in which there is a possibility of extinction. This paper reflects on relevant lessons learned from the officially declared “crisis” of population decline in 1955/56 and a second crisis of overpopulation identified by the author a decade later.

  6. Modernising medical regulation: where are we now?

    Science.gov (United States)

    Waring, Justin; Dixon-Woods, Mary; Yeung, Karen

    2010-01-01

    This paper aims to outline and comment on the changes to medical regulation in the UK that provide the background to a special issue of the Journal of Health Organization and Management on regulating doctors. This paper takes the form of a review. Although the UK medical profession enjoyed a remarkably stable regulatory structure for most of the first 150 years of its existence, it has undergone a striking transformation in the last decade. Its regulatory form has mutated from one of state-sanctioned collegial self-regulation to one of state-directed bureaucratic regulation. The erosion of medical self-regulation can be attributed to: the pressures of market liberalisation and new public management reforms; changing ideologies and public attitudes towards expertise and risk; and high profile public failures involving doctors. The "new" UK medical regulation converts the General Medical Council into a modern regulator charged with implementing policy, and alters the mechanisms for controlling and directing the conduct and performance of doctors. It establishes a new set of relationships between the medical profession and the state (including its agencies), the public, and patients. This paper adds to the literature by identifying the main features of the reforms affecting the medical profession and offering an analysis of why they have taken place.

  7. Clean Cities Now Vol. 17, No. 1

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-05-24

    Biannual newsletter for the U.S. Department of Energy's Clean Cities initiative. The newsletter includes feature stories on advanced vehicle deployment, idle reduction, and articles on Clean Cities coalition successes across the country.

  8. Building information modelling (BIM: now and beyond

    Directory of Open Access Journals (Sweden)

    Salman Azhar

    2015-10-01

    Full Text Available Building Information Modeling (BIM, also called n-D Modeling or Virtual Prototyping Technology, is a revolutionary development that is quickly reshaping the Architecture-Engineering-Construction (AEC industry. BIM is both a technology and a process. The technology component of BIM helps project stakeholders to visualize what is to be built in a simulated environment to identify any potential design, construction or operational issues. The process component enables close collaboration and encourages integration of the roles of all stakeholders on a project. The paper presents an overview of BIM with focus on its core concepts, applications in the project life cycle and benefits for project stakeholders with the help of case studies. The paper also elaborates risks and barriers to BIM implementation and future trends.

  9. Building information modelling (BIM: now and beyond

    Directory of Open Access Journals (Sweden)

    Salman Azhar

    2012-12-01

    Full Text Available Building Information Modeling (BIM, also called n-D Modeling or Virtual Prototyping Technology, is a revolutionary development that is quickly reshaping the Architecture-Engineering-Construction (AEC industry. BIM is both a technology and a process. The technology component of BIM helps project stakeholders to visualize what is to be built in a simulated environment to identify any potential design, construction or operational issues. The process component enables close collaboration and encourages integration of the roles of all stakeholders on a project. The paper presents an overview of BIM with focus on its core concepts, applications in the project life cycle and benefits for project stakeholders with the help of case studies. The paper also elaborates risks and barriers to BIM implementation and future trends.

  10. Selfies are out - Now we take Healthies

    DEFF Research Database (Denmark)

    Fausing, Bent

    2014-01-01

    This article is about healthy selfies. Images of fit bodies and sweat are the hottest thing in selfies these days. They fit somewhere between recognition and narcissism, says an associate professor and PhD, Bent Fausing, who believes that the fit body is an images of success - and protection...

  11. Clean Cities Now Vol. 17, No. 2

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-10-23

    The Fall 2013 issue of the biannual newsletter for the U.S. Department of Energy's Clean Cities initiative. The newsletter includes feature stories on deployment of alternative fuels and advanced vehicles, and articles on Clean Cities coalition successes across the country.

  12. A Homeland Security Net Assessment Needed Now!

    Science.gov (United States)

    2015-12-01

    George Washington University. Cilluffo argues that the DHS responds to most threats reactively and has only a limited capability for assessing...also the director of the NSA and the two organizations are both located at Fort Meade , Maryland, the two commands have dif- ferent missions and operate...12. 75. David Clark, Thomas Berson, and Herbert S. Lin, eds., At the Nexus of Cybersecurity and Public Policy: Some Basic Concepts and Issues

  13. Blended learning pedagogy: the time is now!

    Science.gov (United States)

    Pizzi, Michael A

    2014-07-01

    Pedagogy is rapidly changing. To develop best practice in academia, it is important that we change with the changing needs of students. This article suggests that blended learning is one of the most important pedagogical formats that can enhance student learning, optimize the use of active learning strategies, and potentially improve student learning outcomes.

  14. Power cables now and in the future

    Energy Technology Data Exchange (ETDEWEB)

    Wanser, G

    1976-01-01

    A survey is presented of the problems to be faced with the underground supply of electric power to large, urban areas and of the contributions that improvements in power cable technology will make to solving these problems. It is concluded that the increase in population densities and the rising demand for energy on the part of individual consumers bring up problems for electricity supply and thus have a direct influence on development trends in cable engineering. During the last few years the increasing capacities required in power transmission have led to the use of higher voltages and to the application of special methods of cooling for the oil-filled cable. When the technical and economic possibilities with present-day cable techniques have been exhausted, we must anticipate the introduction of new types of cable, i.e., gas-insulated cables and superconducting cables. The problems involved in power distribution are being solved successfully by resorting to larger conductor cross-sectional areas and by raising the voltage levels. The advantages of plastic cables are also being utilized on a wide scale. The requirement that there be freedom from partial discharges in plastic cables operating at medium and higher voltages is becoming increasingly more widely adopted as a new quality criterion in cable engineering. New materials from the polymer range are permitting the introduction of fittings which are easier to install and which reduce costs. Cable engineering has already, to a considerable extent, adapted itself to face future problems. Even so, there are still a large number of problems in cable engineering requiring research, development and operation.

  15. The Cold War is Over. What Now?

    Science.gov (United States)

    Hecker, S. S.

    1995-04-01

    As you might imagine, the end of the Cold War has elicited an intense reexamination of the roles and missions of institutions such as the Los Alamos National Laboratory. During the past few years, the entire defense establishment has undergone substantial consolidation, with a concomitant decrease in support for research and development, including in areas such as materials. The defense industry is down-sizing at a rapid pace. Even universities have experienced significant funding cutbacks from the defense community. I view this as a profound time in history, bringing changes encompassing much more than just the defense world. In fact, support for science and technology is being reexamined across the board more completely than at any other time since the end of World War II.

  16. Data processing potential ten years from now

    International Nuclear Information System (INIS)

    Zajde, C.

    1982-01-01

    What today is still experimental will tomorrow be routine. Use of emission tomography, automatic determination of regions of interest, generalisation of Fourrier phase and amplitude analysis, parametric images these will become routine medical protocols. The next ten years will see a saturation in the field of research and a stabilisation in system development. Equipment renewal will be seen from the same angle as in the automotive industry - more for reasons of wear and tear than for reasons of technical advancement

  17. A child abuse research network: Now what?

    Science.gov (United States)

    Lindberg, Daniel M; Scribano, Philip V

    2017-08-01

    As foundational work in preparation for a sustainable, multi-center network devoted to child abuse medical research, we recently used a combination of survey and modified Delphi methodologies to determine research priorities for future multi-center studies. Avoiding missed diagnoses, and improving selected/indicated prevention were the topics rated most highly in terms of research priority. Several constructive commentaries in this issue identify the key challenges which must be overcome to ensure a successful network. Indeed, as with the clinical work of child abuse pediatrics, a scientific network will also require constant collaboration within and outside the community of child abuse pediatricians, the wider medical community, and even non-medical professions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. ArtRank and the Flippers: Apocalypse now?

    NARCIS (Netherlands)

    Velthuis, O.

    2014-01-01

    Despite its professed love for perversion, the art world, it would seem, is quick to moralize when it comes to the rules of buying and selling the objects in which it trades. According to the prevailing order, one must not only have sufficient funds, but first be socialized according to an

  19. Presentation of new features in ServiceNow

    CERN Multimedia

    CERN. Geneva; Mendez Lorenzo, Patricia

    2012-01-01

    We would like to present a few important new features in SNOW like SLAs, new visibility levels, new priority matrix, revised notifications, etc. This will be a one hour presentation with the possibility to raise questions and have on-line demonstrations. Friday 8.6 at 16:00 - 17:00 in the BE Auditorium (B 6-2-024) Hope to see you all, GS and IT Service Management Team

  20. Now arriving at platform 1.. SUPER TRAIN

    CERN Multimedia

    Matthews, Robert

    2008-01-01

    Superconducting materials hold the secret to new high-speed trains and are likely to be thw solution to the pending energy crisis. But they've been around for almost a cnetury, so what are we still waiting for asks. (4 pages)_

  1. Safety and security risk assessments--now demystified!

    Science.gov (United States)

    White, Donald E

    2011-01-01

    Safety/security risk assessments no longer need to spook nor baffle healthcare safety/security managers. This grid template provides at-at-glance quick lookup of the possible threats, the affected people and things, a priority ranking of these risks, and a workable solution for each risk. Using the standard document, spreadsheet, or graphics software already available on your computer, you can easily use a scientific method to produce professional looking risk assessments that get quickly understood by both senior managers and first responders alike!

  2. Clean Cities Now, Vol. 18, No. 1

    Energy Technology Data Exchange (ETDEWEB)

    None

    2014-04-30

    The Spring 2014 edition of the semi-annual newsletter for the U.S. Department of Energy's Clean Cities initiative. The newsletter includes feature stories on deployment of alternative fuels and advanced vehicles, and articles on Clean Cities coalition successes across the country.

  3. From Democracy to Socialism: Then and Now

    NARCIS (Netherlands)

    Raekstad, P.; Panitch, L.; Albo, G.

    2017-01-01

    In recent years, we’ve seen more and more calls for ‘democracy’ – not only among familiar reformist and liberal groups, but from far more radical ones as well. Radical calls for democracy are seen in movements and organizations from the Arab Spring, Occupy, and the Movement of the Squares to the

  4. We Are All Roman Porn Stars Now

    Science.gov (United States)

    Bousquet, Marc

    2012-01-01

    American Association of University Professors (AAUP) members are likely to be familiar with the 1960 adaptation of Howard Fast's "Spartacus" by Stanley Kubrick and Dalton Trumbo, a rousing Kirk Douglas production widely credited with breaking the Hollywood blacklist. They are a bit less likely to be among the five or six million weekly viewers of…

  5. Freedom Now! Radical Jazz and Social Movements

    Directory of Open Access Journals (Sweden)

    Przemysław Pluciński

    2014-01-01

    Full Text Available Music is obviously not only an aesthetic phenomenon. It is embeddedin a dense network of social relations. However, its social involvementis rather ambiguous, particularly since the second half of the twentiethcentury. On the one hand, music is one of the main elements of culturalcapitalism and a part of the system of domination. On the other hand,music provokes, (coproduces or possibly strengthens and coexists witha number of counterdiscourses and social projects of counterhegemoniccharacter.The main objective of the paper is to examine relationships between both, revolutionary jazz and revolutionary social movements, namely the civil rights movement, but above all radical movements, especially black power movement. The crucial questions I am interested in are problems of selforganization, performative social practices, as well as alternatives elaborated by radical-oriented jazz circles in various social dimensions, for instance economic or symbolic.

  6. Consultant breast radiographers: Where are we now?

    International Nuclear Information System (INIS)

    Rees, Zebby

    2014-01-01

    Introduction: The aim of this study is to: • Evaluate the current role of the consultant breast radiographer. • Compare current practice with the four key components for consultant practice. • Gauge the support of radiologist colleagues. • Determine the other professional commitments involved with the role. This study could be the precursor for a macro study of all consultant radiographer practice in other specialities. Methodology: Methodology used was a comparative ethnographic study. Questionnaires to the 24 consultant breast radiographers currently in post, and consultant breast radiologists, who work with them, were conducted. Data collection was a qualitative thematic approach. Conclusion: Consultant breast radiographers provide high quality care to patients through excellent clinical practice, leadership and good communication. However, this study shows hospital Trusts emphasis for non medical consultants is for clinical practice first. Some radiologists are still a barrier to progression for consultant breast radiographers, and radiologists have a big influence in recruitment decisions. Consultant breast radiographer posts are well established, their numbers are increasing through recognition of the role and of their abilities and performance. Consultant breast radiographers state that becoming a consultant is the major achievement of their career, proving the Society of Radiographers' vision of the four-tier career structure has been well received by the radiography profession

  7. Danish desire to harmonise energy taxation now

    International Nuclear Information System (INIS)

    Morch, Stein

    2003-01-01

    International environmental regulation with CO 2 quotas will not be in harmony with continued national tax schemes. Such schemes should be immediately removed or at least coordinated with the other Nordic countries. So far energy and environmental taxes have been of purely national concern, the result of which has been very different prices among the countries. On the wholesale side, the Nordic countries are connected with a well-functioning market with one price as long as net grid capacity is sufficient. But the picture is very different when taxes and subsidies are included. In 2003, the EU passed a directive about CO 2 quotas, which will be implemented in 2005

  8. Parent Involvement, Technology, and Media: Now What?

    Science.gov (United States)

    Patrikakou, Eva N.

    2016-01-01

    The rapid technological advances, the expansion of online media use, and the declining cost of mobile technology have introduced a communication factor that has precipitously affected parent involvement and the relationship between parents and children. The present article explores ways through which technology and online media have affected…

  9. The Cold War is over. What now?

    Energy Technology Data Exchange (ETDEWEB)

    Hecker, S.S.

    1995-05-01

    As you might imagine, the end of the Cold War has elicited an intense reexamination of the roles and missions of institutions such as the Los Alamos National Laboratory. During the past few years, the entire defense establishment has undergone substantial consolidation, with a concomitant decrease in support for research and development, including in areas such as materials. The defense industry is down-sizing at a rapid pace. Even universities have experienced significant funding cutbacks from the defense community. I view this as a profound time in history, bringing changes encompassing much more than just the defense world. In fact, support for science and technology is being reexamined across the board more completely than at any other time since the end of World War II.

  10. Massive-Star Magnetospheres: Now in 3-D!

    Science.gov (United States)

    Townsend, Richard

    Magnetic fields are unexpected in massive stars, due to the absence of a dynamo convection zone beneath their surface layers. Nevertheless, kilogauss-strength, ordered fields were detected in a small subset of these stars over three decades ago, and the intervening years have witnessed the steady expansion of this subset. A distinctive feature of magnetic massive stars is that they harbor magnetospheres --- circumstellar environments where the magnetic field interacts strongly with the star's radiation-driven wind, confining it and channelling it into energetic shocks. A wide range of observational signatures are associated with these magnetospheres, in diagnostics ranging from X-rays all the way through to radio emission. Moreover, these magnetospheres can play an important role in massive-star evolution, by amplifying angular momentum loss in the wind. Recent progress in understanding massive-star magnetospheres has largely been driven by magnetohydrodynamical (MHD) simulations. However, these have been restricted to two- dimensional axisymmetric configurations, with three-dimensional configurations possible only in certain special cases. These restrictions are limiting further progress; we therefore propose to develop completely general three-dimensional models for the magnetospheres of massive stars, on the one hand to understand their observational properties and exploit them as plasma-physics laboratories, and on the other to gain a comprehensive understanding of how they influence the evolution of their host star. For weak- and intermediate-field stars, the models will be based on 3-D MHD simulations using a modified version of the ZEUS-MP code. For strong-field stars, we will extend our existing Rigid Field Hydrodynamics (RFHD) code to handle completely arbitrary field topologies. To explore a putative 'photoionization-moderated mass loss' mechanism for massive-star magnetospheres, we will also further develop a photoionization code we have recently prototyped. Simulation data from these codes will be used to synthesize observables, suitable for comparison with datasets from ground- and space-based facilities. Project results will be disseminated in the form of journal papers, presentations, data and visualizations, to facilitate the broad communication of our results. In addition, we will release the project codes under an open- source license, to encourage other groups' involvement in modeling massive-star magnetospheres. Through furthering our insights into these magnetospheres, the project is congruous with NASA's Strategic Goal 2, 'Expand scientific understanding of the Earth and the universe in which we live'. By making testable predictions of X-ray emission and UV line profiles, it is naturally synergistic with observational studies of magnetic massive stars using NASA's ROSAT, Chandra, IUE and FUSE missions. By exploring magnetic braking, it will have a direct impact on theoretical predictions of collapsar yields, and thereby help drive forward the analysis and interpretation of gamma-ray burst observations by NASA's Swift and Fermi missions. And, through its general contribution toward understanding the lifecycle of massive stars, the project will complement the past, present and future investments in studying these stars using NASA's other space-based observatories.

  11. THE Port: Hackathon at CERN | Apply now!

    CERN Multimedia

    THE Port team

    2014-01-01

    Are you innovative and like to share your ideas with other enthusiasts? Would you like to apply your knowledge and skills to humanitarian problems? Are you motivated to work on issues beneficial to society?   Apply to our problem-solving workshop - also known as hackathon / makeathon - taking place at CERN from 31 October to 2 November. You will work in interdisciplinary teams on topics inspired by other NGOs like ICRC, UN Development Programme, UNOSAT and UNITAR. Example topics are: Virtual tower camera for air fields The conflict zone humanitarian demarcation certificate The 10$ inflatable fridge for field operations Wearable sign language interpreter Can mobile communication data reveal election fraud? Tracking and demarcation system for dogs in rescue and de-mining operations   The 4 teams of 7 hand-picked innovators will be assembled 6 weeks ahead of the event to give time for preparation as some hardware might be needed. In this time they c...

  12. THE Port: Hackathon at CERN | Apply now!

    CERN Multimedia

    THE Port team

    2014-01-01

    Are you innovative and do you like to share your ideas with other enthusiasts? Would you like to apply your knowledge and skills to humanitarian problems? Are you motivated to work on issues beneficial to society?   Apply for our problem-solving workshop - also known as a hackathon / makeathon - taking place at CERN from 31 October to 2 November. You will work in interdisciplinary teams on topics inspired by other NGOs such as the ICRC, UN Development Programme, UNOSAT and UNITAR. Example topics are: Virtual tower camera for air fields The conflict zone humanitarian demarcation certificate The $10 inflatable fridge for field operations Wearable sign language interpreter Can mobile communication data reveal election fraud? Tracking and demarcation system for dogs in rescue and de-mining operations   The four teams of seven hand-picked innovators will be assembled six weeks ahead of the event to give time for preparation as some hardware m...

  13. Sensing with FETs - once, now and future

    NARCIS (Netherlands)

    Olthuis, Wouter; Faber, Erik Jouwert; Krommenhoek, E.E.; van den Berg, Albert; Gerlach, Gerald; Hauptmann, Peter

    2007-01-01

    In this paper a short overview is given of the several FET-based sensor devices and the operational principle of the ISFET is summarized. Some of the shortcomings of the FET sensors were circumvented by an alternative operational mode, resulting in a device capable of acid/base concentration

  14. Long-Acting Antiretrovirals: Where Are We now?

    Science.gov (United States)

    Nyaku, Amesika N; Kelly, Sean G; Taiwo, Babafemi O

    2017-04-01

    Current HIV treatment options require daily use of combination antiretroviral drugs. Many persons living with HIV experience treatment fatigue and suboptimal adherence as a result. Long-acting antiretroviral drugs are being developed to expand options for HIV treatment. Here, we review the agents in development, and evaluate data from recent clinical trials. In addition, we anticipate challenges to successful widespread use of long-acting antiretrovirals. Parenteral nanosuspensions of cabotegravir and rilpivirine, and dapivirine vaginal ring are the farthest in clinical development. Long-acting modalities in earlier development stages employ drug-loaded implants, microparticles, or targeted mutagenesis, among other innovations. Long-acting antiretroviral drugs promise new options for HIV prevention and treatment, and ways to address poor adherence and treatment fatigue. Further studies will identify the long-acting agents or combinations that are suitable for routine use. Creative solutions will be needed for anticipated implementation challenges.

  15. Depleted uranium munitions - where are we now?

    International Nuclear Information System (INIS)

    Spratt, Brian G.

    2002-01-01

    There are very different views on the health hazards of DU munitions. Most of the concerns of veterans and their advisors focus on the radiological effects of DU and consequently these are the focus of this editorial. Effects on the kidney and environmental consequences are, however, considered in the second of the Royal Society reports and the main conclusions of both of the reports are outlined in the summary document published in this issue of the journal. The main radiological concerns focus on the irradiation of lung tissues from inhaled DU particles and irradiation resulting from the translocation of inhaled particles to the thoracic lymph nodes.The overwhelming scientific view, presented in the two Royal Society reports and in other independent reviews, is that the main risks of exposure to DU aerosols are an increase in lung cancer and (from chemical toxicity) damage to the kidney, although these are likely to be evident only following substantial intakes. The equivalent doses to the thoracic lymph nodes following inhalation of DU particles are about ten times greater than those to the lung, but the former tissue is considered to be relatively insensitive to radiation-induced cancers. So far, large-scale epidemiological studies of UK and US Gulf War veterans have shown no increase in mortality from cancer, or kidney disease, but these studies need to be continued to see if any significant excess mortality from these causes appears. As mentioned previously, more sensitive epidemiological studies should be possible if groups of soldiers who have known exposures to DU can be identified. Adverse reproductive effects have been observed in rodents exposed to uranium although most of these effects are evident after relatively large daily intakes of uranium. The possibility of effects on reproductive health (from DU or other toxic exposures) is being studied in both UK and US Gulf War veterans. Results from the UK epidemiological study are not yet available but self-reported birth defects were significantly increased in US Gulf War Veterans compared to a control group. Such studies are subject to reporting bias and confirmation of these results using medical records is required. Finally, there are multiple toxic, or potentially toxic, exposures in modern warfare (particularly during the Gulf War), and the Iraqi population has also been exposed to chemical agents. Thus, even if clear excesses of cancers or birth defects are established, it will be difficult to link them to DU, to any of the other exposures, or to some combination of toxic exposures. However, a clear independent scientific view on whether there are any excesses is a necessary first stage

  16. Maglev transport now and for the future

    Energy Technology Data Exchange (ETDEWEB)

    Kawashima, Maumi

    1987-09-01

    Maglef transport is transport characterized by the use of magnetic force to support and guide vehicles. Vehicles appear to be elevated because they are supported by magnetic force. The magnets used for maglef transport are permanent magnets, superconducting magnets, and electromagnets. The feature of maglef transport are as follows: (1) high speed and ease in selecting routes, (2) low noise, (3) low vibration, (4) little need for maintenance, and (5) energy saving. The development of maglef transport entered the stage of practical use in the 1970s. Since problems concerning development cost are involved, the countries where maglef transport is practically used or is being developed for practical use are only Japan, West Germany, and the United Kingdom. In Japan, the Japan National Railway began to study linear motor driven maglef transport in the 1960s and started tests with the LMU-002, which is a 44-seat practical-size vehicle with a capacity of 70 to 80 passengers, in April, 1987. Study for maglef transport meeting social needs is expected to advance. (16 figs, 2 tabs, 10 refs)

  17. The mind: psychoanalytic understanding then and now.

    Science.gov (United States)

    Bergmann, Martin S

    2008-01-01

    The author discusses the evolution of psychoanalytic understanding from Freud's time to the present, citing the influence of various sociocultural changes. He addresses Freud's proper place in history and notes ways in which Freud's contributions cast him as belonging to Romanticism. Freud's shift from the topographic model of the mind to the structural one, and the influence of this on psychoanalysis, is discussed, as well as important developments in the field since Freud. The author focuses particularly on difficulties encountered in psychoanalytic practice today, and he describes what he has termed organizing interpretations as uniquely valuable in the treatment setting.

  18. Looked at Life from Both Sides Now

    Directory of Open Access Journals (Sweden)

    Jillian E. Smith

    2014-12-01

    Full Text Available As the molecular top–down causality emerging through comparative genomics is combined with the bottom–up dynamic chemical networks of biochemistry, the molecular symbiotic relationships driving growth of the tree of life becomes strikingly apparent. These symbioses can be mutualistic or parasitic across many levels, but most foundational is the complex and intricate mutualism of nucleic acids and proteins known as the central dogma of biological information flow. This unification of digital and analog molecular information within a common chemical network enables processing of the vast amounts of information necessary for cellular life. Here we consider the molecular information pathways of these dynamic biopolymer networks from the perspective of their evolution and use that perspective to inform and constrain pathways for the construction of mutualistic polymers.

  19. Monitoring Molecules in Neuroscience Then and Now.

    Science.gov (United States)

    Rice, Margaret E

    2017-02-15

    The 16th International Conference on Monitoring Molecules in Neuroscience (MMiN) was held in Gothenburg, Sweden in late spring 2016. This conference originated as a methods meeting focused on in vivo voltammetric techniques and microdialysis. Over time, however, the scope has evolved to include a number of other methods for neurochemical detection that range from single-cell fluorescence in vitro and in vivo in animal models to whole-brain imaging in humans. Overall, MMiN provides a unique forum for introducing new developments in neurochemical detection, as well as for reporting exciting neurobiological insights provided by established and novel methods. This Viewpoint includes a brief history of the meeting, factors that have contributed its evolution, and some highlights of MMiN 2016.

  20. Laser space debris removal: now, not later

    Science.gov (United States)

    Phipps, Claude R.

    2015-02-01

    Small (1-10cm) debris in low Earth orbit (LEO) are extremely dangerous, because they spread the breakup cascade depicted in the movie "Gravity." Laser-Debris-Removal (LDR) is the only solution that can address both large and small debris. In this paper, we briefly review ground-based LDR, and discuss how a polar location can dramatically increase its effectiveness for the important class of sun-synchronous orbit (SSO) objects. No other solutions address the whole problem of large ( 1000cm, 1 ton) as well as small debris. Physical removal of small debris (by nets, tethers and so on) is impractical because of the energy cost of matching orbits. We also discuss a new proposal which uses a space-based station in low Earth orbit (LEO), and rapid, head-on interaction in 10- 40s rather than 4 minutes, with high-power bursts of 100ps, 355nm pulses from a 1.5m diameter aperture. The orbiting station employs "heat-capacity" laser mode with low duty cycle to create an adaptable, robust, dualmode system which can lower or raise large derelict objects into less dangerous orbits, as well as clear out the small debris in a 400-km thick LEO band. Time-average laser optical power is less than 15kW. The combination of short pulses and UV wavelength gives lower required energy density (fluence) on target as well as higher momentum coupling coefficient. This combination leads to much smaller mirrors and lower average power than the ground-based systems we have considered previously. Our system also permits strong defense of specific assets. Analysis gives an estimated cost of about 1k each to re-enter most small debris in a few months, and about 280k each to raise or lower 1-ton objects by 40km. We believe it can do this for 2,000 such large objects in about four years. Laser ablation is one of the few interactions in nature that propel a distant object without any significant reaction on the source.

  1. IRIS COLOUR CLASSIFICATION SCALES--THEN AND NOW.

    Science.gov (United States)

    Grigore, Mariana; Avram, Alina

    2015-01-01

    Eye colour is one of the most obvious phenotypic traits of an individual. Since the first documented classification scale developed in 1843, there have been numerous attempts to classify the iris colour. In the past centuries, iris colour classification scales has had various colour categories and mostly relied on comparison of an individual's eye with painted glass eyes. Once photography techniques were refined, standard iris photographs replaced painted eyes, but this did not solve the problem of painted/ printed colour variability in time. Early clinical scales were easy to use, but lacked objectivity and were not standardised or statistically tested for reproducibility. The era of automated iris colour classification systems came with the technological development. Spectrophotometry, digital analysis of high-resolution iris images, hyper spectral analysis of the human real iris and the dedicated iris colour analysis software, all accomplished an objective, accurate iris colour classification, but are quite expensive and limited in use to research environment. Iris colour classification systems evolved continuously due to their use in a wide range of studies, especially in the fields of anthropology, epidemiology and genetics. Despite the wide range of the existing scales, up until present there has been no generally accepted iris colour classification scale.

  2. Bolder science needed now for protected areas.

    Science.gov (United States)

    Watson, James E M; Darling, Emily S; Venter, Oscar; Maron, Martine; Walston, Joe; Possingham, Hugh P; Dudley, Nigel; Hockings, Marc; Barnes, Megan; Brooks, Thomas M

    2016-04-01

    Recognizing that protected areas (PAs) are essential for effective biodiversity conservation action, the Convention on Biological Diversity established ambitious PA targets as part of the 2020 Strategic Plan for Biodiversity. Under the strategic goal to "improve the status of biodiversity by safeguarding ecosystems, species, and genetic diversity," Target 11 aims to put 17% of terrestrial and 10% of marine regions under PA status by 2020. Additionally and crucially, these areas are required to be of particular importance for biodiversity and ecosystem services, effectively and equitably managed, ecologically representative, and well-connected and to include "other effective area-based conservation measures" (OECMs). Whereas the area-based targets are explicit and measurable, the lack of guidance for what constitutes important and representative; effective; and OECMs is affecting how nations are implementing the target. There is a real risk that Target 11 may be achieved in terms of area while failing the overall strategic goal for which it is established because the areas are poorly located, inadequately managed, or based on unjustifiable inclusion of OECMs. We argue that the conservation science community can help establish ecologically sensible PA targets to help prioritize important biodiversity areas and achieve ecological representation; identify clear, comparable performance metrics of ecological effectiveness so progress toward these targets can be assessed; and identify metrics and report on the contribution OECMs make toward the target. By providing ecologically sensible targets and new performance metrics for measuring the effectiveness of both PAs and OECMs, the science community can actively ensure that the achievement of the required area in Target 11 is not simply an end in itself but generates genuine benefits for biodiversity. © 2016 Society for Conservation Biology.

  3. And now, a word from our sponsor.

    Science.gov (United States)

    Peebles, M Ellen

    2003-10-01

    Bryant Pharmaceutical's flagship product, a popular arthritis medicine called Seflex, is selling well--but not well enough. With generic versions due on the shelves in a couple of years, the drug company is looking for a dramatic sales increase. No wonder marketing VP Laura Goldenberg feels the pressure. She knows she has to reach more consumers, but in an environment where people bombarded with advertising are using devices such as TiVo to skip ads, her job has suddenly taken on a new intensity. In search of a new, gangbuster campaign, Laura and her ad agency come up with the idea of product placement--not your typical integration of a product into a television or movie script, but a less traditional approach. Their idea is to hire a much-loved, elderly actress to extol the virtues of Seflex on a morning news program. The news segment would be about arthritis, and Seflex would be casually mentioned during the interview. The company would have to pay the actress $1 million, and there are risks: What if it gets out that Bryant is paying her? What if the actress errs and says something about Seflex's side effects? If something goes wrong, Bryant Pharmaceutical's reputation could suffer. Should the company green-light Laura's plan? This fictional case study looks at the pros and cons of traditional product placement and newer, more subtle alternatives to advertising. Commenting on the case are Bob Gamgort, president of Masterfoods USA; Michelle R. Nelson, an assistant professor of journalism and mass communications at the University of Wisconsin, Madison; FTC commissioner Mozelle W. Thompson; and Mike Sheehan, president and CEO of Hill, Holliday, Connors, Cosmopulos.

  4. Neuroanesthesia and neuroprotection: where are we now?

    Institute of Scientific and Technical Information of China (English)

    XIONG Li-ze

    2006-01-01

    @@ Neurosurgery especially intracranial surgery is characterized by periods of intense stimulation alternating with periods of minimal pain.Manipulation of the brain itself is not painful to the patient, but the scalp, skull, and meninges are well innervated with pain fibers. Traction on cerebral arteries as well as sensory cranial nerves can be painful. Therefore, the most appropriate choice of drugs or measures for neuroanesthesia should be dependent on a clear understanding of the pharmacological effects of anesthetics as well as the requirements for anesthesia/analgesia in general and the individual neurosurgical case. Besides, the ultimate aim of neuroanesthesia is to provide optimal intracranial operating conditions, maintain an appropriate cerebral hemodynamics to ensure enough cerebral perfusion, protect against ischemic insults and prevent postoperative complications. The anesthetic techniques and the anesthetics used in neuroanesthesia are all geared to these objectives.The changes of neuroanesthesia that have occurred in the past decades show a steady evolution of anesthetic care both in the operating room and the neurocritical care setting.

  5. The Porter Stemming Algorithm: Then and Now

    Science.gov (United States)

    Willett, Peter

    2006-01-01

    Purpose: In 1980, Porter presented a simple algorithm for stemming English language words. This paper summarises the main features of the algorithm, and highlights its role not just in modern information retrieval research, but also in a range of related subject domains. Design/methodology/approach: Review of literature and research involving use…

  6. Derrida's Right to Philosophy, Then and Now

    Science.gov (United States)

    Willinsky, John

    2009-01-01

    In this essay, a tribute to Jacques Derrida's educational efforts at expanding access to current work in philosophy, John Willinsky examines his efforts as both a public right and an element of academic freedom that bear on the open access movement today. Willinsky covers Derrida's extension and outreach work with the Groupe de Recherches pour…

  7. Treatment of Acute Diarrhoea: Past and Now

    Directory of Open Access Journals (Sweden)

    Giuseppe Caramia

    2015-11-01

    Full Text Available Context: Since ancient times diarrhoea has been a highly fatal disease and even today diarrhoea, the topic of this review, is a problem affecting millions of people around the world despite the efforts of governments and professionals from the medical area. Worldwide the most common cause of children’s death is diarrhoea. Evidence Acquisition: Diarrhoea disorders generally appear with watery stools, sometimes mixed with blood, accompanied by abdominal pain, vomiting and fever. The symptoms depend on the content and distribution of body fluid, daily water requirements and physiological water loss in connection with age through sweating, urination and breathing, the degree of fluid and electrolyte loss in the liquid stool. Results: Several effective interventions have been introduced as part of diarrhoea management in the last two decades such as oral rehydration solution, zinc supplementation, vitamin A supplementation and oral administration of antibiotics and vaccines. To reduce the mortality rate, control of safe drinking water, good sanitation and vaccination against typhoid and cholera are recommended, especially in high-risk populations. Probiotics have been proposed, after more than a half of century, as additional therapy in the treatment of acute diarrhoea. Several probiotic strains showed benefit in meta-analyses of randomised controlled trials. Conclusions: Due to the high level of evidence available, the term "oral bacterio therapy", used for decades in the prevention and the rapyof gastroenteritis in the growing age and adults, has expanded, but probiotics are acquiring significant scientific value based on theresults from human trials. The future of probiotics depends on further explanation/elucidation of basic mechanisms, allowing scientists and physicians to maximize their health benefits.

  8. Extra-Articular Manifestations of Rheumatoid Arthritis, Now

    Directory of Open Access Journals (Sweden)

    Paloma Vela

    2014-06-01

    Full Text Available Rheumatoid arthritis (RA is a chronic systemic inflammatory disease, characterised by polyarthritis and extra-articular organ disease, including rheumatoid nodules, ophthalmologic manifestations, cardiopulmonary disease, vasculitis, neuropathy, glomerulonephritis, Felty’s syndrome, and amyloidosis. Extra-articular manifestations of RA (ExRA occur in 17.8–40.9% of RA patients, 1.5–21.5% of them presenting as severe forms and usually associated with increased morbidity and mortality. They can develop at any time during the course of the disease, even in the early stages, and are associated with certain predisposing factors, such as the presence of rheumatoid factor, smoking, and long-standing severe disease. Rheumatoid nodules, the most common ExRA, have been found to be associated with the development of severe features, such as vasculitis, rheumatoid lung disease, pericarditis, and pleuritis, especially in those patients who develop them within 2 years from RA diagnosis. There is no uniformity in the definition of the term ExRA, which limits comparability between different studies. Several recent surveys suggest a lower frequency, probably due to a better control of disease activity. Diagnosis of ExRA is a challenge for clinicians, given its variable and complex presentation, and the lack of specific diagnostic tests; it must be based on clinical recognition and exclusion of other causes of the signs and symptoms. Furthermore, management continues to be difficult with a bad prognosis in many conditions. This article reviews the clinical aspects of major ExRA, focusing on incidence, clinical features, and therapeutic approaches, and how modern immunosuppressive therapy can change the outcome.

  9. Review your Computer Security Now and Frequently!

    CERN Multimedia

    IT Department

    2009-01-01

    The start-up of LHC is foreseen to take place in the autumn and we will be in the public spotlight again. This increases the necessity to be vigilant with respect to computer security and the defacement of an experiment’s Web page in September last year shows that we should be particularly attentive. Attackers are permanently probing CERN and so we must all do the maximum to reduce future risks. Security is a hierarchical responsibility and requires to balance the allocation of resources between making systems work and making them secure. Thus all of us, whether users, developers, system experts, administrators, or managers are responsible for securing our computing assets. These include computers, software applications, documents, accounts and passwords. There is no "silver bullet" for securing systems, which can only be achieved by a painstaking search for all possible vulnerabilities followed by their mitigation. Additional advice on particular topics can be obtained from the relevant I...

  10. Then and Now: Black Boycott in Waterloo.

    Science.gov (United States)

    Anderson, Ruth B.

    1983-01-01

    Discusses events following the desegregation of Waterloo, Iowa, schools. Describes the 1978 Black boycott of Hoover Junior High, which led to improvements in the treatment of Black students. Lists administrative responses to each Black grievance, and presents interviews with ten Black students three years after the boycott. (KH)

  11. Now day methods for heavy ion monitoring

    International Nuclear Information System (INIS)

    Luk'yanov, S.M.; Penionzhkevich, Yu.Eh.; Chubaryan, G.G.

    1984-01-01

    Up-to-date methods for identification of products yield as a result of heavy ion interaction with nuclei are described. Monitoring of total ionization has been realized by gas-filled ionization chambers semiconductor detectors, scintillators. A method for specific ionization loss monitoring and time-of-flight technique for heavy-ion mass identification are considered. Advantages of the method for identification of nuclear reaction prodUcts by means of a magnetic analyzer are displayed

  12. External GSM phone calls now made simpler

    CERN Multimedia

    2007-01-01

    On 2 July, the IT/CS Telecom Service introduced a new service making external calls from CERN GSM phones easier. A specific prefix is no longer needed for calls outside CERN. External calls from CERN GSM phones are to be simplified. It is no longer necessary to use a special prefix to call an external number from the CERN GSM network.The Telecom Section of the IT/CS Group is introducing a new system that will make life easier for GSM users. It is no longer necessary to use a special prefix (333) to call an external number from the CERN GSM network. Simply dial the number directly like any other Swiss GSM customer. CERN currently has its own private GSM network with the Swiss mobile operator, Sunrise, covering the whole of Switzerland. This network was initially intended exclusively for calls between CERN numbers (replacing the old beeper system). A special system was later introduced for external calls, allowing them to pass thr...

  13. Now you see it, now you don’t: The context dependent nature of category-effects in visual object recognition

    DEFF Research Database (Denmark)

    Gerlach, Christian; Toft, Kristian Olesen

    2011-01-01

    In two experiments, we test predictions regarding processing advantages/disadvantages for natural objects and artefacts in visual object recognition. Varying three important parameters*degree of perceptual differentiation, stimulus format, and stimulus exposure duration*we show how different......-effects are products of common operations which are differentially affected by the structural similarity among objects (with natural objects being more structurally similar than artefacts). The potentially most important aspect of the present study is the demonstration that category-effects are very context dependent...

  14. Britain's delegation to CERN, the European Centre for Nuclear Research near Geneva, voted in favour of a project which take seven years to build, involve a 27 kilometre long tunnel, and cost 230 million pounds. Now LEP receives the go-ahead later this month

    CERN Multimedia

    Llewellyn Smith, Christopher Hubert

    1981-01-01

    Britain's delegation to CERN, the European Centre for Nuclear Research near Geneva, voted in favour of a project which take seven years to build, involve a 27 kilometre long tunnel, and cost 230 million pounds. Now LEP receives the go-ahead later this month

  15. RecoverNow: Feasibility of a Mobile Tablet-Based Rehabilitation Intervention to Treat Post-Stroke Communication Deficits in the Acute Care Setting.

    Science.gov (United States)

    Mallet, Karen H; Shamloul, Rany M; Corbett, Dale; Finestone, Hillel M; Hatcher, Simon; Lumsden, Jim; Momoli, Franco; Shamy, Michel C F; Stotts, Grant; Swartz, Richard H; Yang, Christine; Dowlatshahi, Dar

    2016-01-01

    Approximately 40% of patients diagnosed with stroke experience some degree of aphasia. With limited health care resources, patients' access to speech and language therapies is often delayed. We propose using mobile-platform technology to initiate early speech-language therapy in the acute care setting. For this pilot, our objective was to assess the feasibility of a tablet-based speech-language therapy for patients with communication deficits following acute stroke. We enrolled consecutive patients admitted with a stroke and communication deficits with NIHSS score ≥1 on the best language and/or dysarthria parameters. We excluded patients with severe comprehension deficits where communication was not possible. Following baseline assessment by a speech-language pathologist (SLP), patients were provided with a mobile tablet programmed with individualized therapy applications based on the assessment, and instructed to use it for at least one hour per day. Our objective was to establish feasibility by measuring recruitment rate, adherence rate, retention rate, protocol deviations and acceptability. Over 6 months, 143 patients were admitted with a new diagnosis of stroke: 73 had communication deficits, 44 met inclusion criteria, and 30 were enrolled into RecoverNow (median age 62, 26.6% female) for a recruitment rate of 68% of eligible participants. Participants received mobile tablets at a mean 6.8 days from admission [SEM 1.6], and used them for a mean 149.8 minutes/day [SEM 19.1]. In-hospital retention rate was 97%, and 96% of patients scored the mobile tablet-based communication therapy as at least moderately convenient 3/5 or better with 5/5 being most "convenient". Individualized speech-language therapy delivered by mobile tablet technology is feasible in acute care.

  16. Former military officers from the Republic of Vietnam now living in the united states (US): exploring their perceptions of the US healthcare system.

    Science.gov (United States)

    Stephens, Elisabeth K; Nguyen, Phuong L; Radecki Breitkopf, Carmen; Jatoi, Aminah

    2011-12-01

    Few studies have focused on perceptions of healthcare among Vietnamese who came to the United States (US) as refugees. A 48-item survey that included information on demographics, health status, and satisfaction with healthcare [including the Patient Satisfaction Questionnaire-18 (PSQ-18)] was sent to 49 former Vietnamese military officers, who are now living in the US, based on their current geographic residence. A total of 22 of 49 delivered questionnaires were completed and returned, yielding a response rate of 45%. The survey was sent in Vietnamese and English, and all except one was completed in Vietnamese. In response to "Language barriers have prevented me from accessing health care when I need it," 77% of respondents acknowledged that this was "sometimes" the case even today. Most respondents otherwise viewed the healthcare system favorably, but cost concerns were an issue: 28% strongly agreed or agreed with the statement, "I have to pay for more of my medical care than I can afford." In contrast, only 9% described that they would have strongly agreed or agreed to this statement upon first arriving to the US. Write-in comments revealed themes that centered on language barriers, favorable impressions of healthcare in the US, financial concerns, and patriotism towards the US. Further study of this aging population of Vietnamese Americans might help shed light on concerns faced by other refugee populations who have arrived more recently.

  17. "Now I see it, now I don't": Determining Threshold Levels of Facial Emotion Recognition for Use in Patient Populations.

    Science.gov (United States)

    Chiu, Isabelle; Gfrörer, Regina I; Piguet, Olivier; Berres, Manfred; Monsch, Andreas U; Sollberger, Marc

    2015-08-01

    The importance of including measures of emotion processing, such as tests of facial emotion recognition (FER), as part of a comprehensive neuropsychological assessment is being increasingly recognized. In clinical settings, FER tests need to be sensitive, short, and easy to administer, given the limited time available and patient limitations. Current tests, however, commonly use stimuli that either display prototypical emotions, bearing the risk of ceiling effects and unequal task difficulty, or are cognitively too demanding and time-consuming. To overcome these limitations in FER testing in patient populations, we aimed to define FER threshold levels for the six basic emotions in healthy individuals. Forty-nine healthy individuals between 52 and 79 years of age were asked to identify the six basic emotions at different intensity levels (25%, 50%, 75%, 100%, and 125% of the prototypical emotion). Analyses uncovered differing threshold levels across emotions and sex of facial stimuli, ranging from 50% up to 100% intensities. Using these findings as "healthy population benchmarks", we propose to apply these threshold levels to clinical populations either as facial emotion recognition or intensity rating tasks. As part of any comprehensive social cognition test battery, this approach should allow for a rapid and sensitive assessment of potential FER deficits.

  18. RecoverNow: Feasibility of a Mobile Tablet-Based Rehabilitation Intervention to Treat Post-Stroke Communication Deficits in the Acute Care Setting.

    Directory of Open Access Journals (Sweden)

    Karen H Mallet

    Full Text Available Approximately 40% of patients diagnosed with stroke experience some degree of aphasia. With limited health care resources, patients' access to speech and language therapies is often delayed. We propose using mobile-platform technology to initiate early speech-language therapy in the acute care setting. For this pilot, our objective was to assess the feasibility of a tablet-based speech-language therapy for patients with communication deficits following acute stroke.We enrolled consecutive patients admitted with a stroke and communication deficits with NIHSS score ≥1 on the best language and/or dysarthria parameters. We excluded patients with severe comprehension deficits where communication was not possible. Following baseline assessment by a speech-language pathologist (SLP, patients were provided with a mobile tablet programmed with individualized therapy applications based on the assessment, and instructed to use it for at least one hour per day. Our objective was to establish feasibility by measuring recruitment rate, adherence rate, retention rate, protocol deviations and acceptability.Over 6 months, 143 patients were admitted with a new diagnosis of stroke: 73 had communication deficits, 44 met inclusion criteria, and 30 were enrolled into RecoverNow (median age 62, 26.6% female for a recruitment rate of 68% of eligible participants. Participants received mobile tablets at a mean 6.8 days from admission [SEM 1.6], and used them for a mean 149.8 minutes/day [SEM 19.1]. In-hospital retention rate was 97%, and 96% of patients scored the mobile tablet-based communication therapy as at least moderately convenient 3/5 or better with 5/5 being most "convenient".Individualized speech-language therapy delivered by mobile tablet technology is feasible in acute care.

  19. Exploitation of "Excess" Data Now Routinely Collected by Large N, Continuously Recorded Oil Exploration Surveys: From Microseismicity to Deep Crustal Imaging

    Science.gov (United States)

    Brown, L. D.

    2014-12-01

    The rapidly expanding use by the oil and gas industry of "nodal", large channel capacity areal arrays that record continuously for extended periods of time is generating large volumes of data in excess of that needed for the conventional CMP reflection imaging that is the primary goal of such surveys. These excess data, once considered as simply "noise", have recently been recognized to have utility not only for the exploration seismologist but also for addressing a diverse range of phenomena. The most widely recognized use for these "noise" records is surface wave tomographic imaging of near surface velocity structure via seismic interferometry of ambient natural noise. Such results are proving to be of great value in enhancing conventional 3D exploration imagery, but they should be appreciated in their own right for the information they provide on the shallow subsurface to the hydrologist, engineer and tectonicist. Another relatively dramatic application is the delineation of local structure by tracing the propagation of body and surface waves from local and teleseismic events across these dense arrays. Here I would like draw attention to three other promising uses for such data: a) detection and mapping of microseismicity below the detection thresholds of conventional earthquake monitoring networks, especially in areas of low conventional seismicity; b) reflection and refraction imaging of structure using cultural, as opposed to natural, energy sources, and c) systematic mapping of the basement in 3D using the existing exploration sources recorded at travel times longer than that typically harvested for resource purposes. We conclude by emphasizing that these potentially invaluable "extras" are now being recorded routinely around the world, but there is as yet no mechanism in place to ensure they are exploited rather than simply deleted.

  20. New EN standards for flanges and weld-on fittings now in force. Tricky in the detail, but design of a pipeline entirely in conformity to European codes and standards is possible; Neue EN-Normen fuer Flansche und Schweissfittings in Kraft. Tuecken im Detail, aber die Konstruktion einer Rohrleitung komplett nach Europaeischem Regelwerk wird moeglich

    Energy Technology Data Exchange (ETDEWEB)

    Willauschus, A. [BUHLMANN Rohr-Fittings-Stahlhandel GmbH und Co. KG, Hilden (Germany)

    2008-07-15

    The second edition of EN 1092, Part 1, 'Circular steel flanges', with date of issue November, 2007, the calculation rules of which are now based on the Woelfel-formulae, is now in force. This new edition had become necessary because the June 2002 edition was, indeed, based on EN 1591 as a calculation tool, but only flanges up to DN 600 had been calculated. Rapid establishment of the new EN 1092, Part 1, on the market can be anticipated following this new edition, since the new pipe classes of the chemicals industry, published in PAS 1057, are based on the new EN 1092, Part 1, and BASF has now also become the first major chemicals corporation to convert its flange ordering to this EN standard, starting in early 2008. From 2009 onward, all other major chemicals companies, which drafted PAS 1057 jointly in the 'Pipelines Working Committee' within the 'Process-Engineering Corporation of BDI', will successively follow. The 'Specialist Confederation for Steel Flanges' is also already working on a new flange catalogue based on EN 1092, Part 1. (orig.)

  1. The tar sands of the USA : with permits now in hand, a Calgary company is a cash injection away from producing oil from America's first oilsands mine

    Energy Technology Data Exchange (ETDEWEB)

    Jaremko, D.

    2010-06-15

    A Canadian company has recently received approval to develop large oil sands mining operations in Utah. Earth Energy Resources is now raising the finances required to commercialize its operations in the state. Utah's oil sands reserves are currently estimated at between 20 to 32 billion barrels. However, the impacts of oil sands operations are of concern to some environmental groups, who worry that Utah will become a duplicate of Alberta's Athabasca region. The planned project is a 2000 barrel-per-day pilot project. Regulators in Utah have received negative responses from the public after advertising the potential project in local newspapers, and demonstrations have been held in the state's capital. Oil sands are already being developed at 2 installations in Utah, with the bitumen currently being sold as asphalt products. The state is also home to significant oil shale reserves. Operators in the region plan to design compact, well-contained mines in order to maintain transportability. 3 figs.

  2. Plan now to make your retirement active, productive.

    Science.gov (United States)

    Schlepp, S

    1989-12-01

    In his book Planning to the Years Ahead, Lester I. Tenney, PhD, professor emeritus at Arizona State University, Tempe, links Abraham Maslow's hierarchy of needs to retirement planning. According to Maslow, economic and security needs can be achieved through a family environment (eg, food clothing, shelter), and social acceptance, self-worth, and self-satisfaction can be achieved from social interaction, work, or leisure activities. After the basic needs of food, clothing, and shelter have been achieved, people are able to move to the next level of achieving safety and security. The level of dependency that people have on satisfying these needs through work will determine how well they are at adapting to retirement. The more people depend on work alone, the harder will be the adjustment; people who are less dependent on work will find retirement easier to accept.

  3. SEWGS Technology is Now Ready for Scale-up

    Energy Technology Data Exchange (ETDEWEB)

    Jansen, D.; Van Selow, E.; Cobden, P. [Energy research Centre of the Netherlands ECN (Netherlands); Manzolini, G.; Macchi, E.; Gazzani, M. [Politecnico di Milano PTM, Dipartimento di Energia (Italy); Blom, R.; Henriksen, P.P. [SINTEF, Trondheim (Norway); Beavis, R. [BP Alternative Energy (United Kingdom); Wright, A. [Air products PLC (United Kingdom)

    2013-07-01

    In the FP7 project CAESAR, Air Products, BP, ECN, SINTEF and Politecnico di Milano worked together in the further development of the SEWGS process with the objective to reduce the energy penalty and the costs per ton of CO2 avoided to less than 25 euro through optimization of sorbent materials, reactor and process design and smart integration of the SEWGS unit in a combined cycle power plant. The most promising applications for the SEWGS technology are IGCC power plants and in combined cycles power plants fuelled with blast furnace top gas. Extensive sorbent development work resulted in a new sorbent called ALKASORB+ with a high capacity resulting in cost of CO2 avoided for the IGCC application of 23 euro. This is a reduction of almost 40% compared to the Selexol capture case. Since ALKASORB+ requires much less steam in the regeneration, the specific primary energy consumption is reduced to 44% below the specific energy consumption for the Selexol (2.08 versus 3.71 MJLHV/kgCO2). From a technical point of view SEWGS is ready to move to the next development level, which is a pilot plant installation with a capacity of 35 ton CO2 per day. This is over 500 times larger than the current ECN's multi column SEWGS installation, but still 50 times smaller than an envisaged commercial scale installation. The pilot plant will prove the technology under field conditions and at a sufficiently large scale to enable further up-scaling, delivering both the basic design and investment costs of a full scale SEWGS demonstration plant.

  4. Book Swap Now Open to All Employees | Poster

    Science.gov (United States)

    Not only did the year 2000 mark the start of a new millennium, the beginning of the Human Genome Project, and the opening of the International Space Station, but it was also the first year that the Scientific Library held its annual Book & Media Swap. Starting Nov. 12, the 15th annual Book Swap is open to all NCI at Frederick employees.

  5. Five-yearly review: where do we stand now?

    CERN Multimedia

    Staff Association

    2016-01-01

    A reminder The first issue of Echo in 2016 announced a year of changes with many challenges for the Staff Association and the staff it represents. Indeed, following the decision of the Council in December 2015 to approve all components of the five-yearly review, many changes were to be implemented in 2016. This is the case of the new career structure, the definition of benchmark jobs (BMJ), the redesign of the advancement and promotions process, etc. Looking back at 2015 and the various statements In December 2015, the CERN Council emphasized: the substantial effort made by the Staff Association and the Management, taking into account the difficult economic situation faced by some Member States, led to the creation of a package of measures as balanced as possible. It is clear however: that there was no alignment of CERN basic salaries with the comparison salaries; that in the new career system, staff will have their advancement prospects, and consequently the level of their pension, reduced with respect to ...

  6. Caught in Uncertain Futures, Now: A Reflexive Moment

    Science.gov (United States)

    Reyes, Reynaldo, III

    2016-01-01

    This reflexive vignette reveals the emotional risks of ethnographic work by a Chicano researcher, educator, and advocate doing work in the Texas-Mexico Borderlands, caught at the intersection of vulnerable Latina/o youth and their possible futures. Data in this creative piece are derived from field notes of one classroom observation from an…

  7. Now is the time for the Zika virus

    Directory of Open Access Journals (Sweden)

    Salim Mattar V

    2015-05-01

    Full Text Available In April 1947 it was discovered through an experimental animal model a jungle fever. During the experiment, monkeys (macaques were placed in cages and left exposed in the Zika forest (Uganda; one of the monkeys became ill and died. They filtered postmortem monkey tissues were inoculated into mouse brain and from there, a virus called Zika (ZIKV was cultured. In 1948 ZIKV was also isolated from mosquitoes Aedes africanus captured in the Zika forest. In 1956 ZIKV transmission in mosquitoes Ae. aegypti was found, as well as a monkey. Between 1968 and 1975, ZIKV was subsequently isolated from humans (Nigeria; 40% of those patients analized by PRNT shown antibodies (1.

  8. And now for the good news [nuclear energy

    International Nuclear Information System (INIS)

    Robertson, J.A.L.

    1984-01-01

    When specialists get together to discuss their subject, they usually concentrate on their problems. This, if done constructively, can be useful, but it provides outsiders with an unbalanced view of the subject. The problems are then amplified by the media, which provide much better coverage of bad news than good news. For instance, in papers on global energy, economists have stressed the difficulties in raising capital, not only for new energy systems but for any worthwhile project. Restating the problem is no help; what is needed of economists are solutions. Fortunately, for the technical problems of energy supply, there are solutions, one of which is nuclear energy. Futhermore, some of the solutions are not just economically acceptable, they could be economically beneficial

  9. The Time is Now: Legislation for the Interagency

    Science.gov (United States)

    2012-05-17

    71 Gabriel Marcella , “National Security and the Interagency Process: Forward into the 21st Century... Marcella , Gabriel, National Security and the Interagency Process: Forward into the 21st Century, “Organizing for National Security,” ed. Douglas T

  10. Facebook, Twitter, Instagram, Pinterest – nowe perspektywy badawcze

    OpenAIRE

    Maria Czarkowska; Anna Gumkowska

    2017-01-01

    Facebook, Twitter, Instagram, Pinterest – new research perspectivesThe goal of this paper is to present the vast array of content that is emerging within social media platforms: Facebook, Twitter, Instagram and Pinterest and analyze the ways in which they can be classified. This is a review of the available interdisciplinary methods and factors that should be taken into consideration when researching the genelogy of the texts that arise in the network. The Internet has changed the face of soc...

  11. Then and now with utility advertising and marketing

    Energy Technology Data Exchange (ETDEWEB)

    Netschert, B.C.

    1978-11-09

    Basic business functions, such as advertising and marketing, occupy a valid place in the lives of public utilities, even in an environment where conservation and economy are emphasized. The author describes how a particular group of electric-utility companies has changed emphasis in an exemplary response to new societal pressures and values. He identifies the litmus test of the appropriateness of promotional and information activities and expenditures by utilities in terms of consumer sovereignty.

  12. Mild Cognitive Impairment: What Do We Do Now?

    Science.gov (United States)

    ... Human Development and Family Science Modern and Classical Languages and Literatures Philosophy Political Science Religion and Culture Reserve Officer Training Corps Airforce Reserve Officer Training ...

  13. The year of political advertising - now! / Marius Vaupsas

    Index Scriptorium Estoniae

    Vaupsas, Marius

    2004-01-01

    BBDO Lukrecijos Reklama juht prognoosib 2004. aastat Leedu reklaamiturul, poliitilisest reklaamist, poliitikute ja reklaamispetsialistide vahelistest suhetest ning reklaamiagentuuride rollist poliitilistes valimiskampaaniates. Lisa: Some examples of successful cooperation

  14. GSM accessories now available from the CERN Stores

    CERN Multimedia

    Labo Telecom

    2001-01-01

    As of 1st October you can order and receive GSM accessories from the CERN stores like any other article. The CERN stores also manage GSM telephones but, for technical reasons, only the Labo Telecom shop (Building 31, Room S026) is able to make the standard sales, repairs and exchanges for authorised persons with a CERN subscription. Labo Telecom will thus become a specialist shop, open from 11 a.m. to 12 a.m., and will apply the usual rules and authorisation procedures of the stores. The paper form for requests for GSM subscriptions is being computerized and will be available on EDH in the near future.

  15. Calculus detection technologies: where do we stand now?

    Science.gov (United States)

    Archana, V

    2014-01-01

    Epidemiological studies have implicated dental calculus as an ideal substrate for subgingival microbial colonization. Therefore, the main objective of periodontal therapy is to eliminate the microbial biofilm along with the calculus deposits from the root surface by root surface debridement. Over the past years, a large number of clinical and laboratory studies have been conducted to evaluate the efficacy of calculus removal by various methods. None of these conventional methods or devices was effective in completely eliminating all the calculus from the diseased root surfaces. In this context, a number of newer technologies have been developed to identify and selectively remove the dental calculus. Regarding this fact, the present article highlights a critical review of these devices based on published clinical and experimental data.

  16. Literatura czeska i nowe media: wprowadzenie do tematu

    Czech Academy of Sciences Publication Activity Database

    Piorecký, Karel

    2015-01-01

    Roč. 16, č. 30 (2015), s. 63-88 ISSN 1508-6305 R&D Projects: GA ČR GPP406/12/P603 Institutional support: RVO:68378068 Keywords : Czech literature * literary culture * internet * new media * remediation Subject RIV: AJ - Letters, Mass- media , Audiovision

  17. Primary Production in the Delta: Then and Now

    Directory of Open Access Journals (Sweden)

    James E. Cloern

    2016-10-01

    Full Text Available doi: http://dx.doi.org/10.15447/sfews.2016v14iss3art1To evaluate the role of restoration in the recovery of the Delta ecosystem, we need to have clear targets and performance measures that directly assess ecosystem function. Primary production is a crucial ecosystem process, which directly limits the quality and quantity of food available for secondary consumers such as invertebrates and fish. The Delta has a low rate of primary production, but it is unclear whether this was always the case. Recent analyses from the Historical Ecology Team and Delta Landscapes Project provide quantitative comparisons of the areal extent of 14 habitat types in the modern Delta versus the historical Delta (pre-1850. Here we describe an approach for using these metrics of land use change to: (1 produce the first quantitative estimates of how Delta primary production and the relative contributions from five different producer groups have been altered by large-scale drainage and conversion to agriculture; (2 convert these production estimates into a common currency so the contributions of each producer group reflect their food quality and efficiency of transfer to consumers; and (3 use simple models to discover how tidal exchange between marshes and open water influences primary production and its consumption. Application of this approach could inform Delta management in two ways. First, it would provide a quantitative estimate of how large-scale conversion to agriculture has altered the Delta's capacity to produce food for native biota. Second, it would provide restoration practitioners with a new approach—based on ecosystem function—to evaluate the success of restoration projects and gauge the trajectory of ecological recovery in the Delta region.

  18. Exercise-induced pulmonary hemorrhage: where are we now?

    Directory of Open Access Journals (Sweden)

    Poole DC

    2016-11-01

    Full Text Available David C Poole,1,2 Howard H Erickson1 1Department of Anatomy and Physiology, 2Department of Kinesiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA Abstract: As the Thoroughbreds race for the final stretch, 44 hooves flash and thunder creating a cacophony of tortured air and turf. Orchestrated by selective breeding for physiology and biomechanics, expressed as speed, the millennia-old symphony of man and beast reaches its climax. At nearly 73 kilometers per hour (45 mph over half a ton of flesh and bone dwarfs its limpet-like jockey as, eyes wild and nostrils flaring, their necks stretch for glory. Beneath each resplendent livery-adorned, latherin-splattered coat hides a monstrous heart trilling at 4 beats per second, and each minute, driving over 400 L (105 gallons of oxygen-rich blood from lungs to muscles. Matching breath to stride frequency, those lungs will inhale 16 L (4 gallons of air each stride moving >1,000 L/min in and out of each nostril – and yet failing. Engorged with blood and stretched to breaking point, those lungs can no longer redden the arterial blood but leave it dusky and cyanotic. Their exquisitely thin blood–gas barrier, a mere 10.5 μm thick (1/50,000 of an inch, ruptures, and red cells invade the lungs. After the race is won and lost, long after the frenetic crowd has quieted and gone, that blood will clog and inflame the airways. For a few horses, those who bleed extensively, it will overflow their lungs and spray from their nostrils incarnadining the walls of their stall: a horrifically poignant canvas that strikes at horse racing’s very core. That exercise-induced pulmonary hemorrhage (EIPH occurs is a medical and physiological reality. That every reasonable exigency is not taken to reduce/prevent it would be a travesty. This review is not intended to provide an exhaustive coverage of EIPH for which the reader is referred to recent reviews, rather, after a brief reminder of its physiologic and pathologic bases, focus is brought on the latest developments in EIPH discovery as this informs state-of-the-art knowledge, the implementation of that knowledge and recommendations for future research and treatment. Keywords: epistaxis, Thoroughbred racehorse, pulmonary capillary rupture, vascular pressure, alveolar pressure, nasal airway collapse

  19. Extraterrestrial Life: Life on Mars - Then and Now

    Science.gov (United States)

    Arrhenius, Gustaf; Mojzsis, Stephen

    1996-01-01

    The recent claim to have identified possible signs of ancient life on Mars has been widely publicized and discussed. The authors conceded that none of the half-dozen pieces of evidence adduced in their paper individually provided strong support for extraterrestrial life, though they argued that the pieces added up to a case worth considering. Most - perhaps all - of the observed phenomena have counterparts in the inorganic world, so even the combination does not make a compelling case that there was ever life on Mars. Nevertheless, the importance of the problem has justified bringing the results to general attention. The paper has focussed interest on the origin and possible ubiquity of life, and on how we can design techniques capable of giving a more definitive answer to the question of whether there is, or has ever been, life elsewhere in the Universe.

  20. The European energy community, it is for now

    International Nuclear Information System (INIS)

    Andoura, S.; Buzek, J.; Delors, J.; Vitorino, A.

    2013-01-01

    Given that the European Council (on 22. May) mentioned the stakes involved for a common European energy policy, and that France's president has juts made another call to set up a European energy community, it is time to properly identify the main challenges that have to be met for such a project. The energy transition, that requires a deep change in our ways of producing, transporting and using energy, could be the basis of this new common policy. This new policy may follow 3 axis: first achieving the integration of a common energy market that will simulate the competitiveness of the European energy operators, secondly the security of supply implies a diversification of energy sources that could be reached through a stronger European solidarity, and thirdly a better cooperation between states for coordinating the construction of new infrastructures

  1. Workplace-based assessment in radiology-where to now?

    Energy Technology Data Exchange (ETDEWEB)

    Augustine, K. [Department of Radiology, Southmead Hospital, North Bristol NHS Trust, Bristol BS10 5NB (United Kingdom); McCoubrie, P., E-mail: paul.mccoubrie@nbt.nhs.u [Department of Radiology, Southmead Hospital, North Bristol NHS Trust, Bristol BS10 5NB (United Kingdom); Wilkinson, J.R. [Department of Cardiology, St Bartholomew' s Hospital, London (United Kingdom); McKnight, L. [Department of Radiology, Morriston Hospital, Swansea (United Kingdom)

    2010-04-15

    Assessment of doctors is in a state of flux. Traditional methods of assessment have been critically examined and found inherently limited. The wholesale shift towards outcome-orientated education in the last 10 years has led to the relatively rapid development of a radically different method of assessment. This method focuses on assessing what doctors do in everyday practice rather than written or practical simulations. Known collectively as 'workplace-based assessment' tools, these have been embraced in North America, whereas they have been more cautiously adopted in the UK. However, many of these assessment tools have not been rigorously studied and, moreover, few have been specifically developed for assessing radiologists. However, they are likely to be incorporated into radiology training in the near future. This paper critically analyses both the underpinning assumptions behind this method and the evidence behind existing tools, and looks at the work that is required to develop, adopt or adapt such tools for use in radiology.

  2. Porn Alley: Now at Your Local Public Library.

    Science.gov (United States)

    Schuyler, Michael

    1999-01-01

    Suggests that a definitive court ruling is needed to better define rights and responsibilities related to the First Amendment and libraries' Internet use policies so that libraries can provide a comfortable environment for users while maintaining the law. Discusses filters; court cases; claims of the anti-porn cult; research studies on how much of…

  3. Caffeine and the kidney: what evidence right now?

    Science.gov (United States)

    Bolignano, Davide; Coppolino, Giuseppe; Barillà, Antonio; Campo, Susanna; Criseo, Manila; Tripodo, Donatella; Buemi, Michele

    2007-07-01

    Caffeine, or 1, 3, 7-trimethylxanthine, is one of the most frequently consumed active drugs worldwide. Its main mechanisms of action include inhibiting the phosphodiesteratic enzyme and adenosine receptors and activating the ryanodine receptors with several actions on all organs. What effect does caffeine have on the kidney? Is caffeine beneficial or dangerous? A review of the current literature reveals conflicting opinions regarding the prolithiasic effect of this substance, whereas its diuretic action is least disputed and more easily observed. Caffeine may have a toxic or preventive effect in some physiologic or pathologic conditions. Some of these incongruences may depend on several factors, such as dosage, prior chronic exposure, genetic-enzymatic axes, and concomitant drug consumption. While awaiting further insight from forthcoming studies on the issue, we may reach a preliminary conclusion that, as yet, there is no evidence contraindicating the consumption of the equivalent of 3 to 4 cups of coffee per day in healthy or nephropathic subjects. However, particular attention should be paid to the elderly, children, and patients on concomitant treatment with analgesics or diuretics, whereas in subjects with a family or clinical history of calcium lithiasis a moderate caffeine consumption should be associated with an adequate fluid intake. Further in-depth studies are required to investigate whether this beverage is beneficial to patients on hemodialysis.

  4. Calculus detection technologies: where do we stand now?

    Science.gov (United States)

    Archana, V

    2014-01-01

    Epidemiological studies have implicated dental calculus as an ideal substrate for subgingival microbial colonization. Therefore, the main objective of periodontal therapy is to eliminate the microbial biofilm along with the calculus deposits from the root surface by root surface debridement. Over the past years, a large number of clinical and laboratory studies have been conducted to evaluate the efficacy of calculus removal by various methods. None of these conventional methods or devices was effective in completely eliminating all the calculus from the diseased root surfaces. In this context, a number of newer technologies have been developed to identify and selectively remove the dental calculus. Regarding this fact, the present article highlights a critical review of these devices based on published clinical and experimental data. PMID:25870667

  5. Outdoor air pollution and lung cancer: what now?

    Directory of Open Access Journals (Sweden)

    Enrico Pira

    2013-12-01

    Full Text Available In the last decade a substantial number of epidemiological studies suggested that outdoor air pollution and in particular respirable particulate matter (PM10 and fine particulate matter (PM2.5 are associated with an increased risk of lung cancer.The most recent is a multicentre European study...

  6. U.S.-Vietnam Relations: Is Now the Time?

    National Research Council Canada - National Science Library

    Medeiros, John

    1990-01-01

    .... Planning for restoration of relations has ebbed and flowed in the intervening 15 years, coming closest to realization in 1977-78 under the Carter Administration, which entered office intending...

  7. U.S. Geological Survey flies high for now

    Science.gov (United States)

    Clinton is asking Congress to keep the U.S. Geological Survey (USGS) alive and well in FY 1996. With a proposed 2.6% increase to $586 million, the Clinton request flies in the face of the Republican Contract with America that calls for abolishing the survey.Indeed, Clinton has made it clear that the onus will be on Congress if it wants to make major cuts at USGS. As Secretary of the Interior Bruce Babbitt puts it: “Good science is essential to good management.”

  8. Positron emission tomography now and in the future

    International Nuclear Information System (INIS)

    Vaalburg, W.

    1987-01-01

    A survey is given of positron emission tomography used in nuclear medicine. The production of positron emitting radionuclides is discussed. The development of positron detectors is described. The application of positron emission tomography in cardiology, oncology and neurology is treated. The authors conclude that PET is a unique method to examine metabolic processes, although the method is still in its infancy. 7 refs.; 1 table

  9. The Time Is Now: Bioethics and LGBT Issues.

    Science.gov (United States)

    Powell, Tia; Foglia, Mary Beth

    2014-09-01

    Our goal in producing this special issue is to encourage our colleagues to incorporate topics related to LGBT populations into bioethics curricula and scholarship. Bioethics has only rarely examined the ways in which law and medicine have defined, regulated, and often oppressed sexual minorities. This is an error on the part of bioethics. Medicine and law have served in the past as society's enforcement arm toward sexual minorities, in ways that robbed many people of their dignity. We feel that bioethics has an obligation to discuss that history and to help us as a society take responsibility for it. We can address only a small number of topics in this special issue of the Hastings Center Report, and we selected topics we believe will stimulate discourse. Andrew Solomon offers an elegant overview of the challenges that bioethics faces in articulating a solid basis for LGBT rights. Timothy F. Murphy asks whether bioethics still faces issues related to lesbian, gay, and bisexual people, given the deletion of homosexuality as a disease and the progress toward same-sex marriage. Jamie Lindemann Nelson's essay addresses the search for identity for transgender persons and the role of science in that search. Two articles, those by Brendan S. Abel and by Jack Drescher and Jack Pula, take up the complex issue of medical treatment for children who reject their assigned birth gender. Celia B. Fisher and Brian Mustanski address the special challenges of engaging LGBT youth in research, balancing the need for better information about this vulnerable group against the existing restrictions on research involving children. Tia Powell and Edward Stein consider the merits of legal bans on psychotherapies intended to change sexual orientation, particularly in the light of current research on orientation. Mary Beth Foglia and Karen I. Fredricksen-Goldsen highlight health disparities and resilience among LGBT older adults and then discuss the role of nonconscious bias in perpetuating disparities. Stephan Davis and Nancy Berlinger assess the challenges of access to care and health policy for transgender persons. Edward J. Callahan et al. tackle the ways in which diverse aspects of medicine should change to better incorporate the needs of LGBT patients, including through use of the electronic medical record, education of health professionals, and recruitment efforts for LGBT health professionals. Virginia Ashby Sharpe and Uchenna S. Uchendu describe multifaceted efforts within Veterans Administration facilities to create change for LGBT veterans across the largest integrated health care network in the United States. Lance Wahlert and Autumn Fiester find a mixed record in the use of case studies in teaching about LGBT issues. © 2014 by The Hastings Center.

  10. CERN car sharing scheme now open to everyone

    CERN Multimedia

    GS Department

    2011-01-01

    The CERN car sharing service is a self-service scheme providing a pool of 30 CERN cars available for pick-up free of charge from 13 points around the Meyrin and Prévessin sites. From Thursday, 1st December 2011, the service will be open to all members of the CERN personnel and contractors' personnel, in the framework of their professional activities at CERN only. The conditions of use can be consulted at: http://gs-dep.web.cern.ch/en/content/Mobility/Car_sharing To be able to use the service, members of the CERN personnel and contractors' personnel must: have a contractual link to CERN, possess an e-mail address registered in the CERN databases; hold an RFID access card, which can be obtained from the CERN Car Pool on presentation of a valid CERN access card. Car Pool, Building 130-R-012, open Monday-Friday, 8.00 a.m.-12.00 noon/1.00 p.m.-5.00 p.m. https://gs-dep.web.cern.ch/en/content/car-pool GS-IS

  11. Now, What? Standing in One's Generation, Taking Consultation

    Science.gov (United States)

    Charles, Marilyn

    2016-01-01

    I situate myself in the context of an evolving conversation in relation to what it means to be a woman. In my mother's generation, the first wave of feminism forced a collision between traditional western female values grounded in a subversive authority and the desire to emerge from that type of repressive position. From the standpoint of my…

  12. Changing World, Changing Education: Kindergarten--Where to Now?

    Science.gov (United States)

    Clyde, Margaret

    This paper discusses the history of early childhood education in Australia, areas of change in contemporary early childhood education, and the philosophical bases of education. The paper also offers suggestions for the future. From 1880 until 1950, Australian children's services consisted of philanthropic enterprises. The period from 1950 to 1970…

  13. Ten--Now--Next: A Postmodern Peek at Everything.

    Science.gov (United States)

    Hodgkinson, Christopher

    2000-01-01

    The values of the short-term future are implicit: an unholy Apollonian-Dionysian mix of rationalistic, legalistic, bureaucratic, scientific pragmatics, and a reactive, postmodern, relativistic, hedonistic, narcissistic, materialistic nihilism. For education, this might imply a skew toward the digital, the mathematical, the marketable, and the…

  14. Primary production in the Delta: Then and now

    Science.gov (United States)

    Cloern, James E.; Robinson, April; Richey, Amy; Grenier, Letitia; Grossinger, Robin; Boyer, Katharyn E.; Burau, Jon; Canuel, Elizabeth A.; DeGeorge, John F.; Drexler, Judith Z.; Enright, Chris; Howe, Emily R.; Kneib, Ronald; Mueller-Solger, Anke; Naiman, Robert J.; Pinckney, James L.; Safran, Samuel M.; Schoellhamer, David H.; Simenstad, Charles A.

    2016-01-01

    To evaluate the role of restoration in the recovery of the Delta ecosystem, we need to have clear targets and performance measures that directly assess ecosystem function. Primary production is a crucial ecosystem process, which directly limits the quality and quantity of food available for secondary consumers such as invertebrates and fish. The Delta has a low rate of primary production, but it is unclear whether this was always the case. Recent analyses from the Historical Ecology Team and Delta Landscapes Project provide quantitative comparisons of the areal extent of 14 habitat types in the modern Delta versus the historical Delta (pre-1850). Here we describe an approach for using these metrics of land use change to: (1) produce the first quantitative estimates of how Delta primary production and the relative contributions from five different producer groups have been altered by large-scale drainage and conversion to agriculture; (2) convert these production estimates into a common currency so the contributions of each producer group reflect their food quality and efficiency of transfer to consumers; and (3) use simple models to discover how tidal exchange between marshes and open water influences primary production and its consumption. Application of this approach could inform Delta management in two ways. First, it would provide a quantitative estimate of how large-scale conversion to agriculture has altered the Delta's capacity to produce food for native biota. Second, it would provide restoration practitioners with a new approach—based on ecosystem function—to evaluate the success of restoration projects and gauge the trajectory of ecological recovery in the Delta region.

  15. The Masters of Economics: Where Are We Now?

    Science.gov (United States)

    McCoy, James P.; Milkman, Martin I.; Marjadi, Riza

    2014-01-01

    In this article, the authors present results from a survey of Masters of Economics program directors to determine the missions, inputs, and outcomes of these degree programs throughout the United States and Canada. They compare results of this survey to those of two previous studies that they conducted 20 and 10 years ago. Respondents were asked…

  16. Future value now. Cashing sustainability in area development

    International Nuclear Information System (INIS)

    Huismans, G.; De Vaan, M.

    2011-06-01

    Several actors have an interest in the added value of a high quality of area development - and they also want to invest. In more and more places new strategies are developed to realize sustainable areas. Inspiring examples show that even within the present context much is possible. In many places in the Netherlands, targets in terms of energy, water, waste and green are operationalized and embedded in the financial business cases for area developments. [nl

  17. The Devran Petroleum story: Nice idea, now what?

    International Nuclear Information System (INIS)

    Cowan, J.F.

    1993-01-01

    The history of the Devran petroleum company is reviewed. The company began in Ontario in 1982 and its first venture, a 50% partnership with Shell Canada, was to excavate two drilling rooms 430 ft into the depleted Sarnia-London (Ontario) oil field and drill 11 horizontal wells to obtain oil production. This venture produced very little crude and was abandoned due to excessive water inflow. Devran's next initiative was to purchase the Ontario government's share in Onexco Oil and Gas, which had a number of Ontario properties and eight wells. The high netbacks per bbl characteristic of Ontario reservoirs enabled Devran to survive and pay off loans for the Onexco purchase, and the number of Devran's Ontario wells rose to over 50. Devran then acquired a Toronto Stock Exchange listing and bought a 23% interest in the Pelican Lake horizontal drilling project in western Canada. This project was successful and is still continuing at a maximum production rate of 2,000 bbl/d. The company then bought into other successful partnerships in Saskatchewan and began a gas exploration project in Western Alberta with NuGas Ltd. as the operator. Devran's total oil production is currently ca 1,400 bbl/d and netbacks are ca $10.40/bbl, higher than the industry average of $8.82/bbl. Its market capital is ca $30 million and it trades at a market price equal to net asset value

  18. IRIS COLOUR CLASSIFICATION SCALES – THEN AND NOW

    Science.gov (United States)

    Grigore, Mariana; Avram, Alina

    2015-01-01

    Eye colour is one of the most obvious phenotypic traits of an individual. Since the first documented classification scale developed in 1843, there have been numerous attempts to classify the iris colour. In the past centuries, iris colour classification scales has had various colour categories and mostly relied on comparison of an individual’s eye with painted glass eyes. Once photography techniques were refined, standard iris photographs replaced painted eyes, but this did not solve the problem of painted/ printed colour variability in time. Early clinical scales were easy to use, but lacked objectivity and were not standardised or statistically tested for reproducibility. The era of automated iris colour classification systems came with the technological development. Spectrophotometry, digital analysis of high-resolution iris images, hyper spectral analysis of the human real iris and the dedicated iris colour analysis software, all accomplished an objective, accurate iris colour classification, but are quite expensive and limited in use to research environment. Iris colour classification systems evolved continuously due to their use in a wide range of studies, especially in the fields of anthropology, epidemiology and genetics. Despite the wide range of the existing scales, up until present there has been no generally accepted iris colour classification scale. PMID:27373112

  19. Predicting outcome in melanoma: where are we now?

    LENUS (Irish Health Repository)

    Jennings, L

    2009-09-01

    Melanoma incidence continues to rise in most countries. This is of grave concern, given the mortality rate in a relatively young population. Current staging tools are limited in their ability to predict accurately those at risk of metastatic disease, relapse and treatment failure. This overview comprehensively reviews relevant literature, with the focus on the last 5 years, and discusses the current state of traditional and emerging novel methods of staging for melanoma and their effect on prognosis in this population.

  20. Can you hear me now? Teaching listening skills.

    Science.gov (United States)

    Nemec, Patricia B; Spagnolo, Amy Cottone; Soydan, Anne Sullivan

    2017-12-01

    This column provides an overview of methods for training to improve service provider active listening and reflective responding skills. Basic skills in active listening and reflective responding allow service providers to gather information about and explore the needs, desires, concerns, and preference of people using their services-activities that are of critical importance if services are to be truly person-centered and person-driven. Sources include the personal experience of the authors as well as published literature on the value of basic counseling skills and best practices in training on listening and other related soft skills. Training in listening is often needed but rarely sought by behavioral health service providers. Effective curricula exist, providing content and practice opportunities that can be incorporated into training, supervision, and team meetings. When providers do not listen well to the people who use their services, the entire premise of recovery-oriented person-driven services is undermined. (PsycINFO Database Record (c) 2017 APA, all rights reserved).