Reduced survival for uncemented compared to cemented total hip arthroplasty after operatively treated acetabular fractures.

Science.gov (United States)

Clarke-Jenssen, John; Westberg, Marianne; Røise, Olav; Storeggen, Stein Arne Øvre; Bere, Tone; Silberg, Ingunn; Madsen, Jan Erik

2017-11-01

Post traumatic arthritis and avascular necrosis of the femoral head are common complications after operatively treated acetabular fractures. This may cause severe disabilities for the patient, necessitating a total hip arthroplasty. Even though an arthroplasty may provide good symptomatic relief, the long-term results are more uncertain and no consensus exists according to preferred prosthetic designs. With this cohort study, we aimed to investigate the medium to long term arthroplasty survival and clinical results of total hip arthroplasty after operatively treated acetabular fractures. We included 52 patients treated with a secondary total hip arthroplasty at a median of 2.4 (0.1-14.1) years after an operatively treated acetabular fracture. The median age was 54 (11-82) years. Cemented arthroplasty was used for 33 patients, 10 patients had an uncemented arthroplasty and 9 patients received a hybrid arthroplasty. Average follow up was 8.0 (SD 5.0) years. Ten-year revision free arthroplasty survival was 79%. Uncemented arthroplasties had a significantly worse 10-year survival of 57%. Arthroplasties performed at a centre without a pelvic fracture service also had a significantly worse 10-years survival of 51%. Cox regression showed similar results with an 8-fold increase in risk of revision for both uncemented arthroplasties and operations performed at a non-pelvic trauma centre. Total hip arthroplasty secondary to an operatively treated acetabular fracture provides good symptomatic relief. These patients are, however, complex cases and are probably best treated at specialist centres with both pelvic trauma surgeons and arthroplasty surgeons proficient in complex revisions present. Copyright © 2017 Elsevier Ltd. All rights reserved.

PSLn(q) as operator group of isospectral drums

International Nuclear Information System (INIS)

Thas, Koen

2006-01-01

In a paper by M Kac (1966 Am. Math. Mon. 73 1-23), Kac asked his famous question 'Can one hear the shape of a drum?', which was answered negatively in Gordon et al (1992 Invent. Math. 110 1-22) by construction of planar isospectral pairs. In Buser et al (1994 Int. Math. Res. Not. 9), it is observed that all operator groups associated with the known counter examples are isomorphic to one of PSL 3 (2), PSL 3 (3), PSL 4 (2) and PSL 3 (4). We show that if (D 1 , D 2 ) is a pair of non-congruent planar isospectral domains constructed from unfolding a polygonal base-tile and with associated operator group PSL n (q), then (n, q) belongs to this very restricted list. (letter to the editor)

Coaching Non-technical Skills Improves Surgical Residents' Performance in a Simulated Operating Room.

Science.gov (United States)

Yule, Steven; Parker, Sarah Henrickson; Wilkinson, Jill; McKinley, Aileen; MacDonald, Jamie; Neill, Adrian; McAdam, Tim

2015-01-01

To investigate the effect of coaching on non-technical skills and performance during laparoscopic cholecystectomy in a simulated operating room (OR). Non-technical skills (situation awareness, decision making, teamwork, and leadership) underpin technical ability and are critical to the success of operations and the safety of patients in the OR. The rate of developing assessment tools in this area has outpaced development of workable interventions to improve non-technical skills in surgical training and beyond. A randomized trial was conducted with senior surgical residents (n = 16). Participants were randomized to receive either non-technical skills coaching (intervention) or to self-reflect (control) after each of 5 simulated operations. Coaching was based on the Non-Technical Skills For Surgeons (NOTSS) behavior observation system. Surgeon-coaches trained in this method coached participants in the intervention group for 10 minutes after each simulation. Primary outcome measure was non-technical skills, assessed from video by a surgeon using the NOTSS system. Secondary outcomes were time to call for help during bleeding, operative time, and path length of laparoscopic instruments. Non-technical skills improved in the intervention group from scenario 1 to scenario 5 compared with those in the control group (p = 0.04). The intervention group was faster to call for help when faced with unstoppable bleeding in the final scenario (no. 5; p = 0.03). Coaching improved residents' non-technical skills in the simulated OR compared with those in the control group. Important next steps are to implement non-technical skills coaching in the real OR and assess effect on clinically important process measures and patient outcomes. Copyright © 2015 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

Post-operative analgesic requirement in non-closure and closure of peritoneum during open appendectomy

International Nuclear Information System (INIS)

Khan, A.W.; Maqsood, R.; Saleem, M.M.

2017-01-01

To compare the mean post-operative analgesic requirement in non-closure and closure of peritoneum during open appendectomy. Study Design: Randomized controlled trial. Place and Duration of Study: Department of General Surgery Combined Military Hospital Quetta, from 1st August 2014 to 30th April 2015. Material and Methods: A total of 60 patients were included in this study and were divided into two groups of 30 each. Patients in group A underwent open appendectomy with closure of peritoneum while patients in group B had non-closure of peritoneum during the same procedure. Post-operatively, pain severity was assessed on visual analogue scale (VAS) numeric pain distress scale. On presence of VAS numeric pain distress scale between 5 to 7, intramuscular (IM) diclofenac sodium was given and on score >7, intravascular (IV) tramadol was given. The final outcome was measured at day 0 and day 1. Results: Pain score and analgesic requirements were significantly less in non-closure group than closure group on day 0 and day 1, showing statistically significant difference between the two groups. Conclusion: Mean post-operative analgesic requirement is significantly less in non-closure group as compared to closure group during open appendectomy. (author)

The emerging trend of non-operative treatment in paediatric type I open forearm fractures.

Science.gov (United States)

Zhang, H; Fanelli, M; Adams, C; Graham, J; Seeley, M

2017-08-01

Open fractures are considered an orthopaedic emergency and are generally an indication for operative debridement. Recent studies have questioned this approach for the management of Gustilo-Anderson Type I open fractures in the paediatric population. This meta-analysis studies the non-operative management of Type I open paediatric forearm fractures. An Ovid MEDLINE and PubMed database literature search was performed for studies that involved a quantified number of Gustilo-Anderson Type I open forearm fractures in the paediatric population, which were treated without operative intervention. A fixed-effect meta-analysis, weighting each study based on the number of patients, and a pooled estimate of infection risk (with 95% confidence interval (CI)) was performed. The search results yielded five studies that were eligible for inclusion. No included patients had operative debridement and all were treated with antibiotics. The number of patients in each study ranged from 3 to 45, with a total of 127 paediatric patients in the meta-analysis. The infection rate was 0% for all patients included. The meta-analysis estimated a pooled infection risk of 0% (95% CI 0 to 2.9). The five included studies had a total of 127 patients with no cases of infection after non-operative management of Type I open paediatric forearm fractures. The infection rate of Type I fractures among operatively managed patients is 1.9%. The trend in literature towards non-operative treatment of paediatric Type I open fractures holds true in this meta-analysis.

[Post-operative analgesia in case of ano-rectal diseases].

Science.gov (United States)

Rossitto, Maurizio; Pantè, Sebastiano; Manfrè, Antonino; Ciccolo, Antonio

2009-01-01

The aim of the study was that to evaluate the post-operative pain in case of ano-rectal diseases wether treated by ketorolac, or buprenorphine or tramadol. The intensity of post-operative pain was evaluated in 60 patients with hemorrhoidal diseases, fistulae, abscesses and anal neoplasms, divided into three homogenous groups and treated with intramuscular ketorolac (Group I), transdermal buprenorphine (Group II) and tramadol in elastomeric pump (Group III). The average index of the visual analogue scale, as mean to evaluate the intensity of the post-operative pain, was 1,85 in the first group, 1,20 in the second one and 1,40 in the third group. In patients treated with transdermal buprenorphine or with tramadol in elastomeric pump there has been a more quick psycho-physical recovery than in those treated with ketorolac; the management of elastomeric pump represents however for patients cause of concern while the transdermal system is a kind of rational and comfortable way of treatment of the pain, with the advantage of being non-invasive. Better compliance and lower operating costs have given the preference to the use of transdermal buprenorphine for the treatment of diseases of the post-operative pain in the diseases of the anal canal.

Interagency mechanical operations group numerical systems group

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-09-01

This report consists of the minutes of the May 20-21, 1971 meeting of the Interagency Mechanical Operations Group (IMOG) Numerical Systems Group. This group looks at issues related to numerical control in the machining industry. Items discussed related to the use of CAD and CAM, EIA standards, data links, and numerical control.

The outcome of treating ESBL infections with carbapenems vs. non carbapenem antimicrobials.

Science.gov (United States)

Trivedi, Mayuri; Trivedi, Mayur; Patel, Vipul; Soman, Rajeev; Rodriguez, Camilla; Singhal, Tanu

2012-08-01

In India where the prevalence of extended spectrum beta lactamase (ESBL) producing organisms among gram negative organisms is 60-70% and Ertapenem was unavailable at the beginning of this study, exclusive use of Group 2 Carbapenems (Imipenem and Meropenem) for treatment raises issues of cost and development of resistance. Therefore the role of non-Carbapenem alternatives, chiefly Betalactam + Betalactamase inhibitors (BL-BLI) was explored in this prospective observational study at a private tertiary care teaching hospital. 522 consecutive in door patients from the period between June 2006 to March 2007and June 2008 to December 2008, who had true infections with ESBL producing organisms were enrolled in the study. Antimicrobials were prescribed or changed by the treating physicians on the basis of the nature and severity of infection, the susceptibility of the organism and the affordability of the patient. Patients who received a Carbapenem at any time during treatment were considered in the Carbapenem group. Those who never received a Carbapenem at any time during treatment were considered in the non-Carbapenem group. Of the 522 infections, 287 were urinary tract infections, 60 were skin structure infections, 60 were bacteremias, 55 were hospital acquired pneumonias, 31 were intra-abdominal infections and 29 were other infections. There were 351 E. coli, 119 K. pneumoniae, 23 K. oxytoca, 16 Enterobacter aerogenes, 5 Kozoanae, 4 Enterobacter agglomerans, 3 Citrobacter freundi, 1 E. cloacae, 1 Enterobacterspp. and 1 Morgenella morganii isolates. Clinical outcomes were available for 486 patients. 339 patients who were in the non-Carbapenem group and who might have had less serious infections had a clinical success rate of 79.6%. 147 patients who were in the Carbapenem group and who might have had more serious infections had a clinical success rate of 85.71%. It is possible to successfully treat at least the less serious infections due to ESBL producing gram negative

200 Area treated effluent disposal facility operational test report

International Nuclear Information System (INIS)

Crane, A.F.

1995-01-01

This document reports the results of the 200 Area Treated Effluent Disposal Facility (200 Area TEDF) operational testing activities. These completed operational testing activities demonstrated the functional, operational and design requirements of the 200 Area TEDF have been met

Claims of operators, non-operators and third parties arising from oil and gas operations

International Nuclear Information System (INIS)

Block, R.W.; Semadeni, T.

1999-01-01

There has come a resurgence in the number of companies involved in the oil and gas industry seeking protection from their creditors because of the recent weakness in commodity prices. Because most operations in this industry are conducted jointly, a single insolvency can lead to a toppling of other participants in the joint venture and beyond. The problem is to minimize one's losses if other members of the joint venture become insolvent. An examination is included of some remedies which may be available to operators, non-operators and third parties when faced with an insolvent oil and gas participant. The remedies which may be available to the non-operator that is owed moneys by its operator are discussed. The remedies that the operator has against its non-operators, with an emphasis on the nature of the operator's lien and the right of set-off, are described. A brief review is included of some of the remedies that might be available to a third party as against the operators and non-operators. Some s uggestions are included for directors, bankers, third parties, non-operators and operators

Assessing Nurse Anaesthetists' Non-Technical Skills in the operating room.

Science.gov (United States)

Lyk-Jensen, H T; Jepsen, R M H G; Spanager, L; Dieckmann, P; Østergaard, D

2014-08-01

Incident reporting and fieldwork in operating rooms have shown that some of the errors that arise in anaesthesia relate to inadequate use of non-technical skills. To provide a tool for training and feedback on nurse anaesthetists' non-technical skills, this study aimed to adapt the Anaesthetists' Non-Technical Skills (ANTS) as a behavioural marker system for the formative assessment of nurse anaesthetists' non-technical skills in the operating room. A qualitative approach with focus group interviews was used to identify the non-technical skills of nurse anaesthetists in the operating room. The interview data were transcribed verbatim. Directed content analysis was used to code and sort data deductively into the ANTS categories: task management, team working, situation awareness and decision making. The prototype named Nurse Anaesthetists' Non-Technical Skills (N-ANTS) was presented and discussed in a group of subject matter experts to ensure face validity. The N-ANTS system consists of the same four categories as ANTS and 15 underlying elements. Three to five good and poor behavioural markers for each element were identified. The headings and definitions of the categories and elements were adjusted to encompass the behavioural markers in N-ANTS. The differences that emerged mainly reflected statements regarding the establishment of role, competence, and task delegation. A behavioural marker system, N-ANTS, for nurse anaesthetists was adapted from a behavioural marker system, ANTS, for anaesthesiologists. © 2014 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

Vertex operators, non-abelian orbifolds and the Riemann-Hilbert problem

International Nuclear Information System (INIS)

Gato, B.; Massachusetts Inst. of Tech., Cambridge

1990-01-01

We show how to construct the oscillator part of vertex operators for the bosonic string moving on non-abelian orbifolds, using the conserved charges method. When the three-string vertices are twisted by non-commuting group elements, the construction of the conserved charges becomes the Riemann-Hilbert problem with monodromy matrices given by the twists. This is solvable for any given configuration and any non-abelian orbifold. (orig.)

Prognostic factors in non-surgically treated sciatica: a systematic review.

Science.gov (United States)

Ashworth, Julie; Konstantinou, Kika; Dunn, Kate M

2011-09-25

When present sciatica is considered an obstacle to recovery in low back pain patients, yet evidence is limited regarding prognostic factors for persistent disability in this patient group. The aim of this study is to describe and summarise the evidence regarding prognostic factors for sciatica in non-surgically treated cohorts. Understanding the prognostic factors in sciatica and their relative importance may allow the identification of patients with particular risk factors who might benefit from early or specific types of treatment in order to optimise outcome. A systematic literature search was conducted using Medline, EMBASE and CINAHL electronic databases. Prospective cohort studies describing subjects with sciatica and measuring pain, disability or recovery outcomes were included. Studies of cohorts comprised entirely of surgically treated patients were excluded and mixed surgically and conservatively treated cohorts were included only if the results were analysed separately by treatment group or if the analysis was adjusted for treatment. Seven adequate or high quality eligible studies were identified. There were conflicting but mainly negative results regarding the influence of baseline pain severity, neurological deficit, nerve root tension signs, duration of symptoms and radiological findings on outcome. A number of factors including age, gender, smoking, previous history of sciatica and heaviness of work do not appear to influence outcome. In contrast to studies of low back pain and purely surgically treated sciatica cohorts, psychological factors were rarely investigated. At present, the heterogeneity of the available studies makes it difficult to draw firm conclusions about sciatica prognosis, and highlights the need for further research for this group of patients. Large scale prospective studies of high methodological quality, using a well-defined, consistent definition of sciatica and investigating psychosocial factors alongside clinical and

The role of non-operative management (NOM in blunt hepatic trauma

Directory of Open Access Journals (Sweden)

Ayman Zaki Azzam

2013-09-01

Full Text Available Background: NOM in blunt hepatic trauma is the preferred treatment in otherwise stable patients. Aim: To evaluate the role of NOM in blunt hepatic trauma, avoiding unnecessary surgery. Methods and patients: Forty-four patients who presented with blunt hepatic trauma were admitted to the Emergency Unit. The patients were evaluated clinically. Abdominal computerized tomography was done to all hemodynamically stable patients and who were stabilized by the initial resuscitation. Staging of liver injury was done according to the scoring of the American Association for the Surgery of Trauma (AAST. Initially, all patients were treated conservatively and the patients who needed laparotomy later were considered as failure of NOM. Liver injuries due to penetrating causes were excluded. An informed consent was taken from each patient. Results: Blunt trauma was the mechanism of injury in 44 patients (60.2% including road traffic accidents in 42.5%. The peak age was between 20 and 30 years. The male to female ratio was 10:1. The majority of patients have multiple injuries with 10% having isolated liver injury. Thirty-six patients (82% had one or more associated extra-abdominal injuries. Surgery was indicated in 14 patients (32%. The mean admission systolic pressure was lower in the NOM failure group (90 vs. 122 mmHg with p < 0.04. Complications occurred more in the operative group, chest infection occurred in 21.4% with a p value of 0.001, hyperpyrexia occurred in 21.4% with a p value of 0.001, and wound infection in 14.2% with a p value of 0.025. Mortality occurred in 7 patients. The cause of death in patients with blunt hepatic trauma was liver related in 2 patients due to hemorrhage and DIC. Conclusion: NOM in blunt hepatic trauma is the preferred treatment in otherwise stable patients. The factors that can suspect failure of NOM were the development of hemodynamic instability or the presence of associated injury that mandates immediate exploration

Operability of glioblastomas: "sins of action" versus "sins of non-action".

Science.gov (United States)

Ferroli, Paolo; Schiariti, Marco; Finocchiaro, Gaetano; Salmaggi, Andrea; Castiglione, Melina; Acerbi, Francesco; Tringali, Giovanni; Farinotti, Mariangela; Broggi, Morgan; Roberto, Cordella; Maccagnano, Elio; Broggi, Giovanni

2013-12-01

Despite prognosis of glioblastomas is still poor, mounting evidence suggests that more extensive surgical resections are associated with longer life expectancy. However, the surgical indications, at present, are far from uniform and the concept of operability is extremely surgeon-dependant. The results of glioblastoma resection in 104 patients operated on between March 2005 and April 2011 were reviewed with the aim to shed some light on the limits between 'sins of action' (operating upon complex tumors causing a permanent severe deficit) and 'sins of non-action' (considering inoperable tumors that can be resected with good results). Fifty-five patients (54.4 %) (Group 1) presented with a 'disputable' surgical indication because of one or more of the following clinico-radiological aspects: involvement of motor and language areas (39.4 %), deep location (7.7 %), corpus callosum infiltration (13.4 %), or major vessels encasement (8.6 %). Forty-six (42.5 %) patients (Group 2) presented with an 'indisputable' surgical indication (readily accessible tumors in non-eloquent areas). Overall mortality was 2.9 %. The mean overall survival was 19.8 months and not significantly different in the two Groups (20.4 Group 2 and 19.5 months for Group 1; p = 0.7). Patients with GTR and <72 years had a longer survival (p = 0.004 and 0.03, respectively). Seventy patients (69.3 %) showed an uneventful post-operative course, without statistical significance difference between Group 1 and 2. The gross total removal of glioblastoma with many complexities (Group 1) was found to be feasible with acceptable mortality, morbidity and long-term survival rates.

Non-commutative representation for quantum systems on Lie groups

Energy Technology Data Exchange (ETDEWEB)

Raasakka, Matti Tapio

2014-01-27

The topic of this thesis is a new representation for quantum systems on weakly exponential Lie groups in terms of a non-commutative algebra of functions, the associated non-commutative harmonic analysis, and some of its applications to specific physical systems. In the first part of the thesis, after a review of the necessary mathematical background, we introduce a {sup *}-algebra that is interpreted as the quantization of the canonical Poisson structure of the cotangent bundle over a Lie group. From the physics point of view, this represents the algebra of quantum observables of a physical system, whose configuration space is a Lie group. We then show that this quantum algebra can be represented either as operators acting on functions on the group, the usual group representation, or (under suitable conditions) as elements of a completion of the universal enveloping algebra of the Lie group, the algebra representation. We further apply the methods of deformation quantization to obtain a representation of the same algebra in terms of a non-commutative algebra of functions on a Euclidean space, which we call the non-commutative representation of the original quantum algebra. The non-commutative space that arises from the construction may be interpreted as the quantum momentum space of the physical system. We derive the transform between the group representation and the non-commutative representation that generalizes in a natural way the usual Fourier transform, and discuss key properties of this new non-commutative harmonic analysis. Finally, we exhibit the explicit forms of the non-commutative Fourier transform for three elementary Lie groups: R{sup d}, U(1) and SU(2). In the second part of the thesis, we consider application of the non-commutative representation and harmonic analysis to physics. First, we apply the formalism to quantum mechanics of a point particle on a Lie group. We define the dual non-commutative momentum representation, and derive the phase

Non-commutative representation for quantum systems on Lie groups

International Nuclear Information System (INIS)

Raasakka, Matti Tapio

2014-01-01

The topic of this thesis is a new representation for quantum systems on weakly exponential Lie groups in terms of a non-commutative algebra of functions, the associated non-commutative harmonic analysis, and some of its applications to specific physical systems. In the first part of the thesis, after a review of the necessary mathematical background, we introduce a * -algebra that is interpreted as the quantization of the canonical Poisson structure of the cotangent bundle over a Lie group. From the physics point of view, this represents the algebra of quantum observables of a physical system, whose configuration space is a Lie group. We then show that this quantum algebra can be represented either as operators acting on functions on the group, the usual group representation, or (under suitable conditions) as elements of a completion of the universal enveloping algebra of the Lie group, the algebra representation. We further apply the methods of deformation quantization to obtain a representation of the same algebra in terms of a non-commutative algebra of functions on a Euclidean space, which we call the non-commutative representation of the original quantum algebra. The non-commutative space that arises from the construction may be interpreted as the quantum momentum space of the physical system. We derive the transform between the group representation and the non-commutative representation that generalizes in a natural way the usual Fourier transform, and discuss key properties of this new non-commutative harmonic analysis. Finally, we exhibit the explicit forms of the non-commutative Fourier transform for three elementary Lie groups: R d , U(1) and SU(2). In the second part of the thesis, we consider application of the non-commutative representation and harmonic analysis to physics. First, we apply the formalism to quantum mechanics of a point particle on a Lie group. We define the dual non-commutative momentum representation, and derive the phase space path

Personalised Hip Therapy: development of a non-operative protocol to treat femoroacetabular impingement syndrome in the FASHIoN randomised controlled trial.

Science.gov (United States)

Wall, Peter Dh; Dickenson, Edward J; Robinson, David; Hughes, Ivor; Realpe, Alba; Hobson, Rachel; Griffin, Damian R; Foster, Nadine E

2016-10-01

Femoroacetabular impingement (FAI) syndrome is increasingly recognised as a cause of hip pain. As part of the design of a randomised controlled trial (RCT) of arthroscopic surgery for FAI syndrome, we developed a protocol for non-operative care and evaluated its feasibility. In phase one, we developed a protocol for non-operative care for FAI in the UK National Health Service (NHS), through a process of systematic review and consensus gathering. In phase two, the protocol was tested in an internal pilot RCT for protocol adherence and adverse events. The final protocol, called Personalised Hip Therapy (PHT), consists of four core components led by physiotherapists: detailed patient assessment, education and advice, help with pain relief and an exercise-based programme that is individualised, supervised and progressed over time. PHT is delivered over 12-26 weeks in 6-10 physiotherapist-patient contacts, supplemented by a home exercise programme. In the pilot RCT, 42 patients were recruited and 21 randomised to PHT. Review of treatment case report forms, completed by physiotherapists, showed that 13 patients (62%) received treatment that had closely followed the PHT protocol. 13 patients reported some muscle soreness at 6 weeks, but there were no serious adverse events. PHT provides a structure for the non-operative care of FAI and offers guidance to clinicians and researchers in an evolving area with limited evidence. PHT was deliverable within the National Health Service, is safe, and now forms the comparator to arthroscopic surgery in the UK FASHIoN trial (ISRCTN64081839). ISRCTN 09754699. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Spectral monodromy of non-self-adjoint operators

International Nuclear Information System (INIS)

Phan, Quang Sang

2014-01-01

In the present paper, we build a combinatorial invariant, called the “spectral monodromy” from the spectrum of a single (non-self-adjoint) h-pseudodifferential operator with two degrees of freedom in the semi-classical limit. Our inspiration comes from the quantum monodromy defined for the joint spectrum of an integrable system of n commuting self-adjoint h-pseudodifferential operators, given by S. Vu Ngoc [“Quantum monodromy in integrable systems,” Commun. Math. Phys. 203(2), 465–479 (1999)]. The first simple case that we treat in this work is a normal operator. In this case, the discrete spectrum can be identified with the joint spectrum of an integrable quantum system. The second more complex case we propose is a small perturbation of a self-adjoint operator with a classical integrability property. We show that the discrete spectrum (in a small band around the real axis) also has a combinatorial monodromy. The main difficulty in this case is that we do not know the description of the spectrum everywhere, but only in a Cantor type set. In addition, we also show that the corresponding monodromy can be identified with the classical monodromy, defined by J. Duistermaat [“On global action-angle coordinates,” Commun. Pure Appl. Math. 33(6), 687–706 (1980)

Spectral monodromy of non-self-adjoint operators

Science.gov (United States)

Phan, Quang Sang

2014-01-01

In the present paper, we build a combinatorial invariant, called the "spectral monodromy" from the spectrum of a single (non-self-adjoint) h-pseudodifferential operator with two degrees of freedom in the semi-classical limit. Our inspiration comes from the quantum monodromy defined for the joint spectrum of an integrable system of n commuting self-adjoint h-pseudodifferential operators, given by S. Vu Ngoc ["Quantum monodromy in integrable systems," Commun. Math. Phys. 203(2), 465-479 (1999)]. The first simple case that we treat in this work is a normal operator. In this case, the discrete spectrum can be identified with the joint spectrum of an integrable quantum system. The second more complex case we propose is a small perturbation of a self-adjoint operator with a classical integrability property. We show that the discrete spectrum (in a small band around the real axis) also has a combinatorial monodromy. The main difficulty in this case is that we do not know the description of the spectrum everywhere, but only in a Cantor type set. In addition, we also show that the corresponding monodromy can be identified with the classical monodromy, defined by J. Duistermaat ["On global action-angle coordinates," Commun. Pure Appl. Math. 33(6), 687-706 (1980)].

Spectral monodromy of non-self-adjoint operators

Energy Technology Data Exchange (ETDEWEB)

Phan, Quang Sang, E-mail: quang.phan@uj.edu.pl [Université de Rennes 1, Institut de Recherche Mathématique de Rennes (UMR 6625), Campus de Beaulieu, 35042 Rennes (France)

2014-01-15

In the present paper, we build a combinatorial invariant, called the “spectral monodromy” from the spectrum of a single (non-self-adjoint) h-pseudodifferential operator with two degrees of freedom in the semi-classical limit. Our inspiration comes from the quantum monodromy defined for the joint spectrum of an integrable system of n commuting self-adjoint h-pseudodifferential operators, given by S. Vu Ngoc [“Quantum monodromy in integrable systems,” Commun. Math. Phys. 203(2), 465–479 (1999)]. The first simple case that we treat in this work is a normal operator. In this case, the discrete spectrum can be identified with the joint spectrum of an integrable quantum system. The second more complex case we propose is a small perturbation of a self-adjoint operator with a classical integrability property. We show that the discrete spectrum (in a small band around the real axis) also has a combinatorial monodromy. The main difficulty in this case is that we do not know the description of the spectrum everywhere, but only in a Cantor type set. In addition, we also show that the corresponding monodromy can be identified with the classical monodromy, defined by J. Duistermaat [“On global action-angle coordinates,” Commun. Pure Appl. Math. 33(6), 687–706 (1980)].

Method of treating non-supporting underground formations

International Nuclear Information System (INIS)

Anderson, B.W.; Trotty, K.D.

1977-01-01

Method of treating non-supporting underground formations, through which passes a borehole, aimed at preventing the transport of sand particles from the formation into the borehole during conveyance of liquids. (orig./RW) [de

Ipsilateral Femoral Fracture Non-Union and Delayed Union Treated By Hybrid Plate Nail Fixation and Vascularized Fibula Bone Grafting: A Case Report

Directory of Open Access Journals (Sweden)

CK Chan

2013-07-01

Full Text Available Non-union is a well recognized complication of femoral neck fractures. The decision whether to attempt fracture fixation or to resort to hip replacement is particularly difficult in patients in the borderline age group in whom complex attempts at gaining union may fail and later present a difficult revision. On the other hand the patient may be young enough that arthroplasty best be avoided . Besides, presence of ipsilateral femoral shaft fracture with delayed union in addition to the femoral neck non-union will pose major problems at operation. We share our experience in treating a femoral neck fracture non-union with ipsilateral femoral shaft delayed union in the shaft and in the distal femur in a fifty years old patient. The fracture was treated with an angle blade plate and supracondylar nail supplemented with a free vascularised fibular bone grafting and autologous cancellous graft. There was radiological union at fourth month. At sixth months, the patient was free of pain and able to walk without support. Thus, we would like to suggest that vascularised fibula bone grafting with supracondylar nailing is a viable option for this pattern of fracture.

Incidence of post-operative pain following single visit endodontics in vital and non-vital teeth: An in vivo study

Science.gov (United States)

Bhagwat, Sumita; Mehta, Deepil

2013-01-01

This clinical study was conducted to compare the post-operative pain following single visit endodontics in vital and non-vital teeth, with and without periapical radiolucency. A total of 60 adult patients requiring root canal therapy in anterior and premolar teeth were selected for this study. Single sitting root canal treatment was carried out and the subjects were recalled after 2 weeks and instructed to fill out a series of self-report questionnaires for responses about pain in the interim after 1 day, 2 day, 3 day, 1 week and 2 weeks. In vital teeth (Group I) 60% of the treated cases had pain, of which 36% had mild pain (non-significant) and 24% had moderate pain (significant). In non-vital teeth without periapical radiolucency (Group II) 64% of cases had pain, of which 48% had mild pain (non-significant) and 16% had moderate pain (significant). In non-vital teeth with periapical radiolucency (Group III) 32% of the cases had pain of which 24% had mild pain (non-significant) and 8% had moderate pain (significant). None of the teeth in any of the groups had severe pain. There was no statistical difference between incidence of pain in vital and non-vital teeth without periapical radiolucency. Non-vital teeth with periapical radiolucency exhibited relatively less pain as compared with non-vital teeth without periapical radiolucency, but the pain continued in a significant percent of teeth even after 2 weeks. Pain incidence dropped significantly within a period of 1 day to 2 weeks in vital teeth and non-vital teeth without periapical radiolucency. There was a tendency for less incidence of significant pain after a single visit root canal treatment in these groups. Results obtained were comparable with those obtained by several investigators. PMID:24124293

Broncho-pulmonary toxicity in stage III non small cell lung cancer patients treated with taxol containing chemotherapy and concurrent preoperative or definitive radiation therapy

International Nuclear Information System (INIS)

Sharma, M. Maddie; Gupta-Burt, Shalina; Recine, Diane C.; Faber, L. Penfield; Warren, William H.; LaFollette, Suzanne; Lincoln, Sarah T.; Bonomi, Philip D.

1997-01-01

Purpose/Objective: The objective of this trial was to test the feasibility of taxol containing combination chemotherapy and concurrent radiation as preoperative or definitive treatment for stage III non small cell lung cancer patients. Methods and Materials: Thirty-three patients were treated on this trial. The initial regimen was (Group 1 pts.): paraplatin (P) (AUC of 4) on day 2, etoposide (E) 50 mg po days 1-5 and 8-12, cisplatin (C) 50 mg/m2 on day 21 and taxol (T) 35 mg/m2 escalated to 45 mg/m2 on days 1 and 8, 24 hr. infusion. After treatment of 10 pts., the regimen was modified as follows (Group 2 pts.): P (AUC of 4) on day 1, E 40 mg/m2 IV daily and days 2-5, and T 80 mg/m2 escalated to 120 mg/m2 on day 1, 3 hr. infusion. After the next 16 pts., the regimen was modified again as follows (Group 3 pts.): P (AUC of 4) on day 1 and T 120 mg/m2 escalated to 140 mg/m2 on day 1, 3 hr. infusion. Seven patients were treated on the latest version of the regimen for a total of 33 pts. The radiation given was uniform throughout the 3 groups. A dose of 4000 cGy in 20 fxs was given in the surgical arm and 6000 cGy in 30 fxs in the non surgical arm. Treatments were given at 200 cGy/fx. once a day, on a 2 weeks on, 2 weeks off basis. The RTOG Acute Radiation Morbidity Scoring Criteria was used to grade pneumonitis. Post-operative complications were defined as occurring early (less than or equal to 30 days) or late (greater than 30 days) following surgery. Results: Sixteen of the 33 patients went to surgery. Grade 3 radiation pneumonitis developed in 4 of the 33 patients (12%). There were no episodes of Grade 4 pneumonitis. Grade 3 pneumonitis occured in: One patient in Group 1, (RT dose 5800 cGy), 2 pts in Group 2 (RT dose 4000 cGy and 6000 cGy, respectively), and 1 pt in Group 3 (RT dose 6000 cGy). Major post-operative complications occurred in 6 of the 16 patients (37.5%) who went to surgery. In Group 1, 1 pt. required oxygen supplementation secondary to a significant

Shoulder morbidity after non-surgical treatment of the neck

International Nuclear Information System (INIS)

Wouwe, Merian van; Bree, Remco de; Kuik, Dirk J.; Goede, Cees J.T. de; Verdonck-de Leeuw, Irma M.; Doornaert, Patricia; Rene Leemans, C.

2009-01-01

Background and purpose: Reports on shoulder function after non-surgical treatment are not available. In the present study shoulder morbidity after surgical and non-surgical treatment of the neck is determined and compared. Materials and methods: In 100 head and neck cancer patients 174 neck sides were treated by surgery (n = 51) or (chemo)radiation (n = 123). Abduction, anteflexion, endorotation and exorotation were assessed. Subjective measurements were performed using the Visual Analogue Scale for pain, the Shoulder Disability Questionnaire (SDQ) and stiffness reporting. Results: Predictive factors for SDQ-score > 0 (n = 54) were VAS pain score, stiffness, abduction, anteflexion, physiotherapy, low shoulder position and surgical treatment. The SDQ, stiffness and pain scores were significantly higher in the surgically treated group than in the non-surgical group (p < 0.01). Anteflexion, abduction and exorotation were less impaired in the non-surgically treated group than in the surgically treated group (p < 0.01). No differences between neck dissection and neck dissection with post-operative radiotherapy, and radiotherapy and chemoradiation were found for these movements. Conclusions: Shoulder morbidity is often present after non-surgical treatment of the neck, but to a lesser extent compared to surgical treatment. Radiotherapy adds no morbidity to neck dissection and chemotherapy does not add extra morbidity to primary radiation

Use of face masks by non-scrubbed operating room staff: a randomized controlled trial.

Science.gov (United States)

Webster, Joan; Croger, Sarah; Lister, Carolyn; Doidge, Michelle; Terry, Michael J; Jones, Ian

2010-03-01

Ambiguity remains about the effectiveness of wearing surgical face masks. The purpose of this study was to assess the impact on surgical site infections (SSIs) when non-scrubbed operating room staff did not wear surgical face masks. Eight hundred twenty-seven participants undergoing elective or emergency obstetric, gynecological, general, orthopaedic, breast or urological surgery in an Australian tertiary hospital were enrolled. Complete follow-up data were available for 811 patients (98.1%). Operating room lists were randomly allocated to a 'Mask group' (all non-scrubbed staff wore a mask) or 'No Mask group' (none of the non-scrubbed staff wore masks). The primary end point, SSI was identified using in-patient surveillance; post discharge follow-up and chart reviews. The patient was followed for up to six weeks. Overall, 83 (10.2%) surgical site infections were recorded; 46/401 (11.5%) in the Masked group and 37/410 (9.0%) in the No Mask group; odds ratio (OR) 0.77 (95% confidence interval (CI) 0.49 to 1.21), p = 0.151. Independent risk factors for surgical site infection included: any pre-operative stay (adjusted odds ratio [aOR], 0.43 (95% CI, 0.20; 0.95), high BMI aOR, 0.38 (95% CI, 0.17; 0.87), and any previous surgical site infection aOR, 0.40 (95% CI, 0.17; 0.89). Surgical site infection rates did not increase when non-scrubbed operating room personnel did not wear a face mask.

Roentgenographic findings in hyaline membrane disease treated with exogenous surfactant: comparison with control group

International Nuclear Information System (INIS)

Lee, Sun Kyoung; Lim, Chae Ha; Lim, Woo Young; Kim, Young Sook; Byen, Ju Nam; Oh, Jae Hee; Kim, Young Chul

1997-01-01

To compare, with the use of chest radiographic findings, improvement and complications in newborns treated with exogenous surfactant for hyaline membrane disease (HMD), and an untreated control group. Thirty-six patients with HMD were randomly assigned to a control group (n=18) or surfactant treated group (n=18). As part of an initial evaluation of their pulmonary status, we then performed a retrospective statistical analysis of chest radiographic findings obtained in exogenous surfactant treated and untreated infants within the first 90 minutes of life. Subsequent examinations were performed at less than 24 hours of age. Chest radiograph before treatment showed no significant differences between the two groups, but significant improvement was noted in the surfactant treated group, in contrast to the control group. The most common chest radiographic finding after surfactant administration was uniform (n=15) or disproportionate (n=2) improvement of pulmonary aeration. Patent ductus arteriosus developed in three treated neonates and in four cases in the control group. Air leak occurred in three cases in the treated group and in five cases in the control group. In one treated patient pulmonary hemorrhage developed and intracranial hemorrhage occurred in three treated neonates and in four cases in the control group. Bronchopulmonary dysplasia was developed in 6 cases of treated group and 3 cases of control group. A chest radiograph is considered to be helpful in the evaluation of improvement and complications of HMD in infants treated with surfactant

Pre-treating water with non-thermal plasma

Science.gov (United States)

Cho, Young I.; Fridman, Alexander; Rabinovich, Alexander; Cho, Daniel J.

2017-07-04

The present invention consists of a method of pre-treatment of adulterated water for distillation, including adulterated water produced during hydraulic fracturing ("fracking") of shale rock during natural gas drilling. In particular, the invention is directed to a method of treating adulterated water, said adulterated water having an initial level of bicarbonate ion in a range of about 250 ppm to about 5000 ppm and an initial level of calcium ion in a range of about 500 ppm to about 50,000 ppm, said method comprising contacting the adulterated water with a non-thermal arc discharge plasma to produce plasma treated water having a level of bicarbonate ion of less than about 100 ppm. Optionally, the plasma treated water may be further distilled.

Workshop on Non-Associative & Non-Commutative Algebra and Operator Theory

CERN Document Server

Molina, Mercedes

2016-01-01

Presenting the collaborations of over thirty international experts in the latest developments in pure and applied mathematics, this volume serves as an anthology of research with a common basis in algebra, functional analysis and their applications. Special attention is devoted to non-commutative algebras, non-associative algebras, operator theory and ring and module theory. These themes are relevant in research and development in coding theory, cryptography and quantum mechanics. The topics in this volume were presented at the Workshop on Non-Associative & Non-Commutative Algebra and Operator Theory, held May 23—25, 2014 at Cheikh Anta Diop University in Dakar, Senegal in honor of Professor Amin Kaidi. The workshop was hosted by the university's Laboratory of Algebra, Cryptology, Algebraic Geometry and Applications, in cooperation with the University of Almería and the University of Málaga. Dr. Kaidi's work focuses on non-associative rings and algebras, operator theory and functional analysis, and he...

The long-term functional outcome of type II odontoid fractures managed non-operatively.

LENUS (Irish Health Repository)

Butler, J S

2010-10-01

Odontoid fractures currently account for 9-15% of all adult cervical spine fractures, with type II fractures accounting for the majority of these injuries. Despite recent advances in internal fixation techniques, the management of type II fractures still remains controversial with advocates still supporting non-rigid immobilization as the definitive treatment of these injuries. At the NSIU, over an 11-year period between 1 July 1996 and 30 June 2006, 66 patients (n = 66) were treated by external immobilization for type II odontoid fractures. The medical records, radiographs and CT scans of all patients identified were reviewed. Clinical follow-up evaluation was performed using the Cervical Spine Outcomes Questionnaire (CSOQ). The objectives of this study were to evaluate the long-term functional outcome of patients suffering isolated type II odontoid fractures managed non-operatively and to correlate patient age and device type with clinical and functional outcome. Of the 66 patients, there were 42 males and 24 females (M:F = 1.75:1) managed non-operatively for type II odontoid fractures. The mean follow-up time was 66 months. Advancing age was highly correlated with poorer long-term functional outcomes when assessing neck pain (r = 0.19, P = 0.1219), shoulder and arm pain (r = 0.41, P = 0.0007), physical symptoms (r = 0.25, P = 0.472), functional disability (r = 0.24, P = 0.0476) and psychological distress (r = 0.41, P = 0.0007). Patients >65 years displayed a higher rate of pseudoarthrosis (21.43 vs. 1.92%) and established non-union (7.14 vs. 0%) than patients <65 years. The non-operative management of type II odontoid fractures is an effective and satisfactory method of treating type II odontoid fractures, particularly those of a stable nature. However, patients of advancing age have been demonstrated to have significantly poorer functional outcomes in the long term. This may be linked to higher rates of non-union.

Absorption edge imaging of sporocide-treated and non-treated bacterial spores

International Nuclear Information System (INIS)

Panessa-Warren, B.J.; Tortora, G.T.; Warren, J.B.

1987-01-01

When deprived of nutrients, spore forming bacilli produce endospores which are remarkably resistant to chemical sterilization. Little is known about the morphology and response fo these spores following exposure to sporocidal agents. Light microscopy does not provide sufficient resolution for studying the rupture of the spore coat and fate of intracellular material. Transmission and scanning electron microscopy offer superior resolution but require specimen preparation methods that induce physiologic as well as morphologic changes in the spores, thereby making accurate interpretation of micrographs difficult. To eliminate the possible artifacts induced by chemical fixation, dehydration, embeddment, staining and sectioning, treated and non-sporocide-treated endospores of B. thuringiensis and B. subtilis were imaged by x-ray contact microscopy using monochromatic x-rays. 6 refs., 2 figs

Auto-tuning Non-blocking Collective Communication Operations

KAUST Repository

Barigou, Youcef; Venkatesan, Vishwanath; Gabriel, Edgar

2015-01-01

Collective operations are widely used in large scale scientific applications, and critical to the scalability of these applications for large process counts. It has also been demonstrated that collective operations have to be carefully tuned for a given platform and application scenario to maximize their performance. Non-blocking collective operations extend the concept of collective operations by offering the additional benefit of being able to overlap communication and computation. This paper presents the automatic run-time tuning of non-blocking collective communication operations, which allows the communication library to choose the best performing implementation for a non-blocking collective operation on a case by case basis. The paper demonstrates that libraries using a single algorithm or implementation for a non-blocking collective operation will inevitably lead to suboptimal performance in many scenarios, and thus validate the necessity for run-time tuning of these operations. The benefits of the approach are further demonstrated for an application kernel using a multi-dimensional Fast Fourier Transform. The results obtained for the application scenario indicate a performance improvement of up to 40% compared to the current state of the art.

Auto-tuning Non-blocking Collective Communication Operations

KAUST Repository

Barigou, Youcef

2015-05-01

Collective operations are widely used in large scale scientific applications, and critical to the scalability of these applications for large process counts. It has also been demonstrated that collective operations have to be carefully tuned for a given platform and application scenario to maximize their performance. Non-blocking collective operations extend the concept of collective operations by offering the additional benefit of being able to overlap communication and computation. This paper presents the automatic run-time tuning of non-blocking collective communication operations, which allows the communication library to choose the best performing implementation for a non-blocking collective operation on a case by case basis. The paper demonstrates that libraries using a single algorithm or implementation for a non-blocking collective operation will inevitably lead to suboptimal performance in many scenarios, and thus validate the necessity for run-time tuning of these operations. The benefits of the approach are further demonstrated for an application kernel using a multi-dimensional Fast Fourier Transform. The results obtained for the application scenario indicate a performance improvement of up to 40% compared to the current state of the art.

Bicytopenia, especially thrombocytopenia in hemodialysis and non-hemodialysis patients treated with linezolid therapy.

Science.gov (United States)

Kato, Hideo; Hamada, Yukihiro; Hagihara, Mao; Hirai, Jun; Yamagishi, Yuka; Matsuura, Katsuhiko; Mikamo, Hiroshige

2015-10-01

One of the major adverse events associated with linezolid treatment is pancytopenia. However, there are few reports about the tolerability of linezolid among patients undergoing hemodialysis. This study retrospectively investigated the frequency of bicytopenia (thrombocytopenia and erythropenia) secondary to linezolid treatment in patients undergoing and not-undergoing hemodialysis. In total, 181 patients treated with linezolid from January 2010 to July 2012 at Aichi Medical University Hospital were divided into three groups; patients undergoing hemodialysis (HD group), those with creatinine clearance (CLCR) of linezolid therapy were compared among three groups. Thrombocytopenia (linezolid therapy. In particular, the PLT nadir in HD group occurred earlier than that in non-HD groups (HD, 11.5 days [4-31 days]; CLCR linezolid treatment in patients undergoing hemodialysis. Copyright © 2015 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

and Non-Operable Tracheal Stenosis

Directory of Open Access Journals (Sweden)

Reza Bagheri

2013-05-01

Full Text Available   Introduction: Tracheal stenosis is normally caused by trauma, infection, benign and malignant tumors, prolonged intubation or tracheostomy. The best treatment for tracheal stenosis is resection and anastomosis of trachea. Yet the major surgical complication of tracheal surgery is postoperative stenosis. The goal of this paper is to study the result of tracheal stenting as a replacement therapy for patients suffering from tracheal stenosis who are not good candidates for surgery.   Materials and Methods: This study presents the results of stenting in patients with: Inoperable tumoral stenosis,Non-tumoral stenosis being complicated due to prior surgeries,Inability to undergo a major surgery.The study was performed between September 2002 and July 2011 and poly flex stents were used by means of rigid bronchoscopy. Results: A total of 25 patients received stents during this study. Among them 15 patients suffered from benign and 10 suffered from malignant tracheal stenosis. The patients were followed up for at most 12 months after the stenting operation. The mean age of the patients was 35 years. The most common cause of stenosis was prolonged intubation (75%. The most common indication for stenting was the history of multiple tracheal operations. The most common complication of stenting and cause of stent removal was formation of granulation tissue. 30% of patients with benign tracheal stenosis were cured and about 10% improved until they could stand a major operation. Ten patients in benign group and 2 patients in malignant group (20% needed T-Tube insertion after stent removal but other patientcure by stenting. Conclusions: In benign cases stenting is associated with recurrence of symptoms which requires other therapeutic techniqus, so the stenting may not be named as a final solution in benign cases. However, this technique is the only method with approved efficacy for malignant cases with indication.

Study of vitamin D serum level in patients with epilepsy treated with enzyme-inducing and non enzyme-inducing medications

Directory of Open Access Journals (Sweden)

sima Hashemipour

2014-01-01

Full Text Available Background : Changes of serum minerals and vitamin D have been reported in anticonvulsant drugs user patients. The present study aimed at comparing the changes of serum minerals and vitamin D among two groups of enzyme-inducing and non enzyme-inducing anticonvulsant drug users. Methods: In this study 22 patients treated with enzyme-inducing drugs (carbamazepin, phenytoin, phenobarbital were compared to 25 patients of matched sex, age, and BMI treated with non enzyme-inducing drugs (sodium evaporate, lamotrigine. Serum calcium, phosphate, parathormone, and 25-hydroxy vitamin D were calculated in both groups. Calcium was measured by Calorimetery method. Parathormone and vitamin D were measured using ELISA method. Results: The mean serum vitamin D level was lower in enzyme-inducing than non enzyme-inducing drugs users (15.9±8.3 and 24.2±14.8, P=0.02. Frequency of vitamin D deficiency was higher in enzyme-inducing compared to non enzyme-inducing drugs users, 84% and 48% , respectively (P=0.016. The mean serum calcium level was significantly lower in enzyme-inducing drugs users. (8.7±0.2 vs. 9.0± 0.7, p= 0.05. Four percent in enzyme-inducing group compared to twenty four percent of non enzyme-inducing group had secondary hyperparathyroidism (P=0.016. Conclusion: While vitamin D deficiency is more frequent in enzyme-inducing drug users, secondary hyperparathyroidism is less frequent.

Schwarzian conditions for linear differential operators with selected differential Galois groups

International Nuclear Information System (INIS)

Abdelaziz, Y; Maillard, J-M

2017-01-01

We show that non-linear Schwarzian differential equations emerging from covariance symmetry conditions imposed on linear differential operators with hypergeometric function solutions can be generalized to arbitrary order linear differential operators with polynomial coefficients having selected differential Galois groups. For order three and order four linear differential operators we show that this pullback invariance up to conjugation eventually reduces to symmetric powers of an underlying order-two operator. We give, precisely, the conditions to have modular correspondences solutions for such Schwarzian differential equations, which was an open question in a previous paper. We analyze in detail a pullbacked hypergeometric example generalizing modular forms, that ushers a pullback invariance up to operator homomorphisms. We finally consider the more general problem of the equivalence of two different order-four linear differential Calabi–Yau operators up to pullbacks and conjugation, and clarify the cases where they have the same Yukawa couplings. (paper)

Schwarzian conditions for linear differential operators with selected differential Galois groups

Science.gov (United States)

Abdelaziz, Y.; Maillard, J.-M.

2017-11-01

We show that non-linear Schwarzian differential equations emerging from covariance symmetry conditions imposed on linear differential operators with hypergeometric function solutions can be generalized to arbitrary order linear differential operators with polynomial coefficients having selected differential Galois groups. For order three and order four linear differential operators we show that this pullback invariance up to conjugation eventually reduces to symmetric powers of an underlying order-two operator. We give, precisely, the conditions to have modular correspondences solutions for such Schwarzian differential equations, which was an open question in a previous paper. We analyze in detail a pullbacked hypergeometric example generalizing modular forms, that ushers a pullback invariance up to operator homomorphisms. We finally consider the more general problem of the equivalence of two different order-four linear differential Calabi-Yau operators up to pullbacks and conjugation, and clarify the cases where they have the same Yukawa couplings.

Non-Archimedean analogues of orthogonal and symmetric operators

International Nuclear Information System (INIS)

Albeverio, S; Bayod, J M; Perez-Garsia, C; Khrennikov, A Yu; Cianci, R

1999-01-01

We study orthogonal and symmetric operators on non-Archimedean Hilbert spaces in connection with the p-adic quantization. This quantization describes measurements with finite precision. Symmetric (bounded) operators on p-adic Hilbert spaces represent physical observables. We study the spectral properties of one of the most important quantum operators, namely, the position operator (which is represented on p-adic Hilbert L 2 -space with respect to the p-adic Gaussian measure). Orthogonal isometric isomorphisms of p-adic Hilbert spaces preserve the precision of measurements. We study properties of orthogonal operators. It is proved that every orthogonal operator on non-Archimedean Hilbert space is continuous. However, there are discontinuous operators with dense domain of definition that preserve the inner product. There exist non-isometric orthogonal operators. We describe some classes of orthogonal isometric operators on finite-dimensional spaces. We study some general questions in the theory of non-Archimedean Hilbert spaces (in particular, general connections between the topology, norm and inner product)

Acute high-grade acromioclavicular joint injuries: quality of life comparison between patients managed operatively with a hook plate versus patients managed non-operatively.

Science.gov (United States)

Natera Cisneros, Luis Gerardo; Sarasquete Reiriz, Juan

2017-04-01

Surgical indication for acromioclavicular joint (ACJ) injuries still represents a reason for shoulder and trauma debate. In high-grade injuries, surgery is advocated because some of the non-operatively managed patients may have persistent shoulder pain that could make them unable to return to their previous activity. It has been shown that many of the patients with high-grade ACJ injuries that are managed non-operatively involve the development of scapular dyskinesis, situation that may result in loss of strength and weakness. On the other side, it has been widely reported that the period while the hook plate is present involves functional limitations and pain. The purpose of this study was to compare the quality of life (QoL) of patients with acute high-grade ACJ injuries (Rockwood grade III-V), managed operatively with a hook plate versus the QoL of patients managed non-operatively, 24 months or more after shoulder injury. Patients with acute high-grade ACJ injuries managed operatively (hook plate) or non-operatively, between 2008 and 2012 were included. The QoL was evaluated by means of the Health Survey questionnaire (SF36), the Visual Analogue Scale (VAS) for pain, the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire, the Constant score and the Global Satisfaction (scale from 0 to 10) assessed at the last follow-up visit. The presence of scapular dyskinesis was assessed. Comparison between groups was made. Thirty-two patients were included: 11 hook plate-group (PLATE group) (5 Rockwood III and 6 V) and 21 conservative-group (CONS group) (4 Rockwood III and 17 V). The mean age was 41 [19-55] years old for the PLATE group and 38 [19-55] for the CONS group (p = 0.513). The mean follow-up was 32.50 ± 11.64 months for the PLATE group and 34.77 ± 21.98 months for the CONS group (p = 0.762). The mean results of the questionnaires assessed at the last follow-up visit were: (1) physical SF36 score (PLATE group 53.70 ± 4.33 and CONS group

Representations of the Poincare group, position operator and the bi-local model

International Nuclear Information System (INIS)

Sohkawa, Tohru

1978-01-01

We propose two types of representations of the Poincare group which give general frameworks for introduction of internal degrees of freedom of a particle. The bi-local model recently proposed by Takabayasi is constructed through our frameworks. In this study, new covariant and non-covariant position operators are introduced and discussed. (author)

Treatment results in anal cancer: non-operative treatment versus operative treatment

Energy Technology Data Exchange (ETDEWEB)

Chie, Eui Kyu; Park, Jae Gahb; Bang, Yung Jue; Heo, Dae Seog; Kim, Noe Kyeong [Seoul National University College of Medicine, Seoul (Korea, Republic of); Ha, Sung Whan [Medical Reasearch Center, Seoul National University, Seoul (Korea, Republic of)

2002-03-15

This study was undertaken to analyze the efficacy and sphincter preservation rate of platinum based neoadjuvant chemotherapy plus radiotherapy versus abdominoperineal resection and postoperative radiotherapy for anal cancer. Data of forty-two patients with anal cancer were retrospectively analyzed. Among thirty-eight patients with epidermoid histology, four patients received radiotherapy, and nineteen patients received abdominoperineal resection and adjuvant radiotherapy with or without chemotherapy (APR + RT {+-} CT), and fifteen patients received neoadjuvant chemotherapy and radiotherapy (CRT). The CRT regimen was composed of three cycles of 5-fluorouracil (1,000 mg/m{sup 2} bolus on D1 {approx} 5) and cisplatin (60 mg/m{sup 2} bolus on D1) followed by 50.4 Gy to the tumor bed and regional lymphatics over 5.5 weeks. Both inguinal lymphatics were treated with an identical dose schedule. Residual disease was treated with an additional three cycles of identical adjuvant chemotherapy. An identical dose schedule was used for post-operative radiotherapy. Median follow-up period was eighty-five months. Overall five-year survival rates were 80.3%, 88.9% and 79.4% for entire patients, APR + RT {+-} CT group, and the CRT group, respectively. No significant difference was found between the two groups ({rho} = 0.49). Anus preservation rate for the CRT group was 86.7%. Age ({rho} = 0.0164) and performance status ({rho} = 0.0007) were found to be significant prognostic factors by univariate analysis. Age ({rho} = 0.0426), performance status ({rho} = 0.0068), and inguinal lymph node metastasis ({rho} = 0.0093) were statistically significant prognostic factors by multivariate analysis. No case of RTOG grade 3 complication or higher was reported. This and other recent studies have shown that combined chemotherapy plus radiotherapy for anal cancer results in a high rate of anal sphincter preservation as well as local control and survival. Furthermore, neoadjuvant use of

Non-operative diagnosis - effect on repeat-operation rates in the UK breast screening programme

International Nuclear Information System (INIS)

Wallis, M.G.; Cheung, S.; Kearins, O.; Lawrence, G.M.

2009-01-01

Non-operative diagnosis rates in the UK breast screening programme have improved dramatically from 48.8% in 1994/95 (only nine units achieved the then minimum standard of 70%) to 94% in 2005/06 (only seven units failed to achieve the target of 90%). Preoperative and operative history of all 120,550 women diagnosed with screen-detected breast cancer in the UK between April 1994 and March 2006 was derived from different national databases. In 2005/06, 2,790 (17.8%) of the 15,688 women having surgery needed two or more operations. In 2001/02 (non-operative diagnosis rate 87%), the re-operation rate was 23.8% (2,377 of 9,969). Extrapolation backwards to 1994/95 (non-operative diagnosis rate 48.8%) suggests a re-operation rate of 62%. Analysis over the 4 years from April 2002 (n=34,198) demonstrates that 4,089 (12%) women with a correct non-operative diagnosis of invasive disease required additional surgery compared to 1,166 (48%) of women who were under-staged (diagnosed as non-invasive based on core biopsy, but actually suffering from invasive disease). Failure to achieve a non-operative diagnosis of invasive disease (n=1,542) or non-invasive disease (n=2,247) resulted in re-operation rates of 65 and 43% respectively. Given the impact of not having a diagnosis pre-operatively, or of under-staging invasive carcinoma, it seems timely to introduce more sophisticated standards. (orig.)

Posterior Cruciate Ligament Tibial Avulsion treated with Open Reduction and Internal Fixation

Directory of Open Access Journals (Sweden)

Lee WXP

2015-07-01

Full Text Available The optimal treatment for thoracolumbar fractures (TLF without neurological deficit remains controversial. Majority of the systematic reviews and meta-analyses have evaluated open operative approaches but have yet to compare the outcomes of minimally invasive percutaneous pedicle fixation (MIPPF versus non-operative treatment. A retrospective cohort study was performed to compare clinical and radiological outcomes between MIPPF and conservative groups for TLF AO Type A1 to Type B2 during a 2-year follow-up period. Pre-operative plain and CT films were evaluated and decision made for short segment (non-fusion MIPPF. Patients who refused operation were treated conservatively with three months of body cast, brace, or corset. MIPPF group showed earlier Visual Analog Score (VAS improvement at six months post-injury (0 vs 6.0- p0.050. MIPPF as a method of internal bracing can be pursued in the treatment of TLF, with larger future cohorts and RCTs being called for to support and explore new findings.

Classical prognostic factors in patients with non-advanced endometrial cancer treated with postoperative radiotherapy

International Nuclear Information System (INIS)

Karolewski, K.; Kojs, Z.; Jakubowicz, J.; Urbanski, K.; Michalak, A.

2006-01-01

Aim: Analysis of classical prognostic factors in patients with non-advanced endometrial cancer treated with postoperative radiotherapy. Materials/Methods: In the years 1985 - 1999, 705 patients underwent postoperative radiotherapy due to endometrial cancer: 529 patients with FIGO stage I and 176 with FIGO stage II cancer. Mean age was 58 years. In 96% of patients endometrioid adenocarcinoma was found. In 49.9% the cancer had a high, in 27.9% a medium, and in 22.2% a low degree of differentiation. Results: 82% of patients had 5-year disease-free survival. In univariate analysis a significantly higher rate of disease-free survival was observed in: patients younger than 60, with moderately and well differentiated cancers, with stage I endometrioid adenocarcinoma with less than 50% myometrial invasion. In multivariate analysis degree of cancer differentiation was the only independent prognostic factor. Conclusions: In a group of patients with non-advanced endometrial cancer treated with postoperative radiotherapy, degree of cancer differentiation is the primary prognostic factor. (authors)

Compact groups of positive operators on Banach lattices

NARCIS (Netherlands)

Jeu, de M.F.E.; Wortel, M.R.

2014-01-01

In this paper, we study groups of positive operators on Banach lattices. If a certain factorization property holds for the elements of such a group, the group has a homomorphic image in the isometric positive operators which has the same invariant ideals as the original group. If the group is

A Novel Therapeutic Frame for Treating Depression in Group Treating Depression Downhill

OpenAIRE

Valery Krupnik

2014-01-01

We describe an original protocol Treating Depression Downhill (TDD) that was designed as a specific therapy for depression. Evolutionary theories of depression served as a basis for its development. We discuss the rationale for using evolutionary theory and describe the structure and integrative nature of TDD. We then present an observation on TDD’s application to group therapy of active duty military personnel. In the...

Working group on unbundling of electricity trade operations 2. A group report

International Nuclear Information System (INIS)

2000-09-01

The current unbundling of operations in accounts has proved inadequate. No formula or model that could be made binding by provisions have been defined for unbundled accounts. In addition, unbundling can draw a distinct line between commercial activities and network operations, which have assumed various authoritative functions. Against this background, the need for clearer unbundling has become more marked. The working group suggests that the current provisions on unbundling of trade operations should be tightened and that the unbundling should be made clearer especially in terms of allocation of joint costs. For this, the necessary preparations by the authorities should be initiated urgently. At the same time, the working group proposes that network operations should be unbundled from other operations by incorporation or by unbundling them into a separate public utility. The smallest electric utilities should be exempted from the obligation of incorporating network operations. According to the working group, the lower limit could be fixed e.g. at 70 GWh a year. The working group also suggests that the licensees must own the electricity networks they operate. The licensees could not rent their networks from the mother company nor lease them from a financing company. The model proposed by the working group would redress the major problems connected with the supervision of the electricity market. The monopoly, i.e. the electricity network operations, under the supervision of the Electricity Market Authority could thus be unbundled. This would improve the functioning of the market and facilitate the supervision. However, the model would not abolish the tax concession of municipal public utilities in competitive trade operations, production and sale of electricity. The tax concession may affect the competitive situation on the electricity market. (orig.)

Linear representation of algebras with non-associative operations which are satisfy in the balanced functional equations

International Nuclear Information System (INIS)

Ehsani, Amir

2015-01-01

Algebras with a pair of non-associative binary operations (f, g) which are satisfy in the balanced quadratic functional equations with four object variables considered. First, we obtain a linear representation for the operations, of this kind of binary algebras (A,f,g), over an abelian group (A, +) and then we generalize the linear representation of operations, to an algebra (A,F) with non-associative binary operations which are satisfy in the balanced quadratic functional equations with four object variables. (paper)

Treating iron overload in patients with non-transfusion-dependent thalassemia

Science.gov (United States)

Taher, Ali T; Viprakasit, Vip; Musallam, Khaled M; Cappellini, M Domenica

2013-01-01

Despite receiving no or only occasional blood transfusions, patients with non-transfusion-dependent thalassemia (NTDT) have increased intestinal iron absorption and can accumulate iron to levels comparable with transfusion-dependent patients. This iron accumulation occurs more slowly in NTDT patients compared to transfusion-dependent thalassemia patients, and complications do not arise until later in life. It remains crucial for these patients' health to monitor and appropriately treat their iron burden. Based on recent data, including a randomized clinical trial on iron chelation in NTDT, a simple iron chelation treatment algorithm is presented to assist physicians with monitoring iron burden and initiating chelation therapy in this group of patients. Am. J. Hematol. 88:409–415, 2013. © 2013 Wiley Periodicals, Inc. PMID:23475638

Decisions concerning how to improve operator performance based on comparisons of successful and non-successful operators

International Nuclear Information System (INIS)

Svenson, Ola

1999-01-01

One way of finding out how to improve operator training is to collect information from expert operators about how they select and process information when they act as experts. This strategy can be used when the information is not well structured, when expertise involves a very high level of skill and so forth. X-ray diagnosis, evaluations of organizations, judgments of rock and materials quality over very long time and investigations of cracks in ultrasonic tests exemplify areas in which human expertise plays an important role. Typically, in this kind of approach, a number of skilled experts are first selected and then they are compared to a control group of less successful individuals or non-experts (who can also in some cases be the candidates of the training program). The differences between the two groups are then used as a basis for designing training programs to improve the performance of the non-experts. Unfortunately, this approach has some pitfalls that may lead to undue optimism concerning the expected results of such training programs. This will be further elaborated and exemplified in this talk (full text of the contribution)

Non-perturbative renormalization of left-left four-fermion operators in quenched lattice QCD

CERN Document Server

Guagnelli, M; Peña, C; Sint, S; Vladikas, A

2006-01-01

We define a family of Schroedinger Functional renormalization schemes for the four-quark multiplicatively renormalizable operators of the $\\Delta F = 1$ and $\\Delta F = 2$ effective weak Hamiltonians. Using the lattice regularization with quenched Wilson quarks, we compute non-perturbatively the renormalization group running of these operators in the continuum limit in a large range of renormalization scales. Continuum limit extrapolations are well controlled thanks to the implementation of two fermionic actions (Wilson and Clover). The ratio of the renormalization group invariant operator to its renormalized counterpart at a low energy scale, as well as the renormalization constant at this scale, is obtained for all schemes.

[Non operative treatment for perforated peptic ulcer: results of a prospective study].

Science.gov (United States)

Songne, B; Jean, F; Foulatier, O; Khalil, H; Scotté, M

2004-12-01

The conservative management of perforated peptic ulcer has not gained widespread acceptance despite introduction of proton-pomp inhibitors because surgical procedures can achieve immediate closure by eventually using a laparoscopic approach. The aim of this prospective study was to evaluate the results of Taylor's method and to identify predictive factors of failure of medical treatment in patients presenting with perforated peptic ulcer. Between 1990 and 2000, 82 consecutive patients, with diagnosis of perforated peptic ulcer were prospectively included in this study. They were initially treated with non-operative procedure (nasogastric suction and intravenous administration of H2-blockers or proton-pomp inhibitors). No clinical improvement after 24 hours required a surgical treatment. Predictive factors of failure of non-operative treatment were tested in univariate or multivariate analysis. Clinical improvement was obtained with non-operative treatment in 54% of the patients (44/82). The overall mortality rate was 1%. In univariate analysis, significant predictive factors of failure of non-operative treatment were: size of pneumoperitoneum, heart beat >94 bpm, abdominal meteorism, pain at digital rectal exam, and age >59 years. In multivariate analysis, the significant factors were the size of pneumoperitoneum, heart beat, and abdominal meteorism. The association of these criteria: size of pneumoperitoneum >size of the first lumbar vertebra, heart beat >94 bpm, pain at digital rectal exam and age > 59 years , led to surgical treatment in all cases. These results suggest that more than 50% of patients with perforated peptic ulcer respond to conservative treatment without surgery and that the association of few criteria (size of pneumoperitoneum, heart beat, pain at digital rectal exam and age) require emergency surgery.

Rear Operations Group medicine: a pilot study of psychological decompression in a Rear Operations Group during Operation HERRICK 14.

Science.gov (United States)

Nimenko, Wasyl; Simpson, R G

2014-12-01

To investigate group activity psychological decompression (GAPD) in a Rear Operations Group. Provision of military archaeological exercises for a Rear Operations Group's medical centre patients during Op HERRICK 14 with analysis of before and after Patient Health Questionnaires (PHQ), Work and Social Adjustment Scales, generalised anxiety disorder (GAD) 7 Anxiety, Audit Questionnaire and Impact of Events Scale Revised and analysis of interviews with supervisors and soldiers. Soldiers reported a mean of 13%-38% improvement across the self-reported domains. The civilian archaeologists reported improvements in self-esteem, morale and team-working. 10 out of 24 soldiers have expressed an interest to pursue archaeology further; eight soldiers disclosed mental health issues for the first time, four of whom required mental health referral. GAPD can help early-returned soldiers in reducing symptoms of anxiety, depression, isolation and psychological traumatic symptoms. It also helps to increase perception of their ability to work and socialise as a team and help them to an early return to work. It can provide soldiers with the opportunity to approach their supervisors in an informal manner and help in early detection of mental health problems. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Yang-Mills theory for non-semisimple groups

CERN Document Server

Nuyts, J; Nuyts, Jean; Wu, Tai Tsun

2003-01-01

For semisimple groups, possibly multiplied by U(1)'s, the number of Yang-Mills gauge fields is equal to the number of generators of the group. In this paper, it is shown that, for non-semisimple groups, the number of Yang-Mills fields can be larger. These additional Yang-Mills fields are not irrelevant because they appear in the gauge transformations of the original Yang-Mills fields. Such non-semisimple Yang-Mills theories may lead to physical consequences worth studying. The non-semisimple group with only two generators that do not commute is studied in detail.

Meta-ethnography to understand healthcare professionals’ experience of treating adults with chronic non-malignant pain

Science.gov (United States)

Seers, Kate; Barker, Karen L

2017-01-01

Objectives We aimed to explore healthcare professionals’ experience of treating chronic non-malignant pain by conducting a qualitative evidence synthesis. Understanding this experience from the perspective of healthcare professionals will contribute to improvements in the provision of care. Design Qualitative evidence synthesis using meta-ethnography. We searched five electronic bibliographic databases from inception to November 2016. We included studies that explore healthcare professionals’ experience of treating adults with chronic non-malignant pain. We used the GRADE-CERQual framework to rate confidence in review findings. Results We screened the 954 abstracts and 184 full texts and included 77 published studies reporting the experiences of over 1551 international healthcare professionals including doctors, nurses and other health professionals. We abstracted six themes: (1) a sceptical cultural lens, (2) navigating juxtaposed models of medicine, (3) navigating the geography between patient and clinician, (4) challenge of dual advocacy, (5) personal costs and (6) the craft of pain management. We rated confidence in review findings as moderate to high. Conclusions This is the first qualitative evidence synthesis of healthcare professionals’ experiences of treating people with chronic non-malignant pain. We have presented a model that we developed to help healthcare professionals to understand, think about and modify their experiences of treating patients with chronic pain. Our findings highlight scepticism about chronic pain that might explain why patients feel they are not believed. Findings also indicate a dualism in the biopsychosocial model and the complexity of navigating therapeutic relationships. Our model may be transferable to other patient groups or situations. PMID:29273663

Quantum groups, non-commutative differential geometry and applications

International Nuclear Information System (INIS)

Schupp, P.; California Univ., Berkeley, CA

1993-01-01

The topic of this thesis is the development of a versatile and geometrically motivated differential calculus on non-commutative or quantum spaces, providing powerful but easy-to-use mathematical tools for applications in physics and related sciences. A generalization of unitary time evolution is proposed and studied for a simple 2-level system, leading to non-conservation of microscopic entropy, a phenomenon new to quantum mechanics. A Cartan calculus that combines functions, forms, Lie derivatives and inner derivations along general vector fields into one big algebra is constructed for quantum groups and then extended to quantum planes. The construction of a tangent bundle on a quantum group manifold and an BRST type approach to quantum group gauge theory are given as further examples of applications. The material is organized in two parts: Part I studies vector fields on quantum groups, emphasizing Hopf algebraic structures, but also introducing a ''quantum geometric'' construction. Using a generalized semi-direct product construction we combine the dual Hopf algebras A of functions and U of left-invariant vector fields into one fully bicovariant algebra of differential operators. The pure braid group is introduced as the commutant of Δ(U). It provides invariant maps A → U and thereby bicovariant vector fields, casimirs and metrics. This construction allows the translation of undeformed matrix expressions into their less obvious quantum algebraic counter parts. We study this in detail for quasitriangular Hopf algebras, giving the determinant and orthogonality relation for the ''reflection'' matrix. Part II considers the additional structures of differential forms and finitely generated quantum Lie algebras -- it is devoted to the construction of the Cartan calculus, based on an undeformed Cartan identity

Cardiopulmonary morbidity and quality of life in non-small cell lung cancer patients treated with or without postoperative radiotherapy

International Nuclear Information System (INIS)

Kepka, Lucyna; Bujko, Krzysztof; Orlowski, Tadeusz M.; Jagiello, Robert; Salata, Andrzej; Matecka-Nowak, Miroslawa; Janowski, Henryk; Rogowska, Danuta

2011-01-01

Aim: To prospectively assess the cardiopulmonary morbidity and quality of life in patients with non-small cell lung cancer (NSCLC) treated with postoperative radiotherapy (PORT) in comparison to those not receiving PORT. Materials and methods: From 2003 to 2007, 291 patients entered the study; 171 pN2 patients received 3D-planned PORT (PORT group), 120 pN1 patients (non-PORT group) did not. One month after surgery, all patients completed EORTC QLQ C-30 questionnaire and had pulmonary function tests (PFT); cardiopulmonary symptoms were assessed by modified LENT-SOM scale. Two years later, disease-free patients repeated the same examinations. The differences between baseline values and values recorded at two years in QLQ, LENT-SOM and the PFT of the two groups were compared. Results: In the whole cohort, the rate of non-cancer related deaths was 5.3% and 5.0% in PORT and non-PORT group, respectively. Ninety-five patients (47 - PORT group, 48 - non-PORT group) were included into the final analysis. The differences in the QLQ and cardiopulmonary function (LENT/SOM, PFT) between both groups were insignificant. The forced expiratory volume in one second was on average 12.2% and 1.3% better in the PORT and the non-PORT group, respectively, p = 0.2. Conclusions: Our findings support the hypothesis about insignificant morbidity of 3D-planned PORT.

Challenging non-traumatic posterior urethral strictures treated with urethroplasty: a preliminary report

Directory of Open Access Journals (Sweden)

Nicolaas Lumen

2009-08-01

Full Text Available Introduction: Posterior urethral strictures after prostatic radiotherapy or surgery for benign prostatic hyperplasia (BPH refractory to minimal invasive procedures (dilation and/or endoscopic urethrotomy are challenging to treat. Published reports of alternative curative management are extremely rare. This is a preliminary report on the treatment of these difficult strictures by urethroplasty. Materials and Methods: Seven cases were treated: 4 cases occurred after open prostatectomy or transurethral resection of the prostate for BPH, one case after external beam irradiation and 2 after brachytherapy. The 4 cases after BPH-related surgery were in fact complete obstructions at the bladder neck and the membranous urethra with the prostatic urethra still partially patent. Anastomotic repair by perineal route was done in all cases with bladder neck incision in the BPH-cases and prostatic apex resection in the radiotherapy cases. Results: Mean follow-up was 31 months (range: 12-72 months. The operation was successful, with preserved continence, in 3 of the 4 BPH-cases and in 2 of the 3 radiotherapy cases. An endoscopic incision was able to treat a short re-stricture in the BPH-patient and a longer stricture at the bulbar urethra could be managed with a perineostomy in the radiotherapy-patient. Conclusion: Posterior non-traumatic strictures refractory to minimal invasive procedures (dilation/endoscopic urethrotomy can be treated by urethroplasty using an anastomotic repair with a bladder neck incision if necessary.

Elements for Effective Management of Operating Pump and Treat Systems

Science.gov (United States)

This fact sheet summarizes key aspects of effective management for operating pump and treat (P&T) systems based on lessons learned from conducting optimization evaluations at 20 Superfund-financed P&T systems.

Evaluation of a protocol for the non-operative management of perforated peptic ulcer.

Science.gov (United States)

Marshall, C; Ramaswamy, P; Bergin, F G; Rosenberg, I L; Leaper, D J

1999-01-01

The non-operative management of perforated peptic ulcer has previously been shown to be both safe and effective although it remains controversial. A protocol for non-operative management was set up in this hospital in 1989. Adherence to the guidelines in the protocol has been audited over a 6-year period with a review of outcome. The case-notes of patients with a diagnosis of perforated peptic ulcer were reviewed. Twelve guidelines from the protocol were selected for evaluation of compliance to the protocol. Forty-nine patients underwent non-operative treatment initially. Eight patients failed to respond and underwent operation. Complications included abscess formation (seven patients), renal failure (one), gastric ileus (one), chest infection (two), and cardiac failure and stroke (one). Four deaths occurred in this group. Adherence to certain protocol guidelines was poor, notably those concerning prevention of thromboembolism, use of antibiotics, use of contrast examination to confirm the diagnosis and referral for follow-up endoscopy. Two gastric cancers were detected on subsequent endoscopy. This experience demonstrates that non-operative treatment can be used successfully in a general hospital. Adherence to protocol guidelines was found to be variable and the protocol has therefore been simplified. This study highlights the need for an accurate diagnosis and the importance of follow-up endoscopy.

Celebrating 50 years of the CERN Computing Operations group

CERN Multimedia

Katarina Anthony

2013-01-01

Last week, former and current computing operations staff, managers and system engineers were reunited at CERN. They came together to celebrate a milestone not only for the IT Department but also for CERN: the 50th anniversary of the CERN Operations group and the 40th birthday of the Computer Centre.   The reunion was organised by former chief operator, Pierre Bénassi, and took place from 26 to 27 April. Among the 44 attendees were Neil Spoonley and Charles Symons, who together created the Operations group back in 1963. “At that time, working in the Operations group was a very physical job,” recalls former Operations Group Leader, David Underhill. “For that reason, many of the first operators were former firemen.” A few of the participants enjoyed a tour of CERN landmarks during their visit (see photo). The group toured the CERN Computing Centre (accompanied by IT Department Head, Frédéric Hemmer), as well as the ATLAS cav...

[Analysis of the Effect of Non-phacoemulsification Cataract Operation on Corneal Endothelial Cell Nucleus Division].

Science.gov (United States)

Huang, Zufeng; Miao, Xiaoqing

2015-09-01

To investigate the effect of non-phacoemulsification cataract operation in two different patterns of nucleus delivery on the quantity and morphology of corneal endothelial cells and postoperative visual acuity. Forty patients diagnosed with cataract underwent cataract surgery and were assigned into the direct nuclear delivery and semi-nuclear delivery groups. Lens density was measured and divided into the hard and soft lenses according to Emery-little lens nucleus grading system. Non-phacoemulsification cataract operation was performed. At 3 d after surgery, the quantity and morphology of corneal endothelium were counted and observed under corneal endothelial microscope. During 3-month postoperative follow-up, the endothelial cell loss rate, morphological changes and visual acuity were compared among four groups. Corneal endothelial cell loss rate in the direct delivery of hard nucleus group significantly differed from those in the other three groups before and 3 months after operation (P nucleus, semi-delivery of hard nucleus and semi-delivery soft nucleus groups (all P > 0.05). Preoperative and postoperative 2-d visual acuity did not differ between the semi-delivery of hard nucleus and direct delivery of soft nucleus groups (P = 0.49), significantly differed from those in the semi-delivery of soft nucleus (P = 0.03) and direct delivery of hard nucleus groups (P = 0.14). Visual acuity at postoperative four months did not differ among four groups (P = 0.067). During non-phacoemulsification cataract surgery, direct delivery of hard nucleus caused severe injury to corneal endothelium and semi-delivery of soft nucleus yielded mild corneal endothelial injury. Slight corneal endothelial injury exerted no apparent effect upon visual acuity and corneal endothelial morphology at three months after surgery.

300 Area treated effluent disposal facility operating specifications document

International Nuclear Information System (INIS)

Olander, A.R.

1994-01-01

These specifications deal with the release of treated water into the Columbia River via the TEDF submerged outfall. Specific limits are set for contaminants to be discharged in NPDES permit WA-002591-7. This section contains the operating ranges that will be used to best meet the permit limits

Non-standard quantum groups and superization

Energy Technology Data Exchange (ETDEWEB)

Majid, S. [Cambridge Univ. (United Kingdom). Dept. of Applied Mathematics and Theoretical Physics (DAMTP); Rodriguez-Plaza, M.J. [Nationaal Inst. voor Kernfysica en Hoge-Energiefysica (NIKHEF), Amsterdam (Netherlands). Sectie H

1995-12-31

We obtain the universal R-matrix of the non-standard quantum group associated to the Alexander-Conway knot polynomial. We show further that this nonstandard quantum group is related to the super-quantum group U{sub q}gl(1 vertical stroke 1) by a general process of superization, which we describe. We also study a twisted variant of this non-standard quantum group and obtain, as a result, a twisted version uf U{sub q}gl(1 vertical stroke 1) as a q-supersymmetry of the exterior differential calculus of any quantum plane of Hecke type, acting by mixing the bosonic x{sub i} co-ordinates and the forms dx{sub i}. (orig.).

Condition Monitoring of Machinery in Non-Stationary Operations : Proceedings of the Second International Conference "Condition Monitoring of Machinery in Non-Stationnary Operations"

CERN Document Server

Bartelmus, Walter; Chaari, Fakher; Zimroz, Radoslaw; Haddar, Mohamed

2012-01-01

Condition monitoring of machines in non-stationary operations (CMMNO) can be seen as the major challenge for research in the field of machinery diagnostics. Condition monitoring of machines in non-stationary operations is the title of the presented book and the title of the Conference held in Hammamet - Tunisia March 26 – 28, 2012. It is the second conference under this title, first took place in Wroclaw - Poland , March 2011. The subject CMMNO comes directly from industry needs and observation of real objects. Most monitored and diagnosed objects used in industry works in non-stationary operations condition. The non-stationary operations come from fulfillment of machinery tasks, for which they are designed for. All machinery used in different kind of mines, transport systems, vehicles like: cars, buses etc, helicopters, ships and battleships and so on work in non-stationary operations. The papers included in the book are shaped by the organizing board of the conference and authors of the papers. The papers...

Evaluation of prognostic differences in elderly patients with pneumonia treated by between pulmonologists and non-pulmonologists: a propensity score analysis.

Science.gov (United States)

Komiya, Kosaku; Oka, Hiroaki; Ohama, Minoru; Uchida, Masahiro; Miyajima, Hajime; Iwashita, Tomohiko; Okabe, Eiji; Shuto, Osamu; Matsumoto, Taisuke; Ishii, Hiroshi; Kadota, Jun-Ichi

2016-07-01

The incidence of pneumonia among elderly people is increasing in aged countries, and both pulmonologists and non-pulmonologists treat such patients. The aim of this study was to assess prognostic differences between elderly patients treated by pulmonologists and those treated by non-pulmonologists. This study was a retrospective cohort using a propensity score analysis. Patients 65 years of age or over with pneumonia were consecutively included. The propensity score was estimated based on the patient's background and severity of pneumonia. The difference in 30-day and 90-day mortality depending on the attending physician's specialty was analyzed after adjusting for other variables, including the propensity score. We assessed 68 and 182 patients treated by pulmonologists and non-pulmonologists, respectively. The pulmonologists tended to be in charge of patients with hypoxemia, chronic obstructive pulmonary disease or dementia without aspiration pneumonia or renal dysfunction (area under receiver operating characteristic curve to predict treatment by a pulmonologist according to the propensity score = 0.737, P bedridden status (3.000, P = 0.013) and the serum albumin level (0.382, P elderly patients may not necessarily improve, irrespective of treatment by pulmonologists, and host factors seemed to be associated with mortality. © 2014 John Wiley & Sons Ltd.

A Novel Therapeutic Frame for Treating Depression in Group Treating Depression Downhill

Directory of Open Access Journals (Sweden)

Valery Krupnik

2014-02-01

Full Text Available We describe an original protocol Treating Depression Downhill (TDD that was designed as a specific therapy for depression. Evolutionary theories of depression served as a basis for its development. We discuss the rationale for using evolutionary theory and describe the structure and integrative nature of TDD. We then present an observation on TDD’s application to group therapy of active duty military personnel. In the described sample, TDD demonstrated effectiveness and specificity for depression, differentiating it from anxiety and personality disorders.

75 FR 47631 - Swets Information Services, Operations Department, Information Technology Group, Marketing Group...

Science.gov (United States)

2010-08-06

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-73,668] Swets Information Services, Operations Department, Information Technology Group, Marketing Group, Finance Group, Runnemede..., Information Technology (IT) Group, Marketing Group and the Finance Group into one entity instead of...

A non-destructive approach for assessing decay in preservative treated wood

NARCIS (Netherlands)

Machek, L.; Edlund, M.L.; Sierra-Alvarez, R.; Militz, H.

2004-01-01

This study investigated the suitability of the non-destructive vibration-impulse excitation technique to assess the attack of preservative-treated wood in contact with the ground. Small stakes (10×5×100 mm3) of treated and untreated Scots pine sapwood were exposed to decay in laboratory-scale

Erlotinib in previously treated non-small-cell lung cancer

International Nuclear Information System (INIS)

Smrdel, U.; Kovac, V.

2006-01-01

Background. Erlotinib is a novel biological anti-tumour agent in the treatment of advanced non small cell lung cancer. It represents the molecularly-targeted therapy which has been studied extensively. Case report. We present a case of a patient who suffered from advanced non-small-cell lung cancer. After the progress of disease following a prior chemotherapy he was treated with erlotinib with remarkable effect which was shown at chest x ray and symptoms were quite reduced. Conclusions. In selected patients with advanced non-small-cell lung cancer Erlotinib improves survival and symptom control as it results in presented case. (author)

47 CFR 90.233 - Base/mobile non-voice operations.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false Base/mobile non-voice operations. 90.233... SERVICES PRIVATE LAND MOBILE RADIO SERVICES Non-Voice and Other Specialized Operations § 90.233 Base/mobile non-voice operations. The use of A1D, A2D, F1D, F2D, G1D, or G2D emission may be authorized to base...

Some aspects of non-linear semi-groups

International Nuclear Information System (INIS)

Plant, A.T.

1976-01-01

Some simpler theorems in the theory of non-linear semi-groups of non-reflexive Banach spaces are proved, with the intention to introduce the reader to this active field of research. Flow invariance, in particular for Lipschitz generators, and contraction semi-groups are discussed in some detail. (author)

A randomised control trial on the use of topical methicillin in reducing post-operative ventriculoperitoneal shunt infection.

Science.gov (United States)

Theophilus, Sharon Casilda; Adnan, Johari Siregar

2011-01-01

A double-blind randomised control study was conducted on all patients who were admitted or referred to the Department of Neurosurgery, Sultanah Aminah Hospital, Johor Bahru, with a diagnosis of hydrocephalus where a ventriculoperitoneal shunt was indicated. The period of study was from November 2005 to May 2007, and the follow-up period was 3 months after surgery. Randomisation was carried out in the operating room prior to the procedure. The scrub nurse selected a sealed envelope, which contained the assignment of each patient to 1 of 2 treatment groups: Group 1 patients were treated with topical methicillin, and Group 2 patients were not treated with topical methicillin. Prophylactic antibiotic, cefuroxime (25 mg/kg) was given intravenously at induction. Standard sterile operative technique was followed in preparing and draping the patients. A total of 90 patients were recruited in the study, and 13 (14.4%) patients developed an infection within 3 months post-operation. Group 1 had a 8.9% risk of infection, and Group 2 had a 20% risk; however, there was no statistically significant post-operative ventriculoperitoneal shunt (VPS) infection reduction with the use of topical methicillin in VPS surgery (P = 0.230). Multivariate analysis showed that only duration of surgery had a significant influence on the incidence of post-operative VPS infection in the non-methicillin group (P = 0.02). The non-methicillin group had an 8 times greater risk of developing post-operative VPS infection than the methicillin group if surgery lasted longer than 1 hour. Topical methicillin had no significance in the reduction of post-operative VPS infection.

Integrated versus non-integrated orbital implants for treating anophthalmic sockets.

Science.gov (United States)

Schellini, Silvana; El Dib, Regina; Silva, Leandro Re; Farat, Joyce G; Zhang, Yuqing; Jorge, Eliane C

2016-11-07

, 95% CI 1.01 to 2.91) or PMMA with myoconjunctival enucleation (-0.57 mm, 95% CI -1.63 to 0.49). Similarly, for vertical implant motility, there was very low-certainty evidence of a difference in the comparison of PP to PMMA traditional (MD 3.12 mm 95% CI 2.36 to 3.88) but no evidence of a difference when comparing PP to PMMA myoconjunctival (MD -0.20 mm 95% CI -1.28 to 0.88). Four people in the PP group (total N = 50) experienced adverse events (i.e. exposures) compared to 6/100 in the PMMA groups (RR 17.82, 95% CI 0.98 to 324.67, N = 150, very low-certainty evidence).None of the studies reported socket sphere size, cosmetic effect or quality of life measures. Current very low-certainty evidence from three small published randomised controlled trials did not provide sufficient evidence to assess the effect of integrated and non-integrated material orbital implants for treating anophthalmic sockets. This review underlines the need to conduct further well-designed trials in this field.

A non-perturbative operator product expansion

International Nuclear Information System (INIS)

Bietenholz, W.; Cundy, N.; Goeckeler, M.

2009-10-01

Nucleon structure functions can be observed in Deep Inelastic Scattering experiments, but it is an outstanding challenge to confront them with fully non-perturbative QCD results. For this purpose we investigate the product of electromagnetic currents (with large photonmomenta) between quark states (of low momenta). By means of an Operator Product Expansion the structure function can be decomposed into matrix elements of local operators, and Wilson coefficients. For consistency both have to be computed non-perturbatively. Here we present precision results for a set of Wilson coefficients. They are evaluated from propagators for numerous quark momenta on the lattice, where the use of chiral fermions suppresses undesired operator mixing. This overdetermines the Wilson coefficients, but reliable results can be extracted by means of a Singular Value Decomposition. (orig.)

Development and External Validation of Prognostic Model for 2-Year Survival of Non-Small-Cell Lung Cancer Patients Treated With Chemoradiotherapy

International Nuclear Information System (INIS)

Dehing-Oberije, Cary; Yu Shipeng; De Ruysscher, Dirk; Meersschout, Sabine; Van Beek, Karen; Lievens, Yolande; Van Meerbeeck, Jan; De Neve, Wilfried; Rao, Bharat Ph.D.; Weide, Hiska van der; Lambin, Philippe

2009-01-01

Purpose: Radiotherapy, combined with chemotherapy, is the treatment of choice for a large group of non-small-cell lung cancer (NSCLC) patients. Recent developments in the treatment of these patients have led to improved survival. However, the clinical TNM stage is highly inaccurate for the prediction of survival, and alternatives are lacking. The objective of this study was to develop and validate a prediction model for survival of NSCLC patients, treated with chemoradiotherapy. Patients and Methods: The clinical data from 377 consecutive inoperable NSCLC patients, Stage I-IIIB, treated radically with chemoradiotherapy were collected. A prognostic model for 2-year survival was developed, using 2-norm support vector machines. The performance of the model was expressed as the area under the curve of the receiver operating characteristic and assessed using leave-one-out cross-validation, as well as two external data sets. Results: The final multivariate model consisted of gender, World Health Organization performance status, forced expiratory volume in 1 s, number of positive lymph node stations, and gross tumor volume. The area under the curve, assessed by leave-one-out cross-validation, was 0.74, and application of the model to the external data sets yielded an area under the curve of 0.75 and 0.76. A high- and low-risk group could be clearly identified using a risk score based on the model. Conclusion: The multivariate model performed very well and was able to accurately predict the 2-year survival of NSCLC patients treated with chemoradiotherapy. The model could support clinicians in the treatment decision-making process.

Operation of the Selected Local Action Group

Directory of Open Access Journals (Sweden)

Lukáš Nevěděl

2015-01-01

Full Text Available The main objective of this article is to compare the current operation of elected local action group with the concept of learning regions. This comparison is built on detailed knowledge and understanding of the operation of local action group Podbrnensko citizens’ association (Podbrnensko CA and learning regions in general. The following is assumed: the understanding of community-based processes from the perspective of residents, the important stakeholders who influence the operation of communities or locations. The operation of local action groups is in line with the current concept led by local community development (community led local development, CLLD, which uses elements of the LEADER method. In this method the solution of development problems comes primarily from the inside, not from the outside of the studied territory. The methods used for the collection of empirical data were mostly observation and interviews with all partners involved in LAG (31 people, all mayors in LAG (29 people and 176 people from region, i.e. methods, which result in so called deep data. Between the primary techniques applied in the research are: participant observation, unstructured or semi-structured interviews and public debates.

A fast non-Fourier method for Landau-fluid operators

Energy Technology Data Exchange (ETDEWEB)

Dimits, A. M., E-mail: dimits1@llnl.gov; Joseph, I.; Umansky, M. V. [Lawrence Livermore National Laboratory, L-637, P.O. Box 808, Livermore, California 94511-0808 (United States)

2014-05-15

An efficient and versatile non-Fourier method for the computation of Landau-fluid (LF) closure operators [Hammett and Perkins, Phys. Rev. Lett. 64, 3019 (1990)] is presented, based on an approximation by a sum of modified-Helmholtz-equation solves (SMHS) in configuration space. This method can yield fast-Fourier-like scaling of the computational time requirements and also provides a very compact data representation of these operators, even for plasmas with large spatial nonuniformity. As a result, the method can give significant savings compared with direct application of “delocalization kernels” [e.g., Schurtz et al., Phys. Plasmas 7, 4238 (2000)], both in terms of computational cost and memory requirements. The method is of interest for the implementation of Landau-fluid models in situations where the spatial nonuniformity, particular geometry, or boundary conditions render a Fourier implementation difficult or impossible. Systematic procedures have been developed to optimize the resulting operators for accuracy and computational cost. The four-moment Landau-fluid model of Hammett and Perkins has been implemented in the BOUT++ code using the SMHS method for LF closure. Excellent agreement has been obtained for the one-dimensional plasma density response function between driven initial-value calculations using this BOUT++ implementation and matrix eigenvalue calculations using both Fourier and SMHS non-Fourier implementations of the LF closures. The SMHS method also forms the basis for the implementation, which has been carried out in the BOUT++ code, of the parallel and toroidal drift-resonance LF closures. The method is a key enabling tool for the extension of gyro-Landau-fluid models [e.g., Beer and Hammett, Phys. Plasmas 3, 4046 (1996)] to codes that treat regions with strong profile variation, such as the tokamak edge and scrapeoff-layer.

The group theory of oxidation II: cosets of non-split groups

International Nuclear Information System (INIS)

Keurentjes, Arjan

2003-01-01

The oxidation program given in the first article of this series (see preceding article in this issue) is extended to cover oxidation of 3d sigma model theories on a coset G/H, with G non-compact (but not necessarily split), and H the maximal compact subgroup. We recover the matter content, the equations of motion and Bianchi identities from group lattice and Cartan involution. Satake diagrams provide an elegant tool for the computations, the maximal oxidation dimension, and group disintegration chains can be directly read off. We give a complete list of theories that can be recovered from oxidation of a 3-dimensional coset sigma model on G/H, where G is a simple non-compact group

A Randomised Control Trial on the Use of Topical Methicillin in Reducing Post-Operative Ventriculoperitoneal Shunt Infection

Science.gov (United States)

Theophilus, Sharon Casilda; Adnan, Johari Siregar

2011-01-01

Background: A double-blind randomised control study was conducted on all patients who were admitted or referred to the Department of Neurosurgery, Sultanah Aminah Hospital, Johor Bahru, with a diagnosis of hydrocephalus where a ventriculoperitoneal shunt was indicated. Methods: The period of study was from November 2005 to May 2007, and the follow-up period was 3 months after surgery. Randomisation was carried out in the operating room prior to the procedure. The scrub nurse selected a sealed envelope, which contained the assignment of each patient to 1 of 2 treatment groups: Group 1 patients were treated with topical methicillin, and Group 2 patients were not treated with topical methicillin. Prophylactic antibiotic, cefuroxime (25 mg/kg) was given intravenously at induction. Standard sterile operative technique was followed in preparing and draping the patients. Results: A total of 90 patients were recruited in the study, and 13 (14.4%) patients developed an infection within 3 months post-operation. Group 1 had a 8.9% risk of infection, and Group 2 had a 20% risk; however, there was no statistically significant post-operative ventriculoperitoneal shunt (VPS) infection reduction with the use of topical methicillin in VPS surgery (P = 0.230). Multivariate analysis showed that only duration of surgery had a significant influence on the incidence of post-operative VPS infection in the non-methicillin group (P = 0.02). The non-methicillin group had an 8 times greater risk of developing post-operative VPS infection than the methicillin group if surgery lasted longer than 1 hour. Conclusion: Topical methicillin had no significance in the reduction of post-operative VPS infection. PMID:22135571

Risk Factors for the Failure of Spinal Burst Fractures Treated Conservatively According to the Thoracolumbar Injury Classification and Severity Score (TLICS: A Retrospective Cohort Trial.

Directory of Open Access Journals (Sweden)

Jieliang Shen

Full Text Available The management of thoracolumbar (TL burst fractures is still controversial. The thoracolumbar injury classification and severity score (TLICS algorithm is now widely used to guide clinical decision making, however, in clinical practice, we come to realize that TLICS also has its limitations for treating patients with total scores less than 4, for which conservative treatment may not be optimal in all cases.The aim of this study is to identify several risk factors for the failure of conservative treatment of TL burst fractures according to TLICS algorithm.From June 2008 to December 2013, a cohort of 129 patients with T10-l2 TL burst fractures with a TLISC score ≤3 treated non-operatively were identified and included into this retrospective study. Age, sex, pain intensity, interpedicular distance (IPD, canal compromise, loss of vertebral body height and kyphotic angle (KA were selected as potential risk factors and compared between the non-operative success group and the non-operative failure group.One hundred and four patients successfully completed non-operative treatment, the other 25 patients were converted to surgical treatment because of persistent local back pain or progressive neurological deficits during follow-up. Our results showed that age, visual analogue scale (VAS score and IPD, KA were significantly different between the two groups. Furthermore, regression analysis indicated that VAS score and IPD could be considered as significant predictors for the failure of conservative treatment.The recommendation of non-operative treatment for TLICS score ≤3 has limitations in some patients, and VAS score and IPD could be considered as risk factors for the failure of conservative treatment. Thus, conservative treatment should be decided with caution in patients with greater VAS scores or IPD. If non-operative management is decided, a close follow-up is necessary.

Outcome of non-operative management of femoral shaft fractures in children

Directory of Open Access Journals (Sweden)

Akinyoola A

2011-01-01

Full Text Available Background: Femoral shaft fractures are common injuries in childhood. There is paucity of information on their presentation and outcome of the available treatment methods in the African population. This study evaluated the outcome of non-operative methods of treatment of femoral shaft fractures in our centre. Patients and Methods: A retrospective review of the database of children aged 14 years and below with femoral shaft fractures treated non-operatively over a 10-year period. Results: A total of 134 patients with 138 fractures met the study criteria. This consisted of 71 boys (mean age = 6.1 years ± SD and 63 girls (mean age = 6.5 years ± SD. Pedestrian vehicular accident was the most common cause of femoral shaft fractures in the study population. The midshaft was the most common site of fractures. There were associated injuries to other parts of the body (especially head injury in 34.3% of the patients. The commonest mode of treatment was skin traction only (87.7%. The mean time to fracture union was 4.9 weeks ± SD (range = 3-15 weeks. The mean length of hospitalisation was 6.7 weeks ± SD (range = 5 days-11 weeks. There was a fairly strong positive correlation between the length of hospitalisation and the presence of associated injuries, especially head injury, upper limb fractures and bilaterality of the fractures. The mean total cost of treatment was #7685 (Naira or $51.2 (range = $14.2-$190. At the last follow up, 97.8% of the fractures united without significant angulation or shortening. Conclusion: The outcome of non-operative treatment of femoral shaft fractures in our setting is comparable to the results of other workers. Methods of treatment that shorten the length of hospitalisation without unduly increasing cost should be encouraged.

Operant Reinforcement with Structural Family Therapy in Treating Anorexia Nervosa

Science.gov (United States)

Perlman, Lawrence M.; Bender, Sheila S.

1975-01-01

The authors successfully treated two families in which the index patients were anorectic adolescent girls by combining structural family therapy with behavioral modification techniques. Phases which appear to be typical of the treatment are described. A discussion of the value of the operant reinforcement procedure in family therapy follows.…

Articular congruity is associated with short-term clinical outcomes of operatively treated SER IV ankle fractures.

Science.gov (United States)

Berkes, Marschall B; Little, Milton T M; Lazaro, Lionel E; Pardee, Nadine C; Schottel, Patrick C; Helfet, David L; Lorich, Dean G

2013-10-02

With regard to supination-external rotation type-IV (SER IV) ankle fractures, there is no consensus regarding which patient, injury, and treatment variables most strongly influence clinical outcome. The purpose of this investigation was to examine the impact of articular surface congruity on the functional outcomes of operatively treatment of SER IV ankle fractures. A prospectively generated database consisting of operatively treated SER IV ankle fractures was reviewed. Postoperative computed tomography (CT) scans were used to assess ankle joint congruity. Ankles were considered incongruent in the presence of >2 mm of articular step-off, intra-articular loose bodies, or an articular surface gap of >2 mm (despite an otherwise anatomic reduction) due to joint impaction and comminution. Patients with at least one year of clinical follow-up were eligible for analysis. The primary and secondary outcome measures were the Foot and Ankle Outcome Score (FAOS) and ankle motion. One hundred and eight SER IV fractures met our inclusion criteria. The average duration of follow-up was twenty-one months. Seventy-two patients (67%) had a congruent ankle joint, and thirty-six (33%) had elements of articular surface incongruity on postoperative CT scanning. These two groups were similar with regard to comorbidities and injury and treatment variables. At the time of the final follow-up, the group with articular incongruity had a significantly worse FAOS with regard to symptoms (p = 0.012), pain (p = 0.004), and activities of daily living (p = 0.038). Those with articular incongruity had worse average scores in the FAOS sport domain as well. No significant differences in ankle motion were found between the two groups. In this population of patients with an operatively treated SER IV ankle fracture, the presence of postoperative articular incongruity correlated with inferior early clinical outcomes. Orthopaedic surgeons should scrutinize ankle fracture reductions and strive for

Non-operative management (NOM) of blunt hepatic trauma: 80 cases.

Science.gov (United States)

Özoğul, Bünyami; Kısaoğlu, Abdullah; Aydınlı, Bülent; Öztürk, Gürkan; Bayramoğlu, Atıf; Sarıtemur, Murat; Aköz, Ayhan; Bulut, Özgür Hakan; Atamanalp, Sabri Selçuk

2014-03-01

Liver is the most frequently injured organ upon abdominal trauma. We present a group of patients with blunt hepatic trauma who were managed without any invasive diagnostic tools and/or surgical intervention. A total of 80 patients with blunt liver injury who were hospitalized to the general surgery clinic or other clinics due to the concomitant injuries were followed non-operatively. The normally distributed numeric variables were evaluated by Student's t-test or one way analysis of variance, while non-normally distributed variables were analyzed by Mann-Whitney U-test or Kruskal-Wallis variance analysis. Chi-square test was also employed for the comparison of categorical variables. Statistical significance was assumed for phepatic trauma seems to be the gold standard.

200 Area Treated Effluent Disposal Facility operational test specification. Revision 2

International Nuclear Information System (INIS)

Crane, A.F.

1995-01-01

This document identifies the test specification and test requirements for the 200 Area Treated Effluent Disposal Facility (200 Area TEDF) operational testing activities. These operational testing activities, when completed, demonstrate the functional, operational and design requirements of the 200 Area TEDF have been met. The technical requirements for operational testing of the 200 Area TEDF are defined by the test requirements presented in Appendix A. These test requirements demonstrate the following: pump station No.1 and associated support equipment operate both automatically and manually; pump station No. 2 and associated support equipment operate both automatically and manually; water is transported through the collection and transfer lines to the disposal ponds with no detectable leakage; the disposal ponds accept flow from the transfer lines with all support equipment operating as designed; and the control systems operate and status the 200 Area TEDF including monitoring of appropriate generator discharge parameters

Supporting CANDU operators-CANDU owners group

International Nuclear Information System (INIS)

Collingwood, B.R.

1997-01-01

The CANDU Owners Group (COG) was formed in 1984 by the Canadian CANDU owning utilities and Atomic Energy of Canada limited (AECL). Participation was subsequently extended to all CANDU owners world-wide. The mandate of the COG organization is to provide a framework for co-operation, mutual assistance and exchange of information for the successful support, development, operation, maintenance and economics of CANDU nuclear electric generating stations. To meet these objectives COG established co-operative programs in two areas: 1. Station Support. 2. Research and Development. In addition, joint projects are administered by COG on a case by case basis where CANDU owners can benefit from sharing of costs

Operation of heavily irradiated silicon detectors in non-depletion mode

International Nuclear Information System (INIS)

Verbitskaya, E.; Eremin, V.; Ilyashenko, I.; Li, Z.; Haerkoenen, J.; Tuovinen, E.; Luukka, P.

2006-01-01

The non-depletion detector operation mode has generally been disregarded as an option in high-energy physics experiments. In this paper, the non-depletion operation is examined by detailed analysis of the electric field distribution and the current pulse response of heavily irradiated silicon (Si) detectors. The previously reported model of double junction in heavily irradiated Si detector is further developed and a simulation of the current pulse response has been performed. It is shown that detectors can operate in a non-depletion mode due to the fact that the value of the electric field in a non-depleted region is high enough for efficient carrier drift. This electric field originates from the current flow through the detector and a consequent drop of the potential across high-resistivity bulk of a non-depleted region. It is anticipated that the electric field in a non-depleted region, which is still electrically neutral, increases with fluence that improves the non-depleted detector operation. Consideration of the electric field in a non-depleted region allows the explanation of the recorded double-peak current pulse shape of heavily irradiated Si detectors and definition of the requirements for the detector operational conditions. Detailed reconstruction of the electric field distribution gives new information on radiation effects in Si detectors

Finite Groups with Given Quantitative Non-Nilpotent Subgroups II

DEFF Research Database (Denmark)

Shi, Jiangtao; Zhang, Cui

2014-01-01

As an extension of Shi and Zhang's 2011 article [4], we prove that any finite group having at most 23 non-normal non-nilpotent proper subgroups is solvable except for G ≅ A 5 or SL(2, 5), and any finite group having at most three conjugacy classes of non-normal non-nilpotent proper subgroups is s...

Research on Group Operation Mode of Once-through Steam Generator

International Nuclear Information System (INIS)

Hao, Cheng Ming; Liu, Xinkai; Peng, Min Jun; Xia, Genglei

2011-01-01

Integrated Pressurized Water Reactor (IPWR) owns more than one once-through steam generators (OTSGs). Flow instability may occur in secondary side of OTSG under certain conditions. Trying to avoid the occurrence of flow instability is of great important for the safe and stable operation of OTSG. Because of the fact that flow instability often occurs in certain regions, so when OTSGs operate with low load, OTSGs can be separated into several groups, which can avoid flow instability. In this paper, operational characteristics of IPWR are analyzed by RELAP5/MOD3.4 code and during the discussion of group operation, a rapid change load operation scheme using OTSG group operation mode which can be used in IPWR is proposed

Research on Group Operation Mode of Once-through Steam Generator

Energy Technology Data Exchange (ETDEWEB)

Hao, Cheng Ming; Liu, Xinkai; Peng, Min Jun; Xia, Genglei [Harbin Engineering University, Harbin (China)

2011-08-15

Integrated Pressurized Water Reactor (IPWR) owns more than one once-through steam generators (OTSGs). Flow instability may occur in secondary side of OTSG under certain conditions. Trying to avoid the occurrence of flow instability is of great important for the safe and stable operation of OTSG. Because of the fact that flow instability often occurs in certain regions, so when OTSGs operate with low load, OTSGs can be separated into several groups, which can avoid flow instability. In this paper, operational characteristics of IPWR are analyzed by RELAP5/MOD3.4 code and during the discussion of group operation, a rapid change load operation scheme using OTSG group operation mode which can be used in IPWR is proposed.

Unit operations used to treat process and/or waste streams at nuclear power plants

International Nuclear Information System (INIS)

Godbee, H.W.; Kibbey, A.H.

1980-01-01

Estimates are given of the annual amounts of each generic type of LLW [i.e., Government and commerical (fuel cycle and non-fuel cycle)] that is generated at LWR plants. Many different chemical engineering unit operations used to treat process and/or waste streams at LWR plants include adsorption, evaporation, calcination, centrifugation, compaction, crystallization, drying, filtration, incineration, reverse osmosis, and solidification of waste residues. The treatment of these various streams and the secondary wet solid wastes thus generated is described. The various treatment options for concentrates or solid wet wastes, and for dry wastes are discussed. Among the dry waste treatment methods are compaction, baling, and incineration, as well as chopping, cutting and shredding. Organic materials [liquids (e.g., oils or solvents) and/or solids], could be incinerated in most cases. The filter sludges, spent resins, and concentrated liquids (e.g., evaporator concentrates) are usually solidified in cement, or urea-formaldehyde or unsaturated polyester resins prior to burial. Incinerator ashes can also be incorporated in these binding agents. Asphalt has not yet been used. This paper presents a brief survey of operational experience at LWRs with various unit operations, including a short discussion of problems and some observations on recent trends

Operation for recurrent cystocele with anterior colporrhaphy or non-absorbable mesh: patient reported outcomes

DEFF Research Database (Denmark)

Nüssler, Emil Karl; Greisen, Susanne; Kesmodel, Ulrik Schiøler

2013-01-01

Abstract INTRODUCTION AND HYPOTHESIS: The aim of this study was to compare patient reported outcomes and complications after repair of recurrent anterior vaginal wall prolapse in routine health care settings using standard anterior colporrhaphy or non-absorbable mesh. METHODS: The study is based...... on prospective data from the Swedish National Register for Gynaecological Surgery. 286 women were operated on for recurrent anterior vaginal wall prolapse in 2008-2010; 157 women had an anterior colporrhaphy and 129 were operated on with a non-absorbable mesh. Pre-, and perioperative data were collected from...... (0.6 %) in the anterior colporrhaphy group (p = 0.58). The infection rate was higher after mesh (8.5 %) than after anterior colporrhaphy (2.5 %; OR 3.19 ; 1.07-14.25). CONCLUSION: Implantation of synthetic mesh during operation for recurrent cystocele more than doubled the cure rate, whereas...

Non-operative management of perforated peptic ulcer

International Nuclear Information System (INIS)

Rahman, M.M.; Ahsan, H.N.; Hossain, M.D.

2003-01-01

Objective: The aim of this study was to see the morbidity and mortality in peptic ulcer perforation cases by non-operative management in selected cases. Results: In the selected 54 patients, male: female were 49:05. Nine had history of NSAID intake. There was no mortality. Morbidity analysis showed that three had hepatic abscess, four had pelvic abscess, six took prolonged time for improvement, in two cases conservative treatment had to be abandoned and laparotomy was done in the same hospital admission. Conclusion: Non-operative procedure is a safe and effective measure for the management of perforated peptic ulcer in selected cases. (author)

An assessment of the quality indicators of operative and non-operative times in a public university hospital.

Science.gov (United States)

Costa, Altair da Silva; Leão, Luiz Eduardo Villaça; Novais, Maykon Anderson Pires de; Zucchi, Paola

2015-01-01

To assess the operative time indicators in a public university hospital. A descriptive cross-sectional study was conducted using data from operating room database. The sample was obtained from January 2011 to January 2012. The operations performed in sequence in the same operating room, between 7:00 am and 5:00 pm, elective or emergency, were included. The procedures with incomplete data in the system were excluded, as well as the operations performed after 5:00 pm or on weekends or holidays. We measured the operative and non-operative time of 8,420 operations. The operative time (mean and standard deviation) of anesthesias and operations were 177.6 ± 110 and 129.8 ± 97.1 minutes, respectively. The total time of the patient in operative room (mean and standard deviation) was 196.8 ± 113.2. The non-operative time, e.g., between the arrival of the patient and the onset of anesthesia was 14.3 ± 17.3 minutes. The time to set the next patient in operating room was 119.8 ± 79.6 minutes. Our total non-operative time was 155 minutes. Delays frequently occurred in our operating room and had a major effect on patient flow and resource utilization. The non-operative time was longer than the operative time. It is possible to increase the operating room capacity by management and training of the professionals involved. The indicators provided a tool to improve operating room efficiency.

Bosonic construction of the Lie algebras of some non-compact groups appearing in supergravity theories and their oscillator-like unitary representations

International Nuclear Information System (INIS)

Guenaydin, M.; Saclioglu, C.

1981-06-01

We give a construction of the Lie algebras of the non-compact groups appearing in four dimensional supergravity theories in terms of boson operators. Our construction parallels very closely their emergence in supergravity and is an extension of the well-known construction of the Lie algebras of the non-compact groups Sp(2n,IR) and SO(2n) from boson operators transforming like a fundamental representation of their maximal compact subgroup U(n). However this extension is non-trivial only for n >= 4 and stops at n = 8 leading to the Lie algebras of SU(4) x SU(1,1), SU(5,1), SO(12) and Esub(7(7)). We then give a general construction of an infinite class of unitary irreducible representations of the respective non-compact groups (except for Esub(7(7)) and SO(12) obtained from the extended construction). We illustrate our construction with the examples of SU(5,1) and SO(12). (orig.)

Linearization of non-commuting operators in the partition function

International Nuclear Information System (INIS)

Ahmed, M.

1983-06-01

A generalization of the Stratonovich-Hubbard scheme for evaluating the grand canonical partition function is given. The scheme involves linearization of products of non-commuting operators using the functional integral method. The non-commutivity of the operators leads to an additional term which can be absorbed in the single-particle Hamiltonian. (author)

Proinflammatory and anti-inflammatory cytokines present in the acute phase of experimental colitis treated with Saccharomyces boulardii.

Science.gov (United States)

Grijó, Nathália Nahas; Borra, Ricardo Carneiro; Sdepanian, Vera Lucia

2010-09-01

To study the proinflammatory and anti-inflammatory cytokines present in the acute phase of trinitrobenzene sulfonic acid (TNBS)-induced experimental colitis treated with Saccharomyces boulardii. Thirty male Wistar rats were divided into three groups: (1) treated group--received Saccharomyces boulardii for 14 days; (2) non-treated group--received sodium chloride solution for 14 days; (3) control group. Colitis was induced on the seventh day of the study in the treated and the non-treated groups using TNBS (10 mg) dissolved in 50% ethanol. Quantification of cytokines, including interleukin (IL)-1beta (IL-1beta), IL-6, transforming growth factor-beta (TGF-beta), IL-10 and tumor necrosis factor-alpha (TNF-alpha), in the serum and colonic tissue collected on day 14 were carried out using an enzyme-linked immunosorbent assay (ELISA). The mean concentrations of TGF-beta in both the serum and the colonic tissue of the treated group were statistically higher than that of the control group. The mean concentration of TGF-beta in the colonic tissue of the non-treated group was also statistically higher than the control group. The group treated with Saccharomyces boulardii showed increased amounts of TGF-beta, an anti-inflammatory cytokine, during the acute phase of colitis. There were no differences in the amount of TNF-alpha, IL-1beta, IL-6, and IL-10 between the treated and the non-treated or the control groups during the acute phase of experimental colitis induced by TNBS.

Process Analysis of the CV Group's Operation

CERN Document Server

Wilhelmsson, M

2000-01-01

This report will give an explanation of the internal reorganization that has been done because of the necessity to optimize operation in the cooling and ventilation group. The basic structure for the group was defined at the end of 1998. We understood then that change was needed to accommodate the increased workload due to the LHC project. In addition, we face a relatively large turnover of personnel (retirements and some recruitment) with related integration issues to consider. We would also like to implement new approaches in the management of both operations and maintenance. After some running-in problems during the first half of 1999, we realized that much more could be gained with the analysis and the definition and documenting of each single function and generic activity within the group. The authors will explain how this analysis was carried out and give some feedback of the outcome, so far.

Development of the Operational Events Groups Ranking Tool

International Nuclear Information System (INIS)

Simic, Zdenko; Banov, Reni

2014-01-01

Both because of complexity and ageing, facilities like nuclear power plants require feedback from the operating experience in order to further improve safety and operation performance. That is the reason why significant effort is dedicated to operating experience feedback. This paper contains description of the specification and development of the application for the operating events ranking software tool. Robust and consistent way of selecting most important events for detail investigation is important because it is not feasible or even useful to investigate all of them. Development of the tool is based on the comprehensive events characterisation and methodical prioritization. This includes rich set of events parameters which allow their top level preliminary analysis, different ways of groupings and even to evaluate uncertainty propagation to the ranking results. One distinct feature of the implemented method is that user (i.e., expert) could determine how important is particular ranking parameter based on their pairwise comparison. For tools demonstration and usability it is crucial that sample database is also created. For useful analysis the whole set of events for 5 years is selected and characterised. Based on the preliminary results this tool seems valuable for new preliminary prospective on data as whole, and especially for the identification of events groups which should have priority in the more detailed assessment. The results are consisting of different informative views on the events groups importance and related sensitivity and uncertainty results. This presents valuable tool for improving overall picture about specific operating experience and also for helping identify the most important events groups for further assessment. It is clear that completeness and consistency of the input data characterisation is very important to get full and valuable importance ranking. Method and tool development described in this paper is part of continuous effort of

Diagonalizing quadratic bosonic operators by non-autonomous flow equations

CERN Document Server

Bach, Volker

2016-01-01

The authors study a non-autonomous, non-linear evolution equation on the space of operators on a complex Hilbert space. They specify assumptions that ensure the global existence of its solutions and allow them to derive its asymptotics at temporal infinity. They demonstrate that these assumptions are optimal in a suitable sense and more general than those used before. The evolution equation derives from the Brocketâe"Wegner flow that was proposed to diagonalize matrices and operators by a strongly continuous unitary flow. In fact, the solution of the non-linear flow equation leads to a diagonalization of Hamiltonian operators in boson quantum field theory which are quadratic in the field.

A strategy for implementing non-perturbative renormalisation of heavy-light four-quark operators in the static approximation

Energy Technology Data Exchange (ETDEWEB)

Palombi, F. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Gruppe Theorie; Papinutto, M. [Istituto Nazionale di Fisica Nucleare, Rome (Italy); Pena, C. [European Organization for Nuclear Research, Geneva (Switzerland). Theoretical Physics Div.; Wittig, H. [Mainz Univ. (Germany). Inst. fuer Kernphysik

2006-04-15

We discuss the renormalisation properties of the complete set of {delta}B=2 four-quark operators with the heavy quark treated in the static approximation. We elucidate the role of heavy quark symmetry and other symmetry transformations in constraining their mixing under renormalisation. By employing the Schroedinger functional, a set of non-perturbative renormalisation conditions can be defined in terms of suitable correlation functions. As a first step in a fully non-perturbative determination of the scale-dependent renormalisation factors, we evaluate these conditions in lattice perturbation theory at one loop. Thereby we verify the expected mixing patterns and determine the anomalous dimensions of the operators at NLO in the Schroedinger functional scheme. Finally, by employing twisted-mass QCD it is shown how finite subtractions arising from explicit chiral symmetry breaking can be avoided completely. (Orig.)

A strategy for implementing non-perturbative renormalisation of heavy-light four-quark operators in the static approximation

International Nuclear Information System (INIS)

Palombi, F.; Pena, C.; Wittig, H.

2006-04-01

We discuss the renormalisation properties of the complete set of ΔB=2 four-quark operators with the heavy quark treated in the static approximation. We elucidate the role of heavy quark symmetry and other symmetry transformations in constraining their mixing under renormalisation. By employing the Schroedinger functional, a set of non-perturbative renormalisation conditions can be defined in terms of suitable correlation functions. As a first step in a fully non-perturbative determination of the scale-dependent renormalisation factors, we evaluate these conditions in lattice perturbation theory at one loop. Thereby we verify the expected mixing patterns and determine the anomalous dimensions of the operators at NLO in the Schroedinger functional scheme. Finally, by employing twisted-mass QCD it is shown how finite subtractions arising from explicit chiral symmetry breaking can be avoided completely. (Orig.)

Transversals in non-discrete groups

Indian Academy of Sciences (India)

Transversals in non-discrete groups. RAMJI LAL and R P SHUKLA. Department of Mathematics, University of Allahabad, Allahabad 211 002, India. E-mail: ramjilal@mri.ernet.in; rps@mri.ernet.in. MS received 2 August 2004; revised 4 August 2005. Abstract. The concept of 'topological right transversal' is introduced to study ...

PD-L1 Expression and Survival among Patients with Advanced Non-Small Cell Lung Cancer Treated with Chemotherapy

DEFF Research Database (Denmark)

Sørensen, Steffen Filskov; Zhou, Wei; Dolled-Filhart, Marisa

2016-01-01

with advanced non-small cell lung cancer (NSCLC) treated with chemotherapy are inconsistent. MATERIAL AND METHODS: We evaluated the relationship between PD-L1 expression and overall survival (OS) among 204 patients with advanced NSCLC treated at Aarhus University Hospital, Aarhus, Denmark, from 2007 to 2012. PD......-positive tumors, and 50% had PD-L1 weak-positive tumors. No statistically significant association was found between PD-L1 expression and survival; adjusted hazard ratio of 1.34 (95% confidence interval, 0.88-2.03; median OS, 9.0 months) for the PD-L1 strong-positive group and 1.07 (0.74-1.55; median OS, 9...... by immunohistochemistry to be frequently expressed in patients with advanced NSCLC. However, PD-L1 expression is not a strong prognostic marker in patients with advanced NSCLC treated with chemotherapy....

Pseudo-differential operators groups, geometry and applications

CERN Document Server

Zhu, Hongmei

2017-01-01

This volume consists of papers inspired by the special session on pseudo-differential operators at the 10th ISAAC Congress held at the University of Macau, August 3-8, 2015 and the mini-symposium on pseudo-differential operators in industries and technologies at the 8th ICIAM held at the National Convention Center in Beijing, August 10-14, 2015. The twelve papers included present cutting-edge trends in pseudo-differential operators and applications from the perspectives of Lie groups (Chapters 1-2), geometry (Chapters 3-5) and applications (Chapters 6-12). Many contributions cover applications in probability, differential equations and time-frequency analysis. A focus on the synergies of pseudo-differential operators with applications, especially real-life applications, enhances understanding of the analysis and the usefulness of these operators.

A study of survival rate of the patients with esophageal carcinoma treated by pre- and/or post-operative irradiation

International Nuclear Information System (INIS)

Eida, Koichiro

1986-01-01

So far there is still considerable disagreement as to the evaluation of the pre- and postoperative irradiation effects on the survival rate of the patients with esophageal carcinoma. From April 1973 to December 1983, 138 cases of thoracic esophageal carcinoma were surgically operated upon at our Department; 68 cases were irradiated and 70 cases were not irradiated prior to the surgical operation. Followup study was done and its result has been reported in this communication. A few cases treated by pre-operative irradiation survived longer than the expected longevity in spite of their low curative operation rates. Prognosis was better in the cases with well differentiated squamous cell carcinoma, when marked or good responses to pre-operative irradiation with the calculated total dose of 30 Gy were recorded. There were differences in responsibility in the various histological types of esophageal carcinomas; good response in the group of well differentiated squamous carcinoma, less marked response in the groups of moderately and poorly differentiated squamous carcinomas, minor response in the types of undifferentiated and unclassifed carcinomas. From our observation it seems reasonable to say that prognosis of the patients with pre- and postoperative irradiation was better than that of those who received postoperative irradiation only. (author)

Long term outcome of ruptured vertebrobasilar artery dissection treated non-surgically

International Nuclear Information System (INIS)

Nakano, Takahiro; Ohkuma, Hiroki; Shimamura, Norihito; Munakata, Akira; Kikkawa, Tomoshige

2010-01-01

Vertebrobasilar artery dissection began to attract attention as a cause of subarachnoid hemorrhage (SAH) in the late 1970s. Although reports on this disease have gradually increased, the natural history of vertebrobasilar artery dissection remains obscure, and long-term follow-up of patients without surgical treatment is necessary to determine appropriate treatment. We describe the long-term clinical course of ruptured vertebrobasilar artery dissection treated non-surgically. Fourteen subjects with ruptured vertebrobasilar artery dissection were treated conservatively in 7 neurosurgical departments. We reviewed their clinical outcomes, image findings and the chronological changes at the dissection site from their charts. The modified Rankin Scale was Grade 0 in 13 of 14 cases, and Grade 2 in 1 case. The configuration of dissection did not change during the follow-up period in 12 of 14 cases, but occlusion and restoration were recognized in a single case each. Good prognosis was common in the patients with ruptured vertebrobasilar artery dissection who were treated non-surgically. It is essential to accumulate more data on the clinical course and changes in image findings of long-term survival cases to establish a definite strategy for ruptured vertebrobasilar artery dissection. (author)

Is non-operative management safe and effective for all splenic blunt trauma? A systematic review.

Science.gov (United States)

Cirocchi, Roberto; Boselli, Carlo; Corsi, Alessia; Farinella, Eriberto; Listorti, Chiara; Trastulli, Stefano; Renzi, Claudio; Desiderio, Jacopo; Santoro, Alberto; Cagini, Lucio; Parisi, Amilcare; Redler, Adriano; Noya, Giuseppe; Fingerhut, Abe

2013-09-03

The goal of non-operative management (NOM) for blunt splenic trauma (BST) is to preserve the spleen. The advantages of NOM for minor splenic trauma have been extensively reported, whereas its value for the more severe splenic injuries is still debated. The aim of this systematic review was to evaluate the available published evidence on NOM in patients with splenic trauma and to compare it with the operative management (OM) in terms of mortality, morbidity and duration of hospital stay. For this systematic review we followed the "Preferred Reporting Items for Systematic Reviews and Meta-analyses" statement. A systematic search was performed on PubMed for studies published from January 2000 to December 2011, without language restrictions, which compared NOM vs. OM for splenic trauma injuries and which at least 10 patients with BST. We identified 21 non randomized studies: 1 Clinical Controlled Trial and 20 retrospective cohort studies analyzing a total of 16,940 patients with BST. NOM represents the gold standard treatment for minor splenic trauma and is associated with decreased mortality in severe splenic trauma (4.78% vs. 13.5% in NOM and OM, respectively), according to the literature. Of note, in BST treated operatively, concurrent injuries accounted for the higher mortality. In addition, it was not possible to determine post-treatment morbidity in major splenic trauma. The definition of hemodynamic stability varied greatly in the literature depending on the surgeon and the trauma team, representing a further bias. Moreover, data on the remaining analyzed outcomes (hospital stay, number of blood transfusions, abdominal abscesses, overwhelming post-splenectomy infection) were not reported in all included studies or were not comparable, precluding the possibility to perform a meaningful cumulative analysis and comparison. NOM of BST, preserving the spleen, is the treatment of choice for the American Association for the Surgery of Trauma grades I and II

'Group value foresight' - Treating the nuclear interest in IVO Group Communications

International Nuclear Information System (INIS)

Heininen-Ojanpera, Marke

1999-01-01

Fortum is a new international energy group formed through the combination of the IVO Group and the Neste Group, two Finnish industrial groups with extensive operations in the energy sector in the Nordic countries and certain other countries throughout the world. IVO Group uses almost all fuels to generate electricity: nuclear, hydro, gas, oil, coal, peat, biomass, municipal waste, wind and solar. The main capacity is generated by nuclear, coal and water but gas, particularly in cogeneration, has been expected to grow. The major challenge in communicating is to find a balanced way of dealing with this variety so that the messages will be open and objective and, at the same time, not harming unnecessarily any of the generation forms in business terms. Moreover, new business procedures are welcome. The majority of the communicating issues deal with either competition or environmental questions under the threat of bad publicity and more strict regulatory controls. From the beginning, one of the working groups was responsible for defining the issues and sorting out the weak signals related to nuclear energy. In terms of corporate communications, special nuclear policies and messages have been worked out each year. For many reasons, the earlier nuclear policies and communication agendas have been unnecessarily strongly emphasising the nuclear option only. Today, the Group Value Foresight process, among others, has helped IVO to find the correct weighting of any nuclear issue and option in relation to other major forms of generation and related issues. The policies and messages have become more reasonable and more sensitive to changing situations in the market and in relation to public perception. There is less and less need for presenting the nuclear option in public with a quivering voice of offended authority

A FINANCIAL PERFORMANCE COMPARISON OF GROUP AND NON-GROUP FIRMS IN TEXTILE SECTOR OF PAKISTAN

Directory of Open Access Journals (Sweden)

Ishtiaq AHMAD

2016-12-01

Full Text Available Pakistan is a developing economy and business groups are key players of the Pakistan’s economy. Previous research evidence shows that in the emerging economies group affiliation creates value for the firms. This study is intended to empirically investigate to know that whether group affiliated (GA firms perform financially better than non-group affiliated firms or not? GA firms in emerging economies can have better financial performance by sharing tangible and intangible resources at group level. The financial ratio is used to compare performance of affiliated and non-group affiliated firms by using the data of 70 textile firms listed at Karachi Stock Exchange(now Pakistan Stock Exchange covering a period from 2008 to 2012. Based on mean values of return on assets (ROA, results of the study show that GA firms have higher financial performance than non-group affiliated firms in each year and over all five years.

Coherent Synchrotron Radiation A Simulation Code Based on the Non-Linear Extension of the Operator Splitting Method

CERN Document Server

Dattoli, Giuseppe

2005-01-01

The coherent synchrotron radiation (CSR) is one of the main problems limiting the performance of high intensity electron accelerators. A code devoted to the analysis of this type of problems should be fast and reliable: conditions that are usually hardly achieved at the same time. In the past, codes based on Lie algebraic techniques have been very efficient to treat transport problem in accelerators. The extension of these method to the non-linear case is ideally suited to treat CSR instability problems. We report on the development of a numerical code, based on the solution of the Vlasov equation, with the inclusion of non-linear contribution due to wake field effects. The proposed solution method exploits an algebraic technique, using exponential operators implemented numerically in C++. We show that the integration procedure is capable of reproducing the onset of an instability and effects associated with bunching mechanisms leading to the growth of the instability itself. In addition, parametric studies a...

Non-dense domain operator matrices and Cauchy problems

International Nuclear Information System (INIS)

Lalaoui Rhali, S.

2002-12-01

In this work, we study Cauchy problems with non-dense domain operator matrices. By assuming that the entries of an unbounded operator matrix are Hille-Yosida operators, we give a necessary and sufficient condition ensuring that the part of this operator matrix generates a semigroup in the closure of its domain. This allows us to prove the well-posedness of the corresponding Cauchy problem. Our results are applied to delay and neutral differential equations. (author)

The genetic diversity of commensal Escherichia coli strains isolated from nonantimicrobial treated pigs varies according to age group

DEFF Research Database (Denmark)

Ahmed, Shahana; Olsen, John E.; Herrero-Fresno, Ana

2017-01-01

This is the first report on the genetic diversity of commensal E. coli from pigs reared in an antibiotic free production system and belonging to different age groups. The study investigated the genetic diversity and relationship of 900 randomly collected commensal E. coli strains from non......-antimicrobial treated pigs assigned to five different age groups in a Danish farm. Fifty-two unique REP profiles were detected suggesting a high degree of diversity. The number of strains per pig ranged from two to 13. The highest and the lowest degree of diversity were found in the early weaners group (Shannon...... diversity index, H' of 2.22) and piglets (H' of 1.46) respectively. The REP profiles, R1, R7 and R28, were the most frequently observed in all age groups. E. coli strains representing each REP profile and additional strains associated with the dominant profiles were subjected to PFGE and were assigned to 67...

Blood pressure reduction in patients with irreversible pulpitis teeth treated by non-surgical root canal treatment

Directory of Open Access Journals (Sweden)

James I-Sheng Huang

2017-12-01

Full Text Available Background/purpose: The hypotension in patients during non-surgical root canal treatment (NSRCT has not yet investigated. This study aimed to assess the mean systolic blood pressure (MSBP, mean diastolic blood pressure (MDBP, and mean arterial blood pressure (MABP reduction percentages in patients with irreversible pulpitis teeth treated by NSRCT. Materials and methods: We prospectively recruited 111 patients with a total of 138 irreversible pulpitis teeth. All patients underwent two NSRCT sessions. The first NSRCT session involved mainly the removal of vital pulp tissue with the direct stimulation of the dental branches of the trigeminal nerve, and the second NSRCT session included the root canal debridement and enlargement with minimal disturbance to the dental nerves. The blood pressure of each patient was recorded before and during both NSRCT sessions. Results: There were significantly higher reduction percentages of MSBP, MDBP, and MABP in the first NSRCT session than in the second NSRCT session for all treated patients (all the P-values < 0.001. If the patients were divided into 2 or more groups according to the clinical variables including the patients' gender, age, tooth type, and anesthesia type, we also found significantly higher reduction percentages of MSBP, MDBP, and MABP in the first NSRCT session than in the second NSRCT session for all treated patients except for patients below 40 years of age and for patients with lower anterior teeth treated (all the P-values < 0.05. Conclusion: The decrease in blood pressure in patients receiving vital pulpal extirpation is a relatively common phenomenon. Keywords: hypotension, irreversible pulpitis teeth, non-surgical root canal treatment, blood pressure, parasympathetic effect, vital pulpal extirpation

3D GIS spatial operation based on extended Euler operators

Science.gov (United States)

Xu, Hongbo; Lu, Guonian; Sheng, Yehua; Zhou, Liangchen; Guo, Fei; Shang, Zuoyan; Wang, Jing

2008-10-01

The implementation of 3 dimensions spatial operations, based on certain data structure, has a lack of universality and is not able to treat with non-manifold cases, at present. ISO/DIS 19107 standard just presents the definition of Boolean operators and set operators for topological relationship query, and OGC GeoXACML gives formal definitions for several set functions without implementation detail. Aiming at these problems, based mathematical foundation on cell complex theory, supported by non-manifold data structure and using relevant research in the field of non-manifold geometry modeling for reference, firstly, this paper according to non-manifold Euler-Poincaré formula constructs 6 extended Euler operators and inverse operators to carry out creating, updating and deleting 3D spatial elements, as well as several pairs of supplementary Euler operators to convenient for implementing advanced functions. Secondly, we change topological element operation sequence of Boolean operation and set operation as well as set functions defined in GeoXACML into combination of extended Euler operators, which separates the upper functions and lower data structure. Lastly, we develop underground 3D GIS prototype system, in which practicability and credibility of extended Euler operators faced to 3D GIS presented by this paper are validated.

Application of the Non-Intervention Principle to Low-Intensity Cyber Operations

OpenAIRE

Adamson, Liisi

2015-01-01

Present work focuses on the non-intervention principle and low-intensity cyber operations. More specifically, its main question is, whether the principle of non-intervention applies to low-intensity cyber operations and if it does, is the legal framework of non-intervention principle an effective way to regulate peacetime low-intensity cyber operations. Information Age and the rapid development of ICTs have provided hostile actors the opportunity to exploit the advantages cyberspace offe...

Uptake and washout of I-123-MIBG in neuronal and non-neuronal sites in rat hearts. Relationship to renal clearance

International Nuclear Information System (INIS)

Arbab, A.S.; Koizumi, Kiyoshi; Araki, Tsutomu

1996-01-01

We investigated the uptake and washout of I-123-metaiodobenzylguanidine (MIBG) in neuronal (both intra-and extravesicular) and non-neuronal sites in the heart and its relationship to renal clearance. Acute renal failure was induced in rats by ligating the renal vessels, and the findings were compared with those of sham-operated rats. Each group consisted of control, reserpine-treated and 6-hydroxydopamine (6-OHDA)-treated subgroups. Rats were sacrificed at 10 minutes and 4 hours after injection of MIBG. MIBG activity was calculated in specimens of heart, spleen, lung and blood. At 10 minutes, no significant difference in MIBG uptake in the heart was observed among the subgroups or between sham-operated and renal failure rats despite a significantly higher blood MIBG activity in the latter. At 4 hours, however, the hearts of both reserpine-treated and 6-OHDA-treated rats showed significantly lower MIBG uptake than control rats. Furthermore, the hearts of renal failure rats showed higher MIBG uptake in the control and reserpine-treated rats than in the corresponding subgroups in sham-operated rats. Intra and extravesicular neuronal uptake of MIBG in the heart were estimated using control, reserpine-treated and 6-OHDA-treated rats. Vesicular uptake values were similar in both the sham-operated group (0.51% ID/g) and the renal failure group (0.44% ID/g). But extravesicular neuronal uptake values were quite different in the renal failure group (0.86% ID/g) and the sham-operated group (0.19% ID/g). In conclusion, uptake to and washout from extravesicular neuronal sites may depend on the concentration of MIBG in the blood or the state of renal clearance, but vesicular uptake may be independent of these factors. (author)

Gefitinib Plus Interleukin-2 in Advanced Non-Small Cell Lung Cancer Patients Previously Treated with Chemotherapy

Energy Technology Data Exchange (ETDEWEB)

Bersanelli, Melissa, E-mail: melissa.bersanelli@alice.it; Buti, Sebastiano; Camisa, Roberta [Oncology Unit, University Hospital of Parma, Via Gramsci, 14, 43126 Parma (Italy); Brighenti, Matteo; Lazzarelli, Silvia [Oncology Unit, Azienda Istituti Ospitalieri di Cremona, Largo Priori, 1, 26100 Cremona (Italy); Mazza, Giancarlo [Radiology Division, Spedali Civili di Brescia, P.le Spedali Civili,1, 25123 Brescia (Italy); Passalacqua, Rodolfo, E-mail: melissa.bersanelli@alice.it [1Oncology Unit, University Hospital of Parma, Via Gramsci, 14, 43126 Parma (Italy)

2014-09-30

The activation of lymphocytes by gefitinib treatment has been described. In this phase II pilot trial, we explored the possible synergism between IL-2 and gefitinib for non-small cell lung cancer (NSCLC) treatment. From September, 2003, to November, 2006, 70 consecutive patients with advanced, progressive NSCLC, previously treated with chemotherapy, received oral gefitinib 250 mg daily. The first 39 patients received gefitinib alone (G group). The other 31 also received subcutaneous IL-2 (GIL-2 group): 1 MIU/m{sup 2} (Million International Unit/m{sup 2})twice a day on Days 1 and 2, once a day on Days 3, 4, 5 every week for four consecutive weeks with a four-week rest period. Median follow-up was 25.2 months. Grade 3–4 toxicity of gefitinib was represented by skin rash (7%), asthenia/anorexia (6%) and diarrhea (7%); patients treated with IL-2 showed grade 2–3 fever (46%), fatigue (21%) and arthralgia (13%). In the GIL-2 group and G-group, we respectively observed: an overall response rate of 16.1% (6.4% complete response) and 5.1% (only partial response); a disease control rate of 41.9% and 41%; a median time to progression of 3.5 (CI 95% = 3.2–3.8) and 4.1 (CI 95% = 2.6–5.7) months; a median overall survival of 20.1 (CI 95% = 5.1–35.1) and 6.9 (CI 95% = 4.9–8.9) months (p = 0.002); and an actuarial one-year survival rate of 54% and 30%. Skin toxicity (p < 0.001; HR = 0.29; CI 95% = 0.16–0.54) and use of IL-2 (p < 0.001; HR = 0.33; CI 95% = 0.18–0.60) were independently associated with improvement of survival. In this consecutive, non-randomized, series of advanced NSCLC patients, the use of IL-2 increased the efficacy of gefitinib.

Gefitinib Plus Interleukin-2 in Advanced Non-Small Cell Lung Cancer Patients Previously Treated with Chemotherapy

Directory of Open Access Journals (Sweden)

Melissa Bersanelli

2014-09-01

Full Text Available The activation of lymphocytes by gefitinib treatment has been described. In this phase II pilot trial, we explored the possible synergism between IL-2 and gefitinib for non-small cell lung cancer (NSCLC treatment. From September, 2003, to November, 2006, 70 consecutive patients with advanced, progressive NSCLC, previously treated with chemotherapy, received oral gefitinib 250 mg daily. The first 39 patients received gefitinib alone (G group. The other 31 also received subcutaneous IL-2 (GIL-2 group: 1 MIU/m2 (Million International Unit/m2twice a day on Days 1 and 2, once a day on Days 3, 4, 5 every week for four consecutive weeks with a four-week rest period. Median follow-up was 25.2 months. Grade 3–4 toxicity of gefitinib was represented by skin rash (7%, asthenia/anorexia (6% and diarrhea (7%; patients treated with IL-2 showed grade 2–3 fever (46%, fatigue (21% and arthralgia (13%. In the GIL-2 group and G-group, we respectively observed: an overall response rate of 16.1% (6.4% complete response and 5.1% (only partial response; a disease control rate of 41.9% and 41%; a median time to progression of 3.5 (CI 95% = 3.2–3.8 and 4.1 (CI 95% = 2.6–5.7 months; a median overall survival of 20.1 (CI 95% = 5.1–35.1 and 6.9 (CI 95% = 4.9–8.9 months (p = 0.002; and an actuarial one-year survival rate of 54% and 30%. Skin toxicity (p < 0.001; HR = 0.29; CI 95% = 0.16–0.54 and use of IL-2 (p < 0.001; HR = 0.33; CI 95% = 0.18–0.60 were independently associated with improvement of survival. In this consecutive, non-randomized, series of advanced NSCLC patients, the use of IL-2 increased the efficacy of gefitinib.

Classification of non-solvable groups with a given property

Indian Academy of Sciences (India)

In this paper, we classify the finite non-solvable groups satisfying the following property P5: their orders of representatives are set-wise relatively prime for any 5 distinct non-central conjugacy classes. Keywords. Conjugacy classes; graph; Frobenius group; order. 2010 Mathematics Subject Classification. 20D60, 20E45. 1.

Euler polynomials and identities for non-commutative operators

Science.gov (United States)

De Angelis, Valerio; Vignat, Christophe

2015-12-01

Three kinds of identities involving non-commutating operators and Euler and Bernoulli polynomials are studied. The first identity, as given by Bender and Bettencourt [Phys. Rev. D 54(12), 7710-7723 (1996)], expresses the nested commutator of the Hamiltonian and momentum operators as the commutator of the momentum and the shifted Euler polynomial of the Hamiltonian. The second one, by Pain [J. Phys. A: Math. Theor. 46, 035304 (2013)], links the commutators and anti-commutators of the monomials of the position and momentum operators. The third appears in a work by Figuieira de Morisson and Fring [J. Phys. A: Math. Gen. 39, 9269 (2006)] in the context of non-Hermitian Hamiltonian systems. In each case, we provide several proofs and extensions of these identities that highlight the role of Euler and Bernoulli polynomials.

Advantages of forced non-steady operated trickle-bed reactors

NARCIS (Netherlands)

Boelhouwer, J.G.; Piepers, H.W.; Drinkenburg, A.A.H.

2002-01-01

Trickle-bed reactors are usually operated in the steady state trickle flow regime. Uneven liquid distribution and the formation of hot spots are the most serious problems experienced during trickle flow operation. In this paper, we advocate the use of non-steady state operation of trickle-bed

Treatment results of non-operated lung cancer by radiotherapy and radiochemotherapy

International Nuclear Information System (INIS)

Seino, Yasuo; Watarai, Jiro; Kobayashi, Mitsuru; Sashi, Ryuji; Shindo, Masaaki; Kato, Toshio

1993-01-01

The treatment results of 152 non-operated lung cancer patients were analyzed. Median survival times (MST; months) for all patients based on the stage (UICC'87) were 28 M (n=12) for stage I, 18 M (n=16) for stage II, 8 M (n=58) for stage III A, 6 M (n=46) for stage III B, and 4 M (n=20) for stage IV. The effect of combined radiochemotherapy was quite evident in small cell lung cancer (SCLC) patients. Here, the MST of the radiotherapy alone group (n=11) was 5 M, whereas that of radiochemotherapy group (n=14) was 12 M (p<0.05). In non-small cell lung cancer (NSCLC), the effect of radiochemotherapy was recognized only in stage III A and III B patients. In this case, the MST of the radiotherapy alone group (n=50) was 6 M, whereas that of the radiochemotherapy group (n=38) was 9 M (p<0.05). The duration of time from the initial therapy to the occurrence of distant metastasis in stage III A and III B patients was longer in the radiochemotherapy group than in the radiotherapy alone group (p<0.05). As for the metastatic sites, a delay in the occurrence of brain, lung and pleural metastasis was also recognized in the radiochemotherapy group (p<0.05). In this retrospective study, the value of combined radiochemotherapy was evident in SCLC and stage III-NSCLC patients. However, there was considerable case to case variation in the dosage, combination of agents and timing of chemotherapy. Recently, more aggressive chemotherapy is now being applied. (author)

Non-perturbative renormalisation of {delta}F=2 four-fermion operators in two-flavour QCD

Energy Technology Data Exchange (ETDEWEB)

Dimopoulos, P.; Vladikas, A. [INFN, Sezione di Roma II (Italy)]|[Rome-3 Univ. (Italy). Dipt. di Fisica; Herdoiza, G. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Palombi, F.; Papinutto, M. [CERN, Geneva (Switzerland). Physics Dept., TH Division; Pena, C. [Universidad Autonoma de Madrid (Spain). Dept. de Fisica Teorica C-XI]|[Univ. Autonoma de Madrid (Spain). Inst. de Fisica Teorica UAM/CSIC C-XVI; Wittig, H. [Mainz Univ. (Germany). Inst. fuer Kernphysik

2007-12-15

Using Schroedinger Functional methods, we compute the non-perturbative renormalisation and renormalisation group running of several four-fermion operators, in the framework of lattice simulations with two dynamical Wilson quarks. Two classes of operators have been targeted: (i) those with left-left current structure and four propagating quark fields; (ii) all operators containing two static quarks. In both cases, only the parity-odd contributions have been considered, being the ones that renormalise multiplicatively. Our results, once combined with future simulations of the corresponding lattice hadronic matrix elements, may be used for the computation of phenomenological quantities of interest, such as B{sub K} and B{sub B} (the latter also in the static limit). (orig.)

Operative treatment of the midshaft fractures of the clavicle – does delay matter?

Directory of Open Access Journals (Sweden)

Matej Andoljšek

2007-11-01

Full Text Available Background: Fractures of the clavicle are common injuries and mostly treated non-operatively. Nearly always the fracture is clinically united within three to four weeks and functional recovery should be completed within two months. Traditionally thinking has been that operative treatment is indicated exceptionaly and that delayed surgery is less successful. In retrospective comparative study authors have asked – whether delay of surgery in middle-third clavicular fractures negatively affects functional results and – whether after delayed surgery complications are more frequent.Patients and methods: Thirty-seven of 733 fractures of the clavicle were treated operatively. Among these, 11 were fresh Allman Type I fractures (early procedure, 9 delayed- or non-unions and one malunion (late procedure. All fractures were fixed with plates and screws. In none of the reconstructive procedures composite bone grafting was performed, twice spongiotic bone graft and twice morsilized calus grafts were used. DASH and Constant scores were used for outcome evaluation.Results: Twenty-one of 22 patients were evaluated (one foreign turist missed on average 21 month after surgery. Average DASH scores for early operated patients were 14.4 and for late operated 18.5; an average Quich DASH were 16.4 and 20.5 respectively. Average Constant scores were 85.6 and 76.0. Statistically differences are not important. Three patients had early complications (two from early, one from late group. Five patients had late complications (four skin paresthesias, one non-union.Conclusions: In retrospective study, functional results of surgically treated fresh Type I fractures and after reconstructive surgery for delayed-, non- and mal-union of the midshaft of the clavicle were comparable. No significant differences in complication rates were confirmed.

Working group on unbundling of electricity trade operations 2. A group report; Saehkoeliiketoimintojen eriyttaemistyoeryhmae 2. Tyoeryhmaen mietintoe

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-09-01

The current unbundling of operations in accounts has proved inadequate. No formula or model that could be made binding by provisions have been defined for unbundled accounts. In addition, unbundling can draw a distinct line between commercial activities and network operations, which have assumed various authoritative functions. Against this background, the need for clearer unbundling has become more marked. The working group suggests that the current provisions on unbundling of trade operations should be tightened and that the unbundling should be made clearer especially in terms of allocation of joint costs. For this, the necessary preparations by the authorities should be initiated urgently. At the same time, the working group proposes that network operations should be unbundled from other operations by incorporation or by unbundling them into a separate public utility. The smallest electric utilities should be exempted from the obligation of incorporating network operations. According to the working group, the lower limit could be fixed e.g. at 70 GWh a year. The working group also suggests that the licensees must own the electricity networks they operate. The licensees could not rent their networks from the mother company nor lease them from a financing company. The model proposed by the working group would redress the major problems connected with the supervision of the electricity market. The monopoly, i.e. the electricity network operations, under the supervision of the Electricity Market Authority could thus be unbundled. This would improve the functioning of the market and facilitate the supervision. However, the model would not abolish the tax concession of municipal public utilities in competitive trade operations, production and sale of electricity. The tax concession may affect the competitive situation on the electricity market. (orig.)

Peer groups and operational cycle enhancements to the performance indicator report

International Nuclear Information System (INIS)

Stromberg, H.M.; DeHaan, M.S.; Gentillon, C.D.; Wilson, G.E.; Vanden Heuvel, L.N.

1992-01-01

Accurate performance evaluation and plant trending by the performance indicator program are integral parts of monitoring the operation of commercial nuclear power plants. The presentations of the NRC/AEOD performance indicator program have undergone a number of enhancements. The diversity of the commercial nuclear plants, coupled with continued improvements in the performance indicator program, has resulted in the evaluation of plants in logical peer groups and highlighted the need to evaluate the impact of plant operational conditions on the performance indicators. These enhancements allow a more-meaningful evaluation of operating commercial nuclear power plant performance. This report proposes methods to enhance the presentation of the performance indicator data by analyzing the data in logical peer groups and displaying the performance indicator data based on the operational status of the plants. Previously, preliminary development of the operational cycle displays of the performance indicator data was documented. This report extends the earlier findings and presents the continued development of the peer groups and operational cycle trend and deviation data and displays. This report describes the peer groups and enhanced PI data presentations by considering the operational cycle phase breakdowns, calculation methods, and presentation methods

The forecasted hazard of primary hepatocellular carcinoma treated by interventional embolization

International Nuclear Information System (INIS)

Cui Shuzhong; Wang Yuandong; Liu Haiying; Ruan Zhongming; Tang Yunqiang; Hu Weimin; Wang Jiakang; Li Jianchang; Wang Bin; Cai Kuihua

2002-01-01

Objective: To evaluate the reserved liver function of the primary liver cancer treated by interventional embolization. Methods: 116 patients with primary liver cancer treated by interventional embolization were classified into three groups: the better, the lightly-damaged, and the highly-damaged according to the liver function after operation. The liver function and the reserved liver function among the three groups were analyzed with simple factor (Kruskal-Wallis) and multiple factors (Logistic). The damage of liver function was forecasted for primary liver cancer treated by interventional embolization. Results: There was no difference in the ALT, AST, CGT, ALP of the pre-operation among the three groups (P>0.05), but the difference in the ICGR15 and the grade of Child was obvious (P<0.05). The three equations forecasting group division after-operation with Logistic were counted and the total according rate was 82.76%. Conclusion: ICGR15 and the grade of Child were the better standard in evaluating the function of the primary liver cancer treated by interventional embolization. The strong evaluable evidence is provided for the interventional embolization of primary liver cancer

Is non-operative management still justified in the treatment of adhesive small bowel obstruction in children?

Science.gov (United States)

Nasir, Abdulrasheed A; Abdur-Rahman, Lukman O; Bamigbola, Kayode T; Oyinloye, Adewale O; Abdulraheem, Nurudeen T; Adeniran, James O

2013-01-01

Adhesive small bowel obstruction (ASBO) is a feared complication after abdominal operations in both children and adults. The optimal management of ASBO in the pediatric population is debated. The aim of the present study was to examine the safety and effectiveness of non-operative management in ASBO. A retrospective review of 33 patients who were admitted for ASBO over a 5-year period was carried out. Follow-up data were available for 29 patients. Demographic, clinical, and operative details and outcomes were collected for these patients. Data analysis was done with SPSS version 15.0. P ≤ 0.05 was regarded as significant. Out of 618 abdominal surgeries within the 5-year period, 34 admissions were recorded from 29 patients at the follow-up period of 1-28 months. There were 19 boys (65.5%). The median age of patients was 4.5 years. Typhoid intestinal perforation (n = 7), intussusception (n = 6), intestinal malrotation (n = 5), and appendicitis (n = 4) were the major indications for a prior abdominal surgery leading to ASBO. Twenty-five patients (73.5%) developed SBO due to adhesions within the first year of the primary procedure. Of the 34 patients admitted with ASBO, 18 (53%) underwent operative intervention and 16 (47%) were successfully managed non-operatively. There were no differences in sex (P = 0.24), initial procedure (P = 0.12), age, duration of symptoms, and time to re-admission between the patients who responded to non-operative management and those who underwent operative intervention. However, the length of hospital stay was significantly shorter in the non-operative group (P operative management is still a safe and preferred approach in selected patients with ASBO. However, 53% eventually required surgery.

Outcome of 289 locally advanced non-small cell lung cancer treated with radiotherapy alone and radiotherapy combined with chemotherapy

International Nuclear Information System (INIS)

Ou Guangfei; Wang Lvhua; Zhang Hongxing; Chen Dongfu; Xiao Zefen; Feng Qinfu; Zhou Zongmei; Lv Jima; Liang Jun; Wang Mei; Yin Weibo

2007-01-01

Objective: To retrospectively analyze the outcome of locally advanced non-small cell lung cancer patients treated with radiotherapy and chemoradiotherapy. Methods: 289 patients who were treated either by radiotherapy alone (168 patients) or radiotherapy plus chemotherapy (121 patients) from Dec. 1999 to Dec. 2002 were entered into the database for analysis. Pathological types: squamous cancer (152), adenocarcinoma(74), squamoadenocarcinoma(2) and other types (2). 24 showed cancer unclassificable and 35 were diagnosed without pathological proof. Stages: 74 had III A and 215 III B stage disease. Among the 121 patients treated with combined modality, 24 were treated with concurrent chemoradiotherapy, 78 radiotherapy after chemotherapy(C + R), and 19 radiotherapy followed by chemotherapy(R + C). In patients treated by concurrent chemoradiotherapy or C + R, 38 received consolidation chemotherapy after induction treatment. Results: The 1-, 3-, 5-year overall survival, and the median survival were: 45% , 16% , 8%, and 16.2 months for all patients; 57%, 27%, 11%, and 21.7 months for stage IIIA; 41%, 12%, 7%, and 15.3 months for IIIB. By logrank test, clinical stage, KPS performance, tumor volume, hemoglobin level before treatment, consolidation chemotherapy, radiation dose, and response to treatment showed statistically dramatic impact on overall survival. The overall survival rate and median survival time were slightly higher in the combined group than in the radiotherapy alone group, but the difference is statistically insignificant. In Cox multivariable regression, stage and consolidation chemotherapy were independent prognostic factors; KPS performance, radiation dose, and response to treatment were at the margin of statistical significance. Esophagitis and pneumonitis of Grade II or higher were 24% and 8%, respectively. Failure sites included in the thorax(41%), outside of thorax(48%), and both in and outside the thorax(11%). There was no difference between the

Non-Power Reactor Operator Licensing Examiner Standards

International Nuclear Information System (INIS)

1994-06-01

The Non-Power Reactor Operator Licensing Examiner Standards provide policy and guidance to NRC examiners and establish the procedures and practices for examining and licensing of applicants for NRC operator licenses pursuant to Part 55 of Title 10 of the Code of Federal Regulations (10 CFR Part 55). They are intended to assist NRC examiners and facility licensees to understand the examination process better and to provide for equitable and consistent administration of examinations to all applicants by NRC examiners. These standards are not a substitute for the operator licensing regulations and are subject to revision or other internal operator examination licensing policy changes. As appropriate, this standard will be revised periodically to accommodate comments and reflect new information or experience

Non-Abelian Stokes theorem for the Wilson loop operator in an arbitrary representation and its implication to quark confinement

Science.gov (United States)

Matsudo, Ryutaro; Kondo, Kei-Ichi

2015-12-01

We give a gauge-independent definition of magnetic monopoles in the S U (N ) Yang-Mills theory through the Wilson loop operator. For this purpose, we give an explicit proof of the Diakonov-Petrov version of the non-Abelian Stokes theorem for the Wilson loop operator in an arbitrary representation of the S U (N ) gauge group to derive a new form for the non-Abelian Stokes theorem. The new form is used to extract the magnetic-monopole contribution to the Wilson loop operator in a gauge-invariant way, which enables us to discuss confinement of quarks in any representation from the viewpoint of the dual superconductor vacuum.

Rubinstein-Taybi syndrome predisposing to non-WNT, non-SHH, group 3 medulloblastoma.

Science.gov (United States)

Bourdeaut, Franck; Miquel, Catherine; Richer, Wilfrid; Grill, Jacques; Zerah, Michel; Grison, Camille; Pierron, Gaelle; Amiel, Jeanne; Krucker, Clementine; Radvanyi, Francois; Brugieres, Laurence; Delattre, Olivier

2014-02-01

Medulloblastomas (MB) are classified in four subgroups: the well defined WNT and Sonic Hedgehog (SHH) subgroups, and the less defined groups 3 and 4. They occasionally occur in the context of a cancer predisposition syndrome. While germline APC mutations predispose to WNT MB, germline mutations in SUFU, PTCH1, and TP53 predispose to SHH tumors. We report on a child with a Rubinstein-Taybi syndrome (RTS) due to a germline deletion in CREBBP, who developed a MB. Biological profilings demonstrate that this tumor belongs to the group 3. RTS may therefore be the first predisposition syndrome identified for non-WNT/non-SHH MB. © 2013 Wiley Periodicals, Inc.

Euler Polynomials and Identities for Non-Commutative Operators

OpenAIRE

De Angelis, V.; Vignat, C.

2015-01-01

Three kinds of identities involving non-commutating operators and Euler and Bernoulli polynomials are studied. The first identity, as given by Bender and Bettencourt, expresses the nested commutator of the Hamiltonian and momentum operators as the commutator of the momentum and the shifted Euler polynomial of the Hamiltonian. The second one, due to J.-C. Pain, links the commutators and anti-commutators of the monomials of the position and momentum operators. The third appears in a work by Fig...

Language dominance shapes non-linguistic rhythmic grouping in bilinguals.

Science.gov (United States)

Molnar, Monika; Carreiras, Manuel; Gervain, Judit

2016-07-01

To what degree non-linguistic auditory rhythm perception is governed by universal biases (e.g., Iambic-Trochaic Law; Hayes, 1995) or shaped by native language experience is debated. It has been proposed that rhythmic regularities in spoken language, such as phrasal prosody affect the grouping abilities of monolinguals (e.g., Iversen, Patel, & Ohgushi, 2008). Here, we assessed the non-linguistic tone grouping biases of Spanish monolinguals, and three groups of Basque-Spanish bilinguals with different levels of Basque experience. It is usually assumed in the literature that Basque and Spanish have different phrasal prosodies and even linguistic rhythms. To confirm this, first, we quantified Basque and Spanish phrasal prosody (Experiment 1a) and duration patterns used in the classification of languages into rhythm classes (Experiment 1b). The acoustic measurements revealed that regularities in phrasal prosody systematically differ across Basque and Spanish; by contrast, the rhythms of the two languages are only minimally dissimilar. In Experiment 2, participants' non-linguistic rhythm preferences were assessed in response to non-linguistic tones alternating in either intensity (Intensity condition) or in duration (Duration condition). In the Intensity condition, all groups showed a trochaic grouping bias, as predicted by the Iambic-Trochaic Law. In the Duration Condition the Spanish monolingual and the most Basque-dominant bilingual group exhibited opposite grouping preferences in line with the phrasal prosodies of their native/dominant languages, trochaic in Basque, iambic in Spanish. The two other bilingual groups showed no significant biases, however. Overall, results indicate that duration-based grouping mechanisms are biased toward the phrasal prosody of the native and dominant language; also, the presence of an L2 in the environment interacts with the auditory biases. Copyright © 2016 Elsevier B.V. All rights reserved.

Low-term results from non-conventional partial arthroplasty for treating rotator cuff arthroplasthy

Directory of Open Access Journals (Sweden)

Antônio Carlos Tenor Júnior

2015-06-01

Full Text Available OBJECTIVE: To evaluate the evolution of the functional results from CTA(rhemiarthroplasty for surgically treating degenerative arthroplathy of the rotator cuff, with a mean follow-up of 5.4 years.METHODS: Eighteen patients who underwent CTA(r partial arthroplasty to treat degenerative arthroplathy of the rotator cuff between April 2007 and June 2009 were reevaluated, with minimum and mean follow-ups of 4.6 years and 5.4 years, respectively. Pre and postoperative parameters for functionality and patient satisfaction were used (functional scale of the University of California in Los Angeles, UCLA. All the patients underwent prior conservative treatment for 6 months and underwent surgical treatment because of the absence of satisfactory results. Patients were excluded if they presented any of the following: previous shoulder surgery; pseudoparalysis; insufficiency of the coracoacromial arch (type 2 B in Seebauer's classification; neurological lesions; or insufficiency of the deltoid muscle and the subscapularis muscle.RESULTS: With a mean follow-up of 5.4 years, 14 patients considered that they were satisfied with the surgery (78%; the mean range of joint motion for active elevation improved from 55.8° before the operation to 82.0° after the operation; the mean external rotation improved from 18.9° before the operation to 27.3° after the operation; and the mean medial rotation remained at the level of the third lumbar vertebra. The mean UCLA score after the mean follow-up of 5.4 years was 23.94 and this was an improvement in comparison with the preoperative mean and the mean 1 year after the operation.CONCLUSION: The functional results from CTA(r hemiarthroplasty for treating rotator cuff arthroplasty in selected patients remained satisfactory after a mean follow-up of 5.4 years.

2006 Annual Operations Report for INTEC Operable Unit 3-13, Group 1, Tank Farm Interim Action

International Nuclear Information System (INIS)

D. E. Shanklin

2007-01-01

This annual operations report describes the requirements followed and activities conducted to inspect, monitor, and maintain the items installed during performance of the Waste Area Group 3, Operable Unit 3-13, Group 1, Tank Farm Interim Action, at the Idaho Nuclear Technology and Engineering Center. This report covers the time period from January 1 through December 31, 2006, and describes inspection and monitoring activities for the surface-sealed areas within the tank farm, concrete-lined ditches and culverts in and around the tank farm, the lift station, and the lined evaporation pond. These activities are intended to assure that the interim action is functioning adequately to meet the objectives stated in the Operable Unit 3-13, Record of Decision for the Group 1, Tank Farm Interim Action (DOE/ID-10660) as described in the Group 1 Remedial Design/Remedial Action Work Plan (DOE/ID-10772)

Non-Supramenable Groups Acting on Locally Compact Spaces

DEFF Research Database (Denmark)

Kellerhals, Julian; Monod, Nicolas; Rørdam, Mikael

2013-01-01

Supramenability of groups is characterised in terms of invariant measures on locally compact spaces. This opens the door to constructing interesting crossed product $C^*$-algebras for non-supramenable groups. In particular, stable Kirchberg algebras in the UCT class are constructed using crossed ...

On an inequality for non-normal operators

International Nuclear Information System (INIS)

Duggal, B.P.

1992-07-01

Starting from the inequality proved by Takayuki Furuta for a dominant operator A on a complex Hilbert space H, which extends to all operators such that the pure part of A has empty point spectrum, it is shown that if A is a contraction (on a separable complex Hilbert space) with simple eigenvalues and C 0 completely non-unitary part, and if (1-A*A) 1/2 is of Hilbert-Schmidt class, then the said inequality holds for A. 8 refs

Products of composite operators in the exact renormalization group formalism

Science.gov (United States)

Pagani, C.; Sonoda, H.

2018-02-01

We discuss a general method of constructing the products of composite operators using the exact renormalization group formalism. Considering mainly the Wilson action at a generic fixed point of the renormalization group, we give an argument for the validity of short-distance expansions of operator products. We show how to compute the expansion coefficients by solving differential equations, and test our method with some simple examples.

Respiratory training during rehabilitation of acute organic fluorine-poisoned patients treated by non-invasive positive pressure ventilation.

Science.gov (United States)

Liu, L; Liu, D Z; Wang, Q P; Zhu, Z L; Li, H M; Lu, X Y

2017-01-01

This paper aimed to analyze the effects of respiratory training on pulmonary function during the rehabilitation period for acute organic fluorine-poisoned patients treated by non-invasive positive pressure ventilation (NIPPV). Sixty-two acute organic fluorine-poisoned patients admitted to the Xinxiang Central Hospital, Xinxiang City, China, from May 2012 to March 2016 were selected and randomly divided into an observation group and a control group, with 31 cases in each. Both groups received NIPPV. The patients in the control group exercised daily, while the patients in the observation group received contracting lips-abdominal breathing training. The therapeutic effects, pulmonary ventilation function, serum levels of α-antitrypsin1 (α-AT1), surfactant protein D (SP-D), neutrophil elastase (NE), transforming growth factor beta 1 (TGF-β1), and quality of life were analyzed and compared between the two groups both before and after the administration of treatment. The total effective rate of the observation group was 93.55%, which was significantly higher when compared with the control group (74.19%) (P less than 0.05). The levels of forced expiratory volume in one second (FEV1), FEV1/FVC ratio, vital capacity (VC), carbon monoxide diffusion capacity (DLco), and maximal voluntary ventilation (MVV) of the observation group were better when compared with the control group and had statistical significance (P less than 0.05). Before treatment, the serum levels of α-AT1, SP-D, NE, and TGF-β1, and quality of life had no statistical significance in either group (P>0.05); after treatment, these indexes and the quality of life for the observation group were significantly higher when compared with the control group, with statistical significance (P less than 0.05). The respiratory training in acute organic fluorine-poisoned patients treated by NIPPV can improve the serum indexes, dilute toxicity, and recover pulmonary function, which play key roles in improving the

Long-term functional outcome after type A3 spinal fractures : operative versus non-operative treatment

NARCIS (Netherlands)

Post, Richard B.; van der Sluis, Corry K.; Leferink, Vincent J. M.; ten Duis, Henk-Jan

The authors retrospectively studied, by questionnaires, the long-term (5 years) functional outcome after operative (posterior instrumentation : 38 cases) and non-operative treatment (25 cases) for type A3 spinal fractures (Comprehensive Classification) without neurological deficit. A possible bias

African Network Operators Group (AfNOG) Training Workshops and ...

International Development Research Centre (IDRC) Digital Library (Canada)

The African Network Operators Group (AfNOG) is a forum for technical cooperation and coordination between African network operators and engineers from the region's universities, research institutions and industry. This year, AfNOG's training workshops and meetings will be held in Rabat, Morocco, between 24 May and 6 ...

Temozolomide in patients with advanced non-small cell lung cancer with and without brain metastases. a phase II study of the EORTC Lung Cancer Group (08965).

NARCIS (Netherlands)

Dziadziuszko, R; Ardizzoni, A.; Postmus, P.E.; Smit, E.F.; Price, A; Debruyne, C.; Legrand, C; Giaccone, G.

2003-01-01

This study was performed to evaluate the activity of single-agent temozolomide in two groups of chemotherapy-naive non-small cell lung cancer (NSCLC) patients, with (12 patients) and without (13 patients) brain metastases (BM). Patients in both groups were treated with temozolomide 200 mg/m(2)/day,

Operating room nursing directors' influence on anesthesia group operating room productivity.

Science.gov (United States)

Masursky, Danielle; Dexter, Franklin; Nussmeier, Nancy A

2008-12-01

Implementation of initiatives to increase anesthesia group productivity depends not just on anesthesia groups, but on operating room (OR) nursing administration. OR nursing directors may encourage organizational change based on the needs of their hospitals and nurses. These changes may differ from those that would increase the anesthesia group's productivity. We assessed reward structures using (A) letters of nomination for the "OR Manager of the Year" award offered annually by the publication OR Manager, and (B) data from a salary/career survey of OR directors by the same publication. (A) There were 164 nomination letters submitted from 2004 through 2007 for 45 nominees. The letters contained n = 2659 full sentences and n = 50,821 words. We systematically created a list of 36 terms related to finance, profit, and productivity. We also analyzed the frequency of use of these terms relative to the use of the 15 most common relationship-oriented terms (e.g., compassion, encourage, mentor, and respect). (B) The salary/career survey's questions relevant to anesthesia group productivity had responses from 303 US OR directors, 97% of whom were nurses. We tested the strength of the relationship between the budget responsibility of the OR nursing director and his or her annual salary. (A) 2.6% of sentences in the nomination letters included at least one term related to profit and productivity (95% confidence interval 2.0%-3.2%). Relationship-oriented terms were 9.0 times more prevalent (95% confidence interval 7.1-11.4). (B) There was statistically significant positive proportionality between the OR nursing director's operational budget (including personnel) and his or her salary (Pearson r = 0.64, P time and OR nursing labor costs. Resulting decisions can differ from those that would increase the productivity (profit) of the anesthesia group. Anesthesia groups need to champion initiatives to increase anesthesia productivity, while being sensitive to institutional

Non-operative management of blunt hepatic trauma: Does angioembolization have a major impact?

Science.gov (United States)

Bertens, K A; Vogt, K N; Hernandez-Alejandro, R; Gray, D K

2015-02-01

A paradigm shift toward non-operative management (NOM) of blunt hepatic trauma has occurred. With advances in percutaneous interventions, even severe liver injuries are being managed non-operatively. However, although overall mortality is decreased with NOM, liver-related morbidity remains high. This study was undertaken to explore the morbidity and mortality of blunt hepatic trauma in the era of angioembolization (AE). A retrospective cohort of trauma patients with blunt hepatic injury who were assessed at our centre between 1999 and 2011 were identified. Logistic regression was undertaken to identify factors increasing the likelihood of operative management (OM) and mortality. We identified 396 patients with a mean ISS of 33 (± 14). Sixty-two (18%) patients had severe liver injuries (≥ AAST grade IV). OM occurred in 109 (27%) patients. Logistic regression revealed high ISS (OR 1.07; 95% CI 1.05-1.10), and lower systolic blood pressure on arrival (OR 0.98; 95% CI 0.97-0.99) to be associated with OM. The overall mortality was 17%. Older patients (OR 1.05; 95% CI 1.03-1.07), those with high ISS (OR 1.11; 95% CI 1.08-1.14) and those requiring OM (OR 2.89; 95% CI 1.47-5.69) were more likely to die. Liver-related morbidities occurred in equal frequency in the OM (23%) and AE (29%) groups (p = 0.32). Only 3% of those with NOM experienced morbidity. The majority of patients with blunt hepatic trauma can be successfully managed non-operatively. Morbidity associated with NOM was low. Patients requiring AE had morbidity similar to OM.

Effectiveness of surgery and individualized high-dose hyperfractionated accelerated radiotherapy on survival in clinical stage I non-small cell lung cancer. A propensity score matched analysis

International Nuclear Information System (INIS)

Jimenez, Marcelo F.; Baardwijk, Angela van; Aerts, Hugo J.W.L.; De Ruysscher, Dirk; Novoa, Nuria M.; Varela, Gonzalo; Lambin, Philippe

2010-01-01

Background and purpose: Surgery is considered the treatment of choice for early-stage non-small cell lung cancer (NSCLC). Patients with poor pulmonary function or other comorbidities are treated with radiotherapy. The objective of this investigation is to compare the 3-year survival of two early-stage NSCLC populations treated in two different hospitals, either by surgical resection (lobectomy) or by individualized high-dose accelerated radiotherapy, after matching patients by propensity scoring analysis. Methods: A retrospective comparative study has been performed on two series of consecutive patients with cytohistological diagnosis of NSCLC, clinically staged IA by means of PET-scan (radiotherapy group) and pathologically staged IA (surgery group). Results: A total of 157 cases were initially selected for the analysis (110 operated and 47 treated by radiotherapy). Patients in the radiotherapy group were older, with higher comorbidity and lower FEV1% with 3-years probability of survival for operated patients higher than that found for patients treated by radiotherapy. After matching by propensity scoring (using age and FEV1%), differences disappear and 3-years probability of survival had no statistical differences. Conclusions: Although this is a non-randomized retrospective analysis, we have not found 3-years survival differences after matching cases between surgery and radiotherapy. Nevertheless, data presented here support the continuous investigation for non-surgical alternatives in this disease.

Non-perturbative renormalization of three-quark operators

Energy Technology Data Exchange (ETDEWEB)

Goeckeler, Meinulf [Regensburg Univ. (Germany). Inst. fuer Theoretische Physik; Horsley, Roger [Edinburgh Univ. (United Kingdom). School of Physics and Astronomy; Kaltenbrunner, Thomas [Regensburg Univ. (DE). Inst. fuer Theoretische Physik] (and others)

2008-10-15

High luminosity accelerators have greatly increased the interest in semi-exclusive and exclusive reactions involving nucleons. The relevant theoretical information is contained in the nucleon wavefunction and can be parametrized by moments of the nucleon distribution amplitudes, which in turn are linked to matrix elements of local three-quark operators. These can be calculated from first principles in lattice QCD. Defining an RI-MOM renormalization scheme, we renormalize three-quark operators corresponding to low moments non-perturbatively and take special care of the operator mixing. After performing a scheme matching and a conversion of the renormalization scale we quote our final results in the MS scheme at {mu}=2 GeV. (orig.)

2005 Annual Operations Report for INTEC Operable Unit 3-13, Group 1, Tank Farm Interim Action

International Nuclear Information System (INIS)

D. Shanklin

2006-01-01

This annual operations report describes the requirements followed and activities conducted to inspect, monitor, and maintain the items installed during performance of the Waste Area Group 3, Operable Unit 3-13, Group 1, Tank Farm Interim Action, at the Idaho Nuclear Technology and Engineering Center. This report describes inspection and monitoring activities for the surface-sealed areas within the tank farm, concrete-lined ditches and culverts in and around the tank farm, the lift station, and the lined evaporation pond. These activities are intended to assure that the interim action is functioning adequately to meet the objectives stated in the Operable Unit 3-13, Record of Decision for the Group 1, Tank Farm Interim Action, (DOE/ID-10660) and as amended by the agreement to resolve dispute, which was effective in February 2003

Non-operative management of right side thoracoabdominal penetrating injuries--the value of testing chest tube effluent for bile.

Science.gov (United States)

De Rezende Neto, João Baptista; Guimarães, Tiago Nunes; Madureira, João Lopo; Drumond, Domingos André Fernandes; Leal, Juliana Campos; Rocha, Aroldo; Oliveira, Rodrigo Guimarães; Rizoli, Sandro B

2009-05-01

While mandatory surgery for all thoracoabdominal penetrating injuries is advocated by some, the high rate of unnecessary operations challenges this approach. However, the consequences of intrathoracic bile remains poorly investigated. We sought to evaluate the outcome of patients who underwent non-operative management of right side thoracoabdominal (RST) penetrating trauma, and the levels of bilirubin obtained from those patients' chest tube effluent. We managed non-operatively all stable patients with a single RST penetrating injury. Chest tube effluent samples were obtained six times within (4-8 h; 12-16 h; 20-24 h; 28-32 h; 36-40 h; 48 h and 72 h) of admission for bilirubin measurement and blood for complete blood count, bilirubin, alanine (ALT) and aspartate aminotransferases (AST) assays. For comparison we studied patients with single left thoracic penetrating injury. Forty-two patients with RST injuries were included. All had liver and lung injuries confirmed by CT scans. Only one patient failed non-operative management. Chest tube bilirubin peaked at 48 h post-trauma (mean 3.3+/-4.1 mg/dL) and was always higher than both serum bilirubin (pchest tube effluent from control group (27 patients with left side thoracic trauma). Serum ALT and AST were higher in RST injury patients (ptrauma appears to be safe. Bile originating from the liver injury reaches the right thoracic cavity but does not reflect the severity of that injury. The highest concentration was found in the patient failing non-operative management. The presence of intrathoracic bile in selected patients who sustain RST penetrating trauma, with liver injury, does not preclude non-operative management. Our study suggests that monitoring chest tube effluent bilirubin may provide helpful information when managing a patient non-operatively.

Observation of behavioural markers of non-technical skills in the operating room and their relationship to intra-operative incidents.

Science.gov (United States)

Siu, Joey; Maran, Nikki; Paterson-Brown, Simon

2016-06-01

The importance of non-technical skills in improving surgical safety and performance is now well recognised. Better understanding is needed of the impact that non-technical skills of the multi-disciplinary theatre team have on intra-operative incidents in the operating room (OR) using structured theatre-based assessment. The interaction of non-technical skills that influence surgical safety of the OR team will be explored and made more transparent. Between May-August 2013, a range of procedures in general and vascular surgery in the Royal Infirmary of Edinburgh were performed. Non-technical skills behavioural markers and associated intra-operative incidents were recorded using established behavioural marking systems (NOTSS, ANTS and SPLINTS). Adherence to the surgical safety checklist was also observed. A total of 51 procedures were observed, with 90 recorded incidents - 57 of which were considered avoidable. Poor situational awareness was a common area for surgeons and anaesthetists leading to most intra-operative incidents. Poor communication and teamwork across the whole OR team had a generally large impact on intra-operative incidents. Leadership was shown to be an essential set of skills for the surgeons as demonstrated by the high correlation of poor leadership with intra-operative incidents. Team-working and management skills appeared to be especially important for anaesthetists in the recovery from an intra-operative incident. A significant number of avoidable incidents occur during operative procedures. These can all be linked to failures in non-technical skills. Better training of both individual and team in non-technical skills is needed in order to improve patient safety in the operating room. Copyright © 2014 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.

7 CFR 3415.10 - Establishment and operation of peer review groups.

Science.gov (United States)

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Establishment and operation of peer review groups... ASSESSMENT RESEARCH GRANTS PROGRAM Scientific Peer Review of Research Grant Applications § 3415.10 Establishment and operation of peer review groups. Subject to § 3415.5, the Administrator shall adopt procedures...

7 CFR 3400.10 - Establishment and operation of peer review groups.

Science.gov (United States)

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Establishment and operation of peer review groups... GRANTS PROGRAM Scientific Peer Review of Research Grant Applications § 3400.10 Establishment and operation of peer review groups. Subject to § 3400.5, the Administrator will adopt procedures for the...

7 CFR 3401.12 - Establishment and operation of peer review groups.

Science.gov (United States)

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Establishment and operation of peer review groups... GRANTS PROGRAM Scientific Peer Review of Research Applications for Funding § 3401.12 Establishment and operation of peer review groups. Subject to § 3401.7, the Administrator will adopt procedures for the...

7 CFR 3411.10 - Establishment and operation of peer review groups.

Science.gov (United States)

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Establishment and operation of peer review groups... INITIATIVE COMPETITIVE GRANTS PROGRAM Scientific Peer Review of Research Grant Applications § 3411.10 Establishment and operation of peer review groups. Subject to § 3411.5, the Administrator shall adopt procedures...

Death Anxiety in Clinical and Non-Clinical Groups

Science.gov (United States)

Abdel-Khalek, Ahmed M.

2005-01-01

The Arabic Scale of Death Anxiety (ASDA) was administered, individually, to 7 groups (N=765) of Egyptian normal participants (non-clinical), anxiety disorder patients, and patients suffering from schizophrenia (males and females), and addicts (males only). They were generally matched as groups according to age, occupation, and education. The…

Effects of deltamethrin treated uniform on malaria prophylaxis in troops of Bahawalpur garrison

International Nuclear Information System (INIS)

Younis, M.; Murtaza, G.; Nasir

2017-01-01

Objective: To determine the efficacy of deltamethrin treated uniforms on repellant action against mosquitos in serving soldiers. Study Design: Randomized control trial. Place and Duration of Study: Bahawalpur Garrison, from 18 Aug to 24 Aug 2014. Patient and Methods: Two groups were selected for the study, one group comprising of 100 x soldiers wearing deltamethrin treated uniforms and other group comprising 100 x soldiers wearing non-treated (normal working) uniforms-control group. All soldiers were males, their age ranged from 20 years to 41 year. Uniforms were issued centrally with no group knowing which group has been issued treated uniforms, (double blind study was carried out to eliminate subject bias). Coding system was evolved while issuing the uniforms which were only known to the main researchers, president of the study board. Both the groups were made to sit for one hour in a large training ground of the formation in two separate groups at a distance of 50-60 feet between the groups and 10-15 feet between the individuals. All the individuals were asked to count the number of mosquitos attracted towards them, whether sitting/biting on their uniforms or on their bodies. Mosquito counting was also facilitated by the organizing/conducting staff. The study continued for a week from 18-24 Aug 2014. All soldiers were given 2 x tabs Chloroquine stat as prophylaxis for malaria prior to the study. Mean and SD of no of bites of both groups were compared and analyzed. Student t-test was applied to note the statistical significance among the study groups. Results: Out of the two groups the individuals wearing deltamethrin treated uniforms showed about overall 90 percent protection from mosquitos as compared to the control group. The average number of bites by mosquitoes in the control group was 7/person in one hour, whereas it was less than one bite/person in the case group. Conclusion: This study confirmed that the deltamethrin treated uniform is highly effective in

Quantum channels irreducibly covariant with respect to the finite group generated by the Weyl operators

Science.gov (United States)

Siudzińska, Katarzyna; Chruściński, Dariusz

2018-03-01

In matrix algebras, we introduce a class of linear maps that are irreducibly covariant with respect to the finite group generated by the Weyl operators. In particular, we analyze the irreducibly covariant quantum channels, that is, the completely positive and trace-preserving linear maps. Interestingly, imposing additional symmetries leads to the so-called generalized Pauli channels, which were recently considered in the context of the non-Markovian quantum evolution. Finally, we provide examples of irreducibly covariant positive but not necessarily completely positive maps.

Non-group A streptococci in the pharynx. Pathogens or innocent bystanders?

Science.gov (United States)

Hayden, G F; Murphy, T F; Hendley, J O

1989-07-01

To determine whether beta-hemolytic streptococci from groups other than A are an important cause of sporadic pharyngitis in children. Cross-sectional, case-referent survey. General pediatric clinic at a military base in Ohio. One hundred fifty children with symptomatic pharyngitis and 150 controls matched for age and time of presentation over a 20-month study period. None. Anaerobic culture technique was used to improve isolation of beta-hemolytic streptococci. Group A beta-hemolytic streptococci were detected significantly more often among the ill children than among the controls (39% vs 16%, respectively). In contrast, non-group A beta-hemolytic streptococci were isolated in similar frequency from the ill and control children (17% vs 21%, respectively). Non-group A beta-hemolytic streptococci from groups B, C, F, and G were each isolated in similar frequency among the ill and control children. The isolation rate of non-group A organisms increased with age among both patients and controls. Non-group A beta-hemolytic streptococci seemed not to be an important cause of sporadic pharyngitis in this pediatric population.

Prolonged operative time increases infection rate in tibial plateau fractures.

Science.gov (United States)

Colman, Matthew; Wright, Adam; Gruen, Gary; Siska, Peter; Pape, Hans-Christoph; Tarkin, Ivan

2013-02-01

Fractures of the tibial plateau present a treatment challenge and are susceptible to both prolonged operative times and high postoperative infection rates. For those fractures treated with open plating, we sought to identify the relationship between surgical site infection and prolonged operative time as well as to identify other surgical risk factors. We performed a retrospective controlled analysis of 309 consecutive unicondylar and bicondylar tibial plateau fractures treated with open plate osteosynthesis at our institution's level I trauma centre during a recent 5-year period. We recorded operative times, injury characteristics, surgical treatment, and need for operative debridement due to infection. Operative times of infected cases were compared to uncomplicated surgical cases. Multivariable logistic regression analysis was performed to identify independent risk factors for postoperative infection. Mean operative time in the infection group was 2.8h vs. 2.2h in the non-infected group (p=0.005). 15 fractures (4.9%) underwent four compartment fasciotomies as part of their treatment, with a significantly higher infection rate than those not undergoing fasciotomy (26.7% vs. 6.8%, p=0.01). Open fracture grade was also significantly related to infection rate (closed fractures: 5.3%, grade 1: 14.3%, grade 2: 40%, grade 3: 50%, pinfection rates (13.9% vs. 8.7%, p=0.36). Multivariable logistic regression analysis of the entire study group identified longer operative times (OR 1.78, p=0.013) and open fractures (OR 7.02, psite infection. Operative times approaching 3h and open fractures are related to an increased overall risk for surgical site infection after open plating of the tibial plateau. Dual incision approaches with bicolumnar plating do not appear to expose the patient to increased risk compared to single incision approaches. Copyright © 2012 Elsevier Ltd. All rights reserved.

Non-operative management is superior to surgical stabilization in spine injury patients with complete neurological deficits: A perspective study from a developing world country, Pakistan.

Science.gov (United States)

Shamim, Muhammad Shahzad; Ali, Syed Faizan; Enam, Syed Ather

2011-01-01

Surgical stabilization of injured spine in patients with complete spinal cord injury is a common practice despite the lack of strong evidence supporting it. The aim of this study is to compare clinical outcomes and cost-effectiveness of surgical stabilization versus conservative management of spinal injury in patients with complete deficits, essentially from a developing country's point of view. A detailed analysis of patients with traumatic spine injury and complete deficits admitted at the Aga Khan University Hospital, Pakistan, from January 2004 till January 2010 was carried out. All patients presenting within 14 days of injury were divided in two groups, those who underwent stabilization procedures and those who were managed non-operatively. The two groups were compared with the endpoints being time to rehabilitation, length of hospital stay, 30 day morbidity/mortality, cost of treatment, and status at follow up. Fifty-four patients fulfilled the inclusion criteria and half of these were operated. On comparing endpoints, patients in the operative group took longer time to rehabilitation (P-value = 0.002); had longer hospital stay (P-value = 0.006) which included longer length of stay in special care unit (P-value = 0.002) as well as intensive care unit (P-value = 0.004); and were associated with more complications, especially those related to infections (P-value = 0.002). The mean cost of treatment was also significantly higher in the operative group (USD 6,500) as compared to non-operative group (USD 1490) (P-value managed non-operatively with a provision of surgery only if their rehabilitation is impeded due to pain or deformity.

18 CFR 367.4180 - Account 418, Non-operating rental income.

Science.gov (United States)

2010-04-01

... GAS ACT Income Statement Chart of Accounts Service Company Operating Income § 367.4180 Account 418, Non-operating rental income. (a) The expenses shall include all elements of costs incurred in the...-operating rental income. 367.4180 Section 367.4180 Conservation of Power and Water Resources FEDERAL ENERGY...

Efficacy and influence factors of icotinib hydrochloride in treating advanced non-small cell lung cancer.

Science.gov (United States)

Ma, X-H; Tian, T-D; Liu, H-M; Li, Q-J; Gao, Q-L; Li, L; Shi, B

2017-01-01

To evaluate the efficacy and safety of icotinib hydrochloride in the treatment of patients with advanced non-small cell lung cancer (NSCLC) and discuss the influence factors on efficacy. 120 treatment-experienced patients confirmed by pathology or cytology with stage III B-IV non-small cell lung cancer took icotinib hydrochloride and erlotinib orally until the occurrence of disease progression or serious adverse reactions. Then, the efficacy of icotinib hydrochloride and the related influence factors were analyzed. In icotinib hydrochloride group, the response rate and the disease control rate were 30.00% and 65.00%, and the median progression-free survival time was 179 days (95% CI: 103.21-254.78); in erlotinib group, the response rate and the disease control rate were 25.00% and 56.70%, and the median progression-free survival time was 121 days (95% CI: 95.05-146.94). Moreover, the objective response rate and the disease control rate of second-line therapy were both superior to the third-line and above therapy. The objective response rate of patients with complete response/partial response/stable disease after the first-line therapy was higher than that of patients without response after the first-line therapy (picotinib hydrochloride is effective and safe in treating the treatment-experienced patients with advanced NSCLC, especially for patients with sensitive mutations.

Prognostic factors in non-Hodgkin lymphoma stage I treated with radiotherapy

International Nuclear Information System (INIS)

Hagberg, H.; Pettersson, U.; Glimelius, B.; Sundstroem, C.

1989-01-01

The results of treatment in 175 consecutive patients with non-Hodgkin lymphoma (NHL) clinical stage I treated between 1969 and 1984 were analysed according to different pretreatment prognostic variables. Treatment consisted of radiotherapy in 166 of the 175 patients. The estimated 5 and 10-year disease-free survival rates (DFS) were 63% and 60% and the survival rates at 5 and 10 years 82% and 76% respectively. Lymphomas arising from gut-associated lymphoid tissue, i.e. Waldeyer's ring, the thyroid and the gastrointestinal tract had a more favourable clinical course (10-year projected DFS 83%) than nodal (50%) and other extranodal lymphomas. Although the number of patients with other extranodal sites was small, sites such as testis, nasal cavity, paranasal sinus and extradural space seemed to have a high relapse rate. Unfavourable clinical courses were also observed among nodal high-grade NHL if the lymph nodes were larger than 5 cm in diameter. Chemotherapy before radiotherapy may be recommended in NHL subgroups with a high relapse rate and which today are potentially curable with chemotherapy, i.e. high-grade NHL. This study indicates that large nodal lymphomas and some extranodal sites belong to this group. (orig.)

Prognostic factors in non-Hodgkin lymphoma stage I treated with radiotherapy

Energy Technology Data Exchange (ETDEWEB)

Hagberg, H.; Pettersson, U.; Glimelius, B.; Sundstroem, C.

1989-01-01

The results of treatment in 175 consecutive patients with non-Hodgkin lymphoma (NHL) clinical stage I treated between 1969 and 1984 were analysed according to different pretreatment prognostic variables. Treatment consisted of radiotherapy in 166 of the 175 patients. The estimated 5 and 10-year disease-free survival rates (DFS) were 63% and 60% and the survival rates at 5 and 10 years 82% and 76% respectively. Lymphomas arising from gut-associated lymphoid tissue, i.e. Waldeyer's ring, the thyroid and the gastrointestinal tract had a more favourable clinical course (10-year projected DFS 83%) than nodal (50%) and other extranodal lymphomas. Although the number of patients with other extranodal sites was small, sites such as testis, nasal cavity, paranasal sinus and extradural space seemed to have a high relapse rate. Unfavourable clinical courses were also observed among nodal high-grade NHL if the lymph nodes were larger than 5 cm in diameter. Chemotherapy before radiotherapy may be recommended in NHL subgroups with a high relapse rate and which today are potentially curable with chemotherapy, i.e. high-grade NHL. This study indicates that large nodal lymphomas and some extranodal sites belong to this group. (orig.).

Association between elevated pre-operative glycosylated hemoglobin and post-operative infections after non-emergent surgery

OpenAIRE

Blankush, Joseph M.; Leitman, I. Michael; Soleiman, Aron; Tran, Trung

2016-01-01

Background: A chronic state of impaired glucose metabolism affects multiple components of the immune system, possibly leading to an increased incidence of post-operative infections. Such infections increase morbidity, length of stay, and overall cost. This study evaluates the correlation between elevated pre-operative glycosylated hemoglobin (HbA1c) and post-operative infections. Study design: Adult patients undergoing non-emergent procedures across all surgical subspecialties from January...

Group Approach to the Quantization of Non-Abelian Stueckelberg Models

International Nuclear Information System (INIS)

Aldaya, V; Lopez-Ruiz, F F; Calixto, M

2011-01-01

The quantum field theory of Non-Linear Sigma Models on coadjoint orbits of a semi-simple group G are formulated in the framework of a Group Approach to Quantization. In this scheme, partial-trace Lagrangians are recovered from two-cocycles defined on the infinite-dimensional group of sections of the jet-gauge group J 1 (G). This construction is extended to the entire physical system coupled to Yang-Mills fields, thus constituting an algebraic formulation of the Non-Abelian Stueckelgerg formalism devoid of the unitarity/renormalizability obstruction that this theory finds in the standard Lagrangian formalism under canonical quantization.

Group Approach to the Quantization of Non-Abelian Stueckelberg Models

Energy Technology Data Exchange (ETDEWEB)

Aldaya, V; Lopez-Ruiz, F F [Instituto de Astrofisica de AndalucIa (IAA-CSIC), Apartado Postal 3004, 18080 Granada (Spain); Calixto, M, E-mail: valdaya@iaa.es, E-mail: Manuel.Calixto@upct.es, E-mail: flopez@iaa.es [Departamento de Matematica Aplicada y Estadistica, Universidad Politecnica de Cartagena, Paseo Alfonso XIII 56, 30203 Cartagena (Spain)

2011-03-01

The quantum field theory of Non-Linear Sigma Models on coadjoint orbits of a semi-simple group G are formulated in the framework of a Group Approach to Quantization. In this scheme, partial-trace Lagrangians are recovered from two-cocycles defined on the infinite-dimensional group of sections of the jet-gauge group J{sup 1} (G). This construction is extended to the entire physical system coupled to Yang-Mills fields, thus constituting an algebraic formulation of the Non-Abelian Stueckelgerg formalism devoid of the unitarity/renormalizability obstruction that this theory finds in the standard Lagrangian formalism under canonical quantization.

Neuropsychological evaluation of patients with inoperable non-small cell lung cancer treated with combination chemotherapy or radiotherapy

Energy Technology Data Exchange (ETDEWEB)

Kaasa, S; Olsnes, B T; Mastekaasa, A

1988-01-01

Neuropsychological tests were used to evaluate possible central nervous system dysfunction in patients treated with chemotherapy. Ninety-five patients with non-small cell lung cancer limited disease were randomized to either radiotherapy (2.8 Gyx15) or combination chemotherapy with cisplatin and etoposide. In order to evaluate cognitive functions three neuropsychological tests were applied: Trail Making, Benton Visual Retention Test and Verbal Learning. Changes in the patients' test scores before and after treatment were compared. The chemotherapy patients showed reduced performance on some of the neuropsychological tests compared to the radiotherapy group. This indicates a treatment related effect on the central nervous system, possibly caused by the combination chemotherapy.

Neuropsychological evaluation of patients with inoperable non-small cell lung cancer treated with combination chemotherapy or radiotherapy

International Nuclear Information System (INIS)

Kaasa, S.; Olsnes, B.T.; Mastekaasa, A.

1988-01-01

Neuropsychological tests were used to evaluate possible central nervous system dysfunction in patients treated with chemotherapy. Ninety-five patients with non-small cell lung cancer limited disease were randomized to either radiotherapy (2.8 Gyx15) or combination chemotherapy with cisplatin and etoposide. In order to evaluate cognitive functions three neuropsychological tests were applied: Trail Making, Benton Visual Retention Test and Verbal Learning. Changes in the patients' test scores before and after treatment were compared. The chemotherapy patients showed reduced performance on some of the neuropsychological tests compared to the radiotherapy group. This indicates a treatment related effect on the central nervous system, possibly caused by the combination chemotherapy. (orig.)

Non-commutative analysis

CERN Document Server

Jorgensen, Palle

2017-01-01

The book features new directions in analysis, with an emphasis on Hilbert space, mathematical physics, and stochastic processes. We interpret 'non-commutative analysis' broadly to include representations of non-Abelian groups, and non-Abelian algebras; emphasis on Lie groups and operator algebras (C* algebras and von Neumann algebras.)A second theme is commutative and non-commutative harmonic analysis, spectral theory, operator theory and their applications. The list of topics includes shift invariant spaces, group action in differential geometry, and frame theory (over-complete bases) and their applications to engineering (signal processing and multiplexing), projective multi-resolutions, and free probability algebras.The book serves as an accessible introduction, offering a timeless presentation, attractive and accessible to students, both in mathematics and in neighboring fields.

Non-perturbative versus perturbative renormalization of lattice operators

International Nuclear Information System (INIS)

Goeckeler, M.; Technische Hochschule Aachen; Horsley, R.; Ilgenfritz, E.M.; Oelrich, H.; Forschungszentrum Juelich GmbH; Schierholz, G.; Forschungszentrum Juelich GmbH; Perlt, H.; Schiller, A.; Rakow, P.

1995-09-01

Our objective is to compute the moments of the deep-inelastic structure functions of the nucleon on the lattice. A major source of uncertainty is the renormalization of the lattice operators that enter the calculation. In this talk we compare the renormalization constants of the most relevant twist-two bilinear quark operators which we have computed non-perturbatively and perturbatively to one loop order. Furthermore, we discuss the use of tadpole improved perturbation theory. (orig.)

Brain abnormalities on MRI in non-functioning pituitary adenoma patients treated with or without postoperative radiotherapy

NARCIS (Netherlands)

Sattler, Margriet G. A.; Meiners, Linda C.; Sluiter, Wim J.; van den Berg, Gerrit; Langendijk, Johannes A.; Wolffenbuttel, Bruce H. R.; van den Bergh, Alphons C. M.; van Beek, Andre P.

Background and purpose: To assess and compare brain abnormalities on Magnetic Resonance Imaging (MRI) in non-functioning pituitary macro-adenoma (NFA) patients treated with or without postoperative radiotherapy (RT). Material and methods: In 86 NFA patients, treated between 1987 and 2008 at the

Non-operative anti-caries agents and dental caries increment among adults at high caries risk: a retrospective cohort study.

Science.gov (United States)

Chaffee, Benjamin W; Cheng, Jing; Featherstone, John D B

2015-09-24

Consensus guidelines support non-operative preventives for dental caries management; yet, their use in practice is far from universal. The purpose of this study was to evaluate the effectiveness of non-operative anti-caries agents in caries prevention among high caries risk adults at a university clinic where risk-based caries management is emphasized. This retrospective observational study drew data from the electronic patient records of non-edentulous adult patients deemed to be at high risk for dental caries during baseline oral evaluations that were completed between July 1, 2007 and December 31, 2012 at a dental university in the United States. We calculated and compared adjusted mean estimates for the number of new decayed or restored teeth (DFT increment) from baseline to the next completed oral evaluation (N = 2,724 patients with follow-up) across three categories of delivery of non-operative anti-caries agents (e.g., high-concentration fluoride toothpaste, chlorhexidine rinse, xylitol products): never, at a single appointment, or at ≥2 appointments ≥4 weeks apart. Estimates were adjusted for patient and provider characteristics, baseline dental status, losses-to-follow-up, and follow-up time. Approximately half the patients did not receive any form of non-operative anti-caries agent. Most that received anti-caries agents were given more than one type of product in combination. One-time delivery of anti-caries agents was associated with a similar DFT increment as receiving no such therapy (difference in increment: -0.04; 95% CI: -0.28, 0.21). However, repeated, spaced delivery of anti-caries agents was associated with approximately one decayed or restored tooth prevented over 18 months for every three patients treated (difference in increment: -0.35; 95% CI: -0.65, -0.08). These results lend evidence that repeatedly receiving anti-caries agents can reduce tooth decay among high-risk patients engaged in regular dental care.

Prevalence of right atrial non-pulmonary vein triggers in atrial fibrillation patients treated with thyroid hormone replacement therapy.

Science.gov (United States)

Kim, Ki-Hun; Mohanty, Sanghamitra; Mohanty, Prasant; Trivedi, Chintan; Morris, Eli Hamilton; Santangeli, Pasquale; Bai, Rong; Al-Ahmad, Amin; Burkhardt, John David; Gallinghouse, Joseph G; Horton, Rodney; Sanchez, Javier E; Bailey, Shane; Hranitzky, Patrick M; Zagrodzky, Jason; Kim, Soo G; Di Biase, Luigi; Natale, Andrea

2017-08-01

Thyroid hormone (TH) is known to enhance arrhythmogenicity, and high-normal thyroid function is related with an increased recurrence of atrial fibrillation (AF) after catheter ablation. However, the impact of thyroid hormone replacement (THR) on AF ablation is not well known. This study evaluated 1163 consecutive paroxysmal AF patients [160 (14%) on THR and 1003 (86%) without THR] undergoing their first catheter ablation. A total of 146 patients on THR and 146 controls were generated by propensity matching, based on calculated risk factor scores, using a logistic model (age, sex, body mass index, and left atrium size). The presence of non-pulmonary vein (PV) triggers was disclosed by a high-dose isoproterenol challenge (up to 30 μg/min) after PV isolation. Clinical characteristics were not different between the groups. When compared to the control, non-PV triggers were significantly greater in the THR patients [112 (77%) vs. 47 (32%), P atrial appendage (47 vs. 34%, P = 0.03), crista terminalis/superior vena cava (11 vs. 8%, P = 0.43), and mitral valve annulus (7 vs. 5%, P = 0.45) (THR vs. control), respectively. After mean follow-up of 14.7 ± 5.2 months, success rate was lower in patients on THR therapy [94 (64.4%)] compared to patients not receiving THR therapy [110 (75.3%), log-rank test value = 0.04]. Right atrial non-PV triggers were more prevalent in AF patients treated with THR. Elimination of non-PV triggers provided better arrhythmia-free survival in the non-THR group.

Non-coboundary Poisson–Lie structures on the book group

International Nuclear Information System (INIS)

Ballesteros, Ángel; Blasco, Alfonso; Musso, Fabio

2012-01-01

All possible Poisson–Lie (PL) structures on the 3D real Lie group generated by a dilation and two commuting translations are obtained. Their classification is fully performed by relating these PL groups to the corresponding Lie bialgebra structures on the corresponding ‘book’ Lie algebra. By construction, all these Poisson structures are quadratic Poisson–Hopf algebras for which the group multiplication is a Poisson map. In contrast to the case of simple Lie groups, it turns out that most of the PL structures on the book group are non-coboundary ones. Moreover, from the viewpoint of Poisson dynamics, the most interesting PL book structures are just some of these non-coboundaries, which are explicitly analysed. In particular, we show that the two different q-deformed Poisson versions of the sl(2, R) algebra appear as two distinguished cases in this classification, as well as the quadratic Poisson structure that underlies the integrability of a large class of 3D Lotka–Volterra equations. Finally, the quantization problem for these PL groups is sketched. (paper)

ABOUT COMPLEX OPERATIONS IN NON-POSITIONAL RESIDUE NUMBER SYSTEM

Directory of Open Access Journals (Sweden)

Yu. D. Polissky

2016-04-01

Full Text Available Purpose. The purpose of this work is the theoretical substantiation of methods for increased efficiency of execution of difficult, so-called not modular, operations in non-positional residue number system for which it is necessary to know operand digits for all grade levels. Methodology. To achieve the target the numbers are presented in odd module system, while the result of the operation is determined on the basis of establishing the operand parity. The parity is determined by finding the sum modulo for the values of the number positional characteristics for all of its modules. Algorithm of position characteristics includes two types of iteration. The first iteration is to move from this number to a smaller number, in which the remains of one or more modules are equal to zero. This is achieved by subtracting out of all the residues the value of one of them. The second iteration is to move from this number to a smaller number due to exclusion of modules, which residues are zero, by dividing this number by the product of these modules. Iterations are performed until the residues of one, some or all of the modules equal to zero and other modules are excluded. The proposed method is distinguished by its simplicity and allows you to obtain the result of the operation quickly. Findings. There are obtained rather simple solutions of not modular operations for definition of outputs beyond the range of the result of adding or subtracting pairs of numbers, comparing pairs of numbers, determining the number belonging to the specific half of the range, defining parity of numbers presented in non-positional residue number system. Originality. The work offered the new effective approaches to solve the non-modular operations of the non-positional residue number system. It seems appropriate to consider these approaches as research areas to enhance the effectiveness of the modular calculation. Practical value. The above solutions have high performance and can

The operators' non-compliance behavior to conduct emergency operating procedures--comparing with the work experience and the complexity of procedural steps

International Nuclear Information System (INIS)

Park, Jinkyun; Jung, Wondea

2003-01-01

Many kinds of procedures have been used to reduce the operators' workload throughout various industries, such as in the aviation, the chemical and the nuclear industry. It is remarkable that, however, significant portion of accidents or incidents was caused by procedure related human error due to non-compliance of procedures. In this study, to investigate the operators' non-compliance behavior, emergency-training records were collected using a full scope simulator. And three types of the operators' behavior (such as strict adherence, skipping redundant actions and modifying action sequences) observed from collected emergency training records were compared with both their work experience and the complexity of procedural steps. As the results, three remarkable relationships are obtained. They are: (1) the operators who have an intermediate work experience seem to frequently adopt non-compliance behavior to conduct the procedural steps, (2) the operators seem to frequently adopt non-compliance behavior to conduct the procedural steps that have an intermediate procedural complexity, and (3) the senior reactor operators seem to accommodate their non-compliance behavior based on the complexity of procedural steps. Therefore, it is expected that these relationships can be used as meaningful clues not only to scrutinize the reason for non-compliance behavior but also to suggest appropriate remedies for the reduction of non-compliance behavior that can result in procedure related human error

Multiple-Trace Operators and Non-Local String Theories

International Nuclear Information System (INIS)

Silverstein, Eva M.

2001-01-01

We propose that a novel deformation of string perturbation theory, involving non-local interactions between strings, is required to describe the gravity duals of field theories deformed by multiple-trace operators. The new perturbative expansion involves a new parameter, which is neither the string coupling nor the coefficient of a vertex operator on the worldsheet. We explore some of the properties of this deformation, focusing on a special case where the deformation in the field theory is exactly marginal

Non-unique Product Groups on Two Generators

OpenAIRE

Carter, William Paul

2007-01-01

The main purpose of this paper is to better understand groups that do not have the unique product property. In particular, the goal is to better understand Promislow's example, G, of such a group. In doing so, we will develop methods for generating examples of other sets that do not have the unique product property. With these methods we can show that there exists other distinct 14 element, square, non-unique product sets in G that are not inversions or translations. Also, this paper answers ...

mGluR5 positive allosteric modulation and its effects on MK-801 induced set-shifting impairments in a rat operant delayed matching/non-matching-to-sample task

Science.gov (United States)

LaCrosse, Amber L.; Burrows, Brian T.; Angulo, Rachel M.; Conrad, Phoebe R.; Himes, Sarah M.; Mathews, Nordia; Wegner, Scott A.; Taylor, Sara B.; Olive, M. Foster

2014-01-01

Rationale Positive allosteric modulators (PAMs) of type 5 metabotropic glutamate receptors (mGluR5) exert pro-cognitive effects in animal models of various neuropsychiatric diseases. However, few studies to date have examined ability of mGluR5 PAMs to reverse cognitive deficits in operant delayed matching/non-matching-to-sample (DMS/DNMS) tasks. Objectives To determine the ability of the mGluR5 PAM 3-cyano-N-1,3-diphenyl-1H-pyrazol-5-yl)benzamide (CDPPB) to reverse set-shifting deficits induced by the NMDA receptor antagonist MK-801. Methods Male Sprague-Dawley rats were initially trained to lever press for sucrose reinforcement under either DMS or DNMS conditions. Following successful acquisition of the task, reinforcement conditions were reversed (DNMS→DMS or DMS→DNMS). In Experiment 1, rats were treated daily prior to each session with either vehicle/vehicle, vehicle/MK-801 (0.06 mg/kg) simultaneously, CDPPB (20 mg/kg)/MK-801 simultaneously, or CDPPB 30 min prior to MK-801. In Experiment 2, rats were treated with either vehicle/vehicle, vehicle/MK-801, or CDPPB 30 min prior to MK-801 only prior to sessions that followed task reversal. Results In Experiment 1, no group differences in initial task acquisition were observed. Rats treated with vehicle+MK−801 showed significant set-shifting impairments following task reversal, which were partially attenuated by simultaneous administration of CDPPB/MK-801, and completely precluded by administration of CDPPB 30 min prior to MK-801. In Experiment 2, MK-801 did not impair reversal learning and no other group differences were observed. Conclusions MK-801 induced deficits in operant set-shifting ability were prevented by pretreatment with CDPPB. MK-801 did not produce deficits in initial task learning or when treatment was initiated following task reversal. PMID:24973895

Multi-unit Operations in Non-Nuclear Systems: Lessons Learned for Small Modular Reactors

Energy Technology Data Exchange (ETDEWEB)

OHara J. M.; Higgins, J.; DAgostino, A.

2012-01-17

The nuclear-power community has reached the stage of proposing advanced reactor designs to support power generation for decades to come. Small modular reactors (SMRs) are one approach to meet these energy needs. While the power output of individual reactor modules is relatively small, they can be grouped to produce reactor sites with different outputs. Also, they can be designed to generate hydrogen, or to process heat. Many characteristics of SMRs are quite different from those of current plants and may be operated quite differently. One difference is that multiple units may be operated by a single crew (or a single operator) from one control room. The U.S. Nuclear Regulatory Commission (NRC) is examining the human factors engineering (HFE) aspects of SMRs to support licensing reviews. While we reviewed information on SMR designs to obtain information, the designs are not completed and all of the design and operational information is not yet available. Nor is there information on multi-unit operations as envisioned for SMRs available in operating experience. Thus, to gain a better understanding of multi-unit operations we sought the lesson learned from non-nuclear systems that have experience in multi-unit operations, specifically refineries, unmanned aerial vehicles and tele-intensive care units. In this paper we report the lessons learned from these systems and the implications for SMRs.

Non-fatal self-poisoning across age groups, in Sri Lanka.

Science.gov (United States)

Rajapakse, Thilini; Christensen, Helen; Cotton, Sue; Griffiths, Kathleen Margaret

2016-02-01

Attempted or non-fatal self-poisoning in common in Sri Lanka, but little is known about variation of psychiatric morbidity and suicidal intent across differing ages. The aim of this study was to investigate factors associated with non-fatal self-poisoning in Sri Lanka across three different age groups (namely 14-24 years, 25-34 years and ≥ 35 years). It was anticipated that the findings of the study would inform and guide development of preventive interventions for non-fatal self-poisoning in this country. 935 participants were interviewed within one week of admission to hospital for medical management of non-fatal self-poisoning, over a consecutive 14-month period. Socio-demographic factors, types of poison ingested, triggers and psychiatric morbidity was examined as a function of age. Results showed that a majority (83%) of participants were aged below 35 years. Younger participants aged aged 25-34 years, and ≥ 35 years), who were more likely to ingest pesticides. Recent interpersonal conflict was a proximal trigger seen in all age groups, but suicidal intent, depression and alcohol use disorders increased with age. The overall study findings indicate that most who carry out acts of non-fatal self-poisoning in Sri Lanka are young (aged age groups, but psychiatric morbidity and suicidal intent is higher in the older age groups, as is pesticide ingestion. Age specific interventions may be efficacious in the prevention of non-fatal self-poisoning in Sri Lanka. Copyright © 2016 Elsevier B.V. All rights reserved.

Reduced ferritin levels in individuals with non-O blood group

DEFF Research Database (Denmark)

Rigas, Andreas S; Berkfors, Adam A; Pedersen, Ole B

2017-01-01

stores expressed as ferritin levels. STUDY DESIGN AND METHODS: Ferritin levels were measured at least once for 30,595 Danish Blood Donor Study participants. Linear regression analyses were performed with the ABO blood group as explanatory variable and adjusted for age, number of donations 3 years before......BACKGROUND: Genomewide association studies have reported alleles in the ABO locus to be associated with ferritin levels. These studies warrant the investigation of a possible association between the ABO blood group and ferritin levels. We aimed to explore if ABO blood group is associated with iron...... blood group was associated with a ferritin level of less than 15 ng/mL. RESULTS: Non-O blood group donors had lower ferritin levels than blood group O donors, regardless of sex. Accordingly, risk of ferritin level of less than 15 ng/mL was increased for individuals with non-O blood group compared with O...

Is non-operative management still justified in the treatment of ...

African Journals Online (AJOL)

Abstract. Background: Adhesive small bowel obstruction (ASBO) is a feared complication after abdominal operations in both children and adults. The optimal ... Followup data were available for 29 patients. Demographic ... required surgery. Key words: Adhesive small bowel obstruction, children, non-operative management ...

Factor analysis of financial and operational performance measures of non-profit hospitals.

Science.gov (United States)

Das, Dhiman

2009-01-01

To understand the important dimensions of the financial and operational performance of non-profit hospitals. Secondary data for non-profit US hospitals between 1996 and 2004. I use iterative principal factor analysis of hospitals' financial and operational ratios for each year of the study. For factor interpretation, I use oblique rotation. Financial ratios were created using cost report data from HCRIS 2552-96 available from the Centers for Medicaid & Medicare Services (CMS). I identify five factors--capital structure, profitability, activity, liquidity, and an operational factor--that explain most of the variation in the performance of non-profit hospitals. I also find that capital structure is more important than profitability in determining the performance of these hospitals. The importance of capital structure highlights a significant shift in the organization of the non-profit hospitals' finances.

Five Large Generation Groups:Competing in Capital Operation

Institute of Scientific and Technical Information of China (English)

无

2008-01-01

@@ Since the reform of electric power industry in 2002,the newly established five large generation groups have been persisting in the development strategy of "taking electricity as the core and extending to up-and-downstream businesses." Stringent measures were taken in capital operation and their potential has been shown through electric power assets acquiring,coal and financial resources investing,capital market financing as well as power utility restructuring.The five groups are playing more and more important roles in merger and acquisition (M&A) and capital markets.

42 CFR 52h.3 - Establishment and operation of peer review groups.

Science.gov (United States)

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Establishment and operation of peer review groups... GRANTS SCIENTIFIC PEER REVIEW OF RESEARCH GRANT APPLICATIONS AND RESEARCH AND DEVELOPMENT CONTRACT PROJECTS § 52h.3 Establishment and operation of peer review groups. (a) To the extent applicable, the...

Classification of non-solvable groups with a given property

Indian Academy of Sciences (India)

In this paper, we classify the finite non-solvable groups satisfying the following property P 5 : their orders of representatives are set-wise relatively prime for any 5 distinct non-central conjugacy classes. Author Affiliations. Zeinab Foruzanfar1 Zohreh Mostaghim1. School of Mathematics, Iran University of Science and ...

[Antibacterial prevention of suppurative complications after operations on the large intestine].

Science.gov (United States)

Kuzin, M I; Pomelov, V S; Vandiaev, G K; Ialgashev, T Ia; Blatun, L A

1983-05-01

The data on comparative study of complications after operations on the large intestine are presented. During the preoperative period, 62 patients of the control group were treated with phthalylsulfathiazole, nevigramon and nystatin. Thirty-nine patients of the test group were treated with metronidazole and kanamycin monosulfate. Kanamycin monosulfate was used 3 days before the operation in a dose of 0.5 g orally 4 times a day whereas metronidazole in a dose of 0.5 g 3 times a day. The last doses of the drugs were administered 4-5 hours before the operation. After the operations the patients were treated with kanamycin sulfate for 3-5 days in a daily dose of 2 g intramuscularly. The number of the postoperative suppurative complications decreased from 22 to 5 per cent. No lethal outcomes were registered in the test group. The number of lethal outcomes in the control group amounted to 8 per cent.

Long-term follow-up of otitis media with effusion in children: comparisons between a ventilation tube group and a non-ventilation tube group.

Science.gov (United States)

Hong, Hye Ran; Kim, Tae Su; Chung, Jong Woo

2014-06-01

The objective of this study was to investigate the long-term outcomes in children with otitis media with effusion who received either medical treatment or ventilation tubes. We retrospectively analyzed the medical records of 89 bilateral cases of otitis media with effusion in children who were recommended to receive ventilation tube insertion and were followed up for more than 5 years. Tympanic membrane was inspected by otoscopic examination. Hearing was evaluated with pure tone audiometry. The mean duration of follow-up was 8.4 years (range, 5.2-15.7 years). Twenty-three children were treated without surgery, while 22 were treated once by ventilation tube insertion and 44 were treated more than once by ventilation tube insertion. At the fifth year of follow-up, both groups of children who underwent ventilation tube insertion had more frequent tympanic membrane abnormalities than the medication group (8.7% in those treated without surgery, 72.7% in those treated once by ventilation tube insertion, and 88.6% in those treated more than once by ventilation tube insertion). Common tympanic membrane abnormalities were retraction (27.0%) and tympanosclerotic plaque (23.6%), regardless of the treatment modality. At the fifth year follow-up, the average air-conduction threshold was 10.0 dB (± 6.5 dB) in patients treated without surgery, 15.9 dB (± 11.2dB) in patients treated once by ventilation tube insertion, and 17.8 dB (± 7.6 dB) in those treated more than once by ventilation tube insertion. The audiological difference was significant when we compared the hearing level of children treated by medication without surgery to the two ventilation tube groups. Though ventilation tube insertion can resolve hearing loss quickly, there were more tympanic membrane abnormalities and a decline in hearing levels in our ventilation tube insertion group vs. the observation group measured 5 years later. Physicians should therefore be cautious when applying a ventilation tube in

Non-dipper treated hypertensive patients do not have increased cardiac structural alterations

Directory of Open Access Journals (Sweden)

Magrini Fabio

2003-02-01

Full Text Available Abstract Background Non-dipping pattern in hypertensive patients has been shown to be associated with an excess of target organ damage and with an adverse outcome. The aim of our study was to assess whether a reduced nocturnal fall in blood pressure (BP, established on the basis of a single 24-h BP monitoring, in treated essential hypertensives is related to more prominent cardiac alterations. Methods We enrrolled 229 treated hypertensive patients attending the out-patient clinic of our hypertension centre; each patient was subjected to the following procedures : 1 clinic BP measurement; 2 blood and urine sampling for routine blood chemistry and urine examination; 3 standard 12-lead electrocardiogram; 4 echocardiography; 5 ambulatory BP monitoring (ABPM. For the purpose of this study ABPM was carried-out in three subgroups with different clinic BP profile : 1 patients with satisfactory BP control (BP 2 in men and 110 g/m2 in women, ≥51/gm2.7 in men and 47/g/m2.7 in women. Results Of the 229 study participants 119 (51.9% showed a fall in SBP/DBP Conclusions In treated essential hypertensives with or without BP control the extent of nocturnal BP decrease is not associated with an increase in LV mass or LVH prevalence; therefore, the non-dipping profile, diagnosed on the basis of a single ABPM, does not identify hypertensive patients with greater cardiac damage.

Anti-adhesion barrier gels following operative hysteroscopy for treating female infertility: a systematic review and meta-analysis

NARCIS (Netherlands)

Bosteels, Jan; Weyers, Steven; Mol, Ben W. J.; D'Hooghe, Thomas

2014-01-01

The aim of this study was to assess the effects of any anti-adhesion barrier gel used after operative hysteroscopy for treating infertility associated with uterine cavity abnormalities. Gynecologists might use any barrier gel following operative hysteroscopy in infertile women for decreasing de novo

Pre-operative radiochemotherapy of locally advanced rectal cancer

Institute of Scientific and Technical Information of China (English)

Xiao-Nan Sun; Qi-Chu Yang; Jian-Bin Hu

2003-01-01

AIM: To evaluate results of pre-operative radiochemotherapy followed by surgery for 15 patients with locally advanced un-resectable rectal cancer.METHODS: 15 patients with advanced non-resectable rectal cancer were treated with pre-operative irriadiation of 40-46 Gy plus concomitant chemotherapy (5-FU+LV and 5′-DFuR) (RCS group). For comparison, 27 similar patients,treated by preoperative radiotherapy (40-50 Gy) plus surgery were served as control (RS group).RESULTS: No radiochemotherapy or radiotherapy was interrupted and then was delayed because of toxicities in both groups. The radical resectability rate was 73.3% in the RCS group and 37.0% (P=0.024) in RS group. Sphincter preservation rates were 26.6% and 3.7% respectively (P=0.028). Sphincter preservation rates of lower rectal cancer were 27.3 % and 0.0 % respectively (P=0.014). Response rates of RCS and RS groups were 46.7 % and 18.5 %(P=0.053). The tumor downstage rates were 8 (53.3%)and 9 (33.3%) in these groups (P=0.206). The 3-year overall survival rates were 66.7 % and 55.6% (P=0.485), and the disease free survival rates were 40.1% and 33.2%(P=0.663). The 3-year local recurrent rates were 26.7%and 48.1% (P=0.174). No obvious late effects were found in either groups.CONCLUSION: High resectability is possible following preoperative radiochemotherapy and can have more sphincters preserved. It is important to improve the quality of the patients′ life even without increasing the survival or local control rates. Preoperative radiotherapy with concomitant full course chemotherapy (5-Fu+LV and 5′-DFuR) is effective and safe.

On Subgroups of Non-Commutative General Rhotrix Group ...

African Journals Online (AJOL)

This paper considers the pair (GRn(F),o) consisting of the set of all invertible rhotrices of size n over an arbitrary field F; and together with the binary operation of row-column based method for rhotrix multiplication; 'o' , in order to introduce it as the concept of “non commutative general rhotrix group”. We identify a number of ...

Case Report: A Non-small Cell Lung Cancer Patient Treated with GcMAF, Sonodynamic Therapy and Tumor Treating Fields.

Science.gov (United States)

Inui, Toshio; Amitani, Haruka; Kubo, Kentaro; Kuchiike, Daisuke; Uto, Yoshihiro; Nishikata, Takahito; Mette, Martin

2016-07-01

Macrophage activating factor (MAF)-based immunotherapy has a wide application for use in treating many diseases via macrophage activation. Sonodynamic therapy (SDT) using low-intensity ultrasound and tumor treating field (TTF) therapy are novel therapeutic modalities. SDT is usually combined with ozone therapy to improve local hypoxia within the tumor environment. We treated a 77-year-old male diagnosed with non-small cell lung cancer ((NSCLC) stage 3B) using second-generation serum GcMAF and oral colostrum MAF-based immunotherapy combined with SDT, TTF and ozone therapies. This case report demonstrates that GcMAF, oral colostrum MAF, SDT, TTF and ozone therapy can be used for NSCLC without adverse effects. This case report suggests a new concept of cancer treatment using local destruction of cancer tissue, in this case conducted with SDT and TTF therapy, to be used in combination with serum GcMAF and colostrum MAF immunotherapy as a systemic treatment. Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

Preliminary clinical study on non-transecting anastomotic bulbomembranous urethroplasty.

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Le, Wei; Li, Chao; Zhang, Jinfu; Wu, Denglong; Liu, Bo

2017-06-01

This study aims to investigate the effect of non-transecting anastomotic urethroplasty for treatment of posterior urethral stricture. A total of 23 patients with traumatic posterior urethral stricture were enrolled and then divided into two groups. In one group, 12 patients underwent non-transecting anastomotic urethroplasty. In the other group, 11 patients underwent conventional posterior urethra end-to-end anastomosis. The effect of operation was evaluated using the following parameters: the bleeding amount during operation, operation time, IIEF-5 scores after operation, maximum flow rate (Qmax), and rating scale of quality of life (QoL). The comparison between the conventional posterior urethra end-to-end anastomosis group and the non-transecting anastomotic urethroplasty group showed no significant difference with regard to average operation time. However, a significant difference was observed between the groups with regard to the bleeding amount during operation. The patients in the group of non-transecting anastomotic urethroplasty urinated smoothly after the removal of catheter. Meanwhile, one patient from the group of conventional posterior urethra end-to-end anastomosis had difficulty urinating after the removal of catheter. Furthermore, significant differences in the operation time, bleeding amount during operation, IIEF-5 scores after operation, and rating scale of QoL were observed, whereas no significant difference was observed between urine flow rates of the two groups after operation. Overall, nontransecting anastomotic urethroplasty is effective for posterior urethra reconstruction, and it can reduce the occurrence rate of erectile dysfunction after operation.

Self-monitoring of Blood Glucose in Non-Insulin Treated Type 2 Diabetes (The SMBG Study): study protocol for a randomised controlled trial.

Science.gov (United States)

Parsons, Sharon; Luzio, Stephen; Bain, Stephen; Harvey, John; McKenna, Jillian; Khan, Atir; Rice, Sam; Watkins, Alan; Owens, David R

2017-01-26

The benefit of Self-monitoring of Blood Glucose (SMBG) in people with non-insulin treated type 2 diabetes remains unclear with inconsistent evidence from randomised controlled trials fuelling the continued debate. Lack of a consistent finding has been attributed to variations in study population and design, including the SMBG intervention. There is a growing consensus that structured SMBG, whereby the person with diabetes and health care provider are educated to detect patterns of glycaemic abnormality and take appropriate action according to the blood glucose profiles, can prove beneficial in terms of lowering HbA1c and improving overall well-being. Despite this, many national health agencies continue to issue guidelines restricting the use of SMBG in non-insulin treated type 2 diabetes. The SMBG Study is a 12 month, multi-centre, randomised controlled trial in people with type 2 diabetes not on insulin therapy who have poor glycaemic control (HbA1c ≥58 mmol/mol / 7.5%). The participants will be randomised into three comparative groups: Group 1 will act as a control group and receive their usual diabetes care; Group 2 will undertake structured SMBG with clinical review every 3 months; Group 3 will undertake structured SMBG with additional monthly telecare support from a trained study nurse. A total of 450 participants will be recruited from 16 primary and secondary care sites across Wales and England. The primary outcome measure will be HbA1c at 12 months with secondary measures to include weight, BMI, total cholesterol and HbA1c levels at 3, 6, 9 and 12 months. Participant well-being and attitude towards SMBG will be monitored throughout the course of the study. Recruitment began in December 2012 with the last participant visit due in September 2016. This study will attempt to answer the question of whether structured SMBG provides any benefits to people with poorly controlled type 2 diabetes who are not being treated with insulin. The data will also

[Observation on analgesia effect of electroacupuncture during gynecologic outpatient operation].

Science.gov (United States)

Wang, Xiao-Hui; Wu, Xue-Lei; Jin, Ping-Lin; Wang, Lu-Dong; Zhao, Zhi-En; Qin, Xue-Yu; Zhang, Zhi-Yan; Hu, Xue-Zhu; Cai, Zhen-Lin

2012-10-01

To verify the feasibility of electroacupuncture analgesia applied to gynecologic outpatient operation. Two hundred patients were randomly divided into an electroacupuncture analgesia group and an intravenous anesthesia group, 100 cases in each group. Operation types included artificial abortion, diagnostic curettage and remove of intrauterine divice. The electroacupuncture analgesia group was treated with electroacupuncture at bilateral Hegu (LI 4) and Neiguan (PC 6), and the routine gynecologic outpatient operation was performed under patients' waking state. The intravenous anesthesia group was treated with routine gynecologic outpatient operation after intravenous injection of fentanyl and propofol. The excellent rate and the effective rate of analgesia were 88.0% (88/100) and 100.0% (100/100) in the electroacupuncture analgesia group, and 94.0% (94/100) and 100.0% (100/100) in the intravenous anesthesia group, with no statistically significant differences between the two groups (all P > 0.05). There was no adverse reaction in the electroacupuncture anesthesia group, but 11 cases of adverse reactions in the intravenous anesthesia group. Electroacupuncture analgesia can effectively alleviate the pain during gynecologic outpatient operation and it is simple and safe without adverse reactions.

Non-proliferation through effective international control. Report of working group I

International Nuclear Information System (INIS)

Miller, S.E.

1993-01-01

Working Group I focused on two issues: the nuclear non-proliferation regime and the Missile Technology Regime (MTCR). There was wide agreement within the Group on a number of factors that will strongly influence the prospects for the Non-proliferation Treaty (NPT) extension Conference. Two points stood out as particularly important: first, emphasis on the obligations for nuclear Powers to move in good faith in direction of nuclear disarmament; and second, inadequacy of security guarantees to non-nuclear States associated with the NPT

Joint-operation in water resources project in Indonesia: Integrated or non-integrated

Science.gov (United States)

Ophiyandri, Taufika; Istijono, Bambang; Hidayat, Benny

2017-11-01

The construction of large water resources infrastructure project often involved a joint-operation (JO) project between two or more construction companies. The form of JO can be grouped into two categories - an integrated type and a non-integrated type. This paper investigates the reason of forming a JO project made by companies. The specific advantages and problems of JO project is also analysed in this paper. In order to achieve the objectives, three water resources infrastructure projects were selected as case studies. Data was gathered by conducting 11 semi-structured interviews to project owners, contractor managers, and project staffs. Data was analysed by means of content analysis. It was found that the most fundamental factor to form a JO is to win a competition or tender. An integrated model is in favour because it can reduce overhead costs and has a simple management system, while a non-integrated model is selected because it can avoid a sleeping partner and make contractor more responsible for their own job.

Analysis of prognostic factors in patients with non-small cell lung cancer treated conventional radical teleradiotherapy

International Nuclear Information System (INIS)

Pluta, E.

2007-01-01

Radical surgery is the treatment of choice in non-small cell lung cancer, however, only about 20-30% of patients with early stage of disease (stage I, II and possibly IIIA) qualify for it. For the remaining patients, unable to tolerate surgery because of underlying medial disease, advanced age, respiratory insufficiency, or those who refused to undergo operation, radiation therapy is a clinically accepted alternative. Five - year survival for patients receiving radical radiation treatment alone ranges from 12-32%. We reviewed the records of 227 patients with inoperable non-small cell lung cancer, treated in our Institute between 1970-1990. In our group: 40% patients have unresectable tumor, 21% had bad pulmonary function tests results, 15% had cardiac risk, 6% were over 76 years of age, and 18% refused to agree to surgery. Treatment was delivered using megavoltage irradiation in doses ranging from 60 to 72 Gy. The survival probability was calculated by the Kaplan-Meier method. Overall survival (OS) probability at two years was 34% and at five years - 10%. Two - years local control was observed in 54% and five-year in 41%. The disease - specific survival (DSS) rates at 2 and 5 years were 30% and 8% respectively. The significant favorable prognostic factor for DSS and OS were tumor size (T1,T2, N0) and early stage (I), no weight loss, and complete radiological regression of the tumor 8 weeks after irradiation. The significant favorable prognostic factors for local control were good performance status (over 80 points acc. to Karnofsky scale), no weight loss, early stage (I), and complete radiological regression of the tumor 8 weeks after irradiation. 1. New therapeutic strategies involving chemotherapy should be considered for larger tumors (T2, T3, N1, N2). 2. Patients with a good performance status and small tumor (T1N0, T2N0) would benefit most from treatment with radiation alone. (author)

Failure patterns by prognostic group as determined by recursive partitioning analysis (RPA) of 1547 on four radiation therapy oncology group studies in operable non-small cell lung cancer (NSCLC)

International Nuclear Information System (INIS)

Komaki, Ritsuko; Scott, Charles B.; Byhardt, Roger W.; Emami, Bahman; Asbell, Sucha O.; Russell, Anthony H.; Roach, Mack; Urtasun, Raul C.; Gaspar, Laurie E.

1997-01-01

Purpose: To identify groups of patients who might benefit from more aggressive systemic or local treatment based on failure patterns when unresectable NSCLC was treated by radiation therapy alone. Methods: 1547 patients from 4 RTOG trials treated by RT alone were analyzed for the patterns of first failure by PRA class which was defined by prognostic factors, e.g., stage, KPS, weight loss, pleural effusion, age. All patients were AJCC stage II, IIIA or IIIB with KPS of at least 50 and n previous radiotherapy or chemotherapy for their NSCLC. Progressions in the primary (within irradiated fields), thorax (outside irradiated area), brain and distant metastasis other than brain were compared (two-sided) for each failure category by RPA. Results: The RPA classes are four distinct subgroups that had significantly different median survivals of 12.6, 8.3, 6.2 and 3.3 months for classes I, II, III and IV respectively (all groups p=0.0002). Pair comparison showed that RPA I vs IV p<0.0001, I vs III p=0.006, II vs IV p<0.0001, and III vs IV p=0.06. Conclusions: These results suggest the burden of disease and physiologic compromise in class IV patients are sufficient to cause death before specific sites of failure can be discerned. Site specific treatment strategies (intensive local therapy, combination chemotherapy, prophylactic cranial irradiation) may lead to improved outcome in class I and II, but are unlikely to alter outcome in class III and IV

Predictive Accuracy of Violence Risk Scale-Sexual Offender Version Risk and Change Scores in Treated Canadian Aboriginal and Non-Aboriginal Sexual Offenders.

Science.gov (United States)

Olver, Mark E; Sowden, Justina N; Kingston, Drew A; Nicholaichuk, Terry P; Gordon, Audrey; Beggs Christofferson, Sarah M; Wong, Stephen C P

2018-04-01

The present study examined the predictive properties of Violence Risk Scale-Sexual Offender version (VRS-SO) risk and change scores among Aboriginal and non-Aboriginal sexual offenders in a combined sample of 1,063 Canadian federally incarcerated men. All men participated in sexual offender treatment programming through the Correctional Service of Canada (CSC) at sites across its five regions. The Static-99R was also examined for comparison purposes. In total, 393 of the men were identified as Aboriginal (i.e., First Nations, Métis, Circumpolar) while 670 were non-Aboriginal and primarily White. Aboriginal men scored significantly higher on the Static-99R and VRS-SO and had higher rates of sexual and violent recidivism; however, there were no significant differences between Aboriginal and non-Aboriginal groups on treatment change with both groups demonstrating close to a half-standard deviation of change pre and post treatment. VRS-SO risk and change scores significantly predicted sexual and violent recidivism over fixed 5- and 10-year follow-ups for both racial/ancestral groups. Cox regression survival analyses also demonstrated positive treatment changes to be significantly associated with reductions in sexual and violent recidivism among Aboriginal and non-Aboriginal men after controlling baseline risk. A series of follow-up Cox regression analyses demonstrated that risk and change score information accounted for much of the observed differences between Aboriginal and non-Aboriginal men in rates of sexual recidivism; however, marked group differences persisted in rates of general violent recidivism even after controlling for these covariates. The results support the predictive properties of VRS-SO risk and change scores with treated Canadian Aboriginal sexual offenders.

Predictive potential of pre-operative functional neuroimaging in patients treated with subthalamic stimulation

International Nuclear Information System (INIS)

Sestini, Stelvio; Castagnoli, Antonio; Pupi, Alberto; Sciagra, Roberto; Ammannati, Franco; Ramat, Silvia; Sorbi, Sandro; Mansi, Luigi

2010-01-01

The aim of this study was to investigate the predictive potential of pre-operative regional cerebral blood flow (rCBF) in the pre-supplementary motor area (pre-SMA) and clinical factors in Parkinson's disease (PD) patients treated with subthalamic nucleus (STN) stimulation. Ten patients underwent rCBF SPECT and motor Unified Parkinson's Disease Rating Scale (UPDRS) pre- and post-operatively during stimulation at 5 and 42 months. Statistical parametric mapping (SPM) was used to extract rCBF values in the pre-SMA because it is related with motor improvement. Post-operative outcomes included motor response to stimulation and percent improvement in UPDRS. Pre-operative predictors were explored by correlation test, linear regression and multivariate analyses. Higher pre-operative rCBF in the pre-SMA and younger age were associated with favourable outcomes at 5 and 42 months. Pre-operative rCBF results were significantly associated with baseline clinical factors. This study shows that PD patients with younger age have higher rCBF values in the pre-SMA and better outcome, thus giving the rationale to the hypothesis that STN stimulation could be considered early in the course of disease. (orig.)

Predictive potential of pre-operative functional neuroimaging in patients treated with subthalamic stimulation

Energy Technology Data Exchange (ETDEWEB)

Sestini, Stelvio; Castagnoli, Antonio [Ospedale Misericordia e Dolce, Department of Diagnostic Imaging, Nuclear Medicine Unit, Prato (Italy); Pupi, Alberto; Sciagra, Roberto [University of Florence, Department of Clinical Physiopathology, Nuclear Medicine Unit, Florence (Italy); Ammannati, Franco; Ramat, Silvia; Sorbi, Sandro [University of Florence, Department of Neurological and Psychiatric Sciences, Florence (Italy); Mansi, Luigi [University II Naples, Department of Diagnostic Imaging, Nuclear Medicine Unit, Naples (Italy)

2010-01-15

The aim of this study was to investigate the predictive potential of pre-operative regional cerebral blood flow (rCBF) in the pre-supplementary motor area (pre-SMA) and clinical factors in Parkinson's disease (PD) patients treated with subthalamic nucleus (STN) stimulation. Ten patients underwent rCBF SPECT and motor Unified Parkinson's Disease Rating Scale (UPDRS) pre- and post-operatively during stimulation at 5 and 42 months. Statistical parametric mapping (SPM) was used to extract rCBF values in the pre-SMA because it is related with motor improvement. Post-operative outcomes included motor response to stimulation and percent improvement in UPDRS. Pre-operative predictors were explored by correlation test, linear regression and multivariate analyses. Higher pre-operative rCBF in the pre-SMA and younger age were associated with favourable outcomes at 5 and 42 months. Pre-operative rCBF results were significantly associated with baseline clinical factors. This study shows that PD patients with younger age have higher rCBF values in the pre-SMA and better outcome, thus giving the rationale to the hypothesis that STN stimulation could be considered early in the course of disease. (orig.)

Aerial Application of Acetaminophen treated Baits for Control of Brown Treesnakes

Science.gov (United States)

2016-01-22

This procedure followed NWRC Analytical Method 96B -Determination of Acetaminophen in Tablets. Brown tree snake and non-target animal carcasses ...274 viii ACRONYM LIST APHIS Animal and Plant Health Inspection Service ATOC Aviation and Training Operations Center...native rodent abundance, and impacts to non-target animals . TECHNOLOGY DESCRIPTION Thawed DNM were treated by inserting an 80 mg acetaminophen

[Comparison of the Efficacy and Safety of Icotinib with Standard Second-line 
Chemotherapy in Previously Treated Advanced Non-small Cell Lung Cancer].

Science.gov (United States)

Yao, Shuyang; Qian, Kun; Wang, Ruotian; Li, Yuanbo; Zhang, Yi

2015-06-01

This study compared the efficacy and safety of icotinib with standard second-line chemotherapy (single-agent docetaxel or pemetrexed) in previously treated advanced non-small cell lung cancer (NSCLC). Thirty-two consecutive patients treated with icotinib and 33 consecutive patients treated with standard second-line chemotherapy in Xuanwu Hospital from January 2012 to July 2013 were enrolled in our retrospective research. The Response Evaluation Criteria in Solid Tumors were used to evaluate the tumor responses, and the progression-free survival (PFS) was evaluated by Kaplan-Meier method. Icotinib was comparable with standard second-line chemotherapy for advanced NSCLC in terms of overall response rate (ORR) (28.1% vs 18.2%, P=0.341), disease control rate (DFS)(43.8% vs 45.5%, P=0.890), and PFS (4.3 months vs 3.8 months, P=0.506). In the icotinib group, the ORR of epidermal growth factor receptor (EGFR) mutant was significantly higher than that of EGFR unknown or wild type (P=0.017). In multivariate analysis, age, gender, histology, and the optimum first-line treatment response were dependent prognostic factors based on the PFS of the icotinib group. The incidence of adverse events was significantly fewer in the icotinib group than in the chemotherapy group (P=0.001). Compared with the standard second-line chemotherapy, icotinib is active in the treatment of advanced NSCLC patients, especially with EGFR unknown in the second line, with an acceptable adverse event profile.

Real-time reservoir operation considering non-stationary inflow prediction

Science.gov (United States)

Zhao, J.; Xu, W.; Cai, X.; Wang, Z.

2011-12-01

Stationarity of inflow has been a basic assumption for reservoir operation rule design, which is now facing challenges due to climate change and human interferences. This paper proposes a modeling framework to incorporate non-stationary inflow prediction for optimizing the hedging operation rule of large reservoirs with multiple-year flow regulation capacity. A multi-stage optimization model is formulated and a solution algorithm based on the optimality conditions is developed to incorporate non-stationary annual inflow prediction through a rolling, dynamic framework that updates the prediction from period to period and adopt the updated prediction in reservoir operation decision. The prediction model is ARIMA(4,1,0), in which parameter 4 stands for the order of autoregressive, 1 represents a linear trend, and 0 is the order of moving average. The modeling framework and solution algorithm is applied to the Miyun reservoir in China, determining a yearly operating schedule during the period from 1996 to 2009, during which there was a significant declining trend of reservoir inflow. Different operation policy scenarios are modeled, including standard operation policy (SOP, matching the current demand as much as possible), hedging rule (i.e., leaving a certain amount of water for future to avoid large risk of water deficit) with forecast from ARIMA (HR-1), hedging (HR) with perfect forecast (HR-2 ). Compared to the results of these scenarios to that of the actual reservoir operation (AO), the utility of the reservoir operation under HR-1 is 3.0% lower than HR-2, but 3.7% higher than the AO and 14.4% higher than SOP. Note that the utility under AO is 10.3% higher than that under SOP, which shows that a certain level of hedging under some inflow prediction or forecast was used in the real-world operation. Moreover, the impacts of discount rate and forecast uncertainty level on the operation will be discussed.

Group actions, non-Kähler complex manifolds and SKT structures

Directory of Open Access Journals (Sweden)

Poddar Mainak

2018-02-01

Full Text Available We give a construction of integrable complex structures on the total space of a smooth principal bundle over a complex manifold, with an even dimensional compact Lie group as structure group, under certain conditions. This generalizes the constructions of complex structure on compact Lie groups by Samelson and Wang, and on principal torus bundles by Calabi-Eckmann and others. It also yields large classes of new examples of non-Kähler compact complex manifolds. Moreover, under suitable restrictions on the base manifold, the structure group, and characteristic classes, the total space of the principal bundle admits SKT metrics. This generalizes recent results of Grantcharov et al. We study the Picard group and the algebraic dimension of the total space in some cases. We also use a slightly generalized version of the construction to obtain (non-Kähler complex structures on tangential frame bundles of complex orbifolds.

The effects of various physical non-operative modalities on the pain in osteoarthritis of the knee.

Science.gov (United States)

Cherian, J J; Jauregui, J J; Leichliter, A K; Elmallah, R K; Bhave, A; Mont, M A

2016-01-01

The purpose of this study was to evaluate the effect of various non-operative modalities of treatment (transcutaneous electrical nerve stimulation (TENS); neuromuscular electrical stimulation (NMES); insoles and bracing) on the pain of osteoarthritis (OA) of the knee. We conducted a systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to identify the therapeutic options which are commonly adopted for the management of osteoarthritis (OA) of the knee. The outcome measurement tools used in the different studies were the visual analogue scale and The Western Ontario and McMaster Universities Arthritis Index pain index: all pain scores were converted to a 100-point scale. A total of 30 studies met our inclusion criteria: 13 on insoles, seven on TENS, six on NMES, and four on bracing. The standardised mean difference (SMD) in pain after treatment with TENS was 1.796, which represented a significant reduction in pain. The significant overall effect estimate for NMES on pain was similar to that of TENS, with a SMD of 1.924. The overall effect estimate of insoles on pain was a SMD of 0.992. The overall effect of bracing showed a significant reduction in pain of 1.34. Overall, all four non-operative modalities of treatment were found to have a significant effect on the reduction of pain in OA of the knee. This study shows that non-operative physical modalities of treatment are of benefit when treating OA of the knee. However, much of the literature reviewed evaluates studies with follow-up of less than six months: future work should aim to evaluate patients with longer follow-up. ©2016 The British Editorial Society of Bone & Joint Surgery.

Semi-groups of operators and some of their applications to partial differential equations

International Nuclear Information System (INIS)

Kisynski, J.

1976-01-01

Basic notions and theorems of the theory of one-parameter semi-groups of linear operators are given, illustrated by some examples concerned with linear partial differential operators. For brevity, some important and widely developed parts of the semi-group theory such as the general theory of holomorphic semi-groups or the theory of temporally inhomogeneous evolution equations are omitted. This omission includes also the very important application of semi-groups to investigating stochastic processes. (author)

Interactive affective sharing versus non-interactive affective sharing in work groups : Comparative effects of group affect on work group performance and dynamics

NARCIS (Netherlands)

Klep, Annefloor; Wisse, Barbara; Van Der Flier, Henk

This study explores whether the dynamic path to group affect, which is characterized by interactive affective sharing processes, yields different effects on task performance and group dynamics than the static path to group affect, which arises from non-interactive affective sharing. The results of

Interactive affective sharing versus non-interactive affective sharing in work groups: Comparative effects of group affect on work group performance and dynamics

NARCIS (Netherlands)

Klep, A.H.M.; Wisse, B.M.; van der Flier, H.

2011-01-01

This study explores whether the dynamic path to group affect, which is characterized by interactive affective sharing processes, yields different effects on task performance and group dynamics than the static path to group affect, which arises from non-interactive affective sharing. The results of

Non-technical skills of the operating theatre scrub nurse: literature review.

Science.gov (United States)

Mitchell, Lucy; Flin, Rhona

2008-07-01

This paper is a report of a review to identify the non-technical (cognitive and social) skills used by scrub nurses. Recognition that failures in non-technical skills contributed to accidents in high-risk industries led to the development of research programmes to study the role of cognition and social interactions in operational safety. Recently, psychological research in operating theatres has revealed the importance of non-technical skills in safe and efficient performance. Most of the studies to date have focused on anaesthetists and surgeons. On-line sources and university library catalogues, publications of the Association for Perioperative Practice, National Association of Theatre Nurses and Association of Peri-Operative Registered Nurses were searched in 2007. Studies were included in the review if they presented data from scrub nurses on one or more of their non-technical skills. These findings were examined in relation to an existing medical non-technical skills framework with categories of communication, teamwork, leadership, situation awareness and decision-making. Of 424 publications retrieved, 13 were reviewed in detail. Ten concerned communication and eight of those also had data on teamwork. In 11 papers teamwork was examined, and one focused on nurses' situation awareness, teamwork and communication. None of the papers we reviewed examined leadership or decision-making by scrub nurses. Further work is needed to identify formally the non-technical skills which are important to the role of scrub nurse and then to design training in the identified non-technical skills during the education and development of scrub nurses.

Non-transboundary pollution and the efficiency of international environmental co-operation

International Nuclear Information System (INIS)

Kox, Henk L.M.; Van der Tak, Casper M.

1996-01-01

The standard view is that situations where no transborder environmental externalities occur are most efficiently dealt with by national environmental policies rather than by international co-operation. Though this may be the general case, non-coordinated national policies do not always produce the most efficient international allocation. This paper presents four cases in which the allocative outcome of non-coordinated domestic policy choices can be improved upon by international environmental co-operation. The first case refers to the use of environmental policy as a strategic trade instrument. The other cases refer to the existence of discrete technologies, set-up costs and increasing returns to scale. The form of international environmental co-operation should be adapted to the situation. Formal international agreements between countries are characterised by high transaction costs and may not always be the most efficient form of co-operation

4th International Conference on Condition Monitoring of Machinery in Non-Stationary Operations

CERN Document Server

Zimroz, Radoslaw; Bartelmus, Walter; Haddar, Mohamed

2016-01-01

The book provides readers with a snapshot of recent research and technological trends in the field of condition monitoring of machinery working under a broad range of operating conditions. Each chapter, accepted after a rigorous peer-review process, reports on an original piece of work presented and discussed at the 4th International Conference on Condition Monitoring of Machinery in Non-stationary Operations, CMMNO 2014, held on December 15-16, 2014, in Lyon, France. The contributions have been grouped into three different sections according to the main subfield (signal processing, data mining, or condition monitoring techniques) they are related to. The book includes both theoretical developments as well as a number of industrial case studies, in different areas including, but not limited to: noise and vibration; vibro-acoustic diagnosis; signal processing techniques; diagnostic data analysis; instantaneous speed identification; monitoring and diagnostic systems; and dynamic and fault modeling. This book no...

On the Similarity of Sturm-Liouville Operators with Non-Hermitian Boundary Conditions to Self-Adjoint and Normal Operators

Czech Academy of Sciences Publication Activity Database

Krejčiřík, David; Siegl, Petr; Železný, Jakub

2014-01-01

Roč. 8, č. 1 (2014), s. 255-281 ISSN 1661-8254 R&D Projects: GA MŠk LC06002; GA MŠk LC527; GA ČR GAP203/11/0701 Grant - others:GA ČR(CZ) GD202/08/H072 Institutional support: RVO:61389005 Keywords : Sturm-Liouville operators * non-symmetric Robin boundary conditions * similarity to normal or self-adjoint operators * discrete spectral operator * complex symmetric operator * PT-symmetry * metric operator * C operator * Hilbert- Schmidt operators Subject RIV: BE - Theoretical Physics Impact factor: 0.545, year: 2014

The concept of presence in group psychotherapy: an operational definition.

Science.gov (United States)

Crane-Okada, Rebecca

2012-07-01

The paper aims to operationally define the concept of presence, as developed and exhibited by the therapist leading a psychotherapy group, and illustrated with case examples. A group therapist, who addresses tangible, basic group survival needs, while integrating knowledge of psychotherapeutic processes, authentic and effective interpersonal communications, and genuine concern for individual members and the group as a whole, is best situated to enact presence in the context of group psychotherapy. Establishing presence can be achieved in a systematic way with an understanding of the meaning of being present at each step in the development of the group psychotherapeutic process. © 2011 Wiley Periodicals, Inc.

On the Galois cohomology of unipotent groups and extensions of non-perfect fields

International Nuclear Information System (INIS)

Nguyen Duy Tan; Nguyen Quoc Thang

2006-12-01

In this note we discuss, in the case of unipotent groups over non-perfect fields, an analog of Serre's conjectures for unipotent algebraic group schemes, which relates properties of Galois (or flat) cohomology of unipotent group schemes to finite extensions of non-perfect fields, and Russel's defining equations of one-dimensional unipotent groups. (author)

Renormalization Group Reduction of Non Integrable Hamiltonian Systems

International Nuclear Information System (INIS)

Tzenov, Stephan I.

2002-01-01

Based on Renormalization Group method, a reduction of non integratable multi-dimensional Hamiltonian systems has been performed. The evolution equations for the slowly varying part of the angle-averaged phase space density and for the amplitudes of the angular modes have been derived. It has been shown that these equations are precisely the Renormalization Group equations. As an application of the approach developed, the modulational diffusion in one-and-a-half degrees of freedom dynamical system has been studied in detail

47 CFR 25.220 - Non-conforming transmit/receive earth station operations.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Non-conforming transmit/receive earth station operations. 25.220 Section 25.220 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES SATELLITE COMMUNICATIONS Technical Standards § 25.220 Non-conforming transmit/receive...

Computer software design description for the Treated Effluent Disposal Facility (TEDF), Project L-045H, Operator Training Station (OTS)

International Nuclear Information System (INIS)

Carter, R.L. Jr.

1994-01-01

The Treated Effluent Disposal Facility (TEDF) Operator Training Station (OTS) is a computer-based training tool designed to aid plant operations and engineering staff in familiarizing themselves with the TEDF Central Control System (CCS)

Non-Power Reactor Operator Licensing Examiner Standards. Revision 1

International Nuclear Information System (INIS)

1995-06-01

The Non-Power Reactor Operator Licensing Examiner Standards provide policy and guidance to NRC examiners and establish the procedures and practices for examining and licensing of applicants for NRC operator licenses pursuant to Part 55 of Title 10 of the Code of Federal Regulations (10 CFR 55). They are intended to assist NRC examiners and facility licensees to understand the examination process better and to provide for equitable and consistent administration of examinations to all applicants by NRC examiners. These standards are not a substitute for the operator licensing regulations and are subject to revision or other internal operator examination licensing policy changes. As appropriate, these standards will be revised periodically to accommodate comments and reflect new information or experience

Non-Power Reactor Operator Licensing Examiner Standards. Revision 1

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-06-01

The Non-Power Reactor Operator Licensing Examiner Standards provide policy and guidance to NRC examiners and establish the procedures and practices for examining and licensing of applicants for NRC operator licenses pursuant to Part 55 of Title 10 of the Code of Federal Regulations (10 CFR 55). They are intended to assist NRC examiners and facility licensees to understand the examination process better and to provide for equitable and consistent administration of examinations to all applicants by NRC examiners. These standards are not a substitute for the operator licensing regulations and are subject to revision or other internal operator examination licensing policy changes. As appropriate, these standards will be revised periodically to accommodate comments and reflect new information or experience.

Interconversion of pure Gaussian states requiring non-Gaussian operations

Science.gov (United States)

Jabbour, Michael G.; García-Patrón, Raúl; Cerf, Nicolas J.

2015-01-01

We analyze the conditions under which local operations and classical communication enable entanglement transformations between bipartite pure Gaussian states. A set of necessary and sufficient conditions had been found [G. Giedke et al., Quant. Inf. Comput. 3, 211 (2003)] for the interconversion between such states that is restricted to Gaussian local operations and classical communication. Here, we exploit majorization theory in order to derive more general (sufficient) conditions for the interconversion between bipartite pure Gaussian states that goes beyond Gaussian local operations. While our technique is applicable to an arbitrary number of modes for each party, it allows us to exhibit surprisingly simple examples of 2 ×2 Gaussian states that necessarily require non-Gaussian local operations to be transformed into each other.

The complex relationship between lung tumor volume and survival in patients with non-small cell lung cancer treated by definitive radiotherapy: A prospective, observational prognostic factor study of the Trans-Tasman Radiation Oncology Group (TROG 99.05)

International Nuclear Information System (INIS)

Ball, David L.; Fisher, Richard J.; Burmeister, Bryan H.; Poulsen, Michael G.; Graham, Peter H.; Penniment, Michael G.; Vinod, Shalini K.; Krawitz, Hedley E.; Joseph, David J.; Wheeler, Greg C.; McClure, Bev E.

2013-01-01

Background and purpose: To investigate the hypothesis that primary tumor volume is prognostic independent of T and N stages in patients with non-small cell lung cancer (NSCLC) treated by definitive radiotherapy. Materials and methods: Multicenter prospective observational study. Patient eligibility: pathologically proven stage I–III non-small cell lung cancer planned for definitive radiotherapy (minimum 50 Gy in 20 fractions) using CT-based contouring. Volumes of the primary tumor and enlarged nodes were measured according to a standardized protocol. Survival was adjusted for the effect of T and N stage. Results: There were 509 eligible patients. Five-year survival rates for tumor volume grouped by quartiles were, for increasing tumor volume, 22%, 14%, 15% and 21%. Larger primary tumor volume was associated with shorter survival (HR = 1.060 (per doubling); 95% CI 1.01–1.12; P = 0.029). However, after adjusting for the effects of T and N stage, there was no evidence for an association (HR = 1.029, 95% CI, 0.96–1.10, P = 0.39). There was evidence, however, that larger primary tumor volume was associated with an increased risk of dying, independently of T and N stage, in the first 18 months but not beyond. Conclusions: In patients treated by non-surgical means we were unable to show that lung tumor volume, overall, provides additional prognostic information beyond the T and N stage (TNM, 6th edition). There is evidence, however, that larger primary tumor volume adversely affects outcome only within the first 18 months. Larger tumor size alone should not by itself exclude patients from curative (chemo)radiotherapy

Effects of self-monitoring of glucose on distress and self-efficacy in people with non-insulin-treated Type 2 diabetes: a randomized controlled trial.

Science.gov (United States)

Malanda, U L; Bot, S D M; Kostense, P J; Snoek, F J; Dekker, J M; Nijpels, G

2016-04-01

To investigate the effects of self-monitoring of glucose in blood or urine, on diabetes-specific distress and self-efficacy, compared with usual care in people with non-insulin-treated Type 2 diabetes mellitus. One hundred and eighty-one participants with non-insulin-treated Type 2 diabetes mellitus [diabetes duration ≥ 1 year, age 45-75 years, HbA1c ≥ 53.0 mmol/mol (7.0%), self-monitoring frequency self-monitoring (n = 60), urine self-monitoring (n = 59) or usual care (n = 62). Primary outcomes were between-group differences in diabetes-specific distress [Problem Areas in Diabetes scale (PAID)] and self-efficacy [Confidence in Diabetes Self-Care questionnaire (CIDS-2)] after 12 months. Secondary outcomes included changes in HbA1c , treatment satisfaction and depressive symptoms. There were no statistically significant between-group differences in changes in PAID and CIDS-2 after 12 months. Mean difference in PAID between blood monitoring and control was -2.2 [95% confidence interval (CI) -7.1 to 2.7], between urine monitoring and control was -0.9 (95% CI -4.4 to 2.5) and between blood monitoring and urine monitoring was -2.0 (95% CI -4.1 to 0.1). Mean difference in CIDS-2 between blood monitoring and control was 0.6 [95% CI (-2.0 to 2.1), between urine monitoring and control was 2.8 (95% CI -2.3 to 7.9)] and between blood monitoring and urine monitoring was -3.3 (95% CI -7.9 to 1.3). No statistically significant between-group differences in change in any of the secondary outcome measures were found. This study did not find statistical or clinical evidence for a long-term effect of self-monitoring of glucose in blood or urine on diabetes-specific distress and self-efficacy in people with moderately controlled non-insulin-treated Type 2 diabetes mellitus. (Current Controlled Trials ISRCTN84568563). © 2015 Diabetes UK.

Advances in non-Cartesian parallel magnetic resonance imaging using the GRAPPA operator

International Nuclear Information System (INIS)

Seiberlich, Nicole

2008-01-01

This thesis has presented several new non-Cartesian parallel imaging methods which simplify both gridding and the reconstruction of images from undersampled data. A novel approach which uses the concepts of parallel imaging to grid data sampled along a non-Cartesian trajectory called GRAPPA Operator Gridding (GROG) is described. GROG shifts any acquired k-space data point to its nearest Cartesian location, thereby converting non-Cartesian to Cartesian data. The only requirements for GROG are a multi-channel acquisition and a calibration dataset for the determination of the GROG weights. Then an extension of GRAPPA Operator Gridding, namely Self-Calibrating GRAPPA Operator Gridding (SC-GROG) is discussed. SC-GROG is a method by which non-Cartesian data can be gridded using spatial information from a multi-channel coil array without the need for an additional calibration dataset, as required in standard GROG. Although GROG can be used to grid undersampled datasets, it is important to note that this method uses parallel imaging only for gridding, and not to reconstruct artifact-free images from undersampled data. Thereafter a simple, novel method for performing modified Cartesian GRAPPA reconstructions on undersampled non-Cartesian k-space data gridded using GROG to arrive at a non-aliased image is introduced. Because the undersampled non-Cartesian data cannot be reconstructed using a single GRAPPA kernel, several Cartesian patterns are selected for the reconstruction. Finally a novel method of using GROG to mimic the bunched phase encoding acquisition (BPE) scheme is discussed. In MRI, it is generally assumed that an artifact-free image can be reconstructed only from sampled points which fulfill the Nyquist criterion. However, the BPE reconstruction is based on the Generalized Sampling Theorem of Papoulis, which states that a continuous signal can be reconstructed from sampled points as long as the points are on average sampled at the Nyquist frequency. A novel

Non-Operational Property Evaluation for the Hanford Site River Corridor - 12409

Energy Technology Data Exchange (ETDEWEB)

Lowe, John [CH2M HILL, Richland, Washington 99354 (United States); Aly, Alaa [CH2M HILL Plateau Remediation Company and INTERA Incorporated, Richland, Washington 99354 (United States)

2012-07-01

The Hanford Site River Corridor consists of the former reactor areas of the 100 Areas and the former industrial (fuel processing) area in the 300 Area. Most of the waste sites are located close to the decommissioned reactors or former industrial facilities along the Columbia River. Most of the surface area of the River Corridor consists of land with little or no subsurface infrastructure or indication of past or present releases of hazardous constituents, and is referred to as non-operational property or non-operational area. Multiple lines of evidence have been developed to assess identified fate and transport mechanisms and to evaluate the potential magnitude and significance of waste site-related contaminants in the non-operational area. Predictive modeling was used for determining the likelihood of locating waste sites and evaluating the distribution of radionuclides in soil based on available soil concentration data and aerial radiological surveys. The results of this evaluation indicated: 1) With the exception of stack emissions, transport pathways associated with waste site contaminants are unlikely to result in dispersion of contaminants in soil away from operational areas, 2) Stack emissions that may have been associated with Hanford Site operations generally emitted short-lived and/or gaseous radionuclides, and (3) the likelihood of detecting elevated radionuclide concentrations or other waste sites in non-operational area soils is very small. The overall conclusions from the NPE evaluation of the River Corridor are: - With the exception of stack emissions to the air, transport pathways associated with waste site contaminants are unlikely to result in dispersion of contaminants in soil away from operational areas. While pathways such as windblown dust, overland transport and biointrusion have the potential for dispersing waste site contaminants, the resulting transport is unlikely to result in substantial contamination in non-operational areas. - Stack

Teleportation protocol with non-ideal conditional local operations

Energy Technology Data Exchange (ETDEWEB)

Di Franco, C., E-mail: cdifranco@caesar.ucc.i [Department of Physics, University College Cork, Cork (Ireland); Ballester, D. [School of Mathematics and Physics, Queen' s University, Belfast BT7 1NN (United Kingdom)

2010-07-12

We analyze teleportation protocol when some of receiver's conditional operations are more reliable than others and a non-maximally entangled channel is shared by the two parts. We show that the average fidelity of teleportation can be maximized by choosing properly the basis in which the sender performs her two-qubit measurement.

Non-perturbative renormalisation of left-left four-fermion operators with Neuberger fermions

International Nuclear Information System (INIS)

Dimopoulos, P.; Giusti, L.; Hernandez, P.; Palombi, F.; Pena, C.; Vladikas, A.; Wennekers, J.; Wittig, H.

2006-01-01

We outline a general strategy for the non-perturbative renormalisation of composite operators in discretisations based on Neuberger fermions, via a matching to results obtained with Wilson-type fermions. As an application, we consider the renormalisation of the four-quark operators entering the ΔS=1 and ΔS=2 effective Hamiltonians. Our results are an essential ingredient for the determination of the low-energy constants governing non-leptonic kaon decays

Quantum groups: Geometry and applications

International Nuclear Information System (INIS)

Chu, C.S.

1996-01-01

The main theme of this thesis is a study of the geometry of quantum groups and quantum spaces, with the hope that they will be useful for the construction of quantum field theory with quantum group symmetry. The main tool used is the Faddeev-Reshetikhin-Takhtajan description of quantum groups. A few content-rich examples of quantum complex spaces with quantum group symmetry are treated in details. In chapter 1, the author reviews some of the basic concepts and notions for Hopf algebras and other background materials. In chapter 2, he studies the vector fields of quantum groups. A compact realization of these vector fields as pseudodifferential operators acting on the linear quantum spaces is given. In chapter 3, he describes the quantum sphere as a complex quantum manifold by means of a quantum stereographic projection. A covariant calculus is introduced. An interesting property of this calculus is the existence of a one-form realization of the exterior differential operator. The concept of a braided comodule is introduced and a braided algebra of quantum spheres is constructed. In chapter 4, the author considers the more general higher dimensional quantum complex projective spaces and the quantum Grassman manifolds. Differential calculus, integration and braiding can be introduced as in the one dimensional case. Finally, in chapter 5, he studies the framework of quantum principal bundle and construct the q-deformed Dirac monopole as a quantum principal bundle with a quantum sphere as the base and a U(1) with non-commutative calculus as the fiber. The first Chern class can be introduced and integrated to give the monopole charge

Group Insight Versus Group Desensitization in Treating Speech Anxiety

Science.gov (United States)

Meichenbaum, Donald H.; And Others

1971-01-01

Results of this study indicated that the insight group was as effective as the desensitization group in significantly reducing speech anxiety over control group levels as assessed by behavioral, cognitive, and self-report measures given immediately after posttreatment and later at a three-month follow-up. (Author)

Non metrizable topologies on Z with countable dual group.

Directory of Open Access Journals (Sweden)

Daniel de la Barrera Mayoral

2017-04-01

Full Text Available In this paper we give two families of non-metrizable topologies on the group of the integers having a countable dual group which is isomorphic to a infinite torsion subgroup of the unit circle in the complex plane. Both families are related to D-sequences, which are sequences of natural numbers such that each term divides the following. The first family consists of locally quasi-convex group topologies. The second consists of complete topologies which are not locally quasi-convex. In order to study the dual groups for both families we need to make numerical considerations of independent interest.

The peri-operative management of anti-platelet therapy in elective, non-cardiac surgery.

Science.gov (United States)

Alcock, Richard F; Naoum, Chris; Aliprandi-Costa, Bernadette; Hillis, Graham S; Brieger, David B

2013-07-31

Cardiovascular complications are important causes of morbidity and mortality in patients undergoing elective non-cardiac surgery, with adverse cardiac outcomes estimated to occur in approximately 4% of all patients. Anti-platelet therapy withdrawal may precede up to 10% of acute cardiovascular syndromes, with withdrawal in the peri-operative setting incompletely appraised. The aims of our study were to determine the proportion of patients undergoing elective non-cardiac surgery currently prescribed anti-platelet therapy, and identify current practice in peri-operative management. In addition, the relationship between management of anti-platelet therapy and peri-operative cardiac risk was assessed. We evaluated consecutive patients attending elective non-cardiac surgery at a major tertiary referral centre. Clinical and biochemical data were collected and analysed on patients currently prescribed anti-platelet therapy. Peri-operative management of anti-platelet therapy was compared with estimated peri-operative cardiac risk. Included were 2950 consecutive patients, with 516 (17%) prescribed anti-platelet therapy, primarily for ischaemic heart disease. Two hundred and eighty nine (56%) patients had all anti-platelet therapy ceased in the peri-operative period, including 49% of patients with ischaemic heart disease and 46% of patients with previous coronary stenting. Peri-operative cardiac risk score did not influence anti-platelet therapy management. Approximately 17% of patients undergoing elective non-cardiac surgery are prescribed anti-platelet therapy, the predominant indication being for ischaemic heart disease. Almost half of all patients with previous coronary stenting had no anti-platelet therapy during the peri-operative period. The decision to cease anti-platelet therapy, which occurred commonly, did not appear to be guided by peri-operative cardiac risk stratification. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

On a correspondence between regular and non-regular operator monotone functions

DEFF Research Database (Denmark)

Gibilisco, P.; Hansen, Frank; Isola, T.

2009-01-01

We prove the existence of a bijection between the regular and the non-regular operator monotone functions satisfying a certain functional equation. As an application we give a new proof of the operator monotonicity of certain functions related to the Wigner-Yanase-Dyson skew information....

A group property for the coherent state representation of fermionic squeezing operators

Science.gov (United States)

Fan, Hong-yi; Li, Chao

2004-06-01

For the two-mode fermionic squeezing operators we find that their coherent state projection operator representation make up a loyal representation, which is homomorphic to an SO(4) group, though the fermionic coherent states are not mutual orthogonal. Thus the result of successively operating with many fermionic squeezing operators on a state can be equivalent to a single operation. The fermionic squeezing operators are mappings of orthogonal transformations in Grassmann number pseudo-classical space in the fermionic coherent state representation.

A group property for the coherent state representation of fermionic squeezing operators

International Nuclear Information System (INIS)

Fan Hongyi; Li Chao

2004-01-01

For the two-mode fermionic squeezing operators we find that their coherent state projection operator representation make up a loyal representation, which is homomorphic to an SO(4) group, though the fermionic coherent states are not mutual orthogonal. Thus the result of successively operating with many fermionic squeezing operators on a state can be equivalent to a single operation. The fermionic squeezing operators are mappings of orthogonal transformations in Grassmann number pseudo-classical space in the fermionic coherent state representation

Traumatic events, other operational stressors and physical and mental health reported by Australian Defence Force personnel following peacekeeping and war-like deployments

Directory of Open Access Journals (Sweden)

Waller Michael

2012-07-01

Full Text Available Abstract Background The association between stressful events on warlike deployments and subsequent mental health problems has been established. Less is known about the effects of stressful events on peacekeeping deployments. Methods Two cross sectional studies of the Australian Defence Force were used to contrast the prevalence of exposures reported by a group deployed on a peacekeeping operation (Bougainville, n = 1704 and those reported by a group deployed on operations which included warlike and non-warlike exposures (East Timor, n = 1333. A principal components analysis was used to identify groupings of non-traumatic exposures on deployment. Multiple regression models were used to assess the association between self-reported objective and subjective exposures, stressors on deployment and subsequent physical and mental health outcomes. Results The principal components analysis produced four groups of non-traumatic stressors which were consistent between the peacekeeping and more warlike deployments. These were labelled ‘separation’, ‘different culture’, ‘other people’ and ‘work frustration’. Higher levels of traumatic and non-traumatic exposures were reported by veterans of East Timor compared to Bougainville. Higher levels of subjective traumatic exposures were associated with increased rates of PTSD in East Timor veterans and more physical and psychological health symptoms in both deployed groups. In Bougainville and East Timor veterans some non-traumatic deployment stressors were also associated with worse health outcomes. Conclusion Strategies to best prepare, identify and treat those exposed to traumatic events and other stressors on deployment should be considered for Defence personnel deployed on both warlike and peacekeeping operations.

Comparison of the Efficacy and Safety of Icotinib with Standard Second-line 
Chemotherapy in Previously Treated Advanced Non-small Cell Lung Cancer

Directory of Open Access Journals (Sweden)

Shuyang YAO

2015-06-01

Full Text Available Background and objective This study compared the efficacy and safety of icotinib with standard second-line chemotherapy (single-agent docetaxel or pemetrexed in previously treated advanced non-small cell lung cancer (NSCLC. Methods Thirty-two consecutive patients treated with icotinib and 33 consecutive patients treated with standard second-line chemotherapy in Xuanwu Hospital from January 2012 to July 2013 were enrolled in our retrospective research. The Response Evaluation Criteria in Solid Tumors were used to evaluate the tumor responses, and the progression-free survival (PFS was evaluated by Kaplan-Meier method. Results Icotinib was comparable with standard second-line chemotherapy for advanced NSCLC in terms of overall response rate (ORR (28.1% vs 18.2%, P=0.341, disease control rate (DFS(43.8% vs 45.5%, P=0.890, and PFS (4.3 months vs 3.8 months, P=0.506. In the icotinib group, the ORR of epidermal growth factor receptor (EGFR mutant was significantly higher than that of EGFR unknown or wild type (P=0.017. In multivariate analysis, age, gender, histology, and the optimum first-line treatment response were dependent prognostic factors based on the PFS of the icotinib group. The incidence of adverse events was significantly fewer in the icotinib group than in the chemotherapy group (P=0.001. Conclusion Compared with the standard second-line chemotherapy, icotinib is active in the treatment of advanced NSCLC patients, especially with EGFR unknown in the second line, with an acceptable adverse event profile.

The chirality operators for Heisenberg spin systems

International Nuclear Information System (INIS)

Subrahmanyam, V.

1994-01-01

The ground state of closed Heisenberg spin chains with an odd number of sites has a chiral degeneracy, in addition to a two-fold Kramers degeneracy. A non-zero chirality implies that the spins are not coplanar, and is a measure of handedness. The chirality operator, which can be treated as a spin-1/2 operator, is explicitly constructed in terms of the spin operators, and is given as commutator of permutation operators. (author). 3 refs

Harmonic analysis and global solvability of a differential operator invariant on motion groups and semi-simple Lie groups

International Nuclear Information System (INIS)

El-Hussein, K.

1991-08-01

Let V be a real finite dimensional vector space and let K be a connected compact Lie group, which acts on V by means of a continuous linear representation ρ. Let G=V x p K be the motion group which is the semi-direct product of V by K and let P be an invariant differential operator on G. In this paper we give a necessary and sufficient condition for the global solvability of P on G. Now let G be a connected semi-simple Lie group with finite centre and let P be an invariant differential operator on G. We give also a necessary and sufficient condition for the global solvability of P on G. (author). 8 refs

Special issue on quantum physics with non-Hermitian operators Special issue on quantum physics with non-Hermitian operators

Science.gov (United States)

Bender, Carl M.; Fring, Andreas; Guenther, Uwe; Jones, Hugh F.

2012-01-01

This is a call for contributions to a special issue of Journal of Physics A: Mathematical and Theoretical dedicated to quantum physics with non-Hermitian operators. The main motivation behind this special issue is to gather together recent results, developments and open problems in this rapidly evolving field of research in a single comprehensive volume. We expect that such a special issue will become a valuable reference for the broad scientific community working in mathematical and theoretical physics. The issue will be open to all contributions containing new results on non-Hermitian theories which are explicitly PT-symmetric and/or pseudo-Hermitian or quasi-Hermitian. The main novelties in the past years in this area have been many experimental observations, realizations, and applications of PT symmetric Hamiltonians in optics and microwave cavities. We especially invite contributions on the theoretical interpretations of these recent PT-symmetric experiments and on theoretical proposals for new experiments. Editorial policy The Guest Editors for this issue are Carl Bender, Andreas Fring, Uwe Guenther and Hugh Jones. The areas and topics for this issue include, but are not limited to: spectral problems novel properties of complex optical potentials PT-symmetry related threshold lasers and spectral singularities construction of metric operators scattering theory supersymmetric theories Lie algebraic and Krein-space methods random matrix models classical and semi-classical models exceptional points in model systems operator theoretic approaches microwave cavities aspects of integrability and exact solvability field theories with indefinite metric All contributions will be refereed and processed according to the usual procedure of the journal. Papers should report original and significant research that has not already been published. Guidelines for preparation of contributions The deadline for contributed papers will be 31 March 2012. This deadline will allow the

Significance of ABO-Rh blood groups in response and prognosis in breast cancer patients treated with radiotherapy and chemotherapy.

Science.gov (United States)

Cihan, Yasemin Benderli

2014-01-01

To evaluate whether ABO-Rh blood groups have significance in the treatment response and prognosis in patients with non-metastatic breast cancer. We retrospectively evaluated files of 335 patients with breast cancer who were treated between 2005 and 2010. Demographic data, clinic- pathological findings, treatments employed, treatment response, and overall and disease-free survivals were reviewed. Relationships between clinic-pathological findings and blood groups were evaluated. 329 women and 6 men were included to the study. Mean age at diagnosis was 55.2 years (range: 26-86). Of the cases, 95% received chemotherapy while 70% were given radiotherapy and 60.9% adjuvant hormone therapy after surgery. Some 63.0% were A blood group, 17.6% O, 14.3% B and 5.1% AB. In addition, 82.0% of the cases were Rh-positive. Mean follow-up was 24.5 months. Median overall and progression-free survival times were 83.9 and 79.5 months, respectively. Overall and disease-free survival times were found to be higher in patients with A and O blood groups (pgroup (p=0.226). In univariate and multivariate analyses, ABO blood groups were identified as factors that had significant effects on overall and disease-survival times (p=0.011 and p=0.002). It was seen that overall and disease-free survival times were higher in breast cancer patients with A and O blood groups when compared to those with other blood groups. It was seen that A and O blood groups had good prognostic value in patients with breast cancer.

Renormalization group, operator product expansion and anomalous scaling in models of turbulent advection

International Nuclear Information System (INIS)

Antonov, N V

2006-01-01

Recent progress on the anomalous scaling in models of turbulent heat and mass transport is reviewed with the emphasis on the approach based on the field-theoretic renormalization group (RG) and operator product expansion (OPE). In that approach, the anomalous scaling is established as a consequence of the existence in the corresponding field-theoretic models of an infinite number of 'dangerous' composite fields (operators) with negative critical dimensions, which are identified with the anomalous exponents. This allows one to calculate the exponents in a systematic perturbation expansion, similar to the ε expansion in the theory of critical phenomena. The RG and OPE approach is presented in a self-contained way for the example of a passive scalar field (temperature, concentration of an impurity, etc) advected by a self-similar Gaussian velocity ensemble with vanishing correlation time, the so-called Kraichnan's rapid-change model, where the anomalous exponents are known up to order O(ε 3 ). Effects of anisotropy, compressibility and the correlation time of the velocity field are discussed. Passive advection by non-Gaussian velocity field governed by the stochastic Navier-Stokes equation and passively advected vector (e.g. magnetic) fields are considered

The efficacy of a brief group CBT program in treating patients diagnosed with bulimia nervosa: a brief report

DEFF Research Database (Denmark)

Jones, Allan; Clausen, Loa

2013-01-01

OBJECTIVE: The aim of the study was to evaluate the efficacy of a brief group cognitive behavior therapy (CBT) program in treating a large cohort of patients diagnosed with bulimia nervosa. METHOD: Treatment outcome defined as reductions in bulimia related behavioral symptoms and bulimia related...... distress was examined in 205 consecutive new patients enrolled in an eight-session group CBT program. RESULTS: Significant reductions in eating disorder pathology were found on all measures of bulimia related behavioral symptoms, as well as on all measures of bulimia related distress. DISCUSSION......: There is strong evidence for the efficacy of brief group CBT in treating patients with bulimia nervosa....

Effect of non-normality on test statistics for one-way independent groups designs.

Science.gov (United States)

Cribbie, Robert A; Fiksenbaum, Lisa; Keselman, H J; Wilcox, Rand R

2012-02-01

The data obtained from one-way independent groups designs is typically non-normal in form and rarely equally variable across treatment populations (i.e., population variances are heterogeneous). Consequently, the classical test statistic that is used to assess statistical significance (i.e., the analysis of variance F test) typically provides invalid results (e.g., too many Type I errors, reduced power). For this reason, there has been considerable interest in finding a test statistic that is appropriate under conditions of non-normality and variance heterogeneity. Previously recommended procedures for analysing such data include the James test, the Welch test applied either to the usual least squares estimators of central tendency and variability, or the Welch test with robust estimators (i.e., trimmed means and Winsorized variances). A new statistic proposed by Krishnamoorthy, Lu, and Mathew, intended to deal with heterogeneous variances, though not non-normality, uses a parametric bootstrap procedure. In their investigation of the parametric bootstrap test, the authors examined its operating characteristics under limited conditions and did not compare it to the Welch test based on robust estimators. Thus, we investigated how the parametric bootstrap procedure and a modified parametric bootstrap procedure based on trimmed means perform relative to previously recommended procedures when data are non-normal and heterogeneous. The results indicated that the tests based on trimmed means offer the best Type I error control and power when variances are unequal and at least some of the distribution shapes are non-normal. © 2011 The British Psychological Society.

Results of concomitant cisplatin and radiotherapy in non-operable non small-cell lung cancer

International Nuclear Information System (INIS)

Antoine, E.; Mazeron, J.J.

1993-01-01

The Radiotherapy and Lung Cancer Cooperative Groups of the EORTC performed a randomized study in patients with non-metastatic inoperable non small-cell lung cancer to compare the results of radiotherapy alone (radiation was administered for two wk at a dose of 3 Gy given 10 times followed by a three-wk rest period and then radiotherapy for two more wk at a dose of 2.5 Gy given 10 times) with radiotherapy on the same schedule combined with cisplatin given either on the first day of each treatment week at a dose of 30 mg/m 2 , or daily before radiotherapy at a dose of 6 mg/m 2 . Preliminary results showed a significantly improved three-yr survival rate in the radiotherapy-daily cisplatin group as compared with the radiotherapy group (16% versus 2%; P = 0.009) and without major increase in toxicity. This survival benefit was due to improved control of local disease; survival without local recurrence was 31% at two yr in the radiotherapy-daily cisplatin group as compared with 19% in the radiotherapy (P = 0.003)

78 FR 61387 - Supermedia LLC, Publishing Operations Divison, Account Management Group, a Subsidiary of Dex...

Science.gov (United States)

2013-10-03

... LLC, Publishing Operations Divison, Account Management Group, a Subsidiary of Dex Media Inc..., Publishing Operations Divison, Listing Management Group, a Subsidiary of Dex Media Inc., Including On-Site... to workers and former workers of SuperMedia LLC, Publishing Operation Division, Account Management...

Pressure of non-professional use of pesticides on operators, aquatic organisms and bees in Belgium.

Science.gov (United States)

Fevery, Davina; Houbraken, Michael; Spanoghe, Pieter

2016-04-15

Various studies focus on professional pesticide use, whereas pressure of non-professional use on human and the environment is often neglected. In this study, an attempt was made to estimate the pressure of non-professional use of pesticides on operators, aquatic organisms and bees in Belgium based on sales figures and by using three exposure models. A classification in non-professional use was made based on type of pesticide, application method and on intensity of non-professional use. Pressure of non-professional use on operators is highest for intensive operators, caused by the use of insecticides in an aerosol spray can. Pressure of non-professional pesticides on aquatic life is mainly generated by the use of herbicides. The aerosol spray induces the highest pressure whereas the trigger application hardly affects operator and environmental exposure. The ordinary non-professional user generates most pressure on aquatic organisms. Pressure of non-professional pesticides on bees is mainly caused by the use of insecticides, especially the active substance imidacloprid in combination with the aerosol spray can application method applied by an intensive operator. In general, both total usage (kg) and pressure of pesticides decreased for the period 2005 to 2012 due to efforts made by the government and industry. The results of this study suggest to pay special attention to aerosol spray applications and the non-professional use of insecticides. Copyright © 2016 Elsevier B.V. All rights reserved.

Detecting non-binomial sex allocation when developmental mortality operates.

Science.gov (United States)

Wilkinson, Richard D; Kapranas, Apostolos; Hardy, Ian C W

2016-11-07

Optimal sex allocation theory is one of the most intricately developed areas of evolutionary ecology. Under a range of conditions, particularly under population sub-division, selection favours sex being allocated to offspring non-randomly, generating non-binomial variances of offspring group sex ratios. Detecting non-binomial sex allocation is complicated by stochastic developmental mortality, as offspring sex can often only be identified on maturity with the sex of non-maturing offspring remaining unknown. We show that current approaches for detecting non-binomiality have limited ability to detect non-binomial sex allocation when developmental mortality has occurred. We present a new procedure using an explicit model of sex allocation and mortality and develop a Bayesian model selection approach (available as an R package). We use the double and multiplicative binomial distributions to model over- and under-dispersed sex allocation and show how to calculate Bayes factors for comparing these alternative models to the null hypothesis of binomial sex allocation. The ability to detect non-binomial sex allocation is greatly increased, particularly in cases where mortality is common. The use of Bayesian methods allows for the quantification of the evidence in favour of each hypothesis, and our modelling approach provides an improved descriptive capability over existing approaches. We use a simulation study to demonstrate substantial improvements in power for detecting non-binomial sex allocation in situations where current methods fail, and we illustrate the approach in real scenarios using empirically obtained datasets on the sexual composition of groups of gregarious parasitoid wasps. Copyright © 2016 Elsevier Ltd. All rights reserved.

[Comparative study on Chinese medical syndrome typing and treatment combined different surgical methods for treating clomiphene-resistant polycystic ovary syndrome].

Science.gov (United States)

Zeng, Lei; Zeng, Cheng; Tao, Li-Li

2012-11-01

To observe the therapeutic efficacy of Chinese medical syndrome typing and treatment combined cold needle puncture drainage operation or unipolar electrocoagulation drilling technique under laparoscope for treating clomiphene-resistant polycystic ovary syndrome (PCOS). Forty infertility patients with clomiphene-resistant PCOS were assigned to two groups using stratified random sampling method according to age, infertility time, and body mass index, 20 in each group. Patients in Group A were treated with Chinese medical syndrome typing and treatment combined cold needle puncture drainage operation, while those in Group B were treated with Chinese medical syndrome typing and treatment combined unipolar electrocoagulation drilling technique. After operation Chinese herbal treatment was administered to all patients according to syndrome typing. The serum levels of luteinizing hormone (LH), follicle stimulating hormone (FSH), androgen (T), estradiol (E2), and prolactin (PRL) were determined before and after operation. The ovulation was monitored. The pregnancy rate and the pregnancy outcomes were recorded after operation. There was no statistical difference in the 3-month spontaneous ovulation rate or the 1-year pregnancy rate (P > 0.05). The levels of LH, T, and PRL were significantly lower after operation than before operation in the two groups (P typing and treatment combined cold needle puncture drainage operation or unipolar electrocoagulation drilling technique could effectively promote the ovulation. The two methods showed similar therapeutic effects.

Advances in non-Cartesian parallel magnetic resonance imaging using the GRAPPA operator

Energy Technology Data Exchange (ETDEWEB)

Seiberlich, Nicole

2008-07-21

This thesis has presented several new non-Cartesian parallel imaging methods which simplify both gridding and the reconstruction of images from undersampled data. A novel approach which uses the concepts of parallel imaging to grid data sampled along a non-Cartesian trajectory called GRAPPA Operator Gridding (GROG) is described. GROG shifts any acquired k-space data point to its nearest Cartesian location, thereby converting non-Cartesian to Cartesian data. The only requirements for GROG are a multi-channel acquisition and a calibration dataset for the determination of the GROG weights. Then an extension of GRAPPA Operator Gridding, namely Self-Calibrating GRAPPA Operator Gridding (SC-GROG) is discussed. SC-GROG is a method by which non-Cartesian data can be gridded using spatial information from a multi-channel coil array without the need for an additional calibration dataset, as required in standard GROG. Although GROG can be used to grid undersampled datasets, it is important to note that this method uses parallel imaging only for gridding, and not to reconstruct artifact-free images from undersampled data. Thereafter a simple, novel method for performing modified Cartesian GRAPPA reconstructions on undersampled non-Cartesian k-space data gridded using GROG to arrive at a non-aliased image is introduced. Because the undersampled non-Cartesian data cannot be reconstructed using a single GRAPPA kernel, several Cartesian patterns are selected for the reconstruction. Finally a novel method of using GROG to mimic the bunched phase encoding acquisition (BPE) scheme is discussed. In MRI, it is generally assumed that an artifact-free image can be reconstructed only from sampled points which fulfill the Nyquist criterion. However, the BPE reconstruction is based on the Generalized Sampling Theorem of Papoulis, which states that a continuous signal can be reconstructed from sampled points as long as the points are on average sampled at the Nyquist frequency. A novel

Non-financial reporting, CSR frameworks and groups of undertakings

DEFF Research Database (Denmark)

Szabó, Dániel Gergely; Sørensen, Karsten Engsig

2017-01-01

The recently adopted Directive on non-financial reporting (Directive 2014/95/EU) and several CSR frameworks are based on the assumption that groups of undertakings adopt, report and implement one group policy. This is a very important but also rather unique approach to groups. This article first...... shows how the Directive as well as a few CSR frameworks intend to be implemented in groups and next it discusses potential barriers to do so. Even though company law does not always facilitate the adoption, communication and implementation of a group CSR policy, it may not in practice be a problem to do...... so. However, it is shown that doing so may have unforeseen consequences for the parent undertaking. To avoid them, it is recommended to make adjustments to the implementation of the group policy....

Non-commutative cryptography and complexity of group-theoretic problems

CERN Document Server

Myasnikov, Alexei; Ushakov, Alexander

2011-01-01

This book is about relations between three different areas of mathematics and theoretical computer science: combinatorial group theory, cryptography, and complexity theory. It explores how non-commutative (infinite) groups, which are typically studied in combinatorial group theory, can be used in public-key cryptography. It also shows that there is remarkable feedback from cryptography to combinatorial group theory because some of the problems motivated by cryptography appear to be new to group theory, and they open many interesting research avenues within group theory. In particular, a lot of emphasis in the book is put on studying search problems, as compared to decision problems traditionally studied in combinatorial group theory. Then, complexity theory, notably generic-case complexity of algorithms, is employed for cryptanalysis of various cryptographic protocols based on infinite groups, and the ideas and machinery from the theory of generic-case complexity are used to study asymptotically dominant prop...

Feasibility and yield of screening for non-communicable diseases among treated tuberculosis patients in Peru.

Science.gov (United States)

Byrne, A L; Marais, B J; Mitnick, C D; Garden, F L; Lecca, L; Contreras, C; Yauri, Y; Garcia, F; Marks, G B

2018-01-01

The increasing prevalence of non-communicable diseases (NCDs) poses a major challenge to low- and middle-income countries. Patients' engagement with health services for anti-tuberculosis treatment provides an opportunity for screening for NCDs and for linkage to care. We explored the feasibility and yield of screening for NCDs in patients treated for tuberculosis (TB) in Lima, Peru, as part of a study focused on chronic respiratory sequelae. A representative sample of community controls was recruited from the same geographical area. Screening entailed taking a medical history and performing ambulatory blood pressure measurement and urinalysis. A total of 177 participants with previous TB (33 with multidrug-resistant TB) and 161 community controls were evaluated. There was an almost four-fold increased prevalence of self-reported diabetes mellitus (DM) in the TB group (adjusted prevalence ratio 3.66, 95%CI 1.68-8.01). Among those without self-reported DM, 3.3% had glycosuria, with a number needed to screen (NNS) of 31. The NNS to find one (new) case of hypertension or proteinuria in the TB group was respectively 24 and 5. Patient-centred care that includes pragmatic NCD screening is feasible in TB patients, and the treatment period provides a good opportunity to link patients to ongoing care.

Treated Effluent Disposal Facility

Data.gov (United States)

Federal Laboratory Consortium — Treated non-hazardous and non-radioactive liquid wastes are collected and then disposed of through the systems at the Treated Effluent Disposal Facility (TEDF). More...

Cognitive behavioral group therapy versus psychoeducational intervention in Parkinson's disease.

Science.gov (United States)

Berardelli, Isabella; Bloise, Maria Carmela; Bologna, Matteo; Conte, Antonella; Pompili, Maurizio; Lamis, Dorian A; Pasquini, Massimo; Fabbrini, Giovanni

2018-01-01

The aim of the current study was to evaluate whether cognitive behavioral group therapy has a positive impact on psychiatric, and motor and non-motor symptoms in Parkinson's disease (PD). We assigned 20 PD patients with a diagnosis of psychiatric disorder to either a 12-week cognitive behavioral therapy (CBT) group or a psychoeducational protocol. For the neurological examination, we administered the Unified Parkinson's Disease Rating Scale and the non-motor symptoms scale. The severity of psychiatric symptoms was assessed by means of the Hamilton Depression Rating Scale, the Hamilton Anxiety Rating Scale, the Brief Psychiatric Rating Scale, and the Clinical Global Impressions. Cognitive behavioral group therapy was effective in treating depression and anxiety symptoms as well as reducing the severity of non-motor symptoms in PD patients; whereas, no changes were observed in PD patients treated with the psychoeducational protocol. CBT offered in a group format should be considered in addition to standard drug therapy in PD patients.

46 CFR 520.11 - Non-vessel-operating common carriers.

Science.gov (United States)

2010-10-01

... CARRIER AUTOMATED TARIFFS § 520.11 Non-vessel-operating common carriers. (a) Financial responsibility. An... its tariff publication: (1) That it has furnished the Commission proof of its financial responsibility..., insurance policy, or guaranty; (5) The number of the bond, insurance policy or guaranty; and (6) Where...

Factors predicting the outcome of non-operative management of ...

African Journals Online (AJOL)

A.M. Maarouf

Predictors of non-operative management failure of high-grade blunt renal trauma. 45 and computed .... perform univariate and multivariate analyses of the risk factors. The .... possible. At our institutions, renal trauma management decisions were based on the ... gency nephrectomy and thus limits the possibility of preserving.

Flurbiprofen : A non-selective cyclooxygenase (COX) inhibitor for treatment of non-infectious, non-necrotising anterior scleritis

Science.gov (United States)

Agrawal, Rupesh; Lee, Cecilia; Gonzalez-Lopez, Julio J.; Khan, Sharmina; Rodrigues, Valeria; Pavesio, Carlos

2016-01-01

Objective To analyse the safety and efficacy of a non-selective cyclo-oxygenase (COX) inhibitor in the management of non-infectious, non-necrotising anterior scleritis. Methods Retrospective chart review of 126 patients with non-necrotising anterior scleritis treated with oral flurbiprofen (Froben®(Abbott Healthcare)) with ( group B, n=61) or without topical steroids (group A, n=65) was performed and time to remission was plotted. Results The observed incidence rate was 1.07 (95% CI: 0.57–1.99) per 1000 person-years with failure rate of 0.68 (95% CI: 0.22–2.12) per 1000 person-years in group A and 1.41 (95% CI: 0.67–2.96) per 1000 person-years in group B. The failure rate was 3.97(1.89–9.34) per 1000 person-years with hazard ratio of 10.01 ( 95% CI: 2.52–39.65; p<0.001) for patients with associated systemic disease. Conclusion To our best knowledge, this is the first and largest case series on the safety and efficacy of a non-selective COX inhibitor in the management of anterior scleritis. PMID:26308394

Induced representations of the affine group and intertwining operators: I. Analytical approach

International Nuclear Information System (INIS)

Elmabrok, Abdelhamid S; Hutník, Ondrej

2012-01-01

We analyze the construction and origin of unitary operators describing the structure of the space of continuous wavelet transforms inside the space L 2 (G,dν L ) of all square-integrable functions on the affine group G with respect to the left-invariant Haar measure from the viewpoint of induced representations of G. We show that these operators are, in fact, intertwining operators among pairs of induced representations of the affine group G. A characterization of the space of wavelet transforms using the Cauchy–Riemann-type equations is given. This article is part of a special issue of Journal of Physics A: Mathematical and Theoretical devoted to ‘Coherent states: mathematical and physical aspects’. (paper)

The temporal course of mucoperiosteal flap revascularization at guided bone regeneration treated implant sites: a pilot study

NARCIS (Netherlands)

Milstein, D.M.J.; Mathura, K.R.; Lindeboom, J.A.H.; Ramsoekh, D.; Lindeboom, R.; Ince, C.

2009-01-01

Aims: To investigate post-operative capillary density regeneration in healing mucoperiosteal flaps at guided bone regeneration-treated implant sites. Material and Methods: A non-invasive post-operative investigation was performed in 10 patients using orthogonal polarization spectral (OPS) imaging

Metrics on the Phase Space and Non-Selfadjoint Pseudo-Differential Operators

CERN Document Server

Lerner, Nicolas

2010-01-01

This book is devoted to the study of pseudo-differential operators, with special emphasis on non-selfadjoint operators, a priori estimates and localization in the phase space. We expose the most recent developments of the theory with its applications to local solvability and semi-classical estimates for nonselfadjoint operators. The first chapter is introductory and gives a presentation of classical classes of pseudo-differential operators. The second chapter is dealing with the general notion of metrics on the phase space. We expose some elements of the so-called Wick calculus and introduce g

Acute toxicity in prostate cancer patients treated with and without image-guided radiotherapy

Directory of Open Access Journals (Sweden)

Williams Scott

2011-10-01

Full Text Available Abstract Background Image-guided radiotherapy (IGRT increases the accuracy of treatment delivery through daily target localisation. We report on toxicity symptoms experienced during radiotherapy treatment, with and without IGRT in prostate cancer patients treated radically. Methods Between 2006 and 2009, acute toxicity data for ten symptoms were collected prospectively onto standardized assessment forms. Toxicity was scored during radiotherapy, according to the Common Terminology Criteria Adverse Events V3.0, for 275 prostate cancer patients before and after the implementation of a fiducial marker IGRT program and dose escalation from 74Gy in 37 fractions, to 78Gy in 39 fractions. Margins and planning constraints were maintained the same during the study period. The symptoms scored were urinary frequency, cystitis, bladder spasm, urinary incontinence, urinary retention, diarrhoea, haemorrhoids, proctitis, anal skin discomfort and fatigue. Analysis was conducted for the maximum grade of toxicity and the median number of days from the onset of that toxicity to the end of treatment. Results In the IGRT group, 14228 toxicity scores were analysed from 249 patients. In the non-IGRT group, 1893 toxicity scores were analysed from 26 patients. Urinary frequency ≥G3 affected 23% and 7% in the non-IGRT and IGRT group respectively (p = 0.0188. Diarrhoea ≥G2 affected 15% and 3% of patients in the non-IGRT and IGRT groups (p = 0.0174. Fatigue ≥G2 affected 23% and 8% of patients in the non-IGRT and IGRT groups (p = 0.0271. The median number of days with a toxicity was higher for ≥G2 (p = 0.0179 and ≥G3 frequency (p = 0.0027, ≥G2 diarrhoea (p = 0.0033 and ≥G2 fatigue (p = 0.0088 in the non-IGRT group compared to the IGRT group. Other toxicities were not of significant statistical difference. Conclusions In this study, prostate cancer patients treated radically with IGRT had less severe urinary frequency, diarrhoea and fatigue during treatment

Presentation of the GIE INTRA Group's operational means

International Nuclear Information System (INIS)

Cochard, A.

2010-01-01

Located on the Chinon nuclear power plant site, the Intra Group is an economic interest grouping which has been created by the three French nuclear operators (EDF, CEA, and COGEMA now AREVA) after the Chernobyl accident. Its missions are to possess permanently available means of intervention in case of severe accident or radiological situation, to be able to intervene at any time on the French territory, to develop a European network of expertise, and to build up an ability centre for robotic intervention in hostile environment. This document briefly presents its different available means: remotely controlled equipment (inside and outside equipment, public works equipment), and radiological characterization equipment. Other aspects are briefly evoked: organization, information transmission, exercises and interventions, international relationships, future trends

Critical review on non-operative management of adolescent idiopathic scoliosis.

Science.gov (United States)

Wong, M S; Liu, W C

2003-12-01

There are a number of different non-operative interventions which aim to control moderate adolescent idiopathic scoliosis (AIS) from progression. Clinicians may find difficulties in the selection of appropriate interventions for AIS. A comprehensive literature review was carried out to study all contemporary non-operative interventions, it was noted that rigid spinal orthoses apparently give more curve control; however, it would compromise the patient's quality of life via those inevitable factors--physical constraint, poor acceptance and psychological disturbance. There is a trend to develop more effective, acceptable and user-friendly interventions. Under such an aspiration, the theories and clinical evidence of different interventions should be developed along the clinical pathway of early intervention with reliable indicators/predictors, patient's active participation, dynamic control mechanism, holistic psychological and psychosocial considerations, and effective and long-lasting outcome.

Sparse PDF maps for non-linear multi-resolution image operations

KAUST Repository

Hadwiger, Markus

2012-11-01

We introduce a new type of multi-resolution image pyramid for high-resolution images called sparse pdf maps (sPDF-maps). Each pyramid level consists of a sparse encoding of continuous probability density functions (pdfs) of pixel neighborhoods in the original image. The encoded pdfs enable the accurate computation of non-linear image operations directly in any pyramid level with proper pre-filtering for anti-aliasing, without accessing higher or lower resolutions. The sparsity of sPDF-maps makes them feasible for gigapixel images, while enabling direct evaluation of a variety of non-linear operators from the same representation. We illustrate this versatility for antialiased color mapping, O(n) local Laplacian filters, smoothed local histogram filters (e.g., median or mode filters), and bilateral filters. © 2012 ACM.

Non-perturbative renormalization of the chromo-magnetic operator in heavy quark effective theory and the B{sup *} - B mass splitting

Energy Technology Data Exchange (ETDEWEB)

Guazzini, D.; Sommer, R. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Meyer, H. [Massachusetts Institute of Technology, Cambridge, MA (United States). Center for Theoretical Physics

2007-05-15

We carry out the non-perturbative renormalization of the chromo-magnetic operator in Heavy Quark Effective Theory. At order 1/m of the expansion, the operator is responsible for the mass splitting between the pseudoscalar and vector B mesons. We obtain its two-loop anomalous dimension in a Schroedinger functional scheme by successive oneloop conversions to the lattice MS scheme and the MS scheme. We then compute the scale evolution of the operator non-perturbatively in the N{sub f}=0 theory between {mu} {approx}0.3 GeV and {mu} {approx}100 GeV, where contact is made with perturbation theory. The overall renormalization factor that converts the bare lattice operator to its renormalization group invariant form is given for the Wilson gauge action and two standard discretizations of the heavy-quark action. As an application, we find that this factor brings the previous quenched predictions of the B{sup *}-B mass splitting closer to the experimental value than found with a perturbative renormalization. The same renormalization factor is applicable to the spin-dependent potentials of Eichten and Feinberg. (orig.)

40 CFR 257.5 - Disposal standards for owners/operators of non-municipal non-hazardous waste disposal units that...

Science.gov (United States)

2010-07-01

... compliance with §§ 257.7 through 257.30 prior to the receipt of CESQG hazardous waste. (b) Definitions.... Waste management unit boundary means a vertical surface located at the hydraulically downgradient limit.../operators of non-municipal non-hazardous waste disposal units that receive Conditionally Exempt Small...

The temporal course of mucoperiosteal flap revascularization at guided bone regeneration-treated implant sites: a pilot study

NARCIS (Netherlands)

Milstein, Dan M. J.; Mathura, Keshen R.; Lindeboom, Jerôme A. H.; Ramsoekh, Dewkoemar; Lindeboom, Robert; Ince, Can

2009-01-01

P>Aims To investigate post-operative capillary density regeneration in healing mucoperiosteal flaps at guided bone regeneration-treated implant sites. Material and Methods A non-invasive post-operative investigation was performed in 10 patients using orthogonal polarization spectral (OPS) imaging

Comparing cultural profiles of MCR operators with those of non-MCR operators working in domestic Nuclear Power Plants

International Nuclear Information System (INIS)

Park, Jinkyun; Jung, Wondea

2015-01-01

Operation experience of complex socio-technical systems such as Nuclear Power Plants (NPPs) shows that most significant events are attributable to human error. Thus, various kinds of Human Reliability Analysis (HRA) techniques were used to manage human error for safety-critical tasks. However, a lack of available HRA data is a critical issue in conducting an HRA. For this reason, many researchers have tried to provide HRA data extracted from simulated emergency conditions. Unfortunately, it is still doubtful to directly use these HRA data because different operational cultures may result in different human performances even under a similar task context. From this concern, previous studies claimed that Main Control Room (MCR) operators working in different NPPs share very similar cultural profile. In order to confirm this claim, the culture profiles of operating personnel (i.e., non-MCR and MCR operators) working in domestic NPPs are compared. As a result, although some discrepancies are observed, it is positive to say that operating personnel of NPPs share similar cultural profiles to some extent. This result can be regarded as the first step to provide technical underpinnings that are helpful for understanding human performance data collected from different countries. - Highlights: • National and organizational culture of MCR and non-MCR operators are compared. • Organizational culture profiles are almost identical. • National culture profiles are not quite different overall. • Operating personnel in Nuclear Power Plants seems to share similar cultural profiles

Assessment of Biochemical Changes and Protein Pattern in Kidney of Fasciola gigantica. Infected Rabbit Untreated and Treated with Triclabendazole

International Nuclear Information System (INIS)

Moawad, M.A.; Hafez, E.N.

2014-01-01

Fascioliasis is a hepatic parasitic infection caused by Fasciola gigantica that affects numerous mammalian species, mainly ruminants and occasionally human. Triclabendazole TCBZ (marketed as Fasinex) has high efficacy against all stages of F. gigantica in mammalian host. The present study was designed to evaluate the effect of infection on liver and kidney functions in rabbits untreated and treated with triclabendazole and the electrophoretic pattern of proteins of the rabbit kidney as well. Twenty four (24) parasite-free rabbits were divided into four groups, group (1): normal control (non treated, non infected), group (2): infected only, group (3): treated with TBCZ only, group: (4) infected and then treated with TBCZ. Biochemical studies on infected, treated and infected treated showed a high significant hyperbilirubinaemia P<0.001 in infected and treated groups and significant hyperbilirubinaemia P<0.01 in infected treated group compared to the normal control group. Ala - nine aminotransferase (ALT) value was highly significantly increased in infected group P<0.001 with no significant changes (P>0.05) in both treated and infected treated groups compared to control normal group. Aspartate aminotransferase (AST) levels showed high significant increase P>0.001 compared to normal control group. Blood urea levels in infected and treated groups were highly significant increased compared to control normal group with P<0.001. Similarly serum creatinine levels showed high significant increase P<0.001 in both infected and infected treated groups with values (1.4 Mg/dl) and (1.2 Mg/dl) respectively. While only treated group showed significant decrease (0.6 Mg/dl) compared to normal group (0.77 Mg/dl). The concentration of protein bands in kidney electrophoresis revealed no significant changes in pre albumin in infected group (P>0.05) and significant difference in treated and infected treated groups (P<0.01) compared to normal control group. Albumin concentration showed

Association between elevated pre-operative glycosylated hemoglobin and post-operative infections after non-emergent surgery.

Science.gov (United States)

Blankush, Joseph M; Leitman, I Michael; Soleiman, Aron; Tran, Trung

2016-09-01

A chronic state of impaired glucose metabolism affects multiple components of the immune system, possibly leading to an increased incidence of post-operative infections. Such infections increase morbidity, length of stay, and overall cost. This study evaluates the correlation between elevated pre-operative glycosylated hemoglobin (HbA1c) and post-operative infections. Adult patients undergoing non-emergent procedures across all surgical subspecialties from January 2010 to July 2014 had a preoperative HbA1c measured as part of their routine pre-surgical assessment. 2200 patient charts (1100 operative infection (superficial surgical site infection, deep wound/surgical space abscess, pneumonia, and/or urinary tract infection as defined by Centers for Disease Control criteria) within 30 days of surgery. Patients with HbA1c infection rate (3.8% in the HbA1c infection. Elevated HbA1c was, however, predictive of significantly increased risk of post-operative infection when associated with increased age (≥81 years of age) or dirty wounds. The risk factors of post-operative infection are multiple and likely synergistic. While pre-operative HbA1c level is not independently associated with risk of post-operative infection, there are scenarios and patient subgroups where pre-operative HbA1c is useful in predicting an increased risk of infectious complications in the post-operative period.

Sparse PDF maps for non-linear multi-resolution image operations

KAUST Repository

Hadwiger, Markus; Sicat, Ronell Barrera; Beyer, Johanna; Krü ger, Jens J.; Mö ller, Torsten

2012-01-01

feasible for gigapixel images, while enabling direct evaluation of a variety of non-linear operators from the same representation. We illustrate this versatility for antialiased color mapping, O(n) local Laplacian filters, smoothed local histogram filters

Case-mix analysis and variation in rates of non-surgical treatment of older women with operable breast cancer.

Science.gov (United States)

Morgan, J; Richards, P; Ward, S; Francis, M; Lawrence, G; Collins, K; Reed, M; Wyld, L

2015-08-01

Non-surgical management of older women with oestrogen receptor (ER)-positive operable breast cancer is common in the UK, with up to 40 per cent of women aged over 70 years receiving primary endocrine therapy. Although this may be appropriate for frailer patients, for some it may result in treatment failure, contributing to the poor outcomes seen in this age group. Wide variation in the rates of non-operative management of breast cancer in older women exists across the UK. Case mix may explain some of this variation in practice. Data from two UK regional cancer registries were analysed to determine whether variation in treatment observed between 2002 and 2010 at hospital and clinician level persisted after adjustment for case mix. Expected case mix-adjusted surgery rates were derived by logistic regression using the variables age, proxy Charlson co-morbidity score, deprivation quintile, method of cancer detection, tumour size, stage, grade and node status. Data on 17,129 women aged 70 years or more with ER-positive operable breast cancer were analysed. There was considerable variation in rates of surgery at both hospital and clinician level. Despite adjusting for case mix, this variation persisted at hospital level, although not at clinician level. This study demonstrates variation in selection criteria for older women for operative treatment of early breast cancer, indicating that some older women may be undertreated or overtreated, and may partly explain the inferior disease outcomes in this age group. It emphasizes the urgent need for evidence-based guidelines for treatment selection criteria in older women with breast cancer. © 2015 BJS Society Ltd Published by John Wiley & Sons Ltd.

Non-Thermal Treatment of Hanford Site Low-Level Mixed Waste

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-09-01

DOE proposes to transport contact-handled LLMW from the Hanford Site to the Allied Technology Group (ATG) Mixed Waste Facility (MWF) in Richland, Washington, for non-thermal treatment and to return the treated waste to the Hanford Site for eventual land disposal. Over a 3-year period the waste would be staged to the ATG MWF, and treated waste would be returned to the Hanford Site. The ATG MWF would be located on an 18 hectare (ha) (45 acre [at]) ATG Site adjacent to ATG's licensed low-level waste processing facility at 2025 Battelle Boulevard. The ATG MWF is located approximately 0.8 kilometers (km) (0.5 miles [mi]) south of Horn Rapids Road and 1.6 km (1 mi) west of Stevens Drive. The property is located within the Horn Rapids triangle in northern Richland (Figure 2.1). The ATG MWF is to be located on the existing ATG Site, near the DOE Hanford Site, in an industrial area in the City of Richland. The effects of siting, construction, and overall operation of the MWF have been evaluated in a separate State Environmental Policy Act (SEPA) EIS (City of Richland 1998). The proposed action includes transporting the LLMW from the Hanford Site to the ATG Facility, non-thermal treatment of the LLMW at the ATG MWF, and transporting the waste from ATG back to the Hanford Site. Impacts fi-om waste treatment operations would be bounded by the ATG SEPA EIS, which included an evaluation of the impacts associated with operating the non-thermal portion of the MWF at maximum design capacity (8,500 metric tons per year) (City of Richland 1998). Up to 50 employees would be required for non-thermal treatment portion of the MWF. This includes 40 employees that would perform waste treatment operations and 10 support staff. Similar numbers were projected for the thermal treatment portion of the MWF (City of Richland 1998).

Definitive Radiotherapy of Non-Small Cell Lung Cancer

International Nuclear Information System (INIS)

Lee, Jong Young; Park, Kyung Ran

1995-01-01

Purpose : The effect of dose escalation of up to 6500 cGy on local control and survival was investigated in locally advanced non-small cell lung cancer. Materials and Methods : Ninety eight patients with biopsy-proven unresectable non-small cell lung cancer without distant metastases or medically inoperable patients with lower-stage were treated with definitive radiotherapy alone. Group A were treated by thoracic irradiation, 6000 cGy or less in total tumor dose with daily fractions of 180 to 200 cGy: and group B was treated with 6500 cGy of same daily fractions. Results : The actuarial overall survival rate for the entire group was 54% at 1 year, 26.6% at 2 years and 16.4% at 3 years with a median survival time of 13 months. Statistically significant prognostic factors that affect survival rate were stage and N-stage. However, no improvement in local control and survival has been seen with higher dose radiotherapy(group B). Conclusion : Dose escalation of up to 6500 cGy was no effect on local control and survival rate. To increase the survival rate of non-small cell lung cancer hyperfractionated radiotherapy or concurrent chemoradiotherapy should be considered

Non-operative management of blunt splenic injuries in a paediatric population: a 12-year experience.

Science.gov (United States)

Kirkegård, Jakob; Avlund, Tue Højslev; Amanavicius, Nerijus; Mortensen, Frank Viborg; Kissmeyer-Nielsen, Peter

2015-02-01

Non-operative management (NOM) is now the primary treatment for blunt splenic injuries in children. Only one study has examined the use of NOM in a Scandinavian population. Thus, the purpose of this study is to report our experience in treating children with blunt splenic injuries with NOM at a Danish university hospital. We conducted a retrospective observational study of 34 consecutive children (aged 16 years or less) admitted to our level 1-trauma centre with blunt splenic injury in the 12-year period from 1 January 2001 to 31 December 2012. Data on patients and procedures were obtained by review of all medical records and re-evaluation of all initial computed tomographies (CT). We included 34 children with a median age of 10.5 years (67.6% males) in this study. All patients were scheduled for NOM, and two (5.9%) patients underwent splenic artery embolisation (SAE). Two (5.9%) patients later needed surgical intervention. The NOM success rate was 88% (95% confidence interval (CI): 73-97%) without SAE and 94% (95% CI: 80-99%) with SAE. We found no difference in the American Association for the Surgery of Trauma grade when comparing the initial CT evaluation (mean 2.59 ± 1.1) with the CT re-evaluation (mean 2.71 ± 0.94); p = 0.226. We demonstrated a high degree of success and safety of non-operative treatment in children with blunt splenic injury in a Scandinavian setting. Our results are comparable to international findings.

Outcome of sporadic amyotrophic lateral sclerosis treated with non-invasive ventilation and riluzole.

Science.gov (United States)

Sívori, Martín; Rodríguez, Gabriel E; Pascansky, Daniel; Sáenz, César; Sica, Roberto E P

2007-01-01

Sporadic amyotrophic lateral sclerosis (sALS) is a progressive degenerative motor neuron disorder lacking specific treatment. Riluzole is the only drug able to modestly slow down the course of the disease. Respiratory insufficiency is the main cause of death; non invasive ventilation (NIV) has shown to improve survival. Our aim was to evaluate the effect of NIV and riluzole on survival. Ninety seven patients with a diagnosis of sALS were assessed and followed up for 60 months. Twenty nine patients received NIV and 68 did not (nNIV). Overall median survival In the NIV group was 15.41 +/- 7.78 months vs. 10.88 +/- 7.78 months in the nNIV group (p= 0.028). Median survival time was not different in patients receiving riluzole (n=44), as compared with those who did not (n=53), although at month 4th and 5th riluzole treated patients showed a modest benefit. In those who only received NIV (n=11) or only riluzole (n=26), survival time was 13.45 +/- 13.44 months and 11.19 +/- 7.79 months, respectively. Patients who received both NIV and riluzole (n=18) had a median survival time of 16.61 +/- 10.97 months vs. 10.69 +/- 7.86 months for those who received only supportive treatment (n=42) (p= 0.021). NIV improved survival in our series of patients. Riluzole did not show any significant impact on survival when employed as the only therapy. Patients receiving both treatments simultaneously had a significant longer survival.

Modern oncologic and operative outcomes for oesophageal cancer treated with curative intent.

LENUS (Irish Health Repository)

Reynolds, J V

2011-09-01

The curative approach to oesophageal cancer carries significant risks and a cure is achieved in approximately 20 per cent. There has been a recent trend internationally to observe improved operative and oncological outcomes. This report audits modern outcomes from a high volume centre with a prospective database for the period 2004-08. 603 patients were referred and 310 (52%) were treated with curative intent. Adenocarcinoma represented 68% of the cohort, squamous cell cancer 30%. Of the 310 cases, 227 (73%) underwent surgery, 105 (46%) underwent surgery alone, and 122 (54%) had chemotherapy or combination chemotherapy and radiation therapy. The postoperative mortality rate was 1.7%. The median and 5-year survival of the 310 patients based on intention to treat was 36 months and 36%, respectively, and of the 181 patients undergoing R0 resection, 52 months and 42%, respectively. An in-hospital postoperative mortality rate of less than 2 per cent, and 5-year survival of between 35 and 42% is consistent with benchmarks from international series.

Operator performance in non-destructive testing: A study of operator performance in a performance test

Energy Technology Data Exchange (ETDEWEB)

Enkvist, J.; Edland, A.; Svenson, Ola [Stockholm Univ. (Sweden). Dept. of Psychology

2000-05-15

In the process industries there is a need of inspecting the integrity of critical components without disrupting the process. Such in-service inspections are typically performed with non-destructive testing (NDT). In NDT the task of the operator is to (based on diagnostic information) decide if the component can remain in service or not. The present study looks at the performance in NDT. The aim is to improve performance, in the long run, by exploring the operators' decision strategies and other underlying factors and to this way find out what makes some operators more successful than others. Sixteen operators performed manual ultrasonic inspections of four test pieces with the aim to detect (implanted) cracks. In addition to these performance demonstration tests (PDT), the operators performed independent ability tests and filled out questionnaires. The results show that operators who trust their gut feeling more than the procedure (when the two come to different results) and that at the same time have a positive attitude towards the procedure have a higher PDT performance. These results indicate the need for operators to be motivated and confident when performing NDT. It was also found that the operators who performed better rated more decision criteria higher in the detection phase than the operators who performed worse. For characterizing it was the other way around. Also, the operators who performed better used more time, both detecting and characterizing, than the operators who performed worse.

Operator performance in non-destructive testing: A study of operator performance in a performance test

International Nuclear Information System (INIS)

Enkvist, J.; Edland, A.; Svenson, Ola

2000-05-01

In the process industries there is a need of inspecting the integrity of critical components without disrupting the process. Such in-service inspections are typically performed with non-destructive testing (NDT). In NDT the task of the operator is to (based on diagnostic information) decide if the component can remain in service or not. The present study looks at the performance in NDT. The aim is to improve performance, in the long run, by exploring the operators' decision strategies and other underlying factors and to this way find out what makes some operators more successful than others. Sixteen operators performed manual ultrasonic inspections of four test pieces with the aim to detect (implanted) cracks. In addition to these performance demonstration tests (PDT), the operators performed independent ability tests and filled out questionnaires. The results show that operators who trust their gut feeling more than the procedure (when the two come to different results) and that at the same time have a positive attitude towards the procedure have a higher PDT performance. These results indicate the need for operators to be motivated and confident when performing NDT. It was also found that the operators who performed better rated more decision criteria higher in the detection phase than the operators who performed worse. For characterizing it was the other way around. Also, the operators who performed better used more time, both detecting and characterizing, than the operators who performed worse

POSITIVE study: physical exercise program in non-operable lung cancer patients undergoing palliative treatment.

Science.gov (United States)

Wiskemann, Joachim; Hummler, Simone; Diepold, Christina; Keil, Melanie; Abel, Ulrich; Steindorf, Karen; Beckhove, Philipp; Ulrich, Cornelia M; Steins, Martin; Thomas, Michael

2016-07-19

Patients with advanced stage non-small cell lung cancer (NSCLC) or small cell lung cancer (SCLC) often experience multidimensional impairments, affecting quality of life during their course of disease. In lung cancer patients with operable disease, several studies have shown that exercise has a positive impact on quality of life and physical functioning. There is limited evidence regarding efficacy for advanced lung cancer patients undergoing palliative treatment. Therefore, the POSITIVE study aims to evaluate the benefit of a 24-week exercise intervention during palliative treatment in a randomized controlled setting. The POSITIVE study is a randomized, controlled trial investigating the effects of a 24-week exercise intervention during palliative treatment on quality of life, physical performance and immune function in advanced, non-operable lung cancer patients. 250 patients will be recruited in the Clinic for Thoracic Diseases in Heidelberg, enrolment begun in November 2013. Main inclusion criterion is histologically confirmed NSCLC (stage IIIa, IIIb, IV) or SCLC (Limited Disease-SCLC, Extensive Disease-SCLC) not amenable to surgery. Patients are randomized into two groups. Both groups receive weekly care management phone calls (CMPCs) with the goal to assess symptoms and side effects. Additionally, one group receives a combined resistance and endurance training (3x/week). Primary endpoints are quality of life assessed by the Functional Assessment of Cancer Therapy for patients with lung cancer (FACT-L, subcategory Physical Well-Being) and General Fatigue measured by the Multidimensional Fatigue Inventory (MFI-20). Secondary endpoints are physical performance (maximal voluntary isometric contraction, 6-min walk distance), psychosocial (depression and anxiety) and immunological parameters and overall survival. The aim of the POSITIVE trial is the evaluation of effects of a 24-week structured and guided exercise intervention during palliative treatment stages

Analysis of toxicity in a group of patients treated for pancreatic cancer with combined modality 3D radiation therapy

International Nuclear Information System (INIS)

Fine, Robert M.; Fernandez-Vicioso, Eduardo; Higgins, Patrick; Schell, Michael; Sohn, Jason; Pelley, Robert; Walsh, R. M.; Vogt, David; Hermann, Robert

1995-01-01

Purpose: To evaluate the acute toxicity of a group of 37 pancreatic cancer patients treated with noncoplanar, nonopposed, conformal radiation therapy with concurrent chemotherapy (5-FU). Materials and Methods: We retrospectively evaluated a group of initially nonadvanced 37 pancreatic cancer patients treated with combined concurrent chemotherapy and 3D radiation therapy treated between 1992 until 1995. During this period we began treating the initially unresectable patients with preoperative chemo-RT (50.4 Gy) after treating an initial group of unresectable patients to a higher dose of 66.6 Gy. We also include a group of patients who received postop chemo-RT after Whipple resection (59.4 Gy). All radiation was delivered at a 1.8 Gy per fraction dose rate. The total group was made up of 37 patients of whom 21 were male (57%) and 16 female (43%). There were 22 (59%) head of pancreas lesions, 10 (27%) body of pancreas lesions, and 5 (14%) head and body of pancreas cancers. Of these 37 patients 7 (19%) were treated with chemo-RT as their only treatment, 10 patients (29%) were treated post Whipple resection, and 20 patients (54%) were treated with preoperative intent. Results: Three patients (8%) required a treatment break, one with a body and 2 with head lesions. Two of these patients stopped RT short of planned dose (32.56 and 46.8 Gy) both suffering from nausea, vomiting, and anorexia with the third, who finished a planned 66.6 Gy dose, after a 4 day rest for leukopenia. One of 20 patients (5%) preop patients underwent the planned post chemo-RT Whipple resection, while 4 of the 20 patients (20%), remained unresectable, but without disease progression and had Iodine 125 interstitial implants at exploration delivering a minimal tumor dose of 120 Gy on top or the 50.4 Gy delivered preoperatively. Four patients (11%) maintained a minimal Karnofsky score of 100, 23 patients (62%) maintained a minimal KPS of 90, 6 patients (16%) maintained a minimal KPS of 80, and 4

Non-uniform hybrid strategy for architecting and modeling flight vehicle focused system-of-systems operations

Directory of Open Access Journals (Sweden)

Tian Yifeng

2016-02-01

Full Text Available To balance the contradiction between comprehensiveness of system-of-systems (SoS description and cost of modeling and simulation, a non-uniform hybrid strategy (NUHYS is proposed. NUHYS groups elements of an SoS operation into system community or relatively independent system based on contributors complexity and focus relationship according to the focus of SoS problem. Meanwhile, modeling methods are categorized based on details attention rate and dynamic attention rate, seeking for matching contributors. Taking helicopter rescue in earthquake relief as an example, the procedure of applying NUHYS and its effectiveness are verified.

Generalized dilatation operator method for non-relativistic holography

Energy Technology Data Exchange (ETDEWEB)

Chemissany, Wissam, E-mail: wissam@stanford.edu [Department of Physics and SITP, Stanford University, Stanford, CA 94305 (United States); Papadimitriou, Ioannis, E-mail: ioannis.papadimitriou@csic.es [Instituto de Física Teórica UAM/CSIC, Universidad Autónoma de Madrid, Madrid 28049 (Spain)

2014-10-07

We present a general algorithm for constructing the holographic dictionary for Lifshitz and hyperscaling violating Lifshitz backgrounds for any value of the dynamical exponent z and any value of the hyperscaling violation parameter θ compatible with the null energy condition. The objective of the algorithm is the construction of the general asymptotic solution of the radial Hamilton–Jacobi equation subject to the desired boundary conditions, from which the full dictionary can be subsequently derived. Contrary to the relativistic case, we find that a fully covariant construction of the asymptotic solution for running non-relativistic theories necessitates an expansion in the eigenfunctions of two commuting operators instead of one. This provides a covariant but non-relativistic grading of the expansion, according to the number of time derivatives.

Effectiveness and environmental considerations for non-dispersant chemical countermeasures

International Nuclear Information System (INIS)

Walker, A.H.; Kucklick, J.H.; Michel, J.

1999-01-01

Mechanical countermeasures for oil spill response have various effectiveness and operational limitations under certain spill situations. This has led to an interest in and use of alternative treatment methods. This chapter reviews the potential utility of one such group, nondispersant chemical countermeasures, in controlling the adverse impacts from marine oil spills. The types of nondispersant chemical countermeasures presented here include: herding agents, emulsion treating agents, solidifiers, elasticity modifiers, and shoreline cleaning agents. Each countermeasure group is discussed separately to provide a definition, mechanism of action, and effectiveness and environmental considerations for the group. Where ever possible, examples are given of countermeasure use during an actual spill. In addition to the groups mentioned above, a few other treating agents are briefly described under the section 'Miscellaneous Agents' to illustrate other, less prominent types of chemical countermeasures. Non-dispersant chemical countermeasures appear to have discrete response niches, i.e. situations where the countermeasures are well-suited and offer potential benefits. The key is matching conditions for optimal effectiveness with the appropriate incident-specific characteristics and window of opportunity. The practical aspects of logistics are not addressed because, if their potential utility can be demonstrated, the resolution of these issues would follow. (author)

Nehari manifold for non-local elliptic operator with concave–convex ...

Indian Academy of Sciences (India)

Introduction. We consider the following p-fractional Laplace equation ... ators of elliptic type due to concrete real world applications in finance, thin obstacle .... Due to the non-localness of the operator LK, we define the linear space as follows:.

Preliminary Study on Non-Fatal Occupational Injury among Operational Workers in Malaysia Palm Oil Mill

Directory of Open Access Journals (Sweden)

Ruslan Rumaizah

2017-01-01

Full Text Available Non-fatal occupational injury had becoming major global concern and its consequences to safety and health would be heavily burdening. The aim of this preliminary study was to investigate the distribution of non-fatal occupational injury among specific group of workers in palm oil mill and to acknowledge potential factors of injury causation. A questionnaire survey was designed to assess injury involvement during the employment period among operational workers of palm oil mill located in Southern Peninsular Malaysia. Thirty three (n= 33 workers volunteered and completed the questionnaire. Prevalence of injury among palm oil mill workers was 39.4% with sprain and burn were the common types of injury reported. Press Plant workers reported to have high cases of injuries. Majority of workers (78.8% stated noise was the main hazard in the palm oil mill, followed by heat hazard. Press Plant was identified as one of the specific risk group in palm oil mill based on the rate of injury occurrences reported by the workers. Exposure to noise hazard was estimated to be one of the potential factors of injury causation and further study should be made to measure the risk of hazard.

Treatment technologies for non-high-level wastes (USA)

International Nuclear Information System (INIS)

Cooley, C.R.; Clark, D.E.

1976-06-01

Non-high-level waste arising from operations at nuclear reactors, fuel fabrication facilities, and reprocessing facilities can be treated using one of several technical alternatives prior to storage. Each alternative and the associated experience and status of development are summarized. The technology for treating non-high-level wastes is generally available for industrial use. Improved techniques applicable to the commercial nuclear fuel cycle are being developed and demonstrated to reduce the volume of waste and to immobilize it for storage. 36 figures, 59 references

Canonical construction of differential operators intertwining representations of real semisimple Lie groups

International Nuclear Information System (INIS)

Dobrev, V.K.

1986-11-01

Let G be a real linear connected semisimple Lie group. We present a canonical construction of the differential operators intertwining elementary (≡ generalized principal series) representations of G. The results are easily extended to real linear reductive Lie groups. (author). 20 refs

The Unbalanced Linguistic Aggregation Operator in Group Decision Making

Directory of Open Access Journals (Sweden)

Li Zou

2012-01-01

Full Text Available Many linguistic aggregation methods have been proposed and applied in the linguistic decision-making problems. In practice, experts need to assess a number of values in a side of reference domain higher than in the other one; that is, experts use unbalanced linguistic values to express their evaluation for problems. In this paper, we propose a new linguistic aggregation operator to deal with unbalanced linguistic values in group decision making, we adopt 2-tuple representation model of linguistic values and linguistic hierarchies to express unbalanced linguistic values, and moreover, we present the unbalanced linguistic ordered weighted geometric operator to aggregate unbalanced linguistic evaluation values; a comparison example is given to show the advantage of our method.

Evaluation of the effects of a therapeutic renal diet to control proteinuria in proteinuric non-azotemic dogs treated with benazepril.

Science.gov (United States)

Cortadellas, O; Talavera, J; Fernández del Palacio, M J

2014-01-01

Angiotensin-converting enzyme inhibitors (ACEIs) are currently used to control proteinuria in dogs with chronic kidney disease. Renal diets (RDs) have beneficial effects in the management of azotemic dogs, but its role in proteinuric non-azotemic (PNAz) dogs has been poorly documented. Administration of a RD to PNAz dogs treated with benazepril (Be) improves proteinuria control compared with the administration of a maintenance diet (MD). Twenty-two PNAz (urine protein/creatinine ratio [UPC] >1) dogs. Randomized open label clinical trial design. Dogs were assigned to group-MD (5.5 g protein/100 kcal ME)/Be or to group-RD (3.7 g protein/100 kcal ME)/Be group during 60 days. Dogs with serum albumin (Alb) <2 g/dL received aspirin (1 mg/kg/12 hours). A physical examination, systolic blood pressure (SBP) measurement, complete blood count (CBC), biochemistry panel, urinalysis, and UPC were performed at day 0 (D0) and day 60 (D60). At D0, there were no significant differences between groups in the evaluated variables. During the study, logUPC (geometric mean (95% CI) and SBP (mean±SD mmHg) significantly decreased (paired t-test, P = 0.001) in Group-RD (logUPC(D0) = 3.16[1.9-5.25]; UPC(D60) = 1.20 [0.59-2.45]; SBP(D0) = 160 ± 17.2; SBP(D60) = 151 ± 15.8), but not in Group-MD (UPC(D0) = 3.63[2.69-4.9]; UPC(D60) = 2.14 [0.76-6.17]; SBP(D0) = 158 ± 14.7; SBP(D60) = 153 ± 11.5). However, RM-ANOVA test did not confirm that changes were consequence of dietary modification. Weight and Alb concentration did not change significantly in any group. The administration of a RD to PNAz dogs treated with Be might help to control proteinuria and SBP compared with the administration of a MD, without inducing clinically detectable malnutrition, but more studies are warranted. Copyright © 2013 by the American College of Veterinary Internal Medicine.

Coherence and Coupling Functions Reveal Microvascular Impairment in Treated Hypertension

Directory of Open Access Journals (Sweden)

Valentina Ticcinelli

2017-10-01

Full Text Available The complex interactions that give rise to heart rate variability (HRV involve coupled physiological oscillators operating over a wide range of different frequencies and length-scales. Based on the premise that interactions are key to the functioning of complex systems, the time-dependent deterministic coupling parameters underlying cardiac, respiratory and vascular regulation have been investigated at both the central and microvascular levels. Hypertension was considered as an example of a globally altered state of the complex dynamics of the cardiovascular system. Its effects were established through analysis of simultaneous recordings of the electrocardiogram (ECG, respiratory effort, and microvascular blood flow [by laser Doppler flowmetry (LDF]. The signals were analyzed by methods developed to capture time-dependent dynamics, including the wavelet transform, wavelet-based phase coherence, non-linear mode decomposition, and dynamical Bayesian inference, all of which can encompass the inherent frequency and coupling variability of living systems. Phases of oscillatory modes corresponding to the cardiac (around 1.0 Hz, respiratory (around 0.25 Hz, and vascular myogenic activities (around 0.1 Hz were extracted and combined into two coupled networks describing the central and peripheral systems, respectively. The corresponding spectral powers and coupling functions were computed. The same measurements and analyses were performed for three groups of subjects: healthy young (Y group, 24.4 ± 3.4 y, healthy aged (A group, 71.1 ± 6.6 y, and aged treated hypertensive patients (ATH group, 70.3 ± 6.7 y. It was established that the degree of coherence between low-frequency oscillations near 0.1 Hz in blood flow and in HRV time series differs markedly between the groups, declining with age and nearly disappearing in treated hypertension. Comparing the two healthy groups it was found that the couplings to the cardiac rhythm from both respiration and

Non-technical skills of surgeons and anaesthetists in simulated operating theatre crises.

Science.gov (United States)

Doumouras, A G; Hamidi, M; Lung, K; Tarola, C L; Tsao, M W; Scott, J W; Smink, D S; Yule, S

2017-07-01

Deficiencies in non-technical skills (NTS) have been increasingly implicated in avoidable operating theatre errors. Accordingly, this study sought to characterize the impact of surgeon and anaesthetist non-technical skills on time to crisis resolution in a simulated operating theatre. Non-technical skills were assessed during 26 simulated crises (haemorrhage and airway emergency) performed by surgical teams. Teams consisted of surgeons, anaesthetists and nurses. Behaviour was assessed by four trained raters using the Non-Technical Skills for Surgeons (NOTSS) and Anaesthetists' Non-Technical Skills (ANTS) rating scales before and during the crisis phase of each scenario. The primary endpoint was time to crisis resolution; secondary endpoints included NTS scores before and during the crisis. A cross-classified linear mixed-effects model was used for the final analysis. Thirteen different surgical teams were assessed. Higher NTS ratings resulted in significantly faster crisis resolution. For anaesthetists, every 1-point increase in ANTS score was associated with a decrease of 53·50 (95 per cent c.i. 31·13 to 75·87) s in time to crisis resolution (P technical skills scores were lower during the crisis phase of the scenarios than those measured before the crisis for both surgeons and anaesthetists. A higher level of NTS of surgeons and anaesthetists led to quicker crisis resolution in a simulated operating theatre environment. © 2017 BJS Society Ltd Published by John Wiley & Sons Ltd.

Annual Summary Report, February to December 1998, for the 100-HR-3 and 100-KR-4 Pump-and-Treat Operations and Operable Units

International Nuclear Information System (INIS)

Boutin, R. J.

1999-01-01

This annual summary report discusses the interim remedial actions at the 100-HR-3 and 100-KR-4 Operable Units (OUs) for February 1,1998, through December 31, 1998. This is the second annual summary report that has been submitted for these OUs; the first report was released in April 1998 (DOE-RL 1998). Ongoing annual summaries and performance evaluations of each of the pump-and-treat systems are required by the Remedial Design Report and Remedial Action Work Plan for the 100-HR-3 and 100-KR-4 Groundwater Operable Units' Interim Action (RDR/RAWP) (DOE-RL 1996)

Invariance Lie algebra and group of the non relativistic hydrogen atom

International Nuclear Information System (INIS)

Decoster, Alain

1970-01-01

The first part of this work contains a general survey of the use of Lie groups and algebras in quantum mechanics, followed by an extensive description of tbe invariance algebra and invariance group of the non-relativistic hydrogen atom; the realization of this group discovered by FOCK is specially examined. The second part is a two-hundred items bibliography on invariance groups and algebras of classical and quantum-mechanical simple systems. (author) [fr

Comparison of Survival Rate in Primary Non-Small-Cell Lung Cancer Among Elderly Patients Treated With Radiofrequency Ablation, Surgery, or Chemotherapy

International Nuclear Information System (INIS)

Lee, Heon; Jin, Gong Yong; Han, Young Min; Chung, Gyung Ho; Lee, Yong Chul; Kwon, Keun Sang; Lynch, David

2012-01-01

Purpose: We retrospectively compared the survival rate in patients with non-small-cell lung cancer (NSCLC) treated with radiofrequency ablation (RFA), surgery, or chemotherapy according to lung cancer staging. Materials and Methods: From 2000 to 2004, 77 NSCLC patients, all of whom had WHO performance status 0–2 and were >60 years old, were enrolled in a cancer registry and retrospectively evaluated. RFA was performed on patients who had medical contraindications to surgery/unsuitability for surgery, such as advanced lung cancer or refusal of surgery. In the RFA group, 40 patients with inoperable NSCLC underwent RFA under computed tomography (CT) guidance. These included 16 patients with stage I to II cancer and 24 patients with stage III to IV cancer who underwent RFA in an adjuvant setting. In the comparison group (n = 37), 13 patients with stage I to II cancer underwent surgery; 18 patients with stage III to IV cancer underwent chemotherapy; and 6 patients with stage III to IV cancer were not actively treated. The survival curves for RFA, surgery, and chemotherapy in these patients were calculated using Kaplan–Meier method. Results: Median survival times for patients treated with (1) surgery alone and (2) RFA alone for stage I to II lung cancer were 33.8 and 28.2 months, respectively (P = 0.426). Median survival times for patients treated with (1) chemotherapy alone and (2) RFA with chemotherapy for stage III to IV cancer were 29 and 42 months, respectively (P = 0.03). Conclusion: RFA can be used as an alternative treatment to surgery for older NSCLC patients with stage I to II inoperable cancer and can play a role as adjuvant therapy with chemotherapy for patients with stage III to IV lung cancer.

Effects of bestatin on the host immunity in patients treated for urogenital cancer

International Nuclear Information System (INIS)

Ozono, S.; Iwai, A.; Babaya, K.; Hiramatsu, T.; Yoshida, K.; Yamada, K.; Hirao, Y.; Aoyama, H.; Ohara, S.; Okajima, E.

1990-01-01

To examine effects of bestatin on the host immunity of patients with urogenital cancer, 54 patients were randomized into 2 groups: bestatin treated and controls. In each group, the patients were divided into 2 subgroups: one which received basic treatment expected to greatly affect host immunity ('invasive treatment') while the other one received other types of basic treatment ('non-invasive treatment'). Peripheral lymphocyte, OKT 4/8 ratio and purified protein derivative (PPD) skin reaction were used as immunological markers. There were significant differences in the 'invasive' treatment group between bestatin treated patients and controls concerning lymphocyte counts and PPD skin reactions and in the 'non-invasive' group concerning lymphocyte counts and OKT 4/8 ratios. These results suggest that bestatin may potentiate host immunity in patients with urogenital cancer. Further studies on larger materials are, however, needed before more definite conclusions can be drawn. (orig.)

Patterns of Mortality in Patients Treated with Dental Implants: A Comparison of Patient Age Groups and Corresponding Reference Populations.

Science.gov (United States)

Jemt, Torsten; Kowar, Jan; Nilsson, Mats; Stenport, Victoria

2015-01-01

Little is known about the relationship between implant patient mortality compared to reference populations. The aim of this study was to report the mortality pattern in patients treated with dental implants up to a 15-year period, and to compare this to mortality in reference populations with regard to age at surgery, sex, and degree of tooth loss. Patient cumulative survival rate (CSR) was calculated for a total of 4,231 treated implant patients from a single clinic. Information was based on surgical registers in the clinic and the National Population Register in Sweden. Patients were arranged into age groups of 10 years, and CSR was compared to that of the reference population of comparable age and reported in relation to age at surgery, sex, and type of jaw/dentition. A similar, consistent, general relationship between CSR of different age groups of implant patients and reference populations could be observed for all parameters studied. Completely edentulous patients presented higher mortality than partially edentulous patients (P age groups showed mortality similar to or higher than reference populations, while older patient age groups showed increasingly lower mortality than comparable reference populations for edentulous and partially edentulous patients (P age groups of patients compared to reference populations was observed, indicating higher patient mortality in younger age groups and lower in older groups. The reported pattern is not assumed to be related to implant treatment per se, but is assumed to reflect the variation in general health of a selected subgroup of treated implant patients compared to the reference population in different age groups.

Operative management versus non-operative management of rib fractures in flail chest injuries: a systematic review

NARCIS (Netherlands)

Schuurmans, Jaap; Goslings, J. C.; Schepers, T.

2017-01-01

Flail chest is a life-threatening complication of severe chest trauma with a mortality rate of up to 15 %. The standard non-operative management has high comorbidities with pneumonia and often leads to extended Intensive Care Unit (ICU) stay, due to insufficient respiratory function and

Nasal symptoms and clinical findings in adult patients treated for unilateral cleft lip and palate.

Science.gov (United States)

Morén, Staffan; Mani, Maria; Lundberg, Kristina; Holmström, Mats

2013-10-01

The aim of the study was to investigate self-experienced nasal symptoms among adults treated for UCLP and the association to clinical findings, and to evaluate whether palate closure in one-stage or two-stages affected the symptoms or clinical findings. All people with UCLP born between 1960-1987, treated at Uppsala University Hospital, were considered for participation in this cross-sectional population study with long-term follow-up. Eighty-three patients (76% participation rate) participated, a mean of 37 years after the first operation. Fifty-two patients were treated with one-stage palate closure and 31 with two-stage palate closure. An age-matched group of 67 non-cleft controls completed the same study protocol, which included a questionnaire regarding nasal symptoms, nasal inspection, anterior rhinoscopy, and nasal endoscopy. Patients reported a higher frequency of nasal symptoms compared with the control group, e.g., nasal obstruction (81% compared with 60%) and mouth breathing (20% compared with 5%). Patients also rated their nasal symptoms as having a more negative impact on their daily life and physical activities than controls. Nasal examination revealed higher frequencies of nasal deformities among patients. No positive correlation was found between nasal symptoms and severity of findings at nasal examination. No differences were identified between patients treated with one-stage and two-stage palate closure regarding symptoms or nasal findings. Adult patients treated for UCLP suffer from more nasal symptoms than controls. However, symptoms are not associated with findings at clinical nasal examination or method of palate closure.

Symplectic Group Representation of the Two-Mode Squeezing Operator in the Coherent State Basis

Science.gov (United States)

Fan, Hong-Yi; Chen, Jun-Hua

2003-11-01

We find that the coherent state projection operator representation of the two-mode squeezing operator constitutes a loyal group representation of symplectic group, which is a remarkable property of the coherent state. As a consequence, the resultant effect of successively applying two-mode squeezing operators are equivalent to a single squeezing in the two-mode Fock space. Generalization of this property to the 2n-mode case is also discussed. The project supported by National Natural Science Foundation of China under Grant No. 10575057

A new low-cost negative-pressure wound therapy versus a commercially available therapy device widely used to treat complex traumatic injuries: a prospective, randomized, non-inferiority trial

Directory of Open Access Journals (Sweden)

Fabio Kamamoto

Full Text Available OBJECTIVES: Negative-pressure wound therapy has been widely adopted to reduce the complexity of treating a broad range of acute and chronic wounds. However, its cost is high. The objective of this study was to evaluate the following two different methods of negative-pressure wound therapy in terms of healing time: a low-cost method of negative-pressure wound therapy (a pressure stabilizer device connected to a hospital wall-vacuum system with a gauze-sealed dressing, USP and the standard of care (vacuum-assisted closure, VAC. METHODS: This is a randomized, controlled, non-inferiority, unblinded trial. Patients admitted with complex injuries to a trauma center in a public referral hospital who were indicated for orthopedic surgery were randomized to a USP or VAC group. The primary outcome was the time required to achieve a “ready for surgery condition”, which was defined as a wound bed with healthy granulation tissue and without necrosis or purulent secretion. Wound bed area contraction, granulation tissue growth and the direct costs of the dressings were secondary outcomes. RESULTS: Variation in area and granulation tissue growth were essentially the same between the systems, and healing time was equal between the groups (p=0.379. In both systems, serial debridement increased wound area (p=0.934, and granulation tissue was also increased (p=0.408. The mean treatment cost was US$ 15.15 in the USP group and US$ 872.59 in the VAC group. CONCLUSIONS: For treating complex traumatic injuries, USP was non-inferior to and less expensive than VAC.

A new low-cost negative-pressure wound therapy versus a commercially available therapy device widely used to treat complex traumatic injuries: a prospective, randomized, non-inferiority trial.

Science.gov (United States)

Kamamoto, Fabio; Lima, Ana Lucia Munhoz; Rezende, Marcelo Rosa de; Mattar-Junior, Rames; Leonhardt, Marcos de Camargo; Kojima, Kodi Edson; Santos, Carla Chineze Dos

2017-12-01

Negative-pressure wound therapy has been widely adopted to reduce the complexity of treating a broad range of acute and chronic wounds. However, its cost is high. The objective of this study was to evaluate the following two different methods of negative-pressure wound therapy in terms of healing time: a low-cost method of negative-pressure wound therapy (a pressure stabilizer device connected to a hospital wall-vacuum system with a gauze-sealed dressing, USP) and the standard of care (vacuum-assisted closure, VAC). This is a randomized, controlled, non-inferiority, unblinded trial. Patients admitted with complex injuries to a trauma center in a public referral hospital who were indicated for orthopedic surgery were randomized to a USP or VAC group. The primary outcome was the time required to achieve a "ready for surgery condition", which was defined as a wound bed with healthy granulation tissue and without necrosis or purulent secretion. Wound bed area contraction, granulation tissue growth and the direct costs of the dressings were secondary outcomes. Variation in area and granulation tissue growth were essentially the same between the systems, and healing time was equal between the groups (p=0.379). In both systems, serial debridement increased wound area (p=0.934), and granulation tissue was also increased (p=0.408). The mean treatment cost was US$ 15.15 in the USP group and US$ 872.59 in the VAC group. For treating complex traumatic injuries, USP was non-inferior to and less expensive than VAC.

Histologic and inflammatory lamellar changes in horses with oligofructose-induced laminitis treated with a CXCR1/2 antagonist

Directory of Open Access Journals (Sweden)

Leonardo R. de Lima

2016-01-01

Full Text Available Abstract: With the hypothesis that blocking chemokine signaling can ameliorate acute laminitis, the aim was to evaluate the therapeutic effect of intravenous DF1681B, a selective antagonist for CXCR1 and CXCR2 (chemokine receptors, in an oligofructose equine laminitis model. To twelve mixed breed clinically healthy hoses with no previous history of hoof-related lameness was administered oligofructose (10g/kg given by nasogastric tube and divided into two groups: treated (intravenous DF1681B at 30mg/kg 6, 12, 18, and 24h after oligofructose and non-treated groups. Laminar biopsies were performed before and 12, 36, and 72h after administering oligofructose. Samples were stained with periodic acid-Schiff (PAS and scored from 0 to 6 according to epidermal cell and basal membrane changes. The IL-1β, IL-6, and CXCL1 RNA expressions were determined by RT-PCR. Parametric and non-parametric tests were used to compare times within each group (P<0.05. The PAS grades and IL-1β and IL-6 RNA expression increased in the non-treated group, but remained constant in the treated horses. In conclusion, DF1681B therapy reduced laminar inflammation and epidermal deterioration in treated horses. CXCR1/2 blockage should be considered therapeutically for equine acute laminitis.

Performance values for non destructive assay (NDA) techniques applied to safeguards: the 2002 evaluation by the ESARDA NDA Working Group

International Nuclear Information System (INIS)

Guardini, S.

2003-01-01

The first evaluation of NDA performance values undertaken by the ESARDA Working Group for Standards and Non Destructive Assay Techniques (WGNDA) was published in 1993. Almost 10 years later the Working Group decided to review those values, to report about improvements and to issue new performance values for techniques which were not applied in the early nineties, or were at that time only emerging. Non-Destructive Assay techniques have become more and more important in recent years, and they are used to a large extent in nuclear material accountancy and control both by operators and control authorities. As a consequence, the performance evaluation for NDA techniques is of particular relevance to safeguards authorities in optimising Safeguards operations and reducing costs. Performance values are important also for NMAC regulators, to define detection levels, limits for anomalies, goal quantities and to negotiate basic audit rules. This paper presents the latest evaluation of ESARDA Performance Values (EPVs) for the most common NDA techniques currently used for the assay of nuclear materials for Safeguards purposes. The main topics covered by the document are: techniques for plutonium bearing materials: PuO 2 and MOX; techniques for U-bearing materials; techniques for U and Pu in liquid form; techniques for spent fuel assay. This issue of the performance values is the result of specific international round robin exercises, field measurements and ad hoc experiments, evaluated and discussed in the ESARDA NDA Working Group. (author)

43 CFR 404.40 - What is the non-Federal share of operation, maintenance, and replacement costs?

Science.gov (United States)

2010-10-01

... Cost-Sharing § 404.40 What is the non-Federal share of operation, maintenance, and replacement costs? You are required to pay 100 percent of the operation, maintenance, and replacement costs of any rural... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false What is the non-Federal share of operation...

[Attitudes to smoking and characteristics of the habit among a group of young asthmatics compared to a group of non-asthmatics].

Science.gov (United States)

de Granda Orive, J I; Peña Miguel, T; Reinares Ten, C; González Quijada, S; Escobar Sacristán, J; Sáez Valls, R; Herrera de la Rosa, A

2000-03-01

To compare the attitudes toward smoking and smoking patterns of young male asthmatics with the attitudes and habits of a group previously studied non-asthmatic men. Volunteers responded individually to as anonymous questionnaire. Responses were received from 488 asthmatics men (55.83%) of the sample, with 11 not responding) and 386 non-asthmatics (44.16%, with 27 not responding). The mean age of subjects was 19.91 +/- 2.76 yr. Smoking asthmatics numbered 154 (31.56%) non-asthmatic smokers numbered 207 (53.6%) (p non-smoking asthmatics. The prevalence of smoking is lower among asthmatics than among non-asthmatics and asthmatics smoke fewer cigarettes/day and have a lower level of addiction. There are no differences in age of or reasons for starting to smoke. Asthmatics have fewer smoking friends than do non-asthmatics and non-smoking asthmatics have fever still. the desire to quit smoking is high in both groups.

Intensive group training protocol versus guideline physiotherapy for patients with chronic low back pain: a randomised controlled trial.

Science.gov (United States)

van der Roer, Nicole; van Tulder, Maurits; Barendse, Johanna; Knol, Dirk; van Mechelen, Willem; de Vet, Henrica

2008-09-01

Intensive group training using principles of graded activity has been proven to be effective in occupational care for workers with chronic low back pain. Objective of the study was to compare the effects of an intensive group training protocol aimed at returning to normal daily activities and guideline physiotherapy for primary care patients with non-specific chronic low back pain. The study was designed as pragmatic randomised controlled trial with a setup of 105 primary care physiotherapists in 49 practices and 114 patients with non-specific low back pain of more than 12 weeks duration participated in the study. In the intensive group training protocol exercise therapy, back school and operant-conditioning behavioural principles are combined. Patients were treated during 10 individual sessions along 20 group sessions. Usual care consisted of physiotherapy according to the Dutch guidelines for Low Back Pain. Main outcome measures were functional disability (Roland Morris disability questionnaire), pain intensity, perceived recovery and sick leave because of low back pain assessed at baseline and after 6, 13, 26 and 52 weeks. Both an intention-to-treat analysis and a per-protocol analysis were performed. Multilevel analysis did not show significant differences between both treatment groups on any outcome measures during the complete follow-up period, with one exception. After 26 weeks the protocol group showed more reduction in pain intensity than the guideline group, but this difference was absent after 52 weeks. We finally conclude that an intensive group training protocol was not more effective than usual physiotherapy for chronic low back pain.

Non-operative management of arterial liver hemorrhages

Energy Technology Data Exchange (ETDEWEB)

Goerich, J.; Rilinger, N.; Vogel, J.; Sokiranski, R.; Brambs, H.J. [Dept. of Radiology, University of Ulm (Germany); Brado, M. [Dept. of Radiology, Univ. of Heidelberg (Germany); Huppert, P. [Dept. of Radiology, Univ. of Tuebingen (Germany); Siech, M.; Ganzauge, F.; Beger, H.G. [Dept. of Surgery, Univ. of Ulm (Germany)

1999-02-01

A retrospective evaluation of embolotherapy in patients with arterial liver hemorrhages was carried out. Twenty-six patients, ranging in age from 10 days to 77 years with active arterial liver hemorrhages, underwent non-surgical embolotherapy. Bleeding was attributed to trauma (n = 21), tumor (n = 3), pancreatitis (n = 1), or unknown cause (n = 1). Twenty-nine embolizations were performed via a transfemoral (n = 26) or biliary (n = 2) approach. One bare Wallstent was placed into the common hepatic artery via to an axillary route to cover a false aneurysm due to pancreatitis. Treatment was controlled in 4 patients by cholangioscopy (n = 2) or by intravascular ultrasound (n = 2). Prior surgery had failed in 3 patients. Intervention controlled the hemorrhage in 24 of 26 (92 %) patients within 24 h. Embolotherapy failed in 1 patient with pancreatic carcinoma and occlusion of the portal vein. In 1 patient with an aneurysm of the hepatic artery treated by Wallstent insertion, total occlusion was not achieved in the following days, as demonstrated by CT and angiography. However, colour Doppler flow examination showed no flow in the aneurysm 6 months later. Complications were one liver abscess, treated successfully by percutaneous drainage for 10 days, and one gallbladder necrosis after superselective embolization of the cystic artery. Embolization is a effective tool with a low complication rate in the treatment of liver artery hemorrhage, even in patients in whom surgery has failed. (orig.) (orig.) With 2 figs., 26 refs.

Dexamethasone and supportive care with or without whole brain radiotherapy in treating patients with non-small cell lung cancer with brain metastases unsuitable for resection or stereotactic radiotherapy (QUARTZ): results from a phase 3, non-inferiority, randomised trial

OpenAIRE

Mulvenna, Paula; Nankivell, Matthew; Barton, Rachael; Faivre-Finn, Corinne; Wilson, Paula; McColl, Elaine; Moore, Barbara; Brisbane, Iona; Ardron, David; Holt, Tanya; Morgan, Sally; Lee, Caroline; Waite, Kathryn; Bayman, Neil; Pugh, Cheryl

2016-01-01

Summary Background Whole brain radiotherapy (WBRT) and dexamethasone are widely used to treat brain metastases from non-small cell lung cancer (NSCLC), although there have been no randomised clinical trials showing that WBRT improves either quality of life or overall survival. Even after treatment with WBRT, the prognosis of this patient group is poor. We aimed to establish whether WBRT could be omitted without a significant effect on survival or quality of life. Methods The Quality of Life a...

Impulsive and non-impulsive suicide attempts in patients treated for alcohol dependence.

Science.gov (United States)

Wojnar, Marcin; Ilgen, Mark A; Czyz, Ewa; Strobbe, Stephen; Klimkiewicz, Anna; Jakubczyk, Andrzej; Glass, Jennifer; Brower, Kirk J

2009-05-01

Suicidal behavior has been recognized as an increasing problem among alcohol-dependent subjects. The aim of the study was to identify correlates of impulsive and non-impulsive suicide attempts among a treated population of alcohol-dependent patients. A total of 154 patients with alcohol dependence consecutively admitted for addiction treatment participated in the study. Suicidal behavior was assessed together with severity of alcohol dependence, childhood abuse, impulsivity, and family history. A stop-signal procedure was used as a behavioral measure of impulsivity. Lifetime suicide attempts were reported by 43% of patients in alcohol treatment; of which 62% were impulsive. Compared to patients without a suicide attempt, those with a non-impulsive attempt were more likely to have a history of sexual abuse (OR=7.17), a family history of suicide (OR=4.09), and higher scores on a personality measure of impulsiveness (OR=2.27). The only significant factor that distinguished patients with impulsive suicide attempts from patients without a suicide attempt and from patients with a non-impulsive suicide attempt was a higher level of behavioral impulsivity (OR=1.84-2.42). Retrospective self-report of suicide attempts and family history. Lack of diagnostic measure.

Risk and benefit of dual antiplatelet treatment among non-revascularized myocardial infarction patients in different age groups.

Science.gov (United States)

Juul, Nikolai; Gislason, Gunnar; Olesen, Jonas Bjerring; Lamberts, Morten; Hansen, Morten Lock; Karasoy, Deniz; Christiansen, Christine Benn; Torp-Pedersen, Christian; Sorensen, Rikke

2017-09-01

Dual anti-platelet treatment with clopidogrel and aspirin is indicated for most patients after myocardial infarction. We examined the risk/benefit relationship of dual anti-platelet treatment according to age in a nationwide cohort of 30,532 myocardial infarction patients without revascularization. Patients admitted with first-time myocardial infarction in 2002-2010, not undergoing revascularization, were identified from nationwide Danish registers. Dual anti-platelet treatment use was assessed by claimed prescriptions. Stratified into age groups, risk of bleeding, all-cause mortality and a combined endpoint of cardiovascular death, recurrent myocardial infarction and ischaemic stroke was analysed by Cox proportional-hazard models and tested in a propensity-score matched population. A total of 21,302 users and 9230 non-users of dual anti-platelet treatment were included (mean age 67.02 (±13.8) years and 64.7% males). Use of dual anti-platelet treatment decreased with age: 80% (79 years). We found a reduced risk of cardiovascular death, recurrent myocardial infarction and ischaemic stroke in users 79 years (HR=0.92; 95% CI 0.84-1.01, NS). Risk of bleeding increased with dual anti-platelet treatment use in patients aged 79 years (HR=1.46; 95% CI 1.22-1.74). Similar tendencies in all four age groups were found in the propensity-matched population. Dual anti-platelet treatment use was less likely among elderly patients although similar effects regarding both risk and benefit were found in all age groups. Increased focus on initiating dual anti-platelet treatment in elderly, non-invasively treated myocardial infarction patients is warranted.

A third generation regimen VACOP-B with or without adjuvant radiotherapy for aggressive localized non-Hodgkin's lymphoma: report from the Italian Non-Hodgkin's Lymphoma Co-operative Study Group

Directory of Open Access Journals (Sweden)

G. Santini

2004-05-01

Full Text Available The objective of this multicenter prospective study was to determine the clinical efficacy and toxicity of a polychemotherapeutic third generation regimen, VACOP-B, with or without radiotherapy as front-line therapy in aggressive localized non-Hodgkin's lymphoma. Ninety-three adult patients (47 males and 46 females, median age 45 years with aggressive localized non-Hodgkin's lymphoma, 43 in stage I and 50 in stage II (non-bulky, were included in the study. Stage I patients received VACOP-B for 6 weeks plus involved field radiotherapy and stage II patients received 12 weeks VACOP-B plus involved field radiotherapy on residual masses. Eighty-six (92.5% achieved complete remission and 4 (4.3% partial remission. Three patients (3.2% were primarily resistant. Ten-year probability of survival, progression-free survival and disease-free survival were 87.3, 79.9 and 83.9%, respectively. Eighty-four patients are surviving at a median observation time of 57 months (range: 6-126. Statistical analysis showed no difference between stages I and II in terms of response, ten-year probability of survival, progression-free survival or disease-free survival. Side effects and toxicity were negligible and were similar in the two patient groups. The results of this prospective study suggest that 6 weeks of VACOP-B treatment plus radiotherapy may be the therapy of choice in stage I aggressive non-Hodgkin's lymphoma. Twelve weeks of VACOP-B treatment with or without radiotherapy was shown to be effective and feasible for stage II. These observations need to be confirmed by a phase III study comparing first and third generation protocols in stage I-II aggressive non-Hodgkin's lymphoma.

A model-based approach to operational event groups ranking

Energy Technology Data Exchange (ETDEWEB)

Simic, Zdenko [European Commission Joint Research Centre, Petten (Netherlands). Inst. for Energy and Transport; Maqua, Michael [Gesellschaft fuer Anlagen- und Reaktorsicherheit mbH (GRS), Koeln (Germany); Wattrelos, Didier [Institut de Radioprotection et de Surete Nucleaire (IRSN), Fontenay-aux-Roses (France)

2014-04-15

The operational experience (OE) feedback provides improvements in all industrial activities. Identification of the most important and valuable groups of events within accumulated experience is important in order to focus on a detailed investigation of events. The paper describes the new ranking method and compares it with three others. Methods have been described and applied to OE events utilised by nuclear power plants in France and Germany for twenty years. The results show that different ranking methods only roughly agree on which of the event groups are the most important ones. In the new ranking method the analytical hierarchy process is applied in order to assure consistent and comprehensive weighting determination for ranking indexes. The proposed method allows a transparent and flexible event groups ranking and identification of the most important OE for further more detailed investigation in order to complete the feedback. (orig.)

FIRMS’ TRANSNATIONALIZATION. EVOLUTION OF MULTINATIONAL GROUPS OPERATING IN ROMANIA

Directory of Open Access Journals (Sweden)

Carmen NISTOR

2014-11-01

Full Text Available International business development is a complex phenomenon, characterized by a particularly dynamic due both to external and internal factors of the company and the need to foreshadow future directions in the development of the economic, social, political framework. Taking into consideration the ways that a company can expand, this article aims to analyse the evolution of multinational corporations operating in Romania in 2007-2012. Using data provided by The National Institute of Statistics (NIS, we focus on the multinationals groups that entered Romanian market in the period mentioned above. In this regard, we compared the multinational groups with the national ones, identifying the concentration of foreign capital by country. The results show that although has been recorded a significant variation of multinational groups in Romania, especially during the financial crisis period, the companies from Deutschland occupy first place by number of employees.

Operative arthroscopy.

Science.gov (United States)

Guhl, J F

1979-01-01

In a period of 20 months, over 200 patients (age ranged from high school students to middle-aged persons) with knee injuries were treated by operative arthroscopy. The majority of the injuries were incurred while the patients had been participating in athletic events, either competitive or recreational. Operative arthroscopy offers the advantage of shortened hospital stay, rapid rehabilitation, lack of disfiguring scar, and reduced costs. Patients are followed yearly after the first postoperative year. Improved long-term results from diagnostic and operative arthroscopy, as compared to conventional surgical procedures, are expected. The proof of those expectations will be determined in the next several years as this group of patients requiring partial meniscectomies or procedures for pathologic and degenerative conditions is reevaluated.

Spectral multipliers on spaces of distributions associated with non-negative self-adjoint operators

DEFF Research Database (Denmark)

Georgiadis, Athanasios; Nielsen, Morten

2018-01-01

and Triebel–Lizorkin spaces with full range of indices is established too. As an application, we obtain equivalent norm characterizations for the spaces mentioned above. Non-classical spaces as well as Lebesgue, Hardy, (generalized) Sobolev and Lipschitz spaces are also covered by our approach.......We consider spaces of homogeneous type associated with a non-negative self-adjoint operator whose heat kernel satisfies certain upper Gaussian bounds. Spectral multipliers are introduced and studied on distributions associated with this operator. The boundedness of spectral multipliers on Besov...

Analysis of the TREAT LEU Conceptual Design

Energy Technology Data Exchange (ETDEWEB)

Connaway, H. M. [Argonne National Lab. (ANL), Argonne, IL (United States); Kontogeorgakos, D. C. [Argonne National Lab. (ANL), Argonne, IL (United States); Papadias, D. D. [Argonne National Lab. (ANL), Argonne, IL (United States); Brunett, A. J. [Argonne National Lab. (ANL), Argonne, IL (United States); Mo, K. [Argonne National Lab. (ANL), Argonne, IL (United States); Strons, P. S. [Argonne National Lab. (ANL), Argonne, IL (United States); Fei, T. [Argonne National Lab. (ANL), Argonne, IL (United States); Wright, A. E. [Argonne National Lab. (ANL), Argonne, IL (United States)

2016-03-01

Analyses were performed to evaluate the performance of the low enriched uranium (LEU) conceptual design fuel for the conversion of the Transient Reactor Test Facility (TREAT) from its current highly enriched uranium (HEU) fuel. TREAT is an experimental nuclear reactor designed to produce high neutron flux transients for the testing of reactor fuels and other materials. TREAT is currently in non-operational standby, but is being restarted under the U.S. Department of Energy’s Resumption of Transient Testing Program. The conversion of TREAT is being pursued in keeping with the mission of the Department of Energy National Nuclear Security Administration’s Material Management and Minimization (M3) Reactor Conversion Program. The focus of this study was to demonstrate that the converted LEU core is capable of maintaining the performance of the existing HEU core, while continuing to operate safely. Neutronic and thermal hydraulic simulations have been performed to evaluate the performance of the LEU conceptual-design core under both steady-state and transient conditions, for both normal operation and reactivity insertion accident scenarios. In addition, ancillary safety analyses which were performed for previous LEU design concepts have been reviewed and updated as-needed, in order to evaluate if the converted LEU core will function safely with all existing facility systems. Simulations were also performed to evaluate the detailed behavior of the UO₂-graphite fuel, to support future fuel manufacturing decisions regarding particle size specifications. The results of these analyses will be used in conjunction with work being performed at Idaho National Laboratory and Los Alamos National Laboratory, in order to develop the Conceptual Design Report project deliverable.

OPERATIVE GROUP: EDUCATIONAL PRACTICE AS AN EXPRESSION FOR SELF-CARE IN DIABETES MELLITUS TYPE 2

Directory of Open Access Journals (Sweden)

Mariana Almeida Maia

2013-12-01

Full Text Available The goal is to understand the views of users with type 2 diabetes about their participation in the operating groups and the impact of self-care practices. This is a qualitative descriptive- exploratory held in three basic health units of the sanitary district east of Belo Horizonte and involved the participation of 18 users in 2011. The speeches of the users were analyzed based on content analysis, identifying the categories: exchange of experience, education for self- care, assessment of user participation in the operative groups, Feelings and links between professionals and users. It was noted that the operational groups provided the construction of knowledge through listening, reflection and questioning of reality where the user identified the importance of knowledge about diet, physical activity and treatment. We found that health actions implemented through the operational groups encourage users to think about your lifestyle, characterized as a tool in health education from the perspective of promotion, prevention and control.

Probabilistic Linguistic Power Aggregation Operators for Multi-Criteria Group Decision Making

Directory of Open Access Journals (Sweden)

Agbodah Kobina

2017-12-01

Full Text Available As an effective aggregation tool, power average (PA allows the input arguments being aggregated to support and reinforce each other, which provides more versatility in the information aggregation process. Under the probabilistic linguistic term environment, we deeply investigate the new power aggregation (PA operators for fusing the probabilistic linguistic term sets (PLTSs. In this paper, we firstly develop the probabilistic linguistic power average (PLPA, the weighted probabilistic linguistic power average (WPLPA operators, the probabilistic linguistic power geometric (PLPG and the weighted probabilistic linguistic power geometric (WPLPG operators. At the same time, we carefully analyze the properties of these new aggregation operators. With the aid of the WPLPA and WPLPG operators, we further design the approaches for the application of multi-criteria group decision-making (MCGDM with PLTSs. Finally, we use an illustrated example to expound our proposed methods and verify their performances.

q-deformed differential operator algebra and new braid group representation

International Nuclear Information System (INIS)

Wang Luyu; Dai Jianghui; Zhang Jun

1991-01-01

It is proved that the q-deformed differential operator algebra introduced is consistent with quantum hyperplane described by Wess and Zumino. At the same time, a new braid group representation associated with sl q (2) is obtained by adding the terms of weight conservation to the standard universal R-matrix. (author). 10 refs

On generator systems for non-torsion Abelian groups of infinite free rank

International Nuclear Information System (INIS)

Lebedenko, V.M.

1977-01-01

The paper is further advance in solution of the Dlab problem related to the systems of generators of Abelian groups. Some existence criteria for hereditarily strongly reducible systems of generators of Abelian groups are presented. On this basis the distribution of non-torsion groups of infinite free rank on Dlab's classes is obtained

Perturbative expansion of Chern-Simons theory with non-compact gauge group

International Nuclear Information System (INIS)

Bar-Natan, D.; Witten, E.

1991-01-01

Naive imitation of the usual formulas for compact gauge group in quantizing three dimensional Chern-Simons gauge theory with non-compact gauge group leads to formulas that are wrong or unilluminating. In this paper, an appropriate modification is described, which puts the perturbative expansion in a standard manifestly 'unitary' format. The one loop contributions (which differ from naive extrapolation from the case of compact gauge group) are computed, and their topological invariance is verified. (orig.)

Treating depressive symptoms in psychosis : A Network Meta-Analysis on the Effects of Non-Verbal Therapies

NARCIS (Netherlands)

Steenhuis, L. A.; Nauta, M. H.; Bockting, C. L. H.; Pijnenborg, G. H. M.

2015-01-01

AIMS: The aim of this study was to examine whether non-verbal therapies are effective in treating depressive symptoms in psychotic disorders. MATERIAL AND METHODS: A systematic literature search was performed in PubMed, Psychinfo, Picarta, Embase and ISI Web of Science, up to January 2015.

Treating depressive symptoms in psychosis : A network meta-analysis on the effects of non-verbal therapies

NARCIS (Netherlands)

Steenhuis, Laura A.; Nauta, Maaike H.; Bocking, Claudi L.H.; Pijnenborg, Gerdina H.M.

2015-01-01

AIMS: The aim of this study was to examine whether non-verbal therapies are effective in treating depressive symptoms in psychotic disorders. MATERIAL AND METHODS: A systematic literature search was performed in PubMed, Psychinfo, Picarta, Embase and ISI Web of Science, up to January 2015.

Prospective Trial of Stereotactic Body Radiation Therapy for Both Operable and Inoperable T1N0M0 Non-Small Cell Lung Cancer: Japan Clinical Oncology Group Study JCOG0403

Energy Technology Data Exchange (ETDEWEB)

Nagata, Yasushi, E-mail: nagat@hiroshima-u.ac.jp [Department of Radiation Oncology, Hiroshima University, Hiroshima (Japan); Hiraoka, Masahiro [Department of Radiation Oncology and Image-Applied Therapy, Kyoto University, Kyoto (Japan); Shibata, Taro [Japan Clinical Oncology Group Data Center, Center for Research Administration and Support, National Cancer Center, Tokyo (Japan); Onishi, Hiroshi [Department of Radiology, University of Yamanashi, Chuo (Japan); Kokubo, Masaki [Department of Image-Based Medicine, Institute of Biomedical Research and Innovation, Kobe (Japan); Karasawa, Katsuyuki [Department of Radiation Oncology, Tokyo Metropolitan Komagome Hospital, Tokyo (Japan); Shioyama, Yoshiyuki [Department of Clinical Radiology, Kyushu University, Fukuoka (Japan); Onimaru, Rikiya [Department of Radiology, Hokkaido University, Sapporo (Japan); Kozuka, Takuyo [Department of Radiation Oncology, The Cancer Institute Hospital, Tokyo (Japan); Kunieda, Etsuo [Department of Radiation Oncology, Keio University, Tokyo (Japan); Saito, Tsutomu [Department of Radiology, Nihon University Itabashi Hospital, Tokyo (Japan); Nakagawa, Keiichi [Department of Radiology, The University of Tokyo Hospital, Tokyo (Japan); Hareyama, Masato [Department of Radiology, Sapporo Medical University, Sapporo (Japan); Takai, Yoshihiro [Department of Radiation Oncology, Tohoku University, Sendai (Japan); Hayakawa, Kazushige [Department of Radiology and Radiation Oncology, Kitasato University, Sagamihara (Japan); Mitsuhashi, Norio [Department of Radiation Oncology, Tokyo Women' s Medical University, Tokyo (Japan); Ishikura, Satoshi [Department of Radiology, Koshigaya Municipal Hospital, Koshigaya (Japan)

2015-12-01

Purpose: To evaluate, in Japan Clinical Oncology Group study 0403, the safety and efficacy of stereotactic body radiation therapy (SBRT) in patients with T1N0M0 non-small cell lung cancer (NSCLC). Methods and Materials: Eligibility criteria included histologically or cytologically proven NSCLC, clinical T1N0M0. Prescribed dose was 48 Gy at the isocenter in 4 fractions. The primary endpoint was the percent (%) 3-year overall survival. The threshold % 3-year survival to be rejected was set at 35% for inoperable patients, whereas the expected % 3-year survival was 80% for operable patients. Results: Between July 2004 and November 2008, 169 patients from 15 institutions were registered. One hundred inoperable and 64 operable patients (total 164) were eligible. Patients' characteristics were 122 male, 47 female; median age 78 years (range, 50-91 years); adenocarcinomas, 90; squamous cell carcinomas, 61; others, 18. Of the 100 inoperable patients, the % 3-year OS was 59.9% (95% confidence interval 49.6%-68.8%). Grade 3 and 4 toxicities were observed in 10 and 2 patients, respectively. No grade 5 toxicity was observed. Of the 64 operable patients, the % 3-year OS was 76.5% (95% confidence interval 64.0%-85.1%). Grade 3 toxicities were observed in 5 patients. No grade 4 and 5 toxicities were observed. Conclusions: Stereotactic body radiation therapy for stage I NSCLC is effective, with low incidences of severe toxicity. This treatment can be considered a standard treatment for inoperable stage I NSCLC. This treatment is promising as an alternative to surgery for operable stage I NSCLC.

Prospective Trial of Stereotactic Body Radiation Therapy for Both Operable and Inoperable T1N0M0 Non-Small Cell Lung Cancer: Japan Clinical Oncology Group Study JCOG0403

International Nuclear Information System (INIS)

Nagata, Yasushi; Hiraoka, Masahiro; Shibata, Taro; Onishi, Hiroshi; Kokubo, Masaki; Karasawa, Katsuyuki; Shioyama, Yoshiyuki; Onimaru, Rikiya; Kozuka, Takuyo; Kunieda, Etsuo; Saito, Tsutomu; Nakagawa, Keiichi; Hareyama, Masato; Takai, Yoshihiro; Hayakawa, Kazushige; Mitsuhashi, Norio; Ishikura, Satoshi

2015-01-01

Purpose: To evaluate, in Japan Clinical Oncology Group study 0403, the safety and efficacy of stereotactic body radiation therapy (SBRT) in patients with T1N0M0 non-small cell lung cancer (NSCLC). Methods and Materials: Eligibility criteria included histologically or cytologically proven NSCLC, clinical T1N0M0. Prescribed dose was 48 Gy at the isocenter in 4 fractions. The primary endpoint was the percent (%) 3-year overall survival. The threshold % 3-year survival to be rejected was set at 35% for inoperable patients, whereas the expected % 3-year survival was 80% for operable patients. Results: Between July 2004 and November 2008, 169 patients from 15 institutions were registered. One hundred inoperable and 64 operable patients (total 164) were eligible. Patients' characteristics were 122 male, 47 female; median age 78 years (range, 50-91 years); adenocarcinomas, 90; squamous cell carcinomas, 61; others, 18. Of the 100 inoperable patients, the % 3-year OS was 59.9% (95% confidence interval 49.6%-68.8%). Grade 3 and 4 toxicities were observed in 10 and 2 patients, respectively. No grade 5 toxicity was observed. Of the 64 operable patients, the % 3-year OS was 76.5% (95% confidence interval 64.0%-85.1%). Grade 3 toxicities were observed in 5 patients. No grade 4 and 5 toxicities were observed. Conclusions: Stereotactic body radiation therapy for stage I NSCLC is effective, with low incidences of severe toxicity. This treatment can be considered a standard treatment for inoperable stage I NSCLC. This treatment is promising as an alternative to surgery for operable stage I NSCLC.

Non-Hermitian Operator Modelling of Basic Cancer Cell Dynamics

Science.gov (United States)

Bagarello, Fabio; Gargano, Francesco

2018-04-01

We propose a dynamical system of tumor cells proliferation based on operatorial methods. The approach we propose is quantum-like: we use ladder and number operators to describe healthy and tumor cells birth and death, and the evolution is ruled by a non-hermitian Hamiltonian which includes, in a non reversible way, the basic biological mechanisms we consider for the system. We show that this approach is rather efficient in describing some processes of the cells. We further add some medical treatment, described by adding a suitable term in the Hamiltonian, which controls and limits the growth of tumor cells, and we propose an optimal approach to stop, and reverse, this growth.

Optimal recovery of linear operators in non-Euclidean metrics

Energy Technology Data Exchange (ETDEWEB)

Osipenko, K Yu [Moscow State Aviation Technological University, Moscow (Russian Federation)

2014-10-31

The paper looks at problems concerning the recovery of operators from noisy information in non-Euclidean metrics. A number of general theorems are proved and applied to recovery problems for functions and their derivatives from the noisy Fourier transform. In some cases, a family of optimal methods is found, from which the methods requiring the least amount of original information are singled out. Bibliography: 25 titles.

Impact of low skeletal muscle mass on non-lung cancer mortality after stereotactic body radiotherapy for patients with stage I non-small cell lung cancer.

Science.gov (United States)

Matsuo, Yukinori; Mitsuyoshi, Takamasa; Shintani, Takashi; Iizuka, Yusuke; Mizowaki, Takashi

2018-05-17

The purpose of the present study was to retrospectively evaluate impact of pre-treatment skeletal muscle mass (SMM) on overall survival and non-lung cancer mortality after stereotactic body radiotherapy (SBRT) for patients with stage I non-small cell lung cancer (NSCLC). One-hundred and eighty-six patients whose abdominal CT before the treatment was available were enrolled into this study. The patients were divided into two groups of SMM according to gender-specific thresholds for unilateral psoas area. Operability was judged by the treating physician or thoracic surgeon after discussion in a multi-disciplinary tumor board. Patients with low SMM tended to be elderly and underweight in body mass index compared with the high SMM. Overall survival in patients with the low SMM tended to be worse than that in the high SMM (41.1% and 55.9% at 5 years, P = 0.115). Cumulative incidence of non-lung cancer death was significantly worse in the low SMM (31.3% at 5 years compared with 9.7% in the high SMM, P = 0.006). Multivariate analysis identified SMM and operability as significant factors for non-lung cancer mortality. Impact of SMM on lung cancer death was not significant. No difference in rate of severe treatment-related toxicity was observed between the SMM groups. Low SMM is a significant risk factor for non-lung cancer death, which might lead to worse overall survival, after SBRT for stage I NSCLC. However, the low SMM does not increase lung cancer death or severe treatment-related toxicity. Copyright © 2018 Elsevier Inc. All rights reserved.

Effects of self-monitoring of glucose on distress and self-efficacy in people with non-insulin-treated Type 2 diabetes: a randomized controlled trial

NARCIS (Netherlands)

Malanda, U. L.; Bot, S. D. M.; Kostense, P. J.; Snoek, F. J.; Dekker, J. M.; Nijpels, G.

2016-01-01

To investigate the effects of self-monitoring of glucose in blood or urine, on diabetes-specific distress and self-efficacy, compared with usual care in people with non-insulin-treated Type 2 diabetes mellitus. One hundred and eighty-one participants with non-insulin-treated Type 2 diabetes mellitus

Fast and local non-linear evolution of steep wave-groups on deep water: A comparison of approximate models to fully non-linear simulations

International Nuclear Information System (INIS)

Adcock, T. A. A.; Taylor, P. H.

2016-01-01

The non-linear Schrödinger equation and its higher order extensions are routinely used for analysis of extreme ocean waves. This paper compares the evolution of individual wave-packets modelled using non-linear Schrödinger type equations with packets modelled using fully non-linear potential flow models. The modified non-linear Schrödinger Equation accurately models the relatively large scale non-linear changes to the shape of wave-groups, with a dramatic contraction of the group along the mean propagation direction and a corresponding extension of the width of the wave-crests. In addition, as extreme wave form, there is a local non-linear contraction of the wave-group around the crest which leads to a localised broadening of the wave spectrum which the bandwidth limited non-linear Schrödinger Equations struggle to capture. This limitation occurs for waves of moderate steepness and a narrow underlying spectrum

Winter School on Operator Spaces, Noncommutative Probability and Quantum Groups

CERN Document Server

2017-01-01

Providing an introduction to current research topics in functional analysis and its applications to quantum physics, this book presents three lectures surveying recent progress and open problems.  A special focus is given to the role of symmetry in non-commutative probability, in the theory of quantum groups, and in quantum physics. The first lecture presents the close connection between distributional symmetries and independence properties. The second introduces many structures (graphs, C*-algebras, discrete groups) whose quantum symmetries are much richer than their classical symmetry groups, and describes the associated quantum symmetry groups. The last lecture shows how functional analytic and geometric ideas can be used to detect and to quantify entanglement in high dimensions.  The book will allow graduate students and young researchers to gain a better understanding of free probability, the theory of compact quantum groups, and applications of the theory of Banach spaces to quantum information. The l...

Effects of edaravone, the free radical scavenger, on outcomes in acute cerebral infarction patients treated with ultra-early thrombolysis of recombinant tissue plasminogen activator.

Science.gov (United States)

Lee, Xian-Ru; Xiang, Gui-Ling

2018-04-01

Edaravone, a free radical scavenger, alleviates blood-brain barrier disruption in conjunction with suppression of the inflammatory reaction in acute cerebral infarction. Thrombolysis with recombinant tissue plasminogen activator (rtPA) is an established therapy for acute cerebral infarction patients. The purpose of this study was to assess the effects of edaravone on outcomes in acute cerebral infarction patients treated with ultra-early thrombolysis of iv-rt-PA. We conducted a retrospective cohort study using the database of Ningbo First Hospital. We identified patients who were admitted with a primary diagnosis of acute cerebral infarction and treated with intravenous rtPA(iv-rtPA) within 3 h of symptom onset from March 1st in 2014 to October 31st in 2016.Thenceforth,the patients were divided into 2 groups by treatment with(edaravone group) or without edaravone(non-edaravone group). Glasgow Coma Scale (GCS) scores and mRS score at admission were used. Clinical background, risk factors for acute cerebral infarction hemorrhagic transformation, 7-day mortality, recanalization rate, bleeding complications and blood rheology indexes were collected. We also collected the following factors: National Institutes of Health Stroke Scale scores, barthel index. 136 patients treated without edaravone during hospitalization were selected in non-edaravone group while edaravone group included 132 patients treated with edaravone during hospitalization. The patient baseline distributions were well balanced between non-edaravone group and edaravone group. The rate of hemorrhagic transformation in non-edaravone group was higher than that in edaravone group (P ＜ 0.05). The NIHSS scores 7 days and 14 days after symptom onset were higher in non-edaravone group than in edaravone group (both P ＜ 0.05). Edaravone group showed a higher recanalization rate and a lower bleeding complications rate at discharge than the non-edaravone group (both P ＜ 0.05). The differences of

Heat-treated (in single aliquot or batch) colostrum outperforms non-heat-treated colostrum in terms of quality and transfer of immunoglobulin G in neonatal Jersey calves.

Science.gov (United States)

Kryzer, A A; Godden, S M; Schell, R

2015-03-01

The objective of this randomized clinical trial was to describe the effect on colostrum characteristics and passive transfer of IgG in neonatal calves when using the Perfect Udder colostrum management system (single-aliquot treatment; Dairy Tech Inc., Greeley, CO) compared with a negative control (fresh refrigerated or fresh frozen colostrum) and a positive control (batch heat-treated colostrum). First-milking Jersey colostrum was pooled to achieve 31 unique batches with a minimum of 22.8 L per batch. The batch was then divided into 4 with 3.8 L allocated to each treatment group: (1) heat-treated in Perfect Udder bag at 60°C for 60 min and then stored at -20°C (PU); (2) heat-treated in a batch pasteurizer (Dairy Tech Inc.) at 60°C for 60 min and then stored at -20°C in Perfect Udder bag (DTB; positive control); (3) fresh frozen colostrum stored at -20°C in Perfect Udder bag (FF; negative control); and (4) fresh refrigerated colostrum stored at 4°C in Perfect Udder bag (FR; negative control). Colostrum from all treatments was sampled for analysis of IgG concentration and bacterial culture immediately after batch assembly, after processing, and before feeding. Newborn Jersey calves were randomly assigned to be fed 3.8 L of colostrum from 1 of the 4 treatment groups. A prefeeding, 0-h blood sample was collected, calves were fed by esophageal tube within 2 h of birth, and then a 24-h postfeeding blood sample was collected. Paired serum samples from 0- and 24-h blood samples were analyzed for IgG concentration (mg/mL) using radial immunodiffusion analysis. The overall mean IgG concentration in colostrum was 77.9 g/L and was not affected by treatment. Prefeeding total plate counts (log10 cfu/mL) were significantly different for all 4 treatments and were lower for heat-treated colostrum (PU=4.23, DTB=3.63) compared with fresh colostrum (FF=5.68, FR=6.53). Total coliform counts (log10 cfu/mL) were also significantly different for all 4 treatments and were lower for

Method of independently operating a group of stages within a diffusion cascade

International Nuclear Information System (INIS)

Benedict, M.; Allen, J.F.; Levey, H.B.

1976-01-01

A method of operating a group of the diffusion stages of a productive diffusion cascade with counter-current flow is described. The group consists of a top and a bottom stage which isolates the group from the cascade. The diffused gas produced in the top stage is circulated to the feed of the bottom stage, while at the same time undiffused gas from the bottom stage is circulated to the feed of the top stage whereby major changes in inventory distribution within the group of stages are prevented

Matrix product operators, matrix product states, and ab initio density matrix renormalization group algorithms

Science.gov (United States)

Chan, Garnet Kin-Lic; Keselman, Anna; Nakatani, Naoki; Li, Zhendong; White, Steven R.

2016-07-01

Current descriptions of the ab initio density matrix renormalization group (DMRG) algorithm use two superficially different languages: an older language of the renormalization group and renormalized operators, and a more recent language of matrix product states and matrix product operators. The same algorithm can appear dramatically different when written in the two different vocabularies. In this work, we carefully describe the translation between the two languages in several contexts. First, we describe how to efficiently implement the ab initio DMRG sweep using a matrix product operator based code, and the equivalence to the original renormalized operator implementation. Next we describe how to implement the general matrix product operator/matrix product state algebra within a pure renormalized operator-based DMRG code. Finally, we discuss two improvements of the ab initio DMRG sweep algorithm motivated by matrix product operator language: Hamiltonian compression, and a sum over operators representation that allows for perfect computational parallelism. The connections and correspondences described here serve to link the future developments with the past and are important in the efficient implementation of continuing advances in ab initio DMRG and related algorithms.

Treating disorganized attachment in the Group Attachment-Based Intervention (GABI©): A case study.

Science.gov (United States)

Knafo, Hannah; Murphy, Anne; Steele, Howard; Steele, Miriam

2018-05-24

This paper describes the treatment of a mother and child who demonstrated disorganized attachment behaviors in their interactions with one another. The mother, who was diagnosed with Borderline Personality Disorder, felt incapable of managing her aggressive toddler and his emotional needs. The dyad was referred for therapy due to concerns about his developmental progress, evident delays having been mainly attributed to the problems observed within the parent-child relationship. The primary intervention applied to working with the dyad was the Group Attachment-Based Intervention (GABI©), developed by Anne Murphy in collaboration with Miriam Steele and Howard Steele. The mother also received individual psychotherapy as a supplement to the dyadic and group work of GABI©. The process and outcome of this comprehensive approach to treating a vulnerable dyad is explored in this case study. © 2018 Wiley Periodicals, Inc.

Clinical application of an improved utero-operator in the interventional treatment of infertility

International Nuclear Information System (INIS)

Huang Yaoming; Zhang Guangfu; Li Detai

2002-01-01

Objective: To evaluate the effectiveness of an improved utero-operator in the interventional treatment of tube obstruction infertility, and to make a comparison with other methods. Methods: One hundred cases of infertile women with tubal obstruction were divided into 3 groups and treated separately under TV fluoroscopy with 3 different methods and follow-up examination was made up to 24 months. Among the 100 cases, 60 cases were treated with improved utero-operator (109 tubes), 20 with Cook cupped coaxial catheter (36 tubes), and 20 with emulsoid double-cavity tube (20 tubes). Result: Among the improved utero-operator group, Cook cupped coaxial catheter group, and emulsoid double-cavity tube group, the successful rate of selective catheterization was 92.7%, 80.6% and 80.0%, respectively. The successful rate of recanalization was 72.3%, 72.4% and 71.4%, respectively. The pregnancy rate was 36.4%, 35.7% and 36.4%, respectively. Improved utero-operator has the highest successful rate in selective catheterization (x 2 = 4.275, P < 0.05). Conclusion: Improved utero-operator has a high successful rate of selective catheterization in selective salpingography and treatment of tube obstruction infertility, and it is an easy and stable method which spends less time and received less X-ray. It is an ideal treating method at the moment

Impact of sickle cell trait on the thrombotic risk associated with non-O blood groups in northern Nigeria.

Science.gov (United States)

Ahmed, Sagir G; Kagu, Modu B; Ibrahim, Umma A; Bukar, Audu A

2015-10-01

The non-O blood group is an established risk factor for deep vein thrombosis (DVT), while controversy surrounds the role of sickle cell trait (SCT) as a risk factor for DVT. We hypothesised that if SCT is a risk factor for DVT, individuals with non-O blood groups and SCT (Hb AS) would have a higher risk of DVT than their counterparts with non-O blood groups and normal haemoglobin phenotype (Hb AA). We retrospectively analysed the prevalence of SCT and non-O blood groups among 148 DVT patients with control subjects in order to determine the role of SCT as a risk factor for DVT and its impact on the risk of DVT among patients with non-O blood groups. In comparison with control subjects, DVT patients had significantly higher prevalences of SCT (35.1% vs 27.7%, p=0.04) and non-O blood groups (68.9% vs 45.9%, p=0.02). The odds ratios for DVT due to SCT, non-O blood groups with normal Hb phenotype (Hb AA) and non-O blood groups with SCT (Hb AS) were 1.3, 2.4 and 3.5, respectively. These results suggest that SCT by itself is a weak risk factor for DVT but it has the potential of escalating the DVT risk among patients with non-O blood groups. The combined effects of elevated clotting factors (non-O group effect) and increased clotting factor activation (SCT effect) were responsible for the escalated DVT risk among patients with co-inheritance of non-O blood groups and SCT. Co-inheritance of SCT and non-O blood group is, therefore, an important mixed risk factor for DVT. This should be taken into account when assessing DVT risk profiles of patients in Africa and other parts of the world where the SCT is prevalent.

Regulatory interventions necessitated by non-conservative operator decisions

International Nuclear Information System (INIS)

Ojha, D.; Chande, S.K.; Sharma, S.K.

2005-01-01

Presently, India has 15 nuclear power units in operation and 8 units under construction. Though the safety performance of the Nuclear Power Plants (NPPs) in India has been excellent, a few recent events indicate that conservative decision making process can possibly get affected by perceived production goals. In one of the events, a need for some maintenance work arose while reactor start-up was in progress. After it was realized that the maintenance would require considerable time, the proper course of action would have been to shutdown the reactor and add neutron poison to moderator to ensure sufficient sub criticality. This was not done, as it would have delayed the start up of the reactor on completion of maintenance. In another incident, an unintended slow increase in reactor power occurred due to the adjuster rods becoming inoperable on account of blowing-off of fuses in their power supply. Under this condition, the reactor should have been tripped which was not done. Further, the automatic addition of boron poison to the reactor was inhibited. Regulatory review showed that both the incidents were indicative of degradation in safety culture and reflected operator's overriding concern for keeping the units in operation. Appropriate corrective actions were taken to prevent recurrence of such events in the respective units as also in all other operating units of similar type. In the wake of improved production performance operators may develop a tendency to create new operational records and compete with other units. This aspect points out to a need for careful study of events to check the presence of any element of non-conservative decision-making and to identify leading indicators of degradation in safety performance. (author)

Perfect commuting-operator strategies for linear system games

Science.gov (United States)

Cleve, Richard; Liu, Li; Slofstra, William

2017-01-01

Linear system games are a generalization of Mermin's magic square game introduced by Cleve and Mittal. They show that perfect strategies for linear system games in the tensor-product model of entanglement correspond to finite-dimensional operator solutions of a certain set of non-commutative equations. We investigate linear system games in the commuting-operator model of entanglement, where Alice and Bob's measurement operators act on a joint Hilbert space, and Alice's operators must commute with Bob's operators. We show that perfect strategies in this model correspond to possibly infinite-dimensional operator solutions of the non-commutative equations. The proof is based around a finitely presented group associated with the linear system which arises from the non-commutative equations.

More complications in patients with septic shock treated with dextran compared with crystalloids

DEFF Research Database (Denmark)

Rasmussen, Anders Mølgaard; Peter Jakobsen, Rasmus; Strøm, Thomas

2015-01-01

INTRODUCTION: In recent years, the safety-profile of synthetic colloids has been questioned. The purpose of the present study was to elucidate the safety-profile of the colloid dextran-70 in relation to acute kidney injury (AKI) and death. METHODS: We conducted a retrospective, observational study...... of patients admitted to our intensive care unit with septic shock and treated with dextran-70 in the period from 1 January 2009 to 31 December 2009. The controls were included from 1 March 2012 to 28 February 2013 when dextran-70 was replaced with crystalloids. RESULTS: There were 91 patients in the dextran...... group and 150 patients in the non-dextran group. The urinary output was 17.93 ml/kg/24 h in the dextran group and 27.87 in the non-dextran group (p dextran group and in 23% in the non-dextran group (p

N-Springs pump and treat system optimization study

International Nuclear Information System (INIS)

1997-03-01

This letter report describes and presents the results of a system optimization study conducted to evaluate the N-Springs pump and treat system. The N-Springs pump and treat is designed to remove strontium-90 (90Sr) found in the groundwater in the 100-NR-2 Operable Unit near the Columbia River. The goal of the system optimization study was to assess and quantify what conditions and operating parameters could be employed to enhance the operating and cost effectiveness of the recently upgraded pump and treat system.This report provides the results of the system optimization study, reports the cost effectiveness of operating the pump and treat at various operating modes and 90Sr removal goals, and provides recommendations for operating the pump and treat

Relativistic dynamics, Green function and pseudodifferential operators

Energy Technology Data Exchange (ETDEWEB)

Cirilo-Lombardo, Diego Julio [National Institute of Plasma Physics (INFIP), Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Buenos Aires 1428 (Argentina); Bogoliubov Laboratory of Theoretical Physics, Joint Institute for Nuclear Research, 141980 Dubna (Russian Federation)

2016-06-15

The central role played by pseudodifferential operators in relativistic dynamics is known very well. In this work, operators like the Schrodinger one (e.g., square root) are treated from the point of view of the non-local pseudodifferential Green functions. Starting from the explicit construction of the Green (semigroup) theoretical kernel, a theorem linking the integrability conditions and their dependence on the spacetime dimensions is given. Relativistic wave equations with arbitrary spin and the causality problem are discussed with the algebraic interpretation of the radical operator and their relation with coherent and squeezed states. Also we perform by means of pure theoretical procedures (based in physical concepts and symmetry) the relativistic position operator which satisfies the conditions of integrability: it is a non-local, Lorentz invariant and does not have the same problems as the “local”position operator proposed by Newton and Wigner. Physical examples, as zitterbewegung and rogue waves, are presented and deeply analyzed in this theoretical framework.

Operating Experience Report: Counterfeit, Suspect and Fraudulent Items. Working Group on Operating Experience. Proceedings and Analysis on an Item of Generic Interest

International Nuclear Information System (INIS)

2011-01-01

The NEA Committee on Nuclear Regulatory Activities (CNRA) believes that sharing operating experience from the national operating experience feedback programmes are a major element in the industry's and regulatory body's efforts to ensure the continued safe operation of nuclear facilities. Considering the importance of these issues, the Committee on the Safety of Nuclear Installations (CSNI) established a working group, PWG no.1 (Principle Working Group Number 1) to assess operating experience in the late 1970's, which was later renamed the Working Group on Operating Experience (WGOE). In 1978, the CSNI approved the establishment of a system to collect international operating experience data. The accident at Three Mile Island shortly after added impetus to this and led to the start of the Incident Reporting System (IRS). In 1983, the IRS database was moved to the International Agency for Atomic Energy (IAEA) to be operated as a joint database by IAEA and NEA for the benefit of all of the member countries of both organisations. In 2006, the WGOE was moved to be under the umbrella of the Committee on Nuclear Regulatory Activities (CNRA) in NEA. In 2009, the scope of the Incident Reporting System was expanded and re-named the International Reporting System for Operating Experience (although, the acronym remains the same). The purpose of WGOE is to facilitate the exchange of information, experience, and lessons learnt related to operating experience between member countries. The working group continues its mission to identify trending and issues that should be addressed in specialty areas of CNRA and CSNI working groups. The CSFI (Counterfeit, Suspect, and Fraudulent Items) issue was determined to be the Issue of Generic Interest at the April 2010 WGOE meeting. The Issue of Generic Interest is determined by the working group members for an in-depth discussion. They are often emerging issues in operating experience that a country or several countries would to the share

Cauchy problem for differential operators with double characteristics non-effectively hyperbolic characteristics

CERN Document Server

Nishitani, Tatsuo

2017-01-01

Combining geometrical and microlocal tools, this monograph gives detailed proofs of many well/ill-posed results related to the Cauchy problem for differential operators with non-effectively hyperbolic double characteristics. Previously scattered over numerous different publications, the results are presented from the viewpoint that the Hamilton map and the geometry of bicharacteristics completely characterizes the well/ill-posedness of the Cauchy problem. A doubly characteristic point of a differential operator P of order m (i.e. one where Pm = dPm = 0) is effectively hyperbolic if the Hamilton map FPm has real non-zero eigenvalues. When the characteristics are at most double and every double characteristic is effectively hyperbolic, the Cauchy problem for P can be solved for arbitrary lower order terms. If there is a non-effectively hyperbolic characteristic, solvability requires the subprincipal symbol of P to lie between − Pµj and P µj , where iµj are the positive imaginary eigenvalues of FPm ....

Coherent State Projection Operator Representation of Symplectic Transformations as a Loyal Representation of Symplectic Group

Science.gov (United States)

Fan, Hong-Yi; Chen, Jun-Hua

2002-08-01

We find that the coherent state projection operator representation of symplectic transformation constitutes a loyal group representation of symplectic group. The result of successively applying squeezing operators on number state can be easily derived. The project supported by National Natural Science Foundation of China under Grant No. 10575057 and the President Foundation of the Chinese Academy of Sciences

Results of Operative and Nonoperative Treatment of Rockwood Types III and V Acromioclavicular Joint Dislocation

Science.gov (United States)

Joukainen, Antti; Kröger, Heikki; Niemitukia, Lea; Mäkelä, E. Antero; Väätäinen, Urho

2014-01-01

Background: The optimal treatment of acute, complete dislocation of the acromioclavicular joint (ACJ) is still unresolved. Purpose: To determine the difference between operative and nonoperative treatment in acute Rockwood types III and V ACJ dislocation. Study Design: Randomized controlled trial; Level of evidence, 2. Methods: In the operative treatment group, the ACJ was reduced and fixed with 2 transarticular Kirschner wires and ACJ ligament suturing. The Kirschner wires were extracted after 6 weeks. Nonoperatively treated patients received a reduction splint for 4 weeks. At the 18- to 20-year follow-up, the Constant, University of California at Los Angeles Shoulder Rating Scale (UCLA), Larsen, and Simple Shoulder Test (SST) scores were obtained, and clinical and radiographic examinations of both shoulders were performed. Results: Twenty-five of 35 potential patients were examined at the 18- to 20-year follow-up. There were 11 patients with Rockwood type III and 14 with type V dislocations. Delayed surgical treatment for ACJ was used in 2 patients during follow-up: 1 in the operatively treated group and 1 in the nonoperatively treated group. Clinically, ACJs were statistically significantly less prominent or unstable in the operative group than in the nonoperative group (normal/prominent/unstable: 9/4/3 and 0/6/3, respectively; P = .02) and in the operative type III (P = .03) but not type V dislocation groups. In operatively and nonoperatively treated patients, the mean Constant scores were 83 and 85, UCLA scores 25 and 27, Larsen scores 11 and 11, and SST scores 11 and 12 at follow-up, respectively. There were no statistically significant differences in type III and type V dislocations. In the radiographic analysis, the ACJ was wider in the nonoperative than the operative group (8.3 vs 3.4 mm; P = .004), and in the type V dislocations (nonoperative vs operative: 8.5 vs 2.4 mm; P = .007). There was no statistically significant difference between study groups in

On Non-Frattini Chief Factors and Solvability of Finite Groups

Indian Academy of Sciences (India)

A subgroup of a group is said to be a semi C A P ∗ -subgroup of if there is a chief series 1 = G 0 < G 1 < ⋯ < G m = G of such that for every non-Frattini chief factor G i / G i − 1 , H either covers G i / G i − 1 or avoids G i / G i − 1 . In this paper, some sufficient conditions for a normal subgroup of a finite group to be ...

An introduction to quantum groups and non-commutative differential calculus

International Nuclear Information System (INIS)

Azcarraga, J.A. de; Rodenas, F.

1995-01-01

An introduction to quantum groups and quantum spaces is presented, and the non-commutative calculus on them is discussed. The case of q-Minkowski space is presented as an illustrative example. A set of useful expressions and formulae are collected in an appendix. 45 refs

Non-accretive Schrodinger operators and exponential decay of their eigenfunctions

Czech Academy of Sciences Publication Activity Database

Krejčiřík, David; Raymond, N.; Royer, J.; Siegl, Petr

2017-01-01

Roč. 221, č. 2 (2017), s. 779-802 ISSN 0021-2172 R&D Projects: GA ČR(CZ) GA14-06818S Institutional support: RVO:61389005 Keywords : non-self-adjoint electromagnetic Schrodinger operators * Dirichlet realisation * Agmon-type exponential decay Subject RIV: BA - General Mathematics OBOR OECD: Pure mathematics Impact factor: 0.796, year: 2016

Comparison of Short vs Long Anti-rotation in Treating Trochanteric Fractures

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Raval P

2016-03-01

Full Text Available Introduction: A comparative evaluation of the surgical treatment and outcome of patients with pertrochanteric fractures treated with short versus long proximal femoral nail antirotation. Materials and methods: A retrospective review was conducted of patients with pertrochanteric fractures treated between January 2011 and June 2012. In all 80 patients were enrolled in the study, of which 40 were treated with short PFNA and the remaining with long PFNA. Comparative analyses of demographic data, peri-operative outcome and complications were carried out. Results: There was no significant difference noted in the two groups with regards to Arbeitsgemeinschaft fur Osteosynthesefragen (AO fracture classification, time from injury to surgery, blood transfusion post surgery and hospital stay. The surgical duration for a short PFNA procedure was significantly less (58 minutes when compared to that of a long PFNA (87 minutes. Similarly intra-operative blood loss was significantly higher in the long PFNA group as compared to the short PFNA. Conclusions: A relatively quicker surgical time of just under an hour , lesser blood loss and better learning curve with trainee surgeons make short PFNA a better implant choice in the treatment of pertrochanteric fractures.

Non-safety piping operability review case study -- Today and tomorrow

International Nuclear Information System (INIS)

Flensburg, W.C.; Adams, T.M.

1995-01-01

During a 1993 Outage at the Perry Nuclear Power Station, a condition report was issued which identified potential intersystem loss of water between the Emergency Closed Cooling Water System and the Nuclear Closed Cooling Water System during a design basis event. The review of this condition report indicated that if a SSE (safe shutdown earthquake) event were to occur during a design basis event components important to plant safety could potentially be adversely affected if non-seismic/non-safety portions of the Nuclear Closed Cooling Water System could not maintain pressure boundary integrity as a result of the seismic loadings. Presented in this paper are steps, criteria, and methodology used to demonstrate the seismic acceptability of the affected portion of the Nuclear Closed Cooling Water System Piping. Also discussed are the potential benefits and applicability of a recently developed EPRI non-safety, non-seismic operability procedure. This discussion includes the potential cost savings which could have arisen from application of this recently developed procedure

Severity of infection and seasonal variation of non-typhoid Salmonelle occurence in humans

DEFF Research Database (Denmark)

Gradel, K.O.; Dethlefsen, Claus; Schønheyder, H.C.

2007-01-01

Non-typhoid Salmonella infections may present as severe gastroenteritis necessitatinghospitalization and some patients become septic with bacteraemia. We hypothesized that theseasonal variation of non-typhoid Salmonella occurrence in humans diminishes with increasedseverity of infection. We...... examined the seasonal variation of non-typhoid Salmonella infections inthree patient groups with differing severity of infection: outpatients treated for gastroenteritis(n=1490); in-patients treated for gastroenteritis (n=492); and in-patients treated for bacteraemia(n=113). The study was population......-based and included all non-typhoid Salmonella patients ina Danish county from 1994 to 2003. A periodic regression model was used to compute thepeak-to-trough ratio for the three patient groups. The peak-to-trough ratios were 4·3 [95%confidence interval (CI) 3·6–5.0] for outpatients with gastroenteritis, 3·2 (95% CI...

More complications in patients with septic shock treated with dextran compared with crystalloids.

Science.gov (United States)

Rasmussen, Anders Mølgaard; Jakobsen, Rasmus; Strøm, Thomas; Carlsson, Marcela; Dahler-Eriksen, Bjarne; Toft, Palle

2015-02-01

In recent years, the safety-profile of synthetic colloids has been questioned. The purpose of the present study was to elucidate the safety-profile of the colloid dextran-70 in relation to acute kidney injury (AKI) and death. We conducted a retrospective, observational study of patients admitted to our intensive care unit with septic shock and treated with dextran-70 in the period from 1 January 2009 to 31 December 2009. The controls were included from 1 March 2012 to 28 February 2013 when dextran-70 was replaced with crystalloids. There were 91 patients in the dextran group and 150 patients in the non-dextran group. The urinary output was 17.93 ml/kg/24 h in the dextran group and 27.87 in the non-dextran group (p dextran group and in 23% in the non-dextran group (p dextran group compared with 15% in the control group (p dextran group and 35% in the non-dextran group (p = 0.08). Patients in the dextran group had significantly more bleeding episodes, a higher need for CRRT and a lower urinary output than patients in the non-dextran group. Due to study design, it cannot be concluded that the use of dextran-70 is causally related to the development of AKI.

Diagonal form factors and hexagon form factorsII. Non-BPS light operator

International Nuclear Information System (INIS)

Jiang, Yunfeng

2017-01-01

We study the asymptotic volume dependence of the heavy-heavy-light three-point functions in the N=4 Super-Yang-Mills theory using the hexagon bootstrap approach, where the volume is the length of the heavy operator. We extend the analysis of our previous short letter http://dx.doi.org/10.1007/JHEP07(2016)120 to the general case where the heavy operators can be in any rank one sector and the light operator being a generic non-BPS operator. We prove the conjecture of Bajnok, Janik and Wereszczynski http://dx.doi.org/10.1007/JHEP09(2014)050 up to leading finite size corrections.

Diagonal form factors and hexagon form factorsII. Non-BPS light operator

Energy Technology Data Exchange (ETDEWEB)

Jiang, Yunfeng [Institut für Theoretische Physik, ETH Zürich,Wolfgang Pauli Strasse 27, CH-8093 Zürich (Switzerland)

2017-01-05

We study the asymptotic volume dependence of the heavy-heavy-light three-point functions in the N=4 Super-Yang-Mills theory using the hexagon bootstrap approach, where the volume is the length of the heavy operator. We extend the analysis of our previous short letter http://dx.doi.org/10.1007/JHEP07(2016)120 to the general case where the heavy operators can be in any rank one sector and the light operator being a generic non-BPS operator. We prove the conjecture of Bajnok, Janik and Wereszczynski http://dx.doi.org/10.1007/JHEP09(2014)050 up to leading finite size corrections.

Some applicationS of non-Hermitian operators in quantum mechanics and quantum field theory

International Nuclear Information System (INIS)

Recami, E.; Rodrigues, W.A. Jr.; Smrz, P.

1983-01-01

Due to the possibility of rephrasing it in terms of Lie-admissible algebras, some work done in the past in collaboration with A., Agodi, M., Baldo and V.S., Olkhovsky is here reported. Such work led to the introduction of non-Hermitian operators in (classical and relativistic) quantum theory. In particular: (i) the association of unstable states (decaying 'Resonances') with the eigenvectors of non-Hermitian hamiltonians; (ii) the problem of the four position operators for relativistic spin-zero particles are dealth with

Parallel point-multiplication architecture using combined group operations for high-speed cryptographic applications.

Directory of Open Access Journals (Sweden)

Md Selim Hossain

Full Text Available In this paper, we propose a novel parallel architecture for fast hardware implementation of elliptic curve point multiplication (ECPM, which is the key operation of an elliptic curve cryptography processor. The point multiplication over binary fields is synthesized on both FPGA and ASIC technology by designing fast elliptic curve group operations in Jacobian projective coordinates. A novel combined point doubling and point addition (PDPA architecture is proposed for group operations to achieve high speed and low hardware requirements for ECPM. It has been implemented over the binary field which is recommended by the National Institute of Standards and Technology (NIST. The proposed ECPM supports two Koblitz and random curves for the key sizes 233 and 163 bits. For group operations, a finite-field arithmetic operation, e.g. multiplication, is designed on a polynomial basis. The delay of a 233-bit point multiplication is only 3.05 and 3.56 μs, in a Xilinx Virtex-7 FPGA, for Koblitz and random curves, respectively, and 0.81 μs in an ASIC 65-nm technology, which are the fastest hardware implementation results reported in the literature to date. In addition, a 163-bit point multiplication is also implemented in FPGA and ASIC for fair comparison which takes around 0.33 and 0.46 μs, respectively. The area-time product of the proposed point multiplication is very low compared to similar designs. The performance ([Formula: see text] and Area × Time × Energy (ATE product of the proposed design are far better than the most significant studies found in the literature.

Identifying Differences Between Off-Highway Vehicle (OHV) and Non-OHV User Groups for Recreation Resource Planning

Science.gov (United States)

Kil, Namyun; Holland, Stephen M.; Stein, Taylor V.

2012-09-01

Off-highway vehicle (OHV) riding is among the fastest growing recreational activities in the United States. However, little research exists about the central components of outcomes-focused management (OFM) as it relates to motorized recreation. Utilizing a two-activity dichotomy, OHV and non-OHV centric user groups were compared on several key concepts associated with OFM, including desired experiences, perceived and desired recreation opportunity spectrum-type settings, and intentional behaviors (i.e., place-protective behavior, spending-time intentions) toward potential changes in settings. Results indicated that the two groups were different in terms of intensity and relative rankings of their perceived experiences and settings. Although both groups preferred social bonding, stress relief, nostalgia and learning experiences, the OHV user group ranked using equipment and achieving physical fitness experiences as more important than the non-OHV group. The non-OHV user group preferred enjoying nature and solitude/tranquility experiences more strongly than the OHV user group. Further analysis found that both groups perceived settings that they recreated in to be pristine and preferred such conditions, and both groups preferred moderate levels of rules and regulations. Finally, the OHV user group was more reactive to rules and regulations, while the non-OHV user group expressed stronger intentions to protect the environmental quality of recreation areas. The results suggest that planners and managers who understand OHV user's perceptions and behaviors could provide enhanced recreation opportunities potentially providing additional beneficial outcomes for motorized and non-motorized groups in spatially different zones. Additional implications for planners and managers and future studies are discussed.

Induced simplified neutrosophic correlated aggregation operators for multi-criteria group decision-making

Science.gov (United States)

Şahin, Rıdvan; Zhang, Hong-yu

2018-03-01

Induced Choquet integral is a powerful tool to deal with imprecise or uncertain nature. This study proposes a combination process of the induced Choquet integral and neutrosophic information. We first give the operational properties of simplified neutrosophic numbers (SNNs). Then, we develop some new information aggregation operators, including an induced simplified neutrosophic correlated averaging (I-SNCA) operator and an induced simplified neutrosophic correlated geometric (I-SNCG) operator. These operators not only consider the importance of elements or their ordered positions, but also take into account the interactions phenomena among decision criteria or their ordered positions under multiple decision-makers. Moreover, we present a detailed analysis of I-SNCA and I-SNCG operators, including the properties of idempotency, commutativity and monotonicity, and study the relationships among the proposed operators and existing simplified neutrosophic aggregation operators. In order to handle the multi-criteria group decision-making (MCGDM) situations where the weights of criteria and decision-makers usually correlative and the criterion values are considered as SNNs, an approach is established based on I-SNCA operator. Finally, a numerical example is presented to demonstrate the proposed approach and to verify its effectiveness and practicality.

[EFFECTIVENESS OF CLAVICULAR HOOK PLATE COMBINED WITH TRAPEZIUS MUSCLE FASCIA FOR RECONSTRUCTION OF ACROMIOCLAVICULAR AND CORACOCLAVICULAR LIGAMENTS TO TREAT COMPLETE ACROMIOCLAVICULAR JOINT DISLOCATION].

Science.gov (United States)

Wang, Chaoliang; Wang, Yingzhen; Zhu, Tao; Sun, Xuesheng; Lin, Chu; Gao, Bo; Li, Xinxia

2015-02-01

To explore the effectiveness of the clavicular hook plate combined with trapezius muscle fascia for reconstruction of acromioclavicular and coracoclavicular ligaments to treat acute complete acromioclavicular dislocations. Between January 2008 and April 2012, 66 patients with acromioclavicular dislocation were treated with the clavicular hook plate combined with trapezius muscle fascia for reconstruction of acromioclavicular and coracoclavicular ligaments in 32 cases (experimental group) and with the clavicular hook plate in 34 cases (control group). There was no significant difference in gender, age, injured side, the cause of injury, and the time from injury to operation between 2 groups (P > 0.05). Visual analogue scale (VAS), Constant shoulder scores, and coracoid clavi-cledistance (CC. Dist) were measured at preoperation and at 2 years after operation. Signal/noise quotiem (SNQ) was measured by MRI at 2 years after operation. The operation complications were observed. The patients of 2 groups obtained primary healing of incision. The morbidity of complication in experimental group (12.5%, 4/32) was significantly lower than that in control group (91.2%, 31/34) (Χ2 = 40.96, P = 0.00). All the cases were followed up 2.8 years on average (range, 2 to 4 years). VAS scores and CC.Dist significantly decreased at 2 years after operation when compared with preoperative values in the 2 groups (P acromioclavicular and coracoclavicular ligaments is successful in treating acute complete acromioclavicular dislocations, with the advantages of higher ligament healing, less complication, and early improvement of shoulder functions.

Thyroid cancer in toxic and non-toxic multinodular goiter

Directory of Open Access Journals (Sweden)

Cerci C

2007-01-01

Full Text Available Background : Many authors have claimed that hyperthyroidism protects against thyroid cancer and believed that the incidence of malignancy is lower in patients with toxic multinodular goiter (TMG than in those with non-toxic multinodular goiter. But in recent studies, it was reported that the incidence of malignancy with TMG is not as low as previously thought. Aim : To compare the thyroid cancer incidence in patients with toxic and non-toxic multinodular goiter. Settings and Design : Histology reports of patients treated surgically with a preoperative diagnosis of toxic and non-toxic multinodular goiter were reviewed to identify the thyroid cancer incidence. Patients having a history of neck irradiation or radioactive iodine therapy were excluded from the study. Materials and Methods : We reviewed 294 patients operated between 2001-2005 from toxic and non-toxic multinodular goiter. One hundred and twenty-four of them were toxic and 170 were non-toxic. Hyperthyroidism was diagnosed by elevated tri-iodothyroinine / thyroxine ratios and low thyroid-stimulating hormone with clinical signs and symptoms. All patients were evaluated with ultrasonography and scintigraphy and fine needle aspiration biopsy. Statistical Analysis Used : Significance of the various parameters was calculated by using ANOVA test. Results : The incidence of malignancy was 9% in the toxic and 10.58% in the non-toxic multinodular goiter group. Any significant difference in the incidence of cancer and tumor size between the two groups could not be detected. Conclusions : The incidence of malignancy in toxic multinodular goiter is not very low as thought earlier and is nearly the same in non-toxic multinodular goiter.

k-RAS mutations in non-small cell lung cancer patients treated with TKIs among smokers and non-smokers: a meta-analysis

Directory of Open Access Journals (Sweden)

Ai-Gui Jiang

2016-06-01

Full Text Available Aim of the study : Recent studies have suggested that k-RAS mutations are related to the response to epidermal growth factor receptor (EGFR tyrosine-kinase inhibitions (TKIs in advanced non-small cell lung cancer (NSCLC treatment. The aim of this meta-analysis was to assess the relationship between smoking history and k-RAS mutations in NSCLC treated with TKIs. Material and methods : We searched MEDLINE and Web of Science up to 15 March 2014. The pooled relative risk (RR was estimated by using fixed effect model or random effect model, according to heterogeneity between studies. We also carried out power analyses. Results : We identified 12 studies with 1193 patients, including 196 patients (16.4% with k-RAS mutations. The pooled k-RAS mutations incidence was 22.8% (174/764 in patients with smoke expose vs. 5.4% (23/429 in those with no smoke exposure. The pooled RR was 2.991 (95% CI: 1.884–4.746; Z = 4.65, p = 0.000. No publication bias was found (Begg’s test: z = 1.09, p = 0.274 and Egger’s test: t = 1.38, p = 0.201. In subgroup analyses, the pooled RR was 3.336 (95% CI: 1.925–5.779; Z = 4.30, p = 0.000 in the Caucasian subgroup, while in the Asian subgroup the pooled RR was 2.093 (95% CI: 0.909–4.822; Z = 1.73, p = 0.083, but the sample size was underpowered (0.465. Conclusions : The current meta-analysis found that smoking was related to increased incidence of k-RAS mutations in non-small cell lung cancer treated with TKIs. This may be further evidence that smoking will lead to a worse prognosis in NSCLC patients treated with TKIs.

Comparative Survival in Patients With Postresection Recurrent Versus Newly Diagnosed Non-Small-Cell Lung Cancer Treated With Radiotherapy

International Nuclear Information System (INIS)

Cai Xuwei; Xu Luying; Wang Li; Hayman, James A.; Chang, Andrew C.; Pickens, Allan; Cease, Kemp B.; Orringer, Mark B.; Kong, F.-M.

2010-01-01

Purpose: To compare the survival of postresection recurrent vs. newly diagnosed non-small-cell lung cancer (NSCLC) patients treated with radiotherapy or chemoradiotherapy. Methods and Materials: The study population consisted of 661 consecutive patients with NSCLC registered in the radiation oncology databases at two medical centers in the United States between 1992 and 2004. Of the 661 patients, 54 had postresection recurrent NSCLC and 607 had newly diagnosed NSCLC. Kaplan-Meier and Cox regression models were used for the survival analyses. Results: The distribution of relevant clinical factors between these two groups was similar. The median survival time and 5-year overall survival rates were 19.8 months (95% confidence interval [CI], 13.9-25.7) and 14.8% (95% confidence interval, 5.4-24.2%) vs. 12.2 months (95% CI, 10.8-13.6) and 11.0% (95% CI, 8.5-13.5%) for recurrent vs. newly diagnosed patients, respectively (p = .037). For Stage I-III patients, no significant difference was observed in the 5-year overall survival (p = .297) or progression-free survival (p = .935) between recurrent and newly diagnosed patients. For the 46 patients with Stage I-III recurrent disease, multivariate analysis showed that chemotherapy was a significant prognostic factor for 5-year progression-free survival (hazard ratio, 0.45; 95% CI, 0.224-0.914; p = .027). Conclusion: Our institutional data have shown that patients with postresection recurrent NSCLC achieved survival comparable to that of newly diagnosed NSCLC patients when they were both treated with radiotherapy or chemoradiotherapy. These findings suggest that patients with postresection recurrent NSCLC should be treated as aggressively as those with newly diagnosed disease.

Non-protected operators in N=4 SYM and multiparticle states of AdS5 SUGRA