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Sample records for munich tandem accelerator

  1. High-sensitivity AMS for heavy nuclides at the Munich Tandem accelerator

    CERN Document Server

    Knie, K; Korschinek, G; Rugel, G; Rühm, W; Wallner, C

    2000-01-01

    During the last years we have aimed at utilizing the high energy achievable at the Munich MP Tandem (TV=14 MV) for maximum sensitivity. One of our interests is the measurements of radionuclides around A=60 ( sup 5 sup 3 Mn, sup 6 sup 0 Fe, sup 6 sup 3 Ni) because of their high scientific potentials. However, in this mass region there are usually strong limitations in sensitivity due to a large isobaric background. Its suppression is performed by means of a gas-filled magnet and a multi DELTA E ionization chamber. A Wien filter and a time-of-flight path allow a further suppression of (non-isobaric) background. The optimization of the setup as a whole yielded detection limits of sup 5 sup 3 Mn/Mn approx 2x10 sup - sup 1 sup 4 sup 6 sup 3 Ni/Ni approx 2x10 sup - sup 1 sup 4 and sup 6 sup 0 Fe/Fe approx 2x10 sup - sup 1 sup 6 , which presently cannot be achieved by any other detection method. The overall efficiency (including ion source) is typically 10 sup - sup 5 -10 sup - sup 4. The gas-filled magnet allows an...

  2. MAFF – The Munich accelerator for fission fragments

    Indian Academy of Sciences (India)

    L Beck; D Habs; P Reiter; P Thirolf; T Seiber; H Bongers; S Emhofer; H Maier

    2002-12-01

    At the new high flux reactor FRM-II in Munich the accelerator MAFF (Munich accelerator for fission fragments) is under design. In the high neutron flux of 1014 n/cm2 s up to 1014 neutron-rich fission fragments per second are produced in the 1 g U-235 target. Ions with an energy of 30 keV are extracted from the ion source. In the mass seperator two isotopes can be selected. One of the beams is used for low energy experiments, the other one is injected into an ECRIS (or EBIS) for charge breeding to a / ≥ 0.16. A gas filled RFQ cooler is used for emittance improvement. The subsequent LINAC delivers beams with an energy ranging from 3.7 MeV/u to 5.9 MeV/u. New IH structures are being developed at the Munich tandem laboratory. A small storage ring is planned in a further stage to recycle the fission fragments. A thin target foil can be placed into this ring, e.g., for synthesis of super-heavy elements. The through-going beam tube has been installed in the heavy water tank of the reactor. Tests of the target ion source in a special oven to test long term stability and safety tests were in progress.

  3. Target development for the Munich fission fragment accelerator

    CERN Document Server

    Maier, H J; Gross, M L; Grossmann, R; Kester, O; Thirolf, P

    2002-01-01

    The target for the Munich Fission Fragment Accelerator (MAFF) consists of typically 1 g of the fission material sup 2 sup 3 sup 5 U in the form of UC sub 2 , dispersed homogeneously in a cylindrical graphite matrix, which is encapsulated in a protective Re container. This special type of target is currently under development. The problems related to its manufacture are discussed. To enable diffusion and extraction of the fission products, the target has to be maintained at a temperature of up to 2700 K during operation. Extensive tests are required to study the long-term behaviour of the involved materials at these conditions. For this purpose a resistively heated high vacuum furnace has been set up, which allows high-temperature heat treatment of target samples for a period of up to 1000 h.

  4. A distributed control system status report of the munich accelerator control

    Science.gov (United States)

    Rohrer, L.; Schnitter, H.

    1999-04-01

    A system of computers connected by a local area network (ARCNET®) controls the Munich accelerator facility. This includes ion sources, the tandem accelerator, the beam transport system, the gas handling plant, parts of experimental setup and also an ion source test bench. ARCNET is a deterministic multi-master network with arbitrary topology, using coax cables and optical fibers. Crates with single board computers and I/O-boards (analog, parallel or serial digital), dependent on the devices being controlled, are distributed all over the building. Personal computers serve as user interfaces. The LAN communication protocol is a client/server protocol. Communication language and programming language for the single board computers is Forth. The user mode drivers in the personal computers are also written in Forth. The tools for the operators are MS-Windows applications, programmed in Forth, C++ or Visual Basic. Links to MS-Office applications are available, too.

  5. Target conception for the Munich fission fragment accelerator

    CERN Document Server

    Maier, H J; Gross, M L; Grossmann, R; Kester, O; Thirolf, P

    1999-01-01

    For the new high-flux reactor FRM II, the fission fragment accelerator MAFF is under design. MAFF will supply intense mass-separated radioactive ion beams of very neutron-rich nuclei with energies around the Coulomb barrier. A central part of this accelerator is the ion source with the fission target, which is operated at a neutron flux of 1.5x10 sup 1 sup 4 cm sup - sup 2 s sup - sup 1. The target consists of typically 1 g of sup 2 sup 3 sup 5 U dispersed in a cylindrical graphite matrix, which is encapsulated in a Re container. To enable diffusion and extraction of the fission products, the target has to be maintained at a temperature of up to 2400 deg. C during operation. It has to stand this temperature for at least one reactor cycle of 1250 h. Comprehensive tests are required to study the long-term behaviour of the involved materials at these conditions prior to operation in the reactor. The present paper gives details of the target conception and the projected tests.

  6. A study of reflex tandem accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Nakajima, Takao; Morinobu, Shunpei; Gono, Yasuyuki; Sagara, Kenji; Sugimitsu, Tsuyoshi; Mitarai, Shiro; Nakamura, Hiroyuki; Ikeda, Nobuo; Morikawa, Tsuneyasu [Kyushu Univ., Fukuoka (Japan). Faculty of Science

    1996-12-01

    An investigation on `developing research theme and its realizing experimental apparatus` based on the tandem accelerator facility is executed. At a standpoint of recognition on essentiality of preparation, improvement or novel technical development capable of extreme increase in capacity of the tandem accelerator facility to form COE with high uniqueness, proposal of numerous ideas and their investigations and searches were conducted. In this paper, consideration results of `beam reacceleration using tandem accelerator` were shown as follows: (1) Short life unstable nuclei formed by nuclear reaction using tandem acceleration primary beam is ionized to negative and to reaccelerate by using the same tandem accelerator. And (2) by combination of plural electrons with the tandem primary accelerated beam, numbers of charge is reduced to reaccelerate by the tandem. (G.K.)

  7. JAERI tandem-accelerator and tandem-booster

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, Tadashi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-03-01

    In 1982, aiming at the new development of atomic energy research, the tandem accelerator of Japan Atomic Energy Research Institute (JAERI) was installed. In fiscal year 1993, the superconducting boosters which can increase the ion energy by up to 4 times were added, and the research in the region below 1000 MeV became possible. Those are electrostatic type accelerators which are easy to be used especially in basic research field, and are useful for future research. The tandem accelerator has been operated while maintaining the first class performance as the accelerator for various kinds of heavy ion beam. It has the special shape among electrostatic type accelerators, and is excellent in the easiness of control and stability. The main particulars of the tandem accelerator are shown. As for the ion sources of the tandem accelerator, three cesium sputter type ion sources are installed on two high voltage stands. The kinds of the ions which can be accelerated are mainly negative ions. As the improvement, electron cyclotron resonance (ECR) ion sources are expected to be adopted. As for the tandem boosters, the 1/4 wavelength type resonance hollow cylinder was adopted. The constitution of the tandem boosters is explained. The way of utilizing the tandem accelerator system and the aim for hereafter are reported. (K.I.)

  8. JAERI tandem-accelerator and tandem-booster

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, Tadashi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-03-01

    In 1982, aiming at the new development of atomic energy research, the tandem accelerator of Japan Atomic Energy Research Institute (JAERI) was installed. In fiscal year 1993, the superconducting boosters which can increase the ion energy by up to 4 times were added, and the research in the region below 1000 MeV became possible. Those are electrostatic type accelerators which are easy to be used especially in basic research field, and are useful for future research. The tandem accelerator has been operated while maintaining the first class performance as the accelerator for various kinds of heavy ion beam. It has the special shape among electrostatic type accelerators, and is excellent in the easiness of control and stability. The main particulars of the tandem accelerator are shown. As for the ion sources of the tandem accelerator, three cesium sputter type ion sources are installed on two high voltage stands. The kinds of the ions which can be accelerated are mainly negative ions. As the improvement, electron cyclotron resonance (ECR) ion sources are expected to be adopted. As for the tandem boosters, the 1/4 wavelength type resonance hollow cylinder was adopted. The constitution of the tandem boosters is explained. The way of utilizing the tandem accelerator system and the aim for hereafter are reported. (K.I.)

  9. Status of JAERI tandem accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, Tadashi; Kanda, Susumu; Takeuchi, Suehiro [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment] (and others)

    2001-02-01

    JAERI Tandem Accelerator had been operated approximately 230 days in fiscal year of 1999. Meanwhile, we had three times of maintenance period with vent. Total operation-times were 5273 hours. We could not carry out the experiment using rare gas, due to malfunction of the RF power supply for the ECR ion source. The type of the RF power supply is peculiar and it is impossible to get spare parts for repair. We are now investigating the backup RF power supply. The power supply for the magnet became unstable due to degradation of insulation in the shunt resistance, which is used for feedback stabilization. Stability was recovered after cleaning. The acrylic resin shaft was cracked. This cracks have a potential for severe accidents. So far bearing of the shaft has no problem. The reason of cracks may be self-destruction by charge accumulation in the shaft. JAERI Tandem Accelerator is approximately 20 years old. There appear requirements on the higher ion currents for additional ion species. Therefore, authors are investigating cost effective improvement plans of RFQ (Radio Frequency Quadra-pole) and IH type accelerator based on KEK (High Energy Accelerator Research Organization) R and D. As a whole, maintenance services for the control system are increasing due to some changes of computer programs. There are some difficulties to keep skilled personnel for facilities operation. Authors are gradually increasing hired personnel with contract from 1993. However, loads for JAERI permanent staffs are still heavy. It takes much longer time to educate skilled persons especially for safety. (Y. Tanaka)

  10. The PSI/ETH tandem accelerator facility

    Energy Technology Data Exchange (ETDEWEB)

    Synal, H.A.; Doebeli, M.; Fuhrmann, H.; Kubik, P.W.; Nebiker, P.W. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)] [and others

    1997-09-01

    The 1996 operation of the PSI/ETH tandem accelerator at ETH Hoenggerberg is summarised with a detailed compilation of the beam time statistics and the statistics of AMS samples for the different radioisotopes and for the major fields of research. (author) 2 tab.

  11. HRIBF Tandem Accelerator Radiation Safety System Upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Blankenship, J.L.; Juras, R.C.

    1998-11-04

    The HRIBF Tandem Accelerator Radiation Safety System was designed to permit experimenters and operations staff controlled access to beam transport and experiment areas with accelerated beam present. Neutron-Gamma detectors are mounted in eaeh area at points of maximum dose rate and the resulting signals are integrated by redundan~ circuitry; beam is stopped if dose rate or integrated dose exceeds established limits. This paper will describe the system, in use for several vears at the HRIBF, and discuss changes recently made to modernize the system and to make the system compliant with DOE Order 5480.25 and related ORNL updated safety rules.

  12. Folded tandem ion accelerator facility at Trombay

    Indian Academy of Sciences (India)

    P Singh

    2001-08-01

    The folded tandem ion accelerator (FOTIA) project at BARC has been commissioned. The analysed carbon beams of 40 nA(3+) and 25 nA(4+), at terminal voltage of 2.5 MV with N2 + CO2 as insulating gas, were obtained. The beams were characterized by performing the Rutherford back scattering (RBS) on gold, tin and iron targets. The beam energy of 12.5 MeV for 12C4+ was consistent with the terminal voltage of 2.5 MV. The N2 + CO2 mixture is being replaced by SF6 gas in order to achieve 6 MV on the terminal. In this paper, some of the salient features of the FOTIA and its present status are discussed.

  13. Beam optics of the folded tandem ion accelerator at BARC

    Indian Academy of Sciences (India)

    S Santra; P Singh

    2002-07-01

    The beam optics of the 6 MV folded tandem ion accelerator, that has recently been commissioned at Bhabha Atomic Research Centre, Mumbai, is presented. Typical beam trajectories for proton and 12C beams under different conditions, are shown. The constraints on the design due to the use of the infrastructure of the Van de Graaff accelerator, which existed earlier, are discussed.

  14. Annual Report of HI-13 Tandem Accelerator in 2013

    Institute of Scientific and Technical Information of China (English)

    KAN; Chao-xin; HU; Yue-ming; BAO; Yi-wen; FAN; Hong-sheng

    2013-01-01

    HI-13 tandem accelerator was running well in 2013,some good works were doing well in maintenance and development.This year the machine has been operated 4 000 hours,and provided beam time 3 100 hours for more than 50 experiment users,the terminal voltage range is from 3 MV to 12.3 MV.1 Operation In 2013,HI-13 tandem accelerator provided 16 kinds of ions.The distribution of beam time versus ion is shown in Fig.1.

  15. Status report on the folded tandem ion accelerator at BARC

    Indian Academy of Sciences (India)

    P Singh; S K Gupta; M J Kansara; A Agarwal; S Santra; Rajesh Kumar; A Basu; P Sapna; S P Sarode; N B V Subrahmanyam; J P Bhatt; P J Raut; S S Pol; P V Bhagwat; S Kailas; B K Jain

    2002-11-01

    The folded tandem ion accelerator (FOTIA) facility set up at BARC has become operational. At present, it is used for elemental analysis studies using the Rutherford backscattering technique. The beams of 1H, 7Li, 12C, 16O and 19F have been accelerated up to terminal voltages of about 3 MV and are available for experiments. The terminal voltage is stable within ± 2 kV. In this paper, present status of the FOTIA and future plans are discussed.

  16. The status of the tandem accelerator ANTARES

    Energy Technology Data Exchange (ETDEWEB)

    Fallon, J.; Boldeman, J.; Cohen, D.; Tuniz, C.; Ellis, P. [Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW (Australia)

    1996-12-31

    The ANTARES facility at the Lucas Heights Research Laboratories has now operated for 4 years. A research program in Accelerator Mass Spectrometry, lon Beam Analysis and small scale radioisotope production has been pursued. During the same period, the accelerator has been significantly upgraded from the configuration which existed at Rutgers University, NJ, USA, before shipment to Australia in 1989. AMS measurement techniques of several long lived isotopes have been developed for environmental, industry and biomedical applications. Both the experimental program and the engineering developments are discussed further.

  17. Polarized ionic source of the tandem accelerator in Kyoto University

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, Masanobu; Kuwamoto, Shuichi; Takahashi, Seiji [Kyoto Univ. (Japan). Dept. of Physics] [and others

    1997-02-01

    A polarized ion source developed under the National Laboratory of High Energy Physics was transferred to the tandem accelerator in Kyoto University at beginning of 1993 to constitute a displacement of incidence into the accelerator. This was an atomic beam type polarized ion source, which is designed to adopt permanent magnets for 6 poles magnet to polarize the electron, to take out atomic nucleus on a shape of positive ion by ECR ionizer after transferring its polarization through transition using radio frequency (RFT), to make it negative ion by charge conversion using alkaline metal vapor, and to put it into the tandem accelerator. Test of the positive ion was finished at the National Laboratory of High Energy Physics, and test in Kyoto University was required after its negative ionization. As the estimated cost was unsufficient and entrance into the ion source facility in the tandem accelerator building was limited in Kyoto University, step of development was slow. Here is reported on present state of the ion source which is now operating stably. (G.K.)

  18. Annual Report of HI-13 Tandem Accelerator in 2012

    Institute of Scientific and Technical Information of China (English)

    KAN; Chao-xin; HU; Yue-ming; BAO; Yi-wen; FAN; Hong-sheng

    2012-01-01

    <正>HI-13 tandem accelerator was running well in 2012, some good works were doing well in maintenance and development. This year the machine has been operated 3 600 h, and provided beam time 3 200 h for more than 40 experiment users, the terminal voltage range is from 3 MV to 12 MV. From 1988 to June of 2012, the machine had been running safety for 100 000 h.

  19. Sulphur hexafluoride as a stripper gas for tandem accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Hotchkis, M.A.C., E-mail: mah@ansto.gov.au; Child, D.; Fink, D.; Garton, D.; Levchenko, V.; Wilcken, K.

    2013-05-01

    Highlights: •Sulphur hexafluoride is investigated as a stripper gas in tandem accelerators. •For heavy ions at low terminal voltage, mean charge states are found to be up to 1 charge unit higher than with argon gas. •Charge state distributions are found to be broader than with argon gas. •For charge states above the mean charge state, yields are typically doubled using SF{sub 6}. •Using SF{sub 6} stripper gas, the efficiency of actinides AMS analysis is doubled. -- Abstract: We have investigated sulphur hexafluoride as a stripper gas in tandem accelerators by using the ANTARES accelerator system at ANSTO to measure charge state distributions for this gas. Results are reported at 4 MV terminal voltage for injected negative ions ranging from carbon to uranium oxide. For iodine and thorium the distributions are extended across a range of energies of practical use for accelerator mass spectrometry, ion beam analysis and other accelerator applications. Charge state distributions using sulphur hexafluoride are found to have mean charge states up to 1 charge unit higher than, and to be broader than, corresponding distributions for argon gas, except in the case of carbon beams. As a result, SF{sub 6} is shown to provide significantly higher yields for charge states of heavy ions above the mean charge state. We now perform actinide AMS measurements with 9% yield to the 5+ charge state, compared to 4–5% achieved previously with argon gas.

  20. Sulphur hexafluoride as a stripper gas for tandem accelerators

    Science.gov (United States)

    Hotchkis, M. A. C.; Child, D.; Fink, D.; Garton, D.; Levchenko, V.; Wilcken, K.

    2013-05-01

    We have investigated sulphur hexafluoride as a stripper gas in tandem accelerators by using the ANTARES accelerator system at ANSTO to measure charge state distributions for this gas. Results are reported at 4 MV terminal voltage for injected negative ions ranging from carbon to uranium oxide. For iodine and thorium the distributions are extended across a range of energies of practical use for accelerator mass spectrometry, ion beam analysis and other accelerator applications. Charge state distributions using sulphur hexafluoride are found to have mean charge states up to 1 charge unit higher than, and to be broader than, corresponding distributions for argon gas, except in the case of carbon beams. As a result, SF6 is shown to provide significantly higher yields for charge states of heavy ions above the mean charge state. We now perform actinide AMS measurements with 9% yield to the 5+ charge state, compared to 4-5% achieved previously with argon gas.

  1. Development of high current injector for tandem accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Baba, Takashi; Iwamoto, Eiji [Nissin - High Voltage Co. Ltd., Kyoto (Japan); Kishimoto, Naoki; Saito, Tetsuya; Mori, Yoshiharu

    1997-02-01

    The development of the electrostatic type tandem accelerators has been carried out so far, but by the recent remarkable progress of negative ion sources, the beam current which was inconceivable so far has become obtainable, and the use as the electrostatic type tandem accelerators is expanding rapidly. The problem which must be solved in the development of a high energy, large current heavy ion injection device is the development of an injector. As to the generation of negative ions, by the development of plasma sputter negative ion sources, the almost satisfactory performance has been obtained in beam current, emittance, life and so on, but as for the transport and control of generated negative ion beam, there is the large problem of spatial charge effect. This time, the verifying test on this problem was carried out, therefore, its contents and results are reported. The equipment which was developed this time was delivered to the Institute for Materials Research. Its specifications are shown. The whole constitution, negative ion source, and beam transport system are described. Beam generation test and spatial charge effect test are reported. The test stand was made, and in the verifying test, the maximum beams of 4 mA in Cu and 3 mA in Ni were able to be generated and transported. The effect of the countermeasures to spatial charge effect was confirmed. (K.I.)

  2. Actualization of the Tandem-E N Accelerator of the Nuclear Centre of Mexico; Actualizacion del Acelerador Tandem-EN del Centro Nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Villasenor S, P.; Aguilera R, E.; Aspiazu F, J.; Fernandez A, J.; Fernandez B, M.; Garcia R, B.; Lopez M, J.; Martinez Q, E.; Mendez G, B.; Moreno B, E.; Murillo O, G.; Policroniades R, R.; Ramirez T, J.; Reynoso V, R.; Varela G, A.; Vega C, J. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)

    2004-07-01

    In this work, the activities are described carried out to change the tubes accelerators and original resistances of the accelerator Tandem-E N of the Nuclear Center, for tubes DOWLISH and resistances again design, both donated ones for ORNL. This way same, the problem is described that imply this changes, and like it was solved by the personnel of the laboratory, without having to appeal to external services, what there is redounded in a considerable increment in the costs. In form preliminary the improvements are described observed after the rehabilitation of the Accelerator. (Author)

  3. Acceleration of cluster and molecular ions by TIARA 3 MV tandem accelerator

    CERN Document Server

    Saitoh, Y; Tajima, S

    2000-01-01

    We succeeded in accelerating molecular and cluster ions (B sub 2 sub - sub 4 , C sub 2 sub - sub 1 sub 0 , O sub 2 , Al sub 2 sub - sub 4 , Si sub 2 sub - sub 4 , Cu sub 2 sub - sub 3 , Au sub 2 sub - sub 3 , LiF, and AlO) to MeV energies with high-intensity beam currents by means of a 3 MV tandem accelerator in the TIARA facility. These cluster ions were generated by a cesium sputter-type negative ion source. We tested three types of carbon sputter cathodes in which graphite powder was compressed with different pressures. The pressure difference affected the generating ratio of clusters generated to single atom ions extracted from the source and it appeared that the high-density cathode was suitable. We also investigated the optimum gas pressure for charge exchange in the tandem high-voltage terminal. Clusters of larger size tend to require lower pressure than do smaller ones. In addition, we were able to obtain doubly charged AlO molecular ions. (authors)

  4. Proceedings of the 13th meeting for tandem accelerators and related techniques

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-02-01

    The 13th Meeting for Tandem Accelerators and Related Techniques was held on June 8-9, 2000 at Mutsu, Aomori Prefecture, under the auspices of Marine Research Laboratory, Mutsu Establishment, the Japan Atomic Energy Research Institute. About 60 people participated in the meeting from 27 universities and organizations, many of which have a tandem accelerator or an electrostatic accelerator. The objectives of the meeting are to exchange information on tandem accelerates or electrostatic accelerators by making a presentation on related research and topics, and also to enhance mutual friendship of participants, resulting in the contribution to associated R and D. The meeting mainly consisted of presentations by participants and corresponding Q and A; the present situation on facilities of accelerator mass spectrometers (AMS), operations of and research on tandem accelerators or electrostatic accelerators, applications of AMS, related techniques and applications using accelerators, and so on. This report summarizes the contents of presentations made in the meeting. The 30 of the presented papers are indexed individually. (J.P.N.)

  5. Paediatrics: messages from Munich

    Directory of Open Access Journals (Sweden)

    Fabio Midulla

    2015-05-01

    Full Text Available The aim of this article is to describe paediatric highlights from the 2014 European Respiratory Society (ERS International Congress in Munich, Germany. Abstracts from the seven groups of the ERS Paediatric Assembly (Respiratory Physiology and Sleep, Asthma and Allergy, Cystic Fibrosis, Respiratory Infection and Immunology, Neonatology and Paediatric Intensive Care, Respiratory Epidemiology, and Bronchology are presented in the context of the current literature.

  6. Accelerated radiation damage test facility using a 5 MV tandem ion accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Wady, P.T., E-mail: paul.wady@manchester.ac.uk [Dalton Cumbrian Facility, University of Manchester, Westlakes Science & Technology Park, Moor Row, Cumbria CA24 3HA (United Kingdom); Draude, A.; Shubeita, S.M.; Smith, A.D.; Mason, N. [Dalton Cumbrian Facility, University of Manchester, Westlakes Science & Technology Park, Moor Row, Cumbria CA24 3HA (United Kingdom); Pimblott, S.M. [Dalton Cumbrian Facility, University of Manchester, Westlakes Science & Technology Park, Moor Row, Cumbria CA24 3HA (United Kingdom); School of Chemistry, University of Manchester, Oxford Road, Manchester M13 9PL (United Kingdom); Jimenez-Melero, E. [Dalton Cumbrian Facility, University of Manchester, Westlakes Science & Technology Park, Moor Row, Cumbria CA24 3HA (United Kingdom); School of Materials, University of Manchester, Oxford Road, Manchester M13 9PL (United Kingdom)

    2016-01-11

    We have developed a new irradiation facility that allows to perform accelerated damage tests of nuclear reactor materials at temperatures up to 400 °C using the intense proton (<100 μA) and heavy ion (≈10 μA) beams produced by a 5 MV tandem ion accelerator. The dedicated beam line for radiation damage studies comprises: (1) beam diagnosis and focusing optical components, (2) a scanning and slit system that allows uniform irradiation of a sample area of 0.5–6 cm{sup 2}, and (3) a sample stage designed to be able to monitor in-situ the sample temperature, current deposited on the sample, and the gamma spectrum of potential radio-active nuclides produced during the sample irradiation. The beam line capabilities have been tested by irradiating a 20Cr–25Ni–Nb stabilised stainless steel with a 3 MeV proton beam to a dose level of 3 dpa. The irradiation temperature was 356 °C, with a maximum range in temperature values of ±6 °C within the first 24 h of continuous irradiation. The sample stage is connected to ground through an electrometer to measure accurately the charge deposited on the sample. The charge can be integrated in hardware during irradiation, and this methodology removes uncertainties due to fluctuations in beam current. The measured gamma spectrum allowed the identification of the main radioactive nuclides produced during the proton bombardment from the lifetimes and gamma emissions. This dedicated radiation damage beam line is hosted by the Dalton Cumbrian Facility of the University of Manchester.

  7. Accelerator mass spectrometry of the heaviest long-lived radionuclides with a 3-MV tandem accelerator

    Indian Academy of Sciences (India)

    Christof Vockenhuber; Robin Golser; Walter Kutschera; Alfred Priller; Peter Steier; Stephan Winkler; Vitaly Liechtenstein

    2002-12-01

    A 3-MV pelletron tandem accelerator is the heart of the Vienna environmental research accelerator (VERA). The original design of the beam transport components allows the transport of ions of all elements, from the lightest to the heaviest. For light ions the suppression of neighboring masses was sufficient to measure isotopic ratios of 14C/12C and 26Al/27Al as low as 10-15 and 10Be/9Be down to 10-13. To suppress neighboring masses for the heaviest radionuclides in the energy range of 10–20 MeV, the resolution of VERA was increased both by improving the ion optics of existing elements at the injection side and by installing a new high-resolution electrostatic separator at the high-energy side. Interfering ions which pass all beam filters are identified with a Bragg-type ionization detector and a high-resolution time-of-flight system. Two ultra-thin diamond-like carbon (DLC) foils are used in the start and stop detector, which substantially reduces losses due to beam straggling. This improved set up enables us to measure even the heaviest long-lived radionuclides, where stable isobaric interferences are absent (e.g. 236U and 244Pu), down to environmental levels. Moreover, the advantage of a ‘small’ and well manageable machine like VERA lies in its higher stability and reliability which allows to measure these heavy radionuclides more accurately, and also a large number of samples.

  8. Development of Tandem Accelerator Mixed Target Cone and Its Application for Single Event Effects Experiments

    Institute of Scientific and Technical Information of China (English)

    CAI; Li; SHEN; Dong-jun; YOU; Qu-bo; WANG; Hui

    2012-01-01

    <正>For carrying out heavy ion single event effects (SEE) test, the tandem accelerator has the advantage of rapid replacement of ion species, making it possible to replace 5 or 6 kinds of ion in one experiment (about 20 h) and get complete cross-section curve for devices under test (DUTs). In order to achieve the purpose of rapid replacement of ion species, multi-element mixed target cone using in tandem accelerator has been developed. In this way variety of ions can be extracted in one target cone, the time of replacing target cone can be saved, thereby further raise efficiency of experiment.

  9. Annual report of the Tandem Accelerator Center, University of Tsukuba. April 1, 1996 - March 31, 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    The 12 UD Pelletron tandem accelerator has been operated successfully from April, 1996 to January, 1997. Although the operation of the accelerator became unstable in the middle of January, it was a short period. The research in the Tandem Accelerator Center covers wide fields, that is, polarization phenomena in nuclear reactions, the nonresonant breakup of Li-7, the further refinement of the CDCC theory, fusion and fission in heavy ion reactions, nuclear structure physics by means of in-beam {gamma} ray spectroscopy, solid state physics using fast ion bemas, Moessbauer effect, NMR, the application of accelerated ion beams to PIXE, and accelerator mass spectrometry. In addition, two major installations were carried out in this academic year. One is a small tandem accelerator which was moved from Electrotechnical Laboratory in Tsukuba, and the other is a system for the production and analysis of atomic clusters. The research activities at the accelerator and experimental facilities and on experimental nuclear physics, theoretical nuclear physics, atomic and solid state physics, cluster science, and ion beam application are reported in this book. Also the list of the publications by these groups is given. Ph. D. and M. Sc. theses are listed, and the speakers and the titles of seminars are reported. (K.I.)

  10. Electrostatic design and beam transport for a folded tandem electrostatic quadrupole accelerator facility for accelerator-based boron neutron capture therapy

    Energy Technology Data Exchange (ETDEWEB)

    Thatar Vento, V., E-mail: Vladimir.ThatarVento@gmail.com [Gerencia de Investigacion y Aplicaciones, CNEA, Av. Gral. Paz 1499 (1650), San Martin, Buenos Aires (Argentina)] [CONICET, Av. Rivadavia 1917 (1033), Ciudad Autonoma de Buenos Aires (Argentina); Bergueiro, J.; Cartelli, D. [Gerencia de Investigacion y Aplicaciones, CNEA, Av. Gral. Paz 1499 (1650), San Martin, Buenos Aires (Argentina)] [CONICET, Av. Rivadavia 1917 (1033), Ciudad Autonoma de Buenos Aires (Argentina); Valda, A.A. [Gerencia de Investigacion y Aplicaciones, CNEA, Av. Gral. Paz 1499 (1650), San Martin, Buenos Aires (Argentina)] [Escuela de Ciencia y Tecnologia, UNSAM, M. Irigoyen 3100 (1650), San Martin, Buenos Aires (Argentina); Kreiner, A.J. [Gerencia de Investigacion y Aplicaciones, CNEA, Av. Gral. Paz 1499 (1650), San Martin, Buenos Aires (Argentina)] [CONICET, Av. Rivadavia 1917 (1033), Ciudad Autonoma de Buenos Aires (Argentina)] [Escuela de Ciencia y Tecnologia, UNSAM, M. Irigoyen 3100 (1650), San Martin, Buenos Aires (Argentina)

    2011-12-15

    Within the frame of an ongoing project to develop a folded Tandem-Electrostatic-Quadrupole (TESQ) accelerator facility for Accelerator-Based Boron Neutron Capture Therapy (AB-BNCT), we discuss here the electrostatic design of the machine, including the accelerator tubes with electrostatic quadrupoles and the simulations for the transport and acceleration of a high intensity beam.

  11. Automated accelerator controls for a 3 MV tandem Pelletron

    Science.gov (United States)

    Rathmell, R. D.; Kitchen, R. L.; Luck, T. R.; Sundquist, M. L.

    1991-05-01

    A new accelerator control system has been developed which uses a real-time, multitasking operating system running on a Motorola 68030 based microcomputer. The system includes multiple graphic and text displays and allows the operator to communicate via these displays to the accelerator, which is interfaced to CAMAC. Most accelerator parameters can be controlled using a mouse in conjunction with a single graphic display, eliminating the need to change CRT pages in order to control parameters from the source to the target. A touch screen is also available to permit a number of parameters to be at the operator's finger tips at all times. Operating parameters for a new beam and energy can be automatically set by scaling from a previously stored run. The program and database are structured to facilitate interlocking and closed loop control of parameters. The hardware configuration, structure and features of the software will be reviewed.

  12. Half-life of Si-32 from tandem-accelerator mass spectrometry

    Science.gov (United States)

    Elmore, D.; Anantaraman, N.; Fulbright, H. W.; Gove, H. E.; Nishiizumi, K.; Murrell, M. T.; Honda, M.; Hans, H. S.

    1980-01-01

    A newly developed mass-spectrometry technique employing a tandem Van de Graaff accelerator together with a special beam-transport system and heavy-ion detector has been used to determine the half-life of Si-32. The result obtained, 108 plus or minus 18 yr, disagrees with the accepted value of 330 plus or minus 40 yr. The implications of the new half-life of Si-32, which is used for dating studies, are discussed.

  13. In-terminal ECR Ion Source of the Tandem Accelerator at JAERI

    CERN Document Server

    Matsuda, M; Takeuchi, S

    1999-01-01

    Electron Cyclotron Resonance Ion Source(ECRIS)s are able to produce intense beams of highly charged positive ions and used injection system for cyclotron, linac as well as experiments of atomic physics. The tandem accelerator system has been benefiting from use of an electron stripper at the high voltage terminal. The most probable charged state after a foil stripper is, however, much lower than the highest charge state of ions with an intensity of more than several emA from a high performance ECRIS. With respect to beam current, the life time of stripper foils decrease with increasing beam current. Especially for very heavy ions, it is difficult to obtain a stable and intense beam for a long time without foil exchange. Use of an ECRIS in a tandem accelerator is expected to increase beam intensity, beam energy and beam species. A small permanent magnet ECRIS has been installed in the high voltage terminal of the vertical and folded type 20UR Pelletron tandem accelerator at Japan Atomic Energy Research Institu...

  14. Development of a Tandem-Electrostatic-Quadrupole facility for Accelerator-Based Boron Neutron Capture Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Kreiner, A.J., E-mail: kreiner@tandar.cnea.gov.ar [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica, Av. Gral Paz 1499, 1650 San Martin, Buenos Aires (Argentina)] [Escuela de Ciencia y Tecnologia, Universidad Nacional de San Martin (Argentina)] [CONICET, Buenos Aires (Argentina); Castell, W. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica, Av. Gral Paz 1499, 1650 San Martin, Buenos Aires (Argentina); Di Paolo, H. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica, Av. Gral Paz 1499, 1650 San Martin, Buenos Aires (Argentina)] [Escuela de Ciencia y Tecnologia, Universidad Nacional de San Martin (Argentina); Baldo, M. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica, Av. Gral Paz 1499, 1650 San Martin, Buenos Aires (Argentina); Bergueiro, J. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica, Av. Gral Paz 1499, 1650 San Martin, Buenos Aires (Argentina)] [CONICET, Buenos Aires (Argentina)

    2011-12-15

    We describe the present status of an ongoing project to develop a Tandem-ElectroStatic-Quadrupole (TESQ) accelerator facility for Accelerator-Based (AB)-BNCT. The project final goal is a machine capable of delivering 30 mA of 2.4 MeV protons to be used in conjunction with a neutron production target based on the {sup 7}Li(p,n){sup 7}Be reaction. The machine currently being constructed is a folded TESQ with a high-voltage terminal at 0.6 MV. We report here on the progress achieved in a number of different areas.

  15. TANDEM

    Data.gov (United States)

    Federal Laboratory Consortium — The Tandem Van de Graaff facility provides researchers with beams of more than 40 different types of ions - atoms that have been stripped of their electrons. One of...

  16. Physicists and Physics in Munich

    Science.gov (United States)

    Teichmann, Jürgen; Eckert, Michael; Wolff, Stefan

    We give a tour of Munich and some outlying sites that focuses on the lives and work of the most prominent physicists who lived in the city, Count Rumford, Joseph Fraunhofer, Georg Simon Ohm, Max Planck, Ludwig Boltzmann, Albert Einstein, Wilhelm Conrad Röntgen, Wilhelm Wien, Arnold Sommerfeld, Max von Laue, and Werner Heisenberg. We close with a self-guided tour that describes how to reach these sites in Munich.

  17. Novel tandem quadrupole-acceleration-deceleration mass spectrometer for neutralization-reionization studies.

    Science.gov (United States)

    Turecek, F; Gu, M; Shaffer, S A

    1992-07-01

    A new tandem mass spectrometer of the quadrupole-acceleration lens-deceleration. lens-quadrupole (QADQ) configuration is described. The instrument is designed for neutralization-reionization studies and consists of a 2000-u quadrupole mass analyzer as MS-I, an acceleration electrostatic lens, a series of three differentially pumped collision cells, and an electrostatic deceleration lens, energy filter, and another 2000-u quadrupole mass analyzer as MS-II. The ion optical system achieves high total ion transmission for 5-9-keV ions. Unit mass resolution in neutralization-reionization mass spectra of aromatic compounds is demonstrated. Mass, kinetic energy, and linked scans at various levels of mass resolution and sensitivity are described.

  18. Tandem accelerators in Romania: Multi-tools for science, education and technology

    Science.gov (United States)

    Burducea, I.; GhiÅ£ǎ, D. G.; Sava, T. B.; Straticiuc, M.

    2017-06-01

    An educated selection of the main beam parameters - particle type, velocity and intensity, can result in a cutting-edge scalpel to remove tumors, sanitize sewage, act as a nuclear forensics detective, date an artefact, clean up air, improve a microprocessor, transmute nuclear waste, detect a counterfeit or even look into the stars. Nowadays more than particle accelerators operate worldwide in medicine, industry and basic research. For example the proton therapy market is expected to attain 1 billion US per year in 2019 with almost 330 proton therapy rooms, while the annual market for the ion implantation industry already reached 1.5 G in revenue [1,2]. A brief history of the Tandem Accelerators Complex at IFIN-HH [3] emphasizing on their applications and the physics behind the scenes, is also presented [4-6].

  19. A Java-based control system for the Orsay tandem accelerator

    Indian Academy of Sciences (India)

    Dominique Delbourg; Gérard Penillault; Tran Khan Tuong; Martial Decourt; Nicole Borome; Henri Harroch; Bertrand Lessellier; Bernard Waast; Jean Pierre Mouffron

    2002-12-01

    A new control system was designed for the tandem MP-9 at Orsay. Because of the existing devices located on high voltage platforms and the lack of space inside the accelerator, in-house electronic cards based on micro-controllers and an optical fieldbus were developed to collect data. VME processors under VxWorks, a real time operating system, manage the fieldbus, concentrate the accelerator information and transmit it to the supervisory software through the ethernet network. This software consists of a collection of Java virtual machines (JVM) running on several Unix work-stations and PCs under Windows. Some of the Java virtual machines manage apparatus, instruments, local display and connections to an object database and VME concentrators. Others manage general synoptics. JVMs communicate between themselves with RMI protocol and JRPC with VME concentrators. So the supervisory software can be spread over several control stations throughout the network.

  20. Application of tandem accelerator mass spectrometor to the chronological study of archaeological samples on Ryukyu Islands

    Energy Technology Data Exchange (ETDEWEB)

    Taira, Hatsuo; Higa, Kenichi; Nakai, Nobuyuki; Nakamura, Toshio.

    1987-10-01

    Along with the urbanization of rural areas on Ryukyu Islands, many shell mounds and pre-historic sites have been found in resent years. Chrological studies of shell samples from these mounds will lead to the better understanding of cultural background for the pre-historic human activities on the Ryukyu Islands. C-14 dating by beta counting is the common method to obtain the ages of the archaeological samples. It is, however, very limited in obtaining the absolute ages by the above mehtod due to the large sample sizes required and time consuming. There are many newly obtained archaeological samples left unstudied in detail. The alternate is a method called Tandem Accelerator Mass Spectrometer (AMS) installed at Nagoya University, which is composed of the tandem type accelerator to measure very low concentration of C-14 in archaeological samples. The system has been designed particularly to measure the radio-carbon and has advantages of being small sample size and very little time consuming for C-14 measurement as compared with the beta counting. It is the aim of this work to apply the above AMS for obtaining the absolute ages of the archaeological samples. The results agreed well with those estimated by the Erthenware method (relative method of dating), which ranged from 500 to 6000 y.b.p. The results may be helpful for the chronological arrangement of the samples and for the understanding of pre-historical human activities on the Ryukyu Islands.

  1. Annual report of the Tandem Accelerator Center, University of Tsukuba. April 1, 1997 - March 31, 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-06-01

    This report briefly described the investigations performed during the period from April 1997 to March 1998 in Tandem Accelerator Center. The 12 UD Pelletron tandem accelerator was reconstructed and the first beam test was carried out in Nov. 1997. In nuclear physics, the measurement of total reaction cross sections, the non-resonant breakup of {sup 7}Li and {sup 9}Be, the investigation of hole states via (p,d) reaction, nuclear structure physics by means of in-beam {gamma} ray spectroscopy and the study of the three dimensional cranking model have been performed. In interdisciplinary fields, the development of AMS system has been continued. The trace element analysis of mineral samples has been carried out by means of PIXE with the proton beam which was focused on the sample as narrow as 50 {mu}m{sup 2}. The hydrogen analysis using H({sup 19}F,{alpha}{gamma}) reaction has been started aiming at the extension of the measurement of depth profile down to a few tens of {mu}m deep region. (M.N.)

  2. Development of a tandem-electrostatic-quadrupole accelerator facility for BNCT.

    Science.gov (United States)

    Kreiner, A J; Thatar Vento, V; Levinas, P; Bergueiro, J; Di Paolo, H; Burlon, A A; Kesque, J M; Valda, A A; Debray, M E; Somacal, H R; Minsky, D M; Estrada, L; Hazarabedian, A; Johann, F; Suarez Sandin, J C; Castell, W; Davidson, J; Davidson, M; Giboudot, Y; Repetto, M; Obligado, M; Nery, J P; Huck, H; Igarzabal, M; Fernandez Salares, A

    2009-07-01

    In this work we describe the present status of an ongoing project to develop a tandem-electrostatic-quadrupole (TESQ) accelerator facility for accelerator-based (AB) BNCT at the Atomic Energy Commission of Argentina in Buenos Aires. The project final goal is a machine capable of delivering 30 mA of 2.4 MeV protons to be used in conjunction with a neutron production target based on the (7)Li(p,n)(7)Be reaction slightly beyond its resonance at 2.25 MeV. These are the specifications needed to produce sufficiently intense and clean epithermal neutron beams, based on the (7)Li(p,n)(7)Be reaction, to perform BNCT treatment for deep-seated tumors in less than an hour. An electrostatic machine is the technologically simplest and cheapest solution for optimized AB-BNCT. The machine being designed and constructed is a folded TESQ with a high-voltage terminal at 1.2 MV intended to work in air. Such a machine is conceptually shown to be capable of transporting and accelerating a 30 mA proton beam to 2.4 MeV. The general geometric layout, its associated electrostatic fields, and the acceleration tube are simulated using a 3D finite element procedure. The design and construction of the ESQ modules is discussed and their electrostatic fields are investigated. Beam transport calculations through the accelerator are briefly mentioned. Likewise, work related to neutron production targets, strippers, beam shaping assembly and patient treatment room is briefly described.

  3. Development of a tandem-electrostatic-quadrupole accelerator facility for BNCT

    Energy Technology Data Exchange (ETDEWEB)

    Kreiner, A.J. [Dept. de Fisica, Comision Nacional de Energia Atomica, Av. Gral Paz 1499 (1650), San Martin, Buenos Aires (Argentina); Escuela de Ciencia y Tecnologia. Universidad Nacional de Gral. San Martin, M. De Irigoyen 3100 (1650), San Martin, Buenos Aires (Argentina); CONICET, Avda. Rivadavia 1917(C1033AAJ), Ciudad Autonoma de Buenos Aires (Argentina)], E-mail: kreiner@tandar.cnea.gov.ar; Thatar Vento, V. [Dept. de Fisica, Comision Nacional de Energia Atomica, Av. Gral Paz 1499 (1650), San Martin, Buenos Aires (Argentina); Levinas, P. [Dept. de Fisica, Comision Nacional de Energia Atomica, Av. Gral Paz 1499 (1650), San Martin, Buenos Aires (Argentina); CONICET, Avda. Rivadavia 1917(C1033AAJ), Ciudad Autonoma de Buenos Aires (Argentina); Bergueiro, J. [Dept. de Fisica, Comision Nacional de Energia Atomica, Av. Gral Paz 1499 (1650), San Martin, Buenos Aires (Argentina); Di Paolo, H.; Burlon, A.A. [Dept. de Fisica, Comision Nacional de Energia Atomica, Av. Gral Paz 1499 (1650), San Martin, Buenos Aires (Argentina); Escuela de Ciencia y Tecnologia. Universidad Nacional de Gral. San Martin, M. De Irigoyen 3100 (1650), San Martin, Buenos Aires (Argentina); Kesque, J.M. [Dept. de Fisica, Comision Nacional de Energia Atomica, Av. Gral Paz 1499 (1650), San Martin, Buenos Aires (Argentina); Valda, A.A.; Debray, M.E.; Somacal, H.R. [Dept. de Fisica, Comision Nacional de Energia Atomica, Av. Gral Paz 1499 (1650), San Martin, Buenos Aires (Argentina); Escuela de Ciencia y Tecnologia. Universidad Nacional de Gral. San Martin, M. De Irigoyen 3100 (1650), San Martin, Buenos Aires (Argentina); Minsky, D.M. [Dept. de Fisica, Comision Nacional de Energia Atomica, Av. Gral Paz 1499 (1650), San Martin, Buenos Aires (Argentina); Escuela de Ciencia y Tecnologia. Universidad Nacional de Gral. San Martin, M. De Irigoyen 3100 (1650), San Martin, Buenos Aires (Argentina); CONICET, Avda. Rivadavia 1917(C1033AAJ), Ciudad Autonoma de Buenos Aires (Argentina)] (and others)

    2009-07-15

    In this work we describe the present status of an ongoing project to develop a tandem-electrostatic-quadrupole (TESQ) accelerator facility for accelerator-based (AB) BNCT at the Atomic Energy Commission of Argentina in Buenos Aires. The project final goal is a machine capable of delivering 30 mA of 2.4 MeV protons to be used in conjunction with a neutron production target based on the {sup 7}Li(p,n){sup 7}Be reaction slightly beyond its resonance at 2.25 MeV. These are the specifications needed to produce sufficiently intense and clean epithermal neutron beams, based on the {sup 7}Li(p,n){sup 7}Be reaction, to perform BNCT treatment for deep-seated tumors in less than an hour. An electrostatic machine is the technologically simplest and cheapest solution for optimized AB-BNCT. The machine being designed and constructed is a folded TESQ with a high-voltage terminal at 1.2 MV intended to work in air. Such a machine is conceptually shown to be capable of transporting and accelerating a 30 mA proton beam to 2.4 MeV. The general geometric layout, its associated electrostatic fields, and the acceleration tube are simulated using a 3D finite element procedure. The design and construction of the ESQ modules is discussed and their electrostatic fields are investigated. Beam transport calculations through the accelerator are briefly mentioned. Likewise, work related to neutron production targets, strippers, beam shaping assembly and patient treatment room is briefly described.0.

  4. Determination of cosmogenic Ca-41 in a meteorite with tandem accelerator mass spectrometry

    Science.gov (United States)

    Kubik, P. W.; Elmore, D.; Conard, N. J.; Nishiizumi, K.; Arnold, J. R.

    1986-01-01

    The first use of tandem accelerator mass spectrometry (TAMS) to measure the content of Ca-41 in a natural sample, the iron Bogou meteorite, is reported. Ca in the samples was extracted by hydroxide precipitation and purified by means of a caution exchange resin (AG 50W-X8). After adding 4 percent ammonium oxide, the precipitate was ignited to CaO in a quartz vial at about 1100 C. The Ca-41/Ca ratios were determined following acceleration by alternate measurements of the Ca-40 beam current in an image Faraday cup. Ca-41 particles were also measured using a gas counter. The measured Ca-41/Ca ratio was 3.8 + or -0.6 x 10 to the 12th, which corresponds to a Ca-41 activity of 6.9 + or -1.1 d.p.m. per kg. Calculation of the half-life of Ca-41 in the Bogou meteorite yielded an age of 103,000 years.

  5. German Librarianship and Munich Libraries

    Directory of Open Access Journals (Sweden)

    Osman Ümit Özen

    1994-06-01

    Full Text Available There are 27 municipal libraries including the Central Public Library in Munich. The other important libraries in the city are Bayern State National Library, Maximillian University Library, a technical highschool library and the "Deutsches Musuem" Library. All these libraries are financed locally. The author introduces these libraries briefly and compares German libraries with Turkish libraries. He concludes that although theoretically there are not distinctive differences, in practice, buildings and their layout are better in Germany where more variety of services are offered. In Turkey standardization has not been realized yet. Turkey needs to computerize and network to improve the services offered in an efficient way.

  6. Installation of an injector for SNICS source of the Tandem Accelerator; Instalacion de un Inyector para fuente SNICS del Acelerador Tandem

    Energy Technology Data Exchange (ETDEWEB)

    Villasenor S, P. [ININ, Centro Nuclear Nabor Carrillo (Mexico)]. e-mail: peguvi@nuclear.inin.mx

    2006-07-01

    Presently work, the adaptation and installation of an accelerating tube (that operates as Injector of 75 KV), to the source of ions 'Sputtering Negative Ion Cesium Source', (SNICS), of the Tandem Accelerator EN of the Nuclear Center is presented. This work allowed to increase the acceleration energy from the negative ions to the beginning of the tank. Since the beam energy that it was possible to obtain from the source, it was very below the design parameters, what limited in great measure the reach of the experiments that could be carried out, was urgent to carry out the installation of the accelerator tube mentioned to the source. The limitations in the available resources had impeded this improvement and it took time being deferred. The added value of this adaptation, it resides in that it is a specialized work and it was, finally, carried out with success by the workers of the Accelerator, adapting to the few existent resources and achieving with it a substantial improvement of the bombing currents obtained for the samples of the investigators. (Author)

  7. Comparison of a 250 kV single-stage accelerator mass spectrometer with a 5 MV tandem accelerator mass spectrometer--fitness for purpose in bioanalysis.

    Science.gov (United States)

    Young, G C; Corless, S; Felgate, C C; Colthup, P V

    2008-12-01

    The introduction of 'compact' accelerator mass spectrometers into biomedical science, including use in drug metabolism and bioanalytical applications, is an exciting recent development. Comparisons are presented here between a more established and relatively large tandem accelerator which operates at up to 5 MV and a conventional laboratory-sized 250 kV single-stage accelerator mass spectrometer. Biological samples were enriched with low levels of radiocarbon, then converted into graphite prior to analysis on each of the two instruments. The data obtained showed the single-stage instrument to be capable of delivering comparable results, and thus able to provide similar study support, with that provided by the 5 MV instrument, without the significant overheads and complexities which are inherent to the operation of the larger instrument. We believe that the advent of these laboratory-sized accelerator mass spectrometry (AMS) instruments represents a real turning point in the potential for application of AMS by a wider user group.

  8. AMS of {sup 36}Cl with the VERA 3 MV tandem accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Martschini, Martin, E-mail: martin.martschini@univie.ac.at [University of Vienna, Faculty of Physics - Isotope Research, VERA Laboratory, Waehringer Strasse 17, A-1090 Vienna (Austria); Andersson, Pontus; Forstner, Oliver; Golser, Robin [University of Vienna, Faculty of Physics - Isotope Research, VERA Laboratory, Waehringer Strasse 17, A-1090 Vienna (Austria); Hanstorp, Dag; Lindahl, Anton O. [Department of Physics, University of Gothenburg, SE-412 96 Gothenburg (Sweden); Kutschera, Walter; Pavetich, Stefan; Priller, Alfred [University of Vienna, Faculty of Physics - Isotope Research, VERA Laboratory, Waehringer Strasse 17, A-1090 Vienna (Austria); Rohlen, Johan [Department of Physics, University of Gothenburg, SE-412 96 Gothenburg (Sweden); Steier, Peter [University of Vienna, Faculty of Physics - Isotope Research, VERA Laboratory, Waehringer Strasse 17, A-1090 Vienna (Austria); Suter, Martin [Ion Beam Physics, Department of Physics, ETH Zurich, CH-8093 Zurich (Switzerland); Wallner, Anton [University of Vienna, Faculty of Physics - Isotope Research, VERA Laboratory, Waehringer Strasse 17, A-1090 Vienna (Austria)

    2013-01-15

    Recent progress with compact ionization chambers has opened new possibilities for isobar suppression in accelerator mass spectrometry (AMS). Separation of {sup 36}Cl (t{sub 1/2} = 0.30 Ma) at natural isotopic levels from its stable isobar {sup 36}S became feasible at particle energies of 24 MeV, which are also accessible for medium-sized tandem accelerators with 3 MV terminal voltage like VERA (Vienna Environmental Research Accelerator). Investigations with an ionization chamber revealed how physics favors isobar separation even at energies below the maximum of the Bragg curve. The strong energy focusing effect at high energy losses reduces energy straggling significantly and isobar separation steadily increases up to almost full energy loss. With an optimized detection setup, sulfur suppression factors of 2 Multiplication-Sign 10{sup 4} have been achieved. Refraining from the additional use of degrader foils has the benefit of high transmission to the detector ({approx}16%), but requires a low sulfur output from the ion source. Therefore several backing materials have been screened for sulfur content. The dependence of the sulfur output on the AgCl sample size has been investigated as well. Precision and accuracy have been thoroughly assessed over the last two years. Since drifts in the spectra are efficiently corrected by monitoring the position of the {sup 36}S peak, the reproducibility for high ratio samples ({sup 36}Cl/Cl > 10{sup -12}) is better than 2%. Our blank value of {sup 36}Cl/Cl Almost-Equal-To (5 {+-} 5) Multiplication-Sign 10{sup -16} is competitive to other labs. {sup 36}Cl has become a routine AMS-isotope at VERA. Recently we also explored novel techniques for additional sulfur suppression already in the ion source. While results with a small gas reaction cell in front of the sputter target were discouraging, a decrease in the sulfur/chlorine ratio by one order of magnitude was achieved by directing 300 mW continuous wave laser beam at 445 nm

  9. GERDA test facilities in Munich

    Energy Technology Data Exchange (ETDEWEB)

    Jelen, M.; Abt, I.; Caldwell, A.; Liu Jing; Kroeninger, K.; Lenz, D.; Liu Xiang; Majorovits, B.; Schubert, J. [Max-Planck-Inst. fuer Physik, Muenchen (Germany)

    2007-07-01

    The GERDA (Germanium Detector Array) experiment is designed to search for neutrinoless double-beta decay of {sup 76}Ge. Germanium detectors enriched in {sup 76}Ge will be submerged in pure liquid argon. The cryogenic liquid is used as cooling liquid for the detectors and as shielding against gamma radiation. Several test facilities are currently under construction at the MPI Munich. Prototype Germanium detectors are tested in conditions close to the experimental setup of GERDA. Detector parameters are determined in a specialized vacuum teststand as well as directly in liquid argon. A new vacuum teststand named Galatea is under construction. It will be used to expose germanium detectors to {alpha}- and {beta}-particles and study their response to surface events. This yields information about dead layers and the response to surface contaminations. (orig.)

  10. Calibration in energy of the Tandem Van De Graaff Accelerator; Calibracion en energia del Acelerador Tandem Van De Graaff

    Energy Technology Data Exchange (ETDEWEB)

    Ramirez T, J.J.; Lopez M, J.; Villasenor S, P.; Aspiazu F, J.A.; Linarte B, G.; Garcia R, B. [Instituto Nacional de Investigaciones Nucleares, A.P. 18-1027, 11801 Mexico D.F. (Mexico)

    2002-07-01

    The resonance at E{sub R} = 4.808 {+-} 0.005 MeV in the elastic scattering {sup 12}C (p,p) C{sup 12} was reproduced for determining the new curvature radius of the beam after realignment the acceleration line (r= 102.633 {+-} 0.076 cm) and new tables of energy-frequency for protons and deuterons were made. (Author)

  11. Accelerator tube construction and characterization for a tandem-electrostatic-quadrupole for accelerator-based boron neutron capture therapy

    Energy Technology Data Exchange (ETDEWEB)

    Cartelli, D.; Thatar Vento, V. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica (Argentina)] [CONICET, Av Rivadavia 1917 (1033), Buenos Aires (Argentina); Castell, W. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica (Argentina); Di Paolo, H. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica (Argentina)] [Escuela de Ciencia y Tecnologia, Universidad Nacional de San Martin (Argentina); Kesque, J.M. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica (Argentina); Bergueiro, J. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica (Argentina)] [CONICET, Av Rivadavia 1917 (1033), Buenos Aires (Argentina); Valda, A.A. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica (Argentina)] [Escuela de Ciencia y Tecnologia, Universidad Nacional de San Martin (Argentina)

    2011-12-15

    The accelerator tubes are essential components of the accelerator. Their function is to transport and accelerate a very intense proton or deuteron beam through the machine, from the ion source to the neutron production target, without significant losses. In this contribution, we discuss materials selected for the tube construction, the procedures used for their assembly and the testing performed to meet the stringent requirements to which it is subjected.

  12. GPU accelerated tandem traversal of blocked bounding volume hierarchy collision detection for multibody dynamics

    DEFF Research Database (Denmark)

    Damkjær, Jesper; Erleben, Kenny

    2009-01-01

    hierarchies. Our approach makes it possible to perform non-convex object versus non-convex object collision on the GPU, using tandem traversals of bounding volume hierarchies. Prior work only supports single traversals on GPUs. We introduce a blocked hierarchy data structure, using imaginary nodes...

  13. Alternative uses of a megavolt tandem accelerator for few-keV studies with ion-source SIMS monitoring

    Science.gov (United States)

    Mello, S. L. A.; Codeço, C. F. S.; Magnani, B. F.; Sant'Anna, M. M.

    2016-06-01

    We increase the versatility of a tandem electrostatic accelerator by implementing simple modifications to the standard operation procedure. While keeping its ability to deliver MeV ion beams, we show that the experimental setup can (i) provide good quality ion beams in the few-keV energy range and (ii) be used to study ion-beam surface modification with simultaneous secondary ion mass spectrometry. This latter task is accomplished without using any chamber connected to the accelerator exit. We perform mass spectrometry of the few-keV anions produced in the ion source by measuring their neutral counterparts at the accelerator exit with energies up to 1.7 MeV. With an additional modification, a high-current few-keV regime is obtained, using the ion source as an irradiation chamber and the accelerator itself only as a mass spectrometer. As an example of application, we prepare a sample for the study of ion-beam assisted dewetting of a thin Au film on a Si substrate.

  14. The Munich Parasomnia Screening in Psychiatry

    NARCIS (Netherlands)

    Bosch, M.P.C.; Luijtelaar, E.L.J.M. van; Noort, M.W.M.L. van den; Groetelaers, L.; Lim, S.; Egger, J.I.M.; Coenen, A.M.L.

    2012-01-01

    Background The aim was to investigate the subjective experience of parasomnias and other nocturnal behaviors in depression and schizophrenia. Materials and methods Using the Munich Parasomnia Screening (MUPS), 21 parasomnias and other nocturnal behaviors were assessed in 85 participants; 27 were pat

  15. The Munich Parasomnia Screening in Psychiatry

    NARCIS (Netherlands)

    Bosch, M.P.C.; Luijtelaar, E.L.J.M. van; Noort, M.W.M.L. van den; Groetelaers, L.; Lim, S.; Egger, J.I.M.; Coenen, A.M.L.

    2012-01-01

    Background The aim was to investigate the subjective experience of parasomnias and other nocturnal behaviors in depression and schizophrenia. Materials and methods Using the Munich Parasomnia Screening (MUPS), 21 parasomnias and other nocturnal behaviors were assessed in 85 participants; 27 were

  16. C-14 content of ten meteorites measured by tandem accelerator mass spectrometry

    Science.gov (United States)

    Brown, R. M.; Andrews, H. R.; Ball, G. C.; Burn, N.; Imahori, Y.; Milton, J. C. D.; Fireman, E. L.

    1984-01-01

    Measurements of C-14 in three North American and seven Antarctic meteorites show in most cases that this cosmogenic isotope, which is tightly bound, was separated from absorbed atmospheric radiocarbon by stepwise heating extractions. The present upper limit to age determination by the accelerator method varies from 50,000 to 70,000 years, depending on the mass and carbon content of the sample. The natural limit caused by cosmic ray production of C-14 in silicate rocks at 2000 m elevation is estimated to be 55,000 + or - 5000 years. An estimation is also made of the 'weathering ages' of the Antarctic meteorites from the specific activity of loosely bound CO2 which is thought to be absorbed from the terrestrial atmosphere. Accelerator measurements are found to agree with previous low level counting measurements, but are more sensitive and precise.

  17. Reactor atómico. Munich

    Directory of Open Access Journals (Sweden)

    Weber, Gerhard

    1959-03-01

    Full Text Available Una vez más el espíritu alemán ha quedado definido por su gran capacidad para la iniciación de empresas duras y difíciles con la construcción de esta estación atómica, creada para corresponder a las necesidades del Instituto de Física en la Escuela Superior Técnica de Munich.

  18. A Tandem Repeat in Decay Accelerating Factor 1 Is Associated with Severity of Murine Mercury-Induced Autoimmunity

    Directory of Open Access Journals (Sweden)

    David M. Cauvi

    2014-01-01

    Full Text Available Decay accelerating factor (DAF, a complement-regulatory protein, protects cells from bystander complement-mediated lysis and negatively regulates T cells. Reduced expression of DAF occurs in several systemic autoimmune diseases including systemic lupus erythematosus, and DAF deficiency exacerbates disease in several autoimmune models, including murine mercury-induced autoimmunity (mHgIA. Daf1, located within Hmr1, a chromosome 1 locus associated in DBA/2 mice with resistance to mHgIA, could be a candidate. Here we show that reduced Daf1 transcription in lupus-prone mice was not associated with a reduction in the Daf1 transcription factor SP1. Studies of NZB mice congenic for the mHgIA-resistant DBA/2 Hmr1 locus suggested that Daf1 expression was controlled by the host genome and not the Hmr1 locus. A unique pentanucleotide repeat variant in the second intron of Daf1 in DBA/2 mice was identified and shown in F2 intercrosses to be associated with less severe disease; however, analysis of Hmr1 congenics indicated that this most likely reflected the presence of autoimmunity-predisposing genetic variants within the Hmr1 locus or that Daf1 expression is mediated by the tandem repeat in epistasis with other genetic variants present in autoimmune-prone mice. These studies argue that the effect of DAF on autoimmunity is complex and may require multiple genetic elements.

  19. Mimosoid legume plastome evolution: IR expansion, tandem repeat expansions, and accelerated rate of evolution in clpP

    Science.gov (United States)

    Dugas, Diana V.; Hernandez, David; Koenen, Erik J.M.; Schwarz, Erika; Straub, Shannon; Hughes, Colin E.; Jansen, Robert K.; Nageswara-Rao, Madhugiri; Staats, Martijn; Trujillo, Joshua T.; Hajrah, Nahid H.; Alharbi, Njud S.; Al-Malki, Abdulrahman L.; Sabir, Jamal S. M.; Bailey, C. Donovan

    2015-01-01

    The Leguminosae has emerged as a model for studying angiosperm plastome evolution because of its striking diversity of structural rearrangements and sequence variation. However, most of what is known about legume plastomes comes from few genera representing a subset of lineages in subfamily Papilionoideae. We investigate plastome evolution in subfamily Mimosoideae based on two newly sequenced plastomes (Inga and Leucaena) and two recently published plastomes (Acacia and Prosopis), and discuss the results in the context of other legume and rosid plastid genomes. Mimosoid plastomes have a typical angiosperm gene content and general organization as well as a generally slow rate of protein coding gene evolution, but they are the largest known among legumes. The increased length results from tandem repeat expansions and an unusual 13 kb IR-SSC boundary shift in Acacia and Inga. Mimosoid plastomes harbor additional interesting features, including loss of clpP intron1 in Inga, accelerated rates of evolution in clpP for Acacia and Inga, and dN/dS ratios consistent with neutral and positive selection for several genes. These new plastomes and results provide important resources for legume comparative genomics, plant breeding, and plastid genetic engineering, while shedding further light on the complexity of plastome evolution in legumes and angiosperms. PMID:26592928

  20. Biological Effects of Particles with Very High Energy Deposition on Mammalian Cells Utilizing the Brookhaven Tandem Van de Graaff Accelerator

    Science.gov (United States)

    Saha, Janapriya; Cucinotta, Francis A.; Wang, Minli

    2013-01-01

    High LET radiation from GCR (Galactic Cosmic Rays) consisting mainly of high charge and energy (HZE) nuclei and secondary protons and neutrons, and secondaries from protons in SPE (Solar Particle Event) pose a major health risk to astronauts due to induction of DNA damage and oxidative stress. Experiments with high energy particles mimicking the space environment for estimation of radiation risk are being performed at NASA Space Radiation Laboratory at BNL. Experiments with low energy particles comparing to high energy particles of similar LET are of interest for investigation of the role of track structure on biological effects. For this purpose, we report results utilizing the Tandem Van de Graaff accelerator at BNL. The primary objective of our studies is to elucidate the influence of high vs low energy deposition on track structure, delta ray contribution and resulting biological responses. These low energy ions are of special relevance as these energies may occur following absorption through the spacecraft and shielding materials in human tissues and nuclear fragments produced in tissues by high energy protons and neutrons. This study will help to verify the efficiency of these low energy particles and better understand how various cell types respond to them.

  1. Fast parallel tandem mass spectral library searching using GPU hardware acceleration.

    Science.gov (United States)

    Baumgardner, Lydia Ashleigh; Shanmugam, Avinash Kumar; Lam, Henry; Eng, Jimmy K; Martin, Daniel B

    2011-06-03

    Mass spectrometry-based proteomics is a maturing discipline of biologic research that is experiencing substantial growth. Instrumentation has steadily improved over time with the advent of faster and more sensitive instruments collecting ever larger data files. Consequently, the computational process of matching a peptide fragmentation pattern to its sequence, traditionally accomplished by sequence database searching and more recently also by spectral library searching, has become a bottleneck in many mass spectrometry experiments. In both of these methods, the main rate-limiting step is the comparison of an acquired spectrum with all potential matches from a spectral library or sequence database. This is a highly parallelizable process because the core computational element can be represented as a simple but arithmetically intense multiplication of two vectors. In this paper, we present a proof of concept project taking advantage of the massively parallel computing available on graphics processing units (GPUs) to distribute and accelerate the process of spectral assignment using spectral library searching. This program, which we have named FastPaSS (for Fast Parallelized Spectral Searching), is implemented in CUDA (Compute Unified Device Architecture) from NVIDIA, which allows direct access to the processors in an NVIDIA GPU. Our efforts demonstrate the feasibility of GPU computing for spectral assignment, through implementation of the validated spectral searching algorithm SpectraST in the CUDA environment.

  2. Lithium antineutrino source in the tandem scheme of the accelerator and neutron producting tungsten target

    CERN Document Server

    Lyashuk, V I

    2016-01-01

    The antineutrinos of the neutron rich 8Li isotope is characterized by hard and good defined spectrum - averaged energy is 6.5 MeV and maximal - up to 13 MeV. An intensive antineutrino source with such parameters can be unique instrument for neutrino investigations and especially for search of sterile neutrinos. The 8Li can be produced by (n,gamma)-activation of 7Li isotope. The proposed scheme of the antineutrino source is based on the lithium blanket around the accelerator neutron producting target. We propose to use heavy water solution of the lithium hydroxide instead of lithium in metallic state. Such solution for lithium blanket substance ensure the large perspectives in real steps for creation of this installation. An analyses of neutron fields in the blanket and distribution of 8Li creation allows to propose the next principal steps in the construction of the lithium blanket. We propose to enclose the blanket volume isolating it's central part with more high 8Li production. This solution allows to decr...

  3. European waste-to-energy systems. Case study of Munich: Munich North IA and IB, Munich North II, Munich South IV and V

    Energy Technology Data Exchange (ETDEWEB)

    None

    1977-05-01

    The city of Munich has a population of 1,315,000. Solid waste is collected by a city department and delivered to the city's own Electricity Works. The Electricity Works incinerates the waste in five incinerators in two separate locations (the North and South plants). Munich's five incinerators represent three different designs for co-generation of heat and electrical energy. All burn both waste and fossil fuel and all use Benson boilers to produce steam at 184 bars (181.5 atm) and 540/sup 0/C (1,000/sup 0/F). The Electricity Works recovers energy in the form of electricity, hot water, and steam. Ash, bulky objects, and non-incinerable waste are dumped on a ''garbage mountain'' within the city limits. The system's priority is to produce electricity for the city grid rather than to treat waste. The hot water and steam produced are used in district heating. The system is peakloaded both for electricity and for district heating, and, as a result, is operated with some diseconomy. Over 450,000 metric tons (495,700 short tons) of waste were burned in 1975. That amount represents practically all the solid waste collected in Munich. A shredder with a capacity of 30,000 metric tons (33,000 short tons) per year will be added in 1977 and this will allow for even more complete incineration in the future. Some fees for collection go towards the difference between the total costs ofincineration and the revenue earned from the sale of energy and scrap metal. The rates charged appear to be far below actual costs of incineration, which suggests that the sale of electricity is subsidizing the cost of incineration.

  4. Development of high intensity ion sources for a Tandem-Electrostatic-Quadrupole facility for Accelerator-Based Boron Neutron Capture Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Bergueiro, J. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica (Argentina)] [CONICET, Buenos Aires (Argentina); Igarzabal, M.; Suarez Sandin, J.C. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica (Argentina); Somacal, H.R. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica (Argentina)] [Escuela de Ciencia y Tecnologia, Universidad Nacional de San Martin (Argentina); Thatar Vento, V. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica (Argentina)] [CONICET, Buenos Aires (Argentina); Huck, H.; Valda, A.A. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica (Argentina)] [Escuela de Ciencia y Tecnologia, Universidad Nacional de San Martin (Argentina); Repetto, M. [Gerencia de Investigacion y Aplicaciones, Comision Nacional de Energia Atomica (Argentina)

    2011-12-15

    Several ion sources have been developed and an ion source test stand has been mounted for the first stage of a Tandem-Electrostatic-Quadrupole facility For Accelerator-Based Boron Neutron Capture Therapy. A first source, designed, fabricated and tested is a dual chamber, filament driven and magnetically compressed volume plasma proton ion source. A 4 mA beam has been accelerated and transported into the suppressed Faraday cup. Extensive simulations of the sources have been performed using both 2D and 3D self-consistent codes.

  5. The new external ion beam analysis setup at the Demokritos Tandem accelerator and first applications in cultural heritage

    Science.gov (United States)

    Sokaras, Dimosthenis; Bistekos, Euthimios; Georgiou, Lambros; Salomon, Joseph; Bogovac, Mladen; Aloupi-Siotis, Eleni; Paschalis, Vasilis; Aslani, Ioanna; Karabagia, Sofia; Lagoyannis, Anastasios; Harissopulos, Sotirios; Kantarelou, Vasiliki; Karydas, Andreas-Germanos

    2011-03-01

    At the 5.5 MV Tandem VdG accelerator of the Institute of Nuclear Physics of N.C.S.R. "Demokritos", Athens, Greece, an external ion-beam set-up has been recently developed and installed. The aim of this development was to integrate the analytical capabilities of the PIXE, RBS and PIGE ion beam techniques in one experimental set-up, so that to attain a complete elemental and near surface structural characterization of samples in an almost non-destructive way and without any limitation concerning their size or conductive state. A careful 3D mechanical drawing optimized the set-up experimental parameters achieving probe dimensions at the millimeter range (1 mm 2) and fulfilling the special requirements imposed for optimum performance of the aforementioned techniques, including the possibility to use heavier, than protons, ion beams. For the digital pulse processing of the X-ray, γ-ray and charged particle detector signals, novel hardware and software tools were developed based on a custom FPGA configuration. The first applications were focused in the quality control of materials that have been intentionally contaminated with a particular tracer-element ("tagged" materials). The tagged materials which were developed and tested are technologically authentic replicas of ancient attic ceramics with black glazed decoration. Analytical diagnostic studies were carried out for a few representative paintings of contemporary Greek painters in order to identify and document materials/pigments and techniques and eventually to prevent trade of fakes. Finally, ancient glass beads were also examined with respect to the sodium concentration and its in-depth homogeneity.

  6. The new external ion beam analysis setup at the Demokritos Tandem accelerator and first applications in cultural heritage

    Energy Technology Data Exchange (ETDEWEB)

    Sokaras, Dimosthenis, E-mail: dsokaras@inp.demokritos.g [Institute of Nuclear Physics, N.C.S.R. ' Demokritos' , Aghia Paraskevi, 15310 Athens (Greece); Bistekos, Euthimios; Georgiou, Lambros [Philon Models, 18541 Piraeus (Greece); Salomon, Joseph [Laboratoire du C2RMF, Centre de Rechereche et de Restauration des Musees du France, 75001 Paris (France); Bogovac, Mladen [Institute Ruder Boskovic, 10002 Zagreb (Croatia); Aloupi-Siotis, Eleni [Thetis Authentics Ltd., 11636 Athens (Greece); Paschalis, Vasilis [Benaki Museum, 10674 Athens (Greece); Aslani, Ioanna [Thetis Authentics Ltd., 11636 Athens (Greece); Karabagia, Sofia; Lagoyannis, Anastasios; Harissopulos, Sotirios; Kantarelou, Vasiliki [Institute of Nuclear Physics, N.C.S.R. ' Demokritos' , Aghia Paraskevi, 15310 Athens (Greece); Karydas, Andreas-Germanos [Institute of Nuclear Physics, N.C.S.R. ' Demokritos' , Aghia Paraskevi, 15310 Athens (Greece); Nuclear Spectrometry and Applications Laboratory, International Atomic Energy Agency (IAEA), 2444 Seibersdorf (Austria)

    2011-03-01

    At the 5.5 MV Tandem VdG accelerator of the Institute of Nuclear Physics of N.C.S.R. 'Demokritos', Athens, Greece, an external ion-beam set-up has been recently developed and installed. The aim of this development was to integrate the analytical capabilities of the PIXE, RBS and PIGE ion beam techniques in one experimental set-up, so that to attain a complete elemental and near surface structural characterization of samples in an almost non-destructive way and without any limitation concerning their size or conductive state. A careful 3D mechanical drawing optimized the set-up experimental parameters achieving probe dimensions at the millimeter range (1 mm{sup 2}) and fulfilling the special requirements imposed for optimum performance of the aforementioned techniques, including the possibility to use heavier, than protons, ion beams. For the digital pulse processing of the X-ray, {gamma}-ray and charged particle detector signals, novel hardware and software tools were developed based on a custom FPGA configuration. The first applications were focused in the quality control of materials that have been intentionally contaminated with a particular tracer-element ('tagged' materials). The tagged materials which were developed and tested are technologically authentic replicas of ancient attic ceramics with black glazed decoration. Analytical diagnostic studies were carried out for a few representative paintings of contemporary Greek painters in order to identify and document materials/pigments and techniques and eventually to prevent trade of fakes. Finally, ancient glass beads were also examined with respect to the sodium concentration and its in-depth homogeneity.

  7. "Connecting the Dots": Munich, Iraq, and the Lessons of History

    Science.gov (United States)

    Conolly-Smith, Peter

    2009-01-01

    This paper seeks to explore the ways in which "lessons of history," in particular the "Munich analogy," have been misconstrued in justification of United States armed intervention since the beginning of the Cold War. While the wisdom of a hawkish foreign policy is indeed one lesson of Munich--certainly as applied to World War…

  8. Morphine brain pharmacokinetics at very low concentrations studied with accelerator mass spectrometry and liquid chromatography-tandem mass spectrometry.

    Science.gov (United States)

    Sadiq, Muhammad Waqas; Salehpour, Mehran; Forsgard, Niklas; Possnert, Göran; Hammarlund-Udenaes, Margareta

    2011-02-01

    Morphine has been predicted to show nonlinear blood-brain barrier transport at lower concentrations. In this study, we investigated the possibility of separating active influx of morphine from its efflux by using very low morphine concentrations and compared accelerator mass spectrometry (AMS) with liquid chromatography-tandem mass spectrometry (LC-MS/MS) as a method for analyzing microdialysis samples. A 10-min bolus infusion of morphine, followed by a constant-rate infusion, was given to male rats (n = 6) to achieve high (250 ng/ml), medium (50 ng/ml), and low (10 ng/ml) steady-state plasma concentrations. An additional rat received infusions to achieve low (10 ng/ml), very low (2 ng/ml), and ultralow (0.4 ng/ml) concentrations. Unbound morphine concentrations from brain extracellular fluid and blood were sampled by microdialysis and analyzed by LC-MS/MS and AMS. The average partition coefficient for unbound drug (K(p,uu)) values for the low and medium steady-state levels were 0.22 ± 0.08 and 0.21 ± 0.05, respectively, when measured by AMS [not significant (NS); p = 0.5]. For the medium and high steady-state levels, K(p,uu) values were 0.24 ± 0.05 and 0.26 ± 0.05, respectively, when measured by LC-MS/MS (NS; p = 0.2). For the low, very low, and ultralow steady-state levels, K(p,uu) values were 0.16 ± 0.01, 0.16 ± 0.02, and 0.18 ± 0.03, respectively, when measured by AMS. The medium-concentration K(p,uu) values were, on average, 16% lower when measured by AMS than by LC-MS/MS. There were no significant changes in K(p,uu) over a 625-fold concentration range (0.4-250 ng/ml). It was not possible to separate active uptake transport from active efflux using these low concentrations. The two analytical methods provided indistinguishable results for plasma concentrations but differed by up to 38% for microdialysis samples; however, this difference did not affect our conclusions.

  9. Major Conference about Astronomical Technology in Munich

    Science.gov (United States)

    2000-03-01

    Press Conference on Monday, March 27, 2000 Which are the latest astronomical discoveries made with the new 8-10 metre class astronomical telescopes? Will it be possible to construct even more powerful instruments on the ground and in space to explore the near and distant Universe at all wavelengths from gamma-rays to radio waves? Which research areas in this dynamical science are likely to achieve break-throughs with emerging new technologies? These are some of the central themes that will be discussed by more than 600 specialists from all over the world at an international conference in Munich (Germany), "Astronomical Telescopes and Instruments 2000" , beginning on Monday, March 27, 2000. During five days, the modern architecture of the new International Congress Center in the Bavarian capital will be the scene of lively exchanges about recent progress at the world's top-class astronomical research facilities and the presentation of inspired new ideas about future technological opportunities. The conference will be accompanied by numerous on-site exhibition stands by the major industries and research organisations in this wide field. This meeting is the latest in a series, organised every second year, alternatively in the USA and Europe by the International Society for Optical Engineering (SPIE) , this year with the European Southern Observatory (ESO) as co-sponsor and host institution. The conference will be opened in the morning of March 27 by the Bavarian Minister of Science, Research and Arts, Hans Zehetmair . His address will be followed by keynote speeches by Massimo Tarenghi (European Southern Observatory), James B. Breckenridge (National Science Foundation, USA), Harvey Butcher (Netherlands Foundation for Research in Astronomy) and Albrecht Ruediger (Max Planck Institut für Quantenoptik, Germany). The conference is subtitled "Power Telescopes and Instrumentation into the New Millennium" and will be attended by leading scientists and engineers from all

  10. Haptic information provided by the "anchor system" reduces trunk sway acceleration in the frontal plane during tandem walking in older adults.

    Science.gov (United States)

    Costa, Andréia Abud da Silva; Manciopi, Priscila Abbári Rossi; Mauerberg-deCastro, Eliane; Moraes, Renato

    2015-11-16

    This study assessed whether the use of an "anchor system" benefited older adults who performed a tandem walking task. Additionally, we tested the effects of practice with the anchor system during walking on trunk stability, in the frontal plane, of older adults. Forty-four older adults were randomly assigned to three groups: control group, 0g anchor group, and 125g anchor group. Individuals in each group performed a tandem walking task on the GaitRite system with an accelerometer placed on the cervical region. The participants in the 125g anchor group held, in each hand, a flexible cable with a light mass attached at the end of the cable, which rested on the ground. While the participants walked, they pulled on the cables just enough to keep them taut as the masses slid over the ground. The 0g anchor group held an anchor tool without any mass attached to the end portion. The results of this study demonstrated that the use of the anchor system contributed to the reduction of trunk acceleration in the frontal plane. However, this effect did not persist after removal of the anchors, which suggests that the amount of practice with this tool was insufficient to generate any lasting effect, or that the task was not sufficiently challenging, or both.

  11. Screening and identification of unknown contaminants in water with liquid chromatography and quadrupole-orthogonal acceleration-time-of-flight tandem mass spectrometry.

    Science.gov (United States)

    Bobeldijk, I; Vissers, J P; Kearney, G; Major, H; Van Leerdam, J A

    2001-09-21

    In order to assess and maintain the quality of surface waters, target compound monitoring is often not sufficient. Many unknown micro-contaminants are present in water, originating in municipal, industrial or agricultural effluents. Some of these might pose a risk to drinking water production and consequently to human health. The possibilities of screening surface water and identification of these non-target water pollutants with modern data acquisition possibilities of hybrid quadrupole-orthogonal acceleration time of flight mass spectrometers (Q-TOF), such as data-dependent MS to MS/MS switching were investigated. Using model compounds, a procedure for the liquid chromatography-tandem mass spectrometry (LC-MS/MS) screening of water extracts was developed, enabling the detection and identification of compounds at levels < or = 0.25 microg/l in surface water. Based on the accurate mass the elemental compositions for the precursor and product ions are calculated. The calculated chemical formulae are searched against the Merck index, the NIST library, an own database containing about 2,500 water pollutants (pesticides and other contaminants) as well as a CI-CID library containing tandem MS spectra of about 100 water contaminants. The developed approach was applied for the identification of unknown compounds, present in native surface water extract. For three of these compounds, structures were proposed. Confirmation of the proposed structures with standards was beyond the scope of this study.

  12. Tandem-Accelerator Mass-Spectrometry Measurements of 36Cl, 129I and Osmium Isotopes in Diverse Natural Samples

    Science.gov (United States)

    Gove, H. E.

    1987-08-01

    Tandem AMS measurements at Rochester in the past few years have mainly involved the radioisotopes 36Cl and 129I, and some work on 10Be, in a variety of terrestrial and extraterrestrial samples. Some measurements have also been made on certain stable isotopes of osmium in meteorites and geological samples from impact craters. Measurements of 36Cl have been made in groundwater and surface rocks for dating purposes, in ice and soil samples containing nuclear-weapon testing fallout for tracing water movement, and in meteorites and Antarctic ice for terrestrial and extraterrestrial meteoritic age determination. Also, 10Be has been measured in a lake sediment, and 36Cl in Greenland ice, through the period of the Maunder minimum; 129I has been measured in hydrological systems, in petroleum and in hydrothermal convection cells in the oceanic crust. Other applications involving measurements of these two radioisotopes include hydrothermal fluids associated with gold mineralization and the determination of the integrity of possible sites for deep nuclear-waste disposal. Previously, the Rochester tandem was employed to measure 14C and isotopes of platinum and iridium in natural samples.

  13. Sanatorio para la infancia, en Munich

    Directory of Open Access Journals (Sweden)

    Haind, Friedrich F.

    1964-10-01

    Full Text Available The main objects to be met in the design this Children's Building were to provide suitable control and protection of the children, adequate working conditions for the nurses, and develop a pleasant family environment. This clinic is an extension of that run by the Sisters of Saint Benedict in Lechnerstrasse, Munich. It consists of two blocks, of 4 and 5 floor levels. It has a semibasement, housing the services, and some spare rooms and other facilities, described in the enclosed plans. The ground floor provides room for 25 beds, for the older boys. On the second floor there are 30 beds for those recently born, whilst the third floor has space for 30 beds for prematurely born babies. The nurses live in the attic, where there are 15 bedrooms, each with two beds, a kitchen and suitable auxiliary facilities. Much thought has been given to the design of details, the general distribution and circulation system has been planned with much care, and the overall functional efficiency of the building as a children's clinic has been kept a paramount factor. All this makes this building an outstanding one among those of this type.Los objetivos principales perseguidos aquí son: conseguir una eficaz vigilancia y protección de los niños; organizar los puestos de trabajo de las enfermeras para que resulten prácticos y agradables, y crear un ambiente familiar La clínica construida —como ampliación de las instalaciones que las Hermanas de San Benito poseen en la calle Lachner, en Munich— comprende dos cuerpos de edificio unidos, de 4 y 5 plantas de altura, respectivamente, y está distribuida del siguiente modo: el semisótano aloja, además de la zona de servicios, una serie de dependencias, que vienen descritas en la respectiva documentación gráfica. La planta baja alberga 25 camas; está destinada a los niños mayores y colegiales; la planta primera, con 30 camas, a los recién nacidos, y la planta segunda, con 30 camas, a la sección de prematuros

  14. Ihr Ticket fur Munchen (Your Ticket to Munich).

    Science.gov (United States)

    Singer, Debbie

    Texts accompanied by photographs and drawings introduce students to four means of public transportation and to major tourist attractions in Munich, German Federal Republic. Vocabulary is glossed in the margin, and texts are followed by questions and exercises. Some suggestions for additional activities are given in English. An appendix includes…

  15. Epigenetics Europe conference. Munich, Germany, 8-9 September 2011.

    Science.gov (United States)

    Jeltsch, Albert

    2011-12-01

    At the Epigenetics Europe conference in Munich, Germany, held on 8-9 September 2011, 19 speakers from different European countries were presenting novel data and concepts on molecular epigenetics. The talks were mainly focused on questions of the generation, maintenance, flexibility and erasure of DNA methylation patterns in context of other epigenetic signals like histone tail modifications and ncRNAs.

  16. Instituto de bioquímica Munich - Alemania Federal

    Directory of Open Access Journals (Sweden)

    Beckert, -

    1975-05-01

    Full Text Available This building, situated in Martinsried, Munich, was awarded the first prize in an international contest. It consists of 15 departments, basically meant for education and research. The complex occupies a large ground, with extensive green zones and covered passages that connect the different blocks, all of them very low: class rooms, testing rooms, electronic microscopy, library, social centre, restaurant auditorium, housing, etc.Este edificio, situado en Martinsried, Munich, fue seleccionado, con el primer premio, en un concurso internacional convocado al efecto. Comprende 15 departamentos destinados, fundamentalmente, a la enseñanza e investigación. El conjunto ocupa una amplia parcela, con profusión de zonas verdes y pasos cubiertos que enlazan los diferentes bloques, todos ellos de poca altura: clases, salas de ensayos, microscopía electrónica, biblioteca, centro social, restaurante, salón de actos, viviendas, etcétera.

  17. History of the Munich-Maisach-Fürstenfeldbruck Geomagnetic Observatory

    Science.gov (United States)

    Soffel, H. C.

    2015-07-01

    The Munich-Maisach-Fürstenfeldbruck Geomagnetic Observatory is one of the observatories with the longest recordings of the geomagnetic field. It started with hourly measurements on 1 August 1840. The founder of the observatory in Munich was Johann von Lamont (1805-1879), the Director of the Royal Bavarian Astronomical Observatory. He had been stimulated to build his own observatory by the initiative of the Göttingen Magnetic Union founded in 1834 by Alexander von Humboldt (1769-1859) and Carl Friedrich Gauss (1777-1855). Before 1840 fewer than five observatories existed; the most prominent ones were those in London and Paris. At the beginning Lamont used equipment delivered by Gauss in Göttingen, but soon started to build instruments of his own design. Among them was a nonmagnetic theodolite which allowed precise geomagnetic measurements to be made also in the field. During the 1850s Lamont carried out geomagnetic surveys and produced geomagnetic maps for Germany and many other European countries. At the end of the nineteenth century accurate geomagnetic measurements in Munich became more and more disturbed by the magnetic stray fields from electric tramways and industry. During this period the quality of the data suffered and the measurements had to be interrupted several times. After a provisional solution in Maisach, a village 25 km west of Munich, a final solution could be found in the vicinity of the nearby city of Fürstenfeldbruck. Here the measurements started again on 1 January 1939. Since the 1980s the observatory has been part of INTERMAGNET, an organization providing almost real-time geomagnetic data of the highest quality.

  18. Lifestyles and Preferences for (Public) Goods: Professional Football in Munich

    OpenAIRE

    Gabriel M. Ahlfeldt; Maennig, Wolfgang; Ölschläger, Michaela

    2009-01-01

    This paper investigates the 2001 referendum on the Allianz-Arena, a professional soccer stadium in Munich, Germany, with respect to lifestyle-specific voter preferences. Using political party affiliation and milieu probabilities as proxy variables, we find that lifestyle-specific preferences, values and attitudes more significantly contribute to the explanation of voting outcome compared to traditional strata-orientated indicators of economic wealth. Thus, lifestyle, preferences, tastes and a...

  19. Tandem Van de Graaff facility

    Data.gov (United States)

    Federal Laboratory Consortium — Completed in 1970, the Tandem Van de Graaff facility was for many years the world's largest electrostatic accelerator facility. It can provide researchers with beams...

  20. Use of an intravenous microdose of 14C-labeled drug and accelerator mass spectrometry to measure absolute oral bioavailability in dogs; cross-comparison of assay methods by accelerator mass spectrometry and liquid chromatography-tandem mass spectrometry.

    Science.gov (United States)

    Miyaji, Yoshihiro; Ishizuka, Tomoko; Kawai, Kenji; Hamabe, Yoshimi; Miyaoka, Teiji; Oh-hara, Toshinari; Ikeda, Toshihiko; Kurihara, Atsushi

    2009-01-01

    A technique utilizing simultaneous intravenous microdosing of (14)C-labeled drug with oral dosing of non-labeled drug for measurement of absolute bioavailability was evaluated using R-142086 in male dogs. Plasma concentrations of R-142086 were measured by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and those of (14)C-R-142086 were measured by accelerator mass spectrometry (AMS). The absence of metabolites in the plasma and urine was confirmed by a single radioactive peak of the parent compound in the chromatogram after intravenous microdosing of (14)C-R-142086 (1.5 microg/kg). Although plasma concentrations of R-142086 determined by LC-MS/MS were approximately 20% higher than those of (14)C-R-142086 as determined by AMS, there was excellent correlation (r=0.994) between both concentrations after intravenous dosing of (14)C-R-142086 (0.3 mg/kg). The oral bioavailability of R-142086 at 1 mg/kg obtained by simultaneous intravenous microdosing of (14)C-R-142086 was 16.1%, this being slightly higher than the value (12.5%) obtained by separate intravenous dosing of R-142086 (0.3 mg/kg). In conclusion, on utilizing simultaneous intravenous microdosing of (14)C-labeled drug in conjunction with AMS analysis, absolute bioavailability could be approximately measured in dogs, but without total accuracy. Bioavailability in humans may possibly be approximately measured at an earlier stage and at a lower cost.

  1. Analysis of intracellular and extracellular microcystin variants in sediments and pore waters by accelerated solvent extraction and high performance liquid chromatography-tandem mass spectrometry.

    Science.gov (United States)

    Zastepa, Arthur; Pick, Frances R; Blais, Jules M; Saleem, Ammar

    2015-05-04

    The fate and persistence of microcystin cyanotoxins in aquatic ecosystems remains poorly understood in part due to the lack of analytical methods for microcystins in sediments. Existing methods have been limited to the extraction of a few extracellular microcystins of similar chemistry. We developed a single analytical method, consisting of accelerated solvent extraction, hydrophilic-lipophilic balance solid phase extraction, and reversed phase high performance liquid chromatography-tandem mass spectrometry, suitable for the extraction and quantitation of both intracellular and extracellular cyanotoxins in sediments as well as pore waters. Recoveries of nine microcystins, representing the chemical diversity of microcystins, and nodularin (a marine analogue) ranged between 75 and 98% with one, microcystin-RR (MC-RR), at 50%. Chromatographic separation of these analytes was achieved within 7.5 min and the method detection limits were between 1.1 and 2.5 ng g(-1) dry weight (dw). The robustness of the method was demonstrated on sediment cores collected from seven Canadian lakes of diverse geography and trophic states. Individual microcystin variants reached a maximum concentration of 829 ng g(-1) dw on sediment particles and 132 ng mL(-1) in pore waters and could be detected in sediments as deep as 41 cm (>100 years in age). MC-LR, -RR, and -LA were more often detected while MC-YR, -LY, -LF, and -LW were less common. The analytical method enabled us to estimate sediment-pore water distribution coefficients (K(d)), MC-RR had the highest affinity for sediment particles (log K(d)=1.3) while MC-LA had the lowest affinity (log K(d)=-0.4), partitioning mainly into pore waters. Our findings confirm that sediments serve as a reservoir for microcystins but suggest that some variants may diffuse into overlying water thereby constituting a new route of exposure following the dissipation of toxic blooms. The method is well suited to determine the fate and persistence of different

  2. Analysis of intracellular and extracellular microcystin variants in sediments and pore waters by accelerated solvent extraction and high performance liquid chromatography-tandem mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Zastepa, Arthur, E-mail: arthur.zastepa@gmail.com; Pick, Frances R.; Blais, Jules M.; Saleem, Ammar

    2015-05-04

    Highlights: • First analytical method for intracellular microcystins (MCs) in sediment. • Includes a suite of variants (LR, {sup 7dm}LR, RR, YR, WR, LA, LF, LY, LW) and nodularin. • Reports the first measurements of MCs in sediment pore waters. • MCs detected in >100 year old lake sediments suggesting long-term preservation. • Sediment-pore water distribution (K{sub d}) differed between variants suggesting differences in environmental fate. - Abstract: The fate and persistence of microcystin cyanotoxins in aquatic ecosystems remains poorly understood in part due to the lack of analytical methods for microcystins in sediments. Existing methods have been limited to the extraction of a few extracellular microcystins of similar chemistry. We developed a single analytical method, consisting of accelerated solvent extraction, hydrophilic–lipophilic balance solid phase extraction, and reversed phase high performance liquid chromatography-tandem mass spectrometry, suitable for the extraction and quantitation of both intracellular and extracellular cyanotoxins in sediments as well as pore waters. Recoveries of nine microcystins, representing the chemical diversity of microcystins, and nodularin (a marine analogue) ranged between 75 and 98% with one, microcystin-RR (MC-RR), at 50%. Chromatographic separation of these analytes was achieved within 7.5 min and the method detection limits were between 1.1 and 2.5 ng g{sup −1} dry weight (dw). The robustness of the method was demonstrated on sediment cores collected from seven Canadian lakes of diverse geography and trophic states. Individual microcystin variants reached a maximum concentration of 829 ng g{sup −1} dw on sediment particles and 132 ng mL{sup −1} in pore waters and could be detected in sediments as deep as 41 cm (>100 years in age). MC-LR, -RR, and -LA were more often detected while MC-YR, -LY, -LF, and -LW were less common. The analytical method enabled us to estimate sediment-pore water

  3. A multi-family residential building, Munich, Germany

    Energy Technology Data Exchange (ETDEWEB)

    Erhorn, H. [Fraunhofer Inst., fuer Bauphysik, Stuttgart (Germany)

    1999-07-01

    This multi-family residential building in the inner city area of Munich is characterized by a compact architectural design and a high standard of thermal insulation. Three of the duplex flats, located on the fifth and sixth floors, have solar air systems, two with transparent insulation systems and one with a solar water system. To reduce the heating energy consumption, three of these flats are provided with solar air systems, two with transparent insulation systems and one with a solar- water system. In the first solar air system, the heated air is lead directly into the apartment. In the second, the air flows through a closed door, releasing the heat to the storage wall. The third system is a combination of both. (author)

  4. Intense positron source at the Munich research reactor FRM-II

    CERN Document Server

    Hugenschmidt, C; Schreckenbach, K; Strasser, B; Koegel, G; Sperr, P; Triftshaeuser, W

    2002-01-01

    The principle and the design of the in-pile positron source at the new Munich research reactor FRM-II are presented. Absorption of high-energy prompt gamma-rays from thermal neutron capture in sup 1 sup 1 sup 3 Cd generates positrons by pair production. For this purpose, a cadmium cap is placed inside the tip of the inclined beam tube SR11 in the neutron field of the reactor, where an undisturbed thermal neutron flux up to 2 x 10 sup 1 sup 4 n cm sup - sup 2 s sup - sup 1 is expected. At this position the flux ratio of thermal to fast neutrons will be better than 10 sup 4. Monte Carlo calculations showed that a mean capture rate in cadmium between 4.5 and 6.0 x 10 sup 1 sup 3 n cm sup - sup 2 s sup - sup 1 can be expected. Inside the cadmium cap a structure of platinum foils is placed for converting gamma-radiation into positron-electron pairs. The heated foils also act as positron moderators to generate monoenergetic positrons. After acceleration to 5 keV a positron beam is formed by electric lenses and guid...

  5. [Structured teaching of surgery the LMU model in Munich].

    Science.gov (United States)

    Chiapponi, C; Bruns, C J; Pilz, F; Kanz, K-G; Mutschler, W; Jauch, K-W; Siebeck, M

    2014-12-01

    The medical curriculum (MeCuM) of the Ludwig Maximilian University (LMU) in Munich is a dynamic curriculum aimed to support the learning process of all students with their different learning styles. It is based on interactive, activating teaching methods in order to increase students' interest, and on repetitive evaluation of teaching units to modify the teaching in order to meet students' needs and wishes. In this context the teaching of surgery at our faculty takes place. Besides interdisciplinary lessons where diseases are taught in cooperation with our colleagues from internal medicine, indications for surgery, complications and consequences of surgery for the patients are analysed in PBL tutorials, online cases, bedside teachings and practical teaching on the ward. Surgical skills like suturing are demonstrated in videos, practiced on models or during practical teaching on the ward and they are tested in OSCEs. During the "praktisches Jahr", the students in the last year of their medical studies are supposed to apply their practical skills besides repeating theoretical knowledge in order to pass the final examination. For this purpose they are taught in a revision course called "LMU-StaR" (revision course for the Staatsexamen). In this paper we describe in detail the teaching of surgery at our faculty.

  6. Dynamic analysis of the BMW tower in Munich

    Science.gov (United States)

    Indacochea-Beltran, Joaquin; Elgindy, Pearl; Lee, Elaine; Vignesh, Thiviya; Ansourian, Peter; Tahmasebinia, Faham; Marroquín, Fernando Alonso

    2016-08-01

    In the 1970s, world famous Austrian architect Karl Schwanzer designed an avant-garde suspended skyscraper for the new BMW headquarters. The BMW Tower was envisioned to resemble a four-cylinder motor and become a symbol for the recent flourishing success of BMW. Throughout its four decades, the BMW Tower has become the main architectural feature of modern Munich and a pride for one of the World leading car manufacturers. The structural design of the BMW Tower represented a major challenge to Germany's finest engineers because the suspended 99.5m-high structure had to whitstand not only static loading but large wind dynamic loading while having deflections within appropriate serviceability limits. Strand7 has been used to determine the stresses and deflections the structure is subjected to in order to analyse its behavior under static and dynamic loadings. Ultimately, this analysis helps to understand the nature of suspended structures in relation to the Eurocode building standards. Finally, thermal resistance has also been analysed using Strand7 to simulate a fire scenario and analyse the behaviour of the cable structure, which is the most critical building component.

  7. The Munich Compact Light Source: initial performance measures.

    Science.gov (United States)

    Eggl, Elena; Dierolf, Martin; Achterhold, Klaus; Jud, Christoph; Günther, Benedikt; Braig, Eva; Gleich, Bernhard; Pfeiffer, Franz

    2016-09-01

    While large-scale synchrotron sources provide a highly brilliant monochromatic X-ray beam, these X-ray sources are expensive in terms of installation and maintenance, and require large amounts of space due to the size of storage rings for GeV electrons. On the other hand, laboratory X-ray tube sources can easily be implemented in laboratories or hospitals with comparatively little cost, but their performance features a lower brilliance and a polychromatic spectrum creates problems with beam hardening artifacts for imaging experiments. Over the last decade, compact synchrotron sources based on inverse Compton scattering have evolved as one of the most promising types of laboratory-scale X-ray sources: they provide a performance and brilliance that lie in between those of large-scale synchrotron sources and X-ray tube sources, with significantly reduced financial and spatial requirements. These sources produce X-rays through the collision of relativistic electrons with infrared laser photons. In this study, an analysis of the performance, such as X-ray flux, source size and spectra, of the first commercially sold compact light source, the Munich Compact Light Source, is presented.

  8. Power Plant Emission Monitoring in Munich Using Differential Column Measurements

    Science.gov (United States)

    Chen, Jia; Nguyen, Hai; Toja-Silva, Francisco; Heinle, Ludwig; Hase, Frank; Butz, André

    2017-04-01

    Differential column measurements using compact Fourier transform spectrometers (EM27/SUN) have shown to be an effective method to determine the greenhouse gas emissions. Citywide measurement campaigns were carried out in Boston, Indianapolis, San Francisco, etc., focusing on city (e.g. emissions from natural gas infrastructure) and local sources. We are particularly working on validating this novel method for attributing and quantifying local emission sources. Optimal strategies are developed for measuring in different seasons with various sun elevations. We have deployed two spectrometers to monitor the CO2 and CH4 emission rates (kg s-1) of a natural gas fired combined heat-and-power plant in Munich, Germany (Heizkraftwerk Süd). We placed our spectrometers in the vicinity (differential column measurements for determining power plant emissions and explore their sensitivities to meteorological and model parameters. In addition, we present measurement strategies and experimental design criteria for different meteorological conditions and time of the year, including winter when the sun elevation is low and the column inclination becomes very important. Differential column measurements using compact spectrometers are shown to be a reliable method to monitor power plant emissions.

  9. Kak povlijajet prognoz Munich Re na vtoroi shag pensionnoi reformõ?

    Index Scriptorium Estoniae

    2003-01-01

    Maailma suurima kindlustusfirma Munich Re prognoos, et praegused kindlustajad elavad üle 90 aasta vanaks, selle mõjust meie pensionikindlustusele. Arvamust avaldavad Peeter Kreitzberg, Eret Võsa, Jaan Marks, Paavo Põld ja Olari Taal

  10. Second malignancies after Hodgkin's disease: the Munich experience.

    Science.gov (United States)

    Munker, R; Grützner, S; Hiller, E; Aydemir, U; Enne, W; Dietzfelbinger, H; Busch, M; Haas, R; Emmerich, B; Schmidt, M; Dühmke, E; Hölzel, D; Wilmanns, W

    1999-12-01

    The occurrence of second malignancies (SM) is an important late event following the treatment of Hodgkin's disease (HD). We sought to determine the incidence, the risk factors, and the prognosis of SM in our population of patients with HD. A total of 1120 patients diagnosed with HD were registered at six participating institutions in Munich (calendar period 1974-1994). The mean follow-up for the development of SM was 9.1 years. A cumulative treatment score was calculated for both radio- and chemotherapy. The relative and absolute risks of SM were established. All SM were investigated for response to treatment and outcome. We observed 85 SM [eight leukemias, 22 non-Hodgkin's lymphomas (NHL), two plasma cell neoplasias, and 53 solid tumors]. Five patients developed third malignancies. The relative risk of developing a second neoplasm was compared with that within the normal population and was 3.1-fold. The risk varied according to the category of SM. Higher relative risks (20.5 and 25.9-fold), but lower absolute risks were observed for leukemias and non-Hodgkin's lymphomas. Solid tumors had lower relative risks (1.8-fold). Splenectomy increased the risk of SM (relative risk 4.4-fold versus 2.7-fold). The risk of SM did not correlate with the initial treatment (radio- or chemotherapy) and did not decrease with prolonged follow-up. The cumulative intensity of radiotherapy, chemotherapy, or the two modalities combined correlated with the risk of SM. Since some cases occurred early after diagnosis, not all second neoplasms can be considered treatment-associated. After 15 years, an actuarial risk of 11.7% was calculated for all SM, of 1.0% for leukemias, of 3.0% for NHL, and of 7.7% for solid tumors. The prognosis of SM varied between good (thyroid cancer, melanoma: median survival 5+ years), average (breast cancer, NHL), and poor (acute myeloid leukemias, lung cancers: median survival 9 months). With the exception of NHL, second cancers often occurred in topographic

  11. Modern tandem control systems

    Science.gov (United States)

    Lutz, J. R.; Marsaudon, J. C.

    1993-04-01

    Nowadays, tandem electrostatic accelerators can benefit greatly from the growing possibilities provided by modern control facilities. Controlling an electrostatic accelerator first requires the solution of technological problems raised by the necessity of fitting inside the tank equipment which is highly stressed by the physical environment. Then, these controls can take advantage of new techniques which appear on the market. Present computer technology provides cheap powerful workstations for efficient operator interfacing, and new modular and distributed control concepts have been developed for general use in experimental physics, in data acquisition and in control systems. The general trend towards standardization is now accepted for both hardware and software and this brings benefits to the designer and the user.

  12. Scenarios for the development of electromobility in Munich; Szenarien zur Entwicklung der Elektromobilitaet in Muenchen

    Energy Technology Data Exchange (ETDEWEB)

    Brunnert, Stefan [Hochschule Weihenstephan-Triesdorf (Germany). Studiengang ' ' Management Erneuerbare Energien' '

    2011-07-01

    The change of the individual mobility on environmentally friendly and sustainable approach is not only in Germany an important concern, but also a global challenge. The main reasons for an involvement are dwindling crude oil reserves and the greenhouse effect. Due to the road traffic as one of the largest emitters of CO{sub 2} possibilities are discussed to make mobility more environmentally friendly and energy-politically sustainable. In this context, the electric car is seen as a possible component of the vision for the future of the environment and mobility. The contribution under consideration reports on the possible development of electric vehicles in Munich in 2030 based on three scenarios. The results are based on a fundamental study of the Institute fortiss GmbH (Munich, Federal Republic of Germany) and a recent study by the Research center for Energy Economics (Munich, Federal Republic of Germany) for electric vehicles.

  13. [Determination of 19 antibiotic and 2 sulfonamide metabolite residues in wild fish muscle in mariculture areas of Laizhou Bay using accelerated solvent extraction and high performance liquid chromatography-tandem mass spectrometry].

    Science.gov (United States)

    Liu, Sisi; Du, Juan; Chen, Jingwen; Zhao, Hongxia

    2014-12-01

    A sample preparation and analytical method with accelerated solvent extraction (ASE) and high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/ MS) was developed to detect 19 antibiotic (9 sulfonamides, 4 quinolones, 3 macrolides and 3 others) and 2 sulfonamide metabolite residues in fish muscle. The target compounds were extracted using ASE and purified simultaneously by a C18 resin in the extraction cell. The extracts were evaporated to dryness, and redissolved with the initial mobile phase for HPLC-MS/MS analysis after freezing centrifugation (10,000 r/min, -4 °C) to remove the fat and other matrix compounds further. The separation of the analytes was carried out on an Xterra MS C18 column with methanol-acetonitrile (1:1, v/v) as mobile phase A and 0. 1% formic acid (containing 0. 1% ammonium formate) as mobile phase B. The spiked recoveries of the method were 55. 2%-113. 3%, with the relative standard deviations of 0. 1% - 17. 6% (n = 6). The limits of detection ranged from 0. 003 to 0. 6 ng/g. The method was applied to two fish (Synechogobius hasta and Liza haematocheilus) collected in mariculture areas of Laizhou Bay and six antibiotics were detected, in which the mass concentrations of norfloxacin were highest with mean values of 67. 01 and 27. 58 ng/g, respectively. The method is simple, rapid, highly sensitive, and useful in the study on exposure levels and environmental behavior of the antibiotics.

  14. A Universal Model of Giftedness--An Adaptation of the Munich Model

    Science.gov (United States)

    Jessurun, J. H.; Shearer, C. B.; Weggeman, M. C. D. P.

    2016-01-01

    The Munich Model of Giftedness (MMG) by Heller and his colleagues, developed for the identification of gifted children, is adapted and expanded, with the aim of making it more universally usable as a model for the pathway from talents to performance. On the side of the talent-factors, the concept of multiple intelligences is introduced, and the…

  15. The Munich MIDY Pig Biobank – A unique resource for studying organ crosstalk in diabetes

    Directory of Open Access Journals (Sweden)

    Andreas Blutke

    2017-08-01

    Conclusions: The broad spectrum of well-defined biosamples in the Munich MIDY Pig Biobank that will be available to the scientific community provides a unique resource for systematic studies of organ crosstalk in diabetes in a multi-organ, multi-omics dimension.

  16. A Universal Model of Giftedness--An Adaptation of the Munich Model

    Science.gov (United States)

    Jessurun, J. H.; Shearer, C. B.; Weggeman, M. C. D. P.

    2016-01-01

    The Munich Model of Giftedness (MMG) by Heller and his colleagues, developed for the identification of gifted children, is adapted and expanded, with the aim of making it more universally usable as a model for the pathway from talents to performance. On the side of the talent-factors, the concept of multiple intelligences is introduced, and the…

  17. Gold for Munich's new skyscraper; Gold fuer Muenchens neuen Skyscraper

    Energy Technology Data Exchange (ETDEWEB)

    Meinig, Melanie

    2011-07-01

    At the beginning of December 2010 the project 'The m.pire' planned by Helmut Jahn received the DGNB certification in gold and thus the highest award for sustainability within the range of real estate of the German Sustainable Building Council DGNB (Stuttgart, Federal Republic of Germany). The fifth-piece building ensemble sets a clear accent regarding to urban development in the North of Munich (Federal Republic of Germany).

  18. Meaningful, entertaining, popular and ‘Bavarian’: art into design in nineteenth century Munich

    Directory of Open Access Journals (Sweden)

    Stefan Muthesius

    2014-12-01

    Full Text Available Among European regional stereotypes few come across as strongly and consistently as ‘Bavaria’. Its strength is derived from the ways in which it appears to be firmly and comprehensively grounded in its land and its people. This article traces the way in which some of the stereotype’s associated forms and images, principally those related to the domestic environment, were first conceived during the nineteenth century. The principal claim is that it was the nineteenth century artists, architects and designers in the Kunststadt Munich, who, helped by the critics, arrived at very specific valorisations of their designs, which could then be applied in an essentialist way to all artefacts of the region, old or new. The article divides the Munich design activities into two phases. During the 1850s designers aimed for a poetic and ‘volkstümlich / popular’ kind of decoration of common objects, including scenes from Bavarian ‘folk’ poetry. In the second phase, during the 1870s and 1880s, interest turned more directly to the domestic environment of Alpine houses, valorising a plain wooden character. Clearly, an absolute belief in in a primeval and unchanging ‘Bavaria’ cannot be entertained any more. But neither should one classify it all as modern kitsch. The latter attitude must be the reason why the subject has hardly been touched on in the copious art histories of Munich so far.

  19. [Evaluating language acquisition using the Early Language Milestone (ELM) and Munich developmental scales].

    Science.gov (United States)

    Páez-Pineda, Oscar D; Valencia-Valencia, Doris; Ortiz Calderón, Martha Vanessa

    2014-01-01

    Evaluating language development by comparing the Munich Development method to the Early Language Milestone scale for identifying both diagnostic tests' agreement and enriching neurodevelopmental consultation. The clinical histories of a cohort of 129 children were evaluated, as prematurity is a risk factor for deviation in children's language development. The children had less than 40 weeks gestational age and 0 to 12 months corrected age. They were given both tests between 2008 and 2011. The results from both scales were compared regarding receptive and expressive language and visual response (Early Language Milestone scale) and evaluation of verbal response, vocal play, understanding and expression (Munich scale). Student's T-test was used for comparing means for paired samples. Results: A statistically significant correlation (p<0.05) was found between both tests and between them and corrected age. It was seen that the higher the corrected age, the greater correlation there was between tests. The Early Language Milestone and Munich Development scales, regarding their components dealing with language, both represent useful tools for following-up premature children's language development.

  20. Tissue expression of TRPC3 and TRPC6 in hypertensive Munich Wistar Frömter rats showing proteinuria

    DEFF Research Database (Denmark)

    Liu, Ying; Thilo, Florian; Kreutz, Reinhold

    2010-01-01

    We investigated whether alterations of transient receptor potential canonical (TRPC) channel expression may be observed in tissues from Munich Wistar Frömter (MWF) rats showing proteinuria compared to control Wistar rats.......We investigated whether alterations of transient receptor potential canonical (TRPC) channel expression may be observed in tissues from Munich Wistar Frömter (MWF) rats showing proteinuria compared to control Wistar rats....

  1. Fault analysis as part of urban geothermal exploration in the German Molasse Basin around Munich

    Science.gov (United States)

    Ziesch, Jennifer; Tanner, David C.; Hanstein, Sabine; Buness, Hermann; Krawczyk, Charlotte M.; Thomas, Rüdiger

    2017-04-01

    Faults play an essential role in geothermal exploration. The prediction of potential fluid pathways in urban Munich has been started with the interpretation of a 3-D seismic survey (170 km2) that was acquired during the winter of 2015/2016 in Munich (Germany) within the Bavarian Molasse Basin. As a part of the research project GeoParaMoL*, we focus on the structural interpretation and retro-deformation analysis to detect sub-seismic structures within the reservoir and overburden. We explore the hydrothermal Malm carbonate reservoir (at a depth of 3 km) as a source of deep geothermal energy and the overburden of Tertiary Molasse sediments. The stratigraphic horizons, Top Aquitan, Top Chatt, Top Bausteinschichten, Top Lithothamnien limestone (Top Eocene), Top and Base Malm (Upper Jurassic), together with the detailed interpretation of the faults in the study area are used to construct a 3-D geological model. The study area is characterised by synthetic normal faults that strike parallel to the alpine front. Most major faults were active from Upper Jurassic up to the Miocene. The Munich Fault, which belongs to the Markt-Schwabener Lineament, has a maximum vertical offset of 350 metres in the central part, and contrary to previous interpretation based on 2-D seismic, this fault dies out in the eastern part of the area. The south-eastern part of the study area is dominated by a very complex fault system. Three faults that were previously detected in a smaller 3-D seismic survey at Unterhaching, to the south of the study area, with strike directions of 25°, 45° and 70° (Lüschen et al. 2014), were followed in to the new 3-D seismic survey interpretation. Particularly noticeable are relay ramps and horst/graben structures. The fault with a strike of 25° ends in three big sinkholes with a maximum vertical offset of 60 metres. We interpret this special structure as fault tip horsetail-structure, which caused a large amount of sub-seismic deformation. Consequently, this

  2. Argonne Tandem Linac Accelerator System (ATLAS)

    Data.gov (United States)

    Federal Laboratory Consortium — ATLAS is a national user facility at Argonne National Laboratory in Argonne, Illinois. The ATLAS facility is a leading facility for nuclear structure research in the...

  3. GIC4117串列加速器外束 PIXE/PIGE 分析系统%External Beam PIXE/PIGE Analysis Facility on GIC4117 Tandem Accelerator

    Institute of Scientific and Technical Information of China (English)

    王广甫; 李旭芳; 初钧晗; 于令达; 安坤; 吴冰冰

    2014-01-01

    本文介绍在北京师范大学GIC4117串列加速器上建立的外束PIXE/PIGE分析系统,和基于此系统的薄样品外束PIXE/PIGE定量分析方法。给出了2010年Teflon滤膜采集的361个气溶胶样品外束PIXE分析得到的各元素平均探测限和最低探测限,并同真空 PIXE分析探测限进行了比较。利用标准样品给出了激发曲线不同坪区薄样品外束PIGE分析F和Na的探测限,通过测定19 F(p ,p′γ)19 F激发的197 keV γ射线得到的F的探测限可达73.9 ng · cm -2,Na的探测限可达198.9 ng · cm-2。%At the GIC4117 1.7 MV tandem accelerator of Beijing Normal University ,an external beam PIXE/PIGE analysis facility was established ,and the analysis method of thin samples was developed on the facility .The average and the lowest limits of detec-tion (LOD) of multielement for the external beam PIXE analysis of 361 PM2.5 samples collected on Teflon membrane filters in 2010 were given ,and compared with those of vacuum PIXE analysis .The results of external beam PIGE analysis of standard samples show that the LOD can be as low as 73.9 ng · cm -2 and 198.9 ng · cm -2 for F (using 197 keV γ-ray from 19 F(p ,p′γ) 19 F reaction) and Na ,respectively .

  4. [Inception of institutionalization of clinical neurology in Munich (1913-1933): with particular focus on Eugen von Malaisé].

    Science.gov (United States)

    Voss, H

    2015-02-01

    At the University of Munich the teaching and treatment of neurological diseases had been covered by internists since the last quarter of the nineteenth century. Under the direction of Bumke the psychiatric clinic also laid claim to the representation of neurology starting in 1924. However, the military departments for nerve- and brain-injured soldiers, which were founded during WWI, developed into non-academic neurological treatment centres in Munich with donations from the German-American philanthropist Heckscher and the initiative of war invalids organisations. In 1925 the Heckscher Nerven-Heil- und Forschungsanstalt was established as the first neurological hospital in Munich. The main characters involved in this development were the neurologist Eugen von Malaisé and the psychiatrist Max Isserlin. With the early death of von Malaisé in 1923 neurology in Munich lost an important advocate of its institutional independence. The dismissal, prosecution and expulsion of the Jewish chief physician Isserlin was the second heavy blow to the efforts towards autonomy of neurology in Munich.

  5. The Munich High Ability Test Battery (MHBT: A multidimensional, multimethod approach

    Directory of Open Access Journals (Sweden)

    CHRISTOPH PERLETH

    2008-06-01

    Full Text Available After a brief introduction the theoretical basis of the Munich High Ability Test-Battery (MHBT will be outlined in the first part of the article. The MHBT has been developed in the framework of the Munich longitudinal study of giftedness and talent. The MHBT includes not only cognitive predictors measuring several dimensions and types of giftedness concerning intellectual, creative or social abilities etc., but also giftedness-relevant non-cognitive personality and social moderators measuring interests, motivations, learning emotions, self-concepts or family and school climate, educational style, quality of instruction, etc. The MHBT-instruments (different scales and dimensions are described in greater detail.In the second part of the article, after dealing with the objectivity, the reliability, and the validity of the MHBT, the authors discuss the standardization procedure including the development of grade-based T-norms respectively as well as several talent-profiles, e.g. of gifted achievers vs. underachievers, intellectual, creative, social talents or linguistic, math, science talent profiles etc. Finally, examples of talent search for gifted programs and case studies on the basis of MHBT should illustrate multidimensional identification procedures.The MHBT fulfills the most relevant assessment tasks belonging to the gifted educational and counseling practice. The usefulness of the MHBT in the framework of giftedness research as well as of gifted program evaluation studies has also been proven in the last decade. Hence the MHBT offers many opportunities to assessing giftedness and talent.

  6. Cubierta para naves de grandes dimensiones en hormigón, Munich (Alemania Federal

    Directory of Open Access Journals (Sweden)

    Bomhard, H.

    1972-05-01

    Full Text Available This article describes the study, design and building of wide span concrete halls which, at present, are greatly influenced by the advances made in pre-stressed concrete, préfabrication and the development of modern building methods, as well as the new techniques in building with light concrete. The influence which gave origin to these halls is also described. Chosen as an example is the hall, with a span of 150 metres and a maximum hight of 27.30 metres, for the Munich goods station, showing the importance of this type of construction.El artículo describe el estudio, proyecto y construcción de naves de gran luz en hormigón que, en el momento actual, están decisivamente influenciadas por los adelantos en hormigón pretensado, en prefabricación y por el desarrollo de los modernos métodos de construcción, así como por las nuevas técnicas de la construcción en hormigones ligeros. Se detalla igualmente la influencia que originan estas naves de grandes dimensiones. Se toma como ejemplo la nave, de 150 m de luz y 27,30 m de altura máxima, para la estación de mercancías de Munich, haciendo patente su gran importancia en este tipo de construcciones.

  7. Low emission zone Munich. First results; Umweltzone Muenchen. Eine erste Bilanz

    Energy Technology Data Exchange (ETDEWEB)

    Cyrys, Josef [Helmholtz Zentrum Muenchen - Deutsches Forschungszentrum fuer Gesundheit und Umwelt, Inst. fuer Epidemiologie, Neuherberg (Germany); Wissenschaftszentrum Umwelt (WZU) der Univ. Augsburg (Germany); Peters, Annette [Helmholtz Zentrum Muenchen - Deutsches Forschungszentrum fuer Gesundheit und Umwelt, Inst. fuer Epidemiologie, Neuherberg (Germany); Wichmann, H. Erich [Helmholtz Zentrum Muenchen - Deutsches Forschungszentrum fuer Gesundheit und Umwelt, Inst. fuer Epidemiologie, Neuherberg (Germany); Inst. fuer Medizinische Informationsverarbeitung, Biometrie und Epidemiologie der Ludwig-Maximilians-Univ. Muenchen, Lehrstuhl fuer Epidemiologie, Neuherberg (Germany)

    2009-07-01

    In order to reduce the PM{sub 10} concentrations in the ambient air in Munich, Germany two measures have been introduced in 2008. In February 2008 the law forbidding transit of vehicles heavier than 3.5 tons through the city area took effect. Additionally, a low emission zone was established in the inner city of Munich in October 2008. In our analysis we study the impact of those measures on the ambient PM{sub 10} concentrations by comparing two 4 months periods, the first one before the measures became operative and the second one after it. By means of a reference station located in a background area we adjusted our analysis on the influence of the meteorological conditions. A reduction of the relative PM{sub 10} burden was observed and the magnitude of the decrease was in line with the results calculated by modelling. The decrease was small and especially pronounced at traffic sites. Due to the kind of measures it is obvious that the reduced fraction of PM{sub 10} was mostly generated by traffic (and especially diesel engines), which is known to be especially relevant for human health. (orig.)

  8. OECD Global Science Forum's Astronomy Workshop to take place in Munich

    Science.gov (United States)

    2003-11-01

    On December 1 to 3, the city of Munich (Bavaria, Germany) will be the venue for a "Workshop on Large Scale Programmes and Projects in Astronomy and Astrophysics" organised by the Organisation for Economic Co-operation and Development (OECD) Global Science Forum in co-operation with the European Southern Observatory (ESO). The Workshop will be chaired by Ian Corbett (ESO). The Global Science Forum brings together science policy officials from the OECD countries. The delegates, who meet twice a year, look at a range of generic issues in science funding and seek to identify and maximise opportunities for international co-operation in basic scientific research. This Workshop was proposed by Germany and agreed by the delegates to the Global Science Forum in June. Government officials and scientists will be able to review in detail the information and the observational and technological advances needed for major progress in the field during the next 15- 20 years. The research subjects reviewed will cover the full range from planets, solar systems, life in the Universe, stars, galaxies, extreme objects to cosmology. Related technological challenges, virtual observatories and other data handling issues will also be considered. The primary objective is to specify the policy issues relating to priority-setting, planning, funding and, above all, international co-ordination and co-operation. The Workshop will focus on issues relevant to the process through which astronomy advances, and will highlight means to enhance that process in light of longer-term scientific and political trends. There will probably be a follow-up meeting early in 2004, from which a policy level report will be prepared for consideration by the Global Science Forum and so transmitted to governments. Eighteen delegations, from non-OECD as well as OECD countries, will attend, each consisting of senior programme managers from the national ministry, funding agency or research council, and one or more senior

  9. Leadership and cooperation at the general medicine department of LMU Munich: Good grades despite difficult conditions.

    Science.gov (United States)

    Schelling, Jörg; Braun, Susanne

    2011-01-01

    The relevance of general medicine at German universities will increase over the next few years. Consequently, the discussion of teaching content and even more the improvement of the structures within the still small and dependent departments of general medicine are of major importance. The example of our department at LMU Munich shows which challenges for leadership and cooperation result from lack of financial and personnel structure. The project "cooperation culture" that the department has conducted in collaboration with the LMU Center for Leadership and People Management is presented as a means to promote leadership and cooperation. This project can serve as an inspiration for the coordinators of smaller departments of general medicine at other German universities that are also striving to improve their structure and their position within the university.

  10. Development of the one dimensional Fog Model PAFOG for operational Use at Munich Airport

    Science.gov (United States)

    Thoma, C.; Schneider, W.; Rohn, M.; Röhner, P.; Beckmann, B.-R.; Masbou, M.; Bott, A.

    2010-07-01

    Reduced visibility due to heavy fog is a hazard for land, sea, and air traffic. Especially for air transportation systems, reduced visibility leads to significant cost increments. Therefore, it is of particular importance to predict poor visibility fog events at airports accurately. In iPort-VIS, part of an aviation research program funded by the German Ministry for economy and technology, a site specific fog forecast system for Munich airport will be developed in cooperation between DWD, the German Aviation Control (DFS) and University of Bonn. The principal component of this forecast system is the one dimensional fog forecast model PAFOG (PArameterised FOG) that will be upgraded to operational use. The model consists of a parameterised microphysics scheme. The particle size distribution of cloud droplets is taken into account by a lognormal distribution and the visibility is calculated dependent on liquid water content and droplet concentration based on the Koschmieder formula. The turbulence in the atmospheric boundary layer is treated by the Mellor and Yamada closure scheme of order 2.5 in which a prognostic equation for the Turbulent Kinetic Energy (TKE) is solved. Radiative transports are considered by a Delta-Two-Stream Method with 18 spectral bands. Due to the fact that fog is a small scale complex phenomenon with high spatial and temporal variability, detailed knowledge of the atmospheric boundary layer structure is fundamental to get a realistic fog forecast. A time nudging scheme has been developed for integrating local observations (vertical profiles of temperature and specific humidity) periodically during the forecast. The system has been tested in several case studies with data from Lindenberg observatory and will be adapted to Munich airport with a new measurement system that will be installed by DWD. A second version of the nudging scheme, driven by the forecast of the high-resolution COSMO-DE model by DWD, is currently under development.

  11. Effects of extreme spring temperatures on phenology: a case study from Munich and Ingolstadt

    Science.gov (United States)

    Jochner, Susanne; Menzel, Annette

    2010-05-01

    Extreme events - e.g. warm spells or heavy precipitation events - are likely to increase in the future both in frequency and intensity. Therefore, research on extreme events gains new importance; also in terms of plant development which is mostly triggered by temperatures. An arising question is how plants respond to an extreme warm spell when following an extreme cold winter season. This situation could be studied in spring 2009 in the greater area of Munich and Ingolstadt by phenological observations of flowering and leaf unfolding of birch (Betula pendula L.) and flowering of horse chestnut (Aesculus hippocastanum L.). The long chilling period of winter 2008 and spring 2009 was followed by an immediate strong forcing of flowering and leaf unfolding, especially for birch. This extreme weather situation diminished the difference between urban and rural dates of onset. Another important fact that could be observed in the proceeding period of December 2008 to April 2009 was the reduced temperature difference among urban and rural sites (urban heat island effect). Long-term observations (1951-2008) of the phenological network of the German Meteorological Service (DWD) were used to identify years with reduced urban-rural differences between onset times in the greater area of Munich in the past. Statistical analyses were conducted in order to answer the question whether the sequence of extreme warm and cold events leads to a decreased difference in phenological onset times or if this behaviour can be attributed to extreme warm springs themselves or to the decreased urban heat island effect which is mostly affected by general atmospheric circulation patterns.

  12. Field Test: Results of Tandem Walk Performance Following Long-Duration Spaceflight

    Science.gov (United States)

    Rosenberg, M. J. F.; Reschke, M. F.; Cerisano, J. M.; Kofman, I. S.; Fisher, E. A.; Gadd, N. E.; May-Phillips, T. R.; Lee, S. M. C.; Laurie, S. S.; Stenger, M. B.; Bloomberg, J. J.; Mulavara, A.; Kozlovskaya, I.; Tomilovskaya, E.

    2016-01-01

    BACKGROUND: Coordinated locomotion has proven to be challenging for many astronauts following long duration spaceflight. As NASA's vision for spaceflight points toward interplanetary travel, we must prepare for unassisted landings, where crewmembers may need to perform mission critical tasks within minutes of landing. Thus, it is vital to develop a knowledge base from which operational guidelines can be written that define when astronauts can be expected to safely perform certain tasks. Data obtained during the Field Test experiment (FT) will add important insight to this knowledge base. Specifically, we aim to develop a recovery timeline of functional sensorimotor performance during the first 24 hours and several days after landing. METHODS: FT is an ongoing study of 30 long-duration ISS crewmembers. Thus far, 9 have completed the full FT (5 U.S. Orbital Segment [USOS] astronauts and 4 Russian cosmonauts) and 4 more consented and launching within the next year. This is in addition to the eighteen crewmembers that participated in the pilot FT (11 USOS and 7 Russian crewmembers). The FT is conducted three times preflight and three times during the first 24 hours after landing. All crewmembers were tested in Kazakhstan in either the medical tent at the Soyuz landing site (one hour post-landing), or at the airport (four hours post-landing). The USOS crewmembers were also tested at the refueling stop (12 hours post-landing) and at the NASA Johnson Space Center (24 hours post-landing) and a final session 7 days post-landing. Crewmembers are instrumented with 9 inertial measurement unit sensors that measure acceleration and angular displacement (APDM's Emerald Sensors) and foot pressure-sensing insoles that measure force, acceleration, and center of pressure (Moticon GmbH, Munich, Germany) along with heart rate and blood pressure recording instrumentation. The FT consists of 12 tasks, but here we will focus on the most challenging task, the Tandem Walk, which was also

  13. Test of the Tandem transmission at low terminal voltages

    Energy Technology Data Exchange (ETDEWEB)

    Rehm, K.E.; Blumenthal, D.; Gehring, J. [and others

    1995-08-01

    For a planned experiment with {sup 18}F beams at energies below 1 MeV/u the transmission of the Tandem-Linac system was investigated. The energies required in the experiment are typically around 600 keV/u, which for the most abundant charge states for F(4{sup +}) corresponds to terminal voltages between 2-3 MV. We studied the transmission from the source to the tandem accelerator and to the spectrograph in area II with {sup 18}O and {sup 19}F beams using two different approaches. In the first method only the tandem accelerator was used producing a 14-MeV DC {sup 18}O beam. In the second method a pulsed beam was accelerated to 33 MeV with the tandem accelerator followed by deceleration to 14 MeV with the first 9 resonators of ATLAS. The total transmission from ion source to target was in both cases about 10%. Because of the smaller complexity we used the first method for the {sup 18}F experiment. In future runs we are planning to use the electrostatic lens in the terminal of the tandem to improve the overall transmission.

  14. Tandem mobile robot system

    Energy Technology Data Exchange (ETDEWEB)

    Buttz, James H. (Albuquerque, NM); Shirey, David L. (Albuquerque, NM); Hayward, David R. (Albuquerque, NM)

    2003-01-01

    A robotic vehicle system for terrain navigation mobility provides a way to climb stairs, cross crevices, and navigate across difficult terrain by coupling two or more mobile robots with a coupling device and controlling the robots cooperatively in tandem.

  15. Development of a Compton Camera for Online Range Monitoring of Laser-Accelerated Proton Beams via Prompt-Gamma Detection

    NARCIS (Netherlands)

    Thirolf, P.G.; Lang, C.; Aldawood, S.; Van der Kolff, H.G.; Maier, L.; Schaart, D.R.; Parodi, K.

    2014-01-01

    Presently large efforts are conducted in Munich towards the development of proton beams for bio-medical applications, generated via the technique of particle acceleration from high-power, short-pulse lasers. While so far mostly offline diagnostics tools are used in this context, we aim at developing

  16. Bucharest heavy ion accelerator facility

    Energy Technology Data Exchange (ETDEWEB)

    Ceausescu, V.; Dobrescu, S.; Duma, M.; Indreas, G.; Ivascu, M.; Papureanu, S.; Pascovici, G.; Semenescu, G.

    1986-02-15

    The heavy ion accelerator facility of the Heavy Ion Physics Department at the Institute of Physics and Nuclear Engineering in Bucharest is described. The Tandem accelerator development and the operation of the first stage of the heavy ion postaccelerating system are discussed. Details are given concerning the resonance cavities, the pulsing system matching the dc beam to the RF cavities and the computer control system.

  17. [Anatomical Vitamin C-Research during National Socialism and the Post-war Period: Max Clara's Human Experiments at the Munich Anatomical Institute].

    Science.gov (United States)

    Schûtz, Mathias; Schochow, Maximilian; Waschke, Jens; Marckmann, Georg; Steger, Florian

    2014-01-01

    In autumn of 1942, Max Clara (1899-1966) became chairman of the anatomical institute Munich. There, he intensified his research concerning the proof of vitamin C with the bodies of executed prisoners which were delivered by the Munich-Stadelheim prison. This research on human organs was pursued by applying ascorbic acid (Cebion) to prisoners before their execution. The paper investigates this intensified and radicalized anatomical research through human experiments, which Max Clara conducted in Munich and published from Istanbul during the postwar years, as well as its scientific references from the Nazi period.

  18. Volcanic ash from Iceland over Munich: mass concentration retrieved from ground-based remote sensing measurements

    Science.gov (United States)

    Gasteiger, J.; Gro{ß}, S.; Freudenthaler, V.; Wiegner, M.

    2011-03-01

    Volcanic ash plumes, emitted by the Eyjafjallajökull volcano (Iceland) in spring 2010, were observed by the lidar systems MULIS and POLIS in Maisach (near Munich, Germany), and by a CIMEL Sun photometer and a JenOptik ceilometer in Munich. We retrieve mass concentrations of volcanic ash from the lidar measurements; spectral optical properties, i.e.~extinction coefficients, backscatter coefficients, and linear depolarization ratios, are used as input for an inversion. The inversion algorithm searches for model aerosol ensembles with optical properties that agree with the measured values within their uncertainty ranges. The non-sphericity of ash particles is considered by assuming spheroids. Optical particle properties are calculated using the T-matrix method supplemented by the geometric optics approach. The lidar inversion is applied to observations of the pure volcanic ash plume in the morning of 17 April 2010. We find 1.45 g m-2 for the ratio between the mass concentration and the extinction coefficient at λ = 532 nm, assuming an ash density of 2.6 g cm-3. The uncertainty range for this ratio is from 0.87 g m-2 to 2.32 g m-2. At the peak of the ash concentration over Maisach the extinction coefficient at λ = 532 nm was 0.75 km-1 (1-h-average), which corresponds to a maximum mass concentration of 1.1 mg m-3 (0.65 to 1.8 mg m-3). Model calculations show that particle backscatter at our lidar wavelengths (λ ≤ 1064 nm), and thus the lidar retrieval, is hardly sensitive to large particles (r ≳ 3 μm); large particles, however, may contain significant amounts of mass. Therefore, as an independent cross check of the lidar retrieval and to investigate the presence of large particles in more detail, we model ratios of sky radiances in the aureole of the Sun and compare them to measurements of the CIMEL. These ratios are sensitive to particles up to r ≈ 10 μm. This approach confirms the mass concentrations from the lidar retrieval. We conclude that synergistic

  19. Total Column Greenhouse Gas Monitoring in Central Munich: Automation and Measurements

    Science.gov (United States)

    Chen, Jia; Heinle, Ludwig; Paetzold, Johannes C.; Le, Long

    2016-04-01

    It is challenging to use in-situ surface measurements of CO2 and CH4 to derive emission fluxes in urban regions. Surface concentrations typically have high variance due to the influence of nearby sources, and they are strongly modulated by mesoscale transport phenomena that are difficult to simulate in atmospheric models. The integrated amount of a tracer through the whole atmosphere is a direct measure of the mass loading of the atmosphere given by emissions. Column measurements are insensitive to vertical redistribution of tracer mass, e.g. due to growth of the planetary boundary layer, and are also less influenced by nearby point sources, whose emissions are concentrated in a thin layer near the surface. Column observations are more compatible with the scale of atmospheric models and hence provide stronger constraints for inverse modeling. In Munich we are aiming at establishing a regional sensor network with differential column measurements, i.e. total column measurements of CO2 and CH4 inside and outside of the city. The inner-city station is equipped with a compact solar-tracking Fourier transform spectrometer (Bruker EM27/SUN) in the campus of Technische Universität München, and our measurements started in Aug. 2015. The measurements over seasons will be shown, as well as preliminary emission studies using these observations. To deploy the compact spectrometers for stationary monitoring of the urban emissions, an automatic protection and control system is mandatory and a challenging task. It will allow solar measurements whenever the sun is out and reliable protection of the instrument when it starts to rain. We have developed a simplified and highly reliable concept for the enclosure, aiming for a fully automated data collection station without the need of local human interactions. Furthermore, we are validating and combining the OCO-2 satellite-based measurements with our ground-based measurements. For this purpose, we have developed a software tool that

  20. Generation of a high-brightness pulsed positron beam for the Munich scanning positron microscope

    Energy Technology Data Exchange (ETDEWEB)

    Piochacz, Christian

    2009-11-20

    Within the present work the prerequisites for the operation of the Munich scanning positron microscope (SPM) at the high intense neutron induced positron source Munich (NEPOMUC) were established. This was accomplished in two steps: Firstly, a re-moderation device was installed at the positron beam facility NEPOMUC, which enhances the brightness of the positron beam for all connected experiments. The second step was the design, set up and initial operation of the SPM interface for the high efficient conversion of the continuous beam into a bunched beam. The in-pile positron source NEPOMUC creates a positron beam with a diameter of typically 7 mm, a kinetic energy of 1 keV and an energy spread of 50 eV. The NEPOMUC re-moderator generates from this beam a low energy positron beam (20 - 200 eV) with a diameter of less than 2 mm and an energy spread well below 2.5 eV. This was achieved with an excellent total efficiency of 6.55{+-}0.25 %. The re-moderator was not only the rst step to implement the SPM at NEPOMUc, it enables also the operation of the pulsed low energy positron beam system (PLEPS). Within the present work, at this spectrometer rst positron lifetime measurements were performed, which revealed the defect types of an ion irradiated uranium molybdenum alloy. Moreover, the instruments which were already connected to the positron beam facility bene ts considerably of the high brightness enhancement. In the new SPM interface an additional re-moderation stage enhances the brightness of the beam even more and will enable positron lifetime measurements at the SPM with a lateral resolution below 1 {mu}m. The efficiency of the re-moderation process in this second stage was 24.5{+-}4.5 %. In order to convert high efficiently the continuous positron beam into a pulsed beam with a repetition rate of 50 MHz and a pulse duration of less than 50 ps, a sub-harmonic pre-bucher was combined with two sine wave bunchers. Furthermore, the additional re-moderation stage of the

  1. Munich installs provider-neutral building management and control system; Landeshauptstadt Muenchen realisiert firmenneutrale Gebaeudeleittechnik

    Energy Technology Data Exchange (ETDEWEB)

    Schmid, W.

    1998-10-01

    Since April 1995, a pilot project is running in Munich for comprehensive energy management of all 1600 city-owned buildings. There will be a central facility management system which communicates with automation nodes in the individual buildings via the urban telephone network (ISDN-HICOM) or the Telekom ISDN network. In order to be independent of suppliers, an open system (FND) was chosen. Connection of about 600 buildings is envisaged as a medium-term goal. 150 buildings were connected in early 1998. [Deutsch] Seit April 1995 laeuft in Muenchen ein Pilotprojekt zum Aufbau eines umfassenden Energiemanagements fuer die rund 1600 staedtischen Gebaeude der bayerischen Metropole. Basis dieser Entwicklung ist ein uebergeordnetes Gebaeudeleitsystem, das aeber das staedtische Telefonnetz (ISDN-HICOM) bzw. das ISDN-Netz der Telekom mit den sogenannten Gebaeude-Automations-Knoten (GA-Knoten) in den jeweiligen Liegenschaften kommuniziert. Aus Gruenden der Firmenneutralitaet waehlten die Muenchner ein offenes System auf der Basis des firmenneutralen Datenuebertragungssystems (FND). Mittelfristiges Ziel ist die Aufschaltung von rund 600 Liegenschaften, wobei Anfang 1998 bereits 150 Gebaeude fixiert waren. (orig.)

  2. [Segregation of pigment cell anomalies in Munich miniature swine (MMS) Troll crossed with German Landrace].

    Science.gov (United States)

    Müller, S; Wanke, R; Distl, O

    1995-10-01

    In order to study the inheritance of melanocytic lesions in the Munich Miniature Swine (MMS) Troll, we established the F1-, F2- and R1-generations, starting with one melanoma-bearing MMS-Troll boar and four German Landrace sows as founder animals. A total of 168 animals were born, 24 in the F1-, 111 in the F2-, 19 in the B1DL-, and 14 in the B1Troll-generation. Benign lesions with lentigoid melanocytic hyperplasia or nests of hyperplastic melanocytes like in human junctional nevus were seen in 10 (41.7%) F1-, 17 (15.3%) F2-, 2 (10.5%) B1DL-, and 6 B1Troll-animals. Malignant melanomas occurred only in the F2-(4 animals; 3.6%) and in the B1Troll-(1 animal; 7.1%) generation. The observed segreation suggests different modes of inheritance for nevi and melanomas. The segregation of nevi can be explained by a major gene model with additional modification by a polygenic component. For melanoma, a major gene model does not fit the data sufficiently. Therefore, a two-or-three-locus model with doubled or tripled recessive affected animals has to be supposed for the inheritance of melanoma. Influence of SLA-haplotypes could not be observed.

  3. “Inspired by real events”—Media (and Memory in Steven Spielberg’s MUNICH (2005

    Directory of Open Access Journals (Sweden)

    Thomas Nachreiner

    2016-02-01

    Full Text Available Steven Spielberg’s 2005 film Munich tells the story of an Israeli counter-terrorist team in the aftermath of the hijacking and massacre at the Olympic Games in 1972. The film spawned broad discussion about its historical accuracy and its political standpoint. While criticism primarily focused on the historiographical representation of the actions depicted, this paper analyzes in two steps the genuinely filmic mode of historical representation ofMunich. First, the analysis discusses the interplay of two conflicting narrative strategies that negotiate the character development with the political struggle. And second, analysis focuses on the two formal devices at the core of the narrative conflict: The reflexive framing of television in the depiction of the Munich massacre as a traumatic media event and the excessive transformation of its memory in a series of flashbacks. Such elaboration of the narrative and formal strategies reveals the implicit historiographical structures of the film and suggests that the notion of ‘cultural trauma’ serves as the preferential—but problematic—template in telling the history of terrorism and violence.

  4. Cubierta del Estadio Olímpico. en Munich - Alemania Federal

    Directory of Open Access Journals (Sweden)

    Editorial, Equipo

    1973-03-01

    Full Text Available The roof of the Olympic Stadium in Munich is like a gigantic tent on a network of cables, hung from masts, covering an area of 74,800 m2. Three stages were followed for building it: 1. Building and erecting the steel masts, and anchoring components. 2. Making and erecting the cable mesh. 3. Placing and welding the acrylic glass roof. The perfect planning of the work should be stressed, as all the cables were supplied on site with their final measurements, marked for easy assembly. The masts are steel tubes, pointed like cones at the end. They are made up of 37 mm thick sheets in the fust and 40 mm in the cones. The diameters reach 2.8 m and the lengths range between 41.1 m and 80 m. These masts rest on neoprene supports, fitted in ball bearings. The metal net is made up of square mesh, measuring 75 cm each side, and is placed in a 457 m long marginal cable. The acrylic roof is 4 mm thick. Sheets were thermally welded to obtain 300x300 m components, which were joined resiliently.La cubierta del Estadio Olímpico de Munich se asemeja a una gigantesca tienda de campaña sobre red de cables, suspendida de mástiles, que cubre una superficie de 74.800 m2. Para su construcción se siguieron tres etapas: 1.* Construcción y colocación de los mástiles de acero, y elementos de anclaje. 2.* Fabricación y colocación de las mallas de cables. 3.* Colocación y soldadura de la cubierta de vidrio acrílico. Es de destacar la perfecta planificación de la obra, ya que todos los cables fueron suministrados en obra con sus medidas definitivas y marcados para facilitar su colocación. Los mástiles son tubos de acero apuntados en conos en sus extremos. Están formados por chapas de 37 mm de espesor en el fuste y de 40 mm en los conos. Los diámetros llegan a 2,8 m y las longitudes oscilan entre los 41,1 m y los 80 m. Estos mástiles se apoyan sobre soportes de neopreno colocados en cojinetes de bolas. La red metálica está constituida por mallas cuadradas de

  5. Unifying physics of accelerators, lasers and plasma

    CERN Document Server

    Seryi, Andrei

    2015-01-01

    Unifying Physics of Accelerators, Lasers and Plasma introduces the physics of accelerators, lasers and plasma in tandem with the industrial methodology of inventiveness, a technique that teaches that similar problems and solutions appear again and again in seemingly dissimilar disciplines. This unique approach builds bridges and enhances connections between the three aforementioned areas of physics that are essential for developing the next generation of accelerators.

  6. Munich Oktoberfest experience: remarkable impact of sex and age in ethanol intoxication.

    Science.gov (United States)

    Binner, C; Selinski, S; Barysch, M J; Pölcher, C; Schormann, Wiebke; Hermes, Matthias; Brulport, Marc; Bauer, Alexander; Rudolph, Claudia; Bedawy, Essam; Schug, Markus; Golka, Klaus; Hasenclever, D; Trauer, H; Lessig, R; Bolt, H M; Ickstadt, K; Hengstler, Jan Georg

    2008-12-01

    Approximately 5,000 of 6 million annual visitors of the Oktoberfest in Munich have to undergo medical treatment. Patients with alcohol intoxication without trauma or further complications are all treated in a specialized medical camp. We studied these patients in order to identify risk factors and to assess the relevance of the Glasgow Coma Score (GCS) and of ethanol blood concentrations for patient management. In 2004 totally 405 patients suffering from ethanol intoxication without trauma were treated in the medical camp. A complete set of the following data was obtained from all 405 patients: GCS, ethanol blood concentration, age, sex, blood pressure (mean, systolic and diastolic), body temperature, heart rate, blood sugar, GOT, gamma-GT, and CK. A multivariate logistic regression model was applied to identify risk factors predicting patients at increased risk of hospitalization. Low GCS (8, OR: 4.18, CI: 1.96-8.65) low age (20-29 vs. > or =30 years, OR: 2.35, CI: 1.05-5.65) and male gender (male vs. female, OR: 3.58, CI: 1.36-9.34) independently predicted patients that had to be hospitalized. All other parameters including ethanol blood concentrations were not explanatory. Patients with GCS 8 (P < 0.001), suggesting that this subgroup may require longer recovery periods. Men aged 20-29 years were at highest risk for hospital admission. Increased risk could not be explained by higher ethanol blood concentrations in this subgroup. Importantly, GCS < 6 does not justify endotracheal intubation in ethanol intoxicated patients, when further complications, such as trauma, can be excluded.

  7. Expression of porcine endogenous retroviruses (PERVs) in melanomas of Munich miniature swine (MMS) Troll.

    Science.gov (United States)

    Dieckhoff, Britta; Puhlmann, Jenny; Büscher, Kristina; Hafner-Marx, Angela; Herbach, Nadja; Bannert, Norbert; Büttner, Mathias; Wanke, Rüdiger; Kurth, Reinhard; Denner, Joachim

    2007-07-20

    Porcine endogenous retroviruses (PERVs) are integrated in the genome of all pig breeds. Since some of them are able to infect human cells, they might represent a risk for xenotransplantation using pig cells or organs. However, the expression and biological role of PERVs in healthy pigs as well as in porcine tumours is largely unknown. Since we and others have recently shown overexpression of a human endogenous retrovirus, HERV-K, in human melanomas, we studied the expression of PERVs in melanomas of selectively bred Munich miniature swine (MMS) Troll. This breeding herd of MMS Troll is characterised by a high prevalence of melanomas, which histologically resemble various types of cutaneous melanomas in humans. Several genetic factors have been defined when studying inheritance of melanomas and melanocytic nevi in MMS Troll. Here we show that the polytropic PERV-A and PERV-B as well as the ecotropic PERV-C are present in the genome of all melanoma bearing MMS Troll investigated. Most interestingly, in the spleen, but not in other organs, recombinant PERV-A/C proviruses were found. PERV expression was found elevated in melanomas when compared to normal skin and viral proteins were expressed in melanomas and pulmonary metastasis-derived melanoma cell cultures. During passaging of these cells in vitro the expression of PERV mRNA and protein increased and virus particles were released as shown by RT activity in the supernatant and by electron microscopy. Genomic RNA of PERV-A, -B and -C were found in pelleted virus particles. Although PERV expression was elevated in melanomas and pulmonary metastasis-derived cell cultures, the function of the virus in tumour development is still unclear.

  8. Mass spectrometry with accelerators.

    Science.gov (United States)

    Litherland, A E; Zhao, X-L; Kieser, W E

    2011-01-01

    As one in a series of articles on Canadian contributions to mass spectrometry, this review begins with an outline of the history of accelerator mass spectrometry (AMS), noting roles played by researchers at three Canadian AMS laboratories. After a description of the unique features of AMS, three examples, (14)C, (10)Be, and (129)I are given to illustrate the methods. The capabilities of mass spectrometry have been extended by the addition of atomic isobar selection, molecular isobar attenuation, further ion acceleration, followed by ion detection and ion identification at essentially zero dark current or ion flux. This has been accomplished by exploiting the techniques and accelerators of atomic and nuclear physics. In 1939, the first principles of AMS were established using a cyclotron. In 1977 the selection of isobars in the ion source was established when it was shown that the (14)N(-) ion was very unstable, or extremely difficult to create, making a tandem electrostatic accelerator highly suitable for assisting the mass spectrometric measurement of the rare long-lived radioactive isotope (14)C in the environment. This observation, together with the large attenuation of the molecular isobars (13)CH(-) and (12)CH 2(-) during tandem acceleration and the observed very low background contamination from the ion source, was found to facilitate the mass spectrometry of (14)C to at least a level of (14)C/C ~ 6 × 10(-16), the equivalent of a radiocarbon age of 60,000 years. Tandem Accelerator Mass Spectrometry, or AMS, has now made possible the accurate radiocarbon dating of milligram-sized carbon samples by ion counting as well as dating and tracing with many other long-lived radioactive isotopes such as (10)Be, (26)Al, (36)Cl, and (129)I. The difficulty of obtaining large anion currents with low electron affinities and the difficulties of isobar separation, especially for the heavier mass ions, has prompted the use of molecular anions and the search for alternative

  9. Vaccination: Developing and implementing a competency-based-curriculum at the Medical Faculty of LMU Munich

    Science.gov (United States)

    Vogel, B.; Reuter, S.; Taverna, M.; Fischer, M. R.; Schelling, J.

    2016-01-01

    Background: In Germany medical students should gain proficiency and specific skills in the vaccination field. Especially important is the efficient communication of scientific results about vaccinations to the community, in order to give professional counseling with a complete overview about therapeutic options. Aim of the project: The aim of this project is to set up a vaccination-related curriculum in the Medical Faculty at the Ludwig-Maximilians-University in Munich. The structure of the curriculum is based on the National catalogue for competency-based learning objectives in the field of vaccination (Nationaler Kompetenzbasierter Lernzielekatalog Medizin NKLM). Through this curriculum, the students will not only acquire the classical educational skills concerning vaccination in theory and practice, but they will also learn how to become independent in the decision-making process and counseling. Moreover, the students will become aware of consequences of action related to this specific topic. Methods: According to defined guidelines, an analysis was performed on courses, which are currently offered by the university. A separate analysis of the NKLM was carried out. Both analyses identified the active courses related to the topic of vaccination as well as the NKLM learning objectives. The match between the topics taught in current courses and the NKLM learning objectives identified gaps concerning the teaching of specific content. Courses were modified in order to implement the missing NKLM learning objectives. Results: These analyses identified 24 vaccination-related courses, which are currently taught at the University. Meanwhile, 35 learning objectives on vaccination were identified in the NKLM catalogue. Four of which were identified as not yet part of the teaching program. In summary, this interdisciplinary work enabled the development of a new vaccination-related curriculum, including 35 learning objectives, which are now implemented in regular teaching

  10. Vaccination: Developing and implementing a competency-based-curriculum at the Medical Faculty of LMU Munich

    Directory of Open Access Journals (Sweden)

    Vogel, B.

    2016-02-01

    Full Text Available Background: In Germany medical students should gain proficiency and specific skills in the vaccination field. Especially important is the efficient communication of scientific results about vaccinations to the community, in order to give professional counseling with a complete overview about therapeutic options.Aim of the project: The aim of this project is to set up a vaccination-related curriculum in the Medical Faculty at the Ludwig-Maximilians-University in Munich. The structure of the curriculum is based on the National catalogue for competency-based learning objectives in the field of vaccination (Nationaler Kompetenzbasierter Lernzielekatalog Medizin NKLM. Through this curriculum, the students will not only acquire the classical educational skills concerning vaccination in theory and practice, but they will also learn how to become independent in the decision-making process and counseling. Moreover, the students will become aware of consequences of action related to this specific topic.Methods: According to defined guidelines, an analysis was performed on courses, which are currently offered by the university. A separate analysis of the NKLM was carried out. Both analyses identified the active courses related to the topic of vaccination as well as the NKLM learning objectives. The match between the topics taught in current courses and the NKLM learning objectives identified gaps concerning the teaching of specific content. Courses were modified in order to implement the missing NKLM learning objectives.Results: These analyses identified 24 vaccination-related courses, which are currently taught at the University. Meanwhile, 35 learning objectives on vaccination were identified in the NKLM catalogue. Four of which were identified as not yet part of the teaching program. In summary, this interdisciplinary work enabled the development of a new vaccination-related curriculum, including 35 learning objectives, which are now implemented in

  11. Bioindication with tobacco plants and grass culture at a long-term station in the city of Munich, Germany

    Energy Technology Data Exchange (ETDEWEB)

    Koehler, J. [Schloss Steinenhausen, Kulmbach (Germany). Aussenstelle Nordbayern; Peichl, L. [LfU Augsburg (Germany)

    2002-07-01

    At Bavarian long-term stations, biomonitoring of ozone and metal air pollution is carried out with tobacco plants and standardised grass culture. The stations provide background data of the city of Munich and of typical rural regions. The percentage of damaged leaf area of tobacco plants is definitely lower at the city station than at the rural stations, because there is more reduction potential (NO{sub x}) in the city. In standardised grass culture, the contents of metals specific for traffic emissions are higher at the city station, whereas the accumulation of other metals is in the same range like at all background stations. (orig.)

  12. Comprehensive multiresidue method for the simultaneous determination of 74 pesticides and metabolites in traditional Chinese herbal medicines by accelerated solvent extraction with high-performance liquid chromatography/tandem mass spectrometry.

    Science.gov (United States)

    Jia, Zhengwei; Mao, Xiuhong; Chen, Ke; Wang, Ke; Ji, Shen

    2010-01-01

    In this paper, a multiresidue method for the simultaneous target analysis of 74 pesticides and metabolites in traditional Chinese herbal medicines (TCHMs) was developed using accelerated solvent extraction (ASE) coupled with HPLC/MS/MS. Pesticide residues were extracted from the different samples using ASE, then purified by gel permeation chromatography and graphitized carbon black/primary, secondary amine SPE. Gradient elution was used in conjunction with positive mode electrospray ionization MS/MS to detect 74 pesticides and metabolites from Cortex Cinnamomi, Flos Carthami, Folium Ginkgo, Herba Pogostemonis, Radix Ginseng, and Semen Ginkgo using a single chromatographic run. The analytical performance was demonstrated by the analysis of extracts spiked at three concentration levels ranging from 0.005 to 0.125 mg/kg for each pesticide and metabolite. In general, recoveries ranging from 70 to 110%, with RSDs better than 15%, were obtained. The recovery and repeatability data were in good accordance with European Union guidelines for pesticide residue analysis. The LOD for most of the targeted pesticides and metabolites tested was below 0.01 mg/kg.

  13. JAERI TANDEM annual report 2000. April 1, 2000 - March 31, 2001

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, Suehiro; Ikezoe, Hiroshi; Chiba, Satoshi; Nagame, Yuichiro; Sataka, Masao; Iwamoto, Akira [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment] (eds.)

    2001-11-01

    This annual report describes research activities which have been performed with the JAERI tandem accelerator and the Van de Graaff accelerator from April 1, 2000 to March 31, 2001. Summary reports of 46 papers, and lists of publication, personnel and cooperative research with universities are contained. (author)

  14. JAERI tandem annual report 1999. April 1, 1999 - March 31, 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-11-01

    This annual report describes research activities which have been performed with the JAERI tandem accelerator and the Van de Graaff accelerator from April 1, 1999 to March 31, 2000. Summary reports of 49 papers, and lists of publication, personnel and cooperative research with universities are contained. (author)

  15. JAERI TANDEM and V.D.G. annual report 1996. April 1, 1996 - March 31, 1997

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, Suehiro; Ikezoe, Hiroshi; Iwamoto, Akira; Sataka, Masao; Nagame, Yuichiro; Shoji, Tokio; Okabe, Takashi; Maekawa, Hiroshi [eds.] [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1997-09-01

    This annual report describes research activities which have been performed with the JAERI tandem accelerator and the Van de Graaf accelerator from April 1, 1996 to March 31, 1997. Summary reports of 48 papers, and list of publications, personnel and cooperative researches with universities are contained. (author)

  16. JAERI tandem annual report 2001. April 1, 2001 - March 31, 2002

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, Suehiro; Ikezoe, Hiroshi; Chiba, Satoshi; Nagame, Yuichiro; Sataka, Masao; Iwamoto, Akira (eds.) [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2002-11-01

    This annual report describes research activities which have been performed with the JAERI tandem accelerator and the Van de Graaff accelerator from April 1, 2001 to March 31, 2002. Summary reports of 48 papers, and lists of publication, personnel and cooperative research with universities are contained. (author)

  17. JAERI TANDEM and V.D.G. annual report 1994. April 1, 1994 - March 31, 1995

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Yasuo; Ikezoe, Hiroshi; Iwamoto, Akira; Sataka, Masao; Shinohara, Nobuo; Takeuchi, Suehiro; Shoji, Tokio; Okabe, Takashi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment] [eds.

    1995-10-01

    This annual report describes research activities which have been performed with the JAERI tandem accelerator and the Van de Graaff accelerator from April 1, 1994 to March 31, 1995. Summary reports of 47 papers, and list of publications, personnel and cooperative researches with universities are contained. (author).

  18. JAERI TANDEM and V.D.G. annual report 1995. April 1, 1995 - March 31, 1996

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, Suehiro; Ikezoe, Hiroshi; Iwamoto, Akira; Sataka, Masao; Nagame, Yuichiro; Shoji, Tokio; Okabe, Takashi; Maekawa, Hiroshi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment] [eds.

    1996-08-01

    This annual report describes research activities which have been performed with the JAERI Tandem accelerator and the Van de Graaff accelerator from April 1, 1995 to March 31, 1996. Summary reports of 59 papers, and list of publications, personnel and cooperative researches with universities are contained. (author)

  19. JAERI tandem and V.D.G. annual report 1997. April 1, 1997 - March 31, 1998

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, Suehiro; Ikezoe, Hiroshi; Chiba, Satoshi; Sataka, Masao; Nagame, Yuichiro; Takemori, Satoshi; Iwamoto, Akira [eds.] [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-10-01

    This annual report describes research activities which have been performed with the JAERI tandem accelerator and the Van de Graaff accelerator from April 1, 1997 to March 31, 1998. Summary reports of 40 papers, and lists of publication, personnel and cooperative researches with universities are contained. (author)

  20. JAERI tandem and V.D.G. annual report 1998. April 1, 1998 - March 31, 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-12-01

    This annual report describes research activities which have been performed with the JAERI tandem accelerator and the Van de Graaff accelerator from April 1, 1998 to March 31, 1999. Summary reports of 38 papers, and lists of publication, personnel and cooperative research with universities and contained. (author)

  1. Return to play after thigh muscle injury in elite football players: implementation and validation of the Munich muscle injury classification

    Science.gov (United States)

    Ekstrand, Jan; Askling, Carl; Magnusson, Henrik; Mithoefer, Kai

    2013-01-01

    Background Owing to the complexity and heterogeneity of muscle injuries, a generally accepted classification system is still lacking. Aims To prospectively implement and validate a novel muscle injury classification and to evaluate its predictive value for return to professional football. Methods The recently described Munich muscle injury classification was prospectively evaluated in 31 European professional male football teams during the 2011/2012 season. Thigh muscle injury types were recorded by team medical staff and correlated to individual player exposure and resultant time-loss. Results In total, 393 thigh muscle injuries occurred. The muscle classification system was well received with a 100% response rate. Two-thirds of thigh muscle injuries were classified as structural and were associated with longer lay-off times compared to functional muscle disorders (pinjuries) with increasing lay-off time associated with more severe structural injury. Median lay-off time of functional disorders was 5–8 days without significant differences between subgroups. There was no significant difference in the absence time between anterior and posterior thigh injuries. Conclusions The Munich muscle classification demonstrates a positive prognostic validity for return to play after thigh muscle injury in professional male football players. Structural injuries are associated with longer average lay-off times than functional muscle disorders. Subclassification of structural injuries correlates with return to play, while subgrouping of functional disorders shows less prognostic relevance. Functional disorders are often underestimated clinically and require further systematic study. PMID:23645834

  2. The reform of the continuation schools in Munich and the establishment of the dual system in vocational education

    Directory of Open Access Journals (Sweden)

    Ilić-Rajković Aleksandra

    2015-01-01

    Full Text Available The reform of vocational education in Serbia is focused on the introduction of the so called dual system. The current form of this system originates from the reforms of the continuation schools in Germany near the end of the nineteenth century. The paper presents the reform of these schools led by Georg Kerschensteiner, one of the founders of the dual system. The first part of the article is devoted to a wider economic and social context in Germany at the end of the nineteenth century and the problem of the working - class young people, which led to the educational reform. The central part of the paper considers the reform of the continuation schools in Munich from the theoretical aspect and the aspect of the realization. The main goal of education in continuation schools, according to Kerschensteiner's pedagogic concept is the development of moral character of students, future citizens. The goal was to be achieved through three tasks in the domain of education: individual, social and civic education. The realization of the reform was analyzed from the perspective of the organization of teaching, and the roles of the participants: students, teachers, employers and municipalities. The end of the paper gives an account of the effects of the reform and public discussions initiated on that occasion. The conclusion stresses the importance of studying the Munich's reform and Kerschensteiner's pedagogic concept especially in those countries where the reform of vocational education is planned.

  3. Reevaluation of microplastics extraction efficiency with the aim of Munich Plastic Sediment Separator.

    Science.gov (United States)

    Zobkov, Mikhail; Esiukova, Elena; Grave, Aleksei; Khatmullina, Liliya

    2017-04-01

    Invading of microplastics into marine environment is known as a global ecological threat. Specific density of microplastics can vary significantly depending on a polymer type, technological processes of its production, additives, weathering, and biofouling. Plastic particles can sink or float on the sea surface, but with time, most of drifting plastics become negatively buoyant and sink to the sea floor due to biofouling or adherence of denser particles. As a result, the seabed becomes the ultimate repository for microplastic particles and fibres. A study of microplastics content in aquatic sediments is an important source of information about ways of their migration, sink and accumulation zones. The Munich Plastic Sediment Separator (MPSS), proposed by Imhoff et al. (2012), is considered as the most effective tool for microplastic extraction. However, we observed that the numbers of marine microplastics extracted with this tool from different kinds of bottom sediments were significantly underestimated. We examined the extraction efficiency of the MPSS by adding artificial reference particles (ARPs) to marine sediment sample before the extraction procedure. Extraction was performed by two different methods: the modified NOAA method and using the MPSS. The separation solution with specific density 1.5 g/ml was used. Subsequent cleaning, drying and microscope detection procedures were identical. The microplastics content was determined in supernatant fraction, in the bulk of the extraction solution, in spoil dump fraction of MPSS and in instrument wash-out. While the extraction efficiency from natural sediments of ARPs by the MPSS was really high (100% in most cases), the extraction efficiency of marine microplastics was up to 10 times lower than that obtained with modified NOAA method for the same samples. Less than 40% of the total marine microplastics content has been successfully extracted with the MPSS. Large amounts of marine microplastics were found in the

  4. Particulate matter in the indoor air of classrooms—exploratory results from Munich and surrounding area

    Science.gov (United States)

    Fromme, H.; Twardella, D.; Dietrich, S.; Heitmann, D.; Schierl, R.; Liebl, B.; Rüden, H.

    Numerous epidemiological studies have demonstrated the association between particle mass (PM) concentration in outside air and the occurrence of health related problems and/or diseases. However, much less is known about indoor PM concentrations and associated health risks. In particular, data are needed on air quality in schools, since children are assumed to be more vulnerable to health hazards and spend a large part of their time in classrooms. On this background, we evaluated indoor air quality in 64 schools in the city of Munich and a neighbouring district outside the city boundary. In winter 2004-2005 in 92 classrooms, and in summer 2005 in 75 classrooms, data on indoor air climate parameters (temperature, relative humidity), carbon dioxide (CO 2) and various dust particle fractions (PM 10, PM 2.5) were collected; for the latter both gravimetrical and continuous measurements by laser aerosol spectrometer (LAS) were implemented. In the summer period, the particle number concentration (PNC), was determined using a scanning mobility particle sizer (SMPS). Additionally, data on room and building characteristics were collected by use of a standardized form. Only data collected during teaching hours were considered in analysis. For continuously measured parameters the daily median was used to describe the exposure level in a classroom. The median indoor CO 2 concentration in a classroom was 1603 ppm in winter and 405 ppm in summer. With LAS in winter, median PM concentrations of 19.8 μg m -3 (PM 2.5) and 91.5 μg m -3 (PM 10) were observed, in summer PM concentrations were significantly reduced (median PM 2.5=12.7 μg m -3, median PM 10=64.9 μg m -3). PM 2.5 concentrations determined by the gravimetric method were in general higher (median in winter: 36.7 μg m -3, median in summer: 20.2 μg m -3) but correlated strongly with the LAS-measured results. In explorative analysis, we identified a significant increase of LAS-measured PM 2.5 by 1.7 μg m -3 per increase

  5. Bifacial tandem solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Wojtczuk, Steven J.; Chiu, Philip T.; Zhang, Xuebing; Gagnon, Edward; Timmons, Michael

    2016-06-14

    A method of fabricating on a semiconductor substrate bifacial tandem solar cells with semiconductor subcells having a lower bandgap than the substrate bandgap on one side of the substrate and with subcells having a higher bandgap than the substrate on the other including, first, growing a lower bandgap subcell on one substrate side that uses only the same periodic table group V material in the dislocation-reducing grading layers and bottom subcells as is present in the substrate and after the initial growth is complete and then flipping the substrate and growing the higher bandgap subcells on the opposite substrate side which can be of different group V material.

  6. [Antibiotic consumption surveillance - state of implementation in Munich hospitals : Latest survey by the Munich public health department on the implementation of § 23 Infection protection act].

    Science.gov (United States)

    Otto, Cornelia; Hirl, Bertrand; Schweitzer, Stefan; Gleich, Sabine

    2016-12-01

    On 4 August 2011 a modification of the infection protection act became law, meaning that antibiotic consumption surveillance and evaluation of data on the local resistance situation became obligatory for hospitals. Four years after the modification of the infection protection act became law, the Munich public health department aimed to evaluate the state of implementation of antibiotic consumption surveillance in Munich hospitals and to ascertain which antibiotic stewardship (ABS) structures have already been established. A questionnaire was sent to Munich hospitals about their antibiotic management structural data and state of implementation of legal requirements. Only 32 % of the hospitals have qualified ABS-experts available. In 76 % of the hospitals persons responsible for antibiotic consumption surveillance are appointed, while in 12 % persons responsible for antibiotic consumption surveillance are at least partly released from their normal work for this activity. Twenty-one hospitals (21 %) conduct antibiotic consumption surveillance taking into account all antiinfective agents mentioned in the Robert Koch-Institute (RKI) guidelines. Of these, 19 (76 %) did this on basis of World Health Organizations ATC/DDD-system (anatomical therapeutic chemical [ATC] classification system which uses defined daily doses [DDD]). The data on antibiotic consumption is evaluated in 72 % of the hospitals, 68 % take account of the local resistance situation. In 96 %, in-house lists of antiinfectives are available; in 80 %, in-house guidelines for antibiotic treatment are available. Fourty-four percent of the hospitals take part in a national surveillance. For the first time data were collected on implementation of antibiotic consumption surveillance in hospitals, which has been required by law since 2011. An incomplete implementation of legal requirements was demonstrated. It was found that structural and personnel prerequisites are often missing, that

  7. Future accelerators (?)

    Energy Technology Data Exchange (ETDEWEB)

    John Womersley

    2003-08-21

    I describe the future accelerator facilities that are currently foreseen for electroweak scale physics, neutrino physics, and nuclear structure. I will explore the physics justification for these machines, and suggest how the case for future accelerators can be made.

  8. A New Accelerator-Based Mass Spectrometry.

    Science.gov (United States)

    Gove, H. E.

    1983-01-01

    Tandem electrostatic accelerators produce beams of positive ions which are used to penetrate atomic nuclei in a target, inducing nuclear reactions whose study elucidates varied properties of the nucleus. Uses of the system, which acts like a mass spectrometer, are discussed. These include radiocarbon dating measurements. (JN)

  9. Report on the ESO/MPA/MPE/Excellence Cluster/LMU and TUM Munich Joint Conference ''Discs in Galaxies''

    Science.gov (United States)

    Ellis, R.

    2016-09-01

    The annual Munich Joint Astronomy Conference brought together observers and theorists studying the full range of cosmic environments and epochs where discs play a role in shaping the structural assembly history of galaxies. Considerable progress is being made in interpreting the past history of the Milky Way and Andromeda through massive stellar imaging and spectroscopic campaigns. This is being augmented with interferometric studies of gaseous discs in nearby galaxies with exquisite angular resolution. Integral field spectrographs are providing resolved data for star-forming and quiescent galaxies to redshifts of three. This explosion of new data is being interpreted with high resolution numerical simulations in order to understand the physical processes which govern the stability, formation and disruption of early discs, and how star formation is regulated in the context of various feedback processes. Selected highlights of the progress reported at the conference are presented.

  10. Motivations to visit the Oktoberfest in Blumenau (BR and Munich (Germany: A comparative analysis using the Partial Least Squares technique

    Directory of Open Access Journals (Sweden)

    Sérgio Luiz do Amaral Moretti

    2016-05-01

    Full Text Available It is impossible to develop effective tourism marketing actions and planning the communication without an understanding of the motivations of tourists for travel. The aim of this paper is to deepen the knowledge of the reasons for traveling festivals visitors. For this purpose we developed a survey instrument that consists of four constructs obtained in the literature, with data collected through a survey in Oktoberfest Blumenau (BR, with 432 respondents and Munich (Germany, with 285 respondents. Most of scales were confirmed showing the validity of the instrument. The study by Partial Least Squares - PLS revealed that both samples looking to experience different customs and cultures and meet new situations that are not part of your environment. Visitors also attend festivals to be with friends, reduce stress, anxiety and frustration. The understanding of tourists' motivations for travel reports new subsidies for the development of public policies and the tourist trade.

  11. Concentrations and source contributions of particulate organic matter before and after implementation of a low emission zone in Munich, Germany.

    Science.gov (United States)

    Qadir, R M; Abbaszade, G; Schnelle-Kreis, J; Chow, J C; Zimmermann, R

    2013-04-01

    Within the Munich low emission zone (LEZ), samples of PM(2.5) were collected before (2006/2007) and after (2009/2010) the implementation of the LEZ. The samples were analyzed for carbon fraction (EC/OC) and particulate organic compounds (POC). Significant lower concentrations were noticed for elemental carbon (EC) and some of the POC like vanillic acid, acetosyringone, syringylacetone and syringic acid after the implementation of the LEZ. Higher concentrations of levoglucosan, retene and O-PAH were detected in the second sampling period. Positive matrix factorization (PMF) was used to identify the main sources of POC. Emissions from traffic, solid fuels combustion, cooking and mixed source were separated. The contribution of traffic source factor was decreased about 60% after the implementation of the LEZ. Thus the average concentration of EC from traffic factor decreased from 1.1 to 0.5 μg/m(3) after the implementation of the LEZ.

  12. Munich Re konsultant Gerhard Berz : katastroofid on meie ärile kasulikud / Gerhard Berz ; interv. Ulrich Schnabel, tõlk. Erik Aru

    Index Scriptorium Estoniae

    Berz, Gerhard

    2005-01-01

    Intervjuu meteoroloogiga, kes on kolm aastakümmet arvutanud edasikindlustusfirma Munich Re heaks loodusõnnetuste riske ja viibinud ligi viiekümnes katastroofipiirkonnas. Vaatamata sellele, et 2004. aasta oli kõige kulukamate looduskatastroofide aasta, saavutas firma läbi aegade parimad majandustulemused. Lisa: Meeletu kahju

  13. Spix and Wagler type specimens of reptiles and amphibians in the Natural History Musea in Munich (Germany) and Leiden (The Netherlands)

    NARCIS (Netherlands)

    Hoogmoed, M.S.; Gruber, U.

    1983-01-01

    An evaluation of the existing SPIX/WAGLER type material in the museums in Munich and Leiden is given. It transpired that a considerable part of the type material, which was thought to have been destroyed during the second world war, is still extant. The material is described briefly, its presenttaxo

  14. Transepithelial water and urea permeabilities of isolated perfused Munich-Wistar rat inner medullary thin limbs of Henle's loop.

    Science.gov (United States)

    Nawata, C Michele; Evans, Kristen K; Dantzler, William H; Pannabecker, Thomas L

    2014-01-01

    To better understand the role that water and urea fluxes play in the urine concentrating mechanism, we determined transepithelial osmotic water permeability (Pf) and urea permeability (Purea) in isolated perfused Munich-Wistar rat long-loop descending thin limbs (DTLs) and ascending thin limbs (ATLs). Thin limbs were isolated either from 0.5 to 2.5 mm below the outer medulla (upper inner medulla) or from the terminal 2.5 mm of the inner medulla. Segment types were characterized on the basis of structural features and gene expression levels of the water channel aquaporin 1, which was high in the upper DTL (DTLupper), absent in the lower DTL (DTLlower), and absent in ATLs, and the Cl-(1) channel ClCK1, which was absent in DTLs and high in ATLs. DTLupper Pf was high (3,204.5 ± 450.3 μm/s), whereas DTLlower showed very little or no osmotic Pf (207.8 ± 241.3 μm/s). Munich-Wistar rat ATLs have previously been shown to exhibit no Pf. DTLupper Purea was 40.0 ± 7.3 × 10(-5) cm/s and much higher in DTLlower (203.8 ± 30.3 × 10(-5) cm/s), upper ATL (203.8 ± 35.7 × 10(-5) cm/s), and lower ATL (265.1 ± 49.8 × 10(-5) cm/s). Phloretin (0.25 mM) did not reduce DTLupper Purea, suggesting that Purea is not due to urea transporter UT-A2, which is expressed in short-loop DTLs and short portions of some inner medullary DTLs close to the outer medulla. In summary, Purea is similar in all segments having no osmotic Pf but is significantly lower in DTLupper, a segment having high osmotic Pf. These data are inconsistent with the passive mechanism as originally proposed.

  15. The Utrecht accelerator facility for precision dating with radionuclides

    NARCIS (Netherlands)

    Borg, K. van der; Alderliesten, C.; Haitjema, H.; Hut, G.; Zwol, N.A. van

    1984-01-01

    The Utrecht facility for accelerator mass spectrometry is described. The set-up with an EN tandem accelerator is designed for measurements of a broad range of long-lived radionuclides and of stable trace elements. In particular, dating measurements with 10Be and 14C can be performed with high precis

  16. Accelerator mass spectrometry.

    Science.gov (United States)

    Hellborg, Ragnar; Skog, Göran

    2008-01-01

    In this overview the technique of accelerator mass spectrometry (AMS) and its use are described. AMS is a highly sensitive method of counting atoms. It is used to detect very low concentrations of natural isotopic abundances (typically in the range between 10(-12) and 10(-16)) of both radionuclides and stable nuclides. The main advantages of AMS compared to conventional radiometric methods are the use of smaller samples (mg and even sub-mg size) and shorter measuring times (less than 1 hr). The equipment used for AMS is almost exclusively based on the electrostatic tandem accelerator, although some of the newest systems are based on a slightly different principle. Dedicated accelerators as well as older "nuclear physics machines" can be found in the 80 or so AMS laboratories in existence today. The most widely used isotope studied with AMS is 14C. Besides radiocarbon dating this isotope is used in climate studies, biomedicine applications and many other fields. More than 100,000 14C samples are measured per year. Other isotopes studied include 10Be, 26Al, 36Cl, 41Ca, 59Ni, 129I, U, and Pu. Although these measurements are important, the number of samples of these other isotopes measured each year is estimated to be less than 10% of the number of 14C samples.

  17. Covalently linked tandem lesions in DNA.

    Science.gov (United States)

    Patrzyc, Helen B; Dawidzik, Jean B; Budzinski, Edwin E; Freund, Harold G; Wilton, John H; Box, Harold C

    2012-12-01

    Reactive oxygen species (ROS) generate a type of DNA damage called tandem lesions, two adjacent nucleotides both modified. A subcategory of tandem lesions consists of adjacent nucleotides linked by a covalent bond. Covalently linked tandem lesions generate highly characteristic liquid chromotography-tandem mass spectrometry (LC-MS/MS) elution profiles. We have used this property to comprehensively survey X-irradiated DNA for covalently linked tandem lesions. A total of 15 tandem lesions were detected in DNA irradiated in deoxygenated aqueous solution, five tandem lesions were detected in DNA that was irradiated in oxygenated solution.

  18. Accelerating Value Creation with Accelerators

    DEFF Research Database (Denmark)

    Jonsson, Eythor Ivar

    2015-01-01

    accelerator programs. Microsoft runs accelerators in seven different countries. Accelerators have grown out of the infancy stage and are now an accepted approach to develop new ventures based on cutting-edge technology like the internet of things, mobile technology, big data and virtual reality. It is also...... with the traditional audit and legal universes and industries are examples of emerging potentials both from a research and business point of view to exploit and explore further. The accelerator approach may therefore be an Idea Watch to consider, no matter which industry you are in, because in essence accelerators...

  19. Accelerating Value Creation with Accelerators

    DEFF Research Database (Denmark)

    Jonsson, Eythor Ivar

    2015-01-01

    Accelerators can help to accelerate value creation. Accelerators are short-term programs that have the objective of creating innovative and fast growing ventures. They have gained attraction as larger corporations like Microsoft, Barclays bank and Nordea bank have initiated and sponsored accelera......Accelerators can help to accelerate value creation. Accelerators are short-term programs that have the objective of creating innovative and fast growing ventures. They have gained attraction as larger corporations like Microsoft, Barclays bank and Nordea bank have initiated and sponsored...... an approach to facilitate implementation and realization of business ideas and is a lucrative approach to transform research into ventures and to revitalize regions and industries in transition. Investors have noticed that the accelerator approach is a way to increase the possibility of success by funnelling...

  20. Materials science symposium 'heavy ion science in tandem energy region'

    Energy Technology Data Exchange (ETDEWEB)

    Iwamoto, Akira; Yoshida, Tadashi; Takeuchi, Suehiro [eds.

    2000-01-01

    The tandem accelerator established at Japan Atomic Energy Research Institute (JAERI) in 1982 has been one of the most prominent electrostatic accelerators in the world. The accelerator has been serving for many researches planned by not only JAERI staff but also researchers of universities and national institutes. After the completion of the tandem booster in 1993, four times higher beam energy became available. These two facilities, the tandem accelerator and the booster, made great strides in heavy ion physics and a lot of achievements have been accumulated until now. The research departments of JAERI were reformed in 1998, and the accelerators section came under the Department of Materials Science. On this reform of the research system, the symposium 'Heavy Ion Science in Tandem Energy Region' was held in cooperation with nuclear and solid state physicists although there has been no such symposium for many years. The symposium was expected to stimulate novel development in both nuclear and solid state physics, and also interdisciplinary physics between nuclear and solid state physics. The 68 papers are indexed individually. (J.P.N.)

  1. Tandem Cylinder Noise Predictions

    Science.gov (United States)

    Lockhard, David P.; Khorrami, Mehdi R.; CHoudhari, Meelan M.; Hutcheson, Florence V.; Brooks, Thomas F.; Stead, Daniel J.

    2007-01-01

    In an effort to better understand landing-gear noise sources, we have been examining a simplified configuration that still maintains some of the salient features of landing-gear flow fields. In particular, tandem cylinders have been studied because they model a variety of component level interactions. The present effort is directed at the case of two identical cylinders spatially separated in the streamwise direction by 3.7 diameters. Experimental measurements from the Basic Aerodynamic Research Tunnel (BART) and Quiet Flow Facility (QFF) at NASA Langley Research Center (LaRC) have provided steady surface pressures, detailed off-surface measurements of the flow field using Particle Image Velocimetry (PIV), hot-wire measurements in the wake of the rear cylinder, unsteady surface pressure data, and the radiated noise. The experiments were conducted at a Reynolds number of 166 105 based on the cylinder diameter. A trip was used on the upstream cylinder to insure a fully turbulent shedding process and simulate the effects of a high Reynolds number flow. The parallel computational effort uses the three-dimensional Navier-Stokes solver CFL3D with a hybrid, zonal turbulence model that turns off the turbulence production term everywhere except in a narrow ring surrounding solid surfaces. The current calculations further explore the influence of the grid resolution and spanwise extent on the flow and associated radiated noise. Extensive comparisons with the experimental data are used to assess the ability of the computations to simulate the details of the flow. The results show that the pressure fluctuations on the upstream cylinder, caused by vortex shedding, are smaller than those generated on the downstream cylinder by wake interaction. Consequently, the downstream cylinder dominates the noise radiation, producing an overall directivity pattern that is similar to that of an isolated cylinder. Only calculations based on the full length of the model span were able to

  2. RECIRCULATING ACCELERATION

    Energy Technology Data Exchange (ETDEWEB)

    BERG,J.S.; GARREN,A.A.; JOHNSTONE,C.

    2000-04-07

    This paper compares various types of recirculating accelerators, outlining the advantages and disadvantages of various approaches. The accelerators are characterized according to the types of arcs they use: whether there is a single arc for the entire recirculator or there are multiple arcs, and whether the arc(s) are isochronous or non-isochronous.

  3. LIBO accelerates

    CERN Multimedia

    2002-01-01

    The prototype module of LIBO, a linear accelerator project designed for cancer therapy, has passed its first proton-beam acceleration test. In parallel a new version - LIBO-30 - is being developed, which promises to open up even more interesting avenues.

  4. Accelerating Inspire

    CERN Document Server

    AUTHOR|(CDS)2266999

    2017-01-01

    CERN has been involved in the dissemination of scientific results since its early days and has continuously updated the distribution channels. Currently, Inspire hosts catalogues of articles, authors, institutions, conferences, jobs, experiments, journals and more. Successful orientation among this amount of data requires comprehensive linking between the content. Inspire has lacked a system for linking experiments and articles together based on which accelerator they were conducted at. The purpose of this project has been to create such a system. Records for 156 accelerators were created and all 2913 experiments on Inspire were given corresponding MARC tags. Records of 18404 accelerator physics related bibliographic entries were also tagged with corresponding accelerator tags. Finally, as a part of the endeavour to broaden CERN's presence on Wikipedia, existing Wikipedia articles of accelerators were updated with short descriptions and links to Inspire. In total, 86 Wikipedia articles were updated. This repo...

  5. MEMS - Munich Energy Management System. FIA Project: Exchange of research information; MEMS - Muenchner Energiemanagement-System. FIA-Projekt - Forschungs-Informations-Austausch

    Energy Technology Data Exchange (ETDEWEB)

    Funk, H.; Fries, W.

    2001-10-01

    The City of Munich developed the project 'Munich Energy-Management-Systems (MEMS)' with financial support from the Federal Ministry of Economy and Technology. The project is based on a system of building automation using as many standard elements of hardware and software as possible. This will guarantee a high degree of independence from suppliers and subcontractors. The project has led to a reliable working base for the evaluation, measuring and control for ca. 150 municipal buildings. (orig.) [German] Mit dem Projekt 'Muenchner Energie-Management-System (MEMS)' erstellte die Landeshauptstadt Muenchen mit finanzieller Unterstuetzung des Bundesministeriums fuer Wirtschaft und Technologie ein auf der Leitzentrale Haustechnik (LZH) basierendes zentrales Energiemanagementsystem. Die Verwendung moeglichst vieler Standards in Hard- und Software ist dabei ein wesentlicher Gesichtspunkt. Dadurch wurde eine weitgehende Unabhaengigkeit von einem einzelnen Hersteller erreicht. Damit wurde ein Erfassungs-, Auswerte- und Steuerungssystem fuer derzeit rund 150 staedtische Gebaeude geschaffen. (orig.)

  6. Assessing the Recreation Value of Urban Woodland Using the Ecosystem Service Approach in Two Forests in the Munich Metropolitan Region

    Directory of Open Access Journals (Sweden)

    Gerd Lupp

    2016-11-01

    Full Text Available Recreation is considered an important ecosystem services (ES in urban woodlands and puts pressure on other ES. Visitor management strategies can be tools to safeguard biodiversity and ES. On-site data are necessary to evaluate the demand for outdoor recreation opportunities in urban woodlands, but also for providing more reliable values for monetization as a basis for multifunctional forest management, and for raising awareness for the importance of urban proximate forests. Such information can also be used for the assessment and monetization of socio-cultural ES, and hence, contribute to developing market-based mechanisms or to promoting these ES. In our paper, we demonstrate methods to describe recreational demand by collecting data from interviews and using camera traps in two forests in the north of Munich for visitor counting. Visitor numbers in the forests were much greater than rough estimations; visitors also had quite long travelling distances to the forests. Jogging or Nordic walking were proven to be important recreational activities. In some of the monitored locations, almost half of the recreationists carried out these sports. Depending on the method chosen, the calculative monetary value of recreation reached up to 15,440 Euro per hectare per year.

  7. Assessment of alcoholic standard drinks using the Munich composite international diagnostic interview (M-CIDI): An evaluation and subsequent revision.

    Science.gov (United States)

    Kuitunen-Paul, Sören; Rehm, Jürgen; Lachenmeier, Dirk W; Kadrić, Firdeus; Kuitunen, Paula T; Wittchen, Hans-Ulrich; Manthey, Jakob

    2017-09-01

    The quantity and frequency of alcohol consumption are crucial both in risk assessment as well as epidemiological and clinical research. Using the Munich Composite International Diagnostic Interview (M-CIDI), drinking amounts have been assessed in numerous large-scale studies. However, the accuracy of this assessment has rarely been evaluated. This study evaluates the relevance of drink categories and pouring sizes, and the factors used to convert actual drinks into standard drinks. We compare the M-CIDI to alternative drink assessment instruments and empirically validate drink categories using a general population sample (n = 3165 from Germany), primary care samples (n = 322 from Italy, n = 1189 from Germany), and a non-representative set of k = 22503 alcoholic beverages sold in Germany in 2010-2016. The M-CIDI supplement sheet displays more categories than other instruments (AUDIT, TLFB, WHO-CIDI). Beer, wine, and spirits represent the most prevalent categories in the samples. The suggested standard drink conversion factors were inconsistent for different pouring sizes of the same drink and, to a smaller extent, across drink categories. For the use in Germany and Italy, we propose the limiting of drink categories and pouring sizes, and a revision of the proposed standard drinks. We further suggest corresponding examinations and revisions in other cultures. © 2017 The Authors International Journal of Methods in Psychiatric Research Published by John Wiley & Sons Ltd.

  8. The Munich Near-Infrared Cluster Survey -- IV. Biases in the Completeness of Near-Infrared Imaging Data

    CERN Document Server

    Snigula, J; Bender, R; Botzler, C S; Feulner, G; Hopp, U

    2002-01-01

    We present the results of completeness simulations for the detection of point sources as well as redshifted elliptical and spiral galaxies in the K'-band images of the Munich Near-Infrared Cluster Survey (MUNICS). The main focus of this work is to quantify the selection effects introduced by threshold-based object detection algorithms used in deep imaging surveys. Therefore, we simulate objects obeying the well-known scaling relations between effective radius and central surface brightness, both for de Vaucouleurs and exponential profiles. The results of these simulations, while presented for the MUNICS project, are applicable in a much wider context to deep optical and near-infrared selected samples. We investigate the detection probability as well as the reliability for recovering the true total magnitude with Kron-like (adaptive) aperture photometry. The results are compared to the predictions of the visibility theory of Disney and Phillipps in terms of the detection rate and the lost-light fraction. Addit...

  9. Addiction research centres and the nurturing of creativity: IFT Institut für Therapieforschung in Munich, Germany.

    Science.gov (United States)

    Bühringer, Gerhard

    2014-08-01

    This paper describes the history and current structure of the Institut für Therapieforschung (IFT) [Institute for Therapy Research] in Munich, as well as major research topics and factors which might contribute to a creative structure and atmosphere for innovative research in the addiction field. The institute was founded in 1973 as a non-profit non-governmental organization (NGO) with a focus on applied research. Starting with behaviour therapy-based development and evaluation of programmes for alcohol, illicit drugs and smoking and the evaluation of treatment services, the institute gradually expanded its topics, covering prevention (1985) and epidemiology and policy evaluation (1990), and participated throughout this period in the development of guidelines and screening, diagnostic and clinical instruments. Later, the IFT tried to bridge the gap between basic sciences, applied research, health-care services and health policy, with a network of national and international contacts, including its own university engagements and collaborations with foreign research groups and national and European Union (EU) agencies. Possible creativity-promoting factors on the institutional and individual levels are discussed, e.g. the collaboration of experienced senior researchers with carefully selected innovative doctoral students, considerable in-house and external training of young researchers and the early participation and presentation of their work at international conferences, independence from stakeholders in the field and the refusal of project funds which require external clearance of publications.

  10. Design and Operation of Public Transport in Munich%慕尼黑公共交通的设计与运营

    Institute of Scientific and Technical Information of China (English)

    Guenter Pedall

    2007-01-01

    @@ Introduction of Public Transport in Munich Underground System The new generation of underground trains travel at a top speed of 80 km/h and are equipped with cutting-edge technology. Current projects rolling stock are equipped with Onboard Fire-Detection and Extinction of fire, viedo-surveillance-system with data communication in parking facilities, on board-TV(passenger information and entertainment) and passenger counting system.

  11. Geothermal models on different scales - understanding and geothermal characterization of a fault zone before simulating - a case study from the Munich region (Germany)

    Science.gov (United States)

    Dussel, Michael; Ortiz, Adrián; Thomas, Rüdiger; Schulz, Rüdiger

    2015-04-01

    A challenging task for geothermal exploration is the geothermal characterization of fault zones, which seems to play an important role for the exploration of the geothermal Malm Aquifer in the Munich region. The results of an actualized regional thermo-hydraulic model of the Munich region as well as flow-, temperature- and stress analysis for a more detailed local THM-model in the realm of a geothermal power plant are presented. Whereas the main focus of the actualized regional model lies in the forecast of potential temperature or hydraulic pressure interferences of geothermal doublet or triplet systems, the more detailed local model contributes to the understanding of flow, temperature distribution and induced microseismicity, which might occur during production or injection. The flow regime was described with the diagnostic plot derived from the analysis of pump tests. The temperature distribution in a well was modeled (Comsol). Joints and faults in a well were investigated to their reactivation potential in the recent stress field (slip-tendency analysis, GMI-software). Unfortunately only scarce data for geomechanical analysis are registered in the standard exploration scheme for geothermal wells in the Munich region, especially for determining the minimum horizontal stress. It is therefore highly recommended to extend the well measuring and logging program in the future.

  12. Horizontal Accelerator

    Data.gov (United States)

    Federal Laboratory Consortium — The Horizontal Accelerator (HA) Facility is a versatile research tool available for use on projects requiring simulation of the crash environment. The HA Facility is...

  13. Future accelerators

    CERN Document Server

    Hübner, K

    1999-01-01

    An overview of the various schemes for electron-positron linear colliders is given and the status of the development of key components and the various test facilities is given. The present studies of muon-muon colliders and very large hadron colliders are summarized including the plans for component development and tests. Accelerator research and development to achieve highest gradients in linear accelerators is outlined. (44 refs).

  14. ARAMIS; An ambidextrous 2 MV accelerator for IBA and MeV implantation

    Energy Technology Data Exchange (ETDEWEB)

    Cottereau, E.; Camplan, J.; Chaumont, J.; Meunier, R.; Bernas, H. (CSNSM, 91 - Orsay (France))

    1990-01-01

    We will present the 2 MV accelerator that we built at our laboratory. ARAMIS is a tandem accelerator with a positive-ion source in the high-voltage terminal so that it can be operated both in the tandem and in the single-ended mode. Tuning from one mode to the other is quite easy so that the implantation or irradiation of samples can be followed periodically with RBS. We show some results. (orig.).

  15. ARAMIS: An ambidextrous 2 MV accelerator for IBA and MeV implantation

    Science.gov (United States)

    Cottereau, E.; Camplan, J.; Chaumont, J.; Meunier, R.; Bernas, H.

    1990-01-01

    We will present the 2 MV accelerator that we built at our laboratory. ARAMIS is a tandem accelerator with a positive-ion source in the high-voltage terminal so that it can be operated both in the tandem and in the single-ended mode. Tuning from one mode to the other is quite easy so that the implantation or irradiation of samples can be followed periodically with RBS. We show some results.

  16. Asymmetric tandem organic solar cells

    Science.gov (United States)

    Howells, Thomas J.

    Organic photovoltaics (OPVs) is an area that has attracted much attention recently as a potential low cost, sustainable source of energy with a good potential for full-scale commercialisation. Understanding the factors that determine the efficiency of such cells is therefore a high priority, as well as developing ways to boost efficiency to commercially-useful levels. In addition to an intensive search for new materials, significant effort has been spent on ways to squeeze more performance out of existing materials, such as multijunction cells. This thesis investigates double junction tandem cells in the context of small molecule organic materials. . Two different organic electron donor materials, boron subphthalocyanine chloride (SubPc) and aluminium phthalocyanine chloride (ClAlPc) were used as donors in heterojunctions with C60 to create tandem cells for this thesis. These materials have been previously used for solar cells and the absorption spectra of the donor materials complement each other, making them good candidates for tandem cell architectures. The design of the recombination layer between the cells is considered first, with silver nanoparticles demonstrated to work well as recombination centres for charges from the front and back sub-cells, necessary to avoid a charge build-up at the interface. The growth conditions for the nanoparticles are optimised, with the tandem cells outperforming the single heterojunction architecture. Optical modelling is considered as a method to improve the understanding of thin film solar cells, where interference effects from the reflective aluminium electrode are important in determining the magnitude of absorption a cell can achieve. The use of such modelling is first demonstrated in hybrid solar cells based on a SubPc donor with a titanium oxide (TiOx) acceptor; this system is ideal for observing the effects of interference as only the SubPc layer has significant absorption. The modelling is then applied to tandem cells

  17. 加速溶剂萃取-固相萃取-液相色谱-电喷雾串联质谱法同时测定羊栖菜中六溴环十二烷异构体%Simultaneous determination of hexabromocyclododecane diastereoisomers in Sargassum fusiforme by accelerated solvent extraction-solid phase extraction-liquid chromatography-tandem mass spectrometry

    Institute of Scientific and Technical Information of China (English)

    韩超; 贾婉娉; 朱振瓯; 刘滨; 刘翠平; 沈燕

    2011-01-01

    采用同位素稀释-高效液相色谱-电喷雾串联四级杆质谱法同时测定羊栖菜中3种六溴环十二烷(HBCD)非对映异构体.羊栖菜样品磨碎、加入同位素内标13C-HBCD后以乙酸乙酯为提取溶剂,采用加速溶剂萃取法,使用Waters X Bridge(TM)C18反相柱分离;流动相为10mmoL的乙酸铵/乙腈(0.1%乙酸)/甲醇,在等度条件下分析,目标分析物在多反应监测(MRM)模式下以保留时间和离子对(母离子和两个碎片离子)信息比较进行定性分析,内标法定量.结果表明,在7min内即可完成α,β和γ-HBCD 3种同分异构体的分离,检测限(LOD)为0.3~1.0ng/g,定量限(LOQ)为1.0~4.0ng/g,添加水平为5、10和25ng/g时,3种被测物的加标回收率为92.7%~102.5%,相对标准偏差小于3.9%.本方法为评价羊栖菜样品质量提供了新的检测方法.%A method for the detection of α, β and γ-diastereoisomers of hexabrom ocyclododecanes (HBCDs) in Sargassum Fusiforme was developed using liquid chromatography-electrospray inonization mass spectrometry and isotope dilution. The samples were ground、added isotopic internal standard13C-HBCD and then extracted under the conditions of 10. 3 MPa and 80 ℃ by accelerated solvent extraction method with two static cycles using ethyl acetate as the extraction solvent. The extract was cleaned up by solid phase extraction cartridge. The analysis was performed on an Waters X BridgeTM C18 column(2.1 x 150 mm,3.5 μm) utilizing a isocratic elution profile and a mobile phase of water with 10 mmol/L ammonium acetate/acetonitrile with O. 1% acetic acid/ methanol.The analytes were detected using an electro-spray ionization tandem mass spectrometry with multiple reaction monitoring. Qualitative and quantitative analysis was based on the peak area of the parent ion and two fragment ions, and quantified by internal standard method. The results showed that the three HBCDs were separated within 7 min. The instrumental limits of

  18. Weather and air pollutants have an impact on patients with respiratory diseases and breathing difficulties in Munich, Germany

    Science.gov (United States)

    Wanka, E. R.; Bayerstadler, A.; Heumann, C.; Nowak, D.; Jörres, R. A.; Fischer, R.

    2014-03-01

    This study determined the influence of various meteorological variables and air pollutants on airway disorders in general, and asthma and/or chronic obstructive pulmonary disease in particular, in Munich, Bavaria, during 2006 and 2007. This was achieved through an evaluation of the daily frequency of calls to medical and emergency call centres, ambulatory medical care visits at general practitioners, and prescriptions of antibiotics for respiratory diseases. Meteorological parameters were extracted from data supplied by the European Centre for Medium Range Weather Forecast. Data on air pollutant levels were extracted from the air quality database of the European Environmental Agency for different measurement sites. In addition to descriptive analyses, a backward elimination procedure was performed to identify variables associated with medical outcome variables. Afterwards, generalised additive models (GAM) were used to verify whether the selected variables had a linear or nonlinear impact on the medical outcomes. The analyses demonstrated associations between environmental parameters and daily frequencies of different medical outcomes, such as visits at GPs and air pressure (-27 % per 10 hPa change) or ozone (-24 % per 10 μg/m3 change). The results of the GAM indicated that the effects of some covariates, such as carbon monoxide on consultations at GPs, or humidity on medical calls in general, were nonlinear, while the type of association varied between medical outcomes. These data suggest that the multiple, complex effect of environmental factors on medical outcomes should not be assumed homogeneous or linear a priori and that different settings might be associated with different types of associations.

  19. The Role of Vegetation in Mitigating Urban Land Surface Temperatures: A Case Study of Munich, Germany during the Warm Season

    Directory of Open Access Journals (Sweden)

    Sadroddin Alavipanah

    2015-04-01

    Full Text Available The Urban Heat Island (UHI is the phenomenon of altered increased temperatures in urban areas compared to their rural surroundings. UHIs grow and intensify under extreme hot periods, such as during heat waves, which can affect human health and also increase the demand for energy for cooling. This study applies remote sensing and land use/land cover (LULC data to assess the cooling effect of varying urban vegetation cover, especially during extreme warm periods, in the city of Munich, Germany. To compute the relationship between Land Surface Temperature (LST and Land Use Land Cover (LULC, MODIS eight-day interval LST data for the months of June, July and August from 2002 to 2012 and the Corine Land Cover (CLC database were used. Due to similarities in the behavior of surface temperature of different CLCs, some classes were reclassified and combined to form two major, rather simplified, homogenized classes: one of built-up area and one of urban vegetation. The homogenized map was merged with the MODIS eight-day interval LST data to compute the relationship between them. The results revealed that (i the cooling effect accrued from urban vegetation tended to be non-linear; and (ii a remarkable and stronger cooling effect in terms of LST was identified in regions where the proportion of vegetation cover was between seventy and almost eighty percent per square kilometer. The results also demonstrated that LST within urban vegetation was affected by the temperature of the surrounding built-up and that during the well-known European 2003 heat wave, suburb areas were cooler from the core of the urbanized region. This study concluded that the optimum green space for obtaining the lowest temperature is a non-linear trend. This could support urban planning strategies to facilitate appropriate applications to mitigate heat-stress in urban area.

  20. Physics and technical development of accelerators; Physique et technique des accelerateurs

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    About 90 registered participants delivered more than 40 scientific papers. A great part of these presentations were of general interest about running projects such as CIME accelerator at Ganil, IPHI (high intensity proton injector), ESRF (European source of synchrotron radiation), LHC (large hadron collider), ELYSE accelerator at Orsay, AIRIX, and VIVITRON tandem accelerator. Other presentations highlighted the latest technological developments of accelerator components: superconducting cavities, power klystrons, high current injectors..

  1. Accelerated Unification

    OpenAIRE

    Arkani-Hamed, Nima; Cohen, Andrew; Georgi, Howard

    2001-01-01

    We construct four dimensional gauge theories in which the successful supersymmetric unification of gauge couplings is preserved but accelerated by N-fold replication of the MSSM gauge and Higgs structure. This results in a low unification scale of $10^{13/N}$ TeV.

  2. MR-Tandem: parallel X!Tandem using Hadoop MapReduce on Amazon Web Services.

    Science.gov (United States)

    Pratt, Brian; Howbert, J Jeffry; Tasman, Natalie I; Nilsson, Erik J

    2012-01-01

    MR-Tandem adapts the popular X!Tandem peptide search engine to work with Hadoop MapReduce for reliable parallel execution of large searches. MR-Tandem runs on any Hadoop cluster but offers special support for Amazon Web Services for creating inexpensive on-demand Hadoop clusters, enabling search volumes that might not otherwise be feasible with the compute resources a researcher has at hand. MR-Tandem is designed to drop in wherever X!Tandem is already in use and requires no modification to existing X!Tandem parameter files, and only minimal modification to X!Tandem-based workflows. MR-Tandem is implemented as a lightly modified X!Tandem C++ executable and a Python script that drives Hadoop clusters including Amazon Web Services (AWS) Elastic Map Reduce (EMR), using the modified X!Tandem program as a Hadoop Streaming mapper and reducer. The modified X!Tandem C++ source code is Artistic licensed, supports pluggable scoring, and is available as part of the Sashimi project at http://sashimi.svn.sourceforge.net/viewvc/sashimi/trunk/trans_proteomic_pipeline/extern/xtandem/. The MR-Tandem Python script is Apache licensed and available as part of the Insilicos Cloud Army project at http://ica.svn.sourceforge.net/viewvc/ica/trunk/mr-tandem/. Full documentation and a windows installer that configures MR-Tandem, Python and all necessary packages are available at this same URL. brian.pratt@insilicos.com

  3. Nanocrystal assembly for tandem catalysis

    Science.gov (United States)

    Yang, Peidong; Somorjai, Gabor; Yamada, Yusuke; Tsung, Chia-Kuang; Huang, Wenyu

    2014-10-14

    The present invention provides a nanocrystal tandem catalyst comprising at least two metal-metal oxide interfaces for the catalysis of sequential reactions. One embodiment utilizes a nanocrystal bilayer structure formed by assembling sub-10 nm platinum and cerium oxide nanocube monolayers on a silica substrate. The two distinct metal-metal oxide interfaces, CeO.sub.2--Pt and Pt--SiO.sub.2, can be used to catalyze two distinct sequential reactions. The CeO.sub.2--Pt interface catalyzed methanol decomposition to produce CO and H.sub.2, which were then subsequently used for ethylene hydroformylation catalyzed by the nearby Pt--SiO.sub.2 interface. Consequently, propanal was selectively produced on this nanocrystal bilayer tandem catalyst.

  4. "Nanocrystal bilayer for tandem catalysis"

    Energy Technology Data Exchange (ETDEWEB)

    Yamada, Yusuke; Tsung, Chia Kuang; Huang, Wenyu; Huo, Ziyang; E.Habas, Susan E; Soejima, Tetsuro; Aliaga, Cesar E; Samorjai, Gabor A; Yang, Peidong

    2011-01-24

    Supported catalysts are widely used in industry and can be optimized by tuning the composition and interface of the metal nanoparticles and oxide supports. Rational design of metal-metal oxide interfaces in nanostructured catalysts is critical to achieve better reaction activities and selectivities. We introduce here a new class of nanocrystal tandem catalysts that have multiple metal-metal oxide interfaces for the catalysis of sequential reactions. We utilized a nanocrystal bilayer structure formed by assembling platinum and cerium oxide nanocube monolayers of less than 10 nm on a silica substrate. The two distinct metal-metal oxide interfaces, CeO2-Pt and Pt-SiO2, can be used to catalyse two distinct sequential reactions. The CeO2-Pt interface catalysed methanol decomposition to produce CO and H2, which were subsequently used for ethylene hydroformylation catalysed by the nearby Pt-SiO2 interface. Consequently, propanal was produced selectively from methanol and ethylene on the nanocrystal bilayer tandem catalyst. This new concept of nanocrystal tandem catalysis represents a powerful approach towards designing high-performance, multifunctional nanostructured catalysts

  5. Nanocrystal bilayer for tandem catalysis.

    Science.gov (United States)

    Yamada, Yusuke; Tsung, Chia-Kuang; Huang, Wenyu; Huo, Ziyang; Habas, Susan E; Soejima, Tetsuro; Aliaga, Cesar E; Somorjai, Gabor A; Yang, Peidong

    2011-05-01

    Supported catalysts are widely used in industry and can be optimized by tuning the composition and interface of the metal nanoparticles and oxide supports. Rational design of metal-metal oxide interfaces in nanostructured catalysts is critical to achieve better reaction activities and selectivities. We introduce here a new class of nanocrystal tandem catalysts that have multiple metal-metal oxide interfaces for the catalysis of sequential reactions. We utilized a nanocrystal bilayer structure formed by assembling platinum and cerium oxide nanocube monolayers of less than 10 nm on a silica substrate. The two distinct metal-metal oxide interfaces, CeO(2)-Pt and Pt-SiO(2), can be used to catalyse two distinct sequential reactions. The CeO(2)-Pt interface catalysed methanol decomposition to produce CO and H(2), which were subsequently used for ethylene hydroformylation catalysed by the nearby Pt-SiO(2) interface. Consequently, propanal was produced selectively from methanol and ethylene on the nanocrystal bilayer tandem catalyst. This new concept of nanocrystal tandem catalysis represents a powerful approach towards designing high-performance, multifunctional nanostructured catalysts.

  6. Cross-sectional, descriptive study of Chagas disease among citizens of Bolivian origin living in Munich, Germany

    Science.gov (United States)

    Navarro, Miriam; Berens-Riha, Nicole; Hohnerlein, Stefan; Seiringer, Peter; von Saldern, Charlotte; Garcia, Sarah; Blasco-Hernández, Teresa; Navaza, Bárbara; Shock, Jonathan; Bretzel, Gisela; Hoelscher, Michael; Löscher, Thomas; Albajar-Viñas, Pedro; Pritsch, Michael

    2017-01-01

    Purpose Chagas disease (CD) has become a global health issue mainly due to migration. Germany lacks surveillance data and is home to a large Latin American immigrant population. Recognising that Bolivia is the country with the highest CD prevalence in Latin America, this cross-sectional, descriptive pilot study investigated CD and associated factors among citizens of Bolivian origin living in Munich, Germany. Methods Participants completed a questionnaire in order to collect socioeconomic and health-related data. In addition, serology was performed. In case of positive serological tests, PCR diagnostic and clinical staging together with disease management was initiated. Qualitative research was conducted to identify personal and community barriers as well as strategies to increase CD awareness among the population at risk. Results Between June 2013 and June 2014, 43 people from Bolivia (or descendants) were enrolled. A total of 9.3% (4/43), of whom two women were of childbearing age, tested seropositive (ELISA and IFAT), and one also by PCR. For 2/4 positive participants, clinical evaluation was performed and the indeterminate form of CD was diagnosed. Knowledge about CD symptoms and ways of transmission were completely absent among 55.8% (24/43, 2/4 with CD) and 30.2% (13/43, 1/4 with CD) of participants, respectively. A total of 27.9% (12/43, 0/4 with CD) of participants had donated blood prior to the study, whereas 62.8% (27/43, 3/4 with CD) were motivated to donate blood in the future. The qualitative research identified lack of knowledge as well as stigma and fears related to CD. Conclusions Despite the small number of participants, the prevalence of CD as well as the potential risk of non-vectorial transmission was alarming. Campaigns adapted for Latin American migrants as well as control strategies should be developed and put in place in order to prevent non-vectorial transmission and actively detect cases of CD in Germany. PMID:28093440

  7. Japanese version of the Munich Parasomnia Screening: translation and linguistic validation of a screening instrument for parasomnias and nocturnal behaviors

    Directory of Open Access Journals (Sweden)

    Komada Y

    2015-11-01

    Full Text Available Yoko Komada,1 Raoul Breugelmans,2 Stephany Fulda,3 Sae Nakano,4 Aya Watanabe,4,5 Chieri Noda,4,6 Shingo Nishida,1 Yuichi Inoue1 1Department of Somnology, 2Department of Medical Education, Tokyo Medical University, Tokyo, Japan; 3Sleep and Epilepsy Center, Neurocenter of Southern Switzerland, Civic Hospital (EOC of Lugano, Lugano, Switzerland; 4Department of International Medical Communications, Tokyo Medical University, Tokyo, 5Language Center, University of Fukui, Fukui, Japan; 6Department of Applied Linguistics and Communication, Birkbeck, University of London, London, UK Objective: There is no broad screening instrument that can comprehensively assess parasomnias and sleep-related movement disorders listed in the International Classification of Sleep Disorders. The aim of this study was to develop the Japanese version of the Munich Parasomnia Screening (MUPS, a screening instrument for parasomnias and nocturnal behaviors, which was developed and validated at the Max Planck Institute of Psychiatry. Methods: A multi-step translation methodology consisting of forward translation, back translation, expert review, and cognitive debriefing interviews was performed between June and November 2011. Results: The English version of the MUPS was translated into Japanese, and the original author performed an expert review on the basis of a detailed report on the forward and back translation steps. The cognitive debriefing was carried out in five patients with parasomnia. The mean time to fill out the questionnaire was 8 minutes (ranging from 2 to 17 minutes. The authors reviewed and discussed the results of the cognitive debriefing interviews and modified the Japanese version. The final Japanese version was confirmed to be conceptually equivalent to the original English version. Conclusion: The Japanese version of the MUPS is an easy-to-use self-rating instrument for parasomnia and nocturnal behavior screening, consistent with the original version. The

  8. Particle Accelerators in China

    Science.gov (United States)

    Zhang, Chuang; Fang, Shouxian

    As the special machines that can accelerate charged particle beams to high energy by using electromagnetic fields, particle accelerators have been widely applied in scientific research and various areas of society. The development of particle accelerators in China started in the early 1950s. After a brief review of the history of accelerators, this article describes in the following sections: particle colliders, heavy-ion accelerators, high-intensity proton accelerators, accelerator-based light sources, pulsed power accelerators, small scale accelerators, accelerators for applications, accelerator technology development and advanced accelerator concepts. The prospects of particle accelerators in China are also presented.

  9. [Proceedings: The clinical effects of human growth hormone. Report on an international symposium of the German Kabi Corp. on February 15, 1975 in Munich].

    Science.gov (United States)

    Butenandt, O

    1975-09-11

    Report of an International Symposion (Febr. 15, 1975, Munich). Human growth hormone (HGH) acts on proliferation of cartilage, the basal process of growth, by the way of somatomedine and changes in protein metabolism. Growth can be enhanced in hypopituitary dwardism and with higher dosage in other forms of failure to thrive. HGH also seems to have a beneficial effect in patients with muscular dystrophy as shown in a preliminary report but not in thrombocytopenia. First observations on patients with osteogenesis imperfecta and on patients with non healing fractures of the long bones (pseudarthroses) have shown significant improvement. Of importance are the reports on stopping severe gastric hemorrhage in patients with stress ulcera.

  10. The impact of the social environment on children's mental health in a prosperous city: an analysis with data from the city of Munich

    Directory of Open Access Journals (Sweden)

    Spies Gabriele

    2010-04-01

    Full Text Available Abstract Background Children with a low socioeconomic position are more affected by mental difficulties as compared to children with a higher socioeconomic position. This paper explores whether this socioeconomic pattern persists in the prosperous German city of Munich which features high quality of life and coverage of children mental health specialists that lies well above the national average and is among the highest in Europe. Methods 1,265 parents of preschool children participated in a cross-sectional health survey. They were given a self-administered questionnaire (including socioeconomic variables and the 'Strengths and Difficulties Questionnaire (SDQ', a well-established method to identify mental difficulties among children and adolescents. Prevalence estimates for the 'SDQ-Total Difficulties Score' were calculated, with a special focus on differences by parental (resp. household socioeconomic position. The association between parental education, household income, single parenthood, nationality, and parental working status on one hand, and their children's mental health on the other, was explored using multivariable logistic regression models. The coverage of mental health specialists per 100,000 children aged 14 or younger in the city of Munich was also calculated. Results In Munich, the distribution of mental health difficulties among children follows the same socioeconomic pattern as described previously at the national level, but the overall prevalence is about 30% lower. Comparing different indicators of socioeconomic position, low parental education and household income are the strongest independent variables associated with mental difficulties among children (OR = 2.7; CI = 1.6 - 4.4 and OR = 2.8; CI = 1.4 - 5.6, respectively. Conclusions Socioeconomic differences in the prevalence of childhood mental difficulties are very stable. Even in a city such as Munich, which is characterized by high quality of life, high availability of

  11. Development of overt proteinuria in the Munich Wistar Frömter rat is suppressed by replacement of chromosome 6 in a consomic rat strain

    DEFF Research Database (Denmark)

    Schulz, Angela; Weiss, Judith; Schlesener, Maria

    2007-01-01

    In a cross between the Munich Wistar Frömter (MWF) rat and spontaneously hypertensive rats (SHR), a major quantitative trait locus (QTL) was identified on rat chromosome 6 (RNO6) that demonstrated the strongest linkage to albuminuria among several QTL identified. The QTL represented the only locu...... in MWF is determined by a complex interplay of several QTL, our data demonstrate that genetic exchange of one locus on RNO6 leads to marked suppression of early-onset albuminuria and renal damage in MWF. Udgivelsesdato: 2007-Jan...

  12. Advertisement for solar energy. Munich fairground buildings with the world`s biggest PV system; Werbung fuer Solarenergie. Messe Muenchen realisiert groesste Photovoltaikanlage der Welt

    Energy Technology Data Exchange (ETDEWEB)

    Schmid, W.

    1998-03-01

    On 19 November 1997, the 1 MW solar system of the new Munich fairground was commissioned on a bright and sunny day. According to the Bayernwerk AG, it is the world`s biggest roof-mounted photovoltaic system. It was constructed in only 10 months at a cost of DM 15 million. (orig.) [Deutsch] Bei strahlendem Sonnenschein wurde am 19. November 1997 auf dem Gelaende der Neuen Messe Muenchen die Ein-Megawatt-Solaranlage in Betrieb genommen. Nach Aussagen der Bayernwerk AG ist sie `die groesste Photovoltaik-Dachanlage der Welt`. Sie wurde in nur zehn Monaten Bauzeit auf den Hallendaechern installiert. Die Kosten beliefen sich auf 15 Mio DM. (orig.)

  13. Reanálisis del diagnóstico de alcoholismo en Perú: el test de alcoholismo Munich (malt

    Directory of Open Access Journals (Sweden)

    Klaus-Dieter Gorené

    1992-12-01

    Full Text Available El Test de Alcoholismo Munich (MALT fue traducido al español y aplicado a una muestra constituida por 145 probandos peruanos, de los cuales 94 eran alcohólicos. El MALT consta de dos partes: la primera está conformada por siete preguntas que son contestadas por el médico y la segunda sección está formada por 24 preguntas y son contestadas por el paciente. Tanto el coeficiente de validación para toda la prueba (r=0.87 como el coeficiente de confiabilidad de la parte autoadministrable (r=0.93 fueron elevados.

  14. MUON ACCELERATION

    Energy Technology Data Exchange (ETDEWEB)

    BERG,S.J.

    2003-11-18

    One of the major motivations driving recent interest in FFAGs is their use for the cost-effective acceleration of muons. This paper summarizes the progress in this area that was achieved leading up to and at the FFAG workshop at KEK from July 7-12, 2003. Much of the relevant background and references are also given here, to give a context to the progress we have made.

  15. Laser acceleration

    Science.gov (United States)

    Tajima, T.; Nakajima, K.; Mourou, G.

    2017-02-01

    The fundamental idea of Laser Wakefield Acceleration (LWFA) is reviewed. An ultrafast intense laser pulse drives coherent wakefield with a relativistic amplitude robustly supported by the plasma. While the large amplitude of wakefields involves collective resonant oscillations of the eigenmode of the entire plasma electrons, the wake phase velocity ˜ c and ultrafastness of the laser pulse introduce the wake stability and rigidity. A large number of worldwide experiments show a rapid progress of this concept realization toward both the high-energy accelerator prospect and broad applications. The strong interest in this has been spurring and stimulating novel laser technologies, including the Chirped Pulse Amplification, the Thin Film Compression, the Coherent Amplification Network, and the Relativistic Mirror Compression. These in turn have created a conglomerate of novel science and technology with LWFA to form a new genre of high field science with many parameters of merit in this field increasing exponentially lately. This science has triggered a number of worldwide research centers and initiatives. Associated physics of ion acceleration, X-ray generation, and astrophysical processes of ultrahigh energy cosmic rays are reviewed. Applications such as X-ray free electron laser, cancer therapy, and radioisotope production etc. are considered. A new avenue of LWFA using nanomaterials is also emerging.

  16. Short Tandem Repeat DNA Internet Database

    Science.gov (United States)

    SRD 130 Short Tandem Repeat DNA Internet Database (Web, free access)   Short Tandem Repeat DNA Internet Database is intended to benefit research and application of short tandem repeat DNA markers for human identity testing. Facts and sequence information on each STR system, population data, commonly used multiplex STR systems, PCR primers and conditions, and a review of various technologies for analysis of STR alleles have been included.

  17. Accelerators and the Accelerator Community

    Energy Technology Data Exchange (ETDEWEB)

    Malamud, Ernest; Sessler, Andrew

    2008-06-01

    In this paper, standing back--looking from afar--and adopting a historical perspective, the field of accelerator science is examined. How it grew, what are the forces that made it what it is, where it is now, and what it is likely to be in the future are the subjects explored. Clearly, a great deal of personal opinion is invoked in this process.

  18. SETUP AND PERFORMANCE OF THE RHIC INJECTOR ACCELERATORS FOR THE 2005 RUN WITH COPPER IONS.

    Energy Technology Data Exchange (ETDEWEB)

    AHRENS, L.; ALESSI, J.; GARDNER, C.J.

    2005-05-16

    Copper ions for the 2005 run [1] of the Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Laboratory (BNL) are accelerated in the Tandem, Booster and AGS prior to injection into RHIC. The setup and performance of these accelerators with copper are reviewed in this paper.

  19. Burden of relatives and predictors of burden. Baseline results from the Munich 5-year-follow-up study on relatives of first hospitalized patients with schizophrenia or depression.

    Science.gov (United States)

    Möller-Leimkühler, Anne Maria

    2005-08-01

    In the present study, part of the Munich 5-year follow-up study on key relatives of first-hospitalized schizophrenic and depressive patients, baseline results with respect to relatives' burden and predictors of burden are presented. Basing on a transactional stress model the following hypothesis was tested: the impact of the patients' illness on their relatives' stress outcome is moderated by the psychosocial resources of the relatives. Stress outcome was measured in terms of objective and subjective burden, well-being, self-rated symptoms and global satisfaction with life. Potential moderating variables included age and gender, generalized stress response and illness-related coping strategies, beliefs of control,perceived social support,personality factors, expressed emotion and life stressors. A total of 83 relatives, whose ill family members had been hospitalized in the Department of Psychiatry of the Ludwig-Maximilians-University of Munich for the first time, participated in the study. Findings did not entirely support the hypothesis. On the one hand, relatives' stress outcome was independent of the objective stressors (severity of the illness, kind of symptoms, level of psychosocial functioning at admission). On the other hand, burden was significantly associated with several psychosocial resources and dispositions of the relatives. Multivariate linear regression analyses indicated that expressed emotion, emotion-focused coping strategies and generalized negative stress response are the most relevant predictors of burden. It is argued that a multidimensional approach in burden assessment is necessary and has relevant implications for improving family intervention strategies.

  20. accelerating cavity

    CERN Multimedia

    On the inside of the cavity there is a layer of niobium. Operating at 4.2 degrees above absolute zero, the niobium is superconducting and carries an accelerating field of 6 million volts per metre with negligible losses. Each cavity has a surface of 6 m2. The niobium layer is only 1.2 microns thick, ten times thinner than a hair. Such a large area had never been coated to such a high accuracy. A speck of dust could ruin the performance of the whole cavity so the work had to be done in an extremely clean environment.

  1. Impact accelerations

    Science.gov (United States)

    Vongierke, H. E.; Brinkley, J. W.

    1975-01-01

    The degree to which impact acceleration is an important factor in space flight environments depends primarily upon the technology of capsule landing deceleration and the weight permissible for the associated hardware: parachutes or deceleration rockets, inflatable air bags, or other impact attenuation systems. The problem most specific to space medicine is the potential change of impact tolerance due to reduced bone mass and muscle strength caused by prolonged weightlessness and physical inactivity. Impact hazards, tolerance limits, and human impact tolerance related to space missions are described.

  2. Tandem mirror technology demonstration facility

    Energy Technology Data Exchange (ETDEWEB)

    1983-10-01

    This report describes a facility for generating engineering data on the nuclear technologies needed to build an engineering test reactor (ETR). The facility, based on a tandem mirror operating in the Kelley mode, could be used to produce a high neutron flux (1.4 MW/M/sup 2/) on an 8-m/sup 2/ test area for testing fusion blankets. Runs of more than 100 h, with an average availability of 30%, would produce a fluence of 5 mW/yr/m/sup 2/ and give the necessary experience for successful operation of an ETR.

  3. Device operation of organic tandem solar cells

    NARCIS (Netherlands)

    Hadipour, A.; de Boer, B.; Blom, P. W. M.

    2008-01-01

    A generalized methodology is developed to obtain the current-voltage characteristic of polymer tandem solar cells by knowing the electrical performance of both sub cells. We demonstrate that the electrical characteristics of polymer tandem solar cells are correctly predicted for both the series and

  4. Packet models revisited: tandem and priority systems

    NARCIS (Netherlands)

    Mandjes, M.R.H.

    2004-01-01

    We examine two extensions of traditional single-node packet-scale queueing models: tandem networks and (strict) priority systems. Two generic input processes are considered: periodic and Poisson arrivals. For the two-node tandem, an exact expression is derived for the joint distribution of the total

  5. Packet models revisited: tandem and priority systems

    NARCIS (Netherlands)

    M.R.H. Mandjes

    2004-01-01

    Abstract : We examine two extensions of traditional single-node packet-scale queueing models: tandem networks and (strict) priority systems. Two generic input processes are considered: periodic and Poisson arrivals. For the two-node tandem, an exact expression is derived for the joint distribution o

  6. Device operation of organic tandem solar cells

    NARCIS (Netherlands)

    Hadipour, A.; de Boer, B.; Blom, P. W. M.

    2008-01-01

    A generalized methodology is developed to obtain the current-voltage characteristic of polymer tandem solar cells by knowing the electrical performance of both sub cells. We demonstrate that the electrical characteristics of polymer tandem solar cells are correctly predicted for both the series and

  7. Detecting long tandem duplications in genomic sequences

    Directory of Open Access Journals (Sweden)

    Audemard Eric

    2012-05-01

    Full Text Available Abstract Background Detecting duplication segments within completely sequenced genomes provides valuable information to address genome evolution and in particular the important question of the emergence of novel functions. The usual approach to gene duplication detection, based on all-pairs protein gene comparisons, provides only a restricted view of duplication. Results In this paper, we introduce ReD Tandem, a software using a flow based chaining algorithm targeted at detecting tandem duplication arrays of moderate to longer length regions, with possibly locally weak similarities, directly at the DNA level. On the A. thaliana genome, using a reference set of tandem duplicated genes built using TAIR,a we show that ReD Tandem is able to predict a large fraction of recently duplicated genes (dS  Conclusions ReD Tandem allows to identify large tandem duplications without any annotation, leading to agnostic identification of tandem duplications. This approach nicely complements the usual protein gene based which ignores duplications involving non coding regions. It is however inherently restricted to relatively recent duplications. By recovering otherwise ignored events, ReD Tandem gives a more comprehensive view of existing evolutionary processes and may also allow to improve existing annotations.

  8. Heavy-ion acceleration with a superconducting linac

    Energy Technology Data Exchange (ETDEWEB)

    Bollinger, L.M.

    1988-01-01

    This year, 1988, is the tenth anniversary of the first use of RF superconductivity to accelerate heavy ions. In June 1978, the first two superconducting resonators of the Argonne Tandem-Linac Accelerator System (ATLAS) were used to boost the energy of a /sup 19/F beam from the tandem, and by September 1978 a 5-resonator linac provided an /sup 16/O beam for a nuclear-physics experiment. Since then, the superconducting linac has grown steadily in size and capability until now there are 42 accelerating structures and 4 bunchers. Throughout this period, the system was used routinely for physics research, and by now the total time with beam on target is 35,000 hours. Lessons learned from this long running experience and some key technical developments that made it possible are reviewed in this paper. 19 refs., 3 figs., 2 tabs.

  9. Tandem Catalysis Utilizing Olefin Metathesis Reactions.

    Science.gov (United States)

    Zieliński, Grzegorz K; Grela, Karol

    2016-07-01

    Since olefin metathesis transformation has become a favored synthetic tool in organic synthesis, more and more distinct non-metathetical reactions of alkylidene ruthenium complexes have been developed. Depending on the conditions applied, the same olefin metathesis catalysts can efficiently promote isomerization reactions, hydrogenation of C=C double bonds, oxidation reactions, and many others. Importantly, these transformations can be carried out in tandem with olefin metathesis reactions. Through addition of one portion of a catalyst, a tandem process provides structurally advanced products from relatively simple substrates without the need for isolation of the intermediates. These aspects not only make tandem catalysis very attractive from a practical point of view, but also open new avenues in (retro)synthetic planning. However, in the literature, the term "tandem process" is sometimes used improperly to describe other types of multi-reaction sequences. In this Concept, a number of examples of tandem catalysis involving olefin metathesis are discussed with an emphasis on their synthetic value.

  10. The 17{sup th} European photovoltaic solar energy conference and exhibition in Munich from a Swiss point of view; Die 17. europaeische Photovoltaikkonferenz in Muenchen aus Schweizer Sicht

    Energy Technology Data Exchange (ETDEWEB)

    Nowak, S.

    2002-07-01

    This report for the Swiss Federal Office of Energy (SFOE) summarises the photovoltaics (PV) conference and exhibition held in Munich in October 2001 from the Swiss point of view. The contributions made by representatives of Swiss institutions and companies are presented including papers on the progress being made in third generation crystalline and multi-crystalline silicon technology, amorphous and micro-crystalline silicon solar cells, thin film solar cells based on compound semiconductors and thermo-photovoltaics. Further papers deal with PV modules on the market, building-integrated solar power systems and new developments in PV systems technology. The exhibition that accompanied the conference, including the 12 Swiss exhibitors who were present, is reviewed as are international market developments. Contributions concerning the application of photovoltaics in developing countries are also reviewed.

  11. Optimization of a partially non-magnetic primary radiation shielding for the triple-axis spectrometer PANDA at the Munich high-flux reactor FRM-II

    CERN Document Server

    Pyka, N M; Rogov, A

    2002-01-01

    Monte Carlo simulations have been used to optimize the monochromator shielding of the polarized cold-neutron triple-axis spectrometer PANDA at the Munich high-flux reactor FRM-II. By using the Monte Carlo program MCNP-4B, the density of the total spectrum of incoming neutrons and gamma radiation from the beam tube SR-2 has been determined during the three-dimensional diffusion process in different types of heavy concrete and other absorbing material. Special attention has been paid to build a compact and highly efficient shielding, partially non-magnetic, with a total biological radiation dose of less than 10 mu Sv/h at its outsides. Especially considered was the construction of an albedo reducer, which serves to reduce the background in the experiment outside the shielding. (orig.)

  12. Mathematical Performance of Students with Special Needs in Secondary Schools. An Exploratory Study of the Fifth to the Ninth Grade in Munich Special Schools

    Directory of Open Access Journals (Sweden)

    Markus Gebhardt

    2013-06-01

    Full Text Available The major goal of the Test was to determine mathematical skills of students with special educational needs (SEN from fifth to ninth grade. Based on a sample of 124 students with special educational needs (SEN of three special schools in Munich it is shown, that the skills are within a very heterogeneous range. As a general rule basic mathematical skills, such as quantity-number competencies and knowledge of mathematical conventions and rules, were not applied properly by most of the students. Although in average the math skills improve in higher grades, school performance by grade level and age were no significant in the regression models. There is a significant connection between "necessary support" and the "state after the regular curriculum" mathematics performance.

  13. Measurement of neutron flux and beam divergence at the cold neutron guide system of the new Munich research reactor FRM-II

    Science.gov (United States)

    Zeitelhack, K.; Schanzer, C.; Kastenmüller, A.; Röhrmoser, A.; Daniel, C.; Franke, J.; Gutsmiedl, E.; Kudryashov, V.; Maier, D.; Päthe, D.; Petry, W.; Schöffel, T.; Schreckenbach, K.; Urban, A.; Wildgruber, U.

    2006-05-01

    A sophisticated neutron guide system has been installed at the new Munich neutron source FRM-II to transport neutrons from the D 2 cold neutron source to several instruments, which are situated in a separate neutron guide hall. The guide system takes advantage of supermirror coatings and includes a worldwide unique "twisted" guide for a desired phase space transformation of the neutron beam. During the initial reactor commissioning in summer 2004, the integral and differential neutron flux as well as the distribution of beam divergence at the exit of two representative and the twisted neutron guide were measured using time-of-flight spectroscopy and gold-foil activation. The experimental results can be compared to extensive simulation calculations based on MCNP and McStas. The investigated guides fulfill the expectations of providing high neutron fluxes and reveal good quality with respect to the reflective coatings and the installation precision.

  14. Measurement of neutron flux and beam divergence at the cold neutron guide system of the new Munich research reactor FRM-II

    Energy Technology Data Exchange (ETDEWEB)

    Zeitelhack, K. [ZWE FRM-II, TU Muenchen, D-85747 Garching (Germany)]. E-mail: karl.zeitelhack@frm2.tum.de; Schanzer, C. [Physik-Department E21, TU Muenchen, D-85747 Garching (Germany); Kastenmueller, A. [ZWE FRM-II, TU Muenchen, D-85747 Garching (Germany); Roehrmoser, A. [ZWE FRM-II, TU Muenchen, D-85747 Garching (Germany); Daniel, C. [Physik-Department E22, TU Muenchen, D-85747 Garching (Germany); Franke, J. [Max-Planck-Institut fuer Metallforschung, D-70569 Stuttgart (Germany); Gutsmiedl, E. [ZWE FRM-II, TU Muenchen, D-85747 Garching (Germany); Kudryashov, V. [GKSS Forschungszentrum GmbH, D-21502 Geesthacht (Germany); Maier, D. [ZWE FRM-II, TU Muenchen, D-85747 Garching (Germany); Paethe, D. [ZWE FRM-II, TU Muenchen, D-85747 Garching (Germany); Petry, W. [ZWE FRM-II, TU Muenchen, D-85747 Garching (Germany); Schoeffel, T. [ZWE FRM-II, TU Muenchen, D-85747 Garching (Germany); Schreckenbach, K. [ZWE FRM-II, TU Muenchen, D-85747 Garching (Germany); Urban, A. [ZWE FRM-II, TU Muenchen, D-85747 Garching (Germany); Wildgruber, U. [Max-Planck-Institut fuer Metallforschung, D-70569 Stuttgart (Germany)

    2006-05-10

    A sophisticated neutron guide system has been installed at the new Munich neutron source FRM-II to transport neutrons from the D{sub 2} cold neutron source to several instruments, which are situated in a separate neutron guide hall. The guide system takes advantage of supermirror coatings and includes a worldwide unique 'twisted' guide for a desired phase space transformation of the neutron beam. During the initial reactor commissioning in summer 2004, the integral and differential neutron flux as well as the distribution of beam divergence at the exit of two representative and the twisted neutron guide were measured using time-of-flight spectroscopy and gold-foil activation. The experimental results can be compared to extensive simulation calculations based on MCNP and McStas. The investigated guides fulfill the expectations of providing high neutron fluxes and reveal good quality with respect to the reflective coatings and the installation precision.

  15. Psychiatric research and science policy in Germany: the history of the Deutsche Forschungsanstalt fur Psychiatrie (German Institute for Psychiatric Research) in Munich from 1917 to 1945).

    Science.gov (United States)

    Weber, M M

    2000-09-01

    The Deutsche Forschungsanstalt fur Psychiatrie (DFA) in Munich, one of the most important research institutes in the field of theoretical and clinical psychiatry, was founded in 1917 by Emil Kraepelin. Its financial existence between the world wars was assured by generous donations from the Jewish American scholar and philanthropist James Loeb. The scientific work done by Walther Spielmeyer (neuropathology), Felix Plaut (serology), Kurt Schneider (clinical psychiatry) and Ernst Rudin (psychiatric genetics) earned the DFA a reputation as an international center for psychiatry and neurology. During the 'Third Reich' Ernst Rudin cooperated with the National Socialist health system. His genetic concepts provided support for eugenic programmes such as forced sterilization of individuals with psychoses. These complex interactions underscore the importance of the DFA in understanding the recent history of medicine in Germany.

  16. Tandem Mirror Reactor Systems Code (Version I)

    Energy Technology Data Exchange (ETDEWEB)

    Reid, R.L.; Finn, P.A.; Gohar, M.Y.; Barrett, R.J.; Gorker, G.E.; Spampinaton, P.T.; Bulmer, R.H.; Dorn, D.W.; Perkins, L.J.; Ghose, S.

    1985-09-01

    A computer code was developed to model a Tandem Mirror Reactor. Ths is the first Tandem Mirror Reactor model to couple, in detail, the highly linked physics, magnetics, and neutronic analysis into a single code. This report describes the code architecture, provides a summary description of the modules comprising the code, and includes an example execution of the Tandem Mirror Reactor Systems Code. Results from this code for two sensitivity studies are also included. These studies are: (1) to determine the impact of center cell plasma radius, length, and ion temperature on reactor cost and performance at constant fusion power; and (2) to determine the impact of reactor power level on cost.

  17. Towards swift ion bunch acceleration by high-power laser pulses at the Centre for Advanced Laser Applications (CALA)

    Science.gov (United States)

    Lindner, F. H.; Haffa, D.; Bin, J. H.; Englbrecht, F.; Gao, Y.; Gebhard, J.; Hartmann, J.; Hilz, P.; Kreuzer, C.; Lehrack, S.; Ostermayr, T. M.; Rösch, T. F.; Speicher, M.; Würl, M.; Parodi, K.; Schreiber, J.; Thirolf, P. G.

    2017-07-01

    Laser-driven acceleration of ions has inspired novel applications, that can benefit from ion bunch properties different from conventionally (non-laser based) accelerated particle beams. Those differences range from extremely short bunch durations, broad energy spectra, large divergence angles and small source sizes to ultra-high ion bunch densities. So far, the main focus of research has been concentrating on the physics of the interaction of intense laser pulses with plasmas and the related mechanisms of ion acceleration. Now, the new Centre for Advanced Laser Applications (CALA) near Munich aims at pushing these ion bunches towards applications, including radiation therapy of tumors and the development of heavy ion bunches with solid-state-like density. These are needed for novel reaction mechanisms ('fission-fusion') to study the origin of heavy elements in the universe and to prepare for related studies at the upcoming EU-funded high-power laser facility ELI - Nuclear Physics in Bucharest.

  18. Inverted 3J Tandem Thermophotovoltaic Modules Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Spire Semiconductor proposes to make an InGaAs-based three-junction (3J) tandem thermophotovoltaic (TPV) cell to utilize more of the blackbody spectrum (from a GPHS)...

  19. Large deviations for tandem queueing systems

    Directory of Open Access Journals (Sweden)

    Roland L. Dobrushin

    1994-01-01

    Full Text Available The crude asymptotics of the large delay probability in a tandem queueing system is considered. The main result states that one of the two channels in the tandem system defines the crude asymptotics. The constant that determines the crude asymptotics is given. The results obtained are based on the large deviation principle for random processes with independent increments on an infinite interval recently established by the authors.

  20. Subattomole sensitivity in biological accelerator mass spectrometry.

    Science.gov (United States)

    Salehpour, Mehran; Possnert, Göran; Bryhni, Helge

    2008-05-15

    The Uppsala University 5 MV Pelletron tandem accelerator has been used to study (14)C-labeled biological samples utilizing accelerator mass spectrometry (AMS) technology. We have adapted a sample preparation method for small biological samples down to a few tens of micrograms of carbon, involving among others, miniaturizing of the graphitization reactor. Standard AMS requires about 1 mg of carbon with a limit of quantitation of about 10 amol. Results are presented for a range of small sample sizes with concentrations down to below 1 pM of a pharmaceutical substance in human blood. It is shown that (14)C-labeled molecular markers can be routinely measured from the femtomole range down to a few hundred zeptomole (10 (-21) mol), without the use of any additional separation methods.

  1. Ion acceleration from relativistic laser nano-target

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Daniel

    2012-01-06

    Laser-ion acceleration has been of particular interest over the last decade for fundamental as well as applied sciences. Remarkable progress has been made in realizing laser-driven accelerators that are cheap and very compact compared with conventional rf-accelerators. Proton and ion beams have been produced with particle energies of up to 50 MeV and several MeV/u, respectively, with outstanding properties in terms of transverse emittance and current. These beams typically exhibit an exponentially decaying energy distribution, but almost all advanced applications, such as oncology, proton imaging or fast ignition, require quasimonoenergetic beams with a low energy spread. The majority of the experiments investigated ion acceleration in the target normal sheath acceleration (TNSA) regime with comparably thick targets in the {mu}m range. In this thesis ion acceleration is investigated from nm-scaled targets, which are partially produced at the University of Munich with thickness as low as 3 nm. Experiments have been carried out at LANL's Trident high-power and high-contrast laser (80 J, 500 fs, {lambda}=1054 nm), where ion acceleration with these nano-targets occurs during the relativistic transparency of the target, in the so-called Breakout afterburner (BOA) regime. With a novel high resolution and high dispersion Thomson parabola and ion wide angle spectrometer, thickness dependencies of the ions angular distribution, particle number, average and maximum energy have been measured. Carbon C{sup 6+} energies reached 650 MeV and 1 GeV for unheated and heated targets, respectively, and proton energies peaked at 75 MeV and 120 MeV for diamond and CH{sub 2} targets. Experimental data is presented, where the conversion efficiency into carbon C{sup 6+} (protons) is investigated and found to have an up to 10fold (5fold) increase over the TNSA regime. With circularly polarized laser light, quasi-monoenergetic carbon ions have been generated from the same nm-scaled foil

  2. Felsenkeller shallow-underground accelerator laboratory for nuclear astrophysics

    Directory of Open Access Journals (Sweden)

    Bemmerer D.

    2015-01-01

    Based on this finding, a used 5 MV pelletron tandem with 250 μA upcharge current and external sputter ion source has been obtained and transported to Dresden. Work on an additional radio-frequency ion source on the high voltage terminal is underway. The project is now fully funded. The installation of the accelerator in the Felsenkeller is expected for the near future. The status of the project and the planned access possibilities for external users will be reported.

  3. Piezoelectric particle accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Kemp, Mark A.; Jongewaard, Erik N.; Haase, Andrew A.; Franzi, Matthew

    2017-08-29

    A particle accelerator is provided that includes a piezoelectric accelerator element, where the piezoelectric accelerator element includes a hollow cylindrical shape, and an input transducer, where the input transducer is disposed to provide an input signal to the piezoelectric accelerator element, where the input signal induces a mechanical excitation of the piezoelectric accelerator element, where the mechanical excitation is capable of generating a piezoelectric electric field proximal to an axis of the cylindrical shape, where the piezoelectric accelerator is configured to accelerate a charged particle longitudinally along the axis of the cylindrical shape according to the piezoelectric electric field.

  4. Acceleration without Horizons

    CERN Document Server

    Doria, Alaric

    2015-01-01

    We derive the metric of an accelerating observer moving with non-constant proper acceleration in flat spacetime. With the exception of a limiting case representing a Rindler observer, there are no horizons. In our solution, observers can accelerate to any desired terminal speed $v_{\\infty} < c$. The motion of the accelerating observer is completely determined by the distance of closest approach and terminal velocity or, equivalently, by an acceleration parameter and terminal velocity.

  5. Tandemly Arrayed Genes in Vertebrate Genomes

    Directory of Open Access Journals (Sweden)

    Deng Pan

    2008-01-01

    Full Text Available Tandemly arrayed genes (TAGs are duplicated genes that are linked as neighbors on a chromosome, many of which have important physiological and biochemical functions. Here we performed a survey of these genes in 11 available vertebrate genomes. TAGs account for an average of about 14% of all genes in these vertebrate genomes, and about 25% of all duplications. The majority of TAGs (72–94% have parallel transcription orientation (i.e., they are encoded on the same strand in contrast to the genome, which has about 50% of its genes in parallel transcription orientation. The majority of tandem arrays have only two members. In all species, the proportion of genes that belong to TAGs tends to be higher in large gene families than in small ones; together with our recent finding that tandem duplication played a more important role than retroposition in large families, this fact suggests that among all types of duplication mechanisms, tandem duplication is the predominant mechanism of duplication, especially in large families. Finally, several species have a higher proportion of large tandem arrays that are species-specific than random expectation.

  6. The combinatorics of tandem duplication trees.

    Science.gov (United States)

    Gascuel, Olivier; Hendy, Michael D; Jean-Marie, Alain; McLachlan, Robert

    2003-02-01

    We developed a recurrence relation that counts the number of tandem duplication trees (either rooted or unrooted) that are consistent with a set of n tandemly repeated sequences generated under the standard unequal recombination (or crossover) model of tandem duplications. The number of rooted duplication trees is exactly twice the number of unrooted trees, which means that on average only two positions for a root on a duplication tree are possible. Using the recurrence, we tabulated these numbers for small values of n. We also developed an asymptotic formula that for large n provides estimates for these numbers. These numbers give a priori probabilities for phylogenies of the repeated sequences to be duplication trees. This work extends earlier studies where exhaustive counts of the numbers for small n were obtained. One application showed the significance of finding that most maximum-parsimony trees constructed from repeat sequences from human immunoglobins and T-cell receptors were tandem duplication trees. Those findings provided strong support to the proposed mechanisms of tandem gene duplication. The recurrence relation also suggests efficient algorithms to recognize duplication trees and to generate random duplication trees for simulation. We present a linear-time recognition algorithm.

  7. Accelerating flight: Edge with arbitrary acceleration

    CSIR Research Space (South Africa)

    Gledhill, Irvy MA

    2011-11-01

    Full Text Available ? temporal scales ? Euler ? convection ? Reynolds ? translational viscous ? Ekman ? rotational viscous ? Translational acceleration ? related to g ? Rotational accleration ? Rossby ? Coriolis ? Centrifugal ? Gravitational ? CSIR 2009...

  8. Development of the Accelerator Mass Spectrometry technology at the Comenius University in Bratislava

    Energy Technology Data Exchange (ETDEWEB)

    Povinec, Pavel P., E-mail: povinec@fmph.uniba.sk; Masarik, Jozef; Ješkovský, Miroslav; Kaizer, Jakub; Šivo, Alexander; Breier, Robert; Pánik, Ján; Staníček, Jaroslav; Richtáriková, Marta; Zahoran, Miroslav; Zeman, Jakub

    2015-10-15

    An Accelerator Mass Spectrometry (AMS) laboratory has been established at the Centre for Nuclear and Accelerator Technologies (CENTA) at the Comenius University in Bratislava comprising of a MC-SNICS ion source, 3 MV Pelletron tandem accelerator, and an analyzer of accelerated ions. The preparation of targets for {sup 14}C and {sup 129}I AMS measurements is described in detail. The development of AMS techniques for potassium, uranium and thorium analysis in radiopure materials required for ultra-low background underground experiments is briefly mentioned.

  9. Neuropathological research at the "Deutsche Forschungsanstalt fuer Psychiatrie" (German Institute for Psychiatric Research) in Munich (Kaiser-Wilhelm-Institute). Scientific utilization of children's organs from the "Kinderfachabteilungen" (Children's Special Departments) at Bavarian State Hospitals.

    Science.gov (United States)

    Steger, Florian

    2006-09-01

    During National Socialism, the politically motivated interest in psychiatric genetic research lead to the founding of research departments specialized in pathological-anatomical brain research, the two Kaiser Wilhelm-Institutes (KWI) in Berlin and Munich. The latter was indirectly provided with brain material by Bavarian State Hospitals, to three of which "Kinderfachabteilungen" (Special Pediatric Units) were affiliated. As children became victims of the systematically conducted child "euthanasia" in these Special Pediatric Units, this paper will address the question whether and to which extent the organs from victims of child "euthanasia" were used for (neuro-) pathological research at the KWI in Munich. By means of case studies and medical histories (with focus on the situation in Kaufbeuren-Irsee), I will argue that pediatric departments on a regular base delivered slide preparations, that the child "euthanasia" conduced in these departments systematically contributed to neuropathological research and that slide preparations from victims of child "euthanasia" were used in scientific publications after 1945.

  10. Realisation of the guidelines for faculty-internal exams at the Department of General Medicine at the University of Munich: Pushing medical exams one step ahead with IMSm.

    Science.gov (United States)

    Boeder, Niklas; Holzer, Matthias; Schelling, Jörg

    2012-01-01

    Graded exams are prerequisites for the admission to the medical state examination. Accordingly the exams must be of good quality in order to allow benchmarking with the faculty and between different universities. Criteria for good quality need to be considered - namely objectivity, validity and reliability. The guidelines for the processing of exams published by the GMA are supposed to help maintaining those criteria. In 2008 the Department of General Medicine at the University of Munich fulfils only 14 of 18 items. A review process, appropriate training of the staff and the introduction of the IMSm software were the main changes that helped to improve the 'GMA-score' to 30 fulfilled items. We see the introduction of the IMSm system as our biggest challenge ahead. IMSm helps to streamline the necessary workflow and improves their quality (e.g. by the detection of cueing, item analysis). Overall, we evaluate the steps to improve the exam process as very positive. We plan to engage co-workers outside the department to assist in the various review processes in the future. Furthermore we think it might be of value to get into contact with other departments and faculties to benefit from each other's question pools.

  11. Contributions to the 11. Geoengineering Congress in Munich. Geoengineering and energy; Beitraege zum 11. Geotechnik-Tag in Muenchen. Geotechnik und Energie

    Energy Technology Data Exchange (ETDEWEB)

    Vogt, Norbert (ed.)

    2012-11-01

    Within the eleventh geotechnics conference at 09th March, 2012 in Munich (Federal Republic of Germany), the following lectures were held: (1) New construction of the highway A44 on a new open pit dump (N. Vogt); (2) Soil liquefaction issues at mining dumps in the Lausitz (Wolfram Kudla); (3) Underfloor pumped-storage power plants in facilities of hard coal minings (Eugen Perau); (4) Geothermal energy power plant trademark (H. Haemmerle); (5) Surface settlements during the tunnel heading in the loose rock - prognosis, measurement and impact (J. Fillibeck); (6) Ring wall storages - an essential contribution to geotechnics for energy storage (M. Popp); (7) Storage basins and their geotechnical challenges (S. Messerklinger); (8) Energy from the Andes: The hydroelectric power plant La Confluencia in Chile (M. Mueller); (9) Particularities of geotechnical verifications for flat foundations of offshore wind power plants (U. Hartwig); (10) Dimensioning of piles for the foundation of offshore wind power plants (M. Achmus); (11) Offshore wind power fundaments: Practical experiences from the projects London Array and Dan Tysk (M. Horn); (12) Installation of a mono pile as a foundation structure for a tide turbine (S. Schmitz); (13) Carbon footprint - International comparison of assessment approaches at specialist foundation engineering techniques (A. Zoehrer); (14) Geotechnical assessments of upgrading power transmission lines (A. Smith).

  12. Morphology and River Monitoring - Topobathymetry as a new level of monitoring and managing the morphology at the river Isar, Munich after the flood flows 2013

    Science.gov (United States)

    Steinbacher, Frank; Schaufuß, Daniela; Aufleger, Markus; Baran, Ramona; Dobler, Wolfgang

    2014-05-01

    Topobathymetry is a new approach for the very detailed bathymetric survey of water bodies (rivers, lakes, nearshore) as well as the topographic side in a same resolution. This technique was made possible within the scope of a research project between the University of Innsbruck and Riegl LMS (Horn, Lower Austria). This airborne-operated, water-penetrating laser system capturing both sides of water's edge is considered as a technical revolution for the comprehensive and simultaneous survey and research of our countryside. Monitoring our waters area-wide and with a point density lager 20 points/m² a new data level is reached for managing them and performing research on hydraulics and morphology. By now operating the system over three years and due to the flood flows in Austria and Germany in 2013 a dataset before and after the effects of the flood could be analyzed at the river Isar. The changes monitored at the river Isar due to the flood flow will be presented as well as the new possibilities in calibrating hydro- morphologic numerical models. The project offers the city of Munich new knowledge and ways in managing inner-city river structures and planning the future of the close-to-nature approaches at the river Isar.

  13. Paving the Road for Modern Particle Therapy – What Can We Learn from the Experience Gained with Fast Neutron Therapy in Munich?

    Science.gov (United States)

    Specht, Hanno M.; Neff, Teresa; Reuschel, Waltraud; Wagner, Franz M.; Kampfer, Severin; Wilkens, Jan J.; Petry, Winfried; Combs, Stephanie E.

    2015-01-01

    While neutron therapy was a highly topical subject in the 70s and 80s, today there are only a few remaining facilities offering fast neutron therapy (FNT). Nevertheless, up to today more than 30,000 patients were treated with neutron therapy. For some indications like salivary gland tumors and malignant melanoma, there is clinical evidence that the addition of FNT leads to superior local control compared to photon treatment alone. FNT was available in Munich from 1985 until 2000 at the Reactor Neutron Therapy (RENT) facility. Patient treatment continued at the new research reactor FRM II in 2007 under improved treatment conditions, and today it can still be offered to selected patients as an individual treatment option. As there is a growing interest in high-linear energy transfer (LET) therapy with new hadron therapy centers emerging around the globe, the clinical data generated by neutron therapy might help to develop biologically driven treatment planning algorithms. Also FNT might experience its resurgence as a combinational partner of modern immunotherapies. PMID:26640777

  14. Paving the Road for Modern Particle Therapy - What Can We Learn from the Experience Gained with Fast Neutron Therapy in Munich?

    Science.gov (United States)

    Specht, Hanno M; Neff, Teresa; Reuschel, Waltraud; Wagner, Franz M; Kampfer, Severin; Wilkens, Jan J; Petry, Winfried; Combs, Stephanie E

    2015-01-01

    While neutron therapy was a highly topical subject in the 70s and 80s, today there are only a few remaining facilities offering fast neutron therapy (FNT). Nevertheless, up to today more than 30,000 patients were treated with neutron therapy. For some indications like salivary gland tumors and malignant melanoma, there is clinical evidence that the addition of FNT leads to superior local control compared to photon treatment alone. FNT was available in Munich from 1985 until 2000 at the Reactor Neutron Therapy (RENT) facility. Patient treatment continued at the new research reactor FRM II in 2007 under improved treatment conditions, and today it can still be offered to selected patients as an individual treatment option. As there is a growing interest in high-linear energy transfer (LET) therapy with new hadron therapy centers emerging around the globe, the clinical data generated by neutron therapy might help to develop biologically driven treatment planning algorithms. Also FNT might experience its resurgence as a combinational partner of modern immunotherapies.

  15. Paving the Road for Modern Particle Therapy – What can we Learn from the experience gained with Fast Neutron Therapy in Munich?

    Directory of Open Access Journals (Sweden)

    Hanno Martin Specht

    2015-11-01

    Full Text Available While neutron therapy was a highly topical subject in the 70’s and 80’s, today there are only a few remaining facilities offering fast neutron therapy. Nevertheless, up to today more than 30,000 patients were treated with neutron therapy. For some indications like salivary gland tumors and malignant melanoma there is clinical evidence that the addition of Fast Neutron Therapy (FNT leads to superior local control compared to photon treatment alone. FNT was available in Munich from 1985 until 2000 at the RENT facility (Reactor Neutron Therapy. Patient treatment continued at the new research reactor FRM II in 2007 under improved treatment conditions and today it can still be offered to selected patients as an individual treatment option. As there is a growing interest in high-linear energy transfer (LET therapy with new hadron therapy centers emerging around the globe, the clinical data generated by neutron therapy might help to develop biologically driven treatment planning algorithms. Also FNT might experience its resurgence as a combinational partner of modern immunotherapies.

  16. First operation of ATLAS using the PII linac and a comparison to tandem injection

    Energy Technology Data Exchange (ETDEWEB)

    Pardo, R.C.; Bollinger, L.M.; Billquist, P.J.; Bogaty, J.M.; Clifft, B.E.; Markovich, P.; Munson, F.H.; Shepard, K.W.; Zinkann, G.P.

    1991-12-31

    The ATLAS Positive Ion Injector (PII) is designed to replace the tandem injector for the ATLAS heavy-ion facility. When the PII project is complete, ATLAS will be able to accelerate all ions through uranium to energies above the Coulomb barrier. PII consists of an ECR ion source on a 350 kV platform and a very low-velocity superconducting linac. The PII project is nearing completion. First beam from the complete system is expected in early 1992. Beam tests and experiments using a partially completed PII linac have demonstrated that the technical design goals are being met. The results of the early beam tests and first experiments will be discussed and compared to the performance of ATLAS with tandem injection. 10 refs., 2 figs.

  17. First operation of ATLAS using the PII linac and a comparison to tandem injection

    Energy Technology Data Exchange (ETDEWEB)

    Pardo, R.C.; Bollinger, L.M.; Billquist, P.J.; Bogaty, J.M.; Clifft, B.E.; Markovich, P.; Munson, F.H.; Shepard, K.W.; Zinkann, G.P.

    1991-01-01

    The ATLAS Positive Ion Injector (PII) is designed to replace the tandem injector for the ATLAS heavy-ion facility. When the PII project is complete, ATLAS will be able to accelerate all ions through uranium to energies above the Coulomb barrier. PII consists of an ECR ion source on a 350 kV platform and a very low-velocity superconducting linac. The PII project is nearing completion. First beam from the complete system is expected in early 1992. Beam tests and experiments using a partially completed PII linac have demonstrated that the technical design goals are being met. The results of the early beam tests and first experiments will be discussed and compared to the performance of ATLAS with tandem injection. 10 refs., 2 figs.

  18. Ion mobility tandem mass spectrometry enhances performance of bottom-up proteomics.

    Science.gov (United States)

    Helm, Dominic; Vissers, Johannes P C; Hughes, Christopher J; Hahne, Hannes; Ruprecht, Benjamin; Pachl, Fiona; Grzyb, Arkadiusz; Richardson, Keith; Wildgoose, Jason; Maier, Stefan K; Marx, Harald; Wilhelm, Mathias; Becher, Isabelle; Lemeer, Simone; Bantscheff, Marcus; Langridge, James I; Kuster, Bernhard

    2014-12-01

    One of the limiting factors in determining the sensitivity of tandem mass spectrometry using hybrid quadrupole orthogonal acceleration time-of-flight instruments is the duty cycle of the orthogonal ion injection system. As a consequence, only a fraction of the generated fragment ion beam is collected by the time-of-flight analyzer. Here we describe a method utilizing postfragmentation ion mobility spectrometry of peptide fragment ions in conjunction with mobility time synchronized orthogonal ion injection leading to a substantially improved duty cycle and a concomitant improvement in sensitivity of up to 10-fold for bottom-up proteomic experiments. This enabled the identification of 7500 human proteins within 1 day and 8600 phosphorylation sites within 5 h of LC-MS/MS time. The method also proved powerful for multiplexed quantification experiments using tandem mass tags exemplified by the chemoproteomic interaction analysis of histone deacetylases with Trichostatin A.

  19. Tandem transformation of glycerol to esters.

    Science.gov (United States)

    Sotenko, Maria V; Rebroš, Martin; Sans, Victor S; Loponov, Konstantin N; Davidson, Matthew G; Stephens, Gill; Lapkin, Alexei A

    2012-12-31

    Tandem transformation of glycerol via microbial fermentation and enzymatic esterification is presented. The reaction can be performed with purified waste glycerol from biodiesel production in a continuous mode, combining continuous fermentation with membrane-supported enzymatic esterification. Continuous anaerobic fermentation was optimized resulting in the productivity of 2.4 g L⁻¹ h⁻¹ of 1,3-propanediol. Biphasic esterification of 1,3-propanediol was optimized to achieve ester yield of up to 75%. A hollow fibre membrane contactor with immobilized Rhizomucor miehei lipase was demonstrated for the continuous tandem fermentation-esterification process.

  20. 2014 CERN Accelerator Schools: Plasma Wake Acceleration

    CERN Multimedia

    2014-01-01

    A specialised school on Plasma Wake Acceleration will be held at CERN, Switzerland from 23-29 November, 2014.   This course will be of interest to staff and students in accelerator laboratories, university departments and companies working in or having an interest in the field of new acceleration techniques. Following introductory lectures on plasma and laser physics, the course will cover the different components of a plasma wake accelerator and plasma beam systems. An overview of the experimental studies, diagnostic tools and state of the art wake acceleration facilities, both present and planned, will complement the theoretical part. Topical seminars and a visit of CERN will complete the programme. Further information can be found at: http://cas.web.cern.ch/cas/PlasmaWake2014/CERN-advert.html http://indico.cern.ch/event/285444/

  1. STATUS AND RECENT PERFORMANCE OF THE ACCELERATORS THAT SERVE AS GOLD INJECTOR FOR RHIC.

    Energy Technology Data Exchange (ETDEWEB)

    AHRENS,L.; ALESSI,J.; VAN ASSELT,W.; BENJAMIN,J.; BLASKIEWICZ,M.; BRENNAN,J.M.; BROWN,K.A.; CARLSON,C.; DELONG,J.; GARDNER,C.J.; GLENN,J.W.; HAYES,T.; ROSER,T.; SMITH,K.S.; STESKI,D.; TSOUPAS,N.; ZENO,K.; ZHANG,S.Y.

    2001-06-18

    The recent successful commissioning and operation [1] of the Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Laboratory (BNL) requires the injection of gold ions of specified energy and intensity with longitudinal and transverse emittances small enough to meet the luminosity requirements of the collider. Ion beams with the desired characteristics are provided by a series of three accelerators, the Tandem, Booster and AGS. The current status and recent performance of these accelerators are reviewed in this paper.

  2. Treatment planning capability assessment of a beam shaping assembly for accelerator-based BNCT

    Energy Technology Data Exchange (ETDEWEB)

    Herrera, M.S., E-mail: herrera@tandar.cnea.gov.ar [Comision Nacional de Energia Atomica, CNEA, Av. Gral. Paz 1499, San Martin (Argentina)] [Consejo Nacional de Investigaciones Cientificas y Tecnicas, CONICET, Av. Rivadavia 191, Buenos Aires (Argentina)] [Universidad Nacional de San Martin, UNSAM, Av. 25 de Mayo y Francia Buenos Aires (Argentina); Gonzalez, S.J. [Comision Nacional de Energia Atomica, CNEA, Av. Gral. Paz 1499, San Martin (Argentina)] [Consejo Nacional de Investigaciones Cientificas y Tecnicas, CONICET, Av. Rivadavia 191, Buenos Aires (Argentina); Burlon, A.A. [Comision Nacional de Energia Atomica, CNEA, Av. Gral. Paz 1499, San Martin (Argentina)] [Universidad Nacional de San Martin, UNSAM, Av. 25 de Mayo y Francia Buenos Aires (Argentina); Minsky, D.M.; Kreiner, A.J. [Comision Nacional de Energia Atomica, CNEA, Av. Gral. Paz 1499, San Martin (Argentina)] [Consejo Nacional de Investigaciones Cientificas y Tecnicas, CONICET, Av. Rivadavia 191, Buenos Aires (Argentina)] [Universidad Nacional de San Martin, UNSAM, Av. 25 de Mayo y Francia Buenos Aires (Argentina)

    2011-12-15

    Within the frame of an ongoing project to develop a folded Tandem-Electrostatic-Quadrupole accelerator facility for Accelerator-Based Boron Neutron Capture Therapy (AB-BNCT) a theoretical study was performed to assess the treatment planning capability of different configurations of an optimized beam shaping assembly for such a facility. In particular this study aims at evaluating treatment plans for a clinical case of Glioblastoma.

  3. In situ ion irradiation/implantation studies in the HVEM-Tandem Facility at Argonne National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Allen, C.W.; Funk, L.L.; Ryan, E.A.; Taylor, A.

    1988-09-01

    The HVEM-Tandem User Facility at Argonne National Laboratory interfaces two ion accelerators, a 2 MV tandem accelerator and a 650 kV ion implanter, to a 1.2 MV high voltage electron microscope. This combination allows experiments involving simultaneous ion irradiation/ion implantation, electron irradiation and electron microscopy/electron diffraction to be performed. In addition the availability of a variety of microscope sample holders permits these as well as other types of in situ experiments to be performed at temperatures ranging from 10-1300 K, with the sample in a stressed state or with simultaneous determination of electrical resistivity of the specimen. This paper summarizes the details of the Facility which are relevant to simultaneous ion beam material modification and electron microscopy, presents several current applications and briefly describes the straightforward mechanism for potential users to access this US Department of Energy supported facility. 7 refs., 1 fig., 1 tab.

  4. High Energy Particle Accelerators

    CERN Multimedia

    Audio Productions, Inc, New York

    1960-01-01

    Film about the different particle accelerators in the US. Nuclear research in the US has developed into a broad and well-balanced program.Tour of accelerator installations, accelerator development work now in progress and a number of typical experiments with high energy particles. Brookhaven, Cosmotron. Univ. Calif. Berkeley, Bevatron. Anti-proton experiment. Negative k meson experiment. Bubble chambers. A section on an electron accelerator. Projection of new accelerators. Princeton/Penn. build proton synchrotron. Argonne National Lab. Brookhaven, PS construction. Cambridge Electron Accelerator; Harvard/MIT. SLAC studying a linear accelerator. Other research at Madison, Wisconsin, Fixed Field Alternate Gradient Focusing. (FFAG) Oakridge, Tenn., cyclotron. Two-beam machine. Comments : Interesting overview of high energy particle accelerators installations in the US in these early years. .

  5. Improved plasma accelerator

    Science.gov (United States)

    Cheng, D. Y.

    1971-01-01

    Converging, coaxial accelerator electrode configuration operates in vacuum as plasma gun. Plasma forms by periodic injections of high pressure gas that is ionized by electrical discharges. Deflagration mode of discharge provides acceleration, and converging contours of plasma gun provide focusing.

  6. Accelerator Technology Division

    Science.gov (United States)

    1992-04-01

    In fiscal year (FY) 1991, the Accelerator Technology (AT) division continued fulfilling its mission to pursue accelerator science and technology and to develop new accelerator concepts for application to research, defense, energy, industry, and other areas of national interest. This report discusses the following programs: The Ground Test Accelerator Program; APLE Free-Electron Laser Program; Accelerator Transmutation of Waste; JAERI, OMEGA Project, and Intense Neutron Source for Materials Testing; Advanced Free-Electron Laser Initiative; Superconducting Super Collider; The High-Power Microwave Program; (Phi) Factory Collaboration; Neutral Particle Beam Power System Highlights; Accelerator Physics and Special Projects; Magnetic Optics and Beam Diagnostics; Accelerator Design and Engineering; Radio-Frequency Technology; Free-Electron Laser Technology; Accelerator Controls and Automation; Very High-Power Microwave Sources and Effects; and GTA Installation, Commissioning, and Operations.

  7. 14 CFR 105.45 - Use of tandem parachute systems.

    Science.gov (United States)

    2010-01-01

    ... completed a tandem instructor course given by the manufacturer of the tandem parachute system used in the... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Use of tandem parachute systems. 105.45... (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES PARACHUTE OPERATIONS Parachute Equipment and Packing...

  8. Accelerator SIMS, a technique for the determination of stable trace elements in ultrapure materials

    Energy Technology Data Exchange (ETDEWEB)

    Ender, R.M.; Suter, M. [Eidgenoessische Technische Hochschule, Zurich (Switzerland); Doebeli, M.; Synal, H.A. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1997-09-01

    A new sputtering chamber with special precautions against sample contamination from the surroundings of the sample has been added to the AMS beamline of the tandem accelerator. This allows the detection of trace element concentrations in ultrapure materials below the ppb range in many cases. (author) 1 fig., 2 refs.

  9. Accelerators, Colliders, and Snakes

    Science.gov (United States)

    Courant, Ernest D.

    2003-12-01

    The author traces his involvement in the evolution of particle accelerators over the past 50 years. He participated in building the first billion-volt accelerator, the Brookhaven Cosmotron, which led to the introduction of the "strong-focusing" method that has in turn led to the very large accelerators and colliders of the present day. The problems of acceleration of spin-polarized protons are also addressed, with discussions of depolarizing resonances and "Siberian snakes" as a technique for mitigating these resonances.

  10. Evolution of the tandem mirror reactor concept

    Energy Technology Data Exchange (ETDEWEB)

    Carlson, G.A.; Logan, B.G.

    1982-03-09

    We discuss the evolution of the tandem mirror reactor concept from the original conceptual reactor design (1977) through the first application of the thermal barrier concept to a reactor design (1979) to the beginning of the Mirror Advanced Reactor Study (1982).

  11. M/G/∞ tandem queues

    NARCIS (Netherlands)

    Boxma, O.J.

    1984-01-01

    We consider a series of queues with Poisson input. Each queueing system contains an infinite number of service channels. The service times in each channel have a general distribution. For this M/G∞ tandem model we obtain the joint time-dependent distribution of queue length and residual service tim

  12. M/G/∞ tandem queues

    NARCIS (Netherlands)

    Boxma, O.J.

    1984-01-01

    We consider a series of queues with Poisson input. Each queueing system contains an infinite number of service channels. The service times in each channel have a general distribution. For this M/G∞ tandem model we obtain the joint time-dependent distribution of queue length and residual service tim

  13. Modelling of tandem cell temperature coefficients

    Energy Technology Data Exchange (ETDEWEB)

    Friedman, D.J. [National Renewable Energy Lab., Golden, CO (United States)

    1996-05-01

    This paper discusses the temperature dependence of the basic solar-cell operating parameters for a GaInP/GaAs series-connected two-terminal tandem cell. The effects of series resistance and of different incident solar spectra are also discussed.

  14. Evolution of orthologous tandemly arrayed gene clusters

    Directory of Open Access Journals (Sweden)

    Bertrand Denis

    2011-10-01

    Full Text Available Abstract Background Tandemly Arrayed Gene (TAG clusters are groups of paralogous genes that are found adjacent on a chromosome. TAGs represent an important repertoire of genes in eukaryotes. In addition to tandem duplication events, TAG clusters are affected during their evolution by other mechanisms, such as inversion and deletion events, that affect the order and orientation of genes. The DILTAG algorithm developed in 1 makes it possible to infer a set of optimal evolutionary histories explaining the evolution of a single TAG cluster, from an ancestral single gene, through tandem duplications (simple or multiple, direct or inverted, deletions and inversion events. Results We present a general methodology, which is an extension of DILTAG, for the study of the evolutionary history of a set of orthologous TAG clusters in multiple species. In addition to the speciation events reflected by the phylogenetic tree of the considered species, the evolutionary events that are taken into account are simple or multiple tandem duplications, direct or inverted, simple or multiple deletions, and inversions. We analysed the performance of our algorithm on simulated data sets and we applied it to the protocadherin gene clusters of human, chimpanzee, mouse and rat. Conclusions Our results obtained on simulated data sets showed a good performance in inferring the total number and size distribution of duplication events. A limitation of the algorithm is however in dealing with multiple gene deletions, as the algorithm is highly exponential in this case, and becomes quickly intractable.

  15. Optimal (batch) dispatching in a tandem queue

    NARCIS (Netherlands)

    D. van Leeuwen (Daphne); R. Núñez Queija (Rudesindo (Sindo))

    2016-01-01

    textabstractMotivated by various applications in logistics, road traffic and production management, we investigate two versions of a tandem queueing model in which the service rate of the first queue can be controlled. The objective is to keep the mean number of jobs in the second queue as low as po

  16. Tandem queue with server slow-down

    NARCIS (Netherlands)

    D.I. Miretskiy; W.R.W. Scheinhardt; M.R.H. Mandjes

    2007-01-01

    We study how rare events happen in the standard two-node tandem Jackson queue and in a generalization, the socalled slow-down network, see [2]. In the latter model the service rate of the first server depends on the number of jobs in the second queue: the first server slows down if the amount of job

  17. The CERN Accelerator School

    CERN Multimedia

    2016-01-01

    Introduction to accelerator physics The CERN Accelerator School: Introduction to Accelerator Physics, which should have taken place in Istanbul, Turkey, later this year has now been relocated to Budapest, Hungary.  Further details regarding the new hotel and dates will be made available as soon as possible on a new Indico site at the end of May.

  18. Accelerators and Dinosaurs

    CERN Multimedia

    Turner, Michael Stanley

    2003-01-01

    Using naturally occuring particles on which to research might have made accelerators become extinct. But in fact, results from astrophysics have made accelerator physics even more important. Not only are accelerators used in hospitals but they are also being used to understand nature's inner workings by searching for Higgs bosons, CP violation, neutrino mass and dark matter (2 pages)

  19. Far field acceleration

    Energy Technology Data Exchange (ETDEWEB)

    Fernow, R.C.

    1995-07-01

    Far fields are propagating electromagnetic waves far from their source, boundary surfaces, and free charges. The general principles governing the acceleration of charged particles by far fields are reviewed. A survey of proposed field configurations is given. The two most important schemes, Inverse Cerenkov acceleration and Inverse free electron laser acceleration, are discussed in detail.

  20. Acceleration: It's Elementary

    Science.gov (United States)

    Willis, Mariam

    2012-01-01

    Acceleration is one tool for providing high-ability students the opportunity to learn something new every day. Some people talk about acceleration as taking a student out of step. In actuality, what one is doing is putting a student in step with the right curriculum. Whole-grade acceleration, also called grade-skipping, usually happens between…

  1. A model-based approach to adjust microwave observations for operational applications: results of a campaign at Munich Airport in winter 2011/2012

    Directory of Open Access Journals (Sweden)

    J. Güldner

    2013-10-01

    Full Text Available In the frame of the project "LuFo iPort VIS" which focuses on the implementation of a site-specific visibility forecast, a field campaign was organised to offer detailed information to a numerical fog model. As part of additional observing activities, a 22-channel microwave radiometer profiler (MWRP was operating at the Munich Airport site in Germany from October 2011 to February 2012 in order to provide vertical temperature and humidity profiles as well as cloud liquid water information. Independently from the model-related aims of the campaign, the MWRP observations were used to study their capabilities to work in operational meteorological networks. Over the past decade a growing quantity of MWRP has been introduced and a user community (MWRnet was established to encourage activities directed at the set up of an operational network. On that account, the comparability of observations from different network sites plays a fundamental role for any applications in climatology and numerical weather forecast. In practice, however, systematic temperature and humidity differences (bias between MWRP retrievals and co-located radiosonde profiles were observed and reported by several authors. This bias can be caused by instrumental offsets and by the absorption model used in the retrieval algorithms as well as by applying a non-representative training data set. At the Lindenberg observatory, besides a neural network provided by the manufacturer, a measurement-based regression method was developed to reduce the bias. These regression operators are calculated on the basis of coincident radiosonde observations and MWRP brightness temperature (TB measurements. However, MWRP applications in a network require comparable results at just any site, even if no radiosondes are available. The motivation of this work is directed to a verification of the suitability of the operational local forecast model COSMO-EU of the Deutscher Wetterdienst (DWD for the calculation

  2. The Accelerator Reliability Forum

    CERN Document Server

    Lüdeke, Andreas; Giachino, R

    2014-01-01

    A high reliability is a very important goal for most particle accelerators. The biennial Accelerator Reliability Workshop covers topics related to the design and operation of particle accelerators with a high reliability. In order to optimize the over-all reliability of an accelerator one needs to gather information on the reliability of many different subsystems. While a biennial workshop can serve as a platform for the exchange of such information, the authors aimed to provide a further channel to allow for a more timely communication: the Particle Accelerator Reliability Forum [1]. This contribution will describe the forum and advertise it’s usage in the community.

  3. The Munich Shoulder Questionnaire (MSQ: development and validation of an effective patient-reported tool for outcome measurement and patient safety in shoulder surgery

    Directory of Open Access Journals (Sweden)

    Schmidutz Florian

    2012-05-01

    Full Text Available Abstract Background Outcome measurement in shoulder surgery is essential to evaluate the patient safety and treatment efficiency. Currently this is jeopardized by the fact that most patient-reported self-assessment instruments are not comparable. Hence, the aim was to develop a reliable self-assessment questionnaire which allows an easy follow-up of patients. The questionnaire also allows the calculation of 3 well established scoring systems, i.e. the Shoulder Pain and Disability Index (SPADI, the Constant-Murley Score (CMS, and the Disabilities of the Arm, Shoulder and Hand (DASH Score. The subjective and objective items of these three systems were condensed into a single 30-questions form and validated against the original questionnaires. Methods A representative collective of patients of our shoulder clinic was asked to fill in the newly designed self-assessment Munich Shoulder Questionnaire (MSQ. At the same time, the established questionnaires for self-assessment of CONSTANT, SPADI and DASH scores were handed out. The obtained results were compared by linear regression analysis. Results Fifty one patients completed all questionnaires. The correlation coefficients of the results were r = 0.91 for the SPADI, r = -0.93 for the DASH and r = 0.94 for the CMS scoring system, respectively. Conclusions We developed an instrument which allows a quantitative self-assessment of shoulder function. It provides compatible data sets for the three most popular shoulder function scoring systems by one single, short 30-item. This instrument can be used by shoulder surgeons to effectively monitor the outcome, safety and quality of their treatment and also compare the results to published data in the literature.

  4. The Doktabörse – an innovative online platform for research projects at the medical faculty of the LMU Munich

    Directory of Open Access Journals (Sweden)

    Nicolai, Leo

    2017-08-01

    Full Text Available Introduction: One of the most important extracurricular aspects of medical studies in Germany is a research thesis completed by most students. This research project often times conveys relevant competencies for the physician’s role as scientist. Nevertheless, the choice of the right project remains a challenge. Reasons for this are among others, missing structures for a comprehensive overview of research groups and their respective projects.Description of the project: We developed the online platform as an online marketplace for doctoral research projects. The platform enables authorized researchers to create working groups and upload, deactivate and change research projects within their institute. For interested students, a front end with integrated search function displays these projects in a structured and well-arranged way. In parallel, the provides for a comprehensive overview of research at the medical faculty. We evaluated Researchers‘ and students‘ use of the platform. Results: 96,6% of students participating in the evaluation (n=400 were in favor of a centralized research platform at the medical faculty. The platform grew at a steady pace and included 120 research groups in June 2016. The students appreciated the structure and design of the Two thirds of all uploaded projects matched successfully with doctoral students via the platform and over 94% of researchers stated that they did not need technical assistance with uploading projects and handling the platform. Discussion: The represents an innovative and well accepted platform for doctoral research projects. The platform is perceived positively by researchers and students alike. However, students criticized limited extent and timeliness of offered projects.In addition, the platform serves as databank of research at the medical faculty of the LMU Munich. The future potential of this platform is to provide for an integrated management solution of doctoral thesis projects

  5. Development of an explosive detection system using a proton accelerator

    CERN Document Server

    Cho, Y S; Lee, J H

    2002-01-01

    The technology of explosive detection using radiation had been studied. On the basis that explosives has nitrogen atoms, the proof of principle experiments had been performed with the gamma ray which interacts with nitrogen atoms. The production of the gamma ray had been confirmed and, the scattered gamma ray from nitrogen had been observed in the experiment at Seoul National University. According to the experimental results, the specifications of the accelerator had been determined, 1.8MeV and 10mA. For a long-life time, a TCP type ion source using rf power have been developed. A tandem type accelerator had been chosen, and the important technologies, accelerating column and high voltage power supply, had been developed. On the basis of these technologies, the 1MV tandem accelerator had been constructed. The production process of C-13 film had been developed, and a 20kW water-cooled target had been fabricated. For gamma ray detection, a array detector with 9 BGO had been constructed, and the SW had been deve...

  6. Coupled operation of the Oak Ridge isochronous cyclotron and the 25 MV tandem

    Energy Technology Data Exchange (ETDEWEB)

    Lord, R.S.; Ball, J.B.; Beckers, R.M.; Cleary, T.P.; Hudson, E.D.; Ludemann, C.A.; Martin, J.A.; Milner, W.T.; Mosko, S.W.; Ziegler, N.F.

    1981-01-01

    Coupled operation of the 25 MV tandem and the Oak Ridge Isochronous Cyclotron (ORIC) was achieved on January 27, 1981. A beam of 38 MeV /sup 16/O/sup 2 +/ was injected into ORIC, stripped to 8/sup +/ and accelerated to 324 MeV. Shortly afterwards, the energy was increased to the maximum design value of 25 MeV/amu (400 MeV). A spectrum taken of the scattering of this beam from a thin /sup 208/Pb target in the broad range spectrograh exhibited a resolution of 115 keV (FWHM). Performance of the system was in close agreement with that predicted from calculations.

  7. Industrial Application of Accelerators

    CERN Document Server

    CERN. Geneva

    2017-01-01

    At CERN, we are very familiar with large, high energy particle accelerators. However, in the world outside CERN, there are more than 35000 accelerators which are used for applications ranging from treating cancer, through making better electronics to removing harmful micro-organisms from food and water. These are responsible for around $0.5T of commerce each year. Almost all are less than 20 MeV and most use accelerator types that are somewhat different from what is at CERN. These lectures will describe some of the most common applications, some of the newer applications in development and the accelerator technology used for them. It will also show examples of where technology developed for particle physics is now being studied for these applications. Rob Edgecock is a Professor of Accelerator Science, with a particular interest in the medical applications of accelerators. He works jointly for the STFC Rutherford Appleton Laboratory and the International Institute for Accelerator Applications at the Univer...

  8. Industrial Application of Accelerators

    CERN Document Server

    CERN. Geneva

    2017-01-01

    At CERN, we are very familiar with large, high energy particle accelerators. However, in the world outside CERN, there are more than 35000 accelerators which are used for applications ranging from treating cancer, through making better electronics to removing harmful micro-organisms from food and water. These are responsible for around $0.5T of commerce each year. Almost all are less than 20 MeV and most use accelerator types that are somewhat different from what is at CERN. These lectures will describe some of the most common applications, some of the newer applications in development and the accelerator technology used for them. It will also show examples of where technology developed for particle physics is now being studied for these applications. Rob Edgecock is a Professor of Accelerator Science, with a particular interest in the medical applications of accelerators. He works jointly for the STFC Rutherford Appleton Laboratory and the International Institute for Accelerator Applications at the Uni...

  9. Acceleration in astrophysics

    Energy Technology Data Exchange (ETDEWEB)

    Colgate, S.A.

    1993-12-31

    The origin of cosmic rays and applicable laboratory experiments are discussed. Some of the problems of shock acceleration for the production of cosmic rays are discussed in the context of astrophysical conditions. These are: The presumed unique explanation of the power law spectrum is shown instead to be a universal property of all lossy accelerators; the extraordinary isotropy of cosmic rays and the limited diffusion distances implied by supernova induced shock acceleration requires a more frequent and space-filling source than supernovae; the near perfect adiabaticity of strong hydromagnetic turbulence necessary for reflecting the accelerated particles each doubling in energy roughly 10{sup 5} to {sup 6} scatterings with negligible energy loss seems most unlikely; the evidence for acceleration due to quasi-parallel heliosphere shocks is weak. There is small evidence for the expected strong hydromagnetic turbulence, and instead, only a small number of particles accelerate after only a few shock traversals; the acceleration of electrons in the same collisionless shock that accelerates ions is difficult to reconcile with the theoretical picture of strong hydromagnetic turbulence that reflects the ions. The hydromagnetic turbulence will appear adiabatic to the electrons at their much higher Larmor frequency and so the electrons should not be scattered incoherently as they must be for acceleration. Therefore the electrons must be accelerated by a different mechanism. This is unsatisfactory, because wherever electrons are accelerated these sites, observed in radio emission, may accelerate ions more favorably. The acceleration is coherent provided the reconnection is coherent, in which case the total flux, as for example of collimated radio sources, predicts single charge accelerated energies much greater than observed.

  10. Negative hydrogen ion sources for accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Moehs, D.P.; /Fermilab; Peters, J.; /DESY; Sherman, J.; /Los Alamos

    2005-08-01

    A variety of H{sup -} ion sources are in use at accelerator laboratories around the world. A list of these ion sources includes surface plasma sources with magnetron, Penning and surface converter geometries as well as magnetic-multipole volume sources with and without cesium. Just as varied is the means of igniting and maintaining magnetically confined plasmas. Hot and cold cathodes, radio frequency, and microwave power are all in use, as well as electron tandem source ignition. The extraction systems of accelerator H{sup -} ion sources are highly specialized utilizing magnetic and electric fields in their low energy beam transport systems to produce direct current, as well as pulsed and/or chopped beams with a variety of time structures. Within this paper, specific ion sources utilized at accelerator laboratories shall be reviewed along with the physics of surface and volume H{sup -} production in regard to source emittance. Current research trends including aperture modeling, thermal modeling, surface conditioning, and laser diagnostics will also be discussed.

  11. Particle-accelerator decommissioning

    Energy Technology Data Exchange (ETDEWEB)

    Opelka, J.H.; Mundis, R.L.; Marmer, G.J.; Peterson, J.M.; Siskind, B.; Kikta, M.J.

    1979-12-01

    Generic considerations involved in decommissioning particle accelerators are examined. There are presently several hundred accelerators operating in the United States that can produce material containing nonnegligible residual radioactivity. Residual radioactivity after final shutdown is generally short-lived induced activity and is localized in hot spots around the beam line. The decommissioning options addressed are mothballing, entombment, dismantlement with interim storage, and dismantlement with disposal. The recycle of components or entire accelerators following dismantlement is a definite possibility and has occurred in the past. Accelerator components can be recycled either immediately at accelerator shutdown or following a period of storage, depending on the nature of induced activation. Considerations of cost, radioactive waste, and radiological health are presented for four prototypic accelerators. Prototypes considered range from small accelerators having minimal amounts of radioactive mmaterial to a very large accelerator having massive components containing nonnegligible amounts of induced activation. Archival information on past decommissionings is presented, and recommendations concerning regulations and accelerator design that will aid in the decommissioning of an accelerator are given.

  12. IBA using a small tandem and a single-ended Van de Graaff

    Science.gov (United States)

    Arai, E.; Oguri, Y.; Ogawa, M.

    1990-01-01

    Using an NEC 5SDH-2 tandem and an upgraded KN-4000 single-ended Van de Graaff machine we are investigating the depth profiles of 1,2H, 4He and 6,7Li which have been implanted or dispersed into silicon wafers, SiO 2/Si, SiO 2/magnetic bubble garnet, soda-lime glass and stainless steel. The tandem is used to generate an 8 MeV 16O beam for ERD measurements of these light elements and also a 15N 4+ beam for profiling hydrogen by means of the 1H( 15N, αγ) 12C reaction. The Van de Graaff has a maximum terminal voltage of 4.75 MV and accelerates 15N 2+ ions for 1H profiling and 3He + ions for highly sensitive 2H measurements by means of the 2H( 3He, pα) reaction. An RBS investigation is running instead of PIXE experiments which have been terminated some years ago. We are using two types of homemade cold-cathode Penning-type ion source (PIG). The one has a side-extraction design for the tandem, and the other is an end-extraction source for the Van de Graaff. Owing to very low gas consumption, both sources are suitable for generation of ions of expensive isotopes such as 3He and 15N. We will report the experience with IBA using both types of electrostatic machines.

  13. Mechanically stacked concentrator tandem solar cells

    Science.gov (United States)

    Andreev, V. M.; Rumyantsev, V. D.; Karlina, L. B.; Kazantsev, A. B.; Khvostikov, V. P.; Shvarts, M. Z.; Sorokina, S. V.

    1995-01-01

    Four-terminal mechanically stacked solar cells were developed for advanced space arrays with line-focus reflective concentrators. The top cells are based on AlGaAs/GaAs multilayer heterostructures prepared by low temperature liquid phase epitaxy. The bottom cells are based on heteroepitaxial InP/InGaAs liquid phase epitaxy or on homo-junction GaSb, Zn-diffused structures. The sum of the highest reached efficiencies of the top and bottom cells is 29.4 percent. The best four-terminal tandems have an efficiency of 27 to 28 percent. Solar cells were irradiated with 1 MeV electrons and their performances were determined as a function of fluence up to 10(exp 16) cm(exp-2). It was shown that the radiation resistance of developed tandem cells is similar to the most radiative stable AlGaAs/GaAs cells with a thin p-GaAs photoactive layer.

  14. Leaky Fermi accelerators

    CERN Document Server

    Shah, Kushal; Rom-Kedar, Vered; Turaev, Dmitry

    2015-01-01

    A Fermi accelerator is a billiard with oscillating walls. A leaky accelerator interacts with an environment of an ideal gas at equilibrium by exchange of particles through a small hole on its boundary. Such interaction may heat the gas: we estimate the net energy flow through the hole under the assumption that the particles inside the billiard do not collide with each other and remain in the accelerator for sufficiently long time. The heat production is found to depend strongly on the type of the Fermi accelerator. An ergodic accelerator, i.e. one which has a single ergodic component, produces a weaker energy flow than a multi-component accelerator. Specifically, in the ergodic case the energy gain is independent of the hole size, whereas in the multi-component case the energy flow may be significantly increased by shrinking the hole size.

  15. Accelerator reliability workshop

    Energy Technology Data Exchange (ETDEWEB)

    Hardy, L.; Duru, Ph.; Koch, J.M.; Revol, J.L.; Van Vaerenbergh, P.; Volpe, A.M.; Clugnet, K.; Dely, A.; Goodhew, D

    2002-07-01

    About 80 experts attended this workshop, which brought together all accelerator communities: accelerator driven systems, X-ray sources, medical and industrial accelerators, spallation sources projects (American and European), nuclear physics, etc. With newly proposed accelerator applications such as nuclear waste transmutation, replacement of nuclear power plants and others. Reliability has now become a number one priority for accelerator designers. Every part of an accelerator facility from cryogenic systems to data storage via RF systems are concerned by reliability. This aspect is now taken into account in the design/budget phase, especially for projects whose goal is to reach no more than 10 interruptions per year. This document gathers the slides but not the proceedings of the workshop.

  16. Accelerator and radiation physics

    CERN Document Server

    Basu, Samita; Nandy, Maitreyee

    2013-01-01

    "Accelerator and radiation physics" encompasses radiation shielding design and strategies for hadron therapy accelerators, neutron facilities and laser based accelerators. A fascinating article describes detailed transport theory and its application to radiation transport. Detailed information on planning and design of a very high energy proton accelerator can be obtained from the article on radiological safety of J-PARC. Besides safety for proton accelerators, the book provides information on radiological safety issues for electron synchrotron and prevention and preparedness for radiological emergencies. Different methods for neutron dosimetry including LET based monitoring, time of flight spectrometry, track detectors are documented alongwith newly measured experimental data on radiation interaction with dyes, polymers, bones and other materials. Design of deuteron accelerator, shielding in beam line hutches in synchrotron and 14 MeV neutron generator, various radiation detection methods, their characteriza...

  17. Cold Climate Heat Pumps Using Tandem Compressors

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Bo [ORNL; Abdelaziz, Omar [ORNL; Rice, C Keith [ORNL; Baxter, Van D [ORNL

    2016-01-01

    In cold climate zones, e.g. ASHRAE climate regions IV and V, conventional electric air-source heat pumps (ASHP) do not work well, due to high compressor discharge temperatures, large pressure ratios and inadequate heating capacities at low ambient temperatures. Consequently, significant use of auxiliary strip heating is required to meet the building heating load. We introduce innovative ASHP technologies as part of continuing efforts to eliminate auxiliary strip heat use and maximize heating COP with acceptable cost-effectiveness and reliability. These innovative ASHP were developed using tandem compressors, which are capable of augmenting heating capacity at low temperatures and maintain superior part-load operation efficiency at moderate temperatures. Two options of tandem compressors were studied; the first employs two identical, single-speed compressors, and the second employs two identical, vapor-injection compressors. The investigations were based on system modeling and laboratory evaluation. Both designs have successfully met the performance criteria. Laboratory evaluation showed that the tandem, single-speed compressor ASHP system is able to achieve heating COP = 4.2 at 47 F (8.3 C), COP = 2.9 at 17 F (-8.3 C), and 76% rated capacity and COP = 1.9 at -13 F (-25 C). This yields a HSPF = 11.0 (per AHRI 210/240). The tandem, vapor-injection ASHP is able to reach heating COP = 4.4 at 47 F, COP = 3.1 at 17 F, and 88% rated capacity and COP = 2.0 at -13 F. This yields a HSPF = 12.0. The system modeling and further laboratory evaluation are presented in the paper.

  18. Power Converters for Accelerators

    CERN Document Server

    Visintini, R

    2015-01-01

    Particle accelerators use a great variety of power converters for energizing their sub-systems; while the total number of power converters usually depends on the size of the accelerator or combination of accelerators (including the experimental setup), the characteristics of power converters depend on their loads and on the particle physics requirements: this paper aims to provide an overview of the magnet power converters in use in several facilities worldwide.

  19. Miniaturization Techniques for Accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Spencer, James E.

    2003-05-27

    The possibility of laser driven accelerators [1] suggests the need for new structures based on micromachining and integrated circuit technology because of the comparable scales. Thus, we are exploring fully integrated structures including sources, optics (for both light and particle) and acceleration in a common format--an accelerator-on-chip (AOC). Tests suggest a number of preferred materials and techniques but no technical or fundamental roadblocks at scales of order 1 {micro}m or larger.

  20. TandEM: Titan and Enceladus mission

    Science.gov (United States)

    Coustenis, A.; Atreya, S.K.; Balint, T.; Brown, R.H.; Dougherty, M.K.; Ferri, F.; Fulchignoni, M.; Gautier, D.; Gowen, R.A.; Griffith, C.A.; Gurvits, L.I.; Jaumann, R.; Langevin, Y.; Leese, M.R.; Lunine, J.I.; McKay, C.P.; Moussas, X.; Muller-Wodarg, I.; Neubauer, F.; Owen, T.C.; Raulin, F.; Sittler, E.C.; Sohl, F.; Sotin, C.; Tobie, G.; Tokano, T.; Turtle, E.P.; Wahlund, J.-E.; Waite, J.H.; Baines, K.H.; Blamont, J.; Coates, A.J.; Dandouras, I.; Krimigis, T.; Lellouch, E.; Lorenz, R.D.; Morse, A.; Porco, C.C.; Hirtzig, M.; Saur, J.; Spilker, T.; Zarnecki, J.C.; Choi, E.; Achilleos, N.; Amils, R.; Annan, P.; Atkinson, D.H.; Benilan, Y.; Bertucci, C.; Bezard, B.; Bjoraker, G.L.; Blanc, M.; Boireau, L.; Bouman, J.; Cabane, M.; Capria, M.T.; Chassefiere, E.; Coll, P.; Combes, M.; Cooper, J.F.; Coradini, A.; Crary, F.; Cravens, T.; Daglis, I.A.; de Angelis, E.; De Bergh, C.; de Pater, I.; Dunford, C.; Durry, G.; Dutuit, O.; Fairbrother, D.; Flasar, F.M.; Fortes, A.D.; Frampton, R.; Fujimoto, M.; Galand, M.; Grasset, O.; Grott, M.; Haltigin, T.; Herique, A.; Hersant, F.; Hussmann, H.; Ip, W.; Johnson, R.; Kallio, E.; Kempf, S.; Knapmeyer, M.; Kofman, W.; Koop, R.; Kostiuk, T.; Krupp, N.; Kuppers, M.; Lammer, H.; Lara, L.-M.; Lavvas, P.; Le, Mouelic S.; Lebonnois, S.; Ledvina, S.; Li, J.; Livengood, T.A.; Lopes, R.M.; Lopez-Moreno, J. -J.; Luz, D.; Mahaffy, P.R.; Mall, U.; Martinez-Frias, J.; Marty, B.; McCord, T.; Salvan, C.M.; Milillo, A.; Mitchell, D.G.; Modolo, R.; Mousis, O.; Nakamura, M.; Neish, C.D.; Nixon, C.A.; Mvondo, D.N.; Orton, G.; Paetzold, M.; Pitman, J.; Pogrebenko, S.; Pollard, W.; Prieto-Ballesteros, O.; Rannou, P.; Reh, K.; Richter, L.; Robb, F.T.; Rodrigo, R.; Rodriguez, S.; Romani, P.; Bermejo, M.R.; Sarris, E.T.; Schenk, P.; Schmitt, B.; Schmitz, N.; Schulze-Makuch, D.; Schwingenschuh, K.; Selig, A.; Sicardy, B.; Soderblom, L.; Spilker, L.J.; Stam, D.; Steele, A.; Stephan, K.; Strobel, D.F.; Szego, K.; Szopa,

    2009-01-01

    TandEM was proposed as an L-class (large) mission in response to ESA's Cosmic Vision 2015-2025 Call, and accepted for further studies, with the goal of exploring Titan and Enceladus. The mission concept is to perform in situ investigations of two worlds tied together by location and properties, whose remarkable natures have been partly revealed by the ongoing Cassini-Huygens mission. These bodies still hold mysteries requiring a complete exploration using a variety of vehicles and instruments. TandEM is an ambitious mission because its targets are two of the most exciting and challenging bodies in the Solar System. It is designed to build on but exceed the scientific and technological accomplishments of the Cassini-Huygens mission, exploring Titan and Enceladus in ways that are not currently possible (full close-up and in situ coverage over long periods of time). In the current mission architecture, TandEM proposes to deliver two medium-sized spacecraft to the Saturnian system. One spacecraft would be an orbiter with a large host of instruments which would perform several Enceladus flybys and deliver penetrators to its surface before going into a dedicated orbit around Titan alone, while the other spacecraft would carry the Titan in situ investigation components, i.e. a hot-air balloon (Montgolfi??re) and possibly several landing probes to be delivered through the atmosphere. ?? Springer Science + Business Media B.V. 2008.

  1. Flow field interactions between two tandem cyclists

    Science.gov (United States)

    Barry, Nathan; Burton, David; Sheridan, John; Thompson, Mark; Brown, Nicholas A. T.

    2016-12-01

    Aerodynamic drag is the primary resistive force acting on cyclists at racing speeds. Many events involve cyclists travelling in very close proximity. Previous studies have shown that interactions result in significant drag reductions for inline cyclists. However, the interaction between cyclist leg position (pedalling) and the vortical flow structures that contribute significantly to the drag on an isolated cyclist has not previously been quantified or described for tandem cyclists of varying separation. To this end, scale model cyclists were constructed for testing in a water channel for inline tandem configurations. Particle image velocimetry was used to capture time-averaged velocity fields around two tandem cyclists. Perhaps surprisingly, the wake of a trailing cyclist maintains strong similarity to the characteristic wake of a single cyclist despite a significant disturbance to the upstream flow. Together with streamwise velocity measurements through the wake and upstream of the trailing cyclist, this work supports previous findings, which showed that the trailing cyclist drag reduction is primarily due to upstream sheltering effects reducing the stagnation pressure on forward-facing surfaces.

  2. SIRIUS – A new 6 MV accelerator system for IBA and AMS at ANSTO

    Energy Technology Data Exchange (ETDEWEB)

    Pastuovic, Zeljko, E-mail: zkp@ansto.gov.au; Button, David; Cohen, David; Fink, David; Garton, David; Hotchkis, Michael; Ionescu, Mihail; Long, Shane; Levchenko, Vladimir; Mann, Michael; Siegele, Rainer; Smith, Andrew; Wilcken, Klaus

    2016-03-15

    The Centre for Accelerator Science (CAS) facility at ANSTO has been expanded with a new 6 MV tandem accelerator system supplied by the National Electrostatic Corporation (NEC). The beamlines, end-stations and data acquisition software for the accelerator mass spectrometry (AMS) were custom built by NEC for rare isotope mass spectrometry, while the beamlines with end-stations for the ion beam analysis (IBA) are largely custom designed at ANSTO. An overview of the 6 MV system and its performance during testing and commissioning phase is given with emphasis on the IBA end-stations and their applications for materials modification and characterisation.

  3. SIRIUS - A new 6 MV accelerator system for IBA and AMS at ANSTO

    Science.gov (United States)

    Pastuovic, Zeljko; Button, David; Cohen, David; Fink, David; Garton, David; Hotchkis, Michael; Ionescu, Mihail; Long, Shane; Levchenko, Vladimir; Mann, Michael; Siegele, Rainer; Smith, Andrew; Wilcken, Klaus

    2016-03-01

    The Centre for Accelerator Science (CAS) facility at ANSTO has been expanded with a new 6 MV tandem accelerator system supplied by the National Electrostatic Corporation (NEC). The beamlines, end-stations and data acquisition software for the accelerator mass spectrometry (AMS) were custom built by NEC for rare isotope mass spectrometry, while the beamlines with end-stations for the ion beam analysis (IBA) are largely custom designed at ANSTO. An overview of the 6 MV system and its performance during testing and commissioning phase is given with emphasis on the IBA end-stations and their applications for materials modification and characterisation.

  4. Materials science symposium 'heavy ion science in tandem energy region'

    Energy Technology Data Exchange (ETDEWEB)

    Iwamoto, Akira; Yoshida, Tadashi; Takeuchi, Suehiro (eds.) [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2001-11-01

    The facility of the JAERI tandem accelerator and its booster has been contributing to obtain plenty of fruitful results in the fields of nuclear physics, nuclear chemistry, atomic and solid state physics and materials science, taking an advantage of its prominent performances of heavy ion acceleration. The previous meeting held in 1999 also offered an opportunity to scientists from all over the heavy ion science fields, including nuclear physics, solid state physics and cross-field physics to have active discussions. This meeting included oral presentations with a new plan and with a new scope of fields expected from now on, as an occasion for opening the 21st century in heavy ion science. The 50 of the presented papers are indexed individually. (J.P.N.)

  5. FFAGS for rapid acceleration

    Energy Technology Data Exchange (ETDEWEB)

    Carol J. Johnstone and Shane Koscielniak

    2002-09-30

    When large transverse and longitudinal emittances are to be transported through a circular machine, extremely rapid acceleration holds the advantage that the beam becomes immune to nonlinear resonances because there is insufficient time for amplitudes to build up. Uncooled muon beams exhibit large emittances and require fast acceleration to avoid decay losses and would benefit from this style of acceleration. The approach here employs a fixed-field alternating gradient or FFAG magnet structure and a fixed frequency acceleration system. Acceptance is enhanced by the use only of linear lattice elements, and fixed-frequency rf enables the use of cavities with large shunt resistance and quality factor.

  6. FFAGS FOR MUON ACCELERATION.

    Energy Technology Data Exchange (ETDEWEB)

    BERG,J.S.KAHN,S.PALMER,R.TRBOJEVIC,D.JOHNSTONE,C.KEIL,Y.OGITSU,T.OHMORI,C.SESSLER,A.KOSCIELNIAK,S.

    2003-06-26

    Due to their finite lifetime, muons must be accelerated very rapidly. It is challenging to make the magnets ramp fast enough to accelerate in a synchrotron, and accelerating in a linac is very expensive. One can use a recirculating accelerator (like CEBAF), but one needs a different arc for each turn, and this limits the number of turns one can use to accelerate, and therefore requires significant amounts of RF to achieve the desired energy gain. An alternative method for muon acceleration is using a fixed field alternating gradient (FFAG) accelerator. Such an accelerator has a very large energy acceptance (a factor of two or three), allowing one to use the same arc with a magnetic field that is constant over time. Thus, one can in principle make as many turns as one can tolerate due to muon decay, therefore reducing the RF cost without increasing the arc cost. This paper reviews the current status of research into the design of FFAGs for muon acceleration. Several current designs are described and compared. General design considerations are also discussed.

  7. High Gradient Accelerator Research

    Energy Technology Data Exchange (ETDEWEB)

    Temkin, Richard [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States). Dept. of Physics. Plasma Science and Fusion Center

    2016-07-12

    The goal of the MIT program of research on high gradient acceleration is the development of advanced acceleration concepts that lead to a practical and affordable next generation linear collider at the TeV energy level. Other applications, which are more near-term, include accelerators for materials processing; medicine; defense; mining; security; and inspection. The specific goals of the MIT program are: • Pioneering theoretical research on advanced structures for high gradient acceleration, including photonic structures and metamaterial structures; evaluation of the wakefields in these advanced structures • Experimental research to demonstrate the properties of advanced structures both in low-power microwave cold test and high-power, high-gradient test at megawatt power levels • Experimental research on microwave breakdown at high gradient including studies of breakdown phenomena induced by RF electric fields and RF magnetic fields; development of new diagnostics of the breakdown process • Theoretical research on the physics and engineering features of RF vacuum breakdown • Maintaining and improving the Haimson / MIT 17 GHz accelerator, the highest frequency operational accelerator in the world, a unique facility for accelerator research • Providing the Haimson / MIT 17 GHz accelerator facility as a facility for outside users • Active participation in the US DOE program of High Gradient Collaboration, including joint work with SLAC and with Los Alamos National Laboratory; participation of MIT students in research at the national laboratories • Training the next generation of Ph. D. students in the field of accelerator physics.

  8. Baron von Zach's business relations with the Munich entrepreneur Joseph von Utzschneider (German Title: Geschäftsbeziehungen des Barons von Zach zu dem Münchner Unternehmer Joseph von Utzschneider)

    Science.gov (United States)

    Schneider, Ivo

    The relationship between the astronomer von Zach on the one side and the entrepreneur Joseph von Utzschneider and his partner Georg von Reichenbach on the other dates presumably from the year 1807 when Zach spent two months in Munich. Already in the same year Zach had ordered an instrument for himself and began to solicit business for the institute of Reichenbach, Utzschneider, and Liebherr, which was founded in 1804. One of the clients canvassed by Zach was the director of the observatory in Naples Zuccari. Zuccari had ordered the whole equipment for the new observatory from this institute in 1813. The instruments for Naples, which were completed in 1814, were sent accompanied by Reichenbach by land and sea to their destination where Reichenbach supervised their setup. At that time Reichenbach had separated from Utzschneider who kept the optical institute in Benediktbeuern with his new partner Joseph von Fraunhofer whereas Reichenbach became owner of the mathematical-mechanical institute in Munich. For personal and economical reasons Utzschneider began soon after to produce not only optical glass but also optical devices similar to those offered by Reichenbach. As soon as two institutes in Munich competed against each other on the market for sophisticated geodetical and astronomical instruments Zach sided with Utzschneider. Zach's main professional argument for this decision was that both competitors got the optical glass for their instruments from Utzschneider's optical institute in Benediktbeuern. This meant that Utzschneider had first choice and so the optical part of his instruments could be considered as better than that of Reichenbach`s instruments. Zach's role as an agent in Italy and France for the sale of products coming from Utzschneider's manufactories is highlighted by three of Zach's letters to Utzschneider from 1817 and 1818, two of which are reproduced here for the first time.

  9. Iglesia de San Bernardo, Munich

    Directory of Open Access Journals (Sweden)

    Haindl, Friederich F.

    1963-06-01

    Full Text Available In plan form this church has the shape of an irregular pentagon. The external walls are in brick and are crowned by a reinforced encircling concrete polygonal hoop. The surfaces of the walls are faced both on the outside and internally. The roof consists of metal girders resting at the convergence of the walls on the concrete encircling girder. Timber trellice joists join these girders. Inside, the maximum height of the ceiling is 25 ms, and the continuity of the walls is broken by prefabricated panels carrying glazing, which provides suitable daylight illumination. The roof structure is lined with wood, to give it an interior shape reminiscent of a large tent. The benches for the congregation are arranged in four groups round the altar. The vicarage is older than the church structure, and is built on the same level. There is also a large church hall, suitable for a variety of functions allied to the chapel. Slightly linked with the church body is a 37 ms high tower. The whole design is outstanding because of its clear organic relationship of forms and volumes.La iglesia es una construcción central, cuya planta adopta la forma de un pentágono irregular Los muros exteriores son de fábrica de ladrillo y están coronados por un zuncho de atado de hormigón armado. Sus paramentos van enfoscados tanto por dentro como por fuera. La cubierta está constituida a base de vigas metálicas que se entregan en las esquinas —sobre el zuncho de hormigón—, entre las que se acoplan vigas de celosía, de madera. El interior, cuya máxima altura de techo es 25 m, nos muestra sus paredes interrumpidas por paneles prefabricados de hormigón, acristalados, coa objeto de conseguir una adecuada iluminación. El techo va revestido con madera formando como tienda de campaña. Los bancos están colocados en cuatro grupos alrededor del altar. Más antigua, y al mismo nivel de la iglesia, se halla la casa parroquial, y un gran salón para diferentes actividades; unida ligeramente a éste, se levanta la torre de 37 m de altura. Destaca el conjunto por su clara ordenación y acertado juego de volúmenes.

  10. Restaurante Tantris Munich - Alemania Federal

    Directory of Open Access Journals (Sweden)

    Dahinden, Justus

    1974-11-01

    Full Text Available The success of this restaurant, situated in the capital of a province where there is an abundance of excellent eating places, is due to the fact that in order to incite the imagination of the customer it provides an exquisite cooking together with an attractive architectural decoration and pleasant atmosphere. This is achieved by a successful combination of materials, polychrome, furniture, different levelling of sections, live plants and further - direct view into the kitchen which thus is open to the curiosity of the client. The exterior of the building with its concrete walls and copper roofs constitutes an interesting contrast to the surrounding constructions, another positive feature that contributes to make an impact on the guests.El éxito de este restaurante, situado en la capital de una región donde abundan los locales que ofrecen comidas de calidad, estriba en que, a una cocina selecta une la decoración y ambientación más adecuadas para estimular la fantasía del cliente. Esto se consigue mediante la utilización acertada de materiales, policromía, mobiliario, zonificación a distintos niveles y ornamentación vegetal viva en su interior, además de la visión directa de la cocina, que está abierta a la curiosidad del comensal. La fisonomía exterior del edificio, con sus paramentos de hormigón y cubierta de cobre, contrastando con las construcciones vecinas, es otro valor positivo que influye favorablemente en el visitante.

  11. Installation of the Ion Accelerator for the Surface Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Hyeok-Jung; Kim, Han-Sung; Chung, Bo-Hyun; Ahn, Tae-Sung; Kim, Dae-Il; Kim, Cho-Rong; Cho, Yong-Sub [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    In this paper, an introduction to the accelerator, an installation status at KOMAC and the operation plan of the accelerator are discussed. A pelletron, which has been used over 25 years at KIGAM, is moved and installed at KOMAC in order to supply a qualified service to ion beam users. The system will be installed in September and component tests will be carried. The operation of the system starts in 2016 after it gets operation license from Nuclear Safety and Security Commission. Korea Multi-purpose Accelerator Complex (KOMAC) is operating several ion beam accelerators to provide various ion beams to users. Those are a 100 MeV proton linear accelerator, a 220 keV ion implanter for gaseous ion beams, a 150 keV metal ion implanter and a 20 keV high-current ion implanter. All of those are the machine for user service and it is important to qualify the results of the irradiation conditions for user service. For this reason, an electrostatic tandem accelerator, which has been operating over 25 years at Korea Institute of Geoscience and Mineral Resources (KIGAM), is moved to KOMAC in order to supply the qualified and quantified data on the irradiation species.

  12. Asia honours accelerator physicists

    CERN Multimedia

    2010-01-01

    "Steve Meyers of Cern and Jie Wei of Beijing's Tsinghua University are the first recipients of a new prize for particle physics. The pair were honoured for their contributions to numerous particle-accelerator projects - including Cern's Large Hadron Collider - by the Asian Committee for Future Accelerators (ACFA)..." (1 paragraph)

  13. COLLECTIVE-FIELD ACCELERATION

    Energy Technology Data Exchange (ETDEWEB)

    Sessler, Andrew M.

    1969-07-04

    Diverse methods proposed for the acceleration of particles by means of collective fields are reviewed. A survey is made of the various currently active experimental programs devoted to investigating collective acceleration, and the present status of the research is briefly noted.

  14. Accelerators Beyond The Tevatron?

    Energy Technology Data Exchange (ETDEWEB)

    Lach, Joseph; /Fermilab

    2010-07-01

    Following the successful operation of the Fermilab superconducting accelerator three new higher energy accelerators were planned. They were the UNK in the Soviet Union, the LHC in Europe, and the SSC in the United States. All were expected to start producing physics about 1995. They did not. Why?

  15. KEK digital accelerator

    Science.gov (United States)

    Iwashita, T.; Adachi, T.; Takayama, K.; Leo, K. W.; Arai, T.; Arakida, Y.; Hashimoto, M.; Kadokura, E.; Kawai, M.; Kawakubo, T.; Kubo, Tomio; Koyama, K.; Nakanishi, H.; Okazaki, K.; Okamura, K.; Someya, H.; Takagi, A.; Tokuchi, A.; Wake, M.

    2011-07-01

    The High Energy Accelerator Research Organization KEK digital accelerator (KEK-DA) is a renovation of the KEK 500 MeV booster proton synchrotron, which was shut down in 2006. The existing 40 MeV drift tube linac and rf cavities have been replaced by an electron cyclotron resonance (ECR) ion source embedded in a 200 kV high-voltage terminal and induction acceleration cells, respectively. A DA is, in principle, capable of accelerating any species of ion in all possible charge states. The KEK-DA is characterized by specific accelerator components such as a permanent magnet X-band ECR ion source, a low-energy transport line, an electrostatic injection kicker, an extraction septum magnet operated in air, combined-function main magnets, and an induction acceleration system. The induction acceleration method, integrating modern pulse power technology and state-of-art digital control, is crucial for the rapid-cycle KEK-DA. The key issues of beam dynamics associated with low-energy injection of heavy ions are beam loss caused by electron capture and stripping as results of the interaction with residual gas molecules and the closed orbit distortion resulting from relatively high remanent fields in the bending magnets. Attractive applications of this accelerator in materials and biological sciences are discussed.

  16. KEK digital accelerator

    Directory of Open Access Journals (Sweden)

    T. Iwashita

    2011-07-01

    Full Text Available The High Energy Accelerator Research Organization KEK digital accelerator (KEK-DA is a renovation of the KEK 500 MeV booster proton synchrotron, which was shut down in 2006. The existing 40 MeV drift tube linac and rf cavities have been replaced by an electron cyclotron resonance (ECR ion source embedded in a 200 kV high-voltage terminal and induction acceleration cells, respectively. A DA is, in principle, capable of accelerating any species of ion in all possible charge states. The KEK-DA is characterized by specific accelerator components such as a permanent magnet X-band ECR ion source, a low-energy transport line, an electrostatic injection kicker, an extraction septum magnet operated in air, combined-function main magnets, and an induction acceleration system. The induction acceleration method, integrating modern pulse power technology and state-of-art digital control, is crucial for the rapid-cycle KEK-DA. The key issues of beam dynamics associated with low-energy injection of heavy ions are beam loss caused by electron capture and stripping as results of the interaction with residual gas molecules and the closed orbit distortion resulting from relatively high remanent fields in the bending magnets. Attractive applications of this accelerator in materials and biological sciences are discussed.

  17. Accelerators, Beams And Physical Review Special Topics - Accelerators And Beams

    Energy Technology Data Exchange (ETDEWEB)

    Siemann, R.H.; /SLAC

    2011-10-24

    Accelerator science and technology have evolved as accelerators became larger and important to a broad range of science. Physical Review Special Topics - Accelerators and Beams was established to serve the accelerator community as a timely, widely circulated, international journal covering the full breadth of accelerators and beams. The history of the journal and the innovations associated with it are reviewed.

  18. The Accelerated Kepler Problem

    CERN Document Server

    Namouni, Fathi

    2007-01-01

    The accelerated Kepler problem is obtained by adding a constant acceleration to the classical two-body Kepler problem. This setting models the dynamics of a jet-sustaining accretion disk and its content of forming planets as the disk loses linear momentum through the asymmetric jet-counterjet system it powers. The dynamics of the accelerated Kepler problem is analyzed using physical as well as parabolic coordinates. The latter naturally separate the problem's Hamiltonian into two unidimensional Hamiltonians. In particular, we identify the origin of the secular resonance in the accelerated Kepler problem and determine analytically the radius of stability boundary of initially circular orbits that are of particular interest to the problem of radial migration in binary systems as well as to the truncation of accretion disks through stellar jet acceleration.

  19. On Accelerated Black Holes

    CERN Document Server

    Letelier, P S; Letelier, Patricio S.; Oliveira, Samuel R.

    1998-01-01

    The C-metric is revisited and global interpretation of some associated spacetimes are studied in some detail. Specially those with two event horizons, one for the black hole and another for the acceleration. We found that the spacetime fo an accelerated Schwarzschild black hole is plagued by either conical singularities or lack of smoothness and compactness of the black hole horizon. By using standard black hole thermodynamics we show that accelerated black holes have higher Hawking temperature than Unruh temperature. We also show that the usual upper bound on the product of the mass and acceleration parameters (<1/sqrt(27)) is just a coordinate artifact. The main results are extended to accelerated Kerr black holes. We found that they are not changed by the black hole rotation.

  20. Flexible and fragmentable tandem photosensitive nanocrystal skins

    Science.gov (United States)

    Akhavan, S.; Uran, C.; Bozok, B.; Gungor, K.; Kelestemur, Y.; Lesnyak, V.; Gaponik, N.; Eychmüller, A.; Demir, H. V.

    2016-02-01

    We proposed and demonstrated the first account of large-area, semi-transparent, tandem photosensitive nanocrystal skins (PNSs) constructed on flexible substrates operating on the principle of photogenerated potential buildup, which avoid the need for applying an external bias and circumvent the current-matching limitation between junctions. We successfully fabricated and operated the tandem PNSs composed of single monolayers of colloidal water-soluble CdTe and CdHgTe nanocrystals (NCs) in adjacent junctions on a Kapton polymer tape. Owing to the usage of a single NC layer in each junction, noise generation was significantly reduced while keeping the resulting PNS films considerably transparent. In each junction, photogenerated excitons are dissociated at the interface of the semi-transparent Al electrode and the NC layer, with holes migrating to the contact electrode and electrons trapped in the NCs. As a result, the tandem PNSs lead to an open-circuit photovoltage buildup equal to the sum of those of the two single junctions, exhibiting a total voltage buildup of 128.4 mV at an excitation intensity of 75.8 μW cm-2 at 350 nm. Furthermore, we showed that these flexible PNSs could be bent over 3.5 mm radius of curvature and cut out in arbitrary shapes without damaging the operation of individual parts and without introducing any significant loss in the total sensitivity. These findings indicate that the NC skins are promising as building blocks to make low-cost, flexible, large-area UV/visible sensing platforms with highly efficient full-spectrum conversion.We proposed and demonstrated the first account of large-area, semi-transparent, tandem photosensitive nanocrystal skins (PNSs) constructed on flexible substrates operating on the principle of photogenerated potential buildup, which avoid the need for applying an external bias and circumvent the current-matching limitation between junctions. We successfully fabricated and operated the tandem PNSs composed of

  1. Tandem robot control system and method for controlling mobile robots in tandem

    Energy Technology Data Exchange (ETDEWEB)

    Hayward, David R. (Albuquerque, NM); Buttz, James H. (Albuquerque, NM); Shirey, David L. (Albuquerque, NM)

    2002-01-01

    A control system for controlling mobile robots provides a way to control mobile robots, connected in tandem with coupling devices, to navigate across difficult terrain or in closed spaces. The mobile robots can be controlled cooperatively as a coupled system in linked mode or controlled individually as separate robots.

  2. Particle acceleration by plasma

    CERN Document Server

    Ogata, A

    2002-01-01

    Plasma acceleration is carried out by using potential of plasma wave. It is classified by generation method of plasma wave such as the laser wake-field acceleration and the beat wave acceleration. Other method using electron beam is named the plasma wake-field acceleration (or beam wake-field acceleration). In this paper, electron acceleration by laser wake-field in gas plasma, ion source by laser radiation of solid target and nanoion beam generation by one component of plasma in trap are explained. It is an applicable method that ions, which run out from the solid target irradiated by laser, are used as ion source of accelerator. The experimental system using 800 nm laser, 50 mJ pulse energy and 50 fs pulse width was studied. The laser intensity is 4x10 sup 1 sup 6 Wcm sup - sup 2 at the focus. The target film of metal and organic substance film was used. When laser irradiated Al target, two particles generated, in front and backward. It is new fact that the neutral particle was obtained in front, because it...

  3. The miniature accelerator

    CERN Multimedia

    Antonella Del Rosso

    2015-01-01

    The image that most people have of CERN is of its enormous accelerators and their capacity to accelerate particles to extremely high energies. But thanks to some cutting-edge studies on beam dynamics and radiofrequency technology, along with innovative construction techniques, teams at CERN have now created the first module of a brand-new accelerator, which will be just 2 metres long. The potential uses of this miniature accelerator will include deployment in hospitals for the production of medical isotopes and the treatment of cancer. It’s a real David-and-Goliath story.   Serge Mathot, in charge of the construction of the "mini-RFQ", pictured with the first of the four modules that will make up the miniature accelerator. The miniature accelerator consists of a radiofrequency quadrupole (RFQ), a component found at the start of all proton accelerator chains around the world, from the smallest to the largest. The LHC is designed to produce very high-intensity beams ...

  4. Cosmic particle acceleration

    Energy Technology Data Exchange (ETDEWEB)

    Zimbardo, Gaetano; Perri, Silvia [Universita della Calabria, Dipartimento di Fisica, 87036 Rende (Italy)

    2014-07-01

    The most popular mechanism for the acceleration of cosmic rays, which is thought to operate in supernova remnant shocks as well as at heliospheric shocks, is the diffusive shock acceleration, which is a Fermi mechanism based on normal diffusion. On the other hand, in the last few years it has been shown that the transport of plasma particles in the presence of electric and magnetic turbulence can be superdiffusive rather than normal diffusive. The term 'superdiffusive' refers to the mean square displacement of particle positions growing superlinearly with time, as compared to the normal linear growth. In particular, superdiffusion is characterized by a non Gaussian statistical process called Levy random walk. We show how diffusive shock acceleration is modified by superdiffusion, and how this yields new predictions for the cosmic ray spectral index, for the acceleration time, and for the spatial profile of energetic particles. A comparison with observations of particle acceleration at heliospheric shocks and at supernova remnant shocks is done. We discuss how superdiffusive shock acceleration allows to explain the observations of hard ion spectra at the solar wind termination shock detected by Voyager 2, of hard radio spectra due to synchrotron emission of electrons accelerated at supernova remnant shocks, and how it can help to explain the observations of 'thin rims' in the X-ray synchrotron emission.

  5. Multicavity proton cyclotron accelerator

    Directory of Open Access Journals (Sweden)

    J. L. Hirshfield

    2002-08-01

    Full Text Available A mechanism for acceleration of protons is described, in which energy gain occurs near cyclotron resonance as protons drift through a sequence of rotating-mode TE_{111} cylindrical cavities in a strong nearly uniform axial magnetic field. Cavity resonance frequencies decrease in sequence from one another with a fixed frequency interval Δf between cavities, so that synchronism can be maintained between the rf fields and proton bunches injected at intervals of 1/Δf. An example is presented in which a 122 mA, 1 MeV proton beam is accelerated to 961 MeV using a cascade of eight cavities in an 8.1 T magnetic field, with the first cavity resonant at 120 MHz and with Δf=8 MHz. Average acceleration gradient exceeds 40 MV/m, average effective shunt impedance is 223 MΩ/m, but maximum surface field in the cavities does not exceed 7.2 MV/m. These features occur because protons make many orbital turns in each cavity and thus experience acceleration from each cavity field many times. Longitudinal and transverse stability appear to be intrinsic properties of the acceleration mechanism, and an example to illustrate this is presented. This acceleration concept could be developed into a proton accelerator for a high-power neutron spallation source, such as that required for transmutation of nuclear waste or driving a subcritical fission burner, provided a number of significant practical issues can be addressed.

  6. A Hybrid Approach To Tandem Cylinder Noise

    Science.gov (United States)

    Lockard, David P.

    2004-01-01

    Aeolian tone generation from tandem cylinders is predicted using a hybrid approach. A standard computational fluid dynamics (CFD) code is used to compute the unsteady flow around the cylinders, and the acoustics are calculated using the acoustic analogy. The CFD code is nominally second order in space and time and includes several turbulence models, but the SST k - omega model is used for most of the calculations. Significant variation is observed between laminar and turbulent cases, and with changes in the turbulence model. A two-dimensional implementation of the Ffowcs Williams-Hawkings (FW-H) equation is used to predict the far-field noise.

  7. Method of fabricating bifacial tandem solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Wojtczuk, Steven J; Chiu, Philip T; Zhang, Xuebing; Gagnon, Edward; Timmons, Michael

    2014-10-07

    A method of fabricating on a semiconductor substrate bifacial tandem solar cells with semiconductor subcells having a lower bandgap than the substrate bandgap on one side of the substrate and with subcells having a higher bandgap than the substrate on the other including, first, growing a lower bandgap subcell on one substrate side that uses only the same periodic table group V material in the dislocation-reducing grading layers and bottom subcells as is present in the substrate and after the initial growth is complete and then flipping the substrate and growing the higher bandgap subcells on the opposite substrate side which can be of different group V material.

  8. Application of Accelerators and Storage Rings: Accelerators in Medicine

    CERN Document Server

    Amaldi, U

    2013-01-01

    This document is part of Subvolume C 'Accelerators and Colliders' of Volume 21 'Elementary Particles' of Landolt-Börnstein - Group I 'Elementary Particles, Nuclei and Atoms'. It contains the the Section '11.3 Accelerators in Medicine' of the Chapter '11 Application of Accelerators and Storage Rings' with the content: 11.3 Accelerators in Medicine 11.3.1 Accelerators and Radiopharmaceuticals 11.3.2 Accelerators and Cancer Therapy

  9. Development of a Compton Camera for Online Range Monitoring of Laser-Accelerated Proton Beams via Prompt-Gamma Detection

    Directory of Open Access Journals (Sweden)

    Thirolf P.G.

    2014-03-01

    Full Text Available Presently large efforts are conducted in Munich towards the development of proton beams for bio-medical applications, generated via the technique of particle acceleration from high-power, short-pulse lasers. While so far mostly offline diagnostics tools are used in this context, we aim at developing a reliable and accurate online range monitoring technique, based on the position-sensitive detection of prompt γ rays emitted from nuclear reactions between the proton beam and the biological sample. For this purpose, we develop a Compton camera, designed to be able to track not only the Compton scattering of the primary photon, but also to detect the secondary Compton electron, thus reducing the Compton cone to an arc segment and by this increasing the source reconstruction efficiency. Design specifications and the status of the protype system are discussed.

  10. Confronting Twin Paradox Acceleration

    Science.gov (United States)

    Murphy, Thomas W.

    2016-05-01

    The resolution to the classic twin paradox in special relativity rests on the asymmetry of acceleration. Yet most students are not exposed to a satisfactory analysis of what exactly happens during the acceleration phase that results in the nonaccelerated observer's more rapid aging. The simple treatment presented here offers both graphical and quantitative solutions to the problem, leading to the correct result that the acceleration-induced age gap is 2Lβ years when the one-way distance L is expressed in light-years and velocity β ≡v/c .

  11. Accelerator mass spectrometry of small biological samples.

    Science.gov (United States)

    Salehpour, Mehran; Forsgard, Niklas; Possnert, Göran

    2008-12-01

    Accelerator mass spectrometry (AMS) is an ultra-sensitive technique for isotopic ratio measurements. In the biomedical field, AMS can be used to measure femtomolar concentrations of labeled drugs in body fluids, with direct applications in early drug development such as Microdosing. Likewise, the regenerative properties of cells which are of fundamental significance in stem-cell research can be determined with an accuracy of a few years by AMS analysis of human DNA. However, AMS nominally requires about 1 mg of carbon per sample which is not always available when dealing with specific body substances such as localized, organ-specific DNA samples. Consequently, it is of analytical interest to develop methods for the routine analysis of small samples in the range of a few tens of microg. We have used a 5 MV Pelletron tandem accelerator to study small biological samples using AMS. Different methods are presented and compared. A (12)C-carrier sample preparation method is described which is potentially more sensitive and less susceptible to contamination than the standard procedures.

  12. A new AMS facility at Inter University Accelerator Centre, New Delhi

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, Pankaj, E-mail: pkb@iuac.res.in [Inter-University Accelerator Center (IUAC), New Delhi (India); Chopra, S. [Inter-University Accelerator Center (IUAC), New Delhi (India); Pattanaik, J.K. [Department of Earth Sciences, Indian Institute of Science Education and Research Kolkata, Nadia, WB (India); Ojha, S.; Gargari, S.; Joshi, R.; Kanjilal, D. [Inter-University Accelerator Center (IUAC), New Delhi (India)

    2015-10-15

    Inter University Accelerator Centre (IUAC), a national facility of government of India, is having a 15UD Pelletron accelerator for multidisciplinary ion beam based research programs. Recently, a new accelerator mass spectrometry (AMS) facility has been developed after incorporating many changes in the existing 15UD Pelletron accelerator. A clean chemistry laboratory for {sup 10}Be and {sup 26}Al with all the modern facilities has also been developed for the chemical processing of samples. {sup 10}Be measurements on sediment samples, inter laboratory comparison results and {sup 26}Al measurements on standard samples are presented in this paper. In addition to the {sup 10}Be and {sup 26}Al AMS facilities, a new {sup 14}C AMS facility based on a dedicated 500 kV tandem ion accelerator with two cesium sputter ion sources, is also being setup at IUAC.

  13. Vibration control in accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Montag, C.

    2011-01-01

    In the vast majority of accelerator applications, ground vibration amplitudes are well below tolerable magnet jitter amplitudes. In these cases, it is necessary and sufficient to design a rigid magnet support structure that does not amplify ground vibration. Since accelerator beam lines are typically installed at an elevation of 1-2m above ground level, special care has to be taken in order to avoid designing a support structure that acts like an inverted pendulum with a low resonance frequency, resulting in untolerable lateral vibration amplitudes of the accelerator components when excited by either ambient ground motion or vibration sources within the accelerator itself, such as cooling water pumps or helium flow in superconducting magnets. In cases where ground motion amplitudes already exceed the required jiter tolerances, for instance in future linear colliders, passive vibration damping or active stabilization may be considered.

  14. Compact particle accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Elizondo-Decanini, Juan M.

    2017-08-29

    A compact particle accelerator having an input portion configured to receive power to produce particles for acceleration, where the input portion includes a switch, is provided. In a general embodiment, a vacuum tube receives particles produced from the input portion at a first end, and a plurality of wafer stacks are positioned serially along the vacuum tube. Each of the plurality of wafer stacks include a dielectric and metal-oxide pair, wherein each of the plurality of wafer stacks further accelerate the particles in the vacuum tube. A beam shaper coupled to a second end of the vacuum tube shapes the particles accelerated by the plurality of wafer stacks into a beam and an output portion outputs the beam.

  15. Rejuvenating CERN's Accelerators

    CERN Multimedia

    2004-01-01

    In the coming years and especially in 2005, CERN's accelerators are going to receive an extensive renovation programme to ensure they will perform reliably and effectively when the LHC comes into service.

  16. Joint International Accelerator School

    CERN Multimedia

    CERN Accelerator School

    2014-01-01

    The CERN and US Particle Accelerator Schools recently organised a Joint International Accelerator School on Beam Loss and Accelerator Protection, held at the Hyatt Regency Hotel, Newport Beach, California, USA from 5-14 November 2014. This Joint School was the 13th in a series of such schools, which started in 1985 and also involves the accelerator communities in Japan and Russia.   Photo courtesy of Alfonse Pham, Michigan State University.   The school attracted 58 participants representing 22 different nationalities, with around half from Europe and the other half from Asia and the Americas. The programme comprised 26 lectures, each of 90 minutes, and 13 hours of case study. The students were given homework each day and had an opportunity to sit a final exam, which counted towards university credit. Feedback from the participants was extremely positive, praising the expertise and enthusiasm of the lecturers, as well as the high standard and quality of their lectures. Initial dis...

  17. Dielectric assist accelerating structure

    Science.gov (United States)

    Satoh, D.; Yoshida, M.; Hayashizaki, N.

    2016-01-01

    A higher-order TM02 n mode accelerating structure is proposed based on a novel concept of dielectric loaded rf cavities. This accelerating structure consists of ultralow-loss dielectric cylinders and disks with irises which are periodically arranged in a metallic enclosure. Unlike conventional dielectric loaded accelerating structures, most of the rf power is stored in the vacuum space near the beam axis, leading to a significant reduction of the wall loss, much lower than that of conventional normal-conducting linac structures. This allows us to realize an extremely high quality factor and a very high shunt impedance at room temperature. A simulation of a 5 cell prototype design with an existing alumina ceramic indicates an unloaded quality factor of the accelerating mode over 120 000 and a shunt impedance exceeding 650 M Ω /m at room temperature.

  18. Measurements of I-129 in meteorites and lunar rock by tandem accelerator mass spectrometry

    Science.gov (United States)

    Nizhiizumi, K.; Arnold, J. R.; Elmore, D.; Gove, H. E.; Honda, M.

    1983-01-01

    Precise measurements of the half-life of I-129 in three different meteorites and one lunar surface rock are reported. The meteorite source of I-129 was produced by cosmic ray secondary neutron reactions on Te, while the source in lunar materials in spallation on barium and rare earth elements. The Abee, Allende, and Dhajala meteorites were examined, together with the lunar rock 14310. Details of the process used to extract the iodine are provided. The Abee and Allende samples exhibited a production of 0.5 atom/min per gm of Te from the (n,2n) reaction and 0.05 atom/min/gm for the (n,gamma) reaction. The I-129 is concluded to be a viable tool for long-lived cosmogenic nuclide studies. Further work to extend the data to include the constancy of the cosmic ray flux, the meteorite bombardment history, and the cosmic exposure age dating by means of the I-129 and Xe-129 method is indicated.

  19. A high energy, heavy ion microprobe for ion beam research on the tandem accelerator at ANSTO

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, D.D.; Siegele, R.; Dytlewski, N.

    1996-04-01

    A comprehensive review is given on the production and use of heavy ion beams with spot sizes of a few {mu}m. The development of a high energy, heavy ion microprobe at ANSTO and its possible applications are discussed. The microprobe is designed to focus a wide range of ion beam types, from light ions such as protons up to ions as heavy as iodine. Details of the ion beam optics, optical calculations and a description of the proposed microbeam design are given. The unique combination of high energy, heavy ions and improved detection systems will provide high sensitivity elemental composition and depth profiling information, allowing surface topography and 3D surface reconstruction to be performed on a broad range of materials. 86 refs., 5 tabs., 15 figs.

  20. Potentiality of the composite fulleren based carbon films as the stripper foils for tandem accelerators

    CERN Document Server

    Vasin, A V; Rusavsky, A V; Totsky, Y I; Vishnevski, I N

    2001-01-01

    The problem of the radiation resistance of the carbon stripper foils is considered. The short review of the experimental data available in literature and original experimental results of the are presented. In the paper discussed is the possibility of composite fulleren based carbon films to be used for preparation of the stripper foils. Some technological methods for preparation of composite fulleren based carbon films are proposed. Raman scattering and atom force microscopy were used for investigation of the fulleren and composite films deposited by evaporation of the C sub 6 sub 0 fulleren powder.

  1. {sup 60}Fe measurements with the PSI/ETH EN tandem accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Gartenmann, P.; Schnabel, C.; Suter, M. [ETHZ, Zurich (Switzerland); Synal, H.A. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1997-09-01

    First AMS measurements of the long-lived radionuclide {sup 60}Fe have been performed. At an energy of 60 MeV, the suppression of the stable isobar {sup 60}Ni is the main difficulty. Spraying hydrogen gas onto the ion source target and extracting the metal single hydrides, the nickel contamination in the beam can be reduced more than 500 fold. In the gas ionization detector another five orders of magnitude of suppression is obtained. A background {sup 60}Fe/Fe ratio of about 10{sup -11} has allowed first measurements with the standard samples used earlier at Argonne National Laboratory. The results of the two facilities are in agreement. (author) 1 fig., 5 refs.

  2. LHCb GPU Acceleration Project

    CERN Document Server

    AUTHOR|(SzGeCERN)744808; Campora Perez, Daniel Hugo; Neufeld, Niko; Vilasis Cardona, Xavier

    2016-01-01

    The LHCb detector is due to be upgraded for processing high-luminosity collisions, which will increase the load on its computation infrastructure from 100 GB/s to 4 TB/s, encouraging us to look for new ways of accelerating the Online reconstruction. The Coprocessor Manager is our new framework for integrating LHCb’s existing computation pipelines with massively parallel algorithms running on GPUs and other accelerators. This paper describes the system and analyzes its performance.

  3. Accelerating News Issue 2

    CERN Document Server

    Kahle, K; Wildner, E

    2012-01-01

    In this summer issue we look at how developments in collimator materials could have applications in aerospace and beyond, and how Polish researchers are harnessing accelerators for medical and industrial uses. We see how the LHC luminosity upgrade is linking with European industry and US researchers, and how the neutrino oscillation community is progressing. We find out the mid-term status of TIARA-PP and how it is mapping European accelerator education resources.

  4. Accelerating Cosmologies from Compactification

    CERN Document Server

    Townsend, P K; Townsend, Paul K.; Wohlfarth, Mattias N.R.

    2003-01-01

    A solution of the (4+n)-dimensional vacuum Einstein equations is found for which spacetime is compactified on a compact hyperbolic manifold of time-varying volume to a flat four-dimensional FLRW cosmology undergoing accelerated expansion in Einstein conformal frame. This shows that the `no-go' theorem forbidding acceleration in `standard' (time-independent) compactifications of string/M-theory does not apply to `cosmological' (time-dependent) hyperbolic compactifications.

  5. Biomedical accelerator mass spectrometry

    Science.gov (United States)

    Freeman, Stewart P. H. T.; Vogel, John S.

    1995-05-01

    Ultrasensitive SIMS with accelerator based spectrometers has recently begun to be applied to biomedical problems. Certain very long-lived radioisotopes of very low natural abundances can be used to trace metabolism at environmental dose levels ( [greater-or-equal, slanted] z mol in mg samples). 14C in particular can be employed to label a myriad of compounds. Competing technologies typically require super environmental doses that can perturb the system under investigation, followed by uncertain extrapolation to the low dose regime. 41Ca and 26Al are also used as elemental tracers. Given the sensitivity of the accelerator method, care must be taken to avoid contamination of the mass spectrometer and the apparatus employed in prior sample handling including chemical separation. This infant field comprises the efforts of a dozen accelerator laboratories. The Center for Accelerator Mass Spectrometry has been particularly active. In addition to collaborating with groups further afield, we are researching the kinematics and binding of genotoxins in-house, and we support innovative uses of our capability in the disciplines of chemistry, pharmacology, nutrition and physiology within the University of California. The field can be expected to grow further given the numerous potential applications and the efforts of several groups and companies to integrate more the accelerator technology into biomedical research programs; the development of miniaturized accelerator systems and ion sources capable of interfacing to conventional HPLC and GMC, etc. apparatus for complementary chemical analysis is anticipated for biomedical laboratories.

  6. Accelerators for America's Future

    Science.gov (United States)

    Bai, Mei

    2016-03-01

    Particle accelerator, a powerful tool to energize beams of charged particles to a desired speed and energy, has been the working horse for investigating the fundamental structure of matter and fundermental laws of nature. Most known examples are the 2-mile long Stanford Linear Accelerator at SLAC, the high energy proton and anti-proton collider Tevatron at FermiLab, and Large Hadron Collider that is currently under operation at CERN. During the less than a century development of accelerator science and technology that led to a dazzling list of discoveries, particle accelerators have also found various applications beyond particle and nuclear physics research, and become an indispensible part of the economy. Today, one can find a particle accelerator at almost every corner of our lives, ranging from the x-ray machine at the airport security to radiation diagnostic and therapy in hospitals. This presentation will give a brief introduction of the applications of this powerful tool in fundermental research as well as in industry. Challenges in accelerator science and technology will also be briefly presented

  7. Turkish population data on the short tandem repeat locus TPOX

    DEFF Research Database (Denmark)

    Vural, B; Poda, M; Atlioglu, E;

    1998-01-01

    Allele and genotype frequencies were determined for the STR (short tandem repeat) locus TPOX in a random Turkish population sample of 200 individuals.......Allele and genotype frequencies were determined for the STR (short tandem repeat) locus TPOX in a random Turkish population sample of 200 individuals....

  8. Negotiating Multiple Identities through eTandem Learning Experiences

    Science.gov (United States)

    Yang, Se Jeong; Yi, Youngjoo

    2017-01-01

    Much of eTandem research has investigated either linguistic or cross-cultural aspects of second language (L2) learning, but relatively little is known about issues of identity construction in an eTandem context. Situating the study within theories and research of language learner identity, we examined ways in which two adult L2 learners (a Korean…

  9. Interpretation of tandem mass spectra of posttranslationally modified peptides

    DEFF Research Database (Denmark)

    Bunkenborg, J.; Matthiesen, R.

    2013-01-01

    Tandem mass spectrometry provides a sensitive means of analyzing the amino acid sequence of peptides and modified peptides by providing accurate mass measurements of precursor and fragment ions. Modern mass spectrometry instrumentation is capable of rapidly generating many thousands of tandem mas...

  10. A solution process for inverted tandem solar cells

    DEFF Research Database (Denmark)

    Larsen-Olsen, Thue Trofod; Bundgaard, Eva; Sylvester-Hvid, Kristian O.

    2011-01-01

    Tandem solar cells with normal and inverted device geometries were prepared by a solution process. Both device types were based on the use of zinc(II)oxide as the electron transporting layer (ETL). The hole transporting layer (HTL) was either PEDOT:PSS for normal geometry tandem solar cells...... or vanadium(V)oxide in the case of inverted tandem cells. It was found that the inverted tandem solar cells performed comparable or better than the normal geometry devices, showing that the connection structure of vanadium(V)oxide, Ag nanoparticles and zinc(II)oxide functions both as a good recombination...... layer, ensuring serial connection, and as a solvent barrier, protecting the first photoactive layer from processing of the second layer. This successfully demonstrates a tandem solar cell fabrication process fully compatible with state-of-the-art solution based automated production procedures....

  11. Diffusive Shock Acceleration and Reconnection Acceleration Processes

    Science.gov (United States)

    Zank, G. P.; Hunana, P.; Mostafavi, P.; Le Roux, J. A.; Li, Gang; Webb, G. M.; Khabarova, O.; Cummings, A.; Stone, E.; Decker, R.

    2015-12-01

    Shock waves, as shown by simulations and observations, can generate high levels of downstream vortical turbulence, including magnetic islands. We consider a combination of diffusive shock acceleration (DSA) and downstream magnetic-island-reconnection-related processes as an energization mechanism for charged particles. Observations of electron and ion distributions downstream of interplanetary shocks and the heliospheric termination shock (HTS) are frequently inconsistent with the predictions of classical DSA. We utilize a recently developed transport theory for charged particles propagating diffusively in a turbulent region filled with contracting and reconnecting plasmoids and small-scale current sheets. Particle energization associated with the anti-reconnection electric field, a consequence of magnetic island merging, and magnetic island contraction, are considered. For the former only, we find that (i) the spectrum is a hard power law in particle speed, and (ii) the downstream solution is constant. For downstream plasmoid contraction only, (i) the accelerated spectrum is a hard power law in particle speed; (ii) the particle intensity for a given energy peaks downstream of the shock, and the distance to the peak location increases with increasing particle energy, and (iii) the particle intensity amplification for a particular particle energy, f(x,c/{c}0)/f(0,c/{c}0), is not 1, as predicted by DSA, but increases with increasing particle energy. The general solution combines both the reconnection-induced electric field and plasmoid contraction. The observed energetic particle intensity profile observed by Voyager 2 downstream of the HTS appears to support a particle acceleration mechanism that combines both DSA and magnetic-island-reconnection-related processes.

  12. New developments in design and applications for Pelletron accelerators

    Indian Academy of Sciences (India)

    Greg Norton

    2002-11-01

    Most of the developments over the last several years related to Pelletron accelerator are in the field of accelerator mass spectrometry (AMS) and other low beam current applications with the exception of a very high DC electron recirculation Pelletron. High precision AMS systems based on tandem Pelletrons from 500 kV to 5 MV terminal potential are now in use for routine high precision AMS measurements. Their performance will be reported. In addition, there has been significant advancement in the design of the multi-cathode SNICS source for the use of both gas and solid samples within a single source. The latest performance of these sources will be discussed. New diagnostics is being developed for very low beam currents. The latest design of the low current beam profile monitor (LCBPM) will also be presented.

  13. Small type accelerator. Try for accelerator driven system

    CERN Document Server

    Mori, Y

    2003-01-01

    FFAG (Fixed-field alternating gradient) accelerator for accelerator driven subcritical reactor, which aims to change from long-lived radioactive waste to short-lived radioactivity, is introduced. It is ring accelerator. The performance needed is proton as accelerator particle, 10MW (total) beam power, about 1GeV beam energy, >30% power efficiency and continuous beam. The feature of FFAG accelerator is constant magnetic field. PoP (Proof-of-principle)-FFAG accelerator, radial type, was run at first in Japan in 2000. The excursion is about some ten cm. In principle, beam can be injected and extracted at any place of ring. The 'multi-fish' acceleration can accelerate beams to 100% duty by repeating acceleration. 150MeV-FFAG accelerator has been started since 2001. It tried to practical use, for example, treatment of cancer. (S.Y.)

  14. Tandem come tirocinio: la riflessione nel corso dell'azione - in un tandem in presenza italiano-portoghese

    Directory of Open Access Journals (Sweden)

    Maria Luisa Vassallo

    2006-04-01

    Full Text Available II presente studio è dedicato al Tandem, un metodo di studio delle lingue straniere autonomo e collaborativo. Esso illustra alcune potenzialità di questa forma didattica per la formazione degli insegnanti, utilizzando il concetto di riflessione nel corso dell'azione elaborato dal filosofo statunitense Donald Schön (1983. Il capitolo 1 introduce il metodo Tandem. Il capitolo 2 analizza il Tandem alla luce della teoria di Schön. Il capitolo 3 descrive l'aspetto riflessivo in un Tandem in presenza, svolto nel 2004 in Brasile. II capitolo 4 propone alcuni motivi per considerare il metodo Tandem un contesto complementare utile per la formazione alla pratica docente attraverso il tirocinio.

  15. Dielectric laser accelerators

    Science.gov (United States)

    England, R. Joel; Noble, Robert J.; Bane, Karl; Dowell, David H.; Ng, Cho-Kuen; Spencer, James E.; Tantawi, Sami; Wu, Ziran; Byer, Robert L.; Peralta, Edgar; Soong, Ken; Chang, Chia-Ming; Montazeri, Behnam; Wolf, Stephen J.; Cowan, Benjamin; Dawson, Jay; Gai, Wei; Hommelhoff, Peter; Huang, Yen-Chieh; Jing, Chunguang; McGuinness, Christopher; Palmer, Robert B.; Naranjo, Brian; Rosenzweig, James; Travish, Gil; Mizrahi, Amit; Schachter, Levi; Sears, Christopher; Werner, Gregory R.; Yoder, Rodney B.

    2014-10-01

    The use of infrared lasers to power optical-scale lithographically fabricated particle accelerators is a developing area of research that has garnered increasing interest in recent years. The physics and technology of this approach is reviewed, which is referred to as dielectric laser acceleration (DLA). In the DLA scheme operating at typical laser pulse lengths of 0.1 to 1 ps, the laser damage fluences for robust dielectric materials correspond to peak surface electric fields in the GV /m regime. The corresponding accelerating field enhancement represents a potential reduction in active length of the accelerator between 1 and 2 orders of magnitude. Power sources for DLA-based accelerators (lasers) are less costly than microwave sources (klystrons) for equivalent average power levels due to wider availability and private sector investment. Because of the high laser-to-particle coupling efficiency, required pulse energies are consistent with tabletop microJoule class lasers. Combined with the very high (MHz) repetition rates these lasers can provide, the DLA approach appears promising for a variety of applications, including future high-energy physics colliders, compact light sources, and portable medical scanners and radiative therapy machines.

  16. Plasma-based accelerator structures

    Energy Technology Data Exchange (ETDEWEB)

    Schroeder, Carl B. [Univ. of California, Berkeley, CA (United States)

    1999-12-01

    Plasma-based accelerators have the ability to sustain extremely large accelerating gradients, with possible high-energy physics applications. This dissertation further develops the theory of plasma-based accelerators by addressing three topics: the performance of a hollow plasma channel as an accelerating structure, the generation of ultrashort electron bunches, and the propagation of laser pulses is underdense plasmas.

  17. Uniform Acceleration in General Relativity

    CERN Document Server

    Friedman, Yaakov

    2016-01-01

    We extend de la Fuente and Romero's defining equation for uniform acceleration in a general curved spacetime from linear acceleration to the full Lorentz covariant uniform acceleration. In a flat spacetime background, we have explicit solutions. We use generalized Fermi-Walker transport to parallel transport the Frenet basis along the trajectory. In flat spacetime, we obtain velocity and acceleration transformations from a uniformly accelerated system to an inertial system. We obtain the time dilation between accelerated clocks. We apply our acceleration transformations to the motion of a charged particle in a constant electromagnetic field and recover the Lorentz-Abraham-Dirac equation.

  18. Cosmic Plasma Wakefield Acceleration

    Energy Technology Data Exchange (ETDEWEB)

    Chen, P

    2004-04-26

    Recently we proposed a new cosmic acceleration mechanism which was based on the wakefields excited by the Alfven shocks in a relativistically owing plasma. In this paper we include some omitted details, and show that there exists a threshold condition for transparency below which the accelerating particle is collision-free and suffers little energy loss in the plasma medium. The stochastic encounters of the random accelerating-decelerating phases results in a power-law energy spectrum: f({epsilon}) {proportional_to} 1/{epsilon}{sup 2}. As an example, we discuss the possible production of super-GZK ultra high energy cosmic rays (UHECR) in the atmosphere of gamma ray bursts. The estimated event rate in our model agrees with that from UHECR observations.

  19. Superconducting Accelerator Magnets

    CERN Document Server

    Mess, K H; Wolff, S

    1996-01-01

    The main topic of the book are the superconducting dipole and quadrupole magnets needed in high-energy accelerators and storage rings for protons, antiprotons or heavy ions. The basic principles of low-temperature superconductivity are outlined with special emphasis on the effects which are relevant for accelerator magnets. Properties and fabrication methods of practical superconductors are described. Analytical methods for field calculation and multipole expansion are presented for coils without and with iron yoke. The effect of yoke saturation and geometric distortions on field quality is studied. Persistent magnetization currents in the superconductor and eddy currents the copper part of the cable are analyzed in detail and their influence on field quality and magnet performance is investigated. Superconductor stability, quench origins and propagation and magnet protection are addressed. Some important concepts of accelerator physics are introduced which are needed to appreciate the demanding requirements ...

  20. Particle accelerator physics

    CERN Document Server

    Wiedemann, Helmut

    2007-01-01

    Particle Accelerator Physics is an in-depth and comprehensive introduction to the field of high-energy particle acceleration and beam dynamics. Part I gathers the basic tools, recalling the essentials of electrostatics and electrodynamics as well as of particle dynamics in electromagnetic fields. Part II is an extensive primer in beam dynamics, followed in Part III by the introduction and description of the main beam parameters. Part IV is devoted to the treatment of perturbations in beam dynamics. Part V discusses the details of charged particle accleration. Part VI and Part VII introduce the more advanced topics of coupled beam dynamics and the description of very intense beams. Part VIII is an exhaustive treatment of radiation from accelerated charges and introduces important sources of coherent radiation such as synchrotrons and free-electron lasers. Part IX collects the appendices gathering useful mathematical and physical formulae, parameters and units. Solutions to many end-of-chapter problems are give...

  1. Studies of accelerated compact toruses

    Energy Technology Data Exchange (ETDEWEB)

    Hartman, C.W.; Eddleman, J.; Hammer, J.H.

    1983-01-04

    In an earlier publication we considered acceleration of plasma rings (Compact Torus). Several possible accelerator configurations were suggested and the possibility of focusing the accelerated rings was discussed. In this paper we consider one scheme, acceleration of a ring between coaxial electrodes by a B/sub theta/ field as in a coaxial rail-gun. If the electrodes are conical, a ring accelerated towards the apex of the cone undergoes self-similar compression (focusing) during acceleration. Because the allowable acceleration force, F/sub a/ = kappaU/sub m//R where (kappa < 1), increases as R/sup -2/, the accelerating distance for conical electrodes is considerably shortened over that required for coaxial electrodes. In either case, however, since the accelerating flux can expand as the ring moves, most of the accelerating field energy can be converted into kinetic energy of the ring leading to high efficiency.

  2. Microelectromechanical acceleration-sensing apparatus

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Robb M. (Albuquerque, NM); Shul, Randy J. (Albuquerque, NM); Polosky, Marc A. (Albuquerque, NM); Hoke, Darren A. (Albuquerque, NM); Vernon, George E. (Rio Rancho, NM)

    2006-12-12

    An acceleration-sensing apparatus is disclosed which includes a moveable shuttle (i.e. a suspended mass) and a latch for capturing and holding the shuttle when an acceleration event is sensed above a predetermined threshold level. The acceleration-sensing apparatus provides a switch closure upon sensing the acceleration event and remains latched in place thereafter. Examples of the acceleration-sensing apparatus are provided which are responsive to an acceleration component in a single direction (i.e. a single-sided device) or to two oppositely-directed acceleration components (i.e. a dual-sided device). A two-stage acceleration-sensing apparatus is also disclosed which can sense two acceleration events separated in time. The acceleration-sensing apparatus of the present invention has applications, for example, in an automotive airbag deployment system.

  3. Sugarcane Tandem Mills Operation at Two Hydraulic Pressure Levels

    Directory of Open Access Journals (Sweden)

    Jorge Michel Corrales-Suárez

    2015-01-01

    Full Text Available Among the areas with more energy consumption in a sugar factory is the tandem of mills. The applied hydraulic pressure on the superior mace is one of the variables that have influence on this energy consumption. Hydraulic pressures were decreased in a value that did not affect the extraction process efficiency to determine the possibilities of decreasing this energy consumption. The research was carried out in two sugar cane tandems of six mills. The pressures were only varied in the extraction mills in humid according to a statistical design of experiments in random blocks. The results were analyzed by means of the analysis of variance of double classification. The independent variables were the hydraulic pressures in the intermediate mills while the dependent variables were the % pol and % humidity of the final bagasse. The hydraulic pressures of the intermediate mills were reduced 3.45 MPa in the Tandem 1 and 2.07 MPa in the Tandem 2. It was demonstrated that under the conditions of the experiment, the employment of working hydraulic pressures smaller than the usually established ones for each tandem did not affect the extraction process of the sugar cane sucrose significantly, but decreased 11.75% the power demand on tandem 1 and 8.17% on tandem 2.

  4. Accelerating time to benefit

    DEFF Research Database (Denmark)

    Svejvig, Per; Geraldi, Joana; Grex, Sara

    Despite the ubiquitous pressure for speed, our approaches to accelerate projects remain constrained to the old-fashioned understanding of the project as a vehicle to deliver products and services, not value. This article explores an attempt to accelerate time to benefit. We describe and deconstruct...... of the time. Although all cases valued speed and speed to benefit, and implemented most practices proposed by the methodology, only three of the five projects were more successful in decreasing time to speed. Based on a multi-case study comparison between these five different projects and their respective...

  5. Accelerating News Issue 4

    CERN Document Server

    Szeberenyi, A; Wildner, E

    2012-01-01

    In this winter issue, we are very pleased to announce the approval of EuCARD-2 by the European Commission. We look at the conclusions of EUROnu in proposing future neutrino facilities at CERN, a new milestone reached by CLIC and progress on the SPARC upgrade using C-band technology. We also report on recent events: second Joint HiLumi LHC-LARP Annual Meeting and workshop on Superconducting technologies for the Next Generation of Accelerators aiming at closer collaboration with industry. The launch of the Accelerators for Society brochure is also highlighted.

  6. Shielding high energy accelerators

    CERN Document Server

    Stevenson, Graham Roger

    2001-01-01

    After introducing the subject of shielding high energy accelerators, point source, line-of-sight models, and in particular the Moyer model. are discussed. Their use in the shielding of proton and electron accelerators is demonstrated and their limitations noted. especially in relation to shielding in the forward direction provided by large, flat walls. The limitations of reducing problems to those using it cylindrical geometry description are stressed. Finally the use of different estimators for predicting dose is discussed. It is suggested that dose calculated from track-length estimators will generally give the most satisfactory estimate. (9 refs).

  7. Characterization of a solid deuterium converter for ultra-cold neutrons (UCN) in the framework of the Mini-D{sub 2} project at the FRM-II reactor in Munich

    Energy Technology Data Exchange (ETDEWEB)

    Tortorella, D.

    2007-02-07

    Spontaneous breaking of fundamental symmetries is an attractive topic in modern particles physic. Understanding qualitative and quantitative the parameters involved in these kind of processes could help to explain the unbalanced presence in the universe of matter (baryons) with respect to antimatter (anti-baryons). Due to their intrinsic properties, ultra cold neutrons (UCN) are excellent candidates in experiments measuring with high level of accuracy parameters like the electric dipole moment (EDM), the axial-vector coupling constant (g{sub A}), the neutron lifetime ({tau}{sub n}) or in search of quantum effect of gravity. In this work are presented several contributions in the framework of the Mini-D2 project, an innovative strong UCN source under construction at the FRM-II reactor in Munich. An important component of this facility, the solid deuterium UCN converter, is one subject of the thesis. (orig.)

  8. Numerical evaluation of tandem rotor for highly loaded transonic fan

    Institute of Scientific and Technical Information of China (English)

    ZHAO Bin; LIU Bao-jie

    2011-01-01

    Transonic tandem rotor was designed for highly loaded fan at a corrected tip speed of 381 m/s and another conventional rotor was designed as a baseline to evaluate the loading superiority of tandem rotor with three-dimensional (3-D) numerical simulation. The aft blade solidity and its impact on total loading level were studied in depth. The result indicates that tandem rotor has potential to achieve higher loading level and attain favorable aerodynamic performance in a wide range of loading coefficient 0. 55 ~ 0.68, comparing with the conventional rotor which produced a total pressure ratio of 2.0 and loading coefficient of 0. 42.

  9. Querschnittevaluation des Medizinischen Curriculums München (MeCuM mit Hilfe des Progress Tests Medizin (PTM [Using the Progress Test Medizin (PTM for evaluation of the Medical Curriculum Munich (MeCuM

    Directory of Open Access Journals (Sweden)

    Reincke, Martin

    2010-11-01

    Full Text Available [english] Aims: The Medical Curriculum Munich (MeCuM has been implemented since 2004 and was completely established in 2007. In this study the clinical part of MeCuM was evaluated with respect to retention of the knowledge in internal medicine (learning objectives of the 6th/7th semester. Methods: In summer of 2009 and winter of 2009/2010 1065 students participated in the Progress Test Medizin (PTM from Charité Medical School Berlin. Additionally the students answered a questionnaire regarding the acceptance and rating of the progress test and basic demographic data. Results: The knowledge of internal medicine continuously increases during the clinical part of the medical curriculum in Munich. However, significant differences between the sub-disciplines of internal medicine could be observed. The overall acceptance of the PTM was high and increased further with the study progress. Interestingly, practical experiences like clinical clerkships positively influenced the test score. Conclusions: The PTM is a useful tool for the evaluation of knowledge retention in a specific curriculum. [german] Zielsetzung: Das Medizinische Curriculum München (MeCuM wurde seit 2004 implementiert. Seit 2007 ist MeCuM im klinischen Studienabschnitt voll etabliert (Ende der Übergangsregelungen. Aktuell sollte MeCuM bezüglich der Nachhaltigkeit des im Modul 2 „Konservative Medizin“ (6./7. Semester vermittelten Wissens evaluiert werden.Methodik: Im Sommersemester 2009 und Wintersemester 2009/2010 absolvierten 1065 Studierende den Progress Test Medizin (PTM. Zusätzlich beantworteten die Studierenden einen Fragebogen zur Akzeptanz und Bewertung des PTM sowie zu demographischen Basisdaten.Ergebnisse: Das Wissen „Konservative Medizin“ nimmt im klinischen Studienabschnitt kontinuierlich zu, wobei sich deutliche Unterschiede in den internistischen Subdisziplinen zeigen. Die Akzeptanz des PTM ist sehr hoch und nimmt im Studienverlauf zu. Praktische Erfahrungen

  10. Combined generating-accelerating buncher for compact linear accelerators

    Science.gov (United States)

    Savin, E. A.; Matsievskiy, S. V.; Sobenin, N. P.; Sokolov, I. D.; Zavadtsev, A. A.

    2016-09-01

    Described in the previous article [1] method of the power extraction from the modulated electron beam has been applied to the compact standing wave electron linear accelerator feeding system, which doesnt require any connection waveguides between the power source and the accelerator itself [2]. Generating and accelerating bunches meet in the hybrid accelerating cell operating at TM020 mode, thus the accelerating module is placed on the axis of the generating module, which consists from the pulsed high voltage electron sources and electrons dumps. This combination makes the accelerator very compact in size which is very valuable for the modern applications such as portable inspection sources. Simulations and geometry cold tests are presented.

  11. The CERN accelerator complex

    CERN Multimedia

    Christiane Lefèvre

    2008-01-01

    The LHC is the last ring (dark grey line) in a complex chain of particle accelerators. The smaller machines are used in a chain to help boost the particles to their final energies and provide beams to a whole set of smaller experiments, which also aim to uncover the mysteries of the Universe.

  12. The CERN Accelerator School

    CERN Multimedia

    2016-01-01

      Introduction to accelerator physics This course will take place in Istanbul, Turkey, from 18 to 30 September 2016. It is now open for registration, and further information can be found here: http://cas.web.cern.ch/cas/Turkey-2016/Turkey-advert.html

  13. The CERN Accelerator School

    CERN Multimedia

    2016-01-01

    Introduction to accelerator physics This course will take place in Budapest, Hungary, from 2 to 14 October 2016. It is now open for registration and further information can be found at: http://cas.web.cern.ch/cas/Hungary2016/Hungary-advert.html and http://indico.cern.ch/event/532397/.

  14. The CERN accelerator complex

    CERN Multimedia

    De Melis, Cinzia

    2016-01-01

    The LHC is the last ring (dark blue line) in a complex chain of particle accelerators. The smaller machines are used in a chain to help boost the particles to their final energies and provide beams to a whole set of smaller experiments, which also aim to uncover the mysteries of the Universe.

  15. Acceleration and Special Relativity

    CERN Document Server

    Yahalomi, E M

    2000-01-01

    The integration of acceleration over time before reaching the uniformvelocity turns out to be the source of all the special relativity effects. Itexplains physical phenomena like clocks comparisons. The equations forspace-time, mass and energy are presented. This phenomenon complements theexplanation for the twins paradox. A Universal reference frame is obtained.

  16. Prospects for Accelerator Technology

    Science.gov (United States)

    Todd, Alan

    2011-02-01

    Accelerator technology today is a greater than US$5 billion per annum business. Development of higher-performance technology with improved reliability that delivers reduced system size and life cycle cost is expected to significantly increase the total accelerator technology market and open up new application sales. Potential future directions are identified and pitfalls in new market penetration are considered. Both of the present big market segments, medical radiation therapy units and semiconductor ion implanters, are approaching the "maturity" phase of their product cycles, where incremental development rather than paradigm shifts is the norm, but they should continue to dominate commercial sales for some time. It is anticipated that large discovery-science accelerators will continue to provide a specialty market beset by the unpredictable cycles resulting from the scale of the projects themselves, coupled with external political and economic drivers. Although fraught with differing market entry difficulties, the security and environmental markets, together with new, as yet unrealized, industrial material processing applications, are expected to provide the bulk of future commercial accelerator technology growth.

  17. The CERN accelerator complex

    CERN Multimedia

    Haffner, Julie

    2013-01-01

    The LHC is the last ring (dark grey line) in a complex chain of particle accelerators. The smaller machines are used in a chain to help boost the particles to their final energies and provide beams to a whole set of smaller experiments, which also aim to uncover the mysteries of the Universe.

  18. SPS accelerating cavity

    CERN Multimedia

    1980-01-01

    One of the SPS acceleration cavities (200 MHz, travelling wave structure). On the ceiling one sees the coaxial transmission line which feeds the power from the amplifier, located in a surface building above, to the upstream end of the cavity. See 7603195 for more details, 7411032 for the travelling wave structure, and also 8104138, 8302397.

  19. The CERN accelerator complex

    CERN Multimedia

    Mobs, Esma Anais

    2016-01-01

    The LHC is the last ring (dark blue line) in a complex chain of particle accelerators. The smaller machines are used in a chain to help boost the particles to their final energies and provide beams to a whole set of smaller experiments, which also aim to uncover the mysteries of the Universe.

  20. Atmospheric and accelerator neutrinos

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Yoichiro [Kamioka Observatory, Institute for Cosmic Ray Research, University of Tokyo Higashi-Mozumi, Kamioka, Hida-City, Gifu 506-1205 (Japan)

    2006-05-15

    Results from the atmospheric neutrino measurements are presented. Evidence for the {nu}{sub {tau}} appearance in the atmospheric neutrino events was shown by statistical methods. The long baseline oscillation experiment using man-made neutrinos has confirmed the atmospheric neutrino oscillation. The future accelerator experiments are briefly discussed.

  1. SPS accelerating cavity

    CERN Multimedia

    CERN PhotoLab

    1981-01-01

    One of the SPS accelerating cavities (200 MHz, travelling wave structure). The power that is fed into the upstream end of the cavity is extracted at the downstream end and sent into a dump load. See 7603195 for more details, 7411032 for the travelling wave structure, and also 8011289, 8302397.

  2. Angular Accelerating White Light

    CSIR Research Space (South Africa)

    Dudley, Angela L

    2015-08-01

    Full Text Available Shaping XVI, 958104, San Diego, California, United States, 09 August 2015 Angular Accelerating White Light Angela Dudley*a,b, Christian Vetterc , Alexander Szameitc , and Andrew Forbesa,b a CSIR National Laser Centre, PO Box 395, Pretoria 0001...

  3. Neurodegeneration in accelerated aging.

    Science.gov (United States)

    Scheibye-Knudsen, Moren

    2016-11-01

    The growing proportion of elderly people represents an increasing economic burden, not least because of age-associated diseases that pose a significant cost to the health service. Finding possible interventions to age-associated disorders therefore have wide ranging implications. A number of genetically defined accelerated aging diseases have been characterized that can aid in our understanding of aging. Interestingly, all these diseases are associated with defects in the maintenance of our genome. A subset of these disorders, Cockayne syndrome, Xeroderma pigmentosum group A and ataxia-telangiectasia, show neurological involvement reminiscent of what is seen in primary human mitochondrial diseases. Mitochondria are the power plants of the cells converting energy stored in oxygen, sugar, fat, and protein into ATP, the energetic currency of our body. Emerging evidence has linked this organelle to aging and finding mitochondrial dysfunction in accelerated aging disorders thereby strengthens the mitochondrial theory of aging. This theory states that an accumulation of damage to the mitochondria may underlie the process of aging. Indeed, it appears that some accelerated aging disorders that show neurodegeneration also have mitochondrial dysfunction. The mitochondrial alterations may be secondary to defects in nuclear DNA repair. Indeed, nuclear DNA damage may lead to increased energy consumption, alterations in mitochondrial ATP production and defects in mitochondrial recycling, a term called mitophagy. These changes may be caused by activation of poly-ADP-ribose-polymerase 1 (PARP1), an enzyme that responds to DNA damage. Upon activation PARP1 utilizes key metabolites that attenuate pathways that are normally protective for the cell. Notably, pharmacological inhibition of PARP1 or reconstitution of the metabolites rescues the changes caused by PARP1 hyperactivation and in many cases reverse the phenotypes associated with accelerated aging. This implies that modulation

  4. The accelerator neutron source for boron neutron capture therapy

    Science.gov (United States)

    Kasatov, D.; Koshkarev, A.; Kuznetsov, A.; Makarov, A.; Ostreinov, Yu; Shchudlo, I.; Sorokin, I.; Sycheva, T.; Taskaev, S.; Zaidi, L.

    2016-11-01

    The accelerator based epithermal neutron source for Boron Neutron Capture Therapy (BNCT) is proposed, created and used in the Budker Institute of Nuclear Physics. In 2014, with the support of the Russian Science Foundation created the BNCT laboratory for the purpose to the end of 2016 get the neutron flux, suitable for BNCT. For getting 3 mA 2.3 MeV proton beam, was created a new type accelerator - tandem accelerator with vacuum isolation. On this moment, we have a stationary proton beam with 2.3 MeV and current 1.75 mA. Generation of neutrons is carried out by dropping proton beam on to lithium target as a result of threshold reaction 7Li(p,n)7Be. Established facility is a unique scientific installation. It provides a generating of neutron flux, including a monochromatic energy neutrons, gamma radiation, alpha-particles and positrons, and may be used by other research groups for carrying out scientific researches. The article describes an accelerator neutron source, presents and discusses the result of experiments and declares future plans.

  5. Monolithic Perovskite Silicon Tandem Solar Cells with Advanced Optics

    Energy Technology Data Exchange (ETDEWEB)

    Goldschmidt, Jan C.; Bett, Alexander J.; Bivour, Martin; Blasi, Benedikt; Eisenlohr, Johannes; Kohlstadt, Markus; Lee, Seunghun; Mastroianni, Simone; Mundt, Laura; Mundus, Markus; Ndione, Paul; Reichel, Christian; Schubert, Martin; Schulze, Patricia S.; Tucher, Nico; Veit, Clemens; Veurman, Welmoed; Wienands, Karl; Winkler, Kristina; Wurfel, Uli; Glunz, Stefan W.; Hermle, Martin

    2016-11-14

    For high efficiency monolithic perovskite silicon tandem solar cells, we develop low-temperature processes for the perovskite top cell, rear-side light trapping, optimized perovskite growth, transparent contacts and adapted characterization methods.

  6. Light management of tandem solar cells on nanostructured substrates

    Science.gov (United States)

    Chin, Alan H.; Keshavarz, Majid; Wang, Guo; Yu, Rosaline; Niu, Xinwei; Yang, Liyou

    2017-04-01

    We report the use of nanostructured substrates as a simple approach to improve the performance of tandem micromorph silicon solar cells. In the proposed approach, nanostructured substrates are produced using a low-cost, self-assembled growth process. The use of a nanostructured substrate coated with a thick transparent conductive oxide electrode layer enables the conformal deposition of the tandem solar cell absorber layers while allowing the solar cell to exhibit a modified surface morphology caused by the underlying nanostructured morphology. Using this nanostructured substrate approach, we demonstrated a 78% relative enhancement in the conversion efficiency of a tandem micromorph silicon cell on a nanostructured substrate compared to a standard tandem micromorph cell deposited onto a flat substrate.

  7. Detailed balance limit of the efficiency of tandem solar cells

    Science.gov (United States)

    de Vos, A.

    1980-05-01

    The fundamental (detailed balance) limit of the performance of a tandem structure is presented. The model takes into account the fact that a particular cell is not only illuminated by part of the solar irradiance but also by the electroluminescence of other cells of the set. Whereas under 1 sun irradiance a single solar cell only converts 30% of the solar energy, a tandem structure of two cells can convert 42%, a tandem structure of three cells can convert 49%, etc. Under the highest possible light concentration, these efficiencies are 40% (one cell), 55% (two cells), 63% (three cells), etc. The model also allows one to predict the ideal efficiency of a stack with an infinite number of solar cells. Such a tandem system can convert 68% of the unconcentrated sunlight, and 86% of the concentrated sunlight.

  8. Solar-to-Chemical Energy Conversion with Photoelectrochemical Tandem Cells.

    Science.gov (United States)

    Sivula, Kevin

    2013-01-01

    Efficiently and inexpensively converting solar energy into chemical fuels is an important goal towards a sustainable energy economy. An integrated tandem cell approach could reasonably convert over 20% of the sun's energy directly into chemical fuels like H2 via water splitting. Many different systems have been investigated using various combinations of photovoltaic cells and photoelectrodes, but in order to be economically competitive with the production of H2 from fossil fuels, a practical water splitting tandem cell must optimize cost, longevity and performance. In this short review, the practical aspects of solar fuel production are considered from the perspective of a semiconductor-based tandem cell and the latest advances with a very promising technology - metal oxide photoelectrochemical tandem cells - are presented.

  9. Zinc Mediated Tandem Fragmentation-Allylation of Methyl 5-Iodopentofuranosides

    DEFF Research Database (Denmark)

    Hyldtoft, Lene; Madsen, Robert

    1999-01-01

    In the presence of zinc and allyl bromide methyl 5-iodopentofuranosides undergo a tandem fragmentation alkylation to give functionalized dienes. These can undergo ring-closing olefin metathesis to produce cyclohexenes which on dihydroxylation give quercitols....

  10. SYMTRAN - A Time-dependent Symmetric Tandem Mirror Transport Code

    Energy Technology Data Exchange (ETDEWEB)

    Hua, D; Fowler, T

    2004-06-15

    A time-dependent version of the steady-state radial transport model in symmetric tandem mirrors in Ref. [1] has been coded up and first tests performed. Our code, named SYMTRAN, is an adaptation of the earlier SPHERE code for spheromaks, now modified for tandem mirror physics. Motivated by Post's new concept of kinetic stabilization of symmetric mirrors, it is an extension of the earlier TAMRAC rate-equation code omitting radial transport [2], which successfully accounted for experimental results in TMX. The SYMTRAN code differs from the earlier tandem mirror radial transport code TMT in that our code is focused on axisymmetric tandem mirrors and classical diffusion, whereas TMT emphasized non-ambipolar transport in TMX and MFTF-B due to yin-yang plugs and non-symmetric transitions between the plugs and axisymmetric center cell. Both codes exhibit interesting but different non-linear behavior.

  11. Nonlinear dynamics in particle accelerators

    CERN Document Server

    Dilão, Rui

    1996-01-01

    This book is an introductory course to accelerator physics at the level of graduate students. It has been written for a large audience which includes users of accelerator facilities, accelerator physicists and engineers, and undergraduates aiming to learn the basic principles of construction, operation and applications of accelerators.The new concepts of dynamical systems developed in the last twenty years give the theoretical setting to analyse the stability of particle beams in accelerator. In this book a common language to both accelerator physics and dynamical systems is integrated and dev

  12. Solution-Processed Nanocrystal Quantum Dot Tandem Solar Cells

    KAUST Repository

    Choi, Joshua J.

    2011-06-03

    Solution-processed tandem solar cells created from nanocrystal quantum dots with size-tuned energy levels are demonstrated. Prototype devices featuring interconnected quantum dot layers of cascaded energy gaps exhibit IR sensitivity and an open circuit voltage, V oc, approaching 1 V. The tandem solar cell performance depends critically on the optical and electrical properties of the interlayer. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Zinc Mediated Tandem Fragmentation-Allylation of Methyl 5-Iodopentofuranosides

    DEFF Research Database (Denmark)

    Hyldtoft, Lene; Madsen, Robert

    1999-01-01

    In the presence of zinc and allyl bromide methyl 5-iodopentofuranosides undergo a tandem fragmentation alkylation to give functionalized dienes. These can undergo ring-closing olefin metathesis to produce cyclohexenes which on dihydroxylation give quercitols.......In the presence of zinc and allyl bromide methyl 5-iodopentofuranosides undergo a tandem fragmentation alkylation to give functionalized dienes. These can undergo ring-closing olefin metathesis to produce cyclohexenes which on dihydroxylation give quercitols....

  14. Solution-processed nanocrystal quantum dot tandem solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Joshua J.; Lim, Yee-Fun [School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853 (United States); Wenger, Whitney N.; Hoffman, Rachel S.; Hanrath, Tobias [School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853 (United States); Luria, Justin; Marohn, John A. [Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853 (United States); Jasieniak, Jacek [CSIRO Materials Science and Engineering, Bayview Ave, Clayton, Victoria 3168 (Australia)

    2011-07-26

    Solution-processed tandem solar cells created from nanocrystal quantum dots with size-tuned energy levels are demonstrated. Prototype devices featuring interconnected quantum dot layers of cascaded energy gaps exhibit IR sensitivity and an open circuit voltage, V{sub oc}, approaching 1 V. The tandem solar cell performance depends critically on the optical and electrical properties of the interlayer. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  15. Intragenic tandem repeat variation between Legionella pneumophila strains

    Directory of Open Access Journals (Sweden)

    Jarraud Sophie

    2008-12-01

    Full Text Available Abstract Background Bacterial genomes harbour a large number of tandem repeats, yet the possible phenotypic effects of those found within the coding region of genes are only beginning to be examined. Evidence exists from other organisms that these repeats can be involved in the evolution of new genes, gene regulation, adaptation, resistance to environmental stresses, and avoidance of the immune system. Results In this study, we have investigated the presence and variability in copy number of intragenic tandemly repeated sequences in the genome of Legionella pneumophila, the etiological agent of a severe pneumonia known as Legionnaires' disease. Within the genome of the Philadelphia strain, we have identified 26 intragenic tandem repeat sequences using conservative selection criteria. Of these, seven were "polymorphic" in terms of repeat copy number between a large number of L. pneumophila serogroup 1 strains. These strains were collected from a wide variety of environments and patients in several geographical regions. Within this panel of strains, all but one of these seven genes exhibited statistically different patterns in repeat copy number between samples from different origins (environmental, clinical, and hot springs. Conclusion These results support the hypothesis that intragenic tandem repeats could play a role in virulence and adaptation to different environments. While tandem repeats are an increasingly popular focus of molecular typing studies in prokaryotes, including in L. pneumophila, this study is the first examining the difference in tandem repeat distribution as a function of clinical or environmental origin.

  16. Traditional and modern medicine working in tandem

    Directory of Open Access Journals (Sweden)

    E. Pretorius

    1991-09-01

    Full Text Available Because of the many problem relating to health care delivery in Africa, it is becoming apparent that neither the exclusive/monopolistic nor the tolerant legislative systems should be tolerated any longer. Especially since the Alma Ata Conference held by the WHO/UNICEF there has been growing impetus towards either inclusive/parallel (the beneficial co-existence of traditional and modern medical systems, or integrated systems. Although the idea of making traditional and modern medicine work in tandem in a united treatment context has its merits, it is also plagued by issues such as the nature of the products of an integrated training, resistance by stubborn protagonists of either of the two systems, or that only lip-service is paid to the idea of co-operation. Nevertheless, it is believed that all interest groups - the authorities responsible for health care delivery, the Western-trained health care workers, the traditional healers and the users of these services - stand to gain from such liaison.

  17. Wake-induced vibrations in Tandem Cylinders

    Science.gov (United States)

    Mysa, Ravi Chaithanya; Jaiman, Rajeev Kumar

    2015-11-01

    The upstream cylinder is fixed in the tandem cylinders arrangement. The downstream cylinder is placed at a distance of four diameters from the upstream cylinder in the free stream direction and is mounted on a spring. The dynamic response of the downstream cylinder is studied at Reynolds number of 10,000. The transverse displacement amplitude of the downstream cylinder is larger compared to that of single cylinder in the post-lock-in region. The transverse dynamic response of the downstream cylinder in the post-lock-in region is characterized by a dominant low frequency component compared to shed frequency, which is nearer to the structural natural frequency. The interaction of upstream wake with the downstream cylinder is carefully analyzed to understand the introduction of low frequency component in the transverse load along with the shed frequency. We found that the stagnation point moves in proportional to the velocity of the cylinder and is in-phase with the velocity. The low frequency component in the stagnation point movement on the downstream cylinder is sustained by the interaction of upstream wake. The frequencies in the movement of the stagnation point is reflected in the transverse load resulting in large deformation of the cylinder. The authors wish to acknowledge support from A*STAR- SERC and Singapore Maritime Institute.

  18. Tandem mass spectrometry: analysis of complex mixtures

    Energy Technology Data Exchange (ETDEWEB)

    Singleton, K.E.

    1985-01-01

    Applications of tandem mass spectrometry (MS/MS) for the analysis of complex mixtures results in increased specificity and selectivity by using a variety of reagent gases in both negative and positive ion modes. Natural isotopic abundance ratios were examined in both simple and complex mixtures using parent, daughter and neutral loss scans. MS/MS was also used to discover new compounds. Daughter scans were used to identify seven new alkaloids in a cactus species. Three of these alkaloids were novel compounds, and included the first simple, fully aromatic isoquinoline alkaloids reported in Cactaceae. MS/MS was used to characterize the chemical reaction products of coal in studies designed to probe its macromolecular structure. Negative ion chemical ionization was utilized to study reaction products resulting from the oxidation of coal. Possible structural units in the precursor coal were predicted based on the reaction products identified, aliphatic and aromatic acids and their anhydrides. The MS/MS method was also used to characterize reaction products resulting from coal liquefaction and/or extraction. These studies illustrate the types of problems for which MS/MS is useful. Emphasis has been placed on characterization of complex mixtures by selecting experimental parameters which enhance the information obtained. The value of using MS/MS in conjunction with other analytical techniques as well as the chemical pretreatment is demonstrated.

  19. Acceleration of microparticle

    CERN Document Server

    Shibata, H

    2002-01-01

    A microparticle (dust) ion source has been installed at the high voltage terminal of the 3.75 MV single ended Van de Graaff electrostatic accelerator and a beam line for microparticle experiments has been build at High Fluence Irradiation Facility (HIT) of Research Center for Nuclear Science and Technology, the University of Tokyo. Microparticle acceleration has been successful in obtaining expected velocities of 1-20 km/s or more for micron or submicron sized particles. Development of in situ dust detectors and analyzers on board satellites and spacecraft in the expected mass and velocity range of micrometeoroids and investigation of hypervelocity impact phenomena by using time of flight mass spectrometry, impact flash or luminescence measurement and scanning electron or laser microscope observation for metals, ceramics, polymers and semiconductors bombarded by micron-sized particles were started three years ago. (author)

  20. Accelerated Parallel Texture Optimization

    Institute of Scientific and Technical Information of China (English)

    Hao-Da Huang; Xin Tong; Wen-Cheng Wang

    2007-01-01

    Texture optimization is a texture synthesis method that can efficiently reproduce various features of exemplar textures. However, its slow synthesis speed limits its usage in many interactive or real time applications. In this paper, we propose a parallel texture optimization algorithm to run on GPUs. In our algorithm, k-coherence search and principle component analysis (PCA) are used for hardware acceleration, and two acceleration techniques are further developed to speed up our GPU-based texture optimization. With a reasonable precomputation cost, the online synthesis speed of our algorithm is 4000+ times faster than that of the original texture optimization algorithm and thus our algorithm is capable of interactive applications. The advantages of the new scheme are demonstrated by applying it to interactive editing of flow-guided synthesis.

  1. accelerating cavity from LEP

    CERN Multimedia

    This is an accelerating cavity from LEP, with a layer of niobium on the inside. Operating at 4.2 degrees above absolute zero, the niobium is superconducting and carries an accelerating field of 6 million volts per metre with negligible losses. Each cavity has a surface of 6 m2. The niobium layer is only 1.2 microns thick, ten times thinner than a hair. Such a large area had never been coated to such a high accuracy. A speck of dust could ruin the performance of the whole cavity so the work had to be done in an extremely clean environment. These challenging requirements pushed European industry to new achievements. 256 of these cavities are now used in LEP to double the energy of the particle beams.

  2. Particle accelerator physics

    CERN Document Server

    Wiedemann, Helmut

    2015-01-01

    This book by Helmut Wiedemann is a well-established, classic text, providing an in-depth and comprehensive introduction to the field of high-energy particle acceleration and beam dynamics. The present 4th edition has been significantly revised, updated and expanded. The newly conceived Part I is an elementary introduction to the subject matter for undergraduate students. Part II gathers the basic tools in preparation of a more advanced treatment, summarizing the essentials of electrostatics and electrodynamics as well as of particle dynamics in electromagnetic fields. Part III is an extensive primer in beam dynamics, followed, in Part IV, by an introduction and description of the main beam parameters and including a new chapter on beam emittance and lattice design. Part V is devoted to the treatment of perturbations in beam dynamics. Part VI then discusses the details of charged particle acceleration. Parts VII and VIII introduce the more advanced topics of coupled beam dynamics and describe very intense bea...

  3. SUPERDIFFUSIVE SHOCK ACCELERATION

    Energy Technology Data Exchange (ETDEWEB)

    Perri, S.; Zimbardo, G. [Dipartimento di Fisica, Universita della Calabria, Ponte P. Bucci Cubo 31C, I-87036 Rende (Italy)

    2012-05-10

    The theory of diffusive shock acceleration is extended to the case of superdiffusive transport, i.e., when the mean square deviation grows proportionally to t{sup {alpha}}, with {alpha} > 1. Superdiffusion can be described by a statistical process called Levy random walk, in which the propagator is not a Gaussian but it exhibits power-law tails. By using the propagator appropriate for Levy random walk, it is found that the indices of energy spectra of particles are harder than those obtained where a normal diffusion is envisaged, with the spectral index decreasing with the increase of {alpha}. A new scaling for the acceleration time is also found, allowing substantially shorter times than in the case of normal diffusion. Within this framework we can explain a number of observations of flat spectra in various astrophysical and heliospheric contexts, for instance, for the Crab Nebula and the termination shock of the solar wind.

  4. Accelerating time to benefit

    DEFF Research Database (Denmark)

    Svejvig, Per; Geraldi, Joana; Grex, Sara

    Despite the ubiquitous pressure for speed, our approaches to accelerate projects remain constrained to the old-fashioned understanding of the project as a vehicle to deliver products and services, not value. This article explores an attempt to accelerate time to benefit. We describe and deconstruct...... the implementation of a large intervention undertaken in five project-based organizations in Denmark – the Project Half Double where the same project methodology has been applied in five projects, each of them in five distinct organizations in Denmark, as a bold attempt to realize double the benefit in half...... of the time. Although all cases valued speed and speed to benefit, and implemented most practices proposed by the methodology, only three of the five projects were more successful in decreasing time to speed. Based on a multi-case study comparison between these five different projects and their respective...

  5. Accelerating QDP++ using GPUs

    CERN Document Server

    Winter, Frank

    2011-01-01

    Graphic Processing Units (GPUs) are getting increasingly important as target architectures in scientific High Performance Computing (HPC). NVIDIA established CUDA as a parallel computing architecture controlling and making use of the compute power of GPUs. CUDA provides sufficient support for C++ language elements to enable the Expression Template (ET) technique in the device memory domain. QDP++ is a C++ vector class library suited for quantum field theory which provides vector data types and expressions and forms the basis of the lattice QCD software suite Chroma. In this work accelerating QDP++ expression evaluation to a GPU was successfully implemented leveraging the ET technique and using Just-In-Time (JIT) compilation. The Portable Expression Template Engine (PETE) and the C API for CUDA kernel arguments were used to build the bridge between host and device memory domains. This provides the possibility to accelerate Chroma routines to a GPU which are typically not subject to special optimisation. As an ...

  6. Accelerators for Cancer Therapy

    Science.gov (United States)

    Lennox, Arlene J.

    2000-05-30

    The vast majority of radiation treatments for cancerous tumors are given using electron linacs that provide both electrons and photons at several energies. Design and construction of these linacs are based on mature technology that is rapidly becoming more and more standardized and sophisticated. The use of hadrons such as neutrons, protons, alphas, or carbon, oxygen and neon ions is relatively new. Accelerators for hadron therapy are far from standardized, but the use of hadron therapy as an alternative to conventional radiation has led to significant improvements and refinements in conventional treatment techniques. This paper presents the rationale for radiation therapy, describes the accelerators used in conventional and hadron therapy, and outlines the issues that must still be resolved in the emerging field of hadron therapy.

  7. Hardware Accelerated Simulated Radiography

    Energy Technology Data Exchange (ETDEWEB)

    Laney, D; Callahan, S; Max, N; Silva, C; Langer, S; Frank, R

    2005-04-12

    We present the application of hardware accelerated volume rendering algorithms to the simulation of radiographs as an aid to scientists designing experiments, validating simulation codes, and understanding experimental data. The techniques presented take advantage of 32 bit floating point texture capabilities to obtain validated solutions to the radiative transport equation for X-rays. An unsorted hexahedron projection algorithm is presented for curvilinear hexahedra that produces simulated radiographs in the absorption-only regime. A sorted tetrahedral projection algorithm is presented that simulates radiographs of emissive materials. We apply the tetrahedral projection algorithm to the simulation of experimental diagnostics for inertial confinement fusion experiments on a laser at the University of Rochester. We show that the hardware accelerated solution is faster than the current technique used by scientists.

  8. NEW ACCELERATION METHODS

    Energy Technology Data Exchange (ETDEWEB)

    Sessler, A.M.

    1984-07-01

    But a glance at the Livingston chart, Fig. 1, of accelerator particle energy as a function of time shows that the energy has steadily, exponentially, increased. Equally significant is the fact that this increase is the envelope of diverse technologies. If one is to stay on, or even near, the Livingston curve in future years then new acceleration techniques need to be developed. What are the new acceleration methods? In these two lectures I would like to sketch some of these new ideas. I am well aware that they will probably not result in high energy accelerators within this or the next decade, but conversely, it is likely that these ideas will form the basis for the accelerators of the next century. Anyway, the ideas are stimulating and suffice to show that accelerator physicists are not just 'engineers', but genuine scientists deserving to be welcomed into the company of high energy physicists. I believe that outsiders will find this field surprisingly fertile and, certainly fun. To put it more personally, I very much enjoy working in this field and lecturing on it. There are a number of review articles which should be consulted for references to the original literature. In addition there are three books on the subject. Given this material, I feel free to not completely reference the material in the remainder of this article; consultation of the review articles and books will be adequate as an introduction to the literature for references abound (hundreds are given). At last, by way of introduction, I should like to quote from the end of Ref. 2 for I think the remarks made there are most germane. Remember that the talk was addressed to accelerator physicists: 'Finally, it is often said, I think by physicists who are not well-informed, that accelerator builders have used up their capital and now are bereft of ideas, and as a result, high energy physics will eventually--rather soon, in fact--come to a halt. After all, one can't build too many

  9. Future Accelerator Magnet Needs

    CERN Document Server

    Devred, Arnaud; Yamamoto, A

    2005-01-01

    Superconducting magnet technology is continually evolving in order to meet the demanding needs of new accelerators and to provide necessary upgrades for existing machines. A variety of designs are now under development, including high fields and gradients, rapid cycling and novel coil configurations. This paper presents a summary of R&D programs in the EU, Japan and the USA. A performance comparison between NbTi and Nb3Sn along with fabrication and cost issues are also discussed.

  10. Accelerated plate tectonics.

    Science.gov (United States)

    Anderson, D L

    1975-03-21

    The concept of a stressed elastic lithospheric plate riding on a viscous asthenosphere is used to calculate the recurrence interval of great earthquakes at convergent plate boundaries, the separation of decoupling and lithospheric earthquakes, and the migration pattern of large earthquakes along an arc. It is proposed that plate motions accelerate after great decoupling earthquakes and that most of the observed plate motions occur during short periods of time, separated by periods of relative quiescence.

  11. LEP copper accelerating cavities

    CERN Multimedia

    Laurent Guiraud

    1999-01-01

    These copper cavities were used to generate the radio frequency electric field that was used to accelerate electrons and positrons around the 27-km Large Electron-Positron (LEP) collider at CERN, which ran from 1989 to 2000. The copper cavities were gradually replaced from 1996 with new superconducting cavities allowing the collision energy to rise from 90 GeV to 200 GeV by mid-1999.

  12. French nuclear physics accelerator opens

    Science.gov (United States)

    Dumé, Belle

    2016-12-01

    A new €140m particle accelerator for nuclear physics located at the French Large Heavy Ion National Accelerator (GANIL) in Caen was inaugurated last month in a ceremony attended by French president François Hollande.

  13. Accelerated Profile HMM Searches.

    Directory of Open Access Journals (Sweden)

    Sean R Eddy

    2011-10-01

    Full Text Available Profile hidden Markov models (profile HMMs and probabilistic inference methods have made important contributions to the theory of sequence database homology search. However, practical use of profile HMM methods has been hindered by the computational expense of existing software implementations. Here I describe an acceleration heuristic for profile HMMs, the "multiple segment Viterbi" (MSV algorithm. The MSV algorithm computes an optimal sum of multiple ungapped local alignment segments using a striped vector-parallel approach previously described for fast Smith/Waterman alignment. MSV scores follow the same statistical distribution as gapped optimal local alignment scores, allowing rapid evaluation of significance of an MSV score and thus facilitating its use as a heuristic filter. I also describe a 20-fold acceleration of the standard profile HMM Forward/Backward algorithms using a method I call "sparse rescaling". These methods are assembled in a pipeline in which high-scoring MSV hits are passed on for reanalysis with the full HMM Forward/Backward algorithm. This accelerated pipeline is implemented in the freely available HMMER3 software package. Performance benchmarks show that the use of the heuristic MSV filter sacrifices negligible sensitivity compared to unaccelerated profile HMM searches. HMMER3 is substantially more sensitive and 100- to 1000-fold faster than HMMER2. HMMER3 is now about as fast as BLAST for protein searches.

  14. Berkeley Proton Linear Accelerator

    Science.gov (United States)

    Alvarez, L. W.; Bradner, H.; Franck, J.; Gordon, H.; Gow, J. D.; Marshall, L. C.; Oppenheimer, F. F.; Panofsky, W. K. H.; Richman, C.; Woodyard, J. R.

    1953-10-13

    A linear accelerator, which increases the energy of protons from a 4 Mev Van de Graaff injector, to a final energy of 31.5 Mev, has been constructed. The accelerator consists of a cavity 40 feet long and 39 inches in diameter, excited at resonance in a longitudinal electric mode with a radio-frequency power of about 2.2 x 10{sup 6} watts peak at 202.5 mc. Acceleration is made possible by the introduction of 46 axial "drift tubes" into the cavity, which is designed such that the particles traverse the distance between the centers of successive tubes in one cycle of the r.f. power. The protons are longitudinally stable as in the synchrotron, and are stabilized transversely by the action of converging fields produced by focusing grids. The electrical cavity is constructed like an inverted airplane fuselage and is supported in a vacuum tank. Power is supplied by 9 high powered oscillators fed from a pulse generator of the artificial transmission line type.

  15. Optimizing accelerator technology

    CERN Multimedia

    Katarina Anthony

    2012-01-01

    A new EU-funded research and training network, oPAC, is bringing together 22 universities, research centres and industry partners to optimize particle accelerator technology. CERN is one of the network’s main partners and will host 5 early-stage researchers in the BE department.   A diamond detector that will be used for novel beam diagnostics applications in the oPAC project based at CIVIDEC. (Image courtesy of CIVIDEC.) As one of the largest Marie Curie Initial Training Networks ever funded by the EU – to the tune of €6 million – oPAC extends well beyond the particle physics community. “Accelerator physics has become integral to research in almost every scientific discipline – be it biology and life science, medicine, geology and material science, or fundamental physics,” explains Carsten P. Welsch, oPAC co-ordinator based at the University of Liverpool. “By optimizing the operation of accelerators, all of these...

  16. Particle Accelerator Focus Automation

    Directory of Open Access Journals (Sweden)

    Lopes José

    2017-08-01

    Full Text Available The Laboratório de Aceleradores e Tecnologias de Radiação (LATR at the Campus Tecnológico e Nuclear, of Instituto Superior Técnico (IST has a horizontal electrostatic particle accelerator based on the Van de Graaff machine which is used for research in the area of material characterization. This machine produces alfa (He+ and proton (H+ beams of some μA currents up to 2 MeV/q energies. Beam focusing is obtained using a cylindrical lens of the Einzel type, assembled near the high voltage terminal. This paper describes the developed system that automatically focuses the ion beam, using a personal computer running the LabVIEW software, a multifunction input/output board and signal conditioning circuits. The focusing procedure consists of a scanning method to find the lens bias voltage which maximizes the beam current measured on a beam stopper target, which is used as feedback for the scanning cycle. This system, as part of a wider start up and shut down automation system built for this particle accelerator, brings great advantages to the operation of the accelerator by turning it faster and easier to operate, requiring less human presence, and adding the possibility of total remote control in safe conditions.

  17. Particle Accelerator Focus Automation

    Science.gov (United States)

    Lopes, José; Rocha, Jorge; Redondo, Luís; Cruz, João

    2017-08-01

    The Laboratório de Aceleradores e Tecnologias de Radiação (LATR) at the Campus Tecnológico e Nuclear, of Instituto Superior Técnico (IST) has a horizontal electrostatic particle accelerator based on the Van de Graaff machine which is used for research in the area of material characterization. This machine produces alfa (He+) and proton (H+) beams of some μA currents up to 2 MeV/q energies. Beam focusing is obtained using a cylindrical lens of the Einzel type, assembled near the high voltage terminal. This paper describes the developed system that automatically focuses the ion beam, using a personal computer running the LabVIEW software, a multifunction input/output board and signal conditioning circuits. The focusing procedure consists of a scanning method to find the lens bias voltage which maximizes the beam current measured on a beam stopper target, which is used as feedback for the scanning cycle. This system, as part of a wider start up and shut down automation system built for this particle accelerator, brings great advantages to the operation of the accelerator by turning it faster and easier to operate, requiring less human presence, and adding the possibility of total remote control in safe conditions.

  18. Introduction to Microwave Linear [Accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Whittum, David H

    1999-01-04

    The elements of microwave linear accelerators are introduced starting with the principles of acceleration and accelerating structures. Considerations for microwave structure modeling and design are developed from an elementary point of view. Basic elements of microwave electronics are described for application to the accelerator circuit and instrumentation. Concepts of beam physics are explored together with examples of common beamline instruments. Charged particle optics and lattice diagnostics are introduced. Considerations for fixed-target and colliding-beam experimentation are summarized.

  19. Plasma accelerator experiments in Yugoslavia

    Science.gov (United States)

    Purić, J.; Astashynski, V. M.; Kuraica, M. M.; Dojčinovié, I. P.

    2002-12-01

    An overview is given of the results obtained in the Plasma Accelerator Experiments in Belgrade, using quasi-stationary high current plasma accelerators constructed within the framework of the Yugoslavia-Belarus Joint Project. So far, the following plasma accelerators have been realized: Magnetoplasma Compressor type (MPC); MPC Yu type; one stage Erosive Plasma Dynamic System (EPDS) and, in final stage of construction two stage Quasi-Stationary High Current Plasma Accelerator (QHPA).

  20. Novel multiplex format of an extended multilocus variable-number-tandem-repeat analysis of Clostridium difficile correlates with tandem repeat sequence typing.

    Science.gov (United States)

    Jensen, Mie Birgitte Frid; Engberg, Jørgen; Larsson, Jonas T; Olsen, Katharina E P; Torpdahl, Mia

    2015-03-01

    Subtyping of Clostridium difficile is crucial for outbreak investigations. An extended multilocus variable-number tandem-repeat analysis (eMLVA) of 14 variable number tandem repeat (VNTR) loci was validated in multiplex format compatible with a routine typing laboratory and showed excellent concordance with tandem repeat sequence typing (TRST) and high discriminatory power.

  1. Accelerating in de Sitter spacetimes

    CERN Document Server

    Cotaescu, Ion I

    2014-01-01

    We propose a definition of uniform accelerated frames in de Sitter spacetimes exploiting the Nachtmann group theoretical method of introducing coordinates on these manifolds. Requiring the transformation between the static frame and the accelerated one to depend continuously on acceleration in order to recover the well-known Rindler approach in the flat limit, we obtain a result with a reasonable physical meaning.

  2. The impact of genome triplication on tandem gene evolution in Brassica rapa

    Directory of Open Access Journals (Sweden)

    Lu eFang

    2012-11-01

    Full Text Available Whole genome duplication (WGD and tandem duplication (TD are both important modes of gene expansion. However, how whole genome duplication influences tandemly duplicated genes is not well studied. We used Brassica rapa, which has undergone an additional genome triplication (WGT and shares a common ancestor with Arabidopsis thaliana, Arabidopsis lyrata and Thellungiella parvula, to investigate the impact of genome triplication on tandem gene evolution. We identified 2,137, 1,569, 1,751 and 1,135 tandem gene arrays in B. rapa, A. thaliana, A. lyrata and T. parvula respectively. Among them, 414 conserved tandem arrays are shared by the 3 species without WGT, which were also considered as existing in the diploid ancestor of B. rapa. Thus, after genome triplication, B. rapa should have 1,242 tandem arrays according to the 414 conserved tandems. Here, we found 400 out of the 414 tandems had at least one syntenic ortholog in the genome of B. rapa. Furthermore, 294 out of the 400 shared syntenic orthologs maintain tandem arrays (more than one gene for each syntenic hit in B. rapa. For the 294 tandem arrays, we obtained 426 copies of syntenic paralogous tandems in the triplicated genome of B. rapa. In this study, we demonstrated that tandem arrays in B. rapa were dramatically fractionated after WGT when compared either to non-tandem genes in the B. rapa genome or to the tandem arrays in closely related species that have not experienced a recent whole-genome polyploidization event.

  3. Muon Acceleration - RLA and FFAG

    Energy Technology Data Exchange (ETDEWEB)

    Bogacz, Alex

    2011-10-01

    Various acceleration schemes for muons are presented. The overall goal of the acceleration systems: large acceptance acceleration to 25 GeV and 'beam shaping' can be accomplished by various fixed field accelerators at different stages. They involve three superconducting linacs: a single pass linear Pre-accelerator followed by a pair of multi-pass Recirculating Linear Accelerators (RLA) and finally a non-scaling FFAG ring. The present baseline acceleration scenario has been optimized to take maximum advantage of appropriate acceleration scheme at a given stage. The solenoid based Pre-accelerator offers very large acceptance and facilitates correction of energy gain across the bunch and significant longitudinal compression trough induced synchrotron motion. However, far off-crest acceleration reduces the effective acceleration gradient and adds complexity through the requirement of individual RF phase control for each cavity. The RLAs offer very efficient usage of high gradient superconducting RF and ability to adjust path-length after each linac pass through individual return arcs with uniformly periodic FODO optics suitable for chromatic compensation of emittance dilution with sextupoles. However, they require spreaders/recombiners switchyards at both linac ends and significant total length of the arcs. The non-scaling Fixed Field Alternating Gradient (FFAG) ring combines compactness with very large chromatic acceptance (twice the injection energy) and it allows for large number of passes through the RF (at least eight, possibly as high as 15).

  4. VLHC accelerator physics

    Energy Technology Data Exchange (ETDEWEB)

    Michael Blaskiewicz et al.

    2001-11-01

    A six-month design study for a future high energy hadron collider was initiated by the Fermilab director in October 2000. The request was to study a staged approach where a large circumference tunnel is built that initially would house a low field ({approx}2 T) collider with center-of-mass energy greater than 30 TeV and a peak (initial) luminosity of 10{sup 34} cm{sup -2}s{sup -1}. The tunnel was to be scoped, however, to support a future upgrade to a center-of-mass energy greater than 150 TeV with a peak luminosity of 2 x 10{sup 34} cm{sup -2} sec{sup -1} using high field ({approx} 10 T) superconducting magnet technology. In a collaboration with Brookhaven National Laboratory and Lawrence Berkeley National Laboratory, a report of the Design Study was produced by Fermilab in June 2001. 1 The Design Study focused on a Stage 1, 20 x 20 TeV collider using a 2-in-1 transmission line magnet and leads to a Stage 2, 87.5 x 87.5 TeV collider using 10 T Nb{sub 3}Sn magnet technology. The article that follows is a compilation of accelerator physics designs and computational results which contributed to the Design Study. Many of the parameters found in this report evolved during the study, and thus slight differences between this text and the Design Study report can be found. The present text, however, presents the major accelerator physics issues of the Very Large Hadron Collider as examined by the Design Study collaboration and provides a basis for discussion and further studies of VLHC accelerator parameters and design philosophies.

  5. APT accelerator. Topical report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence, G.; Rusthoi, D. [comp.] [ed.

    1995-03-01

    The Accelerator Production of Tritium (APT) project, sponsored by Department of Energy Defense Programs (DOE/DP), involves the preconceptual design of an accelerator system to produce tritium for the nation`s stockpile of nuclear weapons. Tritium is an isotope of hydrogen used in nuclear weapons, and must be replenished because of radioactive decay (its half-life is approximately 12 years). Because the annual production requirements for tritium has greatly decreased since the end of the Cold War, an alternative approach to reactors for tritium production, based on a linear accelerator, is now being seriously considered. The annual tritium requirement at the time this study was undertaken (1992-1993) was 3/8 that of the 1988 goal, usually stated as 3/8-Goal. Continued reduction in the number of weapons in the stockpile has led to a revised (lower) production requirement today (March, 1995). The production requirement needed to maintain the reduced stockpile, as stated in the recent Nuclear Posture Review (summer 1994) is approximately 3/16-Goal, half the previous level. The Nuclear Posture Review also requires that the production plant be designed to accomodate a production increase (surge) to 3/8-Goal capability within five years, to allow recovery from a possible extended outage of the tritium plant. A multi-laboratory team, collaborating with several industrial partners, has developed a preconceptual APT design for the 3/8-Goal, operating at 75% capacity. The team has presented APT as a promising alternative to the reactor concepts proposed for Complex-21. Given the requirements of a reduced weapons stockpile, APT offers both significant safety, environmental, and production-fexibility advantages in comparison with reactor systems, and the prospect of successful development in time to meet the US defense requirements of the 21st Century.

  6. Accelerated Innovation Pilot

    Science.gov (United States)

    Davis, Jeffrey

    2012-01-01

    Opportunities: I. Engage NASA team (examples) a) Research and technology calls . provide suggestions to AES, HRP, OCT. b) Use NASA@Work to solicit other ideas; (possibly before R+D calls). II. Stimulate collaboration (examples) a) NHHPC. b) Wharton Mack Center for Technological Innovation (Feb 2013). c) International ] DLR ] :envihab (July 2013). d) Accelerated research models . NSF, Myelin Repair Foundation. III. Engage public Prizes (open platform: InnoCentive, yet2.com, NTL; Rice Business Plan, etc.) IV. Use same methods to engage STEM.

  7. Accelerating abelian gauge dynamics

    CERN Document Server

    Adler, Stephen Louis

    1991-01-01

    In this paper, we suggest a new acceleration method for Abelian gauge theories based on linear transformations to variables which weight all length scales equally. We measure the autocorrelation time for the Polyakov loop and the plaquette at β=1.0 in the U(1) gauge theory in four dimensions, for the new method and for standard Metropolis updates. We find a dramatic improvement for the new method over the Metropolis method. Computing the critical exponent z for the new method remains an important open issue.

  8. 2014 CERN Accelerator Schools

    CERN Multimedia

    2014-01-01

    A specialised school on Power Converters will be held in Baden, Switzerland, from 7 to 14 May 2014. Please note that the deadline for applications is 7 FEBRUARY 2014. A course on Introduction to Accelerator Physics will be held in Prague, Czech Republic, from 31 August to 12 September 2014. Applications are now open for this school; the application deadline is 25 APRIL 2014. Further information on these schools and other CAS events can be found on the CAS website and on the Indico page. For further information please contact Barbara.strasser@cern.ch

  9. Hardware Accelerated Power Estimation

    CERN Document Server

    Coburn, Joel; Raghunathan, Anand

    2011-01-01

    In this paper, we present power emulation, a novel design paradigm that utilizes hardware acceleration for the purpose of fast power estimation. Power emulation is based on the observation that the functions necessary for power estimation (power model evaluation, aggregation, etc.) can be implemented as hardware circuits. Therefore, we can enhance any given design with "power estimation hardware", map it to a prototyping platform, and exercise it with any given test stimuli to obtain power consumption estimates. Our empirical studies with industrial designs reveal that power emulation can achieve significant speedups (10X to 500X) over state-of-the-art commercial register-transfer level (RTL) power estimation tools.

  10. Medical applications of accelerators

    CERN Document Server

    Rossi, Sandro

    1998-01-01

    At Present, about five thousands accelerators are devoted to biomedical applications. They are mainly used in radiotherapy, research and medical radioisotopes production. In this framework oncological hadron-therapy deserves particular attention since it represents a field in rapid evolution thanks to the joint efforts of laboratories with long experiences in particle physics. It is the case of CERN where the design of an optimised synchrotron for medical applications has been pursued. These lectures present these activities with particular attention to the new developments which are scientifically interesting and/or economically promising.

  11. ACCELERATING NANO-TECHNOLOGICAL

    DEFF Research Database (Denmark)

    Jensen, Jens Stissing; Koch, Christian

    2007-01-01

    By viewing the construction industry as a technological innovation system (TIS) this paper discusses possible initiatives to accelerate nanotechnological innovations. The point of departure is a recent report on the application of nano-technology in the Danish construction industry, which concludes...... of the system are furthermore poorly equipped at identifying potentials within high-tech areas. In order to exploit the potentials of nano-technology it is thus argued that an alternative TIS needs to be established. Initiatives should identify and support “incubation rooms” or marked niches in order...

  12. Design of a new tandem wings hybrid airship

    Science.gov (United States)

    Li, Feng; Ye, ZhengYin; Gao, Chao

    2012-10-01

    It is scientifically important science value and engineering promising to develop the buoyancy-lift integrated hybrid airship for high attitude platform. Through the numerical method, a new tandem wings hybrid airship with both higher utility value and economy efficiency was obtained and its total performance and technical parameters were analyzed in detail. In order to further improve the lift-drag characteristics, we implemented the optimization design for aerodynamic configuration of tandem wings hybrid airship via the response surface method. The results indicate that the tandem wings hybrid airship has considerable volume efficiency and higher aerodynamic characteristics. After optimization, the lift-drag ratio of this hybrid airship was increased by 6.08%. In a given gross lift condition, tandem wings hybrid airship may provide more payload and specific productivity. Furthermore, the size of tandem airship is smaller so the demand for skin flexible materials can be reduced. Results of this study could serve as a new approach to designing buoyancy-lifting integrated hybrid airship.

  13. High-Efficiency Polycrystalline Thin Film Tandem Solar Cells.

    Science.gov (United States)

    Kranz, Lukas; Abate, Antonio; Feurer, Thomas; Fu, Fan; Avancini, Enrico; Löckinger, Johannes; Reinhard, Patrick; Zakeeruddin, Shaik M; Grätzel, Michael; Buecheler, Stephan; Tiwari, Ayodhya N

    2015-07-16

    A promising way to enhance the efficiency of CIGS solar cells is by combining them with perovskite solar cells in tandem devices. However, so far, such tandem devices had limited efficiency due to challenges in developing NIR-transparent perovskite top cells, which allow photons with energy below the perovskite band gap to be transmitted to the bottom cell. Here, a process for the fabrication of NIR-transparent perovskite solar cells is presented, which enables power conversion efficiencies up to 12.1% combined with an average sub-band gap transmission of 71% for photons with wavelength between 800 and 1000 nm. The combination of a NIR-transparent perovskite top cell with a CIGS bottom cell enabled a tandem device with 19.5% efficiency, which is the highest reported efficiency for a polycrystalline thin film tandem solar cell. Future developments of perovskite/CIGS tandem devices are discussed and prospects for devices with efficiency toward and above 27% are given.

  14. Accelerator-based research activities at 'Centro Nacional de Aceleradores', Seville (Spain)

    Energy Technology Data Exchange (ETDEWEB)

    Respaldiza, M.A. [Centro Nacional de Aceleradores, Avd. Thomas A. Edison 7, E-41092 Sevilla (Spain); Departmento de Fisica Atomica, Molecular y Nuclear, Universidad de Sevilla, Sevilla (Spain)], E-mail: respaldiza@us.es; Ager, F.J. [Centro Nacional de Aceleradores, Avd. Thomas A. Edison 7, E-41092 Sevilla (Spain); Departmento de Fisica Aplicada I, Universidad de Sevilla, Sevilla (Spain); Carmona, A. [Centro Nacional de Aceleradores, Avd. Thomas A. Edison 7, E-41092 Sevilla (Spain); Laboratoire de Chimie Nucleaire Analytique et Bioenvironnementale, Universite de Bordeaux (France); Ferrer, J. [Centro Nacional de Aceleradores, Avd. Thomas A. Edison 7, E-41092 Sevilla (Spain); Garcia-Leon, M.; Garcia-Lopez, J. [Centro Nacional de Aceleradores, Avd. Thomas A. Edison 7, E-41092 Sevilla (Spain); Departmento de Fisica Atomica, Molecular y Nuclear, Universidad de Sevilla, Sevilla (Spain); Garcia-Orellana, I. [Centro Nacional de Aceleradores, Avd. Thomas A. Edison 7, E-41092 Sevilla (Spain); Gomez-Tubio, B. [Centro Nacional de Aceleradores, Avd. Thomas A. Edison 7, E-41092 Sevilla (Spain); Departmento de Fisica Aplicada III, Universidad de Sevilla, Sevilla (Spain); Morilla, Y. [Centro Nacional de Aceleradores, Avd. Thomas A. Edison 7, E-41092 Sevilla (Spain); Ontalba, M.A. [Centro Nacional de Aceleradores, Avd. Thomas A. Edison 7, E-41092 Sevilla (Spain); Departmento de Fisica, Universidad de Extremadura, Caceres (Spain); Ortega-Feliu, I. [Centro Nacional de Aceleradores, Avd. Thomas A. Edison 7, E-41092 Sevilla (Spain); Departmento de Fisica Atomica, Molecular y Nuclear, Universidad de Sevilla, Sevilla (Spain)

    2008-05-15

    In February 1998, almost 10 years ago, the set-up of the first IBA (ion beam analysis) facility in Spain took place with the arrival of a 3 MV tandem accelerator [J. Garcia-Lopez, F.J. Ager, M. Barbadillo-Rank, F.J. Madrigal, M.A. Ontalba, M.A. Respaldiza, M.D. Ynsa, Nucl. Instr. and Meth. B 161-163 (2000) 1137]. Since then, an intensive research program using IBA techniques has been carried out. Subsequently, a cyclotron for 18 MeV protons has been also installed at the 'Centro Nacional de Aceleradores' (CNA), devoted mainly to isotope production for PET (positron emission tomography) techniques, but possibly applied to material analysis and damage studies on a dedicated beam line. Moreover, a 1 MV tandem has been recently installed for AMS (accelerator mass spectrometry) {sup 14}C dating and environmental research with other isotopes. In the present paper we describe the new facilities and the developments of the 3 MV tandem beam lines occurred during the past years, as well as some examples of the most recent research activities in our Center in the fields of Material Science, Archaeometry, Biomedicine and Environment.

  15. Development of small applied accelerator in Tokyo Institute of Technology

    CERN Document Server

    Hattori, T

    2002-01-01

    Interdigital-H(IH) Linac was constructed and applied to materials research in the University. IH Linac uses 1.6 MV small tandem pelletron and accelerates ion (>Q/A=1/4) from 240 KeV to 2.4 MeV. The secondary IH Linac was built and increased the energy to 3.4 MeV/u. In order to apply linac to therapy, IH Linac for PET (Position Emission Tomography), Carbon 6 MeV/u Linac for cancer therapy, APF (Alternating Phase Focus)-IH prototype linac, Carbon 2 MeV/u test APF-IH linac were developed. On application to semiconductor and industry, IHQ type MeV ion implantation device, APF-IH type MeV ion implantation device and high-energy electron accelerator were developed. A bone density measurement instrument was developed and the data was proved better values than ordinary instrument. The problems of prototype small accelerator are summarized. (S.Y.)

  16. Acceleration without Temperature

    CERN Document Server

    Doria, Alaric

    2015-01-01

    We show that while some non-uniformly accelerating observers (NUAOs) do indeed see a Bose-Einstein distribution of particles for the expectation value of the number operator in the Minkowski vacuum state, the density matrix is non-thermal and therefore a definition of temperature is not warranted. This is due to the fact that our NUAOs do not see event horizons in the spacetime. More specifically, the Minkowski vacuum state is perceived by our NUAOs as a single-mode squeezed state as opposed to the two-mode squeezed state characteristic of uniformly accelerating observers. Both single and two-mode squeezed states are pure quantum states; however, tracing over degrees of freedom in one of the modes of the two-mode squeezed state reduces the pure density matrix to a thermal density matrix. It is this property in the two-mode squeezed state that allows one to consistently define a temperature. In the single-mode case, an equivalent tracing is neither required nor available.

  17. Particle acceleration mechanisms

    CERN Document Server

    Petrosyan, V

    2008-01-01

    We review the possible mechanisms for production of non-thermal electrons which are responsible for non-thermal radiation in clusters of galaxies. Our primary focus is on non-thermal Bremsstrahlung and inverse Compton scattering, that produce hard X-ray emission. We briefly review acceleration mechanisms and point out that in most astrophysical situations, and in particular for the intracluster medium, shocks, turbulence and plasma waves play a crucial role. We consider two scenarios for production of non-thermal radiation. The first is hard X-ray emission due to non-thermal Bremsstrahlung by nonrelativistic particles. Non-thermal tails are produced by accelerating electrons from the background plasma with an initial Maxwellian distribution. However, these tails are accompanied by significant heating and they are present for a short time of <10^6 yr, which is also the time that the tail will be thermalised. Such non-thermal tails, even if possible, can only explain the hard X-ray but not the radio emission...

  18. Accelerator School Success

    CERN Multimedia

    2004-01-01

    Accelerator specialists don't grow on trees: training them is the job of the CERN Accelerator School (CAS). Group photo during visit to the Daresbury Laboratory. CAS and the CCLRC Daresbury Laboratory jointly organised a specialised school on Power Converters in Warrington, England from 12-18 May 2004. The last CAS Power Converter course was in 1990, so there was plenty of ground to cover. The challenging programme proposed a review of the state of the art and the latest developments in the field, including 30 hours of tuition. The school also included a visit to the CCLRC Daresbury laboratory, a one-day excursion to Liverpool and Chester and a themed (Welsh medieval) dinner at the school's closure. A record attendance of 91 students of more than 20 different nationalities included not only participants from Europe and North America but also from Armenia, Taiwan, India, Turkey, Iran and for the first time, fee-paying students from China and Australia. European industry showed a welcome and solid interest in...

  19. Acceleration in Linear and Circular Motion

    Science.gov (United States)

    Kellington, S. H.; Docherty, W.

    1975-01-01

    Describes the construction of a simple accelerometer and explains its use in demonstrating acceleration, deceleration, constant speed, measurement of acceleration, acceleration and the inclined plane and angular and radial acceleration. (GS)

  20. 2014 Joint International Accelerator School: Beam Loss and Accelerator Protection

    CERN Document Server

    JAS - Joint US-CERN-Japan-Russia Accelerator School

    2016-01-01

    Many particle accelerators operate with very high beam power and very high energy stored in particle beams as well as in magnet systems. In the future, the beam power in high intensity accelerators will further increase. The protection of the accelerator equipment from the consequences of uncontrolled release of the energy is essential. This was the motivation for organizing a first school on beam losses and accelerator protection (in general referred to as machine protection). During the school the methods and technologies to identify, mitigate, monitor and manage the technical risks associated with the operation of accelerators with high-power beams or subsystems with large stored energy were presented. At the completion of the school the participants should have been able to understand the physical phenomena that can damage machine subsystems or interrupt operations and to analyze an accelerator facility to produce a register of technical risks and the corresponding risk mitigation and management strategie...

  1. Counter-Rotating Tandem Motor Drilling System

    Energy Technology Data Exchange (ETDEWEB)

    Kent Perry

    2009-04-30

    Gas Technology Institute (GTI), in partnership with Dennis Tool Company (DTC), has worked to develop an advanced drill bit system to be used with microhole drilling assemblies. One of the main objectives of this project was to utilize new and existing coiled tubing and slimhole drilling technologies to develop Microhole Technology (MHT) so as to make significant reductions in the cost of E&P down to 5000 feet in wellbores as small as 3.5 inches in diameter. This new technology was developed to work toward the DOE's goal of enabling domestic shallow oil and gas wells to be drilled inexpensively compared to wells drilled utilizing conventional drilling practices. Overall drilling costs can be lowered by drilling a well as quickly as possible. For this reason, a high drilling rate of penetration is always desired. In general, high drilling rates of penetration (ROP) can be achieved by increasing the weight on bit and increasing the rotary speed of the bit. As the weight on bit is increased, the cutting inserts penetrate deeper into the rock, resulting in a deeper depth of cut. As the depth of cut increases, the amount of torque required to turn the bit also increases. The Counter-Rotating Tandem Motor Drilling System (CRTMDS) was planned to achieve high rate of penetration (ROP) resulting in the reduction of the drilling cost. The system includes two counter-rotating cutter systems to reduce or eliminate the reactive torque the drillpipe or coiled tubing must resist. This would allow the application of maximum weight-on-bit and rotational velocities that a coiled tubing drilling unit is capable of delivering. Several variations of the CRTDMS were designed, manufactured and tested. The original tests failed leading to design modifications. Two versions of the modified system were tested and showed that the concept is both positive and practical; however, the tests showed that for the system to be robust and durable, borehole diameter should be substantially larger

  2. Dosimetric comparison of tandem and Ovoids vs. tandem and ring for intracavitary gynecologic applications.

    Science.gov (United States)

    Levin, Daphne; Menhel, Janna; Rabin, Tanya; Pfeffer, M Raphael; Symon, Zvi

    2008-01-01

    We evaluated dosimetric differences in tandem and ovoid (TO) and tandem and ring (TR) gynecologic brachytherapy applicators. Seventeen patients with cervical cancer (Stages II-IV) receiving 3 high-dose-rate (HDR) brachytherapy applications (both TO and TR) were studied. Patients underwent computed tomography (CT) scans with contrast in bladder, and were prescribed 8 Gy to ICRU points A, with additional optimization goals of maintaining the pear-shaped dose distribution and minimizing bladder and rectum doses. Bladder and rectum point doses, mean, and maximum doses were calculated. Total treatment time and volumes treated to 95%, 85%, 50%, and 20% or the prescription dose were compared. There were no significant differences between TO and TR applicators in doses to prescription points or critical organs. However, there were significant differences (p < 0.001) between the applicators in treated volumes and total treatment time. The TO treated larger volumes over a longer time. Within each patient, when the applicators were compared, treated volumes were also found to be significantly different (p < 0.01, chi(2)). Our results demonstrate that the 2 applicators, while delivering the prescribed dose to points A and keeping critical organ doses below tolerance, treat significantly different volumes. It is unclear if this difference is clinically meaningful. TO applicators may be treating surrounding healthy tissue unnecessarily, or TR applicators may be underdosing tumor tissue. Further investigation with appropriate imaging modalities is required for accurate delineation of target volumes. Clearly, the TO and TR are not identical, and should not be used interchangeably without further study.

  3. Detection of long-lived plutonium isotopes in environmental samples by Accelerator Mass Spectrometry (AMS)

    Energy Technology Data Exchange (ETDEWEB)

    Hain, Karin; Faestermann, Thomas; Fimiani, Leticia; Gomez Guzman, Jose Manuel; Korschinek, Gunther; Ludwig, Peter [Technische Universitaet Muenchen (Germany); Shinonaga, Taeko [Helmholtz Zentrum Muenchen (Germany)

    2013-07-01

    The Plutonium isotopes {sup 239}Pu (T{sub 1/2}=2.4.10{sup 4}a), {sup 240}Pu (T{sub 1/2}=6.5.10{sup 3}a) and {sup 242}Pu (T{sub 1/2}=3.7.10{sup 5}a) are anthropogenic radionuclides emitted into the environment by nuclear activities. Pu is accumulated in the human body and hence, poses a considerable hazard to human health. Due to the long half-lives, these isotopes are present in the biosphere on large time scales and a build-up can be expected. Therefore it is important to study the contamination pathway of Pu into the drinking water. At the Maier-Leibnitz-Laboratory in Munich a method to detect long-lived Pu isotopes by Accelerator Mass Spectrometry (AMS) is being developed. AMS requires only few milligrams of sample material, which is a substantial advantage over decay counting techniques. Consequently, more samples from different locations can be taken which is essential when searching for locally increased Pu concentrations as in the Pacific Ocean after the Fukushima accident in March 2011. Samples from different locations in the Pacific Ocean and from the snow-hydrosphere are planned to be investigated by AMS. The principle detection method using AMS and an overview of the status of the project is presented.

  4. Accelerator Based Neutron Beams for Neutron Capture Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Yanch, Jacquelyn C.

    2003-04-11

    The DOE-funded accelerator BNCT program at the Massachusetts Institute of Technology has resulted in the only operating accelerator-based epithermal neutron beam facility capable of generating significant dose rates in the world. With five separate beamlines and two different epithermal neutron beam assemblies installed, we are currently capable of treating patients with rheumatoid arthritis in less than 15 minutes (knee joints) or 4 minutes (finger joints) or irradiating patients with shallow brain tumors to a healthy tissue dose of 12.6 Gy in 3.6 hours. The accelerator, designed by Newton scientific Incorporated, is located in dedicated laboratory space that MIT renovated specifically for this project. The Laboratory for Accelerator Beam Applications consists of an accelerator room, a control room, a shielded radiation vault, and additional laboratory space nearby. In addition to the design, construction and characterization of the tandem electrostatic accelerator, this program also resulted in other significant accomplishments. Assemblies for generating epithermal neutron beams were designed, constructed and experimentally evaluated using mixed-field dosimetry techniques. Strategies for target construction and target cooling were implemented and tested. We demonstrated that the method of submerged jet impingement using water as the coolant is capable of handling power densities of up to 6 x 10(sup 7) W/m(sup 2) with heat transfer coefficients of 10(sup 6)W/m(sup 2)-K. Experiments with the liquid metal gallium demonstrated its superiority compared with water with little effect on the neutronic properties of the epithermal beam. Monoenergetic proton beams generated using the accelerator were used to evaluate proton RBE as a function of LET and demonstrated a maximum RBE at approximately 30-40 keV/um, a finding consistent with results published by other researchers. We also developed an experimental approach to biological intercomparison of epithermal beams and

  5. Tandem photovoltaic solar cells and increased solar energy conversion efficiency

    Science.gov (United States)

    Loferski, J. J.

    1976-01-01

    Tandem photovoltaic cells, as proposed by Jackson (1955) to increase the efficiency of solar energy conversion, involve the construction of a system of stacked p/n homojunction photovoltaic cells composed of different semiconductors. It had been pointed out by critics, however, that the total power which could be extracted from the cells in the stack placed side by side was substantially greater than the power obtained from the stacked cells. A reexamination of the tandem cell concept in view of the development of the past few years is conducted. It is concluded that the use of tandem cell systems in flat plate collectors, as originally envisioned by Jackson, may yet become feasible as a result of the development of economically acceptable solar cells for large scale terrestrial power generation.

  6. Flatness and Profile Integration Control Model for Tandem Cold Mills

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Using the effective matrix methods of flatness and profile control synthetically, the flatness and profile in- tegration control scheme for tandem cold mills is built in order to increase flatness and profile control precision of tan- dem cold mills. Corresponding control strategies are adopted for various control objectives of different stands and the coordination control strategies of various stands are given, which makes the on-line flatness control cooperate with on-line profile control and implements the parallel control of different stands. According to the measured flatness and profile data of some 1550 mm tandem cold mills, the control scheme is verified and the result indicates that the scheme has high flatness and profile control precision with steady and reliable control process. A new way and method is supplied for researching shade control of tandem cold mills.

  7. Tandem photovoltaic solar cells and increased solar energy conversion efficiency

    Science.gov (United States)

    Loferski, J. J.

    1976-01-01

    Tandem photovoltaic cells, as proposed by Jackson (1955) to increase the efficiency of solar energy conversion, involve the construction of a system of stacked p/n homojunction photovoltaic cells composed of different semiconductors. It had been pointed out by critics, however, that the total power which could be extracted from the cells in the stack placed side by side was substantially greater than the power obtained from the stacked cells. A reexamination of the tandem cell concept in view of the development of the past few years is conducted. It is concluded that the use of tandem cell systems in flat plate collectors, as originally envisioned by Jackson, may yet become feasible as a result of the development of economically acceptable solar cells for large scale terrestrial power generation.

  8. A periodic table of symmetric tandem mismatches in RNA.

    Science.gov (United States)

    Wu, M; McDowell, J A; Turner, D H

    1995-03-14

    The stabilities and structures of a series of RNA octamers containing symmetric tandem mismatches were studied by UV melting and imino proton NMR. The free energy increments for tandem mismatch formation are found to depend upon both mismatch sequence and adjacent base pairs. The observed sequence dependence of tandem mismatch stability is UGGU > GUUG > GAAG > or = AGGA > UUUU > CAAC > or = CUUC approximately UCCU approximately CCCC approximately ACCA approximately AAAA, and the closing base pair dependence is 5'G3'C > 5'C3'G > 5'U3'A approximately 5'A3'U. These results differ from expectations based on models used in RNA folding algorithms and from the sequence dependence observed for folding of RNA hairpins. Imino proton NMR results indicate the sequence dependence is partially due to hydrogen bonding within mismatches.

  9. Highly Loaded Fan by Using Tandem Cascade Rotor Blade

    Science.gov (United States)

    Hasegawa, Hiroaki; Suga, Shinya; Matsuoka, Akinori

    For axial flow compressors and fans in the aircraft engines higher pressure ratio is required in order to attain the high thrust engines. In this study, the fan with the tandem cascades was introduced to increase the fan pressure ratio. The use of tandem cascades in the fan allows savings in length and weight and therefore a compact fan could be built. The design of fan with tandem cascades and the fan testing were carried out to develop the high pressure ratio fan for the Air Turbo Ramjet (ATR) propulsion system. The ATR is a combined cycle engine which performs like a turbojet engine at subsonic speeds and a ramjet at supersonic speeds. In particular, high fan pressure ratio contributes to increase the engine thrust during subsonic flight at which the engine does not make use of ram effect. The results of the fan testing indicate that the pressure ratio of 2.2 is achieved in single stage fan.

  10. Investigation on laser accelerators. Plasma beat wave accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Miura, Akihiko; Miyamoto, Yasuaki; Hagiwara, Masayoshi; Suzuki, Mitsutoshi; Sudo, Osamu [Power Reactor and Nuclear Fuel Development Corp., Tokai, Ibaraki (Japan). Tokai Works

    1998-04-01

    Laser accelerator technology has characteristics of high energy, compact, short pulse and high luminescence{center_dot}low emittance. This means potential many applications in wide ranges of fields as well as high energy and nuclear physics. High power short laser pulses are injected to a plasma in the typical example of laser accelerators. Large electric fields are induced in the plasma. Electrons in the plasma are accelerated with the ponderomotive force of the electric field. The principles of interaction on beat wave, wakefield accelerators, inverse free electron laser and inverse Cherenkov radiation are briefly introduced. The overview of plasma beat wave accelerator study is briefly described on the programs at Chalk River Laboratories(Canada), UCLA(USA), Osaka Univ. (Japan) and Ecole Polytechnique (France). Issues of the plasma beat wave accelerator are discussed from the viewpoint of application. Existing laser technologies of CO{sub 2}, YAG and YFL are available for the present day accelerator technology. An acceleration length of beat wave interaction is limited due to its phase condition. Ideas on multi-staged acceleration using the phasing plasma fiber are introduced. (Y. Tanaka)

  11. CERN Accelerator School: Registration open for Advanced Accelerator Physics course

    CERN Multimedia

    2015-01-01

    Registration is now open for the CERN Accelerator School’s Advanced Accelerator Physics course to be held in Warsaw, Poland from 27 September to 9 October 2015.   The course will be of interest to physicists and engineers who wish to extend their knowledge of accelerator physics. The programme offers core lectures on accelerator physics in the mornings and a practical course with hands-on tuition in the afternoons.  Further information can be found at: http://cas.web.cern.ch/cas/Poland2015/Warsaw-advert.html http://indico.cern.ch/event/361988/

  12. CERN Accelerator School: Registration open for Advanced Accelerator Physics course

    CERN Multimedia

    2015-01-01

    Registration is now open for the CERN Accelerator School’s Advanced Accelerator Physics course to be held in Warsaw, Poland from 27 September to 9 October 2015.   The course will be of interest to physicists and engineers who wish to extend their knowledge of Accelerator Physics. The programme offers core lectures on accelerator physics in the mornings and a practical course with hands-on tuition in the afternoons.  Further information can be found at: http://cas.web.cern.ch/cas/Poland2015/Warsaw-advert.html http://indico.cern.ch/event/361988/

  13. Accelerator mass spectrometer with ion selection in high-voltage terminal

    Science.gov (United States)

    Rastigeev, S. A.; Goncharov, A. D.; Klyuev, V. F.; Konstantinov, E. S.; Kutnyakova, L. A.; Parkhomchuk, V. V.; Petrozhitskii, A. V.; Frolov, A. R.

    2016-12-01

    The folded electrostatic tandem accelerator with ion selection in a high-voltage terminal is the basis of accelerator mass spectrometry (AMS) at the BINP. Additional features of the BINP AMS are the target based on magnesium vapors as a stripper without vacuum deterioration and a time-of-flight telescope with thin films for reliable ion identification. The acceleration complex demonstrates reliable operation in a mode of 1 MV with 50 Hz counting rate of 14C+3 radiocarbon for modern samples (14C/12C 1.2 × 10-12). The current state of the AMS has been considered and the experimental results of the radiocarbon concentration measurements in test samples have been presented.

  14. 巧筑园林播芬芳--记1983年慕尼黑国际园艺展中国园“芳华园”%Fanghua Garden:China Garden in Munich International Horticultural Exhibition1983

    Institute of Scientific and Technical Information of China (English)

    王缺

    2015-01-01

    In 1983, the Guangzhou Municipal Bureau of Parks represented our country in the international horticultural exhibition in Munich ,Germany. Works of Fanghua Garden design inherite the traditional Lingnan Garden style, dismantle some of the limitations and according to local conditions, rockery and water, use plants and stone, frame garden appropriately with the poetic. It is designed and built in a foreign country as the first open-air gardens.It is the first step towards modern Chinese landscape architecture into the world which has enthusiastic response internationally.%1983年,广州市园林局代表国家参加德国慕尼黑的国际园艺展。作品“芳华园”的设计手法既传承了岭南园林传统风格,也打破了某些局限,因地制宜,叠山理水,巧用植物和石景,构园得体,融入诗情画意。它是我国在国外自行设计建造的第一座露天园林,是近现代中国园林走向世界的第一步,国际上反响热烈。

  15. Status of the LLL tandem-shaped charge designs

    Energy Technology Data Exchange (ETDEWEB)

    Godfrey, C.S.; Jandrisevits, R.A.

    1979-02-22

    Lawrence Livermore Laboratory has been engaged in the design of tandem or multistage shaped charges for several years. Analytical and experimental work that focuses on how several aspects of tandem designs affect the jet characteristics is described. The work demonstrates the effectiveness of analytical methodology to specify liner geometries to achieve jets with controlled velocity gradients and high overall efficiency. It also shows that jet clippers and other ancillary components, along with controlled liner thickness, help make clean breaks between the jet and the slug and facilitate insertion of a second jet. Second-stage initiation and interjet time delays are discussed.

  16. Electrostatic accelerators fundamentals and applications

    CERN Document Server

    2005-01-01

    Electrostatic accelerators are an important and widespread subgroup within the broad spectrum of modern, large particle acceleration devices. They are specifically designed for applications that require high-quality ion beams in terms of energy stability and emittance at comparatively low energies (a few MeV). Their ability to accelerate virtually any kind of ion over a continuously tunable range of energies make them a highly versatile tool for investigations in many research fields including, but not limited to, atomic and nuclear spectroscopy, heavy ion reactions, accelerator mass spectroscopy as well as ion-beam analysis and modification. The book is divided into three parts. The first part concisely introduces the field of accelerator technology and techniques that emphasize their major modern applications. The second part treats the electrostatic accelerator per se: its construction and operational principles as well as its maintenance. The third part covers all relevant applications in which electrosta...

  17. Testing Gravity on Accelerators

    CERN Document Server

    Kalaydzhyan, Tigran

    2016-01-01

    Weak equivalence principle (WEP) is one of the cornerstones of the modern theories of gravity, stating that the trajectory of a freely falling test body is independent of its internal structure and composition. Even though WEP is known to be valid for the normal matter with a high precision, it has never been experimentally confirmed for relativistic matter and antimatter. We make an attempt to constrain possible deviations from WEP utilizing the modern accelerator technologies. We analyze the (absence of) vacuum Cherenkov radiation, photon decay, anomalous synchrotron losses and the Compton spectra to put limits on the isotropic Lorentz violation and further convert them to the constraints on the difference between the gravitational and inertial masses of the relativistic electrons/positrons. Our main result is the 0.1% limit on the mentioned difference.

  18. SPS accelerating cavity

    CERN Multimedia

    1976-01-01

    The SPS started up with 2 accelerating cavities (each consisting of 5 tank sections) in LSS3. They have a 200 MHz travelling wave structure (see 7411032 and 7802190) and 750 kW of power is fed to each of the cavities from a 1 MW tetrode power amplifier, located in a surface building above, via a coaxial transmission line. Clemens Zettler, builder of the SPS RF system, is standing at the side of one of the cavities. In 1978 and 1979 another 2 cavities were added and entered service in 1980. These were part of the intensity improvement programme and served well for the new role of the SPS as proton-antiproton collider. See also 7411032, 8011289, 8104138, 8302397.

  19. Dynamics of pyroelectric accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Ghaderi, R.; Davani, F. Abbasi, E-mail: fabbasi@sbu.ac.ir [Radiation Application Department, Shahid Beheshti University, Tehran (Iran, Islamic Republic of)

    2015-01-26

    Pyroelectric crystals are used to produce high energy electron beams. We have derived a method to model electric potential generation on LiTaO{sub 3} crystal during heating cycle. In this method, effect of heat transfer on the potential generation is investigated by some experiments. In addition, electron emission from the crystal surface is modeled by measurements and analysis. These spectral data are used to present a dynamic equation of electric potential with respect to thickness of the crystal and variation of its temperature. The dynamic equation's results for different thicknesses are compared with measured data. As a result, to attain more energetic electrons, best thickness of the crystals could be extracted from the equation. This allows for better understanding of pyroelectric crystals and help to study about current and energy of accelerated electrons.

  20. HIGH ENERGY PARTICLE ACCELERATOR

    Science.gov (United States)

    Courant, E.D.; Livingston, M.S.; Snyder, H.S.

    1959-04-14

    An improved apparatus is presented for focusing charged particles in an accelerator. In essence, the invention includes means for establishing a magnetic field in discrete sectors along the path of moving charged particles, the magnetic field varying in each sector in accordance with the relation. B = B/ sub 0/ STAln (r-r/sub 0/)/r/sub 0/!, where B/sub 0/ is the value of the magnetic field at the equilibrium orbit of radius r/sub 0/ of the path of the particles, B equals the magnetic field at the radius r of the chamber and n equals the magnetic field gradient index, the polarity of n being abruptly reversed a plurality of times as the particles travel along their arcuate path. With this arrangement, the particles are alternately converged towards the axis of their equillbrium orbit and diverged therefrom in successive sectors with a resultant focusing effect.

  1. Acceleration of cosmic rays

    Energy Technology Data Exchange (ETDEWEB)

    Berezhko, E [Yu.G. Shafer Institute of Cosmophysical Research and Aeronomy, 31 Lenin Ave., 677980 Yakutsk (Russian Federation)], E-mail: berezhko@ikfia.ysn.ru

    2008-07-15

    Cosmic ray (CR) origin problem is briefly discussed. It is argued that CRs with energies up to 10{sup 17} eV are produced in galactic supernova remnants, whereas ultra high energy CRs are extragalactic. CR composition strongly changes within the transition from galactic to extragalactic CR component, therefore precise measurements of CR composition at energies 10{sup 17} - 10{sup 19} eV are needed for the reliable determination of this transition. The possible sources of extragalactic CRs are briefly discussed. It is argued that CR acceleration at the shock created by the expanding cocoons around active galactic nuclei has to be considered as a prime candidate for the sources of extragalactic CRs.

  2. Hadron accelerators for radiotherapy

    Science.gov (United States)

    Owen, Hywel; MacKay, Ranald; Peach, Ken; Smith, Susan

    2014-04-01

    Over the last twenty years the treatment of cancer with protons and light nuclei such as carbon ions has moved from being the preserve of research laboratories into widespread clinical use. A number of choices now exist for the creation and delivery of these particles, key amongst these being the adoption of pencil beam scanning using a rotating gantry; attention is now being given to what technologies will enable cheaper and more effective treatment in the future. In this article the physics and engineering used in these hadron therapy facilities is presented, and the research areas likely to lead to substantive improvements. The wider use of superconducting magnets is an emerging trend, whilst further ahead novel high-gradient acceleration techniques may enable much smaller treatment systems. Imaging techniques to improve the accuracy of treatment plans must also be developed hand-in-hand with future sources of particles, a notable example of which is proton computed tomography.

  3. Accelerator based fusion reactor

    Science.gov (United States)

    Liu, Keh-Fei; Chao, Alexander Wu

    2017-08-01

    A feasibility study of fusion reactors based on accelerators is carried out. We consider a novel scheme where a beam from the accelerator hits the target plasma on the resonance of the fusion reaction and establish characteristic criteria for a workable reactor. We consider the reactions d+t\\to n+α,d+{{}3}{{H}\\text{e}}\\to p+α , and p+{{}11}B\\to 3α in this study. The critical temperature of the plasma is determined from overcoming the stopping power of the beam with the fusion energy gain. The needed plasma lifetime is determined from the width of the resonance, the beam velocity and the plasma density. We estimate the critical beam flux by balancing the energy of fusion production against the plasma thermo-energy and the loss due to stopping power for the case of an inert plasma. The product of critical flux and plasma lifetime is independent of plasma density and has a weak dependence on temperature. Even though the critical temperatures for these reactions are lower than those for the thermonuclear reactors, the critical flux is in the range of {{10}22}-{{10}24}~\\text{c}{{\\text{m}}-2}~{{\\text{s}}-1} for the plasma density {ρt}={{10}15}~\\text{c}{{\\text{m}}-3} in the case of an inert plasma. Several approaches to control the growth of the two-stream instability are discussed. We have also considered several scenarios for practical implementation which will require further studies. Finally, we consider the case where the injected beam at the resonance energy maintains the plasma temperature and prolongs its lifetime to reach a steady state. The equations for power balance and particle number conservation are given for this case.

  4. Collective accelerator for electron colliders

    Energy Technology Data Exchange (ETDEWEB)

    Briggs, R.J.

    1985-05-13

    A recent concept for collective acceleration and focusing of a high energy electron bunch is discussed, in the context of its possible applicability to large linear colliders in the TeV range. The scheme can be considered to be a member of the general class of two-beam accelerators, where a high current, low voltage beam produces the acceleration fields for a trailing high energy bunch.

  5. Landing the uniformly accelerating observers

    OpenAIRE

    Rothenstein, Bernhard; Popescu, Stefan; Gruber, Ronald P.

    2006-01-01

    Observers of the uniformly accelerating observers or the observers who make up the system of uniformly accelerating observers reach the same velocity V at different times ti which depends on V and on theirs acceleration gi. Considering a platform that moves with constant velocity V, the observers can land smoothly on it. Their ages and locations in the inertial reference frame attached to the platform are reckoned and compared.

  6. NIIEFA accelerators for applied purposes

    Science.gov (United States)

    Vorogushin, M. F.; Strokach, A. P.; Filatov, O. G.

    2016-12-01

    Since the foundation of the institute, we have designed and delivered more than three hundred different accelerators to Russia and abroad: cyclotrons, linear accelerators, and neutron generators. The technical characteristics of our equipment makes it competitive on the international market. Here we present the application, main parameters, and status of accelerators manufactured by NIIEFA, as well as prospects for the development of electrophysical systems for applied purposes.

  7. Project X: Accelerator Reference Design

    CERN Document Server

    Holmes, S D; Chase, B; Gollwitzer, K; Johnson, D; Kaducak, M; Klebaner, A; Kourbanis, I; Lebedev, V; Leveling, A; Li, D; Nagaitsev, S; Ostroumov, P; Pasquinelli, R; Patrick, J; Prost, L; Scarpine, V; Shemyakin, A; Solyak, N; Steimel, J; Yakovlev, V; Zwaska, R

    2013-01-01

    Part 1 of "Project X: Accelerator Reference Design, Physics Opportunities, Broader Impacts". Part 1 contains the volume Preface and a description of the conceptual design for a high-intensity proton accelerator facility being developed to support a world-leading program of Intensity Frontier physics over the next two decades at Fermilab. Subjects covered include performance goals, the accelerator physics design, and the technological basis for such a facility.

  8. Thomas Precession by Uniform Acceleration

    CERN Document Server

    Pardy, Miroslav

    2015-01-01

    We determine the nonlinear transformations between coordinate systems which are mutually in a constant symmetrical accelerated motion. The maximal acceleration limit follows from the kinematical origin and it is an analogue of the maximal velocity in special relativity. We derive the dependence of mass, length, time, Doppler effect, Cherenkov effect and transition radiation angle on acceleration as an analogue phenomena in special theory of relativity. The last application of our method is the Thomas precession by uniform acceleration with the possible role in the modern physics and cosmology. The comparison of derived results with other relativistic methods is necessary.

  9. Superconducting Radiofrequency (SRF) Acceleration Technology

    Data.gov (United States)

    Federal Laboratory Consortium — SRF cavities enable accelerators to increase particle beam energy levels while minimizing the use of electrical power by all but eliminating electrical resistance....

  10. Awakening acceleration: AWAKE’s plasma cell arrive

    CERN Multimedia

    CERN Audiovisual Productions Service; Paola Catapano; Jacques Fichet; Paola Catapano

    2016-01-01

    Interview with Edda Gschwendtner, project leader of the AWAKE collaboration, on the day the AWAKE's plasma cell is transported from the surface hall were it was tested (EHN1 on CERN Prevessin) to the AWAKE tunnel in CERN's SPS decay tunnel. The Plasma Cell was built by the Max Planck Institute in Munich.

  11. Acceleration parameters for fluid physics with accelerating bodies

    CSIR Research Space (South Africa)

    Gledhill, Irvy MA

    2016-06-01

    Full Text Available to an acceleration parameter that appears to be new in fluid physics, but is known in cosmology. A selection of cases for rectilinear acceleration has been chosen to illustrate the point that this parameter alone does not govern regimes of flow about significantly...

  12. SHORT ACCELERATION TIMES FROM SUPERDIFFUSIVE SHOCK ACCELERATION IN THE HELIOSPHERE

    Energy Technology Data Exchange (ETDEWEB)

    Perri, S.; Zimbardo, G., E-mail: silvia.perri@fis.unical.it [Dipartimento di Fisica, Università della Calabria, Ponte P. Bucci, I-87036 Rende (Italy)

    2015-12-10

    The analysis of time profiles of particles accelerated at interplanetary shocks allows particle transport properties to be inferred. The frequently observed power-law decay upstream, indeed, implies a superdiffusive particle transport when the level of magnetic field variance does not change as the time interval from the shock front increases. In this context, a superdiffusive shock acceleration (SSA) theory has been developed, allowing us to make predictions of the acceleration times. In this work we estimate for a number of interplanetary shocks, including the solar wind termination shock, the acceleration times for energetic protons in the framework of SSA and we compare the results with the acceleration times predicted by standard diffusive shock acceleration. The acceleration times due to SSA are found to be much shorter than in the classical model, and also shorter than the interplanetary shock lifetimes. This decrease of the acceleration times is due to the scale-free nature of the particle displacements in the framework of superdiffusion. Indeed, very long displacements are possible, increasing the probability for particles far from the front of the shock to return, and short displacements have a high probability of occurrence, increasing the chances for particles close to the front to cross the shock many times.

  13. Tandem neopentyl glycol maltosides (TNMs) for membrane protein stabilisation

    DEFF Research Database (Denmark)

    Bae, Hyoung Eun; Mortensen, Jonas S; Ribeiro, Orquidea

    2016-01-01

    A novel class of detergents, designated tandem neopentyl glycol maltosides (TNMs), were evaluated with four target membrane proteins. The best detergent varied depending on the target, but TNM-C12L and TNM-C11S were notable for their ability to confer increased membrane protein stability compared...

  14. PCR-free digital minisatellite tandem repeat genotyping.

    Science.gov (United States)

    Chen, Yuchao; Seo, Tae Seok

    2011-06-01

    We demonstrated a proof-of-concept for novel minisatellite tandem repeat typing, called PCR-free digital VNTR (variable number tandem repeat) typing, which is composed of three steps: a ligation reaction instead of PCR thermal cycling, magnetic bead-based solid-phase capture for purification, and an elongated sample stacking microcapillary electrophoresis (μCE) for sensitive digital coding of repeat number. We designed a 16-bp fluorescently labeled ligation probe which is complementary to a repeat unit of a biotinylated synthetic template mimicking the human D1S80 VNTR locus and is randomly hybridized with the minisatellite tandem repeats. A quick isothermal ligation reaction was followed to link the adjacent ligation probes on the DNA templates, and then the ligated products were purified by streptavidin-coated magnetic beads. After a denaturing step, a large amount of ligated products whose size difference was equivalent to the repeat unit were released and recovered. Through the elongated sample stacking μCE separation on a microdevice, the fluorescence signal of the ligated products was generated in the electropherogram and the peak number was directly counted which was exactly matched with the repeat number of VNTR locus. We could successfully identify the minisatellite tandem repeat number with only 5 fmol of DNA template in 30 min.

  15. Bio-olefins from unsaturated fatty acids via tandem catalysis

    Science.gov (United States)

    A new catalytic route to bio-olefins from unsaturated fatty acids will be described. At the heart of the process, the catalyst apparently functions in a tandem mode by both dynamically isomerizing the positions of double bonds in an aliphatic chain and, subsequently, decarboxylating specific isomers...

  16. Design considerations for the Tandem Junction Solar Cell

    Science.gov (United States)

    Matzen, W. T.; Carbajal, B. G.; Hardy, R. W.

    1979-01-01

    Structure and operation of the tandem junction cell (TJC) are described. The impact of using only back contacts is discussed. A model is presented which explains operation of the TJC in terms of transistor action. The model is applied to predict TJC performance as a function of physical parameters.

  17. Interim report on the tandem mirror hybrid design study

    Energy Technology Data Exchange (ETDEWEB)

    Moir, R.W. (ed.)

    1979-08-01

    The initial phase of a 2-year design study of a tandem mirror fusion reactor is presented. The following chapters are included: (1) mechanical design of the plant; (2) plasma physics; (3) blanket design; (4) magnet design; (5) injector design; (6) direct convertor design; (7) balance of plant design; (8) fission burner reactor; (9) environment and safety; and (10) economic analysis. (MOW)

  18. Tandem fluid queues fed by homogeneous on-off sources

    NARCIS (Netherlands)

    Scheinhardt, Willem R.W.; Aalto, Samuli

    2000-01-01

    We consider a tandem fluid model with multiple consecutive buffers. The input of buffer j+1 is the output from buffer j, while the first buffer is fed by a, possibly infinite, number of independent homogeneous on–off sources. The sources have exponentially distributed silent periods and generally di

  19. Crux: rapid open source protein tandem mass spectrometry analysis.

    Science.gov (United States)

    McIlwain, Sean; Tamura, Kaipo; Kertesz-Farkas, Attila; Grant, Charles E; Diament, Benjamin; Frewen, Barbara; Howbert, J Jeffry; Hoopmann, Michael R; Käll, Lukas; Eng, Jimmy K; MacCoss, Michael J; Noble, William Stafford

    2014-10-03

    Efficiently and accurately analyzing big protein tandem mass spectrometry data sets requires robust software that incorporates state-of-the-art computational, machine learning, and statistical methods. The Crux mass spectrometry analysis software toolkit ( http://cruxtoolkit.sourceforge.net ) is an open source project that aims to provide users with a cross-platform suite of analysis tools for interpreting protein mass spectrometry data.

  20. Near-optimal switching strategies for a tandem queue

    NARCIS (Netherlands)

    Leeuwen, D. van; Núñez Queija, R.; Boucherie, R.J.; van Dijk, N.M.

    2015-01-01

    Motivated by various applications in logistics, road traffic and production management, we investigate two versions of a tandem queueing model in which the service rate of the first queue can be controlled. The objective is to keep the mean number of jobs in the second queue as low as possible, with

  1. Ultimate performance of polymer: Fullerene bulk heterojunction tandem solar cells

    NARCIS (Netherlands)

    Kotlarski, J.D.; Blom, P.W.M.

    2011-01-01

    We present the model calculations to explore the potential of polymer:fullerene tandem solar cells. As an approach we use a combined optical and electrical device model, where the absorption profiles are used as starting point for the numerical current-voltage calculations. With this model a maximum

  2. Tandem, roostes sild ja erinnüsed / Andres Langemets

    Index Scriptorium Estoniae

    Langemets, Andres, 1948-

    2002-01-01

    Arvustus: Tandem. Pegasus on pisut pervers. Tln. : Perioodika, 2002. (Loomingu Raamatukogu ; 1) ; Sild, Ivar. Minu erünnised. Tallinn : LauaPealne, 2002 ; Rooste, Jürgen. Igapäevane Psyhho : kalendaarium et mõista elu / kujund. Mammut. I. k. : Sulemees, 2001

  3. II-IV-V Based Thin Film Tandem Photovoltaic Cell

    Energy Technology Data Exchange (ETDEWEB)

    Newman, Nathan [Arizona State Univ., Mesa, AZ (United States); van Schilfgaarde, Mark [Arizona State Univ., Mesa, AZ (United States)

    2012-10-04

    [Through a combination of theory and experiment that, absent unknown mitigating factors, a tandem cell whose (wide-gap. 1.8 eV) top layer is made of ZnSnP2 and whose (narrow gap, 1.1 eV) bottom layer consisting of ZnGeAs2 are near-ideal materials for a tandem cell. Not only are there gaps optimally adjusted to the solar spectrum, but the two compounds are lattice-matched, and their energy band structure and optical absorption are also near-ideal (they closely resemble that of GaAs). Our first major challenge is to establish that high-quality II-IV-V thin films can be synthesized. We have begun growing and characterizing films of ZnGeAs2 and ZnSnP2, initially grown on Ge substrates (the lattice constant of Ge matches these compounds) by pulsed laser ablation and sputtering. In tandem are theoretical calculations to guide the experiments. The goal is to develop methods that can be used to produce a pair of lattice-matched thin films that will be useful in tandem cells.

  4. Tandem, roostes sild ja erinnüsed / Andres Langemets

    Index Scriptorium Estoniae

    Langemets, Andres, 1948-

    2002-01-01

    Arvustus: Tandem. Pegasus on pisut pervers. Tln. : Perioodika, 2002. (Loomingu Raamatukogu ; 1) ; Sild, Ivar. Minu erünnised. Tallinn : LauaPealne, 2002 ; Rooste, Jürgen. Igapäevane Psyhho : kalendaarium et mõista elu / kujund. Mammut. I. k. : Sulemees, 2001

  5. Tandem chemiluminescence-flow injection analysis for dimethoate determination.

    OpenAIRE

    Catalá Icardo, Mónica; López Paz, José Luis; CHOVES BARÓN, CRISTINA

    2010-01-01

    Ministry of Education and Science [CTM2006-11991] FEDER funds Catalá Icardo, M.; López Paz, JL.; Choves Barón, C. (2010). Tandem chemiluminescence-flow injection analysis for dimethoate determination. Luminescence. 25:235-236. doi:10.1002/bio.1217. Senia 235 236 25

  6. State-dependent importance sampling for a Jackson tandem network

    NARCIS (Netherlands)

    Miretskiy, D.I.; Scheinhardt, W.R.W.; Mandjes, M.R.H.

    2008-01-01

    This paper considers importance sampling as a tool for rare-event simulation. The focus is on estimating the probability of overflow in the downstream queue of a Jacksonian two-node tandem queue – it is known that in this setting ‘traditional’ stateindependent importance-sampling distributions perfo

  7. State-dependent importance sampling for a Jackson tandem network

    NARCIS (Netherlands)

    Miretskiy, D.I.; Scheinhardt, W.R.W.; Mandjes, M.R.H.

    2008-01-01

    This paper considers importance sampling as a tool for rare-event simulation. The focus is on estimating the probability of overflow in the downstream queue of a Jacksonian two-node tandem queue – it is known that in this setting ‘traditional’ state-independent importance-sampling distributions perf

  8. State-dependent importance sampling for a Jackson tandem network

    NARCIS (Netherlands)

    Miretskiy, Denis; Scheinhardt, Werner; Mandjes, Michel

    2010-01-01

    This article considers importance sampling as a tool for rare-event simulation. The focus is on estimating the probability of overflow in the downstream queue of a Jacksonian two-node tandem queue; it is known that in this setting “traditional” state-independent importance-sampling distributions per

  9. State-dependent importance sampling for a Jackson tandem network

    NARCIS (Netherlands)

    D. Miretskiy; W. Scheinhardt; M. Mandjes

    2010-01-01

    This article considers importance sampling as a tool for rare-event simulation. The focus is on estimating the probability of overflow in the downstream queue of a Jacksonian two-node tandem queue; it is known that in this setting "traditional" state-independent importance-sampling distributions per

  10. Thomas Edison Accelerated Elementary School.

    Science.gov (United States)

    Levin, Henry M.; Chasin, Gene

    This paper describes early outcomes of a Sacramento, California, elementary school that participated in the Accelerated Schools Project. The school, which serves many minority and poor students, began training for the project in 1992. Accelerated Schools were designed to advance the learning rate of students through a gifted and talented approach,…

  11. Acceleration effects on missile aerodynamics

    CSIR Research Space (South Africa)

    Gledhill, Irvy MA

    2010-09-01

    Full Text Available Practical requirements are now arising in which significant acceleration takes place during flight; 5th generation missiles, such as A-Darter, execute turns at 100 g, where g is the acceleration due to gravity, and thrust from propulsion systems may...

  12. COMPASS Accelerator Design Technical Overview

    Energy Technology Data Exchange (ETDEWEB)

    Nanni, Emilio; Dolgashev, Valery; Tantawi, Sami; Neilson, Jeff; /SLAC

    2016-03-14

    This report is a survey of technical options for generating a MeV-class accelerator for space based science applications. The survey was performed focusing on the primary technical requirements of the accelerator in the context of a satellite environment with its unique challenges of limited electrical power (PE), thermal isolation, dimensions, payload requirement and electrical isolation.

  13. EXHIBITION: Accelerated Particles

    CERN Multimedia

    2004-01-01

    An exhibition of plastic arts and two evenings of performances by sound and visual artists as part of CERN's 50th anniversary celebrations. Fifty candles for CERN, an international laboratory renowned for fundamental research, is a cause for celebration. Since March this year, Geneva and neighbouring parts of France have been the venues for a wealth of small and large-scale events, which will continue until November. Given CERN's location in the commune of Meyrin, the ForuMeyrin is hosting exhibitions of plastic arts and performances entitled: Accelerated Particles. Several works will be exhibited and performed in two 'salons'. Salon des matières: An exhibition of plastic arts From Tues 12 October to Wed 3 November 2004 Tuesdays to Fridays: 16:00 to 19:00 Saturdays: 14:00 to 18:00 Exhibition open late on performance nights, entrance free Salon des particules: Musical and visual performances Tues 12 and Mon 25 October from 20:00 to 23:00 Preview evening for both events: Tues 12 October from 18:...

  14. Actinides, accelerators and erosion

    Science.gov (United States)

    Tims, S. G.; Fifield, L. K.

    2012-10-01

    Fallout isotopes can be used as artificial tracers of soil erosion and sediment accumulation. The most commonly used isotope to date has been 137Cs. Concentrations of 137Cs are, however, significantly lower in the Southern Hemisphere, and furthermore have now declined to 35% of original values due to radioactive decay. As a consequence the future utility of 137Cs is limited in Australia, with many erosion applications becoming untenable within the next 20 years, and there is a need to replace it with another tracer. Plutonium could fill this role, and has the advantages that there were six times as many atoms of Pu as of 137Cs in fallout, and any loss to decay has been negligible due to the long half-lives of the plutonium isotopes. Uranium-236 is another long-lived fallout isotope with significant potential for exploitation as a tracer of soil and sediment movement. Uranium is expected to be more mobile in soils than plutonium (or caesium), and hence the 236U/Pu ratio will vary with soil depth, and so could provide an independent measure of the amount of soil loss. In this paper we discuss accelerator based ultra-sensitive measurements of plutonium and 236U isotopes and their advantages over 137Cs as tracers of soil erosion and sediment movement.

  15. Energy Innovation Acceleration Program

    Energy Technology Data Exchange (ETDEWEB)

    Wolfson, Johanna [Fraunhofer USA Inc., Center for Sustainable Energy Systems, Boston, MA (United States)

    2015-06-15

    The Energy Innovation Acceleration Program (IAP) – also called U-Launch – has had a significant impact on early stage clean energy companies in the Northeast and on the clean energy economy in the Northeast, not only during program execution (2010-2014), but continuing into the future. Key results include: Leverage ratio of 105:1; $105M in follow-on funding (upon $1M investment by EERE); At least 19 commercial products launched; At least 17 new industry partnerships formed; At least $6.5M in revenue generated; >140 jobs created; 60% of assisted companies received follow-on funding within 1 year of program completion; In addition to the direct measurable program results summarized above, two primary lessons emerged from our work executing Energy IAP:; Validation and demonstration awards have an outsized, ‘tipping-point’ effect for startups looking to secure investments and strategic partnerships. An ecosystem approach is valuable, but an approach that evaluates the needs of individual companies and then draws from diverse ecosystem resources to fill them, is most valuable of all.

  16. LHC Dipoles Accelerate

    CERN Multimedia

    2001-01-01

    Andrezej Siemko (left), Peter Sievers (centre), and Lucio Rossi (right), have the exciting challenge of preparing and testing 2000 magnets for the LHC. The LHC is going to require a lot of powerful magnets by the time it begins operation in 2006. More specifically, it is going to need 130 special magnets, 400 quadrupoles, and a whopping 1250 dipoles! Preparing and testing these magnets for the conditions they will encounter in the LHC is not an easy task. But evaluation of the most recently received magnet, from the German company Noell, is showing that while the monumental task of receiving and testing nearly 2000 magnets is going to be exhausting, the goals are definitely attainable. At the moment and over the next year, pre-series magnets (the magnets that CERN uses to fine tune performance) are arriving slowly (90 in total will arrive), but by 2003 the rate of series magnet arrival will accelerate to 9 per week, that's over 450 in a single year! And working with these magnets when they arrive is tough. ...

  17. Muon Collider Progress: Accelerators

    CERN Document Server

    Zisman, Michael S

    2011-01-01

    A muon collider would be a powerful tool for exploring the energy-frontier with leptons, and would complement the studies now under way at the LHC. Such a device would offer several important benefits. Muons, like electrons, are point particles so the full center-of-mass energy is available for particle production. Moreover, on account of their higher mass, muons give rise to very little synchrotron radiation and produce very little beamstrahlung. The first feature permits the use of a circular collider that can make efficient use of the expensive rf system and whose footprint is compatible with an existing laboratory site. The second feature leads to a relatively narrow energy spread at the collision point. Designing an accelerator complex for a muon collider is a challenging task. Firstly, the muons are produced as a tertiary beam, so a high-power proton beam and a target that can withstand it are needed to provide the required luminosity of ~1 \\times 10^34 cm^-2s^-1. Secondly, the beam is initially produce...

  18. Actinides, accelerators and erosion

    Directory of Open Access Journals (Sweden)

    Fifield L.K.

    2012-10-01

    Full Text Available Fallout isotopes can be used as artificial tracers of soil erosion and sediment accumulation. The most commonly used isotope to date has been 137Cs. Concentrations of 137Cs are, however, significantly lower in the Southern Hemisphere, and furthermore have now declined to 35% of original values due to radioactive decay. As a consequence the future utility of 137Cs is limited in Australia, with many erosion applications becoming untenable within the next 20 years, and there is a need to replace it with another tracer. Plutonium could fill this role, and has the advantages that there were six times as many atoms of Pu as of 137Cs in fallout, and any loss to decay has been negligible due to the long half-lives of the plutonium isotopes. Uranium-236 is another long-lived fallout isotope with significant potential for exploitation as a tracer of soil and sediment movement. Uranium is expected to be more mobile in soils than plutonium (or caesium, and hence the 236U/Pu ratio will vary with soil depth, and so could provide an independent measure of the amount of soil loss. In this paper we discuss accelerator based ultra-sensitive measurements of plutonium and 236U isotopes and their advantages over 137Cs as tracers of soil erosion and sediment movement.

  19. EXHIBITION: Accelerated Particles

    CERN Multimedia

    2004-01-01

    http://www.cern.ch/cern50/ An exhibition of plastic arts and two evenings of performances by sound and visual artists as part of CERN's fiftieth anniversary celebrations. The fiftieth anniversary of a world famous organization like CERN, an international laboratory specializing in fundamental research, is a cause for celebration. Since March this year, Geneva and neighbouring parts of France have been the venues for a wealth of small and large-scale events, which will continue until November. Given CERN's location in the commune of Meyrin, the ForuMeyrin is hosting two "salons" consisting of an exhibition of plastic arts and evenings of music and visual arts performances with the collective title of "Accelerated Particles". Several works will be exhibited and performed. Salon des matières: An exhibition of plastic arts Until Wednesday 3 November 2004. Tuesdays to Fridays: 4.00 p.m. to 7.00 p.m. Saturdays: 2.00 p.m. to 6.00 p.m. Doors open late on the evening of the performances. Salon des ...

  20. The entangled accelerating universe

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez-Diaz, Pedro F. [Colina de los Chopos, Instituto de Fisica Fundamental, Consejo Superior de Investigaciones Cientificas, Serrano 121, 28006 Madrid (Spain); Estacion Ecologica de Biocosmologia, Pedro de Alvarado, 14, 06411-Medellin (Spain)], E-mail: p.gonzalezdiaz@imaff.cfmac.csic.es; Robles-Perez, Salvador [Colina de los Chopos, Instituto de Fisica Fundamental, Consejo Superior de Investigaciones Cientificas, Serrano 121, 28006 Madrid (Spain); Estacion Ecologica de Biocosmologia, Pedro de Alvarado, 14, 06411-Medellin (Spain)

    2009-08-31

    Using the known result that the nucleation of baby universes in correlated pairs is equivalent to spacetime squeezing, we show in this Letter that there exists a T-duality symmetry between two-dimensional warp drives, which are physically expressible as localized de Sitter little universes, and two-dimensional Tolman-Hawking and Gidding-Strominger baby universes respectively correlated in pairs, so that the creation of warp drives is also equivalent to spacetime squeezing. Perhaps more importantly, it has been also seen that the nucleation of warp drives entails a violation of the Bell's inequalities, and hence the phenomena of quantum entanglement, complementarity and wave function collapse. These results are generalized to the case of any dynamically accelerating universe filled with dark or phantom energy whose creation is also physically equivalent to spacetime squeezing and to the violation of the Bell's inequalities, so that the universe we are living in should be governed by essential sharp quantum theory laws and must be a quantum entangled system.

  1. Accelerated shallow water modeling

    Science.gov (United States)

    Gandham, Rajesh; Medina, David; Warburton, Timothy

    2015-04-01

    ln this talk we will describe our ongoing developments in accelerated numerical methods for modeling tsunamis, and oceanic fluid flows using two dimensional shallow water model and/or three dimensional incompressible Navier Stokes model discretized with high order discontinuous Galerkin methods. High order discontinuous Galerkin methods can be computationally demanding, requiring extensive computational time to simulate real time events on traditional CPU architectures. However, recent advances in computing architectures and hardware aware algorithms make it possible to reduce simulation time and provide accurate predictions in a timely manner. Hence we tailor these algorithms to take advantage of single instruction multiple data (SIMD) architecture that is seen in modern many core compute devices such as GPUs. We will discuss our unified and extensive many-core programming library OCCA that alleviates the need to completely re-design the solvers to keep up with constantly evolving parallel programming models and hardware architectures. We will present performance results for the flow simulations demonstrating performance leveraging multiple different multi-threading APIs on GPU and CPU targets.

  2. SPS RF Accelerating Cavity

    CERN Multimedia

    1979-01-01

    This picture shows one of the 2 new cavities installed in 1978-1979. The main RF-system of the SPS comprises four cavities: two of 20 m length and two of 16.5 m length. They are all installed in one long straight section (LSS 3). These cavities are of the travelling-wave type operating at a centre frequency of 200.2 MHz. They are wideband, filling time about 700 ns and untuned. The power amplifiers, using tetrodes are installed in a surface building 200 m from the cavities. Initially only two cavities were installed, a third cavity was installed in 1978 and a forth one in 1979. The number of power amplifiers was also increased: to the first 2 MW plant a second 2 MW plant was added and by end 1979 there were 8 500 kW units combined in pairs to feed each of the 4 cavities with up to about 1 MW RF power, resulting in a total accelerating voltage of about 8 MV. See also 7412016X, 7412017X, 7411048X

  3. Particle Acceleration in Astrophysical Sources

    CERN Document Server

    Amato, Elena

    2015-01-01

    Astrophysical sources are extremely efficient accelerators. Some sources emit photons up to multi-TeV energies, a signature of the presence, within them, of particles with energies much higher than those achievable with the largest accelerators on Earth. Even more compelling evidence comes from the study of Cosmic Rays, charged relativistic particles that reach the Earth with incredibly high energies: at the highest energy end of their spectrum, these subatomic particles are carrying a macroscopic energy, up to a few Joules. Here I will address the best candidate sources and mechanisms as cosmic particle accelerators. I will mainly focus on Galactic sources such as Supernova Remnants and Pulsar Wind Nebulae, which being close and bright, are the best studied among astrophysical accelerators. These sources are held responsible for most of the energy that is put in relativistic particles in the Universe, but they are not thought to accelerate particles up to the highest individual energies, $\\approx 10^{20}$ eV...

  4. The ISAC post-accelerator

    Science.gov (United States)

    Laxdal, R. E.; Marchetto, M.

    2014-01-01

    The acceleration chain of the ISAC facility boosts the energy of both radioactive and stable light and heavy ions for beam delivery to both a medium energy area in ISAC-I and a high energy area in ISAC-II. The post-accelerator comprises a 35.4 MHz RFQ to accelerate beams of A/q ≤ 30 from 2 keV/u to 150 keV/u and a post stripper, 106.1 MHz variable energy drift tube linac (DTL) to accelerate ions of A/q ≤ 6 to a final energy between 0.15 MeV/u to 1.5 MeV/u. A 40 MV superconducting linac further accelerates beam from 1.5 MeV/u to energies above the Coulomb barrier. All linacs operate cw to preserve beam intensity.

  5. Shear Acceleration in Expanding Flows

    CERN Document Server

    Rieger, F M

    2016-01-01

    Shear flows are naturally expected to occur in astrophysical environments and potential sites of continuous non-thermal Fermi-type particle acceleration. Here we investigate the efficiency of expanding relativistic outflows to facilitate the acceleration of energetic charged particles to higher energies. To this end, the gradual shear acceleration coefficient is derived based on an analytical treatment. The results are applied to the context of the relativistic jets of active galactic nuclei. The inferred acceleration timescale is investigated for a variety of conical flow profiles (i.e., power law, Gaussian, Fermi-Dirac) and compared to the relevant radiative and non-radiative loss timescales. The results exemplify that relativistic shear flows are capable of boosting cosmic-rays to extreme energies. Efficient electron acceleration, on the other hand, requires weak magnetic fields and may thus be accompanied by a delayed onset of particle energization and affect the overall jet appearance (e.g., core, ridge ...

  6. Industrial accelerators and their applications

    CERN Document Server

    Hamm, Marianne E

    2012-01-01

    This unique new book is a comprehensive review of the many current industrial applications of particle accelerators, written by experts in each of these fields. Readers will gain a broad understanding of the principles of these applications, the extent to which they are employed, and the accelerator technology utilized. The book also serves as a thorough introduction to these fields for non-experts and laymen. Due to the increased interest in industrial applications, there is a growing interest among accelerator physicists and many other scientists worldwide in understanding how accelerators are used in various applications. The government agencies that fund scientific research with accelerators are also seeking more information on the many commercial applications that have been or can be developed with the technology developments they are funding. Many industries are also doing more research on how they can improve their products or processes using particle beams.

  7. Beam acceleration through proton radio frequency quadrupole accelerator in BARC

    Science.gov (United States)

    Bhagwat, P. V.; Krishnagopal, S.; Mathew, J. V.; Singh, S. K.; Jain, P.; Rao, S. V. L. S.; Pande, M.; Kumar, R.; Roychowdhury, P.; Kelwani, H.; Rama Rao, B. V.; Gupta, S. K.; Agarwal, A.; Kukreti, B. M.; Singh, P.

    2016-05-01

    A 3 MeV proton Radio Frequency Quadrupole (RFQ) accelerator has been designed at the Bhabha Atomic Research Centre, Mumbai, India, for the Low Energy High Intensity Proton Accelerator (LEHIPA) programme. The 352 MHz RFQ is built in 4 segments and in the first phase two segments of the LEHIPA RFQ were commissioned, accelerating a 50 keV, 1 mA pulsed proton beam from the ion source, to an energy of 1.24 MeV. The successful operation of the RFQ gave confidence in the physics understanding and technology development that have been achieved, and indicate that the road forward can now be traversed rather more quickly.

  8. EDITORIAL: Laser and plasma accelerators Laser and plasma accelerators

    Science.gov (United States)

    Bingham, Robert

    2009-02-01

    This special issue on laser and plasma accelerators illustrates the rapid advancement and diverse applications of laser and plasma accelerators. Plasma is an attractive medium for particle acceleration because of the high electric field it can sustain, with studies of acceleration processes remaining one of the most important areas of research in both laboratory and astrophysical plasmas. The rapid advance in laser and accelerator technology has led to the development of terawatt and petawatt laser systems with ultra-high intensities and short sub-picosecond pulses, which are used to generate wakefields in plasma. Recent successes include the demonstration by several groups in 2004 of quasi-monoenergetic electron beams by wakefields in the bubble regime with the GeV energy barrier being reached in 2006, and the energy doubling of the SLAC high-energy electron beam from 42 to 85 GeV. The electron beams generated by the laser plasma driven wakefields have good spatial quality with energies ranging from MeV to GeV. A unique feature is that they are ultra-short bunches with simulations showing that they can be as short as a few femtoseconds with low-energy spread, making these beams ideal for a variety of applications ranging from novel high-brightness radiation sources for medicine, material science and ultrafast time-resolved radiobiology or chemistry. Laser driven ion acceleration experiments have also made significant advances over the last few years with applications in laser fusion, nuclear physics and medicine. Attention is focused on the possibility of producing quasi-mono-energetic ions with energies ranging from hundreds of MeV to GeV per nucleon. New acceleration mechanisms are being studied, including ion acceleration from ultra-thin foils and direct laser acceleration. The application of wakefields or beat waves in other areas of science such as astrophysics and particle physics is beginning to take off, such as the study of cosmic accelerators considered

  9. Monolithic Parallel Tandem Organic Photovoltaic Cell with Transparent Carbon Nanotube Interlayer

    Science.gov (United States)

    Tanaka, S.; Mielczarek, K.; Ovalle-Robles, R.; Wang, B.; Hsu, D.; Zakhidov, A. A.

    2009-01-01

    We demonstrate an organic photovoltaic cell with a monolithic tandem structure in parallel connection. Transparent multiwalled carbon nanotube sheets are used as an interlayer anode electrode for this parallel tandem. The characteristics of front and back cells are measured independently. The short circuit current density of the parallel tandem cell is larger than the currents of each individual cell. The wavelength dependence of photocurrent for the parallel tandem cell shows the superposition spectrum of the two spectral sensitivities of the front and back cells. The monolithic three-electrode photovoltaic cell indeed operates as a parallel tandem with improved efficiency.

  10. Monolithic Parallel Tandem Organic Photovoltaic Cell with Transparent Carbon Nanotube Interlayer

    Science.gov (United States)

    Tanaka, S.; Mielczarek, K.; Ovalle-Robles, R.; Wang, B.; Hsu, D.; Zakhidov, A. A.

    2009-01-01

    We demonstrate an organic photovoltaic cell with a monolithic tandem structure in parallel connection. Transparent multiwalled carbon nanotube sheets are used as an interlayer anode electrode for this parallel tandem. The characteristics of front and back cells are measured independently. The short circuit current density of the parallel tandem cell is larger than the currents of each individual cell. The wavelength dependence of photocurrent for the parallel tandem cell shows the superposition spectrum of the two spectral sensitivities of the front and back cells. The monolithic three-electrode photovoltaic cell indeed operates as a parallel tandem with improved efficiency.

  11. Accelerated cleanup risk reduction

    Energy Technology Data Exchange (ETDEWEB)

    Knapp, R.B.; Aines, R.M.; Blake, R.G.; Copeland, A.B.; Newmark, R.L.; Tompson, A.F.B.

    1998-02-01

    There is no proven technology for remediating contaminant plume source regions in a heterogeneous subsurface. This project is an interdisciplinary effort to develop the requisite new technologies so that will be rapidly accepted by the remediation community. Our technology focus is hydrous pyrolysis/oxidation (HPO) which is a novel in situ thermal technique. We have expanded this core technology to leverage the action of steam injection and place an in situ microbial filter downstream to intercept and destroy the accelerated movement of contaminated groundwater. Most contaminant plume source regions, including the chlorinated solvent plume at LLNL, are in subsurface media characterized by a wide range in hydraulic conductivity. At LLNL, the main conduits for contaminant transport are buried stream channels composed of gravels and sands; these have a hydraulic conductivity in the range of 10{sup -1} to 10{sup -2} cm/s. Clay and silt units with a hydraulic conductivity of 10{sup -1} to 10{sup -6} cm/s bound these buried channels; these are barriers to groundwater movement and contain the highest contaminant concentrations in the source region. New remediation technologies are required because the current ones preferentially access the high conductivity units. HPO is an innovative process for the in situ destruction of contaminants in the entire subsurface. It operates by the injection of steam. We have demonstrated in laboratory experiments that many contaminants rapidly oxidize to harmless compounds at temperatures easily achieved by injecting steam, provided sufficient dissolved oxygen is present. One important challenge in a heterogeneous source region is getting heat, contaminants, and an oxidizing agent in the same place at the same time. We have used the NUFT computer program to simulate the cyclic injection of steam into a contaminated aquifer for design of a field demonstration. We used an 8 hour, steam/oxygen injection cycle followed by a 56 hour relaxation

  12. Operation of the accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Pardo, R.C.; Batzka, B.; Billquist, P.J. [and others

    1995-08-01

    Fiscal Year 1994 was the first year of seven-day operation since ATLAS became a national user facility in 1985. ATLAS made the most of the opportunity this year by providing 5200 hours of beam on-target to the research program. A record number of 60 experiments were completed and the {open_quotes}facility reliability{close_quotes} remained near the 90% level. Seven-day operation was made possible with the addition to the staff of two operator positions providing single-operator coverage during the weekend period. The normally scheduled coverage was augmented by an on-call list of system experts who respond to emergencies with phone-in advice and return to the Laboratory when necessary. This staffing approach continues but we rearranged our staffing patterns so that we now have one cryogenics engineer working a shift pattern which includes 8-hour daily coverage during the weekend. ATLAS provided a beam mix to users consisting of 26 different isotopic species, 23% of which were for A>100 in FY 1994. Approximately 60% of the beam time was provided by the Positive Ion Injector, slightly less than the usage rate of FY 1993. Experiments using uranium or lead beams accounted for 16.4% of the total beam time. The ECR ion source and high-voltage platform functioned well throughout the year. A new technique for solid material production in the source was developed which uses a sputtering process wherein the sample of material placed near the plasma chamber wall is biased negatively. Plasma ions are accelerated into the sample and material is sputtered from the surface into the plasma. This technique is now used routinely for many elements. Runs of calcium, germanium, nickel, lead, tellurium, and uranium were carried out with this technique.

  13. Accelerating DSMC data extraction.

    Energy Technology Data Exchange (ETDEWEB)

    Gallis, Michail A.; Piekos, Edward Stanley

    2006-10-01

    In many direct simulation Monte Carlo (DSMC) simulations, the majority of computation time is consumed after the flowfield reaches a steady state. This situation occurs when the desired output quantities are small compared to the background fluctuations. For example, gas flows in many microelectromechanical systems (MEMS) have mean speeds more than two orders of magnitude smaller than the thermal speeds of the molecules themselves. The current solution to this problem is to collect sufficient samples to achieve the desired resolution. This can be an arduous process because the error is inversely proportional to the square root of the number of samples so we must, for example, quadruple the samples to cut the error in half. This work is intended to improve this situation by employing more advanced techniques, from fields other than solely statistics, for determining the output quantities. Our strategy centers on exploiting information neglected by current techniques, which collect moments in each cell without regard to one another, values in neighboring cells, nor their evolution in time. Unlike many previous acceleration techniques that modify the method itself, the techniques examined in this work strictly post-process so they may be applied to any DSMC code without affecting its fidelity or generality. Many potential methods are drawn from successful applications in a diverse range of areas, from ultrasound imaging to financial market analysis. The most promising methods exploit relationships between variables in space, which always exist in DSMC due to the absence of shocks. Disparate techniques were shown to produce similar error reductions, suggesting that the results shown in this report may be typical of what is possible using these methods. Sample count reduction factors of approximately three to five were found to be typical, although factors exceeding ten were shown on some variables under some techniques.

  14. Accelerated coffee pulp composting.

    Science.gov (United States)

    Sánchez, G; Olguín, E J; Mercado, G

    1999-02-01

    The effect of two abundant, easily available and very low-cost agro-industrial organic residues, i.e., filter cake from the sugar industry and poultry litter, on the composting stabilization time of coffee pulp and on the quality of the produced compost, was evaluated. Piles of one cubic meter were built and monitored within the facilities of a coffee processing plant in the Coatepec region of the State of Veracruz, Mexico. Manual aeration was carried out once a week. A longer thermophilic period (28 days) and a much lower C/N ratio (in the range of 6.9-9.1) were observed in the piles containing the amendments, as compared to the control pile containing only coffee pulp (14 days and a C/N ratio of 14.4, respectively). The maximum assimilation rate of the reducing sugars was 1.6 g kg-1 d-1 (from 7.5 to 5.3%) during the first two weeks when accelerators were present in the proportion of 20% filter cake plus 20% poultry litter, while they accumulated at a rate of 1.2 g kg-1 d-1 (from 7.4 to 9.13%) during the same period in the control pile. The best combination of amendments was 30% filter cake with 20% poultry litter, resulting in a final nitrogen content as high as 4.81%. The second best combination was 20% filter cake with 10% poultry litter, resulting in a compost which also contained a high level of total nitrogen (4.54%). It was concluded that the use of these two residues enhanced the composting process of coffee pulp, promoting a shorter stabilization period and yielding a higher quality of compost.

  15. "small ACCELERATORS" 24 May - 2 June 2005

    CERN Multimedia

    2005-01-01

    CERN Accelerator School and Kernfysisch Versneller Instituut (KVI) Groningen, the Netherlands announce a course on "Small Accelerators", Hotel Golden Tulip Drenthe, Zeegse, the Netherlands, 24 May - 2 June 2005. This specialised course is dedicated to the physics and the main applications of small accelerators. The course will review the different accelerator types as well as their specificities in terms of accelerator physics.

  16. Führung und Zusammenarbeit am Lehrbereich Allgemeinmedizin der LMU München: Trotz erschwerter Bedingungen gute Noten [Leadership and cooperation at the general medicine department of LMU Munich: Good grades despite difficult conditions

    Directory of Open Access Journals (Sweden)

    Schelling, Jörg

    2011-11-01

    Full Text Available [english] The relevance of general medicine at German universities will increase over the next few years. Consequently, the discussion of teaching content and even more the improvement of the structures within the still small and dependent departments of general medicine are of major importance. The example of our department at LMU Munich shows which challenges for leadership and cooperation result from lack of financial and personnel structure. The project “cooperation culture” that the department has conducted in collaboration with the LMU Center for Leadership and People Management is presented as a means to promote leadership and cooperation. This project can serve as an inspiration for the coordinators of smaller departments of general medicine at other German universities that are also striving to improve their structure and their position within the university.[german] Die Bedeutung der Allgemeinmedizin an deutschen Universitäten wird in den nächsten Jahren weiter zunehmen. Umso wichtiger ist die Auseinandersetzung mit Lehrinhalten, aber auch die Verbesserung der Strukturen an den noch nicht ausgebauten Lehrbereichen für Allgemeinmedizin. Am Beispiel des Lehrbereichs Allgemeinmedizin der LMU München wird aufgezeigt, welche Herausforderungen der Führung und Zusammenarbeit aus Mangel an finanziellen und personellen Strukturen resultieren. Das Projekt „Zusammenarbeitskultur“, das der Lehrbereich in Kooperation mit dem LMU Center for Leadership and People Management durchgeführt hat, wird als Maßnahme zur Förderung von Führung und Zusammenarbeit vorgestellt. Dieses Projekt kann als Anregung für die Lehrkoordinatoren der kleineren Bereiche für Allgemeinmedizin anderer deutscher Universitäten dienen, die ebenfalls bestrebt sind, ihre Struktur sowie die Stellung innerhalb der Universität zu verbessern.

  17. Proton Acceleration at Oblique Shocks

    Science.gov (United States)

    Galinsky, V. L.; Shevchenko, V. I.

    2011-06-01

    Acceleration at the shock waves propagating oblique to the magnetic field is studied using a recently developed theoretical/numerical model. The model assumes that resonant hydromagnetic wave-particle interaction is the most important physical mechanism relevant to motion and acceleration of particles as well as to excitation and damping of waves. The treatment of plasma and waves is self-consistent and time dependent. The model uses conservation laws and resonance conditions to find where waves will be generated or damped, and hence particles will be pitch-angle-scattered. The total distribution is included in the model and neither introduction of separate population of seed particles nor some ad hoc escape rate of accelerated particles is needed. Results of the study show agreement with diffusive shock acceleration models in the prediction of power spectra for accelerated particles in the upstream region. However, they also reveal the presence of spectral break in the high-energy part of the spectra. The role of the second-order Fermi-like acceleration at the initial stage of the acceleration is discussed. The test case used in the paper is based on ISEE-3 data collected for the shock of 1978 November 12.

  18. Application of electron accelerator worldwide

    Energy Technology Data Exchange (ETDEWEB)

    Machi, Sueo [Japan Atomic Industrial Forum, Inc., Tokyo (Japan)

    2003-02-01

    Electron accelerator is an important radiation source for radiation technology, which covers broad fields such as industry, health care, food and environmental protection. There are about 1,000 electron accelerators for radiation processing worldwide. Electron accelerator has advantage over Co-60 irradiator in term of high dose rate and power, assurance of safety, and higher economic performance at larger volume of irradiation. Accelerator generating higher energy in the range of 10 MeV and high power electron beam is now commercially available. There is a trend to use high-energy electron accelerator replacing Co-60 in case of large through-put of medical products. Irradiated foods, in particular species, are on the commercial market in 35 countries. Electron accelerator is used efficiently and economically for production of new or modified polymeric materials through radiation-induced cross-linking, grafting and polymerization reaction. Another important application of electron beam is the curing of surface coatings in the manufacture of products. Electron accelerators of large capacity are used for cleaning exhaust gases in industrial scale. Economic feasibility studies of this electron beam process have shown that this technology is more cost effective than the conventional process. It should be noted that the conventional limestone process produce gypsum as a by-product, which cannot be used in some countries. By contrast, the by-product of the electron beam process is a valuable fertilizer. (Y. Tanaka)

  19. 2014 CERN Accelerator Schools: Beam Loss and Accelerator Protection

    CERN Multimedia

    2014-01-01

    The US-CERN-JAPAN-RUSSIA Joint International Accelerator School is organising a course on Beam Loss and Accelerator Protection to be held in Newport Beach, California, USA from 5-14 November, 2014.    This school is intended for physicists and engineers who are or may be engaged in the design, construction, and/or operation of accelerators with high power photon or particle beams and/or accelerator sub-systems with large stored energy. Application deadlines are 15 August and 4 September. Further information on this Joint School can be found at: http://cas.web.cern.ch/cas/JAS/Newport%20Beach%202014/NPBadvert.html http://indico.cern.ch/event/287647/ http://uspas.fnal.gov/programs/JAS/JAS14.shtml

  20. Utilizing a novel tandem oral dosing strategy to enhance exposure of low-solubility drug candidates in a preclinical setting.

    Science.gov (United States)

    Chiang, Po-Chang; South, Sarah A; Foster, Kimberly A; Daniels, J Scott; Wene, Steve P; Albin, Lesley A; Thompson, David C

    2010-07-01

    Time and resource constraints necessitate increasingly early decision making to accelerate or stop preclinical drug discovery programs. Early discovery drug candidates may be potent inhibitors of new targets, but all too often exhibit poor pharmaceutical and pharmacokinetic properties that limit the in vivo exposure. Low solubility of a drug candidate often leads to poor oral bioavailability and poor dose linearity that creates an issue for efficacy and target safety studies, where high drug exposures are desired. When solubility issues are encountered, enabling formulations are often used to improve the exposure. However, this approach often requires a substantial and lengthy investment to develop the formulation. In our study, two drug candidates with poor aqueous solubility were dosed in rats as simple suspension formulations using a novel tandem dosing strategy, which employs dosing orally in 2.5 h increments up to three times to simulate an oral infusion by avoiding saturation of absorption associated with bolus dosing. These compounds were also dosed using the same suspension formulations and a standard dosing strategy. The resulting in vivo exposures were compared. It was found that this novel tandem dosing strategy significantly improved the in vivo exposures.