WorldWideScience

Sample records for multiple design points

  1. Parallel point-multiplication architecture using combined group operations for high-speed cryptographic applications.

    Directory of Open Access Journals (Sweden)

    Md Selim Hossain

    Full Text Available In this paper, we propose a novel parallel architecture for fast hardware implementation of elliptic curve point multiplication (ECPM, which is the key operation of an elliptic curve cryptography processor. The point multiplication over binary fields is synthesized on both FPGA and ASIC technology by designing fast elliptic curve group operations in Jacobian projective coordinates. A novel combined point doubling and point addition (PDPA architecture is proposed for group operations to achieve high speed and low hardware requirements for ECPM. It has been implemented over the binary field which is recommended by the National Institute of Standards and Technology (NIST. The proposed ECPM supports two Koblitz and random curves for the key sizes 233 and 163 bits. For group operations, a finite-field arithmetic operation, e.g. multiplication, is designed on a polynomial basis. The delay of a 233-bit point multiplication is only 3.05 and 3.56 μs, in a Xilinx Virtex-7 FPGA, for Koblitz and random curves, respectively, and 0.81 μs in an ASIC 65-nm technology, which are the fastest hardware implementation results reported in the literature to date. In addition, a 163-bit point multiplication is also implemented in FPGA and ASIC for fair comparison which takes around 0.33 and 0.46 μs, respectively. The area-time product of the proposed point multiplication is very low compared to similar designs. The performance ([Formula: see text] and Area × Time × Energy (ATE product of the proposed design are far better than the most significant studies found in the literature.

  2. FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants.

    Science.gov (United States)

    Bednar, David; Beerens, Koen; Sebestova, Eva; Bendl, Jaroslav; Khare, Sagar; Chaloupkova, Radka; Prokop, Zbynek; Brezovsky, Jan; Baker, David; Damborsky, Jiri

    2015-11-01

    There is great interest in increasing proteins' stability to enhance their utility as biocatalysts, therapeutics, diagnostics and nanomaterials. Directed evolution is a powerful, but experimentally strenuous approach. Computational methods offer attractive alternatives. However, due to the limited reliability of predictions and potentially antagonistic effects of substitutions, only single-point mutations are usually predicted in silico, experimentally verified and then recombined in multiple-point mutants. Thus, substantial screening is still required. Here we present FireProt, a robust computational strategy for predicting highly stable multiple-point mutants that combines energy- and evolution-based approaches with smart filtering to identify additive stabilizing mutations. FireProt's reliability and applicability was demonstrated by validating its predictions against 656 mutations from the ProTherm database. We demonstrate that thermostability of the model enzymes haloalkane dehalogenase DhaA and γ-hexachlorocyclohexane dehydrochlorinase LinA can be substantially increased (ΔTm = 24°C and 21°C) by constructing and characterizing only a handful of multiple-point mutants. FireProt can be applied to any protein for which a tertiary structure and homologous sequences are available, and will facilitate the rapid development of robust proteins for biomedical and biotechnological applications.

  3. FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants.

    Directory of Open Access Journals (Sweden)

    David Bednar

    2015-11-01

    Full Text Available There is great interest in increasing proteins' stability to enhance their utility as biocatalysts, therapeutics, diagnostics and nanomaterials. Directed evolution is a powerful, but experimentally strenuous approach. Computational methods offer attractive alternatives. However, due to the limited reliability of predictions and potentially antagonistic effects of substitutions, only single-point mutations are usually predicted in silico, experimentally verified and then recombined in multiple-point mutants. Thus, substantial screening is still required. Here we present FireProt, a robust computational strategy for predicting highly stable multiple-point mutants that combines energy- and evolution-based approaches with smart filtering to identify additive stabilizing mutations. FireProt's reliability and applicability was demonstrated by validating its predictions against 656 mutations from the ProTherm database. We demonstrate that thermostability of the model enzymes haloalkane dehalogenase DhaA and γ-hexachlorocyclohexane dehydrochlorinase LinA can be substantially increased (ΔTm = 24°C and 21°C by constructing and characterizing only a handful of multiple-point mutants. FireProt can be applied to any protein for which a tertiary structure and homologous sequences are available, and will facilitate the rapid development of robust proteins for biomedical and biotechnological applications.

  4. Design and Integration of an All-Magnetic Attitude Control System for FASTSAT-HSV01's Multiple Pointing Objectives

    Science.gov (United States)

    DeKock, Brandon; Sanders, Devon; Vanzwieten, Tannen; Capo-Lugo, Pedro

    2011-01-01

    The FASTSAT-HSV01 spacecraft is a microsatellite with magnetic torque rods as it sole attitude control actuator. FASTSAT s multiple payloads and mission functions require the Attitude Control System (ACS) to maintain Local Vertical Local Horizontal (LVLH)-referenced attitudes without spin-stabilization, while the pointing errors for some attitudes be significantly smaller than the previous best-demonstrated for this type of control system. The mission requires the ACS to hold multiple stable, unstable, and non-equilibrium attitudes, as well as eject a 3U CubeSat from an onboard P-POD and recover from the ensuing tumble. This paper describes the Attitude Control System, the reasons for design choices, how the ACS integrates with the rest of the spacecraft, and gives recommendations for potential future applications of the work.

  5. On the design of a radix-10 online floating-point multiplier

    Science.gov (United States)

    McIlhenny, Robert D.; Ercegovac, Milos D.

    2009-08-01

    This paper describes an approach to design and implement a radix-10 online floating-point multiplier. An online approach is considered because it offers computational flexibility not available with conventional arithmetic. The design was coded in VHDL and compiled, synthesized, and mapped onto a Virtex 5 FPGA to measure cost in terms of LUTs (look-up-tables) as well as the cycle time and total latency. The routing delay which was not optimized is the major component in the cycle time. For a rough estimate of the cost/latency characteristics, our design was compared to a standard radix-2 floating-point multiplier of equivalent precision. The results demonstrate that even an unoptimized radix-10 online design is an attractive implementation alternative for FPGA floating-point multiplication.

  6. Beginning SharePoint Designer 2010

    CERN Document Server

    Windischman, Woodrow W; Rehmani, Asif

    2010-01-01

    Teaching Web designers, developers, and IT professionals how to use the new version of SharePoint Designer. Covering both the design and business applications of SharePoint Designer, this complete Wrox guide brings readers thoroughly up to speed on how to use SharePoint Designer in an enterprise. You'll learn to create and modify web pages, use CSS editing tools to modify themes, use Data View to create interactivity with SharePoint and other data, and much more. Coverage includes integration points with Visual Studio, Visio, and InfoPath.: Shows web designers, developers, and IT professionals

  7. Multiplicity: discussion points from the Statisticians in the Pharmaceutical Industry multiplicity expert group.

    Science.gov (United States)

    Phillips, Alan; Fletcher, Chrissie; Atkinson, Gary; Channon, Eddie; Douiri, Abdel; Jaki, Thomas; Maca, Jeff; Morgan, David; Roger, James Henry; Terrill, Paul

    2013-01-01

    In May 2012, the Committee of Health and Medicinal Products issued a concept paper on the need to review the points to consider document on multiplicity issues in clinical trials. In preparation for the release of the updated guidance document, Statisticians in the Pharmaceutical Industry held a one-day expert group meeting in January 2013. Topics debated included multiplicity and the drug development process, the usefulness and limitations of newly developed strategies to deal with multiplicity, multiplicity issues arising from interim decisions and multiregional development, and the need for simultaneous confidence intervals (CIs) corresponding to multiple test procedures. A clear message from the meeting was that multiplicity adjustments need to be considered when the intention is to make a formal statement about efficacy or safety based on hypothesis tests. Statisticians have a key role when designing studies to assess what adjustment really means in the context of the research being conducted. More thought during the planning phase needs to be given to multiplicity adjustments for secondary endpoints given these are increasing in importance in differentiating products in the market place. No consensus was reached on the role of simultaneous CIs in the context of superiority trials. It was argued that unadjusted intervals should be employed as the primary purpose of the intervals is estimation, while the purpose of hypothesis testing is to formally establish an effect. The opposing view was that CIs should correspond to the test decision whenever possible. Copyright © 2013 John Wiley & Sons, Ltd.

  8. Supporting Multiple Pointing Devices in Microsoft Windows

    DEFF Research Database (Denmark)

    Westergaard, Michael

    2002-01-01

    In this paper the implementation of a Microsoft Windows driver including APIs supporting multiple pointing devices is presented. Microsoft Windows does not natively support multiple pointing devices controlling independent cursors, and a number of solutions to this have been implemented by us and...... and others. Here we motivate and describe a general solution, and how user applications can use it by means of a framework. The device driver and the supporting APIs will be made available free of charge. Interested parties can contact the author for more information....

  9. History Matching Through a Smooth Formulation of Multiple-Point Statistics

    DEFF Research Database (Denmark)

    Melnikova, Yulia; Zunino, Andrea; Lange, Katrine

    2014-01-01

    and the mismatch with multiple-point statistics. As a result, in the framework of the Bayesian approach, such a solution belongs to a high posterior region. The methodology, while applicable to any inverse problem with a training-image-based prior, is especially beneficial for problems which require expensive......We propose a smooth formulation of multiple-point statistics that enables us to solve inverse problems using gradient-based optimization techniques. We introduce a differentiable function that quantifies the mismatch between multiple-point statistics of a training image and of a given model. We...... show that, by minimizing this function, any continuous image can be gradually transformed into an image that honors the multiple-point statistics of the discrete training image. The solution to an inverse problem is then found by minimizing the sum of two mismatches: the mismatch with data...

  10. Multi-lane detection based on multiple vanishing points detection

    Science.gov (United States)

    Li, Chuanxiang; Nie, Yiming; Dai, Bin; Wu, Tao

    2015-03-01

    Lane detection plays a significant role in Advanced Driver Assistance Systems (ADAS) for intelligent vehicles. In this paper we present a multi-lane detection method based on multiple vanishing points detection. A new multi-lane model assumes that a single lane, which has two approximately parallel boundaries, may not parallel to others on road plane. Non-parallel lanes associate with different vanishing points. A biological plausibility model is used to detect multiple vanishing points and fit lane model. Experimental results show that the proposed method can detect both parallel lanes and non-parallel lanes.

  11. Evaluation of multiple emission point facilities

    International Nuclear Information System (INIS)

    Miltenberger, R.P.; Hull, A.P.; Strachan, S.; Tichler, J.

    1988-01-01

    In 1970, the New York State Department of Environmental Conservation (NYSDEC) assumed responsibility for the environmental aspect of the state's regulatory program for by-product, source, and special nuclear material. The major objective of this study was to provide consultation to NYSDEC and the US NRC to assist NYSDEC in determining if broad-based licensed facilities with multiple emission points were in compliance with NYCRR Part 380. Under this contract, BNL would evaluate a multiple emission point facility, identified by NYSDEC, as a case study. The review would be a nonbinding evaluation of the facility to determine likely dispersion characteristics, compliance with specified release limits, and implementation of the ALARA philosophy regarding effluent release practices. From the data collected, guidance as to areas of future investigation and the impact of new federal regulations were to be developed. Reported here is the case study for the University of Rochester, Strong Memorial Medical Center and Riverside Campus

  12. EBTR design-point selection

    International Nuclear Information System (INIS)

    Krakowski, R.A.; Bathke, C.G.

    1981-01-01

    The procedure used to select the design point for the ELMO Bumpy Torus Reactor (EBTR) study is described. The models used in each phase of the selection process are described, with an emphasis placed on the parametric design curves produced by each model. The tradeoffs related to burn physics, stability/equilibrium, electron-ring physics, and magnetics design are discussed. The resulting design point indicates a plasma with a 35-m major radius and a 1-m minor radium operating at an average core-plasma beta of 0.17, which at approx. 30 keV produces an average neutron wall loading of 1.4 MW/m 2 while maintaining key magnet (< 10 T) and total power (less than or equal to 4000 MWt) constraints

  13. A MOSUM procedure for the estimation of multiple random change points

    OpenAIRE

    Eichinger, Birte; Kirch, Claudia

    2018-01-01

    In this work, we investigate statistical properties of change point estimators based on moving sum statistics. We extend results for testing in a classical situation with multiple deterministic change points by allowing for random exogenous change points that arise in Hidden Markov or regime switching models among others. To this end, we consider a multiple mean change model with possible time series errors and prove that the number and location of change points are estimated consistently by ...

  14. MULTIPLE ACCESS POINTS WITHIN THE ONLINE CLASSROOM: WHERE STUDENTS LOOK FOR INFORMATION

    Directory of Open Access Journals (Sweden)

    John STEELE

    2017-01-01

    Full Text Available The purpose of this study is to examine the impact of information placement within the confines of the online classroom architecture. Also reviewed was the impact of other variables such as course design, teaching presence and student patterns in looking for information. The sample population included students from a major online university in their first year course sequence. Students were tasked with completing a survey at the end of the course, indicating their preference for accessing information within the online classroom. The qualitative data indicated that student preference is to receive information from multiple access points and sources within the online classroom architecture. Students also expressed a desire to have information delivered through the usage of technology such as email and text messaging. In addition to receiving information from multiple sources, the qualitative data indicated students were satisfied overall, with the current ways in which they received and accessed information within the online classroom setting. Major findings suggest that instructors teaching within the online classroom should have multiple data access points within the classroom architecture. Furthermore, instructors should use a variety of communication venues to enhance the ability for students to access and receive information pertinent to the course.

  15. Tripled Fixed Point in Ordered Multiplicative Metric Spaces

    Directory of Open Access Journals (Sweden)

    Laishram Shanjit

    2017-06-01

    Full Text Available In this paper, we present some triple fixed point theorems in partially ordered multiplicative metric spaces depended on another function. Our results generalise the results of [6] and [5].

  16. Reduction of bias in neutron multiplicity assay using a weighted point model

    Energy Technology Data Exchange (ETDEWEB)

    Geist, W. H. (William H.); Krick, M. S. (Merlyn S.); Mayo, D. R. (Douglas R.)

    2004-01-01

    Accurate assay of most common plutonium samples was the development goal for the nondestructive assay technique of neutron multiplicity counting. Over the past 20 years the technique has been proven for relatively pure oxides and small metal items. Unfortunately, the technique results in large biases when assaying large metal items. Limiting assumptions, such as unifoh multiplication, in the point model used to derive the multiplicity equations causes these biases for large dense items. A weighted point model has been developed to overcome some of the limitations in the standard point model. Weighting factors are detemiined from Monte Carlo calculations using the MCNPX code. Monte Carlo calculations give the dependence of the weighting factors on sample mass and geometry, and simulated assays using Monte Carlo give the theoretical accuracy of the weighted-point-model assay. Measured multiplicity data evaluated with both the standard and weighted point models are compared to reference values to give the experimental accuracy of the assay. Initial results show significant promise for the weighted point model in reducing or eliminating biases in the neutron multiplicity assay of metal items. The negative biases observed in the assay of plutonium metal samples are caused by variations in the neutron multiplication for neutrons originating in various locations in the sample. The bias depends on the mass and shape of the sample and depends on the amount and energy distribution of the ({alpha},n) neutrons in the sample. When the standard point model is used, this variable-multiplication bias overestimates the multiplication and alpha values of the sample, and underestimates the plutonium mass. The weighted point model potentially can provide assay accuracy of {approx}2% (1 {sigma}) for cylindrical plutonium metal samples < 4 kg with {alpha} < 1 without knowing the exact shape of the samples, provided that the ({alpha},n) source is uniformly distributed throughout the

  17. Parametric Architectural Design with Point-clouds

    DEFF Research Database (Denmark)

    Zwierzycki, Mateusz; Evers, Henrik Leander; Tamke, Martin

    2016-01-01

    This paper investigates the efforts and benefits of the implementation of point clouds into architectural design processes and tools. Based on a study on the principal work processes of designers with point clouds the prototypical plugin/library - Volvox - was developed for the parametric modelling...

  18. Photonic crystals possessing multiple Weyl points and the experimental observation of robust surface states

    Science.gov (United States)

    Chen, Wen-Jie; Xiao, Meng; Chan, C. T.

    2016-01-01

    Weyl points, as monopoles of Berry curvature in momentum space, have captured much attention recently in various branches of physics. Realizing topological materials that exhibit such nodal points is challenging and indeed, Weyl points have been found experimentally in transition metal arsenide and phosphide and gyroid photonic crystal whose structure is complex. If realizing even the simplest type of single Weyl nodes with a topological charge of 1 is difficult, then making a real crystal carrying higher topological charges may seem more challenging. Here we design, and fabricate using planar fabrication technology, a photonic crystal possessing single Weyl points (including type-II nodes) and multiple Weyl points with topological charges of 2 and 3. We characterize this photonic crystal and find nontrivial 2D bulk band gaps for a fixed kz and the associated surface modes. The robustness of these surface states against kz-preserving scattering is experimentally observed for the first time. PMID:27703140

  19. Designing a Secure Point-of-Sale System

    DEFF Research Database (Denmark)

    Sharp, Robin; Pedersen, Allan; Hedegaard, Anders

    2006-01-01

    This paper describes some experiences with using the ''Common Criteria for Information Security Evaluation'' as the basis for a design methodology when designing secure systems. As an example, the design process for a Point-of-Sale (POS) system is described.......This paper describes some experiences with using the ''Common Criteria for Information Security Evaluation'' as the basis for a design methodology when designing secure systems. As an example, the design process for a Point-of-Sale (POS) system is described....

  20. Design of the cooling systems for the multiplicity and vertex detector

    International Nuclear Information System (INIS)

    Bernardin, J.D.; Cunningham, R.

    1997-11-01

    The PHENIX experiment at the Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Laboratory is being constructed to investigate a phase of matter termed the quark-gluon plasma. The plasma will be produced through the collision of two heavy ions. The multiplicity and vertex detector (MVD) located in the center of PHENIX will characterize the events, determine the collision point, and act as a central trigger. This report presents the final mechanical designs of the cooling systems for the Multiplicity and Vertex Detector (MVD). In particular, the design procedure and layouts are discussed for two different air cooling systems for the multichip modules and MVD enclosure, and a liquid cooling system for the low dropout voltage regulators. First of all, experimental prototype cooling system test results used to drive the final mechanical designs are summarized and discussed. Next, the cooling system requirements and design calculation for the various subsystem components are presented along with detailed lists of supply vendors, components, and costs. Finally, safety measures incorporated in the final mechanical design and operation procedures for each of the subsystems are detailed

  1. Pilot points method for conditioning multiple-point statistical facies simulation on flow data

    Science.gov (United States)

    Ma, Wei; Jafarpour, Behnam

    2018-05-01

    We propose a new pilot points method for conditioning discrete multiple-point statistical (MPS) facies simulation on dynamic flow data. While conditioning MPS simulation on static hard data is straightforward, their calibration against nonlinear flow data is nontrivial. The proposed method generates conditional models from a conceptual model of geologic connectivity, known as a training image (TI), by strategically placing and estimating pilot points. To place pilot points, a score map is generated based on three sources of information: (i) the uncertainty in facies distribution, (ii) the model response sensitivity information, and (iii) the observed flow data. Once the pilot points are placed, the facies values at these points are inferred from production data and then are used, along with available hard data at well locations, to simulate a new set of conditional facies realizations. While facies estimation at the pilot points can be performed using different inversion algorithms, in this study the ensemble smoother (ES) is adopted to update permeability maps from production data, which are then used to statistically infer facies types at the pilot point locations. The developed method combines the information in the flow data and the TI by using the former to infer facies values at selected locations away from the wells and the latter to ensure consistent facies structure and connectivity where away from measurement locations. Several numerical experiments are used to evaluate the performance of the developed method and to discuss its important properties.

  2. Turning points in reactor design

    International Nuclear Information System (INIS)

    Beckjord, E.S.

    1995-01-01

    This article provides some historical aspects on nuclear reactor design, beginning with PWR development for Naval Propulsion and the first commercial application at Yankee Rowe. Five turning points in reactor design and some safety problems associated with them are reviewed: (1) stability of Dresden-1, (2) ECCS, (3) PRA, (4) TMI-2, and (5) advanced passive LWR designs. While the emphasis is on the thermal-hydraulic aspects, the discussion is also about reactor systems

  3. Turning points in reactor design

    Energy Technology Data Exchange (ETDEWEB)

    Beckjord, E.S.

    1995-09-01

    This article provides some historical aspects on nuclear reactor design, beginning with PWR development for Naval Propulsion and the first commercial application at Yankee Rowe. Five turning points in reactor design and some safety problems associated with them are reviewed: (1) stability of Dresden-1, (2) ECCS, (3) PRA, (4) TMI-2, and (5) advanced passive LWR designs. While the emphasis is on the thermal-hydraulic aspects, the discussion is also about reactor systems.

  4. Design of an omnidirectional single-point photodetector for large-scale spatial coordinate measurement

    Science.gov (United States)

    Xie, Hongbo; Mao, Chensheng; Ren, Yongjie; Zhu, Jigui; Wang, Chao; Yang, Lei

    2017-10-01

    In high precision and large-scale coordinate measurement, one commonly used approach to determine the coordinate of a target point is utilizing the spatial trigonometric relationships between multiple laser transmitter stations and the target point. A light receiving device at the target point is the key element in large-scale coordinate measurement systems. To ensure high-resolution and highly sensitive spatial coordinate measurement, a high-performance and miniaturized omnidirectional single-point photodetector (OSPD) is greatly desired. We report one design of OSPD using an aspheric lens, which achieves an enhanced reception angle of -5 deg to 45 deg in vertical and 360 deg in horizontal. As the heart of our OSPD, the aspheric lens is designed in a geometric model and optimized by LightTools Software, which enables the reflection of a wide-angle incident light beam into the single-point photodiode. The performance of home-made OSPD is characterized with working distances from 1 to 13 m and further analyzed utilizing developed a geometric model. The experimental and analytic results verify that our device is highly suitable for large-scale coordinate metrology. The developed device also holds great potential in various applications such as omnidirectional vision sensor, indoor global positioning system, and optical wireless communication systems.

  5. Common Fixed Points of Generalized Rational Type Cocyclic Mappings in Multiplicative Metric Spaces

    Directory of Open Access Journals (Sweden)

    Mujahid Abbas

    2015-01-01

    Full Text Available The aim of this paper is to present fixed point result of mappings satisfying a generalized rational contractive condition in the setup of multiplicative metric spaces. As an application, we obtain a common fixed point of a pair of weakly compatible mappings. Some common fixed point results of pair of rational contractive types mappings involved in cocyclic representation of a nonempty subset of a multiplicative metric space are also obtained. Some examples are presented to support the results proved herein. Our results generalize and extend various results in the existing literature.

  6. A Common Probe Design for Multiple Planetary Destinations

    Science.gov (United States)

    Hwang, H. H.; Allen, G. A., Jr.; Alunni, A. I.; Amato, M. J.; Atkinson, D. H.; Bienstock, B. J.; Cruz, J. R.; Dillman, R. A.; Cianciolo, A. D.; Elliott, J. O.; hide

    2018-01-01

    Atmospheric probes have been successfully flown to planets and moons in the solar system to conduct in situ measurements. They include the Pioneer Venus multi-probes, the Galileo Jupiter probe, and Huygens probe. Probe mission concepts to five destinations, including Venus, Jupiter, Saturn, Uranus, and Neptune, have all utilized similar-shaped aeroshells and concept of operations, namely a 45-degree sphere cone shape with high density heatshield material and parachute system for extracting the descent vehicle from the aeroshell. Each concept designed its probe to meet specific mission requirements and to optimize mass, volume, and cost. At the 2017 International Planetary Probe Workshop (IPPW), NASA Headquarters postulated that a common aeroshell design could be used successfully for multiple destinations and missions. This "common probe"� design could even be assembled with multiple copies, properly stored, and made available for future NASA missions, potentially realizing savings in cost and schedule and reducing the risk of losing technologies and skills difficult to sustain over decades. Thus the NASA Planetary Science Division funded a study to investigate whether a common probe design could meet most, if not all, mission needs to the five planetary destinations with extreme entry environments. The Common Probe study involved four NASA Centers and addressed these issues, including constraints and inefficiencies that occur in specifying a common design. Study methodology: First, a notional payload of instruments for each destination was defined based on priority measurements from the Planetary Science Decadal Survey. Steep and shallow entry flight path angles (EFPA) were defined for each planet based on qualification and operational g-load limits for current, state-of-the-art instruments. Interplanetary trajectories were then identified for a bounding range of EFPA. Next, 3-degrees-of-freedom simulations for entry trajectories were run using the entry state

  7. Use of multiple water surface flow constructed wetlands for non-point source water pollution control.

    Science.gov (United States)

    Li, Dan; Zheng, Binghui; Liu, Yan; Chu, Zhaosheng; He, Yan; Huang, Minsheng

    2018-05-02

    Multiple free water surface flow constructed wetlands (multi-FWS CWs) are a variety of conventional water treatment plants for the interception of pollutants. This review encapsulated the characteristics and applications in the field of ecological non-point source water pollution control technology. The roles of in-series design and operation parameters (hydraulic residence time, hydraulic load rate, water depth and aspect ratio, composition of influent, and plant species) for performance intensification were also analyzed, which were crucial to achieve sustainable and effective contaminants removal, especially the retention of nutrient. The mechanism study of design and operation parameters for the removal of nitrogen and phosphorus was also highlighted. Conducive perspectives for further research on optimizing its design/operation parameters and advanced technologies of ecological restoration were illustrated to possibly interpret the functions of multi-FWS CWs.

  8. Improving the Pattern Reproducibility of Multiple-Point-Based Prior Models Using Frequency Matching

    DEFF Research Database (Denmark)

    Cordua, Knud Skou; Hansen, Thomas Mejer; Mosegaard, Klaus

    2014-01-01

    Some multiple-point-based sampling algorithms, such as the snesim algorithm, rely on sequential simulation. The conditional probability distributions that are used for the simulation are based on statistics of multiple-point data events obtained from a training image. During the simulation, data...... events with zero probability in the training image statistics may occur. This is handled by pruning the set of conditioning data until an event with non-zero probability is found. The resulting probability distribution sampled by such algorithms is a pruned mixture model. The pruning strategy leads...... to a probability distribution that lacks some of the information provided by the multiple-point statistics from the training image, which reduces the reproducibility of the training image patterns in the outcome realizations. When pruned mixture models are used as prior models for inverse problems, local re...

  9. High-Temperature Gas-Cooled Test Reactor Point Design

    Energy Technology Data Exchange (ETDEWEB)

    Sterbentz, James William [Idaho National Laboratory; Bayless, Paul David [Idaho National Laboratory; Nelson, Lee Orville [Idaho National Laboratory; Gougar, Hans David [Idaho National Laboratory; Kinsey, James Carl [Idaho National Laboratory; Strydom, Gerhard [Idaho National Laboratory; Kumar, Akansha [Idaho National Laboratory

    2016-04-01

    A point design has been developed for a 200 MW high-temperature gas-cooled test reactor. The point design concept uses standard prismatic blocks and 15.5% enriched UCO fuel. Reactor physics and thermal-hydraulics simulations have been performed to characterize the capabilities of the design. In addition to the technical data, overviews are provided on the technological readiness level, licensing approach and costs.

  10. An Updated Point Design for Heavy Ion Fusion

    International Nuclear Information System (INIS)

    Yu, S.S.; Meier, W.R.; Abbott, R.B.; Barnard, J.J.; Brown, T.; Callahan, D.A.; Heitzenroeder, P.; Latkowski, J.F.; Logan, B.G.; Pemberton, S.J.; Peterson, P.F.; Rose, D.V.; Sabbi, G.L.; Sharp, W.M.; Welch, D.R.

    2002-01-01

    An updated, self-consistent point design for a heavy ion fusion (HIF) power plant based on an induction linac driver, indirect-drive targets, and a thick liquid wall chamber has been completed. Conservative parameters were selected to allow each design area to meet its functional requirements in a robust manner, and thus this design is referred to as the Robust Point Design (RPD-2002). This paper provides a top-level summary of the major characteristics and design parameters for the target, driver, final focus magnet layout and shielding, chamber, beam propagation to the target, and overall power plant

  11. Point spread function engineering for iris recognition system design.

    Science.gov (United States)

    Ashok, Amit; Neifeld, Mark A

    2010-04-01

    Undersampling in the detector array degrades the performance of iris-recognition imaging systems. We find that an undersampling of 8 x 8 reduces the iris-recognition performance by nearly a factor of 4 (on CASIA iris database), as measured by the false rejection ratio (FRR) metric. We employ optical point spread function (PSF) engineering via a Zernike phase mask in conjunction with multiple subpixel shifted image measurements (frames) to mitigate the effect of undersampling. A task-specific optimization framework is used to engineer the optical PSF and optimize the postprocessing parameters to minimize the FRR. The optimized Zernike phase enhanced lens (ZPEL) imager design with one frame yields an improvement of nearly 33% relative to a thin observation module by bounded optics (TOMBO) imager with one frame. With four frames the optimized ZPEL imager achieves a FRR equal to that of the conventional imager without undersampling. Further, the ZPEL imager design using 16 frames yields a FRR that is actually 15% lower than that obtained with the conventional imager without undersampling.

  12. Program computes single-point failures in critical system designs

    Science.gov (United States)

    Brown, W. R.

    1967-01-01

    Computer program analyzes the designs of critical systems that will either prove the design is free of single-point failures or detect each member of the population of single-point failures inherent in a system design. This program should find application in the checkout of redundant circuits and digital systems.

  13. Error analysis of dimensionless scaling experiments with multiple points using linear regression

    International Nuclear Information System (INIS)

    Guercan, Oe.D.; Vermare, L.; Hennequin, P.; Bourdelle, C.

    2010-01-01

    A general method of error estimation in the case of multiple point dimensionless scaling experiments, using linear regression and standard error propagation, is proposed. The method reduces to the previous result of Cordey (2009 Nucl. Fusion 49 052001) in the case of a two-point scan. On the other hand, if the points follow a linear trend, it explains how the estimated error decreases as more points are added to the scan. Based on the analytical expression that is derived, it is argued that for a low number of points, adding points to the ends of the scanned range, rather than the middle, results in a smaller error estimate. (letter)

  14. Mirrored pyramidal wells for simultaneous multiple vantage point microscopy.

    Science.gov (United States)

    Seale, K T; Reiserer, R S; Markov, D A; Ges, I A; Wright, C; Janetopoulos, C; Wikswo, J P

    2008-10-01

    We report a novel method for obtaining simultaneous images from multiple vantage points of a microscopic specimen using size-matched microscopic mirrors created from anisotropically etched silicon. The resulting pyramidal wells enable bright-field and fluorescent side-view images, and when combined with z-sectioning, provide additional information for 3D reconstructions of the specimen. We have demonstrated the 3D localization and tracking over time of the centrosome of a live Dictyostelium discoideum. The simultaneous acquisition of images from multiple perspectives also provides a five-fold increase in the theoretical collection efficiency of emitted photons, a property which may be useful for low-light imaging modalities such as bioluminescence, or low abundance surface-marker labelling.

  15. High Temperature Gas-Cooled Test Reactor Point Design: Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Sterbentz, James William [Idaho National Lab. (INL), Idaho Falls, ID (United States); Bayless, Paul David [Idaho National Lab. (INL), Idaho Falls, ID (United States); Nelson, Lee Orville [Idaho National Lab. (INL), Idaho Falls, ID (United States); Gougar, Hans David [Idaho National Lab. (INL), Idaho Falls, ID (United States); Kinsey, J. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Strydom, Gerhard [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-03-01

    A point design has been developed for a 200-MW high-temperature gas-cooled test reactor. The point design concept uses standard prismatic blocks and 15.5% enriched uranium oxycarbide fuel. Reactor physics and thermal-hydraulics simulations have been performed to characterize the capabilities of the design. In addition to the technical data, overviews are provided on the technology readiness level, licensing approach, and costs of the test reactor point design.

  16. High Temperature Gas-Cooled Test Reactor Point Design: Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Sterbentz, James William [Idaho National Lab. (INL), Idaho Falls, ID (United States); Bayless, Paul David [Idaho National Lab. (INL), Idaho Falls, ID (United States); Nelson, Lee Orville [Idaho National Lab. (INL), Idaho Falls, ID (United States); Gougar, Hans David [Idaho National Lab. (INL), Idaho Falls, ID (United States); Strydom, Gerhard [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-01-01

    A point design has been developed for a 200-MW high-temperature gas-cooled test reactor. The point design concept uses standard prismatic blocks and 15.5% enriched uranium oxycarbide fuel. Reactor physics and thermal-hydraulics simulations have been performed to characterize the capabilities of the design. In addition to the technical data, overviews are provided on the technology readiness level, licensing approach, and costs of the test reactor point design.

  17. Variogram based and Multiple - Point Statistical simulation of shallow aquifer structures in the Upper Salzach valley, Austria

    Science.gov (United States)

    Jandrisevits, Carmen; Marschallinger, Robert

    2014-05-01

    /erosional processes and geometric shapes of hydrofacies can be integrated. The Training Image can be constructed with object based Training Image generators which offer predefined geometric shapes for modeling sediment facies associations. Training Images can also be constructed in a Computer Aided Design (CAD) system. Non-uniform rational B-Splines are implemented in CAD systems and enable to generate even more realistic geometric shapes of sediment bodies than by means of object based training image generators. Multiple Point Statistics Simulation aims to produce local patterns from the Training Image and conditionally anchor them to the investigation data. Regarding geometric shapes and lateral extensions of derived sediment structures, the Multiple Point Statistics simulations yielded the most sensible hydrofacies models while reproducing input data proportions.

  18. A feature point identification method for positron emission particle tracking with multiple tracers

    Energy Technology Data Exchange (ETDEWEB)

    Wiggins, Cody, E-mail: cwiggin2@vols.utk.edu [University of Tennessee-Knoxville, Department of Physics and Astronomy, 1408 Circle Drive, Knoxville, TN 37996 (United States); Santos, Roque [University of Tennessee-Knoxville, Department of Nuclear Engineering (United States); Escuela Politécnica Nacional, Departamento de Ciencias Nucleares (Ecuador); Ruggles, Arthur [University of Tennessee-Knoxville, Department of Nuclear Engineering (United States)

    2017-01-21

    A novel detection algorithm for Positron Emission Particle Tracking (PEPT) with multiple tracers based on optical feature point identification (FPI) methods is presented. This new method, the FPI method, is compared to a previous multiple PEPT method via analyses of experimental and simulated data. The FPI method outperforms the older method in cases of large particle numbers and fine time resolution. Simulated data show the FPI method to be capable of identifying 100 particles at 0.5 mm average spatial error. Detection error is seen to vary with the inverse square root of the number of lines of response (LORs) used for detection and increases as particle separation decreases. - Highlights: • A new approach to positron emission particle tracking is presented. • Using optical feature point identification analogs, multiple particle tracking is achieved. • Method is compared to previous multiple particle method. • Accuracy and applicability of method is explored.

  19. Accuracy Constraint Determination in Fixed-Point System Design

    Directory of Open Access Journals (Sweden)

    Serizel R

    2008-01-01

    Full Text Available Most of digital signal processing applications are specified and designed with floatingpoint arithmetic but are finally implemented using fixed-point architectures. Thus, the design flow requires a floating-point to fixed-point conversion stage which optimizes the implementation cost under execution time and accuracy constraints. This accuracy constraint is linked to the application performances and the determination of this constraint is one of the key issues of the conversion process. In this paper, a method is proposed to determine the accuracy constraint from the application performance. The fixed-point system is modeled with an infinite precision version of the system and a single noise source located at the system output. Then, an iterative approach for optimizing the fixed-point specification under the application performance constraint is defined and detailed. Finally the efficiency of our approach is demonstrated by experiments on an MP3 encoder.

  20. Preliminary A ampersand PCT multiple detector design

    International Nuclear Information System (INIS)

    Roberson, G.P.; Martz, H.E.; Camp, D.C.; Decman, D.J.; Johansson, E.M.

    1997-01-01

    The next generation, multi-detector active and passive computed tomography (A ampersand PCT) scanner will be optimized for speed and accuracy. At the Lawrence Livermore National Lab (LLNL) we have demonstrated the trade-offs between different A ampersand PCT design parameters that affect the speed and quality of the assay results. These fundamental parameters govern the optimum system design. Although the multi-detector scanner design has priority put on speed to increase waste drum throughput, higher speed should not compromise assay accuracy. One way to increase the speed of the A ampersand PCT technology is to use multiple detectors. This yields a linear speedup by a factor approximately equal to the number of detectors used without a compromise in system accuracy. There are many different design scenarios that can be developed using multiple detectors. Here we describe four different scenarios and discuss the trade-offs between them. Also, some considerations are given in this design description for the implementation of a multiple detector technology in a field- deployable mobile trailer system

  1. Multiple-valued logic design based on the multiple-peak BiCMOS-NDR circuits

    Directory of Open Access Journals (Sweden)

    Kwang-Jow Gan

    2016-06-01

    Full Text Available Three different multiple-valued logic (MVL designs using the multiple-peak negative-differential-resistance (NDR circuits are investigated. The basic NDR element, which is made of several Si-based metal-oxide-semiconductor field-effect-transistor (MOS and SiGe-based heterojunction-bipolar-transistor (HBT devices, can be implemented by using a standard BiCMOS process. These MVL circuits are designed based on the triggering-pulse control, saw-tooth input signal, and peak-control methods, respectively. However, there are some transient states existing between the multiple stable levels for the first two methods. These states might affect the circuit function in practical application. As a result, our proposed peak-control method for the MVL design can be used to overcome these transient states.

  2. Preferred design of transfer points

    Energy Technology Data Exchange (ETDEWEB)

    Firstbrook, J

    1983-06-01

    The paper reports the results of a study carried out at MRDE on the performance of transfer points. These sites still require a considerable deployment of manpower. The investigations were divided into 3 main sections: mineral handling; chute design; belt cleaning and spillage conveying. In order to achieve a sufficient level of reliability of a transfer system, it is considered that the coal size should not be greater than 250 mm. Different designs of gravity transfer chute were studied and 3 basic designs emerged as being effective : dump chute, curved site entry, and asymmetric side entry. Selection is dependent on conveyor sizes, speeds, and mineral throughput. Individual belt cleaners are not sufficient to clean belts carrying typical run-of-mine material: two cleaners followed by a set of squeeze rollers are recommended. Several designs of spillage conveyor were investigated; at the present time the electro/hydraulic type appears to be the most satisfactory.

  3. Evidence-based point-of-care tests and device designs for disaster preparedness.

    Science.gov (United States)

    Brock, T Keith; Mecozzi, Daniel M; Sumner, Stephanie; Kost, Gerald J

    2010-01-01

    To define pathogen tests and device specifications needed for emerging point-of-care (POC) technologies used in disasters. Surveys included multiple-choice and ranking questions. Multiple-choice questions were analyzed with the chi2 test for goodness-of-fit and the binomial distribution test. Rankings were scored and compared using analysis of variance and Tukey's multiple comparison test. Disaster care experts on the editorial boards of the American Journal of Disaster Medicine and the Disaster Medicine and Public Health Preparedness, and the readers of the POC Journal. Vibrio cholera and Staphylococcus aureus were top-ranked pathogens for testing in disaster settings. Respondents felt that disaster response teams should be equipped with pandemic infectious disease tests for novel 2009 H1N1 and avian H5N1 influenza (disaster care, p disaster settings, respondents preferred self-contained test cassettes (disaster care, p disaster care, p disaster care scenarios, in which Vibrio cholera, methicillin-sensitive and methicillin-resistant Staphylococcus aureus, and Escherichia coli ranked the highest. POC testing should incorporate setting-specific design criteria such as safe disposable cassettes and direct blood sampling at the site of care.

  4. Determination of shell correction energies at saddle point using pre-scission neutron multiplicities

    International Nuclear Information System (INIS)

    Golda, K.S.; Saxena, A.; Mittal, V.K.; Mahata, K.; Sugathan, P.; Jhingan, A.; Singh, V.; Sandal, R.; Goyal, S.; Gehlot, J.; Dhal, A.; Behera, B.R.; Bhowmik, R.K.; Kailas, S.

    2013-01-01

    Pre-scission neutron multiplicities have been measured for 12 C + 194, 198 Pt systems at matching excitation energies at near Coulomb barrier region. Statistical model analysis with a modified fission barrier and level density prescription have been carried out to fit the measured pre-scission neutron multiplicities and the available evaporation residue and fission cross sections simultaneously to constrain statistical model parameters. Simultaneous fitting of the pre-scission neutron multiplicities and cross section data requires shell correction at the saddle point

  5. A 34-meter VAWT (Vertical Axis Wind Turbine) point design

    Science.gov (United States)

    Ashwill, T. D.; Berg, D. E.; Dodd, H. M.; Rumsey, M. A.; Sutherland, H. J.; Veers, P. S.

    The Wind Energy Division at Sandia National Laboratories recently completed a point design based on the 34-m Vertical Axis Wind Turbine (VAWT) Test Bed. The 34-m Test Bed research machine incorporates several innovations that improve Darrieus technology, including increased energy production, over previous machines. The point design differs minimally from the Test Bed; but by removing research-related items, its estimated cost is substantially reduced. The point design is a first step towards a Test-Bed-based commercial machine that would be competitive with conventional sources of power in the mid-1990s.

  6. The collapsed cone algorithm for (192)Ir dosimetry using phantom-size adaptive multiple-scatter point kernels.

    Science.gov (United States)

    Tedgren, Åsa Carlsson; Plamondon, Mathieu; Beaulieu, Luc

    2015-07-07

    The aim of this work was to investigate how dose distributions calculated with the collapsed cone (CC) algorithm depend on the size of the water phantom used in deriving the point kernel for multiple scatter. A research version of the CC algorithm equipped with a set of selectable point kernels for multiple-scatter dose that had initially been derived in water phantoms of various dimensions was used. The new point kernels were generated using EGSnrc in spherical water phantoms of radii 5 cm, 7.5 cm, 10 cm, 15 cm, 20 cm, 30 cm and 50 cm. Dose distributions derived with CC in water phantoms of different dimensions and in a CT-based clinical breast geometry were compared to Monte Carlo (MC) simulations using the Geant4-based brachytherapy specific MC code Algebra. Agreement with MC within 1% was obtained when the dimensions of the phantom used to derive the multiple-scatter kernel were similar to those of the calculation phantom. Doses are overestimated at phantom edges when kernels are derived in larger phantoms and underestimated when derived in smaller phantoms (by around 2% to 7% depending on distance from source and phantom dimensions). CC agrees well with MC in the high dose region of a breast implant and is superior to TG43 in determining skin doses for all multiple-scatter point kernel sizes. Increased agreement between CC and MC is achieved when the point kernel is comparable to breast dimensions. The investigated approximation in multiple scatter dose depends on the choice of point kernel in relation to phantom size and yields a significant fraction of the total dose only at distances of several centimeters from a source/implant which correspond to volumes of low doses. The current implementation of the CC algorithm utilizes a point kernel derived in a comparatively large (radius 20 cm) water phantom. A fixed point kernel leads to predictable behaviour of the algorithm with the worst case being a source/implant located well within a patient

  7. Oil-points - Designers means to evaluate sustainability of concepts

    DEFF Research Database (Denmark)

    Bey, Niki; Lenau, Torben Anker

    1998-01-01

    Designers have an essential influence on product design and are therefore one target group for environmental evaluation methods. This implies, that such evaluation methods have to meet designers requirements. Evaluation of sustainability of products is often done using formal Life Cycle Assessment....... This is investigated by means of three case studies where environmental impact is estimated using the EDIP method, the Eco-indicator 95 method, and the Oil Point method proposed by the authors. It is found that the results obtained using Oil Points are in acceptable conformity with the results obtained with more...

  8. Free Material Design with Multiple Load Cases

    DEFF Research Database (Denmark)

    Pedersen, Pauli; Pedersen, Niels Leergaard

    2012-01-01

    Multiple load cases and the consideration of strength is a reality that most structural designs are exposed to. Improved possibility to produce specific materials, say by fiber lay-up, put focus on research on free material optimization. A formulation for such design problems together with a prac......Multiple load cases and the consideration of strength is a reality that most structural designs are exposed to. Improved possibility to produce specific materials, say by fiber lay-up, put focus on research on free material optimization. A formulation for such design problems together...... with a practical recursive design procedure is presented and illustrated with examples. The presented finite element analysis involve many elements as well as many load cases. Separating the local amount of material from a description with unit trace for the local anisotropy, gives the free materials formulation...... a more physical interpretation of the material constraint....

  9. Improving multiple-point-based a priori models for inverse problems by combining Sequential Simulation with the Frequency Matching Method

    DEFF Research Database (Denmark)

    Cordua, Knud Skou; Hansen, Thomas Mejer; Lange, Katrine

    In order to move beyond simplified covariance based a priori models, which are typically used for inverse problems, more complex multiple-point-based a priori models have to be considered. By means of marginal probability distributions ‘learned’ from a training image, sequential simulation has...... proven to be an efficient way of obtaining multiple realizations that honor the same multiple-point statistics as the training image. The frequency matching method provides an alternative way of formulating multiple-point-based a priori models. In this strategy the pattern frequency distributions (i.......e. marginals) of the training image and a subsurface model are matched in order to obtain a solution with the same multiple-point statistics as the training image. Sequential Gibbs sampling is a simulation strategy that provides an efficient way of applying sequential simulation based algorithms as a priori...

  10. Automated platform for designing multiple robot work cells

    Science.gov (United States)

    Osman, N. S.; Rahman, M. A. A.; Rahman, A. A. Abdul; Kamsani, S. H.; Bali Mohamad, B. M.; Mohamad, E.; Zaini, Z. A.; Rahman, M. F. Ab; Mohamad Hatta, M. N. H.

    2017-06-01

    Designing the multiple robot work cells is very knowledge-intensive, intricate, and time-consuming process. This paper elaborates the development process of a computer-aided design program for generating the multiple robot work cells which offer a user-friendly interface. The primary purpose of this work is to provide a fast and easy platform for less cost and human involvement with minimum trial and errors adjustments. The automated platform is constructed based on the variant-shaped configuration concept with its mathematical model. A robot work cell layout, system components, and construction procedure of the automated platform are discussed in this paper where integration of these items will be able to automatically provide the optimum robot work cell design according to the information set by the user. This system is implemented on top of CATIA V5 software and utilises its Part Design, Assembly Design, and Macro tool. The current outcomes of this work provide a basis for future investigation in developing a flexible configuration system for the multiple robot work cells.

  11. Estimation of Multiple Point Sources for Linear Fractional Order Systems Using Modulating Functions

    KAUST Repository

    Belkhatir, Zehor; Laleg-Kirati, Taous-Meriem

    2017-01-01

    This paper proposes an estimation algorithm for the characterization of multiple point inputs for linear fractional order systems. First, using polynomial modulating functions method and a suitable change of variables the problem of estimating

  12. A Switching Anti-windup Design Using Multiple Lyapunov Functions

    NARCIS (Netherlands)

    Lu, L.; Lin, Z.; Chen, J.

    2009-01-01

    This paper proposes a switching anti-windup design, which aims to enlarge the domain of attraction of the closed-loop system. Multiple anti-windup gains along with an index function that orchestrates the switching among these anti-windup gains are designed based on the min function of multiple

  13. Development of a Whole-Body Haptic Sensor with Multiple Supporting Points and Its Application to a Manipulator

    Science.gov (United States)

    Hanyu, Ryosuke; Tsuji, Toshiaki

    This paper proposes a whole-body haptic sensing system that has multiple supporting points between the body frame and the end-effector. The system consists of an end-effector and multiple force sensors. Using this mechanism, the position of a contact force on the surface can be calculated without any sensor array. A haptic sensing system with a single supporting point structure has previously been developed by the present authors. However, the system has drawbacks such as low stiffness and low strength. Therefore, in this study, a mechanism with multiple supporting points was proposed and its performance was verified. In this paper, the basic concept of the mechanism is first introduced. Next, an evaluation of the proposed method, performed by conducting some experiments, is presented.

  14. Method of Fusion Diagnosis for Dam Service Status Based on Joint Distribution Function of Multiple Points

    Directory of Open Access Journals (Sweden)

    Zhenxiang Jiang

    2016-01-01

    Full Text Available The traditional methods of diagnosing dam service status are always suitable for single measuring point. These methods also reflect the local status of dams without merging multisource data effectively, which is not suitable for diagnosing overall service. This study proposes a new method involving multiple points to diagnose dam service status based on joint distribution function. The function, including monitoring data of multiple points, can be established with t-copula function. Therefore, the possibility, which is an important fusing value in different measuring combinations, can be calculated, and the corresponding diagnosing criterion is established with typical small probability theory. Engineering case study indicates that the fusion diagnosis method can be conducted in real time and the abnormal point can be detected, thereby providing a new early warning method for engineering safety.

  15. Point-to-point radio link variation at E-band and its effect on antenna design

    NARCIS (Netherlands)

    Al-Rawi, A.; Dubok, A.; Herben, M.H.A.J.; Smolders, A.B.

    2015-01-01

    Radio propagation will strongly influence the design of the antenna and front-end components of E-band point-to-point communication systems. Based on the ITU rain model, the rain attenuation is estimated in a statistical sense and it is concluded that for backhaul links of 1–10 km, antennas with a

  16. Generating and executing programs for a floating point single instruction multiple data instruction set architecture

    Science.gov (United States)

    Gschwind, Michael K

    2013-04-16

    Mechanisms for generating and executing programs for a floating point (FP) only single instruction multiple data (SIMD) instruction set architecture (ISA) are provided. A computer program product comprising a computer recordable medium having a computer readable program recorded thereon is provided. The computer readable program, when executed on a computing device, causes the computing device to receive one or more instructions and execute the one or more instructions using logic in an execution unit of the computing device. The logic implements a floating point (FP) only single instruction multiple data (SIMD) instruction set architecture (ISA), based on data stored in a vector register file of the computing device. The vector register file is configured to store both scalar and floating point values as vectors having a plurality of vector elements.

  17. A Point Kinetics Model for Estimating Neutron Multiplication of Bare Uranium Metal in Tagged Neutron Measurements

    Science.gov (United States)

    Tweardy, Matthew C.; McConchie, Seth; Hayward, Jason P.

    2017-07-01

    An extension of the point kinetics model is developed to describe the neutron multiplicity response of a bare uranium object under interrogation by an associated particle imaging deuterium-tritium (D-T) measurement system. This extended model is used to estimate the total neutron multiplication of the uranium. Both MCNPX-PoliMi simulations and data from active interrogation measurements of highly enriched and depleted uranium geometries are used to evaluate the potential of this method and to identify the sources of systematic error. The detection efficiency correction for measured coincidence response is identified as a large source of systematic error. If the detection process is not considered, results suggest that the method can estimate total multiplication to within 13% of the simulated value. Values for multiplicity constants in the point kinetics equations are sensitive to enrichment due to (n, xn) interactions by D-T neutrons and can introduce another significant source of systematic bias. This can theoretically be corrected if isotopic composition is known a priori. The spatial dependence of multiplication is also suspected of introducing further systematic bias for high multiplication uranium objects.

  18. Downscaling remotely sensed imagery using area-to-point cokriging and multiple-point geostatistical simulation

    Science.gov (United States)

    Tang, Yunwei; Atkinson, Peter M.; Zhang, Jingxiong

    2015-03-01

    A cross-scale data integration method was developed and tested based on the theory of geostatistics and multiple-point geostatistics (MPG). The goal was to downscale remotely sensed images while retaining spatial structure by integrating images at different spatial resolutions. During the process of downscaling, a rich spatial correlation model in the form of a training image was incorporated to facilitate reproduction of similar local patterns in the simulated images. Area-to-point cokriging (ATPCK) was used as locally varying mean (LVM) (i.e., soft data) to deal with the change of support problem (COSP) for cross-scale integration, which MPG cannot achieve alone. Several pairs of spectral bands of remotely sensed images were tested for integration within different cross-scale case studies. The experiment shows that MPG can restore the spatial structure of the image at a fine spatial resolution given the training image and conditioning data. The super-resolution image can be predicted using the proposed method, which cannot be realised using most data integration methods. The results show that ATPCK-MPG approach can achieve greater accuracy than methods which do not account for the change of support issue.

  19. The shooting method and multiple solutions of two/multi-point BVPs of second-order ODE

    Directory of Open Access Journals (Sweden)

    Man Kam Kwong

    2006-06-01

    Full Text Available Within the last decade, there has been growing interest in the study of multiple solutions of two- and multi-point boundary value problems of nonlinear ordinary differential equations as fixed points of a cone mapping. Undeniably many good results have emerged. The purpose of this paper is to point out that, in the special case of second-order equations, the shooting method can be an effective tool, sometimes yielding better results than those obtainable via fixed point techniques.

  20. Multiple point statistical simulation using uncertain (soft) conditional data

    Science.gov (United States)

    Hansen, Thomas Mejer; Vu, Le Thanh; Mosegaard, Klaus; Cordua, Knud Skou

    2018-05-01

    Geostatistical simulation methods have been used to quantify spatial variability of reservoir models since the 80s. In the last two decades, state of the art simulation methods have changed from being based on covariance-based 2-point statistics to multiple-point statistics (MPS), that allow simulation of more realistic Earth-structures. In addition, increasing amounts of geo-information (geophysical, geological, etc.) from multiple sources are being collected. This pose the problem of integration of these different sources of information, such that decisions related to reservoir models can be taken on an as informed base as possible. In principle, though difficult in practice, this can be achieved using computationally expensive Monte Carlo methods. Here we investigate the use of sequential simulation based MPS simulation methods conditional to uncertain (soft) data, as a computational efficient alternative. First, it is demonstrated that current implementations of sequential simulation based on MPS (e.g. SNESIM, ENESIM and Direct Sampling) do not account properly for uncertain conditional information, due to a combination of using only co-located information, and a random simulation path. Then, we suggest two approaches that better account for the available uncertain information. The first make use of a preferential simulation path, where more informed model parameters are visited preferentially to less informed ones. The second approach involves using non co-located uncertain information. For different types of available data, these approaches are demonstrated to produce simulation results similar to those obtained by the general Monte Carlo based approach. These methods allow MPS simulation to condition properly to uncertain (soft) data, and hence provides a computationally attractive approach for integration of information about a reservoir model.

  1. Multiplicative point process as a model of trading activity

    Science.gov (United States)

    Gontis, V.; Kaulakys, B.

    2004-11-01

    Signals consisting of a sequence of pulses show that inherent origin of the 1/ f noise is a Brownian fluctuation of the average interevent time between subsequent pulses of the pulse sequence. In this paper, we generalize the model of interevent time to reproduce a variety of self-affine time series exhibiting power spectral density S( f) scaling as a power of the frequency f. Furthermore, we analyze the relation between the power-law correlations and the origin of the power-law probability distribution of the signal intensity. We introduce a stochastic multiplicative model for the time intervals between point events and analyze the statistical properties of the signal analytically and numerically. Such model system exhibits power-law spectral density S( f)∼1/ fβ for various values of β, including β= {1}/{2}, 1 and {3}/{2}. Explicit expressions for the power spectra in the low-frequency limit and for the distribution density of the interevent time are obtained. The counting statistics of the events is analyzed analytically and numerically, as well. The specific interest of our analysis is related with the financial markets, where long-range correlations of price fluctuations largely depend on the number of transactions. We analyze the spectral density and counting statistics of the number of transactions. The model reproduces spectral properties of the real markets and explains the mechanism of power-law distribution of trading activity. The study provides evidence that the statistical properties of the financial markets are enclosed in the statistics of the time interval between trades. A multiplicative point process serves as a consistent model generating this statistics.

  2. Multiple contacts with diversion at the point of arrest.

    Science.gov (United States)

    Riordan, Sharon; Wix, Stuart; Haque, M Sayeed; Humphreys, Martin

    2003-04-01

    A diversion at the point of arrest (DAPA) scheme was set up in five police stations in South Birmingham in 1992. In a study of all referrals made over a four-year period a sub group of multiple contact individuals was identified. During that time four hundred and ninety-two contacts were recorded in total, of which 130 were made by 58 individuals. The latter group was generally no different from the single contact group but did have a tendency to be younger. This research highlights the need for a re-evaluation of service provision and associated education of police officers and relevant mental health care professionals.

  3. The FEROL40, a microTCA card interfacing custom point-to-point links and standard TCP/IP

    CERN Document Server

    Gigi, Dominique; Behrens, Ulf; Branson, James; Chaze, Olivier; Cittolin, Sergio; Contescu, Cristian; da Silva Gomes, Diego; Darlea, Georgiana-Lavinia; Deldicque, Christian; Demiragli, Zeynep; Dobson, Marc; Doualot, Nicolas; Erhan, Samim; Fulcher, Jonathan Richard; Gladki, Maciej; Glege, Frank; Gomez-Ceballos, Guillelmo; Hegeman, Jeroen; Holzner, Andre; Janulis, Mindaugas; Lettrich, Michael; Meijers, Frans; Meschi, Emilio; Mommsen, Remigius K; Morovic, Srecko; O'Dell, Vivian; Orn, Samuel Johan; Orsini, Luciano; Papakrivopoulos, Ioannis; Paus, Christoph; Petrova, Petia; Petrucci, Andrea; Pieri, Marco; Rabady, Dinyar; Racz, Attila; Reis, Thomas; Sakulin, Hannes; Schwick, Christoph; Simelevicius, Dainius; Vazquez Velez, Cristina; Vougioukas, Michail; Zejdl, Petr

    2017-01-01

    In order to accommodate new back-end electronics of upgraded CMS sub-detectors, a new FEROL40 card in the microTCA standard has been developed. The main function of the FEROL40 is to acquire event data over multiple point-to-point serial optical links, provide buffering, perform protocol conversion, and transmit multiple TCP/IP streams (4x10Gbps) to the Ethernet network of the aggregation layer of the CMS DAQ (data acquisition) event builder. This contribution discusses the design of the FEROL40 and experience from operation.

  4. NEWTONIAN IMPERIALIST COMPETITVE APPROACH TO OPTIMIZING OBSERVATION OF MULTIPLE TARGET POINTS IN MULTISENSOR SURVEILLANCE SYSTEMS

    Directory of Open Access Journals (Sweden)

    A. Afghan-Toloee

    2013-09-01

    Full Text Available The problem of specifying the minimum number of sensors to deploy in a certain area to face multiple targets has been generally studied in the literatures. In this paper, we are arguing the multi-sensors deployment problem (MDP. The Multi-sensor placement problem can be clarified as minimizing the cost required to cover the multi target points in the area. We propose a more feasible method for the multi-sensor placement problem. Our method makes provision the high coverage of grid based placements while minimizing the cost as discovered in perimeter placement techniques. The NICA algorithm as improved ICA (Imperialist Competitive Algorithm is used to decrease the performance time to explore an enough solution compared to other meta-heuristic schemes such as GA, PSO and ICA. A three dimensional area is used for clarify the multiple target and placement points, making provision x, y, and z computations in the observation algorithm. A structure of model for the multi-sensor placement problem is proposed: The problem is constructed as an optimization problem with the objective to minimize the cost while covering all multiple target points upon a given probability of observation tolerance.

  5. Dynamics and mission design near libration points

    CERN Document Server

    Gómez, G; Simo, C; Masdemont, J

    2001-01-01

    This book studies several problems related to the analysis of planned or possible spacecraft missions. It is divided into four chapters. The first chapter is devoted to the computation of quasiperiodic solutions for the motion of a spacecraft near the equilateral points of the Earth-Moon system. The second chapter gives a complete description of the orbits near the collinear point, L 1 , between the Earth and the Sun in the restricted three-body problem (RTBP) model. In the third chapter, methods are developed to compute the nominal orbit and to design and test the control strategy for the qua

  6. Approach and landing guidance design for reusable launch vehicle using multiple sliding surfaces technique

    Directory of Open Access Journals (Sweden)

    Xiangdong LIU

    2017-08-01

    Full Text Available An autonomous approach and landing (A&L guidance law is presented in this paper for landing an unpowered reusable launch vehicle (RLV at the designated runway touchdown. Considering the full nonlinear point-mass dynamics, a guidance scheme is developed in three-dimensional space. In order to guarantee a successful A&L movement, the multiple sliding surfaces guidance (MSSG technique is applied to derive the closed-loop guidance law, which stems from higher order sliding mode control theory and has advantage in the finite time reaching property. The global stability of the proposed guidance approach is proved by the Lyapunov-based method. The designed guidance law can generate new trajectories on-line without any specific requirement on off-line analysis except for the information on the boundary conditions of the A&L phase and instantaneous states of the RLV. Therefore, the designed guidance law is flexible enough to target different touchdown points on the runway and is capable of dealing with large initial condition errors resulted from the previous flight phase. Finally, simulation results show the effectiveness of the proposed guidance law in different scenarios.

  7. A Point Kinetics Model for Estimating Neutron Multiplication of Bare Uranium Metal in Tagged Neutron Measurements

    International Nuclear Information System (INIS)

    Tweardy, Matthew C.; McConchie, Seth; Hayward, Jason P.

    2017-01-01

    An extension of the point kinetics model is developed in this paper to describe the neutron multiplicity response of a bare uranium object under interrogation by an associated particle imaging deuterium-tritium (D-T) measurement system. This extended model is used to estimate the total neutron multiplication of the uranium. Both MCNPX-PoliMi simulations and data from active interrogation measurements of highly enriched and depleted uranium geometries are used to evaluate the potential of this method and to identify the sources of systematic error. The detection efficiency correction for measured coincidence response is identified as a large source of systematic error. If the detection process is not considered, results suggest that the method can estimate total multiplication to within 13% of the simulated value. Values for multiplicity constants in the point kinetics equations are sensitive to enrichment due to (n, xn) interactions by D-T neutrons and can introduce another significant source of systematic bias. This can theoretically be corrected if isotopic composition is known a priori. Finally, the spatial dependence of multiplication is also suspected of introducing further systematic bias for high multiplication uranium objects.

  8. Microsoft Office SharePoint Designer 2007 Step by Step

    CERN Document Server

    Coventry, Penelope

    2008-01-01

    The smart way to learn Office SharePoint Designer 2007-one step at a time! Work at your own pace through the easy numbered steps, practice files on CD, helpful hints, and troubleshooting tips to master the fundamentals of building customized SharePoint sites and applications. You'll learn how to work with Windows® SharePoint Services 3.0 and Office SharePoint Server 2007 to create Web pages complete with Cascading Style Sheets, Lists, Libraries, and customized Web parts. Then, make your site really work for you by adding data sources, including databases, XML data and Web services, and RSS fe

  9. A Survivable Wavelength Division Multiplexing Passive Optical Network with Both Point-to-Point Service and Broadcast Service Delivery

    Science.gov (United States)

    Ma, Xuejiao; Gan, Chaoqin; Deng, Shiqi; Huang, Yan

    2011-11-01

    A survivable wavelength division multiplexing passive optical network enabling both point-to-point service and broadcast service is presented and demonstrated. This architecture provides an automatic traffic recovery against feeder and distribution fiber link failure, respectively. In addition, it also simplifies the protection design for multiple services transmission in wavelength division multiplexing passive optical networks.

  10. An Asynchronous IEEE Floating-Point Arithmetic Unit

    Directory of Open Access Journals (Sweden)

    Joel R. Noche

    2007-12-01

    Full Text Available An asynchronous floating-point arithmetic unit is designed and tested at the transistor level usingCadence software. It uses CMOS (complementary metal oxide semiconductor and DCVS (differentialcascode voltage switch logic in a 0.35 µm process using a 3.3 V supply voltage, with dual-rail data andsingle-rail control signals using four-phase handshaking.Using 17,085 transistors, the unit handles single-precision (32-bit addition/subtraction, multiplication,division, and remainder using the IEEE 754-1985 Standard for Binary Floating-Point Arithmetic, withrounding and other operations to be handled by separate hardware or software. Division and remainderare done using a restoring subtractive algorithm; multiplication uses an additive algorithm. Exceptionsare noted by flags (and not trap handlers and the output is in single-precision.Previous work on asynchronous floating-point arithmetic units have mostly focused on single operationssuch as division. This is the first work to the authors' knowledge that can perform floating-point addition,multiplication, division, and remainder using a common datapath.

  11. Modeling spatial variability of sand-lenses in clay till settings using transition probability and multiple-point geostatistics

    DEFF Research Database (Denmark)

    Kessler, Timo Christian; Nilsson, Bertel; Klint, Knud Erik

    2010-01-01

    (TPROGS) of alternating geological facies. The second method, multiple-point statistics, uses training images to estimate the conditional probability of sand-lenses at a certain location. Both methods respect field observations such as local stratigraphy, however, only the multiple-point statistics can...... of sand-lenses in clay till. Sand-lenses mainly account for horizontal transport and are prioritised in this study. Based on field observations, the distribution has been modeled using two different geostatistical approaches. One method uses a Markov chain model calculating the transition probabilities...

  12. Methods of fast, multiple-point in vivo T1 determination

    International Nuclear Information System (INIS)

    Zhang, Y.; Spigarelli, M.; Fencil, L.E.; Yeung, H.N.

    1989-01-01

    Two methods of rapid, multiple-point determination of T1 in vivo have been evaluated with a phantom consisting of vials of gel in different Mn + + concentrations. The first method was an inversion-recovery- on-the-fly technique, and the second method used a variable- tip-angle (α) progressive saturation with two sub- sequences of different repetition times. In the first method, 1/T1 was evaluated by an exponential fit. In the second method, 1/T1 was obtained iteratively with a linear fit and then readjusted together with α to a model equation until self-consistency was reached

  13. Professional SharePoint 2010 Branding and User Interface Design

    CERN Document Server

    Drisgill, Randy; Sanford, Jacob J; Stubbs, Paul; Riemann, Larry

    2010-01-01

    A must have guide for creating engaging and usable SharePoint 2010 brandingWith SharePoint 2010, Microsoft has provided a more robust environment for creating collaboration and content management sites that rival any of the popular websites on the internet. Creating a branded SharePoint site involves understanding both traditional web design techniques as well as topics that are typically reserved for developers. This book bridges that gap by not only providing expert guidance for creating beautiful public facing and internal intranet sites but it also addresses the needs of those readers that

  14. Simultaneous reconstruction of multiple depth images without off-focus points in integral imaging using a graphics processing unit.

    Science.gov (United States)

    Yi, Faliu; Lee, Jieun; Moon, Inkyu

    2014-05-01

    The reconstruction of multiple depth images with a ray back-propagation algorithm in three-dimensional (3D) computational integral imaging is computationally burdensome. Further, a reconstructed depth image consists of a focus and an off-focus area. Focus areas are 3D points on the surface of an object that are located at the reconstructed depth, while off-focus areas include 3D points in free-space that do not belong to any object surface in 3D space. Generally, without being removed, the presence of an off-focus area would adversely affect the high-level analysis of a 3D object, including its classification, recognition, and tracking. Here, we use a graphics processing unit (GPU) that supports parallel processing with multiple processors to simultaneously reconstruct multiple depth images using a lookup table containing the shifted values along the x and y directions for each elemental image in a given depth range. Moreover, each 3D point on a depth image can be measured by analyzing its statistical variance with its corresponding samples, which are captured by the two-dimensional (2D) elemental images. These statistical variances can be used to classify depth image pixels as either focus or off-focus points. At this stage, the measurement of focus and off-focus points in multiple depth images is also implemented in parallel on a GPU. Our proposed method is conducted based on the assumption that there is no occlusion of the 3D object during the capture stage of the integral imaging process. Experimental results have demonstrated that this method is capable of removing off-focus points in the reconstructed depth image. The results also showed that using a GPU to remove the off-focus points could greatly improve the overall computational speed compared with using a CPU.

  15. Designing multiple ligands - medicinal chemistry strategies and challenges.

    Science.gov (United States)

    Morphy, Richard; Rankovic, Zoran

    2009-01-01

    It has been widely recognised over the recent years that parallel modulation of multiple biological targets can be beneficial for treatment of diseases with complex etiologies such as cancer asthma, and psychiatric disease. In this article, current strategies for the generation of ligands with a specific multi-target profile (designed multiple ligands or DMLs) are described and a number of illustrative example are given. Designing multiple ligands is frequently a challenging endeavour for medicinal chemists, with the need to appropriately balance affinity for 2 or more targets whilst obtaining physicochemical and pharmacokinetic properties that are consistent with the administration of an oral drug. Given that the properties of DMLs are influenced to a large extent by the proteomic superfamily to which the targets belong and the lead generation strategy that is pursued, an early assessment of the feasibility of any given DML project is essential.

  16. Assimilation of concentration measurements for retrieving multiple point releases in atmosphere: A least-squares approach to inverse modelling

    Science.gov (United States)

    Singh, Sarvesh Kumar; Rani, Raj

    2015-10-01

    The study addresses the identification of multiple point sources, emitting the same tracer, from their limited set of merged concentration measurements. The identification, here, refers to the estimation of locations and strengths of a known number of simultaneous point releases. The source-receptor relationship is described in the framework of adjoint modelling by using an analytical Gaussian dispersion model. A least-squares minimization framework, free from an initialization of the release parameters (locations and strengths), is presented to estimate the release parameters. This utilizes the distributed source information observable from the given monitoring design and number of measurements. The technique leads to an exact retrieval of the true release parameters when measurements are noise free and exactly described by the dispersion model. The inversion algorithm is evaluated using the real data from multiple (two, three and four) releases conducted during Fusion Field Trials in September 2007 at Dugway Proving Ground, Utah. The release locations are retrieved, on average, within 25-45 m of the true sources with the distance from retrieved to true source ranging from 0 to 130 m. The release strengths are also estimated within a factor of three to the true release rates. The average deviations in retrieval of source locations are observed relatively large in two release trials in comparison to three and four release trials.

  17. Robust set-point regulation for ecological models with multiple management goals.

    Science.gov (United States)

    Guiver, Chris; Mueller, Markus; Hodgson, Dave; Townley, Stuart

    2016-05-01

    Population managers will often have to deal with problems of meeting multiple goals, for example, keeping at specific levels both the total population and population abundances in given stage-classes of a stratified population. In control engineering, such set-point regulation problems are commonly tackled using multi-input, multi-output proportional and integral (PI) feedback controllers. Building on our recent results for population management with single goals, we develop a PI control approach in a context of multi-objective population management. We show that robust set-point regulation is achieved by using a modified PI controller with saturation and anti-windup elements, both described in the paper, and illustrate the theory with examples. Our results apply more generally to linear control systems with positive state variables, including a class of infinite-dimensional systems, and thus have broader appeal.

  18. Design of a Ku band miniature multiple beam klystron

    Energy Technology Data Exchange (ETDEWEB)

    Bandyopadhyay, Ayan Kumar, E-mail: ayan.bandyopadhyay@gmail.com; Pal, Debasish; Kant, Deepender [Microwave Tubes Division, CSIR-CEERI, Pilani, Rajasthan-333031 (India); Saini, Anil; Saha, Sukalyan; Joshi, Lalit Mohan

    2016-03-09

    The design of a miniature multiple beam klystron (MBK) working in the Ku-band frequency range is presented in this article. Starting from the main design parameters, design of the electron gun, the input and output couplers and radio frequency section (RF-section) are presented. The design methodology using state of the art commercial electromagnetic design tools, analytical formulae as well as noncommercial design tools are briefly presented in this article.

  19. Design and development of multiple sample counting setup

    International Nuclear Information System (INIS)

    Rath, D.P.; Murali, S.; Babu, D.A.R.

    2010-01-01

    Full text: The analysis of active samples on regular basis for ambient air activity and floor contamination from radio chemical lab accounts for major chunk of the operational activity in Health Physicist's responsibility. The requirement for daily air sample analysis on immediate counting and delayed counting from various labs in addition to samples of smear swipe check of lab led to the urge for development of system that could cater multiple sample analysis in a time programmed manner on a single sample loading. A multiple alpha/beta counting system for counting was designed and fabricated. It has arrangements for loading 10 samples in slots in order, get counted in a time programmed manner with results displayed and records maintained in PC. The paper describes the design and development of multiple sample counting setup presently in use at the facility has resulted in reduction of man-hour consumption in counting and recording of the results

  20. A novel design of submicron thin film point contacts

    International Nuclear Information System (INIS)

    Koch, H.

    1986-01-01

    A thin film point contact design applicable to SIS-, SNS-, and microbridge-type Josephson junctions is presented, which offers potentially advanced junction characteristics (low capacitance, low stray inductance, increased quasi-particle resistance). The design philosophy is based on the fact that a point contact results if two planes having a common symmetry axis but oriented perpendicular to each other are brought into contact with each other. For the case of thin films, instead of two-dimensional planes, the cross section of the resulting ''point''-contact is defined by the thicknesses of the two thin films. Film thicknesses can be controlled much more precisely than lateral dimensions created by lithography. Hence, submicron junction geometries can be achieved using only conventional fabrication techniques. Following this idea, Josephson weak links of the ultrashort microbridge-type have been fabricated by an all-Nb technique having a 0.3-μm X 0.2-μm cross section with a R /SUB q/ I /SUB c/ product (R /SUB q/ = quasiparticle resistance, I /SUB c/ = critical current) of more than 20 mV

  1. Performance analysis of commercial multiple-input-multiple-output access point in distributed antenna system.

    Science.gov (United States)

    Fan, Yuting; Aighobahi, Anthony E; Gomes, Nathan J; Xu, Kun; Li, Jianqiang

    2015-03-23

    In this paper, we experimentally investigate the throughput of IEEE 802.11n 2x2 multiple-input-multiple-output (MIMO) signals in a radio-over-fiber-based distributed antenna system (DAS) with different fiber lengths and power imbalance. Both a MIMO-supported access point (AP) and a spatial-diversity-supported AP were separately employed in the experiments. Throughput measurements were carried out with wireless users at different locations in a typical office environment. For the different fiber length effect, the results indicate that MIMO signals can maintain high throughput when the fiber length difference between the two remote antenna units (RAUs) is under 100 m and falls quickly when the length difference is greater. For the spatial diversity signals, high throughput can be maintained even when the difference is 150 m. On the other hand, the separation of the MIMO antennas allows additional freedom in placing the antennas in strategic locations for overall improved system performance, although it may also lead to received power imbalance problems. The results show that the throughput performance drops in specific positions when the received power imbalance is above around 13 dB. Hence, there is a trade-off between the extent of the wireless coverage for moderate bit-rates and the area over which peak bit-rates can be achieved.

  2. Fiber design and realization of point-by-point written fiber Bragg gratings in polymer optical fibers

    DEFF Research Database (Denmark)

    Stefani, Alessio; Stecher, Matthias; Town, Graham E.

    2012-01-01

    the gratings make the point-by-point grating writing technique very interesting and would appear to be able to fill this technological gap. On the other end this technique is hardly applicable for microstructured fibers because of the writing beam being scattered by the air-holes. We report on the design...... and because they allow to tune the guiding parameters by modifying the microstructure. Now a days the only technique used to write gratings in such fibers is the phase mask technique with UV light illumination. Despite the good results that have been obtained, a limited flexibility on the grating design...... and the very long times required for the writing of FBGs raise some questions about the possibility of exporting POF FBGs and the sensors based on them from the laboratory bench to the mass production market. The possibility of arbitrary design of fiber Bragg gratings and the very short time required to write...

  3. Structural Design of Systems with Safe Behavior under Single and Multiple Faults

    DEFF Research Database (Denmark)

    Blanke, Mogens; Staroswiecki, Marcel

    2006-01-01

    Handling of multiple simultaneous faults is a complex issue in fault-tolerant control. The design task is particularly made difficult by to the numerous different cases that need be analyzed. Aiming at safe fault-handling, this paper shows how structural analysis can be applied to find...... to structural analysis to disclose which faults could be isolated from a structural point of view using active fault isolation. Results from application on a marine control system illustrate the concepts....... the analytical redundancy relations for all relevant combinations of faults, and can cope with the complexity and size of a real system. Being essential for fault-tolerant control schemes that shall handle particular cases of faults/failures, fault isolation is addressed. The paper introduces an extension...

  4. Optimal Design of Fixed-Point and Floating-Point Arithmetic Units for Scientific Applications

    OpenAIRE

    Pongyupinpanich, Surapong

    2012-01-01

    The challenge in designing a floating-point arithmetic co-processor/processor for scientific and engineering applications is to improve the performance, efficiency, and computational accuracy of the arithmetic unit. The arithmetic unit should efficiently support several mathematical functions corresponding to scientific and engineering computation demands. Moreover, the computations should be performed as fast as possible with a high degree of accuracy. Thus, this thesis proposes algorithm, d...

  5. Multiple-point statistical prediction on fracture networks at Yucca Mountain

    International Nuclear Information System (INIS)

    Liu, X.Y; Zhang, C.Y.; Liu, Q.S.; Birkholzer, J.T.

    2009-01-01

    In many underground nuclear waste repository systems, such as at Yucca Mountain, water flow rate and amount of water seepage into the waste emplacement drifts are mainly determined by hydrological properties of fracture network in the surrounding rock mass. Natural fracture network system is not easy to describe, especially with respect to its connectivity which is critically important for simulating the water flow field. In this paper, we introduced a new method for fracture network description and prediction, termed multi-point-statistics (MPS). The process of the MPS method is to record multiple-point statistics concerning the connectivity patterns of a fracture network from a known fracture map, and to reproduce multiple-scale training fracture patterns in a stochastic manner, implicitly and directly. It is applied to fracture data to study flow field behavior at the Yucca Mountain waste repository system. First, the MPS method is used to create a fracture network with an original fracture training image from Yucca Mountain dataset. After we adopt a harmonic and arithmetic average method to upscale the permeability to a coarse grid, THM simulation is carried out to study near-field water flow in the surrounding waste emplacement drifts. Our study shows that connectivity or patterns of fracture networks can be grasped and reconstructed by MPS methods. In theory, it will lead to better prediction of fracture system characteristics and flow behavior. Meanwhile, we can obtain variance from flow field, which gives us a way to quantify model uncertainty even in complicated coupled THM simulations. It indicates that MPS can potentially characterize and reconstruct natural fracture networks in a fractured rock mass with advantages of quantifying connectivity of fracture system and its simulation uncertainty simultaneously.

  6. Channel capacity of TDD-OFDM-MIMO for multiple access points in a wireless single-frequency-network

    DEFF Research Database (Denmark)

    Takatori, Y.; Fitzek, Frank; Tsunekawa, K.

    2005-01-01

    MIMO data transmission scheme, which combines Single-Frequency-Network (SFN) with TDD-OFDM-MIMO applied for wireless LAN networks. In our proposal, we advocate to use SFN for multiple access points (MAP) MIMO data transmission. The goal of this approach is to achieve very high channel capacity in both......The multiple-input-multiple-output (MIMO) technique is the most attractive candidate to improve the spectrum efficiency in the next generation wireless communication systems. However, the efficiency of MIMO techniques reduces in the line of sight (LOS) environments. In this paper, we propose a new...

  7. Multivariant design and multiple criteria analysis of building refurbishments

    Energy Technology Data Exchange (ETDEWEB)

    Kaklauskas, A.; Zavadskas, E. K.; Raslanas, S. [Faculty of Civil Engineering, Vilnius Gediminas Technical University, Vilnius (Lithuania)

    2005-07-01

    In order to design and realize an efficient building refurbishment, it is necessary to carry out an exhaustive investigation of all solutions that form it. The efficiency level of the considered building's refurbishment depends on a great many of factors, including: cost of refurbishment, annual fuel economy after refurbishment, tentative pay-back time, harmfulness to health of the materials used, aesthetics, maintenance properties, functionality, comfort, sound insulation and longevity, etc. Solutions of an alternative character allow for a more rational and realistic assessment of economic, ecological, legislative, climatic, social and political conditions, traditions and for better the satisfaction of customer requirements. They also enable one to cut down on refurbishment costs. In carrying out the multivariant design and multiple criteria analysis of a building refurbishment much data was processed and evaluated. Feasible alternatives could be as many as 100,000. How to perform a multivariant design and multiple criteria analysis of alternate alternatives based on the enormous amount of information became the problem. Method of multivariant design and multiple criteria of a building refurbishment's analysis were developed by the authors to solve the above problems. In order to demonstrate the developed method, a practical example is presented in this paper. (author)

  8. Point spread function due to multiple scattering of light in the atmosphere

    International Nuclear Information System (INIS)

    Pękala, J.; Wilczyński, H.

    2013-01-01

    The atmospheric scattering of light has a significant influence on the results of optical observations of air showers. It causes attenuation of direct light from the shower, but also contributes a delayed signal to the observed light. The scattering of light therefore should be accounted for, both in simulations of air shower detection and reconstruction of observed events. In this work a Monte Carlo simulation of multiple scattering of light has been used to determine the contribution of the scattered light in observations of a point source of light. Results of the simulations and a parameterization of the angular distribution of the scattered light contribution to the observed signal (the point spread function) are presented. -- Author-Highlights: •Analysis of atmospheric scattering of light from an isotropic point source. •Different geometries and atmospheric conditions were investigated. •A parameterization of scattered light distribution has been developed. •The parameterization allows one to easily account for the light scattering in air. •The results will be useful in analyses of observations of extensive air shower

  9. design, construction and performance evaluation of multiple casting

    African Journals Online (AJOL)

    eobe

    time taken for solidification, plays an important role in the casting. There should not ... Keywords: Design, Construction, Multiple casting machine, Compo Casting operation. 1. Introduction .... metal and pathway channel pipe with heater is used.

  10. Solving the multiple-set split equality common fixed-point problem of firmly quasi-nonexpansive operators.

    Science.gov (United States)

    Zhao, Jing; Zong, Haili

    2018-01-01

    In this paper, we propose parallel and cyclic iterative algorithms for solving the multiple-set split equality common fixed-point problem of firmly quasi-nonexpansive operators. We also combine the process of cyclic and parallel iterative methods and propose two mixed iterative algorithms. Our several algorithms do not need any prior information about the operator norms. Under mild assumptions, we prove weak convergence of the proposed iterative sequences in Hilbert spaces. As applications, we obtain several iterative algorithms to solve the multiple-set split equality problem.

  11. A Comparison of Combustion Dynamics for Multiple 7-Point Lean Direct Injection Combustor Configurations

    Science.gov (United States)

    Tacina, K. M.; Hicks, Y. R.

    2017-01-01

    The combustion dynamics of multiple 7-point lean direct injection (LDI) combustor configurations are compared. LDI is a fuel-lean combustor concept for aero gas turbine engines in which multiple small fuel-air mixers replace one traditionally-sized fuel-air mixer. This 7-point LDI configuration has a circular cross section, with a center (pilot) fuel-air mixer surrounded by six outer (main) fuel-air mixers. Each fuel-air mixer consists of an axial air swirler followed by a converging-diverging venturi. A simplex fuel injector is inserted through the center of the air swirler, with the fuel injector tip located near the venturi throat. All 7 fuel-air mixers are identical except for the swirler blade angle, which varies with the configuration. Testing was done in a 5-atm flame tube with inlet air temperatures from 600 to 800 F and equivalence ratios from 0.4 to 0.7. Combustion dynamics were measured using a cooled PCB pressure transducer flush-mounted in the wall of the combustor test section.

  12. 77 FR 34211 - Modification of Multiple Compulsory Reporting Points; Continental United States, Alaska and Hawaii

    Science.gov (United States)

    2012-06-11

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2012-0130; Airspace Docket No. 12-AWA-2] RIN 2120-AA66 Modification of Multiple Compulsory Reporting Points; Continental United States, Alaska and Hawaii AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final...

  13. A superlinear interior points algorithm for engineering design optimization

    Science.gov (United States)

    Herskovits, J.; Asquier, J.

    1990-01-01

    We present a quasi-Newton interior points algorithm for nonlinear constrained optimization. It is based on a general approach consisting of the iterative solution in the primal and dual spaces of the equalities in Karush-Kuhn-Tucker optimality conditions. This is done in such a way to have primal and dual feasibility at each iteration, which ensures satisfaction of those optimality conditions at the limit points. This approach is very strong and efficient, since at each iteration it only requires the solution of two linear systems with the same matrix, instead of quadratic programming subproblems. It is also particularly appropriate for engineering design optimization inasmuch at each iteration a feasible design is obtained. The present algorithm uses a quasi-Newton approximation of the second derivative of the Lagrangian function in order to have superlinear asymptotic convergence. We discuss theoretical aspects of the algorithm and its computer implementation.

  14. The Challenges of Designing Digital Services for Multiple Mobile Platforms

    DEFF Research Database (Denmark)

    Ghazawneh, Ahmad

    2016-01-01

    on a multiple case study of three mobile application development firms from Sweden, Denmark and Norway, we synthesize the digital service design taxonomy to understand the challenges faced by third-party developers. Our study identifies a set of challenges in four different levels: user level, platform level...... to tap into and join the digital ecosystem. However, while there is an emerging literature on designing digital services, little empirical evidence exists about challenges faced by third-party developers while designing digital services, and in particular for multiple mobile platforms. Drawing......The value of digital services is increasingly recognized by owners of digital platforms. These services have central role in building and sustaining the business of the digital platform. In order to sustain the design of digital services, owners of digital platforms encourage third-party developers...

  15. Reliability of impingement sampling designs: An example from the Indian Point station

    International Nuclear Information System (INIS)

    Mattson, M.T.; Waxman, J.B.; Watson, D.A.

    1988-01-01

    A 4-year data base (1976-1979) of daily fish impingement counts at the Indian Point electric power station on the Hudson River was used to compare the precision and reliability of three random-sampling designs: (1) simple random, (2) seasonally stratified, and (3) empirically stratified. The precision of daily impingement estimates improved logarithmically for each design as more days in the year were sampled. Simple random sampling was the least, and empirically stratified sampling was the most precise design, and the difference in precision between the two stratified designs was small. Computer-simulated sampling was used to estimate the reliability of the two stratified-random-sampling designs. A seasonally stratified sampling design was selected as the most appropriate reduced-sampling program for Indian Point station because: (1) reasonably precise and reliable impingement estimates were obtained using this design for all species combined and for eight common Hudson River fish by sampling only 30% of the days in a year (110 d); and (2) seasonal strata may be more precise and reliable than empirical strata if future changes in annual impingement patterns occur. The seasonally stratified design applied to the 1976-1983 Indian Point impingement data showed that selection of sampling dates based on daily species-specific impingement variability gave results that were more precise, but not more consistently reliable, than sampling allocations based on the variability of all fish species combined. 14 refs., 1 fig., 6 tabs

  16. Design of Endoscopic Capsule With Multiple Cameras.

    Science.gov (United States)

    Gu, Yingke; Xie, Xiang; Li, Guolin; Sun, Tianjia; Wang, Dan; Yin, Zheng; Zhang, Pengfei; Wang, Zhihua

    2015-08-01

    In order to reduce the miss rate of the wireless capsule endoscopy, in this paper, we propose a new system of the endoscopic capsule with multiple cameras. A master-slave architecture, including an efficient bus architecture and a four level clock management architecture, is applied for the Multiple Cameras Endoscopic Capsule (MCEC). For covering more area of the gastrointestinal tract wall with low power, multiple cameras with a smart image capture strategy, including movement sensitive control and camera selection, are used in the MCEC. To reduce the data transfer bandwidth and power consumption to prolong the MCEC's working life, a low complexity image compressor with PSNR 40.7 dB and compression rate 86% is implemented. A chipset is designed and implemented for the MCEC and a six cameras endoscopic capsule prototype is implemented by using the chipset. With the smart image capture strategy, the coverage rate of the MCEC prototype can achieve 98% and its power consumption is only about 7.1 mW.

  17. Design of Multiple Bolted Connections for Laminated Veneer Lumber

    Science.gov (United States)

    Borjen Yeh; Douglas Rammer; Jeff Linville

    2014-01-01

    The design of multiple bolted connections in accordance with Appendix E of the National Design Specification for Wood Construction (NDS) has incorporated provisions for evaluating localized member failure modes of row and group tear-out when the connections are closely spaced. Originally based on structural glued laminated timber (glulam) members made with all L1...

  18. Adaptive Waveform Design for Cognitive Radar in Multiple Targets Situations

    Directory of Open Access Journals (Sweden)

    Xiaowen Zhang

    2018-02-01

    Full Text Available In this paper, the problem of cognitive radar (CR waveform optimization design for target detection and estimation in multiple extended targets situations is investigated. This problem is analyzed in signal-dependent interference, as well as additive channel noise for extended targets with unknown target impulse response (TIR. To address this problem, an improved algorithm is employed for target detection by maximizing the detection probability of the received echo on the promise of ensuring the TIR estimation precision. In this algorithm, an additional weight vector is introduced to achieve a trade-off among different targets. Both the estimate of TIR and transmit waveform can be updated at each step based on the previous step. Under the same constraint on waveform energy and bandwidth, the information theoretical approach is also considered. In addition, the relationship between the waveforms that are designed based on the two criteria is discussed. Unlike most existing works that only consider single target with temporally correlated characteristics, waveform design for multiple extended targets is considered in this method. Simulation results demonstrate that compared with linear frequency modulated (LFM signal, waveforms designed based on maximum detection probability and maximum mutual information (MI criteria can make radar echoes contain more multiple-target information and improve radar performance as a result.

  19. A Design Study to Develop Young Children's Understanding of Multiplication and Division

    Science.gov (United States)

    Bicknell, Brenda; Young-Loveridge, Jenny; Nguyen, Nhung

    2016-01-01

    This design study investigated the use of multiplication and division problems to help 5-year-old children develop an early understanding of multiplication and division. One teacher and her class of 15 5-year-old children were involved in a collaborative partnership with the researchers. The design study was conducted over two 4-week periods in…

  20. Optimal design of compact and connected nature reserves for multiple species.

    Science.gov (United States)

    Wang, Yicheng; Önal, Hayri

    2016-04-01

    When designing a conservation reserve system for multiple species, spatial attributes of the reserves must be taken into account at species level. The existing optimal reserve design literature considers either one spatial attribute or when multiple attributes are considered the analysis is restricted only to one species. We built a linear integer programing model that incorporates compactness and connectivity of the landscape reserved for multiple species. The model identifies multiple reserves that each serve a subset of target species with a specified coverage probability threshold to ensure the species' long-term survival in the reserve, and each target species is covered (protected) with another probability threshold at the reserve system level. We modeled compactness by minimizing the total distance between selected sites and central sites, and we modeled connectivity of a selected site to its designated central site by selecting at least one of its adjacent sites that has a nearer distance to the central site. We considered structural distance and functional distances that incorporated site quality between sites. We tested the model using randomly generated data on 2 species, one ground species that required structural connectivity and the other an avian species that required functional connectivity. We applied the model to 10 bird species listed as endangered by the state of Illinois (U.S.A.). Spatial coherence and selection cost of the reserves differed substantially depending on the weights assigned to these 2 criteria. The model can be used to design a reserve system for multiple species, especially species whose habitats are far apart in which case multiple disjunct but compact and connected reserves are advantageous. The model can be modified to increase or decrease the distance between reserves to reduce or promote population connectivity. © 2015 Society for Conservation Biology.

  1. On strength design using free material subjected to multiple load cases

    DEFF Research Database (Denmark)

    Pedersen, Pauli; Pedersen, Niels Leergaard

    2013-01-01

    Multiple load cases and the consideration of strength is a reality that most structural designs are exposed to. Improved possibility to produce specific materials, say by fiber lay-up, put focus on research on free material optimization. A formulation for such design problems together with a prac......Multiple load cases and the consideration of strength is a reality that most structural designs are exposed to. Improved possibility to produce specific materials, say by fiber lay-up, put focus on research on free material optimization. A formulation for such design problems together...... with a practical recursive design procedure is presented and illustrated with examples. The presented finite element analysis involve many elements as well as many load cases. Separating the local amount of material from a description with unit trace for the local anisotropy, gives the free materials formulation...

  2. Turning challenges into design principles: Telemonitoring systems for patients with multiple chronic conditions.

    Science.gov (United States)

    Sultan, Mehwish; Kuluski, Kerry; McIsaac, Warren J; Cafazzo, Joseph A; Seto, Emily

    2018-01-01

    People with multiple chronic conditions often struggle with managing their health. The purpose of this research was to identify specific challenges of patients with multiple chronic conditions and to use the findings to form design principles for a telemonitoring system tailored for these patients. Semi-structured interviews with 15 patients with multiple chronic conditions and 10 clinicians were conducted to gain an understanding of their needs and preferences for a smartphone-based telemonitoring system. The interviews were analyzed using a conventional content analysis technique, resulting in six themes. Design principles developed from the themes included that the system must be modular to accommodate various combinations of conditions, reinforce a routine, consolidate record keeping, as well as provide actionable feedback to the patients. Designing an application for multiple chronic conditions is complex due to variability in patient conditions, and therefore, design principles developed in this study can help with future innovations aimed to help manage this population.

  3. Compact reversed-field pinch reactors (CRFPR): sensitivity study and design-point determination

    International Nuclear Information System (INIS)

    Hagenson, R.L.; Krakowski, R.A.

    1982-07-01

    If the costing assumptions upon which the positive assessment of conventional large superconducting fusion reactors are based proves overly optimistic, approaches that promise considerably increased system power density and reduced mass utilization will be required. These more compact reactor embodiments generally must operate with reduced shield thickness and resistive magnets. Because of the unique, magnetic topology associated with the Reversed-Field Pinch (RFP), the compact reactor embodiment for this approach is particularly attractive from the viewpoint of low-field resistive coils operating with Ohmic losses that can be made small relative to the fusion power. A comprehensive system model is developed and described for a steady-state, compact RFP reactor (CRFPR). This model is used to select a unique cost-optimized design point that will be used for a conceptual engineering design. The cost-optimized CRFPR design presented herein would operate with system power densities and mass utilizations that are comparable to fission power plants and are an order of magnitude more favorable than the conventional approaches to magnetic fusion power. The sensitivity of the base-case design point to changes in plasma transport, profiles, beta, blanket thickness, normal vs superconducting coils, and fuel cycle (DT vs DD) is examined. The RFP approach is found to yield a point design for a high-power-density reactor that is surprisingly resilient to changes in key, but relatively unknown, physics and systems parameters

  4. An efficient method for the prediction of deleterious multiple-point mutations in the secondary structure of RNAs using suboptimal folding solutions

    Directory of Open Access Journals (Sweden)

    Barash Danny

    2008-04-01

    Full Text Available Abstract Background RNAmute is an interactive Java application which, given an RNA sequence, calculates the secondary structure of all single point mutations and organizes them into categories according to their similarity to the predicted structure of the wild type. The secondary structure predictions are performed using the Vienna RNA package. A more efficient implementation of RNAmute is needed, however, to extend from the case of single point mutations to the general case of multiple point mutations, which may often be desired for computational predictions alongside mutagenesis experiments. But analyzing multiple point mutations, a process that requires traversing all possible mutations, becomes highly expensive since the running time is O(nm for a sequence of length n with m-point mutations. Using Vienna's RNAsubopt, we present a method that selects only those mutations, based on stability considerations, which are likely to be conformational rearranging. The approach is best examined using the dot plot representation for RNA secondary structure. Results Using RNAsubopt, the suboptimal solutions for a given wild-type sequence are calculated once. Then, specific mutations are selected that are most likely to cause a conformational rearrangement. For an RNA sequence of about 100 nts and 3-point mutations (n = 100, m = 3, for example, the proposed method reduces the running time from several hours or even days to several minutes, thus enabling the practical application of RNAmute to the analysis of multiple-point mutations. Conclusion A highly efficient addition to RNAmute that is as user friendly as the original application but that facilitates the practical analysis of multiple-point mutations is presented. Such an extension can now be exploited prior to site-directed mutagenesis experiments by virologists, for example, who investigate the change of function in an RNA virus via mutations that disrupt important motifs in its secondary

  5. Design and Implementation of an IoT Access Point for Smart Home

    Directory of Open Access Journals (Sweden)

    Chih-Yung Chang

    2015-12-01

    Full Text Available Network communication and micro-electro-mechanical embedded technologies have attracted much attention in recent years. Through these technologies, the capabilities of sensing, identification, and communication can be embedded in various smart devices. These smart devices can automatically connect to the Internet and form an intelligent network called Internet of Things (IoT. However, these devices are embedded with different wireless communication interfaces such as Wi-Fi and ZigBee. This paper presents the design and implementation of an IoT access point that supports functionalities of coordination of various wireless transmission protocols. Based on the existing Wi-Fi access point, we have embedded a ZigBee module and implemented ZigBee and UPnP protocols into the designed IoT access point, which supports ZigBee communication capabilities over the Internet.

  6. Hinkley Point 'C' power station public inquiry: proof of evidence on design and safety

    International Nuclear Information System (INIS)

    George, B.V.

    1988-09-01

    A public inquiry has been set up to examine the planning application made by the Central Electricity Generating Board (CEGB) for the construction of a 1200 MW Pressurized Water Reactor power station at Hinkley Point (Hinkley Point ''C'') in the United Kingdom. The policy is to replicate the Sizewell ''B'' PWR design. The Hinkley Point ''C'' design is described indicating where changes in the Sizewell ''B'' design have been made to accommodate site differences. These are associated with the civil engineering construction and some of the electrical systems and do not affect the safety case. External hazards differ from site to site and the effect on the safety case of those specific to Hinkley Point are examined. The Chernobyl accident and the assessment of the United Kingdom PWR which was carried out subsequently are reviewed. The assessment indicated that no changes in the Sizewell ''B'' design and safety case were called for as a result of this accident; accident management developments are also reviewed, however. The CEGB's approach to minimizing occupational radiation doses is described. (UK)

  7. Multiple-Panel Cylindrical Solar Concentrator

    Science.gov (United States)

    Brown, E. M.

    1983-01-01

    Trough composed of many panels concentrates Sun's energy on solar cells, even when trough is not pointed directly at Sun. Tolerates deviation as great as 5 degrees from direction of sun. For terrestrial applications, multiple-flat-plate design offers potential cost reduction and ease of fabrication.

  8. Dynamic analysis of multiple nuclear-coupled boiling channels based on a multi-point reactor model

    International Nuclear Information System (INIS)

    Lee, J.D.; Pan Chin

    2005-01-01

    This work investigates the non-linear dynamics and stabilities of a multiple nuclear-coupled boiling channel system based on a multi-point reactor model using the Galerkin nodal approximation method. The nodal approximation method for the multiple boiling channels developed by Lee and Pan [Lee, J.D., Pan, C., 1999. Dynamics of multiple parallel boiling channel systems with forced flows. Nucl. Eng. Des. 192, 31-44] is extended to address the two-phase flow dynamics in the present study. The multi-point reactor model, modified from Uehiro et al. [Uehiro, M., Rao, Y.F., Fukuda, K., 1996. Linear stability analysis on instabilities of in-phase and out-of-phase modes in boiling water reactors. J. Nucl. Sci. Technol. 33, 628-635], is employed to study a multiple-channel system with unequal steady-state neutron density distribution. Stability maps, non-linear dynamics and effects of major parameters on the multiple nuclear-coupled boiling channel system subject to a constant total flow rate are examined. This study finds that the void-reactivity feedback and neutron interactions among subcores are coupled and their competing effects may influence the system stability under different operating conditions. For those cases with strong neutron interaction conditions, by strengthening the void-reactivity feedback, the nuclear-coupled effect on the non-linear dynamics may induce two unstable oscillation modes, the supercritical Hopf bifurcation and the subcritical Hopf bifurcation. Moreover, for those cases with weak neutron interactions, by quadrupling the void-reactivity feedback coefficient, period-doubling and complex chaotic oscillations may appear in a three-channel system under some specific operating conditions. A unique type of complex chaotic attractor may evolve from the Rossler attractor because of the coupled channel-to-channel thermal-hydraulic and subcore-to-subcore neutron interactions. Such a complex chaotic attractor has the imbedding dimension of 5 and the

  9. Estimation of Multiple Point Sources for Linear Fractional Order Systems Using Modulating Functions

    KAUST Repository

    Belkhatir, Zehor

    2017-06-28

    This paper proposes an estimation algorithm for the characterization of multiple point inputs for linear fractional order systems. First, using polynomial modulating functions method and a suitable change of variables the problem of estimating the locations and the amplitudes of a multi-pointwise input is decoupled into two algebraic systems of equations. The first system is nonlinear and solves for the time locations iteratively, whereas the second system is linear and solves for the input’s amplitudes. Second, closed form formulas for both the time location and the amplitude are provided in the particular case of single point input. Finally, numerical examples are given to illustrate the performance of the proposed technique in both noise-free and noisy cases. The joint estimation of pointwise input and fractional differentiation orders is also presented. Furthermore, a discussion on the performance of the proposed algorithm is provided.

  10. Dual keel Space Station payload pointing system design and analysis feasibility study

    Science.gov (United States)

    Smagala, Tom; Class, Brian F.; Bauer, Frank H.; Lebair, Deborah A.

    1988-01-01

    A Space Station attached Payload Pointing System (PPS) has been designed and analyzed. The PPS is responsible for maintaining fixed payload pointing in the presence of disturbance applied to the Space Station. The payload considered in this analysis is the Solar Optical Telescope. System performance is evaluated via digital time simulations by applying various disturbance forces to the Space Station. The PPS meets the Space Station articulated pointing requirement for all disturbances except Shuttle docking and some centrifuge cases.

  11. Design of ultrasonically-activatable nanoparticles using low boiling point perfluorocarbons.

    Science.gov (United States)

    Sheeran, Paul S; Luois, Samantha H; Mullin, Lee B; Matsunaga, Terry O; Dayton, Paul A

    2012-04-01

    Recently, an interest has developed in designing biomaterials for medical ultrasonics that can provide the acoustic activity of microbubbles, but with improved stability in vivo and a smaller size distribution for extravascular interrogation. One proposed alternative is the phase-change contrast agent. Phase-change contrast agents (PCCAs) consist of perfluorocarbons (PFCs) that are initially in liquid form, but can then be vaporized with acoustic energy. Crucial parameters for PCCAs include their sensitivity to acoustic energy, their size distribution, and their stability, and this manuscript provides insight into the custom design of PCCAs for balancing these parameters. Specifically, the relationship between size, thermal stability and sensitivity to ultrasound as a function of PFC boiling point and ambient temperature is illustrated. Emulsion stability and sensitivity can be 'tuned' by mixing PFCs in the gaseous state prior to condensation. Novel observations illustrate that stable droplets can be generated from PFCs with extremely low boiling points, such as octafluoropropane (b.p. -36.7 °C), which can be vaporized with acoustic parameters lower than previously observed. Results demonstrate the potential for low boiling point PFCs as a useful new class of compounds for activatable agents, which can be tailored to the desired application. Copyright © 2012 Elsevier Ltd. All rights reserved.

  12. Fuzzy Controller Design Using FPGA for Photovoltaic Maximum Power Point Tracking

    OpenAIRE

    Basil M Hamed; Mohammed S. El-Moghany

    2012-01-01

    The cell has optimum operating point to be able to get maximum power. To obtain Maximum Power from photovoltaic array, photovoltaic power system usually requires Maximum Power Point Tracking (MPPT) controller. This paper provides a small power photovoltaic control system based on fuzzy control with FPGA technology design and implementation for MPPT. The system composed of photovoltaic module, buck converter and the fuzzy logic controller implemented on FPGA for controlling on/off time of MOSF...

  13. Design of Automatic Extraction Algorithm of Knowledge Points for MOOCs

    Directory of Open Access Journals (Sweden)

    Haijian Chen

    2015-01-01

    Full Text Available In recent years, Massive Open Online Courses (MOOCs are very popular among college students and have a powerful impact on academic institutions. In the MOOCs environment, knowledge discovery and knowledge sharing are very important, which currently are often achieved by ontology techniques. In building ontology, automatic extraction technology is crucial. Because the general methods of text mining algorithm do not have obvious effect on online course, we designed automatic extracting course knowledge points (AECKP algorithm for online course. It includes document classification, Chinese word segmentation, and POS tagging for each document. Vector Space Model (VSM is used to calculate similarity and design the weight to optimize the TF-IDF algorithm output values, and the higher scores will be selected as knowledge points. Course documents of “C programming language” are selected for the experiment in this study. The results show that the proposed approach can achieve satisfactory accuracy rate and recall rate.

  14. Multiple Positive Solutions of a Nonlinear Four-Point Singular Boundary Value Problem with a p-Laplacian Operator on Time Scales

    Directory of Open Access Journals (Sweden)

    Shihuang Hong

    2009-01-01

    Full Text Available We present sufficient conditions for the existence of at least twin or triple positive solutions of a nonlinear four-point singular boundary value problem with a p-Laplacian dynamic equation on a time scale. Our results are obtained via some new multiple fixed point theorems.

  15. Characterization and Design of Digital Pointing Subsystem for Optical Communication Demonstrator

    Science.gov (United States)

    Racho, C.; Portillo, A.

    1998-01-01

    The Optical Communications Demonstrator (OCD) is a laboratory-based lasercom demonstration terminal designed to validate several key technologies, including beacon acquisition, high bandwidth tracking, precision bearn pointing, and point-ahead compensation functions. It has been under active development over the past few years. The instrument uses a CCD array detector for both spatial acquisition and high-bandwidth tracking, and a fiber coupled laser transmitter. The array detector tracking concept provides wide field-of-view acquisition and permits effective platform jitter compensation and point-ahead control using only one steering mirror. This paper describes the detailed design and characterization of the digital control loop system which includes the Fast Steering Mirror (FSM), the CCD image tracker, and the associated electronics. The objective is to improve the overall system performance using laboratory measured data. The. design of the digital control loop is based on a linear time invariant open loop model. The closed loop performance is predicted using the theoretical model. With the digital filter programmed into the OCD control software, data is collected to verify the predictions. This paper presents the results of the, system modeling and performance analysis. It has been shown that measurement data closely matches theoretical predictions. An important part of the laser communication experiment is the ability of FSM to track the laser beacon within the. required tolerances. The pointing must be maintained to an accuracy that is much smaller than the transmit signal beamwidth. For an earth orbit distance, the system must be able to track the receiving station to within a few microradians. The failure. to do so will result in a severely degraded system performance.

  16. A Novel and Efficient Hardware Implementation of Scalar Point Multiplier

    Directory of Open Access Journals (Sweden)

    M. Masoumi

    2012-12-01

    Full Text Available A new and highly efficient architecture for elliptic curve scalar point multiplication is presented. To achieve the maximum architectural and timing improvements we have reorganized and reordered the critical path of the Lopez-Dahab scalar point multiplication architecture such that logic structures are implemented in parallel and operations in the critical path are diverted to noncritical paths. The results we obtained show that with G = 55 our proposed design is able to compute GF(2163 elliptic curve scalar multiplication in 9.6 μs with the maximum achievable frequency of 250 MHz on Xilinx Virtex-4 (XC4VLX200, where G is the digit size of the underlying digit-serial finite field multiplier. Another implementation variant for less resource consumption is also proposed. With G=33, the design performs the same operation in 11.6 μs at 263 MHz on the same platform. The results of synthesis show that in the first implementation 17929 slices or 20% of the chip area is occupied which makes it suitable for speed critical cryptographic applications while in the second implementation 14203 slices or 16% of the chip area is utilized which makes it suitable for applications that may require speed-area trade-off. The new design shows superior performance compared to the previously reported designs.

  17. The ARIES-I high-field-tokamak reactor: Design-point determination and parametric studies

    International Nuclear Information System (INIS)

    Miller, R.L.

    1989-01-01

    The multi-institutional ARIES study has examined the physics, technology, safety, and economic issues associated with the conceptual design of a tokamak magnetic-fusion reactor. The ARIES-I variant envisions a DT-fueled device based on advanced superconducting coil, blanket, and power-conversion technologies and a modest extrapolation of existing tokamak physics. A comprehensive systems and trade study has been conducted as an integral and ongoing part of the reactor assessment in order to identify an acceptable design point to be subjected to detailed analysis and integration as well as to characterize the ARIES-I operating space. Results of parametric studies leading to the identification of such a design point are presented. 15 refs., 6 figs., 2 tabs

  18. Designing DOKK1 from a child’s point of view

    DEFF Research Database (Denmark)

    Geert Jensen, Birgitte; Borup Lynggaard, Aviaja

    2013-01-01

    fun for families in the library? • How can play help to promote interaction and communication? The students worked with the space in Dokk1 as the “third place”, which is identified by Oldenburg (1999) as “great good places”, being public places on neutral ground where people can gather and interact......Designing DOKK1 from a child’s point of view By Aviaja Borup Lynggaard & Birgitte Geert Jensen This poster presents a design case of collaborative innovation between design students from Aarhus School of Architecture and pupils from the public school, Samsøgades School in Aarhus, facilitated...... by the research project Kids n’Tweens Lifestyle. The scope of collaborating was to design the content for DOKK1, the new Mediaspace center in Aarhus, where design students took offset from the children’s world in a creative workshop as inspiration for the final design proposals. The task was carried out...

  19. Multiple ECG Fiducial Points-Based Random Binary Sequence Generation for Securing Wireless Body Area Networks.

    Science.gov (United States)

    Zheng, Guanglou; Fang, Gengfa; Shankaran, Rajan; Orgun, Mehmet A; Zhou, Jie; Qiao, Li; Saleem, Kashif

    2017-05-01

    Generating random binary sequences (BSes) is a fundamental requirement in cryptography. A BS is a sequence of N bits, and each bit has a value of 0 or 1. For securing sensors within wireless body area networks (WBANs), electrocardiogram (ECG)-based BS generation methods have been widely investigated in which interpulse intervals (IPIs) from each heartbeat cycle are processed to produce BSes. Using these IPI-based methods to generate a 128-bit BS in real time normally takes around half a minute. In order to improve the time efficiency of such methods, this paper presents an ECG multiple fiducial-points based binary sequence generation (MFBSG) algorithm. The technique of discrete wavelet transforms is employed to detect arrival time of these fiducial points, such as P, Q, R, S, and T peaks. Time intervals between them, including RR, RQ, RS, RP, and RT intervals, are then calculated based on this arrival time, and are used as ECG features to generate random BSes with low latency. According to our analysis on real ECG data, these ECG feature values exhibit the property of randomness and, thus, can be utilized to generate random BSes. Compared with the schemes that solely rely on IPIs to generate BSes, this MFBSG algorithm uses five feature values from one heart beat cycle, and can be up to five times faster than the solely IPI-based methods. So, it achieves a design goal of low latency. According to our analysis, the complexity of the algorithm is comparable to that of fast Fourier transforms. These randomly generated ECG BSes can be used as security keys for encryption or authentication in a WBAN system.

  20. Multiple spacecraft configuration designs for coordinated flight missions

    Science.gov (United States)

    Fumenti, Federico; Theil, Stephan

    2018-06-01

    Coordinated flight allows the replacement of a single monolithic spacecraft with multiple smaller ones, based on the principle of distributed systems. According to the mission objectives and to ensure a safe relative motion, constraints on the relative distances need to be satisfied. Initially, differential perturbations are limited by proper orbit design. Then, the induced differential drifts can be properly handled through corrective maneuvers. In this work, several designs are surveyed, defining the initial configuration of a group of spacecraft while counteracting the differential perturbations. For each of the investigated designs, focus is placed upon the number of deployable spacecraft and on the possibility to ensure safe relative motion through station keeping of the initial configuration, with particular attention to the required Δ V budget and the constraints violations.

  1. Visualizing Uncertainty of Point Phenomena by Redesigned Error Ellipses

    Science.gov (United States)

    Murphy, Christian E.

    2018-05-01

    Visualizing uncertainty remains one of the great challenges in modern cartography. There is no overarching strategy to display the nature of uncertainty, as an effective and efficient visualization depends, besides on the spatial data feature type, heavily on the type of uncertainty. This work presents a design strategy to visualize uncertainty con-nected to point features. The error ellipse, well-known from mathematical statistics, is adapted to display the uncer-tainty of point information originating from spatial generalization. Modified designs of the error ellipse show the po-tential of quantitative and qualitative symbolization and simultaneous point based uncertainty symbolization. The user can intuitively depict the centers of gravity, the major orientation of the point arrays as well as estimate the ex-tents and possible spatial distributions of multiple point phenomena. The error ellipse represents uncertainty in an intuitive way, particularly suitable for laymen. Furthermore it is shown how applicable an adapted design of the er-ror ellipse is to display the uncertainty of point features originating from incomplete data. The suitability of the error ellipse to display the uncertainty of point information is demonstrated within two showcases: (1) the analysis of formations of association football players, and (2) uncertain positioning of events on maps for the media.

  2. Design of clinical trials involving multiple hypothesis tests with a common control.

    Science.gov (United States)

    Schou, I Manjula; Marschner, Ian C

    2017-07-01

    Randomized clinical trials comparing several treatments to a common control are often reported in the medical literature. For example, multiple experimental treatments may be compared with placebo, or in combination therapy trials, a combination therapy may be compared with each of its constituent monotherapies. Such trials are typically designed using a balanced approach in which equal numbers of individuals are randomized to each arm, however, this can result in an inefficient use of resources. We provide a unified framework and new theoretical results for optimal design of such single-control multiple-comparator studies. We consider variance optimal designs based on D-, A-, and E-optimality criteria, using a general model that allows for heteroscedasticity and a range of effect measures that include both continuous and binary outcomes. We demonstrate the sensitivity of these designs to the type of optimality criterion by showing that the optimal allocation ratios are systematically ordered according to the optimality criterion. Given this sensitivity to the optimality criterion, we argue that power optimality is a more suitable approach when designing clinical trials where testing is the objective. Weighted variance optimal designs are also discussed, which, like power optimal designs, allow the treatment difference to play a major role in determining allocation ratios. We illustrate our methods using two real clinical trial examples taken from the medical literature. Some recommendations on the use of optimal designs in single-control multiple-comparator trials are also provided. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. A Fixed Point VHDL Component Library for a High Efficiency Reconfigurable Radio Design Methodology

    Science.gov (United States)

    Hoy, Scott D.; Figueiredo, Marco A.

    2006-01-01

    Advances in Field Programmable Gate Array (FPGA) technologies enable the implementation of reconfigurable radio systems for both ground and space applications. The development of such systems challenges the current design paradigms and requires more robust design techniques to meet the increased system complexity. Among these techniques is the development of component libraries to reduce design cycle time and to improve design verification, consequently increasing the overall efficiency of the project development process while increasing design success rates and reducing engineering costs. This paper describes the reconfigurable radio component library developed at the Software Defined Radio Applications Research Center (SARC) at Goddard Space Flight Center (GSFC) Microwave and Communications Branch (Code 567). The library is a set of fixed-point VHDL components that link the Digital Signal Processing (DSP) simulation environment with the FPGA design tools. This provides a direct synthesis path based on the latest developments of the VHDL tools as proposed by the BEE VBDL 2004 which allows for the simulation and synthesis of fixed-point math operations while maintaining bit and cycle accuracy. The VHDL Fixed Point Reconfigurable Radio Component library does not require the use of the FPGA vendor specific automatic component generators and provide a generic path from high level DSP simulations implemented in Mathworks Simulink to any FPGA device. The access to the component synthesizable, source code provides full design verification capability:

  4. Design of Xen Hybrid Multiple Police Model

    Science.gov (United States)

    Sun, Lei; Lin, Renhao; Zhu, Xianwei

    2017-10-01

    Virtualization Technology has attracted more and more attention. As a popular open-source virtualization tools, XEN is used more and more frequently. Xsm, XEN security model, has also been widespread concern. The safety status classification has not been established in the XSM, and it uses the virtual machine as a managed object to make Dom0 a unique administrative domain that does not meet the minimum privilege. According to these questions, we design a Hybrid multiple police model named SV_HMPMD that organically integrates multiple single security policy models include DTE,RBAC,BLP. It can fullfill the requirement of confidentiality and integrity for security model and use different particle size to different domain. In order to improve BLP’s practicability, the model introduce multi-level security labels. In order to divide the privilege in detail, we combine DTE with RBAC. In order to oversize privilege, we limit the privilege of domain0.

  5. Multiple types of motives don't multiply the motivation of West Point cadets.

    Science.gov (United States)

    Wrzesniewski, Amy; Schwartz, Barry; Cong, Xiangyu; Kane, Michael; Omar, Audrey; Kolditz, Thomas

    2014-07-29

    Although people often assume that multiple motives for doing something will be more powerful and effective than a single motive, research suggests that different types of motives for the same action sometimes compete. More specifically, research suggests that instrumental motives, which are extrinsic to the activities at hand, can weaken internal motives, which are intrinsic to the activities at hand. We tested whether holding both instrumental and internal motives yields negative outcomes in a field context in which various motives occur naturally and long-term educational and career outcomes are at stake. We assessed the impact of the motives of over 10,000 West Point cadets over the period of a decade on whether they would become commissioned officers, extend their officer service beyond the minimum required period, and be selected for early career promotions. For each outcome, motivation internal to military service itself predicted positive outcomes; a relationship that was negatively affected when instrumental motives were also in evidence. These results suggest that holding multiple motives damages persistence and performance in educational and occupational contexts over long periods of time.

  6. Metal food packaging design based on hazard analysis critical control point (HACCP system in canned food safety

    Directory of Open Access Journals (Sweden)

    Li Xingyi

    2016-06-01

    Full Text Available This study aims to design metal food packaging with hazard analysis critical control point (HACCP. First, theory of HACCP was introduced in detail. Taking empty cans provided by Wuxi Huapeng Food Packaging Company as an example, we studied migration of bisphenol compounds in coating of food can to food stimulant. Moreover, packaging design of luncheon meat can was taken as an example to confirm whether HACCP system could effectively control migration of phenolic substance. Results demonstrated that, coating of such empty were more likely to contain multiple bisphenol compounds such as bisphenol A (BPA, and bisphenol A diglycidyl ether (BADGE was considered as the leading bisphenol pollutant; food stimulant of different types, storage temperature and time could all impact migration of bisphenol compounds. HACCP system was proved to be effective in controlling hazards of phenolic substance in luncheon meat can and could reduce various phenolic substance indexes to an acceptable range. Therefore, HACCP can control migration of phenolic substance and recontamination of food and thus ensure food safety.

  7. Bridges between multiple-point geostatistics and texture synthesis: Review and guidelines for future research

    Science.gov (United States)

    Mariethoz, Gregoire; Lefebvre, Sylvain

    2014-05-01

    Multiple-Point Simulations (MPS) is a family of geostatistical tools that has received a lot of attention in recent years for the characterization of spatial phenomena in geosciences. It relies on the definition of training images to represent a given type of spatial variability, or texture. We show that the algorithmic tools used are similar in many ways to techniques developed in computer graphics, where there is a need to generate large amounts of realistic textures for applications such as video games and animated movies. Similarly to MPS, these texture synthesis methods use training images, or exemplars, to generate realistic-looking graphical textures. Both domains of multiple-point geostatistics and example-based texture synthesis present similarities in their historic development and share similar concepts. These disciplines have however remained separated, and as a result significant algorithmic innovations in each discipline have not been universally adopted. Texture synthesis algorithms present drastically increased computational efficiency, patterns reproduction and user control. At the same time, MPS developed ways to condition models to spatial data and to produce 3D stochastic realizations, which have not been thoroughly investigated in the field of texture synthesis. In this paper we review the possible links between these disciplines and show the potential and limitations of using concepts and approaches from texture synthesis in MPS. We also provide guidelines on how recent developments could benefit both fields of research, and what challenges remain open.

  8. Star Tracker Based ATP System Conceptual Design and Pointing Accuracy Estimation

    Science.gov (United States)

    Orfiz, Gerardo G.; Lee, Shinhak

    2006-01-01

    A star tracker based beaconless (a.k.a. non-cooperative beacon) acquisition, tracking and pointing concept for precisely pointing an optical communication beam is presented as an innovative approach to extend the range of high bandwidth (> 100 Mbps) deep space optical communication links throughout the solar system and to remove the need for a ground based high power laser as a beacon source. The basic approach for executing the ATP functions involves the use of stars as the reference sources from which the attitude knowledge is obtained and combined with high bandwidth gyroscopes for propagating the pointing knowledge to the beam pointing mechanism. Details of the conceptual design are presented including selection of an orthogonal telescope configuration and the introduction of an optical metering scheme to reduce misalignment error. Also, estimates are presented that demonstrate that aiming of the communications beam to the Earth based receive terminal can be achieved with a total system pointing accuracy of better than 850 nanoradians (3 sigma) from anywhere in the solar system.

  9. Assisting People with Multiple Disabilities by Improving Their Computer Pointing Efficiency with an Automatic Target Acquisition Program

    Science.gov (United States)

    Shih, Ching-Hsiang; Shih, Ching-Tien; Peng, Chin-Ling

    2011-01-01

    This study evaluated whether two people with multiple disabilities would be able to improve their pointing performance through an Automatic Target Acquisition Program (ATAP) and a newly developed mouse driver (i.e. a new mouse driver replaces standard mouse driver, and is able to monitor mouse movement and intercept click action). Initially, both…

  10. Higher moments of net kaon multiplicity distributions at RHIC energies for the search of QCD Critical Point at STAR

    Directory of Open Access Journals (Sweden)

    Sarkar Amal

    2013-11-01

    Full Text Available In this paper we report the measurements of the various moments mean (M, standard deviation (σ skewness (S and kurtosis (κ of the net-Kaon multiplicity distribution at midrapidity from Au+Au collisions at √sNN = 7.7 to 200 GeV in the STAR experiment at RHIC in an effort to locate the critical point in the QCD phase diagram. These moments and their products are related to the thermodynamic susceptibilities of conserved quantities such as net baryon number, net charge, and net strangeness as also to the correlation length of the system. A non-monotonic behavior of these variable indicate the presence of the critical point. In this work we also present the moments products Sσ, κσ2 of net-Kaon multiplicity distribution as a function of collision centrality and energies. The energy and the centrality dependence of higher moments of net-Kaons and their products have been compared with it0s Poisson expectation and with simulations from AMPT which does not include the critical point. From the measurement at all seven available beam energies, we find no evidence for a critical point in the QCD phase diagram for √sNN below 200 GeV.

  11. Extremely sensitive multiple sensing ring PCF sensor for lower indexed chemical detection

    Directory of Open Access Journals (Sweden)

    Veerpal Kaur

    2017-09-01

    Full Text Available In this article, we have designed and analysed a photonic crystal fiber with multiple sensing ring in core for chemical and biochemical sensing applications. In this proposed design, three and four sensing ring describe in core which offers remarkable high sensitivity and spiral cladding pattern confines large fraction of power in core region and thus reduce the overall confinement loss. This novel proposed model exhibits simultaneously ultra high relative sensitivity 95.40%, 93.13% and minimum confinement loss 7.108×10−08, 2.47×10−08dB/km for four and three ring pattern. These sensing rings are filled with different sensing liquid. Multiple sensing rings as compared to multiple air holes are desirable feature from fabrication point of view. This proposed PCF design overcomes some experimental challenge such as PCF probe needs some displacement after filling the sensing liquid. These uniform circular sensing rings around the solid core overcome the losses and support better evanescent field matter interaction for sensing application. Multiple sensing rings as compared to multiple tiny air holes are desirable feature from fabrication point of view.

  12. Design of Wireless Point of Sale Based on ZigBee Technology

    Directory of Open Access Journals (Sweden)

    Xiaoning Jiang

    2014-02-01

    Full Text Available With the rapid development of Point of Sale technology and modern communication technology, financial Point of Sale terminal system has been started from wired to wireless. Wireless payment technology can used where can’t rely on or even no cable network. As one of the most important technologies in the information era, Wireless Sensor Network has been widely used in banking business and other various modem business fields. This paper describes a kind of simple portable Point of Sale terminal based on the ZigBee wireless network 1, which is a low power, low cost, flexible, safe and reliable network. This Point of Sale system can be applied gas stations, liquefied petroleum gas stations and other complex sales environment, and it improves safety of gas station and personnel safety. Simple and user-friendly, this formula design and optimization method greatly improves efficiency and thus has much value for practical application.

  13. Simultaneous colour visualizations of multiple ALS point cloud attributes for land cover and vegetation analysis

    Science.gov (United States)

    Zlinszky, András; Schroiff, Anke; Otepka, Johannes; Mandlburger, Gottfried; Pfeifer, Norbert

    2014-05-01

    LIDAR point clouds hold valuable information for land cover and vegetation analysis, not only in the spatial distribution of the points but also in their various attributes. However, LIDAR point clouds are rarely used for visual interpretation, since for most users, the point cloud is difficult to interpret compared to passive optical imagery. Meanwhile, point cloud viewing software is available allowing interactive 3D interpretation, but typically only one attribute at a time. This results in a large number of points with the same colour, crowding the scene and often obscuring detail. We developed a scheme for mapping information from multiple LIDAR point attributes to the Red, Green, and Blue channels of a widely used LIDAR data format, which are otherwise mostly used to add information from imagery to create "photorealistic" point clouds. The possible combinations of parameters are therefore represented in a wide range of colours, but relative differences in individual parameter values of points can be well understood. The visualization was implemented in OPALS software, using a simple and robust batch script, and is viewer independent since the information is stored in the point cloud data file itself. In our case, the following colour channel assignment delivered best results: Echo amplitude in the Red, echo width in the Green and normalized height above a Digital Terrain Model in the Blue channel. With correct parameter scaling (but completely without point classification), points belonging to asphalt and bare soil are dark red, low grassland and crop vegetation are bright red to yellow, shrubs and low trees are green and high trees are blue. Depending on roof material and DTM quality, buildings are shown from red through purple to dark blue. Erroneously high or low points, or points with incorrect amplitude or echo width usually have colours contrasting from terrain or vegetation. This allows efficient visual interpretation of the point cloud in planar

  14. Effect of fuel fabrication parameters on performance- designer's point of view

    International Nuclear Information System (INIS)

    Prasad, P.N.; Ravi, M.; Soni, R.; Bajaj, S.S.; Bhardwaj, S.A.

    2004-01-01

    The fuel bundle performance in reactor depends upon the material properties, dimensions of the different components and their inter-compatibility. This paper brings out the fuel parameters required to be optimised to achieve better fuel reliability, operational flexibility, safety and economics from the designer point of view

  15. Sonification of reference markers for auditory graphs: effects on non-visual point estimation tasks

    Directory of Open Access Journals (Sweden)

    Oussama Metatla

    2016-04-01

    Full Text Available Research has suggested that adding contextual information such as reference markers to data sonification can improve interaction with auditory graphs. This paper presents results of an experiment that contributes to quantifying and analysing the extent of such benefits for an integral part of interacting with graphed data: point estimation tasks. We examine three pitch-based sonification mappings; pitch-only, one-reference, and multiple-references that we designed to provide information about distance from an origin. We assess the effects of these sonifications on users’ performances when completing point estimation tasks in a between-subject experimental design against visual and speech control conditions. Results showed that the addition of reference tones increases users accuracy with a trade-off for task completion times, and that the multiple-references mapping is particularly effective when dealing with points that are positioned at the midrange of a given axis.

  16. [Multiple time scales analysis of spatial differentiation characteristics of non-point source nitrogen loss within watershed].

    Science.gov (United States)

    Liu, Mei-bing; Chen, Xing-wei; Chen, Ying

    2015-07-01

    Identification of the critical source areas of non-point source pollution is an important means to control the non-point source pollution within the watershed. In order to further reveal the impact of multiple time scales on the spatial differentiation characteristics of non-point source nitrogen loss, a SWAT model of Shanmei Reservoir watershed was developed. Based on the simulation of total nitrogen (TN) loss intensity of all 38 subbasins, spatial distribution characteristics of nitrogen loss and critical source areas were analyzed at three time scales of yearly average, monthly average and rainstorms flood process, respectively. Furthermore, multiple linear correlation analysis was conducted to analyze the contribution of natural environment and anthropogenic disturbance on nitrogen loss. The results showed that there were significant spatial differences of TN loss in Shanmei Reservoir watershed at different time scales, and the spatial differentiation degree of nitrogen loss was in the order of monthly average > yearly average > rainstorms flood process. TN loss load mainly came from upland Taoxi subbasin, which was identified as the critical source area. At different time scales, land use types (such as farmland and forest) were always the dominant factor affecting the spatial distribution of nitrogen loss, while the effect of precipitation and runoff on the nitrogen loss was only taken in no fertilization month and several processes of storm flood at no fertilization date. This was mainly due to the significant spatial variation of land use and fertilization, as well as the low spatial variability of precipitation and runoff.

  17. Sequential, Multiple Assignment, Randomized Trial Designs in Immuno-oncology Research.

    Science.gov (United States)

    Kidwell, Kelley M; Postow, Michael A; Panageas, Katherine S

    2018-02-15

    Clinical trials investigating immune checkpoint inhibitors have led to the approval of anti-CTLA-4 (cytotoxic T-lymphocyte antigen-4), anti-PD-1 (programmed death-1), and anti-PD-L1 (PD-ligand 1) drugs by the FDA for numerous tumor types. In the treatment of metastatic melanoma, combinations of checkpoint inhibitors are more effective than single-agent inhibitors, but combination immunotherapy is associated with increased frequency and severity of toxicity. There are questions about the use of combination immunotherapy or single-agent anti-PD-1 as initial therapy and the number of doses of either approach required to sustain a response. In this article, we describe a novel use of sequential, multiple assignment, randomized trial (SMART) design to evaluate immune checkpoint inhibitors to find treatment regimens that adapt within an individual based on intermediate response and lead to the longest overall survival. We provide a hypothetical example SMART design for BRAF wild-type metastatic melanoma as a framework for investigating immunotherapy treatment regimens. We compare implementing a SMART design to implementing multiple traditional randomized clinical trials. We illustrate the benefits of a SMART over traditional trial designs and acknowledge the complexity of a SMART. SMART designs may be an optimal way to find treatment strategies that yield durable response, longer survival, and lower toxicity. Clin Cancer Res; 24(4); 730-6. ©2017 AACR . ©2017 American Association for Cancer Research.

  18. Building a Better Mousetrap: How Design-Based Research Was Used to Improve Homemade PowerPoint Games

    Science.gov (United States)

    Siko, Jason P.; Barbour, Michael K.

    2016-01-01

    This paper is a review of a three-cycle, design-based research study that explored the relationship between the pedagogical research and the actual implementation of a game design project using Microsoft PowerPoint. Much of the initial literature on using homemade PowerPoint games showed no significant improvement in test scores when students…

  19. LSHSIM: A Locality Sensitive Hashing based method for multiple-point geostatistics

    Science.gov (United States)

    Moura, Pedro; Laber, Eduardo; Lopes, Hélio; Mesejo, Daniel; Pavanelli, Lucas; Jardim, João; Thiesen, Francisco; Pujol, Gabriel

    2017-10-01

    Reservoir modeling is a very important task that permits the representation of a geological region of interest, so as to generate a considerable number of possible scenarios. Since its inception, many methodologies have been proposed and, in the last two decades, multiple-point geostatistics (MPS) has been the dominant one. This methodology is strongly based on the concept of training image (TI) and the use of its characteristics, which are called patterns. In this paper, we propose a new MPS method that combines the application of a technique called Locality Sensitive Hashing (LSH), which permits to accelerate the search for patterns similar to a target one, with a Run-Length Encoding (RLE) compression technique that speeds up the calculation of the Hamming similarity. Experiments with both categorical and continuous images show that LSHSIM is computationally efficient and produce good quality realizations. In particular, for categorical data, the results suggest that LSHSIM is faster than MS-CCSIM, one of the state-of-the-art methods.

  20. Bilevel formulation of a policy design problem considering multiple objectives and incomplete preferences

    Science.gov (United States)

    Hawthorne, Bryant; Panchal, Jitesh H.

    2014-07-01

    A bilevel optimization formulation of policy design problems considering multiple objectives and incomplete preferences of the stakeholders is presented. The formulation is presented for Feed-in-Tariff (FIT) policy design for decentralized energy infrastructure. The upper-level problem is the policy designer's problem and the lower-level problem is a Nash equilibrium problem resulting from market interactions. The policy designer has two objectives: maximizing the quantity of energy generated and minimizing policy cost. The stakeholders decide on quantities while maximizing net present value and minimizing capital investment. The Nash equilibrium problem in the presence of incomplete preferences is formulated as a stochastic linear complementarity problem and solved using expected value formulation, expected residual minimization formulation, and the Monte Carlo technique. The primary contributions in this article are the mathematical formulation of the FIT policy, the extension of computational policy design problems to multiple objectives, and the consideration of incomplete preferences of stakeholders for policy design problems.

  1. Coexistence of different vacua in the effective quantum field theory and multiple point principle

    International Nuclear Information System (INIS)

    Volovik, G.E.

    2004-01-01

    According to the multiple point principle our Universe in on the coexistence curve of two or more phases of the quantum vacuum. The coexistence of different quantum vacua can be regulated by the exchange of the global fermionic charges between the vacua. If the coexistence is regulated by the baryonic charge, all the coexisting vacua exhibit the baryonic asymmetry. Due to the exchange of the baryonic charge between the vacuum and matter which occurs above the electroweak transition, the baryonic asymmetry of the vacuum induces the baryonic asymmetry of matter in our Standard-Model phase of the quantum vacuum [ru

  2. Critical point predication device

    International Nuclear Information System (INIS)

    Matsumura, Kazuhiko; Kariyama, Koji.

    1996-01-01

    An operation for predicting a critical point by using a existent reverse multiplication method has been complicated, and an effective multiplication factor could not be plotted directly to degrade the accuracy for the prediction. The present invention comprises a detector counting memory section for memorizing the counting sent from a power detector which monitors the reactor power, a reverse multiplication factor calculation section for calculating the reverse multiplication factor based on initial countings and current countings of the power detector, and a critical point prediction section for predicting the criticality by the reverse multiplication method relative to effective multiplication factors corresponding to the state of the reactor core previously determined depending on the cases. In addition, a reactor core characteristic calculation section is added for analyzing an effective multiplication factor depending on the state of the reactor core. Then, if the margin up to the criticality is reduced to lower than a predetermined value during critical operation, an alarm is generated to stop the critical operation when generation of a period of more than a predetermined value predicted by succeeding critical operation. With such procedures, forecasting for the critical point can be easily predicted upon critical operation to greatly mitigate an operator's burden and improve handling for the operation. (N.H.)

  3. Monte Carlo full-waveform inversion of crosshole GPR data using multiple-point geostatistical a priori information

    DEFF Research Database (Denmark)

    Cordua, Knud Skou; Hansen, Thomas Mejer; Mosegaard, Klaus

    2012-01-01

    We present a general Monte Carlo full-waveform inversion strategy that integrates a priori information described by geostatistical algorithms with Bayesian inverse problem theory. The extended Metropolis algorithm can be used to sample the a posteriori probability density of highly nonlinear...... inverse problems, such as full-waveform inversion. Sequential Gibbs sampling is a method that allows efficient sampling of a priori probability densities described by geostatistical algorithms based on either two-point (e.g., Gaussian) or multiple-point statistics. We outline the theoretical framework......) Based on a posteriori realizations, complicated statistical questions can be answered, such as the probability of connectivity across a layer. (3) Complex a priori information can be included through geostatistical algorithms. These benefits, however, require more computing resources than traditional...

  4. Cross-Layer Design for Two-Way Relaying Networks with Multiple Antennas

    Directory of Open Access Journals (Sweden)

    zhuo wu

    2015-10-01

    Full Text Available In this paper, we developed a cross-layer design for two-way relaying (TWR networks with multiple antennas, where two single antenna source nodes exchange information with the aid of one multiple antenna relay node. The proposed cross-layer design considers adaptive modulation (AM and space-time block coding (STBC at the physical layer with an automatic repeat request (ARQ protocol at the data link layer, in order to maximize the spectral efficiency under specific delay and packet error ratio (PER constraints. An MMSE-interference cancellation (IC receiver is employed at the relay node, to remove the interference in the fist phase of the TWR transmission. The transmission mode is updated for each phase of the TWR transmission on a frame-by-frame basis, to match the time-varying channel conditions and exploit the system performance and throughput gain. Simulation results show that retransmission at the data link layer could alleviate rigorous error-control requirements at the physical layer, and thereby allows higher data transmission. As a result, cross-layer design helps to achieve considerable system spectral efficiency gain for TWR networks, compared to those without cross-layer design.

  5. The guinea pig maximization test--with a multiple dose design

    DEFF Research Database (Denmark)

    Andersen, Klaus Ejner; Vølund, A; Frankild, S

    1995-01-01

    The guinea pig maximization test (GPMT) is usually performed with one moderately irritant induction dose of the allergen and gives a qualitative assessment-hazard identification-of the allergenicity of the chemical. We refined the GPMT by applying a multiple dose design and used 30 guinea pigs in...

  6. The guinea pig maximization test--with a multiple dose design

    DEFF Research Database (Denmark)

    Andersen, Klaus Ejner; Vølund, A; Frankild, S

    1995-01-01

    The guinea pig maximization test (GPMT) is usually performed with one moderately irritant induction dose of the allergen and gives a qualitative assessment-hazard identification-of the allergenicity of the chemical. We refined the GPMT by applying a multiple dose design and used 30 guinea pigs...

  7. Near-maximum-power-point-operation (nMPPO) design of photovoltaic power generation system

    Energy Technology Data Exchange (ETDEWEB)

    Huang, B.J.; Sun, F.S.; Ho, R.W. [Department of Mechanical Engineering, National Taiwan University, Taipei 106, Taiwan (China)

    2006-08-15

    The present study proposes a PV system design, called 'near-maximum power-point-operation' (nMPPO) that can maintain the performance very close to PV system with MPPT (maximum-power-point tracking) but eliminate hardware of the MPPT. The concept of nMPPO is to match the design of battery bank voltage V{sub set} with the MPP (maximum-power point) of the PV module based on an analysis using meteorological data. Three design methods are used in the present study to determine the optimal V{sub set}. The analytical results show that nMPPO is feasible and the optimal V{sub set} falls in the range 13.2-15.0V for MSX60 PV module. The long-term performance simulation shows that the overall nMPPO efficiency {eta}{sub nMPPO} is higher than 94%. Two outdoor field tests were carried out in the present study to verify the design of nMPPO. The test results for a single PV module (60Wp) indicate that the nMPPO efficiency {eta}{sub nMPPO} is mostly higher than 93% at various PV temperature T{sub pv}. Another long-term field test of 1kWp PV array using nMPPO shows that the power generation using nMPPO is almost identical with MPPT at various weather conditions and T{sub pv} variation from 24{sup o}C to 70{sup o}C. (author)

  8. Under digital fluoroscopic guidance multiple-point injection with absolute alcohol and pinyangmycin for the treatment of superficial venous malformations

    International Nuclear Information System (INIS)

    Yang Ming; Xiao Gang; Peng Youlin

    2010-01-01

    Objective: to investigate the therapeutic efficacy of multiple-point injection with absolute alcohol and pinyangmycin under digital fluoroscopic guidance for superficial venous malformations. Methods: By using a disposal venous transfusion needle the superficial venous malformation was punctured and then contrast media lohexol was injected in to visualize the tumor body, which was followed by the injection of ethanol and pinyangmycin when the needle was confirmed in the correct position. The procedure was successfully performed in 31 patients. The clinical results were observed and analyzed. Results: After one treatment complete cure was achieved in 21 cases and marked effect was obtained in 8 cases, with a total effectiveness of 93.5%. Conclusion: Multiple-point injection with ethanol and pinyangmycin under digital fluoroscopic guidance is an effective and safe technique for the treatment of superficial venous malformations, especially for the lesions that are deeply located and ill-defined. (authors)

  9. VNM: An R Package for Finding Multiple-Objective Optimal Designs for the 4-Parameter Logistic Model

    OpenAIRE

    Hyun, Seung Won; Wong, Weng Kee; Yang, Yarong

    2018-01-01

    A multiple-objective optimal design is useful for dose-response studies because it can incorporate several objectives at the design stage. Objectives can be of varying interests and a properly constructed multiple-objective optimal design can provide user-specified efficiencies, delivering higher efficiencies for the more important objectives. In this work, we introduce the VNM package written in R for finding 3-objective locally optimal designs for the 4-parameter logistic (4PL) model widely...

  10. Design and Development of A Three-Point Auto Hitch Dynamometer for An Agricultural Tractor

    Directory of Open Access Journals (Sweden)

    A. F. Kheiralla

    2017-12-01

    Full Text Available This paper describes the design, development and calibration of a three-point auto hitch dynamometer for measuring the horizontal and vertical forces that existed at the three-point hitch of an agricultural tractor.  The design concept of the dynamometer was based on an instrumented inverted U frame assembly that was mounted between tractor links and implement. The design incorporates for both lower point hitch spread and mast height adjustments, and quick hitch capability in accordance with category 1 and II three-point hitch system.  The force sensing elements were comprised of three steel extended octagonal ring transducers that were located between the inverted U frame and hook brackets.  Electrical resistance strain gauges were mounted on the extended octagonal ring transducer at strain angle nodes to independently monitor strains that were proportional to the horizontal and vertical forces at the ring center. Each transducer was designed for maximum horizontal and vertical forces of 25 kN and 10 kN at measurement mean sensitivities of 25.19 µStrain/kN and 25.60 µStrain/kN, respectively. However, the complete dynamometer has been designed to measure the maximum resultant horizontal and vertical forces of 50 kN and 20 kN, respectively.  Field demonstration tests on the dynamometer and data acquisition system showed that they were able to function effectively as intended.  The data acquisition system was able to successfully scan and record the dynamometer signals as programmed.  This dynamometer was part of the complete instrumentation system to be developed onboard a Massey Ferguson 3060 tractor for the generation of a comprehensive database on the power and energy requirements of the tractor and its working implement in the field.

  11. BSDB: A New Consistent Designation Scheme for Identifying Objects in Binary and Multiple Stars

    Directory of Open Access Journals (Sweden)

    Kovaleva D. A.

    2015-06-01

    Full Text Available The new consistent scheme for designation of objects in binary and multiple systems, BSDB, is described. It was developed in the frame of the Binary star DataBase, BDB (http://www.inasan.ru, due to necessity of a unified and consistent system for designation of objects in the database, and the name of the designation scheme was derived from that of the database. The BSDB scheme covers all types of observational data. Three classes of objects introduced within the BSDB nomenclature provide correct links between objects and data, what is especially important for complex multiple stellar systems. The final stage of establishing the BSDB scheme is compilation of the Identification List of Binaries, ILB, where all known objects in binary and multiple stars are presented with their BSDB identifiers along with identifiers according to major catalogues and lists.

  12. Influence of the size of facets on point focus solar concentrators

    Energy Technology Data Exchange (ETDEWEB)

    Riveros-Rosas, David [Instituto de Geofisica, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Col. Copilco, Coyoacan, CP 04510 DF (Mexico); Sanchez-Gonzalez, Marcelino [Centro Nacional de Energias Renovables, c/Somera 7-9, CP 28026 Madrid (Spain); Arancibia-Bulnes, Camilo A.; Estrada, Claudio A. [Centro de Investigacion en Energia, Universidad Nacional Autonoma de Mexico, Priv. Xochicalco s/n, Morelos (Mexico)

    2011-03-15

    It is a common practice in the development of point focus solar concentrators to use multiple identical reflecting facets, as a practical and economic alternative for the design and construction of large systems. This kind of systems behaves in a different manner than continuous paraboloidal concentrators. A theoretical study is carried out to understand the effect of the size of facets and of their optical errors in multiple facet point focus solar concentrating systems. For this purpose, a ray tracing program was developed based on the convolution technique, in which the brightness distribution of the sun and the optical errors of the reflecting surfaces are considered. The study shows that both the peak of concentration and the optimal focal distance of the system strongly depend on the size of the facets, and on their optical errors. These results are useful to help concentrator developers to have a better understanding of the relationship between manufacturing design restrictions and final optical behavior. (author)

  13. The emergence of designed multiple ligands for neurodegenerative disorders.

    Science.gov (United States)

    Geldenhuys, Werner J; Youdim, Moussa B H; Carroll, Richard T; Van der Schyf, Cornelis J

    2011-09-01

    The incidence of neurodegenerative diseases has seen a constant increase in the global population, and is likely to be the result of extended life expectancy brought about by better health care. Despite this increase in the incidence of neurodegenerative diseases, there has been a dearth in the introduction of new disease-modifying therapies that are approved to prevent or delay the onset of these diseases, or reverse the degenerative processes in brain. Mounting evidence in the peer-reviewed literature shows that the etiopathology of these diseases is extremely complex and heterogeneous, resulting in significant comorbidity and therefore unlikely to be mitigated by any drug acting on a single pathway or target. A recent trend in drug design and discovery is the rational design or serendipitous discovery of novel drug entities with the ability to address multiple drug targets that form part of the complex pathophysiology of a particular disease state. In this review we discuss the rationale for developing such multifunctional drugs (also called designed multiple ligands or DMLs), and why these drug candidates seem to offer better outcomes in many cases compared to single-targeted drugs in pre-clinical studies for neurodegenerative diseases such as Alzheimer's and Parkinson's disease. Examples are drawn from the literature of drug candidates that have already reached the market, some unsuccessful attempts, and others that are still in the drug development pipeline. Copyright © 2011. Published by Elsevier Ltd.

  14. Design optimization of offshore wind farms with multiple types of wind turbines

    DEFF Research Database (Denmark)

    Feng, Ju; Shen, Wen Zhong

    2017-01-01

    Most studies on offshore wind farm design assume a uniform wind farm, which consists of an identical type of wind turbines. In order to further reduce the cost of energy, we investigate the design of non-uniform offshore wind farms, i.e., wind farms with multiple types of wind turbines and hub-he...

  15. PC-based Multiple Information System Interface (PC/MISI) design plan

    Science.gov (United States)

    Dominick, Wayne D. (Editor); Hall, Philip P.

    1985-01-01

    The general design plan for the implementation of a common user interface to multiple remote information systems within a microcomputer-based environment is presented. The intent is to provide a framework for the development of detailed specifications which will be used as guidelines for the actual development of the system.

  16. Free-space optical code-division multiple-access system design

    Science.gov (United States)

    Jeromin, Lori L.; Kaufmann, John E.; Bucher, Edward A.

    1993-08-01

    This paper describes an optical direct-detection multiple access communications system for free-space satellite networks utilizing code-division multiple-access (CDMA) and forward error correction (FEC) coding. System performance is characterized by how many simultaneous users operating at data rate R can be accommodated in a signaling bandwidth W. The performance of two CDMA schemes, optical orthogonal codes (OOC) with FEC and orthogonal convolutional codes (OCC), is calculated and compared to information-theoretic capacity bounds. The calculations include the effects of background and detector noise as well as nonzero transmitter extinction ratio and power imbalance among users. A system design for 10 kbps multiple-access communications between low-earth orbit satellites is given. With near- term receiver technology and representative system losses, a 15 W peak-power transmitter provides 10-6 BER performance with seven interfering users and full moon background in the receiver FOV. The receiver employs an array of discrete wide-area avalanche photodiodes (APD) for wide field of view coverage. Issues of user acquisition and synchronization, implementation technology, and system scalability are also discussed.

  17. Orbit Transfer Vehicle (OTV) advanced expander cycle engine point design study, volume 2

    Science.gov (United States)

    1981-01-01

    The engine requirements are emphasized and include: high specific impulse within a restricted installed length constraint, long life, multiple starts, different thrust levels, and man-rated reliability. The engine operating characteristics and the major component analytical design are summarized.

  18. Design of multiple sequence alignment algorithms on parallel, distributed memory supercomputers.

    Science.gov (United States)

    Church, Philip C; Goscinski, Andrzej; Holt, Kathryn; Inouye, Michael; Ghoting, Amol; Makarychev, Konstantin; Reumann, Matthias

    2011-01-01

    The challenge of comparing two or more genomes that have undergone recombination and substantial amounts of segmental loss and gain has recently been addressed for small numbers of genomes. However, datasets of hundreds of genomes are now common and their sizes will only increase in the future. Multiple sequence alignment of hundreds of genomes remains an intractable problem due to quadratic increases in compute time and memory footprint. To date, most alignment algorithms are designed for commodity clusters without parallelism. Hence, we propose the design of a multiple sequence alignment algorithm on massively parallel, distributed memory supercomputers to enable research into comparative genomics on large data sets. Following the methodology of the sequential progressiveMauve algorithm, we design data structures including sequences and sorted k-mer lists on the IBM Blue Gene/P supercomputer (BG/P). Preliminary results show that we can reduce the memory footprint so that we can potentially align over 250 bacterial genomes on a single BG/P compute node. We verify our results on a dataset of E.coli, Shigella and S.pneumoniae genomes. Our implementation returns results matching those of the original algorithm but in 1/2 the time and with 1/4 the memory footprint for scaffold building. In this study, we have laid the basis for multiple sequence alignment of large-scale datasets on a massively parallel, distributed memory supercomputer, thus enabling comparison of hundreds instead of a few genome sequences within reasonable time.

  19. Design and construction of a point-contact spectroscopy rig with lateral scanning capability

    Energy Technology Data Exchange (ETDEWEB)

    Tortello, M. [Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, Torino 10129 (Italy); Park, W. K., E-mail: wkpark@illinois.edu; Ascencio, C. O.; Saraf, P.; Greene, L. H. [Department of Physics and Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801 (United States)

    2016-06-15

    The design and realization of a cryogenic rig for point-contact spectroscopy measurements in the needle-anvil configuration is presented. Thanks to the use of two piezoelectric nano-positioners, the tip can move along the vertical (z) and horizontal (x) direction and thus the rig is suitable to probe different regions of a sample in situ. Moreover, it can also form double point-contacts on different facets of a single crystal for achieving, e.g., an interferometer configuration for phase-sensitive measurements. For the later purpose, the sample holder can also host a Helmholtz coil for applying a small transverse magnetic field to the junction. A semi-rigid coaxial cable can be easily added for studying the behavior of Josephson junctions under microwave irradiation. The rig can be detached from the probe and thus used with different cryostats. The performance of this new probe has been tested in a Quantum Design PPMS system by conducting point-contact Andreev reflection measurements on Nb thin films over large areas as a function of temperature and magnetic field.

  20. Optimization Algorithms for Calculation of the Joint Design Point in Parallel Systems

    DEFF Research Database (Denmark)

    Enevoldsen, I.; Sørensen, John Dalsgaard

    1992-01-01

    In large structures it is often necessary to estimate the reliability of the system by use of parallel systems. Optimality criteria-based algorithms for calculation of the joint design point in a parallel system are described and efficient active set strategies are developed. Three possible...

  1. Does decision documentation help junior designers rationalize their decisions? A comparative multiple-case study

    NARCIS (Netherlands)

    Heesch, U. van; Avgeriou, P.; Tang, A.

    Software architecture design is challenging, especially for junior software designers. Lacking practice and experience, junior designers need process support in order to make rational architecture decisions. In this paper, we present the results of a comparative multiple-case study conducted to find

  2. Some remarks on the design of HIF current multiplication rings

    International Nuclear Information System (INIS)

    Reich, K.H.

    1983-12-01

    The conceptual design of heavy ion fusion drivers has now reached a state, where the overall approach has become fairly clear. One design features an RF linac plus current and beam multiplication rings. The present remarks concern the assignment of multiturn injection, beam storage and bunching to an optimized number of rings and transport lines, as well as some criteria for their designs. The main parameter constraints are discussed, showing how they can be met, although there is little flexibility at the present stage of understanding and technology. A shortened version of this report is scheduled for presentation at the ''INS International Symposium on Heavy Ion Accelerators and Their Application to Inertial Fusion'' Tokyo, January 23-27 1984. (author)

  3. A quantitative analysis of statistical power identifies obesity end points for improved in vivo preclinical study design.

    Science.gov (United States)

    Selimkhanov, J; Thompson, W C; Guo, J; Hall, K D; Musante, C J

    2017-08-01

    The design of well-powered in vivo preclinical studies is a key element in building the knowledge of disease physiology for the purpose of identifying and effectively testing potential antiobesity drug targets. However, as a result of the complexity of the obese phenotype, there is limited understanding of the variability within and between study animals of macroscopic end points such as food intake and body composition. This, combined with limitations inherent in the measurement of certain end points, presents challenges to study design that can have significant consequences for an antiobesity program. Here, we analyze a large, longitudinal study of mouse food intake and body composition during diet perturbation to quantify the variability and interaction of the key metabolic end points. To demonstrate how conclusions can change as a function of study size, we show that a simulated preclinical study properly powered for one end point may lead to false conclusions based on secondary end points. We then propose the guidelines for end point selection and study size estimation under different conditions to facilitate proper power calculation for a more successful in vivo study design.

  4. Harnessing Multiple Internal Reflections to Design Highly Absorptive Acoustic Metasurfaces

    Science.gov (United States)

    Shen, Chen; Cummer, Steven A.

    2018-05-01

    The rapid development of metasurfaces has enabled numerous intriguing applications with acoustically thin sheets. Here we report the theory and experimental realization of a nonresonant sound-absorbing strategy using metasurfaces by harnessing multiple internal reflections. We theoretically and numerically show that the higher-order diffraction of thin gradient-index metasurfaces is tied to multiple internal reflections inside the unit cells. Highly absorbing acoustic metasurfaces can be realized by enforcing multiple internal reflections together with a small amount of loss. A reflective gradient-index acoustic metasurface is designed based on the theory, and we further experimentally verify the performance using a three-dimensional printed prototype. Measurements show over 99% energy absorption at the peak frequency and a 95% energy absorption bandwidth of around 600 Hz. The proposed mechanism provides an alternative route for sound absorption without the necessity of high absorption of the individual unit cells.

  5. Designing for Children's Collective Music Making

    DEFF Research Database (Denmark)

    Grønbæk, Jens Emil; Jakobsen, Kasper; Petersen, Marianne Graves

    2016-01-01

    Hitmachine empowers children to make music through building physical, shared interactive instruments from Lego MindstormsTM and playing them to a beat. The design rationale for Hitmachine draws upon the collective interaction model, theories of proxemics and F-formations, as well as a framework...... for social interaction. Hitmachine was evaluated during a 4-day workshop where 150 children aged 3-13 engaged with the system. Based on lessons from this workshop we point to key issues to consider when designing for collective music making. This includes designing for multiple access points and spatial...

  6. Nursing Reference Center: a point-of-care resource.

    Science.gov (United States)

    Vardell, Emily; Paulaitis, Gediminas Geddy

    2012-01-01

    Nursing Reference Center is a point-of-care resource designed for the practicing nurse, as well as nursing administrators, nursing faculty, and librarians. Users can search across multiple resources, including topical Quick Lessons, evidence-based care sheets, patient education materials, practice guidelines, and more. Additional features include continuing education modules, e-books, and a new iPhone application. A sample search and comparison with similar databases were conducted.

  7. Mobile Web for Pervasive environments - design webexperiences for multiple mobile devices

    DEFF Research Database (Denmark)

    Hansen, Thomas Riisgaard

    2008-01-01

    In this paper we present an architecture for designing web pages that uses multiple mobile and stationary devices to present web content. The architecture extends standard web technology with a number of functions for expressing how web content might migrate and use multiple displays....... The architecture is developed to support desktop applications, but in this paper we describe how the architecture can be extended to mobile devices by using AJAX technology. The paper also presents an implementation and presents a number of applications for mobile devices developed with this framework....

  8. Design of PH-based accelerated life testing plans under multiple-stress-type

    International Nuclear Information System (INIS)

    Elsayed, E.A.; Zhang Hao

    2007-01-01

    Accelerated life testing (ALT) is used to obtain failure time data quickly under high stress levels in order to predict product life performance under design stress conditions. Most of the previous work on designing ALT plans is focused on the application of a single stress. However, as components or products become more reliable due to technological advances, it becomes more difficult to obtain significant amount of failure data within reasonable amount of time using single stress only. Multiple-stress-type ALTs have been employed as a means of overcoming such difficulties. In this paper, we design optimum multiple-stress-type ALT plans based on the proportional hazards model. The optimum combinations of stresses and their levels are determined such that the variance of the reliability estimate of the product over a specified period of time is minimized. The use of the model is illustrated using numerical example, and sensitivity analysis shows that the resultant optimum ALT plan is robust to the deviation in model parameters

  9. Finite element and node point generation computer programs used for the design of toroidal field coils in tokamak fusion devices

    International Nuclear Information System (INIS)

    Smith, R.A.

    1975-06-01

    The structural analysis of toroidal field coils in Tokamak fusion machines can be performed with the finite element method. This technique has been employed for design evaluations of toroidal field coils on the Princeton Large Torus (PLT), the Poloidal Diverter Experiment (PDX), and the Tokamak Fusion Test Reactor (TFTR). The application of the finite element method can be simplified with computer programs that are used to generate the input data for the finite element code. There are three areas of data input where significant automation can be provided by supplementary computer codes. These concern the definition of geometry by a node point mesh, the definition of the finite elements from the geometric node points, and the definition of the node point force/displacement boundary conditions. The node point forces in a model of a toroidal field coil are computed from the vector cross product of the coil current and the magnetic field. The computer programs named PDXNODE and ELEMENT are described. The program PDXNODE generates the geometric node points of a finite element model for a toroidal field coil. The program ELEMENT defines the finite elements of the model from the node points and from material property considerations. The program descriptions include input requirements, the output, the program logic, the methods of generating complex geometries with multiple runs, computational time and computer compatibility. The output format of PDXNODE and ELEMENT make them compatible with PDXFORC and two general purpose finite element computer codes: (ANSYS) the Engineering Analysis System written by the Swanson Analysis Systems, Inc., and (WECAN) the Westinghouse Electric Computer Analysis general purpose finite element program. The Fortran listings of PDXNODE and ELEMENT are provided

  10. Cost-Based Design and Selection of Point Absorber Devices for the Mediterranean Sea

    Directory of Open Access Journals (Sweden)

    Vincenzo Piscopo

    2018-04-01

    Full Text Available Sea wave energy is one of the most promising renewable sources, even if relevant technology is not mature enough for the global energy market and is not yet competitive if compared with solar, wind and tidal current devices. Particularly, among the variety of wave energy converters developed in the last decade, heaving point absorbers represent one of the most feasible and studied technologies, as shown by the small-scale testing and full-scale prototypes, deployed in the last years throughout the world. Nevertheless, the need for further reduction of the energy production costs requires a specialized design of wave energy converters, accounting for the restraints provided by the power take-off unit and the device operational profile. Hence, actual analysis focuses on a new cost-based design procedure for heaving point absorbers. The device is equipped with a floating buoy with an optional fully submerged mass connected, by means of a tensioned line, to the power take-off unit. It consists of a permanent magnet linear generator, lying on the seabed and equipped with a gravity-based foundation. The proposed procedure is applied to several candidate deployment sites located in the Mediterranean Sea; the incidence of the power take-off restraint and the converter operational profile is fully investigated and some recommendations for preliminary design of wave energy converter devices are provided. Current results show that there is wide scope to make the wave energy sector more competitive on the international market, by properly selecting the main design parameters of point absorbers, on the basis of met-ocean conditions at the deployment site.

  11. Tracking an oil slick from multiple natural sources, Coal Oil Point, California

    International Nuclear Information System (INIS)

    Leifer, Ira; Luyendyk, Bruce; Broderick, Kris

    2006-01-01

    Oil slicks on the ocean surface emitted from natural marine hydrocarbon seeps offshore from Coal Oil Point in the Santa Barbara Channel, California were tracked and sampled over a 2-h period. The objectives were to characterize the seep oil and to track its composition over time using a new sampling device, a catamaran drum sampler (CATDRUMS). The sampler was designed and developed at UCSB. Chromatograms showed that oil originating from an informally named, very active seep area, Shane Seep, primarily evolved during the first hour due to mixing with oil originating from a convergence zone slick surrounding Shane Seep. (author)

  12. Tracking an oil slick from multiple natural sources, Coal Oil Point, California

    Energy Technology Data Exchange (ETDEWEB)

    Leifer, Ira [Marine Sciences Institute, University of California, Santa Barbara, CA 93106 (United States); Luyendyk, Bruce [Department of Geological Sciences, University of California, Santa Barbara, CA 93106 (United States); Broderick, Kris [Exxon/Mobil Exploration Company, 13401 N. Freeway, Houston, TX 77060 (United States)

    2006-06-15

    Oil slicks on the ocean surface emitted from natural marine hydrocarbon seeps offshore from Coal Oil Point in the Santa Barbara Channel, California were tracked and sampled over a 2-h period. The objectives were to characterize the seep oil and to track its composition over time using a new sampling device, a catamaran drum sampler (CATDRUMS). The sampler was designed and developed at UCSB. Chromatograms showed that oil originating from an informally named, very active seep area, Shane Seep, primarily evolved during the first hour due to mixing with oil originating from a convergence zone slick surrounding Shane Seep. (author)

  13. A Multi-Point Method Considering the Maximum Power Point Tracking Dynamic Process for Aerodynamic Optimization of Variable-Speed Wind Turbine Blades

    Directory of Open Access Journals (Sweden)

    Zhiqiang Yang

    2016-05-01

    Full Text Available Due to the dynamic process of maximum power point tracking (MPPT caused by turbulence and large rotor inertia, variable-speed wind turbines (VSWTs cannot maintain the optimal tip speed ratio (TSR from cut-in wind speed up to the rated speed. Therefore, in order to increase the total captured wind energy, the existing aerodynamic design for VSWT blades, which only focuses on performance improvement at a single TSR, needs to be improved to a multi-point design. In this paper, based on a closed-loop system of VSWTs, including turbulent wind, rotor, drive train and MPPT controller, the distribution of operational TSR and its description based on inflow wind energy are investigated. Moreover, a multi-point method considering the MPPT dynamic process for the aerodynamic optimization of VSWT blades is proposed. In the proposed method, the distribution of operational TSR is obtained through a dynamic simulation of the closed-loop system under a specific turbulent wind, and accordingly the multiple design TSRs and the corresponding weighting coefficients in the objective function are determined. Finally, using the blade of a National Renewable Energy Laboratory (NREL 1.5 MW wind turbine as the baseline, the proposed method is compared with the conventional single-point optimization method using the commercial software Bladed. Simulation results verify the effectiveness of the proposed method.

  14. Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands.

    Science.gov (United States)

    Sancineto, Luca; Iraci, Nunzio; Barreca, Maria Letizia; Massari, Serena; Manfroni, Giuseppe; Corazza, Gianmarco; Cecchetti, Violetta; Marcello, Alessandro; Daelemans, Dirk; Pannecouque, Christophe; Tabarrini, Oriana

    2014-09-01

    It is getting clearer that many drugs effective in different therapeutic areas act on multiple rather than single targets. The application of polypharmacology concepts might have numerous advantages especially for disease such as HIV/AIDS, where the rapid emergence of resistance requires a complex combination of more than one drug. In this paper, we have designed three hybrid molecules combining WM5, a quinolone derivative we previously identified as HIV Tat-mediated transcription (TMT) inhibitor, with the tricyclic core of nevirapine and BILR 355BS (BILR) non-nucleoside reverse transcriptase inhibitors (NNRTIs) to investigate whether it could be possible to obtain molecules acting on both transcription steps of the HIV replicative cycle. One among the three designed multiple ligands, reached this goal. Indeed, compound 1 inhibited both TMT and reverse transcriptase (RT) activity. Unexpectedly, while the anti-TMT activity exerted by compound 1 resulted into a selective inhibition of HIV-1 reactivation from latently infected OM10.1 cells, the anti-RT properties shown by all of the synthesized compounds did not translate into an anti-HIV activity in acutely infected cells. Thus, we have herein produced the proof of concept that the design of dual TMT-RT inhibitors is indeed possible, but optimization efforts are needed to obtain more potent derivatives. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Localization of Point Sources for Poisson Equation using State Observers

    KAUST Repository

    Majeed, Muhammad Usman

    2016-08-09

    A method based On iterative observer design is presented to solve point source localization problem for Poisson equation with riven boundary data. The procedure involves solution of multiple boundary estimation sub problems using the available Dirichlet and Neumann data from different parts of the boundary. A weighted sum of these solution profiles of sub-problems localizes point sources inside the domain. Method to compute these weights is also provided. Numerical results are presented using finite differences in a rectangular domain. (C) 2016, IFAC (International Federation of Automatic Control) Hosting by Elsevier Ltd. All rights reserved.

  16. Localization of Point Sources for Poisson Equation using State Observers

    KAUST Repository

    Majeed, Muhammad Usman; Laleg-Kirati, Taous-Meriem

    2016-01-01

    A method based On iterative observer design is presented to solve point source localization problem for Poisson equation with riven boundary data. The procedure involves solution of multiple boundary estimation sub problems using the available Dirichlet and Neumann data from different parts of the boundary. A weighted sum of these solution profiles of sub-problems localizes point sources inside the domain. Method to compute these weights is also provided. Numerical results are presented using finite differences in a rectangular domain. (C) 2016, IFAC (International Federation of Automatic Control) Hosting by Elsevier Ltd. All rights reserved.

  17. Targeting a heterologous protein to multiple plant organelles via rationally designed 5? mRNA tags

    NARCIS (Netherlands)

    Voges, M.J.; Silver, P.A.; Way, J.C.; Mattozzi, M.D.

    2013-01-01

    Background Plant bioengineers require simple genetic devices for predictable localization of heterologous proteins to multiple subcellular compartments. Results We designed novel hybrid signal sequences for multiple-compartment localization and characterize their function when fused to GFP in

  18. An Improved Quantum-Behaved Particle Swarm Optimization Method for Economic Dispatch Problems with Multiple Fuel Options and Valve-Points Effects

    Directory of Open Access Journals (Sweden)

    Hong-Yun Zhang

    2012-09-01

    Full Text Available Quantum-behaved particle swarm optimization (QPSO is an efficient and powerful population-based optimization technique, which is inspired by the conventional particle swarm optimization (PSO and quantum mechanics theories. In this paper, an improved QPSO named SQPSO is proposed, which combines QPSO with a selective probability operator to solve the economic dispatch (ED problems with valve-point effects and multiple fuel options. To show the performance of the proposed SQPSO, it is tested on five standard benchmark functions and two ED benchmark problems, including a 40-unit ED problem with valve-point effects and a 10-unit ED problem with multiple fuel options. The results are compared with differential evolution (DE, particle swarm optimization (PSO and basic QPSO, as well as a number of other methods reported in the literature in terms of solution quality, convergence speed and robustness. The simulation results confirm that the proposed SQPSO is effective and reliable for both function optimization and ED problems.

  19. Improving Graduate Students' Graphing Skills of Multiple Baseline Designs with Microsoft[R] Excel 2007

    Science.gov (United States)

    Lo, Ya-yu; Starling, A. Leyf Peirce

    2009-01-01

    This study examined the effects of a graphing task analysis using the Microsoft[R] Office Excel 2007 program on the single-subject multiple baseline graphing skills of three university graduate students. Using a multiple probe across participants design, the study demonstrated a functional relationship between the number of correct graphing…

  20. Optimizing the diagnostic power with gastric emptying scintigraphy at multiple time points

    Directory of Open Access Journals (Sweden)

    Gajewski Byron J

    2011-05-01

    Full Text Available Abstract Background Gastric Emptying Scintigraphy (GES at intervals over 4 hours after a standardized radio-labeled meal is commonly regarded as the gold standard for diagnosing gastroparesis. The objectives of this study were: 1 to investigate the best time point and the best combination of multiple time points for diagnosing gastroparesis with repeated GES measures, and 2 to contrast and cross-validate Fisher's Linear Discriminant Analysis (LDA, a rank based Distribution Free (DF approach, and the Classification And Regression Tree (CART model. Methods A total of 320 patients with GES measures at 1, 2, 3, and 4 hour (h after a standard meal using a standardized method were retrospectively collected. Area under the Receiver Operating Characteristic (ROC curve and the rate of false classification through jackknife cross-validation were used for model comparison. Results Due to strong correlation and an abnormality in data distribution, no substantial improvement in diagnostic power was found with the best linear combination by LDA approach even with data transformation. With DF method, the linear combination of 4-h and 3-h increased the Area Under the Curve (AUC and decreased the number of false classifications (0.87; 15.0% over individual time points (0.83, 0.82; 15.6%, 25.3%, for 4-h and 3-h, respectively at a higher sensitivity level (sensitivity = 0.9. The CART model using 4 hourly GES measurements along with patient's age was the most accurate diagnostic tool (AUC = 0.88, false classification = 13.8%. Patients having a 4-h gastric retention value >10% were 5 times more likely to have gastroparesis (179/207 = 86.5% than those with ≤10% (18/113 = 15.9%. Conclusions With a mixed group of patients either referred with suspected gastroparesis or investigated for other reasons, the CART model is more robust than the LDA and DF approaches, capable of accommodating covariate effects and can be generalized for cross institutional applications, but

  1. Multiple-membrane multiple-electrolyte redox flow battery design

    Science.gov (United States)

    Yan, Yushan; Gu, Shuang; Gong, Ke

    2017-05-02

    A redox flow battery is provided. The redox flow battery involves multiple-membrane (at least one cation exchange membrane and at least one anion exchange membrane), multiple-electrolyte (one electrolyte in contact with the negative electrode, one electrolyte in contact with the positive electrode, and at least one electrolyte disposed between the two membranes) as the basic characteristic, such as a double-membrane, triple electrolyte (DMTE) configuration or a triple-membrane, quadruple electrolyte (TMQE) configuration. The cation exchange membrane is used to separate the negative or positive electrolyte and the middle electrolyte, and the anion exchange membrane is used to separate the middle electrolyte and the positive or negative electrolyte.

  2. A Sequential Circuit-Based IP Watermarking Algorithm for Multiple Scan Chains in Design-for-Test

    Directory of Open Access Journals (Sweden)

    C. Wu

    2011-06-01

    Full Text Available In Very Large Scale Integrated Circuits (VLSI design, the existing Design-for-Test(DFT based watermarking techniques usually insert watermark through reordering scan cells, which causes large resource overhead, low security and coverage rate of watermark detection. A novel scheme was proposed to watermark multiple scan chains in DFT for solving the problems. The proposed scheme adopts DFT scan test model of VLSI design, and uses a Linear Feedback Shift Register (LFSR for pseudo random test vector generation. All of the test vectors are shifted in scan input for the construction of multiple scan chains with minimum correlation. Specific registers in multiple scan chains will be changed by the watermark circuit for watermarking the design. The watermark can be effectively detected without interference with normal function of the circuit, even after the chip is packaged. The experimental results on several ISCAS benchmarks show that the proposed scheme has lower resource overhead, probability of coincidence and higher coverage rate of watermark detection by comparing with the existing methods.

  3. A new compact fixed-point blackbody furnace

    International Nuclear Information System (INIS)

    Hiraka, K.; Oikawa, H.; Shimizu, T.; Kadoya, S.; Kobayashi, T.; Yamada, Y.; Ishii, J.

    2013-01-01

    More and more NMIs are realizing their primary scale themselves with fixed-point blackbodies as their reference standard. However, commercially available fixed-point blackbody furnaces of sufficient quality are not always easy to obtain. CHINO Corp. and NMIJ, AIST jointly developed a new compact fixed-point blackbody furnace. The new furnace has such features as 1) improved temperature uniformity when compared to previous products, enabling better plateau quality, 2) adoption of the hybrid fixed-point cell structure with internal insulation to improve robustness and thereby to extend lifetime, 3) easily ejectable and replaceable heater unit and fixed-point cell design, leading to reduced maintenance cost, 4) interchangeability among multiple fixed points from In to Cu points. The replaceable cell feature facilitates long term maintenance of the scale through management of a group of fixed-point cells of the same type. The compact furnace is easily transportable and therefore can also function as a traveling standard for disseminating the radiation temperature scale, and for maintaining the scale at the secondary level and industrial calibration laboratories. It is expected that the furnace will play a key role of the traveling standard in the anticipated APMP supplementary comparison of the radiation thermometry scale

  4. Minimum weight design of composite laminates for multiple loads

    International Nuclear Information System (INIS)

    Krikanov, A.A.; Soni, S.R.

    1995-01-01

    A new design method of constructing optimum weight composite laminates for multiple loads is proposed in this paper. A netting analysis approach is used to develop an optimization procedure. Three ply orientations permit development of optimum laminate design without using stress-strain relations. It is proved that stresses in minimum weight laminate reach allowable values in each ply with given load. The optimum ply thickness is defined at maximum value among tensile and compressive loads. Two examples are given to obtain optimum ply orientations, thicknesses and materials. For comparison purposes, calculations of stresses are done in orthotropic material using classical lamination theory. Based upon these calculations, matrix degrades at 30 to 50% of ultimate load. There is no fiber failure and therefore laminates withstand all applied loads in both examples

  5. From Takeoff to Landing: Looking at the Design Process for the Development of NASA Blast at Thanksgiving Point

    Directory of Open Access Journals (Sweden)

    Stephen Ashton

    2011-01-01

    Full Text Available In this article we discuss the process of design used to develop and design the NASA Blast exhibition at Thanksgiving Point, a museum complex in Lehi, Utah. This was a class project for the Advanced Instructional Design Class at Brigham Young University. In an attempt to create a new discourse (Krippendorff, 2006 for Thanksgiving Point visitors and staff members, the design class used a very fluid design approach by utilizing brainstorming, researching, class member personas, and prototyping to create ideas for the new exhibition. Because of the nature of the experience, the design class developed their own techniques to enhance the process of their design. The result of the design was a compelling narrative that brought all the elements of the exhibition together in a cohesive piece.

  6. A Numerical Study on the Excitation of Guided Waves in Rectangular Plates Using Multiple Point Sources

    Directory of Open Access Journals (Sweden)

    Wenbo Duan

    2017-12-01

    Full Text Available Ultrasonic guided waves are widely used to inspect and monitor the structural integrity of plates and plate-like structures, such as ship hulls and large storage-tank floors. Recently, ultrasonic guided waves have also been used to remove ice and fouling from ship hulls, wind-turbine blades and aeroplane wings. In these applications, the strength of the sound source must be high for scanning a large area, or to break the bond between ice, fouling and plate substrate. More than one transducer may be used to achieve maximum sound power output. However, multiple sources can interact with each other, and form a sound field in the structure with local constructive and destructive regions. Destructive regions are weak regions and shall be avoided. When multiple transducers are used it is important that they are arranged in a particular way so that the desired wave modes can be excited to cover the whole structure. The objective of this paper is to provide a theoretical basis for generating particular wave mode patterns in finite-width rectangular plates whose length is assumed to be infinitely long with respect to its width and thickness. The wave modes have displacements in both width and thickness directions, and are thus different from the classical Lamb-type wave modes. A two-dimensional semi-analytical finite element (SAFE method was used to study dispersion characteristics and mode shapes in the plate up to ultrasonic frequencies. The modal analysis provided information on the generation of modes suitable for a particular application. The number of point sources and direction of loading for the excitation of a few representative modes was investigated. Based on the SAFE analysis, a standard finite element modelling package, Abaqus, was used to excite the designed modes in a three-dimensional plate. The generated wave patterns in Abaqus were then compared with mode shapes predicted in the SAFE model. Good agreement was observed between the

  7. Systems near a critical point under multiplicative noise and the concept of effective potential

    Science.gov (United States)

    Shapiro, V. E.

    1993-07-01

    This paper presents a general approach to and elucidates the main features of the effective potential, friction, and diffusion exerted by systems near a critical point due to nonlinear influence of noise. The model is that of a general many-dimensional system of coupled nonlinear oscillators of finite damping under frequently alternating influences, multiplicative or additive, and arbitrary form of the power spectrum, provided the time scales of the system's drift due to noise are large compared to the scales of unperturbed relaxation behavior. The conventional statistical approach and the widespread deterministic effective potential concept use the assumptions about a small parameter which are particular cases of the considered. We show close correspondence between the asymptotic methods of these approaches and base the analysis on this. The results include an analytical treatment of the system's long-time behavior as a function of the noise covering all the range of its table- and bell-shaped spectra, from the monochromatic limit to white noise. The trend is considered both in the coordinate momentum and in the coordinate system's space. Particular attention is paid to the stabilization behavior forced by multiplicative noise. An intermittency, in a broad area of the control parameter space, is shown to be an intrinsic feature of these phenomena.

  8. Designs of Optoelectronic Trinary Signed-Digit Multiplication by use of Joint Spatial Encodings and Optical Correlation

    Science.gov (United States)

    Cherri, Abdallah K.

    1999-02-01

    Trinary signed-digit (TSD) symbolic-substitution-based (SS-based) optical adders, which were recently proposed, are used as the basic modules for designing highly parallel optical multiplications by use of cascaded optical correlators. The proposed multiplications perform carry-free generation of the multiplication partial products of two words in constant time. Also, three different multiplication designs are presented, and new joint spatial encodings for the TSD numbers are introduced. The proposed joint spatial encodings allow one to reduce the SS computation rules involved in optical multiplication. In addition, the proposed joint spatial encodings increase the space bandwidth product of the spatial light modulators of the optical system. This increase is achieved by reduction of the numbers of pixels in the joint spatial encodings for the input TSD operands as well as reduction of the number of pixels used in the proposed matched spatial filters for the optical multipliers.

  9. A Methodology for the Design of Robotic Hands with Multiple Fingers

    Directory of Open Access Journals (Sweden)

    Jorge Eduardo Parada Puig

    2008-11-01

    Full Text Available This paper presents a methodology that has been applied for a design process of anthropomorphic hands with multiple fingers. Biomechanical characteristics of human hand have been analysed so that ergonomic and anthropometric aspects have been used as fundamental references for obtaining grasping mechanisms. A kinematic analysis has been proposed to define the requirements for designing grasping functions. Selection of materials and actuators has been discussed too. This topic has been based on previous experiences with prototypes that have been developed at the Laboratory of Robotics and Mechatronics (LARM of the University of Cassino. An example of the application of the proposed method has been presented for the design of a first prototype of LARM Hand.

  10. The multiplicity of the digital textbook as design object

    DEFF Research Database (Denmark)

    Riis Ebbesen, Toke

    2015-01-01

    Building on a preliminary case study of the Danish educational publisher Systime A/S and its flagship product, the web-based ‘iBog’/‘iBook’, this article explores how digital textbooks can be understood as design. The shaping of digital books is seen as being intertwined in a wider circuit...... reorganization of the publishing company, web-based user interfaces, and ultimately the branding, which market these new digital objects, are building power- ful discourses around the product. Thus it is suggested that the design process of the iBog case can be understood in a model of database-based publishing...... with multiple levels. In the final analysis, the iBog is much more than a product and a technology. It is a brand that goes beyond what can be studied by looking at the digital textbook as a singular artefact....

  11. Supporting Affect Regulation in Children With Multiple Disabilities During Psychotherapy: A Multiple Case Design Study of Therapeutic Attachment. [Miscellaneous Article

    NARCIS (Netherlands)

    Schuengel, C; Sterkenburg, P S; Jeczynski, P; Janssen, C G C; Jongbloed, G

    2009-01-01

    : In a controlled multiple case design study, the development of a therapeutic relationship and its role in affect regulation were studied in 6 children with visual disabilities, severe intellectual disabilities, severe challenging behavior, and prolonged social deprivation. In the 1st phase,

  12. Phase-equilibria for design of coal-gasification processes: dew points of hot gases containing condensible tars. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Prausnitz, J.M.

    1980-05-01

    This research is concerned with the fundamental physical chemistry and thermodynamics of condensation of tars (dew points) from the vapor phase at advanced temperatures and pressures. Fundamental quantitative understanding of dew points is important for rational design of heat exchangers to recover sensible heat from hot, tar-containing gases that are produced in coal gasification. This report includes essentially six contributions toward establishing the desired understanding: (1) Characterization of Coal Tars for Dew-Point Calculations; (2) Fugacity Coefficients for Dew-Point Calculations in Coal-Gasification Process Design; (3) Vapor Pressures of High-Molecular-Weight Hydrocarbons; (4) Estimation of Vapor Pressures of High-Boiling Fractions in Liquefied Fossil Fuels Containing Heteroatoms Nitrogen or Sulfur; and (5) Vapor Pressures of Heavy Liquid Hydrocarbons by a Group-Contribution Method.

  13. Point DCT VLSI Architecture for Emerging HEVC Standard

    Directory of Open Access Journals (Sweden)

    Ashfaq Ahmed

    2012-01-01

    Full Text Available This work presents a flexible VLSI architecture to compute the -point DCT. Since HEVC supports different block sizes for the computation of the DCT, that is, 4×4 up to 32×32, the design of a flexible architecture to support them helps reducing the area overhead of hardware implementations. The hardware proposed in this work is partially folded to save area and to get speed for large video sequences sizes. The proposed architecture relies on the decomposition of the DCT matrices into sparse submatrices in order to reduce the multiplications. Finally, multiplications are completely eliminated using the lifting scheme. The proposed architecture sustains real-time processing of 1080P HD video codec running at 150 MHz.

  14. Aerodynamic and Performance Behavior of a Three-Stage High Efficiency Turbine at Design and Off-Design Operating Points

    Directory of Open Access Journals (Sweden)

    M. T. Schobeiri

    2004-01-01

    Full Text Available This article deals with the aerodynamic and performance behavior of a three-stage high pressure research turbine with 3-D curved blades at its design and off-design operating points. The research turbine configuration incorporates six rows beginning with a stator row. Interstage aerodynamic measurements were performed at three stations, namely downstream of the first rotor row, the second stator row, and the second rotor row. Interstage radial and circumferential traversing presented a detailed flow picture of the middle stage. Performance measurements were carried out within a rotational speed range of 75% to 116% of the design speed. The experimental investigations have been carried out on the recently established multi-stage turbine research facility at the Turbomachinery Performance and Flow Research Laboratory, TPFL, of Texas A&M University.

  15. LDPC decoder with a limited-precision FPGA-based floating-point multiplication coprocessor

    Science.gov (United States)

    Moberly, Raymond; O'Sullivan, Michael; Waheed, Khurram

    2007-09-01

    Implementing the sum-product algorithm, in an FPGA with an embedded processor, invites us to consider a tradeoff between computational precision and computational speed. The algorithm, known outside of the signal processing community as Pearl's belief propagation, is used for iterative soft-decision decoding of LDPC codes. We determined the feasibility of a coprocessor that will perform product computations. Our FPGA-based coprocessor (design) performs computer algebra with significantly less precision than the standard (e.g. integer, floating-point) operations of general purpose processors. Using synthesis, targeting a 3,168 LUT Xilinx FPGA, we show that key components of a decoder are feasible and that the full single-precision decoder could be constructed using a larger part. Soft-decision decoding by the iterative belief propagation algorithm is impacted both positively and negatively by a reduction in the precision of the computation. Reducing precision reduces the coding gain, but the limited-precision computation can operate faster. A proposed solution offers custom logic to perform computations with less precision, yet uses the floating-point format to interface with the software. Simulation results show the achievable coding gain. Synthesis results help theorize the the full capacity and performance of an FPGA-based coprocessor.

  16. Integrated conservation planning for coral reefs: Designing conservation zones for multiple conservation objectives in spatial prioritisation

    Directory of Open Access Journals (Sweden)

    Rafael A. Magris

    2017-07-01

    Full Text Available Decision-makers focus on representing biodiversity pattern, maintaining connectivity, and strengthening resilience to global warming when designing marine protected area (MPA systems, especially in coral reef ecosystems. The achievement of these broad conservation objectives will likely require large areas, and stretch limited funds for MPA implementation. We undertook a spatial prioritisation of Brazilian coral reefs that considered two types of conservation zones (i.e. no-take and multiple use areas and integrated multiple conservation objectives into MPA planning, while assessing the potential impact of different sets of objectives on implementation costs. We devised objectives for biodiversity, connectivity, and resilience to global warming, determined the extent to which existing MPAs achieved them, and designed complementary zoning to achieve all objectives combined in expanded MPA systems. In doing so, we explored interactions between different sets of objectives, determined whether refinements to the existing spatial arrangement of MPAs were necessary, and tested the utility of existing MPAs by comparing their cost effectiveness with an MPA system designed from scratch. We found that MPAs in Brazil protect some aspects of coral reef biodiversity pattern (e.g. threatened fauna and ecosystem types more effectively than connectivity or resilience to global warming. Expanding the existing MPA system was as cost-effective as designing one from scratch only when multiple objectives were considered and management costs were accounted for. Our approach provides a comprehensive assessment of the benefits of integrating multiple objectives in the initial stages of conservation planning, and yields insights for planners of MPAs tackling multiple objectives in other regions.

  17. Design and evaluation of aircraft heat source systems for use with high-freezing point fuels

    Science.gov (United States)

    Pasion, A. J.

    1979-01-01

    The objectives were the design, performance and economic analyses of practical aircraft fuel heating systems that would permit the use of high freezing-point fuels on long-range aircraft. Two hypothetical hydrocarbon fuels with freezing points of -29 C and -18 C were used to represent the variation from current day jet fuels. A Boeing 747-200 with JT9D-7/7A engines was used as the baseline aircraft. A 9300 Km mission was used as the mission length from which the heat requirements to maintain the fuel above its freezing point was based.

  18. Dynamics and mission design near libration points

    CERN Document Server

    Gómez, G; Llibre, J; Martínez, R

    2001-01-01

    It is well known that the restricted three-body problem has triangular equilibrium points. These points are linearly stable for values of the mass parameter, µ , below Routh's critical value, µ 1 . It is also known that in the spatial case they are nonlinearly stable, not for all the initial conditions in a neighborhood of the equilibrium points L 4 , L 5 but for a set of relatively large measures. This follows from the celebrated Kolmogorov-Arnold-Moser theorem. In fact there are neighborhoods of computable size for which one obtains "practical stability" in the sense that the massless partic

  19. Two-point versus multiple-point geostatistics: the ability of geostatistical methods to capture complex geobodies and their facies associations—an application to a channelized carbonate reservoir, southwest Iran

    International Nuclear Information System (INIS)

    Hashemi, Seyyedhossein; Javaherian, Abdolrahim; Ataee-pour, Majid; Khoshdel, Hossein

    2014-01-01

    Facies models try to explain facies architectures which have a primary control on the subsurface heterogeneities and the fluid flow characteristics of a given reservoir. In the process of facies modeling, geostatistical methods are implemented to integrate different sources of data into a consistent model. The facies models should describe facies interactions; the shape and geometry of the geobodies as they occur in reality. Two distinct categories of geostatistical techniques are two-point and multiple-point (geo) statistics (MPS). In this study, both of the aforementioned categories were applied to generate facies models. A sequential indicator simulation (SIS) and a truncated Gaussian simulation (TGS) represented two-point geostatistical methods, and a single normal equation simulation (SNESIM) selected as an MPS simulation representative. The dataset from an extremely channelized carbonate reservoir located in southwest Iran was applied to these algorithms to analyze their performance in reproducing complex curvilinear geobodies. The SNESIM algorithm needs consistent training images (TI) in which all possible facies architectures that are present in the area are included. The TI model was founded on the data acquired from modern occurrences. These analogies delivered vital information about the possible channel geometries and facies classes that are typically present in those similar environments. The MPS results were conditioned to both soft and hard data. Soft facies probabilities were acquired from a neural network workflow. In this workflow, seismic-derived attributes were implemented as the input data. Furthermore, MPS realizations were conditioned to hard data to guarantee the exact positioning and continuity of the channel bodies. A geobody extraction workflow was implemented to extract the most certain parts of the channel bodies from the seismic data. These extracted parts of the channel bodies were applied to the simulation workflow as hard data

  20. Screening of point mutations by multiple SSCP analysis in the dystrophin gene

    Energy Technology Data Exchange (ETDEWEB)

    Lasa, A.; Baiget, M.; Gallano, P. [Hospital Sant Pau, Barcelona (Spain)

    1994-09-01

    Duchenne muscular dystrophy (DMD) is a lethal, X-linked neuromuscular disorder. The population frequency of DMD is one in approximately 3500 boys, of which one third is thought to be a new mutant. The DMD gene is the largest known to date, spanning over 2,3 Mb in band Xp21.2; 79 exons are transcribed into a 14 Kb mRNA coding for a protein of 427 kD which has been named dystrophin. It has been shown that about 65% of affected boys have a gene deletion with a wide variation in localization and size. The remaining affected individuals who have no detectable deletions or duplications would probably carry more subtle mutations that are difficult to detect. These mutations occur in several different exons and seem to be unique to single patients. Their identification represents a formidable goal because of the large size and complexity of the dystrophin gene. SSCP is a very efficient method for the detection of point mutations if the parameters that affect the separation of the strands are optimized for a particular DNA fragment. The multiple SSCP allows the simultaneous study of several exons, and implies the use of different conditions because no single set of conditions will be optimal for all fragments. Seventy-eight DMD patients with no deletion or duplication in the dystrophin gene were selected for the multiple SSCP analysis. Genomic DNA from these patients was amplified using the primers described for the diagnosis procedure (muscle promoter and exons 3, 8, 12, 16, 17, 19, 32, 45, 48 and 51). We have observed different mobility shifts in bands corresponding to exons 8, 12, 43 and 51. In exons 17 and 45, altered electrophoretic patterns were found in different samples identifying polymorphisms already described.

  1. Design of point-of-care (POC) microfluidic medical diagnostic devices

    Science.gov (United States)

    Leary, James F.

    2018-02-01

    Design of inexpensive and portable hand-held microfluidic flow/image cytometry devices for initial medical diagnostics at the point of initial patient contact by emergency medical personnel in the field requires careful design in terms of power/weight requirements to allow for realistic portability as a hand-held, point-of-care medical diagnostics device. True portability also requires small micro-pumps for high-throughput capability. Weight/power requirements dictate use of super-bright LEDs and very small silicon photodiodes or nanophotonic sensors that can be powered by batteries. Signal-to-noise characteristics can be greatly improved by appropriately pulsing the LED excitation sources and sampling and subtracting noise in between excitation pulses. The requirements for basic computing, imaging, GPS and basic telecommunications can be simultaneously met by use of smartphone technologies, which become part of the overall device. Software for a user-interface system, limited real-time computing, real-time imaging, and offline data analysis can be accomplished through multi-platform software development systems that are well-suited to a variety of currently available cellphone technologies which already contain all of these capabilities. Microfluidic cytometry requires judicious use of small sample volumes and appropriate statistical sampling by microfluidic cytometry or imaging for adequate statistical significance to permit real-time (typically medical decisions for patients at the physician's office or real-time decision making in the field. One or two drops of blood obtained by pin-prick should be able to provide statistically meaningful results for use in making real-time medical decisions without the need for blood fractionation, which is not realistic in the field.

  2. Design and use of multiple blade slurry sawing in a production atmosphere

    Science.gov (United States)

    Lynah, F. P., Jr.; Ross, J. B.

    1982-01-01

    The technique and uses of the multiple blade slurry (MBS) saw are considered. Multiple bands of steel are arranged in a frame and the frame is reciprocated with the steel bands to a workpiece, while simultaneously applying abrasive at the point of contact. The blades wear slots in the workpiece and progress through the piece resulting in several parts of wafers. The transition to MBA from diamond slicing is justified by savings resulting from minimized kerf losses, minimized subsurface damage, and improved surface quality off the saw. This allows wafering much closer to finished thickness specifications. The current state of the art MBS technology must be significantly improved if the low cost solar array (LSA) goals are to be attained. It is concluded that although MBS will never be the answer to every wafering requirement, the economical production of wafers to LSA project specifications will be achieved.

  3. Teach Graphic Design Basics with PowerPoint

    Science.gov (United States)

    Lazaros, Edward J.; Spotts, Thomas H.

    2007-01-01

    While PowerPoint is generally regarded as simply software for creating slide presentations, it includes often overlooked--but powerful--drawing tools. Because it is part of the Microsoft Office package, PowerPoint comes preloaded on many computers and thus is already available in many classrooms. Since most computers are not preloaded with good…

  4. Does decision documentation help junior designers rationalize their decisions? A comparative multiple-case study

    OpenAIRE

    Heesch, U. van; Avgeriou, P.; Tang, A.

    2013-01-01

    Software architecture design is challenging, especially for junior software designers. Lacking practice and experience, junior designers need process support in order to make rational architecture decisions. In this paper, we present the results of a comparative multiple-case study conducted to find out if decision viewpoints from van Heesch et al. (2012, in press) can provide such a support. The case study was conducted with four teams of software engineering students working in industrial s...

  5. Generation of synthetic time histories compatible with multiple-damping design response spectra

    International Nuclear Information System (INIS)

    Lilhanand, K.; Tseng, W.S.

    1987-01-01

    Seismic design of nuclear power plants as currently practiced requires time history analyses be performed to generate floor response spectra for seismic qualification of piping, equipment, and components. Since design response spectra are normally prescribed in the form of smooth spectra, the generation of synthetic time histories whose response spectra closely match the ''target'' design spectra of multiple damping values, is often required for the seismic time history analysis purpose. Various methods of generation of synthetic time histories compatible with target response spectra have been proposed in the literature. Since the mathematical problem of determining a time history from a given set of response spectral values is not unique, an exact solution is not possible, and all the proposed methods resort to some forms of approximate solutions. In this paper, a new iteration scheme, is described which effectively removes the difficulties encountered by the existing methods. This new iteration scheme can not only improve the accuracy of spectrum matching for a single-damping target spectrum, but also automate the spectrum matching for multiple-damping target spectra. The applicability and limitations as well as the method adopted to improve the numerical stability of this new iteration scheme are presented. The effectiveness of this new iteration scheme is illustrated by two example applications

  6. Design and Evaluation of Large-Aperture Gallium Fixed-Point Blackbody

    Science.gov (United States)

    Khromchenko, V. B.; Mekhontsev, S. N.; Hanssen, L. M.

    2009-02-01

    To complement existing water bath blackbodies that now serve as NIST primary standard sources in the temperature range from 15 °C to 75 °C, a gallium fixed-point blackbody has been recently built. The main objectives of the project included creating an extended-area radiation source with a target emissivity of 0.9999 capable of operating either inside a cryo-vacuum chamber or in a standard laboratory environment. A minimum aperture diameter of 45 mm is necessary for the calibration of radiometers with a collimated input geometry or large spot size. This article describes the design and performance evaluation of the gallium fixed-point blackbody, including the calculation and measurements of directional effective emissivity, estimates of uncertainty due to the temperature drop across the interface between the pure metal and radiating surfaces, as well as the radiometrically obtained spatial uniformity of the radiance temperature and the melting plateau stability. Another important test is the measurement of the cavity reflectance, which was achieved by using total integrated scatter measurements at a laser wavelength of 10.6 μm. The result allows one to predict the performance under the low-background conditions of a cryo-chamber. Finally, results of the spectral radiance comparison with the NIST water-bath blackbody are provided. The experimental results are in good agreement with predicted values and demonstrate the potential of our approach. It is anticipated that, after completion of the characterization, a similar source operating at the water triple point will be constructed.

  7. Design of multiple representations e-learning resources based on a contextual approach for the basic physics course

    Science.gov (United States)

    Bakri, F.; Muliyati, D.

    2018-05-01

    This research aims to design e-learning resources with multiple representations based on a contextual approach for the Basic Physics Course. The research uses the research and development methods accordance Dick & Carey strategy. The development carried out in the digital laboratory of Physics Education Department, Mathematics and Science Faculty, Universitas Negeri Jakarta. The result of the process of product development with Dick & Carey strategy, have produced e-learning design of the Basic Physics Course is presented in multiple representations in contextual learning syntax. The appropriate of representation used in the design of learning basic physics include: concept map, video, figures, data tables of experiment results, charts of data tables, the verbal explanations, mathematical equations, problem and solutions example, and exercise. Multiple representations are presented in the form of contextual learning by stages: relating, experiencing, applying, transferring, and cooperating.

  8. Development of a Multi-Point Microwave Interferometry (MPMI) Method

    Energy Technology Data Exchange (ETDEWEB)

    Specht, Paul Elliott [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Cooper, Marcia A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jilek, Brook Anton [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    A multi-point microwave interferometer (MPMI) concept was developed for non-invasively tracking a shock, reaction, or detonation front in energetic media. Initially, a single-point, heterodyne microwave interferometry capability was established. The design, construction, and verification of the single-point interferometer provided a knowledge base for the creation of the MPMI concept. The MPMI concept uses an electro-optic (EO) crystal to impart a time-varying phase lag onto a laser at the microwave frequency. Polarization optics converts this phase lag into an amplitude modulation, which is analyzed in a heterodyne interfer- ometer to detect Doppler shifts in the microwave frequency. A version of the MPMI was constructed to experimentally measure the frequency of a microwave source through the EO modulation of a laser. The successful extraction of the microwave frequency proved the underlying physical concept of the MPMI design, and highlighted the challenges associated with the longer microwave wavelength. The frequency measurements made with the current equipment contained too much uncertainty for an accurate velocity measurement. Potential alterations to the current construction are presented to improve the quality of the measured signal and enable multiple accurate velocity measurements.

  9. Accelerating simulation for the multiple-point statistics algorithm using vector quantization

    Science.gov (United States)

    Zuo, Chen; Pan, Zhibin; Liang, Hao

    2018-03-01

    Multiple-point statistics (MPS) is a prominent algorithm to simulate categorical variables based on a sequential simulation procedure. Assuming training images (TIs) as prior conceptual models, MPS extracts patterns from TIs using a template and records their occurrences in a database. However, complex patterns increase the size of the database and require considerable time to retrieve the desired elements. In order to speed up simulation and improve simulation quality over state-of-the-art MPS methods, we propose an accelerating simulation for MPS using vector quantization (VQ), called VQ-MPS. First, a variable representation is presented to make categorical variables applicable for vector quantization. Second, we adopt a tree-structured VQ to compress the database so that stationary simulations are realized. Finally, a transformed template and classified VQ are used to address nonstationarity. A two-dimensional (2D) stationary channelized reservoir image is used to validate the proposed VQ-MPS. In comparison with several existing MPS programs, our method exhibits significantly better performance in terms of computational time, pattern reproductions, and spatial uncertainty. Further demonstrations consist of a 2D four facies simulation, two 2D nonstationary channel simulations, and a three-dimensional (3D) rock simulation. The results reveal that our proposed method is also capable of solving multifacies, nonstationarity, and 3D simulations based on 2D TIs.

  10. MULTIPLE ECH LAUNCHER CONTROL SYSTEM

    International Nuclear Information System (INIS)

    GREEN, M.T.; PONCE, D.; GRUNLOH, H.J.; ELLIS, R.A.; GROSNICKLE, W.H.; HUMPHREY, R.L.

    2004-03-01

    OAK-B135 The addition of new, high power gyrotrons to the heating and current drive arsenal at DIII-D, required a system upgrade for control of fully steerable ECH Launchers. Each launcher contains two pointing mirrors with two degrees of mechanical freedom. The two flavors of motion are called facet and tilt. Therefore up to four channels of motion per launcher need to be controlled. The system utilizes absolute encoders to indicate mirror position and therefore direction of the microwave beam. The launcher movement is primarily controlled by PLC, but future iterations of design, may require this control to be accomplished by a CPU on fast bus such as Compact PCI. This will be necessary to accomplish real time position control. Safety of equipment and personnel is of primary importance when controlling a system of moving parts. Therefore multiple interlocks and fault status enunciators have been implemented. This paper addresses the design of a Multiple ECH Launcher Control System, and characterizes the flexibility needed to upgrade to a real time position control system in the future

  11. Design of 6 Mev linear accelerator based pulsed thermal neutron source: FLUKA simulation and experiment

    Energy Technology Data Exchange (ETDEWEB)

    Patil, B.J., E-mail: bjp@physics.unipune.ac.in [Department of Physics, University of Pune, Pune 411 007 (India); Chavan, S.T.; Pethe, S.N.; Krishnan, R. [SAMEER, IIT Powai Campus, Mumbai 400 076 (India); Bhoraskar, V.N. [Department of Physics, University of Pune, Pune 411 007 (India); Dhole, S.D., E-mail: sanjay@physics.unipune.ac.in [Department of Physics, University of Pune, Pune 411 007 (India)

    2012-01-15

    The 6 MeV LINAC based pulsed thermal neutron source has been designed for bulk materials analysis. The design was optimized by varying different parameters of the target and materials for each region using FLUKA code. The optimized design of thermal neutron source gives flux of 3 Multiplication-Sign 10{sup 6}ncm{sup -2}s{sup -1} with more than 80% of thermal neutrons and neutron to gamma ratio was 1 Multiplication-Sign 10{sup 4}ncm{sup -2}mR{sup -1}. The results of prototype experiment and simulation are found to be in good agreement with each other. - Highlights: Black-Right-Pointing-Pointer The optimized 6 eV linear accelerator based thermal neutron source using FLUKA simulation. Black-Right-Pointing-Pointer Beryllium as a photonuclear target and reflector, polyethylene as a filter and shield, graphite as a moderator. Black-Right-Pointing-Pointer Optimized pulsed thermal neutron source gives neutron flux of 3 Multiplication-Sign 10{sup 6} n cm{sup -2} s{sup -1}. Black-Right-Pointing-Pointer Results of the prototype experiment were compared with simulations and are found to be in good agreement. Black-Right-Pointing-Pointer This source can effectively be used for the study of bulk material analysis and activation products.

  12. Designed multiple ligands in metabolic disease research: from concept to platform.

    Science.gov (United States)

    Gattrell, W; Johnstone, C; Patel, S; Smith, C Sambrook; Scheel, A; Schindler, M

    2013-08-01

    Type 2 diabetes mellitus (T2DM) is a multifactorial disease, and drug monotherapy typically results in unsatisfactory treatment outcomes for patients. Even when used in combination, existing therapies lack efficacy in the long term. Designed multiple ligands (DMLs) are compounds developed to modulate multiple targets relevant to a disease. DMLs offer the potential to yield greater efficacy over monotherapies, either by modulating different biological pathways, or by boosting a single one. However, examples of DMLs progressing into clinical trials, or onto the market are rare; DML drug discovery is challenging, and perceived by some to be almost impossible. Nevertheless, with the judicious selection of biological targets, both from a biological and chemical perspective, it is possible to develop drug-like DMLs. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. [Concern points and considerations for pharmacodynamic study design of new traditional Chinese medicines].

    Science.gov (United States)

    Huang, Fang-Hua

    2014-03-01

    Pharmacodynamic (PD) studies play an important role in research and development of new traditonal Chinese medicines (TCMs). Phamacologic and toxicologic studies that aim to research drug ability can provide supporting data for the clinical trials and reduce the risk of clinical trials. In recent years, PD studies in TCMs are developing and progressing, but there are still some problems affecting the value of PD studies in the development of new TCMs. The value of PD studies depends on scientific and rational study design. This article summaries some defects in PD study design of new TCMs that are common in the application data, including defects in study type, testing targets, dosing, duration of administration, control group, testing time. This article also discusses some points of concern and specific requirements for PD study design of new TCMs.

  14. Modelling a real-world buried valley system with vertical non-stationarity using multiple-point statistics

    DEFF Research Database (Denmark)

    He, Xiulan; Sonnenborg, Torben; Jørgensen, Flemming

    2017-01-01

    -stationary geological system characterized by a network of connected buried valleys that incise deeply into layered Miocene sediments (case study in Denmark). The results show that, based on fragmented information of the formation boundaries, the MPS partition method is able to simulate a non-stationary system......Stationarity has traditionally been a requirement of geostatistical simulations. A common way to deal with non-stationarity is to divide the system into stationary sub-regions and subsequently merge the realizations for each region. Recently, the so-called partition approach that has...... the flexibility to model non-stationary systems directly was developed for multiple-point statistics simulation (MPS). The objective of this study is to apply the MPS partition method with conventional borehole logs and high-resolution airborne electromagnetic (AEM) data, for simulation of a real-world non...

  15. Design of Neutral-Point Voltage Controller of a Three-level NPC Inverter with Small DC-Link Capacitors

    DEFF Research Database (Denmark)

    Maheshwari, Ram Krishan; Munk-Nielsen, Stig; Busquets-Monge, S.

    2013-01-01

    A Neutral-Point-Clamped (NPC) three-level inverter with small dc-link capacitors is presented in this paper. The inverter requires zero average neutral-point current for stable neutral-point voltage. The small dc-link capacitors may not maintain capacitor voltage balance, even with zero neutral......-point voltage control on the basis of the continuous model. The design method for optimum performance is discussed. The implementation of the proposed modulation strategy and the controller is very simple. The controller is implemented in a 7.5 kW induction machine based drive with only 14 ìF dc-link capacitors...

  16. Point specificity in acupuncture

    Directory of Open Access Journals (Sweden)

    Choi Emma M

    2012-02-01

    Full Text Available Abstract The existence of point specificity in acupuncture is controversial, because many acupuncture studies using this principle to select control points have found that sham acupoints have similar effects to those of verum acupoints. Furthermore, the results of pain-related studies based on visual analogue scales have not supported the concept of point specificity. In contrast, hemodynamic, functional magnetic resonance imaging and neurophysiological studies evaluating the responses to stimulation of multiple points on the body surface have shown that point-specific actions are present. This review article focuses on clinical and laboratory studies supporting the existence of point specificity in acupuncture and also addresses studies that do not support this concept. Further research is needed to elucidate the point-specific actions of acupuncture.

  17. Mixed-flow vertical tubular hydraulic turbine. Determination of proper design duty point

    Energy Technology Data Exchange (ETDEWEB)

    Sirok, B. [Ljubljana Univ. (Slovenia). Faculty of Mechanical Engineering; Bergant, A. [Litostroj Power, d.o.o., Ljubljana (Slovenia); Hoefler, E.

    2011-12-15

    A new vertical single-regulated mixed-flow turbine with conical guide apparatus and without spiral casing is presented in this paper. Runner blades are fixed to the hub and runner band and resemble to the Francis type runner of extremely high specific speed. Due to lack of information and guidelines for the design of a new turbine, a theoretical model was developed in order to determinate the design duty point, i.e. to determine the optimum narrow operation range of the turbine. It is not necessary to know the kinematic conditions at the runner inlet, but only general information on the geometry of turbine flow-passage, meridional contour of the runner and blading, the number of blades and the turbine speed of rotation. The model is based on the integral tangential lift coefficient, which is the average value over the entire runner blading. The results are calculated for the lift coefficient 0.5 and 0.6, for the flow coefficient range from 0.2 to 0.36, for the number of the blades between 5 and 13, and are finally presented in the Cordier diagram (specific speed vs. specific diameter). Calculated results of the turbine optimum operation in Cordier diagram correspond very well to the adequate area of Kaplan turbines with medium and low specific speed and extends into the area of Francis turbines with high specific speed. Presented model clearly highlights the parameters that affect specific load of the runner blade row and therefore the optimum turbine operation (discharge - turbine head). The presented method is not limited to a specific reaction type of the hydraulic turbine. The method can therefore be applied to a wide range from mixed-flow (radial-axial) turbines to the axial turbines. Applicability of the method may be considered as a tool in the first stage of the turbine design i.e. when designing the meridional geometry and selecting the number of blades according to calculated operating point. Geometric and energy parameters are generally defined to an

  18. Pressure Points in Reading Comprehension: A Quantile Multiple Regression Analysis

    Science.gov (United States)

    Logan, Jessica

    2017-01-01

    The goal of this study was to examine how selected pressure points or areas of vulnerability are related to individual differences in reading comprehension and whether the importance of these pressure points varies as a function of the level of children's reading comprehension. A sample of 245 third-grade children were given an assessment battery…

  19. Residue-based Coordinated Selection and Parameter Design of Multiple Power System Stabilizers (PSSs)

    DEFF Research Database (Denmark)

    Su, Chi; Hu, Weihao; Fang, Jiakun

    2013-01-01

    data from time domain simulations. Then a coordinated approach for multiple PSS selection and parameter design based on residue method is proposed and realized in MATLAB m-files. Particle swarm optimization (PSO) is adopted in the coordination process. The IEEE 39-bus New England system model...

  20. Digital dashboard design using multiple data streams for disease surveillance with influenza surveillance as an example.

    Science.gov (United States)

    Cheng, Calvin K Y; Ip, Dennis K M; Cowling, Benjamin J; Ho, Lai Ming; Leung, Gabriel M; Lau, Eric H Y

    2011-10-14

    Great strides have been made exploring and exploiting new and different sources of disease surveillance data and developing robust statistical methods for analyzing the collected data. However, there has been less research in the area of dissemination. Proper dissemination of surveillance data can facilitate the end user's taking of appropriate actions, thus maximizing the utility of effort taken from upstream of the surveillance-to-action loop. The aims of the study were to develop a generic framework for a digital dashboard incorporating features of efficient dashboard design and to demonstrate this framework by specific application to influenza surveillance in Hong Kong. Based on the merits of the national websites and principles of efficient dashboard design, we designed an automated influenza surveillance digital dashboard as a demonstration of efficient dissemination of surveillance data. We developed the system to synthesize and display multiple sources of influenza surveillance data streams in the dashboard. Different algorithms can be implemented in the dashboard for incorporating all surveillance data streams to describe the overall influenza activity. We designed and implemented an influenza surveillance dashboard that utilized self-explanatory figures to display multiple surveillance data streams in panels. Indicators for individual data streams as well as for overall influenza activity were summarized in the main page, which can be read at a glance. Data retrieval function was also incorporated to allow data sharing in standard format. The influenza surveillance dashboard serves as a template to illustrate the efficient synthesization and dissemination of multiple-source surveillance data, which may also be applied to other diseases. Surveillance data from multiple sources can be disseminated efficiently using a dashboard design that facilitates the translation of surveillance information to public health actions.

  1. Cleaning Massive Sonar Point Clouds

    DEFF Research Database (Denmark)

    Arge, Lars Allan; Larsen, Kasper Green; Mølhave, Thomas

    2010-01-01

    We consider the problem of automatically cleaning massive sonar data point clouds, that is, the problem of automatically removing noisy points that for example appear as a result of scans of (shoals of) fish, multiple reflections, scanner self-reflections, refraction in gas bubbles, and so on. We...

  2. Multiple-Robot Systems for USAR: Key Design Attributes and Deployment Issues

    Directory of Open Access Journals (Sweden)

    Choon Yue Wong

    2011-03-01

    Full Text Available The interaction between humans and robots is undergoing an evolution. Progress in this evolution means that humans are close to robustly deploying multiple robots. Urban search and rescue (USAR can benefit greatly from such capability. The review shows that with state of the art artificial intelligence, robots can work autonomously but still require human supervision. It also shows that multiple robot deployment (MRD is more economical, shortens mission durations, adds reliability as well as addresses missions impossible with one robot and payload constraints. By combining robot autonomy and human supervision, the benefits of MRD can be applied to USAR while at the same time minimizing human exposure to danger. This is achieved with a single-human multiple-robot system (SHMRS. However, designers of the SHMRS must consider key attributes such as the size, composition and organizational structure of the robot collective. Variations in these attributes also induce fluctuations in issues within SHMRS deployment such as robot communication and computational load as well as human cognitive workload and situation awareness (SA. Research is essential to determine how the attributes can be manipulated to mitigate these issues while meeting the requirements of the USAR mission.

  3. Multiple-Robot Systems for USAR: Key Design Attributes and Deployment Issues

    Directory of Open Access Journals (Sweden)

    Choon Yue Wong

    2011-03-01

    Full Text Available The interaction between humans and robots is undergoing an evolution. Progress in this evolution means that humans are close to robustly deploying multiple robots. Urban search and rescue (USAR can benefit greatly from such capability. The review shows that with state of the art artificial intelligence, robots can work autonomously but still require human supervision. It also shows that multiple robot deployment (MRD is more economical, shortens mission durations, adds reliability as well as addresses missions impossible with one robot and payload constraints. By combining robot autonomy and human supervision, the benefits of MRD can be applied to USAR while at the same time minimizing human exposure to danger. This is achieved with a single-human multiple-robot system (SHMRS. However, designers of the SHMRS must consider key attributes such as the size, composition and organizational structure of the robot collective. Variations in these attributes also induce fluctuations in issues within SHMRS deployment such as robot communication and computational load as well as human cognitive workload and situation awareness (SA.Research is essential to determine how the attributes can be manipulated to mitigate these issues while meeting the requirements of the USAR mission.

  4. Point design for deuterium-deuterium compact reversed-field pinch reactors

    International Nuclear Information System (INIS)

    Dabiri, A.E.; Dobrott, D.R.; Gurol, H.; Schnack, D.D.

    1984-01-01

    A deuterium-deuterium (D-D) reversed-field pinch (RFP) reactor may be made comparable in size and cost to a deuterium-tritium (D-T) reactor at the expense of high-thermal heat load to the first wall. This heat load is the result of the larger percentage of fusion power in charged particles in the D-D reaction as compared to the D-T reaction. The heat load may be reduced by increasing the reactor size and hence the cost. In addition to this ''degraded'' design, the size may be kept small by means of a higher heat load wall, or by means of a toroidal divertor, in which case most of the heat load seen by the wall is in the form of radiation. Point designs are developed for these approaches and cost studies are performed and compared with a D-T reactor. The results indicate that the cost of electricity of a D-D RFP reactor is about20% higher than a D-T RFP reactor. This increased cost could be offset by the inherent safety features of the D-D fuel cycle

  5. Investigating lithological and geophysical relationships with applications to geological uncertainty analysis using Multiple-Point Statistical methods

    DEFF Research Database (Denmark)

    Barfod, Adrian

    The PhD thesis presents a new method for analyzing the relationship between resistivity and lithology, as well as a method for quantifying the hydrostratigraphic modeling uncertainty related to Multiple-Point Statistical (MPS) methods. Three-dimensional (3D) geological models are im...... is to improve analysis and research of the resistivity-lithology relationship and ensemble geological/hydrostratigraphic modeling. The groundwater mapping campaign in Denmark, beginning in the 1990’s, has resulted in the collection of large amounts of borehole and geophysical data. The data has been compiled...... in two publicly available databases, the JUPITER and GERDA databases, which contain borehole and geophysical data, respectively. The large amounts of available data provided a unique opportunity for studying the resistivity-lithology relationship. The method for analyzing the resistivity...

  6. The Modular Point Design for Heavy Ion Fusion

    International Nuclear Information System (INIS)

    Yu, S.S.; Barnard, J.J.; Briggs, R.J.; Callahan, D.; Celata, C.M.; Chao, L.; Davidson, R.; Debonnel, C.S.; Eylon, S.; Friedman, A.; Henestroza, E.; Kaganovich, I.; Kwan, J.W.; Lee, E.P.; Leitner, M.; Logan, B.G.; Meier, W.; Peterson, P.F.; Reginato, L.; Rose, D.; Roy, P.; Waldron, W.; Welch, D.R.

    2004-01-01

    We report on an ongoing study on modular Heavy Ion Fusion drivers. The modular driver is characterized by 10 to 20 nearly identical induction linacs, each carrying a single high current beam. In this scheme, the Integrated Research Experiment (IRE) can be one of the full size induction linacs. Hence, this approach offers significant advantages in terms of driver development path. For beam transport, these modules use solenoids which are capable of carrying high line charge densities, even at low energies. A new injector concept allows compression of the beam to high line densities right at the source. The final drift compression is performed in a plasma, in which the large repulsive space charge effects are neutralized. Finally, the beam is transversely compressed onto the target, using either external solenoids or current-carrying channels (in the Assisted Pinch Mode of beam propagation). We will report on progress towards a self-consistent point design from injector to target. Considerations of driver architecture, chamber environment as well as the methodology for meeting target requirements of spot size, pulse shape and symmetry will also be described. Finally, some near-term experiments to address the key scientific issues will be discussed

  7. The Modular Point Design for Heavy Ion Fusion

    International Nuclear Information System (INIS)

    Yu, S.S.; Barnard, J.J.; Briggs, R.J.; Callahan-Miller, D.; Celata, C.M.; Chao, L.; Davidson, R.; Debonnel, C.S.; Eylon, S.; Friedman, A.; Henestroza, E.; Kaganovich, I.; Kwan, J.W.; Lee, E.P.; Leitner, M.; Logan, B.G.; Meier, W.; Peterson, P.F.; Reginato, L.; Rose, D.; Roy, P.; Waldron, W.; Welch, D.R.

    2005-01-01

    We report on an ongoing study on modular Heavy Ion Fusion drivers. The modular driver is characterized by tens (∼ 20) nearly identical induction linacs, each carrying a single high current beam. In this scheme, the Integrated Research Experiment (IRE) can be one of the full size induction linacs. Hence, this approach offers significant advantages in terms of driver development path. For beam transport, these modules use solenoids which are capable of carrying high line charge densities, even at low energies. A new injector concept allows compression of the beam to high line densities right at the source. The final drift compression is performed in a plasma, in which the large repulsive space charge effects are neutralized. Finally, the beam is transversely compressed onto the target, using either external solenoids or current-carrying channels (in the Assisted Pinch Mode of beam propagation). We will report on progress towards a self-consistent point design from injector to target. Considerations of driver architecture, chamber environment as well as the methodology for meeting target requirements of spot size, pulse shape and symmetry will also be described. Finally, some near-term experiments to address the key scientific issues will be discussed

  8. The design of an ultra-thin and multiple channels optical receiving antenna system with freeform lenses

    Science.gov (United States)

    Zhang, Lingyun; Cheng, Dewen; Hu, Yuan; Song, Weitao; Wang, Yongtian

    2014-11-01

    Visible Light Communications (VLC) has become an emerging area of research since it can provide higher data transmission speed and wider bandwidth. The white LEDs are very important components of the VLC system, because it has the advantages of higher brightness, lower power consumption, and a longer lifetime. More importantly, their intensity and color are modulatable. Besides the light source, the optical antenna system also plays a very important role in the VLC system since it determines the optical gain, effective working area and transmission rate of the VLC system. In this paper, we propose to design an ultra-thin and multiple channels optical antenna system by tiling multiple off-axis lenses, each of which consists of two reflective and two refractive freeform surfaces. The tiling of multiple systems and detectors but with different band filters makes it possible to design a wavelength division multiplexing VLC system to highly improve the system capacity. The field of view of the designed antenna system is 30°, the entrance pupil diameter is 1.5mm, and the thickness of the system is under 4mm. The design methods are presented and the results are discussed in the last section of this paper. Besides the optical gain is analyzed and calculated. The antenna system can be tiled up to four channels but without the increase of thickness.

  9. The computer-aided design of a servo system as a multiple-criteria decision problem

    NARCIS (Netherlands)

    Udink ten Cate, A.J.

    1986-01-01

    This paper treats the selection of controller gains of a servo system as a multiple-criteria decision problem. In contrast to the usual optimization-based approaches to computer-aided design, inequality constraints are included in the problem as unconstrained objectives. This considerably simplifies

  10. Spatial judgments in the horizontal and vertical planes from different vantage points.

    Science.gov (United States)

    Prytz, Erik; Scerbo, Mark W

    2012-01-01

    Todorović (2008 Perception 37 106-125) reported that there are systematic errors in the perception of 3-D space when viewing 2-D linear perspective drawings depending on the observer's vantage point. Because these findings were restricted to the horizontal plane, the current study was designed to determine the nature of these errors in the vertical plane. Participants viewed an image containing multiple colonnades aligned on parallel converging lines receding to a vanishing point. They were asked to judge where, in the physical room, the next column should be placed. The results support Todorović in that systematic deviations in the spatial judgments depended on vantage point for both the horizontal and vertical planes. However, there are also marked differences between the two planes. While judgments in both planes failed to compensate adequately for the vantage-point shift, the vertical plane induced greater distortions of the stimulus image itself within each vantage point.

  11. Dynamics and mission design near libration points

    CERN Document Server

    Gómez, G; Jorba, A; Masdemont, J

    2001-01-01

    The aim of this book is to explain, analyze and compute the kinds of motions that appear in an extended vicinity of the geometrically defined equilateral points of the Earth-Moon system, as a source of possible nominal orbits for future space missions. The methodology developed here is not specific to astrodynamics problems. The techniques are developed in such a way that they can be used to study problems that can be modeled by dynamical systems. Contents: Global Stability Zones Around the Triangular Libration Points; The Normal Form Around L 5 in the Three-dimensional RTBP; Normal Form of th

  12. Dynamics and mission design near libration points

    CERN Document Server

    Gómez, G; Simo, C; Martínez, R

    2001-01-01

    In this book the problem of station keeping is studied for orbits near libration points in the solar system. The main focus is on orbits near halo ones in the (Earth+Moon)-Sun system. Taking as starting point the restricted three-body problem, the motion in the full solar system is considered as a perturbation of this simplified model. All the study is done with enough generality to allow easy application to other primary-secondary systems as a simple extension of the analytical and numerical computations. Contents: Bibliographical Survey; Halo Orbits. Analytical and Numerical Study; The Neigh

  13. Microseismic Monitoring Design Optimization Based on Multiple Criteria Decision Analysis

    Science.gov (United States)

    Kovaleva, Y.; Tamimi, N.; Ostadhassan, M.

    2017-12-01

    Borehole microseismic monitoring of hydraulic fracture treatments of unconventional reservoirs is a widely used method in the oil and gas industry. Sometimes, the quality of the acquired microseismic data is poor. One of the reasons for poor data quality is poor survey design. We attempt to provide a comprehensive and thorough workflow, using multiple criteria decision analysis (MCDA), to optimize planning micriseismic monitoring. So far, microseismic monitoring has been used extensively as a powerful tool for determining fracture parameters that affect the influx of formation fluids into the wellbore. The factors that affect the quality of microseismic data and their final results include average distance between microseismic events and receivers, complexity of the recorded wavefield, signal-to-noise ratio, data aperture, etc. These criteria often conflict with each other. In a typical microseismic monitoring, those factors should be considered to choose the best monitoring well(s), optimum number of required geophones, and their depth. We use MDCA to address these design challenges and develop a method that offers an optimized design out of all possible combinations to produce the best data acquisition results. We believe that this will be the first research to include the above-mentioned factors in a 3D model. Such a tool would assist companies and practicing engineers in choosing the best design parameters for future microseismic projects.

  14. Adaptive aspirations and performance heterogeneity : Attention allocation among multiple reference points

    NARCIS (Netherlands)

    Blettner, D.P.; He, Z.; Hu, S.; Bettis, R.

    Organizations learn and adapt their aspiration levels based on reference points (prior aspiration, prior performance, and prior performance of reference groups). The relative attention that organizations allocate to these reference points impacts organizational search and strategic decisions.

  15. Portable Amplifier Design for a Novel EEG Monitor in Point-of-Care Applications.

    Science.gov (United States)

    Luan, Bo; Sun, Mingui; Jia, Wenyan

    2012-01-01

    The Electroencephalography (EEG) is a common diagnostic tool for neurological diseases and dysfunctions, such as epilepsy and insomnia. However, the current EEG technology cannot be utilized quickly and conveniently at the point of care due to the complex skin preparation procedures required and the inconvenient EEG data acquisition systems. This work presents a portable amplifier design that integrates a set of skin screw electrodes and a wireless data link. The battery-operated amplifier contains an instrumentation amplifier, two noninverting amplifiers, two high-pass filters, and a low-pass filter. It is able to magnify the EEG signals over 10,000 times and has a high impedance, low noise, small size and low weight. Our electrode and amplifier are ideal for point-of-care applications, especially during transportation of patients suffering from traumatic brain injury or stroke.

  16. Design of a hybrid command and control mobile botnet

    CSIR Research Space (South Africa)

    Pieterse, H

    2013-05-01

    Full Text Available and control mobile botnet. The hybrid design explores the efficiency of multiple command and control channels against the following objectives: no single point of failure within the topology, low cost for command dissemination, limited network activities...

  17. Design and implementation of the modified signed digit multiplication routine on a ternary optical computer.

    Science.gov (United States)

    Xu, Qun; Wang, Xianchao; Xu, Chao

    2017-06-01

    Multiplication with traditional electronic computers is faced with a low calculating accuracy and a long computation time delay. To overcome these problems, the modified signed digit (MSD) multiplication routine is established based on the MSD system and the carry-free adder. Also, its parallel algorithm and optimization techniques are studied in detail. With the help of a ternary optical computer's characteristics, the structured data processor is designed especially for the multiplication routine. Several ternary optical operators are constructed to perform M transformations and summations in parallel, which has accelerated the iterative process of multiplication. In particular, the routine allocates data bits of the ternary optical processor based on digits of multiplication input, so the accuracy of the calculation results can always satisfy the users. Finally, the routine is verified by simulation experiments, and the results are in full compliance with the expectations. Compared with an electronic computer, the MSD multiplication routine is not only good at dealing with large-value data and high-precision arithmetic, but also maintains lower power consumption and fewer calculating delays.

  18. Automatic differentiation for design sensitivity analysis of structural systems using multiple processors

    Science.gov (United States)

    Nguyen, Duc T.; Storaasli, Olaf O.; Qin, Jiangning; Qamar, Ramzi

    1994-01-01

    An automatic differentiation tool (ADIFOR) is incorporated into a finite element based structural analysis program for shape and non-shape design sensitivity analysis of structural systems. The entire analysis and sensitivity procedures are parallelized and vectorized for high performance computation. Small scale examples to verify the accuracy of the proposed program and a medium scale example to demonstrate the parallel vector performance on multiple CRAY C90 processors are included.

  19. Collaborative E-Learning with Multiple Imaginary Co-Learner: Design, Issues and Implementation

    OpenAIRE

    Melvin Ballera; Mosbah Mohamed Elssaedi; Ahmed Khalil Zohdy

    2013-01-01

    Collaborative problem solving in e-learning can take in the form of discussion among learner, creating a highly social learning environment and characterized by participation and interactivity. This paper, designed a collaborative learning environment where agent act as co-learner, can play different roles during interaction. Since different roles have been assigned to the agent, learner will assume that multiple co-learner exists to help and guide him all throughout the ...

  20. Radar Precoder Design for Spectral Coexistence with Coordinated Multi-point (CoMP) System

    OpenAIRE

    Mahal, Jasmin A.; Khawar, Awais; Abdelhadi, Ahmed; Clancy, T. Charles

    2015-01-01

    This paper details the design of precoders for a MIMO radar spectrally coexistent with a MIMO cellular network. We focus on a coordinated multi-point (CoMP) system where a cluster of base stations (BSs) coordinate their transmissions to the intended user. The radar operates in two modes, interference-mitigation mode when it avoids interference with the CoMP system and cooperation mode when it exchanges information with it. Using either the conventional Switched Null Space Projection (SNSP) or...

  1. Design and Analysis of Cooperative Cable Parallel Manipulators for Multiple Mobile Cranes

    Directory of Open Access Journals (Sweden)

    Bin Zi

    2012-11-01

    Full Text Available The design, dynamic modelling, and workspace are presented in this paper concerning cooperative cable parallel manipulators for multiple mobile cranes (CPMMCs. The CPMMCs can handle complex tasks that are more difficult or even impossible for a single mobile crane. Kinematics and dynamics of the CPMMCs are studied on the basis of geometric methodology and d'Alembert's principle, and a mathematical model of the CPMMCs is developed and presented with dynamic simulation. The constant orientation workspace analysis of the CPMMCs is carried out additionally. As an example, a cooperative cable parallel manipulator for triple mobile cranes with 6 Degrees of Freedom is investigated on the basis of the above design objectives.

  2. A location-based multiple point statistics method: modelling the reservoir with non-stationary characteristics

    Directory of Open Access Journals (Sweden)

    Yin Yanshu

    2017-12-01

    Full Text Available In this paper, a location-based multiple point statistics method is developed to model a non-stationary reservoir. The proposed method characterizes the relationship between the sedimentary pattern and the deposit location using the relative central position distance function, which alleviates the requirement that the training image and the simulated grids have the same dimension. The weights in every direction of the distance function can be changed to characterize the reservoir heterogeneity in various directions. The local integral replacements of data events, structured random path, distance tolerance and multi-grid strategy are applied to reproduce the sedimentary patterns and obtain a more realistic result. This method is compared with the traditional Snesim method using a synthesized 3-D training image of Poyang Lake and a reservoir model of Shengli Oilfield in China. The results indicate that the new method can reproduce the non-stationary characteristics better than the traditional method and is more suitable for simulation of delta-front deposits. These results show that the new method is a powerful tool for modelling a reservoir with non-stationary characteristics.

  3. An Application of Graphical Approach to Construct Multiple Testing Procedure in a Hypothetical Phase III Design

    Directory of Open Access Journals (Sweden)

    Naitee eTing

    2014-01-01

    Full Text Available Many multiple testing procedures (MTP have been developed in recent years. Among these new procedures, the graphical approach is flexible and easy to communicate with non-statisticians. A hypothetical Phase III clinical trial design is introduced in this manuscript to demonstrate how graphical approach can be applied in clinical product development. In this design, an active comparator is used. It is thought that this test drug under development could potentially be superior to this comparator. For comparison of efficacy, the primary endpoint is well established and widely accepted by regulatory agencies. However, an important secondary endpoint based on Phase II findings looks very promising. The target dose may have a good opportunity to deliver superiority to the comparator. Furthermore, a lower dose is included in case the target dose may demonstrate potential safety concerns. This Phase III study is designed as a non-inferiority trial with two doses, and two endpoints. This manuscript will illustrate how graphical approach is applied to this design in handling multiple testing issues.

  4. Performance comparison of liquid metal and gas cooled ATW system point designs

    International Nuclear Information System (INIS)

    Yang, W.S.; Taiwo, T.A.; Hill, R.N.; Khalil, H.S.; Wade, D.C.

    2001-01-01

    As part of the Advanced Accelerator Application (AAA) program in the U.S., preliminary design studies have been performed at Argonne National Laboratory (ANL) and Los Alamos National Laboratory (LANL) to define and compare candidate Accelerator Transmutation of Waste (ATW) systems. The studies at ANL have focused primarily on the transmutation blanket component of the overall system. Lead-bismuth eutectic (LBE), sodium, and gas cooled systems are among the blanket technology options currently under consideration. This paper summarizes the results from neutronics trade studies performed at ANL. Core designs have been developed for LBE and sodium cooled 840 MWt fast spectrum accelerator driven systems employing re-cycle. Additionally, neutronics analyses have been performed for a helium-cooled 600 MWt hybrid thermal and fast spectrum system proposed by General Atomics (GA), which is operated in the critical mode for three cycles and in a subcritical accelerator driven mode for a subsequent single cycle. For these three point designs, isotopic inventories, consumption rates, and annual burnup rates are compared. The mass flows and the ultimate loss of transuranic (TRU) isotopes to the waste stream per unit of heat generated during transmutation are also compared on a consistent basis. (author)

  5. An intelligent, knowledge-based multiple criteria decision making advisor for systems design

    Science.gov (United States)

    Li, Yongchang

    In systems engineering, design and operation of systems are two main problems which always attract researcher's attentions. The accomplishment of activities in these problems often requires proper decisions to be made so that the desired goal can be achieved, thus, decision making needs to be carefully fulfilled in the design and operation of systems. Design is a decision making process which permeates through out the design process, and is at the core of all design activities. In modern aircraft design, more and more attention is paid to the conceptual and preliminary design phases so as to increase the odds of choosing a design that will ultimately be successful at the completion of the design process, therefore, decisions made during these early design stages play a critical role in determining the success of a design. Since aerospace systems are complex systems with interacting disciplines and technologies, the Decision Makers (DMs) dealing with such design problems are involved in balancing the multiple, potentially conflicting attributes/criteria, transforming a large amount of customer supplied guidelines into a solidly defined set of requirement definitions. Thus, one could state with confidence that modern aerospace system design is a Multiple Criteria Decision Making (MCDM) process. A variety of existing decision making methods are available to deal with this type of decision problems. The selection of the most appropriate decision making method is of particular importance since inappropriate decision methods are likely causes of misleading engineering design decisions. With no sufficient knowledge about each of the methods, it is usually difficult for the DMs to find an appropriate analytical model capable of solving their problems. In addition, with the complexity of the decision problem and the demand for more capable methods increasing, new decision making methods are emerging with time. These various methods exacerbate the difficulty of the selection

  6. A note on “An alternative multiple attribute decision making methodology for solving optimal facility layout design selection problems”

    OpenAIRE

    R. Venkata Rao

    2012-01-01

    A paper published by Maniya and Bhatt (2011) (An alternative multiple attribute decision making methodology for solving optimal facility layout design selection problems, Computers & Industrial Engineering, 61, 542-549) proposed an alternative multiple attribute decision making method named as “Preference Selection Index (PSI) method” for selection of an optimal facility layout design. The authors had claimed that the method was logical and more appropriate and the method gives directly the o...

  7. Data Base Design with GIS in Ecosystem Based Multiple Use Forest Management in Artvin, Turkey: A Case Study in Balcı Forest Management Planning Unit.

    Science.gov (United States)

    Yolasığmaz, Hacı Ahmet; Keleş, Sedat

    2009-01-01

    In Turkey, the understanding of planning focused on timber production has given its place on Multiple Use Management (MUM). Because the whole infrastructure of forestry with inventory system leading the way depends on timber production, some cases of bottle neck are expected during the transition period. Database design, probably the most important stage during the transition to MUM, together with the digital basic maps making up the basis of this infrastructure constitute the main point of this article. Firstly, the forest management philosophy of Turkey in the past was shortly touched upon in the article. Ecosystem Based Multiple Use Forest Management (EBMUFM) approaches was briefly introduced. The second stage of the process of EBMUFM, database design was described by examining the classical planning infrastructure and the coverage to be produced and consumed were suggested in the form of lists. At the application stage, two different geographical databases were established with GIS in Balcı Planning Unit of the years 1984 and 2006. Following that the related basic maps are produced. Timely diversity of the planning unit of 20 years is put forward comparatively with regard to the stand parameters such as tree types, age class, development stage, canopy closure, mixture, volume and increment.

  8. Fixed-Point Configurable Hardware Components

    Directory of Open Access Journals (Sweden)

    Rocher Romuald

    2006-01-01

    Full Text Available To reduce the gap between the VLSI technology capability and the designer productivity, design reuse based on IP (intellectual properties is commonly used. In terms of arithmetic accuracy, the generated architecture can generally only be configured through the input and output word lengths. In this paper, a new kind of method to optimize fixed-point arithmetic IP has been proposed. The architecture cost is minimized under accuracy constraints defined by the user. Our approach allows exploring the fixed-point search space and the algorithm-level search space to select the optimized structure and fixed-point specification. To significantly reduce the optimization and design times, analytical models are used for the fixed-point optimization process.

  9. SharePoint 2010 Development For Dummies

    CERN Document Server

    Withee, Ken

    2011-01-01

    A much-needed guide that shows you how to leverage SharePoint tools without writing a line of code!. The great news about SharePoint is…you don't need to be a seasoned .NET developer to develop custom functions for it. This book shows you how to use SharePoint Designer, Report Builder, Dashboard Designer, InfoPath, Excel, Word, Visio, and the SharePoint web-based UI to design and develop—without ever writing a line of code! Learn how to customize your site, build SharePoint apps, start social networking, or add Web parts.  This straightforward guide makes everything easier.: Introduces you to

  10. PC-based Multiple Information System Interface (PC/MISI) detailed design and implementation plan

    Science.gov (United States)

    Dominick, Wayne D. (Editor); Hall, Philip P.

    1985-01-01

    The design plan for the personal computer multiple information system interface (PC/MISI) project is discussed. The document is intended to be used as a blueprint for the implementation of the system. Each component is described in the detail necessary to allow programmers to implement the system. A description of the system data flow and system file structures is given.

  11. System Identification of a Heaving Point Absorber: Design of Experiment and Device Modeling

    Directory of Open Access Journals (Sweden)

    Giorgio Bacelli

    2017-04-01

    Full Text Available Empirically based modeling is an essential aspect of design for a wave energy converter. Empirically based models are used in structural, mechanical and control design processes, as well as for performance prediction. Both the design of experiments and methods used in system identification have a strong impact on the quality of the resulting model. This study considers the system identification and model validation process based on data collected from a wave tank test of a model-scale wave energy converter. Experimental design and data processing techniques based on general system identification procedures are discussed and compared with the practices often followed for wave tank testing. The general system identification processes are shown to have a number of advantages, including an increased signal-to-noise ratio, reduced experimental time and higher frequency resolution. The experimental wave tank data is used to produce multiple models using different formulations to represent the dynamics of the wave energy converter. These models are validated and their performance is compared against one another. While most models of wave energy converters use a formulation with surface elevation as an input, this study shows that a model using a hull pressure measurement to incorporate the wave excitation phenomenon has better accuracy.

  12. Paper-Based Digital Microfluidic Chip for Multiple Electrochemical Assay Operated by a Wireless Portable Control System

    DEFF Research Database (Denmark)

    Ruecha, Nipapan; Lee, Jumi; Chae, Heedo

    2017-01-01

    for multiple analysis assays are fabricated by affordable printing techniques. For enhanced sensitivity of the sensor, the working electrode is modified through the electrochemical method, namely by reducing graphene with voltammetry and coating gold nanoparticles by amperometry. Detachable sensor and absorber...... designed portable power supply and wireless control system, the active paper-based chip platform can be utilized as an advanced point-of-care device for multiple assays in digital microfluidics....

  13. Boiling points of halogenated ethanes: an explanatory model implicating weak intermolecular hydrogen-halogen bonding.

    Science.gov (United States)

    Beauchamp, Guy

    2008-10-23

    This study explores via structural clues the influence of weak intermolecular hydrogen-halogen bonds on the boiling point of halogenated ethanes. The plot of boiling points of 86 halogenated ethanes versus the molar refraction (linked to polarizability) reveals a series of straight lines, each corresponding to one of nine possible arrangements of hydrogen and halogen atoms on the two-carbon skeleton. A multiple linear regression model of the boiling points could be designed based on molar refraction and subgroup structure as independent variables (R(2) = 0.995, standard error of boiling point 4.2 degrees C). The model is discussed in view of the fact that molar refraction can account for approximately 83.0% of the observed variation in boiling point, while 16.5% could be ascribed to weak C-X...H-C intermolecular interactions. The difference in the observed boiling point of molecules having similar molar refraction values but differing in hydrogen-halogen intermolecular bonds can reach as much as 90 degrees C.

  14. Evaluation of biases present in the cohort multiple randomised controlled trial design : a simulation study

    NARCIS (Netherlands)

    Candlish, Jane; Pate, Alexander; Sperrin, Matthew; Staa, Tjeerd P van

    2017-01-01

    BACKGROUND: The cohort multiple randomised controlled trial (cmRCT) design provides an opportunity to incorporate the benefits of randomisation within clinical practice; thus reducing costs, integrating electronic healthcare records, and improving external validity. This study aims to address a key

  15. Common pitfalls in statistical analysis: The perils of multiple testing

    Science.gov (United States)

    Ranganathan, Priya; Pramesh, C. S.; Buyse, Marc

    2016-01-01

    Multiple testing refers to situations where a dataset is subjected to statistical testing multiple times - either at multiple time-points or through multiple subgroups or for multiple end-points. This amplifies the probability of a false-positive finding. In this article, we look at the consequences of multiple testing and explore various methods to deal with this issue. PMID:27141478

  16. Coexisting multiple attractors and riddled basins of a memristive system.

    Science.gov (United States)

    Wang, Guangyi; Yuan, Fang; Chen, Guanrong; Zhang, Yu

    2018-01-01

    In this paper, a new memristor-based chaotic system is designed, analyzed, and implemented. Multistability, multiple attractors, and complex riddled basins are observed from the system, which are investigated along with other dynamical behaviors such as equilibrium points and their stabilities, symmetrical bifurcation diagrams, and sustained chaotic states. With different sets of system parameters, the system can also generate various multi-scroll attractors. Finally, the system is realized by experimental circuits.

  17. Timelines Revisited: A Design Space and Considerations for Expressive Storytelling.

    Science.gov (United States)

    Brehmer, Matthew; Lee, Bongshin; Bach, Benjamin; Riche, Nathalie Henry; Munzner, Tamara

    2017-09-01

    There are many ways to visualize event sequences as timelines. In a storytelling context where the intent is to convey multiple narrative points, a richer set of timeline designs may be more appropriate than the narrow range that has been used for exploratory data analysis by the research community. Informed by a survey of 263 timelines, we present a design space for storytelling with timelines that balances expressiveness and effectiveness, identifying 14 design choices characterized by three dimensions: representation, scale, and layout. Twenty combinations of these choices are viable timeline designs that can be matched to different narrative points, while smooth animated transitions between narrative points allow for the presentation of a cohesive story, an important aspect of both interactive storytelling and data videos. We further validate this design space by realizing the full set of viable timeline designs and transitions in a proof-of-concept sandbox implementation that we used to produce seven example timeline stories. Ultimately, this work is intended to inform and inspire the design of future tools for storytelling with timelines.

  18. Democratizing rendering for multiple viewers in surround VR systems

    KAUST Repository

    Schulze, Jü rgen P.; Acevedo-Feliz, Daniel; Mangan, John; Prudhomme, Andrew; Nguyen, Phi Khanh; Weber, Philip P.

    2012-01-01

    We present a new approach for how multiple users' views can be rendered in a surround virtual environment without using special multi-view hardware. It is based on the idea that different parts of the screen are often viewed by different users, so that they can be rendered from their own view point, or at least from a point closer to their view point than traditionally expected. The vast majority of 3D virtual reality systems are designed for one head-tracked user, and a number of passive viewers. Only the head tracked user gets to see the correct view of the scene, everybody else sees a distorted image. We reduce this problem by algorithmically democratizing the rendering view point among all tracked users. Researchers have proposed solutions for multiple tracked users, but most of them require major changes to the display hardware of the VR system, such as additional projectors or custom VR glasses. Our approach does not require additional hardware, except the ability to track each participating user. We propose three versions of our multi-viewer algorithm. Each of them balances image distortion and frame rate in different ways, making them more or less suitable for certain application scenarios. Our most sophisticated algorithm renders each pixel from its own, optimized camera perspective, which depends on all tracked users' head positions and orientations. © 2012 IEEE.

  19. Democratizing rendering for multiple viewers in surround VR systems

    KAUST Repository

    Schulze, Jürgen P.

    2012-03-01

    We present a new approach for how multiple users\\' views can be rendered in a surround virtual environment without using special multi-view hardware. It is based on the idea that different parts of the screen are often viewed by different users, so that they can be rendered from their own view point, or at least from a point closer to their view point than traditionally expected. The vast majority of 3D virtual reality systems are designed for one head-tracked user, and a number of passive viewers. Only the head tracked user gets to see the correct view of the scene, everybody else sees a distorted image. We reduce this problem by algorithmically democratizing the rendering view point among all tracked users. Researchers have proposed solutions for multiple tracked users, but most of them require major changes to the display hardware of the VR system, such as additional projectors or custom VR glasses. Our approach does not require additional hardware, except the ability to track each participating user. We propose three versions of our multi-viewer algorithm. Each of them balances image distortion and frame rate in different ways, making them more or less suitable for certain application scenarios. Our most sophisticated algorithm renders each pixel from its own, optimized camera perspective, which depends on all tracked users\\' head positions and orientations. © 2012 IEEE.

  20. Conservatism implications of shock test tailoring for multiple design environments

    Science.gov (United States)

    Baca, Thomas J.; Bell, R. Glenn; Robbins, Susan A.

    1987-01-01

    A method for analyzing shock conservation in test specifications that have been tailored to qualify a structure for multiple design environments is discussed. Shock test conservation is qualified for shock response spectra, shock intensity spectra and ranked peak acceleration data in terms of an Index of Conservation (IOC) and an Overtest Factor (OTF). The multi-environment conservation analysis addresses the issue of both absolute and average conservation. The method is demonstrated in a case where four laboratory tests have been specified to qualify a component which must survive seven different field environments. Final judgment of the tailored test specification is shown to require an understanding of the predominant failure modes of the test item.

  1. A MARKED POINT PROCESS MODEL FOR VEHICLE DETECTION IN AERIAL LIDAR POINT CLOUDS

    Directory of Open Access Journals (Sweden)

    A. Börcs

    2012-07-01

    Full Text Available In this paper we present an automated method for vehicle detection in LiDAR point clouds of crowded urban areas collected from an aerial platform. We assume that the input cloud is unordered, but it contains additional intensity and return number information which are jointly exploited by the proposed solution. Firstly, the 3-D point set is segmented into ground, vehicle, building roof, vegetation and clutter classes. Then the points with the corresponding class labels and intensity values are projected to the ground plane, where the optimal vehicle configuration is described by a Marked Point Process (MPP model of 2-D rectangles. Finally, the Multiple Birth and Death algorithm is utilized to find the configuration with the highest confidence.

  2. Observer-based design of set-point tracking adaptive controllers for nonlinear chaotic systems

    International Nuclear Information System (INIS)

    Khaki-Sedigh, A.; Yazdanpanah-Goharrizi, A.

    2006-01-01

    A gradient based approach for the design of set-point tracking adaptive controllers for nonlinear chaotic systems is presented. In this approach, Lyapunov exponents are used to select the controller gain. In the case of unknown or time varying chaotic plants, the Lyapunov exponents may vary during the plant operation. In this paper, an effective adaptive strategy is used for online identification of Lyapunov exponents and adaptive control of nonlinear chaotic plants. Also, a nonlinear observer for estimation of the states is proposed. Simulation results are provided to show the effectiveness of the proposed methodology

  3. Observer-based design of set-point tracking adaptive controllers for nonlinear chaotic systems

    Energy Technology Data Exchange (ETDEWEB)

    Khaki-Sedigh, A. [Department of Electrical Engineering, K.N. Toosi University of Technology, Sayyed Khandan Bridge, Shariati Street, Tehran 16314 (Iran, Islamic Republic of)]. E-mail: sedigh@kntu.ac.ir; Yazdanpanah-Goharrizi, A. [Department of Electrical Engineering, K.N. Toosi University of Technology, Sayyed Khandan Bridge, Shariati Street, Tehran 16314 (Iran, Islamic Republic of)]. E-mail: yazdanpanah@ee.kntu.ac.ir

    2006-09-15

    A gradient based approach for the design of set-point tracking adaptive controllers for nonlinear chaotic systems is presented. In this approach, Lyapunov exponents are used to select the controller gain. In the case of unknown or time varying chaotic plants, the Lyapunov exponents may vary during the plant operation. In this paper, an effective adaptive strategy is used for online identification of Lyapunov exponents and adaptive control of nonlinear chaotic plants. Also, a nonlinear observer for estimation of the states is proposed. Simulation results are provided to show the effectiveness of the proposed methodology.

  4. Analysis, Design, and Construction of a Base-Isolated Multiple Building Structure

    Directory of Open Access Journals (Sweden)

    Stefano Sorace

    2014-01-01

    Full Text Available The analysis and design of a multiple residential building, seismically protected by a base isolation system incorporating double friction pendulum sliders as protective devices, are presented in the paper. The building, situated in the suburban area of Florence, is composed of four independent reinforced concrete framed structures, mutually separated by three thermal expansion joints. The plan is L-shaped, with dimensions of about 75 m in the longitudinal direction and about 30 m along the longest side of the transversal direction. These characteristics identify the structure as the largest example of a base-isolated “artificial ground” ever built in Italy. The base isolation solution guarantees lower costs, a much greater performance, and a finer architectural look, as compared to a conventional fixed-base antiseismic design. The characteristics of the building and the isolators, the mechanical properties and the experimental characterization campaign and preliminary sizing carried out on the latter, and the nonlinear time-history design and performance assessment analyses developed on the base isolated building are reported in this paper, along with details about the installation of the isolators and the plants and highlights of the construction works.

  5. Incorporating 3D-printing technology in the design of head-caps and electrode drives for recording neurons in multiple brain regions.

    Science.gov (United States)

    Headley, Drew B; DeLucca, Michael V; Haufler, Darrell; Paré, Denis

    2015-04-01

    Recent advances in recording and computing hardware have enabled laboratories to record the electrical activity of multiple brain regions simultaneously. Lagging behind these technical advances, however, are the methods needed to rapidly produce microdrives and head-caps that can flexibly accommodate different recording configurations. Indeed, most available designs target single or adjacent brain regions, and, if multiple sites are targeted, specially constructed head-caps are used. Here, we present a novel design style, for both microdrives and head-caps, which takes advantage of three-dimensional printing technology. This design facilitates targeting of multiple brain regions in various configurations. Moreover, the parts are easily fabricated in large quantities, with only minor hand-tooling and finishing required. Copyright © 2015 the American Physiological Society.

  6. On the Required Number of Antennas in a Point-to-Point Large-but-Finite MIMO System

    KAUST Repository

    Makki, Behrooz; Svensson, Tommy; Eriksson, Thomas; Alouini, Mohamed-Slim

    2015-01-01

    In this paper, we investigate the performance of the point-to-point multiple-input-multiple-output (MIMO) systems in the presence of a large but finite numbers of antennas at the transmitters and/or receivers. Considering the cases with and without hybrid automatic repeat request (HARQ) feedback, we determine the minimum numbers of the transmit/receive antennas which are required to satisfy different outage probability constraints. We study the effect of the spatial correlation between the antennas on the system performance. Also, the required number of antennas are obtained for different fading conditions. Our results show that different outage requirements can be satisfied with relatively few transmit/receive antennas. © 2015 IEEE.

  7. On the Required Number of Antennas in a Point-to-Point Large-but-Finite MIMO System

    KAUST Repository

    Makki, Behrooz

    2015-11-12

    In this paper, we investigate the performance of the point-to-point multiple-input-multiple-output (MIMO) systems in the presence of a large but finite numbers of antennas at the transmitters and/or receivers. Considering the cases with and without hybrid automatic repeat request (HARQ) feedback, we determine the minimum numbers of the transmit/receive antennas which are required to satisfy different outage probability constraints. We study the effect of the spatial correlation between the antennas on the system performance. Also, the required number of antennas are obtained for different fading conditions. Our results show that different outage requirements can be satisfied with relatively few transmit/receive antennas. © 2015 IEEE.

  8. Multiple active myofascial trigger points and pressure pain sensitivity maps in the temporalis muscle are related in women with chronic tension type headache.

    Science.gov (United States)

    Fernández-de-las-Peñas, César; Caminero, Ana B; Madeleine, Pascal; Guillem-Mesado, Amparo; Ge, Hong-You; Arendt-Nielsen, Lars; Pareja, Juan A

    2009-01-01

    To describe the common locations of active trigger points (TrPs) in the temporalis muscle and their referred pain patterns in chronic tension type headache (CTTH), and to determine if pressure sensitivity maps of this muscle can be used to describe the spatial distribution of active TrPs. Forty women with CTTH were included. An electronic pressure algometer was used to assess pressure pain thresholds (PPT) from 9 points over each temporalis muscle: 3 points in the anterior, medial and posterior part, respectively. Both muscles were examined for the presence of active TrPs over each of the 9 points. The referred pain pattern of each active TrP was assessed. Two-way analysis of variance detected significant differences in mean PPT levels between the measurement points (F=30.3; P<0.001), but not between sides (F=2.1; P=0.2). PPT scores decreased from the posterior to the anterior column (P<0.001). No differences were found in the number of active TrPs (F=0.3; P=0.9) between the dominant side the nondominant side. Significant differences were found in the distribution of the active TrPs (chi2=12.2; P<0.001): active TrPs were mostly found in the anterior column and in the middle of the muscle belly. The analysis of variance did not detect significant differences in the referred pain pattern between active TrPs (F=1.1, P=0.4). The topographical pressure pain sensitivity maps showed the distinct distribution of the TrPs indicated by locations with low PPTs. Multiple active TrPs in the temporalis muscle were found, particularly in the anterior column and in the middle of the muscle belly. Bilateral posterior to anterior decreased distribution of PPTs in the temporalis muscle in women with CTTH was found. The locations of active TrPs in the temporalis muscle corresponded well to the muscle areas with lower PPT, supporting the relationship between multiple active muscle TrPs and topographical pressure sensitivity maps in the temporalis muscle in women with CTTH.

  9. Design and Control of a Multiple Input DC/DC Converter for Battery/Ultra-capacitor Based Electric Vehicle Power System

    DEFF Research Database (Denmark)

    Schaltz, Erik; Li, Zhihao; Onar, Omer

    2009-01-01

    Battery/Ultra-capacitor based electrical vehicles (EV) combine two energy sources with different voltage levels and current characteristics. This paper focuses on design and control of a multiple input DC/DC converter, to regulate output voltage from different inputs. The proposed multi-input con......Battery/Ultra-capacitor based electrical vehicles (EV) combine two energy sources with different voltage levels and current characteristics. This paper focuses on design and control of a multiple input DC/DC converter, to regulate output voltage from different inputs. The proposed multi...

  10. Conceptual design of multiple parallel switching controller

    International Nuclear Information System (INIS)

    Ugolini, D.; Yoshikawa, S.; Ozawa, K.

    1996-01-01

    This paper discusses the conceptual design and the development of a preliminary model of a multiple parallel switching (MPS) controller. The introduction of several advanced controllers has widened and improved the control capability of nonlinear dynamical systems. However, it is not possible to uniquely define a controller that always outperforms the others, and, in many situations, the controller providing the best control action depends on the operating conditions and on the intrinsic properties and behavior of the controlled dynamical system. The desire to combine the control action of several controllers with the purpose to continuously attain the best control action has motivated the development of the MPS controller. The MPS controller consists of a number of single controllers acting in parallel and of an artificial intelligence (AI) based selecting mechanism. The AI selecting mechanism analyzes the output of each controller and implements the one providing the best control performance. An inherent property of the MPS controller is the possibility to discard unreliable controllers while still being able to perform the control action. To demonstrate the feasibility and the capability of the MPS controller the simulation of the on-line operation control of a fast breeder reactor (FBR) evaporator is presented. (author)

  11. Trans-disciplinarity: The Singularities and Multiplicities of Architecture

    Directory of Open Access Journals (Sweden)

    Tahl Kaminer

    2007-10-01

    Full Text Available This inaugural issue of Footprint aims at understanding today’s architecture culture as a negotiation between two antithetical definitions of architecture’s identity. The belief in the disciplinary singularity of architectural objects, irreducible to the conditions of their production, is confronted - in discourse and design - with the perception of architecture as an interdisciplinary mediation between multiple political, economic, social, technological and cultural factors. With the concept of trans-disciplinarity, the negotiation between these two positions is investigated here as an engine of the ‘tradition of the present’ of contemporary architecture - the discourses and designs which emerged in the 1960s and defined orientation points for today’s architectural thought and practice.

  12. Trans-disciplinarity: The Singularities and Multiplicities of Architecture

    Directory of Open Access Journals (Sweden)

    Lukasz Stanek

    2014-07-01

    Full Text Available This inaugural issue of Footprint aims at understanding today’s architecture culture as a negotiation between two antithetical definitions of architecture’s identity. The belief in the disciplinary singularity of architectural objects, irreducible to the conditions of their production, is confronted – in discourse and design – with the perception of architecture as an interdisciplinary mediation between multiple political, economic, social, technological and cultural factors. With the concept of trans-disciplinarity, the negotiation between these two positions is investigated here as an engine of the ‘tradition of the present’ of contemporary architecture – the discourses and designs which emerged in the 1960s and defined orientation points for today’s architectural thought and practice.

  13. A Virtual Pivot Point MEMS Actuator with Externally Mounted Mirror: Design, Fabrication and Characterization

    Directory of Open Access Journals (Sweden)

    T. M. Fahim AMIN

    2014-12-01

    Full Text Available In this paper, the design, fabrication, and characterization of a virtual pivot point micro electromechanical systems (MEMS electrostatic actuator with externally mounted mirror is presented. The point of rotation of the movable arm of the actuator is distant from the physical actuator. This is a requirement for certain applications, such as an external cavity laser in Littman configuration. A maximum rotational radius of 5 mm from the virtual pivot point was achieved. A detailed analytical analysis for the displacement of the structure is presented. The dynamic characterization of the device with a finite element analysis simulation shows that the resonance frequency of the in-plane rotational mode is well separated from that of the out-of-plane bending mode, confirming high in-plane stability. The devices were fabricated on a silicon-on-insulator wafer with device layer thickness of 100 µm. Thin mirrors were fabricated by dicing a 100 µm thick silicon wafer. A resonance frequency of about 5.9 ´ 102 Hz for the maximum sized mounted mirror (1.7 mm ´ 100 µm ´ 1.0 mm was determined by optical characterization.

  14. Comparison of multiple support excitation solution techniques for piping systems

    International Nuclear Information System (INIS)

    Sterkel, H.P.; Leimbach, K.R.

    1980-01-01

    Design and analysis of nuclear power plant piping systems exposed to a variety of dynamic loads often require multiple support excitation analysis by modal or direct time integration methods. Both methods have recently been implemented in the computer program KWUROHR for static and dynamic analysis of piping systems, following the previous implementation of the multiple support excitation response spectrum method (see papers K 6/15 and K 6/15a of the SMiRT-4 Conference). The results of multiple support excitation response spectrum analyses can be examined by carrying out the equivalent time history analyses which do not distort the time phase relationship between the excitations at different support points. A frequent point of discussion is multiple versus single support excitation. A single support excitation analysis is computationally straightforward and tends to be on the conservative side, as the numerical results show. A multiple support excitation analysis, however, does not incur much more additional computer cost than the expenditure for an initial static solution involving three times the number, L, of excitation levels, i.e. 3L static load cases. The results are more realistic than those from a single support excitation analysis. A number of typical nuclear plant piping systems have been analyzed using single and multiple support excitation algorithms for: (1) the response spectrum method, (2) the modal time history method via the Wilson, Newmark and Goldberg integration operators and (3) the direct time history method via the Wilson integration operator. Characteristic results are presented to compare the computational quality of all three methods. (orig.)

  15. Predicting Harmonic Distortion of Multiple Converters in a Power System

    Directory of Open Access Journals (Sweden)

    P. M. Ivry

    2017-01-01

    Full Text Available Various uncertainties arise in the operation and management of power systems containing Renewable Energy Sources (RES that affect the systems power quality. These uncertainties may arise due to system parameter changes or design parameter choice. In this work, the impact of uncertainties on the prediction of harmonics in a power system containing multiple Voltage Source Converters (VSCs is investigated. The study focuses on the prediction of harmonic distortion level in multiple VSCs when some system or design parameters are only known within certain constraints. The Univariate Dimension Reduction (UDR method was utilized in this study as an efficient predictive tool for the level of harmonic distortion of the VSCs measured at the Point of Common Coupling (PCC to the grid. Two case studies were considered and the UDR technique was also experimentally validated. The obtained results were compared with that of the Monte Carlo Simulation (MCS results.

  16. More Than Just Accuracy: A Novel Method to Incorporate Multiple Test Attributes in Evaluating Diagnostic Tests Including Point of Care Tests.

    Science.gov (United States)

    Thompson, Matthew; Weigl, Bernhard; Fitzpatrick, Annette; Ide, Nicole

    2016-01-01

    Current frameworks for evaluating diagnostic tests are constrained by a focus on diagnostic accuracy, and assume that all aspects of the testing process and test attributes are discrete and equally important. Determining the balance between the benefits and harms associated with new or existing tests has been overlooked. Yet, this is critically important information for stakeholders involved in developing, testing, and implementing tests. This is particularly important for point of care tests (POCTs) where tradeoffs exist between numerous aspects of the testing process and test attributes. We developed a new model that multiple stakeholders (e.g., clinicians, patients, researchers, test developers, industry, regulators, and health care funders) can use to visualize the multiple attributes of tests, the interactions that occur between these attributes, and their impacts on health outcomes. We use multiple examples to illustrate interactions between test attributes (test availability, test experience, and test results) and outcomes, including several POCTs. The model could be used to prioritize research and development efforts, and inform regulatory submissions for new diagnostics. It could potentially provide a way to incorporate the relative weights that various subgroups or clinical settings might place on different test attributes. Our model provides a novel way that multiple stakeholders can use to visualize test attributes, their interactions, and impacts on individual and population outcomes. We anticipate that this will facilitate more informed decision making around diagnostic tests.

  17. Design of a smart textile mat to study pressure distribution on multiple foam material configurations

    NARCIS (Netherlands)

    Donselaar, van R.; Chen, W.

    2011-01-01

    In this paper, we present a design of a smart textile pressure mat to study the pressure distribution with multiple foam material configurations for neonatal monitoring at Neonatal Intensive Care Units (NICU). A smart textile mat with 64 pressure sensors has been developed including software at the

  18. Design and fabrication of a diffractive beam splitter for dual-wavelength and concurrent irradiation of process points.

    Science.gov (United States)

    Amako, Jun; Shinozaki, Yu

    2016-07-11

    We report on a dual-wavelength diffractive beam splitter designed for use in parallel laser processing. This novel optical element generates two beam arrays of different wavelengths and allows their overlap at the process points on a workpiece. To design the deep surface-relief profile of a splitter using a simulated annealing algorithm, we introduce a heuristic but practical scheme to determine the maximum depth and the number of quantization levels. The designed corrugations were fabricated in a photoresist by maskless grayscale exposure using a high-resolution spatial light modulator. We characterized the photoresist splitter, thereby validating the proposed beam-splitting concept.

  19. Multiple-Criteria Decision-Making in the Design of Innovative Lock Walls for Barge Impact; Phase 1

    National Research Council Canada - National Science Library

    Lambert, James

    2001-01-01

    .... This research project consists of two phases: Phase 1, which culminates with this report, investigated the use of multiple-criteria decision-making in the design process of lock approach walls to consider barge impact and earthquake loads...

  20. Multiple mononeuropathy

    Science.gov (United States)

    ... with multiple mononeuropathy are prone to new nerve injuries at pressure points such as the knees and elbows. They should avoid putting pressure on these areas, for example, by not leaning on the elbows, crossing the knees, ...

  1. Association of a novel point mutation in MSH2 gene with familial multiple primary cancers

    Directory of Open Access Journals (Sweden)

    Hai Hu

    2017-10-01

    Full Text Available Abstract Background Multiple primary cancers (MPC have been identified as two or more cancers without any subordinate relationship that occur either simultaneously or metachronously in the same or different organs of an individual. Lynch syndrome is an autosomal dominant genetic disorder that increases the risk of many types of cancers. Lynch syndrome patients who suffer more than two cancers can also be considered as MPC; patients of this kind provide unique resources to learn how genetic mutation causes MPC in different tissues. Methods We performed a whole genome sequencing on blood cells and two tumor samples of a Lynch syndrome patient who was diagnosed with five primary cancers. The mutational landscape of the tumors, including somatic point mutations and copy number alternations, was characterized. We also compared Lynch syndrome with sporadic cancers and proposed a model to illustrate the mutational process by which Lynch syndrome progresses to MPC. Results We revealed a novel pathologic mutation on the MSH2 gene (G504 splicing that associates with Lynch syndrome. Systematical comparison of the mutation landscape revealed that multiple cancers in the proband were evolutionarily independent. Integrative analysis showed that truncating mutations of DNA mismatch repair (MMR genes were significantly enriched in the patient. A mutation progress model that included germline mutations of MMR genes, double hits of MMR system, mutations in tissue-specific driver genes, and rapid accumulation of additional passenger mutations was proposed to illustrate how MPC occurs in Lynch syndrome patients. Conclusion Our findings demonstrate that both germline and somatic alterations are driving forces of carcinogenesis, which may resolve the carcinogenic theory of Lynch syndrome.

  2. Quantifying natural delta variability using a multiple-point geostatistics prior uncertainty model

    Science.gov (United States)

    Scheidt, Céline; Fernandes, Anjali M.; Paola, Chris; Caers, Jef

    2016-10-01

    We address the question of quantifying uncertainty associated with autogenic pattern variability in a channelized transport system by means of a modern geostatistical method. This question has considerable relevance for practical subsurface applications as well, particularly those related to uncertainty quantification relying on Bayesian approaches. Specifically, we show how the autogenic variability in a laboratory experiment can be represented and reproduced by a multiple-point geostatistical prior uncertainty model. The latter geostatistical method requires selection of a limited set of training images from which a possibly infinite set of geostatistical model realizations, mimicking the training image patterns, can be generated. To that end, we investigate two methods to determine how many training images and what training images should be provided to reproduce natural autogenic variability. The first method relies on distance-based clustering of overhead snapshots of the experiment; the second method relies on a rate of change quantification by means of a computer vision algorithm termed the demon algorithm. We show quantitatively that with either training image selection method, we can statistically reproduce the natural variability of the delta formed in the experiment. In addition, we study the nature of the patterns represented in the set of training images as a representation of the "eigenpatterns" of the natural system. The eigenpattern in the training image sets display patterns consistent with previous physical interpretations of the fundamental modes of this type of delta system: a highly channelized, incisional mode; a poorly channelized, depositional mode; and an intermediate mode between the two.

  3. Detecting change-points in extremes

    KAUST Repository

    Dupuis, D. J.

    2015-01-01

    Even though most work on change-point estimation focuses on changes in the mean, changes in the variance or in the tail distribution can lead to more extreme events. In this paper, we develop a new method of detecting and estimating the change-points in the tail of multiple time series data. In addition, we adapt existing tail change-point detection methods to our specific problem and conduct a thorough comparison of different methods in terms of performance on the estimation of change-points and computational time. We also examine three locations on the U.S. northeast coast and demonstrate that the methods are useful for identifying changes in seasonally extreme warm temperatures.

  4. Modeling low-thrust transfers between periodic orbits about five libration points: Manifolds and hierarchical design

    Science.gov (United States)

    Zeng, Hao; Zhang, Jingrui

    2018-04-01

    The low-thrust version of the fuel-optimal transfers between periodic orbits with different energies in the vicinity of five libration points is exploited deeply in the Circular Restricted Three-Body Problem. Indirect optimization technique incorporated with constraint gradients is employed to further improve the computational efficiency and accuracy of the algorithm. The required optimal thrust magnitude and direction can be determined to create the bridging trajectory that connects the invariant manifolds. A hierarchical design strategy dividing the constraint set is proposed to seek the optimal solution when the problem cannot be solved directly. Meanwhile, the solution procedure and the value ranges of used variables are summarized. To highlight the effectivity of the transfer scheme and aim at different types of libration point orbits, transfer trajectories between some sample orbits, including Lyapunov orbits, planar orbits, halo orbits, axial orbits, vertical orbits and butterfly orbits for collinear and triangular libration points, are investigated with various time of flight. Numerical results show that the fuel consumption varies from a few kilograms to tens of kilograms, related to the locations and the types of mission orbits as well as the corresponding invariant manifold structures, and indicates that the low-thrust transfers may be a beneficial option for the extended science missions around different libration points.

  5. SharePoint 2010 Enterprise Architect's Guidebook

    CERN Document Server

    Wilson, Brian; Baer, Bill; Kearn, Martin; Shah, Arpan; Adams, Jim; Bridport, Nigel; Esperanca, Huge; Gideon, Chris; Hassani, Sam; Hodgkinson, Neil; Juvonen, Vesa; Kleven, Scott; Morrish, Ian; Olenick, Paul; Ranlett, Matt; Voskresenskaya, Natalya; Walker, Simon; Whitehead, Chris

    2012-01-01

    Tips and techniques for becoming a successful SharePoint architect If you're eager to design and architect a successful deployment of SharePoint 2010, then this is the book for you. Packed with real-world experiences and solid processes, this guidebook provides you with everything you need to perform for designing and architecting enterprise portal services. Helpful examples examine the common design issues affecting SharePoint 2010 environments that can cause deployments to fail so you can learn what to avoid. Plus, key development and deployment issues are covered from an architecture perspe

  6. Implementing Target Value Design.

    Science.gov (United States)

    Alves, Thais da C L; Lichtig, Will; Rybkowski, Zofia K

    2017-04-01

    An alternative to the traditional way of designing projects is the process of target value design (TVD), which takes different departure points to start the design process. The TVD process starts with the client defining an allowable cost that needs to be met by the design and construction teams. An expected cost in the TVD process is defined through multiple interactions between multiple stakeholders who define wishes and others who define ways of achieving these wishes. Finally, a target cost is defined based on the expected profit the design and construction teams are expecting to make. TVD follows a series of continuous improvement efforts aimed at reaching the desired goals for the project and its associated target value cost. The process takes advantage of rapid cycles of suggestions, analyses, and implementation that starts with the definition of value for the client. In the traditional design process, the goal is to identify user preferences and find solutions that meet the needs of the client's expressed preferences. In the lean design process, the goal is to educate users about their values and advocate for a better facility over the long run; this way owners can help contractors and designers to identify better solutions. This article aims to inform the healthcare community about tools and techniques commonly used during the TVD process and how they can be used to educate and support project participants in developing better solutions to meet their needs now as well as in the future.

  7. Investigation of charge multiplication in single crystalline CVD diamond particle detectors

    Energy Technology Data Exchange (ETDEWEB)

    Muškinja, M.; Cindro, V.; Gorišek, A. [Jožef Stefan Institute, Jamova 39, SI-1000 Ljubljana (Slovenia); Kagan, H. [Department of Physics, Ohio State University (United States); Kramberger, G., E-mail: Gregor.Kramberger@ijs.si [Jožef Stefan Institute, Jamova 39, SI-1000 Ljubljana (Slovenia); Mandić, I. [Jožef Stefan Institute, Jamova 39, SI-1000 Ljubljana (Slovenia); Mikuž, M. [Jožef Stefan Institute, Jamova 39, SI-1000 Ljubljana (Slovenia); Faculty of Physics and Mathematics, University of Ljubljana (Slovenia); Phan, S.; Smith, D.S. [Department of Physics, Ohio State University (United States); Zavrtanik, M. [Jožef Stefan Institute, Jamova 39, SI-1000 Ljubljana (Slovenia)

    2017-01-01

    A special metallization pattern was created on a single crystalline diamond detector aimed at creating high enough electric field for impact ionization in the detector material. Electric field line focusing through electrode design and very high bias voltages were used to obtain high electric fields. Previous measurements and theoretical calculations indicated that drifting charge multiplication by impact ionization could take place. A large increase of induced charge was observed for the smallest dot electrode which points to charge multiplication while for the large dot and pad detector structure no such effect was observed. The evolution of induced currents was also monitored with the transient current technique. Induced current pulses with duration of order 1 μs were measured. The multiplication gain was found to depend on the particle rate.

  8. Eta Carinae: Viewed from Multiple Vantage Points

    Science.gov (United States)

    Gull, Theodore

    2007-01-01

    The central source of Eta Carinae and its ejecta is a massive binary system buried within a massive interacting wind structure which envelops the two stars. However the hot, less massive companion blows a small cavity in the very massive primary wind, plus ionizes a portion of the massive wind just beyond the wind-wind boundary. We gain insight on this complex structure by examining the spatially-resolved Space Telescope Imaging Spectrograph (STIS) spectra of the central source (0.1") with the wind structure which extends out to nearly an arcsecond (2300AU) and the wind-blown boundaries, plus the ejecta of the Little Homunculus. Moreover, the spatially resolved Very Large Telescope/UltraViolet Echelle Spectrograph (VLT/UVES) stellar spectrum (one arcsecond) and spatially sampled spectra across the foreground lobe of the Homunculus provide us vantage points from different angles relative to line of sight. Examples of wind line profiles of Fe II, and the.highly excited [Fe III], [Ne III], [Ar III] and [S III)], plus other lines will be presented.

  9. Fast underdetermined BSS architecture design methodology for real time applications.

    Science.gov (United States)

    Mopuri, Suresh; Reddy, P Sreenivasa; Acharyya, Amit; Naik, Ganesh R

    2015-01-01

    In this paper, we propose a high speed architecture design methodology for the Under-determined Blind Source Separation (UBSS) algorithm using our recently proposed high speed Discrete Hilbert Transform (DHT) targeting real time applications. In UBSS algorithm, unlike the typical BSS, the number of sensors are less than the number of the sources, which is of more interest in the real time applications. The DHT architecture has been implemented based on sub matrix multiplication method to compute M point DHT, which uses N point architecture recursively and where M is an integer multiples of N. The DHT architecture and state of the art architecture are coded in VHDL for 16 bit word length and ASIC implementation is carried out using UMC 90 - nm technology @V DD = 1V and @ 1MHZ clock frequency. The proposed architecture implementation and experimental comparison results show that the DHT design is two times faster than state of the art architecture.

  10. Sensitivity analysis of physical/operational parameters in neutron multiplicity counting

    International Nuclear Information System (INIS)

    Peerani, P.; Marin Ferrer, M.

    2007-01-01

    In this paper, we perform a sensitivity study on the influence of various physical and operational parameters on the results of neutron multiplicity counting. The purpose is to have a better understanding of the importance of each component and its contribution to the measurement uncertainty. Then we will be able to determine the optimal conditions for the operational parameters and for detector design and as well to point out weaknesses in the knowledge of critical fundamental nuclear data

  11. How to Construct a Mixed Methods Research Design.

    Science.gov (United States)

    Schoonenboom, Judith; Johnson, R Burke

    2017-01-01

    This article provides researchers with knowledge of how to design a high quality mixed methods research study. To design a mixed study, researchers must understand and carefully consider each of the dimensions of mixed methods design, and always keep an eye on the issue of validity. We explain the seven major design dimensions: purpose, theoretical drive, timing (simultaneity and dependency), point of integration, typological versus interactive design approaches, planned versus emergent design, and design complexity. There also are multiple secondary dimensions that need to be considered during the design process. We explain ten secondary dimensions of design to be considered for each research study. We also provide two case studies showing how the mixed designs were constructed.

  12. Online evaluation of point-of-interest recommendation systems

    NARCIS (Netherlands)

    Dean-Hall, A.; Clarke, C.L.A.; Kamps, J.; Kiseleva, J.

    2015-01-01

    In this work we describe a system to evaluate multiple point- of-interest recommendation systems. In this system each recommendation service will be exposed online and crowd-sourced assessors will interact with merged results from multiple services, which are responding to suggestion requests live,

  13. Three-dimensional cross point readout detector design for including depth information

    Science.gov (United States)

    Lee, Seung-Jae; Baek, Cheol-Ha

    2018-04-01

    We designed a depth-encoding positron emission tomography (PET) detector using a cross point readout method with wavelength-shifting (WLS) fibers. To evaluate the characteristics of the novel detector module and the PET system, we used the DETECT2000 to perform optical photon transport in the crystal array. The GATE was also used. The detector module is made up of four layers of scintillator arrays, the five layers of WLS fiber arrays, and two sensor arrays. The WLS fiber arrays in each layer cross each other to transport light to each sensor array. The two sensor arrays are coupled to the forward and left sides of the WLS fiber array, respectively. The identification of three-dimensional pixels was determined using a digital positioning algorithm. All pixels were well decoded, with the system resolution ranging from 2.11 mm to 2.29 mm at full width at half maximum (FWHM).

  14. Optimal design of a beam-based dynamic vibration absorber using fixed-points theory

    Science.gov (United States)

    Hua, Yingyu; Wong, Waion; Cheng, Li

    2018-05-01

    The addition of a dynamic vibration absorber (DVA) to a vibrating structure could provide an economic solution for vibration suppressions if the absorber is properly designed and located onto the structure. A common design of the DVA is a sprung mass because of its simple structure and low cost. However, the vibration suppression performance of this kind of DVA is limited by the ratio between the absorber mass and the mass of the primary structure. In this paper, a beam-based DVA (beam DVA) is proposed and optimized for minimizing the resonant vibration of a general structure. The vibration suppression performance of the proposed beam DVA depends on the mass ratio, the flexural rigidity and length of the beam. In comparison with the traditional sprung mass DVA, the proposed beam DVA shows more flexibility in vibration control design because it has more design parameters. With proper design, the beam DVA's vibration suppression capability can outperform that of the traditional DVA under the same mass constraint. The general approach is illustrated using a benchmark cantilever beam as an example. The receptance theory is introduced to model the compound system consisting of the host beam and the attached beam-based DVA. The model is validated through comparisons with the results from Abaqus as well as the Transfer Matrix method (TMM) method. Fixed-points theory is then employed to derive the analytical expressions for the optimum tuning ratio and damping ratio of the proposed beam absorber. A design guideline is then presented to choose the parameters of the beam absorber. Comparisons are finally presented between the beam absorber and the traditional DVA in terms of the vibration suppression effect. It is shown that the proposed beam absorber can outperform the traditional DVA by following this proposed guideline.

  15. Point-by-point written fiber-Bragg gratings and their application in complex grating designs.

    Science.gov (United States)

    Marshall, Graham D; Williams, Robert J; Jovanovic, Nemanja; Steel, M J; Withford, Michael J

    2010-09-13

    The point-by-point technique of fabricating fibre-Bragg gratings using an ultrafast laser enables complete control of the position of each index modification that comprises the grating. By tailoring the local phase, amplitude and spacing of the grating's refractive index modulations it is possible to create gratings with complex transmission and reflection spectra. We report a series of grating structures that were realized by exploiting these flexibilities. Such structures include gratings with controlled bandwidth, and amplitude- and phase-modulated sampled (or superstructured) gratings. A model based on coupled-mode theory provides important insights into the manufacture of such gratings. Our approach offers a quick and easy method of producing complex, non-uniform grating structures in both fibres and other mono-mode waveguiding structures.

  16. Kick-Off Point (KOP and End of Buildup (EOB Data Analysis in Trajectory Design

    Directory of Open Access Journals (Sweden)

    Novrianti Novrianti

    2017-06-01

    Full Text Available Well X is a development well which is directionally drilled. Directional drilling is choosen because the coordinate target of Well X is above the buffer zone. The directional track plan needs accurate survey calculation in order to make the righ track for directional drilling. There are many survey calculation in directional drilling such as tangential, underbalance, average angle, radius of curvature, and mercury method. Minimum curvature method is used in this directional track plan calculation. This method is used because it gives less error than other method.  Kick-Off Point (KOP and End of Buildup (EOB analysis is done at 200 ft, 400 ft, and 600 ft depth to determine the trajectory design and optimal inclination. The hole problem is also determined in this trajectory track design. Optimal trajectory design determined at 200 ft depth because the inclination below 35º and also already reach the target quite well at 1632.28 ft TVD and 408.16 AHD. The optimal inclination at 200 ft KOP depth because the maximum inclination is 18.87º which is below 35º. Hole problem will occur if the trajectory designed at 600 ft. The problems are stuck pipe and the casing or tubing will not able to bend.

  17. Designing Learning for Co-Creation

    DEFF Research Database (Denmark)

    Gnaur, Dorina; Larsen-Nielsen, Marie

    2017-01-01

    Designing learning for co-creation - conceptual and practical considerations, Dorina Gnaur and Inger Marie Larsen-Nielsen explore the practical educational point of view. The question they are posing themselves is: how can higher and further education (HE) educate for co-creation, that is, provide...... educational frameworks that respond to the societal demand for co-creation, particularly within the public welfare sector? First, they focus on which organisational and individual requirements an HE learning design should take into account in order to support the diffusion of co-creation competences....... Then they argue for the need to integrate these considerations in the learning design and demonstrate a practical application in the form of a didactical design. They call this a hybrid learning design, in that it takes advantage of technological developments to mediate co-creative learning in multiple learning...

  18. Set membership experimental design for biological systems

    Directory of Open Access Journals (Sweden)

    Marvel Skylar W

    2012-03-01

    Full Text Available Abstract Background Experimental design approaches for biological systems are needed to help conserve the limited resources that are allocated for performing experiments. The assumptions used when assigning probability density functions to characterize uncertainty in biological systems are unwarranted when only a small number of measurements can be obtained. In these situations, the uncertainty in biological systems is more appropriately characterized in a bounded-error context. Additionally, effort must be made to improve the connection between modelers and experimentalists by relating design metrics to biologically relevant information. Bounded-error experimental design approaches that can assess the impact of additional measurements on model uncertainty are needed to identify the most appropriate balance between the collection of data and the availability of resources. Results In this work we develop a bounded-error experimental design framework for nonlinear continuous-time systems when few data measurements are available. This approach leverages many of the recent advances in bounded-error parameter and state estimation methods that use interval analysis to generate parameter sets and state bounds consistent with uncertain data measurements. We devise a novel approach using set-based uncertainty propagation to estimate measurement ranges at candidate time points. We then use these estimated measurements at the candidate time points to evaluate which candidate measurements furthest reduce model uncertainty. A method for quickly combining multiple candidate time points is presented and allows for determining the effect of adding multiple measurements. Biologically relevant metrics are developed and used to predict when new data measurements should be acquired, which system components should be measured and how many additional measurements should be obtained. Conclusions The practicability of our approach is illustrated with a case study. This

  19. Concurrent airline fleet allocation and aircraft design with profit modeling for multiple airlines

    Science.gov (United States)

    Govindaraju, Parithi

    A "System of Systems" (SoS) approach is particularly beneficial in analyzing complex large scale systems comprised of numerous independent systems -- each capable of independent operations in their own right -- that when brought in conjunction offer capabilities and performance beyond the constituents of the individual systems. The variable resource allocation problem is a type of SoS problem, which includes the allocation of "yet-to-be-designed" systems in addition to existing resources and systems. The methodology presented here expands upon earlier work that demonstrated a decomposition approach that sought to simultaneously design a new aircraft and allocate this new aircraft along with existing aircraft in an effort to meet passenger demand at minimum fleet level operating cost for a single airline. The result of this describes important characteristics of the new aircraft. The ticket price model developed and implemented here enables analysis of the system using profit maximization studies instead of cost minimization. A multiobjective problem formulation has been implemented to determine characteristics of a new aircraft that maximizes the profit of multiple airlines to recognize the fact that aircraft manufacturers sell their aircraft to multiple customers and seldom design aircraft customized to a single airline's operations. The route network characteristics of two simple airlines serve as the example problem for the initial studies. The resulting problem formulation is a mixed-integer nonlinear programming problem, which is typically difficult to solve. A sequential decomposition strategy is applied as a solution methodology by segregating the allocation (integer programming) and aircraft design (non-linear programming) subspaces. After solving a simple problem considering two airlines, the decomposition approach is then applied to two larger airline route networks representing actual airline operations in the year 2005. The decomposition strategy serves

  20. Optical design of a Michelson wide-field multiple-aperture telescope

    Science.gov (United States)

    Cassaing, Frederic; Sorrente, Beatrice; Fleury, Bruno; Laubier, David

    2004-02-01

    Multiple-Aperture Optical Telescopes (MAOTs) are a promising solution for very high resolution imaging. In the Michelson configuration, the instrument is made of sub-telescopes distributed in the pupil and combined by a common telescope via folding periscopes. The phasing conditions of the sub-pupils lead to specific optical constraints in these subsystems. The amplitude of main contributors to the wavefront error (WFE) is given as a function of high level requirements (such as field or resolution) and free parameters, mainly the sub-telescope type, magnification and diameter. It is shown that for the periscopes, the field-to-resolution ratio is the main design driver and can lead to severe specifications. The effect of sub-telescopes aberrations on the global WFE can be minimized by reducing their diameter. An analytical tool for the MAOT design has been derived from this analysis, illustrated and validated in three different cases: LEO or GEO Earth observation and astronomy with extremely large telescopes. The last two cases show that a field larger than 10 000 resolution elements can be covered with a very simple MAOT based on Mersenne paraboloid-paraboloid sub-telescopes. Michelson MAOTs are thus a solution to be considered for high resolution wide-field imaging, from space or ground.

  1. Multidisciplinary Simulation of Graphite-Composite and Cermet Fuel Elements for NTP Point of Departure Designs

    Science.gov (United States)

    Stewart, Mark E.; Schnitzler, Bruce G.

    2015-01-01

    This paper compares the expected performance of two Nuclear Thermal Propulsion fuel types. High fidelity, fluid/thermal/structural + neutronic simulations help predict the performance of graphite-composite and cermet fuel types from point of departure engine designs from the Nuclear Thermal Propulsion project. Materials and nuclear reactivity issues are reviewed for each fuel type. Thermal/structural simulations predict thermal stresses in the fuel and thermal expansion mis-match stresses in the coatings. Fluid/thermal/structural/neutronic simulations provide predictions for full fuel elements. Although NTP engines will utilize many existing chemical engine components and technologies, nuclear fuel elements are a less developed engine component and introduce design uncertainty. Consequently, these fuel element simulations provide important insights into NTP engine performance.

  2. Testing of an End-Point Control Unit Designed to Enable Precision Control of Manipulator-Coupled Spacecraft

    Science.gov (United States)

    Montgomery, Raymond C.; Ghosh, Dave; Tobbe, Patrick A.; Weathers, John M.; Manouchehri, Davoud; Lindsay, Thomas S.

    1994-01-01

    This paper presents an end-point control concept designed to enable precision telerobotic control of manipulator-coupled spacecraft. The concept employs a hardware unit (end-point control unit EPCU) that is positioned between the end-effector of the Space Shuttle Remote Manipulator System and the payload. Features of the unit are active compliance (control of the displacement between the end-effector and the payload), to allow precision control of payload motions, and inertial load relief, to prevent the transmission of loads between the end-effector and the payload. This paper presents the concept and studies the active compliance feature using a simulation and hardware. Results of the simulation show the effectiveness of the EPCU in smoothing the motion of the payload. Results are presented from initial, limited tests of a laboratory hardware unit on a robotic arm testbed at the l Space Flight Center. Tracking performance of the arm in a constant speed automated retraction and extension maneuver of a heavy payload with and without the unit active is compared for the design speed and higher speeds. Simultaneous load reduction and tracking performance are demonstrated using the EPCU.

  3. Optical design of multi-multiple expander structure of laser gas analysis and measurement device

    Science.gov (United States)

    Fu, Xiang; Wei, Biao

    2018-03-01

    The installation and debugging of optical circuit structure in the application of carbon monoxide distributed laser gas analysis and measurement, there are difficult key technical problems. Based on the three-component expansion theory, multi-multiple expander structure with expansion ratio of 4, 5, 6 and 7 is adopted in the absorption chamber to enhance the adaptability of the installation environment of the gas analysis and measurement device. According to the basic theory of aberration, the optimal design of multi-multiple beam expander structure is carried out. By using image quality evaluation method, the difference of image quality under different magnifications is analyzed. The results show that the optical quality of the optical system with the expanded beam structure is the best when the expansion ratio is 5-7.

  4. Forces, surface finish and friction characteristics in surface engineered single- and multiple-point cutting edges

    International Nuclear Information System (INIS)

    Sarwar, M.; Gillibrand, D.; Bradbury, S.R.

    1991-01-01

    Advanced surface engineering technologies (physical and chemical vapour deposition) have been successfully applied to high speed steel and carbide cutting tools, and the potential benefits in terms of both performance and longer tool life, are now well established. Although major achievements have been reported by many manufacturers and users, there are a number of applications where surface engineering has been unsuccessful. Considerable attention has been given to the film characteristics and the variables associated with its properties; however, very little attention has been directed towards the benefits to the tool user. In order to apply surface engineering technology effectively to cutting tools, the coater needs to have accurate information relating to cutting conditions, i.e. cutting forces, stress and temperature etc. The present paper describes results obtained with single- and multiple-point cutting tools with examples of failures, which should help the surface coater to appreciate the significance of the cutting conditions, and in particular the magnitude of the forces and stresses present during cutting processes. These results will assist the development of a systems approach to cutting tool technology and surface engineering with a view to developing an improved product. (orig.)

  5. Optimization of advanced high-temperature Brayton cycles with multiple reheat stages

    International Nuclear Information System (INIS)

    Haihua Zhao; Per F Peterson

    2005-01-01

    Full text of publication follows: This paper presents an overview and a few point designs for multiple-reheat Brayton cycle power conversion systems using high temperature molten salts (or liquid metals). All designs are derived from the General Atomics GT-MHR power conversion unit (PCU). The GT-MHR PCU is currently the only closed helium cycle system that has undergone detailed engineering design analysis, and that has turbomachinery which is sufficiently large to extrapolate to a >1000 MW(e) multiple reheat gas cycle power conversion system. Analysis shows that, with relatively small engineering modifications, multiple GT-MHR PCU's can be connected together to create a power conversion system in the >1000 MW(e) class. The resulting power conversion system is quite compact, and results in what is likely the minimum gas duct volume possible for a multiple-reheat system. To realize this, compact offset fin plate type liquid-to-gas heat exchangers (power densities from 10 to 120 MW/m 3 ) are needed. Both metal and non-metal heat exchangers are being investigated for high-temperature, gas-cooled reactors for temperatures to 1000 deg. C. Recent high temperature heat exchanger studies for nuclear hydrogen production has suggested that carbon-coated composite materials such as liquid silicon infiltrated chopped fiber carbon-carbon preformed material potentially could be used to fabricate plate fin heat exchangers with reasonable price. Different fluids such as helium, nitrogen and helium mixture, and supercritical CO 2 are compared for these multiple reheat Brayton cycles. Nitrogen and helium mixture cycle need about 40% more total PCU volume than helium cycle while keeping the same net cycle efficiency. Supercritical CO 2 needs very high pressure to optimize. Due to relatively detailed design for components such as heat exchangers, turbomachinery, and duct system, relatively accurate total pressure loss can be obtained, which results in more credible net efficiency

  6. IMAGE CAPTURE WITH SYNCHRONIZED MULTIPLE-CAMERAS FOR EXTRACTION OF ACCURATE GEOMETRIES

    Directory of Open Access Journals (Sweden)

    M. Koehl

    2016-06-01

    Full Text Available This paper presents a project of recording and modelling tunnels, traffic circles and roads from multiple sensors. The aim is the representation and the accurate 3D modelling of a selection of road infrastructures as dense point clouds in order to extract profiles and metrics from it. Indeed, these models will be used for the sizing of infrastructures in order to simulate exceptional convoy truck routes. The objective is to extract directly from the point clouds the heights, widths and lengths of bridges and tunnels, the diameter of gyrating and to highlight potential obstacles for a convoy. Light, mobile and fast acquisition approaches based on images and videos from a set of synchronized sensors have been tested in order to obtain useable point clouds. The presented solution is based on a combination of multiple low-cost cameras designed on an on-boarded device allowing dynamic captures. The experimental device containing GoPro Hero4 cameras has been set up and used for tests in static or mobile acquisitions. That way, various configurations have been tested by using multiple synchronized cameras. These configurations are discussed in order to highlight the best operational configuration according to the shape of the acquired objects. As the precise calibration of each sensor and its optics are major factors in the process of creation of accurate dense point clouds, and in order to reach the best quality available from such cameras, the estimation of the internal parameters of fisheye lenses of the cameras has been processed. Reference measures were also realized by using a 3D TLS (Faro Focus 3D to allow the accuracy assessment.

  7. Image Capture with Synchronized Multiple-Cameras for Extraction of Accurate Geometries

    Science.gov (United States)

    Koehl, M.; Delacourt, T.; Boutry, C.

    2016-06-01

    This paper presents a project of recording and modelling tunnels, traffic circles and roads from multiple sensors. The aim is the representation and the accurate 3D modelling of a selection of road infrastructures as dense point clouds in order to extract profiles and metrics from it. Indeed, these models will be used for the sizing of infrastructures in order to simulate exceptional convoy truck routes. The objective is to extract directly from the point clouds the heights, widths and lengths of bridges and tunnels, the diameter of gyrating and to highlight potential obstacles for a convoy. Light, mobile and fast acquisition approaches based on images and videos from a set of synchronized sensors have been tested in order to obtain useable point clouds. The presented solution is based on a combination of multiple low-cost cameras designed on an on-boarded device allowing dynamic captures. The experimental device containing GoPro Hero4 cameras has been set up and used for tests in static or mobile acquisitions. That way, various configurations have been tested by using multiple synchronized cameras. These configurations are discussed in order to highlight the best operational configuration according to the shape of the acquired objects. As the precise calibration of each sensor and its optics are major factors in the process of creation of accurate dense point clouds, and in order to reach the best quality available from such cameras, the estimation of the internal parameters of fisheye lenses of the cameras has been processed. Reference measures were also realized by using a 3D TLS (Faro Focus 3D) to allow the accuracy assessment.

  8. Network Competition - the Coexistence of Hub-and-Spoke and Point-to-Point Systems

    NARCIS (Netherlands)

    Alderighi, M.; Cento, A.; Nijkamp, P.; Rietveld, P.

    2005-01-01

    The paper identifies conditions under which asymmetric equilibria may exist when carriers compete in designing their network configurations in a game-theoretical framework. Two carriers are assumed here, which are allowed to play three different strategies: Point-to-point (PP), hub-and-spoke (HS) or

  9. Design of e-Science platform for biomedical imaging research cross multiple academic institutions and hospitals

    Science.gov (United States)

    Zhang, Jianguo; Zhang, Kai; Yang, Yuanyuan; Ling, Tonghui; Wang, Tusheng; Wang, Mingqing; Hu, Haibo; Xu, Xuemin

    2012-02-01

    More and more image informatics researchers and engineers are considering to re-construct imaging and informatics infrastructure or to build new framework to enable multiple disciplines of medical researchers, clinical physicians and biomedical engineers working together in a secured, efficient, and transparent cooperative environment. In this presentation, we show an outline and our preliminary design work of building an e-Science platform for biomedical imaging and informatics research and application in Shanghai. We will present our consideration and strategy on designing this platform, and preliminary results. We also will discuss some challenges and solutions in building this platform.

  10. Generalized linear models and point count data: statistical considerations for the design and analysis of monitoring studies

    Science.gov (United States)

    Nathaniel E. Seavy; Suhel Quader; John D. Alexander; C. John Ralph

    2005-01-01

    The success of avian monitoring programs to effectively guide management decisions requires that studies be efficiently designed and data be properly analyzed. A complicating factor is that point count surveys often generate data with non-normal distributional properties. In this paper we review methods of dealing with deviations from normal assumptions, and we focus...

  11. Stepped-wedge cluster randomised controlled trials: a generic framework including parallel and multiple-level designs.

    Science.gov (United States)

    Hemming, Karla; Lilford, Richard; Girling, Alan J

    2015-01-30

    Stepped-wedge cluster randomised trials (SW-CRTs) are being used with increasing frequency in health service evaluation. Conventionally, these studies are cross-sectional in design with equally spaced steps, with an equal number of clusters randomised at each step and data collected at each and every step. Here we introduce several variations on this design and consider implications for power. One modification we consider is the incomplete cross-sectional SW-CRT, where the number of clusters varies at each step or where at some steps, for example, implementation or transition periods, data are not collected. We show that the parallel CRT with staggered but balanced randomisation can be considered a special case of the incomplete SW-CRT. As too can the parallel CRT with baseline measures. And we extend these designs to allow for multiple layers of clustering, for example, wards within a hospital. Building on results for complete designs, power and detectable difference are derived using a Wald test and obtaining the variance-covariance matrix of the treatment effect assuming a generalised linear mixed model. These variations are illustrated by several real examples. We recommend that whilst the impact of transition periods on power is likely to be small, where they are a feature of the design they should be incorporated. We also show examples in which the power of a SW-CRT increases as the intra-cluster correlation (ICC) increases and demonstrate that the impact of the ICC is likely to be smaller in a SW-CRT compared with a parallel CRT, especially where there are multiple levels of clustering. Finally, through this unified framework, the efficiency of the SW-CRT and the parallel CRT can be compared. © 2014 The Authors. Statistics in Medicine Published by John Wiley & Sons Ltd.

  12. Barrier potential design criteria in multiple-quantum-well-based solar-cell structures

    Science.gov (United States)

    Mohaidat, Jihad M.; Shum, Kai; Wang, W. B.; Alfano, R. R.

    1994-01-01

    The barrier potential design criteria in multiple-quantum-well (MQW)-based solar-cell structures is reported for the purpose of achieving maximum efficiency. The time-dependent short-circuit current density at the collector side of various MQW solar-cell structures under resonant condition was numerically calculated using the time-dependent Schroedinger equation. The energy efficiency of solar cells based on the InAs/Ga(y)In(1-y)As and GaAs/Al(x)Ga(1-x)As MQW structues were compared when carriers are excited at a particular solar-energy band. Using InAs/Ga(y)In(1-y)As MQW structures it is found that a maximum energy efficiency can be achieved if the structure is designed with barrier potential of about 450 meV. The efficiency is found to decline linearly as the barrier potential increases for GaAs/Al(x)Ga(1-x)As MQW-structure-based solar cells.

  13. Research on reform plan of civil engineering adult education graduation design

    Science.gov (United States)

    Su, Zhibin; Sun, Shengnan; Cui, Shicai

    2017-12-01

    As for civil engineering adult education graduation design, reform program is put forward combined with our school. The main points of reform include the following aspects. New pattern of graduation design which is consisted of basic training of engineering design, technical application and engineering innovation training is formed. Integration model of graduation design and employment is carried out. Multiple professional guidance graduation design pattern is put forward. Subject of graduation design is chosen based on the school actual circumstance. A “three stage” quality monitoring system is established. Performance evaluation pattern that concludes two oral examinations of the dissertation is strictly carried out.

  14. Design, Results, Evolution and Status of the ATLAS Simulation at Point1 Project

    CERN Document Server

    AUTHOR|(SzGeCERN)377840; Fressard-Batraneanu, Silvia Maria; Ballestrero, Sergio; Contescu, Alexandru Cristian; Fazio, Daniel; Di Girolamo, Alessandro; Lee, Christopher Jon; Pozo Astigarraga, Mikel Eukeni; Scannicchio, Diana; Sedov, Alexey; Twomey, Matthew Shaun; Wang, Fuquan; Zaytsev, Alexander

    2015-01-01

    Abstract. During the LHC Long Shutdown 1 period (LS1), that started in 2013, the Simulation at Point1 (Sim@P1) Project takes advantage, in an opportunistic way, of the TDAQ (Trigger and Data Acquisition) HLT (High Level Trigger) farm of the ATLAS experiment. This farm provides more than 1300 compute nodes, which are particularly suited for running event generation and Monte Carlo production jobs that are mostly CPU and not I/O bound. It is capable of running up to 2700 virtual machines (VMs) provided with 8 CPU cores each, for a total of up to 22000 parallel running jobs. This contribution gives a review of the design, the results, and the evolution of the Sim@P1 Project; operating a large scale OpenStack based virtualized platform deployed on top of the ATLAS TDAQ HLT farm computing resources. During LS1, Sim@P1 was one of the most productive ATLAS sites: it delivered more than 50 million CPU-hours and it generated more than 1.7 billion Monte Carlo events to various analysis communities. The design aspects a...

  15. Design, Results, Evolution and Status of the ATLAS simulation in Point1 project.

    CERN Document Server

    Ballestrero, Sergio; The ATLAS collaboration; Brasolin, Franco; Contescu, Alexandru Cristian; Fazio, Daniel; Di Girolamo, Alessandro; Lee, Christopher Jon; Pozo Astigarraga, Mikel Eukeni; Scannicchio, Diana; Sedov, Alexey; Twomey, Matthew Shaun; Wang, Fuquan; Zaytsev, Alexander

    2015-01-01

    During the LHC long shutdown period (LS1), that started in 2013, the simulation in Point1 (Sim@P1) project takes advantage in an opportunistic way of the trigger and data acquisition (TDAQ) farm of the ATLAS experiment. The farm provides more than 1500 computer nodes, and they are particularly suitable for running event generation and Monte Carlo production jobs that are mostly CPU and not I/O bound. It is capable of running up to 2500 virtual machines (VM) provided with 8 CPU cores each, for a total of up to 20000 parallel running jobs. This contribution gives a thorough review of the design, the results and the evolution of the Sim@P1 project operating a large scale Openstack based virtualized platform deployed on top of the ATLAS TDAQ farm computing resources. During LS1, Sim@P1 was one of the most productive GRID sites: it delivered more than 50 million CPU-hours and it generated more than 1.7 billion Monte Carlo events to various analysis communities within the ATLAS collaboration. The particular design ...

  16. An unusual pattern of tattooing in the form of body designing: A case report

    Directory of Open Access Journals (Sweden)

    Laxman Gangadhar Phad

    2016-12-01

    In the present case the patient was brought to our hospital for eliciting consumption of alcohol and any other injuries over the body. The person examined had decorated his left arm and forearm by fine designs by a blue ball point pen. He also had multiple fresh incised cuts on the forearms and wrist. Such a presentation with a somewhat risk taking, masochistic behavior and the chronic nature of drawing designs over the body by a ball point pen was very rare and not noted as per best of our knowledge.

  17. Sequential Multiple Assignment Randomized Trials: An Opportunity for Improved Design of Stroke Reperfusion Trials.

    Science.gov (United States)

    Meurer, William J; Seewald, Nicholas J; Kidwell, Kelley

    2017-04-01

    Modern clinical trials in stroke reperfusion fall into 2 categories: alternative systemic pharmacological regimens to alteplase and "rescue" endovascular approaches using targeted thrombectomy devices and/or medications delivered directly for persistently occluded vessels. Clinical trials in stroke have not evaluated how initial pharmacological thrombolytic management might influence subsequent rescue strategy. A sequential multiple assignment randomized trial (SMART) is a novel trial design that can test these dynamic treatment regimens and lead to treatment guidelines that more closely mimic practice. To characterize a SMART design in comparison to traditional approaches for stroke reperfusion trials. We conducted a numerical simulation study that evaluated the performance of contrasting acute stroke clinical trial designs of both initial reperfusion and rescue therapy. We compare a SMART design where the same patients are followed through initial reperfusion and rescue therapy within 1 trial to a standard phase III design comparing 2 reperfusion treatments and a separate phase II futility design of rescue therapy in terms of sample size, power, and ability to address particular research questions. Traditional trial designs can be well powered and have optimal design characteristics for independent treatment effects. When treatments, such as the reperfusion and rescue therapies, may interact, commonly used designs fail to detect this. A SMART design, with similar sample size to standard designs, can detect treatment interactions. The use of SMART designs to investigate effective and realistic dynamic treatment regimens is a promising way to accelerate the discovery of new, effective treatments for stroke. Copyright © 2017 National Stroke Association. Published by Elsevier Inc. All rights reserved.

  18. Rise to SUMMIT: the Sydney University Multiple-Mirror Telescope

    Science.gov (United States)

    Moore, Anna M.; Davis, John

    2000-07-01

    The Sydney University Multiple Mirror Telescope (SUMMIT) is a medium-sized telescope designed specifically for high resolution stellar spectroscopy. Throughout the design emphasis has been placed on high efficiency at low cost. The telescope consists of four 0.46 m diameter mirrors mounted on a single welded steel frame. Specially designed mirror cells support and point each mirror, allowing accurate positioning of the images on optical fibers located at the foci of the mirrors. Four fibers convey the light to the future location of a high resolution spectrograph away from the telescope in a stable environment. An overview of the commissioning of the telescope is presented, including the guidance and automatic mirror alignment and focussing systems. SUMMIT is located alongside the Sydney University Stellar Interferometer at the Paul Wild Observatory, near Narrabri, Northern New South Wales.

  19. Digital microwave communication engineering point-to-point microwave systems

    CERN Document Server

    Kizer, George

    2013-01-01

    The first book to cover all engineering aspects of microwave communication path design for the digital age Fixed point-to-point microwave systems provide moderate-capacity digital transmission between well-defined locations. Most popular in situations where fiber optics or satellite communication is impractical, it is commonly used for cellular or PCS site interconnectivity where digital connectivity is needed but not economically available from other sources, and in private networks where reliability is most important. Until now, no book has adequately treated all en

  20. Unbounded critical points for a class of lower semicontinuous functionals

    OpenAIRE

    Pellacci, Benedetta; Squassina, Marco

    2003-01-01

    In this paper we prove existence and multiplicity results of unbounded critical points for a general class of weakly lower semicontinuous functionals. We will apply a suitable nonsmooth critical point theory.

  1. Key points for the design of Mox facilities

    International Nuclear Information System (INIS)

    Ducroux, R.; Gaiffe, L.; Dumond, S.; Cret, L.

    1998-01-01

    The design of a MOX fuel fabrication facility involves specific technical difficulties: - Process aspects: for example, its is necessary to meet the stringent requirements on the end products, while handling large quantities of powders and pellets; - Safety aspects: for example, containment of radioactive materials requires to use gloveboxes, to design process equipment so as to limit dispersion to the gloveboxes and to use systems for dust collection. - Technological aspects: for example, it is necessary to take into account maintenance early in the design, in order to lower the operation costs and lower the dose to the personnel. - Quality control and information systems: for example, it is necessary to be able to trace all the different products (powder lots, pellets, rods, assemblies). The design methods and organization set-up by COGEMA enables to master these technical difficulties during the different design steps and to obtain a MOX fabrication facility at the best performance versus cost compromise. These design methods rely mainly on: - taking into account all the different above mentioned constraints from the very beginning of the design process (by using the know-how resulting from experience feed-back, and also specific design tools developed by COGEMA and SGN); - launching a technical development and testing program at the beginning of the project and incorporating its results in the course of the design. (author)

  2. Design of the control system for fixed-point keeping in FPSO (Floating Production Storage and Offloading); FPSO no teiten hoji no tame no seigyokei no sekkei ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    Kijima, K; Murata, W; Furukawa, Y [Kyushu University, Fukuoka (Japan). Faculty of Engineering

    1997-10-01

    The control system for keeping the fixed-point of ships against disturbance was designed by applying an ILQ (Inverse Linear Quadratic) control (possible to specify the response of controlled systems with time constant) theory, to study the effect of different time constants as design parameter on a fixed-point keeping performance. It was assumed that the controlled ship is equipped with two bow thrusters and one stern thruster of 30ton in output to generate a control force. For fixed-point keeping control, the state equation was derived to slave the controlled system to a target input. The ILQ design method uses the result of the inverse problem of optimum regulators. For designing control systems by using the ILQ control theory, the smallest time constant should be selected according to the most severe disturbance condition considering the response performance of controllers, to achieve fixed-point keeping of ships. In fixed-point keeping, it is also essential to put the initial position as close as possible to the target point. 2 refs., 6 figs., 2 tabs.

  3. Design and Implementation of Numerical Linear Algebra Algorithms on Fixed Point DSPs

    Directory of Open Access Journals (Sweden)

    Gene Frantz

    2007-01-01

    Full Text Available Numerical linear algebra algorithms use the inherent elegance of matrix formulations and are usually implemented using C/C++ floating point representation. The system implementation is faced with practical constraints because these algorithms usually need to run in real time on fixed point digital signal processors (DSPs to reduce total hardware costs. Converting the simulation model to fixed point arithmetic and then porting it to a target DSP device is a difficult and time-consuming process. In this paper, we analyze the conversion process. We transformed selected linear algebra algorithms from floating point to fixed point arithmetic, and compared real-time requirements and performance between the fixed point DSP and floating point DSP algorithm implementations. We also introduce an advanced code optimization and an implementation by DSP-specific, fixed point C code generation. By using the techniques described in the paper, speed can be increased by a factor of up to 10 compared to floating point emulation on fixed point hardware.

  4. Employing optical code division multiple access technology in the all fiber loop vibration sensor system

    Science.gov (United States)

    Tseng, Shin-Pin; Yen, Chih-Ta; Syu, Rong-Shun; Cheng, Hsu-Chih

    2013-12-01

    This study proposes a spectral amplitude coding-optical code division multiple access (SAC-OCDMA) framework to access the vibration frequency of a test object on the all fiber loop vibration sensor (AFLVS). Each user possesses an individual SAC, and fiber Bragg grating (FBG) encoders/decoders using multiple FBG arrays were adopted, providing excellent orthogonal properties in the frequency domain. The system also mitigates multiple access interference (MAI) among users. When an optical fiber is bent to a point exceeding the critical radius, the fiber loop sensor becomes sensitive to external physical parameters (e.g., temperature, strain, and vibration). The AFLVS involves placing a fiber loop with a specific radius on a designed vibration platform.

  5. Design and implementation of the reconstruction software for the photon multiplicity detector in object oriented programming framework

    International Nuclear Information System (INIS)

    Chattopadhayay, Subhasis; Ghosh, Premomoy; Gupta, R.; Mishra, D.; Phatak, S.C.; Sood, G.

    2002-01-01

    High granularity photon multiplicity detector (PMD) is scheduled to take data in Relativistic Heavy Ion Collision(RHIC) this year. A detailed scheme has been designed and implemented in object oriented programming framework using C++ for the monitoring and reconstruction job of PMD data

  6. Novel anti-HIV peptides containing multiple copies of artificially designed heptad repeat motifs

    International Nuclear Information System (INIS)

    Shi Weiguo; Qi Zhi; Pan Chungen; Xue Na; Debnath, Asim K.; Qie Jiankun; Jiang Shibo; Liu Keliang

    2008-01-01

    The peptidic anti-HIV drug T20 (Fuzeon) and its analog C34 share a common heptad repeat (HR) sequence, but they have different functional domains, i.e., pocket- and lipid-binding domains (PBD and LBD, respectively). We hypothesize that novel anti-HIV peptides may be designed by using artificial sequences containing multiple copies of HR motifs plus zero, one or two functional domains. Surprisingly, we found that the peptides containing only the non-natural HR sequences could significantly inhibit HIV-1 infection, while addition of PBD and/or LBD to the peptides resulted in significant improvement of anti-HIV-1 activity. These results suggest that these artificial HR sequences, which may serve as structural domains, could be used as templates for the design of novel antiviral peptides against HIV and other viruses with class I fusion proteins

  7. Design of four-point SENB specimens with stable crack growth

    DEFF Research Database (Denmark)

    Jørgensen, Jeppe Bjørn; Kildegaard, Casper; Sørensen, Bent F.

    2018-01-01

    A four-point single-edge-notch-beam (SENB) test specimen loaded in displacement control (fixed grip) is proposed for studying crack deflection at bi-material interfaces. In order to ensure stable crack growth, a novel analytical model of the four-point SENB specimen in fixed grip is derived...... and compared with numerical models. Model results show that the specimen should be short and thick, and the start-crack length should be deep for the crack to propagate stable towards the bi-material interface. Observations from experimental tests of four-point SENB specimens with different start-crack lengths...

  8. Staging Mobilities / Designing Mobilities

    DEFF Research Database (Denmark)

    Jensen, Ole B.

    2015-01-01

    , and systems 'hosting' these multiple and complex mobilities are designed and how they are staging these in terms of their physical layout. By analysing specific cases of ‘mobilities design’ related to the four modes of moving; Walk, Bike, Train, and Car, the book uncover important and until now neglected...... is more than movement between point A and B. It explores how the movement of people, goods, information, and signs influences human understandings of self, other and the built environment. Moving towards a new understanding of the relationship between movement, interaction and environments, the project...

  9. Tuning the color point of a white LED

    NARCIS (Netherlands)

    Adhikary, Manashee; Meretska, Maryna; Ladovrechis, K.; Fokkema, Wouter K.; Vissenberg, Gilles; Lagendijk, Ad; Ijzerman, W.L.; Vos, Willem L.

    2018-01-01

    White light is conveniently characterized by a color point that is represented on the color space. Color point of white LED is fixed by the design parameters (e.g. Phosphor type and concentration). When the design parameters are chosen, the color point of the white LED cannot be changed. Here, we

  10. A SCHEDULING SCHEME WITH DYNAMIC FREQUENCY CLOCKING AND MULTIPLE VOLTAGES FOR LOW POWER DESIGNS

    Institute of Scientific and Technical Information of China (English)

    Wen Dongxin; Wang Ling; Yang Xiaozong

    2007-01-01

    In this letter, a scheduling scheme based on Dynamic Frequency Clocking (DFC) and multiple voltages is proposed for low power designs under the timing and the resource constraints.Unlike the conventional methods at high level synthesis where only voltages of nodes were considered,the scheme based on a gain function considers both voltage and frequency simultaneously to reduce energy consumption. Experiments with a number of DSP benchmarks show that the proposed scheme achieves an effective energy reduction.

  11. Optimal design of hydraulic excavator working device based on multiple surrogate models

    Directory of Open Access Journals (Sweden)

    Qingying Qiu

    2016-05-01

    Full Text Available The optimal design of hydraulic excavator working device is often characterized by computationally expensive analysis methods such as finite element analysis. Significant difficulties also exist when using a sensitivity-based decomposition approach to such practical engineering problems because explicit mathematical formulas between the objective function and design variables are impossible to formulate. An effective alternative is known as the surrogate model. The purpose of this article is to provide a comparative study on multiple surrogate models, including the response surface methodology, Kriging, radial basis function, and support vector machine, and select the one that best fits the optimization of the working device. In this article, a new modeling strategy based on the combination of the dimension variables between hinge joints and the forces loaded on hinge joints of the working device is proposed. In addition, the extent to which the accuracy of the surrogate models depends on different design variables is presented. The bionic intelligent optimization algorithm is then used to obtain the optimal results, which demonstrate that the maximum stresses calculated by the predicted method and finite element analysis are quite similar, but the efficiency of the former is much higher than that of the latter.

  12. Multiples waveform inversion

    KAUST Repository

    Zhang, Dongliang

    2013-01-01

    To increase the illumination of the subsurface and to eliminate the dependency of FWI on the source wavelet, we propose multiples waveform inversion (MWI) that transforms each hydrophone into a virtual point source with a time history equal to that of the recorded data. These virtual sources are used to numerically generate downgoing wavefields that are correlated with the backprojected surface-related multiples to give the migration image. Since the recorded data are treated as the virtual sources, knowledge of the source wavelet is not required, and the subsurface illumination is greatly enhanced because the entire free surface acts as an extended source compared to the radiation pattern of a traditional point source. Numerical tests on the Marmousi2 model show that the convergence rate and the spatial resolution of MWI is, respectively, faster and more accurate then FWI. The potential pitfall with this method is that the multiples undergo more than one roundtrip to the surface, which increases attenuation and reduces spatial resolution. This can lead to less resolved tomograms compared to conventional FWI. The possible solution is to combine both FWI and MWI in inverting for the subsurface velocity distribution.

  13. A multiplicity logic unit

    International Nuclear Information System (INIS)

    Bialkowski, J.; Moszynski, M.; Zagorski, A.

    1981-01-01

    The logic diagram principle of operation and some details of the design of the multiplicity logic unit are presented. This unit was specially designed to fulfil the requirements of a multidetector arrangement for gamma-ray multiplicity measurements. The unit is equipped with 16 inputs controlled by a common coincidence gate. It delivers a linear output pulse with the height proportional to the multiplicity of coincidences and logic pulses corresponding to 0, 1, ... up to >= 5-fold coincidences. These last outputs are used to steer the routing unit working with the multichannel analyser. (orig.)

  14. Point-of-care testing: applications of 3D printing.

    Science.gov (United States)

    Chan, Ho Nam; Tan, Ming Jun Andrew; Wu, Hongkai

    2017-08-08

    Point-of-care testing (POCT) devices fulfil a critical need in the modern healthcare ecosystem, enabling the decentralized delivery of imperative clinical strategies in both developed and developing worlds. To achieve diagnostic utility and clinical impact, POCT technologies are immensely dependent on effective translation from academic laboratories out to real-world deployment. However, the current research and development pipeline is highly bottlenecked owing to multiple restraints in material, cost, and complexity of conventionally available fabrication techniques. Recently, 3D printing technology has emerged as a revolutionary, industry-compatible method enabling cost-effective, facile, and rapid manufacturing of objects. This has allowed iterative design-build-test cycles of various things, from microfluidic chips to smartphone interfaces, that are geared towards point-of-care applications. In this review, we focus on highlighting recent works that exploit 3D printing in developing POCT devices, underscoring its utility in all analytical steps. Moreover, we also discuss key advantages of adopting 3D printing in the device development pipeline and identify promising opportunities in 3D printing technology that can benefit global health applications.

  15. Multiple x-ray diffraction simulation and applications

    International Nuclear Information System (INIS)

    Costa, C.A.B.S. da.

    1989-09-01

    A computer program (MULTX) was implemented for simulation X-ray multiple diffraction diagrams in Renninger geometries. The program uses the X-ray multiple diffraction theory for imperfect crystals. The iterative calculation of the intensities is based on the Taylor series general term, and the primary beam power expansion is given as function of the beam x penetration in the crystal surface. This development allows to consider the simultaneous interaction of the beams involved in the multiple diffraction phenomenon. The simulated diagrams are calculated point-to-point and the tests for the Si and GaAs presented good reproduction of the experimental diagrams for different primary reflections. (L.C.J.A.)

  16. Optimization of the NIF ignition point design hohlraum

    International Nuclear Information System (INIS)

    Callahan, D A; Hinkel, D E; Berger, R L; Divol, L; Dixit, S N; Edwards, M J; Haan, S W; Jones, O S; Lindl, J D; Meezan, N B; Michel, P A; Pollaine, S M; Suter, L J; Town, R P J; Bradley, P A

    2008-01-01

    In preparation for the start of NIF ignition experiments, we have designed a porfolio of targets that span the temperature range that is consistent with initial NIF operations: 300 eV, 285 eV, and 270 eV. Because these targets are quite complicated, we have developed a plan for choosing the optimum hohlraum for the first ignition attempt that is based on this portfolio of designs coupled with early NIF experiements using 96 beams. These early experiments will measure the laser plasma instabilities of the candidate designs and will demonstrate our ability to tune symmetry in these designs. These experimental results, coupled with the theory and simulations that went into the designs, will allow us to choose the optimal hohlraum for the first NIF ignition attempt

  17. Optimization of the NIF ignition point design hohlraum

    Science.gov (United States)

    Callahan, D. A.; Hinkel, D. E.; Berger, R. L.; Divol, L.; Dixit, S. N.; Edwards, M. J.; Haan, S. W.; Jones, O. S.; Lindl, J. D.; Meezan, N. B.; Michel, P. A.; Pollaine, S. M.; Suter, L. J.; Town, R. P. J.; Bradley, P. A.

    2008-05-01

    In preparation for the start of NIF ignition experiments, we have designed a porfolio of targets that span the temperature range that is consistent with initial NIF operations: 300 eV, 285 eV, and 270 eV. Because these targets are quite complicated, we have developed a plan for choosing the optimum hohlraum for the first ignition attempt that is based on this portfolio of designs coupled with early NIF experiements using 96 beams. These early experiments will measure the laser plasma instabilities of the candidate designs and will demonstrate our ability to tune symmetry in these designs. These experimental results, coupled with the theory and simulations that went into the designs, will allow us to choose the optimal hohlraum for the first NIF ignition attempt.

  18. Analyses for designing objects in mechanical design

    International Nuclear Information System (INIS)

    Nakajima, Norihiro; Miyamura, Hiroko N.; Kawakami, Yoshiaki; Kawamura, Takuma

    2015-01-01

    Defining factors to induce the damage that can be assumed in the mechanical structures, it is a loaded work to analyze a damage possibility point derived by the assumption phenomenon that can occur is, but it is the important designing process. Taking factors caused by the earthquake as an example, and simulating the phenomenon that can be assumed, the computational result was analyzed with information visualization. A damage possibility point by analyzing the result mathematically. The illustration of analytical results may give points to designers as means for a designer to recognize a damage possibility point from the sensitivity of the designer. (author)

  19. Pro SharePoint 2013 administration

    CERN Document Server

    Garrett, Robert

    2013-01-01

    Pro SharePoint 2013 Administration is a practical guide to SharePoint 2013 for intermediate to advanced SharePoint administrators and power users, covering the out-of-the-box feature set and capabilities of Microsoft's collaboration and business productivity platform. SharePoint 2013 is an incredibly complex product, with many moving parts, new features, best practices, and 'gotchas.' Author Rob Garrett distills SharePoint's portfolio of features, capabilities, and utilities into an in-depth professional guide-with no fluff and copious advice-that is designed from scratch to be the manual Micr

  20. On the Performance of the Measure for Diagnosing Multiple High Leverage Collinearity-Reducing Observations

    Directory of Open Access Journals (Sweden)

    Arezoo Bagheri

    2012-01-01

    Full Text Available There is strong evidence indicating that the existing measures which are designed to detect a single high leverage collinearity-reducing observation are not effective in the presence of multiple high leverage collinearity-reducing observations. In this paper, we propose a cutoff point for a newly developed high leverage collinearity-influential measure and two existing measures ( and to identify high leverage collinearity-reducing observations, the high leverage points which hide multicollinearity in a data set. It is important to detect these observations as they are responsible for the misleading inferences about the fitting of the regression model. The merit of our proposed measure and cutoff point in detecting high leverage collinearity-reducing observations is investigated by using engineering data and Monte Carlo simulations.

  1. When should we recommend use of dual time-point and delayed time-point imaging techniques in FDG PET?

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Gang [Philadelphia VA Medical Center, Department of Radiology, Philadelphia, PA (United States); Hospital of the University of Pennsylvania, Department of Radiology, Philadelphia, PA (United States); Torigian, Drew A.; Alavi, Abass [Hospital of the University of Pennsylvania, Department of Radiology, Philadelphia, PA (United States); Zhuang, Hongming [Children' s Hospital of Philadelphia, Department of Radiology, Philadelphia, PA (United States)

    2013-05-15

    FDG PET and PET/CT are now widely used in oncological imaging for tumor characterization, staging, restaging, and response evaluation. However, numerous benign etiologies may cause increased FDG uptake indistinguishable from that of malignancy. Multiple studies have shown that dual time-point imaging (DTPI) of FDG PET may be helpful in differentiating malignancy from benign processes. However, exceptions exist, and some studies have demonstrated significant overlap of FDG uptake patterns between benign and malignant lesions on delayed time-point images. In this review, we summarize our experience and opinions on the value of DTPI and delayed time-point imaging in oncology, with a review of the relevant literature. We believe that the major value of DTPI and delayed time-point imaging is the increased sensitivity due to continued clearance of background activity and continued FDG accumulation in malignant lesions, if the same diagnostic criteria (as in the initial standard single time-point imaging) are used. The specificity of DTPI and delayed time-point imaging depends on multiple factors, including the prevalence of malignancies, the patient population, and the cut-off values (either SUV or retention index) used to define a malignancy. Thus, DTPI and delayed time-point imaging would be more useful if performed for evaluation of lesions in regions with significant background activity clearance over time (such as the liver, the spleen, the mediastinum), and if used in the evaluation of the extent of tumor involvement rather than in the characterization of the nature of any specific lesion. Acute infectious and non-infectious inflammatory lesions remain as the major culprit for diminished diagnostic performance of these approaches (especially in tuberculosis-endemic regions). Tumor heterogeneity may also contribute to inconsistent performance of DTPI. The authors believe that selective use of DTPI and delayed time-point imaging will improve diagnostic accuracy and

  2. Poisson point processes imaging, tracking, and sensing

    CERN Document Server

    Streit, Roy L

    2010-01-01

    This overview of non-homogeneous and multidimensional Poisson point processes and their applications features mathematical tools and applications from emission- and transmission-computed tomography to multiple target tracking and distributed sensor detection.

  3. Design of Farthest-Point Masks for Image Halftoning

    Directory of Open Access Journals (Sweden)

    Ramponi G

    2004-01-01

    Full Text Available In an earlier paper, we briefly presented a new halftoning algorithm called farthest-point halftoning. In the present paper, this method is analyzed in detail, and a novel dispersion measure is defined to improve the simplicity and flexibility of the result. This new stochastic screen algorithm is loosely based on Kang's dispersed-dot ordered dither halftone array construction technique used as part of his microcluster halftoning method. Our new halftoning algorithm uses pixelwise measures of dispersion based on one proposed by Kang which is here modified to be more effective. In addition, our method exploits the concept of farthest-point sampling (FPS, introduced as a progressive irregular sampling method by Eldar et al. but uses a more efficient implementation of FPS in the construction of the dot profiles. The technique we propose is compared to other state-of-the-art dither-based halftoning methods in both qualitative and quantitative manners.

  4. Performance of Cross-layer Design with Multiple Outdated Estimates in Multiuser MIMO System

    Directory of Open Access Journals (Sweden)

    X. Yu

    2014-09-01

    Full Text Available By combining adaptive modulation (AM and automatic repeat request (ARQ protocol as well as user scheduling, the cross-layer design scheme of multiuser MIMO system with imperfect feedback is presented, and multiple outdated estimates method is proposed to improve the system performance. Based on this method and imperfect feedback information, the closed-form expressions of spectral efficiency (SE and packet error rate (PER of the system subject to the target PER constraint are respectively derived. With these expressions, the system performance can be effectively evaluated. To mitigate the effect of delayed feedback, the variable thresholds (VTs are also derived by means of the maximum a posteriori method, and these VTs include the conventional fixed thresholds (FTs as special cases. Simulation results show that the theoretical SE and PER are in good agreement with the corresponding simulation. The proposed CLD scheme with multiple estimates can obtain higher SE than the existing CLD scheme with single estimate, especially for large delay. Moreover, the CLD scheme with VTs outperforms that with conventional FTs.

  5. Combining different types of scale space interest points using canonical sets

    NARCIS (Netherlands)

    Kanters, F.M.W.; Denton, T.; Shokoufandeh, A.; Florack, L.M.J.; Haar Romenij, ter B.M.; Sgallari, F.; Murli, A.; Paragios, N.

    2007-01-01

    Scale space interest points capture important photometric and deep structure information of an image. The information content of such points can be made explicit using image reconstruction. In this paper we will consider the problem of combining multiple types of interest points used for image

  6. Base Isolation for Seismic Retrofitting of a Multiple Building Structure: Design, Construction, and Assessment

    Directory of Open Access Journals (Sweden)

    Massimiliano Ferraioli

    2017-01-01

    Full Text Available The paper deals with the seismic retrofit of a multiple building structure belonging to the Hospital Centre of Avellino (Italy. At first, the paper presents the preliminary investigations, the in situ measurements and laboratory tests, and the seismic assessment of the existing fixed-base structures. Having studied different strategies, base isolation proved to be the more appropriate, also for the possibility offered by the geometry of the building to easily create an isolation interface at the ground level. The paper presents the design project, the construction process, and the details of the isolation intervention. Some specific issues of base isolation for seismic retrofitting of multiple building structures were lightened. Finally, the seismic assessment of the base-isolated building was carried out. The seismic response was evaluated through nonlinear time-history analysis, using the well-known Bouc-Wen model as the constitutive law of the isolation bearings. For reliable dynamic analyses, a suite of natural accelerograms compatible with acceleration spectra of Italian Code was first selected and then applied along both horizontal directions. The results were finally used to address some of the critical issues of the seismic response of the base-isolated multiple building structure: accidental torsional effects and potential poundings during strong earthquakes.

  7. Non-Orthogonal Multiple Access for Large-Scale 5G Networks: Interference Aware Design

    KAUST Repository

    Ali, Konpal S.

    2017-09-18

    Non-orthogonal multiple access (NOMA) is promoted as a key component of 5G cellular networks. As the name implies, NOMA operation introduces intracell interference (i.e., interference arising within the cell) to the cellular operation. The intracell interference is managed by careful NOMA design (e.g., user clustering and resource allocation) along with successive interference cancellation. However, most of the proposed NOMA designs are agnostic to intercell interference (i.e., interference from outside the cell), which is a major performance limiting parameter in 5G networks. This article sheds light on the drastic negative-impact of intercell interference on the NOMA performance and advocates interference-aware NOMA design that jointly accounts for both intracell and intercell interference. To this end, a case study for fair NOMA operation is presented and intercell interference mitigation techniques for NOMA networks are discussed. This article also investigates the potential of integrating NOMA with two important 5G transmission schemes, namely, full duplex and device-to-device communication. This is important since the ambitious performance defined by the 3rd Generation Partnership Project (3GPP) for 5G is foreseen to be realized via seamless integration of several new technologies and transmission techniques.

  8. Pointright: a system to redirect mouse and keyboard control among multiple machines

    Science.gov (United States)

    Johanson, Bradley E [Palo Alto, CA; Winograd, Terry A [Stanford, CA; Hutchins, Gregory M [Mountain View, CA

    2008-09-30

    The present invention provides a software system, PointRight, that allows for smooth and effortless control of pointing and input devices among multiple displays. With PointRight, a single free-floating mouse and keyboard can be used to control multiple screens. When the cursor reaches the edge of a screen it seamlessly moves to the adjacent screen and keyboard control is simultaneously redirected to the appropriate machine. Laptops may also redirect their keyboard and pointing device, and multiple pointers are supported simultaneously. The system automatically reconfigures itself as displays go on, go off, or change the machine they display.

  9. Design point selection for an ignited ITER

    International Nuclear Information System (INIS)

    Spears, W.R.; Mizoguchi, T.; Perkins, J.; Putvinskij, S.; Flanagan, C.

    1989-01-01

    The parameter choice for the ITER design is dominated by the need to achieve ignition. Different energy confinement time scalings extrapolate to different device parameters, and the final design chosen must have a reasonable chance of success under the presently favoured scalings. This study investigates the device performance over the plasma current - aspect ratio design space, using sets of simplified equations and more detailed parametric analysis codes, with a view to clarifying the acceptable parameter region. Alterations to the initial assumptions of plasma elongation, plasma safety factor and peak toroidal field, and the effect of limiting the wall load, are also investigated. The study concludes that a device with aspect ratio around 3 and plasma current about 20 MA would be an appropriate choice. Under the assumptions of the study such a device would have a major radius of about 5.8m and would require the attainment of enhancement factors around 1.5 over L-mode scaling. (author). 6 refs, 11 figs, 3 tabs

  10. "Delineamento duplo central composto com 29 pontos" Double central composite design with 29 points

    Directory of Open Access Journals (Sweden)

    Armando Conagin

    1979-01-01

    Full Text Available O delineamento duplo central composto com 29 pontos representa uma extensão do delineamento central composto e foi desenvolvido para o estudo de três fatores em mais de três níveis. Essencialmente, consta de dois fatoriais 2³ (níveis 1 e B, de duas estrelas (níveis a e 2alfa e de um ponto no centro do delineamento. É mostrada a origem do delineamento, o tipo não ortogonal, completamente casualizado, o tipo ortogonal completamente casualizado e o ortogonal divisível em dois blocos. No primeiro deles, seriam estudados três fatores em cinco níveis (-2, -1,-0, + 1 e +2; no segundo, três fatores em nove níveis (-3,02; -2,00; -1,51; -1,00; 0,00; + 1,00; +1,51; +2,00 e +3.02 e, no terceiro, três fatores nos nove níveis seguintes (-7,262; -4,391; -3,631; -1,000; 0,000; +1,000; +3,631; +4,391 e +7,262. É apresentado também um exemplo do último delineamento. com sua análise respectiva. De acordo com o critério de Box & Wilson (2, esse último delineamento é mais eficiente que o fatorial 3 x 3 x 3 divisível em blocos de nove. Os três delineamentos podem ser empregados em programas de adubação visando ao estudo de macronutrientes com vistas à recomendação das doses ótimas de fertilizantes que possibilitem a maximização do lucro obtido e, ainda, em outras áreas da pesquisa científica em que se deseja a avaliação da superfície de resposta, o estudo dos seus pontos extremos, etc.The double central composite design with 29 points rcpresents an extension of the central composite design and was developed for the study of three factors in more than three levels. Essentially it is composed of two 2³ factorials (levels 1 and B, of two stars (levels alpha and 2alpha and of one central point. In the present paper the origin of the design, the double central composite completely randomized not orthogonal in 5 levels (-2, -1, 0, +1 and +2, the completely randomized design, orthogonal, in nine levels (-3.02; -2.00; -1.51; -1.00; 0

  11. Pro SharePoint 2010 Search

    CERN Document Server

    Noble, J; Bakman-Mikalski, Dan

    2011-01-01

    Pro SharePoint 2010 Search gives you expert advice on planning, deploying and customizing searches in SharePoint 2010. Drawing on the authors' extensive experience of working with real-world SharePoint deployments, this book teaches everything you'll need to know to create well-designed SharePoint solutions that always keep the end-user's experience in mind. Increase your search efficiency with SharePoint 2010's search functionality: extend the search user interface using third-party tools, and utilize analytics to improve relevancy. This practical hands-on book is a must-have resource for any

  12. The design of visible system for improving the measurement accuracy of imaging points

    Science.gov (United States)

    Shan, Qiu-sha; Li, Gang; Zeng, Luan; Liu, Kai; Yan, Pei-pei; Duan, Jing; Jiang, Kai

    2018-02-01

    It has a widely applications in robot vision and 3D measurement for binocular stereoscopic measurement technology. And the measure precision is an very important factor, especially in 3D coordination measurement, high measurement accuracy is more stringent to the distortion of the optical system. In order to improving the measurement accuracy of imaging points, to reducing the distortion of the imaging points, the optical system must be satisfied the requirement of extra low distortion value less than 0.1#65285;, a transmission visible optical lens was design, which has characteristic of telecentric beam path in image space, adopted the imaging model of binocular stereo vision, and imaged the drone at the finity distance. The optical system was adopted complex double Gauss structure, and put the pupil stop on the focal plane of the latter groups, maked the system exit pupil on the infinity distance, and realized telecentric beam path in image space. The system mainly optical parameter as follows: the system spectrum rangement is visible light wave band, the optical effective length is f '=30mm, the relative aperture is 1/3, and the fields of view is 21°. The final design results show that the RMS value of the spread spots of the optical lens in the maximum fields of view is 2.3μm, which is less than one pixel(3.45μm) the distortion value is less than 0.1%, the system has the advantage of extra low distortion value and avoids the latter image distortion correction; the proposed modulation transfer function of the optical lens is 0.58(@145 lp/mm), the imaging quality of the system is closed to the diffraction limited; the system has simply structure, and can satisfies the requirements of the optical indexes. Ultimately, based on the imaging model of binocular stereo vision was achieved to measuring the drone at the finity distance.

  13. The goal of ape pointing.

    Science.gov (United States)

    Halina, Marta; Liebal, Katja; Tomasello, Michael

    2018-01-01

    Captive great apes regularly use pointing gestures in their interactions with humans. However, the precise function of this gesture is unknown. One possibility is that apes use pointing primarily to direct attention (as in "please look at that"); another is that they point mainly as an action request (such as "can you give that to me?"). We investigated these two possibilities here by examining how the looking behavior of recipients affects pointing in chimpanzees (Pan troglodytes) and bonobos (Pan paniscus). Upon pointing to food, subjects were faced with a recipient who either looked at the indicated object (successful-look) or failed to look at the indicated object (failed-look). We predicted that, if apes point primarily to direct attention, subjects would spend more time pointing in the failed-look condition because the goal of their gesture had not been met. Alternatively, we expected that, if apes point primarily to request an object, subjects would not differ in their pointing behavior between the successful-look and failed-look conditions because these conditions differed only in the looking behavior of the recipient. We found that subjects did differ in their pointing behavior across the successful-look and failed-look conditions, but contrary to our prediction subjects spent more time pointing in the successful-look condition. These results suggest that apes are sensitive to the attentional states of gestural recipients, but their adjustments are aimed at multiple goals. We also found a greater number of individuals with a strong right-hand than left-hand preference for pointing.

  14. How PowerPoint Is Killing Education

    Science.gov (United States)

    Isseks, Marc

    2011-01-01

    Although it is essential to incorporate new technologies into the classroom, says Isseks, one trend has negatively affected instruction--the misuse of PowerPoint presentations. The author describes how poorly designed PowerPoint presentations reduce complex thoughts to bullet points and reduce the act of learning to transferring text from slide to…

  15. Utilizing the Double-Precision Floating-Point Computing Power of GPUs for RSA Acceleration

    Directory of Open Access Journals (Sweden)

    Jiankuo Dong

    2017-01-01

    Full Text Available Asymmetric cryptographic algorithm (e.g., RSA and Elliptic Curve Cryptography implementations on Graphics Processing Units (GPUs have been researched for over a decade. The basic idea of most previous contributions is exploiting the highly parallel GPU architecture and porting the integer-based algorithms from general-purpose CPUs to GPUs, to offer high performance. However, the great potential cryptographic computing power of GPUs, especially by the more powerful floating-point instructions, has not been comprehensively investigated in fact. In this paper, we fully exploit the floating-point computing power of GPUs, by various designs, including the floating-point-based Montgomery multiplication/exponentiation algorithm and Chinese Remainder Theorem (CRT implementation in GPU. And for practical usage of the proposed algorithm, a new method is performed to convert the input/output between octet strings and floating-point numbers, fully utilizing GPUs and further promoting the overall performance by about 5%. The performance of RSA-2048/3072/4096 decryption on NVIDIA GeForce GTX TITAN reaches 42,211/12,151/5,790 operations per second, respectively, which achieves 13 times the performance of the previous fastest floating-point-based implementation (published in Eurocrypt 2009. The RSA-4096 decryption precedes the existing fastest integer-based result by 23%.

  16. Detection of uterine MMG contractions using a multiple change point estimator and the K-means cluster algorithm.

    Science.gov (United States)

    La Rosa, Patricio S; Nehorai, Arye; Eswaran, Hari; Lowery, Curtis L; Preissl, Hubert

    2008-02-01

    We propose a single channel two-stage time-segment discriminator of uterine magnetomyogram (MMG) contractions during pregnancy. We assume that the preprocessed signals are piecewise stationary having distribution in a common family with a fixed number of parameters. Therefore, at the first stage, we propose a model-based segmentation procedure, which detects multiple change-points in the parameters of a piecewise constant time-varying autoregressive model using a robust formulation of the Schwarz information criterion (SIC) and a binary search approach. In particular, we propose a test statistic that depends on the SIC, derive its asymptotic distribution, and obtain closed-form optimal detection thresholds in the sense of the Neyman-Pearson criterion; therefore, we control the probability of false alarm and maximize the probability of change-point detection in each stage of the binary search algorithm. We compute and evaluate the relative energy variation [root mean squares (RMS)] and the dominant frequency component [first order zero crossing (FOZC)] in discriminating between time segments with and without contractions. The former consistently detects a time segment with contractions. Thus, at the second stage, we apply a nonsupervised K-means cluster algorithm to classify the detected time segments using the RMS values. We apply our detection algorithm to real MMG records obtained from ten patients admitted to the hospital for contractions with gestational ages between 31 and 40 weeks. We evaluate the performance of our detection algorithm in computing the detection and false alarm rate, respectively, using as a reference the patients' feedback. We also analyze the fusion of the decision signals from all the sensors as in the parallel distributed detection approach.

  17. Influences of sodium carbonate on physicochemical properties of lansoprazole in designed multiple coating pellets.

    Science.gov (United States)

    He, Wei; Yang, Min; Fan, Jun Hong; Feng, Cai Xia; Zhang, Su Juan; Wang, Jin Xu; Guan, Pei Pei; Wu, Wei

    2010-09-01

    Lansoprazole (LSP), a proton-pump inhibitor, belongs to class II drug. It is especially instable to heat, light, and acidic media, indicating that fabrication of a formulation stabilizing the drug is difficult. The addition of alkaline stabilizer is the most powerful method to protect the drug in solid formulations under detrimental environment. The purpose of the study was to characterize the designed multiple coating pellets of LSP containing an alkaline stabilizer (sodium carbonate) and assess the effect of the stabilizer on the physicochemical properties of the drug. The coated pellets were prepared by layer-layer film coating with a fluid-bed coater. In vitro release and acid-resistance studies were carried out in simulated gastric fluid and simulated intestinal fluid, respectively. Furthermore, the moisture-uptake test was performed to evaluate the influence of sodium carbonate on the drug stability. The results indicate that the drug exists in the amorphous state or small (nanometer size) particles without crystallization even after storage at 40°C/75% for 5 months. The addition of sodium carbonate to the pellet protects the drug from degradation in simulated gastric fluid in a dose-dependent manner. The moisture absorbed into the pellets has a detrimental effect on the drug stability. The extent of drug degradation is directly correlated with the content of moisture absorption. In conclusion, these results suggest that the presence of sodium carbonate influence the physicochemical properties of LSP, and the designed multiple coating pellets enhance the drug stability.

  18. Zero-Point Energy Constraint for Unimolecular Dissociation Reactions. Giving Trajectories Multiple Chances To Dissociate Correctly.

    Science.gov (United States)

    Paul, Amit K; Hase, William L

    2016-01-28

    A zero-point energy (ZPE) constraint model is proposed for classical trajectory simulations of unimolecular decomposition and applied to CH4* → H + CH3 decomposition. With this model trajectories are not allowed to dissociate unless they have ZPE in the CH3 product. If not, they are returned to the CH4* region of phase space and, if necessary, given additional opportunities to dissociate with ZPE. The lifetime for dissociation of an individual trajectory is the time it takes to dissociate with ZPE in CH3, including multiple possible returns to CH4*. With this ZPE constraint the dissociation of CH4* is exponential in time as expected for intrinsic RRKM dynamics and the resulting rate constant is in good agreement with the harmonic quantum value of RRKM theory. In contrast, a model that discards trajectories without ZPE in the reaction products gives a CH4* → H + CH3 rate constant that agrees with the classical and not quantum RRKM value. The rate constant for the purely classical simulation indicates that anharmonicity may be important and the rate constant from the ZPE constrained classical trajectory simulation may not represent the complete anharmonicity of the RRKM quantum dynamics. The ZPE constraint model proposed here is compared with previous models for restricting ZPE flow in intramolecular dynamics, and connecting product and reactant/product quantum energy levels in chemical dynamics simulations.

  19. Parallel Beam-Beam Simulation Incorporating Multiple Bunches and Multiple Interaction Regions

    CERN Document Server

    Jones, F W; Pieloni, T

    2007-01-01

    The simulation code COMBI has been developed to enable the study of coherent beam-beam effects in the full collision scenario of the LHC, with multiple bunches interacting at multiple crossing points over many turns. The program structure and input are conceived in a general way which allows arbitrary numbers and placements of bunches and interaction points (IP's), together with procedural options for head-on and parasitic collisions (in the strong-strong sense), beam transport, statistics gathering, harmonic analysis, and periodic output of simulation data. The scale of this problem, once we go beyond the simplest case of a pair of bunches interacting once per turn, quickly escalates into the parallel computing arena, and herein we will describe the construction of an MPI-based version of COMBI able to utilize arbitrary numbers of processors to support efficient calculation of multi-bunch multi-IP interactions and transport. Implementing the parallel version did not require extensive disruption of the basic ...

  20. Development of a multicomponent Staphylococcus aureus vaccine designed to counter multiple bacterial virulence factors

    Science.gov (United States)

    Anderson, Annaliesa S.; Miller, Alita A.; Donald, Robert G.K.; Scully, Ingrid L.; Nanra, Jasdeep S.; Cooper, David; Jansen, Kathrin U.

    2012-01-01

    Staphylococcus aureus is a major cause of healthcare-associated infections and is responsible for a substantial burden of disease in hospitalized patients. Despite increasingly rigorous infection control guidelines, the prevalence and corresponding negative impact of S. aureus infections remain considerable. Difficulties in controlling S. aureus infections as well as the associated treatment costs are exacerbated by increasing rates of resistance to available antibiotics. Despite ongoing efforts over the past 20 years, no licensed S. aureus vaccine is currently available. However, learnings from past clinical failures of vaccine candidates and a better understanding of the immunopathology of S. aureus colonization and infection have aided in the design of new vaccine candidates based on multiple important bacterial pathogenesis mechanisms. This review outlines important considerations in designing a vaccine for the prevention of S. aureus disease in healthcare settings. PMID:22922765

  1. Apollo: giving application developers a single point of access to public health models using structured vocabularies and Web services.

    Science.gov (United States)

    Wagner, Michael M; Levander, John D; Brown, Shawn; Hogan, William R; Millett, Nicholas; Hanna, Josh

    2013-01-01

    This paper describes the Apollo Web Services and Apollo-SV, its related ontology. The Apollo Web Services give an end-user application a single point of access to multiple epidemic simulators. An end user can specify an analytic problem-which we define as a configuration and a query of results-exactly once and submit it to multiple epidemic simulators. The end user represents the analytic problem using a standard syntax and vocabulary, not the native languages of the simulators. We have demonstrated the feasibility of this design by implementing a set of Apollo services that provide access to two epidemic simulators and two visualizer services.

  2. Visualizing Matrix Multiplication

    Science.gov (United States)

    Daugulis, Peteris; Sondore, Anita

    2018-01-01

    Efficient visualizations of computational algorithms are important tools for students, educators, and researchers. In this article, we point out an innovative visualization technique for matrix multiplication. This method differs from the standard, formal approach by using block matrices to make computations more visual. We find this method a…

  3. Operational procedure for computer program for design point characteristics of a compressed-air generator with through-flow combustor for V/STOL applications

    Science.gov (United States)

    Krebs, R. P.

    1971-01-01

    The computer program described in this report calculates the design-point characteristics of a compressed-air generator for use in V/STOL applications such as systems with a tip-turbine-driven lift fan. The program computes the dimensions and mass, as well as the thermodynamic performance of a model air generator configuration which involves a straight through-flow combustor. Physical and thermodynamic characteristics of the air generator components are also given. The program was written in FORTRAN IV language. Provision has been made so that the program will accept input values in either SI units or U.S. customary units. Each air generator design-point calculation requires about 1.5 seconds of 7094 computer time for execution.

  4. FireProt: web server for automated design of thermostable proteins

    Science.gov (United States)

    Musil, Milos; Stourac, Jan; Brezovsky, Jan; Prokop, Zbynek; Zendulka, Jaroslav; Martinek, Tomas

    2017-01-01

    Abstract There is a continuous interest in increasing proteins stability to enhance their usability in numerous biomedical and biotechnological applications. A number of in silico tools for the prediction of the effect of mutations on protein stability have been developed recently. However, only single-point mutations with a small effect on protein stability are typically predicted with the existing tools and have to be followed by laborious protein expression, purification, and characterization. Here, we present FireProt, a web server for the automated design of multiple-point thermostable mutant proteins that combines structural and evolutionary information in its calculation core. FireProt utilizes sixteen tools and three protein engineering strategies for making reliable protein designs. The server is complemented with interactive, easy-to-use interface that allows users to directly analyze and optionally modify designed thermostable mutants. FireProt is freely available at http://loschmidt.chemi.muni.cz/fireprot. PMID:28449074

  5. Roadside Multiple Objects Extraction from Mobile Laser Scanning Point Cloud Based on DBN

    Directory of Open Access Journals (Sweden)

    LUO Haifeng

    2018-02-01

    Full Text Available This paper proposed an novel algorithm for exploring deep belief network (DBN architectures to extract and recognize roadside facilities (trees,cars and traffic poles from mobile laser scanning (MLS point cloud.The proposed methods firstly partitioned the raw MLS point cloud into blocks and then removed the ground and building points.In order to partition the off-ground objects into individual objects,off-ground points were organized into an Octree structure and clustered into candidate objects based on connected component.To improve segmentation performance on clusters containing overlapped objects,a refining processing using a voxel-based normalized cut was then implemented.In addition,multi-view features descriptor was generated for each independent roadside facilities based on binary images.Finally,a deep belief network (DBN was trained to extract trees,cars and traffic pole objects.Experiments are undertaken to evaluate the validities of the proposed method with two datasets acquired by Lynx Mobile Mapper System.The precision of trees,cars and traffic poles objects extraction results respectively was 97.31%,97.79% and 92.78%.The recall was 98.30%,98.75% and 96.77% respectively.The quality is 95.70%,93.81% and 90.00%.And the F1 measure was 97.80%,96.81% and 94.73%.

  6. A point-wise fiber Bragg grating displacement sensing system and its application for active vibration suppression of a smart cantilever beam subjected to multiple impact loadings

    International Nuclear Information System (INIS)

    Chuang, Kuo-Chih; Ma, Chien-Ching; Liao, Heng-Tseng

    2012-01-01

    In this work, active vibration suppression of a smart cantilever beam subjected to disturbances from multiple impact loadings is investigated with a point-wise fiber Bragg grating (FBG) displacement sensing system. An FBG demodulator is employed in the proposed fiber sensing system to dynamically demodulate the responses obtained by the FBG displacement sensor with high sensitivity. To investigate the ability of the proposed FBG displacement sensor as a feedback sensor, velocity feedback control and delay control are employed to suppress the vibrations of the first three bending modes of the smart cantilever beam. To improve the control performance for the first bending mode when the cantilever beam is subjected to an impact loading, we improve the conventional velocity feedback controller by tuning the control gain online with the aid of information from a higher vibration mode. Finally, active control of vibrations induced by multiple impact loadings due to a plastic ball is performed with the improved velocity feedback control. The experimental results show that active vibration control of smart structures subjected to disturbances such as impact loadings can be achieved by employing the proposed FBG sensing system to feed back out-of-plane point-wise displacement responses with high sensitivity. (paper)

  7. Robust design method and thermostatic experiment for multiple piezoelectric vibration absorber system

    International Nuclear Information System (INIS)

    Nambu, Yohsuke; Takashima, Toshihide; Inagaki, Akiya

    2015-01-01

    This paper examines the effects of connecting multiplexing shunt circuits composed of inductors and resistors to piezoelectric transducers so as to improve the robustness of a piezoelectric vibration absorber (PVA). PVAs are well known to be effective at suppressing the vibration of an adaptive structure; their weakness is low robustness to changes in the dynamic parameters of the system, including the main structure and the absorber. In the application to space structures, the temperature-dependency of capacitance of piezoelectric ceramics is the factor that causes performance reduction. To improve robustness to the temperature-dependency of the capacitance, this paper proposes a multiple-PVA system that is composed of distributed piezoelectric transducers and several shunt circuits. The optimization problems that determine both the frequencies and the damping ratios of the PVAs are multi-objective problems, which are solved using a real-coded genetic algorithm in this paper. A clamped aluminum beam with four groups of piezoelectric ceramics attached was considered in simulations and experiments. Numerical simulations revealed that the PVA systems designed using the proposed method had tolerance to changes in the capacitances. Furthermore, experiments using a thermostatic bath were conducted to reveal the effectiveness and robustness of the PVA systems. The maximum peaks of the transfer functions of the beam with the open circuit, the single-PVA system, the double-PVA system, and the quadruple-PVA system at 20 °C were 14.3 dB, −6.91 dB, −7.47 dB, and −8.51 dB, respectively. The experimental results also showed that the multiple-PVA system is more robust than a single PVA in a variable temperature environment from −10 °C to 50 °C. In conclusion, the use of multiple PVAs results in an effective, robust vibration control method for adaptive structures. (paper)

  8. Interval Mathematics Applied to Critical Point Transitions

    Directory of Open Access Journals (Sweden)

    Benito A. Stradi

    2012-03-01

    Full Text Available The determination of critical points of mixtures is important for both practical and theoretical reasons in the modeling of phase behavior, especially at high pressure. The equations that describe the behavior of complex mixtures near critical points are highly nonlinear and with multiplicity of solutions to the critical point equations. Interval arithmetic can be used to reliably locate all the critical points of a given mixture. The method also verifies the nonexistence of a critical point if a mixture of a given composition does not have one. This study uses an interval Newton/Generalized Bisection algorithm that provides a mathematical and computational guarantee that all mixture critical points are located. The technique is illustrated using several example problems. These problems involve cubic equation of state models; however, the technique is general purpose and can be applied in connection with other nonlinear problems.

  9. The Tipping Points of Technology Development

    Directory of Open Access Journals (Sweden)

    Tauno Kekäle

    2014-07-01

    Full Text Available The tipping point, the decisive point in time in the competition between old and new, is an interesting phenomenon in physics of today. This aspect in technology acceptance is connected to many business decisions such as technology investments, product releases, resource allocation, sales forecasts and, ultimately, affects the profitability and even survival of a company. The tipping point itself is based on many stochastic and dynamic variables, and the process may at least partly be described as path-dependent. This paper analyses the tipping point from three aspects: (1 product performance, (2 features of the market and infrastructure (including related technologies and human network externalities, and (3 actions of the incumbents (including customer lock-in, systems lock-in, and sustaining innovation. The paper is based on the Bass s-curve idea and the technology trajectory concept proposed by Dosi. Three illustrative cases are presented to make the point of the multiple factors affecting technology acceptance and, thus, the tipping point. The paper also suggests outlines for further research in field of computer simulation.

  10. Care Model Design for E-Health: Integration of Point-of-Care Testing at Dutch General Practices

    Directory of Open Access Journals (Sweden)

    Bart Verhees

    2017-12-01

    Full Text Available Point-of-care testing (POCT—laboratory tests performed with new mobile devices and online technologies outside of the central laboratory—is rapidly outpacing the traditional laboratory test market, growing at a rate of 12 to 15% each year. POCT impacts the diagnostic process of care providers by yielding high efficiency benefits in terms of turnaround time and related quality improvements in the reduction of errors. However, the implementation of this disruptive eHealth technology requires the integration and transformation of diagnostic services across the boundaries of healthcare organizations. Research has revealed both advantages and barriers of POCT implementations, yet to date, there is no business model for the integration of POCT within general practice. The aim of this article is to contribute with a design for a care model that enables the integration of POCT in primary healthcare. In this research, we used a design modelling toolkit for data collection at five general practices. Through an iterative design process, we modelled the actors and value transactions, and designed an optimized care model for the dynamic integration of POCTs into the GP’s network of care delivery. The care model design will have a direct bearing on improving the integration of POCT through the connectivity and norm guidelines between the general practice, the POC technology, and the diagnostic centre.

  11. Care Model Design for E-Health: Integration of Point-of-Care Testing at Dutch General Practices.

    Science.gov (United States)

    Verhees, Bart; van Kuijk, Kees; Simonse, Lianne

    2017-12-21

    Point-of-care testing (POCT)-laboratory tests performed with new mobile devices and online technologies outside of the central laboratory-is rapidly outpacing the traditional laboratory test market, growing at a rate of 12 to 15% each year. POCT impacts the diagnostic process of care providers by yielding high efficiency benefits in terms of turnaround time and related quality improvements in the reduction of errors. However, the implementation of this disruptive eHealth technology requires the integration and transformation of diagnostic services across the boundaries of healthcare organizations. Research has revealed both advantages and barriers of POCT implementations, yet to date, there is no business model for the integration of POCT within general practice. The aim of this article is to contribute with a design for a care model that enables the integration of POCT in primary healthcare. In this research, we used a design modelling toolkit for data collection at five general practices. Through an iterative design process, we modelled the actors and value transactions, and designed an optimized care model for the dynamic integration of POCTs into the GP's network of care delivery. The care model design will have a direct bearing on improving the integration of POCT through the connectivity and norm guidelines between the general practice, the POC technology, and the diagnostic centre.

  12. NIF Ignition Target 3D Point Design

    Energy Technology Data Exchange (ETDEWEB)

    Jones, O; Marinak, M; Milovich, J; Callahan, D

    2008-11-05

    We have developed an input file for running 3D NIF hohlraums that is optimized such that it can be run in 1-2 days on parallel computers. We have incorporated increasing levels of automation into the 3D input file: (1) Configuration controlled input files; (2) Common file for 2D and 3D, different types of capsules (symcap, etc.); and (3) Can obtain target dimensions, laser pulse, and diagnostics settings automatically from NIF Campaign Management Tool. Using 3D Hydra calculations to investigate different problems: (1) Intrinsic 3D asymmetry; (2) Tolerance to nonideal 3D effects (e.g. laser power balance, pointing errors); and (3) Synthetic diagnostics.

  13. Application of multiple-point geostatistics to simulate the effect of small scale aquifer heterogeneity on the efficiency of Aquifer Thermal Energy Storage (ATES)

    Science.gov (United States)

    Possemiers, Mathias; Huysmans, Marijke; Batelaan, Okke

    2015-04-01

    Adequate aquifer characterization and simulation using heat transport models are indispensible for determining the optimal design for Aquifer Thermal Energy Storage (ATES) systems and wells. Recent model studies indicate that meter scale heterogeneities in the hydraulic conductivity field introduce a considerable uncertainty in the distribution of thermal energy around an ATES system and can lead to a reduction in the thermal recoverability. In this paper, the influence of centimeter scale clay drapes on the efficiency of a doublet ATES system and the distribution of the thermal energy around the ATES wells are quantified. Multiple-point geostatistical simulation of edge properties is used to incorporate the clay drapes in the models. The results show that clay drapes have an influence both on the distribution of thermal energy in the subsurface and on the efficiency of the ATES system. The distribution of the thermal energy is determined by the strike of the clay drapes, with the major axis of anisotropy parallel to the clay drape strike. The clay drapes have a negative impact (3.3 - 3.6%) on the energy output in the models without a hydraulic gradient. In the models with a hydraulic gradient, however, the presence of clay drapes has a positive influence (1.6 - 10.2%) on the energy output of the ATES system. It is concluded that it is important to incorporate small scale heterogeneities in heat transport models to get a better estimate on ATES efficiency and distribution of thermal energy.

  14. Focal points and principal solutions of linear Hamiltonian systems revisited

    Science.gov (United States)

    Šepitka, Peter; Šimon Hilscher, Roman

    2018-05-01

    In this paper we present a novel view on the principal (and antiprincipal) solutions of linear Hamiltonian systems, as well as on the focal points of their conjoined bases. We present a new and unified theory of principal (and antiprincipal) solutions at a finite point and at infinity, and apply it to obtain new representation of the multiplicities of right and left proper focal points of conjoined bases. We show that these multiplicities can be characterized by the abnormality of the system in a neighborhood of the given point and by the rank of the associated T-matrix from the theory of principal (and antiprincipal) solutions. We also derive some additional important results concerning the representation of T-matrices and associated normalized conjoined bases. The results in this paper are new even for completely controllable linear Hamiltonian systems. We also discuss other potential applications of our main results, in particular in the singular Sturmian theory.

  15. Detecting Change-Point via Saddlepoint Approximations

    Institute of Scientific and Technical Information of China (English)

    Zhaoyuan LI; Maozai TIAN

    2017-01-01

    It's well-known that change-point problem is an important part of model statistical analysis.Most of the existing methods are not robust to criteria of the evaluation of change-point problem.In this article,we consider "mean-shift" problem in change-point studies.A quantile test of single quantile is proposed based on saddlepoint approximation method.In order to utilize the information at different quantile of the sequence,we further construct a "composite quantile test" to calculate the probability of every location of the sequence to be a change-point.The location of change-point can be pinpointed rather than estimated within a interval.The proposed tests make no assumptions about the functional forms of the sequence distribution and work sensitively on both large and small size samples,the case of change-point in the tails,and multiple change-points situation.The good performances of the tests are confirmed by simulations and real data analysis.The saddlepoint approximation based distribution of the test statistic that is developed in the paper is of independent interest and appealing.This finding may be of independent interest to the readers in this research area.

  16. Rehabilitation and multiple sclerosis

    DEFF Research Database (Denmark)

    Dalgas, Ulrik

    2011-01-01

    In a chronic and disabling disease like multiple sclerosis, rehabilitation becomes of major importance in the preservation of physical, psychological and social functioning. Approximately 80% of patients have multiple sclerosis for more than 35 years and most will develop disability at some point......, a paradigm shift is taking place and it is now increasingly acknowledged that exercise therapy is both safe and beneficial. Robot-assisted training is also attracting attention in multiple sclerosis rehabilitation. Several sophisticated commercial robots exist, but so far the number of scientific studies...... promising. This drug has been shown to improve walking ability in some patients with multiple sclerosis, associated with a reduction of patients' self-reported ambulatory disability. Rehabilitation strategies involving these different approaches, or combinations of them, may be of great use in improving...

  17. Floating point only SIMD instruction set architecture including compare, select, Boolean, and alignment operations

    Science.gov (United States)

    Gschwind, Michael K [Chappaqua, NY

    2011-03-01

    Mechanisms for implementing a floating point only single instruction multiple data instruction set architecture are provided. A processor is provided that comprises an issue unit, an execution unit coupled to the issue unit, and a vector register file coupled to the execution unit. The execution unit has logic that implements a floating point (FP) only single instruction multiple data (SIMD) instruction set architecture (ISA). The floating point vector registers of the vector register file store both scalar and floating point values as vectors having a plurality of vector elements. The processor may be part of a data processing system.

  18. Control room conceptual design of nuclear power plant with multiple modular high temperature gas-cooled reactors

    International Nuclear Information System (INIS)

    Jia Qianqian; Qu Ronghong; Zhang Liangju

    2014-01-01

    A conceptual design of the control room layout for the nuclear power plant with multiple modular high temperature gas-cooled reactors has been developed. The modular high temperature gas-cooled reactors may need to be grouped to produce as much energy as a utility demands to realize the economic efficiency. There are many differences between the multi-modular plant and the current NPPs in the control room. These differences may include the staffing level, the human-machine interface design, the operation mode, etc. The potential challenges of the human factor engineering (HFE) in the control room of the multi-modular plant are analyzed, including the operation workload of the multi-modular tasks, how to help the crew to keep situation awareness of all modules, and how to support team work, the control of shared system between modules, etc. A concept design of control room for the multi-modular plant is presented based on the design aspect of HTR-PM (High temperature gas-cooled reactor pebble bed module). HFE issues are considered in the conceptual design of control room for the multi-modular plant and some design strategies are presented. As a novel conceptual design, verifications and validations are needed, and focus of further work is sketch out. (author)

  19. A national assessment of underground natural gas storage: identifying wells with designs likely vulnerable to a single-point-of-failure

    Science.gov (United States)

    Michanowicz, Drew R.; Buonocore, Jonathan J.; Rowland, Sebastian T.; Konschnik, Katherine E.; Goho, Shaun A.; Bernstein, Aaron S.

    2017-05-01

    The leak of processed natural gas (PNG) from October 2015 to February 2016 from the Aliso Canyon storage facility, near Los Angeles, California, was the largest single accidental release of greenhouse gases in US history. The Interagency Task Force on Natural Gas Storage Safety and California regulators recently recommended operators phase out single-point-of-failure (SPF) well designs. Here, we develop a national dataset of UGS well activity in the continental US to assess regulatory data availability and uncertainty, and to assess the prevalence of certain well design deficiencies including single-point-of-failure designs. We identified 14 138 active UGS wells associated with 317 active UGS facilities in 29 states using regulatory and company data. State-level wellbore datasets contained numerous reporting inconsistencies that limited data concatenation. We identified 2715 active UGS wells across 160 facilities that, like the failed well at Aliso Canyon, predated the storage facility, and therefore were not originally designed for gas storage. The majority (88%) of these repurposed wells are located in OH, MI, PA, NY, and WV. Repurposed wells have a median age of 74 years, and the 2694 repurposed wells constructed prior to 1979 are particularly likely to exhibit design-related deficiencies. An estimated 210 active repurposed wells were constructed before 1917—before cement zonal isolation methods were utilized. These wells are located in OH, PA, NY, and WV and represent the highest priority related to potential design deficiencies that could lead to containment loss. This national baseline assessment identifies regulatory data uncertainties, highlights a potentially widespread vulnerability of the natural gas supply chain, and can aid in prioritization and oversight for high-risk wells and facilities.

  20. Application of multiple-point geostatistics to simulate the effect of small-scale aquifer heterogeneity on the efficiency of aquifer thermal energy storage

    Science.gov (United States)

    Possemiers, Mathias; Huysmans, Marijke; Batelaan, Okke

    2015-08-01

    Adequate aquifer characterization and simulation using heat transport models are indispensible for determining the optimal design for aquifer thermal energy storage (ATES) systems and wells. Recent model studies indicate that meter-scale heterogeneities in the hydraulic conductivity field introduce a considerable uncertainty in the distribution of thermal energy around an ATES system and can lead to a reduction in the thermal recoverability. In a study site in Bierbeek, Belgium, the influence of centimeter-scale clay drapes on the efficiency of a doublet ATES system and the distribution of the thermal energy around the ATES wells are quantified. Multiple-point geostatistical simulation of edge properties is used to incorporate the clay drapes in the models. The results show that clay drapes have an influence both on the distribution of thermal energy in the subsurface and on the efficiency of the ATES system. The distribution of the thermal energy is determined by the strike of the clay drapes, with the major axis of anisotropy parallel to the clay drape strike. The clay drapes have a negative impact (3.3-3.6 %) on the energy output in the models without a hydraulic gradient. In the models with a hydraulic gradient, however, the presence of clay drapes has a positive influence (1.6-10.2 %) on the energy output of the ATES system. It is concluded that it is important to incorporate small-scale heterogeneities in heat transport models to get a better estimate on ATES efficiency and distribution of thermal energy.

  1. Designing an Electronic Patient Management System for Multiple Sclerosis: Building a Next Generation Multiple Sclerosis Documentation System.

    Science.gov (United States)

    Kern, Raimar; Haase, Rocco; Eisele, Judith Christina; Thomas, Katja; Ziemssen, Tjalf

    2016-01-08

    Technologies like electronic health records or telemedicine devices support the rapid mediation of health information and clinical data independent of time and location between patients and their physicians as well as among health care professionals. Today, every part of the treatment process from diagnosis, treatment selection, and application to patient education and long-term care may be enhanced by a quality-assured implementation of health information technology (HIT) that also takes data security standards and concerns into account. In order to increase the level of effectively realized benefits of eHealth services, a user-driven needs assessment should ensure the inclusion of health care professional perspectives into the process of technology development as we did in the development process of the Multiple Sclerosis Documentation System 3D. After analyzing the use of information technology by patients suffering from multiple sclerosis, we focused on the needs of neurological health care professionals and their handling of health information technology. Therefore, we researched the status quo of eHealth adoption in neurological practices and clinics as well as health care professional opinions about potential benefits and requirements of eHealth services in the field of multiple sclerosis. We conducted a paper-and-pencil-based mail survey in 2013 by sending our questionnaire to 600 randomly chosen neurological practices in Germany. The questionnaire consisted of 24 items covering characteristics of participating neurological practices (4 items), the current use of network technology and the Internet in such neurological practices (5 items), physicians' attitudes toward the general and MS-related usefulness of eHealth systems (8 items) and toward the clinical documentation via electronic health records (4 items), and physicians' knowledge about the Multiple Sclerosis Documentation System (3 items). From 600 mailed surveys, 74 completed surveys were returned

  2. SharePoint User's Guide

    CERN Document Server

    Corporation, Infusion Development

    2009-01-01

    This straightforward guide shows SharePoint users how to create and use web sites for sharing and collaboration. Learn to use the document and picture libraries for adding and editing content, add discussion boards and surveys, receive alerts when documents and information have been added or changed, and enhance security. Designed to help you find answers quickly, the book shows how to make the most of SharePoint for productivity and collaboration.

  3. Watershed-based survey designs

    Science.gov (United States)

    Detenbeck, N.E.; Cincotta, D.; Denver, J.M.; Greenlee, S.K.; Olsen, A.R.; Pitchford, A.M.

    2005-01-01

    Watershed-based sampling design and assessment tools help serve the multiple goals for water quality monitoring required under the Clean Water Act, including assessment of regional conditions to meet Section 305(b), identification of impaired water bodies or watersheds to meet Section 303(d), and development of empirical relationships between causes or sources of impairment and biological responses. Creation of GIS databases for hydrography, hydrologically corrected digital elevation models, and hydrologic derivatives such as watershed boundaries and upstream–downstream topology of subcatchments would provide a consistent seamless nationwide framework for these designs. The elements of a watershed-based sample framework can be represented either as a continuous infinite set defined by points along a linear stream network, or as a discrete set of watershed polygons. Watershed-based designs can be developed with existing probabilistic survey methods, including the use of unequal probability weighting, stratification, and two-stage frames for sampling. Case studies for monitoring of Atlantic Coastal Plain streams, West Virginia wadeable streams, and coastal Oregon streams illustrate three different approaches for selecting sites for watershed-based survey designs.

  4. Design of high-order all-optical temporal differentiators based on multiple-phase-shifted fiber Bragg gratings.

    Science.gov (United States)

    Kulishov, Mykola; Azaña, José

    2007-05-14

    A simple and general approach for designing practical all-optical (all-fiber) arbitrary-order time differentiators is introduced here for the first time. Specifically, we demonstrate that the Nth time derivative of an input optical waveform can be obtained by reflection of this waveform in a single uniform fiber Bragg grating (FBG) incorporating N &pi-phase shifts properly located along its grating profile. The general design procedure of an arbitrary-order optical time differentiator based on a multiple-phase-shifted FBG is described and numerically demonstrated for up to fourth-order time differentiation. Our simulations show that the proposed approach can provide optical operation bandwidths in the tens-of-GHz regime using readily feasible FBG structures.

  5. Robust structural design against self-excited vibrations

    CERN Document Server

    Spelsberg-Korspeter, Gottfried

    2013-01-01

    This book studies methods for a robust design of rotors against self-excited vibrations. The occurrence of self-excited vibrations in engineering applications if often unwanted and in many cases difficult to model. Thinking of complex systems such as machines with many components and mechanical contacts, it is important to have guidelines for design so that the functionality is robust against small imperfections. This book discusses the question on how to design a structure such that unwanted self-excited vibrations do not occur. It shows theoretically and practically that the old design rule to avoid multiple eigenvalues points toward the right direction and have optimized structures accordingly. This extends results for the well-known flutter problem in which equations of motion with constant coefficients occur to the case of a linear conservative system with arbitrary time periodic perturbations.

  6. A quartz crystal microbalance dew point sensor without frequency measurement

    Science.gov (United States)

    Wang, Guohua; Zhang, Weishuo; Wang, Shuo; Sun, Jinglin

    2014-11-01

    This work deals with the design of a dew point sensor based on Quartz Crystal Microbalance (QCM) without measuring the frequency. This idea is inspired by the fact that the Colpitts oscillation circuit will stop oscillating when the QCM works in the liquid media. The quartz crystal and the electrode are designed through the finite element simulation and the stop oscillating experiment is conducted to verify the sensibility. Moreover, the measurement result is calibrated to approach the true value. At last a series of dew points at the same temperature is measured with the designed sensor. Results show that the designed dew point sensor is able to detect the dew point with the proper accuracy.

  7. Multiple Sclerosis Cerebrospinal Fluid Biomarkers

    Directory of Open Access Journals (Sweden)

    Gavin Giovannoni

    2006-01-01

    Full Text Available Cerebrospinal fluid (CSF is the body fluid closest to the pathology of multiple sclerosis (MS. For many candidate biomarkers CSF is the only fluid that can be investigated. Several factors need to be standardized when sampling CSF for biomarker research: time/volume of CSF collection, sample processing/storage, and the temporal relationship of sampling to clinical or MRI markers of disease activity. Assays used for biomarker detection must be validated so as to optimize the power of the studies. A formal method for establishing whether or not a particular biomarker can be used as a surrogate end-point needs to be adopted. This process is similar to that used in clinical trials, where the reporting of studies has to be done in a standardized way with sufficient detail to permit a critical review of the study and to enable others to reproduce the study design. A commitment must be made to report negative studies so as to prevent publication bias. Pre-defined consensus criteria need to be developed for MS-related prognostic biomarkers. Currently no candidate biomarker is suitable as a surrogate end-point. Bulk biomarkers of the neurodegenerative process such as glial fibrillary acidic protein (GFAP and neurofilaments (NF have advantages over intermittent inflammatory markers.

  8. Optimal Halbach permanent magnet designs for maximally pulling and pushing nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Sarwar, A., E-mail: azeem@umd.edu [Fischell Department of Bioengineering, College Park, MD (United States); University of Maryland at College Park (United States); Nemirovski, A. [H. Milton Stewart School of Industrial and Systems Engineering (ISyE), Georgia Institute of Technology (United States); Shapiro, B. [Fischell Department of Bioengineering, College Park, MD (United States); Institute for Systems Research (United States); University of Maryland at College Park (United States)

    2012-03-15

    Optimization methods are presented to design Halbach arrays to maximize the forces applied on magnetic nanoparticles at deep tissue locations. In magnetic drug targeting, where magnets are used to focus therapeutic nanoparticles to disease locations, the sharp fall off of magnetic fields and forces with distances from magnets has limited the depth of targeting. Creating stronger forces at a depth by optimally designed Halbach arrays would allow treatment of a wider class of patients, e.g. patients with deeper tumors. The presented optimization methods are based on semi-definite quadratic programming, yield provably globally optimal Halbach designs in 2 and 3-dimensions, for maximal pull or push magnetic forces (stronger pull forces can collect nanoparticles against blood forces in deeper vessels; push forces can be used to inject particles into precise locations, e.g. into the inner ear). These Halbach designs, here tested in simulations of Maxwell's equations, significantly outperform benchmark magnets of the same size and strength. For example, a 3-dimensional 36 element 2000 cm{sup 3} volume optimal Halbach design yields a 5 Multiplication-Sign greater force at a 10 cm depth compared to a uniformly magnetized magnet of the same size and strength. The designed arrays should be feasible to construct, as they have a similar strength ({<=}1 T), size ({<=}2000 cm{sup 3}), and number of elements ({<=}36) as previously demonstrated arrays, and retain good performance for reasonable manufacturing errors (element magnetization direction errors {<=}5 Degree-Sign), thus yielding practical designs to improve magnetic drug targeting treatment depths. - Highlights: Black-Right-Pointing-Pointer Optimization methods presented to design Halbach arrays for drug targeting. Black-Right-Pointing-Pointer The goal is to maximize forces on magnetic nanoparticles at deep tissue locations. Black-Right-Pointing-Pointer The presented methods yield provably globally optimal Halbach

  9. FDM and DMT performance comparison in high capacity point-to-point fibre links for intra/inter-datacentre connections

    Science.gov (United States)

    Gatto, A.; Parolari, P.; Boffi, P.

    2018-05-01

    Frequency division multiplexing (FDM) is attractive to achieve high capacities in multiple access networks characterized by direct modulation and direct detection. In this paper we take into account point-to-point intra- and inter-datacenter connections to understand the performance of FDM operation compared with the ones achievable with standard multiple carrier modulation approach based on discrete multitone (DMT). DMT and FDM allow to match the non-uniform and bandwidth-limited response of the system under test, associated with the employment of low-cost directly-modulated sources, such as VCSELs with high-frequency chirp, and with fibre-propagation in presence of chromatic dispersion. While for very short distances typical of intra-datacentre communications, the huge number of DMT subcarriers permits to increase the transported capacity with respect to the FDM employment, in case of few tens-km reaches typical of inter-datacentre connections, the capabilities of FDM are more evident, providing system performance similar to the case of DMT application.

  10. Teaching Structure-Property Relationships: Investigating Molecular Structure and Boiling Point

    Science.gov (United States)

    Murphy, Peter M.

    2007-01-01

    A concise, well-organized table of the boiling points of 392 organic compounds has facilitated inquiry-based instruction in multiple scientific principles. Many individual or group learning activities can be derived from the tabulated data of molecular structure and boiling point based on the instructor's education objectives and the students'…

  11. Time-Lapse Analysis of Methane Quantity in the Mary Lee Group of Coal Seams Using Filter-Based Multiple-Point Geostatistical Simulation.

    Science.gov (United States)

    Karacan, C Özgen; Olea, Ricardo A

    2013-08-01

    Coal seam degasification and its success are important for controlling methane, and thus for the health and safety of coal miners. During the course of degasification, properties of coal seams change. Thus, the changes in coal reservoir conditions and in-place gas content as well as methane emission potential into mines should be evaluated by examining time-dependent changes and the presence of major heterogeneities and geological discontinuities in the field. In this work, time-lapsed reservoir and fluid storage properties of the New Castle coal seam, Mary Lee/Blue Creek seam, and Jagger seam of Black Warrior Basin, Alabama, were determined from gas and water production history matching and production forecasting of vertical degasification wellbores. These properties were combined with isotherm and other important data to compute gas-in-place (GIP) and its change with time at borehole locations. Time-lapsed training images (TIs) of GIP and GIP difference corresponding to each coal and date were generated by using these point-wise data and Voronoi decomposition on the TI grid, which included faults as discontinuities for expansion of Voronoi regions. Filter-based multiple-point geostatistical simulations, which were preferred in this study due to anisotropies and discontinuities in the area, were used to predict time-lapsed GIP distributions within the study area. Performed simulations were used for mapping spatial time-lapsed methane quantities as well as their uncertainties within the study area. The systematic approach presented in this paper is the first time in literature that history matching, TIs of GIPs and filter simulations are used for degasification performance evaluation and for assessing GIP for mining safety. Results from this study showed that using production history matching of coalbed methane wells to determine time-lapsed reservoir data could be used to compute spatial GIP and representative GIP TIs generated through Voronoi decomposition

  12. SCAP-82, Single Scattering, Albedo Scattering, Point-Kernel Analysis in Complex Geometry

    International Nuclear Information System (INIS)

    Disney, R.K.; Vogtman, S.E.

    1987-01-01

    1 - Description of problem or function: SCAP solves for radiation transport in complex geometries using the single or albedo scatter point kernel method. The program is designed to calculate the neutron or gamma ray radiation level at detector points located within or outside a complex radiation scatter source geometry or a user specified discrete scattering volume. Geometry is describable by zones bounded by intersecting quadratic surfaces within an arbitrary maximum number of boundary surfaces per zone. Anisotropic point sources are describable as pointwise energy dependent distributions of polar angles on a meridian; isotropic point sources may also be specified. The attenuation function for gamma rays is an exponential function on the primary source leg and the scatter leg with a build- up factor approximation to account for multiple scatter on the scat- ter leg. The neutron attenuation function is an exponential function using neutron removal cross sections on the primary source leg and scatter leg. Line or volumetric sources can be represented as a distribution of isotropic point sources, with un-collided line-of-sight attenuation and buildup calculated between each source point and the detector point. 2 - Method of solution: A point kernel method using an anisotropic or isotropic point source representation is used, line-of-sight material attenuation and inverse square spatial attenuation between the source point and scatter points and the scatter points and detector point is employed. A direct summation of individual point source results is obtained. 3 - Restrictions on the complexity of the problem: - The SCAP program is written in complete flexible dimensioning so that no restrictions are imposed on the number of energy groups or geometric zones. The geometric zone description is restricted to zones defined by boundary surfaces defined by the general quadratic equation or one of its degenerate forms. The only restriction in the program is that the total

  13. Analysis method of beam pointing stability based on optical transmission matrix

    Science.gov (United States)

    Wang, Chuanchuan; Huang, PingXian; Li, Xiaotong; Cen, Zhaofen

    2016-10-01

    Quite a lot of factors will make effects on beam pointing stability of an optical system, Among them, the element tolerance is one of the most important and common factors. In some large laser systems, it will make final micro beams spot on the image plane deviate obviously. So it is essential for us to achieve effective and accurate analysis theoretically on element tolerance. In order to make the analysis of beam pointing stability convenient and theoretical, we consider transmission of a single chief ray rather than beams approximately to stand for the whole spot deviation. According to optical matrix, we also simplify this complex process of light transmission to multiplication of many matrices. So that we can set up element tolerance model, namely having mathematical expression to illustrate spot deviation in an optical system with element tolerance. In this way, we can realize quantitative analysis of beam pointing stability theoretically. In second half of the paper, we design an experiment to get the spot deviation in a multipass optical system caused by element tolerance, then we adjust the tolerance step by step and compare the results with the datum got from tolerance model, finally prove the correction of tolerance model successfully.

  14. Handbook of floating-point arithmetic

    CERN Document Server

    Muller, Jean-Michel; de Dinechin, Florent; Jeannerod, Claude-Pierre; Joldes, Mioara; Lefèvre, Vincent; Melquiond, Guillaume; Revol, Nathalie; Torres, Serge

    2018-01-01

    This handbook is a definitive guide to the effective use of modern floating-point arithmetic, which has considerably evolved, from the frequently inconsistent floating-point number systems of early computing to the recent IEEE 754-2008 standard. Most of computational mathematics depends on floating-point numbers, and understanding their various implementations will allow readers to develop programs specifically tailored for the standard’s technical features. Algorithms for floating-point arithmetic are presented throughout the book and illustrated where possible by example programs which show how these techniques appear in actual coding and design. The volume itself breaks its core topic into four parts: the basic concepts and history of floating-point arithmetic; methods of analyzing floating-point algorithms and optimizing them; implementations of IEEE 754-2008 in hardware and software; and useful extensions to the standard floating-point system, such as interval arithmetic, double- and triple-word arithm...

  15. Effective communication at the point of multiple sclerosis diagnosis.

    Science.gov (United States)

    Solari, Alessandra

    2014-04-01

    As a consequence of the current shortened diagnostic workup, people with multiple sclerosis (PwMS) are rapidly confronted with a disease of uncertain prognosis that requires complex treatment decisions. This paper reviews studies that have assessed the experiences of PwMS in the peri-diagnostic period and have evaluated the efficacy of interventions providing information at this critical moment. The studies found that the emotional burden on PwMS at diagnosis was high, and emphasised the need for careful monitoring and management of mood symptoms (chiefly anxiety). Information provision did not affect anxiety symptoms but improved patients' knowledge of their condition, the achievement of 'informed choice', and satisfaction with the diagnosis communication. It is vital to develop and implement information and decision aids for PwMS, but this is resource intensive, and international collaboration may be a way forward. The use of patient self-assessed outcome measures that appraise the quality of diagnosis communication is also important to allow health services to understand and meet the needs and preferences of PwMS.

  16. Quasi-experimental designs in practice-based research settings: design and implementation considerations.

    Science.gov (United States)

    Handley, Margaret A; Schillinger, Dean; Shiboski, Stephen

    2011-01-01

    Although randomized controlled trials are often a gold standard for determining intervention effects, in the area of practice-based research (PBR), there are many situations in which individual randomization is not possible. Alternative approaches to evaluating interventions have received increased attention, particularly those that can retain elements of randomization such that they can be considered "controlled" trials. Methodological design elements and practical implementation considerations for two quasi-experimental design approaches that have considerable promise in PBR settings--the stepped-wedge design, and a variant of this design, a wait-list cross-over design, are presented along with a case study from a recent PBR intervention for patients with diabetes. PBR-relevant design features include: creation of a cohort over time that collects control data but allows all participants (clusters or patients) to receive the intervention; staggered introduction of clusters; multiple data collection points; and one-way cross-over into the intervention arm. Practical considerations include: randomization versus stratification, training run in phases; and extended time period for overall study completion. Several design features of practice based research studies can be adapted to local circumstances yet retain elements to improve methodological rigor. Studies that utilize these methods, such as the stepped-wedge design and the wait-list cross-over design, can increase the evidence base for controlled studies conducted within the complex environment of PBR.

  17. [Orthogonal design method to optimize rehabilitation prescription of pulsed electric field at Jiaji (EX-B 2) points for spinal cord injury].

    Science.gov (United States)

    Zhang, Lifeng; Zhang, Hui; Wang, Lin; Liu, Yanyan; Sun, Xianyue; Li, Lingyan; Hou, Jing

    2015-01-01

    By using orthogonal design method to optimnize prescription of pulsed electric field at Jiaji (EX- B 2) points for spinal cord injury (SCI). Fifty six patients of SCI were selected, in which 36 cases were divided into orthogonal design trial and 20 cases were into clinical verification. With 36 patients who received orthogonal design trial, Frankel grading scale was used as observation index to screen optimal prescription of pulsed electric field. Pulse frequency (factor A) included low frequency (factor A(I), 10(2) Hz). moderate frequency (factor A(II), 10(4) Hz) and high frequency (factor A(III), 10(3) Hz); pulse amplitude (factor B) included 0-30 V (factor B ), 0-60 V (factor B(II)) and 0-90 V (factor B(III)); pulse width (factor C) included 0.1 ms (factor C(I)). 0.6 ms (factor C(II)) and 0.9 ms (factor C(III)); acupuncture time (factor D) included one month (DI), three months (D(II)) and five months (D(III)). Twenty patients were used for clinical efficacy observation and the effects of screened optimal pre scription of pulsed electric field at Jiaji (EX-B 2) points combined with regular rehabilitation training on spasm se- verity, score of sensory and motor functions, Barthel index and Frankel score were observed. (1) As results of orthogonal design trial, the optimal prescription was A(III) B(III), C(I), D(III), which were high frequency (10(3) Hz), 0-90 V of pulse amplitude, 0.4 ms of pulse width and 5 months of treatment time. (2) As results of 20 patient clinical verification, Ashworth score, tendon reflex and clonus were all significantly improved (Ppulsed electric field at Jiaji (EX-B 2) points for spinal cord injury is high frequency (10& Hz), 0-90 V of pulse amplitude, 0.4 ms of pulse width and 5 months of treatment time. The optimal prescription of pulsed electric field at Jiaji (EX-B 2) points combined with regular rehabilitation could obviously improve spasm severity, enhance senso- ry and motor functions, and ameliorate activity of daily life and

  18. An Optimal Design of Multiple Antenna Positions on Mobile Devices Based on Mutual Coupling Analysis

    Directory of Open Access Journals (Sweden)

    Peerapong Uthansakul

    2011-01-01

    Full Text Available The topic of practical implementation of multiple antenna systems for mobile communications has recently gained a lot of attention. Due to the area constraint on a mobile device, the problem of how to design such a system in order to achieve the best benefit is still a huge challenge. In this paper, genetic algorithm (GA is used to find the optimal antenna positions on a mobile device. Two cases of 3×3 and 4×4 MIMO systems are undertaken. The effect of mutual coupling based on Z-parameter is the main factor to determine the MIMO capacity concerning the objective function of GA search. The results confirm the success of the proposed method to design MIMO antenna positions on a mobile device. Moreover, this paper introduces the method to design the antenna positions for the condition of nondeterministic channel. The concern of channel variation has been included in the process of finding optimal MIMO antenna positions. The results suggest that the averaging position from all GA solutions according to all channel conditions provides the most acceptable benefit.

  19. Can multiple-choice questions simulate free-response questions?

    OpenAIRE

    Lin, Shih-Yin; Singh, Chandralekha

    2016-01-01

    We discuss a study to evaluate the extent to which free-response questions could be approximated by multiple-choice equivalents. Two carefully designed research-based multiple-choice questions were transformed into a free-response format and administered on the final exam in a calculus-based introductory physics course. The original multiple-choice questions were administered in another similar introductory physics course on final exam. Findings suggest that carefully designed multiple-choice...

  20. Multiple Monte Carlo Testing with Applications in Spatial Point Processes

    DEFF Research Database (Denmark)

    Mrkvička, Tomáš; Myllymäki, Mari; Hahn, Ute

    with a function as the test statistic, 3) several Monte Carlo tests with functions as test statistics. The rank test has correct (global) type I error in each case and it is accompanied with a p-value and with a graphical interpretation which shows which subtest or which distances of the used test function......(s) lead to the rejection at the prescribed significance level of the test. Examples of null hypothesis from point process and random set statistics are used to demonstrate the strength of the rank envelope test. The examples include goodness-of-fit test with several test functions, goodness-of-fit test...

  1. Multiple group membership and well-being

    DEFF Research Database (Denmark)

    Sønderlund, Anders L.; Morton, Thomas A.; Ryan, Michelle K.

    2017-01-01

    multiple group membership and well-being, but only for individuals high in SIC. This effect was mediated by perceived identity expression and access to social support. Study 2 (N = 104) also found that multiple group memberships indirectly contributed to well-being via perceived identity expression......A growing body of research points to the value of multiple group memberships for individual well-being. However, much of this work considers group memberships very broadly and in terms of number alone. We conducted two correlational studies exploring how the relationship between multiple group...... and social support, as well as identity compatibility and perceived social inclusion. But, in this study the relationship between multiple group memberships and well-being outcomes was moderated by the perceived value and visibility of group memberships to others. Specifically, possessing multiple, devalued...

  2. A Design of a Hybrid Non-Linear Control Algorithm

    Directory of Open Access Journals (Sweden)

    Farinaz Behrooz

    2017-11-01

    Full Text Available One of the high energy consuming devices in the buildings is the air-conditioning system. Designing a proper controller to consider the thermal comfort and simultaneously control the energy usage of the device will impact on the system energy efficiency and its performance. The aim of this study was to design a Multiple-Input and Multiple-Output (MIMO, non-linear, and intelligent controller on direct expansion air-conditioning system The control algorithm uses the Fuzzy Cognitive Map method as a main controller and the Generalized Predictive Control method is used for assigning the initial weights of the main controller. The results of the proposed controller shows that the controller was successfully designed and works in set point tracking and under disturbance rejection tests. The obtained results of the Generalized Predictive Control-Fuzzy Cognitive Map controller are compared with the previous MIMO Linear Quadratic Gaussian control design on the same direct expansion air-conditioning system under the same conditions. The comparative results indicate energy savings would be achieved with the proposed controller with long-term usage. Energy efficiency and thermal comfort conditions are achieved by the proposed controller.

  3. Modeling, simulation, and design of SAW grating filters

    Science.gov (United States)

    Schwelb, Otto; Adler, E. L.; Slaboszewicz, J. K.

    1990-05-01

    A systematic procedure for modeling, simulating, and designing SAW (surface acoustic wave) grating filters, taking losses into account, is described. Grating structures and IDTs (interdigital transducers) coupling to SAWs are defined by cascadable transmission-matrix building blocks. Driving point and transfer characteristics (immittances) of complex architectures consisting of gratings, transducers, and coupling networks are obtained by chain-multiplying building-block matrices. This modular approach to resonator filter analysis and design combines the elements of lossy filter synthesis with the transmission-matrix description of SAW components. A multipole filter design procedure based on a lumped-element-model approximation of one-pole two-port resonator building blocks is given and the range of validity of this model examined. The software for simulating the performance of SAW grating devices based on this matrix approach is described, and its performance, when linked to the design procedure to form a CAD/CAA (computer-aided design and analysis) multiple-filter design package, is illustrated with a resonator filter design example.

  4. JIGSAW: Acquisition, Display and Analysis system designed to collect data from Multiple Gamma-Ray detectors

    International Nuclear Information System (INIS)

    Haywood, S.E.; Bamford, G.J.; Rester, A.C.; Coldwell, R.L.

    1992-01-01

    In this paper, the authors report on work performed to date on JIGSAW - a self contained data acquisition, display and analysis system designed to collect data form multiple gamma-ray detectors. The data acquisition system utilizes commercially available VMEbus and NIM hardware modules and the VME exec real time operating system. A Unix based software package, written in ANSI standard C and with the XII graphics routines, allows the user to view the acquired spectra. Analysis of the histograms can be performed in background during the run with the ROBFIT suite of curve fitting routines

  5. The resilience of an operating point for a fusion power plant

    Energy Technology Data Exchange (ETDEWEB)

    Ward, David, E-mail: david.ward@ccfe.ac.uk; Kemp, Richard

    2015-10-15

    Highlights: • The need to control a power plant changes our view of the optimum design. • The need for control can be reduced by finding resilient design points. • It is important to include resilience and control in selecting design points. • Including these additional constraints reduces flexibility in choice of operating points. - Abstract: The operating point for fusion power plant design concepts is often determined by simultaneously satisfying the requirements of all of the main plant systems and finding an optimum solution, for instance the one with the lowest capital cost or cost of electricity. This static assessment takes no account of the sensitivity of that operating point to variations in key parameters and therefore includes no information about how difficult to adjust and control the chosen operating point may be. Control of the operation point is a large subject with much work still to be done, and is expected to play an increasing role in the future in choosing the optimum design point. Here we present results of two analyses: one relates to the ability to load follow, that is, to vary the power production in the light of varying demands for power from the electricity network; the other investigates in simple terms what choices we can make to improve the resilience of static operating points.

  6. Design and Delivery of Multiple Server-Side Computer Languages Course

    Science.gov (United States)

    Wang, Shouhong; Wang, Hai

    2011-01-01

    Given the emergence of service-oriented architecture, IS students need to be knowledgeable of multiple server-side computer programming languages to be able to meet the needs of the job market. This paper outlines the pedagogy of an innovative course of multiple server-side computer languages for the undergraduate IS majors. The paper discusses…

  7. Search for the QCD critical point at SPS energies

    CERN Document Server

    Anticic, T.; Barna, D.; Bartke, J.; Betev, L.; Bialkowska, H.; Blume, C.; Boimska, B.; Botje, M.; Bracinik, J.; Buncic, P.; Cerny, V.; Christakoglou, P.; Chung, P.; Chvala, O.; Cramer, J.G.; Csato, P.; Dinkelaker, P.; Eckardt, V.; Fodor, Z.; Foka, P.; Friese, V.; Gal, J.; Gazdzicki, M.; Genchev, V.; Gladysz, E.; Grebieszkow, K.; Hegyi, S.; Hohne, C.; Kadija, K.; Karev, A.; Kikola, D.; Kolesnikov, V.I.; Kornas, E.; Korus, R.; Kowalski, M.; Kreps, M.; Laszlo, A.; Lacey, R.; van Leeuwen, M.; Levai, P.; Litov, L.; Lungwitz, B.; Makariev, M.; Malakhov, A.I.; Mateev, M.; Melkumov, G.L.; Mischke, A.; Mitrovski, M.; Mrowczynski, St.; Palla, G.; Panagiotou, A.D.; Petridis, A.; Peryt, W.; Pikna, M.; Pluta, J.; Prindle, D.; Puhlhofer, F.; Renfordt, R.; Roland, C.; Roland, G.; Rybczynski, M.; Rybicki, A.; Sandoval, A.; Schmitz, N.; Schuster, T.; Seyboth, P.; Sikler, F.; Sitar, B.; Skrzypczak, E.; Slodkowski, M.; Stefanek, G.; Stock, R.; Strabel, C.; Strobele, H.; Susa, T.; Szentpetery, I.; Sziklai, J.; Szuba, M.; Szymanski, P.; Trubnikov, V.; Utvic, M.; Varga, D.; Vassiliou, M.; Veres, G.I.; Vesztergombi, G.; Vranic, D.; Wlodarczyk, Z.; Wojtaszek-Szwarc, A.; Yoo, I.K.; Abgrall, N.; Aduszkiewicz, A.; Andrieu, B.; Anticic, T.; Antoniou, N.; Argyriades, J.; Asryan, A.G.; Blondel, A.; Blumer, J.; Boldizsar, L.; Bravar, A.; Brzychczyk, J.; Bubak, A.; Bunyatov, S.A.; Choi, K.-U.; Chung, P.; Cleymans, J.; Derkach, D.A.; Diakonos, F.; Dominik, W.; Dumarchez, J.; Engel, R.; Ereditato, A.; Feofilov, G.A.; Ferrero, A.; Gazdzicki, M.; Golubeva, M.; Grzeszczuk, A.; Guber, F.; Hasegawa, T.; Haungs, A.; Igolkin, S.; Ivanov, A.S.; Ivashkin, A.; Katrynska, N.; Kielczewska, D.; Kisiel, J.; Kobayashi, T.; Kolev, D.; Kolevatov, R.S.; Kondratiev, V.P.; Kowalski, S.; Kurepin, A.; Lacey, R.; Lyubushkin, V.V.; Majka, Z.; Marchionni, A.; Marcinek, A.; Maris, I.; Matveev, V.; Meregaglia, A.; Messina, M.; Mijakowski, P.; Montaruli, T.; Murphy, S.; Nakadaira, T.; Naumenko, P.A.; Nikolic, V.; Nishikawa, K.; Palczewski, T.; Planeta, R.; Popov, B.A.; Posiadala, M.; Przewlocki, P.; Rauch, W.; Ravonel, M.; Rohrich, D.; Rondio, E.; Rossi, B.; Roth, M.; Rubbia, A.; Sadovsky, A.; Sakashita, K.; Sekiguchi, T.; Seyboth, P.; Shibata, M.; Sissakian, A.N.; Sorin, A.S.; Staszel, P.; Stepaniak, J.; Strabel, C.; Stroebele, H.; Tada, M.; Taranenko, A.; Tsenov, R.; Ulrich, R.; Unger, M.; Vechernin, V.V.; Zipper, W.

    2009-01-01

    Lattice QCD calculations locate the QCD critical point at energies accessible at the CERN Super Proton Synchrotron (SPS). We present average transverse momentum and multiplicity fluctuations, as well as baryon and anti-baryon transverse mass spectra which are expected to be sensitive to effects of the critical point. The future CP search strategy of the NA61/SHINE experiment at the SPS is also discussed.

  8. Design and Comparison of Cascaded H-Bridge, Modular Multilevel Converter, and 5-L Active Neutral Point Clamped Topologies for Motor Drive Applications

    Energy Technology Data Exchange (ETDEWEB)

    Marzoughi, Alinaghi [Virginia Tech, Blacksburg, VA (United States). Center for Power Electronics Systems; Burgos, Rolando [Virginia Tech, Blacksburg, VA (United States). Bradley Dept. of Electrical and Computer Engineering; Boroyevich, Dushan [Virginia Tech, Blacksburg, VA (United States). Bradley Dept. of Electrical and Computer Engineering; Xue, Yaosuo [Siemens Corporate Research, Princeton, NJ (United States). Power Electronics Dept.

    2018-03-01

    This paper presents the design procedure and comparison of converters currently used in medium-voltage high-power motor drive applications. For this purpose, the cascaded H-bridge (CHB), modular multilevel converter (MMC), and five-level active neutral point clamped (5-L ANPC) topologies are targeted. The design is performed using 1.7-kV insulated gate bipolar transistors (IGBTs) for CHB and MMC converters, and utilizing 3.3- and 4.5-kV IGBTs for 5-L ANPC topology as normally done in industry. The comparison is done between the designed converter topologies at three different voltage levels (4.16, 6.9, and 13.8 kV, with only the first two voltage levels in case of the 5-L ANPC) and two different power levels (3 and 5 MVA), in order to elucidate the dependence of different parameters on voltage and power rating. Finally, the comparison is done from several points of view such as efficiency, capacitive energy storage, semiconductor utilization, parts count (for measure of reliability), and power density.

  9. On the Required Number of Antennas in a Point-to-Point Large-but-Finite MIMO System: Outage-Limited Scenario

    KAUST Repository

    Makki, Behrooz

    2016-03-22

    This paper investigates the performance of the point-To-point multiple-input-multiple-output (MIMO) systems in the presence of a large but finite numbers of antennas at the transmitters and/or receivers. Considering the cases with and without hybrid automatic repeat request (HARQ) feedback, we determine the minimum numbers of the transmit/receive antennas, which are required to satisfy different outage probability constraints. Our results are obtained for different fading conditions and the effect of the power amplifiers efficiency/feedback error probability on the performance of the MIMO-HARQ systems is analyzed. Then, we use some recent results on the achievable rates of finite block-length codes, to analyze the effect of the codewords lengths on the system performance. Moreover, we derive closed-form expressions for the asymptotic performance of the MIMO-HARQ systems when the number of antennas increases. Our analytical and numerical results show that different outage requirements can be satisfied with relatively few transmit/receive antennas. © 1972-2012 IEEE.

  10. Word Length Selection Method for Controller Implementation on FPGAs Using the VHDL-2008 Fixed-Point and Floating-Point Packages

    Directory of Open Access Journals (Sweden)

    Urriza I

    2010-01-01

    Full Text Available Abstract This paper presents a word length selection method for the implementation of digital controllers in both fixed-point and floating-point hardware on FPGAs. This method uses the new types defined in the VHDL-2008 fixed-point and floating-point packages. These packages allow customizing the word length of fixed and floating point representations and shorten the design cycle simplifying the design of arithmetic operations. The method performs bit-true simulations in order to determine the word length to represent the constant coefficients and the internal signals of the digital controller while maintaining the control system specifications. A mixed-signal simulation tool is used to simulate the closed loop system as a whole in order to analyze the impact of the quantization effects and loop delays on the control system performance. The method is applied to implement a digital controller for a switching power converter. The digital circuit is implemented on an FPGA, and the simulations are experimentally verified.

  11. Using the Direct Sampling Multiple-Point Geostatistical Method for Filling Gaps in Landsat 7 ETM+ SLC-off Imagery

    KAUST Repository

    Yin, Gaohong

    2016-05-01

    Since the failure of the Scan Line Corrector (SLC) instrument on Landsat 7, observable gaps occur in the acquired Landsat 7 imagery, impacting the spatial continuity of observed imagery. Due to the highly geometric and radiometric accuracy provided by Landsat 7, a number of approaches have been proposed to fill the gaps. However, all proposed approaches have evident constraints for universal application. The main issues in gap-filling are an inability to describe the continuity features such as meandering streams or roads, or maintaining the shape of small objects when filling gaps in heterogeneous areas. The aim of the study is to validate the feasibility of using the Direct Sampling multiple-point geostatistical method, which has been shown to reconstruct complicated geological structures satisfactorily, to fill Landsat 7 gaps. The Direct Sampling method uses a conditional stochastic resampling of known locations within a target image to fill gaps and can generate multiple reconstructions for one simulation case. The Direct Sampling method was examined across a range of land cover types including deserts, sparse rural areas, dense farmlands, urban areas, braided rivers and coastal areas to demonstrate its capacity to recover gaps accurately for various land cover types. The prediction accuracy of the Direct Sampling method was also compared with other gap-filling approaches, which have been previously demonstrated to offer satisfactory results, under both homogeneous area and heterogeneous area situations. Studies have shown that the Direct Sampling method provides sufficiently accurate prediction results for a variety of land cover types from homogeneous areas to heterogeneous land cover types. Likewise, it exhibits superior performances when used to fill gaps in heterogeneous land cover types without input image or with an input image that is temporally far from the target image in comparison with other gap-filling approaches.

  12. System and method for design and optimization of grid connected photovoltaic power plant with multiple photovoltaic module technologies

    Science.gov (United States)

    Thomas, Bex George; Elasser, Ahmed; Bollapragada, Srinivas; Galbraith, Anthony William; Agamy, Mohammed; Garifullin, Maxim Valeryevich

    2016-03-29

    A system and method of using one or more DC-DC/DC-AC converters and/or alternative devices allows strings of multiple module technologies to coexist within the same PV power plant. A computing (optimization) framework estimates the percentage allocation of PV power plant capacity to selected PV module technologies. The framework and its supporting components considers irradiation, temperature, spectral profiles, cost and other practical constraints to achieve the lowest levelized cost of electricity, maximum output and minimum system cost. The system and method can function using any device enabling distributed maximum power point tracking at the module, string or combiner level.

  13. Optimal Point-to-Point Trajectory Tracking of Redundant Manipulators using Generalized Pattern Search

    Directory of Open Access Journals (Sweden)

    Thi Rein Myo

    2008-11-01

    Full Text Available Optimal point-to-point trajectory planning for planar redundant manipulator is considered in this study. The main objective is to minimize the sum of the position error of the end-effector at each intermediate point along the trajectory so that the end-effector can track the prescribed trajectory accurately. An algorithm combining Genetic Algorithm and Pattern Search as a Generalized Pattern Search GPS is introduced to design the optimal trajectory. To verify the proposed algorithm, simulations for a 3-D-O-F planar manipulator with different end-effector trajectories have been carried out. A comparison between the Genetic Algorithm and the Generalized Pattern Search shows that The GPS gives excellent tracking performance.

  14. Limits in point to point resolution of MOS based pixels detector arrays

    Science.gov (United States)

    Fourches, N.; Desforge, D.; Kebbiri, M.; Kumar, V.; Serruys, Y.; Gutierrez, G.; Leprêtre, F.; Jomard, F.

    2018-01-01

    In high energy physics point-to-point resolution is a key prerequisite for particle detector pixel arrays. Current and future experiments require the development of inner-detectors able to resolve the tracks of particles down to the micron range. Present-day technologies, although not fully implemented in actual detectors, can reach a 5-μm limit, this limit being based on statistical measurements, with a pixel-pitch in the 10 μm range. This paper is devoted to the evaluation of the building blocks for use in pixel arrays enabling accurate tracking of charged particles. Basing us on simulations we will make here a quantitative evaluation of the physical and technological limits in pixel size. Attempts to design small pixels based on SOI technology will be briefly recalled here. A design based on CMOS compatible technologies that allow a reduction of the pixel size below the micrometer is introduced here. Its physical principle relies on a buried carrier-localizing collecting gate. The fabrication process needed by this pixel design can be based on existing process steps used in silicon microelectronics. The pixel characteristics will be discussed as well as the design of pixel arrays. The existing bottlenecks and how to overcome them will be discussed in the light of recent ion implantation and material characterization experiments.

  15. Design and implementation of a microcontroller-based maximum power point tracking fuzzy solar-charge controller

    Energy Technology Data Exchange (ETDEWEB)

    Qazalbash, A.A.; Iqbal, T.; Shafiq, M.Z. [National Univ. of Sciences and Technology, Rawalpindi (Pakistan). Dept. of Electrical Engineering

    2007-07-01

    Photovoltaic (PV) solar arrays are particularly useful for electrical power generation in remote, off-grid areas in developing countries. However, PV arrays offer a small power to area ratio, resulting in the need for more PV arrays which increases the cost of the system. In order to improve the profitability of PV arrays, the power extraction from available PV array systems must be maximized. This paper presented an analysis, modeling and implementation of an efficient solar charge controller. It was shown that the maximum power of a photovoltaic system depends largely on temperature and insolation. A perturb and observe algorithm was used for maximum power point tracking (MPPT). MPPT maximizes the efficiency of a solar PV system. A solar charge controller determines the optimal values of output current and voltage of converters to maximize power output for battery charging. In order to improve performance and implement the perturb and observe algorithm, the authors designed a fuzzy rule-based system in which a solar charge controller worked with a PWM controlled DC-DC converter for battery charging. The system was implemented on a low-cost PIC microcontroller. Results were better than conventional techniques in power efficiency. Swift maximum power point tracking was obtained. 13 refs., 1 tab., 11 figs.

  16. Schroedinger operators with point interactions and short range expansions

    International Nuclear Information System (INIS)

    Albeverio, S.; Hoeegh-Krohn, R.; Oslo Univ.

    1984-01-01

    We give a survey of recent results concerning Schroedinger operators with point interactions in R 3 . In the case where the point interactions are located at a discrete set of points we discuss results about the resolvent, the spectrum, the resonances and the scattering quantities. We also discuss the approximation of point interactions by short range local potentials (short range or low energy expansions) and the one electron model of a 3-dimensional crystal. Moreover we discuss Schroedinger operators with Coulomb plus point interactions, with applications to the determination of scattering lengths and of level shifts in mesic atoms. Further applications to the multiple well problem, to multiparticle systems, to crystals with random impurities, to polymers and quantum fields are also briefly discussed. (orig.)

  17. Fluoride Salt-Cooled High-Temperature Demonstration Reactor Point Design

    Energy Technology Data Exchange (ETDEWEB)

    Qualls, A. L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Brown, Nicholas R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Betzler, Benjamin R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Carbajo, Juan [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hale, Richard Edward [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Harrison, Thomas J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Powers, Jeffrey J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Robb, Kevin R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Terrell, Jerry W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wysocki, Aaron J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-02-01

    The fluoride salt-cooled high-temperature reactor (FHR) demonstration reactor (DR) is a concept for a salt-cooled reactor with 100 megawatts of thermal output (MWt). It would use tristructural-isotropic (TRISO) particle fuel within prismatic graphite blocks. FLiBe (2 LiF-BeF2) is the reference primary coolant. The FHR DR is designed to be small, simple, and affordable. Development of the FHR DR is a necessary intermediate step to enable near-term commercial FHRs. Lower risk technologies are purposely included in the initial FHR DR design to ensure that the reactor can be built, licensed, and operated within an acceptable budget and schedule. These technologies include TRISO particle fuel, replaceable core structural material, the use of that same material for the primary and intermediate loops, and tube-and-shell primary-to-intermediate heat exchangers. Several preconceptual and conceptual design efforts that have been conducted on FHR concepts bear a significant influence on the FHR DR design. Specific designs include the Oak Ridge National Laboratory (ORNL) advanced high-temperature reactor (AHTR) with 3400/1500 MWt/megawatts of electric output (MWe), as well as a 125 MWt small modular AHTR (SmAHTR) from ORNL. Other important examples are the Mk1 pebble bed FHR (PB-FHR) concept from the University of California, Berkeley (UCB), and an FHR test reactor design developed at the Massachusetts Institute of Technology (MIT). The MIT FHR test reactor is based on a prismatic fuel platform and is directly relevant to the present FHR DR design effort. These FHR concepts are based on reasonable assumptions for credible commercial prototypes. The FHR DR concept also directly benefits from the operating experience of the Molten Salt Reactor Experiment (MSRE), as well as the detailed design efforts for a large molten salt reactor concept and its breeder variant, the Molten Salt Breeder Reactor. The FHR DR technology is most representative of the 3400 MWt AHTR

  18. A design of a wavelength-hopping time-spreading incoherent optical code division multiple access system

    International Nuclear Information System (INIS)

    Glesk, I.; Baby, V.

    2005-01-01

    We present the architecture and code design for a highly scalable, 2.5 Gb/s per user optical code division multiple access (OCDMA) system. The system is scalable to 100 potential and more than 10 simultaneous users, each with a bit error rate (BER) of less than 10 -9 . The system architecture uses a fast wavelength-hopping, time-spreading codes. Unlike frequency and phase sensitive coherent OCDMA systems, this architecture utilizes standard on off keyed optical pulses allocated in the time and wavelength dimensions. This incoherent OCDMA approach is compatible with existing WDM optical networks and utilizes off the shelf components. We discuss the novel optical subsystem design for encoders and decoders that enable the realization of a highly scalable incoherent OCDMA system with rapid reconfigurability. A detailed analysis of the scalability of the two dimensional code is presented and select network deployment architectures for OCDMA are discussed (Authors)

  19. BetterPoints: Motivating behaviour change using technology-driven incentivisation

    Directory of Open Access Journals (Sweden)

    Anne Lancaster

    2015-10-01

    The BetterPoints system is unique in it’s flexibility and ability to draw on multiple behaviour change models to create high quality interventions. Early findings from existing programmes being implemented for Local Authorities in the UK suggest that BetterPoints can demonstrate real-world behaviour change. We would like to work with academic partners to further investigate these real-world changes in behaviour and establish a robust evidence base.

  20. Time-lapse analysis of methane quantity in Mary Lee group of coal seams using filter-based multiple-point geostatistical simulation

    Science.gov (United States)

    Karacan, C. Özgen; Olea, Ricardo A.

    2013-01-01

    Coal seam degasification and its success are important for controlling methane, and thus for the health and safety of coal miners. During the course of degasification, properties of coal seams change. Thus, the changes in coal reservoir conditions and in-place gas content as well as methane emission potential into mines should be evaluated by examining time-dependent changes and the presence of major heterogeneities and geological discontinuities in the field. In this work, time-lapsed reservoir and fluid storage properties of the New Castle coal seam, Mary Lee/Blue Creek seam, and Jagger seam of Black Warrior Basin, Alabama, were determined from gas and water production history matching and production forecasting of vertical degasification wellbores. These properties were combined with isotherm and other important data to compute gas-in-place (GIP) and its change with time at borehole locations. Time-lapsed training images (TIs) of GIP and GIP difference corresponding to each coal and date were generated by using these point-wise data and Voronoi decomposition on the TI grid, which included faults as discontinuities for expansion of Voronoi regions. Filter-based multiple-point geostatistical simulations, which were preferred in this study due to anisotropies and discontinuities in the area, were used to predict time-lapsed GIP distributions within the study area. Performed simulations were used for mapping spatial time-lapsed methane quantities as well as their uncertainties within the study area.

  1. Spatial Evaluation of Multiple Benefits to Encourage Multi-Functional Design of Sustainable Drainage in Blue-Green Cities

    Directory of Open Access Journals (Sweden)

    Richard Fenner

    2017-12-01

    Full Text Available Urban drainage systems that incorporate elements of green infrastructure (SuDS/GI are central features in Blue-Green and Sponge Cities. Such approaches provide effective control of stormwater management whilst generating a range of other benefits. However these benefits often occur coincidentally and are not developed or maximised in the original design. Of all the benefits that may accrue, the relevant dominant benefits relating to specific locations and socio-environmental circumstances need to be established, so that flood management functions can be co-designed with these wider benefits to ensure both are achieved during system operation. The paper reviews a number of tools which can evaluate the multiple benefits of SuDS/GI interventions in a variety of ways and introduces new concepts of benefit intensity and benefit profile. Examples of how these concepts can be applied is provided in a case study of proposed SuDS/GI assets in the central area of Newcastle; UK. Ways in which SuDS/GI features can be actively extended to develop desired relevant dominant benefits are discussed; e.g., by (i careful consideration of tree and vegetation planting to trap air pollution; (ii extending linear SuDS systems such as swales to enhance urban connectivity of green space; and (iii managing green roofs for the effective attenuation of noise or carbon sequestration. The paper concludes that more pro-active development of multiple benefits is possible through careful co-design to achieve the full extent of urban enhancement SuDS/GI schemes can offer.

  2. The cause multiplicity and the multiple cause style of adverse events in Japanese nuclear power plants

    International Nuclear Information System (INIS)

    Miyazaki, Takamasa

    2008-01-01

    An adverse event in a nuclear power plant occurs due to either one cause or multiple causes. To consider ways of preventing adverse events, it is useful to clarify whether events are caused by single or multiple causes. In this study, the multiple causes is expressed using the cause multiplicity and the multiple cause style. Classified causes of adverse events in Japanese nuclear power plants were analyzed, with the following results: the cause multiplicity of serious adverse events is higher than that of minor adverse events, and the multiple cause style can be expressed by combining two styles: series type and parallel type. Also, for a multiple cause event, a new method of displaying the event is presented as a cause-chain chart where the cause items are arranged in a sequential way and are connected considering the mutual relations among the causes. This new display method shows the whole flow of issues concerning the event more simply than the conventional display method of the chain of phenomena, and would be useful for considering the terminating point of the chain of causes. (author)

  3. Wide Field Infrared Survey Telescope [WFIRST]: telescope design and simulated performance

    Science.gov (United States)

    Goullioud, R.; Content, D. A.; Kuan, G. M.; Moore, J. D.; Chang, Z.; Sunada, E. T.; Villalvazo, J.; Hawk, J. P.; Armani, N. V.; Johnson, E. L.; Powell, C. A.

    2012-09-01

    The Wide Field Infrared Survey Telescope (WFIRST) mission concept was ranked first in new space astrophysics missions by the Astro2010 Decadal Survey, incorporating the Joint Dark Energy Mission payload concept and multiple science white papers. This mission is based on a space telescope at L2 studying exoplanets [via gravitational microlensing], probing dark energy, and surveying the near infrared sky. Since the release of the Astro2010 Decadal Survey, the team has been working with the WFIRST Science Definition Team to refine mission and payload concepts. We present the current interim reference mission point design of the payload, based on the use of a 1.3m unobscured aperture three mirror anastigmat form, with focal imaging and slit-less spectroscopy science channels. We also present the first results of Structural/Thermal/Optical performance modeling of the telescope point design.

  4. Stochastic production phase design for an open pit mining complex with multiple processing streams

    Science.gov (United States)

    Asad, Mohammad Waqar Ali; Dimitrakopoulos, Roussos; van Eldert, Jeroen

    2014-08-01

    In a mining complex, the mine is a source of supply of valuable material (ore) to a number of processes that convert the raw ore to a saleable product or a metal concentrate for production of the refined metal. In this context, expected variation in metal content throughout the extent of the orebody defines the inherent uncertainty in the supply of ore, which impacts the subsequent ore and metal production targets. Traditional optimization methods for designing production phases and ultimate pit limit of an open pit mine not only ignore the uncertainty in metal content, but, in addition, commonly assume that the mine delivers ore to a single processing facility. A stochastic network flow approach is proposed that jointly integrates uncertainty in supply of ore and multiple ore destinations into the development of production phase design and ultimate pit limit. An application at a copper mine demonstrates the intricacies of the new approach. The case study shows a 14% higher discounted cash flow when compared to the traditional approach.

  5. Simple Approaches to Minimally-Instrumented, Microfluidic-Based Point-of-Care Nucleic Acid Amplification Tests

    Science.gov (United States)

    Mauk, Michael G.; Song, Jinzhao; Liu, Changchun; Bau, Haim H.

    2018-01-01

    Designs and applications of microfluidics-based devices for molecular diagnostics (Nucleic Acid Amplification Tests, NAATs) in infectious disease testing are reviewed, with emphasis on minimally instrumented, point-of-care (POC) tests for resource-limited settings. Microfluidic cartridges (‘chips’) that combine solid-phase nucleic acid extraction; isothermal enzymatic nucleic acid amplification; pre-stored, paraffin-encapsulated lyophilized reagents; and real-time or endpoint optical detection are described. These chips can be used with a companion module for separating plasma from blood through a combined sedimentation-filtration effect. Three reporter types: Fluorescence, colorimetric dyes, and bioluminescence; and a new paradigm for end-point detection based on a diffusion-reaction column are compared. Multiplexing (parallel amplification and detection of multiple targets) is demonstrated. Low-cost detection and added functionality (data analysis, control, communication) can be realized using a cellphone platform with the chip. Some related and similar-purposed approaches by others are surveyed. PMID:29495424

  6. Simple Approaches to Minimally-Instrumented, Microfluidic-Based Point-of-Care Nucleic Acid Amplification Tests

    Directory of Open Access Journals (Sweden)

    Michael G. Mauk

    2018-02-01

    Full Text Available Designs and applications of microfluidics-based devices for molecular diagnostics (Nucleic Acid Amplification Tests, NAATs in infectious disease testing are reviewed, with emphasis on minimally instrumented, point-of-care (POC tests for resource-limited settings. Microfluidic cartridges (‘chips’ that combine solid-phase nucleic acid extraction; isothermal enzymatic nucleic acid amplification; pre-stored, paraffin-encapsulated lyophilized reagents; and real-time or endpoint optical detection are described. These chips can be used with a companion module for separating plasma from blood through a combined sedimentation-filtration effect. Three reporter types: Fluorescence, colorimetric dyes, and bioluminescence; and a new paradigm for end-point detection based on a diffusion-reaction column are compared. Multiplexing (parallel amplification and detection of multiple targets is demonstrated. Low-cost detection and added functionality (data analysis, control, communication can be realized using a cellphone platform with the chip. Some related and similar-purposed approaches by others are surveyed.

  7. Multiple-bunch-length operating mode design for a storage ring using hybrid low alpha and harmonic cavity method

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Weiwei, E-mail: gaomqr@mail.ustc.edu.cn [College of Mathematics and Physics, Fujian University of Technology, Fuzhou 350118 (China); Wang, Lin; Li, Heting [National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230029 (China)

    2017-03-11

    In this paper we design a simultaneous three bunch length operating mode at the HLS-II (Hefei Light Source II) storage ring by installing two harmonic cavities and minimizing the momentum compaction factor. The short bunches (2.6 mm) presented in this work will meet the requirement of coherent millimeter-wave and sub-THz radiation experiments, while the long bunches (20 mm) will efficiently increase the total beam current. Therefore, this multiple-bunch-length operating mode allows present synchrotron users and coherent millimeter-wave users (or sub THz users) to carry out their experiments simultaneously. Since the relatively low energy characteristic of HLS-II we achieve the multiple-bunch-length operating mode without multicell superconducting RF cavities, which is technically feasible.

  8. Symmetric caging formation for convex polygonal object transportation by multiple mobile robots based on fuzzy sliding mode control.

    Science.gov (United States)

    Dai, Yanyan; Kim, YoonGu; Wee, SungGil; Lee, DongHa; Lee, SukGyu

    2016-01-01

    In this paper, the problem of object caging and transporting is considered for multiple mobile robots. With the consideration of minimizing the number of robots and decreasing the rotation of the object, the proper points are calculated and assigned to the multiple mobile robots to allow them to form a symmetric caging formation. The caging formation guarantees that all of the Euclidean distances between any two adjacent robots are smaller than the minimal width of the polygonal object so that the object cannot escape. In order to avoid collision among robots, the parameter of the robots radius is utilized to design the caging formation, and the A⁎ algorithm is used so that mobile robots can move to the proper points. In order to avoid obstacles, the robots and the object are regarded as a rigid body to apply artificial potential field method. The fuzzy sliding mode control method is applied for tracking control of the nonholonomic mobile robots. Finally, the simulation and experimental results show that multiple mobile robots are able to cage and transport the polygonal object to the goal position, avoiding obstacles. Copyright © 2015 ISA. Published by Elsevier Ltd. All rights reserved.

  9. The QCD Critical Point and Related Observables

    Energy Technology Data Exchange (ETDEWEB)

    Nahrgang, Marlene

    2016-12-15

    The search for the critical point of QCD in heavy-ion collision experiments has sparked enormous interest with the completion of phase I of the RHIC beam energy scan. Here, I review the basics of the thermodynamics of the QCD phase transition and its implications for experimental multiplicity fluctuations in heavy-ion collisions. Several sources of noncritical fluctuations impact the observables and need to be understood in addition to the critical phenomena. Recent progress has been made in dynamical modeling of critical fluctuations, which ultimately is indispensable to understand potential signals of the QCD critical point in heavy-ion collision.

  10. Interest point detection for hyperspectral imagery

    Science.gov (United States)

    Dorado-Muñoz, Leidy P.; Vélez-Reyes, Miguel; Roysam, Badrinath; Mukherjee, Amit

    2009-05-01

    This paper presents an algorithm for automated extraction of interest points (IPs)in multispectral and hyperspectral images. Interest points are features of the image that capture information from its neighbours and they are distinctive and stable under transformations such as translation and rotation. Interest-point operators for monochromatic images were proposed more than a decade ago and have since been studied extensively. IPs have been applied to diverse problems in computer vision, including image matching, recognition, registration, 3D reconstruction, change detection, and content-based image retrieval. Interest points are helpful in data reduction, and reduce the computational burden of various algorithms (like registration, object detection, 3D reconstruction etc) by replacing an exhaustive search over the entire image domain by a probe into a concise set of highly informative points. An interest operator seeks out points in an image that are structurally distinct, invariant to imaging conditions, stable under geometric transformation, and interpretable which are good candidates for interest points. Our approach extends ideas from Lowe's keypoint operator that uses local extrema of Difference of Gaussian (DoG) operator at multiple scales to detect interest point in gray level images. The proposed approach extends Lowe's method by direct conversion of scalar operations such as scale-space generation, and extreme point detection into operations that take the vector nature of the image into consideration. Experimental results with RGB and hyperspectral images which demonstrate the potential of the method for this application and the potential improvements of a fully vectorial approach over band-by-band approaches described in the literature.

  11. Design and Implementation of Photovoltaic Maximum Power Point Tracking Controller

    Directory of Open Access Journals (Sweden)

    Fawaz S. Abdullah

    2018-03-01

    Full Text Available  The power supplied by any solar array depends upon the environmental conditions as weather conditions (temperature and radiation intensity and the incident angle of the radiant source. The work aims to study the maximum power tracking schemes that used to compare the system performance without and with different types of controllers. The maximum power points of the solar panel under test studied and compared with two controller's types.  The first controller is the proportional- integral - derivative controller type and the second is the perturbation and observation algorithm controller. The associated converter system is a microcontroller based type, whereas the results studied and compared of greatest power point of the Photovoltaic panels under the different two controllers. The experimental tests results compared with simulation results to verify accurate performance.

  12. Multiple Stages 2

    DEFF Research Database (Denmark)

    Andreasen, John

    Multiple stages 2: theatrical futures, set design, community plays, cultural capitals, democracy & drama, WWII dramas, performance on adoption, promenade about emigration, qualities in political theatre, performance analysis, dramaturgical education, Toulmin Variations...

  13. Damping Improvement of Multiple Damping Controllers by Using Optimal Coordinated Design Based on PSS and FACTS-POD in a Multi-Machine Power System

    Directory of Open Access Journals (Sweden)

    Ali Nasser Hussain

    2016-09-01

    Full Text Available The aim of this study is to present a comprehensive comparison and assessment of the damping function improvement of power system oscillation for the multiple damping controllers using the simultaneously coordinated design based on Power System Stabilizer (PSS and Flexible AC Transmission System (FACTS devices. FACTS devices can help in the enhancing the stability of the power system by adding supplementary damping controller to the control channel of the FACTS input to implement the task of Power Oscillation Damping (FACT POD controller. Simultaneous coordination can be performed in different ways. First, the dual coordinated designs between PSS and FACTS POD controller or between different FACTS POD controllers are arranged in a multiple FACTS devices without PSS. Second, the simultaneous coordination has been extended to triple coordinated design among PSS and different FACTS POD controllers. The parameters of the damping controllers have been tuned in the individual controllers and coordinated designs by using a Chaotic Particle Swarm Optimization (CPSO algorithm that optimized the given eigenvalue-based objective function. The simulation results for a multi-machine power system show that the dual coordinated design provide satisfactory damping performance over the individual control responses. Furthermore, the triple coordinated design has been shown to be more effective in damping oscillations than the dual damping controllers.

  14. Somatosensory impairment and its association with balance limitation in people with multiple sclerosis.

    Science.gov (United States)

    Jamali, Akram; Sadeghi-Demneh, Ebrahim; Fereshtenajad, Niloufar; Hillier, Susan

    2017-09-01

    Somatosensory impairments are common in multiple sclerosis. However, little data are available to characterize the nature and frequency of these problems in people with multiple sclerosis. To investigate the frequency of somatosensory impairments and identify any association with balance limitations in people with multiple sclerosis. The design was a prospective cross-sectional study, involving 82 people with multiple sclerosis and 30 healthy controls. Tactile and proprioceptive sensory acuity were measured using the Rivermead Assessment of Somatosensory Performance. Vibration duration was assessed using a tuning fork. Duration for the Timed Up and Go Test and reaching distance of the Functional Reach Test were measured to assess balance limitations. The normative range of sensory modalities was defined using cut-off points in the healthy participants. The multivariate linear regression was used to identify the significant predictors of balance in people with multiple sclerosis. Proprioceptive impairments (66.7%) were more common than tactile (60.8%) and vibration impairments (44.9%). Somatosensory impairments were more frequent in the lower limb (78.2%) than the upper limb (64.1%). All sensory modalities were significantly associated with the Timed Up and Go and Functional Reach tests (plimitation. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Design of an image encryption scheme based on a multiple chaotic map

    Science.gov (United States)

    Tong, Xiao-Jun

    2013-07-01

    In order to solve the problem that chaos is degenerated in limited computer precision and Cat map is the small key space, this paper presents a chaotic map based on topological conjugacy and the chaotic characteristics are proved by Devaney definition. In order to produce a large key space, a Cat map named block Cat map is also designed for permutation process based on multiple-dimensional chaotic maps. The image encryption algorithm is based on permutation-substitution, and each key is controlled by different chaotic maps. The entropy analysis, differential analysis, weak-keys analysis, statistical analysis, cipher random analysis, and cipher sensibility analysis depending on key and plaintext are introduced to test the security of the new image encryption scheme. Through the comparison to the proposed scheme with AES, DES and Logistic encryption methods, we come to the conclusion that the image encryption method solves the problem of low precision of one dimensional chaotic function and has higher speed and higher security.

  16. FB-line neutron multiplicity counter operation manual

    International Nuclear Information System (INIS)

    Langner, D.G.; Sweet, M.R.; Salazar, S.D.; Kroncke, K.E.

    1998-01-01

    This manual describes the design features, performance, and operating characteristics for the FB-Line Neutron Multiplicity Counter (FBLNMC). The FBLNMC counts neutron multiplicities to quantitatively assay plutonium in many forms, including impure scrap and waste. Monte Carlo neutronic calculations were used to design the high-efficiency (57%) detector that has 113 3 H tubes in a high-density polyethylene body. The new derandomizer circuit is included in the design to reduce deadtime. The FBLNMC can be applied to plutonium masses in the range from a few tens of grams to 5 kg; both conventional coincidence counting and multiplicity counting can be used as appropriate. This manual gives the performance data and preliminary calibration parameters for the FBLNMC

  17. Radiative symmetry breaking from interacting UV fixed points

    DEFF Research Database (Denmark)

    Abel, Steven; Sannino, Francesco

    2017-01-01

    It is shown that the addition of positive mass-squared terms to asymptotically safe gauge-Yukawa theories with perturbative UV fixed points leads to calculable radiative symmetry breaking in the IR. This phenomenon, and the multiplicative running of the operators that lies behind it, is akin...

  18. Novel four-point-probe design and nanorobotic dual endeffector strategy for electrical characterization of as-grown SWCNT bundles

    DEFF Research Database (Denmark)

    Eichhorn, V; Fatikow, S; Sardan Sukas, Özlem

    2010-01-01

    In this paper, a novel nanorobotic strategy for non-destructive and direct electrical characterization of as-grown bundles of single-walled carbon nanotubes (SWCNTs) is presented. For this purpose, test patterns of SWCNT bundles having different diameters are grown on a silicon substrate...... by chemical vapor deposition. A new design of microstructured four-point-probes is proposed and fabricated allowing for direct contacting of vertically aligned bundles of SWCNTs. A nanorobotic setup is upgraded into a dual endeffector system to achieve good electrical contact between four...

  19. A trust region interior point algorithm for optimal power flow problems

    Energy Technology Data Exchange (ETDEWEB)

    Wang Min [Hefei University of Technology (China). Dept. of Electrical Engineering and Automation; Liu Shengsong [Jiangsu Electric Power Dispatching and Telecommunication Company (China). Dept. of Automation

    2005-05-01

    This paper presents a new algorithm that uses the trust region interior point method to solve nonlinear optimal power flow (OPF) problems. The OPF problem is solved by a primal/dual interior point method with multiple centrality corrections as a sequence of linearized trust region sub-problems. It is the trust region that controls the linear step size and ensures the validity of the linear model. The convergence of the algorithm is improved through the modification of the trust region sub-problem. Numerical results of standard IEEE systems and two realistic networks ranging in size from 14 to 662 buses are presented. The computational results show that the proposed algorithm is very effective to optimal power flow applications, and favors the successive linear programming (SLP) method. Comparison with the predictor/corrector primal/dual interior point (PCPDIP) method is also made to demonstrate the superiority of the multiple centrality corrections technique. (author)

  20. Operating point considerations for the Reference Theta-Pinch Reactor (RTPR)

    International Nuclear Information System (INIS)

    Krakowski, R.A.; Miller, R.L.; Hagenson, R.L.

    1976-01-01

    Aspects of the continuing engineering design-point reassessment and optimization of the Reference Theta-Pinch Reactor (RTPR) are discussed. An updated interim design point which achieves a favorable energy balance and involves relaxed technological requirements, which nonetheless satisfy more rigorous physics and engineering constraints, is presented

  1. Designing for multiple global user populations: increasing resource allocation efficiency for greater sustainability.

    Science.gov (United States)

    Nadadur, G; Parkinson, M B

    2012-01-01

    This paper proposes a method to identify opportunities for increasing the efficiency of raw material allocation decisions for products that are simultaneously targeted at multiple user populations around the world. The values of 24 body measures at certain key percentiles were used to estimate the best-fitting anthropometric distributions for female and male adults in nine national populations, which were selected to represent the diverse target markets multinational companies must design for. These distributions were then used to synthesize body measure data for combined populations with a 1:1 female:male ratio. An anthropometric range metric (ARM) was proposed for assessing the variation of these body measures across the populations. At any percentile, ARM values were calculated as the percentage difference between the highest and lowest anthropometric values across the considered user populations. Based on their magnitudes, plots of ARM values computed between the 1st and 99 th percentiles for each body measure were grouped into low, medium, and high categories. This classification of body measures was proposed as a means of selecting the most suitable strategies for designing raw material-efficient products. The findings in this study and the contributions of subsequent work along these lines are expected to help achieve greater efficiencies in resource allocation in global product development.

  2. Critical Points of Contact

    DEFF Research Database (Denmark)

    Jensen, Ole B.; Wind, Simon; Lanng, Ditte Bendix

    2012-01-01

    In this brief article, we shall illustrate the application of the analytical and interventionist concept of ‘Critical Points of Contact’ (CPC) through a number of urban design studios. The notion of CPC has been developed over a span of the last three to four years and is reported in more detail...... elsewhere (Jensen & Morelli 2011). In this article, we will only discuss the conceptual and theoretical framing superficially, since our real interest is to show and discuss the concept's application value to spatial design in a number of urban design studios. The 'data' or the projects presented are seven...... in urban design at Aalborg University, where urban design consists of both an analytical and an interventionist field of operation. Furthermore, the content of the CPC concept links to research in mobilities, the network city, and urban design. These are among the core pillars of both the masters programme...

  3. Design Development of a Combined Deployment and Pointing System for the International Space Station Neutron Star Interior Composition Explorer Telescope

    Science.gov (United States)

    Budinoff, Jason; Gendreau, Keith; Arzoumanian, Zaven; Baker, Charles; Berning, Robert; Colangelo, TOdd; Holzinger, John; Lewis, Jesse; Liu, Alice; Mitchell, Alissa; hide

    2016-01-01

    This paper describes the design of a unique suite of mechanisms that make up the Deployment and Pointing System (DAPS) for the Neutron Star Interior Composition Explorer (NICER/SEXTANT) instrument, an X-Ray telescope, which will be mounted on the International Space Station (ISS). The DAPS system uses four stepper motor actuators to deploy the telescope box, latch it in the deployed position, and allow it to track sky targets. The DAPS gimbal architecture provides full-hemisphere coverage, and is fully re-stowable. The compact design of the mechanism allowed the majority of total instrument volume to be used for science. Override features allow DAPS to be stowed by ISS robotics.

  4. Growth Curve Analysis and Change-Points Detection in Extremes

    KAUST Repository

    Meng, Rui

    2016-05-15

    The thesis consists of two coherent projects. The first project presents the results of evaluating salinity tolerance in barley using growth curve analysis where different growth trajectories are observed within barley families. The study of salinity tolerance in plants is crucial to understanding plant growth and productivity. Because fully-automated smarthouses with conveyor systems allow non-destructive and high-throughput phenotyping of large number of plants, it is now possible to apply advanced statistical tools to analyze daily measurements and to study salinity tolerance. To compare different growth patterns of barley variates, we use functional data analysis techniques to analyze the daily projected shoot areas. In particular, we apply the curve registration method to align all the curves from the same barley family in order to summarize the family-wise features. We also illustrate how to use statistical modeling to account for spatial variation in microclimate in smarthouses and for temporal variation across runs, which is crucial for identifying traits of the barley variates. In our analysis, we show that the concentrations of sodium and potassium in leaves are negatively correlated, and their interactions are associated with the degree of salinity tolerance. The second project studies change-points detection methods in extremes when multiple time series data are available. Motived by the scientific question of whether the chances to experience extreme weather are different in different seasons of a year, we develop a change-points detection model to study changes in extremes or in the tail of a distribution. Most of existing models identify seasons from multiple yearly time series assuming a season or a change-point location remains exactly the same across years. In this work, we propose a random effect model that allows the change-point to vary from year to year, following a given distribution. Both parametric and nonparametric methods are developed

  5. Design and evaluation of pointing devices; Gestaltung und Evaluation von koordinatengebenden Interaktionsgeraeten

    Energy Technology Data Exchange (ETDEWEB)

    Krauss, L.; Zuehlke, D. [Kaiserslautern Univ. (Germany)

    2002-07-01

    Pointing devices e.g. the computer mouse are gaining considerable importance in modern human-machine-systems as a major part of the interaction interface between human beings and machines. During the dialogues with window-based operating systems the human being - the user - moves the cursor to a certain position on the screen by means of pointing devices. Microsoft products like WINDOWS have asserted themselves in the meantime in office applications and are currently conquering the market of industrial control systems as well. In office applications the mouse has become established as the most important pointing device for interaction. However, an 'office mouse' is not really suitable in a manufacturing environment. Only a few investigations exist evaluating alternatives to the mouse, which are suitable for industrial applications. At the Center of Human-Machine-Interaction (ZMMI) of the Institute of Production Automation (pak) at the University of Kaiserslautern a comparative investigation was carried out for alternative pointing devices like mouse, mousepad, mousebutton, mousestick, trackball, joystick, touchscreen, digitizing tablet and keyboard to determine their industrial suitability. This paper presents the methods of investigation and the most important results. The known Fitts' law model is mainly used in the field of HCl for office applications in order to evaluate interaction devices. This paper presents the new method DEVICE and is applied in the field of HMI for the evaluation of pointing devices. Tests with DEVICE and Fitts' method were conducted with machine operators under industrial environments to determine the suitability of thirty different pointing devices. The comparison between DEVICE and Fitts' law model shows that the results of certain partial tests correlate with each other. DEVICE can be used as substitute for Fitts' law model and offers additional parameters such as e.g. error rates and pointing deviation

  6. Statistical Power in Evaluations That Investigate Effects on Multiple Outcomes: A Guide for Researchers

    Science.gov (United States)

    Porter, Kristin E.

    2018-01-01

    Researchers are often interested in testing the effectiveness of an intervention on multiple outcomes, for multiple subgroups, at multiple points in time, or across multiple treatment groups. The resulting multiplicity of statistical hypothesis tests can lead to spurious findings of effects. Multiple testing procedures (MTPs) are statistical…

  7. Modeling a Single SEP Event from Multiple Vantage Points Using the iPATH Model

    Science.gov (United States)

    Hu, Junxiang; Li, Gang; Fu, Shuai; Zank, Gary; Ao, Xianzhi

    2018-02-01

    Using the recently extended 2D improved Particle Acceleration and Transport in the Heliosphere (iPATH) model, we model an example gradual solar energetic particle event as observed at multiple locations. Protons and ions that are energized via the diffusive shock acceleration mechanism are followed at a 2D coronal mass ejection-driven shock where the shock geometry varies across the shock front. The subsequent transport of energetic particles, including cross-field diffusion, is modeled by a Monte Carlo code that is based on a stochastic differential equation method. Time intensity profiles and particle spectra at multiple locations and different radial distances, separated in longitudes, are presented. The results shown here are relevant to the upcoming Parker Solar Probe mission.

  8. Learning Physics Teaching through Collaborative Design of Conceptual Multiple-Choice Questions

    Science.gov (United States)

    Milner-Bolotin, Marina

    2015-01-01

    Increasing student engagement through Electronic Response Systems (clickers) has been widely researched. Its success largely depends on the quality of multiple-choice questions used by instructors. This paper describes a pilot project that focused on the implementation of online collaborative multiple-choice question repository, PeerWise, in a…

  9. Some points of advanced alarm system design

    International Nuclear Information System (INIS)

    Hollo, E.

    1977-01-01

    A description of some of the more relevant questions relating to advanced alarm systems for nuclear power plant installations. The development of such alarm systems embodies three main tasks: development of formal alarm handling methods, design of alarm patterns, development of alarm analysis systems. The major aspects of these tests are dealt with and the close relation between the alarm analysis and the plant disturbance analysis procedure is emphasized. (author)

  10. Finding Non-Zero Stable Fixed Points of the Weighted Kuramoto model is NP-hard

    OpenAIRE

    Taylor, Richard

    2015-01-01

    The Kuramoto model when considered over the full space of phase angles [$0,2\\pi$) can have multiple stable fixed points which form basins of attraction in the solution space. In this paper we illustrate the fundamentally complex relationship between the network topology and the solution space by showing that determining the possibility of multiple stable fixed points from the network topology is NP-hard for the weighted Kuramoto Model. In the case of the unweighted model this problem is shown...

  11. Effect of incisor inclination changes on cephalometric points a and b

    International Nuclear Information System (INIS)

    Hassan, S.; Shaikh, A.; Fida, M.

    2015-01-01

    The position of cephalometric points A and B are liable to be affected by alveolar remodelling caused by orthodontic tooth movement during incisor retraction. This study was conducted to evaluate the change in positions of cephalometric points A and B in sagittal and vertical dimensions due to change in incisor inclinations. Methods: Total sample of 31 subjects were recruited into the study. The inclusion criteria were extraction of premolars in upper and lower arches, completion of growth and orthodontic treatment. The exclusion criteria were patients with craniofacial anomalies and history of orthodontic treatment. By superimposition of pre and post treatment tracings, various linear and angular parameters were measured. Various tests and multiple linear regression analysis were performed to determine changes in outcome variables. Statistically significant p-value was <0.05. Results:One-sample t-test showed that change in position of only point A was statistically significant which was 1.61mm (p<0.01) in sagittal direction and 1.49mm (p<0.01) in vertical direction. Multiple linear regression analysis showed that if we retrocline upper incisor by 100, the point A will move superiorly by 0.6mm. Conclusions: Total change in the position of point A is in a downward and forward direction. Total Change in upper incisors inclinations causes change in position of point A only in vertical direction. (author)

  12. Design Research on Mathematics Education: Investigating The Progress of Indonesian Fifth Grade Students’ Learning on Multiplication of Fractions With Natural Numbers

    Directory of Open Access Journals (Sweden)

    Nenden Octavarulia Shanty

    2011-07-01

    Full Text Available This study aimed at investigating the progress of students’ learning onmultiplication fractions with natural numbers through the five activitylevels based on Realistic Mathematics Education (RME approachproposed by Streefland. Design research was chosen to achieve thisresearch goal. In design research, the Hypothetical Learning Trajectory(HLT plays important role as a design and research instrument. ThisHLT tested to thirty-seven students of grade five primary school (i.e.SDN 179 Palembang.The result of the classroom practices showed that measurement (lengthactivity could stimulate students’ to produce fractions as the first levelin learning multiplication of fractions with natural numbers.Furthermore, strategies and tools used by the students in partitioninggradually be developed into a more formal mathematics in whichnumber line be used as the model of measuring situation and the modelfor more formal reasoning. The number line then could bring thestudents to the last activity level, namely on the way to rules formultiplying fractions with natural numbers. Based on this findings, it is suggested that Streefland’s five activity levels can be used as aguideline in learning multiplication of fractions with natural numbers in which the learning process become a more progressive learning.

  13. Clutter-free Visualization of Large Point Symbols at Multiple Scales by Offset Quadtrees

    Directory of Open Access Journals (Sweden)

    ZHANG Xiang

    2016-08-01

    Full Text Available To address the cartographic problems in map mash-up applications in the Web 2.0 context, this paper studies a clutter-free technique for visualizing large symbols on Web maps. Basically, a quadtree is used to select one symbol in each grid cell at each zoom level. To resolve the symbol overlaps between neighboring quad-grids, multiple offsets are applied to the quadtree and a voting strategy is used to compute the significant level of symbols for their selection at multiple scales. The method is able to resolve spatial conflicts without explicit conflict detection, thus enabling a highly efficient processing. Also the resulting map forms a visual hierarchy of semantic importance. We discuss issues such as the relative importance, symbol-to-grid size ratio, and effective offset schemes, and propose two extensions to make better use of the free space available on the map. Experiments were carried out to validate the technique,which demonstrates its robustness and efficiency (a non-optimal implementation leads to a sub-second processing for datasets of a 105 magnitude.

  14. NIM Realization of the Gallium Triple Point

    Science.gov (United States)

    Xiaoke, Yan; Ping, Qiu; Yuning, Duan; Yongmei, Qu

    2003-09-01

    In the last three years (1999 to 2001), the gallium triple-point cell has been successfully developed, and much corresponding research has been carried out at the National Institute of Metrology (NIM), Beijing, China. This paper presents the cell design, apparatus and procedure for realizing the gallium triple point, and presents studies on the different freezing methods. The reproducibility is 0.03 mK, and the expanded uncertainty of realization of the gallium triple point is evaluated to be 0.17 mK (p=0.99, k=2.9). Also, the reproducibility of the gallium triple point was compared with that of the triple point of water.

  15. Design and implementation of a contactless multiple hand feature acquisition system

    Science.gov (United States)

    Zhao, Qiushi; Bu, Wei; Wu, Xiangqian; Zhang, David

    2012-06-01

    In this work, an integrated contactless multiple hand feature acquisition system is designed. The system can capture palmprint, palm vein, and palm dorsal vein images simultaneously. Moreover, the images are captured in a contactless manner, that is, users need not to touch any part of the device when capturing. Palmprint is imaged under visible illumination while palm vein and palm dorsal vein are imaged under near infrared (NIR) illumination. The capturing is controlled by computer and the whole process is less than 1 second, which is sufficient for online biometric systems. Based on this device, this paper also implements a contactless hand-based multimodal biometric system. Palmprint, palm vein, palm dorsal vein, finger vein, and hand geometry features are extracted from the captured images. After similarity measure, the matching scores are fused using weighted sum fusion rule. Experimental results show that although the verification accuracy of each uni-modality is not as high as that of state-of-the-art, the fusion result is superior to most of the existing hand-based biometric systems. This result indicates that the proposed device is competent in the application of contactless multimodal hand-based biometrics.

  16. The current practice of using multiple representations in year 4 science classrooms

    Science.gov (United States)

    Chuenmanee, Chanoknat; Thathong, Kongsak

    2018-01-01

    Multiple representations have been widely used as a reasoning tool for understanding complex scientific concepts. Thus this study attempted to investigate the current practice of using multiple representations on Year 4 science classrooms in terms of modes and levels which appear in curriculum documents, teaching plans, tasks and assessments, teaching practices, and students' behaviors. Indeed, documentary analysis, classroom observation, and interview were used as the data collection methods. First of all, Year 4 science documents were analyzed. Then classroom observation was used as a collecting method to seek what actually happen in the classroom. Finally, in-depth interviews were used to gather more information and obtain meaningful data. The finding reveals that many modes of verbal, visual, and tactile representations within three levels of representations are posed in Year 4 documents. Moreover, according to classroom observations and interviews, there are three main points of applying multiple representations into classrooms. First of all, various modes of representations were used, however, a huge number of them did not come together with the levels. The levels of representations, secondly, macroscopic and cellular levels were introduced into all classrooms while symbolic level was provided only in some classrooms. Finally, the connection of modes and levels pointed out that modes of representations were used without the considerations on the levels of them. So, it seems to be that teaching practice did not meet the aims of curriculum. Therefore, these issues were being considered in order to organize and design the further science lessons.

  17. Mechanical design and optimal control of humanoid robot (TPinokio

    Directory of Open Access Journals (Sweden)

    Teck Chew Wee

    2014-04-01

    Full Text Available The mechanical structure and the control of the locomotion of bipedal humanoid is an important and challenging domain of research in bipedal robots. Accurate models of the kinematics and dynamics of the robot are essential to achieve bipedal locomotion. Toe-foot walking produces a more natural and faster walking speed and it is even possible to perform stretch knee walking. This study presents the mechanical design of a toe-feet bipedal, TPinokio and the implementation of some optimal walking gait generation methods. The optimality in the gait trajectory is achieved by applying augmented model predictive control method and the pole-zero cancellation method, taken into consideration of a trade-off between walking speed and stability. The mechanism of the TPinokio robot is designed in modular form, so that its kinematics can be modelled accurately into a multiple point-mass system, its dynamics is modelled using the single and double mass inverted pendulum model and zero-moment-point concept. The effectiveness of the design and control technique is validated by simulation testing with the robot walking on flat surface and climbing stairs.

  18. MOTION PLANNING OF MULTIPLE MOBILE ROBOTS COOPERATIVELY TRANSPORTING A COMMON OBJECT

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Many applications above the capability of a single robot need the cooperation of multiple mobile robots, but effective cooperation is hard to achieve. In this paper, a master-slave method is proposed to control the motions of multiple mobile robots that cooperatively transport a common object from a start point to a goal point. A noholonomic kinematic model to constrain the motions of multiple mobile robots is built in order to achieve cooperative motions of them, and a "Dynamic Coordinator" strategy is used to deal with the collision-avoidance of the master robot and slave robot individually. Simulation results show the robustness and effectiveness of the method.

  19. PointCom: semi-autonomous UGV control with intuitive interface

    Science.gov (United States)

    Rohde, Mitchell M.; Perlin, Victor E.; Iagnemma, Karl D.; Lupa, Robert M.; Rohde, Steven M.; Overholt, James; Fiorani, Graham

    2008-04-01

    Unmanned ground vehicles (UGVs) will play an important role in the nation's next-generation ground force. Advances in sensing, control, and computing have enabled a new generation of technologies that bridge the gap between manual UGV teleoperation and full autonomy. In this paper, we present current research on a unique command and control system for UGVs named PointCom (Point-and-Go Command). PointCom is a semi-autonomous command system for one or multiple UGVs. The system, when complete, will be easy to operate and will enable significant reduction in operator workload by utilizing an intuitive image-based control framework for UGV navigation and allowing a single operator to command multiple UGVs. The project leverages new image processing algorithms for monocular visual servoing and odometry to yield a unique, high-performance fused navigation system. Human Computer Interface (HCI) techniques from the entertainment software industry are being used to develop video-game style interfaces that require little training and build upon the navigation capabilities. By combining an advanced navigation system with an intuitive interface, a semi-autonomous control and navigation system is being created that is robust, user friendly, and less burdensome than many current generation systems. mand).

  20. Multiples least-squares reverse time migration

    KAUST Repository

    Zhang, Dongliang; Zhan, Ge; Dai, Wei; Schuster, Gerard T.

    2013-01-01

    To enhance the image quality, we propose multiples least-squares reverse time migration (MLSRTM) that transforms each hydrophone into a virtual point source with a time history equal to that of the recorded data. Since each recorded trace is treated

  1. Thermal-hydraulics design comparisons for the tandem mirror hybrid reactor blanket

    International Nuclear Information System (INIS)

    Wong, C.P.C.; Yang, Y.S.; Schultz, K.R.

    1980-09-01

    The Tandem Mirror Hybrid Reactor (TMHR) is a cylindrical reactor, and the fertile materials and tritium breeding fuel elements can be arranged with radial or axial orientation in the blanket module. Thermal-hydraulics performance comparisons were made between plate, axial rod and radial rod fuel geometrices. The three configurations result in different coolant/void fractions and different clad/structure fractions. The higher void fraction in the two rod designs means that these blankets will have to be thicker than the plate design blanket in order to achieve the same level of nuclear interactions. Their higher structural fractions will degrade the uranium breeding ratio and energy multiplication factor of the design. One difficulty in the thermal-hydraulics analysis of the plate design was caused by the varying energy multiplication of the blanket during the lifetime of the plate which forced the use of designs that operated in the transition flow regime at some point during life. To account for this, an approach was adopted from Gas Cooled Fast Reactor (GCFR) experience for the pressure drop calculation and the corresponding heat transfer coefficient that was used for the film drop thermal calculation. Because of the superior nuclear performance, the acceptable thermal-hydraulic characteristics and the mechanical design feasibility, the plate geometry concept was chosen for the reference gas-cooled TMHR blanket design

  2. Multiple Connections in RealXtend Architecture

    OpenAIRE

    Vatjus-Anttila, Jukka

    2012-01-01

    RealXtend is an open source virtual space platform implementing both client and server functionality. In the default implementation of realXtend, the client could only log in to one virtual space server at any given time. In this research an ability to make multiple simultaneous connections to virtual spaces was experimented. Focus of the research was on how to control multiple virtual spaces within the same client window from a technical point of view. This bachelor thesis presents metho...

  3. A versatile method for confirmatory evaluation of the effects of a covariate in multiple models

    DEFF Research Database (Denmark)

    Pipper, Christian Bressen; Ritz, Christian; Bisgaard, Hans

    2012-01-01

    to provide a fine-tuned control of the overall type I error in a wide range of epidemiological experiments where in reality no other useful alternative exists. The methodology proposed is applied to a multiple-end-point study of the effect of neonatal bacterial colonization on development of childhood asthma.......Modern epidemiology often requires testing of the effect of a covariate on multiple end points from the same study. However, popular state of the art methods for multiple testing require the tests to be evaluated within the framework of a single model unifying all end points. This severely limits...

  4. NorthPoint Courtesy Services Development and Design Summary

    Directory of Open Access Journals (Sweden)

    Daniel Cox

    2016-11-01

    Full Text Available As we address the topic of games on games, we turned our focus towards first-person shooters (FPS, one of the most popular genres of computer game at the moment. Contemporary FPS games populate the genre continuum from realistic (Rainbow Six Siege, ARMA, Insurgency to fantastic (Halo, Bioshock, Destiny. However, no matter the setting or context, a constant of the FPS genre is the horde of nameless non-player characters (NPCs that make up the waves of grunts and cannon fodder for the player character to enact their will against through the affordances provided by the designers. This melding of player will and designer limitations, in the vast majority of instances, results in NPCs being shot and killed with some form of weaponry, thus allowing the player to progress through the game.

  5. Electricity transmission pricing: Tracing based point-of-connection tariff

    International Nuclear Information System (INIS)

    Abhyankar, A.R.; Khaparde, S.A.

    2009-01-01

    Point-of-connection (POC) scheme of transmission pricing in decentralized markets charges the participants a single rate per MW depending on their point-of-connection. Use of grossly aggregated postage stamp rates as POC charges fails to provide appropriate price signals. The POC tariff based on distribution of network sunk costs by employing conventional tracing assures recovery of sunk costs based on extent of use of network by participants. However, the POC tariff by this method does not accommodate economically efficient price signals which correspond to marginal costs. On the other hand, the POC tariff, if made proportional to marginal costs alone, fails to account for sunk costs and extent of use of network. This paper overcomes these lacunae by combining the above stated desired objectives under the recently proposed optimal tracing framework. Since real power tracing problem is amenable to multiple solutions, it is formulated as linearly constrained optimization problem. By employing this methodology, consideration of extent of network use and sunk cost recovery are guaranteed, while objective function is designed such that the spatial pattern of price signals closely follows the pattern of scaled locational marginal prices. The methodology is tested on IEEE 30 bus system, wherein average power flow pattern is established by running various simulation states on congested and un-congested network conditions. (author)

  6. From Point Clouds to Definitions of Architectural Space

    DEFF Research Database (Denmark)

    Tamke, Martin; Blümel, Ina; Ochmann, Sebastian

    2014-01-01

    Regarding interior building topology as an important aspect in building design and management, several approaches to indoor point cloud structuring have been introduced recently. Apart from a high-level semantic segmentation of the formerly unstructured point clouds into stories and rooms...... possible applications of these approaches in architectural design and building management and comment on the possible benefits for the building profession. While contemporary practice of spatial arrangement is predominantly based on the manual iteration of spatial topologies, we show that the segmentation...

  7. Facilitating Multiple Intelligences Through Multimodal Learning Analytics

    Directory of Open Access Journals (Sweden)

    Ayesha PERVEEN

    2018-01-01

    Full Text Available This paper develops a theoretical framework for employing learning analytics in online education to trace multiple learning variations of online students by considering their potential of being multiple intelligences based on Howard Gardner’s 1983 theory of multiple intelligences. The study first emphasizes the need to facilitate students as multiple intelligences by online education systems and then suggests a framework of the advanced form of learning analytics i.e., multimodal learning analytics for tracing and facilitating multiple intelligences while they are engaged in online ubiquitous learning. As multimodal learning analytics is still an evolving area, it poses many challenges for technologists, educationists as well as organizational managers. Learning analytics make machines meet humans, therefore, the educationists with an expertise in learning theories can help technologists devise latest technological methods for multimodal learning analytics and organizational managers can implement them for the improvement of online education. Therefore, a careful instructional design based on a deep understanding of students’ learning abilities, is required to develop teaching plans and technological possibilities for monitoring students’ learning paths. This is how learning analytics can help design an adaptive instructional design based on a quick analysis of the data gathered. Based on that analysis, the academicians can critically reflect upon the quick or delayed implementation of the existing instructional design based on students’ cognitive abilities or even about the single or double loop learning design. The researcher concludes that the online education is multimodal in nature, has the capacity to endorse multiliteracies and, therefore, multiple intelligences can be tracked and facilitated through multimodal learning analytics in an online mode. However, online teachers’ training both in technological implementations and

  8. Multiple Information Fusion Face Recognition Using Key Feature Points

    Directory of Open Access Journals (Sweden)

    LIN Kezheng

    2017-06-01

    Full Text Available After years of face recognition research,due to the effect of illumination,noise and other conditions have led to the recognition rate is relatively low,2 d face recognition technology has couldn’t keep up with the pace of The Times the forefront,Although 3 d face recognition technology is developing step by step,but it has a higher complexity. In order to solve this problem,based on the traditional depth information positioning method and local characteristic analysis methods LFA,puts forward an improved 3 d face key feature points localization algorithm, and on the basis of the trained sample which obtained by complete cluster,further put forward the global and local feature extraction algorithm of weighted fusion. Through FRGC and BU-3DFE experiment data comparison and analysis of the two face library,the method in terms of 3 d face recognition effect has a higher robustness.

  9. Optimal design of structures with multiple design variables per group and multiple loading conditions on the personal computer

    Science.gov (United States)

    Nguyen, D. T.; Rogers, J. L., Jr.

    1986-01-01

    A finite element based programming system for minimum weight design of a truss-type structure subjected to displacement, stress, and lower and upper bounds on design variables is presented. The programming system consists of a number of independent processors, each performing a specific task. These processors, however, are interfaced through a well-organized data base, thus making the tasks of modifying, updating, or expanding the programming system much easier in a friendly environment provided by many inexpensive personal computers. The proposed software can be viewed as an important step in achieving a 'dummy' finite element for optimization. The programming system has been implemented on both large and small computers (such as VAX, CYBER, IBM-PC, and APPLE) although the focus is on the latter. Examples are presented to demonstrate the capabilities of the code. The present programming system can be used stand-alone or as part of the multilevel decomposition procedure to obtain optimum design for very large scale structural systems. Furthermore, other related research areas such as developing optimization algorithms (or in the larger level: a structural synthesis program) for future trends in using parallel computers may also benefit from this study.

  10. Design Methodology for Multiple Microcomputer Architectures.

    Science.gov (United States)

    1982-07-01

    multimicro design knowledge is true both in industry and in university environments. In the industrial environment, it reduces productivity and increases...Real-Time Processor Problems," Proc. of ELECTRO-81 Tercer Seminario de Ingenieria Electronica, Nov. 9-13, 1981. 14 1981 "D Flip/Flop Substracts

  11. EURAMET.T-K7 Key Comparison of Water Triple-Point Cells

    Science.gov (United States)

    Peruzzi, A.; Bosma, R.; Kerkhof, O.; Rosenkranz, P.; Del Campo Maldonado, M. D.; Strnad, R.; Nielsen, J.; Anagnostou, M.; Veliki, T.; Zvizdic, D.; Grudnewicz, E.; Nedea, M.; Neagu, D. M.; Steur, P.; Filipe, E.; Lobo, I.; Antonsen, I.; Renaot, E.; Heinonen, M.; Weckstrom, T.; Bojkovski, J.; Turzo-Andras, E.; Nemeth, S.; White, M.; Tegeler, E.; Dobre, M.; Duris, S.; Kartal Dogan, A.; Uytun, A.; Augevicius, V.; Pauzha, A.; Pokhodun, A.; Simic, S.

    2011-12-01

    The results of a EURAMET key comparison of water triple-point cells (EURAMET.T-K7) are reported. The equipment used, the measuring conditions applied, and the procedures adopted for the water triple-point measurement at the participating laboratories are synthetically presented. The definitions of the national reference for the water triple-point temperature adopted by each laboratory are disclosed. The multiplicity of degrees of equivalence arising for the linking laboratories with respect to the "mother" comparison CCT-K7 is discussed in detail.

  12. Optimal Design of Multitype Groundwater Monitoring Networks Using Easily Accessible Tools.

    Science.gov (United States)

    Wöhling, Thomas; Geiges, Andreas; Nowak, Wolfgang

    2016-11-01

    Monitoring networks are expensive to establish and to maintain. In this paper, we extend an existing data-worth estimation method from the suite of PEST utilities with a global optimization method for optimal sensor placement (called optimal design) in groundwater monitoring networks. Design optimization can include multiple simultaneous sensor locations and multiple sensor types. Both location and sensor type are treated simultaneously as decision variables. Our method combines linear uncertainty quantification and a modified genetic algorithm for discrete multilocation, multitype search. The efficiency of the global optimization is enhanced by an archive of past samples and parallel computing. We demonstrate our methodology for a groundwater monitoring network at the Steinlach experimental site, south-western Germany, which has been established to monitor river-groundwater exchange processes. The target of optimization is the best possible exploration for minimum variance in predicting the mean travel time of the hyporheic exchange. Our results demonstrate that the information gain of monitoring network designs can be explored efficiently and with easily accessible tools prior to taking new field measurements or installing additional measurement points. The proposed methods proved to be efficient and can be applied for model-based optimal design of any type of monitoring network in approximately linear systems. Our key contributions are (1) the use of easy-to-implement tools for an otherwise complex task and (2) yet to consider data-worth interdependencies in simultaneous optimization of multiple sensor locations and sensor types. © 2016, National Ground Water Association.

  13. Pointo - a Low Cost Solution to Point Cloud Processing

    Science.gov (United States)

    Houshiar, H.; Winkler, S.

    2017-11-01

    With advance in technology access to data especially 3D point cloud data becomes more and more an everyday task. 3D point clouds are usually captured with very expensive tools such as 3D laser scanners or very time consuming methods such as photogrammetry. Most of the available softwares for 3D point cloud processing are designed for experts and specialists in this field and are usually very large software packages containing variety of methods and tools. This results in softwares that are usually very expensive to acquire and also very difficult to use. Difficulty of use is caused by complicated user interfaces that is required to accommodate a large list of features. The aim of these complex softwares is to provide a powerful tool for a specific group of specialist. However they are not necessary required by the majority of the up coming average users of point clouds. In addition to complexity and high costs of these softwares they generally rely on expensive and modern hardware and only compatible with one specific operating system. Many point cloud customers are not point cloud processing experts or willing to spend the high acquisition costs of these expensive softwares and hardwares. In this paper we introduce a solution for low cost point cloud processing. Our approach is designed to accommodate the needs of the average point cloud user. To reduce the cost and complexity of software our approach focuses on one functionality at a time in contrast with most available softwares and tools that aim to solve as many problems as possible at the same time. Our simple and user oriented design improve the user experience and empower us to optimize our methods for creation of an efficient software. In this paper we introduce Pointo family as a series of connected softwares to provide easy to use tools with simple design for different point cloud processing requirements. PointoVIEWER and PointoCAD are introduced as the first components of the Pointo family to provide a

  14. Generalized internal multiple imaging

    KAUST Repository

    Zuberi, M. A. H.

    2014-08-05

    Internal multiples deteriorate the image when the imaging procedure assumes only single scattering, especially if the velocity model does not have sharp contrasts to reproduce such scattering in the Green’s function through forward modeling. If properly imaged, internal multiples (internally scattered energy) can enhance the seismic image. Conventionally, to image internal multiples, accurate, sharp contrasts in the velocity model are required to construct a Green’s function with all the scattered energy. As an alternative, we have developed a generalized internal multiple imaging procedure that images any order internal scattering using the background Green’s function (from the surface to each image point), constructed from a smooth velocity model, usually used for conventional imaging. For the first-order internal multiples, the approach consisted of three steps, in which we first back propagated the recorded surface seismic data using the background Green’s function, then crosscorrelated the back-propagated data with the recorded data, and finally crosscorrelated the result with the original background Green’s function. This procedure images the contribution of the recorded first-order internal multiples, and it is almost free of the single-scattering recorded energy. The cost includes one additional crosscorrelation over the conventional single-scattering imaging application. We generalized this method to image internal multiples of any order separately. The resulting images can be added to the conventional single-scattering image, obtained, e.g., from Kirchhoff or reverse-time migration, to enhance the image. Application to synthetic data with reflectors illuminated by multiple scattering (double scattering) demonstrated the effectiveness of the approach.

  15. NRC Information No. 88-86: Operating with multiple grounds in direct current distribution systems

    International Nuclear Information System (INIS)

    Rossi, C.E.

    1992-01-01

    During recent NRC maintenance inspections at Quad Cities, Oconee, and D.C. Cook power reactor facilities, it was found that plants had been operating with multiple grounds in the dc distribution systems for extended periods. Specific examples are described. Most nuclear power plant dc systems are two-wire ungrounded, combination battery/charger systems equipped with ground detection. Typical ground detection system features include a remote annunciator and a local indicator and/or recorder. Ground detectors are incorporated in the dc system so that if a single ground point does occur, immediate steps can be taken to clear the ground fault from the system. Failure to respond to a single ground will mask subsequent grounds. Multiple grounds can cause the indiscriminate operation of equipment, which may have safety consequences. Grounds can cause control circuit fuses to fail and can render important safety equipment inoperable as previously described. Furthermore, batteries have a designed capacity to supply power during a station blackout condition, and this capacity can be affected by the presence of unanalyzed loads in the form of multiple grounds. It is recognized that troubleshooting and finding grounds on a dc system are difficult tasks that may affect plant operation. The licensees previously mentioned have reviewed their designs and conditions for potential impact on safety system operability and have taken corrective actions to minimize the effect of grounds

  16. RNAblueprint: flexible multiple target nucleic acid sequence design.

    Science.gov (United States)

    Hammer, Stefan; Tschiatschek, Birgit; Flamm, Christoph; Hofacker, Ivo L; Findeiß, Sven

    2017-09-15

    Realizing the value of synthetic biology in biotechnology and medicine requires the design of molecules with specialized functions. Due to its close structure to function relationship, and the availability of good structure prediction methods and energy models, RNA is perfectly suited to be synthetically engineered with predefined properties. However, currently available RNA design tools cannot be easily adapted to accommodate new design specifications. Furthermore, complicated sampling and optimization methods are often developed to suit a specific RNA design goal, adding to their inflexibility. We developed a C ++  library implementing a graph coloring approach to stochastically sample sequences compatible with structural and sequence constraints from the typically very large solution space. The approach allows to specify and explore the solution space in a well defined way. Our library also guarantees uniform sampling, which makes optimization runs performant by not only avoiding re-evaluation of already found solutions, but also by raising the probability of finding better solutions for long optimization runs. We show that our software can be combined with any other software package to allow diverse RNA design applications. Scripting interfaces allow the easy adaption of existing code to accommodate new scenarios, making the whole design process very flexible. We implemented example design approaches written in Python to demonstrate these advantages. RNAblueprint , Python implementations and benchmark datasets are available at github: https://github.com/ViennaRNA . s.hammer@univie.ac.at, ivo@tbi.univie.ac.at or sven@tbi.univie.ac.at. Supplementary data are available at Bioinformatics online. © The Author(s) 2017. Published by Oxford University Press.

  17. Modern drug design: the implication of using artificial neuronal networks and multiple molecular dynamic simulations

    Science.gov (United States)

    Yakovenko, Oleksandr; Jones, Steven J. M.

    2018-01-01

    We report the implementation of molecular modeling approaches developed as a part of the 2016 Grand Challenge 2, the blinded competition of computer aided drug design technologies held by the D3R Drug Design Data Resource (https://drugdesigndata.org/). The challenge was focused on the ligands of the farnesoid X receptor (FXR), a highly flexible nuclear receptor of the cholesterol derivative chenodeoxycholic acid. FXR is considered an important therapeutic target for metabolic, inflammatory, bowel and obesity related diseases (Expert Opin Drug Metab Toxicol 4:523-532, 2015), but in the context of this competition it is also interesting due to the significant ligand-induced conformational changes displayed by the protein. To deal with these conformational changes we employed multiple simulations of molecular dynamics (MD). Our MD-based protocols were top-ranked in estimating the free energy of binding of the ligands and FXR protein. Our approach was ranked second in the prediction of the binding poses where we also combined MD with molecular docking and artificial neural networks. Our approach showed mediocre results for high-throughput scoring of interactions.

  18. Design of all-optical high-order temporal integrators based on multiple-phase-shifted Bragg gratings.

    Science.gov (United States)

    Asghari, Mohammad H; Azaña, José

    2008-07-21

    In exact analogy with their electronic counterparts, photonic temporal integrators are fundamental building blocks for constructing all-optical circuits for ultrafast information processing and computing. In this work, we introduce a simple and general approach for realizing all-optical arbitrary-order temporal integrators. We demonstrate that the N(th) cumulative time integral of the complex field envelope of an input optical waveform can be obtained by simply propagating this waveform through a single uniform fiber/waveguide Bragg grating (BG) incorporating N pi-phase shifts along its axial profile. We derive here the design specifications of photonic integrators based on multiple-phase-shifted BGs. We show that the phase shifts in the BG structure can be arbitrarily located along the grating length provided that each uniform grating section (sections separated by the phase shifts) is sufficiently long so that its associated peak reflectivity reaches nearly 100%. The resulting designs are demonstrated by numerical simulations assuming all-fiber implementations. Our simulations show that the proposed approach can provide optical operation bandwidths in the tens-of-GHz regime using readily feasible photo-induced fiber BG structures.

  19. Finding a single point of truth

    Energy Technology Data Exchange (ETDEWEB)

    Sokolov, S.; Thijssen, H. [Autodesk Inc, Toronto, ON (Canada); Laslo, D.; Martin, J. [Autodesk Inc., San Rafael, CA (United States)

    2010-07-01

    Electric utilities collect large volumes of data at every level of their business, including SCADA, Smart Metering and Smart Grid initiatives, LIDAR and other 3D imagery surveys. Different types of database systems are used to store the information, rendering data flow within the utility business process extremely complicated. The industry trend has been to endure redundancy of data input and maintenance of multiple copies of the same data across different solution data sets. Efforts have been made to improve the situation with point to point interfaces, but with the tools and solutions available today, a single point of truth can be achieved. Consolidated and validated data can be published into a data warehouse at the right point in the process, making the information available to all other enterprise systems and solutions. This paper explained how the single point of truth spatial data warehouse and process automation services can be configured to streamline the flow of data within the utility business process using the initiate-plan-execute-close (IPEC) utility workflow model. The paper first discussed geospatial challenges faced by utilities and then presented the approach and technology aspects. It was concluded that adoption of systems and solutions that can function with and be controlled by the IPEC workflow can provide significant improvement for utility operations, particularly if those systems are coupled with the spatial data warehouse that reflects a single point of truth. 6 refs., 3 figs.

  20. Point-of-Purchase Advertising. Learning Activity.

    Science.gov (United States)

    Shackelford, Ray

    1998-01-01

    In this technology education activity, students learn the importance of advertising, conduct a day-long survey of advertising strategies, and design and produce a tabletop point-of-purchase advertisement. (JOW)

  1. Design and protocol of a randomized multiple behavior change trial: Make Better Choices 2 (MBC2).

    Science.gov (United States)

    Pellegrini, Christine A; Steglitz, Jeremy; Johnston, Winter; Warnick, Jennifer; Adams, Tiara; McFadden, H G; Siddique, Juned; Hedeker, Donald; Spring, Bonnie

    2015-03-01

    Suboptimal diet and inactive lifestyle are among the most prevalent preventable causes of premature death. Interventions that target multiple behaviors are potentially efficient; however the optimal way to initiate and maintain multiple health behavior changes is unknown. The Make Better Choices 2 (MBC2) trial aims to examine whether sustained healthful diet and activity change are best achieved by targeting diet and activity behaviors simultaneously or sequentially. Study design approximately 250 inactive adults with poor quality diet will be randomized to 3 conditions examining the best way to prescribe healthy diet and activity change. The 3 intervention conditions prescribe: 1) an increase in fruit and vegetable consumption (F/V+), decrease in sedentary leisure screen time (Sed-), and increase in physical activity (PA+) simultaneously (Simultaneous); 2) F/V+ and Sed- first, and then sequentially add PA+ (Sequential); or 3) Stress Management Control that addresses stress, relaxation, and sleep. All participants will receive a smartphone application to self-monitor behaviors and regular coaching calls to help facilitate behavior change during the 9 month intervention. Healthy lifestyle change in fruit/vegetable and saturated fat intakes, sedentary leisure screen time, and physical activity will be assessed at 3, 6, and 9 months. MBC2 is a randomized m-Health intervention examining methods to maximize initiation and maintenance of multiple healthful behavior changes. Results from this trial will provide insight about an optimal technology supported approach to promote improvement in diet and physical activity. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. Adaptive Control Design for Autonomous Operation of Multiple Energy Storage Systems in Power Smoothing Applications

    DEFF Research Database (Denmark)

    Meng, Lexuan; Dragicevic, Tomislav; Guerrero, Josep M.

    2018-01-01

    -pass-filter (HPF) structure. It generates the power reference according to the fluctuating power and provides a stabilization effect. The power and energy supplied by ESS are majorly configured by the cut-off frequency and gain of the HPF. Considering the operational limits on ESS state-of-charge (SoC), this paper...... proposes an adaptive cut-off frequency design method to realize communication-less and autonomous operation of a system with multiple distributed ESS. The experimental results demonstrate that the SoCs of all ESS units are kept within safe margins, while the SoC level and power of the paralleled units...... converge to the final state, providing a natural plug-and-play function....

  3. TMACS I/O termination point listing. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Scaief, C.C. III

    1994-09-13

    This document provides a listing of all analog and discrete input/output (I/O) points connected to the Tank Monitor and Control System (TMACS). The list also provides other information such as the point tag name, termination location, description, drawing references and other parameters. The purpose is to define each point`s unique tag name and to cross reference the point with other associated information that may be necessary for activities such as maintenance, calibration, diagnostics, or design changes. It provides a list in one document of all I/O points that would otherwise only be available by referring to all I/O termination drawings.

  4. Can Free-Response Questions Be Approximated by Multiple-Choice Equivalents?

    OpenAIRE

    Lin, Shih-Yin; Singh, Chandralekha

    2016-01-01

    We discuss a study to evaluate the extent to which free-response questions can be approximated by multiple-choice equivalents. Two carefully designed research-based multiple-choice questions were transformed into a free-response format and administered on the final exam in a calculus-based introductory physics course. The original multiple-choice questions were administered in another, similar introductory physics course on the final exam. Our findings suggest that carefully designed multiple...

  5. Realtime control of multiple-focus phased array heating patterns based on noninvasive ultrasound thermography.

    Science.gov (United States)

    Casper, Andrew; Liu, Dalong; Ebbini, Emad S

    2012-01-01

    A system for the realtime generation and control of multiple-focus ultrasound phased-array heating patterns is presented. The system employs a 1-MHz, 64-element array and driving electronics capable of fine spatial and temporal control of the heating pattern. The driver is integrated with a realtime 2-D temperature imaging system implemented on a commercial scanner. The coordinates of the temperature control points are defined on B-mode guidance images from the scanner, together with the temperature set points and controller parameters. The temperature at each point is controlled by an independent proportional, integral, and derivative controller that determines the focal intensity at that point. Optimal multiple-focus synthesis is applied to generate the desired heating pattern at the control points. The controller dynamically reallocates the power available among the foci from the shared power supply upon reaching the desired temperature at each control point. Furthermore, anti-windup compensation is implemented at each control point to improve the system dynamics. In vitro experiments in tissue-mimicking phantom demonstrate the robustness of the controllers for short (2-5 s) and longer multiple-focus high-intensity focused ultrasound exposures. Thermocouple measurements in the vicinity of the control points confirm the dynamics of the temperature variations obtained through noninvasive feedback. © 2011 IEEE

  6. Statistical Power in Evaluations That Investigate Effects on Multiple Outcomes: A Guide for Researchers

    Science.gov (United States)

    Porter, Kristin E.

    2016-01-01

    In education research and in many other fields, researchers are often interested in testing the effectiveness of an intervention on multiple outcomes, for multiple subgroups, at multiple points in time, or across multiple treatment groups. The resulting multiplicity of statistical hypothesis tests can lead to spurious findings of effects. Multiple…

  7. Power Trip Set-points of Reactor Protection System for New Research Reactor

    International Nuclear Information System (INIS)

    Lee, Byeonghee; Yang, Soohyung

    2013-01-01

    This paper deals with the trip set-point related to the reactor power considering the reactivity induced accident (RIA) of new research reactor. The possible scenarios of reactivity induced accidents were simulated and the effects of trip set-point on the critical heat flux ratio (CHFR) were calculated. The proper trip set-points which meet the acceptance criterion and guarantee sufficient margins from normal operation were then determined. The three different trip set-points related to the reactor power are determined based on the RIA of new research reactor during FP condition, over 0.1%FP and under 0.1%FP. Under various reactivity insertion rates, the CHFR are calculated and checked whether they meet the acceptance criterion. For RIA at FP condition, the acceptance criterion can be satisfied even if high power set-point is only used for reactor trip. Since the design of the reactor is still progressing and need a safety margin for possible design changes, 18 MW is recommended as a high power set-point. For RIA at 0.1%FP, high power setpoint of 18 MW and high log rate of 10%pp/s works well and acceptance criterion is satisfied. For under 0.1% FP operations, the application of high log rate is necessary for satisfying the acceptance criterion. Considering possible decrease of CHFR margin due to design changes, the high log rate is suggested to be 8%pp/s. Suggested trip set-points have been identified based on preliminary design data for new research reactor; therefore, these trip set-points will be re-established by considering design progress of the reactor. The reactor protection system (RPS) of new research reactor is designed for safe shutdown of the reactor and preventing the release of radioactive material to environment. The trip set point of RPS is essential for reactor safety, therefore should be determined to mitigate the consequences from accidents. At the same time, the trip set-point should secure margins from normal operational condition to avoid

  8. More Stamina, a Gamified mHealth Solution for Persons with Multiple Sclerosis: Research Through Design

    Science.gov (United States)

    Mylonopoulou, Vasiliki; Rivera Romero, Octavio

    2018-01-01

    Background Multiple sclerosis (MS) is one of the world’s most common neurologic disorders. Fatigue is one of most common symptoms that persons with MS experience, having significant impact on their quality of life and limiting their activity levels. Self-management strategies are used to support them in the care of their health. Mobile health (mHealth) solutions are a way to offer persons with chronic conditions tools to successfully manage their symptoms and problems. Gamification is a current trend among mHealth apps used to create engaging user experiences and is suggested to be effective for behavioral change. To be effective, mHealth solutions need to be designed to specifically meet the intended audience needs. User-centered design (UCD) is a design philosophy that proposes placing end users’ needs and characteristics in the center of design and development, involving users early in the different phases of the software life cycle. There is a current gap in mHealth apps for persons with MS, which presents an interesting area to explore. Objective The purpose of this study was to describe the design and evaluation process of a gamified mHealth solution for behavioral change in persons with MS using UCD. Methods Building on previous work of our team where we identified needs, barriers, and facilitators for mHealth apps for persons with MS, we followed UCD to design and evaluate a mobile app prototype aimed to help persons with MS self-manage their fatigue. Design decisions were evidence-driven and guided by behavioral change models (BCM). Usability was assessed through inspection methods using Nielsen’s heuristic evaluation. Results The mHealth solution More Stamina was designed. It is a task organization tool designed to help persons with MS manage their energy to minimize the impact of fatigue in their day-to-day life. The tool acts as a to-do list where users can input tasks in a simple manner and assign Stamina Credits, a representation of perceived

  9. A framework for multiple kernel support vector regression and its applications to siRNA efficacy prediction.

    Science.gov (United States)

    Qiu, Shibin; Lane, Terran

    2009-01-01

    The cell defense mechanism of RNA interference has applications in gene function analysis and promising potentials in human disease therapy. To effectively silence a target gene, it is desirable to select appropriate initiator siRNA molecules having satisfactory silencing capabilities. Computational prediction for silencing efficacy of siRNAs can assist this screening process before using them in biological experiments. String kernel functions, which operate directly on the string objects representing siRNAs and target mRNAs, have been applied to support vector regression for the prediction and improved accuracy over numerical kernels in multidimensional vector spaces constructed from descriptors of siRNA design rules. To fully utilize information provided by string and numerical data, we propose to unify the two in a kernel feature space by devising a multiple kernel regression framework where a linear combination of the kernels is used. We formulate the multiple kernel learning into a quadratically constrained quadratic programming (QCQP) problem, which although yields global optimal solution, is computationally demanding and requires a commercial solver package. We further propose three heuristics based on the principle of kernel-target alignment and predictive accuracy. Empirical results demonstrate that multiple kernel regression can improve accuracy, decrease model complexity by reducing the number of support vectors, and speed up computational performance dramatically. In addition, multiple kernel regression evaluates the importance of constituent kernels, which for the siRNA efficacy prediction problem, compares the relative significance of the design rules. Finally, we give insights into the multiple kernel regression mechanism and point out possible extensions.

  10. Focusing: coming to the point in metamaterials

    Science.gov (United States)

    Guenneau, S.; Diatta, A.; McPhedran, R. C.

    2010-04-01

    This paper reviews some properties of lenses in curved and folded optical spaces. The point of the paper is to show some limitations of geometrical optics in the analysis of subwavelength focusing. We first provide a comprehensive derivation for the equation of geodesics in curved optical spaces, which is a tool of choice to design metamaterials in transformation optics. We then analyse the resolution of the image of a line source radiating in the Maxwell fisheye and the Veselago-Pendry slab lens. The former optical medium is deduced from the stereographic projection of a virtual sphere and displays a heterogeneous refractive index n(r) which is proportional to the inverse of 1 + r 2. The latter is described by a homogeneous, but negative, refractive index. It has been suggested that the fisheye makes a perfect lens without negative refraction [Leonhardt, Philbin arxiv:0805.4778v2]. However, we point out that the definition of super-resolution in such a heterogeneous medium should be computed with respect to the wavelength in a homogenised medium, and it is perhaps more adequate to talk about a conjugate image rather than a perfect image (the former does not necessarily contain the evanescent components of the source). We numerically find that both the Maxwell fisheye and a thick silver slab lens lead to a resolution close to λ/3 in transverse magnetic polarisation (electric field pointing orthogonal to the plane). We note a shift of the image plane in the latter lens. We also observe that two sources lead to multiple secondary images in the former lens, as confirmed from light rays travelling along geodesics of the virtual sphere. We further observe resolutions ranging from λ/2 to nearly λ/4 for magnetic dipoles of varying orientations of dipole moments within the fisheye in transverse electric polarisation (magnetic field pointing orthogonal to the plane). Finally, we analyse the Eaton lens for which the source and its image are either located within a unit

  11. Plutonium hydrolysis and the double double-point

    International Nuclear Information System (INIS)

    Silver, G.L.

    2011-01-01

    There is uncertainty about the numerical value of the first hydrolysis constant of the tetravalent plutonium ion. A new method for discriminating between the claims is illustrated. It suggests the traditional estimates of that constant are closer to its true value than a singular result based on a few solvent-extraction experiments. A previously unnoticed multiple point in aqueous Pu chemistry is illustrated. (author)

  12. Structure of the magnetopause current layer at the subsolar point

    International Nuclear Information System (INIS)

    Okuda, H.

    1991-12-01

    A one-dimensional electromagnetic particle simulation model developed for the magnetopause current layer between the shocked solar wind and the dipole magnetic field at the subsolar point has been extended to include the interplanetary magnetic field (IMF) in the solar wind. Interaction of the solar wind with the vacuum dipole field as well as the dipole field filled with a low density magnetospheric plasma are studied. It is found that the width and the structure of the magnetopause current layer differ markedly depending on the direction of the IMF. When the IMF is pointing southward, the current layer between the solar wind and the dipole field is narrow and the magnetic field has a single ramp structure caused by the reflection of the solar wind at that point. The current layer becomes several times wider and the magnetic field developes a multiple ramp structure when the IMF is northward. This broadening of the current layer is caused by the multiple reflection of the solar wind by the magnetic field. For the northward IMF, the magnetic field does not change its sign across the current layer so that the E x B drift of the solar wind electrons remains the same direction while for the southward IMF, it reverses the sign. This results in a single reflection of the solar wind for the southward IMF and multiple reflections for the northward IMF. When a low density mangetospheric plasma is present in the dipole magnetic field, a small fraction of the solar wind ions are found to penetrate into the dipole magnetic field beyond the reflection point of the solar wind electrons. The width of the ion current layer is of the order of the solar wind ion gyroradius, however, the current associated with the ions remains much smaller than the electron current so long as the density of the magnetospheric plasma is much smaller than the density of the solar wind. Comparisons of our simulation results with the magnetopause crossing near the subsolar point are provided

  13. Design, simulation and fabrication of a novel contact-enhanced MEMS inertial switch with a movable contact point

    International Nuclear Information System (INIS)

    Cai Haogang; Ding Guifu; Yang Zhuoqing; Su Zhijuan; Zhou Jiansheng; Wang Hong

    2008-01-01

    A novel inertial switch based on a micro-electro-mechanical system (MEMS) was designed, which consists of three main parts: a proof mass as the movable electrode, a cross beam as the stationary electrode and a movable contact point to prolong the contact time. A MATLAB/Simulink model, which had been verified by comparison with ANSYS transient simulation, was built to simulate the dynamic response, based on which the contact-enhancing mechanism was confirmed and the dependence of threshold acceleration on the proof mass thickness was studied. The simulated dynamic responses under various accelerations exhibit satisfactory device behaviors: the switch-on time is prolonged under transient acceleration; the switch-on state is more continuous than the conventional design under long lasting acceleration. The inertial micro-switch was fabricated by multilayer electroplating technology and then tested by a drop hammer experiment. The test results indicate that the contact effect was improved significantly and a steady switch-on time of over 50 µs was observed under half-sine wave acceleration with 1 ms duration, in agreement with the dynamic simulation

  14. Distributed Fusion Estimation for Multisensor Multirate Systems with Stochastic Observation Multiplicative Noises

    Directory of Open Access Journals (Sweden)

    Peng Fangfang

    2014-01-01

    Full Text Available This paper studies the fusion estimation problem of a class of multisensor multirate systems with observation multiplicative noises. The dynamic system is sampled uniformly. Sampling period of each sensor is uniform and the integer multiple of the state update period. Moreover, different sensors have the different sampling rates and observations of sensors are subject to the stochastic uncertainties of multiplicative noises. At first, local filters at the observation sampling points are obtained based on the observations of each sensor. Further, local estimators at the state update points are obtained by predictions of local filters at the observation sampling points. They have the reduced computational cost and a good real-time property. Then, the cross-covariance matrices between any two local estimators are derived at the state update points. At last, using the matrix weighted optimal fusion estimation algorithm in the linear minimum variance sense, the distributed optimal fusion estimator is obtained based on the local estimators and the cross-covariance matrices. An example shows the effectiveness of the proposed algorithms.

  15. Design of multi-function sensor detection system in coal mine based on ARM

    Science.gov (United States)

    Ge, Yan-Xiang; Zhang, Quan-Zhu; Deng, Yong-Hong

    2017-06-01

    The traditional coal mine sensor in the specific measurement points, the number and type of channel will be greater than or less than the number of monitoring points, resulting in a waste of resources or cannot meet the application requirements, in order to enable the sensor to adapt to the needs of different occasions and reduce the cost, a kind of multi-functional intelligent sensor multiple sensors and ARM11 the S3C6410 processor is used to design and realize the dust, gas, temperature and humidity sensor functions together, and has storage, display, voice, pictures, data query, alarm and other new functions.

  16. Testing of the BipiColombo Antenna Pointing Mechanism

    Science.gov (United States)

    Campo, Pablo; Barrio, Aingeru; Martin, Fernando

    2015-09-01

    BepiColombo is an ESA mission to Mercury, its planetary orbiter (MPO) has two antenna pointing mechanism, High gain antenna (HGA) pointing mechanism steers and points a large reflector which is integrated at system level by TAS-I Rome. Medium gain antenna (MGA) APM points a 1.5 m boom with a horn antenna. Both radiating elements are exposed to sun fluxes as high as 10 solar constants without protections.A previous paper [1] described the design and development process to solve the challenges of performing in harsh environment.. Current paper is focused on the testing process of the qualification units. Testing performance of antenna pointing mechanism in its specific environmental conditions has required special set-up and techniques. The process has provided valuable feedback on the design and the testing methods which have been included in the PFM design and tests.Some of the technologies and components were developed on dedicated items priort to EQM, but once integrated, test behaviour had relevant differences.Some of the major concerns for the APM testing are:- Create during the thermal vacuum testing the qualification temperature map with gradients along the APM. From of 200oC to 70oC.- Test in that conditions the radio frequency and pointing performances adding also high RF power to check the power handling and self-heating of the rotary joint.- Test in life up to 12000 equivalent APM revolutions, that is 14.3 million motor revolutions in different thermal conditions.- Measure low thermal distortion of the mechanical chain, being at the same time insulated from external environment and interfaces (55 arcsec pointing error)- Perform deployment of large items guaranteeing during the process low humidity, below 5% to protect dry lubrication- Verify stability with representative inertia of large boom or reflector 20 Kgm2.

  17. Relationship between relative humidity and the dew point ...

    African Journals Online (AJOL)

    This research was aimed at determining the relationship between relative humidity and the dew point temperature in Benin City, Edo State, Nigeria. The dew point temperature was approximated from the measured air temperature and relative humidity with the aid of a currently self-designed weather monitoring system.

  18. Research on an uplink carrier sense multiple access algorithm of large indoor visible light communication networks based on an optical hard core point process.

    Science.gov (United States)

    Nan, Zhufen; Chi, Xuefen

    2016-12-20

    The IEEE 802.15.7 protocol suggests that it could coordinate the channel access process based on the competitive method of carrier sensing. However, the directionality of light and randomness of diffuse reflection would give rise to a serious imperfect carrier sense (ICS) problem [e.g., hidden node (HN) problem and exposed node (EN) problem], which brings great challenges in realizing the optical carrier sense multiple access (CSMA) mechanism. In this paper, the carrier sense process implemented by diffuse reflection light is modeled as the choice of independent sets. We establish an ICS model with the presence of ENs and HNs for the multi-point to multi-point visible light communication (VLC) uplink communications system. Considering the severe optical ICS problem, an optical hard core point process (OHCPP) is developed, which characterizes the optical CSMA for the indoor VLC uplink communications system. Due to the limited coverage of the transmitted optical signal, in our OHCPP, the ENs within the transmitters' carrier sense region could be retained provided that they could not corrupt the ongoing communications. Moreover, because of the directionality of both light emitting diode (LED) transmitters and receivers, theoretical analysis of the HN problem becomes difficult. In this paper, we derive the closed-form expression for approximating the outage probability and transmission capacity of VLC networks with the presence of HNs and ENs. Simulation results validate the analysis and also show the existence of an optimal physical carrier-sensing threshold that maximizes the transmission capacity for a given emission angle of LED.

  19. Design, Results, Evolution and Status of the ATLAS Simulation at Point1 Project

    Science.gov (United States)

    Ballestrero, S.; Batraneanu, S. M.; Brasolin, F.; Contescu, C.; Fazio, D.; Di Girolamo, A.; Lee, C. J.; Pozo Astigarraga, M. E.; Scannicchio, D. A.; Sedov, A.; Twomey, M. S.; Wang, F.; Zaytsev, A.

    2015-12-01

    During the LHC Long Shutdown 1 (LSI) period, that started in 2013, the Simulation at Point1 (Sim@P1) project takes advantage, in an opportunistic way, of the TDAQ (Trigger and Data Acquisition) HLT (High-Level Trigger) farm of the ATLAS experiment. This farm provides more than 1300 compute nodes, which are particularly suited for running event generation and Monte Carlo production jobs that are mostly CPU and not I/O bound. It is capable of running up to 2700 Virtual Machines (VMs) each with 8 CPU cores, for a total of up to 22000 parallel jobs. This contribution gives a review of the design, the results, and the evolution of the Sim@P1 project, operating a large scale OpenStack based virtualized platform deployed on top of the ATLAS TDAQ HLT farm computing resources. During LS1, Sim@P1 was one of the most productive ATLAS sites: it delivered more than 33 million CPU-hours and it generated more than 1.1 billion Monte Carlo events. The design aspects are presented: the virtualization platform exploited by Sim@P1 avoids interferences with TDAQ operations and it guarantees the security and the usability of the ATLAS private network. The cloud mechanism allows the separation of the needed support on both infrastructural (hardware, virtualization layer) and logical (Grid site support) levels. This paper focuses on the operational aspects of such a large system during the upcoming LHC Run 2 period: simple, reliable, and efficient tools are needed to quickly switch from Sim@P1 to TDAQ mode and back, to exploit the resources when they are not used for the data acquisition, even for short periods. The evolution of the central OpenStack infrastructure is described, as it was upgraded from Folsom to the Icehouse release, including the scalability issues addressed.

  20. Practical Design of Delta-Sigma Multiple Description Audio Coding

    DEFF Research Database (Denmark)

    Leegaard, Jack Højholt; Østergaard, Jan; Jensen, Søren Holdt

    2014-01-01

    It was recently shown that delta-sigma quantization (DSQ) can be used for optimal multiple description (MD) coding of Gaussian sources. The DSQ scheme combined oversampling, prediction, and noise-shaping in order to trade off side distortion for central distortion in MD coding. It was shown that ...