Non-infectious plasmid engineered to simulate multiple viral threat agents.

Science.gov (United States)

Carrera, Monica; Sagripanti, Jose-Luis

2009-07-01

The aim of this study was to design and construct a non-virulent simulant to replace several pathogenic viruses in the development of detection and identification methods in biodefense. A non-infectious simulant was designed and engineered to include the nucleic acid signature of VEEV (Venezuelan Equine Encephalitis virus), Influenza virus, Rift Valley Fever virus, Machupo virus, Lassa virus, Yellow Fever virus, Ebola virus, Eastern Equine Encephalitis virus, Junin virus, Marburg virus, Dengue virus, and Crimean-Congo virus, all in a single construct. The nucleic acid sequences of all isolates available for each virus species were aligned using ClustalW software in order to obtain conserved regions of the viral genomes. Specific primers were designed to permit the identification and differentiation between viral threat agents. A chimera of 3143 base pairs was engineered to produce 13 PCR amplicons of different sizes. PCR amplification of the simulant with virus-specific primers revealed products of the predicted length, in bands of similar intensity, and without detectable unspecific products by electrophoresis analysis. The simulant described could reduce the need to use infectious viruses in the development of detection and diagnostic methods, and could also be useful as a non-virulent positive control in nucleic acid-based tests against biological threat agents.

Systems integration: an effective and innovative response to emerging biological threats.

Science.gov (United States)

House, Robert V

2007-04-20

A rapid and effective development of vaccines and other prophylactics, as well as novel therapeutics, against emerging threats requires the development and implementation of novel strategies. One such strategy is the integrator approach. This approach utilizes an integrated development team comprising expertise in program management, scientific management, clinical research, preclinical/nonclinical development, manufacturing, testing, risk management, quality assurance, and regulatory strategy and compliance. Key to the success of this approach is the successful management of subcontracted work, as well as the seamless integration of multiple systems and data inputs into a coherent development plan.

Integration of multiple cues allows threat-sensitive anti-intraguild predator responses in predatory mites

Science.gov (United States)

Walzer, Andreas; Schausberger, Peter

2013-01-01

Intraguild (IG) prey is commonly confronted with multiple IG predator species. However, the IG predation (IGP) risk for prey is not only dependent on the predator species, but also on inherent (intraspecific) characteristics of a given IG predator such as its life-stage, sex or gravidity and the associated prey needs. Thus, IG prey should have evolved the ability to integrate multiple IG predator cues, which should allow both inter- and intraspecific threat-sensitive anti-predator responses. Using a guild of plant-inhabiting predatory mites sharing spider mites as prey, we evaluated the effects of single and combined cues (eggs and/or chemical traces left by a predator female on the substrate) of the low risk IG predator Neoseiulus californicus and the high risk IG predator Amblyseius andersoni on time, distance and path shape parameters of the larval IG prey Phytoseiulus persimilis. IG prey discriminated between traces of the low and high risk IG predator, with and without additional presence of their eggs, indicating interspecific threat-sensitivity. The behavioural changes were manifest in distance moved, activity and path shape of IG prey. The cue combination of traces and eggs of the IG predators conveyed other information than each cue alone, allowing intraspecific threat-sensitive responses by IG prey apparent in changed velocities and distances moved. We argue that graded responses to single and combined IG predator cues are adaptive due to minimization of acceptance errors in IG prey decision making. PMID:23750040

International forum on nuclear and biological decommissioning: Management of global security threats

International Nuclear Information System (INIS)

Aslanian, G.; Kouzminov, V.; Martellini, M.; Santesso, R.

1998-01-01

The Forum on Nuclear and Biological Decommissioning: Management of Global Security Threats was organized by the Landau Network-Centro Volta (LNCV) with the support of the UNESCO Venice Office, the Italian Ministry of Foreign Affairs, the Italian National Board for Alternative Energy Sources (ENEA), the Lombardy Region and the Municipality of Como. Subjects dealt with at the conference included the reconversion of nuclear and biological military equipment produced in the 50 years of the Cold War period and the effects of radio contamination on the environment and on human life. This conference was the most recent of a number of initiatives on reconversion organized in collaboration with the UNESCO Venice Office. The issues dealt with at the conference will be among the subjects for discussion at the UNESCO International School Science for Peace, which will be set up at the 'A. Volta' Center for Scientific Culture

Prototyping of CBRN threat assessment system. Phase 1

International Nuclear Information System (INIS)

Ina, Shinichiro; Suzuki, Tomoyuki; Maeno, Akihiro; Sakaue, Motoki

2015-01-01

Recently, chemical, biological, radiological and nuclear threats, that is, CBRN threats have emerged. In order to support the Japan Self Defense Forces unit coping with the CBRN threats, it is important to take measures against these invisible threats. Our CBRN threat assessment system will make invisible CBRN threats visible. This report describes a prototyping of the CBRN threat assessment system (PHASE 1) carried out from fiscal year 2012-2014. (author)

Major issues in threat analysis and resolving such problems: an addendum to the GAP analysis

Directory of Open Access Journals (Sweden)

T.D. Surasinghe

2012-04-01

Full Text Available Identification of regions that warrant conservation attention is a top priority among global environmental concerns. Conventionally, this objective was achieved via recognizing natural landscapes based on the number of IUCN Red Listed species, percentage of endemism and species diversity. A recent innovation in conservation biology is the use of GIS-based threat analysis models to identify key areas of conservation importance. Compared with GAP Analysis, which only identifies biodiversity-rich unprotected lands, threat analysis serves as a rigorous tool in conservation planning which specifically recognizes threats and habitat suitability to different taxa based on a spatially-explicit analysis. Threat analysis is a highly flexible process which involves building up a model with multiple independent (without autocorrelations variables that both positively and negatively affect distribution and population persistence of a concerned species. Parameters include rate of land-use change, population density, population growth rate, land management regimes, protection status, habitat suitability and land stewardship. Threat analysis models can be used to understand the current status of a particular species (or a community and can be used to project future trends about the species under consideration. This publication provides an overview of uses of GIS-based threat analyses in conservation biology and provides insights on the limitations of these models and the directions that should be taken in future.

On the implementation of the Biological Threat Reduction Program in the Republic of Uzbekistan

Science.gov (United States)

Tuychiev, Laziz; Madaminov, Marifjon

2013-01-01

Objective To review the implementation of the Biological Threat Reduction Program (BTRP) of the U.S. Defense Threat Reduction Agency in the Republic of Uzbekistan since 2004. Introduction The Biological Threat Reduction Program (BTRP) has been being implemented in the Republic of Uzbekistan since 2004 within the framework of the Agreement between the Government of the Republic of Uzbekistan and the Government of the United States of America Concerning Cooperation in the Area of the Promotion of Defense Relations and the Prevention of Proliferation of Weapons of Mass Destruction of 06.05.2001. Threat agent detection and response activities that target a list of especially dangerous pathogens are being carried out under the BTRP within the health care system of Uzbekistan. This presentation reviews some of the achievements of the program to date. Results BTRP, in partnership with the Government of Uzbekistan, has funded the establishment of five Regional Diagnostic Laboratories (RDL) and ten Epidemiological Support Units (ESU), operated by the Ministry of Health of Uzbekistan, which are intended to improve the diagnosis of quarantine and especially dangerous infections, and to ensure timely preventive and anti-epidemic measures. RDLs provide a high level of biosafety and biosecurity to conduct rapid laboratory diagnostics (PCR, ELISA) of especially dangerous infections. RDLs are equipped with up-to-date diagnostic laboratory equipment that conforms to internationals standards, as well as with all necessary consumables. Personnel of RDLs have been appropriately trained in epidemiology, clinical and diagnostic techniques for especially dangerous infections, including such state-of-the-art techniques as rapid PCR and ELISA diagnostics, as well as in work and equipment operation safety regulations. Epidemiological Support Units (ESU) have been established on the basis of the Especially Dangerous Infections Divisions of Oblast, city and Rayon Centers for State Sanitary

Gender-, Race-, and Income-Based Stereotype Threat: The Effects of Multiple Stigmatized Aspects of Identity on Math Performance and Working Memory Function

Science.gov (United States)

Tine, Michele; Gotlieb, Rebecca

2013-01-01

This study compared the relative impact of gender-, race-, and income-based stereotype threat and examined if individuals with multiple stigmatized aspects of identity experience a larger stereotype threat effect on math performance and working memory function than people with one stigmatized aspect of identity. Seventy-one college students of the…

Chemistry and biology by new multiple choice

International Nuclear Information System (INIS)

Seo, Hyeong Seok; Kim, Seong Hwan

2003-02-01

This book is divided into two parts, the first part is about chemistry, which deals with science of material, atom structure and periodic law, chemical combination and power between molecule, state of material and solution, chemical reaction and an organic compound. The second part give description of biology with molecule and cell, energy in cells and chemical synthesis, molecular biology and heredity, function on animal, function on plant and evolution and ecology. This book has explanation of chemistry and biology with new multiple choice.

Concealed Threat Detection at Multiple Frames-per-second

Energy Technology Data Exchange (ETDEWEB)

Chang, J T

2005-11-08

In this LDRD project, our research purpose is to investigate the science and technology necessary to enable real-time array imaging as a rapid way to detect hidden threats through obscurants such as smoke, fog, walls, doors, and clothing. The goal of this research is to augment the capabilities of protective forces in concealed threat detection. In the current context, threats include people as well as weapons. In most cases, security personnel must make very fast assessments of a threat based upon limited amount of data. Among other attributes, UWB has been shown and quantified to penetrate and propagate through many materials (wood, some concretes, non-metallic building materials, some soils, etc.) while maintaining high range resolution. We have build collaborations with university partners and government agencies. We have considered the impact of psychometrics on target recognition and identification. Specifically we have formulated images in real-time that will engage the user's vision system in a more active way to enhance image interpretation capabilities. In this project, we are researching the use of real time (field programmable gate arrays) integrated with high resolution (cm scale), ultra wide band (UWB) electromagnetic signals for imaging personnel through smoke and walls. We evaluated the ability of real-time UWB imaging for detecting smaller objects, such as concealed weapons that are carried by the obscured personnel. We also examined the cognitive interpretation process of real time UWB electromagnetic images.

Managing threats from emerging technologies: can safeguards show the way?

International Nuclear Information System (INIS)

Leffer, Teri N.

2014-01-01

The system of international nuclear safeguards implemented by the International Atomic Energy Agency (IAEA) is primarily a means of verification of states’ commitments under various legal instruments, principally the Nuclear Non‑Proliferation Treaty (NPT), to utilize controlled nuclear fission for peaceful purposes only. However, the safeguards system can also be seen as a mechanism through which states acted to reduce the threat posed by a new technology that had a transformative impact on existing national security paradigms when it emerged in the twentieth century. In the twenty‑first century, new technologies with equally profound national security implications are emerging. These include biotechnology and synthetic biology, nano technology, information technology, cognitive science, robotics and artificial intelligence. Throughout its history, the safeguards system has evolved to accommodate new technologies, new undertakings and new threats. Because multiple emerging technologies now constitute potential national security threats, it is appropriate to consider whether and how the lessons and successes of the safeguards system, including its capacity to evolve in response to changing requirements, could be leveraged to mitigate the threat posed by these new technologies. This paper addresses the possibility of re‑imagining safeguards in a way that makes them applicable to a broader range of technology‑based threats without compromising their effectiveness for their original purpose.

The nuclear threat and the Nuclear Threat Initiative

International Nuclear Information System (INIS)

Curtis, Charles

2001-01-01

Full text: President and chief operating officer of the Nuclear Threat Initiative (NTI), was invited by the IAEA Director General to speak about NTI and its mission at the IAEA Safeguards Symposium. Established by CNN founder Ted Turner and former U.S. Senator Sam Nunn, NTI is a charitable organization working to strengthen global security by reducing the risk of use and preventing the spread of nuclear, biological and chemical weapons. The foundation is global, concentrating not just on the United States, Russia, and other nations of the former Soviet Union, but also on those regions of greatest proliferation concern in Asia and the Middle East. NTI is working to close what it perceives as an increasingly dangerous gap between the threat from nuclear, biological and chemical weapons and the global response. NTI is supported by a pledge from Mr. Turner of at least $250 million over five years, among the largest sums any private individual has ever invested in these security issues. NTI's Board of Directors, an international team of experienced and knowledgeable experts, determines the overall direction of the foundation. (author)

E-War : an early warning and response methodology for buildings at risk to chemical and biological threats

Energy Technology Data Exchange (ETDEWEB)

Rastan, S.; Kozinski, J. [McGill Univ., Montreal, PQ (Canada); Foo, S.; Morofsky, E. [Public Works and Government Services, Ottawa, ON (Canada). Indoor Environments and Healthy Buildings

2004-07-01

Several government departments, academic institutions and private firms have collaborated on a research project to develop an Early Warning and Response (e-WAR) method to protect occupants in high-risk public buildings from chemical and biological threats. The project involves a heat, ventilation and air conditioning (HVAC) based monitoring system equipped with photo ionization and laser particle counter technologies to characterize baseline airborne concentrations. E-WAR recognizes out-of-norm events and instantly triggers a set of just-in-case (JIC) filtration, in-duct neutralization and decontamination responses to reduce the dispersion of toxic airborne materials within the building. The proposed system reduced the severity of any potential threat, as well as the cost of remediation. A scale model of the proposed system has been designed and developed. 45 refs., 1 tab., 1 fig.

The Nature of the Bioterrorism Threat

Energy Technology Data Exchange (ETDEWEB)

Regens, J. L.

2003-02-25

This analysis provides an overview of the nature of the bioterrorism threat. It identifies potential CDC Class A biological agents that are likely candidates for use in a terrorist incident and describes the known sources of vulnerability. The paper also summarizes S&T resources/needs and assesses response options for achieving effective biodefense against terrorist threats.

Biological Threats Detection Technologies

International Nuclear Information System (INIS)

Bartoszcze, M.

2007-01-01

Among many decisive factors, which can have the influence on the possibility of decreases the results of use biological agents should be mentioned obligatory: rapid detection and identification of biological factor used, the proper preventive treatment and the medical management. The aims of identification: to identify the factor used, to estimate the area of contamination, to evaluate the possible countermeasure efforts (antibiotics, disinfectants) and to assess the effectiveness of the decontamination efforts (decontamination of the persons, equipment, buildings, environment etc.). The objects of identification are: bacteria and bacteria's spores, viruses, toxins and genetically modified factors. The present technologies are divided into: based on PCR techniques (ABI PRISM, APSIS, BIOVERIS, RAPID), immuno (BADD, RAMP, SMART) PCR and immuno techniques (APDS, LUMINEX) and others (BDS2, LUNASCAN, MALDI). The selected technologies assigned to field conditions, mobile and stationary laboratories will be presented.(author)

Inferring the nature of anthropogenic threats from long-term abundance records.

Science.gov (United States)

Shoemaker, Kevin T; Akçakaya, H Resit

2015-02-01

Diagnosing the processes that threaten species persistence is critical for recovery planning and risk forecasting. Dominant threats are typically inferred by experts on the basis of a patchwork of informal methods. Transparent, quantitative diagnostic tools would contribute much-needed consistency, objectivity, and rigor to the process of diagnosing anthropogenic threats. Long-term census records, available for an increasingly large and diverse set of taxa, may exhibit characteristic signatures of specific threatening processes and thereby provide information for threat diagnosis. We developed a flexible Bayesian framework for diagnosing threats on the basis of long-term census records and diverse ancillary sources of information. We tested this framework with simulated data from artificial populations subjected to varying degrees of exploitation and habitat loss and several real-world abundance time series for which threatening processes are relatively well understood: bluefin tuna (Thunnus maccoyii) and Atlantic cod (Gadus morhua) (exploitation) and Red Grouse (Lagopus lagopus scotica) and Eurasian Skylark (Alauda arvensis) (habitat loss). Our method correctly identified the process driving population decline for over 90% of time series simulated under moderate to severe threat scenarios. Successful identification of threats approached 100% for severe exploitation and habitat loss scenarios. Our method identified threats less successfully when threatening processes were weak and when populations were simultaneously affected by multiple threats. Our method selected the presumed true threat model for all real-world case studies, although results were somewhat ambiguous in the case of the Eurasian Skylark. In the latter case, incorporation of an ancillary source of information (records of land-use change) increased the weight assigned to the presumed true model from 70% to 92%, illustrating the value of the proposed framework in bringing diverse sources of

Meeting the challenge of interacting threats in freshwater ecosystems: A call to scientists and managers

Directory of Open Access Journals (Sweden)

Laura S. Craig

2017-12-01

Full Text Available Human activities create threats that have consequences for freshwater ecosystems and, in most watersheds, observed ecological responses are the result of complex interactions among multiple threats and their associated ecological alterations. Here we discuss the value of considering multiple threats in research and management, offer suggestions for filling knowledge gaps, and provide guidance for addressing the urgent management challenges posed by multiple threats in freshwater ecosystems. There is a growing literature assessing responses to multiple alterations, and we build off this background to identify three areas that require greater attention: linking observed alterations to threats, understanding when and where threats overlap, and choosing metrics that best quantify the effects of multiple threats. Advancing science in these areas will help us understand existing ecosystem conditions and predict future risk from multiple threats. Because addressing the complex issues and novel ecosystems that arise from the interaction of multiple threats in freshwater ecosystems represents a significant management challenge, and the risks of management failure include loss of biodiversity, ecological goods, and ecosystem services, we also identify actions that could improve decision-making and management outcomes. These actions include drawing insights from management of individual threats, using threat attributes (e.g., causes and spatio-temporal dynamics to identify suitable management approaches, testing management strategies that are likely to be successful despite uncertainties about the nature of interactions among threats, avoiding unintended consequences, and maximizing conservation benefits. We also acknowledge the broadly applicable challenges of decision-making within a socio-political and economic framework, and suggest that multidisciplinary teams will be needed to innovate solutions to meet the current and future challenge of interacting

Meeting the challenge of interacting threats in freshwater ecosystems: A call to scientists and managers

Science.gov (United States)

Craig, Laura S.; Olden, Julian D.; Arthington, Angela; Entrekin, Sally; Hawkins, Charles P.; Kelly, John J.; Kennedy, Theodore A.; Maitland, Bryan M.; Rosi, Emma J.; Roy, Allison; Strayer, David L.; Tank, Jennifer L.; West, Amie O.; Wooten, Matthew S.

2017-01-01

Human activities create threats that have consequences for freshwater ecosystems and, in most watersheds, observed ecological responses are the result of complex interactions among multiple threats and their associated ecological alterations. Here we discuss the value of considering multiple threats in research and management, offer suggestions for filling knowledge gaps, and provide guidance for addressing the urgent management challenges posed by multiple threats in freshwater ecosystems. There is a growing literature assessing responses to multiple alterations, and we build off this background to identify three areas that require greater attention: linking observed alterations to threats, understanding when and where threats overlap, and choosing metrics that best quantify the effects of multiple threats. Advancing science in these areas will help us understand existing ecosystem conditions and predict future risk from multiple threats. Because addressing the complex issues and novel ecosystems that arise from the interaction of multiple threats in freshwater ecosystems represents a significant management challenge, and the risks of management failure include loss of biodiversity, ecological goods, and ecosystem services, we also identify actions that could improve decision-making and management outcomes. These actions include drawing insights from management of individual threats, using threat attributes (e.g., causes and spatio-temporal dynamics) to identify suitable management approaches, testing management strategies that are likely to be successful despite uncertainties about the nature of interactions among threats, avoiding unintended consequences, and maximizing conservation benefits. We also acknowledge the broadly applicable challenges of decision-making within a socio-political and economic framework, and suggest that multidisciplinary teams will be needed to innovate solutions to meet the current and future challenge of interacting threats in

The indoor as a scene for biological threats

DEFF Research Database (Denmark)

Storgaard, Kresten; Gunnarsen, Lars; Bräuner, Elvira

2014-01-01

The paper presents the result of involving users in developing a user-friendly device for easy and fast detection of bio-threats in indoor settings. Bio-protect is a project supported by the European Commission, with the concept of developing a fast-alert, mobile, easy-to-use device to detect and...

'NRBC' threat: is this concept still valid?

International Nuclear Information System (INIS)

Lacronique, J.F.

2006-01-01

About 10 years ago, after the Sarin attack in Tokyo, the world discover that terrorists could use again radio-nuclear, chemical or biological agents to launch attacks, just to cause terror and disruption of western economies. This has forged the acronym 'NRBC'. In terms of likelihood, nuclear and radiological attacks could be considered among the most easy to prepare, and some possible acts are listed in this paper. A considerable amount of work has been prepared for the preparedness against radio-nuclear attacks, during the last 3 years, by World Health Organization (WHO), International Atomic Energy Agency (IAEA), the Atomic Energy Agency (AEN) as well as by the International Commission of Radio Protection (ICRP). A series of documents have been issued from international cooperation. These documents shows specificities to the R/N threat in terms of health consequences, that make this threat less prone to international cooperative efforts than biological threats. In addition, the Ministers of Health of the G7 countries have created an 'Global Health Security Initiative' (GHSI) in 2002 to anticipate crisis such as the anthrax problem, or other possible NRBC threats

Web threat and its implication for E-business in Nigeria ...

African Journals Online (AJOL)

Web threat is any threat that uses the internet to facilitate identity theft , fraud, espionage and intelligence gathering. Web -based vulnerabilities now outnumber traditional computer security concerns. Such threats use multiple types of malware and fraud, all of which utilize HTTP or HTTPS protocols, but may also employ ...

Stereotype threat affects financial decision making.

Science.gov (United States)

Carr, Priyanka B; Steele, Claude M

2010-10-01

The research presented in this article provides the first evidence that one's decision making can be influenced by concerns about stereotypes and the devaluation of one's identity. Many studies document gender differences in decision making, and often attribute these differences to innate and stable factors, such as biological and hormonal differences. In three studies, we found that stereotype threat affected decision making and led to gender differences in loss-aversion and risk-aversion behaviors. In Study 1, women subjected to stereotype threat in academic and business settings were more loss averse than both men and women who were not facing the threat of being viewed in light of negative stereotypes. We found no gender differences in loss-aversion behavior in the absence of stereotype threat. In Studies 2a and 2b, we found the same pattern of effects for risk-aversion behavior that we had observed for loss-aversion behavior. In addition, in Study 2b, ego depletion mediated the effects of stereotype threat on women's decision making. These results suggest that individuals' decision making can be influenced by stereotype concerns.

A review of multi-threat medical countermeasures against chemical warfare and terrorism.

Science.gov (United States)

Cowan, Fred M; Broomfield, Clarence A; Stojiljkovic, Milos P; Smith, William J

2004-11-01

The Multi-Threat Medical Countermeasure (MTMC) hypothesis has been proposed with the aim of developing a single countermeasure drug with efficacy against different pathologies caused by multiple classes of chemical warfare agents. Although sites and mechanisms of action and the pathologies caused by different chemical insults vary, common biochemical signaling pathways, molecular mediators, and cellular processes provide targets for MTMC drugs. This article will review the MTMC hypothesis for blister and nerve agents and will expand the scope of the concept to include other chemicals as well as briefly consider biological agents. The article will also consider how common biochemical signaling pathways, molecular mediators, and cellular processes that contribute to clinical pathologies and syndromes may relate to the toxicity of threat agents. Discovery of MTMC provides the opportunity for the integration of diverse researchers and clinicians, and for the exploitation of cutting-edge technologies and drug discovery. The broad-spectrum nature of MTMC can augment military and civil defense to combat chemical warfare and chemical terrorism.

The bioscience revolution & the biological weapons threat: levers & interventions

Directory of Open Access Journals (Sweden)

Martin Greg

2009-02-01

Full Text Available Abstract In December 2008, the US Commission on the Prevention of Weapons of Mass Destruction Proliferation and Terrorism, released a report, World At Risk. The Report points to the fact that, not only is the use of a weapon of mass destruction in a terrorist attack before the end of 2013, more likely than not, but also to the fact that terrorists are more likely to be able to obtain and use biological weapons than nuclear. This paper examines the recommendations of the report in the context of the historic and geopolitical changes, in particular globalization. The authors highlight the "dual-use" dilemma, as described in the report, as the paradoxical use of technology developed for the benefit of mankind being used for sinister purposes. The mitigation of such a threat lies in broad stakeholder involvement and cooperation, including non-state actors, governments and the bio-tech industry itself. The importance of vigilance measures within the life science community is emphasized and, the authors propose, could include a web-based didactic course in bioterrorism and weapons of mass destruction identification. The site could outline safety protocols, have detailed disaster management tutorials, and could be specifically tailored for different subsets of industry and health professionals. The paper concludes with an endorsement of a multi-pronged approach including strong international guidelines and intelligence cooperation and preparatory measures such as the wide-spread use of detection systems as well as diagnostic decision support systems for bioterrorism detection at the local level.

Airborne Particulate Threat Assessment

Energy Technology Data Exchange (ETDEWEB)

Patrick Treado; Oksana Klueva; Jeffrey Beckstead

2008-12-31

Aerosol threat detection requires the ability to discern between threat agents and ambient background particulate matter (PM) encountered in the environment. To date, Raman imaging technology has been demonstrated as an effective strategy for the assessment of threat agents in the presence of specific, complex backgrounds. Expanding our understanding of the composition of ambient particulate matter background will improve the overall performance of Raman Chemical Imaging (RCI) detection strategies for the autonomous detection of airborne chemical and biological hazards. Improving RCI detection performance is strategic due to its potential to become a widely exploited detection approach by several U.S. government agencies. To improve the understanding of the ambient PM background with subsequent improvement in Raman threat detection capability, ChemImage undertook the Airborne Particulate Threat Assessment (APTA) Project in 2005-2008 through a collaborative effort with the National Energy Technology Laboratory (NETL), under cooperative agreement number DE-FC26-05NT42594. During Phase 1 of the program, a novel PM classification based on molecular composition was developed based on a comprehensive review of the scientific literature. In addition, testing protocols were developed for ambient PM characterization. A signature database was developed based on a variety of microanalytical techniques, including scanning electron microscopy, FT-IR microspectroscopy, optical microscopy, fluorescence and Raman chemical imaging techniques. An automated particle integrated collector and detector (APICD) prototype was developed for automated collection, deposition and detection of biothreat agents in background PM. During Phase 2 of the program, ChemImage continued to refine the understanding of ambient background composition. Additionally, ChemImage enhanced the APICD to provide improved autonomy, sensitivity and specificity. Deliverables included a Final Report detailing our

Towards Integration of Biological and Physiological Functions at Multiple Levels

Directory of Open Access Journals (Sweden)

Taishin eNomura

2010-12-01

Full Text Available An aim of systems physiology today can be stated as to establish logical and quantitative bridges between phenomenological attributes of physiological entities such as cells and organs and physical attributes of biological entities, i.e., biological molecules, allowing us to describe and better understand physiological functions in terms of underlying biological functions. This article illustrates possible schema that can be used for promoting systems physiology by integrating quantitative knowledge of biological and physiological functions at multiple levels of time and space with the use of information technology infrastructure. Emphasis will be made for systematic, modular, hierarchical, and standardized descriptions of mathematical models of the functions and advantages for the use of them.

Sources and basic threats of biological safety

International Nuclear Information System (INIS)

Nazarova, O.D.

2010-01-01

Full text: Biological safety of any state is connected with development of its public protection against biological weapons and opportunity to prevent bio terrorist attacks. That's why in modern social-economic and geo-political conditions, the problem of biological safety strengthening become significant, which is connected with migration process globalization, development of bio-technology and dramatically increased risk of pathogenic germ infections proliferation, which can be used as biological weapon. Despite of undertaken efforts by world community on full prohibition of biological weapon, its proliferation in the world still takes place. Biology revolution during second and third millennium lead to development not only biotechnology but new achievements in medicine, agriculture and other fields of economy, but also created scientific and research preconditions for development of advanced biological means of mass destruction, that make it more attractive for achieving superiority and assigned targets: low developments costs, opportunity to create it by one small laboratory with two-three high qualified specialists bio technologists; tremendous impact effect: one substance gram can contain from one till one hundreds quintillions (10"1"8 - 10"2"0) active pathogen molecules and in case if they belong to amplificated RNA and DNA, each molecule getting to organism, will multiply and contaminate environment (the last one is its principal difference from chemical weapon); bypass of organism immunological barriers and specific vaccinations; unusual clinic finding, hard diagnosis; weakness of traditional medications and treatment methods; lack of material destruction; opportunity of tight-lipped developments; opportunity of tight-lipped application; opportunity of delayed effect; opportunity of selective influence on specific population (by use of genetic, climatic and cultural specifications of race, nations and nationalities). Above mentioned specifications create

Habitat preferences and conservation threats to Black-necked Cranes wintering in Bhutan.

Science.gov (United States)

Namgay, Rinchen; Wangchuk, Sangay

2016-01-01

Black-necked Crane (Grus nigricollis) is a vulnerable Red list species whose populations are declining. However, little is known about Black-necked Cranes' habitat requirements or the causes of their population decline. We identified Black-necked Cranes' winter roost and foraging preferences of Black-necked Cranes in Bhutan during the winter of 2013-2014. Black-necked Cranes' roosts were recorded using Garmin GPSmap 60CSx, while foraging preferences and threats to the birds were identified based on a survey of household heads (n = 107) residing within a 3 km radius of roost sites. We grouped the threats identified by the communities into four major categories, viz. biological, social, political and natural threats based on the relevance. Of the four major threats, communities residing within the roosting and foraging habitat of the Black-necked Crane reported biological threat as major. Biological threats as reported by communities include loss of habitat, food shortage and competition from other animals. We recommend the present roosting areas be designated as part of the conservation areas for Black-necked Crane wintering in Bumthang district. In addition to preserving these areas, government should also encourage farming in foraging habitats of Black-necked Crane, because they mainly feed on barley, wheat, paddy, potatoes and buckwheat, besides roots, tubers and insects in the wetlands.

Automated recognition and tracking of aerosol threat plumes with an IR camera pod

Science.gov (United States)

Fauth, Ryan; Powell, Christopher; Gruber, Thomas; Clapp, Dan

2012-06-01

Protection of fixed sites from chemical, biological, or radiological aerosol plume attacks depends on early warning so that there is time to take mitigating actions. Early warning requires continuous, autonomous, and rapid coverage of large surrounding areas; however, this must be done at an affordable cost. Once a potential threat plume is detected though, a different type of sensor (e.g., a more expensive, slower sensor) may be cued for identification purposes, but the problem is to quickly identify all of the potential threats around the fixed site of interest. To address this problem of low cost, persistent, wide area surveillance, an IR camera pod and multi-image stitching and processing algorithms have been developed for automatic recognition and tracking of aerosol plumes. A rugged, modular, static pod design, which accommodates as many as four micro-bolometer IR cameras for 45deg to 180deg of azimuth coverage, is presented. Various OpenCV1 based image-processing algorithms, including stitching of multiple adjacent FOVs, recognition of aerosol plume objects, and the tracking of aerosol plumes, are presented using process block diagrams and sample field test results, including chemical and biological simulant plumes. Methods for dealing with the background removal, brightness equalization between images, and focus quality for optimal plume tracking are also discussed.

Assessing the Biological Threat Posed by Suicide Bombers

Science.gov (United States)

2016-02-01

the test by about 350’, it is clear some aerosol particles “ surfed ” the shockwave from the blast and were carried a distance upwind. Had the sampling...projectiles implantation in victims of suicide bombings and implications for health and emergency care provideres: the 7/7 experience, Ann R Coll Surg Engl...Ebola in East Africa and Implications for Global Health and Security, Global Policy 2013. (8) Ustun, C.; Ozgurler, O., Ebola: A Significant Threat as

Using expert opinion surveys to rank threats to endangered species: a case study with sea turtles.

Science.gov (United States)

Donlan, C Josh; Wingfield, Dana K; Crowder, Larry B; Wilcox, Chris

2010-12-01

Little is known about how specific anthropogenic hazards affect the biology of organisms. Quantifying the effect of regional hazards is particularly challenging for species such as sea turtles because they are migratory, difficult to study, long lived, and face multiple anthropogenic threats. Expert elicitation, a technique used to synthesize opinions of experts while assessing uncertainty around those views, has been in use for several decades in the social science and risk assessment sectors. We conducted an internet-based survey to quantify expert opinion on the relative magnitude of anthropogenic hazards to sea turtle populations at the regional level. Fisheries bycatch and coastal development were most often ranked as the top hazards to sea turtle species in a geographic region. Nest predation and direct take followed as the second and third greatest threats, respectively. Survey results suggest most experts believe sea turtles are threatened by multiple factors, including substantial at-sea threats such as fisheries bycatch. Resources invested by the sea turtle community, however, appear biased toward terrestrial-based impacts. Results from the survey are useful for conservation planning because they provide estimates of relative impacts of hazards on sea turtles and a measure of consensus on the magnitude of those impacts among researchers and practitioners. Our survey results also revealed patterns of expert bias, which we controlled for in our analysis. Respondents with no experience with respect to a sea turtle species tended to rank hazards affecting that sea turtle species higher than respondents with experience. A more-striking pattern was with hazard-based expertise: the more experience a respondent had with a specific hazard, the higher the respondent scored the impact of that hazard on sea turtle populations. Bias-controlled expert opinion surveys focused on threatened species and their hazards can help guide and expedite species recovery plans. �

Evolution of natural history information in the 21st century – developing an integrated framework for biological and geographical data

Science.gov (United States)

Reusser, Deborah A.; Lee, Henry

2011-01-01

Threats to marine and estuarine species operate over many spatial scales, from nutrient enrichment at the watershed/estuarine scale to invasive species and climate change at regional and global scales. To help address research questions across these scales, we provide here a standardized framework for a biogeographical information system containing queriable biological data that allows extraction of information on multiple species, across a variety of spatial scales based on species distributions, natural history attributes and habitat requirements. As scientists shift from research on localized impacts on individual species to regional and global scale threats, macroecological approaches of studying multiple species over broad geographical areas are becoming increasingly important. The standardized framework described here for capturing and integrating biological and geographical data is a critical first step towards addressing these macroecological questions and we urge organizations capturing biogeoinformatics data to consider adopting this framework.

A Lesson Not to Be Learned? Understanding Stereotype Threat Does Not Protect Women from Stereotype Threat

Science.gov (United States)

Tomasetto, Carlo; Appoloni, Sara

2013-01-01

This research examines whether reading a text presenting scientific evidence concerning the phenomenon of stereotype threat improves or disrupts women's performance in a subsequent math task. In two experimental conditions participants (N=118 ) read a text summarizing an experiment in which stereotypes, and not biological differences, were shown…

Multiple social identities and stereotype threat: imbalance, accessibility, and working memory.

Science.gov (United States)

Rydell, Robert J; McConnell, Allen R; Beilock, Sian L

2009-05-01

In 4 experiments, the authors showed that concurrently making positive and negative self-relevant stereotypes available about performance in the same ability domain can eliminate stereotype threat effects. Replicating past work, the authors demonstrated that introducing negative stereotypes about women's math performance activated participants' female social identity and hurt their math performance (i.e., stereotype threat) by reducing working memory. Moving beyond past work, it was also demonstrated that concomitantly presenting a positive self-relevant stereotype (e.g., college students are good at math) increased the relative accessibility of females' college student identity and inhibited their gender identity, eliminating attendant working memory deficits and contingent math performance decrements. Furthermore, subtle manipulations in questions presented in the demographic section of a math test eliminated stereotype threat effects that result from women reporting their gender before completing the test. This work identifies the motivated processes through which people's social identities became active in situations in which self-relevant stereotypes about a stigmatized group membership and a nonstigmatized group membership were available. In addition, it demonstrates the downstream consequences of this pattern of activation on working memory and performance. Copyright (c) 2009 APA, all rights reserved.

Spatial congruence in language and species richness but not threat in the world's top linguistic hotspot.

Science.gov (United States)

Turvey, Samuel T; Pettorelli, Nathalie

2014-12-07

Languages share key evolutionary properties with biological species, and global-level spatial congruence in richness and threat is documented between languages and several taxonomic groups. However, there is little understanding of the functional connection between diversification or extinction in languages and species, or the relationship between linguistic and species richness across different spatial scales. New Guinea is the world's most linguistically rich region and contains extremely high biological diversity. We demonstrate significant positive relationships between language and mammal richness in New Guinea across multiple spatial scales, revealing a likely functional relationship over scales at which infra-island diversification may occur. However, correlations are driven by spatial congruence between low levels of language and species richness. Regional biocultural richness may have showed closer congruence before New Guinea's linguistic landscape was altered by Holocene demographic events. In contrast to global studies, we demonstrate a significant negative correlation across New Guinea between areas with high levels of threatened languages and threatened mammals, indicating that landscape-scale threats differ between these groups. Spatial resource prioritization to conserve biodiversity may not benefit threatened languages, and conservation policy must adopt a multi-faceted approach to protect biocultural diversity as a whole.

Different groups, different threats: a multi-threat approach to the experience of stereotype threats.

Science.gov (United States)

Shapiro, Jenessa R

2011-04-01

Two studies demonstrated that different negatively stereotyped groups are at risk for distinct forms of stereotype threats. The Multi-Threat Framework articulates six distinct stereotype threats and the unique constellations of variables (e.g., group identification, stereotype endorsement) that elicit each stereotype threat. Previous research suggests that different negatively stereotyped groups systematically vary across these stereotype threat elicitors; a pilot study confirms these differences. Across two studies, groups that tend to elicit low stereotype endorsement (religion, race/ethnicity, congenital blindness) were less likely to report experiencing self-as-source stereotype threats (stereotype threats requiring stereotype endorsement) and groups that tend to elicit low group identification (mental illness, obesity, blindness later in life) were less likely to report experiencing group-as-target stereotype threats (stereotype threats requiring group identification). This research suggests that traditional models may overlook the experiences of stereotype threats within some groups and that interventions tailored to address differences between stereotype threats will be most effective.

Status and threats analysis for the Florida manatee (Trichechus manatus latirostris), 2012

Science.gov (United States)

Runge, Michael C.; Langtimm, Catherine A.; Martin, Julien; Fonnesbeck, Christopher J.

2015-01-01

The endangered West Indian manatee (Trichechus manatus), especially the Florida subspecies (T. m. latirostris), has been the focus of conservation efforts and extensive research since its listing under the Endangered Species Act. On the basis of the best information available as of December 2012, the threats facing the Florida manatee were determined to be less severe than previously thought, either because the conservation efforts have been successful, or because our knowledge of the demographic effects of those threats is increased, or both. Using the manatee Core Biological Model, we estimated the probability of the Florida manatee population on either the Atlantic or Gulf coast falling below 500 adults in the next 150 years to be 0.92 percent. The primary threats remain watercraft-related mortality and long-term loss of warm-water habitat. Since 2009, however, there have been a number of unusual events that have not yet been incorporated into this analysis, including several severely cold winters, a severe red-tide die off, and substantial loss of seagrass habitat in Brevard County, Fla. Further, the version of the Core Biological Model used in 2012 makes a number of assumptions that are under investigation. A revision of the Core Biological Model and an update of this quantitative threats analysis are underway as of 2015.

A new threat to bees? Entomopathogenic nematodes used in biological pest control cause rapid mortality in Bombus terrestris

Directory of Open Access Journals (Sweden)

Alexandrea Dutka

2015-11-01

Full Text Available There is currently a great deal of concern about population declines in pollinating insects. Many potential threats have been identified which may adversely affect the behaviour and health of both honey bees and bumble bees: these include pesticide exposure, and parasites and pathogens. Whether biological pest control agents adversely affect bees has been much less well studied: it is generally assumed that biological agents are safer for wildlife than chemical pesticides. The aim of this study was to test whether entomopathogenic nematodes sold as biological pest control products could potentially have adverse effects on the bumble bee Bombus terrestris. One product was a broad spectrum pest control agent containing both Heterorhabditis sp. and Steinernema sp., the other product was specifically for weevil control and contained only Steinernema kraussei. Both nematode products caused ≥80% mortality within the 96 h test period when bees were exposed to soil containing entomopathogenic nematodes at the recommended field concentration of 50 nematodes per cm2 soil. Of particular concern is the fact that nematodes from the broad spectrum product could proliferate in the carcasses of dead bees, and therefore potentially infect a whole bee colony or spread to the wider environment.

Spatial Pattern Determination of Biodiversity Threats at Landscape Level (Case Study: Golestan Province)

OpenAIRE

R. Mirzaei; A. Esmaili-Sari; M. R. Hemami; H. R. Rezaei

2015-01-01

Mapping spatial patterns of potential biodiversity threats is one of the important steps for effective conservation planning and activities. To determine the spatial patterns of threats in Golestan province, 12 criteria in four main groups including structural (fractal coefficient of perimeter, circularity ratio of area, average slope), compositional aspects of biodiversity (presence of species at risk), non-biological threats (distance to city, distance to village, distance to road, distance...

Spatial Pattern Determination of Biodiversity Threats at Landscape Level (Case Study: Golestan Province

Directory of Open Access Journals (Sweden)

R. Mirzaei

2015-06-01

Full Text Available Mapping spatial patterns of potential biodiversity threats is one of the important steps for effective conservation planning and activities. To determine the spatial patterns of threats in Golestan province, 12 criteria in four main groups including structural (fractal coefficient of perimeter, circularity ratio of area, average slope, compositional aspects of biodiversity (presence of species at risk, non-biological threats (distance to city, distance to village, distance to road, distance to infrastructure, distance to agricultural land, soil pollution, risk of fire and isolation (Nearest Neighbor Index were used. These data layers were digitized in GIS environment and were weighted through Analytical Hierarchy Process. A weighted linear combination was then used to map the spatial pattern of biodiversity threats in the province. Compositional aspect (0.59, non-biological threats (0.23, isolation (0.11, and structural aspect (0.07 were relatively weighted in the order of importance. Central parts of the province and patches in the northern and southern parts were recognized to be more exposed to biodiversity threats. The central parts of the province were mostly threatened by urban, industrial, road and agricultural development, whereas the northern and southern parts were recognized as areas of conservation importance having a variety of threatened birds.

Glyphosate accumulation, translocation, and biological effects in Coffea arabica after single and multiple exposures

DEFF Research Database (Denmark)

Schrübbers, Lars Christoph; Valverde, Bernal E.; Strobel, Bjarne W.

2016-01-01

In perennial crops like coffee, glyphosate drift exposure can occur multiple times during its commercial life span. Due to limited glyphosate degradation in higher plants, a potential accumulation of glyphosate could lead to increased biological effects with increased exposure frequency....... In this study, we investigated glyphosate translocation over time, and its concentration and biological effects after single and multiple simulated spray-drift exposures. Additionally, shikimic acid/glyphosate ratios were used as biomarkers for glyphosate binding to its target enzyme.Four weeks after...... the exposure, glyphosate was continuously translocated. Shikimic acid levels were lin-ear correlated with glyphosate levels. After two months, however, glyphosate appeared to have reduced activity. In the greenhouse, multiple applications resulted in higher internal glyphosate concentrations.The time...

A Novel Application of Synthetic Biology and Directed Evolution to Engineer Phage-based Antibiotics

Energy Technology Data Exchange (ETDEWEB)

Wu, Meiye [Sandia National Lab. (SNL-CA), Livermore, CA (United States)

2014-09-01

The emergence of multiple drug resistant bacteria poses threats to human health, agriculture and food safety. Annually over 100,000 deaths and up to $20 billion loss to the U.S. economy are attributed to multiple drug resistant bacteria. With only four new chemical antibiotics in the drug development pipeline, we are in dire need of new solutions to address the emerging threat of multiple drug resistance. We propose a paradigm-changing approach to address the multi-drug resistant bacteria problem by utilizing Synthetic Biology (SynBio) methodologies to create and evolve “designer” bacteriophages or phages – viruses that specifically infect bacteria – to infect and kill newly emerging pathogenic bacterial strains WITHOUT the need for chemical antibiotics. A major advantage of using phage to combat pathogenic bacteria is that phages can co-evolve with their bacterial host, and Sandia can be the first in the world to establish an industrial scale Synthetic Biology pipeline for phage directed evolution for safe, targeted, customizable solution to bacterial drug resistance. Since there is no existing phage directed evolution effort within or outside of Sandia, this proposal is suitable as a high-risk LDRD effort to create the first pipeline for such an endeavor. The high potential reward nature of this proposal will be the immediate impact in decontamination and restoration of surfaces and infrastructure, with longer term impact in human or animal therapeutics. The synthetic biology and screening approaches will lead to fundamental knowledge of phage/bacteria co-evolution, making Sandia a world leader in directed evolution of bacteriophages.

75 FR 30002 - Federal Advisory Committee; Threat Reduction Advisory Committee

Science.gov (United States)

2010-05-28

... management; c. Nuclear deterrence transformation; d. Weapons effects; and e. Other Office of the Under... Reduction Agency on the following: a. Reducing the threat posed by nuclear, biological, chemical...

Threats and countermeasures for network security

Science.gov (United States)

Denning, Peter J.

1991-01-01

In the late 1980's, the traditional threat of anonymous break-ins to networked computers was joined by viruses and worms, multiplicative surrogates that carry out the bidding of their authors. Technologies for authentication and secrecy, supplemented by good management practices, are the principal countermeasures. Four articles on these subjects are presented.

Brillouin Spectroscopy Data Base for Biological Threats

National Research Council Canada - National Science Library

Rubel, Glenn

2003-01-01

.... Brillouin scattering from DNA, ovalbumen, the Bacillus spores globigii and thuringiensis were measured to determine the feasibility of biological material discrimination using Brillouin scattering...

National Strategy for Countering Biological Threats: Diplomacy and International Programs

Science.gov (United States)

2010-03-18

Regulations provide a framework for im- proving disease surveillance and reporting worldwide. In this regard, I continue to be concerned that Indonesia is not...State’s Biosecurity Engagement Program ( BEP ) is working to reduce the threat of bioterrorism through coop- erative activities to prevent terrorist...public and animal health worldwide. Since 2006, the BEP program has matured into a $37-million-a- year effort, focused on regions and countries where

Animal Botulism Outcomes in the AniBioThreat Project

DEFF Research Database (Denmark)

Woudstra, Cédric; Tevell Åberg, Annica; Skarin, Hanna

2013-01-01

and botulinum neurotoxins are considered potential weapons for bioterrorism and have been included in the Australia Group List of Biological Agents. In 2010 the European Commission (DG Justice, Freedom and Security) funded a 3-year project named AniBioThreat to improve the EU's capacity to counter animal...... new genetic information to better understand the diversity of these Clostridia and develop detection methods targeting both highly specific genetic markers of these Clostridia and the neurotoxins they are able to produce. Several European institutes participating in the AniBioThreat project...

Categorizing threat : building and using a generic threat matrix.

Energy Technology Data Exchange (ETDEWEB)

Woodard, Laura; Veitch, Cynthia K.; Thomas, Sherry Reede; Duggan, David Patrick

2007-09-01

The key piece of knowledge necessary for building defenses capable of withstanding or surviving cyber and kinetic attacks is an understanding of the capabilities posed by threats to a government, function, or system. With the number of threats continuing to increase, it is no longer feasible to enumerate the capabilities of all known threats and then build defenses based on those threats that are considered, at the time, to be the most relevant. Exacerbating the problem for critical infrastructure entities is the fact that the majority of detailed threat information for higher-level threats is held in classified status and is not available for general use, such as the design of defenses and the development of mitigation strategies. To reduce the complexity of analyzing threat, the threat space must first be reduced. This is achieved by taking the continuous nature of the threat space and creating an abstraction that allows the entire space to be grouped, based on measurable attributes, into a small number of distinctly different levels. The work documented in this report is an effort to create such an abstraction.

A Quantitative Threats Analysis for the Florida Manatee (Trichechus manatus latirostris)

Science.gov (United States)

Runge, Michael C.; Sanders-Reed, Carol A.; Langtimm, Catherine A.; Fonnesbeck, Christopher J.

2007-01-01

The Florida manatee (Trichechus manatus latirostris) is an endangered marine mammal endemic to the southeastern United States. The primary threats to manatee populations are collisions with watercraft and the potential loss of warm-water refuges. For the purposes of listing, recovery, and regulation under the Endangered Species Act (ESA), an understanding of the relative effects of the principal threats is needed. This work is a quantitative approach to threats analysis, grounded in the assumption that an appropriate measure of status under the ESA is based on the risk of extinction, as quantified by the probability of quasi-extinction. This is related to the qualitative threats analyses that are more common under the ESA, but provides an additional level of rigor, objectivity, and integration. In this approach, our philosophy is that analysis of the five threat factors described in Section 4(a)(1) of the ESA can be undertaken within an integrated quantitative framework. The basis of this threats analysis is a comparative population viability analysis. This involves forecasting the Florida manatee population under different scenarios regarding the presence of threats, while accounting for process variation (environmental, demographic, and catastrophic stochasticity) as well as parametric and structural uncertainty. We used the manatee core biological model (CBM) for this viability analysis, and considered the role of five threats: watercraft-related mortality, loss of warm-water habitat in winter, mortality in water-control structures, entanglement, and red tide. All scenarios were run with an underlying parallel structure that allowed a more powerful estimation of the effects of the various threats. The results reflect our understanding of manatee ecology (as captured in the structure of the CBM), our estimates of manatee demography (as described by the parameters in the model), and our characterization of the mechanisms by which the threats act on manatees. As an

Filling in biodiversity threat gaps

DEFF Research Database (Denmark)

Joppa, L. N.; O'Connor, Brian; Visconti, Piero

2016-01-01

increase to 10,000 times the background rate should species threatened with extinction succumb to pressures they face (4). Reversing these trends is a focus of the Convention on Biological Diversity's 2020 Strategic Plan for Biodiversity and its 20 Aichi Targets and is explicitly incorporated...... into the United Nations' 2030 Agenda for Sustainable Development and its 17 Sustainable Development Goals (SDGs). We identify major gaps in data available for assessing global biodiversity threats and suggest mechanisms for closing them....

Multiple Threats to Child Health from Fossil Fuel Combustion: Impacts of Air Pollution and Climate Change.

Science.gov (United States)

Perera, Frederica P

2017-02-01

Approaches to estimating and addressing the risk to children from fossil fuel combustion have been fragmented, tending to focus either on the toxic air emissions or on climate change. Yet developing children, and especially poor children, now bear a disproportionate burden of disease from both environmental pollution and climate change due to fossil fuel combustion. This commentary summarizes the robust scientific evidence regarding the multiple current and projected health impacts of fossil fuel combustion on the young to make the case for a holistic, child-centered energy and climate policy that addresses the full array of physical and psychosocial stressors resulting from fossil fuel pollution. The data summarized here show that by sharply reducing our dependence on fossil fuels we would achieve highly significant health and economic benefits for our children and their future. These benefits would occur immediately and also play out over the life course and potentially across generations. Going beyond the powerful scientific and economic arguments for urgent action to reduce the burning of fossil fuels is the strong moral imperative to protect our most vulnerable populations. Citation: Perera FP. 2017. Multiple threats to child health from fossil fuel combustion: impacts of air pollution and climate change. Environ Health Perspect 125:141-148; http://dx.doi.org/10.1289/EHP299.

Pervasive competition between threat and reward in the brain.

Science.gov (United States)

Choi, Jong Moon; Padmala, Srikanth; Spechler, Philip; Pessoa, Luiz

2014-06-01

In the current functional MRI study, we investigated interactions between reward and threat processing. Visual cues at the start of each trial informed participants about the chance of winning monetary reward and/or receiving a mild aversive shock. We tested two competing hypothesis: according to the 'salience hypothesis', in the condition involving both reward and threat, enhanced activation would be observed because of increased salience; according to the 'competition hypothesis', the processing of reward and threat would trade-off against each other, leading to reduced activation. Analysis of skin conductance data during a delay phase revealed an interaction between reward and threat processing, such that the effect of reward was reduced during threat and the effect of threat was reduced during reward. Analysis of imaging data during the same task phase revealed interactions between reward and threat processing in several regions, including the midbrain/ventral tegmental area, caudate, putamen, bed nucleus of the stria terminalis, anterior insula, middle frontal gyrus and dorsal anterior cingulate cortex. Taken together, our findings reveal conditions during which reward and threat trade-off against each other across multiple sites. Such interactions are suggestive of competitive processes and may reflect the organization of opponent systems in the brain. © The Author (2013). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

Heterogeneous Defensive Naval Weapon Assignment To Swarming Threats In Real Time

Science.gov (United States)

2016-03-01

come under fire from multiple sources simultaneously. These threats would be engaged in a numbers game , seeking to saturate the battlespace with many...optimization extension that uses the Python modeling language. B. TEST SCENARIO The following test scenario was developed to validate the models...Adaptive rapid response to swarming threats Concept Briefing. Presented at Naval Postgraduate School, Monterey, CA. Python [Computer Software]. (2015

Dynamics of attentional bias to threat in anxious adults: bias towards and/or away?

Science.gov (United States)

Zvielli, Ariel; Bernstein, Amit; Koster, Ernst H W

2014-01-01

The aim of the present study was to question untested assumptions about the nature of the expression of Attentional Bias (AB) towards and away from threat stimuli. We tested the idea that high trait anxious individuals (N = 106; M(SD)age = 23.9(3.2) years; 68% women) show a stable AB towards multiple categories of threatening information using the emotional visual dot probe task. AB with respect to five categories of threat stimuli (i.e., angry faces, attacking dogs, attacking snakes, pointed weapons, violent scenes) was evaluated. In contrast with current theories, we found that 34% of participants expressed AB towards threat stimuli, 20.8% AB away from threat stimuli, and 34% AB towards some categories of threat stimuli and away from others. The multiple observed expressions of AB were not an artifact of a specific criterion AB score cut-off; not specific to certain categories of threat stimuli; not an artifact of differences in within-subject variability in reaction time; nor accounted for by individual differences in anxiety-related variables. Findings are conceptualized as reflecting the understudied dynamics of AB expression, with implications for AB measurement and quantification, etiology, relations, and intervention research.

Population size, breeding biology and on-land threats of Cape Verde petrel (Pterodroma feae) in Fogo Island, Cape Verde.

Science.gov (United States)

Militão, Teresa; Dinis, Herculano Andrade; Zango, Laura; Calabuig, Pascual; Stefan, Laura M; González-Solís, Jacob

2017-01-01

Cape Verde petrel (Pterodroma feae) is currently considered near threatened, but little is known about its population size, breeding biology and on land threats, jeopardizing its management and conservation. To improve this situation, we captured, marked and recaptured (CMR) birds using mist-nets over 10 years; measured and sexed them; monitored up to 14 burrows, deployed GPS devices on breeders and analyzed activity data of geolocators retrieved from breeders in Fogo (Cape Verde). We set cat traps over the colony and investigated their domestic/feral origin by marking domestic cats from a nearby village with transponders, by deploying GPS devices on domestic cats and by performing stable isotope analyses of fur of the trapped and domestic cats. The population of Fogo was estimated to be 293 birds, including immatures (95% CI: 233-254, CMR modelling). Based on geolocator activity data and nest monitoring we determined the breeding phenology of this species and we found biometric differences between sexes. While monitoring breeding performance, we verified a still ongoing cat predation and human harvesting. Overall, data gathered from trapped cats without transponder, cats GPS trips and the distinct isotopic values between domestic and trapped cats suggest cats visiting the colony are of feral origin. GPS tracks from breeders showed birds left and returned to the colony using the sector NE of the islands, where high level of public lights should be avoided specially during the fledging period. Main threats for the Cape Verde petrel in the remaining breeding islands are currently unknown but likely to be similar to Fogo, calling for an urgent assessment of population trends and the control of main threats in all Cape Verde Islands and uplisting its conservation status.

Population size, breeding biology and on-land threats of Cape Verde petrel (Pterodroma feae in Fogo Island, Cape Verde.

Directory of Open Access Journals (Sweden)

Teresa Militão

Full Text Available Cape Verde petrel (Pterodroma feae is currently considered near threatened, but little is known about its population size, breeding biology and on land threats, jeopardizing its management and conservation. To improve this situation, we captured, marked and recaptured (CMR birds using mist-nets over 10 years; measured and sexed them; monitored up to 14 burrows, deployed GPS devices on breeders and analyzed activity data of geolocators retrieved from breeders in Fogo (Cape Verde. We set cat traps over the colony and investigated their domestic/feral origin by marking domestic cats from a nearby village with transponders, by deploying GPS devices on domestic cats and by performing stable isotope analyses of fur of the trapped and domestic cats. The population of Fogo was estimated to be 293 birds, including immatures (95% CI: 233-254, CMR modelling. Based on geolocator activity data and nest monitoring we determined the breeding phenology of this species and we found biometric differences between sexes. While monitoring breeding performance, we verified a still ongoing cat predation and human harvesting. Overall, data gathered from trapped cats without transponder, cats GPS trips and the distinct isotopic values between domestic and trapped cats suggest cats visiting the colony are of feral origin. GPS tracks from breeders showed birds left and returned to the colony using the sector NE of the islands, where high level of public lights should be avoided specially during the fledging period. Main threats for the Cape Verde petrel in the remaining breeding islands are currently unknown but likely to be similar to Fogo, calling for an urgent assessment of population trends and the control of main threats in all Cape Verde Islands and uplisting its conservation status.

[Biological research and security institutes].

Science.gov (United States)

Darsie, G; Falczuk, A J; Bergmann, I E

2006-04-01

The threat of using biological material for ago-bioterrorist ends has risen in recent years, which means that research and diagnostic laboratories, biological agent banks and other institutions authorised to carry out scientific activities have had to implement biosafety and biosecurity measures to counter the threat, while carrying out activities to help prevent and monitor the accidental or intentional introduction of exotic animal diseases. This article briefly sets outthe basic components of biosafety and biosecurity, as well as recommendations on organisational strategies to consider in laboratories that support agro-bioterrorist surveillance and prevention programs.

Cyber threat metrics.

Energy Technology Data Exchange (ETDEWEB)

Frye, Jason Neal; Veitch, Cynthia K.; Mateski, Mark Elliot; Michalski, John T.; Harris, James Mark; Trevino, Cassandra M.; Maruoka, Scott

2012-03-01

Threats are generally much easier to list than to describe, and much easier to describe than to measure. As a result, many organizations list threats. Fewer describe them in useful terms, and still fewer measure them in meaningful ways. This is particularly true in the dynamic and nebulous domain of cyber threats - a domain that tends to resist easy measurement and, in some cases, appears to defy any measurement. We believe the problem is tractable. In this report we describe threat metrics and models for characterizing threats consistently and unambiguously. The purpose of this report is to support the Operational Threat Assessment (OTA) phase of risk and vulnerability assessment. To this end, we focus on the task of characterizing cyber threats using consistent threat metrics and models. In particular, we address threat metrics and models for describing malicious cyber threats to US FCEB agencies and systems.

Enduring somatic threat perceptions and post-traumatic stress disorder symptoms in survivors of cardiac events.

Science.gov (United States)

Meli, Laura; Alcántara, Carmela; Sumner, Jennifer A; Swan, Brendan; Chang, Bernard P; Edmondson, Donald

2017-04-01

Post-traumatic stress disorder due to acute cardiovascular events may be uniquely defined by enduring perceptions of somatic threat. We tested whether post-traumatic stress disorder at 1 month post-acute coronary syndrome indeed required both high peritraumatic threat during the acute coronary syndrome and ongoing cardiac threat perceptions. We assessed peritraumatic threat during emergency department enrollment of 284 patients with a provisional acute coronary syndrome diagnosis and cardiac threat perceptions and post-traumatic stress disorder symptoms 1 month post-discharge. In a multiple regression model with adjustment for important covariates, emergency department threat perceptions were associated with higher 1 month post-traumatic stress disorder symptoms only among those with high levels of ongoing cardiac threat.

Weapons of mass destruction - current security threat

International Nuclear Information System (INIS)

Durdiak, J.; Gafrik, A.; Pulis, P.; Susko, M.

2005-01-01

This publication brings a complex and comprehensive view of the weapons of mass destruction phenomenon in the context of present military and political situation. It emphasizes the threat posed by proliferation of these destructive devices and their carriers as well as the threat present in their possession by unpredictable totalitarian regimes or terrorist groups. The publication is structured into four basic parts: Introduction Into The Topic, Nuclear Weapons, Chemical Weapons and Biological Weapons. The Introduction reflects the latest developments on the field of military technologies, which lead to the development of new destructive devices with characteristics comparable to basic types of WMDs - nuclear, chemical and biological. Based on the definition of WMD as 'weapon systems with enormous impact causing mass destruction, population, equipment and material losses', the modern mass destruction devices are assorted here, such as ecological, radiological and beam weapons, aerosol and container intelligent ammunition, the outburst of dangerous chemical substances from infrastructure, non-conventional weapons and military devices. The Nuclear Weapons part depicts the most destructive device of mass destruction mankind ever invented in close detail. It maps the history of most significant discoveries in nuclear physics, development and construction of the first nuclear weapons, accumulation of nuclear warheads and their carriers in the Cold war era, attempts of nuclear disarmament and reducing the number of nuclear weapons in possession of superpowers and their proliferation in the world's crisis regions including North Korea and Iran. The chapters devoted to theoretical grounds and physical principles of nuclear and thermonuclear weapons' functioning, the main categories and types, as well as destructive effects and consequences of use contain an adequate mathematical apparatus. This chapter's conclusion brings the overview of nuclear armament of states that

Multiple Threats to Child Health from Fossil Fuel Combustion: Impacts of Air Pollution and Climate Change

Science.gov (United States)

Perera, Frederica P.

2016-01-01

Background: Approaches to estimating and addressing the risk to children from fossil fuel combustion have been fragmented, tending to focus either on the toxic air emissions or on climate change. Yet developing children, and especially poor children, now bear a disproportionate burden of disease from both environmental pollution and climate change due to fossil fuel combustion. Objective: This commentary summarizes the robust scientific evidence regarding the multiple current and projected health impacts of fossil fuel combustion on the young to make the case for a holistic, child-centered energy and climate policy that addresses the full array of physical and psychosocial stressors resulting from fossil fuel pollution. Discussion: The data summarized here show that by sharply reducing our dependence on fossil fuels we would achieve highly significant health and economic benefits for our children and their future. These benefits would occur immediately and also play out over the life course and potentially across generations. Conclusion: Going beyond the powerful scientific and economic arguments for urgent action to reduce the burning of fossil fuels is the strong moral imperative to protect our most vulnerable populations. Citation: Perera FP. 2017. Multiple threats to child health from fossil fuel combustion: impacts of air pollution and climate change. Environ Health Perspect 125:141–148; http://dx.doi.org/10.1289/EHP299 PMID:27323709

History of chemical and biological warfare agents

International Nuclear Information System (INIS)

Szinicz, L.

2005-01-01

Chemical and biological warfare agents constitute a low-probability, but high-impact risk both to the military and to the civilian population. The use of hazardous materials of chemical or biological origin as weapons and for homicide has been documented since ancient times. The first use of chemicals in terms of weapons of mass destruction goes back to World War I, when on April 22, 1915 large amounts of chlorine were released by German military forces at Ypres, Belgium. Until around the 1970s of the 20th century, the awareness of the threat by chemical and biological agents had been mainly confined to the military sector. In the following time, the development of increasing range delivery systems by chemical and biological agents possessors sensitised public attention to the threat emanating from these agents. Their proliferation to the terrorists field during the 1990s with the expanding scale and globalisation of terrorist attacks suggested that these agents are becoming an increasing threat to the whole world community. The following article gives a condensed overview on the history of use and development of the more prominent chemical and biological warfare agents

History of chemical and biological warfare agents.

Science.gov (United States)

Szinicz, L

2005-10-30

Chemical and biological warfare agents constitute a low-probability, but high-impact risk both to the military and to the civilian population. The use of hazardous materials of chemical or biological origin as weapons and for homicide has been documented since ancient times. The first use of chemicals in terms of weapons of mass destruction goes back to World War I, when on April 22, 1915 large amounts of chlorine were released by German military forces at Ypres, Belgium. Until around the 1970s of the 20th century, the awareness of the threat by chemical and biological agents had been mainly confined to the military sector. In the following time, the development of increasing range delivery systems by chemical and biological agents possessors sensitised public attention to the threat emanating from these agents. Their proliferation to the terrorists field during the 1990s with the expanding scale and globalisation of terrorist attacks suggested that these agents are becoming an increasing threat to the whole world community. The following article gives a condensed overview on the history of use and development of the more prominent chemical and biological warfare agents.

Patterns and biases of climate change threats in the IUCN Red List.

Science.gov (United States)

Trull, Nicholas; Böhm, Monika; Carr, Jamie

2018-02-01

International Union for Conservation of Nature (IUCN) Red List assessments rely on published data and expert inputs, and biases can be introduced where underlying definitions and concepts are ambiguous. Consideration of climate change threat is no exception, and recently numerous approaches to assessing the threat of climate change to species have been developed. We explored IUCN Red List assessments of amphibians and birds to determine whether species listed as threatened by climate change display distinct patterns in terms of habitat occupied and additional nonclimatic threats faced. We compared IUCN Red List data with a published data set of species' biological and ecological traits believed to infer high vulnerability to climate change and determined whether distributions of climate change-threatened species on the IUCN Red List concur with those of climate change-threatened species identified with the trait-based approach and whether species possessing these traits are more likely to have climate change listed as a threat on the IUCN Red List. Species in some ecosystems (e.g., grassland, shrubland) and subject to particular threats (e.g., invasive species) were more likely to have climate change as a listed threat. Geographical patterns of climate change-threatened amphibians and birds on the IUCN Red List were incongruent with patterns of global species richness and patterns identified using trait-based approaches. Certain traits were linked to increases or decreases in the likelihood of a species being threatened by climate change. Broad temperature tolerance of a species was consistently related to an increased likelihood of climate change threat, indicating counterintuitive relationships in IUCN assessments. To improve the robustness of species assessments of the vulnerability or extinction risk associated with climate change, we suggest IUCN adopt a more cohesive approach whereby specific traits highlighted by our results are considered in Red List

Cognition and biology: perspectives from information theory.

Science.gov (United States)

Wallace, Rodrick

2014-02-01

The intimate relation between biology and cognition can be formally examined through statistical models constrained by the asymptotic limit theorems of communication theory, augmented by methods from statistical mechanics and nonequilibrium thermodynamics. Cognition, often involving submodules that act as information sources, is ubiquitous across the living state. Less metabolic free energy is consumed by permitting crosstalk between biological information sources than by isolating them, leading to evolutionary exaptations that assemble shifting, tunable cognitive arrays at multiple scales, and levels of organization to meet dynamic patterns of threat and opportunity. Cognition is thus necessary for life, but it is not sufficient: An organism represents a highly patterned outcome of path-dependent, blind, variation, selection, interaction, and chance extinction in the context of an adequate flow of free energy and an environment fit for development. Complex, interacting cognitive processes within an organism both record and instantiate those evolutionary and developmental trajectories.

Early adolescent adversity inflates threat estimation in females and promotes alcohol use initiation in both sexes.

Science.gov (United States)

Walker, Rachel A; Andreansky, Christopher; Ray, Madelyn H; McDannald, Michael A

2018-06-01

Childhood adversity is associated with exaggerated threat processing and earlier alcohol use initiation. Conclusive links remain elusive, as childhood adversity typically co-occurs with detrimental socioeconomic factors, and its impact is likely moderated by biological sex. To unravel the complex relationships among childhood adversity, sex, threat estimation, and alcohol use initiation, we exposed female and male Long-Evans rats to early adolescent adversity (EAA). In adulthood, >50 days following the last adverse experience, threat estimation was assessed using a novel fear discrimination procedure in which cues predict a unique probability of footshock: danger (p = 1.00), uncertainty (p = .25), and safety (p = .00). Alcohol use initiation was assessed using voluntary access to 20% ethanol, >90 days following the last adverse experience. During development, EAA slowed body weight gain in both females and males. In adulthood, EAA selectively inflated female threat estimation, exaggerating fear to uncertainty and safety, but promoted alcohol use initiation across sexes. Meaningful relationships between threat estimation and alcohol use initiation were not observed, underscoring the independent effects of EAA. Results isolate the contribution of EAA to adult threat estimation, alcohol use initiation, and reveal moderation by biological sex. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

The role of epigenetics in the biology of multiple myeloma

DEFF Research Database (Denmark)

Dimopoulos, K; Gimsing, P; Grønbæk, K

2014-01-01

Several recent studies have highlighted the biological complexity of multiple myeloma (MM) that arises as a result of several disrupted cancer pathways. Apart from the central role of genetic abnormalities, epigenetic aberrations have also been shown to be important players in the development of MM......, and a lot of research during the past decades has focused on the ways DNA methylation, histone modifications and noncoding RNAs contribute to the pathobiology of MM. This has led to, apart from better understanding of the disease biology, the development of epigenetic drugs, such as histone deacetylase...... inhibitors that are already used in clinical trials in MM with promising results. This review will present the role of epigenetic abnormalities in MM and how these can affect specific pathways, and focus on the potential of novel 'epidrugs' as future treatment modalities for MM....

Does stereotype threat affect women in academic medicine?

Science.gov (United States)

Burgess, Diana Jill; Joseph, Anne; van Ryn, Michelle; Carnes, Molly

2012-04-01

Multiple complex factors contribute to the slow pace of women's advancement into leadership positions in academic medicine. In this article, the authors propose that stereotype threat--under which individuals who are members of a group characterized by negative stereotypes in a particular domain perform below their actual abilities in that domain when group membership is emphasized--may play an important role in the underrepresentation of women in leadership positions in academic medicine. Research to objectively assess the impact of stereotype threat for women in academic medicine is feasible and necessary to confirm this hypothesis. Still, a number of conditions present in the academic medicine community today have been shown to trigger stereotype threat in other settings, and stereotype threat fits with existing research on gender in academic medicine. In the meantime, academic health centers should implement relatively simple measures supported by experimental evidence from other settings to reduce the risk of stereotype threat, including (1) introducing the concept of stereotype threat to the academic medicine community, (2) engaging all stakeholders, male and female, to promote identity safety by enacting and making faculty aware of policies to monitor potential instances of discrimination, and training faculty to provide performance feedback that is free of gender bias, (3) counteracting the effects of sex segregation at academic health centers by increasing exposure to successful female leaders, (4) reducing gender stereotype priming by avoiding stereotypically male criteria for promotion, grants, and awards, and (5) building leadership efficacy among female physicians and scientists.

Biological warfare agents

Directory of Open Access Journals (Sweden)

Duraipandian Thavaselvam

2010-01-01

Full Text Available The recent bioterrorist attacks using anthrax spores have emphasized the need to detect and decontaminate critical facilities in the shortest possible time. There has been a remarkable progress in the detection, protection and decontamination of biological warfare agents as many instrumentation platforms and detection methodologies are developed and commissioned. Even then the threat of biological warfare agents and their use in bioterrorist attacks still remain a leading cause of global concern. Furthermore in the past decade there have been threats due to the emerging new diseases and also the re-emergence of old diseases and development of antimicrobial resistance and spread to new geographical regions. The preparedness against these agents need complete knowledge about the disease, better research and training facilities, diagnostic facilities and improved public health system. This review on the biological warfare agents will provide information on the biological warfare agents, their mode of transmission and spread and also the detection systems available to detect them. In addition the current information on the availability of commercially available and developing technologies against biological warfare agents has also been discussed. The risk that arise due to the use of these agents in warfare or bioterrorism related scenario can be mitigated with the availability of improved detection technologies.

Biological warfare agents

Science.gov (United States)

Thavaselvam, Duraipandian; Vijayaraghavan, Rajagopalan

2010-01-01

The recent bioterrorist attacks using anthrax spores have emphasized the need to detect and decontaminate critical facilities in the shortest possible time. There has been a remarkable progress in the detection, protection and decontamination of biological warfare agents as many instrumentation platforms and detection methodologies are developed and commissioned. Even then the threat of biological warfare agents and their use in bioterrorist attacks still remain a leading cause of global concern. Furthermore in the past decade there have been threats due to the emerging new diseases and also the re-emergence of old diseases and development of antimicrobial resistance and spread to new geographical regions. The preparedness against these agents need complete knowledge about the disease, better research and training facilities, diagnostic facilities and improved public health system. This review on the biological warfare agents will provide information on the biological warfare agents, their mode of transmission and spread and also the detection systems available to detect them. In addition the current information on the availability of commercially available and developing technologies against biological warfare agents has also been discussed. The risk that arise due to the use of these agents in warfare or bioterrorism related scenario can be mitigated with the availability of improved detection technologies. PMID:21829313

Stereotype Threat.

Science.gov (United States)

Spencer, Steven J; Logel, Christine; Davies, Paul G

2016-01-01

When members of a stigmatized group find themselves in a situation where negative stereotypes provide a possible framework for interpreting their behavior, the risk of being judged in light of those stereotypes can elicit a disruptive state that undermines performance and aspirations in that domain. This situational predicament, termed stereotype threat, continues to be an intensely debated and researched topic in educational, social, and organizational psychology. In this review, we explore the various sources of stereotype threat, the mechanisms underlying stereotype-threat effects (both mediators and moderators), and the consequences of this situational predicament, as well as the means through which society and stigmatized individuals can overcome the insidious effects of stereotype threat. Ultimately, we hope this review alleviates some of the confusion surrounding stereotype threat while also sparking further research and debate.

Step by Step: Biology Undergraduates' Problem-Solving Procedures during Multiple-Choice Assessment.

Science.gov (United States)

Prevost, Luanna B; Lemons, Paula P

2016-01-01

This study uses the theoretical framework of domain-specific problem solving to explore the procedures students use to solve multiple-choice problems about biology concepts. We designed several multiple-choice problems and administered them on four exams. We trained students to produce written descriptions of how they solved the problem, and this allowed us to systematically investigate their problem-solving procedures. We identified a range of procedures and organized them as domain general, domain specific, or hybrid. We also identified domain-general and domain-specific errors made by students during problem solving. We found that students use domain-general and hybrid procedures more frequently when solving lower-order problems than higher-order problems, while they use domain-specific procedures more frequently when solving higher-order problems. Additionally, the more domain-specific procedures students used, the higher the likelihood that they would answer the problem correctly, up to five procedures. However, if students used just one domain-general procedure, they were as likely to answer the problem correctly as if they had used two to five domain-general procedures. Our findings provide a categorization scheme and framework for additional research on biology problem solving and suggest several important implications for researchers and instructors. © 2016 L. B. Prevost and P. P. Lemons. CBE—Life Sciences Education © 2016 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

Benefits of integrating complementarity into priority threat management.

Science.gov (United States)

Chadés, Iadine; Nicol, Sam; van Leeuwen, Stephen; Walters, Belinda; Firn, Jennifer; Reeson, Andrew; Martin, Tara G; Carwardine, Josie

2015-04-01

Conservation decision tools based on cost-effectiveness analysis are used to assess threat management strategies for improving species persistence. These approaches rank alternative strategies by their benefit to cost ratio but may fail to identify the optimal sets of strategies to implement under limited budgets because they do not account for redundancies. We devised a multiobjective optimization approach in which the complementarity principle is applied to identify the sets of threat management strategies that protect the most species for any budget. We used our approach to prioritize threat management strategies for 53 species of conservation concern in the Pilbara, Australia. We followed a structured elicitation approach to collect information on the benefits and costs of implementing 17 different conservation strategies during a 3-day workshop with 49 stakeholders and experts in the biodiversity, conservation, and management of the Pilbara. We compared the performance of our complementarity priority threat management approach with a current cost-effectiveness ranking approach. A complementary set of 3 strategies: domestic herbivore management, fire management and research, and sanctuaries provided all species with >50% chance of persistence for $4.7 million/year over 20 years. Achieving the same result cost almost twice as much ($9.71 million/year) when strategies were selected by their cost-effectiveness ranks alone. Our results show that complementarity of management benefits has the potential to double the impact of priority threat management approaches. © 2014 Society for Conservation Biology.

Capitalization of multiple intelligence types during the biology disciplines

Directory of Open Access Journals (Sweden)

Mariana DUMITRU

2010-05-01

Full Text Available The study was conducted on a sample of children at the Lăpuş School with classes I-VIII, using the teaching/learning process of the biology disciplines. A key element in applying the theory of Multiple Intelligence in a classroom is knowing the intelligence profile of children. Differentiated teaching approach was designed based on the predominant types of intelligences. For this purpose we used various methods: questionnaire, observation of children as they are given various tasks, interview, development of projects, role play, the biographical method-personal history of child, analysis of activities' results (compositions, drawings, collages, portfolios, debates in pair-groups, and case studies. In child’s profile, (types of intelligences become qualities that we capitalize in training, designing different teaching approach depending on predominant types of intelligences. The results appeared without delay. After a school's year that we worked differently with the children, they have improved school performance and became more interested in the study of biological disciplines thus arousing their curiosity and respect towards life.

Pollution, habitat loss, fishing, and climate change as critical threats to penguins.

Science.gov (United States)

Trathan, Phil N; García-Borboroglu, Pablo; Boersma, Dee; Bost, Charles-André; Crawford, Robert J M; Crossin, Glenn T; Cuthbert, Richard J; Dann, Peter; Davis, Lloyd Spencer; De La Puente, Santiago; Ellenberg, Ursula; Lynch, Heather J; Mattern, Thomas; Pütz, Klemens; Seddon, Philip J; Trivelpiece, Wayne; Wienecke, Barbara

2015-02-01

Cumulative human impacts across the world's oceans are considerable. We therefore examined a single model taxonomic group, the penguins (Spheniscidae), to explore how marine species and communities might be at risk of decline or extinction in the southern hemisphere. We sought to determine the most important threats to penguins and to suggest means to mitigate these threats. Our review has relevance to other taxonomic groups in the southern hemisphere and in northern latitudes, where human impacts are greater. Our review was based on an expert assessment and literature review of all 18 penguin species; 49 scientists contributed to the process. For each penguin species, we considered their range and distribution, population trends, and main anthropogenic threats over the past approximately 250 years. These threats were harvesting adults for oil, skin, and feathers and as bait for crab and rock lobster fisheries; harvesting of eggs; terrestrial habitat degradation; marine pollution; fisheries bycatch and resource competition; environmental variability and climate change; and toxic algal poisoning and disease. Habitat loss, pollution, and fishing, all factors humans can readily mitigate, remain the primary threats for penguin species. Their future resilience to further climate change impacts will almost certainly depend on addressing current threats to existing habitat degradation on land and at sea. We suggest protection of breeding habitat, linked to the designation of appropriately scaled marine reserves, including in the High Seas, will be critical for the future conservation of penguins. However, large-scale conservation zones are not always practical or politically feasible and other ecosystem-based management methods that include spatial zoning, bycatch mitigation, and robust harvest control must be developed to maintain marine biodiversity and ensure that ecosystem functioning is maintained across a variety of scales. © 2014 The Authors. Conservation Biology

Challenges to Leadership: Responding to Biological Threats

Science.gov (United States)

2011-10-01

45 Chemical and Biological Defense: Management Actions Are Needed to Close the Gap between...any other aspect of this collection of information, including suggestions for reducing this burden, to Washington Headquarters Services, Directorate for...contributions to it. Thanks also to Nicholas Rueter, a J.D./M.A. candidate at Duke University, for his able research assistance and to the Center for

Stereotype threat and executive functions: which functions mediate different threat-related outcomes?

Science.gov (United States)

Rydell, Robert J; Van Loo, Katie J; Boucher, Kathryn L

2014-03-01

Stereotype threat research shows that women's math performance can be reduced by activating gender-based math stereotypes. Models of stereotype threat assert that threat reduces cognitive functioning, thereby accounting for its negative effects. This work provides a more detailed understanding of the cognitive processes through which stereotype threat leads women to underperform at math and to take risks, by examining which basic executive functions (inhibition, shifting, and updating) account for these outcomes. In Experiments 1 and 2, women under threat showed reduced inhibition, reduced updating, and reduced math performance compared with women in a control condition (or men); however, only updating accounted for women's poor math performance under threat. In Experiment 3, only updating accounted for stereotype threat's effect on women's math performance, whereas only inhibition accounted for the effect of threat on risk-taking, suggesting that distinct executive functions can account for different stereotype threat-related outcomes.

Does Stereotype Threat Affect Women in Academic Medicine?

Science.gov (United States)

Burgess, Diana Jill; Joseph, Anne; van Ryn, Michelle; Carnes, Molly

2012-01-01

Multiple complex factors contribute to the slow pace of women’s advancement into leadership positions in academic medicine. In this article, the authors propose that stereotype threat--under which individuals who are members of a group characterized by negative stereotypes in a particular domain perform below their actual abilities in that domain when group membership is emphasized--may play an important role in the underrepresentation of women in leadership positions in academic medicine. Research to objectively assess the impact of stereotype threat for women in academic medicine is feasible and necessary to confirm this hypothesis. Still, a number of conditions present in the academic medicine community today have been shown to trigger stereotype threat in other settings, and stereotype threat fits with existing research on gender in academic medicine. In the meantime, academic health centers should implement relatively simple measures supported by experimental evidence from other settings to reduce the risk of stereotype threat, including: (1) introducing the concept of stereotype threat to the academic medicine community; (2) engaging all stakeholders, male and female, to promote identity safety by enacting and making faculty aware of policies to monitor potential instances of discrimination, and training faculty to provide performance feedback that is free of gender bias; (3) counteracting the effects of sex segregation at academic health centers by increasing exposure to successful female leaders; (4) reducing gender stereotype priming by avoiding stereotypically male criteria for promotion, grants, and awards; and (5) building leadership efficacy among female physicians and scientists. PMID:22361794

The Tipping Point: Biological Terrorism

Directory of Open Access Journals (Sweden)

Scott Cary

2009-01-01

Full Text Available This article presents a strategic, operational, and tactical analysis of information currently available on the state of bio-weapons development by non-state actors, primarily Islamist jihadists. It discusses the evidence supporting a practical assessment that non-state actors have begun to acquire, and in the near-term intend to employ, bio-weapons. A pathogen and method of attack specifically designed to achieve the strategic goals of jihadists are presented as functional examples of the problem of the emerging global bio-weapons threat.Is a terrorist attack utilizing biological weapons a real threat? If so, is there a way to predict the circumstances under which it might happen or how it might be conducted? This article explores what is known and cannot be known about these questions, and will examine the threat of biological terrorism in the context of the strategic goals, operational methods, and tactical intentions of Islamist terrorists.

Threat evaluation for impact assessment in situation analysis systems

Science.gov (United States)

Roy, Jean; Paradis, Stephane; Allouche, Mohamad

2002-07-01

Situation analysis is defined as a process, the examination of a situation, its elements, and their relations, to provide and maintain a product, i.e., a state of situation awareness, for the decision maker. Data fusion is a key enabler to meeting the demanding requirements of military situation analysis support systems. According to the data fusion model maintained by the Joint Directors of Laboratories' Data Fusion Group, impact assessment estimates the effects on situations of planned or estimated/predicted actions by the participants, including interactions between action plans of multiple players. In this framework, the appraisal of actual or potential threats is a necessary capability for impact assessment. This paper reviews and discusses in details the fundamental concepts of threat analysis. In particular, threat analysis generally attempts to compute some threat value, for the individual tracks, that estimates the degree of severity with which engagement events will potentially occur. Presenting relevant tracks to the decision maker in some threat list, sorted from the most threatening to the least, is clearly in-line with the cognitive demands associated with threat evaluation. A key parameter in many threat value evaluation techniques is the Closest Point of Approach (CPA). Along this line of thought, threatening tracks are often prioritized based upon which ones will reach their CPA first. Hence, the Time-to-CPA (TCPA), i.e., the time it will take for a track to reach its CPA, is also a key factor. Unfortunately, a typical assumption for the computation of the CPA/TCPA parameters is that the track velocity will remain constant. When a track is maneuvering, the CPA/TCPA values will change accordingly. These changes will in turn impact the threat value computations and, ultimately, the resulting threat list. This is clearly undesirable from a command decision-making perspective. In this regard, the paper briefly discusses threat value stabilization

Biomaterials for mediation of chemical and biological warfare agents.

Science.gov (United States)

Russell, Alan J; Berberich, Jason A; Drevon, Geraldine F; Koepsel, Richard R

2003-01-01

Recent events have emphasized the threat from chemical and biological warfare agents. Within the efforts to counter this threat, the biocatalytic destruction and sensing of chemical and biological weapons has become an important area of focus. The specificity and high catalytic rates of biological catalysts make them appropriate for decommissioning nerve agent stockpiles, counteracting nerve agent attacks, and remediation of organophosphate spills. A number of materials have been prepared containing enzymes for the destruction of and protection against organophosphate nerve agents and biological warfare agents. This review discusses the major chemical and biological warfare agents, decontamination methods, and biomaterials that have potential for the preparation of decontamination wipes, gas filters, column packings, protective wear, and self-decontaminating paints and coatings.

N deposition as a threat to the World's protected areas under the Convention on Biological Diversity

International Nuclear Information System (INIS)

Bleeker, A.; Hicks, W.K.; Dentener, F.; Galloway, J.; Erisman, J.W.

2011-01-01

This paper combines the world's protected areas (PAs) under the Convention on Biological Diversity (CBD), common classification systems of ecosystem conservation status, and current knowledge on ecosystem responses to nitrogen (N) deposition to determine areas most at risk. The results show that 40% (approx. 11% of total area) of PAs currently receive >10 kg N/ha/yr with projections for 2030 indicating that this situation is not expected to change. Furthermore, 950 PAs are projected to receive >30 kg N/ha/yr by 2030 (approx. twice the 2000 number), of which 62 (approx. 11,300 km 2 ) are also Biodiversity Hotspots and G200 ecoregions; with forest and grassland ecosystems in Asia particularly at risk. Many of these sites are known to be sensitive to N deposition effects, both in terms of biodiversity changes and ecosystem services they provide. Urgent assessment of high risk areas identified in this study is recommended to inform the conservation efforts of the CBD. - Highlights: → Significant areas of the Protected Areas Programme under the CBD will likely be under threat of high N deposition levels by the year 2030.→ Approx. 950 PAs are projected to receive N deposition levels of more than 30 kg N/ha/yr by 2030.→ 62 of these sites are also Biodiversity Hotspots and G200 ecoregions, where forest and grassland ecosystems in Asia will be particularly at risk.→ Many of these sites are known to be sensitive to N deposition effects, both in terms of biodiversity changes and ecosystem services they provide → Urgent assessment of high risk areas identified in this study is recommended to inform the conservation efforts of the CBD. - Significant areas of the UNEP Protected Areas Programme under the CBD receive high N deposition rates that are likely to increase in the future, especially in Asia, and may pose a significant threat to biodiversity.

Chemical and biological warfare. Should defenses be researched and deployed?

Science.gov (United States)

Orient, J M

1989-08-04

The threat of chemical and biological weapons of mass destruction has intensified because of improved delivery systems and advances in chemistry, genetics, and other sciences. Possible US responses to this threat include deterrence, defenses, and/or disarmament, including a reaffirmation of the Biological and Toxin Weapons Convention of 1972, which is now in jeopardy. This article discusses the history of chemical and biological warfare, existing and potential weapons, the proliferation of weapons and delivery systems, ways to prevent the use of these weapons, and ways to protect populations from their effects.

Improving Visual Threat Detection: Research to Validate the Threat Detection Skills Trainer

Science.gov (United States)

2013-08-01

26 Threat Detection and Mitigation Strategies...quicker when identifying threats in relevant locations. This task utilized the Flicker paradigm (Rensink, O’Regan, & Clark, 1997; Scholl, 2000...the meaning and implication of threats, why cues were relevant, strategies used to detect and mitigate threats, and challenges when attempting to

Law Enforcement Use of Threat Assessments to Predict Violence

Science.gov (United States)

Wood, Tracey Michelle

2016-01-01

The purpose of this qualitative, descriptive multiple case study was to explore what process, policies and procedures, or set of empirically supported norms governed law enforcement officers in a selected county in the southwest region of the United States when threat assessments were conducted on potentially violent subjects threatening mass…

Experimental strategies to assess the biological ramifications of multiple drivers of global ocean change-A review.

Science.gov (United States)

Boyd, Philip W; Collins, Sinead; Dupont, Sam; Fabricius, Katharina; Gattuso, Jean-Pierre; Havenhand, Jonathan; Hutchins, David A; Riebesell, Ulf; Rintoul, Max S; Vichi, Marcello; Biswas, Haimanti; Ciotti, Aurea; Gao, Kunshan; Gehlen, Marion; Hurd, Catriona L; Kurihara, Haruko; McGraw, Christina M; Navarro, Jorge M; Nilsson, Göran E; Passow, Uta; Pörtner, Hans-Otto

2018-06-01

Marine life is controlled by multiple physical and chemical drivers and by diverse ecological processes. Many of these oceanic properties are being altered by climate change and other anthropogenic pressures. Hence, identifying the influences of multifaceted ocean change, from local to global scales, is a complex task. To guide policy-making and make projections of the future of the marine biosphere, it is essential to understand biological responses at physiological, evolutionary and ecological levels. Here, we contrast and compare different approaches to multiple driver experiments that aim to elucidate biological responses to a complex matrix of ocean global change. We present the benefits and the challenges of each approach with a focus on marine research, and guidelines to navigate through these different categories to help identify strategies that might best address research questions in fundamental physiology, experimental evolutionary biology and community ecology. Our review reveals that the field of multiple driver research is being pulled in complementary directions: the need for reductionist approaches to obtain process-oriented, mechanistic understanding and a requirement to quantify responses to projected future scenarios of ocean change. We conclude the review with recommendations on how best to align different experimental approaches to contribute fundamental information needed for science-based policy formulation. © 2018 John Wiley & Sons Ltd.

Predictive Validity of Explicit and Implicit Threat Overestimation in Contamination Fear

Science.gov (United States)

Green, Jennifer S.; Teachman, Bethany A.

2012-01-01

We examined the predictive validity of explicit and implicit measures of threat overestimation in relation to contamination-fear outcomes using structural equation modeling. Undergraduate students high in contamination fear (N = 56) completed explicit measures of contamination threat likelihood and severity, as well as looming vulnerability cognitions, in addition to an implicit measure of danger associations with potential contaminants. Participants also completed measures of contamination-fear symptoms, as well as subjective distress and avoidance during a behavioral avoidance task, and state looming vulnerability cognitions during an exposure task. The latent explicit (but not implicit) threat overestimation variable was a significant and unique predictor of contamination fear symptoms and self-reported affective and cognitive facets of contamination fear. On the contrary, the implicit (but not explicit) latent measure predicted behavioral avoidance (at the level of a trend). Results are discussed in terms of differential predictive validity of implicit versus explicit markers of threat processing and multiple fear response systems. PMID:24073390

Sensors Provide Early Warning of Biological Threats

Science.gov (United States)

2009-01-01

Early Warning Inc. of Troy, New York, licensed powerful biosensor technology from Ames Research Center. Incorporating carbon nanotubes tipped with single strands of nucleic acid from waterborne pathogens, the sensor can detect even minute amounts of targeted, disease causing bacteria, viruses, and parasites. Early Warning features the NASA biosensor in its water analyzer, which can provide advance alert of potential biological hazards in water used for agriculture, food and beverages, showers, and at beaches and lakes -- within hours instead of the days required by conventional laboratory methods.

Scaling range sizes to threats for robust predictions of risks to biodiversity.

Science.gov (United States)

Keith, David A; Akçakaya, H Resit; Murray, Nicholas J

2018-04-01

Assessments of risk to biodiversity often rely on spatial distributions of species and ecosystems. Range-size metrics used extensively in these assessments, such as area of occupancy (AOO), are sensitive to measurement scale, prompting proposals to measure them at finer scales or at different scales based on the shape of the distribution or ecological characteristics of the biota. Despite its dominant role in red-list assessments for decades, appropriate spatial scales of AOO for predicting risks of species' extinction or ecosystem collapse remain untested and contentious. There are no quantitative evaluations of the scale-sensitivity of AOO as a predictor of risks, the relationship between optimal AOO scale and threat scale, or the effect of grid uncertainty. We used stochastic simulation models to explore risks to ecosystems and species with clustered, dispersed, and linear distribution patterns subject to regimes of threat events with different frequency and spatial extent. Area of occupancy was an accurate predictor of risk (0.81<|r|<0.98) and performed optimally when measured with grid cells 0.1-1.0 times the largest plausible area threatened by an event. Contrary to previous assertions, estimates of AOO at these relatively coarse scales were better predictors of risk than finer-scale estimates of AOO (e.g., when measurement cells are <1% of the area of the largest threat). The optimal scale depended on the spatial scales of threats more than the shape or size of biotic distributions. Although we found appreciable potential for grid-measurement errors, current IUCN guidelines for estimating AOO neutralize geometric uncertainty and incorporate effective scaling procedures for assessing risks posed by landscape-scale threats to species and ecosystems. © 2017 The Authors. Conservation Biology published by Wiley Periodicals, Inc. on behalf of Society for Conservation Biology.

Biophysics and the Challenges of Emerging Threats

CERN Document Server

Puglisi, Joseph D

2009-01-01

This volume is a collection of articles from the proceedings of the International School of Structural Biology and Magnetic Resonance 8th Course: Biophysics and the Challenges of Emerging Threats. This NATO Advance Study Institute (ASI) was held in Erice at the Ettore Majorana Foundation and Centre for Scientific Culture on 19 through 30 June 2007. The ASI brought together a diverse group of experts who bridged the fields of virology and biology, biophysics, chemistry and physics. Prominent lecturers and students from around the world representant a total of 24 countries participated in the NATO ASI organized by Professors Joseph Puglisi (Stanford University, USA) and Alexander Arseniev (Moscow, RU). The central hypothesis underlying this ASI was that interdisciplinary research, merging principles of physics, chemistry and biology, can drive new discovery in detecting and fighting bioterrorism agents, lead to cleaner environments, and help propel development in NATO partner countries. The ASI merged the relat...

Step by Step: Biology Undergraduates’ Problem-Solving Procedures during Multiple-Choice Assessment

Science.gov (United States)

Prevost, Luanna B.; Lemons, Paula P.

2016-01-01

This study uses the theoretical framework of domain-specific problem solving to explore the procedures students use to solve multiple-choice problems about biology concepts. We designed several multiple-choice problems and administered them on four exams. We trained students to produce written descriptions of how they solved the problem, and this allowed us to systematically investigate their problem-solving procedures. We identified a range of procedures and organized them as domain general, domain specific, or hybrid. We also identified domain-general and domain-specific errors made by students during problem solving. We found that students use domain-general and hybrid procedures more frequently when solving lower-order problems than higher-order problems, while they use domain-specific procedures more frequently when solving higher-order problems. Additionally, the more domain-specific procedures students used, the higher the likelihood that they would answer the problem correctly, up to five procedures. However, if students used just one domain-general procedure, they were as likely to answer the problem correctly as if they had used two to five domain-general procedures. Our findings provide a categorization scheme and framework for additional research on biology problem solving and suggest several important implications for researchers and instructors. PMID:27909021

Identifying and Mitigating Insider Threats

DEFF Research Database (Denmark)

Probst, Christian W.

2011-01-01

Organisations face many threats that coarsely can be separated in inside threats and outside threats. Threats from insiders are especially hard to counter since insiders have special knowledge and privileges. Therefore, malicious insider actions are hard to distinguish from benign actions. After ...... discussing new definitions of insiders and insider threats, this article gives an overview of how to mitigate insider threats and discusses conflicting goals when dealing with insider threats....

Examining perceived stereotype threat among overweight/obese adults using a multi-threat framework.

Science.gov (United States)

Carels, Robert A; Domoff, Sarah E; Burmeister, Jacob M; Koball, Afton M; Hinman, Nova G; Davis, Alan K; Wagner Oehlhof, Marissa; Leroy, Michelle; Bannon, Erin; Hoffmann, Debra A

2013-01-01

The Multi-Threat Framework accounts for potentially different forms of stereotype threat that differ in target (i.e., the individual or the group) and source (i.e., the self or others). This investigation examined how these different forms of perceived stereotype threat were related to concepts, such as group identity, stereotype endorsement, stigma consciousness, etc., among overweight and obese individuals. 216 adults completed an online survey. Participants' mean age was 23.6 (SD 10.1; range 18-64) years and mean BMI was 31.6 (SD 7.5) kg/m². Participants reported a history of feeling threatened by stereotypes related to weight. When reflecting on past experiences of perceived stereotype threat, participants reported greater levels of self/own stereotype threat compared to group stereotype threat. Level of stereotype threat was related to a number of personal characteristics (i.e., sex, BMI) and individual factors (i.e., group identity, stigma consciousness, fear of fat). Individuals who are overweight report a history of being threatened by negative stereotypes. The findings support the Multi-Threat Framework for stereotype threat based on body weight. Overweight individuals' susceptibility to stereotype threat may vary systematically depending on several factors. Future research should examine weight-related stereotypes' impact on cognitive and behavioral outcomes. Copyright © 2013 S. Karger GmbH, Freiburg

Examining Perceived Stereotype Threat among Overweight/Obese Adults Using a Multi-Threat Framework

Directory of Open Access Journals (Sweden)

Robert A. Carels

2013-05-01

Full Text Available Objective: The Multi-Threat Framework accounts for potentially different forms of stereotype threat that differ in target (i.e., the individual or the group and source (i.e., the self or others. This investigation examined how these different forms of perceived stereotype threat were related to concepts, such as group identity, stereotype endorsement, stigma consciousness, etc., among overweight and obese individuals. Method: 216 adults completed an online survey. Participants' mean age was 23.6 (SD 10.1; range 18-64 years and mean BMI was 31.6 (SD 7.5 kg/m2. Results: Participants reported a history of feeling threatened by stereotypes related to weight. When reflecting on past experiences of perceived stereotype threat, participants reported greater levels of self/own stereotype threat compared to group stereotype threat. Level of stereotype threat was related to a number of personal characteristics (i.e., sex, BMI and individual factors (i.e., group identity, stigma consciousness, fear of fat. Conclusion: Individuals who are overweight report a history of being threatened by negative stereotypes. The findings support the Multi-Threat Framework for stereotype threat based on body weight. Overweight individuals' susceptibility to stereotype threat may vary systematically depending on several factors. Future research should examine weight-related stereotypes' impact on cognitive and behavioral outcomes.

Are all interventions created equal? A multi-threat approach to tailoring stereotype threat interventions.

Science.gov (United States)

Shapiro, Jenessa R; Williams, Amy M; Hambarchyan, Mariam

2013-02-01

To date, stereotype threat interventions have been considered interchangeable. Across 4 experiments, the present research demonstrates that stereotype threat interventions need to be tailored to the specific form of experienced stereotype threat to be effective. The Multi-Threat Framework (Shapiro & Neuberg, 2007) distinguishes between group-as-target stereotype threats-concerns that a stereotype-relevant performance will reflect poorly on the abilities of one's group-and self-as-target stereotype threats-concerns that a stereotype-relevant performance will reflect poorly on one's own abilities. The present experiments explored Black college students' performance on diagnostic intelligence tests (Experiments 1 and 3) and women's interest (Experiment 2) and performance (Experiment 4) in science, technology, engineering, and math (STEM). Across the 4 experiments, participants were randomly assigned to experience either a group-as-target or self-as-target stereotype threat. Experiments 1 and 2 revealed that role model interventions were successful at protecting only against group-as-target stereotype threats, and Experiments 3 and 4 revealed that self-affirmation interventions were successful at protecting only against self-as-target stereotype threats. The present research provides an experimental test of the Multi-Threat Framework across different negatively stereotyped groups (Black students, female students), different negatively stereotyped domains (general intelligence, STEM), and different outcomes (test performance, career interest). This research suggests that interventions should address the range of possible stereotype threats to effectively protect individuals against these threats. Through an appreciation of the distinct forms of stereotype threats and the ways in which interventions work to reduce them, this research aims to facilitate a more complete understanding of stereotype threat. (c) 2013 APA, all rights reserved.

Biological technologies for the remediation of co-contaminated soil.

Science.gov (United States)

Ye, Shujing; Zeng, Guangming; Wu, Haipeng; Zhang, Chang; Dai, Juan; Liang, Jie; Yu, Jiangfang; Ren, Xiaoya; Yi, Huan; Cheng, Min; Zhang, Chen

2017-12-01

Compound contamination in soil, caused by unreasonable waste disposal, has attracted increasing attention on a global scale, particularly since multiple heavy metals and/or organic pollutants are entering natural ecosystem through human activities, causing an enormous threat. The remediation of co-contaminated soil is more complicated and difficult than that of single contamination, due to the disparate remediation pathways utilized for different types of pollutants. Several modern remediation technologies have been developed for the treatment of co-contaminated soil. Biological remediation technologies, as the eco-friendly methods, have received widespread concern due to soil improvement besides remediation. This review summarizes the application of biological technologies, which contains microbial technologies (function microbial remediation and composting or compost addition), biochar, phytoremediation technologies, genetic engineering technologies and biochemical technologies, for the remediation of co-contaminated soil with heavy metals and organic pollutants. Mechanisms of these technologies and their remediation efficiencies are also reviewed. Based on this study, this review also identifies the future research required in this field.

Authoritarianism, conservatism, racial diversity threat, and the state distribution of hate groups.

Science.gov (United States)

McCann, Stewart J H

2010-01-01

On the basis of K. Stenner's (2005) authoritarian dynamic theory, the author hypothesized that there is an interaction between U.S. state conservatism-liberalism and state racial heterogeneity threat, such that greater diversity threat tends to be associated with more hate groups in more conservative states and fewer hate groups in more liberal states. State aggregates of the conservative-liberal ideological preferences of 141,798 participants from 122 CBS News/New York Times national telephone polls conducted between 1976 and 1988 (R. S. Erikson, G. C. Wright, & J. P. McIver, 1993) served as proxies for authoritarian-nonauthoritarian dispositions. For the 47 states with complete data, the hypothesized interaction was tested for 2000, 2005, and 2006 with hierarchical multiple regression strategies and supported. The author's hypothesis was also affirmed with SES and the interaction of SES and diversity threat controlled for. In contrast, SES entirely accounted for simple relationships between threat and hate group frequency.

Assessing the impact of the U.S. Endangered Species Act recovery planning guidelines on managing threats for listed species.

Science.gov (United States)

Troyer, Caitlin M; Gerber, Leah R

2015-10-01

The Endangered Species Act (ESA) of the United States was enacted in 1973 to prevent the extinction of species. Recovery plans, required by 1988 amendments to the ESA, play an important role in organizing these efforts to protect and recover species. To improve the use of science in the recovery planning process, the Society for Conservation Biology (SCB) commissioned an independent review of endangered species recovery planning in 1999. From these findings, the SCB made key recommendations for how management agencies could improve the recovery planning process, after which the U.S. Fish and Wildlife Service and the National Marine Fisheries Service redrafted their recovery planning guidelines. One important recommendation called for recovery plans to make threats a primary focus, including organizing and prioritizing recovery tasks for threat abatement. We sought to determine the extent to which results from the SCB study were incorporated into these new guidelines and whether the SCB recommendations regarding threats manifested in recovery plans written under the new guidelines. Recovery planning guidelines generally incorporated the SCB recommendations, including those for managing threats. However, although recent recovery plans have improved in their treatment of threats, many fail to adequately incorporate threat monitoring. This failure suggests that developing clear guidelines for monitoring should be an important priority in improving ESA recovery planning. © 2015 Society for Conservation Biology.

The terrorist threat nuclear, radiological, biological, chemical - a medical approach

International Nuclear Information System (INIS)

Revel, M.C. de; Gourmelon, M.C.S.; Vidal, P.C.; Renaudeau, P.C.S.

2005-01-01

Since September 11, 2001, the fear of a large scale nuclear, biological and/or chemical terrorism is taken again into consideration at the highest level of national policies of risk prevention. The advent of international terrorism implies a cooperation between the military defense and the civil defense. The nuclear, radiological, biological and chemical (NRBC) experts of the health service of army and of civil defense will have to work together in case of major terror attack. This book presents this cooperation between civil and military experts in the NRBC domain: risk analysis, national defense plans, crisis management, syndromes and treatments. The different aspects linked with the use of nuclear, biological and chemical weapons are analyzed by the best experts from French medical and research institutes. All topics of each NRBC domain are approached: historical, basic, diagnostic, therapeutic and preventive. (J.S.)

An integrated approach to risk assessment and mitigating the CBRN threat

International Nuclear Information System (INIS)

Bokan, S.

2009-01-01

CBRN mass casualty events threat mitigation remains today the highest international priority. Although significant progress has been made, the national security requirements for efforts to combat Weapons of Mass Destruction and Weapons of Mass Disruption will be of the highest national priority in the near future. An integration of a number of approaches is essential in the risk assessment and mitigating the CBRN treat. Preparedness measures and procedures, engineering, science and technology, policy, medical, and emergency response are essential to reduce the threat from the proliferation and use of weapons of mass destruction (WMD). Improved coordination between international, public and private security entities is also essential task to hopefully prevent the terrorist attacks. In this lecture, it will be presented very important scientific approach to risk assessment of potential use of nuclear, radiological, biological or chemical weapons in terrorist actions. An integrated approach for mitigating the CBRN threat, crisis management and preparedness measures for prevention and reduction of potential consequences, will be presented.(author)

Anxiety and Threat-Related Attention: Cognitive-Motivational Framework and Treatment.

Science.gov (United States)

Mogg, Karin; Bradley, Brendan P

2018-03-01

Research in experimental psychopathology and cognitive theories of anxiety highlight threat-related attention biases (ABs) and underpin the development of a computer-delivered treatment for anxiety disorders: attention-bias modification (ABM) training. Variable effects of ABM training on anxiety and ABs generate conflicting research recommendations, novel ABM training procedures, and theoretical controversy. This article summarises an updated cognitive-motivational framework, integrating proposals from cognitive models of anxiety and attention, as well as evidence of ABs. Interactions between motivational salience-driven and goal-directed influences on multiple cognitive processes (e.g., stimulus evaluation, inhibition, switching, orienting) underlie anxiety and the variable manifestations of ABs (orienting towards and away from threat; threat-distractor interference). This theoretical analysis also considers ABM training as cognitive skill training, describes a conceptual framework for evaluating/developing novel ABM training procedures, and complements network-based research on reciprocal anxiety-cognition relationships. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

Stereotype Threat and College Academic Performance: A Latent Variables Approach*

Science.gov (United States)

Owens, Jayanti; Massey, Douglas S.

2013-01-01

Stereotype threat theory has gained experimental and survey-based support in helping explain the academic underperformance of minority students at selective colleges and universities. Stereotype threat theory states that minority students underperform because of pressures created by negative stereotypes about their racial group. Past survey-based studies, however, are characterized by methodological inefficiencies and potential biases: key theoretical constructs have only been measured using summed indicators and predicted relationships modeled using ordinary least squares. Using the National Longitudinal Survey of Freshman, this study overcomes previous methodological shortcomings by developing a latent construct model of stereotype threat. Theoretical constructs and equations are estimated simultaneously from multiple indicators, yielding a more reliable, valid, and parsimonious test of key propositions. Findings additionally support the view that social stigma can indeed have strong negative effects on the academic performance of pejoratively stereotyped racial-minority group members, not only in laboratory settings, but also in the real world. PMID:23950616

The concept of ego threat in social and personality psychology: is ego threat a viable scientific construct?

Science.gov (United States)

Leary, Mark R; Terry, Meredith L; Batts Allen, Ashley; Tate, Eleanor B

2009-08-01

Although widely invoked as an explanation for psychological phenomena, ego threat has been conceptualized and induced in a variety of ways. Most contemporary research conceptualizes ego threat as a threat to a person's self-image or self-esteem, but experimental operationalizations of ego threat usually confound threats to self-esteem with threats to public image or decreased control over negative events, leading to an inability to distinguish the effects of threats to people's personal egos from threats to public image or threats to feelings of control. This article reviews research on ego threat, discusses experimental manipulations that confound ego threat with other processes, and makes recommendations regarding the use of ego threat as a construct in personality and social psychology.

Conservation threats and the phylogenetic utility of IUCN Red List rankings in Incilius toads.

Science.gov (United States)

Schachat, Sandra R; Mulcahy, Daniel G; Mendelson, Joseph R

2016-02-01

Phylogenetic analysis of extinction threat is an emerging tool in the field of conservation. However, there are problems with the methods and data as commonly used. Phylogenetic sampling usually extends to the level of family or genus, but International Union for Conservation of Nature (IUCN) rankings are available only for individual species, and, although different species within a taxonomic group may have the same IUCN rank, the species may have been ranked as such for different reasons. Therefore, IUCN rank may not reflect evolutionary history and thus may not be appropriate for use in a phylogenetic context. To be used appropriately, threat-risk data should reflect the cause of extinction threat rather than the IUCN threat ranking. In a case study of the toad genus Incilius, with phylogenetic sampling at the species level (so that the resolution of the phylogeny matches character data from the IUCN Red List), we analyzed causes of decline and IUCN threat rankings by calculating metrics of phylogenetic signal (such as Fritz and Purvis' D). We also analyzed the extent to which cause of decline and threat ranking overlap by calculating phylogenetic correlation between these 2 types of character data. Incilius species varied greatly in both threat ranking and cause of decline; this variability would be lost at a coarser taxonomic resolution. We found far more phylogenetic signal, likely correlated with evolutionary history, for causes of decline than for IUCN threat ranking. Individual causes of decline and IUCN threat rankings were largely uncorrelated on the phylogeny. Our results demonstrate the importance of character selection and taxonomic resolution when extinction threat is analyzed in a phylogenetic context. © 2015 Society for Conservation Biology.

Does Stereotype Threat Affect Women in Academic Medicine?

OpenAIRE

Burgess, Diana Jill; Joseph, Anne; van Ryn, Michelle; Carnes, Molly

2012-01-01

Multiple complex factors contribute to the slow pace of women’s advancement into leadership positions in academic medicine. In this article, the authors propose that stereotype threat--under which individuals who are members of a group characterized by negative stereotypes in a particular domain perform below their actual abilities in that domain when group membership is emphasized--may play an important role in the underrepresentation of women in leadership positions in academic medicine. Re...

Status and threats analysis for the Florida manatee (Trichechus manatus latirostris), 2016

Science.gov (United States)

Runge, Michael C.; Sanders-Reed, Carol A.; Langtimm, Catherine A.; Hostetler, Jeffrey A.; Martin, Julien; Deutsch, Charles J.; Ward-Geiger, Leslie I.; Mahon, Gary L.

2017-04-11

Trichechus manatus (West Indian manatee), especially T. m. latirostris, the Florida subspecies, has been the focus of conservation efforts and extensive research since its listing under the Endangered Species Act of 1973. To determine the status of, and severity of threats to, the Florida manatee, a comprehensive revision and update of the manatee Core Biological Model was completed and used to perform a population viability analysis for the Florida manatee. The probability of the Florida manatee population falling below 500 adults on either the Gulf or East coast within the next 100 years was estimated to be 0.42 percent. This risk of quasi-extinction is low because the estimated adult survival rates are high, the current population size is greater than 2,500 on each coast, and the estimated carrying capacity for manatees is much larger than the current abundance estimates in all four regions of Florida. Three threats contribute in roughly equal measures to the risk of quasi-extinction: watercraft-related mortality, red-tide mortality, and loss of warm-water habitat. Only an increase in watercraft-related mortality has the potential to substantially increase the risk of quasi-extinction at the statewide or coastal level. Expected losses of warm-water habitat are likely to cause a major change in the distribution of the population from the regions where manatees rely heavily on power plant effluents for warmth in winter (Southwest and Atlantic regions) to the regions where manatees primarily use natural springs in winter (Northwest and Upper St. Johns regions). The chances are nearly 50 percent that manatee populations in the Southwest and Atlantic regions will decrease from their 2011 levels by at least 30 percent over the next century.A large number of scenarios were examined to explore the possible effects of potential emerging threats, and in most of them, the risk of quasi-extinction at the coastal scale within 100 years did not rise above 1 percent. The four

Insiders and Insider Threats

DEFF Research Database (Denmark)

Hunker, Jeffrey; Probst, Christian W.

2011-01-01

Threats from the inside of an organization’s perimeters are a significant problem, since it is difficult to distinguish them from benign activity. In this overview article we discuss defining properties of insiders and insider threats. After presenting definitions of these terms, we go on to disc......Threats from the inside of an organization’s perimeters are a significant problem, since it is difficult to distinguish them from benign activity. In this overview article we discuss defining properties of insiders and insider threats. After presenting definitions of these terms, we go...

Adaption of Ulva pertusa to multiple-contamination of heavy metals and nutrients: Biological mechanism of outbreak of Ulva sp. green tide.

Science.gov (United States)

Ge, Changzi; Yu, Xiru; Kan, Manman; Qu, Chunfeng

2017-12-15

The multiple-contamination of heavy metals and nutrients worsens increasingly and Ulva sp. green tide occurs almost simultaneously. To reveal the biological mechanism for outbreak of the green tide, Ulva pertusa was exposed to seven-day-multiple-contamination. The relation between pH variation (V pH ), Chl a content, ratio of (Chl a content)/(Chl b content) (R chla/chlb ), SOD activity of U. pertusa (A SOD ) and contamination concentration is [Formula: see text] (pcontamination concentrations of seawaters where Ulva sp. green tide occurred and the contamination concentrations set in the present work, U. pertusa can adapt to multiple-contaminations in these waters. Thus, the adaption to multiple-contamination may be one biological mechanism for the outbreak of Ulva sp. green tide. Copyright © 2017 Elsevier Ltd. All rights reserved.

Clinical and biological features of multiple myeloma involving the gastrointestinal system.

Science.gov (United States)

Talamo, Giampaolo; Cavallo, Federica; Zangari, Maurizio; Barlogie, Bart; Lee, Choon-Kee; Pineda-Roman, Mauricio; Kiwan, Elias; Krishna, Somashekar; Tricot, Guido

2006-07-01

We report 24 cases of multiple myeloma (MM) with involvement of the gastrointestinal (GI) system. We found a strong association with high A lactate dehydrogenase levels, plasmablastic morphology, and A unfavorable karyotype. GI involvement at the time of initial diagnosis was much rarer than later in the course of the disease. The A median survival after diagnosis of GI involvement was 7 months. Among 13 patients treated with stem cell transplantation, the response rate was 92%, and median progression-free survival was 4 months. We conclude that MM involving the GI system is associated with adverse biological features and with short-lasting remissions, even after A high-dose chemotherapy.

Stress appraisals and cellular aging: A key role for anticipatory threat in the relationship between psychological stress and telomere length

Science.gov (United States)

O’Donovan, Aoife; Tomiyama, A. Janet; Lin, Jue; Puterman, Eli; Adler, Nancy E.; Kemeny, Margaret; Wolkowitz, Owen M.; Blackburn, Elizabeth H.; Epel, Elissa S.

2012-01-01

Chronic psychological stressis a risk factor formultiple diseases of aging. Accelerated cellular aging as indexed by short telomere length has emerged as a potential common biological mechanism linking various forms of psychological stress and diseases of aging. Stress appraisals determine the degree and type of biological stress responses and altered stress appraisals may be a common psychological mechanism linking psychological stress and diseases of aging. However, no previous studies have examined the relationship between stress appraisals and telomere length. We exposed chronically stressed female caregivers and non-caregiving controls (N= 50; M age = 62.14±6.10) to a standardized acute laboratory stressor and measured their anticipatory and retrospective threat and challenge appraisals of the stressor. We hypothesized that threat and challenge appraisals would be associated with shorter and longer telomere length respectively, and that chronic care giving stress would influence telomere length through altered stress appraisals. Higher anticipatory threat appraisals were associated with shorter age-adjusted telomere length (β = −.32, p = .03), but challenge appraisals and retrospective threat appraisals showed no independent association with telomere length. Caregivers reported significantly higher anticipatory (β = −.36, p = .006)and retrospective (β = −.29, p = .03) threat appraisals than controls, but similar challenge appraisals. Although there was no significant main effect of caregiver status on telomere length, care giving had a significant indirect effect on telomere length through anticipatory threat appraisals. Exaggerated anticipatory threat appraisals may be a common and modifiable psychological mechanism of psychological stress effects on cellular aging. PMID:22293459

Poland and Global Threats

Science.gov (United States)

Kleer, Jerzy

2016-01-01

This essay seeks to present the specifics of global threats, as well as the reasons for them being universal in nature, and for their persistence. A certain classification of the threats is also engaged in. At the same time, an attempt is made to show the specific threats present - irrespective of their global counterparts - in different regions, and even in different states. The genesis and nature of the latter are demonstrated in a somewhat ad hoc manner by reference to the threats considered to face Poland. If the global threats are truly universal, and arise out of the changes taking place around the world in the last half-century (primarily around the twin phenomena of globalisation and the information revolution), a specific reverse kind of situation applies to decolonisation, plus the collapse of the communist system and the transformation into market economies that apply to formerly communist countries. Equally, some at least of the threats facing Poland may have even a longer history, given that they are very much influenced by past economic and political development, as well as the dominant cultural system.

International trade drives biodiversity threats in developing nations.

Science.gov (United States)

Lenzen, M; Moran, D; Kanemoto, K; Foran, B; Lobefaro, L; Geschke, A

2012-06-06

Human activities are causing Earth's sixth major extinction event-an accelerating decline of the world's stocks of biological diversity at rates 100 to 1,000 times pre-human levels. Historically, low-impact intrusion into species habitats arose from local demands for food, fuel and living space. However, in today's increasingly globalized economy, international trade chains accelerate habitat degradation far removed from the place of consumption. Although adverse effects of economic prosperity and economic inequality have been confirmed, the importance of international trade as a driver of threats to species is poorly understood. Here we show that a significant number of species are threatened as a result of international trade along complex routes, and that, in particular, consumers in developed countries cause threats to species through their demand of commodities that are ultimately produced in developing countries. We linked 25,000 Animalia species threat records from the International Union for Conservation of Nature Red List to more than 15,000 commodities produced in 187 countries and evaluated more than 5 billion supply chains in terms of their biodiversity impacts. Excluding invasive species, we found that 30% of global species threats are due to international trade. In many developed countries, the consumption of imported coffee, tea, sugar, textiles, fish and other manufactured items causes a biodiversity footprint that is larger abroad than at home. Our results emphasize the importance of examining biodiversity loss as a global systemic phenomenon, instead of looking at the degrading or polluting producers in isolation. We anticipate that our findings will facilitate better regulation, sustainable supply-chain certification and consumer product labelling.

Are All Interventions Created Equal? A Multi-Threat Approach to Tailoring Stereotype Threat Interventions

OpenAIRE

Shapiro, Jenessa R.; Williams, Amy M.; Hambarchyan, Mariam

2012-01-01

To date, stereotype threat interventions have been considered interchangeable. Across 4 experiments, the present research demonstrates that stereotype threat interventions need to be tailored to the specific form of experienced stereotype threat to be effective. The Multi-Threat Framework (Shapiro & Neuberg, 2007) distinguishes between group-as-target stereotype threats—concerns that a stereotype-relevant performance will reflect poorly on the abilities of one’s group—and self-as-target stere...

Perceived Threat of Malaria and the Use of Insecticide Treated Bed ...

African Journals Online (AJOL)

Using multiple qualitative methods, this study investigated the perceived threat and perceived susceptibility of children under five years of age to malaria, and willingness of the caregivers to use the ITNs in the prevention of malaria in selected rural and urban areas of Nigeria. The health belief model (HBM) is the theoretical ...

Terrorist threat, chemical, biological, radiological, nuclear medical approach

International Nuclear Information System (INIS)

Revel, Th. de; Gourmelon, P.; Vidal, D.; Renaudeau, C.

2005-01-01

The different aspects linked to the use of nuclear, radiological, biological and or chemical weapons are gathered in this work. They concern history, fundamental aspect, diagnosis, therapy and prevention. The part devoted to the nuclear aspect concern the accidents in relation with ionizing radiations, the radiation syndrome, the contribution and limits of dosimetry, the treatment of medullary aplasia, the evaluation and treatment of an internal contamination, new perspectives on the use of cytokine for the treatment of accidental irradiated persons, alternative to the blood transfusion. (N.C.)

MIMO Techniques for Jamming Threat Suppression in Vehicular Networks

Directory of Open Access Journals (Sweden)

Dimitrios Kosmanos

2016-01-01

Full Text Available Vehicular ad hoc networks have emerged as a promising field of research and development, since they will be able to accommodate a variety of applications, ranging from infotainment to traffic management and road safety. A specific security-related concern that vehicular ad hoc networks face is how to keep communication alive in the presence of radio frequency jamming, especially during emergency situations. Multiple Input Multiple Output techniques are proven to be able to improve some crucial parameters of vehicular communications such as communication range and throughput. In this article, we investigate how Multiple Input Multiple Output techniques can be used in vehicular ad hoc networks as active defense mechanisms in order to avoid jamming threats. For this reason, a variation of spatial multiplexing is proposed, namely, vSP4, which achieves not only high throughput but also a stable diversity gain upon the interference of a malicious jammer.

Threat modeling designing for security

CERN Document Server

Shostack, Adam

2014-01-01

Adam Shostack is responsible for security development lifecycle threat modeling at Microsoft and is one of a handful of threat modeling experts in the world. Now, he is sharing his considerable expertise into this unique book. With pages of specific actionable advice, he details how to build better security into the design of systems, software, or services from the outset. You'll explore various threat modeling approaches, find out how to test your designs against threats, and learn effective ways to address threats that have been validated at Microsoft and other top companies. Systems secur

Evaluative threat and ambulatory blood pressure: cardiovascular effects of social stress in daily experience.

Science.gov (United States)

Smith, Timothy W; Birmingham, Wendy; Uchino, Bert N

2012-11-01

Physiological effects of social evaluation are central in models of psychosocial influences on physical health. Experimental manipulations of evaluative threat evoke substantial cardiovascular and neuroendocrine responses in laboratory studies, but only preliminary evidence is available regarding naturally occurring evaluative threats in daily life. In such nonexperimental ambulatory studies, it is essential to distinguish effects of evaluative threat from related constructs known to alter stress, such as ability perceptions and concerns about appearance. 94 married, working couples (mean age 29.2 years) completed a 1-day (8 a.m. to 10 p.m.) ambulatory blood pressure protocol with random interval-contingent measurements using a Suntech monitor and Palm Pilot-based measures of control variables and momentary experiences of social-evaluative threat, concerns about appearance, and perceived ability. In hierarchical analyses for couples and multiple measurement occasions (Proc Mixed; SAS) and controlling individual differences (BMI, age, income) and potential confounds (e.g., posture, activity), higher reports of social-evaluative threat were associated with higher concurrent systolic (estimate = .87, SE = .34) and diastolic blood pressure (estimate = 1.06; SE = .26), both p social-evaluative threat remained significant when perceived ability and appearance concerns were controlled. Naturally occurring social-evaluative threat during daily activity is associated with increased systolic and diastolic blood pressure. Given associations between ambulatory blood pressure and risk of cardiovascular disease, the findings support conceptual models of threats to the social self as a potentially important influence on physical health.

Evaluation of DoD Biological Safety and Security Implementation

Science.gov (United States)

2016-04-27

advanced development, efficient production, and timely distribution. Critical Reagent Program products include antibodies, inactivated antigens , genomic...effects to the economy, communicability, low infectious dose, and a history of or current interest in weaponization based on threat reporting. The...unwarranted by the threat. Recommendation #3. Biological Personnel Reliability Program [BPRP] Maintain use of the BPRP tailored to bio -defense work; balance

Thinking about the threat of nuclear war: relevance to mental health

International Nuclear Information System (INIS)

Goldenberg, S.; LaCombe, S.; Levinson, D.; Parker, K.R.; Ross, C.; Sommers, F.

1985-01-01

Ontario students in grades 7-13 responded to open-ended and multiple-choice questions about future concerns, particularly unemployment, job/career plans, and the nuclear threat. Although worries about nuclear war were more frequent than those in other areas, their expression was associated with a sense of social efficacy rather than with feelings of helplessness

Unreliability as a Threat to Understanding Psychopathology: The Cautionary Tale of Attentional Bias

Science.gov (United States)

Rodebaugh, Thomas L.; Scullin, Rachel B.; Langer, Julia K.; Dixon, David J.; Huppert, Jonathan D.; Bernstein, Amit; Zvielli, Ariel; Lenze, Eric J.

2016-01-01

The use of unreliable measures constitutes a threat to our understanding of psychopathology, because advancement of science using both behavioral and biologically-oriented measures can only be certain if such measurements are reliable. Two pillars of NIMH’s portfolio – the Research Domain Criteria (RDoC) initiative for psychopathology and the target engagement initiative in clinical trials – cannot succeed without measures that possess the high reliability necessary for tests involving mediation and selection based on individual differences. We focus on the historical lack of reliability of attentional bias measures as an illustration of how reliability can pose a threat to our understanding. Our own data replicate previous findings of poor reliability for traditionally-used scores, which suggests a serious problem with the ability to test theories regarding attentional bias. This lack of reliability may also suggest problems with the assumption (in both theory and the formula for the scores) that attentional bias is consistent and stable across time. In contrast, measures accounting for attention as a dynamic process in time show good reliability in our data. The field is sorely in need of research reporting findings and reliability for attentional bias scores using multiple methods, including those focusing on dynamic processes over time. We urge researchers to test and report reliability of all measures, considering findings of low reliability not just as a nuisance but as an opportunity to modify and improve upon the underlying theory. Full assessment of reliability of measures will maximize the possibility that RDoC (and psychological science more generally) will succeed. PMID:27322741

How threats influence the evolutionary resolution of within-group conflict.

Science.gov (United States)

Cant, Michael A; Johnstone, Rufus A

2009-06-01

Most examples of cooperation in nature share a common feature: individuals can interact to produce a productivity benefit or fitness surplus, but there is conflict over how these gains are shared. A central question is how threats to exercise outside options influence the resolution of conflict within such cooperative associations. Here we show how a simple principle from economic bargaining theory, the outside option principle, can help to solve this problem in biological systems. According to this principle, outside options will affect the resolution of conflict only when the payoff of taking up these options exceeds the payoffs individuals can obtain from bargaining or negotiating within the group; otherwise, threats to exercise outside options are not credible and are therefore irrelevant. We show that previous attempts to incorporate outside options in synthetic models of reproductive conflict fail to distinguish between credible and incredible threats, and then we use the outside option principle to develop credible synthetic models in two contexts: reproductive skew and biparental care. A striking prediction of our analysis is that outside options are least relevant to the resolution of conflict in cooperative groups of kin and are most relevant in transient associations or interactions among nonrelatives. Our analysis shows a way to link the resolution of within-group conflict to the environmental setting in which it occurs, and it illuminates the role of threats in the evolution of social behavior.

Multiple daily fractionation in radiotherapy: biological rationale and preliminary clinical experiences

Energy Technology Data Exchange (ETDEWEB)

Arcangeli, G [Instituto Medico Scientifico, Rome (Italy). Dept. of Oncology; Mauro, F; Morelli, D; Nervi, C

1979-09-01

The biological bases of radiation dose fractionation are reviewed and discussed with special emphasis on reassortment. Experimental data on animal model systems are presented to clarify that reassortment has to be added to sublethal damage repair and reoxygenation in the rationale for an optimized radiotherapy course according to tumor cell kinetics. Clinical results on several human tumors treated with twice or thrice daily fractions are described. These results show that some clinically radioresistant tumors (especially if not characterized by a relatively long clinical doubling line) can be satisfactorily dealt with using multiple daily fractionation. Clinical observations indicate that a relatively high cumulative daily dose (200 + 150 + 150 rad) can be safely administered.

Countering Insider Threats

DEFF Research Database (Denmark)

Probst, Christian W.; Hunker, Jeffrey; Gollmann, Dieter

threat, and to develop a common vision of how an insider can be categorized as well as an integrated approach that allows a qualitative reasoning about the threat and the possibilities of attacks. This report gives an overview of the discussions and presentations during the week, as well as the outcome...

PORT SECURITY-Threats and Vulnerabilities

OpenAIRE

Kusi, Bernard

2015-01-01

The main objective of this thesis is to identify the threats and the vulnerabilities concerning Takoradi port, and finally recommend measure to overcome the identified threats and vul-nerabilities. Various categories of potential threats and vulnerabilities have been studied throughout the literature review. However, because each port presents a unique sets of threats and vulnerabilities, there was a need to look critically into how Takoradi port operations are being conducted in other to ide...

An examination of age-based stereotype threat about cognitive decline: Implications for stereotype threat research and theory development

Science.gov (United States)

Barber, Sarah J.

2017-01-01

“Stereotype threat” is often thought of as a singular construct, with moderators and mechanisms that are stable across groups and domains. However, this is not always true. To illustrate this, the current review focuses on the stereotype threat that older adults face about their cognitive abilities. Using Shapiro and Neuberg's (2007) Multi-Threat Framework, I first provide evidence that this is a self-concept threat, and not a group-reputation threat. Because this differs from the form(s) of threat experienced by other groups (e.g., the threat that minority students face about their intellectual abilities), the moderators of threat observed in other groups (i.e., group identification) do not always generalize to age-based stereotype threat about cognitive decline. Looking beyond the form(s) of threat elicited, this review also provides evidence that the mechanisms underlying stereotype threat effects may vary across the lifespan. Due to age-related improvements in emotion regulation abilities, stereotype threat does not seem to reduce older adults' executive control resources. Overall, this review highlights the need to approach the concept of stereotype threat with more granularity. This will allow us to design more effective stereotype threat interventions. It will also shed light on why certain effects “fail to replicate” across domains or groups. PMID:28073332

Today's threat and tomorrow's reaction

International Nuclear Information System (INIS)

Moore, L.R.

2002-01-01

Full text: The events of September 11 have only confirmed our past nightmares and warnings to industries, agencies, and governments. The threat of even more significant catastrophic attacks, using nuclear materials, was just as real ten years ago, as it is today. In many cases, our vulnerability remains the same as years ago. There is a dire need for all organizations to agree upon threats and vulnerabilities, and to implement appropriate protections, for nuclear materials or other 'means' to achieve an event of mass destruction. All appropriate organizations (industries, agencies, and governments) should be able to define, assess, and recognize international threats and vulnerabilities in the same manner. In complimentary fashion, the organizations should be able to implement safeguards against this consistent generic threat. On an international scale the same threats, and most vulnerabilities, pose high risks to all of these organizations and societies. Indeed, in today's world, the vulnerabilities of one nation may clearly pose great risk to another nation. Once threats and vulnerabilities are consistently recognized, we can begin to approach their mitigation in a more 'universal' fashion by the application of internationally recognized and accepted security measures. The path to recognition of these security measures will require agreement on many diverse issues. However, once there is general agreement, we can then proceed to the acquisition of diverse national and international resources with which to implement the security measures 'universally' to eliminate 'weak-links' in the chain of nuclear materials, on a truly international scale. I would like to discuss: developing a internationally acceptable 'generic' statement of threat, vulnerability assessment process, and security measure; proposing this international statement of threat, vulnerability assessment process, and appropriate security measures to organizations (industries, agencies, and governments

Turkey's response to threats of weapons of mass destruction

OpenAIRE

Al, Guray.

2001-01-01

Unlike most of its NATO allies, Turkey did not emerge from the Cold War with enhanced security. The acquisition of weapons of mass destruction (WMD) and ballistic missiles by its neighbors in the Middle Eastâ Iran, Iraq and Syriaâ creates a serious security concern for Turkey. This thesis analyzes the numerous threats posed to Turkey by its neighborsα nuclear, chemical and biological weapons programs and their ballistic missiles. It evaluates Turkeyαs defense options to counter these thre...

Turkey’s Response to Threats of Weapons of Mass Destruction

Science.gov (United States)

2001-12-01

categories of unconventional weapons and was prepared to invest enormous financial and human resources to achieve this goal. 5 Iraqi attempts to seek...Ministry of Defense White Paper of 2001 defines “Religious Fundementalism ” among the internal threats directed against Turkey’s security in the post...Therefore, Syria will likely continue to develop an extensive chemical and biological weapons arsenal and will also invest in upgrading the accuracy of

Consequences of a changing CBRN threat

International Nuclear Information System (INIS)

Medema, J.

2009-01-01

The OPCW now counts 186 member States. Member States that possessed chemical weapons (CW) are destroying those weapons, albeit at a slow pace. In the coming decade most, if not all, of the 100.000 + tons of CW from the previous century will have been destroyed. Of the 12± States, not part of the OPCW, four of them potentially have CW but their quantities are restricted to less than 1000 tons. About one kg of the more potent nerve agent or Mustard gas is required to produce on average one casualty amongst unprotected troops, 1000 tons potentially can produce 1 million casualties. Protection, passive chemical defense, is therefore mandatory. However, once a detection and protection system is in place, with a protection factor of say one thousand, the amount required to produce one casualty amongst troops in a military scenario becomes prohibitive. Furthermore, available CW quantities will have been reduced by pre-emptive airstrikes and the aggressor will have little chance to fully deploy his CW capability. The threat from massive CW with units facing several attacks per week has changed to incidental attacks on a smaller scale and with far lower frequency. This should have consequences for the chemical defense posture of the forces, Detection and protection are still required but the protection can have a lower capacity, less spares per individual. Because the number of incidents will be far lower it might be more cost effective to abandon contaminated equipment than to decontaminate it. As the number of CW casualties entering the military medical system will be small it might be better to find cures for diseases from biological weapons than to spent money on improved therapies for nerve agent or mustard. Although research in CW medical over the last 50 years was great, it has not produced a therapy for mustard or a significant improvement over the old therapy for nerve agent poisoning. With a declining CW threat the BW threat is on the rise, making a passive

Multiple levels of epigenetic control for bone biology and pathology.

Science.gov (United States)

Montecino, Martin; Stein, Gary; Stein, Janet; Zaidi, Kaleem; Aguilar, Rodrigo

2015-12-01

Multiple dimensions of epigenetic control contribute to regulation of gene expression that governs bone biology and pathology. Once confined to DNA methylation and a limited number of post-translational modifications of histone proteins, the definition of epigenetic mechanisms is expanding to include contributions of non-coding RNAs and mitotic bookmarking, a mechanism for retaining phenotype identity during cell proliferation. Together these different levels of epigenetic control of physiological processes and their perturbations that are associated with compromised gene expression during the onset and progression of disease, have contributed to an unprecedented understanding of the activities (operation) of the genomic landscape. Here, we address general concepts that explain the contribution of epigenetic control to the dynamic regulation of gene expression during eukaryotic transcription. This article is part of a Special Issue entitled Epigenetics and Bone. Copyright © 2015 Elsevier Inc. All rights reserved.

Evaluating Threats in Multinational Marine Ecosystems: A Coast Salish First Nations and Tribal Perspective.

Directory of Open Access Journals (Sweden)

Joseph K Gaydos

Full Text Available Despite the merit of managing natural resources on the scale of ecosystems, evaluating threats and managing risk in ecosystems that span multiple countries or jurisdictions can be challenging. This requires each government involved to consider actions in concert with actions being taken in other countries by co-managing entities. Multiple proposed fossil fuel-related and port development projects in the Salish Sea, a 16,925 km2 inland sea shared by Washington State (USA, British Columbia (Canada, and Indigenous Coast Salish governments, have the potential to increase marine vessel traffic and negatively impact natural resources. There is no legal mandate or management mechanism requiring a comprehensive review of the potential cumulative impacts of these development activities throughout the Salish Sea and across the international border. This project identifies ongoing and proposed energy-related development projects that will increase marine vessel traffic in the Salish Sea and evaluates the threats each project poses to natural resources important to the Coast Salish. While recognizing that Coast Salish traditions identify all species as important and connected, we used expert elicitation to identify 50 species upon which we could evaluate impact. These species were chosen because Coast Salish depend upon them heavily for harvest revenue or as a staple food source, they were particularly culturally or spiritually significant, or they were historically part of Coast Salish lifeways. We identified six development projects, each of which had three potential impacts (pressures associated with increased marine vessel traffic: oil spill, vessel noise and vessel strike. Projects varied in their potential for localized impacts (pressures including shoreline development, harbor oil spill, pipeline spill, coal dust accumulation and nearshore LNG explosion. Based on available published data, impact for each pressure/species interaction was rated as

[Health threats and health system crises. An approach to early warning and response. 2008 SESPAS Report].

Science.gov (United States)

Simón Soria, Fernando; Guillén Enríquez, Francisco Javier

2008-04-01

The world is changing more and faster than ever before. New diseases are coming to light each year, controlled diseases are reemerging as potential threats, and natural or man-made disasters are increasingly affecting human health. The "International Health Regulations (2005)" reflect the changes in the response of public health to this new situation. Surveillance of specific diseases and predefined control measures have been replaced by surveillance of public health events of international concern and control measures adapted to each situation. The public health events of international interest are characterized by their seriousness, predictability, the risk of international spread and potential for travel or trade restrictions. The development of the European Early Warning and Response System in 1998 and the creation of the European Center for Disease Prevention and Control in 2005 demonstrate political commitment in Europe, with early detection of and response to public health threats. However, timely risk evaluation and response at a national level requires improved data digitalization and accessibility, automatic notification processes, data analysis and dissemination of information, the combination of information from multiple sources and adaptation of public health services. The autonomous regions in Spain are initiating this adaptation process, but interoperability between systems and the development of guidelines for a coordinated response should be steered by the National Interregional Health Council and coordinated by the Ministry of Health. Efficient early warning systems of health threats that allow for a timely response and reduce uncertainty about information would help to minimize the risk of public health crises. The profile of public health threats is nonspecific. Early detection of threats requires access to information from multiple sources and efficient risk assessment. Key factors for improving the response to public health threats are the

Terrorist threats of nuclear facilities

International Nuclear Information System (INIS)

Jozsef Solymosi; Jozser Ronaky; Zoltan Levai; Arpad Vincze; Laszlo Foldi

2004-01-01

More than one year has passed since the terrible terrorist attacks against the United States. The tragic event fundamentally restructured our security policy approach and made requirements of countering terrorism a top priority of the 21st century. In one year a lot of studies were published and the majority of them analyses primarily the beginnings of terrorism then focus on the interrelations of causes and consequences of the attacks against the WTC. In most of the cases the authors can only put their questions most of which have remained unanswered to date. Meanwhile, in a short while after the attacks the secret assessments of threat levels of potential targets and areas were also prepared. One of the high priority fields is the issue of nuclear, biological, and chemical security, in short NBC-security. Here and now we focus on component N, that is the assessment techniques of nuclear security in short, without aiming at completeness. Our definite objective is to make non-expert readers understand - and present a concrete example as it is done in risk analysis - the real danger-level of nuclear facilities and especially the terrorist threat. Our objective is not to give tips to terrorists but to provide them with deterring arguments and at the same time calm worried people. In our communique we give an overview of international practice of nuclear antiterrorism and of preventive nuclear protection in Hungary. (author)

Regional management units for marine turtles: a novel framework for prioritizing conservation and research across multiple scales.

Science.gov (United States)

Wallace, Bryan P; DiMatteo, Andrew D; Hurley, Brendan J; Finkbeiner, Elena M; Bolten, Alan B; Chaloupka, Milani Y; Hutchinson, Brian J; Abreu-Grobois, F Alberto; Amorocho, Diego; Bjorndal, Karen A; Bourjea, Jerome; Bowen, Brian W; Dueñas, Raquel Briseño; Casale, Paolo; Choudhury, B C; Costa, Alice; Dutton, Peter H; Fallabrino, Alejandro; Girard, Alexandre; Girondot, Marc; Godfrey, Matthew H; Hamann, Mark; López-Mendilaharsu, Milagros; Marcovaldi, Maria Angela; Mortimer, Jeanne A; Musick, John A; Nel, Ronel; Pilcher, Nicolas J; Seminoff, Jeffrey A; Troëng, Sebastian; Witherington, Blair; Mast, Roderic B

2010-12-17

Resolving threats to widely distributed marine megafauna requires definition of the geographic distributions of both the threats as well as the population unit(s) of interest. In turn, because individual threats can operate on varying spatial scales, their impacts can affect different segments of a population of the same species. Therefore, integration of multiple tools and techniques--including site-based monitoring, genetic analyses, mark-recapture studies and telemetry--can facilitate robust definitions of population segments at multiple biological and spatial scales to address different management and research challenges. To address these issues for marine turtles, we collated all available studies on marine turtle biogeography, including nesting sites, population abundances and trends, population genetics, and satellite telemetry. We georeferenced this information to generate separate layers for nesting sites, genetic stocks, and core distributions of population segments of all marine turtle species. We then spatially integrated this information from fine- to coarse-spatial scales to develop nested envelope models, or Regional Management Units (RMUs), for marine turtles globally. The RMU framework is a solution to the challenge of how to organize marine turtles into units of protection above the level of nesting populations, but below the level of species, within regional entities that might be on independent evolutionary trajectories. Among many potential applications, RMUs provide a framework for identifying data gaps, assessing high diversity areas for multiple species and genetic stocks, and evaluating conservation status of marine turtles. Furthermore, RMUs allow for identification of geographic barriers to gene flow, and can provide valuable guidance to marine spatial planning initiatives that integrate spatial distributions of protected species and human activities. In addition, the RMU framework--including maps and supporting metadata--will be an

Regional Management Units for Marine Turtles: A Novel Framework for Prioritizing Conservation and Research across Multiple Scales

Science.gov (United States)

Wallace, Bryan P.; DiMatteo, Andrew D.; Hurley, Brendan J.; Finkbeiner, Elena M.; Bolten, Alan B.; Chaloupka, Milani Y.; Hutchinson, Brian J.; Abreu-Grobois, F. Alberto; Amorocho, Diego; Bjorndal, Karen A.; Bourjea, Jerome; Bowen, Brian W.; Dueñas, Raquel Briseño; Casale, Paolo; Choudhury, B. C.; Costa, Alice; Dutton, Peter H.; Fallabrino, Alejandro; Girard, Alexandre; Girondot, Marc; Godfrey, Matthew H.; Hamann, Mark; López-Mendilaharsu, Milagros; Marcovaldi, Maria Angela; Mortimer, Jeanne A.; Musick, John A.; Nel, Ronel; Pilcher, Nicolas J.; Seminoff, Jeffrey A.; Troëng, Sebastian; Witherington, Blair; Mast, Roderic B.

2010-01-01

Background Resolving threats to widely distributed marine megafauna requires definition of the geographic distributions of both the threats as well as the population unit(s) of interest. In turn, because individual threats can operate on varying spatial scales, their impacts can affect different segments of a population of the same species. Therefore, integration of multiple tools and techniques — including site-based monitoring, genetic analyses, mark-recapture studies and telemetry — can facilitate robust definitions of population segments at multiple biological and spatial scales to address different management and research challenges. Methodology/Principal Findings To address these issues for marine turtles, we collated all available studies on marine turtle biogeography, including nesting sites, population abundances and trends, population genetics, and satellite telemetry. We georeferenced this information to generate separate layers for nesting sites, genetic stocks, and core distributions of population segments of all marine turtle species. We then spatially integrated this information from fine- to coarse-spatial scales to develop nested envelope models, or Regional Management Units (RMUs), for marine turtles globally. Conclusions/Significance The RMU framework is a solution to the challenge of how to organize marine turtles into units of protection above the level of nesting populations, but below the level of species, within regional entities that might be on independent evolutionary trajectories. Among many potential applications, RMUs provide a framework for identifying data gaps, assessing high diversity areas for multiple species and genetic stocks, and evaluating conservation status of marine turtles. Furthermore, RMUs allow for identification of geographic barriers to gene flow, and can provide valuable guidance to marine spatial planning initiatives that integrate spatial distributions of protected species and human activities. In addition

Reducing Future International Chemical and Biological Dangers.

Energy Technology Data Exchange (ETDEWEB)

Haddal, Chad [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Bull, Diana L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hernandez, Patricia Marie [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Foley, John T. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2017-12-01

The International Biological and Chemical Threat Reduction Program at Sandia National Laboratories is developing a 15 - year technology road map in support the United States Government efforts to reduce international chemical and biological dangers . In 2017, the program leadership chartered an analysis team to explore dangers in the future international chemical and biological landscape through engagements with national security experts within and beyond Sandia to gain a multidisciplinary perspective on the future . This report offers a hi gh level landscape of future chemical and biological dangers based upon analysis of those engagements and provides support for further technology road map development.

Synthetic biology and biosecurity: challenging the "myths".

OpenAIRE

Jefferson, C; Lentzos, F; Marris, C

2014-01-01

15.10.14 KB. Ok to add published version to spiral, OA paper under cc by Synthetic biology, a field that aims to make biology easier to engineer, is routinely described as leading to an increase in the dual-use threat, i.e., the potential for the same scientific research to be used for peaceful purposes or misused for warfare or terrorism. Fears have been expressed that the de-skilling of biology, combined with online access to the genomic DNA sequences of pathogenic organisms an...

Counter-terrorism threat prediction architecture

Science.gov (United States)

Lehman, Lynn A.; Krause, Lee S.

2004-09-01

This paper will evaluate the feasibility of constructing a system to support intelligence analysts engaged in counter-terrorism. It will discuss the use of emerging techniques to evaluate a large-scale threat data repository (or Infosphere) and comparing analyst developed models to identify and discover potential threat-related activity with a uncertainty metric used to evaluate the threat. This system will also employ the use of psychological (or intent) modeling to incorporate combatant (i.e. terrorist) beliefs and intent. The paper will explore the feasibility of constructing a hetero-hierarchical (a hierarchy of more than one kind or type characterized by loose connection/feedback among elements of the hierarchy) agent based framework or "family of agents" to support "evidence retrieval" defined as combing, or searching the threat data repository and returning information with an uncertainty metric. The counter-terrorism threat prediction architecture will be guided by a series of models, constructed to represent threat operational objectives, potential targets, or terrorist objectives. The approach would compare model representations against information retrieved by the agent family to isolate or identify patterns that match within reasonable measures of proximity. The central areas of discussion will be the construction of an agent framework to search the available threat related information repository, evaluation of results against models that will represent the cultural foundations, mindset, sociology and emotional drive of typical threat combatants (i.e. the mind and objectives of a terrorist), and the development of evaluation techniques to compare result sets with the models representing threat behavior and threat targets. The applicability of concepts surrounding Modeling Field Theory (MFT) will be discussed as the basis of this research into development of proximity measures between the models and result sets and to provide feedback in support of model

Stereotype threat and female communication styles.

Science.gov (United States)

von Hippel, Courtney; Wiryakusuma, Cindy; Bowden, Jessica; Shochet, Megan

2011-10-01

A large body of research has documented the performance-debilitating effects of stereotype threat for individuals, but there is a paucity of research exploring interpersonal consequences of stereotype threat. Two experiments tested the hypothesis that stereotype threat would change the style in which women communicate. Results indicate that women who experience stereotype threat regarding leadership abilities react against the stereotype by adopting a more masculine communication style. Study 2 provides evidence that self-affirmation eliminates this effect of stereotype threat on women's communication styles. A third study demonstrates an ironic consequence of this effect of stereotype threat on women's communication--when women under stereotype threat adopt a more masculine communication style, they are rated as less warm and likeable, and evaluators indicate less willingness to comply with their requests. Theoretical and practical implications of these findings are discussed.

Fear, threat and efficacy in threat appeals: message involvement as a key mediator to message acceptance.

Science.gov (United States)

Cauberghe, Verolien; De Pelsmacker, Patrick; Janssens, Wim; Dens, Nathalie

2009-03-01

In a sample of 170 youngsters, the effect of two versions of a public service announcement (PSA) threat appeal against speeding, placed in four different contexts, on evoked fear, perceived threat (severity and probability of occurrence), perceived response efficacy and self-efficacy, message involvement and anti-speeding attitude and anti-speeding intention is investigated. Evoked fear and perceived threat and efficacy independently influence message involvement. Message involvement is a full mediator between evoked fear, perceived threat and efficacy perception on the one hand, and attitudes towards the message and behavioral intention to accept the message on the other. Speeding experience has a significantly negative impact on anti-speeding attitudes. Message and medium context threat levels and context thematic congruency have a significant effect on evoked fear and to a lesser extent on perceived threat.

Technologies to counter aviation security threats

Science.gov (United States)

Karoly, Steve

2017-11-01

The Aviation and Transportation Security Act (ATSA) makes TSA responsible for security in all modes of transportation, and requires that TSA assess threats to transportation, enforce security-related regulations and requirements, and ensure the adequacy of security measures at airports and other transportation facilities. Today, TSA faces a significant challenge and must address a wide range of commercial, military grade, and homemade explosives and these can be presented in an infinite number of configurations and from multiple vectors. TSA screens 2 million passengers and crew, and screens almost 5 million carry-on items and 1.2 million checked bags daily. As TSA explores new technologies for improving efficiency and security, those on the forefront of research and development can help identify unique and advanced methods to combat terrorism. Research and Development (R&D) drives the development of future technology investments that can address an evolving adversary and aviation threat. The goal is to rethink the aviation security regime in its entirety, and rather than focusing security at particular points in the enterprise, distribute security from the time a reservation is made to the time a passenger boards the aircraft. The ultimate objective is to reengineer aviation security from top to bottom with a continued focus on increasing security throughout the system.

A vulnerability assessment of 300 species in Florida: threats from sea level rise, land use, and climate change.

Directory of Open Access Journals (Sweden)

Joshua Steven Reece

Full Text Available Species face many threats, including accelerated climate change, sea level rise, and conversion and degradation of habitat from human land uses. Vulnerability assessments and prioritization protocols have been proposed to assess these threats, often in combination with information such as species rarity; ecological, evolutionary or economic value; and likelihood of success. Nevertheless, few vulnerability assessments or prioritization protocols simultaneously account for multiple threats or conservation values. We applied a novel vulnerability assessment tool, the Standardized Index of Vulnerability and Value, to assess the conservation priority of 300 species of plants and animals in Florida given projections of climate change, human land-use patterns, and sea level rise by the year 2100. We account for multiple sources of uncertainty and prioritize species under five different systems of value, ranging from a primary emphasis on vulnerability to threats to an emphasis on metrics of conservation value such as phylogenetic distinctiveness. Our results reveal remarkable consistency in the prioritization of species across different conservation value systems. Species of high priority include the Miami blue butterfly (Cyclargus thomasi bethunebakeri, Key tree cactus (Pilosocereus robinii, Florida duskywing butterfly (Ephyriades brunnea floridensis, and Key deer (Odocoileus virginianus clavium. We also identify sources of uncertainty and the types of life history information consistently missing across taxonomic groups. This study characterizes the vulnerabilities to major threats of a broad swath of Florida's biodiversity and provides a system for prioritizing conservation efforts that is quantitative, flexible, and free from hidden value judgments.

Modeling threat assessments of water supply systems using markov latent effects methodology.

Energy Technology Data Exchange (ETDEWEB)

Silva, Consuelo Juanita

2006-12-01

Recent amendments to the Safe Drinking Water Act emphasize efforts toward safeguarding our nation's water supplies against attack and contamination. Specifically, the Public Health Security and Bioterrorism Preparedness and Response Act of 2002 established requirements for each community water system serving more than 3300 people to conduct an assessment of the vulnerability of its system to a terrorist attack or other intentional acts. Integral to evaluating system vulnerability is the threat assessment, which is the process by which the credibility of a threat is quantified. Unfortunately, full probabilistic assessment is generally not feasible, as there is insufficient experience and/or data to quantify the associated probabilities. For this reason, an alternative approach is proposed based on Markov Latent Effects (MLE) modeling, which provides a framework for quantifying imprecise subjective metrics through possibilistic or fuzzy mathematics. Here, an MLE model for water systems is developed and demonstrated to determine threat assessments for different scenarios identified by the assailant, asset, and means. Scenario assailants include terrorists, insiders, and vandals. Assets include a water treatment plant, water storage tank, node, pipeline, well, and a pump station. Means used in attacks include contamination (onsite chemicals, biological and chemical), explosives and vandalism. Results demonstrated highest threats are vandalism events and least likely events are those performed by a terrorist.

At a global scale, do climate change threatened species also face a greater number of non-climatic threats?

Science.gov (United States)

Fortini, Lucas B.; Dye, Kaipo

2017-01-01

For many species the threats of climate change occur in a context of multiple existing threats. Given the current focus of global change ecology in identifying and understanding species vulnerable to climate change, we performed a global analysis to characterize the multi-threat context for species threatened by climate change. Utilizing 30,053 species from the International Union for Conservation of Nature’s (IUCN) Red List of Threatened Species, we sought to evaluate if species threatened by climate change are more likely threatened by a greater number of non-climatic threats than species not threatened by climate change. Our results show that species threatened by climate change are generally impacted by 21% more non-climatic threats than species not threatened by climate change. Across all species, this pattern is related to IUCN risk status, where endangered species threatened by climate change face 33% more non-climatic threats than endangered species not threatened by climate change. With the clear challenges of assessing current and projected impacts of climate change on species and ecosystems, research often requires reductionist approaches that result in downplaying this multi-threat context. This cautionary note bears relevance beyond climate change threatened species as we also

The global threat of antimicrobial resistance: science for intervention

Directory of Open Access Journals (Sweden)

I. Roca

2015-07-01

Full Text Available In the last decade we have witnessed a dramatic increase in the proportion and absolute number of bacterial pathogens resistant to multiple antibacterial agents. Multidrug-resistant bacteria are currently considered as an emergent global disease and a major public health problem. The B-Debate meeting brought together renowned experts representing the main stakeholders (i.e. policy makers, public health authorities, regulatory agencies, pharmaceutical companies and the scientific community at large to review the global threat of antibiotic resistance and come up with a coordinated set of strategies to fight antimicrobial resistance in a multifaceted approach. We summarize the views of the B-Debate participants regarding the current situation of antimicrobial resistance in animals and the food chain, within the community and the healthcare setting as well as the role of the environment and the development of novel diagnostic and therapeutic strategies, providing expert recommendations to tackle the global threat of antimicrobial resistance.

Sexual orientation and self-rated health: the role of social capital, offence, threat of violence, and violence.

Science.gov (United States)

Axelsson, Jakob; Modén, Birgit; Rosvall, Maria; Lindström, Martin

2013-07-01

To study the association between sexual orientation and self-rated health, including trust, offence, threat of violence, and violence. DESIGN/SETTING/PARTICIPANTS/MEASUREMENT: The 2008 Public Health Survey in Skåne is a cross-sectional postal questionnaire study. A total of 28,198 persons aged 18-80 years responded (55%). Logistic regressions analysed the association between sexual orientation and self-rated health. 27.4% of all men and 30.0% of all women rated their health as poor. Poor self-rated health was significantly more prevalent in higher age, among immigrants, people with lower education, low social support, low trust, experience of being offended, experience of threat of violence and violence, and bisexual and other orientation. Homosexual and bisexual men and women had higher age-adjusted odds ratios of having felt offended compared to heterosexual respondents. The odds ratios of low trust, threat of violence (men), and experience of violence (women) were significant for respondents with bisexual orientation but not for respondents with homosexual orientation. In the age-adjusted model, no significant association was observed between homosexual orientation and poor self-rated health among women. All other associations between sexual orientation and health were significant in the age-adjusted model but non-significant in the multiple models. Associations between sexual orientation and health disappear after multiple adjustments including trust and experience of offence, threat of violence, and violence. The study suggests that the group with bisexual orientation seems to be more exposed to low social capital (trust), threat of violence, and violence than the group with homosexual orientation.

Bio-threat microparticle simulants

Science.gov (United States)

Farquar, George Roy; Leif, Roald N

2012-10-23

A bio-threat simulant that includes a carrier and DNA encapsulated in the carrier. Also a method of making a simulant including the steps of providing a carrier and encapsulating DNA in the carrier to produce the bio-threat simulant.

Bio-threat microparticle simulants

Energy Technology Data Exchange (ETDEWEB)

Farquar, George Roy; Leif, Roald

2014-09-16

A bio-threat simulant that includes a carrier and DNA encapsulated in the carrier. Also a method of making a simulant including the steps of providing a carrier and encapsulating DNA in the carrier to produce the bio-threat simulant.

Synthetic biology and biosecurity: challenging the "myths".

Science.gov (United States)

Jefferson, Catherine; Lentzos, Filippa; Marris, Claire

2014-01-01

Synthetic biology, a field that aims to "make biology easier to engineer," is routinely described as leading to an increase in the "dual-use" threat, i.e., the potential for the same scientific research to be "used" for peaceful purposes or "misused" for warfare or terrorism. Fears have been expressed that the "de-skilling" of biology, combined with online access to the genomic DNA sequences of pathogenic organisms and the reduction in price for DNA synthesis, will make biology increasingly accessible to people operating outside well-equipped professional research laboratories, including people with malevolent intentions. The emergence of do-it-yourself (DIY) biology communities and of the student iGEM competition has come to epitomize this supposed trend toward greater ease of access and the associated potential threat from rogue actors. In this article, we identify five "myths" that permeate discussions about synthetic biology and biosecurity, and argue that they embody misleading assumptions about both synthetic biology and bioterrorism. We demonstrate how these myths are challenged by more realistic understandings of the scientific research currently being conducted in both professional and DIY laboratories, and by an analysis of historical cases of bioterrorism. We show that the importance of tacit knowledge is commonly overlooked in the dominant narrative: the focus is on access to biological materials and digital information, rather than on human practices and institutional dimensions. As a result, public discourse on synthetic biology and biosecurity tends to portray speculative scenarios about the future as realities in the present or the near future, when this is not warranted. We suggest that these "myths" play an important role in defining synthetic biology as a "promissory" field of research and as an "emerging technology" in need of governance.

On the possibility of multiple utilization of Bowen's Kale for neutron activation analysis of biological materials

International Nuclear Information System (INIS)

Marinov, V.M.; Lazarova, M.S.; Mihajlov, M.I.; Apostolov, D.

1977-01-01

The results of investigations related to the multiple utilization of Bowen's Kale in developing neutron-activation methods for determining microelements in biological materials carried out in recent years are presented. Bowen's Kale might be used as: (1) experimental material in the development of a method and its verification, i.e. as a test for biological materials; (2) a material where experimental conditions might be optimized; (3) a material for investigating the accuracy, reproducibility and the limit of proof at experimental conditions already defined; (4) a monitor; (5) a multielement volume reference standard for a number of microelements during their simultaneous determination and (6) a standard for verifying the authenticity of the results obtained. In this manner, a reliable criterion for comparison of the potentialities, the accuracy, reproducibility, the limits of proof and the authenticity of the neutron-activation methods of determining microelements in biological materials is introduced. (author)

Multivariate two-part statistics for analysis of correlated mass spectrometry data from multiple biological specimens.

Science.gov (United States)

Taylor, Sandra L; Ruhaak, L Renee; Weiss, Robert H; Kelly, Karen; Kim, Kyoungmi

2017-01-01

High through-put mass spectrometry (MS) is now being used to profile small molecular compounds across multiple biological sample types from the same subjects with the goal of leveraging information across biospecimens. Multivariate statistical methods that combine information from all biospecimens could be more powerful than the usual univariate analyses. However, missing values are common in MS data and imputation can impact between-biospecimen correlation and multivariate analysis results. We propose two multivariate two-part statistics that accommodate missing values and combine data from all biospecimens to identify differentially regulated compounds. Statistical significance is determined using a multivariate permutation null distribution. Relative to univariate tests, the multivariate procedures detected more significant compounds in three biological datasets. In a simulation study, we showed that multi-biospecimen testing procedures were more powerful than single-biospecimen methods when compounds are differentially regulated in multiple biospecimens but univariate methods can be more powerful if compounds are differentially regulated in only one biospecimen. We provide R functions to implement and illustrate our method as supplementary information CONTACT: sltaylor@ucdavis.eduSupplementary information: Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Many Species, Many Threats: A Composite Risk Assessment of Climate Impacts for Salmonids in the Pacific Northwest

Science.gov (United States)

Graham, M. C.; Greene, C.; Beechie, T. J.; Raymond, C.

2016-02-01

The life cycles of salmonid species span freshwater, estuarine, and marine environments, exposing these economically, ecologically, and culturally important species to a wide variety of climate change threats. The diverse life histories of salmonids make them differentially vulnerable to climate change based on their use of different habitat types and the variability in climate change threats across these habitat types. Previous studies have focused mainly on assessing the vulnerability of particular life stages for a few species. Hence, we lack a broad perspective on how multiple climate threats are expected to impact the entire salmonid community, which spend much of their lives in marine waters. This lack of knowledge hampers our ability to prioritize various adaptation strategies for salmonid conservation. In order to conduct a more extensive vulnerability study of salmonids, we performed a life cycle-based risk assessment of climate change threats for nine species of salmonids (species within Oncorhynchus, Salvelinus, and Prosopium genera) inhabiting the Skagit River watershed, which is subject to an array of climate impacts. Our risk assessment integrated projections of impacts from various climate threats in freshwater, estuarine, and marine ecosystems with expert-based assessments of species-specific sensitivity and exposure. We found that projections (multiple global climate models under moderate emission scenarios) of both changes in magnitude and frequency of three flow-related freshwater impacts (flooding, low flows, and suspended sediment pulses) were more severe than threats in estuarine and marine habitats for which we could obtain projections. Combining projections with expert-based sensitivity and exposure scores revealed that these three threats exhibited the highest risk across all species. Of the nine species, the four most vulnerable were Chinook and coho salmon, steelhead, and bull trout. Even though these salmonids spend much of their lives

Threats during sex work and association with mental health among young female sex workers in Hong Kong.

Science.gov (United States)

Mo, Phoenix K H; Mak, Winnie W S; Kwok, Yvonne T Y; Xin, Meiqi; Chan, Charlie W L; Yip, Louise W M

2018-08-01

Young female sex workers (YFSWs) are confronted with significant threats during sex work. The present cross-sectional study examined different levels of threats (i.e., threats to life and health, threats to humanity, threats to control of work and financial security, and the threats to future) experienced by 87 YFSWs (age 16-25) in Hong Kong, and identified their association with mental health (i.e., psychological well-being) together with other factors, including childhood trauma, self-efficacy, hope, and social support. Results showed that the participants encountered a significant number of threats. More than half reported that they had a condom removed by clients during sex (51.7%); or have been humililated by clients (51.7%). Because of sex work, about a quarter (25.3%) have had sexually transmitted disease, and respectively 10.3% and 12.6% have had abortion and unplanned pregnancy. The majority have had friends found out that they engaged in sex work (72.4%). They also showed a high level of worry about the various threats. Multiple linear regression analysis showed that childhood trauma (β = -.26) and worry about threats during sex work (β = -.22) were significantly negative predictors, while self-efficacy (β = .20) and hope (β = .27) were significantly positive predictors of mental health. Future services should improve YFSWs' skills to minimize potential threats during female sex work, address the structural correlates and relieve their worries, and empower them with more hope and self-efficacy in choosing clients.

At a global scale, do climate change threatened species also face a greater number of non-climatic threats?

Directory of Open Access Journals (Sweden)

Lucas B. Fortini

2017-07-01

Full Text Available For many species the threats of climate change occur in a context of multiple existing threats. Given the current focus of global change ecology in identifying and understanding species vulnerable to climate change, we performed a global analysis to characterize the multi-threat context for species threatened by climate change. Utilizing 30,053 species from the International Union for Conservation of Nature’s (IUCN Red List of Threatened Species, we sought to evaluate if species threatened by climate change are more likely threatened by a greater number of non-climatic threats than species not threatened by climate change. Our results show that species threatened by climate change are generally impacted by 21% more non-climatic threats than species not threatened by climate change. Across all species, this pattern is related to IUCN risk status, where endangered species threatened by climate change face 33% more non-climatic threats than endangered species not threatened by climate change. With the clear challenges of assessing current and projected impacts of climate change on species and ecosystems, research often requires reductionist approaches that result in downplaying this multi-threat context. This cautionary note bears relevance beyond climate change threatened species as we also found other (but not all anthropogenic threats are also similarly associated with more threats. Our findings serve as a reminder that ecological research should seriously consider these potential threat interactions, especially for species under elevated conservation concern.

Red swamp crayfish: biology, ecology and invasion - an overview

Directory of Open Access Journals (Sweden)

Tainã Gonçalves Loureiro

Full Text Available ABSTRACTAlien species have been transported and traded by humans for many centuries. However, with the era of globalization, biological invasions have reached notable magnitudes. Currently, introduction of alien species is one of the major threats to biodiversity and ecosystem functioning. The North American crayfish Procambarus clarkii is one of the most widely introduced freshwater species in the world, especially due to its high economic importance. It is responsible for great modifications in invaded environments causing irreparable ecological and economic damages. Its impressive ability to successfully colonize a wide range of environments is a consequence of its behavioural and biological characteristics that can adapt to features of the invaded location, conferring to this species a notable ecological plasticity. This review summarizes the available information regarding P. clarkii's biology and invasive dynamics around the world in order to contribute to the understanding of the threats posed by its establishment, as well as to support management and impact mitigation efforts.

DOE site-specific threat assessment

International Nuclear Information System (INIS)

West, D.J.; Al-Ayat, R.A.; Judd, B.R.

1985-01-01

A facility manager faced with the challenges of protecting a nuclear facility against potential threats must consider the likelihood and consequences of such threats, know the capabilities of the facility safeguards and security systems, and make informed decisions about the cost-effectivness of safeguards and security upgrades. To help meet these challenges, the San Francisco Operations Office of the Department of Energy, in conjunction with the Lawrence Livermore Laboratory, has developed a site-specific threat assessment approach and a quantitative model to improve the quality and consistency of site-specific threat assessment and resultant security upgrade decisions at sensitive Department of Energy facilities. 5 figs

Standoff Methods for the Detection of Threat Agents: A Review of Several Promising Laser-Based Techniques

Directory of Open Access Journals (Sweden)

J. Bruce Johnson

2014-01-01

Full Text Available Detection of explosives, explosive precursors, or other threat agents presents a number of technological challenges for optical sensing methods. Certainly detecting trace levels of threat agents against a complex background is chief among these challenges; however, the related issues of multiple target distances (from standoff to proximity and sampling time scales (from passive mines to rapid rate of march convoy protection for different applications make it unlikely that a single technique will be ideal for all sensing situations. A number of methods for spanning the range of optical sensor technologies exist which, when integrated, could produce a fused sensor system possessing a high level of sensitivity to threat agents and a moderate standoff real-time capability appropriate for portal screening of personnel or vehicles. In this work, we focus on several promising, and potentially synergistic, laser-based methods for sensing threat agents. For each method, we have briefly outlined the technique and report on the current level of capability.

The potential of TaqMan Array Cards for detection of multiple biological agents by real-time PCR.

Directory of Open Access Journals (Sweden)

Phillip A Rachwal

Full Text Available The TaqMan Array Card architecture, normally used for gene expression studies, was evaluated for its potential to detect multiple bacterial agents by real-time PCR. Ten PCR assays targeting five biological agents (Bacillus anthracis, Burkholderia mallei, Burkholderia pseudomallei, Francisella tularensis, and Yersinia pestis were incorporated onto Array Cards. A comparison of PCR performance of each PCR in Array Card and singleplex format was conducted using DNA extracted from pure bacterial cultures. When 100 fg of agent DNA was added to Array Card channels the following levels of agent detection (where at least one agent PCR replicate returned a positive result were observed: Y. pestis 100%, B. mallei & F. tularensis 93%; B. anthracis 71%; B. pseudomallei 43%. For B. mallei & pseudomallei detection the BPM2 PCR, which detects both species, outperformed PCR assays specific to each organism indicating identification of the respective species would not be reproducible at the 100 fg level. Near 100% levels of detection were observed when 100 fg of DNA was added to each PCR in singleplex format with singleplex PCRs also returning sporadic positives at the 10 fg per PCR level. Before evaluating the use of Array Cards for the testing of environmental and clinical sample types, with potential levels of background DNA and PCR inhibitors, users would therefore have to accept a 10-fold reduction in sensitivity of PCR assays on the Array Card format, in order to benefit for the capacity to test multiple samples for multiple agents. A two PCR per agent strategy would allow the testing of 7 samples for the presence of 11 biological agents or 3 samples for 23 biological agents per card (with negative control channels.

Mission Assurance, Threat Alert, Disaster Resiliency and Response (MATADRR) Product Reference Guide

Science.gov (United States)

2014-06-01

the world. Keystone implants the Google Earth KML ( Keyhole Markup Language) publishing interface to consume the Keystone Work Product sharing. Client...multiple Cores; display, close and archive incidents and work products; and monitor the health and status of the Core. Agreement Services are...to protect forces, mitigate threats, close protection gaps, and provide increased situational awareness by linking the disparate physical

Psychoanalysis and the nuclear threat

Energy Technology Data Exchange (ETDEWEB)

Levine, H.B.; Jacobs, D.; Rubin, L.J.

1988-01-01

{ital Psychoanalysis and the Nuclear Threat} provides coverage of the dynamic and clinical considerations that follow from life in the nuclear age. Of special clinical interest are chapters dealing with the developmental consequences of the nuclear threat in childhood, adolescence, and adulthood, and those exploring the technical issues raised by the occurrence in analytic and psychotherapeutic hours of material related to the nuclear threat. Additional chapters bring a psychoanalytic perspective to bear on such issues as the need to have enemies, silence as the real crime, love, work, and survival in the nuclear age, the relationship of the nuclear threat to issues of mourning and melancholia, apocalyptic fantasies, the paranoid process, considerations of the possible impact of gender on the nuclear threat, and the application of psychoanalytic thinking to nuclear arms strategy. Finally, the volume includes the first case report in the English language---albeit a brief psychotherapy---involving the treatment of a Hiroshima survivor.

Culture, threat, and mental illness stigma: identifying culture-specific threat among Chinese-American groups.

Science.gov (United States)

Yang, Lawrence H; Purdie-Vaughns, Valerie; Kotabe, Hiroki; Link, Bruce G; Saw, Anne; Wong, Gloria; Phelan, Jo C

2013-07-01

We incorporate anthropological insights into a stigma framework to elucidate the role of culture in threat perception and stigma among Chinese groups. Prior work suggests that genetic contamination that jeopardizes the extension of one's family lineage may comprise a culture-specific threat among Chinese groups. In Study 1, a national survey conducted from 2002 to 2003 assessed cultural differences in mental illness stigma and perceptions of threat in 56 Chinese-Americans and 589 European-Americans. Study 2 sought to empirically test this culture-specific threat of genetic contamination to lineage via a memory paradigm. Conducted from June to August 2010, 48 Chinese-American and 37 European-American university students in New York City read vignettes containing content referring to lineage or non-lineage concerns. Half the participants in each ethnic group were assigned to a condition in which the illness was likely to be inherited (genetic condition) and the rest read that the illness was unlikely to be inherited (non-genetic condition). Findings from Study 1 and 2 were convergent. In Study 1, culture-specific threat to lineage predicted cultural variation in stigma independently and after accounting for other forms of threat. In Study 2, Chinese-Americans in the genetic condition were more likely to accurately recall and recognize lineage content than the Chinese-Americans in the non-genetic condition, but that memorial pattern was not found for non-lineage content. The identification of this culture-specific threat among Chinese groups has direct implications for culturally-tailored anti-stigma interventions. Further, this framework might be implemented across other conditions and cultural groups to reduce stigma across cultures. Copyright © 2013 Elsevier Ltd. All rights reserved.

Sensor-guided threat countermeasure system

Science.gov (United States)

Stuart, Brent C.; Hackel, Lloyd A.; Hermann, Mark R.; Armstrong, James P.

2012-12-25

A countermeasure system for use by a target to protect against an incoming sensor-guided threat. The system includes a laser system for producing a broadband beam and means for directing the broadband beam from the target to the threat. The countermeasure system comprises the steps of producing a broadband beam and directing the broad band beam from the target to blind or confuse the incoming sensor-guided threat.

Multiple-Swarm Ensembles: Improving the Predictive Power and Robustness of Predictive Models and Its Use in Computational Biology.

Science.gov (United States)

Alves, Pedro; Liu, Shuang; Wang, Daifeng; Gerstein, Mark

2018-01-01

Machine learning is an integral part of computational biology, and has already shown its use in various applications, such as prognostic tests. In the last few years in the non-biological machine learning community, ensembling techniques have shown their power in data mining competitions such as the Netflix challenge; however, such methods have not found wide use in computational biology. In this work, we endeavor to show how ensembling techniques can be applied to practical problems, including problems in the field of bioinformatics, and how they often outperform other machine learning techniques in both predictive power and robustness. Furthermore, we develop a methodology of ensembling, Multi-Swarm Ensemble (MSWE) by using multiple particle swarm optimizations and demonstrate its ability to further enhance the performance of ensembles.

[Biological treatment of multiple sclerosis

DEFF Research Database (Denmark)

Sorensen, P.S.; Sellebjerg, F.

2008-01-01

In 1996 interferon (IFN)beta was the first biopharmaceutical product to be approved for the treatment of relapsing-remitting multiple sclerosis (MS). In 2006 the more potent monoclonal antibody natalizumab was approved. Presently, a number of monoclonal antibodies are being studied, including ale...

Autobiographical memory sources of threats in dreams.

Science.gov (United States)

Lafrenière, Alexandre; Lortie-Lussier, Monique; Dale, Allyson; Robidoux, Raphaëlle; De Koninck, Joseph

2018-02-01

Temporal sources of dream threats were examined through the paradigm of the Threat Simulation Theory. Two groups of young adults (18-24 years old), who did not experience severe threatening events in the year preceding their dream and reported a dream either with or without threats, were included. Participants (N = 119) kept a log of daily activities and a dream diary, indicating whether dream components referred to past experiences. The occurrence of oneiric threats correlated with the reporting of threats in the daily logs, their average severity, and the stress level experienced the day preceding the dream. The group whose dreams contained threats had significantly more references to temporal categories beyond one year than the group with dreams without threats. Our findings suggest that in the absence of recent highly negative emotional experiences, the threat simulation system selects memory traces of threatening events experienced in the past. Copyright © 2017 Elsevier Inc. All rights reserved.

Single versus multiple enemies and the impact on biological control of spider mites in cassava fields in West-Africa

NARCIS (Netherlands)

Onzo, A.; Sabelis, M.W.; Hanna, R.

2014-01-01

To determine whether to use single or multiple predator species for biological pest control requires manipulative field experiments. We performed such tests in Benin (West Africa) in cassava fields infested by the cassava green mite Mononychellus tanajoa, and the cotton red mite Oligonychus

Synthetic biology and biosecurity: challenging the ‘myths’

Directory of Open Access Journals (Sweden)

Catherine eJefferson

2014-08-01

Full Text Available Synthetic biology, a field that aims to ‘make biology easier to engineer’, is routinely described as leading to an increase in the ‘dual use’ threat, i.e. the potential for the same piece of scientific research to be ‘used’ for peaceful purposes or ‘misused’ for warfare or terrorism. Fears have been expressed that the ‘de-skilling’ of biology, combined with online access to the genomic DNA sequences of pathogenic organisms and the reduction in price for DNA synthesis, will make biology increasingly accessible to people operating outside well-equipped professional research laboratories, including people with malevolent intentions. The emergence of DIY biology communities and of the student iGEM competition has come to epitomize this supposed trend towards greater ease of access and the associated potential threat from rogue actors. In this article, we identify 5 ‘myths’ that permeate discussions about synthetic biology and biosecurity, and argue that they embody misleading assumptions about both synthetic biology and bioterrorism. We demonstrate how these myths are challenged by more realistic understandings of the scientific research currently being conducted in both professional and DIY laboratories, and by an analysis of historical cases of bioterrorism. We show that the importance of tacit knowledge is commonly overlooked in the dominant narrative: the focus is on access to biological materials and digital information, rather than on human practices and institutional dimensions. As a result, public discourse on synthetic biology and biosecurity tends to portray speculative scenarios about the future as realities in the present or the near future, when this is not warranted. We suggest that these ‘myths’ play an important role in defining synthetic biology as a ‘promissory’ field of research and as an ‘emerging technology’ in need of governance.

Synthetic Biology and Biosecurity: Challenging the “Myths”

Science.gov (United States)

Jefferson, Catherine; Lentzos, Filippa; Marris, Claire

2014-01-01

Synthetic biology, a field that aims to “make biology easier to engineer,” is routinely described as leading to an increase in the “dual-use” threat, i.e., the potential for the same scientific research to be “used” for peaceful purposes or “misused” for warfare or terrorism. Fears have been expressed that the “de-skilling” of biology, combined with online access to the genomic DNA sequences of pathogenic organisms and the reduction in price for DNA synthesis, will make biology increasingly accessible to people operating outside well-equipped professional research laboratories, including people with malevolent intentions. The emergence of do-it-yourself (DIY) biology communities and of the student iGEM competition has come to epitomize this supposed trend toward greater ease of access and the associated potential threat from rogue actors. In this article, we identify five “myths” that permeate discussions about synthetic biology and biosecurity, and argue that they embody misleading assumptions about both synthetic biology and bioterrorism. We demonstrate how these myths are challenged by more realistic understandings of the scientific research currently being conducted in both professional and DIY laboratories, and by an analysis of historical cases of bioterrorism. We show that the importance of tacit knowledge is commonly overlooked in the dominant narrative: the focus is on access to biological materials and digital information, rather than on human practices and institutional dimensions. As a result, public discourse on synthetic biology and biosecurity tends to portray speculative scenarios about the future as realities in the present or the near future, when this is not warranted. We suggest that these “myths” play an important role in defining synthetic biology as a “promissory” field of research and as an “emerging technology” in need of governance. PMID:25191649

Determining environmental causes of biological effects: the need for a mechanistic physiological dimension in conservation biology.

Science.gov (United States)

Seebacher, Frank; Franklin, Craig E

2012-06-19

The emerging field of Conservation Physiology links environmental change and ecological success by the application of physiological theory, approaches and tools to elucidate and address conservation problems. Human activity has changed the natural environment to a point where the viability of many ecosystems is now under threat. There are already many descriptions of how changes in biological patterns are correlated with environmental changes. The next important step is to determine the causative relationship between environmental variability and biological systems. Physiology provides the mechanistic link between environmental change and ecological patterns. Physiological research, therefore, should be integrated into conservation to predict the biological consequences of human activity, and to identify those species or populations that are most vulnerable.

Threat in Context: School Moderation of the Impact of Social Identity Threat on Racial/Ethnic Achievement Gaps

Science.gov (United States)

Hanselman, Paul; Bruch, Sarah K.; Gamoran, Adam; Borman, Geoffrey D.

2014-01-01

Schools with very few and relatively low-performing marginalized students may be most likely to trigger social identity threats (including stereotype threats) that contribute to racial disparities. We test this hypothesis by assessing variation in the benefits of a self-affirmation intervention designed to counteract social identity threat in a…

Threats: power, family mealtimes, and social influence.

Science.gov (United States)

Hepburn, Alexa; Potter, Jonathan

2011-03-01

One of the most basic topics in social psychology is the way one agent influences the behaviour of another. This paper will focus on threats, which are an intensified form of attempted behavioural influence. Despite the centrality to the project of social psychology, little attention has been paid to threats. This paper will start to rectify this oversight. It reviews early examples of the way social psychology handles threats and highlights key limitations and presuppositions about the nature and role of threats. By contrast, we subject them to a programme of empirical research. Data comprise video records of a collection of family mealtimes that include preschool children. Threats are recurrent in this material. A preliminary conceptualization of features of candidate threats from this corpus will be used as an analytic start point. A series of examples are used to explicate basic features and dimensions that build the action of threatening. The basic structure of the threats uses a conditional logic: if the recipient continues problem action/does not initiate required action then negative consequences will be produced by the speaker. Further analysis clarifies how threats differ from warnings and admonishments. Sequential analysis suggests threats set up basic response options of compliance or defiance. However, recipients of threats can evade these options by, for example, reworking the unpleasant upshot specified in the threat, or producing barely minimal compliance. The implications for broader social psychological concerns are explored in a discussion of power, resistance, and asymmetry; the paper ends by reconsidering the way social influence can be studied in social psychology. ©2010 The British Psychological Society.

Microbial Degradation of Forensic Samples of Biological Origin: Potential Threat to Human DNA Typing.

Science.gov (United States)

Dash, Hirak Ranjan; Das, Surajit

2018-02-01

Forensic biology is a sub-discipline of biological science with an amalgam of other branches of science used in the criminal justice system. Any nucleated cell/tissue harbouring DNA, either live or dead, can be used as forensic exhibits, a source of investigation through DNA typing. These biological materials of human origin are rich source of proteins, carbohydrates, lipids, trace elements as well as water and, thus, provide a virtuous milieu for the growth of microbes. The obstinate microbial growth augments the degradation process and is amplified with the passage of time and improper storage of the biological materials. Degradation of these biological materials carriages a huge challenge in the downstream processes of forensic DNA typing technique, such as short tandem repeats (STR) DNA typing. Microbial degradation yields improper or no PCR amplification, heterozygous peak imbalance, DNA contamination from non-human sources, degradation of DNA by microbial by-products, etc. Consequently, the most precise STR DNA typing technique is nullified and definite opinion can be hardly given with degraded forensic exhibits. Thus, suitable precautionary measures should be taken for proper storage and processing of the biological exhibits to minimize their decaying process by micro-organisms.

Fear, threat and efficacy in threat appeals: Message involvement as a key mediator to message acceptance

OpenAIRE

Cauberghe, Verolien; De Pelsmacker, Patrick; JANSSENS, Wim; Dens, Nathalie

2009-01-01

In a sample of 170 youngsters, the effect of two versions of a public service announcement (PSA) threat appeal against speeding, placed in four different contexts. on evoked fear, perceived threat (severity and probability of occurrence), perceived response efficacy and self-efficacy, message involvement and anti-speeding attitude and anti-speeding intention is investigated. Evoked fear and perceived threat and efficacy independently influence message involvement...

Exploring lipids with nonlinear optical microscopy in multiple biological systems

Science.gov (United States)

Alfonso-Garcia, Alba

Lipids are crucial biomolecules for the well being of humans. Altered lipid metabolism may give rise to a variety of diseases that affect organs from the cardiovascular to the central nervous system. A deeper understanding of lipid metabolic processes would spur medical research towards developing precise diagnostic tools, treatment methods, and preventive strategies for reducing the impact of lipid diseases. Lipid visualization remains a complex task because of the perturbative effect exerted by traditional biochemical assays and most fluorescence markers. Coherent Raman scattering (CRS) microscopy enables interrogation of biological samples with minimum disturbance, and is particularly well suited for label-free visualization of lipids, providing chemical specificity without compromising on spatial resolution. Hyperspectral imaging yields large datasets that benefit from tailored multivariate analysis. In this thesis, CRS microscopy was combined with Raman spectroscopy and other label-free nonlinear optical techniques to analyze lipid metabolism in multiple biological systems. We used nonlinear Raman techniques to characterize Meibum secretions in the progression of dry eye disease, where the lipid and protein contributions change in ratio and phase segregation. We employed similar tools to examine lipid droplets in mice livers aboard a spaceflight mission, which lose their retinol content contributing to the onset of nonalcoholic fatty-liver disease. We also focused on atherosclerosis, a disease that revolves around lipid-rich plaques in arterial walls. We examined the lipid content of macrophages, whose variable phenotype gives rise to contrasting healing and inflammatory activities. We also proposed new label-free markers, based on lifetime imaging, for macrophage phenotype, and to detect products of lipid oxidation. Cholesterol was also detected in hepatitis C virus infected cells, and in specific strains of age-related macular degeneration diseased cells by

Effect of evaluation threat on procrastination behavior.

Science.gov (United States)

Bui, Ngoc H

2007-06-01

The author evaluated the effects of evaluation apprehension and trait procrastination on behaviors. The author examined private university students from southern California (N = 72) on two independent variables: evaluation threat (manipulated) and trait procrastination (nonmanipulated). The author found a significant interaction effect between type of evaluation threat and level of trait procrastination on the number of days to complete an assigned essay. Post hoc analyses showed high trait procrastinators in the high evaluation threat group significantly delayed returning essays compared with those in the low evaluation threat group. Also, in the low evaluation threat group, low trait procrastinators delayed more than did high trait procrastinators. These results suggest that educators can reduce behavioral delays by increasing evaluation threat, depending on a student's level of trait procrastination.

Does imminent threat capture and hold attention?

Science.gov (United States)

Koster, Ernst H W; Crombez, Geert; Van Damme, Stefaan; Verschuere, Bruno; De Houwer, Jan

2004-09-01

According to models of attention and emotion, threat captures and holds attention. In behavioral tasks, robust evidence has been found for attentional holding but not for attentional capture by threat. An important explanation for the absence of attentional capture effects is that the visual stimuli used posed no genuine threat. The present study investigated whether visual cues that signal an aversive white noise can elicit attentional capture and holding effects. Cues presented in an attentional task were simultaneously provided with a threat value through an aversive conditioning procedure. Response latencies showed that threatening cues captured and held attention. These results support recent views on attention to threat, proposing that imminent threat captures attention in everyone. (c) 2004 APA, all rights reserved

Insider Threat to Computer Security at Nuclear Facilities

Energy Technology Data Exchange (ETDEWEB)

West, Rebecca Lynn [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2018-01-29

After completing this session, you should be able to: Describe the Insider Threat; Characterize the cyber insider threat; Describe preventive measures against the insider threat; Describe protective measures against the insider threat.

Prospects for improved detection of chemical, biological, radiological, and nuclear threats

Energy Technology Data Exchange (ETDEWEB)

Wuest, Craig R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hart, Brad [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Slezak, Thomas R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2012-07-31

Acquisition and use of Chemical, Biological, Radiological, and Nuclear (CBRN) weapons continue to be a major focus of concern form the security apparatus of nation states because of their potential for mass casualties when used by a determined adversary.

Microbiological air pollution of production room of the meat processing plant as a potential threat to the workers

Directory of Open Access Journals (Sweden)

Barbara Breza-Boruta

2015-12-01

Full Text Available Introduction. Production rooms of the meat plants are the specific environment that require constant monitoring of microbiological air purity. Bioaerosols pose a threat to the safety of produced food and a considerable risk to health of exposed workers. The aim of this study was to estimate the air microbiological pollution in production rooms of the meat processing plant and exposure of the workers to biological aerosol. Material and methods. Air samples were collected at 3 stands in production rooms during winter, with the compaction method using the impactor MAS-100. The total number of bacteria and moulds, Staphylococci and bacteria of the family Enterobacteriaceae were determined in the studied bioaerosol. The concentration of microorganisms was presented in the form of colony forming units in 1m3 of air. Results. The highest concentration of mesophylic bacteria was found at stand 1 – at the freezing tunnel; whereas the highest contamination with staphylococci and fungal aerosol was found in the room where several workers were employed at packing frozen food. Among determined fungi predominated moulds of the genera: Penicillium, Alternaria and Cladosporium. Also species of potentially pathogenic fungi which produce toxins and have allergizing properties were detected in the studied bioaerosol. Bacteria of the family Enterobacteriaceae, which also may cause many infavourable health effects in exposed people, occurred at all stands. Conclusion. The concentration level and microbial composition in the inhaled air make valuable information for determination of occupational risk and a potential threat to workers of their workstations. Potentially pathogenic microorganisms present in the studied air (staphylococci, bacteria of the family Enterobacteriaceae and some moulds according to the Directive 2000/54/EC l belong to the 2nd group of risk and threat of harmful biological agents. Identification of biological threats makes it easier for the

The effects of perceived phenotypic racial stereotypicality and social identity threat on racial minorities' attitudes about police.

Science.gov (United States)

Kahn, Kimberly Barsamian; Lee, J Katherine; Renauer, Brian; Henning, Kris R; Stewart, Greg

2017-01-01

This study examines the role of perceived phenotypic racial stereotypicality and race-based social identity threat on racial minorities' trust and cooperation with police. We hypothesize that in police interactions, racial minorities' phenotypic racial stereotypicality may increase race-based social identity threat, which will lead to distrust and decreased participation with police. Racial minorities (Blacks, Latinos, Native Americans, and multi-racials) and Whites from a representative random sample of city residents were surveyed about policing attitudes. A serial multiple mediation model confirmed that racial minorities' self-rated phenotypic racial stereotypicality indirectly affected future cooperation through social identity threat and trust. Due to the lack of negative group stereotypes in policing, the model did not hold for Whites. This study provides evidence that phenotypic stereotypicality influences racial minorities' psychological experiences interacting with police.

THE IMPACT OF ANXIETY UPON COGNITION: PERSPECTIVES FROM HUMAN THREAT OF SHOCK STUDIES

Directory of Open Access Journals (Sweden)

Oliver Joe Robinson

2013-05-01

Full Text Available Anxiety disorders constitute a sizeable worldwide health burden with profound social and economic consequences. The symptoms are wide-ranging; from hyperarousal to difficulties with concentrating. This latter effect falls under the broad category of altered cognitive performance; in this review we examine studies quantifying such impacts of anxiety on cognition. Specifically, we focus on the translational threat of unpredictable shock paradigm, a method previously used to characterize emotional responses and defensive mechanisms that is now emerging as valuable tool for examining the interaction between anxiety and cognition. In particular, we compare the impact of threat of shock on cognition in humans to that of pathological anxiety disorders. We highlight that both threat of shock and anxiety disorders promote mechanisms associated with harm avoidance across multiple levels of cognition (from perception to attention to learning and executive function – a ‘hot’ cognitive function which can be both adaptive and maladaptive depending upon the circumstances. This mechanism comes at a cost to other functions such as working memory, but leaves some functions, such as planning, unperturbed. We also highlight a number of cognitive effects that differ across anxiety disorders and threat of shock. These discrepant effects are largely seen in ‘cold’ cognitive functions involving control mechanisms and may reveal boundaries between adaptive (e.g. response to threat and maladaptive (e.g. pathological anxiety. We conclude by raising a number of unresolved questions regarding the role of anxiety in cognition that may provide fruitful avenues for future research.

Research on simulation technology for CBRN threat assessment system. Prediction technology for atmospheric dispersion of CBRN materials

International Nuclear Information System (INIS)

Miura, Hiroaki; Yano, Masanori; Nakata, Mitsuhiro; Takeda, Masaki

2013-01-01

The technical survey is conducted on the CBRN (Chemical, Biological, Radiological and Nuclear) Threat Assessment System Simulation Technology. The dispersion property of CBRN materials is summarized, and the current simulation techniques for CBRN materials dispersion are described. The effects of advection-diffusion, sedimentation by the gravity, buoyancy and wash-out by rainfall on the dispersion property of CBRN materials should be considered in the simulation modeling. The concentration distribution of CBRN materials is predicted through the meteorological analysis, the flow analysis and the dispersion analysis, and the hazard map will be produced from that. A selection of simulation method, model, domain and number of computational grid points is necessary to perform the simulation, considering the balance between calculation cost and prediction accuracy. For construction of CBRN Threat Assessment System, it is important how to integrate the developed simulation element technologies and threat assessment technologies. (author)

How Is Existential Threat Related to Intergroup Conflict? Introducing the Multidimensional Existential Threat (MET) Model

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Hirschberger, Gilad; Ein-Dor, Tsachi; Leidner, Bernhard; Saguy, Tamar

2016-01-01

Existential threat lies at the heart of intergroup conflict, but the literature on existential concerns lacks clear conceptualization and integration. To address this problem, we offer a new conceptualization and measurement of existential threat. We establish the reliability and validity of our measure, and to illustrate its utility, we examine whether different existential threats underlie the association between political ideology and support for specific political policies. Study 1 (N = 798) established the construct validity of the scale, and revealed four distinct existential threats: personal death (PD), physical collective annihilation (PA), symbolic collective annihilation (SA), and past victimization (PV). Study 2 (N = 424) confirmed the 4-factor structure, and the convergent and discriminant validity of the scale. Study 3 (N = 170) revealed that the association between a hawkish political ideology and support for hardline policies was mediated by PV, whereas the association between a dovish political ideology and conciliatory policies was mediated by concerns over collective symbolic annihilation. Study 4 (N = 503) conceptually replicated the pattern of findings found in Study 3, and showed that at times of conflict, PA concerns also mediate the relationship between hawkish ideologies and support for hardline policies. In both Studies 3 and 4, when controlling for other threats, PD did not play a significant role. These results underscore the need to consider the multidimensional nature of existential threat, especially in the context of political conflict. PMID:27994561

Stereotype threat spillover: how coping with threats to social identity affects aggression, eating, decision making, and attention.

Science.gov (United States)

Inzlicht, Michael; Kang, Sonia K

2010-09-01

Stereotype threat spillover is a situational predicament in which coping with the stress of stereotype confirmation leaves one in a depleted volitional state and thus less likely to engage in effortful self-control in a variety of domains. We examined this phenomenon in 4 studies in which we had participants cope with stereotype and social identity threat and then measured their performance in domains in which stereotypes were not "in the air." In Study 1 we examined whether taking a threatening math test could lead women to respond aggressively. In Study 2 we investigated whether coping with a threatening math test could lead women to indulge themselves with unhealthy food later on and examined the moderation of this effect by personal characteristics that contribute to identity-threat appraisals. In Study 3 we investigated whether vividly remembering an experience of social identity threat results in risky decision making. Finally, in Study 4 we asked whether coping with threat could directly influence attentional control and whether the effect was implemented by inefficient performance monitoring, as assessed by electroencephalography. Our results indicate that stereotype threat can spill over and impact self-control in a diverse array of nonstereotyped domains. These results reveal the potency of stereotype threat and that its negative consequences might extend further than was previously thought. (PsycINFO Database Record (c) 2010 APA, all rights reserved).

Power and threat in intergroup conflict : How emotional and behavioral responses depend on amount and content of threat

NARCIS (Netherlands)

Kamans, Elanor; Otten, Sabine; Gordijn, Ernestine H.

We propose that in intergroup conflict threat content is important in understanding the reactions of those who experience threats the most: the powerless. Studies 1 and 2 show that powerless groups experience more threat than powerful groups, resulting in the experience of both more anger and fear.

Recent advances to address European Union Health Security from cross border chemical health threats.

Science.gov (United States)

Duarte-Davidson, R; Orford, R; Wyke, S; Griffiths, M; Amlôt, R; Chilcott, R

2014-11-01

The European Union (EU) Decision (1082/2013/EU) on serious cross border threats to health was adopted by the European Parliament in November 2013, in recognition of the need to strengthen the capacity of Member States to coordinate the public health response to cross border threats, whether from biological, chemical, environmental events or events which have an unknown origin. Although mechanisms have been in place for years for reporting cross border health threats from communicable diseases, this has not been the case for incidents involving chemicals and/or environmental events. A variety of collaborative EU projects have been funded over the past 10 years through the Health Programme to address gaps in knowledge on health security and to improve resilience and response to major incidents involving chemicals. This paper looks at the EU Health Programme that underpins recent research activities to address gaps in resilience, planning, responding to and recovering from a cross border chemical incident. It also looks at how the outputs from the research programme will contribute to improving public health management of transnational incidents that have the potential to overwhelm national capabilities, putting this into context with the new requirements as the Decision on serious cross border threats to health as well as highlighting areas for future development. Crown Copyright © 2014. Published by Elsevier Ltd. All rights reserved.

Comparing Effects of Biologic Agents in Treating Patients with Rheumatoid Arthritis: A Multiple Treatment Comparison Regression Analysis.

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Ingunn Fride Tvete

Full Text Available Rheumatoid arthritis patients have been treated with disease modifying anti-rheumatic drugs (DMARDs and the newer biologic drugs. We sought to compare and rank the biologics with respect to efficacy. We performed a literature search identifying 54 publications encompassing 9 biologics. We conducted a multiple treatment comparison regression analysis letting the number experiencing a 50% improvement on the ACR score be dependent upon dose level and disease duration for assessing the comparable relative effect between biologics and placebo or DMARD. The analysis embraced all treatment and comparator arms over all publications. Hence, all measured effects of any biologic agent contributed to the comparison of all biologic agents relative to each other either given alone or combined with DMARD. We found the drug effect to be dependent on dose level, but not on disease duration, and the impact of a high versus low dose level was the same for all drugs (higher doses indicated a higher frequency of ACR50 scores. The ranking of the drugs when given without DMARD was certolizumab (ranked highest, etanercept, tocilizumab/ abatacept and adalimumab. The ranking of the drugs when given with DMARD was certolizumab (ranked highest, tocilizumab, anakinra/rituximab, golimumab/ infliximab/ abatacept, adalimumab/ etanercept [corrected]. Still, all drugs were effective. All biologic agents were effective compared to placebo, with certolizumab the most effective and adalimumab (without DMARD treatment and adalimumab/ etanercept (combined with DMARD treatment the least effective. The drugs were in general more effective, except for etanercept, when given together with DMARDs.

Forecasting Lightning Threat Using WRF Proxy Fields

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McCaul, E. W., Jr.

2010-01-01

Objectives: Given that high-resolution WRF forecasts can capture the character of convective outbreaks, we seek to: 1. Create WRF forecasts of LTG threat (1-24 h), based on 2 proxy fields from explicitly simulated convection: - graupel flux near -15 C (captures LTG time variability) - vertically integrated ice (captures LTG threat area). 2. Calibrate each threat to yield accurate quantitative peak flash rate densities. 3. Also evaluate threats for areal coverage, time variability. 4. Blend threats to optimize results. 5. Examine sensitivity to model mesh, microphysics. Methods: 1. Use high-resolution 2-km WRF simulations to prognose convection for a diverse series of selected case studies. 2. Evaluate graupel fluxes; vertically integrated ice (VII). 3. Calibrate WRF LTG proxies using peak total LTG flash rate densities from NALMA; relationships look linear, with regression line passing through origin. 4. Truncate low threat values to make threat areal coverage match NALMA flash extent density obs. 5. Blend proxies to achieve optimal performance 6. Study CAPS 4-km ensembles to evaluate sensitivities.

Biological Criteria for Protection of U.S. Coral Reefs.

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Coral reef ecosystems are threatened by natural stressors, human activities, and natural stressors exacerbated by human activities. Under the U.S. Clean Water Act, States and Territories may guard against anthropogenic threats by adopting water quality standards based on biologic...

The role of perceived threat during emergency department cardiac evaluation and the age-posttraumatic stress disorder link.

Science.gov (United States)

Meli, Laura; Kautz, Marin; Julian, Jacob; Edmondson, Donald; Sumner, Jennifer A

2018-06-01

Evaluation for acute coronary syndrome (ACS) can trigger posttraumatic stress symptoms (PSS). Research suggests that younger, versus older, individuals may be at elevated risk for PSS after ACS evaluation. It has been proposed that younger individuals may be at greater risk because they perceive the suspected ACS event as more threatening than their older counterparts; however, this has yet to be tested. We examined whether perceived threat during ACS evaluation mediated the association between age and PSS after ACS evaluation in an observational cohort study of patients presenting to the emergency department (ED) with suspected ACS. Demographics and perceived threat were assessed in the ED. PSS were measured upon inpatient transfer or by phone 3 days later. The analytic sample comprised 871 adult participants. Multiple linear regression was used to examine (1) associations of age and perceived threat with PSS and (2) whether perceived threat mediated the association. Bootstrapping with percentile-based confidence intervals (CIs) was used to test the indirect effect. Each year of age was associated with lower PSS (b = - 0.12, p age was associated with lower perceived threat during ACS evaluation (b = - 0.05, p age differences in PSS development risk and the potential impact of age on threat perceptions may help inform ED treatment.

Establishing 'design basis threat' in Norway

International Nuclear Information System (INIS)

Maerli, M.B.; Naadland, E.; Reistad, O.

2002-01-01

Full text: INFCIRC 225 (Rev. 4) assumes that a state's physical protection system should be based on the state's evaluation of the threat, and that this should be reflected in the relevant legislation. Other factors should also be considered, including the state's emergency response capabilities and the existing and relevant measures of the state's system of accounting for and control of nuclear material. A design basis threat developed from an evaluation by the state of the threat of unauthorized removal of nuclear material and of sabotage of nuclear material and nuclear facilities is an essential element of a state's system of physical protection. The state should continuously review the threat, and evaluate the implications of any changes in that threat for the required levels and the methods of physical protection. As part of a national design basis threat assessment, this paper evaluates the risk of nuclear or radiological terrorism and sabotage in Norway. Possible scenarios are presented and plausible consequences are discussed with a view to characterize the risks. The need for more stringent regulatory requirements will be discussed, together with the (positive) impact of improved systems and procedures of physical protection on nuclear emergency planning. Special emphasis is placed on discussing the design basis threat for different scenarios in order to systemize regulatory efforts to update the current legislation, requirement for operators' contingency planning, response efforts and the need for emergency exercises. (author)

Insider Threat Mitigation Workshop Instructional Materials

Energy Technology Data Exchange (ETDEWEB)

Gibbs, Philip [Brookhaven National Lab. (BNL), Upton, NY (United States); Larsen, Robert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); O' Brien, Mike [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Rodriquez, Jose [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2008-01-01

Insiders represent a formidable threat to nuclear facilities. This set of workshop materials covers methodologies to analyze and approaches to mitigate the threat of an insider attempting abrupt theft of nuclear materials. This report is a compilation of workshop materials consisting of lectures on technical and administrative measures used in Physical Protection (PP) and Material Control and Accounting (MC&A) and methods for analyzing their effectiveness against a postulated insider threat.

Small Change Makes a Big Splash: The Role of Working Self-Concept in the Effects of Stereotype Threat on Memory.

Science.gov (United States)

Liu, Pei; Zhao, Fengqing; Zhang, Baoshan; Dang, Qingxiu

2017-10-03

Assuming that the principle of an active-self account holds true in real life, priming certain constructs could selectively activate a working self-concept, which in turn guides behavior. The current study involved two experiments that examined the relationships between stereotypic identity, working self-concept, and memory performance in older adults. Specifically, Study 1 tested whether a stereotype threat can affect older adults' working self-concept and memory performance. A modified Stroop color naming task and a separate recognition task showed that a stereotype threat prime altered the activation of the working self-concept and deteriorated the older adults' memory performance. Additionally, the working self-concept mediated the effect of stereotype threat on memory performance. Accordingly, we designed Study 2 to assess whether priming different identities can alter the working self-concept of the elderly and buffer the stereotype threat effect on memory performance. The results not only were the same as Study 1 but also revealed that activating multiple identities could mitigate the stereotype threat. These results support an active-self account and the efficacy of stereotype threat intervention. This intervention strategy may be able to be used in real situations to help the elderly alleviate stereotype threats and memory impairment.

Linking terrestrial and marine conservation planning and threats analysis.

Science.gov (United States)

Tallis, Heather; Ferdaña, Zach; Gray, Elizabeth

2008-02-01

The existence of the Gulf of Mexico dead zone makes it clear that marine ecosystems can be damaged by terrestrial inputs. Marine and terrestrial conservation planning need to be aligned in an explicit fashion to fully represent threats to marine systems. To integrate conservation planning for terrestrial and marine systems, we used a novel threats assessment that included 5 cross-system threats in a site-prioritization exercise for the Pacific Northwest coast ecoregion (U.S.A.). Cross-system threats are actions or features in one ecological realm that have effects on species in another realm. We considered bulkheads and other forms of shoreline hardening threats to terrestrial systems and roads, logging, agriculture, and urban areas threats to marine systems. We used 2 proxies of freshwater influence on marine environments, validated against a mechanistic model and field observations, to propagate land-based threats into marine sites. We evaluated the influence of cross-system threats on conservation priorities by comparing MARXAN outputs for 3 scenarios that identified terrestrial and marine priorities simultaneously: (1) no threats, (2) single-system threats, and (3) single- and cross-system threats. Including cross-system threats changed the threat landscape dramatically. As a result the best plan that included only single-system threats identified 323 sites (161,500 ha) at risk from cross-system threats. Including these threats changed the location of best sites. By comparing the best and sum solutions of the single- and cross-system scenarios, we identified areas ideal for preservation or restoration through integrated management. Our findings lend quantitative support to the call for explicitly integrated decision making and management action in terrestrial and marine ecosystems.

Probabilistic information transmission in a network of coupled oscillators reveals speed-accuracy trade-off in responding to threats

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Chicoli, Amanda; Paley, Derek A.

2016-11-01

Individuals in a group may obtain information from other group members about the environment, including the location of a food source or the presence of a predator. Here, we model how information spreads in a group using a susceptible-infected-removed epidemic model. We apply this model to a simulated shoal of fish using the motion dynamics of a coupled oscillator model, in order to test the biological hypothesis that polarized or aligned shoaling leads to faster and more accurate escape responses. The contributions of this study are the (i) application of a probabilistic model of epidemics to the study of collective animal behavior; (ii) testing the biological hypothesis that group cohesion improves predator escape; (iii) quantification of the effect of social cues on startle propagation; and (iv) investigation of the variation in response based on network connectivity. We find that when perfectly aligned individuals in a group are startled, there is a rapid escape by individuals that directly detect the threat, as well as by individuals responding to their neighbors. However, individuals that are not startled do not head away from the threat. In startled groups that are randomly oriented, there is a rapid, accurate response by individuals that directly detect the threat, followed by less accurate responses by individuals responding to neighbor cues. Over the simulation duration, however, even unstartled individuals head away from the threat. This study illustrates a potential speed-accuracy trade-off in the startle response of animal groups, in agreement with several previous experimental studies. Additionally, the model can be applied to a variety of group decision-making processes, including those involving higher-dimensional motion.

Bomb Threat Assessments. Fact Sheet

Science.gov (United States)

Tunkel, Ronald F.

2010-01-01

This information provides a brief, summary outline of how investigators should assess anonymous bomb threats at schools. Applying these principles may help administrators and law enforcement personnel accurately assess the viability and credibility of a threat and appropriately gauge their response. Any credible evidence provided by teachers or…

Stereotype threat in classroom settings: the interactive effect of domain identification, task difficulty and stereotype threat on female students' maths performance.

Science.gov (United States)

Keller, Johannes

2007-06-01

Stereotype threat research revealed that negative stereotypes can disrupt the performance of persons targeted by such stereotypes. This paper contributes to stereotype threat research by providing evidence that domain identification and the difficulty level of test items moderate stereotype threat effects on female students' maths performance. The study was designed to test theoretical ideas derived from stereotype threat theory and assumptions outlined in the Yerkes-Dodson law proposing a nonlinear relationship between arousal, task difficulty and performance. Participants were 108 high school students attending secondary schools. Participants worked on a test comprising maths problems of different difficulty levels. Half of the participants learned that the test had been shown to produce gender differences (stereotype threat). The other half learned that the test had been shown not to produce gender differences (no threat). The degree to which participants identify with the domain of maths was included as a quasi-experimental factor. Maths-identified female students showed performance decrements under conditions of stereotype threat. Moreover, the stereotype threat manipulation had different effects on low and high domain identifiers' performance depending on test item difficulty. On difficult items, low identifiers showed higher performance under threat (vs. no threat) whereas the reverse was true in high identifiers. This interaction effect did not emerge on easy items. Domain identification and test item difficulty are two important factors that need to be considered in the attempt to understand the impact of stereotype threat on performance.

Threats Management Throughout the Software Service Life-Cycle

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Erlend Andreas Gjære

2014-04-01

Full Text Available Software services are inevitably exposed to a fluctuating threat picture. Unfortunately, not all threats can be handled only with preventive measures during design and development, but also require adaptive mitigations at runtime. In this paper we describe an approach where we model composite services and threats together, which allows us to create preventive measures at design-time. At runtime, our specification also allows the service runtime environment (SRE to receive alerts about active threats that we have not handled, and react to these automatically through adaptation of the composite service. A goal-oriented security requirements modelling tool is used to model business-level threats and analyse how they may impact goals. A process flow modelling tool, utilising Business Process Model and Notation (BPMN and standard error boundary events, allows us to define how threats should be responded to during service execution on a technical level. Throughout the software life-cycle, we maintain threats in a centralised threat repository. Re-use of these threats extends further into monitoring alerts being distributed through a cloud-based messaging service. To demonstrate our approach in practice, we have developed a proof-of-concept service for the Air Traffic Management (ATM domain. In addition to the design-time activities, we show how this composite service duly adapts itself when a service component is exposed to a threat at runtime.

An overview of non-traditional nuclear threats

International Nuclear Information System (INIS)

Geelhood, B.D.; Wogman, N.A.

2005-01-01

In view of the terrorist threats to the United States, the country needs to consider new vectors and weapons related to nuclear and radiological threats against our homeland. The traditional threat vectors, missiles and bombers, have expanded to include threats arriving through the flow of commerce. The new commerce-related vectors include: sea cargo, truck cargo, rail cargo, air cargo, and passenger transport. The types of weapons have also expanded beyond nuclear warheads to include radiation dispersal devices (RDD) or 'dirty' bombs. The consequences of these nuclear and radiological threats are both economic and life threatening. The defense against undesirable materials entering our borders involves extensive radiation monitoring at ports of entry. The radiation and other signatures of potential nuclear and radiological threats are examined along with potential sensors to discover undesirable items in the flow of commerce. Techniques to improve radiation detection are considered. A strategy of primary and secondary screening is proposed to rapidly clear most cargo and carefully examine suspect cargo. (author)

Stereotype threat can reduce older adults' memory errors.

Science.gov (United States)

Barber, Sarah J; Mather, Mara

2013-01-01

Stereotype threat often incurs the cost of reducing the amount of information that older adults accurately recall. In the current research, we tested whether stereotype threat can also benefit memory. According to the regulatory focus account of stereotype threat, threat induces a prevention focus in which people become concerned with avoiding errors of commission and are sensitive to the presence or absence of losses within their environment. Because of this, we predicted that stereotype threat might reduce older adults' memory errors. Results were consistent with this prediction. Older adults under stereotype threat had lower intrusion rates during free-recall tests (Experiments 1 and 2). They also reduced their false alarms and adopted more conservative response criteria during a recognition test (Experiment 2). Thus, stereotype threat can decrease older adults' false memories, albeit at the cost of fewer veridical memories, as well.

Stereotype Threat, Test Anxiety, and Mathematics Performance

Science.gov (United States)

Tempel, Tobias; Neumann, Roland

2014-01-01

We investigated the combined effects of stereotype threat and trait test anxiety on mathematics test performance. Stereotype threat and test anxiety interacted with each other in affecting performance. Trait test anxiety predicted performance only in a diagnostic condition that prevented stereotype threat by stereotype denial. A state measure of…

CLASSIFICATION OF THREATS OF ECONOMIC SECURITY OF TAJIKISTAN

Directory of Open Access Journals (Sweden)

Blinichkina N. Yu.

2016-06-01

Full Text Available Ensuring of the state economic security suggests the fight against threats to such security. At the same time it is extremely important, firstly, to understand the essence of a threat to economic security and, secondly, to identify the common characteristics of threats allowing to systematize them and to determine the necessary measures to neutralize them on this basis. The traditional approach offers a classification of economic security threats depending on areas of their origin but it is impossible to determine the gravity of the threat to the economy and ways of neutralizing it.In this context we propose allocation of the economic threats to five groups depends on a number of characteristics that determine the level of their negative impact to the economy. Such classification of threats to economic security of Tajikistan helped to determine neutralization of which of them requires outside support, what requires priority within the framework of the strategy of economic security and national economic policy, and what does not require serious government efforts and may be neutralized automatically during neutralization of the other threats.

Excessive biologic response to IFNβ is associated with poor treatment response in patients with multiple sclerosis.

Directory of Open Access Journals (Sweden)

Richard A Rudick

Full Text Available BACKGROUND: Interferon-beta (IFNβ is used to inhibit disease activity in multiple sclerosis (MS, but its mechanisms of action are incompletely understood, individual treatment response varies, and biological markers predicting response to treatment have yet to be identified. METHODS: The relationship between the molecular response to IFNβ and treatment response was determined in 85 patients using a longitudinal design in which treatment effect was categorized by brain magnetic resonance imaging as good (n = 70 or poor response (n = 15. Molecular response was quantified using a customized cDNA macroarray assay for 166 IFN-regulated genes (IRGs. RESULTS: The molecular response to IFNβ differed significantly between patients in the pattern and number of regulated genes. The molecular response was strikingly stable for individuals for as long as 24 months, however, suggesting an individual 'IFN response fingerprint'. Unexpectedly, patients with poor response showed an exaggerated molecular response. IRG induction ratios demonstrated an exaggerated molecular response at both the first and 6-month IFNβ injections. CONCLUSION: MS patients exhibit individually unique but temporally stable biological responses to IFNβ. Poor treatment response is not explained by the duration of biological effects or the specific genes induced. Rather, individuals with poor treatment response have a generally exaggerated biological response to type 1 IFN injections. We hypothesize that the molecular response to type I IFN identifies a pathogenetically distinct subset of MS patients whose disease is driven in part by innate immunity. The findings suggest a strategy for biologically based, rational use of IFNβ for individual MS patients.

Biological interactions and cooperative management of multiple species.

Science.gov (United States)

Jiang, Jinwei; Min, Yong; Chang, Jie; Ge, Ying

2017-01-01

Coordinated decision making and actions have become the primary solution for the overexploitation of interacting resources within ecosystems. However, the success of coordinated management is highly sensitive to biological, economic, and social conditions. Here, using a game theoretic framework and a 2-species model that considers various biological relationships (competition, predation, and mutualism), we compute cooperative (or joint) and non-cooperative (or separate) management equilibrium outcomes of the model and investigate the effects of the type and strength of the relationships. We find that cooperation does not always show superiority to non-cooperation in all biological interactions: (1) if and only if resources are involved in high-intensity predation relationships, cooperation can achieve a win-win scenario for ecosystem services and resource diversity; (2) for competitive resources, cooperation realizes higher ecosystem services by sacrificing resource diversity; and (3) for mutual resources, cooperation has no obvious advantage for either ecosystem services or resource evenness but can slightly improve resource abundance. Furthermore, by using a fishery model of the North California Current Marine Ecosystem with 63 species and seven fleets, we demonstrate that the theoretical results can be reproduced in real ecosystems. Therefore, effective ecosystem management should consider the interconnection between stakeholders' social relationship and resources' biological relationships.

Cyber Security Threats to Safety-Critical, Space-Based Infrastructures

Science.gov (United States)

Johnson, C. W.; Atencia Yepez, A.

2012-01-01

Space-based systems play an important role within national critical infrastructures. They are being integrated into advanced air-traffic management applications, rail signalling systems, energy distribution software etc. Unfortunately, the end users of communications, location sensing and timing applications often fail to understand that these infrastructures are vulnerable to a wide range of security threats. The following pages focus on concerns associated with potential cyber-attacks. These are important because future attacks may invalidate many of the safety assumptions that support the provision of critical space-based services. These safety assumptions are based on standard forms of hazard analysis that ignore cyber-security considerations This is a significant limitation when, for instance, security attacks can simultaneously exploit multiple vulnerabilities in a manner that would never occur without a deliberate enemy seeking to damage space based systems and ground infrastructures. We address this concern through the development of a combined safety and security risk assessment methodology. The aim is to identify attack scenarios that justify the allocation of additional design resources so that safety barriers can be strengthened to increase our resilience against security threats.

49 CFR 1544.303 - Bomb or air piracy threats.

Science.gov (United States)

2010-10-01

... 49 Transportation 9 2010-10-01 2010-10-01 false Bomb or air piracy threats. 1544.303 Section 1544... AND COMMERCIAL OPERATORS Threat and Threat Response § 1544.303 Bomb or air piracy threats. (a) Flight.... (d) Notification. Upon receipt of any bomb threat against the security of a flight or facility, or...

Dual-Use Threat Assessment Framework - An Attempt to Quantify the Risk

International Nuclear Information System (INIS)

Stephen, E. R.; Lavigne, J. J.; Colton, B.

2007-01-01

Advances in the biosciences over the past decade have been rapid and transformative. While these advances offer significant benefit to society, they also provide very significant challenges in terms of security. Concerns over misuse and/or accidental use/release (dual use) although not new, are now being viewed through the security lens. There is a wide-spread view that public or private sector scientists, supported through investments by pharmaceutical, environmental and agricultural interests working in the fields that comprise biotechnology, posses the ability to assess the implications of their own work and work within a regime of self-control that is for the most part self-governing (codes of practice). On the other end of the spectrum are those that would codify or legislative control. All this is being done in the absence of a mechanism for quantifying the threat. This presentation will discuss the development of an assessment framework that addresses both actual and potential threats. The framework was developed based on available intelligence and other open source information along with interviews with those persons familiar with the concept of dual use and the multiple, sometimes competing agendas of a variety of interest groups. The framework will help to bring some clarity to the discussion and at the same time, help to inform those that are positioned to respond to the threat. (author)

Cyber threats within civil aviation

Science.gov (United States)

Heitner, Kerri A.

Existing security policies in civil aviation do not adequately protect against evolving cyber threats. Cybersecurity has been recognized as a top priority among some aviation industry leaders. Heightened concerns regarding cyber threats and vulnerabilities surround components utilized in compliance with the Federal Aviation Administration's (FAA) Next Generation Air Transportation (NextGen) implementation. Automated Dependent Surveillance-B (ADS-B) and Electronic Flight Bags (EFB) have both been exploited through the research of experienced computer security professionals. Civil aviation is essential to international infrastructure and if its critical assets were compromised, it could pose a great risk to public safety and financial infrastructure. The purpose of this research was to raise awareness of aircraft system vulnerabilities in order to provoke change among current national and international cybersecurity policies, procedures and standards. Although the education of cyber threats is increasing in the aviation industry, there is not enough urgency when creating cybersecurity policies. This project intended to answer the following questions: What are the cyber threats to ADS-B of an aircraft in-flight? What are the cyber threats to EFB? What is the aviation industry's response to the issue of cybersecurity and in-flight safety? ADS-B remains unencrypted while the FAA's mandate to implement this system is rapidly approaching. The cyber threat of both portable and non-portable EFB's have received increased publicity, however, airlines are not responding quick enough (if at all) to create policies for the use of these devices. Collectively, the aviation industry is not being proactive enough to protect its aircraft or airport network systems. That is not to say there are not leaders in cybersecurity advancement. These proactive organizations must set the standard for the future to better protect society and it's most reliable form of transportation.

GLOBAL WARMING: IS A NEW THREAT?

Energy Technology Data Exchange (ETDEWEB)

Ayca Eminoglu

2008-09-30

In the Post Cold War era, the concepts of ''security'', ''national security'', and ''international security'' have changed with regard to their contents and meanings. Such developments made states to renew their national security policies. Security is a special form of politics as well. All security issues are political problems but not all political conflicts are security issues. In the Post Cold War era, differentiating and increasing numbers of elements that constitutes threat changed the concept of threat and widen the capacity of security. In this term, many elements lost its effect of being a threat but also new threatening elements emerged. Environmental problems, human rights, mass migration, micro nationalism, ethnic conflicts, religious fundamentalism, contagious diseases, international terrorism, economic instabilities, drug and weapon smuggling and human trafficking are the new problems emerged in international security agenda. Environmental problems no longer take place in security issues and can be mentioned as a ''low security'' issue. They are threats to the global commons i.e. the oceans, the seas, the ozone layer and the climate system, which are life supports for mankind as a whole. Global warming is one of the most important environmental issues of our day that effects human life in every field and can be defined as a 'serious threat to international security'. Because of global warming, environmental changes will occur and these changes will cause conflicting issues in international relations. Because of global warming dwindling freshwater supplies, food shortages, political instability and other conflicts may take place. Some IR scholars see a need for global cooperation in order to face the threat. At the background of global warming and its effects, states have to get preventive measures and normally, each state form its own measures, therefore as a

Cyber Threats to Nuclear Infrastructures

Energy Technology Data Exchange (ETDEWEB)

Robert S. Anderson; Paul Moskowitz; Mark Schanfein; Trond Bjornard; Curtis St. Michel

2010-07-01

Nuclear facility personnel expend considerable efforts to ensure that their facilities can maintain continuity of operations against both natural and man-made threats. Historically, most attention has been placed on physical security. Recently however, the threat of cyber-related attacks has become a recognized and growing world-wide concern. Much attention has focused on the vulnerability of the electric grid and chemical industries to cyber attacks, in part, because of their use of Supervisory Control and Data Acquisition (SCADA) systems. Lessons learned from work in these sectors indicate that the cyber threat may extend to other critical infrastructures including sites where nuclear and radiological materials are now stored. In this context, this white paper presents a hypothetical scenario by which a determined adversary launches a cyber attack that compromises the physical protection system and results in a reduced security posture at such a site. The compromised security posture might then be malevolently exploited in a variety of ways. The authors conclude that the cyber threat should be carefully considered for all nuclear infrastructures.

Cyber Threats to Nuclear Infrastructures

International Nuclear Information System (INIS)

Anderson, Robert S.; Moskowitz, Paul; Schanfein, Mark; Bjornard, Trond; St. Michel, Curtis

2010-01-01

Nuclear facility personnel expend considerable efforts to ensure that their facilities can maintain continuity of operations against both natural and man-made threats. Historically, most attention has been placed on physical security. Recently however, the threat of cyber-related attacks has become a recognized and growing world-wide concern. Much attention has focused on the vulnerability of the electric grid and chemical industries to cyber attacks, in part, because of their use of Supervisory Control and Data Acquisition (SCADA) systems. Lessons learned from work in these sectors indicate that the cyber threat may extend to other critical infrastructures including sites where nuclear and radiological materials are now stored. In this context, this white paper presents a hypothetical scenario by which a determined adversary launches a cyber attack that compromises the physical protection system and results in a reduced security posture at such a site. The compromised security posture might then be malevolently exploited in a variety of ways. The authors conclude that the cyber threat should be carefully considered for all nuclear infrastructures.

Direct landfill disposal versus Mechanical Biological Treatment (MBT

Directory of Open Access Journals (Sweden)

Kulhawik Katarzyna

2016-09-01

Full Text Available After the implementation of a new waste management system, in which recycling is the most dominating process, landfill disposal still appears to be the most popular method of waste management in Poland, in which waste undergoes gradual decomposition and the influence of climate conditions, for example, air and atmospheric fallout, leads to the production of leachate and biogas emissions, which contribute to continual threats to the natural environment and humans. The above-mentioned threats can be limited by applying suitable techniques of waste treatment before its disposal. A technology that is oriented to these aims is a mechanical biological treatment (MBT before disposal.

The potential distribution of cassava mealybug (Phenacoccus manihoti, a threat to food security for the poor.

Directory of Open Access Journals (Sweden)

Tania Yonow

Full Text Available The cassava mealybug is a clear and present threat to the food security and livelihoods of some of the world's most impoverished citizens. Niche models, such as CLIMEX, are useful tools to indicate where and when such threats may extend, and can assist with planning for biosecurity and the management of pest invasions. They can also contribute to bioeconomic analyses that underpin the allocation of resources to alleviate poverty. Because species can invade and establish in areas with climates that are different from those that are found in their native range, it is essential to define robust range-limiting mechanisms in niche models. To avoid spurious results when applied to novel climates, it is necessary to employ cross-validation techniques spanning different knowledge domains (e.g., distribution data, experimental results, phenological observations. We build upon and update a CLIMEX niche model by Parsa et al. (PloS ONE 7: e47675, correcting inconsistent parameters and re-fitting it based on a careful examination of geographical distribution data and relevant literature. Further, we consider the role of irrigation, the known distribution of cassava production and a targeted review of satellite imagery to refine, validate and interpret our model and results. In so doing, we bring new insights into the potential spread of this invasive insect, enabling us to identify potential bio-security threats and biological control opportunities. The fit of the revised model is improved, particularly in relation to the wet and dry limits to establishment, and the parameter values are biologically plausible and accord with published scientific literature.

Degree of threat to the biological diversity in the Ilha Grande State Park (RJ) and guidelines for conservation.

Science.gov (United States)

Alho, C J R; Schneider, M; Vasconcellos, L A

2002-08-01

The State Park of Ilha Grande is only a part (5,594 hectares) of the entire island (19,300 hectares) which is located off the south coast of Rio de Janeiro state, between the cities of Mangaratiba and Angra dos Reis. Approximately half of the Park area (47%) is covered by dense Atlantic forest. The secondary forest growth is in a process of ecological succession close to attaining maturity (43%) and the remaining part (10%) is composed of human-altered areas (1%), rocky outcrops with herbaceous vegetation (7%), mangroves and beaches (2%). The fauna is well represented but already shows signs of degradation with introduced species. The analysis of the degree of threat has shown that the dense forest habitat has a relatively stable status of conservation while the secondary forest, the mangrove and the herbaceous vegetation on rocky outcrops (and their fauna) are categorized as vulnerable. The area altered by human occupation is considered threatened. Since the coastal area where Ilha Grande is located is well known for its beautiful scenery (known as the green coast, because of the contrast between the ocean and the Atlantic forest covering the Serra do Mar mountain chain). There is a strong possibility for tourism to become the means in which to achieve economic sustainability for conservation. Contradictorily, tourism is also the major threat to local biodiversity and its landscape units. Because tourism is not organized and controlled, during high season the numbers grow above local capacity, giving rise to a proliferation of hotels, guesthouses and camping grounds. The resulting untreated open sewage, random garbage disposal and other harmful activities form the major threats to biodiversity.

Identification of threats using linguistics-based knowledge extraction.

Energy Technology Data Exchange (ETDEWEB)

Chew, Peter A.

2008-09-01

One of the challenges increasingly facing intelligence analysts, along with professionals in many other fields, is the vast amount of data which needs to be reviewed and converted into meaningful information, and ultimately into rational, wise decisions by policy makers. The advent of the world wide web (WWW) has magnified this challenge. A key hypothesis which has guided us is that threats come from ideas (or ideology), and ideas are almost always put into writing before the threats materialize. While in the past the 'writing' might have taken the form of pamphlets or books, today's medium of choice is the WWW, precisely because it is a decentralized, flexible, and low-cost method of reaching a wide audience. However, a factor which complicates matters for the analyst is that material published on the WWW may be in any of a large number of languages. In 'Identification of Threats Using Linguistics-Based Knowledge Extraction', we have sought to use Latent Semantic Analysis (LSA) and other similar text analysis techniques to map documents from the WWW, in whatever language they were originally written, to a common language-independent vector-based representation. This then opens up a number of possibilities. First, similar documents can be found across language boundaries. Secondly, a set of documents in multiple languages can be visualized in a graphical representation. These alone offer potentially useful tools and capabilities to the intelligence analyst whose knowledge of foreign languages may be limited. Finally, we can test the over-arching hypothesis--that ideology, and more specifically ideology which represents a threat, can be detected solely from the words which express the ideology--by using the vector-based representation of documents to predict additional features (such as the ideology) within a framework based on supervised learning. In this report, we present the results of a three-year project of the same name. We believe

Threat Assessment in College Settings

Science.gov (United States)

Cornell, Dewey

2010-01-01

In 2007, the landscape of campus safety changed abruptly with the Virginia Tech shooting and the subsequent wave of anonymous threats in colleges across the country. In response to the tragedy, the Virginia state legislature mandated that every public institution of higher education establish a "threat assessment team." Both the FBI and the U.S.…

Cutaneous reactions in nuclear, biological and chemical warfare

Directory of Open Access Journals (Sweden)

Arora Sandeep

2005-03-01

Full Text Available Nuclear, biological and chemical warfare have in recent times been responsible for an increasing number of otherwise rare dermatoses. Many nations are now maintaining overt and clandestine stockpiles of such arsenal. With increasing terrorist threats, these agents of mass destruction pose a risk to the civilian population. Nuclear and chemical attacks manifest immediately while biological attacks manifest later. Chemical and biological attacks pose a significant risk to the attending medical personnel. The large scale of anticipated casualties in the event of such an occurrence would need the expertise of all physicians, including dermatologists, both military and civilian. Dermatologists are uniquely qualified in this respect. This article aims at presenting a review of the cutaneous manifestations in nuclear, chemical and biological warfare and their management.

How you perceive threat determines your behavior

Directory of Open Access Journals (Sweden)

Orlando Fernandes Junior

2013-10-01

Full Text Available The prioritization of processing emotional stimuli usually produces deleterious effects on task performance when it distracts from a task. One common explanation is that brain resources are consumed by emotional stimuli, diverting resources away from executing the task. Viewing unpleasant stimuli also generates defensive reactions, and these responses may be at least partially responsible for the effect of the emotional modulation observed in various reaction time (RT paradigms. We investigated whether modulatory effects on RT vary if we presented threat stimuli to prompt different defensive responses. To trigger different responses, we manipulated threat perception by moving the direction of threatening stimuli. Threatening or neutral stimuli were presented as distractors during a bar orientation discrimination task. The results demonstrated that threat stimuli directed towards the observer produced a decrease in RT; in contrast, threat stimuli directed away from the observer produced an increase in RT, when compared to neutral stimuli. Accelerated RT during direct threat stimuli was attributed to increased motor preparation resulting from strong activation of the defense response cascade. In contrast, no direct threat stimuli likely activated the defense cascade, but less intensively, prompting immobility. Different threat stimuli produced varying effects, which was interpreted as evidence that the modulation of RT by emotional stimuli represents the summation of attentional and motivational effects. Additionally, participants who had been previously exposed to diverse types of violent crime were more strongly influenced by direct threat stimuli. In sum, our data support the concept that emotions are indeed action tendencies.

Analysis of the Threat of Genetically Modified Organisms for Biological Warfare

Science.gov (United States)

2011-05-01

biological warfare. The primary focus of the framework are those aspects of the technology directly affecting humans by inducing virulent infectious disease...applications. Simple organisms such as fruit flies have been used to study the effects of genetic changes across generations. Transgenic mice are...Analysis * Multi-cell pathogens * Toxins (Chemical products of living cells.) * Fungi (Robust organism; no genetic manipulation needed

Negotiating the dynamics of uncomfortable knowledge: The case of dual use and synthetic biology

Science.gov (United States)

Marris, Claire; Jefferson, Catherine; Lentzos, Filippa

2014-01-01

Institutions need to ignore some knowledge in order to function. This is “uncomfortable knowledge” because it undermines the ability of those institutions to pursue their goals (Rayner, 2012). We identify three bodies of knowledge that are relevant to understandings of the dual use threat posed by synthetic biology but are excluded from related policy discussions. We demonstrate how these “unknown knowns” constitute uncomfortable knowledge because they disrupt the simplified worldview that underpins contemporary discourse on the potential misuse of synthetic biology by malign actors. We describe how these inconvenient truths have been systematically ignored and argue that this is because they are perceived as a threat by organisations involved in the promotion of synthetic biology as well as by those involved in managing biosecurity risks. This has led to a situation where concerns about the biosecurity threat posed by synthetic biology are not only exaggerated, but are, more importantly, misplaced. This, in turn, means that related policies are misdirected and unlikely to have much impact. We focus on the dynamics of discussions about synthetic biology and dual use to demonstrate how the same “knowns” that are denied or dismissed as “unknown knowns” in certain circumstances are sometimes mobilised as “known knowns” by the same category of actors in a different context, when this serves to sustain the goals of the individuals and institutions involved. Based on our own experience, we argue that negotiating the dynamics of uncomfortable knowledge is a difficult, but necessary, component of meaningful transdisciplinary collaborations. PMID:25484910

Information security practices emerging threats and perspectives

CERN Document Server

Awad, Ahmed; Woungang, Isaac

2017-01-01

This book introduces novel research targeting technical aspects of protecting information security and establishing trust in the digital space. New paradigms, and emerging threats and solutions are presented in topics such as application security and threat management; modern authentication paradigms; digital fraud detection; social engineering and insider threats; cyber threat intelligence; intrusion detection; behavioral biometrics recognition; hardware security analysis. The book presents both the important core and the specialized issues in the areas of protection, assurance, and trust in information security practice. It is intended to be a valuable resource and reference for researchers, instructors, students, scientists, engineers, managers, and industry practitioners. .

An Examination of Age-Based Stereotype Threat About Cognitive Decline.

Science.gov (United States)

Barber, Sarah J

2017-01-01

"Stereotype threat" is often thought of as a singular construct, with moderators and mechanisms that are stable across groups and domains. However, this is not always true. To illustrate this, the current review focuses on the stereotype threat that older adults face about their cognitive abilities. Drawing upon the multithreat framework, I first provide evidence that this is a self-concept threat and not a group-reputation threat. Because this differs from the forms of stereotype threat experienced by other groups (e.g., the threat that minority students face about their intellectual abilities), the moderators of stereotype threat observed in other groups (i.e., group identification) do not always generalize to age-based stereotype threat about cognitive decline. Looking beyond the forms of stereotype threat elicited, this review also provides evidence that the mechanisms underlying stereotype-threat effects may vary across the adult life span. Because of age-related improvements in emotion-regulation abilities, stereotype threat does not seem to reduce older adults' executive-control resources. Overall, this review highlights the need to approach the concept of stereotype threat with more granularity, allowing researchers to design more effective stereotype-threat interventions. It will also shed light on why certain stereotype threat effects "fail to replicate" across domains or groups.

Multiple Paternity in a Reintroduced Population of the Orinoco Crocodile (Crocodylus intermedius) at the El Frío Biological Station, Venezuela.

Science.gov (United States)

Rossi Lafferriere, Natalia A; Antelo, Rafael; Alda, Fernando; Mårtensson, Dick; Hailer, Frank; Castroviejo-Fisher, Santiago; Ayarzagüena, José; Ginsberg, Joshua R; Castroviejo, Javier; Doadrio, Ignacio; Vilá, Carles; Amato, George

2016-01-01

The success of a reintroduction program is determined by the ability of individuals to reproduce and thrive. Hence, an understanding of the mating system and breeding strategies of reintroduced species can be critical to the success, evaluation and effective management of reintroduction programs. As one of the most threatened crocodile species in the world, the Orinoco crocodile (Crocodylus intermedius) has been reduced to only a few wild populations in the Llanos of Venezuela and Colombia. One of these populations was founded by reintroduction at Caño Macanillal and La Ramera lagoon within the El Frío Biological Station, Venezuela. Twenty egg clutches of C. intermedius were collected at the El Frío Biological Station for incubation in the lab and release of juveniles after one year. Analyzing 17 polymorphic microsatellite loci from 335 hatchlings we found multiple paternity in C. intermedius, with half of the 20 clutches fathered by two or three males. Sixteen mothers and 14 fathers were inferred by reconstruction of multilocus parental genotypes. Our findings showed skewed paternal contributions to multiple-sired clutches in four of the clutches (40%), leading to an overall unequal contribution of offspring among fathers with six of the 14 inferred males fathering 90% of the total offspring, and three of those six males fathering more than 70% of the total offspring. Our results provide the first evidence of multiple paternity occurring in the Orinoco crocodile and confirm the success of reintroduction efforts of this critically endangered species in the El Frío Biological Station, Venezuela.

Multiple Paternity in a Reintroduced Population of the Orinoco Crocodile (Crocodylus intermedius at the El Frío Biological Station, Venezuela.

Directory of Open Access Journals (Sweden)

Natalia A Rossi Lafferriere

Full Text Available The success of a reintroduction program is determined by the ability of individuals to reproduce and thrive. Hence, an understanding of the mating system and breeding strategies of reintroduced species can be critical to the success, evaluation and effective management of reintroduction programs. As one of the most threatened crocodile species in the world, the Orinoco crocodile (Crocodylus intermedius has been reduced to only a few wild populations in the Llanos of Venezuela and Colombia. One of these populations was founded by reintroduction at Caño Macanillal and La Ramera lagoon within the El Frío Biological Station, Venezuela. Twenty egg clutches of C. intermedius were collected at the El Frío Biological Station for incubation in the lab and release of juveniles after one year. Analyzing 17 polymorphic microsatellite loci from 335 hatchlings we found multiple paternity in C. intermedius, with half of the 20 clutches fathered by two or three males. Sixteen mothers and 14 fathers were inferred by reconstruction of multilocus parental genotypes. Our findings showed skewed paternal contributions to multiple-sired clutches in four of the clutches (40%, leading to an overall unequal contribution of offspring among fathers with six of the 14 inferred males fathering 90% of the total offspring, and three of those six males fathering more than 70% of the total offspring. Our results provide the first evidence of multiple paternity occurring in the Orinoco crocodile and confirm the success of reintroduction efforts of this critically endangered species in the El Frío Biological Station, Venezuela.

Cumulative childhood interpersonal trauma is associated with reduced cortical differentiation between threat and non-threat faces in posttraumatic stress disorder adults.

Science.gov (United States)

Chu, Denise A; Bryant, Richard A; Gatt, Justine M; Harris, Anthony Wf

2018-03-01

Posttraumatic stress disorder and childhood trauma frequently co-occur. Both are associated with abnormal neural responses to salient emotion stimuli. As childhood trauma is a risk factor for posttraumatic stress disorder, differentiating between their neurophysiological effects is necessary to elucidate the neural pathways by which childhood trauma exposure contributes to increased posttraumatic stress disorder risks. Face-specific N170 evoked response potentials for backward-masked (non-conscious) and conscious threat (fear, angry) and non-threat (happy) faces were measured in 77 adults (18-64 years old, 64% women, 78% right-handed) symptomatic for posttraumatic stress disorder. Differences in N170 peak amplitudes for fear-versus-happy and angry-versus-happy faces at bilateral temporo-occipital (T5, T6) sites were computed. The effect of cumulative exposure to childhood interpersonal trauma, other childhood trauma, adult trauma, depression and posttraumatic stress disorder symptom severity on the N170 response was assessed using hierarchical multiple regression analyses. T5 N170 peak amplitudes for non-conscious fear-versus-happy faces were inversely related to cumulative childhood interpersonal trauma after accounting for socio-demographic, clinical symptom and other trauma factors. Posttraumatic stress disorder Avoidance was positively associated with N170 peak amplitudes for non-conscious fear-versus-happy faces, primarily due to reduced N170 responsivity to happy faces. Childhood interpersonal trauma exposure is associated with reduced discrimination between fear and happy faces, while avoidance symptom severity is associated with dampened responsivity to automatically processed happy faces in posttraumatic stress disorder adults. Results are discussed in terms of the likely contributions of impaired threat discrimination and deficient reward processing during neural processing of salient emotion stimuli, to increased risks of posttraumatic stress disorder

SIP threats detection system

OpenAIRE

Vozňák, Miroslav; Řezáč, Filip

2010-01-01

The paper deals with detection of threats in IP telephony, the authors developed a penetration testing system that is able to check up the level of protection from security threats in IP telephony. The SIP server is a key komponent of VoIP infrastructure and often becomes the aim of attacks and providers have to ensure the appropriate level of security. We have developed web-based penetration system which is able to check the SIP server if can face to the most common attacks.The d...

Biological agents with potential for misuse: a historical perspective and defensive measures

International Nuclear Information System (INIS)

Bhalla, Deepak K.; Warheit, David B.

2004-01-01

Biological and chemical agents capable of producing serious illness or mortality have been used in biowarfare from ancient times. Use of these agents has progressed from crude forms in early and middle ages, when snakes and infected cadavers were used as weapons in battles, to sophisticated preparations for use during and after the second World War. Cults and terrorist organizations have attempted the use of biological agents with an aim to immobilize populations or cause serious harm. The reasons for interest in these agents by individuals and organizations include relative ease of acquisition, potential for causing mass casualty or panic, modest financing requirement, availability of technology, and relative ease of delivery. The Centers for Disease Control and Prevention has classified Critical Biological Agents into three major categories. This classification was based on several criteria, which include severity of impact on human health, potential for delivery in a weapon, capacity to cause panic and special needs for development, and stockpiling of medication. Agents that could cause the greatest harm following deliberate use were placed in category A. Category B included agents capable of producing serious harm and significant mortality but of lower magnitude than category A agents. Category C included emerging pathogens that could be developed for mass dispersion in future and their potential as a major health threat. A brief description of the category A bioagents is included and the pathophysiology of two particularly prominent agents, namely anthrax and smallpox, is discussed in detail. The potential danger from biological agents and their ever increasing threat to human populations have created a need for developing technologies for their early detection, for developing treatment strategies, and for refinement of procedures to ensure survival of affected individuals so as to attain the ultimate goal of eliminating the threat from intentional use of

Biological agents with potential for misuse: a historical perspective and defensive measures.

Science.gov (United States)

Bhalla, Deepak K; Warheit, David B

2004-08-15

Biological and chemical agents capable of producing serious illness or mortality have been used in biowarfare from ancient times. Use of these agents has progressed from crude forms in early and middle ages, when snakes and infected cadavers were used as weapons in battles, to sophisticated preparations for use during and after the second World War. Cults and terrorist organizations have attempted the use of biological agents with an aim to immobilize populations or cause serious harm. The reasons for interest in these agents by individuals and organizations include relative ease of acquisition, potential for causing mass casualty or panic, modest financing requirement, availability of technology, and relative ease of delivery. The Centers for Disease Control and Prevention has classified Critical Biological Agents into three major categories. This classification was based on several criteria, which include severity of impact on human health, potential for delivery in a weapon, capacity to cause panic and special needs for development, and stockpiling of medication. Agents that could cause the greatest harm following deliberate use were placed in category A. Category B included agents capable of producing serious harm and significant mortality but of lower magnitude than category A agents. Category C included emerging pathogens that could be developed for mass dispersion in future and their potential as a major health threat. A brief description of the category A bioagents is included and the pathophysiology of two particularly prominent agents, namely anthrax and smallpox, is discussed in detail. The potential danger from biological agents and their ever increasing threat to human populations have created a need for developing technologies for their early detection, for developing treatment strategies, and for refinement of procedures to ensure survival of affected individuals so as to attain the ultimate goal of eliminating the threat from intentional use of

A review of research on common biological agents and their impact on environment

International Nuclear Information System (INIS)

Mashiatullah, A.; Qureshi, R.M.

2009-01-01

Biological agents are unique class of microorganisms which can be used to produce the disease in large populations of humans, animals and plants. If used for hostile purposes, any disease-causing microorganism could be considered a weapon. The use of biological agents is not a new concept and history is replete with examples of biological weapon use. Before the twenty century, biological warfare took on three main forms by deliberate poisoning of food and water with infectious material, use of microorganisms or toxins in some form of weapon system, and use of biologically inoculated fabrics. Four kinds of biological warfare agents are bacteria, viruses, rickettsiae, fungi. These are distinguished by being living organisms, that reproduce within their host victims, who then become contagious with a deadly multiplier effect, bacteria, viruses, or fungi or toxin found in nature can be used to kill or injure people. Biological agents may be used for an isolated assassination, as well as to cause incapacitation or death to thousands. These biological agents represent a dangerous military threat because they are alive, and are therefore unpredictable and uncontrollable once released. The act of bioterrorism can range from a simple hoax to the actual use of biological weapons. Biological agents have the potential to make an environment more dangerous over time. If the environment is contaminated, a long-term threat to the population could be created. This paper discusses common biological agents, their mode of action in living organisms and possible impact on the environment. (author)

Experimental estimation of snare detectability for robust threat monitoring.

Science.gov (United States)

O'Kelly, Hannah J; Rowcliffe, J Marcus; Durant, Sarah; Milner-Gulland, E J

2018-02-01

Hunting with wire snares is rife within many tropical forest systems, and constitutes one of the severest threats to a wide range of vertebrate taxa. As for all threats, reliable monitoring of snaring levels is critical for assessing the relative effectiveness of management interventions. However, snares pose a particular challenge in terms of tracking spatial or temporal trends in their prevalence because they are extremely difficult to detect, and are typically spread across large, inaccessible areas. As with cryptic animal targets, any approach used to monitor snaring levels must address the issue of imperfect detection, but no standard method exists to do so. We carried out a field experiment in Keo Seima Wildlife Reserve in eastern Cambodia with the following objectives: (1) To estimate the detection probably of wire snares within a tropical forest context, and to investigate how detectability might be affected by habitat type, snare type, or observer. (2) To trial two sets of sampling protocols feasible to implement in a range of challenging field conditions. (3) To conduct a preliminary assessment of two potential analytical approaches to dealing with the resulting snare encounter data. We found that although different observers had no discernible effect on detection probability, detectability did vary between habitat type and snare type. We contend that simple repeated counts carried out at multiple sites and analyzed using binomial mixture models could represent a practical yet robust solution to the problem of monitoring snaring levels both inside and outside of protected areas. This experiment represents an important first step in developing improved methods of threat monitoring, and such methods are greatly needed in southeast Asia, as well as in as many other regions.

A knowledge-based approach to estimating the magnitude and spatial patterns of potential threats to soil biodiversity.

Science.gov (United States)

Orgiazzi, Alberto; Panagos, Panos; Yigini, Yusuf; Dunbar, Martha B; Gardi, Ciro; Montanarella, Luca; Ballabio, Cristiano

2016-03-01

Because of the increasing pressures exerted on soil, below-ground life is under threat. Knowledge-based rankings of potential threats to different components of soil biodiversity were developed in order to assess the spatial distribution of threats on a European scale. A list of 13 potential threats to soil biodiversity was proposed to experts with different backgrounds in order to assess the potential for three major components of soil biodiversity: soil microorganisms, fauna, and biological functions. This approach allowed us to obtain knowledge-based rankings of threats. These classifications formed the basis for the development of indices through an additive aggregation model that, along with ad-hoc proxies for each pressure, allowed us to preliminarily assess the spatial patterns of potential threats. Intensive exploitation was identified as the highest pressure. In contrast, the use of genetically modified organisms in agriculture was considered as the threat with least potential. The potential impact of climate change showed the highest uncertainty. Fourteen out of the 27 considered countries have more than 40% of their soils with moderate-high to high potential risk for all three components of soil biodiversity. Arable soils are the most exposed to pressures. Soils within the boreal biogeographic region showed the lowest risk potential. The majority of soils at risk are outside the boundaries of protected areas. First maps of risks to three components of soil biodiversity based on the current scientific knowledge were developed. Despite the intrinsic limits of knowledge-based assessments, a remarkable potential risk to soil biodiversity was observed. Guidelines to preliminarily identify and circumscribe soils potentially at risk are provided. This approach may be used in future research to assess threat at both local and global scale and identify areas of possible risk and, subsequently, design appropriate strategies for monitoring and protection of soil

Chemical and biological weapons: new questions, new answers.

Science.gov (United States)

Hood, E

1999-01-01

The words "chemical and biological weapons" (CBW) send a shiver down most spines these days. With the end of the Cold War, the possibility of a massive nuclear confrontation appears remote, so today many popular doomsday scenarios center on the aggressive use of chemical or biological warfare by rogue nations or terrorist groups. As exaggerated as some of the accounts are, with CBW cast as the latest unseen, unstoppable enemy, the threat posed by these weapons is all too real, and growing. Images p931-a PMID:10585899

Applying the multi-threat framework of stereotype threat in the context of digital gaming

OpenAIRE

Pennington, C. R.; Kaye, L. K.; McCann, J. J.

2018-01-01

Females often report experiencing stigmatisation pertaining to their competency in digital gaming communities. Employing the principles of the multi-threat framework of stereotype threat, the current research examined the impact of gender-related stereotypes on females' gaming performance and related self-perceptions. In Experiment 1, 90 females were assigned to one of three conditions in which they were primed that their performance would be either diagnostic of their personal (self-as-targe...

Microbial Threats to Health. Emerging Infections: Microbial Threats to Health in the United States.

Science.gov (United States)

1992-10-01

and HIV in- fection. Although in the United States, HIV infection occurs predominately in male homosexuals and intravenous substance abusers, the rate...Davis. W. A., J. G. Kane, and V. G. Garagusi. 1978. Human Aerononas infections : a review of the literature and a case report of endocarditis ...AD-A257 841 AD____ GRANT NO: DAMD17-90-Z-0047 TITLE: MICROBIAL THREATS TO HEALTH SUBTITLE: REmerging Infections - Microbial Threats to Health in the

The DANGERTOME Personal Risk Threat Assessment Scale: An Instrument to Help Aid Immediate Threat Assessment for Counselors, Faculty, and Teachers

Science.gov (United States)

Juhnke, Gerald A.

2010-01-01

Threats of violence are not uncommon to counselors, faculty, or teachers. Each must be taken seriously, quickly analyzed, and safety procedures implemented. Yet, there exists a paucity of brief, face-to-face, assessments designed to aid threat assessment. To address this paucity, the author created The DANGERTOME Personal Risk Threat Assessment…

Hypersonic Threats to the Homeland

Science.gov (United States)

2017-03-28

ADAM) system . This ground based system protects 7 soldiers against rocket threats and utilizes a 10 kW laser with an effective range out to...early warning systems for response to hypersonic threats . The integration of directed energy defensive systems with Space Based Infrared Sensors (SBIRS...and early warning radars already in operation will save costs. By capitalizing on Terminal High Altitude Area Defense (THAAD) system capabilities

Key issues in body armour: threats, materials and design

OpenAIRE

Horsfall, Ian

2012-01-01

This chapter will examine the mechanics and materials of body armour in military, police and some security related applications to protect the wearer from penetrative threats. These threats will include battlefield threats such as shell fragments and high velocity bullets, and threats to law enforcement personnel such as handgun bullets and knives. Regardless of whether the threat is a high velocity bullet, or a knife, the essential requirements of body armour are the same; first an interacti...

Deflecting the trajectory and changing the narrative: how self-affirmation affects academic performance and motivation under identity threat.

Science.gov (United States)

Sherman, David K; Hartson, Kimberly A; Binning, Kevin R; Purdie-Vaughns, Valerie; Garcia, Julio; Taborsky-Barba, Suzanne; Tomassetti, Sarah; Nussbaum, A David; Cohen, Geoffrey L

2013-04-01

To the extent that stereotype and identity threat undermine academic performance, social psychological interventions that lessen threat could buffer threatened students and improve performance. Two studies, each featuring a longitudinal field experiment in a mixed-ethnicity middle school, examined whether a values affirmation writing exercise could attenuate the achievement gap between Latino American and European American students. In Study 1, students completed multiple self-affirmation (or control) activities as part of their regular class assignments. Latino American students, the identity threatened group, earned higher grades in the affirmation than control condition, whereas White students were unaffected. The effects persisted 3 years and, for many students, continued into high school by lifting their performance trajectory. Study 2 featured daily diaries to examine how the affirmation affected psychology under identity threat, with the expectation that it would shape students' narratives of their ongoing academic experience. By conferring a big-picture focus, affirmation was expected to broaden construals, prevent daily adversity from being experienced as identity threat, and insulate academic motivation from identity threat. Indeed, affirmed Latino American students not only earned higher grades than nonaffirmed Latino American students but also construed events at a more abstract than concrete level and were less likely to have their daily feelings of academic fit and motivation undermined by identity threat. Discussion centers on how social-psychological processes propagate themselves over time and how timely interventions targeting these processes can promote well-being and achievement.

Forum on Emerging Infectious Diseases Highlights Leading-Edge Research | Poster

Science.gov (United States)

Scientists and professionals from multiple governmental agencies recently gathered at NCI at Frederick for a forum on newly emerging infectious diseases, threats to public health, and ongoing efforts to study high-risk pathogens. During the one-day event, which was sponsored by the National Interagency Confederation for Biological Research’s Scientific Interaction Subcommittee, nine speakers from four agencies shared their research and their agencies’ endeavors to address current and future biological threats.

Failure to differentiate between threat-related and positive emotion cues in healthy adults with childhood interpersonal or adult trauma.

Science.gov (United States)

Chu, Denise A; Bryant, Richard A; Gatt, Justine M; Harris, Anthony W F

2016-07-01

Enhanced threat-related processing is associated with both elevated anxiety and childhood exposure to trauma. Given the paucity of evidence regarding the effects of childhood and adult trauma exposure on subsequent psychophysiological processes in the absence of psychopathology, we investigated the relative impacts of childhood interpersonal and non-interpersonal trauma, as well as adult trauma exposure on neural processing of threat in healthy adults. We measured peak amplitudes of the N170 face-sensitive visual ERP component response to non-conscious and conscious Angry (threat) versus Happy (non-threat, positive) and Neutral (non-threat baseline) faces at temporo-occipital sites (right-T6; left-T5) in 489 psychiatrically asymptomatic adults (aged 18-70 years, 54% women, 94% right-handed). N170 peak amplitude differences between Angry vs Happy or Neutral faces were calculated and subjected to hierarchical multiple regression analysis, with trauma types (childhood interpersonal, childhood non-interpersonal and adult trauma) entered as predictors of interest. After controlling for sociodemographic and health factors, N170 peak amplitudes for non-conscious Angry vs Happy faces were inversely associated with childhood interpersonal trauma at T6 and adult trauma exposure at T5. Post-hoc repeated measures ANOVA indicated that unlike adults without trauma exposure, trauma-exposed adults failed to show significantly reduced N170 responses to Happy relative to Angry faces during non-conscious processing. This suggests that childhood interpersonal and adult trauma exposure are associated with a failure to differentiate between non-threat or positive and threat-related emotion cues. This is consistent with generalised hypervigilance seen in PTSD, and suggests trauma exposure is associated with a generalized heightened responsivity to non-conscious non-threat or positive as well as threat-related emotion cues in psychiatrically healthy adults. Copyright © 2016 Elsevier Ltd

Gender, Stereotype Threat and Mathematics Test Scores

OpenAIRE

Ming Tsui; Xiao Y. Xu; Edmond Venator

2011-01-01

Problem statement: Stereotype threat has repeatedly been shown to depress womens scores on difficult math tests. An attempt to replicate these findings in China found no support for the stereotype threat hypothesis. Our math test was characterized as being personally important for the student participants, an atypical condition in most stereotype threat laboratory research. Approach: To evaluate the effects of this personal demand, we conducted three experiments. Results: ...

Economic impact profiling of CBRN events: focusing on biological incidents.

Science.gov (United States)

Cavallini, Simona; Bisogni, Fabio; Mastroianni, Marco

2014-12-01

Chemical, biological, radiological and nuclear (CBRN) incidents, both caused accidentally by human error or natural/technological events and determined intentionally as criminal/malicious/terroristic acts, have consequences that could be differently characterized. In the last years many efforts to analyze the economic impact of terrorist threat have been carried out, while researches specifically concerning CBRN events have not been extensively undertaken. This paper in particular aims at proposing a methodological approach for studying macro-level economic impact profiles of biological incidents caused by weaponized and non-weaponized materials. The suggested approach investigates the economic consequences of biological incidents according to two main dimensions: type of large-scale effect and persistence of effect. Biological incident economic impacts are analyzed taking into account the persistence of effect during time as short-term impact (i.e. immediately after the incident), medium-term impact (i.e. by a month) and long-term impact (i.e. by years). The costs due to preventive countermeasure against biological threats (e.g. prevention, protection and preparedness expenses) are not taken into account. To this purpose, information on the key features of past biological incidents can be used as case studies to try to build impact profiles taking into account the proposed two main dimensions. Consequence management and effect mitigation of CBRN emergencies and disasters may benefit from an ex ante definition of the impact profiling related to this kind of incidents. The final goal of this paper is to define an approach to organize information on possible biological events according to their impact profile for supporting more effective and efficient first responders' prompt actions and policy makers' strategic decisions after the event occurrence.

Conservatism and the neural circuitry of threat: economic conservatism predicts greater amygdala–BNST connectivity during periods of threat vs safety

Science.gov (United States)

Muftuler, L Tugan; Larson, Christine L

2018-01-01

Abstract Political conservatism is associated with an increased negativity bias, including increased attention and reactivity toward negative and threatening stimuli. Although the human amygdala has been implicated in the response to threatening stimuli, no studies to date have investigated whether conservatism is associated with altered amygdala function toward threat. Furthermore, although an influential theory posits that connectivity between the amygdala and bed nucleus of the stria terminalis (BNST) is important in initiating the response to sustained or uncertain threat, whether individual differences in conservatism modulate this connectivity is unknown. To test whether conservatism is associated with increased reactivity in neural threat circuitry, we measured participants’ self-reported social and economic conservatism and asked them to complete high-resolution fMRI scans while under threat of an unpredictable shock and while safe. We found that economic conservatism predicted greater connectivity between the BNST and a cluster of voxels in the left amygdala during threat vs safety. These results suggest that increased amygdala–BNST connectivity during threat may be a key neural correlate of the enhanced negativity bias found in conservatism. PMID:29126127

Humanizing Outgroups Through Multiple Categorization

Science.gov (United States)

Prati, Francesca; Crisp, Richard J.; Meleady, Rose; Rubini, Monica

2016-01-01

In three studies, we examined the impact of multiple categorization on intergroup dehumanization. Study 1 showed that perceiving members of a rival university along multiple versus simple categorical dimensions enhanced the tendency to attribute human traits to this group. Study 2 showed that multiple versus simple categorization of immigrants increased the attribution of uniquely human emotions to them. This effect was explained by the sequential mediation of increased individuation of the outgroup and reduced outgroup threat. Study 3 replicated this sequential mediation model and introduced a novel way of measuring humanization in which participants generated attributes corresponding to the outgroup in a free response format. Participants generated more uniquely human traits in the multiple versus simple categorization conditions. We discuss the theoretical implications of these findings and consider their role in informing and improving efforts to ameliorate contemporary forms of intergroup discrimination. PMID:26984016

Stereotype Threat Lowers Older Adults' Self-Reported Hearing Abilities.

Science.gov (United States)

Barber, Sarah J; Lee, Soohyoung Rain

2015-01-01

Although stereotype threat is a well-documented phenomenon, previous studies examining it in older adults have almost exclusively focused on objective cognitive outcomes. Considerably less attention has been paid to the impact of stereotype threat on older adults' subjective assessments of their own abilities or to the impact of stereotype threat in noncognitive domains. Older adults are stereotyped as having experienced not only cognitive declines, but physical declines as well. The current study tested the prediction that stereotype threat can negatively influence older adults' subjective hearing abilities. To test this, 115 adults (mean age 50.03 years, range 41-67) read either a positive or negative description about how aging affects hearing. All participants then answered a questionnaire in which they assessed their own hearing abilities. The impact of stereotype threat on self-reported hearing was moderated by chronological age. Participants in their 40s and early 50s were unaffected by the stereotype threat manipulation. In contrast, participants in their late 50s and 60s rated their hearing as being subjectively worse when under stereotype threat. The current study provides a clear demonstration that stereotype threat negatively impacts older adults' subjective assessments of their own abilities. It is also the first study to demonstrate an effect of stereotype threat within the domain of hearing. These results have important implications for researchers investigating age-related hearing decline. Stereotype threat can lead to overestimation of the prevalence of age-related hearing decline. It can also serve as a confounding variable when examining the psychosocial correlates of hearing loss. Because of this, researchers studying age-related hearing loss should aim to provide a stereotype threat-free testing environment and also include assessments of stereotype threat within their studies. © 2015 S. Karger AG, Basel.

Stereotype threat lowers older adults’ self-reported hearing abilities

Science.gov (United States)

Barber, Sarah J.; Lee, Soohyoung Rain

2016-01-01

Background Although stereotype threat is a well-documented phenomenon, previous studies examining it in older adults have almost exclusively focused on objective cognitive outcomes. Considerably less attention has been paid to the impact of stereotype threat on older adults’ subjective assessments of their own abilities or to the impact of stereotype threat in non-cognitive domains. Objective Older adults are stereotyped as having experienced not only cognitive declines, but physical declines as well. The current study tested the prediction that stereotype threat can negatively influence older adult's subjective hearing abilities. Methods To test this, 115 adults (M age = 50.02, range = 41-67) read either a positive or negative description about how aging affects hearing. All participants then answered a questionnaire in which they assessed their own hearing abilities. Results The impact of stereotype threat on self-reported hearing was moderated by chronological age. Participants in their 40's and early 50's were unaffected by the stereotype threat manipulation. In contrast, participants in their late 50's and 60's rated their hearing as being subjectively worse when under stereotype threat. Conclusion The current study provides a clear demonstration that stereotype threat negatively impacts older adults’ subjective assessments of their own abilities. It is also the first study to demonstrate an effect of stereotype threat within the domain of hearing. These results have important implications for researchers investigating age-related hearing decline. Stereotype threat can lead to overestimation of the prevalence of age-related hearing decline. It can also serve as a confounding variable when examining the psychosocial correlates of hearing loss. Because of this, researchers studying age-related hearing loss should aim to provide a stereotype-threat free testing environment and also include assessments of stereotype threat within their studies. PMID:26461273

49 CFR 1546.301 - Bomb or air piracy threats.

Science.gov (United States)

2010-10-01

... 49 Transportation 9 2010-10-01 2010-10-01 false Bomb or air piracy threats. 1546.301 Section 1546... Threat Response § 1546.301 Bomb or air piracy threats. No foreign air carrier may land or take off an airplane in the United States after receiving a bomb or air piracy threat against that airplane, unless the...

From Threat to Relief: Expressing Prejudice toward Atheists as a Self-Regulatory Strategy Protecting the Religious Orthodox from Threat

Science.gov (United States)

Kossowska, Małgorzata; Szwed, Paulina; Czernatowicz-Kukuczka, Aneta; Sekerdej, Maciek; Wyczesany, Miroslaw

2017-01-01

We claim that religious orthodoxy is related to prejudice toward groups that violate important values, i.e., atheists. Moreover, we suggest that expressing prejudice may efficiently reduce the threat posed by this particular group among people who hold high levels, but not low levels, of orthodox belief. We tested these assumptions in an experimental study in which, after being exposed to atheistic worldviews (value-threat manipulation), high and low orthodox participants were allowed (experimental condition) or not (control condition) to express prejudice toward atheists. Threat was operationalized by cardiovascular reactivity, i.e., heart rate (HR); the higher the HR index, the higher the threat. The results found that people who hold high (vs. low) levels of orthodox belief responded with increased HR after the threat manipulation. However, we observed decreased HR after the expression of prejudice toward atheists among highly orthodox participants compared to the control condition. We did not find this effect among people holding low levels of orthodox belief. Thus, we conclude that expressing prejudice toward this particular group may be an efficient strategy to cope with the threat posed by this group for highly orthodox people. The results are discussed in light of previous findings on religious beliefs and the self-regulatory function of prejudice. PMID:28611715

Using efficacy cues in persuasive health communication is more effective than employing threats - An experimental study of a vaccination intervention against Ebola.

Science.gov (United States)

Ort, Alexander; Fahr, Andreas

2018-04-10

persuasive health communication, especially regarding the interaction of threat perceptions and coping appraisals for fear and danger control processes. The Extended Parallel Process Model - being a current and often applied model to investigate the effects of fear appeals - suggests a multiplicative relationship between threat perceptions and coping perceptions Most studies applying conventional analysis strategies (e.g., [M] ANOVAs) indicate that perceptions and appraisals of threat and efficacy are not directly related to each other. What does this study add? It demonstrates the parallelism and interaction between threat appraisal and coping appraisal processes and demonstrates the usefulness of SEM in testing associations within the EPPM. It confirms the assumption of an important multiplicative association between threat and coping appraisals within the EPPM, while related cognitive processes still seem to operate independently. Adaptive responses to persuasive messages are mainly triggered using efficacy cues, not threat, which could also be triggered by promoting positive emotional experiences (e.g., gain-framing or entertainment education). © 2018 The British Psychological Society.

Biological Control Strategies for Mosquito Vectors of Arboviruses.

Science.gov (United States)

Huang, Yan-Jang S; Higgs, Stephen; Vanlandingham, Dana L

2017-02-10

Historically, biological control utilizes predatory species and pathogenic microorganisms to reduce the population of mosquitoes as disease vectors. This is particularly important for the control of mosquito-borne arboviruses, which normally do not have specific antiviral therapies available. Although development of resistance is likely, the advantages of biological control are that the resources used are typically biodegradable and ecologically friendly. Over the past decade, the advancement of molecular biology has enabled optimization by the manipulation of genetic materials associated with biological control agents. Two significant advancements are the discovery of cytoplasmic incompatibility induced by Wolbachia bacteria, which has enhanced replacement programs, and the introduction of dominant lethal genes into local mosquito populations through the release of genetically modified mosquitoes. As various arboviruses continue to be significant public health threats, biological control strategies have evolved to be more diverse and become critical tools to reduce the disease burden of arboviruses.

The emerging threat of domestic terrorism: a systematic review of evolving needs, threats, and opportunities

OpenAIRE

Wright, Lynn M.

2014-01-01

Approved for public release; distribution is unlimited The domestic terrorist threat in the United States is active and complex, with ongoing threats from violent left- and right-wing extremist groups, and radicalization and recruitment efforts by international terrorist groups. In response, domestic intelligence agencies, at all levels of government, have instituted reforms and improvements since 9/11, but there are still gaps in information-sharing and community engagement. For example, ...

Strengths Weaknesses Opportunities and Threats of Blended Learning: Students’ Perceptions

Science.gov (United States)

Hande, S

2014-01-01

Background: Blended learning (BL) in a cell biology course of the premedical program at the Kasturba Medical College International Centre, Manipal, India, commenced in 2006. The program provides training in basic sciences to students, especially from the United States and Canada. The approach to the study was phenomenographic, with a qualitative study design using an open-ended questionnaire, focused interviews and empirical observations. Aim: The aim of this study was to identify the strengths, weaknesses, opportunities and threats (SWOT) of BL in a premedical class. Subjects and Methods: It was a cross-sectional study. Ninety six students in a premedical cell biology class participated in the study. SWOT analysis of students’ perceptions was conducted manually. Statistical analysis included content analysis of qualitative data to classify data and aligning them into the SWOT analysis matrix. Results: The outcomes of the study revealed student perceptions in terms of SWOT of BL and the potential uses of this strategy. Conclusions: The study provides background for educators and curriculum experts to plan their modules while incorporating a BL approach. PMID:24971204

Strengths weaknesses opportunities and threats of blended learning: students' perceptions.

Science.gov (United States)

Hande, S

2014-05-01

Blended learning (BL) in a cell biology course of the premedical program at the Kasturba Medical College International Centre, Manipal, India, commenced in 2006. The program provides training in basic sciences to students, especially from the United States and Canada. The approach to the study was phenomenographic, with a qualitative study design using an open-ended questionnaire, focused interviews and empirical observations. The aim of this study was to identify the strengths, weaknesses, opportunities and threats (SWOT) of BL in a premedical class. It was a cross-sectional study. Ninety six students in a premedical cell biology class participated in the study. SWOT analysis of students' perceptions was conducted manually. Statistical analysis included content analysis of qualitative data to classify data and aligning them into the SWOT analysis matrix. The outcomes of the study revealed student perceptions in terms of SWOT of BL and the potential uses of this strategy. The study provides background for educators and curriculum experts to plan their modules while incorporating a BL approach.

Digital Threat and Vulnerability Management: The SVIDT Method

Directory of Open Access Journals (Sweden)

Roland W. Scholz

2017-04-01

Full Text Available The Digital Revolution is inducing major threats to many types of human systems. We present the SVIDT method (a Strengths, Vulnerability, and Intervention Assessment related to Digital Threats for managing the vulnerabilities of human systems with respect to digital threats and changes. The method first performs a multilevel system–actor analysis for assessing vulnerabilities and strengths with respect to digital threats. Then, the method identifies threat scenarios that may become real. By constructing, evaluating, and launching interventions against all identified digital threats and their critical negative outcomes, the resilience of a specific human system can be improved. The evaluation of interventions is done when strengthening the adaptive capacity, i.e., a system’s capability to cope with negative outcomes that may take place in the future. The SVIDT method is embedded in the framework of coupled human–environment systems, the theory of risk and vulnerability assessment, types of adaptation (assimilation vs. accommodation, and a comprehensive sustainability evaluation. The SVIDT method is exemplarily applied to an enterprise (i.e., a Swiss casino for which online gaming has become an essential digital-business field. The discussion reflects on the specifics of digital threats and discusses both the potential benefits and limitations of the SVIDT method.

Conservatism and the neural circuitry of threat: economic conservatism predicts greater amygdala-BNST connectivity during periods of threat vs safety.

Science.gov (United States)

Pedersen, Walker S; Muftuler, L Tugan; Larson, Christine L

2018-01-01

Political conservatism is associated with an increased negativity bias, including increased attention and reactivity toward negative and threatening stimuli. Although the human amygdala has been implicated in the response to threatening stimuli, no studies to date have investigated whether conservatism is associated with altered amygdala function toward threat. Furthermore, although an influential theory posits that connectivity between the amygdala and bed nucleus of the stria terminalis (BNST) is important in initiating the response to sustained or uncertain threat, whether individual differences in conservatism modulate this connectivity is unknown. To test whether conservatism is associated with increased reactivity in neural threat circuitry, we measured participants' self-reported social and economic conservatism and asked them to complete high-resolution fMRI scans while under threat of an unpredictable shock and while safe. We found that economic conservatism predicted greater connectivity between the BNST and a cluster of voxels in the left amygdala during threat vs safety. These results suggest that increased amygdala-BNST connectivity during threat may be a key neural correlate of the enhanced negativity bias found in conservatism. © The Author (2017). Published by Oxford University Press.

THE BIOTERRORISM THREAT: TECHNOLOGICAL AND POLITICAL CONSIDERATIONS

Energy Technology Data Exchange (ETDEWEB)

J. F. PILAT

2000-03-01

Bioterrorism--along with biowarfare, from which it may not always be distinguishable in practice--will be a feature of the strategic landscape in the 21st century and is high on the US national security agenda. Bioterrorism poses a potential threat to the US population, agriculture, interests, friends and allies, and military forces (asymmetric threats). Yet these possibilities have not been widely pursued or realized by terrorists. The perceived threat is far worse than anything experienced to date, and is largely technologically driven.

Theory of Prejudice and American Identity Threat Transfer for Latino and Asian Americans.

Science.gov (United States)

Sanchez, Diana T; Chaney, Kimberly E; Manuel, Sara K; Remedios, Jessica D

2018-03-01

Latinos and Asian Americans confront similar stereotypes as they are often presumed to be foreigners and subjected to American identity denial. Across six studies (total N = 992), we demonstrate that Latinos and Asians anticipate ingroup prejudice and specific types of subordination (e.g., American identity threat) in the face of outgroup threats that target one another (i.e., stigma transfer). The studies explore whether stigma transfer occurred primarily when shared Latino and Asian stereotype content was a salient component of the prejudice remark (e.g., foreigner stereotypes; Study 3), or when outgroup prejudice targeted a social group with shared stereotype content (Study 4), though neither appeared to substantively moderate stigma transfer. Minority group members who conceptualize prejudiced people as holding multiple biases (i.e., a monolithic prejudice theory) were more susceptible to stigma transfer suggesting that stereotype content is not necessary for stigma transfer because people assume that prejudice is not singular.

Affirmative Action and Stereotype Threat

OpenAIRE

Cohen, Alma

2015-01-01

This paper provides experimental evidence on the effect of affirmative action (AA). In particular, we investigate whether affirmative action has a ”stereotype threat effect” – that is, whether AA cues a negative stereotype that leads individuals to conform to the stereotype and adversely affects their performance. Stereotype threat has been shown in the literature to be potentially significant for individuals who identify strongly with the domain of the stereotype and who engage in complex st...

Stereotype Threat Alters the Subjective Experience of Memory.

Science.gov (United States)

Mazerolle, Marie; Régner, Isabelle; Rigalleau, François; Huguet, Pascal

2015-01-01

There is now evidence that negative age-related stereotypes about memory reduce older adults' memory performance, and inflate age differences in this domain. Here, we examine whether stereotype threat may also influence the basic feeling that one is more or less able to remember. Using the Remember/Know paradigm, we demonstrated that stereotype threat conducted older adults to a greater feeling of familiarity with events, while failing to retrieve any contextual detail. This finding indicates that stereotype threat alters older adults' subjective experience of memory, and strengthens our understanding of the mechanisms underlying stereotype threat effects.

An evaluation of security measures implemented to address physical threats to water infrastructure in the state of Mississippi.

Science.gov (United States)

Barrett, Jason R; French, P Edward

2013-01-01

The events of September 11, 2001, increased and intensified domestic preparedness efforts in the United States against terrorism and other threats. The heightened focus on protecting this nation's critical infrastructure included legislation requiring implementation of extensive new security measures to better defend water supply systems against physical, chemical/biological, and cyber attacks. In response, municipal officials have implemented numerous safeguards to reduce the vulnerability of these systems to purposeful intrusions including ongoing vulnerability assessments, extensive personnel training, and highly detailed emergency response and communication plans. This study evaluates fiscal year 2010 annual compliance assessments of public water systems with security measures that were implemented by Mississippi's Department of Health as a response to federal requirements to address these potential terrorist threats to water distribution systems. The results show that 20 percent of the water systems in this state had at least one security violation on their 2010 Capacity Development Assessment, and continued perseverance from local governments is needed to enhance the resiliency and robustness of these systems against physical threats.

Software authority transition through multiple distributors.

Science.gov (United States)

Han, Kyusunk; Shon, Taeshik

2014-01-01

The rapid growth in the use of smartphones and tablets has changed the software distribution ecosystem. The trend today is to purchase software through application stores rather than from traditional offline markets. Smartphone and tablet users can install applications easily by purchasing from the online store deployed in their device. Several systems, such as Android or PC-based OS units, allow users to install software from multiple sources. Such openness, however, can promote serious threats, including malware and illegal usage. In order to prevent such threats, several stores use online authentication techniques. These methods can, however, also present a problem whereby even licensed users cannot use their purchased application. In this paper, we discuss these issues and provide an authentication method that will make purchased applications available to the registered user at all times.

Quantifying the threat of extinction from Muller's ratchet in the diploid Amazon molly (Poecilia formosa

Directory of Open Access Journals (Sweden)

Loewe Laurence

2008-03-01

Full Text Available Abstract Background The Amazon molly (Poecilia formosa is a small unisexual fish that has been suspected of being threatened by extinction from the stochastic accumulation of slightly deleterious mutations that is caused by Muller's ratchet in non-recombining populations. However, no detailed quantification of the extent of this threat is available. Results Here we quantify genomic decay in this fish by using a simple model of Muller's ratchet with the most realistic parameter combinations available employing the evolution@home global computing system. We also describe simple extensions of the standard model of Muller's ratchet that allow us to deal with selfing diploids, triploids and mitotic recombination. We show that Muller's ratchet creates a threat of extinction for the Amazon molly for many biologically realistic parameter combinations. In most cases, extinction is expected to occur within a time frame that is less than previous estimates of the age of the species, leading to a genomic decay paradox. Conclusion How then does the Amazon molly survive? Several biological processes could individually or in combination solve this genomic decay paradox, including paternal leakage of undamaged DNA from sexual sister species, compensatory mutations and many others. More research is needed to quantify the contribution of these potential solutions towards the survival of the Amazon molly and other (ancient asexual species.

Don’t bust the biological soil crust: Preserving and restoring an important desert resource

Science.gov (United States)

Sue Miller; Steve Warren; Larry St. Clair

2017-01-01

Biological soil crusts are a complex of microscopic organisms growing on the soil surface in many arid and semi-arid ecosystems. These crusts perform the important role of stabilizing soil and reducing or eliminating water and wind erosion. One of the largest threats to biological soil crusts in the arid and semi-arid areas of the western United States is mechanical...

Eastern forest environmental threat assessment center

Science.gov (United States)

Southern Research Station. USDA Forest Service

2010-01-01

The Eastern Forest Environmental Threat Assessment Center (EFETAC) provides the latest research and expertise concerning threats to healthy forests – such as insects and disease, wildland loss, invasive species, wildland fire, and climate change – to assist forest landowners, managers and scientists throughout the East. Established in 2005, EFETAC is a joint effort of...

Bomb Threats and Bomb Search Techniques.

Science.gov (United States)

Department of the Treasury, Washington, DC.

This pamphlet explains how to be prepared and plan for bomb threats and describes procedures to follow once a call has been received. The content covers (1) preparation for bomb threats, (2) evacuation procedures, (3) room search methods, (4) procedures to follow once a bomb has been located, and (5) typical problems that search teams will…

Complex biological and bio-inspired systems

Energy Technology Data Exchange (ETDEWEB)

Ecke, Robert E [Los Alamos National Laboratory

2009-01-01

The understanding and characterization ofthe fundamental processes of the function of biological systems underpins many of the important challenges facing American society, from the pathology of infectious disease and the efficacy ofvaccines, to the development of materials that mimic biological functionality and deliver exceptional and novel structural and dynamic properties. These problems are fundamentally complex, involving many interacting components and poorly understood bio-chemical kinetics. We use the basic science of statistical physics, kinetic theory, cellular bio-chemistry, soft-matter physics, and information science to develop cell level models and explore the use ofbiomimetic materials. This project seeks to determine how cell level processes, such as response to mechanical stresses, chemical constituents and related gradients, and other cell signaling mechanisms, integrate and combine to create a functioning organism. The research focuses on the basic physical processes that take place at different levels ofthe biological organism: the basic role of molecular and chemical interactions are investigated, the dynamics of the DNA-molecule and its phylogenetic role are examined and the regulatory networks of complex biochemical processes are modeled. These efforts may lead to early warning algorithms ofpathogen outbreaks, new bio-sensors to detect hazards from pathomic viruses to chemical contaminants. Other potential applications include the development of efficient bio-fuel alternative-energy processes and the exploration ofnovel materials for energy usages. Finally, we use the notion of 'coarse-graining,' which is a method for averaging over less important degrees of freedom to develop computational models to predict cell function and systems-level response to disease, chemical stress, or biological pathomic agents. This project supports Energy Security, Threat Reduction, and the missions of the DOE Office of Science through its efforts to

Self-Construal Priming Modulates Self-Evaluation under Social Threat

Directory of Open Access Journals (Sweden)

Tianyang Zhang

2017-10-01

Full Text Available Previous studies have shown that Westerners evaluate themselves in an especially flattering way when faced with a social-evaluative threat. The current study first investigated whether East Asians also have a similar pattern by recruiting Chinese participants and using social-evaluative threat manipulations in which participants perform self-evaluation tasks while adopting different social-evaluative feedbacks (Experiment 1. Then further examined whether the different response patterns can be modulated by different types of self-construal by using social-evaluative threat manipulations in conjunction with a self-construal priming task (Experiment 2. The results showed that, as opposed to Westerners' pattern, Chinese participants rated themselves as having significantly greater above-average effect only when faced with the nonthreatening feedback but not the social-evaluative threat. More importantly, we found that self-construal modulated the self-evaluation under social-evaluative threat: following independent self-construal priming, participants tended to show a greater above-average effect when faced with a social-evaluative threat. However, this pattern in conjunction with a social threat disappeared after participants received interdependent self-construal priming or neutral priming. These findings suggest that the effects of social-evaluative threat on self-evaluation are not culturally universal and is strongly modulated by self-construal priming.

School Shooting : Threat Detection and Classification in Textual Leakage

OpenAIRE

Khan, Ajmal

2013-01-01

The continual occurrence of school shooting incidents underscores the need of taking preventive measures. Inductive measures of threat assessment have proved to be a bad strategy to solve the problem and new research is focusing on deductive approaches. Deductive threat assessment approaches are gaining ground and efforts are underway to mine text for automatic detection of threats in written text. Automatic detection and classification of threats in the digital world can help the decision ma...

Synthetic Biology: Putting Synthesis into Biology

Science.gov (United States)

Liang, Jing; Luo, Yunzi; Zhao, Huimin

2010-01-01

The ability to manipulate living organisms is at the heart of a range of emerging technologies that serve to address important and current problems in environment, energy, and health. However, with all its complexity and interconnectivity, biology has for many years been recalcitrant to engineering manipulations. The recent advances in synthesis, analysis, and modeling methods have finally provided the tools necessary to manipulate living systems in meaningful ways, and have led to the coining of a field named synthetic biology. The scope of synthetic biology is as complicated as life itself – encompassing many branches of science, and across many scales of application. New DNA synthesis and assembly techniques have made routine the customization of very large DNA molecules. This in turn has allowed the incorporation of multiple genes and pathways. By coupling these with techniques that allow for the modeling and design of protein functions, scientists have now gained the tools to create completely novel biological machineries. Even the ultimate biological machinery – a self-replicating organism – is being pursued at this moment. It is the purpose of this review to dissect and organize these various components of synthetic biology into a coherent picture. PMID:21064036

Biological Control Strategies for Mosquito Vectors of Arboviruses

Directory of Open Access Journals (Sweden)

Yan-Jang S. Huang

2017-02-01

Full Text Available Historically, biological control utilizes predatory species and pathogenic microorganisms to reduce the population of mosquitoes as disease vectors. This is particularly important for the control of mosquito-borne arboviruses, which normally do not have specific antiviral therapies available. Although development of resistance is likely, the advantages of biological control are that the resources used are typically biodegradable and ecologically friendly. Over the past decade, the advancement of molecular biology has enabled optimization by the manipulation of genetic materials associated with biological control agents. Two significant advancements are the discovery of cytoplasmic incompatibility induced by Wolbachia bacteria, which has enhanced replacement programs, and the introduction of dominant lethal genes into local mosquito populations through the release of genetically modified mosquitoes. As various arboviruses continue to be significant public health threats, biological control strategies have evolved to be more diverse and become critical tools to reduce the disease burden of arboviruses.

Improving buried threat detection in ground-penetrating radar with transfer learning and metadata analysis

Science.gov (United States)

Colwell, Kenneth A.; Torrione, Peter A.; Morton, Kenneth D.; Collins, Leslie M.

2015-05-01

Ground-penetrating radar (GPR) technology has proven capable of detecting buried threats. The system relies on a binary classifier that is trained to distinguish between two classes: a target class, encompassing many types of buried threats and their components; and a nontarget class, which includes false alarms from the system prescreener. Typically, the training process involves a simple partition of the data into these two classes, which allows for straightforward application of standard classifiers. However, since training data is generally collected in fully controlled environments, it includes auxiliary information about each example, such as the specific type of threat, its purpose, its components, and its depth. Examples from the same specific or general type may be expected to exhibit similarities in their GPR data, whereas examples from different types may differ greatly. This research aims to leverage this additional information to improve overall classification performance by fusing classifier concepts for multiple groups, and to investigate whether structure in this information can be further utilized for transfer learning, such that the amount of expensive training data necessary to learn a new, previously-unseen target type may be reduced. Methods for accomplishing these goals are presented with results from a dataset containing a variety of target types.

Modeling and simulation of botnet based cyber-threats

Directory of Open Access Journals (Sweden)

Kasprzyk Rafał

2017-01-01

Full Text Available The paper presents an analysis of cyber-threats, with particular emphasis on the threats resulting from botnet activity. Botnets are the most common types of threats and often perceived as crucial in terms of national security. Their classification and methods of spreading are the basis for creating cyberspace model including the presence of different types of cyber-threats. A well-designed cyberspace model enables to construct an experimental environment that allows for the analysis of botnet characteristics, testing its resistance to various events and simulation of the spread and evolution. For this purpose, dedicated platforms with capabilities and functional characteristics to meet these requirements have been proposed.

Distance Measurement Methods for Improved Insider Threat Detection

Directory of Open Access Journals (Sweden)

Owen Lo

2018-01-01

Full Text Available Insider threats are a considerable problem within cyber security and it is often difficult to detect these threats using signature detection. Increasing machine learning can provide a solution, but these methods often fail to take into account changes of behaviour of users. This work builds on a published method of detecting insider threats and applies Hidden Markov method on a CERT data set (CERT r4.2 and analyses a number of distance vector methods (Damerau–Levenshtein Distance, Cosine Distance, and Jaccard Distance in order to detect changes of behaviour, which are shown to have success in determining different insider threats.

The opportunity-threat theory of decision-making under risk

OpenAIRE

Mohan Pandey

2018-01-01

A new theory of decision-making under risk, the Opportunity-Threat Theory is proposed. Analysis of risk into opportunity and threat components allows description of behavior as a combination of opportunity seeking and threat aversion. Expected utility is a special case of this model. The final evaluation is an integration of the impacts of opportunity and threat with this expectation. The model can account for basic results as well as several ``new paradoxes'' that refuted c...

Bioterrorism and Biological Warfare, from Past to the Present: A classic review

Directory of Open Access Journals (Sweden)

Majid Zare Bidaki

2015-10-01

Full Text Available Bioterrorism is defined as any terrorist action of intentional release or dissemination of highly pathogenic biological agents, including a variety of microorganisms or biological toxins. With the growing threat of terrorism, is necessary that the potential danger of various microorganisms – as a powerful tool of aggression and threat- to be taken seriously. This review tries to explain the concept of biological weapons and their historical development process with an emphasis on efforts to control the proliferation of these types of weapons over the last century. Potential impact of infectious diseases on people and armed forces was known from since 600 BC. Using the victims of the plague as a weapon in medieval warfare and spread of smallpox as a weapon during the war against the Indians when initially America was discovered, the development of biological weapons during the World War I, World War II and the Cold War, and even since the beginning of the third millennium, all show the strategic importance of pathogenic microorganisms as a deterrent power for the superiority of some governments and cults. Historical attempts to use infectious diseases as biological weapons reveal that the distinction between a natural outbreak of an infectious disease and that of a deliberate biological attack is very difficult. Abusing this characteristic of infectious diseases has made it possible for the purposes of superiority. International agreements to control the development of biological weapons, such as “the 1925 Geneva Protocol” and “the Convention on the Prohibition of the Development, Production and Stockpiling of Biological and Toxic Weapons” have not been able to control the development and using of biological warfare.  The current paper is a classic review (Overview article aiming at increasing the knowledge and awareness of people especially of health authorities and government officials.

Biological couplings: Classification and characteristic rules

Institute of Scientific and Technical Information of China (English)

无

2009-01-01

The phenomena that biological functions originate from biological coupling are the important biological foundation of multiple bionics and the significant discoveries in the bionic fields. In this paper, the basic concepts related to biological coupling are introduced from the bionic viewpoint. Constitution, classification and characteristic rules of biological coupling are illuminated, the general modes of biological coupling studies are analyzed, and the prospects of multi-coupling bionics are predicted.

Research on classification of nuclear and radiological accident from IAEA threat category with estimation of INES scale

International Nuclear Information System (INIS)

Cha, Seok Ki; Kim, Siu

2017-01-01

As there is increasing use of nuclear energy and radiation while information on nuclear related accidents are accumulated, international interest in nuclear and radiation incidents is increasing rapidly. Because of the specificity of nuclear energy and radiation, the damage caused by such accidents will be spread to the larger area around the accident point due to the radiation and cause biological damage and mental-psychological damage. The purpose of this study is to categorize historical incidents using the Threat Category concept described in the publication of IAEA Safety Guide GS-G-2.1. In addition to categorizing actual events and accidents into Threat Categories, causes of occurrences, the type of radioactive source which leads to the main threats, the type of radiation exposure, and the type of patient are organized in detail. As a result of the analysis of representative historical cases, most accident cases caused by 'Nuclear Energy-Related Business Operator' correspond to 1 (Anomaly) ~ 4 (Accident with Local Consequences) in the INES Scale by IAEA. From the some accident cases, while the radiological damage can be seen to be local, but it can be seen that the possibility of 6 (Serious Accident) can not be absolutely excluded.

Applying the multi-threat framework of stereotype threat in the context of digital gaming.

Science.gov (United States)

Pennington, Charlotte R; Kaye, Linda K; McCann, Joseph J

2018-01-01

Females often report experiencing stigmatisation pertaining to their competency in digital gaming communities. Employing the principles of the multi-threat framework of stereotype threat, the current research examined the impact of gender-related stereotypes on females' gaming performance and related self-perceptions. In Experiment 1, 90 females were assigned to one of three conditions in which they were primed that their performance would be either diagnostic of their personal (self-as-target) or gender group's ability (group-as-target) or would be non-diagnostic of gaming ability (control). In Experiment 2, 90 females were primed that their performance would be judged by a group of other females (in-group source) or males (out-group source), or would be non-diagnostic of ability (control). Participants then completed a casual gaming task, as well as measures of competence beliefs, self-efficacy and self-esteem. Findings from Experiment 1 indicate that neither a self-as-target nor a group-as-target stereotype affected significantly gaming performance, or game-related self-efficacy, self-esteem and competency beliefs. Findings from Experiment 2 reveal further that females' gaming performance and associated self-perceptions were not impacted significantly by an in-group or out-group source of stereotype threat. The discussion turns to potential explanations for these findings, proposing that females may not perceive negative gender-gaming stereotypes to be an accurate representation of their personal or social group's gaming ability. We also discuss the implications of the experimental design and difficulty, as well as the potential for domain identification to moderate performance outcomes under stereotype threat.

Applying the multi-threat framework of stereotype threat in the context of digital gaming.

Directory of Open Access Journals (Sweden)

Charlotte R Pennington

Full Text Available Females often report experiencing stigmatisation pertaining to their competency in digital gaming communities. Employing the principles of the multi-threat framework of stereotype threat, the current research examined the impact of gender-related stereotypes on females' gaming performance and related self-perceptions. In Experiment 1, 90 females were assigned to one of three conditions in which they were primed that their performance would be either diagnostic of their personal (self-as-target or gender group's ability (group-as-target or would be non-diagnostic of gaming ability (control. In Experiment 2, 90 females were primed that their performance would be judged by a group of other females (in-group source or males (out-group source, or would be non-diagnostic of ability (control. Participants then completed a casual gaming task, as well as measures of competence beliefs, self-efficacy and self-esteem. Findings from Experiment 1 indicate that neither a self-as-target nor a group-as-target stereotype affected significantly gaming performance, or game-related self-efficacy, self-esteem and competency beliefs. Findings from Experiment 2 reveal further that females' gaming performance and associated self-perceptions were not impacted significantly by an in-group or out-group source of stereotype threat. The discussion turns to potential explanations for these findings, proposing that females may not perceive negative gender-gaming stereotypes to be an accurate representation of their personal or social group's gaming ability. We also discuss the implications of the experimental design and difficulty, as well as the potential for domain identification to moderate performance outcomes under stereotype threat.

Stereotype threat in salary negotiations is mediated by reservation salary.

Science.gov (United States)

Tellhed, Una; Björklund, Fredrik

2011-04-01

Women are stereotypically perceived as worse negotiators than men, which may make them ask for less salary than men when under stereotype threat (Kray et al., 2001). However, the mechanisms of stereotype threat are not yet properly understood. The current study investigated whether stereotype threat effects in salary negotiations can be explained by motivational factors. A total of 116 business students negotiated salary with a confederate and were either told that this was diagnostic of negotiating ability (threat manipulation) or not. Measures of minimum (reservation) and ideal (aspiration) salary goals and regulatory focus were collected. The finding (Kray et al., 2001) that women make lower salary requests than men when under stereotype threat was replicated. Women in the threat condition further reported lower aspiration salary, marginally significantly lower reservation salary and less eagerness/more vigilance than men. Reservation salary mediated the stereotype threat effect, and there was a trend for regulatory focus to mediate the effect. Thus, reservation salary partly explains why women ask for less salary than men under stereotype threat. Female negotiators may benefit from learning that stereotype threat causes sex-differences in motivation. © 2010 The Authors. Scandinavian Journal of Psychology © 2010 The Scandinavian Psychological Associations.

Insider threat to secure facilities: data analysis

International Nuclear Information System (INIS)

1980-01-01

Three data sets drawn from industries that have experienced internal security breaches are analyzed. The industries and the insider security breaches are considered analogous in one or more respects to insider threats potentially confronting managers in the nuclear industry. The three data sets are: bank fraud and embezzlement (BF and E), computer-related crime, and drug theft from drug manufacturers and distributors. A careful analysis by both descriptive and formal statistical techniques permits certain general conclusions on the internal threat to secure industries to be drawn. These conclusions are discussed and related to the potential insider threat in the nuclear industry. 49 tabs

A combined emitter threat assessment method based on ICW-RCM

Science.gov (United States)

Zhang, Ying; Wang, Hongwei; Guo, Xiaotao; Wang, Yubing

2017-08-01

Considering that the tradition al emitter threat assessment methods are difficult to intuitively reflect the degree of target threaten and the deficiency of real-time and complexity, on the basis of radar chart method(RCM), an algorithm of emitter combined threat assessment based on ICW-RCM (improved combination weighting method, ICW) is proposed. The coarse sorting is integrated with fine sorting in emitter combined threat assessment, sequencing the emitter threat level roughly accordance to radar operation mode, and reducing task priority of the low-threat emitter; On the basis of ICW-RCM, sequencing the same radar operation mode emitter roughly, finally, obtain the results of emitter threat assessment through coarse and fine sorting. Simulation analyses show the correctness and effectiveness of this algorithm. Comparing with classical method of emitter threat assessment based on CW-RCM, the algorithm is visual in image and can work quickly with lower complexity.

A Biological Security Motivation System for Potential Threats: Are There Implications for Policy-Making?

Directory of Open Access Journals (Sweden)

Erik Z Woody

2013-09-01

Full Text Available Research indicates that there is a specially adapted, hard-wired brain circuit, the security motivation system, which evolved to manage potential threats, such as the possibility of contamination or predation. The existence of this system may have important implications for policy-making related to security. The system is sensitive to partial, uncertain cues of potential danger, detection of which activates a persistent, potent motivational state of wariness or anxiety. This state motivates behaviours to probe the potential danger, such as checking, and to correct for it, such as washing. Engagement in these behaviours serves as the terminating feedback for the activation of the system. Because security motivation theory makes predictions about what kinds of stimuli activate security motivation and what conditions terminate it, the theory may have applications both in understanding how policy-makers can best influence others, such as the public, and also in understanding the behavior of policy-makers themselves.

ChemProt: a disease chemical biology database

DEFF Research Database (Denmark)

Taboureau, Olivier; Nielsen, Sonny Kim; Audouze, Karine Marie Laure

2011-01-01

Systems pharmacology is an emergent area that studies drug action across multiple scales of complexity, from molecular and cellular to tissue and organism levels. There is a critical need to develop network-based approaches to integrate the growing body of chemical biology knowledge with network...... biology. Here, we report ChemProt, a disease chemical biology database, which is based on a compilation of multiple chemical-protein annotation resources, as well as disease-associated protein-protein interactions (PPIs). We assembled more than 700 000 unique chemicals with biological annotation for 30...... evaluation of environmental chemicals, natural products and approved drugs, as well as the selection of new compounds based on their activity profile against most known biological targets, including those related to adverse drug events. Results from the disease chemical biology database associate citalopram...

Left-Wing Extremism: The Current Threat

Energy Technology Data Exchange (ETDEWEB)

Karl A. Seger

2001-04-30

Left-wing extremism is ''alive and well'' both in the US and internationally. Although the current domestic terrorist threat within the U. S. is focused on right-wing extremists, left-wing extremists are also active and have several objectives. Leftist extremists also pose an espionage threat to U.S. interests. While the threat to the U.S. government from leftist extremists has decreased in the past decade, it has not disappeared. There are individuals and organizations within the U.S. who maintain the same ideology that resulted in the growth of left-wing terrorism in this country in the 1970s and 1980s. Some of the leaders from that era are still communicating from Cuba with their followers in the U.S., and new leaders and groups are emerging.

Emerging and Future Cyber Threats to Critical Systems

OpenAIRE

Djambazova , Edita; Almgren , Magnus; Dimitrov , Kiril; Jonsson , Erland

2010-01-01

Part 2: Adversaries; International audience; This paper discusses the emerging and future cyber threats to critical systems identified during the EU/FP7 project ICT-FORWARD. Threats were identified after extensive discussions with both domain experts and IT security professionals from academia, industry, and government organizations. The ultimate goal of the work was to identify the areas in which cyber threats could occur and cause serious and undesirable consequences, based on the character...

Software Authority Transition through Multiple Distributors

Directory of Open Access Journals (Sweden)

Kyusunk Han

2014-01-01

Full Text Available The rapid growth in the use of smartphones and tablets has changed the software distribution ecosystem. The trend today is to purchase software through application stores rather than from traditional offline markets. Smartphone and tablet users can install applications easily by purchasing from the online store deployed in their device. Several systems, such as Android or PC-based OS units, allow users to install software from multiple sources. Such openness, however, can promote serious threats, including malware and illegal usage. In order to prevent such threats, several stores use online authentication techniques. These methods can, however, also present a problem whereby even licensed users cannot use their purchased application. In this paper, we discuss these issues and provide an authentication method that will make purchased applications available to the registered user at all times.

Sensors and actuators inherent in biological species

Science.gov (United States)

Taya, Minoru; Stahlberg, Rainer; Li, Fanghong; Zhao, Ying Joyce

2007-04-01

This paper addresses examples of sensing and active mechanisms inherent in some biological species where both plants and animals cases are discussed: mechanosensors and actuators in Venus Fly Trap and cucumber tendrils, chemosensors in insects, two cases of interactions between different kingdoms, (i) cotton plant smart defense system and (ii) bird-of-paradise flower and hamming bird interaction. All these cases lead us to recognize how energy-efficient and flexible the biological sensors and actuators are. This review reveals the importance of integration of sensing and actuation functions into an autonomous system if we make biomimetic design of a set of new autonomous systems which can sense and actuate under a number of different stimuli and threats.

Confronting challenges to economic analysis of biological invasions in forests

Science.gov (United States)

Thomas P Holmes

2010-01-01

Biological invasions of forests by non-indigenous organisms present a complex, persistent, and largely irreversible threat to forest ecosystems around the globe. Rigorous assessments of the economic impacts of introduced species, at a national scale, are needed to provide credible information to policy makers. It is proposed here that microeconomic models of damage due...

Game Theoretic Risk Analysis of Security Threats

CERN Document Server

Bier, Vicki M

2008-01-01

Introduces reliability and risk analysis in the face of threats by intelligent agents. This book covers applications to networks, including problems in both telecommunications and transportation. It provides a set of tools for applying game theory TO reliability problems in the presence of intentional, intelligent threats

Advanced Insider Threat Mitigation Workshop Instructional Materials

Energy Technology Data Exchange (ETDEWEB)

Gibbs, Philip [Brookhaven National Lab. (BNL), Upton, NY (United States); Larsen, Robert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); O' Brien, Mike [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Edmunds, Tom [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2009-02-01

Insiders represent a formidable threat to nuclear facilities. This set of workshop materials covers methodologies to analyze and approaches to mitigate the threat of an insider attempting abrupt and protracted theft of nuclear materials. This particular set of materials is an update of a January 2008 version to add increased emphasis on Material Control and Accounting and its role with respect to protracted insider nuclear material theft scenarios. This report is a compilation of workshop materials consisting of lectures on technical and administrative measures used in Physical Protection (PP) and Material Control and Accounting (MC&A) and methods for analyzing their effectiveness against a postulated insider threat. The postulated threat includes both abrupt and protracted theft scenarios. Presentation is envisioned to be through classroom instruction and discussion. Several practical and group exercises are included for demonstration and application of the analysis approach contained in the lecture/discussion sessions as applied to a hypothetical nuclear facility.

Implicit self-esteem compensation: automatic threat defense.

Science.gov (United States)

Rudman, Laurie A; Dohn, Matthew C; Fairchild, Kimberly

2007-11-01

Four experiments demonstrated implicit self-esteem compensation (ISEC) in response to threats involving gender identity (Experiment 1), implicit racism (Experiment 2), and social rejection (Experiments 3-4). Under conditions in which people might be expected to suffer a blow to self-worth, they instead showed high scores on 2 implicit self-esteem measures. There was no comparable effect on explicit self-esteem. However, ISEC was eliminated following self-affirmation (Experiment 3). Furthermore, threat manipulations increased automatic intergroup bias, but ISEC mediated these relationships (Experiments 2-3). Thus, a process that serves as damage control for the self may have negative social consequences. Finally, pretest anxiety mediated the relationship between threat and ISEC (Experiment 3), whereas ISEC negatively predicted anxiety among high-threat participants (Experiment 4), suggesting that ISEC may function to regulate anxiety. The implications of these findings for automatic emotion regulation, intergroup bias, and implicit self-esteem measures are discussed. (c) 2007 APA, all rights reserved.

The journal of medical chemical, biological and radiological defense, an update

International Nuclear Information System (INIS)

Price, B. B. S.; Peitersen, L.E.

2009-01-01

The Journal of Medical Chemical, Biological, and Radiological Defense (www.JMedCBR.org) is a peer-reviewed scientific online journal focusing on the biology, chemistry, physiology, toxicology and treatment of exposure to threat agents. JMedCBR provides a central international forum for the publication of current research and development information on medical chemical, biological and radiological defense, as well as training, doctrine, and problems related to chemical, biological and radiological casualties. JMedCBR is sponsored by the US Defense Threat Reduction Agency (DTRA) Chem-Bio Technologies Directorate as part of its scientific outreach program in chemical and biological defense solutions for the Department of Defense. In addition to scientific and medical research, JMedCBR hosts an archive of related papers from authors in the field. Although organized into annual issues, articles are published on the web continuously. The complete JMedCBR is published electronically and is made available to the scientific community free of charge. JMedCBR is committed to providing its readers with quality scientific information and critical analyses. All submissions are peer-reviewed by an editorial board of recognized and respected international scientists who represent expertise in different aspects of medical chemical, biological and radiological defense. Contributions to JMedCBR must be original works of the author(s) and must not have been previously published or simultaneously submitted to other publications. The author(s) transfer the copyright of articles published in JMedCBR to the journal. A copyright transfer form must accompany each manuscript submission. For more information on submitting to JMedCBR, see the Authors' Guide, available at http://www.jmedcbr.org/authorGuide.html.(author)

Interim Consequence Management Guidance for a Wide-Area Biological Attack

Energy Technology Data Exchange (ETDEWEB)

Raber, Ellen [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kirvel, Robert [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); MacQueen, Don [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Love, Adam [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Dombroski, Matthew [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); McGrann, Thomas [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Richards, John [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Melius, Carl [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bunt, Thomas [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hibbard, Wilthea [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Greenwalt, Robert [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Miles, Robin [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Dillon, Michael [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Mancieri, Sav [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Harris, Steve [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Michalik, Richard [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wheeler, Richard [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hoppes, Bill [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Tucker, Mark [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Krauter, Paula [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Knowlton, Robert [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Yang, Lynn [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Franco, Dave [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Einfeld, Wayne [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Brockman, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Betty, Rita [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2011-05-17

The Interagency Biological Restoration Demonstration (IBRD) program is a collaborative, interagency effort co-chaired by the Department of Homeland Security and Department of Defense aimed at improving the nation‘s ability to respond to and recover from a large-scale, wide-area, domestic attack involving the release of an environmentally persistent biological warfare agent. The program is focused on understanding interactions between the civilian and military sectors, and in building mutual support to carry out such remediations. This Interim Consequence Management Guidance document provides guidance for decisionmakers in executing activities required to respond to and recover from a biological incident affecting a wide urban area insofar as information is currently available. The spore-forming bacterium Bacillus anthracis is discussed as the biological agent of primary concern because it is the most difficult of known bioterrorism agents to inactivate and is considered to be one of the key threat agents. Most other biological threat agents are much easier to remediate, and in many cases, inactivation would occur naturally within days as a result of environmental exposure; however, the framework and operational questions that need to be addressed are expected to remain the same. The guidance in this document is applicable to (1) enclosed facilities, such as commercial, residential, and continental U.S. military facilities; (2) semi-enclosed facilities, such as subways and public transit facilities; (3) outdoor areas (both localized and wide area), such as building exteriors, streets, parks, and other open spaces; (4) drinking water facilities; and (5) drinking water sources. This document follows an interagency framework [Planning Guidance for Recovery Following Biological Incidents (DHS and EPA 2009)]—which considered Raber et al. (2002) in its development—but takes the framework to a more operational level and provides guidance at key action and decision

Stereotype threat can both enhance and impair older adults' memory.

Science.gov (United States)

Barber, Sarah J; Mather, Mara

2013-12-01

Negative stereotypes about aging can impair older adults' memory via stereotype threat; however, the mechanisms underlying this phenomenon are unclear. In two experiments, we tested competing predictions derived from two theoretical accounts of stereotype threat: executive-control interference and regulatory fit. Older adults completed a working memory test either under stereotype threat about age-related memory declines or not under such threat. Monetary incentives were manipulated such that recall led to gains or forgetting led to losses. The executive-control-interference account predicts that stereotype threat decreases the availability of executive-control resources and hence should impair working memory performance. The regulatory-fit account predicts that threat induces a prevention focus, which should impair performance when gains are emphasized but improve performance when losses are emphasized. Results were consistent only with the regulatory-fit account. Although stereotype threat significantly impaired older adults' working memory performance when remembering led to gains, it significantly improved performance when forgetting led to losses.

The consequences of chronic stereotype threat: domain disidentification and abandonment.

Science.gov (United States)

Woodcock, Anna; Hernandez, Paul R; Estrada, Mica; Schultz, P Wesley

2012-10-01

Stereotype threat impairs performance across many domains. Despite a wealth of research, the long-term consequences of chronic stereotype threat have received little empirical attention. Beyond the immediate impact on performance, the experience of chronic stereotype threat is hypothesized to lead to domain disidentification and eventual domain abandonment. Stereotype threat is 1 explanation why African Americans and Hispanic/Latino(a)s "leak" from each juncture of the academic scientific pipeline in disproportionately greater numbers than their White and Asian counterparts. Using structural equation modeling, we tested the stereotype threat-disidentification hypothesis across 3 academic years with a national longitudinal panel of undergraduate minority science students. Experience of stereotype threat was associated with scientific disidentification, which in turn predicted a significant decline in the intention to pursue a scientific career. Race/ethnicity moderated this effect, whereby the effect was evident for Hispanic/Latino(a) students but not for all African American students. We discuss findings in terms of understanding chronic stereotype threat.

Anxiety and Depression Symptom Dimensions Demonstrate Unique Relationships with the Startle Reflex in Anticipation of Unpredictable Threat in 8 to 14 Year-Old Girls

Science.gov (United States)

Nelson, Brady D.; Hajcak, Greg

2016-01-01

There is growing evidence that heightened sensitivity to unpredictability is a core mechanism of anxiety disorders. In adults, multiple anxiety disorders have been associated with a heightened startle reflex in anticipation of unpredictable threat. Child and adolescent anxiety has been linked to an increased startle reflex across baseline, safety, and threat conditions. However, it is unclear whether anxiety in youth is related to the startle reflex as a function of threat predictability. In a sample of 90 8 to 14 year-old girls, the present study examined the association between anxiety symptom dimensions and startle potentiation during a no, predictable, and unpredictable threat task. Depression symptom dimensions were also examined given their high comorbidity with anxiety and mixed relationship with the startle reflex and sensitivity to unpredictability. To assess current symptoms, participants completed the self-report Screen for Child Anxiety Related Emotional Disorders and Children’s Depression Inventory. Results indicated that social phobia symptoms were associated with heightened startle potentiation in anticipation of unpredictable threat and attenuated startle potentiation in anticipation of predictable threat. Negative mood and negative self-esteem symptoms were associated with attenuated and heightened startle potentiation in anticipation of unpredictable threat, respectively. All results remained significant after controlling for the other symptom dimensions. The present study provides initial evidence that anxiety and depression symptom dimensions demonstrate unique associations with the startle reflex in anticipation of unpredictable threat in children and adolescents. PMID:27224989

41 CFR 60-741.22 - Direct threat defense.

Science.gov (United States)

2010-07-01

... INDIVIDUALS WITH DISABILITIES Discrimination Prohibited § 60-741.22 Direct threat defense. The contractor may... individual or others in the workplace. (See § 60-741.2(y) defining direct threat.) ...

The CBRNE Threat Needs New Dedicated Analysers

International Nuclear Information System (INIS)

Stienstra, S.

2007-01-01

Introduction: After the 9-11 attack by terrorists several governments realized their vulnerability towards creative asymmetric attacks. Due to increasing complexity of our society we create more vulnerability towards terror attacks. More chemical substances than we realize can be misused to destabilize our modern society. Recently aircraft passengers were confronted with new regulations, which limit the amount of fluid, which a passenger can bring on board with hand luggage. How far should we go limiting the allowance to bring liquids and substances on board? It indicates that we need new analytic instruments for screening the safety of luggage in all types of transport. Study Design: An inventory was made of the present demand for safe transport and its vulnerability to terror attacks. Also the safety and safety awareness in public buildings, offices and industrial complexes was assessed. Knowing the demand for a certain safety level, an inventory was made to identify analytical equipment, which can be used to check passengers and luggage on possible threats. The same can be used for protecting public areas, offices and industrial complexes. Results And Discussion: It is amazing how some governments, financially driven, underestimate the consequences of CBRNE incidences and disasters. Both threats due to release of dangerous substances just by accident and deliberate abuse of chemicals and/or biologicals by terror organizations is underestimated. Financial rationales are often the cause that the preparedness is less that technically could be possible. Still some commercial companies realize the importance of safety and preparedness towards terror attacks and take their precautions. Several detection systems are now under development and a new market of safety devices comes into existence. Conclusion: Key question is how far we would like to go with defending us with technical devices against potential terror attacks. Also the design of buildings, transport

Biological invasions on oceanic islands: Implications for island ecosystems and avifauna

Science.gov (United States)

Dean E. Pearson

2009-01-01

Biological invasions present a global threat to biodiversity, but oceanic islands are the systems hardest hit by invasions. Islands are generally depauperate in species richness, trophic complexity, and functional diversity relative to comparable mainland ecosystems. This situation results in low biotic resistance to invasion and many empty niches for invaders to...

Identifying key conservation threats to Alpine birds through expert knowledge

Science.gov (United States)

Pedrini, Paolo; Brambilla, Mattia; Rolando, Antonio; Girardello, Marco

2016-01-01

Alpine biodiversity is subject to a range of increasing threats, but the scarcity of data for many taxa means that it is difficult to assess the level and likely future impact of a given threat. Expert opinion can be a useful tool to address knowledge gaps in the absence of adequate data. Experts with experience in Alpine ecology were approached to rank threat levels for 69 Alpine bird species over the next 50 years for the whole European Alps in relation to ten categories: land abandonment, climate change, renewable energy, fire, forestry practices, grazing practices, hunting, leisure, mining and urbanization. There was a high degree of concordance in ranking of perceived threats among experts for most threat categories. The major overall perceived threats to Alpine birds identified through expert knowledge were land abandonment, urbanization, leisure and forestry, although other perceived threats were ranked highly for particular species groups (renewable energy and hunting for raptors, hunting for gamebirds). For groups of species defined according to their breeding habitat, open habitat species and treeline species were perceived as the most threatened. A spatial risk assessment tool based on summed scores for the whole community showed threat levels were highest for bird communities of the northern and western Alps. Development of the approaches given in this paper, including addressing biases in the selection of experts and adopting a more detailed ranking procedure, could prove useful in the future in identifying future threats, and in carrying out risk assessments based on levels of threat to the whole bird community. PMID:26966659

Identifying key conservation threats to Alpine birds through expert knowledge

Directory of Open Access Journals (Sweden)

Dan E. Chamberlain

2016-02-01

Full Text Available Alpine biodiversity is subject to a range of increasing threats, but the scarcity of data for many taxa means that it is difficult to assess the level and likely future impact of a given threat. Expert opinion can be a useful tool to address knowledge gaps in the absence of adequate data. Experts with experience in Alpine ecology were approached to rank threat levels for 69 Alpine bird species over the next 50 years for the whole European Alps in relation to ten categories: land abandonment, climate change, renewable energy, fire, forestry practices, grazing practices, hunting, leisure, mining and urbanization. There was a high degree of concordance in ranking of perceived threats among experts for most threat categories. The major overall perceived threats to Alpine birds identified through expert knowledge were land abandonment, urbanization, leisure and forestry, although other perceived threats were ranked highly for particular species groups (renewable energy and hunting for raptors, hunting for gamebirds. For groups of species defined according to their breeding habitat, open habitat species and treeline species were perceived as the most threatened. A spatial risk assessment tool based on summed scores for the whole community showed threat levels were highest for bird communities of the northern and western Alps. Development of the approaches given in this paper, including addressing biases in the selection of experts and adopting a more detailed ranking procedure, could prove useful in the future in identifying future threats, and in carrying out risk assessments based on levels of threat to the whole bird community.

Plague in Egypt: Disease biology, history and contemporary analysis: A minireview

Directory of Open Access Journals (Sweden)

Wael M. Lotfy

2015-07-01

Full Text Available Plague is a zoonotic disease with a high mortality rate in humans. Unfortunately, it is still endemic in some parts of the world. Also, natural foci of the disease are still found in some countries. Thus, there may be a risk of global plague re-emergence. This work reviews plague biology, history of major outbreaks, and threats of disease re-emergence in Egypt. Based on the suspected presence of potential natural foci in the country, the global climate change, and the threat posed by some neighbouring countries disease re-emergence in Egypt should not be excluded. The country is in need for implementation of some preventive measures.

Threat ≠ prevention, challenge ≠ promotion: the impact of threat, challenge and regulatory focus on attention to negative stimuli.

Science.gov (United States)

Sassenberg, Kai; Sassenrath, Claudia; Fetterman, Adam K

2015-01-01

The purpose of the current experiment was to distinguish between the impact of strategic and affective forms of gain- and loss-related motivational states on the attention to negative stimuli. On the basis of the counter-regulation principle and regulatory focus theory, we predicted that individuals would attend more to negative than to neutral stimuli in a prevention focus and when experiencing challenge, but not in a promotion focus and under threat. In one experiment (N = 88) promotion, prevention, threat, or challenge states were activated through a memory task, and a subsequent dot probe task was administered. As predicted, those in the prevention focus and challenge conditions had an attentional bias towards negative words, but those in promotion and threat conditions did not. These findings provide support for the idea that strategic mindsets (e.g., regulatory focus) and hot emotional states (e.g., threat vs. challenge) differently affect the processing of affective stimuli.

The Effects of Gain- versus Loss-Framed Messages Following Health Risk Information on Physical Activity in Individuals With Multiple Sclerosis.

Science.gov (United States)

Lithopoulos, Alexander; Bassett-Gunter, Rebecca L; Martin Ginis, Kathleen A; Latimer-Cheung, Amy E

2017-06-01

Few people with multiple sclerosis engage in physical activity. Messaging interventions may motivate more physical activity among these individuals. The purpose of this online study was to evaluate an intervention presenting participants with multiple sclerosis (N = 237) with risk information (i.e., information demonstrating people with multiple sclerosis are more likely to experience certain health issues) or no risk information followed by gain- or loss-framed physical activity messages. Participants completed questionnaires on Days 1, 6, and 28 and received information material on Days 2-5. The dependent variables were as follows: physical activity intentions and behavior, response and task efficacy, perceived threat (i.e., perception of threat to health issues relevant to people with multiple sclerosis), and avoidance (i.e., avoiding thinking about/doing something about the health issues presented in the messages). Analyses indicated physical activity and response efficacy increased over time. Also, participants receiving risk information had higher levels of physical activity and perceived threat. However, manipulation checks showed no differences between participants regarding perceptions of risk information or gain/loss-framed messages. Despite the lack of impact of the framing intervention, this study suggests that a brief informational intervention can positively influence physical activity and certain correlates of physical activity among people with multiple sclerosis.

Environmental and health impacts of fine and ultrafine metallic particles: Assessment of threat scores

Energy Technology Data Exchange (ETDEWEB)

Goix, Sylvaine [Université de Toulouse, INP-ENSAT, Av. Agrobiopôle, 31326 Castanet-Tolosan (France); UMR 5245 CNRS-INP-UPS, EcoLab (Laboratoire d' écologie fonctionnelle), Avenue de l' Agrobiopôle, BP 32607, 31326 Castanet-Tolosan (France); Lévêque, Thibaut [Université de Toulouse, INP-ENSAT, Av. Agrobiopôle, 31326 Castanet-Tolosan (France); UMR 5245 CNRS-INP-UPS, EcoLab (Laboratoire d' écologie fonctionnelle), Avenue de l' Agrobiopôle, BP 32607, 31326 Castanet-Tolosan (France); ADEME (French Agency for Environment and Energy Management), 20 Avenue du Grésillé, BP 90406, 49004 Angers Cedex 01 (France); Xiong, Tian-Tian [Université de Toulouse, INP-ENSAT, Av. Agrobiopôle, 31326 Castanet-Tolosan (France); UMR 5245 CNRS-INP-UPS, EcoLab (Laboratoire d' écologie fonctionnelle), Avenue de l' Agrobiopôle, BP 32607, 31326 Castanet-Tolosan (France); Schreck, Eva [Géosciences Environnement Toulouse (GET), Observatoire Midi Pyrénées, Université de Toulouse, CNRS, IRD, 14 Avenue E. Belin, F-31400 Toulouse (France); and others

2014-08-15

This study proposes global threat scores to prioritize the harmfulness of anthropogenic fine and ultrafine metallic particles (FMP) emitted into the atmosphere at the global scale. (Eco)toxicity of physicochemically characterized FMP oxides for metals currently observed in the atmosphere (CdO, CuO, PbO, PbSO{sub 4}, Sb{sub 2}O{sub 3}, and ZnO) was assessed by performing complementary in vitro tests: ecotoxicity, human bioaccessibility, cytotoxicity, and oxidative potential. Using an innovative methodology based on the combination of (eco)toxicity and physicochemical results, the following hazard classification of the particles is proposed: CdCl{sub 2}∼CdO>CuO>PbO>ZnO>PbSO{sub 4}>Sb{sub 2}O{sub 3}. Both cadmium compounds exhibited the highest threat score due to their high cytotoxicity and bioaccessible dose, whatever their solubility and speciation, suggesting that cadmium toxicity is due to its chemical form rather than its physical form. In contrast, the Sb{sub 2}O{sub 3} threat score was the lowest due to particles with low specific area and solubility, with no effects except a slight oxidative stress. As FMP physicochemical properties reveal differences in specific area, crystallization systems, dissolution process, and speciation, various mechanisms may influence their biological impact. Finally, this newly developed and global approach could be widely used in various contexts of pollution by complex metal particles and may improve risk management. - Highlights: • Seven micro- and nano- monometallic characterized particles were studied as references. • Bioaccessibility, eco and cytotoxicity, and oxidative potential assays were performed. • According to calculated threat scores: CdCl{sub 2}∼CdO>CuO>PbO>ZnO>PbSO{sub 4}>Sb{sub 2}O{sub 3}.

The emerging threat of superwarfarins: history, detection, mechanisms, and countermeasures: The emerging threat of superwarfarins

Energy Technology Data Exchange (ETDEWEB)

Feinstein, Douglas L. [Department of Anesthesiology, University of Illinois, Chicago Illinois; Jesse Brown VA Medical Center, Chicago Illinois; Akpa, Belinda S. [Department of Molecular Biomedical Sciences, North Carolina State University, Raleigh North Carolina; Ayee, Manuela A. [Department of Medicine, University of Illinois, Chicago Illinois; Boullerne, Anne I. [Department of Anesthesiology, University of Illinois, Chicago Illinois; Jesse Brown VA Medical Center, Chicago Illinois; Braun, David [Department of Anesthesiology, University of Illinois, Chicago Illinois; Brodsky, Sergey V. [Department of Pathology, the Ohio State University, Columbus Ohio; Gidalevitz, David [Department of Physics and the Center for the Molecular Study of Condensed Soft Matter, Illinois Institute of Technology, Chicago Illinois; Hauck, Zane [Department of Medicinal Chemistry and Pharmacognosy, University of Illinois, Chicago Illinois; Kalinin, Sergey [Department of Anesthesiology, University of Illinois, Chicago Illinois; Kowal, Kathy [Department of Anesthesiology, University of Illinois, Chicago Illinois; Kuzmenko, Ivan [X-ray Science Division, Argonne National Laboratory, Lemont Illinois; Lis, Kinga [Department of Anesthesiology, University of Illinois, Chicago Illinois; Marangoni, Natalia [Department of Anesthesiology, University of Illinois, Chicago Illinois; Martynowycz, Michael W. [Department of Physics and the Center for the Molecular Study of Condensed Soft Matter, Illinois Institute of Technology, Chicago Illinois; X-ray Science Division, Argonne National Laboratory, Lemont Illinois; Rubinstein, Israel [Department of Anesthesiology, University of Illinois, Chicago Illinois; Department of Medicine, University of Illinois, Chicago Illinois; van Breemen, Richard [Department of Anesthesiology, University of Illinois, Chicago Illinois; Ware, Kyle [Department of Pathology, the Ohio State University, Columbus Ohio; Weinberg, Guy [Department of Anesthesiology, University of Illinois, Chicago Illinois; Jesse Brown VA Medical Center, Chicago Illinois

2016-05-31

Superwarfarins were developed following the emergence of warfarin resistance in rodents. Compared to warfarin, superwarfarins have much longer half-lives and stronger affinity to vitamin K epoxide reductase and therefore can cause death in warfarin-resistant rodents. By the mid-1970s, the superwarfarins brodifacoum and difenacoum were the most widely used rodenticides throughout the world. Unfortunately, increased use was accompanied by a rise in accidental poisonings, reaching >16,000 per year in the United States. Risk of exposure has become a concern since large quantities, up to hundreds of kilograms of rodent bait, are applied by aerial dispersion over regions with rodent infestations. Reports of intentional use of superwarfarins in civilian and military scenarios raise the specter of larger incidents or mass casualties. Unlike warfarin overdose, for which 1–2 days of treatment with vitamin K is effective, treatment of superwarfarin poisoning with vitamin K is limited by extremely high cost and can require daily treatment for a year or longer. Furthermore, superwarfarins have actions that are independent of their anticoagulant effects, including both vitamin K–dependent and –independent effects,which are not mitigated by vitaminKtherapy. In this review, we summarize superwarfarin development, biology and pathophysiology, their threat as weapons, and possible therapeutic approaches.

Population structure, behavior, and current threats to the sarus crane (Grus antigone antigone in Nepal

Directory of Open Access Journals (Sweden)

Kamal Raj Gosai

2016-09-01

Full Text Available The sarus crane (Grus antigone antigone is listed as “vulnerable” in the International Union for Conservation of Nature (IUCN Red List of Threatened Species. Sarus cranes are distributed in the lowlands, but most live outside protected areas, especially in agricultural areas and wetlands of Nepal. The continuous expansion of agricultural land and the reduction of wetland habitats pose the greatest threats to the conservation of the species. We studied the sarus crane in the Rupandehi District of Nepal to understand their population structure, behavior, and current threats. We used the line (i.e., road transect method from August 2013 to February 2014. The study area contained 147 sarus cranes. Agricultural land and wetland areas contained the highest number of sarus cranes. Our analysis showed that the population of sarus crane in the area has declined since 2007. Most sarus cranes lived in pairs. A single flock contained 13 cranes at maximum. Sarus crane behavior was not significantly different before and after the breeding seasons. Human–sarus crane conflict began when cranes started utilizing agricultural areas. The main threats to the hatching success and survival of sarus cranes in the Rupendehi District are egg theft and the hunting of cranes for meat. The findings of this study establish baseline information on the overall conservation status, habitat availability, and ecological behavior of sarus cranes in the district. We propose regular surveys to monitor sarus crane population levels in the face of multiple anthropogenic threats to their survival.

The Consequences of Chronic Stereotype Threat: Domain Disidentification and Abandonment

OpenAIRE

Woodcock, Anna; Hernandez, Paul R.; Estrada, Mica; Schultz, P. Wesley

2012-01-01

Stereotype threat impairs performance across many domains. Despite a wealth of research, the long-term consequences of chronic stereotype threat have received little empirical attention. Beyond the immediate impact on performance, the experience of chronic stereotype threat is hypothesized to lead to domain disidentification and eventual domain abandonment. Stereotype threat is 1 explanation why African Americans and Hispanic/Latino(a)s “leak” from each juncture of the academic scientific pip...

Gender gaps in achievement and participation in multiple introductory biology classrooms.

Science.gov (United States)

Eddy, Sarah L; Brownell, Sara E; Wenderoth, Mary Pat

2014-01-01

Although gender gaps have been a major concern in male-dominated science, technology, engineering, and mathematics disciplines such as physics and engineering, the numerical dominance of female students in biology has supported the assumption that gender disparities do not exist at the undergraduate level in life sciences. Using data from 23 large introductory biology classes for majors, we examine two measures of gender disparity in biology: academic achievement and participation in whole-class discussions. We found that females consistently underperform on exams compared with males with similar overall college grade point averages. In addition, although females on average represent 60% of the students in these courses, their voices make up less than 40% of those heard responding to instructor-posed questions to the class, one of the most common ways of engaging students in large lectures. Based on these data, we propose that, despite numerical dominance of females, gender disparities remain an issue in introductory biology classrooms. For student retention and achievement in biology to be truly merit based, we need to develop strategies to equalize the opportunities for students of different genders to practice the skills they need to excel. © 2014 S. L. Eddy et al. CBE—Life Sciences Education © 2014 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

Practice makes pretty good: assessment of primary literature reading abilities across multiple large-enrollment biology laboratory courses.

Science.gov (United States)

Sato, Brian K; Kadandale, Pavan; He, Wenliang; Murata, Paige M N; Latif, Yama; Warschauer, Mark

2014-01-01

Primary literature is essential for scientific communication and is commonly utilized in undergraduate biology education. Despite this, there is often little time spent training our students how to critically analyze a paper. To address this, we introduced a primary literature module in multiple upper-division laboratory courses. In this module, instructors conduct classroom discussions that dissect a paper as researchers do. While previous work has identified classroom interventions that improve primary literature comprehension within a single course, our goal was to determine whether including a scientific paper module in our classes could produce long-term benefits. On the basis of performance in an assessment exam, we found that our module resulted in longitudinal gains, including increased comprehension and critical-thinking abilities in subsequent lab courses. These learning gains were specific to courses utilizing our module, as no longitudinal gains were seen in students who had taken other upper-division labs that lacked extensive primary literature discussion. In addition, we assessed whether performance on our assessment correlated with a variety of factors, including grade point average, course performance, research background, and self-reported confidence in understanding of the article. Furthermore, all of the study conclusions are independent of biology disciplines, as we observe similar trends within each course. © 2014 B. K. Sato et al. CBE—Life Sciences Education © 2014 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

Spatial patterns of carbon, biodiversity, deforestation threat, and REDD+ projects in Indonesia.

Science.gov (United States)

Murray, Josil P; Grenyer, Richard; Wunder, Sven; Raes, Niels; Jones, Julia P G

2015-10-01

There are concerns that Reduced Emissions from Deforestation and forest Degradation (REDD+) may fail to deliver potential biodiversity cobenefits if it is focused on high carbon areas. We explored the spatial overlaps between carbon stocks, biodiversity, projected deforestation threats, and the location of REDD+ projects in Indonesia, a tropical country at the forefront of REDD+ development. For biodiversity, we assembled data on the distribution of terrestrial vertebrates (ranges of amphibians, mammals, birds, reptiles) and plants (species distribution models for 8 families). We then investigated congruence between different measures of biodiversity richness and carbon stocks at the national and subnational scales. Finally, we mapped active REDD+ projects and investigated the carbon density and potential biodiversity richness and modeled deforestation pressures within these forests relative to protected areas and unprotected forests. There was little internal overlap among the different hotspots (richest 10% of cells) of species richness. There was also no consistent spatial congruence between carbon stocks and the biodiversity measures: a weak negative correlation at the national scale masked highly variable and nonlinear relationships island by island. Current REDD+ projects were preferentially located in areas with higher total species richness and threatened species richness but lower carbon densities than protected areas and unprotected forests. Although a quarter of the total area of these REDD+ projects is under relatively high deforestation pressure, the majority of the REDD+ area is not. In Indonesia at least, first-generation REDD+ projects are located where they are likely to deliver biodiversity benefits. However, if REDD+ is to deliver additional gains for climate and biodiversity, projects will need to focus on forests with the highest threat to deforestation, which will have cost implications for future REDD+ implementation. © 2015 The Authors

The Smallpox Threat: The School Nurse's Role

Science.gov (United States)

Martin, Mary E.; Didion, Judy

2003-01-01

Today, with the threat of bioterrorism and war, there is a new dimension to the traditional role of the school nurse. The smallpox threat to public health will invoke the school nurse's role as an educator, liaison, and consultant in the community. This article discusses smallpox, the vaccination process, adverse effects, and postvaccination care.…

Movements Indicate Threat Response Phases in Children at Risk for Anxiety.

Science.gov (United States)

McGinnis, Ellen W; McGinnis, Ryan S; Muzik, Maria; Hruschak, Jessica; Lopez-Duran, Nestor L; Perkins, Noel C; Fitzgerald, Kate; Rosenblum, Katherine L

2017-09-01

Temporal phases of threat response, including potential threat (anxiety), acute threat (startle, fear), and post-threat response modulation, have been identified as the underlying markers of anxiety disorders. Objective measures of response during these phases may help identify children at risk for anxiety; however, the complexity of current assessment techniques prevent their adoption in many research and clinical contexts. We propose an alternative technology, an inertial measurement unit (IMU), that enables noninvasive measurement of the movements associated with threat response, and test its ability to detect threat response phases in young children at a heightened risk for developing anxiety. We quantified the motion of 18 children (3-7 years old) during an anxiety-/fear-provoking behavioral task using an IMU. Specifically, measurements from a single IMU secured to the child's waist were used to extract root-mean-square acceleration and angular velocity in the horizontal and vertical directions, and tilt and yaw range of motion during each threat response phase. IMU measurements detected expected differences in child motion by threat phase. Additionally, potential threat motion was positively correlated to familial anxiety risk, startle range of motion was positively correlated with child internalizing symptoms, and response modulation motion was negatively correlated to familial anxiety risk. Results suggest differential theory-driven threat response phases and support previous literature connecting maternal child risk to anxiety with behavioral measures using more feasible objective methods. This is the first study demonstrating the utility of an IMU for characterizing the motion of young children to mark the phases of threat response modulation. The technique provides a novel and objective measure of threat response for mental health researchers.

Biological Studies of Posttraumatic Stress Disorder

Science.gov (United States)

Pitman, Roger K.; Rasmusson, Ann M.; Koenen, Karestan C.; Shin, Lisa M.; Orr, Scott P.; Gilbertson, Mark W.; Milad, Mohammed R.; Liberzon, Israel

2016-01-01

Preface Posttraumatic stress disorder (PTSD) is the only major mental disorder for which a cause is considered to be known, viz., an event that involves threat to the physical integrity of oneself or others and induces a response of intense fear, helplessness, or horror. Although PTSD is still largely regarded as a psychological phenomenon, over the past three decades the growth of the biological PTSD literature has been explosive, and thousands of references now exist. Ultimately, the impact of an environmental event, such as a psychological trauma, must be understood at organic, cellular, and molecular levels. The present review attempts to present the current state of this understanding, based upon psychophysiological, structural and functional neuroimaging, endocrinological, genetic, and molecular biological studies in humans and in animal models. PMID:23047775

"Unreliability as a threat to understanding psychopathology: The cautionary tale of attentional bias": Correction to Rodebaugh et al. (2016).

Science.gov (United States)

2016-10-01

Reports an error in "Unreliability as a threat to understanding psychopathology: The cautionary tale of attentional bias" by Thomas L. Rodebaugh, Rachel B. Scullin, Julia K. Langer, David J. Dixon, Jonathan D. Huppert, Amit Bernstein, Ariel Zvielli and Eric J. Lenze ( Journal of Abnormal Psychology , 2016[Aug], Vol 125[6], 840-851). There was an error in the Author Note concerning the support of the MacBrain Face Stimulus Set. The correct statement is provided. (The following abstract of the original article appeared in record 2016-30117-001.) The use of unreliable measures constitutes a threat to our understanding of psychopathology, because advancement of science using both behavioral and biologically oriented measures can only be certain if such measurements are reliable. Two pillars of the National Institute of Mental Health's portfolio-the Research Domain Criteria (RDoC) initiative for psychopathology and the target engagement initiative in clinical trials-cannot succeed without measures that possess the high reliability necessary for tests involving mediation and selection based on individual differences. We focus on the historical lack of reliability of attentional bias measures as an illustration of how reliability can pose a threat to our understanding. Our own data replicate previous findings of poor reliability for traditionally used scores, which suggests a serious problem with the ability to test theories regarding attentional bias. This lack of reliability may also suggest problems with the assumption (in both theory and the formula for the scores) that attentional bias is consistent and stable across time. In contrast, measures accounting for attention as a dynamic process in time show good reliability in our data. The field is sorely in need of research reporting findings and reliability for attentional bias scores using multiple methods, including those focusing on dynamic processes over time. We urge researchers to test and report reliability of

Anxiety and Depression Symptom Dimensions Demonstrate Unique Relationships with the Startle Reflex in Anticipation of Unpredictable Threat in 8 to 14 Year-Old Girls.

Science.gov (United States)

Nelson, Brady D; Hajcak, Greg

2017-02-01

There is growing evidence that heightened sensitivity to unpredictability is a core mechanism of anxiety disorders. In adults, multiple anxiety disorders have been associated with a heightened startle reflex in anticipation of unpredictable threat. Child and adolescent anxiety has been linked to an increased startle reflex across baseline, safety, and threat conditions. However, it is unclear whether anxiety in youth is related to the startle reflex as a function of threat predictability. In a sample of 90 8 to 14 year-old girls, the present study examined the association between anxiety symptom dimensions and startle potentiation during a no, predictable, and unpredictable threat task. Depression symptom dimensions were also examined given their high comorbidity with anxiety and mixed relationship with the startle reflex and sensitivity to unpredictability. To assess current symptoms, participants completed the self-report Screen for Child Anxiety Related Emotional Disorders and Children's Depression Inventory. Results indicated that social phobia symptoms were associated with heightened startle potentiation in anticipation of unpredictable threat and attenuated startle potentiation in anticipation of predictable threat. Negative mood and negative self-esteem symptoms were associated with attenuated and heightened startle potentiation in anticipation of unpredictable threat, respectively. All results remained significant after controlling for the other symptom dimensions. The present study provides initial evidence that anxiety and depression symptom dimensions demonstrate unique associations with the startle reflex in anticipation of unpredictable threat in children and adolescents.

Toxicological Threats of Plastic

Science.gov (United States)

Plastics pose both physical (e.g., entanglement, gastrointestinal blockage, reef destruction) and chemical threats (e.g., bioaccumulation of the chemical ingredients of plastic or toxic chemicals sorbed to plastics) to wildlife and the marine ecosystem.

Biological diversity, ecology and global climate change

International Nuclear Information System (INIS)

Jutro, P.R.

1991-01-01

Worldwide climate change and loss of biodiversity are issues of global scope and importance that have recently become subjects of considerable public concern. Their perceived threat lies in their potential to disrupt ecological functioning and stability rather than from any direct threat they may pose to human health. Over the last 5 years, the international scientific community and the general public have become aware of the implications that atmospheric warming might have for world climate patterns and the resulting changes in the persistence, location, and composition of ecosystems worldwide. Human activities are currently responsible for a species loss rate that is the most extreme in millions of years, and an alarmingly increasing rate of transformation and fragmentation of natural landscapes. In the case of both global warming and reduction of biological diversity, man is affecting nature in an unprecedented fashion, on a global scale, and with unpredictable and frequently irreversible results

External Threat Risk Assessment Algorithm (ExTRAA)

Energy Technology Data Exchange (ETDEWEB)

Powell, Troy C. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2017-08-01

Two risk assessment algorithms and philosophies have been augmented and combined to form a new algorit hm, the External Threat Risk Assessment Algorithm (ExTRAA), that allows for effective and statistically sound analysis of external threat sources in relation to individual attack methods . In addition to the attack method use probability and the attack method employment consequence, t he concept of defining threat sources is added to the risk assessment process. Sample data is tabulated and depicted in radar plots and bar graphs for algorithm demonstration purposes. The largest success of ExTRAA is its ability to visualize the kind of r isk posed in a given situation using the radar plot method.

Radiological threat, public and media: a psychosociological view

Energy Technology Data Exchange (ETDEWEB)

Arciszewski, T. [University Rene Descartes - Paris 5, 92 - Boulogne (France)

2006-07-01

Nuclear risk has become a major social communication along the 20. century because of its critical socio-political impact. That communication is not limited to expert speeches and simple acceptation. The way people understand that kind of threat is based on beliefs and on imaginary pictures. Consequently, and because it shapes people attitude, expectations and behaviours, their analysis is a key for policy and prevention. We will present, in the light of the research on risk perception and social psychology theoretical background, how people can manage with the nuclear fear. Some particular points will be studied: the nature of nuclear threat and fear, the cultural and media coverage and the consequences of this threat on behaviour. We will first focus on what a societal threat is and of which nature is the nuclear threat. We will rely on statistical data on risk perception. We have to consider the two main fields of information: first the nuclear threat as a mass destruction weapon and second, the radiological risk as a consequence of civil use of radiological material. Those two aspects, deeply related for most people, make the roots for the described fears. Then, the perception of the risks relative to nuclear is necessarily influenced by this representation. The representation of the nuclear power is and will be for next years, related to the nuclear mushroom as experimentally pointed o ut by Fiske, both with the abnormal children of Chernobyl. How can we change that vision? Not to be a liar, it will be hard work because it a old story, a long construction of what will be the future of mankind, something deeply influenced by media, movie, geopolitical facts like the cold war or technological accident like Three Mile Island or Chernobyl. It has to deal with the problem of media transmission of fears, which is a problem in itself, but due to the scientific base of our problem, particularly relevant. Moreover, there is a strong cultural background that maintains

Radiological threat, public and media: a psychosociological view

International Nuclear Information System (INIS)

Arciszewski, T.

2006-01-01

Nuclear risk has become a major social communication along the 20. century because of its critical socio-political impact. That communication is not limited to expert speeches and simple acceptation. The way people understand that kind of threat is based on beliefs and on imaginary pictures. Consequently, and because it shapes people attitude, expectations and behaviours, their analysis is a key for policy and prevention. We will present, in the light of the research on risk perception and social psychology theoretical background, how people can manage with the nuclear fear. Some particular points will be studied: the nature of nuclear threat and fear, the cultural and media coverage and the consequences of this threat on behaviour. We will first focus on what a societal threat is and of which nature is the nuclear threat. We will rely on statistical data on risk perception. We have to consider the two main fields of information: first the nuclear threat as a mass destruction weapon and second, the radiological risk as a consequence of civil use of radiological material. Those two aspects, deeply related for most people, make the roots for the described fears. Then, the perception of the risks relative to nuclear is necessarily influenced by this representation. The representation of the nuclear power is and will be for next years, related to the nuclear mushroom as experimentally pointed o ut by Fiske, both with the abnormal children of Chernobyl. How can we change that vision? Not to be a liar, it will be hard work because it a old story, a long construction of what will be the future of mankind, something deeply influenced by media, movie, geopolitical facts like the cold war or technological accident like Three Mile Island or Chernobyl. It has to deal with the problem of media transmission of fears, which is a problem in itself, but due to the scientific base of our problem, particularly relevant. Moreover, there is a strong cultural background that maintains

Threat affects risk preferences in movement decision making

Science.gov (United States)

O'Brien, Megan K.; Ahmed, Alaa A.

2015-01-01

Emotional states such as sadness, anger, and threat have been shown to play a critical role in decision-making processes. Here we addressed the question of whether risk preferences are influenced by postural threat and whether this influence generalizes across motor tasks. We examined risk attitudes in the context of arm-reaching (ARM) and whole-body (WB) leaning movements, expecting that increased postural threat would lead to proportionally similar changes in risk-sensitivity for each motor task. Healthy young adults were shown a series of two-alternative forced-choice lotteries, where they were asked to choose between a riskier lottery and a safer lottery on each trial. Our lotteries consisted of different monetary rewards and target sizes. Subjects performed each choice task at ground level and atop an elevated platform. In the presence of this postural threat, increased physiological arousal was correlated with decreased movement variability. To determine risk-sensitivity, we quantified the frequency with which a subject chose the riskier lottery and fit lottery responses to a choice model based on cumulative prospect theory (CPT). Subjects exhibited idiosyncratic changes in risk-sensitivity between motor tasks and between elevations. However, we found that overweighting of small probabilities increased with postural threat in the WB task, indicating a more cautious, risk-averse strategy is ascribed to the possibility of a fall. Subjects were also more risk-seeking in the WB movements than in ARM at low elevation; this behavior does not seem to derive from consistent distortions in utility or probability representations but may be explained by subjects' inaccurate estimation of their own motor variability. Overall, our findings suggest that implicit threat can modify risk attitudes in the motor domain, and the threat may induce risk-aversion in salient movement tasks. PMID:26106311

Threat affects risk preferences in movement decision making

Directory of Open Access Journals (Sweden)

Megan K. O'Brien

2015-06-01

Full Text Available Emotional states such as sadness, anger, and threat have been shown to play a critical role in decision-making processes. Here we addressed the question of whether risk preferences are influenced by postural threat and whether this influence generalizes across motor tasks. We examined risk attitudes in the context of arm-reaching and whole-body leaning movements, expecting that increased postural threat would lead to proportionally similar changes in risk-sensitivity for each motor task. Healthy young adults were shown a series of two-alternative forced-choice lotteries, where they were asked to choose between a riskier lottery and a safer lottery on each trial. Our lotteries consisted of different monetary rewards and target sizes. Subjects performed each choice task at ground level and atop an elevated platform. In the presence of this postural threat, increased physiological arousal was correlated with decreased movement variability. To determine risk-sensitivity, we quantified the frequency with which a subject chose the riskier lottery and fit lottery responses to a choice model based on cumulative prospect theory. Subjects exhibited idiosyncratic changes in risk-sensitivity between motor tasks and between elevations. However, we found that overweighting of small probabilities increased with postural threat in the whole-body task, indicating a more cautious, risk-averse strategy is ascribed to the possibility of a fall. Subjects were also more risk-seeking in the whole-body movements than in arm-reaching at low elevation; this behavior does not seem to derive from consistent distortions in utility or probability representations but may be explained by subjects’ inaccurate estimation of their own motor variability. Overall, our findings suggest that implicit threat can modify risk attitudes in the motor domain, and the threat may induce risk-aversion in salient movement tasks.

Threat affects risk preferences in movement decision making.

Science.gov (United States)

O'Brien, Megan K; Ahmed, Alaa A

2015-01-01

Emotional states such as sadness, anger, and threat have been shown to play a critical role in decision-making processes. Here we addressed the question of whether risk preferences are influenced by postural threat and whether this influence generalizes across motor tasks. We examined risk attitudes in the context of arm-reaching (ARM) and whole-body (WB) leaning movements, expecting that increased postural threat would lead to proportionally similar changes in risk-sensitivity for each motor task. Healthy young adults were shown a series of two-alternative forced-choice lotteries, where they were asked to choose between a riskier lottery and a safer lottery on each trial. Our lotteries consisted of different monetary rewards and target sizes. Subjects performed each choice task at ground level and atop an elevated platform. In the presence of this postural threat, increased physiological arousal was correlated with decreased movement variability. To determine risk-sensitivity, we quantified the frequency with which a subject chose the riskier lottery and fit lottery responses to a choice model based on cumulative prospect theory (CPT). Subjects exhibited idiosyncratic changes in risk-sensitivity between motor tasks and between elevations. However, we found that overweighting of small probabilities increased with postural threat in the WB task, indicating a more cautious, risk-averse strategy is ascribed to the possibility of a fall. Subjects were also more risk-seeking in the WB movements than in ARM at low elevation; this behavior does not seem to derive from consistent distortions in utility or probability representations but may be explained by subjects' inaccurate estimation of their own motor variability. Overall, our findings suggest that implicit threat can modify risk attitudes in the motor domain, and the threat may induce risk-aversion in salient movement tasks.

Can experience overcome stereotypes in times of terror threat?

Directory of Open Access Journals (Sweden)

Mirya R. Holman

2017-02-01

Full Text Available Research on evaluations of leaders has frequently found that female leaders receive lower ratings in times of national security crisis. However, less is known about countervailing factors. We contend that partisanship and leadership experience in relevant domains are two factors that can counteract the negative effects of terrorist threat on evaluations of female political leaders. To test this expectation, we implemented a national study in 2012 containing terrorist threat and non-threat conditions, and then asked participants to evaluate political leaders. The results show that Republican leaders, including women, are unaffected by terrorist threat; in contrast, Democratic leaders are punished during times of terrorist threat, but this negative effect is smaller for then-Secretary of State Hillary Clinton compared to Nancy Pelosi, who lacks similar experience. In short, Republican partisanship is a strong countervailing factor, while leadership experience in national security more modestly countervails.

Relationships Among Attention Networks and Physiological Responding to Threat

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Sarapas, Casey; Weinberg, Anna; Langenecker, Scott A.

2016-01-01

Although researchers have long hypothesized a relationship between attention and anxiety, theoretical and empirical accounts of this relationship have conflicted. We attempted to resolve these conflicts by examining relationships of attentional abilities with responding to predictable and unpredictable threat, related but distinct motivational process implicated in a number of anxiety disorders. Eighty-one individuals completed a behavioral task assessing efficiency of three components of attention – alerting, orienting, and executive control (Attention Network Test - Revised). We also assessed startle responding during anticipation of both predictable, imminent threat (of mild electric shock) and unpredictable contextual threat. Faster alerting and slower disengaging from non-emotional attention cues were related to heightened responding to unpredictable threat, whereas poorer executive control of attention was related to heightened responding to predictable threat. This double dissociation helps to integrate models of attention and anxiety and may be informative for treatment development. PMID:27816781

Perceived control qualifies the effects of threat on prejudice.

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Greenaway, Katharine H; Louis, Winnifred R; Hornsey, Matthew J; Jones, Janelle M

2014-09-01

People sometimes show a tendency to lash out in a prejudiced manner when they feel threatened. This research shows that the relationship between threat and prejudice is moderated by people's levels of perceived control: Threat leads to prejudice only when people feel concurrently low in control. In two studies, terrorist threat was associated with heightened prejudice among people who were low in perceived control over the threat (Study 1; N = 87) or over their lives in general (Study 2; N = 2,394), but was not associated with prejudice among people who were high in perceived control. Study 3 (N = 139) replicated this finding experimentally in the context of the Global Financial Crisis. The research identifies control as an important ingredient in threatening contexts that, if bolstered, can reduce general tendencies to lash out under threat. © 2013 The British Psychological Society.

Counteracting effect of threat on reward enhancements during working memory.

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Choi, Jong Moon; Padmala, Srikanth; Pessoa, Luiz

2015-01-01

Cognitive performance has been shown to be enhanced when performance-based rewards are at stake. On the other hand, task-irrelevant threat processing has been shown to have detrimental effects during several cognitive tasks. Crucially, the impact of reward and threat on cognition has been studied largely independently of one another. Hence, our understanding of how reward and threat simultaneously contribute to performance is incomplete. To fill in this gap, the present study investigated how reward and threat interact with one another during a cognitive task. We found that threat of shock counteracted the beneficial effect of reward during a working memory task. Furthermore, individual differences in self-reported reward-sensitivity and anxiety were linked to the extent to which reward and threat interacted during behaviour. Together, the current findings contribute to a limited but growing literature unravelling how positive and negative information processing jointly influence cognition.

Assessment of Containment Structures Against Missile Impact Threats

Institute of Scientific and Technical Information of China (English)

LI Q M

2006-01-01

In order to ensure the highest safety requirements,nuclear power plant structures (the containment structures,the fuel storages and transportation systems) should be assessed against all possible internal and external impact threats.The internal impact threats include kinetic missiles generated by the failure of high pressure vessels and pipes,the failure of high speed rotating machineries and accidental drops.The external impact threats may come from airborne missiles,aircraft impact,explosion blast and fragments.The impact effects of these threats on concrete and steel structures in a nuclear power plant are discussed.Methods and procedures for the impact assessment of nuclear power plants are introduced.Recent studies on penetration and perforation mechanics as well as progresses on dynamic properties of concrete-like materials are presented to increase the understanding of the impact effects on concrete containment structures.

How agricultural multiple ecosystem services respond to socioeconomic factors in Mengyin County, China.

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Chen, Yajuan; Yu, Zhenrong; Li, Xuedong; Li, Pengyao

2018-07-15

Provisioning services have always been the main focus of agriculture, and which have led to a decline in biodiversity and have damaged a number of other services. Agriculture should contribute to current and future food security while producing multiple ecosystem services (ES). Restoration outcomes of multiple ES were affected by different socioeconomic drivers, thus a better understanding of how multiple ES respond to socioeconomic drivers can help to restore multiple ES. This paper used rural people's perceptions of ES to quantify and map ecosystem service obtainment and demand in the Mengyin County, China. An integrative index of multiple ecosystem services (IMES) was used to effectively aggregate the values of multiple ES. The threat categorization framework is designed to communicate the degree to which the adequate and sustainable provision of multiple ES is threatened, in order to prioritize conservation actions. The results revealed that 6 townships in the Mengyin County exhibited an excessive obtainment situation (demand is less than obtainment) of multiple ES; an insufficient obtainment situation (demand is greater than obtainment) of multiple ES was mainly situated in the northern part of Mengyin County. Overall, the current state of multiple ES across Mengyin County is classified as "Endangered" classification according to application of threat categorization framework. It is necessary to restructure and manage socioeconomic factors for multiple ES. At national level, the macro decision-making (controlling population density) and the mechanisms (attracting high-quality human resources into the rural) will play an important role in promoting multiple ES management, and it is necessary to provide 3 or more years of tailored educational resources for rural residents to advance multiple ES in agricultural landscape. Development of agricultural PES programs in China that enable farmers to profit from production ES is a sustainable strategy for increasing

Unhealthy interactions: the role of stereotype threat in health disparities.

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Aronson, Joshua; Burgess, Diana; Phelan, Sean M; Juarez, Lindsay

2013-01-01

Stereotype threat is the unpleasant psychological experience of confronting negative stereotypes about race, ethnicity, gender, sexual orientation, or social status. Hundreds of published studies show how the experience of stereotype threat can impair intellectual functioning and interfere with test and school performance. Numerous published interventions derived from this research have improved the performance and motivation of individuals targeted by low-ability stereotypes. Stereotype threat theory and research provide a useful lens for understanding and reducing the negative health consequences of interracial interactions for African Americans and members of similarly stigmatized minority groups. Here we summarize the educational outcomes of stereotype threat and examine the implications of stereotype threat for health and health-related behaviors.

Research on classification of nuclear and radiological accident from IAEA threat category with estimation of INES scale

Energy Technology Data Exchange (ETDEWEB)

Cha, Seok Ki [Dept. of Nuclear engineering, Univ of SeJong, Seoul (Korea, Republic of); Kim, Siu [Korea Nuclear International Cooperation Foundation, Daejeon (Korea, Republic of)

2017-04-15

As there is increasing use of nuclear energy and radiation while information on nuclear related accidents are accumulated, international interest in nuclear and radiation incidents is increasing rapidly. Because of the specificity of nuclear energy and radiation, the damage caused by such accidents will be spread to the larger area around the accident point due to the radiation and cause biological damage and mental-psychological damage. The purpose of this study is to categorize historical incidents using the Threat Category concept described in the publication of IAEA Safety Guide GS-G-2.1. In addition to categorizing actual events and accidents into Threat Categories, causes of occurrences, the type of radioactive source which leads to the main threats, the type of radiation exposure, and the type of patient are organized in detail. As a result of the analysis of representative historical cases, most accident cases caused by 'Nuclear Energy-Related Business Operator' correspond to 1 (Anomaly) ~ 4 (Accident with Local Consequences) in the INES Scale by IAEA. From the some accident cases, while the radiological damage can be seen to be local, but it can be seen that the possibility of 6 (Serious Accident) can not be absolutely excluded.

Unleashing Latent Ability: Implications of Stereotype Threat for College Admissions

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Logel, Christine R.; Walton, Gregory M.; Spencer, Steven J.; Peach, Jennifer; Mark, Zanna P.

2012-01-01

Social-psychological research conducted over the past 15 years provides compelling evidence that pervasive psychological threats are present in common academic environments--especially threats that originate in negative intellectual stereotypes--and that these threats undermine the real-world academic performance of non-Asian ethnic minority…

Protected areas in tropical Africa: assessing threats and conservation activities.

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Tranquilli, Sandra; Abedi-Lartey, Michael; Abernethy, Katharine; Amsini, Fidèle; Asamoah, Augustus; Balangtaa, Cletus; Blake, Stephen; Bouanga, Estelle; Breuer, Thomas; Brncic, Terry M; Campbell, Geneviève; Chancellor, Rebecca; Chapman, Colin A; Davenport, Tim R B; Dunn, Andrew; Dupain, Jef; Ekobo, Atanga; Eno-Nku, Manasseh; Etoga, Gilles; Furuichi, Takeshi; Gatti, Sylvain; Ghiurghi, Andrea; Hashimoto, Chie; Hart, John A; Head, Josephine; Hega, Martin; Herbinger, Ilka; Hicks, Thurston C; Holbech, Lars H; Huijbregts, Bas; Kühl, Hjalmar S; Imong, Inaoyom; Yeno, Stephane Le-Duc; Linder, Joshua; Marshall, Phil; Lero, Peter Minasoma; Morgan, David; Mubalama, Leonard; N'Goran, Paul K; Nicholas, Aaron; Nixon, Stuart; Normand, Emmanuelle; Nziguyimpa, Leonidas; Nzooh-Dongmo, Zacharie; Ofori-Amanfo, Richard; Ogunjemite, Babafemi G; Petre, Charles-Albert; Rainey, Hugo J; Regnaut, Sebastien; Robinson, Orume; Rundus, Aaron; Sanz, Crickette M; Okon, David Tiku; Todd, Angelique; Warren, Ymke; Sommer, Volker

2014-01-01

Numerous protected areas (PAs) have been created in Africa to safeguard wildlife and other natural resources. However, significant threats from anthropogenic activities and decline of wildlife populations persist, while conservation efforts in most PAs are still minimal. We assessed the impact level of the most common threats to wildlife within PAs in tropical Africa and the relationship of conservation activities with threat impact level. We collated data on 98 PAs with tropical forest cover from 15 countries across West, Central and East Africa. For this, we assembled information about local threats as well as conservation activities from published and unpublished literature, and questionnaires sent to long-term field workers. We constructed general linear models to test the significance of specific conservation activities in relation to the threat impact level. Subsistence and commercial hunting were identified as the most common direct threats to wildlife and found to be most prevalent in West and Central Africa. Agriculture and logging represented the most common indirect threats, and were most prevalent in West Africa. We found that the long-term presence of conservation activities (such as law enforcement, research and tourism) was associated with lower threat impact levels. Our results highlight deficiencies in the management effectiveness of several PAs across tropical Africa, and conclude that PA management should invest more into conservation activities with long-term duration.

Hindrances are not threats: advancing the multidimensionality of work stress.

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Tuckey, Michelle R; Searle, Ben J; Boyd, Carolyn M; Winefield, Anthony H; Winefield, Helen R

2015-04-01

The challenge-hindrance framework has proved useful for explaining inconsistencies in relationships between work stressors and important outcomes. By introducing the distinction between threat and hindrance to this framework, we capture the potential for personal harm or loss (threat) associated with stressors, as distinct from the potential to block goal attainment (hindrance) or promote gain (challenge). In Study 1, survey data were collected from 609 retail workers, 220 of whom responded 6 months later. The results supported a 3-factor threat-hindrance-challenge stressor structure and showed that threat stressors are associated with increased psychological distress and emotional exhaustion, and reduced dedication, whereas hindrance stressors undermine dedication but may not be related to distress or exhaustion with threats included in the model. Study 2 utilized a diary study design, with data collected from 207 workers over 3 workdays. Findings revealed that the threat, hindrance, and challenge appraisals of individual workers are statistically distinct, and associated with stressors and well-being as anticipated: threats with role conflict and anxiety, hindrances with organizational constraints and fatigue, and challenges with skill demands and enthusiasm. Overall, moving to a 3-dimensional challenge-hindrance-threat framework for stressors and stress appraisals will support a more accurate picture regarding the nature, processes, and effects of stressors on individuals and organizations, and ensure prevention efforts are not misguided. (c) 2015 APA, all rights reserved).

Protected areas in tropical Africa: assessing threats and conservation activities.

Directory of Open Access Journals (Sweden)

Sandra Tranquilli

Full Text Available Numerous protected areas (PAs have been created in Africa to safeguard wildlife and other natural resources. However, significant threats from anthropogenic activities and decline of wildlife populations persist, while conservation efforts in most PAs are still minimal. We assessed the impact level of the most common threats to wildlife within PAs in tropical Africa and the relationship of conservation activities with threat impact level. We collated data on 98 PAs with tropical forest cover from 15 countries across West, Central and East Africa. For this, we assembled information about local threats as well as conservation activities from published and unpublished literature, and questionnaires sent to long-term field workers. We constructed general linear models to test the significance of specific conservation activities in relation to the threat impact level. Subsistence and commercial hunting were identified as the most common direct threats to wildlife and found to be most prevalent in West and Central Africa. Agriculture and logging represented the most common indirect threats, and were most prevalent in West Africa. We found that the long-term presence of conservation activities (such as law enforcement, research and tourism was associated with lower threat impact levels. Our results highlight deficiencies in the management effectiveness of several PAs across tropical Africa, and conclude that PA management should invest more into conservation activities with long-term duration.

Use of modified threat reduction assessments to estimate success of conservation measures within and adjacent to Kruger National Park, South Africa.

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Anthony, Brandon P

2008-12-01

The importance of biodiversity as natural capital for economic development and sustaining human welfare is well documented. Nevertheless, resource degradation rates and persistent deterioration of human welfare in developing countries is increasingly worrisome. Developing effective monitoring and evaluation schemes and measuring biodiversity loss continue to pose unique challenges, particularly when there is a paucity of historical data. Threat reduction assessment (TRA) has been proposed as a method to measure conservation success and as a proxy measurement of conservation impact, monitoring threats to resources rather than changes to biological parameters themselves. This tool is considered a quick, practical alternative to more cost- and time-intensive approaches, but has inherent weaknesses. I conducted TRAs to evaluate the effectiveness of Kruger National Park (KNP) and Limpopo Province, South Africa, in mitigating threats to biodiversity from 1994 to 2004 in 4 geographical areas. I calculated TRA index values in these TRAs by using the original scoring developed by Margoluis and Salafsky (2001)and a modified scoring system that assigned negative mitigation values to incorporate new or worsening threats. Threats were standardized to allow comparisons across the sites. Modified TRA index values were significantly lower than values derived from the original scoring exercise. Five of the 11 standardized threats were present in all 4 assessment areas, 2 were restricted to KNP, 2 to Limpopo Province, and 2 only to Malamulele municipality. These results indicate, first, the need to integrate negative mitigation values into TRA scoring. By including negative values, investigators will be afforded a more accurate picture of biodiversity threats and of temporal and spatial trends across sites. Where the original TRA scoring was used to measure conservation success, reevaluation of these cases with the modified scoring is recommended. Second, practitioners must

Interrelationships Among Men’s Threat Potential, Facial Dominance, and Vocal Dominance

Directory of Open Access Journals (Sweden)

Chengyang Han

2017-03-01

Full Text Available The benefits of minimizing the costs of engaging in violent conflict are thought to have shaped adaptations for the rapid assessment of others’ capacity to inflict physical harm. Although studies have suggested that men’s faces and voices both contain information about their threat potential, one recent study suggested that men’s faces are a more valid cue of their threat potential than their voices are. Consequently, the current study investigated the interrelationships among a composite measure of men’s actual threat potential (derived from the measures of their upper-body strength, height, and weight and composite measures of these men’s perceived facial and vocal threat potential (derived from dominance, strength, and weight ratings of their faces and voices, respectively. Although men’s perceived facial and vocal threat potential were positively correlated, men’s actual threat potential was related to their perceived facial, but not vocal, threat potential. These results present new evidence that men’s faces may be a more valid cue of these aspects of threat potential than their voices are.

Functional effectiveness of threat appeals in exercise promotion messages

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Olivier Mairesse

2010-01-01

Full Text Available As more than 70% of individuals in Western societies can be categorized as sedentary and inactivity has been recognized to lead to a series of serious physical and psychological disorders, the importance of physical activity promotion is ever more emphasized. Many social marketing campaigns use threat (or fear appeals to promote healthy behaviors. Theoretical models, such as the Extended Parallel Process Model integrate concepts as 'perceived threat' and 'perceived efficacy' to explain how such messages operate and can cause diverse behavioral reactions. It is however still not entirely clear how these different aspects are valuated and combined to determine desired versus undesired response behaviors in individuals. In a functional integration task, threat-appeal based exercise promotion messages varying in psychological threat and efficacy content were shown to sedentary employees in order to assess how they affect their intention to engage in physical exercise. Our results show that individuals can be categorized in 4 different clusters depending on the way they valuate threat and efficacy appeals: i.e. individuals sensitive to both types of cues, those sensitive to either the threat or the efficacy component in the message and those insensitive to either one of them. As different segments of receivers of the message react differently to threat and efficacy combinations, it is concluded that different approaches to designing effective mass media campaigns may be required for effective exercise promotion.

Architectural model for crowdsourcing for human security threats ...

African Journals Online (AJOL)

Journal of Computer Science and Its Application ... Crowdsourcing for Human Security Threats Situation Information and Response System (CHSTSIRS) is proposed in this paper to report Human Security (HS) ... Keywords: Human security, Crowdsourcing, Threats, Situation Information, Agency, Google, Cloud Messaging ...

Gender Gaps in Achievement and Participation in Multiple Introductory Biology Classrooms

Science.gov (United States)

Brownell, Sara E.; Wenderoth, Mary Pat

2014-01-01

Although gender gaps have been a major concern in male-dominated science, technology, engineering, and mathematics disciplines such as physics and engineering, the numerical dominance of female students in biology has supported the assumption that gender disparities do not exist at the undergraduate level in life sciences. Using data from 23 large introductory biology classes for majors, we examine two measures of gender disparity in biology: academic achievement and participation in whole-class discussions. We found that females consistently underperform on exams compared with males with similar overall college grade point averages. In addition, although females on average represent 60% of the students in these courses, their voices make up less than 40% of those heard responding to instructor-posed questions to the class, one of the most common ways of engaging students in large lectures. Based on these data, we propose that, despite numerical dominance of females, gender disparities remain an issue in introductory biology classrooms. For student retention and achievement in biology to be truly merit based, we need to develop strategies to equalize the opportunities for students of different genders to practice the skills they need to excel. PMID:25185231

Environmental metabolomics: a SWOT analysis (strengths, weaknesses, opportunities, and threats).

Science.gov (United States)

Miller, Marion G

2007-02-01

Metabolomic approaches have the potential to make an exceptional contribution to understanding how chemicals and other environmental stressors can affect both human and environmental health. However, the application of metabolomics to environmental exposures, although getting underway, has not yet been extensively explored. This review will use a SWOT analysis model to discuss some of the strengths, weaknesses, opportunities, and threats that are apparent to an investigator venturing into this relatively new field. SWOT has been used extensively in business settings to uncover new outlooks and identify problems that would impede progress. The field of environmental metabolomics provides great opportunities for discovery, and this is recognized by a high level of interest in potential applications. However, understanding the biological consequence of environmental exposures can be confounded by inter- and intra-individual differences. Metabolomic profiles can yield a plethora of data, the interpretation of which is complex and still being evaluated and researched. The development of the field will depend on the availability of technologies for data handling and that permit ready access metabolomic databases. Understanding the relevance of metabolomic endpoints to organism health vs adaptation vs variation is an important step in understanding what constitutes a substantive environmental threat. Metabolomic applications in reproductive research are discussed. Overall, the development of a comprehensive mechanistic-based interpretation of metabolomic changes offers the possibility of providing information that will significantly contribute to the protection of human health and the environment.

Himalayan Vultures in Khodpe, far-west Nepal: is there any threat?

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Manoj Kumar Joshi

2015-11-01

Full Text Available There is evidence that Himalayan Vulture Gyps himalayensis is susceptible to the veterinary drug diclofenac, which is responsible for the decline of other Gyps species across South Asia.  Unlike other Gyps species, there is little quantitative data to assess Himalayan Vultures population.  Based on observation, we analyzed the flock size and breeding success of the Himalayan Vultures on two cliffs of Khodpe in Baitadi District, far-west Nepal.  The mean flock size of Himalayan Vulture was 25.83±6.33.  Overall breeding success was 90.9% based on active nests.  We also conducted a questionnaire survey to assess the perceived threats in the view of local people to vultures and these threats include loss of food, veterinary drug, lack of proper nest sites, and lack of public awareness.  Additionally, 76% of the respondents felt that vultures were decreasing in the area, 94.7% were not aware of the toxicity of diclofenac to vultures, and very few (2% knew about the availability of meloxicam as a safe alternative drug.  The colony we studied is one of the few remaining known breeding populations, which provide baseline information from far-west Nepal, thus we recommend for conservation and continuous monitoring of this species to understand their population change and breeding biology. 

Kidnapping and abduction minimizing the threat and lessons in survival

CERN Document Server

Heard, Brian John

2014-01-01

Terrorist groups and organized crime cartels pose an increasing threat of kidnapping throughout many regions in the word. At the same time, international travel has become more commonplace for both business and leisure purposes. Kidnapping and Abduction: Minimizing the Threat and Lessons in Survival provides a practical guide on the precautions travelers can take to avoid being kidnapped or derail a kidnapping attempt in progress. In the event this cannot be avoided, the book supplies advice on how to ensure survival during captivity. Readers will learn: The basic elements of kidnapping and abduction The motivations and mechanisms of kidnappers The hotspots where kidnapping/hostage taking is prevalent Vehicles best suited for avoidance of kidnap threat and proposals for up-armoring an existing vehicle How to recognize immediate threats and precautions to be taken in assessing threat level The types of weapons most favored by kidnappers and their threat level Available bullet-resistant materials and their use ...

The Bright Side of Threatened Narcissism: Improved Performance Following Ego Threat.

Science.gov (United States)

Nevicka, Barbora; Baas, Matthijs; Ten Velden, Femke S

2016-12-01

Narcissistic individuals have highly positive self-views and overestimate their abilities. Consequently, they tend to react aggressively whenever they receive information that does not match their high self-views (ego threat). We argue that focusing on aggression merely portrays a one-sided view of narcissistic individuals and the manner in which they counter ego threats. We propose that following ego threat, narcissism can also fuel performance. In four studies, we measured nonclinical narcissism and allocated Dutch undergraduate university students (N 1  = 175, N 2  = 142, N 3  = 159, N 4  = 174) to either an ego threat or a no ego threat condition. Ego threat involved negative feedback (Studies 1-2) or threat to uniqueness (Studies 3-4). We measured participants' intentions to complete a challenging task (Study 1), their creative performance (Studies 2-3), and their performance on an anagram task (Study 4). Across Studies 1-3, we consistently found that following ego threat, higher nonclinical narcissism was associated with greater willingness to perform tasks that enabled demonstration of abilities and enhanced creative performance. These results were confirmed using a meta-analysis. However, anagram performance was not enhanced following ego threat. We provide additional analyses that might help explain this. Our findings thus reveal a more positive side to the way narcissistic individuals manage threats to their self-image. © 2015 Wiley Periodicals, Inc.

Personality, threat and affective responses to cultural diversity

NARCIS (Netherlands)

Van der Zee, K.I.; Van Der Gang, Ineke

The present study tried to reconcile assumptions from Terror Management Theory that individual differences in openness to diversity are enhanced by existential threat with own recent findings suggesting that individual differences are diminished by threat. A model was supported assuming that it is

An Examination of Stereotype Threat Effects on Girls' Mathematics Performance

Science.gov (United States)

Ganley, Colleen M.; Mingle, Leigh A.; Ryan, Allison M.; Ryan, Katherine; Vasilyeva, Marina; Perry, Michelle

2013-01-01

Stereotype threat has been proposed as 1 potential explanation for the gender difference in standardized mathematics test performance among high-performing students. At present, it is not entirely clear how susceptibility to stereotype threat develops, as empirical evidence for stereotype threat effects across the school years is inconsistent. In…

Cognitive and affective components of challenge and threat states.

Science.gov (United States)

Meijen, Carla; Jones, Marc V; McCarthy, Paul J; Sheffield, David; Allen, Mark S

2013-01-01

We explored the cognitive and affective components of the Theory of Challenge and Threat States in Athletes (TCTSA) using a cross-sectional design. One hundred and seventy-seven collegiate athletes indicated how they typically approached an important competition on measures of self-efficacy, perceived control, achievement goals, emotional states and interpretation of emotional states. Participants also indicated to what extent they typically perceived the important competition as a challenge and/or a threat. The results suggest that a perception of challenge was not predicted by any of the cognitive components. A perception of threat was positively predicted by avoidance goals and negatively predicted by self-efficacy and approach goals. Both challenge and threat had a positive relationship with anxiety. Practical implications of this study are that an avoidance orientation appeared to be related to potentially negative constructs such as anxiety, threat and dejection. The findings may suggest that practitioners and researchers should focus on reducing an avoidance orientation, however the results should be treated with caution in applied settings, as this study did not examine how the combination of constructs exactly influences sport performance. The results provided partial support for the TCTSA with stronger support for proposed relationships with threat rather than challenge states.

The Effects of Urban Sprawl on Birds at Multiple Levels of Biological Organization

Directory of Open Access Journals (Sweden)

Robert Blair

2004-12-01

Full Text Available Urban sprawl affects the environment in myriad ways and at multiple levels of biological organization. In this paper I explore the effects of sprawl on native bird communities by comparing the occurrence of birds along gradients of urban land use in southwestern Ohio and northern California and by examining patterns at the individual, species, community, landscape, and continental levels. I do this by assessing the distribution and abundance of all bird species occupying sites of differing land-use intensity in Ohio and California. Additionally, I conducted predation experiments using artificial nests, tracked the nest fate of American Robins and Northern Cardinals, and assessed land cover in these sites. At the individual level, predation on artificial nests decreased with urbanization; however, this trend was not reflected in the nesting success of robins and cardinals, which did not increase with urbanization. At the species level, sprawl affected local patterns of extinction and invasion; the density of different species peaked at different levels of urbanization. At the community level, species richness and diversity peaked at moderate levels of urbanization, and the number of low-nesting species and of species with multiple broods increased with urbanization. The community-level results may reflect both the species-level patterns of local extinction and invasion as well as broader landscape-level patterns. At the landscape level, a linear combination of spatial heterogeneity and density of woody patches accurately predicted both species richness and Shannon Diversity. At the continental level, local extinction of endemic species, followed by the invasion of ubiquitous weedy species, leads to faunal homogenization between ecoregions.

9 CFR 112.6 - Packaging biological products.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Packaging biological products. 112.6... AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS PACKAGING AND LABELING § 112.6 Packaging biological products. (a) Each multiple-dose final container of a biological product...

Hope, connectedness, and action: responses of adolescents and young adults to the threat of nuclear war

Energy Technology Data Exchange (ETDEWEB)

Fernald, M.C.

1985-01-01

This study undertook to assess the degree to which a person's sense of interconnectedness with others may have a mediating effect on whether one reacts to the consciousness of nuclear threat with feelings of despair (helplessness and hopelessness) or with a sense of empowerment (hope, efficacy, and action for change). Subjects included 119 public high school students and 14 Friends' school students, ranging from 12-18 years of age; 58 university students ranging from 18-25 years of age; and 24 parents of public school students, 10 adult Friends, and 38 members of Physicians for Social Responsibility, ranging from 20-83 years of age. A self-rating questionnaire was administered to assess subjects' conscious level of concern about nuclear issues, feelings of connectedness with others in general and about nuclear concerns, feelings of hope and efficacy in general and with regard to nuclear issues, and participation in activities reflecting concerns about nuclear threat. Correlational analyses (multiple regression, Spearman Rho, Kendall's Tau) showed that general feelings of hope, level of activity, and feelings of connectedness about nuclear concerns were the best predictors of hope about nuclear concerns. Conscious level of concern and feelings of connectedness about nuclear concerns, along with age and SES were the best predictors of an active response to nuclear threat; additionally, parents' level of concern about nuclear issues was predictive of their children's degree of activity in response to nuclear threat. Adolescents' level of concern and degree of connectedness with others was predicted by their parents' degree of connectedness.

Examining the Effects of Stereotype Threat on Test-Taking Behaviors

Science.gov (United States)

Scherbaum, Charles A.; Blanshetyn, Victoria; Marshall-Wolp, Elizabeth; McCue, Elizabeth; Strauss, Ross

2011-01-01

This study examines the relationship between stereotype threat and individual test-taking behaviors. Previous research has examined the impact of stereotype threat on test scores, but little research has examined the impact of stereotype threat on the test-taking behaviors impacting those scores. Using a pre-post experimental design, stereotype…

Threat and efficacy in Malaysia’s cancer news coverage

Directory of Open Access Journals (Sweden)

Collin Jerome

2017-12-01

Full Text Available Background: The news media plays important roles not only in creating and disseminating health messages, but also in influencing people’s perceptions of health and their health behaviours. However, much more needs to be known about the creation process, particularly how health messages are created with the goal of raising awareness and knowledge, and changing people’s attitudes and behaviours. This paper presents a study aimed at examining cancer risk messages in Malaysia’s leading newspapers. Methods: Our search identified count the total 73 articles related to cancer which were published in three leading Malaysian English dailies in 2012 – September 2017. Of these, 10 were selected for a content analysis using the Extended Parallel Process (EPPM Model. The analysis focused on the presence and the levels of two important components required for designing effective health risk message: threat (severity and susceptibility and efficacy (responses efficacy and self-efficacy. The language used in the news articles was also analysed to see whether it helped enhance the threat-efficacy levels which are crucial for increasing message acceptance and yielding behaviour change. Results: Present study shows that the varying presence of threat and efficacy in the articles as evidenced by messages that focused on threat alone with no efficacy and messages that highlighted both threat and efficacy. Results also show contrasting levels of threat and efficacy as evidenced by messages that possessed high levels of threat and efficacy and messages that revealed a high level of threat and a low level of efficacy. Furthermore, the contents were composed differently in terms of language use: some articles used neutral language while others used vivid and descriptive language in addressing the topic and target audience. These have implication on message acceptance and behaviour change where high levels of threat and efficacy, and the ways in which vivid

The implications of non-linear biological oscillations on human electrophysiology for electrohypersensitivity (EHS) and multiple chemical sensitivity (MCS).

Science.gov (United States)

Sage, Cindy

2015-01-01

The 'informational content' of Earth's electromagnetic signaling is like a set of operating instructions for human life. These environmental cues are dynamic and involve exquisitely low inputs (intensities) of critical frequencies with which all life on Earth evolved. Circadian and other temporal biological rhythms depend on these fluctuating electromagnetic inputs to direct gene expression, cell communication and metabolism, neural development, brainwave activity, neural synchrony, a diversity of immune functions, sleep and wake cycles, behavior and cognition. Oscillation is also a universal phenomenon, and biological systems of the heart, brain and gut are dependent on the cooperative actions of cells that function according to principles of non-linear, coupled biological oscillations for their synchrony. They are dependent on exquisitely timed cues from the environment at vanishingly small levels. Altered 'informational content' of environmental cues can swamp natural electromagnetic cues and result in dysregulation of normal biological rhythms that direct growth, development, metabolism and repair mechanisms. Pulsed electromagnetic fields (PEMF) and radiofrequency radiation (RFR) can have the devastating biological effects of disrupting homeostasis and desynchronizing normal biological rhythms that maintain health. Non-linear, weak field biological oscillations govern body electrophysiology, organize cell and tissue functions and maintain organ systems. Artificial bioelectrical interference can give false information (disruptive signaling) sufficient to affect critical pacemaker cells (of the heart, gut and brain) and desynchronize functions of these important cells that orchestrate function and maintain health. Chronic physiological stress undermines homeostasis whether it is chemically induced or electromagnetically induced (or both exposures are simultaneous contributors). This can eventually break down adaptive biological responses critical to health

Cave invertebrates in Espírito Santo state, Brazil: a primary analysis of endemism, threats and conservation priorities

Directory of Open Access Journals (Sweden)

Marconi Souza Silva

2015-08-01

Full Text Available The cave-dwelling invertebrates were studied according to their composition, biodiversity, distribution and threats in the Atlantic Forest Central Biodiversity Corridor, a priority area for conservation actions in Brazil. Twelve obligate cave species were found, plus 495 troglophile species. Araneae (103 spp., Coleoptera (61 spp., Diptera (56 spp. and Lepidoptera (38 spp. were the richest taxa. The richness was higher in the carbonate caves (63 spp., sd = 16.7 and the highest diversity in granitic caves (H´= 2.68, sd = 0.5. The spatial turnover was 63.45 and similarity less than 30%. The total richness was correlated with the linear extension of the caves (Rs = 0.757, p ≤ 0.05. Surrounding area deforestation and religious and tourist use were the main threats. Emergency attention is recommended regarding protective actions, management and conservation of caves of extremely high biological importance.

Towards an Enhancement of Organizational Information Security through Threat Factor Profiling (TFP) Model

Science.gov (United States)

Sidi, Fatimah; Daud, Maslina; Ahmad, Sabariah; Zainuddin, Naqliyah; Anneisa Abdullah, Syafiqa; Jabar, Marzanah A.; Suriani Affendey, Lilly; Ishak, Iskandar; Sharef, Nurfadhlina Mohd; Zolkepli, Maslina; Nur Majdina Nordin, Fatin; Amat Sejani, Hashimah; Ramadzan Hairani, Saiful

2017-09-01

Information security has been identified by organizations as part of internal operations that need to be well implemented and protected. This is because each day the organizations face a high probability of increase of threats to their networks and services that will lead to information security issues. Thus, effective information security management is required in order to protect their information assets. Threat profiling is a method that can be used by an organization to address the security challenges. Threat profiling allows analysts to understand and organize intelligent information related to threat groups. This paper presents a comparative analysis that was conducted to study the existing threat profiling models. It was found that existing threat models were constructed based on specific objectives, thus each model is limited to only certain components or factors such as assets, threat sources, countermeasures, threat agents, threat outcomes and threat actors. It is suggested that threat profiling can be improved by the combination of components found in each existing threat profiling model/framework. The proposed model can be used by an organization in executing a proactive approach to incident management.

Detection of biological warfare agents using ultra violet-laser induced fluorescence LIDAR.

Science.gov (United States)

Joshi, Deepti; Kumar, Deepak; Maini, Anil K; Sharma, Ramesh C

2013-08-01

This review has been written to highlight the threat of biological warfare agents, their types and detection. Bacterial biological agent Bacillus anthracis (bacteria causing the disease anthrax) which is most likely to be employed in biological warfare is being discussed in detail. Standoff detection of biological warfare agents in aerosol form using Ultra violet-Laser Induced Fluorescence (UV-LIF) spectroscopy method has been studied. Range-resolved detection and identification of biological aerosols by both nano-second and non-linear femto-second LIDAR is also discussed. Calculated received fluorescence signal for a cloud of typical biological agent Bacillus globigii (Simulants of B. anthracis) at a location of ~5.0 km at different concentrations in presence of solar background radiation has been described. Overview of current research efforts in internationally available working UV-LIF LIDAR systems are also mentioned briefly. Copyright © 2013 Elsevier B.V. All rights reserved.

Beyond the Dirty Dozen: A Proposed Methodology for Assessing Future Bioweapon Threats.

Science.gov (United States)

Cieslak, Theodore J; Kortepeter, Mark G; Wojtyk, Ronald J; Jansen, Hugo-Jan; Reyes, Ricardo A; Smith, James O

2018-01-01

Countermeasure Availability, and Ease of Detection. Reproducibility of scoring data was assessed by examining the standard deviations (SD) of mean scores. Our results were unexpected. Several familiar biothreat diseases such as anthrax and tularemia were judged, by our experts, to be less threatening than many others owing to a number of factors including ease of detection, lack of communicability, and the ready availability of countermeasures. Conversely, several toxins were judged by experts to have very high potential as threat agents owing, in part, to their reliability, virulence, and a lack of available countermeasures. Agreement among experts, as determined by lower SD about a mean score, was greater for more familiar threats. Our study was designed to provide a concise and east-to-apply set of criteria that could be used by NATO nations to evaluate emerging infectious disease threats with respect to their weaponization potential. Our results were unexpected. We believe that a lack of appropriate weighting factors may explain these results and suggest that future studies weigh each of the 12 proposed criteria based on the intended use of the assessment data and other situational factors. We believe that the greatest value of our study lies in a codification of the attributes of a biological weapon. © Association of Military Surgeons of the United States 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

A Probabilistic Analysis Framework for Malicious Insider Threats

DEFF Research Database (Denmark)

Chen, Taolue; Kammuller, Florian; Nemli, Ibrahim

2015-01-01

Malicious insider threats are difficult to detect and to mitigate. Many approaches for explaining behaviour exist, but there is little work to relate them to formal approaches to insider threat detection. In this work we present a general formal framework to perform analysis for malicious insider...

Investigating Hypervigilance for Social Threat of Lonely Children

Science.gov (United States)

Qualter, Pamela; Rotenberg, Ken; Barrett, Louise; Henzi, Peter; Barlow, Alexandra; Stylianou, Maria; Harris, Rebecca A.

2013-01-01

The hypothesis that lonely children show hypervigilance for social threat was examined in a series of three studies that employed different methods including advanced eye-tracking technology. Hypervigilance for social threat was operationalized as hostility to ambiguously motivated social exclusion in a variation of the hostile attribution…

Towards Formal Analysis of Insider Threats for Auctions

DEFF Research Database (Denmark)

Kammueller, Florian; Kerber, Manfred; Probst, Christian W.

2016-01-01

is meaningful to prove correctness and scrutinize vulnerability to security and privacy attacks. Surveying the threats in auctions and insider collusions, we present an approach to model and analyze auction protocols for insider threats using the interactive theorem prover Isabelle. As a case study, we use...

SECURITY THREATS IN CENTRAL ASIA

Directory of Open Access Journals (Sweden)

Çağla Gül Yesevi

2013-07-01

Full Text Available This study will analyze main security threats in Central Asia. It is obvious thatsince the end of Cold War, there have been many security threats in Central Asiaas internal weakness of Central Asian states, terrorism, transnational crime,economic insecurity, environmental issues, drug trafficking, ethnic violence,regional instability. This study will propose thatwith increasing interdependence,states need each other to solve these global security problems. In that sense,regional and sub-regional cooperation between Central Asian states and with otherregional actors has been witnessed. It is clear that the withdrawal of NATO fromAfghanistan will destabilize Central Asia. This study will investigate overallsecurity situation in Central Asia and affects andcontributions of regionalorganizations to Eurasian security

Solutions to the new threats to academic freedom?

Science.gov (United States)

Tooley, Michael

2014-05-01

In my commentary on Francesca Minerva's article 'New Threats to Academic Freedom', I agree with her contention that the existence of the Internet has given rise to new and very serious threats to academic freedom. I think that it is crucial that we confront those threats, and find ways to eliminate them, which I believe can be done. The threats in question involve both authors and editors. In the case of authors, I argue that the best solution is not anonymous publication, but publication using pseudonyms, and I describe how that would work. In the case of editors, my proposal is a website that a number of journals would have access to, where papers that editors judge to be clearly worthy of publication, but whose publication seems likely to set off a firestorm of public and media protest, could be published without any indication of the journal that had accepted the paper for publication. © 2014 John Wiley & Sons Ltd.

Prefrontal inhibition of threat processing protects working memory from interference.

Directory of Open Access Journals (Sweden)

Robert James Clarke

2013-05-01

Full Text Available Bottom-up processes can interrupt ongoing cognitive processing in order to adaptively respond to emotional stimuli of high potential significance, such as those that threaten wellbeing. However it is vital that this interference can be modulated in certain contexts to focus on current tasks. Deficits in the ability to maintain the appropriate balance between cognitive and emotional demands can severely impact on day-to-day activities. This fMRI study examined this interaction between threat processing and cognition; 18 adult participants performed a visuospatial working memory (WM task with two load conditions, in the presence and absence of anxiety induction by threat of electric shock. Threat of shock interfered with performance in the low cognitive load condition; however interference was eradicated under high load, consistent with engagement of emotion regulation mechanisms. Under low load the amygdala showed significant activation to threat of shock that was modulated by high cognitive load. A directed top-down control contrast identified two regions associated with top-down control; ventrolateral PFC and dorsal ACC. Dynamic causal modelling provided further evidence that under high cognitive load, top-down inhibition is exerted on the amygdala and its outputs to prefrontal regions. Additionally, we hypothesised that individual differences in a separate, non-emotional top-down control task would predict the recruitment of dorsal ACC and ventrolateral PFC during top-down control of threat. Consistent with this, performance on a separate dichotic listening task predicted dorsal ACC and ventrolateral PFC activation during high WM load under threat of shock, though activation in these regions did not directly correlate with WM performance. Together, the findings suggest that under high cognitive load and threat, top-down control is exerted by dACC and vlPFC to inhibit threat processing, thus enabling WM performance without threat

The threats

International Nuclear Information System (INIS)

Brunel, S.; Touchard, P.; Ferrandery, J.L.

2005-01-01

Second chapter of the book on the geopolitics of the sustainable development, this chapter deals with the threats of the climatic change on the earth and the humans. the authors analyze the consequences of the climatic change on the developing countries of the South and the necessity of a sustainable development implementation in the North. They inform on the resources depletion, the water problem, the nuclear activities and the public health and the french government policy facing the sustainable management of the territory. (A.L.B.)

Bio-Terrorism Threat and Casualty Prevention

Energy Technology Data Exchange (ETDEWEB)

NOEL,WILLIAM P.

2000-01-01

The bio-terrorism threat has become the ''poor man's'' nuclear weapon. The ease of manufacture and dissemination has allowed an organization with only rudimentary skills and equipment to pose a significant threat with high consequences. This report will analyze some of the most likely agents that would be used, the ease of manufacture, the ease of dissemination and what characteristics of the public health response that are particularly important to the successful characterization of a high consequence event to prevent excessive causalities.

Adrenocortical responses to offspring-directed threats in two open-nesting birds.

Science.gov (United States)

Butler, Luke K; Bisson, Isabelle-Anne; Hayden, Timothy J; Wikelski, Martin; Romero, L Michael

2009-07-01

Dependent young are often easy targets for predators, so for many parent vertebrates, responding to offspring-directed threats is a fundamental part of reproduction. We tested the parental adrenocortical response of the endangered black-capped vireo (Vireo atricapilla) and the common white-eyed vireo (V. griseus) to acute and chronic threats to their offspring. Like many open-nesting birds, our study species experience high offspring mortality. Parents responded behaviorally to a predator decoy or human 1-2m from their nests, but, in contrast to similar studies of cavity-nesting birds, neither these acute threats nor chronic offspring-directed threats altered plasma corticosterone concentrations of parents. Although parents in this study showed no corticosterone response to offspring-directed threats, they always increased corticosterone concentrations in response to capture. To explain these results, we propose that parents perceive their risk of nest-associated death differently depending on nest type, with cavity-nesting adults perceiving greater risk to themselves than open-nesters that can readily detect and escape from offspring-directed threats. Our results agree with previous studies suggesting that the hypothalamic-pituitary-adrenal axis, a major physiological mechanism for coping with threats to survival, probably plays no role in coping with threats to offspring when risks to parents and offspring are not correlated. We extend that paradigm by demonstrating that nest style may influence how adults perceive the correlation between offspring-directed and self-directed threats.

Advanced insider threat mitigation workshop instructional materials

Energy Technology Data Exchange (ETDEWEB)

Gibbs, Philip [Brookhaven National Lab. (BNL), Upton, NY (United States); Larsen, Robert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); O Brien, Mike [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Edmunds, Tom [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2008-11-01

Insiders represent a formidable threat to nuclear facilities. This set of workshop materials covers methodologies to analyze and approaches to mitigate the threat of an insider attempting abrupt and protracted theft of nuclear materials. This particular set of materials is a n update of a January 2008 version to add increased emphasis on Material Control and Accounting and its role with respect to protracted insider nuclear material theft scenarios.

A Model for Situation and Threat Assessment

Science.gov (United States)

2006-12-01

CUBRC , Inc.) 8151 Needwood #T103 Derwood, MD 20855 UNITED STATES steinberg@cubrc.org A model is presented for situation and threat assessment...PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Subject Matter Expert (SME) Calspan-UB Research Center ( CUBRC , Inc.) 8151 Needwood #T103 Derwood, MD...1 A Model for Situation and Threat Assessment Alan Steinberg CUBRC , Inc. steinberg@cubrc.org November, 2005 2 Objectives • Advance the state-of

Merging Land Use Change Trends and Insecticide Application to Understand Multiple Threats to Honey Bees in North Dakota

Science.gov (United States)

Dixon, D.; Zheng, H.; Otto, C.

2017-12-01

US beekeepers have historically relied on North Dakota for its rich floral grasslands and mild climate to harvest honey and maintain colony growth from May to September. Over 40% of registered apiaries used for crop pollination across the United States pass through the Northern Great Plains region for this reason. However, increased land use change from grassland to row crops has decreased available forage for honey bees and shrunken the already finite landscape suitable for apiary sites. Alongside the introduction of cropland followed the application of insecticides known to impact colony health. While landscape composition is one of the driving factors influencing honey bee productivity and overall health, the further application of insecticides adds an additional threat layer to the changing landscape. USGS E-pest estimates suggest an increasing application per cropland area over the past 10 years for harmful insecticidees including neonicotinoids, organophosphates and pyrethroids. This research aims to capture these trends by utilizing a spatially explicit habitat quality model from InVEST to integrate the following annual data in North Dakota from 2006-2014: (1) habitat suitability basemaps derived from the Cropland Data Layer (CDL); and (2) assign stacked layers of weighted values to those land covers based on estimated insecticide applications on individual crop types within each county year combination. We aim to utilize model outputs to learn where in time and space registered apiaries have experienced this double sided threat of decreased foraged and increased exposure to insecticides, but also ask further questions about how to improve the landscape with different scenarios.

The space between us: stereotype threat and distance in interracial contexts.

Science.gov (United States)

Goff, Phillip Atiba; Steele, Claude M; Davies, Paul G

2008-01-01

Four studies investigate the role that stereotype threat plays in producing racial distancing behavior in an anticipated conversation paradigm. It was hypothesized that the threat of appearing racist may have the ironic effect of causing Whites to distance themselves from Black conversation partners. In Study 1, participants distanced themselves more from Black partners under conditions of threat, and this distance correlated with the activation of a "White racist" stereotype. In Study 2, it was demonstrated that Whites' interracial distancing behavior was not predicted by explicit or implicit prejudice. Study 3 provides evidence that conceiving of interracial interactions as opportunities to learn may attenuate the negative consequences of threat for Whites. Study 4 found that Whites have conscious access to their experience of stereotype threat and that this awareness may mediate the relationship between threat and distance. These results are discussed within a broader discourse of racial distancing and the possibility that certain identity threats may be as important as prejudice in determining the outcomes of interracial interactions. Copyright 2008 APA, all rights reserved.

Improving Insider Threat Training Awareness and Mitigation Programs at Nuclear Facilities.

Energy Technology Data Exchange (ETDEWEB)

Abbott, Shannon [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2017-06-01

In recent years, insider threat programs have become an important aspect of nuclear security, and nuclear security training courses. However, many nuclear security insider threat programs fail to address the insider threat attack and monitoring potential that exists on information technology (IT) systems. This failure is critical because of the importance of information technology and networks in today’s world. IT systems offer an opportunity to perpetrate dangerous insider attacks, but they also present an opportunity to monitor for them and prevent them. This paper suggests a number of best practices for monitoring and preventing insider attacks on IT systems, and proposes the development of a new IT insider threat tabletop that can be used to help train nuclear security practitioners on how best to implement IT insider threat prevention best practices. The development of IT insider threat best practices and a practical tabletop exercise will allow nuclear security practitioners to improve nuclear security trainings as it integrates a critical part of insider threat prevention into the broader nuclear security system.

Introduction to Administrative Programs that Mitigate the Insider Threat

Energy Technology Data Exchange (ETDEWEB)

Gerke, Gretchen K.; Rogers, Erin; Landers, John; DeCastro, Kara

2012-09-01

This presentation begins with the reality of the insider threat, then elaborates on these tools to mitigate the insider threat: Human Reliability Program (HRP); Nuclear Security Culture (NSC) Program; Employee Assistance Program (EAP).

Interaction of threat and verbal working memory in adolescents.

Science.gov (United States)

Patel, Nilam; Vytal, Katherine; Pavletic, Nevia; Stoodley, Catherine; Pine, Daniel S; Grillon, Christian; Ernst, Monique

2016-04-01

Threat induces a state of sustained anxiety that can disrupt cognitive processing, and, reciprocally, cognitive processing can modulate an anxiety response to threat. These effects depend on the level of cognitive engagement, which itself varies as a function of task difficulty. In adults, we recently showed that induced anxiety impaired working memory accuracy at low and medium but not high load. Conversely, increasing the task load reduced the physiological correlates of anxiety (anxiety-potentiated startle). The present work examines such threat-cognition interactions as a function of age. We expected threat to more strongly impact working memory in younger individuals by virtue of putatively restricted cognitive resources and weaker emotion regulation. This was tested by examining the influence of age on the interaction of anxiety and working memory in 25 adolescents (10 to 17 years) and 25 adults (22 to 46 years). Working memory load was manipulated using a verbal n-back task. Anxiety was induced using the threat of an aversive loud scream and measured via eyeblink startle. Findings revealed that, in both age groups, accuracy was lower during threat than safe conditions at low and medium but not high load, and reaction times were faster during threat than safe conditions at high load but did not differ at other loads. Additionally, anxiety-potentiated startle was greater during low and medium than high load. Thus, the interactions of anxiety with working memory appear similar in adolescents and adults. Whether these similarities reflect common neural mechanisms would need to be assessed using functional neuroimaging. Published 2015. This article is a U.S. Government work and is in the public domain in the USA.

Age differences in the underlying mechanisms of stereotype threat effects.

Science.gov (United States)

Popham, Lauren E; Hess, Thomas M

2015-03-01

The goals of the present study were to (a) examine whether age differences exist in the mechanisms underlying stereotype threat effects on cognitive performance and (b) examine whether emotion regulation abilities may buffer against threat effects on performance. Older and younger adults were exposed to positive or negative age-relevant stereotypes, allowing us to examine the impact of threat on regulatory focus and working memory. Self-reported emotion regulation measures were completed prior to the session. Older adults' performance under threat suggested a prevention-focused approach to the task, indexed by increased accuracy and reduced speed. The same pattern was observed in younger adults, but the effects were not as strong. Age differences emerged when examining the availability of working memory resources under threat, with young adults showing decrements, whereas older adults did not. Emotion regulation abilities moderated threat effects in young adults but not in older adults. The results provide support for the notion that stereotype threat may lead to underperformance through somewhat different pathways in older and younger adults. Future research should further examine whether the underlying reason for this age difference is rooted in age-related improvements in emotion regulation. © The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

A Category Based Threat Evaluation Model Using Platform Kinematics Data

Directory of Open Access Journals (Sweden)

Mustafa Çöçelli

2017-08-01

Full Text Available Command and control (C2 systems direct operators to make accurate decisions in the stressful atmosphere of the battlefield at the earliest. There are powerful tools that fuse various instant piece of information and brings summary of those in front of operators. Threat evaluation is one of the important fusion method that provides these assistance to military people. However, C2 systems could be deprived of valuable data source due to the absence of capable equipment. This situation has a bad unfavorable influence on the quality of tactical picture in front of C2 operators. In this paper, we study on the threat evaluation model that take into account these deficiencies. Our method extracts threat level of various targets mostly from their kinematics in two dimensional space. In the meantime, classification of entities around battlefield is unavailable. Only, category of targets are determined as a result of sensors process, which is the information of whether entities belong to air or surface environment. Hereby, threat evaluation model is consist of three fundamental steps that runs on entities belongs to different environment separately: the extraction of threat assessment cues, threat selection based on Bayesian Inference and the calculation of threat assessment rating. We have evaluated performance of proposed model by simulating a set of synthetic scenarios.

Truck bomb and insider threats to nuclear facilities

International Nuclear Information System (INIS)

Hirsch, D.

1987-01-01

In the nuclear field, two the these weak links in the security chain are the truck bomb threat and the insider threat. The risks associated with terrorist use of vehicular bombs against nuclear targets surfaced (actually, resurfaced) followed the terrorist attacks on the US Embassy annex and the Marine compound in Leb Concern was expressed that similar attacks against nuclear facilities could result in substantial damage and release of radioactivity. Since the current regulations of the NRC require licensees to protect only against attacks on foot (and even then, only against very small attacking forces), shortly after the Lebanon bombings, that agency commenced an urgent rulemaking to require its licensees to protect against truck bombs. Inexplicably, that rulemaking was called off after research results indicated that the truck bomb threat to nuclear facilities was even more serious than previously thought. Even were nuclear facilities adequately protected against external attack, be the aim theft or sabotage, the greatest security risk to these sites - the threat of action by insiders - would remain. The traditional methods of protecting against the insider threat - such as the two-person rule, strict compartmentalization of vital areas, and design features that make damage to two or more redundant systems by one individual difficult - are generally expensive and have encountered substantial resistance from the nuclear industry, which has restrained the NRC from requiring them

NATIONAL SECURITY IMPLICATIONS OF CYBER THREATS

Directory of Open Access Journals (Sweden)

ALEJANDRO AMIGO TOSSI

2017-09-01

Full Text Available Cyber threat is one of the main risks for security in developing countries, as well in States on the development path, such as ours. This phenomena is a challenge to national security, that needs the adoption of a paramount approach in its analysis, that have to consider all the aspects that had transformed the actors and malevolent actions in this environment in one of the most important challenges to the security of governmental as well as private organizations all over the world. States, hackers, cyber activists, and cyber criminals have been main actors in several situations that had shaped a new dimension for international and national security. The purpose of this article is to propose topics that could be included in the national assessment of cyber threats to the Chilean national security, based upon several conceptual definitions, cyber attacks already executed to state and military organization’s in Chile, and lastly, considerations over cyber threats included in the National Security Strategies of some western powers.

Allostatic load and biological anthropology.

Science.gov (United States)

Edes, Ashley N; Crews, Douglas E

2017-01-01

Multiple stressors affect developing and adult organisms, thereby partly structuring their phenotypes. Determining how stressors influence health, well-being, and longevity in human and nonhuman primate populations are major foci within biological anthropology. Although much effort has been devoted to examining responses to multiple environmental and sociocultural stressors, no holistic metric to measure stress-related physiological dysfunction has been widely applied within biological anthropology. Researchers from disciplines outside anthropology are using allostatic load indices (ALIs) to estimate such dysregulation and examine life-long outcomes of stressor exposures, including morbidity and mortality. Following allostasis theory, allostatic load represents accumulated physiological and somatic damage secondary to stressors and senescent processes experienced over the lifespan. ALIs estimate this wear-and-tear using a composite of biomarkers representing neuroendocrine, cardiovascular, metabolic, and immune systems. Across samples, ALIs are associated significantly with multiple individual characteristics (e.g., age, sex, education, DNA variation) of interest within biological anthropology. They also predict future outcomes, including aspects of life history variation (e.g., survival, lifespan), mental and physical health, morbidity and mortality, and likely health disparities between groups, by stressor exposures, ethnicity, occupations, and degree of departure from local indigenous life ways and integration into external and commodified ones. ALIs also may be applied to similar stress-related research areas among nonhuman primates. Given the reports from multiple research endeavors, here we propose ALIs may be useful for assessing stressors, stress responses, and stress-related dysfunction, current and long-term cognitive function, health and well-being, and risk of early mortality across many research programs within biological anthropology. © 2017 American

Journal of Medical Chemical, Biological and Radiological Defense

International Nuclear Information System (INIS)

Price, B.

2007-01-01

The Journal of Medical Chemical, Biological, and Radiological Defense is a free, on-line journal dedicated to providing an international, peer-reviewed journal of original scientific research and clinical and doctrinal knowledge in the area of medical treatment and countermeasures for chemical, biological and radiological defense; and to developing and maintaining an archive of current research and development information on training, doctrine, and professional discussions of problems related to chemical, biological and radiological casualties. The Journal, www.JMedCBR.org, now in its fifth year, is sponsored by the US Defense Threat Reduction Agency. Areas of interest include, but are not limited to: Neuroprotectants; Bioscavengers for Nerve Agents; Medical Diagnostic Systems and Technologies; Medical Effects of Low Level Exposures; Toxicology and Biological Effects of TICs and TIMs; Broad Spectrum Medical Countermeasures; Treatments and Therapeutics for Bacterial, Viral and Toxin Agents; Radiological Medical Countermeasures; Clinical Treatment of Chemical, Biological or Radiological Casualties; Toxins Structures and Treatments. The Journal is supported by an editorial advisory board of distinguished scientists and researchers in the fields of CBR defense and medical treatment and countermeasures in eleven countries.(author)

The threat of proliferation

International Nuclear Information System (INIS)

Palme, Olof.

1986-01-01

The paper on the threat of proliferation, is a keynote speech delivered to the Colloquium on Nuclear War, Nuclear Proliferation and their Consequences, Geneva, 1985. Topics discussed in the address include: nuclear weapons, nuclear war, terrorists, Non-Proliferation Treaty, nuclear disarmament, and leadership in world affairs. (UK)

Defense against Insider Threat: a Framework for Gathering Goal-based Requirements

NARCIS (Netherlands)

Nunes Leal Franqueira, V.; van Eck, Pascal; Pernici, B; Gulla, J.A.

2007-01-01

Insider threat is becoming comparable to outsider threat in frequency of security events. This is a worrying situation, since insider attacks have a high probability of success because insiders have authorized access and legitimate privileges. Despite their importance, insider threats are still not

Increasing Awareness of Insider Information Security Threats in Human Resource Department

OpenAIRE

Burcin Cetin Karabat; Cagatay Karabat

2012-01-01

An insider threat for companies is defined as a threat caused by malicious user who is an employee company. In recent years, there are number of work on insider threats in information security technologies. These works shows that companies should increasingly and seriously should take into account these threats. Human factors in companies constitute one of the weakest links in information security technology and its products used in human resource (HR) management departments. In the literatur...

Biological Select Agents and Toxins: Risk-Based Assessment Management and Oversight.

Energy Technology Data Exchange (ETDEWEB)

Burnett, LouAnn Crawford; Brodsky, Benjamin H.

2016-12-01

Sandia National Laboratories' International Biological and Chemical Threat Reduction (SNL/IBCTR) conducted, on behalf of the Federal Select Agent Program (FSAP), a review of risk assessment in modern select agent laboratories. This review and analysis consisted of literature review, interviews of FSAP staff, entities regulated by FSAP, and deliberations of an expert panel. Additionally, SNL/IBCTR reviewed oversight mechanisms used by industries, US agencies, and other countries for high-consequence risks (e.g, nuclear, chemical, or biological materials, aviation, off-shore drilling, etc.) to determine if alternate oversight mechanisms existed that might be applicable to FSAP oversight of biological select agents and toxins. This report contains five findings, based on these reviews and analyses, with recommendations and suggested actions for FSAP to consider.

Iraqi adolescents: self-regard, self-derogation, and perceived threat in war.

Science.gov (United States)

Carlton-Ford, Steve; Ender, Morten G; Tabatabai, Ahoo

2008-02-01

A year into the 2003 US-Iraq war, how were adolescents in Baghdad faring? Conflict-related events typically lower psychological well-being; in contrast, investment in and protection of threatened identities should lead to self-esteem striving and, presumably, better well-being. How threatened do Iraqi adolescents feel? Is their self-esteem related to their sense of threat? Do age, religion, ethnicity, and gender alter the link between perceived threat and self-esteem? We use data from 1000 randomly selected adolescents living in Baghdad during July 2004. Iraqi adolescents reported high levels of threat; those feeling more threatened reported higher levels of self-esteem. Social background correlates with both self-esteem and perceived threat, but controlling for social background does not eliminate the relationship between self-esteem and perceived threat. We interpret our results in light of theory and research concerning social identity, mortality threats, and war trauma.

"Exclusive Dealing Contract and Inefficient Entry Threat"

OpenAIRE

Noriyuki Yanagawa; Ryoko Oki

2008-01-01

This paper examines the effects of exclusive dealing contracts in a simple model with manufacturers-distributors relations. We consider entrants in both manufacturing and distribution sectors. It is well-known that a potential entry threat is welfare increasing under homogenous price competition, even though the potential entrant is less productive. This paper reexamines this intuition by employing the above model. We show that the entry threat of a less-productive manufacturer is welfare dec...

Phishing - A Growing Threat to E-Commerce

OpenAIRE

Banday, M. Tariq; Qadri, Jameel A.

2011-01-01

In today's business environment, it is difficult to imagine a workplace without access to the web, yet a variety of email born viruses, spyware, adware, Trojan horses, phishing attacks, directory harvest attacks, DoS attacks, and other threats combine to attack businesses and customers. This paper is an attempt to review phishing - a constantly growing and evolving threat to Internet based commercial transactions. Various phishing approaches that include vishing, spear phishng, pharming, keyl...

Exciting fear in adolescence: Does pubertal development alter threat processing?

Directory of Open Access Journals (Sweden)

Jeffrey M. Spielberg

2014-04-01

Full Text Available Adolescent development encompasses an ostensible paradox in threat processing. Risk taking increases dramatically after the onset of puberty, contributing to a 200% increase in mortality. Yet, pubertal maturation is associated with increased reactivity in threat-avoidance systems. In the first part of this paper we propose a heuristic model of adolescent affective development that may help to reconcile aspects of this paradox, which focuses on hypothesized pubertal increases in the capacity to experience (some fear-evoking experiences as an exciting thrill. In the second part of this paper, we test key features of this model by examining brain activation to threat cues in a longitudinal study that disentangled pubertal and age effects. Pubertal increases in testosterone predicted increased activation to threat cues, not only in regions associated with threat avoidance (i.e., amygdala, but also regions associated with reward pursuit (i.e., nucleus accumbens. These findings are consistent with our hypothesis that puberty is associated with a maturational shift toward more complex processing of threat cues—which may contribute to adolescent tendencies to explore and enjoy some types of risky experiences.

Exciting fear in adolescence: does pubertal development alter threat processing?

Science.gov (United States)

Spielberg, Jeffrey M; Olino, Thomas M; Forbes, Erika E; Dahl, Ronald E

2014-04-01

Adolescent development encompasses an ostensible paradox in threat processing. Risk taking increases dramatically after the onset of puberty, contributing to a 200% increase in mortality. Yet, pubertal maturation is associated with increased reactivity in threat-avoidance systems. In the first part of this paper we propose a heuristic model of adolescent affective development that may help to reconcile aspects of this paradox, which focuses on hypothesized pubertal increases in the capacity to experience (some) fear-evoking experiences as an exciting thrill. In the second part of this paper, we test key features of this model by examining brain activation to threat cues in a longitudinal study that disentangled pubertal and age effects. Pubertal increases in testosterone predicted increased activation to threat cues, not only in regions associated with threat avoidance (i.e., amygdala), but also regions associated with reward pursuit (i.e., nucleus accumbens). These findings are consistent with our hypothesis that puberty is associated with a maturational shift toward more complex processing of threat cues--which may contribute to adolescent tendencies to explore and enjoy some types of risky experiences. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

Use of media and public-domain Internet sources for detection and assessment of plant health threats.

Science.gov (United States)

Thomas, Carla S; Nelson, Noele P; Jahn, Gary C; Niu, Tianchan; Hartley, David M

2011-09-05

Event-based biosurveillance is a recognized approach to early warning and situational awareness of emerging health threats. In this study, we build upon previous human and animal health work to develop a new approach to plant pest and pathogen surveillance. We show that monitoring public domain electronic media for indications and warning of epidemics and associated social disruption can provide information about the emergence and progression of plant pest infestation or disease outbreak. The approach is illustrated using a case study, which describes a plant pest and pathogen epidemic in China and Vietnam from February 2006 to December 2007, and the role of ducks in contributing to zoonotic virus spread in birds and humans. This approach could be used as a complementary method to traditional plant pest and pathogen surveillance to aid global and national plant protection officials and political leaders in early detection and timely response to significant biological threats to plant health, economic vitality, and social stability. This study documents the inter-relatedness of health in human, animal, and plant populations and emphasizes the importance of plant health surveillance.

Potential Threats of Information Disclosure in Social Media: a Systematic Literature Review

Directory of Open Access Journals (Sweden)

Budi Yulianto

2016-09-01

Full Text Available Along with the growth of social media, a variety of potential threats to users is also increasing. These kinds of threats often occur because the users accidentally or unknowingly disclose their information or identity on social media. Threats resulted from the disclosure of information are needed to be known so that the users can understand the risks that arise and take precautions. This research was aimed to summarize the potential threats arising from the information disclosure in social media. The research method used was a systematic literature review to explore and summarize the literatures that discuss the specific topic. The research results show that the potential threats are mostly social threats and identity theft. 

Performance Assessment of Communication Enhancement Devices TEA HI Threat Headset

Science.gov (United States)

2015-08-01

AFRL-RH-WP-TR-2015-0076 Performance Assessment of Communication Enhancement Devices: TEA HI Threat Headset Hilary L. Gallagher...of Communication Enhancement Devices: TEA HI Threat Headset 5a. CONTRACT NUMBER FA8650-14-D-6501 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER...technology in military applications. Objective performance data provided an assessment of the performance of these devices. The TEA HI Threat headset

The Threat Among Us: Insiders Intensify Aviation Terrorism

Energy Technology Data Exchange (ETDEWEB)

Krull, Katie E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

2016-08-19

Aviation terrorism is powerful and symbolic, and will likely remain a staple target for terrorists aiming to inflict chaos and cause mass casualties similar to the 9/11 attacks on the U.S. The majority of international and domestic aviation terrorist attacks involves outsiders, or people who do not have direct access to or affiliation with a target through employment. However, several significant attacks and plots against the industry involved malicious employees motivated by suicide or devotion to a terrorist organization. Malicious insiders’ access and knowledge of aviation security, systems, networks, and infrastructure is valuable to terrorists, providing a different pathway for attacking the industry through the insider threat. Indicators and warnings of insider threats in these cases exist, providing insight into how security agencies, such as the Transportation Security Administration, can better predict and identify insider involvement. Understanding previous aviation insider threat events will likely aid in stimulating proactive security measures, rather than reactive responses. However, similar to traditional airport security measures, there are social, political, and economic challenges in protecting against the insider threat, including privacy concerns and cost-benefit analysis.

Exploring the function of selective attention and hypervigilance for threat in anxiety.

Science.gov (United States)

Richards, Helen J; Benson, Valerie; Donnelly, Nick; Hadwin, Julie A

2014-02-01

Theoretical frameworks of anxiety propose that attentional biases to threat-related stimuli cause or maintain anxious states. The current paper draws on theoretical frameworks and key empirical studies to outline the distinctive attentional processes highlighted as being important in understanding anxiety. We develop a conceptual framework to make a distinction between two attentional biases: selective attention to threat and hypervigilance for threat. We suggest that these biases each have a different purpose and can account for the typical patterns of facilitated and impaired attention evident in anxious individuals. The framework is novel in its specification of the eye movement behavior associated with these attentional biases. We highlight that selective attention involves narrowing overt attention onto threat to ensure that these stimuli receive processing priority, leading to rapid engagement with task-relevant threat and delayed disengagement from task-irrelevant threat. We show that hypervigilance operates in the presence and absence of threat and involves monitoring for potential dangers via attentional broadening or excessive scanning of the environment with numerous eye movements, leading to improved threat detection and increased distraction from task-irrelevant threat. We conclude that future research could usefully employ eye movement measures to more clearly understand the diverse roles of attention in anxiety. Copyright © 2013 Elsevier Ltd. All rights reserved.

Systems Biology-Based Platforms to Accelerate Research of Emerging Infectious Diseases.

Science.gov (United States)

Oh, Soo Jin; Choi, Young Ki; Shin, Ok Sarah

2018-03-01

Emerging infectious diseases (EIDs) pose a major threat to public health and security. Given the dynamic nature and significant impact of EIDs, the most effective way to prevent and protect against them is to develop vaccines in advance. Systems biology approaches provide an integrative way to understand the complex immune response to pathogens. They can lead to a greater understanding of EID pathogenesis and facilitate the evaluation of newly developed vaccine-induced immunity in a timely manner. In recent years, advances in high throughput technologies have enabled researchers to successfully apply systems biology methods to analyze immune responses to a variety of pathogens and vaccines. Despite recent advances, computational and biological challenges impede wider application of systems biology approaches. This review highlights recent advances in the fields of systems immunology and vaccinology, and presents ways that systems biology-based platforms can be applied to accelerate a deeper understanding of the molecular mechanisms of immunity against EIDs. © Copyright: Yonsei University College of Medicine 2018.

Assessment of terrorist threats to the Canadian energy sector

Energy Technology Data Exchange (ETDEWEB)

Shull, A. [Carleton Univ., Ottawa, ON (Canada). Norman Paterson School of International Affairs]|[Ottawa Univ., ON (Canada). Faculty of Law

2006-03-15

A critical terrorist threat assessment of Canadian energy systems was presented, as well as an analysis of integrated continental systems. Recent responses to heightened threat levels on the part of the Canadian government have ranged from information sharing to emergency preparedness and disaster mitigation strategies. This paper examined threats that the energy sector has traditionally encountered and argued that response capabilities do not match current threats posed by terrorism. The potential of a terrorist attack on the Canadian energy infrastructure is significant and has been referred to as a possible target by terrorist organizations. Actions taken by the Canadian government in response to heightened threat levels were examined. A review of energy industry security measures included outlines of: the natural gas industry, the electric sector, and nuclear reactors and waste. It was noted that not all elements of the critical energy infrastructure share the same level of risk. Recommendations included increased information sharing between government agencies and the private sector; resiliency standards in densely populated areas; and insulating the energy grid against a cascading blackout through the use of DC rather than AC lines. 59 refs.

Assessment of terrorist threats to the Canadian energy sector

International Nuclear Information System (INIS)

Shull, A.

2006-01-01

A critical terrorist threat assessment of Canadian energy systems was presented, as well as an analysis of integrated continental systems. Recent responses to heightened threat levels on the part of the Canadian government have ranged from information sharing to emergency preparedness and disaster mitigation strategies. This paper examined threats that the energy sector has traditionally encountered and argued that response capabilities do not match current threats posed by terrorism. The potential of a terrorist attack on the Canadian energy infrastructure is significant and has been referred to as a possible target by terrorist organizations. Actions taken by the Canadian government in response to heightened threat levels were examined. A review of energy industry security measures included outlines of: the natural gas industry, the electric sector, and nuclear reactors and waste. It was noted that not all elements of the critical energy infrastructure share the same level of risk. Recommendations included increased information sharing between government agencies and the private sector; resiliency standards in densely populated areas; and insulating the energy grid against a cascading blackout through the use of DC rather than AC lines. 59 refs

The cyber threat landscape: Challenges and future research directions

Science.gov (United States)

Gil, Santiago; Kott, Alexander; Barabási, Albert-László

2014-07-01

While much attention has been paid to the vulnerability of computer networks to node and link failure, there is limited systematic understanding of the factors that determine the likelihood that a node (computer) is compromised. We therefore collect threat log data in a university network to study the patterns of threat activity for individual hosts. We relate this information to the properties of each host as observed through network-wide scans, establishing associations between the network services a host is running and the kinds of threats to which it is susceptible. We propose a methodology to associate services to threats inspired by the tools used in genetics to identify statistical associations between mutations and diseases. The proposed approach allows us to determine probabilities of infection directly from observation, offering an automated high-throughput strategy to develop comprehensive metrics for cyber-security.

Nuclear power threats, public opposition and green electricity adoption: Effects of threat belief appraisal and fear arousal

International Nuclear Information System (INIS)

Hartmann, Patrick; Apaolaza, Vanessa; D'Souza, Clare; Echebarria, Carmen; Barrutia, Jose M.

2013-01-01

This study analyses the extent to which willingness to oppose nuclear power and intention to adopt green electricity are related to the cognitive and emotional appraisal of threats deriving from nuclear power. The analysis draws on a theoretical framework which introduces emotional fear arousal as a direct behavioural antecedent of coping behaviour into a model based on cognitive centred Protection Motivation Theory (PMT, Maddux and Rogers, 1983; Rogers, 1983) and the Extended Parallel Processing Model (EPPM, Witte, 1992, 1998). Hypothesized relations are tested in a nationally representative online study conducted in April and May 2012, one year after the Fukushima accident. Results support the hypothesized influences of perceived threat, fear arousal and perceived coping efficacy. Support for the proposed effects of fear control is rather limited. Findings contribute to extending previous knowledge on the role of cognitive and emotional appraisal processes induced by awareness of threats from nuclear power as behavioural antecedents of both opposing nuclear power and adopting green electricity. Findings of the study have implications for nuclear power policy and activism, as well as for institutional and commercial promoters of voluntary residential green electricity adoption. - Highlights: • Nationally representative online survey on nuclear power conducted in Spain in April and May 2012. • Opposition to nuclear power and green electricity adoption are related to threat beliefs. • Emotional fear arousal motivates nuclear opposition and green electricity uptake. • Significant behavioural effects of coping efficacy are confirmed. • Influences of fear control on behaviour intentions are rather weak

The Convergence of Virtual Reality and Social Networks: Threats to Privacy and Autonomy.

Science.gov (United States)

O'Brolcháin, Fiachra; Jacquemard, Tim; Monaghan, David; O'Connor, Noel; Novitzky, Peter; Gordijn, Bert

2016-02-01

The rapid evolution of information, communication and entertainment technologies will transform the lives of citizens and ultimately transform society. This paper focuses on ethical issues associated with the likely convergence of virtual realities (VR) and social networks (SNs), hereafter VRSNs. We examine a scenario in which a significant segment of the world's population has a presence in a VRSN. Given the pace of technological development and the popularity of these new forms of social interaction, this scenario is plausible. However, it brings with it ethical problems. Two central ethical issues are addressed: those of privacy and those of autonomy. VRSNs pose threats to both privacy and autonomy. The threats to privacy can be broadly categorized as threats to informational privacy, threats to physical privacy, and threats to associational privacy. Each of these threats is further subdivided. The threats to autonomy can be broadly categorized as threats to freedom, to knowledge and to authenticity. Again, these three threats are divided into subcategories. Having categorized the main threats posed by VRSNs, a number of recommendations are provided so that policy-makers, developers, and users can make the best possible use of VRSNs.

Application of heterogeneous multiple camera system with panoramic capabilities in a harbor environment

NARCIS (Netherlands)

Schwering, P.B.W.; Lensen, H.A.; Broek, S.P. van den; Hollander, R.J.M. den; Mark, W. van der; Bouma, H.; Kemp, R.A.W.

2009-01-01

In a harbor environment threats like explosives-packed rubber boats, mine-carrying swimmers and divers must be detected in an early stage. This paper describes the integration and use of a heterogeneous multiple camera system with panoramic observation capabilities for detecting these small vessels

Space Station Program threat and vulnerability analysis

Science.gov (United States)

Van Meter, Steven D.; Veatch, John D.

1987-01-01

An examination has been made of the physical security of the Space Station Program at the Kennedy Space Center in a peacetime environment, in order to furnish facility personnel with threat/vulnerability information. A risk-management approach is used to prioritize threat-target combinations that are characterized in terms of 'insiders' and 'outsiders'. Potential targets were identified and analyzed with a view to their attractiveness to an adversary, as well as to the consequentiality of the resulting damage.

Cultural adaptations to the differential threats posed by hot versus cold climates.

Science.gov (United States)

Murray, Damian R

2013-10-01

Hot and cold climates have posed differential threats to human survival throughout history. Cold temperatures can pose direct threats to survival in themselves, whereas hot temperatures may pose threats indirectly through higher prevalence of infectious disease. These differential threats yield convergent predictions for the relationship between more demanding climates and freedom of expression, but divergent predictions for freedom from discrimination.

Analyzing Cyber-Physical Threats on Robotic Platforms.

Science.gov (United States)

Ahmad Yousef, Khalil M; AlMajali, Anas; Ghalyon, Salah Abu; Dweik, Waleed; Mohd, Bassam J

2018-05-21

Robots are increasingly involved in our daily lives. Fundamental to robots are the communication link (or stream) and the applications that connect the robots to their clients or users. Such communication link and applications are usually supported through client/server network connection. This networking system is amenable of being attacked and vulnerable to the security threats. Ensuring security and privacy for robotic platforms is thus critical, as failures and attacks could have devastating consequences. In this paper, we examine several cyber-physical security threats that are unique to the robotic platforms; specifically the communication link and the applications. Threats target integrity, availability and confidential security requirements of the robotic platforms, which use MobileEyes/arnlServer client/server applications. A robot attack tool (RAT) was developed to perform specific security attacks. An impact-oriented approach was adopted to analyze the assessment results of the attacks. Tests and experiments of attacks were conducted in simulation environment and physically on the robot. The simulation environment was based on MobileSim; a software tool for simulating, debugging and experimenting on MobileRobots/ActivMedia platforms and their environments. The robot platform PeopleBot TM was used for physical experiments. The analysis and testing results show that certain attacks were successful at breaching the robot security. Integrity attacks modified commands and manipulated the robot behavior. Availability attacks were able to cause Denial-of-Service (DoS) and the robot was not responsive to MobileEyes commands. Integrity and availability attacks caused sensitive information on the robot to be hijacked. To mitigate security threats, we provide possible mitigation techniques and suggestions to raise awareness of threats on the robotic platforms, especially when the robots are involved in critical missions or applications.

Analyzing Cyber-Physical Threats on Robotic Platforms

Directory of Open Access Journals (Sweden)

Khalil M. Ahmad Yousef

2018-05-01

Full Text Available Robots are increasingly involved in our daily lives. Fundamental to robots are the communication link (or stream and the applications that connect the robots to their clients or users. Such communication link and applications are usually supported through client/server network connection. This networking system is amenable of being attacked and vulnerable to the security threats. Ensuring security and privacy for robotic platforms is thus critical, as failures and attacks could have devastating consequences. In this paper, we examine several cyber-physical security threats that are unique to the robotic platforms; specifically the communication link and the applications. Threats target integrity, availability and confidential security requirements of the robotic platforms, which use MobileEyes/arnlServer client/server applications. A robot attack tool (RAT was developed to perform specific security attacks. An impact-oriented approach was adopted to analyze the assessment results of the attacks. Tests and experiments of attacks were conducted in simulation environment and physically on the robot. The simulation environment was based on MobileSim; a software tool for simulating, debugging and experimenting on MobileRobots/ActivMedia platforms and their environments. The robot platform PeopleBotTM was used for physical experiments. The analysis and testing results show that certain attacks were successful at breaching the robot security. Integrity attacks modified commands and manipulated the robot behavior. Availability attacks were able to cause Denial-of-Service (DoS and the robot was not responsive to MobileEyes commands. Integrity and availability attacks caused sensitive information on the robot to be hijacked. To mitigate security threats, we provide possible mitigation techniques and suggestions to raise awareness of threats on the robotic platforms, especially when the robots are involved in critical missions or applications.

Stereotype threat reduces false recognition when older adults are forewarned.

Science.gov (United States)

Wong, Jessica T; Gallo, David A

2016-01-01

Exposing older adults to ageing stereotypes can reduce their memory for studied information--a phenomenon attributed to stereotype threat--but little is known about stereotype effects on false memory. Here, we assessed ageing stereotype effects on the Deese-Roediger-McDermott false memory illusion. Older adults studied lists of semantically associated words, and then read a passage about age-related memory decline (threat condition) or an age-neutral passage (control condition). They then took a surprise memory test with a warning to avoid false recognition of non-studied associates. Relative to the control condition, activating stereotype threat reduced the recognition of both studied and non-studied words, implicating a conservative criterion shift for associated test words. These results indicate that stereotype threat can reduce false memory, and they help to clarify mixed results from prior ageing research. Consistent with the regulatory focus hypothesis, threat motivates older adults to respond more conservatively when error-prevention is emphasised at retrieval.

The threat from without

Directory of Open Access Journals (Sweden)

Lassi Saressalo

1987-01-01

Full Text Available Of greatest importance in ethnic folklore are the recognised and unrecognised elements that are used when founding identity on tradition. For the aim of ethnic identification is to note and know the cultural features that connect me with people like me and separate me from people who are not like me. Every group and each of its members thus needs an opponent, a contact partner in order to identify itself. What about the Lapps? The ethnocentric values of ethnic folklore provide a model for this generalising comparison. 'They' are a potential danger, are unknown, strange, a threat from beyond the fells. They are sufficiently common for the group's ethnic feeling. It is here that we find tradition, folk tales, describing the community's traditional enemies, describing the threat from without, engendering preconceived ideas, conflicts and even war. The Lapps have never had an empire, they have never conquered others' territory, they have never engaged in systematic warfare against other peoples. For this reason Lapp tradition lacks an offensive ethnic folklore proper with emphasis on aggression, power, violence, heroism and an acceptance of the ideology of subordinating others. On the contrary,Lapp folklore is familiar with a tradition in which strangers are always threatening the Lapps' existence, plundering their territories, burning and destroying. The Lapp has always had to fight against alien powers, to give in or to outwit the great and powerful enemy. In the Lapp tradition the staalo represents an outside threat that cannot be directly concretised. If foes are regarded as concrete enemies that may be defeated in physical combat or that can be made to look ridiculous, a staalo is more mythical, more supranormal, more vague. One basic feature of the staalo tradition is that it only appears as one party to a conflict. The stories about the Lapp who succeeds in driving away a staalo threatening the community, to outwit the stupid giant or to kill

Threat driven modeling framework using petri nets for e-learning system.

Science.gov (United States)

Khamparia, Aditya; Pandey, Babita

2016-01-01

Vulnerabilities at various levels are main cause of security risks in e-learning system. This paper presents a modified threat driven modeling framework, to identify the threats after risk assessment which requires mitigation and how to mitigate those threats. To model those threat mitigations aspects oriented stochastic petri nets are used. This paper included security metrics based on vulnerabilities present in e-learning system. The Common Vulnerability Scoring System designed to provide a normalized method for rating vulnerabilities which will be used as basis in metric definitions and calculations. A case study has been also proposed which shows the need and feasibility of using aspect oriented stochastic petri net models for threat modeling which improves reliability, consistency and robustness of the e-learning system.

Age Differences in Selective Memory of Goal-Relevant Stimuli Under Threat.

Science.gov (United States)

Durbin, Kelly A; Clewett, David; Huang, Ringo; Mather, Mara

2018-02-01

When faced with threat, people often selectively focus on and remember the most pertinent information while simultaneously ignoring any irrelevant information. Filtering distractors under arousal requires inhibitory mechanisms, which take time to recruit and often decline in older age. Despite the adaptive nature of this ability, relatively little research has examined how both threat and time spent preparing these inhibitory mechanisms affect selective memory for goal-relevant information across the life span. In this study, 32 younger and 31 older adults were asked to encode task-relevant scenes, while ignoring transparent task-irrelevant objects superimposed onto them. Threat levels were increased on some trials by threatening participants with monetary deductions if they later forgot scenes that followed threat cues. We also varied the time between threat induction and a to-be-encoded scene (i.e., 2 s, 4 s, 6 s) to determine whether both threat and timing effects on memory selectivity differ by age. We found that age differences in memory selectivity only emerged after participants spent a long time (i.e., 6 s) preparing for selective encoding. Critically, this time-dependent age difference occurred under threatening, but not neutral, conditions. Under threat, longer preparation time led to enhanced memory for task-relevant scenes and greater memory suppression of task-irrelevant objects in younger adults. In contrast, increased preparation time after threat induction had no effect on older adults' scene memory and actually worsened memory suppression of task-irrelevant objects. These findings suggest that increased time to prepare top-down encoding processes benefits younger, but not older, adults' selective memory for goal-relevant information under threat. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Using Motivational Interviewing to reduce threats in conversations about environmental behavior

Directory of Open Access Journals (Sweden)

Florian Erik Klonek

2015-07-01

Full Text Available Human behavior contributes to a waste of environmental resources and our society is looking for ways to reduce this problem. However, humans may perceive feedback about their environmental behavior as threatening. According to self-determination theory (SDT, threats decrease intrinsic motivation for behavior change. According to self-affirmation theory (SAT, threats can harm individuals’ self-integrity. Therefore, individuals should show self-defensive biases, e.g., in terms of presenting counter-arguments when presented with environmental behavior change. The current study examines how change recipients respond to threats from change agents in interactions about environmental behavior change. Moreover, we investigate how Motivational Interviewing (MI—an intervention aimed at increasing intrinsic motivation—can reduce threats at both the social and cognitive level. We videotaped 68 dyadic interactions with change agents who either did or did not use MI (control group. We coded agents verbal threats and recipients’ verbal expressions of motivation. Recipients also rated agents’ level of confrontation and empathy (i.e., cognitive reactions. As hypothesized, threats were significantly lower when change agents used MI. Perceived confrontations converged with observable social behavior of change agents in both groups. Moreover, behavioral threats showed a negative association with change recipients’ expressed motivation (i.e., reasons to change. Contrary to our expectations, we found no relation between change agents’ verbal threats and change recipients’ verbally expressed self-defenses (i.e., sustain talk. Our results imply that MI reduces the adverse impact of threats in conversations about environmental behavior change on both the social and cognitive level. We discuss theoretical implications of our study in the context of SAT and SDT and suggest practical implications for environmental change agents in organizations.

Using Motivational Interviewing to reduce threats in conversations about environmental behavior.

Science.gov (United States)

Klonek, Florian E; Güntner, Amelie V; Lehmann-Willenbrock, Nale; Kauffeld, Simone

2015-01-01

Human behavior contributes to a waste of environmental resources and our society is looking for ways to reduce this problem. However, humans may perceive feedback about their environmental behavior as threatening. According to self-determination theory (SDT), threats decrease intrinsic motivation for behavior change. According to self-affirmation theory (SAT), threats can harm individuals' self-integrity. Therefore, individuals should show self-defensive biases, e.g., in terms of presenting counter-arguments when presented with environmental behavior change. The current study examines how change recipients respond to threats from change agents in interactions about environmental behavior change. Moreover, we investigate how Motivational Interviewing (MI) - an intervention aimed at increasing intrinsic motivation - can reduce threats at both the social and cognitive level. We videotaped 68 dyadic interactions with change agents who either did or did not use MI (control group). We coded agents verbal threats and recipients' verbal expressions of motivation. Recipients also rated agents' level of confrontation and empathy (i.e., cognitive reactions). As hypothesized, threats were significantly lower when change agents used MI. Perceived confrontations converged with observable social behavior of change agents in both groups. Moreover, behavioral threats showed a negative association with change recipients' expressed motivation (i.e., reasons to change). Contrary to our expectations, we found no relation between change agents' verbal threats and change recipients' verbally expressed self-defenses (i.e., sustain talk). Our results imply that MI reduces the adverse impact of threats in conversations about environmental behavior change on both the social and cognitive level. We discuss theoretical implications of our study in the context of SAT and SDT and suggest practical implications for environmental change agents in organizations.

Strategic threat management: an exploration of nursing strategies in the pediatric intensive care unit.

Science.gov (United States)

Durso, Francis T; Ferguson, Ashley N; Kazi, Sadaf; Cunningham, Charlene; Ryan, Christina

2015-03-01

Part of the work of a critical care nurse is to manage the threats that arise that could impede efficient and effective job performance. Nurses manage threats by employing various strategies to keep performance high and workload manageable. We investigated strategic threat management by using the Threat-Strategy Interview. Threats frequently involved technology, staff, or organizational components. The threats were managed by a toolbox of multifaceted strategies, the most frequent of which involved staff-, treatment- (patient + technology), examination- (patient + clinician), and patient-oriented strategies. The profile of strategies for a particular threat often leveraged work facets similar to the work facet that characterized the threat. In such cases, the nurse's strategy was directed at eliminating the threat (not working around it). A description at both a domain invariant level - useful for understanding strategic threat management generally - and a description at an operational, specific level - useful for guiding interventions-- are presented. A structural description of the relationship among threats, strategies, and the cues that trigger them is presented in the form of an evidence accumulation framework of strategic threat management. Copyright © 2014 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Attentional bias towards health-threat information in chronic fatigue syndrome.

Science.gov (United States)

Hou, Ruihua; Moss-Morris, Rona; Bradley, Brendan P; Peveler, Robert; Mogg, Karin

2008-07-01

To investigate whether individuals with chronic fatigue syndrome (CFS) show an attentional bias towards health-threat information. Attentional bias (AB) was assessed in individuals with CFS and healthy controls using a visual probe task which presented health-threat and neutral words and pictures for 500 ms. Self-report questionnaires were used to assess CFS symptoms, depression, anxiety, and social desirability. Compared to a healthy control group, the CFS group showed an enhanced AB towards heath-threat stimuli relative to neutral stimuli. The AB was not influenced by the type of stimulus (pictures vs. words). The finding of an AB towards health-threat information in individuals with CFS is supportive of models of CFS which underlie cognitive behavior therapy.

Ex-ante analysis of economic returns from biological control of coconut mite in Tanzania

NARCIS (Netherlands)

Oleke, J.M.; Manyong, V.; Mignouna, D.; Isinika, A.; Mutabazi, K.; Hanna, R.; Sabelis, M.

2013-01-01

The coconut mite, Aceria guerreronis Keifer, has been identified as one of the pests that pose a threat to the coconut industry in Benin. The study presents the simulation results of the economic benefits of the biological control of coconut mites in Benin using a standard economic surplus model. In

Solanaceae plant malformation in Chongqing City, China, reveals a pollution threat to the Yangtze River.

Science.gov (United States)

Zhang, Hongbo; Liu, Guanshan; Timko, Michael P; Li, Jiana; Wang, Wenjing; Ma, Haoran

2014-10-21

Water quality is under increasing threat from industrial and natural sources of pollutants. Here, we present our findings about a pollution incident involving the tap water of Chongqing City in China. In recent years, Solanaceae plants grown in greenhouses in this city have displayed symptoms of cupped, strappy leaves. These symptoms resembled those caused by chlorinated auxinic herbicides. We have determined that these symptoms were caused by the tap water used for irrigation. Using a bioactivity-guided fractionation method, we isolated a substance with corresponding auxinic activity from the tap water. The substance was named "solanicide" because of its strong bioactivity against Solanaceae plants. Further investigation revealed that the solanicide in the water system of Chongqing City is derived from the Jialing River, a major tributary of the Yangtze River. Therefore, it is also present in the Yangtze River downstream of Chongqing after the inflow of the Jialing River. Biological analyses indicated that solanicide is functionally similar to, but distinct from, other known chlorinated auxinic herbicides. Chemical assays further showed that solanicide structurally differs from those compounds. This study has highlighted a water pollution threat to the Yangtze River and its floodplain ecosystem.

A threat analysis framework as applied to critical infrastructures in the Energy Sector.

Energy Technology Data Exchange (ETDEWEB)

Michalski, John T.; Duggan, David Patrick

2007-09-01

The need to protect national critical infrastructure has led to the development of a threat analysis framework. The threat analysis framework can be used to identify the elements required to quantify threats against critical infrastructure assets and provide a means of distributing actionable threat information to critical infrastructure entities for the protection of infrastructure assets. This document identifies and describes five key elements needed to perform a comprehensive analysis of threat: the identification of an adversary, the development of generic threat profiles, the identification of generic attack paths, the discovery of adversary intent, and the identification of mitigation strategies.

A simple strategy to reduce stereotype threat for orthopedic residents.

Science.gov (United States)

Gomez, Everlyne; Wright, James G

2014-04-01

Stereotype threat, defined as the predicament felt by people in either positive or negative learning experiences where they could conform to negative stereotypes associated with their own group membership, can interfere with learning. The purpose of this study was to determine if a simple orientation session could reduce stereotype threat for orthopedic residents. The intervention group received an orientation on 2 occasions focusing on their possible responses to perceived poor performance in teaching rounds and the operating room (OR). Participants completed a survey with 7 questions typical for stereotype threat evaluating responses to their experiences. The questions had 7 response options with a maximum total score of 49, where higher scores indicated greater degree of experiences typical of stereotype threat. Of the 84 eligible residents, 49 participated: 22 in the nonintervention and 27 in the intervention group. The overall scores were 29 and 29.4, and 26.2 and 25.8 in the nonintervention and intervention groups for their survey responses to perceived poor performance in teaching rounds (p = 0.85) and the OR (p = 0.84), respectively. Overall, responses typical of stereotype threat were greater for perceived poor performance at teaching rounds than in the OR (p = 0.001). Residents experience low self-esteem following perceived poor performance, particularly at rounds. A simple orientation designed to reduce stereotype threat was unsuccessful in reducing this threat overall. Future research will need to consider longer-term intervention as possible strategies to reduce perceived poor performance at teaching rounds and in the OR.

Investigation of a Markov Model for Computer System Security Threats

Directory of Open Access Journals (Sweden)

Alexey A. A. Magazev

2017-01-01

Full Text Available In this work, a model for computer system security threats formulated in terms of Markov processes is investigated. In the framework of this model the functioning of the computer system is considered as a sequence of failures and recovery actions which appear as results of information security threats acting on the system. We provide a detailed description of the model: the explicit analytical formulas for the probabilities of computer system states at any arbitrary moment of time are derived, some limiting cases are discussed, and the long-run dynamics of the system is analysed. The dependence of the security state probability (i.e. the state for which threats are absent on the probabilities of threats is separately investigated. In particular, it is shown that this dependence is qualitatively different for odd and even moments of time. For instance, in the case of one threat the security state probability demonstrates non-monotonic dependence on the probability of threat at even moments of time; this function admits at least one local minimum in its domain of definition. It is believed that the mentioned feature is important because it allows to locate the most dangerous areas of threats where the security state probability can be lower then the permissible level. Finally, we introduce an important characteristic of the model, called the relaxation time, by means of which we construct the permitting domain of the security parameters. Also the prospects of the received results application to the problem of finding the optimal values of the security parameters is discussed.

Stereotype Threat in Organizations: An Examination of its Scope, Triggers, and Possible Interventions

OpenAIRE

Kray, Laura J.; Shirako, Aiwa

2009-01-01

This chapter explores stereotype threat in organizational contexts. Building on the understanding that stereotype threat involves concerns about confirming a negative stereotype about one’s group, we begin by elucidating the scope of potential stereotype threat effects in organizations. We first examine the ubiquity of evaluations in organizations, which are at the heart of stereotype threat. Next we specify the potential psychological consequences of stereotype threat on targeted individua...

Minimizing casualties in biological and chemical threats (war and terrorism): the importance of information to the public in a prevention program.

Science.gov (United States)

Noy, Shabtai

2004-01-01

The most effective means of defending against biological or chemical warfare, whether in war or as a result of terror, is the use of primary prevention. The main goal of such a prevention program is to minimize the human loss by reducing the number of casualties (fatalities, physical wounds, and psychological injury). A secondary objective is to prevent the widespread sense of helplessness in the general population. These two aims complement each other. The more the public is active in defending itself, rather than viewing itself as helpless, the lesser the expected number of casualties of any kind. In order to achieve these two goals, educating the civilian population about risk factors and pointing out appropriate defensive strategies is critical. In the absence of an effective prevention program and active participation by the public, there is a high risk for massive numbers of physical and psychological casualties. An essential ingredient of any preventive program, which ultimately may determine the success or failure of all other protective actions, is early, gradual dissemination of information and guidance to the public, so that citizens can become active participants in the program. The public needs to be given information concerning the nature of the threat and effective methods of coping with it, should an unconventional attack occur. Lack of such adaptive behavior (such as wearing protective gear) is likely to bring about vast numbers of physical and psychological casualties. These large numbers may burden the medical, political, and public safety systems beyond their ability to manage. Failure to provide reasonable prevention and effective interventions can lead to a destruction of the social and emotional fabric of individuals and the society. Furthermore, inadequate preparation, education, and communication can result in the development of damaging mistrust of the political and military leadership, disintegration of social and political structures

Bomb Threat Becomes Real News.

Science.gov (United States)

Gastaldo, Evann

1999-01-01

Discusses how the staff of the newspaper at Camarillo High School (California) covered a bomb threat at their school. Describes how they, overnight, conducted interviews, took and developed photographs, produced the layout, and published the newspaper. (RS)

Selected factors associated with achievement of biology preparatory students and their follow-up to higher level biology courses

Science.gov (United States)

Biermann, Carol A.; Sarinsky, Gary B.

This study was undertaken to determine whether a biology preparatory course given at an urban community college was helping students to develop the proper skills and background necessary for them to successfully complete follow-up courses in biology. A group of students who enrolled in a biology preparatory course, and subsequently, a follow-up anatomy and physiology or general biology course (experimental group) was compared to a group of students who should have registered for the preparatory course, but who enrolled directly into the anatomy and physiology or general biology course (control group). It was shown that there was no significant difference in their anatomy and physiology or general biology grades. Furthermore, only 16% of the initial group of preparatory students enrolled in and passed a follow-up biology course. Examination of the preparatory group using discriminant analysis ascertained that mathematics score was the principle discriminator between pass/fail groups. A stepwise multiple regression analysis of the variables explaining the preparatory grade showed that mathematics score, reading score, and type of high school degree explained 33% of the variance. Of the students who did pass the preparatory course and enrolled in a follow-up biology class, their preparatory grade was a good predictor of their achievement (measured by follow-up course grade), as determined by multiple regression.

Reactivity to unpredictable threat as a treatment target for fear-based anxiety disorders.

Science.gov (United States)

Gorka, S M; Lieberman, L; Klumpp, H; Kinney, K L; Kennedy, A E; Ajilore, O; Francis, J; Duffecy, J; Craske, M G; Nathan, J; Langenecker, S; Shankman, S A; Phan, K L

2017-10-01

Heightened reactivity to unpredictable threat (U-threat) is a core individual difference factor underlying fear-based psychopathology. Little is known, however, about whether reactivity to U-threat is a stable marker of fear-based psychopathology or if it is malleable to treatment. The aim of the current study was to address this question by examining differences in reactivity to U-threat within patients before and after 12-weeks of selective serotonin reuptake inhibitors (SSRIs) or cognitive-behavioral therapy (CBT). Participants included patients with principal fear (n = 22) and distress/misery disorders (n = 29), and a group of healthy controls (n = 21) assessed 12-weeks apart. A well-validated threat-of-shock task was used to probe reactivity to predictable (P-) and U-threat and startle eyeblink magnitude was recorded as an index of defensive responding. Across both assessments, individuals with fear-based disorders displayed greater startle magnitude to U-threat relative to healthy controls and distress/misery patients (who did not differ). From pre- to post-treatment, startle magnitude during U-threat decreased only within the fear patients who received CBT. Moreover, within fear patients, the magnitude of decline in startle to U-threat correlated with the magnitude of decline in fear symptoms. For the healthy controls, startle to U-threat across the two time points was highly reliable and stable. Together, these results indicate that startle to U-threat characterizes fear disorder patients and is malleable to treatment with CBT but not SSRIs within fear patients. Startle to U-threat may therefore reflect an objective, psychophysiological indicator of fear disorder status and CBT treatment response.

Measuring Transnational Organized Crime Threats to US National Security

Science.gov (United States)

2016-05-26

interests. These threats were separate from traditional regional or state-centered threats, and included such diverse issues as terrorism, mass migrations ...organizations as examples of TOC; the Sinaloa Cartel, the Yakuza, the Camorra. This conceptual framework leads to the conclusion that the best way to deal

Modeling and Verification of Insider Threats Using Logical Analysis

DEFF Research Database (Denmark)

Kammuller, Florian; Probst, Christian W.

2017-01-01

and use a common trick from the formal verification of security protocols, showing that it is applicable to insider threats. We introduce briefly a three-step process of social explanation, illustrating that it can be applied fruitfully to the characterization of insider threats. We introduce the insider...

Threat Assessment: Do Lone Terrorists Differ from Other Lone Offenders?

OpenAIRE

Diane M. Zierhoffer

2014-01-01

This study evaluates the viability of a threat assessment model developed to calculate the risk of targeted violence as a predictor of violence by potential lone terrorists. There is no profile, to date, which would assist in the identification of a lone terrorist prior to an attack. The threat assessment model developed by Borum, Fein, Vossekuil, and Berglund and described in “Threat Assessment: Defining an approach for evaluating risk of targeted violence” (1999) poses ten questions about t...

Adolescents expressing school massacre threats online: something to be extremely worried about?

Directory of Open Access Journals (Sweden)

Lindberg Nina

2012-12-01

Full Text Available Abstract Background Peer groups identified through the Internet have played an important role in facilitating school shootings. The aim of the present study was to determine whether the adolescents who had expressed a school massacre threat online differed from those who had expressed one offline. Methods A nationwide explorative study was conducted on a group of 77 13- to 18-year-old adolescents sent for adolescent psychiatric evaluation between November 2007 and June 2009 by their general practitioners because they had threatened to carry out a school massacre. According to the referrals and medical files, 17 adolescents expressed the threat online and 60 did so offline. Results The adolescents who expressed their threats online were more likely to be bullied and depressed, had more often pronounced the threat with clear intention and had more often made preparations to carry out the act. In contrast, the adolescents who expressed their threats offline were more likely to have problems with impulse control and had showed delinquent behavior prior to the massacre threats. Conclusions The Finnish adolescents who expressed their massacre threats online could be considered a riskier group than the group who expressed the threats offline. Further studies with larger sample sizes are needed to elucidate this important topic.

Adolescents expressing school massacre threats online: something to be extremely worried about?

Science.gov (United States)

2012-01-01

Background Peer groups identified through the Internet have played an important role in facilitating school shootings. The aim of the present study was to determine whether the adolescents who had expressed a school massacre threat online differed from those who had expressed one offline. Methods A nationwide explorative study was conducted on a group of 77 13- to 18-year-old adolescents sent for adolescent psychiatric evaluation between November 2007 and June 2009 by their general practitioners because they had threatened to carry out a school massacre. According to the referrals and medical files, 17 adolescents expressed the threat online and 60 did so offline. Results The adolescents who expressed their threats online were more likely to be bullied and depressed, had more often pronounced the threat with clear intention and had more often made preparations to carry out the act. In contrast, the adolescents who expressed their threats offline were more likely to have problems with impulse control and had showed delinquent behavior prior to the massacre threats. Conclusions The Finnish adolescents who expressed their massacre threats online could be considered a riskier group than the group who expressed the threats offline. Further studies with larger sample sizes are needed to elucidate this important topic. PMID:23241433

Addressing Stereotype Threat is Critical to Diversity and Inclusion in Organizational Psychology

Directory of Open Access Journals (Sweden)

Bettina J Casad

2016-01-01

Full Text Available Recently researchers have debated the relevance of stereotype threat to the workplace. Critics have argued that stereotype threat is not relevant in high stakes testing such as in personnel selection. We and others argue that stereotype threat is highly relevant in personnel selection, but our review focused on underexplored areas including effects of stereotype threat beyond test performance and the application of brief, low-cost interventions in the workplace. Relevant to the workplace, stereotype threat can reduce domain identification, job engagement, career aspirations, and receptivity to feedback. Stereotype threat has consequences in other relevant domains including leadership, entrepreneurship, negotiations, and competitiveness. Several institutional and individual level intervention strategies that have been field-tested and are easy to implement show promise for practitioners including: addressing environmental cues, valuing diversity, wise feedback, organizational mindsets, reattribution training, reframing the task, values-affirmation, utility-value, belonging, communal goal affordances, interdependent worldviews, and teaching about stereotype threat. This review integrates criticisms and evidence into one accessible source for practitioners and provides recommendations for implementing effective, low-cost interventions in the workplace.

Addressing Stereotype Threat is Critical to Diversity and Inclusion in Organizational Psychology

Science.gov (United States)

Casad, Bettina J.; Bryant, William J.

2016-01-01

Recently researchers have debated the relevance of stereotype threat to the workplace. Critics have argued that stereotype threat is not relevant in high stakes testing such as in personnel selection. We and others argue that stereotype threat is highly relevant in personnel selection, but our review focused on underexplored areas including effects of stereotype threat beyond test performance and the application of brief, low-cost interventions in the workplace. Relevant to the workplace, stereotype threat can reduce domain identification, job engagement, career aspirations, and receptivity to feedback. Stereotype threat has consequences in other relevant domains including leadership, entrepreneurship, negotiations, and competitiveness. Several institutional and individual level intervention strategies that have been field-tested and are easy to implement show promise for practitioners including: addressing environmental cues, valuing diversity, wise feedback, organizational mindsets, reattribution training, reframing the task, values-affirmation, utility-value, belonging, communal goal affordances, interdependent worldviews, and teaching about stereotype threat. This review integrates criticisms and evidence into one accessible source for practitioners and provides recommendations for implementing effective, low-cost interventions in the workplace. PMID:26834681

Hot or cold: is communicating anger or threats more effective in negotiation?

Science.gov (United States)

Sinaceur, Marwan; Van Kleef, Gerben A; Neale, Margaret A; Adam, Hajo; Haag, Christophe

2011-09-01

Is communicating anger or threats more effective in eliciting concessions in negotiation? Recent research has emphasized the effectiveness of anger communication, an emotional strategy. In this article, we argue that anger communication conveys an implied threat, and we document that issuing threats is a more effective negotiation strategy than communicating anger. In 3 computer-mediated negotiation experiments, participants received either angry or threatening messages from a simulated counterpart. Experiment 1 showed that perceptions of threat mediated the effect of anger (vs. a control) on concessions. Experiment 2 showed that (a) threat communication elicited greater concessions than anger communication and (b) poise (being confident and in control of one's own feelings and decisions) ascribed to the counterpart mediated the positive effect of threat compared to anger on concessions. Experiment 3 replicated this positive effect of threat over anger when recipients had an attractive alternative to a negotiated agreement. These findings qualify previous research on anger communication in negotiation. Implications for the understanding of emotion and negotiation are discussed. PsycINFO Database Record (c) 2011 APA, all rights reserved

Addressing Stereotype Threat is Critical to Diversity and Inclusion in Organizational Psychology.

Science.gov (United States)

Casad, Bettina J; Bryant, William J

2016-01-01

Recently researchers have debated the relevance of stereotype threat to the workplace. Critics have argued that stereotype threat is not relevant in high stakes testing such as in personnel selection. We and others argue that stereotype threat is highly relevant in personnel selection, but our review focused on underexplored areas including effects of stereotype threat beyond test performance and the application of brief, low-cost interventions in the workplace. Relevant to the workplace, stereotype threat can reduce domain identification, job engagement, career aspirations, and receptivity to feedback. Stereotype threat has consequences in other relevant domains including leadership, entrepreneurship, negotiations, and competitiveness. Several institutional and individual level intervention strategies that have been field-tested and are easy to implement show promise for practitioners including: addressing environmental cues, valuing diversity, wise feedback, organizational mindsets, reattribution training, reframing the task, values-affirmation, utility-value, belonging, communal goal affordances, interdependent worldviews, and teaching about stereotype threat. This review integrates criticisms and evidence into one accessible source for practitioners and provides recommendations for implementing effective, low-cost interventions in the workplace.

Towards physical principles of biological evolution

Science.gov (United States)

Katsnelson, Mikhail I.; Wolf, Yuri I.; Koonin, Eugene V.

2018-03-01

Biological systems reach organizational complexity that far exceeds the complexity of any known inanimate objects. Biological entities undoubtedly obey the laws of quantum physics and statistical mechanics. However, is modern physics sufficient to adequately describe, model and explain the evolution of biological complexity? Detailed parallels have been drawn between statistical thermodynamics and the population-genetic theory of biological evolution. Based on these parallels, we outline new perspectives on biological innovation and major transitions in evolution, and introduce a biological equivalent of thermodynamic potential that reflects the innovation propensity of an evolving population. Deep analogies have been suggested to also exist between the properties of biological entities and processes, and those of frustrated states in physics, such as glasses. Such systems are characterized by frustration whereby local state with minimal free energy conflict with the global minimum, resulting in ‘emergent phenomena’. We extend such analogies by examining frustration-type phenomena, such as conflicts between different levels of selection, in biological evolution. These frustration effects appear to drive the evolution of biological complexity. We further address evolution in multidimensional fitness landscapes from the point of view of percolation theory and suggest that percolation at level above the critical threshold dictates the tree-like evolution of complex organisms. Taken together, these multiple connections between fundamental processes in physics and biology imply that construction of a meaningful physical theory of biological evolution might not be a futile effort. However, it is unrealistic to expect that such a theory can be created in one scoop; if it ever comes to being, this can only happen through integration of multiple physical models of evolutionary processes. Furthermore, the existing framework of theoretical physics is unlikely to suffice