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Sample records for multichannel intraluminal impedance

  1. Multichannel intraluminal impedance monitoring in the evaluation of patients with non-obstructive Dysphagia

    NARCIS (Netherlands)

    Conchillo, José M.; Nguyen, Nam Q.; Samsom, Melvin; Holloway, Richard H.; Smout, André J. P. M.

    2005-01-01

    BACKGROUND: Non-obstructive dysphagia (NOD) often poses diagnostic problems. The aim of this study was to evaluate the value of the addition of multichannel intraluminal impedance (MII) recording to esophageal manometry in the work-up of patients with NOD. METHODS: A total of 40 consecutive patients

  2. Multichannel intraluminal impedance monitoring in the evaluation of patients with non-obstructive dysphagia

    NARCIS (Netherlands)

    Conchillo, JM; Nguyen, NQ; Samsom, M; Holloway, RH; Smout, AJPM

    2005-01-01

    BACKGROUND: Non-obstructive dysphagia (NOD) often poses diagnostic problems. The aim of this study was to evaluate the value of the addition of multichannel intraluminal impedance (MII) recording to esophageal manometry in the work-up of patients with NOD. METHODS: A total of 40 consecutive patients

  3. An audit of combined multichannel intraluminal impedance manometry in the assessment of dysphagia.

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    Burgess, Nicholas G; Wyeth, John W

    2011-04-01

    Multichannel Intraluminal Impedance (MII) Monitoring is a method of examining oesophageal bolus transit without the need for radiation. In combination with oesophageal manometry it allows correlation of bolus transit with peristaltic activity. The clinical application of impedance manometry is still being refined. This audit looked to examine whether impedance manometry had advantages over standard manometry in assessment of patients with dysphagia. 41 patients with the presenting symptom of dysphagia were assessed by combined MII and oesophageal manometry at a Wellington Hospital between February 2008 and December 2009. Each underwent manometry and MII using standardised techniques. Achalasia was diagnosed in 23 patients (56.1%), Ineffective oesophageal motility (IEM) in 5 patients (12.2%), Diffuse oesophageal Spasm (DES) in 7 patients (17.1%), and Nutcracker oesophagus in 2 patients (4.9%). 4 patients had normal manometry studies (9.8%). All patients with achalasia, IEM, and DES had abnormal bolus transit. All patients with normal manometry had abnormal bolus transit. Both patients with nutcracker oesophagus had normal bolus transit. 4 patients with achalasia had undergone previous Hellers myotomy. Two of these patients (50.0%) now had normal LES relaxation pressures, but all four still had abnormal oesophageal peristalsis and abnormal bolus transit. Multichannel Intraluminal Impedance manometry has advantages over standard manometry in characterising the physiological abnormalities associated with dysphagia. Patients in this study had severe defects including achalasia where bolus transit was invariably poor meaning little further information was gained. Extension of this study to include a wider group of patients with dysphagia may yield different results. © 2011 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd.

  4. COMBINED 24-HOURS ESOPHAGEAL PH MONITORING AND MULTICHANNEL INTRALUMINAL IMPEDANCE FOR COMPARISON OF GASTROESOPHAGEAL REFLUX IN CHILDREN WITH TYPICAL VERSUS ATYPICAL SYMPTOMS OF GASTROESOPHAGEAL REFLUX DISEASE.

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    Dehghani, Seyed Mohsen; Taghavi, Seyed Alireza; Javaherizadeh, Hazhir; Nasri, Maryam

    2016-01-01

    - Gastroesophageal reflux disease is the most common esophageal disorder in pediatrics. - The aim of this study was to compare reflux parameters of typical and atypical symptoms of gastroesophageal reflux disease using 24-hour esophageal pH monitoring and multichannel intraluminal impedance in pediatric population. - In this prospective study, 43 patients aged less than 18 year with suspected gastroesophageal reflux disease were enrolled. The patients were divided into two groups based on the main presenting symptoms (typical versus atypical). Twenty four-hour pH monitoring and multichannel intraluminal impedance were performed in all the patients for comparing these two group regarding association of symptoms and reflux. Number of refluxes, pH related reflux, total reflux time, reflux more than 5 minutes, longest time of the reflux, lowest pH at reflux, reflux index were recorded and compared. Data comparison was done using SPSS. - The mean age of the patients was 5.7±3.4 years and 65.1% were male. Out of 43 patients 24 cases had typical symptoms and 19 had atypical symptoms. The mean reflux events detected by multichannel intraluminal impedance was more than mean reflux events detected by pH monitoring (308.4±115.8 vs 69.7±66.6) with P value of 0.037, which is statistically significant. The mean symptom index and symptom association probability were 35.01% ± 20.78% and 86.42% ± 25.79%, respectively in multichannel intraluminal impedance versus 12.73% ± 12.48% and 45.16% ± 42.29% in pH monitoring (P value reflux was 46.26±47.16 and 30.9±22.09 for atypical and typical symptoms respectively. The mean symptom index was 18.12% ± 13.101% and 8.30% ± 10.301% in atypical and typical symptoms respectively (P=0.034). Bolus clearance was longer in atypical symptoms compared typical symptoms(Preflux was found in children with atypical symptoms of reflux. Longer duration of bolus clearance was found in group with atypical symptoms of reflux.

  5. CHRONIC COUGH AND DENTAL EROSIONS IN A CHILD WITH GASTROESOPHAGEAL REFLUX EVALUATED BY PH-METRY ASSOCIATED WITH MULTICHANNEL INTRALUMINAL IMPEDANCE

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    Felicia GALOŞ

    2013-12-01

    Full Text Available The clinical manifestations of the gastroesophageal reflux disease (GERD are multiple and heterogeneous, differing according to age and individual susceptibility. The relationship between respiratory manifestations and the gastroesophageal reflux (GER in children is a contro‑ versial topic on: proving or refuting either cause or effect, with special stress on the most important symptom – cough. Dental erosions can be GERD-related, especially in the case of infants or of neurologically-impaired children. The case of a 4 year and 8 month-old child with gastroeso‑ phageal reflux, with typical (chronic vomiting and atypi‑ cal (chronic cough, dental erosions digestive manifestations, a diagnosis established by pH-metry asso‑ ciated with multichannel intraluminal impedance, will be discussed in the study.

  6. Impedancia esofágica intraluminal de canal múltiple: una nueva frontera en motilidad Multichannel intraluminal esophageal impedance: A new frotier in motility

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    F. de la Morena

    2008-02-01

    Full Text Available La impedancia esofágica multicanal constituye una de las más recientes herramientas diagnósticas aplicadas a la evaluación de la enfermedad por reflujo gastroesofágico. Esta técnica se basa en la monitorización continua de la conductividad eléctrica en un medio, en este caso el esófago, a través de electrodos situados en la longitud de una sonda, y en los cambios que un elemento como el bolo alimentario puede producir en dicha variable. De esta técnica se derivan nuevas perspectivas en la exploración de la función esofágica y de la enfermedad por reflujo gastroesofágico, hasta ahora sólo cuantificable de forma indirecta por las fluctuaciones generadas por los cambios en el pH del reflujo ácido. Presentamos el caso de una paciente con tos persistente evaluada con este procedimiento, en quien se demostró la presencia de reflujo gastroesofágico débilmente ácido que no pudo ser demostrado previamente con otras exploraciones, y de cómo la impedancia descartó la asociación entre este síntoma y el reflujo no ácido.Multichannel intraluminal impedance is a new technique for evaluating esophageal function and gastroesophageal reflux disease (GERD. This technique relies on the monitoring of electric conductivity in the esophagus though electrodes, and on changes developing in this variable as a result of bolus passage. The proximal distribution and duration of non-acid reflux events can now be quantified, and combined manometry defines the effectiveness of esophageal body function, until now only indirectly evaluated with pH changes. We discuss the case of a woman with persistent cough in whom intraesophageal multichannel impedance demostrates a minor acid reflux that could not be demonstrated with other diagnostic methods previously, and how this technique excludes any association between cough and non-acid reflux.

  7. Physiological analysis of the effects of rikkunshito on acid and non-acid gastroesophageal reflux using pH-multichannel intraluminal impedance monitoring.

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    Kawahara, Hisayoshi; Tazuke, Yuko; Soh, Hideki; Yoneda, Akihiro; Fukuzawa, Masahiro

    2014-09-01

    To clarify the effects of rikkunshito on acid reflux, non-acid reflux, and esophageal clearance in patients with gastroesophageal reflux disease (GERD). We enrolled seven patients with vomiting and/or stridor (median 6 years; 1 month-17 years), with a percent total time of esophageal pH reflux index) over 4.0%. Rikkunshito (TJ-43; Tsumura Co, Tokyo, Japan) was given in three divided doses before meals. We retrospectively investigated its efficacy using pH-multichannel intraluminal impedance before and 7 (6-10) days after starting treatment. Statistical analyses were conducted using Wilcoxon signed-rank test. In the pH analyses alone, the median number of acid reflux episodes >5 min (14 versus 10, p = 0.046) and median acid-clearance time (184 versus 134 s, p = 0.03) decreased significantly, although median decrease in reflux index did not reach significance (16.0 versus 17.9%, p = 0.06). In the combined impedance and pH analyses, the median number (36 versus 36, p = 0.03) and median duration (1.9 versus 1.1%, p = 0.046) of acid reflux decreased significantly; non-acid reflux and bolus clearance time did not change. Rikkunshito effectively reduced acid reflux, but not esophageal clearance, in patients with GERD.

  8. Esophageal acid exposure decreases intraluminal baseline impedance levels

    NARCIS (Netherlands)

    Kessing, Boudewijn F.; Bredenoord, Albert J.; Weijenborg, Pim W.; Hemmink, Gerrit J. M.; Loots, Clara M.; Smout, A. J. P. M.

    2011-01-01

    Intraluminal baseline impedance levels are determined by the conductivity of the esophageal wall and can be decreased in gastroesophageal reflux disease (GERD) patients. The aim of this study was to investigate the baseline impedance in GERD patients, on and off proton pump inhibitor (PPI), and in

  9. Esophageal intraluminal baseline impedance is associated with severity of acid reflux and epithelial structural abnormalities in patients with gastroesophageal reflux disease.

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    Zhong, Chanjuan; Duan, Liping; Wang, Kun; Xu, Zhijie; Ge, Ying; Yang, Changqing; Han, Yajing

    2013-05-01

    The esophageal intraluminal baseline impedance may be used to evaluate the status of mucosa integrity. Esophageal acid exposure decreases the baseline impedance. We aimed to compare baseline impedance in patients with various reflux events and with different acid-related parameters, and investigate the relationships between epithelial histopathologic abnormalities and baseline impedance. A total of 229 GERD patients and 34 controls underwent 24-h multichannel intraluminal impedance and pH monitoring (MII-pH monitoring), gastroendoscopy, and completed a GERD questionnaire (GerdQ). We quantified epithelial intercellular spaces (ICSs) and expression of tight junction (TJ) proteins by histologic techniques. Mean baseline values in reflux esophagitis (RE) (1752 ± 1018 Ω) and non-erosive reflux disease (NERD) (2640 ± 1143 Ω) were significantly lower than in controls (3360 ± 1258 Ω; p acid reflux group (2510 ± 1239 Ω) and mixed acid/weakly acidic reflux group (2393 ± 1009 Ω) were much lower than in controls (3360 ± 1258 Ω; p = 0.020 and p acid exposure time (AET) (r = -0.41, p acid reflux events and with longer AET have low baseline impedance. Baseline values are correlated with esophageal mucosal histopathologic changes such as dilated ICS and TJ alteration.

  10. Intraesophageal pressure recording improves the detection of cough during multichannel intraluminal impedance testing in children.

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    Rosen, Rachel; Amirault, Janine; Giligan, Emily; Khatwa, Umakanth; Nurko, Samuel

    2014-01-01

    One of the primary reasons for referral for reflux testing is to correlate reflux events with symptoms such as cough. Adult studies have suggested that symptom recording is flawed and pediatricians feel this is an even more significant problem because there may be errors in both parental and patient reports. We hypothesize that intraesophageal pressure recording (IEPR) provides an objective method to identify coughs during reflux testing in children. We recruited 20 children undergoing multichannel intraluminal impedance with pH (pH-MII) testing for the evaluation of cough. We placed simultaneous intraesophageal pressure and pH-MII catheters. Tracings were blindly scored by 2 observers without knowledge of patient/parent symptom report. After the blinded scoring, patient/parent report of symptoms was recorded. Ninety-four percent of all coughs were detected by IEPR and only 48% of all coughs were reported by patients/parents. The mean time from the IEPR cough to the patient/parent cough was 11±16 seconds. Using IEPR as the criterion standard for the detection of cough, the sensitivity of patient report for the detection of cough is 46%. Using varying symptom windows because of the increased precision of IEPR, the number of patients with a positive symptom index could be reduced from 30% to 0%, preventing children from being falsely categorized as having reflux-related lung disease. Parental and patient symptom recording in children is inadequate for making the diagnosis of reflux-related lung disease. If patients undergo pH-MII testing for reflux-related cough, IEPR should become the new standard by which to correlate reflux with cough.

  11. Correlation of Gastroesophageal reflux disease Assessment Symptom Questionnaire to impedance-pH measurements in children.

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    Prachuapthunyachart, Sittichoke; Jarasvaraparn, Chaowapong; Gremse, David A

    2017-01-01

    Esophageal multichannel intraluminal impedance-pH monitoring has become one of the preferred tests to correlate observed reflux-like behaviors with esophageal reflux events. The Gastroesophageal reflux disease Assessment Symptom Questionnaire is a validated tool used to distinguish infants with gastroesophageal reflux disease from healthy children. The aim of this study was to determine whether the Gastroesophageal reflux disease Assessment Symptom Questionnaire composite symptom scores and individual symptom scores correlate with outcomes in esophageal multichannel intraluminal impedance-pH monitoring. A total of 26 patients with gastroesophageal reflux disease-associated symptoms, aged 0-2 years, for whom both esophageal multichannel intraluminal impedance-pH monitoring and Gastroesophageal reflux disease Assessment Symptom Questionnaire survey results were available were included in the study. Gastroesophageal reflux disease Assessment Symptom Questionnaire score data were collected from a 7-day recall of parent's responses about the frequency and severity of gastroesophageal reflux disease symptoms, which determined the individual symptom scores. The composite symptom scores is the sum of all individual symptom scores. Multichannel intraluminal impedance-pH study results were compared to Gastroesophageal reflux disease Assessment Symptom Questionnaire data using Pearson correlation. Among 26 patients, a total number of 2817 (1700 acid and 1117 non-acid) reflux episodes and 845 clinical reflux behaviors were recorded. There were significant correlations between the reflux index and the individual symptom scores for coughing/gagging/choking (r 2 = 0.2842, p = 0.005), the impedance score and individual symptom scores for coughing/gagging/choking (r 2 = 0.2482, p = 0.009), the reflux symptom index for acid reflux-related coughing/gagging/choking and the individual symptom scores for coughing/gagging/choking (r 2 = 0.1900, p = 0.026), the impedance score and

  12. Small volume acid reflux in gastroesophageal reflux disease patients with hiatal hernia is only detectable by pH-metry but not by multichannel intraluminal impedance.

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    Weigt, J; Malfertheiner, P

    2013-07-01

    Until now, it is uncertain if the so-called pH-only reflux episodes that consist of a pH drop without evidence of retrograde bolus movement in multichannel intraluminal impedance (MII) represent reflux episodes or artifacts. Hiatal hernia (HH) may allow reflux of small volumes to occur that can be detected by pH-metry but not by MII. The aim was to search for a mechanism that can explain pH-only reflux, 20 patients (12 females and 8 males, median age 52 years, interquartile range [IQR]: 40.5-60.75 years) were investigated with MII-pH off PPI. Impedance and pH-metry data were analyzed separately. The differences in detection rate of acid reflux between pH-metry and MII were correlated with the presence of HH. In an in vitro experiment, MII-pH probes were flushed with citric acid in plastic tubes of different size with capillary diameter and diameters of 2.5 mm and 4.5 mm, while recording pH values and impedance. HH was present in six patients and absent in 14 patients. In patients with HH in comparison with patients with absent HH, the difference of acid reflux detection between pH-metry and MII is significantly higher (70%, IQR: 15-88% and 3.6%, IQR: 0-31%, respectively). In vitro all simulated reflux lead to a fall in pH whereas a corresponding decrease in impedance was only recognizable in the 4.5-mm plastic tubes. Acid reflux episodes in patients with HH are more frequently detected by pH-metry than by MII. Small volume reflux that does not lead to a decrease in impedance is the likely explanation for this phenomenon. © 2012 Copyright the Authors. Journal compilation © 2012, Wiley Periodicals, Inc. and the International Society for Diseases of the Esophagus.

  13. Gastro-oesophageal reflux in patients with chronic rhino-sinusitis investigated with multichannel impedance - pH monitoring.

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    Katle, E J; Hatlebakk, J G; Grimstad, T; Kvaløy, J T; Steinsvåg, S K

    2017-03-01

    The pathophysiology of chronic rhinosinusitis (CRS) is unclear. It has been discussed for decades whether gastro-oesophageal reflux (GOR) may be a contributing factor for some patients. The aim of the present study was to evaluate the level of GOR in an unselected group of patients with CRS using multichannel impedance-pH monitoring. Consecutive patients with CRS diagnosed using the EPOS2012 criteria, completed questionnaires on GOR symptoms and were offered 24-h multichannel intraluminal impedance (MII)-pH monitoring. The results were compared with a group of healthy controls. Forty-six patients completed MII-pH-monitoring and were compared with 45 control subjects, with comparable age and gender distributions. The median number of reflux episodes in the patients was 56.5 compared with 33 in controls, while, the numbers of proximal reflux episodes was 27.5 versus 3, respectively. Thirty nine patients had abnormal pH-impedance recordings compared with five controls. The CRS patients had significantly higher incidences of gastro-oesophageal reflux compared with asymptomatic controls. The results of this study suggest that GOR may be a causative or contributing factor of CRS.

  14. Tailored therapy guided by multichannel intraluminal impedance pH monitoring for refractory non-erosive reflux disease.

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    Ranaldo, Nunzio; Losurdo, Giuseppe; Iannone, Andrea; Principi, Mariabeatrice; Barone, Michele; De Carne, Massimo; Ierardi, Enzo; Di Leo, Alfredo

    2017-09-07

    A relevant percentage of non-erosive reflux disease (NERD) is refractory to proton pump inhibitors (PPIs) treatment. Multichannel intraluminal impedance pH (MII-pH) monitoring should give useful pathophysiological information about refractoriness. Therefore, our aim was to assess whether this technique could be useful to guide a 'tailored' therapy in refractory NERD. We retrospectively recruited NERD patients undergoing MII-pH monitoring for unsuccessful treatment. All patients had undergone upper endoscopy, and those with erosive esophagitis were excluded. No patient received PPI during MII-pH monitoring. Subjects were subgrouped into three categories: acid reflux, non-acid reflux and functional heartburn. MII-pH-guided therapy was performed for 4 weeks as follows: patients with acid reflux received PPI at double dose, patients with non-acid reflux PPI at full dose plus alginate four times a day and patients with functional heartburn levosulpiride 75 mg per day. A visual analog scale (VAS) ranging from 0 to 100 mm was administered before and after such tailored therapy to evaluate overall symptoms. Responders were defined by VAS improvement of at least 40%. Sixty-nine patients with refractory NERD were selected (female-male ratio 43 : 26, mean age 47.6±15.2 years). Overall effectiveness of tailored therapy was 84% without statistical difference among subgroups (88.5% acid reflux, 92% non-acid reflux, 66.6% functional heartburn; P=0.06). Univariate analysis showed that therapy failure directly correlated with functional heartburn diagnosis (OR=4.60) and suggested a trend toward a negative correlation with smoking and a positive one with nausea. However, at multivariate analysis, these parameters were not significant. Functional heartburn experienced a lower median percent VAS reduction than acid reflux (52.5% versus 66.6%, Pacid reflux (66.6%). In conclusion, a tailored approach to refractory NERD, guided by MII-pH monitoring, demonstrated to be effective

  15. Esophageal multichannel intraluminal impedance and pH-testing in the study of apparent life threatening episode incidents in infants

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    Javier Blasco-Alonso

    2014-03-01

    Full Text Available Introduction: The conventional 24-hour pH monitoring is the gold standard for the diagnosis of gastro-esophageal reflux (GER, a possible cause of Apparent Life Threatening Episodes (ALTE. However, multichannel intraluminal impedance (MII may provide advantages. Objectives: Comparison of the results of MII and pH monitoring in patients undergoing MII-pH monitoring in the 3-year study period because of having suffered from ALTE. Material and methods: Prospective study of MII-pH monitoring performed in our unit to infants 5 min per patient and clearance of 1.20 (IQ: 0.70-2.20 min/reflux. With pH monitoring analysis, 14 children (35.9 % could have been diagnosed as GER (8 mild, 4 moderate and 2 severe based on the classical criteria. MII identified a total of 8,895 events; only 3,219 among them were refluxes, with a median of 75 (IQ: 54-111 per patient, 1.30 (IQ: 1.3-2.6 episodes/hour. With MII-pH monitoring combination there were 21.60 (SD 15.21 acid reflux episodes, 67.33 weekly acid (SD 32.09 and 3.34 (SD 7.23 non-acid, being finally diagnosed 33 patients as GER. Conclusions: The association of pH monitoring and MII provides additional information that improves GER diagnostic performance without posing any additional risk to the infant patient. The non-acid/weekly acid refluxes, not detected by pH monitoring, account for a high percentage of episodes, this may have diagnostic and therapeutic significance, especially in infants. Further studies are needed to assess the normality of MMI in pediatric patients.

  16. Esophageal intraluminal baseline impedance differentiates gastroesophageal reflux disease from functional heartburn.

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    Kandulski, Arne; Weigt, Jochen; Caro, Carlos; Jechorek, Doerthe; Wex, Thomas; Malfertheiner, Peter

    2015-06-01

    Mucosal integrity can be assessed in patients with gastroesophageal reflux disease (GERD) by measuring intraluminal baseline impedance (BI). However, it is not clear whether BI is abnormal in patients with functional heartburn (FH), or can be used to distinguish them from patients with GERD. We compared differences in BI between patients with FH vs GERD. We performed a prospective study of 52 patients (16 men; mean age, 55 y; range, 23-78 y) seen at a tertiary university hospital from February 2009 through December 2012. Thirty-five patients had GERD (19 had nonerosive reflux disease [NERD], 16 had erosive reflux disease [ERD]) and 17 had FH. All patients discontinued proton pump inhibitor therapy and then underwent esophagogastroduodenoscopy and multichannel intraluminal impedance and pH monitoring. BI was assessed at 3, 5, 7, 9, 15, and 17 cm proximal to the lower esophageal sphincter in recumbent patients. Biopsy specimens were taken from 3 cm above the gastroesophageal junction; histology analysis was performed to identify and semiquantitatively score (scale, 0-3) dilated intercellular spaces. Baseline impedance in the distal esophagus was significantly lower in patients with NERD or erosive reflux disease (ERD) than FH (P = .0006). At a cut-off value of less than 2100 Ω, BI measurements identified patients with GERD with 78% sensitivity and 71% specificity, with positive and negative predictive values of 75%. Also in the proximal esophagus, reduced levels of BI levels were found only in patients with ERD. There were negative correlations between level of BI and acid exposure time (r = -0.45; P = .0008), number of acidic reflux episodes (r = -0.45; P = .001), and proximal extent (r = -0.40; P = .004). Biopsy specimens from patients with NERD or ERD had significant increases in dilation of intercellular spaces, compared with those from patients with FH; there was an inverse association between dilated intercellular spaces and BI in the distal esophagus

  17. Diagnostic value of combined esophageal multi-channel intraluminal impedance and pH monitoring for gastroesophageal reflux in critically ill patients

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    Yi JIN

    2016-06-01

    Full Text Available Objective  To compare the diagnostic value of using 24-hour combined esophageal multichannel intraluminal impedance and pH monitoring (MII-pH in the diagnosis of gastro-esophageal reflux (GER and pH monitoring alone in critically ill patients. Methods  A prospective observational study was performed including 116 critically ill adult patients admitted to ICU of Peking Haidian Hospital from Jul. 2013 to Dec. 2014. All the patients underwent 24-hour combined MⅡ-pH monitoring. GER episodes were recorded and its pH was recorded (acidic, weakly acidic and weakly alkaline and its composition was recorded (liquid, mixed and gas reflux. The results of the MⅡ-pH and the pH were monitored and compared. The demographic characteristics and clinical information were recorded. Results  MⅡ-pH was monitored for 5024 episodes of GER in 115 of 116(99.1% patients, with a mean of 43.28±3.96 episodes per patient (median, 34 episodes; range, 0-196 episodes. The pH monitoring detected 1868 episodes (100% acid in only 54 of 116(46.6% patients, with a mean of 7.66±1.65 episodes per patient (median, 0 episodes; range, 0-81 episodes. The number of episode of all reflux and liquid reflux diagnosed by pH monitoring alone was less than those diagnosed by MⅡ-pH monitoring (P=0.000, and there was no correlation in the episodes number of all reflux and liquid reflux between the two techniques (r=0.119, 0.231. Only a moderate correlation was found in the number of episodes of acidic reflux between the two techniques (r=0.656. Conclusion  MⅡ-pH monitoring is more sensitive than pH monitoring alone for establishing the diagnosis of GER. DOI: 10.11855/j.issn.0577-7402.2016.05.12

  18. The role of combined 24-h multichannel intraluminal impedance-pH monitoring in the evaluation of children with gastrointestinal symptoms suggesting gastro-esophageal reflux disease.

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    Hojsak, I; Ivković, L; Trbojević, T; Pavić, I; Jadrešin, O; Mišak, Z; Kolaček, S

    2016-10-01

    The aim of this study was to determine the role of multichannel intraluminal impedance-pH (pH-MII) monitoring in the diagnosis of gastro-esophageal reflux disease (GERD) in children who presented with gastrointestinal (GI) symptoms in comparison with the results of pH-metry alone and endoscopy. All children who underwent pH-MII monitoring due to GI symptoms, suggestive of GERD, from October 2013 to October 2015 in Children's Hospital Zagreb, were retrospectively enrolled in the study. The cohort was divided into three groups according to age - group 1: children Gastro-esophageal reflux disease was determined in 44 of 133 patients (33.1%) by pH-MII and only in 21 of 133 patients (15.8%) by pH-metry alone. Endoscopy was performed in 77 (57.9%) children and esophagitis was found in 32/77 (41.6%). The finding of esophagitis significantly correlated with the number of total reflux episodes (coef. 0.42, p reflux episodes detected by pH-MII; but, no correlation was found to reflux episodes detected by pH-metry alone (coef. 0.21, p = 0.07). Compared with pH-metry alone, pH-MII performed significantly better in the detection of GERD in all age groups. On the basis of our data, pH-MII had a strong correlation with endoscopically confirmed esophagitis. © 2016 John Wiley & Sons Ltd.

  19. Laparoscopic Nissen fundoplication mainly reduces the volume of acid reflux and potentially improves mucosal integrity up to the middle esophagus in neurologically impaired children detected by esophageal combined pH-multichannel intraluminal impedance measurements.

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    Fukahori, Suguru; Yagi, Minoru; Ishii, Shinji; Asagiri, Kimio; Saikusa, Nobuyuki; Hashizume, Naoki; Yoshida, Motomu; Masui, Daisuke; Sakamoto, Saki; Tsuruhisa, Shihori; Kurahachi, Tomohiro; Tanaka, Yoshiaki

    2016-08-01

    The aim of this study was to evaluate detailed changes of gastroesophageal reflux disease (GERD) in children before and after laparoscopic Nissen fundoplication (LNF) utilizing esophageal combined pH-multichannel intraluminal impedance (pH/MII) measurements. Thirteen patients with neurological impairment, who received laparoscopic Nissen fundoplication (LNF) owing to refractory pathological GERD, were enrolled in this study. 24h pH/MII was conducted in all patients before and one year after LNF. Each parameter of the pH/MII was evaluated and compared each other. Both the mean pH index and bolus exposure index after LNF were significantly lower than those before LNF. The mean numbers of total and nonacid reflux episodes after LNF were significantly lower than those before LNF. The mean numbers of total, acid and nonacid proximal reflux episodes after LNF were significantly lower than those before LNF. The mean baseline impedance values from Z3 to Z6 after LNF were significantly higher than those before LNF. The present study provides new insights into the effects of LNF in pediatric patients, which prevents mainly acid reflux episodes from rising to the proximal esophagus, and is expected to improve the mucosal integrity up to the middle esophagus. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Acid and nonacid gastroesophageal reflux after single anastomosis gastric bypass. An objective assessment using 24-hour multichannel intraluminal impedance-pH metry.

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    Doulami, Georgia; Triantafyllou, Stamatina; Albanopoulos, Konstantinos; Natoudi, Maria; Zografos, Georgios; Theodorou, Dimitrios

    2018-04-01

    Single anastomosis gastric bypass (SaGB) was introduced in 2001 as an alternative to "loop" gastric bypass. It was considered as a procedure that would eliminate alkaline reflux and associated esophagitis. Existing evidence about the postoperative incidence of gastroesophageal reflux (GERD) after SaGB is based on studies using symptom questionnaires. The aim of our study was to evaluate GERD 12 months after SaGB by using 24-hour multichannel intraluminal impedance pH metry (24-h MIIpH). Surgical department of a university hospital METHODS: Morbidly obese candidates for SaGB underwent 24-hour MIIpH prior and 12 months after their bariatric procedure. There were 11 patients included in this prospective study. Results of 24-hour MIIpH revealed that DeMeester score (40.48 versus 24.16, P = .339) had an increasing trend 12 months after SaGB. Acid reflux episodes decreased, whereas nonacid reflux episodes increased postoperatively, both in proximal and distal esophagus. Total median bolus clearance time and acid clearance time increased. De novo GERD developed in 2 patients (28.6%) and worsening of already existing GERD developed in all patients with preoperative evidence of GERD. The use of symptom questionnaires to assess postoperative GERD after SaGB may not accurately depict the real image. Twenty-four-hour MIIpH in 12 months after SaGB revealed an increase of total number of nonacid reflux episodes and a decrease of total number of acid reflux episodes, with longer duration of each acid reflux episode. Close postoperative follow-up with reflux testing and possibly endoscopy could eliminate the risk of complicated GERD. Copyright © 2017 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

  1. Diagnosis and Anti-Reflux Therapy for GERD with Respiratory Symptoms: A Study Using Multichannel Intraluminal Impedance-pH Monitoring.

    Directory of Open Access Journals (Sweden)

    Chao Zhang

    Full Text Available Respiratory symptoms are often associated with gastroesophageal reflux disease (GERD. Although the role of multichannel intraluminal impedance-pH (MII-pH monitoring in GERD is clear, little is known regarding the characteristics of patients with respiratory symptoms based on MII-pH monitoring and anti-reflux therapy. We evaluated a cohort of GERD patients to identify the MII-pH parameters of GERD-related respiratory symptoms and to assess the anti-reflux therapy outcomes.We undertook a prospective study of patients who were referred for GERD evaluation from January 2011 to January 2012. One hundred ninety-five patients underwent MII-pH monitoring and esophageal manometry, and one hundred sixty-five patients underwent invasive anti-reflux therapy that included laparoscopic Toupet fundoplication (LTF and the Stretta procedure. The patient characteristics and MII-pH parameters were analyzed, and the symptom scores were assessed at baseline and at 1- and 3-year follow-up evaluations.Of the 195 patients, 96 (49.2% exhibited respiratory symptoms and significantly more reflux episodes (70.7±29.3 than patients without respiratory symptoms (64.7±24.4, p = 0.044 based on the MII-pH monitoring results. Moreover, the group of patients with respiratory symptoms exhibited more proximal reflux episodes (35.2±21.3 than the non-respiratory symptomatic group (28.3±17.9, p = 0.013. One hundred twenty-five patients following the Stretta procedure (n = 60, 31 with respiratory symptoms or LTF (n = 65, 35 with respiratory symptoms completed the designated 3-year follow-up period and were included in the final analysis. The symptom scores after anti-reflux therapy all decreased relative to the corresponding baseline values (p0.05. However, LTF significantly reduced the recurrence (re-operation rate compared with the Stretta procedure (0 vs. 19.4%, p = 0.006.MII-pH monitoring effectively detected respiratory-related predictive parameters, including total

  2. Multi-channel electrical impedance tomography for regional tissue hydration monitoring

    International Nuclear Information System (INIS)

    Chen, Xiaohui; Kao, Tzu-Jen; Ashe, Jeffrey M; Boverman, Gregory; Sabatini, James E; Davenport, David M

    2014-01-01

    Poor assessment of hydration status during hemodialysis can lead to under- or over-hydration in patients with consequences of increased morbidity and mortality. In current practice, fluid management is largely based on clinical assessments to estimate dry weight (normal hydration body weight). However, hemodialysis patients usually have co-morbidities that can make the signs of fluid status ambiguous. Therefore, achieving normal hydration status remains a major challenge for hemodialysis therapy. Electrical impedance technology has emerged as a promising method for hydration monitoring due to its non-invasive nature, low cost and ease-of-use. Conventional electrical impedance-based hydration monitoring systems employ single-channel current excitation (either 2-electrode or 4-electrode methods) to perturb and extract averaged impedance from bulk tissue and use generalized models from large populations to derive hydration estimates. In the present study, a prototype, single-frequency electrical impedance tomography (EIT) system with simultaneous multi-channel current excitation was used to enable regional hydration change detection. We demonstrated the capability to detect a difference in daily impedance change between left leg and right leg in healthy human subjects, who wore a compression sock only on one leg to reduce daily gravitational fluid accumulation. The impedance difference corresponded well with the difference of lower leg volume change between left leg and right leg measured by volumetry, which on average is ∼35 ml, accounting for 0.7% of the lower leg volume. We have demonstrated the feasibility of using multi-channel EIT to extract hydration information in different tissue layers with minimal skin interference. Our simultaneous, multi-channel current excitation approach provides an effective method to separate electrode contact impedance and skin condition artifacts from hydration signals. The prototype system has the potential to be used in

  3. Multi-channel electrical impedance tomography for regional tissue hydration monitoring.

    Science.gov (United States)

    Chen, Xiaohui; Kao, Tzu-Jen; Ashe, Jeffrey M; Boverman, Gregory; Sabatini, James E; Davenport, David M

    2014-06-01

    Poor assessment of hydration status during hemodialysis can lead to under- or over-hydration in patients with consequences of increased morbidity and mortality. In current practice, fluid management is largely based on clinical assessments to estimate dry weight (normal hydration body weight). However, hemodialysis patients usually have co-morbidities that can make the signs of fluid status ambiguous. Therefore, achieving normal hydration status remains a major challenge for hemodialysis therapy. Electrical impedance technology has emerged as a promising method for hydration monitoring due to its non-invasive nature, low cost and ease-of-use. Conventional electrical impedance-based hydration monitoring systems employ single-channel current excitation (either 2-electrode or 4-electrode methods) to perturb and extract averaged impedance from bulk tissue and use generalized models from large populations to derive hydration estimates. In the present study, a prototype, single-frequency electrical impedance tomography (EIT) system with simultaneous multi-channel current excitation was used to enable regional hydration change detection. We demonstrated the capability to detect a difference in daily impedance change between left leg and right leg in healthy human subjects, who wore a compression sock only on one leg to reduce daily gravitational fluid accumulation. The impedance difference corresponded well with the difference of lower leg volume change between left leg and right leg measured by volumetry, which on average is ~35 ml, accounting for 0.7% of the lower leg volume. We have demonstrated the feasibility of using multi-channel EIT to extract hydration information in different tissue layers with minimal skin interference. Our simultaneous, multi-channel current excitation approach provides an effective method to separate electrode contact impedance and skin condition artifacts from hydration signals. The prototype system has the potential to be used in clinical

  4. Patterns of gas and liquid reflux during transient lower oesophageal sphincter relaxation: a study using intraluminal electrical impedance

    OpenAIRE

    Sifrim, D; Silny, J; Holloway, R; Janssens, J

    1999-01-01

    Background—Belching has been proposed as a major mechanism underlying acid gastro-oesophageal reflux in normal subjects. However, the presence of oesophageal gas has not been measured directly but only inferred from manometry. 
Aims—To investigate, using intraluminal electrical impedance, the patterns of gas and liquid reflux during transient lower oesophageal sphincter (LOS) relaxations, the main mechanism of acid reflux in normal subjects. 
Methods—Impedance changes ass...

  5. Combined esophageal intraluminal impedance, pH and skin conductance monitoring to detect discomfort in GERD infants.

    Directory of Open Access Journals (Sweden)

    Francesco Cresi

    Full Text Available BACKGROUND: The clinical significance of weakly acidic reflux in infants is unclear. Skin conductance is a novel not-invasive method to evaluate discomfort. The aim of our study was to evaluate reflux-induced discomfort in infants with gastroesophageal reflux disease using simultaneously combined skin conductance and esophageal multichannel intraluminal impedance and pH monitoring. METHODOLOGY/PRINCIPAL FINDINGS: Infants with gastroesophageal reflux symptoms were investigated for almost 20 hours divided into 120-second intervals. Temporal relationships between refluxes and discomfort were evaluated calculating the symptom association probability. Twelve infants aged 17-45 days were studied. Out of 194.38 hours of adequate artifact-free MII/pH and skin conductance monitoring, 584 reflux events were observed; 35.78% were positive for stress, of which 16.27% were acid and 83.73% weakly acidic. A significant association between refluxes and discomfort (p<0.05 was present in all infants. The intervals with reflux events showed increased skin conductance values compared to reflux-free intervals (p<0.001; SC values were similar for acid and weakly acidic reflux events. CONCLUSION/SIGNFICANCE: Discomfort was significantly associated with reflux events and did not differ between weakly acidic and acid refluxes. Our results may raise concerns about the over-prescription use of antacid drugs in the management of gastroesophageal reflux symptoms in infancy.

  6. Blocky inversion of multichannel elastic impedance for elastic parameters

    Science.gov (United States)

    Mozayan, Davoud Karami; Gholami, Ali; Siahkoohi, Hamid Reza

    2018-04-01

    Petrophysical description of reservoirs requires proper knowledge of elastic parameters like P- and S-wave velocities (Vp and Vs) and density (ρ), which can be retrieved from pre-stack seismic data using the concept of elastic impedance (EI). We propose an inversion algorithm which recovers elastic parameters from pre-stack seismic data in two sequential steps. In the first step, using the multichannel blind seismic inversion method (exploited recently for recovering acoustic impedance from post-stack seismic data), high-resolution blocky EI models are obtained directly from partial angle-stacks. Using an efficient total-variation (TV) regularization, each angle-stack is inverted independently in a multichannel form without prior knowledge of the corresponding wavelet. The second step involves inversion of the resulting EI models for elastic parameters. Mathematically, under some assumptions, the EI's are linearly described by the elastic parameters in the logarithm domain. Thus a linear weighted least squares inversion is employed to perform this step. Accuracy of the concept of elastic impedance in predicting reflection coefficients at low and high angles of incidence is compared with that of exact Zoeppritz elastic impedance and the role of low frequency content in the problem is discussed. The performance of the proposed inversion method is tested using synthetic 2D data sets obtained from the Marmousi model and also 2D field data sets. The results confirm the efficiency and accuracy of the proposed method for inversion of pre-stack seismic data.

  7. Correlation of Gastroesophageal reflux disease Assessment Symptom Questionnaire to impedance-pH measurements in children

    OpenAIRE

    Prachuapthunyachart, Sittichoke; Jarasvaraparn, Chaowapong; Gremse, David A

    2017-01-01

    Background: Esophageal multichannel intraluminal impedance-pH monitoring has become one of the preferred tests to correlate observed reflux-like behaviors with esophageal reflux events. The Gastroesophageal reflux disease Assessment Symptom Questionnaire is a validated tool used to distinguish infants with gastroesophageal reflux disease from healthy children. The aim of this study was to determine whether the Gastroesophageal reflux disease Assessment Symptom Questionnaire composite symptom ...

  8. Ambulatory 24-hour multichannel intraluminal impedance-pH monitoring and high resolution endoscopy distinguish patients with non-erosive reflux disease from those with functional heartburn.

    Directory of Open Access Journals (Sweden)

    Chuanlian Chu

    Full Text Available To assess the contribution of 24-h esophageal multichannel intraluminal impedance and pH (MII-pH monitoring and high resolution endoscopy (HRE with i-scan imaging in differentiating non erosive reflux disease (NERD from functional heartburn (FH.This is a retrospective cohort study of patients with heartburn from the Endoscopy Unit. NERD patients and FH patients were defined by 24-h MII-pH monitoring and white light endoscopy. Minimal mucosal changes were assessed by HRE with i-scan imaging.Total of 156 consecutive patients with heartburn but without esophageal mucosal erosions were studied. Forty-eight of these subjects had NERD, with increased acid exposure time (AET and positive SAP and/or SI. Eighteen had FH with normal AET and negative SAP and SI. When compared to FH patients and healthy controls, NERD patients had significantly increased number of total acid reflux episodes, as well as increased number of weakly acidic reflux episodes (p<0.01. The rate of proximal reflux episodes in NERD patients was higher than that of FH patients and healthy controls (p<0.01. Irregular or blurring of the Z-line (58.3% and white mucosal turbidity (47.9% were the most common endoscopic findings of minimal mucosal changes observed in this study. NERD patients had more prevalent minimal changes than FH patients and the controls (87.5%vs. 66.6%vs. 61.9%; p = 0.004 with sensitivity of 87.5%. Histopathological evaluation showed that NERD patients had significantly higher average scores of intercellular spaces dilation (2.82±0.9 vs. 1.2±0.6, p = 0.005 and papillae elongation (2.65±1.0 vs. 1.5±0.8, p = 0.014, but not for basal cell proliferation (1.6±1.3 vs. 1.0±0.9, p = 0.070. The histological scores of the NERD patients were 7.1±1.2, which were higher than those of FH patients (3.4±1.0, p = 0.004.Minimal mucosal changes could be useful markers to support clinical diagnosis of NERD. Combination of 24-h MII-pH monitoring and i-scan high resolution

  9. Ambulatory 24-hour multichannel intraluminal impedance-pH monitoring and high resolution endoscopy distinguish patients with non-erosive reflux disease from those with functional heartburn.

    Science.gov (United States)

    Chu, Chuanlian; Du, Quanlin; Li, Changqing; Zhang, Linlu; Zhou, Xiaoyan; Zuo, Fang; Zhang, Yanmin; Li, Fang; Xie, Guofeng; Li, Yanqing

    2017-01-01

    To assess the contribution of 24-h esophageal multichannel intraluminal impedance and pH (MII-pH) monitoring and high resolution endoscopy (HRE) with i-scan imaging in differentiating non erosive reflux disease (NERD) from functional heartburn (FH). This is a retrospective cohort study of patients with heartburn from the Endoscopy Unit. NERD patients and FH patients were defined by 24-h MII-pH monitoring and white light endoscopy. Minimal mucosal changes were assessed by HRE with i-scan imaging. Total of 156 consecutive patients with heartburn but without esophageal mucosal erosions were studied. Forty-eight of these subjects had NERD, with increased acid exposure time (AET) and positive SAP and/or SI. Eighteen had FH with normal AET and negative SAP and SI. When compared to FH patients and healthy controls, NERD patients had significantly increased number of total acid reflux episodes, as well as increased number of weakly acidic reflux episodes (p<0.01). The rate of proximal reflux episodes in NERD patients was higher than that of FH patients and healthy controls (p<0.01). Irregular or blurring of the Z-line (58.3%) and white mucosal turbidity (47.9%) were the most common endoscopic findings of minimal mucosal changes observed in this study. NERD patients had more prevalent minimal changes than FH patients and the controls (87.5%vs. 66.6%vs. 61.9%; p = 0.004) with sensitivity of 87.5%. Histopathological evaluation showed that NERD patients had significantly higher average scores of intercellular spaces dilation (2.82±0.9 vs. 1.2±0.6, p = 0.005) and papillae elongation (2.65±1.0 vs. 1.5±0.8, p = 0.014), but not for basal cell proliferation (1.6±1.3 vs. 1.0±0.9, p = 0.070). The histological scores of the NERD patients were 7.1±1.2, which were higher than those of FH patients (3.4±1.0, p = 0.004). Minimal mucosal changes could be useful markers to support clinical diagnosis of NERD. Combination of 24-h MII-pH monitoring and i-scan high resolution endoscopy

  10. A multichannel frequency response analyser for impedance spectroscopy on power sources

    Directory of Open Access Journals (Sweden)

    DANIEL J. L. BRETT

    2013-06-01

    Full Text Available A low-cost multi-channel frequency response analyser (FRA has been developed based on a DAQ (data acquisition/LabVIEW interface. The system has been tested for electric and electrochemical impedance measurements. This novel association of hardware and software demonstrated performance comparable to a commercial potentiostat / FRA for passive electric circuits. The software has multichannel capabilities with minimal phase shift for 5 channels when operated below 3 kHz. When applied in active (galvanostatic mode in conjunction with a commercial electronic load (by discharging a lead acid battery at 1.5 A the performance was fit for purpose, providing electrochemical information to characterize the performance of the power source.

  11. Diagnosis and Anti-Reflux Therapy for GERD with Respiratory Symptoms: A Study Using Multichannel Intraluminal Impedance-pH Monitoring

    Science.gov (United States)

    Zhang, Chao; Wu, Jimin; Hu, Zhiwei; Yan, Chao; Gao, Xiang; Liang, Weitao; Liu, Diangang; Li, Fei; Wang, Zhonggao

    2016-01-01

    Background/Aims Respiratory symptoms are often associated with gastroesophageal reflux disease (GERD). Although the role of multichannel intraluminal impedance–pH (MII-pH) monitoring in GERD is clear, little is known regarding the characteristics of patients with respiratory symptoms based on MII-pH monitoring and anti-reflux therapy. We evaluated a cohort of GERD patients to identify the MII-pH parameters of GERD-related respiratory symptoms and to assess the anti-reflux therapy outcomes. Methods We undertook a prospective study of patients who were referred for GERD evaluation from January 2011 to January 2012. One hundred ninety-five patients underwent MII-pH monitoring and esophageal manometry, and one hundred sixty-five patients underwent invasive anti-reflux therapy that included laparoscopic Toupet fundoplication (LTF) and the Stretta procedure. The patient characteristics and MII-pH parameters were analyzed, and the symptom scores were assessed at baseline and at 1- and 3-year follow-up evaluations. Results Of the 195 patients, 96 (49.2%) exhibited respiratory symptoms and significantly more reflux episodes (70.7±29.3) than patients without respiratory symptoms (64.7±24.4, p = 0.044) based on the MII-pH monitoring results. Moreover, the group of patients with respiratory symptoms exhibited more proximal reflux episodes (35.2±21.3) than the non-respiratory symptomatic group (28.3±17.9, p = 0.013). One hundred twenty-five patients following the Stretta procedure (n = 60, 31 with respiratory symptoms) or LTF (n = 65, 35 with respiratory symptoms) completed the designated 3-year follow-up period and were included in the final analysis. The symptom scores after anti-reflux therapy all decreased relative to the corresponding baseline values (p0.05). However, LTF significantly reduced the recurrence (re-operation) rate compared with the Stretta procedure (0 vs. 19.4%, p = 0.006). Conclusions MII-pH monitoring effectively detected respiratory

  12. Combined multichannel intraluminal impedance and pH monitoring is helpful in managing children with suspected gastro-oesophageal reflux disease.

    Science.gov (United States)

    Rossi, Paolo; Isoldi, Sara; Mallardo, Saverio; Papoff, Paola; Rossetti, Danilo; Dilillo, Anna; Oliva, Salvatore

    2018-04-05

    Gastro-oesophageal reflux is very common in the paediatric age group. There is no single and reliable test to distinguish between physiologic and pathological gastro-oesophageal reflux, and this lack of clear distinction between disease and normal can have a negative impact on the management of children. To evaluate the usefulness of 24-h oesophageal pH-impedance study in infants and children with suspected gastro-oesophageal reflux disease. Patients were classified by age groups (A-C) and reflux-related symptoms (typical and atypical). All underwent pH-impedance study. If the latter suggested an abnormal reflux, patients received therapy in accordance with NASPGHAN/ESPGHAN recommendations, while those with normal study had an additional diagnostic work-up. The efficacy of therapy was evaluated with a specific standardized questionnaire for different ages. The study was abnormal in 203/428 patients (47%) while normal in 225/428 (53%). Of those with abnormal study, 109 exhibited typical symptoms (54%), and 94 atypical (46%). The great majority of the patients with abnormal study were responsive to medical anti-reflux therapy. We confirm the utility of prolonged oesophageal pH-impedance study in detecting gastro-oesophageal reflux disease in children and in guiding therapy. Performing oesophageal pH-impedance monitoring in children with suspected gastro-oesophageal reflux disease is helpful to establish the diagnosis and avoid unnecessary therapy. Copyright © 2018 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

  13. Novas técnicas ambulatoriais para avaliação da motilidade esofágica e sua aplicação no estudo do megaesôfago

    Directory of Open Access Journals (Sweden)

    Fernando A. M. Herbella

    Full Text Available Brazilian surgeons deal routinely with esophageal motility disorders, because achalasia is highly prevalent in Brazil due to Chagas' disease. In the last years new technologies for the evaluation of esophageal motility became available. High resolution manometry and the combination of barometric parameters and intraluminal impedance are the new frontiers on this topic. The authors reviewed current, national and international, literature about achalasia with multichannel intraluminal impedance and high resolution manometry studies. The new technologies described are promising, however few studies have been published and further studies are still expected for achalasia patients.

  14. Transcutaneous Intraluminal Impedance Measurement for Minimally Invasive Monitoring of Gastric Motility: Validation in Acute Canine Models

    Directory of Open Access Journals (Sweden)

    Michael D. Poscente

    2014-01-01

    Full Text Available Transcutaneous intraluminal impedance measurement (TIIM is a new method to cutaneously measure gastric contractions by assessing the attenuation dynamics of a small oscillating voltage emitted by a battery-powered ingestible capsule retained in the stomach. In the present study, we investigated whether TIIM can reliably assess gastric motility in acute canine models. Methods. Eight mongrel dogs were randomly divided into 2 groups: half received an active TIIM pill and half received an identically sized sham capsule. After 24-hour fasting and transoral administration of the pill (active or sham, two force transducers (FT were sutured onto the antral serosa at laparotomy. After closure, three standard cutaneous electrodes were placed on the abdomen, registering the transluminally emitted voltage. Thirty-minute baseline recordings were followed by pharmacological induction of gastric contractions using neostigmine IV and another 30-minute recording. Normalized one-minute baseline and post-neostigmine gastric motility indices (GMIs were calculated and Pearson correlation coefficients (PCCs between cutaneous and FT GMIs were obtained. Statistically significant GMI PCCs were seen in both baseline and post-neostigmine states. There were no significant GMI PCCs in the sham capsule test. Further chronic animal studies of this novel long-term gastric motility measurement technique are needed before testing it on humans.

  15. Intraesophageal impedance monitoring: clinical studies

    NARCIS (Netherlands)

    Conchillo Armendáriz, J.M.

    2007-01-01

    Electrical impedance (Z) between two electrodes is the ratio between applied voltage (U) and resulting current (I). In electrical impedance monitoring the resistance to electrical flow in an alternating current circuit is measured. Multichannel esophageal monitoring can be measured by using an

  16. Correlation between hypersensitivity induced by esophageal acid infusion and the baseline impedance level in patients with suspected gastroesophageal reflux.

    Science.gov (United States)

    Seo, A Young; Shin, Cheol Min; Kim, Nayoung; Yoon, Hyuk; Park, Young Soo; Lee, Dong Ho

    2015-07-01

    To evaluate the relevance between the pH parameters and baseline impedance level or esophageal hypomotility in patients with suspected gastroesophageal reflux. The recordings of 51 patients with heartburn, acid regurgitation, globus or noncardiac chest pain were analyzed. Evaluation included a 24-h multichannel intraluminal impedance-pH test while on off-proton pump inhibitor therapy over 1 week, high-resolution manometry and Bernstein test. Mean baseline impedance level at the most distal portion of the impedance channel was assessed manually. Esophageal hypomotility was evaluated using transitional zone defect (TZD) and distal break (DB) length measurement. In the study subjects (n = 51), 6 had a DeMeester score of more than 14.7 and 14 had a positive symptom index. The Bernstein test was positive in ten patients. The baseline impedance level was inversely correlated with the acid exposure time % (r = -0.660, P reflux and weakly acid reflux time % measured by impedance monitoring showed a weak correlation with TZD + DB length (r = 0.327 and 0.324, P = 0.019 and 0.020, respectively). Although a positive Bernstein test has no relevance for the acid exposure time or acid-related symptoms as represented by the DeMeester score or symptom index, the baseline impedance level was significantly lower in patients with a positive Bernstein test than in those with a negative one (2,628.4 ± 862.7 vs. 1,752.2 ± 611.1 Ω, P = 0.004). A lower baseline impedance level is closely related to increased esophageal acid exposure. Hypersensitivity induced by esophageal acid infusion might be attributed to acid-induced mucosal changes of the esophagus.

  17. Oesophageal baseline impedance values are decreased in patients with eosinophilic oesophagitis

    NARCIS (Netherlands)

    van Rhijn, Bram D.; Kessing, Boudewijn F.; Smout, Andreas J. P. M.; Bredenoord, Albert J.

    2013-01-01

    Background: Gastro-oesophageal reflux has been suggested to play a role in eosinophilic oesophagitis (EoO). Oesophageal acid exposure decreases baseline intraluminal impedance, a marker of mucosal integrity, in patients with gastro-oesophageal reflux disease (GORD). Objectives: The aim of this study

  18. Appendicitis with Intraluminal Air

    International Nuclear Information System (INIS)

    Fernandez, Alfredo; Ramirez, Sandra M; Rodriguez, Cesar A; Uriza, Luis F

    2010-01-01

    The presentation of acute appendicitis with intraluminal air is an uncommon presentation. Ultrasound is a widely used and accepted to establish the diagnosis of appendicitis, but its performance is limited in situations where there is interposition of air. Inflamed appendix which presents with distension by gas can be source of error in ultrasound to establish a false negative diagnosis. In this article we present three patients with appendicitis where the interposition of intraluminal air hid their diagnostic by ultrasound. In all three cases the definitive diagnosis was established by computed tomography and surgical confirmation.

  19. 24 h多通道腔内阻抗联合pH监测诊断咽喉反流的初步应用%Application of 24-hour multichannel intraluminal impedance in combination with pH monitoring for the diagnosis of laryngopharyngeal reflux: a pilot study

    Institute of Scientific and Technical Information of China (English)

    王嘉森; 李进让; 李晓雨; 马宁

    2015-01-01

    Objective To explore the diagnostic characteristics of 24 hours multichannel intraluminal impedance-pH (MII-pH) monitoring in patients with laryngopharyngeal reflux (LPR).Methods Patients who were suspected to have laryngopharyngeal reflux (LRP) between February and December 2014 were included.The frequency of pH < 4 waveform,artifacts,numbers of acid reflux events,weakly acidic reflux events,weakly alkaline reflux events,time of acid exposure,time of acid clearance,acid reflux events in upright position and supine position,reflux symptom index (RSI) and reflux findings score (RFS) were analyzed.Results Forty-five times pH < 4 reflux waveform were identified according to software analysis.140 pH drops of 4 were observed according to manual analysis,in which 78 times were caused by reflux and 62 artifacts.The consistency of manual analysis and software automatically analysis was general (κ =0.234).The positive rate of 60 patients was 28.3% (17/60).In the 17 LPR patients,the median number[P25,P75] of acid reflux events was 5.0[4.0,8.8],weakly acidic reflux events was 6.5 [5.3,10.3],weakly alkaline reflux events was 1.0 [0.0,2.0],time of acid exposure was 3.8 [2.3,7.2] min,time of acid clearance was 36.0 [21.5,57.6] s,acid reflux events in upright position was 4.0[3.0,4.8] and in supine position was 1.5 [0.0,2.3].All the data were approximately identical with the domestic and foreign literature.24 hours MII-pH monitoring and RSI + RFS had medium consistency (κ =0.590).Conclusions 24 hours MII-pH monitoring has ideal repeatability,but false positive and false negative can not be avoided completely.The diagnosis of laryngopharyngeal reflux shoull be combined with medical history and laryngoscopy.%目的 研究24 h多通道腔内阻抗联合pH监测(multichannel intraluminal impedance,MII-pH)在诊断咽喉反流中的特点和问题.方法 对2014年2-12月怀疑存在咽喉反流的60例患者行24 h MII-pH监测,统计pH<4

  20. Reflux episodes and esophageal impedance levels in patients with typical and atypical symptoms of gastroesophageal reflux disease

    Science.gov (United States)

    Ye, Bi Xing; Jiang, Liu Qin; Lin, Lin; Wang, Ying; Wang, Meifeng

    2017-01-01

    Abstract To determine the relationship between baseline impedance levels and gastroesophageal reflux, we retrospectively enrolled 110 patients (54 men and 56 female; mean age, 51 ± 14 years) with suspected gastroesophageal reflux disease (GERD) who underwent 24-h multichannel intraluminal impedance and pH monitoring. Patients were stratified according to symptom (typical or atypical) and reflux types (acid reflux, nonacid reflux [NAR], or no abnormal reflux). Mean nocturnal baseline impedance (MNBI) were measured 3 cm (distal esophagus) and 17 cm (proximal esophagus) above the lower esophageal sphincter. Median distal esophageal MNBI was lower in the acid reflux group (1244 Ω; 647–1969 Ω) than in the NAR (2586 Ω; 1368–3666 Ω) or no abnormal reflux groups (3082 Ω; 2495–4472 Ω; all P < .05). Distal MNBI were negatively correlated with DeMeester score and acid exposure time. Atypical symptoms were more frequently associated with NAR than typical symptoms (P < .01). Among patients with positive symptom-association probability (SAP) for NAR, median proximal MNBI tended to be lower in patients with typical symptoms (median, 3013 Ω; IQR, 2535–3410 Ω) than in those with atypical symptoms (median, 3386 Ω; IQR, 3044–3730 Ω, P = .05). Thus, atypical GERD symptoms were more likely to be associated with NAR. The mucosal integrity of the proximal esophagus might be relatively impaired in GERD patients with typical symptoms for NAR. PMID:28906377

  1. Wireless Impedance-Based SHM for Bolted Connections via Multiple PZT-Interfaces

    International Nuclear Information System (INIS)

    Nguyen, Khac Duy; Kim, Jeong Tae

    2011-01-01

    This study presents a structural health monitoring(SHM) method for bolted connections by using multi-channel wireless impedance sensor nodes and multiple PZT-interfaces. To achieve the objective, the following approaches are implemented. Firstly, a PZT-interface is designed to monitor bolt loosening in bolted connection based on variation of electro-mechanical(EM) impedance signatures. Secondly, a wireless impedance sensor node is designed for autonomous, cost-efficient and multi-channel monitoring. For the sensor platform, Imote2 is selected on the basis of its high operating speed, low power requirement and large storage memory. Finally, the performance of the wireless sensor node and the PZT-interfaces is experimentally evaluated for a bolt-connection model. Damage monitoring method using root mean square deviation(RMSD) index of EM impedance signatures is utilized to estimate the strength of the bolted joint

  2. Assessment of bolus transit with intraluminal impedance measurement in patients with esophageal motility disorders.

    Science.gov (United States)

    Bogte, A; Bredenoord, A J; Oors, J; Siersema, P D; Smout, A J P M

    2015-10-01

    The clinical management of patients with non-obstructive dysphagia is notoriously difficult. Esophageal impedance measurement can be used to measure esophageal bolus transit without the use of radiation exposure to patients. However, validation of measurement of bolus transit with impedance monitoring has only been performed in healthy subjects with normal motility and not in patients with dysphagia and esophageal motility disorders. The aim was, therefore, to investigate the relationship between transit of swallowed liquid boluses in healthy controls and in patients with dysphagia. Twenty healthy volunteers and 20 patients with dysphagia underwent concurrent impedance measurement and videofluoroscopy. Each subject swallowed five liquid barium boluses. The ability of detecting complete or incomplete bolus transit by means of impedance measurement was assessed, using radiographic bolus transit as the gold standard. Impedance monitoring recognized stasis and transit in 80.5% of the events correctly, with 83.9% of bolus transit being recognized and 77.2% of stasis being recognized correctly. In controls 79.8% of all swallows were scored correctly, whereas in patients 81.3% of all swallows were scored correctly. Depending on the contractility pattern, between 77.0% and 94.3% of the swallows were scored correctly. Impedance measurement can be used to assess bolus clearance patterns in healthy subjects, but can also be used to reliably assess bolus transit in patients with dysphagia and motility disorders. © 2015 John Wiley & Sons Ltd.

  3. Indications of 24-h esophageal pH monitoring, capsule pH monitoring, combined pH monitoring with multichannel impedance, esophageal manometry, radiology and scintigraphy in gastroesophageal reflux disease?

    Science.gov (United States)

    Vardar, Rukiye; Keskin, Muharrem

    2017-12-01

    Ambulatory esophageal pH monitoring is an essential method in patients exhibiting signs of non-erosive reflux disease (NERD) to make an objective diagnosis. Intra-esophageal pH monitoring is important in patients who are non-responsive to medications and in those with extraesophageal symptoms, particularly in NERD, before surgical interventions. With the help of the wireless capsule pH monitoring, measurements can be made under more physiological conditions as well as longer recordings can be performed because the investigation can be better tolerated by patients. Ambulatory esophageal pH monitoring can be detected within normal limits in 17%-31.4% of the patients with endoscopic esophagitis; therefore, normal pH monitoring cannot exclude the diagnosis of gastroesophageal reflux disease (GERD). Multi-channel intraluminal impedance pH (MII-pH) technology have been developed and currently the most sensitive tool to evaluate patients with both typical and atypical reflux symptoms. The sensitivity of a pH catheter test is 58% for the detection of acid reflux compared with MII-pH monitoring; further, its sensitivity is 28% for the detection of weak acid reflux compared with MII-pH monitoring. By adding impedance to pH catheter in patients with reflux symptoms, particularly in those receiving PPIs, it has been demonstrated that higher rates of diagnoses and symptom analyses can be obtained than those using only pH catheter. Esophageal manometry is used in the evaluation of patients with functional dysphagia and unexplained noncardiac chest pain and prior to antireflux surgery. The use of esophageal manometry is suitable for the detection of esophageal motor patterns and extreme motor abnormalities (e.g., achalasia and extreme hypomotility). Esophageal manometry and ambulatory pH monitoring are often used in assessments prior to laparoscopic antireflux surgery and in patients with reflux symptoms refractory to medical treatment. Although the esophageal motility is

  4. The role of baseline impedance as a marker of mucosal integrity in children with gastro esophageal reflux disease.

    Science.gov (United States)

    Pilic, Denisa; Hankel, Saskia; Koerner-Rettberg, Cordula; Hamelmann, Eckard; Schmidt-Choudhury, Anjona

    2013-07-01

    Diagnosis of gastro esophageal reflux disease (GERD) in children is challenging. 24-h-pH-multichannel-intraluminal-impedance measurement (pH-MII) is the best diagnostic tool to display gastro esophageal reflux whereas esophageal endoscopy indicates mucosal lesions. The aim of this study was to compare esophageal endoscopy results with reflux parameters such as acid exposure time (reflux index RI), bolus exposure time (bolus index BI), baseline impedance level (BIL) detected by pH-MII in children with suspected GERD. Analysis of data from 285 children (38 infants) referred to our hospital with suspected GERD. Division into three 'reflux esophagitis' (RE)-stages depending on the severity of endoscopic and histological findings and comparison with reflux parameters in these stages. Further categorization into four groups based on the pH-MII-results. Children with high-grade esophagitis had a significantly lower BIL; otherwise there was no significant association between elevated reflux parameters and esophagitis. Pathological pH-MII results (RI and BI) were associated with lower BIL in the distal impedance channel. The BIL was significantly lower in infants compared to children >1 year regardless of the RI or BI. The main difference between these groups regarding reflux parameters was a longer BI and a higher number of retrograde bolus movements. Pathologic pH-MII results are not predictive for an erosive esophagitis and vice versa. Therefore, these two procedures cannot replace each other. A lower BIL is associated with esophagitis ≥ LA-grade B and may be caused by longer acid but also by longer bolus exposure and thus may be another useful parameter in GERD monitoring.

  5. Gastro-oesophageal reflux is common in oligosymptomatic patients with dental erosion: A pH-impedance and endoscopic study.

    Science.gov (United States)

    Wilder-Smith, Clive H; Materna, Andrea; Martig, Lukas; Lussi, Adrian

    2015-04-01

    Dental erosion is a complication of gastro-oesophageal reflux disease (GORD) according to the Montreal consensus statement. However, GORD has not been comprehensively characterized in patients with dental erosions and pH-impedance measures have not been reported. Characterize GORD in patients with dental erosions using 24-h multichannel intraluminal pH-impedance measurements (pH-MII) and endoscopy. This single-centre study investigated reflux in successive patients presenting to dentists with dental erosion using pH-MII and endoscopy. Of the 374 patients, 298 (80%) reported GORD symptoms reflux episodes were 71 (63-79), 43 (38-49) and 31 (26-35), respectively. Of the reflux episodes, 19% (17-21) reached the proximal oesophagus. In 241 (69%) patients reflux was abnormal using published normal values for acid exposure time and reflux episodes. No significant associations between the severity of dental erosions and any reflux variables were found. The presence of GORD symptoms and of oesophagitis or a hiatal hernia was associated with greater reflux, but not with increased dental erosion scores. Significant oligosymptomatic gastro-oesophageal reflux occurs in the majority of patients with dental erosion. The degree of dental erosion did not correlate with any of the accepted quantitative reflux indicators. Definition of clinically relevant reflux parameters by pH-MII for dental erosion and of treatment guidelines are outstanding. Gastroenterologists and dentists need to be aware of the widely prevalent association between dental erosion and atypical GORD.

  6. Is the Routine Use of Impedance Analysis for the Diagnosis of Gastro-Esophageal Reflux Disease More Expensive than Conventional pH Monitoring? Cost Analysis of Two Procedures.

    Science.gov (United States)

    Törer, Nurkan; Aytaç, Özgür

    2017-06-01

    Conventional 24-h pH monitoring is the gold standard for the diagnosis of non-erosive, non-acidic gastro-esophageal reflux disease. Multichannel Intraluminal Impedance (MII) analysis markedly improves diagnostic accuracy of non-erosive, non-acidic gastro-esophageal reflux disease. However, MII catheters are more expensive than standard catheters. This study aimed to determine the rates of acid or non-acid reflux and by making a retrospective projection, to predict the costs of two algorithms. We retrospectively reviewed the medical data of 102 patients who presented to our hospital with suspected non-erosive GERD and underwent 24 h impedance/pH-monitoring. Demographic characteristics, Demeester scores, number of reflux episodes, and results of impedance analysis were recorded. According to these data, cost was calculated either for the scenario in which impedance measurement was performed solely or following a negative conventional pH monitoring. Thirty-seven of all 102 patients (36.3 %) had a Demeester score greater than 14.7. These patients were assigned as group 1 (acid reflux). The impedance analysis of the remaining 65 patients detected 34 patients (33.3 %) to have more than 50 reflux episodes over a period of 24 h and assigned as Group 2, and 31 patients (30.4 %) had no reflux (group 3). The cost of the single- step algorithm using MII catheter was calculated as $15,300, while the total cost of two-step scenario would have been predicted as $16,890. Our study showed that an initial conventional pH monitoring can make the diagnosis of GERD in only one third of the patients with suspected non-erosive GERD. In nearly two-thirds of patients, however, repeated procedures and use of impedance catheters are needed. It is clear that this algorithm has certain drawbacks with regard to cost, patient comfort, and workforce loss.

  7. The Relationship of the Post-reflux Swallow-induced Peristaltic Wave Index and Esophageal Baseline Impedance with Gastroesophageal Reflux Disease Symptoms

    Science.gov (United States)

    Cho, Young Kyu; Lee, Joon Seong; Lee, Tae Hee; Hong, Su Jin; Park, Sang Joon; Jeon, Seong Ran; Kim, Hyun Gun; Kim, Jin-Oh

    2017-01-01

    Background/Aims The post-reflux swallow-induced peristaltic wave (PSPW) index and esophageal baseline impedance (BI) are novel impedance parameters used to evaluate esophageal chemical clearance and mucosal integrity. However, their relationship with reflux symptoms is not known. We aim to evaluate the correlations of PSPW index and esophageal BI with gastroesophageal reflux disease (GERD) symptoms. Methods We performed a retrospective review of multichannel intraluminal impedance and pH (MII-pH) tracings in patients with suspected GERD. Reflux symptoms were also analyzed from checklists using ordinal scales. The PSPW index and esophageal BIs in 6 spots (z1–z6) were measured. Bivariate (Spearman) correlation was used to analyze the relationship between the PSPW index or esophageal BI, and the degree of GERD symptoms measured. Results The MII-pH records of 143 patients were analyzed. The PSPW index was significantly lower in patients who had heartburn and negatively correlated with the degree of heartburn (r = −0.186, P < 0.05). On the contrary, the PSPW index was not significantly correlated with the degree of dysphagia (r = −0.013, P = 0.874). Distal esophageal BI was not significantly correlated with heartburn, but negatively correlated with the degree of dysphagia (z3: r = −0.328, z4: r = −0.361, z5: r = −0.316, z6: r = −0.273; P < 0.05). Conclusions These findings suggest that delayed chemical clearance of the esophagus may induce heartburn, but that it is not related to dysphagia. However, a lack of esophageal mucosal integrity may be related to dysphagia. PMID:28044052

  8. Gastro-oesophageal reflux is common in oligosymptomatic patients with dental erosion: A pH-impedance and endoscopic study

    Science.gov (United States)

    Materna, Andrea; Martig, Lukas; Lussi, Adrian

    2015-01-01

    Background Dental erosion is a complication of gastro-oesophageal reflux disease (GORD) according to the Montreal consensus statement. However, GORD has not been comprehensively characterized in patients with dental erosions and pH-impedance measures have not been reported. Objectives Characterize GORD in patients with dental erosions using 24-h multichannel intraluminal pH-impedance measurements (pH-MII) and endoscopy. Methods This single-centre study investigated reflux in successive patients presenting to dentists with dental erosion using pH-MII and endoscopy. Results Of the 374 patients, 298 (80%) reported GORD symptoms reflux episodes were 71 (63–79), 43 (38–49) and 31 (26–35), respectively. Of the reflux episodes, 19% (17–21) reached the proximal oesophagus. In 241 (69%) patients reflux was abnormal using published normal values for acid exposure time and reflux episodes. No significant associations between the severity of dental erosions and any reflux variables were found. The presence of GORD symptoms and of oesophagitis or a hiatal hernia was associated with greater reflux, but not with increased dental erosion scores. Conclusions Significant oligosymptomatic gastro-oesophageal reflux occurs in the majority of patients with dental erosion. The degree of dental erosion did not correlate with any of the accepted quantitative reflux indicators. Definition of clinically relevant reflux parameters by pH-MII for dental erosion and of treatment guidelines are outstanding. Gastroenterologists and dentists need to be aware of the widely prevalent association between dental erosion and atypical GORD. PMID:25922678

  9. [Multi-channel cochlear implants in patients with Mondini malformation].

    Science.gov (United States)

    Li, Yong-xin; Han, De-min; Zhao, Xiao-tian; Chen, Xue-qing; Kong, Ying; Zheng, Jun; Liu, Bo; Liu, Sha; Mo, Ling-yan; Zhang, Hua; Wang, Shuo

    2004-02-01

    To describe clinical experiences with multi-channel cochlear implantation in patients with Mondini malformation. Among 300 patients who received multi-channel cochlear implants from 1996 to 2002 in Beijing Tongren Hospital, 15 patients were diagnosed with Mondini malformation. A retrospective analysis was performed dealing with the surgical techniques, mapping and rehabilitations characteristics after surgery. 15 patients with normal cochlear structure are consider as control group. Gusher is found more common than the normal cochlear implantation, most of them are serious. The electrodes are inserted in the "cochleostomy" in full length of 13 Patients, 2 pairs of electrodes remains outside of "cochleostomy" in 2 patients. No serious complications occurred after implantation. All patients have auditory sensations. The impedance of the electrodes, the T level, C level and the hearing threshold are similar with the normal cochlear implantation group. The results have no significant difference in compare with normal cochlear group(P > 0.05). Multi-channel cochlear implantation could be performed safely in patients with Mondini malformation. The primary outcome for patients with Mondini malformation are similar to those with normal cochlear structure following the multi-channel cochlear implantation.

  10. Concurrent duodenal manometric and impedance recording to evaluate the effects of hyoscine on motility and flow events, glucose absorption, and incretin release

    NARCIS (Netherlands)

    Chaikomin, Reawika; Wu, Keng Liang; Doran, Selena; Jones, Karen L.; Smout, Andre J. P. M.; Renooij, Willem; Holloway, Richard H.; Meyer, James H.; Horowitz, Michael; Rayner, Christopher K.

    2007-01-01

    Upper gastrointestinal motor function and incretin hormone secretion are major determinants of postprandial glycemia and insulinemia. However, the impact of small intestinal flow events on glucose absorption and incretin release is poorly defined. Intraluminal impedance monitoring is a novel

  11. Large Intraluminal Ileal Hematoma Presenting as Small Bowel Obstruction in a Child

    International Nuclear Information System (INIS)

    Lim, Yun Jung; Nam, So Hyun; Kim, Seon Jeong

    2015-01-01

    Intraluminal small bowel hematoma has been rarely reported in children, as a rare cause of small bowel obstruction. We present a case of an intraluminal ileal hematoma presenting as small bowel obstruction in a child. Computed Tomography (CT) indicated a large intraluminal hyperdense lesion in the distal ileum as the cause of small bowel obstruction. Abdominal ultrasonography (US) showed an echogenic mass-like lesion with multiple septa in the distal ileum. Small bowel obstruction due to a complicated cystic mass was provisionally diagnosed. Histopathologic examination of the resected mass suggested a submucosal ileal hematoma. Although intraluminal small bowel hematoma is rare in children, it can present as an intraluminal cystic mass and should be considered as a rare cause of small bowel obstruction. The US and CT findings of submucosal ileal hematoma could be useful for the diagnosis of such cases in the future

  12. Evaluating outcomes of endoscopic full-thickness plication for gastroesophageal reflux disease (GERD) with impedance monitoring.

    Science.gov (United States)

    von Renteln, Daniel; Schmidt, Arthur; Riecken, Bettina; Caca, Karel

    2010-05-01

    Endoscopic full-thickness plication allows transmural suturing at the gastroesophageal junction to recreate the antireflux barrier. Multichannel intraluminal impedance monitoring (MII) can be used to detect nonacid or weakly acidic reflux, acidic swallows, and esophageal clearance time. This study used MII to evaluate the outcome of endoscopic full-thickness plication. In this study, 12 subsequent patients requiring maintenance proton pump inhibitor therapy underwent endoscopic full-thickness plication for treatment of gastroesophageal reflux disease. With patients off medication, MII was performed before and 6-months after endoscopic full-thickness plication. The total median number of reflux episodes was significantly reduced from 105 to 64 (p = 0.016). The median number of acid reflux episodes decreased from 73 to 43 (p = 0.016). Nonacid reflux episodes decreased from 23 to 21 (p = 0.306). The median bolus clearance time was 12 s before treatment and 11 s at 6 months (p = 0.798). The median acid exposure time was reduced from 6.8% to 3.4% (p = 0.008), and the DeMeester scores were reduced from 19 to 12 (p = 0.008). Endoscopic full-thickness plication significantly reduced total reflux episodes, acid reflux episodes, and total reflux exposure time. The DeMeester scores and total acid exposure time for the distal esophagus were significantly improved. No significant changes in nonacid reflux episodes and median bolus clearance time were encountered.

  13. Esophageal mucosal integrity improves after laparoscopic antireflux surgery in children with gastroesophageal reflux disease.

    Science.gov (United States)

    Mauritz, Femke A; Rinsma, Nicolaas F; van Heurn, Ernest L W; Sloots, Cornelius E J; Siersema, Peter D; Houwen, Roderick H J; van der Zee, David C; Masclee, Ad A M; Conchillo, José M; Van Herwaarden-Lindeboom, Maud Y A

    2017-07-01

    Esophageal intraluminal baseline impedance reflects the conductivity of the esophageal mucosa and may be an instrument for in vivo evaluation of mucosal integrity in children with gastroesophageal reflux disease (GERD). Laparoscopic antireflux surgery (LARS) is a well-established treatment option for children with proton pump inhibitory (PPI) therapy resistant GERD. The effect of LARS in children on baseline impedance has not been studied in detail. The aim of this study was to evaluate the effect of LARS on baseline impedance in children with GERD. This is a prospective, multicenter, nationwide cohort study (Dutch national trial registry: NTR2934) including 25 patients [12 males, median age 6 (range 2-18) years] with PPI-resistant GERD scheduled to undergo LARS. Twenty-four hour multichannel intraluminal impedance pH monitoring (MII-pH monitoring) was performed before and 3 months after LARS. Baseline impedance was evaluated during consecutive 2-h intervals in the 24-h tracings. LARS reduced acid exposure time from 8.5 % (6.0-16.2 %) to 0.8 % (0.2-2.8 %), p < 0.001. Distal baseline impedance increased after LARS from 2445 Ω (1147-3277 Ω) to 3792 Ω (3087-4700 Ω), p < 0.001. Preoperative baseline impedance strongly correlated with acid exposure time (r -0.76, p < 0.001); however, no association between symptomatic outcome and baseline impedance was identified. LARS significantly increased baseline impedance likely reflecting recovery of mucosal integrity. As the change in baseline impedance was not associated with the clinical outcome of LARS, other factors besides mucosal integrity may contribute to symptom perception in children with GERD.

  14. Multichannel simultaneous magnetic induction measurement system (MUSIMITOS)

    International Nuclear Information System (INIS)

    Steffen, Matthias; Leonhardt, Steffen; Heimann, Konrad; Bernstein, Nina

    2008-01-01

    Non-contact heart and lung activity monitoring would be a desirable supplement to conventional monitoring techniques. Based on the potential of non-contact magnetic induction measurements, requirements for an adequate monitoring system were estimated. This formed the basis for the development of the presented extendable multichannel simultaneous magnetic induction measurement system (MUSIMITOS). Special focus was given to the dynamic behaviour and simultaneous multichannel measurements, so that the system allows for up to 14 receiver coils working simultaneously at 6 excitation frequencies. Moreover, a real-time software concept for online signal processing visualization in combination with a fast software demodulation is presented. Finally, first steps towards a clinical application are pointed out and technical performance as well as first in vivo measurements are presented. This paper covers some aspects previously presented in Steffen and Leonhardt (2007 Proc. 13th Int. Conf. on Electrical Bioimpedance and the 8th Conf. on Electrical Impedance Tomography, Graz 2007)

  15. Intraluminal milrinone for dilation of the radial artery graft.

    Science.gov (United States)

    García-Rinaldi, R; Soltero, E R; Carballido, J; Mojica, J

    1999-01-01

    There is renewed interest in the use of the radial artery as a conduit for coronary artery bypass surgery. The radial artery is, however, a very muscular artery, prone to vasospasm. Milrinone, a potent vasodilator, has demonstrated vasodilatory properties superior to those of papaverine. In this report, we describe our technique of radial artery harvesting and the adjunctive use of intraluminal milrinone as a vasodilator in the preparation of this conduit for coronary artery bypass grafting. We have used these techniques in 25 patients who have undergone coronary artery bypass grafting using the radial artery. No hand ischemic complications have been observed in this group. Intraluminal milrinone appears to dilate and relax the radial artery, rendering this large conduit spasm free and very easy to use. We recommend the skeletonization technique for radial artery harvesting and the use of intraluminal milrinone as a radial artery vasodilator in routine myocardial revascularization. PMID:10524740

  16. Impedance Changes Indicate Proximal Ventriculoperitoneal Shunt Obstruction In Vitro.

    Science.gov (United States)

    Basati, Sukhraaj; Tangen, Kevin; Hsu, Ying; Lin, Hanna; Frim, David; Linninger, Andreas

    2015-12-01

    Extracranial cerebrospinal fluid (CSF) shunt obstruction is one of the most important problems in hydrocephalus patient management. Despite ongoing research into better shunt design, robust and reliable detection of shunt malfunction remains elusive. The authors present a novel method of correlating degree of tissue ingrowth into ventricular CSF drainage catheters with internal electrical impedance. The impedance based sensor is able to continuously monitor shunt patency using intraluminal electrodes. Prototype obstruction sensors were fabricated for in-vitro analysis of cellular ingrowth into a shunt under static and dynamic flow conditions. Primary astrocyte cell lines and C6 glioma cells were allowed to proliferate up to 7 days within a shunt catheter and the impedance waveform was observed. During cell ingrowth a significant change in the peak-to-peak voltage signal as well as the root-mean-square voltage level was observed, allowing the impedance sensor to potentially anticipate shunt malfunction long before it affects fluid drainage. Finite element modeling was employed to demonstrate that the electrical signal used to monitor tissue ingrowth is contained inside the catheter lumen and does not endanger tissue surrounding the shunt. These results may herald the development of "next generation" shunt technology that allows prediction of malfunction before it affects patient outcome.

  17. Identification of intraluminal thrombus by ultrasonography in emergency department patients with acute deep venous thrombosis.

    Science.gov (United States)

    Mehta, Ninfa; Schecter, Joshua; Stone, Michael

    2012-05-01

    Traditionally, the diagnosis of deep venous thrombosis (DVT) using duplex ultrasonography (DU) has relied on the absence of venous compressibility. Visualization of an intraluminal thrombus is considered an uncommon finding. The purpose of this study is to determine the frequency of intraluminal thrombus in emergency department (ED) patients diagnosed with acute DVT. Retrospective chart review of adult ED patients with DU examinations demonstrating acute DVT. Patients with chronic DVT or patients in whom DU did not demonstrate DVT were excluded from data analysis. Study reports and ultrasound images were reviewed and analyzed for the presence of intraluminal thrombus. There were 189 patients who met inclusion criteria, of which 160 (85%) were found to have intraluminal thrombus. Intraluminal thrombi are present in the majority of patients in our ED in whom acute DVT is identified by DU. Copyright © 2012 Elsevier Inc. All rights reserved.

  18. Preoperative intraluminal irradiation of the extrahepatic bile duct tumor

    International Nuclear Information System (INIS)

    Kamada, Tadashi; Tsujii, Hirohiko; Arimoto, Takuro; Irie, Goro.

    1991-01-01

    From 1984 through 1986, six patients with extrahepatic bile duct tumor were treated preoperatively with intraluminal irradiation of the bile duct. There were no unresectable cases and pathological examination of the surgical specimens showed moderate to remarkable tumor regression in all cases. Postoperative biliary tract hemorrhage occurred in 2 of 3 patients who received 60 Gy at a point 7.5 mm from the center of the source. With accurate preoperative diagnosis of the tumor extent and careful setting of the target area of intraluminal irradiation, improved local tumor control of extrahepatic bile duct tumor can be expected with this method. (author)

  19. Intra-luminal brachytherapy of bile duct tumors

    International Nuclear Information System (INIS)

    Udaya Kumar Maiya, M.; Bhat, Naresh; Praveen, L.S.

    2000-01-01

    The objective of this study has been to assess the feasibility of intraluminal brachytherapy of the biliary ductal system. The technique of the procedure with its attendant problems and how to overcome the same will be discussed in detail

  20. Detection of gastro-oesophageal reflux in the neonatal unit.

    Science.gov (United States)

    Rossor, Thomas; Lingam, Ingran; Douiri, Abdel; Bhat, Ravindra; Greenough, Anne

    2018-03-13

    To determine whether a pH probe or multichannel intraluminal impedance (MII) more frequently detected gastro-oesophageal reflux and test the hypothesis that acid reflux was associated with lower baseline impedance. A prospective study of infants in whom reflux was suspected and evaluated using combined pH and multichannel impedance. Studies were considered abnormal if the acid index was >10% or there were >79MII reflux events in 24 hours. The acid index was the percentage of total study time with a pHacid clearance time (ACT) the time from the pH falling below four to rising above four. Forty-two infants [median gestational age 31 (range 23-42) weeks] were assessed. Only nine infants (21%) had abnormal studies, seven detected by pH monitoring, one by MII monitoring and one by both techniques (p = 0.04). After correcting for gestational age and post-natal age, baseline impedance remained negatively correlated with the acid index (r = -0.34, p = 0.038) and the maximum ACT (r = -0.44, p = 0.006). Clinical suspicion of reflux was frequently incorrect, and reflux was more frequently detected by a pH probe. The inverse relationship of acid reflux to baseline impedance suggests that mucosal disruption may result from acid reflux in this population. ©2018 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  1. Magnetic Retraction of Bowel by Intraluminal Injectable Cyanoacrylate-Based Magnetic Glue

    Directory of Open Access Journals (Sweden)

    Zhigang Wang

    2013-01-01

    Full Text Available Magnetic retraction offers advantages over physical retraction by graspers because of reduced tissue trauma. The objectives of this study are to investigate a novel method of magnetisation of bowel segments by intraluminal injection of magnetic glue and to demonstrate the feasibility of magnetic retraction of bowel with sufficient force during minimal access surgery. Following an initial materials characterisation study, selected microparticles of stainless steel (SS410-μPs were mixed with chosen cyanoacrylate glue (Loctite 4014. During intraluminal injection of the magnetic glue using ex vivo porcine colonic segments, a magnetic probe placed at the injected site ensured that the SS410-μPs aggregated during glue polymerisation to form an intraluminal mucosally adherent coagulum. The magnetised colonic segments were retracted by magnetic probes (5 and 10 mm placed external to the bowel wall. A tensiometer was used to record the retraction force. With an injected volume of 2 mL in a particle concentration of 1 g/mL, this technique produced maximal magnetic retraction forces of 2.24 ± 0.23 N and 5.11 ± 0.34 N (, with use of 5 and 10 mm probes, respectively. The results indicate that the formation of an intraluminal coagulum based on SS410-μPs and Loctite 4014 produces sufficient magnetic retraction for bowel retraction.

  2. Occurrence of chronic esophageal ulcer after high dose rate intraluminal radiation therapy for esophageal cancer

    International Nuclear Information System (INIS)

    Soejima, Toshinori; Hirota, Saeko; Okamoto, Yoshiaki; Obayashi, Kayoko; Takada, Yoshiki

    1995-01-01

    Ninety-eight patients with esophageal cancer were treated by high dose rate intraluminal radiation therapy at the Department of Radiology of the Hyogo Medical Center for Adults between January 1982 and December 1993. Twenty patients with complete response after intraluminal radiation therapy, who were followed up with esophageal fiberscopy in our institute, were reviewed. The one-year cumulative rate of occurrence of esophageal ulcers was 81%, and in 69% of the cases the ulcers occurred from 4 to 8 months after completion of intraluminal radiation therapy. We graded esophageal ulcer by fiberscopic findings. Grade 0 was defined as no ulcer, grade 1 as superficial ulcer, grade 2 as deep ulcer, grade 3 as circumferencial ulcer, and severe stenosis. Factors related to grade were studied, and shorter distances from the source to the surface of the mucosa and lower surface doses of intraluminal radiation therapy appear to reduce the severity as graded on the above scale, of the esophageal ulcer. Four of the five 2-year recurrence-free patients suffered esophageal ulcers, which were cured from 15 to 22 months after intraluminal radiation therapy. However ulcers recurred in two patients, ong term care was thought to be necessary. (author)

  3. Respiratory impedance is correlated with airway narrowing in asthma using three-dimensional computed tomography.

    Science.gov (United States)

    Karayama, M; Inui, N; Mori, K; Kono, M; Hozumi, H; Suzuki, Y; Furuhashi, K; Hashimoto, D; Enomoto, N; Fujisawa, T; Nakamura, Y; Watanabe, H; Suda, T

    2018-03-01

    Respiratory impedance comprises the resistance and reactance of the respiratory system and can provide detailed information on respiratory function. However, details of the relationship between impedance and morphological airway changes in asthma are unknown. We aimed to evaluate the correlation between imaging-based airway changes and respiratory impedance in patients with asthma. Respiratory impedance and spirometric data were evaluated in 72 patients with asthma and 29 reference subjects. We measured the intraluminal area (Ai) and wall thickness (WT) of third- to sixth-generation bronchi using three-dimensional computed tomographic analyses, and values were adjusted by body surface area (BSA, Ai/BSA, and WT/the square root (√) of BSA). Asthma patients had significantly increased respiratory impedance, decreased Ai/BSA, and increased WT/√BSA, as was the case in those without airflow limitation as assessed by spirometry. Ai/BSA was inversely correlated with respiratory resistance at 5 Hz (R5) and 20 Hz (R20). R20 had a stronger correlation with Ai/BSA than did R5. Ai/BSA was positively correlated with forced expiratory volume in 1 second/forced vital capacity ratio, percentage predicted forced expiratory volume in 1 second, and percentage predicted mid-expiratory flow. WT/√BSA had no significant correlation with spirometry or respiratory impedance. Respiratory resistance is associated with airway narrowing. © 2018 John Wiley & Sons Ltd.

  4. Randomized clinical trial of biodegradeable intraluminal sheath to prevent anastomotic leak after stapled colorectal anastomosis

    NARCIS (Netherlands)

    Bakker, I S; Morks, A N; Ten Cate Hoedemaker, H O; Burgerhof, J G M; Leuvenink, H G; van Praagh, J B; Ploeg, R J; Havenga, K

    Background: Anastomotic leakage is a potential major complication after colorectal surgery. The C-seal was developed to help reduce the clinical leakage rate. It is an intraluminal sheath that is stapled proximal to a colorectal anastomosis, covering it intraluminally and thus preventing intestinal

  5. Atg9 is required for intraluminal vesicles in amphisomes and autolysosomes

    Directory of Open Access Journals (Sweden)

    C. A. Bader

    2015-11-01

    Full Text Available Autophagy is an intracellular recycling and degradation process, which is important for energy metabolism, lipid metabolism, physiological stress response and organism development. During Drosophila development, autophagy is up-regulated in fat body and midgut cells, to control metabolic function and to enable tissue remodelling. Atg9 is the only transmembrane protein involved in the core autophagy machinery and is thought to have a role in autophagosome formation. During Drosophila development, Atg9 co-located with Atg8 autophagosomes, Rab11 endosomes and Lamp1 endosomes-lysosomes. RNAi silencing of Atg9 reduced both the number and the size of autophagosomes during development and caused morphological changes to amphisomes/autolysosomes. In control cells there was compartmentalised acidification corresponding to intraluminal Rab11/Lamp-1 vesicles, but in Atg9 depleted cells there were no intraluminal vesicles and the acidification was not compartmentalised. We concluded that Atg9 is required to form intraluminal vesicles and for localised acidification within amphisomes/autolysosomes, and consequently when depleted, reduced the capacity to degrade and remodel gut tissue during development.

  6. Palliation in esophageal cancer with a single session of intraluminal irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Jager, J.J.; Pannebakker, M.; Vos, J. de (Radiotherapeutic Institute Limburg, Heerlen (Netherlands)); Rijken, J. (De Wever Hospital, Heerlen (Netherlands). Department of Internal Medicine); Vismans, F.J.F.E. (University Hospital Maastricht (Netherlands). Department of Gastroenterology)

    1992-10-01

    From September 1987-December 1989, 36 patients with advanced esophageal cancer entered a study in order to determine the efficacy of palliation by a single session of intraluminal irradiation. A dose of 15 Gy was administered at 1 cm distance from the central axis of the applicator. In 22 of 32 patients alive at least 6 weeks after treatment dysphagia improved, in 14 this relief was complete. Re-obstruction occurred in 8 of the 36 patients. Intraluminal irradiation is easy to administer and safe, it forms a useful addition to the therapeutic possibilities for the palliation of esophageal cancer. (author). 12 refs., 2 figs., 1 tab.

  7. Angioplasty of symptomatic high-grade internal carotid artery stenosis with intraluminal thrombus: therapeutic approach

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, A.; Mayol, A. [Seccion de Neurorradiologia Intervencionista, Servicio de Radiologia, Hospital Universitario Virgen del Rocio, Avenida Manuel Siurot s/n, Avenida Manuel Siurot s/n, 41013, Sevilla (Spain); Gil-Peralta, A.; Gonzalez-Marcos, J.R. [Servicio de Neurologia, Hospital Universitario Virgen del Rocio, Avenida Manuel Siurot s/n, 41013, Sevilla (Spain); Boza, F. [Servicio de Neurofisiologia, Hospital Universitario Virgen del Rocio, Avenida Manuel Siurot s/n, 41013, Sevilla (Spain); Ruano, J. [Unidad de Cuidados Intensivos, Hospital Universitario Virgen del Rocio, Avenida Manuel Siurot s/n, 41013, Sevilla (Spain)

    2004-04-01

    Intraluminal thrombus in the internal carotid artery (ICA) is usually found in patients with severe atheromatous stenosis. Having reviewed 300 carotid angioplasties for symptomatic >70% ICA stenosis, we found three patients (1%) with intraluminal thrombus. Conservative treatment with anticoagulants and double antiplatelet coverage can result in lysis of the thrombus without severe risks. Percutaneous transluminal angioplasty and stenting, preferably with distal protection, can be an excellent alternative to carotid endarterectomy. (orig.)

  8. Sutureless choledochoduodenostomy with an intraluminal degradable stent in dog model

    Institute of Scientific and Technical Information of China (English)

    ZHU Ling-hua; LIANG Xiao; LIN Hui; WANG Yi-fan; ZHU Yi-ping; CAI Xiu-jun

    2011-01-01

    Background It is difficult and time-consuming for carrying out conventional hand-sewn bilioenteric anastomosis, especially for small bile duct anastomosis and laparoscopic procedure. In order to simplify it, we have developed a novel procedure of sutureless bilioenteric anastomosis with an intraluminal degradable stent. This study aimed to evaluate the feasibility and safety of this technique with cholangioduodenostomy in dog model.Methods A patent intraluminal degradable stent tube for sutureless choledochoduodenostomy in dog model was made with polylactic acid in diameter of 3 mm or 4 mm. Thirty-eight dogs were randomly divided into to a stent group (SG, n=20) and a control group (CG, n=18). Dogs in the SG underwent sutureless choledochoduodenostomy with intraluminal stent, while the CG underwent conventional choledochoduodenostomy (single layer discontinuous anastomosis with absorbable suture). Dogs of each group were divided into 4 subgroups according to time of death (1,3,6, and 12 months postoperatively) to evaluate the healing of anastomosis. Operation time, intraoperative tolerance pressure of anastomosis, rate of postoperative bile leakage, bursting pressure of anastomosis were compared between the two groups. Anastomosis tissue was observed afterwards by pathology evaluation, hydroxyproline content, serum bilirubin, liver enzyme level and magnetic resonance cholangio-pancreatography (MRCP) to assess the stricture.Results All procedures were completed successfully. The surgical time of the SG was significantly less than the CG (SG: (19.2±4.3) minutes, vs. CG: (29.2±7.1) minutes, P=0.000). One bile leakage was occurred in either group. No significant difference of intraoperative tolerance pressure of anastomosis, rate of bile leakage and postoperative bursting pressure of anastomosis, anastomotic stricture, hydroxyproline content, serum bilirubin and liver enzyme level was found between the two groups. MRCP showed no anastomosis stricture and obstruction

  9. An expert panel-based study on recognition of gastro-esophageal reflux in difficult esophageal pH-impedance tracings

    NARCIS (Netherlands)

    Smits, M. J.; Loots, C. M.; van Wijk, M. P.; Bredenoord, A. J.; Benninga, M. A.; Smout, A. J. P. M.

    2015-01-01

    Despite existing criteria for scoring gastro-esophageal reflux (GER) in esophageal multichannel pH-impedance measurement (pH-I) tracings, inter- and intra-rater variability is large and agreement with automated analysis is poor. To identify parameters of difficult to analyze pH-I patterns and

  10. Fallopian tube intraluminal tumor spread from noninvasive precursor lesions: a novel metastatic route in early pelvic carcinogenesis.

    Science.gov (United States)

    Bijron, Jonathan G; Seldenrijk, Cornelis A; Zweemer, Ronald P; Lange, Joost G; Verheijen, René H M; van Diest, Paul J

    2013-08-01

    Pelvic serous carcinoma is usually advanced stage at diagnosis, indicating that abdominal spread occurs early in carcinogenesis. Recent discovery of a precursor sequence in the fallopian tube, culminating in serous tubal intraepithelial carcinoma (STIC), provides an opportunity to study early disease events. This study aims to explore novel metastatic routes in STICs. A BRCA1 mutation carrier (patient A) who presented with a STIC and tubal intraluminal shedding of tumor cells upon prophylactic bilateral salpingo-oophorectomy (PBSO) instigated scrutiny of an additional 23 women who underwent a PBSO and 40 patients with pelvic serous carcinoma involving the tubes. Complete serial sectioning of tubes and ovaries of patient A did not reveal invasive carcinoma, but subsequent staging surgery showed disseminated abdominal disease. STIC, intraluminal tumor cells, and abdominal metastases displayed an identical immunohistochemical profile (p53/WT1/PAX8/PAX2) and TP53 mutation. In 16 serous carcinoma patients (40%) tubal intraluminal tumor cells were found, compared with none in the PBSO group. This is the first description of a STIC, which plausibly metastasized without the presence of invasion through intraluminal shedding of malignant surface epithelial cells in the tube and subsequently spread throughout the peritoneal cavity. These findings warrant a reconsideration of the malignant potential of STICs and indicate that intraluminal shedding could be a risk factor for early intraperitoneal metastasis. Although rare in the absence of invasive cancer, we show that intraluminal shedding of tumor cells in the fallopian tubes from serous carcinoma cases are common and a likely route of abdominal spread.

  11. 192Ir Intraluminal brachytherapy for the prevention of urethral re-stricture

    International Nuclear Information System (INIS)

    Ma Changuo; Guo Hui; Du Chun; Yang Keqiang

    2008-01-01

    Objective: To evaluate the safety and efficacy of 192 Ir intraluminal brachytherapy for the prevention of urethral restricture after transurethral incision or transurethral resection of scar. Methods: From Mar. 2004 to Jun. 2006, 48 patients aging 18-81 years were treated by 192 Ir intraluminal brachytherapy. The length of stricture(0.5-5.5 cm) was ≤3.0 cm in 90% of the patients. The stricture was caused by trauma in 23 patients and prostate hyperplasia operation in 19 patients. The cause of remaining 6 patients was unclear. All patients were diagnosed by urethra photograph or endoscopy. Radiotherapy was the initial treatment in 26 patients and the second time treatment in 22. The irradiation dose was from 14 Gy to 18 Gy. Results: The median follow up was 10 months, and the total response rate was 98%. Only one patient recurred and received transurethral incision again. The uresis was fluency in 47 patients and the maximum flow rate was 13.9-36.4 (19.2 ± 10.3) ml/s. No secondary urethral bleeding or urethral cancer was observed. Conclusions: Being a safe and feasible treatment, 192 Ir intraluminal brachytherapy following transurethral incision or transurethral resection of scar can effectively prevent urethral re-stricture. (authors)

  12. Flat Engineered Multichannel Reflectors

    Directory of Open Access Journals (Sweden)

    V. S. Asadchy

    2017-09-01

    Full Text Available Recent advances in engineered gradient metasurfaces have enabled unprecedented opportunities for light manipulation using optically thin sheets, such as anomalous refraction, reflection, or focusing of an incident beam. Here, we introduce a concept of multichannel functional metasurfaces, which are able to control incoming and outgoing waves in a number of propagation directions simultaneously. In particular, we reveal a possibility to engineer multichannel reflectors. Under the assumption of reciprocity and energy conservation, we find that there exist three basic functionalities of such reflectors: specular, anomalous, and retroreflections. Multichannel response of a general flat reflector can be described by a combination of these functionalities. To demonstrate the potential of the introduced concept, we design and experimentally test three different multichannel reflectors: three- and five-channel retroreflectors and a three-channel power splitter. Furthermore, by extending the concept to reflectors supporting higher-order Floquet harmonics, we forecast the emergence of other multichannel flat devices, such as isolating mirrors, complex splitters, and multi-functional gratings.

  13. Flat Engineered Multichannel Reflectors

    Science.gov (United States)

    Asadchy, V. S.; Díaz-Rubio, A.; Tcvetkova, S. N.; Kwon, D.-H.; Elsakka, A.; Albooyeh, M.; Tretyakov, S. A.

    2017-07-01

    Recent advances in engineered gradient metasurfaces have enabled unprecedented opportunities for light manipulation using optically thin sheets, such as anomalous refraction, reflection, or focusing of an incident beam. Here, we introduce a concept of multichannel functional metasurfaces, which are able to control incoming and outgoing waves in a number of propagation directions simultaneously. In particular, we reveal a possibility to engineer multichannel reflectors. Under the assumption of reciprocity and energy conservation, we find that there exist three basic functionalities of such reflectors: specular, anomalous, and retroreflections. Multichannel response of a general flat reflector can be described by a combination of these functionalities. To demonstrate the potential of the introduced concept, we design and experimentally test three different multichannel reflectors: three- and five-channel retroreflectors and a three-channel power splitter. Furthermore, by extending the concept to reflectors supporting higher-order Floquet harmonics, we forecast the emergence of other multichannel flat devices, such as isolating mirrors, complex splitters, and multi-functional gratings.

  14. Intraluminal erosion of laparoscopic gastric band tubing into duodenum with recurrent port-site infections.

    Science.gov (United States)

    Cintolo, Jessica A; Levine, Marc S; Huang, Stephanie; Dumon, Kristoffel

    2012-01-01

    Intraluminal erosion of a laparoscopic gastric band into the stomach has been reported as a complication of laparoscopic adjustable gastric banding. To our knowledge, however, intraluminal erosion of the band tubing into the duodenum has not been described. We report a 46-year-old man in whom a laparoscopic adjustable gastric band tubing eroded into the duodenal lumen, causing recurrent port-site infections. This complication was diagnosed on upper endoscopy and also, in retrospect, on an upper gastrointestinal barium study and computed tomography. The patient underwent surgical removal of the band and tubing, with a primary duodenal repair, and made a complete recovery without complications. Erosion of laparoscopic band tubing into the duodenum should be included in the differential diagnosis for recurrent port-site infections after laparoscopic adjustable gastric banding. Radiographic or endoscopic visualization of the intraluminal portion of the tubing may be required for confirmation. Definitive treatment of this complication entails surgical removal of the tubing from the duodenum.

  15. Intraluminal Administration of Poly I:C Causes an Enteropathy That Is Exacerbated by Administration of Oral Dietary Antigen

    Science.gov (United States)

    Araya, Romina E.; Jury, Jennifer; Bondar, Constanza

    2014-01-01

    Systemic administration of polyinosinic:polycytidylic acid (poly I:C), mimics virally-induced activation of TLR3 signalling causing acute small intestine damage, but whether and how mucosal administration of poly I:C causes enteropathy is less clear. Our aim was to investigate the inflammatory pathways elicited after intraluminal administration of poly I:C and determine acute and delayed consequences of this locally induced immune activation. Intraluminal poly I:C induced rapid mucosal immune activation in C57BL/6 mice involving IFNβ and the CXCL10/CXCR3 axis, that may drive inflammation towards a Th1 profile. Intraluminal poly I:C also caused enteropathy and gut dysfunction in gliadin-sensitive NOD-DQ8 mice, and this was prolonged by concomitant oral administration of gliadin. Our results indicate that small intestine pathology can be induced in mice by intraluminal administration of poly I:C and that this is exacerbated by subsequent oral delivery of a relevant dietary antigen. PMID:24915573

  16. Determination of time delay between ventricles contraction using impedance measurements

    International Nuclear Information System (INIS)

    Lewandowska, M; Poliński, A; Wtorek, J

    2013-01-01

    The paper presents a novel approach to assessment of ventricular dyssynchrony basing on multichannel electrical impedance measurements. Using a proper placement of electrodes, the sensitivity approach allows estimating time difference between chambers contraction from over determined nonlinear system of equations. The theoretical considerations which include Finite Element Method simulations were verified using measurements on healthy 28 year's old woman. The nonlinear least squares method was applied to obtain a time difference between heart chambers contraction. The obtained value was in a good agreement with theoretical values found in literature.

  17. Extrahepatic bile duct carcinoma treated by intraluminal irradiation with iridium-192 wire

    International Nuclear Information System (INIS)

    Ikeda, Hiro; Kuroda, Tomosumi; Uchida, Hideo

    1980-01-01

    A 57-year-old male with obstructive jaundice was diagnosed extrahepatic bile duct carcinoma at bifurcation by percutaneous transhepatic cholangiography (PTC). He was treated 3,300 rad of external irradiation and then intraluminal irradiation using the Iridium-192 wire by two times with the aid of PTC internal drainage, each was given by the dose of 1,600 rad at 5 mm inside the tumor from the PTC-tube. He had been well for about 1 year and then died because of ascites and cachexia. Autopsy revealed only microscopic tumor cells remaining around the common duct below the cystic junction. It was confirmed that intraluminal irradiation using the Iridium-192 wire was potentially curable and easily applicable to the bile duct carcinoma. (author)

  18. Multichannel waveform display system

    International Nuclear Information System (INIS)

    Kolvankar, V.G.

    1989-01-01

    For any multichannel data acquisition system, a multichannel paper chart recorder undoubtedly forms an essential part of the system. When deployed on-line, it instantaneously provides, for visual inspection, hard copies of the signal waveforms on common time base at any desired sensitivity and time resolution. Within the country, only a small range of these strip chart recorder s is available, and under stringent specifications imported recorders are often procured. The cost of such recorders may range from 1 to 5 lakhs of rupees in foreign exchange. A system to provide on the oscilloscope a steady display of multichannel waveforms, refreshed from the digital data stored in the memory is developed. The merits and demerits of the display system are compared with that built around a conventional paper chart recorder. Various illustrations of multichannel seismic event data acquired at Gauribidanur seismic array station are also presented. (author). 2 figs

  19. Skin Impedance Measurements for Acupuncture Research: Development of a Continuous Recording System

    Directory of Open Access Journals (Sweden)

    Agatha P. Colbert

    2008-01-01

    Full Text Available Skin impedance at acupuncture points (APs has been used as a diagnostic/therapeutic aid for more than 50 years. Currently, researchers are evaluating the electrophysiologic properties of APs as a possible means of understanding acupuncture's mechanism. To comprehensively assess the diagnostic, therapeutic and mechanistic implications of acupuncture point skin impedance, a device capable of reliably recording impedances from 100 kΩ to 50 MΩ at multiple APs over extended time periods is needed. This article describes design considerations, development and testing of a single channel skin impedance system (hardware, control software and customized electrodes. The system was tested for accuracy against known resistors and capacitors. Two electrodes (the AMI and the ORI were compared for reliability of recording over 30 min. Two APs (LU 9 and PC 6 and a nearby non-AP site were measured simultaneously in four individuals for 60 min. Our measurement system performed accurately (within 5% against known resistors (580 kΩ–10 MΩ and capacitors (10 nF–150 nF. Both the AMI electrode and the modified ORI electrode recorded skin impedance reliably on the volar surface of the forearm (r = 0.87 and r = 0.79, respectively. In four of four volunteers tested, skin impedance at LU 9 was less than at the nearby non-AP site. In three of four volunteers skin impedance was less at PC 6 than at the nearby non-AP site. We conclude that our system is a suitable device upon which we can develop a fully automated multi-channel device capable of recording skin impedance at multiple APs simultaneously over 24 h.

  20. Intraluminal polyethylene glycol stabilizes tight junctions and improves intestinal preservation in the rat.

    Science.gov (United States)

    Oltean, M; Joshi, M; Björkman, E; Oltean, S; Casselbrant, A; Herlenius, G; Olausson, M

    2012-08-01

    Rapidly progressing mucosal breakdown limits the intestinal preservation time below 10 h. Recent studies indicate that intraluminal solutions containing polyethylene glycol (PEG) alleviate preservation injury of intestines stored in UW-Viaspan. We investigated whether a low-sodium PEG solution is beneficial for intestines stored in histidine-tryptophane-ketoglutarate (HTK) preservation solution. Rat intestines used as control tissue (group 1) were perfused with HTK, groups 2 and 3 received either a customized PEG-3350 (group 2) or an electrolyte solution (group 3) intraluminally before cold storage. Tissue injury, brush-border maltase activity, zonula occludens-1 (ZO-1) and claudin-3 expression in the tight junctions (TJ) were analyzed after 8, 14 and 20 h. We measured epithelial resistance and permeability (Ussing chamber) after 8 and 14 h. Group 2 had superior morphology while maltase activity was similar in all groups. TJ proteins rapidly decreased and decolocalized in groups 1 3; these negative events were delayed in group 2, where colocalization persisted for about 14 h. Intestines in group 2 had higher epithelial resistance and lower permeability than the other groups. These results suggest that a customized PEG solution intraluminally reduces the intestinal preservation injury by improving several major epithelial characteristics without negatively affecting the brush-border enzymes or promoting edema. © Copyright 2012 The American Society of Transplantation and the American Society of Transplant Surgeons.

  1. Resultados a médio prazo do tratamento cirúrgico da dissecção aguda de aorta tipo A com o emprego da prótese intraluminal Surgical treatment of type a aortic dissection using intraluminal prosthesis medium term follow up

    Directory of Open Access Journals (Sweden)

    Jefferson Francisco de OLIVEIRA

    2001-06-01

    Full Text Available Introdução: O conceito de prótese intraluminal foi introduzido por CARREL, em 1912. Em 1978, DUREAU & ABLASA descreveram os primeiros casos de dissecção aguda de aorta tratados com o emprego da prótese intraluminal. Esta prótese foi utilizada nos anos 80 por vários grupos com bons resultados. Vários relatos de complicações (migração, embolias, estenoses, formação de pseudo-aneurismas fizeram com que os grupos cirúrgicos perdessem o entusiasmo por esta técnica. Objetivo: Avaliar a anastomose empregando a prótese intraluminal sem sutura no tratamento da dissecção aguda de aorta tipo A. Casuística e Métodos: Sessenta e quatro pacientes com diagnóstico de dissecção aguda de aorta do tipo A foram operados em nosso Serviço. Em todos os casos empregamos o anel intraluminal como técnica de sutura. A idade média dos pacientes era de 56,3 anos, sendo 57 (89% do sexo masculino. Todos os pacientes eram portadores de hipertensão arterial sistêmica. Em 26 pacientes utilizamos somente a anastomose intraluminal, com o anel proximal acima dos óstios coronários de modo a ressuspender a valva aórtica e o anel distal posicionado junto à origem do tronco braquiocefálico. O tempo médio de pinçamento da aorta nestes pacientes foi de 9 minutos e o tempo médio de CEC de 26 minutos. Somente em 1 caso houve rotura da ligadura sobre o anel proximal, quando realizamos uma operação radical (Bentall- DeBonno, mantendo o anel distal. Em 23 pacientes utilizamos a ressuspensão da valva aórtica e o preparo da raiz da aorta com duplo retalho de Dacron, empregando o anel intraluminal na anastomose distal. Abordamos o arco aórtico em 8 pacientes. A troca da valva aórtica foi necessária em apenas 6 pacientes. A mortalidade global foi de 10,3%, sendo que nos pacientes onde foi possível o tratamento com o duplo anel não houve nenhum óbito. Na avaliação pós-operatória destes pacientes foi realizado ecocardiograma e aortografia. N

  2. Intraluminal proteome and peptidome of human urinary extracellular vesicles.

    Science.gov (United States)

    Liu, Xinyu; Chinello, Clizia; Musante, Luca; Cazzaniga, Marta; Tataruch, Dorota; Calzaferri, Giulio; James Smith, Andrew; De Sio, Gabriele; Magni, Fulvio; Zou, Hequn; Holthofer, Harry

    2015-06-01

    Urinary extracellular vesicles (UEVs) are a novel source for disease biomarker discovery. However, Tamm-Horsfall protein (THP) is still a challenge for proteomic analysis since it can inhibit detection of low-abundance proteins. Here, we introduce a new approach that does not involve an ultracentrifugation step to enrich vesicles and that reduces the amount of THP to manageable levels. UEVs were dialyzed and ultrafiltered after reduction and alkylation. The retained fraction was digested with trypsin to reduce the remaining THP and incubated with deoxycholate (DOC). The internal peptidome and internal proteome were analyzed by LC-ESI-MS. A total of 942 different proteins and 3115 unique endogenous peptide fragments deriving from 973 different protein isoforms were identified. Around 82% of the key endosomal sorting complex required for transport components of UEVs generation could be detected from the intraluminal content. Our UEVs preparation protocol provides a simplified way to investigate the intraluminal proteome and peptidome, in particular the subpopulation of UEVs of the trypsin-resistant class of exosomes (positive for tumor susceptibility gene101) and eliminates the majority of interfering proteins such as THP. This method allows the possibility to study endoproteome and endopeptidome of UEVs, thus greatly facilitating biomarker discovery. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. A 0.18 μm CMOS LDO Regulator for an On-Chip Sensor Array Impedance Measurement System.

    Science.gov (United States)

    Pérez-Bailón, Jorge; Márquez, Alejandro; Calvo, Belén; Medrano, Nicolás

    2018-05-02

    This paper presents a fully integrated 0.18 μm CMOS Low-Dropout (LDO) Voltage Regulator specifically designed to meet the stringent requirements of a battery-operated impedance spectrometry multichannel CMOS micro-instrument. The proposed LDO provides a regulated 1.8 V voltage from a 3.6 V to 1.94 V battery voltage over a −40 °C to 100 °C temperature range, with a compact topology (sensors.

  4. Intraluminal duodenal diverticulum: CT and gadoxetic acid-enhanced MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jeong Myeong; Lee, Nam Kyung; Kim, Suk; Kim, Dong Uk; Kim, Tae Un [Dept. of Radiology, Pusan National University Hospital, Pusan National University School of Medicine, Busan (Korea, Republic of)

    2015-03-15

    Intraluminal duodenal diverticulum (IDD) is a rare congenital anomaly. IDD can become symptomatic in 20% to 25% of cases when complicated by intestinal obstruction, pancreatitis, or hemorrhage. We report the case of a 21-year-old female presenting with IDD mimicking duodenoduodenal intussusception. We describe the imaging features of IDD on the gadoxetic acid-enhanced magnetic resonance image as well as computed tomography.

  5. Inhibition of early AAA formation by aortic intraluminal pentagalloyl glucose (PGG) infusion in a novel porcine AAA model

    DEFF Research Database (Denmark)

    Kloster, Brian O; Lund, Lars; Lindholt, Jes S

    2016-01-01

    to prevent or delay their expansion. In this study, we investigated whether intraluminal delivered pentagalloyl glucose (PGG) can impair the early AAA development in a porcine model. METHODS: The infrarenal aorta was exposed in thirty pigs. Twenty underwent an elastase based AAA inducing procedure and ten...... of these received an additional intraluminal PGG infusion. The final 10 were sham operated and served as controls. RESULTS: All pigs who only had an elastase infusion developed macroscopically expanding AAAs. In pigs treated with an additional PGG infusion the growth rate of the AP-diameter rapidly returned...... and histology. CONCLUSION: In our model, intraluminal delivered PGG is able to penetrate the aortic wall from the inside and impair the early AAA development by stabilizing the elastic lamellae and preserving their integrity. The principle holds a high clinical potential if it can be translated to human...

  6. Virtual Microphones for Multichannel Audio Resynthesis

    Directory of Open Access Journals (Sweden)

    Athanasios Mouchtaris

    2003-09-01

    Full Text Available Multichannel audio offers significant advantages for music reproduction, including the ability to provide better localization and envelopment, as well as reduced imaging distortion. On the other hand, multichannel audio is a demanding media type in terms of transmission requirements. Often, bandwidth limitations prohibit transmission of multiple audio channels. In such cases, an alternative is to transmit only one or two reference channels and recreate the rest of the channels at the receiving end. Here, we propose a system capable of synthesizing the required signals from a smaller set of signals recorded in a particular venue. These synthesized “virtual” microphone signals can be used to produce multichannel recordings that accurately capture the acoustics of that venue. Applications of the proposed system include transmission of multichannel audio over the current Internet infrastructure and, as an extension of the methods proposed here, remastering existing monophonic and stereophonic recordings for multichannel rendering.

  7. Intraluminal bubble dynamics induced by lithotripsy shock wave

    Science.gov (United States)

    Song, Jie; Bai, Jiaming; Zhou, Yufeng

    2016-12-01

    Extracorporeal shock wave lithotripsy (ESWL) has been the first option in the treatment of calculi in the upper urinary tract since its introduction. ESWL-induced renal injury is also found after treatment and is assumed to associate with intraluminal bubble dynamics. To further understand the interaction of bubble expansion and collapse with the vessel wall, the finite element method (FEM) was used to simulate intraluminal bubble dynamics and calculate the distribution of stress in the vessel wall and surrounding soft tissue during cavitation. The effects of peak pressure, vessel size, and stiffness of soft tissue were investigated. Significant dilation on the vessel wall occurs after contacting with rapid and large bubble expansion, and then vessel deformation propagates in the axial direction. During bubble collapse, large shear stress is found to be applied to the vessel wall at a clinical lithotripter setting (i.e. 40 MPa peak pressure), which may be the mechanism of ESWL-induced vessel rupture. The decrease of vessel size and viscosity of soft tissue would enhance vessel deformation and, consequently, increase the generated shear stress and normal stresses. Meanwhile, a significantly asymmetric bubble boundary is also found due to faster axial bubble expansion and shrinkage than in radial direction, and deformation of the vessel wall may result in the formation of microjets in the axial direction. Therefore, this numerical work would illustrate the mechanism of ESWL-induced tissue injury in order to develop appropriate counteractive strategies for reduced adverse effects.

  8. Essays on multichannel customer management

    NARCIS (Netherlands)

    Konus, U.

    2010-01-01

    The main goal of this dissertation is to gain a greater understanding of multichannel customer behavior and how firms can manage their multichannel marketing activities. The first study reveals that three customer segments can be identified based on their orientation towards using multiple channels

  9. Multi-channel polarized thermal emitter

    Science.gov (United States)

    Lee, Jae-Hwang; Ho, Kai-Ming; Constant, Kristen P

    2013-07-16

    A multi-channel polarized thermal emitter (PTE) is presented. The multi-channel PTE can emit polarized thermal radiation without using a polarizer at normal emergence. The multi-channel PTE consists of two layers of metallic gratings on a monolithic and homogeneous metallic plate. It can be fabricated by a low-cost soft lithography technique called two-polymer microtransfer molding. The spectral positions of the mid-infrared (MIR) radiation peaks can be tuned by changing the periodicity of the gratings and the spectral separation between peaks are tuned by changing the mutual angle between the orientations of the two gratings.

  10. Clinical result of high-dose rate intraluminal brachytherapy for esophageal carcinoma with a remote afterloading system

    International Nuclear Information System (INIS)

    Fukuda, Haruyuki; Nakajima, Toshifumi; Tada, Takuhito; Tanaka, Masahiro; Tsumura, Masashi; Onoyama, Yasuto

    1992-01-01

    During the period from 1977 through 1987, 105 patients with esophageal carcinoma were radically treated by radiotherapy. Forty-six patients receiving therapy before August 1982 were all treated by external beam therapy alone (Group 1). Since September 1982, 26 patients were treated by external beam therapy alone (Group 2) and 33 patients were treated by high-dose-rate intraluminal brachytherapy with a remote afterloading system combined with external beam therapy (Group 3). Dose of external beam therapy for Group 1, Group 2 and Group 3 patients were 66.7 Gy, 68.7 Gy and 55.9 Gy on the average. The intraluminal brachytherapy was performed with a total dose of 12 Gy consisting of 3 Gy twice a week. Ten of 72 patients (14%) treated by external beam therapy alone achieved complete response, whereas 14 of 33 patients (42%) treated by high-dose-rate intraluminal brachytherapy combined with external beam therapy had complete response. One-, and 3-year survival rates were 36% and 10% in the Group 1, 32% and 12% in the Group 2 and 56% and 36% in the Group 3. For Group 3, good survival rate was obtained in tumorous type and serrated type. Patients with tumor of less than 5 cm in Group 3 had good survival. The data suggest that the high-dose-rate intraluminal bracytherapy prescribed as a boost therapy following external beam therapy is an effective therapy modality for esophageal carcinoma which is of non-circumferential tumor or less than 5 cm. (author)

  11. Design of a wideband CMOS impedance spectroscopy ASIC analog front-end for multichannel biosensor interfaces.

    Science.gov (United States)

    Valente, Virgilio; Dai Jiang; Demosthenous, Andreas

    2015-08-01

    This paper presents the preliminary design and simulation of a flexible and programmable analog front-end (AFE) circuit with current and voltage readout capabilities for electric impedance spectroscopy (EIS). The AFE is part of a fully integrated multifrequency EIS platform. The current readout comprises of a transimpedance stage and an automatic gain control (AGC) unit designed to accommodate impedance changes larger than 3 order of magnitude. The AGC is based on a dynamic peak detector that tracks changes in the input current over time and regulates the gain of a programmable gain amplifier in order to optimise the signal-to-noise ratio. The system works up to 1 MHz. The voltage readout consists of a 2 stages of fully differential current-feedback instrumentation amplifier which provide 100 dB of CMRR and a programmable gain up to 20 V/V per stage with a bandwidth in excess of 10MHz.

  12. Modeling High-Dimensional Multichannel Brain Signals

    KAUST Repository

    Hu, Lechuan; Fortin, Norbert J.; Ombao, Hernando

    2017-01-01

    aspects: first, there are major statistical and computational challenges for modeling and analyzing high-dimensional multichannel brain signals; second, there is no set of universally agreed measures for characterizing connectivity. To model multichannel

  13. Idiopathic pulmonary fibrosis is associated with increased impedance measures of reflux compared to non-fibrotic disease among pre-lung transplant patients.

    Science.gov (United States)

    Gavini, S; Finn, R T; Lo, W-K; Goldberg, H J; Burakoff, R; Feldman, N; Chan, W W

    2015-09-01

    Gastroesophageal reflux (GER) has been associated with idiopathic pulmonary fibrosis (IPF), although the mechanism remains unclear. Gastroesophageal reflux/microaspiration may lead to lung fibrosis, while increased pulmonary workload may also worsen GER. Comparing the GER profile of IPF patients to chronic obstructive pulmonary disease (COPD) patients with similar lung function may help delineate the role of GER in IPF pathogenesis. This was a retrospective cohort study of IPF and COPD patients undergoing pre-lung transplant multichannel intraluminal impedance and pH study (MII-pH) off acid suppression at a tertiary center in 2008-2014. Patients with prior fundoplication were excluded. Baseline demographics, pulmonary function test, and MII-pH results were recorded. Univariate analyses were performed using Fisher's exact (binary variables) and Student's t (continuous variables) tests. Logistic regression was performed to adjust for potential confounders. A total of 90 subjects (54 IPF, 36 COPD) met inclusion criteria. Compared to COPD, IPF patients had increased total reflux episodes (65.9 vs 46.1, p = 0.02), proximal reflux episodes (30.3 vs 20.3, p = 0.04), and prevalence of abnormal total reflux episodes (38.9% vs 16.7%, p = 0.02). On multivariate analyses, abnormal total reflux episodes (OR: 4.9, p = 0.05) and bolus reflux exposure time (OR: 4, p = 0.04) remained significantly associated with IPF. Abnormal reflux was significantly more prevalent among IPF patients after controlling for lung disease severity. Gastroesophageal reflux/microaspiration likely plays a role in fibrosis in IPF. A significant portion of IPF patients had increased non-acid reflux. Therapies aiming to prevent reflux of gastric contents may be more beneficial than antisecretory medications alone in these patients. © 2015 John Wiley & Sons Ltd.

  14. Gastro-esophageal reflux and antisecretory drugs use among patients with chronic autoimmune atrophic gastritis: a study with pH-impedance monitoring.

    Science.gov (United States)

    Tenca, A; Massironi, S; Pugliese, D; Consonni, D; Mauro, A; Cavalcoli, F; Franchina, M; Spampatti, M; Conte, D; Penagini, R

    2016-02-01

    Patients with chronic autoimmune atrophic gastritis (CAAG) often refer digestive symptoms and are prescribed antisecretory medications. Aims were to investigate: (i) gastro-esophageal reflux (GER), (ii) psychopathological profile, (iii) frequency of use and clinical benefit of antisecretory drugs. Prospective observational study on 41 CAAG patients who underwent: 24 h multichannel intra-luminal impedance-pH (MII-pH) monitoring off-therapy, standardized medical interview and psychological questionnaire (i.e., SCL-90R). The medical interview was repeated at least 1 month after MII-pH in patients who were using antisecretory drugs. Statistical analysis was performed calculating median (10th-90th percentiles) and risk ratios (RR) with 95% confidence interval. Median intra-gastric pH was 6.2 (4.6-7.0). One patient had acid reflux (AC) associated with symptoms, five had increased total reflux number and four had symptoms associated to non-acid reflux (NA) (patients referred as 'GER positive'). Using patients 'GER negative' with normal SCL-90R as reference, the RR of being symptomatic in patients GER positive was 2.1 (1.1-4.1) if SCL-90R was normal and 0.9 (0.5-1.7) if it was altered (difference in RR significant being p = 0.04). Seventeen/28 (61%) symptomatic patients were on antisecretory drugs, which were stopped in 16 of them according to results of MII-pH and clinical evaluation after 574 days (48-796) showed that symptoms were unchanged. In patients with CAAG (i) AC reflux rarely occurred whereas increased NA reflux was not infrequent both being related to symptoms in some patients, (ii) psychopathological profile has a role in symptoms' occurrence, (iii) antisecretory drugs were generally inappropriately used and clinically ineffective. © 2015 John Wiley & Sons Ltd.

  15. Multichannel analog temperature sensing system

    International Nuclear Information System (INIS)

    Gribble, R.

    1985-08-01

    A multichannel system that protects the numerous and costly water-cooled magnet coils on the translation section of the FRX-C/T magnetic fusion experiment is described. The system comprises a thermistor for each coil, a constant current circuit for each thermistor, and a multichannel analog-to-digital converter interfaced to the computer

  16. Multichannel analyzer embedded in FPGA

    International Nuclear Information System (INIS)

    Garcia D, A.; Hernandez D, V. M.; Vega C, H. R.; Ordaz G, O. O.; Bravo M, I.

    2017-10-01

    Ionizing radiation has different applications, so it is a very significant and useful tool, which in turn can be dangerous for living beings if they are exposed to uncontrolled doses. However, due to its characteristics, it cannot be perceived by any of the senses of the human being, so that in order to know the presence of it, radiation detectors and additional devices are required to quantify and classify it. A multichannel analyzer is responsible for separating the different pulse heights that are generated in the detectors, in a certain number of channels; according to the number of bits of the analog to digital converter. The objective of the work was to design and implement a multichannel analyzer and its associated virtual instrument, for nuclear spectrometry. The components of the multichannel analyzer were created in VHDL hardware description language and packaged in the Xilinx Vivado design suite, making use of resources such as the ARM processing core that the System on Chip Zynq contains and the virtual instrument was developed on the LabView programming graphics platform. The first phase was to design the hardware architecture to be embedded in the FPGA and for the internal control of the multichannel analyzer the application was generated for the ARM processor in C language. For the second phase, the virtual instrument was developed for the management, control and visualization of the results. The data obtained as a result of the development of the system were observed graphically in a histogram showing the spectrum measured. The design of the multichannel analyzer embedded in FPGA was tested with two different radiation detection systems (hyper-pure germanium and scintillation) which allowed determining that the spectra obtained are similar in comparison with the commercial multichannel analyzers. (Author)

  17. Modelling customer behaviour in multi-channel service distribution

    NARCIS (Netherlands)

    Heinhuis, D.; de Vries, E.J.; Kundisch, D.; Veit, D.J.; Weitzel, T.; Weinhardt, C.

    2009-01-01

    Financial service providers are innovating their distribution strategy into multi-channel strategies. The success of a multi-channel approach and the high investments made in information systems and enterprise architectures depends on the adoption and multi-channel usage behaviour of consumers. We

  18. The Effects of Switching to Vonoprazan, a Novel Potassium-Competitive Acid Blocker, on Gastric Acidity and Reflux Patterns in Patients with Erosive Esophagitis Refractory to Proton Pump Inhibitors.

    Science.gov (United States)

    Yamashita, Hiroshi; Kanamori, Atsushi; Kano, Chise; Hashimura, Hiroki; Matsumoto, Kei; Tsujimae, Masahiro; Yoshizaki, Tetsuya; Momose, Kenji; Obata, Daisuke; Eguchi, Takaaki; Fujita, Mikio; Okada, Akihiko

    2017-01-01

    The effects of vonoprazan and proton pump inhibitors (PPIs) in patients with reflux esophagitis (RE) have not yet been compared using multichannel intraluminal impedance-pH (MII-pH). A total of 8 patients with persistent gastric mucosal injury, despite completing an 8-week standard PPI therapy, were enrolled in the study. While they were on standard PPI therapy, the baseline values of reflux parameters, holding time ratio (HTR) of gastric pH >4, and esophageal pH 4 HTR was observed, from 26.5 to 78.0% (p = 0.029). A reduction in esophageal pH acid clearance time and the total number of reflux events, including acid and proximal reflux events, were significantly reduced. Vonoprazan may be a better therapy for the treatment of patients with PPI-refractory RE. © 2017 S. Karger AG, Basel.

  19. Three-dimensional black-blood contrast-enhanced MRI improves detection of intraluminal thrombi in patients with acute ischaemic stroke.

    Science.gov (United States)

    Jang, Won; Kwak, Hyo Sung; Chung, Gyung Ho; Hwang, Seung Bae

    2018-03-19

    This study evaluated the utility of three-dimensional (3D), black-blood (BB), contrast-enhanced, magnetic resonance imaging (MRI) for the detection of intraluminal thrombi in acute stroke patients. Forty-seven patients with acute stroke involving the anterior circulation underwent MRI examination within 6 h of clinical onset. Cerebral angiography was used as the reference standard. In a blinded manner, two neuroradiologists interpreted the following three data sets: (1) diffusion-weighted imaging (DWI) + 3D BB contrast-enhanced MRI; (2) DWI + susceptibility weighted imaging (SWI); (3) DWI + 3D BB contrast-enhanced MRI + SWI. Of these patients, 47 had clots in the middle cerebral artery and four had clots in the anterior cerebral artery. For both observers, the area under the curve (Az) for data sets 1 and 3, which included 3D BB contrast-enhanced MRI, was significantly greater than it was for data set 2, which did not include 3D BB contrast-enhanced MR imaging (observer 1, 0.988 vs 0.904, p = 0.001; observer 2, 0.988 vs 0.894, p = 0.000). Three-dimensional BB contrast-enhanced MRI improves detection of intraluminal thrombi compared to conventional MRI methods in patients with acute ischaemic stroke. • BB contrast-enhanced MRI helps clinicians to assess the intraluminal clot • BB contrast-enhanced MRI improves detection of intraluminal thrombi • BB contrast-enhanced MRI for clot detection has a higher sensitivity.

  20. Comparison of Esophageal Function Tests in Chinese Patients with Functional Heartburn and Reflux Hypersensitivity

    Directory of Open Access Journals (Sweden)

    Feng Gao

    2017-01-01

    Full Text Available Objective. To investigate the differences in the results of esophageal function tests for functional heartburn (FH and reflux hypersensitivity (RH. Methods. Patients with FH and RH and healthy volunteers (HVs from the Department of Gastroenterology, Beijing Anzhen Hospital and Beijing Chao-Yang hospital, who underwent high-resolution manometry and impedance (HRIM, and 24-hour multichannel intraluminal impedance and pH recording (MII/pH between 2014 and 2016, were enrolled in this study. Results. 36 HV, 147 FH patients, and 91 RH patients were enrolled. The postreflux swallow-induced peristaltic wave index (PSPW index and mean nocturnal baseline impedance (MNBI values were significantly lower in RH than in FH and HV. The ineffective esophageal motility (IEM, fragmented peristalsis rates, total bolus exposure, proximal total reflux events, and distal total reflux events were significantly greater in RH than in FH and HV. Conclusions. Compared to HV and FH patients, RH patients exhibited greater IEM and fragmented peristalsis rates, a greater total bolus exposure, more proximal total and distal total reflux events, and reduced chemical clearance and mucosal integrity. By using the above described parameters, HRIM and MII/pH assays could be used to correctly classify RH and FH and hence allow physicians to provide adequate relief from associated symptoms.

  1. Multichannel analyzer type CMA-3

    International Nuclear Information System (INIS)

    Czermak, A.; Jablonski, J.; Ostrowicz, A.

    1978-01-01

    Multichannel analyzer CMA-3 is designed for two-parametric analysis with operator controlled logical windows. It is implemented in CAMAC standard. A single crate contains all required modules and is controlled by the PDP-11/10 minicomputer. Configuration of CMA-3 is shown. CMA-3 is the next version of the multichannel analyzer described in report No 958/E-8. (author)

  2. Obligatory Role of Intraluminal O2− in Acute Endothelin-1 and Angiotensin II Signaling to Mediate Endothelial Dysfunction and MAPK Activation in Guinea-Pig Hearts

    Directory of Open Access Journals (Sweden)

    Emilia Wojtera

    2014-10-01

    Full Text Available We hypothesized that, due to a cross-talk between cytoplasmic O2−-sources and intraluminally expressed xanthine oxidase (XO, intraluminal O2− is instrumental in mediating intraluminal (endothelial dysfunction and cytosolic (p38 and ERK1/2 MAPKs phosphorylation manifestations of vascular oxidative stress induced by endothelin-1 (ET-1 and angiotensin II (AT-II. Isolated guinea-pig hearts were subjected to 10-min agonist perfusion causing a burst of an intraluminal O2−. ET-1 antagonist, tezosentan, attenuated AT-II-mediated O2−, indicating its partial ET-1 mediation. ET-1 and Ang-T (AT-II + tezosentan triggered intraluminal O2−, endothelial dysfunction, MAPKs and p47phox phosphorylation, and NADPH oxidase (Nox and XO activation. These effects were: (i prevented by blocking PKC (chelerythrine, Nox (apocynin, mitochondrial ATP-dependent K+ channel (5-HD, complex II (TTFA, and XO (allopurinol; (ii mimicked by the activation of Nox (NADH; and mitochondria (diazoxide, 3-NPA and (iii the effects by NADH were prevented by 5-HD, TTFA and chelerythrine, and those by diazoxide and 3-NPA by apocynin and chelerythrine, suggesting that the agonists coactivate Nox and mitochondria, which further amplify their activity via PKC. The effects by ET-1, Ang-T, NADH, diazoxide, and 3-NPA were opposed by blocking intraluminal O2− (SOD and XO, and were mimicked by XO activation (hypoxanthine. Apocynin, TTFA, chelerythrine, and SOD opposed the effects by hypoxanthine. In conclusion, oxidative stress by agonists involves cellular inside-out and outside-in signaling in which Nox-mitochondria-PKC system and XO mutually maintain their activities via the intraluminal O2−.

  3. Multi-channel mechanical test machine for HANARO (I)

    International Nuclear Information System (INIS)

    Song, M. S.; Choi, Y.; Cho, M. S.; Kim, B. G.; Kang, Y. H.

    2004-01-01

    Design and fabrication of multi-channel mechanical test machine is useful and important for the study of in-pile test of nuclear materials in HANARO. The dimension and shape of the multi-channel mechanical test machine should be fixed to a test reactor and their objectives. KAERI successfully developed a non-instrumented multi-channel mechanical test machine for material irradiation tests in a domestic research reactor, HANARO. This results in strongly stimulating and accelerating irradiation tests of materials in domestic industry and research fields with HANARO. Although various types of in-pile creep capsule were made for well installation in each test reactor, there is no in-pile creep multi-channel mechanical test machine for HANARO. Hence, the objectives of this study are to fabricate and test a multi-channel mechanical test machine of HANARO

  4. Extrahepatic bile duct carcinoma treated by intraluminal irradiation with iridium-192 wire. Report of a case

    Energy Technology Data Exchange (ETDEWEB)

    Ikeda, H; Kuroda, T; Uchida, H [Osaka Univ. (Japan). Faculty of Medicine

    1980-08-01

    A 57-year-old male with obstructive jaundice was diagnosed extrahepatic bile duct carcinoma at bifurcation by percutaneous transhepatic cholangiography (PTC). He was treated 3,300 rad of external irradiation and then intraluminal irradiation using the Iridium-192 wire by two times with the aid of PTC internal drainage, each was given by the dose of 1,600 rad at 5 mm inside the tumor from the PTC-tube. He had been well for about 1 year and then died because of ascites and cachexia. Autopsy revealed only microscopic tumor cells remaining around the common duct below the cystic junction. It was confirmed that intraluminal irradiation using the Iridium-192 wire was potentially curable and easily applicable to the bile duct carcinoma.

  5. Impedance Scaling and Impedance Control

    International Nuclear Information System (INIS)

    Chou, W.; Griffin, J.

    1997-06-01

    When a machine becomes really large, such as the Very Large Hadron Collider (VLHC), of which the circumference could reach the order of megameters, beam instability could be an essential bottleneck. This paper studies the scaling of the instability threshold vs. machine size when the coupling impedance scales in a ''normal'' way. It is shown that the beam would be intrinsically unstable for the VLHC. As a possible solution to this problem, it is proposed to introduce local impedance inserts for controlling the machine impedance. In the longitudinal plane, this could be done by using a heavily detuned rf cavity (e.g., a biconical structure), which could provide large imaginary impedance with the right sign (i.e., inductive or capacitive) while keeping the real part small. In the transverse direction, a carefully designed variation of the cross section of a beam pipe could generate negative impedance that would partially compensate the transverse impedance in one plane

  6. Normal appendix in adults: MDCT findings about the location, thickness and the presence or absence of intraluminal gas

    International Nuclear Information System (INIS)

    Oh, Kyoung Jin; Cho, June Sik; Shin, Kyung Sook; Kim, Ha Young; Lim, Sae Kyung; Ohm, Joon Young; Yoon, Chung Dae; Shin, Byung Seok

    2006-01-01

    We wanted to examine the usefulness of multi-detector CT (MDCT) with multiplanar reformations for evaluating the location, thickness and the presence or absence of intraluminal gas in the normal appendix of adults. From December 2004 to June 2005, we evaluated normal appendices in 427 consecutive adult patients who were scanned with 16-slice MDCT. All these patients had no clinical findings of appendicitis. There were 251 men and 176 women. The age range was 19-84 years (mean age: 55 years). The contrast-enhanced MDCT scans during the portal phase were obtained with 0.75 mm detector collimation and they were reviewed with using the multiplanar reconstruction images (3 mm section thickness). The MDCT images of normal appendices on a PACS monitor were retrospectively analyzed. We analyzed the location, thickness and the presence or absence of intraluminal gas by consensus of two abdominal radiologists. The positions of normal appendices were classified as type I (postileal and medial paracecal), type II (subcecal), type III (retrocecal and retrocolic or laterocolic), type IV (preileal and medical colic) and type V (lower pelvic cavity). The five types of appendiceal locations were as follows: type I (n = 187; 44%), type II (n 78; 18%), type III (n = 92, 22%), type IV (n = 39; 9%) and type V (n = 31; 7%). The appendiceal tips in 29 cases (7%) were unusually located in the right subhepatic space, the small bowel mesentery and the right adnexa. The mean thickness of 427 appendices was 5.8 ± 0.9 mm (range: 3.8-9.2 mm). The appendiceal mean thickness was 5.9 ± 0.9 mm in men and 5.7 ± 0.9 mm in women (ρ < 0.05). 384 (90%) of 427 appendices had intraluminal gas and 43 (10%) had no intraluminal gas, and their mean thickness was 5.9 mm (range: 3.8-9.2 mm) and 5.3 mm (3.8-7.3 mm), respectively (ρ < 0.05). MDCT with multiplanar reformations was useful for evaluating the location, thickness and the presence or absence of intraluminal gas in normal appendix of adults. These

  7. An updated review on gastro-esophageal reflux in pediatrics.

    Science.gov (United States)

    Vandenplas, Yvan; Hauser, Bruno

    2015-01-01

    Comprehensive guidelines for the diagnosis and management of gastro-esophageal reflux (GER) and GER disease (GERD) were developed by the European and North American Societies for Pediatric Gastroenterology, Hepatology and Nutrition. GERD is reflux associated with troublesome symptoms or complications. The recognition of GER and GERD is relevant to implement best management practices. A conservative management is indicated in infants with uncomplicated physiologic reflux. Children with GERD may benefit from further evaluation and treatment. Since the publications of the European and North American Societies for Pediatric Gastroenterology, Hepatology and Nutrition guidelines in 2009, no important novelties in drug treatment have been reported. Innovations are mainly restricted to the management of regurgitation in infants. During the last 5 years, pros and cons of multichannel intraluminal impedance have been highlighted. However, overall 'not much has changed' in the diagnosis and management of GER and GERD in infants and children.

  8. Lung disease severity in idiopathic pulmonary fibrosis is more strongly associated with impedance measures of bolus reflux than pH parameters of acid reflux alone.

    Science.gov (United States)

    Gavini, S; Borges, L F; Finn, R T; Lo, W-K; Goldberg, H J; Burakoff, R; Feldman, N; Chan, W W

    2017-05-01

    Gastroesophageal reflux (GER) has been associated with idiopathic pulmonary fibrosis (IPF). Pathogenesis may be related to chronic micro-aspiration. We aimed to assess objective measures of GER on multichannel intraluminal impedance and pH study (MII-pH) and their relationship with pulmonary function testing (PFT) results, and to compare the performance of pH/acid reflux parameters vs corresponding MII/bolus parameters in predicting pulmonary dysfunction in IPF. This was a retrospective cohort study of IPF patients undergoing prelung transplant evaluation with MII-pH off acid suppression, and having received PFT within 3 months. Patients with prior fundoplication were excluded. Severe pulmonary dysfunction was defined using diffusion capacity of the lung for carbon monoxide (DLCO) ≤40%. Six pH/acid reflux parameters with corresponding MII/bolus reflux measures were specified a priori. Multivariate analyses were applied using forward stepwise logistic regression. Predictive value of each parameter for severe pulmonary dysfunction was calculated by area-under-the-receiver-operating-characteristic-curve or c-statistic. Forty-five subjects (67% M, age 59, 15 mild-moderate vs 30 severe) met criteria for inclusion. Patient demographics and clinical characteristics were similar between pulmonary dysfunction groups. Abnormal total reflux episodes and prolonged bolus clearance time were significantly associated with pulmonary dysfunction severity on univariate and multivariate analyses. No pH parameters were significant. The c-statistic of each pH parameter was lower than its MII counterpart in predicting pulmonary dysfunction. MII/bolus reflux, but not pH/acid reflux, was associated with pulmonary dysfunction in prelung transplant patients with IPF. MII-pH may be more valuable than pH testing alone in characterizing GER in IPF. © 2016 John Wiley & Sons Ltd.

  9. The Bateman method for multichannel scattering theory

    International Nuclear Information System (INIS)

    Kim, Y. E.; Kim, Y. J.; Zubarev, A. L.

    1997-01-01

    Accuracy and convergence of the Bateman method are investigated for calculating the transition amplitude in multichannel scattering theory. This approximation method is applied to the calculation of elastic amplitude. The calculated results are remarkably accurate compared with those of exactly solvable multichannel model

  10. Multi-Detector CT Findings of the Normal Appendix in Children: Evaluation of the Position, Diameter, and Presence or Absence of Intraluminal Gas

    Energy Technology Data Exchange (ETDEWEB)

    Park, Woon Ju; Kim, Jong Chul [Dept. of Radiology, Chungnam National University College of Medicine, Daejeon (Korea, Republic of)

    2011-08-15

    To assess the usefulness of multi-detector CT (MDCT) with multiplanar reformations (MPR) for the evaluation of the position, diameter and presence or absence of intraluminal gas in the normal appendix in children. From 2007 to 2010, we retrospectively analyzed the MDCT images of normal appendices in 133 children, and evaluated the position, diameter, and presence or absence of intraluminal gas in the appendix. Among the 133 appendices, type I (postileal and medial paracecal position) was found in 64 children, type II (subcecal position) in 22, type III (retrocecal and retrocolic/laterocolic position) in 15, type IV (preileal and medial colic position) in 16, and type V (lower pelvic position) in 16 children. The mean diameter was 5.8 mm {+-} 1.2 (SD) (range; 3.2-8.7 mm). There was a high correlation between the appendiceal diameter and age (p = 0.000).There was no statistically significant difference in the appendiceal diameter between boys and girls (p = 0.470). Intraluminal gas was found in 115 appendices and there was no statistically significant correlation between the appendiceal diameter and intraluminal gas (p = 0.502). The MDCT with MPR was useful for the evaluation of the normal appendices in children. The procedure may be useful for the diagnosis of equivocal or unusual appendicitis in children.

  11. Multichannel strategy - the dominant approach in modern retailing

    Directory of Open Access Journals (Sweden)

    Stojković Dragan

    2016-01-01

    Full Text Available The purpose of this paper is to thoroughly analyse the concept of multichannel strategy, focussing on retail, to enable the academic community and marketers to better understand its advantages and disadvantages. This paper presents a comprehensive literature review and financial data analysis. The authors have analysed the financial data of 88 retail companies in the 2007 to 2014 period, and have proven that the importance of multichannel strategy has grown with the emergence of e-commerce. The main hypothesis is that the multichannel concept dominates modern marketing channels because it is widely accepted and provides superior financial performance. Multichannel retailing is definitely a winning concept, if adequately implemented. However, wrongly implemented it can negatively influence business performance.

  12. Dense Clustered Multi-Channel Wireless Sensor Cloud

    Directory of Open Access Journals (Sweden)

    Sivaramakrishnan Sivakumar

    2015-08-01

    Full Text Available Dense Wireless Sensor Network Clouds have an inherent issue of latency and packet drops with regards to data collection. Though there is extensive literature that tries to address these issues through either scheduling, channel contention or a combination of the two, the problem still largely exists. In this paper, a Clustered Multi-Channel Scheduling Protocol (CMSP is designed that creates a Voronoi partition of a dense network. Each partition is assigned a channel, and a scheduling scheme is adopted to collect data within the Voronoi partitions. This scheme collects data from the partitions concurrently and then passes it to the base station. CMSP is compared using simulation with other multi-channel protocols like Tree-based Multi-Channel, Multi-Channel MAC and Multi-frequency Media Access Control for wireless sensor networks. Results indicate CMSP has higher throughput and data delivery ratio at a lower power consumption due to network partitioning and hierarchical scheduling that minimizes load on the network.

  13. Intraluminal Radioactive Stent Compared with Covered Stent Alone for the Treatment of Malignant Esophageal Stricture

    International Nuclear Information System (INIS)

    Wang Zhongmin; Huang Xunbo; Cao Jun; Huang Gang; Chen Kemin; LIu Yu; Liu Fenju

    2012-01-01

    Objective: This study was designed to compare the clinical effectiveness of intraluminal radioactive stent loaded with iodine-125 seeds implantation versus covered stent alone insertion in patients with malignant esophageal stricture. Methods: We studied two groups of patients with malignant esophageal stricture. Group A comprised 28 patients (19 men and 9 women) who underwent intraluminal radioactive stent loaded with iodine-125 seeds implantation and were followed prospectively. Group B comprised 30 patients (18 men and 12 women) who had previously received covered stent alone insertion; these patients were evaluated retrospectively. There was no crossover between the two groups during follow-up. Informed consent was obtained from each patient, and our institutional review board approved the study. The dysphagia score, overall survival rates, complication rates, and reintervention rates were compared in the two groups. Results: There were no significant differences between the two groups in terms of baseline characteristics. Stent placement was technically successful and well tolerated in all patients. The dysphagia score was improved in both groups after stent placement. The median survival was significantly longer in group A than in group B: 11 versus 4.9 months, respectively (P < 0.001). The complications of chest pain, esophageal reflux, and stent migration was more frequent in group B, but this difference did not reach statistical significance. There was no statistical difference in reintervention between two groups. Conclusions: Intraluminal radioactive stent loaded with iodine-125 seeds implantation was a feasible and practical management in treating malignant esophageal stricture and was superior to covered stent alone insertion, as measured by survival.

  14. Glued versus stapled anastomosis of the colon: An experimental study to determine comparative resistance to intraluminal pressure

    Directory of Open Access Journals (Sweden)

    Jiri Paral

    2014-07-01

    Conclusion: Healing with absorbable synthetic glue was as good as with staples. Glued anastomoses resisted pressures that were statistically significantly higher than physiological intraluminal colon pressures but lower than stapled ones.

  15. Designing a Multichannel Map Service Concept

    Directory of Open Access Journals (Sweden)

    Hanna-Marika Halkosaari

    2013-01-01

    Full Text Available This paper introduces a user-centered design process for developing a multichannel map service. The aim of the service is to provide hikers with interactive maps through several channels. In a multichannel map service, the same spatial information is available through various channels, such as printed maps, Web maps, mobile maps, and other interactive media. When properly networked, the channels share a uniform identity so that the user experiences the different channels as a part of a single map service. The traditional methods of user-centered design, such as design probes, personas, and scenarios, proved useful even in the emerging field of developing multichannel map services. The findings emphasize the need to involve users and multidisciplinary teams in the conceptual phases of designing complex services aimed at serving various kinds of users.

  16. [The role of colonoscopy in early diagnosis of intraluminal recurrences in patients already treated for colorectal cancer].

    Science.gov (United States)

    Barillari, P; Manetti, G; Bovino, A; Puce, Y; Piovanello, P; Cioè, I; Sammartino, P; Stipa, V

    1996-11-01

    It is a common opinion that the more often and the more rigorously the colon is examined, the more lesions will be discovered and diagnosed. However it has not been shown which methods of colonic examination and which regimen of surveillance should be used. Chart review was conducted on 481 patients who underwent curative resection for colorectal cancer between 1980 and 1990. Colonoscopy was performed preoperatively, after 12-15 months from surgical treatment, and then at an interval of 12-24 months, or when symptoms appeared. About ten percent of patients developed intraluminal recurrences, and more than 25% adenomatous polyps. More than one half of the metachronous lesions arise within the first 24 months. The median time to diagnosis was 25 months for intraluminal recurrences and 22 months for adenomatous polyps. Patients with left sited tumor at an advanced stage run a higher risk of developing recurrent intraluminal disease, and patients who presented associated polyps at the time of the operation for the index cancer have a higher risk of developing new polyps. About 50% of recurrences were detected when patients were asymptomatic. Colonoscopy must be performed within the first 12-15 months after operation, while an interval of 24 months between each examination seems sufficient to guarantee an early detection of metachronous lesion. Asymptomatic patients are more frequently reoperated for cure and thus have a better survival rate.

  17. Evaluation of multichannel reproduced sound

    DEFF Research Database (Denmark)

    Choisel, Sylvain; Wickelmaier, Florian Maria

    2007-01-01

    A study was conducted with the goal of quantifying auditory attributes which underlie listener preference for multichannel reproduced sound. Short musical excerpts were presented in mono, stereo and several multichannel formats to a panel of forty selected listeners. Scaling of auditory attributes......, as well as overall preference, was based on consistency tests of binary paired-comparison judgments and on modeling the choice frequencies using probabilistic choice models. As a result, the preferences of non-expert listeners could be measured reliably at a ratio scale level. Principal components derived...

  18. Multi-channel data acquisition system for CT

    International Nuclear Information System (INIS)

    Cao Fuqiang; He Bin; Liu Guohua; Xu Minjian

    2009-01-01

    The architecture design and realization of a data acquisition system for multi-channel CT is described. The article introduces the conversion of analog signal to digital signal, the data cache and transmission. This data acquisition system can be widely used in the system which requires the multi-channel, weak current signal detection. (authors)

  19. Anesthetic and Airways Management of a Dog with Severe Tracheal Collapse during Intraluminal Stent Placement

    Directory of Open Access Journals (Sweden)

    M. Argano

    2013-01-01

    Full Text Available This case report describes the anesthetic and airways management of a dog affected by 4th degree tracheal collapse and undergoing endoscope-guided intraluminal stent placement. After premedication with acepromazine and butorphanol, general anesthesia was induced with propofol and maintained with intravenous propofol and butorphanol in constant rate infusion. During intraluminal stent placement, oxygen was supplemented by means of a simple and inexpensive handmade device, namely, a ureteral catheter inserted into the trachea and connected to an oxygen source, which allowed for the maintenance of airways’ patency and adequate patient’s oxygenation, without decreasing visibility in the surgical field or interfering with the procedure. The use of the technique described in the present paper was the main determinant of the successful anesthetic management and may be proposed for similar critical cases in which surgical manipulation of the tracheal lumen, which may potentially result in hypoxia by compromising airways patency, is required.

  20. Multichannel photocells for image converters with color separation

    Energy Technology Data Exchange (ETDEWEB)

    Denisova, E. A.; Uzdovskii, V. V., E-mail: uzdovskii@list.ru; Khainovskii, V. I. [Moscow Institute of Electronic Technology (Russian Federation)

    2011-12-15

    The results of a study of photoelectric processes in photosensitive structures based on a multichannel vertically integrated p-n junction are presented. Optical radiation absorption in the space-charge region of a multichannel vertically integrated structure is studied.

  1. Computer-based multi-channel analyzer based on internet

    International Nuclear Information System (INIS)

    Zhou Xinzhi; Ning Jiaoxian

    2001-01-01

    Combined the technology of Internet with computer-based multi-channel analyzer, a new kind of computer-based multi-channel analyzer system which is based on browser is presented. Its framework and principle as well as its implementation are discussed

  2. The portable micro-computerized multichannel spectrometer for geological application

    International Nuclear Information System (INIS)

    Fang Fang; Jia Wenyi; Zou Rongsheng; Ma Yingjie; Zhou Jianbin

    1999-01-01

    The portable micro-computerized multichannel spectrometer is based on the book computer and employs the A/D integrated circuit with 12 bits. It is a 2048 channel spectrometer which is consisted of hardware and software. The author analyzed the hardware circuit and software construction of the micro-computerized multichannel spectrometer which is suitable for filed geological application. The main technical specifications and application of the new multichannel spectrometer were also discussed

  3. The portable micro-computerized multichannel spectrometer for geological application

    International Nuclear Information System (INIS)

    Fang Fang; Jia Wenyi; Zhou Rongsheng; Ma Yingjie; Zhou Jianbin

    1999-01-01

    The portable micro-computerized multichannel spectrometer is based on the book computer and employs the A/D integrated circuit with 12 bits. It is a 2048 channel spectrometer which consists of hardware and software. The author analyzed the hardware circuit and software construction of the micro-computerized multichannel spectrometer which is suitable for field geological application. The main technical specifications and application of the new multichannel spectrometer were also discussed

  4. Development and implementation of own software for dosimetry multichannel film

    International Nuclear Information System (INIS)

    Jimenez Feltstrom, D.; Reyes Garcia, R.; Luis Simon, F. J.; Carrasco Herrera, M.; Sanchez Carmona, G.; Herrador Cordoba, M.

    2013-01-01

    The objective of this work is to develop its own software for multichannel film dosimetry Radiochromic EBT2. Compare the results obtained with its use in multichannel and single-channel dosimetry. Check that the multi-channel dosimetry eliminates much of the artifacts caused by dirt, fingerprints, scratches, etc. Radiochromic in film and scanner devices. (Author)

  5. Comparative analysis of intraluminal radiation stent in treatment of advanced esophageal carcinoma

    International Nuclear Information System (INIS)

    Guo Jinhe; Teng Gaojun; Zhu Guangyu; He Shicheng; Fang Wen; Deng Gang; Li Guozhao

    2007-01-01

    Objective: To compare the clinical effectiveness of intraluminal radiation stent with that of common covered stent to palliate dysphagia in advanced esophageal cancer. Methods: Fifty three cases were randomly assigned to the experimental group (Group A, n=27) and the control group (Group B, n26). Radiation stents were placed in Group A and common covered stents were placed in Group B. A randomized trial was performed to compare the two groups with respect to complications, relief of dysphagia, and overall survival period. Results: The placement of stents were successful in all the 53 patients. In Group A, no leakage of radiation source was observed through ECT examination, and no displacement of radiation seeds was found through radiography. The follow-up CT showed reduced lesion size compared to presurgical lesion. Three of the 5 patients who underwent uncovered radiation stent placement showed complete necrosis and inflammatory hyperblastosis in tumor tissue adjacent to radiation particles at 2 months follow-up. The lumen of the stents were smooth and had no overgrowth of tumor tissue. Granulation hyperplasia was found at both ends of the stents, prominent at the proximal ends, The incidence of stent- related complications had no significant difference between group A and group B (test, P>0.05). Dysphasia resolved significantly after stent placement in both groups. The improvement of dysphasia was more significant in Group A than in Group B after 2 months of stent placement (1.37±0.56 in group A, 1.82±0.50 in group B,P=0.004). The median survival period was longer in Group A than in Group B (7 months vs 4 months ). The mean survival period was also longer in Group A than in Group B (8.3 months vs 3.5 months). There was a statistically significant difference in the survival period between the two groups (P<0.01). Conclusion: Intraluminal radiation esophageal stent can not only palliate dysphagia but also restrain tumor growth. Palliation period of dysphagia and

  6. Effects of Intraluminal Irradiation with Holmium-166 for TIPS Stenosis: Experimental Study in a Swine Model

    Energy Technology Data Exchange (ETDEWEB)

    Park, Ji Seon; Oh, Joo Hyeong; Kim, Deog Yoon; Park, Yong Koo; Kim, Soo Joong [Kyung Hee University Medical Center, Seoul (Korea, Republic of); Park, Sang Joon [Kang Dong Sacred Heart Hospital, Hallym University, Seoul (Korea, Republic of)

    2007-04-15

    We wanted to evaluate the effectiveness of intraluminal irradiation with Holmium-166 ({sup 166}Ho) for reducing the pseudointimal hyperplasia (PIH) in the transjugular intrahepatic portosystemic shunt (TIPS) tract in a swine model. TIPS was performed in 12 domestic pigs, after the creation of portal hypertension by intraportal injection of a mixture of N-butyl-2- cyanoacrylate (NBCA) and lipiodol. Five pigs first underwent intraluminal irradiation (30 Gy) in the parenchymal tract with using a {sup 166}Ho solution-filled balloon catheter, and this was followed by the placement of a nitinol stent in the TIPS tract. For the seven control pigs, the balloon was filled with saline and contrast media mixture. Two weeks later, follow-up portography and histological analysis were performed. TIPS was successfully performed in all twelve pigs with achieving artificially induced portal hypertension. Portography performed two weeks after TIPS showed the patent tracts in the TIPS tracts that were irradiated with {sup 166}Ho (5/5, 100%), whereas either completely (5/6, 83.3%) or partially (1/6, 16.7%) occluded TIPS were seen in the seven pigs of the nonirradiated control group, except in one pig that experienced periprocedural death due to bleeding. Histological analysis showed a statistically significant difference for the maximal PIH (irradiated: 32.8%, nonirradiated: 76.0%, p < 0.001) between the two groups. Intraluminal irradiation with 30 Gy of {sup 166}Ho for TIPS significantly improved the TIPS patency in a swine model of portal hypertension during a 2- week period of follow-up.

  7. Positive intraluminal bowel contrast on computed tomography following oral ingestion of Kayexelate

    International Nuclear Information System (INIS)

    Zissin, R.; Stackievicz, R.; Osadchy, A.; Gayer, G.

    2008-01-01

    Our study presents the computed tomography (CT) manifestations of orally ingested kayexelate (a powdered form of sodium polystyrene sulphonate) used to treat hyperkalemia. Five patients with whom kayexelate appeared as high-attenuating intraluminal enteric content, similar to oral contrast material or leakage of intravascular contrast, are reported. Radiologists should be familiar with its appearance as it may mimic oral or vascular contrast within the gastrointestinal tract, a finding that may lead to a diagnostic error or misinterpretation. (author)

  8. Order fulfillment and logistics considerations for multichannel retailers

    NARCIS (Netherlands)

    Roodbergen, Kees Jan; Kolman, Inger B.; Zijm, W.H.M.; Klumpp, M.; Clausen, V.; Ten Hompel, M.

    2016-01-01

    This paper addresses the challenge of making multichannel decisions for order fulfillment and logistics. We present a framework for multichannel strategies consisting of seven elements. Some channel decisions are part of the marketing mix, with the ultimate choice left to the customer. Other channel

  9. Multichannel, sequential or combined X-ray spectrometry

    International Nuclear Information System (INIS)

    Florestan, J.

    1979-01-01

    X-ray spectrometer qualities and defects are evaluated for sequential and multichannel categories. Multichannel X-ray spectrometer has time-coherency advantage and its results could be more reproducible; on the other hand some spatial incoherency limits low percentage and traces applications, specially when backgrounds are very variable. In this last case, sequential X-ray spectrometer would find again great usefulness [fr

  10. Calculated characteristics of multichannel photoelectron multipliers

    International Nuclear Information System (INIS)

    Vasil'chenko, V.G.; Dajkovskij, A.G.; Milova, N.V.; Rakhmatov, V.E.; Rykalin, V.I.

    1990-01-01

    Structural features and main calculated characteristics of some modifications of position-sensitive two-coordinate multichannel photoelectron multipliers (PEM) with plate-type multiplying systems are described. The presented PEM structures are free from direct optical and ion feedbacks, provide coordinate resolution ≅ 1 mm with efficiency of photoelectron detection ≅ 90%. Capabilities for using silicon field-effect photocathodes, providing electron extraction into vacuum, as well as prospects of using multichannel multiplying systems for readout of the data from solid detectors are considered

  11. The Buywell Way: seven essential practices of a highly successful multi-channel e-tailer

    Directory of Open Access Journals (Sweden)

    Mary Tate

    2005-05-01

    Full Text Available After the dot-com bust there is considerable evidence that multi-channel retailers are more successful than purely on-line retailers. Multi-channel retailing is becoming mainstream and considerable research exists on successful multi-channel strategies. Despite this, some organisations are having more success than others with their multi-channel approach. We talked to the management of one of Australasia’s most successful multi-channel apparel and home-ware retailers about the theory and practice of multi-channel retailing, with the aim of building on existing theory in multi-channel e-commerce.

  12. Highly Efficient Compression Algorithms for Multichannel EEG.

    Science.gov (United States)

    Shaw, Laxmi; Rahman, Daleef; Routray, Aurobinda

    2018-05-01

    The difficulty associated with processing and understanding the high dimensionality of electroencephalogram (EEG) data requires developing efficient and robust compression algorithms. In this paper, different lossless compression techniques of single and multichannel EEG data, including Huffman coding, arithmetic coding, Markov predictor, linear predictor, context-based error modeling, multivariate autoregression (MVAR), and a low complexity bivariate model have been examined and their performances have been compared. Furthermore, a high compression algorithm named general MVAR and a modified context-based error modeling for multichannel EEG have been proposed. The resulting compression algorithm produces a higher relative compression ratio of 70.64% on average compared with the existing methods, and in some cases, it goes up to 83.06%. The proposed methods are designed to compress a large amount of multichannel EEG data efficiently so that the data storage and transmission bandwidth can be effectively used. These methods have been validated using several experimental multichannel EEG recordings of different subjects and publicly available standard databases. The satisfactory parametric measures of these methods, namely percent-root-mean square distortion, peak signal-to-noise ratio, root-mean-square error, and cross correlation, show their superiority over the state-of-the-art compression methods.

  13. Acid and non-acid reflux patterns in patients with erosive esophagitis and non-erosive reflux disease (NERD): a study using intraluminal impedance monitoring

    NARCIS (Netherlands)

    Conchillo, José M.; Schwartz, Matthijs P.; Selimah, Mohamed; Samsom, Melvin; Sifrim, Daniel; Smout, André J.

    2008-01-01

    BACKGROUND: Non-erosive reflux disease (NERD) and erosive esophagitis (EE) are the most common phenotypic presentations of gastroesophageal reflux disease (GERD). AIM: To assess acid and non-acid reflux patterns in patients with EE and NERD using combined esophageal pH-impedance monitoring. METHODS:

  14. Acid and non-acid reflux patterns in patients with erosive esophagitis and non-erosive reflux disease (NERD) : A study using intraluminal impedance monitoring

    NARCIS (Netherlands)

    Conchillo, Jose M.; Schwartz, Matthijs P.; Selimah, Mohamed; Samsom, Melvin; Sifrim, Daniel; Smout, Andre J.

    Background Non-erosive reflux disease (NERD) and erosive esophagitis (EE) are the most common phenotypic presentations of gastroesophageal reflux disease (GERD). Aim To assess acid and non-acid reflux patterns in patients with EE and NERD using combined esophageal pH-impedance monitoring. Methods A

  15. Multi-channel software defined radio experimental evaluation and analysis

    CSIR Research Space (South Africa)

    Van der Merwe, JR

    2014-09-01

    Full Text Available Multi-channel software-defined radios (SDRs) can be utilised as inexpensive prototyping platforms for transceiver arrays. The application for multi-channel prototyping is discussed and measured results of coherent channels for both receiver...

  16. Treatment of 9 cases of pulmonary atelectasis caused by endobronchial tuberculosis with intraluminal stent implantation

    International Nuclear Information System (INIS)

    Ji Hongjiang; Li Qiang; Liu Zhongling; Bai Chong; Yao Xiaopeng; Zhao Lijun; Xu Hao; Dong Yuchao; Huang Haidong; Wang Qin

    2007-01-01

    Objective: To evaluate the effect and safety of intraluminal stent implantation in the treatment of complete airway obstruction with unilateral pulmonary atelectasis caused by endobronchial tuberculosis (EBTB). Methods: 9 cases of pulmonary atelectasis caused by EBTB were treated with high- frequency electricity/microwave, balloon dilation and endobronchial stent implantation. At the time of 1 week and 4-6 months after stenting ,the diameters of stenotic segment were measured. Results: All 9 cases with atelectasis of EBTB showed complete re-expansion within 3 days after the stent implantation. The mean diameter of the stenotic segments of 9 EBTB patients increased to 9.17 ± 1.24 mm at 7th day after stent implantation; 3 of 9 EBTB patients occured mild restenosis after implantation of tracheobronchial stents. However, combination therapy of cryotherapy and balloon dilation can effectively prevent the aggravation of restenosis. Conclusion: Comparing with traditional surgical treatment, the intraluminal stent implantation for atelectasis caused by EBTB is a new, effective, safe and microtraumatic method with reliable preservation of pulmonary function. (authors)

  17. Multichannel compressive sensing MRI using noiselet encoding.

    Directory of Open Access Journals (Sweden)

    Kamlesh Pawar

    Full Text Available The incoherence between measurement and sparsifying transform matrices and the restricted isometry property (RIP of measurement matrix are two of the key factors in determining the performance of compressive sensing (CS. In CS-MRI, the randomly under-sampled Fourier matrix is used as the measurement matrix and the wavelet transform is usually used as sparsifying transform matrix. However, the incoherence between the randomly under-sampled Fourier matrix and the wavelet matrix is not optimal, which can deteriorate the performance of CS-MRI. Using the mathematical result that noiselets are maximally incoherent with wavelets, this paper introduces the noiselet unitary bases as the measurement matrix to improve the incoherence and RIP in CS-MRI. Based on an empirical RIP analysis that compares the multichannel noiselet and multichannel Fourier measurement matrices in CS-MRI, we propose a multichannel compressive sensing (MCS framework to take the advantage of multichannel data acquisition used in MRI scanners. Simulations are presented in the MCS framework to compare the performance of noiselet encoding reconstructions and Fourier encoding reconstructions at different acceleration factors. The comparisons indicate that multichannel noiselet measurement matrix has better RIP than that of its Fourier counterpart, and that noiselet encoded MCS-MRI outperforms Fourier encoded MCS-MRI in preserving image resolution and can achieve higher acceleration factors. To demonstrate the feasibility of the proposed noiselet encoding scheme, a pulse sequences with tailored spatially selective RF excitation pulses was designed and implemented on a 3T scanner to acquire the data in the noiselet domain from a phantom and a human brain. The results indicate that noislet encoding preserves image resolution better than Fouirer encoding.

  18. Clinical significance of intraluminal contrast enhancement in patients with spontaneous cervical artery dissection. A black-blood MRI study

    Energy Technology Data Exchange (ETDEWEB)

    Coppenrath, Eva; Lenz, Olga; Sommer, Nora; Treitl, Karla; Reiser, Maximilian [Munich Univ. (Germany). Inst. of Clinical Radiology; Lummel, Nina [Univ. Hospital Klinikum rechts der Isar Munich, Munich (Germany). Inst. of Neuroradiology and Interventional Neuroradiology; Linn, Jennifer [Univ. Hospital Dresden (Germany). Inst. of Neuroradiology; Bamberg, Fabian [Tuebingen Univ. (Germany). Diagnostical and Interventional Radiology; Pfefferkorn, Thomas [Munich Univ. (Germany). Interdisciplinary Stroke Center Munich; Saam, Tobias [Radiology Center Rosenheim (Germany)

    2017-07-15

    Recent studies have suggested that intraluminal thrombi show contrast enhancement on carotid black-blood T1w MRI. The aim of this study was to evaluate the significance of intraluminal contrast enhancement (iCE) regarding symptom status in patients with spontaneous cervical artery dissection (sCAD). 33 consecutive patients (19 men) with sCAD received a brain MRI (DIFF, T2w, T2{sup *}w, FLAIR) and a multi-sequence 3T-MRI with fat-saturated high-resolution black-blood T1w-sequences pre- and post-contrast, contrast-enhanced MR angiography and TOF images of carotid and vertebral arteries. Presence/absence of iCE, vessel occlusion and vessel wall hematoma (hyperintense in T1w pre-contrast) were analysed by two radiologists in consensus decision. 44 of 132 analysed vessels had a vessel wall hematoma, consistent with sCAD. In 17 of 44 dissected vessels an acute ischemic stroke was found. 16 of 17 (94.1 %) vessels ipsilateral to ischemic stroke demonstrated iCE, compared to 9 of 44 (20.4 %) dissected vessels without stroke (P< 0.001). The presence/absence of iCE resulted in a sensitivity, specificity, positive and negative predictive value and accuracy for ischemic stroke of 0.94, 0.67, 0.64, 0.95, and 0.77, respectively, and an odds ratio of 32.0. iCE, which is suggestive of intraluminal thrombus formation, is strongly correlated with ischemic symptoms in patients with sCAD.

  19. Clinical significance of intraluminal contrast enhancement in patients with spontaneous cervical artery dissection. A black-blood MRI study

    International Nuclear Information System (INIS)

    Coppenrath, Eva; Lenz, Olga; Sommer, Nora; Treitl, Karla; Reiser, Maximilian

    2017-01-01

    Recent studies have suggested that intraluminal thrombi show contrast enhancement on carotid black-blood T1w MRI. The aim of this study was to evaluate the significance of intraluminal contrast enhancement (iCE) regarding symptom status in patients with spontaneous cervical artery dissection (sCAD). 33 consecutive patients (19 men) with sCAD received a brain MRI (DIFF, T2w, T2"*w, FLAIR) and a multi-sequence 3T-MRI with fat-saturated high-resolution black-blood T1w-sequences pre- and post-contrast, contrast-enhanced MR angiography and TOF images of carotid and vertebral arteries. Presence/absence of iCE, vessel occlusion and vessel wall hematoma (hyperintense in T1w pre-contrast) were analysed by two radiologists in consensus decision. 44 of 132 analysed vessels had a vessel wall hematoma, consistent with sCAD. In 17 of 44 dissected vessels an acute ischemic stroke was found. 16 of 17 (94.1 %) vessels ipsilateral to ischemic stroke demonstrated iCE, compared to 9 of 44 (20.4 %) dissected vessels without stroke (P< 0.001). The presence/absence of iCE resulted in a sensitivity, specificity, positive and negative predictive value and accuracy for ischemic stroke of 0.94, 0.67, 0.64, 0.95, and 0.77, respectively, and an odds ratio of 32.0. iCE, which is suggestive of intraluminal thrombus formation, is strongly correlated with ischemic symptoms in patients with sCAD.

  20. Inhibition of early AAA formation by aortic intraluminal pentagalloyl glucose (PGG) infusion in a novel porcine AAA model.

    Science.gov (United States)

    Kloster, Brian O; Lund, Lars; Lindholt, Jes S

    2016-05-01

    The vast majority of abdominal aortic aneurysms found in screening programs are small, and as no effective treatment exits, many will expand until surgery is indicated. Therefore, it remains intriguing to develop a safe and low cost treatment of these small aneurysms, that is able to prevent or delay their expansion. In this study, we investigated whether intraluminal delivered pentagalloyl glucose (PGG) can impair the early AAA development in a porcine model. The infrarenal aorta was exposed in thirty pigs. Twenty underwent an elastase based AAA inducing procedure and ten of these received an additional intraluminal PGG infusion. The final 10 were sham operated and served as controls. All pigs who only had an elastase infusion developed macroscopically expanding AAAs. In pigs treated with an additional PGG infusion the growth rate of the AP-diameter rapidly returned to physiological values as seen in the control group. In the elastase group, histology revealed more or less complete resolution of the elastic lamellae in the media while they were more abundant, coherent and structurally organized in the PGG group. The control group displayed normal physiological growth and histology. In our model, intraluminal delivered PGG is able to penetrate the aortic wall from the inside and impair the early AAA development by stabilizing the elastic lamellae and preserving their integrity. The principle holds a high clinical potential if it can be translated to human conditions, since it, if so, potentially could represent a new drug for stabilizing small abdominal aneurysms.

  1. Acoustic impedances of ear canals measured by impedance tube

    DEFF Research Database (Denmark)

    Ciric, Dejan; Hammershøi, Dorte

    2007-01-01

    During hearing sensitivity tests, the sound field is commonly generated by an earphone placed on a subject ear. One of the factors that can affect the sound transmission in the ear is the acoustic impedance of the ear canal. Its importance is related to the contribution of other elements involved...... in the transmission such as the earphone impedance. In order to determine the acoustic impedances of human ear canals, the standardized method for measurement of complex impedances used for the measurement of the audiometric earphone impedances is applied. It is based on the transfer function between two microphone...... locations in an impedance tube. The end of the tube representing the measurement plane is placed at the ear canal entrance. Thus, the impedance seen from the entrance inward is measured on 25 subjects. Most subjects participated in the previous measurement of the ratio between the pressures at the open...

  2. Essays on Online and Multi-Channel Marketing

    OpenAIRE

    Zhang, Lingling

    2016-01-01

    Firms increasingly adopt online and multi-channel marketing strategies to reach and persuade consumers. Therefore, designing an effective marketing mix is critical to their success. The aim of my dissertation is to understand the strategy behind firms’ channel choices and assess marketing effectiveness. It consists of three large-scale empirical studies examining several important aspects of online and multi-channel marketing. My first essay focuses on the business-to-business (B2B) inte...

  3. Multichannel biomedical time series clustering via hierarchical probabilistic latent semantic analysis.

    Science.gov (United States)

    Wang, Jin; Sun, Xiangping; Nahavandi, Saeid; Kouzani, Abbas; Wu, Yuchuan; She, Mary

    2014-11-01

    Biomedical time series clustering that automatically groups a collection of time series according to their internal similarity is of importance for medical record management and inspection such as bio-signals archiving and retrieval. In this paper, a novel framework that automatically groups a set of unlabelled multichannel biomedical time series according to their internal structural similarity is proposed. Specifically, we treat a multichannel biomedical time series as a document and extract local segments from the time series as words. We extend a topic model, i.e., the Hierarchical probabilistic Latent Semantic Analysis (H-pLSA), which was originally developed for visual motion analysis to cluster a set of unlabelled multichannel time series. The H-pLSA models each channel of the multichannel time series using a local pLSA in the first layer. The topics learned in the local pLSA are then fed to a global pLSA in the second layer to discover the categories of multichannel time series. Experiments on a dataset extracted from multichannel Electrocardiography (ECG) signals demonstrate that the proposed method performs better than previous state-of-the-art approaches and is relatively robust to the variations of parameters including length of local segments and dictionary size. Although the experimental evaluation used the multichannel ECG signals in a biometric scenario, the proposed algorithm is a universal framework for multichannel biomedical time series clustering according to their structural similarity, which has many applications in biomedical time series management. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  4. Impact of concentration and rate of intraluminal drug delivery on absorption and gut wall metabolism of verapamil in humans.

    Science.gov (United States)

    Glaeser, Hartmut; Drescher, Siegfried; Hofmann, Ute; Heinkele, Georg; Somogyi, Andrew A; Eichelbaum, Michel; Fromm, Martin F

    2004-09-01

    In humans gut wall metabolism can be quantitatively as important as hepatic drug metabolism in limiting the systemic exposure to drugs after oral administration. However, it has been proposed that the role of gut wall metabolism might be overemphasized, because high luminal drug concentrations would lead to a saturation of gut wall metabolism. Therefore we investigated the impact of concentration and rate of intraluminal drug delivery on absorption (F(abs)) and gastrointestinal extraction (E(GI)) of a luminally administered cytochrome P450 (CYP) 3A4 substrate (verapamil) using a multilumen perfusion catheter in combination with a stable isotope technique. Two 20-cm-long, adjacent jejunal segments were isolated with the multilumen perfusion catheter in 7 subjects. In this study 80 mg of unlabeled verapamil (d0-verapamil 15 min) was infused into one segment over a 15-minute period, 80 mg of 3-fold deuterated verapamil (d3-verapamil 240 min) was administered over a 240-minute period into the other segment, and simultaneously, 5 mg of 7-fold deuterated verapamil (d7-verapamil) was injected intravenously over a 15-minute period. The rate of intraluminal drug delivery had only a modest effect on bioavailability of the verapamil isotopes (after correction for F abs ) (F/F abs d3-verapamil 240 min versus d0-verapamil 15 min, 0.24 +/- 0.10 versus 0.20 +/- 0.09; P d3-verapamil 240 min was 0.50 +/- 0.18 compared with 0.59 +/- 0.14 for d0 -verapamil 15 min ( P d0-verapamil 15 min ) correlated strongly with E GI (d3-verapamil 240 min ) (r = 0.94, P d0-verapamil 15 min /d3-verapamil 240 min (r = 0.62, P =.03). Substantial gut wall metabolism of verapamil occurs in humans and can be predicted from ex vivo data by use of shed enterocytes. The different intraluminal concentrations and rates of intraluminal drug delivery did not lead to a pronounced saturation of intestinal drug metabolism.

  5. The influence of the speed of food intake on multichannel impedance in patients with gastro-oesophageal reflux disease.

    Science.gov (United States)

    Bor, Serhat; Bayrakci, Berna; Erdogan, Askin; Yildirim, Esra; Vardar, Rukiye

    2013-10-01

    There is a general belief that gastro-oesophageal reflux increases after meals and especially following a rapid intake. To evaluate the impact of rapid vs. slow food intake on gastro-oesophageal reflux disease (GORD) patients. Forty-six GORD patients with heartburn and / or acid regurgitation once a week or more often common were included in this study. Participants were asked to eat the same standard meal within either 5 or 30 minutes under observation in a random order on 2 consecutive days. A total of 28 hours of recording were obtained by intraoesophageal impedance pH and number of liquid and mixed reflux episodes within 3 hours of the slow- and fast-eating postprandial periods were calculated. While all patients defined GORD symptoms, 10 (21.7%) had pathological 24-h intraoesophageal impedance measurement, 15 (32.6%) had pathological DeMeester and 21.7% had erosive oesophagitis. No difference has been shown according to the eating speed when all reflux episodes were taken together (754 vs. 733). Speed of food intake also did not have an impact on patients with normal vs. pathological 24-h intraoesophageal impedance or erosive vs. non-erosive. During the first postprandial hour, approximately half of the reflux events were non-acid, compared to 34.2% during the second hour and 26.8% during the third hour (p reflux episodes was significantly higher than non-acid reflux especially during the second and third hours and in total for 3 hours. This first study addressing the effect of eating speed on reflux episodes in GORD patients did not support the general belief that reflux increases following fast eating. Acid and non-acid reflux were similar at the first postprandial hour, then acid reflux episodes were predominantly higher, which implicate the importance of acid pockets.

  6. Multi-channel phase-equivalent transformation and supersymmetry

    OpenAIRE

    Shirokov, A. M.; Sidorenko, V. N.

    2000-01-01

    Phase-equivalent transformation of local interaction is generalized to the multi-channel case. Generally, the transformation does not change the number of the bound states in the system and their energies. However, with a special choice of the parameters, the transformation removes one of the bound states and is equivalent to the multi-channel supersymmetry transformation recently suggested by Sparenberg and Baye. Using the transformation, it is also possible to add a bound state to the discr...

  7. Mapping customer journeys in multichannel decision-making

    OpenAIRE

    Wolny, Julia; Charoensuksai, Nipawan

    2014-01-01

    This study is focused on multi-channel shopping, which refers to the integration of various channels in the consumer decision-making process. The term was coined in the early 2000s to signify the integration of offline and online shopping channels. It has since evolved to encompass the proliferating number of channels and media used to formulate, evaluate and execute buying decisions. With the explosion of mobile technologies and social media, multi-channel shopping has indeed become a journe...

  8. Multi-channel Kondo necklace

    International Nuclear Information System (INIS)

    Fazekas, P.; Kee Haeyoung.

    1993-06-01

    A multi-channel generalization of Doniach's Kondo necklace model is formulated, and its phase diagram studied in the mean-field approximation. Our intention is to introduce the possible simplest model which displays some of the features expected from the overscreened Kondo lattice. The N conduction electron channels are represented by N sets of pseudospins τ J , j = 1 1,..., N which are all antiferromagnetically coupled to a periodic array of modul S = 1/2 spins. Exploiting permutation symmetry in the channel index j allows us to write down the self-consistency equation for general N. For N > 2, we find that the critical temperature is rising with increasing Kondo interaction; we interpret this effect by pointing out that the Kondo coupling creates the composite pseudospin objects which undergo an ordering transition. The relevance of our findings to the underlying fermionic multi-channel problem is discussed. (author). 33 refs, 1 fig

  9. The importance of applicator design for intraluminal brachytherapy of rectal cancer

    International Nuclear Information System (INIS)

    Hansen, Johnny Witterseh; Jakobsen, Anders

    2006-01-01

    An important aspect of designing an applicator for radiation treatment of rectal cancer is the ability to minimize dose to the mucosa and noninvolved parts of the rectum wall. For this reason we investigated a construction of a flexible multichannel applicator with several channels placed along the periphery of a cylinder and a construction of a rigid cylinder with a central channel and interchangeable shields. Calculations of the dose gradient, dose homogeneity in the tumor, and shielding ability were performed for the two applicators in question. Furthermore, the influence on dose distribution around a flexible multichannel applicator from an unintended off-axis positioning of the source inside a bent channel was investigated by film measurements on a single bent catheter. Calculations showed that a single-channel applicator with interchangeable shields yields a higher degree of shielding and has a better dose homogeneity in the tumor volume than that of a multichannel applicator. A single-channel applicator with interchangeable shields was manufactured, and the influence of different size of shield angle on dose rate in front of and behind the shields was measured. While dose rate in front of the shield and shielding ability are closely independent of the size of the shield angle when measured 1 cm from the applicator surface, dose rate in more distant volumes will to some extent be influenced by shield angle due to volume scatter conditions

  10. Fast multichannel analyser

    Energy Technology Data Exchange (ETDEWEB)

    Berry, A; Przybylski, M M; Sumner, I [Science Research Council, Daresbury (UK). Daresbury Lab.

    1982-10-01

    A fast multichannel analyser (MCA) capable of sampling at a rate of 10/sup 7/ s/sup -1/ has been developed. The instrument is based on an 8 bit parallel encoding analogue to digital converter (ADC) reading into a fast histogramming random access memory (RAM) system, giving 256 channels of 64 k count capacity. The prototype unit is in CAMAC format.

  11. High dose rate afterloading intraluminal brachytherapy for advanced inoperable rectal carcinoma

    International Nuclear Information System (INIS)

    Hoskin, Peter J.; Canha, Sandra M. de; Bownes, Peter; Bryant, Linda; Jones, Rob Glynne

    2004-01-01

    Background and purpose: High dose rate intraluminal brachytherapy for tumours of the rectal and anal canal which were inoperable either because of the age and frailty of the patient or because of advanced disease has been evaluated. Patients and methods: In a retrospective review of 50 consecutive patients the two main indications for brachytherapy were as part of a radical radiation programme in those unfit for major surgery (26 patients) or as palliation for advanced or metastatic disease (22 patients). Radical treatment was either sole treatment delivering 6 Gy fraction 2 to 3 times weekly up to 36 Gy or as a boost of 12 Gy after 45 Gy in 25 fractions external beam chemoradiation. Palliative treatments were given predominantly as a single dose of 10 Gy. Results: This was predominantly a group of frail elderly patients with a median age of 82 years (range 35-91). Local tumour response was seen in 21/25 assessable patients with 14 complete responses. Median survival for the entire population was 6 months (range 1-54 months); in patients treated with 'radical' intent this was 25 months (range 1.5-54) and in the palliative group 7.2 months (range 1-37). The most common presenting symptom was bleeding per rectum for which a 64% response rate was obtained with 57% complete responses. Mucous discharge responded in 64% with 28% complete responses. The median duration of response was 7 months. Conclusion: Intraluminal HDR brachytherapy is an effective local treatment for patients otherwise unfit for radical surgery both as a component of radical treatment, or as a simple single palliative procedure

  12. A multi-channel microcomputer data acquisition system

    International Nuclear Information System (INIS)

    Loureiro, J.S.

    1987-01-01

    A data acquisition system was developed in order to transfer automatically to a 64 kb microcomputer the data generated by a nuclear spectroscopy system in a multichannel analyser. The data in the memory are stored in a floppy disk and will be further used as data entry for any spectrum analysis program, eliminating the tedious work of manually digitizing the spectrum and the possible mistakes associated with it. The developed system connected a POLYMAX 201 DP microcomputer, under CP/M operational system, to a NUCLEAR DATA MODEL ND-65 multichannel analyser and was planned for either local spectrum analysis in the microcomputer using a simplified program, or remote analysis in a mainframe using the sophisticated analysis program SAMPO. With the present system, the time spent between printing out of the 4096 channels with the multichannel analyser printer and its corresponding introduction in the analysis program has been reduced from about 6 hours to less than 2 minutes. (author)

  13. Tratamento cirúrgico em dois tempos do aneurisma toracoabdominal roto com prótese intraluminal sem sutura

    Directory of Open Access Journals (Sweden)

    Rodrigo de Castro BERNARDES

    1998-10-01

    Full Text Available O tratamento cirúrgico dos aneurismas toracoabominais exige toracofreno laparotomia, períodos prolongados de pinçamento aórtico com isquemia visceral, sangramento abundante de difícil controle, complicações pulmonares, renais, neurológicas e distúrbios de coagulação com morbimortalidade muitas vezes proibitiva para pacientes de idade avançada, ou portadores de distúrbios respiratórios, renais ou cardíacos prévios. A rotura aumenta em muito a já elevada taxa de morbimortalidade. Crawford (1-3 e Borst (4 descreveram operação em dois tempos para tratamento de aneurisma que atinge mais de um segmento da aorta, com bons resultados. O objetivo de nosso trabalho é mostrar a técnica cirúrgica em dois tempos, empregando prótese intraluminal sem sutura (5, 6. Esta técnica nos proporciona uma operação menos agressiva por abordar somente o segmento roto da aorta, portanto apenas uma cavidade é manipulada (tórax ou abdome. A anastomose com prótese intraluminal reduz em muito o tempo de pinçamento da aorta e, conseqüentemente, a isquemia visceral, diminuindo, também, o sangramento. A redução da agressividade cirúrgica sobre estes pacientes já gravemente enfermos nos proporcionou bons resultados cirúrgicos.The surgical management of thoracoabdominal aneurysms requires thoracophrenic laparotomy, prolonged periods of aortic clamping with visceral ischemia, profuse bleeding leading to a difficult postoperative course with pulmonary, renal, neurological complications, coagulation disturbances and others. All this resulting in an elevated morbidity/mortality very often contraindicating it for the very elderly or those with prior respiratory, renal or cardiac symptoms. Rupture of this aneurysm greatly increases the already high rate of morbidity/mortality. Crawford and Borst have described a two-stage surgery with good results, for aneurysms that affect more than one segment of aorta. The objective of our report is to demonstrate

  14. Multi-channel Kondo necklace

    Energy Technology Data Exchange (ETDEWEB)

    Fazekas, P; Haeyoung, Kee

    1993-06-01

    A multi-channel generalization of Doniach`s Kondo necklace model is formulated, and its phase diagram studied in the mean-field approximation. Our intention is to introduce the possible simplest model which displays some of the features expected from the overscreened Kondo lattice. The N conduction electron channels are represented by N sets of pseudospins {tau}{sub J}, j = 1 1,..., N which are all antiferromagnetically coupled to a periodic array of modul S = 1/2 spins. Exploiting permutation symmetry in the channel index j allows us to write down the self-consistency equation for general N. For N > 2, we find that the critical temperature is rising with increasing Kondo interaction; we interpret this effect by pointing out that the Kondo coupling creates the composite pseudospin objects which undergo an ordering transition. The relevance of our findings to the underlying fermionic multi-channel problem is discussed. (author). 33 refs, 1 fig.

  15. How to Succeed with Multichannel Management

    DEFF Research Database (Denmark)

    Madsen, Christian; Kræmmergaard, Pernille

    2016-01-01

    . This interplay between traditional and e-government channels remains to be explained. There is also a lack of empirical knowledge of how government organizations can apply findings from user studies and migrate citizens online while simultaneously reducing traffic through traditional channels. Therefore...... the authors present a detailed longitudinal case study of how public authorities collaborated to create a multichannel strategy for a mandatory online self-service application for single parents. After the strategy was carried out there was an increase in the use of the application and a substantial reduction...... in calls. The authors offer contributions to the channel choice literature and recommendations on multichannel management to practitioners....

  16. Determination of optimum "multi-channel surface wave method" field parameters.

    Science.gov (United States)

    2012-12-01

    Multi-channel surface wave methods (especially the multi-channel analyses of surface wave method; MASW) are routinely used to : determine the shear-wave velocity of the subsurface to depths of 100 feet for site classification purposes. Users are awar...

  17. Multichannel strategy - the dominant approach in modern retailing

    OpenAIRE

    Stojković Dragan; Lovreta Stipe; Bogetić Zoran

    2016-01-01

    The purpose of this paper is to thoroughly analyse the concept of multichannel strategy, focussing on retail, to enable the academic community and marketers to better understand its advantages and disadvantages. This paper presents a comprehensive literature review and financial data analysis. The authors have analysed the financial data of 88 retail companies in the 2007 to 2014 period, and have proven that the importance of multichannel strategy has grown...

  18. Multichannel quantum defect and reduced R-matrix

    International Nuclear Information System (INIS)

    Hategan, C.; Ionescu, R.A.; Cutoiu, D.; Gugiu, M.

    2002-01-01

    The collision of an electron with the atomic electronic core or the scattering of a nucleon on the atomic nucleus, usually, result into multiparticle excitations producing a resonance of a compound system, followed by its decay in reaction channels. Both in the electron-atom collisions and in nucleon-nucleus reactions, these multichannel resonances are described by poles of all R-Matrix elements. The resonances originating in single particle states, either in electron-atom collision or in nucleon-nucleus scattering, are approached in quite different descriptions. For example, the single-particle resonance in nuclear scattering is described, in R-Matrix Theory, by a perturbative method due to Bloch. The original single-nucleon state overlaps the actual states of the nucleus, resulting into a micro-giant description of the single particle resonance. The spectroscopic aspects of the single particle state, mixed with actual nuclear states, are subject of nucleon (or single particle) Strength Function. The electron, involving single particle Rydberg state in an atomic collision, 'avoids' its wave function mixing with that of inner multielectron core, because it is spatially far-away located from that core. This process is usually described by the Multichannel Quantum Defect Theory (MQDT). In the electron-atom scattering rather the effect of inner multielectron core on Rydberg electrons is studied by means of a global parameter, historically called 'Quantum Defect'. Both these types of resonances have in common the preserving of the single-particle wave function in a complex system with multiparticle excitations. In this work one approaches description of single-particle (electron or nucleon) resonance in a multichannel system. The single particle multichannel resonances are not longer described by a R-Matrix pole (specific for resonances originating in multiparticle excitations) but rather by a natural method for incorporating a single particle state in R-Matrix Theory

  19. Subject-specific optimization of channel currents for multichannel transcranial magnetic stimulation.

    Science.gov (United States)

    Cline, Christopher C; Johnson, Nessa N; He, Bin

    2015-01-01

    The goal of this work is to develop a focal transcranial magnetic stimulation (TMS) system using a multichannel coil array for high-resolution neuromodulation. We proposed a novel spatially-distributed stimulation strategy to significantly improve the focality of TMS. Computer simulations were conducted to evaluate the proposed approach and test the merits of multichannel TMS. Three different multichannel coil arrays were modeled in addition to a conventional figure-8 coil for comparison. Simulations were performed on finite element head models of six subjects constructed from anatomical MR images via an automated pipeline. Multichannel TMS arrays exhibited significantly more focal induced electric field magnitudes compared to the figure-8 coil. Additionally, electrical steering of stimulation sites without physical movement of the coil array was demonstrated.

  20. Acute intestinal injury induced by acetic acid and casein: prevention by intraluminal misoprostol

    International Nuclear Information System (INIS)

    Miller, M.J.; Zhang, x.J.; Gu, x.A.; Clark, D.A.

    1991-01-01

    Acute injury was established in anesthetized rabbits by intraluminal administration of acetic acid with and without bovine casein, into loops of distal small intestine. Damage was quantified after 45 minutes by the blood-to-lumen movement of 51 Cr-labeled ethylenediaminetetraacetic acid (EDTA) and fluorescein isothiocyanate-tagged bovine serum albumin as well as luminal fluid histamine levels. The amount of titratable acetic acid used to lower the pH of the treatment solutions to pH 4.0 was increased by the addition of calcium gluconate. Luminal acetic acid caused a 19-fold increase in 51 Cr-EDTA accumulation over saline controls; casein did not modify this effect. In saline controls, loop fluid histamine levels bordered on the limits of detection (1 ng/g) but were elevated 19-fold by acetic acid exposure and markedly increased (118-fold) by the combination of acid and casein. Intraluminal misoprostol (3 or 30 micrograms/mL), administered 30 minutes before acetic acid, significantly attenuated the increase in epithelial permeability (luminal 51 Cr-EDTA, fluorescein isothiocyanate-bovine serum albumin accumulation) and histamine release (P less than 0.05). Diphenhydramine, alone or in combination with cimetidine, and indomethacin (5 mg/kg IV) were not protective. It is concluded that exposure of the epithelium to acetic acid promotes the transepithelial movement of casein leading to enhanced mast cell activation and mucosal injury. Damage to the epithelial barrier can be prevented by misoprostol

  1. Acute intestinal injury induced by acetic acid and casein: prevention by intraluminal misoprostol

    Energy Technology Data Exchange (ETDEWEB)

    Miller, M.J.; Zhang, x.J.; Gu, x.A.; Clark, D.A. (Department of Pediatrics, Louisiana State University School of Medicine, New Orleans (USA))

    1991-07-01

    Acute injury was established in anesthetized rabbits by intraluminal administration of acetic acid with and without bovine casein, into loops of distal small intestine. Damage was quantified after 45 minutes by the blood-to-lumen movement of {sup 51}Cr-labeled ethylenediaminetetraacetic acid (EDTA) and fluorescein isothiocyanate-tagged bovine serum albumin as well as luminal fluid histamine levels. The amount of titratable acetic acid used to lower the pH of the treatment solutions to pH 4.0 was increased by the addition of calcium gluconate. Luminal acetic acid caused a 19-fold increase in {sup 51}Cr-EDTA accumulation over saline controls; casein did not modify this effect. In saline controls, loop fluid histamine levels bordered on the limits of detection (1 ng/g) but were elevated 19-fold by acetic acid exposure and markedly increased (118-fold) by the combination of acid and casein. Intraluminal misoprostol (3 or 30 micrograms/mL), administered 30 minutes before acetic acid, significantly attenuated the increase in epithelial permeability (luminal {sup 51}Cr-EDTA, fluorescein isothiocyanate-bovine serum albumin accumulation) and histamine release (P less than 0.05). Diphenhydramine, alone or in combination with cimetidine, and indomethacin (5 mg/kg IV) were not protective. It is concluded that exposure of the epithelium to acetic acid promotes the transepithelial movement of casein leading to enhanced mast cell activation and mucosal injury. Damage to the epithelial barrier can be prevented by misoprostol.

  2. Inhibition of light tunneling for multichannel excitations in longitudinally modulated waveguide arrays

    International Nuclear Information System (INIS)

    Lobanov, Valery E.; Vysloukh, Victor A.; Kartashov, Yaroslav V.

    2010-01-01

    We consider the evolution of multichannel excitations in longitudinally modulated waveguide arrays where the refractive index either oscillates out-of-phase in all neighboring waveguides or when it is modulated in phase in several central waveguides surrounded by out-of-phase oscillating neighbors. Both types of modulations allow resonant inhibition of light tunneling, but only the modulation of the latter type conserves the internal structure of multichannel excitations. We show that parameter regions where light tunneling inhibition is possible depend on the symmetry and structure of multichannel excitations. Antisymmetric multichannel excitations are more robust than their symmetric counterparts and experience nonlinearity-induced delocalization at higher amplitudes.

  3. Auralization of an orchestra using multichannel and multisource technique (A)

    DEFF Research Database (Denmark)

    Vigeant, Michelle C.; Wang, Lily M.; Rindel, Jens Holger

    2006-01-01

    Previous work has shown the importance of including source directivity in computer modeling for auralizations. A newer method to capture source directivity in auralizations is the multichannel technique, which uses multichannel anechoic recordings. In this study, five-channel anechoic recordings ...... made with a single channel orchestral anechoic recording using (ii) a surface source and (iii) a single omni-directional source. [Work supported by the National Science Foundation.]......Previous work has shown the importance of including source directivity in computer modeling for auralizations. A newer method to capture source directivity in auralizations is the multichannel technique, which uses multichannel anechoic recordings. In this study, five-channel anechoic recordings...... were obtained for every orchestral part of two symphonies at the Technical University of Denmark. Five-channel auralizations were then created for each instrument, located at its typical position on-stage in a concert hall, by convolving five impulse responses from sources that each represent...

  4. Value Creation Challenges in Multichannel Retail Business Models

    Directory of Open Access Journals (Sweden)

    Mika Yrjölä

    2014-08-01

    Full Text Available Purpose: The purpose of the paper is to identify and analyze the challenges of value creation in multichannel retail business models. Design/methodology/approach: With the help of semi-structured interviews with top executives from different retailing environments, this study introduces a model of value creation challenges in the context of multichannel retailing. The challenges are analyzed in terms of three retail business model elements, i.e., format, activities, and governance. Findings: Adopting a multichannel retail business model requires critical rethinking of the basic building blocks of value creation. First of all, as customers effortlessly move between multiple channels, multichannel formats can lead to a mismatch between customer and firm value. Secondly, retailers face pressures to use their activities to form integrated total offerings to customers. Thirdly, multiple channels might lead to organizational silos with conflicting goals. A careful orchestration of value creation is needed to determine the roles and incentives of the channel parties involved. Research limitations/implications: In contrast to previous business model literature, this study did not adopt a network-centric view. By embracing the boundary-spanning nature of the business model, other challenges and elements might have been discovered (e.g., challenges in managing relationships with suppliers. Practical implications: As a practical contribution, this paper has analyzed the challenges retailers face in adopting multichannel business models. Customer tendencies for showrooming behavior highlight the need for generating efficient lock-in strategies. Customized, personal offers and information are ways to increase customer value, differentiate from competition, and achieve lock-in. Originality/value: As a theoretical contribution, this paper empirically investigates value creation challenges in a specific context, lowering the level of abstraction in the mostly

  5. Intraluminal Palmaz stent implantation. First clinical case report on a balloon-expandable vessel prosthesis

    Energy Technology Data Exchange (ETDEWEB)

    Palmaz, J C; Richter, G M; Noeldge, G; Kauffmann, G W; Wenz, W

    1987-12-01

    A 74-year-old patient suffering from severe iliac artery stenosis and claudication was chosen to be the first candidate in the world to receive the Palmaz stent, a balloon-expandable intraluminal stent. This procedure was done in the Department of Radiology, University of Freiburg, FRG. The intervention and postprocedural course were uneventful. His walking distance improved from less than 100 m to unlimited walking capacity. The intra-arterial pressure gradient and ankle-arm pressure ratio also returned to normal.

  6. Use of trapezoidal shaping algorithm in the digital multi-channel system

    International Nuclear Information System (INIS)

    Wang Jihong; Wang Lianghou; Fang Zongliang

    2011-01-01

    It discusses one kind of digital filter technology-trapezoidal algorithm based on actual need of studying the digital multi-channel. Firstly, demonstrating the feasibility of the arithmetic with theoretical analysis; secondly, predigesting the process of the arithmetic; thirdly, simulating with MATLAB; lastly, using the arithmetic to measure data. The result of testing indicates trapezoidal shaping algorithm accords with the need of digital multi-channel shaping extraordinary. The best filter can be obtained by means of setting parameter due to superiority of digital multi-channel. (authors)

  7. Microfluidic Multichannel Flow Cytometer, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed innovation is a "Microfluidic Multichannel Flow Cytometer." Several novel concepts are integrated to produce the final design, which is compatible with...

  8. Selling to the multi-channel consumer : strategic and operational challenges for multi-channel retailers

    NARCIS (Netherlands)

    van Ameijden, D.; van Vulpen, J.; Huismans, J.; Wenting, R.; Krawczyk, A.; Weltevreden, J.W.J.; Krawczyk, A.C.

    2012-01-01

    Het ontwikkelen van een goede multichannel strategie is één van de belangrijkste uitdagingen waar retailers vandaag de dag voor staan. Een toenemend aantal ‘traditionele’ retailers ziet het opzetten van een webshop als een belangrijke aanvulling op hun fysieke winkels en probeert te profiteren van

  9. Influence of respiratory physiotherapy on gastro-oesophageal reflux in infants: A systematic review.

    Science.gov (United States)

    Van Ginderdeuren, Filip; Kerckhofs, Eric; Deneyer, Michel; Vanlaethem, Sylvie; Vandenplas, Yvan

    2015-09-01

    To provide a survey on the literature concerning the influence of respiratory physiotherapy on gastro-oesophageal reflux (GOR) in infants and young children. Electronic databases (Pubmed, Web of Science, PEDro) and reference lists of articles and narrative reviews were searched. Articles were included when infants and small children underwent oesophageal pH monitoring or pH-multichannel intraluminal impedance monitoring while respiratory physiotherapy was administered. Descriptive analysis was performed and two researchers scored the methodological quality of these studies. Out of 985 articles, seven (six English, one French) have been included, In total 277 patients were involved, 71 with cystic fibrosis. Depending on the technique used, four studies showed GOR to be aggravated during therapy, three studies reported no effect. The evidence is not conclusive on whether respiratory physiotherapy induces or aggravates GOR in infants and small children. Age, disease, and treatment options play an important role. More specific research, also focussing on the influence of respiratory physiotherapy on non-acid reflux and the impact of recently developed airway clearance techniques (ACT's) on GOR is necessary. © 2015 Wiley Periodicals, Inc.

  10. Association between Laryngeal Pepsin Levels and the Presence of Vocal Fold Polyps.

    Science.gov (United States)

    Wang, Lu; Tan, Jia-Jie; Wu, Ting; Zhang, Rui; Wu, Jia-Nuan; Zeng, Fang-Fang; Liu, You-Li; Han, Xiao-Yan; Li, Yan-Fei; Li, Xiang-Ping

    2017-01-01

    Objective To determine whether pepsin, the main component of refluxed gastric contents, is significantly associated with vocal fold polyps and to evaluate the diagnostic value of pepsin in vocal fold polyps' tissues. Study Design Cross-sectional study. Setting Nanfang Hospital of Southern Medical University. Subjects and Methods The study included 32 patients with vocal fold polyps and 16 healthy controls between 2011 and 2012. Reflux symptom index and reflux finding score assessments, 24-hour combined multichannel intraluminal impedance and pH monitoring, and biopsy of the vocal fold polyp tissues or posterior laryngeal mucosa (healthy controls) for immunohistochemical pepsin staining were performed. Results The expression of pepsin was significantly higher in patients with vocal fold polyps than in controls (28/32, 75% vs 5/16, 31.25%; P vocal fold polyps formation. In addition, pepsin immunohistochemical analysis of polyp biopsy samples appears to be a more sensitive and effective test for diagnosing laryngopharyngeal reflux than the reflux symptom index, the reflux finding score, and 24-hour pH monitoring in a clinical setting.

  11. Treatment of esophageal tumors using high intensity intraluminal ultrasound: first clinical results

    Directory of Open Access Journals (Sweden)

    Prat Frederic

    2008-06-01

    Full Text Available Abstract Background Esophageal tumors generally bear a poor prognosis. Radical surgery is generally the only curative method available but is not feasible in the majority of patients; palliative therapy with stent placement is generally performed. It has been demonstrated that High Intensity Ultrasound can induce rapid, complete and well-defined coagulation necrosis. Thus, for the treatment of esophageal tumors, we have designed an ultrasound applicator that uses an intraluminal approach to fill up this therapeutic gap. Methods Thermal ablation is performed with water-cooled ultrasound transducers operating at a frequency of 10 MHz. Single lesions extend from the transducer surface up to 10 mm in depth when applying an intensity of 14 W/cm2 for 10s. A lumen inside the therapy applicator provides path for an endoscopic ultrasound imaging probe operating at a frequency of 12 MHz. The mechanical rotation of the applicator around its axis enables treatment of sectorial or cylindrical volumes. This method is thus particularly suitable for esophageal tumors that may develop only on a portion of the esophageal circumference. Previous experiments were conducted from bench to in vivo studies on pig esophagi. Results Here we report clinical results obtained on four patients included in a pilot study. The treatment of esophageal tumors was performed under fluoroscopic guidance and ultrasound imaging. Objective tumor response was obtained in all cases and a complete necrosis of a tumor was obtained in one case. All patients recovered uneventfully and dysphagia improved significantly within 15 days, allowing for resuming a solid diet in three cases. Conclusion This clinical work demonstrated the efficacy of intraluminal high intensity ultrasound therapy for local tumor destruction in the esophagus.

  12. Multichannel analyzer embedded in FPGA; Analizador multicanal embebido en FPGA

    Energy Technology Data Exchange (ETDEWEB)

    Garcia D, A.; Hernandez D, V. M.; Vega C, H. R. [Universidad Autonoma de Zacatecas, Unidad Academica de Estudios Nucleares, Cipres No. 10, Fracc. La Penuela, 98060 Zacatecas, Zac. (Mexico); Ordaz G, O. O. [Universidad de Cordoba, Departamento de Arquitectura de Computadores, Electronica y Tecnologia Electronica, Campus de Rabanales, Ctra. N-IVa Km 396, 14071 Cordoba (Spain); Bravo M, I., E-mail: angelogarciad@hotmail.com [Universidad de Alcala de Henares, Departamento de Electronica, Campus Universitario, Carretera Madrid-Barcelona Km 33.600, 28801 Alcala de Henares, Madrid (Spain)

    2017-10-15

    Ionizing radiation has different applications, so it is a very significant and useful tool, which in turn can be dangerous for living beings if they are exposed to uncontrolled doses. However, due to its characteristics, it cannot be perceived by any of the senses of the human being, so that in order to know the presence of it, radiation detectors and additional devices are required to quantify and classify it. A multichannel analyzer is responsible for separating the different pulse heights that are generated in the detectors, in a certain number of channels; according to the number of bits of the analog to digital converter. The objective of the work was to design and implement a multichannel analyzer and its associated virtual instrument, for nuclear spectrometry. The components of the multichannel analyzer were created in VHDL hardware description language and packaged in the Xilinx Vivado design suite, making use of resources such as the ARM processing core that the System on Chip Zynq contains and the virtual instrument was developed on the LabView programming graphics platform. The first phase was to design the hardware architecture to be embedded in the FPGA and for the internal control of the multichannel analyzer the application was generated for the ARM processor in C language. For the second phase, the virtual instrument was developed for the management, control and visualization of the results. The data obtained as a result of the development of the system were observed graphically in a histogram showing the spectrum measured. The design of the multichannel analyzer embedded in FPGA was tested with two different radiation detection systems (hyper-pure germanium and scintillation) which allowed determining that the spectra obtained are similar in comparison with the commercial multichannel analyzers. (Author)

  13. Multi-Channel Deconvolution for Forward-Looking Phase Array Radar Imaging

    Directory of Open Access Journals (Sweden)

    Jie Xia

    2017-07-01

    Full Text Available The cross-range resolution of forward-looking phase array radar (PAR is limited by the effective antenna beamwidth since the azimuth echo is the convolution of antenna pattern and targets’ backscattering coefficients. Therefore, deconvolution algorithms are proposed to improve the imaging resolution under the limited antenna beamwidth. However, as a typical inverse problem, deconvolution is essentially a highly ill-posed problem which is sensitive to noise and cannot ensure a reliable and robust estimation. In this paper, multi-channel deconvolution is proposed for improving the performance of deconvolution, which intends to considerably alleviate the ill-posed problem of single-channel deconvolution. To depict the performance improvement obtained by multi-channel more effectively, evaluation parameters are generalized to characterize the angular spectrum of antenna pattern or singular value distribution of observation matrix, which are conducted to compare different deconvolution systems. Here we present two multi-channel deconvolution algorithms which improve upon the traditional deconvolution algorithms via combining with multi-channel technique. Extensive simulations and experimental results based on real data are presented to verify the effectiveness of the proposed imaging methods.

  14. Empirical Study on Multi-Channel Service Quality and Customer Loyalty of Retailers

    OpenAIRE

    Qi Yong-zhi

    2014-01-01

    This paper studies the influence of offline RSSQ (retailing store service quality), online store ESQ (E-service quality) and O2O MCISQ (multi-channel integration service quality) on traditional retailers' customer loyalty as well as the relation of them three in multi-channel retailing. 380 customers with both offline and online shopping experience at the same retailer's store are investigated. Through the structural equation model, we find out that in multi-channel retailing, RSSQ and MCISQ ...

  15. Numerical solution of the multichannel scattering problem

    International Nuclear Information System (INIS)

    Korobov, V.I.

    1992-01-01

    A numerical algorithm for solving the multichannel elastic and inelastic scattering problem is proposed. The starting point is the system of radial Schroedinger equations with linear boundary conditions imposed at some point R=R m placed somewhere in asymptotic region. It is discussed how the obtained linear equation can be splitted into a zero-order operator and its pertturbative part. It is shown that Lentini - Pereyra variable order finite-difference method appears to be very suitable for solving that kind of problems. The derived procedure is applied to dμ+t→tμ+d inelastic scattering in the framework of the adiabatic multichannel approach. 19 refs.; 1 fig.; 1 tab

  16. A fast multichannel analyser

    International Nuclear Information System (INIS)

    Berry, A.; Przybylski, M.M.; Sumner, I.

    1982-01-01

    A fast multichannel analyser (MCA) capable of sampling at a rate of 10 7 s -1 has been developed. The instrument is based on an 8 bit parallel encoding analogue to digital converter (ADC) reading into a fast histogramming random access memory (RAM) system, giving 256 channels of 64 k count capacity. The prototype unit is in CAMAC format. (orig.)

  17. Advances In Impedance Theory

    International Nuclear Information System (INIS)

    Stupakov, G.

    2009-01-01

    We review recent progress in the following areas of the impedance theory: calculation of impedance of tapers and small angle collimators; optical approximation and parabolic equation for the high-frequency impedance; impedance due to resistive inserts in a perfectly conducting pipe.

  18. Surveillance of colorectal cancer: effectiveness of early detection of intraluminal recurrences on prognosis and survival of patients treated for cure.

    Science.gov (United States)

    Barillari, P; Ramacciato, G; Manetti, G; Bovino, A; Sammartino, P; Stipa, V

    1996-04-01

    The authors evaluate the effectiveness of routine colonoscopy and marker evaluation in diagnosis of intraluminal recurrent cancer. Chart review was conducted on 481 patients who underwent curative resection for colorectal cancer between 1980 and 1990. Clinical visits were scheduled and carcinoembryonic antigen evaluation was performed every three months, and colonoscopy was performed preoperatively, 12 to 15 months after surgical treatment, and then with intervals of 12 to 24 months or when symptoms appeared. About 10 percent of patients developed intraluminal recurrences. More than one-half of metachronous lesions arose within the first 24 months, and median time to diagnosis was 25 months. Patients with left-sited tumors in the advanced stage had a higher risk of developing recurrent intraluminal disease. Twenty-nine patients underwent a second surgical operation, of which 17 cases were radical. In this group, the five-year survival was 70.6 percent, although no nonradically treated or nonresected patients survived longer than 31 months. Twenty-two patients were asymptomatic at time of diagnosis of recurrence, and of these, 12 patients underwent radical operation; on the other hand, of the 24 symptomatic patients, only 5 were treated radically. Carcinoembryonic antigen was the first sign of recurrence in eight cases. Colonoscopy must be performed within the first 12 to 15 months after operation, whereas an interval of 24 months between examinations seems sufficient to guarantee early detection of metachronous lesions. Serial tumor marker evaluation is of help in earlier diagnosis of local recurrences. Asymptomatic patients more frequently undergo another operation for cure and thus have a better survival rate.

  19. Acousto-Optic Applications for Multichannel Adaptive Optical Processor

    Science.gov (United States)

    1992-06-01

    AO cell and the two- channel line-scan camera system described in Subsection 4.1. The AO material for this IntraAction AOD-70 device was flint glass (n...Single-Channel 1.68 (flint glass ) 60,.0 AO Cell Multichannel 2.26 (TeO 2) 20.0 AO Cell Beam splitter 1.515 ( glass ) 50.8 Multichannel correlation was...Tone Intermodulation Dynamic Ranges of Longitudinal TeO2 Bragg Cells for Several Acoustic Power Densities 4-92 f f2 f 3 1 t SOURCE: Reference 21 TR-92

  20. Multichannel MAC Layer In Mobile Ad—Hoc Network

    Science.gov (United States)

    Logesh, K.; Rao, Samba Siva

    2010-11-01

    This paper we presented the design objectives and technical challenges in Multichannel MAC protocols in Mobile Ad-hoc Network. In IEEE 802.11 a/b/g standards allow use of multiple channels, only a single channel is popularly used, due to the lack of efficient protocols that enable use of Multiple Channels. Even though complex environments in ad hoc networks require a combined control of physical (PHY) and medium access control (MAC) layers resources in order to optimize performance. And also we discuss the characteristics of cross-layer frame and give a multichannel MAC approach.

  1. The Time Division Multi-Channel Communication Model and the Correlative Protocol Based on Quantum Time Division Multi-Channel Communication

    International Nuclear Information System (INIS)

    Liu Xiao-Hui; Pei Chang-Xing; Nie Min

    2010-01-01

    Based on the classical time division multi-channel communication theory, we present a scheme of quantum time-division multi-channel communication (QTDMC). Moreover, the model of quantum time division switch (QTDS) and correlative protocol of QTDMC are proposed. The quantum bit error rate (QBER) is analyzed and the QBER simulation test is performed. The scheme shows that the QTDS can carry out multi-user communication through quantum channel, the QBER can also reach the reliability requirement of communication, and the protocol of QTDMC has high practicability and transplantable. The scheme of QTDS may play an important role in the establishment of quantum communication in a large scale in the future. (general)

  2. Improving Pulse Rate Measurements during Random Motion Using a Wearable Multichannel Reflectance Photoplethysmograph

    Directory of Open Access Journals (Sweden)

    Kristen M. Warren

    2016-03-01

    Full Text Available Photoplethysmographic (PPG waveforms are used to acquire pulse rate (PR measurements from pulsatile arterial blood volume. PPG waveforms are highly susceptible to motion artifacts (MA, limiting the implementation of PR measurements in mobile physiological monitoring devices. Previous studies have shown that multichannel photoplethysmograms can successfully acquire diverse signal information during simple, repetitive motion, leading to differences in motion tolerance across channels. In this paper, we investigate the performance of a custom-built multichannel forehead-mounted photoplethysmographic sensor under a variety of intense motion artifacts. We introduce an advanced multichannel template-matching algorithm that chooses the channel with the least motion artifact to calculate PR for each time instant. We show that for a wide variety of random motion, channels respond differently to motion artifacts, and the multichannel estimate outperforms single-channel estimates in terms of motion tolerance, signal quality, and PR errors. We have acquired 31 data sets consisting of PPG waveforms corrupted by random motion and show that the accuracy of PR measurements achieved was increased by up to 2.7 bpm when the multichannel-switching algorithm was compared to individual channels. The percentage of PR measurements with error ≤ 5 bpm during motion increased by 18.9% when the multichannel switching algorithm was compared to the mean PR from all channels. Moreover, our algorithm enables automatic selection of the best signal fidelity channel at each time point among the multichannel PPG data.

  3. A multichannel analyzer computer system for simultaneously measuring 64 spectra

    International Nuclear Information System (INIS)

    Jin Yuheng; Wan Yuqing; Zhang Jiahong; Li Li; Chen Guozhu

    2000-01-01

    The author introduces a multichannel analyzer computer system for simultaneously measuring 64 spectra with 64 coded independent inputs. The system is developed for a double chopper neutron scattering time-of-flight spectrometer. The system structure, coding method, operating principle and performances are presented. The system can also be used for other nuclear physics experiments which need multichannel analyzer with independent coded inputs

  4. Robust adaptive multichannel SAR processing based on covariance matrix reconstruction

    Science.gov (United States)

    Tan, Zhen-ya; He, Feng

    2018-04-01

    With the combination of digital beamforming (DBF) processing, multichannel synthetic aperture radar(SAR) systems in azimuth promise well in high-resolution and wide-swath imaging, whereas conventional processing methods don't take the nonuniformity of scattering coefficient into consideration. This paper brings up a robust adaptive Multichannel SAR processing method which utilizes the Capon spatial spectrum estimator to obtain the spatial spectrum distribution over all ambiguous directions first, and then the interference-plus-noise covariance Matrix is reconstructed based on definition to acquire the Multichannel SAR processing filter. The performance of processing under nonuniform scattering coefficient is promoted by this novel method and it is robust again array errors. The experiments with real measured data demonstrate the effectiveness and robustness of the proposed method.

  5. String-like lumen in below-the-knee chronic total occlusions on contrast-enhanced magnetic resonance angiography predicts intraluminal recanalization and better blood flow restoration

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Yue-Qi; Lu, Hai-Tao; Wei, Li-Ming; Cheng, Ying-Sheng; Wang, Jian-Bo; Zhao, Jun-Gong [Shanghai Jiao Tong University Affiliated Sixth People' s Hospital, Department of Diagnostic and Interventional Radiology, Shanghai (China); Liu, Fang [Shanghai Jiao Tong University Affiliated Sixth People' s Hospital, Department of Endocrinology, Shanghai (China)

    2017-07-15

    To determine whether string-like lumina (SLs) on contrast-enhanced magnetic resonance angiography (CE-MRA) predict better outcomes in diabetic patients with below-the-knee (BTK) chronic total occlusions (CTOs). This study involved 317 long-segment (>5 cm) BTK CTOs of 245 patients that were examined using CE-MRA and treated using endovascular angioplasty. An SL with a CTO was slowly filled with blood on conventional CE-MRA. Univariate and multivariate analyses were performed to identify predictors of procedural success, recanalisation method and immediate blood flow restoration. The target-lesion patency and limb-salvage rates were assessed. SL-positive CTOs (n = 60) achieved a higher technique success rate, preferred intraluminal angioplasty and better blood flow restoration than SL-negative CTOs (n = 257, P < 0.05). Multivariate analyses revealed that lesion length was the independent predictor of procedural success (P = 0.028). SL was a predictor of intraluminal angioplasty (P < 0.001) and good blood-flow restoration (P = 0.004). Kaplan-Meier analyses at 12 months revealed a higher target lesion patency rate (P = 0.04) and limb-salvage rate (P = 0.35) in SL-positive CTOs. In patients with BTK CTOs, SL predicted intraluminal angioplasty and good blood-flow restoration for BTK CTOs. (orig.)

  6. Separable expansion for realistic multichannel scattering problems

    International Nuclear Information System (INIS)

    Canton, L.; Cattapan, G.; Pisent, G.

    1987-01-01

    A new approach to the multichannel scattering problem with realistic local or nonlocal interactions is developed. By employing the negative-energy solutions of uncoupled Sturmian eigenvalue problems referring to simple auxiliary potentials, the coupling interactions appearing to the original multichannel problem are approximated by finite-rank potentials. By resorting to integral-equation tecniques the coupled-channel equations are then reduced to linear algebraic equations which can be straightforwardly solved. Compact algebraic expressions for the relevant scattering matrix elements are thus obtained. The convergence of the method is tasted in the single-channel case with realistic optical potentials. Excellent agreement is obtained with a few terms in the separable expansion for both real and absorptive interactions

  7. Multichannel photonic Hilbert transformers based on complex modulated integrated Bragg gratings.

    Science.gov (United States)

    Cheng, Rui; Chrostowski, Lukas

    2018-03-01

    Multichannel photonic Hilbert transformers (MPHTs) are reported. The devices are based on single compact spiral integrated Bragg gratings on silicon with coupling coefficients precisely modulated by the phase of each grating period. MPHTs with up to nine wavelength channels and a single-channel bandwidth of up to ∼625  GHz are achieved. The potential of the devices for multichannel single-sideband signal generation is suggested. The work offers a new possibility of utilizing wavelength as an extra degree of freedom in designing radio-frequency photonic signal processors. Such multichannel processors are expected to possess improved capacities and a potential to greatly benefit current widespread wavelength division multiplexed systems.

  8. Fast multichannel scaler

    International Nuclear Information System (INIS)

    Okayasu, T.; Takeuchi, S.; Nagai, S.

    1987-01-01

    A fast multichannel scaler achieving the minimum dwell time of 50 ns is described. The dead time due to memory cycle is eliminated by 4-phase operation of parallel-4 groups of counter RAMs. The MCS has 4 k channels in total. Differential nonlinearity is less than 0.4%. If an input pulse arrives near the channel boundary, it is caught temporarily for both channels and then sorted to go into a proper channel. Thus, the dead time near the channel boundary is also eliminated

  9. Modeling high dimensional multichannel brain signals

    KAUST Repository

    Hu, Lechuan

    2017-03-27

    In this paper, our goal is to model functional and effective (directional) connectivity in network of multichannel brain physiological signals (e.g., electroencephalograms, local field potentials). The primary challenges here are twofold: first, there are major statistical and computational difficulties for modeling and analyzing high dimensional multichannel brain signals; second, there is no set of universally-agreed measures for characterizing connectivity. To model multichannel brain signals, our approach is to fit a vector autoregressive (VAR) model with sufficiently high order so that complex lead-lag temporal dynamics between the channels can be accurately characterized. However, such a model contains a large number of parameters. Thus, we will estimate the high dimensional VAR parameter space by our proposed hybrid LASSLE method (LASSO+LSE) which is imposes regularization on the first step (to control for sparsity) and constrained least squares estimation on the second step (to improve bias and mean-squared error of the estimator). Then to characterize connectivity between channels in a brain network, we will use various measures but put an emphasis on partial directed coherence (PDC) in order to capture directional connectivity between channels. PDC is a directed frequency-specific measure that explains the extent to which the present oscillatory activity in a sender channel influences the future oscillatory activity in a specific receiver channel relative all possible receivers in the network. Using the proposed modeling approach, we have achieved some insights on learning in a rat engaged in a non-spatial memory task.

  10. Modeling high dimensional multichannel brain signals

    KAUST Repository

    Hu, Lechuan; Fortin, Norbert; Ombao, Hernando

    2017-01-01

    In this paper, our goal is to model functional and effective (directional) connectivity in network of multichannel brain physiological signals (e.g., electroencephalograms, local field potentials). The primary challenges here are twofold: first, there are major statistical and computational difficulties for modeling and analyzing high dimensional multichannel brain signals; second, there is no set of universally-agreed measures for characterizing connectivity. To model multichannel brain signals, our approach is to fit a vector autoregressive (VAR) model with sufficiently high order so that complex lead-lag temporal dynamics between the channels can be accurately characterized. However, such a model contains a large number of parameters. Thus, we will estimate the high dimensional VAR parameter space by our proposed hybrid LASSLE method (LASSO+LSE) which is imposes regularization on the first step (to control for sparsity) and constrained least squares estimation on the second step (to improve bias and mean-squared error of the estimator). Then to characterize connectivity between channels in a brain network, we will use various measures but put an emphasis on partial directed coherence (PDC) in order to capture directional connectivity between channels. PDC is a directed frequency-specific measure that explains the extent to which the present oscillatory activity in a sender channel influences the future oscillatory activity in a specific receiver channel relative all possible receivers in the network. Using the proposed modeling approach, we have achieved some insights on learning in a rat engaged in a non-spatial memory task.

  11. Modeling High-Dimensional Multichannel Brain Signals

    KAUST Repository

    Hu, Lechuan

    2017-12-12

    Our goal is to model and measure functional and effective (directional) connectivity in multichannel brain physiological signals (e.g., electroencephalograms, local field potentials). The difficulties from analyzing these data mainly come from two aspects: first, there are major statistical and computational challenges for modeling and analyzing high-dimensional multichannel brain signals; second, there is no set of universally agreed measures for characterizing connectivity. To model multichannel brain signals, our approach is to fit a vector autoregressive (VAR) model with potentially high lag order so that complex lead-lag temporal dynamics between the channels can be captured. Estimates of the VAR model will be obtained by our proposed hybrid LASSLE (LASSO + LSE) method which combines regularization (to control for sparsity) and least squares estimation (to improve bias and mean-squared error). Then we employ some measures of connectivity but put an emphasis on partial directed coherence (PDC) which can capture the directional connectivity between channels. PDC is a frequency-specific measure that explains the extent to which the present oscillatory activity in a sender channel influences the future oscillatory activity in a specific receiver channel relative to all possible receivers in the network. The proposed modeling approach provided key insights into potential functional relationships among simultaneously recorded sites during performance of a complex memory task. Specifically, this novel method was successful in quantifying patterns of effective connectivity across electrode locations, and in capturing how these patterns varied across trial epochs and trial types.

  12. Multi-channel imaging cytometry with a single detector

    Science.gov (United States)

    Locknar, Sarah; Barton, John; Entwistle, Mark; Carver, Gary; Johnson, Robert

    2018-02-01

    Multi-channel microscopy and multi-channel flow cytometry generate high bit data streams. Multiple channels (both spectral and spatial) are important in diagnosing diseased tissue and identifying individual cells. Omega Optical has developed techniques for mapping multiple channels into the time domain for detection by a single high gain, high bandwidth detector. This approach is based on pulsed laser excitation and a serial array of optical fibers coated with spectral reflectors such that up to 15 wavelength bins are sequentially detected by a single-element detector within 2.5 μs. Our multichannel microscopy system uses firmware running on dedicated DSP and FPGA chips to synchronize the laser, scanning mirrors, and sampling clock. The signals are digitized by an NI board into 14 bits at 60MHz - allowing for 232 by 174 pixel fields in up to 15 channels with 10x over sampling. Our multi-channel imaging cytometry design adds channels for forward scattering and back scattering to the fluorescence spectral channels. All channels are detected within the 2.5 μs - which is compatible with fast cytometry. Going forward, we plan to digitize at 16 bits with an A-toD chip attached to a custom board. Processing these digital signals in custom firmware would allow an on-board graphics processing unit to display imaging flow cytometry data over configurable scanning line lengths. The scatter channels can be used to trigger data buffering when a cell is present in the beam. This approach enables a low cost mechanically robust imaging cytometer.

  13. Nonsynchronous Noncommensurate Impedance Transformers

    DEFF Research Database (Denmark)

    Zhurbenko, Vitaliy; Kim, K

    2012-01-01

    Nonsynchronous noncommensurate impedance transformers consist of a combination of two types of transmission lines: transmission lines with a characteristic impedance equal to the impedance of the source, and transmission lines with a characteristic impedance equal to the load. The practical...... advantage of such transformers is that they can be constructed using sections of transmission lines with a limited variety of characteristic impedances. These transformers also provide comparatively compact size in applications where a wide transformation ratio is required. This paper presents the data...... matrix approach and experimentally verified by synthesizing a 12-section nonsynchronous noncommensurate impedance transformer. The measured characteristics of the transformer are compared to the characteristics of a conventional tapered line transformer....

  14. Multichannel scaler with fast channel advance

    International Nuclear Information System (INIS)

    Murphy, D.M.

    1985-01-01

    A multichannel scaler has been constructed which is capable of running as fast as 250 ns per channel. It is compact, low power and requires no special construction techniques. Readout is into a memory accessible by a microprocessor. (orig.)

  15. A wireless multi-channel recording system for freely behaving mice and rats.

    Science.gov (United States)

    Fan, David; Rich, Dylan; Holtzman, Tahl; Ruther, Patrick; Dalley, Jeffrey W; Lopez, Alberto; Rossi, Mark A; Barter, Joseph W; Salas-Meza, Daniel; Herwik, Stanislav; Holzhammer, Tobias; Morizio, James; Yin, Henry H

    2011-01-01

    To understand the neural basis of behavior, it is necessary to record brain activity in freely moving animals. Advances in implantable multi-electrode array technology have enabled researchers to record the activity of neuronal ensembles from multiple brain regions. The full potential of this approach is currently limited by reliance on cable tethers, with bundles of wires connecting the implanted electrodes to the data acquisition system while impeding the natural behavior of the animal. To overcome these limitations, here we introduce a multi-channel wireless headstage system designed for small animals such as rats and mice. A variety of single unit and local field potential signals were recorded from the dorsal striatum and substantia nigra in mice and the ventral striatum and prefrontal cortex simultaneously in rats. This wireless system could be interfaced with commercially available data acquisition systems, and the signals obtained were comparable in quality to those acquired using cable tethers. On account of its small size, light weight, and rechargeable battery, this wireless headstage system is suitable for studying the neural basis of natural behavior, eliminating the need for wires, commutators, and other limitations associated with traditional tethered recording systems.

  16. A wireless multi-channel recording system for freely behaving mice and rats.

    Directory of Open Access Journals (Sweden)

    David Fan

    Full Text Available To understand the neural basis of behavior, it is necessary to record brain activity in freely moving animals. Advances in implantable multi-electrode array technology have enabled researchers to record the activity of neuronal ensembles from multiple brain regions. The full potential of this approach is currently limited by reliance on cable tethers, with bundles of wires connecting the implanted electrodes to the data acquisition system while impeding the natural behavior of the animal. To overcome these limitations, here we introduce a multi-channel wireless headstage system designed for small animals such as rats and mice. A variety of single unit and local field potential signals were recorded from the dorsal striatum and substantia nigra in mice and the ventral striatum and prefrontal cortex simultaneously in rats. This wireless system could be interfaced with commercially available data acquisition systems, and the signals obtained were comparable in quality to those acquired using cable tethers. On account of its small size, light weight, and rechargeable battery, this wireless headstage system is suitable for studying the neural basis of natural behavior, eliminating the need for wires, commutators, and other limitations associated with traditional tethered recording systems.

  17. Multichannel shopper segments and their covariates

    NARCIS (Netherlands)

    Konus, U.; Verhoef, P.C.; Neslin, S.A.

    2008-01-01

    The proliferation of channels has created new challenges for research, including understanding how consumers may be segmented with respect to their information search and purchase behavior in multichannel environment. This research considers shopping a dynamic process that consists of search and

  18. Multichannel Shopper Segments and Their Covariates

    NARCIS (Netherlands)

    Konus, Umut; Verhoef, Peter C.; Neslin, Scott A.

    2008-01-01

    The proliferation of channels has created new challenges for research, including understanding how consumers may be segmented with respect to their information search and purchase behavior in multichannel environment. This research considers shopping a dynamic process that consists of search and

  19. Nylon filament coated with paraffin for intraluminal permanent middle cerebral artery occlusion in rats.

    Science.gov (United States)

    Zuo, Xia-Lin; Wu, Ping; Ji, Ai-Min

    2012-06-21

    A variety of intraluminal nylon filament has been used in rat middle cerebral artery occlusion (MCAO) models. However the lesion extent and its reproducibility vary among laboratories. The properties of nylon filament play a part of reasons for these variations. In the present study, we used paraffin-coated nylon filament for rat MCAO model, tested the effects and advanced improvement for making the rat MCAO. Forty male Sprague-Dawley (SD) rats were randomized into two groups, MCAO with traditional uncoated nylon filament (uMCAO) and MCAO with paraffin-coated nylon filament (cMCAO), three rats as normal group and sham group respectively. Assessment included mortality rates, model success rates, neurological deficit evaluation, and infarct volume. The study showed two rats died in uMCAO group, no rat died in cMCAO group within the 12h. The model success rate of uMCAO was 100%, while the uMCAO group was 55% (n=20, two died within 12h, seven rats were excluded as the brain slices showed no TTC staining due to subarachanoid hemorrhage). Neurological evaluation demonstrated group cMCAO had more worse neurological outcomes than group uMCAO, and the difference was statistically signification (pparaffin-coated nylon filament intraluminal occlusion provide better occlusion of middle cerebral artery than the uncoated nylon filament, improve the consistent of model, and raise the success rate to reduce the number of experimental animals. These positive results are much encouraging and interesting. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  20. Multichannel blind iterative image restoration

    Czech Academy of Sciences Publication Activity Database

    Šroubek, Filip; Flusser, Jan

    2003-01-01

    Roč. 12, č. 9 (2003), s. 1094-1106 ISSN 1057-7149 R&D Projects: GA ČR GA102/00/1711 Institutional research plan: CEZ:AV0Z1075907 Keywords : conjugate gradient * half-quadratic regularization * multichannel blind deconvolution Subject RIV: BD - Theory of Information Impact factor: 2.642, year: 2003 http://library.utia.cas.cz/prace/20030104.pdf

  1. Quasibound states at thresholds in multichannel impurity scattering

    International Nuclear Information System (INIS)

    Kim, Sang Wook; Park, Hwa-Kyun; Sim, H-S; Schomerus, Henning

    2003-01-01

    We investigate the threshold behaviour of transmission resonances and quasibound states in the multichannel scattering problems of a one-dimensional (1D) time-dependent impurity potential, and the related problem of a single impurity in a quasi-1D wire. It was claimed before in the literature that a quasibound state disappears when a transmission zero collides with the subband boundary. However, the transmission line shape, the Friedel sum rule, and the delay time show that the quasibound states still survive and affect the physical quantities. We discuss the relation between threshold behaviour of transmission resonances, and quasibound states and their boundary conditions in the general context of multichannel scatterings

  2. Compensating for evanescent modes and estimating characteristic impedance in waveguide acoustic impedance measurements

    DEFF Research Database (Denmark)

    Nørgaard, Kren Rahbek; Fernandez Grande, Efren

    2017-01-01

    The ear-canal acoustic impedance and reflectance are useful for assessing conductive hearing disorders and calibrating stimulus levels in situ. However, such probe-based measurements are affected by errors due to the presence of evanescent modes and incorrect estimates or assumptions regarding...... characteristic impedance. This paper proposes a method to compensate for evanescent modes in measurements of acoustic impedance, reflectance, and sound pressure in waveguides, as well as estimating the characteristic impedance immediately in front of the probe. This is achieved by adjusting the characteristic...... impedance and subtracting an acoustic inertance from the measured impedance such that the non-causality in the reflectance is minimized in the frequency domain using the Hilbert transform. The method is thus capable of estimating plane-wave quantities of the sought-for parameters by supplying only...

  3. Retrograde transdorsal-to-plantar or transplantar-to-dorsal intraluminal re-entry treatment following unsuccessful subintimal angioplasty for below-the-ankle arterial occlusion

    International Nuclear Information System (INIS)

    Zhu Yueqi; Zhao Jungong; Li Minghua; Tan Huaqiao; Wang Jianbo; Liu Fang; Cheng Yingsheng; Wang Jue; Cheng Yongde

    2011-01-01

    Objective: To assess the technical feasibility and efficacy of transdorsal-to-plantar (TDP) or transplantar-to-dorsal (TPD) intraluminal re-entry procedure following unsuccessful subintimal angioplasty for the treatment of arterial occlusion below the ankle. Methods: TDP or TPD retrograde intraluminal re-entry angioplasty was carried out in 8 diseased limbs of 8 diabetic patients (5 males and 3 females, aged 62∼81 years with a mean age of 75±8 years), who were accompanied with chronic below-the-ankle arterial occlusive disease, after the standard transtibial subintimal angioplasty had failed. Both before and after the procedure the clinical symptoms, dorsal or plantar arterial pulse volume scores and ankle-brachial indexes (ABI) were determined in all patients, the results were compared and statistically analysed. During the follow-up period, the degree of pain relief, the healing of the wound, the salvage of the diseased limb and the restenosis occurrence of the target vessels were evaluated. Results: Of the total 8 patients, TDP or TPD retrograde intraluminal re-entry angioplasty was successfully performed in 5(62.5%). After the treatment the foot pain was markedly relieved, the median pulse volume scores and ankle-brachial indexes were increased from 0.60±0.55 and 0.32±0.20 before the procedure to 2.40±0.55 and 0.75±0.12 after the procedure, respectively (P<0.01 for both). At the end of the follow-up lasting for twelve months, the visual analogue scale was apparently improved, the scores decreased from preoperative 7.40±1.14 to 2.20±1.48 (P=0.002). Of two cases with intractable skin ulcer, the skin lesion was completely healed in one and was significantly decreased in size in another. No amputation surgery was needed in all successfully treated patients. Magnetic resonance angiography revealed that one target vessel developed re-stenosis. Conclusion: TDP and TDP retrograde intraluminal re-entry techniques are clinically feasible and effective for the

  4. Data Stream Processing Study in a Multichannel Telemetry Data Registering System

    Directory of Open Access Journals (Sweden)

    I. M. Sidyakin

    2015-01-01

    Full Text Available The paper presents the results of research that is aimed to improve the reliability of transmission of telemetry information (TMI through a communication channel with noise from the object of telemeasurements to the telemetry system for collecting and processing data. It considers the case where the quality of received information changes over time, due to movement of the object relative to the receiving station, or other factors that cause changes in the characteristics of noise in the channel, up to the total loss due to some temporary sites. To improve the reliability of transmission and ensure continuous communication with the object, it is proposed to use a multi-channel system to record the TMI. This system consists of several telemetry stations, which simultaneously register data stream transmitted from the telemetry object. The multichannel system generates a single stream of TMI for the user at the output. The stream comprises the most reliable pieces of information, being received at all inputs of the system.The paper investigates the task of constructing a multi-channel registration scheme for telemetry information (TMI to provide a simultaneous reception of the telemeasurement data by multiple telemetry stations and to form a single TMI stream containing the most reliable pieces of received data on the basis of quality analysis of information being received.In a multichannel registering system of TMI there are three main factors affecting the quality of the output of a single stream of information: 1 quality of the method used for protecting against errors during transmission over the communication channel with noise; 2 efficiency of the synchronization process of telemetry frames in the received flow of information; 3 efficiency of the applied criteria to form a single output stream from multiple input streams coming from different stations in the discussed multichannel registering system of TMI.In the paper, in practical

  5. Relativistic Multichannel Treatment of Krypton Spectra across the First Ionization Threshold

    Institute of Scientific and Technical Information of China (English)

    QU Yi-Zhi; PENG Yong-Lun

    2005-01-01

    @@ The relativistic multichannel theory has been extended to calculate both the eigen quantum defects μα, transformation matrix Uiα, and the eigen dipole matrix elements Dα of krypton. The Rydberg and autoionizationspectra of krypton across the first ionization threshold are calculated within the framework of multichannel quantum defect theory. Our calculated spectra are in agreement with the absolute measurement data.

  6. Multi-channel distributed coordinated function over single radio in wireless sensor networks.

    Science.gov (United States)

    Campbell, Carlene E-A; Loo, Kok-Keong Jonathan; Gemikonakli, Orhan; Khan, Shafiullah; Singh, Dhananjay

    2011-01-01

    Multi-channel assignments are becoming the solution of choice to improve performance in single radio for wireless networks. Multi-channel allows wireless networks to assign different channels to different nodes in real-time transmission. In this paper, we propose a new approach, Multi-channel Distributed Coordinated Function (MC-DCF) which takes advantage of multi-channel assignment. The backoff algorithm of the IEEE 802.11 distributed coordination function (DCF) was modified to invoke channel switching, based on threshold criteria in order to improve the overall throughput for wireless sensor networks (WSNs) over 802.11 networks. We presented simulation experiments in order to investigate the characteristics of multi-channel communication in wireless sensor networks using an NS2 platform. Nodes only use a single radio and perform channel switching only after specified threshold is reached. Single radio can only work on one channel at any given time. All nodes initiate constant bit rate streams towards the receiving nodes. In this work, we studied the impact of non-overlapping channels in the 2.4 frequency band on: constant bit rate (CBR) streams, node density, source nodes sending data directly to sink and signal strength by varying distances between the sensor nodes and operating frequencies of the radios with different data rates. We showed that multi-channel enhancement using our proposed algorithm provides significant improvement in terms of throughput, packet delivery ratio and delay. This technique can be considered for WSNs future use in 802.11 networks especially when the IEEE 802.11n becomes popular thereby may prevent the 802.15.4 network from operating effectively in the 2.4 GHz frequency band.

  7. Multichannel imager for littoral zone characterization

    Science.gov (United States)

    Podobna, Yuliya; Schoonmaker, Jon; Dirbas, Joe; Sofianos, James; Boucher, Cynthia; Gilbert, Gary

    2010-04-01

    This paper describes an approach to utilize a multi-channel, multi-spectral electro-optic (EO) system for littoral zone characterization. Advanced Coherent Technologies, LLC (ACT) presents their EO sensor systems for the surf zone environmental assessment and potential surf zone target detection. Specifically, an approach is presented to determine a Surf Zone Index (SZI) from the multi-spectral EO sensor system. SZI provides a single quantitative value of the surf zone conditions delivering an immediate understanding of the area and an assessment as to how well an airborne optical system might perform in a mine countermeasures (MCM) operation. Utilizing consecutive frames of SZI images, ACT is able to measure variability over time. A surf zone nomograph, which incorporates targets, sensor, and environmental data, including the SZI to determine the environmental impact on system performance, is reviewed in this work. ACT's electro-optical multi-channel, multi-spectral imaging system and test results are presented and discussed.

  8. A multi-channel isolated power supply in non-equipotential circuit

    Science.gov (United States)

    Li, Xiang; Zhao, Bo-Wen; Zhang, Yan-Chi; Xie, Da

    2018-04-01

    A multi-channel isolation power supply is designed for the problems of different MOSFET or IGBT in the non-equipotential circuit in this paper. It mainly includes the square wave generation circuit, the high-frequency transformer and the three-terminal stabilized circuit. The first part is used to generate the 24V square wave, and as the input of the magnetic ring transformer. In the second part, the magnetic ring transformer consists of one input and three outputs to realize multi-channel isolation output. The third part can output different potential and realize non-equal potential function through the three-terminal stabilized chip. In addition, the multi-channel isolation power source proposed in this paper is Small size, high reliability and low price, and it is convenient for power electronic switches that operate on multiple different potentials. Therefore, the research on power supply of power electronic circuit has practical significance.

  9. Evaluation of Multi-Channel ADCs for Gamma-Ray Spectroscopy

    Science.gov (United States)

    Tan, Hui; Hennig, Wolfgang; Walby, Mark D.; Breus, Dimitry; Harris, Jackson

    2013-04-01

    As nuclear physicists increasingly design large scale experiments with hundreds or thousands of detector channels, there are growing needs for high density readout electronics with good timing and energy resolution that at the same time offer lower cost per channel compared to existing commercial solutions. Recent improvements in the design of commercial analog to digital converters (ADCs) have resulted in a variety of multi-channel ADCs that are natural choice for designing such high density readout modules. However, multi-channel ADCs typically are designed for medical imaging/ultrasound applications and therefore are not rated for their spectroscopic characteristics. In this work, we evaluated the gamma-ray spectroscopic performance of several multi-channel ADCs, including their energy resolution, nonlinearity, and timing resolution. Some of these ADCs demonstrated excellent energy resolution, 2.66% FWHM at 662 keV with a LaBr3 or 1.78 keV FWHM at 1332.5 keV with a high purity germanium (HPGe) detector, and sub-nanosecond timing resolution with LaBr 3. We present results from these measurements to illustrate their suitability for gamma-ray spectroscopy.

  10. A-Source Impedance Network

    DEFF Research Database (Denmark)

    Siwakoti, Yam Prasad; Blaabjerg, Frede; Galigekere, Veda Prakash

    2016-01-01

    A novel A-source impedance network is proposed in this letter. The A-source impedance network uses an autotransformer for realizing converters for any application that demand a very high dc voltage gain. The network utilizes a minimal turns ratio compared to other Magnetically Coupled Impedance S...

  11. Design of multichannel counting system for IBM PC and compatibles

    International Nuclear Information System (INIS)

    Majeed, B.; Ahmad, Z.; Osman, A.; Ysain, M.M.

    1995-07-01

    A Multichannel Counting System (MCCS), based on IBM-PC and compatible computer systems have been designed. The MCCS consists of a Multichannel Counting System plug-in interface card (MCCS-PC) for IBM PC and compatibles and a NIM-BIN module (MCCS-NB). The MCCS-PC provides simultaneous monitoring of upto seven independent SCA type inputs. An on board programmable timer provides elapsed time measurement. A menu-driven program for data acquisition and timer control has also been developed. (author) 8 figs

  12. Artificial Walking Technologies to Improve Gait in Cerebral Palsy: Multichannel Neuromuscular Stimulation.

    Science.gov (United States)

    Rose, Jessica; Cahill-Rowley, Katelyn; Butler, Erin E

    2017-11-01

    Cerebral palsy (CP) is the most common childhood motor disability and often results in debilitating walking abnormalities, such as flexed-knee and stiff-knee gait. Current medical and surgical treatments are only partially effective in improving gait abnormalities and may cause significant muscle weakness. However, emerging artificial walking technologies, such as step-initiated, multichannel neuromuscular electrical stimulation (NMES), can substantially improve gait patterns and promote muscle strength in children with spastic CP. NMES may also be applied to specific lumbar-sacral sensory roots to reduce spasticity. Development of tablet computer-based multichannel NMES can leverage lightweight, wearable wireless stimulators, advanced control design, and surface electrodes to activate lower-limb muscles. Musculoskeletal models have been used to characterize muscle contributions to unimpaired gait and identify high muscle demands, which can help guide multichannel NMES-assisted gait protocols. In addition, patient-specific NMES-assisted gait protocols based on 3D gait analysis can facilitate the appropriate activation of lower-limb muscles to achieve a more functional gait: stance-phase hip and knee extension and swing-phase sequence of hip and knee flexion followed by rapid knee extension. NMES-assisted gait treatment can be conducted as either clinic-based or home-based programs. Rigorous testing of multichannel NMES-assisted gait training protocols will determine optimal treatment dosage for future clinical trials. Evidence-based outcome evaluation using 3D kinematics or temporal-spatial gait parameters will help determine immediate neuroprosthetic effects and longer term neurotherapeutic effects of step-initiated, multichannel NMES-assisted gait in children with spastic CP. Multichannel NMES is a promising assistive technology to help children with spastic CP achieve a more upright, functional gait. © 2017 International Center for Artificial Organs and

  13. Research on digital multi-channel pulse height analysis techniques

    International Nuclear Information System (INIS)

    Xiao Wuyun; Wei Yixiang; Ai Xianyun; Ao Qi

    2005-01-01

    Multi-channel pulse height analysis techniques are developing in the direction of digitalization. Based on digital signal processing techniques, digital multi-channel analyzers are characterized by powerful pulse processing ability, high throughput, improved stability and flexibility. This paper analyzes key techniques of digital nuclear pulse processing. With MATLAB software, main algorithms are simulated, such as trapezoidal shaping, digital baseline estimation, digital pole-zero/zero-pole compensation, poles and zeros identification. The preliminary general scheme of digital MCA is discussed, as well as some other important techniques about its engineering design. All these lay the foundation of developing homemade digital nuclear spectrometers. (authors)

  14. Intraluminal filling defects of the bile ducts: differentiation of stones from tumors-the value of magnetic resonance cholangiography in conjunction with a 3D spoiled gradient echo gadolinium enhanced dynamic sequence

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Soo Jin; Kim, Suk; Kim, Chang Won [Busan National University Hospital, Busan (Korea, Republic of)] (and others)

    2006-05-15

    We wanted to determinate the value of a dynamic volumetric interpolated breath-hold examination (VIBE) as a supplement to MR cholangiography for differentiating biliary stones from tumors when patient are suspected of having intraluminal filling defects on direct cholangiography. A retrospective analysis was performed for 49 patients who underwent MRI among all the patients who showed intraluminal filling defects on direct cholangiography for evaluating the cause of their jaundice from June 2002 to June 2003. After dividing these patients into two groups; i.e., the group with stones and the group wth tumors, we analyzed and compared each MR patterns of 1) signal intensity, 2) shape, and 3) enhancement. High signal intensity on T1-weighted images ({rho} < 0.001, X{sup 2} test), dark signal intensity on T2-weighted images ({rho} < 0.01, Fisher' s exact test) or smooth contour of intraluminal filling defects ({rho} < 0.001, X{sup 2} test) could be significantly suggestive findings of stone rather than a tumor mass. Dynamic VIBE is the most specific sequence for differentiating non-enhancing stone from an enhancing mass ({rho} < 0.001, Fisher' s exact test). We showed that MR cholangiography, when added to the dynamic VIBE sequences, could be an important imaging technique for patients who are suspected of having intraluminal filling defects on direct cholangiography to differentiate stones from tumors. Especially, the addition of dynamic VIBE images can provide the increased level of confidence in the diagnosis.

  15. Multichannel Human Body Communication

    International Nuclear Information System (INIS)

    Przystup, Piotr; Bujnowski, Adam; Wtorek, Jerzy

    2016-01-01

    Human Body Communication is an attractive alternative for traditional wireless communication (Bluetooth, ZigBee) in case of Body Sensor Networks. Low power, high data rates and data security makes it ideal solution for medical applications. In this paper, signal attenuation for different frequencies, using FR4 electrodes, has been investigated. Performance of single and multichannel transmission with frequency modulation of analog signal has been tested. Experiment results show that HBC is a feasible solution for transmitting data between BSN nodes

  16. Challenges and opportunities in multichannel customer management

    NARCIS (Netherlands)

    Neslin, Scott A.; Grewal, Dhruv; Leghorn, Robert; Shankar, Venkatesh; Teerling, Marije L.; Thomas, Jacquelyn S.; Verhoef, Peter C.

    Multichannel customer management is the design, deployment, coordination, and evaluation of channels through which firms and customers interact, with the goal of enhancing customer value through effective customer acquisition, retention, and development. The authors identify five major challenges

  17. Challenges and opportunities in multichannel customer management

    NARCIS (Netherlands)

    Neslin, Scott A.; Grewal, Dhruv; Leghorn, Robert; Shankar, Venkatesh; Teerling, Marije L.; Thomas, Jacquelyn S.; Verhoef, Peter C.

    2006-01-01

    Multichannel customer management is the design, deployment, coordination, and evaluation of channels through which firms and customers interact, with the goal of enhancing customer value through effective customer acquisition, retention, and development. The authors identify five major challenges

  18. Balloon expandable intraluminal grafting of normal and abnormal renal arteries: Experimental study

    International Nuclear Information System (INIS)

    Palmaz, J.C.; Hayashi, H.; Schatz, R.; Hunter, G.; Tio, F.O.; Garcia, O.

    1986-01-01

    Balloon expandable intraluminal grafts were placed in renal arteries of eight adult dogs and 11 minipigs. The renal arteries were normal in the dogs before graft placement. Two grafts were placed in primary division branches and the rest in the main renal artery. Experimental renal artery stenosis was created in the minipigs by subocclusive ligature of the renal artery with absorbable suture material. Six months later significant renal artery stenoses developed in six pigs and were corrected by graft placement. In the remaining pigs grafts were placed in the opposite normal renal artery because the stenosis caused a small, shrunken kidney in two, and severe spasm or anatomic variations prevented graft placement in three. All grafts remained patent on angiographic and pathologic examinations to a maximum follow-up to 24 weeks

  19. Multichannel sound reinforcement systems at work in a learning environment

    Science.gov (United States)

    Malek, John; Campbell, Colin

    2003-04-01

    Many people have experienced the entertaining benefits of a surround sound system, either in their own home or in a movie theater, but another application exists for multichannel sound that has for the most part gone unused. This is the application of multichannel sound systems to the learning environment. By incorporating a 7.1 surround processor and a touch panel interface programmable control system, the main lecture hall at the University of Michigan Taubman College of Architecture and Urban Planning has been converted from an ordinary lecture hall to a working audiovisual laboratory. The multichannel sound system is used in a wide variety of experiments, including exposure to sounds to test listeners' aural perception of the tonal characteristics of varying pitch, reverberation, speech transmission index, and sound-pressure level. The touch panel's custom interface allows a variety of user groups to control different parts of the AV system and provides preset capability that allows for numerous system configurations.

  20. Multi-channel motor evoked potential monitoring during anterior cervical discectomy and fusion

    Directory of Open Access Journals (Sweden)

    Dong-Gun Kim

    Full Text Available Objectives: Anterior cervical discectomy and fusion (ACDF surgery is the most common surgical procedure for the cervical spine with low complication rate. Despite the potential prognostic benefit, intraoperative neurophysiological monitoring (IONM, a method for detecting impending neurological compromise, is not routinely used in ACDF surgery. The present study aimed to identify the potential benefits of monitoring multi-channel motor evoked potentials (MEPs during ACDF surgery. Methods: We retrospectively reviewed 200 consecutive patients who received IONM with multi-channel MEPs and somatosensory evoked potentials (SSEPs. On average, 9.2 muscles per patient were evaluated under MEP monitoring. Results: The rate of MEP change during surgery in the multi-level ACDF group was significantly higher than the single-level group. Two patients from the single-level ACDF group (1.7% and four patients from the multi-level ACDF group (4.9% experienced post-operative motor deficits. Multi-channel MEPs monitoring during single and multi-level ACDF surgery demonstrated higher sensitivity, specificity, positive predictive and negative predictive value than SSEP monitoring. Conclusions: Multi-channel MEP monitoring might be beneficial for the detection of segmental injury as well as long tract injury during single- and multi-level ACDF surgery. Significance: This is first large scale study to identify the usefulness of multi-channel MEPs in monitoring ACDF surgery. Keywords: Disc disease, Somatosensory evoked potentials, Intraoperative neurophysiological monitoring, Motor evoked potentials, Anterior cervical discectomy and fusion

  1. Gastric emptying and gastro-oesophageal reflux in children with cystic fibrosis.

    Science.gov (United States)

    Hauser, Bruno; De Schepper, Jean; Malfroot, Anne; De Wachter, Elke; De Schutter, Iris; Keymolen, Kathelijn; Vandenplas, Yvan

    2016-07-01

    Gastro-oesophageal reflux (GOR) is common in patients with cystic fibrosis (CF). The aim of this study was to investigate the relationship between gastric emptying (GE) and GOR in children with CF. Multichannel intraluminal impedance-pH monitoring (MII-pH) to measure GOR and GE breath test (GEBT) to measure GE were performed in 28 children with symptoms suggestive for GOR disease (GORD) (group 1). GEBT was performed in another 28 children with/without GOR symptoms who agreed to undergo GEBT but not MII-pH (group 2). In group 1, we found increased acid GOR (AGOR) in 46.4% and delayed GE (DGE) in 21.4% but no relationship between increased AGOR and DGE. There was no DGE in group 2. We found DGE in 10.7% and rapid GE in 12.5% of the whole group. Almost half of the children with CF and symptoms suggestive for GORD have increased AGOR and almost a quarter has DGE. However, there was no relation between GOR and GE. Copyright © 2015 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.

  2. Functional Heartburn Overlaps With Irritable Bowel Syndrome More Often than GERD.

    Science.gov (United States)

    de Bortoli, Nicola; Frazzoni, Leonardo; Savarino, Edoardo V; Frazzoni, Marzio; Martinucci, Irene; Jania, Aleksandra; Tolone, Salvatore; Scagliarini, Michele; Bellini, Massimo; Marabotto, Elisa; Furnari, Manuele; Bodini, Giorgia; Russo, Salvatore; Bertani, Lorenzo; Natali, Veronica; Fuccio, Lorenzo; Savarino, Vincenzo; Blandizzi, Corrado; Marchi, Santino

    2016-12-01

    We aimed to evaluate the prevalence of irritable bowel syndrome (IBS) in patients with typical reflux symptoms as distinguished into gastroesophageal reflux disease (GERD), hypersensitive esophagus (HE), and functional heartburn (FH) by means of endoscopy and multichannel intraluminal impedance (MII)-pH monitoring. The secondary aim was to detect pathophysiological and clinical differences between different sub-groups of patients with heartburn. Patients underwent a structured interview based on questionnaires for GERD, IBS, anxiety, and depression. Off-therapy upper-gastrointestinal (GI) endoscopy and 24 h MII-pH monitoring were performed in all cases. In patients with IBS, fecal calprotectin was measured and colonoscopy was scheduled for values >100 mg/kg to exclude organic disease. Multivariate logistic regression analysis was performed to identify independent risk factors for FH. Of the 697 consecutive heartburn patients who entered the study, 454 (65%) had reflux-related heartburn (GERD+HE), whereas 243 (35%) had FH. IBS was found in 147/454 (33%) GERD/HE but in 187/243 (77%) FH patients (Pheartburn (GERD+HE). IBS overlaps more frequently with FH than with GERD and HE, suggesting common pathways and treatment. HE showed intermediate characteristic between GERD and FH.

  3. Esophageal Motility and Rikkunshito Treatment for Proton Pump Inhibitor-Refractory Nonerosive Reflux Disease: A Prospective, Uncontrolled, Open-Label Pilot Study Trial.

    Science.gov (United States)

    Odaka, Takeo; Yamato, Shigeru; Yokosuka, Osamu

    2017-01-01

    Only a few reports focused on esophageal motility in patients with proton pump inhibitor (PPI)-refractory nonerosive reflux disease (NERD) and there has been no established strategy for treatment. To clarify the characteristics of esophageal motility in patients with PPI-refractory NERD, we evaluated esophageal function using combined multichannel intraluminal impedance and esophageal manometry (MII-EM). In addition, we evaluated the efficacy of rikkunshito (RKT), which is a gastrointestinal prokinetic agent. Thirty patients with NERD were enrolled and underwent MII-EM. After 8 weeks of RKT (7.5 g/d) treatment, MII-EM was repeated on patients with PPI-refractory NERD. Symptoms were assessed by the Gastrointestinal Symptom Rating Scale. In patients with PPI-refractory NERD, measures of complete bolus transit, peristaltic contractions, and residual pressure of the lower esophageal sphincter during swallowing deviated from the standard values and esophageal clearance was found to be deteriorated. RKT significantly improved the peristaltic contractions ( P esophageal sphincter ( P disorders of esophageal and lower esophageal sphincter motility that were improved by RKT. Further studies examining esophageal motor activity of RKT in PPI-refractory NERD are required. University hospital Medical Information Network (UMIN) Clinical Trial Registry identifier: UMIN000003092.

  4. Diagnosis and treatment of patients with nonacid gastroesophageal reflux-induced chronic cough

    Directory of Open Access Journals (Sweden)

    Xianghuai Xu

    2015-01-01

    Full Text Available Gastroesophageal reflux (GER is one of the most common causes of chronic cough, and chronic cough due to GER represents a subtype of GER-related diseases. Gastroesophageal reflux-induced chronic cough (GERC can be divided into two subgroups based on the pH of the GER. Nonacid GERC is less common than acid GERC, and its diagnosis and treatment strategy have not been standardized. However, nonacid GERC usually presents with its unique set of characteristics and features upon diagnosis and treatment in the clinic. Although the underlying molecular mechanism of nonacid GERC is not fully understood, it is considered to be associated with reflux theory, reflex theory and airway hypersensitivity. Multi-channel intraluminal impedance combined with pH monitoring is a promising new technique that can detect both acid and nonacid reflux, and our findings as well as those of others have shown its usefulness in diagnosing nonacid GERC. Development of new diagnostic techniques has led to an increased rate of nonacid GERC diagnosis. We summarize our experience in the diagnosis and treatment of nonacid GERC and provide a guide for future therapeutic approaches.

  5. Multichannel analyzer based on microprocessors

    International Nuclear Information System (INIS)

    Soares, M.

    1983-06-01

    A multichannel analyser for nuclear spectrometry, that would attend the needs of research laboratories and could be industrialized in Brazil, was developed. The design was based on INTEL 8080/85 microprocessors; other processors were also used to implement specific functions, such as shared busbar using direct memory access. A prototype was developed and tested through simulation, using a nuclear spectrometry chain. The results were fully satisfactory. (Author) [pt

  6. Impeded Dark Matter

    Energy Technology Data Exchange (ETDEWEB)

    Kopp, Joachim; Liu, Jia [PRISMA Cluster of Excellence & Mainz Institute for Theoretical Physics,Johannes Gutenberg University,Staudingerweg 7, 55099 Mainz (Germany); Slatyer, Tracy R. [Center for Theoretical Physics, Massachusetts Institute of Technology,Cambridge, MA 02139 (United States); Wang, Xiao-Ping [PRISMA Cluster of Excellence & Mainz Institute for Theoretical Physics,Johannes Gutenberg University,Staudingerweg 7, 55099 Mainz (Germany); Xue, Wei [Center for Theoretical Physics, Massachusetts Institute of Technology,Cambridge, MA 02139 (United States)

    2016-12-12

    We consider dark matter models in which the mass splitting between the dark matter particles and their annihilation products is tiny. Compared to the previously proposed Forbidden Dark Matter scenario, the mass splittings we consider are much smaller, and are allowed to be either positive or negative. To emphasize this modification, we dub our scenario “Impeded Dark Matter”. We demonstrate that Impeded Dark Matter can be easily realized without requiring tuning of model parameters. For negative mass splitting, we demonstrate that the annihilation cross-section for Impeded Dark Matter depends linearly on the dark matter velocity or may even be kinematically forbidden, making this scenario almost insensitive to constraints from the cosmic microwave background and from observations of dwarf galaxies. Accordingly, it may be possible for Impeded Dark Matter to yield observable signals in clusters or the Galactic center, with no corresponding signal in dwarfs. For positive mass splitting, we show that the annihilation cross-section is suppressed by the small mass splitting, which helps light dark matter to survive increasingly stringent constraints from indirect searches. As specific realizations for Impeded Dark Matter, we introduce a model of vector dark matter from a hidden SU(2) sector, and a composite dark matter scenario based on a QCD-like dark sector.

  7. Impeded Dark Matter

    International Nuclear Information System (INIS)

    Kopp, Joachim; Liu, Jia; Slatyer, Tracy R.; Wang, Xiao-Ping; Xue, Wei

    2016-01-01

    We consider dark matter models in which the mass splitting between the dark matter particles and their annihilation products is tiny. Compared to the previously proposed Forbidden Dark Matter scenario, the mass splittings we consider are much smaller, and are allowed to be either positive or negative. To emphasize this modification, we dub our scenario “Impeded Dark Matter”. We demonstrate that Impeded Dark Matter can be easily realized without requiring tuning of model parameters. For negative mass splitting, we demonstrate that the annihilation cross-section for Impeded Dark Matter depends linearly on the dark matter velocity or may even be kinematically forbidden, making this scenario almost insensitive to constraints from the cosmic microwave background and from observations of dwarf galaxies. Accordingly, it may be possible for Impeded Dark Matter to yield observable signals in clusters or the Galactic center, with no corresponding signal in dwarfs. For positive mass splitting, we show that the annihilation cross-section is suppressed by the small mass splitting, which helps light dark matter to survive increasingly stringent constraints from indirect searches. As specific realizations for Impeded Dark Matter, we introduce a model of vector dark matter from a hidden SU(2) sector, and a composite dark matter scenario based on a QCD-like dark sector.

  8. Observations involving broadband impedance modelling

    Energy Technology Data Exchange (ETDEWEB)

    Berg, J S [Stanford Linear Accelerator Center, Menlo Park, CA (United States)

    1996-08-01

    Results for single- and multi-bunch instabilities can be significantly affected by the precise model that is used for the broadband impedance. This paper discusses three aspects of broadband impedance modelling. The first is an observation of the effect that a seemingly minor change in an impedance model has on the single-bunch mode coupling threshold. The second is a successful attempt to construct a model for the high-frequency tails of an r.f. cavity. The last is a discussion of requirements for the mathematical form of an impedance which follow from the general properties of impedances. (author)

  9. Role of the intraluminal contents and the continuity of intrinsic neurons in intracolonic capsaicin-induced contraction and defecation in dogs.

    Science.gov (United States)

    Kikuchi, Daisuke; Shibata, Chikashi; Imoto, Hirofumi; Someya, Soutoku; Miyachi, Tomohiro; Miura, Koh; Naitoh, Takeshi; Unno, Michiaki

    2014-01-01

    We, herein, examined the role of the intraluminal contents and continuity of colonic intrinsic neurons in intracolonic capsaicin-induced enhancement of colonic motility and defecation. Five beagle dogs were equipped with three strain gauge force transducers throughout the colon. The colonic contractile activity in response to intracolonic capsaicin was studied in intact dogs, dogs after colonic cleansing and dogs with transection/re-anastomosis (T/R) between the proximal and middle colon. The effects of intravenous yohimbine, a α2 adrenergic antagonist, on the colonic motility and defecation were also studied in the same models. In intact dogs, capsaicin (10 mg) and yohimbine (2 mg/kg) immediately induced contractions throughout the colon, with defecation occurring in all experiments. In dogs after colonic cleansing and T/R, the capsaicin (10 mg)-induced enhancement of colonic motility was decreased in the middle and distal colon, and capsaicin-induced defecation was observed in 0-20 % of experiments (p continuity of the colonic intrinsic nerves as well as the intraluminal contents appear to play an important role in the colonic motor response to intracolonic capsaicin.

  10. Multi-channel service concept design and prototyping

    NARCIS (Netherlands)

    Sperling, C.P.; Simons, L.P.A.; Bouwman, W.A.G.A.

    2007-01-01

    Designing e-services which have to function in a multi-channel context has proved to be challenging for organizations. Previous research has shown that structured design methods are useful to structure the design process. In this paper we proceed from an existing method (which identifies

  11. Measurement errors in multifrequency bioelectrical impedance analyzers with and without impedance electrode mismatch

    International Nuclear Information System (INIS)

    Bogónez-Franco, P; Nescolarde, L; Bragós, R; Rosell-Ferrer, J; Yandiola, I

    2009-01-01

    The purpose of this study is to compare measurement errors in two commercially available multi-frequency bioimpedance analyzers, a Xitron 4000B and an ImpediMed SFB7, including electrode impedance mismatch. The comparison was made using resistive electrical models and in ten human volunteers. We used three different electrical models simulating three different body segments: the right-side, leg and thorax. In the electrical models, we tested the effect of the capacitive coupling of the patient to ground and the skin–electrode impedance mismatch. Results showed that both sets of equipment are optimized for right-side measurements and for moderate skin–electrode impedance mismatch. In right-side measurements with mismatch electrode, 4000B is more accurate than SFB7. When an electrode impedance mismatch was simulated, errors increased in both bioimpedance analyzers and the effect of the mismatch in the voltage detection leads was greater than that in current injection leads. For segments with lower impedance as the leg and thorax, SFB7 is more accurate than 4000B and also shows less dependence on electrode mismatch. In both devices, impedance measurements were not significantly affected (p > 0.05) by the capacitive coupling to ground

  12. Wavelet compression of multichannel ECG data by enhanced set partitioning in hierarchical trees algorithm.

    Science.gov (United States)

    Sharifahmadian, Ershad

    2006-01-01

    The set partitioning in hierarchical trees (SPIHT) algorithm is very effective and computationally simple technique for image and signal compression. Here the author modified the algorithm which provides even better performance than the SPIHT algorithm. The enhanced set partitioning in hierarchical trees (ESPIHT) algorithm has performance faster than the SPIHT algorithm. In addition, the proposed algorithm reduces the number of bits in a bit stream which is stored or transmitted. I applied it to compression of multichannel ECG data. Also, I presented a specific procedure based on the modified algorithm for more efficient compression of multichannel ECG data. This method employed on selected records from the MIT-BIH arrhythmia database. According to experiments, the proposed method attained the significant results regarding compression of multichannel ECG data. Furthermore, in order to compress one signal which is stored for a long time, the proposed multichannel compression method can be utilized efficiently.

  13. Computationally Developed Sham Stimulation Protocol for Multichannel Desynchronizing Stimulation

    Directory of Open Access Journals (Sweden)

    Magteld Zeitler

    2018-05-01

    Full Text Available A characteristic pattern of abnormal brain activity is abnormally strong neuronal synchronization, as found in several brain disorders, such as tinnitus, Parkinson's disease, and epilepsy. As observed in several diseases, different therapeutic interventions may induce a placebo effect that may be strong and hinder reliable clinical evaluations. Hence, to distinguish between specific, neuromodulation-induced effects and unspecific, placebo effects, it is important to mimic the therapeutic procedure as precisely as possibly, thereby providing controls that actually lack specific effects. Coordinated Reset (CR stimulation has been developed to specifically counteract abnormally strong synchronization by desynchronization. CR is a spatio-temporally patterned multichannel stimulation which reduces the extent of coincident neuronal activity and aims at an anti-kindling, i.e., an unlearning of both synaptic connectivity and neuronal synchrony. Apart from acute desynchronizing effects, CR may cause sustained, long-lasting desynchronizing effects, as already demonstrated in pre-clinical and clinical proof of concept studies. In this computational study, we set out to computationally develop a sham stimulation protocol for multichannel desynchronizing stimulation. To this end, we compare acute effects and long-lasting effects of six different spatio-temporally patterned stimulation protocols, including three variants of CR, using a no-stimulation condition as additional control. This is to provide an inventory of different stimulation algorithms with similar fundamental stimulation parameters (e.g., mean stimulation rates but qualitatively different acute and/or long-lasting effects. Stimulation protocols sharing basic parameters, but inducing nevertheless completely different or even no acute effects and/or after-effects, might serve as controls to validate the specific effects of particular desynchronizing protocols such as CR. In particular, based on

  14. On the use of A PCA as a multichannel time analyzer

    International Nuclear Information System (INIS)

    Adib, M.; Abdelkawy, A.; Abuelela, M.; Habib, N.; Wahba, M.; Salama, F.

    1992-01-01

    PCA and PCA-11 software programmes have been used to utilize the operation of the nucleus personal computer analyzer PCA-8000 in its multichannel scaler (MCS) mode. The operating condition of PCA-8000 were selected to match the time-of-flight (TOF) spectrometer which is in operation at the ET-RR-1 reactor. The results of measuring the main parameters of PCA-8000 operating in its MCS mode showed that it can be successfully used as a multichannel time analyzer.5 fig

  15. Impedance analysis of subwoofer systems

    NARCIS (Netherlands)

    Berkhoff, Arthur P.

    The electrical impedance of four low-frequency loudspeaker systems is analyzed. The expression for this impedance is obtained directly from the acoustical analogous circuit. Formulas are derived for calculating the small-signal parameters from the frequencies of impedance minima and maxima of two

  16. Multichannel CdZnTe Gamma Ray Spectrometer

    International Nuclear Information System (INIS)

    Doty, F.P.; Lingren, C. L.; Apotovsky, B. A.; Brunsch, J.; Butler, J. F.; Collins, T.; Conwell, R.L.; Friesenhahn, S.; Gormley, J.; Pi, B.; Zhao, S.; Augustine, F.L.; Bennet, B. A.; Cross, E.; James, R. B.

    1998-01-01

    A 3 cm 3 multichannel gamma spectrometer for DOE applications is under development by Digirad Corporation. The device is based on a position sensitive detector packaged in a compact multi-chip module (MCM) with integrated readout circuitry. The modular, multichannel design will enable identification and quantitative analysis of radionuclides in extended sources, or sources containing low levels of activity. The MCM approach has the advantages that the modules are designed for imaging applications, and the sensitivity can be arbitrarily increased by increasing the number of pixels, i.e. adding modules to the instrument. For a high sensitivity probe, the outputs for each pixel can be corrected for gain and offset variations, and summed digitally. Single pixel results obtained with discrete low noise readout indicate energy resolution of 3 keV can be approached with currently available CdZnTe. The energy resolution demonstrated to date with MCMs for 511 keV gamma rays is 10 keV

  17. Impedance Source Power Electronic Converters

    DEFF Research Database (Denmark)

    Liu, Yushan; Abu-Rub, Haitham; Ge, Baoming

    Impedance Source Power Electronic Converters brings together state of the art knowledge and cutting edge techniques in various stages of research related to the ever more popular impedance source converters/inverters. Significant research efforts are underway to develop commercially viable...... and technically feasible, efficient and reliable power converters for renewable energy, electric transportation and for various industrial applications. This book provides a detailed understanding of the concepts, designs, controls, and application demonstrations of the impedance source converters/inverters. Key...... features: Comprehensive analysis of the impedance source converter/inverter topologies, including typical topologies and derived topologies. Fully explains the design and control techniques of impedance source converters/inverters, including hardware design and control parameter design for corresponding...

  18. Beam measurements of the LHC impedance and validation of the impedance model

    CERN Document Server

    Esteban Müller, J F; Bohl, T; Mounet, N; Shaposhnikova, E; Timko, H

    2014-01-01

    Different measurements of the longitudinal impedance of the LHC done with single bunches with various intensities and longitudinal emittances during measurement sessions in 2011-2012 are compared with particle simulations based on the existing LHC impedance model. The very low reactive impedance of the LHC, with Im Z=n = 0.08, is not easy to measure. The most sensitive observation is the loss of Landau damping, which shows at which energy bunches become unstable depending on their parameters. In addition, the synchrotron frequency shift due to the reactive impedance was estimated following two methods. Firstly, it was obtained from the peak-detected Schottky spectrum. Secondly, a sine modulation in the RF phase was applied to the bunches of different intensities and the modulation frequency was scanned. In both cases, the synchrotron frequency shift was of the order of the measurement precision.

  19. Microwave Impedance Measurement for Nanoelectronics

    Directory of Open Access Journals (Sweden)

    M. Randus

    2011-04-01

    Full Text Available The rapid progress in nanoelectronics showed an urgent need for microwave measurement of impedances extremely different from the 50Ω reference impedance of measurement instruments. In commonly used methods input impedance or admittance of a device under test (DUT is derived from measured value of its reflection coefficient causing serious accuracy problems for very high and very low impedances due to insufficient sensitivity of the reflection coefficient to impedance of the DUT. This paper brings theoretical description and experimental verification of a method developed especially for measurement of extreme impedances. The method can significantly improve measurement sensitivity and reduce errors caused by the VNA. It is based on subtraction (or addition of a reference reflection coefficient and the reflection coefficient of the DUT by a passive network, amplifying the resulting signal by an amplifier and measuring the amplified signal as a transmission coefficient by a common vector network analyzer (VNA. A suitable calibration technique is also presented.

  20. SU-E-T-10: A Clinical Implementation and the Dosimetric Evidence in High Dose Rate Vaginal Multichannel Applicator Brachytherapy

    Energy Technology Data Exchange (ETDEWEB)

    Syh, J; Syh, J; Patel, B; Zhang, J; Wu, H; Rosen, L [Willis-Knighton Medical Center, Shreveport, LA (United States)

    2015-06-15

    Purpose: The multichannel cylindrical applicator has a distinctive modification of the traditional single channel cylindrical applicator. The novel multichannel applicator has additional peripheral channels that provide more flexibility both in treatment planning process and outcomes. To protect by reducing doses to adjacent organ at risk (OAR) while maintaining target coverage with inverse plan optimization are the goals for such novel Brachytherapy device. Through a series of comparison and analysis of reults in more than forty patients who received HDR Brachytherapy using multichannel vaginal applicator, this procedure has been implemented in our institution. Methods: Multichannel planning was CT image based. The CTV of 5mm vaginal cuff rind with prescribed length was well reconstructed as well as bladder and rectum. At least D95 of CTV coverage is 95% of prescribed dose. Multichannel inverse plan optimization algorithm not only shapes target dose cloud but set dose avoids to OAR’s exclusively. The doses of D2cc, D5cc and D5; volume of V2Gy in OAR’s were selected to compare with single channel results when sole central channel is only possibility. Results: Study demonstrates plan superiorly in OAR’s doe reduction in multi-channel plan. The D2cc of the rectum and bladder were showing a little lower for multichannel vs. single channel. The V2Gy of the rectum was 93.72% vs. 83.79% (p=0.007) for single channel vs. multichannel respectively. Absolute reduced mean dose of D5 by multichannel was 17 cGy (s.d.=6.4) and 44 cGy (s.d.=15.2) in bladder and rectum respectively. Conclusion: The optimization solution in multichannel was to maintain D95 CTV coverage while reducing the dose to OAR’s. Dosimetric advantage in sparing critical organs by using a multichannel applicator in HDR Brachytherapy treatment of the vaginal cuff is so promising and has been implemented clinically.

  1. Research on Multichannel Test Device of Missile Fuze

    Directory of Open Access Journals (Sweden)

    Guoyong Zhen

    2014-05-01

    Full Text Available This paper introduces the design of multichannel acquisition circuit based on FPGA which samples and records the Doppler signals, ignition signal and the working condition of fuze security enforcement agencies of missile fuze in real-time in the test of high speed dynamic intersection. Furthermore, for the problem of increasing number of sample channel which causes the complexity of the multiplexer control, a general programmable channel switching method is proposed based on FPGA. In the method, FPGA is the control core, and using the internal ROM resource effectively simplifies the complexity of channel switch in the multichannel acquisition system. This paper analyzes the acquisition system design, and describes the design of hardware circuit and analog switch address coding in detail. The test result shows that the acquisition circuit meets the design requirements with high sampling precision and application value.

  2. Impedance and Collective Effects

    CERN Document Server

    Metral, E; Rumolo, R; Herr, W

    2013-01-01

    This document is part of Subvolume C 'Accelerators and Colliders' of Volume 21 'Elementary Particles' of Landolt-Börnstein - Group I 'Elementary Particles, Nuclei and Atoms'. It contains the Chapter '4 Impedance and Collective Effects' with the content: 4 Impedance and Collective Effects Introduction 4.1 Space Charge 4.2 Wake Fields and Impedances 4.3 Coherent Instabilities 4.4 Landau Damping 4.5 Two-Stream Effects (Electron Cloud and Ions) 4.6 Beam-Beam Effects 4.7 Numerical Modelling

  3. Recent advances in Multi-Channel Algebraic Scattering

    International Nuclear Information System (INIS)

    Karataglidis, S.; Fraser, P. R.; Amos, K.; Canton, L.; Pisent, G.; Svenne, J. P.; Knijff, D. van der

    2011-01-01

    For coupled-channel descriptions of low-energy nucleon-induced interactions involving nuclei with particle-unstable exited states, it is necessary to include the widths of the target states. How those widths may affect the elastic scattering cross sections is examined within the framework of the Multi-Channel Algebraic Scattering (MCAS) method.

  4. Data processing for the multichannel pulse height analysis system ND-50/50, (1)

    International Nuclear Information System (INIS)

    Katagiri, Masaki

    1977-03-01

    The multichannel pulse height analysis system ND-50/50 manufactured by Nuclear Data Inc. consists of a 4096 channel pulse height analyzer and a small computer PDP-8/L (Digital Equipment Corporation). A conversational interpretive language, MACAL (Multichannel Analyzer CALculator) has been developed to analyze gamma-ray spectra in ND-50/50. It is a modification of the FOCAL (FOrmula CALculator) language of Digital Equipment Corporation. MACAL consists of imperative English commands and mathematical expressions, and has standard mathematical functions and functions for controlling the multichannel pulse height analyzer and I/O devices (high-speed reader, high-speed punch, and digital plotter). With MACAL, the following five programs were prepared : 1) program for controlling the multichannel pulse height analyzer and data handling, 2) program for automatically analyzing gamma-ray spectra obtained by germanium detectors, 3) program for automatically measuring characteristics of germanium detectors, 4) program for calculating the center energy of gamma-ray peaks, and 5) program for plotting the pulse height distribution and diagraming the results obtained with the programs. By combining the programs according to experimental purposes, the system can be highly effective. (auth.)

  5. Software for a multichannel acquisition card

    International Nuclear Information System (INIS)

    Arista Romeu, E. J.; Diaz Garcia, A.; Vela Morales, O.

    2013-01-01

    A software developed in C++ for a multichannel acquisition card is presented. The use of an acquisition add-on card with multiple channels is a suitable solution to substitute several instruments, allowing simultaneous acquisition with each channel. In this work, the limitations of a concrete hardware are discussed and also several different approaches have been suggested. Some preliminary results obtained in laboratory conditions are shown. (Author)

  6. A multi-channel waveform digitizer system

    International Nuclear Information System (INIS)

    Bieser, F.; Muller, W.F.J.

    1990-01-01

    The authors report on the design and performance of a multichannel waveform digitizer system for use with the Multiple Sample Ionization Chamber (MUSIC) Detector at the Bevalac. 128 channels of 20 MHz Flash ADC plus 256 word deep memory are housed in a single crate. Digital thresholds and hit pattern logic facilitate zero suppression during readout which is performed over a standard VME bus

  7. Impedance source power electronic converters

    CERN Document Server

    Liu, Yushan; Ge, Baoming; Blaabjerg, Frede; Ellabban, Omar; Loh, Poh Chiang

    2016-01-01

    Impedance Source Power Electronic Converters brings together state of the art knowledge and cutting edge techniques in various stages of research related to the ever more popular impedance source converters/inverters. Significant research efforts are underway to develop commercially viable and technically feasible, efficient and reliable power converters for renewable energy, electric transportation and for various industrial applications. This book provides a detailed understanding of the concepts, designs, controls, and application demonstrations of the impedance source converters/inverters. Key features: Comprehensive analysis of the impedance source converter/inverter topologies, including typical topologies and derived topologies. Fully explains the design and control techniques of impedance source converters/inverters, including hardware design and control parameter design for corresponding control methods. Presents the latest power conversion solutions that aim to advance the role of pow...

  8. Evidence of echoic memory with a multichannel cochlear prosthesis.

    Science.gov (United States)

    Jerger, S; Watkins, M J

    1988-10-01

    Short-term memory was examined in a subject with a multichannel cochlear prosthesis. Serial recall for lists of digits revealed what are widely regarded as the principal hallmarks of echoic memory, namely the recency effect and the suffix effect. Thus, probability of recall increased for the last one or two digits, except when a nominally irrelevant but spoken item was appended to the to-be-remembered list. It appears, therefore, that a multichannel cochlear implant can give rise to not only the perception of, but also an echoic memory for, speech. As with normal subjects, the suffix effect did not occur with a nonspeech suffix, implying that the echoic memory from the prosthesis shows normal sensitivity to the distinction between speech and nonspeech.

  9. Organization of a multichannel analyzer for gamma ray spectrometry

    International Nuclear Information System (INIS)

    Robinet, Genevieve

    1988-06-01

    This report describes the software organization of a medium scale multichannel analyzer for qualitative and quantitative measurements of the gamma rays emitted by radioactive samples. The first part reminds basis of radioactivity, principle of gamma ray detection, and data processing used for interpretation of a nuclear spectrum. The second part describes first the general organization of the software and then gives some details on interactivity, multidetector capabilites, and integration of complex algorithms for peak search and nuclide identification;problems encountered during the design phase are mentioned and solutions are given. Basic ideas are presented for further developments, such as expert system which should improve interpretation of the results. This present software has been integrated in a manufactured multichannel analyzer named 'POLYGAM NU416'. [fr

  10. Multi-channel grouping techniques for conducting reactor safety studies

    International Nuclear Information System (INIS)

    Waltar, A.E.; Wilburn, N.P.

    1975-01-01

    In conducting safety studies for postulated unprotected accidents in an LMFBR system, it is common practice to employ multi-channel coupled neutronics, thermal hydraulics computer programs such as SAS3A or MELT-III. The multichannel feature of such code systems is important if the natural fuel failure incoherencies and the resulting sodium void/fuel motion reactivity feedbacks--which have strong spatial variations--are to be properly modeled. Because of the large amounts of computer time associated with many channel runs, however, there is a strong incentive to conduct parametric studies with as few channels as possible. The paper presented is focused on methods successfully employed to accomplish this end for a study of the hypothetical unprotected transient overpower accident conducted for the FFTF

  11. 3m Vacuum Ultraviolet Spectrometer with Optical Multichannel Detector

    International Nuclear Information System (INIS)

    Martin, P.; Peraza, C.; Blanco, F.; Campos, J.

    1993-01-01

    This paper describes the design and the performance of a normal incidence vacuum ultraviolet spectrometer, for the 300-2400 A spectral range. It is provided with a multichannel detection system. The monochromator is original design and it has been built at CIEMAT. It is equipped with a 3 m concave holographic grating with 2400 grooves/mm. The multichannel detector consists of a windowless double microchannel plate / phosphor screen image intensifier, coupled by fiber optic to a 1024 elements self-scanning linear photodiode array. The output from the array is digitized by a 12-bit analog to digital converter and stored in a computer, for its later analysis. The necessary software to store and display data has been developed. (Author) 18 refs

  12. Hybrid-Source Impedance Networks

    DEFF Research Database (Denmark)

    Li, Ding; Gao, Feng; Loh, Poh Chiang

    2010-01-01

    Hybrid-source impedance networks have attracted attention among researchers because of their flexibility in performing buck-boost energy conversion. To date, three distinct types of impedance networks can be summarized for implementing voltage-type inverters with another three types summarized...... for current-type inverters. These impedance networks can in principle be combined into two generic network entities, before multiple of them can further be connected together by applying any of the two proposed generalized cascading concepts. The resulting two-level and three-level inverters implemented using...

  13. Multichannel interval timer

    International Nuclear Information System (INIS)

    Turko, B.T.

    1983-10-01

    A CAMAC based modular multichannel interval timer is described. The timer comprises twelve high resolution time digitizers with a common start enabling twelve independent stop inputs. Ten time ranges from 2.5 μs to 1.3 μs can be preset. Time can be read out in twelve 24-bit words either via CAMAC Crate Controller or an external FIFO register. LSB time calibration is 78.125 ps. An additional word reads out the operational status of twelve stop channels. The system consists of two modules. The analog module contains a reference clock and 13 analog time stretchers. The digital module contains counters, logic and interface circuits. The timer has an excellent differential linearity, thermal stability and crosstalk free performance

  14. Digital baseline estimation method for multi-channel pulse height analyzing

    International Nuclear Information System (INIS)

    Xiao Wuyun; Wei Yixiang; Ai Xianyun

    2005-01-01

    The basic features of digital baseline estimation for multi-channel pulse height analysis are introduced. The weight-function of minimum-noise baseline filter is deduced with functional variational calculus. The frequency response of this filter is also deduced with Fourier transformation, and the influence of parameters on amplitude frequency response characteristics is discussed. With MATLAB software, the noise voltage signal from the charge sensitive preamplifier is simulated, and the processing effect of minimum-noise digital baseline estimation is verified. According to the results of this research, digital baseline estimation method can estimate baseline optimally, and it is very suitable to be used in digital multi-channel pulse height analysis. (authors)

  15. EDMC: An enhanced distributed multi-channel anti-collision algorithm for RFID reader system

    Science.gov (United States)

    Zhang, YuJing; Cui, Yinghua

    2017-05-01

    In this paper, we proposes an enhanced distributed multi-channel reader anti-collision algorithm for RFID environments which is based on the distributed multi-channel reader anti-collision algorithm for RFID environments (called DiMCA). We proposes a monitor method to decide whether reader receive the latest control news after it selected the data channel. The simulation result shows that it improves interrogation delay.

  16. Pumping slots: impedances and power losses

    Energy Technology Data Exchange (ETDEWEB)

    Kurennoy, S [Maryland Univ., College Park, MD (United States). Dept. of Physics

    1996-08-01

    Contributions of pumping slots to the beam coupling impedances and power losses in a B-factory ring are considered. While their leading contribution is to the inductive impedance, for high-intensity machines with short bunches like e{sup +}e{sup -} B-factories the real part of the impedance and related loss factors are also important. Using an analytical approach we calculate the coupling impedances and loss factors due to slots in a ring with an arbitrary cross section of the vacuum chamber. Effects of the slot tilt on the beam impedance are also considered, and restrictions on the tilt angle are derived from limitations on the impedance increase. The power leakage through the slots is discussed briefly. The results are applied to the KEK B-factory. (author)

  17. Front-end electronics for multichannel semiconductor detector systems

    CERN Document Server

    Grybos, P

    2010-01-01

    Front-end electronics for multichannel semiconductor detektor systems Volume 08, EuCARD Editorial Series on Accelerator Science and Technology The monograph is devoted to many different aspects related to front-end electronics for semiconductor detector systems, namely: − designing and testing silicon position sensitive detectors for HEP experiments and X-ray imaging applications, − designing and testing of multichannel readout electronics for semiconductor detectors used in X-ray imaging applications, especially for noise minimization, fast signal processing, crosstalk reduction and good matching performance, − optimization of semiconductor detection systems in respect to the effects of radiation damage. The monograph is the result mainly of the author's experience in the above-mentioned areas and it is an attempt of a comprehensive presentation of issues related to the position sensitive detection system working in a single photon counting mode and intended to X-ray imaging applications. The structure...

  18. Closed-loop, multichannel experimentation using the open-source NeuroRighter electrophysiology platform

    Directory of Open Access Journals (Sweden)

    Jonathan Paul Newman

    2013-01-01

    Full Text Available Single neuron feedback control techniques, such as voltage clamp and dynamic clamp, have enabled numerous advances in our understanding of ion channels, electrochemical signaling, and neural dynamics. Although commercially available multichannel recording and stimulation systems are commonly used for studying neural processing at the network level, they provide little native support for real-time feedback. We developed the open-source NeuroRighter multichannel electrophysiology hardware and software platform for closed-loop multichannel control with a focus on accessibility and low cost. NeuroRighter allows 64 channels of stimulation and recording for around US $10,000, along with the ability to integrate with other software and hardware. Here, we present substantial enhancements to the NeuroRighter platform, including a redesigned desktop application, a new stimulation subsystem allowing arbitrary stimulation patterns, low-latency data servers for accessing data streams, and a new application programming interface (API for creating closed-loop protocols that can be inserted into NeuroRighter as plugin programs. This greatly simplifies the design of sophisticated real-time experiments without sacrificing the power and speed of a compiled programming language. Here we present a detailed description of NeuroRighter as a stand alone application, its plugin API, and an extensive set of case studies that highlight the system's abilities for conducting closed-loop, multichannel interfacing experiments.

  19. RAC-Multi: Reader Anti-Collision Algorithm for Multichannel Mobile RFID Networks

    Directory of Open Access Journals (Sweden)

    Kwangcheol Shin

    2009-12-01

    Full Text Available At present, RFID is installed on mobile devices such as mobile phones or PDAs and provides a means to obtain information about objects equipped with an RFID tag over a multi-channeled telecommunication networks. To use mobile RFIDs, reader collision problems should be addressed given that readers are continuously moving. Moreover, in a multichannel environment for mobile RFIDs, interference between adjacent channels should be considered. This work first defines a new concept of a reader collision problem between adjacent channels and then suggests a novel reader anti-collision algorithm for RFID readers that use multiple channels. To avoid interference with adjacent channels, the suggested algorithm separates data channels into odd and even numbered channels and allocates odd-numbered channels first to readers. It also sets an unused channel between the control channel and data channels to ensure that control messages and the signal of the adjacent channel experience no interference. Experimental results show that suggested algorithm shows throughput improvements ranging from 29% to 46% for tag identifications compared to the GENTLE reader anti-collision algorithm for multichannel RFID networks.

  20. Multichannel conformal blocks for scattering amplitudes

    Science.gov (United States)

    Belitsky, A. V.

    2018-05-01

    By performing resummation of small fermion-antifermion pairs within the pentagon form factor program to scattering amplitudes in planar N = 4 superYang-Mills theory, we construct multichannel conformal blocks within the flux-tube picture for N-sided NMHV polygons. This procedure is equivalent to summation of descendants of conformal primaries in the OPE framework. The resulting conformal partial waves are determined by multivariable hypergeometric series of Lauricella-Saran type.

  1. TIA model is attainable in Wistar rats by intraluminal occlusion of the MCA for 10min or shorter.

    Science.gov (United States)

    Durukan Tolvanen, A; Tatlisumak, E; Pedrono, E; Abo-Ramadan, U; Tatlisumak, T

    2017-05-15

    Transient ischemic attack (TIA) has received only little attention in the experimental research field. Recently, we introduced a TIA model for mice, and here we set similar principles for simulating this human condition in Wistar rats. In the model: 1) transient nature of the event is ensured, and 2) 24h after the event animals are free from any sensorimotor deficit and from any detectable lesion by magnetic resonance imaging (MRI). Animals experienced varying durations of ischemia (5, 10, 12.5, 15, 25, and 30min, n=6-8pergroup) by intraluminal middle cerebral artery occlusion (MCAO). Ischemia severity and reperfusion rates were controlled by cerebral blood flow measurements. Sensorimotor neurological evaluations and MRI at 24h differentiated between TIA and ischemic stroke. Hematoxylin and eosin staining and apoptotic cell counts revealed pathological correlates of the event. We found that already 12.5min of ischemia was long enough to induce ischemic stroke in Wistar rats. Ten min or shorter durations induced neither gross neurological deficits nor infarcts visible on MRI, but histologically caused selective neuronal necrosis. A separate group of animals with 10min of ischemia followed up to 1week after reperfusion remained free of infarction and any MRI signal change. Thus, 10min or shorter focal cerebral ischemia induced by intraluminal MCAO in Wistar rats provides a clinically relevant TIA the rat. This model is useful for studying molecular correlates of TIA. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Impedance and component heating

    CERN Document Server

    Métral, E; Mounet, N; Pieloni, T; Salvant, B

    2015-01-01

    The impedance is a complex function of frequency, which represents, for the plane under consideration (longitudinal, horizontal or vertical), the force integrated over the length of an element, from a “source” to a “test” wave, normalized by their charges. In general, the impedance in a given plane is a nonlinear function of the test and source transverse coordinates, but it is most of the time sufficient to consider only the first few linear terms. Impedances can influence the motion of trailing particles, in the longitudinal and in one or both transverse directions, leading to energy loss, beam instabilities, or producing undesirable secondary effects such as excessive heating of sensitive components at or near the chamber wall, called beam-induced RF heating. The LHC performance limitations linked to impedances encountered during the 2010-2012 run are reviewed and the currently expected situation during the HL-LHC era is discussed.

  3. Abdominal aortic aneurysm, arterial stiffening and the role of the intraluminal thrombus

    DEFF Research Database (Denmark)

    Lyck Hansen, Maria; Dahl Thomsen, Marie; Melholt Rasmussen, Lars

    2015-01-01

    PATIENTS AND METHODS: PWV and PWA were measured in male patients with AAA from an ongoing Danish AAA screening trial. Information on blood pressure, medications, BMI and smoking status was obtained at inclusion. RESULTS: In total, 157 patients were included. Mean age was 73 years. Mean AAA size...... was 42.2 mm. Fifty-six of the patients had an intraluminal thrombus, and patients with AAA and ILT had a significantly higher Aix75 than patients with AAA but without ILT (Mean = 28.3 ± 1.4 SEM vs. 24.9 ± 0.81, p=0.027), a difference that was also significant when adjusting for AAA size, blood pressure...... and age. There was no difference in PWV between the groups. CONCLUSIONS: Haemodynamic properties of the aorta are affected by the presence of ILT in patients with AAA that is not explained by aortic size. Alternatively, these findings could be explained by associations between ILT and properties...

  4. Note: Design and investigation of a multichannel plasma-jet triggered gas switch.

    Science.gov (United States)

    Tie, Weihao; Liu, Xuandong; Zhang, Qiaogen; Liu, Shanhong

    2014-07-01

    We described the fabrication and testing of a multichannel plasma-jet triggered gas switch (MPJTGS). A novel six-channel annular micro-plasma-gun was embedded in the trigger electrode to generate multichannel plasma jets as a nanosecond trigger pulse arrived. The gas breakdown in multiple sites of the spark gap was induced and fixed around jet orifices by the plasma jets. We tested the multichannel discharge characteristics of the MPJTGS in two working modes with charge voltage of 50 kV, trigger voltage of +40 kV (25 ns rise time), and trigger energy of 240 J, 32 J, and 2 J, respectively, at different working coefficients. Results show that the average number of discharge channels increased as the trigger energy increased, and decreased as the working coefficient decreased. At a working coefficient of 87.1% and trigger energy of 240 J, the average number of discharge channels in Mode II could reach 4.1.

  5. Software filtering method to suppress spike pulse interference in multi-channel scaler

    International Nuclear Information System (INIS)

    Huang Shun; Zhao Xiuliang; Li Zhiqiang; Zhao Yanhui

    2008-01-01

    In the test on anti-jamming function of a multi-channel scaler, we found that the spike pulse interference on the second level counter caused by the motor start-stop operations brings a major count error. There are resolvable characteristics between effective signal and spike pulse interference, and multi-channel hardware filtering circuit is too huge and can't filter thoroughly, therefore we designed a software filtering method. In this method based on C8051F020 MCU, we dynamically store sampling values of one channel in only a one-byte variable and distinguish the rise-trail edge of a signal and spike pulse interference because of value changes of the variable. Test showed that the filtering software method can solve the error counting problem of the multi-channel scaler caused by the motor start-stop operations. The flow chart and source codes of the method were detailed in this paper. (authors)

  6. Short-circuit impedance measurement

    DEFF Research Database (Denmark)

    Pedersen, Knud Ole Helgesen; Nielsen, Arne Hejde; Poulsen, Niels Kjølstad

    2003-01-01

    Methods for estimating the short-circuit impedance in the power grid are investigated for various voltage levels and situations. The short-circuit impedance is measured, preferably from naturally occurring load changes in the grid, and it is shown that such a measurement system faces different...

  7. Multichannel perimetric alterations in systemic lupus erythematosus treated with hydroxychloroquine.

    Science.gov (United States)

    Piñero, David P; Monllor, Begoña; Camps, Vicente J; de Fez, Dolores

    Systemic lupus erythematosus (SLE) is a multiorgan autoimmune disease of unknown etiology with many clinical manifestations. We report the first case of SLE in which visual alterations were evaluated with multichannel perimetry. Some achromatic and color vision alterations may be present in SLE, especially when treated with hydroxychloroquine. The sensitivity losses detected in the chromatic channels in the central zone of the visual field were consistent with the results of the FM 100 Hue color test. Likewise, the multichannel perimetry detected sensitivity losses in the parafoveal area for both chromatic channels, especially for the blue-yellow. Copyright © 2016 Spanish General Council of Optometry. Published by Elsevier España, S.L.U. All rights reserved.

  8. Impedance Based Analysis and Design of Harmonic Resonant Controller for a Wide Range of Grid Impedance

    DEFF Research Database (Denmark)

    Kwon, Jun Bum; Wang, Xiongfei; Blaabjerg, Frede

    2014-01-01

    This paper investigates the effect of grid impedance variation on harmonic resonant current controllers for gridconnected voltage source converters by means of impedance-based analysis. It reveals that the negative harmonic resistances tend to be derived from harmonic resonant controllers...... in the closed-loop output admittance of converter. Such negative resistances may interact with the grid impedance resulting in steady state error or unstable harmonic compensation. To deal with this problem, a design guideline for harmonic resonant controllers under a wide range of grid impedance is proposed...

  9. Efficient Numerical Solution of Coupled Radial Differential Equations in Multichannel Scattering Problems

    International Nuclear Information System (INIS)

    Houfek, Karel

    2008-01-01

    Numerical solution of coupled radial differential equations which are encountered in multichannel scattering problems is presented. Numerical approach is based on the combination of the exterior complex scaling method and the finite-elements method with the discrete variable representation. This method can be used not only to solve multichannel scattering problem but also to find bound states and resonance positions and widths directly by diagonalization of the corresponding complex scaled Hamiltonian. Efficiency and accuracy of this method is demonstrated on an analytically solvable two-channel problem.

  10. The design and implementation of a PC based multi-channel scaler system

    International Nuclear Information System (INIS)

    Wang Qiang; Chinese Academy of Sciences, Beijing; Jin Dapeng; Liu Zhen'an; Zhao Dixin

    2007-01-01

    A multi-channel scaler system is designed for the system check and status monitoring of the BESIII trigger system. It is composed of a PC, two PCI interface multi-channel scaler cards, the corresponding drivers and user programs. Total 64 signals can be scaled and monitored in real time. The scaled data are recorded locally and some of them are distributed to the online system. In this paper, the hardware structure, software development and long time running stability of the system are introduced. (authors)

  11. Disorder-induced topological transitions in multichannel Majorana wires

    NARCIS (Netherlands)

    Pekerten, B.; Teker, A.; Bozat, Ö.; Wimmer, M.T.; Adagideli, I

    2017-01-01

    In this work, we investigate the effect of disorder on the topological properties of multichannel superconductor nanowires. While the standard expectation is that the spectral gap is closed and opened at transitions that change the topological index of the wire, we show that the closing and

  12. The Art of Multi-channel Hypermedia Application Development

    NARCIS (Netherlands)

    Synodinos, Dionysios G.; Avgeriou, Paris

    2003-01-01

    The plethora of networked devices and platforms that continuously come to light, as well as the emergence of alternative ways to access the internet, have increased the demand for multi-channel access to hypermedia applications. Researchers and practitioners nowadays not only have to deal with the

  13. Absence of effect of nasal continuous positive airway pressure on the esophageal phase of nutritive swallowing in newborn lambs.

    Science.gov (United States)

    Djeddi, Djamal; Cantin, Danny; Samson, Nathalie; Tian, Hao; Praud, Jean-Paul

    2013-08-01

    It is presently recommended that oral feeding be started in premature infants as soon as possible, often at an age at which nasal continuous positive airway pressure (nCPAP) is still required for ventilatory support. Our previous data showed that application of nCPAP up to 10 cmH2O in full-term lambs had no deleterious effect on cardiorespiratory safety, feeding efficiency, or on nutritive swallowing-breathing coordination. Besides fear of swallowing-breathing coordination disturbances, esophageal motility disruption by nCPAP could be a reason to delay oral feeding. To our knowledge, no study has focused on the effects of nCPAP on esophageal motility in the neonatal period. The aim of the present study was therefore to further assess the effects of nCPAP on oral feeding by assessing its effects on the esophageal phase of nutritive swallowing (nutritive esophagodeglutition). Six full-term lambs, ages 2 to 3 days, underwent esophageal multichannel intraluminal impedance-pH monitoring. Lambs were bottle-fed under 2 randomized conditions, namely spontaneous breathing and nCPAP 6 cmH(2)O. Beyond confirmation of unaltered feeding efficiency, analysis of multiple variables measured by impedance monitoring revealed that nCPAP 6 does not alter nutritive esophagodeglutition in any way (nCPAP vs spontaneous breathing, P > 0.1 for all variables). offering further support to neonatologists pleading for initiation of oral feeding in infants still on nCPAP, the present results set the foundations for similar clinical studies in preterm human infants to confirm the absence of effects of nCPAP on nutritive swallowing.

  14. Multi-channel near infrared spectroradiometer

    International Nuclear Information System (INIS)

    Joseph, G.B.; Biddles, B.J.; D'silva, R.A.; Picot, A.J.; Ackerman, M.J.

    1988-01-01

    A multichannel spectroradiometer has been developed by Sira Ltd. for the study of rapidly varying events in the near infrared. The instrument is being used in the examination of gun flashes, rocket motor exhaust efflux analysis and ordnance or pyrotechnic flash studies. The spectral range of about 1.4 to 5.2 microns is covered in two bands with the first order dispersion from a pair of ruled blazed gratings being imaged onto a pair of detector arrays. Data may be logged at a rate of 1000 complete spectra per second

  15. Superconducting fault current-limiter with variable shunt impedance

    Science.gov (United States)

    Llambes, Juan Carlos H; Xiong, Xuming

    2013-11-19

    A superconducting fault current-limiter is provided, including a superconducting element configured to resistively or inductively limit a fault current, and one or more variable-impedance shunts electrically coupled in parallel with the superconducting element. The variable-impedance shunt(s) is configured to present a first impedance during a superconducting state of the superconducting element and a second impedance during a normal resistive state of the superconducting element. The superconducting element transitions from the superconducting state to the normal resistive state responsive to the fault current, and responsive thereto, the variable-impedance shunt(s) transitions from the first to the second impedance. The second impedance of the variable-impedance shunt(s) is a lower impedance than the first impedance, which facilitates current flow through the variable-impedance shunt(s) during a recovery transition of the superconducting element from the normal resistive state to the superconducting state, and thus, facilitates recovery of the superconducting element under load.

  16. Rf Discharge Impedance Measurements Using a New Method to Determine the Stray Impedances

    NARCIS (Netherlands)

    Bakker, L.P.; Kroesen, G.M.W.; Hoog, de F.J.

    1999-01-01

    The impedance of a capacitively coupled radio frequency discharge in a tubular fluorescent lamp filled with neon and mercury is measured. The stray impedances in the electrical network are determined using a new method that requires no extra instruments. The reflection of power is used to determine

  17. Multichannel signal enhancement using a remote wireless microphone

    NARCIS (Netherlands)

    Bloemendal, Brian; Van De Laar, Jakob; Sommen, Piet

    2012-01-01

    A novel approach to multichannel signal enhancement is presented that exploits data from a remote wireless microphone (RWM). This RWM is placed near an interfering source and transmits only autocorrelation data of its observations to a host, i.e., not the entire signal. The host has access to the

  18. Impedance of a nanoantenna

    International Nuclear Information System (INIS)

    Greffet, Jean-Jacques; Laroche, Marine; Marquier, Francois

    2009-01-01

    We introduce a generalized definition of the impedance of a nanoantenna that can be applied to any system. We also introduce a definition of the impedance of a two level system. Using this framework, we establish a link between the electrical engineering and the quantum optics picture of light emission.

  19. Classification of Multichannel ECG Signals Using a Cross-Distance Analysis

    National Research Council Canada - National Science Library

    Shahram, Morteza

    2001-01-01

    This paper presents a multi-stage algorithm for multi-channel ECG beat classification into normal and abnormal categories using a sequential beat clustering and a cross- distance analysis algorithm...

  20. Multi-channel electronically scanned cryogenic pressure sensor

    Science.gov (United States)

    Chapman, John J. (Inventor); Hopson, Purnell, Jr. (Inventor); Kruse, Nancy M. H. (Inventor)

    1995-01-01

    A miniature, multi-channel, electronically scanned pressure measuring device uses electrostatically bonded silicon dies in a multielement array. These dies are bonded at specific sites on a glass, prepatterned substrate. Thermal data is multiplexed and recorded on each individual pressure measuring diaphragm. The device functions in a cryogenic environment without the need of heaters to keep the sensor at constant temperatures.

  1. AN ADAPTIVE MULTI-CHANNEL SPECTROELLIPSOMETER FOR ECOLOGICAL MONITORING

    Directory of Open Access Journals (Sweden)

    F. A. Mkrtchyan

    2012-09-01

    Full Text Available The creation of multichannel polarization optical instrumentation and use of spectroellipsometric technology are very important for the real-time ecological control of aquatic environment. Spectroellipsometric devices give us high precision of measurements. This report is aimed to describe: •A technology of combined use of spectroellipsometry and algorithms of identification and recognition that allowed the creation of a standard integral complex of instrumental, algorithmic, modular and software tools for the collection and processing of data on the aquatic environment quality with forecasting and decision - making functions. •A compact measuring - information multichannel spectroellipsometric system (device for monitoring the quality of aquatic environment, that is based on the combined use of spectroellipsometry and training, classification, and identification algorithms. This spectroellipsometric system will differ from modern foreign analogues by the use of a new and very promising method of ellipsometric measurements, an original element base of polarization optics and a complex mathematical approach to estimating the quality of a water object subjected to anthropogenic influence.Unlike foreign analogues, the system has no rotating polarization elements. This allows one to increase the signal-to-noise ratio and the long-term stability of measurements, to simplify and reduce the price of multichannel spectroellipsometers. The system will be trainable to the recognition of the pollutants of aquatic environment. A spectroellipsometer in laboratories of V.A. Kotelnikov's Institute of Radioengineering and Electronics, Russian Academy of Sciences is designed for in-situ real time measurements of spectra of ellipsometric parameters Psi and Delta with consequent changeover to spectra of transmitted and reflected signal from water media in frames of used physical model of water environment.

  2. Simulation study on vertically distributed multi-channel tangential interferometry for KSTAR

    International Nuclear Information System (INIS)

    Nam, Y U; Juhn, J W

    2012-01-01

    Interferometry is powerful and reliable diagnostics which measures line-integrated electron density. Since this technique only measures an averaged value over whole probing line, a multi-channel scheme is used for an analysis for spatial distribution and variation of electron density. Typical setups of the multi-channel measurement are schemes of radially distributed vertical lines, vertically distributed horizontal lines and horizontally distributed tangential lines. In Korea Superconducting Tokamak Advanced Research, a vertically distributed multi-channel tangential interferometry is planned instead of above typical schemes due to limitation of complex in-vessel geometry and narrow diagnostics port through cryostat. Total 5-channels will be vertically placed as symmetric with the mid-plain. One of the characteristic features of the vertically distributed channels is that each channel is viewing different poloidal angle, while the horizontally distributed channels are viewing different toroidal angle. This scheme also can be used on an investigation of the up-down asymmetry and the vertical oscillation of plasma. Simulation has been performed and the result will be discussed to verify the possibility and the estimated effectiveness of the scheme on this paper.

  3. Cascaded impedance networks for NPC inverter

    DEFF Research Database (Denmark)

    Li, Ding; Gao, Feng; Loh, Poh Chiang

    2010-01-01

    they are subject to the renewable sources. To date, three distinct types of impedance networks can be summarized for implementing a hybrid source impedance network, which can in principle be combined and cascaded before connected to a NPC inverter by proposed two ways. The resulting cascaded impedance network NPC...

  4. Impedance of finite length resistive cylinder

    Directory of Open Access Journals (Sweden)

    S. Krinsky

    2004-11-01

    Full Text Available We determine the impedance of a cylindrical metal tube (resistor of radius a, length g, and conductivity σ attached at each end to perfect conductors of semi-infinite length. Our main interest is in the asymptotic behavior of the impedance at high frequency (k≫1/a. In the equilibrium regime, ka^{2}≪g, the impedance per unit length is accurately described by the well-known result for an infinite length tube with conductivity σ. In the transient regime, ka^{2}≫g, where the contribution of transition radiation arising from the discontinuity in conductivity is important, we derive an analytic expression for the impedance and compute the short-range wakefield. The analytic results are shown to agree with numerical evaluation of the impedance.

  5. A high-speed interface for multi-channel analyzer

    International Nuclear Information System (INIS)

    Shen Ji; Zheng Zhong; Qiao Chong; Chen Ziyu; Ye Yunxiu; Ye Zhenyu

    2003-01-01

    This paper presents a high-speed computer interface for multi-channel analyzer based on DMA technique. Its essential principle and operating procedure are introduced. By the detecting of γ spectrum of 137 Cs with the interface, it's proved that the interface can meet the requirements of high-speed data acquisition

  6. Compact multichannel MEMS based spectrometer for FBG sensing

    DEFF Research Database (Denmark)

    Ganziy, Denis; Rose, Bjarke; Bang, Ole

    2017-01-01

    We propose a novel type of compact multichannel MEMS based spectrometer, where we replace the linear detector with a Digital Micromirror Device (DMD). The DMD is typically cheaper and has better pixel sampling than an InGaAs detector used in the 1550 nm range, which leads to cost reduction...

  7. A lossless multichannel bio-signal compression based on low-complexity joint coding scheme for portable medical devices.

    Science.gov (United States)

    Kim, Dong-Sun; Kwon, Jin-San

    2014-09-18

    Research on real-time health systems have received great attention during recent years and the needs of high-quality personal multichannel medical signal compression for personal medical product applications are increasing. The international MPEG-4 audio lossless coding (ALS) standard supports a joint channel-coding scheme for improving compression performance of multichannel signals and it is very efficient compression method for multi-channel biosignals. However, the computational complexity of such a multichannel coding scheme is significantly greater than that of other lossless audio encoders. In this paper, we present a multichannel hardware encoder based on a low-complexity joint-coding technique and shared multiplier scheme for portable devices. A joint-coding decision method and a reference channel selection scheme are modified for a low-complexity joint coder. The proposed joint coding decision method determines the optimized joint-coding operation based on the relationship between the cross correlation of residual signals and the compression ratio. The reference channel selection is designed to select a channel for the entropy coding of the joint coding. The hardware encoder operates at a 40 MHz clock frequency and supports two-channel parallel encoding for the multichannel monitoring system. Experimental results show that the compression ratio increases by 0.06%, whereas the computational complexity decreases by 20.72% compared to the MPEG-4 ALS reference software encoder. In addition, the compression ratio increases by about 11.92%, compared to the single channel based bio-signal lossless data compressor.

  8. Multiple scattering theory for non-local and multichannel potentials

    Czech Academy of Sciences Publication Activity Database

    Natoli, C.R.; Krüger, P.; Hatada, K.; Hayakawa, K.; Sébilleau, D.; Šipr, Ondřej

    2012-01-01

    Roč. 24, č. 36 (2012), s. 1-20 ISSN 0953-8984 Institutional research plan: CEZ:AV0Z10100521 Keywords : multichannel scattering * correlation s * density matrix Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.355, year: 2012

  9. Multichannel optical mapping: investigation of depth information

    Science.gov (United States)

    Sase, Ichiro; Eda, Hideo; Seiyama, Akitoshi; Tanabe, Hiroki C.; Takatsuki, Akira; Yanagida, Toshio

    2001-06-01

    Near infrared (NIR) light has become a powerful tool for non-invasive imaging of human brain activity. Many systems have been developed to capture the changes in regional brain blood flow and hemoglobin oxygenation, which occur in the human cortex in response to neural activity. We have developed a multi-channel reflectance imaging system, which can be used as a `mapping device' and also as a `multi-channel spectrophotometer'. In the present study, we visualized changes in the hemodynamics of the human occipital region in multiple ways. (1) Stimulating left and right primary visual cortex independently by showing sector shaped checkerboards sequentially over the contralateral visual field, resulted in corresponding changes in the hemodynamics observed by `mapping' measurement. (2) Simultaneous measurement of functional-MRI and NIR (changes in total hemoglobin) during visual stimulation showed good spatial and temporal correlation with each other. (3) Placing multiple channels densely over the occipital region demonstrated spatial patterns more precisely, and depth information was also acquired by placing each pair of illumination and detection fibers at various distances. These results indicate that optical method can provide data for 3D analysis of human brain functions.

  10. Dosimetric evaluation of a novel high dose rate (HDR) intraluminal / interstitial brachytherapy applicator for gastrointestinal and bladder cancers

    Science.gov (United States)

    Aghamiri, Seyyed Mahmoud Reza; Najarian, Siamak; Jaberi, Ramin

    2010-01-01

    High dose rate (HDR) brachytherapy is one of the accepted treatment modalities in gastro‐intestinal tract and bladder carcinomas. Considering the shortcoming of contact brachytherapy routinely used in gastrointestinal tract in treatment of big tumors or invasive method of bladder treatment, an intraluminal applicator with the capability of insertion into the tumor depth seems to be useful. This study presents some dosimetric evaluations to introduce this applicator to the clinical use. The radiation attenuation characteristics of the applicator were evaluated by means of two dosimetric methods including well‐type chamber and radiochromic film. The proposed 110 cm long applicator has a flexible structure made of stainless steel for easy passage through lumens and a needle tip to drill into big tumors. The 2 mm diameter of the applicator is thick enough for source transition, while easy passage through any narrow lumen such as endoscope or cystoscope working channel is ensured. Well‐chamber results showed an acceptably low attenuation of this steel springy applicator. Performing absolute dosimetry resulted in a correlation coefficient of R=0.9916(p‐value≈10−7) between standard interstitial applicator and the one proposed in this article. This study not only introduces a novel applicator with acceptable attenuation but also proves the response independency of the GAFCHROMIC EBT films to energy. By applying the dose response of the applicator in the treatment planning software, it can be used as a new intraluminal / interstitial applicator. PACS number: 87.53.Bn, 87.53.Jw, 29.40.Cs

  11. Tracking of electrochemical impedance of batteries

    Science.gov (United States)

    Piret, H.; Granjon, P.; Guillet, N.; Cattin, V.

    2016-04-01

    This paper presents an evolutionary battery impedance estimation method, which can be easily embedded in vehicles or nomad devices. The proposed method not only allows an accurate frequency impedance estimation, but also a tracking of its temporal evolution contrary to classical electrochemical impedance spectroscopy methods. Taking into account constraints of cost and complexity, we propose to use the existing electronics of current control to perform a frequency evolutionary estimation of the electrochemical impedance. The developed method uses a simple wideband input signal, and relies on a recursive local average of Fourier transforms. The averaging is controlled by a single parameter, managing a trade-off between tracking and estimation performance. This normalized parameter allows to correctly adapt the behavior of the proposed estimator to the variations of the impedance. The advantage of the proposed method is twofold: the method is easy to embed into a simple electronic circuit, and the battery impedance estimator is evolutionary. The ability of the method to monitor the impedance over time is demonstrated on a simulator, and on a real Lithium ion battery, on which a repeatability study is carried out. The experiments reveal good tracking results, and estimation performance as accurate as the usual laboratory approaches.

  12. Behind the web store: the organisational and spatial evolution of multichannel retailing in Toronto

    OpenAIRE

    Andrew Currah

    2002-01-01

    In this paper I address two issues of general relevance to contemporary debates in economic geography: first, the organisational and spatial implications of new information technologies for the economic landscape; and, second, the enduring role of place to digital capitalism. Specifically, I examine the organisational evolution of multichannel retailing in Toronto from a geographical perspective. Bricks-and-mortar retailers are increasingly pursuing a multichannel strategy by operating an Int...

  13. Investigation and management of gastro-oesophageal reflux in United Kingdom neonatal intensive care units.

    Science.gov (United States)

    Rossor, Thomas; Andradi, Gwendolyn; Bhat, Ravindra; Greenough, Anne

    2018-01-01

    In 2004, wide variation in the investigation and management of gastro-oesophageal reflux (GOR) of infants on UK major neonatal units was demonstrated. Our aim was to resurvey neonatal practitioners to determine current practice and whether it was now evidence based. A questionnaire was sent to all 207 UK neonatal units. Responses were obtained from 84% of units. The most frequent 'investigation' was a trial of therapy (83% of units); pH studies were used in 38%, upper GI contrast studies in 19% and multichannel intraluminal impedance (MII)/pH studies in 5%. Only six units suggested a threshold for an abnormal pH study and two units for an abnormal MII study. Infants were commenced on antireflux medication without investigation always in 32% of units, often in 29%, occasionally in 19% and only never in 1%. Gaviscon was used as first line treatment in 60% of units, and other medications included ranitidine in 53%, thickening agents in 27%, proton pump inhibitors in 23%, domperidone in 22% and erythromycin in 6%. There remains a wide variation in diagnostic and treatment strategies for infants with suspected GOR on neonatal intensive care units, emphasising the need for randomised trials to determine appropriate GOR management. ©2017 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  14. RHIC injection kicker impedance

    International Nuclear Information System (INIS)

    Mane, V.; Peggs, S.; Trbojevic, D.; Zhang, W.

    1995-01-01

    The longitudinal impedance of the RHIC injection kicker is measured using the wire method up to a frequency of 3 GHz. The mismatch between the 50 ohm cable and the wire and pipe system is calibrated using the TRL calibration algorithm. Various methods of reducing the impedance, such as coated ceramic pipe and copper strips are investigated

  15. Retail business model transformation in multichannel environment

    OpenAIRE

    Chapagain, B. (Bimala)

    2015-01-01

    Abstract With the advent of internet and e-commerce, the way of carrying out business and transactions has changed to a great extent. Consumers are continuously changing the way they do shopping and this has forced retail business to transform their traditional brick and mortar into adopting multi-channel business models. Retailing is one of the most dynamic and competitive areas of business organization. Effective marketin...

  16. E-Fulfillment and Multi-Channel Distribution – A Review

    NARCIS (Netherlands)

    N.A.H. Agatz (Niels); M. Fleischmann (Moritz); J.A.E.E. van Nunen (Jo)

    2006-01-01

    textabstractThis review addresses the specific supply chain management issues of Internet fulfillment in a multi-channel environment. It provides a systematic overview of managerial planning tasks and reviews corresponding quantitative models. In this way, we aim to enhance the understanding of

  17. On iteration-separable method on the multichannel scattering theory

    International Nuclear Information System (INIS)

    Zubarev, A.L.; Ivlieva, I.N.; Podkopaev, A.P.

    1975-01-01

    The iteration-separable method for solving the equations of the Lippman-Schwinger type is suggested. Exponential convergency of the method of proven. Numerical convergency is clarified on the e + H scattering. Application of the method to the theory of multichannel scattering is formulated

  18. A multi-channel coronal spectrophotometer.

    Science.gov (United States)

    Landman, D. A.; Orrall, F. Q.; Zane, R.

    1973-01-01

    We describe a new multi-channel coronal spectrophotometer system, presently being installed at Mees Solar Observatory, Mount Haleakala, Maui. The apparatus is designed to record and interpret intensities from many sections of the visible and near-visible spectral regions simultaneously, with relatively high spatial and temporal resolution. The detector, a thermoelectrically cooled silicon vidicon camera tube, has its central target area divided into a rectangular array of about 100,000 pixels and is read out in a slow-scan (about 2 sec/frame) mode. Instrument functioning is entirely under PDP 11/45 computer control, and interfacing is via the CAMAC system.

  19. Onze anos de experiência com emprego do anel intraluminal para tratamento das doenças da aorta

    Directory of Open Access Journals (Sweden)

    BERNARDES Rodrigo de Castro

    1999-01-01

    Full Text Available O tratamento cirúrgico das doenças da aorta é geralmente acompanhado de altas taxas de morbimortalidade. O paciente que tem média de idade avançada geralmente é apresentado ao cirurgião em estado grave, com má condição nutricional, muitas vezes com alterações em vários órgãos e sistemas causados pela própria doença aguda. A correção convencional exige técnicas coadjuvantes complexas e agressivas como a circulação extracorpórea prolongada, hipotermia profunda, parada circulatória total além de prolongados tempos de pinçamento de aorta. Na tentativa de reduzir a agressão cirúrgica no paciente já intensamente debilitado pela própria doença, desenvolvemos, em 1988, um anel intraluminal (1, 2 que tem medidas projetadas e experimentadas para facilitar a sua manipulação e anastomose, proporcionando uma diminuição acentuada no tempo de operação, tempo de CEC, tempo de pinçamento de aorta, excluindo muitas vezes a circulação extracorpórea e a hipotermia, obtendo uma anastomose fácil, rápida, segura e hemostática. Entre março de 1988 e janeiro de 1999, 432 pacientes foram submetidos a tratamento cirúrgico de dissecções ou aneurismas da aorta em nosso Serviço. Em 328 pacientes empregamos o anel intraluminal como técnica de anastomose. Usamos 489 anéis. Cento e vinte e cinco pacientes eram portadores de dissecção aguda de aorta do tipo A, 29 eram portadores de dissecção aguda de aorta do tipo B, 81 de aneurisma de aorta ascendente, 8 de aneurisma de arco aórtico, 28 pacientes eram portadores de aneurisma de aorta torácica descendente, 17 eram portadores de aneurisma toracoabdominal e 40 pacientes de aneurisma de aorta abdominal infra-renal. A mortalidade global foi de 13,41%. O seguimento ambulatorial destes pacientes variou de 11 anos a 25 dias. A curva actuarial de sobrevivência em 11 anos mostra 67,3%. Em nenhum caso observamos as complicações descritas na literatura, como embolia, formação de

  20. Concentric artificial impedance surface for directional sound beamforming

    Directory of Open Access Journals (Sweden)

    Kyungjun Song

    2017-03-01

    Full Text Available Utilizing acoustic metasurfaces consisting of subwavelength resonant textures, we design an artificial impedance surface by creating a new boundary condition. We demonstrate a circular artificial impedance surface with surface impedance modulation for directional sound beamforming in three-dimensional space. This artificial impedance surface is implemented by revolving two-dimensional Helmholtz resonators with varying internal coiled path. Physically, the textured surface has inductive surface impedance on its inner circular patterns and capacitive surface impedance on its outer circular patterns. Directional receive beamforming can be achieved using an omnidirectional microphone located at the focal point formed by the gradient-impeding surface. In addition, the uniaxial surface impedance patterning inside the circular aperture can be used for steering the direction of the main lobe of the radiation pattern.

  1. Tapping mode microwave impedance microscopy

    KAUST Repository

    Lai, K.; Kundhikanjana, W.; Peng, H.; Cui, Y.; Kelly, M. A.; Shen, Z. X.

    2009-01-01

    We report tapping mode microwave impedance imaging based on atomic force microscope platforms. The shielded cantilever probe is critical to localize the tip-sample interaction near the tip apex. The modulated tip-sample impedance can be accurately

  2. Fibercore AstroGain fiber: multichannel erbium doped fibers for optical space communications

    Science.gov (United States)

    Hill, Mark; Gray, Rebecca; Hankey, Judith; Gillooly, Andy

    2014-03-01

    Fibercore have developed AstroGainTM fiber optimized for multichannel amplifiers used in optical satellite communications and control. The fiber has been designed to take full advantage of the photo-annealing effect that results from pumping in the 980nm region. The proprietary trivalent structure of the core matrix allows optimum recovery following radiation damage to the fiber, whilst also providing a market leading Erbium Doped Fiber Amplifier (EDFA) efficiency. Direct measurements have been taken of amplifier efficiency in a multichannel assembly, which show an effective photo-annealing recovery of up to 100% of the radiation induced attenuation through excitation of point defects.

  3. Hipotiroidismo congénito y diafragma intraluminal no fenestrado. Rara asociación

    Directory of Open Access Journals (Sweden)

    Nuvia Súarez García

    2014-02-01

    Full Text Available El hipotiroidismo congénito afecta a 1 de cada 3000 a 4000 neonatos y es una de las causas prevenibles de dificultades en el aprendizaje. Se presenta el caso de un recién nacido sexo masculino, que al nacer desarrolló síndrome de distréss respiratorio e intolerancia digestiva que progresó a la disfunción con distensión abdominal, además de signos dismórficos al examen físico. Se concluye el caso como hipotiroidismo congénito asociado a atresia duodenal por diafragma intraluminal no fenestrado. Se realizó intervención quirúrgica a las 46 horas de vida y en su posterior evolución presentó complicaciones mayores hasta fallecer. Se realizó una revisión actualizada sobre estas enfermedades en el período neonatal y se presentaron fotos del caso previo consentimiento familiar.

  4. Phase sensitive multichannel OCT

    International Nuclear Information System (INIS)

    Trasischker, W.

    2015-01-01

    The main aim of this thesis was to develop and improve phase sensitive, multichannel methods for optical coherence tomography (OCT) using light in the 840 nm and 1040 nm regime. Conventional OCT provides purely structural information by illuminating the sample by one beam and recording the backscattered signal with one detection channel. Combination of this approach with a raster scan enables the acquisition of 2D and 3D structural information with a resolution in the micrometer regime. However, sometimes additional image contrast or information is desired. Amongst other approaches, this can be provided by a phase sensitive analysis of the interference pattern. Combining phase sensitivity with the illumination of the sample by more than one beam and/or by recording the data using more than one data acquisition channel allows for even more enhanced imaging. While phase sensitive OCT gives access to additional contrast and information, multichannel OCT can provide higher imaging speed, scan eld size and exible dierential measurements. Amongst the dierential, phase sensitive approaches, Doppler OCT (DOCT) and polarization sensitive OCT (PS-OCT) are two of the most promising OCT modalities. While the former targets information on the movement of backscattering particles, the latter measures alterations of the polarization state of the light induced by the sample. Both techniques provide additional image contrast and are, due to the non-invasive and fast character of OCT, well suited for in vivo imaging of the human eye. In the course of this thesis, two dierent multichannel, phase sensitive OCT systems will be presented. First, a D-OCT system with three dierent sampling beams is described. With a central wavelength of 840 nm these three beams are emitted by three individual laser sources. This eectively eliminates any cross talk and provides the full depth range for each channel. Furthermore, by illuminating the sample from three dierent directions, the absolute

  5. Electrical impedance spectroscopy (EIS)-based evaluation of biological tissue phantoms to study multifrequency electrical impedance tomography (Mf-EIT) systems

    KAUST Repository

    Bera, Tushar Kanti

    2016-03-18

    Abstract: Electrical impedance tomography (EIT) phantoms are essential for the calibration, comparison and evaluation of the EIT systems. In EIT, the practical phantoms are typically developed based on inhomogeneities surrounded by a homogeneous background to simulate a suitable conductivity contrast. In multifrequency EIT (Mf-EIT) evaluation, the phantoms must be developed with the materials which have recognizable or distinguishable impedance variations over a wide range of frequencies. In this direction the impedance responses of the saline solution (background) and a number vegetable and fruit tissues (inhomogeneities) are studied with electrical impedance spectroscopy (EIS) and the frequency responses of bioelectrical impedance and conductivity are analyzed. A number of practical phantoms with different tissue inhomogeneities and different inhomogeneity configurations are developed and the multifrequency impedance imaging is studied with the Mf-EIT system to evaluate the phantoms. The conductivity of the vegetable inhomogeneities reconstructed from the EIT imaging is compared with the conductivity values obtained from the EIS studies. Experimental results obtained from multifrequency EIT reconstruction demonstrate that the electrical impedance of all the biological tissues inhomogenity decreases with frequency. The potato tissue phantom produces better impedance image in high frequency ranges compared to the cucumber phantom, because the cucumber impedance at high frequency becomes lesser than that of the potato at the same frequency range. Graphical Abstract: [Figure not available: see fulltext.] © 2016 The Visualization Society of Japan

  6. A fully algebraic solution for multichannel scattering of neutrons from nuclei

    International Nuclear Information System (INIS)

    Amos, K.

    2001-01-01

    In this report I give the prescription by which an algebraic solution can be found for multichannel scattering of neutrons from nuclei. The theory, developed by the Padova group, is built upon the work of Rawitscher and Delic. The approach is predicated upon finite rank representations of realistic interaction potentials and the properties of scattering matrices for separable Schrodinger interactions. The Padova approach starts with a solvable auxiliary Sturmian function (Weinberg state) problem from which a first generation set of Sturmians are defined. That basis set is formed by choosing a solvable problem at a fixed negative energy, and thereby those Sturmians can be specified in closed analytic form. Second generation Sturmians built upon the interaction potential matrices for a multichannel scattering problem of interest then can be found as linear combinations of the first generation set. The expansion coefficients result from a matrix diagonalization process. The scheme enables an expansion (usually truncated to finite rank for convenience) of the interaction potential in terms of those second generation Sturmians and in the form of a sum of separable interactions. The analytic properties of the scattering matrix from a separable Schroedinger potential gives the means by which a full algebraic solution of the multichannel scattering problem can be realized. (author)

  7. A multi-channel high-resolution time recorder system

    International Nuclear Information System (INIS)

    Zhang Lingyun; Yang Xiaojun; Song Kezhu; Wang Yanfang

    2004-01-01

    This paper introduces a multi-channel and high-speed time recorder system, which was originally designed to work in the experiments of quantum cryptography research. The novelty of the system is that all the hardware logic is performed by only one FPGA. The system can achieve several desirable features, such as simplicity, high resolution and high processing speed. (authors)

  8. Effect of flow rate distribution at the inlet on hydrodynamic mixing in narrow rectangular multi-channel

    International Nuclear Information System (INIS)

    Xu Jianjun; Chen Bingde; Wang Xiaojun

    2008-01-01

    Flow and heat transfer in the narrow rectangular multi-channel is widely en- countered in the engineering application, hydrodynamic mixing in the narrow rectangular multi-channel is one of the important concerns. With the help of the Computational Fluid Dynamics code CFX, the effect of flow rate distribution of the main channel at the inlet on hydrodynamic mixing in the narrow rectangular multi-channel is numerical simulated. The results show that the flow rate distributions at the inlet have a great effect on hydrodynamics mixing in multi-channel, the flow rate in the main channel doesn't change with increasing the axial mixing section when the average flow rate at the inlet is set. Hydrodynamic mixing will arise in the mixing section when the different ratio of the flow rate distribution at the inlet is set, and hydrodynamic mixing increases with the difference of the flow rate distribution at the inlet increase. The trend of the flow rate distribution of the main channel is consistent during the whole axial mixing section, and hydrodynamic mixing in former 4 mixing section is obvious. (authors)

  9. Fractional Order Element Based Impedance Matching

    KAUST Repository

    Radwan, Ahmed Gomaa

    2014-06-24

    Disclosed are various embodiments of methods and systems related to fractional order element based impedance matching. In one embodiment, a method includes aligning a traditional Smith chart (|.alpha.|=1) with a fractional order Smith chart (|.alpha.|.noteq.1). A load impedance is located on the traditional Smith chart and projected onto the fractional order Smith chart. A fractional order matching element is determined by transitioning along a matching circle of the fractional order Smith chart based at least in part upon characteristic line impedance. In another embodiment, a system includes a fractional order impedance matching application executed in a computing device. The fractional order impedance matching application includes logic that obtains a first set of Smith chart coordinates at a first order, determines a second set of Smith chart coordinates at a second order, and determines a fractional order matching element from the second set of Smith chart coordinates.

  10. Electrical impedance spectroscopy (EIS)-based evaluation of biological tissue phantoms to study multifrequency electrical impedance tomography (Mf-EIT) systems

    KAUST Repository

    Bera, Tushar Kanti; Nagaraju, J.; Lubineau, Gilles

    2016-01-01

    . In this direction the impedance responses of the saline solution (background) and a number vegetable and fruit tissues (inhomogeneities) are studied with electrical impedance spectroscopy (EIS) and the frequency responses of bioelectrical impedance and conductivity

  11. Robust, highly customizable, and economical multi-channel electrode for chronic multi-unit recording in behaving animals.

    Science.gov (United States)

    Tateyama, Yukina; Oyama, Kei; Shiraishi, Masaru; Iijima, Toshio; Tsutsui, Ken-Ichiro

    2017-12-01

    Multi-unit recording has been one of the most widely used techniques to investigate the correlation between multiple neuronal activities and behavior. However, a common problem of currently used multi-channel electrodes is their physical weakness. In this study, we developed a novel multi-channel electrode with sufficient physical strength to penetrate a thickened dura mater. This electrode consists of low-cost materials and is easily fabricated, and it enables recording without removing dura mater, thereby reducing the risk of inflammation, infection, or brain herniation. The low-cost multi-channel electrode developed in this study would be a useful tool for chronic recording in behaving animals. Copyright © 2017. Published by Elsevier B.V.

  12. Estimating the short-circuit impedance

    DEFF Research Database (Denmark)

    Nielsen, Arne Hejde; Pedersen, Knud Ole Helgesen; Poulsen, Niels Kjølstad

    1997-01-01

    A method for establishing a complex value of the short-circuit impedance from naturally occurring variations in voltage and current is discussed. It is the symmetrical three phase impedance at the fundamental grid frequency there is looked for. The positive sequence components in voltage...... and current are derived each period, and the short-circuit impedance is estimated from variations in these components created by load changes in the grid. Due to the noisy and dynamic grid with high harmonic distortion it is necessary to threat the calculated values statistical. This is done recursively...... through a RLS-algorithm. The algorithms have been tested and implemented on a PC at a 132 kV substation supplying a rolling mill. Knowing the short-circuit impedance gives the rolling mill an opportunity to adjust the arc furnace operation to keep flicker below a certain level. Therefore, the PC performs...

  13. Direct stent puncture technique for intraluminal stent recanalization in the superficial femoral and popliteal arteries in-stent occlusion: Outcomes from a prospective clinical analysis of diabetics with critical limb ischemia

    Energy Technology Data Exchange (ETDEWEB)

    Palena, Luis Mariano, E-mail: marianopalena@hotmail.com; Manzi, Marco

    2013-07-15

    Purpose: To evaluate the efficacy and safety of “Direct Stent Puncture” technique for intraluminal stent recanalization in the femoro-popliteal segments. Methods and Materials: A cohort of diabetics who had symptomatic in-stent occlusion of the superficial femoral or popliteal arteries underwent endovascular recanalization. After antegrade failure, direct stent puncture technique was performed. The primary end-point was to efficacy assessment, intended as technical success and clinical improvement. The secondary end-point was safety assessment, intended as free of complication rate. Results: Fifty-four patients (37 men; 73.6 ± 8.5 years) underwent direct stent puncture technique, after several unsuccessful antegrade attempts to cross the occluded stent. Technical success for intraluminal stent recanalization was achieved in 53/54 (98.2%) of cases and failed in 1/54 (1.8%). Clinical improvement was obtained in 51/54 (94.4%) of cases, with regression of the clinical symptoms and improvement of the TcPO{sub 2}, from 3 ± 18 mmHg to 43 ± 11 mmHg after 15 days (p < 0.001). Free of complications rate was 92.5%. In 2/54 (3.7%) of cases distal embolization occurred, in 1/54 (1.9%) case a sudden vessel thrombosis was diagnosed after 12 hours and in 1/54 (1.9%) case hematoma at the stent puncture site was observed. Conclusions: Direct Stent Puncture technique is an efficacy and safety option for intraluminal stent recanalization in the femoro-popliteal segment in-stent occlusion.

  14. Multi-channel spintronic transistor design based on magnetoelectric barriers and spin-orbital effects

    International Nuclear Information System (INIS)

    Fujita, T; Jalil, M B A; Tan, S G

    2008-01-01

    We present a spin transistor design based on spin-orbital interactions in a two-dimensional electron gas, with magnetic barriers induced by a patterned ferromagnetic gate. The proposed device overcomes certain shortcomings of previous spin transistor designs such as long device length and degradation of conductance modulation for multi-channel transport. The robustness of our device for multi-channel transport is unique in spin transistor designs based on spin-orbit coupling. The device is more practical in fabrication and experimental respects compared to previously conceived single-mode spin transistors

  15. Journal bearing impedance descriptions for rotordynamic applications

    NARCIS (Netherlands)

    Childs, D.W.; Moes, H.; Leeuwen, van H.J.

    1977-01-01

    Bearing impedance vectors are introduced for plain journal bearings which define the bearing reaction force components as a function of the bearing motion. Impedance descriptions are developed directly for the approximate Ocvirk (short) and Sommerfeld (long) bearing solutions. The impedance vector

  16. Impedance of porous IT-SOFC LSCF:CGO composite cathodes

    DEFF Research Database (Denmark)

    Nielsen, Jimmi; Jacobsen, Torben; Wandel, Marie

    2011-01-01

    The impedance of technological relevant LSCF:CGO composite IT-SOFC cathodes was studied over a very wide performance range. This was experimentally achieved by impedance measurements on symmetrical cells with three different microstructures in the temperature range 550–850 °C. In order to account...... for the impedance spectra of the poor performing cathodes the Finite-Length-Gerischer (FLG) impedance was derived and applied to the impedance data. The FLG impedance describes for a given microstructure the situation where the cathode is made too thin from a cathode development point of view. The moderate...... performing cathodes showed a slightly suppressed Gerischer impedance, while the impedance spectra of the well performing cathodes showed the presence of an arc due to oxygen gas diffusion. The overall impedance of the well performing cathodes could be described with a slightly suppressed Gerischer impedance...

  17. Multi-channel temperature measurement system for automotive battery stack

    Science.gov (United States)

    Lewczuk, Radoslaw; Wojtkowski, Wojciech

    2017-08-01

    A multi-channel temperature measurement system for monitoring of automotive battery stack is presented in the paper. The presented system is a complete battery temperature measuring system for hybrid / electric vehicles that incorporates multi-channel temperature measurements with digital temperature sensors communicating through 1-Wire buses, individual 1-Wire bus for each sensor for parallel computing (parallel measurements instead of sequential), FPGA device which collects data from sensors and translates it for CAN bus frames. CAN bus is incorporated for communication with car Battery Management System and uses additional CAN bus controller which communicates with FPGA device through SPI bus. The described system can parallel measure up to 12 temperatures but can be easily extended in the future in case of additional needs. The structure of the system as well as particular devices are described in the paper. Selected results of experimental investigations which show proper operation of the system are presented as well.

  18. Very Fast Algorithms and Detection Performance of Multi-Channel and 2-D Parametric Adaptive Matched Filters for Airborne Radar

    National Research Council Canada - National Science Library

    Marple, Jr., S. L; Corbell, Phillip M; Rangaswamy, Muralidhar

    2007-01-01

    ...) detection statistics under exactly known covariance (the clairvoyant case). Improved versions of the two original multichannel PAMF algorithms, one new multichannel PAMF algorithm, and a new two-dimensional (2D) PAMF algorithm...

  19. Impedance analysis of acupuncture points and pathways

    International Nuclear Information System (INIS)

    Teplan, Michal; Kukucka, Marek; Ondrejkovicová, Alena

    2011-01-01

    Investigation of impedance characteristics of acupuncture points from acoustic to radio frequency range is addressed. Discernment and localization of acupuncture points in initial single subject study was unsuccessfully attempted by impedance map technique. Vector impedance analyses determined possible resonant zones in MHz region.

  20. ABORt: Acknowledgement-Based Opportunistic Routing Protocol for High Data Rate Multichannel WSNs

    Directory of Open Access Journals (Sweden)

    Hamadoun Tall

    2017-10-01

    Full Text Available The ease of deployment and the auto-configuration capabilities of Wireless Sensor Networks (WSNs make them very attractive in different domains like environmental, home automation or heath care applications. The use of multichannel communications in WSNs helps to improve the overall performance of the network. However, in heavy traffic scenarios, routing protocols should be adapted to allow load balancing and to avoid losing data packets due to congestion and queue overflow. In this paper, we present an Acknowledgement-Based Opportunistic Routing (ABORt protocol designed for high data rate multichannel WSNs. It is a low overhead protocol that does not rely on synchronization for control traffic exchange during the operational phase of the network. ABORt is an opportunistic protocol that relies on link layer acknowledgements to disseminate routing metrics, which helps to reduce overhead. The performance of ABORt is evaluated using the Cooja simulator and the obtained results show that ABORt has a high packet delivery ratio with reduced packet end-to-end delay compared to two single channel routing protocols and two multichannel routing protocols that use number of hops and expected transmission count as routing metrics.

  1. Modeling and Grid impedance Variation Analysis of Parallel Connected Grid Connected Inverter based on Impedance Based Harmonic Analysis

    DEFF Research Database (Denmark)

    Kwon, JunBum; Wang, Xiongfei; Bak, Claus Leth

    2014-01-01

    This paper addresses the harmonic compensation error problem existing with parallel connected inverter in the same grid interface conditions by means of impedance-based analysis and modeling. Unlike the single grid connected inverter, it is found that multiple parallel connected inverters and grid...... impedance can make influence to each other if they each have a harmonic compensation function. The analysis method proposed in this paper is based on the relationship between the overall output impedance and input impedance of parallel connected inverter, where controller gain design method, which can...

  2. Iron-Deficiency Anemia Leading to Transient Ischemic Attacks due to Intraluminal Carotid Artery Thrombus

    Directory of Open Access Journals (Sweden)

    H. Z. Batur Caglayan

    2013-01-01

    Full Text Available Reactive thrombocytosis secondary to iron-deficiency anemia (IDA is a rare but recognized cause of stroke. We report the case of a patient with iron-deficiency anemia presenting with multiple transient ischemic attacks (TIA due to intraluminal thrombus of an internal carotid artery. The putative mechanisms underlying anemia and stroke syndromes are not completely understood, and it is believed that iron deficiency may cause ischemic stroke by several potential mechanisms. Thrombocytosis is often associated with iron deficiency, and microcytosis produces a reduction in the red cell deformability and could produce a hypercoagulable state. The platelet count and function observed in iron-deficiency anemia could act synergistically to promote thrombus formation, especially in the setting of an underlying atherosclerotic disease. The presence of floating thrombus in a patient with clinical and MRI evidence of stroke represents a significant therapeutic dilemma and requires immediate decision about treatment.

  3. The LEP impedance model

    Energy Technology Data Exchange (ETDEWEB)

    Zotter, B [European Organization for Nuclear Research, Geneva (Switzerland)

    1996-08-01

    This report describes a number of measurements and computations of the impedance of the Large Electron Positron collider LEP at CERN. The work has been performed over several years, together with D. Brandt, K. Cornelis, A. Hofmann, G. Sabbi and many others. The agreement between measurements of single bunch instabilities on the machine and computer simulations is in general excellent and gives confidence in the impedance model used. (author)

  4. Multi-channel coherent perfect absorbers

    KAUST Repository

    Bai, Ping

    2016-05-18

    The absorption efficiency of a coherent perfect absorber usually depends on the phase coherence of the incident waves on the surfaces. Here, we present a scheme to create a multi-channel coherent perfect absorber in which the constraint of phase coherence is loosened. The scheme has a multi-layer structure such that incident waves in different channels with different angular momenta can be simultaneously and perfectly absorbed. This absorber is robust in achieving high absorption efficiency even if the incident waves become "incoherent" and possess "random" wave fronts. Our work demonstrates a unique approach to designing highly efficient metamaterial absorbers. © CopyrightEPLA, 2016.

  5. Multi-channel coherent perfect absorbers

    KAUST Repository

    Bai, Ping; Wu, Ying; Lai, Yun

    2016-01-01

    The absorption efficiency of a coherent perfect absorber usually depends on the phase coherence of the incident waves on the surfaces. Here, we present a scheme to create a multi-channel coherent perfect absorber in which the constraint of phase coherence is loosened. The scheme has a multi-layer structure such that incident waves in different channels with different angular momenta can be simultaneously and perfectly absorbed. This absorber is robust in achieving high absorption efficiency even if the incident waves become "incoherent" and possess "random" wave fronts. Our work demonstrates a unique approach to designing highly efficient metamaterial absorbers. © CopyrightEPLA, 2016.

  6. Impedance analysis of the PEP-II vacuum chamber

    International Nuclear Information System (INIS)

    Ng, C.K.; Weiland, T.

    1995-05-01

    The PEP-II high energy ring (HER) vacuum chamber consists of a copper tube with periodically spaced pumping slots. The impedance of the vacuum chamber due to the slots is analyzed. Both narrow-band and broadband impedances are considered as well as longitudinal and transverse components thereof. It is found that although the broad-band impedance is tolerable, the narrow-band impedance may exceed the instability limit given by the natural damping with no feedback system on. Traveling wave modes in the chamber are the major source of this high value narrow-band impedance. We also study the dependences of the impedance on the slot length and the geometrical cross section

  7. Numerical investigation of multichannel laser beam phase locking in turbulent atmosphere

    Energy Technology Data Exchange (ETDEWEB)

    Volkov, V A; Volkov, M V; Garanin, S G; Starikov, F A [Russian Federal Nuclear Center ' All-Russian Research Institute of Experimental Physics' , Sarov, Nizhnii Novgorod region (Russian Federation)

    2015-12-31

    The efficiency of coherent multichannel beam combining under focusing through a turbulent medium on a target in the cases of phase conjugation and target irradiation in the feedback loop is investigated numerically in various approximations. The conditions of efficient focusing of multichannel radiation on the target are found. It is shown that the coherent beam combining with target irradiation in the feedback loop, which does not require a reference beam and wavefront measurements, is as good as the phase conjugation approach in the efficiency of focusing. It is found that the main effect of focusing is provided by properly chosen phase shifts in the channels, whereas taking into account local wavefront tip tilts weakly affects the result. (control of laser radiation parameters)

  8. A compact broadband nonsynchronous noncommensurate impedance transformer

    DEFF Research Database (Denmark)

    Zhurbenko, Vitaliy; Kim, Kseniya; Narenda, Kumar

    2012-01-01

    Nonsynchronous noncommensurate impedance transformers consist of a combination of high‐ and low‐impedance transmission lines. High‐impedance lines have narrow tracks in strip and microstrip technology, which allows for high flexibility and miniaturization of the layout in comparison...... to the traditional tapered line transformers. This flexibility of the broadband nonsynchronous noncommensurate impedance transformers is experimentally demonstrated in this article allowing the length reduction by almost three times. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:1832–1835, 2012; View...

  9. Impedance of SOFC electrodes: A review and a comprehensive case study on the impedance of LSM:YSZ cathodes

    DEFF Research Database (Denmark)

    Nielsen, Jimmi; Hjelm, Johan

    2014-01-01

    It was shown through a comprehensive impedance spectroscopy study that the impedance of the classic composite LSM:YSZ (lanthanum strontium manganite and yttria stabilized zirconia) solid oxide fuel cell (SOFC) cathode can be described well with porous electrode theory. Furthermore, it was illustr......It was shown through a comprehensive impedance spectroscopy study that the impedance of the classic composite LSM:YSZ (lanthanum strontium manganite and yttria stabilized zirconia) solid oxide fuel cell (SOFC) cathode can be described well with porous electrode theory. Furthermore......, it was illustrated through a literature review on SOFC electrodes that porous electrode theory not only describes the classic LSM:YSZ SOFC cathode well, but SOFC electrodes in general. The extensive impedance spectroscopy study of LSM:YSZ cathodes consisted of measurements on cathodes with three different sintering...... temperatures and hence different microstructures and varying degrees of LSM/YSZ solid state interactions. LSM based composite cathodes, where YSZ was replaced with CGO was also studied in order to acquire further knowledge on the chemical compatibility between LSM and YSZ. All impedance measurements were...

  10. The Role of Multichannel Marketing in Customer Retention and Loyalty: Study in Emerald Bank Customer in Indonesia

    Directory of Open Access Journals (Sweden)

    Ambarwati Ambarwati

    2015-09-01

    Full Text Available Attention on the relationship between customer retention, customer loyalty, and customer satisfaction that serves as "seed" of customer loyalty highlight the important factors for multichannel management. With the growing trends of people in investing their money in bank for securities need to be responded by the marketing department to create better marketing strategies. The purpose of this study is to examine and explain the effect of a multichannel bank on emerald customers retention   in one of the largest SOE bank in Indonesia, in the city of Surabaya, BNI (Bank Negara Indonesia toward customer  satisfaction, loyalty and customer  retention. This study develops the theory  of  mix marketing by using multichannel  as one of the elements that can increase customer retention   using satisfaction mediation and customer loyalty. Mechanical determination of sample units in this study is a  purposive sampling, of 89 respondents. Generalized Structured Component Analysis (GSCA was applied to test the hypotheses. The results of this study indicate that direct multichannel not  significantly effect the customer retention. Customer satisfaction can not be a perfect mediation  and the customer loyalty can be a perfect mediation in the relationship between multichannel and customer retention. This study contributes to the banking industry in applying the concept of the mix marketing.

  11. Impedance models in time domain

    NARCIS (Netherlands)

    Rienstra, S.W.

    2005-01-01

    Necessary conditions for an impedance function are derived. Methods available in the literature are discussed. A format with recipe is proposed for an exact impedance condition in time domain on a time grid, based on the Helmholtz resonator model. An explicit solution is given of a pulse reflecting

  12. Multi-Channel Maximum Likelihood Pitch Estimation

    DEFF Research Database (Denmark)

    Christensen, Mads Græsbøll

    2012-01-01

    In this paper, a method for multi-channel pitch estimation is proposed. The method is a maximum likelihood estimator and is based on a parametric model where the signals in the various channels share the same fundamental frequency but can have different amplitudes, phases, and noise characteristics....... This essentially means that the model allows for different conditions in the various channels, like different signal-to-noise ratios, microphone characteristics and reverberation. Moreover, the method does not assume that a certain array structure is used but rather relies on a more general model and is hence...

  13. Simple multifunction discriminator for multichannel triggers

    International Nuclear Information System (INIS)

    Maier, M.R.

    1982-10-01

    A simple version of a multifunction timing discriminator using only two integrated circuits is presented. It can be configured as a leading edge, a constant fraction, a zero cross or a dual threshold timing discriminator. Since so few parts are used, it is well suited for building multichannel timing discriminators. Two versions of this circuit are described: a quadruple multifunction discriminator and an octal constant fraction trigger. The different compromises made in these units are discussed. Results for walk and jitter obtained with these are presented and possible improvements are disussed

  14. Feasibility study of applying a multi-channel analysis model to on-line core monitoring system

    International Nuclear Information System (INIS)

    In, W. K.; Yoo, Y. J.; Hwang, D. H.; Jun, T. H.

    1998-01-01

    A feasibility study was performed to evaluate the effect of implementing a multi-channel analysis model in on-line core monitoring system. A simplified thermal-hydraulic model has been used in the on-line core monitoring system of digital PWR. The design procedure, core thermal margin and computation time were investigated in case of replacing the simplified model with the multi-channel analysis model. For the given ranges of limiting conditions for operation in Yonggwang Unit 3 Cycle 1, the minimum DNBR of the simplified thermal-hydraulic code CETOP-D was compared to that of the multi-channel analysis code MATRA. A CETOP-D tuning is additionally required to ensure the accurate and conservative DNBR calculation but the MATRA tuning is not necessary. MATRA appeared to increase the DNBR overpower margin from 2.5% to 6% over the CETOP-D margin. MATRA took approximately 1 second to compute DNBR on the HP9000 workstation system, which is longer than the DNBR computation time of CETOP-D. It is, however, fast enough to perform the on-line monitoring of DNBR. It can be therefore concluded that the application of the multi-channel analysis model MATRA in the on-line core monitoring system is feasible

  15. Field microcomputerized multichannel γ ray spectrometer based on notebook computer

    International Nuclear Information System (INIS)

    Jia Wenyi; Wei Biao; Zhou Rongsheng; Li Guodong; Tang Hong

    1996-01-01

    Currently, field γ ray spectrometry can not rapidly measure γ ray full spectrum, so a field microcomputerized multichannel γ ray spectrometer based on notebook computer is described, and the γ ray full spectrum can be rapidly measured in the field

  16. Online purchase intentions: A multi-channel store image perspective

    NARCIS (Netherlands)

    Verhagen, T.; van Dolen, W.

    2009-01-01

    The advantages of the bricks-and-clicks retail format in the battle for the online customer has been widely discussed but empirical research on it has been limited. We applied a multi-channel store image perspective to assess its influence on online purchase intentions. Drawing on a sample of 630

  17. Salt Intrusion, Tides and Mixing in Multi-channel Estuaries

    NARCIS (Netherlands)

    Nguyen, A.D.

    2008-01-01

    Multi-channel estuaries, such as the Mekong Delta in Vietnam and the Scheldt in the Netherlands, have characteristics of both the river and the sea, forming a unique environment influenced by tidal movements of the sea and freshwater flow of the river. This study addresses a number of knowledge gaps

  18. Software Configurable Multichannel Transceiver

    Science.gov (United States)

    Freudinger, Lawrence C.; Cornelius, Harold; Hickling, Ron; Brooks, Walter

    2009-01-01

    Emerging test instrumentation and test scenarios increasingly require network communication to manage complexity. Adapting wireless communication infrastructure to accommodate challenging testing needs can benefit from reconfigurable radio technology. A fundamental requirement for a software-definable radio system is independence from carrier frequencies, one of the radio components that to date has seen only limited progress toward programmability. This paper overviews an ongoing project to validate the viability of a promising chipset that performs conversion of radio frequency (RF) signals directly into digital data for the wireless receiver and, for the transmitter, converts digital data into RF signals. The Software Configurable Multichannel Transceiver (SCMT) enables four transmitters and four receivers in a single unit the size of a commodity disk drive, programmable for any frequency band between 1 MHz and 6 GHz.

  19. VISUALIZATION OF BIOLOGICAL TISSUE IMPEDANCE PARAMETERS

    Directory of Open Access Journals (Sweden)

    V. I. Bankov

    2016-01-01

    Full Text Available Objective. Investigation the opportunity for measurement of biological tissue impedance to visualize its parameters.Materials and methods. Studies were undertook on the experimental facility, consists of registrating measuring cell, constructed from flat inductors system, formed in oscillatory circuit, herewith investigated biological tissue is the part of this oscillatory circuit. An excitation of oscillatory circuit fulfilled by means of exciter inductor which forms impulse complex modulated electromagnetic field (ICM EMF. The measurement process and visualizations provided by set of certificated instruments: a digital oscillograph AKTAKOM ADS-2221MV, a digital generator АКТАКОМ AWG-4150 (both with software and a gauge RLC E7-22. Comparative dynamic studies of fixed volume and weight pig’s blood, adipose tissue, muscular tissue impedance were conducted by contact versus contactless methods. Contactless method in contrast to contact method gives opportunity to obtain the real morphological visualization of biological tissue irrespective of their nature.Results. Comparison of contact and contactless methods of impedance measurement shows that the inductance to capacitance ratio X(L / X(C was equal: 17 – for muscular tissue, 4 – for blood, 1 – for adipose tissue. It demonstrates the technical correspondence of both impedance registration methods. If propose the base relevance of X (L and X (C parameters for biological tissue impedance so contactless measurement method for sure shows insulating properties of adipose tissue and high conductivity for blood and muscular tissue in fixed volume-weight parameters. Registration of biological tissue impedance complex parameters by contactless method with the help of induced ICM EMF in fixed volume of biological tissue uncovers the most important informative volumes to characterize morphofunctional condition of biological tissue namely X (L / X (C.Conclusion. Contactless method of biological

  20. Mechanical Impedance Modeling of Human Arm: A survey

    Science.gov (United States)

    Puzi, A. Ahmad; Sidek, S. N.; Sado, F.

    2017-03-01

    Human arm mechanical impedance plays a vital role in describing motion ability of the upper limb. One of the impedance parameters is stiffness which is defined as the ratio of an applied force to the measured deformation of the muscle. The arm mechanical impedance modeling is useful in order to develop a better controller for system that interacts with human as such an automated robot-assisted platform for automated rehabilitation training. The aim of the survey is to summarize the existing mechanical impedance models of human upper limb so to justify the need to have an improved version of the arm model in order to facilitate the development of better controller of such systems with ever increase in complexity. In particular, the paper will address the following issue: Human motor control and motor learning, constant and variable impedance models, methods for measuring mechanical impedance and mechanical impedance modeling techniques.

  1. Experimental researches and comparison on aerodynamic parameters and cleaning efficiency of multi-level multi-channel cyclone

    Directory of Open Access Journals (Sweden)

    Aleksandras Chlebnikovas

    2015-10-01

    Full Text Available Multi-level multi-channel cyclone – the lately designed air cleaning device that can remove ultra-fine 20 μm particulatematter (PM from dusted air and reach over 95% of the overall cleaning efficiency. Multi-channel cyclone technology is based on centrifugal forces and has the resulting additional filtering process operation. Multi-level structure of cyclone allows to achieve higher air flow cleaning capacity at the same dimensions of the device, thus saving installation space required for the job, production and operating costs. Studies have examined the air flow parameters change in one–, two– and three–levels multichannel cyclone. These constructions differ according to the productivity of cleaned air under the constant peripheral and transitional (50/50 case air flow relations. Accordance with the results of air flow dynamics – velocity distribution of multi-channel cyclone, aerodynamic resistance and efficiency can be judged on the flow turbulence, the flow channel cross-section and select the most appropriate application. Cleaning efficiency studies were carried out using fine granite and wood ashes PM. The maximum cleaning efficiency was 93.3%, at an average of 4.5 g/m3, the aerodynamic resistance was equal to 1525 Pa.

  2. A Novel Spectrally Efficient Asynchronous Multi-Channel MAC Using a Half-Duplex Transceiver for Wireless Networks

    Directory of Open Access Journals (Sweden)

    Abdullah Devendiran

    2018-01-01

    Full Text Available Multi-channel medium access control (MAC protocols maximize network performance by enabling concurrent wireless transmissions over non-interfering channels. Despite physical layer advancements, the underlying IEEE 802.11 MAC standard cannot fully exploit features and support high-performance applications. In this work, we propose the novel spectrally efficient asynchronous multi-channel MAC (SA-MMAC protocol for wireless networks using a single half-duplex transceiver. A full-duplex mode of operation on data channels reduces the signaling overhead and boosts the spectrum efficiency. A revamped contention mechanism of IEEE 802.11 addresses the multi-channel hidden terminal problem, and a jamming signal from the receiver addresses the collisions in control signals. Furthermore, the control channel is used for data transmissions to increase the bandwidth utilization but under a restricted half-duplex mode to avoid causing a bottleneck situation. The simulator is tested for correctness. The results suggest that the protocol can work well on 3, 4, or 12 concurrent channels with high node density, providing about 12.5 times more throughput than IEEE 802.11 and 18% to 95% more throughput than its multi-channel variants under saturated traffic conditions.

  3. Impedance of the PEP-II DIP screen

    Energy Technology Data Exchange (ETDEWEB)

    Ng, C -K [Stanford Linear Accelerator Center, Menlo Park, CA (United States); Weiland, T

    1996-08-01

    The vacuum chamber of a storage ring normally consists of periodically spaced pumping slots. The longitudinal impedance of slots are analyzed in this paper. It is found that although the broad-band impedance is tolerable, the narrow-band impedance, as a consequence of the periodicity of the slots, may exceed the stability limit given by natural damping with no feedback system on. Based on this analysis, the PEP-II distributed-ion-pump (DIP) screen uses long grooves with hidden holes cut halfway to reduce both the broad-band and narrow-band impedances. (author)

  4. Impedance of the PEP-II DIP screen

    International Nuclear Information System (INIS)

    Ng, C.K.; Weiland, T.

    1995-09-01

    The vacuum chamber of a storage ring normally consists of periodically spaced pumping slots. The longitudinal impedance of slots are analyzed in this paper. It is found that although the broad-band impedance is tolerable, the narrow-band impedance, as a consequence of the periodicity of the slots, may exceed the stability limit given by natural damping with no feedback system on. Based on this analysis, the PEP-II distributed-ion-pump (DIP) screen uses long grooves with hidden holes cut halfway to reduce both the broad-band and narrow-band impedances

  5. Intraluminal occlusion of the seminal duct by laser and Histoacryl: Two non-invasive alternatives for vasectomy

    Science.gov (United States)

    Freitag, B.; Sroka, R.; Koelle, S.; Becker, A. J.; Khoder, W.; Pongratz, T.; Stief, C. G.; Trottmann, M.

    2014-03-01

    Introduction and objective: Vasectomy is a well-established method in family control. Even though it is a safe and low risk operation, this surgery is invasive and difficult to reverse. Therefore the aim of this study was to investigate new non-invasive methods for occlusion of the seminal duct. Material and Methods: Seminal duct tissue was obtained from patients (n=30) suffering from prostate cancer and therefore undergoing prostatectomy. In a first set of experiments, the seminal duct was occluded by intraluminal application of Histoacryl® (Braun Aesculap AG, Tuttlingen, Germany). In a 2nd set of experiments, endoluminal laser induced occlusion was performed. Four different laser wavelengths (1940nm, 1470nm, 1064nm, 940nm) and different sets of laser parameters (e.g. power, exposure duration, fibre diameter, energy applied) were compared. Effectiveness of occlusion of the seminal duct was proven by post-treatment irrigation flow measurement, as well as by morphological analyses. To evaluate a potential damage of the surrounding tissue, external temperature was measured using a thermometer during laser application. Results: Intraluminal application of Histoacryl® induced an immediate and complete occlusion of the seminal duct. The underlying connective tissue maintained its functional integrity after this treatment. By laser light application to a Histoacryl® block, a hole could be created into the block thus indicating the possibility of recanalization. Treatment with laser energy resulted in shrinkage of the ductal lumen. The laser application generally caused necrosis in the epithelium and induced formation of vacuoles in the underlying connective tissue. As described for endoluminal varicose treatment, this distinct local reaction might result in an intense inflammation leading to a functional occlusion of the vas deferens. Conclusions: Both laser-induced occlusion and application of Histoacryl® are fast and simple techniques which may be able to achieve a

  6. Elimination of the Respiratory Effect on the Thoracic Impedance Signal with Whole-body Impedance Cardiography

    Czech Academy of Sciences Publication Activity Database

    Jurák, Pavel; Halámek, Josef; Vondra, Vlastimil; Viščor, Ivo; Lipoldová, J.; Plachý, M.

    2010-01-01

    Roč. 37, - (2010), s. 1051-1054 ISSN 0276-6574 R&D Projects: GA AV ČR IAA200650801 Institutional research plan: CEZ:AV0Z20650511 Keywords : respiratory effect * thoracic impedance signal * impedance cardiography Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering http://cinc.mit.edu/archives/2010/pdf/1051.pdf

  7. New-fashioned Multi-channel Analyzer Based on Bipartition Method

    International Nuclear Information System (INIS)

    Liu Mingjian; Zhang Yan; Yan Xuekun; Chen Ying

    2009-01-01

    A new-fashioned digital-analog converter (DAC) which can find the pulse-signal amplitude through dichotomy is devised. With this new DAC method, a 256-channel multi-channel pulse amplitude analyzer (MCA) is designed successfully, and its hardware and software are introduced in detail. This provides a new method for designing MCA. (authors)

  8. Identification of irradiated potatoes by impedance

    International Nuclear Information System (INIS)

    Singh, Rita; Singh, Antaryami; Wadhawan, A.K.

    1997-01-01

    The electrical impedance of potatoes irradiated at 60, 90, 150 and 1000 Gy was measured using various frequencies of alternating current. The impedance of the irradiated potatoes was higher than the unirradiated potatoes particularly in the frequency range of 100 Hz to 10 kHz. The ratio of the impedance at 5 kHz to that at 50 Hz (Z5k/Z50) was found to be the best indicator for detection of radiation treatment. (author). 4 refs., 2 figs

  9. SPATIAL VARIABILITY OF PEDOZEMS MECHANICAL IMPEDANCE

    Directory of Open Access Journals (Sweden)

    Zhukov A.V.

    2013-04-01

    Full Text Available We studied the spatial variability of pedozem mechanical impedance in ResearchRemediation Center of the Dnipropetrovsk State Agrarian University in Ordzhonikidze. Thestatistical distribution of the soil mechanical impedance within the studied area is characterized by deviation from the normal law in 0–10 and 30–50 cm layers from the surface. 2D and 3D modeling shows the structural design of the soil as locations of high mechanical impedance which found in the soils with less hardness.

  10. Small Signal Loudspeaker Impedance Emulator

    DEFF Research Database (Denmark)

    Iversen, Niels Elkjær; Knott, Arnold

    2014-01-01

    Specifying the performance of audio amplifiers is typically done by playing sine waves into a pure ohmic load. However real loudspeaker impedances are not purely ohmic but characterized by the mechanical resonance between the mass of the diaphragm and the compliance of its suspension which vary...... from driver to driver. Therefore, a loudspeaker emulator capable of adjusting its impedance to that of a given driver is desired for measurement purposes. This paper proposes a loudspeaker emulator circuit for small signals. Simulations and experimental results are compared and show that it is possible...... to emulate the loudspeaker impedance with an electric circuit and that its resonance frequency can be changed by tuning two resistors....

  11. Small-signal Loudspeaker Impedance Emulator

    DEFF Research Database (Denmark)

    Knott, Arnold; Iversen, Niels Elkjær

    2014-01-01

    Specifying the performance of audio ampliers is typically done by playing sine waves into a pure ohmic load. However real loudspeaker impedances are not purely ohmic but characterised by the mechanical resonance between the mass of the diaphragm and the compliance of its' suspension which vary from...... driver to driver. Therefore a loudspeaker emulator capable of adjusting its' impedance to a given driver is in need for measurement purposes. This paper proposes a loudspeaker emulator circuit for small signals. Simulations and experimental results are compared and show that it is possible to emulate...... the loudspeaker impedance with an electric circuit and that its' resonance frequency can be changed by tuning two resistors....

  12. Increased proximal acid reflux is associated with early readmission following lung transplantation.

    Science.gov (United States)

    Lo, W-K; Goldberg, H J; Burakoff, R; Feldman, N; Chan, W W

    2016-02-01

    Gastroesophageal reflux disease has been associated with poor outcomes following lung transplantation. However, the association between pretransplant reflux and post-transplant readmission, an indicator of early clinical outcome, has not been previously assessed. This was a retrospective cohort study of lung transplant recipients undergoing pretransplant multichannel intraluminal impedance and pH (MII-pH) study off acid suppression at a tertiary care center since 2007. Subjects with pretransplant fundoplication were excluded. Time to readmission was defined as duration from post-transplant discharge to next hospital admission for any reason. Subgroup analysis was performed to exclude elective readmissions. Time-to-event analysis was performed using Cox proportional hazards model, with appropriate censoring. Forty-three subjects (60% men, mean age: 57, median follow-up: 1.7 years) met inclusion criteria for the study. Patient demographics and pretransplant cardiopulmonary function were similar between readmission cohorts. Time to all-cause readmission was associated with increased distal acid episodes (HR: 3.15, p = 0.04) and proximal acid episodes (HR: 3.61, p = 0.008) on impedance, increased acid exposure on pH (HR: 2.22, p = 0.04), and elevated Demeester score (HR: 2.26, p = 0.03). When elective readmissions were excluded, early readmission remained significantly associated with increased proximal acid reflux episodes (HR: 2.49, p = 0.04). All findings were confirmed on Kaplan-Meier analysis. Elevated proximal acid reflux on pretransplant MII-pH testing was associated with early readmission following lung transplantation, even after excluding elective readmissions. Exposure to severe acid reflux has measurable effects on early postoperative outcomes such as readmission, and aggressive early antireflux therapy should be considered. © 2015 John Wiley & Sons Ltd.

  13. The prevalence of gastro-esophageal reflux disease and esophageal dysmotility in Chinese patients with idiopathic pulmonary fibrosis.

    Science.gov (United States)

    Gao, Feng; Hobson, Anthony Robert; Shang, Zhan Min; Pei, Yan Xiang; Gao, Yan; Wang, Jian Xin; Huang, Wan Nong

    2015-02-19

    The cause of idiopathic pulmonary fibrosis (IPF) remains unknown, yet gastro-esophageal reflux disease (GERD) is highly prevalent in this population. GERD prevalence was studied, and esophageal function tests (EFT) were assessed in Chinese IPF patients. We prospectively studied 69 IPF patients who undertook both stationary High Resolution esophageal Manometry/Impedance (HRiM) and 24-hour esophageal Multi-Channel Intraluminal Impedance with pH Recordings (MII/pH). Patients were divided into GERD+ and GERD- groups according to pH results. Controls were HRiM treated healthy volunteers, and patients without IPF received HRiM and MII/pH diagnosed with GERD. 69 IPF patients, 62 healthy volunteers, and 88 IPF negative GERD patients were selected. GERD prevalence in IPF was 43/69 (62.3%), and 58.1% of patients presented with at least one typical symptom. Symptoms had a sensitivity of 58.1%, a specificity of 61.6%, a positive predictive value of 71.4% and a negative predictive of 47.1%. Compared with healthy volunteers, IPF patients had significantly decreased lower esophageal sphincter pressure (LESP), upper esophageal sphincter pressure (UESP) and complete bolus transit rate (CBTR). By contrast, IPF patients had increased total bolus transit time and prevalence of weak peristalsis. MII/pH showed that one third of IPF patients had abnormal distal and proximal reflux, especially non-acid reflux. Compared with GERD patients without IPF, GERD patients with IPF had significantly decreased CBTR and UESP with increased bolus exposure time. GERD prevalence in IPF was high, but symptoms alone were an unreliable predictor of reflux. IPF patients had lower LESP and UESP, impaired esophageal peristalsis and bolus clearance function with more proximal reflux events.

  14. Integrated multi-channel vehicle-vehicle and vehicle-roadside communications for ITS

    Science.gov (United States)

    2008-12-01

    This research describes a medium access control (MAC) protocol to Enable multi-channel operation for dedicated short-range communication (DSRC). In particular, we focus on the challenge of supporting potentially high-bandwidth commercial or infotainm...

  15. How the Inductive Voltage Adder (IVA) output impedance affects impedance dynamics of a Self-Magnetic Pinch (SMP) diode

    Science.gov (United States)

    Renk, Timothy; Simpson, Sean; Webb, Timothy; Mazarakis, Michael; Kiefer, Mark

    2016-10-01

    The SMP diode, fielded on the RITS-6 (3.5-8.5 MV) IVA accelerator at Sandia National Laboratories, produces a focused electron beam (transmission line (MITL) center conductors, of 40 and 80 ohms flow impedance. We have operated in-situ heating and discharge-cleaning hardware in the load region, in order to address the tendency of some shots to undergo premature impedance (Z) collapse, defined as a fall in impedance beyond that due to normal movement of electrode plasmas that reduces the effective A-K gap. The goal of heating/cleaning was to reduce the volume of evolving gases near the A-K gap. Despite clear evidence that the cleaning techniques removed the proton portion of beam current, we observed no consistent increase in diode impedance (ZDIODE). This forced an examination of the role that the IVA flow impedance has on ZDIODE. A preliminary conclusion is that ZDIODE should be at least 1.5 times the flow impedance before ZDIODE is a parameter independent of flow impedance. This has implications for SMP as a load for a IVA, since ZDIODE >100 ohms has not been consistently demonstrated. Data analysis is ongoing, and latest results will be reported. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

  16. Impedance Modeling of Solid Oxide Fuel Cell Cathodes

    DEFF Research Database (Denmark)

    Mortensen, Jakob Egeberg; Søgaard, Martin; Jacobsen, Torben

    2010-01-01

    A 1-dimensional impedance model for a solid oxide fuel cell cathode is formulated and applied to a cathode consisting of 50/50 wt% strontium doped lanthanum cobaltite and gadolinia doped ceria. A total of 42 impedance spectra were recorded in the temperature range: 555-852°C and in the oxygen...... partial pressure range 0.028-1.00 atm. The recorded impedance spectra were successfully analyzed using the developed impedance model in the investigated temperature and oxygen partial pressure range. It is also demonstrated that the model can be used to predict how impedance spectra evolve with different...

  17. Skyrmion-based multi-channel racetrack

    Science.gov (United States)

    Song, Chengkun; Jin, Chendong; Wang, Jinshuai; Xia, Haiyan; Wang, Jianbo; Liu, Qingfang

    2017-11-01

    Magnetic skyrmions are promising for the application of racetrack memories, logic gates, and other nano-devices, owing to their topologically protected stability, small size, and low driving current. In this work, we propose a skyrmion-based multi-channel racetrack memory where the skyrmion moves in the selected channel by applying voltage-controlled magnetic anisotropy gates. It is demonstrated numerically that a current-dependent skyrmion Hall effect can be restrained by the additional potential of the voltage-controlled region, and the skyrmion velocity and moving channel in the racetrack can be operated by tuning the voltage-controlled magnetic anisotropy, gate position, and current density. Our results offer a potential application of racetrack memory based on skyrmions.

  18. Development of multi-channel gated integrator and PXI-DAQ system for nuclear detector arrays

    International Nuclear Information System (INIS)

    Kong Jie; Su Hong; Chen Zhiqiang; Dong Chengfu; Qian Yi; Gao Shanshan; Zhou Chaoyang; Lu Wan; Ye Ruiping; Ma Junbing

    2010-01-01

    A multi-channel gated integrator and PXI based data acquisition system have been developed for nuclear detector arrays with hundreds of detector units. The multi-channel gated integrator can be controlled by a programmable GI controller. The PXI-DAQ system consists of NI PXI-1033 chassis with several PXI-DAQ cards. The system software has a user-friendly GUI which is written in C language using LabWindows/CVI under Windows XP operating system. The performance of the PXI-DAQ system is very reliable and capable of handling event rate up to 40 kHz.

  19. Transverse impedance measurement in RHIC and the AGS

    Energy Technology Data Exchange (ETDEWEB)

    Biancacci, Nicolo [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Blaskiewicz, M. [Brookhaven National Lab. (BNL), Upton, NY (United States). Collider-Accelerator Dept.; Dutheil, Y. [Brookhaven National Lab. (BNL), Upton, NY (United States). Collider-Accelerator Dept.; Liu, C. [Brookhaven National Lab. (BNL), Upton, NY (United States). Collider-Accelerator Dept.; Mernick, M. [Brookhaven National Lab. (BNL), Upton, NY (United States). Collider-Accelerator Dept.; Minty, M. [Brookhaven National Lab. (BNL), Upton, NY (United States). Collider-Accelerator Dept.; White, S. M. [Brookhaven National Lab. (BNL), Upton, NY (United States). Collider-Accelerator Dept.

    2014-05-12

    The RHIC luminosity upgrade program aims for an increase of the polarized proton luminosity by a factor 2. To achieve this goal a significant increase in the beam intensity is foreseen. The beam coupling impedance could therefore represent a source of detrimental effects for beam quality and stability at high bunch intensities. For this reason it is essential to quantify the accelerator impedance budget and the major impedance sources, and possibly cure them. In this MD note we summarize the results of the 2013 transverse impedance measurements in the AGS and RHIC. The studies have been performed measuring the tune shift as a function of bunch intensity and deriving the total accelerator machine transverse impedance. For RHIC, we could obtain first promising results of impedance localization measurements as well.

  20. Very low cost multichannel analyzer with some additional features

    Energy Technology Data Exchange (ETDEWEB)

    Tudyka, Konrad, E-mail: konrad.tudyka@polsl.pl [Centre of Excellence-Gliwice Absolute Dating Methods Centre, Institute of Physics, Silesian University of Technology (Poland); Bluszcz, Andrzej [Centre of Excellence-Gliwice Absolute Dating Methods Centre, Institute of Physics, Silesian University of Technology (Poland)

    2011-12-11

    In this paper we present a multichannel analyzer (MCA) based on a digital signal controller (DSC). The multichannel analyzer is characterized by a very low cost and an additional feature of recording time intervals between pulses. The total cost of electronic parts used in construction of the MCA is around 50 USD. The electronic circuit is based on dsPIC30F2020 DSC unit from Microchip. The device has a 10-bit analogue-to-digital converter (ADC) which can sample and convert 2 samples per {mu}s. The DSC samples the input voltage continuously and detects incoming pulses. The data belonging to a detected pulse and its time stamp are sent to a PC on-line. The analysis of data stored on the PC is performed off-line with the help of a genetic algorithm (GA) used to fit the pulse shape function. This allows determination of amplitude of each individual pulse. The effective resolution varies with the pulse length and is typically 1000 channels for pulses approximately 4{mu}s long.

  1. Beam pipe impedances in the TRIUMF KAON factory

    International Nuclear Information System (INIS)

    Baartman, R.; Oram, C.J.

    1989-09-01

    The standard formalism for estimating longitudinal beam pipe impedances is given. Estimates of realistically obtainable impedances are developed. We show that where the impedance is critical an impedance divided by mode number of 1-2 Ω should be the design goal for the beam pipe group. However for machine design criteria and planning purposes 5 Ω should continue to be adopted so that sufficient contingency is present in the design

  2. A Multichannel Calorimetric Simultaneous Assay Platform Using a Microampere Constant-Current Looped Enthalpy Sensor Array

    Directory of Open Access Journals (Sweden)

    Hsien-Chin Wei

    2017-02-01

    Full Text Available Calorimetric biochemical measurements offer various advantages such as low waste, low cost, low sample consumption, short operating time, and labor-savings. Multichannel calorimeters can enhance the possibility of performing higher-throughput biochemical measurements. An enthalpy sensor (ES array is a key device in multichannel calorimeters. Most ES arrays use Wheatstone bridge amplifiers to condition the sensor signals, but such an approach is only suitable for null detection and low resistance sensors. To overcome these limitations, we have developed a multichannel calorimetric simultaneous assay (MCSA platform. An adjustable microampere constant-current (AMCC source was designed for exciting the ES array using a microampere current loop measurement circuit topology. The MCSA platform comprises a measurement unit, which contains a multichannel calorimeter and an automatic simultaneous injector, and a signal processing unit, which contains multiple ES signal conditioners and a data processor. This study focused on the construction of the MCSA platform; in particular, construction of the measurement circuit and calorimeter array in a single block. The performance of the platform, including current stability, temperature sensitivity and heat sensitivity, was evaluated. The sensor response time and calorimeter constants were given. The capability of the platform to detect relative enzyme activity was also demonstrated. The experimental results show that the proposed MCSA is a flexible and powerful biochemical measurement device with higher throughput than existing alternatives.

  3. Coordinating Multi-Channel Pricing of Seasonal Goods

    OpenAIRE

    Preetam Basu

    2012-01-01

    Advancement in information technology has opened new avenues for traditional retailers to expand their operations. Pricing, which has been a critical issue, is more important than ever before as traditional retailers pursue multi-channel sales. In this paper the author studies the pricing problem of a retailer selling a seasonal product simultaneously in a ‘brick and mortar’ store as well as online. Optimal prices are derived and different product-market conditions are determined under wh...

  4. Content-Based Multi-Channel Network Coding Algorithm in the Millimeter-Wave Sensor Network

    Directory of Open Access Journals (Sweden)

    Kai Lin

    2016-07-01

    Full Text Available With the development of wireless technology, the widespread use of 5G is already an irreversible trend, and millimeter-wave sensor networks are becoming more and more common. However, due to the high degree of complexity and bandwidth bottlenecks, the millimeter-wave sensor network still faces numerous problems. In this paper, we propose a novel content-based multi-channel network coding algorithm, which uses the functions of data fusion, multi-channel and network coding to improve the data transmission; the algorithm is referred to as content-based multi-channel network coding (CMNC. The CMNC algorithm provides a fusion-driven model based on the Dempster-Shafer (D-S evidence theory to classify the sensor nodes into different classes according to the data content. By using the result of the classification, the CMNC algorithm also provides the channel assignment strategy and uses network coding to further improve the quality of data transmission in the millimeter-wave sensor network. Extensive simulations are carried out and compared to other methods. Our simulation results show that the proposed CMNC algorithm can effectively improve the quality of data transmission and has better performance than the compared methods.

  5. Modeling degradation in SOEC impedance spectra

    DEFF Research Database (Denmark)

    Jensen, Søren Højgaard; Hauch, Anne; Knibbe, Ruth

    2013-01-01

    Solid oxide cell (SOC) performance is limited by various processes. One way to investigate these processes is by electrochemical impedance spectroscopy. In order to quantify and characterize the processes, an equivalent circuit can be used to model the SOC impedance spectra (IS). Unfortunately......, the optimal equivalent circuit is often unknown and to complicate matters further, several processes contribute to the SOC impedance - making detailed process characterization difficult. In this work we analyze and model a series of IS measured during steam electrolysis operation of an SOC. During testing......, degradation is only observed in the Ni/YSZ electrode and not in the electrolyte or the LSM/YSZ electrode. A batch fit of the differences between the IS shows that a modified Gerischer element provides a better fit to the Ni/YSZ electrode impedance than the frequently used RQ element - albeit neither...

  6. A low power Multi-Channel Analyzer

    International Nuclear Information System (INIS)

    Anderson, G.A.; Brackenbush, L.W.

    1993-06-01

    The instrumentation used in nuclear spectroscopy is generally large, is not portable, and requires a lot of power. Key components of these counting systems are the computer and the Multi-Channel Analyzer (MCA). To assist in performing measurements requiring portable systems, a small, very low power MCA has been developed at Pacific Northwest Laboratory (PNL). This MCA is interfaced with a Hewlett Packard palm top computer for portable applications. The MCA can also be connected to an IBM/PC for data storage and analysis. In addition, a real-time time display mode allows the user to view the spectra as they are collected

  7. A Novel Architecture For Multichannel Analyzer

    International Nuclear Information System (INIS)

    Marcus, E.; Elhanani, I.; Nir, J.; Ellenbogen, M.; Kadmon, Y.; Tirosh, D.

    1999-01-01

    A novel digital approach to real-time, high-throughput, low-cost Multichannel Analyzer (MCA) for radiation spectroscopy is being presented. The MCA input is a shaped nuclear pulse sampled at a high rate, using an Analog-to-Digital Converter (ADC) chip. The digital samples are analyzed by a state-of-the-art Field Programmable Gate Away (FPGA). A customized algorithm is utilized to estimate the peak of the pulse, to reject pile-up and to eliminate processing dead time. The valid pulses estimated peaks are transferred to a micro controller system that creates the histogram and controls the Human Machine Interface (HMI)

  8. Geometric beam coupling impedance of LHC secondary collimators

    Science.gov (United States)

    Frasciello, Oscar; Tomassini, Sandro; Zobov, Mikhail; Salvant, Benoit; Grudiev, Alexej; Mounet, Nicolas

    2016-02-01

    The High Luminosity LHC project is aimed at increasing the LHC luminosity by an order of magnitude. One of the key ingredients to achieve the luminosity goal is the beam intensity increase. In order to keep beam instabilities under control and to avoid excessive power losses a careful design of new vacuum chamber components and an improvement of the present LHC impedance model are required. Collimators are among the major impedance contributors. Measurements with beam have revealed that the betatron coherent tune shifts were higher by about a factor of 2 with respect to the theoretical predictions based on the LHC impedance model up to 2012. In that model the resistive wall impedance has been considered as the dominating impedance contribution for collimators. By carefully simulating also their geometric impedance we have contributed to the update of the LHC impedance model, reaching also a better agreement between the measured and simulated betatron tune shifts. During the just ended LHC Long Shutdown I (LSI), TCS/TCT collimators were replaced by new devices embedding BPMs and TT2-111R ferrite blocks. We present here preliminary estimations of their broad-band impedance, showing that an increase of about 20% is expected in the kick factors with respect to previous collimators without BPMs.

  9. Sound Propagation An impedance Based Approach

    CERN Document Server

    Kim, Yang-Hann

    2010-01-01

    In Sound Propagation: An Impedance Based Approach , Professor Yang-Hann Kim introduces acoustics and sound fields by using the concept of impedance. Kim starts with vibrations and waves, demonstrating how vibration can be envisaged as a kind of wave, mathematically and physically. One-dimensional waves are used to convey the fundamental concepts. Readers can then understand wave propagation in terms of characteristic and driving point impedance. The essential measures for acoustic waves, such as dB scale, octave scale, acoustic pressure, energy, and intensity, are explained. These measures are

  10. Multichannel analyzer for the neutron time-of-flight spectrometer

    International Nuclear Information System (INIS)

    Vojter, A.P.; Slyisenko, V.Yi.; Doronyin, M.Yi.; Maznij, Yi.O.; Vasil'kevich, O.A.; Golyik, V.V.; Koval'ov, O.M.; Kopachov, V.Yi.; Savchuk, V.G.

    2010-01-01

    New multichannel time-of-flight spectrometer for the measurement of the energy and angular distributions of neutrons from the WWWR-M reactor is considered. This spectrometer has been developed for the replacement of the previous one to increase the number of channels and measurement precision, reduce the time of channel tuning and provide the automatic monitoring during the experiment.

  11. A dialog program for the evaluation of multichannel spectra

    International Nuclear Information System (INIS)

    Dietze, G.

    1978-06-01

    The computer code SPEKT is described for the analysis and manipulation of multichannel spectra in neutron dosimetry. It is a dialog system with a simple command string. The code has mainly been written in FORTRAN. Because of the modular structure of the program a user can add new routines in a simple way. (orig./HP) [de

  12. Broadband electrical impedance matching for piezoelectric ultrasound transducers.

    Science.gov (United States)

    Huang, Haiying; Paramo, Daniel

    2011-12-01

    This paper presents a systematic method for designing broadband electrical impedance matching networks for piezoelectric ultrasound transducers. The design process involves three steps: 1) determine the equivalent circuit of the unmatched piezoelectric transducer based on its measured admittance; 2) design a set of impedance matching networks using a computerized Smith chart; and 3) establish the simulation model of the matched transducer to evaluate the gain and bandwidth of the impedance matching networks. The effectiveness of the presented approach is demonstrated through the design, implementation, and characterization of impedance matching networks for a broadband acoustic emission sensor. The impedance matching network improved the power of the acquired signal by 9 times.

  13. Light coupling and distribution for Si3N4/SiO2 integrated multichannel single-mode sensing system

    Science.gov (United States)

    Kaźmierczak, Andrzej; Dortu, Fabian; Schrevens, Olivier; Giannone, Domenico; Bouville, David; Cassan, Eric; Gylfason, Kristinn B.; Sohlström, Hans; Sanchez, Benito; Griol, Amadeu; Hill, Daniel

    2009-01-01

    We present an efficient and highly alignment-tolerant light coupling and distribution system for a multichannel Si3N4/SiO2 single-mode photonics sensing chip. The design of the input and output couplers and the distribution splitters is discussed. Examples of multichannel data obtained with the system are given.

  14. Ultrasmall and customizable multichannel electrodes for extracellular recordings.

    Science.gov (United States)

    Piironen, Arto; Weckström, Matti; Vähäsöyrinki, Mikko

    2011-03-01

    Increasing demand exists for smaller multichannel electrodes that enable simultaneous recordings of many neurons in a noninvasive manner. We report a novel method for manufacturing ultrasmall carbon fiber electrodes with up to seven closely spaced recording sites. The electrodes were designed to minimize damage to neuronal circuitry and to be fully customizable in three dimensions so that their dimensions can be optimally matched to those of the targeted neuron population.

  15. Regret of Multi-Channel Bandit Game in Cognitive Radio Networks

    Directory of Open Access Journals (Sweden)

    Ma Jun

    2016-01-01

    Full Text Available The problem of how to evaluate the rate of convergence to Nash equilibrium solutions in the process of channel selection under incomplete information is studied. In this paper, the definition of regret is used to reflect the convergence rates of online algorithms. The process of selecting an idle channel for each secondary user is modeled as a multi-channel bandit game. The definition of the maximal averaged regret is given. Two existing online learning algorithms are used to obtain the Nash equilibrium for each SU. The maximal averaged regrets are used to evaluate the performances of online algorithms. When there is a pure strategy Nash equilibrium in the multi-channel bandit game, the maximal averaged regrets are finite. A cooperation mechanism is also needed in the process of calculating the maximal averaged regrets. Simulation results show the maximal averaged regrets are finite and the online algorithm with greater convergence rate has less maximal averaged regrets.

  16. Car-borne multichannel gamma-ray spectrometric system model CZD-6

    International Nuclear Information System (INIS)

    Lu Shili; Zhai Yugui; Ma Yanfang; Jiao Cangwen; Zhang Biao

    1998-01-01

    The car-borne multichannel gamma-ray spectrometric system Mode CZD-6 is composed of a HDY-256 of portable multichannel gamma-ray spectrometer developed by the Beijing Research Institute of Uranium Geology and a large volume scintillation detector. the position for each measurement point is determined by the GPS instrument. Its latitude and longitude, as well as measured 256 channels of γ-spectrometric data are collected by a notebook computer, which can show the 256 channels of spectra for each point during measuring processes. The complete system can be loaded in a field car. This system has been used to environmental radioactive monitoring after calibration by airborne radiometric models in Shijiazhuang, Hebei province. A lot of data confirm that the system works stably and reliably, and is a fast and advanced approach for environmental γ-spectrometric monitoring. It can be used not only to determination of contents of natural radioactive elements in environments, but also to monitoring nuclear pollution and emergency treatment in nuclear accidents significantly

  17. Research on development of multi-channel analyzer used for monitoring and warning radiation equipment

    International Nuclear Information System (INIS)

    Nguyen Van Sy; Dang Quang Thieu; Nguyen Thi Bao My

    2015-01-01

    The subject assigned to this paper presents research on development of multi-channel analyzer used for monitoring and warning environmental radiation equipment under the project KC.05.16/11-15 Research on manufacturing equipment monitoring and warning radiation. In this thematic we have two subjects that need to be resolved such as: i) Designing spectroscopy amplifier block (AMP) duty pulse signals obtained about few hundred millivolts output from scintillation detector preamplifier, amplified as a few volts and the standard Gaussian pulses shaped to connect to the analog-to-digital converter. The spectroscopy amplifier block can change the gain by digital control to respond to the problem of automatic spectrum stability for multi-channel analyzer systems. ii) Designing analog-to-digital converter block (ADC) in accordance with the actual conditions, such as high stability, fast conversion time, high throughput, and it consumes low energy. Selecting suitable microprocessor for fast connection ability, to operate reliably paired with the analog-to-digital converter into a multi-channel analyzer (MCA) serving analysis. (author)

  18. Effect of Electrode Belt and Body Positions on Regional Pulmonary Ventilation- and Perfusion-Related Impedance Changes Measured by Electric Impedance Tomography.

    Directory of Open Access Journals (Sweden)

    Elin Ericsson

    Full Text Available Ventilator-induced or ventilator-associated lung injury (VILI/VALI is common and there is an increasing demand for a tool that can optimize ventilator settings. Electrical impedance tomography (EIT can detect changes in impedance caused by pulmonary ventilation and perfusion, but the effect of changes in the position of the body and in the placing of the electrode belt on the impedance signal have not to our knowledge been thoroughly evaluated. We therefore studied ventilation-related and perfusion-related changes in impedance during spontaneous breathing in 10 healthy subjects in five different body positions and with the electrode belt placed at three different thoracic positions using a 32-electrode EIT system. We found differences between regions of interest that could be attributed to changes in the position of the body, and differences in impedance amplitudes when the position of the electrode belt was changed. Ventilation-related changes in impedance could therefore be related to changes in the position of both the body and the electrode belt. Perfusion-related changes in impedance were probably related to the interference of major vessels. While these findings give us some insight into the sources of variation in impedance signals as a result of changes in the positions of both the body and the electrode belt, further studies on the origin of the perfusion-related impedance signal are needed to improve EIT further as a tool for the monitoring of pulmonary ventilation and perfusion.

  19. Efficacy of transoral intraluminal Wallstents for tracheal stenosis or tracheomalacia.

    Science.gov (United States)

    Casiano, R R; Numa, W A; Nurko, Y J

    2000-10-01

    The efficacy and safety of intraluminal Wallstent Endoprosthesis (Boston Scientific/ Medi-Tech, Quincy, MA) placement to restore airway patency in patients with tracheal stenosis or tracheomalacia are unknown. Retrospective review in setting of tertiary, referral, and academic center. A retrospective review of 13 consecutive patients over a 2-year period who underwent transoral resection of tracheal stenosis and immediate transoral Wallstent placement. One patient had tracheomalacia. All of the patients were considered at high risk for transcervical surgery or had failed prior traditional open procedures. The average patient age was 54.2 years, with nine male and four female patients. All had Cotton/Myer stenoses (grades II to IV) with moderate to severe degrees of inspiratory stridor. Four patients were tracheotomy dependent. The length of stenosis varied from 1 to 4 cm. One patient had a 10-cm segment of tracheomalacia. At the time of writing, none of the patients has had a problem with significant migration or extrusion and most of the patients have incorporated the stent well without any short-term obstructive granulation tissue. After a mean follow-up of 15 months (range, 4-24 mo). 10 of the 12 patients with stenosis (83%) have remained free of any inspiratory noise during breathing. The one patient with tracheomalacia also has remained free of symptoms. Transoral Wallstents appear to be safe and may be a reasonable alternative in the restoration of airway patency in select patients with tracheal stenosis or tracheomalacia.

  20. Novel Methods for Measuring Depth of Anesthesia by Quantifying Dominant Information Flow in Multichannel EEGs

    Directory of Open Access Journals (Sweden)

    Kab-Mun Cha

    2017-01-01

    Full Text Available In this paper, we propose novel methods for measuring depth of anesthesia (DOA by quantifying dominant information flow in multichannel EEGs. Conventional methods mainly use few EEG channels independently and most of multichannel EEG based studies are limited to specific regions of the brain. Therefore the function of the cerebral cortex over wide brain regions is hardly reflected in DOA measurement. Here, DOA is measured by the quantification of dominant information flow obtained from principle bipartition. Three bipartitioning methods are used to detect the dominant information flow in entire EEG channels and the dominant information flow is quantified by calculating information entropy. High correlation between the proposed measures and the plasma concentration of propofol is confirmed from the experimental results of clinical data in 39 subjects. To illustrate the performance of the proposed methods more easily we present the results for multichannel EEG on a two-dimensional (2D brain map.

  1. Multichannel fiber laser Doppler vibrometer studies of low momentum and hypervelocity impacts

    Science.gov (United States)

    Posada-Roman, Julio E.; Jackson, David A.; Cole, Mike J.; Garcia-Souto, Jose A.

    2017-12-01

    A multichannel optical fiber laser Doppler vibrometer was demonstrated with the capability of making simultaneous non-contact measurements of impacts at 3 different locations. Two sets of measurements were performed, firstly using small ball bearings (1 mm-5.5 mm) falling under gravity and secondly using small projectiles (1 mm) fired from an extremely high velocity light gas gun (LGG) with speeds in the range 1 km/s-8 km/s. Determination of impact damage is important for industries such as aerospace, military and rail, where the effect of an impact on the structure can result in a major structural damage. To our knowledge the research reported here demonstrates the first trials of a multichannel fiber laser Doppler vibrometer being used to detect hypervelocity impacts.

  2. Multichannel deconvolution and source detection using sparse representations: application to Fermi project

    International Nuclear Information System (INIS)

    Schmitt, Jeremy

    2011-01-01

    This thesis presents new methods for spherical Poisson data analysis for the Fermi mission. Fermi main scientific objectives, the study of diffuse galactic background et the building of the source catalog, are complicated by the weakness of photon flux and the point spread function of the instrument. This thesis proposes a new multi-scale representation for Poisson data on the sphere, the Multi-Scale Variance Stabilizing Transform on the Sphere (MS-VSTS), consisting in the combination of a spherical multi-scale transform (wavelets, curvelets) with a variance stabilizing transform (VST). This method is applied to mono- and multichannel Poisson noise removal, missing data interpolation, background extraction and multichannel deconvolution. Finally, this thesis deals with the problem of component separation using sparse representations (template fitting). (author) [fr

  3. Impedance interactions in bidirectional cascaded converter

    DEFF Research Database (Denmark)

    Tian, Yanjun; Loh, Poh Chiang; Chen, Zhe

    2016-01-01

    A cascaded converter is built by connecting one elementary converter to another. Output impedance of one converter will therefore interact with input impedance of the other converter. This interaction will change when power flow reverses. To compare this difference, an investigation is performed...

  4. Impedance of accelerator components

    International Nuclear Information System (INIS)

    Corlett, J.N.

    1996-05-01

    As demands for high luminosity and low emittance particle beams increase, an understanding of the electromagnetic interaction of these beams with their vacuum chamber environment becomes more important in order to maintain the quality of the beam. This interaction is described in terms of the wake field in time domain, and the beam impedance in frequency domain. These concepts are introduced, and related quantities such as the loss factor are presented. The broadband Q = 1 resonator impedance model is discussed. Perturbation and coaxial wire methods of measurement of real components are reviewed

  5. Y-Source Impedance Network

    DEFF Research Database (Denmark)

    Siwakoti, Yam Prasad; Loh, Poh Chiang; Blaabjerg, Frede

    2014-01-01

    This letter introduces a new versatile Y-shaped impedance network for realizing converters that demand a very high-voltage gain, while using a small duty ratio. To achieve that, the proposed network uses a tightly coupled transformer with three windings, whose obtained gain is presently not matched...... by existing networks operated at the same duty ratio. The proposed impedance network also has more degrees of freedom for varying its gain, and hence, more design freedom for meeting requirements demanded from it. This capability has been demonstrated by mathematical derivation, and proven in experiment...

  6. A Receiver-Initiated Collision-Avoidance Protocol for Multi-Channel Networks

    Science.gov (United States)

    2001-01-01

    00-00-2001 to 00-00-2001 4. TITLE AND SUBTITLE A Receiver-Initiated Collision-Avoidance Protocol for Multi-Channel Netowrks 5a. CONTRACT NUMBER...images. 14. ABSTRACT 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF PAGES 10 19a. NAME OF RESPONSIBLE

  7. An optimal multi-channel memory controller for real-time systems

    NARCIS (Netherlands)

    Gomony, M.D.; Akesson, K.B.; Goossens, K.G.W.

    2013-01-01

    Optimal utilization of a multi-channel memory, such as Wide IO DRAM, as shared memory in multi-processor platforms depends on the mapping of memory clients to the memory channels, the granularity at which the memory requests are interleaved in each channel, and the bandwidth and memory capacity

  8. The designing principle and implementation of multi-channel intelligence isotope thickness gauge based on multifunction card PCI-1710

    International Nuclear Information System (INIS)

    Zhang Bin; Zhao Shujun; Guo Maotian; He Jintian

    2006-01-01

    The designing principle, the constitution of system and the implementation of multi-channel intelligence isotope thickness gauge are introduced in the paper in detail, which are based on multifunction card PCI-1710. The paper also discusses the primaryprinciple of isotope thickness gauge, correct factor in measurement and complication of calibration. In the following, the whole frame of multi-channel intelligence isotope thickness gauge is given. The functions, the characteristics and the usage of multifunction card PCI-1710 are described. Furthermore, the developing process and the function modules of software are presented. Finally, the real prototype of multi-channel intelligence isotope thickness gauge is introduced, using 241 Am as a radioactive element. (authors)

  9. MVAC Submarine cable, impedance measurements and analysis

    DEFF Research Database (Denmark)

    Arentsen, Martin Trolle; Expethit, Adrian; Pedersen, Morten Virklund

    2017-01-01

    influence the losses. Secondly, cable parameters such as component impedances, positive-, zero-sequence impedances and losses are measured for varying currents and frequencies. Zero sequence is measured for two setups, one with armour grounded, and with armour open to match CIGREs formula assumption......-sequence impedance is found between the measurements and the CIGRÉ formulas. It is concluded that the formulas are not accurate for the specific cable under test....

  10. Multichannel Seismic Reflection - SCAR- Prydz Bay 1980 SDLS CD-ROM vol 8

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data recorded during 1980 in the Prydz Bay region, by Australian Geological Survey Organization. The...

  11. A novel portable multi-channel analyzer based on high-speed microcontroller

    International Nuclear Information System (INIS)

    Lou Xinghua; Yi Hongchang; Wang Yuemin

    2005-01-01

    This paper introduces a novel portable multi-channel analyzer (MCA) based on high-speed microcontroller. The hardware implementation and the software scenario of the MCA are discussed. The MCA has features of high speed, small size and better performances. (authors)

  12. PHEMT Distributed Power Amplifier Adopting Broadband Impedance Transformer

    DEFF Research Database (Denmark)

    Narendra, K.; Limiti, E.; Paoloni, C.

    2013-01-01

    A non-uniform drain line distributed power amplifier (DPA) employing a broadband impedance transformer is presented. The DPA is based on GaAs PHEMT technology. The impedance transformer employs asymmetric coupled lines and transforms a low output impedance of the amplifier to a standard 50 Ω...

  13. Optical approximation in the theory of geometric impedance

    International Nuclear Information System (INIS)

    Stupakov, G.; Bane, K.L.F.; Zagorodnov, I.

    2007-02-01

    In this paper we introduce an optical approximation into the theory of impedance calculation, one valid in the limit of high frequencies. This approximation neglects diffraction effects in the radiation process, and is conceptually equivalent to the approximation of geometric optics in electromagnetic theory. Using this approximation, we derive equations for the longitudinal impedance for arbitrary offsets, with respect to a reference orbit, of source and test particles. With the help of the Panofsky-Wenzel theorem we also obtain expressions for the transverse impedance (also for arbitrary offsets). We further simplify these expressions for the case of the small offsets that are typical for practical applications. Our final expressions for the impedance, in the general case, involve two dimensional integrals over various cross-sections of the transition. We further demonstrate, for several known axisymmetric examples, how our method is applied to the calculation of impedances. Finally, we discuss the accuracy of the optical approximation and its relation to the diffraction regime in the theory of impedance. (orig.)

  14. A multichannel smartphone optical biosensor for high-throughput point-of-care diagnostics.

    Science.gov (United States)

    Wang, Li-Ju; Chang, Yu-Chung; Sun, Rongrong; Li, Lei

    2017-01-15

    Current reported smartphone spectrometers are only used to monitor or measure one sample at a time. For the first time, we demonstrate a multichannel smartphone spectrometer (MSS) as an optical biosensor that can simultaneously optical sense multiple samples. In this work, we developed a novel method to achieve the multichannel optical spectral sensing with nanometer resolution on a smartphone. A 3D printed cradle held the smartphone integrated with optical components. This optical sensor performed accurate and reliable spectral measurements by optical intensity changes at specific wavelength or optical spectral shifts. A custom smartphone multi-view App was developed to control the optical sensing parameters and to align each sample to the corresponding channel. The captured images were converted to the transmission spectra in the visible wavelength range from 400nm to 700nm with the high resolution of 0.2521nm per pixel. We validated the performance of this MSS via measuring the concentrations of protein and immunoassaying a type of human cancer biomarker. Compared to the standard laboratory instrument, the results sufficiently showed that this MSS can achieve the comparative analysis detection limits, accuracy and sensitivity. We envision that this multichannel smartphone optical biosensor will be useful in high-throughput point-of-care diagnostics with its minimizing size, light weight, low cost and data transmission function. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Multi-channel fiber optic dew and humidity sensor

    Science.gov (United States)

    Limodehi, Hamid E.; Mozafari, Morteza; Amiri, Hesam; Légaré, François

    2018-03-01

    In this article, we introduce a multi-channel fiber optic dew and humidity sensor which works using a novel method based on relation between surface plasmon resonance (SPR) and water vapor condensation. The proposed sensor can instantly detect moisture or dew formation through its fiber optic channels, separately situated in different places. It enables to simultaneously measure the ambient Relative Humidity (RH) and dew point temperature of several environments with accuracy of 5%.

  16. Multichannel far-infrared phase imaging for fusion plasmas

    International Nuclear Information System (INIS)

    Young, P.E.; Neikirk, D.P.; Tong, P.P.; Rutledge, D.B.; Luhmann, N.C. Jr.

    1985-01-01

    A 20-channel far-infrared imaging interferometer system has been used to obtain single-shot density profiles in the UCLA Microtor tokamak. This system differs from conventional multichannel interferometers in that the phase distribution produced by the plasma is imaged onto a single, monolithic, integrated microbolometer linear detector array and provides significantly more channels than previous far-infrared interferometers. The system has been demonstrated to provide diffraction-limited phase images of dielectric targets

  17. FDTD modeling of thin impedance sheets

    Science.gov (United States)

    Luebbers, Raymond J.; Kunz, Karl S.

    1991-01-01

    Thin sheets of resistive or dielectric material are commonly encountered in radar cross section calculations. Analysis of such sheets is simplified by using sheet impedances. In this paper it is shown that sheet impedances can be modeled easily and accurately using Finite Difference Time Domain (FDTD) methods.

  18. Quadratic Boost A-Source Impedance Network

    DEFF Research Database (Denmark)

    Siwakoti, Yam Prasad; Blaabjerg, Frede; Chub, Andrii

    2016-01-01

    A novel quadratic boost A-source impedance network is proposed to realize converters that demand very high voltage gain. To satisfy the requirement, the network uses an autotransformer where the obtained gain is quadratically dependent on the duty ratio and is unmatched by any existing impedance...

  19. Multichannel Seismic Reflection Data, SCAR - Wilkes Land 1982, SDLS, CD-ROM 15

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data from thirteen lines recorded during 1983 off Wilkes Island, Antarctica, by the U.S. Geological...

  20. Microfluidic device for cell capture and impedance measurement.

    Science.gov (United States)

    Jang, Ling-Sheng; Wang, Min-How

    2007-10-01

    This work presents a microfluidic device to capture physically single cells within microstructures inside a channel and to measure the impedance of a single HeLa cell (human cervical epithelioid carcinoma) using impedance spectroscopy. The device includes a glass substrate with electrodes and a PDMS channel with micro pillars. The commercial software CFD-ACE+ is used to study the flow of the microstructures in the channel. According to simulation results, the probability of cell capture by three micro pillars is about 10%. An equivalent circuit model of the device is established and fits closely to the experimental results. The circuit can be modeled electrically as cell impedance in parallel with dielectric capacitance and in series with a pair of electrode resistors. The system is operated at low frequency between 1 and 100 kHz. In this study, experiments show that the HeLa cell is successfully captured by the micro pillars and its impedance is measured by impedance spectroscopy. The magnitude of the HeLa cell impedance declines at all operation voltages with frequency because the HeLa cell is capacitive. Additionally, increasing the operation voltage reduces the magnitude of the HeLa cell because a strong electric field may promote the exchange of ions between the cytoplasm and the isotonic solution. Below an operating voltage of 0.9 V, the system impedance response is characteristic of a parallel circuit at under 30 kHz and of a series circuit at between 30 and 100 kHz. The phase of the HeLa cell impedance is characteristic of a series circuit when the operation voltage exceeds 0.8 V because the cell impedance becomes significant.

  1. A new method for multi-channel Fabry-Perot spectroscopy of light pulses in the nanosecond regime

    International Nuclear Information System (INIS)

    Behn, R.

    1975-01-01

    The demand for powerful multichannel spectrometers raised, e.g., in laser scattering plasma diagnostics, gave rise to the question if it would not be possible to avoid the light losses occuring in the use of multichannel Fabry-Perot spectrometers. These losses can be avoided with the technique presented here. The reflected light is collected and fed back to the interferometer at a different angle. It can thus be recovered for registration in another spectral channel. This method is particularly suitable for the investigation of short light pulses. A spectrum can thus be scanned step by step with full utilization of the transit time of the light pulse. In addition to light recovery, there is another advantage in that only one detector is used for multichannel analysis, thus eliminating calibration problems. In the annex to the report, emission spectres of different dye laser versions are presented and explained. (orig./GG) [de

  2. Local impedance measurement of an electrode/single-pentacene-grain interface by frequency-modulation scanning impedance microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Kimura, Tomoharu; Yamada, Hirofumi, E-mail: h-yamada@kuee.kyoto-u.ac.jp [Department of Electronic Science and Engineering, Kyoto University, Kyoto 615-8510 (Japan); Kobayashi, Kei [Department of Electronic Science and Engineering, Kyoto University, Kyoto 615-8510 (Japan); The Hakubi Center for Advanced Research, Kyoto University, Kyoto 615-8520 (Japan)

    2015-08-07

    The device performances of organic thin film transistors are often limited by the metal–organic interface because of the disordered molecular layers at the interface and the energy barriers against the carrier injection. It is important to study the local impedance at the interface without being affected by the interface morphology. We combined frequency modulation atomic force microscopy with scanning impedance microscopy (SIM) to sensitively measure the ac responses of the interface to an ac voltage applied across the interface and the dc potential drop at the interface. By using the frequency-modulation SIM (FM-SIM) technique, we characterized the interface impedance of a Pt electrode and a single pentacene grain as a parallel circuit of a contact resistance and a capacitance. We found that the reduction of the contact resistance was caused by the reduction of the energy level mismatch at the interface by the FM-SIM measurements, demonstrating the usefulness of the FM-SIM technique for investigation of the local interface impedance without being affected by its morphology.

  3. Intraluminal brachytherapy in carcinoma of the oesophagus: comparison of afterloading techniques

    International Nuclear Information System (INIS)

    Udaya Kumar, M.; Supe, S.S.; Swamy, Kumara; Keshava, S.L.; Anantha, N.

    1993-01-01

    For improved local control or palliation of oesophageal cancers, intra-luminal brachytherapy (ILB) has emerged as an increasingly popular treatment modality of therapy in recent years. In combination with external radiotherapy, after-loaded ILB can increase local control rates and may prolong survival of these patients. In this paper two techniques of ILB viz., manual and low dose-rate remote after loading methods, using caesium-137 tubes and pellets respectively, are described in detail. On comparison of these two techniques it was found that both of them were similar with respect to their physical characteristic (dose rate, dose fall-off, maximum spinal cord dose, total reference air kerma, etc.). Clinically, the manual after-loaded ILB technique was found to be easier to use when compared with the low-dose rate remote after-loader. In addition, the number of patients with uterine cancers being high in a developing country, it was found that it was inappropriate to use the low dose remote after-loaders, designed for use in gynaecological cancers, for ILB of oesophageal cancers. Therefore, in the absence of high dose rate after-loaders, which can be utilized for intracavitary treatments of both uterine and oesophageal malignancies effectively, the manual after-loading ILB system as described in this paper could be a practical alternative. (author). 19 refs., 4 figs., 2 tabs

  4. MHD flow in multichannel U-bends: Screening experiments and theoretical analysis

    International Nuclear Information System (INIS)

    Reimann, J.; Molokov, S.; Platnieks, I.; Platacis, E.

    1993-02-01

    In electrically coupled multichannel ducts with a U-bend geometry magnetohydrodynamic effects are expected to cause strongly ununiform distributions of flow rates Q i and pressure drops Δp i in the individual channels. A multichannel U-bend geometry is part of the KfK self-cooled Pb-17 Li blanket design (radial-toroidal-radial channels). However, inserts are proposed which isolate electrically the radial channels (not the toroidal ones). To investigate the multichannel effect (MCE), screening experiments were performed at LAS, Riga, with different flow channel geometries and channel numbers between 1 and 5 and using InGaSn as liquid metal. These experiments were carried out with either Δp i ∼const or Q i ∼const. Hartmann Numbers were varied between 0 and ∼1600 (maximum magnetic field strength: 4.1 T) and Interaction Parameters between 0 and 10000. For experiments with electrically conducting walls between the channels, the volume flow rates in the outer channels are significantly larger than those in the inner channels in the experiments with Δp i ∼const. For Q i ∼const., this tendency is reversed, with the highest pressure drop in the middle channel and the lowest in the outer channels. The flow geometry with electrically separated radial channels, similar to the KfK-design result in a fairly even flow rate and pressure drop distribution. The single channels behave approximately like electrically separated channels; no marked MCE occurrs. A theoretical analysis was carried out to describe the MCE for the multichannel U-bend with thin electrically conducting outside walls. This analysis is based on the Core Flow Approximation (CFA), valid for infinitely large Interaction Parameters and Hartmann Numbers. The theory predicts correctly all tendencies observed for the pressure measurements. Moreover, the method is able to describe in detail the flow structure in the toroidal channel. The most essential result is that the flow rate in the layer close to the

  5. Impedance coordinative control for cascaded converter in bidirectional application

    DEFF Research Database (Denmark)

    Tian, Yanjun; Loh, Poh Chiang; Deng, Fujin

    2016-01-01

    A two-stage cascaded converter is formed by connecting two sub-converters in series. Output impedance of one sub-converter will therefore interact with input impedance of the other sub-converter. Such interaction may affect the system dynamics and stability, especially when one sub......-converter is constant-power-controlled, and hence has different impedance characteristics when its power reverses. To lessen such constant-power effects, a control scheme that can coordinate impedance behaviors of the two sub-converters is proposed. The idea is to reshape the lowfrequency negative impedance...

  6. Multichannel approach to studying scalar resonances

    International Nuclear Information System (INIS)

    Krupa, D.; Surovtsev, Yu.S.

    1995-11-01

    The multichannel approach to the investigation of resonances is given in order to determine their quantum chromodynamical nature. The formula for the analytic continuation of the N-channel S-matrix to the unphysical sheets of the Riemann surface is given, which is a solution of the N-channel problem in that it enables a prediction of the coupled-process amplitudes on the uniformization plane of the S-matrix. The resonance representations by pairs of complex-conjugate clusters of poles and zeros on the Riemann surface are discussed. The concept of standard clusters as model-independent characteristics of the resonance is developed. 32 refs, 5 figs, 4 tabs

  7. Multichannel Baseband Processor for Wideband CDMA

    Science.gov (United States)

    Jalloul, Louay M. A.; Lin, Jim

    2005-12-01

    The system architecture of the cellular base station modem engine (CBME) is described. The CBME is a single-chip multichannel transceiver capable of processing and demodulating signals from multiple users simultaneously. It is optimized to process different classes of code-division multiple-access (CDMA) signals. The paper will show that through key functional system partitioning, tightly coupled small digital signal processing cores, and time-sliced reuse architecture, CBME is able to achieve a high degree of algorithmic flexibility while maintaining efficiency. The paper will also highlight the implementation and verification aspects of the CBME chip design. In this paper, wideband CDMA is used as an example to demonstrate the architecture concept.

  8. Line impedance estimation using model based identification technique

    DEFF Research Database (Denmark)

    Ciobotaru, Mihai; Agelidis, Vassilios; Teodorescu, Remus

    2011-01-01

    The estimation of the line impedance can be used by the control of numerous grid-connected systems, such as active filters, islanding detection techniques, non-linear current controllers, detection of the on/off grid operation mode. Therefore, estimating the line impedance can add extra functions...... into the operation of the grid-connected power converters. This paper describes a quasi passive method for estimating the line impedance of the distribution electricity network. The method uses the model based identification technique to obtain the resistive and inductive parts of the line impedance. The quasi...

  9. Modelling a coal subcrop using the impedance method

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, G.A.; Thiel, D.V.; O' Keefe, S.G. [Griffith University, Nathan, Qld. (Australia). School of Microelectronic Engineering

    2000-07-01

    An impedance model was generated for two coal subcrops in the Biloela and Middlemount areas (Queensland, Australia). The model results were compared with actual surface impedance data. It was concluded that the impedance method satisfactorily modelled the surface response of the coal subcrops in two dimensions. There were some discrepancies between the field data and the model results, due to factors such as the method of discretization of the solution space in the impedance model and the lack of consideration of the three-dimensional nature of the coal outcrops. 10 refs., 8 figs.

  10. Gastro-Oesophageal Reflux and Apnoea: Is There a Temporal Relationship?

    Science.gov (United States)

    Rossor, Thomas; Andradi, Gwendolyn; Ali, Kamal; Bhat, Ravindra; Greenough, Anne

    2018-01-01

    Gastro-oesophageal reflux (GOR) and apnoea are common in infants; whether there is a causal relationship is controversial. To determine whether there was a temporal relationship between GOR and apnoea, in particular, the frequency of obstructive apnoeas and if the frequency of GOR episodes correlated with apnoea frequency when maturity at testing was taken into account. Polysomnography and pH/multichannel intraluminal impedance (MII) studies were performed. Apnoeas were classified as central, obstructive, or mixed. MII events were classified as acidic (pH reflux event was compared to that in the 5-min period preceding the event and that in a 5-min reflux-free period (control period). Forty infants (median gestational age 29 [range 24-42] weeks) were assessed at a post-conceptional age of 37 (30-54) weeks. Obstructive (n = 580), central (n = 900), and mixed (n = 452) apnoeas were identified; 381 acid reflux events were detected by MII and 153 by the pH probe only. Apnoeas were not more frequent following GOR than during control periods. Both the frequency of apnoeas (p = 0.002) and GOR episodes (p = 0.01) were inversely related to post-conceptional age at testing, but were not significantly correlated with each other when controlled for post-conceptional age. These results suggest that GOR does not cause apnoea. © 2017 S. Karger AG, Basel.

  11. Gastroesophageal flap valve reflected EGJ morphology and correlated to acid reflux.

    Science.gov (United States)

    Xie, Chenxi; Li, Yuwen; Zhang, Ning; Xiong, Lishou; Chen, Minhu; Xiao, Yinglian

    2017-11-22

    The anatomy of esophagogastric junction (EGJ) serves as the anti-reflux barrier. The gastroesophageal flap valve (GEFV) is a component of EGJ. The aim of the current study was to assess its correlation with the esophageal acid exposure and the impact on anti-reflux barrier function by using the metrics of EGJ contraction. Eighty three patients with typical GERD symptoms were included in the study. Upper endoscopy, high-resolution manometry (HRM) and 24 h multichannel intraluminal impedance-pH (MII-pH) monitoring were performed in all patients. GEFV was determined as four grades during endoscopic examination based on the Hill classification. The esophageal pressure topography (EPT) metrics defined in the updated Chicago Classification were measured by HRM, including integrated relaxation pressure (IRP), EGJ contractile index (EGJ-CI),expiratory EGJ pressure(EGJP-exp) and inspiratory EGJ pressure (EGJP-insp). The GEFV grade III and IV was more commonly found in patients with esophagitits (p acid exposure time (AET%) and supine AET% were lower in patients with GEFV grade I (p  0.05). The GEFV grades were associated with acid reflux positively and could be a good reflection of EGJ morphology in HRM. But it had no impact on the four HRM metrics. Our research revealed that GEFV may play an assistant role in the anti-reflux barrier.

  12. Do laryngoscopic findings reflect the characteristics of reflux in patients with laryngopharyngeal reflux?

    Science.gov (United States)

    Lee, Y C; Kwon, O E; Park, J M; Eun, Y G

    2018-02-01

    To analyse the association between 24-hour multichannel intraluminal impedance-pH (24-h MII-pH) parameters and each item of the reflux finding score (RFS) to determine whether the laryngoscopic findings of the RFS could reflect the characteristics of reflux in patients with laryngopharyngeal reflux (LPR). Prospective cohort study. Tertiary care referral medical centre. Patients complaining of LPR symptoms were evaluated via a 24-hour MII-pH. Among them, 99 patients whose LPR was confirmed via 24-hour MII-pH were enrolled in this study. Correlations between RFS ratings and 24-hour MII-pH parameters were evaluated and compared between patients with or without each laryngoscopic finding used in the RFS. Subglottic oedema had a statistically significant positive correlation with number of non-acid LPR and non-acid full column reflux events. Ventricular obliteration and posterior commissure hypertrophy showed a significant correlation with non-acid exposure time and total reflux exposure time. We also found a significant correlation between granuloma/granulation score and number of acid LPR events. The numbers of non-acid LPR and full column reflux events in patients with subglottic oedema were significantly higher than those without subglottic oedema. Among the laryngoscopic findings used in the RFS, subglottic oedema is specific for non-acid reflux episodes, and granuloma/granulation is specific for acid reflux episodes. © 2017 John Wiley & Sons Ltd.

  13. Transverse Impedance Model of the CERN-PSB

    OpenAIRE

    Zannini, Carlo; Iadarola, Giovanni; Jones, Bryan; Li, Kevin; Rijoff, Tatiana; Rumolo, Giovanni

    2015-01-01

    In the framework of the PS-Booster upgrade project an accurate impedance model is needed in order to determine the effect on the beam stability and assess the impact of the new devices before installation in the machine. This paper describes the PSB impedance model which includes resistive wall, indirect space charge, flanges, step transitions, ejection kicker including cables, injection kickers and cavities. Each impedance contribution has been computed for different energies in the PSB cycl...

  14. Impedance Spectroscopy of Dielectrics and Electronic Conductors

    DEFF Research Database (Denmark)

    Bonanos, Nikolaos; Pissis, Polycarpos; Macdonald, J. Ross

    2013-01-01

    Impedance spectroscopy is used for the characterization of materials, such as electroceramics, solid and liquid electrochemical cells, dielectrics and also fully integrated devices, such as fuel cells. It consists of measuring the electrical impedance - or a closely related property, such as admi......Impedance spectroscopy is used for the characterization of materials, such as electroceramics, solid and liquid electrochemical cells, dielectrics and also fully integrated devices, such as fuel cells. It consists of measuring the electrical impedance - or a closely related property......, such as admittance or dielectric constant - as a function of frequency and comparing the results with expectations based on physical, chemical, and microstructural models. This article reviews the principles and practical aspects of the technique, the representations of the results, the analysis of data......, and procedures for the correction of measurement errors. The applications of impedance spectroscopy are illustrated with examples from electroceramics and polymer-based dielectric systems. The way in which the technique is applied to the two classes of materials is compared with reference to the different models...

  15. Broadband impedance of the NESTOR storage ring

    International Nuclear Information System (INIS)

    Androsov, V.P.; Gladkikh, P.I.; Gvozd, A.M.; Karnaukhov, I.M.; Telegin, Yu.N.

    2011-01-01

    The contributions from lossy and inductive vacuum chamber components to the broadband impedance of the NESTOR storage ring are obtained by using both low-frequency analytical approaches and computer simulations. As was expected considering the small ring circumference (15.44m), the main contributions both to the longitudinal impedance Z || /n and the loss factor k loss come from the RF-cavity. Cavity impedance was also estimated with CST Microwave Studio (CST Studio Suite TM 2006) by simulating coaxial wire method commonly used for impedance measurements. Both estimates agree well. Finally, we performed the simulations of a number of inductive elements with CST Particle Studio 2010 by using wake field solver. We have also evaluated the bunch length in NESTOR taking the conservative estimate of 3 Ohm for the ring broadband impedance and have found that the bunch length s z = 0.5 cm could be obtained in steady state operation mode for the designed bunch current of 10 mA and RF-voltage of 250 kV.

  16. Advanced impedance modeling of solid oxide electrochemical cells

    DEFF Research Database (Denmark)

    Graves, Christopher R.; Hjelm, Johan

    2014-01-01

    Impedance spectroscopy is a powerful technique for detailed study of the electrochemical and transport processes that take place in fuel cells and electrolysis cells, including solid oxide cells (SOCs). Meaningful analysis of impedance measurements is nontrivial, however, because a large number...... techniques to provide good guesses for the modeling parameters, like transforming the impedance data to the distribution of relaxation times (DRT), together with experimental parameter sensitivity studies, is the state-of-the-art approach to achieve good EC model fits. Here we present new impedance modeling...... electrode and 2-D gas transport models which have fewer unknown parameters for the same number of processes, (ii) use of a new model fitting algorithm, “multi-fitting”, in which multiple impedance spectra are fit simultaneously with parameters linked based on the variation of measurement conditions, (iii...

  17. Scanning Multichannel Microwave Radiometer (SMMR) Monthly Mean Atmospheric Liquid Water (ALW) By Prabhakara

    Data.gov (United States)

    National Aeronautics and Space Administration — SMMR_ALW_PRABHAKARA data are Special Multichannel Microwave Radiometer (SMMR) Monthly Mean Atmospheric Liquid Water (ALW) data by Prabhakara.The Prabhakara Scanning...

  18. The impact of the multi-channel retail mix on online store choice: Does online experience matter?

    OpenAIRE

    Melis, Kristina; Campo, Katia; Breugelmans, Els; Lamey, Lien

    2015-01-01

    More and more grocery retailers are becoming multi-channel retailers, as they are opening an online alternative next to their traditional offline supermarkets. While the number of multi-channel grocery shoppers is also expanding at a fast growth rate, there are still large differences in online shopping frequency, and as a result, in the levels of experience with buying in the online grocery channel. This study wants to (i) identify the underlying drivers of online store choice and (ii) explo...

  19. Objective ARX Model Order Selection for Multi-Channel Human Operator Identification

    NARCIS (Netherlands)

    Roggenkämper, N; Pool, D.M.; Drop, F.M.; van Paassen, M.M.; Mulder, M.

    2016-01-01

    In manual control, the human operator primarily responds to visual inputs but may elect to make use of other available feedback paths such as physical motion, adopting a multi-channel control strategy. Hu- man operator identification procedures generally require a priori selection of the model

  20. Determination of beam coupling impedance in the frequency domain

    Energy Technology Data Exchange (ETDEWEB)

    Niedermayer, Uwe

    2016-07-01

    The concept of beam coupling impedance describes the electromagnetic interaction of uniformly moving charged particles with their surrounding structures in the Frequency Domain (FD). In synchrotron accelerators, beam coupling impedances can lead to beam induced component heating and coherent beam instabilities. Thus, in order to ensure the stable operation of a synchrotron, its impedances have to be quantified and their effects have to be controlled. Nowadays, beam coupling impedances are mostly obtained by Fourier transform of wake potentials, which are the results of Time Domain (TD) simulations. However, at low frequencies, low beam velocity, or for dispersive materials, TD simulations become unhandy. In this area, analytical calculations of beam coupling impedance in the FD, combined with geometry approximations, are still widely used. This thesis describes the development of two electromagnetic field solvers to obtain the beam coupling impedance directly in the FD, where the beam velocity is only a parameter and dispersive materials can be included easily. One solver is based on the Finite Integration Technique (FIT) on a staircase mesh. It is implemented both in 2D and 3D. However, the staircase mesh is inefficient on curved structures, which is particularly problematic for the modeling of a dipole source, that is required for the computation of the transverse beam coupling impedance. This issue is overcome by the second solver developed in this thesis, which is based on the Finite Element Method (FEM) on an unstructured triangular mesh. It is implemented in 2D and includes an optional Surface Impedance Boundary Condition (SIBC). Thus, it is well suited for the computation of longitudinal and transverse impedances of long beam pipe structures of arbitrary cross-section. Besides arbitrary frequency and beam velocity, also dispersive materials can be chosen, which is crucial for the computation of the impedance of ferrite kicker magnets. Numerical impedance

  1. 3D Multi-Channel Networked Visualization System for National LambdaRail, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Multichannel virtual reality visualization is the future of complex simulation with a large number of visual channels rendered and transmitted over high-speed...

  2. Calibration OGSE for a multichannel radiometer for Mars atmosphere studies

    Science.gov (United States)

    Jiménez, J. J.; Álvarez, F. J.; Gonzalez-Guerrero, M.; Apéstigue, V.; Martin, I.; Fernández, J. M.; Fernán, A. A.; Arruego, I.

    2017-09-01

    This work describes several OGSEs (Optical Ground Support Equipment) developed by INTA (Spanish Institute of Aerospace Technology - Instituto Nacional de Técnica Aeroespacial) for the calibration and characterization of their self-manufactured multichannel radiometers (Solar Irradiance Sensors - SIS) for planetary atmospheric studies in the frame of some Martian missions at which INTA is participating.

  3. ON SCALAR MESONS FROM THE COMBINED ANALYSIS OF MULTI-CHANNEL pi pi SCATTERING AND J/psi DECAYS

    Czech Academy of Sciences Publication Activity Database

    Surovtsev, Yu .S.; Bydžovský, Petr; Gutsche, T.; Lyubovitskij, V. E.

    2011-01-01

    Roč. 26, 3-4 (2011), s. 610-612 ISSN 0217-751X. [11th International Workshop on Meson Production , Properties and Interaction. Krakow, 10.06.2010-15.06.2010] R&D Projects: GA ČR GA202/08/0984 Institutional research plan: CEZ:AV0Z10480505 Keywords : Multi-channel pion-pion scattering * scalar-isoscalar resonances * multichannel analysis Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders Impact factor: 1.053, year: 2011

  4. Loudspeaker impedance emulator for multi resonant systems

    DEFF Research Database (Denmark)

    Iversen, Niels Elkjær; Knott, Arnold

    2015-01-01

    Specifying the performance of audio amplifiers is typically done by playing sine waves into a pure ohmic load. However real loudspeaker impedances are not purely ohmic but characterised by its electrical, mechanical and acoustical properties. Therefore a loudspeaker emulator capable of adjusting...... its impedance to that of a given loudspeaker is desired for measurement purposes. An adjustable RLC based emulator is implemented with switch controlled capacitors, air gap controlled inductors and potentiometers. Calculations and experimental results are compared and show that it is possible...... to emulate the loudspeaker impedance infinite baffle-, closed box- and the multi resonant vented box-loudspeaker by tuning the component values in the proposed circuit. Future work is outlined and encourage that the proposed impedance emulator is used as part of a control circuit in a switch-mode based...

  5. Metasurface for multi-channel terahertz beam splitters and polarization rotators

    Science.gov (United States)

    Zang, XiaoFei; Gong, HanHong; Li, Zhen; Xie, JingYa; Cheng, QingQing; Chen, Lin; Shkurinov, Alexander P.; Zhu, YiMing; Zhuang, SongLin

    2018-04-01

    Terahertz beam splitters and polarization rotators are two typical devices with wide applications ranging from terahertz communication to system integration. However, they are faced with severe challenges in manipulating THz waves in multiple channels, which is desirable for system integration and device miniaturization. Here, we propose a method to design ultra-thin multi-channel THz beam splitters and polarization rotators simultaneously. The reflected beams are divided into four beams with nearly the same density under illumination of linear-polarized THz waves, while the polarization of reflected beams in each channel is modulated with a rotation angle or invariable with respect to the incident THz waves, leading to the multi-channel polarization rotator (multiple polarization rotation in the reflective channels) and beam splitter, respectively. Reflective metasurfaces, created by patterning metal-rods with different orientations on a polyimide film, were fabricated and measured to demonstrate these characteristics. The proposed approach provides an efficient way of controlling polarization of THz waves in various channels, which significantly simplifies THz functional devices and the experimental system.

  6. An expert panel-based study on recognition of gastro-esophageal reflux in difficult esophageal pH-impedance tracings.

    Science.gov (United States)

    Smits, M J; Loots, C M; van Wijk, M P; Bredenoord, A J; Benninga, M A; Smout, A J P M

    2015-05-01

    Despite existing criteria for scoring gastro-esophageal reflux (GER) in esophageal multichannel pH-impedance measurement (pH-I) tracings, inter- and intra-rater variability is large and agreement with automated analysis is poor. To identify parameters of difficult to analyze pH-I patterns and combine these into a statistical model that can identify GER episodes with an international consensus as gold standard. Twenty-one experts from 10 countries were asked to mark GER presence for adult and pediatric pH-I patterns in an online pre-assessment. During a consensus meeting, experts voted on patterns not reaching majority consensus (>70% agreement). Agreement was calculated between raters, between consensus and individual raters, and between consensus and software generated automated analysis. With eight selected parameters, multiple logistic regression analysis was performed to describe an algorithm sensitive and specific for detection of GER. Majority consensus was reached for 35/79 episodes in the online pre-assessment (interrater κ = 0.332). Mean agreement between pre-assessment scores and final consensus was moderate (κ = 0.466). Combining eight pH-I parameters did not result in a statistically significant model able to identify presence of GER. Recognizing a pattern as retrograde is the best indicator of GER, with 100% sensitivity and 81% specificity with expert consensus as gold standard. Agreement between experts scoring difficult impedance patterns for presence or absence of GER is poor. Combining several characteristics into a statistical model did not improve diagnostic accuracy. Only the parameter 'retrograde propagation pattern' is an indicator of GER in difficult pH-I patterns. © 2015 John Wiley & Sons Ltd.

  7. Impedance of a slotted-pipe kicker

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Feng [Academia Sinica, Beijing, BJ (China). Inst. of High Energy Physics

    1996-08-01

    This paper introduces the principle of a new slotted kicker simply, which is made by using vacuum pipe itself with proper slits as current conductors, and then, presents a rough estimation of its longitudinal and transverse impedance, respectively. Calculation shows that its impedance is reduced significantly compared to our present air-coil kicker. (author)

  8. Impedance-matched Marx generators

    Directory of Open Access Journals (Sweden)

    W. A. Stygar

    2017-04-01

    Full Text Available We have conceived a new class of prime-power sources for pulsed-power accelerators: impedance-matched Marx generators (IMGs. The fundamental building block of an IMG is a brick, which consists of two capacitors connected electrically in series with a single switch. An IMG comprises a single stage or several stages distributed axially and connected in series. Each stage is powered by a single brick or several bricks distributed azimuthally within the stage and connected in parallel. The stages of a multistage IMG drive an impedance-matched coaxial transmission line with a conical center conductor. When the stages are triggered sequentially to launch a coherent traveling wave along the coaxial line, the IMG achieves electromagnetic-power amplification by triggered emission of radiation. Hence a multistage IMG is a pulsed-power analogue of a laser. To illustrate the IMG approach to prime power, we have developed conceptual designs of two ten-stage IMGs with LC time constants on the order of 100 ns. One design includes 20 bricks per stage, and delivers a peak electrical power of 1.05 TW to a matched-impedance 1.22-Ω load. The design generates 113 kV per stage and has a maximum energy efficiency of 89%. The other design includes a single brick per stage, delivers 68 GW to a matched-impedance 19-Ω load, generates 113 kV per stage, and has a maximum energy efficiency of 90%. For a given electrical-power-output time history, an IMG is less expensive and slightly more efficient than a linear transformer driver, since an IMG does not use ferromagnetic cores.

  9. Impedance-matched Marx generators

    Science.gov (United States)

    Stygar, W. A.; LeChien, K. R.; Mazarakis, M. G.; Savage, M. E.; Stoltzfus, B. S.; Austin, K. N.; Breden, E. W.; Cuneo, M. E.; Hutsel, B. T.; Lewis, S. A.; McKee, G. R.; Moore, J. K.; Mulville, T. D.; Muron, D. J.; Reisman, D. B.; Sceiford, M. E.; Wisher, M. L.

    2017-04-01

    We have conceived a new class of prime-power sources for pulsed-power accelerators: impedance-matched Marx generators (IMGs). The fundamental building block of an IMG is a brick, which consists of two capacitors connected electrically in series with a single switch. An IMG comprises a single stage or several stages distributed axially and connected in series. Each stage is powered by a single brick or several bricks distributed azimuthally within the stage and connected in parallel. The stages of a multistage IMG drive an impedance-matched coaxial transmission line with a conical center conductor. When the stages are triggered sequentially to launch a coherent traveling wave along the coaxial line, the IMG achieves electromagnetic-power amplification by triggered emission of radiation. Hence a multistage IMG is a pulsed-power analogue of a laser. To illustrate the IMG approach to prime power, we have developed conceptual designs of two ten-stage IMGs with L C time constants on the order of 100 ns. One design includes 20 bricks per stage, and delivers a peak electrical power of 1.05 TW to a matched-impedance 1.22 -Ω load. The design generates 113 kV per stage and has a maximum energy efficiency of 89%. The other design includes a single brick per stage, delivers 68 GW to a matched-impedance 19 -Ω load, generates 113 kV per stage, and has a maximum energy efficiency of 90%. For a given electrical-power-output time history, an IMG is less expensive and slightly more efficient than a linear transformer driver, since an IMG does not use ferromagnetic cores.

  10. Polymer microchip impedance spectroscopy through two parallel planar embedded microelectrodes: Understanding the impedance contribution of the surrounding polymer on the measurement accuracy

    International Nuclear Information System (INIS)

    Kechadi, Mohammed; Gamby, Jean; Chaal, Lila; Girault, Hubert; Saidani, Boualem; Tribollet, Bernard

    2013-01-01

    The present work describes a new methodology for contact free impedance of a solution in a polymer microchip taking into account the role played by the surrounding polymer on the impedance accuracy. Measurements were carried out using a photoablated polyethylene terephthalate (PET) microchannel above two embedded microband electrodes. The impedance diagrams exhibit a loop from high frequencies to medium frequencies (1 MHz–100 Hz) and a capacitive behavior at low frequencies (100–1 Hz). The impedance diagrams were corrected by eliminating from the global microchip response the contribution of the impedance of the PET layer between the two microband electrodes. This operation enables a clear observation of the impedance in the microchannel solution, including the bulk solution contribution and the interfacial capacitance related to the surface roughness of the photoablated microchannel. Models for the impedance of solutions of varying conductivity showed that the capacitance of the polymer–solution interface can be modeled by a constant phase element (CPE) with an exponent of 0.5. The loop diameter was found to be proportional to the microchannel resistivity, allowing a cell constant around 4.93 × 10 5 m −1 in contactless microelectrodes configuration

  11. Electrochemical impedance measurement of a carbon nanotube probe electrode

    International Nuclear Information System (INIS)

    Inaba, Akira; Takei, Yusuke; Kan, Tetsuo; Shimoyama, Isao; Matsumoto, Kiyoshi

    2012-01-01

    We measured and analyzed the electrochemical impedance of carbon nanotube (CNT) probe electrodes fabricated through the physical separation of insulated CNT bridges. The fabricated CNT electrodes were free-standing CNTs that were completely covered with an insulator, except for their tips. Typical dimensions of the nanoelectrodes were 1–10 nm in CNT diameter, 80–300 nm in insulator diameter, 0.5–4 μm in exposed CNT length and 1–10 μm in probe length. The electrochemical impedance at frequencies ranging from 40 Hz to 1 MHz was measured in physiological saline. The measured impedance of the CNT electrode was constant at 32 MΩ at frequencies below 1 kHz and was inversely proportional to frequency at frequencies above 10 kHz. By means of comparison with the parasitic capacitive impedance of the insulator membrane, we confirmed that the electrode was sufficiently insulated such that the measured constant impedance was given by the exposed CNT tip. Consequently, we can use the CNT electrode for highly localized electrochemical impedance measurements below 1 kHz. Considering an equivalent circuit and the nanoscopic dimensions of the CNT electrode, we demonstrated that the constant impedance was governed by diffusion impedance, whereas the solution resistance, charge-transfer resistance and double-layer capacitance were negligible. (paper)

  12. Unified Impedance Model of Grid-Connected Voltage-Source Converters

    DEFF Research Database (Denmark)

    Wang, Xiongfei; Harnefors, Lennart; Blaabjerg, Frede

    2018-01-01

    This paper proposes a unified impedance model of grid-connected voltage-source converters for analyzing dynamic influences of the Phase-Locked Loop (PLL) and current control. The mathematical relations between the impedance models in the different domains are first explicitly revealed by means...... of complex transfer functions and complex space vectors. A stationary (αβ-) frame impedance model is then proposed, which not only predicts the stability impact of the PLL, but reveals also its frequency coupling effect explicitly. Furthermore, the impedance shaping effect of the PLL on the current control...... results and theoretical analysis confirm the effectiveness of the stationary-frame impedance model....

  13. Superconducting active impedance converter

    International Nuclear Information System (INIS)

    Ginley, D.S.; Hietala, V.M.; Martens, J.S.

    1993-01-01

    A transimpedance amplifier for use with high temperature superconducting, other superconducting, and conventional semiconductors allows for appropriate signal amplification and impedance matching to processing electronics. The amplifier incorporates the superconducting flux flow transistor into a differential amplifier configuration which allows for operation over a wide temperature range, and is characterized by high gain, relatively low noise, and response times less than 200 picoseconds over at least a 10-80 K. temperature range. The invention is particularly useful when a signal derived from either far-IR focal plane detectors or from Josephson junctions is to be processed by higher signal/higher impedance electronics, such as conventional semiconductor technology. 12 figures

  14. Scene text detection by leveraging multi-channel information and local context

    Science.gov (United States)

    Wang, Runmin; Qian, Shengyou; Yang, Jianfeng; Gao, Changxin

    2018-03-01

    As an important information carrier, texts play significant roles in many applications. However, text detection in unconstrained scenes is a challenging problem due to cluttered backgrounds, various appearances, uneven illumination, etc.. In this paper, an approach based on multi-channel information and local context is proposed to detect texts in natural scenes. According to character candidate detection plays a vital role in text detection system, Maximally Stable Extremal Regions(MSERs) and Graph-cut based method are integrated to obtain the character candidates by leveraging the multi-channel image information. A cascaded false positive elimination mechanism are constructed from the perspective of the character and the text line respectively. Since the local context information is very valuable for us, these information is utilized to retrieve the missing characters for boosting the text detection performance. Experimental results on two benchmark datasets, i.e., the ICDAR 2011 dataset and the ICDAR 2013 dataset, demonstrate that the proposed method have achieved the state-of-the-art performance.

  15. Impedance pattern of vaginal and vestibular mucosa in cyclic goats

    Directory of Open Access Journals (Sweden)

    Ivo Křivánek

    2008-01-01

    Full Text Available The changes of vaginal and vestibular impedance during the oestrous cycle in goats were examined. The onset of oestrus was teased with a buck once a day during the experiment. Impedance was mea­sured by a four-terminal method. The vaginal impedance was recorded under slight pressure of electrodes to the vaginal dorsal wall at the cervix. The vestibular impedance was recorded under slight pressure of electrodes to the vestibular dorsal wall 5 cm from the vulva and at the vulva. The im­pe­dan­ce was measured once a day from 4 days before the expected oestrus to 6 days after onset of oestrus. The vaginal impedance at the cervix decreased during pro-oestrus (P < 0.01 and increased du­ring oestrus (P < 0.01. The vestibular impedance 5 cm from the vulva decreased during pro-oestrus (P < 0.01 and increased after oestrus (P < 0.01. The decrease of vaginal impedance during peri-oestrus was nearly twofold in comparison with the vestibular impedance 5 cm from the vulva. No sig­ni­fi­cant decrease of the vestibular impedance at the vulva was found during the oestrous cycle. The results indicate that the vaginal impedance at the cervix and vestibular impedance 5 cm from the vulva measured by means of a four-terminal method during the oestrous cycle display cyclic changes that are closely related to the oestrous behaviour of goats.

  16. Biphasic DC measurement approach for enhanced measurement stability and multi-channel sampling of self-sensing multi-functional structural materials doped with carbon-based additives

    Science.gov (United States)

    Downey, Austin; D'Alessandro, Antonella; Ubertini, Filippo; Laflamme, Simon; Geiger, Randall

    2017-06-01

    Investigation of multi-functional carbon-based self-sensing structural materials for structural health monitoring applications is a topic of growing interest. These materials are self-sensing in the sense that they can provide measurable electrical outputs corresponding to physical changes such as strain or induced damage. Nevertheless, the development of an appropriate measurement technique for such materials is yet to be achieved, as many results in the literature suggest that these materials exhibit a drift in their output when measured with direct current (DC) methods. In most of the cases, the electrical output is a resistance and the reported drift is an increase in resistance from the time the measurement starts due to material polarization. Alternating current methods seem more appropriate at eliminating the time drift. However, published results show they are not immune to drift. Moreover, the use of multiple impedance measurement devices (LCR meters) does not allow for the simultaneous multi-channel sampling of multi-sectioned self-sensing materials due to signal crosstalk. The capability to simultaneously monitor multiple sections of self-sensing structural materials is needed to deploy these multi-functional materials for structural health monitoring. Here, a biphasic DC measurement approach with a periodic measure/discharge cycle in the form of a square wave sensing current is used to provide consistent, stable resistance measurements for self-sensing structural materials. DC measurements are made during the measurement region of the square wave while material depolarization is obtained during the discharge region of the periodic signal. The proposed technique is experimentally shown to remove the signal drift in a carbon-based self-sensing cementitious material while providing simultaneous multi-channel measurements of a multi-sectioned self-sensing material. The application of the proposed electrical measurement technique appears promising for real

  17. Development of data acquisition and analysis software for multichannel detectors

    International Nuclear Information System (INIS)

    Chung, Y.

    1988-06-01

    This report describes the development of data acquisition and analysis software for Apple Macintosh computers, capable of controlling two multichannel detectors. With the help of outstanding graphics capabilities, easy-to-use user interface, and several other built-in convenience features, this application has enhanced the productivity and the efficiency of data analysis. 2 refs., 6 figs

  18. A high dutycycle low cost multichannel analyser for electron spectroscopy

    International Nuclear Information System (INIS)

    Norell, K.E.; Baltzer, P.

    1983-03-01

    A high dutycycle multichannel analyzer has been designed and used in time-of-flight electron spectroscopy. The memory capacity is 64k counts. The number of channels is 8192 with a time resolution of 100 ns. An oscilloscope is used to display the spectra synchronous with the counting. The unit has been built with standard electronic components. (author)

  19. A multichannel magnetic β-ray spectrometer for rapid measurements of electron spectra

    International Nuclear Information System (INIS)

    Kariya, Komyo; Morikawa, Kaoru.

    1989-01-01

    In order to make the magnetic β-ray spectrometer suitable for rapid measurements of electron spectra with short-lived nuclides, twelve small GM counters have been arrayed along the focal plane of a 180deg focusing flat type design. All the signal pulses from each one of these detectors are mixed together onto a single cable. By means of multichannel PHA, each pulse can be traced back to the specific detector which sent it out. In order to avoid time consuming evacuation procedures, the sample source is placed outside a thin window of the preevacuated analyzer chamber. By the use of this multichannel spectrometer a β-ray spectrum with maximum energy up to about 10 MeV can be measured within 1 min or so. Electron spectra measured with 113m In, 119m In and 144 Pr source are shown. (author)

  20. Transverse impedance of a periodic array of cavities

    Directory of Open Access Journals (Sweden)

    A. V. Fedotov

    1999-06-01

    Full Text Available We examine the transverse impedance of a periodic array of cavities in a beam pipe at high frequency. The calculation is an extension of a previous one for the longitudinal impedance of a periodic array of azimuthally symmetric pillboxes, for which only TM modes were needed. In the present case, we must include TE modes as well. In addition, we extend the applicability of the previous calculation by including an extra term in the coupling kernel so that the results are valid for all values of the ratio of the cavity length to the period of the structure (all values of the ratio of iris thickness to structure period. In spite of the presence of TE modes, we find that the high frequency limit of the transverse impedance is simply (2/ka^{2} times the corresponding limit of the longitudinal impedance, just as it is for the resistive wall impedances, a relation which occurs frequently for azimuthally symmetric structures. Finally, we present numerical results as well as approximate expressions for the impedance per period, valid for all ratios of cavity length to structure period.

  1. Development on electromagnetic impedance function modeling and its estimation

    Energy Technology Data Exchange (ETDEWEB)

    Sutarno, D., E-mail: Sutarno@fi.itb.ac.id [Earth Physics and Complex System Division Faculty of Mathematics and Natural Sciences Institut Teknologi Bandung (Indonesia)

    2015-09-30

    Today the Electromagnetic methods such as magnetotellurics (MT) and controlled sources audio MT (CSAMT) is used in a broad variety of applications. Its usefulness in poor seismic areas and its negligible environmental impact are integral parts of effective exploration at minimum cost. As exploration was forced into more difficult areas, the importance of MT and CSAMT, in conjunction with other techniques, has tended to grow continuously. However, there are obviously important and difficult problems remaining to be solved concerning our ability to collect process and interpret MT as well as CSAMT in complex 3D structural environments. This talk aim at reviewing and discussing the recent development on MT as well as CSAMT impedance functions modeling, and also some improvements on estimation procedures for the corresponding impedance functions. In MT impedance modeling, research efforts focus on developing numerical method for computing the impedance functions of three dimensionally (3-D) earth resistivity models. On that reason, 3-D finite elements numerical modeling for the impedances is developed based on edge element method. Whereas, in the CSAMT case, the efforts were focused to accomplish the non-plane wave problem in the corresponding impedance functions. Concerning estimation of MT and CSAMT impedance functions, researches were focused on improving quality of the estimates. On that objective, non-linear regression approach based on the robust M-estimators and the Hilbert transform operating on the causal transfer functions, were used to dealing with outliers (abnormal data) which are frequently superimposed on a normal ambient MT as well as CSAMT noise fields. As validated, the proposed MT impedance modeling method gives acceptable results for standard three dimensional resistivity models. Whilst, the full solution based modeling that accommodate the non-plane wave effect for CSAMT impedances is applied for all measurement zones, including near-, transition

  2. Development of a Multichannel Analyzer for modular ADCs

    International Nuclear Information System (INIS)

    Bannos Rodriguez, U.; Diaz Castro, M.; Rivero Ramirez, D.

    2013-01-01

    This paper describes the design and construction of a multichannel analyzer with USB interface from ADC module of the Fast ComTec 7074. One PIC18F4550 microprocessor from Microchip, one CPLD isPLSI 1032E from Lattice and one 32Kx8 SRAM memory were used. It also includes details of the programming circuitry and development of program acquisition, storage and display of the spectra using the Qt libraries. Finally, preliminary tests to the device are show. (Author)

  3. Mimicking multi-channel scattering with single-channel approaches

    OpenAIRE

    Grishkevich, Sergey; Schneider, Philipp-Immanuel; Vanne, Yulian V.; Saenz, Alejandro

    2009-01-01

    The collision of two atoms is an intrinsic multi-channel (MC) problem as becomes especially obvious in the presence of Feshbach resonances. Due to its complexity, however, single-channel (SC) approximations, which reproduce the long-range behavior of the open channel, are often applied in calculations. In this work the complete MC problem is solved numerically for the magnetic Feshbach resonances (MFRs) in collisions between generic ultracold 6Li and 87Rb atoms in the ground state and in the ...

  4. Astronomical observations with the optical multichannel analyser of the Sao Paulo University

    Energy Technology Data Exchange (ETDEWEB)

    Codina-Landaberry, S J; de Freitas Pacheco, J A [Universidade Mackenzie, Sao Paulo (Brazil). Centro de Radio-Astronomia e Astrofisica

    1979-03-01

    The first astronomical observations made with the optical multichannel analyser (OMA) of the Sao Paulo University is reported. A detailed description of the instrumentation is given as well as the results derived from the observation of some emission nebulae.

  5. The Role of Multichannel Marketing in Customer Retention and Loyalty: Study in Emerald Bank Customer in Indonesia

    OpenAIRE

    Ambarwati Ambarwati; Djumilah Zain Hadiwidjojo; Achmad Sudiro; Fatchur Rohman

    2015-01-01

    Attention on the relationship between customer retention, customer loyalty, and customer satisfaction that serves as "seed" of customer loyalty highlight the important factors for multichannel management. With the growing trends of people in investing their money in bank for securities need to be responded by the marketing department to create better marketing strategies. The purpose of this study is to examine and explain the effect of a multichannel bank on emerald customers retention   in ...

  6. Wearable impedance monitoring system for dialysis patients.

    Science.gov (United States)

    Bonnet, S; Bourgerette, A; Gharbi, S; Rubeck, C; Arkouche, W; Massot, B; McAdams, E; Montalibet, A; Jallon, P

    2016-08-01

    This paper describes the development and the validation of a prototype wearable miniaturized impedance monitoring system for remote monitoring in home-based dialysis patients. This device is intended to assess the hydration status of dialysis patients using calf impedance measurements. The system is based on the low-power AD8302 component. The impedance calibration procedure is described together with the Cole parameter estimation and the hydric volume estimation. Results are given on a test cell to validate the design and on preliminary calf measurements showing Cole parameter variations during hemodialysis.

  7. A New Multichannel Spectral Imaging Laser Scanning Confocal Microscope

    Directory of Open Access Journals (Sweden)

    Yunhai Zhang

    2013-01-01

    Full Text Available We have developed a new multichannel spectral imaging laser scanning confocal microscope for effective detection of multiple fluorescent labeling in the research of biological tissues. In this paper, the design and key technologies of the system are introduced. Representative results on confocal imaging, 3-dimensional sectioning imaging, and spectral imaging are demonstrated. The results indicated that the system is applicable to multiple fluorescent labeling in biological experiments.

  8. Multichannel Baseband Processor for Wideband CDMA

    Directory of Open Access Journals (Sweden)

    Jim Lin

    2005-07-01

    Full Text Available The system architecture of the cellular base station modem engine (CBME is described. The CBME is a single-chip multichannel transceiver capable of processing and demodulating signals from multiple users simultaneously. It is optimized to process different classes of code-division multiple-access (CDMA signals. The paper will show that through key functional system partitioning, tightly coupled small digital signal processing cores, and time-sliced reuse architecture, CBME is able to achieve a high degree of algorithmic flexibility while maintaining efficiency. The paper will also highlight the implementation and verification aspects of the CBME chip design. In this paper, wideband CDMA is used as an example to demonstrate the architecture concept.

  9. Multichannel Seismic Reflection - SCAR- Antarctic Penn. 1987-88 SDLS CD-ROM vol 27

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data recorded during 1987-88 in the Antarctica Peninsula region, by Petrobras, Brazil. The following...

  10. Multichannel Seismic Reflection - SCAR- Antarctic Penn. 1987-88 SDLS CD-ROM vol 26

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data recorded during 1987-88 in the Antarctica Peninsula region, by Petrobras, Brazil. The following...

  11. Study on electrical impedance matching for broadband ultrasonic transducer

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Geon Woo [University of Science and Technology, Daejeon (Korea, Republic of); Kim, Ki Bok [Korea Research Institute of Standards and Science, Center for Safety Measurement, Daejeon (Korea, Republic of); Baek, Kwang Sae [Elache Co., Busan (Korea, Republic of)

    2017-02-15

    Ultrasonic transducers with high resolution and resonant frequency are required to detect small defects (less than hundreds of μm) by ultrasonic testing. The resonance frequency and resolution of an ultrasonic transducer are closely related to the thickness of piezo-electric materials, backing materials, and the electric impedance matching technique. Among these factors, electrical impedance matching plays an important role because it can reduce the loss and reflection of ultrasonic energy differences in electrical impedance between an ultrasonic transducer and an ultrasonic defects detecting system. An LC matching circuit is the most frequently used electric matching method. It is necessary for the electrical impedance of an ultrasonic transducer to correspond to approximately 50 Ω to compensate the difference in electrical impedance between both connections. In this study, a 15 MHz immersion ultrasonic transducer was fabricated and an LC electrical impedance circuit was applied to that for having broad-band frequency characteristic.

  12. Personalized multi-channel headphone sound reproduction based on active noise cancellation

    NARCIS (Netherlands)

    Schobben, D.W.E.; Aarts, R.M.

    2005-01-01

    A system for headphone signal processing is discussed which gives a listener the same impression as listening to a multi-channel loudspeaker set-up. It is important that this processing is optimized for each individual listener. If this is not the case, large localization errors may occur. In the

  13. Autonomous transmission power adaptation for multi-radio multi-channel wireless mesh networks

    CSIR Research Space (South Africa)

    Olwal, TO

    2009-09-01

    Full Text Available Multi-Radio Multi-Channel (MRMC) systems are key to power control problems in WMNs. Previous studies have emphasized through- put maximization in such systems as the main design challenge and transmission power control treated as a secondary issue...

  14. Autonomous transmission power adaptation for multi-radio multi-channel wireless mesh networks

    CSIR Research Space (South Africa)

    Olwal, TO

    2008-09-01

    Full Text Available Multi-Radio Multi-Channel (MRMC) systems are key to power control problems in WMNs. Previous studies have emphasized throughput maximization in such systems as the main design challenge and transmission power control treated as a secondary issue...

  15. Astronomical observations with the optical multichannel analyser of the Sao Paulo University

    International Nuclear Information System (INIS)

    Codina-Landaberry, S.J.; Freitas Pacheco, J.A. de

    1979-01-01

    The first astronomical observations made with the optical multichannel analyser (OMA) of the Sao Paulo University is reported. A detailed description of the instrumentation is given as well as the results derived from the observation of some emission nebulae [pt

  16. A high-throughput, multi-channel photon-counting detector with picosecond timing

    Science.gov (United States)

    Lapington, J. S.; Fraser, G. W.; Miller, G. M.; Ashton, T. J. R.; Jarron, P.; Despeisse, M.; Powolny, F.; Howorth, J.; Milnes, J.

    2009-06-01

    High-throughput photon counting with high time resolution is a niche application area where vacuum tubes can still outperform solid-state devices. Applications in the life sciences utilizing time-resolved spectroscopies, particularly in the growing field of proteomics, will benefit greatly from performance enhancements in event timing and detector throughput. The HiContent project is a collaboration between the University of Leicester Space Research Centre, the Microelectronics Group at CERN, Photek Ltd., and end-users at the Gray Cancer Institute and the University of Manchester. The goal is to develop a detector system specifically designed for optical proteomics, capable of high content (multi-parametric) analysis at high throughput. The HiContent detector system is being developed to exploit this niche market. It combines multi-channel, high time resolution photon counting in a single miniaturized detector system with integrated electronics. The combination of enabling technologies; small pore microchannel plate devices with very high time resolution, and high-speed multi-channel ASIC electronics developed for the LHC at CERN, provides the necessary building blocks for a high-throughput detector system with up to 1024 parallel counting channels and 20 ps time resolution. We describe the detector and electronic design, discuss the current status of the HiContent project and present the results from a 64-channel prototype system. In the absence of an operational detector, we present measurements of the electronics performance using a pulse generator to simulate detector events. Event timing results from the NINO high-speed front-end ASIC captured using a fast digital oscilloscope are compared with data taken with the proposed electronic configuration which uses the multi-channel HPTDC timing ASIC.

  17. A high-throughput, multi-channel photon-counting detector with picosecond timing

    International Nuclear Information System (INIS)

    Lapington, J.S.; Fraser, G.W.; Miller, G.M.; Ashton, T.J.R.; Jarron, P.; Despeisse, M.; Powolny, F.; Howorth, J.; Milnes, J.

    2009-01-01

    High-throughput photon counting with high time resolution is a niche application area where vacuum tubes can still outperform solid-state devices. Applications in the life sciences utilizing time-resolved spectroscopies, particularly in the growing field of proteomics, will benefit greatly from performance enhancements in event timing and detector throughput. The HiContent project is a collaboration between the University of Leicester Space Research Centre, the Microelectronics Group at CERN, Photek Ltd., and end-users at the Gray Cancer Institute and the University of Manchester. The goal is to develop a detector system specifically designed for optical proteomics, capable of high content (multi-parametric) analysis at high throughput. The HiContent detector system is being developed to exploit this niche market. It combines multi-channel, high time resolution photon counting in a single miniaturized detector system with integrated electronics. The combination of enabling technologies; small pore microchannel plate devices with very high time resolution, and high-speed multi-channel ASIC electronics developed for the LHC at CERN, provides the necessary building blocks for a high-throughput detector system with up to 1024 parallel counting channels and 20 ps time resolution. We describe the detector and electronic design, discuss the current status of the HiContent project and present the results from a 64-channel prototype system. In the absence of an operational detector, we present measurements of the electronics performance using a pulse generator to simulate detector events. Event timing results from the NINO high-speed front-end ASIC captured using a fast digital oscilloscope are compared with data taken with the proposed electronic configuration which uses the multi-channel HPTDC timing ASIC.

  18. Concentration Impedance in Testing of Solid Oxide Cells Revisited

    DEFF Research Database (Denmark)

    Mogensen, Mogens Bjerg; Ebbesen, Sune Dalgaard; Jensen, Søren Højgaard

    2017-01-01

    The concentration impedance originating from diffusion and reactant conversion impedance of the Ni-YSZ supported fuel electrode in solid oxide cell has been treated many times during the latest couple of decades. In spite of this, the separation of the diffusion impedance from the conversion...

  19. Compact and cost-effective multi-channel optical spectrometer for fine FBG sensing in IoT technology

    Science.gov (United States)

    Konishi, Tsuyoshi; Yamasaki, Yu

    2018-02-01

    Optical fiber sensor networks have attracted much attention in IoT technology and a fiber Bragg grating is one of key sensor devices there because of their advantages in a high affinity for optical fiber networks, compactness, immunity to electromagnetic interference and so on. Nevertheless, its sensitivity is not always satisfactory so as to be usable together with widespread cost-effective multi-channel spectrometers. In this paper, we introduce a new cost-effective approach for a portable multi-channel spectrometer with high spectral resolution and demonstrates some preliminary experimental results for fine FBG sensing.

  20. Spatial aspects of sound quality - and by multichannel systems subjective assessment of sound reproduced by stereo

    DEFF Research Database (Denmark)

    Choisel, Sylvain

    the fidelity with which sound reproduction systems can re-create the desired stereo image, a laser pointing technique was developed to accurately collect subjects' responses in a localization task. This method is subsequently applied in an investigation of the effects of loudspeaker directivity...... on the perceived direction of panned sources. The second part of the thesis addresses the identification of auditory attributes which play a role in the perception of sound reproduced by multichannel systems. Short musical excerpts were presented in mono, stereo and several multichannel formats to evoke various...

  1. Development and implementation of own software for dosimetry multichannel film; Desarrollo e implementacion de un software propio para la dosimetria multicanal con pelicula radiocromica EBT2

    Energy Technology Data Exchange (ETDEWEB)

    Jimenez Feltstrom, D.; Reyes Garcia, R.; Luis Simon, F. J.; Carrasco Herrera, M.; Sanchez Carmona, G.; Herrador Cordoba, M.

    2013-07-01

    The objective of this work is to develop its own software for multichannel film dosimetry Radiochromic EBT2. Compare the results obtained with its use in multichannel and single-channel dosimetry. Check that the multi-channel dosimetry eliminates much of the artifacts caused by dirt, fingerprints, scratches, etc. Radiochromic in film and scanner devices. (Author)

  2. Multichannel Seismic Reflection Data - SCAR - Ross Sea - 1987, SDLS CD-ROM vol 13

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data recorded during the 1987 field season in the Ross Sea, Antarctica, by SEVMORGEOLOGIA, RUSSIA. The...

  3. Multichannel Seismic Reflection Data - SCAR - Ross Sea - 1980, SDLS CD-ROM vol 3

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data from four lines recorded during 1980 in the Ross Sea, Antarctica, by the Bundesanstalt fur...

  4. Multichannel Seismic Reflection Data - SCAR - Ross Sea - 1980, SDLS, CD-ROM vol 4

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data from seven lines recorded during 1980 in the Ross Sea, Antarctica, by the Bundesanstalt fur...

  5. Multichannel Seismic Reflection Data - SCAR - Ross Sea - 1989, SDLS CD-ROM vol 14

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data recorded during 1989 field season in the Ross Sea, Antarctica, by the SEVMORGEOLOGIA, RUSSIS. The...

  6. Multichannel Seismic Reflection Data - SCAR - Ross Sea 1980, SDLS, CD-ROM vol 5

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data from eleven lines recorded during 1980 in the Ross Sea, Antarctica, by the Bundesanstalt fur...

  7. Multichannel Seismic Reflection Data - SCAR - Wilkes Land, 1983, SDLS CD-ROM vol 10

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data from thirteen lines recorded during 1983 off Wilkes Island, Antarctica, by the Japan National Oil...

  8. Multichannel Seismic Reflection Data - SCAR - Wilkes Land 1982, SDLS CD-ROM vol 11

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data from sixteen lines recorded during 1982 off Wilkes Island, Antarctica, by the Institut Francais du...

  9. Association of the route of blood flow channel through an intraluminal thrombus with the abdominal aortic aneurysm rupture in imaging diagnostics

    International Nuclear Information System (INIS)

    Wiernicki, I.; Gutowski, P.; Kownacki, L.; Polanowski, L.; Gorecka-Szyld, B.; Cyrylowski, L.

    2004-01-01

    The location of the abdominal aortic aneurysm (AAA) rupture probably influences the patient's morbidity and mortality. No reliable predictors for time and site of the rupture have been found to date. An opinion that intraluminal, parietal thrombus (PT) may play a protective role against the rupture predominates in recent reports. The aim of our study was to evaluate a route of blood flow channel (BFC) through intraluminal PT in AAA. In this prospective study, the thrombus morphology was evaluated in 103 patients with AAA, divided into three groups according to the aneurysm size: group 1 - patients with AAA 30 - 39 mm in maximal diameter, group 2: 40 - 49 mm, and group 3: more than 49 mm. All AAAs were examined with Doppler ultrasound, computed tomography, and magnetic resonance imaging. Anterior, medial, and posterior BFC was defined on the basis of calculated ratio of anterior wall PT thickness to posterior wall PT thickness. Anterior BFC predominates in AAA in group 1 - 39%, while its frequency in group 3 was 21%. Posterior BFC was significantly more frequent in group 3 - 67% than in group 1 - 24%. Both differences were statistically significant (p = 0.03). PT thickness increases in direct proportion to the size of AAA, and with this increase BFC in the thrombus most frequently shifts backward. A lack of PT or its trace may indicate a site of potential rupture of the weakened wall. Patients with AAA and a parietal route of BFC in the thrombus are of higher risk of rupture despite small aneurysm size. In qualification for surgery, the morphology of the thrombus should be considered, in addition to the maximal diameter of AAA. (author)

  10. Assessment of chest impedance in relation to phonocardiography

    DEFF Research Database (Denmark)

    Zimmermann, Niels Henrik; Møller, Henrik; Hammershøi, Dorte

    2010-01-01

    the surface of the skin to the transducer. If the impedance of the skin is known, it may be possible to optimize the transducer to achieve an improved signal for a certain frequency range, while attenuating disturbing noise. Further, from a classical stethoscope it is known, that the sound picked up...... by the stethoscope can be influenced by changing the pressure on the chest piece of the stethoscope. A high pressure will stretch the skin similar to a drum skin, and attenuate lower frequencies, while lighter pressure will broaden the frequency range. By using an impedance tube (also known as standing wave tube......), it is possible to measure the impedance of the surface of the skin and at the same time investigate the influence of different pressures and diameters of a transducer. The impedance tube is made specifically with the purpose of measuring chest impedances in the frequency range from 50 Hz to 5 kHz. An MLS...

  11. Possibilities of electrical impedance tomography in gynecology

    International Nuclear Information System (INIS)

    Trokhanova O V; Chijova Y A; Okhapkin M B; Korjenevsky A V; Tuykin T S

    2013-01-01

    The paper describes results of comprehensive EIT diagnostics of mammary glands and cervix. The data were obtained from examinations of 170 patients by EIT system MEM (multi-frequency electrical impedance mammograph) and EIT system GIT (gynecological impedance tomograph). Mutual dependence is discussed.

  12. Entrance and Exit CSR Impedance for Non-Ultrarelativistic Beam

    Energy Technology Data Exchange (ETDEWEB)

    Li, Rui; Tsai, Cheng Ying [SLAC National Accelerator Lab., Menlo Park, CA (United States); Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States)

    2017-05-01

    For a high-brightness electron beam being transported through beamlines involving bending systems, the coherent synchrotron radiation (CSR) and longitudinal space charge (LSC) interaction could often cause microbunching instability. The semi-analytical Vlasov solver for microbunching gain* depends on the impedances for the relevant collective effects. The existing results for CSR impedances are usually obtained for the ultrarelativistic limit. To extend the microbunching analysis to cases of low energies, such as the case of an ERL merger, or to density modulations at extremely small wavelength, it is necessary to extend the impedance analysis to the non-ultrarelativistic regime. In this study, we present the impedance analysis for the transient CSR interaction in the non-ultrarelativistic regime, for transients including both entrance to and exit from a magnetic dipole. These impedance results will be compared to their ultra-relativistic counterparts**, and the corresponding wakefield obtained from the impedance for low-energy beams will be compared with the existing results of transient CSR wakefield for general beam energies***.

  13. Microelectrical Impedance Spectroscopy for the Differentiation between Normal and Cancerous Human Urothelial Cell Lines: Real-Time Electrical Impedance Measurement at an Optimal Frequency

    Directory of Open Access Journals (Sweden)

    Yangkyu Park

    2016-01-01

    Full Text Available Purpose. To distinguish between normal (SV-HUC-1 and cancerous (TCCSUP human urothelial cell lines using microelectrical impedance spectroscopy (μEIS. Materials and Methods. Two types of μEIS devices were designed and used in combination to measure the impedance of SV-HUC-1 and TCCSUP cells flowing through the channels of the devices. The first device (μEIS-OF was designed to determine the optimal frequency at which the impedance of two cell lines is most distinguishable. The μEIS-OF trapped the flowing cells and measured their impedance at a frequency ranging from 5 kHz to 1 MHz. The second device (μEIS-RT was designed for real-time impedance measurement of the cells at the optimal frequency. The impedance was measured instantaneously as the cells passed the sensing electrodes of μEIS-RT. Results. The optimal frequency, which maximized the average difference of the amplitude and phase angle between the two cell lines (p<0.001, was determined to be 119 kHz. The real-time impedance of the cell lines was measured at 119 kHz; the two cell lines differed significantly in terms of amplitude and phase angle (p<0.001. Conclusion. The μEIS-RT can discriminate SV-HUC-1 and TCCSUP cells by measuring the impedance at the optimal frequency determined by the μEIS-OF.

  14. Impedance analysis on organic ultrathin layers

    Energy Technology Data Exchange (ETDEWEB)

    Bom, Sidhant; Wagner, Veit [Jacobs University Bremen, School of Engineering and Science, Campus Ring 8, 28759 Bremen (Germany)

    2008-07-01

    Impedance spectroscopy is a standard technique for thin film analysis to obtain important information as thicknesses, diffusion properties of mobile ions and leakage currents. The measured electrical impedance of a sample is modeled by a physical equivalent circuit of resistors and capacitors. In the present work this information is obtained as a function of frequency also for ultrathin organic layers in the monolayer regime. A series of semiconducting and insulating polymers (regioregular poly-3-hexylthiophene (rr-P3HT), polymethylmethacrylate (PMMA)) and self assembled monolayers (octadecyltrichlorosilane (OTS), hexamethyldisilazane (HMDS), thiolated phospholipids) were deposited either on highly n-doped silicon wafers or on gold surfaces. E.g. ultrathin layers were obtained by dip coating a silicon wafer in rr-P3HT solution in chloroform. The thickness of 2 nm determined for this system by impedance measurement agrees well with the atomic force microscopy analysis and corresponds to a single layer of polymer chains. The leakage current is seen as an ohmic contribution at low frequencies and allows a systematic optimization of process parameters. In summary, impedance spectroscopy allows very fast and convenient analysis of thin organic layers even down to the monolayer regime.

  15. Multichannel Seismic Reflection Data - SCAR - Weddell Sea - 1978, SDLS CD-ROM vol 19

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data recorded during 1978 in the Weddell Sea and Queen Maud Land, Antarctica, by the Bundesanstalt fur...

  16. Multichannel Seismic Reflection Data - SCAR, Ross Sea - 1982-1983, CD-ROM vol 9

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data from fourteen lines recorded during 1982 in the Ross Sea and Wilkes Island, Antarctica, by the...

  17. Multichannel Seismic Reflection Data - SCAR - Weddell Sea - 1978, SDLS CD-ROM vol 18

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data recorded during 1978 in the Weddell Sea and Queen Maud Land, Antarctica, by the Bundesanstalt fur...

  18. Multichannel Seismic Reflection Data - SCAR - Weddell Sea - 1978, SDLS CD-ROM vol 17

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data recorded during 1978 in the Weddell Sea and Queen Maud Land, Antarctica, by the Bundesanstalt fur...

  19. Multichannel Seismic Reflection Data - SCAR - Antarctic Peninsula - 1985, SDLS CD-ROM vol 16

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data recorded during 1985 field season along the north side of the Antarctic-Peninsula by the British...

  20. Multichannel Seismic Reflection Data - SCAR - Ross Sea 1982, SDLS CD-ROM vol 12

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are stacked multichannel marine seismic reflection data from seven lines recorded during 1982 in the Ross Sea, Antarctica, by the Institut Francais du...

  1. A new implementation of multichannel radiochromic film dosimetry; Una nueva implementacion del analisis multicanal para la dosimetria mediante peliculas radiocromicas

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez Rodriguez, C.; Martin Martin, G.; Bermudez Luna, R.; Lopez Fernandez, A.; Tores Olombrada, M. V. de

    2014-07-01

    The aims of this paper are to carry out a new implementation of the multichannel radiochromic film dosimetry (Micke A, Lewis D, Yu X. Multichannel film dosimetry with nonuniformity correction. Med Phys 2011;38:2523-34), to quantify the variation in gamma index as compared to the single channel film dosimetry, and to determine if the procedure achieves similar results by means of a different scanner that the one used by Micke et al. Radiochromic EBT2 films and a Microtek 9000 XL scanner were used. Our procedure simplifies the system calibration splitting it into two factors, manufactured batch and digitalization specific. Absorbed dose spatial distributions from an open radiotherapy beam without any modulation and 20 IMRT treatments were determined. Their gamma index maps were calculated and a comparison of the results from single channel and multichannel dosimetry was performed. A 5% mean increase in concordance was obtained by using the multichannel film dosimetry. Our results are similar to those reported by Micke et al. even though we are using a different scanner. (Author)

  2. Impacts of endoscopic gastroesophageal flap valve grading on pediatric gastroesophageal reflux disease.

    Directory of Open Access Journals (Sweden)

    Kai-Chi Chang

    Full Text Available Gastroesophageal flap valve (GEFV endoscopic grading is reported to be associated with gastroesophageal reflux disease (GERD in adults; however its role in pediatric groups remains unknown. This study aimed to investigate the significance of GEFV grading and the associations to multichannel intraluminal impedance and pH monitoring (MII-pH in children with GERD.A total of 48 children with GERD symptoms who received esophagogastroduodenoscopy and MII-pH monitoring were enrolled. The degree of GEFV was graded from I to IV according to the Hill classification, and classified into two groups: normal GEFV (Hill grades I and II, and abnormal GEFV (Hill grades III and VI. Endoscopic findings and MII-pH monitoring were analyzed among the groups.Thirty-six patients had normal GEFV while 12 had abnormal GEFV. The presence of erosive esophagitis was significantly more common in the patients with abnormal GEFV (p = 0.037, OR 9.84, 95% CI 1.15-84.42. Pathological acidic gastroesophageal reflux (GER determined by MII-pH was more prevalent in the patients with loosened GEFV geometry (p = 0.01, OR 7.0, 95% CI 1.67-27.38. There were significant positive correlations between GEFV Hill grading I to IV and the severity of erosive esophagitis (r = 0.49, p<0.001, percentage of supine acid reflux (r = 0.37, p = 0.009, percentage of total acid reflux (r = 0.3284, p = 0.023, and DeMeester score (r = 0.36, p = 0.01 detected by pH monitoring. In the impedance study, GEFV Hill grading also positively correlated to median number of acid reflux events (r = 0.3015, p = 0.037.GEFV dysfunction highly associated with acid GER and severe erosive esophagitis. An abnormal GEFV is a sign of acid GER in children.

  3. The Single- and Multichannel Audio Recordings Database (SMARD)

    DEFF Research Database (Denmark)

    Nielsen, Jesper Kjær; Jensen, Jesper Rindom; Jensen, Søren Holdt

    2014-01-01

    A new single- and multichannel audio recordings database (SMARD) is presented in this paper. The database contains recordings from a box-shaped listening room for various loudspeaker and array types. The recordings were made for 48 different configurations of three different loudspeakers and four...... different microphone arrays. In each configuration, 20 different audio segments were played and recorded ranging from simple artificial sounds to polyphonic music. SMARD can be used for testing algorithms developed for numerous application, and we give examples of source localisation results....

  4. Quantification of coating aging using impedance measurements

    NARCIS (Netherlands)

    Westing, E.P.M. van; Weijde, D.H. van der; Vreijling, M.P.W.; Ferrari, G.M.; Wit, J.H.W. de

    1998-01-01

    This chapter shows the application results of a novel approach to quantify the ageing of organic coatings using impedance measurements. The ageing quantification is based on the typical impedance behaviour of barrier coatings in immersion. This immersion behaviour is used to determine the limiting

  5. Mechanical impedance of the human body in vertical direction.

    Science.gov (United States)

    Holmlund, P; Lundström, R; Lindberg, L

    2000-08-01

    The mechanical impedance of the human body in sitting posture and vertical direction was measured during different experimental conditions, such as vibration level (0.5-1.4 m/s2), frequency (2-100 Hz), body weight (57-92 kg), relaxed and erect upper body posture. The outcome shows that impedance increases with frequency up to a peak at about 5 Hz after which it decreases in a complex manner which includes two additional peaks. The frequency at which the first and second impedance peak occurs decreases with higher vibration level. Erect, compared with relaxed body posture resulted in higher impedance magnitudes and with peaks located at somewhat higher frequencies. Heavy persons show higher impedance magnitudes and peaks at lower frequencies.

  6. Electrical Impedance Measurements of PZT Nanofiber Sensors

    Directory of Open Access Journals (Sweden)

    Richard Galos

    2017-01-01

    Full Text Available Electrical impedance measurements of PZT nanofiber sensors were performed using a variety of methods over a frequency spectrum ranging from DC to 1.8 GHz. The nanofibers formed by electrospinning with diameters ranging from 10 to 150 nm were collected and integrated into sensors using microfabrication techniques. Special matching circuits with ultrahigh input impedance were fabricated to produce low noise, measurable sensor outputs. Material properties including resistivity and dielectric constant are derived from the impedance measurements. The resulting material properties are also compared with those of individual nanofibers being tested using conductive AFM and Scanning Conductive Microscopy.

  7. Laboratory scale tests of electrical impedence tomography

    International Nuclear Information System (INIS)

    Binley, A; Daily, W; LaBredcque, D; Ramirez, A.

    1998-01-01

    Electrical impedance tomographs (magnitude and phase) of known, laboratory-scale targets are reported. Three methods are used to invert electrical impedance data and their tomographs compared. The first method uses an electrical resistance tomography (ERT) algonthm (designed for DC resistivity inversion) to perform impedance magnitude inversion and a linearized perturbation approach (PA) to invert the imaginary part. The second approximate method compares ERT magnitude inversions at two frequencies and uses the frequency effect (FE) to compute phase tomographs. The third approach, electrrcal impedance tomography (EIT), employs fully complex algebra to account for the real and imaginary components of electrical impedance data. The EIT approach provided useful magnitude and phase images for the frequency range of 0.0625 to 64 Hz; images for higher frequencies were not reliable. Comparisons of the ERT and EIT magnitude images show that both methods provided equivalent results for the water blank, copper rod and PVC rod targets. The EIT magnitude images showed better spatial resolutron for a sand-lead mixture target. Phase images located anomalies of both high and low contrast IP and provided better spatial resolution than the magnitude images. When IP was absent from the data, the EIT algorithm reconstructed phase values consistent with the data noise levels

  8. PREFACE: XV International Conference on Electrical Bio-Impedance (ICEBI) & XIV Conference on Electrical Impedance Tomography (EIT)

    Science.gov (United States)

    Pliquett, Uwe

    2013-04-01

    Over recent years advanced measurement methods have facilitated outstanding achievements not only in medical instrumentation but also in biotechnology. Impedance measurement is a simple and innocuous way to characterize materials. For more than 40 years biological materials, most of them based on cells, have been characterized by means of electrical impedance for quality control of agricultural products, monitoring of biotechnological or food processes or in health care. Although the list of possible applications is long, very few applications successfully entered the market before the turn of the century. This was, on the one hand, due to the low specificity of electrical impedance with respect to other material properties because it is influenced by multiple factors. On the other hand, equipment and methods for many potential applications were not available. With the appearance of microcontrollers that could be easily integrated in applications at the beginning of the 1980s, impedance measurement advanced as a valuable tool in process optimization and lab automation. However, established methods and data processing were mostly used in a new environment. This has changed significantly during the last 10 years with a dramatic growth of the market for medical instrumentation and also for biotechnological applications. Today, advanced process monitoring and control require fast and highly parallel electrical characterization which in turn yields incredible data volumes that must be handled in real time. Many newer developments require miniaturized but precise sensing methods which is one of the main parts of Lab-on-Chip technology. Moreover, biosensors increasingly use impedometric transducers, which are not compatible with the large expensive measurement devices that are common in the laboratory environment. Following the achievements in the field of bioimpedance measurement, we will now witness a dramatic development of new electrode structures and electronics

  9. Development of impedance matching technologies for ICRF antenna arrays

    International Nuclear Information System (INIS)

    Pinsker, R.I.

    1998-01-01

    All high-power ion cyclotron range of frequency (ICRF) heating systems include devices for matching the input impedance of the antenna array to the generator output impedance. For most types of antennas used, the input impedance is strongly time dependent on timescales as rapid as 10 -1 s, while the radio frequency (RF) generators used are capable of producing full power only into a stationary load impedance. Hence, the dynamic response of the matching method is of great practical importance. In this paper, world-wide developments in this field over the past decade are reviewed. These techniques may be divided into several classes. The edge plasma parameters that determine the antenna array's input impedance may be controlled to maintain a fixed load impedance. The frequency of the RF source can be feedback controlled to compensate for changes in the edge plasma conditions, or fast variable tuning elements in the transmission line between the generator output and the antenna input connections can provide the necessary time-varying impedance transformation. In 'lossy passive schemes', reflected power due to the time-varying impedance of the antenna array is diverted to a dummy load. Each of these techniques can be applied to a pre-existing antenna system. If a new antenna is to be designed, recent advances allow the antenna array to have the intrinsic property of presenting a constant load to the feeding transmission lines despite the varying load seen by each antenna in the array. (author)

  10. Development of impedance matching technologies for ICRF antenna arrays

    International Nuclear Information System (INIS)

    Pinsker, R.I.

    1998-03-01

    All high power ICRF heating systems include devices for matching the input impedance of the antenna array to the generator output impedance. For most types of antennas used, the input impedance is strongly time-dependent on timescales as rapid as 10-4 s, while the rf generators used are capable of producing full power only into a stationary load impedance. Hence, the dynamic response of the matching method is of great practical importance. In this paper, world-wide developments in this field over the past decade are reviewed. These techniques may be divided into several classes. The edge plasma parameters that determine the antenna array's input impedance may be controlled to maintain a fixed load impedance. The frequency of the rf source can be feedback controlled to compensate for changes in the edge plasma conditions, or fast variable tuning elements in the transmission line between the generator output and the antenna input connections can provide the necessary time-varying impedance transformation. In lossy passive schemes, reflected power due to the time-varying impedance of the antenna array is diverted to a dummy load. Each of these techniques can be applied to a pre-existing antenna system. If a new antenna is to be designed, recent advances allow the antenna array to have the intrinsic property of presenting a constant load to the feeding transmission lines despite the varying load seen by each antenna in the array

  11. Real-Time Thevenin Impedance Computation

    DEFF Research Database (Denmark)

    Sommer, Stefan Horst; Jóhannsson, Hjörtur

    2013-01-01

    operating state, and strict time constraints are difficult to adhere to as the complexity of the grid increases. Several suggested approaches for real-time stability assessment require Thevenin impedances to be determined for the observed system conditions. By combining matrix factorization, graph reduction......, and parallelization, we develop an algorithm for computing Thevenin impedances an order of magnitude faster than previous approaches. We test the factor-and-solve algorithm with data from several power grids of varying complexity, and we show how the algorithm allows realtime stability assessment of complex power...

  12. Electrical Impedance Tomography Technology

    Data.gov (United States)

    National Aeronautics and Space Administration — The goal for the Electrical Impedance Tomography Technology (EITT) project is to develop a reliable portable, lightweight device providing two-dimensional...

  13. Coupling slots without shunt impedance drop

    International Nuclear Information System (INIS)

    Balleyguier, P.

    1996-01-01

    It is well known that coupling slots between adjacent cells in a π-mode structure reduce shunt impedance per unit length with respect to single cell cavities. To design optimized coupling slots, one has to answer the following question: for a given coupling factor, what shape, dimension, position and number of slots lead to the lowest shunt impedance drop? A numerical study using the 3D code MAFIA has been carried out. The aim was to design the 352 MHz cavities for the high intensity proton accelerator of the TRISPAL project. The result is an unexpected set of four 'petal' slots. Such slots should lead to a quasi-negligible drop in shunt impedance: about -1% on average, for particle velocity from 0.4 c to 0.8 c. (author)

  14. Improvement of force-sensor-based heart rate estimation using multichannel data fusion.

    Science.gov (United States)

    Bruser, Christoph; Kortelainen, Juha M; Winter, Stefan; Tenhunen, Mirja; Parkka, Juha; Leonhardt, Steffen

    2015-01-01

    The aim of this paper is to present and evaluate algorithms for heartbeat interval estimation from multiple spatially distributed force sensors integrated into a bed. Moreover, the benefit of using multichannel systems as opposed to a single sensor is investigated. While it might seem intuitive that multiple channels are superior to a single channel, the main challenge lies in finding suitable methods to actually leverage this potential. To this end, two algorithms for heart rate estimation from multichannel vibration signals are presented and compared against a single-channel sensing solution. The first method operates by analyzing the cepstrum computed from the average spectra of the individual channels, while the second method applies Bayesian fusion to three interval estimators, such as the autocorrelation, which are applied to each channel. This evaluation is based on 28 night-long sleep lab recordings during which an eight-channel polyvinylidene fluoride-based sensor array was used to acquire cardiac vibration signals. The recruited patients suffered from different sleep disorders of varying severity. From the sensor array data, a virtual single-channel signal was also derived for comparison by averaging the channels. The single-channel results achieved a beat-to-beat interval error of 2.2% with a coverage (i.e., percentage of the recording which could be analyzed) of 68.7%. In comparison, the best multichannel results attained a mean error and coverage of 1.0% and 81.0%, respectively. These results present statistically significant improvements of both metrics over the single-channel results (p < 0.05).

  15. High-pressure duo-multichannel soft x-ray spectrometer for tokamak plasma diagnostics

    International Nuclear Information System (INIS)

    Schwob, J.L.; Wouters, A.W.; Suckewer, S.

    1987-03-01

    A high-resolution, time-resolving soft X-ray multichannel spectrometer (SOXMOS) that permits the simultaneous measurement of emission in two different spectral ranges has been developed and tested extensively for tokamak plasma diagnostics. The basic instrument is a high-resolution, interferometrically adjusted, extreme grazing incidence Schwob-Fraenkel duochromator. The instrument is equipped with two multichannel detectors that are adjusted interferometrically and scan along the Rowland circle. Each consists of an MgF 2 coated, funneled microchannel plate, associated with a phosphor screen image intensifier that is coupled to a 1024-element photodiode array by a flexible fibrer optic conduit. The total wavelength coverage of the instrument is 5 to 340 0 A with a measured resolution (FWHM) of about 0.2 A when equipped with a 600 g/mm grating, and 5 to 85 A with a resolution of about 0.06 A using a 2400 g/mm grating. The simultaneous spectral coverage of each detector varies from 15 A at the short wavelength limit to 70 A at the long wavelength limit with the lower dispersion grating. The minimum read-out time for a full spectral portion is 17 ms, but several individual lines can be measured with 1 ms time resolution by selected pixel readout. Higher time resolution can be achieved by replacing one multichannel detector with a single channel electron multiplier detector. Examples of data from the PLT and TFTR tokamaks are presented to illustrate the instrument's versatility, high spectral resolution, and high signal-to-noise ratio even in the 10 A region. 44 refs., 20 figs

  16. A clinical evaluation of the intraluminal bronchial artery infusion with reptilase or plus additional target artery embolization in treatment of severe hemoptysis in patients with pulmonary tuberculosis

    International Nuclear Information System (INIS)

    Lu Puxuan; Cai Xiongmao; Cao Mairui; Yu Weiye; Yang Gendong; Chen Xinchun; Sun Yanzhi; Liu Jinqing; Gong Xiaolong; Fu Xiangdong; Deng Yongcong; Liu Zhi; Zheng Guangping

    2003-01-01

    Objective: To investigate the effect of bronchial artery infusion with Reptilase or plus additional target artery embolization in treatment of massive hemoptysis in patients with pulmonary tuberculosis. Methods: Among 34 patients with massive hemoptysis (≥600 ml/24 hours) resultant from pulmonary tuberculosis, 21 cases (group 1) received by bronchial artery infusion with Reptilase (1-3KU) plus target artery embolization with gelfoam sponge. In the rest 13 cases (group 2) a simple bronchial artery infusion with Reptilase (1-3KU) was performed because the bleeding target arteries were inaccessible. Results: In total 32 cases out of 34 (94.1%) the hemoptysis ceased after the intervention, while 1 case in each group respectively needed further surgery. Among the cured 34 cases, single treatment was done in 32 cases, twice interventions were performed in 1 case and triple intraluminal therapies were done in 1 case. There is no significant difference between the efficiency of the treatment applied in group 1 and group 2 (P>0.05). Conclusion: Bronchial artery infusion with Reptilase or plus additional target artery embolization is effective and safe method in the management of massive hemoptysis in patients with pulmonary tuberculosis. When the target the bleed artery is inaccessible, local intraluminal infusion with Reptilase (1-3KU) is an acceptable option

  17. Impedance calculations for 2-D and 3-D structures and the impedance budget of 7-GeV APS [Advanced Photon Source] storage ring

    International Nuclear Information System (INIS)

    Chou, W.; Jin, Y.

    1989-01-01

    For the storage ring of the 7-GeV Advanced Photon Source (APS), we numerically calculate the longitudinal and the transverse coupling impedances of various kinds of two- and three-dimensional structures. It is shown that the RF cavities are the main contributors to the longitudinal impedance, whereas the transitions between the chamber and the insertion device section dominate the transverse one. Several different numerical approaches are adopted. It is argued that the broadband resonator model may not be appropriate to model the longitudinal impedance. Several interesting phenomena of general interest, including a composition rule and the negative transverse impedance, are discussed. Based on our numerical results and other results available, the impedance budget of the storage ring is established. 9 refs., 8 figs., 1 tab

  18. Detection of irradiated potatoes by impedance measurement

    International Nuclear Information System (INIS)

    Hayashi, T.; Todoriki, S.; Otobe, K.; Sugiyama, J.

    1996-01-01

    Potato is one of the major food items to be treated with ionising radiation and potatoes are irradiated on a large scale in several countries. Every year around 15,000 t of potatoes are irradiated at doses of 60 to 150 Gy (average dose is about 100 Gy) in Japan. Although various methods to detect irradiated potatoes have been investigated, no established method has been reported. Measuring electrical conductivity or impedance of potatoes has been reported as a promising method for the detection of irradiated potatoes. In previous studies it has been found that the ratio of impedance magnitude at 50 kHz to that at 5 kHz, measured immediately after puncturing a potato tuber, is dependent upon the dose applied to the tuber, independent of storage temperature and stable during storage after irradiation. The aim of this study was to establish the optimum conditions for impedance measurement and to examine the applicability of the impedance measuring method to various cultivars (cv.) of potatoes. (author)

  19. On multichannel film dosimetry with channel-independent perturbations

    International Nuclear Information System (INIS)

    Méndez, I.; Peterlin, P.; Hudej, R.; Strojnik, A.; Casar, B.

    2014-01-01

    Purpose: Different multichannel methods for film dosimetry have been proposed in the literature. Two of them are the weighted mean method and the method put forth byMicke et al. [“Multichannel film dosimetry with nonuniformity correction,” Med. Phys. 38, 2523–2534 (2011)] and Mayer et al. [“Enhanced dosimetry procedures and assessment for EBT2 radiochromic film,” Med. Phys. 39, 2147–2155 (2012)]. The purpose of this work was to compare their results and to develop a generalized channel-independent perturbations framework in which both methods enter as special cases. Methods: Four models of channel-independent perturbations were compared: weighted mean, Micke–Mayer method, uniform distribution, and truncated normal distribution. A closed-form formula to calculate film doses and the associated type B uncertainty for all four models was deduced. To evaluate the models, film dose distributions were compared with planned and measured dose distributions. At the same time, several elements of the dosimetry process were compared: film type EBT2 versus EBT3, different waiting-time windows, reflection mode versus transmission mode scanning, and planned versus measured dose distribution for film calibration and for γ-index analysis. The methods and the models described in this study are publicly accessible through IRISEU. Alpha 1.1 ( http://www.iriseu.com ). IRISEU. is a cloud computing web application for calibration and dosimetry of radiochromic films. Results: The truncated normal distribution model provided the best agreement between film and reference doses, both for calibration and γ-index verification, and proved itself superior to both the weighted mean model, which neglects correlations between the channels, and the Micke–Mayer model, whose accuracy depends on the properties of the sensitometric curves. With respect to the selection of dosimetry protocol, no significant differences were found between transmission and reflection mode scanning

  20. On multichannel film dosimetry with channel-independent perturbations

    Energy Technology Data Exchange (ETDEWEB)

    Méndez, I., E-mail: nmendez@onko-i.si; Peterlin, P.; Hudej, R.; Strojnik, A.; Casar, B. [Department of Medical Physics, Institute of Oncology Ljubljana, Zaloška cesta 2, Ljubljana 1000 (Slovenia)

    2014-01-15

    Purpose: Different multichannel methods for film dosimetry have been proposed in the literature. Two of them are the weighted mean method and the method put forth byMicke et al. [“Multichannel film dosimetry with nonuniformity correction,” Med. Phys. 38, 2523–2534 (2011)] and Mayer et al. [“Enhanced dosimetry procedures and assessment for EBT2 radiochromic film,” Med. Phys. 39, 2147–2155 (2012)]. The purpose of this work was to compare their results and to develop a generalized channel-independent perturbations framework in which both methods enter as special cases. Methods: Four models of channel-independent perturbations were compared: weighted mean, Micke–Mayer method, uniform distribution, and truncated normal distribution. A closed-form formula to calculate film doses and the associated type B uncertainty for all four models was deduced. To evaluate the models, film dose distributions were compared with planned and measured dose distributions. At the same time, several elements of the dosimetry process were compared: film type EBT2 versus EBT3, different waiting-time windows, reflection mode versus transmission mode scanning, and planned versus measured dose distribution for film calibration and for γ-index analysis. The methods and the models described in this study are publicly accessible through IRISEU. Alpha 1.1 ( http://www.iriseu.com ). IRISEU. is a cloud computing web application for calibration and dosimetry of radiochromic films. Results: The truncated normal distribution model provided the best agreement between film and reference doses, both for calibration and γ-index verification, and proved itself superior to both the weighted mean model, which neglects correlations between the channels, and the Micke–Mayer model, whose accuracy depends on the properties of the sensitometric curves. With respect to the selection of dosimetry protocol, no significant differences were found between transmission and reflection mode scanning