WorldWideScience

Sample records for monthly monitoring results

  1. First experiences with the Fitmore® hip stem: Early results of the 16-month monitoring

    Directory of Open Access Journals (Sweden)

    Mladenović Marko

    2017-01-01

    Full Text Available Background/Aim. Fitmore® hip stem belongs to the group of short stem prostheses with the metaphysar stabilization, with its shape and form that protects the bone mass in the greater trochanter region and the distal part of the femur. The aim of this paper was to present the early postoperative results in patients with implanted Fitmore® hip stem and point out some of the advantages. Methods. A series of 10 patients with implanted Fitmore® hip stem, was included in this study. The average age of the patients was 54.5 (48–65 years. There were 5 women and 5 men. The total monitoring time was 16 months. To rate the condition of the hip joint we used The Western Ontario and Mc Master Universities Arthritis Index (WOMAC score. We also monitored the degree of hip pain, hip flexion, heterotopic ossification and indentation in the stem of the prosthesis. Results. After 12 months of monitoring 9 (90% of the patients had no pain in the thigh region, and only 1 (10% experienced mild pain. The hip flexion rose from the average 89° to postoperative 114°. WOMAC score rose as well, from 49 to 94 average points. Indentation in the stem was registered 3 months after the operation in 2 (20% of the patients – in one of the patients the indentation was 3 mm and in the other patient 5 mm. After the 16-month monitoring, the results were excellent. The monitoring period was short though it should be continued and the results should be presented after 5 and then after 10 years. Conclusion. Early results of the implantation Fitmore stem showed good bone ingrowth with excellent functional result.

  2. Hydrogeophysical Cyberinfrastructure For Real-Time Interactive Browser Controlled Monitoring Of Near Surface Hydrology: Results Of A 13 Month Monitoring Effort At The Hanford 300 Area

    Science.gov (United States)

    Versteeg, R. J.; Johnson, T.; Henrie, A.; Johnson, D.

    2013-12-01

    . This infrastructure was used for the acquisition and processing of an electrical geophysical timelapse survey which was collected over a highly instrumented field site in the Hanford 300 Area. Over a 13 month period between November 2011 and December 2012 1823 timelapse datasets were collected (roughly 5 datasets a day for a total of 23 million individual measurements) on three parallel resistivity lines of 30 m each with 0.5 meter electrode spacing. In addition, hydrological and environmental data were collected from dedicated and general purpose sensors. This dataset contains rich information on near surface processes on a range of different spatial and temporal scales (ranging from hourly to seasonal). We will show how this cyberinfrastructure was used to manage and process this dataset and how the cyberinfrastructure can be used to access, mine and visualize the resulting data and information.

  3. Undersea acoustic telemetry across the North Anatolian Fault, Marmara Sea: results from the first 6 months of monitoring of the fault displacement

    Science.gov (United States)

    Royer, J. Y.; Deschamps, A.; Piete, H.; Sakic, P.; Ballu, V.; Apprioual, R.; Kopp, H.; Lange, D.; Ruffine, L.; Géli, L.

    2015-12-01

    Located in the Marmara Sea, the Istanbul-Silivri segment of the North Anatolian Fault (NAF) is known to be a seismic gap since 1766, although, in the last century, the NAF has caused major devastating earthquakes over most of its extent. This fault segment, void of seismicity, may be either creeping aseismically or blocked and accumulating enough strain to produce an earthquake of magnitude 7 or greater. This section of the NAF may thus represent a major seismic and tsunamigenic hazard for the Istanbul megalopolis, located only 40 km away. The objective of the MARSITE project, funded by the European Union and coordinated by the Observatory of the University of Kandilli (KOERI), is to determine the blocking state of the Istanbul-Silivri fault segment. In this context, an array of 10 acoustic transponders has been deployed on either sides of the fault, in the eastern part of the Kumburgaz Basin, to measure the displacements of the fault over a period of 3 to 5 years. The telemetric beacons (4 from the University of Brest and 6 from the GEOMAR Institute in Kiel) form two arrays fitted in one another. The principle of the experiment is to repeatedly measure the distance (ie two-way-travel time of acoustic pings) between pairs of beacons and thus to monitor the deformation of an array of 9 baselines, 500m to 3000m long, of which 5 cross obliquely the assumed fault trace. The French and German arrays are independent but ensure a redundancy of rangings along common baselines. Each acoustic transponder also monitors the temperature, pressure, sound-velocity and attitude (tiltmeters), every one or two hours. Data are stored in each beacon and can be downloaded from the surface using an acoustic modem. We present here the first 6 months of recording by the French array, from November 1st, 2014 to April 25, 2015. All acoustic transponders worked nominally for 6 months and appear to have remained stable on the seafloor. Recorded sea-bottom temperatures provide evidence for

  4. BRAVISSIMO: 12-month results from a large scale prospective trial.

    Science.gov (United States)

    Bosiers, M; Deloose, K; Callaert, J; Maene, L; Beelen, R; Keirse, K; Verbist, J; Peeters, P; Schroë, H; Lauwers, G; Lansink, W; Vanslembroeck, K; D'archambeau, O; Hendriks, J; Lauwers, P; Vermassen, F; Randon, C; Van Herzeele, I; De Ryck, F; De Letter, J; Lanckneus, M; Van Betsbrugge, M; Thomas, B; Deleersnijder, R; Vandekerkhof, J; Baeyens, I; Berghmans, T; Buttiens, J; Van Den Brande, P; Debing, E; Rabbia, C; Ruffino, A; Tealdi, D; Nano, G; Stegher, S; Gasparini, D; Piccoli, G; Coppi, G; Silingardi, R; Cataldi, V; Paroni, G; Palazzo, V; Stella, A; Gargiulo, M; Muccini, N; Nessi, F; Ferrero, E; Pratesi, C; Fargion, A; Chiesa, R; Marone, E; Bertoglio, L; Cremonesi, A; Dozza, L; Galzerano, G; De Donato, G; Setacci, C

    2013-04-01

    The BRAVISSIMO study is a prospective, non-randomized, multi-center, multi-national, monitored trial, conducted at 12 hospitals in Belgium and 11 hospitals in Italy. This manuscript reports the findings up to the 12-month follow-up time point for both the TASC A&B cohort and the TASC C&D cohort. The primary endpoint of the study is primary patency at 12 months, defined as a target lesion without a hemodynamically significant stenosis on Duplex ultrasound (>50%, systolic velocity ratio no greater than 2.0) and without target lesion revascularization (TLR) within 12 months. Between July 2009 and September 2010, 190 patients with TASC A or TASC B aortoiliac lesions and 135 patients with TASC C or TASC D aortoiliac lesions were included. The demographic data were comparable for the TASC A/B cohort and the TASC C/D cohort. The number of claudicants was significantly higher in the TASC A/B cohort, The TASC C/D cohort contains more CLI patients. The primary patency rate for the total patient population was 93.1%. The primary patency rates at 12 months for the TASC A, B, C and D lesions were 94.0%, 96.5%, 91.3% and 90.2% respectively. No statistical significant difference was shown when comparing these groups. Our findings confirm that endovascular therapy, and more specifically primary stenting, is the preferred treatment for patients with TASC A, B, C and D aortoiliac lesions. We notice similar endovascular results compared to surgery, however without the invasive character of surgery.

  5. GEOGLAM Crop Monitor Assessment Tool: Developing Monthly Crop Condition Assessments

    Science.gov (United States)

    McGaughey, K.; Becker Reshef, I.; Barker, B.; Humber, M. L.; Nordling, J.; Justice, C. O.; Deshayes, M.

    2014-12-01

    The Group on Earth Observations (GEO) developed the Global Agricultural Monitoring initiative (GEOGLAM) to improve existing agricultural information through a network of international partnerships, data sharing, and operational research. This presentation will discuss the Crop Monitor component of GEOGLAM, which provides the Agricultural Market Information System (AMIS) with an international, multi-source, and transparent consensus assessment of crop growing conditions, status, and agro-climatic conditions likely to impact global production. This activity covers the four primary crop types (wheat, maize, rice, and soybean) within the main agricultural producing regions of the AMIS countries. These assessments have been produced operationally since September 2013 and are published in the AMIS Market Monitor Bulletin. The Crop Monitor reports provide cartographic and textual summaries of crop conditions as of the 28th of each month, according to crop type. This presentation will focus on the building of international networks, data collection, and data dissemination.

  6. Satisfaction of well-controlled type 2 diabetes patients with three-monthly and six-monthly monitoring

    NARCIS (Netherlands)

    Wermeling, Paulien R.; Janssen, Jolien; Gorter, Kees J.; Beulens, Joline W. J.; Rutten, Guy E. H. M.

    2013-01-01

    Background: Patient's satisfaction with monitoring frequency is of interest when implementing six-monthly monitoring for well-controlled type 2 diabetes patients. Here we want to determine the satisfaction of well-controlled type 2 diabetes patients with either three-monthly or six-monthly diabetes

  7. Corral Monitoring System assessment results

    Energy Technology Data Exchange (ETDEWEB)

    Filby, E.E.; Haskel, K.J.

    1998-03-01

    This report describes the results of a functional and operational assessment of the Corral Monitoring Systems (CMS), which was designed to detect and document accountable items entering or leaving a monitored site. Its development was motivated by the possibility that multiple sites in the nuclear weapons states of the former Soviet Union might be opened to such monitoring under the provisions of the Strategic Arms Reduction Treaty. The assessment was performed at three levels. One level evaluated how well the planned approach addressed the target application, and which involved tracking sensitive items moving into and around a site being monitored as part of an international treaty or other agreement. The second level examined the overall design and development approach, while the third focused on individual subsystems within the total package. Unfortunately, the system was delivered as disassembled parts and pieces, with very poor documentation. Thus, the assessment was based on fragmentary operating data coupled with an analysis of what documents were provided with the system. The system design seemed to be a reasonable match to the requirements of the target application; however, important questions about site manning and top level administrative control were left unanswered. Four weaknesses in the overall design and development approach were detected: (1) poor configuration control and management, (2) inadequate adherence to a well defined architectural standard, (3) no apparent provision for improving top level error tolerance, and (4) weaknesses in the object oriented programming approach. The individual subsystems were found to offer few features or capabilities that were new or unique, even at the conceptual level. The CMS might possibly have offered a unique combination of features, but this level of integration was never realized, and it had no unique capabilities that could be readily extracted for use in another system.

  8. Surgical crown lengthening: a 12-month study - radiographic results

    Directory of Open Access Journals (Sweden)

    Daniela Eleutério Diniz

    2007-08-01

    Full Text Available OBJECTIVE: The purpose of this study was to perform a radiographic follow-up evaluation after a 12-month healing period, following crown lengthening surgery. MATERIAL AND METHODS: Twenty-three periodontally healthy subjects (mean age 32.5 years that required crown lengthening surgery in premolars were recruited. In a total of 30 premolars, full thickness flaps, osseous resection, and flap suturing were performed. The restorative margin was defined in the pre-surgical phase and maintained unaltered during the healing period, serving as a reference point. Standardized bitewing radiographs were taken before and after osseous reduction, and at 2, 3, 6, and 12-month healing periods. RESULTS: Intact lamina dura was observed at both mesial and distal alveolar crests only from the 3rd month. At 12-months, all alveolar crests presented lamina dura. The overall mean distance from the restorative margin to the alveolar crest achieved after osseous resection was 3.28±0.87 mm at mesial and 2.81±0.51 mm at distal sites. No significant radiographic changes in the bone crest were observed during a 12-month healing period. CONCLUSION: The findings of this study suggest that the radiographic proximal bone level observed on bitewing radiographs following crown lengthening surgery can be used as a reference to predict the future level of the healed alveolar crest.

  9. SURGICAL CROWN LENGTHENING: A 12-MONTH STUDY - RADIOGRAPHIC RESULTS*

    Science.gov (United States)

    Diniz, Daniela Eleutério; Okuda, Kalizia Marcela; Fonseca, Clarissa Ribeiro; Gonzalez, Marly Kimie Sonohara; Greghi, Sebastião Luiz Aguiar; do Valle, Accácio Lins; Lauris, José Roberto Pereira

    2007-01-01

    Objective The purpose of this study was to perform a radiographic follow-up evaluation after a 12-month healing period, following crown lengthening surgery. Material and methods Twenty-three periodontally healthy subjects (mean age 32.5 years) that required crown lengthening surgery in premolars were recruited. In a total of 30 premolars, full thickness flaps, osseous resection, and flap suturing were performed. The restorative margin was defined in the pre-surgical phase and maintained unaltered during the healing period, serving as a reference point. Standardized bitewing radiographs were taken before and after osseous reduction, and at 2, 3, 6, and 12-month healing periods. Results Intact lamina dura was observed at both mesial and distal alveolar crests only from the 3rd month. At 12-months, all alveolar crests presented lamina dura. The overall mean distance from the restorative margin to the alveolar crest achieved after osseous resection was 3.28±0.87 mm at mesial and 2.81±0.51 mm at distal sites. No significant radiographic changes in the bone crest were observed during a 12-month healing period. Conclusion The findings of this study suggest that the radiographic proximal bone level observed on bitewing radiographs following crown lengthening surgery can be used as a reference to predict the future level of the healed alveolar crest. PMID:19089145

  10. This Month in Astronomical History: Preliminary Survey Results

    Science.gov (United States)

    Wilson, Teresa

    2017-01-01

    This Month in Astronomical History is a short (~500 word) column on the AAS website that revisits significant astronomical events or the lives of people who have made a large impact on the field. The monthly column began in July 2016 at the request of the Historical Astronomical Division. Examples of topics that have been covered include Comet Shoemaker-Levy’s collision with Jupiter, the discovery of the moons of Mars, the life of Edwin Hubble, Maria Mitchell’s comet discovery, and the launch of Sputnik II. A survey concerning the column is in progress to ensure the column addresses the interests and needs of a broad readership, including historians, educators, research astronomers, and the general public. Eleven questions focus on the style and content of the column, while eight collect simple demographics. The survey has been available on the AAS website since and was mentioned in several AAS newsletters; however, non-members of AAS were also recruited to include respondents from a variety of backgrounds. Preliminary results of the survey are presented and will be used to hone the style and content of the column to serve the widest possible audience. Responses continue to be collected at: https://goo.gl/forms/Lhwl2aWJl2Vkoo7v1

  11. Photorefractive keratectomy for myopia: 6-month results in 95 eyes.

    Science.gov (United States)

    Tutton, M K; Ramsell, T G; Garston, J B; Tolia, J J; Banerjee, D K; Adhikary, H P; Birch, M; Cherry, P M; Neave, C G; Fichte, C M

    1993-01-01

    Ninety-five eyes of 91 patients with myopia from -1.00 to -6.00 D (mean -3.40 D, +/- 1.2) were treated with an ExciMed UV2OOLA 193-nanometer excimer laser (Summit Technology, Inc, Waltham, Mass) (with version 5.5 software) with a 5-millimeter ablation zone. At 6 months, 67 eyes (70%) were within +/- 0.50 D, 84 eyes (88%) were within +/- 1.00 D, and 94 eyes (99%) were within +/- 2.00 D. There was an average overcorrection of +0.25 D which had decreased to +0.18 D by 9 months. Best spectacle corrected visual acuity was 6/6 or better in 88 eyes (94%) and six eyes (6%) had a corrected visual acuity of 6/9. Fifty percent of eyes had slight astigmatism (mean 0.68 D, range 0.25 to 2.00 D) and this reduced to 0.33D (0.02 > p > 0.01) at 6 months.

  12. Towards a more efficient diabetes control in primary care: six-monthly monitoring compared with three-monthly monitoring in type 2 diabetes - The EFFIMODI trial. Design of a randomised controlled patient-preference equivalence trial in primary care

    Directory of Open Access Journals (Sweden)

    Ardine de Wit G

    2010-05-01

    Full Text Available Abstract Background Scientific evidence for the frequency of monitoring of type 2 diabetes patients is lacking. If three-monthly control in general practice could be reduced to six-monthly control in some patients, this would on the one hand reduce the use of medical services including involvement of practice nurses, and thus reduce costs, and on the other hand alleviate the burden of people with type 2 diabetes. The goal of this study is to make primary diabetes care as efficient as possible for patients and health care providers. Therefore, we want to determine whether six-monthly monitoring of well-controlled type 2 diabetes patients in primary care leads to equivalent cardiometabolic control compared to the generally recommended three-monthly monitoring. Methods and design The study is a randomised controlled patient-preference equivalence trial. Participants are asked if they prefer three-monthly (usual care or six-monthly diabetes monitoring. If they do not have a preference, they are randomised to a three-monthly or six-monthly monitoring group. Patients are eligible for the study if they are between 40 and 80 years old, diagnosed with type 2 diabetes more than one year ago, treated by a general practitioner, not on insulin treatment, and with HbA1c ≤7.5%, systolic blood pressure ≤145 mmHg and total cholesterol ≤5.2 mmol/l. The intervention group (six-monthly monitoring will receive the same treatment with the same treatment targets as the control group (three-monthly monitoring. The intervention period will last one and a half year. After the intervention, the three-monthly and six-monthly monitoring groups are compared on equivalence of cardiometabolic control. Secondary outcome measures are HbA1c, blood pressure, cholesterol level, Body Mass Index, smoking behaviour, physical activity, loss of work due to illness, health status, diabetes-specific distress, satisfaction with treatment and adherence to medications. We will use

  13. October 2008 monitoring results for Morrill, Kansas.

    Energy Technology Data Exchange (ETDEWEB)

    LaFreniere, L. M.; Environmental Science Division

    2009-03-10

    In September 2005, the Commodity Credit Corporation of the U.S. Department of Agriculture (CCC/USDA) initiated periodic sampling of groundwater in the vicinity of a grain storage facility formerly operated by the CCC/USDA at Morrill, Kansas. The sampling at Morrill is being performed on behalf of the CCC/USDA by Argonne National Laboratory, in accord with a monitoring program approved by the Kansas Department of Health and Environment (KDHE 2005), to monitor levels of carbon tetrachloride contamination identified in the groundwater at this site (Argonne 2004, 2005a). This report provides results for the most recent monitoring event, in October 2008. Under the KDHE-approved monitoring plan (Argonne 2005b), groundwater was initially sampled twice yearly for a period of two years (in fall 2005, in spring and fall 2006, and in spring and fall 2007). The samples were analyzed for volatile organic compounds (VOCs), as well as for selected geochemical parameters to aid in the evaluation of possible natural contaminant degradation (reductive dechlorination) processes in the subsurface environment. During the two-year period, the originally approved scope of the monitoring was expanded to include vegetation sampling (initiated in October 2006) and surface water and stream bed sediment sampling (initiated in March 2007, after a visual reconnaissance along Terrapin Creek [Argonne 2007a]). The analytical results for groundwater sampling events at Morrill in September 2005, March and September 2006, March and October 2007, and April 2008 were documented previously (Argonne 2006a,b, 2007b, 2008a,c). Those results consistently demonstrated the presence of carbon tetrachloride contamination, at levels exceeding the KDHE Tier 2 risk-based screening level (5.0 {micro}g/L) for this compound, in a groundwater plume extending generally south-southeastward from the former CCC/USDA facility, toward Terrapin Creek at the south edge of the town. Low levels ({le} 1.3 {micro}g/L) of carbon

  14. The Stockholm Diabetes Intervention Study (SDIS): 18 months' results.

    Science.gov (United States)

    Reichard, P; Britz, A; Cars, I; Nilsson, B Y; Sobocinsky-Olsson, B; Rosenqvist, U

    1988-01-01

    Patients with insulin-dependent diabetes mellitus (IDDM), non-proliferative retinopathy and unsatisfactory blood glucose control were randomized to intensified conventional treatment (ICT, 48 patients) or regular treatment (RT, 54 patients) for a 5-year study. After 18 months the glycosylated hemoglobin (HbA1c) was reduced in both groups, but significantly more in the ICT group (p = 0.00005). Thirty of the RT patients and 16 from the ICT group deteriorated as to retinopathy (p = 0.024). Microalbuminuria appeared more often in the RT patients (p = 0.023), and nerve conduction velocities were significantly reduced only in the RT group (p between 0.0005 and 0.047). Serious hypoglycemia was more common in the ICT patients (p = 0.003). The progression of diabetic late complications was thus slowed down by intensified treatment, but at the price of an increased frequency of serious hypoglycemia.

  15. Biomass gasification: field monitoring results (Part II)

    NARCIS (Netherlands)

    Mendis, M.S.; Stassen, H.E.M.; Stiles, H.N.

    1989-01-01

    This paper continues the review of gasifier monitoring results by presenting details from units in Vanuatu and in Mali. A presentation of all the data in a summarised form is made and the advantages and dangers of installation evaluation based on data in such a form are highlighted. Values, typical

  16. Language Assessment in a Snap: Monitoring Progress up to 36 Months

    Science.gov (United States)

    Gilkerson, Jill; Richards, Jeffrey A.; Greenwood, Charles R.; Montgomery, Judy K.

    2017-01-01

    This article describes the development and validation of the Developmental Snapshot, a 52-item parent questionnaire on child language and vocal communication development that can be administered monthly and scored automatically. The Snapshot was created to provide an easily administered monthly progress monitoring tool that enables parents to…

  17. October 2008 monitoring results for Barnes, Kansas.

    Energy Technology Data Exchange (ETDEWEB)

    LaFreniere, L. M.; Environmental Science Division

    2009-02-26

    The Commodity Credit Corporation of the U.S. Department of Agriculture (CCC/USDA) operated a grain storage facility at Barnes, Kansas, during most of the interval 1949-1974. Carbon tetrachloride contamination was initially detected in 1986 in the town's public water supply wells. In 2006-2007, the CCC/USDA conducted a comprehensive targeted investigation at and near its former property in Barnes to characterize this contamination. Those results were reported previously (Argonne 2008a). In November 2007, the CCC/USDA began quarterly groundwater monitoring at Barnes. The monitoring is being conducted on behalf of the CCC/USDA by Argonne National Laboratory, in accord with the recommendations made in the report for the 2006-2007 targeted investigation (Argonne 2008a). The objective is to monitor the carbon tetrachloride contamination identified in the groundwater at Barnes. The sampling is presently conducted in a network of 28 individual monitoring wells (at 19 distinct locations), 2 public water supply wells, and 1 private well (Figure 1.1). The results of the 2006-2007 targeted investigation and the subsequent monitoring events in November 2007 (Argonne 2008b), March 2008 (Argonne 2008c), and July 2008 (Argonne 2008d) demonstrated the presence of carbon tetrachloride contamination in groundwater at levels exceeding the Kansas Department of Health and Environment (KDHE) Tier 2 risk-based screening level (RBSL) of 5.0 {micro}g/L for this compound. The contaminant plume appears to extend from the former CCC/USDA property northwestward, toward the Barnes public water supply wells. Information obtained during the 2006-2007 investigations indicates that at least one other potential source might have contributed to the groundwater contaminant plume (Argonne 2008a). The former agriculture building owned by the local school district, located immediately east of well PWS3, is also a potential source of the contamination. This current report presents the results of the

  18. Analytical results from routine DSSHT and SEHT monthly samples

    Energy Technology Data Exchange (ETDEWEB)

    Peters, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-12-01

    Strip Effluent Hold Tank (SEHT) and Decontaminated Salt Solution Hold Tank (DSSHT) samples from several of the “microbatches” of Integrated Salt Disposition Project (ISDP) Salt Batch (“Macrobatch”) 8B have been analyzed for 238Pu, 90Sr, 137Cs, cations (Inductively Coupled Plasma Emission Spectroscopy - ICPES), and anions (Ion Chromatography Anions - IC-A). The analytical results from the current microbatch samples are similar to those from previous macrobatch samples. The Cs removal continues to be excellent, with decontamination factors (DF) averaging 22,100 (114% RSD). The bulk chemistry of the DSSHT and SEHT samples do not show any signs of unusual behavior, other than lacking the anticipated degree of dilution that is calculated to occur during Modular Caustic-Side Solvent Extraction Unit (MCU) processing.

  19. Analytical Results from Routine DSSHT and SEHT Monthly Samples

    Energy Technology Data Exchange (ETDEWEB)

    Peters, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-08-17

    Strip Effluent Hold Tank (SEHT) and Decontaminated Salt Solution Hold Tank (DSSHT) samples from several of the “microbatches” of Integrated Salt Disposition Project (ISDP) Salt Batch (“Macrobatch”) 8B have been analyzed for 238Pu, 90Sr, 137Cs, cations (Inductively Coupled Plasma Emission Spectroscopy - ICPES), and anions (Ion Chromatography Anions - IC-A). The analytical results from the current microbatch samples are similar to those from previous macrobatch samples. The Actinide Removal Process (ARP) and the Modular Caustic-Side Solvent Extraction Unit (MCU) continue to show more than adequate Pu and Sr removal for times when monosodium titanate (MST) is used. Even with no MST strike being performed there exists some small Pu and Sr removal, likely from filtration of fines containing these elements. The Cs removal continues to be excellent, with decontamination factors (DF) averaging 16,400. The bulk chemistry of the DSSHT and SEHT samples do not show any signs of unusual behavior. SRNL recommends that a sample of the strip feed be analyzed for cation and anion content if a further decline in boron concentration is noted in future SEHT samples.

  20. Wide Area Wind Field Monitoring Status & Results

    Energy Technology Data Exchange (ETDEWEB)

    Alan Marchant; Jed Simmons

    2011-09-30

    Volume-scanning elastic has been investigated as a means to derive 3D dynamic wind fields for characterization and monitoring of wind energy sites. An eye-safe volume-scanning lidar system was adapted for volume imaging of aerosol concentrations out to a range of 300m. Reformatting of the lidar data as dynamic volume images was successfully demonstrated. A practical method for deriving 3D wind fields from dynamic volume imagery was identified and demonstrated. However, the natural phenomenology was found to provide insufficient aerosol features for reliable wind sensing. The results of this study may be applicable to wind field measurement using injected aerosol tracers.

  1. SENTINEL-1 RESULTS: SEA ICE OPERATIONAL MONITORING

    DEFF Research Database (Denmark)

    Toudal Pedersen, Leif; Saldo, Roberto; Fenger-Nielsen, Rasmus

    2015-01-01

    In the present paper we demonstrate the capabilities of the Sentinel-1 SAR data for operational sea-ice and iceberg monitoring. Most of the examples are drawn from the Copernicus Marine Environmental Monitoring Service (CMEMS) production.......In the present paper we demonstrate the capabilities of the Sentinel-1 SAR data for operational sea-ice and iceberg monitoring. Most of the examples are drawn from the Copernicus Marine Environmental Monitoring Service (CMEMS) production....

  2. Below the knee PTA in critical limb ischemia results after 12 months: Single center experience

    Energy Technology Data Exchange (ETDEWEB)

    Balzer, Joern O., E-mail: balzerjo@t-online.d [Dept. for Radiology and Nuclear medicine, Catholic Clinic Mainz, An der Goldgrube 11, Mainz 55131 (Germany); Khan, Verena [Dept. of Diagnostic and Interventional Radiology, Clinic Nurnberg North (Germany); Thalhammer, Axel; Vogl, Thomas J.; Lehnert, Thomas [Dept. of Diagnostic and Interventional Radiology, Univ. Clinic, Johann Wolfgang Goethe-University Frankfurt/Main (Germany)

    2010-07-15

    Purpose: Evaluation of angioplasty with bare metal stents in infrapopliteal occlusions or severe stenoses in patients with critical limb ischemia. Material and methods: Percutaneous stent angioplasty was performed in 58 limbs in 47 patients with critical limb ischemia (CLI) in Rutherford stage 4-6. Lesions with up to 5 cm in length with at least one patent vessel below the obstruction were treated. 121 bare metal stents (diameter of 2.5-4 mm; length of 18-38 mm) were implanted. Follow-up examinations were performed up to 12 months postinterventionally using clinical examination, ABI calculation, and color-coded duplex sonography. Patency rates were calculated on the basis of the Kaplan-Meier analysis. Results: Technical success was achieved in 100%. Minor complications (hematoma, distal emboli, vessel dissection) were documented in 5.17% (n = 3) limbs, respectively. The 3-month, 6-month, and 1-year primary patency rate was 93.0%, 78.9% and 66.7%, respectively. 86.9% of the lesions healed postinterventionally. The cumulative limb salvage rate was 96.6%. Conclusion: Stent angioplasty in infrapopliteal arteries is a safe and effective technique for the treatment of patients with CLI. By consequent clinical monitoring high secondary patency rates can be achieved. The use of a bare metal stent seems to result in high limb salvage, primary and secondary patency rates in the mid-term follow-up.

  3. Monitoring results of two PBS demonstration vehicles in the forestry industry in South Africa

    CSIR Research Space (South Africa)

    Nordengen, Paul A

    2010-03-01

    Full Text Available commissioned. Data including payload per trip, average trip speeds, kilometres travelled per month, average monthly fuel consumption, maintenance costs and records of incidents and accidents are collected on a monthly basis. 3.1 Payload During...: Monitoring results of two PBS vehicles in South Africa 6 3.2 Fuel Efficiency From a productivity perspective, fuel efficiency is one of the most important parameters to monitor. This section describes the performance of the PBS vehicles compared...

  4. Monitoring the NOAA Operational VIIRS RSB and DNB Calibration Stability Using Monthly and Semi-Monthly Deep Convective Clouds Time Series

    Directory of Open Access Journals (Sweden)

    Wenhui Wang

    2016-01-01

    Full Text Available The Visible and Infrared Imaging Radiometer Suite (VIIRS onboard the Joint Polar Satellite System (JPSS/Suomi National Polar-Orbiting Partnership (SNPP satellite provide sensor data records for the retrievals of many environment data records. It is critical to monitor the VIIRS long-term calibration stability to ensure quality EDR retrieval. This study investigates the radiometric calibration stability of the NOAA operational SNPP VIIRS Reflective Solar Bands (RSB and Day-Night-Band (DNB using Deep Convective Clouds (DCC. Monthly and semi-monthly DCC time series for 10 moderate resolution bands (M-bands, M1–M5 and M7–M11, March 2013–September 2015, DNB (March 2013–September 2015, low gain stage, and three imagery resolution bands (I-bands, I1–I3, January 2014–September 2015 were developed and analyzed for long-term radiometric calibration stability monitoring. Monthly DCC time series show that M5 and M7 are generally stable, with a stability of 0.4%. DNB has also been stable since May 2013, after its relative response function update, with a stability of 0.5%. The stabilities of M1–M4 are 0.6%–0.8%. Large fluctuations in M1–M4 DCC reflectance were observed since early 2014, correlated with F-factor (calibration coefficients trend changes during the same period. The stabilities of M8-M11 are from 1.0% to 3.1%, comparable to the natural DCC variability at the shortwave infrared spectrum. DCC mean band ratio time series show that the calibration stabilities of I1–I3 follow closely with M5, M7, and M10. Relative calibration changes were observed in M1/M4 and M5/M7 DCC mean band ratio time series. The DCC time series are generally consistent with results from the VIIRS validation sites and VIIRS/MODIS (the Moderate-resolution Imaging Spectroradiometer simultaneous nadir overpass time series. Semi-monthly DCC time series for RSB M-bands and DNB were compared with monthly DCC time series. The results indicate that semi-monthly DCC

  5. Preliminary 6 month results from the Argus II epiretinal prosthesis feasibility study.

    Science.gov (United States)

    Humayun, Mark S; Dorn, Jessy D; Ahuja, Ashish K; Caspi, Avi; Filley, Eugene; Dagnelie, Gislin; Salzmann, Joël; Santos, Arturo; Duncan, Jacque; daCruz, Lyndon; Mohand-Said, Saddek; Eliott, Dean; McMahon, Matthew J; Greenberg, Robert J

    2009-01-01

    The Argus II 60 channel epiretinal prosthesis has been developed in order to provide partial restoration of vision to subjects blinded from outer retinal degenerative disease. To date the device has been implanted in 21 subjects as part of a feasibility study. In 6 month post-implantation door finding and line tracking orientation and mobility testing, subjects have shown improvements of 86% and 73%, respectively, for system on vs. system off. In high-contrast Square Localization tests using a touch screen monitor 87% of tested subjects performed significantly better with the system on compared with off. These preliminary results show that the Argus II system provides some functional vision to blind subjects.

  6. Test Results of a Phi Monitoring System

    CERN Document Server

    Figueroa, Carlos; Burgos, C; Ferrrando, A; Matorras, Francisco; Molinero, Antonio; Rodriguo, T; Shvachkin, V

    1997-01-01

    The development and tests of a Phi monitoring system prototype designed for the CMS Muon Spectrometer alignment are described. The system, using a sweeping laser beam, defines a light reference plane to be used for the continuous monitoring of the Muon detectors. The performance of the system in the Laboratory was satisfactory. It showed good stability and linearity response behaviour. With the appropriate selection of components it can monitor large range position shifts ( up to 1-2 cm) with good accuracy at long distances ( ~ 60 mu accuracy at 10 m).

  7. 40 CFR 141.706 - Reporting source water monitoring results.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Reporting source water monitoring... Cryptosporidium Source Water Monitoring Requirements § 141.706 Reporting source water monitoring results. (a) Systems must report results from the source water monitoring required under § 141.701 no later than 10...

  8. INCIDENCE AND SURVIVAL OF LIPOLYTIC ORGANISMS MONITORED FOR TWELVE MONTHS IN DOMESTIC WASTEWATER AND RECEIVING STREAM

    OpenAIRE

    Adebowale Odeyemi; Babatunde Aderiye

    2013-01-01

    The incidence and survival of lipolytic organisms in domestic wastewater and receiving stream were monitored over 12 months. The average total bacterial count in the wastewater samples reduced in April and November by 24.2% and 41.6% respectively. There was also a reduction of 42.3% and 60.1% in the load in the receiving stream in August and July. Subsequently, at 5m downstream from the entry of the wastewater the microbial load reduced in March (19.2%) and June (19.2%). However, the occurren...

  9. Outcome after major trauma: 12-month and 18-month follow-up results from the Trauma Recovery Project.

    Science.gov (United States)

    Holbrook, T L; Anderson, J P; Sieber, W J; Browner, D; Hoyt, D B

    1999-05-01

    The importance of outcome after major injury has continued to gain attention in light of the ongoing development of sophisticated trauma care systems in the United States. The Trauma Recovery Project (TRP) is a large prospective epidemiologic study designed to examine multiple outcomes after major trauma in adults aged 18 years and older, including quality of life, functional outcome, and psychologic sequelae such as depression and posttraumatic stress disorder (PTSD). Patient outcomes were assessed at discharge and at 6, 12, and 18 months after discharge. The specific objectives of the present report are to describe functional outcomes at the 12-month and 18-month follow-ups in the TRP population and to examine the association of putative risk factors with functional outcome. Between December 1, 1993, and September 1, 1996, 1,048 eligible trauma patients triaged to four participating trauma center hospitals in the San Diego Regionalized Trauma System were enrolled in the TRP study. The admission criteria for patients were as follows: (1) age 18 years or older; (2) Glasgow Coma Scale score on admission of 12 or greater; and (3) length of stay greater than 24 hours. Functional outcome after trauma was measured before and after injury using the Quality of Well-Being (QWB) Scale, an index sensitive to the well end of the functioning continuum (0 = death, 1.000 = optimum functioning). Follow-up at 12 months after discharge was completed for 806 patients (79%), and follow-up at 18 months was completed for 780 patients (74%). Follow-up contact at any of the study time points (6, 12, or 18 months) was achieved for 926 (88%) patients. The mean age was 36 +/- 14.8 years, and 70% of the patients were male; 52% were white, 30% were Hispanic, and 18% were black or other. Less than 40% of study participants were married or living together. The mean Injury Severity Score was 13 +/- 8.5, with 85% blunt injuries and a mean length of stay of 7 +/- 9.2 days. QWB scores before injury

  10. The questioning for routine monthly monitoring of proteinuria in patients with β-thalassemia on deferasirox chelation.

    Science.gov (United States)

    Bayhan, Turan; Ünal, Şule; Ünlü, Ozan; Küçüker, Hakan; Tutal, Anıl Doğukan; Karabulut, Erdem; Gümrük, Fatma

    2017-05-01

    Iron chelation therapy is one of the mainstays of the management of the patients with β-thalassemia (BT) major. Deferasirox is an oral active iron chelating agent. Proteinuria is one of the potential renal adverse effects of deferasirox, and monthly follow-up for proteinuria is suggested by Food and Drug Administration and European Medicine Agency. We aimed to investigate the necessity for monthly monitoring for proteinuria among patients with BT on deferasirox. A retrospective laboratory and clinic data review was performed for patients with BT major or intermedia who were treated with deferasirox chelation therapy. All patients were monitored for proteinuria for every 3 or 4 weeks after the initiation of deferasirox with serum creatinine and spot urine protein/creatinine ratios. The median follow-up time of the 37 (36 BT major and one BT intermedia) patients was 44 months. Seven patients (18.9%) developed significant proteinuria (ratio ≥0.8). Of the 1490 measurements, 12 tests (0.8%) were proteinuric. Urine proteinuria resolved in all of the patients during the follow-up. The risk of proteinuria was higher at ages below a cut-off point of 23 years (p = 0.019). Patients, who were on deferasirox at doses above a cut-off dose of 29 mg/kg/day, were found to have higher risk of proteinuria development (p = 0.004). Proteinuria resolves without any complication or major intervention according to our results. Potentially more risky groups (age below 23 years old and receivers above a dose of 29 mg/kg/day) might be suggested to be followed monthly, besides monitoring all of the patients.

  11. INCIDENCE AND SURVIVAL OF LIPOLYTIC ORGANISMS MONITORED FOR TWELVE MONTHS IN DOMESTIC WASTEWATER AND RECEIVING STREAM

    Directory of Open Access Journals (Sweden)

    Adebowale Odeyemi

    2013-10-01

    Full Text Available The incidence and survival of lipolytic organisms in domestic wastewater and receiving stream were monitored over 12 months. The average total bacterial count in the wastewater samples reduced in April and November by 24.2% and 41.6% respectively. There was also a reduction of 42.3% and 60.1% in the load in the receiving stream in August and July. Subsequently, at 5m downstream from the entry of the wastewater the microbial load reduced in March (19.2% and June (19.2%. However, the occurrence of coliforms was more affected in the months of May (53% to July (87.2%. At 5m and 10m downstream the coliform population reduced by 27.9% and 30.1% respectively. Of the twelve (12 bacterial isolates obtained at the exit of the wastewater into the receiving stream, only four (4 were found to possess lipolytic activity. These include the species of Enterococcus, Klebsiella, Pseudomonas and Staphylococcus. There was no significant difference in the amount of nutrients found in the domestic wastewater and receiving stream during the months. This paper also discusses the implication of disposing large amounts of wastewater effluents into the receiving water and the need to remedy and minimize the overall impact of such pollution on the environment.

  12. Monitoring Attention During Operant Conditioning in Six and Seven Month Old Infants.

    Science.gov (United States)

    Strain, Barbara; Vietze, Peter M.

    The purpose of the present study was to investigate more directly the effects of content and repetition of contingent visual feedback on a discrete operant pulling response and accompanying visual attention in 24 six- to seven-month old infants. Simultaneous recording was made of infant operant behavior and visual attention. Results indicated…

  13. Effect of smoking cessation on non-surgical periodontal therapy: Results after 24 months

    DEFF Research Database (Denmark)

    Francisca Rosa, Ecinele; Corraini, Priscila; Inoue, Gislene

    2014-01-01

    AIM: The aim of this 24-month prospective study was to assess the effect of smoking cessation on non-surgical periodontal therapy (NSPT) in adult subjects with chronic periodontitis. MATERIALS AND METHODS: Relative to a previous 12-month follow-up study, recruitment and follow-up period were...... extended, resulting in 116 eligible among the 286 screened subjects. They received NSPT and concurrent smoking cessation interventions. Periodontal maintenance was performed every three months. A calibrated examined, blinded to smoking status, performed full-mouth periodontal examination in six sites per...... continued smoking (NQ) and 11 oscillated (O) at 24 months of follow-up. Thereby, Q showed significantly higher mean CAL gain in diseased sites and higher reduction in sites with CAL ≥ 3 mm, when compared to NQ. In addition, Q presented significantly higher mean probing depth reduction relative to NQ(p≤ 0...

  14. Transepithelial corneal collagen crosslinking for progressive keratoconus: 24-month clinical results.

    Science.gov (United States)

    Caporossi, Aldo; Mazzotta, Cosimo; Paradiso, Anna Lucia; Baiocchi, Stefano; Marigliani, Davide; Caporossi, Tomaso

    2013-08-01

    To assess the clinical results of transepithelial collagen crosslinking (CXL) in patients 26 years and younger with progressive keratoconus suitable for epithelium-off (epi-off) CXL. Department of Ophthalmology, Siena University Hospital, Siena, Italy. Prospective case series. The study included 26 eyes (26 patients) treated by transepithelial (epithelium-on) CXL. The mean age was 22 years (range 11 to 26 years) (10 younger than 18 years; 16 between 19 years and 26 years). Preoperative and postoperative examinations included uncorrected (UDVA) and corrected (CDVA) distance visual acuities, simulated maximum keratometry (K), coma and spherical aberration, and corneal optical coherence tomography optical pachymetry. The solution for transepithelial CXL (Ricrolin TE) comprised riboflavin 0.1%, dextran 15.0%, trometamol (Tris), and ethylenediaminetetraacetic acid. Ultraviolet-A treatment was performed with the Caporossi Baiocchi Mazzotta X Linker Vega at 3 mW/cm(2). After relative improvement in the first 3 to 6 months, the UDVA and CDVA gradually returned to baseline preoperative values. After 12 months of stability, the simulated maximum K value worsened at 24 months. Coma aberration showed no statistically significant change. Spherical aberration increased at 24 months. Pachymetry showed a progressive, statistically significant decrease at 24 months. Fifty percent of pediatric patients were retreated with epi-off CXL due to significant deterioration of all parameters after 12 months of follow-up. Functional results after transepithelial CXL showed keratoconus instability, in particular in pediatric patients 18 years old and younger; there was also functional regression in patients between 19 years and 26 years old after 24 months of follow-up. mentioned. Copyright © 2013 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  15. Monthly results of measurements: Apr 1997; Tableaux mensuels des mesures. Avril 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  16. Monthly results of measurements: November 1994; Tableaux mensuels des mesures. Novembre 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  17. Monthly results of measurements: June 1995; Tableaux mensuels des mesures. Juin 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  18. Monthly results of measurements: February 1996; Tableaux mensuels des mesures. Fevrier 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  19. Monthly results of measurements: March 1997; Tableaux mensuels des mesures. Mars 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  20. Monthly results of measurements: July 1995; Tableaux mensuels des mesures. Juillet 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  1. Monthly results of measurements. January 1996; Tableaux mensuels des mesures. Janvier 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  2. Monthly results of measurements. July 1996; Tableaux mensuels des mesures. juillet 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  3. Monthly results of measurements: November 1995; Tableaux mensuels des mesures. Novembre 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  4. Monthly results of measurements: Jan 2001; Tableaux mensuels des mesures. Janvier 2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  5. Monthly results of measurements: Aug 2000; Tableaux mensuels des mesures. Aout 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  6. Monthly results of measurements: Feb 2001; Tableaux mensuels des mesures. Fevrier 2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  7. Monthly results of measurements: May 2000; Tableaux mensuels des mesures. Mai 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  8. Monthly results of measurements: Jan 2000; Tableaux mensuels des mesures. Janvier 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  9. Monthly results of measurements: July 2000; Tableaux mensuels des mesures. Juillet 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  10. Monthly results of measurements: April 2000; Tableaux mensuels des mesures. Avril 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  11. Monthly results of measurements: Mar 2001; Tableaux mensuels des mesures. Mars 2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  12. Monthly results of measurements: Dec 2000; Tableaux mensuels des mesures. Decembre 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  13. Monthly results of measurements: Mars 2000; Tableaux mensuels des mesures. Mars 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  14. Monthly results of measurements: Apr 2001; Tableaux mensuels des mesures. Avril 2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  15. Monthly results of measurements: Sep 2000; Tableaux mensuels des mesures. Septembre 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  16. Monthly results of measurements: Feb 2000; Tableaux mensuels des mesures. Fevrier 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  17. Monthly results of measurements: June 2000; Tableaux mensuels des mesures. Juin 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  18. Monthly results of measurements: Nov 2000; Tableaux mensuels des mesures. Novembre 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  19. Monthly results of measurements: October 1996; Tableaux mensuels des mesures. Octobre 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  20. Monthly results of measurements: January 1998; Tableaux mensuels des mesures. Janvier 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables

  1. Monthly results of measurements: January 1995; Tableaux mensuels des mesures. Janvier 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  2. Monthly results of measurements: Aug 1997; Tableaux mensuels des mesures. Aout 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables

  3. Monthly results of measurements: December 1994; Tableaux mensuels des mesures. Decembre 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  4. Monthly results of measurements. May 1996; Tableaux mensuels des mesures. Mai 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  5. Monthly results of measurements: August 1995; Tableaux mensuels des mesures. Aout 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  6. Monthly results of measurements: July 1997; Tableaux mensuels des mesures. Juillet 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables

  7. Monthly results of measurements: Jun 1998; Tableaux mensuels des mesures. Juin 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  8. Monthly results of measurements: September 1995; Tableaux mensuels des mesures. Septembre 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  9. Monthly results of measurements: October 1998; Tableaux mensuels des mesures. Octobre 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  10. Monthly results of measurements: September 1998; Tableaux mensuels des mesures. Septembre 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  11. Monthly results of measurements: February 1998; Tableaux mensuels des mesures. Fevrier 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables

  12. Monthly results of measurements. Jun 1996; Tableaux mensuels des mesures. Juin 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  13. Monthly results of measurements: Dec 1999; Tableaux mensuels des mesures. Decembre 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  14. Monthly results of measurements. Mar 1999; Tableaux mensuels des mesures. Mars 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    his report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  15. Monthly results of measurements: Oct 1999; Tableaux mensuels des mesures. Octobre 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain(milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  16. Monthly results of measurements: November 1999; Tableaux mensuels des mesures. Novembre 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  17. Monthly results of measurements: Aug 1999; Tableaux mensuels des mesures. Aout 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    his report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  18. Monthly results of measurements: January 1999; Tableaux mensuels des mesures. Janvier 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  19. Monthly results of measurements: February 1999; Tableaux mensuels des mesures. Fevrier 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  20. Monthly results of measurements. Jun 1999; Tableaux mensuels des mesures. Juin 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    his report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  1. Monthly results of measurements. Apr 1999; Tableaux mensuels des mesures. Avril 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  2. Monthly results of measurements: July 1999; Tableaux mensuels des mesures. Juillet 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  3. Monthly results of measurements: Sep 1999; Tableaux mensuels des mesures. Septembre 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  4. Monthly results of measurements: Sep 1997; Tableaux mensuels des mesures. Septembre 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  5. Monthly results of measurements: May 1998; Tableaux mensuels des mesures. Mai 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  6. Monthly results of measurements: Sep 1996; Tableaux mensuels des mesures. Septembre 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  7. Monthly results of measurements: Jul 1998; Tableaux mensuels des mesures. Juillet 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  8. Monthly results of measurements: November 1997; Tableaux mensuels des mesures. Novembre 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables

  9. Monthly results of measurements: December 1997; Tableaux mensuels des mesures. Decembre 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables

  10. Monthly results of measurements: Oct 1997; Tableaux mensuels des mesures. Octobre 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  11. Monthly results of measurements: October 1994; Tableaux mensuels des mesures. Octobre 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  12. Monthly results of measurements: April 1998; Tableaux mensuels des mesures. Avril 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables

  13. Monthly results of measurements. July 1996; Tableaux mensuels des mesures. juillet 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  14. Monthly results of measurements: February 1995; Tableaux mensuels des mesures. Fevrier 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  15. Monthly results of measurements: Aug 1996; Tableaux mensuels des mesures. Aout 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  16. Monthly results of measurements: Jan 1997; Tableaux mensuels des mesures. Janvier 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  17. Monthly results of measurements: January 1995; Tableaux mensuels des mesures. Janvier 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  18. Monthly results of measurements: Jun 1997; Tableaux mensuels des mesures. Juin 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  19. Monthly results of measurements: November 1998; Tableaux mensuels des mesures. Novembre 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  20. Monthly results of measurements. April 1996; Tableaux mensuels des mesures. Avril 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  1. Monthly results of measurements: Feb 1997; Tableaux mensuels des mesures. Fevrier 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  2. Monthly results of measurements: May 1997; Tableaux mensuels des mesures. Mai 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  3. Monthly results of measurements: October 1995; Tableaux mensuels des mesures. Octobre 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  4. Monthly results of measurements: Dec 1996; Tableaux mensuels des mesures. Decembre 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  5. Monthly results of measurements: December 1995; Tableaux mensuels des mesures. Decembre 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  6. Monthly results of measurements: October 1995; Tableaux mensuels des mesures. Octobre 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  7. Monthly results of measurements: March 1996; Tableaux mensuels des mesures. Mars 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  8. Monthly results of measurements: Mars 1998; Tableaux mensuels des mesures. Mars 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables

  9. Monthly results of measurements: April 1995; Tableaux mensuels des mesures. Avril 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  10. Intravitreal bevacizumab treatment for choroidal neovascularization in pathologic myopia: 12-month results.

    Science.gov (United States)

    Gharbiya, Magda; Allievi, Francesca; Mazzeo, Luigi; Gabrieli, Corrado Balacco

    2009-01-01

    To evaluate the short-term efficacy and safety of intravitreal bevacizumab for the treatment of myopic choroidal neovascularization (CNV). Prospective, nonrandomized, interventional case series. Twenty eyes from 20 patients with CNV secondary to pathologic myopia participated in this prospective nonrandomized interventional case series. All patients were scheduled for three monthly intravitreal bevacizumab 1.25 mg injections. Early Treatment Diabetic Retinopathy Study best-corrected visual acuity (BCVA), foveal center thickness (FCT) on optical coherence tomography (OCT), and fluorescein angiographic findings were examined before and after treatment. Patients were followed up for 12 months. The mean BCVA (+/- standard deviation [SD]) at baseline was 24.8 (+/- 11.86) letters (Snellen equivalent: 20/80). At 12 months after treatment, the mean BCVA (+/- SD) improved significantly (P = .000001) to 43 (+/- 12.38) letters (Snellen equivalent: 20/35). At 12 month follow-up, BCVA improved 10 letters or more in 18 (90%) out of 20 treated eyes and improved 15 letters or more in 14 (70%) out of 20 treated eyes. No treated eyes experienced a worsening of BCVA from baseline. The mean FCT (+/- SD) at baseline was 223 (+/- 47.43) microns. At 12 months after treatment, the mean FCT (+/- SD) reduced to 206 (+/- 50.87) microns. This reduction in FCT after treatment was not statistically significant (P = .11). At 12 months follow-up, absence of fluorescein leakage from the CNV was demonstrated in 19 (95%) out of 20 treated eyes and persistent leakage in one eye (5%). None of the 19 eyes that had CNV closure experienced recurrence at 12-month follow-up. No ocular or systemic adverse effects from treatment were encountered. These results of intravitreal bevacizumab in myopic CNV are very promising with no apparent short-term safety concerns. At 12 months, treated eyes had a significant improvement in visual acuity (VA). OCT findings, as well, showed a trend consistent with the

  11. Intravitreal bevacizumab as primary treatment for retinal angiomatous proliferation: twelve-month results.

    Science.gov (United States)

    Gharbiya, Magda; Allievi, Francesca; Recupero, Vincenzo; Martini, Delia; Mazzeo, Luigi; Gabrieli, Corrado Balacco

    2009-06-01

    To evaluate the short-term efficacy and safety of intravitreal bevacizumab for the treatment of retinal angiomatous proliferation. Seventeen eyes from 16 patients with newly diagnosed retinal angiomatous proliferation underwent intravitreal injections of bevacizumab, 1.25 mg. The patients were scheduled for three monthly bevacizumab injections. Early Treatment of Diabetic Retinopathy Study (ETDRS) best-corrected visual acuity, central macular thickness on optical coherence tomography, and fluorescein angiographic findings were examined before and after treatment. Patients were followed-up for 12 months. The mean best-corrected visual acuity (+/- standard deviation [SD]) at baseline was 39.53 (+/-10.40) letters (Snellen equivalent: 20/42). At 12 months after treatment the mean best-corrected visual acuity (+/-SD) improved significantly (P = 0.0000001) to 47.88 (+/-11.78) letters (Snellen equivalent: 20/28). Best-corrected visual acuity improved 3 ETDRS lines or more in 3 (17.65%) of 17 treated eyes, 14 (82.35%) eyes were stable, and 15 (88.23%) eyes gained 1 or more ETDRS lines. The mean central macular thickness (+/-SD) at baseline was 297 (+/-60.72) microm. At 12 months after treatment, the mean central macular thickness (+/-SD) reduced significantly (P = 0.00001) to 237 (+/-28.80) microm. At the 12-month follow-up, absence of fluorescein leakage was demonstrated in 14 (82%) of 17 treated eyes. No ocular or systemic adverse effects from treatment were encountered. The 12-month results of intravitreal bevacizumab for retinal angiomatous proliferation are very promising with no apparent short-term safety concerns. Treated eyes had a significant functional and anatomical improvement. Further studies will be needed to better determine long-term efficacy and safety.

  12. Test results self-informativity properties annual dynamics of mean monthly air temperature anomalies

    Directory of Open Access Journals (Sweden)

    Nadezhda Aleksandrovna Vazhnova

    2016-11-01

    Full Text Available In this paper it is discussed the issues of methodology and the results of testing the possibilities of using the self- informatively properties in the series of the mean monthly air temperature anomalies (MMATA for the purposes of long-term forecasting of the thermal regime conditions on the example of Kazan Station, university. It is found that the prognostic informatively of the MMATA (for thermal conditions of July of the separately considered months is not statistically significant (missing since the previous June and in the earlier history, excluding the last 2 weeks of June, where the prognostic informatively is confirmed with the probability of ≥ 95%. The prognostic informatively of the mean monthly air temperature anomalies in relation to the thermal conditions of July rapidly increases with an increase in the accounted length of history of changes (preceding to the predicant in the mean monthly air temperature anomalies. It is shown that the filling of useful prognostic information takes place from April to June in relation to the conditions of Kazan. The accounting of self-informativity properties of the series of mean monthly air temperature anomalies has showed that the overall accuracy of the forecasts amounts to = 90%, at the general accuracy of random forecasts 0 = 74%, and at the methodical win = 16%. All these data suggest that the forecasts are at random level. Whereof we can conclude that the nonparametric discriminant analysis method is not always gives the positive results. Therefore, it is advisable to use more precise methods for the long-term weather forecasts, which give more acceptable forecast results with more accuracy.

  13. Efficacy of healing process of bone defects after apicectomy: results after 6 and 12 months.

    Science.gov (United States)

    Dominiak, M; Lysiak-Drwal, K; Gedrange, T; Zietek, M; Gerber, H

    2009-12-01

    The aim of this study was to assess the efficacy of selected surgical treatment techniques of bone defects after apectomy. A total of 106 postresection bone defects, located in maxilla and mandible were included in the study: the defects were treated with resorbable collagen membrane (BG I- 26 defects), xenogenic bovine material (BOC II- 30 defects) and xenogenic bovine material with platelet rich plasma (BOC/PRP III- 20 defects). In the control group the defects were left to heal spontaneously. Clinical and radiological assessment was performed at 6 and 12 months after the procedures. The analysis among groups revealed higher efficiency of the method of treatment that uses guide bone regeneration in comparison to the group in both post-operative control periods. After 6 months, the differences were statistically significant for each group using the regeneration methods, but after 12 months only for the BOC/PRP group. Treatment using selected guided bone regeneration techniques proved superior to the control group in both observation periods, but after 6 as well 12 months the best results in the BOC/PRP group were observed.

  14. Monthly results of measurements. May 1999; Tableaux mensuels des mesures. Mai 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain(milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  15. Newborn of mothers affected by autoimmune thyroiditis: the importance of thyroid function monitoring in the first months of life

    Directory of Open Access Journals (Sweden)

    Mosca Fabio

    2010-03-01

    Full Text Available Abstract Background evaluation of thyroid function in neonates born from mothers affected by autoimmune thyroiditis in order to define if a precise follow-up is necessary for these children. The influence of maternal thyroid peroxidase antibody (TPOAb and L-thyroxine therapy during pregnancy on neonatal thyroid function was also investigated. Methods 129 neonates were tested for thyroid function by measurement of free thyroxine (FT4 and thyroid stimulating hormone (TSH in 3th day, 15th day and at one month of life. TPOAb were measured in all patients; periodical control of thyroid function were performed until 6 months of life if Ab were positive. Data concerning etiology of maternal hypothyroidism and maternal replacement therapy with L-thyroxine during pregnancy were retrospectively collected. Results 28% neonates showed at least a mild increase of TSH value at the different determinations. In the majority of them, a spontaneous completely normalisation of TSH value was observed within the first month life. L-thyroxine replacement therapy was started in 3 neonates. TPOAb titer and maternal L-thyroxine replacement therapy were not related to alteration of thyroid hormone function in our study population. Conclusions transient mild elevation of serum TSH above the normal reference value for age is frequently observed in the first month of life in infants born from mothers affected by autoimmune thyroiditis. Persistent hyperthyrotropinemia requiring replacement therapy is observed in 2.2% of these neonates. According to our experience, follow-up is recommended in these newborns; the most accurate and not invasive way to carefully monitor these infants after neonatal screening for CH seems to be serum-testing TSH between 2ndand 4th week of life.

  16. Use of the gamma distribution to represent monthly rainfall in Africa for drought monitoring applications

    Science.gov (United States)

    Husak, Gregory J.; Michaelsen, Joel C.; Funk, Christopher C.

    2007-01-01

    Evaluating a range of scenarios that accurately reflect precipitation variability is critical for water resource applications. Inputs to these applications can be provided using location- and interval-specific probability distributions. These distributions make it possible to estimate the likelihood of rainfall being within a specified range. In this paper, we demonstrate the feasibility of fitting cell-by-cell probability distributions to grids of monthly interpolated, continent-wide data. Future work will then detail applications of these grids to improved satellite-remote sensing of drought and interpretations of probabilistic climate outlook forum forecasts. The gamma distribution is well suited to these applications because it is fairly familiar to African scientists, and capable of representing a variety of distribution shapes. This study tests the goodness-of-fit using the Kolmogorov–Smirnov (KS) test, and compares these results against another distribution commonly used in rainfall events, the Weibull. The gamma distribution is suitable for roughly 98% of the locations over all months. The techniques and results presented in this study provide a foundation for use of the gamma distribution to generate drivers for various rain-related models. These models are used as decision support tools for the management of water and agricultural resources as well as food reserves by providing decision makers with ways to evaluate the likelihood of various rainfall accumulations and assess different scenarios in Africa. 

  17. Results of monitoring at Olkiluoto in 2012. Environment

    Energy Technology Data Exchange (ETDEWEB)

    Haapanen, A. (ed.) [Haapanen Forest Consulting, Vanhakylae (Finland)

    2014-04-15

    In 2003, Posiva Oy presented a programme for monitoring at Olkiluoto during construction and operation of ONKALO. In 2012 the monitoring programme was updated to concern the years 2012-2018. Part of the monitoring is performed by the company running the nuclear power plants on the island, Teollisuuden Voima Oy (TVO). This Working Report presents the main results of Posiva's environmental monitoring programme on Olkiluoto Island in 2012. Results are presented under five topics: 1. Evolution of geosphere, 2. Biosphere modelling input data, 3. Interaction between surface environment and groundwater in bedrock, 4. Environmental impact and 5. Baseline of monitoring of radioactive releases. Concerning the evolution of geosphere, LIDAR-scannings were done in the Olkiluoto area in 2012. The acquired data can be used for elevation and other modelling purposes. The soil solution quality in 2012 was quite comparable to that in earlier years. Proximity of the sea and the young age of soils are seen in soil solution results. Biosphere modelling input data in 2012 included e.g. continuous tree litterfall and transpiration data, as well as updated game statistics and population estimates of fauna, a fishery survey from the River Eurajoki (2011) and basic monitoring data from Olkiluoto offshore properties. Interaction between surface environment and groundwater in bedrock includes e.g. weather and surface water monitoring data. Environmental impact analyses included e.g. monitoring of noise, air quality, effluent waters and private drilled wells. Noise monitoring in the vicinity of ONKALO showed that in the case of raised noise levels the sources are mainly the traffic on Olkiluodontie road, the air conditioning of ONKALO and occasional sources such as springtime bird sounds. Construction activities in the area were seen in increased amount of NO{sub 3}-N in the bulk deposition, and Al and Fe accumulating on needle surfaces in areas close to the rock piling and crushing area

  18. Six-Month Clinical and Angiographic Results of Paclitaxel Eluting Simpax Stent

    Directory of Open Access Journals (Sweden)

    Mehmet Muhsin Türkmen

    2012-08-01

    Full Text Available Introduction: We aimed to evaluate the safety and efficacy of the simpax stent in the treatmentof different patient groups.Patients and Methods: Forty-five patients were treated with the simpax stent. Of these patients,23 patients gave consent for six months of follow-up by quantitative coronary angiography (QSAand six patients were evaluated by exercise electrocardiographic test. Only the patients havinglesions with stenosis > 50% of diameter and lengths > 16 mm with reference diameters < 2.75mm were included.Results: The device success rate was 100% and procedure success rate was 97.7%. The meanstent length was 24.6 ± 7.3 mm and stent size was 2.54 ± 0.24 mm. The overall six months incidenceof major adverse cardiac events (MACE was 8.8%. MACE was consisted of two casesof non-Q wave myocardial infarction and two cases of repeated revascularization of the targetlesion. MACE rate was higher in chronic total occlusion (CTO group than non-CTO group (respectively33.3% and 5.1. Also when compared to stent size, MACE rate was 25% in < 2.5 mm,0% ≥ 2.5 mm. The QSA results at six months showed in-stent late lumen loss witha diameter of0.25 ± 0.15 mm in 17 patients.Conclusion: The six month results in this study demonsrated excellent procedural and devicesuccess. Simpax stent was associated with a low in-stent late lumen loss. Also this study showedsimpax stent was a safe and effective device in non-CTO group with stent size ≥ 2.5 mm.

  19. Initial commissioning results from the APS loss monitor system

    Science.gov (United States)

    Patterson, Donald R.

    1997-01-01

    The design of the beam loss monitor system for the Argonne National Laboratory Advanced Photon Source is based on using a number of air dielectric coaxial cables as long ionization chambers. Results to date show that the loss monitor is useful in helping to determine the cause of injection losses and losses large enough to limit circulating currents in the storage ring to short lifetimes. Sensitivities ranging from 13 to 240 pC of charge collected in the injector BTS (booster-to-storage-ring) loss monitor per picocoulomb of loss have been measured, depending on the loss location. These results have been used to predict that the storage ring loss monitor leakage current limit of 10 pA per cable should allow detection of losses resulting in beam lifetimes of 100 hours or less with 100 mA stored beam. Significant DC bias levels associated with the presence of stored beam have been observed. These large bias levels are most likely caused by the loss monitor responding to hard x-ray synchrotron radiation. No such response to synchrotron radiation was observed during earlier tests at SSRL. However, the loss monitor response to average stored beam current in APS has provided a reasonable alternative to the DC current transformer (DCCT) for measuring beam lifetimes.

  20. The new SLS beam size monitor, first results

    CERN Document Server

    Saa Hernandez, A; Rohrer, M; Schlott, V; Streun, A; Andersson, A; Breunlin, J

    2013-01-01

    An extremely small vertical beam size of 3.6 µm, corresponding to a vertical emittance of 0.9 pm, only about five times bigger than the quantum limit, has been achieved at the storage ring of the Swiss Light Source (SLS). The measurement was performed by means of a beam size monitor based on the imaging of the vertically polarized synchrotron radiation in the visible and UV spectral ranges. However, the resolution limit of the monitor was reached during the last measurement campaign and prevented further emittance minimization. In the context of the work package SLS Vertical Emittance Tuning of the TIARA collaboration, a new improved monitor was built. It provides larger magnification, an increase of resolution and enables two complementary methods of measurement: imaging and interferometry. In this paper we present the design, installation, commissioning, performance studies and first results obtained with the new monitor.

  1. Solvent Hold Tank Sample Results for MCU-15-556-557-558. March 2015 Monthly Sample

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Taylor-Pashow, K. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-05-04

    Savannah River National Laboratory (SRNL) received one set of Solvent Hold Tank (SHT) samples (MCU-15-556, MCU-15-557, and MCU-15-558), pulled on 03/16/2015 for analysis. The samples were combined and analyzed for composition. Analysis of the composite sample MCU-15-556-557-558 indicated a low concentration (~ 78 % of nominal) of the suppressor (TiDG) and concentrations of the extractant (MaxCalix), and of the modifier (CS-7SB) in the solvent that were slightly lower than nominal. This analysis confirms the addition of TiDG, MaxCalix, and modifier to the solvent in February 2015. Based on the current monthly sample, the levels of TiDG, MaxCalix, and modifier are sufficient for continuing operation without adding a trim at this time. No impurities above the 1000 ppm level were found in this solvent by the Semi-Volatile Organic Analysis (SVOA). However, the p-nut vials that delivered the samples contained small (1 mm) droplets of oxidized modifier and amides (as detected by the FTIR analysis). In addition, up to 21 microgram of mercury per gram of solvent (or 17.4 µg/mL) was detected in this sample. The laboratory will continue to monitor the quality of the solvent in particular for any new impurities or degradation of the solvent components.

  2. Solvent Hold Tank Sample Results For MCU-15-750-751-752-: June Monthly Sample

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Taylor-Pashow, K. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-10-07

    Savannah River National Laboratory (SRNL) received one set of Solvent Hold Tank (SHT) samples (MCU-15-750, MCU-15-751, and MCU-15-752), pulled on 06/22/2015 for analysis. The samples were combined and analyzed for composition. Analysis of the composite sample MCU-15-750-751-752 indicated a low concentration (~ 49 % of nominal) of the suppressor (TiDG) and slightly lower than nominal concentrations of the extractant (MaxCalix), and of the modifier (Cs-7SB) in the solvent. This analysis confirms the addition of TiDG, MaxCalix, and modifier to the solvent in February 2015. Based on the current monthly sample, the levels of TiDG, MaxCalix, and modifier are sufficient for continuing operation without adding a trim at this time but it is recommended that an addition of TiDG, modifier and Isopar™L should be made in the near future. No impurities above the 1000 ppm level were found in this solvent by the Semi-Volatile Organic Analysis (SVOA). No impurities were observed in the Hydrogen Nuclear Magnetic Resonance (HNMR). In addition, up to 13.9 micrograms of mercury per gram of solvent (or 11.5 µg/mL) was detected in this sample. The laboratory will continue to monitor the quality of the solvent in particular for any new impurities or degradation of the solvent components.

  3. Results of monitoring at Olkiluoto in 2009. Environment

    Energy Technology Data Exchange (ETDEWEB)

    Haapanen, A. (ed.) (Haapanen Forest Consulting, Vanhakylae (Finland))

    2010-10-15

    This Working Report presents the main results of Posiva Oy's environmental monitoring programme on Olkiluoto Island in 2009. These summary reports have been published since 2005. The environmental monitoring system supervised by Posiva Oy produces input for biosphere modelling for long-term safety purposes as well as for monitoring the state of the environment during the construction (and later operation) of ONKALO underground characterization facility. Part of the monitoring is performed by the company running the nuclear power plants on the island, Teollisuuden Voima Oy (TVO). Monitoring has been carried out for varying periods of time depending on the sector: some monitoring activities performed by TVO originate from the 1970s and the repository-related environmental monitoring of Olkiluoto from the early 2000s. The monitoring programme evolves according to the experiences gained from the modelling work and an increased understanding of the site. Augmentations in 2009 include e.g. establishment of a new forest intensive monitoring plot (FIP14), continuation of studies on fine roots and on the species composition and abundances of small mammals. Line transect samplings of ants, terrestrial snails and earthworms were carried out and a systematic monitoring of island birds was started. In addition, a project was started where the sediment load and factors affecting the sediment transportation into Eurajoensalmi bay is examined. Dust produced during construction of the third nuclear power unit (OL3), ONKALO and related infrastructure can be seen in the soil solution and deposition results. Furthermore, the construction works and road traffic have a raising effect on the noise levels of the immediate surroundings. The land-use continues to change, but the remaining natural environment resembles other coastal locations. The young age of the soils and the closeness of the sea are reflected in the soil properties. Mammalian fauna on the island is typical of coastal

  4. Chickamauga Reservoir 1992 fisheries monitoring cove rotenone results

    Energy Technology Data Exchange (ETDEWEB)

    Kerley, B.L.

    1993-06-01

    The Tennessee Valley Authority (TVA) is required by the National Pollutant Discharge Elimination System (NPDES) Permit for Sequoyah Nuclear Plant (SQN) to conduct and report annually a nonradiological operational monitoring program to evaluate potential effects of SQN on Chickamauga Reservoir. This monitoring program was initially designed to identify potential changes in water quality and biological communities in Chickamauga Reservoir resulting from operation of SQU. Chickamauga Reservoir cove rotenone sampling has also been conducted as part of the preoperational monitoring program for Watts Bar Nuclear Plant (WBN) to evaluate the combined effects of operating two nuclear facilities on one reservoir once WBU becomes operational. The purpose of this report is to present results of cove rotenone sampling conducted on Chickamauga Reservoir in 1992.

  5. Solvent Hold Tank Sample Results for MCU-15-661-662-663: April 2015 Monthly Sample

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Taylor-Pashow, K. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-07-08

    The Savannah River National Lab (SRNL) received one set of Solvent Hold Tank (SHT) samples (MCU-15-661, MCU-15-662, and MCU-15-663 pulled on April 2, 2015) for analysis. The samples were combined and analyzed for composition. Analysis of the composite sample MCU-15-661-662-663 indicated a low concentration (~ 63% of nominal) of the suppressor (TiDG) and a slightly below the nominal concentration (~ 10% below nominal) of the extractant (MaxCalix). The modifier (CS-7SB) level was also 10% below its nominal value while the Isopar™ L level was slightly above its nominal value. This analysis confirms the addition of Isopar™L to the solvent on March 6, 2015. Despite that the values are below target component levels, the current levels of TiDG, CS-7SB and MaxCalix are sufficient for continuing operation without adding a trim at this time until the next monthly sample. No impurities above the 1000 ppm level were found in this solvent. However, the sample was found to contain approximately 18.4 ug/gsolvent mercury. The gamma level increased to 8 E5 dpm/mLsolvent and it represents an order of magnitude increase relative to previous solvent samples. The increase means less cesium is being stripped from the solvent. Further analysis is needed to determine if the recent spike in the gamma measurement is due to external factors such as algae or other material that may impede stripping. The laboratory will continue to monitor the quality of the solvent in particular for any new impurity or degradation of the solvent components.

  6. Solvent hold tank sample results for MCU-16-53-55. January 2016 Monthly sample

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Jones, D. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-03-28

    Savannah River National Laboratory (SRNL) received one set of Solvent Hold Tank (SHT) samples (MCU-16-53-54-55), pulled on 01/25/2016 for analysis. The samples were combined and analyzed for composition. Analysis of the composite sample MCU-16-53-54-55 indicated the Isopar™L, and MaxCalix are at nominal levels. The modifier and TiDG concentrations are 3% and 23 % below their nominal concentrations. This analysis confirms the addition of TiDG, MaxCalix, and modifier to the solvent on November 28, 2015. Based on the current monthly sample, the levels of TiDG, Isopar™L, MaxCalix, and modifier are sufficient for continuing operation but are expected to decrease with time. Periodic characterization and trimming additions to the solvent are recommended. No impurities above the 1000 ppm level were found in this solvent by the Semi-Volatile Organic Analysis (SVOA). No impurities were observed in the Hydrogen Nuclear Magnetic Resonance (HNMR). However, the Fourier transform infra-red spectroscopy (FTIR) method detected trace levels (a few ppm) of amides (a possible degradation product of TiDG). In addition, up to 21 ± 4 micrograms of mercury per gram of solvent (or 17.5 μg/mL) was detected in this sample. There appears to be a possible correlation between the mercury level and the TiDG concentration in the solvent. The current gamma level (9.16 E4 dpm/mL) confirmed that the gamma concentration has returned to previous level where the process operated normally and as expected. The laboratory will continue to monitor the quality of the solvent in particular for any new impurities or degradation of the solvent components.

  7. Solvent hold tank sample results for MCU-15-914-915-916. December 2015 Monthly sample

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Jones, D. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-03-01

    Savannah River National Laboratory (SRNL) received one set of Solvent Hold Tank (SHT) samples (MCU-15-914-915-916), pulled on 12/22/2015 for analysis. The samples were combined and analyzed for composition. Analysis of the composite sample MCU-15-914-915-916 indicated the TiDG, Isopar™L, and MaxCalix are at nominal levels. The modifier concentration is 3% below its nominal concentration. This analysis confirms the addition of TiDG, MaxCalix, and modifier to the solvent in November 2015. Based on the current monthly sample, the levels of TiDG, Isopar™L, MaxCalix, and modifier are sufficient for continuing operation but are expected to decrease with time. Periodic characterization and trimming additions to the solvent are recommended. No impurities above the 1000 ppm level were found in this solvent by the Semi-Volatile Organic Analysis (SVOA). No impurities were observed in the Hydrogen Nuclear Magnetic Resonance (HNMR). However, the Fourier transform infra-red spectroscopy (FTIR) method detected trace levels (a few ppm) of amides (more indicative of bacteria than a possible degradation product of TiDG). In addition, up to 18 ± 4 micrograms of mercury per gram of solvent (or 14.8 μg/mL) was detected in this sample. The current gamma concentration level (8.48E4 dpm/mL) confirmed that the gamma concentration has returned to the previous level where the process operated normally as expected. The laboratory will continue to monitor the quality of the solvent in particular for any new impurities or degradation of the solvent components.

  8. Solvent Hold Tank Sample Results For MCU-15-710-711-712: June 2015 Monthly Sample

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Taylor-Pashow, K. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-10-07

    Savannah River National Laboratory (SRNL) received one set of Solvent Hold Tank (SHT) samples (MCU-15-710, MCU-15-711, and MCU-15-712), pulled on 06/15/2015 for analysis. The samples were combined and analyzed for composition. Analysis of the composite sample MCU-15-710-711-712 indicated a low concentration (~ 55 % of nominal) of the suppressor (TiDG) and concentrations of the extractant (MaxCalix), and of the modifier (Cs-7SB) in the solvent that were slightly lower than nominal. This analysis confirms the addition of TiDG, MaxCalix, and modifier (92 % of nominal) to the solvent in February 2015. Based on the current monthly sample, the levels of TiDG, MaxCalix, and modifier were sufficient when this solvent sample was collected from MCU. A higher cesium concentration (9.3 E6 dpm/mL) was observed in this sample relative to recent samples. In the past, this level of cesium appeared to correlate with upsets in the MCU operation. It is not known at this time the reason for the higher cesium level in this solvent. No impurities above the 1000 ppm level were found in this solvent by the Semi-Volatile Organic Analysis (SVOA). In addition, the sample contains up to 10.4 micrograms of mercury per gram of solvent (or 8.7 µg/mL). A relatively large cesium concentration (9.3 E 6 dpm/mL) was measured in this solvent and it may indicate poor cesium stripping. The laboratory will continue to monitor the quality of the solvent in particular for any new impurities or degradation of the solvent components.

  9. Traffic monitoring using handheld GSM phones. Part B: Simulation results

    NARCIS (Netherlands)

    Catalano, S.; Lindveld, C.; Van der Zijpp, N.

    2001-01-01

    Report published by the the University of Technology Delft, commissioned by Syntrack. This report contains the description of a novel map-matching algorithm, and the results of a simulation study into the feasibility of traffic monitoring using handheld mobile phones.

  10. Hanford coring bit temperature monitor development testing results report

    Energy Technology Data Exchange (ETDEWEB)

    Rey, D.

    1995-05-01

    Instrumentation which directly monitors the temperature of a coring bit used to retrieve core samples of high level nuclear waste stored in tanks at Hanford was developed at Sandia National Laboratories. Monitoring the temperature of the coring bit is desired to enhance the safety of the coring operations. A unique application of mature technologies was used to accomplish the measurement. This report documents the results of development testing performed at Sandia to assure the instrumentation will withstand the severe environments present in the waste tanks.

  11. Measurement results obtained from air quality monitoring system

    Energy Technology Data Exchange (ETDEWEB)

    Turzanski, P.K.; Beres, R. [Provincial Inspection of Environmental Protection, Cracow (Poland)

    1995-12-31

    An automatic system of air pollution monitoring operates in Cracow since 1991. The organization, assembling and start-up of the network is a result of joint efforts of the US Environmental Protection Agency and the Cracow environmental protection service. At present the automatic monitoring network is operated by the Provincial Inspection of Environmental Protection. There are in total seven stationary stations situated in Cracow to measure air pollution. These stations are supported continuously by one semi-mobile (transportable) station. It allows to modify periodically the area under investigation and therefore the 3-dimensional picture of creation and distribution of air pollutants within Cracow area could be more intelligible.

  12. Results of Monitoring at Olkiluoto in 2010. Rock Mechanics

    Energy Technology Data Exchange (ETDEWEB)

    Lahti, M. (ed.); Siren, T.

    2011-12-15

    The rock mechanical monitoring at Olkiluoto concentrates on the assessment of potential tectonic movements and stability of the bedrock. The construction of ONKALO is not expected to induce large-scale movements of the rock blocks or affect the rate of isostatic uplift but the evaluation of any tectonic events is important for the safety assessment. The monitoring consists of seismic measurements, GPS measurements and precise levelling campaigns at Olkiluoto and vicinity and extensometer and convergence measurements carried out in ONKALO. Posiva established a local seismic network of six stations on the island of Olkiluoto in 2002. After that the number of seismic stations has increased gradually. In 2010 the permanent seismic network consists of 15 seismic stations and 20 triaxial sensors. The purpose of the microearthquake measurements at Olkiluoto is to improve understanding of the structure, behaviour and long term stability of the bedrock. The investigation area includes two target areas. The larger target area, called seismic semiregional area, covers the Olkiluoto Island and its surroundings. The purpose is to monitor explosions and tectonic earthquakes in regional scale inside that area. The smaller target area is called the seismic ONKALO block, which is a 2 km *2 km *2 km cube surrounding the ONKALO. It is assumed that all the expected excavation induced events occur within this volume. At the moment the seismic ONKALO block includes ten seismic stations. An additional task of monitoring is related to safeguarding of the ONKALO. This report gives the results of microseismic monitoring during 2010.

  13. Comprehensive rehabilitation of patients with early rheumatoid arthritis: results of 6-month program

    Directory of Open Access Journals (Sweden)

    Evgenia Vladislavovna Orlova

    2013-01-01

    Full Text Available Objective: to evaluate the efficiency of a comprehensive rehabilitation program (CRP in patients with early rheumatoid arthritis (RA for 6 months. Subjects and methods. Sixty patients with early RA were examined. During medical therapy, 6-month CRP was implemented in 34 patients in the study group. The 2-week in-hospital stage involved ten sessions of 15-min local air cryotherapy (-60 °C of the hands, knee or ankle joints; ten classes of 45-min therapeutic exercises (TE under the supervision of a trainer; ten sessions of 45-min ergotherapy (training people how to therapeutically position their joints, to apply their protective methods, to lift and move things, to use assistive devices, and to do hand exercises; orthotics (working wrist orthoses, knee ones, or individual orthopedic insoles; and four 90-min educational program classes. The outpatient and domiciliary stages included 45-min TE thrice weekly; creation of a correct functional stereotype; and orthotics. Twenty-six patients received medical therapy only (a control group. The authors estimated tender joint count (TJC, swollen joint count (SJC, erythrocyte sedimentation rate (ESR, C-reactive protein (CRP, joint pain on 100-mm visual analog scale (VAS, DAS28, HAQ, RAPID3, hand grip strength, average maximum knee extension and ankle flexion by the EN-TreeM movement analysis, and compliance with drug and non-drug treatments. Results. The study group showed a stably high compliance with therapy with disease-modifying antirheumatic drugs, less need for symptomatic agents, higher adherence to the methods of creating a correct functional stereotype, orthotics, and regular TE. Twenty-two patients completed 6-month CRP; 12 patents did not complete the treatment because of non-compliance with nondrug methods, primarily TE. Upon completion of the in-hospital stage of CRP, the study group exhibited significant positive changes in pain and functional status and no significant impact on global

  14. Results of Monitoring at Olkiluoto in 2011. Environment

    Energy Technology Data Exchange (ETDEWEB)

    Haapanen, A. (ed.) [Haapanen Forest Consulting, Vanhakylae (Finland)

    2012-11-15

    This Working Report presents the main results of Posiva Oy's environmental monitoring programme on Olkiluoto Island in 2011. These summary reports have been published since 2005. The environmental monitoring system supervised by Posiva Oy produces input for biosphere modelling for long-term safety purposes as well as for monitoring the state of the environment during the construction (and later operation) of ONKALO underground rock characterization facility. Part of the monitoring is performed by the company running the nuclear power plants on the island, Teollisuuden Voima Oy (TVO). Monitoring has been carried out for varying periods of time depending on the sector: some monitoring activities performed by TVO originate from the 1970s and the repository-related environmental monitoring of Olkiluoto from the early 2000s. The monitoring programme evolves according to experiences gained from the modelling work and increased understanding of the site. Monitoring activities in 2011 proceeded according to the plans. The land-use of the island continues to change due to the construction work of OL3, ONKALO and related infrastructure, but the remaining natural environment resembles other coastal locations. The amount of nitrogen in the bulk deposition increased in 2011, whereas that of sulphur decreased. Some litterfall fractions showed higher Al and Fe values than earlier, likely caused by soil dust. Proximity of the sea is seen in wet deposition and soil solution results. Soil solution also reflects the young age of soils. Undestorey vegetation has shown no essential changes during the monitoring period. Mammalian fauna on the island is typical of coastal areas in Southwestern Finland. Game catches vary according to hunting pressure and natural variation in populations. The condition of the nearby sea is affected by the continuous land uplift, the shallowness of the area, the weather conditions, the general condition of the Bothnian Sea, the nutrient and sediment

  15. Mapping and monitoring of ablative thermal therapy for improved results

    Science.gov (United States)

    Gustafson, David E.; Nadadur, Desikachari; Dalmadge, Gary W.; Nields, Morgan

    2007-02-01

    We demonstrate a method which incorporates state-of-the-art x-ray imaging with novel thermal therapy monitoring to enable improved minimally invasive thermal-therapy delivery for benign or malignant tumors. Thermal ablative techniques including RFA, microwave, and laser ablation are gaining acceptance. Incomplete treatments are common since there is no reliable method to monitor treatment zones during ablation. Treatment that doesn't encompass the entire tumor results in recurrence usually within one year. We describe a method to monitor tumor ablation zones during ablations performed under CT image guidance. This method allows the operator to predict necrosis while avoiding injury to critical structures. We validated the model using tissue and animal experiments. We also report on initial clinical results from patients receiving RFA treatments for primary or metastatic lesions. Following CT image-guidance to position RFA devices in a patient's tumor, intraprocedural CT data was acquired and processed offline. In this paper we describe the methods to monitor and provide feedback on the ablation during the study. By demonstrating the creation of accurate thermal maps in tissue and animal models, and extending this in preliminary treatment of tumors in patients, we hope to encourage the broader adoption of these methods by improving both safety and efficacy.

  16. An eight month test campaign of the Qinetiq ZephIR system. Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Kindler, D. [Windtest Kaiser-Wilhelm-Koog GmbH (Germany); Oldroyd, A. [Oldbaum Services Ltd, Callander (United Kingdom); MacAskill, A. [Talisman Energy Ltd, Aberdeen (United Kingdom); Finch, D. [Scottish and Southern Energy Ltd, Perth (United Kingdom)

    2007-10-15

    The Beatrice Windfarm Demonstrator project is a major part of the European Union sponsored DOWNVInD programme (Distant Offshore Wind farms with No Visual Impact iN Demonstrator) that will install two multi megawatt wind turbines (of type REpower 5M) in the Moray Firth Scotland, adjacent to the Beatrice Alpha oil platform, owned and operated by Talisman Energy. As part of the project, a programme has been designed and instigated over the last eight months to thoroughly examine the performance and capabilities of the QinetiQ ZephIR LiDAR system as well as to establish its suitability for being the primary wind data acquisition instrument on the Beatrice project. This paper represents a first look at the results of this programme. (orig.)

  17. Global Monthly CO2 Flux Inversion Based on Results of Terrestrial Ecosystem Modeling

    Science.gov (United States)

    Deng, F.; Chen, J.; Peters, W.; Krol, M.

    2008-12-01

    Most of our understanding of the sources and sinks of atmospheric CO2 has come from inverse studies of atmospheric CO2 concentration measurements. However, the number of currently available observation stations and our ability to simulate the diurnal planetary boundary layer evolution over continental regions essentially limit the number of regions that can be reliably inverted globally, especially over continental areas. In order to overcome these restrictions, a nested inverse modeling system was developed based on the Bayesian principle for estimating carbon fluxes of 30 regions in North America and 20 regions for the rest of the globe. Inverse modeling was conducted in monthly steps using CO2 concentration measurements of 5 years (2000 - 2005) with the following two models: (a) An atmospheric transport model (TM5) is used to generate the transport matrix where the diurnal variation n of atmospheric CO2 concentration is considered to enhance the use of the afternoon-hour average CO2 concentration measurements over the continental sites. (b) A process-based terrestrial ecosystem model (BEPS) is used to produce hourly step carbon fluxes, which could minimize the limitation due to our inability to solve the inverse problem in a high resolution, as the background of our inversion. We will present our recent results achieved through a combination of the bottom-up modeling with BEPS and the top-down modeling based on TM5 driven by offline meteorological fields generated by the European Centre for Medium Range Weather Forecast (ECMFW).

  18. Geodetic Volcano Monitoring Research in Canary Islands: Recent Results

    Science.gov (United States)

    Fernandez, J.; Gonzalez, P. J.; Arjona, A.; Camacho, A. G.; Prieto, J. F.; Seco, A.; Tizzani, P.; Manzo, M. R.; Lanari, R.; Blanco, P.; Mallorqui, J. J.

    2009-05-01

    The Canarian Archipelago is an oceanic island volcanic chain with a long-standing history of volcanic activity (> 40 Ma). It is located off the NW coast of the African continent, lying over a transitional crust of the Atlantic African passive margin. At least 12 eruptions have been occurred on the islands of Lanzarote, Tenerife and La Palma in the last 500 years. Volcanism manifest predominantly as basaltic strombolian monogenetic activity (whole archipelago) and central felsic volcanism (active only in Tenerife Island). We concentrate our studies in the two most active islands, Tenerife and La Palma. In these islands, we tested different methodologies of geodetic monitoring systems. We use a combination of ground- and space-based techniques. At Tenerife Island, a differential interferometric study was performed to detect areas of deformation. DInSAR detected two clear areas of deformation, using this results a survey-based GPS network was designed and optimized to control those deformations and the rest of the island. Finally, using SBAS DInSAR results weak spatial long- wavelength subsidence signals has been detected. At La Palma, the first DInSAR analysis have not shown any clear deformation, so a first time series analysis was performed detecting a clear subsidence signal at Teneguia volcano, as for Tenerife a GPS network was designed and optimized taking into account stable and deforming areas. After several years of activities, geodetic results served to study ground deformations caused by a wide variety of sources, such as changes in groundwater levels, volcanic activity, volcano-tectonics, gravitational loading, etc. These results proof that a combination of ground-based and space-based techniques is suitable tool for geodetic volcano monitoring in Canary Islands. Finally, we would like to strength that those results could have serious implications on the continuous geodetic monitoring system design and implementation for the Canary Islands which is under

  19. Reduction of atrial fibrillation in remotely monitored pacemaker patients: results from a Chinese multicentre registry

    Institute of Scientific and Technical Information of China (English)

    CHEN Ke-ping; DAI Yan; HUA Wei; YANG Jie-fu; LI Kang; LIANG Zhao-guang; SHEN Fa-rong

    2013-01-01

    Background Many recipients of implantable cardiac electronic devices have atrial fibrillation (AF) occurrences after device implantation,even if there is no previous history of AF,and some of the episodes are asymptomatic.The purpose of this study was to evaluate trends in AF burden following early AF detection in patients treated with pacemakers equipped with automatic,daily Home Monitoring function.Methods Between February 2009 and December 2010,the registry recruited 701 pacemaker patients (628 dual-chamber,73 biventricular devices) at 97 clinical centers in China.Daily Home Monitoring data transmissions were analyzed to screen for the AF burden.In-office follow-ups were scheduled for 3 and 6 months after implantation.Upon first AF (i.e.,mode-switch) detection in a patient,screening of AF burden by Home Monitoring was extended for the next 180 days.Results At least one episode of AF was observed in 22.9% of patients with dual-chamber pacemakers and in 28.8% of patients with biventricular pacemakers.The first AF detection in a patient occurred,on average,about 2 months before scheduled follow-up visits.In both pacemaker groups,mean AF burden decreased significantly (P<0.05) over 180 days following first AF detection:from 12.0% to 2.5% in dual-chamber and from 12.2% to 0.5% in biventricular pacemaker recipients.The number of patients with an AF burden >10% per month was significantly reduced over 6 months of implantation in both dual chamber (38 patients in the first month vs.21 patients in month 6,P<0.05) and biventricular (7 patients in the first month vs.0 patient in months 4-6,P<0.05) pacemaker recipients.Conclusions Automatic,daily Home Monitoring of patients treated with cardiac pacemakers allows early detection of AF,and there is a gradual and significant decrease in AF burden.

  20. Cognitive Enhancement Therapy in substance misusing schizophrenia: results of an 18-month feasibility trial.

    Science.gov (United States)

    Eack, Shaun M; Hogarty, Susan S; Greenwald, Deborah P; Litschge, Maralee Y; McKnight, Summer A F; Bangalore, Srihari S; Pogue-Geile, Michael F; Keshavan, Matcheri S; Cornelius, Jack R

    2015-02-01

    Substance use is a frequent problem in schizophrenia, and although many substance misusing patients with the disorder also experience considerable cognitive impairments, such individuals have been routinely excluded from clinical trials of cognitive remediation that could support their functional and addiction recoveries. This study conducted a small-scale feasibility trial of Cognitive Enhancement Therapy (CET) in substance misusing schizophrenia patients to assess the feasibility and efficacy of implementing comprehensive neurocognitive and social-cognitive remediation in this population. A total of 31 schizophrenia outpatients meeting addiction severity criteria for alcohol and/or cannabis use were randomized to 18months of CET or usual care. Feasibility findings indicated high degrees of satisfaction with CET, but also presented significant challenges in the recruitment and retention of substance misusing patients, with high levels of attrition (50%) over the study period, primarily due to positive symptom exacerbation. Intent-to-treat efficacy analyses showed large and significant improvements in neurocognition (d=.86), social cognition (d=1.13), and social adjustment (d=.92) favoring CET. Further, individuals treated with CET were more likely to reduce alcohol use (67% in CET vs. 25% in usual care) during treatment (p=.021). These results suggest that once engaged and stabilized, CET is a feasible and potentially effective treatment for cognitive impairments in patients with schizophrenia who misuse alcohol and/or cannabis. Substance misusing patients who are able to engage in treatment may be able to benefit from cognitive remediation, and the treatment of cognitive impairments may help improve substance use outcomes among this underserved population.

  1. Women’s perceptions about reducing the frequency of monthly bleeding: results from a multinational survey

    Directory of Open Access Journals (Sweden)

    Szarewski A

    2013-05-01

    Full Text Available Anne Szarewski,1 Cecilia Moeller2 1Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, United Kingdom; 2Bayer HealthCare Pharmaceuticals, Global Market Research General Medicine, Berlin, Germany Background: Monthly bleeding can have a negative impact on daily life and, given the choice, many women would reduce the frequency of bleeding. While some women choose to occasionally postpone or reduce bleeding frequency with an oral contraceptive (OC, most women have no or limited experience of regularly reducing the frequency of scheduled bleeding with OCs, ie, the extended OC regimen. Study design: An online survey of 4039 women aged 15–49 years who were currently using, had used, or would consider using any form of hormonal contraception was conducted in Brazil, Canada, Czech Republic, France, Germany, Italy, UK, and USA to assess awareness of and the reasons for and against reducing bleeding frequency. Results: Overall, 51.1% and 30.7% of women surveyed were aware that they could occasionally or regularly reduce bleeding frequency with an OC. Moreover, 27.6% and 9.9% of previous/current OC users had occasionally or regularly reduced bleeding frequency with an OC. The main reasons for reducing bleeding frequency were convenience, physician recommendations, special events, and relief of problems associated with bleeding. Many women mistakenly believed that reducing bleeding frequency would have a negative health impact. Conclusion: Additional efforts are needed to educate women about the possibility and potential health benefits of reducing bleeding frequency and to dispel misconceptions about the use of extended OC regimens. Keywords: extended regimen, menstruation, oral contraceptive, withdrawal bleeding, scheduled bleeding

  2. Results of monitoring at Olkiluoto in 2013. Hydrology and hydrogeology

    Energy Technology Data Exchange (ETDEWEB)

    Vaittinen, T.; Ahokas, H.; Komulainen, J.; Nummela, J.; Pentti, E.; Turku, J. [Poeyry Finland Oy, Vantaa (Finland); Karvonen, T. [WaterHope, Helsinki (Finland); Aro, S.

    2014-12-15

    The impact of the construction of ONKALO is monitored by measuring and observing numerous different parameters related to hydrology, geochemistry, environment, rock mechanics and foreign materials. The Hydrological Monitoring Programme consists of the following parameters: groundwater level, hydraulic head, flow conditions in open drillholes, transverse flow, hydraulic conductivity, groundwater salinity (in situ EC), precipitation (including snow), sea-water level, surface flow (runoff), infiltration, ground frost, leakages in tunnels, and water balance in the tunnel system and in Korvensuo Reservoir. This Report focuses on hydrogeological parameters. Other parameters, like precipitation, ground frost etc. will be reported in the Monitoring Report of Environment. Updated monitoring program was introduced in the beginning of 2012. The updated program will be used for the period before repository operation. Only minor changes were implemented. Monitoring has been carried out according to plan. This Report presents the results for the year 2013. Excavation of the access tunnel was completed in 2012. Demonstration tunnels 3 and 4 were excavated and central tunnel 1 was continued from chainage 4366-22 m to chainage 4366-60 m in 2013. Total inflow into ONKALO down to chainage 4580 m including shaft ONK-KU2 down to level -437 m was on average 35 l/min in 2013. The mapping of water leakages and moisture conditions on the tunnel walls and the ceiling has been continued. The general pattern of leakages has remained similar during the construction of ONKALO. Most significant differences are caused by seasonal effects like condensation of warm ventilation air on tunnel walls and ceiling. The changes observed in the groundwater level in observation tubes in the overburden and in shallow drillholes in the bedrock are not necessarily caused by the construction of ONKALO. However, weak indications of a local decrease in groundwater level have been observed. Effects on the head

  3. Monitoring of Sound and Carious Surfaces under Sealants over 44 Months

    Science.gov (United States)

    Fontana, M.; Platt, J.A.; Eckert, G.J.; González-Cabezas, C.; Yoder, K.; Zero, D.T.; Ando, M.; Soto-Rojas, A.E.; Peters, M.C.

    2014-01-01

    Although there is strong evidence for the effectiveness of sealants, one major barrier in sealant utilization is the concern of sealing over active caries lesions. This study evaluated detection and monitoring of caries lesions through a clear sealant over 44 mo. Sixty-four 7- to 10-year-old children with at least 2 permanent molars with International Caries Detection and Assessment System (ICDAS) scores 0-4 (and caries less than halfway through the dentin, radiographically) were examined with ICDAS, DIAGNOdent, and quantitative light-induced fluorescence (QLF) before sealant placement and 1, 12, 24, and 44 mo (except QLF) after. Bitewing radiographs were taken yearly. DIAGNOdent and QLF were able to distinguish between baseline ICDAS before and after sealant placement. There was no significant evidence of ICDAS progression at 12 mo, but there was small evidence of minor increases at 24 and 44 mo (14% and 14%, respectively) with only 2% ICDAS ≥ 5. Additionally, there was little evidence of radiographic progression (at 12 mo = 1%, 24 mo = 3%, and 44 mo = 9%). Sealant retention rates were excellent at 12 mo = 89%, 24 mo = 78%, and 44 mo = 70%. The small risk of sealant repair increased significantly as baseline ICDAS, DIAGNOdent, and QLF values increased. However, regardless of lesion severity, sealants were 100% effective at 12 mo and 98% effective over 44 mo in managing occlusal surfaces at ICDAS 0-4 (i.e., only 4 of 228 teeth progressed to ICDAS ≥ 5 associated with sealants in need of repair and none to halfway or more through the dentin, radiographically). This study suggests that occlusal surfaces without frank cavitation (ICDAS 0-4) that are sealed with a clear sealant can be monitored with ICDAS, QLF, or DIAGNOdent, which may aid in predicting the need for sealant repair. PMID:25248613

  4. Monitoring of sound and carious surfaces under sealants over 44 months.

    Science.gov (United States)

    Fontana, M; Platt, J A; Eckert, G J; González-Cabezas, C; Yoder, K; Zero, D T; Ando, M; Soto-Rojas, A E; Peters, M C

    2014-11-01

    Although there is strong evidence for the effectiveness of sealants, one major barrier in sealant utilization is the concern of sealing over active caries lesions. This study evaluated detection and monitoring of caries lesions through a clear sealant over 44 mo. Sixty-four 7- to 10-year-old children with at least 2 permanent molars with International Caries Detection and Assessment System (ICDAS) scores 0-4 (and caries less than halfway through the dentin, radiographically) were examined with ICDAS, DIAGNOdent, and quantitative light-induced fluorescence (QLF) before sealant placement and 1, 12, 24, and 44 mo (except QLF) after. Bitewing radiographs were taken yearly. DIAGNOdent and QLF were able to distinguish between baseline ICDAS before and after sealant placement. There was no significant evidence of ICDAS progression at 12 mo, but there was small evidence of minor increases at 24 and 44 mo (14% and 14%, respectively) with only 2% ICDAS ≥ 5. Additionally, there was little evidence of radiographic progression (at 12 mo = 1%, 24 mo = 3%, and 44 mo = 9%). Sealant retention rates were excellent at 12 mo = 89%, 24 mo = 78%, and 44 mo = 70%. The small risk of sealant repair increased significantly as baseline ICDAS, DIAGNOdent, and QLF values increased. However, regardless of lesion severity, sealants were 100% effective at 12 mo and 98% effective over 44 mo in managing occlusal surfaces at ICDAS 0-4 (i.e., only 4 of 228 teeth progressed to ICDAS ≥ 5 associated with sealants in need of repair and none to halfway or more through the dentin, radiographically). This study suggests that occlusal surfaces without frank cavitation (ICDAS 0-4) that are sealed with a clear sealant can be monitored with ICDAS, QLF, or DIAGNOdent, which may aid in predicting the need for sealant repair.

  5. Results of monitoring at Olkiluoto in 2010. Hydrology

    Energy Technology Data Exchange (ETDEWEB)

    Vaittinen, T.; Ahokas, H.; Klockars, J.; Nummela, J.; Pentti, E.; Penttinen, T.; Poellaenen, J. [Poeyry Finland Oy, Espoo (Finland); Karvonen, T. [WaterHope, Helsinki (Finland); Lindgren, S.

    2012-03-15

    The impact of the construction of ONKALO is monitored by measuring and observing numerous different parameters related to hydrology, geochemistry, environment, rock mechanics and foreign materials. The Hydrological Monitoring Programme consists of the following parameters: groundwater level, hydraulic head, flow conditions in open boreholes, cross drillhole flow, hydraulic conductivity, groundwater salinity (in situ EC), precipitation (including snow), sea-water level, surface flow (runoff), infiltration, ground frost, leakages in tunnels, and water balance in the tunnel system and in Korvensuo Reservoir. This Report focuses on hydrogeological parameters. Other parameters, like precipitation, ground frost etc. will be reported in the Monitoring Report of Environment. Monitoring has primarily been carried out according to plan. This Report presents the results for the year 2010. A significant change took place in the Monitoring Programme when most of the open drillholes were packed-off before the excavation of the ONKALO access tunnel through the hydrogeological HZ20 zones began in June 2008. Prior to packing-off, open drillholes connected the main hydrogeological features, the HZ19 and HZ20 systems, to each other. Due to the packing-off of open drillholes, the number of flow logging and hydraulic testing (HTU) measurements has decreased considerably. The mapping of water leakages and moisture conditions in tunnel walls and roof has been continued. Some changes have been observed in the pattern of moisture content. The changes have probably been caused by shotcreting, postgrouting and possibly also by seasonal effects. The changes have so far not been analysed. The changes observed in the groundwater level in shallow observation tubes in the overburden and in shallow drillholes in the bedrock are not necessarily caused by the construction of ONKALO. However, weak indications of a decrease in groundwater level have been observed. Effects on the head deeper in the

  6. New perspective for third generation percutaneous vertebral augmentation procedures: Preliminary results at 12 months

    Directory of Open Access Journals (Sweden)

    Daniele Vanni

    2012-01-01

    Full Text Available Introduction: The prevalence of osteoporotic vertebral fractures (OVF increased in the last years. Compression fractures promote a progressive spine kyphosis increase, resulting in a weight shift and anterior column overload, with OVF additional risk (domino effect. The aim of this study is to evaluate the OVF treatment outcome using Spine Jack ®, a titanium device for third generation percutaneous vertebral augmentation procedures (PVAPs. Materials and Methods: From February 2010, a prospective randomized study was performed examining 300 patients who underwent PVAP due to OVF type A1 according to Magerl/AO spine classification. Patients enrolled in the study were divided in two homogenous groups with regards to age (65-85 years, sex, and general clinical findings. Group A included 150 patients who underwent PVAP using Spine Jack ® system; the second, group B (control group, included 150 patients treated by conventional balloon kyphoplasty. Patients underwent a clinical (visual analogue scale and Oswestry disability index and radiographic follow-up, with post-operative standing plain radiogram of the spine at 1, 6, and 12 months. The radiographic parameters that were taken into account were: Post-operative anterior vertebral body height, pre-operative anterior vertebral body height, cephalic anterior vertebral body height, and caudal anterior vertebral body height. Results: Compared to the Spine Jack ® group, the kyphoplasty group required a little longer operation time (an average of 40 min-group A vs. 45 min-group B, P < 0.05 and a greater amount of polymethylmethacrylate (4.0 mL-group A vs. 5.0 mL-group B, P < 0.05;. The post-operative increase in vertebral body height was greater in the Spine Jack ® group than in the kyphoplasty group (P < 0.05. Discussion: PVAP are based on the cement injection into the vertebral body. Vertebroplasty does not allow the vertebral body height recovery. Balloon kyphoplasty allows a temporary height

  7. Preventing compulsory admission to psychiatric inpatient care: Perceived coercion, empowerment and self-reported mental health functioning after 12 months of preventive monitoring

    Directory of Open Access Journals (Sweden)

    Barbara eLay

    2015-11-01

    Full Text Available Objective: To evaluate effects of a preventive monitoring program targeted to reduce compulsory re-hospitalization and perceived coercion in patients with severe mental disorder. We analyze patient outcomes in terms of perceived coercion, empowerment and self-reported mental health functioning at 12 months. Methods: The program consists of individualized psycho-education, crisis cards and, after discharge from the psychiatric hospital, a 24-month preventive monitoring. In total, 238 psychiatric inpatients who had had compulsory admission(s during the past 24 months were included in the trial. T1-assessment 12 months after baseline was achieved for 182 patients. Results: Study participants reported lower levels of perceived coercion, negative pressures and process exclusion, a higher level of optimism, and a lesser degree of distress due to symptoms, interpersonal relations and social role functioning (significant time effects. However, improvements were not confined to the intervention group, but seen also in the TAU group (no significant group or interaction effects. Altered perceptions were linked to older age, shorter illness duration, female sex, non-psychotic disorder, and compulsory hospitalization not due to risk of harm to others. Conclusion: Our findings suggest that changes in the subjective perspective were fuelled primarily by participation in this study, rather than by having received the specific intervention. The study contributes to a better understanding of the interaction between 'objective' measures (compulsory readmissions and patients’ perceptions and highlights the need for treatment approaches promoting empowerment in individuals with a history of involuntary psychiatric hospitalizations.

  8. Mississippi Communities for Healthy Living: Results of a 6-month nutrition education comparative effectiveness trial

    Science.gov (United States)

    The United States Lower Mississippi Delta (LMD) region suffers from high prevalence of chronic health conditions with nutritional etiologies, including obesity, high cholesterol, hypertension, and diabetes. Responding to the need for effective nutrition interventions in the LMD, a 2-arm, 6-month, n...

  9. Cognitive Enhancement Therapy for Adults with Autism Spectrum Disorder: Results of an 18-Month Feasibility Study

    Science.gov (United States)

    Eack, Shaun M.; Greenwald, Deborah P.; Hogarty, Susan S.; Bahorik, Amber L.; Litschge, Maralee Y.; Mazefsky, Carla A.; Minshew, Nancy J.

    2013-01-01

    Adults with autism experience significant impairments in social and non-social information processing for which few treatments have been developed. This study conducted an 18-month uncontrolled trial of Cognitive Enhancement Therapy (CET), a comprehensive cognitive rehabilitation intervention, in 14 verbal adults with autism spectrum disorder to…

  10. Cognitive Enhancement Therapy for Adults with Autism Spectrum Disorder: Results of an 18-Month Feasibility Study

    Science.gov (United States)

    Eack, Shaun M.; Greenwald, Deborah P.; Hogarty, Susan S.; Bahorik, Amber L.; Litschge, Maralee Y.; Mazefsky, Carla A.; Minshew, Nancy J.

    2013-01-01

    Adults with autism experience significant impairments in social and non-social information processing for which few treatments have been developed. This study conducted an 18-month uncontrolled trial of Cognitive Enhancement Therapy (CET), a comprehensive cognitive rehabilitation intervention, in 14 verbal adults with autism spectrum disorder to…

  11. Beclomethasone Dipropionate Nasal Aerosol in Patients with Perennial Allergic Rhinitis (BALANCE) study: 6-month results.

    Science.gov (United States)

    Bukstein, Donald; Parikh, Ruchir; Eid, Sherrine; Ferro, Thomas; Morello, Jean-Pierre

    2016-01-01

    Perennial allergic rhinitis (PAR) exerts significant quality-of-life and economic burdens on society. Beclomethasone dipropionate (BDP) nasal aerosol is the first nonaqueous, hydrofluoroalkane-propelled intranasal corticosteroid approved for patients in the United States to treat PAR and seasonal allergic rhinitis. To evaluate real-world effectiveness of BDP nasal aerosol from the patient's perspective by using a postmarketing observational registry. Patients (N = 824) from 43 U.S. study sites completed monthly patient-reported outcome instruments, including the Rhinitis Control Assessment Test (primary outcome variable), Treatment Satisfaction Questionnaire for Medication, Work Productivity and Activity Impairment Questionnaire plus Classroom Impairment Questions: Allergy-Specific, Pittsburgh Sleep Quality Index, and Mini Rhinoconjunctivitis Quality of Life Questionnaire for 6 months. The primary outcome assessment (Rhinitis Control Assessment Test score) (N = 527) indicated significant symptomatic improvement over baseline beginning at month 1 (p 78.8% of respondents who achieved clinically meaningful improvement over 6 months. Secondary outcome measures Mini Rhinoconjunctivitis Quality of Life Questionnaire (p Questionnaire for Medication-9 scales of effectiveness (p Work Productivity and Activity Impairment Questionnaire plus Classroom Impairment Questions: Allergy-Specific, with the exception of work time missed and class time missed, were significantly (p life, work, and school-related activities, and is associated with high patient satisfaction, reduced productivity loss and activity impairment, and improvement in sleep quality.

  12. Results of the Sherbrooke-Lac Mégantic fluoride varnish study after 20 months.

    Science.gov (United States)

    Clark, D C; Stamm, J W; Quee, T C; Robert, G

    1985-04-01

    The purpose of this study was to demonstrate the effectiveness of two fluoride varnishes (Duraphat and Fluor Protector) in the prevention of dental caries in children residing in a non-fluoridated community. At baseline, 787 grade one children (6-7-yr old) were examined and randomly allocated into a control and two treatment groups. At 20 months, 703 children remained in the study. The mean baseline caries experience and the mean number of permanent teeth present at 20 months were not significantly different among the treatment and control groups. The mean DMFS increments after 20 months were 1.70, 1.73 and 2.02 for Fluor-Protector, Duraphat and control groups respectively (% reductions of 15.8 and 14.4 for Fluor-Protector and Duraphat groups). The mean dfs increments for primary molars after 20 months were 1.56, 1.62 and 1.74 for Fluor-Protector, Duraphat and control groups respectively (% reductions of 10 for Fluor-Protector and 7 for Duraphat).

  13. Randomized clinical trial of four adhesion strategies in cervical lesions: 12-month results.

    Science.gov (United States)

    de Paula, Eloisa Andrade; Tay, Lidia Yileng; Kose, Carlos; Mena-Serrano, Alexandra; Reis, Alessandra; Perdigão, Jorge; Loguercio, Alessandro D

    2015-01-01

    The aim of this study was to evaluate the 6- and 12-month clinical performance of four adhesion strategies from the same manufacturer (Kerr) in non-carious cervical lesions (NCCLs) using two evaluation criteria. Thirty-five patients, with at least four NCCLs each, participated in this study. After samplesize calculation, 180 restorations were assigned to one of the following groups: OFL (Optibond FL), OSP (Optibond Solo Plus), XTR (Optibond XTR), and AIO (Optibond All-In-One). The composite resin Filtek Supreme Ultra (3M ESPE) was placed incrementally. The restorations were evaluated at baseline, after 6 months, and after 12 months, using both the FDI and the USPHS-modified criteria. Statistical analyses were performed with Friedman repeated measures, ANOVA by rank, and the McNemar test for significance in each pair (α=0.05). Six restorations (2 for OFL, 1 for OSP, 2 for XTR, and 1 for AIO) were lost at 12 months (P>0.05 for both evaluation criteria). Marginal staining was observed in seven restorations using the FDI criteria (P>0.05) and three restorations using the USPHSmodified criteria (P>0.05). Eight restorations (2 for OSP, 3 for XTR, and 3 for AIO) were classified as Bravo for marginal adaptation using the USPHSmodified criteria (P>0.05). However, 62 restorations (14 for OFL, 12 for OSP, 15 for XTR, and 21 for AIO) were classified as Bravo using the FDI criteria (P>0.05). The four adhesion strategies showed similar clinical retention at 6 and 12 months. The FDI evaluation criteria tend to be more sensitive than the USPHS-modified criteria.

  14. Simple instruments used in monitoring SID and some new results

    Science.gov (United States)

    Xiao, Zuo; Hao, Yongqiang; Zhang, Donghe; Xiao, Saiguan; Huang, Weiquan

    Sudden Ionospheric Disturbances are well known and commonly discussed topics. Some simple ground equipment was designed and used for monitoring continuously the effects of SIDs, especially, SWF and SFD. Besides SIDs, They also reflect clearly the acoustic gravity waves in different scale and Spread-F and these data are important supplementary to the traditional ionosonde records. It is of significance in understanding physical essentials of the ionospheric disturbances and applications in SID warning. In this paper, the designing of the instruments is given and results are discussed in detail. The results showed very clearly not only immediate effects of solar flare, but also the phenomena of ionospheric responses to Typhoon, great earthquake and volcano eruption, role of acoustic-gravity waves in seeding Spread-F.

  15. Ultrasonographic features of vascular closure devices: initial and 6-month follow-up results

    OpenAIRE

    Hye Jung Choo; Hae Woong Jeong; Jin Young Park; Sung-Chul Jin; Sung Tae Kim; Jung Hwa Seo; Sun Joo Lee; Young Mi Park

    2014-01-01

    Purpose:

    This study aimed to evaluate the ultrasonographic findings for various types of vascular closure devices (VCDs) immediately after the angiographic procedure and at 6-month follow-up.

    Methods:

    We included 18 VCDs including Angio-Seal (n=4), FemoSeal (n=8), ExoSeal (n=3), Perclose (n=...

  16. [Results of a multicentric study for the prevention of atopic allergy. 48 months of follow up].

    Science.gov (United States)

    Bruno, G; Giampietro, P G; Businco, L

    1996-10-01

    With the cooperation of 12 Maternity Hospitals we have started a prospective study to evaluate the effect of dietary and environmental measures in the development of atopic disease in "at risk" newborns. The preventive measures included: exclusive breast feeding for the first 6 months of life, soy milk supplement when breast milk is not sufficient, elimination of house dust, no smoking in the house, etc. All infants were seen at the age of 1, 3, 6, 9, 12 months and twice-a-year afterwards. 1213 babies have been enrolled. At the last follow-up of 48 months 531 children are 4 year old. The cumulative prevalence of atopic disease was 20%: 11 (2%) children developed atopic dermatitis, 69 (13%) asthma, 21 (4%) rinithis, 5 (1%) urticaria. The low prevalence of atopic disease and the trivial course of the allergic manifestations in the children who followed the preventive measures (78/444 = 18%) and the higher (28/87 = 32%) in these who did not (p < 0.01) stressed the importance of such manipulations for the prevention of atopy in "at risk" babies.

  17. The INGV seismic monitoring system: activities during the first month of the 2016 Amatrice seismic sequence.

    Science.gov (United States)

    Scognamiglio, L.; Margheriti, L.; Moretti, M.; Pintore, S.

    2016-12-01

    At 01:36:32 UTC on August 24, 2016 an earthquake of ML=6.0 occurred in Central Italy, near Amatrice village; 21 s after the origin time, the first automatic location became available while the first magnitude estimate followed 47s after. The INGV seismologists on duty provided the alert to the Italian Civil Protection Department and thereby triggered the seismic emergency protocol In the hours after the earthquake, hundreds of events were recorded by the Italian Seismic Network of the INGV. SISMIKO, the coordinating body of the emergency seismic network, was activated few minutes after the mainshock. The main goal of this emergency group is to install temporary dense seismic network integrated with the existing permanent networks in the epicentral area to better constrain the aftershock hypocenters. From August the 24th to the 30th, SISMIKO deployed 18 seismic stations, generally six components (equipped with both seismometer and accelerometer), 13 of which were transmitting in real-time to the INGV seismic surveillance room in Rome. All data acquired are available at the European Integrated Data Archive (EIDA). The seismic sequence in the first month generated thousands of earthquakes which were processed and detected by the INGV automated localization system. We analyzed the performance of this system. Hundreds of those events were located by seismologists on shifts, the others were left to be analyzed by the Bollettino Sismico Italiano (BSI). The procedures of the BSI revise and integrate all available data. This allows for a better constrained location and for a more realistic hypocentral depth estimation. The first eight hours of August 24th were the most critical for the INGV surveillance room. Data recorded in these hours were carefully re-analyzed by BSI operators and the number of located events increased from 133 to 408, while the magnitude of completeness dropped significantly from about 3.5 to 2.7.

  18. Results of monitoring at Olkiluoto in 2013, rock mechanics

    Energy Technology Data Exchange (ETDEWEB)

    Johansson, E. (ed.) [Saanio and Riekkola Oy, Helsinki (Finland)

    2014-10-15

    The rock mechanics monitoring at Olkiluoto concentrates on the assessment of potential tectonic movements and stability of the bedrock. The rock mechanics monitoring programme 2013 consisted of seismic measurements, GPS measurements, surface levelling measurements and temperature measurements at Olkiluoto and vicinity and displacement measurements, temperature measurements and visual tunnel observations made in the ONKALO. The Posiva's microseismic network consists of 17 seismic stations and 21 triaxial sensors. Five stations are in the ONKALO. In spite of few breaks the network operated continuously and well during 2013. The number of located events (436) was slightly more than in 2012, but much less than in 2011. Nearly half of the observed explosions (237) in 2013 occurred inside the seismic semi-regional area and especially inside the seismic ONKALO block (137). One small induced earthquake (M{sub L} = -1.8) was detected at the depth of 429 m and was probably associated with smaller branches of the brittle fracture zone (OL-BFZ045). According to the seismic monitoring the rock mass has been stable in 2013. The local GPS network consists of 18 stations. Six new stations were set up for permanent tracking during 2013 and in total 12 permanent stations are now operating continuously. Manual measurements were carried out twice in 2013. Most of the inner network baselines showed very small motions as in the previous years: 75% of change rates were smaller than 0.10 mm/y. Roughly one third of the change rates are statistically significant. The surface levelling network currently consists of 87 fixed measuring points. During 2013 all the measuring loops were measured. The results indicated local subsidence area in the ONKALO loop and the rising area in the VLJ loop. Mean deformation rate has been +0.05 mm/y. Only elevation of one benchmark in the GPS station loop has changed more than one millimetre. The continuous displacement measurements in the technical rooms

  19. Ultrasonographic features of vascular closure devices: initial and 6 month followup results

    Energy Technology Data Exchange (ETDEWEB)

    Choo, Hye Jung; Jeong, Hae Woong; Park, Jin Young; Kim, Sung Tae; Seo, Jung Hwa; Lee, Sun Joo; Park, Young Mi [Inje University Busan Paik Hospital, Inje University College of Medicine, Busan (Korea, Republic of); Jin, Sung Chul [Dept. of Neurosurgery, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan (Korea, Republic of)

    2014-12-15

    This study aimed to evaluate the ultrasonographic findings for various types of vascular closure devices (VCDs) immediately after the angiographic procedure and at 6-month follow-up. We included 18 VCDs including Angio-Seal (n=4), FemoSeal (n=8), ExoSeal (n=3), Perclose (n=2), and StarClose (n=1) in this study. Four patients were implanted with 2 VCDs at the each side of bilateral femoral arteries, while the remaining 8 patients were inserted 1 VCD at the right femoral artery. Ultrasonography was performed within 10 days and at approximately 6 months after the angiographic procedure. Ultrasonographic morphology of the attached VCD and its relationship with the arterial wall were analyzed. Initial ultrasonography revealed the attached VCD as the relevant unique structure with successful deployment and hemostasis. Follow-up ultrasonography demonstrated partial absorption of hemostatic materials in cases of Angio-Seal (n=3), FemoSeal (n=5), and ExoSeal (n=3), changes in the soft tissue surrounding the femoral artery in case of Angio-Seal (n=1), arterial intimal hyperplasia in cases of FemoSeal (n=3), and no gross changes as compared with the initial ultrasonographic findings in cases of Perclose (n=2) and StarClose (n=1). Initial ultrasonographic evaluation reflected the unique structure of each VCD, with most of them being easily distinguishable. Follow-up ultrasonography revealed various changes in the affected vessels.

  20. Solvent Hold Tank Sample Results for MCU-16-348-349-350: March 2016 Monthly Sample

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Jones, D. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-05-17

    Savannah River National Laboratory (SRNL) received one set of Solvent Hold Tank (SHT) samples (MCU-16-348-349-350), pulled on 03/30/2016 for analysis. The samples were combined and analyzed for composition. Analysis of the composite sample MCU-16-348-349-350 indicated the IsoparTML concentration is above its nominal level (101%). The modifier (CS-7SB) and the TiDG concentrations are 9% and 55% below their nominal concentrations. This analysis confirms the solvent may require the addition of TiDG, and possibly of modifier. Based on the current monthly sample, the levels of TiDG, IsoparTML, MaxCalix, and modifier are sufficient for continuing operation but are expected to decrease with time. Periodic characterization and trimming additions to the solvent are recommended.

  1. Solvent Hold Tank Sample Results for MCU-16-270-271-272: February 2016 Monthly Sample

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Jones, D. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-05-12

    Savannah River National Lab (SRNL) received one set of Solvent Hold Tank (SHT) samples (MCU-16-270-271-272), pulled on 02/21/2016 for analysis. The samples were combined and analyzed for composition. Analysis of the composite sample MCU-16-270-271-272 indicated the IsoparTML concentration is above its nominal level (101%). The modifier (CS-7SB), the extractant (MaxCalix), and the TiDG concentrations are 7%, 6%, and 40% below their nominal concentrations. This analysis confirms the addition of TiDG, MaxCalix, and modifier to the solvent in November 2015. Based on the current monthly sample, the levels of TiDG, IsoparTML, MaxCalix, and modifier are sufficient for continuing operation but are expected to decrease with time. Periodic characterization and trimming additions to the solvent are recommended.

  2. Solvent Hold Tank Sample Results for MCU-16-934-935-936: June 2016 Monthly Sample

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Jones, D. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-08-30

    Savannah River National Laboratory (SRNL) received one set of Solvent Hold Tank (SHT) samples (MCU-16-934-935-936), pulled on 07/01/2016 for analysis. The samples were combined and analyzed for composition. Analysis of the composite sample MCU-16-934-935-936 indicated the Isopar™L concentration is above its nominal level (101%). The modifier (CS-7SB) and the TiDG concentrations are 8% and 29 % below their nominal concentrations. This analysis confirms the solvent may require the addition of TiDG, and possibly of modifier. Based on the current monthly sample, the levels of TiDG, Isopar™L, MaxCalix, and modifier are sufficient for continuing operation but are expected to decrease with time. Periodic characterization and trimming additions to the solvent are recommended.

  3. Solvent Hold Tank Sample Results for MCU-16-596-597-598: April 2016 Monthly Sample

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL). Advanced Characterization and Processing; Jones, D. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL). Research Support

    2016-07-12

    Savannah River National Laboratory (SRNL) received one set of Solvent Hold Tank (SHT) samples (MCU-16-596-597-598), pulled on 04/30/2016 for analysis. The samples were combined and analyzed for composition. Analysis of the composite sample MCU-16-596-597-598 indicated the Isopar™L concentration is above its nominal level (102%). The modifier (CS-7SB) is 14% below its nominal concentration, while the TiDG and MaxCalix concentrations are at and above their nominal concentrations, respectively. This analysis confirms the solvent may require the addition of modifier. Based on the current monthly sample, the levels of TiDG, Isopar™L, MaxCalix, and modifier are sufficient for continuing operation but are expected to decrease with time. Periodic characterization and trimming additions to the solvent are recommended.

  4. Solvent hold tank sample results for MCU-16-1363-1365. November 2016 monthly sample

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Jones, D. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-03-22

    Savannah River National Laboratory (SRNL) received one set of three Solvent Hold Tank (SHT) samples (MCU-16-1363-1364-1365), pulled on 11/15/2016 for analysis. The samples were combined and analyzed for composition. Analysis of the composite sample MCU-16-1363-1364-1365 indicated the Isopar™L concentration is at its nominal level (100%). The extractant (MaxCalix) and the modifier (CS- 7SB) are 8% and 2 % below their nominal concentrations. The suppressor (TiDG) is 7% below its nominal concentration. This analysis confirms the trim and Isopar™ additions to the solvent in November. This analysis also indicates the solvent did not require further additions. Based on the current monthly sample, the levels of TiDG, Isopar™L, MaxCalix, and modifier are sufficient for continuing operation but are expected to decrease with time. Periodic characterization and trimming additions to the solvent are recommended.

  5. Monitoring of Zinc level in Milk of Breastfeeding Mothers at First Month of Delivery

    Directory of Open Access Journals (Sweden)

    Mohammad Hossien Salmani Nodoushan

    2015-03-01

    Materials and Methods: This was a descriptive study of 150 breastfeeding mothers in the 2014 who had given birth in Yazd and were sampled in a simple way. Sampling was done exclusively in the health and treatment centers in the city, in the spring of 2014. 10- 20 ml samples of breast milk were taken manually in the morning and before infants' feeding, in 3 times of 5, 15 and 30 days after delivery, to measure the micronutrient of zinc. The concentration of zinc was measured by atomic absorption spectroscopy.Data obtained by questionnaires and atomic absorption was analyzed by ANOVA test. Results: The average age of mothers was 27.40 ± 4.67 years. The average level of zinc in breast milk was 2.60 ± 0.35 mg/l. The zinc concentration of breast milk was at the bottom of the standard range of zinc in breast milk.There was no significant relationship between zinc averages in milk with education, age, BMI and mothers' job. But, there was a direct relationship between zinc levels of breast milk with mothers' BMI. Conclusion: According to the results of this study, it seems that addition of zinc to the diet of breastfeeding mothers helps to prevent zinc deficiency in mothers' blood serum as well as children's nutrition.

  6. [Surgical results and monitoring of postoperative atrial myxomas].

    Science.gov (United States)

    Tarelo-Saucedo, Juan M; Peñaloza-Guadarrama, Mario; Villela-Caleti, Jorge; García-Cruz, Adriana; Arizmendi-Monroy, Dulce K; Reynada-Torres, Jose L; Martinez-Ramirez, Leonel

    2016-01-01

    To analyze the casuistics of left atrial myxoma with emphasis on results and follow-up. We reviewed the clinical records of patients operated in the Hospital Cardiac Myxomas South Central High Specialty (HCSAE) of PEMEX in the last 7 years, with an emphasis on results and follow-up. The analysis showed 10 patients, of whom 60% were female and 40% male, with ages from 12 to 76 years, with a mean age of 50 years. In the clinical characteristics of patients predominated dyspnea in 90%, followed by fatigue (80%) and chest pain (60%). The incidence was 90% for the left atrium and 10% for the right atrium, had tumors less than 3cm to up to over 10cm (average of 6 to 7cm). The pathology report was myxoma in the 100% of cases, the morbidity and early mortality was 0%, with a mean hospital stay of 6 days, and a patient of 12 years of age recurred and underwent surgery five months later. The 5-year survival was 100%. The incidence of myxomas is well known for rare presentation, the experience in this national medical center is one patient for every 350 operations, one case per year with no mortality and excellent survival. Copyright © 2015 Instituto Nacional de Cardiología Ignacio Chávez. Published by Masson Doyma México S.A. All rights reserved.

  7. Solvent Hold Tank Sample Results for MCU-16-934-935-936: June 2016 Monthly Sample

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Jones, D. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-08-30

    Savannah River National Laboratory (SRNL) received one set of Solvent Hold Tank (SHT) samples (MCU-16-934-935-936), pulled on 07/01/2016 for analysis. The samples were combined and analyzed for composition. Analysis of the composite sample MCU-16-934-935-936 indicated the Isopar™L concentration is above its nominal level (101%). The modifier (CS-7SB) and the TiDG concentrations are 8% and 29 % below their nominal concentrations. This analysis confirms the solvent may require the addition of TiDG, and possibly of modifier. Based on the current monthly sample, the levels of TiDG, Isopar™L, MaxCalix, and modifier are sufficient for continuing operation but are expected to decrease with time. Periodic characterization and trimming additions to the solvent are recommended. No impurities above the 1000 ppm level were found in this solvent by the Semi-Volatile Organic Analysis (SVOA). No impurities were observed in the Hydrogen Nuclear Magnetic Resonance (HNMR). However, up to 21.1 ± 4 micrograms of mercury per gram of solvent (or 17.5 μg/mL) was detected in this sample (as determined by the XRF method of undigested sample). The current gamma level (1.41E5 dpm/mL) confirmed that the gamma concentration has returned to previous levels (as observed in the late 2015 samples) where the process operated normally and as expected.

  8. Solvent Hold Tank Sample Results for MCU-16-1247-1248-1249: August 2016 Monthly Sample

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Jones, D. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-01-12

    Savannah River National Laboratory (SRNL) received one set of Solvent Hold Tank (SHT) samples (MCU-16-1247-1248-1249), pulled on 08/22/2016 for analysis. The samples were combined and analyzed for composition. Analysis of the composite sample MCU-16-1247-1248-1249 indicated the Isopar™L concentration is above its nominal level (101%). The extractant (MaxCalix) and the modifier (CS-7SB) are 7% and 9 % below their nominal concentrations. The suppressor (TiDG) is 63% below its nominal concentration. This analysis confirms the solvent may require the addition of TiDG, and possibly of modifier and MaxCalix to restore then to nominal levels. Based on the current monthly sample, the levels of TiDG, Isopar™L, MaxCalix, and modifier are sufficient for continuing operation but are expected to decrease with time. Periodic characterization and trimming additions to the solvent are recommended. At the time of writing this report, A solvent trim batch containing TiDG, modifier and MaxCalix, was added to the SHT (October 2016) and expect the concentration of these components to be at their nominal values.

  9. Sustained Weight Loss with Vagal Nerve Blockade but Not with Sham: 18-Month Results of the ReCharge Trial

    Directory of Open Access Journals (Sweden)

    Scott A. Shikora

    2015-01-01

    Full Text Available Background/Objectives. Vagal block therapy (vBloc is effective for moderate to severe obesity at one year. Subjects/Methods. The ReCharge trial is a double-blind, randomized controlled clinical trial of 239 participants with body mass index (BMI of 40 to 45 kg/m or 35 to 40 kg/m with one or more obesity-related conditions. Interventions were implantation of either vBloc or Sham devices and weight management counseling. Mixed models assessed percent excess weight loss (%EWL and total weight loss (%TWL in intent-to-treat analyses. At 18 months, 142 (88% vBloc and 64 (83% Sham patients remained enrolled in the study. Results. 18-month weight loss was 23% EWL (8.8% TWL for vBloc and 10% EWL (3.8% TWL for Sham (P<0.0001. vBloc patients largely maintained 12-month weight loss of 26% EWL (9.7% TWL. Sham regained over 40% of the 17% EWL (6.4% TWL by 18 months. Most weight regain preceded unblinding. Common adverse events of vBloc through 18 months were heartburn/dyspepsia and abdominal pain; 98% of events were reported as mild or moderate and 79% had resolved. Conclusions. Weight loss with vBloc was sustained through 18 months, while Sham regained weight between 12 and 18 months. vBloc is effective with a low rate of serious complications.

  10. Results from two years of resistivity monitoring at Cerro Prieto

    Energy Technology Data Exchange (ETDEWEB)

    Wilt, M.J.; Goldstein, N.E.

    1981-01-01

    Dipole-dipole resistivity measurements for the combined purposes of reservoir delineation and resistivity monitoring were first made at Cerro Prieto in 1978 and have continued on an annual basis since then. Two 20 km long dipole-dipole lines with permanently emplaced electrodes at one kilometer spacings were established over the field area; one of these lines is remeasured annually. Resistivity measurements are taken using a 25 kW generator capable of up to 80A output and a microprocessor controlled signal averaging receiver; this high power-low noise system is capable of highly accurate measurements even at large transmitter-receiver separations. Standard error calculations for collected data indicate errors less than 5% for all points, but 95% confidence intervals show error limits about 2 to 4 times higher. Analysis of collected data indicate little change in the apparent resistivity of the upper 300 m over the field production zone and that in this section measurements are relatively insensitive to the annual rainfall cycle. Apparent resistivity increases were observed over the older producing zone at Cerro Prieto at depths of 1 km and greater. Large zones of decreasing apparent resistivity were observed flanking the zone of increases on both sides. The increase in apparent resistivity in the production region may be due to an increasing fraction of steam in the reservoir resulting from a production related decline in reservoir pressure. Alternatively the increases may be the result of fresh water influx from the Colorado River. The zone of declining resistivity flanking the area of increase may be due to the movement of saline waters into the reservoir region as a result of the pressure decline. Quantitative modeling of observed changes is impractical owing to the high uncertainty in estimating apparent resistivity changes and the nonuniqueness of models.

  11. Results of groundwater monitoring at Everest, Kansas, in April 2008.

    Energy Technology Data Exchange (ETDEWEB)

    LaFreniere, L. M.; Environmental Science Division

    2008-11-05

    constrain the existing contaminant plume. (c) Resampling of all existing permanent monitoring points for VOCs and biodegradation parameter analyses, at the request of the KDHE. On the basis of these studies (Argonne 2006a,b) and the CCC/USDA's past investigations at Everest (Argonne 2006c), the CCC/USDA concluded that groundwater extraction is not an effective remedial option for the main body of the groundwater plume, and the KDHE concurred (KDHE 2006); the KDHE later noted, however (KDHE 2007a), that this and other technologies might represent viable remedial options in the event of further downgradient migration of the plume toward the intermittent creek. In February 2007, the CCC/USDA presented preliminary analyses of (1) the AS-SVE remedial alternative, incorporating the use of LDBs, and (2) the risks to human health and the environment posed by the observed carbon tetrachloride plume in groundwater (Argonne 2007a). The results of these analyses demonstrated the following: (1) Neither groundwater extraction nor AS-SVE in LDBs represents a practical approach for effective remediation of the groundwater contamination at Everest (near the Nigh property). (2) Periodic sampling and analyses for VOCs conducted by the CCC/USDA documented that the areal extent and range of carbon tetrachloride concentrations detected in the groundwater plume at Everest had changed relatively little from 2000 to 2006. (3) Estimates of groundwater flow and contaminant migration times, based on the hydrogeologic properties of the groundwater flow system identified at Everest (Argonne 2003, 2006b,c), indicated that, at minimum, approximately 4 years would be required for the carbon tetrachloride plume (in the subsurface) to reach the vicinity of the intermittent creek directly west of the Nigh property, and more than 20 years would be required for the contamination to reach the identified groundwater discharge area southwest of the Nigh property. (4) The existing (January-March 2006) plume

  12. Updated Results from the COS Spectroscopic Sensitivity Monitoring Program

    Science.gov (United States)

    Osten, Rachel A.; Massa, Derck; Bostroem, Azalee; Aloisi, Alessandra; Proffitt, Charles

    2011-06-01

    We report updated results from the Cosmic Origins Spectrograph spectroscopic sensitivity monitoring programs utilizing data taken through the end of Cycle 17 and beginning of Cycle 18. Earlier results (reported in Osten et al. 2010) had indicated a wavelengthdependent decline of the FUV sensitivity which was worse at longer wavelengths. Since mid-March 2010, the rate of this sensitivity decline has become much smaller and mostly wavelength independent, and the rate of decline is now between 2 and 5%/year for all Far-Ultraviolet (FUV) gratings with sufficient signal to characterize. The characteristics of the FUV sensitivity decline are consistent with degradation of the quantum efficiency of the CsI photocathode of the FUV detector. The initial steep decline may have been caused by water vapor outgassing after COS's installation, while the subsequent decline may be due to exposure to ambient atomic oxygen present at HST's orbital altitude. New FUV Time-Dependent Sensitivity (TDS) reference files have been delivered to correct the pipeline flux calibration, however, even after the application of these TDS corrections there remain discrepancies in the absolute flux calibration which appear to depend on central wavelength and FP-POS, and can be up to 5-10%. Further investigation reveals that some of this discrepancy may be due to additional sensitivity degradation during initial on-orbit operations. As reported in Osten et al. (2010), the two NUV bare-aluminum gratings (G225M and G285M) are also showing sensitivity declines, which appear to continue trends seen during ground testing, and which may be due to ongoing evolution of an oxide layer. In contrast, the throughputs of the NUV gratings coated with MgF2 (G185M and G230L) remain stable, showing little to no sensitivity decline. The NUV bare-aluminum sensitivity decline appears to be a continuing trend from that seen on the ground.

  13. Results of a Second Year of Therapy with the 12-Month Histrelin Implant for the Treatment of Central Precocious Puberty

    Directory of Open Access Journals (Sweden)

    Shulman Dorothy

    2009-02-01

    Full Text Available Background. Gonadotropin releasing hormone analogs (GnRHas are standard of care for central precocious puberty (CPP. The histrelin subcutaneous implant is safe and effective in the treatment of CPP for one year. Objective. The study evaluates a second year of therapy in children with CPP who received a new implant after one year of treatment. Methods. A prospective one-year study following an initial 12-month treatment period was conducted. Results. Thirty-one patients (29 girls aged years received a second implant. Eighteen were naïve to GnRHa therapy at first implantation. Peak LH declined from  mIU/mL at 12 months to  mIU/mL at 24 months ( mIU/mL at 12 months to  mIU/mL at 24 months ( in previously treated subjects. Predicted adult height increased by 5.1 cm at 24 months (. Minor implant site reactions occurred in 61%, while minor difficulties with explantation occurred in 32.2% of subjects. Conclusion. The histrelin implant demonstrates profound hypothalamic-pituitary-gonadal axis suppression when a new implant is placed for a second year of treatment. Prospective follow-up of this therapeutic modality for the treatment of CPP is needed.

  14. The European CRT Survey : 1 year (9-15 months) follow-up results

    NARCIS (Netherlands)

    Bogale, Nigussie; Priori, Silvia; Cleland, John G. F.; Brugada, Josep; Linde, Cecilia; Auricchio, Angelo; van Veldhuisen, Dirk J.; Limbourg, Tobias; Gitt, Anselm; Gras, Daniel; Stellbrink, Christoph; Gasparini, Maurizio; Metra, Marco; Derumeaux, Genevieve; Gadler, Fredrik; Buga, Laszlo; Dickstein, Kenneth

    2012-01-01

    Aims The European CRT Survey is a joint initiative of the Heart Failure Association (HFA) and the European Heart Rhythm Association (EHRA) of the European Society of Cardiology evaluating the contemporary implantation practice of cardiac resynchronization therapy (CRT) in Europe. Methods and results

  15. The European CRT Survey : 1 year (9-15 months) follow-up results

    NARCIS (Netherlands)

    Bogale, Nigussie; Priori, Silvia; Cleland, John G. F.; Brugada, Josep; Linde, Cecilia; Auricchio, Angelo; van Veldhuisen, Dirk J.; Limbourg, Tobias; Gitt, Anselm; Gras, Daniel; Stellbrink, Christoph; Gasparini, Maurizio; Metra, Marco; Derumeaux, Genevieve; Gadler, Fredrik; Buga, Laszlo; Dickstein, Kenneth

    Aims The European CRT Survey is a joint initiative of the Heart Failure Association (HFA) and the European Heart Rhythm Association (EHRA) of the European Society of Cardiology evaluating the contemporary implantation practice of cardiac resynchronization therapy (CRT) in Europe. Methods and results

  16. Analytical results from salt batch 9 routine DSSHT and SEHT monthly samples

    Energy Technology Data Exchange (ETDEWEB)

    Peters, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-06-01

    Strip Effluent Hold Tank (SEHT) and Decontaminated Salt Solution Hold Tank (DSSHT) samples from several of the “microbatches” of Integrated Salt Disposition Project (ISDP) Salt Batch (“Macrobatch”) 9 have been analyzed for 238Pu, 90Sr, 137Cs, cations (Inductively Coupled Plasma Emission Spectroscopy - ICPES), and anions (Ion Chromatography Anions - IC-A). The analytical results from the current microbatch samples are similar to those from previous macrobatch samples. The Cs removal continues to be acceptable, with decontamination factors (DF) averaging 25700 (107% RSD). The bulk chemistry of the DSSHT and SEHT samples do not show any signs of unusual behavior, other than lacking the anticipated degree of dilution that is calculated to occur during Modular Caustic-Side Solvent Extraction Unit (MCU) processing.

  17. European collaboration for improved monitoring of Icelandic volcanoes: Status of the FUTUREVOLC project after the initial 18 months

    Science.gov (United States)

    Dumont, Stéphanie; Parks, Michelle; Sigmundsson, Freysteinn; Vogfjörð, Kristín; Einarsdóttir, Heiðveig Maria; Tumi Gudmundsson, Magnús; Kristinsson, Ingvar; Loughlin, Sue; Ilyinskaya, Evgenia; Hooper, Andrew; Kylling, Arve; Witham, Claire; Bean, Chris; Braiden, Aoife; Ripepe, Maurizio; Prata, Fred; Pétur Heiðarsson, Einar; Other Members Of The Futurevolc Team

    2014-05-01

    The FUTUREVOLC project funded by the European Union (FP7) is devoted to volcanic hazard assessment and establishing an integrated volcanological monitoring procedure through a European collaboration. To reach these objectives the project combines broad expertise from 26 partners from 10 countries, focusing on the four most active volcanoes of Iceland: Grímsvötn, Katla, Hekla and Bárdarbunga. The geological setting of Iceland, the high rate of eruptions and the various eruption styles make this country an optimal natural laboratory to study volcanic processes from crustal depths to the atmosphere. The project, which began on 1 October 2012, integrates advanced monitoring and analytical techniques in an innovative way, focusing on (i) detailed monitoring to improve our understanding of the seismic/magmatic unrest, in order to estimate the amount of magma available for an eruption and to provide early warnings (ii) the dynamics of magma in the conduit and a near real time estimation of the mass eruption rate and (iii) observing and modelling the plume dynamics. The project design considers effective collaboration between partners and aims for efficient cross-disciplinary workflows. A major step during the first 18 months of the project was the installation of additional equipment in the volcanic regions of Iceland to reinforce and complement the existing monitoring. The instruments include: seismometers, GPS stations, MultigGAS detectors, DOAS, infrasonic arrays, electric field sensors, radars, and optical particle sizers. Data streaming is designed to withstand extreme weather conditions. The FUTUREVOLC project has an open data policy for real and near-time data. Implementation of a data hub is currently under way, based on open access to data from the 2010 Eyjafjallajökull eruption. Access to volcano monitoring data through a common interface will allow timely information on magma movements facilitated through combined analysis. A key part of the project is to

  18. Results of monitoring at Olkiluoto in 2009. Rock mechanics

    Energy Technology Data Exchange (ETDEWEB)

    Lahti, M. (ed.) (Posiva Oy, Helsinki (Finland)); Hakala, M. (KMS Hakala Oy, Nokia (Finland))

    2010-09-15

    The rock mechanical monitoring at Olkiluoto concentrates on the assessment of potential tectonic movements and stability of the bedrock. The construction of ONKALO is not expected to induce large-scale movements of the rock blocks or affect the rate of isostatic uplift but the evaluation of any tectonic events is important for the safety assessment. The monitoring consists of seismic measurements, GPS measurements and precise levelling campaigns at Olkiluoto and vicinity and additionally extensometer and convergence measurements carried out in ONKALO. Posiva established a local seismic network of six stations on the island of Olkiluoto in 2002. The number of seismic stations has increased gradually being in 2009 altogether 14. The purpose of the microearthquake measurements at Olkiluoto is to improve understanding of the structure, behaviour and long term stability of the bedrock. The investigation area includes two target areas. The larger target area, called seismic semi-regional area, covers the Olkiluoto Island and its surroundings. The purpose is to monitor explosions and tectonic earthquakes in regional scale. The smaller target area is s called the seismic ONKALO block, which is a 2 km 2 km 2 km cube surrounding the ONKALO. All the expected excavation induced events assumingly occur within this volume. At the moment the seismic ONKALO block includes 10 seismic stations. An additional task of monitoring is related to safeguarding of the ONKALO. The seismic network has operated continuously in 2009 and during the year altogether 1256 events have been located in the Olkiluoto area. Most of them (1161) are explosions that occurred inside the seismic semi-regional area and especially inside the seismic ONKALO block (1135 events)

  19. Graft function based on two hours peak level monitoring of cyclosporine A during the first six months of renal transplantation.

    Science.gov (United States)

    Hami, Maryam; Naghibi, Massih; Mojahedi, Mohammad Javad; Sharifipour, Farzaneh; Shakeri, Mohammad Taghi

    2012-11-01

    Inadequate cyclosporine blood levels may cause acute rejection in transplanted renal graft, and its increase is accompanied with graft toxicity. Cyclosporine has variable bioavailability and pharmacokinetics among patients at different times after transplantation. In this study, we compared the effects of cyclosporine blood levels (trough versus 2-hour peak, C2) on renal graft function during the first six months after transplantation in order to find better methods for drug levels assessment in our patients. We studied 50 patients who received grafts at Mashhad transplant centers from October 2006 to May 2007. Drug levels were monitored seven times during the study; in each assessment, more than 80% of the patients did not reach the therapeutic C2 levels. There was no significant correlation between age, sex, times of transplantation and acute rejection with drug C2 levels. There was no difference between graft function in patients with therapeutic C2 level and those with inadequate C2 levels. However, we found a significant correlation between trough levels and acute rejection (P transplantation was the drug dosage significantly higher in patients with therapeutic C2 level than that in other patients (P >0.05). Apparently, peak levels were not a suitable method in drug monitoring in our patients, or peak levels might have occurred at a different time (like 1.5 or 3 or 4 h after ingestion of the drug) in our population. Based on this study, trough level may be a better method of evaluation of cyclosporine effects on renal allografts than 2-h peak levels in our patients.

  20. Solvent hold tank sample results for MCU-15-802-803-804-805-806-807 August monthly sample

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Jones, D. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-01-01

    Savannah River National Laboratory (SRNL) received one set of Solvent Hold Tank (SHT) samples (MCU-15-802-803-804-805-806-807), pulled on 08/31/2015 for analysis. The samples were combined and analyzed for composition. Analysis of the composite sample MCU-15-802-803-804-805-806-807 indicated a low concentration (~ 45 % of nominal) of the suppressor (TiDG) and a slightly lower than nominal concentration of the modifier (Cs-7SB) in the solvent. The extractant (MaxCalix) concentration was at its nominal value. Based on this current monthly sample, the levels of TiDG, MaxCalix, and modifier were sufficient for continuing operation without adding a trim during that time but it is recommended that an addition of TiDG, modifier and Isopar™L should be made in the next few months. This monthly sample’s rheology, as determined by Hydrogen Nuclear Magnetic Resonance (H-NMR), is consistent with the rheology of the standard NGS solvent made in the lab (Scratch solvent 5/14/2014). No impurities above the 1000 ppm level were found in this solvent by the Semi-Volatile Organic Analysis (SVOA). No impurities were observed in the Hydrogen Nuclear Magnetic Resonance (HNMR). In addition, up to 16.7 micrograms of mercury per gram of solvent (or 14 μg/mL) was detected in this sample. The laboratory will continue to monitor the quality of the solvent in particular for any new impurities or degradation of the solvent components.

  1. Results of a Second Year of Therapy with the 12-Month Histrelin Implant for the Treatment of Central Precocious Puberty

    Directory of Open Access Journals (Sweden)

    Samar Rahhal

    2009-01-01

    Full Text Available Background. Gonadotropin releasing hormone analogs (GnRHas are standard of care for central precocious puberty (CPP. The histrelin subcutaneous implant is safe and effective in the treatment of CPP for one year. Objective. The study evaluates a second year of therapy in children with CPP who received a new implant after one year of treatment. Methods. A prospective one-year study following an initial 12-month treatment period was conducted. Results. Thirty-one patients (29 girls aged 7.7±1.5 years received a second implant. Eighteen were naïve to GnRHa therapy at first implantation. Peak LH declined from 0.92±0.58 mIU/mL at 12 months to 0.51±0.33 mIU/mL at 24 months (P < .0001 in naïve subjects, and from 0.74±0.50 mIU/mL at 12 months to 0.45±0.35 mIU/mL at 24 months (P=.0081 in previously treated subjects. Predicted adult height increased by 5.1 cm at 24 months (P=.0001. Minor implant site reactions occurred in 61%, while minor difficulties with explantation occurred in 32.2% of subjects. Conclusion. The histrelin implant demonstrates profound hypothalamic-pituitary-gonadal axis suppression when a new implant is placed for a second year of treatment. Prospective follow-up of this therapeutic modality for the treatment of CPP is needed.

  2. Persistence of psychological distress in surgical patients with interest in psychotherapy: results of a 6-month follow-up.

    Directory of Open Access Journals (Sweden)

    Léonie F Kerper

    Full Text Available OBJECTIVES: This prospective observational study investigated whether self-reported psychological distress and alcohol use problems of surgical patients change between preoperative baseline assessment and postoperative 6-month follow-up examination. Patients with preoperative interest in psychotherapy were compared with patients without interest in psychotherapy. METHODS: A total of 1,157 consecutive patients from various surgical fields completed a set of psychiatric questionnaires preoperatively and at 6 months postoperatively, including Patient Health Questionnaire-4 (PHQ-4, Brief Symptom Inventory (BSI, Center for Epidemiologic Studies Depression Scale (CES-D, World Health Organization 5-item Well-Being Index (WHO-5, and Alcohol Use Disorder Identification Test (AUDIT. Additionally, patients were asked for their interest in psychotherapy. Repeated measure ANCOVA was used for primary data analysis. RESULTS: 16.7% of the patients were interested in psychotherapy. Compared to uninterested patients, they showed consistently higher distress at both baseline and month 6 regarding all of the assessed psychological measures (p's between <0.001 and 0.003. At 6-month follow-up, neither substantial changes over time nor large time x group interactions were found. Results of ANCOVA's controlling for demographic variables were confirmed by analyses of frequencies of clinically significant distress. CONCLUSION: In surgical patients with interest in psychotherapy, there is a remarkable persistence of elevated self-reported general psychological distress, depression, anxiety, and alcohol use disorder symptoms over 6 months. This suggests high and chronic psychiatric comorbidity and a clear need for psychotherapeutic and psychiatric treatment rather than transient worries posed by facing surgery.

  3. Pre-registration adult nurses' knowledge of safe transfusion practice: Results of a 12 month follow-up study.

    Science.gov (United States)

    Smith, Fiona C; Donaldson, Jayne; Pirie, Liz

    2010-03-01

    This research project ascertained student nurses' knowledge retention of safe transfusion practice following a standardised teaching and learning programme (produced by the Scottish National Blood Transfusion Service, United Kingdom (UK)) within a School of Nursing in Scotland, UK. Several studies including the Serious Hazard of Transfusion (SHOT) annual reports demonstrated that there are risks to the patient in receiving blood components: receiving the wrong blood was the most common risk associated with blood transfusion (Ottewill, 2003; SHOT, 2007). This evaluative study used a questionnaire to assess the level of knowledge students (n=118) attained on the day of the session, 4-6 months and 11-12 months following the session. The study provided an insight into the effectiveness of a standardised teaching approach and highlighted areas for review in light of incorrect answers elicited. Despite all receiving the Standardised Programme, there was a wide range of initial overall scores achieved. The study demonstrated, within the small sample completing at all 3 time points, that there is clear degradation of knowledge during the study period. The influence of experience on knowledge retention appears to have a positive effect at 6 months but no appreciable effect at 12 months. These outcomes merit further, more robust and multi centre investigation to identify if there is replication of results.

  4. THE FIRST RUSSIAN STRATEGIC STUDY OF PHARMACOTHERAPY FOR RHEUMATOID ARTHRITIS (REMARCA TRIAL: RESULTS OF 12-MONTH TREATMENT IN 130 PATIENTS

    Directory of Open Access Journals (Sweden)

    D. E. Karateev

    2014-01-01

    Full Text Available To introduce treat-to-target recommendations is an important task of modern rheumatology; however, there is still a diversity of serious problems relating to a scientific rationale and a clinical one for this strategy and to the possibilities of its implementation in real clinical practice, in the rheumatology service of the Russian Federation in particular, by taking into account the specific features of funding for high-tech medical care.Objective: to determine the efficiency and safety of combined therapy with subcutaneous methotrexate (MT and biological agents (BA when using the treat-to-target strategy in patients with active early and extended-stage rheumatoid arthritis (RA who have risk factors for a poor prognosis.Subjects and methods.The results of the REMARCA (Russian InvEstigation of MethotrexAte and biologicals in eaRly aCtive inflammatory Arthritis trial of 130 patients followed up for 12 months or more were given. There was a female preponderance; mean age 48.9±13.9 years, rheumatoid factor positivity (86.9%; anti-cyclic citrullinated peptide antibody positivity (89.2%. Seventy patients formed a subgroup of early RA (disease duration ≤6 months (mean 4.17±1.39 months; 60 patients were a subgroup of advanced-stage RA (disease duration >6 months (mean 30.8±32.7 months. In all the patients, therapy was initiated by using subcutaneous MT with its rapid dose escalation up to 20–30 mg/week and the achievement of the treatment goal (low disease activity or remission was checked every 3 months and depending on the result a decision had been taken to add or not to add a biological agent (BA (a tumor necrosis factor inhibitor or abatacept. If the former was insufficiently effective, it was substituted for a BA from another class.Results. Subcutaneous MT monotherapy provided remission or low disease activity in 49 (37.7% patients; a BA was given to 81 (62.3% patients. Following 6 and 12 months, low activity or remission

  5. THE FIRST RUSSIAN STRATEGIC STUDY OF PHARMACOTHERAPY FOR RHEUMATOID ARTHRITIS (REMARCA TRIAL: RESULTS OF 12-MONTH TREATMENT IN 130 PATIENTS

    Directory of Open Access Journals (Sweden)

    D. E. Karatee

    2016-01-01

    Full Text Available To introduce treat-to-target recommendations is an important task of modern rheumatology; however, there is still a diversity of serious problems relating to a scientific rationale and a clinical one for this strategy and to the possibilitiesof its implementation in real clinical practice, in the rheumatology service of the Russian Federation in particular, by taking into account the specific features of funding for high-tech medical care.Objective: to determine the efficiency and safety of combined therapy with subcutaneous methotrexate (MT and biological agents (BA when using the treat-to-target strategy in patients with active early and extended-stage rheumatoid arthritis (RA who have risk factors for a poor prognosis.Subjects and methods. The results of the REMARCA (Russian InvEstigation of MethotrexAte and biologicals in eaRly aCtive inflammatory Arthritis trial of 130 patients followed up for 12 months or more were given. There was a female preponderance; mean age 48.9±13.9 years, rheumatoid factor positivity (86.9%; anti-cyclic citrullinated peptide anti body positivity (89.2%. Seventy patients formed a subgroup of early RA (disease duration ≤6 months (mean 4.17±1.39 months; 60 patients were a subgroup of advanced-stage RA (disease duration >6 months (mean 30.8±32.7 months. In all the patients, therapy was initiated by using subcutaneous MT with its rapid dose escalation up to 20–30 mg/week and the achievement of the treatment goal (low disease activity or remission was checked every 3 months and depending on the result a decision had been taken to add or not to add a biological agent (BA (a tumor necrosis factor inhibitor or abatacept. If the former was insufficientlyeffective, it was substituted for a BA from another class.Results. Subcutaneous MT monotherapy provided remission or low disease activity in 49 (37.7% patients; a BA was given to 81 (62.3% patients. Following 6 and 12 months, low activity or remission according to

  6. THE FIRST RUSSIAN STRATEGIC STUDY OF PHARMACOTHERAPY FOR RHEUMATOID ARTHRITIS (REMARCA TRIAL: RESULTS OF 12-MONTH TREATMENT IN 130 PATIENTS

    Directory of Open Access Journals (Sweden)

    D. E. Karateev

    2015-01-01

    Full Text Available To introduce treat-to-target recommendations is an important task of modern rheumatology; however, there is still a diversity of serious problems relating to a scientific rationale and a clinical one for this strategy and to the possibilities of its implementation in real clinical practice, in the rheumatology service of the Russian Federation in particular, by taking into account the specific features of funding for high-tech medical care. Objective: to determine the efficiency and safety of combined therapy with subcutaneous methotrexate (MT and biological agents (BA when using the treat-to-target strategy in patients with active early and extended-stage rheumatoid arthritis (RA who have risk factors for a poor prognosis. Subjects and methods. The results of the REMARCA (Russian InvEstigation of MethotrexAte and biologicals in eaRly aCtive inflammatory Arthritis trial of 130 patients followed up for 12 months or more were given. There was a female preponderance; mean age 48.9±13.9 years, rheumatoid factor positivity (86.9%; anti-cyclic citrullinated peptide antibody positivity (89.2%. Seventy patients formed a subgroup of early RA (disease duration ≤6 months (mean 4.17±1.39 months; 60 patients were a subgroup of advanced-stage RA (disease duration >6 months (mean 30.8±32.7 months. In all the patients, therapy was initiated by using subcutaneous MT with its rapid dose escalation up to 20–30 mg/week and the achievement of the treatment goal (low disease activity or remission was checked every 3 months and depending on the result a decision had been taken to add or not to add a biological agent (BA (a tumor necrosis factor inhibitor or abatacept. If the former was insufficiently effective, it was substituted for a BA from another class. Results. Subcutaneous MT monotherapy provided remission or low disease activity in 49 (37.7% patients; a BA was given to 81 (62.3% patients. Following 6 and 12 months, low activity or remission according

  7. [Preliminary results of antibiotic resistance monitoring in the Netherlands].

    Science.gov (United States)

    Mevius, D J; Veldman, K T; van der Giessen, A; van Leeuwen, W J

    2000-03-01

    Qualitative tests are used to monitor antimicrobial resistance in bacteria of animal origin in the Netherlands. Quantitative information on trends in resistance is thus not obtained. Moreover, in general a limited panel of antibiotics is tested. The present study describes resistance in zoonotic food-borne pathogens Salmonella, Campylobacter, and Escherichia coli O157 isolated from human clinical cases and from faeces of healthy food animals in 1998 and 1999, as determined with quantitative susceptibility tests. The resistance of the indicator organisms E. coli and Enterococcus faecium isolated from faecal samples of broilers and pigs randomly sampled at slaughterhouses was also determined. For this end, faecal samples from veal calves were sampled in 1996 and 1997 at the three main Dutch veal calf slaughterhouses. In 1998 only a limited number of faecal samples of veal calves were taken at farms. For E. coli and Salmonella the following antibiotics were tested: amoxicillin, amoxicillin-clavulanic acid, piperacillin, cefotaxime, ceftazidime, imipenem, gentamicin, doxycycline, trimethoprim, trimethoprim/sulphamethoxazole, ciprofloxacin, chloramphenicol, florfenicol, carbadox, and flumequine. For E. faecium the following antibiotics were tested: amoxicillin, amoxicillin-clavulanic acid, chloramphenicol, doxycycline, erythromycin, vancomycin, teicoplanin, streptomycin ('high level' > 2000 mg/ml), gentamicin ('high level' > 500 mg/ml), ciprofloxacin, bacitracin, flavofosfolipol, salinomycin, quinupristin-dalfopristin, virginiamycin, tilmicosin, avilamycin, and everninomycin. For Campylobacter the following antibiotics were tested: erythromycin, doxycycline, gentamicin, carbadox, flavofosfolipol, ciprofloxacin, trimethoprim/sulphamethoxazole, amoxicillin, and metronidazole.

  8. First measurements results of the LHC longitudinal density monitor

    CERN Document Server

    Jeff , A; Bravin, E; Boccardi, A; Bozyigit, S; Lefevre, T; Rabiller, A; Roncarolo, F; Welsch, C P; Fisher, A S

    2011-01-01

    Knowledge of the longitudinal distribution of particles is important for various aspects of accelerator operation, for example to check the injection quality and to characterize the development of ghost bunches before and during the physics periods. A new detector, the LHC Longitudinal Density Monitor (LDM) is a single-photon counting system measuring synchrotron light by means of an avalanche photodiode detector. The unprecedented energies reached in the LHC allow synchrotron light diagnostics to be used with both protons and heavy ions. The LDM is able to longitudinally profile the whole ring with a resolution close to the target of 50 ps. On-line correction for the effects of the detector deadtime, pile-up and afterpulsing allow a dynamic range of 105 to be achieved. The LDM operated during the 2010 lead ion run and during 2011 with protons. Measurements from both runs are presented in this contribution along with an analysis of the LDM performance and an outlook for future upgrades.

  9. First results of the LHC longitudinal density monitor

    CERN Document Server

    Jeff, A; Bravin, E; Fisher, AS; Lefevre, T; Rabiller, A; Roncarolo, F; Welsch, C P

    2011-01-01

    The Large Hadron Collider (LHC) at CERN is the world's largest particle accelerator. It is designed to accelerate and collide protons or heavy ions up to the center-of-mass energies of 14 TeV. Knowledge of the longitudinal distribution of particles is important for various aspects of accelerator operation, in particular to check the injection quality and to measure the proportion of charge outside the nominally filled bunches during the physics periods. In order to study this so-called ghost charge at levels very much smaller than the main bunches, a longitudinal profile measurement with a very high dynamic range is needed. A new detector, the LHC Longitudinal Density Monitor (LDM) is a single-photon counting system measuring synchrotron light by means of an avalanche photodiode detector. The unprecedented energies reached in the LHC allow synchrotron light diagnostics to be used with both protons and heavy ions. A prototype was installed during the 2010 LHC run and was able to longitudinally profile the whol...

  10. First Results of the LHC Longitudinal Density Monitor

    Energy Technology Data Exchange (ETDEWEB)

    Jeff, A.; /CERN /Liverpool U.; Boccardi, A.; /CERN; Bravin, E.; /CERN; Fisher, A.S.; /SLAC; Lefevre, T.; /CERN; Rabiller, A.; /CERN; Roncarolo, F.; /CERN; Welsch, C.P.; /Liverpool U. /Cockcroft Inst. Accel. Sci. Tech.

    2012-04-19

    The Large Hadron Collider (LHC) at CERN is the world's largest particle accelerator. It is designed to accelerate and collide protons or heavy ions up to the center-of-mass energies of 14 TeV. Knowledge of the longitudinal distribution of particles is important for various aspects of accelerator operation, in particular to check the injection quality and to measure the proportion of charge outside the nominally filled bunches during the physics periods. In order to study this so-called ghost charge at levels very much smaller than the main bunches, a longitudinal profile measurement with a very high dynamic range is needed. A new detector, the LHC Longitudinal Density Monitor (LDM) is a single-photon counting system measuring synchrotron light by means of an avalanche photodiode detector. The unprecedented energies reached in the LHC allow synchrotron light diagnostics to be used with both protons and heavy ions. A prototype was installed during the 2010 LHC run and was able to longitudinally profile the whole ring with a resolution close to the target of 50 ps. On-line correction for the effects of the detector deadtime, pile-up and afterpulsing allow a dynamic range of 105 to be achieved. First measurements with the LDM are presented here along with an analysis of its performance and an outlook for future upgrades.

  11. [Focused lithotripsy in the treatment of tendinosis calcarea of the shoulder: results at 2 months and one year].

    Science.gov (United States)

    Sarrat, P; Cohen, M; Carrasset, S; Godde, J; Franceschi, J P; Aswad, R

    2004-10-01

    The authors report their experience with extracorporeal lithotripsy in 30 patients with calcific tendinosis of the rotator cuff. This technique is based upon the utilization of high-energy shockwaves (6000 shocks in 3 sessions Day 1, D8, D30) under continuous ultrasound localization of the lesion (EPOS Ultra1). Calcification were evaluated at plain film, US and CT to characterize their length and features. Complete or partial resorption of calcifying deposits within 2 months and one year was observed in 27.5% and 25% of cases respectively. Clinical improvement results are encouraging at two months (50%), but reduced at one year (28.5%), consistent with the rate of resorption of calcifications. This painful, long, and expensive technique seems to be disappointing in the treatment of the calcific tendinosis.

  12. An extensively hydrolysed rice protein-based formula in the management of infants with cow's milk protein allergy: preliminary results after 1 month

    Science.gov (United States)

    Vandenplas, Yvan; De Greef, Elisabeth; Hauser, Bruno

    2014-01-01

    Background Guidelines recommend extensively hydrolysed cow's milk protein formulas (eHF) in the treatment of infants diagnosed with cow's milk protein allergy (CMPA). Extensively hydrolysed rice protein infant formulas (eRHFs) have recently become available, and could offer a valid alternative. Methods A prospective trial was performed to evaluate the clinical tolerance of a new eRHF in infants with a confirmed CMPA. Patients were followed for 1 month. Clinical tolerance of the eRHF was evaluated with a symptom-based score (SBS) and growth (weight and length) was monitored. Results Thirty-nine infants (mean age 3.4 months, range 0.5–6 months) diagnosed with CMPA were enrolled. All infants tolerated the eRHF and experienced a normal growth. Conclusions In accordance with current guidelines, this eRHF is tolerated by more than 90% of children with proven CMPA with a 95% CI, and is an adequate alternative to cow's milk-based eHF. Trial registration number ClinicalTrials.gov NCT01998074. PMID:24914098

  13. Percutaneous Stabilization System Osseofix® for Treatment of Osteoporotic Vertebral Compression Fractures - Clinical and Radiological Results after 12 Months.

    Directory of Open Access Journals (Sweden)

    Stephan Albrecht Ender

    Full Text Available A prospective consecutive cohort study (follow-up study.Our study investigated whether implantation of an expandable titanium mesh cage (Osseofix® is a successful and safe minimally invasive therapy for osteoporotic vertebral compression fractures (VCF. Our experiences, clinical and radiological findings after 12 months follow-up are presented. Kypho- and vertebroplasty are well-established minimally invasive procedures for the treatment of osteoporotic VCF. The main complications associated with both procedures are uncontrolled bone cement leakage. Therefore a suitable alternative has been investigated.During June 2010 to May 2011 24 patients were included with 32 osteoporotic VCF (T6 to L4. All of them were stabilized with the Osseofix® system. Preinterventionally we performed X-ray, MRI, and bone density measurements (DXA. Clinical and radiological results were evaluated preop., postop. and after 12 months postop. based on the Oswestry Disability Index (ODI and the Visual Analogue Scale (VAS, X-ray (Beck Index, Cobb-angle and CT.There was a significant improvement in the mean ODI (70,6% to 30,1% as well as a significant reduction in pain intensity (VAS (7,7 to 1,4 after 12 month. The mean kyphotic angle according to Cobb showed significant improvements (11,7° to 10,4° after 12 months. Postinterventional imaging showed only one case of loss of height in a stabilized vertebral body (3.1%. We saw no changes in posterior vertebral wall or adjacent fractures. Except for one pronounced postoperative hematoma we saw no surgical complications including no cement leakage.Stabilization of symptomatic osteoporotic VCF with Osseofix® system is a safe and effective procedure, even in fractures with posterior wall involvement. The clinical mid-term results are good at a very low complication rate. The Osseofix® system is an interesting alternative to the established procedures of cement augmentation.

  14. Amchitka Island, Alaska, Biological Monitoring Report 2011 Sampling Results

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-09-01

    The Long-Term Surveillance and Maintenance (LTS&M) Plan for the U.S. Department of Energy (DOE) Office of Legacy Management (LM) Amchitka Island sites describes how LM plans to conduct its mission to protect human health and the environment at the three nuclear test sites located on Amchitka Island, Alaska. Amchitka Island, near the western end of the Aleutian Islands, is approximately 1,340 miles west-southwest of Anchorage, Alaska. Amchitka is part of the Aleutian Island Unit of the Alaska Maritime National Wildlife Refuge, which is administered by the U.S. Fish and Wildlife Service (USFWS). Since World War II, Amchitka has been used by multiple U.S. government agencies for various military and research activities. From 1943 to 1950, it was used as a forward air base for the U.S. Armed Forces. During the middle 1960s and early 1970s, the U.S. Department of Defense (DOD) and the U.S. Atomic Energy Commission (AEC) used a portion of the island as a site for underground nuclear tests. During the late 1980s and early 1990s, the U.S. Navy constructed and operated a radar station on the island. Three underground nuclear tests were conducted on Amchitka Island. DOD, in conjunction with AEC, conducted the first nuclear test (named Long Shot) in 1965 to provide data that would improve the United States' capability of detecting underground nuclear explosions. The second nuclear test (Milrow) was a weapons-related test conducted by AEC in 1969 as a means to study the feasibility of detonating a much larger device. Cannikin, the third nuclear test on Amchitka, was a weapons-related test detonated on November 6, 1971. With the exception of small concentrations of tritium detected in surface water shortly after the Long Shot test, radioactive fission products from the tests remain in the subsurface at each test location As a continuation of the environmental monitoring that has taken place on Amchitka Island since before 1965, LM in the summer of 2011 collected biological

  15. Improving Physical Health in Patients with Chronic Mental Disorders: 12-Month Results from a Randomized Controlled Collaborative Care Trial

    Science.gov (United States)

    Kilbourne, Amy M.; Barbaresso, Michelle M.; Lai, Zongshan; Nord, Kristina M.; Bramlet, Margretta; Goodrich, David E.; Post, Edward P.; Almirall, Daniel; Bauer, Mark S.

    2015-01-01

    Objective Persons with chronic mental disorders are disproportionately burdened with physical health conditions. We determined whether Life Goals Collaborative Care compared to usual care improves physical health in patients with mental disorders within 12 months. Method This single-blind randomized controlled effectiveness study of a collaborative care model was conducted at a mid-western Veterans Affairs urban outpatient mental health clinic. Patients (N=293 out of 474 eligible approached) with an ICD-9-CM diagnosis of schizophrenia, bipolar disorder, or major depressive disorder and at least one cardiovascular disease risk factor were consented and randomized (02/24/10 to 04/29/15) to Life Goals (N=146) or usual care (N=147). A total of 287 completed baseline assessments and 245 completed 12-month follow-up assessments. Life Goals included five weekly sessions that provided semi-structured guidance on managing physical and mental health symptoms through healthy behavior changes, augmented by ongoing care coordination. The primary outcome was change in physical health-related quality of life score (VR-12 physical health component score). Secondary outcomes included control of cardiovascular risk factors from baseline to 12 months (blood pressure, lipids, weight), mental health-related quality of life, and mental health symptoms. Results Among patients completing baseline and 12-month outcomes assessments (N=245), the mean age was 55.3 (SD=10.8; range 28-75 years) and 15.4% were female. Intent-to-treat analysis revealed that compared to those in usual care, patients randomized to Life Goals had slightly increased VR-12 physical health scores (coefficient=3.21;p=0.01). Conclusion Patients with chronic mental disorders and cardiovascular disease risk who received Life Goals had improved physical health-related quality of life. PMID:27780336

  16. Six-month results of a biodegradable polymer and rapamycin-coating stent for coronary artery disease

    Institute of Scientific and Technical Information of China (English)

    Yuxiao ZHANG; Caiyi LU; Qiao XUE; Peng LIU; Wei YAN; Rui CHEN

    2006-01-01

    Objective To assess the safety and efficacy of a novel biodegradable polymer and rapamycin-coating stent, the EXCEL stent, in the treatment of coronary artery disease (CAD), as compared with the CypherTM stent. Methods In this prospective, non-randomized study, 60 consecutive patients with symptomatic CAD received either an EXCEL stent (n=32), or a CypherTM stent(n=28),according to their respective treatment intention. Follow-up angiography was performed at a mean of 180±40 days. The primary endpoint of the study was the occurrence of a major adverse cardiac event (MACE), including death, myocardial infarction, or target-vessel revascularization during the 6 months after stenting. The secondary end points included the in-stent late luminal loss (LLL), percentage of in-stent stenosis of the luminal diameter, and the rate of restenosis (luminal narrowing of 50 percent or more) at 6 months. Results There were no significant differences between the two groups in baseline characteristics, including the distribution of target vessel and lesion types. During the follow up period of 6 months, there were no occurrences of MACE in either group. Twenty-seven patients(84%) in the EXCEL group and 10 (36 %) in the CypherTM group underwent quantitative coronary angiography at 6 months. For these patients, no restenosis occurred, and there were no differences in the in-stent stenosis of the luminal diameter (5.98±5.52% vs 5.21 ±6.3%,P>0.05) and the LLL (-0.02±0.09 mm vs -0.01±0.07 mm, P>0.05). Conclusions Compared with the CypherTM stent, the EXCEL Stent with biodegradable polymer and rapamycin-coating showed similar efficacy in the prevention of neointimal proliferation, restenosis, and associated clinical events in CAD patients.

  17. No significant steady state surface creep along the North Anatolian Fault offshore Istanbul: Results of 6 months of seafloor acoustic ranging

    Science.gov (United States)

    Sakic, P.; Piété, H.; Ballu, V.; Royer, J.-Y.; Kopp, H.; Lange, D.; Petersen, F.; Özeren, M. S.; Ergintav, S.; Geli, L.; Henry, P.; Deschamps, A.

    2016-07-01

    The submarine Istanbul-Silivri fault segment, within 15 km of Istanbul, is the only portion of the North Anatolian Fault that has not ruptured in the last 250 years. We report first results of a seafloor acoustic ranging experiment to quantify current horizontal deformation along this segment and assess whether the segment is creeping aseismically or accumulating stress to be released in a future event. Ten transponders were installed to monitor length variations along 15 baselines. A joint least squares inversion for across-fault baseline changes, accounting for sound speed drift at each transponder, precludes fault displacement rates larger than a few millimeters per year during the 6 month observation period. Forward modeling shows that the data better fit a locked state or a very moderate surface creep—less than 6 mm/yr compared to a far-field slip rate of over 20 mm/yr—suggesting that the fault segment is currently accumulating stress.

  18. MRI monitoring of autologous hyaline cartilage grafts in the knee joint: a follow-up study over 12 months; MRT-Monitoring autologer Chondrozytentransplantate im Kniegelenk: Eine Verlaufsstudie ueber 12 Monate

    Energy Technology Data Exchange (ETDEWEB)

    Mueller-Horvat, C.; Schick, F.; Claussen, C.D.; Groenewaeller, E. [Abt. fuer Radiologische Diagnostik, Eberhard-Karls-Univ. Tuebingen (Germany)

    2004-12-01

    Purpose: To evaluate the suitability of different MR sequences for monitoring the stage of maturation of hyaline cartilage grafts in the knee joint and the early detection of complications like hypertrophy. In addition, it was analyzed whether indirect MR arthrography can indicate debonding of the graft. Materials and Methods: MRI examinations were performed in 19 patients, aged 17-43 years, with autologous transplantation of a hyaline cartilage tissue graft after knee trauma. Examination dates were prior to transplantation to localize the defect, and 6 weeks, 3, 6 and 12 months after transplantation to control morphology and maturation of the autologous graft. Standard T2- and protondensity-weighted turbo spin echo (TSE) sequences and T1-weighted spin echo (SE) sequences were used, as well as gradient echo (GRE) sequences with and without magnetization transfer (MT) prepulses. In some cases, indirect MR arthrography was performed. Results: Cartilage defect and the hyaline cartilage graft could be detected in all 19 patients. Hypertrophy of the graft could be found early in 3 patients and debonding in 1 patient. For depicting the graft a short time after surgery. T2-weighted TSE-sequences showed the best results. Six and 12 months after transplantation, spoiled 3D-GRE-sequences like FLASH3D (fast low angle shot) showed reduced artifacts due to magnetic residues from the surgery. Difference images from GRE-sequences with and without MT pulse provided high contrast between cartilage and surrounding tissue. The quantification of the MT effect showed an assimilation of the graft to the original cartilage within 12 months. Indirect MR arthrography showed subchondral contrast medium even 12 months after transplantation in 3 patients. (orig.)

  19. A field-trial of two restorative materials used with atraumatic restorative treatment in rural Turkey: 24-month results

    Directory of Open Access Journals (Sweden)

    Ertugrul Ercan

    2009-08-01

    Full Text Available OBJECTIVE: The purpose of this study was to investigate the clinical performance of high-strength glass ionomer cement (HSGIC and resin-modified glass ionomer (RMGIC in single and multiple surface carious cavities in the field conditions. MATERIAL AND METHODS: A split-mouth design, including ninety-one fillings placed on contra lateral molar pairs of 37 children, was used in permanent dentition. As filling materials, a HSGIC (Ketac Molar/3M ESPE and a RMGIC (Vitremer/ 3M ESPE were used with the Atraumatic Restorative Treatment (ART. Baseline and 6, 12 and 24-month evaluations of the fillings were made with standard-ART and USPHS criteria by two examiners with kappa values of 0.92 and 0.87 for both criteria. RESULTS: According to the USPHS criteria, the retention rates of RMGIC and HSGIC restorations were 100% and 80.9% for single surface, and 100% and 41.2% for multiple surface restorations after 24 months, respectively. Irrespective of surface number, RMGIC was significantly superior to HSGIC (p= 0.004, according to both standard-ART and USPHS criteria. CONCLUSION: The results indicate that RMGIC may be an alternative restorative technique in comparison to high-strength GIC applications in ART-field-trials. However, further clinical and field trials are needed to support this conclusion.

  20. Predicting sickness impact profile at six months after stroke: further results from the European multi-center CERISE study

    NARCIS (Netherlands)

    Stummer, C.A.; Verheyden, G.; Putman, K.; Jenni, W.; Schupp, W.; Wit, L. De

    2015-01-01

    PURPOSE: To develop prognostic models and equations for predicting participation at six months after stroke. METHODS: This European prospective cohort study recruited 532 consecutive patients from four rehabilitation centers. Participation was assessed at six months after stroke with the Sickness

  1. Solvent hold tank sample results for MCU-15-815-816-817-818-819-820 November monthly sample

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Jones, D. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-01-25

    Savannah River National Laboratory (SRNL) received one set of Solvent Hold Tank (SHT) samples (MCU-15-815-816-817-818-819-820), pulled on 11/29/2015 for analysis. The samples were inspected, combined, and analyzed for composition. Chemical analysis of the composite sample MCU-15-815-816-817-818-819-820 indicated the TiDG, Isopar™L, and MaxCalix are at nominal levels. The modifier concentration is 3% below its nominal concentration. This analysis confirms the addition of TiDG, MaxCalix, and modifier to the solvent on November 28, 2015. Based on the current monthly sample, the levels of TiDG, Isopar™L, MaxCalix, and modifier are sufficient for continuing operation but are expected to decrease with time. Periodic characterization and trimming additions to the solvent are recommended. No impurities above the 1000 ppm level were found in this solvent by the Semi-Volatile Organic Analysis (SVOA). No impurities were observed in the Hydrogen Nuclear Magnetic Resonance (HNMR). However, up to 12.5 ± 3 micrograms of mercury per gram of solvent (or 10.4 μg/mL) was detected in this sample. The solids residues found at the bottom of the p-nut vial from sample MCU-15-815 were determined to be left-over pipe residues that were flushed into the sample and they were found to have no impact on the solvent purity or on the chemical and physical properties of the solvent. The laboratory will continue to monitor the quality of the solvent in particular for any new impurities or degradation of the solvent components.

  2. Excess Body Mass Index Loss at 3 Months: A Predictive Factor of Long-Term Result after Sleeve Gastrectomy

    Directory of Open Access Journals (Sweden)

    Guillaume Philouze

    2017-01-01

    Full Text Available Introduction. Laparoscopic Sleeve Gastrectomy (SG is considered as successful if the percentage of Excess Body Mass Index Loss (% EBMIL remains constant over 50% with long-term follow-up. The aim of this study was to evaluate whether early % EBMIL was predictive of success after SG. Methods. This retrospective study included patients who had SG with two years of follow-up. Patients had follow-up appointments at 3 (M3, 6, 12, and 24 months (M24. Data as weight and Body Mass Index (BMI were collected systematically. We estimated the % EBMIL necessary to establish a correlation between M3 and M24 compared to % EBMIL speeds and calculated a limit value of % EBMIL predictive of success. Results. Data at operative time, M3, and M24 were available for 128 patients. Pearson test showed a correlation between % EBMIL at M3 and that at M24 (r=0.74;  p<0.0001. % EBMIL speed between surgery and M3 (p=0.0011 was significant but not between M3 and M24. A linear regression analysis proved that % EBMIL over 20.1% at M3 (p<0.0001 predicted a final % EBMIL over 50%. Conclusions. % EBMIL at M3 after SG is correlated with % EBMIL in the long term. % EBMIL speed was significant in the first 3 months. % EBMIL over 20.1% at M3 leads to the success of SG.

  3. The International Remote Monitoring Project -- First results of the Argentina nuclear power station field trial

    Energy Technology Data Exchange (ETDEWEB)

    Bonino, A.; Pizarro, L.; Perez, A. [Ente Nacional Regulador Nuclear, Buenos Aires (Argentina); Schoeneman, J.L.; Dupree, S.A.; Martinez, R.L. [Sandia National Labs., Albuquerque, NM (United States); Maxey, C. [Oak Ridge National Lab., TN (United States)

    1995-12-31

    As part of the International Remote Monitoring Project field trials, during the month of March, 1995 a Remote Monitoring System (RMS) was installed at the Embalse Nuclear Power Station in Embalse, Argentina. This system monitors the status of four typical Candu spent fuel dry storage silos. The monitoring equipment for each silo consists of analog temperature and gamma radiation sensors and digital motion and electronic fiber-optic seals connected to a wireless Authenticate Item Monitoring System (AIMS). All sensor data are authenticated and transmitted via RF link to Receiver Processor Units (RPU) coupled to Remote Monitoring System equipment located in a nearby IAEA/ENREN inspector office. One of these RPUs is connected to Remote Monitoring equipment capable of information transmission (via commercial telephone links) to Data Review Stations (DRS) at ENREN laboratories in Buenos Aires, Argentina, and at Sandia National Laboratories, Albuquerque, New Mexico. The other RPU is used for on-site data storage and analysis. It is anticipated that this information will soon be transmitted to a DRS at the ABACC facility in Rio de Janeiro, Brazil. During these trials site data will be collected and analyzed periodically from Buenos Aires, Albuquerque, and Rio de Janeiro. Installation detail and data analysis will be presented in this paper.

  4. Small-aperture corneal inlay in presbyopic patients with prior phakic intraocular lens implantation surgery: 3-month results

    Directory of Open Access Journals (Sweden)

    Huseynova T

    2013-08-01

    Full Text Available Tukezban Huseynova,1 Tomomi Kanamori,1 George O Waring IV,2 Minoru Tomita1,3,4 1Shinagawa LASIK Center, Tokyo, Japan; 2Medical University of South Carolina, Charleston, SC, USA; 3Wenzhou Medical College, Wenzhou, People’s Republic of China; 4Eye Can Cataract Surgery Center, Metro Manila, Philippines Abstract: We report a series of three case reports of KAMRA inlay implantation procedures in presbyopic patients with a history of prior phakic intraocular lens implantation surgery. Three-month results showed a two to five-line improvement for uncorrected near visual acuity. The absolute uncorrected near visual acuity change for case 1 was from J4 to J2, for case 2 was from J6 to J4, and for case 3 was from J10 to J5. No significant change of uncorrected distance visual acuity was observed in all three cases. Keywords: phakic intraocular lens, IOL, KAMRA, intracorneal inlay

  5. Randomized comparison of renal denervation versus intensified pharmacotherapy including spironolactone in true-resistant hypertension: six-month results from the Prague-15 study.

    Science.gov (United States)

    Rosa, Ján; Widimský, Petr; Toušek, Petr; Petrák, Ondřej; Čurila, Karol; Waldauf, Petr; Bednář, František; Zelinka, Tomáš; Holaj, Robert; Štrauch, Branislav; Šomlóová, Zuzana; Táborský, Miloš; Václavík, Jan; Kociánová, Eva; Branny, Marian; Nykl, Igor; Jiravský, Otakar; Widimský, Jiří

    2015-02-01

    This prospective, randomized, open-label multicenter trial evaluated the efficacy of catheter-based renal denervation (Symplicity, Medtronic) versus intensified pharmacological treatment including spironolactone (if tolerated) in patients with true-resistant hypertension. This was confirmed by 24-hour ambulatory blood pressure monitoring after excluding secondary hypertension and confirmation of adherence to therapy by measurement of plasma antihypertensive drug levels before enrollment. One-hundred six patients were randomized to renal denervation (n=52), or intensified pharmacological treatment (n=54) with baseline systolic blood pressure of 159±17 and 155±17 mm Hg and average number of drugs 5.1 and 5.4, respectively. A significant reduction in 24-hour average systolic blood pressure after 6 months (-8.6 [95% cofidence interval: -11.8, -5.3] mm Hg; P<0.001 in renal denervation versus -8.1 [95% cofidence interval: -12.7, -3.4] mm Hg; P=0.001 in pharmacological group) was observed, which was comparable in both groups. Similarly, a significant reduction in systolic office blood pressure (-12.4 [95% cofidence interval: -17.0, -7.8] mm Hg; P<0.001 in renal denervation versus -14.3 [95% cofidence interval: -19.7, -8.9] mm Hg; P<0.001 in pharmacological group) was present. Between-group differences in change were not significant. The average number of antihypertensive drugs used after 6 months was significantly higher in the pharmacological group (+0.3 drugs; P<0.001). A significant increase in serum creatinine and a parallel decrease of creatinine clearance were observed in the pharmacological group; between-group difference were borderline significant. The 6-month results of this study confirmed the safety of renal denervation. In conclusion, renal denervation achieved reduction of blood pressure comparable with intensified pharmacotherapy.

  6. Some Results from SAR and Optical Sensor Monitoring of China Seas

    Science.gov (United States)

    Yang, Jingsong; Lou, Xiulin; Chen, Peng; Wang, Juan; Ren, Lin; Chang, Junfang; Pan, Yufang

    2013-01-01

    As part of the final results of Dragon 2 Project Id. 5316 “Demonstrating SAR and optical sensor monitoring of Chinese Seas”, some results from SAR and optical sensor monitoring of China Seas including sea surface winds, ocean surface waves, typhoon and typhoon waves, ocean internal waves, red tides, and ships are given in this paper.

  7. [The prevention of allergic diseases with a hypoallergenic formula: a follow-up at 24 months. The preliminary results].

    Science.gov (United States)

    de Seta, L; Siani, P; Cirillo, G; Di Gruttola, M; Cimaduomo, L; Coletta, S

    1994-01-01

    One hundred-eight infants from atopic families were admitted to the study. Each had at least one first-degree relative affected by asthma or rhinitis, conjunctivitis, eczema, cow's milk protein intolerance. All infants not breast fed were hypoallergenic formula. 46 infants were breast fed, 39 were bottle fed by the ordinary formula and 23 received the hypoallergenic one. No other food was introduced up to 6 months. Cow's milk proteins, egg, poultry and fish were introduced after 6 months. All infants were followed up to 24 months. Incidence of allergic diseases up to 24 months was not significantly different among the 3 groups.

  8. Sinus Augmentation with Biomimetic Nanostructured Matrix: Tomographic, Radiological, Histological and Histomorphometrical Results after 6 Months in Humans

    Directory of Open Access Journals (Sweden)

    Antonio Scarano

    2017-08-01

    Full Text Available Background: Many bone substitutes have been applied for sinus regeneration procedures, such as autogenous bone, inorganic bovine bone, porous and resorbable hydroxyapatite, tricalcium phosphate, bioactive glass, and blood clots. The aim of the present study was a tomographic, histological and histomorphometrical evaluation in humans, of specimens retrieved from sinuses augmented with MgHA/collagen-based scaffolds, after a healing period of 6 months.Materials and Methods: Eleven healthy patients and a total of 15 sinuses were included in this study. The maxillary sinuses were filled with commercial MgHA/collagen-based scaffolds (RegenOss with a porous three-dimensional (3D structure (Fin-Ceramica Faenza S.p.A., Faenza, Italy. These grafts have a composite design, that replicate the organization of bone structure, obtained by a technique in which a specific hybrid organic–inorganic composite is spontaneously built by a biological mechanism. The CBCT scans were done before the procedure, after the surgical protocol (T1, and 6 months after sinus surgery (T2 for implantology. Bone specimens were stored in 10% formalin solution, embedded in a glycolmethacrylate resin and sectioned by a high-precision diamond disc. Histologic and histomorphometric analysis were carried out to evaluate the graft reabsorption and bone healing.Results: The mean volume after graft elevation, calculated for each of the 15 sinuses, was 2,906 mm3 in the immediate postoperative period (5–7 days, ranging from 2,148.8 to 3,146.4 mm3. In the late postoperative period (6 months it was 2,806.7 mm3, ranging from 2,010.9 to 3,008.9 mm3. The sinuses were completely healed and no residual MgHA/collagen-based scaffolds were visible. Osteoblasts appeared actively secreting bone matrix and marrow spaces contained moderate numbers of stromal cells and vascular network. Osteoblasts were observed actively secreting osteoid matrix. The tissues present in the samples were composed of 1.9

  9. 2011 Fukushima Dai-ichi nuclear power plant accident: summary of regional radioactive deposition monitoring results.

    Science.gov (United States)

    Hirose, Katsumi

    2012-09-01

    After the Great East Japan Earthquake and resulting Tsunami on March 11, 2011, serious accident of the Fukushima Dai-ichi Nuclear Power Plant has been occurred. Huge amounts of radionuclides were released in atmosphere and ocean. Japanese prefectural governments have carried out environmental radioactivity monitoring; external dose rate, radioactivity measurements in environmental samples and others. Since March 18, 2011, daily and monthly deposition samples were collected in 45 stations covering Japanese Islands and radionuclides in the deposition samples were determined. We summarize radioactive deposition data reported by Japanese Government and study the depositional behaviors of the Fukushima-derived radionuclides. The results revealed that Fukushima-derived radioactive cloud dominantly affected in the central and eastern part of Honshu-Island, although it affected all of Japanese land area and also western North Pacific. The temporal change of the Fukushima-derived (137)Cs revealed that the apparent atmospheric residence time of the Fukushima-derived (137)Cs in sites within 300 km from the Fukushima Dai-ichi NPPis about 10 d.

  10. Intravitreal bevacizumab for macular edema due to proton beam radiotherapy: Favorable results shown after eighteen months follow-up

    Directory of Open Access Journals (Sweden)

    Eleni Loukianou

    2010-05-01

    Full Text Available Eleni Loukianou, Dimitrios Brouzas, Eleni Georgopoulou, Chrysanthi Koutsandrea, Michael ApostolopoulosEye Department, University of Athens, Athens, GreecePurpose: To evaluate the safety and efficacy of intravitreal injections of bevacizumab (Avastin® as a treatment option for radiation maculopathy secondary to proton beam radiotherapy for choroidal melanoma.Case: A 61-year-old woman presented with a gradual decrease in left eye visual acuity (VA 29 months after proton beam radiotherapy for choroidal melanoma. On presentation, her best-corrected VA (BCVA was 2/10 in the left eye and the intraocular pressure was 15 mmHg. Fundoscopy revealed cystoid macular edema, intraretinal hemorrhages, epiretinal membrane in the posterior pole, and residual tumor scar with exudative retinal detachment and hard exudates in the periphery of the superotemporal quadrant. A treatment with intravitreal injections of bevacizumab (Avastin® was recommended. The injections were performed on a six-weekly basis.Results: The central retinal thickness prior to the treatment was 458 μm. After the first intravitreal injection of bevacizumab, the retinal thickness at the centre of the fovea was reduced to 322 μm. After the third injection, the central retinal thickness was 359 μm and 18 months after presentation, it reduced to 334 μm. The BCVA increased to 3/10 after the intravitreal injections of bevacizumab and remained stable during the follow-up period. The intraocular pressure was within normal range during the follow-up period.Conclusion: Bevacizumab should be regarded as a treatment option for macular edema due to proton beam radiotherapy for choroidal melanoma. By reducing the central retinal thickness, intravitreal bevacizumab can improve VA or ameliorate further decline caused by radiation maculopathy.Keywords: bevacizumab (Avastin®, choroidal melanoma, macular edema, radiation retinopathy

  11. Postpartum Hemorrhage Treated with Gelfoam Slurry Embolization Using the Superselective Technique: Immediate Results and 1-Month MRI Follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Pellerin, Olivier, E-mail: olivier.pellerin@egp.aphp.fr [Universite Paris Descartes, Sorbonne Paris Cite, Faculte de Medecine - Assistance Publique-Hopitaux de Paris - Hopital Europeen Georges-Pompidou, Paris, France, Interventional Radiology Department (France); Bats, Anne-Sophie [Universite Paris Descartes, Sorbonne Paris Cite, Faculte de Medecine - Assistance Publique-Hopitaux de Paris - Hopital Europeen Georges-Pompidou, Paris, France, Gynecologic and Oncologic Surgery Department (France); Primio, Massimiliano Di; Palomera-Ricco, Ana [Universite Paris Descartes, Sorbonne Paris Cite, Faculte de Medecine - Assistance Publique-Hopitaux de Paris - Hopital Europeen Georges-Pompidou, Paris, France, Interventional Radiology Department (France); Pinot de Villechenon, Gabrielle [Universite Paris Descartes, Sorbonne Paris Cite, Faculte de Medecine - Assistance Publique-Hopitaux de Paris - Hopital Europeen Georges-Pompidou, Paris, France, Anesthesia and Surgical Intensive Care Unit (France); and others

    2013-02-15

    To evaluate the efficacy and safety of superselective embolization of the uterine arteries in a postpartum hemorrhage. Between November 2004 and January 2011, a total of 44 consecutive women (median {+-} standard deviation age 34 {+-} 3 years, range 23-41 years) were referred to our institution for postpartum intractable hemorrhage management. All patients were embolized with a microcatheter that was placed deep into the uterine arteries upstream of the cervical arteries. The embolic agent was a mixture of contrast medium and 5 Multiplication-Sign 5 Multiplication-Sign 5 cm pieces of gelfoam (Gelita-Spon) modified into a gelatin emulsion as follows: rapid mixing through a three-way stopcock with two 2.5-ml syringes. A 1-ml syringe was used for injection. One month after embolization, all patients underwent magnetic resonance imaging and clinical examination. Technical and clinical success was obtained in all cases. Thirty-five patients experienced bleeding related to poor retraction of the uterus, 7 patients because of a tear of the cervix and 2 because of a vaginal hematoma. Pre- and postembolization red blood cell transfusions were (mean {+-} standard deviation [SD]) 6 {+-} 1.2 (range 3-8) U and 2 {+-} 0.7 (range 2-4) U, respectively. One-month magnetic resonance imaging follow-up revealed no sign of ischemic myometrium or necrosis, and no instances of uterine rupture and no pelvic vein thrombosis. Incidental findings included two small intramyometrial hematic collections. All uterine arteries were patent via magnetic resonance angiography. Seventeen patients had concomitant fibroids, all of which appeared hypovascular. This technique permits good, safe clinical results with no marked damage to the uterine arteries or the uterus itself.

  12. Multiwavelength observations of 3C 454.3. III. Eighteen months of AGILE monitoring of the "Crazy Diamond"

    CERN Document Server

    Vercellone, S; Vittorini, V; Donnarumma, I; Pucella, G; Tavani, M; Ferrari, A; Raiteri, C M; Villata, M; Romano, P; Krimm, H; Tiengo, A; Chen, A W; Giovannini, G; Venturi, T; Giroletti, M; Kovalev, Y Y; Sokolovsky, K; Pushkarev, A B; Lister, M L; Argan, A; Barbiellini, G; Bulgarelli, A; Caraveo, P; Cattaneo, P W; Cocco, V; Costa, E; Del Monte, E; De Paris, G; Di Cocco, G; Evangelista, Y; Feroci, M; Fiorini, M; Fornari, F; Froysland, T; Fuschino, F; Galli, M; Gianotti, F; Labanti, C; Lapshov, I; Lazzarotto, F; Lipari, P; Longo, F; Giuliani, A; Marisaldi, M; Mereghetti, S; Morselli, A; Pellizzoni, A; Pacciani, L; Perotti, F; Piano, G; Picozza, P; Pilia, M; Prest, M; Rapisarda, M; Rappoldi, A; Sabatini, S; Soffitta, P; Striani, E; Trifoglio, M; Trois, A; Vallazza, E; Zambra, A; Zanello, D; Pittori, C; Verrecchia, F; Santolamazza, P; Giommi, P; Colafrancesco, S; Salotti, L; Agudo, I; Aller, H D; Aller, M F; Arkharov, A A; Bach, U; Bachev, R; Beltrame, P; Benitez, E; Boettcher, M; Buemi, C S; Calcidese, P; Capezzali, D; Carosati, D; Chen, W P; Da Rio, D; Di Paola, A; Dolci, M; Dultzin, D; Forne, E; Gomez, J L; Gurwell, M A; Hagen-Thorn, V A; Halkola, A; Heidt, J; Hiriart, D; Hovatta, T; Hsiao, H Y; Jorstad, S G; Kimeridze, G; Konstantinova, T S; Kopatskaya, E N; Koptelova, E; Kurtanidze, O; Lahteenmaki, A; Larionov, V M; Leto, P; Ligustri, R; Lindfors, E; Lopez, J M; Marscher, A P; Mujica, R; Nikolashvili, M; Nilsson, K

    2010-01-01

    We report on 18 months of multiwavelength observations of the blazar 3C 454.3 (Crazy Diamond) carried out in July 2007-January 2009. We show the results of the AGILE campaigns which took place on May-June 2008, July-August 2008, and October 2008-January 2009. During the May 2008-January 2009 period, the source average flux was highly variable, from an average gamma-ray flux F(E>100MeV) > 200E-8 ph/cm2/s in May-June 2008, to F(E>100MeV)~80E-8 ph/cm2/s in October 2008-January 2009. The average gamma-ray spectrum between 100 MeV and 1 GeV can be fit by a simple power law (Gamma_GRID ~ 2.0 to 2.2). Only 3-sigma upper limits can be derived in the 20-60 keV energy band with Super-AGILE. During July-August 2007 and May-June 2008, RXTE measured a flux of F(3-20 keV)= 8.4E-11 erg/cm2/s, and F(3-20 keV)=4.5E-11 erg/cm2/s, respectively and a constant photon index Gamma_PCA=1.65. Swift/XRT observations were carried out during all AGILE campaigns, obtaining a F(2-10 keV)=(0.9-7.5)E-11 erg/cm2/s and a photon index Gamma_XR...

  13. Persistent quality of life impairments in differentiated thyroid cancer patients: results from a monitoring programme

    Energy Technology Data Exchange (ETDEWEB)

    Gamper, Eva-Maria [Medical University Innsbruck, Department for Nuclear Medicine, Innsbruck (Austria); Medical University Innsbruck, Department for Psychiatry and Psychotherapy, Innsbruck (Austria); Wintner, Lisa M.; Holzner, Bernhard [Medical University Innsbruck, Department for Psychiatry and Psychotherapy, Innsbruck (Austria); Rodrigues, Margarida; Buxbaum, Sabine; Nilica, Bernhard; Virgolini, Irene [Medical University Innsbruck, Department for Nuclear Medicine, Innsbruck (Austria); Singer, Susanne [University of Mainz, Institute of Medical Biostatistics, Epidemiology, and Informatics, Mainz (Germany); Giesinger, Johannes M. [Netherlands Cancer Institute, Amsterdam (Netherlands)

    2015-07-15

    Health-related quality of life (HRQOL) in differentiated thyroid cancer (DTC) research has so far received little attention and available results are conflicting. We studied the HRQOL of radioiodine-naive DTC patients in comparison with the general population (GP), investigated the course of HRQOL up to 30 months after radioiodine remnant ablation (RAA) and sought to identify patient characteristics associated with HRQOL. We analysed data from routine HRQOL monitoring at a nuclear medicine department. Between 2005 and 2013, a total of 439 thyroid cancer patients (all histologies) completed the EORTC Quality of Life Questionnaire Core-30 (QLQ-C30) at least once during their treatment at the department. We compared patients' baseline HRQOL scores before RAA with scores from age-matched and sex-matched controls from the Austrian GP. We then determined the course of HRQOL over the 30 months after RAA and assessed the impact of the following clinical variables on HRQOL: method of thyroid-stimulating hormone (TSH) stimulation, histology (papillary vs. follicular) and disease stage. A total of 284 patients (mean age 48.3 years, SD 15.0 years; 71.6 % women; 80.7 % papillary type) with a baseline HRQOL assessment before RAA were available. We found clinically meaningful differences in the detriment in patients on almost all domains. These were largest for fatigue (23 points) and role functioning (25 points). Data from 241 patients (mean age 48.6 years, SD 15.9 years; 68.9 % women; 76.3 % papillary type) were included in the longitudinal analysis. Investigating the course of HRQOL, a significant improvement over time was found for role and emotional functioning, fatigue, pain, and dyspnoea. A range of HRQOL scores were improved in patients with exogenous TSH stimulation, but some scores both in patients with exogenous TSH stimulation and in those followed for 30 months, especially fatigue and role functioning, did not reach levels in the GP sample. Our results show that

  14. Results of the marine biota monitoring during drilling activity on Campos Basin, Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Petta, Claudia Brigagao de; Bastos, Fabio; Danielski, Monica; Ferreira, Mariana; Gama, Mariana; Coelho, Ana Paula Athanazio; Maia, Decio [Aecom do Brasil Ltda, Rio de Janeiro, RJ (Brazil)

    2012-07-01

    The Environmental Monitoring Project (PMA) aims to report environmental changes arising from drilling activity, in relation to the marine fauna. This project can also help in the monitoring of accidental spills. Since the professionals spend six hours of the day monitoring the ocean around the rigs, they can locate and identify oil stains, notify the responsible onboard, and also help in the monitoring of the oil stain. Such Project has been developed onboard a drilling unit working in Campos Basin. The results presented here were collected during the drilling activity in Bijupira and Salema fields, by Shell Brasil Petroleo Ltda, from July 13th to October 8th, 2011.

  15. Results of Vapor Space Monitoring of Flammable Gas Watch List Tanks

    Energy Technology Data Exchange (ETDEWEB)

    MCCAIN, D.J.

    2000-09-27

    This report documents the measurement of headspace gas concentrations and monitoring results from the Hanford tanks that have continuous flammable gas monitoring. The systems used to monitor the tanks are Standard Hydrogen Monitoring Systems. Further characterization of the tank off-gases was done with Gas Characterization systems and vapor grab samples. The background concentrations of all tanks are below the action level of 6250 ppm. Other information which can be derived from the measurements (such as generation rate, released rate, and ventilation rate) is also discussed.

  16. Preventing Compulsory Admission to Psychiatric Inpatient Care: Perceived Coercion, Empowerment, and Self-Reported Mental Health Functioning after 12 Months of Preventive Monitoring.

    Science.gov (United States)

    Lay, Barbara; Drack, Thekla; Bleiker, Marco; Lengler, Silke; Blank, Christina; Rössler, Wulf

    2015-01-01

    To evaluate the effects of a preventive monitoring program targeted to reduce compulsory rehospitalization and perceived coercion in patients with severe mental disorder. We analyze patient outcomes in terms of perceived coercion, empowerment, and self-reported mental health functioning at 12 months. The program consists of individualized psychoeducation, crisis cards and, after discharge from the psychiatric hospital, a 24-month preventive monitoring. In total, 238 psychiatric inpatients who had had compulsory admission(s) during the past 24 months were included in the trial. T1-assessment 12 months after baseline was achieved for 182 patients. Study participants reported lower levels of perceived coercion, negative pressures, and process exclusion, a higher level of optimism, and a lesser degree of distress due to symptoms, interpersonal relations, and social role functioning (significant time effects). However, improvements were not confined to the intervention group, but seen also in the treatment-as-usual group (no significant group or interaction effects). Altered perceptions were linked to older age, shorter illness duration, female sex, non-psychotic disorder, and compulsory hospitalization not due to risk of harm to others. Our findings suggest that changes in the subjective perspective were fueled primarily by participation in this study rather than by having received the specific intervention. The study contributes to a better understanding of the interaction between "objective" measures (compulsory readmissions) and patients' perceptions and highlights the need for treatment approaches promoting empowerment in individuals with a history of involuntary psychiatric hospitalizations.

  17. Evaluation of the Nasal Surgical Questionnaire for Monitoring Results of Septoplasty

    Directory of Open Access Journals (Sweden)

    Rolf Haye

    2015-01-01

    Full Text Available Monitoring the results of surgery is important. The otorhinolaryngology department of our hospital currently uses preoperative and postoperative versions of the Nasal Surgical Questionnaire (NSQ for continuous evaluation of nasal septoplasty. In this study, 55 patients undergoing septoplasty answered the preoperative version twice to assess the NSQ’s test-retest precision, and 75 patients answered the preoperative questionnaire before and the postoperative one 6 months after surgery to evaluate the NSQ’s ability to detect change in symptoms following surgery. Both the pre- and postoperative versions of the NSQ use separate visual analogue scales (VAS to assess nasal obstruction during the day, at night, and during exercise. Other nasal symptoms are graded as secondary outcomes using 4-point Likert scales. The mean VAS scores for the two preoperative obstruction ratings were not significantly different. The scores were significantly higher than in a normal population. There were also significant differences between preoperative and postoperative ratings. The mean pre- and postoperative scores at night for those who reported complete improvement were 66.1 and 8.4, substantial improvement 74.5 and 24.2, and no improvement 83.3 and 76.4. The NSQ reliably assesses nasal symptoms in patients and may be useful for both short and long term prospective studies of septoplasty.

  18. INFLUENCE OF DIFFERENT TYPES OF NUTRITION ON PHYSICAL AND NEUROPSYCHICAL DEVELOPMENT OF INFANTS: RESULTS OF 12-MONTHS OBSERVATION

    Directory of Open Access Journals (Sweden)

    T. I. Legon’kova

    2011-01-01

    Full Text Available The basic ingredient of normal nutrition in infants is breast milk. If breast feeding is impossible the choice of artificial feeding formula should be made taking into account the qualities of formula which must be extremely close to that ones of breast milk. Objectives: to evaluate of state of health of infants having breast and artificial feeding. Methods: effectiveness and tolerance to adopted formula «Nutrilon Comfort» compared to standard milk formula and breast milk were analyzed. Dynamics of physical and neuro-psychical development of children was observed during 12 months. The cases of infectious diseases and tolerance to artificial feeding formulas were estimated. Results: prolonged observation of children from the group of adopted formula with immunomodulatory factors (long-chain polyunsaturated fatty acids and prebiotics showed its complex action (influence on physical, neuro-psychical development and infectious morbidity is similar to that one of breast feeding. Acute respiratory infections and atopic dermatitis in children having breast feeding and adopted formula developed rarely than in children from group of standard formula (p < 0.05. Conclusion: nutrition with «Nutrilon Comfort» formula in cases when breast feeding is impossible allows child’s development similar to children with breast feeding.

  19. Aespoe Pillar Stability Experiment. Final experiment design, monitoring results and observations

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Christer [Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden); Eng, Anders [Acuo Engineering AB, Linkoeping (Sweden)

    2005-12-15

    The field part of the Aespoe Pillar Stability Experiment at the Aespoe Hard Rock Laboratory (HRL) was finished in 2004. The experiment was designed to induce and monitor the process of brittle failure, spalling, in a fractured rock mass under controlled conditions. The field part was successfully conducted and a large data set was obtained. This report presents the final design of the experiment, the results of the monitoring, and the observations made during the spalling process and when the spalled rock was removed. When heating of the rock was initiated the rock responded quickly. After only a few days the spalling process was activated in the notch, as indicated by the acoustic emission system, and shortly thereafter displacement readings were recorded. Contraction (radial expansion) of the rock was recorded by several instruments before the notch reached the instrument levels. This contraction is probably the result of a 3D re-distribution of the stresses. The temperature increase in the system was both slower and reached a steady state much earlier than predicted by the numerical models. The propagation of the notch was therefore halted after approximately one month of heating. The power to the electrical heaters was therefore doubled. Spalling then started up again, and in one month's time it had propagated to a depth of approximately five metres in the hole. A second steady state was now reached, but this time the heater power was kept constant for a while to let the rock settle before the confinement pressure was reduced from 700 kPa to 0 in decrements of 50 kPa. The rock mass response to the pressure drop was very limited until the pressure was lowered to approximately 200 kPa (the atmospheric pressure is not included in the given pressure values). Large displacements and a high acoustic emission hit frequency were then measured in the open hole. After the de-pressurization of the confined hole, the heaters were left on for approximately one week

  20. Holmium Laser Enucleation of the Prostate versus Laparoscopic Transcapsular Prostatectomy: Perioperative Results and Three-Month Follow-Up.

    Science.gov (United States)

    Baldini, Arnaud; Fassi-Fehri, Hakim; Duarte, Ricardo C; Crouzet, Sebastien; Ecochard, René; Abid, Nadia; Martin, Xavier; Badet, Lionel; Colombel, Marc

    2017-07-01

    Symptomatic benign prostatic hypertrophy greater than 70 cc used to be treated by invasive procedures. Holmium laser enucleation of prostate (HoLEP) and laparoscopic transcapsular prostatectomy (LTP) are two techniques whose efficacy has been demonstrated compared to standard onesmore invasive standard procedures. The objective was to evaluate and compare perioperative results from these two techniques for the treatment of benign prostatic hypertrophy greater than 70 cc. This was a non-randomized retrospective study comparing the HoLEP technique with LTP. From January 2012 to January 2015, 39 patients had HoLEP and 28 had LTP. Perioperative outcomes, complications, and functional results at 3 months were compared. A chi-2 squared test and Student's t test were used for statistical analysis. In multivariate analysis, there was a statistically significant difference in favor of HoLEP for the duration of catheterization (1.9 vs. 3.7 days; p = 0.004) and the average length of stay (2.8 vs. 4.0 days, p = 0.010). There was a trend towards a greater decrease in postoperative hemoglobin levels in LTP (138 vs. 218 g/l; p = 0.082), which was statistically significant in univariate analysis (p = 0.033). Other endpoints were not significant, particularly the enucleated prostate volume compared to the total prostate volume (61.8 vs. 68.4%; p = 0.319) and postoperative complications. There was no increased morbidity for LTP compared to the HoLEP technique. However, the HoLEP technique appeared to be a less invasive technique, reducing the duration of catheterization, blood loss, and the average length of stay while maintaining good efficacy for the enucleated prostate volume.

  1. Technical results of Y-12/IAEA field trial of remote monitoring system

    Energy Technology Data Exchange (ETDEWEB)

    Corbell, B.H. [Sandia National Labs., Albuquerque, NM (United States); Whitaker, J.M. [Lockheed Martin Energy Systems, Inc., Oak Ridge, TN (United States); Welch, J. [Aquila Technologies Group, Albuquerque, NM (United States)] [and others

    1997-08-01

    A Remote Monitoring System (RMS) field trial has been conducted with the International Atomic Energy Agency (IAEA) on highly enriched uranium materials in a vault at the Oak Ridge Y-12 Plant. The RMS included a variety of Sandia, Oak Ridge, and Aquila sensor technologies which provide containment seals, video monitoring, radiation asset measurements, and container identification data to the on-site DAS (Data Acquisition System) by way of radio-frequency and Echelon LonWorks networks. The accumulated safeguards information was transmitted to the IAEA via satellite (COMSAT/RSI) and international telephone lines. The technologies tested in the remote monitoring environment are the RadCouple, RadSiP, and SmartShelf sensors from the ORSENS (Oak Ridge Sensors for Enhancing Nuclear Safeguards) technologies; the AIMS (Authenticated Item Monitoring System) motion sensor (AMS), AIMS fiber-optic seal (AFOS), ICAM (Image Compression and Authentication Module) video surveillance system, DAS (Data Acquisition System), and DIRS (Data and Image Review Station) from Sandia; and the AssetLAN identification tag, VACOSS-S seal, and Gemini digital surveillance system from Aquila. The field trial was conducted from October 1996 through May 1997. Tests were conducted during the monthly IAEA Interim Inventory Verification (IIV) inspections for evaluation of the equipment. Experience gained through the field trials will allow the technologies to be applied to various monitoring scenarios.

  2. Getting Results in Housing: A Framework for Monitoring Results in Housing Projects: Using Measurable Indicators

    OpenAIRE

    Shlomo Angel; Michael Jacobs

    2006-01-01

    The aim of this paper is to help project teams develop results indicators for housing projects. These indicators are intended, primarily, as an instrument for managing projects and should help staff in the country offices, in headquarters and in executing agencies to identify the components of a project that are working as intended, and the ones that may need attention to keep the project on track. Additionally, the indicators can provide a foundation for project evaluations, at the mid-term ...

  3. Long-Term Respiratory Muscle Endurance Training in Patients with Myasthenia Gravis: First Results after Four Months of Training

    Directory of Open Access Journals (Sweden)

    Beate Rassler

    2011-01-01

    Full Text Available Myasthenia gravis (MG is characterized by reduced muscle endurance and is often accompanied by respiratory complications. Improvement of respiratory function is therefore an important objective in MG therapy. A previous study demonstrated that respiratory muscle endurance training (RMET over four weeks increased respiratory muscle endurance of MG patients to about 200% of baseline. The purpose of the present study was to establish an appropriate maintenance training and to test its effects over four months. Ten patients with mild to moderate MG participated in this study. During the first month, they performed five training sessions per week. For the following 3 months, training frequency was reduced to five sessions per two weeks. Myasthenia score, lung function, and respiratory endurance were determined prior to training, after the first month, and after 4 months. Myasthenia score improved from 0.71±0.1 to 0.56±0.1 (P=0.007. Respiratory endurance time increased from 6.1±0.8 to 20.3±3.0 min (P<0.001. In conclusion, this RMET maintenance program is feasible and is significantly beneficial for MG patients.

  4. Clinical and radiological results of fixation of acromioclavicular joint dislocation by hook plates retained for more than five months.

    Science.gov (United States)

    Jafary, Dawood; Keihan Shokouh, Hassan; Najd Mazhar, Farid; Shariat Zadeh, Human; Mochtary, Tahmineh

    2014-04-01

    Hook plates are used to treat acromioclavicular joint dislocations. Our study took into consideration the patients' outcome following treatment with clavicular hook plates retained for more than five months. Our aim was to assess the response to treatment of acromioclavicular joint dislocation by clavicular hook plate when retained for more than five months. We treated 24 patients who had acromioclavicular joint dislocation with a clavicular hook plate between 2008 and 2012 at our hospital. We did not repair the coracoclavicular ligament. In all patients, the plate remained more than five months because they did not come back at the recommended time for removal of their plates. The follow-up period ranged from five to thirty three months with a mean of nineteen months. The main complication was osteolysis that was seen in two patients. The mean constant score was 94.5 ± 8.77 out of 100 with a range between 70 and 100. Our study showed that the use of clavicular hook plates was a good treatment option for acromioclavicular joint dislocation. However, scores were lower in case of prolonged presence of plates.

  5. Environmental surveillance monitoring in the Alligator Rivers Region. Report for the six months period ending 30 September 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report outlines the activities of the Northern Territory Supervising Authorities in meeting their responsibilities for environmental management and surveillance, occupational safety, relating to uranium mining and environment protection in the Alligator Rivers Region. Environmental monitoring was carried out at the Nabarlek Mine, which site has now been rehabilitated and revegetated, and at Ranger, the only mine currently operating in the region. Other uranium projects such as Jabiluka and Koongarra have been delayed due to the former Commonwealth Government`s `three mines policy`. 4 tabs., 10 figs.

  6. Pit and Fissure Sealants with Different Materials: Resin Based x Glass Ionomer Cement – Results after Six Months

    Directory of Open Access Journals (Sweden)

    Priscilla Santana Pinto Gonçalves

    2016-01-01

    Full Text Available Objective: To compare the retention and superficial characteristics between a new resin-modified glass ionomer sealant and resin sealant. In addition, the teeth sealed were compared to partially erupted first molars (control group without sealing in relation to the incidence of dental caries. Material and Methods: Initially, 31 children aged 6-8 years participated in this study. The study children showed caries history, but had at least two healthy first molars. A total of 114 teeth were randomly divided into three groups: Clinpro (n=36, Fluroshield (n=38, and control (n=40. The two sealants were applied under relative isolation after previous prophylaxis and enamel etching with phosphoric acid 35% (15s. Clinical evaluation was performed by two calibrated examiners. They evaluated the retention and surface characteristics of the occlusal surface. Results: Fluroshield® showed significantly greater retention than ClinproTM Varnish® XT (p=0.002. However, the performance analysis of the success and failure of retention presented no significant difference between the materials (p=0.141. Concerning to the surface characteristics, Fluroshield performed better than Clinpro after analyzing the marginal deterioration, marginal discoloration, and superficial discoloration (p<0.05. The surface texture of the materials under study was similar (p=0.071. Sealed groups (Clinpro=Fluroshield showed similar performance in the prevention of dental caries, which was significantly lower than that of control group (p=0.001. Conclusion: Both sealants, Fluroshield® and Clinpro TM Varnish® XT were effective in preventing caries lesion within 6 months, although Fluroshield sealant showed better clinical retention.

  7. Results of the 1986 seabird monitoring program at Cape Lisburne, Alaska

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report covers the results of the 1986 seabird monitoring program at Cape Lisburne, Alaska. Objectives of this reports includes determining reproductive success,...

  8. Macular epiretinal brachytherapy in treated age-related macular degeneration: MERITAGE study: twelve-month safety and efficacy results.

    Science.gov (United States)

    Dugel, Pravin U; Petrarca, Robert; Bennett, Michael; Barak, Adiel; Weinberger, Dov; Nau, Jeffrey; Jackson, Timothy L

    2012-07-01

    To evaluate the safety and efficacy of epimacular brachytherapy (EMB) for the treatment of chronic, active, neovascular age-related macular degeneration (AMD). Prospective, multicenter, interventional, noncontrolled clinical trial. Fifty-three eyes of 53 participants with neovascular AMD requiring frequent anti-vascular endothelial growth factor (VEGF) retreatment. Participants underwent pars plana vitrectomy with a single 24-Gy dose of EMB delivered using an intraocular, handheld cannula containing a strontium 90/yttrium 90 source positioned over the active lesion. Participants were retreated with ranibizumab administered monthly as needed, using predefined retreatment criteria. Optical coherence tomography (OCT) was undertaken monthly, with images assessed by an independent reading center. Coprimary outcomes at 12 months were proportion of participants with stable vision (losing brachytherapy produces stable visual acuity in most participants with previously treated, active disease. Epimacular brachytherapy may reduce the need for frequent anti-VEGF retreatment. Copyright © 2012 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  9. Ablation for atrial fibrillation during mitral valve surgery: 1-year results through continuous subcutaneous monitoring.

    Science.gov (United States)

    Bogachev-Prokophiev, Alexandr; Zheleznev, Sergey; Romanov, Alexander; Pokushalov, Evgeny; Pivkin, Alexey; Corbucci, Giorgio; Karaskov, Alexander

    2012-07-01

    Continuous monitoring of cardiac rhythm may play an important role in measuring the true symptomatic/asymptomatic atrial fibrillation (AF) burden and improve the management of anti-arrhythmic and anti-thrombotic therapies. Forty-seven patients with mitral valve disease and longstanding persistent AF (LSPAF) underwent a left atrial maze procedure with bipolar radiofrequency and valve surgery. The follow-up data recorded by an implanted loop recorder were analysed after 3, 6 and 12 months. On discharge, 40 (85.1%) patients were in stable sinus rhythm, as documented by in-office electrocardiography (ECG), 4 (8.5%) were in pacemaker rhythm and 3 (6.4%) were in AF. One (2.1%) patient died after 7 months. On 12-month follow-up examination, 30 (65.2%) patients had an AF burden 0.5%. Two (4.3%) patients with AF recurrences were completely asymptomatic. Among the symptomatic events stored by the patients, only 27.6% was confirmed as genuine AF recurrences according to the concomitant ECG recorded by the implanted loop recorder. A concomitant bipolar maze procedure during mitral valve surgery is effective in treating AF, as proved by detailed 1-year continuous monitoring.

  10. Hypofractionated stereotactic radiotherapy of acoustic neuroma. Volume changes and hearing results after 89-month median follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Kranzinger, Manfred; Fastner, Gerd [Paracelsus Medical University Clinics (PMU), University Clinic of Radiotherapy and Radio-Oncology, Salzburg County Hospital, Salzburg (Austria); Zehentmayr, Franz; Sedlmayer, Felix [Paracelsus Medical University Clinics (PMU), University Clinic of Radiotherapy and Radio-Oncology, Salzburg County Hospital, Salzburg (Austria); Salzburg County Hospital, Paracelsus Medical University Clinics, radART - Institute for Research and Development on Advanced Radiation Technologies, Salzburg (Austria); Oberascher, Gerhard [Paracelsus Medical University Clinics (PMU), University Clinic of Ear, Nose and Throat Diseases, Salzburg County Hospital, Salzburg (Austria); Merz, Florian; Rahim, Hassan [Salzburg County Hospital, Paracelsus Medical University Clinics, Medical Radiation Protection Unit, Salzburg (Austria); Nairz, Olaf [Clinic Bad Trissl, Oberaudorf (Germany)

    2014-09-15

    The goal of this work was to evaluate toxicity and local control following hypofractionated stereotactic radiation treatment with special focus on changes in tumor volume and hearing capacity. In all, 29 patients with unilateral acoustic neuroma were treated between 2001 and 2007 within a prospective radiation protocol (7 x 4 Gy ICRU dose). Median tumor volume was 0.9 ml. Follow-up started at 6 months and was repeated annually with MRI volumetry and audiometry. Hearing preservation was defined as preservation of Class A/B hearing according to the guidelines of the American Academy of Otolaryngology (1995). No patient had any intervention after a median imaging follow-up of 89.5 months, one patient showed radiological progression. Transient increase of tumor volume developed in 17/29 patients, whereas 22/29 patients (75.9 %) presented with a volume reduction at last follow-up. A total of 21 patients were eligible for hearing evaluation. Mean pure tone average (PTA) deteriorated from 39.3 to 65.9 dB and mean speech discrimination score (SDS) dropped from 74.3 to 38.1 %. The 5-year actuarial Class A/B hearing preservation rate was 50.0 ± 14.4 %. Radiation increases only minimally, if at all, the hearing deterioration which emerges by observation alone. Presbyacusis is not responsible for this deterioration. Transient tumor enlargement is common. Today radiation of small- and medium-sized acoustic neuroma can be performed with different highly conformal techniques as fractionated treatment or single low-dose radiosurgery with equal results regarding tumor control, hearing preservation, and side effects. Hypofractionation is more comfortable for the patient than conventional regimens and represents a serious alternative to frameless radiosurgery. (orig.) [German] Ziel der Studie war die Evaluierung der Toxizitaet und der lokalen Tumorkontrolle einer hypofraktionierten stereotaktischen Bestrahlung mit besonderem Augenmerk auf Veraenderungen von Tumorvolumen und

  11. Ranibizumab versus aflibercept for macular edema due to central retinal vein occlusion: 18-month results in real-life data.

    Science.gov (United States)

    Chatziralli, Irini; Theodossiadis, George; Moschos, Marilita M; Mitropoulos, Panagiotis; Theodossiadis, Panagiotis

    2017-06-01

    The objective of this study was to compare the anatomical and functional outcomes of ranibizumab versus aflibercept for the treatment of macular edema due to central retinal vein occlusion (CRVO) in routine clinical practice. Participants in this observational study included 62 treatment-naïve patients with CRVO who received intravitreal injections of either ranibizumab or aflibercept. The demographic data, best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography (SD-OCT) characteristics were evaluated at baseline and at months 1, 2, 3, 6, 12 and 18 post-treatment. At month 18, the mean BCVA of ranibizumab-treated eyes increased 7.9 letters, compared to 7.4 letters for eyes receiving aflibercept, with a similar number of injections. There was no statistically significant difference between the two groups in letters or in central subfield thickness at month 18. At the end of the follow-up, 50% of patients in the ranibizumab group and 42.9% in the aflibercept group showed complete resolution of macular edema. Ranibizumab and aflibercept demonstrated similar anatomical and functional outcomes over 18-month follow-up in patients with macular edema due to CRVO, with a similar number of injections.

  12. A UV-Raman spectrometry method for quality control of anticancer preparations: Results after 18 months of implementation in hospital pharmacy.

    Science.gov (United States)

    Nardella, Flore; Beck, Morgane; Collart-Dutilleul, Pierre; Becker, Guillaume; Boulanger, Coralie; Perello, Laurent; Gairard-Dory, Anne; Gourieux, Bénédicte; Ubeaud-Séquier, Geneviève

    2016-02-29

    In France, chemotherapy preparation units of hospital pharmacy compound cytotoxic infusion bags adapted to each patient. The narrow therapeutic index of these preparations led us to implement qualitative and quantitative control for patients' safety. To this aim, we calibrated an equipment combining UV-vis spectrometry and Raman spectroscopy (QC Prep+) and monitored 14 different molecule-solvent combinations over a 18 months period. This rapid and specific method allowed the qualitative and quantitative analysis of 1 mL sample tests in less than 2 min. On 5742 anticancer preparations, we obtained accepted results with more than 99.4% solvent identification, 99.6% drug identification and only 1.52% of preparations not matching quantitative specifications (±15% of theoretical concentration). This quantitative control enabled us to pinpoint some critical points of production for two of the most common preparations. We thus updated the procedures of reconstitution and preparation, increasing the quality of final product. UV-Raman spectrometry is thus an effective tool to control chemotherapy infusions and to improve good practices of preparation. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Two-dimensional monthly average ozone balance from limb infrared monitor of the stratosphere and stratospheric and mesospheric sounder data

    Science.gov (United States)

    Jackman, C. H.; Stolarski, R. S.; Kaye, J. A.

    1986-01-01

    For many years, atmospheric scientists have been concerned with the balance of ozone production and loss terms in the upper stratosphere. Crutzen and Schmailzl (1983) found that the ozone loss was higher than the ozone production in the upper stratosphere. In the present investigation, previous studies are used as a basis in the conduction of a two-dimensional calculation of the production and loss of ozone. The monthly and zonally averaged loss and production rates for ozone are computed using recent Nimbus 7 satellite measurements of stratospheric constituents and accepted reaction and photodissociation rates. It is found that ozone has a loss rate which is about 40-60 percent higher than the production in the photochemical region.

  14. Optimal medical therapy for secondary prevention after an acute coronary syndrome: 18-month follow-up results at a tertiary teaching hospital in South Korea

    Directory of Open Access Journals (Sweden)

    Byeon HJ

    2016-02-01

    Full Text Available Hee Ja Byeon,1,* Young-Mo Yang,2,* Eun Joo Choi21Department of Pharmacy, Chosun University Hospital, 2Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju, South Korea*These authors contributed equally to this workBackground: Acute coronary syndrome (ACS is a fatal cardiovascular disease caused by atherosclerotic plaque erosion or rupture and formation of coronary thrombus. The latest guidelines for ACS recommend the combined drug regimen, comprising aspirin, P2Y12 inhibitor, angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker, β-blocker, and statin, at discharge after ACS treatment to reduce recurrent ischemic cardiovascular events. This study aimed to examine prescription patterns of secondary prevention drugs in Korean patients with ACS after hospital discharge, to access the appropriateness of secondary prevention drug therapy for ACS, and to evaluate whether to persistently use discharge medications for 18 months.Methods: This study was retrospectively conducted with the patients who were discharged from the tertiary hospital, located in South Korea, after ACS treatment between September 2009 and August 2013. Data were collected through electronic medical record.Results: Among 3,676 patients during the study period, 494 were selected based on inclusion and exclusion criteria. The regimen of aspirin + clopidogrel + β-blocker + angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker + statin was prescribed to 374 (75.71% patients with ACS at discharge. Specifically, this regimen was used in 177 (69.69% unstable angina patients, 44 (70.97% non-ST-segment elevation myocardial infarction patients, and 153 (85.96% ST-segment elevation myocardial infarction patients. Compared with the number of ACS patients with all five guideline-recommended drugs at discharge, the number of ACS patients using them 12 (n=169, 34.21% and 18 (n=105, 21.26% months after discharge tended to be gradually

  15. Beach monitoring using Unmanned Aerial Vehicles: results of a multi-temporal study

    Science.gov (United States)

    Casella, Elisa; Rovere, Alessio; Casella, Marco; Pedroncini, Andrea; Ferrari, Marco; Vacchi, Matteo; Firpo, Marco

    2015-04-01

    The application of Unmanned Aerial Vehicles and photogrammetry techniques in earth sciences is flourishing. In this study, we show how we applied small Unmanned Aerial Vehicles to the study of topographic changes of a beach in Italy, NW Mediterranean Sea. We surveyed the same stretch of coastline three times in 5 months, obtaining ortophotos and digital elevation models of the beach using a structure from motion approach. We then calculated the difference in beach topography between each time step, and we related topography changes to both human and natural modifications of the beach morphology that can be inferred from aerial photos or wave data. We conclude that small drones have the potential to open new possibilities for beach monitoring studies, and can be successfully employed for multi-temporal monitoring studies at relatively low cost.

  16. Twelve Months of Air Quality Monitoring at Ash Meadows National Wildlife Refuge, Southwestern Rural Nevada, U.S.A (EMSI April 2007)

    Energy Technology Data Exchange (ETDEWEB)

    Engelbrecht, Johann P; Shafer, David S; Campbell, Dave; Campbell, Scott; McCurdy, Greg; Kohl, Steven D; Nikolich, George; Sheetz, Larry

    2011-08-01

    The one year of air quality monitoring data collected at the Ash Meadows National Wildlife Refuge (NWR) was the final part of the air quality "Scoping Studies" for the Environmental Monitoring Systems Initiative (EMSI) in southern and central Nevada. The objective of monitoring at Ash Meadows was to examine aerosol and meteorological data, seasonal trends in aerosol and meteorological parameters as well as to examine evidence for long distance transport of some constituents. The 9,307 hectare refuge supports more than 50 springs and 24 endemic species, including the only population of the federally listed endangered Devil’s Hole pupfish (Cyprinodon diabolis) (U.S. Fish and Wildlife Service, 1990). Ash Meadows NWR is located in a Class II air quality area, and the aerosol measurements collected with this study are compared to those of Interagency Monitoring of Protected Visual Environments (IMPROVE) sites. Measurements taken at Ash Meadows NWR over a period of 12 months provide new baseline air quality and meteorological information for rural southwestern Nevada, specifically Nye County and the Amargosa Valley.

  17. ENVIRONMENTAL RADIATION MONITORING IN THE CHERNOBYL EXCLUSION ZONE - HISTORY AND RESULTS 25 YEARS AFTER

    Energy Technology Data Exchange (ETDEWEB)

    Farfan, E.; Jannik, T.

    2011-10-01

    This article describes results of the radiation environmental monitoring performed in the Chernobyl Exclusion Zone (ChEZ) during the period following the 1986 Chernobyl Nuclear Power Plant accident. This article presents a brief overview of five comprehensive reports generated under Contract No. DE-AC09-96SR18500 (Washington Savannah River Company LLC, Subcontract No. AC55559N, SOW No. ON8778) and summarizes characteristics of the ChEZ and its post-accident status and the history of development of the radiation monitoring research in the ChEZ is described. This article addresses characteristics of the radiation monitoring in the ChEZ, its major goals and objectives, and changes of these goals and objectives in the course of time, depending on the tasks associated with the phase of mitigation of the ChNPP accident consequences. The results of the radiation monitoring in the ChEZ during the last 25 years are also provided.

  18. Improving Physical Health in Patients With Chronic Mental Disorders: Twelve-Month Results From a Randomized Controlled Collaborative Care Trial.

    Science.gov (United States)

    Kilbourne, Amy M; Barbaresso, Michelle M; Lai, Zongshan; Nord, Kristina M; Bramlet, Margretta; Goodrich, David E; Post, Edward P; Almirall, Daniel; Bauer, Mark S

    2017-01-01

    Persons with chronic mental disorders are disproportionately burdened with physical health conditions. We determined whether Life Goals Collaborative Care compared to usual care improves physical health in patients with mental disorders within 12 months. This single-blind randomized controlled effectiveness study of a collaborative care model was conducted at a midwestern Veterans Affairs urban outpatient mental health clinic. Patients (N = 293 out of 474 eligible approached) with an ICD-9-CM diagnosis of schizophrenia, bipolar disorder, or major depressive disorder and at least 1 cardiovascular disease risk factor provided informed consent and were randomized (February 24, 2010, to April 29, 2015) to Life Goals (n = 146) or usual care (n = 147). A total of 287 completed baseline assessments, and 245 completed 12-month follow-up assessments. Life Goals included 5 weekly sessions that provided semistructured guidance on managing physical and mental health symptoms through healthy behavior changes, augmented by ongoing care coordination. The primary outcome was change in physical health-related quality of life score (Veterans RAND 12-item Short Form Health Survey [VR-12] physical health component score). Secondary outcomes included control of cardiovascular risk factors from baseline to 12 months (blood pressure, lipids, weight), mental health-related quality of life, and mental health symptoms. Among patients completing baseline and 12-month outcomes assessments (N = 245), the mean age was 55.3 years (SD = 10.8; range, 25-78 years), and 15.4% were female. Intent-to-treat analysis revealed that compared to those in usual care, patients randomized to Life Goals had slightly increased VR-12 physical health scores (coefficient = 3.21; P = .01). Patients with chronic mental disorders and cardiovascular disease risk who received Life Goals had improved physical health-related quality of life. ClinicalTrials.gov identifiers: NCT01487668 and NCT01244854.

  19. Twelve Month Weekly Monitoring of Stable Isotopes of Water Associated to the Flooding of the Meirama Open Pit (NW Spain)

    Science.gov (United States)

    Delgado, J.; Juncosa, R.; Vázquez, A.

    2009-04-01

    In December, 2007, after 30 years of extraction, the mine of Meirama stopped the production of brown lignite. Since April 2008, a controlled flooding process is taking place by which a large mining lake with nearly 150 cubic hectometers and a maximum depth of 180 meters will join the geography of Galicia in a few years. A weekly-based monitoring survey has been taking place in the lake since the beginning of the flooding process. Nearly 50 components and physico-chemical parameters of a series of sampling points located in the surface of the lake as well as in related tributaries, ground and rain waters are being recorded. Among the parameters analyzed, the stable isotopes of water (18-O and 2-H) are worth noting. The data collected so far help us to better understand the hydrological processes occurring in the first year of flooding and combined with different types of chemical constituents (conservative and non-conservative) put important constrains on the hydrochemical processes observed in the lake up to date.

  20. Monitoring the urban heat island of Bucharest (Romania) through a network of automatic meteorological sensors - first results

    Science.gov (United States)

    Cheval, Sorin; Lucaschi, Bogdan; Ioja, Cristian; Dumitrescu, Alexandru; Manea, Ancuta; Radulescu, Adrian; Dumitrache, Catalin; Tudorache, George; Vanau, Gabriel; Onose, Diana

    2015-04-01

    Extreme warm temperatures and heat waves represent one of the major climate hazards which impact the city of Bucharest (Romania), favoured by the climate background and by the urban characteristics. Previous studies based either on sparse ground sensors or satellite remote sensing indicate that the average differences between the monthly temperature of the built area and the neighbouring rural buffers of Bucharest can reach 3-4°C, but instantaneous values are certainly higher. Since the city shelters about 2 million residents, as well as the major administrative and economic facilities of the country, the hazard management should receive a vivid attention. The meteorological monitoring of the city is currently performed in a systematic manner by the National Meteorological Administration (NMA) through 3 ground-based stations following the standards of the World Meteorological Organization, and through radar and satellite remote sensing. In 2014, NMA set up 7 automatic sensors in specific urban conditions, while the University of Bucharest deployed 30 mobile sensors in a joint effort for enhancing the accuracy of the urban heat island monitoring. Both sensor devices are designed for continuous monitoring (24/7). This presentation focuses on the technical characteristics of the recently implemented network (1), and brings to the public the first results of the monitoring (2), including the implementation experience, the observed benefits and plans for development and applications. The data obtained are compared with the existing data sets from meteorological stations and satellite products, and they are currently integrated in a common database, providing valuable information about the Bucharest's urban heat island. The results have been obtained within the project UCLIMESA (Urban Heat Island Monitoring under Present and Future Climate), ongoing between 2013 and 2015 in the framework of the Programme for Research-Development-Innovation for Space Technology and

  1. Learning neuroendoscopy with an exoscope system (video telescopic operating monitor): Early clinical results

    Science.gov (United States)

    Parihar, Vijay; Yadav, Y. R.; Kher, Yatin; Ratre, Shailendra; Sethi, Ashish; Sharma, Dhananjaya

    2016-01-01

    Context: Steep learning curve is found initially in pure endoscopic procedures. Video telescopic operating monitor (VITOM) is an advance in rigid-lens telescope systems provides an alternative method for learning basics of neuroendoscopy with the help of the familiar principle of microneurosurgery. Aims: The aim was to evaluate the clinical utility of VITOM as a learning tool for neuroendoscopy. Materials and Methods: Video telescopic operating monitor was used 39 cranial and spinal procedures and its utility as a tool for minimally invasive neurosurgery and neuroendoscopy for initial learning curve was studied. Results: Video telescopic operating monitor was used in 25 cranial and 14 spinal procedures. Image quality is comparable to endoscope and microscope. Surgeons comfort improved with VITOM. Frequent repositioning of scope holder and lack of stereopsis is initial limiting factor was compensated for with repeated procedures. Conclusions: Video telescopic operating monitor is found useful to reduce initial learning curve of neuroendoscopy.

  2. CEM ultrasonic flow monitoring design, installation and certification results at the Salt River Project

    Energy Technology Data Exchange (ETDEWEB)

    Rihs, P.W. [Salt River Project, Saint Johns, AZ (United States). Coronado Generating Station

    1995-12-31

    This presentation will include Salt River Project`s design, installation, experiences and results using ultrasonic flow monitoring equipment for certification of continuous emissions monitoring systems. Flow Monitoring is the newest and has been the most controversial component of CEM systems. Experience in measuring flue gas volumetric flow prior to CEMs was very limited. There are currently three basic techniques used to measure gas flow: (1) thermal sensing using hotwire anemometer or thermal dispersion; (2) differential pressure (pitot tube and annubar); (3) acoustic using ultrasonic transducers. The Salt River Project (SRP) operates a variety of affected generating stations: coal, gas and oil. Ultrasonic flow monitoring technology was chosen for all affected generating stations which the author operates. SRP`s approach and reasoning for choosing ultrasonic systems will be discussed. A review of each generating station`s flow monitoring system will be presented. The presentation will include, but may not be limited to, the following: general facilities, description and schematics; physical installations, plan and section drawings; design considerations; results of flow monitors certification testing; and CEMs Project Manager`s conclusions.

  3. Current emission trends for nitrogen oxides, sulfur dioxide, and volatile organic compounds by month and state: Methodology and results

    Energy Technology Data Exchange (ETDEWEB)

    Kohout, E.J.; Miller, D.J.; Nieves, L.A.; Rothman, D.S.; Saricks, C.L.; Stodolsky, F.; Hanson, D.A.

    1990-08-01

    This report presents estimates of monthly sulfur dioxide (SO{sub 2}), nitrogen oxides (NO{sub x}), and nonmethane voltatile organic compound (VOC) emissions by sector, region, and state in the contiguous United States for the years 1975 through 1988. This work has been funded as part of the National Acid Precipitation Assessment Program`s Emissions and Controls Task Group by the US Department of Energy (DOE) Office of Fossil Energy (FE). The DOE project officer is Edward C. Trexler, DOE/FE Office of Planning and Environment.

  4. Current emission trends for nitrogen oxides, sulfur dioxide, and volatile organic compounds by month and state: Methodology and results

    Energy Technology Data Exchange (ETDEWEB)

    Kohout, E.J.; Miller, D.J.; Nieves, L.A.; Rothman, D.S.; Saricks, C.L.; Stodolsky, F.; Hanson, D.A.

    1990-08-01

    This report presents estimates of monthly sulfur dioxide (SO{sub 2}), nitrogen oxides (NO{sub x}), and nonmethane voltatile organic compound (VOC) emissions by sector, region, and state in the contiguous United States for the years 1975 through 1988. This work has been funded as part of the National Acid Precipitation Assessment Program's Emissions and Controls Task Group by the US Department of Energy (DOE) Office of Fossil Energy (FE). The DOE project officer is Edward C. Trexler, DOE/FE Office of Planning and Environment.

  5. Early results on wrist based heart rate monitoring using mechanical transducers.

    Science.gov (United States)

    Buxi, Dilpreet; Penders, Julien; van Hoof, Chris

    2010-01-01

    Heart rate monitoring has been a significant topic of interest in the areas of healthcare, sports and gaming. Compared to locations such as the neck, ear, or chest, the wrist is a convenient measurement point, as the measurement technology can be integrated into a wristwatch. However, key technical challenges exist, namely a small physiological SNR and large disturbances due to motion artifact. This paper reports early results on a packaging concept to monitor the heartrate during rest and motion using off-the-shelf piezoelectric PVDF film sensors. Evaluation has shown good results at rest and unsatisfactory results during motion. Results from this investigation will nonetheless be used as input for the development of a wrist-based heartrate monitor which could function during activities such as running, walking or typing on a keyboard.

  6. A community-based caries control program for pre-school children using topical fluorides: 18-month results.

    Science.gov (United States)

    Lo, E C; Chu, C H; Lin, H C

    2001-12-01

    Dental caries in Chinese pre-school children is common, and restorative treatment is not readily available. This prospective controlled clinical trial investigated the effectiveness of topical fluoride applications in arresting dentin caries. We divided 375 children (aged 3-5 yrs) with carious upper anterior teeth into five groups. Children in the first and second groups received annual applications of silver diamine fluoride solution (44,800 ppm F). NaF varnish (22,600 ppm F) was applied every three months onto the lesions of children in the third and fourth groups. For children in the first and third groups, soft carious tissues were removed prior to fluoride application. The fifth group was the control. We followed 341 children for 18 months. The mean numbers of new caries surfaces in the five groups were 0.4, 0.4, 0.8, 0.6, and 1.2, respectively (p = 0.001). The respective mean numbers of arrested carious tooth surfaces were 2.8, 3.0, 1.7, 1.5, and 1.0 (p < 0.001).

  7. Relationship of cravings with weight loss and hunger. Results from a 6 month worksite weight loss intervention.

    Science.gov (United States)

    Batra, Payal; Das, Sai Krupa; Salinardi, Taylor; Robinson, Lisa; Saltzman, Edward; Scott, Tammy; Pittas, Anastassios G; Roberts, Susan B

    2013-10-01

    We examined the association of food cravings with weight loss and eating behaviors in a lifestyle intervention for weight loss in worksites. This research was part of a randomized controlled trial of a 6-month weight loss intervention versus a wait-listed control in 4 Massachusetts worksites. The intervention emphasized reducing energy intake by adherence to portion-controlled menu suggestions, and assessments were obtained in 95 participants at baseline and 6 months including non-fasting body weight, food cravings (Craving Inventory and Food Craving Questionnaire for state and trait) and the eating behavior constructs restraint, disinhibition and hunger (Eating Inventory). There were statistically significant reductions in all craving variables in the intervention group compared to the controls. Within the intervention group, changes in craving-trait were significantly associated with weight loss after controlling for baseline weight, age, gender and worksite. However, in a multivariate model with craving-trait and eating behaviors (restraint, disinhibition and hunger), hunger was the only significant predictor of weight change. In contrast to some previous reports of increased food cravings with weight loss in lifestyle interventions, this study observed a broad reduction in cravings associated with weight loss. In addition, greater reductions in craving-trait were associated with greater weight change, but craving-trait was not a significant independent correlate of weight change when hunger was included in statistical models. Studies are needed to examine the effectiveness of hunger suppressing versus craving-suppressing strategies in lifestyle interventions for obesity.

  8. Safety profile of orlistat: results of a prescription-event monitoring study.

    Science.gov (United States)

    Acharya, N V; Wilton, L V; Shakir, S A W

    2006-11-01

    Orlistat, the first of a new class of drugs for the treatment of obesity, was launched in the UK in December 1998. The prescribing information recommends that treatment with orlistat should be discontinued after 12 weeks if the patient has not achieved a specified loss of weight. To monitor the safety of orlistat prescribed in the primary care setting in England using prescription-event monitoring (PEM). A postmarketing surveillance study using the observational cohort technique of PEM. Patients were identified from dispensed prescriptions issued by primary care physicians for orlistat between December 1998 and November 1999. The outcome data were event reports obtained by sending questionnaires (green forms) to the prescribing doctor at least 6 months after the first prescription for an individual patient. Incidence densities, expressed as number of first reports of an event/1000 patient-months of exposure, were calculated. Significant differences between incidence densities (IDs) for events reported in the 1st month (ID(1)) and months 2 and 3 (ID(2-3)) of exposure were regarded as potential signals. Reasons for stopping orlistat were analysed. Follow-up information was requested for selected events and used to assess the causal association with orlistat. Green forms containing clinically useful information on 16 021 patients (median age 45 years (interquartile range 35-54); 80.1% females) were received. The events reported most frequently during the 1st month of treatment were 'not effective' (639; 4.0% of cohort), diarrhoea (371; 2.3%) and weight loss (230; 1.4%). Twelve clinical adverse events were identified for which ID(1) was significantly greater than ID(2-3). These included non-specific events (e.g. intolerance, malaise/lassitude, unspecified side effects), weight loss and vaginitis/vulvitis. The remaining events were gastrointestinal in nature and included diarrhoea, pain abdomen, flatulence, nausea/vomiting, rectal discharge, faecal incontinence and

  9. Solvent hold tank sample results for MCU-14-913 and MCU-14-986/987: October 2014 monthly

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Taylor-Pashow, K. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-01-01

    SRNL received two sets of SHT samples (MCU-14-913, pulled 10/7/2014 and MCU-14-986/987, pulled on 10/27/2014) for analysis. The samples were analyzed for composition. Analysis of sample MCU-14- 913 indicated low concentrations of the suppressor (TiDG) and of the modifier (CS-7SB) in the solvent. The addition of suppressor and modifier to the solvent on October 26, 2014 restored the concentration of these components to nominal levels as confirmed with the analysis of sample MCU-14-986/987. The laboratory will continue to monitor the quality of the solvent in particular for any new impurity or degradation of the solvent components.

  10. Continuous electromagnetic radiation monitoring in the environment: analysis of the results in Greece.

    Science.gov (United States)

    Manassas, Athanasios; Boursianis, Achilles; Samaras, Theodoros; Sahalos, John N

    2012-09-01

    Non-ionising radiation-monitoring networks were initiated as a result of the public concerns about the potential health effects from telecommunication emissions. In the present study, the data acquired from such networks in Greece are used to assess the changes in the outdoor electromagnetic environment with respect to location and time. The study shows that there is a statistically significant difference between the urban (median electric field: 1.1 V m(-1)) and the rural (median electric field: 0.3 V m(-1)) installations of monitoring units and also shows that there is a median diurnal variation (daily maximum to minimum) of 20.2 and 33.8 % for the broadcasting and mobile telecommunication emissions, respectively. Moreover, there is a difference in the electric field between daytime and night, but not between morning and afternoon. The results are in line with previously published data from spot measurements, monitoring networks and personal exposimeter studies performed in several European countries.

  11. Acoustic emission and ultrasonic monitoring results from deposition hole DA3545G01 in the Prototype Repository between October 2009 and March 2010

    Energy Technology Data Exchange (ETDEWEB)

    Haycox, Jon; Andrews, Jennifer [ASC, Applied Seismology Consultants, Shrewsbury, Shropshire (United Kingdom)

    2010-09-15

    This report describes results from acoustic emission (AE) and ultrasonic monitoring around a canister deposition hole (DA3545G01) in the Prototype Repository Experiment at SKB's Hard Rock Laboratory (HRL), Sweden. The monitoring aims to examine changes in the rock mass caused by an experimental repository environment, in particular due to thermal stresses induced from canister heating and changes in pore pressures induced from tunnel sealing. Monitoring of this volume has previously been performed during excavation (Pettitt et al. 1999), and during stages of canister heating and tunnel pressurisation (Haycox and Pettitt 2005a, b, 2006a, b, 2009, Zolezzi et al. 2007, 2008, Duckworth et al. 2008, 2009, Haycox and Duckworth 2009). Further information on the previous monitoring periods can be found in Appendix 1. This report covers the period between 1st October 2009 and 31st March 2010 and is the tenth 6-monthly processing and interpretation of the results from the experiment.

  12. Acoustic emission and ultrasonic monitoring results from deposition hole DA3545G01 in the Prototype Repository between April 2009 and September 2009

    Energy Technology Data Exchange (ETDEWEB)

    Haycox, Jon; Pettitt, Will [ASC, Applied Seismology Consultants, Shrewsbury, Shropshire (United Kingdom)

    2009-12-15

    This report describes results from acoustic emission (AE) and ultrasonic monitoring around a canister deposition hole (DA3545G01) in the Prototype Repository Experiment at SKB's Hard Rock Laboratory (HRL), Sweden. The monitoring aims to examine changes in the rock mass caused by an experimental repository environment, in particular due to thermal stresses induced from canister heating and changes in pore pressures induced from tunnel sealing. Monitoring of this volume has previously been performed during excavation (Pettitt et al. 1999), and during stages of canister heating and tunnel pressurisation (Haycox and Pettitt 2005a, b, 2006a, b, Zolezzi et al. 2007, 2008, Duckworth et al. 2008, 2009, Haycox and Duckworth 2009). Further information on the previous monitoring undertaken can be found in Appendix 1. This report covers the period between 1st April 2009 and 30th September 2009 and is the ninth 6-monthly processing and interpretation of the results from the experiment.

  13. Acoustic emission and ultrasonic monitoring results from deposition hole DA3545G01 in the Prototype Repository between October 2008 and March 2009

    Energy Technology Data Exchange (ETDEWEB)

    Haycox, Jon; Duckworth, Damion [ASC, Applied Seismology Consultants, Shrewsbury, Shropshire (United Kingdom)

    2009-06-15

    This report describes results from acoustic emission (AE) and ultrasonic monitoring around a canister deposition hole (DA3545G01) in the Prototype Repository Experiment at SKB's Hard Rock Laboratory (HRL), Sweden. The monitoring aims to examine changes in the rock mass caused by an experimental repository environment, in particular due to thermal stresses induced from canister heating and changes in pore pressures induced from tunnel sealing. Monitoring of this volume has previously been performed during excavation (Pettitt et al. 1999), and during stages of canister heating and tunnel pressurisation (Haycox and Pettitt 2005a, b, 2006a, b, Zolezzi et al. 2007, 2008, Duckworth et al. 2008, 2009). Further information on the previous monitoring undertaken can be found in Appendix 1. This report covers the period between 1st October 2008 and 31st March 2009 and is the eighth 6-monthly processing and interpretation of the results from the experiment.

  14. Acoustic emission and ultrasonic monitoring results from deposition hole DA3545G01 in the Prototype Repository between October 2008 and March 2009

    Energy Technology Data Exchange (ETDEWEB)

    Haycox, Jon; Duckworth, Damion [ASC, Applied Seismology Consultants, Shrewsbury, Shropshire (United Kingdom)

    2009-06-15

    This report describes results from acoustic emission (AE) and ultrasonic monitoring around a canister deposition hole (DA3545G01) in the Prototype Repository Experiment at SKB's Hard Rock Laboratory (HRL), Sweden. The monitoring aims to examine changes in the rock mass caused by an experimental repository environment, in particular due to thermal stresses induced from canister heating and changes in pore pressures induced from tunnel sealing. Monitoring of this volume has previously been performed during excavation (Pettitt et al. 1999), and during stages of canister heating and tunnel pressurisation (Haycox and Pettitt 2005a, b, 2006a, b, Zolezzi et al. 2007, 2008, Duckworth et al. 2008, 2009). Further information on the previous monitoring undertaken can be found in Appendix 1. This report covers the period between 1st October 2008 and 31st March 2009 and is the eighth 6-monthly processing and interpretation of the results from the experiment.

  15. Acoustic emission and ultrasonic monitoring results from deposition hole DA3545G01 in the Prototype Repository between April 2009 and September 2009

    Energy Technology Data Exchange (ETDEWEB)

    Haycox, Jon; Pettitt, Will [ASC, Applied Seismology Consultants, Shrewsbury, Shropshire (United Kingdom)

    2009-12-15

    This report describes results from acoustic emission (AE) and ultrasonic monitoring around a canister deposition hole (DA3545G01) in the Prototype Repository Experiment at SKB's Hard Rock Laboratory (HRL), Sweden. The monitoring aims to examine changes in the rock mass caused by an experimental repository environment, in particular due to thermal stresses induced from canister heating and changes in pore pressures induced from tunnel sealing. Monitoring of this volume has previously been performed during excavation (Pettitt et al. 1999), and during stages of canister heating and tunnel pressurisation (Haycox and Pettitt 2005a, b, 2006a, b, Zolezzi et al. 2007, 2008, Duckworth et al. 2008, 2009, Haycox and Duckworth 2009). Further information on the previous monitoring undertaken can be found in Appendix 1. This report covers the period between 1st April 2009 and 30th September 2009 and is the ninth 6-monthly processing and interpretation of the results from the experiment.

  16. Acoustic emission and ultrasonic monitoring results from deposition hole DA3545G01 in the Prototype Repository between April 2010 and September 2010

    Energy Technology Data Exchange (ETDEWEB)

    Haycox, Jon (ASC Applied Seismology Consultants (United Kingdom))

    2011-05-15

    This report describes results from acoustic emission (AE) and ultrasonic monitoring around a canister deposition hole (DA3545G01) in the Prototype Repository Experiment at SKB's Hard Rock Laboratory (HRL), Sweden. The monitoring aims to examine changes in the rock mass caused by an experimental repository environment, in particular due to thermal stresses induced from canister heating and changes in pore pressures induced from tunnel sealing. Monitoring of this volume has previously been performed during excavation (Pettitt et al. 1999), and during stages of canister heating and tunnel pressurisation (Haycox and Pettitt 2005a, b, 2006a, b, Zolezzi et al. 2007, 2008, Duckworth et al. 2008, 2009, Haycox et al. 2009a, b, 2010). Appendix I contains further information about previous monitoring periods. This report covers the period between 1st April 2010 and 30th September 2010 and is the eleventh 6-monthly processing and interpretation of the results from the experiment

  17. Clinical evaluation of different adhesives used in the restoration of non-carious cervical lesions: 24-month results.

    Science.gov (United States)

    Tuncer, D; Yazici, A R; Özgünaltay, G; Dayangac, B

    2013-03-01

    The aim of this study was to compare after 24 months the clinical performance of cervical restorations placed with the use of an etch-and-rinse and an all-in-one adhesive. Twenty-four patients with at least one pair of non-carious cervical lesions participated in this study. One hundred and twenty-three cervical lesions were restored (62 etch-and-rinse adhesive, Solobond M; 61 all-in-one adhesive, Futurabond NR). A nanohybrid resin composite, Grandio, was used as the restorative material. Restorations were evaluated according to modified USPHS criteria by two independent examiners. The survival rates of the restorations were calculated by the Kaplan-Meier estimator and log-rank test. The restorations in each category were compared using the Pearson chi-square test, while the performance of restorations at the baseline and at each recall time was evaluated by McNemar's test (p adhesives (p > 0.05). None of the restorations had secondary caries, loss of anatomical form, or surface texture changes. Cervical restorations placed with an etch-and-rinse adhesive showed higher retention than an all-in-one adhesive. © 2013 Australian Dental Association.

  18. James Bay air quality study : report on the results of field monitoring in 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-02-08

    An air quality study in James Bay was conducted, in order to establish general levels of pollutants in outdoor air in the James Bay area of Victoria, British Columbia. The primary sources of air pollution in the area include light duty and heavy duty vehicle traffic, helicopters, floatplanes, and marine vessels such as cruise ships, passenger ferries, commercial fishing and whale watching boats, and recreation motorboats. Air quality monitoring represented the first phase of the project. The second phase involved a detailed pollutant dispersion model including all emission sources. This report described the use of sampling equipment and the measurement of nitric oxide, nitrogen dioxide, sulfur dioxide, fine particulate matter and contributing sources, and volatile organic compounds, specifically benzene, toluene, ethylbenzene/xylene and naphthalene. Supporting data, including traffic counts, wind speed and direction, precipitation, and cruise ship schedules were collected to assist in the interpretation of the field monitoring results. For each of these pollutants, the report provided responses to several questions, such as defining each pollutant; describing the sources of each pollutant in the James Bay neighbourhood; presenting the results of the field monitoring; discussing the limitations of the monitoring equipment and sampling design; interpreting the results; comparing monitored levels to those measured at other times or locations; and comparing monitored levels to air quality standards or guidelines. Conclusions about each pollutant were presented. It was concluded that phase 2 pollutant dispersion modelling should include estimates of 1-hour, 24-hour, and seasonal average pollutant levels at varying elevations above ground level, with a focus on residential apartment buildings in the study area. 5 tabs., 52 figs., 7 appendices.

  19. Blood lead levels in the adult Victorian population: results from the Victorian Health Monitor.

    Science.gov (United States)

    Kelsall, Liza M; de Gooyer, Tanyth E; Carey, Marion; Vaughan, Loretta; Ansari, Zahid

    2013-06-01

    To estimate blood lead levels (BLLs) in the adult Victorian population and compare the distribution of BLLs with the current national reference level to better inform public health prevention and management of lead toxicity. Population-based cross-sectional health measurement survey of 50 randomly selected Census Collection Districts (CDs) throughout Victoria. The Victorian Health Monitor (VHM) was conducted over 12 months from May 2009 to April 2010. One eligible person (aged 18-75 years) from each household selected within each CD was randomly selected to participate. Persons with an intellectual disability and pregnant women were excluded from the sampling frame. BLLs were obtained from 3,622 of the 3,653 (99%) VHM participants. The geometric mean and median BLLs from the adult sample were 0.070 μmol/L (95%CI, 0.068-0.073) and 0.05 μmol/L (range: 0.05 to 1.22 μmol/L), respectively. Elevated BLLs (≥0.483 μmol/L or ≥10 μg/dL) were identified in 19 participants (0.7%; 95%CI, 0.3-1.6). Additionally, 86 participants (1.8%; 95%CI, 1.3-2.4) were identified with BLLs between 0.242 and <0.483 μmol/L (5 to <10 μg/dL). The geometric mean BLL was significantly higher for males, compared with females (0.077 μmol/L vs 0.064 μmol/L; p<0.001). BLLs increased significantly with age for both sexes. The first population estimates of BLLs in Victorian adults indicate the average adult BLL to be well below the current national reference level. However, some groups of the population have BLLs at which adverse effects may occur. Implications : The results provide baseline estimates for future population health surveillance and comparison with studies of at-risk groups. © 2013 The Authors. ANZJPH © 2013 Public Health Association of Australia.

  20. Calibration of qualitative HBsAg assay results for quantitative HBsAg monitoring.

    Science.gov (United States)

    Gunning, Hans; Adachi, Dena; Tang, Julian W

    2014-10-01

    Evidence is accumulating that quantitative hepatitis B surface antigen monitoring may be useful in managing patients with chronic HBV infection on certain treatment regimens. Based on these results with the Abbott Architect qualitative and quantitative HBsAg assays, it seems feasible to convert qualitative to quantitative HBsAg values for this purpose. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Results of a monitoring pilot with a permanent buried multicomponent seismic array at Ketzin

    NARCIS (Netherlands)

    Arts, R.J.; Meekes, J.A.C.; Brouwer, J.H.; Werf, M. van der; Noorlandt, R.P.; Paap, B.; Visser, W.; Vandeweijer, V.; Lüth, S.; Giese, R.; Maas, J.

    2011-01-01

    To monitor the migration of the injected CO2 in the Ketzin project (Germany) a permanently buried multi-component seismic array has been installed in August 2009. Since then the array has been continuously recording passive seismic data. Additionally an active seismic survey resulting in a 230 m lon

  2. Monitoring of radiation in atmosphere, water and a food chain. Results in the Netherlands in 1991

    NARCIS (Netherlands)

    Kwakman PJM; Aldenkamp FJ; de Vries LJ; Drost RMS; Tijsmans MH; Koolwijk AC; Ockhuizen A

    1993-01-01

    This 1991 annual report presents the results of radioactivity measurements in biosphere samples taken in the Netherlands. The National Measurement Programme (NMP), considered essential for an adequate assessment of radioactivity in the biospere, includes the monitoring of air, deposition and surfac

  3. Results from multipoint alignment monitoring using the new generation of amorphous silicon position detectors

    Energy Technology Data Exchange (ETDEWEB)

    Alberdi, J.; Arce, P.; Barcala, J.M.; Calvo, E. [CIEMAT, 28040 Madrid (Spain); Ferrando, A. [CIEMAT, 28040 Madrid (Spain)], E-mail: antonio.ferrando@ciemat.es; Josa, M.I.; Molinero, A.; Navarrete, J.; Oller, J.C.; Yuste, C. [CIEMAT, 28040 Madrid (Spain); Calderon, A.; Gomez, G.; Gonzalez-Sanchez, F.J.; Martinez-Rivero, C.; Matorras, F.; Rodrigo, T.; Ruiz-Arbol, P.; Sobron, M.; Vila, I.; Virto, A.L. [Instituto de Fisica de Cantabria (IFCA), CSIC-University of Cantabria Santander (Spain)] (and others)

    2008-08-11

    We present the measured performance of a new generation of large sensitive area (28x28 mm{sup 2}) semitransparent amorphous silicon position detector sensors. More than 100 units have been characterized. They show a very high performance. To illustrate a multipoint application, we present results from the monitoring of five sensors placed in a 5.5-m-long light path.

  4. The CMS RPC gas gain monitoring system: an overview and preliminary results

    CERN Document Server

    Benussi, L; Colafranceschi, S; Colonna, D; Daniello, L; Fabbri, F L; Giardoni, M; Ortenzi, B; Paolozzi, A; Passamonti, L; Pierluigi, D; Ponzio, B; Pucci, C; Russo, A; Roselli, G; Colaleo, A; Loddo, F; Maggi, M; Ranieri, A; Abbrescia, M; Iaselli, G; Marangelli, B; Natali, S; Nuzzo, S; Pugliese, G; Romano, F; Trentadue, R; Tupputi, S; Guida, R; Polese, G; Cavallo, N; Cimmino, A; Lomidze, D; Noli, P; Paolucci, D; Piccolo, P; Sciacca, C; Baesso, P; Necchi, M; Pagano, D; Ratti, S P; Vitulo, P; Viviani, C

    2009-01-01

    The status of the CMS RPC Gas Gain Monitoring (GGM) system developed at the Frascati Laboratory of INFN (Istituto Nazionale di Fisica Nucleare) is reported on. The GGM system is a cosmic ray telescope based on small RPC detectors operated with the same gas mixture used by the CMS RPC system. The GGM gain and efficiency are continuously monitored on-line, thus providing a fast and accurate determination of any shift in working point conditions. The construction details and the first result of GGM commissioning are described.

  5. Results of a monitoring pilot with a permanent buried multicomponent seismic array at Ketzin

    OpenAIRE

    2011-01-01

    To monitor the migration of the injected CO2 in the Ketzin project (Germany) a permanently buried multi-component seismic array has been installed in August 2009. Since then the array has been continuously recording passive seismic data. Additionally an active seismic survey resulting in a 230 m long 2D seismic line roughly passing over the monitoring well Ktzi 202/2007 has been acquired in November 2009. This relatively small set-up is meant as a pre-screening study to demonstrate the added ...

  6. Integrating monitor alarms with laboratory test results to enhance patient deterioration prediction.

    Science.gov (United States)

    Bai, Yong; Do, Duc H; Harris, Patricia Rae Eileen; Schindler, Daniel; Boyle, Noel G; Drew, Barbara J; Hu, Xiao

    2015-02-01

    Patient monitors in modern hospitals have become ubiquitous but they generate an excessive number of false alarms causing alarm fatigue. Our previous work showed that combinations of frequently co-occurring monitor alarms, called SuperAlarm patterns, were capable of predicting in-hospital code blue events at a lower alarm frequency. In the present study, we extend the conceptual domain of a SuperAlarm to incorporate laboratory test results along with monitor alarms so as to build an integrated data set to mine SuperAlarm patterns. We propose two approaches to integrate monitor alarms with laboratory test results and use a maximal frequent itemsets mining algorithm to find SuperAlarm patterns. Under an acceptable false positive rate FPRmax, optimal parameters including the minimum support threshold and the length of time window for the algorithm to find the combinations of monitor alarms and laboratory test results are determined based on a 10-fold cross-validation set. SuperAlarm candidates are generated under these optimal parameters. The final SuperAlarm patterns are obtained by further removing the candidates with false positive rate>FPRmax. The performance of SuperAlarm patterns are assessed using an independent test data set. First, we calculate the sensitivity with respect to prediction window and the sensitivity with respect to lead time. Second, we calculate the false SuperAlarm ratio (ratio of the hourly number of SuperAlarm triggers for control patients to that of the monitor alarms, or that of regular monitor alarms plus laboratory test results if the SuperAlarm patterns contain laboratory test results) and the work-up to detection ratio, WDR (ratio of the number of patients triggering any SuperAlarm patterns to that of code blue patients triggering any SuperAlarm patterns). The experiment results demonstrate that when varying FPRmax between 0.02 and 0.15, the SuperAlarm patterns composed of monitor alarms along with the last two laboratory test results

  7. Preliminary Results of Subsurface Exploration and Monitoring at the Johnson Creek Landslide, Lincoln County, Oregon

    Science.gov (United States)

    Schulz, William H.; Ellis, William L.

    2007-01-01

    The Johnson Creek landslide is a translational, primarily bedrock landslide located along the Oregon coast about 5 km north of Newport. The landslide has damaged U.S. Highway 101 many times since construction of the highway and at least two geological and geotechnical investigations of the landslide have been performed by Oregon State agencies. In cooperation with the Oregon Department of Geology and Mineral Industries and the Oregon Department of Transportation, the U.S. Geological Survey upgraded landslide monitoring systems and installed additional monitoring devices at the landslide beginning in 2004. Monitoring devices at the landslide measured landslide displacement, rainfall, air temperature, shallow soil-water content, and ground-water temperature and pressure. The devices were connected to automatic dataloggers and read at one-hour and, more recently, 15-minute intervals. Monitoring results were periodically downloaded from the dataloggers using cellular telemetry. The purposes of this report are to describe and present preliminary monitoring data from November 19, 2004, to March 31, 2007.

  8. ANITA Air Monitoring on the International Space Station: Results Compared to Other Measurements

    Science.gov (United States)

    Honne, A.; Schumann-Olsen, H.; Kaspersen, K.; Limero, T.; Macatangay, A.; Mosebach, H.; Kampf, D.; Mudgett, P. D.; James, J. T.; Tan, G.; hide

    2009-01-01

    ANITA (Analysing Interferometer for Ambient Air) is a flight experiment precursor for a permanent continuous air quality monitoring system on the ISS (International Space Station). For the safety of the crew, ANITA can detect and quantify quasi-online and simultaneously 33 gas compounds in the air with ppm or sub-ppm detection limits. The autonomous measurement system is based on FTIR (Fourier Transform Infra-Red spectroscopy). The system represents a versatile air quality monitor, allowing for the first time the detection and monitoring of trace gas dynamics in a spacecraft atmosphere. ANITA operated on the ISS from September 2007 to August 2008. This paper summarizes the results of ANITA s air analyses with emphasis on comparisons to other measurements. The main basis of comparison is NASA s set of grab samples taken onboard the ISS and analysed on ground applying various GC-based (Gas Chromatography) systems.

  9. Clinical evaluation of the ability of a proprietary scoliosis traction chair to de-rotate the spine: 6-month results of Cobb angle and rotational measurements

    Directory of Open Access Journals (Sweden)

    Clayton J. Stitzel

    2014-10-01

    Full Text Available The aim of this study was to investigate the immediate and 6-month effects of a scoliosis traction chair on scoliosis rotation and Cobb angle. The scoliosis traction chair has been used clinically for 10 years and has been part of previous studies, but has not been the focus of any previous study. Our goal was to test the scoliosis traction chair’s ability to de-rotate the spine to create scoliosis correction. Fifteen patient files were retrospectively selected for study. Patients were radiographically studied in a proprietary traction chair to evaluate impact on Cobb angle and apical vertebral rotation. Six-month follow-up results were recorded. Six-month results showed an average overall Cobb angle increase of about 7°. Patients with in-chair apical de-rotation showed 9° of Cobb angle improvement, while those with increased in-chair apical rotation showed an average 16° progression. Scoliotic curves whose apical rotation worsened on stress radiography showed deterioration of the curve at 6 months. Those with improved apical rotation showed Cobb angle corrections at 6 months. Since progression of scoliotic curvatures was observed in our cohort of patients after 6 months of home and clinical use, it is imperative that further studies attempt to qualify which patients and scoliosis curve patterns are best suited for the scoliosis traction chair.

  10. Area Monitoring Dosimeter Program for the Pacific Northwest National Laboratory: Results for CY 1998

    Energy Technology Data Exchange (ETDEWEB)

    SR Bivins; GA Stoetzel

    1999-06-17

    In January 1993, Pacific Northwest National Laboratory (PNNL) established an area monitoring dosimeter program in accordance with Article 514 of the Department of Energy (DOE) Radiological Control Manual (RCM). The purpose of the program was to minimize the number of areas requiring issuance of personnel dosimeters and to demonstrate that doses outside Radiological Buffer Areas are negligible. In accordance with 10 CFR Part 835.402 (a)(1)-(4) and Article 511.1 of the RCM, personnel dosimetry shall be provided to (1) radiological workers who are likely to receive at least 100 mrem annually and (2) declared pregnant workers, minors, and members of the public who are likely to receive at least 50 mrem annually. Program results for calendar years 1993-1997 confirmed that personnel dosimetry was not needed for individuals located in areas monitored by the program. A total of 97 area thermoluminescent dosimeters (TLDs) were placed in PNNL facilities during calendar year 1998. The TLDs were exchanged and analyzed quarterly. All routine area monitoring TLD results were less than 50 mrem annually after correcting for worker occupancy. The results support the conclusion that personnel dosimeters are not necessary for staff, declared pregnant workers, minors, or members of the public in these monitored areas.

  11. Area Monitoring Dosimeter Program for the Pacific Northwest National Laboratory: Results for CY 1999

    Energy Technology Data Exchange (ETDEWEB)

    Bivins, Steven R.; Stoetzel, Gregory A.

    2000-09-19

    In January 1993, PNNL established an area monitoring dosimeter program in accordance with Article 514 of the DOE Radiological Control Manual. This program was to minimize the number of areas requiring issuance of personnel dosimeters and to demonstrate that doses outside Radiological Buffer Areas are negligible. In accordance with 10 CFR Part 835.402 (a)(1)-(4) and Article 511.1 of the DOE Standard Radiological Control, personnel dosimetry shall be provided to 1) radiological workers who are likely to receive at least 100 mrem annually and 2) declared pregnant workers, minors, and members of the public who are likely to receive at least 50 mrem annually. Program results for calendar years 1993-1998 confirmed that personnel dosimetry was not needed for individuals located in areas monitored by the program. A total of 123 area thermoluminescent dosimeters (TLDs) were placed in PNNL facilities during calendar year 1999. The TLDs were exchanged and analyzed quarterly. All routine area monitoring TLD results were less than 50 mrem annually after correcting for worker occupancy. The results support the conclusion that personnel dosimeters are not necessary for staff, declared pregnant workers, minors, or members of the public in these monitored areas.

  12. Area monitoring dosimeter program for the Pacific Northwest National Laboratory: Results for CY 1996

    Energy Technology Data Exchange (ETDEWEB)

    Bivins, S R; Stoetzel, G A

    1997-06-01

    In January 1993, Pacific Northwest National Laboratory (PNNL) established an area monitoring dosimeter program in accordance with Article 514 of the Department of Energy (DOE) Radiological Control Manual (RCM). The purpose of the program was to minimize the number of areas requiring issuance of personnel dosimeters and to demonstrate that doses outside Radiological buffer Areas are negligible. In accordance with 10 CFR Part 835.402 (a) (1)-(3) and Article 511.1 of the RCM, personnel dosimetry shall be provided to (1) radiological workers who are likely to receive at least 100 mrem annually and (2) declared pregnant workers, minors, and members of the public who are likely to receive at least 50 mrem annually. Program results for calendar years 1993, 1994, and 1995 confirmed that personnel dosimetry was not needed for individuals located in areas monitored by the program. A total of 108 area TLDs were placed in PNNL facilities during CY 1996. The TLDs were exchanged and analyzed quarterly. All routine area monitoring TLD results were less than 50 mrem annually after correcting for worker occupancy. The results support the conclusion that personnel dosimeters are not necessary for staff, declared pregnant workers, minors, or members of the public in these monitored areas.

  13. Area monitoring dosimeter program for the Pacific Northwest National Laboratory: Results for CY 1997

    Energy Technology Data Exchange (ETDEWEB)

    Bivins, S.R.; Stoetzel, G.A.

    1998-07-01

    In January 1993, Pacific Northwest National Laboratory (PNNL) established an area monitoring dosimeter program in accordance with Article 514 of the US Department of Energy (DOE) Radiological Control Manual (RCM). The purpose of the program was to minimize the number of areas requiring issuance of personnel dosimeters and to demonstrate that doses outside Radiological Buffer Areas are negligible. In accordance with 10 CFR Part 835.402 (a) (1)--(3) and Article 511.1 of the RCM, personnel dosimetry shall be provided to (1) radiological workers who are likely to receive at least 100 mrem annually, and (2) declared pregnant workers, minors, and members of the public who are likely to receive at least 50 mrem annually. Program results for calendar years (CY) 1993--1996 confirmed that personnel dosimetry was not needed for individuals located in areas monitored by the program. A total of 93 area thermoluminescent dosimeters (TLDs) were placed in PNNL facilities during CY 1997. The TLDs were exchanged and analyzed quarterly. All routine area monitoring TLD results were less than 50 mrem annually after correcting for worker occupancy. The results support the conclusions that personnel dosimeters are not necessary for staff, declared pregnant workers, minors, or members of the public in these monitored areas.

  14. On the rapid and efficient divulgation of monitoring results in landslide emergency scenarios

    Science.gov (United States)

    Giordan, Daniele; Allasia, Paolo; Manconi, Andrea; Bertolo, Davide

    2014-05-01

    In last decades, the availability of several technological systems to monitor different physical parameters that can be used to control a landslide evolution recorded an exponential growth. In particular, surficial and deep-seated displacements of an instable area, as well as meteorological or hydrological parameters can be nowadays acquired with high spatial and temporal resolutions. As a consequence, the application of complex monitoring systems produces large amounts of data. While this can be considered an important progress in the field of landslide monitoring applications, the availability of large volumes of high resolution and multiparametric information implies important challenges. In this context, two main criticalities are: i) the integrated management of dataset produced by different monitoring systems and ii) the correct divulgation of monitoring results. In this work, we present the results of a real case-study relevant to a complex emergency scenario, i.e. the Mont de La Saxe landslide, a large rockslide (with an estimated volume or more than 8 million of cubic meters) that threatens La Palud and Entrèves hamlets in the Courmayeur municipality (Aosta Valley, Italy). We developed a web-based system based on the ADVICE algorithm (Allasia et al., 2013) in order to manage several data sources. The system collects, analyzes and publishes the results obtained by monitoring instrumentations in near-real-time at each new measurement cycle. Moreover, by collecting all the data in an unique web-based platform reduces the problems of compatibility amongst different monitoring systems, which usually rely on customized software for the data processing, delaying the comparative analysis comparison amongst different data sources. This is indeed a crucial task for decision makers, in particular during the emergency phases. In addition, by using the developed web-based platform we aimed at coping with another important task, often not considered and

  15. The evaluation of Tracp5b as a marker for monitoring treatment results of bone metastasis in breast cancer patients

    Institute of Scientific and Technical Information of China (English)

    Xiaoyun Huang; Yan Si; Jia Zhao; Qiang Ding

    2008-01-01

    Objective:To evaluate the sensitivity of serum tartrate-resistant acid phosphatase 5b(Tracp5b) activity in monitoring bisphosphonate treatment results of bone metastasis in breast cancer(BC) patients. Methods:The serum activities of Tracp5b, CEA, CA153 were measured in 58 BC patients, including 26 without bone metastasis, 32 with bone metastasis. The serum activities of Tracp5b, CEA, CA153 were also measured in 19 patients with bone metastasis after 3 months of bisphosphonate treatment. Eighteen healthy women with age from 34 to 70 served as control. Results:Serum Tracp5b was significantly elevated in patients with bone metastasis compared with that in all any other groups(P< 0.05). The sensitivity of TracpSb was 78.13% and the specificity was 86.36%. The sensitivity of CA153 was 37.50% and the specificity was 77.27%. The sensitivity of CEA was 21.88% and the specificity was 84.09%. The serum activity of Tracp5b decreased significantly(P < 0.05) after 3 months of bisphosphonate treatment, while the levels of CA153 and CEA were unchanged. Conclusion:Serum TracpSb activity is a useful diagnostic marker for bone metastasis in BC patients and can be used to evaluate the treatment results of bisphosphonate.

  16. Geoelectrical monitoring of landslides: results from the sites of Laakirchen (Austria) and Rosano (Italy)

    Science.gov (United States)

    Guardiani, Carlotta; Amabile, Anna Sara; Jochum, Birgit; Ottowitz, David; Supper, Robert

    2017-04-01

    One of the main precursors for landslide activation/reactivation is intense and prolonged precipitation, with consequent pore water pressure rise due to infiltration of rainfall that seeps into the ground. Monitoring hydrological parameters such as precipitation, water content and pore pressure, in combination with displacement analysis for early warning purposes, is necessary to understand the triggering processes. Since the reduction over time of electrical resistivity corresponds to an increase of water content, electrical resistivity monitoring can help to interpret the modifications of slope saturation conditions after heavy rainfalls. In this study, we present the results of the ERT monitoring data from two landslide areas, Laakirchen (47.961692N, 13.809897E) and Rosano (44.662453N, 9.104703E). During March 2010, a shallow rotational landslide was triggered by snow melting and intense rainfall in Laakirchen, in the vicinity of a newly constructed house. Laakirchen landslide was monitored by geophysical/geotechnical measurements from September 2011 to June 2013. In December 2004, Rosano landslide reactivation affected rural buildings: slope deformations caused mainly damages to properties, infrastructures and lifelines. Rosano landslide has been defined as a composite landslide, with a general dynamic behavior that can be regarded as a slow earthflow. The installation of the monitoring system took place in July 2012 and the data acquisition lasted until April 2015. These sites are part of the geoelectrical monitoring network set up by the Geological Survey of Austria for testing the self-developed GEOMON4D geoelectrical system, in combination with complementary geotechnical monitoring sensors (rain gauge, automatic inclinometer, water pressure and water content sensors) to support the interpretation of the electrical response of the near surface (R. Supper et al., 2014). The measurements were funded by the TEMPEL project (Austrian Science Fund, TRP 175-N21

  17. Monitoring of radiation in the environment in the Netherlands. Results in 2001

    CERN Document Server

    Knetsch, G J

    2002-01-01

    This report presents the results of radioactivity measurements in the Dutch environment in 2001. The measurements were carried out by RIVM, RIZA, RIKZ and Inspectorate for Health Protection and Veterinary Public Health. Radioactivity measurements were carried out on airborne particles, deposition, surface water, seawater, drinking water and food (honey, powdered milk, game, poultry, blueberry and chanterelle). Results for ambient dose equivalent rates were obtained from the National Radioactivity Monitoring Network. The levels of radioactivity in the Dutch environment were not elevated in 2001

  18. Monitoring of radiation in the environment in the Netherlands. Results in 2001

    Energy Technology Data Exchange (ETDEWEB)

    Knetsch, G.J. (ed.)

    2002-07-01

    This report presents the results of radioactivity measurements in the Dutch environment in 2001. The measurements were carried out by RIVM, RIZA, RIKZ and Inspectorate for Health Protection and Veterinary Public Health. Radioactivity measurements were carried out on airborne particles, deposition, surface water, seawater, drinking water and food (honey, powdered milk, game, poultry, blueberry and chanterelle). Results for ambient dose equivalent rates were obtained from the National Radioactivity Monitoring Network. The levels of radioactivity in the Dutch environment were not elevated in 2001.

  19. Results from the Big Spring basin water quality monitoring and demonstration projects, Iowa, USA

    Science.gov (United States)

    Rowden, R.D.; Liu, H.; Libra, R.D.

    2001-01-01

    Agricultural practices, hydrology, and water quality of the 267-km2 Big Spring groundwater drainage basin in Clayton County, Iowa, have been monitored since 1981. Land use is agricultural; nitrate-nitrogen (-N) and herbicides are the resulting contaminants in groundwater and surface water. Ordovician Galena Group carbonate rocks comprise the main aquifer in the basin. Recharge to this karstic aquifer is by infiltration, augmented by sinkhole-captured runoff. Groundwater is discharged at Big Spring, where quantity and quality of the discharge are monitored. Monitoring has shown a threefold increase in groundwater nitrate-N concentrations from the 1960s to the early 1980s. The nitrate-N discharged from the basin typically is equivalent to over one-third of the nitrogen fertilizer applied, with larger losses during wetter years. Atrazine is present in groundwater all year; however, contaminant concentrations in the groundwater respond directly to recharge events, and unique chemical signatures of infiltration versus runoff recharge are detectable in the discharge from Big Spring. Education and demonstration efforts have reduced nitrogen fertilizer application rates by one-third since 1981. Relating declines in nitrate and pesticide concentrations to inputs of nitrogen fertilizer and pesticides at Big Spring is problematic. Annual recharge has varied five-fold during monitoring, overshadowing any water-quality improvements resulting from incrementally decreased inputs. ?? Springer-Verlag 2001.

  20. Students' Progression in Monitoring Anomalous Results Obtained in Inquiry-Based Laboratory Tasks

    Science.gov (United States)

    Crujeiras-Pérez, Beatriz; Jiménez-Aleixandre, Maria Pilar

    2017-07-01

    This paper examines students' engagement in monitoring anomalous results across a 2-year longitudinal study with 9th and 10th graders (14-15 and 15-16 years of age). The context is a set of five inquiry-based laboratory tasks, requiring students to plan and carry out investigations. The study seeks to examine students' interpretation of data, in particular anomalous results generated by them during the process of solving the tasks, and their ability to monitor them. Data collected include video and audio recordings as well as students' written products. For the analysis, two rubrics were developed drawing on Chinn and Brewer (Cognition and Instruction, 19, 323-393, 2001) and Hmelo-Silver et al. (Science Education, 86, 219-243, 2002). The findings point to a pattern of progress in students' responses across the 2 years: (a) responses revealing a low capacity of monitoring due to not recognizing the data as anomalous or recognizing it as anomalous but being unable to explain their causes are more frequent in the first tasks and (b) responses revealing an improved capacity of monitoring are more frequent in the last tasks. The factors influencing students' regulation of their performances, as the requirement of planning, and specific scaffolding based on activity theory are discussed.

  1. Temporal disaggregation of satellite-derived monthly precipitation estimates and the resulting propagation of error in partitioning of water at the land surface

    Directory of Open Access Journals (Sweden)

    S.A. Margulis

    2001-01-01

    Full Text Available Global estimates of precipitation can now be made using data from a combination of geosynchronous and low earth-orbit satellites. However, revisit patterns of polar-orbiting satellites and the need to sample mixed-clouds scenes from geosynchronous satellites leads to the coarsening of the temporal resolution to the monthly scale. There are prohibitive limitations to the applicability of monthly-scale aggregated precipitation estimates in many hydrological applications. The nonlinear and threshold dependencies of surface hydrological processes on precipitation may cause the hydrological response of the surface to vary considerably based on the intermittent temporal structure of the forcing. Therefore, to make the monthly satellite data useful for hydrological applications (i.e. water balance studies, rainfall-runoff modelling, etc., it is necessary to disaggregate the monthly precipitation estimates into shorter time intervals so that they may be used in surface hydrology models. In this study, two simple statistical disaggregation schemes are developed for use with monthly precipitation estimates provided by satellites. The two techniques are shown to perform relatively well in introducing a reasonable temporal structure into the disaggregated time series. An ensemble of disaggregated realisations was routed through two land surface models of varying complexity so that the error propagation that takes place over the course of the month could be characterised. Results suggest that one of the proposed disaggregation schemes can be used in hydrological applications without introducing significant error. Keywords: precipitation, temporal disaggregation, hydrological modelling, error propagation

  2. Maternal Diet and Weight at 3 Months Postpartum Following a Pregnancy Intervention with a Low Glycaemic Index Diet: Results from the ROLO Randomised Control Trial

    Directory of Open Access Journals (Sweden)

    Mary K. Horan

    2014-07-01

    Full Text Available Pregnancy increases the risk of being overweight at a later time period, particularly when there is excessive gestational weight gain. There remains a paucity of data into the effect of low glycaemic index (GI pregnancy interventions postpartum. Aim: To examine the impact of a low glycaemic index diet during pregnancy on maternal diet 3 months postpartum. Methodology: This analysis examined the diet, weight and lifestyle of 460 participants of the ROLO study 3 months postpartum. Questionnaires on weight, physical activity, breastfeeding, supplement use, food label reading and dietary habits were completed. Results: The intervention group had significantly greater weight loss from pre-pregnancy to 3 months postpartum than the control group (1.3 vs. 0.1 kg, p = 0.022. The intervention group reported greater numbers following a low glycaemic index diet (p < 0.001 and reading food labels (p = 0.032 and had a lower glycaemic load (GL (128 vs. 145, p = 0.014 but not GI (55 vs. 55, p = 0.809 than controls. Conclusions: Low GI dietary interventions in pregnancy result in improved health-behaviours and continued reported compliance at 3 months postpartum possibly through lower dietary GL as a result of portion control. Greater levels of weight loss from pre-pregnancy to 3 months postpartum in the intervention group may have important positive implications for overweight and obesity.

  3. The Satellite based Monitoring Initiative for Regional Air quality (SAMIRA): Project summary and first results

    Science.gov (United States)

    Schneider, Philipp; Stebel, Kerstin; Ajtai, Nicolae; Diamandi, Andrei; Horalek, Jan; Nemuc, Anca; Stachlewska, Iwona; Zehner, Claus

    2017-04-01

    We present a summary and some first results of a new ESA-funded project entitled Satellite based Monitoring Initiative for Regional Air quality (SAMIRA), which aims at improving regional and local air quality monitoring through synergetic use of data from present and upcoming satellite instruments, traditionally used in situ air quality monitoring networks and output from chemical transport models. Through collaborative efforts in four countries, namely Romania, Poland, the Czech Republic and Norway, all with existing air quality problems, SAMIRA intends to support the involved institutions and associated users in their national monitoring and reporting mandates as well as to generate novel research in this area. The primary goal of SAMIRA is to demonstrate the usefulness of existing and future satellite products of air quality for improving monitoring and mapping of air pollution at the regional scale. A total of six core activities are being carried out in order to achieve this goal: Firstly, the project is developing and optimizing algorithms for the retrieval of hourly aerosol optical depth (AOD) maps from the Spinning Enhanced Visible and InfraRed Imager (SEVIRI) onboard of Meteosat Second Generation. As a second activity, SAMIRA aims to derive particulate matter (PM2.5) estimates from AOD data by developing robust algorithms for AOD-to-PM conversion with the support from model- and Lidar data. In a third activity, we evaluate the added value of satellite products of atmospheric composition for operational European-scale air quality mapping using geostatistics and auxiliary datasets. The additional benefit of satellite-based monitoring over existing monitoring techniques (in situ, models) is tested by combining these datasets using geostatistical methods and demonstrated for nitrogen dioxide (NO2), sulphur dioxide (SO2), and aerosol optical depth/particulate matter. As a fourth activity, the project is developing novel algorithms for downscaling coarse

  4. Haemodynamic Monitoring in the Intensive Care Unit: Results from a Web-Based Swiss Survey

    Directory of Open Access Journals (Sweden)

    Nils Siegenthaler

    2014-01-01

    Full Text Available Background. The aim of this survey was to describe, in a situation of growing availability of monitoring devices and parameters, the practices in haemodynamic monitoring at the bedside. Methods. We conducted a Web-based survey in Swiss adult ICUs (2009-2010. The questionnaire explored the kind of monitoring used and how the fluid management was addressed. Results. Our survey included 71% of Swiss ICUs. Echocardiography (95%, pulmonary artery catheter (PAC: 85%, and transpulmonary thermodilution (TPTD (82% were the most commonly used. TPTD and PAC were frequently both available, although TPTD was the preferred technique. Echocardiography was widely available (95% but seems to be rarely performed by intensivists themselves. Guidelines for the management of fluid infusion were available in 45% of ICUs. For the prediction of fluid responsiveness, intensivists rely preferentially on dynamic indices or echocardiographic parameters, but static parameters, such as central venous pressure or pulmonary artery occlusion pressure, were still used. Conclusions. In most Swiss ICUs, multiple haemodynamic monitoring devices are available, although TPTD is most commonly used. Despite the usefulness of echocardiography and its large availability, it is not widely performed by Swiss intensivists themselves. Regarding fluid management, several parameters are used without a clear consensus for the optimal method.

  5. Cadmium, lead, mercury and arsenic in animal feed and feed materials - trend analysis of monitoring results.

    Science.gov (United States)

    Adamse, Paulien; Van der Fels-Klerx, H J Ine; de Jong, Jacob

    2017-03-02

    This study aimed to obtain insights into the presence of cadmium, lead, mercury and arsenic in feed materials and feed over time, for the purpose of guiding national monitoring. Data from the Dutch feed monitoring program and from representatives of the feed industry in the period 2007-2013 were used. Data covered the concentrations of cadmium, lead, mercury and arsenic in a variety of feed materials and compound feeds in The Netherlands. Trends in the percentage of samples that exceeded the maximum limit (ML), set by the European Commission, and trends in average, median and 90(th) percentile concentrations of each of these elements per feed material or compound feed were investigated. Based on the results, monitoring for cadmium, lead, mercury and arsenic should focus on feed material of mineral origin, feed material of marine origin, especially fish meal, seaweed and algae as well as feed additives belonging to the functional groups of (i) trace elements (notably cupric sulphate, zinc oxide and manganese oxide for arsenic) and (ii) binders and anti-caking agents. Mycotoxin binders are a new group of feed additives that also need attention. For complementary feed it is important to make a proper distinction between mineral and non-mineral feed because the ML in the latter group is usually lower. In seaweed/algae products a relatively large number of samples contained arsenic concentrations that exceeded the ML. Forage crops in general do not need high priority in monitoring programs, although for arsenic grass meal still needs attention.

  6. Monitoring electro-magnetic field in urban areas: new set-ups and results

    Energy Technology Data Exchange (ETDEWEB)

    Lubritto, C.; Petraglia, A.; Paribello, G.; Formosi, R.; Rosa, M. de; Vetromile, C.; Palmieri, A.; D' Onofrio, A. [Seconda Universita di Napoli, Dipt. di Scienze Ambientali, Caserta (Italy); Di Bella, G.; Giannini, V. [Vector Group, Roma (Italy)

    2006-07-01

    In this paper two different set-ups for continuous monitoring of electromagnetic levels are presented: the first one (Continuous Time E.M.F. Monitoring System) is based upon a network of fixed stations, allowing a detailed field monitoring as function of the time; the second one (Mobile Measurements Units) resorts to portable stations mounted on standard bicycles, allowing a positional screening in limited time intervals. For both set-ups a particular attention has been paid to the data management, by means of tools like web geographic information systems (Web-Gis). Moreover the V.I.C.R.E.M./E.L.F. software has been used for a predictive analysis of the electromagnetic field levels along with the geo referenced data coming from the field measurements. Starting from these results it has been realized that there is a need for an efficient and correct action of monitoring and information/formation in this domain, where dis-information or bad information is very often spread in the population, in particular in a field where the process of the appreciation and assessment of risk does not necessarily make use of a rationale, technically-informed procedure, but the judgement is rather based on a personal feeling, which may derive from a limited, unstructured set of information, using a set of qualitative attributes rather than a quantity. (N.C.)

  7. Evaluation of using composite HPV genotyping assay results to monitor human papillomavirus infection burden through simulation

    OpenAIRE

    Lin, Carol Y.

    2015-01-01

    Background Researchers often group various HPV types into composite measures based on vaccine subtypes, oncogenic potential, or phylogenetic position. Composite prevalence estimates based on PCR genotyping assay results have been calculated to assess HPV infection burden and to monitor HPV vaccine effectiveness. While prevention and intervention strategies can be made based on these prevalence estimates, the discussion on how well these prevalence estimates measure the true underlying infecti...

  8. Optical-to-X-ray emission in low-absorption AGN: results from the Swift-BAT 9-month catalogue

    Science.gov (United States)

    Vasudevan, R. V.; Mushotzky, R. F.; Winter, L. M.; Fabian, A. C.

    2009-11-01

    We present simultaneous optical-to-X-ray spectral energy distributions (SEDs) from Swift's X-ray and UV-optical telescopes (XRTs and UVOTs) for a well-selected sample of 26 low-redshift (z extinction from the resultant nuclear SEDs. Black hole mass estimates are determined from the host galaxy Two-Micron All-Sky Survey K-band bulge luminosity. Accretion rates determined from our SEDs are on average low (Eddington ratios λEdd extinction. Significant dust reddening is found in some objects despite the selection of low NH objects, emphasizing the complex relationship between these two types of absorption. We do not find a correlation of the optical-to-X-ray spectral index with the Eddington ratio, regardless of the optical reference wavelength chosen for defining the spectral index. An anticorrelation of bolometric correction with black hole mass may reinforce `cosmic downsizing' scenarios, since the higher bolometric corrections at low mass would boost accretion rates in local, lower mass black holes. We also perform a basic analysis of the UVOT-derived host galaxy colours for our sample and find hosts cluster near the `green valley' of the colour-magnitude diagram, but better quality images are needed for a more definitive analysis. The low accretion rates and bolometric corrections found for this representative low-redshift sample are of particular importance for studies of AGN accretion history.

  9. Maternal mental health and its association with infant growth at 6 months in ethnic groups: results from the Born-in-Bradford birth cohort study.

    Directory of Open Access Journals (Sweden)

    Gemma D Traviss

    Full Text Available OBJECTIVE: To identify factors associated with infant growth up to 6 months, with a particular focus on maternal distress, and to explore the effect of ethnicity on any relation between maternal distress and infant growth. METHODS: Cohort study recruiting White and Pakistani women in the United Kingdom (UK. Infant growth was measured at birth and 6 months. Standard assessment of mental health (GHQ-28 was undertaken in pregnancy (26-28 weeks gestation and 6 months postpartum. Modelling included social deprivation, ethnicity, and other known influences on infant growth such as maternal smoking and alcohol consumption. RESULTS: Maternal distress improved markedly from pregnancy to 6 months postpartum. At both times Pakistani women had more somatic and depression symptoms than White women. Depression in pregnancy (GHQ subscale D was associated with lower infant growth at 6 months. Self-reported social dysfunction in pregnancy (GHQ subscale C was associated with lower gestational age.. Pakistani women reported higher GHQ scores during pregnancy associated with smaller infants at birth. They lived in areas of higher social deprivation, reported less alcohol consumption and smoking postnatally, all independent influences on growth at 6 months. CONCLUSIONS: Maternal mental health in pregnancy is an independent influence on infant growth up to 6 months and is associated with ethnicity which was itself associated with deprivation in our sample. There is a complex relationship between symptoms of maternal distress, ethnicity, deprivation, health behaviours, and early infant growth. Measures should include both emotional and somatic symptoms and interventions to reduce risks of poor early growth need to include psychological and social components.

  10. Results of Continuous Load Cell Monitoring Field Trial for UF6 Withdrawals at an Operating Industrial Plant

    Energy Technology Data Exchange (ETDEWEB)

    Krichinsky, Alan M [ORNL; Bell, Lisa S [ORNL; Conchewski, Curtis A [ORNL; Peters, Benjamin R [ORNL; Pickett, Chris A [ORNL; Richardson, Dave [ORNL; Rowe, Nathan C [ORNL; Younkin, James R [ORNL

    2010-01-01

    Continuous load cell monitoring (CLCM) has been implemented and tested for use as a safeguards tool during a 2009 field trial in an operating UF6 transfer facility. The transfer facility is part of the Portsmouth Gaseous Diffusion Plant in Piketon, Ohio, operated by the United States Enrichment Corporation. During the field trial, two process scales for UF{sub 6} cylinders were continuously monitored for a 6-month period as cylinders were being filled. The collected CLCM data were used in testing an event processor serving as a filter for highlighting measurements representing significant operational activities that are important in verifying declared operations. The collection of CLCM data, coupled with rules-based event processing, can provide inspectors with knowledge of a facility's feed and withdrawal activities occurring between site visits. Such process knowledge promises to enhance the effectiveness of safeguards by enabling inspectors to quantitatively compare declared activities directly with process measurements. Selected results of the field trial and event processing will be presented in the context of their value to an independent inspector and a facility operator.

  11. Blazar Monitoring at the Bell Observatory: Results from the First Two Years

    Science.gov (United States)

    Wills, W. L.; Carini, M. T.; Barnaby, D.; Atkerson, A.; Glass, D. A.; Monroe, T. R.; Ryle, W. T.

    2003-05-01

    Active galactic nuclei (AGN) are some of the most energetic objects in the Universe. They are composed of an ordinary elliptical galaxy with a super massive black hole at the center. An accretion disk surrounds the black hole while jets of material, moving at nearly relativistic speeds are emitted perpendicular to the disk. In the Blazar class of AGN jets are pointed almost directly along the line of sight, resulting in large amplitude, erratic brightness variations. Blazars are the most extreme examples of AGN with highly variable continuum emission as one of their defining characteristics. Our primary goal is the monitoring of the brightness variations of Blazars and using these variations to investigate the physics at work in these objects. The Bell Observatory has been used for the past two years to collect data to monitor these continuum variations. Undergraduate students run each observing session from either WKU's campus via the Internet or on-site. The telescope is equipped with a CCD camera, which is used to obtain images that are then transferred to WKU's campus where they are archived and analyzed by undergraduate students and faculty mentors. The results of the first two years of monitoring will be presented. Funding for this research was provided by NASA Kentucky Space Grant Consortium, NASA Kentucky EPSCoR Program, NSF EPSCoR Program, and the Applied Research and Technology Program at Western Kentucky University.

  12. Acoustic monitoring (RFM of total hip arthroplasty results of a cadaver study

    Directory of Open Access Journals (Sweden)

    Unger AC

    2009-06-01

    Full Text Available Abstract Introduction At present there are no reliable non-traumatic and non-invasive methods to analyse the healing process and loosening status after total hip replacement. Therefore early as well as late loosening of prosthesis and interface component problems are difficult to be found or diagnosed at any time. Methods In a cadaver study the potential application of Resonance Frequency Monitoring (RFM will be evaluated as a non-invasive and non-traumatic method to monitor loosening and interface problems in hip replacement. In a 65 year old female cadaver different stability scenarios for a total hip replacement (shaft, head/modular head and cup, ESKA, Luebeck, Germany are simulated in cemented and cement less prosthesis and then analysed with RFM. The types of stability vary from secure/press-fit to interface-shaft disruption. Results The RFM shows in cemented as well as cement less prosthesis significant intra-individual differences in the spectral measurements with a high dynamic (20 dB difference corresponding to the factor 100 (10000%, regarding the simulated status of stability in the prosthesis system. Conclusion The results of the study demonstrate RFM as a highly sensitive non-invasive and non-traumatic method to support the application of RFM as a hip prosthesis monitoring procedure. The data obtained shows the possibility to use RFM for osteointegration surveillance and early detection of interface problems, but will require further evaluation in clinical and experimental studies.

  13. Area Monitoring Dosimeter Program for the Pacific Northwest National Laboratory: Results for CY 2005

    Energy Technology Data Exchange (ETDEWEB)

    Bivins, Steven R.; Stoetzel, Gregory A.

    2006-06-21

    Pacific Northwest National Laboratory (PNNL) established an area monitoring dosimeter program in accordance with Article 514 of the Department of Energy (DOE) Radiological Control Manual (RCM) in January 1993. This program is to minimize the number of areas requiring issuance of personnel dosimeters and to demonstrate that doses outside Radiological Buffer Areas are negligible. In accordance with 10 CFR Part 835.402 (a)(1)-(4) and Article 511.1 of the PNNL Radiological Control Program Description, personnel dosimetry shall be provided to (1) radiological workers who are likely to receive at least 100 mrem annually, and (2) declared pregnant workers, minors, and members of the public who are likely to receive at least 50 mrem annually. Program results for calendar years 1993-2005 confirm that personnel dosimetry is not needed for individuals located in areas monitored by the program

  14. Area Monitoring Dosimeter Program for the Pacific Northwest National Laboratory: Results for CY 2001

    Energy Technology Data Exchange (ETDEWEB)

    Bivins, Steven R.; Stoetzel, Gregory A.

    2002-07-08

    Pacific Northwest National Laboratory (PNNL) established an area monitoring dosimeter program in accordance with Article 514 of the U.S. Department of Energy (DOE) Radiological Control Manual (RCM) in January 1993. This program is to minimize the number of areas requiring issuance of personnel dosimeters and to demonstrate that doses outside Radiological Buffer Areas are negligible. In accordance with 10 CFR Part 835.402 (a) (1)-(4) and Article 511.1 of the PNNL Radiological Control Program Description, personnel dosimetry shall be provided to 1) radiological workers who are likely to receive at least 100 mrem annually, and 2) declared pregnant workers, minors, and members of the public who are likely to receive at least 50 mrem annually. Program results for calendar years 1993-2001 confirm that personnel dosimetry is not needed for individuals located in areas monitored by the program.

  15. Area Monitoring Dosimeter Program for the Pacific Northwest National Laboratory: Results for CY 2006

    Energy Technology Data Exchange (ETDEWEB)

    Bivins, Steven R.; Stoetzel, Gregory A.

    2007-07-19

    Pacific Northwest National Laboratory (PNNL) established an area monitoring dosimeter program in accordance with Article 514 of the Department of Energy (DOE) Radiological Control Manual (RCM) in January 1993. This program is to minimize the number of areas requiring issuance of personnel dosimeters and to demonstrate that doses outside Radiological Buffer Areas are negligible. In accordance with 10 CFR Part 835.402 (a)(1)-(4) and Article 511.1 of the PNNL Radiological Control Program Description, personnel dosimetry shall be provided to 1) radiological workers who are likely to receive at least 100 mrem annually, and 2) declared pregnant workers, minors, and members of the public who are likely to receive at least 50 mrem annually. Program results for calendar years 1993-2005 confirm that personnel dosimetry is not needed for individuals located in areas monitored by the program.

  16. Area Monitoring Dosimeter Program for the Pacific Northwest National Laboratory: Results for CY 2000

    Energy Technology Data Exchange (ETDEWEB)

    Bivins, Steven R.; Stoetzel, Gregory A.

    2001-07-05

    Pacific Northwest National Laboratory (PNNL) established an area monitoring dosimeter program in accordance with Article 514 of the Department of Energy (DOE) Radiological Control Manual (RCM) in January 1993. This program is to minimize the number of areas requiring issuance of personnel dosimeters and to demonstrate that doses outside Radiological Buffer Areas are negligible. In accordance with 10 CFR Part 835.402 (a) (1)-(4) and Article 511.1 of the DOE Standard Radiological Control, personnel dosimetry shall be provided to 1) radiological workers who are likely to receive at least 100 mrem annually, and 2) declared pregnant workers, minors, and members of the public who are likely to receive at least 50 mrem annually. Program results for calendar years 1993-2000 confirm that personnel dosimetry is not needed for individuals located in areas monitored by the program.

  17. Catheter-based renal denervation for resistant hypertension: 12-month results of the EnligHTN I first-in-human study using a multielectrode ablation system.

    Science.gov (United States)

    Papademetriou, Vasilios; Tsioufis, Costas P; Sinhal, Ajay; Chew, Derek P; Meredith, Ian T; Malaiapan, Yuvi; Worthley, Matthew I; Worthley, Stephen G

    2014-09-01

    Renal denervation has emerged as a novel approach for the treatment of patients with drug-resistant hypertension. To date, only limited data have been published using multielectrode radiofrequency ablation systems. In this article, we present the 12-month data of EnligHTN I, a first-in-human study using a multielectrode ablation catheter. EnligHTN I enrolled 46 patients (average age, 60±10 years; on average 4.7±1.0 medications) with drug-resistant hypertension. Eligible patients were on ≥3 antihypertensive medications and had a systolic blood pressure (BP) ≥160 mm Hg (≥150 mm Hg for diabetics). Bilateral renal artery ablation was performed using a percutaneous femoral approach and standardized techniques. The average baseline office BP was 176/96 mm Hg, average 24-hour ambulatory BP was 150/83 mm Hg, and average home BP was 158/90 mm Hg. The average reductions (mm Hg) at 1, 3, 6, and 12 months were as follows: office: -28/-10, -27/-10, -26/-10, and -27/-11 mm Hg (Phypertension. Home BP measurements parallel measurements obtained with 24-hour ambulatory monitoring.

  18. Monitoring of radiation in the environment in the Netherlands. Results in 2000

    CERN Document Server

    Knetsch, G J

    2002-01-01

    This report presents the results of radioactivity measurements in the environment in the Netherlands carried out by RIVM, RIZA, RIKZ and Inspectorate for Health Protection and Veterinary Public Health in 2000. Measurements of radioactivity have been carried out in airborne particulates, deposition, surface water, seawater, drinking water and food (honey, game, blueberry and mushrooms). Results for ambient dose equivalent rates have been obtained from the National Radioactivity Monitoring Network. No measurements were done in milk. In 2000 no elevated levels of radioactivity were found in the Dutch environment

  19. Monitoring of radiation in the environment in the Netherlands. Results in 2000

    Energy Technology Data Exchange (ETDEWEB)

    Knetsch, G.J. (ed.)

    2002-07-01

    This report presents the results of radioactivity measurements in the environment in the Netherlands carried out by RIVM, RIZA, RIKZ and Inspectorate for Health Protection and Veterinary Public Health in 2000. Measurements of radioactivity have been carried out in airborne particulates, deposition, surface water, seawater, drinking water and food (honey, game, blueberry and mushrooms). Results for ambient dose equivalent rates have been obtained from the National Radioactivity Monitoring Network. No measurements were done in milk. In 2000 no elevated levels of radioactivity were found in the Dutch environment.

  20. Transboundary Air Pollution over the Central Himalayas: Monitoring network and Preliminary Results

    Science.gov (United States)

    Zhang, Qianggong; Kang, Shichang

    2016-04-01

    The Himalayas, stretching over 3000 kms along west-east, separates South Asia continent and the Tibetan Plateau with its extreme high altitudes. The South Asia is being increasingly recognized to be among the hotspots of air pollution, posing multi-effects on regional climate and environment. Recent monitoring and projection have indicated an accelerated decrease of glacier and increasing glacier runoff in the Himalayas, and a remarkable phenomenon has been recognized in the Himalayas that long-range transport atmospheric pollutants (e.g., black carbon and dust) deposited on glacier surface can promote glacier melt, and in turns, may liberate historical contaminant legacy in glaciers into downward ecosystems. To understand the air pollution variation and how they can infiltrate the Himalayas and beyond, we started to operate a coordinated atmospheric pollution monitoring network composing 11 sites with 5 in Nepal and 6 in Tibet since April 2013. Atmospheric total suspended particles ( TSP air mass trajectories suggested that the transboundary air pollution over the Himalayas is episodic and is likely concentrated in pre-monsoon seasons. Our results emphasis the potential transport and impact of air pollution from South Asia to Himalayas and further inland Tibetan Plateau. The monitoring network will be continuously operated to provide basis for defining the transboundary air pollution and their impact on the environments and ecosystems over the Himalayas and the Tibetan Plateau.

  1. Results of groundwater monitoring and vegetation sampling at Everest, Kansas, in 2009 .

    Energy Technology Data Exchange (ETDEWEB)

    LaFreniere, L. M.; Environmental Science Division

    2010-05-13

    In April 2008, the Commodity Credit Corporation of the U.S. Department of Agriculture (CCC/USDA) conducted groundwater sampling for the analysis of volatile organic compounds (VOCs) in the existing network of monitoring points at Everest, Kansas (Argonne 2008). The objective of the 2008 investigation was to monitor the distribution of carbon tetrachloride contamination in groundwater previously identified in CCC/USDA site characterization and groundwater sampling studies at Everest in 2000-2006 (Argonne 2001, 2003, 2006a,b). The work at Everest is being undertaken on behalf of the CCC/USDA by Argonne National Laboratory, under the oversight of the Kansas Department of Health and Environment (KDHE). The findings of the 2008 investigation were as follows: (1) Measurements of groundwater levels obtained manually and through the use of automatic recorders demonstrated a consistent pattern of groundwater flow - and inferred contaminant migration - to the north-northwest from the former CCC/USDA facility toward the Nigh property, and then west-southwest from the Nigh property toward the intermittent creek that lies west of the former CCC/USDA facility and the Nigh property. (2) The range of concentrations and the areal distribution of carbon tetrachloride identified in the groundwater at Everest in April 2008 were generally consistent with previous results. The results of the 2008 sampling (reflecting the period from 2006 to 2008) and the earlier investigations at Everest (representing the period from 2000 to 2006) show that no significant downgradient extension of the carbon tetrachloride plume occurred from 2000 to 2008. (3) The slow contaminant migration indicated by the monitoring data is qualitatively consistent with the low groundwater flow rates in the Everest aquifer unit estimated previously on the basis of site-specific hydraulic testing (Argonne 2006a,b). (4) The April 2008 and earlier sampling results demonstrate that the limits of the plume have been

  2. 2015 Long-Term Hydrologic Monitoring Program Sampling and Analysis Results Report for Project Rulison, Co

    Energy Technology Data Exchange (ETDEWEB)

    Findlay, Rick [Navarro Research and Engineering, Oak Ridge, TN (United States); Kautsky, Mark [US Department of Energy, Washington, DC (United States). Office of Legacy Management

    2015-12-01

    The U.S. Department of Energy (DOE) Office of Legacy Management conducted annual sampling at the Rulison, Colorado, Site for the Long-Term Hydrologic Monitoring Program (LTHMP) on May 20–22 and 27, 2015. Several of the land owners were not available to allow access to their respective properties, which created the need for several sample collection trips. This report documents the analytical results of the Rulison monitoring event and includes the trip report and the data validation package (Appendix A). The groundwater and surface water monitoring were shipped to the GEL Group Inc. laboratories for analysis. All requested analyses were successfully completed. Samples were analyzed for gamma-emitting radionuclides by high- resolution gamma spectrometry. Tritium was analyzed using two methods, the conventional tritium method, which has a detection limit on the order of 400 picocuries per liter (pCi/L), and the enriched method (for selected samples), which has a detection limit on the order of 3 pCi/L.

  3. 2015 Long-Term Hydrologic Monitoring Program Sampling and Analysis Results at Rio Blanco, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    Findlay, Rick [Nararro Research and Engineering, Oak Ridge, TN (United States); Kautsky, Mark [US Department of Energy, Washington, DC (United States). Office of Legacy Management

    2015-12-01

    The U.S. Department of Energy (DOE) Office of Legacy Management conducted annual sampling at the Rio Blanco, Colorado, Site for the Long-Term Hydrologic Monitoring Program (LTHMP) on May 20–21, 2015. This report documents the analytical results of the Rio Blanco annual monitoring event, the trip report, and the data validation package. The groundwater and surface water monitoring samples were shipped to the GEL Group Inc. laboratories for conventional analysis of tritium and analysis of gamma-emitting radionuclides by high-resolution gamma spectrometry. A subset of water samples collected from wells near the Rio Blanco site was also sent to GEL Group Inc. for enriched tritium analysis. All requested analyses were successfully completed. Samples were collected from a total of four onsite wells, including two that are privately owned. Samples were also collected from two additional private wells at nearby locations and from nine surface water locations. Samples were analyzed for gamma-emitting radionuclides by high-resolution gamma spectrometry, and they were analyzed for tritium using the conventional method with a detection limit on the order of 400 picocuries per liter (pCi/L). Four locations (one well and three surface locations) were analyzed using the enriched tritium method, which has a detection limit on the order of 3 pCi/L. The enriched locations included the well at the Brennan Windmill and surface locations at CER-1, CER-4, and Fawn Creek 500 feet upstream.

  4. Monitoring system for a synthesizer at SPring-8 synchrotron radiation facility and obtained results

    Energy Technology Data Exchange (ETDEWEB)

    Kawashima, Y., E-mail: ykawashima@bnl.gov [Brookhaven National Laboratory, PS, Bldg. 817, Upton, NY 11973 (United States); Ego, H. [JASRI/SPring-8, 1-1-1, Kouto, Sayo-gun, Hyogo 679-5198 (Japan); Hara, M. [RIKEN, 2-1, Hirosawa, Wako, Saitama 351-0198 (Japan); Ohashi, Y.; Ohshima, T.; Takao, M.; Takashima, T. [JASRI/SPring-8, 1-1-1, Kouto, Sayo-gun, Hyogo 679-5198 (Japan)

    2013-02-11

    Beam orbit distortion in all dispersive sections was observed in the SPring-8 storage ring during beam commissioning. In order to confirm the stability of the radio frequency (RF) synthesizer, a monitoring system was developed. The system consists of a frequency counter referenced to a global positioning system (GPS) receiver. With this system, the output of the synthesizer, which uses an external 10 MHz-Rubidium atomic clock with the time accuracy of Δt/t=10{sup −12}, is correctly monitored with 11 digits absolute accuracy, verifying that the synthesizer works well. Measurement of the circumference of the SPring-8 storage ring reveals the effect of tidal forces and seasonal temperature variations on beam orbit. To maintain the center axis of photon radiation in experimental beam lines, a beam energy correction is carried out. The frequency of the RF synthesizer is changed every 5 min with 10-digit accuracy. This corresponds to an energy accuracy of ΔE/E=1.16×10{sup −6}. The monitoring system for the synthesizer and obtained results are described.

  5. First Results from Contamination Monitoring with the WFC3 UVIS G280 Grism

    Science.gov (United States)

    Rothberg, B.; Pirzkal, N.; Baggett, S.

    2011-11-01

    The presence of contaminants within the optical light path of the instrument or telescope can alter photometric zeropoints and the observed flux levels of imaging and spectra, particularly at UV wavelengths. Regular monitoring of a spectro-photometric standard star using photometric filters has been used in the past to monitor the presence of contaminants and (when necessary) re-calibrate zeropoints. However, the use of the WFC3 UVIS Grism mode (G280 filter) may provide a more robust early alert detection system for the presence of contaminants, in particular, those that are photo-polymerized from the bright Earth. These contaminants may collect on surfaces in the optical light path of the telescope. The G280 grism is sensitive to light at wavelengths below the cutoff of the bluest UV filter (F218W). In this ISR, we present: 1) the first results from G280 monitoring for the period of 2010-November through 2011-August; 2) the discovery of an anomaly in the WCS header information of sub-array exposures; and 3) an outline for reducing standard G280 grism observations and the specialized case of observations obtained in sub-array mode.

  6. Feasibility Study of a Rotorcraft Health and Usage Monitoring System (HUMS): Results of Operator's Evaluation

    Science.gov (United States)

    Romero, Raylund; Summers, Harold; Cronkhite, James

    1996-01-01

    The objective was to evaluate the feasibility of a state-of-the-art health and usage monitoring system (HUMS) to provide monitoring of critical mechanical systems on the helicopter, including motors, drive train, engines, and life-limited components. The implementation of HUMS and cost integration with current maintenance procedures was assessed from the operator's viewpoint in order to achieve expected benefits from these systems, such as enhanced safety, reduced maintenance cost, and increased availability. An operational HUMS that was installed and operated under an independent flight trial program was used as a basis for this study. The HUMS equipment and software were commercially available. Based on the results of the feasibility study, the HUMS used in the flight trial program generally demonstrated a high level of reliability in monitoring the rotor system, engines, drive train, and life-limited components. The system acted as a sentinel to warn of impending failures. A worn tail rotor pitch bearing was detected by HUMS, which had the capability for self testing to diagnose system and sensor faults. Examples of potential payback to the operator with HUMS were identified, including reduced insurance cost through enhanced safety, lower operating costs derived from maintenance credits, increased aircraft availability, and improved operating efficiency. The interfacing of HUMS with current operational procedures was assessed to require only minimal revisions to the operator's maintenance manuals. Finally the success in realizing the potential benefits from HUMS technology was found to depend on the operator, helicopter manufacturer, regulator (FAA), and HUMS supplier working together.

  7. Exploratory X-ray monitoring of luminous radio-quiet quasars at high redshift: Initial results

    Energy Technology Data Exchange (ETDEWEB)

    Shemmer, Ohad; Stein, Matthew S. [Department of Physics, University of North Texas, Denton, TX 76203 (United States); Brandt, W. N.; Schneider, Donald P. [Department of Astronomy and Astrophysics, The Pennsylvania State University, University Park, PA 16802 (United States); Paolillo, Maurizio [Dipartimento di Scienze Fisiche, Università Federico II di Napoli, via Cinthia 6, I-80126 Napoli (Italy); Kaspi, Shai [School of Physics and Astronomy and the Wise Observatory, Tel Aviv University, Tel Aviv 69978 (Israel); Vignali, Cristian [Dipartimento di Astronomia, Università degli studi di Bologna, via Ranzani 1, I-40127 Bologna (Italy); Lira, Paulina [Departamento de Astronomia, Universidad de Chile, Camino del Observatorio 1515, Santiago (Chile); Gibson, Robert R., E-mail: ohad@unt.edu [Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195 (United States)

    2014-03-10

    We present initial results from an exploratory X-ray monitoring project of two groups of comparably luminous radio-quiet quasars (RQQs). The first consists of four sources at 4.10 ≤ z ≤ 4.35, monitored by Chandra, and the second is a comparison sample of three sources at 1.33 ≤ z ≤ 2.74, monitored by Swift. Together with archival X-ray data, the total rest-frame temporal baseline spans ∼2-4 yr and ∼5-13 yr for the first and second group, respectively. Six of these sources show significant X-ray variability over rest-frame timescales of ∼10{sup 2}-10{sup 3} days; three of these also show significant X-ray variability on rest-frame timescales of ∼1-10 days. The X-ray variability properties of our variable sources are similar to those exhibited by nearby and far less luminous active galactic nuclei (AGNs). While we do not directly detect a trend of increasing X-ray variability with redshift, we do confirm previous reports of luminous AGNs exhibiting X-ray variability above that expected from their luminosities, based on simplistic extrapolation from lower luminosity sources. This result may be attributed to luminous sources at the highest redshifts having relatively high accretion rates. Complementary UV-optical monitoring of our sources shows that variations in their optical-X-ray spectral energy distribution are dominated by the X-ray variations. We confirm previous reports of X-ray spectral variations in one of our sources, HS 1700+6416, but do not detect such variations in any of our other sources in spite of X-ray flux variations of up to a factor of ∼4. This project is designed to provide a basic assessment of the X-ray variability properties of RQQs at the highest accessible redshifts that will serve as a benchmark for more systematic monitoring of such sources with future X-ray missions.

  8. Changes in skinfold thickness and waist circumference after 12 and 24 months resulting from the NHF-NRG In Balance-project

    Directory of Open Access Journals (Sweden)

    Visscher Tommy LS

    2010-04-01

    Full Text Available Abstract Background More knowledge is needed regarding the effectiveness of weight gain prevention programmes. The present study tested the 12-and 24-month effectiveness of the 'Netherlands Research programme weight Gain prevention' (NHF-NRG-In Balance-project, a worksite-based intervention aimed at the prevention of weight gain. Methods Twelve worksites (n = 553 participants were matched and assigned to either intervention or control group. The worksites and employees of the intervention group received individual (i.e. pedometer, computer-tailored advice and environmental (i.e. changes in worksite canteen interventions, directed at physical activity and food intake over 1-year. Differences between the intervention and control group in changes in body weight, BMI, skinfold thickness and waist circumference at 12 and 24 months were examined using multilevel linear regression analyses adjusting for various baseline characteristics (age, gender, BMI, marital status, education and smoking status. Results A significant greater reduction in skinfold thickness was found in the intervention group than in the control group, both after 12-and 24 months (Unstandardized regression coefficients (B = -2.52, 95% C.I. -4.58, -0.45; p = 0.018; B = -4.83, 95% C.I. 6.98, -2.67; p Conclusions The project was effective with regard to changes in skinfold thickness and waist circumference both at 12 and 24 months. It supports the usefulness of worksite-based prevention, especially regarding maintenance of behavioral changes.

  9. Evaluation of using composite HPV genotyping assay results to monitor human papillomavirus infection burden through simulation.

    Science.gov (United States)

    Lin, Carol Y

    2015-03-12

    Researchers often group various HPV types into composite measures based on vaccine subtypes, oncogenic potential, or phylogenetic position. Composite prevalence estimates based on PCR genotyping assay results have been calculated to assess HPV infection burden and to monitor HPV vaccine effectiveness. While prevention and intervention strategies can be made based on these prevalence estimates, the discussion on how well these prevalence estimates measure the true underlying infection burdens is limited. A simulation study was conducted to evaluate accuracy of using composite genotyping assay results to monitor HPV infection burden. Data were generated based on mathematical algorithms with prespecified type-specific infection burdens, assay sensitivity, specificity, and correlations between various HPV types. Estimated-to-true prevalence rate ratios and percent reduction of vaccine types were calculated. When "true" underlying type-specific infection burdens were prespecified as the reported prevalence in U.S. and genotyping assay with sensitivity and specificity (0.95, 0.95) was used, estimated-to-true infection prevalence ratios were 2.35, 2.29, 2.18, and 1.46, for the composite measures with 2 high-risk vaccine, 4 vaccine, 14 high-risk and 37 HPV types, respectively. Estimated-to-true prevalence ratios increased when prespecified "true" underlying infection burdens or assay specificity declined. When prespecified "true" type-specific infections of HPV 6, 11, 16 and 18 were reduced by 50%, the composite prevalence estimate of 4 vaccine types only decreased by 17% which is much lower than 48% reduction in the prespecified "true" composite prevalence. Composite prevalence estimates calculated based on panels of genotyping assay results generally over-estimate the "true" underlying infection burdens and could under-estimate vaccine effectiveness. Analytical specificity of genotyping assay is as or more important than analytical sensitivity and should be considered in

  10. A 3-Month Randomized Controlled Pilot Trial of a Patient-Centered, Computer-Based Self-Monitoring System for the Care of Type 2 Diabetes Mellitus and Hypertension.

    Science.gov (United States)

    Or, Calvin; Tao, Da

    2016-04-01

    This study was performed to evaluate the effects of a patient-centered, tablet computer-based self-monitoring system for chronic disease care. A 3-month randomized controlled pilot trial was conducted to compare the use of a computer-based self-monitoring system in disease self-care (intervention group; n = 33) with a conventional self-monitoring method (control group; n = 30) in patients with type 2 diabetes mellitus and/or hypertension. The system was equipped with a 2-in-1 blood glucose and blood pressure monitor, a reminder feature, and video-based educational materials for the care of the two chronic diseases. The control patients were given only the 2-in-1 monitor for self-monitoring. The outcomes reported here included the glycated hemoglobin (HbA1c) level, fasting blood glucose level, systolic blood pressure, diastolic blood pressure, chronic disease knowledge, and frequency of self-monitoring. The data were collected at baseline and at 1-, 2-, and 3-month follow-up visits. The patients in the intervention group had a significant decrease in mean systolic blood pressure from baseline to 1 month (p diabetes control. The beneficial effects of the use of electronic self-care resources and support provided via mobile technologies require further confirmation in longer-term, larger trials.

  11. Photometric Monitoring of Active Galactic Nuclei in the Center for Automated Space Science: Preliminary Results

    Science.gov (United States)

    Culler, Ryan; Deckard, Monica; Guilaran, Fonsie; Watson, Casey; Carini, Michael; Gelderman, Richard; Neely, William

    1997-02-01

    In this paper, we will present preliminary results of our program to photometrically monitor a set of Active Galactic Nuclei (AGN) known as Blazars. Using CCDs as N-star photometers and a technique known as aperture photometry, we can achieve close to 0.02 magnitude precision with small to midsize telescopes. Blazars are highly luminous and highly variable; studying these variations provides insight into the central engines producing the high luminosities. we report on our reduction and analysis of CCD data obtained at one of our collaborating institutions, the NF Observatory at Western New Mexico University. CCD data obtained at the Western Kentucky University 24 inch telescope will also be discussed.

  12. Electrochromic windows for commercial buildings: Monitored results from a full-scale testbed

    OpenAIRE

    Eleanor S. Lee; DiBartolomeo, Dennis L.; Selkowitz, Stephen E.

    2000-01-01

    Electrochromic glazings promise to be the next major advance in energy-efficient window technology, helping to transform windows and skylights from an energy liability to an energy source for the nation's building stock. Monitored results from a full-scale demonstration of large-area electrochromic windows are given. The test consisted of two side-by-side, 3.7x4.6-m, office-like rooms. In each room, five 62x173-cm lower electrochromic windows and five 62x43-cm upper electrochromic windo...

  13. First test results of a high-speed beam conditions monitor for the ATLAS experiment

    CERN Document Server

    Pernegger, Heinz

    2004-01-01

    The paper presents the design and first test results of the high- speed beam conditions monitor (BCM) for the ATLAS experiment at the large hadron collider (LHC). The goal of the BCM is to monitor instantaneous rates of collision and background and detect signs of beam instabilities. The detector is based on polycrystalline chemical-vapor-deposition (pCVD) diamond as active sensor material. We have chosen this detector material for its proven radiation hardness and fast signal properties. For the readout of the diamonds we developed front-end readout electronics based on high-bandwidth RF amplifiers. The signal response of the amplifier has been optimized for the ionization current signal of pCVD diamond in order to achieve a signal risetime of results which were obtained on prototype assemblies in source tests and test beam. The obtained results demonstrate the feasibility of such a detector system for the ATLAS BCM. The tests yield BCM signals w...

  14. UAV-based landslide deformation monitoring - first results from Corvara landslide

    Science.gov (United States)

    Thiebes, Benni; Tomelleri, Enrico; Mejia-Aguilar, Abraham; Schlögel, Romy; Darvishi, Mehdi; Remondino, Fabio; Toschi, Isabella; Rutzinger, Martin; Zieher, Thomas

    2016-04-01

    In recent years, unmanned aerial vehicles (UAVs) have been more frequently utilised to study geomorphological and natural hazard processes, including gravitational mass movements such as landslides. UAVs can be equipped with different sensors, e.g. photo cameras and laser scanners, and the data that can be achieved can substantially improve the monitoring and understanding of the involved natural processes. One of the main advantages of UAVs is their flexibility that allows for carrying out assessments of large areas in short periods of time and at much lower costs than other platforms, e.g. airplanes or helicopters. Thereby, UAVs represent an interesting technique to complement more traditional monitoring methods. Here we present some first results of the EUREGIO-funded LEMONADE project that is concerned with the combination and integration of novel and traditional landslide monitoring techniques. We carried out a series of UAV flights over a particularly active part of the Corvara landslide and acquired aerial imagery for quantitative assessments of the retrogressive enlargement of the landslide over recent years. Additional field surveys including terrestrial laser scanning, and UAV-based photogrammetry and laser scanning are scheduled for summer 2016. The Corvara landslide is a large complex earthflow in the Italian Dolomites that has been investigated by a wide range of methodologies over the past years. The landslide is characterised by movement patterns of greatly varying magnitude, ranging from annual rates of a few cm to more than 20 m. The current and past monitoring activities concentrated on GPS measurements as well as multi-temporal differential radar interferometry utilising artificial corner reflectors. Thereby, primarily punctual displacement data were achieved and spatial information on topographic and geomorphic changes were consequently sparse. For our photogrammetry study, we utilised a SoLeon octocopter equipped with a Ricoh GR 16.2 Megapixels

  15. Investigating volcanic hazard in Cape Verde Islands through geophysical monitoring: network description and first results

    Science.gov (United States)

    Faria, B.; Fonseca, J. F. B. D.

    2014-02-01

    We describe a new geophysical network deployed in the Cape Verde Archipelago for the assessment and monitoring of volcanic hazards as well as the first results from the network. Across the archipelago, the ages of volcanic activity range from ca. 20 Ma to present. In general, older islands are in the east and younger ones are in the west, but there is no clear age progression of eruptive activity as widely separated islands have erupted contemporaneously on geological timescales. The overall magmatic rate is low, and there are indications that eruptive activity is episodic, with intervals between episodes of intense activity ranging from 1 to 4 Ma. Although only Fogo Island has experienced eruptions (mainly effusive) in the historic period (last 550 yr), Brava and Santo Antão have experienced numerous geologically recent eruptions, including violent explosive eruptions, and show felt seismic activity and geothermal activity. Evidence for recent volcanism in the other islands is more limited and the emphasis has therefore been on monitoring of the three critical islands of Fogo, Brava and Santo Antão, where volcanic hazard levels are highest. Geophysical monitoring of all three islands is now in operation. The first results show that on Fogo, the seismic activity is dominated by hydrothermal events and volcano-tectonic events that may be related to settling of the edifice after the 1995 eruption; in Brava by volcano-tectonic events (mostly offshore), and in Santo Antão by volcano-tectonic events, medium-frequency events and harmonic tremor. Both in Brava and in Santo Antão, the recorded seismicity indicates that relatively shallow magmatic systems are present and causing deformation of the edifices that may include episodes of dike intrusion.

  16. RESULTS OF TRITIUM TRACKING AND GROUNDWATER MONITORING AT THE HANFORD SITE 200 AREA STATE APPROVED LAND DISPOSAL SITE FY2008

    Energy Technology Data Exchange (ETDEWEB)

    ERB DB

    2008-11-19

    The Hanford Site's 200 Area Effluent Treatment Facility (ETF) processes contaminated aqueous wastes derived from Hanford Site facilities. The treated wastewater occasionally contains tritium, which cannot be removed by the ETF prior to the wastewater being discharged to the 200 Area State-Approved Land Disposal Site (SALDS). During the first 11 months of fiscal year 2008 (FY08) (September 1, 2007, to July 31, 2008), approximately 75.15 million L (19.85 million gal) of water were discharged to the SALDS. Groundwater monitoring for tritium and other constituents, as well as water-level measurements, is required for the SALDS by State Waste Discharge Permit Number ST-4500 (Ecology 2000). The current monitoring network consists of three proximal (compliance) monitoring wells and nine tritium-tracking wells. Quarterly sampling of the proximal wells occurred in October 2007 and in January/February 2008, April 2008, and August 2008. The nine tritium-tracking wells, including groundwater monitoring wells located upgradient and downgradient of the SALDS, were sampled in January through April 2008. Water-level measurements taken in the three proximal SALDS wells indicate that a small groundwater mound is present beneath the facility, which is a result of operational discharges. The mound increased in FY08 due to increased ETF discharges from treating groundwater from extraction wells at the 200-UP-l Operable Unit and the 241-T Tank Farm. Maximum tritium activities increased by an order of magnitude at well 699-48-77A (to 820,000 pCi/L in April 2008) but remained unchanged in the other two proximal wells. The increase was due to higher quantities of tritium in wastewaters that were treated and discharged in FY07 beginning to appear at the proximal wells. The FY08 tritium activities for the other two proximal wells were 68,000 pCi/L at well 699-48-77C (October 2007) and 120,000 pCi/L at well 699-48-77D (October 2007). To date, no indications of a tritium incursion from

  17. Movardol® (N-acetylglucosamine, Boswellia serrata, ginger) supplementation in the management of knee osteoarthritis: preliminary results from a 6-month registry study.

    Science.gov (United States)

    Bolognesi, G; Belcaro, G; Feragalli, B; Cornelli, U; Cotellese, R; Hu, S; Dugall, M

    2016-12-01

    Knee Osteoarthritis (OA) is a chronic disease caused by the deterioration of cartilage in joints, which results in activation of the inflammatory response, pain, and impaired movement. Complementary therapies, particularly supplementation, in the management of moderate/severe knee OA have been gaining attention. This registry study aimed at evaluating the synergistic effect of Movardol®, a supplementation containing active ingredients with recognized anti-inflammatory activities on symptoms and levels of circulating biomarkers of knee OA. 54 subjects with symptomatic, moderate knee OA freely decided to follow either a standard management (SM) (n = 26) or SM plus oral supplementation with Movardol® (n = 28). Movardol® supplementation containing N-acetyl-D-glucosamine, ginger, and Boswellia Serrata extract was taken at the following dosage: 3 tablets/day for one week and then 2 tablets/day. Several parameters were assessed at inclusion and after 1, 3 and 6 months: functional impairment by the Karnofsky Performance Scale Index; pain, stiffness, physical, social and emotional functions by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC); total and pain-free walking distance; circulating biomarkers of inflammation and oxidative stress. Significant improvements in the functional outcomes and pain-free walking distance were observed after 1, 3 and 6 months in OA patients supplemented with Movardol®. Moreover, all the signs/symptoms of disease assessed by the WOMAC tended to regress over a 6-month period in patients following SM+supplementation. Inflammatory markers and plasmatic content of reactive oxygen species decreased over 6 months, in supplemented patients. Movardol® supplementation resulted to be safe and well tolerated, also showing the beneficial effect in term of a decrease in pharmacological and non-pharmacological treatments and, consequently, reduction in management costs. These preliminary results indicate the efficacy and

  18. PRIMARY RESULTS OF LONG-TERM DYNAMIC MONITORING OF CHILDREN WITH BRONCHIAL ASTHMA OF UNCONTROLLED SEVERE PERSISTENT COURSE

    Directory of Open Access Journals (Sweden)

    L. S. Namazova-Baranova

    2016-01-01

    Full Text Available Background. Patients registers help obtain the latest information about the clinical course of a disease, safety and effectiveness of the medical technology. Objective: Our aim was to analyze the efficiency and safety of omalizumab with children suffering from uncontrolled severe persistent bronchial asthma (BA according to the data of the developed register. Methods.  A register of patients with severe asthma of uncontrolled course receiving omalizumab in addition to basic therapy has been developed. Results. Results of treatment of 101 children aged 6–17 have been analyzed. The duration of therapy with omalizumab lasted from 1 to 85 months, with a median of 16 (10; 44 months. The drug was used in doses of 75 to 600 mg, with a median of 300 (225; 375 mg. The therapy with omalizumab allowed achieving a better control of the disease (AST test prior to start of therapy — 14 (11; 17 points, in 1 year — 20 (13; 25; p < 0,001; reduction of the volume of daily base therapy (prior to start of therapy, average dose of inhaled corticosteroids in terms of fluticasone was 629 ± 304 mg (n = 15, in 4 years — 524 ± 342 mg; p = 0.065; reduction of the number of aggravations and the need to use short-effectiv   2-agonists.  No adverse systemic effects of the introduction of genetically engineered biological drugs have been found. Conclusion. Register of patients with severe persistent asthma can be used as a tool for long-term  monitoring and integrated assessment of the efficiency and safety of therapy.

  19. Infrared Thermography for Monitoring of Freeze-Drying Processes: Instrumental Developments and Preliminary Results

    Science.gov (United States)

    Emteborg, Håkan; Zeleny, Reinhard; Charoud-Got, Jean; Martos, Gustavo; Lüddeke, Jörg; Schellin, Holger; Teipel, Katharina

    2014-01-01

    Coupling an infrared (IR) camera to a freeze dryer for on-line monitoring of freeze-drying cycles is described for the first time. Normally, product temperature is measured using a few invasive Pt-100 probes, resulting in poor spatial resolution. To overcome this, an IR camera was placed on a process-scale freeze dryer. Imaging took place every 120 s through a Germanium window comprising 30,000 measurement points obtained contact-free from −40°C to 25°C. Results are presented for an empty system, bulk drying of cheese slurry, and drying of 1 mL human serum in 150 vials. During freezing of the empty system, differences of more than 5°C were measured on the shelf. Adding a tray to the empty system, a difference of more than 8°C was observed. These temperature differences probably cause different ice structures affecting the drying speed during sublimation. A temperature difference of maximum 13°C was observed in bulk mode during sublimation. When drying in vials, differences of more than 10°C were observed. Gradually, the large temperature differences disappeared during secondary drying and products were transformed into uniformly dry cakes. The experimental data show that the IR camera is a highly versatile on-line monitoring tool for different kinds of freeze-drying processes. © 2014 European Union 103:2088–2097, 2014 PMID:24902839

  20. Air Monitoring Network at Tonopah Test Range: Network Description, Capabilities, and Analytical Results

    Energy Technology Data Exchange (ETDEWEB)

    Hartwell, William T.; Daniels, Jeffrey; Nikolich, George; Shadel, Craig; Giles, Ken; Karr, Lynn; Kluesner, Tammy

    2012-01-01

    During the period April to June 2008, at the behest of the Department of Energy (DOE), National Nuclear Security Administration, Nevada Site Office (NNSA/NSO); the Desert Research Institute (DRI) constructed and deployed two portable environmental monitoring stations at the Tonopah Test Range (TTR) as part of the Environmental Restoration Project Soils Activity. DRI has operated these stations since that time. A third station was deployed in the period May to September 2011. The TTR is located within the northwest corner of the Nevada Test and Training Range (NTTR), and covers an area of approximately 725.20 km2 (280 mi2). The primary objective of the monitoring stations is to evaluate whether and under what conditions there is wind transport of radiological contaminants from Soils Corrective Action Units (CAUs) associated with Operation Roller Coaster on TTR. Operation Roller Coaster was a series of tests, conducted in 1963, designed to examine the stability and dispersal of plutonium in storage and transportation accidents. These tests did not result in any nuclear explosive yield. However, the tests did result in the dispersal of plutonium and contamination of surface soils in the surrounding area.

  1. Laser Spectroscopy Multi-Gas Monitor: Results of Technology Demonstration on ISS

    Science.gov (United States)

    Mudgett, Paul D.; Pilgrim, Jeffrey S.

    2015-01-01

    Tunable diode laser spectroscopy (TDLS) is an up and coming trace and major gas monitoring technology with unmatched selectivity, range and stability. The technology demonstration of the 4 gas Multi-Gas Monitor (MGM), reported at the 2014 ICES conference, operated continuously on the International Space Station (ISS) for nearly a year. The MGM is designed to measure oxygen, carbon dioxide, ammonia and water vapor in ambient cabin air in a low power, relatively compact device. While on board, the MGM experienced a number of challenges, unplanned and planned, including a test of the ammonia channel using a commercial medical ammonia inhalant. Data from the unit was downlinked once per week and compared with other analytical resources on board, notably the Major Constituent Analyzer (MCA), a magnetic sector mass spectrometer. MGM spent the majority of the time installed in the Nanoracks Frame 2 payload facility in front breathing mode (sampling the ambient environment of the Japanese Experiment Module), but was also used to analyze recirculated rack air. The capability of the MGM to be operated in portable mode (via internal rechargeable lithium ion polymer batteries or by plugging into any Express Rack 28VDC connector) was a part of the usability demonstration. Results to date show unprecedented stability and accuracy of the MGM vs. the MCA for oxygen and carbon dioxide. The ammonia challenge (approx. 75 ppm) was successful as well, showing very rapid response time in both directions. Work on an expansion of capability in a next generation MGM has just begun. Combustion products and hydrazine are being added to the measurable target analytes. An 8 to 10 gas monitor (aka Gas Tricorder 1.0) is envisioned for use on ISS, Orion and Exploration missions.

  2. Children’s health and development: results of a 20-year monitoring

    Directory of Open Access Journals (Sweden)

    Aleksandra Anatol’evna Shabunova

    2014-11-01

    Full Text Available The analysis of the data from domestic and foreign theory and practice has shown that the monitoring of the cohort of children is the most effective method of studying and assessing the health and development of children in order to make efficient and adequate management decisions. The paper presents the results of the medical-and-sociological monitoring “Research into the conditions for the formation of a healthy generation”, performed by RAS Institute of Socio-Economic Development of Territories since 1995 with the active support on the part of the Vologda Oblast Department of Healthcare. The authors have found out that each age period is characterized by a specific set of factors influencing health. Infancy and early age are dominated by the impact of medico-biological and social factors (poor health of the parents; low level of hemoglobin during pregnancy; mother’s smoking during pregnancy; labour conditions of the mother that do not meet sanitary standards; specifics of the infant’s feeding. In preschool and primary school age greater importance is attached to environmental factors, lifestyle and standard of living of the family (comfort of living conditions, environmental conditions in the area of residence, level of sociohygienic literacy and health-preserving activity of the parents. Using the cohort of children born in 2014 as an example, the authors show certain positive trends that emerged during the reforms of the economy and social sphere, reflected in the living conditions of families with children, in the level of satisfaction with their health, infant health, and key indicators of obstetrics system. In this regard, the authors substantiate the necessity of such monitoring to determine the correct vector of government policy

  3. Malaysia's Experience in the Monitoring of Investment and Results of Water Resources Management

    Science.gov (United States)

    Zakaria, Salmah Binti; Lee, Jin

    2010-05-01

    The current status of IWRM implementation in Malaysia, overview of development planning process and financial allocations together with monitoring of IWRM in Malaysia are first presented. This is followed by a case study review of Malaysia's 9th 5-year Development Plan (2005-2010) so as to provide a deeper understanding and appreciation of the current approach adopted by the Malaysian government in the formulation of development policies, project planning, budget allocation and o monitoring of projects. Arising from the review it was highlighted that the water-related, sectoral developmental objectives are found in all the 5 developmental thrusts in the 9th Malaysia Plan. This is because water is an essential natural resource and is also an economic good. Thus, it was concluded that in order for the monitoring of investments in IWRM and results to be effective and useful to support policy formulation to achieve the goal of IWRM there is a need for a collation of all information reported under the different, water-related, sectoral developmental objectives in the 9th Malaysia Plan to be organised within an IWRM framework. It was also concluded that a major IWRM challenge for Malaysia is how to make the transition from the current, narrow, sector-specific, financial and budgeting paradigm of the sectorial agencies to the “total cost” paradigm that involves taking into consideration and integrating the costs in other sectors affected by any projects proposed within a sector. The current, sectorial-focus approach, adopted in the 9th Malaysia Plan, logically measures the effectiveness of sectorial agencies by their ability to achieve their immediate sectorial goals and targets, most often with emphasis on infrastructure projects since the impacts of such projects are usually immediate and visible. However, the use of such approach alone, without taking into account the costs that are borne by other interfacing sectors, and also within the sector over the long term

  4. Twenty years of children’s health monitoring: organization, results, conclusions

    Directory of Open Access Journals (Sweden)

    Aleksandra Anatol’evna Shabunova

    2015-05-01

    Full Text Available Deep understanding of human potential reproduction, presenting it as a continuous cycle and reflecting the continuity of generations, is significant for the formation of health and development of children. Today’s children will determine the future of Russian society. It is they who in 10–15 years will be a major part of the labor and creative population, a demographic base of the country. The research into children’s problems through the prism of socio-economic development helps identify targets of the state many-sided policy. The article presents results of the long-term medical sociological monitoring on the formation of child health carried out by the Institute of Socio-Economic Development of Territories of RAS with the support of the Vologda Oblast Healthcare Department since 1995. The special monitoring study of health dynamics in real time is unique not only for the Vologda Oblast, but for Russia as well. It reveals the transformation of a personality and the dependence of these changes on direct and indirect factors. The work’s feature is that it addresses an extremely important and wide range of issues: whether man was born healthy or not, if he/she is unhealthy, then why and why he/she was born unhealthy; whether his/her health after the birth is improving or deteriorating; if health is changing, what causes the changes. The 15 year observations disclose the dynamics of child health in the conditions of transformation processes taking place in the country. If the official statistics only records certain health trends, the monitoring results allow us to talk about them at a qualitatively new level. They reveal the underlying causes of demographic processes. The conclusion is, on the one hand, obvious and, on the other hand, it can not be neglected: economic stability and orderly development of the social sphere are critical for family well-being and child health. The reverse situation leads to the destruction of the family

  5. Percutaneous Ventricular Restoration Therapy Using the Parachute Device in Chinese Patients with Ischemic Heart Failure: Three-Month Primary End-point Results of PARACHUTE China Study

    Institute of Scientific and Technical Information of China (English)

    Yue-Jin Yang; Yong Huo; Ya-Wei Xu; Jian-An Wang; Ya-Ling Han; Jun-Bo Ge; Rui-Yan Zhang

    2016-01-01

    Background:The primary cause of ischemic heart failure (HF) is myocardial infarction (MI) resulting in left ventricle (LV) wall motion abnormality secondary to ventricular remodeling.A prospective,nonrandomized study conducted in China was designed to assess safety and efficacy of the percutaneous ventricular restoration therapy using Parachute device (CardioKinetix,Inc.,CA,USA) in ischemic HF patients as a result of LV remodeling after anterior wall MI.Methods:Thirty-one patients with New York Heart Association (NYHA) Class Ⅱ,Ⅲ ischemic HF,ejection fraction between 15% and 40%,and dilated akinetic or dyskinetic anterior-apical wall without the need to be revascularized were enrolled from seven sites in China from October to December 2014.The Parachute device was implanted through femoral artery.All patients received low-dose aspirin and anticoagulation with warfarin for at least 12 months postdevice implantation.The primary end-point was the assessment of efficacy as measured by the reduction in LV end-systolic volume index (LVESVI) against baseline LVESVI at 3 months postdevice implantation,determined by the echocardiography and measured by echocardiography core laboratory.Quality of life was assessed using EQ-5D and visual analog scale (VAS).For quantitative data comparison,paired t-test (normality data) and signed-rank test (abnormality data) were used;application of signed-rank test was for the ranked data comparison.Results:A change in LVESVI as measured by echocardiography from the preimplant baseline to 3-month postdevice implantation revealed a statistically significant reduction from 77.5 ± 20.0 ml/m2 to 53.1 ± 17.0 ml/m2 (P < 0.0001).The trial met its primary end-point.Of the 31 patients,the procedural success was 96.8%.Overall,NYHA HF class assessment results showed an improvement of more than halfa class at 3 months (P < 0.001).Quality of life assessed by the VAS value increased 11.5 points (P < 0.01),demonstrating improvement at 3

  6. Monitoring changes in soil carbon resulting from intensive production, a non-traditional agricultural methodology.

    Energy Technology Data Exchange (ETDEWEB)

    Dwyer, Brian P.

    2013-03-01

    New Mexico State University and a group of New Mexico farmers are evaluating an innovative agricultural technique they call Intensive Production (IP). In contrast to conventional agricultural practice, IP uses intercropping, green fallowing, application of soil amendments and soil microbial inocula to sequester carbon as plant biomass, resulting in improved soil quality. Sandia National Laboratories role was to identify a non-invasive, cost effective technology to monitor soil carbon changes. A technological review indicated that Laser Induced Breakdown Spectroscopy (LIBS) best met the farmers objectives. Sandia partnered with Los Alamos National Laboratory (LANL) to analyze farmers test plots using a portable LIBS developed at LANL. Real-time LIBS field sample analysis was conducted and grab samples were collected for laboratory comparison. The field and laboratory results correlated well implying the strong potential for LIBS as an economical field scale analytical tool for analysis of elements such as carbon, nitrogen, and phosphate.

  7. Summary of intensive monitoring for radionuclides in fishery products after Fukushima accident and comparison to the results of long term monitoring program in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Fujimoto, Ken; Morita, Takami; Shigenobu, Yuya; Takagi, Kaori; Miki, Shizuho; Kaeriyama, Hideki; Ambe, Daisuke; Ono, Tsuneo [National Research Institute of Fisheries Science, Fisheries Research Agency, 2-12-4, Fukuura, Kanazawa, Yokohama, Kanagawa 236-8648 (Japan)

    2014-07-01

    Monitoring of artificial radionuclides in fishery products started in late 1950's and has over half a century history in Japan. Fisheries Agency (FA), Fisheries Research Agency (FRA) and prefectural organizations have been conducting the monitoring. The intensive monitoring of radioactive material in fishery products started in the late of March 2011 immediately after the Fukushima Dai-ichi Nuclear Power Plant (FDNPP) accident for the coastal area faced to the Pacific Ocean in the eastern area of Japan and for the offshore area. The purpose of this monitoring is to avoid the distribution of fishery products containing radioactive cesium in concentration over the Japanese standard limit (Cs-134+Cs-137: 100 Bq/kg). Japanese monitoring data are opened to public on the FA's and FRA's web page. In this study, we resume the results of intensive monitoring started in 2011 and show the temporal change of concentration of radioactive cesium in fishery product. In Fukushima Prefecture, the ratio of samples exceeding the Japanese standard limit shows a steadily decreasing trend from 53% at Mar.- Jun. 2011 to below 3% at Jul. - Sep. 2013. In other prefectures, the ratio was 6.5% at Mar.- Jun. 2011 and fell gradually, and it has been below to 1% at Jul. - Sep. 2013. In presentation, we show the results of monitoring conducted in the coastal area and deeper water around Japan from long gamma ray measurements with ashed samples by high purified germanium gamma spectrometry. (authors)

  8. Experimental results on rock resistivity and its applications in monitoring and predicting natural disasters

    Science.gov (United States)

    Zhou, Jianguo; Zhu, Tao; Tang, Baolin

    2017-04-01

    There have been many earthquakes occurring in Chinese Mainland. These earthquakes, especially large earthquakes, often cause immeasurable loss. For instance, the 2008 Wenchuan Ms8.0 earthquake killed 70, 000 people and caused 17, 000 people missing. It is well known that this earthquake was not predicted. Why? Were there no precursors? After analyzing the geo-electrical resistivity recording at Chengdu station which is only about 36 km to the epicenter, we find that resistivity had changed abnormally very significantly along NE direction but no outstanding abnormal changes had been observed along NW direction before the earthquake. Perhaps this non-consistent changes result in that this earthquake was not predicted. However, in another standpoint, can another observation way be found to supplement the current geo-electrical resistivity observation in Chinese Mainland in order to improve the probability of catching the precursor? This motivates us to conduct experiments in lab and field. Apparent resistivity data are acquired along three common-midpoint measuring lines during the fixed-rate uniaxial compression on two sets of dry man-made samples and a Magnetite sample. We construct the relative resistivity change images (RRCIs). Our results indicate that all RRCIs show a trending change with stress: with the increase of stress, the resistivity-decreased region (RDR) in the RRCIs shrinks/expands, while the resistivity-increased region (RIR) expands/shrinks gradually, which is in agreement with the field experimental results of earthquake monitoring (Feng et al., 2001). Our results encourage us to conclude that the trending changes in RRCI with stress could probably become a useful indicator in monitoring and predicting earthquakes, volcanic eruptions and large-scale geologic movements. This work is supported by National Natural Science Foundation of China (NSFC, Grant 41574083).

  9. Results of the MITRA project: Monitoring and intervention for the transportation of dangerous goods

    Energy Technology Data Exchange (ETDEWEB)

    Planas, E. [Centre d' Estudis del Risc Tecnologic (CERTEC), Departament d' Enginyeria Quimica, Universitat Politecnica de Catalunya, Diagonal 647, 08028-Barcelona, Catalonia (Spain)], E-mail: eulalia.planas@upc.edu; Pastor, E. [Centre d' Estudis del Risc Tecnologic (CERTEC), Departament d' Enginyeria Quimica, Universitat Politecnica de Catalunya, Diagonal 647, 08028-Barcelona, Catalonia (Spain); Presutto, F. [M3 Systems, 1 Rue des Oiseaux, 31410 Lavernose (France); Tixier, J. [Ecole des Mines d' Ales, Ales (France)

    2008-04-01

    The objective of the MITRA (monitoring and intervention for the transportation of dangerous goods) project was to prototype a new operational system for monitoring the transportation of dangerous goods in Europe based on regional responsibilities. This concept, based on systems used in air traffic control, aims to provide civil security centres with real-time knowledge of the position and contents of dangerous vehicles circulating in their area of responsibility, and, in the event of a dangerous situation, to issue warnings, alerts and crisis management information, thereby allowing intervention teams to react immediately with maximum safety. The project was funded by the European Commission under the 6th Framework Programme (STREP - specific targeted research project - under the Information Society Technologies priority). It started on 1 September 2004 and ended on 31 October 2006. This paper presents the results of this project and the conclusions derived from the field tests carried out in Germany and in the French/Spanish border region in order to test the proposed operational system.

  10. Geomorphic monitoring of two dam removals in northern Iberian Peninsula: methodology, results and lessons learned

    Science.gov (United States)

    Ibisate, Askoa; Ollero, Alfredo; Ballarín, Daniel; Horacio, Jesús; Mora, Daniel; Mesanza, Amaia; Ferrer-Boix, Carles; Acín, Vanesa; Granado, David; Martín-Vide, Juan Pedro

    2017-04-01

    The methodology and results of two dam removals in two different rivers is presented and compared. One removed all-at-once and the second one in a four-stage removal process. Methodology included topographical measurements of the channel, TLS measurements of river bed and bars and sediment grain size and transport. Morphological channel adjustments occurred mainly shortly after dam removals, but with differences among the one removed instantaneously, that was immediate, whereas that conducted by stages that took longer. Degradational processes were observed upstream of both dams, but also aggradational processes (pool filling) upstream of one of them. Flood events reactivated incision and bank erosion, whereas longitudinal profile recovery, grain-size sorting and upstream erosion took longer, especially in that removed in stages, where one year after is total removal its maximum potential erosion attained just the closest reach to the dam and knickpoint upstream migration was still adapting to the new base level position. Lessons learned helped to improve a third in process dam removal geomorphological monitoring, including an improved sediment transport and bank retreat monitoring.

  11. Monitoring Supergiant Fast X-ray Transients with Swift. Results from the first year

    CERN Document Server

    Romano, P; Cusumano, G; La Parola, V; Vercellone, S; Pagani, C; Ducci, L; Mangano, V; Cummings, J; Krimm, H A; Guidorzi, C; Kennea, J A; Hoversten, E A; Burrows, D N; Gehrels, N

    2009-01-01

    Swift has allowed the possibility to give Supergiant Fast X-ray Transients (SFXTs), the new class of High Mass X-ray Binaries discovered by INTEGRAL, non serendipitous attention throughout all phases of their life. We present our results based on the first year of intense Swift monitoring of four SFXTs, IGR J16479-4514, XTE J1739-302, IGR J17544-2619 and AX J1841.0-0536. We obtain the first assessment of how long each source spends in each state using a systematic monitoring with a sensitive instrument. The duty-cycle of inactivity is 17, 28, 39, 55% (5% uncertainty), for IGR J16479-4514, AX J1841.0-0536, XTE J1739-302, and IGR J17544-2619, respectively, so that true quiescence is a rare state. This demonstrates that these transients accrete matter throughout their life at different rates. AX J1841.0-0536 is the only source which has not undergone a bright outburst during our campaign. Although individual sources behave somewhat differently, common X-ray characteristics of this class are emerging such as outb...

  12. Monitoring the Quality of Medicines: Results from Africa, Asia, and South America

    Science.gov (United States)

    Hajjou, Mustapha; Krech, Laura; Lane-Barlow, Christi; Roth, Lukas; Pribluda, Victor S.; Phanouvong, Souly; El-Hadri, Latifa; Evans, Lawrence; Raymond, Christopher; Yuan, Elaine; Siv, Lang; Vuong, Tuan-Anh; Boateng, Kwasi Poku; Okafor, Regina; Chibwe, Kennedy M.; Lukulay, Patrick H.

    2015-01-01

    Monitoring the quality of medicines plays a crucial role in an integrated medicines quality assurance system. In a publicly available medicines quality database (MQDB), the U.S. Pharmacopeial Convention (USP) reports results of data collected from medicines quality monitoring (MQM) activities spanning the period of 2003–2013 in 17 countries of Africa, Asia, and South America. The MQDB contains information on 15,063 samples collected and tested using Minilab® screening methods and/or pharmacopeial methods. Approximately 71% of the samples reported came from Asia, 23% from Africa, and 6% from South America. The samples collected and tested include mainly antibiotic, antimalarial, and antituberculosis medicines. A total of 848 samples, representing 5.6% of total samples, failed the quality test. The failure proportion per region was 11.5%, 10.4%, and 2.9% for South America, Africa, and Asia, respectively. Eighty-one counterfeit medicines were reported, 86.4% of which were found in Asia and 13.6% in Africa. Additional analysis of the data shows the distribution of poor-quality medicines per region and by therapeutic indication as well as possible trends of counterfeit medicines. PMID:25897073

  13. WFC3/UVIS Dark Calibration: Monitoring Results and Improvements to Dark Reference Files

    Science.gov (United States)

    Bourque, M.; Baggett, S.

    2016-04-01

    The Wide Field Camera 3 (WFC3) UVIS detector possesses an intrinsic signal during exposures, even in the absence of light, known as dark current. A daily monitor program is employed every HST cycle to characterize and measure this current as well as to create calibration files which serve to subtract the dark current from science data. We summarize the results of the daily monitor program for all on-orbit data. We also introduce a new algorithm for generating the dark reference files that provides several improvements to their overall quality. Key features to the new algorithm include correcting the dark frames for Charge Transfer Efficiency (CTE) losses, using an anneal-cycle average value to measure the dark current, and generating reference files on a daily basis. This new algorithm is part of the release of the CALWF3 v3.3 calibration pipeline on February 23, 2016 (also known as "UVIS 2.0"). Improved dark reference files have been regenerated and re-delivered to the Calibration Reference Data System (CRDS) for all on-orbit data. Observers with science data taken prior to the release of CALWF3 v3.3 may request their data through the Mikulski Archive for Space Telescopes (MAST) to obtain the improved products.

  14. Mean corpuscular volume of control red blood cells determines the interpretation of eosin-5'-maleimide (EMA) test result in infants aged less than 6 months.

    Science.gov (United States)

    Ciepiela, Olga; Adamowicz-Salach, Anna; Bystrzycka, Weronika; Łukasik, Jan; Kotuła, Iwona

    2015-08-01

    Eosin-5'-maleimide (EMA) binding test is a flow cytometric test used to detect hereditary spherocytosis (HS). To perform the test sample from patients, 5-6 reference samples of red blood are needed. Our aim was to investigate how the mean corpuscular volume (MCV) of red blood cells influences on the value of fluorescence of bounded EMA dye and how the choice of reference samples affects the test result. EMA test was performed in peripheral blood from 404 individuals, including 31 children suffering from HS. Mean fluorescence channel of EMA-RBCs was measured with Cytomics FC500 flow cytometer. Mean corpuscular volume of RBCs was assessed with LH750 Beckman Coulter. Statistical analysis was performed using Graph Pad Prism. The correlation Spearman coefficient between mean channel of fluorescence of EMA-RBCs and MCV was r = 0.39, p result might be negative. Due to different MCV values of RBCs in infancy and ca. Three months later, EMA test in neonates might be interpreted falsely negative. Samples from children younger than 3 months old had EMA test result 86.1 ± 11.7 %, whereas same samples that analyzed 4.1 ± 2.1 later had results of 75.4 ± 4.5 %, p results; thus, we recommend selection of reference samples with MCV in range of ±2 fL compared to MCV of patient RBC's.

  15. Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow-up results

    Science.gov (United States)

    Giles, Francis J.; Bhalla, Kapil N.; Pinilla-Ibarz, Javier; Larson, Richard A.; Gattermann, Norbert; Ottmann, Oliver G.; Hochhaus, Andreas; Radich, Jerald P.; Saglio, Giuseppe; Hughes, Timothy P.; Martinelli, Giovanni; Kim, Dong-Wook; Shou, Yaping; Gallagher, Neil J.; Blakesley, Rick; Baccarani, Michele; Cortes, Jorge; le Coutre, Philipp D.

    2011-01-01

    Nilotinib is a potent selective inhibitor of the BCR-ABL tyrosine kinase approved for use in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP), and in CML-CP and CML-accelerated phase after imatinib failure. Nilotinib (400 mg twice daily) was approved on the basis of the initial results of this phase 2 open-label study. The primary study endpoint was the proportion of patients achieving major cytogenetic response (CyR). All patients were followed for ≥ 24 months or discontinued early. Of 321 patients, 124 (39%) continue on nilotinib treatment. Overall, 59% of patients achieved major CyR; this was complete CyR (CCyR) in 44%. Of patients achieving CCyR, 56% achieved major molecular response. CyRs were durable, with 84% of patients who achieved CCyR maintaining response at 24 months. The overall survival at 24 months was 87%. Adverse events were mostly mild to moderate, generally transient, and easily managed. This study indicates that nilotinib is effective, with a manageable safety profile, and can provide favorable long-term benefits for patients with CML-CP after imatinib failure. This trial was registered at www.clinicaltrials.gov as #NCT00109707. PMID:21098399

  16. Development of Distributed Research Center for monitoring and projecting regional climatic and environmental changes: first results

    Science.gov (United States)

    Gordov, Evgeny; Shiklomanov, Alexander; Okladinikov, Igor; Prusevich, Alex; Titov, Alexander

    2016-04-01

    Description and first results of the cooperative project "Development of Distributed Research Center for monitoring and projecting of regional climatic and environmental changes" recently started by SCERT IMCES and ESRC UNH are reported. The project is aimed at development of hardware and software platform prototype of Distributed Research Center (DRC) for monitoring and projecting regional climatic and environmental changes over the areas of mutual interest and demonstration the benefits of such collaboration that complements skills and regional knowledge across the northern extratropics. In the framework of the project, innovative approaches of "cloud" processing and analysis of large geospatial datasets will be developed on the technical platforms of two U.S. and Russian leading institutions involved in research of climate change and its consequences. Anticipated results will create a pathway for development and deployment of thematic international virtual research centers focused on interdisciplinary environmental studies by international research teams. DRC under development will comprise best features and functionality of earlier developed by the cooperating teams' information-computational systems RIMS (http://rims.unh.edu) and CLIMATE(http://climate.scert.ru/), which are widely used in Northern Eurasia environment studies. The project includes several major directions of research (Tasks) listed below. 1. Development of architecture and defining major hardware and software components of DRC for monitoring and projecting of regional environmental changes. 2. Development of an information database and computing software suite for distributed processing and analysis of large geospatial data hosted at ESRC and IMCES SB RAS. 3. Development of geoportal, thematic web client and web services providing international research teams with an access to "cloud" computing resources at DRC; two options will be executed: access through a basic graphical web browser and

  17. Enamel matrix derivative in propylene glycol alginate for treatment of infrabony defects with or without systemic doxycycline: 12- and 24-month results.

    Science.gov (United States)

    Eickholz, Peter; Röllke, Lasse; Schacher, Beate; Wohlfeil, Martin; Dannewitz, Bettina; Kaltschmitt, Jens; Krieger, Jörg K; Krigar, Diana M; Reitmeir, Peter; Kim, Ti-Sun

    2014-05-01

    This aim of this study is to compare regenerative therapy of infrabony defects with and without administration of post-surgical systemic doxycycline (DOXY) 12 and 24 months after therapy. In each of 57 patients, one infrabony defect (depth ≥ 4 mm) was treated regeneratively using enamel matrix derivative at two centers (Frankfurt am Main and Heidelberg). By random assignment, patients received either 200 mg DOXY per day or placebo (PLAC) for 7 days after surgery. Twelve and 24 months after surgery, clinical parameters (probing depths [PDs] and vertical clinical attachment level [CAL-V]) and standardized radiographs were obtained. Missing data were managed according to the last observation carried forward. Data of 57 patients (DOXY: 28; PLAC: 29) were analyzed (26 males and 31 females; mean age: 52 ± 10.2 years; 13 smokers). In both groups, significant (P DOXY: 3.7 ± 2.2 mm; PLAC: 3.4 ± 1.7 mm), CAL-V gain (DOXY: 2.7 ± 1.9 mm; PLAC: 3.0 ± 1.9 mm), and bone fill (DOXY: 1.6 ± 2.7 mm; PLAC: 1.8 ± 3.0 mm) were observed 24 months after surgery. However, the differences between both groups failed to be statistically significant (PD: P = 0.574; CAL-V: P = 0.696; bone fill: P = 0.318). Systemic DOXY, 200 mg/day for 7 days, after regenerative therapy of infrabony defects did not result in better PD reduction, CAL-V gain, or radiographic bone fill compared with PLAC 12 and 24 months after surgery, which may be attributable to low power and, thus, random chance.

  18. Effect of Bone Marrow-Derived Mononuclear Cell Treatment, Early or Late After Acute Myocardial Infarction: Twelve Months CMR and Long-Term Clinical Results.

    Science.gov (United States)

    Sürder, Daniel; Manka, Robert; Moccetti, Tiziano; Lo Cicero, Viviana; Emmert, Maximilian Y; Klersy, Catherine; Soncin, Sabrina; Turchetto, Lucia; Radrizzani, Marina; Zuber, Michel; Windecker, Stephan; Moschovitis, Aris; Bühler, Ines; Kozerke, Sebastian; Erne, Paul; Lüscher, Thomas F; Corti, Roberto

    2016-07-22

    Intracoronary delivery of autologous bone marrow-derived mononuclear cells (BM-MNC) may improve remodeling of the left ventricle (LV) after acute myocardial infarction (AMI). To demonstrate long-term efficacy of BM-MNC treatment after AMI. In a multicenter study, we randomized 200 patients with large AMI in a 1:1:1 pattern into an open-labeled control and 2 BM-MNC treatment groups. In the BM-MNC groups, cells were either administered 5 to 7 days (early) or 3 to 4 weeks (late) after AMI. Cardiac magnetic resonance imaging was performed at baseline and after 12 months. The current analysis investigates the change from baseline to 12 months in global LV ejection fraction, LV volumes, scar size, and N-terminal pro-brain natriuretic peptide values comparing the 2 treatment groups with control in a linear regression model. Besides the complete case analysis, multiple imputation analysis was performed to address for missing data. Furthermore, the long-term clinical event rate was computed. The absolute change in LV ejection fraction from baseline to 12 months was -1.9±9.8% for control (mean±SD), -0.9±10.5% for the early treatment group, and -0.7±10.1% for the late treatment group. The difference between the groups was not significant, both for complete case analysis and multiple imputation analysis. A combined clinical end point occurred equally in all the groups. Overall, 1-year mortality was low (2.25%). Among patients with AMI and LV dysfunction, treatment with BM-MNC either 5 to 7 days or 3 to 4 weeks after AMI did not improve LV function at 12 months, compared with control. The results are limited by an important drop out rate. URL: http://www.clinicaltrials.gov. Unique identifier: NCT00355186. © 2016 American Heart Association, Inc.

  19. Analytical Results for Agricultural Soils Samples from a Monitoring Program Near Deer Trail, Colorado (USA)

    Science.gov (United States)

    Crock, J.G.; Smith, D.B.; Yager, T.J.B.

    2009-01-01

    Since late 1993, Metro Wastewater Reclamation District of Denver (Metro District, MWRD), a large wastewater treatment plant in Denver, Colorado, has applied Grade I, Class B biosolids to about 52,000 acres of nonirrigated farmland and rangeland near Deer Trail, Colorado, USA. In cooperation with the Metro District in 1993, the U.S. Geological Survey (USGS) began monitoring groundwater at part of this site. In 1999, the USGS began a more comprehensive monitoring study of the entire site to address stakeholder concerns about the potential chemical effects of biosolids applications to water, soil, and vegetation. This more comprehensive monitoring program has recently been extended through 2010. Monitoring components of the more comprehensive study include biosolids collected at the wastewater treatment plant, soil, crops, dust, alluvial and bedrock groundwater, and stream bed sediment. Soils for this study were defined as the plow zone of the dry land agricultural fields - the top twelve inches of the soil column. This report presents analytical results for the soil samples collected at the Metro District farm land near Deer Trail, Colorado, during three separate sampling events during 1999, 2000, and 2002. Soil samples taken in 1999 were to be a representation of the original baseline of the agricultural soils prior to any biosolids application. The soil samples taken in 2000 represent the soils after one application of biosolids to the middle field at each site and those taken in 2002 represent the soils after two applications. There have been no biosolids applied to any of the four control fields. The next soil sampling is scheduled for the spring of 2010. Priority parameters for biosolids identified by the stakeholders and also regulated by Colorado when used as an agricultural soil amendment include the total concentrations of nine trace elements (arsenic, cadmium, copper, lead, mercury, molybdenum, nickel, selenium, and zinc), plutonium isotopes, and gross

  20. Prevalence and predictors of disability 24-months after injury for hospitalised and non-hospitalised participants: results from a longitudinal cohort study in New Zealand.

    Directory of Open Access Journals (Sweden)

    Sarah Derrett

    Full Text Available INTRODUCTION: Most studies investigating disability outcomes following injury have examined hospitalised patients. It is not known whether variables associated with disability outcomes are similar for injured people who are not hospitalised. AIMS: This paper compares the prevalence of disability 24 months after injury for participants in the Prospective Outcomes of Injury Study who were hospitalised and those non-hospitalised, and also seeks to identify pre-injury and injury-related predictors of disability among hospitalised and non-hospitalised participants. METHODS: Participants, aged 18-64 years, were recruited from an injury claims register managed by New Zealand's no-fault injury compensation insurer after referral by health care professionals. A wide range of pre-injury socio-demographic, health and psychosocial characteristics were collected, as well as injury-related characteristics; outcome is assessed using the WHODAS. Multivariable models estimating relative risks of disability for hospitalised and non-hospitalised participants were developed using Poisson regression methods. RESULTS: Of 2856 participants, analyses were restricted to 2184 (76% participants for whom both pre-injury and 24 month WHODAS data were available. Of these, 25% were hospitalised. In both hospitalised and non-hospitalised groups, 13% experience disability (WHODAS≥10 24 months after injury; higher than pre-injury (5%. Of 28 predictor variables, seven independently placed injured participants in the hospitalised group at increased risk of disability 24 months after injury; eight in the non-hospitalised. Only four predictors (pre-injury disability, two or more pre-injury chronic conditions, pre-injury BMI≥30 and trouble accessing healthcare services were common to both the hospitalised and non-hospitalised groups. There is some evidence to suggest that among the hospitalised group, Māori have higher risk of disability relative to non-Māori. CONCLUSIONS: At

  1. Impact of an electronic monitoring device and behavioral feedback on adherence to multiple sclerosis therapies in youth: results of a randomized trial.

    Science.gov (United States)

    Yeh, E Ann; Grover, Stephanie A; Powell, Victoria E; Alper, Gulay; Banwell, Brenda L; Edwards, Kim; Gorman, Mark; Graves, Jennifer; Lotze, Timothy E; Mah, Jean K; Mednick, Lauren; Ness, Jayne; Obadia, Maya; Slater, Ruth; Waldman, Amy; Waubant, Emmanuelle; Schwartz, Carolyn E

    2017-04-09

    To report the results of a randomized controlled trial using an electronic monitoring device (EM) plus a motivational interviewing (MI) intervention to enhance adherence to disease-modifying therapies (DMT) in pediatric MS. Fifty-two youth with MS (16.03 ± 2.2 years) were randomized to receive either MI (n = 25) (target intervention) or a MS medication video (n = 27) (attention control). Primary endpoint was change in adherence. Secondary outcomes included changes in quality of life, well-being and self-efficacy. Random effects modeling and Cohen's effect size computation evaluated intervention impact. Longitudinal random effect models revealed that the MI group decreased their EM adherence (GroupxTime interaction = -0.19), while increasing frequency of parental DMT reminder (26.01)/administration (11.69). We found decreased EM use in the MI group at 6 months (Cohen's d = -0.61), but increased pharmacy refill adherence (d = 0.23). Parental reminders about medication increased in MI subjects vs controls (d = 0.59 at 3 months; d = 0.70 at 6 months). We found increases in self-reported adherence (d = 0.21) at 3 but not 6 months, fewer barriers to adherence at three (d = -0.58) and six months (d = -0.31), better physical (d = 0.23 at 3 months; d = 0.45 at 6 months), emotional (d = 0.25 at 3 months) and self-efficacy function (d = 0.55 at 3 months; 0.48 at 6 months), but worse well-being, including self-acceptance (d = -0.53 at 6 months) and environmental mastery (d = -0.42 at 3 and 6 months) in intervention as compared to control patients. Participants receiving MI + EM experienced worsening on objective measures of adherence and increased parental involvement, but improved on some self- and parent-reported measures. MI participants reported improvements in quality of life and self-efficacy, but worsened well-being.

  2. An Integrated Architecture for Aircraft Engine Performance Monitoring and Fault Diagnostics: Engine Test Results

    Science.gov (United States)

    Rinehart, Aidan W.; Simon, Donald L.

    2015-01-01

    This paper presents a model-based architecture for performance trend monitoring and gas path fault diagnostics designed for analyzing streaming transient aircraft engine measurement data. The technique analyzes residuals between sensed engine outputs and model predicted outputs for fault detection and isolation purposes. Diagnostic results from the application of the approach to test data acquired from an aircraft turbofan engine are presented. The approach is found to avoid false alarms when presented nominal fault-free data. Additionally, the approach is found to successfully detect and isolate gas path seeded-faults under steady-state operating scenarios although some fault misclassifications are noted during engine transients. Recommendations for follow-on maturation and evaluation of the technique are also presented.

  3. Radioactivity in drinking water: regulations, monitoring results and radiation protection issues

    Directory of Open Access Journals (Sweden)

    Cristina Nuccetelli

    2012-12-01

    Full Text Available INTRODUCTION: Drinking waters usually contain several natural radionuclides: tritium, radon, radium, uranium isotopes, etc. Their concentrations vary widely since they depend on the nature of the aquifer, namely, the prevailing lithology and whether there is air in it or not. AIMS: In this work a broad overview of the radioactivity in drinking water is presented: national and international regulations, for limiting the presence of radioactivity in waters intended for human consumption; results of extensive campaigns for monitoring radioactivity in drinking waters, including mineral bottled waters, carried out throughout the world in recent years; a draft of guidelines for the planning of campaigns to measure radioactivity in drinking water proposed by the Environmental Protection Agency (ARPA of Lombardia.

  4. Testbeam results of the upgraded fast beam condition monitor at CMS

    Energy Technology Data Exchange (ETDEWEB)

    Hempel, Maria; Karacheban, Olena; Lohmann, Wolfgang [BTU, Cottbus (Germany); DESY, Zeuthen (Germany); Afanaciev, Konstantin [NCPHEP, Minsk (Belarus); Burtowy, Piotr; Ryjov, Vladimir; Zagozdzinska, Agnieszka [CERN, Geneva (Switzerland); Henschel, Hans; Lange, Wolfgang; Leonard, Jessica Lynn [DESY, Zeuthen (Germany); Levy, Itamar [Tel Aviv University, Tel Aviv (Israel); Przyborowski, Dominik [AGH-UST, Cracow (Poland); Schuwalow, Sergej; Walsh, Roberval [DESY, Hamburg (Germany)

    2016-07-01

    The Fast Beam Condition Monitor BCM1F at CMS is based on single-crystal diamond sensor with nanosecond time resolution. BCM1F delivered luminosity and machine induced background information to the CMS and LHC control room during the first running period of the LHC. A major upgrade to BCM1F was developed and built during the long shutdown of the LHC in 2014. The increased rate and the 25ns spacing should be handled with sensors subdivided by a double pad metallization and a faster new front-end ASIC. A prototype with these new components was investigated in the testbeam at DESY-II. The results are presented and also verified by Superfish simulations.

  5. GPS Dynamic Monitoring Experiment and Result Analysis of Long-Span Cable-Stayed Bridge

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    For the sake of timely appraising the working condition of the bridge, measuring the dynamic characteristics of the bridge structure is very important and necessary. A GPS dynamic monitoring test was carried out in the Wuhan Baishazhou Bridge, which is one of the longest span cable-stayed bridges having been built in China. This paper introduces the experimental implementing scheme and data processing method. The vibration characteristics of the middle span of cable-stayed bridge are availably obtained by use of the spectral analytic approach. The measuring results are very identical to the theoretical designed values. The research demonstrates that, with GPS receiver of the high sampling rate and suitable data processing method, the vibration characteristics of the bridge structure can be determined with high accuracy.

  6. Intercomparison of in vivo monitoring systems in Europe. Results from Risoe National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Lauridsen, B.; Soegaard-Hansen, J.

    1996-12-01

    This report contains the contribution from Risoe National Laboratory to the European project: `Intercomparison of in Vivo Monitoring Systems in Europe`. The whole-body counter at Risoe and the measurement on a phantom used as an intercalibration object in the project is described. In four case studies, prepared by the project coordinator, intakes of radionuclides and resulting doses are calculated. These calculations are based on informations on the radioactive materials taken into the body, routes of intake and on body contents of radionuclides from simulated single or multiple whole-body measurement. The answer from Risoe National Laboratory to two questionnaires - one on the whole-body counting facility and calibration methods and one on the legal requirements is the country - is listed. (au).

  7. Spectral monitoring of AGNSs: Preliminary results for Ark 564 and Arp 102B

    CERN Document Server

    Shapovalova, A I; Ilic, D; Kovacevic, A; Kovacevic, J; Burenkov, A N; Chavushyan, V H

    2012-01-01

    We present preliminary results of the long term spectral monitoring of two active galactic nuclei with different broad line shapes: Ark 564 and Arp 102B. Ark 564 is a bright nearby narrow line Syfert 1 (NLS1) galaxy with relatively narrow permitted optical emission lines and a high FeII/H${\\beta}$ ratio, while Arp 102B is a nearby broad-line radio galaxy with broad double-peaked Balmer emission lines. The spectra of Ark 564 were observed during 11-year period (1999-2009) and the spectra of Arp 102B in the 12-year period (1998-2009), with SAO 6-m and 1-m telescopes (Russia) and the GHAO 2.1-m telescope (Cananea, Mexico).

  8. Methods used by Elsam for monitoring precision and accuracy of analytical results

    Energy Technology Data Exchange (ETDEWEB)

    Hinnerskov Jensen, J. [Soenderjyllands Hoejspaendingsvaerk, Faelleskemikerne, Aabenraa (Denmark)

    1996-12-01

    Performing round robins at regular intervals is the primary method used by ELsam for monitoring precision and accuracy of analytical results. The firs round robin was started in 1974, and today 5 round robins are running. These are focused on: boiler water and steam, lubricating oils, coal, ion chromatography and dissolved gases in transformer oils. Besides the power plant laboratories in Elsam, the participants are power plant laboratories from the rest of Denmark, industrial and commercial laboratories in Denmark, and finally foreign laboratories. The calculated standard deviations or reproducibilities are compared with acceptable values. These values originate from ISO, ASTM and the like, or from own experiences. Besides providing the laboratories with a tool to check their momentary performance, the round robins are vary suitable for evaluating systematic developments on a long term basis. By splitting up the uncertainty according to methods, sample preparation/analysis, etc., knowledge can be extracted from the round robins for use in many other situations. (au)

  9. Monthly errors

    Data.gov (United States)

    U.S. Environmental Protection Agency — The 2006 monthly average statistical metrics for 2m Q (g kg-1) domain-wide for the base and MODIS WRF simulations against MADIS observations. This dataset is...

  10. Swelling Soils and Vegetation Interactions: New Results from PSI Monitoring on Eastern Paris Area (France)

    Science.gov (United States)

    Kaveh, H. F.; Deffontaines, B.; Fruneau, B.; Cojean, R.; Arnaud, A.; Duro, J.

    2010-12-01

    Swelling soils phenomena induce small surface displacements under various climatic conditions that may locally affect suburban individual buildings. The aim of this work, funded by MAIF foundation (Insurance company), is to monitor those small seasonal-dependant displacements through persistent scatterer interferometric (PSI) method. The chosen test site correspond to the eastern Paris basin where "Argiles Vertes de Romainville" Oligocene in age is outcropping and are particularly sensible to swelling soils phenomena well observed during for instance the last major dryness event of the summer 2003. Our major results with Persistent Scatterer Interferometry (PSI) in order to monitor this phenomenon reveal precisely continuous small surface pluricentimetric displacements through time. Furthermore it appears that vegetation more specifically trees, plays a major role for the vertical displacement which is due to the evapotranspiration processes. We therefore precisely map the location and height of the different trees species in the studied area that gave us their potential planimetric roots influence then compare them to the different surrounding buildings using a Geographical Information System (GIS). We then compare our results to both building deformations observed in the fields and the calculated displacements deduced from numerous PSI profiles where an excellent correlation is then observed associated with more than 90% confidence. Even if we still have some uncertainties due for instance to the location of the PSI natural reflectors (+/- 2,5m), we now need in perspective terms to instrument precisely test sites in order to calibrate then validate the PSI displacements and the observed buildings deformations. This new application of PSI interferometry presents high potential to better understand swelling soils processes and associated natural hazards.

  11. Wind turbine wake tracking and its correlations with wind turbine monitoring sensors. Preliminary results

    Science.gov (United States)

    Aubrun, S.; Torres Garcia, E.; Boquet, M.; Coupiac, O.; Girard, N.

    2016-09-01

    Within the frame of the French project ANR SMARTEOLE, a 6-month measurement campaign has been set-up in the north of France to study the wake behaviour of two wind turbines, with an original set-up using: one ground based scanning LIght Detection And Ranging system (LIDAR), 2 nacelle-mounted LIDARs and a nacelle-embedded 2-axis inclinometer. The present paper will give first insight into the results and describe the different post-processing strategies used to prepare the data to be cross-correlated; within the project the final objective is to characterise the influence of the large-scale atmospheric turbulent eddies on the overall wind turbine nacelle displacement and wind turbine wake behaviour.

  12. Long-term monitoring of sleep apnea at home in heart failure patients: preliminary results from the HHH study.

    Science.gov (United States)

    Pinna, G D; Maestri, R; Gobbi, E; Capomolla, S; Campana, C; Emdin, M; Di Lenarda, A; La Rovere, M T; Andrews, D; Johnson, P; Mortara, A; Sleight, P

    2004-01-01

    Sleep apnea is very common in patients with chronic heart failure (CHF) and has important implications in terms of morbidity, mortality and clinical management. Home respiratory telemonitoring might constitute a potential low-cost, widely-applicable alternative to traditional polysomnography in the evaluation and long-term monitoring of breathing disorders in these patients. In this paper we briefly describe the technological infrastructure and present preliminary results of the European Community multicountry trial HHH (Home or Hospital in Heart Failure), which is currently testing a novel system for home telemonitoring of cardiorespiratory signals in CHF patients. The recording and transmitting devices are suitable to be self-managed by the patient. We give a detailed report on the prevalence of nocturnal respiratory disorders at the beginning of the one-year follow-up and on their persistency over the following recordings (one per month). These preliminary findings clearly indicate that intermittent home telemonitoring of respiratory signals based on patient's self-management is feasible in CHF patients and the compliance is high. Reported statistics unambiguously confirm the high prevalence of nocturnal breathing disorders in these patients and clearly show that this phenomenon tends to persist over time.

  13. Chemical, mechanical and sensory monitoring of hot air- and infrared-roasted hazelnuts (Corylus avellana L.) during nine months of storage.

    Science.gov (United States)

    Belviso, Simona; Dal Bello, Barbara; Giacosa, Simone; Bertolino, Marta; Ghirardello, Daniela; Giordano, Manuela; Rolle, Luca; Gerbi, Vincenzo; Zeppa, Giuseppe

    2017-02-15

    Roasted hazelnuts can be consumed as whole nuts, or as an ingredient in the confectionary and bakery industries and are highly appreciated for their typical taste, aroma and crunchy texture. In this work, two hazelnut types (TGT, Ordu) from two harvests were roasted using two different systems (hot air, infrared) at different time/temperature combinations, and the evolution of oxidative stability, the total phenolic content (TPC), the antioxidant capacity, the mechanical and acoustic properties and the sensory perception were determined during storage. The results showed that the oxidative stability was increased by roasting hazelnuts at 120°C for 40min with hot air system. Similar overall trends were not found for the TPC, the antioxidant capacity and the mechanical-acoustic properties. However, for the maintenance of high antioxidant activity, a storage time of 6months at 4°C is recommended. The two roasting systems gave hazelnuts with significant sensory differences only at high roasting temperature.

  14. Earth Observation in Support of Sustainable Urban Planning: Results of the Dragon-3 Monitor Project

    Science.gov (United States)

    Cartalis, C.; Polydoros, A.; Mavrakou, T.; Asimakopoulos, D. N.

    2016-08-01

    Sustainable urban planning increasingly demands innovative concepts and techniques to obtain up-to-date and area-wide information on the characteristics and development of the urban system. In this paper, a thorough and conclusive presentation is made in terms of the results of the DRAGON-3 MONITOR project as based on the use of Earth Observation. Results refer in particular to a set of EO based dynamic urban indicators (i.e. urban form and expansion, land use/land cover changes, land surface temperature distribution, the presence and strength of urban heat island) with the capacity to describe the state, dynamic changes and interaction of the land and thermal environment in urban areas. Furthermore results are assessed in terms of their potential to operationally support sustainable urban planning and bridge the gap between EO scientists and urban planners. Constraints related to the spatial resolution and revisit time of satellite sensors are discussed as they influence the accuracy and applicability of the indicators. Methodologies to improve the applicability of the indicators are also discussed along with the presentation of the respective results.

  15. Foliar nutrients in Italian forests: results from the 1995-2009 monitoring network sites CONECOFOR

    Directory of Open Access Journals (Sweden)

    De Cinti B

    2013-11-01

    Full Text Available Foliar nutrients in Italian forests: results from the 1995-2009 monitoring network sites CONECOFOR. In 1995, the Italian Forest Service (CFS established the National Network for Forest Ecosystem Monitoring (CONECOFOR with the aim to study the ecological interactions among structural and functional components of forest stands. In the 31 permanent plots of the CONECOFOR Network, surveys are carried out including vegetation, trees crown condition, chemistry of leaves and soils, tree growth, atmospheric deposition, climate, microclimate, ozone and biodiversity. These surveys are carried out by CFS in collaboration with several scientific institutions. In such context, IBAF/CNR is specifically involved in the investigation of foliage chemical content. The foliar nutritional status was analyzed in 25 sites, taking as a reference the values published by the ICP-Forests and those published in the literature. The study involved 7 forest species (Quercus cerris, Q. petraea, Q. robur, Q. ilex, Fagus sylvatica, Carpinus betulus and Picea abies investigating the concentrations of the major macronutrients as nitrogen (N, phosphorus (P, potassium (K, magnesium (Mg, sulfur (S and calcium (Ca and the N/P ratio. In beech, N, S and K were found in quite high concentrations, though without showing imbalances due to concentration excesses. Ca and Mg are present in very high concentrations, highlighting the possibility of imbalances, especially in relation to the other nutrients. For these two nutrients, spruce shows substantially balanced conditions as also for N/P ratio. For deciduous Oaks nutrients arewithin the parameters of normality, with the exception of Ca. This has been observed in 4 out of the 6 studied sites, with potential indication of nutritional imbalances related to Calcium. Nutrient concentrations in Holm oak are within the average of published data, except for Ca and Mg of site TOS-1, the former being slightly low, the latter being unusually high

  16. Performance of low-cost GNSS receiver for landslides monitoring: test and results

    Directory of Open Access Journals (Sweden)

    Alberto Cina

    2015-07-01

    Full Text Available Italy is deeply afflicted by geo-hydrological risk, where a predominant part of its area is under risk.Recently, advanced research and sensors have played an important role in realizing automatic systems for landslide monitoring and to alerting. The cost of these systems, considering all parts, limits their use and the cost of each sensor influences the investment. Geodetic global navigation satellite system (GNSS receivers, which are commonly used to realize these activities, are an appropriate example; however, their costs are quite high.The aim of this research was to test the actual performance of a mass-market GNSS receiver, with the purpose of verifying if such type of sensors can be used for landslide monitoring. In particular, the benefits due to the coupling between mass-market receivers and products offered by a network of GNSS permanent stations (e.g. Virtual RINEX have been investigated.To verify the capability of these sensors to detect a deformation, under the minimum deformation detectable point of view, a special slide was built, in order to conduct a dedicated test. The support was moved both in horizontal and vertical directions with high precision, with purpose to detect correctly a three-dimensional movement.Tests were carried out considering the dependence of some factors: the most important are the acquisition time and the distance from the GNSS reference station. Interesting is the use of virtual reference station based on GNSS network, as a reference station: the performance achieved using Virtual RINEX for the control of movements and deformations are analysed. The accuracy and precision of movement determination were evaluated and compared, for each test, considering the different factors. The tests and results are described in this contribution.

  17. Results of ambulatory arterial blood pressure monitoring in children with obesity

    Directory of Open Access Journals (Sweden)

    Faruk Öktem

    2010-12-01

    Full Text Available Objectives: The relationship between obesity and essential hypertension is well known. In this study, we aimed to evaluate ambulatory arterial blood pressure monitoring of obese and non-obese children who had similar demographic characteristics.Materials and methods: Seventy one children and adolescents (n=39 obesity, n=32 controls were studied. Blood pressure of the children were measured by 24 hour ambulatory blood pressure monitoring device.Results: Obese children had significantly higher mean blood pressure values (systolic 121.9±11.7 mmHg, diastolic 70.2±5.3 mmHg than control subjects (systolic 109.3±6.7 mmHg, diastolic 65.1±4.6 mmHg, p0.05. Blood pressure load was found to be increased in obese children compared to the controls (%13.6±12.9 and %2.6±3.4, respectively; p<0.05. Serum total cholesterol and LDL-cholesterol levels of obese children (181.1±33.4 and 131.1±23.1mg/dl were significantly higher than those of the controls (134.3±11.1 and 103.3±14.2 mg/dl, p<0.05.Conclusions: Obesity in children and adolescents should not be regarded as variations of normality, but as abnormality with an extremely high risk for the development of hypertension and hyperlipidemia in adulthood.

  18. A network of autonomous surface ozone monitors in Antarctica: technical description and first results

    Directory of Open Access Journals (Sweden)

    S. J.-B. Bauguitte

    2011-04-01

    Full Text Available A suite of 10 autonomous ozone monitoring units, each powered using renewable energy, was developed and built to study surface ozone in Antarctica during the International Polar Year (2007–2009. The monitoring systems were deployed in a network around the Weddell Sea sector of coastal Antarctica with a transect up onto the Antarctic Plateau. The aim was to measure for a full year, thus gaining a much-improved broader view of boundary layer ozone seasonality at different locations as well as of factors affecting the budget of surface ozone in Antarctica. Ozone mixing ratios were measured based on UV photometry using a modified version of the commercial 2B Technologies Inc. Model 202 instrument. All but one of the autonomous units measured successfully within its predefined duty cycle throughout the year, with some differences in performance dependent on power availability and ambient temperature. Mean data recovery after removal of outliers was on average 70% (range 44–83% and precision varied between 1.5 and 8 ppbv, thus was sufficiently good to resolve year-round the main ozone features of scientific interest. We conclude that, with adequate power, and noting a minor communication problem, our units would be able to operate successfully at ambient temperatures down to −60 °C. Systems such as the one described in this paper, or derivatives of it, could therefore be deployed either as local or regional networks elsewhere in the Arctic or Antarctic. Here we present technical information and first results from the experiment.

  19. First results of an integrated monitoring concept to detect brine migration processes in freshwater aquifers

    Science.gov (United States)

    Möller, M.; Schmidt-Hattenberger, C.; Wagner, F.; Schröder, S.

    2012-04-01

    The reduction of new carbon dioxide emissions is an important contribution to realise climate change mitigation solutions. One possibility consists in the long-term storage of industrial produced greenhouse gas in deep saline aquifers. The most important research focus of the multidisciplinary integrated project BRINE is to ensure the safe storage operation. This research work refers to an area in eastern Brandenburg (Germany). However, the analysis can be applied to regions with comparable geological characteristics. The relevant reservoir horizon is located within a classic anticlinal structure, generated by salt tectonic processes. Due to the local geological site specifics, the CO2 injection could cause a pressure build-up and thus a brine migration in the reservoir layer. For this reason, an adequate monitoring system for the observation of possible brine displacement into upper freshwater aquifers is essential. For both the qualitatively and quantitatively investigation a combination of several geophysical methods is needed. The electrical resistivity tomography (ERT) is a measurement method with a comparatively high spatial resolution on small scales. Therefore it will be generally used for borehole and near subsurface investigations. The presented monitoring concept focusses on three potential pathways. Beside regional fault-zones, also formation defects in the upper aquitards and leakages around the wellbore could promote a saltwater migration. The main objective is to find an optimal combination of several electrode arrays like surface, surface-downhole and cross-borehole configurations to detect time-lapse effects of the resistivity distribution in the subsurface. By means of numerical modelling studies of different salinisation scenarios, we have tested several standard and several adapted electrode arrays. In order to further improve the results, an inversion code based on the measured resistance ratios is used. Parallel to the large-scale modelling

  20. Factors Associated with Anemia among Children Aged 6–23 Months Attending Growth Monitoring at Tsitsika Health Center, Wag-Himra Zone, Northeast Ethiopia

    Directory of Open Access Journals (Sweden)

    Haile Woldie

    2015-01-01

    Full Text Available Background. Globally, about 47.4% of children under five are suffering from anemia. In Ethiopia, 60.9% of children under two years are suffering from anemia. Anemia during infancy and young childhood period is associated with poor health and impaired cognitive development, leading to reduced academic achievement and earnings potential in their adulthood life. However, there is scarcity of information showing the magnitude of iron deficiency anemia among young children in Ethiopia. Therefore, this study aimed at assessing prevalence and associated factors of iron deficiency anemia among children under two (6–23 months. Methods. Institution based cross-sectional study was carried out from March to May, 2014, at Tsitsika Health Center in Wag-Himra Zone, Northeast Ethiopia. Systematic random sampling technique was employed. Automated hemoglobin machine was used to determine the hemoglobin level. Socioeconomic and demographic data were collected by using a pretested and structured questionnaire. Binary logistic regression analysis was used to identify associated factors and odds ratio with 95% CI was computed to assess the strength of association. Results. Total of 347 children participated in this study. The overall prevalence of anemia was 66.6%. In multivariate logistic regression analysis, male sex (AOR = 3.1 (95% CI: 1.60–5.81, 9–11 months of age (AOR = 9.6 (95% CI: 3.61–25.47, poor dietary diversity (AOR = 3.2 (95% CI: 1.35–7.38, stunting (AOR = 2.7 (95% CI: 1.20–6.05, diarrhea (AOR = 4.9 (1.63–14.59, no formal education (AOR = 2.6 (95% CI: 1.26–5.27, early initiation of complementary food (AOR = 11.1 (95% CI: 4.08–30.31, and lowest wealth quintile (AOR = 3.0 (95% CI: 1.01–8.88 were significantly associated with anemia. Conclusion. The overall prevalence of anemia among children who aged 6–23 months has sever public health importance in the study area. Integrated efforts need to be prioritized to improve health as well as

  1. Factors Associated with Anemia among Children Aged 6–23 Months Attending Growth Monitoring at Tsitsika Health Center, Wag-Himra Zone, Northeast Ethiopia

    Science.gov (United States)

    Woldie, Haile; Kebede, Yigzaw; Tariku, Amare

    2015-01-01

    Background. Globally, about 47.4% of children under five are suffering from anemia. In Ethiopia, 60.9% of children under two years are suffering from anemia. Anemia during infancy and young childhood period is associated with poor health and impaired cognitive development, leading to reduced academic achievement and earnings potential in their adulthood life. However, there is scarcity of information showing the magnitude of iron deficiency anemia among young children in Ethiopia. Therefore, this study aimed at assessing prevalence and associated factors of iron deficiency anemia among children under two (6–23 months). Methods. Institution based cross-sectional study was carried out from March to May, 2014, at Tsitsika Health Center in Wag-Himra Zone, Northeast Ethiopia. Systematic random sampling technique was employed. Automated hemoglobin machine was used to determine the hemoglobin level. Socioeconomic and demographic data were collected by using a pretested and structured questionnaire. Binary logistic regression analysis was used to identify associated factors and odds ratio with 95% CI was computed to assess the strength of association. Results. Total of 347 children participated in this study. The overall prevalence of anemia was 66.6%. In multivariate logistic regression analysis, male sex (AOR = 3.1 (95% CI: 1.60–5.81)), 9–11 months of age (AOR = 9.6 (95% CI: 3.61–25.47)), poor dietary diversity (AOR = 3.2 (95% CI: 1.35–7.38)), stunting (AOR = 2.7 (95% CI: 1.20–6.05)), diarrhea (AOR = 4.9 (1.63–14.59)), no formal education (AOR = 2.6 (95% CI: 1.26–5.27)), early initiation of complementary food (AOR = 11.1 (95% CI: 4.08–30.31)), and lowest wealth quintile (AOR = 3.0 (95% CI: 1.01–8.88)) were significantly associated with anemia. Conclusion. The overall prevalence of anemia among children who aged 6–23 months has sever public health importance in the study area. Integrated efforts need to be prioritized to improve health as well as

  2. Factors Associated with Anemia among Children Aged 6-23 Months Attending Growth Monitoring at Tsitsika Health Center, Wag-Himra Zone, Northeast Ethiopia.

    Science.gov (United States)

    Woldie, Haile; Kebede, Yigzaw; Tariku, Amare

    2015-01-01

    Background. Globally, about 47.4% of children under five are suffering from anemia. In Ethiopia, 60.9% of children under two years are suffering from anemia. Anemia during infancy and young childhood period is associated with poor health and impaired cognitive development, leading to reduced academic achievement and earnings potential in their adulthood life. However, there is scarcity of information showing the magnitude of iron deficiency anemia among young children in Ethiopia. Therefore, this study aimed at assessing prevalence and associated factors of iron deficiency anemia among children under two (6-23 months). Methods. Institution based cross-sectional study was carried out from March to May, 2014, at Tsitsika Health Center in Wag-Himra Zone, Northeast Ethiopia. Systematic random sampling technique was employed. Automated hemoglobin machine was used to determine the hemoglobin level. Socioeconomic and demographic data were collected by using a pretested and structured questionnaire. Binary logistic regression analysis was used to identify associated factors and odds ratio with 95% CI was computed to assess the strength of association. Results. Total of 347 children participated in this study. The overall prevalence of anemia was 66.6%. In multivariate logistic regression analysis, male sex (AOR = 3.1 (95% CI: 1.60-5.81)), 9-11 months of age (AOR = 9.6 (95% CI: 3.61-25.47)), poor dietary diversity (AOR = 3.2 (95% CI: 1.35-7.38)), stunting (AOR = 2.7 (95% CI: 1.20-6.05)), diarrhea (AOR = 4.9 (1.63-14.59)), no formal education (AOR = 2.6 (95% CI: 1.26-5.27)), early initiation of complementary food (AOR = 11.1 (95% CI: 4.08-30.31)), and lowest wealth quintile (AOR = 3.0 (95% CI: 1.01-8.88)) were significantly associated with anemia. Conclusion. The overall prevalence of anemia among children who aged 6-23 months has sever public health importance in the study area. Integrated efforts need to be prioritized to improve health as well as appropriate infant and

  3. Preliminary results of continuous GPS monitoring of surface deformation at the Aquistore underground CO2 storage site

    Science.gov (United States)

    Craymer, M. R.; Henton, J. A.; Piraszewski, M.; Silliker, J.; Samsonov, S. V.

    2013-12-01

    Aquistore is a demonstration project for the underground storage of CO2 at a depth of ~3350 m near Estevan, Saskatchewan, Canada. An objective of the project is to design, adapt, and test non-seismic monitoring methods that have not been systematically utilized to date for monitoring CO2 storage projects, and to integrate the data from these various monitoring tools to obtain quantitative estimates of the change in subsurface fluid distributions, pressure changes and associated surface deformation. Monitoring methods being applied include satellite-, surface- and wellbore-based monitoring systems and comprise natural- and controlled-source electromagnetic methods, gravity monitoring, GPS, synthetic aperture radar interferometry (InSAR), tiltmeter array analysis, and chemical tracer studies. Here we focus on the GPS monitoring of surface deformation. Five of the planned thirteen GPS monitoring stations were installed in November 2012 and results subsequently processed on a weekly basis. The first GPS results prior to CO2 injection have just been determined using both precise point positioning (PPP) and baseline processing with the Bernese GPS Software. The time series of the five sites are examined, compared and analysed with respect to monument stability, seasonal signals and estimates of expected regional ground motion. The individual weekly network solutions are combined together in a cumulative 4D network solution to provide a preliminary local velocity field in the immediately vicinity of the injection well. The results are compared to those from InSAR.

  4. Clinical usefulness and patient satisfaction with a musculoskeletal ultrasound clinic: results of a 6-month pilot service in a Rheumatology Unit.

    Science.gov (United States)

    Acebes, Carlos; Harvie, John P; Wilson, Alison; Duthie, Janet; Bowen, Fran; Steven, Malcolm

    2016-12-01

    There is no agreement among the rheumatology community in how to implement the musculoskeletal ultrasound (MSUS) technique in the Rheumatology Divisions. To test the perceived usefulness of the MSUS, under consensus indications, for referring colleagues for the clinical management of their patients with inflammatory arthritis (IA) and to score the satisfaction level of the patients with different aspects of the ultrasound (US) examination, after attend to the MSUS clinic. A written questionnaire-based survey regarding the usefulness and satisfaction with the implementation of a pilot MSUS clinic in a Rheumatology Unit. Over a 6-month period, 43 patients attended 10 MSUS clinics. Referral agreed indications were: US assisting in early/subclinical diagnosis (35 %), decision making with patient treatment (44 %), monitoring of disease activity/treatment response (39 %) and US-guided injection (11 %). Average scores of the referrers regarding usefulness of the information provided for the US for these indications were 8.0, 8.3, 8.7 and 8.6, respectively, with a high score of 9.0 regarding the valuable support of the US for the management of their patients with IA. Patient satisfaction scores in responders (44 %) were averaged 9.5 and higher for receiving an adequate explanation of the US procedure, indications, US findings and their significance, lack of discomfort and length of the appointment. The average score was slightly lower (8.5) for the waiting time frame for the appointment for the MSUS examination. The referrers expressed a perception of usefulness of our pilot US clinic, under previous consensus indications, for the clinical management of their patients with IA. In addition, this MSUS clinic seemed to show a good acceptability and a high satisfaction scores for the patients.

  5. Effectiveness of an educational intervention to improve child feeding practices and growth in rural China: updated results at 18 months of age.

    Science.gov (United States)

    Zhang, Jingxu; Shi, Ling; Chen, Da-Fang; Wang, Jing; Wang, Yan

    2013-01-01

    Inappropriate complementary feeding practices have led to, in part, significant disparities in growth and nutritional status between rural and urban children in China. A cluster-randomised, controlled trial was implemented in Laishui, China to assess the effectiveness of an educational intervention on caregivers' feeding practices and children's growth. Eight townships were randomly assigned to the intervention or control. Five hundred ninety-nine healthy infants were enrolled at 2-4 months old, and were followed up at ages 6, 9, 12, 15 and 18 months. The intervention group received information on enhanced home-prepared recipes and food preparation and hygiene through group training, counselling and home visit. Key outcomes were children's physical growth, caregivers' knowledge and behaviours on complementary feeding, and the infant and child feeding index (ICFI). Analysis was by intention to treat. The intervention group achieved better knowledge and practices related to complementary feeding, and significantly higher ICFI scores at each follow-up point. Children in the intervention group achieved higher z-scores for weight-for-age (WAZ) and weight-for-height (WHZ) than the control (0.18 vs. 0.01 and 0.49 vs. 0.19, respectively) at 18 months old, and were less likely to have stunted growth (odds ratio = 0.71, 95% confidence interval: 0.53-0.94). Mixed model showed that the intervention group achieved significantly better linear growth over time, including WAZ (P = 0.016), WHZ (P = 0.030) and HAZ (P = 0.078). These results indicated that an educational intervention delivered through local health services can enhance caregivers' knowledge and practices of complementary feeding and ultimately improve children's growth.

  6. Treatment retention, drug use and social functioning outcomes in those receiving 3 months versus 1 month of supervised opioid maintenance treatment. Results from the Super C randomized controlled trial.

    Science.gov (United States)

    Holland, Richard; Maskrey, Vivienne; Swift, Louise; Notley, Caitlin; Robinson, Angela; Nagar, Jess; Gale, Tim; Kouimtsidis, Christos

    2014-04-01

    Supervised consumption of opioid maintenance treatment (OMT) is standard in many drug centres reducing drug diversion, but is costly. We aimed to determine whether supervised consumption of OMT improved retention and other measures of drug use. Pragmatic randomized controlled trial comparing 3 months of daily supervised consumption of OMT with 1 month or less of daily supervised OMT, then daily unsupervised consumption. Four community drug services in the United Kingdom. A total of 293 opioid-dependent patients entering OMT. retention in treatment at 12 weeks. Secondary: retention at 6 months; illicit drug use [Maudsley Addiction Profile (MAP)]; quality of life (SF-12 and MAP); criminality (MAP); and social functioning. No significant between-group difference was observed for the primary outcome: 69% (100 of 145) supervised and 74% (109 of 148) unsupervised were retained [odds ratio (OR) = 0.74, 95% confidence interval (CI) = 0.43-1.27]. Per protocol survival analysis suggested that supervised patients were less well retained (hazard ratio for retention = 0.71, 95% CI = 0.51-1.00). Illicit opioid use reduced in both groups and, while not statistically significant by intention-to-treat analysis, favoured unsupervised patients in per protocol analysis (odds of positive opioid screen for supervised versus unsupervised = 2.07, 95% CI = 1.05-4.06). Data on criminal activity also favoured unsupervised patients with 21% supervised patients committing crime versus 9% unsupervised (OR = 3.37, 95% CI = 1.28-8.86). There was no evidence of a difference in treatment retention or opioid use rates between patients whose consumption of opioid maintenance treatment was supervised for 3 months daily (except Saturdays) compared with supervision for 1 month. There was some evidence that longer periods of supervised consumption were associated with higher levels of criminality. © 2013 Society for the Study of Addiction.

  7. Monitor Sustainable Procurement 2010. Results of a monitoring survey for sustainable procurement in 2010; Monitor Duurzaam Inkopen 2010. Resultaten monitoringonderzoek duurzaam inkopen 2010

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-06-15

    Every two years, the Dutch Ministry of Infrastructure and the Environment measures the progress in realizing the targets for sustainable procurement. The first Monitor Sustainable Procurement was conducted for 2010. Next to measuring the percentage of sustainable procurement, research was also conducted on how and in what manner sustainable procurement is embedded in government organizations and how it functions in practice. [Dutch] Het ministerie van Infrastructuur en Milieu meet elke twee jaar de voortgang van het bereiken van de doelstellingen voor duurzaam inkopen. Over 2010 is een eerste uitgebreide Monitor Duurzaam Inkopen uitgevoerd. Naast de meting van het percentage duurzaam inkopen is ook onderzocht hoe en op welke manier duurzaam inkopen verankerd is binnen overheidsorganisaties en in de praktijk functioneert.

  8. Comparison of 12-month anatomic and functional results between Z6 femtosecond laser-assisted and manual trephination in deep anterior lamellar keratoplasty for advanced keratoconus.

    Science.gov (United States)

    Blériot, A; Martin, E; Lebranchu, P; Zimmerman, K; Libeau, L; Weber, M; Vabres, B; Orignac, I

    2017-06-01

    The management of severe keratoconus requires corneal transplantation, for which the gold standard is deep anterior lamellar keratoplasty (DALK), preserving the healthy Descemet's membrane and endothelium. The safety and reproducibility of corneal cuts have been improved by the evolution of femtosecond lasers in refractive surgery, and femtosecond laser in DALK would seem to provide the same advantages over the manual method. In our retrospective study, we compare functional and anatomical results of femtosecond-assisted DALK versus manual trephination DALK in patients with keratoconus in stage 4 of the Krumeich classification. It is a retrospective study including all patients with stage 4 keratoconus who underwent femtosecond laser-assisted DALK between November 2012 and November 2015 in Nantes university medical center. We compared those patients to a group of patients who underwent manual DALK in the same period, paired by age and maximal keratometry. We assessed visual acuity, pachymetry, endothelial cell density (specular microscopy), and keratometry before surgery and at 4, 8 and 12 months of follow-up. Laser settings and intraoperative complications were recorded. Nineteen patients underwent surgery by femtosecond-assisted DALK, 6 women and 12 men with average age 30.2±10.8 years at transplantation. They were paired with a group of 17 patients who underwent manual DALK in order to compare results. Before surgery, mean visual acuity in the femtosecond group was 0.90 logMAR versus 0.89 logMAR in the manual group, showing no statistically significant difference (P=0.96). Both groups were similar in terms of preoperative age, mean keratometry, pachymetry and endothelial cell density. Average visual acuity post-surgery was 0.27; 0.26; and 0.14 logMAR for femtosecond DALK versus 0.27; 0.17 et 0.25 for manual DALK at 4, 8 and 12 months follow-up respectively, showing no statistically significant difference. After surgery, at 4, 8 and 12 months, mean

  9. Prototype Repository. Acoustic emission and ultrasonic monitoring results from deposition hole DA3545G01 in the Prototype. Repository between April 2007 and September 2007

    Energy Technology Data Exchange (ETDEWEB)

    Zolezzi, F.; Haycox, J.R.; Pettitt, W.S. (Applied Seismology Consultants, Shrewsbury (United Kingdom))

    2008-07-01

    This six-month period of ultrasonic monitoring in the Prototype Repository Experiment, has been undertaken with the following objectives; - Produce accurate source locations for AEs so as to delineate the spatial and temporal extent of any brittle microcracking within the rock mass around the deposition hole and locate any movements on pre-existing macroscopic fractures; - Conduct regular ultrasonic surveys to assess the effect of heating and other environmental changes on the velocity and amplitude of transmitted ultrasonic waves; - Investigate changes in dynamic moduli and crack density to show how the properties of the rock volume around the deposition hole change through the experiment; - Relate the AE and ultrasonic measurements to the measured in situ stress regime and other operating parameters such as temperature and fluid pressure; - Outline how the results from this reporting period relate to previous monitoring periods, and into the overall experimental aims and objectives.

  10. Prototype Repository. Acoustic emission and ultrasonic monitoring results from deposition hole DA3545G01 in the Prototype. Repository between April 2007 and September 2007

    Energy Technology Data Exchange (ETDEWEB)

    Zolezzi, F.; Haycox, J.R.; Pettitt, W.S. (Applied Seismology Consultants, Shrewsbury (United Kingdom))

    2008-07-01

    This six-month period of ultrasonic monitoring in the Prototype Repository Experiment, has been undertaken with the following objectives; - Produce accurate source locations for AEs so as to delineate the spatial and temporal extent of any brittle microcracking within the rock mass around the deposition hole and locate any movements on pre-existing macroscopic fractures; - Conduct regular ultrasonic surveys to assess the effect of heating and other environmental changes on the velocity and amplitude of transmitted ultrasonic waves; - Investigate changes in dynamic moduli and crack density to show how the properties of the rock volume around the deposition hole change through the experiment; - Relate the AE and ultrasonic measurements to the measured in situ stress regime and other operating parameters such as temperature and fluid pressure; - Outline how the results from this reporting period relate to previous monitoring periods, and into the overall experimental aims and objectives.

  11. MONITORING OF COAL BED EXTRACTION AS AN EFFECTIVE TOOL FOR IMPROVING THE PRODUCTION RESULTS OF A MINE

    Directory of Open Access Journals (Sweden)

    Witold BIAŁY

    2015-07-01

    Full Text Available The basic source of information necessary for proper and effective management of a hard coal mine is continuous monitoring of the mining process. An increased number of machines and devices used in a mine caused a need for continuous monitoring of mining departments’ work. Monitoring of the extraction of hard coal beds is crucial for this process management, as it determines the proper course of the mining process. Hence, monitoring can be considered the most important element of the controlling process, especially in the area of mining process management in a mine. Effective monitoring and proper, quick reacting to any irregularities in this process have a significant influence on the production results of a mine.

  12. Preliminary results with a strip ionization chamber used as beam monitor for hadrontherapy treatments

    Science.gov (United States)

    Boriano, A.; Bourhaleb, F.; Cirio, R.; Cirrone, G. A. P.; Cuttone, G.; Donetti, M.; Garelli, E.; Giordanengo, S.; Luparia, A.; Marchette, F.; Peroni, C.; Raffaele, L.; Sabini, M. G.; Valastro, L.

    2006-01-01

    Preliminary results are presented from a test of a parallel plate ionization chamber with the anode segmented in strips (MOPI) to be used as a beam monitor for therapeutical treatments on the 62 MeV proton beam line of the INFN-LNS Superconducting Cyclotron. Ocular pathologies have been treated at the Catana facility since March 2002. The detector, placed downstream of the patient collimator, will allow the measurement of the relevant beam diagnostic parameters during treatment such as integrated beam fluence, for dose determination; the beam baricentre, width and asymmetry will be obtained from the fluence profile sampled with a resolution of about 100 Urn at a rate up to 1 kHz with no dead time. In this test, carried out at LNS, the detector has been exposed to different beam shapes and the integrated fluence derived by the measured beam profiles has been compared with that obtained with other dosimeters normally used for treatment. The skewness of the beam profile has been measured and shown to be suitable to on-line check variations of the beam shape.

  13. Interferometric Monitoring of Gamma-ray Bright AGNs I: Results of Single-epoch Multifrequency Observations

    CERN Document Server

    Lee, Sang-Sung; Algaba, Juan-Carlos; Zhao, Guang-Yao; Hodgson, Jeffrey A; Kim, Dae-Won; Park, Jongho; Kim, Jae-Young; Miyazaki, Atsushi; Byun, Do-Young; Kang, Sincheol; Kim, Jeong-Sook; Kim, Soon-Wook; Kino, Motoki; Trippe, Sascha

    2016-01-01

    We present results of single-epoch very long baseline interferometry (VLBI) observations of gamma-ray bright active galactic nuclei (AGNs) using the Korean VLBI Network (KVN) at 22, 43, 86, and 129~GHz bands, which are part of a KVN key science program, Interferometric Monitoring of Gamma-ray Bright AGNs (iMOGABA). We selected a total of 34 radio-loud AGNs of which 30 sources are gamma-ray bright AGNs with flux densities of $>6\\times10^{-10}$~ph~cm$^{-2}$~s$^{-1}$. Single-epoch multi-frequency VLBI observations of the target sources were conducted during a 24-hr session on 2013 November 19 and 20. All observed sources were detected and imaged at all frequency bands with or without a frequency phase transfer technique which enabled the imaging of 12 faint sources at 129~GHz, except for one source. Many of the target sources are resolved on milliarcsecond scales, yielding a core-jet structure with the VLBI core dominating the synchrotron emission on the milliarcsecond scale. CLEAN flux densities of the target s...

  14. Partial results summary for solar domestic hot water monitoring in Pennsylvania

    Science.gov (United States)

    Aungst, W. K.

    Installation procedures, monitoring practices, and results of performance evaluations of 50 HUD-sponsored residential solar flat plate collector systems studied in the field are summarized. The systems consisted of antifreeze, drain-down, and air freeze protection schemes, featured either one- or two-tank thermal storage, and were either roof- or ground-mounted. Residents kept daily records of water flow, temperature, kWh, and elapsed time. The HUD program goals were that one-half of the household daily water needs would be heated by the solar system. An average of 34.5% of the hot water energy was found, although a coefficient of performance of 1.40 was also found, compared to 0.78 and 0.82 for nonsolar water heaters. An average of 9% rate of return on investment was calculated for the solar systems, noting that system efficiencies ranged from 7-79.8%, and the rates of return ranged from 1-22.4%.

  15. First results from HAWC: monitoring the TeV gamma-ray sky

    Science.gov (United States)

    Lauer, Robert J.

    2015-03-01

    The High Altitude Water Cherenkov (HAWC) Observatory is a wide-field gamma-ray detector sensitive to primary energies between 100 GeV and 100 TeV. The array is being built at an altitude of 4100 m a.s.l. on the Sierra Negra volcano near Puebla, Mexico. Data taking has already started while construction continues, with the completion projected for early 2015. The design is optimized to detect extended air showers induced by gamma rays that pass through the array and to reconstruct the directions and energies of the primary photons. With a duty cycle close to 100% and a daily coverage of ~8 sr of the sky, HAWC will perform a survey of TeV emissions from many different sources. The northern active galactic nuclei will be monitored for up to 6 hours each day, providing unprecedented light curve coverage at energies comparable to those of imaging air Cherenkov telescopes. HAWC has been in scientific operation with more than 100 detector modules since August 2013. Here we present a preliminary look at the first results and discuss the efforts to integrate HAWC in multi-wavelength studies of extragalactic jets.

  16. REALITY AND EXPECTANCIES OF INDEPENDENT ASSESSMENT AND CERTIFICATION OF QUALIFICATIONS THE RESULTS OF MONITORING, AUTUMN 2014

    Directory of Open Access Journals (Sweden)

    Helen Breslav

    2015-10-01

    Full Text Available The monitoring of an independent assessment and certification of qualifications held by the Pastukhov Academy in the framework of the project of Federal Service for Supervision in the Sphere of Science and Education (Rosobrnadzor in the fall 2014 gave paradoxical results. On the one hand, the situation in the sphere of the independent assessment must be judged as barely satisfactory: certification bodies are poorly represented online, their number is insufficient, information is not enough, and plans are incorrect, best practices are also not enough. On the other hand, respondents welcomed development of the system of independent assessment. In the future, they expect to get significant benefits both for society as a whole and for individual professionals. The author proposes the ways to improve the situation and makes recommendations not only to bodies for the independent assessment and certification of qualifications, but also to other interested parties, in particular, professional associations and authorities in the field of education. The process of development of professional standards and participation in this process by various stakeholders are also considered.

  17. [Microdialysis of cutaneous free flaps to monitor results of maxillofacial surgery].

    Science.gov (United States)

    Brix, M; Muret, P; Mac-Mary, S; Ricbourg, B; Humbert, P

    2006-02-01

    The development of in vivo microdialysis has made it possible to monitor cutaneous free flaps in maxillo-facial surgery. A microprobe inserted in the free flap dermis collects a microdialysate enabling measurement of dermal metabolites such as glucose, lactate, pyruvate, or glycerol. The monitoring curves are predictive of ischemia-related tissue injury. Hourly measurements provide a reliable method for early diagnosis of venous or arterial thrombosis. Revision surgery can then be undertaken if needed to repair microanastomoses before clinical alteration. This technique has been compared with validated flaps monitoring systems such as temperature probe, transcutaneous oxygen tension monitoring, and laser Doppler flowmetry. Microdialysis has several advantages: objective measurements, different curves for venous and arterial thrombosis, early diagnosis. Accessibility to oral cavity or pharyngeal flaps requires careful clinical analysis (microprobe fixation, anatomy and choice of flap).

  18. Total knee arthroplasties performed with a mini-incision or a standard incision. Similar results at six months follow-up

    Directory of Open Access Journals (Sweden)

    Noriega-Fernandez Alfonso

    2010-02-01

    Full Text Available Abstract Background Minimal invasion surgery (MIS is a recent technique recommended for Total knee arthroplasty (TKA but demands an effort of the surgeons and the learning curve may be long. Methods Twenty six MIS-TKA were matched to 36 standard TKA with respect to age, sex, body mass index or preoperative score. All patients suffered from knee osteoarthritis, which had not improved with medical treatment and which presented a less than 10° deformity in the coronal and sagittal radiographic projections. At six months after the surgery a specific questionnaire was completed as well as the KSS (Knee Society rating scale, the generic short-form health questionnaire (SF-12 and a visual analogue scale (VAS. Results The MIS technique required more time of surgery (p Conclusions Minimal invasion surgery in total knee arthroplasty showed no improvement over a standard approach.

  19. Vascular endothelial growth factor Trap-Eye for macular edema secondary to central retinal vein occlusion: six-month results of the phase 3 COPERNICUS study.

    Science.gov (United States)

    Boyer, David; Heier, Jeffrey; Brown, David M; Clark, W Lloyd; Vitti, Robert; Berliner, Alyson J; Groetzbach, Georg; Zeitz, Oliver; Sandbrink, Rupert; Zhu, Xiaoping; Beckmann, Karola; Haller, Julia A

    2012-05-01

    To assess the efficacy and safety of intravitreal vascular endothelial growth factor (VEGF) Trap-Eye in eyes with macular edema secondary to central retinal vein occlusion (CRVO). Multicenter, randomized, prospective, controlled trial. One hundred eighty-nine eyes with macular edema secondary to CRVO. Eyes were randomized 3:2 to receive VEGF Trap-Eye 2 mg or sham injection monthly for 6 months. The proportion of eyes with a ≥15-letter gain or more in best-corrected visual acuity (BCVA) at week 24 (primary efficacy end point), mean changes in BCVA and central retinal thickness (CRT), and proportion of eyes progressing to neovascularization of the anterior segment, optic disc, or elsewhere in the retina. At week 24, 56.1% of VEGF Trap-Eye treated eyes gained 15 letters or more from baseline versus 12.3% of sham-treated eyes (P<0.001). The VEGF Trap-Eye treated eyes gained a mean of 17.3 letters versus sham-treated eyes, which lost 4.0 letters (P<0.001). Central retinal thickness decreased by 457.2 μm in eyes treated with VEGF Trap-Eye versus 144.8 μm in sham-treated eyes (P<0.001), and progression to any neovascularization occurred in 0 and 5 (6.8%) of eyes treated with VEGF Trap-Eye and sham-treated eyes, respectively (P = 0.006). Conjunctival hemorrhage, reduced visual acuity, and eye pain were the most common adverse events (AEs). Serious ocular AEs were reported by 3.5% of VEGF Trap-Eye patients and 13.5% of sham patients. Incidences of nonocular serious AEs generally were well balanced between both groups. At 24 weeks, monthly intravitreal injection of VEGF Trap-Eye 2 mg in eyes with macular edema resulting from CRVO improved visual acuity and CRT, eliminated progression resulting from neovascularization, and was associated with a low rate of ocular AEs related to treatment. Copyright © 2012 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  20. Radiographic results after plaster cast fixation for 10 days versus 1 month in reduced distal radius fractures: a prospective randomised study.

    Science.gov (United States)

    Christersson, Albert; Larsson, Sune; Östlund, Bengt; Sandén, Bengt

    2016-11-21

    The aim of this study was to examine whether reduced distal radius fractures can be treated with early mobilisation without affecting the radiographic results. In a prospective randomised study, 109 patients (mean age 65.8 (range 50-92)) with moderately displaced distal radius fractures were treated with closed reduction and plaster cast fixation for about 10 days (range 8-13 days) followed by randomisation to one of two groups: early mobilisation (n = 54, active group) or continued plaster cast fixation for another 3 weeks (n = 55, control group). For three patients in the active group (6%), treatment proved unsuccessful because of severe displacement of the fracture (n = 2) or perceived instability (n = 1). From 10 days to 1 month, i.e. the only period when the treatment differed between the two groups, the active group displaced significantly more in dorsal angulation (4.5°, p < 0.001), radial angulation (2.0°, p < 0.001) and axial compression (0.5 mm, p = 0.01) compared with the control group. However, during the entire study period (i.e. from admission to 12 months), the active group displaced significantly more than the controls only in radial angulation (3.2°, p = 0.002) and axial compression (0.7 mm, p = 0.02). Early mobilisation 10 days after reduction of moderately displaced distal radius fractures resulted in both an increased number of treatment failures and increased displacement in radial angulation and axial compression as compared with the control group. Mobilisation 10 days after reduction cannot be recommended for the routine treatment of reduced distal radius fractures. ClinicalTrail.gov, NCT02798614 . Retrospectively registered 16 June 2016.

  1. Effect of Early Everolimus-Facilitated Reduction of Tacrolimus on Efficacy and Renal Function in De Novo Liver Transplant Recipients: 24-Month Results for the North American Subpopulation

    Science.gov (United States)

    Chapman, William C.; Brown, Robert S.; Chavin, Kenneth D.; Sudan, Debra; Koneru, Baburao; Junge, Guido; Dong, Gaohong; Patel, Dharmesh; Teperman, Lewis; Fung, John J.

    2017-01-01

    Background A recent randomized phase III study of 719 de novo liver transplant recipients showed that early everolimus plus reduced-dose tacrolimus (EVR + rTAC) led to significantly better kidney function than standard TAC (TAC-C), without compromising efficacy. In that study, patients from North America (n = 211) had increased risk factors for posttransplant renal insufficiency at study start, relative to patients from Europe and rest of world (eg, worse renal function, more diabetes, older age). Methods A post hoc analysis was performed to assess whether these regional disparities affected study outcomes in North American patients. Results In this subpopulation, estimated glomerular filtration rates at randomization were higher in TAC-C over EVR + rTAC (76.4 vs 69.3 mL/min per 1.73 m2). Mean changes in estimated glomerular filtration rate values (mL/min per 1.73 m2) favored EVR + rTAC over TAC-C at months 12 (+3.7 vs −4.5; P = 0.032), 24 (+2.7 vs −6.6; P = 0.042), and 36 (+4.3 vs −8.1; P = 0.059). The composite efficacy endpoint of treated biopsy-proven acute rejection, graft loss, or death was 10.9%, 14.1%, and 14.1% for EVR + rTAC and 13.1%, 17.2%, and 19.3% for TAC-C at months 12, 24, and 36, respectively. Conclusions Although the North American cohort had more comorbidities, results were consistent with the overall population for efficacy and renal function. PMID:28121741

  2. Maternal Mental Health and Its Association with Infant Growth at 6 Months in Ethnic Groups: Results from the Born-in-Bradford Birth Cohort Study

    OpenAIRE

    Gemma D Traviss; West, Robert M.; House, Allan O

    2012-01-01

    OBJECTIVE: To identify factors associated with infant growth up to 6 months, with a particular focus on maternal distress, and to explore the effect of ethnicity on any relation between maternal distress and infant growth. METHODS: Cohort study recruiting White and Pakistani women in the United Kingdom (UK). Infant growth was measured at birth and 6 months. Standard assessment of mental health (GHQ-28) was undertaken in pregnancy (26-28 weeks gestation) and 6 months postpartum. Modelling incl...

  3. Computerised cognitive–behavioural therapy for depression in adolescents: feasibility results and 4-month outcomes of a UK randomised controlled trial

    Science.gov (United States)

    Wright, Barry; Tindall, Lucy; Littlewood, Elizabeth; Allgar, Victoria; Abeles, Paul; Trépel, Dominic; Ali, Shehzad

    2017-01-01

    Objectives Computer-administered cognitive–behavioural therapy (CCBT) may be a promising treatment for adolescents with depression, particularly due to its increased availability and accessibility. The feasibility of delivering a randomised controlled trial (RCT) comparing a CCBT program (Stressbusters) with an attention control (self-help websites) for adolescent depression was evaluated. Design Single centre RCT feasibility study. Setting The trial was run within community and clinical settings in York, UK. Participants Adolescents (aged 12–18) with low mood/depression were assessed for eligibility, 91 of whom met the inclusion criteria and were consented and randomised to Stressbusters (n=45) or websites (n=46) using remote computerised single allocation. Those with comorbid physical illness were included but those with psychosis, active suicidality or postnatal depression were not. Interventions An eight-session CCBT program (Stressbusters) designed for use with adolescents with low mood/depression was compared with an attention control (accessing low mood self-help websites). Primary and secondary outcome measures Participants completed mood and quality of life measures and a service Use Questionnaire throughout completion of the trial and 4 months post intervention. Measures included the Beck Depression Inventory (BDI) (primary outcome measure), Mood and Feelings Questionnaire (MFQ), Spence Children's Anxiety Scale (SCAS), the EuroQol five dimensions questionnaire (youth) (EQ-5D-Y) and Health Utility Index Mark 2 (HUI-2). Changes in self-reported measures and completion rates were assessed by treatment group. Results From baseline to 4 months post intervention, BDI scores and MFQ scores decreased for the Stressbusters group but increased in the website group. Quality of life, as measured by the EQ-5D-Y, increased for both groups while costs at 4 months were similar to baseline. Good feasibility outcomes were found, suggesting the trial process to be

  4. Randomised trial of coronary intervention with antibody against platelet IIb/IIIa integrin for reduction of clinical restenosis: results at six months. The EPIC Investigators.

    Science.gov (United States)

    Topol, E J; Califf, R M; Weisman, H F; Ellis, S G; Tcheng, J E; Worley, S; Ivanhoe, R; George, B S; Fintel, D; Weston, M

    1994-04-09

    Restenosis after coronary angioplasty occurs in at least 30% of patients in the first six months and, as yet, there is no known treatment to decrease this event. We tested a monoclonal antibody Fab fragment (c7E3) directed against the platelet glycoprotein IIb/IIIa integrin, the receptor mediating the final common pathway of platelet aggregation, to see whether it reduced the frequency of clinical restenosis. Patients who had unstable angina, recent or evolving myocardial infarction, or high-risk angiographic morphology, were randomised to receive c7E3 bolus and a 12 hour infusion of c7E3 (708 patients), c7E3 bolus and placebo infusion (695 patients), or placebo bolus and placebo infusion (696 patients). With maintenance of the double-blind state, patients were followed-up for at least 6 months to determine the need for repeat angioplasty or surgical coronary revascularisation and the occurrence of ischaemic events. By 30 days, 12.8% of placebo bolus/placebo infusion patients had had a major ischaemic event (death, myocardial infarction, urgent revascularisation), compared with 8.3% of c7E3 bolus/c7E3 infusion patients, yielding a 4.5% difference (35% reduction, p = 0.008). At 6 months, the absolute difference in patients with major ischaemic event or elective revascularisation was 8.1% between placebo bolus/placebo infusion and c7E3 bolus/c7E3 infusion patients (35.1% vs 27.0%; 23% reduction p = 0.001). The favourable long-term effect was mainly due to less need for bypass surgery or repeat angioplasty in patients with an initial successful procedure, since need for repeat target vessel revascularisation was 26% less for c7E3 bolus/c7E3 infusion than for placebo treatment (16.5% vs 22.3%; p = 0.007). The c7E3 bolus/placebo infusion group had an intermediate outcome which was not significantly better than that of the placebo bolus/placebo infusion group. These results extend the benefit of c7E3 bolus/c7E3 infusion from reducing abrupt closure and acute

  5. Results of fractional ablative facial skin resurfacing with the erbium:yttrium-aluminium-garnet laser 1 week and 2 months after one single treatment in 30 patients.

    Science.gov (United States)

    Trelles, Mario A; Mordon, Serge; Velez, Mariano; Urdiales, Fernando; Levy, Jean Luc

    2009-03-01

    The erbium:yttrium-aluminium-garnet (Er:YAG) laser has recently been used in the fractional resurfacing of photo-aged skin. Our study evaluated the results after one single session of fractional resurfacing with Er:YAG. Thirty women participated in the study, with an average age of 46 years, skin types from II to IV, and wrinkle grades I to III. The 2,940 nm Er:YAG system used (Pixel, Alma Laser, Israel) had variable pulse durations (1 ms to 2 ms) and energy densities (800 mJ/cm(2) to 1,400 mJ/cm(2)) which, together with the number of passes (four to eight), were selected as a function of wrinkle severity. All patients received only one treatment. Postoperative side effects were evaluated. The number of wrinkles was documented with clinical photography and was scored. Histological assessment was carried out on two patients before and 2 months after treatment. All patients completed the study. Of the patients, 93% reported good or very good improvement of the degree of their wrinkles, with a satisfaction index of 83%. Pain was not a problem during treatment, and there were no side effects except for in one phototype IV patient, who had hyperpigmentation. Histology 2 months after the single treatment demonstrated younger morphology of both the epidermis and dermis, with improvement of the pretreatment typical elastotic appearance. At the parameters used in our study, only one treatment session of Er:YAG laser could achieve effective skin rejuvenation, with effects recognized in both the dermis and, more importantly, the epidermis. This regimen offers an interesting alternative to the conventional approach of multi-session fractional resurfacing.

  6. Supervised exercise versus primary stenting for claudication resulting from aortoiliac peripheral artery disease: six-month outcomes from the claudication: exercise versus endoluminal revascularization (CLEVER) study.

    Science.gov (United States)

    Murphy, Timothy P; Cutlip, Donald E; Regensteiner, Judith G; Mohler, Emile R; Cohen, David J; Reynolds, Matthew R; Massaro, Joseph M; Lewis, Beth A; Cerezo, Joselyn; Oldenburg, Niki C; Thum, Claudia C; Goldberg, Suzanne; Jaff, Michael R; Steffes, Michael W; Comerota, Anthony J; Ehrman, Jonathan; Treat-Jacobson, Diane; Walsh, M Eileen; Collins, Tracie; Badenhop, Dalynn T; Bronas, Ulf; Hirsch, Alan T

    2012-01-03

    Claudication is a common and disabling symptom of peripheral artery disease that can be treated with medication, supervised exercise (SE), or stent revascularization (ST). We randomly assigned 111 patients with aortoiliac peripheral artery disease to receive 1 of 3 treatments: optimal medical care (OMC), OMC plus SE, or OMC plus ST. The primary end point was the change in peak walking time on a graded treadmill test at 6 months compared with baseline. Secondary end points included free-living step activity, quality of life with the Walking Impairment Questionnaire, Peripheral Artery Questionnaire, Medical Outcomes Study 12-Item Short Form, and cardiovascular risk factors. At the 6-month follow-up, change in peak walking time (the primary end point) was greatest for SE, intermediate for ST, and least with OMC (mean change versus baseline, 5.8±4.6, 3.7±4.9, and 1.2±2.6 minutes, respectively; POMC, P=0.02 for ST versus OMC, and P=0.04 for SE versus ST). Although disease-specific quality of life as assessed by the Walking Impairment Questionnaire and Peripheral Artery Questionnaire also improved with both SE and ST compared with OMC, for most scales, the extent of improvement was greater with ST than SE. Free-living step activity increased more with ST than with either SE or OMC alone (114±274 versus 73±139 versus -6±109 steps per hour), but these differences were not statistically significant. SE results in superior treadmill walking performance than ST, even for those with aortoiliac peripheral artery disease. The contrast between better walking performance for SE and better patient-reported quality of life for ST warrants further study. URL: http://clinicaltrials.gov/ct/show/NCT00132743?order=1. Unique identifier: NCT00132743.

  7. A randomized, controlled trial of group cognitive-behavioral therapy for compulsive buying disorder: posttreatment and 6-month follow-up results.

    Science.gov (United States)

    Mueller, Astrid; Mueller, Ulrike; Silbermann, Andrea; Reinecker, Hans; Bleich, Stefan; Mitchell, James E; de Zwaan, Martina

    2008-07-01

    The purpose of this study was to conduct a randomized trial comparing the efficacy of a group cognitive-behavioral therapy (CBT) intervention designed for the treatment of compulsive buying disorder to a waiting list control (WLC) group. Thirty-one patients with compulsive buying problems according to the criteria developed by McElroy et al. were assigned to receive active treatment (12 weekly sessions and 6-month follow-up) and 29 to the WLC group. The treatment was specifically aimed at interrupting and controlling the problematic buying behavior, establishing healthy purchasing patterns, restructuring maladaptive thoughts and negative feelings associated with shopping and buying, and developing healthy coping skills. Primary outcome measures were the Compulsive Buying Scale (CBS), the Yale-Brown Obsessive Compulsive Scale-Shopping Version (YBOCS-SV), and the German Compulsive Buying Scale (G-CBS). Secondary outcome measures were the Symptom Checklist-90-Revised (SCL-90-R), the Barratt Impulsiveness Scale (BIS-11), and the Saving Inventory-Revised (SI-R). The study was completed between November 2003 and May 2007 at the University Hospital of Erlangen, Bavaria, Germany. Multivariate analysis revealed significant differences between the CBT and the WLC groups on the primary outcome variables (outcome-by-time-by-group effect, Pillai's trace, F = 6.960, df = 1, p = .002). The improvement was maintained during the 6-month follow-up. The treatment did not affect other psychopathology, e.g., compulsive hoarding, impulsivity, or SCL-90-R scores. We found that lower numbers of visited group therapy sessions and higher pretreatment hoarding traits as measured with the SI-R total score were significant predictors for nonresponse. The results suggest that a disorder-specific cognitive-behavioral intervention can significantly impact compulsive buying behavior.

  8. Results of hydrologic monitoring on landslide-prone coastal bluffs near Mukilteo, Washington

    Science.gov (United States)

    Smith, Joel B.; Baum, Rex L.; Mirus, Benjamin B.; Michel, Abigail R.; Stark, Ben

    2017-08-31

    A hydrologic monitoring network was installed to investigate landslide hazards affecting the railway corridor along the eastern shore of Puget Sound between Seattle and Everett, near Mukilteo, Washington. During the summer of 2015, the U.S. Geological Survey installed monitoring equipment at four sites equipped with instrumentation to measure rainfall and air temperature every 15 minutes. Two of the four sites are installed on contrasting coastal bluffs, one landslide scarred and one vegetated. At these two sites, in addition to rainfall and air temperature, volumetric water content, pore pressure, soil suction, soil temperature, and barometric pressure were measured every 15 minutes. The instrumentation was designed to supplement landslide-rainfall thresholds developed by the U.S. Geological Survey with a long-term goal of advancing the understanding of the relationship between landslide potential and hydrologic forcing along the coastal bluffs. Additionally, the system was designed to function as a prototype monitoring system to evaluate criteria for site selection, instrument selection, and placement of instruments. The purpose of this report is to describe the monitoring system, present the data collected since installation, and describe significant events represented within the dataset, which is published as a separate data release. The findings provide insight for building and configuring larger, modular monitoring networks.

  9. Real-world effectiveness of daily teriparatide in Japanese patients with osteoporosis at high risk for fracture: final results from the 24-month Japan Fracture Observational Study (JFOS).

    Science.gov (United States)

    Soen, Satoshi; Fujiwara, Saeko; Takayanagi, Ryoichi; Kajimoto, Kenta; Tsujimoto, Mika; Kimura, Shuichi; Sato, Masayo; Krege, John H; Enomoto, Hiroyuki

    2017-11-01

    The Japan Fracture Observational Study (JFOS), a prospective observational study, investigated the real-world effectiveness of daily teriparatide to reduce clinical fracture risk in osteoporotic patients. In routine clinical practice, Japanese patients initiated on teriparatide 20 μg/day by subcutaneous injection were enrolled. The primary end-point was the rate of clinical fractures at 6-month intervals over 24 months. Bone mineral density (BMD), procollagen type 1 aminoterminal propeptide (P1NP), back pain, and health-related quality-of-life (HRQoL) information was collected. Of 1,996 patients at baseline, 90.1% were female, and mean age was 76.9 years. Teriparatide persistence at 12 and 24 months was 68.0% and 51.6%, respectively. Compared to the first 6-month treatment interval, the odds ratio of fractures decreased by 56.4% during 6-12 months, 51.6% during 12-18 months, and 58.8% during 18-24 months (all p < .01). After 24 months, BMD increased by 17.2% (lumbar spine) and 7.9% (total hip). After 6 months, P1NP levels increased by 259.3%. A reduction in back pain (100 mm visual analog scale) of 16.1 mm at 3 months was maintained through 24 months. HRQoL (pain, daily living activities, general health) improved by ≥10% at each post-baseline time point. Of 279 (14.6%) patients with ≥1 adverse event (AE), 71 (3.7%) experienced ≥1 drug-related AE (investigator assessed), including nausea (0.7%), dizziness (0.4%), and decreased appetite (0.3%). Osteosarcoma was not reported; there were no new safety signals. JFOS demonstrated effectiveness of teriparatide 20 μg/day to reduce the risk of clinical fractures in Japanese patients in a real-world setting.

  10. The impact of a port on the surrounding seashores based on the 13-year monitoring results

    Science.gov (United States)

    Tõnisson, Hannes; Orviku, Kaarel; Kont, Are

    2017-04-01

    The study was carried out in the vicinity of Sillamäe town and industrial port, located on the north-eastern coast of Estonia in the south-eastern part of the Gulf of Finland (The Baltic Sea). Sillamäe was potentially one of the most serious threats for the whole Baltic Sea environment. The town was founded together with the construction of a highly specialized chemical and metallurgy plant in 1946, where fuel rods and nuclear materials for the Soviet nuclear power plants and weapons were produced. The current study is focusing on the shore processes and the coastal sea fronting Sillamäe. The town is located east of the port. It is the region with the highest potential impact of the port. Until the town was founded and the factory with its nuclear waste depository was constructed, the shores near the town were described as one litho-dynamic system with a good natural balance. Major human influence (construction of the port, waste depository, etc.) and additionally climate warming has taken place since then. The shores in front of the nuclear waste depository are well protected today. However, the rapidly expanding port is the major obstacle of the longshore sediment transport since 2001. The aim of the study is to analyze the impact of the port to the changes in coastal evolution and sediment budget in the vicinity of the port based on the regular monitoring results. The dynamics of the seashores was assessed using remote methods and in situ measurements. Remote methods included the analyses of shoreline changes and changes in scarp positions in space and time using orthophotos. The study is also based on the measurements of scarp edges, shorelines and shore profiles conducted in 2004-2016. The measurements were carried out using Leica GS09 RTK-GPS and Leica level. The volume of sediments in the active zone of each profile was calculated. The active zone was defined as the zone from the mean shoreline to the elevation where storm waves were still able to

  11. Kilovoltage Intrafraction Monitoring for Prostate Intensity Modulated Arc Therapy: First Clinical Results

    Energy Technology Data Exchange (ETDEWEB)

    Ng, Jin Aun [Radiation Physics Laboratory, Sydney Medical School and Institute of Medical Physics, School of Physics, University of Sydney, New South Wales (Australia); Institute of Medical Physics, School of Physics, University of Sydney, New South Wales (Australia); Booth, Jeremy T. [Institute of Medical Physics, School of Physics, University of Sydney, New South Wales (Australia); Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, New South Wales (Australia); Poulsen, Per R.; Fledelius, Walther; Worm, Esben Schjodt [Department of Oncology, Aarhus University Hospital, Denmark, and Institute of Clinical Medicine, Aarhus University (Denmark); Eade, Thomas; Hegi, Fiona; Kneebone, Andrew [Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, New South Wales (Australia); Kuncic, Zdenka [Institute of Medical Physics, School of Physics, University of Sydney, New South Wales (Australia); Keall, Paul J., E-mail: paul.keall@sydney.edu.au [Radiation Physics Laboratory, Sydney Medical School and Institute of Medical Physics, School of Physics, University of Sydney, New South Wales (Australia)

    2012-12-01

    Purpose: Most linear accelerators purchased today are equipped with a gantry-mounted kilovoltage X-ray imager which is typically used for patient imaging prior to therapy. A novel application of the X-ray system is kilovoltage intrafraction monitoring (KIM), in which the 3-dimensional (3D) tumor position is determined during treatment. In this paper, we report on the first use of KIM in a prospective clinical study of prostate cancer patients undergoing intensity modulated arc therapy (IMAT). Methods and Materials: Ten prostate cancer patients with implanted fiducial markers undergoing conventionally fractionated IMAT (RapidArc) were enrolled in an ethics-approved study of KIM. KIM involves acquiring kV images as the gantry rotates around the patient during treatment. Post-treatment, markers in these images were segmented to obtain 2D positions. From the 2D positions, a maximum likelihood estimation of a probability density function was used to obtain 3D prostate trajectories. The trajectories were analyzed to determine the motion type and the percentage of time the prostate was displaced {>=}3, 5, 7, and 10 mm. Independent verification of KIM positional accuracy was performed using kV/MV triangulation. Results: KIM was performed for 268 fractions. Various prostate trajectories were observed (ie, continuous target drift, transient excursion, stable target position, persistent excursion, high-frequency excursions, and erratic behavior). For all patients, 3D displacements of {>=}3, 5, 7, and 10 mm were observed 5.6%, 2.2%, 0.7% and 0.4% of the time, respectively. The average systematic accuracy of KIM was measured at 0.46 mm. Conclusions: KIM for prostate IMAT was successfully implemented clinically for the first time. Key advantages of this method are (1) submillimeter accuracy, (2) widespread applicability, and (3) a low barrier to clinical implementation. A disadvantage is that KIM delivers additional imaging dose to the patient.

  12. Planetary boundary layer (PBL) monitoring by means of two laser radar systems: experimental results and comparison

    Science.gov (United States)

    Bellecci, C.; Gaudio, P.; Gelfusa, M.; Malizia, A.; Richetta, M.; Serafini, C.; Ventura, P.

    2010-10-01

    The PBL is the lower layer of the atmosphere that is sensitive to the effect of the Earths surface, it controls the flow of heat and momentum between the surface and the free atmosphere, thus playing a key role in atmospheric circulation. At University of Rome "Tor Vergata", Quantum Electronic and Plasma Laboratories (EQP), two mobile Light Detection and Ranging (LIDAR) systems have been developed. With these systems the monitoring of the Planetary Boundary Layer (PBL) has been performed. The first mobile Lidar system is based on a pulsed Nd:YAG Q-Switched laser source operating at three wavelengths: 1064 nm, 532 nm and 355 nm. Acquiring the elastic backscattered signals, it has been possible to estimate the aerosolitic backscattering coefficient at the aim to reconstruct the vertical aerosol profiles. The second one is a Differential Absorption Lidar system (DIAL), composed by a CO2 laser, working in the window spectral range between 9 and 11μm. With this system it has been estimated the water vapour concentration in the PBL region using the two wavelengths 10R20 (10.591 μm) and 10R18 (10.571 μm), which represent, respectively, the absorbing wavelength and non-absorbing one of the water molecule. The comparison of the backscattered radiation at these wavelengths yields the trace gas number density as a function of distance along the field-of-view of the receiving telescope. Diurnal and nocturnal measurements have been performed simultaneity using the two Lidar/Dial systems. Vertical profiles of the aerosolitic backscattering coefficient and water vapour concentration profiles have been estimated. The results and their comparison will be present in this work.

  13. Radiological monitoring results of the ambient environment around Qinshan Nuclear Power Plant

    Institute of Scientific and Technical Information of China (English)

    ZHANG Rong-Suo; ZENG Guang-Jian; JIANG Rang-Rong; YE Ji-Da; XIANG Yuan-Yi; HUANG Ren-Jie; CAO Zhong-Gang

    2004-01-01

    A plan of surveillance monitoring Qinshan Nuclear Power Plant (QNPP) has been implemented since 1992, the objective of which is to establish the database of environmental radiation information around QNPP, and to detect any unplanned discharge of radioactive materials from QNPP. This paper presents the nonitoring results for radionuclide concentrations in the environmental matrices before and after QNPP operation. The radionuclide concentrations in vegetation, food, atmosphere, soil and littoral soil samples have been determined. After operation of QNPP, the mean values of 137Cs, 90Sr and 3H in water are 0.6, 4.9 mBq/L and 1.7 Bq/L, respectively; the mean values of 137Cs in soil and littoral soil are 3.5 and 2.7 Bq/kg, respectively; the mean values of 137Cs in rice, green cabbage,meat, mullet, milk and tea are 0.033, 0.039, 0.081, 0.069, 0.018 and 0.62 Bq/kg, respectively: the mean values of 90Sr in rice, green cabbage and tea are 0.081, 0.315 and 4.1 Bq/kg, respectively: gross β activity in fallout is 0.9 Bq.m-2.d-1. Compared with the data before QNPP's operation, no significant difference has heen observed in the radioactivity of 137Cs, 90Sr, 3H and the gross β activity in ambient environmental matrices from 1992 to 2001, and there are only some fluctuations within the range of background.

  14. Clinical Benefits of an Adherence Monitoring Program in the Management of Secondary Hyperparathyroidism with Cinacalcet: Results of a Prospective Randomized Controlled Study

    Directory of Open Access Journals (Sweden)

    Valentina Forni Ogna

    2013-01-01

    Full Text Available Background/Aims. One of the causes of uncontrolled secondary hyperparathyroidism (sHPT is patient’s poor drug adherence. We evaluated the clinical benefits of an integrated care approach on the control of sHPT by cinacalcet. Methods. Prospective, randomized, controlled, multicenter, open-label study. Fifty hemodialysis patients on a stable dose of cinacalcet were randomized to an integrated care approach (IC or usual care approach (UC. In the IC group, cinacalcet adherence was monitored using an electronic system. Results were discussed with the patients in motivational interviews, and drug prescription adapted accordingly. In the UC group, drug adherence was monitored, but results were not available. Results. At six months, 84% of patients in the IC group achieved recommended iPTH targets versus 55% in the UC group (. The mean cinacalcet taking adherence improved by 10.8% in the IC group and declined by 5.3% in the UC group (. Concomitantly, the mean dose of cinacalcet was reduced by 7.2 mg/day in the IC group and increased by 6.4 mg/day in the UC group (. Conclusions. The use of a drug adherence monitoring program in the management of sHPT in hemodialysis patients receiving cinacalcet improves drug adherence and iPTH control and allows a reduction in the dose of cinacalcet.

  15. Clinical Benefits of an Adherence Monitoring Program in the Management of Secondary Hyperparathyroidism with Cinacalcet: Results of a Prospective Randomized Controlled Study

    Science.gov (United States)

    Forni Ogna, Valentina; Pruijm, Menno; Zweiacker, Carole; Wuerzner, Grégoire; Tousset, Eric; Burnier, Michel

    2013-01-01

    Background/Aims. One of the causes of uncontrolled secondary hyperparathyroidism (sHPT) is patient's poor drug adherence. We evaluated the clinical benefits of an integrated care approach on the control of sHPT by cinacalcet. Methods. Prospective, randomized, controlled, multicenter, open-label study. Fifty hemodialysis patients on a stable dose of cinacalcet were randomized to an integrated care approach (IC) or usual care approach (UC). In the IC group, cinacalcet adherence was monitored using an electronic system. Results were discussed with the patients in motivational interviews, and drug prescription adapted accordingly. In the UC group, drug adherence was monitored, but results were not available. Results. At six months, 84% of patients in the IC group achieved recommended iPTH targets versus 55% in the UC group (P = 0.04). The mean cinacalcet taking adherence improved by 10.8% in the IC group and declined by 5.3% in the UC group (P = 0.02). Concomitantly, the mean dose of cinacalcet was reduced by 7.2 mg/day in the IC group and increased by 6.4 mg/day in the UC group (P = 0.03). Conclusions. The use of a drug adherence monitoring program in the management of sHPT in hemodialysis patients receiving cinacalcet improves drug adherence and iPTH control and allows a reduction in the dose of cinacalcet. PMID:23971019

  16. Clinical evaluation of a novel dental implant system as single implants under immediate loading conditions - 4-month post-loading results from a multicentre randomised controlled trial.

    Science.gov (United States)

    Esposito, Marco; Trullenque-Eriksson, Anna; Blasone, Rodolfo; Malaguti, Giuliano; Gaffuri, Cristiano; Caneva, Marco; Minciarelli, Armando; Luongo, Giuseppe

    To evaluate the safety and clinical effectiveness of a novel dental implant system (GENESIS Implant System, Keystone Dental, Massachusetts, USA) using another dental implant system by the same manufacturer as a control (PRIMA Implant System, Keystone Dental). A total of 53 patients requiring at least two single crowns had their sites randomised according to a split-mouth design to receive both implant systems at six centres. If implants could be placed with a torque superior to 40 Ncm they were to be loaded immediately with provisional crowns, otherwise after 3 months of submerged healing. Provisional crowns were replaced by definitive crowns 4 months after initial loading, when the follow-up period for the initial part of this study was completed. Outcome measures were crown/implant failures, complications, pink esthetic score (PES), peri-implant marginal bone level changes, plaque score, marginal bleeding, patients and preference of the clinician. In total 53 PRIMA and 53 GENESIS implants were placed. Three patients dropped out but all of the remaining patients were followed up to 4-months post-loading. No PRIMA implant failed whereas four GENESIS implants failed. Only two complications were reported for PRIMA implants. There were no statistically significant differences for crown/implant failures (difference in proportions = 0.080; P (McNemar test) = 0.125) and complications (difference in proportions = -0.04; P (McNemar test) = 0.500) between the implant systems. There were no differences at 4-months post-loading for plaque (difference = -0.54, 95% CI: -3.01 to 1.93; P (Paired t-test) = 0.660), marginal bleeding (difference = -3.8, 95% CI: -7.63 to 0.019; P (Paired t-test) = 0.051), PES (difference = 0.47, 95% CI: -0.56 to 1.50; P (Paired t-test) = 0.365) and marginal bone level changes (difference in mm = -0.04, 95% CI: -0.33 to 0.26; P (Paired t-test) = 0.795). The majority of the patients (46) had no

  17. [Monitoring populations of rodent reservoirs of zoonotic diseases. Projects, aims and results].

    Science.gov (United States)

    Jacob, J; Ulrich, R G; Freise, J; Schmolz, E

    2014-05-01

    Rodents can harbor and transmit pathogens that can cause severe disease in humans, companion animals and livestock. Such zoonotic pathogens comprise more than two thirds of the currently known human pathogens. The epidemiology of some zoonotic pathogens, such as hantaviruses, can be linked to the population dynamics of the rodent host. In this case, during an outbreak of the rodent host population many human infections may occur. In other rodent-borne zoonotic diseases such phenomena are not known and in many cases the rodent host specificity of a given pathogen is unclear. The monitoring of relevant rodent populations and of the rodent-borne zoonotic pathogens is essential to (1) understand the distribution and epidemiology of pathogens and (2) develop forecasting tools to predict outbreaks of zoonoses. Presently, there are no systematic long-term monitoring programs in place for zoonoses in Germany. Rodent monitoring activities are largely restricted to the plant protection sector, such as for the common vole (Microtus arvalis) and forest-damaging rodents. However, during the last 10-15 years a number of specific research projects have been initiated and run for a few years and Norway rat (Rattus norvegicus) monitoring has been implemented in Hamburg and Lower Saxony. Based on close cooperation of federal and state authorities and research institutions these efforts could be utilized to gain information about the distribution and importance of rodent-borne zoonoses. Nevertheless, for the integration of rodent population dynamics and zoonotic disease patterns and especially for developing predictive models, long-term monitoring is urgently required. To establish a systematic long-term monitoring program, existing networks and cooperation need to be used, additional collaborators (e.g., pest control operators) should be included and synergetic effects of different scientific fields should be utilized.

  18. Individual External Dose Monitoring of All Citizens of Date City by Passive Dosimeter 5 to 52 Months After the Fukushima NPP Accident (series): 1. Comparison of Individual Dose with Ambient Dose Rate Monitored by Aircraft Surveys

    CERN Document Server

    Hayano, Ryugo

    2016-01-01

    Date (d\\textschwa 'te) City in Fukushima Prefecture has conducted a population-wide individual dose monitoring program after the Fukushima Daiichi Nuclear Power Plant Accident, which provides a unique and comprehensive data set of the individual doses of citizens. The relationship between the individual doses and the corresponding ambient doses assessed from airborne surveys was examined. The results show that the individual doses were about 0.15 times the ambient doses, which were a quarter of the value employed by the Japanese government, throughout the period of the airborne surveys used. The knowledge obtained in this study could enable the prediction of individual doses in the early phase of future radiological accidents involving large-scale contamination.

  19. Individual external dose monitoring of all citizens of Date City by passive dosimeter 5 to 51 months after the Fukushima NPP accident (series): 1. Comparison of individual dose with ambient dose rate monitored by aircraft surveys.

    Science.gov (United States)

    Miyazaki, Makoto; Hayano, Ryugo

    2016-12-06

    Date (da'te) City in Fukushima Prefecture has conducted a population-wide individual dose monitoring program after the Fukushima Daiichi Nuclear Power Plant Accident, which provides a unique and comprehensive data set of the individual doses of citizens. The purpose of this paper, the first in the series, is to establish a method for estimating effective doses based on the available ambient dose rate survey data. We thus examined the relationship between the individual external doses and the corresponding ambient doses assessed from airborne surveys. The results show that the individual doses were about 0.15 times the ambient doses, the coefficient of 0.15 being a factor of 4 smaller than the value employed by the Japanese government, throughout the period of the airborne surveys used. The method obtained in this study could aid in the prediction of individual doses in the early phase of future radiological accidents involving large-scale contamination.

  20. Results from the Blazar Monitoring Campaign at the Whipple 10m Gamma-ray Telescope

    CERN Document Server

    Steele, David; Charlot, P; Kurtanidze, O; Lahteenmaki, A; Montaruli, T; Sadun, A C; Villata, M

    2007-01-01

    In September 2005, the observing program of the Whipple 10 m gamma-ray telescope was redefined to be dedicated almost exclusively to AGN monitoring. Since then the five Northern Hemisphere blazars that had already been detected at Whipple are monitored routinely each night that they are visible. Thanks to the efforts of a large number of multiwavelength collaborators, the first year of this program has been very successful. We report here on the analysis of Markarian 421 observations taken from November, 2005 to May, 2006 in the gamma-ray, X-ray, optical and radio bands.

  1. Optimization in mammography - monthly monitoring of image quality at the state of Minas Gerais, Brazil; Otimizacao em mamografia - monitoramento mensal da qualidade da imagem no estado de Minas Gerais, Brasil

    Energy Technology Data Exchange (ETDEWEB)

    Joana, Georgia S.; Andrade, Mauricio C. de; Silva, Sabrina D. da; Silva, Rafael R. da; Cesar, Adriana C.Z.; Oliveira, Mauricio de, E-mail: georgia.santos@saude.mg.gov.b, E-mail: mauricio.cavalcanti@saude.mg.gov.b, E-mail: adrianac@saude.mg.gov.b, E-mail: mauricio.oliveira@saude.mg.gov.b [Secretaria de Estado da Saude de Minas Gerais (SVS/SES-MG), Belo Horizonte, MG (Brazil). Superintendencia de Vigilancia Sanitaria; Oliveira, Marcio A.; Nogueira, Maria do S., E-mail: marcio.alves@saude.mg.gov.b, E-mail: mnogue@cdtn.b [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil); Peixoto, Joao E. [Instituto Nacional de Cancer (INCA), Rio de Janeiro, RJ (Brazil)

    2011-07-01

    The State Program of Quality Control in Mammography (PECQMamo) of the state of Minas Gerais was established in 2004 and consists of tests for evaluation of image quality and performance of equipment used in the diagnosis of breast cancer, and evaluation the infrastructure of mammography centers. The monthly monitoring of image quality in mammography is part of this program that has been executed since May 2009 with a character essentially educational. In the assessment of individual services that participate in the monthly monitoring, there was an increased percentage of average annual compliance from 2009 to 2010 in all 85 services with the exception of one service. Therefore, evolution of the performance of the services evaluated, since the program began, shows a positive impact on the numbers, confirming the relevance of this type of operation of Sanitary Surveillance in the area of quality in mammography. (author)

  2. Reduced incidence of atrial fibrillation after cardiac surgery by continuous wireless monitoring of oxygen saturation on the normal ward and resultant oxygen therapy for hypoxia.

    Science.gov (United States)

    Kisner, Dilek; Wilhelm, Markus J; Messerli, Michael S; Zünd, Gregor; Genoni, Michele

    2009-01-01

    Monitoring of cardiac surgical patients after transfer from the intensive care unit to the normal ward is incomplete. Undetected hypoxia, however, is known to be a risk factor for occurrence of atrial fibrillation. We have utilized Auricall for continuous wireless monitoring of oxygen saturation and heart rate until discharge. The object of the study was to analyze if oxygen therapy as a result of Auricall alerts of hypoxia can decrease the incidence of postoperative atrial fibrillation. Auricall is a wireless portable pulse oximeter. An alert is generated depending on preset threshold values (heart rate, oxygen saturation). Over a period of 6 months, 119 patients were monitored with the Auricall following coronary artery bypass graft and/or valve surgery. Oxygen therapy was started subsequent to an oxygen saturation below 90%. These patients were compared with a cohort of 238 patients from the time period before availability of Auricall. The patient characteristics were comparable in both groups. In a retrospective study, the incidence of atrial fibrillation was measured in both groups. The postoperative AF was observed in 22/119 patients (18%) in group I and in 66/238 patients (28%) in group II. This difference between the two groups approached significance (p=0.056). In the subgroup of patients with coronary artery bypass graft with our without simultaneous valve surgery (n=312), Auricall monitoring resulted in a significantly reduced incidence of atrial fibrillation (14% vs 26%, p=0.016). Continuous monitoring of oxygen saturation on the normal ward and subsequent oxygen therapy for hypoxia can reduce the incidence of atrial fibrillation in a subgroup of patients after cardiac surgery. Prospective randomized trials are warranted to confirm these data.

  3. Water balance of rice plots under three different water treatments: monitoring activity and experimental results

    Science.gov (United States)

    Chiaradia, Enrico Antonio; Romani, Marco; Facchi, Arianna; Gharsallah, Olfa; Cesari de Maria, Sandra; Ferrari, Daniele; Masseroni, Daniele; Rienzner, Michele; Battista Bischetti, Gian; Gandolfi, Claudio

    2014-05-01

    input) were calculated for each treatment. The outcomes show that the water application efficiencies of all treatments were higher in 2013 than in 2012 (by 23%, 25% and 4% for FLD, 3L-FLD, and IRR respectively). These results could be ascribed to the higher groundwater level observed in 2013 (about 10-15 cm closer to the soil surface), likely due to the conversion of the field beyond the monitored plots from soybean to flooded rice. Moreover, a small increase of the water application efficiency of 3L-FLD was found if compared to FLD (3% on average), while the water application efficiency of IRR was, on average, higher by 67% compared to FLD. The good performance of IRR is related to lower percolation rates and a relevant contribution of capillary rise due to the shallow groundwater table maintained by the continuous submergence of the surrounding paddy fields. The performed experiment highlighted that significant improvement in the water use efficiency at the field scale can be achieved. However, a widespread adoption of water regimes different from continuous flooding should be carefully evaluated by a larger-scale approach since a consequent drop in the groundwater table depth could have repercussions on the potential gains themselves.

  4. First results of geodetic deformation monitoring after commencement of CO2 injection at the Aquistore underground CO2 storage site

    Science.gov (United States)

    Craymer, M.; White, D.; Piraszewski, M.; Zhao, Y.; Henton, J.; Silliker, J.; Samsonov, S.

    2015-12-01

    Aquistore is a demonstration project for the underground storage of CO2 at a depth of ~3350 m near Estevan, Saskatchewan, Canada. An objective of the project is to design, adapt, and test non-seismic monitoring methods that have not been systematically utilized to date for monitoring CO2 storage projects, and to integrate the data from these various monitoring tools to obtain quantitative estimates of the change in subsurface fluid distributions, pressure changes and associated surface deformation. Monitoring methods being applied include satellite-, surface- and wellbore-based monitoring systems and comprise natural- and controlled-source electromagnetic methods, gravity monitoring, continuous GPS, synthetic aperture radar interferometry (InSAR), tiltmeter array analysis, and chemical tracer studies. Here we focus on the GPS, InSAR and gravity monitoring. Five monitoring sites were installed in 2012 and another six in 2013, each including GPS and InSAR corner reflector monuments (some collocated on the same monument). The continuous GPS data from these stations have been processed on a daily basis in both baseline processing mode using the Bernese GPS Software and precise point positioning mode using CSRS-PPP. Gravity measurements at each site have also been performed in fall 2013, spring 2014 and fall 2015, and at two sites in fall 2014. InSAR measurements of deformation have been obtained for a 5 m footprint at each site as well as at the corner reflector point sources. Here we present the first results of this geodetic deformation monitoring after commencement of CO2 injection on April 14, 2015. The time series of these sites are examined, compared and analyzed with respect to monument stability, seasonal signals, longer term trends, and any changes in motion and mass since CO2 injection.

  5. Results of geophysical monitoring over a "leaking" natural analogue site in Italy

    NARCIS (Netherlands)

    Arts, R.J.; Baradello, L.; Girard, J.F.; Kirby, G.; Lombardi, S.; Williamson, P.; Zaja, A.

    2009-01-01

    CO2 storage in the subsurface is becoming more and more attractive as a means to reduce CO2 emissions to the atmosphere and hence minimize human-induced global warming. The ability to monitor and verify these CO2 storage reservoirs is a key element for further implementation of other storage sites.

  6. Perinatal health monitoring in europe: Results from the EURO-PERISTAT project

    NARCIS (Netherlands)

    Gissler, M.; Mohangoo, A.D.; Blondel, B.; Chalmers, J.; MacFarlane, A.; Gaizauskiene, A.; Gatt, M.; Lack, N.; Sakkeus, L.; Zeitlin, J.

    2010-01-01

    Data about deliveries, births, mothers and newborn babies are collected extensively to monitor the health and care of mothers and babies during pregnancy, delivery and the post-partum period, but there is no common approach in Europe. We analysed the problems related to using the European data for i

  7. LCMS landscape change monitoring system—results from an information needs assessment

    Science.gov (United States)

    Kevin Megown; Brian Schwind; Don Evans; Mark. Finco

    2015-01-01

    Understanding changes in land use and land cover over space and time provides an important means to evaluate complex interactions between human and biophysical systems, to project future conditions, and to design mitigation and adaptive management strategies. Assessing and monitoring landscape change is evolving into a foundational element of climate change adaptation...

  8. The forest health monitoring national technical reports: examples of analyses and results from 2001-2004

    Science.gov (United States)

    Mark J. Ambrose; Barbara L. Conkling; Kurt H. Riitters; John W. Coulston

    2008-01-01

    This brochure presents examples of analyses included in the first four Forest Health Monitoring (FHM) national technical reports. Its purpose is to introduce the reader to the kinds of information available in these and subsequent FHM national technical reports. Indicators presented here include drought, air pollution, forest fragmentation, and tree mortality. These...

  9. Journal Article: EPA's National Dioxin Air Monitoring Network (Ndamn): Design, Implementation, and Final Results

    Science.gov (United States)

    The U.S. Environmental Protection Agency (U.S. EPA) established the National Dioxin Air Monitoring Network (NDAMN) in June of 1998, and operated it until November of 2004. The objective of NDAMN was to determine background air concentrations of polychlorinated dibenzo-p-dioxins (...

  10. Profile grid monitor and first measurement results at the MedAustron accelerator

    CERN Document Server

    Repovz, M; Kerschbaum, A; Osmic, F; Schwarz, S; Burtin, G

    2013-01-01

    MedAustron is a synchrotron based ion beam therapy center located in Wiener Neustadt/Austria. The MedAustron accelerator design is based on CERN’s Proton-Ion Medical Machine Study (PIMMS) [1] and is currently in the accelerator installation and beam commissioning phase. One of the basic measurements for commissioning of an accelerator is also beam profile measurement. The beam at the end of the Low Energy Beam Transport (LEBT) line and in the Medium Energy Beam Transport (MEBT) line (after the fast deflector) is pulsed. Due to pulsed beam the Wire Scanner Monitor (WSX) cannot be used. To measure a beam profile at these locations a new monitor has been developed – Profile Grid Monitor (PGX). The PGX is also known as harp grid monitor and it contains 64 wires positioned vertically and 64 wires horizontally for measuring the beam profile in both transverse planes. The PGX acquires the current of all 128 wires simultaneously, converts it to voltage, digitizes the values and processes the co...

  11. Results of geophysical monitoring over a "leaking" natural analogue site in Italy

    NARCIS (Netherlands)

    Arts, R.J.; Baradello, L.; Girard, J.F.; Kirby, G.; Lombardi, S.; Williamson, P.; Zaja, A.

    2009-01-01

    CO2 storage in the subsurface is becoming more and more attractive as a means to reduce CO2 emissions to the atmosphere and hence minimize human-induced global warming. The ability to monitor and verify these CO2 storage reservoirs is a key element for further implementation of other storage sites.

  12. Monitoring phytoplankton and marine biotoxins in production waters of the Netherlands: results after one decade

    NARCIS (Netherlands)

    Fels-Klerx, van der H.J.; Adamse, P.; Goedhart, P.W.; Poelman, M.; Pol-Hofstad, I.; Egmond, van H.J.; Gerssen, A.

    2012-01-01

    Shellfish products may be contaminated with marine biotoxins which, after consumption, may lead to human illness. The Netherlands has a regular monitoring programme for marine biotoxins and the possible toxic phytoplankton in shellfish production waters. The aim of the current study was to evaluate

  13. Combined sewer overflows in urban areas - interpreting and comparing European CSO monitoring results

    NARCIS (Netherlands)

    Aarts, A.L.F.; Langeveld, J.G.; Ten Veldhuis, J.A.E.; Rietveld, L.C.

    2013-01-01

    Since the initiation of environmental legislation, monitoring campaigns have been done to estimate the characteristic pollutant concentrations of combined sewer overflow water. Such local campaigns are expensive due to the large number of events which should ideally be followed. This study focused o

  14. Perinatal health monitoring in europe: Results from the EURO-PERISTAT project

    NARCIS (Netherlands)

    Gissler, M.; Mohangoo, A.D.; Blondel, B.; Chalmers, J.; MacFarlane, A.; Gaizauskiene, A.; Gatt, M.; Lack, N.; Sakkeus, L.; Zeitlin, J.

    2010-01-01

    Data about deliveries, births, mothers and newborn babies are collected extensively to monitor the health and care of mothers and babies during pregnancy, delivery and the post-partum period, but there is no common approach in Europe. We analysed the problems related to using the European data for i

  15. The use of weekly text messaging over 6 months was a feasible method for monitoring the clinical course of low back pain in patients seeking chiropractic care

    DEFF Research Database (Denmark)

    Axen, I.; Bodin, L.; Bergstrom, G.;

    2012-01-01

    Objective: This study critically evaluates a new method of collecting frequent data using mobile phones and text messages. Fluctuating conditions such as low back pain (LBP) need frequent monitoring to describe the clinical course in detail and to account for individual and subgroup variations. S...

  16. First Results of Continuous GPS Monitoring of Surface Deformation at the Aquistore Underground CO2 Storage Site

    Science.gov (United States)

    Craymer, M. R.; Ferland, R.; Piraszewski, M.; Samsonov, S. V.; Czarnogorska, M.

    2014-12-01

    Aquistore is a demonstration project for the underground storage of CO2 at a depth of ~3350 m near Estevan, Saskatchewan, Canada. An objective of the project is to design, adapt, and test non-seismic monitoring methods that have not been systematically utilized to date for monitoring CO2 storage projects, and to integrate the data from these various monitoring tools to obtain quantitative estimates of the change in subsurface fluid distributions, pressure changes and associated surface deformation. Monitoring methods being applied include satellite-, surface- and wellbore-based monitoring systems and comprise natural- and controlled-source electromagnetic methods, gravity monitoring, GPS, synthetic aperture radar interferometry (InSAR), tiltmeter array analysis, and chemical tracer studies. Here we focus on the GPS monitoring of surface deformation. Five GPS monitoring stations were installed in 2012 and another six in 2013, some collocated on top of InSAR retroreflectors. The GPS data from these stations have been processed on a weekly basis in both baseline processing mode using the Bernese GPS Software and precise point positioning mode using CSRS-PPP. Here we present the first complete results with 1-2 years of data at all sites prior to CO2 injection. The time series of these sites are examined, compared and analysed with respect to monument stability, seasonal signals and estimates of expected regional ground motion. The individual weekly network solutions have also been combined together in a cumulative 4D network solution to provide a preliminary local velocity field in the immediately vicinity of the injection well. These results are also compared to those obtained independently from InSAR, in particular the direct comparison of GPS and InSAR at the retroreflectors.

  17. The Global Ozone Monitoring Experiment (GOME): Mission Concept and First Scientific Results.

    Science.gov (United States)

    Burrows, John P.; Weber, Mark; Buchwitz, Michael; Rozanov, Vladimir; Ladstätter-Weißenmayer, Annette; Richter, Andreas; Debeek, Rüdiger; Hoogen, Ricarda; Bramstedt, Klaus; Eichmann, Kai-Uwe; Eisinger, Michael; Perner, Dieter

    1999-01-01

    The Global Ozone Monitoring Experiment (GOME) is a new instrument aboard the European Space Agency's (ESA) Second European Remote Sensing Satellite (ERS-2), which was launched in April 1995. The main scientific objective of the GOME mission is to determine the global distribution of ozone and several other trace gases, which play an important role in the ozone chemistry of the earth's stratosphere and troposphere. GOME measures the sunlight scattered from the earth's atmosphere and/or reflected by the surface in nadir viewing mode in the spectral region 240-790 nm at a moderate spectral resolution of between 0.2 and 0.4 nm. Using the maximum 960-km across-track swath width, the spatial resolution of a GOME ground pixel is 40 × 320 km2 for the majority of the orbit and global coverage is achieved in three days after 43 orbits.Operational data products of GOME as generated by DLR-DFD, the German Data Processing and Archiving Facility (D-PAF) for GOME, comprise absolute radiometrically calibrated earthshine radiance and solar irradiance spectra (level 1 products) and global distributions of total column amounts of ozone and NO2 (level 2 products), which are derived using the DOAS approach (Differential Optical Absorption Spectroscopy). (Under certain conditions and some restrictions, the operational data products are publically available from the European Space Agency via the ERS Helpdesk.)In addition to the operational data products, GOME has delivered important information about other minor trace gases such as OClO, volcanic SO2, H2CO from biomass burning, and tropospheric BrO. Using an iterative optimal estimation retrieval scheme, ozone vertical profiles can be derived from the inversion of the UV/VIS spectra. This paper reports on the GOME instrument, its operation mode, and the retrieval techniques, the latter with particular emphasis on DOAS (total column retrieval) and advanced optimal estimation (ozone profile retrieval).Observation of ozone depletion in the

  18. The Monitored Atherosclerosis Regression Study (MARS). Design, methods and baseline results.

    Science.gov (United States)

    Cashin-Hemphill, L; Kramsch, D M; Azen, S P; DeMets, D; DeBoer, L W; Hwang, I; Vailas, L; Hirsch, L J; Mack, W J; DeBoer, L

    1992-10-23

    The Monitored Atherosclerosis Regression Study (MARS) was designed to evaluate the effect of cholesterol lowering by monotherapy with an HMG-CoA reductase inhibitor on progression/regression of atherosclerosis in subjects with angiographically documented coronary artery disease. The purpose of this paper is to present the design, methods, and baseline results of MARS. MARS is a prospective, randomized, double-blind, placebo-controlled trial with baseline, 2-year, and 4-year coronary angiography as well as carotid, brachial, and popliteal ultrasonography. Outpatient clinics at the University of Southern California School of Medicine and the University of Wisconsin School of Medicine. Two hundred seventy participants of both sexes were recruited directly from the cardiac catheterization laboratory or by chart review of patients having undergone cardiac catheterization in the past. Subjects were considered eligible if they had angiographically demonstrable atherosclerosis in 2 or more coronary artery segments, unaltered by angioplasty, with at least 1 lesion > or = 50% but or = 500 mg/dL; premenopausal females; uncontrolled hypertension; diabetes mellitus; untreated thyroid disease; liver dysfunction; renal insufficiency; congestive heart failure; major arrhythmia; left ventricular conduction defects; or any life-threatening disease. Subjects were placed on a low-fat, low-cholesterol diet and either 40 mg b.i.d. lovastatin (Mevacor) or placebo. Randomization was stratified by sex, smoking status, and TC. Per-subject average change in %S as determined by quantitative coronary angiography (QCA) is the primary angiographic endpoint. Secondary endpoints are: categorical analyses of the proportion of subjects with progression; human panel reading of coronary angiograms; and change in minimum lumen diameter (MLD) in mm by QCA. Carotid, brachial, and popliteal ultrasonography is also being performed. The subjects randomized into MARS are 91.5% male with an age range of 37 to

  19. Preliminary Results from Real-Time GPS Monitoring in the San Francisco Bay Area

    Science.gov (United States)

    Langbein, J. O.; Guillemot, C.

    2013-12-01

    A web-based monitoring system has been implemented to display displacement estimates in real-time for various combinations of USGS, Plate Boundary Observatory (PBO) and Bay Area Regional Deformation (BARD) network stations in the San Francisco Bay area. Tools and utilities developed in-house are used to visually analyze the quality of estimated positions and gain a better understanding of the challenges involved in integrating displacement data into earthquake early warning (EEW) algorithms. Comparisons of results between differential and precise position estimates obtained from a variety of software packages have led to a closer examination of the epoch-per-epoch latencies, or delays with which those estimates are generated. For example, although position estimates from precise point positioning, with ambiguity resolution, (PPP-AR) computed in real-time are reasonably stable over short-time scales, latencies of 50 seconds or more currently preclude their useful incorporation into EEW algorithms. On the other hand, the latencies for differential position range between less than a second to 10 seconds. The large latencies for PPP-AR are partly due to the fact that displacement estimates obtained from GPS cannot yet be generated at the source but must rely on centralized processing that incorporates instantaneous clock corrections which, in turn must be obtained from external agencies. The latencies, however, are not as critical for the study of post-seismic deformation that occurs minutes to hours following an earthquake. Computation of the power spectra of time series provides a quantitative means to compare the precision of estimated positions that are obtained from various software that process the data in real-time. To first order, the current set of processing algorithms, including those using differential position and PPP-AR, provides nearly equal performance in terms of temporal correlations which is represented by their power spectra. At the shortest periods

  20. Safety and Efficacy of Gadoxetate Disodium–Enhanced Liver MRI in Pediatric Patients Aged >2 Months to <18 Years—Results of a Retrospective, Multicenter Study

    Science.gov (United States)

    Geller, James; Kasahara, Mureo; Martinez, Mercedes; Soresina, Annarosa; Kashanian, Fran; Endrikat, Jan

    2016-01-01

    PURPOSE To assess the safety and efficacy of gadoxetate disodium–enhanced liver MR imaging in pediatric patients. MATERIAL AND METHODS Retrospective, multicenter study including pediatric patients aged >2 months to <18 years who underwent contrast-enhanced liver MRI due to focal liver lesions. A single intravenous bolus injection of 0.025 to 0.05 mmol/kg body weight of gadoxetate disodium was administered. Adverse events (AEs) up to 24 hours after injection were recorded and a one-year follow-up was conducted for all serious and unexpected AEs. Efficacy was defined based on the additional diagnostic information obtained from the combined (pre- and postcontrast) image sets as compared with the precontrast image sets by blinded reading. RESULTS A total of 52 patients for safety and 51 patients for efficacy analyses were evaluated. Twenty-two patients (42.3%) reported a total of 51 serious AEs (SAEs) and one AE after one year. No SAE or AE was related to gadoxetate disodium injection. Gadoxetate disodium–related effects on vital signs were not seen. Additional diagnostic information was obtained for 86.3% of patients. The three most improved efficacy variables were lesion-to-background contrast, lesion characterization, and improved border delineation in 78.4%, 76.5%, and 70.6% of patients, respectively. CONCLUSION Gadoxetate disodium in pediatric patients did not raise any clinically significant safety concern. Contrast enhancement provided additional clinically relevant information. PMID:27478381

  1. Remote monitoring of Xpert® MTB/RIF testing in Mozambique: results of programmatic implementation of GxAlert.

    Science.gov (United States)

    Cowan, J; Michel, C; Manhiça, I; Mutaquiha, C; Monivo, C; Saize, D; Beste, J; Creswell, J; Codlin, A J; Gloyd, S

    2016-03-01

    Electronic diagnostic tests, such as the Xpert® MTB/RIF assay, are being implemented in low- and middle-income countries (LMICs). However, timely information from these tests available via remote monitoring is underutilized. The failure to transmit real-time, actionable data to key individuals such as clinicians, patients, and national monitoring and evaluation teams may negatively impact patient care. To describe recently developed applications that allow for real-time, remote monitoring of Xpert results, and initial implementation of one of these products in central Mozambique. In partnership with the Mozambican National Tuberculosis Program, we compared three different remote monitoring tools for Xpert and selected one, GxAlert, to pilot and evaluate at five public health centers in Mozambique. GxAlert software was successfully installed on all five Xpert computers, and test results are now uploaded daily via a USB internet modem to a secure online database. A password-protected web-based interface allows real-time analysis of test results, and 1200 positive tests for tuberculosis generated 8000 SMS result notifications to key individuals. Remote monitoring of diagnostic platforms is feasible in LMICs. While promising, this effort needs to address issues around patient data ownership, confidentiality, interoperability, unique patient identifiers, and data security.

  2. Assessment of real-world usage of lanreotide AUTOGEL 120 in Polish acromegalic patients - results from the prospective 12-month phase of Lanro-Study.

    Science.gov (United States)

    Orlewska, Ewa; Kos-Kudła, Beata; Sowiński, Jerzy; Sworczak, Krzysztof; Zgliczyński, Wojciech; Andrysiak-Mamos, Elżbieta; Babińska, Anna; Bałdys-Waligórska, Agata; Bandurska-Stankiewicz, Elżbieta; Błaut, Krzysztof; Bolko, Paweł; Foltyn, Wanda; Jakubczyk, Danuta; Jawiarczyk-Przybyłowska, Aleksandra; Junik, Roman; Juraniec, Olga; Lewkowicz, Ewelina; Lewczuk, Anna; Matyjaszek-Matuszek, Beata; Michałek, Krzysztof; Mucha, Sławomir; Orłowska-Florek, Renata; Peszel-Barlik, Marta; Pynka, Sławomir; Rosiek, Violetta; Ruchała, Marek; Rutkowska, Joanna; Słynko-Krzyzostaniak, Julia; Stefańska, Agnieszka; Strzelczyk, Janusz; Syrenicz, Anhelli; Trofimiuk-Müldner, Małgorzata; Waligórska-Stachura, Joanna; Waśko, Ryszard; Witek, Przemysław; Zalewska-Rydzkowska, Danuta; Zdunowski, Piotr; Zemczak, Anna

    2013-01-01

    To assess resource utilization and costs of treatment with lanreotide AUTOGEL 120 mg (ATG120) administered as part of routine acromegaly care in Poland. A multicentre, non-interventional, observational study on resource utilization in Polish acromegalic patients treated with ATG120 at 4 weeks or extended (> 4 weeks) dosing interval. The study recruited adult acromegalic patients treated medically for ≥ 1 year including at least 3 injections of ATG120. Data on dosing interval, aspects of administration, and resource utilization were collected prospectively during 12 months. Costs were calculated in PLN from the public health-care payer perspective for the year 2013. 139 patients were included in the analysis. Changes in dosing regimen were reported in 14 (9.4%) patients. Combined treatment was used in 11 (8%) patients. Seventy patients (50%) received ATG120 at an extended dosing interval; the mean number of days between injections was 35.56 (SD 8.4). ATG120 was predominantly administered in an out-patient setting (77%), by health-care professionals (94%). Mean time needed for preparation and administration was 4.33 and 1.58 min, respectively, mean product wastage - 0.13 mg. Patients were predominantly treated in an out-patient setting with 7.06 physician visits/patient/year. The most common control examinations were magnetic resonance imaging of brain and brain stem (1.36/patient/year), ultrasound of the neck (1.35/patient/year), GH (1.69/patient/year), glycaemia (1.12/patient/year), IGF-1 (0.84/patient/year), pituitary-thyroid axis hormone levels assessment (TSH-0.58/patient/year, T4-0.78/patient/year). There were 0.43 hospitalizations/patient/year. For direct medical costs estimated at PLN 50 692/patient/year the main item was the costs of ATG120 (PLN 4103.87/patient/month; 97%). The mean medical cost, excluding pharmacotherapy, was PLN 1445/patient/year (out-patient care - 49%, hospitalization - 23%, diagnostics/laboratory tests - 28%). These results represent

  3. Changes in skinfold thickness and waist circumference after 12 and 24 months resulting from the NHF-NRG In Balance-project

    National Research Council Canada - National Science Library

    Kwak, Lydia; Kremers, Stef Pj; Candel, Math Jjm; Visscher, Tommy Ls; Brug, Johannes; van Baak, Marleen A

    2010-01-01

    .... Differences between the intervention and control group in changes in body weight, BMI, skinfold thickness and waist circumference at 12 and 24 months were examined using multilevel linear regression...

  4. Machine vision process monitoring on a poultry processing kill line: results from an implementation

    Science.gov (United States)

    Usher, Colin; Britton, Dougl; Daley, Wayne; Stewart, John

    2005-11-01

    Researchers at the Georgia Tech Research Institute designed a vision inspection system for poultry kill line sorting with the potential for process control at various points throughout a processing facility. This system has been successfully operating in a plant for over two and a half years and has been shown to provide multiple benefits. With the introduction of HACCP-Based Inspection Models (HIMP), the opportunity for automated inspection systems to emerge as viable alternatives to human screening is promising. As more plants move to HIMP, these systems have the great potential for augmenting a processing facilities visual inspection process. This will help to maintain a more consistent and potentially higher throughput while helping the plant remain within the HIMP performance standards. In recent years, several vision systems have been designed to analyze the exterior of a chicken and are capable of identifying Food Safety 1 (FS1) type defects under HIMP regulatory specifications. This means that a reliable vision system can be used in a processing facility as a carcass sorter to automatically detect and divert product that is not suitable for further processing. This improves the evisceration line efficiency by creating a smaller set of features that human screeners are required to identify. This can reduce the required number of screeners or allow for faster processing line speeds. In addition to identifying FS1 category defects, the Georgia Tech vision system can also identify multiple "Other Consumer Protection" (OCP) category defects such as skin tears, bruises, broken wings, and cadavers. Monitoring this data in an almost real-time system allows the processing facility to address anomalies as soon as they occur. The Georgia Tech vision system can record minute-by-minute averages of the following defects: Septicemia Toxemia, cadaver, over-scald, bruises, skin tears, and broken wings. In addition to these defects, the system also records the length and

  5. Do developmental milestones at 4, 8, 12 and 24 months predict IQ at 5-6 years old? Results of the EDEN mother-child cohort.

    Science.gov (United States)

    Peyre, Hugo; Charkaluk, Marie-Laure; Forhan, Anne; Heude, Barbara; Ramus, Franck

    2017-03-01

    The present study aims: (i) to determine how well developmental milestones at 4, 8, 12 and 24 months may predict IQ at 5-6 years old, (ii) to identify cognitive domains during the first two years that best predict later IQ and (iii) to determine whether children with IQ in the normal range at 5-6 years old may differ from disabled (IQ  130) with regard to their early cognitive development. The main developmental milestones were collected through self-administered questionnaires rated by parents at 4, 8, 12 and 24 months and through parental questionnaires administered by a trained interviewer and questionnaires completed following a medical examination at 12 months. These questionnaires were derived from the Brunet-Lézine Psychomotor Development Scale and they addressed several cognitive domains (gross and fine motor skills, language and socialization). (i) Developmental milestones predict a substantial part of the later IQ variance from 24 months (R(2) ∼ 20%). (ii) Early language skills more strongly predict later IQ than the other cognitive domains. (iii) Several cognitive domains, but particularly language skills, predict disabled children at 5-6 years old (from the age of 8 months) and gifted children (from the age of 12 months). The present study provides valuable information for early developmental assessment and could contribute to a better understanding of intellectual development. Copyright © 2016 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

  6. Disease-Modifying Drugs Reduce Cortical Lesion Accumulation and Atrophy Progression in Relapsing-Remitting Multiple Sclerosis: Results from a 48-Month Extension Study

    Directory of Open Access Journals (Sweden)

    Francesca Rinaldi

    2015-01-01

    Full Text Available Cortical lesions (CLs and atrophy are pivotal in multiple sclerosis (MS pathology. This study determined the effect of disease modifying drugs (DMDs on CL development and cortical atrophy progression in patients with relapsing-remitting MS (RRMS over 48 months. Patients (n=165 were randomized to sc IFN β-1a 44 μg, im IFN β-1a 30 μg, or glatiramer acetate 20 mg. The reference population comprised 50 DMD-untreated patients with RRMS. After 24 months, 43 of the untreated patients switched to DMDs. The four groups of patients were followed up for an additional 24 months. At 48 months the mean standard deviation number of new CLs was significantly lower in patients treated with sc IFN β-1a (1.4 ± 1.0, range 0–5 compared with im IFN β-1a (2.3 ± 1.3, range 0–6, P=0.004 and glatiramer acetate (2.2 ± 1.5, range 0–7, P=0.03. Significant reductions in CL accumulation and new white matter and gadolinium-enhancing lesions were also observed in the 43 patients who switched to DMDs after 24 months, compared with the 24 months of no treatment. Concluding, this study confirms that DMDs significantly reduce CL development and cortical atrophy progression compared with no treatment.

  7. Older Australians Can Achieve High Adherence to the Mediterranean Diet during a 6 Month Randomised Intervention; Results from the Medley Study.

    Science.gov (United States)

    Davis, Courtney; Hodgson, Jonathan; Bryan, Janet; Garg, Manohar; Woodman, Richard; Murphy, Karen

    2017-05-24

    Adherence to a Mediterranean diet (MedDiet) is thought to be achievable in non-Mediterranean regions, but this has yet to be investigated. We aimed to determine if an older Australian population could adhere to a MedDiet for six months. We conducted a randomised, parallel dietary intervention trial with two dietary arms: the Mediterranean diet (MedDiet) group and the habitual diet (HabDiet) control group. A 15-point Mediterranean diet adherence score and food and nutrient intakes were estimated from three-day weighed food records collected at baseline, two and four months. Erythrocyte fatty acids, serum carotenoids and urinary metabolites were assessed at baseline, three and six months. We enrolled 166 participants; 152 commenced and 137 completed the study (70 in the MedDiet group, 67 in the HabDiet group). Adherence scores were significantly higher in the MedDiet group at two months (between group difference 2.2, 95% CI 1.3, 2.9) and four months (between group difference 2.6, 95% CI 1.9, 3.3). Consumption of vegetables, fruits, fish, legumes, nuts and olive oil significantly increased in the MedDiet group compared to the control, and discretionary food intake decreased (p Mediterranean diet over a six month period.

  8. Impact of eLearning course on nurses' professional competence in seclusion and restraint practices: 9-month follow-up results of a randomized controlled study (ISRCTN32869544).

    Science.gov (United States)

    Kontio, R; Hätönen, H; Joffe, G; Pitkänen, A; Lahti, M; Välimäki, M

    2013-04-01

    eLearning may facilitate continuing vocational education, but data on the long-term effects of an eLearning course are lacking. The aim of this study was to explore the long-term impact of an eLearning course entitled ePsychNurse.Net on psychiatric nurses' professional competence in practicing seclusion and restraint and on their job satisfaction and general self-efficacy at 9-month follow-up. In a randomized controlled study, 12 wards were randomly assigned to the ePsychNurse.Net (intervention) or training as usual (control). Baseline and 9-month follow-up data on nurses' knowledge of coercion-related legislation, physical restraint and seclusion, their attitudes towards physical restraint and seclusion, job satisfaction and general self-efficacy were analysed for 137 completers (those who participated in the 9-month follow-up assessment). No between-group differences were found on any variable, with the exception of a change in attitude to seclusion in favour of the control group. The findings of the long-term effects did not differ from the immediate outcomes (3-month follow-up) and the improved level of knowledge acquired and further consolidation of that knowledge did not take place in the 6-month period after the 3-month ePsychNurse.Net course. The ePsychNurse.Net should be further developed and its future modifications will require additional studies, probably with some new outcome measures.

  9. First results of the research project MIRAMAR, Innovative Methodologies for Coastal Environmental Monitoring and Analysis

    Science.gov (United States)

    Rovere, A.; Casella, E.; Vacchi, M.; Mucerino, L.; Pedroncini, A.; Ferrari, M.; Firpo, M.

    2013-12-01

    A large part of the Mediterranean coastlines are strongly affected by coastal erosion. This is mainly due to human impact, natural hazards and their mutual interaction. All along the Regione Liguria coastlines (Northwestern Mediterranean), significant problems of coastal erosion are reported since the '60s. In this study, we focus on the coastal area between Albenga and Savona, where dramatic coastal retreat of ~2 m y-1 has been inferred from comparison of historic maps and older aerial pictures. Beach monitoring is essential in order to understand the mechanisms of evolution of soft coasts, and the rates of erosion. Traditional beach monitoring techniques involve topographic and bathymetric surveys of the emerged and submerged beach, and/or aerial photos repeated in time and compared through geographical information systems. A major problem of this kind of approach is the high economic cost. This often leads to increase the time lag between successive monitoring campaigns to reduce survey costs, with the consequence of fragmenting the information available for coastal zone management. MIRAMar is a project funded by Regione Liguria through the PO CRO European Social Fund, and it has two main objectives: i) to study and develop an innovative technique, relatively low-cost, to monitor the evolution of the shoreline using low-altitude Unmanned Aerial Vehicle (UAV) photos; ii) to study the impact of different type of storm events on a vulnerable coastal tract subject to coastal erosion using also the data collected by the UAV instrument. To achieve these aims we use a drone with its hardware and software suit, traditional survey techniques (bathymetric surveys, topographic GPS surveys and GIS techniques) and we implement a numerical modeling chain (coupling hydrodynamic, wave and sand transport modules) in order to study the impact of different type of storm events on a vulnerable coastal tract subject to coastal erosion. Aerial picture of one of the beaches studied

  10. Operations of cleanrooms during a forest fire including protocols and monitoring results

    Science.gov (United States)

    Matheson, Bruce A.; Egges, Joanne; Pirkey, Michael S.; Lobmeyer, Lynette D.

    2012-10-01

    Contamination-sensitive space flight hardware is typically built in cleanroom facilities in order to protect the hardware from particle contamination. Forest wildfires near the facilities greatly increase the number of particles and amount of vapors in the ambient outside air. Reasonable questions arise as to whether typical cleanroom facilities can adequately protect the hardware from these adverse environmental conditions. On Monday September 6, 2010 (Labor Day Holiday), a large wildfire ignited near the Boulder, Colorado Campus of Ball Aerospace. The fire was approximately 6 miles from the Boulder City limits. Smoke levels from the fire stayed very high in Boulder for the majority of the week after the fire began. Cleanroom operations were halted temporarily on contamination sensitive hardware, until particulate and non-volatile residue (NVR) sampling could be performed. Immediate monitoring showed little, if any effect on the cleanroom facilities, so programs were allowed to resume work while monitoring continued for several days and beyond in some cases. Little, if any, effect was ever noticed in the monitoring performed.

  11. RAPID: Collaboration Results from Three NASA Centers in Commanding/Monitoring Lunar Assets

    Science.gov (United States)

    Torres, R. Jay; Allan, Mark; Hirsh, Robert; Wallick, Michael N.

    2009-01-01

    Three NASA centers are working together to address the challenge of operating robotic assets in support of human exploration of the Moon. This paper describes the combined work to date of the Ames Research Center (ARC), Jet Propulsion Laboratory (JPL) and Johnson Space Center (JSC) on a common support framework to control and monitor lunar robotic assets. We discuss how we have addressed specific challenges including time-delayed operations, and geographically distributed collaborative monitoring and control, to build an effective architecture for integrating a heterogeneous collection of robotic assets into a common work. We describe the design of the Robot Application Programming Interface Delegate (RAPID) architecture that effectively addresses the problem of interfacing a family of robots including the JSC Chariot, ARC K-10 and JPL ATHLETE rovers. We report on lessons learned from the June 2008 field test in which RAPID was used to monitor and control all of these assets. We conclude by discussing some future directions to extend the RAPID architecture to add further support for NASA's lunar exploration program.

  12. Commissioning experience and first results from the new SLS beam size monitor

    CERN Document Server

    Schlott, V; Saa Hernandez, A; Streun, A; Andersson, A; Breunlin, J; Milas, N

    2013-01-01

    In the context of the TIARA work package “SLS vertical emittance tuning” (SVET), an extremely small vertical beam size of 3.6 $\\mu$m, corresponding to a vertical emittance of 0.9 pm, was verified using an optical monitor based on imaging of $\\pi$-polarized light. Since the existing beam size monitor reached its limit of resolution, a new monitor beam line was designed and installed at the 08BD bending magnet of the Swiss Light Source (SLS) storage ring. Larger magnification and operation at shorter wavelength provide improved spatial resolution. Reflective optics enables convenient switching between different wavelengths. An optical table is located in a hutch outside the storage ring tunnel to provide access during operation. Movable obstacles in the beam path create interference patterns and thus provide redundancy of model based analysis of the images. In this paper we report on our commissioning experience and provide a comparison of the different measurement methods at different wavelengths.

  13. EFFECTS OF 6-MONTHS TREATMENT WITH DONEPEZIL AND RIVASTIGMIN ON RESULTS OF NEUROPSYCHOLOGICAL TESTS OF MMSE, NPI, CLOCK AND BENDER IN PATIENTS WITH ALZHEIMER'S DISEASE

    Directory of Open Access Journals (Sweden)

    R. Abolfazli

    2008-05-01

    Full Text Available Alzheimer's disease is the most common degenerative disease of brain. Nowadays, the most common treatment being used to slow down disease progression, include Donepezil , Rivastigmine and Galantamine, which all of them act as inhibitors of acetyl cholinesterase. General purpose of our study was to show effects of treatment with Donepezil and Rivastigmine, as two drugs that commonly used for treatment of AD in Iran and to compare these effects between two drugs. Samples selected from patients who had Alzheimer` disease with DSM IV criteria and were candidate of receiving Donepezil or Rivastigmine, as treatment of AD, for the first time. We used four neuropsychological tests including MMSE, NPI, Clock and Bender to assess patient's cognitive and behavioral changes during treatment with two drugs. Patients divided to two groups (each group 35 cases; Patients with plan of taking Donepezil entered into one of the groups and patients with plan of taking Rivastigmine entered into another. The four tests were completed once before starting treatment and then, 1 month, 3 months and 6 months after treatment with Donepezil and Rivastigmine. MMSE, 6 months after treatment with Donepezil, improved from 20.63 before treatment to 21.83, which is statistically significant (P = 0.04. Also, MMSE, 6 months after treatment with Rivastigmine, improved from 20.03 before treatment to 22.71, which was statistically significant (P = 0.007. About Clock test, there was a significant improvement from 5.74 before treatment to 6.4 after 6 months of treatment with Rivastigmine; while this significant improvement was not seen in patients receiving Donepezil. In two other tests, no significant differences were seen before and after treatment. Also, No significant difference was detected between two groups and so no different effects on these tests between Donepezil and Rivastigmine in 6 months period of treatment.

  14. Aespoe Hard Rock Laboratory. Prototype Repository. Acoustic emission and ultrasonic monitoring results from deposition hole DA3545G01 in the Prototype Repository between April 2008 and September 2008

    Energy Technology Data Exchange (ETDEWEB)

    Duckworth, D.; Haycox, J.; Pettitt, W.S. (Applied Seismology Consultants, Shrewsbury (United Kingdom))

    2009-03-15

    This report describes results from acoustic emission (AE) and ultrasonic monitoring around a canister deposition hole (DA3545G01) in the Prototype Repository Experiment at SKB's Hard Rock Laboratory (HRL), Sweden. The monitoring aims to examine changes in the rock mass caused by an experimental repository environment, in particular due to thermal stresses induced from canister heating and pore pressures induced from tunnel sealing. Monitoring of this volume has previously been performed during excavation [Pettitt et al., 1999], and during stages of canister heating and tunnel pressurisation [Haycox et al., 2005a and 2005b; Haycox et al., 2006a and 2006b; Zolezzi et al., 2007 and Duckworth et al., 2008]. Further information on this monitoring can be found in Appendix I. This report covers the period between 1st April 2008 and 30th September 2008 and is the seventh instalment of the 6-monthly processing and interpretation of the results from the experiment.

  15. Aespoe Hard Rock Laboratory. Prototype Repository. Acoustic emission and ultrasonic monitoring results from deposition hole DA3545G01 in the Prototype Repository between April 2008 and September 2008

    Energy Technology Data Exchange (ETDEWEB)

    Duckworth, D.; Haycox, J.; Pettitt, W.S. (Applied Seismology Consultants, Shrewsbury (United Kingdom))

    2009-03-15

    This report describes results from acoustic emission (AE) and ultrasonic monitoring around a canister deposition hole (DA3545G01) in the Prototype Repository Experiment at SKB's Hard Rock Laboratory (HRL), Sweden. The monitoring aims to examine changes in the rock mass caused by an experimental repository environment, in particular due to thermal stresses induced from canister heating and pore pressures induced from tunnel sealing. Monitoring of this volume has previously been performed during excavation [Pettitt et al., 1999], and during stages of canister heating and tunnel pressurisation [Haycox et al., 2005a and 2005b; Haycox et al., 2006a and 2006b; Zolezzi et al., 2007 and Duckworth et al., 2008]. Further information on this monitoring can be found in Appendix I. This report covers the period between 1st April 2008 and 30th September 2008 and is the seventh instalment of the 6-monthly processing and interpretation of the results from the experiment.

  16. Soil Moisture Monitoring Using GNSS-R Signals; First Experimental Results with the SAM Sensor

    Science.gov (United States)

    Egido, A.; Martin-Puig, C.; Felip, D.; Garcia, M.; Caparrini, M.; Farres, E.; Ruffini, G.

    2009-04-01

    Observing the Earth surface with Global Navigation Satellite Systems (GNSS) reflected signals has become a noteworthy remote sensing technique for the scientific community. The growing interest in GNSS as a remote sensing tool is due to its global availability and the carrier frequencies used. In fact, L-band, in which all current and next-future Global Navigation Satellite Systems emit, is a portion of the electromagnetic spectrum that highly interacts with the natural medium and for this reason, the possible applications exploiting these signals are numerous. In addition, the large number of GNSS signals in space, and their steadily increasing quantity and quality predicts a promising future for this remote sensing technique. Among a wide variety of applications, soil moisture (SM) monitoring represents an important niche for GNSS-R. SM is a prime parameter for the surface hydrologic cycle since it drives the evapotranspiration and the heat storage capability of the soil, as well as determines the possibility of surface runoff after rainfalls. Despite the recognised environmental and commercial relevance of SM, providing such parameter over global and large scales remains a significant challenge. Sensors based on GNSS-R offer a suitable and efficient solution to this issue. The basis for the retrieval of SM with GNSS-R systems lays in the variability of the ground dielectric properties associated to water content. The higher the concentration of water in the soil, the higher the dielectric constant and reflectivity, which affects signals that reflect from the Earth surface by increasing their peak power. Previous investigations, [1,2] demonstrated the capability of GPS bistatic scatterometers to sense small changes in surface reflectivity, becoming a precedent for this promising research line. GNSS-R present various advantages with respect to others methods currently used to retrieve soil moisture. Firstly, as already mentioned, GNSS signals lie in L band, which

  17. Impact of the Great East Japan Earthquake on feeding methods and newborn growth at 1 month postpartum: results from the Fukushima Health Management Survey

    Energy Technology Data Exchange (ETDEWEB)

    Kyozuka, Hyo; Yasuda, Shun; Kawamura, Makoto; Nomura, Yasuhisa; Fujimori, Keiya [Fukushima Medical University, Department of Obstetrics and Gynecology, School of Medicine, Fukushima (Japan); Goto, Aya; Yasumura, Seiji [Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima (Japan); Fukushima Medical University, Department of Public Health, School of Medicine, Fukushima (Japan); Abe, Masafumi [Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima (Japan)

    2016-05-15

    This study examined the effects of three disasters (the Great East Japan Earthquake of March 11, 2011, followed by a tsunami and the Fukushima Daiichi Nuclear Power Plant accident) on feeding methods and growth in infants born after the disasters. Using results from the Fukushima Health Management Survey, Soso District (the affected area where the damaged nuclear power plant is located) and Aizu District (a less-affected area located farthest from the plant) were compared. In this study, newborn and maternal background characteristics were examined, as well as feeding methods, and other factors for newborn growth at the first postpartum examination for 1706 newborns born after the disaster in the affected (n = 836) and less-affected (n = 870) areas. Postpartum examinations took place 1 month after birth. Feeding method trends were examined, and multivariate regression analyses were used to investigate effects on newborn mass gain. There were no significant differences in background characteristics among newborns in these areas. When birth dates were divided into four periods to assess trends, no significant change in the exclusive breastfeeding rate was found, while the exclusive formula-feeding rate was significantly different across time periods in the affected area (p = 0.02). Multivariate analyses revealed no significant independent associations of maternal depression and change in medical facilities (possible disaster effects) with other newborn growth factors in either area. No area differences in newborn growth at the first postpartum examination or in exclusive breastfeeding rates were found during any period. Exclusive formula-feeding rates varied across time periods in the affected, but not in the less-affected area. It is concluded that effective guidance to promote breast-feeding and prevent exclusive use of formula is important for women in post-disaster circumstances. (orig.)

  18. Activity of chemotherapy in mucinous ovarian cancer with a recurrence free interval of more than 6 months: results from the SOCRATES retrospective study

    Directory of Open Access Journals (Sweden)

    Alletti Desiderio

    2008-09-01

    Full Text Available Abstract Background Mucinous ovarian carcinoma have a poorer prognosis compared with other histological subtypes. The aim of this study was to evaluate, retrospectively, the activity of chemotherapy in patients with platinum sensitive recurrent mucinous ovarian cancer. Methods The SOCRATES study retrospectively assessed the pattern of care of a cohort of patients with recurrent platinum-sensitive ovarian cancer observed in the years 2000–2002 in 37 Italian centres. Data were collected between April and September 2005. Patients with recurrent ovarian cancer with > 6 months of platinum free interval were considered eligible. Results Twenty patients with mucinous histotype and 388 patients with other histotypes were analyzed. At baseline, mucinous tumours differed from the others for an higher number of patients with lower tumor grading (p = 0.0056 and less advanced FIGO stage (p = 0.025. At time of recurrence, a statistically significant difference was found in performance status (worse in mucinous, p = 0.024. About 20% of patients underwent secondary cytoreduction in both groups, but a lower number of patients were optimally debulked in the mucinous group (p = 0.03. Patients with mucinous cancer received more frequently single agent platinum than platinum based-combination therapy or other non-platinum schedules as second line therapy (p = 0.026, with a response rate lower than in non-mucinous group (36.4% vs 62.6%, respectively, p = 0.04. Median time to progression and overall survival were worse for mucinous ovarian cancer. Finally, mucinous cancer received a lower number of chemotherapy lines (p = 0.0023. Conclusion This analysis shows that platinum sensitive mucinous ovarian cancer has a poor response to chemotherapy. Studies dedicated to this histological subgroup are needed.

  19. Developmental Outcomes at 24 Months of Age in Toddlers Supplemented with Arachidonic Acid and Docosahexaenoic Acid: Results of a Double Blind Randomized, Controlled Trial

    Directory of Open Access Journals (Sweden)

    Angela M. Devlin

    2017-09-01

    Full Text Available Little is known about arachidonic acid (ARA and docosahexaenoic acid (DHA requirements in toddlers. A longitudinal, double blind, controlled trial in toddlers (n = 133 age 13.4 ± 0.9 months (mean ± standard deviation, randomized to receive a DHA (200 mg/day and ARA (200 mg/day supplement (supplement or a corn oil supplement (control until age 24 months determined effects on neurodevelopment. We found no effect of the supplement on the Bayley Scales of Infant and Toddler Development 3rd Edition (Bayley-III cognitive and language composites and Beery–Buktenica Developmental Test of Visual–Motor Integration (Beery VMI at age 24 months. Supplemented toddlers had higher RBC phosphatidylcholine (PC, phosphatidylethanolamine (PE, and plasma DHA and ARA compared to placebo toddlers at age 24 months. A positive relationship between RBC PE ARA and Bayley III Cognitive composite (4.55 (0.21–9.00, B (95% CI, p = 0.045 in supplemented boys, but not in control boys, was observed in models adjusted for baseline fatty acid, maternal non-verbal intelligence, and BMI z-score at age 24 months. A similar positive relationship between RBC PE ARA and Bayley III Language composite was observed for supplemented boys (11.52 (5.10–17.94, p < 0.001 and girls (11.19 (4.69–17.68, p = 0.001. These findings suggest that increasing the ARA status in toddlers is associated with better neurodevelopment at age 24 months.

  20. The 24-Month Results of the Lutonix Global SFA Registry: Worldwide Experience With Lutonix Drug-Coated Balloon.

    Science.gov (United States)

    Thieme, Marcus; Von Bilderling, Peter; Paetzel, Christian; Karnabatidis, Dimitrios; Perez Delgado, Julio; Lichtenberg, Michael

    2017-08-28

    The Global SFA Registry sought to assess safety, clinical benefit, and outcomes of the Lutonix 035 drug-coated balloon (DCB) in a heterogeneous, real-world patient population at 12 and 24 months. Numerous clinical studies have evaluated the use of angioplasty for revascularization of femoropopliteal arteries in peripheral arterial disease with restenosis rates of 40% to 60% at 6 to 12 months. Data from recent studies document decreased restenosis rates and improvement in patency in patients receiving angioplasty of femoropopliteal arteries with DCBs. The multicenter, prospective study enrolled 691 patients in 38 centers from 10 countries treated with the Lutonix 035 DCB in femoropopliteal lesions. The primary safety endpoint was freedom from a composite of target vessel restenosis, major index limb amputation, and device- or procedure-related death at 30 days. The primary effectiveness endpoint was freedom from target lesion restenosis at 12 months. Secondary endpoints were acute device and procedural success and clinically assessed primary patency. Freedom at 30 days from the composite safety endpoint was 99.4%. Freedom from target lesion restenosis was 93.4%/89.3% for the overall population, 93.2%/88.2% for long lesions up to 500 mm, and 90.7%/84.6% for in-stent restenosis at 12/24 months. Clinically assessed primary patency by Kaplan-Meier estimates was 85.4%/75.6% at 12/24 months. More than 76% of patients showed improvement of at least 1 Rutherford category. The Global SFA Registry 24-month outcomes confirm the Lutonix 035 DCB is a safe and effective long-term treatment option in real-world patients with peripheral arterial disease with superficial femoral artery lesions, also in long lesions and in-stent restenosis. (Lutonix Global SFA Registry; NCT01864278). Copyright © 2017 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  1. Environmental influences on the spatial ecology of juvenile smalltooth sawfish (Pristis pectinata): results from acoustic monitoring.

    Science.gov (United States)

    Simpfendorfer, Colin A; Yeiser, Beau G; Wiley, Tonya R; Poulakis, Gregg R; Stevens, Philip W; Heupel, Michelle R

    2011-01-01

    To aid recovery efforts of smalltooth sawfish (Pristis pectinata) populations in U.S. waters a research project was developed to assess how changes in environmental conditions within estuarine areas affected the presence, movements, and activity space of this endangered species. Forty juvenile P. pectinata were fitted with acoustic tags and monitored within the lower 27 km of the Caloosahatchee River estuary, Florida, between 2005 and 2007. Sawfish were monitored within the study site from 1 to 473 days, and the number of consecutive days present ranged from 1 to 125. Residency index values for individuals varied considerably, with annual means highest in 2005 (0.95) and lowest in 2007 (0.73) when several P. pectinata moved upriver beyond detection range during drier conditions. Mean daily activity space was 1.42 km of river distance. The distance between 30-minute centers of activity was typically <0.1 km, suggesting limited movement over short time scales. Salinity electivity analysis demonstrated an affinity for salinities between 18 and at least 24 psu, suggesting movements are likely made in part, to remain within this range. Thus, freshwater flow from Lake Okeechobee (and its effect on salinity) affects the location of individuals within the estuary, although it remains unclear whether or not these movements are threatening recovery.

  2. Environmental influences on the spatial ecology of juvenile smalltooth sawfish (Pristis pectinata: results from acoustic monitoring.

    Directory of Open Access Journals (Sweden)

    Colin A Simpfendorfer

    Full Text Available To aid recovery efforts of smalltooth sawfish (Pristis pectinata populations in U.S. waters a research project was developed to assess how changes in environmental conditions within estuarine areas affected the presence, movements, and activity space of this endangered species. Forty juvenile P. pectinata were fitted with acoustic tags and monitored within the lower 27 km of the Caloosahatchee River estuary, Florida, between 2005 and 2007. Sawfish were monitored within the study site from 1 to 473 days, and the number of consecutive days present ranged from 1 to 125. Residency index values for individuals varied considerably, with annual means highest in 2005 (0.95 and lowest in 2007 (0.73 when several P. pectinata moved upriver beyond detection range during drier conditions. Mean daily activity space was 1.42 km of river distance. The distance between 30-minute centers of activity was typically <0.1 km, suggesting limited movement over short time scales. Salinity electivity analysis demonstrated an affinity for salinities between 18 and at least 24 psu, suggesting movements are likely made in part, to remain within this range. Thus, freshwater flow from Lake Okeechobee (and its effect on salinity affects the location of individuals within the estuary, although it remains unclear whether or not these movements are threatening recovery.

  3. RESULTS OF RADIATION-HYGIENIC MONITORING OF THE BASIC PARAMETERS OF THE HUMAN ENVIRONMENT IN THE KIROV REGION

    Directory of Open Access Journals (Sweden)

    B. N. Skolotnev

    2012-01-01

    Full Text Available The paper describes the experience of the laboratory of radiation monitoring in the the Kirov region since 1963. The results of long-term measurements of the environmental objects are presented. Gamma background measurement and investigation of radionuclides’ content in depositions are compared as methods for radioactive contamination assessment.

  4. Monthly 43 GHz VLBA Polarimetric Monitoring of 3C120 over 16 Epochs Evidence for Trailing Shocks in a Relativistic Jet

    CERN Document Server

    Gómez, J L; Alberdi, A; Jorstad, S G; Agudo, I; Gomez, Jose-Luis; Marscher, Alan P.; Alberdi, Antonio; Jorstad, Svetlana G.; Agudo, Ivan

    2001-01-01

    We present a 16-month sequence of monthly polarimetric 43 GHz VLBA images of the radio galaxy 3C 120. The images probe the inner regions of the radio jet of this relatively nearby superluminal radio galaxy at a linear resolution of 0.07 $h_{65}^{-1}$ pc ($H_o= 65 h_{65}$ km s$^{-1}$ Mpc$^{-1}$). We follow the motion of a number of features with apparent velocities between 4.01$\\pm$0.08 and $5.82\\pm 0.13 h_{65}^{-1} c$. A new superluminal knot, moving at $4.29\\pm 0.16 h_{65}^{-1} c$, is observed to be ejected from the core at a time coincident with the largest flare ever observed for this source at millimeter wavelengths. Changes in the position angle of this component, as well as a progressive rotation of its magnetic polarization vector, suggest the presence of a twisted (resembling a helix in projection) configuration of the underlying jet magnetic field and jet geometry. We identify several knots that appear in the wake of the new superluminal component, moving at proper motions $\\sim 4$ times slower than ...

  5. Assessing the Long-Term Effects of EMDR: Results from an 18-Month Follow-Up Study with Adult Female Survivors of CSA

    Science.gov (United States)

    Edmond, Tonya; Rubin, Allen

    2004-01-01

    This 18-month follow-up study builds on the findings of a randomized experimental evaluation that found qualified support for the short-term effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) in reducing trauma symptoms among adult female survivors of childhood sexual abuse (CSA). The current study provides preliminary evidence…

  6. A randomized controlled trial of brain training with non-action video games in older adults: results of the 3-month follow-up.

    Science.gov (United States)

    Ballesteros, Soledad; Mayas, Julia; Prieto, Antonio; Toril, Pilar; Pita, Carmen; Laura, Ponce de León; Reales, José M; Waterworth, John A

    2015-01-01

    This randomized controlled study (ClinicalTrials.gov NCT02007616) investigated the maintenance of training effects of 20 1-hr non-action video game training sessions with selected games from a commercial package on several age-declining cognitive functions and subjective wellbeing after a 3-month no-contact period. Two groups of cognitively normal older adults participated in both the post-training (posttest) and the present follow-up study, the experimental group who received training and the control group who attended several meetings with the research team during the study but did not receive training. Groups were similar at baseline on demographics, vocabulary, global cognition, and depression status. Significant improvements in the trained group, and no variation in the control group had been previously found at posttest, in processing speed, attention and visual recognition memory, as well as in two dimensions of subjective wellbeing. In the current study, improvement from baseline to 3 months follow-up was found only in wellbeing (Affection and Assertivity dimensions) in the trained group whereas there was no change in the control group. Previous significant improvements in processing speed, attention and spatial memory become non-significant after the 3-month interval. Training older adults with non-action video games enhanced aspects of cognition just after training but this effect disappeared after a 3-month no-contact follow-up period. Cognitive plasticity can be induced in older adults by training, but to maintain the benefits periodic boosting sessions would be necessary.

  7. 12-Month comorbidity patterns and associated factors in Europe : results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project

    NARCIS (Netherlands)

    Alonso, J; Angermeyer, M C; Bernert, S; Bruffaerts, R; Brugha, T S; Bryson, H; de Girolamo, G; Graaf, R; Demyttenaere, K; Gasquet, I; Haro, J M; Katz, S J; Kessler, R C; Kovess, V; Lépine, J P; Ormel, J; Polidori, G; Russo, L J; Vilagut, G; Almansa, Josue; Arbabzadeh-Bouchez, S; Autonell, J; Bernal, M; Buist-Bouwman, M A; Codony, M; Domingo-Salvany, A; Ferrer, M; Joo, S S; Martínez-Alonso, M; Matschinger, H; Mazzi, F; Morgan, Z; Morosini, P; Palacín, C; Romera, B; Taub, N; Vollebergh, W A M

    2004-01-01

    Objective: Comorbidity patterns of 12-month mood, anxiety and alcohol disorders and socio-demographic factors associated with comorbidity were studied among the general population of six European countries. Method: Data were derived from the European Study of the Epidemiology of Mental Disorders (ES

  8. Maternal pre-pregnancy body mass index explains infant's weight and BMI at 14 months: results from a multi-ethnic birth cohort study

    NARCIS (Netherlands)

    Mesman, I.; Roseboom, T.J.; Bonsel, G.J.; Gemke, R.J.B.J.; van der Wal, M.F.; Vrijkotte, T.G.

    2009-01-01

    Objective: To investigate the association between (self-reported) maternal pre-pregnancy body mass index (pBMI), and child's weight, height and BMI at age 14 months. Design: Prospective multi-ethnic community-based cohort study. Setting: Amsterdam, The Netherlands. Participants: 8266 pregnant women

  9. Changes in skinfold thickness and waist circumference after 12 and 24 months resulting from the NHF-NRG In Balance-project.

    Science.gov (United States)

    Kwak, Lydia; Kremers, Stef Pj; Candel, Math Jjm; Visscher, Tommy Ls; Brug, Johannes; van Baak, Marleen A

    2010-04-07

    More knowledge is needed regarding the effectiveness of weight gain prevention programmes. The present study tested the 12-and 24-month effectiveness of the 'Netherlands Research programme weight Gain prevention' (NHF-NRG)-In Balance-project, a worksite-based intervention aimed at the prevention of weight gain. Twelve worksites (n = 553 participants) were matched and assigned to either intervention or control group. The worksites and employees of the intervention group received individual (i.e. pedometer, computer-tailored advice) and environmental (i.e. changes in worksite canteen) interventions, directed at physical activity and food intake over 1-year. Differences between the intervention and control group in changes in body weight, BMI, skinfold thickness and waist circumference at 12 and 24 months were examined using multilevel linear regression analyses adjusting for various baseline characteristics (age, gender, BMI, marital status, education and smoking status). A significant greater reduction in skinfold thickness was found in the intervention group than in the control group, both after 12-and 24 months (Unstandardized regression coefficients (B) = -2.52, 95% C.I. -4.58, -0.45; p = 0.018; B = -4.83, 95% C.I. 6.98, -2.67; p skinfold thickness and waist circumference both at 12 and 24 months. It supports the usefulness of worksite-based prevention, especially regarding maintenance of behavioral changes.

  10. A randomized controlled trial of brain training with non-action video games in older adults: Results of the 3-month follow-up

    Directory of Open Access Journals (Sweden)

    Soledad eBallesteros

    2015-04-01

    Full Text Available This randomized controlled study (ClinicalTrials.gov NCT02007616 investigated the maintenance of training effects of 20 1-hr non-action video game training sessions with selected games from a commercial package on several age-declining cognitive functions and subjective wellbeing after a 3-month no-contact period. Two groups of cognitively normal older adults participated in both the post-training (posttest and the present follow-up study, the experimental group who received training and the control group who attended several meetings with the research team during the study but did not receive training. Groups were similar at baseline on demographics, vocabulary, global cognition, and depression status. Significant improvements in the trained group, and no variation in the control group had been previously found at posttest, in processing speed, attention and visual recognition memory, as well as in two dimensions of subjective wellbeing. In the current study, improvement from baseline to 3 months follow-up was found only in wellbeing (Affection and Assertivity dimensions in the trained group whereas there was no change in the control group. Previous significant improvements in processing speed, attention and spatial memory become nonsignificant after the 3-month interval. Training older adults with non-action video games enhanced aspects of cognition just after training but this effect disappeared after a 3-month no-contact follow-up period. Cognitive plasticity can be induced in older adults by training, but to maintain the benefits periodic boosting sessions would be necessary.

  11. Reassuring results on birth outcomes in children fathered by men treated with azathioprine/6-mercaptopurine within 3 months before conception

    DEFF Research Database (Denmark)

    Nørgård, B M; Magnussen, B; Larsen, M D;

    2017-01-01

    OBJECTIVE: Information on the safety of paternal use of azathioprine (AZA) and 6-mercaptopurine (6-MP) prior to conception is limited. Based on nationwide data from the Danish health registries, we examined the association between paternal use of AZA/6-MP within 3 months before conception and adv...

  12. Efficacy and safety of nimesulide long term administration in patients with osteoarthritis: results of 12-months open controlled study DINAMO (long term administration of nimesulide in osteoarthritis multifactor assessment

    Directory of Open Access Journals (Sweden)

    L I Alexeeva

    2009-01-01

    Full Text Available Objective. To compare efficacy and safety of nimesulide and paracetamol in treatment of patients with osteoarthritis (OA during 12 months. Material and methods. 40 women (mean age 66,8±5,1 years with knee osteoarthritis (II-III stage according to Kellgren-Lawrence having intensive pain (>40 mm on VAS were included. Group 1 pts (n=20 received nimesulide 200-100 mg/day. Group 2 pts were treated with paracetamol till 3 g/day. WOMAC was used as efficacy measure. Safety was assessed with endoscopic examination of upper gastrointestinal tract, ECG, blood pressure and ECG Holter monitoring, clinical and biochemical blood parameters. Statistical significance of differences was assessed with Student’s t-test, χ2 and Fisher exact test Results. WOMAC index decreased during treatment from 1182,7±345,9 to 698,4±351,1 for nimesulide and from 1136,4±313,8 to 1031,6±21 for paracetamol (p<0,05. There were 6 cases of gastrointestinal complications and 4 cases of hypertension development or deterioration in each group. Coronary heart disease developed or deteriorated in 4 patients receiving nimesulide but not in control group. Liver function tests did not deteriorated during treatment with nimesulide. Conclusion. Nimesulide was more effective than paracetamol in treatment of OA. But risk of cardiovascular complications development during treatment with NSAIDs requires serious attention. Nimesulide did not induced liver damage during long term treatment.

  13. Hyperactive performance monitoring as a transdiagnostic marker: Results from health anxiety in comparison to obsessive-compulsive disorder.

    Science.gov (United States)

    Riesel, Anja; Goldhahn, Stefanie; Kathmann, Norbert

    2017-02-01

    Hyperactive error-related brain activity has been found in individuals with obsessive-compulsive disorder (OCD), generalized and social anxiety as well as depression and has been proposed as a transdiagnostic marker. The specific phenotype to which it is related is still debated and anxious apprehension, threat sensitivity and checking have been proposed as promising candidates. To validate the idea that hyperactive performance monitoring is shared by anxiety and anxiety-related disorders and to refine our knowledge about its specificity, data from further anxiety and anxiety-related disorders are required. We examined performance monitoring in 24 participants with health anxiety and 24 healthy participants. Further, we compared results to performance monitoring data from 24 patients with OCD taken from a previously published study (Riesel et al., 2014). The three groups were matched with regard to age, gender and level of education. The error-related and correct-related negativity (ERN, CRN) derived during a flanker task served as neural indicators of performance monitoring. Participants with health anxiety showed enhanced ERN amplitudes compared to healthy controls and did not differ from OCD patients in ERN. The Health anxiety and healthy control group did not differ in CRN amplitudes, while OCD patients showed enhanced CRN amplitudes. The results suggest that health anxiety is characterized by hyperactive error-monitoring that seems to represent a common information processing dysfunction in health anxiety and OCD. This validates the idea that hyperactive error-monitoring cuts across diagnoses and seems to be a transdiagnostic trait shared by individuals that are highly sensitive to the commission of errors.

  14. Hyperspectral Monitoring of Green Roof Vegetation Health State in Sub-Mediterranean Climate: Preliminary Results.

    Science.gov (United States)

    Piro, Patrizia; Porti, Michele; Veltri, Simone; Lupo, Emanuela; Moroni, Monica

    2017-03-23

    In urban and industrial environments, the constant increase of impermeable surfaces has produced drastic changes in the natural hydrological cycle. Decreasing green areas not only produce negative effects from a hydrological-hydraulic perspective, but also from an energy point of view, modifying the urban microclimate and generating, as shown in the literature, heat islands in our cities. In this context, green infrastructures may represent an environmental compensation action that can be used to re-equilibrate the hydrological and energy balance and reduce the impact of pollutant load on receiving water bodies. To ensure that a green infrastructure will work properly, vegetated areas have to be continuously monitored to verify their health state. This paper presents a ground spectroscopy monitoring survey of a green roof installed at the University of Calabria fulfilled via the acquisition and analysis of hyperspectral data. This study is part of a larger research project financed by European Structural funds aimed at understanding the influence of green roofs on rainwater management and energy consumption for air conditioning in the Mediterranean area. Reflectance values were acquired with a field-portable spectroradiometer that operates in the range of wavelengths 350-2500 nm. The survey was carried out during the time period November 2014-June 2015 and data were acquired weekly. Climatic, thermo-physical, hydrological and hydraulic quantities were acquired as well and related to spectral data. Broadband and narrowband spectral indices, related to chlorophyll content and to chlorophyll-carotenoid ratio, were computed. The two narrowband indices NDVI705 and SIPI turned out to be the most representative indices to detect the plant health status.

  15. Groundwater monitoring at three Oak Ridge National Laboratory inactive waste impoundments: results after one year

    Energy Technology Data Exchange (ETDEWEB)

    Francis, C. W.; Stansfield, R. G.

    1986-10-01

    To determine if the migration of potential contaminants from three inactive waste impoundments at Oak Ridge National Laboratory poses a threat to groundwater quality, at least one upgradient groundwater monitoring well and threee downgradient monitoring wells were installed at each impoundment in early 1985. These three unlined impoundments, formerly used to collect and, in some instances, treat wastewater are: the 3513 impoundment; the Old Hydrofracture Facility (OHF) impoundment; and the Homogeneous Reactor Experimnt No. 2 impoundment. Groundwater samples were collected quarterly for one year. Analyses were conducted for the groundwater protection parameters promulgated by the Resource Conservation and Recovery Act. The groundwater samples were also analyzed for polychlorinated biphenyls, copper, nickel, zinc, /sup 90/Sr, /sup 137/Cs, and tritium. The contaminants found most often to affect groundwater quality at all three waste impoundments were radionuclides. For example, mean concentrations of gross beta and gross alpha activity exceeded drinking water limits at all three sites. The gross beta limit was exceeded at the 3513 and OHF impoundments by either /sup 90/Sr or tritium levels. At the 3513 impoundment, there was substantial evidence that the downgradient groundwater has been contaminated by chromium and lead and possibly by halogenated organic compounds. At the OHF impoundment, the mean level of tritium measured in the upgradient well (about 91,000 Bq/L as compared with 80,000 Bq/L in the downgradient wells) indicated that the groundwater quality has been affected by the radioactive wastes buried in the low-level radioactive waste burial ground solid waste storage area-5 upgradient of the impoundment. Testing for groundwater contamination, disclosed statistically significant contamination at all three sites.

  16. Clinical usefulness of therapeutic concentration monitoring for imatinib dosage individualization: results from a randomized controlled trial.

    Science.gov (United States)

    Gotta, V; Widmer, N; Decosterd, L A; Chalandon, Y; Heim, D; Gregor, M; Benz, R; Leoncini-Franscini, L; Baerlocher, G M; Duchosal, M A; Csajka, C; Buclin, T

    2014-12-01

    This study assessed whether a cycle of "routine" therapeutic drug monitoring (TDM) for imatinib dosage individualization, targeting an imatinib trough plasma concentration (C min) of 1,000 ng/ml (tolerance: 750-1,500 ng/ml), could improve clinical outcomes in chronic myelogenous leukemia (CML) patients, compared with TDM use only in case of problems ("rescue" TDM). Imatinib concentration monitoring evaluation was a multicenter randomized controlled trial including adult patients in chronic or accelerated phase CML receiving imatinib since less than 5 years. Patients were allocated 1:1 to "routine TDM" or "rescue TDM." The primary endpoint was a combined outcome (failure- and toxicity-free survival with continuation on imatinib) over 1-year follow-up, analyzed in intention-to-treat (ISRCTN31181395). Among 56 patients (55 evaluable), 14/27 (52 %) receiving "routine TDM" remained event-free versus 16/28 (57 %) "rescue TDM" controls (P = 0.69). In the "routine TDM" arm, dosage recommendations were correctly adopted in 14 patients (median C min: 895 ng/ml), who had fewer unfavorable events (28 %) than the 13 not receiving the advised dosage (77 %; P = 0.03; median C min: 648 ng/ml). This first target concentration intervention trial could not formally demonstrate a benefit of "routine TDM" because of small patient number and surprisingly limited prescriber's adherence to dosage recommendations. Favorable outcomes were, however, found in patients actually elected for target dosing. This study thus shows first prospective indication for TDM being a useful tool to guide drug dosage and shift decisions. The study design and analysis provide an interesting paradigm for future randomized TDM trials on targeted anticancer agents.

  17. A Catalog of Terrestrial Gamma-Ray Flashes Observed with the Fermi- Gamma-Ray Burst Monitor: The First Sixteen Months of Operation

    Science.gov (United States)

    Fishman, Gerald J.; Briggs, M. S.; Connaughton, V.; Bhat, P. N.

    2009-01-01

    The Gamma-ray Burst Monitor (GBM) on the Fermi Gamma-ray Space Telescope Observatory (Fermi) has been detecting on the average about one terrestrial gamma-ray flash every four weeks. This catalog presents the basic characteristics of observed TGFs from the beginning of the Fermi-GBM operation in 2008 July until 2009 October. The thick bismuth germanate (BGO) scintillation detectors of the GBM system have observed photon energies from TGFs at energies above 30 MeV. It is found that the TGF pulses are typically shorter than previously reported, and in several cases less than 0.2ms. Extremely high counting rates are encountered 200kcps or higher per detector during portions of some TGFs. These high rates require considerable corrections (with inherent assumptions) to the observed data in order to derive the true counting rates.

  18. Monitoring of PAHs and alkylated PAHs in aquatic organisms after 1 month from the Solar I oil spill off the coast of Guimaras Island, Philippines.

    Science.gov (United States)

    Uno, Seiichi; Koyama, Jiro; Kokushi, Emiko; Monteclaro, Harold; Santander, Sheryll; Cheikyula, J Orkuma; Miki, Shizuho; Añasco, Nathaniel; Pahila, Ida G; Taberna, Hilario S; Matsuoka, Tatsuro

    2010-06-01

    Following the oil spill accident of the Solar I tanker in 2006 off the coast of Guimaras Island in the Philippines, polycyclic aromatic hydrocarbons (PAHs) and alkylated PAHs in some aquatic organisms were investigated at Luzaran in Guimaras and Taklong Islands, which were heavily polluted with spilled oil, immediately and 1 month after the accident. The concentrations of total PAHs were 11.9-52.3 ng/g dry weight in fish. Meanwhile, total PAH concentrations in shellfish were 38.0-3,102 ng/g dry weight in Luzaran and 128-236 ng/g dry weight in Taklong. Pyrene, phenanthrene, and fluoranthene were dominant in most fish and chrysene in all shellfish. Significantly higher concentrations of all alkylated homologs were detected in shellfish than in fish. These differences had two possible causes, that is, the differences between fish and shellfish could be attributed to the uptake routes and/or their metabolizing abilities.

  19. Ultrafine particles in four European urban environments: Results from a new continuous long-term monitoring network

    Science.gov (United States)

    Hofman, J.; Staelens, J.; Cordell, R.; Stroobants, C.; Zikova, N.; Hama, S. M. L.; Wyche, K. P.; Kos, G. P. A.; Van Der Zee, S.; Smallbone, K. L.; Weijers, E. P.; Monks, P. S.; Roekens, E.

    2016-07-01

    To gain a better understanding on the spatiotemporal variation of ultrafine particles (UFPs) in urban environments, this study reports on the first results of a long-term UFP monitoring network, set up in Amsterdam (NL), Antwerp (BE), Leicester (UK) and London (UK). Total number concentrations and size distributions were assessed during 1-2 years at four fixed urban background sites, supplemented with mobile trailer measurements for co-location monitoring and additional short-term monitoring sites. Intra- and interurban spatiotemporal UFP variation, associations with commonly-monitored pollutants (PM, NOx and BC) and impacts of wind fields were evaluated. Although comparable size distributions were observed between the four cities, source-related differences were demonstrated within specific particle size classes. Total and size-resolved particle number concentrations showed clear traffic-related temporal variation, confirming road traffic as the major UFP contributor in urban environments. New particle formation events were observed in all cities. Correlations with typical traffic-related pollutants (BC and NOx) were obtained for all monitoring stations, except for Amsterdam, which might be attributable to UFP emissions from Schiphol airport. The temporal variation in particle number concentration correlated fairly weakly between the four cities (rs = 0.28-0.50, COD = 0.28-0.37), yet improved significantly inside individual cities (rs = 0.59-0.77). Nevertheless, considerable differences were still obtained in terms of particle numbers (20-38% for total particle numbers and up to 49% for size-resolved particle numbers), confirming the importance of local source contributions and the need for careful consideration when allocating UFP monitoring stations in heterogeneous urban environments.

  20. Results from a 12 months, randomized, clinical trial comparing an olmesartan/amlodipine single pill combination to olmesartan and amlodipine monotherapies on blood pressure and inflammation.

    Science.gov (United States)

    Derosa, Giuseppe; Cicero, Arrigo F G; Carbone, Anna; Querci, Fabrizio; Fogari, Elena; D'Angelo, Angela; Maffioli, Pamela

    2014-01-23

    Hypertension affects nearly 1 in 3 adults in the United States, and it is an important modifiable risk factor for coronary artery disease, heart failure, renal failure, and stroke. The aim of this study was to evaluate the effects of a fixed-dose olmesartan/amlodipine combination on blood pressure control, lipid profile, insulin sensitivity, and inflammation compared to singles monotherapies. We randomized 276 hypertensive patients to olmesartan 20 mg, amlodipine 10mg or a single pill containing a fixed-dose olmesartan/amlodipine combination 20/5mg for 12 months. We evaluated: body weight, body mass index (BMI), systolic and diastolic blood pressure (SBP and DBP), fasting plasma glucose (FPG), fasting plasma insulin (FPI), lipid profile, omentin, chemerin, high sensitivity C-reactive protein (Hs-CRP). At baseline, and after 6 and 12 months, patients underwent an euglycemic, hyperinsulinemic clamp to assess insulin sensitivity (M value). Olmesartan/amlodipine combination was more effective than amlodipine or olmesartan in reducing blood pressure. Olmesartan/amlodipine combination, but not amlodipine, decreased FPG after 12 months. Olmesartan/amlodipine combination better decreased FPI and HOMA index and increased M value compared to olmesartan and amlodipine monotherapies. Olmesartan/amlodipine significantly decreased chemerin and omentin compared to olmesartan and amlodipine. Other than to be more effective in reducing blood pressure, olmesartan/amlodipine single pill combination gave also a major increase of insulin sensitivity and a decrease of inflammatory markers compared to single monotherapies. Copyright © 2013 Elsevier B.V. All rights reserved.

  1. Effect of palmitoylethanolamide on visual field damage progression in normal tension glaucoma patients: results of an open-label six-month follow-up.

    Science.gov (United States)

    Costagliola, Ciro; Romano, Mario R; dell'Omo, Roberto; Russo, Andrea; Mastropasqua, Rodolfo; Semeraro, Francesco

    2014-09-01

    The purpose of this study is to assess the effect of palmitoylethanolamide (PEA) oral administration on intraocular pressure (IOP) and visual field damage progression in normal-tension glaucoma (NTG) patients. Thirty-two consecutive patients affected by NTG were enrolled and randomized in a 1:1 ratio to receive PEA treatment (group A) or no treatment (group B). Group A patients took ultramicronized 300 mg PEA tablets two times per day for six months. Best-corrected visual acuity (BCVA), IOP, and visual field test were evaluated at baseline and at the end of the six-month follow-up. No significant differences in clinical parameters between the two groups were observed at baseline. At six months, group A patients showed significant IOP reduction (from 14.4±3.2 mm Hg to 11.1±4.3 mm Hg, pVisual field parameters significantly diminished in patients receiving PEA compared to baseline values (-7.65±6.55 dB vs. -4.55±5.31 dB, pvisual field indices in individuals affected by NTG. Neither ocular nor systemic side effects were recorded during the study period.

  2. Evaluation of Commercial Self-Monitoring Devices for Clinical Purposes: Results from the Future Patient Trial, Phase I

    Directory of Open Access Journals (Sweden)

    Soren Leth

    2017-01-01

    Full Text Available Commercial self-monitoring devices are becoming increasingly popular, and over the last decade, the use of self-monitoring technology has spread widely in both consumer and medical markets. The purpose of this study was to evaluate five commercially available self-monitoring devices for further testing in clinical applications. Four activity trackers and one sleep tracker were evaluated based on step count validity and heart rate validity. Methods: The study enrolled 22 healthy volunteers in a walking test. Volunteers walked a 100 m track at 2 km/h and 3.5 km/h. Steps were measured by four activity trackers and compared to gyroscope readings. Two trackers were also tested on nine subjects by comparing pulse readings to Holter monitoring. Results: The lowest average systematic error in the walking tests was −0.2%, recorded on the Garmin Vivofit 2 at 3.5 km/h; the highest error was the Fitbit Charge HR at 2 km/h with an error margin of 26.8%. Comparisons of pulse measurements from the Fitbit Charge HR revealed a margin error of −3.42% ± 7.99% compared to the electrocardiogram. The Beddit sleep tracker measured a systematic error of −3.27% ± 4.60%. Conclusion: The measured results revealed the current functionality and limitations of the five self-tracking devices, and point towards a need for future research in this area.

  3. Evaluation of Commercial Self-Monitoring Devices for Clinical Purposes: Results from the Future Patient Trial, Phase I

    Science.gov (United States)

    Leth, Soren; Hansen, John; Nielsen, Olav W.; Dinesen, Birthe

    2017-01-01

    Commercial self-monitoring devices are becoming increasingly popular, and over the last decade, the use of self-monitoring technology has spread widely in both consumer and medical markets. The purpose of this study was to evaluate five commercially available self-monitoring devices for further testing in clinical applications. Four activity trackers and one sleep tracker were evaluated based on step count validity and heart rate validity. Methods: The study enrolled 22 healthy volunteers in a walking test. Volunteers walked a 100 m track at 2 km/h and 3.5 km/h. Steps were measured by four activity trackers and compared to gyroscope readings. Two trackers were also tested on nine subjects by comparing pulse readings to Holter monitoring. Results: The lowest average systematic error in the walking tests was −0.2%, recorded on the Garmin Vivofit 2 at 3.5 km/h; the highest error was the Fitbit Charge HR at 2 km/h with an error margin of 26.8%. Comparisons of pulse measurements from the Fitbit Charge HR revealed a margin error of −3.42% ± 7.99% compared to the electrocardiogram. The Beddit sleep tracker measured a systematic error of −3.27% ± 4.60%. Conclusion: The measured results revealed the current functionality and limitations of the five self-tracking devices, and point towards a need for future research in this area. PMID:28117736

  4. Applications of Hobbyist Electronics in Monitoring Stemflow Processes: Preliminary Insights and Results

    Science.gov (United States)

    Carlyle-Moses, D. E.; Turner, B.; Hill, D. J.

    2016-12-01

    Leveraging the power and adaptability of inexpensive, accessible hobbyist electronics it has been possible to gain insights into the processes governing stemflow. The sensor platform utilizes an Arduino® microcontroller equipped with an ultrasonic sensor and wetness sensor as well as a GPS unit for accurate timestamps. The wetness sensor, which is attached to the terminus of a collection tube diverting water entering the stemflow collar to a collection vessel, provides the precise time in which stemflow commences. In turn, this time can be compared with the time stamp record of a high precision tipping-bucket rain gauge so that the rain depth required for stemflow generation can be derived. In addition, the ultrasonic sensor mounted above the stemflow collection vessel monitors changes in water depth over time. The changes in water depth are then converted to volumetric changes allowing for reasonable approximations of stemflow flow rates throughout the storm event. As a trial, the stemflow monitoring platform was deployed from May 1 to June 30, 2016 on an ornamental Green Ash (Fraxinus pennsylvanica Marsh.) tree on the grounds of Thompson Rivers University in Kamloops, British Columbia, Canada (500 40' 25" N, 1200 21' 50" W). The tree was in full-leaf condition, was 7.4 m in height and had a diameter at breast height of 10.8 cm. Rain totaled 77.2 mm during the study and was distributed over 15 events (mean = 5.1 mm, range = 0.2 - 14.3 mm), with the five smallest rain events (0.2 - 1.3 mm) not producing stemflow. The study period funneling ratio was 14.0 (event range = 0.0 - 40.0). Regression analysis revealed that for events in which stemflow was produced, rainfall depth explained only 50.2 percent of the variation in event stemflow volumes. The variant nature of stemflow in our study was a consequence of both highly variable mean event flow rates once stemflow had commenced (mean = 0.197 L / mm of rain, coefficient of variation = 0.67, range = 0.009 - 0.444 L

  5. Safety and efficacy trial of adipose-tissue derived oral preparation V-6 Immunitor (V-6: results of open-label, two-month, follow-up study

    Directory of Open Access Journals (Sweden)

    Jirathitikal Vichai

    2010-02-01

    Full Text Available Abstract Background Chronic inflammations, atherosclerosis and obesity, are major risk factors for cardiovascular diseases. Immune modulation of the inflammatory response has shown promise in animal models of atherogenesis and metabolic disease. Tableted dietary supplement, V-6, containing pooled antigens derived from pig adipose tissue has been administered daily to 12 volunteers for 2 months. Results No significant changes were observed in liver ALT and AST enzymes, i.e., 28 vs 23.8 IU and 22.6 vs 24.8 IU, with p = 0.07 and p = 0.49, respectively. Creatinine decreased; 0.88 vs 0.84 mg/dL (p = 0.05 while BUN moved upward; 14.5 vs 17.5 mg/dL (p = 0.01, but both values remained within normal range. Blood glucose remained within normal range; 96.1 vs 101.1 mg/dL (p = 0.04. Complete blood cell analysis has not revealed any change except slight increase in hemoglobin; 13.13 to 13.96 g/dL (p = 0.0002; hematocrit and red blood cells count 40.3 to 42.3% (p = 0.02 and 5.15 to 5.35 × 106 cells/mm3 (p = 0.03 respectively. Blood pressure systolic and diastolic values were not affected, i.e., 116.1 vs 116.3 (p = 0.12 and 76.8 vs 76.6 (p = 0.99. Body weight and body mass index (BMI remained same; 66.4 vs 66.3 kg (p = 0.47 and 25.7 vs 25.6 kg/m2 (p = 0.2. Body fat deposit indices, such as abdomen; mid-arm; and thigh circumferences declined by 3.5 cm (p = 0.008; 1.2 cm (p = 0.004; and 3.0 cm (p = 0.0007 respectively. The total cholesterol and LDL levels did not change; 195.5 vs 195.1 (-0.2%; p = 0.8 and 113.4 vs 120.3 (6.1%; p = 0.08 respectively. Triglycerides have been reduced but not statistically significant; 168.1 vs 118 mg/dL (-29.8%; p = 0.2. In contrast, HDL content had risen by 29.7% from 39.4 to 51.1 mg/dL in all 12 patients (p = 0.000003. TG/HDL ratio - a marker of insulin resistance - was reduced from 4.78 to 2.56 (-46.5%; p = 0.04. Conclusions These results demonstrate that V-6 is safe and has a potential as an anti-atherogenic and overweight

  6. Results of monitoring of the high orbits with ISON optical network

    Science.gov (United States)

    Molotov, Igor; Schildknecht, Thomas; Zalles, Rodolfo; Rumyantsev, Vasilij; Voropaev, Viktor; Zolotov, Vladimir; Kokina, Tatiana; Montojo, Francisco Javier; Namkhai, Tungalag

    2016-07-01

    International Scientific Optical Network (ISON) represents one of largest systems specializing in observation of space objects. ISON provides permanent monitoring of the whole GEO region, regular surveying of Molniya type orbits, and tracking of objects at GEO, GTO, HEO and LEO. ISON project is continuously developing and is joining now the 37 observation facilities in 15 countries with 79 telescopes of different class (aperture from 12.5 cm to 2.6 m). 15.4 millions measurements in 2.1 millions of tracklets for about 4100 objects are collected by KIAM in 2015. 339 new space objects have been discovered, 307 previously lost objects have been rediscovered. Telescopes of two European observatories (AIUB Zimmerwald and TFRM Barcelona) and two Latin American observatories (Bolivian Tarija and Mexican UAS Cosala) have joined to the ISON survey subsystem. New subsystem of 7 telescopes for extended GEO surveys is created (it allows KIAM to determine more precise GEO orbits for conjunction analysis). Also deployment of Roscosmos subsystem of six dedicated mini-observatories EOP-1/EOP-2 has been completed. ISON encompasses five groups of telescopes and three scheduling centers to better serve user's requests. Obtained measurements are processing at KIAM ballistic center to be used for scientific and applied goals, including collision risks analysis and space situation analysis. Achieved parameters of the above mentioned telescopes and plans of ISON network development will be presented and discussed.

  7. Monitoring of fluvial transport in small upland catchments - methods and preliminary results

    Science.gov (United States)

    Janicki, Grzegorz; Rodzik, Jan; Chabudziński, Łukasz; Franczak, Łukasz; Siłuch, Marcin; Stępniewski, Krzysztof; Dyer, Jamie L.; Kołodziej, Grzegorz; Maciejewska, Ewa

    2014-06-01

    In April 2011 a study was initiated, financed from resources of the Polish National Science Centre, entitled: ‘Rainstorm prediction and mathematic modelling of their environmental and social-economical effects’ (No. NN/306571640). The study, implemented by a Polish-American team, covers meteorological research, including: (1) monitoring of single cell storms developing in various synoptic situations, (2) detection of their movement courses, and (3) estimation of parameters of their rain field. Empirical studies, including hydrological and geomorphological measurements, are conducted in objects researched thoroughly in physiographic terms (experimental catchments) in the Lublin region (SE Poland), distinguished by high frequency of occurrence of the events described. For comparative purposes, studies are also carried out on selected model areas in the lower course of the Mississippi River valley (USA), in a region with high frequency of summer rainstorms. For detailed studies on sediment transport processes during rainstorm events, catchments of low hydrological rank and their sub-catchments in a cascade system were selected. For the basic, relatively uniform geomorpho logical units distinguished this way, erosion and deposition balance of material transported was determined. The aim of work was to determine influence of weather condition on fluvial transport rate in small catchment with low hydrological order

  8. Operational evaluation of the Mediterranean Monitoring and Forecasting Centre products: implementation and results

    Science.gov (United States)

    Tonani, M.; Nilsson, J. A. U.; Lyubartsev, V.; Grandi, A.; Aydogdu, A.; Azzopardi, J.; Bolzon, G.; Bruschi, A.; Drago, A.; Garau, T.; Gatti, J.; Gertman, I.; Goldman, R.; Hayes, D.; Korres, G.; Lorente, P.; Malacic, V.; Mantziafou, A.; Nardone, G.; Olita, A.; Ozsoy, E.; Pairaud, I.; Pensieri, S.; Perivoliotis, L.; Petelin, B.; Ravaioli, M.; Renault, L.; Sofianos, S.; Sotillo, M. G.; Teruzzi, A.; Zodiatis, G.

    2012-04-01

    A web-based validation platform has been developed at the Istituto Nazionale di Geofisica e Vulcanologia (INGV) for the Near Real Time validation of the MyOcean-Mediterranean Monitoring and Forecasting Centre products (Med-MFC). A network for the collection of the in-situ observations, the nested sub-basin forecasting systems model data (provided by the partners of the Mediterranean Operational Oceanography Network, MOON) and the Sea Surface Temperature (SST) satellite data has been developed and is updated every day with the new available data. The network collects temperature, salinity, currents and sea level data. The validation of the biogeochemical forecast products is done by use of ocean colour satellite data produced for the Mediterranean Sea. All the data are organized in an ad hoc database interfaced with a dedicated software which allows interactive visualizations and statistics (CalVal SW). This tool allows to evaluate NRT products by comparison with independent observations for the first time. The heterogeneous distribution and the scarcity of moored observations reflect with large areas uncovered with measurements. Nevertheless, the evaluation of the forecast at the locations of observations could be very useful to discover sub-regions where the model performances can be improved, thus yielding an important complement to the basin-mean statistics regularly calculated for the Mediterranean MFC products using semi-independent observations.

  9. Results of the of wintering bird populations monitoring in the region of Nizhnee Prisurye

    Directory of Open Access Journals (Sweden)

    Ekaterina S. Preobrazhenskaya

    2016-05-01

    Full Text Available The monitoring of wintering bird populations in the region of Nizhnee Prisurie on the territory of Chuvash Republic was carried out in 1989–1990. From 2000 censuses were conducted on the territory of the nature reserve "Prisurskiy" and the National Park "Chavash Varmane". These regular censuses were called project "Parus" by the Menzbir Ornithological Society of the Russian Academy of Sciences. The last ten years they were also included in the overall-Russian campaign "Euro-Asian Christmas Bird Counts" project from the Russian Birds Conservation Union. During these 20 years there were 44 bird species registered in the studied area. Eleven of them are marked by single or rare. Four species - Regulus regulus, Aegithalos caudatus, Spinus spinus and Carduelis carduelis – increased their abundance from 1990 till the middle 2000-s and then – decreased. Dendrocopos minor showed the opposite trend. The abundance of 13 species in the 1990-s was higher, sometimes significantly, than in the 2000s and 2010s. The reason may be searched in the differences between the censuses areas in 1990s and 2000s. However, the decreasing of the population densities is typical for other forest species, not only in Nizhnee Prisurie, but also in other model territories. In general, during the last 25 years we can see negative trends in the population dynamics of wintering bird species within the East European plain.

  10. Efficacy of intradermal mesotherapy in cellulite reduction - Conventional and high-frequency ultrasound monitoring results.

    Science.gov (United States)

    Sylwia, Malinowska; Krzysztof, Mlosek Robert

    2017-10-01

    Cellulite affects the majority of women and is an unacceptable cosmetic defect. Therefore, effective methods for cellulite reduction are being sought. Intradermal mesotherapy is one of such methods. The aim of the study was to assess the efficacy of intradermal mesotherapy in cellulite reduction, using conventional and high-frequency ultrasound. Twenty-one women with cellulite underwent a series of intradermal mesotherapy procedures. The following parameters were assessed: thickness of epidermis, dermis and hypodermis, echogenicity of dermis and the surface area of serrated hypodermis-dermis junction. Furthermore, the thigh circumference was measured; body mass index and cellulite severity were assessed based on photographs using Nürnberger-Müller's scale. Intradermal mesotherapy reduced severity of cellulite. The surface area of serrated hypodermis-dermis junction and hypodermis thickness decreased significantly as compared to baseline. Cellulite reduction was also confirmed by palpation, decreased thigh circumference and the Nürnberger-Müller's grade. There were no statistically significant changes in epidermis or dermis thickness, body weight and the BMI. Intradermal mesotherapy offers effective cellulite reduction. It is a simple and safe treatment, which makes it popular. Further research in mesotherapy is essential due to a limited number of published studies. Ultrasound is a useful method to monitor intradermal mesotherapy and assess its efficacy.

  11. Ovčiarsko tunnel – interpretation of the results of the geotechnical monitoring

    Science.gov (United States)

    Ondráček, Jakub

    2017-09-01

    The Ovčiarsko twin-tube tunnel is part of the development of the Hričovské Podhradie – Lietavská Lúčka section of the D1 motorway, running southwest of the Žilina town. The D1 motorway overcomes the detached mass of an overthrust sheet and the western adge of the Paleogene fill of the Žilina Basin through the Ovčiarsko tunnel. The 2T – 8 category is designated for the Ovčiarsko tunnel with the total length of the northern tunnel tube 2360 m and southern tunnel tube 2367 m. the tunnel orientation to the cardinals is on the west-east axis, the marking of tunnel portals and tunnels tubes is distinguished according to it. The design speed is 100 km/h, respectively 90 km/h under worsened weather conditions. Parts of the tunnel are three cross passages passable for vehicles and five cross passages passable for pedestrians, serving as protected escape routes. This report describes geotechnical monitoring, construction technology and procedures with respect to complicated geological conditions. The geological conditions require the operative approach of the project owner, contractor, designer and geologist to the optimum solution for the running of the tunnel construction.

  12. Methods for Minimization and Management of Variability in Long-Term Groundwater Monitoring Results

    Science.gov (United States)

    2015-12-01

    statistical analyses. A balanced dataset based on analytical results for each planned primary sample: 480 total samples Two demonstration sites... balanced dataset of analytical results from 480 groundwater samples based on analytical results for each planned primary sample: two demonstration...the peer review analyst of the staff chemist , the department supervisor, and finally the data entry personnel. The laboratory report will be

  13. The Status of Honey Bee Health in Italy: Results from the Nationwide Bee Monitoring Network.

    Science.gov (United States)

    Porrini, Claudio; Mutinelli, Franco; Bortolotti, Laura; Granato, Anna; Laurenson, Lynn; Roberts, Katherine; Gallina, Albino; Silvester, Nicholas; Medrzycki, Piotr; Renzi, Teresa; Sgolastra, Fabio; Lodesani, Marco

    2016-01-01

    In Italy a nation-wide monitoring network was established in 2009 in response to significant honey bee colony mortality reported during 2008. The network comprised of approximately 100 apiaries located across Italy. Colonies were sampled four times per year, in order to assess the health status and to collect samples for pathogen, chemical and pollen analyses. The prevalence of Nosema ceranae ranged, on average, from 47-69% in 2009 and from 30-60% in 2010, with strong seasonal variation. Virus prevalence was higher in 2010 than in 2009. The most widespread viruses were BQCV, DWV and SBV. The most frequent pesticides in all hive contents were organophosphates and pyrethroids such as coumaphos and tau-fluvalinate. Beeswax was the most frequently contaminated hive product, with 40% of samples positive and 13% having multiple residues, while 27% of bee-bread and 12% of honey bee samples were contaminated. Colony losses in 2009/10 were on average 19%, with no major differences between regions of Italy. In 2009, the presence of DWV in autumn was positively correlated with colony losses. Similarly, hive mortality was higher in BQCV infected colonies in the first and second visits of the year. In 2010, colony losses were significantly related to the presence of pesticides in honey bees during the second sampling period. Honey bee exposure to poisons in spring could have a negative impact at the colony level, contributing to increase colony mortality during the beekeeping season. In both 2009 and 2010, colony mortality rates were positively related to the percentage of agricultural land surrounding apiaries, supporting the importance of land use for honey bee health.

  14. The Status of Honey Bee Health in Italy: Results from the Nationwide Bee Monitoring Network.

    Directory of Open Access Journals (Sweden)

    Claudio Porrini

    Full Text Available In Italy a nation-wide monitoring network was established in 2009 in response to significant honey bee colony mortality reported during 2008. The network comprised of approximately 100 apiaries located across Italy. Colonies were sampled four times per year, in order to assess the health status and to collect samples for pathogen, chemical and pollen analyses. The prevalence of Nosema ceranae ranged, on average, from 47-69% in 2009 and from 30-60% in 2010, with strong seasonal variation. Virus prevalence was higher in 2010 than in 2009. The most widespread viruses were BQCV, DWV and SBV. The most frequent pesticides in all hive contents were organophosphates and pyrethroids such as coumaphos and tau-fluvalinate. Beeswax was the most frequently contaminated hive product, with 40% of samples positive and 13% having multiple residues, while 27% of bee-bread and 12% of honey bee samples were contaminated. Colony losses in 2009/10 were on average 19%, with no major differences between regions of Italy. In 2009, the presence of DWV in autumn was positively correlated with colony losses. Similarly, hive mortality was higher in BQCV infected colonies in the first and second visits of the year. In 2010, colony losses were significantly related to the presence of pesticides in honey bees during the second sampling period. Honey bee exposure to poisons in spring could have a negative impact at the colony level, contributing to increase colony mortality during the beekeeping season. In both 2009 and 2010, colony mortality rates were positively related to the percentage of agricultural land surrounding apiaries, supporting the importance of land use for honey bee health.

  15. The Status of Honey Bee Health in Italy: Results from the Nationwide Bee Monitoring Network

    Science.gov (United States)

    Bortolotti, Laura; Granato, Anna; Laurenson, Lynn; Roberts, Katherine; Gallina, Albino; Silvester, Nicholas; Medrzycki, Piotr; Renzi, Teresa; Sgolastra, Fabio; Lodesani, Marco

    2016-01-01

    In Italy a nation-wide monitoring network was established in 2009 in response to significant honey bee colony mortality reported during 2008. The network comprised of approximately 100 apiaries located across Italy. Colonies were sampled four times per year, in order to assess the health status and to collect samples for pathogen, chemical and pollen analyses. The prevalence of Nosema ceranae ranged, on average, from 47–69% in 2009 and from 30–60% in 2010, with strong seasonal variation. Virus prevalence was higher in 2010 than in 2009. The most widespread viruses were BQCV, DWV and SBV. The most frequent pesticides in all hive contents were organophosphates and pyrethroids such as coumaphos and tau-fluvalinate. Beeswax was the most frequently contaminated hive product, with 40% of samples positive and 13% having multiple residues, while 27% of bee-bread and 12% of honey bee samples were contaminated. Colony losses in 2009/10 were on average 19%, with no major differences between regions of Italy. In 2009, the presence of DWV in autumn was positively correlated with colony losses. Similarly, hive mortality was higher in BQCV infected colonies in the first and second visits of the year. In 2010, colony losses were significantly related to the presence of pesticides in honey bees during the second sampling period. Honey bee exposure to poisons in spring could have a negative impact at the colony level, contributing to increase colony mortality during the beekeeping season. In both 2009 and 2010, colony mortality rates were positively related to the percentage of agricultural land surrounding apiaries, supporting the importance of land use for honey bee health. PMID:27182604

  16. Preliminary results of radiation monitoring near uranium mines in Namibia EJOLT Project (DRAFT version)

    Energy Technology Data Exchange (ETDEWEB)

    Chareyron, Bruno

    2012-04-05

    As a part of the EJOLT (Environmental Justice Organizations Liability and Trade) project, EARTHLIFE Namibia and CRIIRAD (Commission for Independent Research and Information about Radiation) have organised visits in areas located in the vicinity of uranium mines in Namibia In the course of an on site mission carried out between September 22 and October 2 2011, scientists from the CRIIRAD laboratory took radiation measurements in situ, and collected 14 samples of top soil, 13 samples of surface sediments of the Swakop, Gawib and Khan rivers, 11 underground water samples in the alluvium of Swakop, and Khan rivers and tap water from Arandis city, and one sample of asparagus. Solid samples have been analysed at the CRIIRAD laboratory in France (measurements performed by HpGe gamma spectrometry) and water samples have been monitored for main chemicals by LDA 26 laboratory in France and for radium 226 and radon 222 at the CRIIRAD laboratory. Some of the preliminary findings are summarised in this report: 1 - The dose rate measured by CRIIRAD on the parking of Roessing mine is about 6 times above natural background value (0.9 {mu}Sv/h compared to 0.15 {mu}Sv/h); 2 - The management of waste rock dumps needs to be improved: Some waste rocks are dumped on the banks of Khan river (at the intersection with Dome Gorge) without fencing and confinement. The radiological impact of this activity has to be studied in detail but preliminary measurements show various impacts on the environment; 3 - The finest fraction of the radioactive tailings dumped on Roessing tailings dam is blown away by the wind and contaminates the surrounding environment; 4 - The high uranium concentration in underground water collected downstream Roessing uranium mine in the Khan river and Swakop river alluvium raises the question of the origin of this uranium

  17. Food Security Monitoring via Mobile Data Collection and Remote Sensing: Results from the Central African Republic.

    Science.gov (United States)

    Enenkel, Markus; See, Linda; Karner, Mathias; Álvarez, Mònica; Rogenhofer, Edith; Baraldès-Vallverdú, Carme; Lanusse, Candela; Salse, Núria

    2015-01-01

    The Central African Republic is one of the world's most vulnerable countries, suffering from chronic poverty, violent conflicts and weak disaster resilience. In collaboration with Doctors without Borders/Médecins Sans Frontières (MSF), this study presents a novel approach to collect information about socio-economic vulnerabilities related to malnutrition, access to resources and coping capacities. The first technical test was carried out in the North of the country (sub-prefecture Kabo) in May 2015. All activities were aimed at the investigation of technical feasibility, not at operational data collection, which requires a random sampling strategy. At the core of the study is an open-source Android application named SATIDA COLLECT that facilitates rapid and simple data collection. All assessments were carried out by local MSF staff after they had been trained for one day. Once a mobile network is available, all assessments can easily be uploaded to a database for further processing and trend analysis via MSF in-house software. On one hand, regularly updated food security assessments can complement traditional large-scale surveys, whose completion can take up to eight months. Ideally, this leads to a gain in time for disaster logistics. On the other hand, recording the location of every assessment via the smart phones' GPS receiver helps to analyze and display the coupling between drought risk and impacts over many years. Although the current situation in the Central African Republic is mostly related to violent conflict it is necessary to consider information about drought risk, because climatic shocks can further disrupt the already vulnerable system. SATIDA COLLECT can easily be adapted to local conditions or other applications, such as the evaluation of vaccination campaigns. Most importantly, it facilitates the standardized collection of information without pen and paper, as well as straightforward sharing of collected data with the MSF headquarters or other

  18. Results from a post-launch monitoring survey on consumer purchases of foods with added phytosterols in five European countries.

    Science.gov (United States)

    Willems, Julie I; Blommaert, Mireille A E; Trautwein, Elke A

    2013-12-01

    Phytosterols (plant sterols and stanols), in the form of phytosterol-esters, are used in food products as active ingredients to lower elevated blood low density lipoprotein-cholesterol concentrations. In Europe, plant sterol-esters gained Novel Foods authorisation in 2000. As a requirement of the authorisation, Unilever developed a post-launch monitoring program to monitor the use of products with added phytosterols. This paper reports findings from the 2011 post-launch monitoring survey on consumer purchase behaviour of foods with added phytosterols. 91,000 households in the Netherlands, Belgium, United Kingdom, France and Germany were included. 11,612 purchased foods with added phytosterols, including spreads, salad dressings, milk- and yoghurt-type products. The results show that 71-82% of households purchasing products with added phytosterols were 1-2 person households. These households were also purchasing the majority of the volume sold in each country (75-85%). The average phytosterol intakes per household were 0.35-0.86 g/day; well below the 1.5-3.0 g/day phytosterols needed to achieve a significant blood cholesterol lowering benefit. Post-launch monitoring is an accepted and useful tool to estimate the consumption behaviour amongst different consumer groups. Data show that average phytosterol intakes per household were well below 1g/day, suggesting that overconsumption is unlikely. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Sixteen years of X-ray monitoring of Sagittarius A*: Evidence for a decay of the faint flaring rate from 2013 August, 13 months before a rise in the bright flaring rate

    Science.gov (United States)

    Mossoux, Enmanuelle; Grosso, Nicolas

    2017-08-01

    Context. X-ray flaring activity from the closest supermassive black hole Sagittarius A* (Sgr A*) located at the center of our Galaxy has been observed since 2000 October 26 thanks to the current generation of X-ray facilities. In a study of X-ray flaring activity from Sgr A* using Chandra and XMM-Newton public observations from 1999 to 2014 and Swift monitoring in 2014, it was argued that the "bright and very bright" flaring rate has increased from 2014 August 31. Aims: As a result of additional observations performed in 2015 with Chandra, XMM-Newton, and Swift (total exposure of 482 ks), we seek to test the significance and persistence of this increase of flaring rate and to determine the threshold of unabsorbed flare flux or fluence leading to any change of flaring rate. Methods: We reprocessed the Chandra, XMM-Newton, and Swift data from 1999 to 2015 November 2. From these data, we detected the X-ray flares via our two-step Bayesian blocks algorithm with a prior on the number of change points properly calibrated for each observation. We improved the Swift data analysis by correcting the effects of the target variable position on the detector and we detected the X-ray flares with a 3σ threshold on the binned light curves. The mean unabsorbed fluxes of the 107 detected flares were consistently computed from the extracted spectra and the corresponding calibration files, assuming the same spectral parameters. We constructed the observed distribution of flare fluxes and durations from the XMM-Newton and Chandra detections. We corrected this observed distribution from the detection biases to estimate the intrinsic distribution of flare fluxes and durations. From this intrinsic distribution, we determined the average flare detection efficiency for each XMM-Newton, Chandra, and Swift observation. We finally applied the Bayesian blocks algorithm on the arrival times of the flares corrected from the corresponding efficiency. Results: We confirm a constant overall flaring

  20. Functional and anatomical results after a single intravitreal Ozurdex injection in retinal vein occlusion: a 6-month follow-up -- the SOLO study.

    Science.gov (United States)

    Bezatis, Athanasios; Spital, Georg; Höhn, Fabian; Maier, Mathias; Clemens, Christoph R; Wachtlin, Joachim; Lehmann, Florian; Hattenbach, Lars Olof; Feltgen, Nicolas; Meyer, Carsten H

    2013-08-01

    To evaluate the efficacy of intravitreal dexamethasone implants in eyes with cystoid macular oedema (CME) secondary to branch retinal vein occlusion (BRVO) or central retinal vein occlusion (CRVO) in the clinical everyday practice, examine the effects of early retreatment and compare the results with the GENEVA study. The charts of 102 patients (102 eyes) with CME secondary to BRVO (n = 54) or CRVO (n = 48) treated with Ozurdex at 8 centres were retrospectively reviewed. The patients were examined monthly over a 24-week period. Slit-lamp biomicroscopy, measurement of best-corrected visual acuity (BCVA) and measurement of the central retinal thickness (CRT) with spectral-domain optical coherence tomography (SD-OCT) were performed at baseline and at every follow-up examination. With progression of the disease (loss of one line or increased central retinal thickness (CRT) of 150 μm), a reinjection of Ozurdex or anti-VEGF was offered. Additional supplementing sectorial or panretinal laser photocoagulation was considered based on the individual status of the retina. In the BRVO group, the median BCVA was 0.6 logMAR (Snellen equivalent of 0.25) at baseline and improved to 0.4 logMAR (Snellen equivalent of 0.40) after 4 weeks, 0.3 logMAR (Snellen equivalent of 0.50) after 8 weeks, 0.4 logMAR (Snellen equivalent of 0.40) after 12 weeks, 0.5 logMAR (Snellen equivalent of 0.32) after 16 weeks, 0.4 logMAR (Snellen equivalent of 0.40) after 20 weeks and 0.45 logMAR (Snellen equivalent of 0.35) after 24 weeks. The mean CRT was 559 ± (SD) 209 μm at baseline and it decreased to 335 ± 148 μm after 4 weeks, 316 ± 137 μm after 8 weeks, 369 ± 126 μm after 12 weeks, 407 ± 161 μm after 16 weeks, 399 ± 191 μm after 20 weeks and 419 ± 196 μm after 24 weeks. In the CRVO group, the median BCVA was 0.7 logMAR (Snellen equivalent of 0.20) at baseline and improved to 0.4 logMAR (Snellen equivalent of 0.40) after 4 weeks, 0.4 logMAR (Snellen equivalent of 0.40) after 8 weeks, 0

  1. Comparable Renal Function at 6 Months with Tacrolimus Combined with Fixed-Dose Sirolimus or MMF: Results of a Randomized Multicenter Trial in Renal Transplantation.

    Science.gov (United States)

    Van Gurp, Eveline; Bustamante, Jesus; Franco, Antonio; Rostaing, Lionel; Becker, Thomas; Rondeau, Eric; Czajkowski, Zenon; Rydzewski, Andrzej; Alarcon, Antonio; Bachleda, Petr; Samlik, Jiri; Burmeister, Dirk; Pallardo, Luis; Moal, Marie-Christine; Rutkowski, Boleslaw; Wlodarczyk, Zbigniew

    2010-01-01

    In a multicenter trial, renal transplant recipients were randomized to tacrolimus with fixed-dose sirolimus (Tac/SRL, N = 318) or tacrolimus with MMF (Tac/MMF, N = 316). Targeted tacrolimus trough levels were lower in the Tac/SRL group after day 14. The primary endpoint was renal function at 6 months using creatinine clearance (Cockcroft-Gault) and was comparable at 66.4 mL/min (SE 1.4) with Tac/SRL and at 65.2mL/min (SE 1.3) with Tac/MMF (completers). Biopsy-confirmed acute rejection was 15.1% (Tac/SRL) and 12.3% (Tac/MMF). In both groups, graft survival was 93% and patient survival was 99.0%. Premature withdrawal due to an adverse event was twice as high in the Tac/SRL group, 15.1% versus 6.3%. Hypercholesterolemia incidence was higher with Tac/SRL (P MMF (P 30 consecutive days in previously nondiabetic patients was 17.8%, Tac/SRL, and 24.8%, Tac/MMF. Evaluation at 6 months showed comparable renal function using tacrolimus/sirolimus and tacrolimus/MMF regimens.

  2. Is primary prevention of childhood obesity by education at 13-month immunisations feasible and acceptable? Results from a general practice based pilot study.

    LENUS (Irish Health Repository)

    Doorley, E

    2015-01-01

    Abstract Prevalence of childhood overweight and obesity remains high in Ireland. In this study an intervention conducted within primary care was evaluated. This involved a structured discussion with parents at the 13 month immunisations with their general practitioner (GP), including measuring weight of the toddler and parental education regarding healthy nutrition and physical activity for their toddler. There was a telephone follow-up interview with parents three months later assessing change in toddler diet\\/lifestyle. Endpoints assessed included parents\\' reports of specific lifestyle parameters with regard to the toddler and parental assessment of the usefulness of the intervention. 39 toddlers were studied. Most lifestyle parameters had improved at follow up. Reported fruit and vegetable intake of more than 4 portions per day increased from 20.5% of toddlers at baseline 28.6% at follow up. The number of toddlers abstaining from unhealthy snacks increased from 15.4% to 21.4%. Television watching of more than 2 hours daily decreased from 12.8% to 0%. Supervised exercise of more than thirty minutes per day increased from 69.2% to 89.3%. The majority of parents reported at follow up that they found the intervention acceptable (100%, n = 28) and useful (79%, n = 22).

  3. Feasibility of Metatranscriptome Analysis from Infant Gut Microbiota: Adaptation to Solid Foods Results in Increased Activity of Firmicutes at Six Months

    Directory of Open Access Journals (Sweden)

    Floor Hugenholtz

    2017-01-01

    Full Text Available Newborns are rapidly colonized by microbes and their intestinal tracts contain highly dynamic and rapidly developing microbial communities in the first months of life. In this study, we describe the feasibility of isolating mRNA from rapidly processed faecal samples and applying deep RNA-Seq analysis to provide insight into the active contributors of the microbial community in early life. Specific attention is given to the impact of removing rRNA from the mRNA on the phylogenetic and transcriptional profiling and its analysis depth. A breastfed baby was followed in the first six months of life during adaptation to solid food, dairy products, and formula. It was found that, in the weaning period, the total transcriptional activity of Actinobacteria, mainly represented by Bifidobacterium, decreased while that of Firmicutes increased over time. Moreover, Firmicutes and Actinobacteria, including the canonical Bifidobacteria as well as Collinsella, were found to be important contributors to carbohydrate fermentation and vitamin biosynthesis in the infant intestine. Finally, the expression of Lactobacillus rhamnosus-like genes was detected, likely following transfer from the mother who consumed L. rhamnosus GG. The study indicates that metatranscriptome analysis of the infant gut microbiota is feasible on infant stool samples and can be used to provide insight into the core activities of the developing community.

  4. Effects of a Psychoeducational Intervention for Direct Care Workers Caring for People With Dementia: Results From a 6-Month Follow-Up Study.

    Science.gov (United States)

    Barbosa, Ana; Nolan, Mike; Sousa, Liliana; Marques, Alda; Figueiredo, Daniela

    2016-03-01

    This study aimed to assess the effects of a psychoeducational intervention, designed to improve direct care workers' stress, burnout and job satisfaction, and person-centered communicative behavior in people with dementia. A pretest-posttest control group design was conducted in 4 aged-care facilities. Two experimental facilities received a psychoeducational intervention, and 2 control facilities received an education only. Data were gathered from 53 care workers at baseline, immediately, and 6 months after the intervention, through self-administrated instruments and video-recorded morning care sessions. The experimental group showed a significant decrease in care workers' burnout and a significant improvement in several communicative behaviors (e.g., involvement). Stress levels deteriorated at 6 months, and no intervention effects were found for job satisfaction. The findings highlight the importance of providing care workers with both technical competences and tools for stress management, as this might be associated with a reduction in their levels of exhaustion and improved communicative behaviors. © The Author(s) 2015.

  5. On the importance of a correct divulgation of monitoring results for an efficient management of landslide emergencies

    Science.gov (United States)

    Giordan, Daniele; Manconi, Andrea; Allasia, Paolo

    2015-04-01

    In the last decades, technological evolution has strongly increased the number of instruments that can be used to monitor landslide phenomena. Robotized Total Stations, GB-InSAR, and GPS are only few examples of the systems that can be used for the control of the topographic changes due to the landslide activity. These monitoring systems are often merged in a complex network, aimed at controlling the most important physical parameters influencing the evolution of landslide activity. The technological level reached by these systems allows us to use them for early warning purposes. Critical thresholds are identified and, when overcome, emergency actions are associated to protect population living in areas potentially involved by landslide failure. The use of these early warning systems can be very useful for the decision makers, which have to manage emergency conditions due to a landslide acceleration likely precursor of a collapse. At this stage, every instrument has a proper management system and the dataset obtained is often not compatible with the results of the others systems. The level of complexity increases with the number of monitoring systems and often could generate a paradox: the source of data are so numerous and difficult to interpret that a full understanding of the phenomenon could be hampered. Nowadays, a correct divulgation of the recent evolution of a landslide potentially dangerous for the population is very important. The Geohazard Monitoring Group of CNR IRPI developed a communication strategy to divulgate the monitoring network results based on both, a dedicated web page (for the publication in near real time of last updates), and periodical bulletins (for a deeper analysis of the available dataset). To manage the near real time application we developed a system called ADVICE (ADVanced dIsplaCement monitoring system for Early warning) that collects all the available data of a monitoring network and creates user-friendly representations of the

  6. Treatment of trochanteric fractures with the gamma3 nail - methodology and early results of a prospective consecutive monitored clinical case series.

    Science.gov (United States)

    A C, Unger; E, Wilde; B, Kienast; C, Jürgens; A P, Schulz

    2014-01-01

    There is only sparse data on clinical results and complications of the third-generation Gamma nailing system (Gamma3, Stryker). Therefore, we started a large multi-centre case series in 2008. The aim of this paper is to present the study design and early results of a single arm of a prospective, consecutive, monitored, post-market follow-up evaluation of Gamma3 nails. From September 2009 to January 2012, 154 consecutive patients with an average age of 80 ± 1.43 years (50-99 years) and a trochanteric femoral fracture were included in the local arm of the trial. All patients that fulfilled the inclusion criteria were treated with a Gamma3 nail. Preoperative variables included age, gender, fracture classification, walking ability (Merle d'Aubigné score), daily activity level (retrospective Zuckerman score), ASA rating of operative risk, waiting time for operation, use of walker or crutches and body mass index (BMI). Skin-to-skin time, fluoroscopy time, blood loss, intraoperative complications and device information were recorded for each patient. Follow-up postoperative assessment was undertaken at 4, 12 and 24 months. Hip range of motion, pain around the hip and the tight, walking ability (Merle d'Aubigné score, Sahlgrenska mobility score) and management of daily life (Zuckerman score) were used to evaluate the outcome. The descriptive data of age, gender, BMI, ASA classification, fracture type and skin-to-skin time is similar to other studies. Median fluoroscopy time was 62 seconds (range: 4-225 seconds) and significantly shorter in closed reductions. No intraoperative implant-related complication was recorded. A cut-out of the leg-screw during assessment period occurred in 2.6% patients (n = 4). At the 12-month assessment two (1.8%) non-unions were identified and two patients (1.8%) had broken the femoral shaft below the 180 mm nail after a fall. Analysis of the scores showed significantly declined mobility and activity in daily life four months after operation

  7. Regulatory competence and social communication in term and preterm infants at 12 months corrected age. Results from a randomized controlled trial.

    Science.gov (United States)

    Olafsen, Kåre S; Rønning, John A; Handegård, Bjørn Helge; Ulvund, Stein Erik; Dahl, Lauritz Bredrup; Kaaresen, Per Ivar

    2012-02-01

    Temperamental regulatory competence and social communication in term and preterm infants at 12 months corrected age was studied in a randomized controlled intervention trial aimed at enhancing maternal sensitive responsiveness. Surviving infants competence was measured with the Infant Behavior Questionnaire, and social communication with the Early Social Communication Scales. Preterm intervention infants with low regulatory competence had higher responding to joint attention than preterm control infants. A sensitizing intervention may moderate the association between temperament and social communication, and thus allow an alternative functional outlet for preterm infants low in regulatory competence. The finding may have implications for conceptualizations of the role of early sensitizing interventions in promoting important developmental outcomes for premature infants. Copyright © 2011 Elsevier Inc. All rights reserved.

  8. The results of ab interno laser thermal sclerostomy combined with cataract surgery versus trabeculectomy combined with cataract surgery 6 to 12 months postoperatively.

    Science.gov (United States)

    Kendrick, R; Kollarits, C R; Khan, N

    1996-07-01

    When cataract surgery and glaucoma surgery are combined, the theoretical advantages of pressure control, removal of the visual impairment, and protection against an increase in intraocular pressure (IOP) in the immediate postoperative period are gained. The authors' objective was to determine whether ab interno laser thermal sclerostomy (LTS) combined with cataract surgery would be as effective as trabeculectomy combined with cataract surgery. Ab interno LTS was compared with trabeculectomy, retrospectively, for patients who had undergone combined cataract and glaucoma surgery. There was no significant difference in the numbers of patients using no medications or fewer medications at 6 and 12 months. There was a greater reduction in IOP in the LTS group. LTS may be better than trabeculectomy in combined cataract and glaucoma surgery because it reduces the IOP more. Compared with trabeculectomy, LTS is simpler to perform and adds less operating time to cataract surgery. Continued follow-up is recommended.

  9. Preliminary results