WorldWideScience

Sample records for monitoring study type

  1. A performance evaluation study of three types of alpha-track detector radon monitors

    International Nuclear Information System (INIS)

    Yeager, W.M.; Lucas, R.M.; Daum, K.A.; Sensintaffar, E.; Poppell, S.; Feldt, L.; Clarkin, M.

    1991-01-01

    Three models of alpha-track detector (ATD) Rn monitors were exposed in Environmental Protection Agency (EPA) Rn chambers to obtain estimates of precision and bias for the National Residential Radon Survey (NRRS). Exposures in this study ranged from 37 to 740 Bq y m-3 (1 to 20 pCi y L-1), plus blanks. These exposures correspond to the range expected in most U.S. residences. All detectors were purchased through a Rn mitigation firm to assure that the vendors did not give special attention to the ATDs used in this study. Ten ATDs of each model were studied at 12 exposures. The mean and standard deviation of the reported values for each model were calculated and compared with the continuously monitored chamber concentrations to determine the bias and precision at each exposure. Results of this analysis were discussed with the vendors, who took corrective actions. Changes in track counting procedures and calibrations improved detector performance. Readings of one detector were adjusted based on a regression of the monitored values on the reported values

  2. Enhanced self-monitoring blood glucose in non-insulin requiring Type 2 diabetes: A qualitative study in primary care.

    Science.gov (United States)

    Brackney, Dana Elisabeth

    2018-03-31

    To contribute to both theoretical and practical understanding of the role of self-monitoring blood glucose for self-management by describing the experience of people with non-insulin requiring Type 2 diabetes in an enhanced structured self-monitoring blood glucose intervention. The complex context of self-monitoring blood glucose in Type 2 diabetes requires a deeper understanding of the clients' illness experience with structured self-monitoring of blood glucose. Clients' numeracy skills contribute to their response to blood glucose readings. Nurses' use of motivational interviewing to increase clients' regulatory self-efficacy is important to the theoretical perspective of the study. A qualitative descriptive study. A purposive sample of eleven adults recently (diabetes who had experienced a structured self-monitoring blood glucose intervention participated in this study. Audio recordings of semi-structured interviews and photos of logbooks were analyzed for themes using constant comparison and member checking. The illness experience states of Type 2 diabetes include 'Diagnosis', 'Behavior change', and 'Routine checking'. People check blood glucose to confirm their Type 2 diabetes diagnosis, to console their diabetes related fears, to create personal explanations of health behavior's impact on blood glucose, to activate behavior change and to congratulate their diabetes self-management efforts. These findings support the Transtheoretical model's stages of change and change processes. Blood glucose checking strengthens the relationships between theoretical concepts found in Diabetes Self-management Education-Support including: engagement, information sharing, and behavioral support. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  3. Systematic review of economic evaluation studies and budget impact on ambulatory monitoring of capillary glucose in type 2 diabetics.

    Science.gov (United States)

    Olry de Labry Lima, Antonio; Moya Garrido, María Natividad; Espín Balbino, Jaime

    2014-04-01

    Realise a review of studies of economic evaluation about the ambulatory monitoring of capillary glucose (AMGC) in diabetic type II persons. A review of the literature was conducted, in MedLine, various websites, referenced paper and provided by expert's persons. Five studies concluded that the AMGC was a cost-effective strategic, of this papers use Kaiser Permanente data base, its make that these studies could be considered a solely one study. The rest of the papers did not find difference in the AMGC use. The use of AMGC has an uncertainty efficiency. More studies are needed. Copyright © 2013 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.

  4. Classifying Multiple Types of Hand Motions Using Electrocorticography During Intraoperative Awake Craniotomy & Seizure Monitoring Processes - Case Studies

    Directory of Open Access Journals (Sweden)

    Tao eXie

    2015-10-01

    Full Text Available In this work, some case studies were conducted toclassify several kinds of hand motions from electrocorticography(ECoG signals during intraoperative awake craniotomy &extraoperative seizure monitoring processes. Four subjects (P1,P2 with intractable epilepsy during seizure monitoring and P3,P4 with brain tumor during awake craniotomy participatedin the experiments. Subjects performed three types of handmotions (Grasp, Thumb-finger motion and Index-finger motioncontralateral to the motor cortex covered with ECoG electrodes.Two methods were used for signal processing. Method I:autoregressive (AR model with burg method was applied toextract features, and additional waveform length (WL featurehas been considered, finally the linear discriminative analysis(LDA was used as the classifier. Method II: stationary subspaceanalysis (SSA was applied for data preprocessing, and thecommon spatial pattern (CSP was used for feature extractionbefore LDA decoding process. Applying method I, the threeclassaccuracy of P1□P4 were 90.17%, 96.00%, 91.77% and92.95% respectively. For method II, the three-class accuracy ofP1□P4 were 72.00%, 93.17%, 95.22% and 90.36% respectively.This study verified the possibility of decoding multiple handmotion types during an awake craniotomy, which is the firststep towards dexterous neuroprosthetic control during surgicalimplantation, in order to verify the optimal placement of electrodes.The accuracy during awake craniotomy was comparableto results during seizure monitoring. This study also indicatedthat ECoG was a promising approach for precise identificationof eloquent cortex during awake craniotomy, and might forma promising BCI system that could benefit both patients andneurosurgeons.

  5. Classifying multiple types of hand motions using electrocorticography during intraoperative awake craniotomy and seizure monitoring processes—case studies

    Science.gov (United States)

    Xie, Tao; Zhang, Dingguo; Wu, Zehan; Chen, Liang; Zhu, Xiangyang

    2015-01-01

    In this work, some case studies were conducted to classify several kinds of hand motions from electrocorticography (ECoG) signals during intraoperative awake craniotomy & extraoperative seizure monitoring processes. Four subjects (P1, P2 with intractable epilepsy during seizure monitoring and P3, P4 with brain tumor during awake craniotomy) participated in the experiments. Subjects performed three types of hand motions (Grasp, Thumb-finger motion and Index-finger motion) contralateral to the motor cortex covered with ECoG electrodes. Two methods were used for signal processing. Method I: autoregressive (AR) model with burg method was applied to extract features, and additional waveform length (WL) feature has been considered, finally the linear discriminative analysis (LDA) was used as the classifier. Method II: stationary subspace analysis (SSA) was applied for data preprocessing, and the common spatial pattern (CSP) was used for feature extraction before LDA decoding process. Applying method I, the three-class accuracy of P1~P4 were 90.17, 96.00, 91.77, and 92.95% respectively. For method II, the three-class accuracy of P1~P4 were 72.00, 93.17, 95.22, and 90.36% respectively. This study verified the possibility of decoding multiple hand motion types during an awake craniotomy, which is the first step toward dexterous neuroprosthetic control during surgical implantation, in order to verify the optimal placement of electrodes. The accuracy during awake craniotomy was comparable to results during seizure monitoring. This study also indicated that ECoG was a promising approach for precise identification of eloquent cortex during awake craniotomy, and might form a promising BCI system that could benefit both patients and neurosurgeons. PMID:26483627

  6. Glucose control in pregnant women with type 1 diabetes mellitus: Studies using a continuous glucose monitoring system

    NARCIS (Netherlands)

    Kerssen, Anneloes

    2005-01-01

    Pregnancy in women with type 1 diabetes mellitus is associated with neonatal morbidity. It is commonly agreed that the morbidity decreases when diabetic control is tightened. The most common methods for the determination of diabetic control are the self-monitoring of blood glucose levels (SMBG) and

  7. A qualitative case study of telehealth for in-home monitoring to support the management of type 2 diabetes.

    Science.gov (United States)

    Carlisle, Karen; Warren, Robin

    2013-10-01

    The present study formed part of a randomised controlled trial of telehealth for in-home monitoring to support people with poorly controlled type 2 diabetes. We explored the experiences of patients and healthcare practitioners, and their perceptions of the telehealth model of care used in the trial. In addition to their usual diabetes care, participants receive diabetes care from a diabetes educator nurse via an in-home broadband communication device. On average, each patient participated in 14 videoconferences with a diabetes care coordinator during the 12-month trial period. Qualitative data was collected from two general practices and included semi-structured interviews and document review of patient clinical notes. A total of 12 people were interviewed: 8 health practitioners and 4 patients. Patients and health practitioners expressed a high level of satisfaction with the model of care provided. Patients also reported positive health and social outcomes as a result of being involved in the trial and indicated that in the main they had achieved their goals and were happy with their progress over the 12-month period. Analysis of interviews revealed three broad elements associated with the implementation of telehealth: interpersonal factors, operational problems and the wider health system context within which the general practices and trial team were operating. The findings suggest that adopting telehealth in the management of type 2 diabetes can lead to improved diabetes control, but more support is required to ensure sustainability and widespread implementation.

  8. The role of cognitive operations in reality monitoring: a study with healthy older adults and Alzheimer's-type dementia.

    Science.gov (United States)

    Fairfield, Beth; Mammarella, Nicola

    2009-01-01

    The authors examined the role of cognitive operations in discriminations between externally and internally generated events (e.g., reality monitoring) in healthy and pathological aging. The authors used 2 reality-monitoring distinctions to manipulate the quantity and quality of necessary cognitive operations: discriminating between I performed versus I imagined performing and between I watched another perform versus I imagined another performing. Older adults had more difficulty than did younger adults when discriminating between memories in both versions of the task. In addition, older adults with Alzheimer's-type dementia showed marked difficulties when attributing a source to imagined actions. The authors interpret these findings in terms of an age difficulty or the failure to use cognitive operations as useful cues during source monitoring.

  9. Is type 2 diabetes really resolved after laparoscopic sleeve gastrectomy? Glucose variability studied by continuous glucose monitoring.

    Science.gov (United States)

    Capoccia, D; Coccia, F; Guida, A; Rizzello, M; De Angelis, F; Silecchia, G; Leonetti, F

    2015-01-01

    The study was carried out on type 2 diabetic obese patients who underwent laparoscopic sleeve gastrectomy (LSG). Patients underwent regular glycemic controls throughout 3 years and all patients were defined cured from diabetes according to conventional criteria defined as normalization of fasting glucose levels and glycated hemoglobin in absence of antidiabetic therapy. After 3 years of follow-up, Continuous Glucose Monitoring (CGM) was performed in each patient to better clarify the remission of diabetes. In this study, we found that the diabetes resolution after LSG occurred in 40% of patients; in the other 60%, even if they showed a normal fasting glycemia and A1c, patients spent a lot of time in hyperglycemia. During the oral glucose tolerance test (OGTT), we found that 2 h postload glucose determinations revealed overt diabetes only in a small group of patients and might be insufficient to exclude the diagnosis of diabetes in the other patients who spent a lot of time in hyperglycemia, even if they showed a normal glycemia (<140 mg/dL) at 120 minutes OGTT. These interesting data could help clinicians to better individualize patients in which diabetes is not resolved and who could need more attention in order to prevent chronic complications of diabetes.

  10. Study on Turn-to-turn Short Circuit On一line Monitoring System for Dry一type Ai r一core Reactor

    Directory of Open Access Journals (Sweden)

    GAO Zi-wei

    2017-04-01

    Full Text Available The change of current value caused by turn-to-turn short circuit of dry-type air-core reactor is so little that failure detection is difficult to be carried out. In order to solve this problem,a new on-line monitoring system based on impedance variation of turn-to-turn short circuit is proposed. The numerical method is applied to analyze the variation of equivalent resistance and equivalent reactance when dry-type air-core reactor winding short circuit happens in different places,and the monitoring method based on harmonic analysis method and quasi- synchronization sampling method is analyzed by theory. The hardware system,which takes single-chip microcomputer as the core of data processing and logic control,completes data acquisition of voltage signal and current signal of the reactor. In the respect of software design,the impedance variation will be uploaded to the PC after it has been calculated by using the above monitoring method,and then monitoring of turn-to-turn short circuit fault will be realized. Finally,the design of on-line monitoring system is studied by testing. The research result shows that,the equivalent resistance increases and the equivalent reactance decreases when turn-to-turn short circuit occurs,and the variation of equivalent resistance is more obvious than equivalent reactance. The experiment results prove that this monitoring method is true and the on-line monitoring system is feasible.

  11. Perspectives of patients with type 1 or insulintreated type 2 diabetes on self-monitoring of blood glucose : a qualitative study

    NARCIS (Netherlands)

    Hortensius, Johanna; Kars, Marijke C.; Wierenga, Willem S.; Kleefstra, Nanne; Bilo, Henk J. G.; van der Bijl, Jaap J.

    2012-01-01

    Background: Self-monitoring of blood glucose (SMBG), including self-regulation, is an important tool to achieve good glycemic control. However, many patients measure their glucose concentrations less often than is recommended. This study investigates patients' perspectives of SMBG and all relevant

  12. Self-monitoring of Blood Glucose in Non-Insulin Treated Type 2 Diabetes (The SMBG Study): study protocol for a randomised controlled trial.

    Science.gov (United States)

    Parsons, Sharon; Luzio, Stephen; Bain, Stephen; Harvey, John; McKenna, Jillian; Khan, Atir; Rice, Sam; Watkins, Alan; Owens, David R

    2017-01-26

    The benefit of Self-monitoring of Blood Glucose (SMBG) in people with non-insulin treated type 2 diabetes remains unclear with inconsistent evidence from randomised controlled trials fuelling the continued debate. Lack of a consistent finding has been attributed to variations in study population and design, including the SMBG intervention. There is a growing consensus that structured SMBG, whereby the person with diabetes and health care provider are educated to detect patterns of glycaemic abnormality and take appropriate action according to the blood glucose profiles, can prove beneficial in terms of lowering HbA1c and improving overall well-being. Despite this, many national health agencies continue to issue guidelines restricting the use of SMBG in non-insulin treated type 2 diabetes. The SMBG Study is a 12 month, multi-centre, randomised controlled trial in people with type 2 diabetes not on insulin therapy who have poor glycaemic control (HbA1c ≥58 mmol/mol / 7.5%). The participants will be randomised into three comparative groups: Group 1 will act as a control group and receive their usual diabetes care; Group 2 will undertake structured SMBG with clinical review every 3 months; Group 3 will undertake structured SMBG with additional monthly telecare support from a trained study nurse. A total of 450 participants will be recruited from 16 primary and secondary care sites across Wales and England. The primary outcome measure will be HbA1c at 12 months with secondary measures to include weight, BMI, total cholesterol and HbA1c levels at 3, 6, 9 and 12 months. Participant well-being and attitude towards SMBG will be monitored throughout the course of the study. Recruitment began in December 2012 with the last participant visit due in September 2016. This study will attempt to answer the question of whether structured SMBG provides any benefits to people with poorly controlled type 2 diabetes who are not being treated with insulin. The data will also

  13. Efficient monitoring of type 2 diabetes in primary care

    NARCIS (Netherlands)

    Wermeling, P.R.

    2013-01-01

    Guidelines for treatment of patients with type 2 diabetes mellitus advise to monitor patients every three months, but this advice is not evidence-based. In this study we investigated whether the monitoring frequency in well-controlled diabetes patients (not using insulin, HbA1c ≤58 mmol/mol,

  14. Hanger-type laundry monitor system

    International Nuclear Information System (INIS)

    Aoyama, Kei; Kouno, Yoshio; Yanagishima, Ryouhei; Ikeda, Yasuyuki; Nakatani, Masahiro

    1987-01-01

    Laundry monitor is installed in nuclear power plants or other nuclear facilities in order to efficiently detect radioactive contamination remains on the surfaces of the working clothes which were used in the controlled area and washed afterward. The number of the working clothes which must be measured has been increasing in accordance with the increase of the nuclear facilities. This fact and recent intensified radiation control require automatic, high-speed and high sensitive measurement. Conveyer-type laundry monitor in which the working clothes are inserted by the metal net conveyer has been generally used, and recently new system with an automatic folder has become more popular. But, this type of system has not so big capacity because the clothes are conveyed longitudinally and also requires considerable wide space when installed. Fuji electric Co., Ltd. has been engaging in research and development for an optimum laundry monitor system used in nuclear facilities since the joint investigation with ten electric power companies in Japan in 1982. Consequently hanger-type laundry monitor system using automatic hanger conveyer was developed and 2 systems were delivered to Chubu Electric Power Co., Ltd. in 1986. This system permits to detect radioactive contamination on the working clothes, pick the contaminated clothes out and fold the uncontaminated clothes fully automatically and continuously. Moreover it allows to shorten the measurement time because the clothes are conveyed transversely and save the installation space, so that this will be regarded as considerably complete system in the world. This report describes the outline of the hanger-type laundry monitor system. (author)

  15. Travelling type monitoring and inspection device

    International Nuclear Information System (INIS)

    Ito, Takao; Maruki, Hideaki.

    1994-01-01

    The present invention sufficiently ensures video output images even if lenses of a television camera of a monitoring means are degraded to reduce the quantity of transmission light. That is, a light amount control mechanism capable of controlling the quantity of illumination light irradiated from an illumination device at an output level of a sensor of an inspection device main body. A test chart for measuring a luminance which is an output level of the sensor is disposed. During plant operation, the lenses of the television camera undergo influences of radioactivity and are degraded to reduce the quantity of transmission light on every periodical monitoring and inspection using a travelling type monitoring inspection device. In this case, the test chart disposed near the equipment to be monitored and inspected is caught by the television camera to measure a sensor output luminance. Then, the light amount control mechanism of the illumination device is controlled so as to provide a luminance which has been set at an initial stage of the plant inspection. With such procedures, video data of the objective equipment to be monitored and inspected can be obtained at a constant luminance during inspection. (I.S.)

  16. Customization of home closed-loop insulin delivery in adult patients with type 1 diabetes, assisted with structured remote monitoring: the pilot WP7 Diabeloop study.

    Science.gov (United States)

    Benhamou, Pierre Yves; Huneker, Erik; Franc, Sylvia; Doron, Maeva; Charpentier, Guillaume

    2018-06-01

    Improvement in closed-loop insulin delivery systems could result from customization of settings to individual needs and remote monitoring. This pilot home study evaluated the efficacy and relevance of this approach. A bicentric clinical trial was conducted for 3 weeks, using an MPC-based algorithm (Diabeloop Artificial Pancreas system) featuring five settings designed to modulate the reactivity of regulation. Remote monitoring was ensured by expert nurses with a web platform generating automatic Secured Information Messages (SIMs) and with a structured procedure. Endpoints were glucose metrics and description of impact of monitoring on regulation parameters. Eight patients with type 1 diabetes (six men, age 41.8 ± 11.4 years, HbA1c 7.7 ± 1.0%) were included. Time spent in the 70-180 mg/dl range was 70.2% [67.5; 76.9]. Time in hypoglycemia < 70 mg/dl was 2.9% [2.1; 3.4]. Eleven SIMs led to phone intervention. Original default settings were modified in all patients by the intervention of the nurses. This pilot trial suggests that the Diabeloop closed-loop system could be efficient regarding metabolic outcomes, whereas its telemedical monitoring feature could contribute to enhanced efficacy and safety. This study is registered at ClinicalTrials.gov with trial registration number NCT02987556.

  17. How are patients with type 2 diabetes and renal disease monitored and managed? Insights from the observational OREDIA study

    Directory of Open Access Journals (Sweden)

    Penfornis A

    2014-06-01

    Full Text Available Alfred Penfornis,1 Jean Frédéric Blicklé,2 Béatrice Fiquet,3 Stéphane Quéré,4 Sylvie Dejager3 1Department of Endocrinology-Metabolism and Diabetology-Nutrition, Jean Minjoz Hospital, University of Franche-Comté, Besançon, France; 2Department of Internal Medicine and Diabetology, Strasbourg University Hospital, Strasbourg, France; 3Clinical Affairs, Novartis Pharma SAS, Rueil-Malmaison, France; 4BioStatistics, Novartis Pharma SAS, Rueil-Malmaison, France Background and aim: Chronic kidney disease (CKD is frequent in type 2 diabetes mellitus (T2DM, and therapeutic management of diabetes is more challenging in patients with renal impairment (RI. The place of metformin is of particular interest since most scientific societies now recommend using half the dosage in moderate RI and abstaining from use in severe RI, while the classic contraindication with RI has not been removed from the label. This study aimed to assess the therapeutic management, in particular the use of metformin, of T2DM patients with CKD in real life. Methods: This was a French cross-sectional observational study: 3,704 patients with T2DM diagnosed for over 1 year and pharmacologically treated were recruited in two cohorts (two-thirds were considered to have renal disease [CKD patients] and one-third were not [non-CKD patients] by 968 physicians (81% general practitioners in 2012. Results: CKD versus non-CKD patients were significantly older with longer diabetes history, more diabetic complications, and less strict glycemic control (mean glycated hemoglobin [HbA1c] 7.5% versus 7.1%; 25% of CKD patients had HbA1c ≥8% versus 15% of non-CKD patients. Fifteen percent of CKD patients had severe RI, and 66% moderate RI. Therapeutic management of T2DM was clearly distinct in CKD, with less use of metformin (62% versus 86% but at similar mean daily doses (~2 g/d. Of patients with severe RI, 33% were still treated with metformin, at similar doses. For other oral anti

  18. Strategies to prevent ventilation-associated pneumonia: the effect of cuff pressure monitoring techniques and tracheal tube type on aspiration of subglottic secretions: an in-vitro study.

    Science.gov (United States)

    Carter, Eleanor L; Duguid, Alasdair; Ercole, Ari; Matta, Basil; Burnstein, Rowan M; Veenith, Tonny

    2014-03-01

    Ventilation-associated pneumonia (VAP) is the commonest nosocomial infection in intensive care. Implementation of a VAP prevention care bundle is a proven method to reduce its incidence. The UK care bundle recommends maintenance of the tracheal tube cuff pressure at 20 to 30  cmH₂O with 4-hourly pressure checks and use of tracheal tubes with subglottic aspiration ports in patients admitted for more than 72  h. To evaluate the effects of tracheal tube type and cuff pressure monitoring technique on leakage of subglottic secretions past the tracheal tube cuff. Bench-top study. Laboratory. A model adult trachea with simulated subglottic secretions was intubated with a tracheal tube with the cuff inflated to 25  cmH₂O. Experiments were conducted using a Portex Profile Soft Seal tracheal tube with three cuff pressure monitoring strategies and using a Portex SACETT tracheal tube with intermittent cuff pressure checks. Rate of simulated secretion leakage past the tracheal tube cuff. Mean ± SD leakage of fluid past the Profile Soft Seal tracheal tube cuff was 2.25 ± 1.49  ml  min⁻¹ with no monitoring of cuff pressure, 2.98 ± 1.63  ml  min⁻¹ with intermittent cuff pressure monitoring and 3.83 ± 2.17  ml  min⁻¹ with continuous cuff pressure monitoring (P aspiration port and aspirating the simulated secretions prior to intermittent cuff pressure checks reduced the leakage rate to 0.50 ± 0.48  ml  min⁻¹ (P aspiration port. Further evaluation of medical device performance is needed in order to design more effective VAP prevention strategies.

  19. Perspectives of patients with non-insulin-treated type 2 diabetes on self-monitoring of blood glucose: A qualitative study.

    Science.gov (United States)

    Chen, Chen-Mei; Hung, Li-Chen; Chen, Yang-Lin; Yeh, Mei Chang

    2018-04-01

    To explore experiences of self-monitoring of blood glucose among patients with non-insulin-treated type 2 diabetes. Self-monitoring of blood glucose is essential to diabetes care and facilitates glycaemic control. Patients' perspectives of self-monitoring of blood glucose have seldom been discussed in the literature, and engagement in self-monitoring of blood glucose is consistently low. The descriptive phenomenological method was used. Purposive sampling was conducted to recruit participants from the endocrinology departments of medical institutions in Taiwan based on the following criteria: (i) having a medical diagnosis of type 2 diabetes, (ii) not being treated with insulin, (iii) having engaged in self-monitoring of blood glucose at least once within the preceding 6 months, (iv) being at least 20 years old and (v) not having any major mental or cognitive disorders. Data were collected in outpatient consultation rooms, the participants' homes and other settings where the participants felt secure and comfortable. In-depth interviews were conducted to collect data from 16 patients with diabetes. The participants perceived that lifestyle affected blood glucose levels and did not know how to handle high or low blood glucose levels. Their willingness to continue self-monitoring of blood glucose depended on whether healthcare professionals checked or discussed their blood glucose levels with them. The patients' knowledge regarding blood glucose variation and healthcare professionals' attitudes affected the patients' self-monitoring of blood glucose behaviours. The empirical findings illustrated self-monitoring of blood glucose experiences and recommended that healthcare professionals' closely attend to patients' requirements and responses to diabetes and incorporate the self-monitoring of blood glucose into therapy plans. Healthcare professionals should reinforce patients' knowledge on appropriate responses to high and low blood glucose levels, intervene

  20. Glycemic variability and insulin needs in patients with type 1 diabetes mellitus supplemented with vitamin D: a pilot study using continuous glucose monitoring system.

    Science.gov (United States)

    Felício, Karem Miléo; de Souza, Ana Carolina Contente Braga; Neto, João Felício Abrahão; de Melo, Franciane Trindade Cunha; Carvalho, Carolina Tavares; Arbage, Thaís Pontes; de Rider Brito, Hana Andrade; Peixoto, Amanda Soares; de Oliveira, Alana Ferreira; de Souza Resende, Fabricio; Reis, Scarlatt Sousa; Motta, Ana Regina; da Costa Miranda, Henrique; Janaú, Luísa Corrêa; Yamada, Elizabeth Sumi; Felício, João Soares

    2017-06-15

    Recent studies suggest that glycemic variability could influence the risk of complications in type 1 diabetes mellitus (T1DM). There are no data about the action of vitamin D (VD) on glycemic variability. Our pilot study aims to evaluate glycemic variability and insulin needs in patients with T1DM supplemented with VD. 22 patients received doses of 4000 and 10000 IU/day of cholecalciferol for 12 weeks, according to the patient's baseline VD levels and underwent continuous glucose monitoring system. Correlations were found between percentage variation (∆) of glycemia standard deviation (∆SDG), calculated using continuous glucose monitoring, with ∆ of basal (r= 0.6; p needed by patients is lower when VD status is better. We divided patients in two subgroups: SDG improved (subgroup 1; n =12 (55%)) and SDG worsened (subgroup 2; n =10 (45%)). Group 1, compared to subgroup 2, required a lower insulin dose (∆basal insulin dose = -8.0 vs 6.3%; p needs and lower frequency of hypoglycemia in patients with T1DM. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  1. Intracranial pressure monitoring in severe blunt head trauma: does the type of monitoring device matter?

    Science.gov (United States)

    Aiolfi, Alberto; Khor, Desmond; Cho, Jayun; Benjamin, Elizabeth; Inaba, Kenji; Demetriades, Demetrios

    2018-03-01

    OBJECTIVE Intracranial pressure (ICP) monitoring has become the standard of care in the management of severe head trauma. Intraventricular devices (IVDs) and intraparenchymal devices (IPDs) are the 2 most commonly used techniques for ICP monitoring. Despite the widespread use of these devices, very few studies have investigated the effect of device type on outcomes. The purpose of the present study was to compare outcomes between 2 types of ICP monitoring devices in patients with isolated severe blunt head trauma. METHODS This retrospective observational study was based on the American College of Surgeons Trauma Quality Improvement Program database, which was searched for all patients with isolated severe blunt head injury who had an ICP monitor placed in the 2-year period from 2013 to 2014. Extracted variables included demographics, comorbidities, mechanisms of injury, head injury specifics (epidural, subdural, subarachnoid, intracranial hemorrhage, and diffuse axonal injury), Abbreviated Injury Scale (AIS) score for each body area, Injury Severity Score (ISS), vital signs in the emergency department, and craniectomy. Outcomes included 30-day mortality, complications, number of ventilation days, intensive care unit and hospital lengths of stay, and functional independence. RESULTS During the study period, 105,721 patients had isolated severe traumatic brain injury (head AIS score ≥ 3). Overall, an ICP monitoring device was placed in 2562 patients (2.4%): 1358 (53%) had an IVD and 1204 (47%) had an IPD. The severity of the head AIS score did not affect the type of ICP monitoring selected. There was no difference in the median ISS; ISS > 15; head AIS Score 3, 4, or 5; or the need for craniectomy between the 2 device groups. Unadjusted 30-day mortality was significantly higher in the group with IVDs (29% vs 25.5%, p = 0.046); however, stepwise logistic regression analysis showed that the type of ICP monitoring was not an independent risk factor for death

  2. Wide area monitoring study

    International Nuclear Information System (INIS)

    Wogman, N.A.; Holdren, G.R. Jr.

    1999-01-01

    Environmental sampling can be used to complement the safeguarding of nuclear material, especially in the detection of undeclared nuclear activities. Routine monitoring of nuclear installations has provided valuable information about the fate of key signature materials within different environmental settings. The approach collates information regarding the generation of individual radiochemical signatures within different nuclear processes, the potential for release of these signatures to the environment and, the chemical form and mobility of the signatures in environmental media along which the material could migrate. Meteorological, geological and hydrological information is used to determine where to sample, what to sample, and how often to sample to provide the greatest likelihood for detection. Multiple strategies can be used to implement wide area monitoring for safeguards purposes. The most complex, and expensive of these, involves establishing extensive networks of fixed location sampling sites. The sites would be operated continuously, and would be instrumented with automated sampling, analysis, and communication equipment to relay information regarding potential anomalies to control centers in near-real time. Alternative strategies can be used to supplement fixed location monitoring equipment, especially in regions that cannot support (financially or logistically) the fixed stations. Through combinations of these various strategies, using a variety of environmental media to monitor a region, we believe that a competent network, one with a quantifiable probability for detecting undeclared nuclear activities, can be designed. While this approach cannot and should not replace other inspection and monitoring activities, it can potentially contribute valuable information to an international safeguards system. (author)

  3. Barriers and facilitators to self-monitoring of blood glucose in people with type 2 diabetes using insulin: a qualitative study

    Directory of Open Access Journals (Sweden)

    Ong WM

    2014-02-01

    Full Text Available Woon May Ong,1 Siew Siang Chua,1 Chirk Jenn Ng2 1Department of Pharmacy, 2University of Malaya Primary Care Research Group (UMPCRG, Department of Primary Care Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia Background: Self-monitoring of blood glucose (SMBG helps to improve glycemic control and empowerment of people with diabetes. It is particularly useful for people with diabetes who are using insulin as it facilitates insulin titration and detection of hypoglycemia. Despite this, the uptake of SMBG remains low in many countries, including Malaysia. Purpose: This study aimed to explore the barriers and facilitators to SMBG, in people with type 2 diabetes using insulin. Patients and methods: Qualitative methodology was employed to explore participants’ experience with SMBG. Semistructured, individual in-depth interviews were conducted on people with type 2 diabetes using insulin who had practiced SMBG, in the primary care clinic of a teaching hospital in Malaysia. Participants were purposively sampled from different age groups, ethnicity, education level, and level of glycemic control (as reflected by the glycated hemoglobin [HbA1c], to achieve maximum variation in sampling. All interviews were conducted using a topic guide and were audio-recorded, transcribed verbatim, checked, and analyzed using a thematic approach. Results: A total of 15 participants were interviewed, and thematic saturation was reached. The factors that influenced SMBG were mainly related to cost, participants' emotion, and the SMBG process. The barriers identified included: frustration related to high blood glucose reading; perception that SMBG was only for insulin titration; stigma; fear of needles and pain; cost of test strips and needles; inconvenience; unconducive workplace; and lack of motivation, knowledge, and self-efficacy. The facilitators were: experiencing hypoglycemic symptoms; desire to see the effects of dietary changes; desire to

  4. Analysis of the Accuracy and Performance of a Continuous Glucose Monitoring Sensor Prototype: An In-Silico Study Using the UVA/PADOVA Type 1 Diabetes Simulator.

    Science.gov (United States)

    Breton, Marc D; Hinzmann, Rolf; Campos-Nañez, Enrique; Riddle, Susan; Schoemaker, Michael; Schmelzeisen-Redeker, Guenther

    2017-05-01

    Computer simulation has been shown over the past decade to be a powerful tool to study the impact of medical devices characteristics on clinical outcomes. Specifically, in type 1 diabetes (T1D), computer simulation platforms have all but replaced preclinical studies and are commonly used to study the impact of measurement errors on glycemia. We use complex mathematical models to represent the characteristics of 3 continuous glucose monitoring systems using previously acquired data. Leveraging these models within the framework of the UVa/Padova T1D simulator, we study the impact of CGM errors in 6 simulation scenarios designed to generate a wide variety of glycemic conditions. Assessment of the simulated accuracy of each different CGM systems is performed using mean absolute relative deviation (MARD) and precision absolute relative deviation (PARD). We also quantify the capacity of each system to detect hypoglycemic events. The simulated Roche CGM sensor prototype (RCGM) outperformed the 2 alternate systems (CGM-1 & CGM-2) in accuracy (MARD = 8% vs 11.4% vs 18%) and precision (PARD = 6.4% vs 9.4% vs 14.1%). These results held for all studied glucose and rate of change ranges. Moreover, it detected more than 90% of hypoglycemia, with a mean time lag less than 4 minutes (CGM-1: 86%/15 min, CGM-2: 57%/24 min). The RCGM system model led to strong performances in these simulation studies, with higher accuracy and precision than alternate systems. Its characteristics placed it firmly as a strong candidate for CGM based therapy, and should be confirmed in large clinical studies.

  5. HbA1c monitoring interval in patients on treatment for stable type 2 diabetes. A ten-year retrospective, open cohort study.

    Science.gov (United States)

    Ohde, Sachiko; Deshpande, Gautam A; Yokomichi, Hiroshi; Takahashi, Osamu; Fukui, Tsuguya; Yamagata, Zentaro

    2018-01-01

    [Aims] This study aims to suggest an informative interval for HbA1c in DM patients with stable glycemic control, based on test characteristics of the HbA1C assay using the signal-to-noise ratio method. [Methods] This was a retrospective, open cohort study. Data were collected between January 2005 to December 2014 at a tertiary-level community hospital in Japan. All adult patients aged under 75 years, with stable glycemic control on a first pharmaceutical regimen for Type II diabetes, and at least two HbA1c measurements after they achieved glycemic stability, were included in the analysis. We defined stable glycemic control as HbA1c HbA1c. The screening interval for HbA1c was defined as informative when the signal-to-noise ratio exceeded 1. [Results] Among 1066 adults with diabetes, 639 patients (18.5%) were identified as achieving stable glycemic control (511 male (67.3%)), with a mean HbA1c (SD) of 6.4 (0.4)% (46 mmol/mol). Patients with stable glycemic control increase their HbA1c 0.27% (3 mmol/mol) every year while HbA1c has 0.32% (3.5 mmol/mol) noise, as testing characteristics. Signal exceeds noise after 1.2 years (95%CI: 0.9-1.6). [Conclusion] Once patients achieve stable glycemic control at their HbA1c goal, an informative interval for HbA1c monitoring is once every year. Current guidelines, which suggest testing every six months, may contribute to substantial over-testing. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  6. Continuous glucose monitoring systems for type 1 diabetes mellitus

    NARCIS (Netherlands)

    Langendam, Miranda; Luijf, Yoeri M.; Hooft, Lotty; DeVries, J. Hans; Mudde, Aart H.; Scholten, Rob J. P. M.

    2012-01-01

    Background Self-monitoring of blood glucose is essential to optimise glycaemic control in type 1 diabetes mellitus. Continuous glucose monitoring (CGM) systems measure interstitial fluid glucose levels to provide semi-continuous information about glucose levels, which identifies fluctuations that

  7. Core monitoring system for FBR type reactor

    International Nuclear Information System (INIS)

    Azekura, Kazuo.

    1981-01-01

    Purpose: To determine power distribution ON-line after the change of the insertion degree of control rods by the provision of means for calculating power change coefficient at each of the points due to the change in the insertion degree from the specific change of insertion degree and multiplying the same with the newest power distribution determined periodically by the diffusion calculation. Constitution: The monitoring system additionally comprises a calculation device for power change coefficient that calculates the power change coefficient in a fuel assembly adjacent to a control rod based on the data concerning the operation of the control rod, and a provisional power distribution calculation device that executes multiplication between the power distribution calculated in a periodical power distribution calculation device based on the calculation instruction and stored in the core and the power change coefficient from the power change coefficient calculation device and forecasts the provisional power distribution. Then, based on the result of the foregoing calculations, 2-dimensional power distribution, maximum temperature for the cladding tube of the specified fuel assembly, maximum temperature of pellets in the specified fuel assembly, maximum power density and the like are calculated in various display value calculation devices and displayed on a display device. (Horiuchi, T.)

  8. Development of fluctuation monitor type sodium ionization detector

    International Nuclear Information System (INIS)

    Yamamoto, Hajime; Sato, Yoshihiko; Ibe, Eishi; Suzuoki, Akira

    1986-01-01

    In order to improve the sensitivity and the reliability of the sodium leak detection system used in the fast breeder reactors, a new type SID (sodium ionization detector) has been developed, in which the monitored signal is only the fluctuating component of the current between the filament and the ion collector. The fluctuating component was extracted by a band pass filter and its root mean square value was calculated as the SID signal. Fluctuation characteristics of the output current were studied by its frequency spectrum. The results revealed that the current spectrum was affected by the particle size distribution of the aerosol and was most clearly distinguished from that of the background current in the frequency region of 0.5 ∼ 10 Hz. Output characteristics of the fluctuation monitor type SID (FM-SID) were obtained as a function of sodium concentration in the gas. The FM-SID sensitivity was lowered by impurities in the gas, such as oxygen and water vapor. Finally, in comparisons with the conventional DC-SIDs, the background noise level of the FM-SID was much lower and S/N ratio was greatly improved. The detectable sodium concentration level was ten times lower than that of the DC-SID. (author)

  9. Continuous glucose monitoring systems for type 1 diabetes mellitus.

    Science.gov (United States)

    Langendam, Miranda; Luijf, Yoeri M; Hooft, Lotty; Devries, J Hans; Mudde, Aart H; Scholten, Rob J P M

    2012-01-18

    Self-monitoring of blood glucose is essential to optimise glycaemic control in type 1 diabetes mellitus. Continuous glucose monitoring (CGM) systems measure interstitial fluid glucose levels to provide semi-continuous information about glucose levels, which identifies fluctuations that would not have been identified with conventional self-monitoring. Two types of CGM systems can be defined: retrospective systems and real-time systems. Real-time systems continuously provide the actual glucose concentration on a display. Currently, the use of CGM is not common practice and its reimbursement status is a point of debate in many countries. To assess the effects of CGM systems compared to conventional self-monitoring of blood glucose (SMBG) in patients with diabetes mellitus type 1. We searched The Cochrane Library, MEDLINE, EMBASE and CINAHL for the identification of studies. Last search date was June 8, 2011. Randomised controlled trials (RCTs) comparing retrospective or real-time CGM with conventional self-monitoring of blood glucose levels or with another type of CGM system in patients with type 1 diabetes mellitus. Primary outcomes were glycaemic control, e.g. level of glycosylated haemoglobin A1c (HbA1c) and health-related quality of life. Secondary outcomes were adverse events and complications, CGM derived glycaemic control, death and costs. Two authors independently selected the studies, assessed the risk of bias and performed data-extraction. Although there was clinical and methodological heterogeneity between studies an exploratory meta-analysis was performed on those outcomes the authors felt could be pooled without losing clinical merit. The search identified 1366 references. Twenty-two RCTs meeting the inclusion criteria of this review were identified. The results of the meta-analyses (across all age groups) indicate benefit of CGM for patients starting on CGM sensor augmented insulin pump therapy compared to patients using multiple daily injections of

  10. An exploratory trial of basal and prandial insulin initiation and titration for type 2 diabetes in primary care with adjunct retrospective continuous glucose monitoring: INITIATION study.

    Science.gov (United States)

    Blackberry, Irene D; Furler, John S; Ginnivan, Louise E; Manski-Nankervis, Jo-Anne; Jenkins, Alicia; Cohen, Neale; Best, James D; Young, Doris; Liew, Danny; Ward, Glenn; O'Neal, David N

    2014-11-01

    To evaluate basal and prandial insulin initiation and titration in people with type 2 diabetes mellitus (T2DM) in primary care and to explore the feasibility of retrospective-continuous glucose monitoring (r-CGM) in guiding insulin dosing. The new model of care features General Practitioners (GPs) and Practice Nurses (PNs) working in an expanded role, with Credentialed Diabetes Educator - Registered Nurse (CDE-RN) support. Insulin-naïve T2DM patients (HbA1c >7.5% [>58 mmol/mol] despite maximal oral therapy) from 22 general practices in Victoria, Australia commenced insulin glargine, with glulisine added as required. Each was randomised to receive r-CGM or self-monitoring of blood glucose (SMBG). Glycaemic control (HbA1c) was benchmarked against specialist ambulatory patients referred for insulin initiation. Ninety-two patients mean age (range) 59 (28-77) years; 40% female; mean (SD) diabetes duration 10.5 (6.1) years participated. HbA1c decreased from (median (IQR)) 9.9 (8.8, 11.2)%; 85 (73, 99) mmol/mol to 7.3 (6.9, 7.8)%; 56 (52, 62) mmol/mol at 24 weeks (p < 0.0001). Comparing r-CGM (n = 46) with SMBG (n = 42), there were no differences in major hypoglycaemia (p=0.17) or ΔHbA1c (p = 0.31). More r-CGM than SMBG participants commenced glulisine (26/48 vs. 7/44; p < 0.001). Results were comparable to 82 benchmark patients, with similar low rates of major hypoglycaemia (2/89 vs. 0/82; p = 0.17) and less loss to follow up in the INITIATION group (3/92 vs. 14/82; p = 0.002). Insulin initiation and titration for T2DM patients in primary care was safe and improved HbA1c with low rates of major hypoglycaemia. CDE-RNs were effective in a new consultant role. r-CGM use in primary care was feasible and enhanced post-prandial hyperglycaemia recognition. Trial registration ACTRN12610000797077. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  11. Monitoring system for gamma radiation of porch type for vehicles

    International Nuclear Information System (INIS)

    Vazquez C, R.M.; Molina, G.; Gutierrez O, E.; Ramirez J, F.J.; Garcia H, J.M.; Aguilar B, M.A.; Vilchis P, A.E.; Cruz E, P.; Torres B, M.A.

    2005-01-01

    A monitoring system of gamma radiation for vehicles of the porch type developed in the ININ is presented. This system carries out the radiological monitoring of the vehicles in continuous form, detecting the bottom radiological environment and the presence of nuclear material transported in vehicles. The vehicles are monitored while they pass to low speed through the porch. The detectors are plastic scintillators of great volume that allow high sensibility detection. The arrangement of detecting is interconnected in net, and the data are concentrated on a personal computer whose interface man-machine can be accessed from any personal computer connected to Internet. The system monitoring in real time with options of sampling times from 50 ms configurable up to 500 ms. (Author)

  12. Clinical use of continuous glucose monitoring in adults with type 1 diabetes

    OpenAIRE

    Slattery, David; Choudhary, Pratik

    2017-01-01

    With the emphasis on intensive management of type 1 diabetes, data from studies support frequent monitoring of glucose levels to improve glycemic control and reduce glucose variability, which can be related to an increase in macro and microvascular complications. However, few perform capillary blood glucose that frequently. There are currently two available alternatives that this review will discuss, continuous glucose monitoring (CGM) and flash glucose monitoring. CGM has become an important...

  13. Wireless patient monitoring system for a moving-actuator type artificial heart.

    Science.gov (United States)

    Nam, K W; Chung, J; Choi, S W; Sun, K; Min, B G

    2006-10-01

    In this study, we developed a wireless monitoring system for outpatients equipped with a moving-actuator type pulsatile bi-ventricular assist device, AnyHeart. The developed monitoring system consists of two parts; a Bluetooth-based short-distance self-monitoring system that can monitor and control the operating status of a VAD using a Bluetooth-embedded personal digital assistant or a personal computer within a distance of 10 meters, and a cellular network-based remote monitoring system that can continuously monitor and control the operating status of AnyHeart at any location. Results of in vitro experiments demonstrate the developed system's ability to monitor the operational status of an implanted AnyHeart.

  14. [Explicit memory for type font of words in source monitoring and recognition tasks].

    Science.gov (United States)

    Hatanaka, Yoshiko; Fujita, Tetsuya

    2004-02-01

    We investigated whether people can consciously remember type fonts of words by methods of examining explicit memory; source-monitoring and old/new-recognition. We set matched, non-matched, and non-studied conditions between the study and the test words using two kinds of type fonts; Gothic and MARU. After studying words in one way of encoding, semantic or physical, subjects in a source-monitoring task made a three way discrimination between new words, Gothic words, and MARU words (Exp. 1). Subjects in an old/new-recognition task indicated whether test words were previously presented or not (Exp. 2). We compared the source judgments with old/new recognition data. As a result, these data showed conscious recollection for type font of words on the source monitoring task and dissociation between source monitoring and old/new recognition performance.

  15. Structural Health Monitoring for a Z-Type Special Vehicle

    Directory of Open Access Journals (Sweden)

    Chaolin Yuan

    2017-06-01

    Full Text Available Nowadays there exist various kinds of special vehicles designed for some purposes, which are different from regular vehicles in overall dimension and design. In that case, accidents such as overturning will lead to large economical loss and casualties. There are still no technical specifications to follow to ensure the safe operation and driving of these special vehicles. Owing to the poor efficiency of regular maintenance, it is more feasible and effective to apply real-time monitoring during the operation and driving process. In this paper, the fiber Bragg grating (FBG sensors are used to monitor the safety of a z-type special vehicle. Based on the structural features and force distribution, a reasonable structural health monitoring (SHM scheme is presented. Comparing the monitoring results with the finite element simulation results guarantees the accuracy and reliability of the monitoring results. Large amounts of data are collected during the operation and driving progress to evaluate the structural safety condition and provide reference for SHM systems developed for other special vehicles.

  16. Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment

    Science.gov (United States)

    Vandersluis, Stacey; Kabali, Conrad; Djalalov, Sandjar; Gajic-Veljanoski, Olga; Wells, David; Holubowich, Corinne

    2018-01-01

    Background Type 1 diabetes is a condition in which the pancreas produces little or no insulin. People with type 1 diabetes must manage their blood glucose levels by monitoring the amount of glucose in their blood and administering appropriate amounts of insulin via injection or an insulin pump. Continuous glucose monitoring may be beneficial compared to self-monitoring of blood glucose using a blood glucose meter. It provides insight into a person's blood glucose levels on a continuous basis, and can identify whether blood glucose levels are trending up or down. Methods We conducted a health technology assessment, which included an evaluation of clinical benefit, value for money, and patient preferences related to continuous glucose monitoring. We compared continuous glucose monitoring with self-monitoring of blood glucose using a finger-prick and a blood glucose meter. We performed a systematic literature search for studies published since January 1, 2010. We created a Markov model projecting the lifetime horizon of adults with type 1 diabetes, and performed a budget impact analysis from the perspective of the health care payer. We also conducted interviews and focus group discussions with people who self-manage their type 1 diabetes or support the management of a child with type 1 diabetes. Results Twenty studies were included in the clinical evidence review. Compared with self-monitoring of blood glucose, continuous glucose monitoring improved the percentage of time patients spent in the target glycemic range by 9.6% (95% confidence interval 8.0–11.2) to 10.0% (95% confidence interval 6.75–13.25) and decreased the number of severe hypoglycemic events. Continuous glucose monitoring was associated with higher costs and small increases in health benefits (quality-adjusted life-years). Incremental cost-effectiveness ratios (ICERs) ranged from $592,206 to $1,108,812 per quality-adjusted life-year gained in analyses comparing four continuous glucose monitoring

  17. Continuous Monitoring of Glucose for Type 1 Diabetes: A Health Technology Assessment.

    Science.gov (United States)

    2018-01-01

    Type 1 diabetes is a condition in which the pancreas produces little or no insulin. People with type 1 diabetes must manage their blood glucose levels by monitoring the amount of glucose in their blood and administering appropriate amounts of insulin via injection or an insulin pump. Continuous glucose monitoring may be beneficial compared to self-monitoring of blood glucose using a blood glucose meter. It provides insight into a person's blood glucose levels on a continuous basis, and can identify whether blood glucose levels are trending up or down. We conducted a health technology assessment, which included an evaluation of clinical benefit, value for money, and patient preferences related to continuous glucose monitoring. We compared continuous glucose monitoring with self-monitoring of blood glucose using a finger-prick and a blood glucose meter. We performed a systematic literature search for studies published since January 1, 2010. We created a Markov model projecting the lifetime horizon of adults with type 1 diabetes, and performed a budget impact analysis from the perspective of the health care payer. We also conducted interviews and focus group discussions with people who self-manage their type 1 diabetes or support the management of a child with type 1 diabetes. Twenty studies were included in the clinical evidence review. Compared with self-monitoring of blood glucose, continuous glucose monitoring improved the percentage of time patients spent in the target glycemic range by 9.6% (95% confidence interval 8.0-11.2) to 10.0% (95% confidence interval 6.75-13.25) and decreased the number of severe hypoglycemic events.Continuous glucose monitoring was associated with higher costs and small increases in health benefits (quality-adjusted life-years). Incremental cost-effectiveness ratios (ICERs) ranged from $592,206 to $1,108,812 per quality-adjusted life-year gained in analyses comparing four continuous glucose monitoring interventions to usual care

  18. Unexpected properties of Radim-type radon monitors

    International Nuclear Information System (INIS)

    Plch, J.; Burian, I.; Jilek, K.; Vosahlik, J.

    2004-01-01

    The results of numerous experiments carried out using Radim-type monitors are summarized. The monitor, which is based on collection of ions on the surface of a semiconductor detector in an electric field, exhibits enormous efficiency in collecting ions, which attains a value of 70% in the optimum case. The collection efficiency exhibits low dependence on the humidity: the efficiency decreases by 7.4% when the humidity changes from 50 to 90%. The dependence on the humidity is linear to 10% - in contradiction with the published results. The work gives the experimentally determined decreases in the presence of smoke and VOCs, which are acceptable even when the smoke and VOC concentrations are enormous. The results are analyzed and an attempt was made to theoretically explain these unexpected results. (author)

  19. A new type of spurious reading in TL personnel monitoring

    International Nuclear Information System (INIS)

    Duftschmid, K.E.; Stadtmann, H.; Strachotinsky, Ch.; Winker, N.

    1996-01-01

    A particularly serious type of spurious reading in automated TL personnel monitoring has been observed. These readings simulate dose values up to several mSv and can only be detected by glow curve analysis. Characteristics for these events are high artifical dose values and irregular glow curves of a particular shape. Extensive investigations to reproduce this effect purposely failed to produce any results. It can be assumed, however, that it must be some chemical surface contamination, which penetrates the sealed dosemeter bag or which is transferred from the bag to the detector. The effect can be eliminated by manual cleaning of the dosemeter cards. The importance of this observation lies in the fact that only proper glow curve evaluation can prevent the monitoring service from reporting artificial high dose readings creating lots of serious problems. The paper shows how this problem can be avoided for this kind of spurious effect, if glow curves are available and stored for every dosemeter readout. (author)

  20. The use and efficacy of continuous glucose monitoring in type 1 diabetes treated with insulin pump therapy

    DEFF Research Database (Denmark)

    Battelino, T; Conget, I; Olsen, B

    2012-01-01

    The aim of this multicentre, randomised, controlled crossover study was to determine the efficacy of adding continuous glucose monitoring (CGM) to insulin pump therapy (CSII) in type 1 diabetes.......The aim of this multicentre, randomised, controlled crossover study was to determine the efficacy of adding continuous glucose monitoring (CGM) to insulin pump therapy (CSII) in type 1 diabetes....

  1. Neutron dosimetry. Environmental monitoring in a BWR type reactor

    International Nuclear Information System (INIS)

    Tavera D, L.; Camacho L, M.E.

    1991-01-01

    The measurements carried out on reactor dosimetry are applied mainly to the study on the effects of the radiation in 108 materials of the reactor; little is on the environmental dosimetry outside of the primary container of BWR reactors. In this work the application of a neutron spectrometer formed by plastic detectors of nuclear traces manufactured in the ININ, for the environmental monitoring in penetrations around the primary container of the unit I of the Laguna Verde central is presented. The neutron monitoring carries out with purposes of radiological protection, during the operational tests of the reactor. (Author)

  2. Integrating working level monitor EML Type TF-11

    International Nuclear Information System (INIS)

    Latner, N.; Watnick, S.; Graveson, R.T.

    1981-01-01

    A time-integrating working level radiation monitor is described. The purpose of the instrument is the evaluation of the alpha emission from radon and its daughter products. It has been designed to be virtually silent in operation, making it suitable for residential studies

  3. Intraesophageal impedance monitoring: clinical studies

    NARCIS (Netherlands)

    Conchillo Armendáriz, J.M.

    2007-01-01

    Electrical impedance (Z) between two electrodes is the ratio between applied voltage (U) and resulting current (I). In electrical impedance monitoring the resistance to electrical flow in an alternating current circuit is measured. Multichannel esophageal monitoring can be measured by using an

  4. Response comparative study of Rn-222 alpha particles track monitors

    International Nuclear Information System (INIS)

    Pereira, Osvaldo Luiz dos Santos

    2010-01-01

    This work was a comparative study between the responses of three monitors, the NRPB, an acrylic monitor (in thin film geometry) and the aluminum monitor (also thin film geometry) in controlled and mixed environment. The experiments consisted on placing the monitors in a plastic tube, with a radio-226 source internal. Only internal CR-39 plastic detectors were analyzed in this work. It was found that the monitors in thin film geometry had activities response of approximately 15% less than the NRPB monitors. All monitors responded the same way when in controlled environment. Related to the type of material, conductive plastic or dielectric (insulator) plastic, the NRPB, in environments without ventilation, responded in the same way. (author)

  5. Salivary glucose in monitoring glycaemia in patients with type 1 diabetes mellitus: a systematic review.

    Science.gov (United States)

    Naing, Cho; Mak, Joon Wah

    2017-01-01

    Incidence of type 1 diabetes mellitus is increasing worldwide. Monitoring glycaemia is essential for control of diabetes mellitus. Conventional blood-based measurement of glucose requires venepuncture or needle prick, which is not free from pain and risk of infection. The non-invasiveness, ease and low-cost in collection made saliva an attractive alternative sample. The objective of this review was to systematically review the evidence on the relationship between salivary glucose level and blood glucose level in monitoring glycaemia in patients with type 1 diabetes mellitus. We searched studies which evaluate salivary glucose levels and serum glycaemia in type 1 diabetes mellitus in electronic databases of MEDLINE, EMBASE, Ovid and Google Scholar. We selected the eligible studies, following the inclusion criteria set for this review. Due to heterogeneity of studies, we conducted qualitative synthesis of studies. Ten observational studies were included in this review, including a total of 321 cases and 323 controls with ages between 3 and 61 years and the majority were males (62%). Two studies were done exclusively on children below 17 years old. The significant difference between salivary glucose levels in type 1 diabetes mellitus and controls were reported in 6 studies with 8 data sets. Five studies with 7 datasets reported the correlation coefficient between salivary glucose and blood glucose in patients with diabetes. Findings suggest that salivary glucose concentrations may be helpful in monitoring glycaemia in type 1 diabetes mellitus. However, the utility of using salivary glucose level to monitor glycaemia should be evaluated in future well designed, prospective studies with adequate number of participants with type 1 diabetes mellitus.

  6. Low cost sensing technology for type 2 diabetes monitoring

    Science.gov (United States)

    Sarswat, Prashant; Free, Michael

    2015-03-01

    Alpha-hydroxybutyrate (2-hydroxybutyrate or α-HB) is becoming more widely recognized as an important metabolic biomarker that has been shown to be highly correlated with prediabetes and other metabolic diseases. In 2012 there were 86 million Americans with prediabetes, many of whom are not aware they have prediabetes, but could be diagnosed and treated to prevent type 2 diabetes if a simple, low-cost, convenient test were available. We have developed new, low-cost, accurate α-HB detection methods that can be used for the detection and monitoring of diseases such as prediabetes, type 2 diabetes, β-cell dysfunction, and early hyperglycemia. The new sensing method utilizes a diol recognition moiety, additives and a photoinitiator to detect α-HB at levels near 1 micro g/l in the presence of serum compounds such as lactic acid, sodium pyruvate, and glucose. The objective of this research is to improve the understanding of the interactions that enhance α-HB detection to enable additional improvements in α-HB detection as well as improvements in other biosensor applications.

  7. Stitching Type Large Aperture Depolarizer for Gas Monitoring Imaging Spectrometer

    Science.gov (United States)

    Liu, X.; Li, M.; An, N.; Zhang, T.; Cao, G.; Cheng, S.

    2018-04-01

    To increase the accuracy of radiation measurement for gas monitoring imaging spectrometer, it is necessary to achieve high levels of depolarization of the incoming beam. The preferred method in space instrument is to introduce the depolarizer into the optical system. It is a combination device of birefringence crystal wedges. Limited to the actual diameter of the crystal, the traditional depolarizer cannot be used in the large aperture imaging spectrometer (greater than 100 mm). In this paper, a stitching type depolarizer is presented. The design theory and numerical calculation model for dual babinet depolarizer were built. As required radiometric accuracies of the imaging spectrometer with 250 mm × 46 mm aperture, a stitching type dual babinet depolarizer was design in detail. Based on designing the optimum structural parmeters the tolerance of wedge angle refractive index, and central thickness were given. The analysis results show that the maximum residual polarization degree of output light from depolarizer is less than 2 %. The design requirements of polarization sensitivity is satisfied.

  8. STITCHING TYPE LARGE APERTURE DEPOLARIZER FOR GAS MONITORING IMAGING SPECTROMETER

    Directory of Open Access Journals (Sweden)

    X. Liu

    2018-04-01

    Full Text Available To increase the accuracy of radiation measurement for gas monitoring imaging spectrometer, it is necessary to achieve high levels of depolarization of the incoming beam. The preferred method in space instrument is to introduce the depolarizer into the optical system. It is a combination device of birefringence crystal wedges. Limited to the actual diameter of the crystal, the traditional depolarizer cannot be used in the large aperture imaging spectrometer (greater than 100 mm. In this paper, a stitching type depolarizer is presented. The design theory and numerical calculation model for dual babinet depolarizer were built. As required radiometric accuracies of the imaging spectrometer with 250 mm × 46 mm aperture, a stitching type dual babinet depolarizer was design in detail. Based on designing the optimum structural parmeters,the tolerance of wedge angle,refractive index, and central thickness were given. The analysis results show that the maximum residual polarization degree of output light from depolarizer is less than 2 %. The design requirements of polarization sensitivity is satisfied.

  9. Type studies in Basidiomycetes. X

    NARCIS (Netherlands)

    Singer, R.

    1961-01-01

    For the first time a systematic study of the types and authentic specimens of agarics and boletes preserved in the Persoon Herbarium has been carried out. Some aspects of the possibilities of type analysis with regard to specimens over 130 year old are discussed. 137 species were analyzed. The

  10. Severe hypoglycemia, impaired awareness of hypoglycemia, and self-monitoring in adults with type 1 diabetes

    DEFF Research Database (Denmark)

    Hendrieckx, Crystal; Jenkins, A; Hagger, Virginia

    2017-01-01

    AIMS: To assess prevalence of severe hypoglycemia, awareness and symptoms of hypoglycemia, and their associations with self-monitoring of blood glucose. METHODS: Diabetes MILES-Australia Study participants completed validated questionnaires and study-specific items. RESULTS: Of 642 adults with ty...... autonomic symptoms, perceived at relatively low glucose levels. Frequent self-monitoring of blood glucose prompted early recognition and treatment of hypoglycemia, suggesting severe hypoglycemia risk can be minimized.......AIMS: To assess prevalence of severe hypoglycemia, awareness and symptoms of hypoglycemia, and their associations with self-monitoring of blood glucose. METHODS: Diabetes MILES-Australia Study participants completed validated questionnaires and study-specific items. RESULTS: Of 642 adults with type...

  11. A new type gamma-ray spectrum monitoring system

    CERN Document Server

    Cheng Bo; Zhou Jian Bin; Zhang Zhi Ming; Tong Yun Fu

    2002-01-01

    This new radiation monitoring system can be used to monitor the radiation of building materials and the radiation of atmosphere, to explore and evaluate rock for building in the field, and this system can be used to monitor the gamma irradiation near the nuclear establishments in the average situation and in the serious situation of the radiation incident have happened. The control core of this monitoring system is SCM-AT89C52, and gamma-ray sensing head consists of scintillator phi 50 mm x 50 mm NaI(Tl) and PMT GDB44. This system can be used to measure the whole gamma-ray spectrum of 256 channels

  12. A 12-week pilot study of acceptance of a computer-based chronic disease self-monitoring system among patients with type 2 diabetes mellitus and/or hypertension.

    Science.gov (United States)

    Yan, Mian; Or, Calvin

    2017-08-01

    This study tested a structural model examining the effects of perceived usefulness, perceived ease of use, attitude, subjective norm, perceived behavioral control, health consciousness, and application-specific self-efficacy on the acceptance (i.e. behavioral intention and actual usage) of a computer-based chronic disease self-monitoring system among patients with type 2 diabetes mellitus and/or hypertension. The model was tested using partial least squares structural equation modeling, with 119 observations that were obtained by pooling data across three time points over a 12-week period. The results indicate that all of the seven constructs examined had a significant total effect on behavioral intention and explained 74 percent of the variance. Also, application-specific self-efficacy and behavioral intention had a significant total effect on actual usage and explained 17 percent of the variance. This study demonstrates that technology acceptance is determined by patient characteristics, technology attributes, and social influences. Applying the findings may increase the likelihood of acceptance.

  13. Experimental studies of minienvironment types

    International Nuclear Information System (INIS)

    Eissler, W.; Schneider, H.

    1994-01-01

    Various minienvironment types are available offering different features at quite different costs. MEISSNER+WURST performed in its JESSI project experimental tests to examine the isolation capabilities and the recovery time of minienvironments and the influence of manual handling and maintenance on the minienvironment cleanliness. An isolation factor up to 1 million was measured in the experiments. The Custom Tailored Minienvironment has the best protection against external and internal particle sources. Critical points in the design and the installation of minienvironments were identified. The results of air flow visualization studies were confirmed by airflow simulations. The result of the studies allow a classification of minienvironment types according to their cleanliness achievements

  14. Effectiveness and cost-effectiveness of serum B-type natriuretic peptide testing and monitoring in patients with heart failure in primary and secondary care: an evidence synthesis, cohort study and cost-effectiveness model.

    Science.gov (United States)

    Pufulete, Maria; Maishman, Rachel; Dabner, Lucy; Mohiuddin, Syed; Hollingworth, William; Rogers, Chris A; Higgins, Julian; Dayer, Mark; Macleod, John; Purdy, Sarah; McDonagh, Theresa; Nightingale, Angus; Williams, Rachael; Reeves, Barnaby C

    2017-08-01

    Heart failure (HF) affects around 500,000 people in the UK. HF medications are frequently underprescribed and B-type natriuretic peptide (BNP)-guided therapy may help to optimise treatment. To evaluate the clinical effectiveness and cost-effectiveness of BNP-guided therapy compared with symptom-guided therapy in HF patients. Systematic review, cohort study and cost-effectiveness model. A literature review and usual care in the NHS. (a) HF patients in randomised controlled trials (RCTs) of BNP-guided therapy; and (b) patients having usual care for HF in the NHS. Systematic review : BNP-guided therapy or symptom-guided therapy in primary or secondary care. Cohort study : BNP monitored (≥ 6 months' follow-up and three or more BNP tests and two or more tests per year), BNP tested (≥ 1 tests but not BNP monitored) or never tested. Cost-effectiveness model : BNP-guided therapy in specialist clinics. Mortality, hospital admission (all cause and HF related) and adverse events; and quality-adjusted life-years (QALYs) for the cost-effectiveness model. Systematic review : Individual participant or aggregate data from eligible RCTs. Cohort study : The Clinical Practice Research Datalink, Hospital Episode Statistics and National Heart Failure Audit (NHFA). A systematic literature search (five databases, trial registries, grey literature and reference lists of publications) for published and unpublished RCTs. Five RCTs contributed individual participant data (IPD) and eight RCTs contributed aggregate data (1536 participants were randomised to BNP-guided therapy and 1538 participants were randomised to symptom-guided therapy). For all-cause mortality, the hazard ratio (HR) for BNP-guided therapy was 0.87 [95% confidence interval (CI) 0.73 to 1.04]. Patients who were aged Chris A Rogers' and Maria Pufulete's time contributing to the study. Syed Mohiuddin's time is supported by the NIHR Collaboration for Leadership in Applied Health Research and Care West at University

  15. BH2201 type leakage monitoring equipment of reactor fuel elements

    International Nuclear Information System (INIS)

    Ji Changsong; Dai Zhude; Xie Liangnian; Zhang Shulan; Zhang Shuheng

    1999-01-01

    A high-sensitive equipment monitoring leakage of the reactor fuel elements has been developed. The delayed neutrons emitted from fission product-pioneer nucleus are monitored in the 1st circle water. An array of 3 He proportional counter tubes is designed as a neutron detector for delayed neutrons, the detection geometry of which is near to 4π. In order to reduce the influence of interference factors the monitoring of fission product is carried out with 75s delay. The 87 Br delayed neutron pioneer nucleus is chosen as a monitoring object. The neutron detection efficiency of the developed equipment is 6.1%, which is 3 times higher than one of all available advanced equipment of the same function both at home and abroad

  16. Study of personnel monitoring programs

    International Nuclear Information System (INIS)

    Guerra, Aline B.; Lorenzini, Fabiane; Carlos, Janaina; Bernasiuk, Maria E.B.; Rizzatti, Mara R.; Fuentefria, Jose L.B.

    1996-01-01

    Surveillance of several health institutions who use ionizing radiation sources, as well as data from the state of Rio Grande do Sul (Brazil) are studied concerning the use of personnel dosimeters. The results show that several institutions do not provide them and those which provide do not know how to use them

  17. Environmental monitoring systems: a new type of mobile laboratory

    International Nuclear Information System (INIS)

    Bruecher, L.; Langmueller, G.; Tuerschmann, G.

    1999-01-01

    Nuclear facilities are obligated to monitor the environmental radiation in their vicinity, which is often fulfilled by monitoring cars, combined with fixed monitoring stations. The MOLAR Mobile Laboratory for Environmental Radiation Monitoring as described here is being used under normal and accident conditions as a spot check monitoring system or to perform continuous measurements along a driving track. The mobile laboratories are continuously connected with the control centre's CRCS Central Radiological Computer System, where the RIS Radiological Information System provides corresponding evaluation functions. The mobile labs contain measuring and controlling units like γ-dose rate monitors, γ-spectrometer with a HpGe High Purity Germanium detector, a lead shielded measuring cell and MCA Multi-Channel Analyser, portable β-contamination monitor, α/β/γ multipurpose quick measuring unit, aerosol and iodine sampling units. The collected samples are safely stored for the transport to the environmental laboratory for being analysed later. The geographical location of the moving car is continuously determined by the satellite based GPS Global Positioning System and transferred in the on-board rack mounted computer system for being stored and locally displayed. Real-time data transmission via radio and mobile phone is continuously performed to supply the RIS Radiological Information System in the control centre via radio and mobile phone. The latter also serves for voice communication. Currently three MOLAR systems can be operated parallel and independent from the control centre. The system is ready to be extended to more mobile labs. This combination of mobile monitoring, sample analysis and radiological assessment of environmental data in combination with process occurrences has turned out to be a powerful instrument for emergency preparedness and environmental supervising. (orig.) [de

  18. Clinical Use of Continuous Glucose Monitoring in Adults with Type 1 Diabetes.

    Science.gov (United States)

    Slattery, David; Choudhary, Pratik

    2017-05-01

    With the emphasis on intensive management of type 1 diabetes, data from studies support frequent monitoring of glucose levels to improve glycemic control and reduce glucose variability, which can be related to an increase in macro and microvascular complications. However, few perform capillary blood glucose that frequently. There are currently two available alternatives that this review will discuss, continuous glucose monitoring (CGM) and flash glucose monitoring. CGM has become an important diagnostic and therapeutic option in optimizing diabetes management. CGM systems are now more accurate, smaller, and easier to use compared to original models. Randomized controlled trials (RCTs) have demonstrated that CGM can improve Hemoglobin A1c (HbA1C) and reduce glucose variability in both continuous subcutaneous insulin infusion and multiple daily injection users. When used in an automated "insulin-suspend" system, reduced frequency of hypoglycemia and shorter time spent in hypoglycemic range have been demonstrated. Despite the potential benefits CGM has to offer in clinical practice, concerns exist on the accuracy of these devices and patient compliance with therapy, which may prevent the true clinical benefit of CGM being achieved, as observed in RCTs. Flash glucose monitoring systems FreeStyle ® Libre™ (Abbott Diabetes Care, Alameda, CA) are as accurate as many CGM systems available and have the added benefit of being factory calibrated. Studies have shown that flash glucose monitoring systems are very well tolerated by patients and effectively reduce glucose variability, increasing time in range.

  19. Moisture monitoring and control system engineering study

    International Nuclear Information System (INIS)

    Carpenter, K.E.; Fadeff, J.G.

    1995-01-01

    During the past 50 years, a wide variety of chemical compounds have been placed in the 149 single-shell tanks (SSTS) on the Hanford Site. A concern relating to chemical stability, chemical control, and safe storage of the waste is the potential for propagating reactions as a result of ferrocyanide-oxidizer and organic-oxidizer concentrations in the SSTS. Propagating reactions in fuel-nitrate mixtures are precluded if the amounts of fuel and moisture present in the waste are within specified limits. Because most credible ignition sources occur near the waste surface, the main emphasis of this study is toward monitoring and controlling moisture in the top 14 cm (5.5 in.) of waste. The purpose of this engineering study is to recommend a moisture monitoring and control system for use in SSTs containing sludge and saltcake. This study includes recommendations for: (1) monitoring and controlling moisture in SSTs; (2) the fundamental design criteria for a moisture monitoring and control system; and (3) criteria for the deployment of a moisture monitoring and control system in hanford Site SSTs. To support system recommendations, technical bases for selecting and using a moisture monitoring and control system are presented. Key functional requirements and a conceptual design are included to enhance system development and establish design criteria

  20. False alarm reduction in BSN-based cardiac monitoring using signal quality and activity type information.

    Science.gov (United States)

    Tanantong, Tanatorn; Nantajeewarawat, Ekawit; Thiemjarus, Surapa

    2015-02-09

    False alarms in cardiac monitoring affect the quality of medical care, impacting on both patients and healthcare providers. In continuous cardiac monitoring using wireless Body Sensor Networks (BSNs), the quality of ECG signals can be deteriorated owing to several factors, e.g., noises, low battery power, and network transmission problems, often resulting in high false alarm rates. In addition, body movements occurring from activities of daily living (ADLs) can also create false alarms. This paper presents a two-phase framework for false arrhythmia alarm reduction in continuous cardiac monitoring, using signals from an ECG sensor and a 3D accelerometer. In the first phase, classification models constructed using machine learning algorithms are used for labeling input signals. ECG signals are labeled with heartbeat types and signal quality levels, while 3D acceleration signals are labeled with ADL types. In the second phase, a rule-based expert system is used for combining classification results in order to determine whether arrhythmia alarms should be accepted or suppressed. The proposed framework was validated on datasets acquired using BSNs and the MIT-BIH arrhythmia database. For the BSN dataset, acceleration and ECG signals were collected from 10 young and 10 elderly subjects while they were performing ADLs. The framework reduced the false alarm rate from 9.58% to 1.43% in our experimental study, showing that it can potentially assist physicians in diagnosing a vast amount of data acquired from wireless sensors and enhance the performance of continuous cardiac monitoring.

  1. False Alarm Reduction in BSN-Based Cardiac Monitoring Using Signal Quality and Activity Type Information

    Directory of Open Access Journals (Sweden)

    Tanatorn Tanantong

    2015-02-01

    Full Text Available False alarms in cardiac monitoring affect the quality of medical care, impacting on both patients and healthcare providers. In continuous cardiac monitoring using wireless Body Sensor Networks (BSNs, the quality of ECG signals can be deteriorated owing to several factors, e.g., noises, low battery power, and network transmission problems, often resulting in high false alarm rates. In addition, body movements occurring from activities of daily living (ADLs can also create false alarms. This paper presents a two-phase framework for false arrhythmia alarm reduction in continuous cardiac monitoring, using signals from an ECG sensor and a 3D accelerometer. In the first phase, classification models constructed using machine learning algorithms are used for labeling input signals. ECG signals are labeled with heartbeat types and signal quality levels, while 3D acceleration signals are labeled with ADL types. In the second phase, a rule-based expert system is used for combining classification results in order to determine whether arrhythmia alarms should be accepted or suppressed. The proposed framework was validated on datasets acquired using BSNs and the MIT-BIH arrhythmia database. For the BSN dataset, acceleration and ECG signals were collected from 10 young and 10 elderly subjects while they were performing ADLs. The framework reduced the false alarm rate from 9.58% to 1.43% in our experimental study, showing that it can potentially assist physicians in diagnosing a vast amount of data acquired from wireless sensors and enhance the performance of continuous cardiac monitoring.

  2. Use of self-monitoring tools in a clinic sample of adults with type 2 diabetes.

    Science.gov (United States)

    Tanenbaum, Molly L; Bhatt, Harikrashna B; Thomas, Valerie A; Wing, Rena R

    2017-06-01

    Self-monitoring is an effective strategy for chronic disease management; many readily available mobile applications allow tracking of diabetes-related health behaviors but their use has not yet been integrated into routine clinical care. How patients engage with these applications in the real world is not well understood. The specific aim of this study is to survey adults with type 2 diabetes (T2D) regarding self-monitoring behaviors, including mobile application use. In 2015, we surveyed an adult diabetes clinic population (n = 96) regarding self-monitoring behaviors: diet, physical activity, weight, and blood glucose. Self-monitoring with any method ranged from 20-90 %. About half of the participants owned smartphones; few had mobile applications. The most common app-tracked behavior was physical activity, then weight and diet. Despite numerous available mobile health-tracking applications, few T2D adults from our sample used them, though many reported self-monitoring with other methods.

  3. Effect of prandial treatment timing adjustment, based on continuous glucose monitoring, in patients with type 2 diabetes uncontrolled with once-daily basal insulin: A randomized, phase IV study.

    Science.gov (United States)

    Ilany, Jacob; Bhandari, Hamad; Nabriski, Dan; Toledano, Yoel; Konvalina, Noa; Cohen, Ohad

    2018-05-01

    To evaluate the glycaemic control achieved by prandial once-daily insulin glulisine injection timing adjustment, based on a continuous glucose monitoring sensor, in comparison to once-daily insulin glulisine injection before breakfast in patients with type 2 diabetes who are uncontrolled with once-daily basal insulin glargine. This was a 24-week open-label, randomized, controlled, multicentre trial. At the end of an 8-week period of basal insulin optimization, patients with HbA1c ≥ 7.5% and FPG sensor) or arm B (sensor) to receive 16-week intensified prandial glulisine treatment. Patients in arm A received pre-breakfast glulisine, and patients in arm B received glulisine before the meal with the highest glucose elevation based on sensor data. The primary outcome was mean HbA1c at week 24 and secondary outcomes included rates of hypoglycaemic events and insulin dosage. A total of 121 patients were randomized to arm A (n = 61) or arm B (n = 60). There was no difference in mean HbA1c at week 24 between arms A and B (8.5% ± 1.2% vs 8.4% ± 1.0%; P = .66). The prandial insulin glulisine dosage for arm A and arm B was 9.3 and 10.1 units, respectively (P = .39). The frequency of hypoglycaemic events did not differ between study arms (36.1% vs 51.7%; P = .08). Using a CGM sensor to identify the meal with the highest glucose excursion and adjusting the timing of prandial insulin treatment did not show any advantage in terms of glycaemic control or safety in our patients. © 2018 The Authors. Diabetes, Obesity and Metabolism published by John Wiley & Sons Ltd.

  4. Type of equipment in an air monitoring station

    International Nuclear Information System (INIS)

    Levy, F.

    1999-01-01

    This poster communication presents a general view of the station, the different materials used for the air and precipitations monitoring. The methods for gas measurements (tritium, krypton, iodine) are given. The collecting of dusts, dust and tritium mixed together, or rainwater and pluviometry are reviewed and the measurement of ambient radioactivity is made by beacon. (N.C.)

  5. Memory-type control charts for monitoring the process dispersion

    NARCIS (Netherlands)

    Abbas, N.; Riaz, M.; Does, R.J.M.M.

    2014-01-01

    Control charts have been broadly used for monitoring the process mean and dispersion. Cumulative sum (CUSUM) and exponentially weighted moving average (EWMA) control charts are memory control charts as they utilize the past information in setting up the control structure. This makes CUSUM and

  6. Identification of process dynamics. Stability monitoring in BWR type reactors

    International Nuclear Information System (INIS)

    Abrahamsson, P.; Hallgren, P.

    1991-06-01

    Identification of process dynamics is used for stability monitoring in nuclear reactors (Boiling Water Reactor). This report treats the problem of estimating a damping factor and a resonance frequency from the neutron flux as measured in the reactor. A new parametric online method for identification is derived and presented, and is shown to meet the requirements of stability monitoring. The technique for estimating the process parameters is based on a recursive lattice filter algorithm. The problem of time varying parameters and offset, as well as offline experiments and signal processing are treated. All parts are implemented in a realtime program, using the language C. In comparison with earlier identifications, the new way of estimating the damping factor is shown to work well. Estimates of both the damping factor and the resonance frequency show a stable and reliable behavior. Future development and improvements are also indicated. (au)

  7. Radiological assessments, environmental monitoring, and study design

    International Nuclear Information System (INIS)

    Hansen, W.R.; Elle, D.R.

    1980-01-01

    Studies of the behavior of transuranic elements in the environment form the basic data for applied programs in radiological assessment, environmental monitoring, derivation of radiation-protection standards, and environmental impact statements. This chapter introduces some of the major information requirements of these applications of transuranic research data. Characteristics of the source terms from nuclear activities usually are needed for an analysis of environmental pathways or deployment of monitoring systems. Major inhalation and ingestion pathways are considered in assessments of hazards from transuranics and are discussed from the viewpoint of research needed

  8. [Usefulness of continuous glucose monitoring system (CGMS) in monitoring glycaemic profile in small children with diabetes type 1].

    Science.gov (United States)

    Głowińska-Olszewska, Barbara; Urban, Mirosława; Peczyńska, Jadwiga; Florys, Bozena; Kowalewski, Marek

    2005-01-01

    Improved methods of diabetes therapy result in a near normoglycaemic state in many patients. This leads however unfortunately to more frequent hypoglycaemic incidents. Particularly small children, whose nervous system is not fully mature, are at high risk of central nervous system damage in case of hypoglycaemia. A new method of detail monitoring of glycaemia provides CGMS system. The aim of the study was to compare the glycaemic profile, with high attention to hypoglycaemia in groups of young and older children with diabetes type 1, using CGMS and routine glucose meter. We studied 32 children with diabetes type 1. Children were divided into groups: group I--small children, n=17 (10 years of age), mean age--12 years, with disease duration--3 years, with HbA1c level--7,21%. Continuous glucose monitoring system (CGMS), by MiniMed, was applied in outpatient or hospital conditions, after short training of patient and parents; together with routine glucose meter measurements, 4-8 times/24 hours. In 9 patients from small children group CGMS was repeated after 2 months. Hypoglycaemic incidents detected with CGMS were similar in both groups: 4,6 in I group vs. 4,2 in II group (ns). Hypoglycaemic incidents found with meter were lower in I group--1,6 vs. 2,3 in II group (ns). Mean hypoglycaemic time/24 hour was longer in small children group: 101 min vs. 74 min in group II (p<00,05). In I group we found higher number of hypoglycaemic incidents during the night compared to group II--1,7 vs. 0,8 (p<00,05) and longer duration of night hypoglycaemia: in I group--56 min vs. 32 min in group II (p<00,05). Repeated CGMS study in 9 children from I group revealed decreased mean time of hypoglycaemia/24 hours from 134 min/24 h to 90 min/24 h (p<00,05) and decreased time of night hypoglycaemia from 65 min to 40 min (p<00,05), with a comparable number of hypoglycaemic incidents. Hypoglycaemic incidents found with routine meter measurements in small children were 1,6 vs. 4,6 hypoglycaemia

  9. Study of laser monitoring techniques of pollutants in atmosphere

    International Nuclear Information System (INIS)

    Hassan, T. A. A.

    2006-01-01

    There are several techniques used as a tool for monitoring the pollutions in the atmosphere, where the laser radiation sending through the sample of atmosphere to be investigated ether transmission or the scattering of the light, all the way through a variety of different techniques for monitoring the air quality. We are showed in this study the comparison of detection techniques through measuring the light scattered in some particular direction, rather than measuring direction the attenuation due to two type of scattering (Rayieh scattering and Mie scattering) during (optical Radar, Roman backscattering and Resonance fluorescence).(Author)

  10. Power distribution monitoring and control in the RBMK type reactors

    International Nuclear Information System (INIS)

    Emel'yanov, I.Ya.; Postnikov, V.V.; Volod'ko, Yu.I.

    1980-01-01

    Considered are the structures of monitoring and control systems for the RBMK-1000 reactor including three main systems with high independence: the control and safety system (CSS); the system for physical control of energy distribution (SPCED) as well as the Scala system for centralized control (SCC). Main functions and peculiarities of each system are discussed. Main attention is paid to new structural solutions and new equipment components used in these systems. Described are the RBMK operation software and routine of energy distribution control in it. It is noted that the set of reactor control and monitoring systems has a hierarchical structure, the first level of which includes analog systems (CSS and SPCED) normalizing and transmitting detector signals to the systems of the second level based on computers and realizing computer data processing, data representation to the operator, automatic (through CSS) control for energy distribution, diagnostics of equipment condition and local safety with provision for existing reserves with respect to crisis and thermal loading of fuel assemblies. The third level includes a power computer carrying out complex physical and optimization calculations and providing interconnections with the external computer of power system. A typical feature of the complex is the provision of local automatic safety of the reactor from erroneous withdrawal of any control rod. The complex is designed for complete automatization of energy distribution control in reactor in steady and transient operation conditions

  11. A new type of intelligent wireless sensing network for health monitoring of large-size structures

    Science.gov (United States)

    Lei, Ying; Liu, Ch.; Wu, D. T.; Tang, Y. L.; Wang, J. X.; Wu, L. J.; Jiang, X. D.

    2009-07-01

    In recent years, some innovative wireless sensing systems have been proposed. However, more exploration and research on wireless sensing systems are required before wireless systems can substitute for the traditional wire-based systems. In this paper, a new type of intelligent wireless sensing network is proposed for the heath monitoring of large-size structures. Hardware design of the new wireless sensing units is first studied. The wireless sensing unit mainly consists of functional modules of: sensing interface, signal conditioning, signal digitization, computational core, wireless communication and battery management. Then, software architecture of the unit is introduced. The sensing network has a two-level cluster-tree architecture with Zigbee communication protocol. Important issues such as power saving and fault tolerance are considered in the designs of the new wireless sensing units and sensing network. Each cluster head in the network is characterized by its computational capabilities that can be used to implement the computational methodologies of structural health monitoring; making the wireless sensing units and sensing network have "intelligent" characteristics. Primary tests on the measurement data collected by the wireless system are performed. The distributed computational capacity of the intelligent sensing network is also demonstrated. It is shown that the new type of intelligent wireless sensing network provides an efficient tool for structural health monitoring of large-size structures.

  12. Studies of beam position monitor stability

    International Nuclear Information System (INIS)

    Tenenbaum, P.

    1998-05-01

    The authors present the result s from two studies of the time stability between the mechanical center of a beam position monitor and its electrical/electronic center. In the first study, a group of 93 BPM processors was calibrated via Test Pulse Generator once per hour in order to measure the contribution of the readout electronics to offset drifts. In the second study, a triplet of stripline BPMs in the Final Focus Test Beam, separated only by drift spaces, was read out every 6 minutes during 1 week of beam operation. In both cases offset stability was observed to be on the order of microns over time spans ranging from hours to days, although during the beam study much worse performance was also observed. Implications for the beam position monitor system of future linear collider systems are discussed

  13. Monitoring of fire incidences in vegetation types and Protected ...

    Indian Academy of Sciences (India)

    two types of sensor data, i.e., AWiFS and MODIS, have found fires in 281 (out of 614) Protected Areas of India. .... 56 m resolution prepared as part of national car- bon project has ...... and its deficiency in India were pointed out as back- ground.

  14. Multilayer mirror based monitors for impurity controls in large fusion reactor type devices

    International Nuclear Information System (INIS)

    Regan, S.P.; May, M.J.; Soukhanovskii, V.; Finkenthal, M.; Moos, H.W.

    1995-01-01

    Multilayer Mirror (MLM) based monitors are compact, high throughput diagnostics capable of extracting XUV emissions (the wavelength range including the soft-x-ray and the extreme ultraviolet, 10 angstrom to 304 angstrom) of impurities from the harsh environment of large fusion reactor type devices. For several years the Plasma Spectroscopy Group at Johns Hopkins University has investigated the application of MLM based XUV spectroscopic diagnostics for magnetically confined fusion plasmas. MLM based monitors have been constructed for and extensively used on DIII-D, Alcator C-mod, TEXT, Phaedrus-T, and CDX-U tokamaks to study the impurity behavior of elements ranging from He to Mo. On ITER MLM based devices would be used to monitor the spectral line emissions from Li I-like to F I-like charge states of Fe, Cr, and Ni, as well as extractors for the bands of emissions from high Z elements such as Mo or W for impurity controls of the fusion plasma. In addition to monitoring the impurity emissions from the main plasma, MLM based devices can also be adapted for radiation measurements of low Z elements in the divertor. The concepts and designs of these MLM based monitors for impurity controls in ITER will be presented. The results of neutron irradiation experiments of the MLMs performed in the Los Alamos Spallation Radiation Effects Facility (LASREF) at the Los Alamos National Laboratory will also be discussed. These preliminary neutron exposure studies show that the dispersive and reflective qualities of the MLMs were not affected in a significant manner

  15. Research project implementation of a risk-based performance monitoring system for nuclear power plants: Phase II - Type-D indicators. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Sewell, R.T. [EQE International. Inc., Evergreen, CO (United States); Khatib-Rahbar, M. [Energy Research, Inc., Rockville, MD (United States); Erikson, H. [Swedish Nuclear Power Inspectorate, Stockholm (Sweden)

    1999-02-01

    This study has established the basis for incorporating a meaningful set of Type-D performance indicators into an overall performance monitoring system based on a PSA framework. The relationships developed as part of this study enable various organizational, maintenance, and operational influences, that are manifested through key events that can be identified and reported at a plant, to be accounted for in terms of their impacts on safety. The relationships and the capability they pose are significant new and unique developments. The relationships require that plant-specific data on the key performance indicators be acquired and analyzed. This, in turn, necessitates that a regular and systematic supplementary data collection program be implemented. Hence, it is recommended here that such a data program be developed and undertaken, specifically within the context of an overall PSA-based safety monitoring system. Plant licensees should be responsible for the supplemental data collection effort; however, the data collection requirements should not pose an undue burden on the licensees. To the extent possible, the data collection program should be coordinated, and possibly integrated, with existing licensee data collection and event reporting efforts. This study was undertaken to help verify whether or not it would be feasible to proceed with a PSA-based performance monitoring program. Research performed for Part-1 investigation has resulted in the development of a systematic and structured approach for monitoring safety performance based on all types of plant events. The Type-D relationships were earlier identified as a key element of the proposed performance monitoring system, and if it would be discovered that the Type-D relationships could not be practically developed and implemented, then it would have lead to the recognition that the performance monitoring system might have little practical value. On the other hand, if the Type-D relationships could be efficiently

  16. Research project implementation of a risk-based performance monitoring system for nuclear power plants: Phase II - Type-D indicators. Final report

    International Nuclear Information System (INIS)

    Sewell, R.T.; Khatib-Rahbar, M.; Erikson, H.

    1999-02-01

    This study has established the basis for incorporating a meaningful set of Type-D performance indicators into an overall performance monitoring system based on a PSA framework. The relationships developed as part of this study enable various organizational, maintenance, and operational influences, that are manifested through key events that can be identified and reported at a plant, to be accounted for in terms of their impacts on safety. The relationships and the capability they pose are significant new and unique developments. The relationships require that plant-specific data on the key performance indicators be acquired and analyzed. This, in turn, necessitates that a regular and systematic supplementary data collection program be implemented. Hence, it is recommended here that such a data program be developed and undertaken, specifically within the context of an overall PSA-based safety monitoring system. Plant licensees should be responsible for the supplemental data collection effort; however, the data collection requirements should not pose an undue burden on the licensees. To the extent possible, the data collection program should be coordinated, and possibly integrated, with existing licensee data collection and event reporting efforts. This study was undertaken to help verify whether or not it would be feasible to proceed with a PSA-based performance monitoring program. Research performed for Part-1 investigation has resulted in the development of a systematic and structured approach for monitoring safety performance based on all types of plant events. The Type-D relationships were earlier identified as a key element of the proposed performance monitoring system, and if it would be discovered that the Type-D relationships could not be practically developed and implemented, then it would have lead to the recognition that the performance monitoring system might have little practical value. On the other hand, if the Type-D relationships could be efficiently

  17. Development of mediator-type biosensor to wirelessly monitor whole cholesterol concentration in fish.

    Science.gov (United States)

    Takase, Mai; Murata, Masataka; Hibi, Kyoko; Huifeng, Ren; Endo, Hideaki

    2014-04-01

    We developed a wireless monitoring system to monitor fish condition by tracking the change in whole cholesterol concentration. The whole cholesterol concentration of fish is a source of steroid hormones or indicator of immunity level, which makes its detection important for tracking physiological condition of fish. Wireless monitoring system comprises of mediator-type biosensor and wireless transmission device. Biosensor is implantable to fish body, and transmission device is so light, in that fish is allowed to swim freely during monitoring. Cholesterol esterase and oxidase were fixated on to the detection site of biosensor and used to detect the whole cholesterol concentration. However, cholesterol oxidase incorporates oxidation-reduction reaction of oxygen for detection, which concentration fluctuates easily due to change in environmental condition. Meanwhile, mediator-type biosensor enables monitoring of whole cholesterol concentration by using mediator to substitute that oxidation-reduction reaction of oxygen. Characteristic of fabricated mediator-type biosensor was tested. The sensor output current of mediator-type biosensor remained stable compared to output current of non-mediator-type biosensor under fluctuating oxygen concentration of 0-8 ppm, which implied that this sensor is less affected by change in dissolved oxygen concentration. That biosensor was then implanted into fish for wireless monitoring. As a result, approximately 48 h of real-time monitoring was successful.

  18. Self-monitoring of blood glucose experiences of adults with type 2 diabetes.

    Science.gov (United States)

    Dlugasch, Lucie B; Ugarriza, Doris N

    2014-06-01

    The purpose of this study was to analyze the experiences of self-monitoring of blood glucose (SMBG) usage of adults with type 2 diabetes mellitus (T2DM) who are not using insulin. Nineteen adults were asked to describe their experiences with self-monitoring. Data were analyzed using the grounded theory method. The theory of "SMBG as a Cue in T2DM Self-Care" emerged from the data and is composed of four categories: (a) Engaging, (b) Checking, (c) Responding, and (d) Establishing a Pattern. Engaging marks the beginning. Frequent monitoring characterizes this stage. Checking involves evaluating and validating the blood glucose level. The most common item evaluated or validated was the effect of foods. Responding involves taking action or experiencing emotion. Actions taken centered on dietary changes. Emotions felt were dependent on the level and ranged from blame to happiness. Participants established a pattern and used SMBG regularly or sporadically. Frequency was based on obtaining "normal" patterns, the absence of symptoms, provider disinterest, and fingertip pain. Participants described many benefits and struggles when incorporating SMBG into their self-care. Information from this study could be used to develop effective guidelines for the use of SMBG in T2DM. ©2013 The Author(s) ©2013 American Association of Nurse Practitioners.

  19. Study on Laser Welding Process Monitoring Method

    OpenAIRE

    Knag , Heeshin

    2017-01-01

    International audience; In this paper, a study of quality monitoring technology for the laser welding was conducted. The laser welding and the industrial robotic systems were used with robot-based laser welding systems. The laser system used in this study was 1.6 kW fiber laser, while the robot system was Industrial robot (pay-load : 130 kg). The robot-based laser welding system was equipped with a laser scanner system for remote laser welding. The welding joints of steel plate and steel plat...

  20. Study on Laser Welding Process Monitoring Method

    OpenAIRE

    Heeshin Knag

    2016-01-01

    In this paper, a study of quality monitoring technology for the laser welding was conducted. The laser welding and the industrial robotic systems were used with robot-based laser welding systems. The laser system used in this study was 1.6 kW fiber laser, while the robot system was Industrial robot (pay-load : 130 kg). The robot-based laser welding system was equipped with a laser scanner system for remote laser welding. The welding joints of steel plate and steel plate coated with zinc were ...

  1. [Profile of patients with diabetes type 1: insulinotherapy and self-monitoring].

    Science.gov (United States)

    Almeida, Henriqueta Galvanin Guidio de; Campos, Joao Jose Batista; Kfouri, Christiane; Tanita, Marcos Toshiyuki; Dias, Adriana Espinosa; Souza, Marizia Marcos de

    2002-01-01

    A study carried out in Londrina - PR, with the cohort of local patients from Brazilian Study on the incidence of Diabetes Mellitus Type 1 (EDID). To know the insulin treatment and the plan for glycemic self-monitoring used by these patients; to verify their knowledge as for what they consider the optimization of these parameters and limitations of use. A survey was conducted with objective questions to 63 patients of the cohort. The average age was 13 years, without gender predominance. It was verified that most of the patients, 79.36%, (n=50) took at least 2 daily applications of insulin. All of them used insulin NPH in one (n=13) or two (n=50) doses. The use of regular insulin, in variable programs, was associated to the NPH in 41.27% (n=26) of the patients (The most frequent insulin type used was human 53.97% (n=34). Of the patients not making use of human insulin, 44.83% (n=13) considered it of high cost and 95.24% (n=60) would make use of it if it was distributed by the Government Unified Health System. As for the monitoring, 63.40% (n=40) took the tests up to 7 times a week, 20.63% (n=13) from 15 to 21 and only 1 patient from 29 to 35 tests. The high cost was the reason for 48.21% (n=27) not to take the tests; 58.73% (n=37) would take the test in the blood and 33.33% (n=21) either in the blood or in the urine if they were given the reactive ribbons. In this cohort of patients, although the human insulin is already adopted as the use of choice, the outline insulin treatment plan is still traditional and the monitoring is far behind the ideal.

  2. Monitoring what is real: The effects of modality and action on accuracy and type of reality monitoring error.

    Science.gov (United States)

    Garrison, Jane R; Bond, Rebecca; Gibbard, Emma; Johnson, Marcia K; Simons, Jon S

    2017-02-01

    Reality monitoring refers to processes involved in distinguishing internally generated information from information presented in the external world, an activity thought to be based, in part, on assessment of activated features such as the amount and type of cognitive operations and perceptual content. Impairment in reality monitoring has been implicated in symptoms of mental illness and associated more widely with the occurrence of anomalous perceptions as well as false memories and beliefs. In the present experiment, the cognitive mechanisms of reality monitoring were probed in healthy individuals using a task that investigated the effects of stimulus modality (auditory vs visual) and the type of action undertaken during encoding (thought vs speech) on subsequent source memory. There was reduced source accuracy for auditory stimuli compared with visual, and when encoding was accompanied by thought as opposed to speech, and a greater rate of externalization than internalization errors that was stable across factors. Interpreted within the source monitoring framework (Johnson, Hashtroudi, & Lindsay, 1993), the results are consistent with the greater prevalence of clinically observed auditory than visual reality discrimination failures. The significance of these findings is discussed in light of theories of hallucinations, delusions and confabulation. Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.

  3. Application of the Continuous-Discrete Extended Kalman Filter for Fault Detection in Continuous Glucose Monitors for Type 1 Diabetes

    DEFF Research Database (Denmark)

    Mahmoudi, Zeinab; Boiroux, Dimitri; Hagdrup, Morten

    2016-01-01

    The purpose of this study is the online detection of faults and anomalies of a continuous glucose monitor (CGM). We simulated a type 1 diabetes patient using the Medtronic virtual patient model. The model is a system of stochastic differential equations and includes insulin pharmacokinetics...

  4. New types of time domain reflectometry sensing waveguides for bridge scour monitoring

    Science.gov (United States)

    Lin, Chih-Ping; Wang, Kai; Chung, Chih-Chung; Weng, Yu-Wen

    2017-07-01

    Scour is a major threat to bridge safety, especially in harsh fluvial environments. Real-time monitoring of bridge scour is still very limited due to the lack of robust and economic scour monitoring device. Time domain reflectometry (TDR) is an emerging waveguide-based technique holding great promise to develop more durable scour monitoring devices. This study presents new types of TDR sensing waveguides in forms of either sensing rod or sensing wire, taking into account of the measurement range, durability, and ease of field installation. The sensing rod is composed of a hollow grooved steel rod paired up with a metal strip on the insulating groove, while the sensing wire consists of two steel strands with one of them coated with an insulating jacket. The measurement sensitivity is inevitably sacrificed when other properties such as the measurement range, field durability, and installation easiness are enhanced. Factors affecting the measurement sensitivity were identified and experimentally evaluated for better arranging the waveguide conductors. A data reduction method for scour-depth estimation without the need for identifying the sediment/water reflection and a two-step calibration procedure for rating propagation velocities were proposed to work with the new types of TDR sensing waveguides. Both the calibration procedure and the data reduction method were experimentally validated. The test results indicated that the new TDR sensing waveguide provides accurate scour depth measurements regardless of the sacrificed sensitivity. The insulating coating of the new TDR sensing waveguide was also demonstrated to be effective in extending the measurement range up to at least 15 m.

  5. Cyanobacteria, Toxins and Indicators: Field Monitoring,Treatment Facility Monitoring and Treatment Studies

    Science.gov (United States)

    This presentation is a compilation of harmful algal bloom (HAB) related field monitoring data from the 2015 bloom season, treatment plant monitoring data from the 2013 and 2014 bloom seasons, and bench-scale treatment study data from 2015.

  6. A study on the condition monitoring for safety-related electric cables

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chul Hwan; Ahn, S. P.; Yeo, S. M.; Kang, Y. S.; Ahn, S. M.; Kim, I. S.; Kim, D. S.; Kang, J. S. [Sungkyunkwan Univ., Suwon (Korea, Republic of)

    2002-03-15

    In this report, we have studied compositions and characteristics of various types of insulation material for cables in Nuclear Power Plant. We arrange relationship with condition monitoring methods. Also, we propose new condition monitoring method using third harmonic frequency. We test the proposed method with CV cables. We also describe about feature of condition monitoring such as application, theory, characteristic, thereby other engineer can confirm to advantage and disadvantage for each method, and possibly choice adequate condition monitoring method for various types of cables.

  7. Pedestrian injury causation study (pedestrian accident typing)

    Science.gov (United States)

    1982-08-01

    A new computerized pedestrian accident typing procedure was tested on 1,997 cases from the Pedestrian Injury Causation Study (PICS). Two coding procedures were used to determine the effects of quantity and quality of information on accident typing ac...

  8. Professional continuous glucose monitoring for the identification of type 1 diabetes mellitus among subjects with insulin therapy.

    Science.gov (United States)

    Chen, Yin-Chun; Huang, Yu-Yao; Li, Hung-Yuan; Liu, Shih-Wei; Hsieh, Sheng-Hwu; Lin, Chia-Hung

    2015-01-01

    The identification of type 1 diabetes in diabetic subjects receiving insulin therapy is sometimes difficult. The purpose of this study is to evaluate whether results of professional continuous glucose monitoring can improve the identification of type 1 diabetes.From 2007 to 2012, 119 adults receiving at least twice-daily insulin therapy and professional continuous glucose monitoring were recruited. Type 1 diabetes was diagnosed by endocrinologists according to American Diabetes Association standards, including a very low C-peptide level (diabetic ketoacidosis. Continuous glucose monitoring was applied for 3 days.Among 119 subjects, 86 were diagnosed with type 1 diabetes. Subjects with type 1 diabetes were younger (33.8 vs 52.3 years old, P 1), had lower body mass index (BMI, 21.95 vs 24.42, P = 0.003), lower serum creatinine (61.77  vs 84.65 μmol/L, P = 0.001), and higher estimated glomerular filtration rate (108.71 vs 76.48 mg/mL/min/1.73m2, P 1) than subjects with type 2 diabetes. Predictive scores for identification of type 1 diabetes were constructed, including age, BMI, average mean amplitude of glucose excursion in days 2 and 3, and the area under the curve of nocturnal hyperglycemic and hypoglycemic states. The area under the receiver operating characteristic curve was 0.90. With the cutoff of 0.58, the sensitivity was 86.7% and the specificity was 80.8%. The good performance was validated by the leave-one-out method (sensitivity 83.3%, specificity 73.1%).Professional continuous glucose monitoring is a useful tool that improves identification of type 1 diabetes among diabetic patients receiving insulin therapy.

  9. Perceptions of Caribbean type 2 diabetes patients on self-monitoring of blood glucose

    DEFF Research Database (Denmark)

    Ezenwaka, C. E.; Olukoga, A.; Onuoha, P.

    2012-01-01

    Context: The views of type 2 diabetes (T2DM) patients have not been considered in the debate on the role of self-monitoring of blood glucose (SMBG) in the management of T2DM. Objective: To assess the views of T2DM patients on SMBG. Methods: Two previously trained research assistants used a struct......Context: The views of type 2 diabetes (T2DM) patients have not been considered in the debate on the role of self-monitoring of blood glucose (SMBG) in the management of T2DM. Objective: To assess the views of T2DM patients on SMBG. Methods: Two previously trained research assistants used...

  10. Blood Glucose Monitoring Before and After Type 1 Diabetes Clinic Visits.

    Science.gov (United States)

    Driscoll, Kimberly A; Johnson, Suzanne Bennett; Wang, Yuxia; Wright, Nancy; Deeb, Larry C

    2017-12-23

    To determine patterns of blood glucose monitoring in children and adolescents with type 1 diabetes (T1D) before and after routine T1D clinic visits. Blood glucose monitoring data were downloaded at four consecutive routine clinic visits from children and adolescents aged 5-18 years. Linear mixed models were used to analyze patterns of blood glucose monitoring in patients who had at least 28 days of data stored in their blood glucose monitors. In general, the frequency of blood glucose monitoring decreased across visits, and younger children engaged in more frequent blood glucose monitoring. Blood glucose monitoring increased before the T1D clinic visits in younger children, but not in adolescents. It declined after the visit regardless of age. Members of the T1D care team need to consider that a T1D clinic visit may prompt an increase in blood glucose monitoring when making treatment changes and recommendations. Tailored interventions are needed to maintain that higher level of adherence across time. © The Author(s) 2017. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

  11. Study on sampling conditions for the monitoring of waste air

    International Nuclear Information System (INIS)

    Moeller, T.J.; Buetefisch, K.A.

    1998-01-01

    The technical codes for radiological monitoring of the waste air released from a radwaste repository demand that sampling for determination of aerosol-borne radioactivity is to be made with a screener equipped with a suitable number of measuring probes extending over the entire cross-sectional surface of the vent. Another requirement is to ensure that the waste air stream passing through the measuring channel is representative, containing the typical, operation-induced distribution of aerosols across the surface to be scanned. The study reported was intended to determine in a scaled-down model (1:10) of a repository ventilating duct the typical spatial distribution of aerosols (3D particulate density) in order to establish information on the type of typical distributions of aerosols, to be used for optimisation of the measuring site and monitoring instruments. (orig./CB) [de

  12. Dose linearity and monitor unit stability of a G4 type cyberknife robotic stereotactic radiosurgery system

    International Nuclear Information System (INIS)

    Sudahar, H.; Kurup, P.G.G.; Murali, V.; Velmurugan, J.

    2012-01-01

    Dose linearity studies on conventional linear accelerators show a linearity error at low monitor units (MUs). The purpose of this study was to establish the dose linearity and MU stability characteristics of a cyberknife (Accuracy Inc., USA) stereotactic radiosurgery system. Measurements were done at a depth of 5 cm in a stereotactic dose verification phantom with a source to surface distance of 75 cm in a Generation 4 (G4) type cyberknife system. All the 12 fixed-type collimators starting from 5 to 60 mm were used for the dose linearity study. The dose linearity was examined in small (1-10), medium (15-100) and large (125-1000) MU ranges. The MU stability test was performed with 60 mm collimator for 10 MU and 20 MU with different combinations. The maximum dose linearity error of -38.8% was observed for 1 MU with 5 mm collimator. Dose linearity error in the small MU range was considerably higher than in the medium and large MU ranges. The maximum error in the medium range was -2.4%. In the large MU range, the linearity error varied between -0.7% and 1.2%. The maximum deviation in the MU stability was -3.03%. (author)

  13. Study of type III ELMs in JET

    NARCIS (Netherlands)

    Sartori, R.; Saibene, G.; Horton, L. D.; Becoulet, M.; Budny, R.; Borba, D.; Chankin, A.; Conway, G. D.; Cordey, G.; McDonald, D.; Guenther, K.; von Hellermann, M. G.; Igithkanov, Y.; Loarte, A.; Lomas, P. J.; Pogutse, O.; Rapp, J.

    2004-01-01

    This paper presents the results of JET experiments aimed at studying the operational space of plasmas with a Type III ELMy edge, in terms of both local and global plasma parameters. In JET, the Type III ELMy regime has a wide operational space in the pedestal n(e)-T-e diagram, and Type III ELMs are

  14. Virologic Monitoring of Poliovirus Type 2 after Oral Poliovirus Vaccine Type 2 Withdrawal in April 2016 - Worldwide, 2016-2017.

    Science.gov (United States)

    Diop, Ousmane M; Asghar, Humayun; Gavrilin, Evgeniy; Moeletsi, Nicksy Gumede; Benito, Gloria Rey; Paladin, Fem; Pattamadilok, Sirima; Zhang, Yan; Goel, Ajay; Quddus, Arshad

    2017-05-26

    The Global Polio Eradication Initiative (GPEI) has made substantial progress since its launch in 1988; only 37 wild poliovirus type 1 (WPV1) cases were detected in 2016, the lowest annual count ever. Wild poliovirus type 3 has not been detected since November 2012, and wild poliovirus type 2 was officially declared eradicated in September 2015. This success is attributable to the wide use of live oral poliovirus vaccines (OPVs). Since 2001, numerous outbreaks were caused by the emergence of genetically divergent vaccine-derived polioviruses (VDPVs) whose genetic drift from the parental OPV strains indicates prolonged replication or circulation (1). In 2015, circulating VDPV type 2 (cVDPV2) outbreaks were detected in five countries worldwide (Nigeria, Pakistan, Guinea, Burma, and South Sudan), and VDPV2 single events were reported in 22 countries. These events prompted the GPEI to withdraw the type 2 component (Sabin2) of trivalent OPV (tOPV) in a globally coordinated, synchronized manner in April 2016 (2,3), at which time all OPV-using countries switched to using bivalent OPV (bOPV), containing Sabin types 1 and 3. This report details for the first time the virologic tracking of elimination of a live vaccine that has been withdrawn from routine and mass immunization systems worldwide (3). To secure elimination, further monitoring is warranted to detect any use of tOPV or monovalent OPV type 2 (mOPV2).

  15. Accuracy of Consumer Monitors for Estimating Energy Expenditure and Activity Type.

    Science.gov (United States)

    Woodman, James A; Crouter, Scott E; Bassett, David R; Fitzhugh, Eugene C; Boyer, William R

    2017-02-01

    Increasing use of consumer-based physical activity (PA) monitors necessitates that they are validated against criterion measures. Thus, the purpose of this study was to examine the accuracy of three consumer-based PA monitors for estimating energy expenditure (EE) and PA type during simulated free-living activities. Twenty-eight participants (mean ± SD: age, 25.5 ± 3.7 yr; body mass index, 24.9 ± 2.6 kg·m) completed 11 activities ranging from sedentary behaviors to vigorous intensities. Simultaneous measurements were made with an Oxycon portable calorimeter (criterion), a Basis Peak and Garmin Vivofit on the nondominant wrist, and three Withings Pulse devices (right hip, shirt collar, dominant wrist). Repeated-measures ANOVA were used to examine differences between measured and predicted EE. Intraclass correlation coefficients were calculated to determine reliability of EE predictions between Withings placements. Paired samples t tests were used to determine mean differences between observed minutes and Basis Peak predictions during walking, running, and cycling. On average, the Basis Peak was within 8% of measured EE for the entire PA routine (P > 0.05); however, there were large individual errors (95% prediction interval, -290.4 to +233.1 kcal). All other devices were significantly different from measured EE for the entire PA routine (P types, Basis Peak correctly identified ≥92% of actual minutes spent walking and running (P > 0.05), and 40.4% and 0% of overground and stationary cycling minutes, respectively (P < 0.001). The Basis Peak was the only device that did not significantly differ from measured EE; however, it also had the largest individual errors. Additionally, the Basis Peak accurately predicted minutes spent walking and running, but not cycling.

  16. The value of episodic, intensive blood glucose monitoring in non-insulin treated persons with Type 2 Diabetes: design of the Structured Testing Program (STeP) study, a cluster-randomised, clinical trial [NCT00674986].

    Science.gov (United States)

    Polonsky, William; Fisher, Lawrence; Schikman, Charles; Hinnen, Deborah; Parkin, Christopher; Jelsovsky, Zhihong; Amstutz, Linda; Schweitzer, Matthias; Wagner, Robin

    2010-05-18

    The value and utility of self-monitoring of blood glucose (SMBG) in non-insulin treated T2DM has yet to be clearly determined. Findings from studies in this population have been inconsistent, due mainly to design differences and limitations, including the prescribed frequency and timing of SMBG, role of the patient and physician in responding to SMBG results, inclusion criteria that may contribute to untoward floor effects, subject compliance, and cross-arm contamination. We have designed an SMBG intervention study that attempts to address these issues. The Structured Testing Program (STeP) study is a 12-month, cluster-randomised, multi-centre clinical trial to evaluate whether poorly controlled (HbA1c >or= 7.5%), non-insulin treated T2DM patients will benefit from a comprehensive, integrated physician/patient intervention using structured SMBG in US primary care practices. Thirty-four practices will be recruited and randomly assigned to an active control group (ACG) that receives enhanced usual care or to an enhanced usual care group plus structured SMBG (STG). A total of 504 patients will be enrolled; eligible patients at each site will be randomly selected using a defined protocol. Anticipated attrition of 20% will yield a sample size of at least 204 per arm, which will provide a 90% power to detect a difference of at least 0.5% in change from baseline in HbA1c values, assuming a common standard deviation of 1.5%. Differences in timing and degree of treatment intensification, cost effectiveness, and changes in patient self-management behaviours, mood, and quality of life (QOL) over time will also be assessed. Analysis of change in HbA1c and other dependent variables over time will be performed using both intent-to-treat and per protocol analyses. Trial results will be available in 2010. The intervention and trial design builds upon previous research by emphasizing appropriate and collaborative use of SMBG by both patients and physicians. Utilization of per

  17. The value of episodic, intensive blood glucose monitoring in non-insulin treated persons with type 2 diabetes: Design of the Structured Testing Program (STeP Study, a cluster-randomised, clinical trial [NCT00674986

    Directory of Open Access Journals (Sweden)

    Jelsovsky Zhihong

    2010-05-01

    Full Text Available Abstract Background The value and utility of self-monitoring of blood glucose (SMBG in non-insulin treated T2DM has yet to be clearly determined. Findings from studies in this population have been inconsistent, due mainly to design differences and limitations, including the prescribed frequency and timing of SMBG, role of the patient and physician in responding to SMBG results, inclusion criteria that may contribute to untoward floor effects, subject compliance, and cross-arm contamination. We have designed an SMBG intervention study that attempts to address these issues. Methods/design The Structured Testing Program (STeP study is a 12-month, cluster-randomised, multi-centre clinical trial to evaluate whether poorly controlled (HbA1c ≥ 7.5%, non-insulin treated T2DM patients will benefit from a comprehensive, integrated physician/patient intervention using structured SMBG in US primary care practices. Thirty-four practices will be recruited and randomly assigned to an active control group (ACG that receives enhanced usual care or to an enhanced usual care group plus structured SMBG (STG. A total of 504 patients will be enrolled; eligible patients at each site will be randomly selected using a defined protocol. Anticipated attrition of 20% will yield a sample size of at least 204 per arm, which will provide a 90% power to detect a difference of at least 0.5% in change from baseline in HbA1c values, assuming a common standard deviation of 1.5%. Differences in timing and degree of treatment intensification, cost effectiveness, and changes in patient self-management behaviours, mood, and quality of life (QOL over time will also be assessed. Analysis of change in HbA1c and other dependent variables over time will be performed using both intent-to-treat and per protocol analyses. Trial results will be available in 2010. Discussion The intervention and trial design builds upon previous research by emphasizing appropriate and collaborative use of

  18. Disentangling the roles of parental monitoring and family conflict in adolescents' management of type 1 diabetes.

    Science.gov (United States)

    Hilliard, Marisa E; Holmes, Clarissa S; Chen, Rusan; Maher, Kathryn; Robinson, Elizabeth; Streisand, Randi

    2013-04-01

    Less parental monitoring of adolescents' diabetes self-care and more family conflict are each associated with poorer diabetes outcomes. However, little is known about how these two family factors relate with one another in the context of self-care and glycemic control. Diabetes self-care was evaluated as a mediator of the associations among parental monitoring, family conflict, and glycemic control in early adolescents with type 1 diabetes. Adolescent-parent dyads (n = 257) reported on the frequency of parental monitoring, family conflict, and diabetes self-care. Hemoglobin A1c was abstracted from medical charts. Structural equation modeling was used for mediation analysis. A mediation model linking parental involvement and family conflict with A1c through diabetes self-care fit the data well. Monitoring and conflict were inversely correlated (β = -0.23, p Conflict also was positively associated with higher A1c (β = 0.31, p conflict and less parental monitoring are risk factors for poorer glycemic control, and diabetes self-care is one mediator linking these variables. Interventions to promote parental monitoring of diabetes management during early adolescence may benefit from emphasizing strategies to prevent or reduce family conflict. 2013 APA, all rights reserved

  19. Development of a stripline-type position monitor for the KEK electron/positron linac

    International Nuclear Information System (INIS)

    Suwada, T.; Urano, T.; Lazos, A.; Kobayashi, H.

    1994-01-01

    A stripline-type beam-position monitor (BPM) is under development at the KEK electron/positron linac. This monitor will be installed in order to easily handle the orbit of a high-current electron beam (∼10 nC/pulse) generating a positron beam in the B-factory. The prototype BPM was tested at a test bench and then in the linac using a single-bunch electron beam. In this report some basic characteristics and the experimental results of the BPM are presented

  20. Development of a Method to Monitor Gene Expression in Single Bacterial Cells During the Interaction With Plants and Use to Study the Expression of the Type III Secretion System in Single Cells of Dickeya dadantii in Potato

    Directory of Open Access Journals (Sweden)

    Zhouqi Cui

    2018-06-01

    Full Text Available Dickeya dadantii is a bacterial plant pathogen that causes soft rot disease on a wide range of host plants. The type III secretion system (T3SS is an important virulence factor in D. dadantii. Expression of the T3SS is induced in the plant apoplast or in hrp-inducing minimal medium (hrp-MM, and is repressed in nutrient-rich media. Despite the understanding of induction conditions, how individual cells in a clonal bacterial population respond to these conditions and modulate T3SS expression is not well understood. In our previous study, we reported that in a clonal population, only a small proportion of bacteria highly expressed T3SS genes while the majority of the population did not express T3SS genes under hrp-MM condition. In this study, we developed a method that enabled in situ observation and quantification of gene expression in single bacterial cells in planta. Using this technique, we observed that the expression of the T3SS genes hrpA and hrpN is restricted to a small proportion of D. dadantii cells during the infection of potato. We also report that the expression of T3SS genes is higher at early stages of infection compared to later stages. This expression modulation is achieved through adjusting the ratio of T3SS ON and T3SS OFF cells and the expression intensity of T3SS ON cells. Our findings not only shed light into how bacteria use a bi-stable gene expression manner to modulate an important virulence factor, but also provide a useful tool to study gene expression in individual bacterial cells in planta.

  1. The Relationship Between a Balanced Time Perspective and Self-monitoring of Blood Glucose Among People With Type 1 Diabetes.

    Science.gov (United States)

    Baird, Harriet M; Webb, Thomas L; Martin, Jilly; Sirois, Fuschia M

    2018-05-10

    Self-monitoring of blood glucose helps people with type 1 diabetes to maintain glycemic control and reduce the risk of complications. However, adherence to blood glucose monitoring is often suboptimal. Like many health behaviors, self-monitoring of blood glucose involves exerting effort in the present to achieve future benefits. As such, the present research explored whether individual differences in time perspective-specifically, the extent to which people have a balanced time perspective-are associated with the frequency with which people with type 1 diabetes monitor their blood glucose and, thus, maintain glycemic control. Adults with type 1 diabetes completed measures of time perspective, feelings associated with monitoring, attitudes toward monitoring, and trait self-control. Objective data regarding the frequency with which participants monitored their blood glucose levels and their long-term glycemic control were extracted from their medical records. Hierarchical regression analyses and tests of indirect effects (N = 129) indicated that having a more balanced time perspective was associated with more frequent monitoring of blood glucose and, as a result, better glycemic control. Further analyses (N = 158) also indicated that there was an indirect relationship between balanced time perspective and monitoring of blood glucose via the feelings that participants associated with monitoring and their subsequent attitudes toward monitoring. These findings point to the importance and relevance of time perspective for understanding health-related behavior and may help to inform interventions designed to promote self-monitoring of blood glucose in people with type 1 diabetes.

  2. Study of Type III ELMs in JET

    Energy Technology Data Exchange (ETDEWEB)

    Sartori, R [EFDA Close Support Unit, Garching, 2 Boltzmannstrasse, Garching (Germany); Saibene, G [EFDA Close Support Unit, Garching, 2 Boltzmannstrasse, Garching (Germany); Horton, L D [Association Euratom-IPP, MPI fuer Plasmaphysik, 2 Boltzmannstrasse, Garching (Germany); Becoulet, M [Association Euratom-CEA, CE Cadarache, F-13108 St Paul-lez-Durance, CEDEX (France); Budny, R [PPPL, Princeton University, PO Box 451, Princeton, NJ 08543 (United States); Borba, D [Associacao EURATOM/IST, Centro de Fusao Nuclear, 1096 Lisbon, CODEX (Portugal); Chankin, A [Association Euratom-IPP, MPI fuer Plasmaphysik, 2 Boltzmannstrasse, Garching (Germany); Conway, G D [Association Euratom-IPP, MPI fuer Plasmaphysik, 2 Boltzmannstrasse, Garching (Germany); Cordey, G [EURATOM-UKAEA Fusion Association, Culham Science Centre, Abingdon, OX14 3DB (United Kingdom); McDonald, D [EURATOM-UKAEA Fusion Association, Culham Science Centre, Abingdon, OX14 3DB (United Kingdom); Guenther, K [EURATOM-UKAEA Fusion Association, Culham Science Centre, Abingdon, OX14 3DB (United Kingdom); Hellermann, M G von [FOM-Rijnhuizen, Ass. Euratom-FOM, TEC, PO Box 1207, 3430 BE Nieuwegein (Netherlands); Igithkanov, Yu [Max-Planck-Institute for Plasma Physics, Teilinstitut Greifswald, EURATOM Ass., D-17491, Greifswald (Germany); Loarte, A [EFDA Close Support Unit, Garching, 2 Boltzmannstrasse, Garching (Germany); Lomas, P J [EURATOM-UKAEA Fusion Association, Culham Science Centre, Abingdon, OX14 3DB (United Kingdom); Pogutse, O [EURATOM-UKAEA Fusion Association, Culham Science Centre, Abingdon, OX14 3DB (United Kingdom); Rapp, J [EFDA Close Support Unit, Culham, Abingdon OX14 3DB (United Kingdom)

    2004-05-01

    This paper presents the results of JET experiments aimed at studying the operational space of plasmas with a Type III ELMy edge, in terms of both local and global plasma parameters. In JET, the Type III ELMy regime has a wide operational space in the pedestal n{sub e} - T{sub e} diagram, and Type III ELMs are observed in standard ELMy H-modes as well as in plasmas with an internal transport barrier (ITB). The transition from an H-mode with Type III ELMs to a steady state Type I ELMy H-mode requires a minimum loss power, P{sub TypeI}. P{sub TypeI} decreases with increasing plasma triangularity. In the pedestal n{sub e} - T{sub e} diagram, the critical pedestal temperature for the transition to Type I ELMs is found to be inversely proportional to the pedestal density (T{sub crit} {proportional_to} 1/n) at a low density. In contrast, at a high density, T{sub crit}, does not depend strongly on density. In the density range where T{sub crit} {proportional_to} 1/n, the critical power required for the transition to Type I ELMs decreases with increasing density. Experimental results are presented suggesting a common mechanism for Type III ELMs at low and high collisionality. A single model for the critical temperature for the transition from Type III to Type I ELMs, based on the resistive interchange instability with magnetic flutter, fits well the density and toroidal field dependence of the JET experimental data. On the other hand, this model fails to describe the variation of the Type III n{sub e} - T{sub e} operational space with isotopic mass and q{sub 95}. Other results are instead suggestive of a different physics for Type III ELMs. At low collisionality, plasma current ramp experiments indicate a role of the edge current in determining the transition from Type III to Type I ELMs, while at high collisionality, a model based on resistive ballooning instability well reproduces, in term of a critical density, the experimentally observed q{sub 95} dependence of the

  3. Modernization of tritium in air monitoring system for CANDU type NPP

    International Nuclear Information System (INIS)

    Purghel, L.; Iancu, R.; Popescu, M.

    2009-01-01

    Nuclear energy provides at present one third of Europe's electricity with nearly no greenhouse-gas emissions. Sustained efforts are now being conducted to harmonize regulations all over Europe through WENRA and to converge on technical nuclear safety practices within the TSO network ETSON (European Technical Safety Organizations Network). In order to achieve this goals of safety function, IFIN-HH together with CITON developed a new solution to improve the Tritium Monitoring System (TMS) of Cernavoda NPP and the new generation of CANDU type reactors, using Tritium in air Intelligent Monitors (TIM) developed and patented by IFIN-HH. The paper presents a comparative analysis between the technical characteristics of traditional solutions implemented in CANDU type NPP, particularly in Cernavoda NPP Unit 2 and the newly proposed solution. (authors)

  4. Automatic vibration monitoring system for the diagnostic inspection of the WWER-440 type nuclear power plants

    International Nuclear Information System (INIS)

    Hollo, E.; Siklossy, P.; Toth, Zs.

    1982-01-01

    In the Hungarian Research Institute for Electric Power Industry (VEIKI) an automatic vibration monitoring system for diagnostics and inspection of nuclear power plants of type WWER-440 was developed. The paper summarizes the results of this work and investigates the use of mechanical vibrations and oscillations induced by flow for fault diagnosis. The design of the hardware system, the present software possibilities, the laboratory experiments and the guidelines for future software developments are also described in detail. (A.L.)

  5. Collimator type monochromator as a possible impurities monitor for fusion plasmas. Preliminary tests on the Tokamak TM-1-MH

    International Nuclear Information System (INIS)

    Musa, G.; Lungu, C.P.; Badalec, J.; Jakubka, K.; Kopecky, V.; Stoeckel, J.; Zacek, F.

    1984-09-01

    A collimator type monochromator has been tested for the first time as the impurity monitor on Tokamak. The possibility to use this type of monochromator in fusion devices is analyzed and a monoslit device is proposed as a convenient monitor for impurities. (authors)

  6. Evaluation of subcutaneous glucose monitoring systems under routine environmental conditions in patients with type 1 diabetes.

    Science.gov (United States)

    Aberer, Felix; Hajnsek, Martin; Rumpler, Markus; Zenz, Sabine; Baumann, Petra M; Elsayed, Hesham; Puffing, Adelheid; Treiber, Gerlies; Pieber, Thomas R; Sourij, Harald; Mader, Julia K

    2017-07-01

    Continuous and flash glucose monitoring (GM) systems have been established in diabetes care. We compared the sensor performance of 3 commercially available GM systems. A total of 12 patients with type 1 diabetes were included in a single-centre, open-label study in which the sensor performance of the Abbott FreeStyle libre (Abbott), Dexcom G4 Platinum (Dexcom) and Medtronic MiniMed 640G (Medtronic) systems over 12 hours was compared during mimicked real-life conditions (meals, exercise, hypo- and hyperglycaemia). Sensor performance was determined by fulfilment of ISO 15197:2013 criteria, calculating mean absolute relative difference (MARD), and was also illustrated using Parkes error grid and Bland-Altman plots. Sensor performance during changes in metabolic variables (lactate, betahydroxybutyrate, glucagon, non-esterified-fatty-acids) was determined by Spearman's rank correlation coefficient testing. The systems fulfilled ISO 15197:2013 criteria by 73.2% (Abbott), 56.1% (Dexcom) and 52.0% (Medtronic). The MARDs ± standard deviation in the entire glycaemic range were 13.2% ± 10.9% (Abbott), 16.8% ± 12.3% (Dexcom) and 21.4% ± 17.6% (Medtronic), respectively. All sensors performed less accurately during hypoglycaemia and best during hyperglycaemia. We did not observe an influence of metabolic variables on sensor performance. © 2017 John Wiley & Sons Ltd.

  7. Contract Monitoring in Agent-Based Systems: Case Study

    Science.gov (United States)

    Hodík, Jiří; Vokřínek, Jiří; Jakob, Michal

    Monitoring of fulfilment of obligations defined by electronic contracts in distributed domains is presented in this paper. A two-level model of contract-based systems and the types of observations needed for contract monitoring are introduced. The observations (inter-agent communication and agents’ actions) are collected and processed by the contract observation and analysis pipeline. The presented approach has been utilized in a multi-agent system for electronic contracting in a modular certification testing domain.

  8. Case Study - Monitoring the Photovoltaic Panels

    OpenAIRE

    PACURAR Ana Talida; TOADER Dumitru; PACURAR Cristian

    2014-01-01

    The photovoltaic cell represents one of the most dynamic and attractive way to converts renewable energy sources in electricity production. That means to convert solar energy into electricity. In this paper is presented a analogy between two types of photovoltaic panels installed, with educational role for students. Also the objective of this paper is to estimate the performance of photovoltaic panels and to provide the best solution for industry. These two types of photovoltaic panels wer...

  9. Optimizing study design for multi-species avian monitoring programmes

    Science.gov (United States)

    Jamie S. Sanderlin; William M. Block; Joseph L. Ganey

    2014-01-01

    Many monitoring programmes are successful at monitoring common species, whereas rare species, which are often of highest conservation concern, may be detected infrequently. Study designs that increase the probability of detecting rare species at least once over the study period, while collecting adequate data on common species, strengthen programme ability to address...

  10. Study on city underground NBC monitoring technology

    International Nuclear Information System (INIS)

    Hu Jiewei; Fang Zongliang; Wen Qilin; Cao Jianfeng; Peng Jing; Xu Feiyan

    2012-01-01

    Recent years, the NBC terrorism threat has become the major terrorist form which affects the national security and the public lives and properties. As the great power of politics and economy, and the main power of anti-terrorism around the world, China also faces the critical challenge of guarding against the NBC terrorist attack. The subway has become the main transportation due to its inexpensiveness and convenience, which also makes subway the target of terrorism attack. The paper discusses how to set up an NBC integrated monitoring technique suitable for city subways, and proposes a relative solution. (authors)

  11. Monitor of spatial plans. Feasibility study

    International Nuclear Information System (INIS)

    Bollen, M.J.S.; Ritsema van Eck, J.; Farjon, J.M.J.

    2008-01-01

    The national government needs assessments of consequences of building projects in relation to spatial policy objectives such as the prevention of urban sprawl or the development of landscape qualities. Normally the effects of spatial policies appear after several years. Spatial plans can possibly indicate these effects earlier. To allow policies to be adapted to unwanted developments, the assessments should be available in the early planning stages of these building projects. The Dutch Minister of VROM has asked the Netherlands Environmental Assessment Agency to investigate the feasibility of a monitoring system based on building plans. As building projects take a long period from conception until realization, a monitoring system for these projects should include all plans for the next ten to fifteen years with an indication of the chance that these plans are realized. The existing databases in the Netherlands provide sufficient information to assess consequences of plans for those objectives that are directly related to the urbanization pattern. However, an improvement of these databases is necessary, amongst other things by coordination of these databases [nl

  12. Aerosol typing - key information from aerosol studies

    Science.gov (United States)

    Mona, Lucia; Kahn, Ralph; Papagiannopoulos, Nikolaos; Holzer-Popp, Thomas; Pappalardo, Gelsomina

    2016-04-01

    Aerosol typing is a key source of aerosol information from ground-based and satellite-borne instruments. Depending on the specific measurement technique, aerosol typing can be used as input for retrievals or represents an output for other applications. Typically aerosol retrievals require some a priori or external aerosol type information. The accuracy of the derived aerosol products strongly depends on the reliability of these assumptions. Different sensors can make use of different aerosol type inputs. A critical review and harmonization of these procedures could significantly reduce related uncertainties. On the other hand, satellite measurements in recent years are providing valuable information about the global distribution of aerosol types, showing for example the main source regions and typical transport paths. Climatological studies of aerosol load at global and regional scales often rely on inferred aerosol type. There is still a high degree of inhomogeneity among satellite aerosol typing schemes, which makes the use different sensor datasets in a consistent way difficult. Knowledge of the 4d aerosol type distribution at these scales is essential for understanding the impact of different aerosol sources on climate, precipitation and air quality. All this information is needed for planning upcoming aerosol emissions policies. The exchange of expertise and the communication among satellite and ground-based measurement communities is fundamental for improving long-term dataset consistency, and for reducing aerosol type distribution uncertainties. Aerosol typing has been recognized as one of its high-priority activities of the AEROSAT (International Satellite Aerosol Science Network, http://aero-sat.org/) initiative. In the AEROSAT framework, a first critical review of aerosol typing procedures has been carried out. The review underlines the high heterogeneity in many aspects: approach, nomenclature, assumed number of components and parameters used for the

  13. Development of automated patrol-type monitoring and inspection system for nuclear power plant and application to actual plant

    International Nuclear Information System (INIS)

    Senoo, Makoto; Koga, Kazunori; Hirakawa, Hiroshi; Tanaka, Keiji

    1996-01-01

    An automated patrol-type monitoring and inspection system was developed and applied in a nuclear power plant. This system consists of a monorail, a monitoring robot and an operator's console. The monitoring robot consists of a sensor unit and a control unit. Three kinds of sensor, a color ITV camera, an infrared camera and a microphone are installed in the sensor unit. The features of this monitoring robot are; (1) Weights 15 kg with a cross-sectional dimensions of 152 mm width and 290 mm height. (2) Several automatic monitoring functions are installed using image processing and frequency analysis for three sensor signals. (author)

  14. Fast monitoring of indoor bioaerosol concentrations with ATP bioluminescence assay using an electrostatic rod-type sampler.

    Directory of Open Access Journals (Sweden)

    Ji-Woon Park

    Full Text Available A culture-based colony counting method is the most widely used analytical technique for monitoring bioaerosols in both indoor and outdoor environments. However, this method requires several days for colony formation. In this study, our goal was fast monitoring (Sampling: 3 min, Detection: < 1 min of indoor bioaerosol concentrations with ATP bioluminescence assay using a bioaerosol sampler. For this purpose, a novel hand-held electrostatic rod-type sampler (110 mm wide, 115 mm long, and 200 mm tall was developed and used with a commercial luminometer, which employs the Adenosine triphosphate (ATP bioluminescence method. The sampler consisted of a wire-rod type charger and a cylindrical collector, and was operated with an applied voltage of 4.5 kV and a sampling flow rate of 150.7 lpm. Its performance was tested using Staphylococcus epidermidis which was aerosolized with an atomizer. Bioaerosol concentrations were measured using ATP bioluminescence method with our sampler and compared with the culture-based method using Andersen cascade impactor under controlled laboratory conditions. Indoor bioaerosol concentrations were also measured using both methods in various indoor environments. A linear correlation was obtained between both methods in lab-tests and field-tests. Our proposed sampler with ATP bioluminescence method may be effective for fast monitoring of indoor bioaerosol concentrations.

  15. Study of an integrated electronic monitor for neutron beams

    International Nuclear Information System (INIS)

    Barelaud, B.; Nexon-Mokhtari, F.; Barrau, C.; Decossac, J.L.; Vareille, J.C.; Sarrabayrouse, G.

    1994-01-01

    Many neutron beams monitors in 10 keV - 50 keV range are perturbed by gamma radiation impact. This new monitor uses two silicon (junction) diodes operating coincidence detection, combined with an electronic threshold to eliminate gamma background noise. The results and analyses presented here only concern feasibility studies. (D.L.)

  16. Study of an integrated electronic monitor for neutron beams

    Energy Technology Data Exchange (ETDEWEB)

    Barelaud, B.; Nexon-Mokhtari, F.; Barrau, C.; Decossac, J.L.; Vareille, J.C. [Limoges Univ., 87 (France); Sarrabayrouse, G. [Centre National de la Recherche Scientifique (CNRS), 31 - Toulouse (France). Lab. d`Automatique et d`Analyse des Systemes

    1994-12-31

    Many neutron beams monitors in 10 keV - 50 keV range are perturbed by gamma radiation impact. This new monitor uses two silicon (junction) diodes operating coincidence detection, combined with an electronic threshold to eliminate gamma background noise. The results and analyses presented here only concern feasibility studies. (D.L.). 11 refs.

  17. Model Identification using Continuous Glucose Monitoring Data for Type 1 Diabetes

    DEFF Research Database (Denmark)

    Boiroux, Dimitri; Hagdrup, Morten; Mahmoudi, Zeinab

    2016-01-01

    This paper addresses model identification of continuous-discrete nonlinear models for people with type 1 diabetes using sampled data from a continuous glucose monitor (CGM). We compare five identification techniques: least squares, weighted least squares, Huber regression, maximum likelihood...... with extended Kalman filter and maximum likelihood with unscented Kalman filter. We perform the identification on a 24-hour simulation of a stochastic differential equation (SDE) version of the Medtronic Virtual Patient (MVP) model including process and output noise. We compare the fits with the actual CGM......, such as parameter tracking, population modeling and handling of outliers....

  18. Frequency and motives of blood glucose self-monitoring in type 1 diabetes

    DEFF Research Database (Denmark)

    Hansen, M V; Pedersen-Bjergaard, U; Heller, S R

    2009-01-01

    and demographic characteristics. METHODS: Cross-sectional Danish-British multicentre survey of 1076 consecutive patients with type 1 diabetes, who completed a detailed questionnaire on SMBG and related issues. The key variables were test frequency and motive. RESULTS: SMBG was performed daily by 39......AIMS: Recommendations for self-monitoring of blood glucose (SMBG) from the DCCT have not been implemented with the same rigour as recommendations for intensifying insulin therapy. We assessed the frequency of and motives for SMBG and compared SMBG behaviour with clinical, behavioural...

  19. Dissolved inorganic carbon, total alkalinity, dissolved oxygen, and pH monitored from benthic Free Ocean Carbon Enrichment (FOCE) -type study in Heron Island reef flat (NODC Accession 0113856)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Ocean acidification poses multiple challenges for coral reefs on molecular to ecological scales, yet previous experimental studies of the impact of projected CO2...

  20. Type studies in Coprinus subsection Lanatuli

    NARCIS (Netherlands)

    Uljé, C.B.; Noordeloos, M.E.

    2001-01-01

    As a prelude to a monograph of the genus Coprinus, types were studied of a number of species said to belong to Coprinus subsection Lanatuli (Coprinus alnivorus. C. alutaceivelatus, C. ammophilae, C. arachnoideus, C. asterophoroides, C. brunneistragulatus, C. bubalinus, C. citrinovelatus, C.

  1. Self-monitoring of blood glucose in patients with type 2 diabetes who are not using insulin.

    NARCIS (Netherlands)

    Welschen, L. M.; Bloemendal, E.; Nijpels, G.; Dekker, J. M.; Heine, R. J.; Stalman, W. A.; Bouter, L. M.

    2005-01-01

    BACKGROUND: Self-monitoring of blood glucose (SMBG) has been found to be effective for patients with type 1 diabetes and for patients with type 2 diabetes using insulin. There is much debate on the effectiveness of SMBG as a tool in the self-management for patients with type 2 diabetes who are not

  2. A study on impact monitoring using a piezoelectric paint sensor

    International Nuclear Information System (INIS)

    Choi, Kyung Woo; Kang, Dong Hoon; Park, Seung Bok; Kang, Lae Hyong

    2015-01-01

    The piezoelectric paint sensor is a paint type sensor comprising of an epoxy and piezoelectric powder, which is the main component of a piezoelectric material. This sensor can be easily attached to any type of structure as compared to other sensors because it is viable to directly apply it on structures, as in the case with a typical paint. In this study, the capability of piezoelectric paint sensor for impact detection was evaluated. In Particular, the applications of the piezoelectric paint sensor for railroad vehicles were considered. There have been various cases reported about the damages caused by flying gravel to the under-cover of the railroad vehicle during operation. In order to prevent this, real-time monitoring of the large under-cover surface of the railroad vehicle is unavoidable. Under the assumption of vehicle application, sensor sensitivities were measured after multiple and prolonged exposure to thermal cycle environment -20⁓60 degrees Celsius). Sensitivity evaluation of paint sensor under environmental conditions was conducted in an aluminum specimen. In results, despite the small variations in sensitivity, we could confirm the applicability of this paint sensor for impact detection even after a severe environmental exposure test

  3. [The implications of the automatic blood pressure monitoring (ABPM) in the type I diabetes].

    Science.gov (United States)

    Cobuz, C

    2009-01-01

    The connection between hypertension and diabetes emerges, in medical practice, from the current belief imposed by the European Society of Cardiology adding to the notion of total cardiovascular risk. An increse in the systolic blood pressure at night time is the first detectable manifestation of the regulation disorders of the blood pressure in type I diabetes. An early increase of the nocturnal blood pressure can play a key role in the detection of the evolution towards diabetic nephropathy. This modification can be a valuable potential marker for the diabetic nephropathy and could provide a reason for treating the high risk patients before the onset of microalbuminuria. The evaluation of the nefropathy risk in the early stages of type I diabetes using Ambulatory Blood Pressure Monitoring (ABPM) method offers the best premisses for preventing the progression of the disease towards microalbuminuria and hypertension.

  4. Characteristic analysis of coupled transmission lines in stripline-type beam position monitor

    International Nuclear Information System (INIS)

    Suwada, T.

    2013-01-01

    Signal transmission characteristics in stripline electrodes of a stripline-type beam position monitor (BPM) are discussed on the basis of a coupled-mode analysis in electromagnetically coupled transmission lines. The physical prospect in the calibration procedure of stripline electrodes is improved in terms of signal transmission characteristics in the frequency domain. It is demonstrated that in the signal transmission with electromagnetic coupling between the stripline electrodes, the magnetic- and electric-coupling parameters play an important role depending upon the spatial configuration and mechanical structure of the stripline electrodes. In this report, a theoretical analysis, and experimental investigation into signal transmission characteristics and performance in a standard stripline-type BPM are described in detail on the basis of a coupled-mode analysis in uniform transmission lines

  5. Monitoring device for shaft oscillation of reactor incorporated-type recycling pump

    International Nuclear Information System (INIS)

    Miyashita, Kaoru; Shibasaki, Kimiyuki.

    1995-01-01

    The present invention concerns monitoring of recycling pump shaft oscillation in a BWR type reactor, which monitors by separating a rotation pulse signal and a shaft oscillation waveform signal obtained in a non-contact type displacement meter. Namely, a threshold value calculation means of a separation processing section takes in original waveform data and selects the maximum value and the minimum value among them. A threshold value is calculated based on the values. An average value of the original waveform data for portions which do not exceed the threshold value is calculated. A first calculation means compares each of the original data with the threshold value, and if the original data are greater than the threshold value, they are outputted as the original data corresponding to the rotation pulse signal. When the original data are smaller than the threshold value, they are outputted as they are as a shaft oscillation waveform signal. On the other hand, a second calculation means calculates an average value for the pulse of the original waveform data corresponding to the rotation pulse signal. An average value of the original waveform data which do not exceed the threshold value are subtracted from the average value, to form the shaft oscillation waveform signal and output the same. (I.S.)

  6. The design and installation of a core discharge monitor for CANDU-type reactors

    International Nuclear Information System (INIS)

    Halbig, J.K.; Monticone, A.C.; Ksiezak, L.; Smiltnieks, V.

    1990-01-01

    A new type of surveillance systems that monitors neutron and gamma radiation in a reactor containment is being installed at the Ontario Hydro Darlington Nuclear Generating Station A, Unit 2. Unlike video or film surveillance that monitors mechanical motion, this system measures fuel-specific radiation emanating from irradiated fuel as it is pushed from the core of CANDU-type reactors. Proof-of-principle measurements have been carried out at Bruce Nuclear Generating Station A, Unit 3. The system uses (γ,n) threshold detectors and ionization detectors. A microprocessor-based electronics package, GRAND-II (Gamma Ray and Neutron Detector electronics package), provides detector bias, preamplifier power, and signal processing. Firmware in the GRAND-2 controls the surveillance activities, including data acquisition and a level of detector authentication, and it handles authenticated communication with a central data logging computer. Data from the GRAND-II are transferred to an MS-DOS-compatible computer and stored. These data are collected and reviewed for fuel-specific radiation signatures from the primary detector and proper ratios of signals from secondary detectors. 5 figs

  7. Study of behaviour of the monitor chambers of a linear accelerator for medical use

    International Nuclear Information System (INIS)

    Brosed, A.; Lopez-Bote, M.A.; Blanco, M.A.; Galvez, M.

    1988-01-01

    An experimental procedure to study the nature and behaviour of the monitor chambers of a linear accelerator for medical use is presented. The procedure has been applied to a Siemens accelerator, Mevatron-77, that has two different types of monitor chambers: sealed for the photon beam and unsealed for the electron ones. As it was expected, no deviations in the dose per monitor unit has been obtained for the photon beam. Variations in the absorbed dose per monitor unit have been observed for the electron beams up to 6% along the working day. Practical solutions compensating this fact are pointed out and the standard recommendations on the control of dose per monitor unit are discussed. (Author)

  8. Monitoring in beeld: een studie naar de doorwerking van monitors in interbestuurlijke relaties

    NARCIS (Netherlands)

    D. de Kool (Dennis)

    2007-01-01

    textabstractMonitoring in the Dutch public sector An increasing stream of monitoring activities has entered the public sector. A lot of different monitors have been implemented in the Netherlands, like the police monitor, drugs monitor, integration monitor and the emancipation monitor. Although

  9. Biological characteristics as a part of pollution monitoring studies

    Digital Repository Service at National Institute of Oceanography (India)

    Nair, V.R.; Govindan, K.

    Ecosystem modifications can be considered as an integral part of any pollution monitoring studies and in such cases community structure/diversity is of prime importance. Considering this advantage of aquatic life, pelagic and benthic communities...

  10. Evaluation of hirst-type spore trap to monitor environmental fungal load in hospital.

    Directory of Open Access Journals (Sweden)

    Cédric Dananché

    Full Text Available The main purpose was to validate the use of outdoor-indoor volumetric impaction sampler with Hirst-type spore traps (HTSTs to continuously monitor fungal load in order to prevent invasive fungal infections during major structural work in hospital settings. For 4 weeks, outdoor fungal loads were quantified continuously by 3 HTSTs. Indoor air was sampled by both HTST and viable impaction sampler. Results were expressed as particles/m3 (HTST or colony-forming units (CFU/m3 (biocollector. Paired comparisons by day were made with Wilcoxon's paired signed-rank test or paired Student's t-test as appropriate. Paired airborne spore levels were correlated 2 by 2, after log-transformation with Pearson's cross-correlation. Concordance was calculated with kappa coefficient (κ. Median total fungal loads (TFLs sampled by the 3 outdoor HTSTs were 3,025.0, 3,287.5 and 3,625.0 particles/m3 (P = 0.6, 0.6 and 0.3.-Concordance between Aspergillaceae fungal loads (AFLs, including Aspergillus spp. + Penicillium spp. was low (κ = 0.2. A low positive correlation was found between TFLs sampled with outdoor HTST and indoor HTST with applying a 4-hour time lag, r = 0.30, 95% CI (0.23-0.43, P<0.001. In indoor air, Aspergillus spp. were detected by the viable impaction sampler on 63.1% of the samples, whereas AFLs were found by HTST-I on only 3.6% of the samples. Concordance between Aspergillus spp. loads and AFLs sampled with the 2 methods was very low (κ = 0.1. This study showed a 4-hour time lag between increase of outdoor and indoor TFLs, possibly due to insulation and aeraulic flow of the building. Outdoor HTSTs may permit to quickly identify (after 48 hours time periods with high outdoor fungal loads. An identified drawback is that a too low sample area read did not seem to enable detection of Aspergillaceae spores efficiently. Indoor HTSTs may not be recommended at this time, and outdoor HTSTs need further study. Air sampling by viable impaction sampler remains the

  11. Evaluation of hirst-type spore trap to monitor environmental fungal load in hospital.

    Science.gov (United States)

    Dananché, Cédric; Gustin, Marie-Paule; Cassier, Pierre; Loeffert, Sophie Tiphaine; Thibaudon, Michel; Bénet, Thomas; Vanhems, Philippe

    2017-01-01

    The main purpose was to validate the use of outdoor-indoor volumetric impaction sampler with Hirst-type spore traps (HTSTs) to continuously monitor fungal load in order to prevent invasive fungal infections during major structural work in hospital settings. For 4 weeks, outdoor fungal loads were quantified continuously by 3 HTSTs. Indoor air was sampled by both HTST and viable impaction sampler. Results were expressed as particles/m3 (HTST) or colony-forming units (CFU)/m3 (biocollector). Paired comparisons by day were made with Wilcoxon's paired signed-rank test or paired Student's t-test as appropriate. Paired airborne spore levels were correlated 2 by 2, after log-transformation with Pearson's cross-correlation. Concordance was calculated with kappa coefficient (κ). Median total fungal loads (TFLs) sampled by the 3 outdoor HTSTs were 3,025.0, 3,287.5 and 3,625.0 particles/m3 (P = 0.6, 0.6 and 0.3).-Concordance between Aspergillaceae fungal loads (AFLs, including Aspergillus spp. + Penicillium spp.) was low (κ = 0.2). A low positive correlation was found between TFLs sampled with outdoor HTST and indoor HTST with applying a 4-hour time lag, r = 0.30, 95% CI (0.23-0.43), PHTST-I on only 3.6% of the samples. Concordance between Aspergillus spp. loads and AFLs sampled with the 2 methods was very low (κ = 0.1). This study showed a 4-hour time lag between increase of outdoor and indoor TFLs, possibly due to insulation and aeraulic flow of the building. Outdoor HTSTs may permit to quickly identify (after 48 hours) time periods with high outdoor fungal loads. An identified drawback is that a too low sample area read did not seem to enable detection of Aspergillaceae spores efficiently. Indoor HTSTs may not be recommended at this time, and outdoor HTSTs need further study. Air sampling by viable impaction sampler remains the reference tool for quantifying fungal contamination of indoor air in hospitals.

  12. Suitability study of using a coincidence monitor for room air radioactivity monitoring in a PET center

    International Nuclear Information System (INIS)

    Roellig, D.; Reichelt, C.; Iwatschenko-Borho, M.

    2001-01-01

    The application of radioactive nuclides in medicine may cause as well radioactive exposure of personnel (Medical Technical Assistants). In the present case the exposure of personnel in the area of medical positron-emission tomography (PET) within the Research Center of Rossendorf due to exhalation of the injected activity by the patient shall be investigated. For this purpose it is necessary to measure the activity concentration of the room air. Conventional methods such as collecting samples on special filters are not suitable due to the short half-life time of the used nuclides. Standard type continuous monitors are hardly suitable as well, because the injected activity of the patient and various radioactive sources required for the calibration of the PET-Camera produce an increased gamma background. In order to eliminate these disturbing influences a monitor has been constructed which uses CCM (cobalt coincidence method) developed by the company Thermo Eberline ESM. This method is specially suitable because upon each radioactive decay of PET nuclides positrons are emitted which in turn annihilate via the simultaneous emission of two 511 keV gamma quanta under an angle of 180 . The air to be measured is sucked through a cavity with two scintillation detectors on opposite sides. The coincident pulses produced by annihilating positrons inside the cavity are counted by a suitable electronic. Gamma quanta from outside the cavity can produce a pulse only in one detector and are rejected. Therefore no heavy lead shielding is required. Besides the mechanical construction of the monitor optimization and calibration for different PET-nuclides had to be performed. Special attention was paid to the sampling system. The air intake had to be close to the breathing zone of the MTA. The hose to the monitor had to be as short as possible. The target of the work was to design a model for an industrial monitor. (orig.) [de

  13. Monitored Retrievable Storage conceptual system studies: closed-cycle vault

    International Nuclear Information System (INIS)

    Washington, J.A.; Ganley, J.T.

    1984-02-01

    The Nuclear Waste Policy Act of 1982 requires the DOE to submit a proposal to Congress by June 1985 for the construction of one or more Monitored Retrieval Storage (MRS) facilities. In response, the DOE initiated studies to develop system descriptions and cost estimates for preconceptual designs of storage concepts suitable for use at MRS facilities. This report provides a system description and cost estimates for a Closed-Cycle Vault (CCV) MRS facility. The facility description is divided into four parts: (1) the R and H area, (2) the interface facility, (3) the on-site transport system, and (4) the storage system. The MRS facility has been designed to meet handling rates of 1800 and 3000 MTU/yr. The corresponding peak inventories are 15,000 and 72,000 MTU. Three types of cases were considered, based on the material to be stored: (1) Spent fuel only; (2) HLW and TRU waste; and (3) HLW only. For each of these three types, a cost estimate was done for a 15,000 and a 72,000 MTU facility, resulting in six different cost estimates. Section 4 presents the cost analysis of the CCV MRS system. Tables 4-2 through 4-7 give the construction or capital costs for the six cases. Tables 4-8 through 4-13 show the total discounted life-cycle costs for each of the six cases. These life-cycle costs include operating and decommissioning costs. These tables also show the time distribution of the capital costs. Table 2-1 summarizes the capital, operating, and discounted costs for the six cases studied. 2 references, 15 figures, 18 tables

  14. Feasibility study of patient motion monitoring using tactile array sensor

    International Nuclear Information System (INIS)

    Kim, Tae Ho; Kang, Seong Hee; Kim, Dong Su; Cho, Min Seok; Kim, Kyeong Hyeon; Suh, Tae Suk; Kim, Si Yong

    2014-01-01

    The aim of this study is to evaluate patient pretreatment set-up error and intra-fraction motion using the tactile array sensors (Pressure Profile Systems Inc, Los Angeles, CA) which could measure distributed pressure profiles along the contacting surface and to check a feasibility of the sensor (tactile array sensor) in the patient motion monitoring. Laser alignment and optical camera based monitoring system are very useful for reduce patient set-up error but these systems could not monitor the blind area like patient's back position. Actually after patient alignment using laser or optical monitoring system, it was assumed that there is no error in the patient's back position (pressure profile distribution). But if an error occurs in the patient's back position, it will affect the radiation therapy accuracy. In spite of optical motion monitoring or using the immobilization tool, distributed pressure profiles of patient's back position was changed during inter and intra-fraction. For more accurate patient set-up, blind area (patient's back) monitoring was necessary. We expect that the proposed method will be very useful for make up for the weakness of optical monitoring method

  15. Feasibility study of patient motion monitoring using tactile array sensor

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Tae Ho; Kang, Seong Hee; Kim, Dong Su; Cho, Min Seok; Kim, Kyeong Hyeon; Suh, Tae Suk [Dept. of Biomedical Engineering, Research Institute of Biomedical Engineering, the Catholic University of Korea, Seoul (Korea, Republic of); Kim, Si Yong [Dept. of Radiation Oncology, Virginia Commonwealth University, Richmond (United States)

    2014-11-15

    The aim of this study is to evaluate patient pretreatment set-up error and intra-fraction motion using the tactile array sensors (Pressure Profile Systems Inc, Los Angeles, CA) which could measure distributed pressure profiles along the contacting surface and to check a feasibility of the sensor (tactile array sensor) in the patient motion monitoring. Laser alignment and optical camera based monitoring system are very useful for reduce patient set-up error but these systems could not monitor the blind area like patient's back position. Actually after patient alignment using laser or optical monitoring system, it was assumed that there is no error in the patient's back position (pressure profile distribution). But if an error occurs in the patient's back position, it will affect the radiation therapy accuracy. In spite of optical motion monitoring or using the immobilization tool, distributed pressure profiles of patient's back position was changed during inter and intra-fraction. For more accurate patient set-up, blind area (patient's back) monitoring was necessary. We expect that the proposed method will be very useful for make up for the weakness of optical monitoring method.

  16. The use of industrial type control and monitoring components for a large fusion experiment

    International Nuclear Information System (INIS)

    Hemming, O.N.; Manduchi, G.; Luchetta, A.; Schmidt, V.; Vitturi, S.

    1994-01-01

    RFX is one of the large nuclear fusion experiments within the framework of the co-ordinated nuclear fusion research programme of the European Community. During the control system design phase in 1986, the increase in power and flexibility of industrial type programmable controllers lead to the decision for a complete physical split of control, monitoring and data acquisition functions according to speed requirements, allowing the exploitation of the relative advantages of both CAMAC and programmable controllers. The 'slow' control and monitoring functions (for about 4000 digital and 200 analog I/O signals with scanning times of similar 1 second) have been implemented using a series of networked industrial PLCs and personal computers. This has allowed us to choose from a wide range of off-the-shelf hardware and software components for the plant interface and to utilize specialized expertise from the industrial field for the application software implementation. The paper gives the expectations and results gained from this design choice and how it has influenced the decisions for the evolution of the system over the next few years with the utilization of new industrial hardware components. Details are also given regarding the system integration (via the Ethernet network) with the VAX-based CAMAC frontend fast control and data-acquisition system. ((orig.))

  17. Hypoglycemia in type 2 diabetes patients treated with insulin: the advantages of continuous glucose monitoring

    Directory of Open Access Journals (Sweden)

    Vadim Valer'evich Klimontov

    2014-03-01

    Full Text Available Aims.  To determine the incidence and risk factors for hypoglycemia in elderly insulin-treated type 2 diabetes mellitus (T2DM patients by means of continuous glucose monitoring (CGM. Materials and Methods.  We observed seventy-six hospitalized patients with T2DM, aged 65 to 79 years. Treatment with basal insulin (n=36, premixed insulin (n=12 or basal-bolus insulin regimen (n=28 was followed by metformin (n=44, glimepiride (n=14 and dipeptidyl peptidase-4 inhibitors (n=14. 2-days CGM with retrospective data analysis was performed in all patients. During CGM, three fasting and three 2-h postprandial finger-prick glucose values were obtained daily with portable glucose meter. Results.  Hypoglycemia (identified as blood glucose

  18. Hypoglycemic Exposure and Risk of Asymptomatic Hypoglycemia in Type 1 Diabetes assessed by Continuous Glucose Monitoring

    DEFF Research Database (Denmark)

    Henriksen, Marie Moth; Andersen, Henrik Ullits; Thorsteinsson, Birger

    2018-01-01

    : To explore the association between hypoglycemic exposure and proportion of asymptomatic hypoglycemia and relation to risk of severe hypoglycemia. Design: Prospective observational trial. Setting: Outpatient clinic. Patients: 153 unselected subjects with type 1 diabetes mellitus (T1D). Intervention: Six days...... of blinded continuous glucose monitoring (CGM) and recording of hypoglycemia symptoms. Main Outcome Measure: Proportion of asymptomatic hypoglycemic events (≤70 mg/dl). Results: Patients were grouped by the number of hypoglycemic events during the recording period (group 1: 1 event, group 2: 2-3 events...... positively associated with risk of severe hypoglycemia (incidence rate ratio (IRR) 1.3 (95% CI 1.1-1.5); p=0.003). Group 4 consisted of patients characterized by classical risk factors of severe hypoglycemia (longer duration of diabetes, lower HbA1c and more frequent impaired awareness of hypoglycemia...

  19. Association of glycaemic variability evaluated by continuous glucose monitoring with diabetic peripheral neuropathy in type 2 diabetic patients.

    Science.gov (United States)

    Hu, Yu-Ming; Zhao, Li-Hua; Zhang, Xiu-Lin; Cai, Hong-Li; Huang, Hai-Yan; Xu, Feng; Chen, Tong; Wang, Xue-Qin; Guo, Ai-Song; Li, Jian-An; Su, Jian-Bin

    2018-05-01

    Diabetic peripheral neuropathy (DPN), a common microvascular complication of diabetes, is linked to glycaemic derangements. Glycaemic variability, as a pattern of glycaemic derangements, is a key risk factor for diabetic complications. We investigated the association of glycaemic variability with DPN in a large-scale sample of type 2 diabetic patients. In this cross-sectional study, we enrolled 982 type 2 diabetic patients who were screened for DPN and monitored by a continuous glucose monitoring (CGM) system between February 2011 and January 2017. Multiple glycaemic variability parameters, including the mean amplitude of glycaemic excursions (MAGE), mean of daily differences (MODD), standard deviation of glucose (SD), and 24-h mean glucose (24-h MG), were calculated from glucose profiles obtained from CGM. Other possible risks for DPN were also examined. Of the recruited type 2 diabetic patients, 20.1% (n = 197) presented with DPN, and these patients also had a higher MAGE, MODD, SD, and 24-h MG than patients without DPN (p diabetic duration, HOMA-IR, and hemoglobin A1c (HbA1c) were found to be independent contributors to DPN, and the corresponding odds ratios (95% confidence interval) were 4.57 (3.48-6.01), 1.10 (1.03-1.17), 1.24 (1.09-1.41), and 1.33 (1.15-1.53), respectively. Receiver operating characteristic analysis indicated that the optimal MAGE cutoff value for predicting DPN was 4.60 mmol/L; the corresponding sensitivity was 64.47%, and the specificity was 75.54%. In addition to conventional risks including diabetic duration, HOMA-IR and HbA1c, increased glycaemic variability assessed by MAGE is a significant independent contributor to DPN in type 2 diabetic patients.

  20. A Versatile Vector for In Vivo Monitoring of Type I Interferon Induction and Signaling.

    Directory of Open Access Journals (Sweden)

    Estanislao Nistal-Villan

    Full Text Available Development of reporter systems for in vivo examination of IFN-β induction or signaling of type I interferon (IFN-I pathways is of great interest in order to characterize biological responses to different inducers such as viral infections. Several reporter mice have been developed to monitor the induction of both pathways in response to different agonists. However, alternative strategies that do not require transgenic mice breeding have to date not been reported. In addition, detection of these pathways in vivo in animal species other than mice has not yet been addressed. Herein we describe a simple method based on the use of an adeno-associated viral vector (AAV8-3xIRF-ISRE-Luc containing an IFN-β induction and signaling-sensitive promoter sequence controlling the expression of the reporter gene luciferase. This vector is valid for monitoring IFN-I responses in vivo elicited by diverse stimuli in different organs. Intravenous administration of the vector in C57BL/6 mice and Syrian hamsters was able to detect activation of the IFN pathway in the liver upon systemic treatment with different pro-inflammatory agents and infection with Newcastle disease virus (NDV. In addition, intranasal instillation of AAV8-3xIRF-ISRE-Luc showed a rapid and transient IFN-I response in the respiratory tract of mice infected with the influenza A/PR8/34 virus lacking the NS1 protein. In comparison, this response was delayed and exacerbated in mice infected with influenza A/PR/8 wild type virus. In conclusion, the AAV8-3xIRF-ISRE-Luc vector offers the possibility of detecting IFN-I activation in response to different stimuli and in different animal models with no need for reporter transgenic animals.

  1. Parsimonious model for blood glucose level monitoring in type 2 diabetes patients.

    Science.gov (United States)

    Zhao, Fang; Ma, Yan Fen; Wen, Jing Xiao; DU, Yan Fang; Li, Chun Lin; Li, Guang Wei

    2014-07-01

    To establish the parsimonious model for blood glucose monitoring in patients with type 2 diabetes receiving oral hypoglycemic agent treatment. One hundred and fifty-nine adult Chinese type 2 diabetes patients were randomized to receive rapid-acting or sustained-release gliclazide therapy for 12 weeks. Their blood glucose levels were measured at 10 time points in a 24 h period before and after treatment, and the 24 h mean blood glucose levels were measured. Contribution of blood glucose levels to the mean blood glucose level and HbA1c was assessed by multiple regression analysis. The correlation coefficients of blood glucose level measured at 10 time points to the daily MBG were 0.58-0.74 and 0.59-0.79, respectively, before and after treatment (Pblood glucose levels measured at 6 of the 10 time points could explain 95% and 97% of the changes in MBG before and after treatment. The three blood glucose levels, which were measured at fasting, 2 h after breakfast and before dinner, of the 10 time points could explain 84% and 86% of the changes in MBG before and after treatment, but could only explain 36% and 26% of the changes in HbA1c before and after treatment, and they had a poorer correlation with the HbA1c than with the 24 h MBG. The blood glucose levels measured at fasting, 2 h after breakfast and before dinner truly reflected the change 24 h blood glucose level, suggesting that they are appropriate for the self-monitoring of blood glucose levels in diabetes patients receiving oral anti-diabetes therapy. Copyright © 2014 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved.

  2. Long-Term Spectroscopic Monitoring and Surveys of Early-Type Stars with and without Circumstellar Envelopes

    Directory of Open Access Journals (Sweden)

    Miroshnichenko Anatoly S.

    2017-11-01

    Full Text Available Ongoing studies of different groups of stars result in improving our knowledge of their fundamental parameters and evolutionary status. Also, they result in finding new phases of stellar evolution, which require theoretical explanation. At the same time, availability of large telescopes and sensitivity improvement of detectors shift the focus of many observational programs toward fainter and more distant objects. However, there are still many problems in our understanding of details of stellar evolution which can now be solved with small telescopes and observations of bright stars. Approaching these problems implies conducting surveys of large groups of stars and long-term monitoring of individual objects. In this talk, we present the results of recent international programs of photometric and spectral monitoring of several groups of early-type stars. In particular, we discuss the role of binarity in creation of the Be phenomenon and show examples of recently discovered binary systems as well as the problem of refining fundamental parameters of B and A type supergiants. Special attention will be paid to collaboration with the amateur community and use of échelle spectrographs mounted on small telescopes.

  3. Clinical value of Flash glucose monitoring in patients with type 1 diabetes treated with continuous subcutaneous insulin infusion.

    Science.gov (United States)

    Moreno-Fernandez, Jesus; Pazos-Couselo, Marcos; González-Rodriguez, Maria; Rozas, Pedro; Delgado, Manuel; Aguirre, Miguel; Garcia-Lopez, Jose Manuel

    2018-06-12

    To analyze the clinical impact of the Flash glucose monitoring system in patients with type 1 diabetes mellitus (T1DM) treated with continuous subcutaneous insulin infusion (CSII). A 24-week retrospective cohort study in CSII-treated T1DM patients exposed (1:1) to the Flash glucose monitoring system vs. self-monitoring of capillary blood glucose (SMBG). The primary outcome was the difference in hemoglobin A1c (HbA1c) levels between both groups at the end of the study. Thirty-six patients with a mean age of 38.2 years (range 22-55) and a mean T1DM duration of 20.9±7.8 years, treated with CSII for 7.1±5.4 years, were enrolled into the study. At the end of the study, mean HbA1c levels improved in patients in the Flash group (7.1±0.7 vs. 7.8±1.0, p=0.04). Only the Flash group showed a significant decrease in HbA1c levels of -0.4% (95% CI, -0.6, -0.2; p=0.004) during follow-up. Flash patients captured 93.9% of data through 17.8±9.9 scans daily. In fact, the Flash cohort showed a three-fold increase in daily self-monitoring of glucose, while daily frequency of SMBG decreased during the study (-1.8 tests/24h (95% CI -3, -0.7; p=0.01). No safety issues related to Flash use were recorded. The Flash glucose monitoring system is a novel approach to improve blood glucose control in CSII-treated T1DM patients. Randomized controlled trials are needed to assess the effectiveness of this system in CSII-treated T1DM patients. Copyright © 2018 SEEN y SED. Publicado por Elsevier España, S.L.U. All rights reserved.

  4. Explaining engagement in self-monitoring among participants of the DESMOND Self-monitoring Trial: a qualitative interview study.

    Science.gov (United States)

    Eborall, Helen C; Dallosso, Helen M; McNicol, Sarah; Speight, Jane; Khunti, Kamlesh; Davies, Melanie J; Heller, Simon R

    2015-10-01

    The Diabetes Education and Self-Management for Ongoing and Newly Diagnosed (DESMOND) Self-monitoring Trial reported that people with newly diagnosed type 2 diabetes attending community-based structured education and randomized to self-monitoring of blood glucose (SMBG) or urine monitoring had comparable improvements in biomedical outcomes, but differences in satisfaction with, and continued use of monitoring method, well-being and perceived threat from diabetes. To explore experiences of SMBG and urine monitoring following structured education. We specifically addressed the perceived usefulness of each monitoring method and the associated well-being. Qualitative semi-structured interviews with 18 adults with newly diagnosed type 2 diabetes participating in the DESMOND Self-monitoring Trial (SMBG, N=10; urine monitoring, N=8)~12 months into the trial. Analysis was informed by the constant comparative approach. Interviewees reported SMBG as accurate, convenient and useful. Declining use was explained by having established a pattern of managing blood glucose with less frequent monitoring or lack of feedback or encouragement from health care professionals. Many initially positive views of urine monitoring progressively changed due to perceived inaccuracy, leading some to switch to SMBG. Perceiving diabetes as less serious was attributable to lack of symptoms, treatment with diet alone and-in the urine-monitoring group-consistently negative readings. Urine monitoring also provided less visible evidence of diabetes and of the effect of behaviour on glucose. The findings highlight the importance for professionals of considering patients' preferences when using self-monitoring technologies, including how these change over time, when supporting the self-care behaviours of people with type 2 diabetes. © The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  5. Sensitivity studies for supernovae type Ia

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Thien Tam; Goebel, Kathrin; Reifarth, Rene [Goethe University Frankfurt am Main (Germany); Calder, Alan [SUNY - Department of Physics and Astronomy, New York (United States); Pignatari, Marco [Konkoly Observatory of the Hungarian Academy of Sciences (Hungary); Townsley, Dean [The University of Alabama (United States); Travaglio, Claudia [INAF - Astrophysical Observatory, Turin (Italy); Collaboration: NuGrid collaboration

    2016-07-01

    The NuGrid research platform provides a simulation framework to study the nucleosynthesis in multi-dimensional Supernovae Type Ia models. We use a large network of over 5,000 isotopes and more than 60,000 reactions. The nucleosynthesis is investigated in post-processing simulations with temperature and density profiles, initial abundance distributions and a set of reaction rates as input. The sensitivity of the isotopic abundances to α-, proton-, and neutron-capture reaction, their inverse reactions, as well as fusion reactions were investigated. First results have been achieved for different mass coordinates of the exploding star.

  6. Study of an integrated electronic monitor for neutron fields

    Energy Technology Data Exchange (ETDEWEB)

    Barelaud, B.; Nexon-Mokhtari, F.; Barrau, C.; Decossas, J.L.; Vareille, J.C. [Limoges Univ., 87 (France); Sarrabayrouse, G.J. [CNRS, 31 - Toulouse (France)

    1995-12-31

    The majority of the individual neutron monitors measure incorrectly in a certain energy range (10 keV-500 keV). For electronic devices, this problem is due to their high {gamma} sensitivity. To solve this problem a microelectronic detector design for neutron spectrometry is now being studied at LEPOFI. It is based on the measurement of the total energy which is deposited by {sup 6}Li (n, {alpha}) {sup 3}H or {sup 10}B (n {alpha}) {sup 7}Li reactions in silicon detectors. A new electronic sensor - for example a boron or lithium sandwich device -has been developed in collaboration with LAAS. Specific techniques for silicon sensor coating with boron have been developed and are briefly presented. The response of the detector has been computed using a model and a code developed at LEPOFI. Several parameters have been taken into account in the calculations: the type of layer, its thickness, the characteristics of the detector. The results of these simulations are discussed and calculated pulse height distributions for various designs are presented. The present status of the investigation only concerns thermal neutrons. (author).

  7. Twenty-four-hour variations in blood glucose level in Japanese type 2 diabetes patients based on continuous glucose monitoring.

    Science.gov (United States)

    Hajime, Maiko; Okada, Yosuke; Mori, Hiroko; Otsuka, Takashi; Kawaguchi, Mayuko; Miyazaki, Megumi; Kuno, Fumi; Sugai, Kei; Sonoda, Satomi; Tanaka, Kenichi; Kurozumi, Akira; Narisawa, Manabu; Torimoto, Keiichi; Arao, Tadashi; Tanaka, Yoshiya

    2018-01-01

    High fluctuations in blood glucose are associated with various complications. The correlation between glycated hemoglobin (HbA1c) level and fluctuations in blood glucose level has not been studied in Japanese patients with type 2 diabetes. In the present study, blood glucose profile stratified by HbA1c level was evaluated by continuous glucose monitoring (CGM) in Japanese type 2 diabetes patients. Our retrospective study included 294 patients with type 2 diabetes who were divided by HbA1c level into five groups (≥6.0 to level and CGM data was analyzed. The primary end-point was the difference in blood glucose fluctuations among the HbA1c groups. The mean blood glucose level increased significantly with increasing HbA1c (P trend  levels of maximum blood glucose, minimum blood glucose, each preprandial blood glucose, each postprandial maximum blood glucose, range of increase in postprandial glucose from pre-meal to after breakfast, the area under the blood concentration-time curve >180 mg/dL and percentage of the area under the blood concentration-time curve >180 mg/dL were higher with higher HbA1c. Mean glucose level and pre-breakfast blood glucose level were significant and independent determinants of HbA1c. In Japanese patients treated for type 2 diabetes, the mean amplitude of glycemic excursions did not correlate with HbA1c, making it difficult to assess blood glucose fluctuations using HbA1c. Parameters other than HbA1c are required to evaluate fluctuations in blood glucose level in patients receiving treatment for type 2 diabetes. © 2017 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd.

  8. Illusions of Competence in Monitoring One's Knowledge During Study

    Science.gov (United States)

    Koriat, Asher; Bjork, Robert A.

    2005-01-01

    The monitoring of one's own knowledge during study suffers from an inherent discrepancy between study and test situations: Judgments of learning (JOLs) are made in the presence of information that is absent but solicited during testing. The failure to discount the effects of that information when making JOLs can instill a sense of competence…

  9. Field desorption mass spectroscopy monitoring of changes in hydrocarbon type composition during petroleum biodegradation

    International Nuclear Information System (INIS)

    Huesemann, M.H.

    1995-01-01

    A comprehensive petroleum hydrocarbon characterization procedure involving group type separation, boiling point distribution, and hydrocarbon typing by field desorption mass spectroscopy (FDMS) has been developed to quantify changes in hydrocarbon type composition during bioremediation of petroleum-contaminated soils. FDMS is able to quantify the concentration of hundreds of specific hydrocarbon types based on their respective hydrogen deficiency (z-number) and molecular weight (carbon number). Analytical results from two bioremediation experiments involving soil contaminated with crude oil and motor oil indicate that alkanes and two-ring saturates (naphthenes) were readily biodegradable. In addition, low-molecular-weight hydrocarbons generally were biodegraded to a larger extent than those of high molecular weight. More importantly, it was found that the extent of biodegradation of specific hydrocarbon types was comparable between treatments and appeared to be unaffected by the petroleum contaminant source, soil type, or experimental conditions. It was therefore concluded that in these studies the extent of total petroleum hydrocarbon (TPH) biodegradation is primarily affected by the molecular composition of the petroleum hydrocarbons present in the contaminated soil

  10. Molecular and biochemical biomarkers for diagnosis and therapy monitorization of Niemann-Pick type C patients.

    Science.gov (United States)

    Hammerschmidt, Tatiane Grazieli; de Oliveira Schmitt Ribas, Graziela; Saraiva-Pereira, Maria Luiza; Bonatto, Márcia Polese; Kessler, Rejane Gus; Souza, Fernanda Timm Seabra; Trapp, Franciele; Michelin-Tirelli, Kristiane; Burin, Maira Graeff; Giugliani, Roberto; Vargas, Carmen Regla

    2018-05-01

    Niemann-Pick type C (NP-C), one of 50 inherited lysosomal storage disorders, is caused by NPC protein impairment that leads to unesterified cholesterol accumulation in late endosomal/lysosomal compartments. The clinical manifestations of NP-C include hepatosplenomegaly, neurological and psychiatric symptoms. Current diagnosis for NP-C is based on observation of the accumulated cholesterol in fibroblasts of affected individuals, using an invasive and time expensive test, called Filipin staining. Lately, two metabolites that are markedly increased in NP-C patients are arising as biomarkers for this disease screening: 7-ketocholesterol and cholestane-3β,5α,6β-triol, both oxidized cholesterol products. In this work, we aimed to evaluate the performance of cholestane-3β,5α,6β-triol analysis for the screening and monitoring of NPC patients, correlating it with chitotriosidase levels, Filipin staining and molecular analysis. It was investigated 76 non-treated individuals with NP-C suspicion and also 7 patients with previous NP-C diagnosis under treatment with miglustat, in order to verify the cholestane-3β,5α,6β-triol value as a tool for therapy monitoring. Considering molecular assay as golden standard, it was verified that cholestane-3β,5α,6β-triol analysis presented 88% of sensitivity, 96.08% of specificity, a positive and negative predictive value calculated in 91.67% and 94.23%, respectively, for the diagnosis of NP-C. Chitotriosidase levels were increased in patients with positive molecular analysis for NP-C. For Filipin staining, it was found 1 false positive, 7 false negative and 24 inconclusive cases, showing that this assay has important limitations for NP-C diagnosis. Besides, we found a significant decrease in cholestane-3β,5α,6β-triol concentrations in NP-C patients under therapy with miglustat when compared to non-treated patients. Taken together, the present data show that cholestane-3β,5α,6β-triol analysis has a high potential to be an

  11. Riding Quality Model for Asphalt Pavement Monitoring Using Phase Array Type L-band Synthetic Aperture Radar (PALSAR

    Directory of Open Access Journals (Sweden)

    Kamiya Yoshikazu

    2010-11-01

    Full Text Available There are difficulties associated with near-real time or frequent pavement monitoring, because it is time consuming and costly. This study aimed to develop a binary logit model for the evaluation of highway riding quality, which could be used to monitor pavement conditions. The model was applied to investigate the influence of backscattering values of Phase Array type L-band Synthetic Aperture Radar (PALSAR. Training data obtained during 3–7 May 2007 was used in the development process, together with actual international roughness index (IRI values collected along a highway in Ayutthaya province, Thailand. The analysis showed that an increase in the backscattering value in the HH or the VV polarization indicated the poor condition of the pavement surface and, of the two, the HH polarization is more suitable for developing riding quality evaluation. The model developed was applied to analyze highway number 3467, to demonstrate its capability. It was found that the assessment accuracy of the prediction of the highway level of service was 97.00%. This is a preliminary study of the proposed technique and more intensive investigation must be carried out using ALOS/PALSAR images in various seasons.

  12. Hazards and operability study for the surface moisture monitoring system

    International Nuclear Information System (INIS)

    Board, B.D.

    1996-01-01

    The Hanford Nuclear Reservation Tank Farms' underground waste tanks have been used to store liquid radioactive waste from defense materials production since the 1940's. Waste in certain of the tanks may contain material in the form of ferrocyanide or various organic compounds which could potentially be susceptible to condensed phase chemical reactions. Because of the presence of oxidizing materials (nitrate compounds) and heat sources (radioactive decay and chemical reactions), the ferrocyanide or organic material could potentially fuel a propagating exothermic reaction with undesirable consequences. Analysis and experiments indicate that the reaction propagation and/or initiation may be prevented by the presence of sufficient moisture in the waste. Because the reaction would probably be initiated at the surface of the waste, evidence of sufficient moisture concentration would help provide evidence that the tank waste can continue to be safely stored. The Surface Moisture Measurement System (SMMS) was developed to collect data on the surface moisture in the waste by inserting two types of probes (singly) into a waste tank-a neutron probe and an electromagnetic inductance (EMI) probe. The sensor probes will be placed on the surface of the waste utilizing a moveable deployment arm to lower them through an available riser. The movement of the SMMS within the tank will be monitored by a camera lowered through an adjacent riser. The SMMS equipment is the subject of this study. Hazards and Operability Analysis (HAZOP) is a systematic technique for assessing potential hazards and/or operability problems for a new activity. It utilizes a multidiscipline team of knowledgeable individuals in a systematic brainstorming effort. The results of this study will be used as input to an Unreviewed Safety Question determination

  13. A simple and powerful XY-Type current monitor for 30 MeV IPEN/CNEN-SP cyclotron

    Energy Technology Data Exchange (ETDEWEB)

    Barcellos, Henrique; Matsuda, Hylton; Sumyia, Luiz Carlos do A.; Junqueira, Fernando de C.; Costa, Osvaldo L. da, E-mail: hbolivei@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2017-11-01

    A water-cooled XY-type current monitor was designed and built in the Cyclotrons Laboratory of the Nuclear and Energy Research Institute (IPEN). It is a very simple design and easily adaptable to the cyclotron beam lines. Tests were done demonstrating to be an instrument of great assistance in proton beam position along beam transport line and target port. Nowadays the XY-type current monitor has been widely used in {sup 18}F-FDG routine productions, employing irradiation system which were originally designed for productions on 18 MeV cyclotron accelerator only, however, applying the XY-type current monitor the target port may be exchanged between the 30 MeV and 18 MeV cyclotrons and the observed results are in perfect agreement with expected. (author)

  14. Analytical & Experimental Study of Radio Frequency Cavity Beam Profile Monitor

    Energy Technology Data Exchange (ETDEWEB)

    Balcazar, Mario D. [Fermilab; Yonehara, Katsuya [Fermilab

    2017-10-22

    The purpose of this analytical and experimental study is multifold: 1) To explore a new, radiation-robust, hadron beam profile monitor for intense neutrino beam applications; 2) To test, demonstrate, and develop a novel gas-filled Radio-Frequency (RF) cavity to use in this monitoring system. Within this context, the first section of the study analyzes the beam distribution across the hadron monitor as well as the ion-production rate inside the RF cavity. Furthermore a more effecient pixel configuration across the hadron monitor is proposed to provide higher sensitivity to changes in beam displacement. Finally, the results of a benchtop test of the tunable quality factor RF cavity will be presented. The proposed hadron monitor configuration consists of a circular array of RF cavities located at a radial distance of 7cm { corresponding to the standard deviation of the beam due to scatering { and a gas-filled RF cavity with a quality factor in the range 400 - 800.

  15. Monitoring with MonAMI: a case study

    Energy Technology Data Exchange (ETDEWEB)

    Millar, A P; Stewart, G A [Department of Physics and Astronomy, University of Glasgow, University Avenue, Glasgow, G12 8QQ (United Kingdom); Cowan, G A [Department of Physics, University of Edinburgh, Edinburgh (United Kingdom)], E-mail: p.millar@physics.gla.ac.uk

    2008-07-15

    Computing resources in HEP are increasingly delivered utilising grid technologies, which presents new challenges in terms of monitoring. Monitoring involves the flow of information between different communities: the various resource-providers and the different user communities. The challenge is providing information so everyone can find what they need: from the local site administrators, regional operational centres through to end-users. To meet this challenge, MonAMI was developed. MonAMI aims to be a universal sensor framework with a plugin architecture. This plugin structure allows flexibility in what is monitored and how the gathered information is reported. MonAMI supports gathering statistics from many standard daemons, such as MySQL and Apache, and system data, such as network sockets and memory consumption. The gathered data can be sent to many monitoring systems, including Ganglia, Nagios, MonALISA and R-GMA. This flexibility allows MonAMI to be integrated into whatever monitoring system is being used. This avoids the current duplication of sensors and allows the gathered statistics to be presented within a greater diversity of monitoring systems. Using the MonAMI framework, sensors have been developed for the DPM and dCache storage systems, both common at HEP grid centres. The development of these tools specifically to tackle the challenges of high availability storage is described. We illustrate how MonAMI's architecture allows a single sensor to both deliver long term trend information and to trigger alarms in abnormal conditions. The use of MonAMI within the ScotGrid distributed Tier-2 is examined as a case study, illustrating both the ease with which MonAMI integrates into existing systems and helps provide a framework for extending monitoring where necessary.

  16. Monitoring with MonAMI: a case study

    International Nuclear Information System (INIS)

    Millar, A P; Stewart, G A; Cowan, G A

    2008-01-01

    Computing resources in HEP are increasingly delivered utilising grid technologies, which presents new challenges in terms of monitoring. Monitoring involves the flow of information between different communities: the various resource-providers and the different user communities. The challenge is providing information so everyone can find what they need: from the local site administrators, regional operational centres through to end-users. To meet this challenge, MonAMI was developed. MonAMI aims to be a universal sensor framework with a plugin architecture. This plugin structure allows flexibility in what is monitored and how the gathered information is reported. MonAMI supports gathering statistics from many standard daemons, such as MySQL and Apache, and system data, such as network sockets and memory consumption. The gathered data can be sent to many monitoring systems, including Ganglia, Nagios, MonALISA and R-GMA. This flexibility allows MonAMI to be integrated into whatever monitoring system is being used. This avoids the current duplication of sensors and allows the gathered statistics to be presented within a greater diversity of monitoring systems. Using the MonAMI framework, sensors have been developed for the DPM and dCache storage systems, both common at HEP grid centres. The development of these tools specifically to tackle the challenges of high availability storage is described. We illustrate how MonAMI's architecture allows a single sensor to both deliver long term trend information and to trigger alarms in abnormal conditions. The use of MonAMI within the ScotGrid distributed Tier-2 is examined as a case study, illustrating both the ease with which MonAMI integrates into existing systems and helps provide a framework for extending monitoring where necessary

  17. Identification of novel biomarkers to monitor β-cell function and enable early detection of type 2 diabetes risk.

    Directory of Open Access Journals (Sweden)

    Kirstine J Belongie

    Full Text Available A decline in β-cell function is a prerequisite for the development of type 2 diabetes, yet the level of β-cell function in individuals at risk of the condition is rarely measured. This is due, in part, to the fact that current methods for assessing β-cell function are inaccurate, prone to error, labor-intensive, or affected by glucose-lowering therapy. The aim of the current study was to identify novel circulating biomarkers to monitor β-cell function and to identify individuals at high risk of developing β-cell dysfunction. In a nested case-control study from the Relationship between Insulin Sensitivity and Cardiovascular disease (RISC cohort (n = 1157, proteomics and miRNA profiling were performed on fasting plasma samples from 43 individuals who progressed to impaired glucose tolerance (IGT and 43 controls who maintained normal glucose tolerance (NGT over three years. Groups were matched at baseline for age, gender, body mass index (BMI, insulin sensitivity (euglycemic clamp and β-cell glucose sensitivity (mathematical modeling. Proteomic profiling was performed using the SomaLogic platform (Colorado, USA; miRNA expression was performed using a modified RT-PCR protocol (Regulus Therapeutics, California, USA. Results showed differentially expressed proteins and miRNAs including some with known links to type 2 diabetes, such as adiponectin, but also novel biomarkers and pathways. In cross sectional analysis at year 3, the top differentially expressed biomarkers in people with IGT/ reduced β-cell glucose sensitivity were adiponectin, alpha1-antitrypsin (known to regulate adiponectin levels, endocan, miR-181a, miR-342, and miR-323. At baseline, adiponectin, cathepsin D and NCAM.L1 (proteins expressed by pancreatic β-cells were significantly lower in those that progressed to IGT. Many of the novel prognostic biomarker candidates were within the epithelial-mesenchymal transition (EMT pathway: for example, Noggin, DLL4 and miR-181a. Further

  18. Monitoring of fetuses with intrauterine growth restriction: a longitudinal study

    NARCIS (Netherlands)

    Hecher, K.; Bilardo, C. M.; Stigter, R. H.; Ville, Y.; Hackelöer, B. J.; Kok, H. J.; Senat, M. V.; Visser, G. H.

    2001-01-01

    To describe the time sequence of changes in fetal monitoring variables in intrauterine growth restriction and to correlate these findings with fetal outcome at delivery. This was a prospective longitudinal observational multicenter study on 110 singleton pregnancies with growth-restricted fetuses

  19. Study of the EAR.620 aerosol monitor survival

    International Nuclear Information System (INIS)

    Morisset, A.; Sciorella, G.; Chivu, D.; Meriaux, P.; Pagel, M.

    1976-01-01

    The disappearance of different electronic components on the European professional market was likely to create a very serious problem for the maintenance of health physics instrumentation existing at CEA. The present report is a study of the conditions of assurance of the survival of the air contamination monitor EAR.620 up to 1980 [fr

  20. Vessel Monitoring Systems Study. Volume I - Technical Analysis.

    Science.gov (United States)

    1980-09-01

    In the Port and Tanker Safety Act of 1978 the U.S. Conress directed the Department of Transportation to performa a study on the desirability and feasibility of a shore-station system for monitoring vessels (including fishing vessels)offshore within t...

  1. Learning from case studies and monitoring of Dutch tunnel projects

    NARCIS (Netherlands)

    Korff, M.

    2017-01-01

    Individuals and project-based organisations in the construction industry can learn in a (more) systematic way from case studies and the monitoring of underground construction works. Underground construction projects such as tunnels and excavations suffer as much or more from failure costs

  2. Challenges of monitoring reproductive health services: a case study ...

    African Journals Online (AJOL)

    Challenges of monitoring reproductive health services: a case study of antenatal clinics in Kinondoni municipality, Dar Es Salaam. ... was descriptive cross sectional employing both qualitative and quantitative methods. The sample population included nurse-midwives who manage ANC clinics in Kinondoni Municipality.

  3. Design of the Monitored Occlusion Treatment of Amblyopia Study (MOTAS)

    OpenAIRE

    Stewart, C E; Fielder, A R; Stephens, D A; Moseley, M J

    2002-01-01

    Background/aims: The effectiveness of occlusion therapy for the treatment of amblyopia is a research priority. The authors describe the design of the Monitored Occlusion Treatment for Amblyopia Study (MOTAS) and its methodology. MOTAS will determine the dose-response relation for occlusion therapy as a function of age and category of amblyopia.

  4. Monitoring dental erosion by colour measurement : An in vitro study

    NARCIS (Netherlands)

    Krikken, J. B.; Zijp, J. R.; Huysmans, M. C. D. N. J. M.

    Objectives: The aim of this study was to develop a method to monitor dental erosion by evaluation of the colour change of teeth as a function of enamel loss, and to evaluate the reproducibility of the method used. Methods: Light reflectance spectra of 12 extracted human incisors were measured using

  5. Construction monitoring constraints and challenges:A feasibility study

    OpenAIRE

    Fidler, Paul; Vardanega, Paul J; Long, Peter; Webb, Graham; Stehle, John; Middleton, Campbell

    2013-01-01

    This paper presents a study of the constraints and challenges faced by the authors when invited to study the feasibility of developing a monitoring system to provide specific information sought by the designer and contractor during the construction of the new 225m high, 48 storey steel-framed Leadenhall Building, located at 122 Leadenhall Street in London. The original goal of the study was to develop a system to assist with the active alignment of the building during construction, a key aim ...

  6. Cost calculation for a flash glucose monitoring system for UK adults with type 1 diabetes mellitus receiving intensive insulin treatment.

    Science.gov (United States)

    Hellmund, Richard; Weitgasser, Raimund; Blissett, Deirdre

    2018-04-01

    To estimate the costs associated with a flash glucose monitoring system as a replacement for routine self-monitoring of blood glucose (SMBG) in patients with type 1 diabetes mellitus (T1DM) using intensive insulin, from a UK National Health Service (NHS) perspective. The base-case cost calculation was created using the maximum frequency of glucose monitoring recommended by the 2015 National Institute for Health and Care Excellence guidelines (4-10 tests per day). Scenario analyses considered SMBG at the frequency observed in the IMPACT clinical trial (5.6 tests per day) and at the frequency of flash monitoring observed in a real-world analysis (16 tests per day). A further scenario included potential costs associated with severe hypoglycaemia. In the base case, the annual cost per patient using flash monitoring was £234 (19%) lower compared with routine SMBG (10 tests per day). In scenario analyses, the annual cost per patient of flash monitoring compared with 5.6 and 16 SMBG tests per day was £296 higher and £957 lower, respectively. The annual cost of severe hypoglycaemia for flash monitoring users was estimated to be £221 per patient, compared with £428 for routine SMBG users (based on 5.6 tests/day), corresponding to a reduction in costs of £207. The flash monitoring system has a modest impact on glucose monitoring costs for the UK NHS for patients with T1DM using intensive insulin. For people requiring frequent tests, flash monitoring may be cost saving, especially when taking into account potential reductions in the rate of severe hypoglycaemia. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

  7. Monitoring system for gamma radiation of porch type for vehicles; Sistema de monitoreo de radiacion gamma tipo portal para vehiculos

    Energy Technology Data Exchange (ETDEWEB)

    Vazquez C, R.M.; Molina, G.; Gutierrez O, E.; Ramirez J, F.J.; Garcia H, J.M.; Aguilar B, M.A.; Vilchis P, A.E.; Cruz E, P.; Torres B, M.A. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)

    2005-07-01

    A monitoring system of gamma radiation for vehicles of the porch type developed in the ININ is presented. This system carries out the radiological monitoring of the vehicles in continuous form, detecting the bottom radiological environment and the presence of nuclear material transported in vehicles. The vehicles are monitored while they pass to low speed through the porch. The detectors are plastic scintillators of great volume that allow high sensibility detection. The arrangement of detecting is interconnected in net, and the data are concentrated on a personal computer whose interface man-machine can be accessed from any personal computer connected to Internet. The system monitoring in real time with options of sampling times from 50 ms configurable up to 500 ms. (Author)

  8. A study of the NRPB fast neutron personal monitoring service

    International Nuclear Information System (INIS)

    Bartlett, D.T.; Knight, A.; Marshall, T.O.

    1975-10-01

    The NRPB Fast Neutron Personal Monitoring Service has been reviewed and modifications have been, or are being, introduced to improve the accuracy and reliability of the nuclear emulsion dosemeter employed by the Service. This report presents the conclusions of the study. Experimental results of the investigations undertaken in the course of this study, together with full details of the dosemeter and Service, are appended. (author)

  9. Real-time continuous glucose monitoring during labour and delivery in women with Type 1 diabetes — observations from a randomized controlled trial

    DEFF Research Database (Denmark)

    Cordua, S; Secher, A L; Ringholm, L

    2013-01-01

    To explore whether real-time continuous glucose monitoring during labour and delivery supplementary to hourly self-monitored plasma glucose in women with Type 1 diabetes reduces the prevalence of neonatal hypoglycaemia.......To explore whether real-time continuous glucose monitoring during labour and delivery supplementary to hourly self-monitored plasma glucose in women with Type 1 diabetes reduces the prevalence of neonatal hypoglycaemia....

  10. Mathematical geology studies of deposit prospect types

    International Nuclear Information System (INIS)

    Liu Guangping

    1998-08-01

    Exact certainty prospect type of uranium deposit, not only can assure the quality of deposit prospects, but also increase economic benefits. Based on the standard of geological prospect of uranium deposit, the author introduces a method of Fuzzy Synthetical Comment for dividing prospect type of uranium deposit. The practical applications demonstrate that the regression accuracy, discriminated by Zadeh operator, of 15 known deposits is 100%

  11. Continuous Glucose Monitoring Can Uncover Mistakes in Self-Treatment of Hypoglycemia in Patients with Type I Diabetes Mellitus

    Czech Academy of Sciences Publication Activity Database

    Brož, J.; Urbanová, J.; Janíčková Žďárská, D.; Doničová, V.; Brabec, Marek

    2014-01-01

    Roč. 63, Supplement 1 (2014), A221-A221 ISSN 0012-1797. [American Diabetes Association. Scientific Sessions /74./. 13.06.2014-17.06.2014, San Francisco] Institutional support: RVO:67985807 Keywords : continuous monitoring * type I diabetes * semiparametric modeling Subject RIV: FB - Endocrinology, Diabetology, Metabolism, Nutrition

  12. Continuous Glucose Monitoring Can Uncover Mistakes in Self-Treatment of Hypoglycemia in Patients with Type I Diabetes Mellitus

    Czech Academy of Sciences Publication Activity Database

    Brož, J.; Urbanová, J.; Janíčková Žďárská, D.; Doničová, V.; Brabec, Marek

    2014-01-01

    Roč. 16, Supplement 1 (2014), A35-A35 ISSN 1520-9156. [American Diabetes Association. Scientific Sessions /74./. 13.06.2014-17.06.2014, San Francisco] Institutional support: RVO:67985807 Keywords : continuous monitoring * type I diabetes * semiparametric modeling Subject RIV: FB - Endocrinology, Diabetology, Metabolism, Nutrition

  13. Using Smartphones to Monitor Bipolar Disorder Symptoms: A Pilot Study.

    Science.gov (United States)

    Beiwinkel, Till; Kindermann, Sally; Maier, Andreas; Kerl, Christopher; Moock, Jörn; Barbian, Guido; Rössler, Wulf

    2016-01-06

    Relapse prevention in bipolar disorder can be improved by monitoring symptoms in patients' daily life. Smartphone apps are easy-to-use, low-cost tools that can be used to assess this information. To date, few studies have examined the usefulness of smartphone data for monitoring symptoms in bipolar disorder. We present results from a pilot test of a smartphone-based monitoring system, Social Information Monitoring for Patients with Bipolar Affective Disorder (SIMBA), that tracked daily mood, physical activity, and social communication in 13 patients. The objective of this study was to investigate whether smartphone measurements predicted clinical symptoms levels and clinical symptom change. The hypotheses that smartphone measurements are (1) negatively related to clinical depressive symptoms and (2) positively related to clinical manic symptoms were tested. Clinical rating scales were administered to assess clinical depressive and manic symptoms. Patients used a smartphone with the monitoring app for up to 12 months. Random-coefficient multilevel models were computed to analyze the relationship between smartphone data and externally rated manic and depressive symptoms. Overall clinical symptom levels and clinical symptom changes were predicted by separating between-patient and within-patient effects. Using established clinical thresholds from the literature, marginal effect plots displayed clinical relevance of smartphone data. Overall symptom levels and change in clinical symptoms were related to smartphone measures. Higher overall levels of clinical depressive symptoms were predicted by lower self-reported mood measured by the smartphone (beta=-.56, Psmartphone (ie, cell tower movements: beta=-.11, P=.03). Higher overall levels of clinical manic symptoms were predicted by lower physical activity on the smartphone (ie, distance travelled: beta=-.37, Psmartphone (beta=-.17, Psmartphone measurements, but not all smartphone measures predicted the occurrence of

  14. Blood glucose monitoring and glycemic control in adolescents with type 1 diabetes: meter downloads versus self-report.

    Science.gov (United States)

    Guilfoyle, Shanna M; Crimmins, Nancy A; Hood, Korey K

    2011-09-01

    Reported frequencies of blood glucose monitoring (BGM) by both adolescents and their caregivers serve as adherence proxies when meter downloads are not available. Yet, correlates of reported BGM frequencies and their predictive utility are understudied. To identify sociodemographic, psychological, and disease-specific correlates of reported BGM frequencies in adolescents with type 1 diabetes and to explore the predictive utility of BGM indices on glycemic control. Study participants included caregivers and adolescents with type 1 diabetes (N=143, 13-18 yr) receiving diabetes treatment at a tertiary care setting. At the initial visit, adolescents and caregivers reported on daily BGM frequencies. A sub-sample provided meter downloads. Adolescents also completed a depression inventory. Three months later, adolescents provided blood sampling for A1c assessment. Multivariate general linear modeling identified that older adolescent age and more depressive symptoms were associated with reports of less frequent BGM. Two stepwise multivariate regression models examined the predictive utility of BGM indices (i.e., adolescent-reported BGM, caregiver-reported BGM, meter download) on glycemic control. Caregiver-reported BGM frequency predicted glycemic control in the absence of meter download data (pmeter download data were the most robust predictor of glycemic control (pMeter downloads have the most robust association with glycemic control when contextual variables are considered. Caregiver-reported BGM frequencies can serve as reliable substitutes in the absence of meter download, but they may not be as reliable in adolescents with depressive symptoms. © 2011 John Wiley & Sons A/S.

  15. Prescribing of Electronic Activity Monitors in Cardiometabolic Diseases: Qualitative Interview-Based Study.

    Science.gov (United States)

    Bellicha, Alice; Macé, Sandrine; Oppert, Jean-Michel

    2017-09-23

    The prevalence of noncommunicable diseases, including those such as type 2 diabetes, obesity, dyslipidemia, and hypertension, so-called cardiometabolic diseases, is high and is increasing worldwide. Strong evidence supports the role of physical activity in management of these diseases. There is general consensus that mHealth technology, including electronic activity monitors, can potentially increase physical activity in patients, but their use in clinical settings remains limited. Practitioners' requirements when prescribing electronic activity monitors have been poorly described. The aims of this qualitative study were (1) to explore how specialist physicians prescribe electronic activity monitors to patients presenting with cardiometabolic conditions, and (2) to better understand their motivation for and barriers to prescribing such monitors. We conducted qualitative semistructured interviews in March to May 2016 with 11 senior physicians from a public university hospital in France with expertise in management of cardiometabolic diseases (type 1 and type 2 diabetes, obesity, hypertension, and dyslipidemia). Interviews lasted 45 to 60 minutes and were audiotaped, transcribed verbatim, and analyzed using directed content analysis. We report our findings following the Consolidated Criteria for Reporting Qualitative Research (COREQ) checklist. Most physicians we interviewed had never prescribed electronic activity monitors, whereas they frequently prescribed blood glucose or blood pressure self-monitoring devices. Reasons for nonprescription included lack of interest in the data collected, lack of evidence for data accuracy, concern about work overload possibly resulting from automatic data transfer, and risk of patients becoming addicted to data. Physicians expected future marketing of easy-to-use monitors that will accurately measure physical activity duration and intensity and provide understandable motivating feedback. Features of electronic activity monitors

  16. Breath acetone to monitor life style interventions in field conditions: an exploratory study.

    Science.gov (United States)

    Samudrala, Devasena; Lammers, Gerwen; Mandon, Julien; Blanchet, Lionel; Schreuder, Tim H A; Hopman, Maria T; Harren, Frans J M; Tappy, Luc; Cristescu, Simona M

    2014-04-01

    To assess whether breath acetone concentration can be used to monitor the effects of a prolonged physical activity on whole body lipolysis and hepatic ketogenesis in field conditions. Twenty-three non-diabetic, 11 type 1 diabetic, and 17 type 2 diabetic subjects provided breath and blood samples for this study. Samples were collected during the International Four Days Marches, in the Netherlands. For each participant, breath acetone concentration was measured using proton transfer reaction ion trap mass spectrometry, before and after a 30-50 km walk on four consecutive days. Blood non-esterified free fatty acid (NEFA), beta-hydroxybutyrate (BOHB), and glucose concentrations were measured after walking. Breath acetone concentration was significantly higher after than before walking, and was positively correlated with blood NEFA and BOHB concentrations. The effect of walking on breath acetone concentration was repeatedly observed on all four consecutive days. Breath acetone concentrations were higher in type 1 diabetic subjects and lower in type 2 diabetic subjects than in control subjects. Breath acetone can be used to monitor hepatic ketogenesis during walking under field conditions. It may, therefore, provide real-time information on fat burning, which may be of use for monitoring the lifestyle interventions. Copyright © 2014 The Obesity Society.

  17. Large-scale indicators for monitoring forest diversity of the main forest types in Calabria (Italy

    Directory of Open Access Journals (Sweden)

    Infusino M

    2017-02-01

    Full Text Available Recently, the Society’s perception of forest resources has gone through significant changes. Forest ecosystems play a multifunctional role and host an important portion of the whole biodiversity, particularly in the Mediterranean area. Remote sensing technologies provide a unique way to obtain spatially extensive information on forest ecosystems, but relatively few studies used such information to evaluate forest habitat and biotic diversity. In this paper we evaluate the effectiveness of remote sensing to predict forest diversity by linking remotely sensed information with diversity metrics obtained from ground measurements of butterfly diversity. The field work was carried out in Calabria in four different forest types (beech, chestnut, black pine and silver fir forests. The sampling of Lepidoptera was carried out by LED light traps. We positioned 9 traps per forest type, for a total of 36 sites chosen to sample the different stages of forest succession in each forest type. Samples were carried out once a month from May to November 2015. Data from in situ butterfly measurements were compared with above ground forest biomass estimated from airborne LiDAR with NDVI estimated from Landsat 8. Results indicated that the Geometridae/Noctuideae ratio of lepidopteran communities was significantly correlated with the tree biomass, its distribution among tree size classes and the NDVI. The Geometridae/Noctuidae ratio, therefore, represents an index easy to calculate, which can be employed to integrate data acquired from remote sensing in order to obtain continuous spatial estimates of forest naturalness.

  18. Safety regulations regarding to accident monitoring and accident sampling at Russian NPPs with VVER type reactors

    International Nuclear Information System (INIS)

    Sharafutdinov, Rachet; Lankin, Michail; Kharitonova, Nataliya

    2014-01-01

    The paper describes a tendency by development of regulatory document requirements related to accident monitoring and accident sampling at Russia's NPPs. Lessons learned from the Fukushima Daiichi accident pointed at the importance and necessary to carry out an additional safety check at Russia's nuclear power plants in the preparedness for management of severe accidents at NPPs. Planned measures for improvement of severe accidents management include development and implementation of the accident instrumentation systems, providing, monitoring, management and storage of information in a severe accident conditions. The draft of Safety Guidelines <monitoring system of nuclear power plants with VVER reactors' prepared by Scientific and Engineering Centre for Nuclear and Radiation Safety (SEC NRS) established the main criteria for accident monitoring instrumentation that can monitor relevant plant parameters in the reactor and inside containment during and after a severe accident in nuclear power plants. Development of these safety guidelines is in line with the recommendations of IAEA Action Plan on Nuclear Safety in response to the Fukushima Daiichi event and recommendations of the IAEA Nuclear Energy series Report <Monitoring Systems for Nuclear Power Plants' (Draft V 2.7). The paper presents the principles, which are used as the basis for selection of plant parameters for accident monitoring and for establishing of accident monitoring instrumentation. The recommendations to the accident sampling system capable to obtain the representative reactor coolant and containment air and fluid samples that support accurate analytical results for the parameters of interest are considered. The radiological and chemistry parameters to be monitored for primary coolant and sump and for containment air are specified. (author)

  19. Monitoring post-fire recovery of shrublands in Mediterranean-type ecosystems using MODIS and TM/ETM+ data

    Science.gov (United States)

    Hope, Allen; Albers, Noah; Bart, Ryan

    2010-05-01

    Wildland fires in Mediterranean-Type Ecosystems (MTEs) are episodic events that dramatically alter land-cover conditions. Monitoring post-fire vegetation recovery is important for land management applications such as the scheduling of prescribed burns, post-fire resource management and soil erosion control. Full recovery of MTE shrublands may take many years and have a prolonged effect on water, energy and carbon fluxes in these ecosystems. Comparative studies of fynbos ecosystems in the Cape Floristic Region of South Africa (Western Cape Region) and chaparral ecosystems of California have demonstrated that there is a considerable degree of convergence in some aspects of post-fire vegetation regeneration and marked differences in other aspects. Since these MTEs have contrasting rainfall and soil nutrient conditions, an obvious question arises as to the similarity or dissimilarity in remotely sensed post-fire recovery pathways of vegetation stands in these two regions and the extent to which fire severity and drought impact the rate of vegetation recovery. Post-fire recovery pathways of chaparral and fynbos vegetation stands were characterized using the normalized difference vegetation index (NDVI) based on TM/ETM+ and MODIS (250 m) data. Procedures based on stands of unburned vegetation (control) were implemented to normalize the NDVI for variations associated with inter-annual differences in rainfall. Only vegetation stands that had not burned for 20 years were examined in this study to eliminate potential effects of variable fire histories on the recovery pathways. Post-fire recovery patterns of vegetation in both regions and across different vegetation types were found to be very similar. Post-fire stand age was the primary control over vegetation recovery and the NDVI returned to pre-fire values within seven to 10 years of the fires. Droughts were shown to cause slight interruptions in recovery rates while fire severity had no discernable effect. Intra

  20. High-resolution stable isotope monitoring reveals differential vegetation-soil water feedbacks among plant functional types

    Science.gov (United States)

    Volkmann, T. H. M.; Haberer, K.; Troch, P. A. A.; Gessler, A.; Weiler, M.

    2016-12-01

    Understanding the linked dynamics of rain water recharge to soils and its utilization by plants is critical for predicting the impact of climate and land use changes on the productivity of ecosystems and the hydrologic cycle. While plants require vast quantities of water from the soil to sustain growth and function, they exert important direct and indirect controls on the movement of water through the rooted soil horizons, thereby potentially affecting their own resource availability. However, the specific ecohydrological belowground processes associated with different plant types and their rooting systems have been difficult to quantify with traditional methods. Here, we report on the use of techniques for monitoring stable isotopes in soil and plant water pools that allow us to track water infiltration and root uptake dynamics non-destructively and in high resolution. The techniques were applied in controlled rain pulse experiments with distinct plant types (grass, deciduous trees, grapevine) that we let develop on an initially uniform soil for two years. Our results show that plant species and types differed widely in their plasticity and pattern of root uptake under variable water availability. Thereby, and through notably co-acting indirect effects related to differential root system traits and co-evolution of soil properties, the different plants induced contrasting hydrological dynamics in the soil they had inhabited for only a short period of time. Taken together, our data suggest that the studied soil-vegetation systems evolved a positive infiltration-uptake feedback in which hydrological flow pathways underlying different species diverged in a way that complemented their specific water utilization strategy. Such a feedback could present an indirect competitive mechanism by which plants improve their own water supply and modulate hydrological cycling at the land surface. The ability to directly measure this feedback using in situ isotope methodology

  1. Selection, application and monitoring of Lactobacillus paracasei strains as adjunct cultures in the production of Gouda-type cheeses.

    Science.gov (United States)

    Van Hoorde, Koenraad; Van Leuven, Isabelle; Dirinck, Patrick; Heyndrickx, Marc; Coudijzer, Kathleen; Vandamme, Peter; Huys, Geert

    2010-12-15

    Raw milk cheeses have more intense flavours than cheeses made from pasteurized milk and harbour strains with potential adjunct properties. Two Lactobacillus paracasei strains, R-40926 and R-40937, were selected as potential adjunct cultures from a total of 734 isolates from good quality artisan raw milk Gouda-type cheeses on the basis of their prevalence in different cheese types and/or over several production batches, safety and technological parameters. Conventional culturing, isolation and identification and a combined PCR-DGGE approach using total cheese DNA extracts and DNA extracts obtained from culturable fractions were employed to monitor viability of the introduced adjuncts and their effect on the cheese microbiota. The control cheese made without adjuncts was dominated by members of the starter, i.e. Lactococcus lactis and Leuconostoc pseudomesenteroides. In the cheeses containing either R-40926 or R-40937, the respective adjuncts increased in number as ripening progressed indicating that both strains are well adapted to the cheese environment and can survive in a competitive environment in the presence of a commercial starter culture. Principal component analysis of cheese volatiles determined by steam distillation-extraction and gas chromatography-mass spectrometry could differentiate cheeses made with different concentrations of adjunct R-40926 from the control cheese, and these differences could be correlated to the proteolytic and lipolytic properties of this strain. Collectively, results from microbiological and metabolic analyses indicate that the screening procedure followed throughout this study was successful in delivering potential adjunct candidates to enrich or extend the flavour palette of artisan Gouda-type cheeses under more controlled conditions. Copyright © 2010 Elsevier B.V. All rights reserved.

  2. Relationship between type of brain injury with Bispectral Index monitoring in intubated ICU trauma patients

    Directory of Open Access Journals (Sweden)

    Omid Moradi Moghaddam

    2015-05-01

    Conclusion: Different kinds of acute traumatic cranial lesions with different prognosis may have different values in BIS monitoring. Presence or absence of frontal lobe injury, had no statistically significant correlations with BIS values.

  3. On Algebraic Study of Type-2 Fuzzy Finite State Automata

    Directory of Open Access Journals (Sweden)

    Anupam K. Singh

    2017-08-01

    Full Text Available Theories of fuzzy sets and type-2 fuzzy sets are powerful mathematical tools for modeling various types of uncertainty. In this paper we introduce the concept of type-2 fuzzy finite state automata and discuss the algebraic study of type-2 fuzzy finite state automata, i.e., to introduce the concept of homomorphisms between two type-2 fuzzy finite state automata, to associate a type-2 fuzzy transformation semigroup with a type-2 fuzzy finite state automata. Finally, we discuss several product of type-2 fuzzy finite state automata and shown that these product is a categorical product.

  4. Three novel obese indicators perform better in monitoring management of metabolic syndrome in type 2 diabetes.

    Science.gov (United States)

    Ma, Chun-Ming; Lu, Na; Wang, Rui; Liu, Xiao-Li; Lu, Qiang; Yin, Fu-Zai

    2017-08-29

    The present study evaluated the performance of three novel obese indicators, visceral adiposity index (VAI), lipid accumulation product (LAP) and waist circumference-triglyceride index (WTI), for identifying metabolic syndrome(MetS) in type 2 diabetes. A cross-sectional study was conducted on 711 type 2 diabetes in Qinhuangdao. The MetS was defined as the definition of Chinese Diabetes Society. Receiver operating characteristic curve analyses were performed to assess the accuracy of three obese indicators as diagnostic tests for MetS. The prevalence of MetS was 71.3%. In men, among all three obese indicators, the LAP had the highest area under curve (AUC) value (AUC = 0.894), followed by VAI (AUC = 0.860) and WTI (AUC = 0.855). In women, among all three obese indicators, the LAP had the highest AUC value (AUC = 0.906), followed by WTI (AUC = 0.887) and VAI (AUC = 0.881). However. there was no significant difference between the three obese indicators(P > 0.05). Three obese indicators were effective indicators for the screening of MetS, LAP and WTI are more simple.

  5. The Dams and Monitoring Systems and Case Study: Ataturk and Karakaya Dams

    Science.gov (United States)

    Kalkan, Y.; Bilgi, S.; Gülnerman, A. G.

    2017-12-01

    type in Turkey. In addition, brief information is given about these dams and the methods of geodetic and non-geodetic monitoring measurements applied by various disciplines. The last part of the study focuses on the inference of the geodetic monitoring methods, which depend on a seven years of geodetic monitoring.

  6. The FOBIMO (FOraminiferal BIo-MOnitoring) initiative—Towards a standardised protocol for soft-bottom benthic foraminiferal monitoring studies

    Science.gov (United States)

    Schoenfeld, Joachim; Alve, Elisabeth; Geslin, Emmanuelle; Jorissen, Frans; Korsun, Sergei; Spezzaferri, Silva; Abramovich, Sigal; Almogi-Labin, Ahuva; Armynot du Chatelet, Eric; Barras, Christine; Bergamin, Luisa; Bicchi, Erica; Bouchet, Vincent; Cearreta, Alejandro; Di Bella, Letizia; Dijkstra, Noortje; Trevisan Disaro, Sibelle; Ferraro, Luciana; Frontalini, Fabrizio; Gennari, Giordana; Golikova, Elena; Haynert, Kristin; Hess, Silvia; Husum, Katrine; Martins, Virginia; McGann, Mary; Oron, Shai; Romano, Elena; Mello Sousa, Silvia; Tsujimoto, Akira

    2012-01-01

    The European Community Marine Strategy Framework Directive (MSFD) was established to provide guidelines for monitoring the quality of marine ecosystems. Monitoring the status of marine environments is traditionally based on macrofauna surveys, for which standardised methods have been established. Benthic foraminifera are also good indicators of environmental status because of their fast turnover rates, high degree of specialisation, and the preservation of dead assemblages in the fossil record. In spite of the growing interest in foraminiferal bio-monitoring during the last decades, no standardised methodology has been proposed until today. The aim of the FOraminiferal BIo-MOnitoring (FOBIMO) expert workshop, held in June 2011 at Fribourg, Switzerland, which assembled 37 scientists from 24 research groups and 13 countries, was to develop a suite of standard methods. This paper presents the main outcome of the workshop, a list of motivated recommendations with respect to sampling devices, sample storage, treatment, faunal analysis and documentation. Our recommendations fulfil the criteria imposed both by scientific rigour and by the practical limitations of routine studies. Hence, our aim is to standardise methodologies used in bio-monitoring only and not to limit the use of different methods in pure scientific studies. Unless otherwise stated, all recommendations concern living (stained) benthic foraminiferal assemblages. We have chosen to propose two types of recommendations. Mandatory recommendations have to be followed if a study wants to qualify as sound and compatible to the norms. The most important of these recommendations are the interval from 0 to 1 cm below the sediment surface has to be sampled, and an interface corer or box corer that keeps the sediment surface intact is to be used for offshore surveys. A grab sampler must not be deployed in soft sediments. Three replicate samples are to be taken and analysed separately. Samples are to be washed on a

  7. Study on Reactor Performance of Online Power Monitoring in PUSPATI TRIGA Reactor (RTP)

    International Nuclear Information System (INIS)

    Zareen Khan Abdul Jalil Khan; Ridzuan Abdul Mutalib; Mohd Sabri Minhat

    2014-01-01

    The Reactor TRIGA PUSPATI (RTP) at Malaysia Nuclear Agency is a TRIGA Mark II type reactor and pool type cooled by natural circulation of light water. This paper describe on reactor performance of online power monitoring based on various parameter of reactor such as log power, linear power, period, Fuel and coolant temperature and reactivity parameter with using neutronic and other instrumentation system of reactor. Methodology of online power estimation and monitoring is to evaluate and analysis of reactor power which is important of reactor safety and control. Neutronic instrumentation system will use to estimate power measurement, differential of log and linear power and period during reactor operation .This study also focus on noise fluctuation from fission chamber during reactor operation .This work will present result of online power monitoring from RTP which indicated the safety parameter identification and initiate safety action on crossing the threshold set point trip. Conclude that optimization of online power monitoring will improved the reactor control and safety parameter of reactor during operation. (author)

  8. Home-made temperature monitoring system from four-channel K-type thermocouples via internet of thing technology platform

    Science.gov (United States)

    Detmod, Thitaporn; Özmen, Yiǧiter; Songkaitiwong, Kittiphot; Saenyot, Khanuengchat; Locharoenrat, Kitsakorn; Lekchaum, Sarai

    2018-06-01

    This paper is aimed to design and construct the home-made temperature monitoring system from four-channel K-type thermocouples in order to improve the temperature measurement based on standard evaluation measurements guidance. The temperature monitoring system was capable to record the temperature on SD card and to display the realtime temperature on Internet of Thing Technology platform. The temperature monitoring system was tested in terms of the temperature measurement accuracy and delay response time. It was found that a standard deviation was acceptable as compared to the Instrument Society of America. The response time of the microcontroller to SD card was 2 sec faster than that of the microcontroller to Thingspeak.

  9. A study of reactor monitoring method with neural network

    Energy Technology Data Exchange (ETDEWEB)

    Nabeshima, Kunihiko [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2001-03-01

    The purpose of this study is to investigate the methodology of Nuclear Power Plant (NPP) monitoring with neural networks, which create the plant models by the learning of the past normal operation patterns. The concept of this method is to detect the symptom of small anomalies by monitoring the deviations between the process signals measured from an actual plant and corresponding output signals from the neural network model, which might not be equal if the abnormal operational patterns are presented to the input of the neural network. Auto-associative network, which has same output as inputs, can detect an kind of anomaly condition by using normal operation data only. The monitoring tests of the feedforward neural network with adaptive learning were performed using the PWR plant simulator by which many kinds of anomaly conditions can be easily simulated. The adaptively trained feedforward network could follow the actual plant dynamics and the changes of plant condition, and then find most of the anomalies much earlier than the conventional alarm system during steady state and transient operations. Then the off-line and on-line test results during one year operation at the actual NPP (PWR) showed that the neural network could detect several small anomalies which the operators or the conventional alarm system didn't noticed. Furthermore, the sensitivity analysis suggests that the plant models by neural networks are appropriate. Finally, the simulation results show that the recurrent neural network with feedback connections could successfully model the slow behavior of the reactor dynamics without adaptive learning. Therefore, the recurrent neural network with adaptive learning will be the best choice for the actual reactor monitoring system. (author)

  10. Effectiveness of Continuous Glucose Monitoring for Managing Type-1 Diabetic Patients and Barrier to Its Use: A Quasi Interventional Trial

    Directory of Open Access Journals (Sweden)

    Hassan M. Al-Musa

    2018-04-01

    Full Text Available Background: Type-1 diabetes is one of the largest endocrine and metabolic health issues among children and young adults. Diabetes mellitus is associated with many long-term complications. Aim and Objectives: To compare outcomes in groups monitored either by real time continuous glucose monitoring or by Self Monitoring of Blood Glucose (SMBG; 3-4 blood glucose measurements per day. Also we studied barrier for the use of CMG. Material and Methods: It is a prospective quasi experimental controlled trial at diabetic center in Abha, KSA. Out of 307 patients registered, 60 T1DM patients agreed to participate; out of them 30 patients were enrolled in intervention cohort, they used CGM sensor continuously while 30 patients were in the control group they used SMBG. All were followed for 6 months; HbA1c was measured at 3 and 6 months. Barrier to use of sensor was evaluated with a questionnaire. Results: At baseline no significant difference was observed in the average HbA1c between the groups (10.57 % vs 10.73 %. HbA1c reduction compared to baseline levels in the intervention cohort was 2.15% and 2.36% at 3 and 6 months. In control group, HbA1c reduced to 1.07% and 1.22% at 3 and 6 months showing significant difference (p=0.002 and p=0.001 at 3 and 6 months. Younger patients age <20 years had significantly better reduction of HbA1c (2.28% vs 1.27%, p=0.015 and 2.47% vs 1.98%, p=0.004 at 3 and 6 months. The hypoglycemic events were statistically reduced in the intervention group (p<0.001 and also the ketoacidosis and hospital admissions (20.0% vs, 3.3%, p<0.001. Conclusion: We found that the use of CGM sensor was associated with significant HbA1c reductions and improved glycaemic control.

  11. Spectroscopic monitoring of bright A-F type candidate hybrid stars discovered by the Kepler mission

    Science.gov (United States)

    Lampens, Patricia; Frémat, Y.; Vermeylen, Lore; De Cat, Peter; Dumortier, Louis; Sódor, Ádám; Sharka, Marek; Bognár, Zsófia

    2018-04-01

    We report on a study of 250 optical spectra for 50 bright A/F-type candidate hybrid pulsating stars from the Kepler field. Most of the spectra have been collected with the high-resolution spectrograph HERMES attached to the Mercator telescope, La Palma. We determined the radial velocities (RVs), projected rotational velocities, fundamental atmospheric parameters and provide a classification based on the appearance of the cross-correlation profiles and the behaviour of the RVs with time in order to find true hybrid pulsators. Additionally, we also detected new spectroscopic binary and multiple systems in our sample and determined the fraction of spectroscopic systems. In order to be able to extend this investigation to the fainter A-F type candidate hybrid stars, various high-quality spectra collected with 3-4 m sized telescopes suitably equipped with a high-resolution spectrograph and furthermore located in the Northern hemisphere would be ideal. This programme could be done using the new instruments installed at the Devasthal Observatory.

  12. Blade-type X-ray beam position monitors for SPring-8 undulator beamlines

    CERN Document Server

    Aoyagi, H; Kitamura, H

    2001-01-01

    The X-ray beam position monitors had been designed and installed for SPring-8 insertion device beamlines. These monitors are being utilized for photon beam diagnostics. The beam from the standard undulator in SPring-8 has the total power of 11 kW and the power density of 470 kW/mrad sup 2 , typically. Each monitor has four CVD diamond blades coated with metal for detector heads. We have already introduced three styles of monitors to match various insertion devices in SPring-8. A standard style, or a fixed-blade style, is used mainly for a standard in-vacuum undulator beamlines. A horizontal-blade-drive style and a four-blade-drive style are used for beamlines of a wiggler and a twin helical undulator that have wide power distributions, and for figure-8 undulators that have asymmetric power distributions, respectively. This report describes the design and the structure of these monitors and the beam-tests for the photon beam diagnostics in detail.

  13. [The Key Technology Study on Cloud Computing Platform for ECG Monitoring Based on Regional Internet of Things].

    Science.gov (United States)

    Yang, Shu; Qiu, Yuyan; Shi, Bo

    2016-09-01

    This paper explores the methods of building the internet of things of a regional ECG monitoring, focused on the implementation of ECG monitoring center based on cloud computing platform. It analyzes implementation principles of automatic identifi cation in the types of arrhythmia. It also studies the system architecture and key techniques of cloud computing platform, including server load balancing technology, reliable storage of massive smalfi les and the implications of quick search function.

  14. Type GQS-1 high pressure steam manifold water level monitoring system

    International Nuclear Information System (INIS)

    Li Nianzu; Li Beicheng; Jia Shengming

    1993-10-01

    The GQS-1 high pressure steam manifold water level monitoring system is an advanced nuclear gauge that is suitable for on-line detecting and monitor in high pressure steam manifold water level. The physical variable of water level is transformed into electrical pulses by the nuclear sensor. A computer is equipped for data acquisition, analysis and processing and the results are displayed on a 14 inch color monitor. In addition, a 4 ∼ 20 mA output current is used for the recording and regulation of water level. The main application of this gauge is for on-line measurement of high pressure steam manifold water level in fossil-fired power plant and other industries

  15. Understanding self-monitoring of blood glucose among individuals with type 1 and type 2 diabetes: an information-motivation-behavioral skills analysis.

    Science.gov (United States)

    Fisher, William A; Kohut, Taylor; Schachner, Holly; Stenger, Patricia

    2011-01-01

    To evaluate self-monitoring of blood glucose (SMBG) information deficits, motivational obstacles, and behavioral skills limitations in individuals with type 1 and type 2 diabetes, and to assess the relationship of these deficits with SMBG frequency. Individuals with type 1 (n = 208; 103 male, 105 female) and type 2 (n = 218; 107 male, 111 female) diabetes participated in an online survey assessing SMBG information, motivation, behavioral skills, and behavior. A substantial proportion of participants scored as SMBG uninformed, unmotivated, and unskilled on specific assessment items. SMBG information, motivation, and behavioral skills deficits were significantly correlated with SMBG frequency, such that individuals with type 1 or type 2 diabetes, who were less informed, less motivated, and less behaviorally skilled, reported lower frequency of SMBG. Common and consequential SMBG information, motivation, and behavioral skills deficits were present, and patients with these gaps were less likely to test frequently. Clinical education focusing on relevant SMBG information, motivation to act, and behavioral skills for acting effectively may be a priority.

  16. Study on autonomous decentralized-cooperative function monitoring system

    International Nuclear Information System (INIS)

    Matsuoka, Takeshi; Numano, Masayoshi; Someya, Minoru; Fukuto, Junji; Mitomo, Nobuo; Miyazaki, Keiko; Matsukura, Hiroshi; Tanba, Yasuyuki

    1999-01-01

    In this study, a study further advanced on a base of results of study on artificial intelligence for nuclear power', one of nuclear basis crossover studies, conducted at five years planning from 1989 fiscal year was executed. Here was conducted on study on a system technology for supplying cooperation, judgement process, judgement results, and so forth between decentralized artificial intelligent elements (agents) to operation managers (supervisors) by focussing a system for monitoring if autonomous decentralized system containing plant operation and robot group action functioned appropriately. In 1997 fiscal year, by mainly conducting development for displaying working state of robot group, some investigations on integrated management of each function already development and maintained were executed. Furthermore, some periodical meetings on realization of its integration with operation control system and maintenance system with other research institutes were conducted. (G.K.)

  17. A Practical Review of Studies on Operator's Supervisory Monitoring Behavior

    International Nuclear Information System (INIS)

    Ha, Jun Su; Seong, Poong Hyun

    2009-01-01

    Correct situation awareness (SA) has been considered a crucial key to improving performance and reducing error in NPPs. There are a lot of information sources that should be monitored in NPPs, but operators have only limited capacity of attention and memory. Operators in NPPs selectively attend to important information sources to effectively develop SA when an abnormal or accidental situation occurs. Selective attention to important information sources is continued while maintaining SA as well. In this work, various models of operator's visual sampling behavior are reviewed for the use in human factors studies in NPPs

  18. The Effect of Monitoring: How Data Collection Type and Frequency Boosts Participation and the Adoption of Best Practices in a Coffee Agronomy Training Program in Rwanda.

    Science.gov (United States)

    Gathani, Sachin; Gomez, Maria Paula; Sabates, Ricardo; Stoelinga, Dimitri

    2015-12-01

    The impact of surveying on individuals' behavior and decision making has been widely studied in academic literature on market research but not so much the impact of monitoring on economic development interventions. To estimate whether different monitoring strategies lead to improvement in participation levels and adoption of best practices for coffee production for farmer who participated in TechnoServe Agronomy Training Program in Rwanda. Farmers were identified randomly for monitoring purposes to belong to two different groups and then selected depending on the additional criterion of having productive coffee trees. We estimate treatment-on-the-treated and intention-to-treat effects on training attendance rates and farmers best-practice adoptions using difference-in-differences estimation techniques. Farmers were randomly identified to a high or low monitoring with different type and frequency of data collection and selected if they had productive coffee trees as part of the monitoring strategy. Attendance to training sessions by all farmers in the program and best-practice adoption data for improving coffee yield. We find that monitoring led to surprisingly large increases in farmer participation levels in the project and also improved best-practice adoption rates. We also find that higher frequency of data collection has long-lasting effects and are more pronounced for low-attendance farmers. Monitoring not only provides more data and a better understanding of project dynamics, which in turn can help improve design, but can also improve processes and outcomes, in particular for the least engaged. © The Author(s) 2016.

  19. Photoelectrochemical study of Si type P

    International Nuclear Information System (INIS)

    Ferreira, J.L.; Decker, F.

    1984-01-01

    Electrochemical reductions were studied at p-Si electrode under illumination and in the dark. Charge transfer mechanisms from the conduction and the valence band to different redox ions in solution were distinguished. Photoelectrochemical solar energy conversion has been studied as a particular case. (C.L.B.) [pt

  20. Study on loss detection algorithms for tank monitoring data using multivariate statistical analysis

    International Nuclear Information System (INIS)

    Suzuki, Mitsutoshi; Burr, Tom

    2009-01-01

    Evaluation of solution monitoring data to support material balance evaluation was proposed about a decade ago because of concerns regarding the large throughput planned at Rokkasho Reprocessing Plant (RRP). A numerical study using the simulation code (FACSIM) was done and significant increases in the detection probabilities (DP) for certain types of losses were shown. To be accepted internationally, it is very important to verify such claims using real solution monitoring data. However, a demonstrative study with real tank data has not been carried out due to the confidentiality of the tank data. This paper describes an experimental study that has been started using actual data from the Solution Measurement and Monitoring System (SMMS) in the Tokai Reprocessing Plant (TRP) and the Savannah River Site (SRS). Multivariate statistical methods, such as a vector cumulative sum and a multi-scale statistical analysis, have been applied to the real tank data that have superimposed simulated loss. Although quantitative conclusions have not been derived for the moment due to the difficulty of baseline evaluation, the multivariate statistical methods remain promising for abrupt and some types of protracted loss detection. (author)

  1. Validating visual disturbance types and classes used for forest soil monitoring protocols

    Science.gov (United States)

    D. S. Page-Dumroese; A. M. Abbott; M. P. Curran; M. F. Jurgensen

    2012-01-01

    We describe several methods for validating visual soil disturbance classes used during forest soil monitoring after specific management operations. Site-specific vegetative, soil, and hydrologic responses to soil disturbance are needed to identify sensitive and resilient soil properties and processes; therefore, validation of ecosystem responses can provide information...

  2. Medication adherence in type 2 diabetes patients: study of patients ...

    African Journals Online (AJOL)

    Medication adherence in type 2 diabetes patients: study of patients in ... impact of medication adherence on the clinical outcomes of type 2 diabetes patients at ... the review of case notes of one-hundred and fifty two randomly selected patients.

  3. Optimization of mass of plastic scintillator film for flow-cell based tritium monitoring: a Monte Carlo study

    International Nuclear Information System (INIS)

    Roy, Arup Singha; Palani Selvam, T.; Raman, Anand; Raja, V.; Chaudhury, Probal

    2014-01-01

    Over the years, various types of tritium-in-air monitors have been designed and developed based on different principles. Ionization chamber, proportional counter and scintillation detector systems are few among them. A plastic scintillator based, flow-cell type online tritium-in-air monitoring system was developed for online monitoring of tritium in air. The value of the scintillator mass inside the cell-volume, which maximizes the response of the detector system, should be obtained to get maximum efficiency. The present study is aimed to optimize the amount of mass of the plastic scintillator film for the flow-cell based tritium monitoring instrument so that maximum efficiency is achieved. The Monte Carlo based EGSnrc code system has been used for this purpose

  4. Monitoring the Various Types of Clostridium botulinumin in Four Kinds of Food Stuffs Using Multiplex PCR

    Directory of Open Access Journals (Sweden)

    Mohammad Vahid Sadeghi Sarvestani

    2014-03-01

    Full Text Available Background &Objective: Food poisoning (FP caused by C. botulinum is the most serious feature of FP inpeople consuming the contaminated foodstuffs (Canned meat, vegetarian foods, dairy products and seafood products. Botulism is basically detected by the identification of live bacteria and/or its toxins. Among various types of microorganisms (i.e. A, B, C1, C2, D, E, F, serotypes A, B, E and F are considered as the main human pathogens. The present study was aimed at investigating the possible roles of various foodstuffs to induce the food intoxication and also to compare the culture and molecular assays for identifying the microorganism.Materials &Methods: Three Lab techniques including biochemical, culture (enriched in TPGY and cooked meat medium and MPCR were used to detect C. botulinum in the samples. As the molecular based techniques have recently employed for the rapid and reliable identification of the bacteria and its toxins, the PCR assay, using three pairs of primers were designed and optimized to identify A, B and E strains in the contaminated specimens. The PCR was able to amplify 782, 205 and 389 bp genes specified for A, B and E types of the bacteria, respectively. Results: Total number of 290 specimens including fish, honey,"kashk"and"Dough" were tested, in which 5%, 4%, 2.5% and 1.25%, were found positive, respectively. Using selective culture of the specimens on the enriched samples, it was shown that just four samples were found positive.Conclusion: As a final conclusion, the molecular based techniques are recommended as a reliable tool to detect C. botulinum and, its toxins and spores in foodstuffs. Moreover, it is strongly advised to use it in food microbial Lab and also the epidemiological surveys.

  5. Performance and type testing of selected dosimeters used for individual monitoring

    International Nuclear Information System (INIS)

    Almhena, E. H. Y.

    2010-07-01

    This study describes calibration and performance testing carried out for a set of 14 electronic personal dosimeters (EPDs) and thermoluminescence dosimeters (TLDs ) at the Secondary Standard Dosimetry Laboratory of Sudan. Also the conversion coefficients from air kerma have been determined. Dosimeters tested are belonging to three manufactures representing most commonly used types in Sudan. Calibrations were carried out at three X-ray qualities: 80, 120 and 150 kV, ISO 'narrow' spectra and for ''1''3''7Cs, '' 60 Co gamma rays. The experiments were carried out using ICRU Slab phantom with dimension 30x30x15 cm. Secondary standard ionization chamber was used to measure the personal dose equivalent, Hp(10) as standard dosimetric quantity of interest. parameters tested include: The variation of response with radiation energy and angle of incident in addition to dose rate dependence. The angular dependence factors have been experimentally determined for the same qualities and for different angles (0, ±20, ±40, ±60u) + were performed in accordance to the relevant international standards. Excellent energy, angular and dose rate response was demonstrated for 662 137 Cs, 1250 60 Co beam and (118, 100,65 keV) x-ray beam qualities exception the EPD at PM1203M are slightly larger but still with the acceptable. The response of electronic dosimeters were found to in limits of acceptable performance. For the mean response of all energies is range of EPDs Type RADOS 60, Greatz ED 150, Polimaster PM1203M, TLD were (0.75 ±0.08- 1.13±0.13), (0.83±0.29 -1.06±0.07), (1.08±0.14-1.27±0.09), (0.99±0.05 - 1.14±0.13) respectively. The majority of the dosimeters tested showed good energy and angular response. (Author)

  6. Structured self monitoring of blood glucose in Iranian people with type 2 diabetes; A cost consequence analysis

    Directory of Open Access Journals (Sweden)

    Aghili Rokhsareh

    2012-09-01

    Full Text Available Abstract Background Self-Monitoring of Blood Glucose (SMBG is considered as a key factor in management of people with diabetes which is a growing and cost demanding health problem. The purpose of this study was to investigate the effect of comprehensive patient management using structured SMBG on metabolic control as well as its cost consequence analysis. Methods Sixty subjects were recruited in an observational study for a period of 6 months. They were provided with the ACCU-CHEK 360° View tool to fill in the values of the 7-point blood glucose profiles in three consecutive days during the study on a monthly basis. Changes in metabolic control were assessed by HbA1c and lipid profile measurement at the beginning and at the end of the study. In addition, cost consequence analysis was done considering different level of health care professionals with or without insurance coverage. The Average Cost Effectiveness Ratio (ACER as well as Cost saving analysis were calculated and compared. Results The analysis showed significant reduction in HbA1c during the 6-month period in all subjects (P = 0.000. Furthermore, a positive effect was observed on lipid profile. The cost of endocrinologist’s visit in private sector was estimated to be 265.76 USD while this figure was149.15 USD for general practitioner in public sector with insurance coverage. Total complications and mortality cost saving was 154.8 USD. The lowest ACER was calculated for intervention with general practitioner in public sector with insurance coverage. Conclusion Structured SMBG results in significant improvement of glycemic status. Moreover, it is more cost saving in public sector with insurance coverage. It seems that general practitioner visits with insurance coverage is the most affordable option for people with type 2 diabetes.

  7. Factors affecting mobile diabetes monitoring adoption among physicians: questionnaire study and path model.

    Science.gov (United States)

    Okazaki, Shintaro; Castañeda, José Alberto; Sanz, Silvia; Henseler, Jörg

    2012-12-21

    Patients with type 1 and type 2 diabetes often find it difficult to control their blood glucose level on a daily basis because of distance or physical incapacity. With the increase in Internet-enabled smartphone use, this problem can be resolved by adopting a mobile diabetes monitoring system. Most existing studies have focused on patients' usability perceptions, whereas little attention has been paid to physicians' intentions to adopt this technology. The aim of the study was to evaluate the perceptions and user acceptance of mobile diabetes monitoring among Japanese physicians. A questionnaire survey of physicians was conducted in Japan. The structured questionnaire was prepared in a context of a mobile diabetes monitoring system that controls blood glucose, weight, physical activity, diet, insulin and medication, and blood pressure. Following a thorough description of mobile diabetes monitoring with a graphical image, questions were asked relating to system quality, information quality, service quality, health improvement, ubiquitous control, privacy and security concerns, perceived value, subjective norms, and intention to use mobile diabetes monitoring. The data were analyzed by partial least squares (PLS) path modeling. In total, 471 physicians participated from 47 prefectures across Japan, of whom 134 were specialized in internal and gastrointestinal medicine. Nine hypotheses were tested with both the total sample and the specialist subsample; results were similar for both samples in terms of statistical significance and the strength of path coefficients. We found that system quality, information quality, and service quality significantly affect overall quality. Overall quality determines the extent to which physicians perceive the value of mobile health monitoring. However, in contrast to our initial predictions, overall quality does not have a significant direct effect on the intention to use mobile diabetes monitoring. With regard to net benefits, both

  8. ITRAP - an international pilot study on border monitoring systems

    International Nuclear Information System (INIS)

    Beck, P.; Duftschmid, K.E.

    1999-01-01

    The paper describes the design and preliminary results of an extended pilot study of commercially available monitoring systems for the detection of nuclear and other radioactive materials at borders. The study consists of a laboratory test phase and field tests at the Austrian/Hungarian border and the Vienna airport, each for a duration of one year. The results will be used to derive realistic performance requirements for border control systems in view of optimized technical and economic conditions as well as to propose an 'investigation level'. The ITRAP study consists of three phases. In the first phase equipment currently available on the market is subjected to laboratory testing at the Austrian Research Centres Seibersdorf. The instrument categories include hand-held, portable, and fixed-installed equipment. The test criteria defined as minimum requirements have been established together with the manufacturers. The laboratory tests started in May 1998 and will last until end of this year. During the second phase, the field study, equipment passing the laboratory tests will be installed at a major Austrian-Hungarian border crossing (Nickelsdorf) for monitoring of cars, trucks and trains, as well as at the Vienna airport for pedestrians, luggage and cargo. In this phase the results gained from the lab tests about the 'fitness for use' will be verified in practice, in close co-operation with the law enforcement officers at the borders. Also training issues and questions of maintenance and support shall be evaluated. In the third phase, realistic specifications and performance requirements shall be derived with the help of international experts and selected specialists from the users and manufacturers. The results of the field study will focus not only on the technical aspects of monitoring equipment (e.g. detection threshold and rate of false alarms) but also on the operational (e.g. ease of use, reliability, training requirements, field support) and economic

  9. Flash glucose monitoring system may benefit children and adolescents with type 1 diabetes during fasting at Ramadan.

    Science.gov (United States)

    Al-Agha, Abdulmoein E; Kafi, Shahd E; Zain Aldeen, Abdullah M; Khadwardi, Raghdah H

    2017-04-01

    To assess the benefit of using the flash glucose monitoring system (FGMS) in children and adolescents with type 1 diabetes mellitus (T1DM) during Ramadan fasting. Methods: A prospective pilot study of 51 participants visited the pediatric diabetes clinic at King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia from between June until and July 2016. The FreeStyle® Libre™ FGMS (Abbott Diabetes Care, Alameda, CA, USA) was used. Hypoglycemia was defined as glucose values of less than 70 mg/dL, while hyperglycemia as glucose values of more than 150 mg/dL for all participants based on our institute's protocol. Results: Participants were able to fast for 67.0% of the total days eligible for fasting, whereas they did not fast on 33% of the days due to either hypoglycemia (15.4%) or non-diabetes-related reasons (17.6 %). None of the participants developed severe hypoglycemia. The mean number of hyperglycemic episodes during fasting hours was 1.29, per day, which was higher than that of hypoglycemic episodes (0.7). None of the participants developed diabetic ketoacidosis (DKA). Glycemic control with mean of estimated hemoglobin A1C reading during Ramadan (8.16 ± 1.64% [pre study]) to 8.2 ± 1.63% [post study] p=0.932. Conclusions: Children and adolescents with T1DM who use the FGMS could fast without the risk of life-threatening episodes of severe hypoglycemia (namely seizure, coma), or DKA during Ramadan. Adequate education and good glycemic control prior to Ramadan are important strategies in combination with the use of an FGMS to achieve better outcome.

  10. Flash glucose monitoring system may benefit children and adolescents with type 1 diabetes during fasting at Ramadan

    Directory of Open Access Journals (Sweden)

    Abdulmoein E. Al-Agha

    2017-04-01

    Full Text Available Objectives: To assess the benefit of using the flash glucose monitoring system (FGMS in children and adolescents with type 1 diabetes mellitus (T1DM during Ramadan fasting. Methods: A prospective pilot study of 51 participants visited the pediatric diabetes clinic at King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia from between June until and July 2016. The FreeStyle® Libre™ FGMS (Abbott Diabetes Care, Alameda, CA, USA was used. Hypoglycemia was defined as glucose values of less than 70 mg/dL, while hyperglycemia as glucose values of more than 150 mg/dL for all participants based on our institute’s protocol. Results: Participants were able to fast for 67.0% of the total days eligible for fasting, whereas they did not fast on 33% of the days due to either hypoglycemia (15.4% or non-diabetes-related reasons (17.6 %. None of the participants developed severe hypoglycemia. The mean number of hyperglycemic episodes during fasting hours was 1.29, per day, which was higher than that of hypoglycemic episodes (0.7. None of the participants developed diabetic ketoacidosis (DKA. Glycemic control with mean of estimated hemoglobin A1C reading during Ramadan (8.16 ± 1.64% [pre study] to 8.2 ± 1.63% [post study] p=0.932. Conclusions: Children and adolescents with T1DM who use the FGMS could fast without the risk of life-threatening episodes of severe hypoglycemia (namely seizure, coma, or DKA during Ramadan. Adequate education and good glycemic control prior to Ramadan are important strategies in combination with the use of an FGMS to achieve better outcome.

  11. A STUDY ON HEALTH MONITORING SYSTEM: RECENT ADVANCEMENTS

    Directory of Open Access Journals (Sweden)

    Atika Arshad

    2014-12-01

    Full Text Available ABSTRACT: A proliferating interest has been observed over the past years in the development of an accurate system for monitoring continuous human activities in the health care sectors, especially for the elderly. This paper conducts a survey of the various techniques and methods that are proposed to monitor the movements and activities of the elderly people. These techniques promise a useful and dependable detection system to give support and lessen the medical expenses of health care for the elderly. The detection approaches are divided into five main categories: wearable device based, wireless based, ambience device based, vision based and floor sensor / electric field sensors based. These techniques have focused on the pros and cons of the existing methods for recognizing the prospective scope of research in the domain of health monitoring systems. Apart from highlighting and analyzing the features of the existing techniques, perspectives on probable future studies have been detailed. ABSTRAK: Dewasa ini, pembangunan sistem yang tepat untuk memantau aktiviti berterusan terutamanya dalam sektor kesihatan warga tua mula mendapat tempat. Kaji selidik telah dijalankan dengan pelbagai teknik dan kaedah untuk meninjau pergerakan dan aktiviti golongan warga tua. Kaedah-kaedah ini memberikan sistem pengesanan yang berguna dan dipercayai untuk memberikan sokongan serta mengurangkan kos perubatan kesihatan bagi golongan tua. Pendekatan pengesanan dibahagikan kepada lima kategori utama; alatan yang dapat dipakai, alatan tanpa wayar, alatan berdasarkan persekitaran, alatan berasaskan penglihatan dan alatan berdasarkan pengesan pada lantai / medan elektrik.  Teknik-teknik ini memfokuskan kepada pro dan kontra kaedah yang sedia ada untuk mengenalpasti skop prospektif penyelidikan dalam domain sistem pengawasan kesihatan.  Selain daripada mengetengah dan menganalisa ciri-ciri teknik yang sedia ada, perspektif kajian akan datang juga diperincikan

  12. Continuous Glucose Monitoring vs Conventional Therapy for Glycemic Control in Adults With Type 1 Diabetes Treated With Multiple Daily Insulin Injections: The GOLD Randomized Clinical Trial.

    Science.gov (United States)

    Lind, Marcus; Polonsky, William; Hirsch, Irl B; Heise, Tim; Bolinder, Jan; Dahlqvist, Sofia; Schwarz, Erik; Ólafsdóttir, Arndís Finna; Frid, Anders; Wedel, Hans; Ahlén, Elsa; Nyström, Thomas; Hellman, Jarl

    2017-01-24

    The majority of individuals with type 1 diabetes do not meet recommended glycemic targets. To evaluate the effects of continuous glucose monitoring in adults with type 1 diabetes treated with multiple daily insulin injections. Open-label crossover randomized clinical trial conducted in 15 diabetes outpatient clinics in Sweden between February 24, 2014, and June 1, 2016 that included 161 individuals with type 1 diabetes and hemoglobin A1c (HbA1c) of at least 7.5% (58 mmol/mol) treated with multiple daily insulin injections. Participants were randomized to receive treatment using a continuous glucose monitoring system or conventional treatment for 26 weeks, separated by a washout period of 17 weeks. Difference in HbA1c between weeks 26 and 69 for the 2 treatments. Adverse events including severe hypoglycemia were also studied. Among 161 randomized participants, mean age was 43.7 years, 45.3% were women, and mean HbA1c was 8.6% (70 mmol/mol). A total of 142 participants had follow-up data in both treatment periods. Mean HbA1c was 7.92% (63 mmol/mol) during continuous glucose monitoring use and 8.35% (68 mmol/mol) during conventional treatment (mean difference, -0.43% [95% CI, -0.57% to -0.29%] or -4.7 [-6.3 to -3.1 mmol/mol]; P < .001). Of 19 secondary end points comprising psychosocial and various glycemic measures, 6 met the hierarchical testing criteria of statistical significance, favoring continuous glucose monitoring compared with conventional treatment. Five patients in the conventional treatment group and 1 patient in the continuous glucose monitoring group had severe hypoglycemia. During washout when patients used conventional therapy, 7 patients had severe hypoglycemia. Among patients with inadequately controlled type 1 diabetes treated with multiple daily insulin injections, the use of continuous glucose monitoring compared with conventional treatment for 26 weeks resulted in lower HbA1c. Further research is needed to assess clinical outcomes and longer

  13. Mood instability in bipolar disorder type I versus type II-continuous daily electronic self-monitoring of illness activity using smartphones

    DEFF Research Database (Denmark)

    Faurholt-Jepsen, Maria; Ritz, Christian; Frost, Mads

    2015-01-01

    BACKGROUND: A substantial proportion of patients with bipolar disorder remain symptomatic during inter-episode periods, and mood instability is associated with high risk of relapse and hospitalization. Few studies have investigated long-term daily illness activity and none has compared bipolar ty...... with bipolar disorder type I, but despite on-going treatment only for half of the time for patients with bipolar disorder type II. This emphasizes the need for improving treatment strategies for bipolar disorder type II....

  14. Lower Columbia River and Estuary Habitat Monitoring Study, 2011 - Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Borde, Amy B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kaufmann, Ronald M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Cullinan, Valerie I. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Zimmerman, Shon A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Thom, Ronald M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Wright, Cynthia L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2012-03-01

    The Ecosystem Monitoring Program is a collaborative effort between the Lower Columbia River Estuary Partnership (LCREP), University of Washington, Wetland Ecosystem Team (UW), US Geological Survey, Water Science Center (USGS), National Oceanic and Atmospheric Administration, National Marine Fisheries Service (NOAA-Fisheries, hereafter NOAA), and Pacific Northwest National Laboratory, Marine Sciences Laboratory (PNNL). The goal of the program is to conduct emergent wetland monitoring aimed at characterizing salmonid habitats in the lower Columbia River and estuary (LCRE) from the mouth of the estuary to Bonneville Dam (Figure 1). This is an ecosystem based monitoring program focused on evaluating status and trends in habitat and reducing uncertainties regarding these ecosystems to ultimately improve the survival of juvenile salmonids through the LCRE. This project comprehensively assesses habitat, fish, food web, and abiotic conditions in the lower river, focusing on shallow water and vegetated habitats used by juvenile salmonids for feeding, rearing and refugia. The information is intended to be used to guide management actions associated with species recovery, particularly that of threatened and endangered salmonids. PNNL’s role in this multi-year study is to monitor the habitat structure (e.g., vegetation, topography, channel morphology, and sediment type) as well as hydrologic patterns.

  15. Advanced hemodynamic monitoring in intensive care medicine : A German web-based survey study.

    Science.gov (United States)

    Saugel, B; Reese, P C; Wagner, J Y; Buerke, M; Huber, W; Kluge, S; Prondzinsky, R

    2018-04-01

    Advanced hemodynamic monitoring is recommended in patients with complex circulatory shock. To evaluate the current attitudes and beliefs among German intensivists, regarding advanced hemodynamic monitoring, the actual hemodynamic management in clinical practice, and the barriers to using it. Web-based survey among members of the German Society of Medical Intensive Care and Emergency Medicine. Of 284 respondents, 249 (87%) agreed that further hemodynamic assessment is needed to determine the type of circulatory shock if no clear clinical diagnosis can be made. In all, 281 (99%) agreed that echocardiography is helpful for this purpose (transpulmonary thermodilution: 225 [79%]; pulmonary artery catheterization: 126 [45%]). More than 70% of respondents agreed that blood flow variables (cardiac output, stroke volume) should be measured in patients with hemodynamic instability. The parameters most respondents agreed should be assessed in a patient with hemodynamic instability were mean arterial pressure, cardiac output, and serum lactate. Echocardiography is available in 99% of ICUs (transpulmonary thermodilution: 91%; pulmonary artery catheter: 63%). The respondents stated that, in clinical practice, invasive arterial pressure measurements and serum lactate measurements are performed in more than 90% of patients with hemodynamic instability (cardiac output monitoring in about 50%; transpulmonary thermodilution in about 40%). The respondents did not feel strong barriers to the use of advanced hemodynamic monitoring in clinical practice. This survey study shows that German intensivists deem advanced hemodynamic assessment necessary for the differential diagnosis of circulatory shock and to guide therapy with fluids, vasopressors, and inotropes in ICU patients.

  16. A Real-Time Data Monitoring and Accumulation System for Dynamic Studies with Radionuclides

    Energy Technology Data Exchange (ETDEWEB)

    Ammann, W.; Doll, J.; Lorenz, W. J.; Ostertag, H.; Adam, W. E.; Scheer, K. E. [German Cancer Research Centre, Institute of Nuclear Medicine, Heidelberg, Federal Republic of Germany (Germany)

    1971-02-15

    A multipurpose digital data monitoring and accumulation system is described. The central unit of the system is a PDP-8 computer with a 12K memory. The system contains furthermore a multipurpose digital input/output register for low data rates, a fourfold and a twofold ADC connected to the high-speed multiplexor unit of the PDP-8 and a digital timet. Data from various process peripheries are recorded on a nine-track IBM compatible Ampex tape recorder. When two co-ordinates are recorded the system is used in the ''add-one-to-storage'' mode. In the case of more than two co-ordinates the data are stored in the sequential mode, event by event. A dialogue real-time monitor program in assembler language was developed to control the process peripheries. The 4K-Fortran operating system was modified in such a way that monitor subroutines were called into the Fortran program without loss of the real-time properties of the monitor system during a Fortran run. The use of the system for lung function studies with an Anger-type scintillation camera and {sup 133}Xe is discussed as an example of the application of the system. (author)

  17. Frequency and motives of blood glucose self-monitoring in type 1 diabetes

    DEFF Research Database (Denmark)

    Hansen, M.V.; Pedersen-Bjergaard, U.; Heller, S.R.

    2009-01-01

    AIMS: Recommendations for self-monitoring of blood glucose (SMBG) from the DCCT have not been implemented with the same rigour as recommendations for intensifying insulin therapy. We assessed the frequency of and motives for SMBG and compared SMBG behaviour with clinical, behavioural......% of the patients and less than weekly by 24%. Sixty-seven percent reported to perform routine testing, while the remaining 33% only tested when hypo- or hyperglycaemia was suspected. Age, gender, and level of diabetes-related concern were associated with test pattern. Reported frequencies of mild and severe...

  18. Study on the forest vegetation restoration monitoring using HJ-1A hyperspectral data

    International Nuclear Information System (INIS)

    Chuan, Zhang; Fawang, Ye; Hongcheng, Liu; Haixia, He

    2014-01-01

    In this paper, Xunke County was studied using HJ-1A hyperspectral data for monitoring vegetation restoration after forest fires. The pre-processing procedure including data format conversion, image mosaicing and atmospheric correction. Support vector machine classification was used to perform surface feature identification based on the extracted spectral end-members. On that basis, the image area was divided into seven categories and statistical analysis of classification types was performed. The results showed that HJ-1A hyperspectral data had great potential in fine classification of surface features and the accuracy of classification was 91.8%. The mild and severe fire-affected area extraction provided useful reference for disaster recovery monitoring. Furthermore, the distinction between coniferous forest and broadleaved forest can offer useful information for forest fire prevention and early warning to some extent

  19. Personality at Work: A Study of Type A-B

    Directory of Open Access Journals (Sweden)

    Amber Raza

    2007-10-01

    Full Text Available The objective of this study was to measure the impact of stressors on personality types in Call Centers. Based on literature survey five potential workplace stressors were identified, namely (1 Task Demands, (2 Role Demands, (3 Interpersonal Demands, (4 Organizational Structure and (5 Organizational Leadership. Based on the literature survey, a relationship model was developed that was inclusive of the above stressors, and three personality types, which were Type A, Type AB and Type B.The sample size for the study was 100. The subjects were supervisors and agents drawn non-randomly from various Call Centers of Karachi. All the subjects completed a questionnaire comprised of 27 questions based on occupational stress index (Srivasta and Singh 1981 and AB Personality Continuum (National Institute of Safety and Health 1975. The three personality types A, B & AB all go through stress, however it is the Type A, which thrives on stress. The sources of stress measured in the study were Task Demand, Role Demand, Interpersonal Demands, Organizational Structure and Organizational Leadership.The stressor that most contributed to the Personality type A’s stress in the study was Interpersonal Demand (0.38, which is justified by the literature review as Personality type A are not team players and prefer to work alone.Whereas Personality type B was stressed because of Role Demand (0.38 which is also proved by the literature review as personality type B are laid back and do not take there roles seriously. Hence it can be concluded that it type A tends to cope well with stress as compared to type AB and type B. The performance of the respondents can be made better if the supervisors are aware of the personality types and thereby motivate them according.

  20. Self-Monitoring Using Continuous Glucose Monitors with Real-Time Feedback Improves Exercise Adherence in Individuals with Impaired Blood Glucose: A Pilot Study.

    Science.gov (United States)

    Bailey, Kaitlyn J; Little, Jonathan P; Jung, Mary E

    2016-03-01

    Exercise helps individuals with prediabetes or type 2 diabetes (T2D) manage their blood glucose (BG); however, exercise adherence in this population is dismal. In this pilot study we tested the efficacy of a self-monitoring group-based intervention using continuous glucose monitors (CGMs) at increasing exercise adherence in individuals with impaired BG. Thirteen participants with prediabetes or T2D were randomized to an 8-week standard care exercise program (CON condition) (n = 7) or self-monitoring exercise intervention (SM condition) (n = 6). Participants in the SM condition were taught how to self-monitor their exercise and BG, to goal set, and to use CGM to observe how exercise influences BG. We hypothesized that compared with the CON condition, using a real-time CGM would facilitate self-monitoring behavior, resulting in increased exercise adherence. Repeated-measures analysis of variance revealed significant Condition × Time interactions for self-monitoring (P goal setting (P = 0.01), and self-efficacy to self-monitor (P = 0.01), such that the SM condition showed greater increases in these outcomes immediately after the program and at the 1-month follow-up compared with the CON condition. The SM condition had higher program attendance rates (P = 0.03), and a greater proportion of participants reregistered for additional exercise programs (P = 0.048) compared with the CON condition. Participants in both conditions experienced improvements in health-related quality of life, waist circumference, and fitness (P values exercise behavior in individuals living with prediabetes or T2D.

  1. Case studies of capacity building for biodiversity monitoring: Chapter 13

    Science.gov (United States)

    Schmeller, Dirk S.; Arvanitidis, Christos; Böhm, Monika; Brummitt, Neil; Chatzinikolaou, Eva; Costello, Mark J.; Ding, Hui; Gill, Michael J.; Haase, Peter; Juillard, Romain; García-Moreno, Jaime; Pettorelli, Nathalie; Peng, Cui; Riginos, Corinna; Schmiedel, Ute; Simaika, John P.; Waterman, Carly; Wu, Jun; Xu, Haigen; Belnap, Jayne; Walters, Michele; Scholes, Robert J.

    2017-01-01

    Monitoring the status and trends of species is critical to their conservation and management. However, the current state of biodiversity monitoring is insufficient to detect such for most species and habitats, other than in a few localised areas. One of the biggest obstacles to adequate monitoring is the lack of local capacity to carry out such programs. Thus, building the capacity to do such monitoring is imperative. We here highlight different biodiversity monitoring efforts to illustrate how capacity building efforts are being conducted at different geographic scales and under a range of resource, literacy, and training constraints. Accordingly, we include examples of monitoring efforts from within countries (Kenya, France, and China), within regions (Central America and the Arctic) and larger capacity building programs including EDGE (Evolutionarily Distinct and Globally Endangered) of Existence and the National Red List Alliance.

  2. The laboratory-type data input and processing subsystem of the country-wide environmental radiation monitoring system in Hungary

    International Nuclear Information System (INIS)

    Kanyar, B.; Fulop, N.; Glavatszkih, N.; Nemeth, A.

    1996-01-01

    The countrywide radiation monitoring activity in Hungary is shared among the national networks as agriculture, environmental protection and public health ones. They are mostly involved in the environmental sampling and laboratory type determinations of the radioactive pollution, meanwhile the organisations mainly from the Army and Civil Defence are responsible to the early warning system. A moderately effective collaboration is established only around the Nuclear Power Plant Paks. Based on more than 10 years experience in collaboration around the NPP the Hungarian Atomic Energy Commission initiated some centralism in the countrywide monitoring activity as well. As the first step the National Research Institute for Radiobiology and Radiohygiene has been charged to establish an Information Center for laboratory-type data collection, processing, analysis and informing regularly the proper organizations on the results. The Information Centre is equipped with a computer type of SUN SPARCserver-20 and the laboratories are planned to be linked on line by PC stations. The main user programs for data collection, control and restricted processing are written in INGRES data manager software. The semiprocessed results can be transformed in a readable form for general statistical etc. packages

  3. Wireless online position monitoring of manual valve types for plant configuration management in nuclear power plants

    International Nuclear Information System (INIS)

    Agarwal, Vivek; Buttles, John W.; Beaty, Lawrence H.; Naser, Joseph; Hallbert, Bruce P.

    2016-01-01

    In the current competitive energy market, the nuclear industry is committed to lower the operations and maintenance cost; increase productivity and efficiency while maintaining safe and reliable operation. The present operating model of nuclear power plants is dependent on large technical staffs that put the nuclear industry at long-term economic disadvantage. Technology can play a key role in nuclear power plant configuration management in offsetting labor costs by automating manually performed plant activities. The technology being developed, tested, and demonstrated in this paper will enable the continued safe operation of today’s fleet of light water reactors by providing the technical means to monitor components in plants today that are only routinely monitored through manual activities. The wireless enabled valve position indicators that are the subject of this paper are able to provide a valid position indication available continuously, rather than only periodically. As a result, a real-time (online) availability of valve positions using an affordable technologies are vital to plant configuration when compared with long-term labor rates, and provide information that can be used for a variety of plant engineering, maintenance, and management applications.

  4. A glasses-type wearable device for monitoring the patterns of food intake and facial activity

    Science.gov (United States)

    Chung, Jungman; Chung, Jungmin; Oh, Wonjun; Yoo, Yongkyu; Lee, Won Gu; Bang, Hyunwoo

    2017-01-01

    Here we present a new method for automatic and objective monitoring of ingestive behaviors in comparison with other facial activities through load cells embedded in a pair of glasses, named GlasSense. Typically, activated by subtle contraction and relaxation of a temporalis muscle, there is a cyclic movement of the temporomandibular joint during mastication. However, such muscular signals are, in general, too weak to sense without amplification or an electromyographic analysis. To detect these oscillatory facial signals without any use of obtrusive device, we incorporated a load cell into each hinge which was used as a lever mechanism on both sides of the glasses. Thus, the signal measured at the load cells can detect the force amplified mechanically by the hinge. We demonstrated a proof-of-concept validation of the amplification by differentiating the force signals between the hinge and the temple. A pattern recognition was applied to extract statistical features and classify featured behavioral patterns, such as natural head movement, chewing, talking, and wink. The overall results showed that the average F1 score of the classification was about 94.0% and the accuracy above 89%. We believe this approach will be helpful for designing a non-intrusive and un-obtrusive eyewear-based ingestive behavior monitoring system.

  5. Idaho Steelhead Monitoring and Evaluation Studies : Annual Progress Report 2007.

    Energy Technology Data Exchange (ETDEWEB)

    Copeland, Timothy; Putnam, Scott

    2008-12-01

    The goal of Idaho Steelhead Monitoring and Evaluation Studies is to collect monitoring data to evaluate wild and natural steelhead populations in the Clearwater and Salmon river drainages. During 2007, intensive population data were collected in Fish Creek (Lochsa River tributary) and Rapid River (Little Salmon River tributary); extensive data were collected in other selected spawning tributaries. Weirs were operated in Fish Creek and Rapid River to estimate adult escapement and to collect samples for age determination and genetic analysis. Snorkel surveys were conducted in Fish Creek, Rapid River, and Boulder Creek (Little Salmon River tributary) to estimate parr density. Screw traps were operated in Fish Creek, Rapid River, Secesh River, and Big Creek to estimate juvenile emigrant abundance, to tag fish for survival estimation, and to collect samples for age determination and genetic analysis. The estimated wild adult steelhead escapement in Fish Creek was 81 fish and in Rapid River was 32 fish. We estimate that juvenile emigration was 24,127 fish from Fish Creek; 5,632 fish from Rapid River; and 43,674 fish from Big Creek. The Secesh trap was pulled for an extended period due to wildfires, so we did not estimate emigrant abundance for that location. In cooperation with Idaho Supplementation Studies, trap tenders PIT tagged 25,618 steelhead juveniles at 18 screw trap sites in the Clearwater and Salmon river drainages. To estimate age composition, 143 adult steelhead and 5,082 juvenile steelhead scale samples were collected. At the time of this report, 114 adult and 1,642 juvenile samples have been aged. Project personnel collected genetic samples from 122 adults and 839 juveniles. We sent 678 genetic samples to the IDFG Eagle Fish Genetics Laboratory for analysis. Water temperature was recorded at 37 locations in the Clearwater and Salmon river drainages.

  6. Comparison of image quality between mammography dedicated monitor and UHD 4K monitor, using standard mammographic phantom: A preliminary study

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Ji Young; Cha, Soon Joo; Hong, Sung Hwan; Kim, Su Young; Kim, Yong Hoon; Kim, You Sung; Kim, Jeong A [Dept. of Radiology, Inje Unveristy Ilsan Paik Hospital, Goyang (Korea, Republic of)

    2017-03-15

    Using standard mammographic phantom images, we compared the image quality obtained between a mammography dedicated 5 megapixel monitor (5M) and a UHD 4K (4K) monitor with digital imaging and communications in medicine display, to investigate the possibility of clinical application of 4K monitors. Three different exposures (autoexposure, overexposure and underexposure) images of mammographic phantom were obtained, and six radiologists independently evaluated the images in 5M and 4K without image modulation, by scoring of fibers, groups of specks and masses within the phantom image. The mean score of each object on both monitors was independently analyzed, using t-test and interobserver reliability by intraclass correlation coefficient (ICC) of SPSS. The overall mean scores of fiber, group of specks, and mass in 5M were 4.25, 3.92, and 3.28 respectively, and scores obtained in 4K monitor were 3.81, 3.58, and 3.14, respectively. No statistical difference was seen in scores of fiber and mass between the two monitors at all exposure conditions, but the score of group of specks in 4K was statistically lower in the overall (p = 0.0492) and in underexposure conditions (p = 0.012). The ICC for interobserver reliability was excellent (0.874). Our study suggests that since the mammographic phantom images are appropriate with no significant difference in image quality observed between the two monitors, the 4K monitor could be used for clinical studies. Since this is a small preliminary study using phantom images, the result may differ in actual mammographic images, and subsequent investigation with clinical mammographic images is required.

  7. Workshop 3.5: Closing the gap between exposure and effects in monitoring studies

    Science.gov (United States)

    Tillitt, Donald E.; Papoulias, Diana M.

    2003-01-01

    A major challenge to contaminant monitoring programs is the selection of an appropriate suite of measurements for assessing exposure and effects. Early monitoring programs relied solely on residue analysis to detect the organochlorine compounds that were in use at that time. A shift to the use of more transient, less persistent chemicals required that a new set of tools be developed to determine if an organism had been exposed. This led to the development of cellular and biochemical assays that could indicate the presence of these types of chemicals in biota and the environment. However, it was recognized that measures of contaminant presence alone were insufficient to assess the health of biota. As a result, considerable research began to be directed toward development of diagnostic tools for measuring chemical effects in fish and wildlife. Today, contaminant monitoring programs follow a paradigm for study design that emphasizes not only the use of measures of exposure, but also measures of effect. Using data from our monitoring and research studies for hormonally active substances, we discuss a variety of metrics of exposure and effects and their application to specific chemicals, and the current information gaps. We conclude that although several bioindicators of exposure and effect have been promoted and used, to date there continues to be a poor association between cause and effect for endocrine active substances. In part, this is due to the limited number of diagnostic tools that are available and to a lack of basic toxicological information concerning toxicokinetics and mechanisms of action of hormonally active chemicals in fish and wildlife species. In the foreseeable future, both tissue and environmental residue data, despite the many limitations, will continue to be an important component of monitoring programs for hormonally active chemicals as we continue to develop and validate more specific bioindicators of exposure and effects.

  8. Studies of jet fuel additives using the quartz crystal microbalance and pressure monitoring at 140 C

    Energy Technology Data Exchange (ETDEWEB)

    Zabarnick, S.; Grinstead, R.R. [Univ. of Dayton Research Institute, OH (United States)

    1995-05-01

    The quartz crystal microbalance (QCM) and pressure monitoring are used for the evaluation of jet fuel additives for the improvement of jet fuel thermal stability. The mechanisms of additive behavior are determined by measuring the time dependent deposition with the QCM and oxidation by pressure measurements. Studies at various additive concentrations permits the determination of optimum additive concentrations. Additive packages made of mixtures of antioxidants, detergent/dispersants, and metal deactivators are shown to yield good improvements in thermal stability over a wide range of jet fuel types.

  9. Neutron dosimetry. Environmental monitoring in a BWR type reactor; Dosimetria de neutrones. Monitoreo ambiental en un reactor del tipo BWR

    Energy Technology Data Exchange (ETDEWEB)

    Tavera D, L; Camacho L, M E

    1991-01-15

    The measurements carried out on reactor dosimetry are applied mainly to the study on the effects of the radiation in 108 materials of the reactor; little is on the environmental dosimetry outside of the primary container of BWR reactors. In this work the application of a neutron spectrometer formed by plastic detectors of nuclear traces manufactured in the ININ, for the environmental monitoring in penetrations around the primary container of the unit I of the Laguna Verde central is presented. The neutron monitoring carries out with purposes of radiological protection, during the operational tests of the reactor. (Author)

  10. A communication and information technology infrastructure for real time monitoring and management of type 1 diabetes patients.

    Science.gov (United States)

    Skevofilakas, Marios; Mougiakakou, Stavroula G; Zarkogianni, Konstantia; Aslanoglou, Erika; Pavlopoulos, Sotiris A; Vazeou, Andriani; Bartsocas, Christos S; Nikita, Konstantina S

    2007-01-01

    This paper is focused on the integration of state-of-the-art technologies in the fields of telecommunications, simulation algorithms, and data mining in order to develop a Type 1 diabetes patient's semi to fully-automated monitoring and management system. The main components of the system are a glucose measurement device, an insulin delivery system (insulin injection or insulin pumps), a mobile phone for the GPRS network, and a PDA or laptop for the Internet. In the medical environment, appropriate infrastructure for storage, analysis and visualizing of patients' data has been implemented to facilitate treatment design by health care experts.

  11. Evaluation and Selection of Indicators for Land Degradation and Desertification Monitoring: Types of Degradation, Causes, and Implications for Management

    NARCIS (Netherlands)

    Kairis, O.; Kosmas, C.; Karavitis, C.; Ritsema, C.J.; Salvati, L.; Acikalin, S.; Alcala, M.; Alfama, P.; Atlhopheng, J.; Barrera, J.; Belgacem, A.; Sole-Benet, A.; Brito, J.; Chaker, M.; Chanda, R.; Coelho, C.; Darkoh, M.; Diamantis, I.; Ermolaeva, O.; Fassouli, V.; Fei, W.; Feng, J.; Fernandez, F.; Ferreira, A.; Gokceoglu, C.; Gonzalez, D.; Gungor, H.; Hessel, R.; Juying, J.; Khatteli, H.; Khitrov, N.; Kounalaki, A.; Laouina, A.; Lollino, P.; Lopes, M.; Magole, L.; Medina, L.; Mendoza, M.; Morais, P.; Mulale, K.; Ocakoglu, F.; Ouessar, M.; Ovalle, C.; Perez, C.; Perkins, J.; Pliakas, F.; Polemio, M.; Pozo, A.; Prat, C.; Qinke, Y.; Ramos, A.; Ramos, J.; Riquelme, J.; Romanenkov, V.; Rui, L.; Santaloia, F.; Sebego, R.; Sghaier, M.; Silva, N.; Sizemskaya, M.; Soares, J.; Sonmez, H.; Taamallah, H.; Tezcan, L.; Torri, D.; Ungaro, F.; Valente, S.; Vente, de J.; Zagal, E.; Zeiliguer, A.; Zhonging, W.; Ziogas, A.

    2014-01-01

    Indicator-based approaches are often used to monitor land degradation and desertification from the global to the very local scale. However, there is still little agreement on which indicators may best reflect both status and trends of these phenomena. In this study, various processes of land

  12. Comparison of trap types, placement, and colors for monitoring Anthonomus musculus (Coleoptera: Curculionidae) adults in highbush blueberries

    Science.gov (United States)

    Cranberry weevil, Anthonomus musculus Say (Coleoptera: Curculionidae), is a key pest of highbush blueberries in the northeast USA. To date, however, no trapping system has been developed to successfully monitor this pest. In 2012-2014, studies were conducted in commercial blueberry farms in New Jers...

  13. Diagnostic monitoring of drivetrain in a 5 MW spar-type floating wind turbine using Hilbert spectral analysis

    DEFF Research Database (Denmark)

    Ghane, Mahdi; Nejad, Amir R.; Blanke, Mogens

    2017-01-01

    and condition monitoring approaches; using analytical tools, therefore, is one of the promising approaches in this regard. In this study, forces and moments on the main shaft are obtained from the global response analysis using an aero-hydro-servo-elastic code, SIMO-RIFLEX-AeroDyn. Then, they are utilized...

  14. 6LiF sandwich type detectors for low dose individual monitoring in mixed neutron-photon fields

    International Nuclear Information System (INIS)

    Olko, P.; Budzanowski, M.; Bilski, P.; Burgkhardt, B.; Piesch, E.

    1994-01-01

    ICRP Publication 60 recommends the reduction of the annual dose limit for occupational exposure from 50 to 20 mSv and a doubling of the quality factor for medium energy neutrons. If occupational doses are evaluated every month (which is obligatory e.g. in Germany and in Poland), the individual neutron dosemeter will have to measure neutron doses in the range of 100 μSv. No commercially available, automatic individual dosimetry monitoring system exists that fulfils this requirement. Some of the parameters which influence the evaluation of the neutron dose from readings of TL dosemeters have been studied in order to decrease the variance of the measured neutron signal. In mixed neutron-photon fields, clear separation of the neutron component from the total reading depends also on the uncertainty of the gamma dose measurements. While the thermal albedo neutrons are absorbed mostly at the surface of the 6 LiF detector, the reduction of the detector thickness results in a decrease of its photon sensitivity, while its neutron sensitivity is almost principally maintained. As a consequence, the uncertainty of gamma dose contributes with lower weight to the variance of the evaluated neutron signal. First tests of an optimised 200 μm thick sandwich detector and 0.9 mm thick standard LiF chips were made at low neutron and photon dose ranges using different readers, in order to determine the uncertainty versus dose for different neutron-photon combinations. The conditions under which the new sandwich type detectors may improve albedo neutron dosimetry are demonstrated. (Author)

  15. Remote monitoring technologies for the prevention of metabolic syndrome: the Diabetes and Technology for Increased Activity (DaTA) study.

    Science.gov (United States)

    Stuckey, Melanie; Fulkerson, Robyn; Read, Emily; Russell-Minda, Elizabeth; Munoz, Claudio; Kleinstiver, Peter; Petrella, Robert

    2011-07-01

    Remote monitoring technologies are ideally suited for rural communities with limited access to health care. In an 8-week pilot study, we examined the feasibility of implementing and conducting a technology-intensive intervention in an underserviced rural setting. Our goal was to test the utility of self-monitoring technologies, physical activity, and education as tools to manage health indicators for the development of the cardiovascular complications (CVCs) of type 2 diabetes. The Diabetes and Technology for Increased Activity study was an open single-center study conducted in a community-based research setting. All 24 participants were provided with a Blackberry™ Smartphone, blood pressure monitor, glucometer, and pedometer. Smartphones transmitted measurements and survey results to the database, interfaced participants with the clinical team, and allowed for self-monitoring. Outcomes were improved body composition, improved markers of CVC risk factors, increased daily exercise, and interest in or awareness of lifestyle changes that impact health outcomes. Participants had excellent compliance for measurements, as self-monitoring provided a sense of security that improved from week 4 to week 8. Our team gained substantial insight into the operational requirements of technology-facilitated health care, including redefined hours of service; data reporting, management, and access protocols; and the utility of real-time clinical measures by remote monitoring. We developed an understanding of knowledge translation strategies as well as successful motivational and educational tools. Importantly, remote monitoring technology was found to be feasible and accepted in a rural setting. © 2011 Diabetes Technology Society.

  16. Personnel monitoring system by thermoluminescence dosimeter - a study and review

    International Nuclear Information System (INIS)

    Iyer, V.S.; Alok, M.; Chandel, B.S.

    2018-01-01

    The principle objective of personnel monitoring system is to prevent overexposure and avoid unnecessary exposure of personnel working with various sources of radiation. The adequate system of personnel monitoring must provide for the measurement. evaluation and recording of significant doses accumulated by individuals together with a recording of conditions under which these doses are received

  17. Comparative survey of site and personnel monitoring characteristics for operation of various types of diagnostic-X ray equipment

    International Nuclear Information System (INIS)

    Lyarskij, P.P.; Zol'nikova, N.I.

    1977-01-01

    Diagnostic X-ray machines in present use at medical facilities differ in design and operating parameters, this diversity producing, in turn, a variety of local radiological situations and levels of personnel exposure. Based on radiological safety characterization of working conditions, the authors present a breakdown of contemporary diagnostic X-ray equipment types, based on detailed examination of each group in terms of their associated site monitoring and dosimetry patterns. The paper reports data on personnel exposure levels not only as a function of equipment design and operating characteristics but also according to types of occupational activities for particular medical personnel groups (radiologists, surgeons, anesthesiologists, etc.). Included are health physics data for domestic and foreign X-ray equipment, levels of local and absorbed doses for radiologists, cardiovascular surgeons, neurosurgeons, urologists, traumatologists, anesthesiologists, etc. Measures are recommended for optimizing their activities from the standpoint of radiation safety. (author)

  18. Sticker-type ECG/PPG concurrent monitoring system hybrid integration of CMOS SoC and organic sensor device.

    Science.gov (United States)

    Yongsu Lee; Hyeonwoo Lee; Seunghyup Yoo; Hoi-Jun Yoo

    2016-08-01

    The sticker-type sensor system is proposed targeting ECG/PPG concurrent monitoring for cardiovascular diseases. The stickers are composed of two types: Hub and Sensor-node (SN) sticker. Low-power CMOS SoC for measuring ECG and PPG signal is hybrid integrated with organic light emitting diodes (OLEDs) and organic photo detector (OPD). The sticker has only 2g weight and only consumes 141μW. The optical calibration loop is adopted for maintaining SNR of PPG signal higher than 30dB. The pulse arrival time (PAT) and SpO2 value can be extracted from various body parts and verified comparing with the reference device from 20 people in-vivo experiments.

  19. Microcontroller based motion control interface unit for double slit type beam emittance monitor for H- ion source

    International Nuclear Information System (INIS)

    Holikatti, A.C.; Jain, Rahul; Karnewar, A.K.; Sonawane, B.B.; Maurya, N.K.; Puntambekar, T.A.

    2015-01-01

    The Indian Spallation Neutron Source (ISNS), proposed to be developed at RRCAT, will use a 1 GeV H - linac and an accumulator ring to produce high flux of pulsed neutrons via spallation process. The development activity of front end of 1H - linac for ISNS is under progress at RRCAT, for which a pulsed H - ion source of 50 keV energy, 30 mA current with pulse width of 500 μs has been developed at RRCAT. In this paper, we present the design and development of a microcontroller based motion control interface unit for double slit type beam emittance monitor for the H - ion source. This is an interceptive type of beam diagnostic device, which is used for the quantitative measurement of transverse emittance and beam intensity profile

  20. Hematopoietic stem cell transplantation in Niemann-Pick disease type B monitored by chitotriosidase activity.

    Science.gov (United States)

    Quarello, Paola; Spada, Marco; Porta, Francesco; Vassallo, Elena; Timeus, Fabio; Fagioli, Franca

    2018-02-01

    Here, we report a patient with Niemann-Pick disease type B, with early severe onset of disease and pulmonary involvement, treated with hematopoietic stem cell transplant (HSCT) from a bone marrow matched unrelated donor. We confirm that HSCT is feasible and potentially beneficial for patients with severe phenotype. Noteworthy, we discussed the potential usefulness of the activity of peripheral chitotriosidase for the longitudinal evaluation of HSCT success and effectiveness. © 2017 Wiley Periodicals, Inc.

  1. Comparative study of gas-analyzing systems designed for continuous monitoring of TPP emissions

    Science.gov (United States)

    Kondrat'eva, O. E.; Roslyakov, P. V.

    2017-06-01

    Determining the composition of combustion products is important in terms of both control of emissions into the atmosphere from thermal power plants and optimization of fuel combustion processes in electric power plants. For this purpose, the concentration of oxygen, carbon monoxide, nitrogen, and sulfur oxides in flue gases is monitored; in case of solid fuel combustion, fly ash concentration is monitored as well. According to the new nature conservation law in Russia, all large TPPs shall be equipped with continuous emission monitoring and measurement systems (CEMMS) into the atmosphere. In order to ensure the continuous monitoring of pollutant emissions, direct round-the-clock measurements are conducted with the use of either domestically produced or imported gas analyzers and analysis systems, the operation of which is based on various physicochemical methods and which can be generally used when introducing CEMMS. Depending on the type and purposes of measurement, various kinds of instruments having different features may be used. This article represents a comparative study of gas-analysis systems for measuring the content of polluting substances in exhaust gases based on various physical and physicochemical analysis methods. It lists basic characteristics of the methods commonly applied in the area of gas analysis. It is proven that, considering the necessity of the long-term, continuous operation of gas analyzers for monitoring and measurement of pollutant emissions into the atmosphere, as well as the requirements for reliability and independence from aggressive components and temperature of the gas flow, it is preferable to use optical gas analyzers for the aforementioned purposes. In order to reduce the costs of equipment comprising a CEMMS at a TPP and optimize the combustion processes, electrochemical and thermomagnetic gas analyzers may also be used.

  2. Radiation monitoring

    International Nuclear Information System (INIS)

    Larsson, L.Eh.; B'yuli, D.K.; Karmikel, Dzh.Kh.E.

    1985-01-01

    Recommendations on radiation monitoring of personnel, used medical ionizing radiation source, are given. The necessity to carry out radiation monitoring of situation at medical personnel's positions and personnel dosimetry is marked. It is convenient to subdivide radiation monitoring into 3 types: usual, surgical and special. Usual monitoring is connected with current work; surgical monitoring is carried out to receive information during a concrete operation; special monitoring is used to detect possible deviation from standard conditions of work or when suspecting them

  3. Aerosol monitoring during work inside the 'object shelter': Analysis of dispersion and concentration for different work types

    International Nuclear Information System (INIS)

    Aryasov, P.; Nechaev, S.; Tsygankov, N.; Dmitrienko, A.

    2007-01-01

    Results of aerosol monitoring during work inside the object shelter (OS) are presented. Taking into account the fact that dispersion of the aerosol is one of the main factors affecting internal dose [Annals of the ICRP, ICRP Publication 66, Human Respiratory Tract Model for Radiological Protection, Pergamon Press, 1993], principal task of the investigation was the determination of the aerodynamic diameter (AD) distribution of the radioactive aerosol. Special attention was paid to transuranium elements' content in the aerosol since they are the major dose-producing radionuclides for the OS conditions. At present, work on stabilization of unstable constructions of the OS is in the active stage. Most of the work inside the OS leads to increased generation of radioactive aerosols. This work is carried out in the highly contaminated premises of the OS, where radioactive situation has been formed during the accident. Present work contains earliest results of the aerosol monitoring program for the period from September 2005 untill February 2006. Data obtained shows that for most types of work, radionuclides mainly located in the coarse aerosol fraction, activity median aerodynamic diameter (AMAD) range 8-12 μm. Work on the program continues at present time (actual data accumulation and analysis). Further widening of the program with the goal of type of material determination is described

  4. Continuous glucose monitoring for patients with type 1 diabetes and impaired awareness of hypoglycaemia (IN CONTROL): a randomised, open-label, crossover trial

    NARCIS (Netherlands)

    van Beers, Cornelis A. J.; DeVries, J. Hans; Kleijer, Susanne J.; Smits, Mark M.; Geelhoed-Duijvestijn, Petronella H.; Kramer, Mark H. H.; Diamant, Michaela; Snoek, Frank J.; Serné, Erik H.

    2016-01-01

    Patients with type 1 diabetes who have impaired awareness of hypoglycaemia have a three to six times increased risk of severe hypoglycaemia. We aimed to assess whether continuous glucose monitoring (CGM) improves glycaemia and prevents severe hypoglycaemia compared with self-monitoring of blood

  5. Study of radiation portal monitor and its application to metal recycling industry

    International Nuclear Information System (INIS)

    Pujol, L.; Lara-Calleja, S.; Suarez-Navarro, M. J.; Gonzalez-Gonzalez, J. A.

    2009-01-01

    The industry of the iron and the steel in one of the most important sectors in Spain for its economic development. the recycling of metallic materials as well as the import of metallic scrap is very significant. Several reports on accidental dispersion or smelting of radioactive sources in metal recycling industries confirm the possibility that radioactive material might be mixed with scrap. In consequence, this type of accident shows the necessity of a rigorous and specific radiation control of the sector. The control of these materials with radioactive content can be carried out with radiation portal monitors installed at the entrance of these industries. The detection of radioactive materials presents special features as the continuous background acquisition or the minimisation of the relatively large number of innocent/nuisance detections. In the present work, we study a radiation portal monitor, the FHT-1388-T Thermo-Eberline. This is one of the usual radiation portal systems installed at the entrance of the metal recycling industry. Se study the characteristics and parameters of this portal monitor to optimise its use. furthermore, we propose some rapid tests for radiation portal systems in metal recycling industry. (Author) 16 refs

  6. Management and monitoring recommendations for the use of eliglustat in adults with type 1 Gaucher disease in Europe.

    Science.gov (United States)

    Belmatoug, Nadia; Di Rocco, Maja; Fraga, Cristina; Giraldo, Pilar; Hughes, Derralynn; Lukina, Elena; Maison-Blanche, Pierre; Merkel, Martin; Niederau, Claus; Plӧckinger, Ursula; Richter, Johan; Stulnig, Thomas M; Vom Dahl, Stephan; Cox, Timothy M

    2017-01-01

    In Gaucher disease, diminished activity of the lysosomal enzyme, acid β-glucosidase, leads to accumulation of glucosylceramides and related substrates, primarily in the spleen, liver, and bone marrow. Eliglustat is an oral substrate reduction therapy approved in the European Union and the United States as a first-line treatment for adults with type 1 Gaucher disease who have compatible CYP2D6 metabolism phenotypes. A European Advisory Council of experts in Gaucher disease describes the characteristics of eliglustat that are distinct from enzyme augmentation therapy (the standard of care) and miglustat (the other approved substrate reduction therapy) and recommends investigations and monitoring for patients on eliglustat therapy within the context of current recommendations for Gaucher disease management. Eliglustat is a selective, potent inhibitor of glucosylceramide synthase, the enzyme responsible for biosynthesis of glucosylceramides which accumulate in Gaucher disease. Extensive metabolism of eliglustat by CYP2D6, and, to a lesser extent, CYP3A of the cytochrome P450 pathway, necessitates careful consideration of the patient's CYP2D6 metaboliser status and use of concomitant medications which share metabolism by these pathways. Guidance on specific assessments and monitoring required for eliglustat therapy, including an algorithm to determine eligibility for eliglustat, are provided. As a first-line therapy for type 1 Gaucher disease, eliglustat offers eligible patients a daily oral therapy alternative to biweekly infusions of enzyme therapy. Physicians will need to carefully assess individual Gaucher patients to determine their appropriateness for eliglustat therapy. The therapeutic response to eliglustat and use of concomitant medications will require long-term monitoring. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  7. [Safety study of long-term video-electroencephalogram monitoring].

    Science.gov (United States)

    Ley, M; Vivanco, R; Massot, A; Jiménez, J; Roquer, J; Rocamora, R

    2014-01-01

    The increased morbidity and mortality and poorer quality of life associated with drug-resistant epilepsy justify admitting patients to epilepsy monitoring units (EMU). These units employ methods that promote the occurrence of seizures, which involves a risk of secondary adverse events. The aim of our study is to characterise and quantify these adverse events in a Spanish EMU. A descriptive, longitudinal and retrospective study of patients admitted consecutively to our EMU. Patients admitted due to status epilepticus, clusters of seizures, or as participants in a clinical trial were excluded. We included 175 patients, of whom 92.1% (161) did not suffer any adverse events. Status epilepticus was present in 3.4% (6); 1.7% (3) had traumatic injury, 1.7% (3) had interictal or postictal psychosis, and 1.1% (2) had cardiorespiratory impairment. There were no risk factors associated with these adverse events. The most frequently-identified adverse events were status epilepticus, traumatic injury, interictal or postictal psychosis, and cardiorespiratory disorders. The frequency of these adverse events was similar to that seen in international literature. The complications detected do not contraindicate VEEGM. Copyright © 2012 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

  8. Liquid-type Botulinum Toxin Type A in Adductor Spasmodic Dysphonia: A Prospective Pilot Study.

    Science.gov (United States)

    Cha, Wonjae; Jang, Jeon Yeob; Wang, Soo-Geun; Kang, Ji-Heon; Jo, Min-Gyu

    2017-05-01

    Botulinum toxin (BTX) has been widely used to treat adductor spasmodic dysphonia (ADSD). Most commercially available forms of BTX require reconstitution before use, which may increase the risk of contamination and requires careful titration. Recently, a liquid-type BTX type A (BTX-A) has been developed, which should simplify the procedure and enhance its efficacy. Herein, we present a prospective pilot study to investigate the efficacy and safety of liquid-type BTX-A in the treatment of ADSD. Twenty-six consecutive liquid-type BTX-A injections were performed in 12 patients with ADSD. We included as a control group 34 consecutive patients with ADSD who had previously undergone 52 vocal fold injection procedures with freeze-dried-type BTX-A. All patients in both groups had improvement of symptoms related to ADSD and period of normal voice. Most patients experienced breathiness, and the onset time, the peak response time, and the duration of breathiness were similar in both groups. The duration of effect (days) was 96.96 ± 18.91 and 77.38 ± 18.97 in the freeze-dried-type and the liquid-type groups, and the duration of benefit (days) was 80.02 ± 18.24 and 62.69 ± 19.73 in the freeze-dried-type and the liquid-type groups. To compare the efficacy between the freeze-dried-type and the liquid-type BTX-A, the sessions of the unilateral vocal fold injection were included and were categorized as group A (1 ~ 2 units BTX-A) and group B (2 ~ 3 units BTX-A), according to the dose per vocal fold. There was no significant difference of effect time between freeze-dried-type and liquid-type BTX-A groups. No adverse events related to BTX or vocal fold injection were reported. Liquid-type BTX-A is safe and effective for the treatment of spasmodic dysphonia. With the advantages of simple preparation, storage, and reuse and animal protein-free constituents, liquid-type BTX-A may be a good option in the treatment of spasmodic dysphonia. Copyright © 2017 The

  9. The Potential of Computational Fluid Dynamics Simulation on Serial Monitoring of Hemodynamic Change in Type B Aortic Dissection

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Simon C. H., E-mail: simonyu@cuhk.edu.hk; Liu, Wen [The Chinese University of Hong Kong, Department of Imaging and Interventional Radiology, Prince of Wales Hospital (Hong Kong); Wong, Randolph H. L.; Underwood, Malcolm [The Chinese University of Hong Kong, Division of Cardiothoracic Surgery, Department of Surgery, Prince of Wales Hospital (Hong Kong); Wang, Defeng [The Chinese University of Hong Kong, Department of Imaging and Interventional Radiology, Prince of Wales Hospital (Hong Kong)

    2016-08-15

    PurposeWe aimed to assess the potential of computational fluid dynamics simulation (CFD) in detecting changes in pressure and flow velocity in response to morphological changes in type B aortic dissection.Materials and MethodsPressure and velocity in four morphological models of type B aortic dissection before and after closure of the entry tear were calculated with CFD and analyzed for changes among the different scenarios. The control model (Model 1) was patient specific and built from the DICOM data of CTA, which bore one entry tear and three re-entry tears. Models 2–4 were modifications of Model 1, with two re-entry tears less in Model 2, one re-entry tear more in Model 3, and a larger entry tear in Model 4.ResultsThe pressure and velocity pertaining to each of the morphological models were unique. Changes in pressure and velocity findings were accountable by the changes in morphological features of the different models. There was no blood flow in the false lumen across the entry tear after its closure, the blood flow direction across the re-entry tears was reversed after closure of the entry tear.ConclusionCFD simulation is probably useful to detect hemodynamic changes in the true and false lumens of type B aortic dissection in response to morphological changes, it may potentially be developed into a non-invasive and patient-specific tool for serial monitoring of hemodynamic changes of type B aortic dissection before and after treatment.

  10. Specialist Cohort Event Monitoring studies: a new study method for risk management in pharmacovigilance.

    Science.gov (United States)

    Layton, Deborah; Shakir, Saad A W

    2015-02-01

    The evolving regulatory landscape has heightened the need for innovative, proactive, efficient and more meaningful solutions for 'real-world' post-authorization safety studies (PASS) that not only align with risk management objectives to gather additional safety monitoring information or assess a pattern of drug utilization, but also satisfy key regulatory requirements for marketing authorization holder risk management planning and execution needs. There is a need for data capture across the primary care and secondary care interface, or for exploring use of new medicines in secondary care to support conducting PASS. To fulfil this need, event monitoring has evolved. The Specialist Cohort Event Monitoring (SCEM) study is a new application that enables a cohort of patients prescribed a medicine in the hospital and secondary care settings to be monitored. The method also permits the inclusion of a comparator cohort of patients receiving standard care, or another counterfactual comparator group, to be monitored concurrently, depending on the study question. The approach has been developed in parallel with the new legislative requirement for pharmaceutical companies to undertake a risk management plan as part of post-authorization safety monitoring. SCEM studies recognize that the study population comprises those patients who may have treatment initiated under the care of specialist health care professionals and who are more complex in terms of underlying disease, co-morbidities and concomitant medications than the general disease population treated in primary care. The aims of this paper are to discuss the SCEM new-user study design, rationale and features that aim to address possible bias (such as selection bias) and current applications.

  11. Study on loss detection algorithms using tank-monitoring data

    International Nuclear Information System (INIS)

    Suzuki, Mitsutoshi; Hori, Masato; Nagaoka, Shinichi; Kimura, Takashi

    2009-01-01

    An application of solution monitoring to material balance evaluation has been investigated with actual data from the Solution Monitoring Management System (SMMS) in the Tokai Reprocessing Plant (TRP). Loss detection capabilities of the proposed multivariate statistical methods are examined numerically for a simulated loss corresponding to parameters of a significant quantity in the wait mode. Multiscale statistical analysis as well as multivariate cumulative sum analysis are successfully used to demonstrate the protracted-loss detection. Because the actual tank data is composed of records in both the wait and transfer modes, the tank-to-tank transferring data is extracted from the sequence of monitoring data, and the error model effectiveness is evaluated in comparison with calculations. Although the data taken from the SMMS does not describe the entire solution process, an extended application of solution monitoring to the nuclear material accounting is advanced using the plant data, and future research subjects are described. (author)

  12. Mobile communication using a mobile phone with a glucometer for glucose control in Type 2 patients with diabetes: as effective as an Internet-based glucose monitoring system.

    Science.gov (United States)

    Cho, Jae-Hyoung; Lee, Hye-Chung; Lim, Dong-Jun; Kwon, Hyuk-Sang; Yoon, Kun-Ho

    2009-01-01

    A mobile phone with a glucometer integrated into the battery pack (the 'Diabetes Phone') was launched in Korea in 2003. We compared its effect on management of type 2 diabetes to the Internet-based glucose monitoring system (IBGMS), which had been studied previously. We conducted a randomized trial involving 69 patients for three months. Participants were assigned to an Internet group or a phone group. The phone group communicated with medical staff through the mobile phone only. Their glucose-monitoring data were automatically transferred to individual, web-based charts and they received medical recommendations by short message service. The Internet group used the IBGMS. There were no significant differences between the groups at baseline. After three months' intervention, HbA(1c) levels of both groups had decreased significantly, from 7.6% to 6.9% for the Internet group and from 8.3% to 7.1% for the phone group (P glucose control as the previously-studied Internet-based monitoring system and it was good for patient satisfaction and adherence.

  13. Can verbal instruction enhance the recall of an everyday task and promote error-monitoring in people with dementia of the Alzheimer-type?

    Science.gov (United States)

    Balouch, Sara; Rusted, Jennifer M

    2017-03-01

    People with dementia of the Alzheimer-type (DAT) have difficulties with performing everyday tasks, and error awareness is poor. Here we investigate whether recall of actions and error monitoring in everyday task performance improved when they instructed another person on how to make tea. In this situation, both visual and motor cues are present, and attention is sustained by the requirement to keep instructing. The data were drawn from a longitudinal study recording performance in four participants with DAT, filmed regularly for five years in their own homes, completing three tea-making conditions: performed-recall (they made tea themselves); instructed-recall (they instructed the experimenter on how to make tea); and verbal-recall (they described how to make tea). Accomplishment scores (percentage of task they correctly recalled), errors and error-monitoring were coded. Task accomplishment was comparable in the performed-recall and instructed-recall conditions, but both were significantly better than task accomplishment in the verbal-recall condition. Third person instruction did not improve error-monitoring. This study has implications for everyday task rehabilitation for people with DAT.

  14. Factors Associated with Visual Fatigue from Curved Monitor Use: A Prospective Study of Healthy Subjects.

    Directory of Open Access Journals (Sweden)

    Haeng Jin Lee

    Full Text Available To investigate the factors associated with visual fatigue using monitors with various radii of curvature.Twenty normal healthy adults (8 men, 12 women; mean age, 26.2 ± 2.5 years prospectively watched five types of monitors including flat, 4000R, 3000R, 2000R, and 1000R curved monitors for 30 min. An experienced examiner measured the ophthalmological factors including near point of accommodation (NPA, near point of convergence (NPC, refraction, parameters during pupil response at light and saccadic movement just before and after the visual tasks. The questionnaires about subjective ocular symptoms were also investigated just before and after the visual tasks.The NPA increased after the visual tasks with a flat monitor compared with the curved monitors, with the 1000R curved monitor showing the smallest change (p = 0.020. The NPC increased for every monitor after the visual tasks; the largest increase occurred with the flat monitor (p = 0.001. There was no difference in refractive error, pupil response, or saccadic movement in the comparison of before and after the visual tasks. Among the nine factors in the questionnaire, the score of "eye pain" was significantly higher for the flat monitor versus the 1000R curved monitor after the visual tasks (p = 0.034.We identified NPA, NPC, and eye pain as factors associated with visual fatigue. Also, the curvature of the monitor was related to the visual fatigue.

  15. [Spermatogonia types in tepezcuintle (Cuniculus paca). Ultrastructural study].

    Science.gov (United States)

    Ureña, F; Bolaños, R; Rojas, N; Suárez, R; Quesada, R

    1988-11-01

    Ultrastructural studies of different types of spermatogonia by thin section techniques and transmission electron microscopy showed that Cuniculus paca has two types of Type A spermatogonia (A-O and A-1). Samples were taken at different stages of the cycle in the seminiferous tubule epithelium presented a similar pattern as those of other rodents. Type B spermatogonia are similar to those of the rat, the difference being that the heterochromatic zones are larger and more numerous. Both characteristics differentiate them from preleptotenic spermatocytes.

  16. Study concerning an integrated radiation monitoring systems for nuclear facilities

    International Nuclear Information System (INIS)

    Oprea, I.; Oprea, M.; Stoica, M.; Cerga, V.; Pirvu, V; Badea, E.

    1996-01-01

    This paper presents an integrated radiation monitoring system designed to assess the effects of nuclear accidents and to provide a basis for making right decisions and countermeasures in order to reduce health damages. The system implies a number of stationary monitoring equipment, data processing unit and a communication network. The system meets the demands of efficiency and reliability, providing the needed tools to easily create programs able to process simple input data filling the information management system. (author). 10 refs

  17. Field testing plan for unsaturated zone monitoring and field studies

    International Nuclear Information System (INIS)

    Young, M.H.; Wierenga, P.J.; Warrick, A.W.

    1996-10-01

    The University of Arizona, in cooperation with the Bureau of Economic Geology at The University of Texas at Austin, and Stephens and Associates in Albuquerque, New Mexico has developed a field testing plan for evaluating subsurface monitoring systems. The U.S. Nuclear Regulatory Commission has requested development of these testing plans for low-level radioactive waste disposal sites (LLW) and for monitoring at decommissioned facilities designated under the open-quotes Site Decommissioning Management Planclose quotes (SDMP). The tests are conducted on a 50 m by 50 m plot on the University of Arizona's Maricopa Agricultural Center. Within the 50 m by 50 m plot one finds: (1) an instrumented buried trench, (2) monitoring islands similar to those proposed for the Ward Valley, California LLW Facility, (3) deep borehole monitoring sites, (4) gaseous transport monitoring, and (5) locations for testing non-invasive geophysical measurement techniques. The various subplot areas are instrumented with commercially available instruments such as neutron probes, time domain reflectometry probes, tensiometers, psychrometers, heat dissipation sensors, thermocouples, solution samplers, and cross-hole geophysics electrodes. Measurement depths vary from ground surface to 15 m. The data from the controlled flow and transport experiments, conducted over the plot, will be used to develop an integrated approach to long-term monitoring of the vadose zone at waste disposal sites. The data will also be used to test field-scale flow and transport models. This report describes in detail the design of the experiment and the methodology proposed for evaluating the data

  18. Use of aquatic bryophytes as bio monitors for radioactive studies

    International Nuclear Information System (INIS)

    Damianova, A.; Penev, I.; Drenska, M.

    2006-01-01

    As a widespread water moss Fontinalis antipyretics is frequently used as a biomonitor for trace elements pollution in lakes and running waters. The purpose of this study is to use Fontinalis antipyretics as a tool for monitoring of radioactivity in waters from different rivers (Musalenska Bistriza, Iskar, Maritza, etc.) in Rila Mountain. The radioactivity of aquatic moss, water samples and sediments were measured using HPG detector with the parameters FWHM 2 kev at 6 0Co efficiency 35% with low background. The dose rate measurements (μR/h) show different values according to the place of sampling and reflect the present ecological status of the river ecosystems. The ongoing measurements will allowed the absolute value of 1 37Cs in bryophytes to be determined and eventually some seasonal variations to be observed. A special interest is whether the measured activity is accidental or is as a consequence of a long time accumulation in the bryophytes. In this case they could probably be used for water purification. On that basis the bryophytes could be used for controlling radioactivity of river ecosystems even in high-mountain difficult accessible places replacing the transportation of large volumes of water

  19. Biotelemetric Wireless Intracranial Pressure Monitoring: An In Vitro Study

    Directory of Open Access Journals (Sweden)

    Mohammad H. Behfar

    2015-01-01

    Full Text Available Assessment of intracranial pressure (ICP is of great importance in management of traumatic brain injuries (TBIs. The existing clinically established ICP measurement methods require catheter insertion in the cranial cavity. This increases the risk of infection and hemorrhage. Thus, noninvasive but accurate techniques are attractive. In this paper, we present two wireless, batteryless, and minimally invasive implantable sensors for continuous ICP monitoring. The implants comprise ultrathin (50 μm flexible spiral coils connected in parallel to a capacitive microelectromechanical systems (MEMS pressure sensor. The implantable sensors are inductively coupled to an external on-body reader antenna. The ICP variation can be detected wirelessly through measuring the reader antenna’s input impedance. This paper also proposes novel implant placement to improve the efficiency of the inductive link. In this study, the performance of the proposed telemetry system was evaluated in a hydrostatic pressure measurement setup. The impact of the human tissues on the inductive link was simulated using a 5 mm layer of pig skin. The results from the in vitro measurement proved the capability of our developed sensors to detect ICP variations ranging from 0 to 70 mmHg at 2.5 mmHg intervals.

  20. Comparative study T-type and I-type layout of PWR nuclear power plants

    International Nuclear Information System (INIS)

    Eko Rudi Iswanto and Siti Alimah

    2010-01-01

    Determining plant layout is one of the five major stages during the life time of a nuclear power plant. Some important factors that affect in the selecting of plant layout are availability of infrastructure, economic aspects, social aspects, public and environment safety, and also easy to do. Another factor to be considered is requirements as seismic design, which refers to the principles of good security workers, communities and the environment of radiological risks. There are many layout types of nuclear power plant, two of them are T-type layout and I-type layout. Each type of the plant layout has advantage and disadvantage, therefore this study is to understand them. Good layout is able to provide a high level of security against earthquakes. In term of earthquake design, I-type layout has a higher security level than T-type layout. Therefore, I-type layout can be a good choice for PWR nuclear power plants 1000 MWe that will be built in Indonesia. (author)

  1. Effect of Financial Incentives on Glucose Monitoring Adherence and Glycemic Control Among Adolescents and Young Adults With Type 1 Diabetes: A Randomized Clinical Trial.

    Science.gov (United States)

    Wong, Charlene A; Miller, Victoria A; Murphy, Kathryn; Small, Dylan; Ford, Carol A; Willi, Steven M; Feingold, Jordyn; Morris, Alexander; Ha, Yoonhee P; Zhu, Jingsan; Wang, Wenli; Patel, Mitesh S

    2017-12-01

    Glycemic control often deteriorates during adolescence and the transition to young adulthood for patients with type 1 diabetes. The inability to manage type 1 diabetes effectively during these years is associated with poor glycemic control and complications from diabetes in adult life. To determine the effect of daily financial incentives on glucose monitoring adherence and glycemic control in adolescents and young adults with type 1 diabetes. The Behavioral Economic Incentives to Improve Glycemic Control Among Adolescents and Young Adults With Type 1 Diabetes (BE IN CONTROL) study was an investigator-blinded, 6-month, 2-arm randomized clinical trial conducted between January 22 and November 2, 2016, with 3-month intervention and follow-up periods. Ninety participants (aged 14-20) with suboptimally controlled type 1 diabetes (hemoglobin A1c [HbA1c] >8.0%) were recruited from the Diabetes Center for Children at the Children's Hospital of Philadelphia. All participants were given daily blood glucose monitoring goals of 4 or more checks per day with 1 or more level within the goal range (70-180 mg/dL) collected with a wireless glucometer. The 3-month intervention consisted of a $60 monthly incentive in a virtual account, from which $2 was subtracted for every day of nonadherence to the monitoring goals. During a 3-month follow-up period, the intervention was discontinued. The primary outcome was change in HbA1c levels at 3 months. Secondary outcomes included adherence to glucose monitoring and change in HbA1c levels at 6 months. All analyses were by intention to treat. Of the 181 participants screened, 90 (52 [57.8%] girls) were randomized to the intervention (n = 45) or control (n = 45) arms. The mean (SD) age was 16.3 (1.9) years. The intervention group had significantly greater adherence to glucose monitoring goals in the incentive period (50.0% vs 18.9%; adjusted difference, 27.2%; 95% CI, 9.5% to 45.0%; P = .003) but not in the follow-up period (15

  2. Strategy for assessing occupational radiation monitoring data from many facilities for use in epidemiologic studies

    International Nuclear Information System (INIS)

    Strom, D.J.

    1983-01-01

    A comprehensive strategy for dose assessment at US DOE facilities was developed. The strategy includes a determination of what data are available at each site, and what form they are in for the various times and types of monitoring. At the same time, information is gathered regarding the radiation hazards as a function of time, in order to judge the adequacy of monitoring. Information is collected on documentation of the personnel monitoring programs at each site. After this information is compiled and analyzed, site-specific data retrieval criteria and methods are finalized and meshed with general criteria and methods. Concurrently, Standard Assessment Procedures (SAP) are developed. Detailed steps are presented for the inference of annual doses from the kinds of occupational records found at DOE facilities, and when such inferences are too uncertain to be useful, guidance is provided for use of results in the control of confounding by undetermined exposures. The strategy was tested on a facility in the US Department of Energy (DOE) Health and Mortality Study, the Y-12 plant in Oak Ridge, Tennessee. 156 references, 53 figures, 45 tables

  3. Direct Application of Rep-PCR on Type I Sourdough Matrix to Monitor the Dominance and Persistence of a Lactobacillus plantarum Starter Throughout Back-Slopping.

    Science.gov (United States)

    Dolci, Paola; Cocolin, Luca

    2017-08-01

    This study describes the optimization and application of repetitive element-PCR (rep-PCR) technique directly on microbial DNA extracted from type I sourdoughs for fast monitoring of a Lb. plantarum starter strain (P1FMC) throughout daily back-slopping. The challenge was to follow and study the performance of a starter culture directly in sourdoughs without cultivation on selective media. The extraction of good quality microbial DNA suitable for amplification from a complex matrix such as dough was the first target. In addition, the objective to obtain a clear rep-PCR profile referable to a specific starter strain among a microbial community was pursued. Co-inoculum trials, in flour matrix, with Lb. plantarum P1FMC and L. lactis LC71 strains and, subsequently, type I sourdough back-slopping trials were performed. The rep-PCR amplification profiles obtained were clearly referable to that of Lb. plantarum P1FMC starter in both co-inoculum trials (also when it was present with one order of magnitude less with respect to L. lactis LC71) and back-slopping trials where it dominated the fermentation process with loads of 10 8 cfu g -1 and prevailed on the autochthonous microbiota. Thus, the approach proposed in this paper could be considered a methodological advancement, based on a culture-independent one-step rep-PCR, suitable for fast monitoring of starter performance. © 2017 Institute of Food Technologists®.

  4. Continuous glucose monitoring and HbA1c in the evaluation of glucose metabolism in children at high risk for type 1 diabetes mellitus.

    Science.gov (United States)

    Helminen, Olli; Pokka, Tytti; Tossavainen, Päivi; Ilonen, Jorma; Knip, Mikael; Veijola, Riitta

    2016-10-01

    Continuous glucose monitoring (CGM) parameters, self-monitored blood glucose (SMBG), HbA1c and oral glucose tolerance test (OGTT) were studied during preclinical type 1 diabetes mellitus. Ten asymptomatic children with multiple (⩾2) islet autoantibodies (cases) and 10 age and sex-matched autoantibody-negative controls from the Type 1 Diabetes Prediction and Prevention (DIPP) Study were invited to 7-day CGM with Dexcom G4 Platinum Sensor. HbA1c and two daily SMBG values (morning and evening) were analyzed. Five-point OGTTs were performed and carbohydrate intake was assessed by food records. The matched pairs were compared with the paired sample t-test. The cases showed higher mean values and higher variation in glucose levels during CGM compared to the controls. The time spent ⩾7.8mmol/l was 5.8% in the cases compared to 0.4% in the controls (p=0.040). Postprandial CGM values were similar except after the dinner (6.6mmol/l in cases vs. 6.1mmol/l in controls; p=0.023). When analyzing the SMBG values higher mean level, higher evening levels, as well as higher variation were observed in the cases when compared to the controls. HbA1c was significantly higher in the cases [5.7% (39mmol/mol) vs. 5.3% (34mmol/mol); p=0.045]. No differences were observed in glucose or C-peptide levels during OGTT. Daily carbohydrate intake was slightly higher in the cases (254.2g vs. 217.7g; p=0.034). Glucose levels measured by CGM and SMBG are useful indicators of dysglycemia during preclinical type 1 diabetes mellitus. Increased evening glucose values seem to be common in children with preclinical type 1 diabetes mellitus. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  5. A study on online monitoring system development using empirical models

    Energy Technology Data Exchange (ETDEWEB)

    An, Sang Ha

    2010-02-15

    Maintenance technologies have been progressed from a time-based to a condition-based manner. The fundamental idea of condition-based maintenance (CBM) is built on the real-time diagnosis of impending failures and/or the prognosis of residual lifetime of equipment by monitoring health conditions using various sensors. The success of CBM, therefore, hinges on the capability to develop accurate diagnosis/prognosis models. Even though there may be an unlimited number of methods to implement models, the models can normally be classified into two categories in terms of their origins: using physical principles or historical observations. I have focused on the latter method (sometimes referred as the empirical model based on statistical learning) because of some practical benefits such as context-free applicability, configuration flexibility, and customization adaptability. While several pilot-scale systems using empirical models have been applied to work sites in Korea, it should be noticed that these do not seem to be generally competitive against conventional physical models. As a result of investigating the bottlenecks of previous attempts, I have recognized the need for a novel strategy for grouping correlated variables such that an empirical model can accept not only statistical correlation but also some extent of physical knowledge of a system. Detailed examples of problems are as follows: (1) missing of important signals in a group caused by the lack of observations, (2) problems of signals with the time delay, (3) problems of optimal kernel bandwidth. In this study an improved statistical learning framework including the proposed strategy and case studies illustrating the performance of the method are presented.

  6. Study on intermediate frequency power supply automatic monitor system

    International Nuclear Information System (INIS)

    Wang Yuntong; Xu Bin

    2007-06-01

    A new design project of the automatic monitor system for the intermediate frequency power supply system by using the communication server is put for- ward and the realizing principle method and the key technique are clarified in detail. This system made use of the conversion function with the series communication server's control, realized the data collecting function by the double machine backup and redundancy. The new network system adopted the photoelectric-insulated-communication connect device and the diagnosis technique, increased the anti-interference ability, the communication adopted the technique by the alarm information sending out in first and circularly repeating, the slowly speed is overcame in the original monitor network system, and strengthened the celerity of the monitor system and the reliability of the alarm report. After the new monitor system running, the result shows that the functions is more perfect than the original monitor system, the usage is more convenient, have the higher and dependable stability, the report of alarm is more quickly, and is convenient for the analysis after the trouble, at the same time, the system still have the strong ability and value to expand. (authors)

  7. Design and array signal suggestion of array type pulsed eddy current probe for health monitoring of metal tubes

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Young Kil [Dept. of Electrical Engineering, Kunsan National University, Kunsan (Korea, Republic of)

    2015-10-15

    An array type probe for monitoring metal tubes is proposed in this paper which utilizes peak value and peak time of a pulsed eddy current(PEC) signal. The probe consists of an array of encircling coils along a tube and the outside of coils is shielded by ferrite to prevent source magnetic fields from directly affecting sensor signals since it is the magnetic fields produced by eddy currents that reflect the condition of metal tubes. The positions of both exciter and sensor coils are consecutively moved automatically so that manual scanning is not necessary. At one position of send-receive coils, peak value and peak time are extracted from a sensor PEC signal and these data are accumulated for all positions to form an array type peak value signal and an array type peak time signal. Numerical simulation was performed using the backward difference method in time and the finite element method for spatial analysis. Simulation results showed that peak value increases and the peak appears earlier as the defect depth or length increases. The proposed array signals are shown to be excellent in reflecting the defect location as well as variations of defect depth and length within the array probe.

  8. Brief Computer-Delivered Intervention to Increase Parental Monitoring in Families of African American Adolescents with Type 1 Diabetes: A Randomized Controlled Trial.

    Science.gov (United States)

    Ellis, Deborah A; Idalski Carcone, April; Ondersma, Steven J; Naar-King, Sylvie; Dekelbab, Bassem; Moltz, Kathleen

    2017-06-01

    African American adolescents with type 1 diabetes (T1D) are at elevated risk for poor diabetes management and metabolic control. Parental supervision and monitoring of adolescent diabetes management have been shown to promote better diabetes management among adolescents, but parents typically decrease their oversight during the transition to independent diabetes care. The purpose of the study was to conduct a randomized clinical trial to test the feasibility and efficacy of a three-session, computer-delivered motivational intervention (The 3Ms) to promote increased parental monitoring among primary caregivers of young African American adolescents with T1D. The intervention was brief and optimized for delivery during routine diabetes clinic visits. Sixty-seven adolescents with T1D aged 11-14 and their primary caregiver were randomly assigned to one of three arms: adolescent and parent motivational intervention (Arm 1), adolescent control and parent motivational intervention (Arm 2), or adolescent and parent control (Arm 3). Intervention effects were assessed 1 month after intervention completion. Parents in Arm 1 and Arm 2 had significant increases in knowledge of the importance of monitoring adolescents' diabetes care. Parents in Arm 2 also had trend to significant increases in direct observation and monitoring of adolescent diabetes care, and adolescents in Arm 2 had significant improvements in glycemic control. Findings from the present study provide preliminary support for the efficacy of a brief, computer-delivered parenting intervention for improving family management practices and adolescent health outcomes among African American adolescents with T1D and their caregivers.

  9. Factors Affecting Mobile Diabetes Monitoring Adoption Among Physicians : Questionnaire Study and Path Model

    NARCIS (Netherlands)

    Okazaki, Shintaro; Castaneda, José Alberto; Sanz, Silvia; Henseler, Jörg

    2012-01-01

    Background: Patients with type 1 and type 2 diabetes often find it difficult to control their blood glucose level on a daily basis because of distance or physical incapacity. With the increase in Internet-enabled smartphone use, this problem can be resolved by adopting a mobile diabetes monitoring

  10. Short-term use of continuous glucose monitoring system adds to glycemic control in young type 1 diabetes mellitus patients in the long run: A clinical trial

    Directory of Open Access Journals (Sweden)

    Bukara-Radujković Gordana

    2011-01-01

    Full Text Available Background/Aim. Balancing strict glycemic control with setting realistic goals for each individual child and family can optimize growth, ensure normal pubertal development and emotional maturation, and control long term complications in children with type 1 diabetes (T1DM. The aim of this study was to evaluate the efficacy of short-term continuous glucose monitoring system (CGMS application in improvement of glycemic control in pediatric type 1 diabetes mellitus (T1DM patients. Methods. A total of 80 pediatric T1DM patients were randomly assigned into the experimental and the control group. The experimental group wore CGMS sensor for 72 hours at the beginning of the study. Self-monitored blood glucose (SMBG levels and hemoglobin A1c (HbA1c levels were obtained for both groups at baseline, and at 3 and 6 months. Results. There was a significant improvement in HbA1c (p < 0.001, in both the experimental and the control group, without a significant difference between the groups. Nevertheless, after 6 months the improvement of mean glycemia was noticed only in the experimental group. This finding was accompanied with a decrease in the number of hyperglycemic events and no increase in the number of hypoglycemic events in the experimental group. Conclusions. The results suggest that the CGMS can be considered as a valuable tool in treating pediatric T1DM patients, however further research is needed to more accurately estimate to what extent, if any, it outperforms intensive self-monitoring of blood glucose.

  11. Insect Biometrics: Optoacoustic Signal Processing and Its Applications to Remote Monitoring of McPhail Type Traps.

    Science.gov (United States)

    Potamitis, Ilyas; Rigakis, Iraklis; Fysarakis, Konstantinos

    2015-01-01

    Monitoring traps are important components of integrated pest management applied against important fruit fly pests, including Bactrocera oleae (Gmelin) and Ceratitis capitata (Widemann), Diptera of the Tephritidae family, which effect a crop-loss/per year calculated in billions of euros worldwide. Pests can be controlled with ground pesticide sprays, the efficiency of which depends on knowing the time, location and extent of infestations as early as possible. Trap inspection is currently carried out manually, using the McPhail trap, and the mass spraying is decided based on a decision protocol. We introduce the term 'insect biometrics' in the context of entomology as a measure of a characteristic of the insect (in our case, the spectrum of its wingbeat) that allows us to identify its species and make devices to help face old enemies with modern means. We modify a McPhail type trap into becoming electronic by installing an array of photoreceptors coupled to an infrared emitter, guarding the entrance of the trap. The beating wings of insects flying in the trap intercept the light and the light fluctuation is turned to a recording. Custom-made electronics are developed that are placed as an external add-on kit, without altering the internal space of the trap. Counts from the trap are transmitted using a mobile communication network. This trap introduces a new automated remote-monitoring method different to audio and vision-based systems. We evaluate our trap in large number of insects in the laboratory by enclosing the electronic trap in insectary cages. Our experiments assess the potential of delivering reliable data that can be used to initialize reliably the spraying process at large scales but to also monitor the impact of the spraying process as it eliminates the time-lag between acquiring and delivering insect counts to a central agency.

  12. Geiger Muller (GM) detector as online monitor: an experimental study

    International Nuclear Information System (INIS)

    Jayan, M.P.; Pawar, V.J.; Krishnakumar, P.; Sureshkumar, M.

    2014-01-01

    Monitoring the inadvertent release of radioactivity into otherwise inactive liquid streams is a common requirement in nuclear industry. In addition to conventional off-line sampling and measurement methods, nuclear facilities usually uses online methods to get real-time detection of activity contents in process cooling water lines and steam condensate lines. Due to its simplicity, ruggedness and cost effectiveness, Geiger Muller counter is obviously the first choice for online application. Though GM based monitors for such online application were in industrial use for a long time, practical data on the response of the detector with respect low level activities in the effluents is scarce in literature. This work was carried out to fill this information gap. The data generated in these experiments may be useful in giving a realistic interpretation of the response of the existing monitors and setting up their alarm limits

  13. Improving management and effectiveness of home blood pressure monitoring: a qualitative UK primary care study.

    Science.gov (United States)

    Grant, Sabrina; Greenfield, Sheila M; Nouwen, Arie; McManus, Richard J

    2015-11-01

    Self-monitoring blood pressure (SMBP) is becoming an increasingly prevalent practice in UK primary care, yet there remains little conceptual understanding of why patients with hypertension engage in self-monitoring. To identify psychological factors or processes prompting the decision to self-monitor blood pressure. A qualitative study of patients previously participating in a survey study about SMBP from four general practices in the West Midlands. Taped and transcribed in-depth interviews with 16 patients (6 currently monitoring, 2 used to self-monitor, and 8 had never self-monitored). Thematic analysis was undertaken. Three main themes emerged: 'self' and 'living with hypertension' described the emotional element of living with an asymptomatic condition; 'self-monitoring behaviour and medication' described overall views about self-monitoring, current practice, reasons for monitoring, and the impact on medication adherence; and 'the GP-patient transaction' described the power relations affecting decisions to self-monitor. Self-monitoring was performed by some as a protective tool against the fears of a silent but serious condition, whereas others self-monitor simply out of curiosity. People who self-monitored tended not to discuss this with their nurse or GP, partly due to perceiving minimal or no interest from their clinician about home monitoring, and partly due to fear of being prescribed additional medication. The decision to self-monitor appeared often to be an individual choice with no schedule or systems to integrate it with other medical care. Better recognition by clinicians that patients are self-monitoring, perhaps utilising the results in shared decision-making, might help integrate it into daily practice. © British Journal of General Practice 2015.

  14. A Study on Drug Safety Monitoring Program in India

    Science.gov (United States)

    Ahmad, A.; Patel, Isha; Sanyal, Sudeepa; Balkrishnan, R.; Mohanta, G. P.

    2014-01-01

    Pharmacovigilance is useful in assuring the safety of medicines and protecting the consumers from their harmful effects. A number of single drugs as well as fixed dose combinations have been banned from manufacturing, marketing and distribution in India. An important issue about the availability of banned drugs over the counter in India is that sufficient adverse drug reactions data about these drugs have not been reported. The most common categories of drugs withdrawn in the last decade were nonsteroidal antiinflammatory drugs (28%), antidiabetics (14.28%), antiobesity (14.28%), antihistamines (14.28%), gastroprokinetic drugs (7.14%), breast cancer and infertility drugs (7.14%), irritable bowel syndrome and constipation drugs (7.14%) and antibiotics (7.14%). Drug withdrawals from market were made mainly due to safety issues involving cardiovascular events (57.14%) and liver damage (14.28%). Majority of drugs have been banned since 3-5 years in other countries but are still available for sale in India. The present study compares the drug safety monitoring systems in the developed countries such as the USA and UK and provides implications for developing a system that can ensure the safety and efficacy of drugs in India. Absence of a gold standard for a drug safety surveillance system, variations in culture and clinical practice across countries makes it difficult for India to completely adopt another country's practices. There should be a multidisciplinary approach towards drug safety that should be implemented throughout the entire duration spanning from drug discovery to usage by consumers. PMID:25425751

  15. Monitoring early biofilm formation in cooling water systems using electrochemical probes made of AISI Type 316 stainless steel

    International Nuclear Information System (INIS)

    George, R.P.; Muraleedharan, P.; Dayal, R.K.; Khatak, H.S.

    2010-01-01

    Microorganisms in natural waters often adhere onto material surfaces in cooling water systems; they secrete slime, trap nutrients and reproduce, resulting in a complex biofilm that hampers the property of the condenser material. Biofilm formation on titanium material (commercial y pure, CP), used as condenser material, reduces heat-transfer efficiency. Experience worldwide has shown that routine water treatment programmes cannot remain effective under varying environmental, design and operation factors. Thus, the need of the hour is a means to continuously monitor the effectiveness of the control programmes and facilities to modify it as per need. In our laboratory we are involved in developing a probe based on electrochemical techniques to monitor early biofilm formation. Our earlier experience has shown that changes in some electrochemical parameters like open circuit potential (OCP) ennoblement, increase in passive current density and active repassivation potential would indicate crevice-stabilization tendencies of a heterogeneous biofilm on stainless steel materials. Literature further explains that there is a distinct time lag between crevice initiation and crevice propagation. Hence, it was hypothesized that if we can provide necessary conditions of crevice initiations artificially by intermittent polarization, electrochemical signals generated during crevice initiation can diagnose the causative agent of the crevice, that is, biofilm. However, care should be taken to avoid crevice propagation. Thus, attempts were made to distinguish the response of current to temporary application of a potential difference between two similar stainless steels (AISI Type 304, 316) and titanium electrodes in the biofilm forming environment. (author)

  16. Outward electron transfer by Saccharomyces cerevisiae monitored with a bi-cathodic microbial fuel cell-type activity sensor.

    Science.gov (United States)

    Ducommun, Raphaël; Favre, Marie-France; Carrard, Delphine; Fischer, Fabian

    2010-03-01

    A Janus head-like bi-cathodic microbial fuel cell was constructed to monitor the electron transfer from Saccharomyces cerevisiae to a woven carbon anode. The experiments were conducted during an ethanol cultivation of 170 g/l glucose in the presence and absence of yeast-peptone medium. First, using a basic fuel-cell type activity sensor, it was shown that yeast-peptone medium contains electroactive compounds. For this purpose, 1% solutions of soy peptone and yeast extract were subjected to oxidative conditions, using a microbial fuel cell set-up corresponding to a typical galvanic cell, consisting of culture medium in the anodic half-cell and 0.5 M K(3)Fe(CN)(6) in the cathodic half-cell. Second, using a bi-cathodic microbial fuel cell, it was shown that electrons were transferred from yeast cells to the carbon anode. The participation of electroactive compounds in the electron transport was separated as background current. This result was verified by applying medium-free conditions, where only glucose was fed, confirming that electrons are transferred from yeast cells to the woven carbon anode. Knowledge about the electron transfer through the cell membrane is of importance in amperometric online monitoring of yeast fermentations and for electricity production with microbial fuel cells. Copyright (c) 2009 John Wiley & Sons, Ltd.

  17. Remote Monitoring of Hypertension Diseases in Pregnancy: A Pilot Study.

    Science.gov (United States)

    Lanssens, Dorien; Vandenberk, Thijs; Smeets, Christophe Jp; De Cannière, Hélène; Molenberghs, Geert; Van Moerbeke, Anne; van den Hoogen, Anne; Robijns, Tiziana; Vonck, Sharona; Staelens, Anneleen; Storms, Valerie; Thijs, Inge M; Grieten, Lars; Gyselaers, Wilfried

    2017-03-09

    Although remote monitoring (RM) has proven its added value in various health care domains, little is known about the remote follow-up of pregnant women diagnosed with a gestational hypertensive disorders (GHD). The aim of this study was to evaluate the added value of a remote follow-up program for pregnant women diagnosed with GHD. A 1-year retrospective study was performed in the outpatient clinic of a 2nd level prenatal center where pregnant women with GHD received RM or conventional care (CC). Primary study endpoints include number of prenatal visits and admissions to the prenatal observation ward. Secondary outcomes include gestational outcome, mode of delivery, neonatal outcome, and admission to neonatal intensive care (NIC). Differences in continuous and categorical variables in maternal demographics and characteristics were tested using Unpaired Student's two sampled t test or Mann-Whitney U test and the chi-square test. Both a univariate and multivariate analysis were performed for analyzing prenatal follow-up and gestational outcomes. All statistical analyses were done at nominal level, Cronbach alpha=.05. Of the 166 patients diagnosed with GHD, 53 received RM and 113 CC. After excluding 5 patients in the RM group and 15 in the CC group because of the missing data, 48 patients in RM group and 98 in CC group were taken into final analysis. The RM group had more women diagnosed with gestational hypertension, but less with preeclampsia when compared with CC (81.25% vs 42.86% and 14.58% vs 43.87%). Compared with CC, univariate analysis in RM showed less induction, more spontaneous labors, and less maternal and neonatal hospitalizations (48.98% vs 25.00%; 31.63% vs 60.42%; 74.49% vs 56.25%; and 27.55% vs 10.42%). This was also true in multivariate analysis, except for hospitalizations. An RM follow-up of women with GHD is a promising tool in the prenatal care. It opens the perspectives to reverse the current evolution of antenatal interventions leading to more

  18. Fluid Status in Peritoneal Dialysis Patients: The European Body Composition Monitoring (EuroBCM) Study Cohort

    Science.gov (United States)

    Van Biesen, Wim; Williams, John D.; Covic, Adrian C.; Fan, Stanley; Claes, Kathleen; Lichodziejewska-Niemierko, Monika; Verger, Christian; Steiger, Jurg; Schoder, Volker; Wabel, Peter; Gauly, Adelheid; Himmele, Rainer

    2011-01-01

    Background Euvolemia is an important adequacy parameter in peritoneal dialysis (PD) patients. However, accurate tools to evaluate volume status in clinical practice and data on volume status in PD patients as compared to healthy population, and the associated factors, have not been available so far. Methods We used a bio-impedance spectroscopy device, the Body Composition Monitor (BCM) to assess volume status in a cross-sectional cohort of prevalent PD patients in different European countries. The results were compared to an age and gender matched healthy population. Results Only 40% out of 639 patients from 28 centres in 6 countries were normovolemic. Severe fluid overload was present in 25.2%. There was a wide scatter in the relation between blood pressure and volume status. In a multivariate analysis in the subgroup of patients from countries with unrestricted availability of all PD modalities and fluid types, older age, male gender, lower serum albumin, lower BMI, diabetes, higher systolic blood pressure, and use of at least one exchange per day with the highest hypertonic glucose were associated with higher relative tissue hydration. Neither urinary output nor ultrafiltration, PD fluid type or PD modality were retained in the model (total R2 of the model = 0.57). Conclusions The EuroBCM study demonstrates some interesting issues regarding volume status in PD. As in HD patients, hypervolemia is a frequent condition in PD patients and blood pressure can be a misleading clinical tool to evaluate volume status. To monitor fluid balance, not only fluid output but also dietary input should be considered. Close monitoring of volume status, a correct dialysis prescription adapted to the needs of the patient and dietary measures seem to be warranted to avoid hypervolemia. PMID:21390320

  19. A study of vitiligo in type 2 diabetic patients

    Directory of Open Access Journals (Sweden)

    Leena Raveendra

    2017-01-01

    Full Text Available Context: Diabetes mellitus is associated with many skin manifestations including vitiligo. Vitiligo occurs more commonly in Type 1 diabetes mellitus. A few recent studies have shown its increased occurrence in Type 2 diabetes mellitus. Aims: This study aims to study the prevalence of vitiligo in Type 2 diabetic patients and to compare the prevalence of vitiligo in age- and sex-matched group of nondiabetic population. Settings and Design: The present study was a hospital-based cross-sectional study conducted in the Department of Dermatology in a tertiary care hospital. Subjects and Methods: Six hundred consecutive consenting patients of Type 2 diabetes were included in the study group and age- and sex-matched controls were healthy nondiabetic adult volunteers attending the Department of Dermatology. Fasting and postprandial blood sugar levels were done. A complete history, physical examination, and wood's lamp examination to detect vitiligo were conducted. In all those with vitiligo, the type of vitiligo was noted. Statistical Analysis Used: Data were analyzed using SPSS software version 20.0. Comparison between the presence of vitiligo in cases and controls was done using Chi-square test with P = 0.05 for significance. Results: Vitiligo was seen in 12% of cases and 6% of control group which was statistically significant (P < 0.01. There was no significant difference between cases and controls with respect to type of vitiligo. Conclusions: Vitiligo can occur in Type 2 diabetics as seen in our study and few other recent studies. The exact pathogenesis is not very clear and needs further consideration.

  20. Effects of self-monitoring of glucose on distress and self-efficacy in people with non-insulin-treated Type 2 diabetes: a randomized controlled trial

    NARCIS (Netherlands)

    Malanda, U. L.; Bot, S. D. M.; Kostense, P. J.; Snoek, F. J.; Dekker, J. M.; Nijpels, G.

    2016-01-01

    To investigate the effects of self-monitoring of glucose in blood or urine, on diabetes-specific distress and self-efficacy, compared with usual care in people with non-insulin-treated Type 2 diabetes mellitus. One hundred and eighty-one participants with non-insulin-treated Type 2 diabetes mellitus

  1. Monitoring consumer confidence in food safety: an exploratory study

    NARCIS (Netherlands)

    Jonge, de J.; Frewer, L.J.; Trijp, van J.C.M.; Renes, R.J.; Wit, de W.; Timmers, J.C.M.

    2004-01-01

    Abstract: In response to the potential for negative economic and societal effects resulting from a low level of consumer confidence in food safety, it is important to know how confidence is potentially influenced by external events. The aim of this article is to describe the development of a monitor

  2. Monitoring Requirements Coverage Using Reconstructed Views : An Industrial Case Study

    NARCIS (Netherlands)

    Lormans, M.; Gross, H.; Van Deursen, A.; Van Solingen, R.; Stehouwer, A.

    2006-01-01

    Requirements views, such as coverage and status views, are an important asset for monitoring and managing software development. We have developed a method that automates the process for reconstructing these views, and built a tool, ReqAnalyst, to support this method. In this paper, we investigate to

  3. Study on a monitoring strategy to support decision making for geological repository closure

    International Nuclear Information System (INIS)

    Suyama, Yasuhiro; Tanabe, Hiromi; Eto, Jiro; Yoshimura, Kimitaka

    2010-01-01

    Japan currently plans to dispose of high-level radioactive wastes (vitrified HLWs) produced from the reprocessing of spent nuclear fuel in deep geological formations, in order to isolate the radioactive wastes from the human environment for tens of thousands of years. Such a geological repository must be designed to ensure operational safety and post-closure safety. Then, following the closure of the geological repository, post-closure safety will be provided by an engineered barrier system (EBS) and a natural barrier system (NBS) without relying on monitoring or institutional control. However, from a technical standpoint, monitoring has been required during backfilling in current studies. Additionally, there has been strong social pressure to continue monitoring during all the phases including post-closure. On the basis of the current situations, a monitoring strategy for geological disposal must be studied to ensure the long term safety of geological disposal. Focusing on decision making for geological repository closure, the authors have created a basic logical structure for the decision making process with the principles for ensuring safety and have developed a monitoring strategy based on the logical structure. The monitoring strategy is founded on three key aspects: the role of monitoring, boundary conditions of monitoring at the time of decision making, and a methodology for monitoring planning. Then, the monitoring strategy becomes a starting point of monitoring planning during site characterization, construction, operation and staged closure, as well as post-closure with institutional control, and of social science studies. (author)

  4. Effects of self-monitoring of glucose on distress and self-efficacy in people with non-insulin-treated Type 2 diabetes: a randomized controlled trial.

    Science.gov (United States)

    Malanda, U L; Bot, S D M; Kostense, P J; Snoek, F J; Dekker, J M; Nijpels, G

    2016-04-01

    To investigate the effects of self-monitoring of glucose in blood or urine, on diabetes-specific distress and self-efficacy, compared with usual care in people with non-insulin-treated Type 2 diabetes mellitus. One hundred and eighty-one participants with non-insulin-treated Type 2 diabetes mellitus [diabetes duration ≥ 1 year, age 45-75 years, HbA1c ≥ 53.0 mmol/mol (7.0%), self-monitoring frequency self-monitoring (n = 60), urine self-monitoring (n = 59) or usual care (n = 62). Primary outcomes were between-group differences in diabetes-specific distress [Problem Areas in Diabetes scale (PAID)] and self-efficacy [Confidence in Diabetes Self-Care questionnaire (CIDS-2)] after 12 months. Secondary outcomes included changes in HbA1c , treatment satisfaction and depressive symptoms. There were no statistically significant between-group differences in changes in PAID and CIDS-2 after 12 months. Mean difference in PAID between blood monitoring and control was -2.2 [95% confidence interval (CI) -7.1 to 2.7], between urine monitoring and control was -0.9 (95% CI -4.4 to 2.5) and between blood monitoring and urine monitoring was -2.0 (95% CI -4.1 to 0.1). Mean difference in CIDS-2 between blood monitoring and control was 0.6 [95% CI (-2.0 to 2.1), between urine monitoring and control was 2.8 (95% CI -2.3 to 7.9)] and between blood monitoring and urine monitoring was -3.3 (95% CI -7.9 to 1.3). No statistically significant between-group differences in change in any of the secondary outcome measures were found. This study did not find statistical or clinical evidence for a long-term effect of self-monitoring of glucose in blood or urine on diabetes-specific distress and self-efficacy in people with moderately controlled non-insulin-treated Type 2 diabetes mellitus. (Current Controlled Trials ISRCTN84568563). © 2015 Diabetes UK.

  5. Study of static properties of magnetron-type space charges

    International Nuclear Information System (INIS)

    Delcroix, Jean-Loup

    1953-01-01

    This research thesis reports an in-depth analysis of physical properties of static regimes to address the issue of space charges. This theoretical study of the Hull magnetron is followed by the description of experiments on the Hull magnetron which highlight transitions between the different regimes. Then, another theoretical approach aims at generalising the magnetron theory, based on other types of magnetron theory (general equations of magnetron-type space charges, inverted Hull magnetron theory, circular field magnetron theory)

  6. A 3-Month Randomized Controlled Pilot Trial of a Patient-Centered, Computer-Based Self-Monitoring System for the Care of Type 2 Diabetes Mellitus and Hypertension.

    Science.gov (United States)

    Or, Calvin; Tao, Da

    2016-04-01

    This study was performed to evaluate the effects of a patient-centered, tablet computer-based self-monitoring system for chronic disease care. A 3-month randomized controlled pilot trial was conducted to compare the use of a computer-based self-monitoring system in disease self-care (intervention group; n = 33) with a conventional self-monitoring method (control group; n = 30) in patients with type 2 diabetes mellitus and/or hypertension. The system was equipped with a 2-in-1 blood glucose and blood pressure monitor, a reminder feature, and video-based educational materials for the care of the two chronic diseases. The control patients were given only the 2-in-1 monitor for self-monitoring. The outcomes reported here included the glycated hemoglobin (HbA1c) level, fasting blood glucose level, systolic blood pressure, diastolic blood pressure, chronic disease knowledge, and frequency of self-monitoring. The data were collected at baseline and at 1-, 2-, and 3-month follow-up visits. The patients in the intervention group had a significant decrease in mean systolic blood pressure from baseline to 1 month (p computer-assisted and conventional disease self-monitoring appear to be useful to support/maintain blood pressure and diabetes control. The beneficial effects of the use of electronic self-care resources and support provided via mobile technologies require further confirmation in longer-term, larger trials.

  7. Effect of Continuous Glucose Monitoring Accuracy on Clinicians' Retrospective Decision Making in Diabetes: A Pilot Study

    DEFF Research Database (Denmark)

    Mahmoudi, Zeinab; Johansen, Mette Dencker; Nørgaard, Hanne Holdflod

    2015-01-01

    BACKGROUND: The use of continuous glucose monitoring (CGM) in clinical decision making in diabetes could be limited by the inaccuracy of CGM data when compared to plasma glucose measurements. The aim of the present study is to investigate the impact of CGM numerical accuracy on the precision...... of diabetes treatment adjustments. METHOD: CGM profiles with maximum 5-day duration from 12 patients with type 1 diabetes treated with a basal-bolus insulin regimen were processed by 2 CGM algorithms, with the accuracy of algorithm 2 being higher than the accuracy of algorithm 1, using the median absolute...... of the interclinician agreement and the intraclinician reproducibility of the decisions. The Cohen's kappa coefficient was used to assess the precision of the decisions. The study was based on retrospective and blind CGM data. RESULTS: For the interclinician agreement, in the first occasion, the kappa of algorithm 1...

  8. Acquired Cutis Laxa Type I: Laxity Treatment Efficacy by Non-Ablative Radiofrequency Monitoring by Cutometer

    Directory of Open Access Journals (Sweden)

    Nuntida Prasertworonun, M.D.

    2017-11-01

    Full Text Available Objective: To demonstrate the treatment efficicacy of tripolar radiofrequency (RF in a Thai middle-aged female with generalized acquired CL. Case presentation: The patient was treated by tripolar RF device at face and forehead at weeks 0, 2, and 3. The gross elasticity of the skin was measured pre and post treatment by cutometer and physician assessment. After two treatment sessions, the skin elasticity at the treatment area evaluated both by physician assessment and cutometer did not reveal significant improvement. The patient was lost to follow up after the third treatment session. Conclusion: Tripolar RF did not improve skin elasticity at week 3. Future studies are required to determine the physiological effect of RF in CL, appropriate tripolar RF parameters, timing, as well as developing the suitable method of measurement of the skin elasticity in CL.

  9. Self-monitoring of blood glucose versus self-monitoring of urine glucose in adults with newly diagnosed Type 2 diabetes receiving structured education: a cluster randomized controlled trial.

    Science.gov (United States)

    Dallosso, H M; Bodicoat, D H; Campbell, M; Carey, M E; Davies, M J; Eborall, H C; Hadjiconstantinou, M; Khunti, K; Speight, J; Heller, S

    2015-03-01

    To compare the effectiveness and acceptability of self-monitoring of blood glucose with self-monitoring of urine glucose in adults with newly diagnosed Type 2 diabetes. We conducted a multi-site cluster randomized controlled trial with practice-level randomization. Participants attended a structured group education programme, which included a module on self-monitoring using blood glucose or urine glucose monitoring. HbA1c and other biomedical measures as well as psychosocial data were collected at 6, 12 and 18 months. A total of 292 participants with Type 2 diabetes were recruited from 75 practices. HbA1c levels were significantly lower at 18 months than at baseline in both the blood monitoring group [mean (se) -12 (2) mmol/mol; -1.1 (0.2) %] and the urine monitoring group [mean (se) -13 (2) mmol/mol; -1.2 (0.2)%], with no difference between groups [mean difference adjusted for cluster effect and baseline value = -1 mmol/mol (95% CI -3, 2); -0.1% (95% CI -0.3, 0.2)]. Similar improvements were observed for the other biomedical outcomes, with no differences between groups. Both groups showed improvements in total treatment satisfaction, generic well-being, and diabetes-specific well-being, and had a less threatening view of diabetes, with no differences between groups at 18 months. Approximately one in five participants in the urine monitoring arm switched to blood monitoring, while those in the blood monitoring arm rarely switched (18 vs 1% at 18 months; P self-monitoring. © 2014 The Authors. Diabetic Medicine © 2014 Diabetes UK.

  10. DreamTel; Diabetes risk evaluation and management tele-monitoring study protocol.

    Science.gov (United States)

    Tobe, Sheldon W; Wentworth, Joan; Ironstand, Laurie; Hartman, Susan; Hoppe, Jackie; Whiting, Judi; Kennedy, Janice; McAllister, Colin; Kiss, Alex; Perkins, Nancy; Vincent, Lloyd; Pylypchuk, George; Lewanczuk, Richard Z

    2009-05-09

    The rising prevalence of type 2 diabetes underlines the importance of secondary strategies for the prevention of target organ damage. While access to diabetes education centers and diabetes intensification management has been shown to improve blood glucose control, these services are not available to all that require them, particularly in rural and northern areas. The provision of these services through the Home Care team is an advance that can overcome these barriers. Transfer of blood glucose data electronically from the home to the health care provider may improve diabetes management. The study population will consist of patients with type 2 diabetes with uncontrolled A1c levels living on reserve in the Battlefords region of Saskatchewan, Canada. This pilot study will take place over three phases. In the first phase over three months the impact of the introduction of the Bluetooth enabled glucose monitor will be assessed. In the second phase over three months, the development of guidelines based treatment algorithms for diabetes intensification will be completed. In the third phase lasting 18 months, study subjects will have diabetes intensification according to the algorithms developed. The first phase will determine if the use of the Bluetooth enabled blood glucose devices which can transmit results electronically will lead to changes in A1c levels. It will also determine the feasibility of recruiting subjects to use this technology. The rest of the Diabetes Risk Evaluation and Management Tele-monitoring (DreamTel) study will determine if the delivery of a diabetes intensification management program by the Home Care team supported by the Bluetooth enabled glucose meters leads to improvements in diabetes management. Protocol NCT00325624.

  11. Headache as an Aura of Epilepsy: Video-EEG Monitoring Study.

    Science.gov (United States)

    Kim, Dong Wook; Sunwoo, Jun-Sang; Lee, Sang Kun

    2016-04-01

    Headache can be associated with epilepsy as a pre-ictal, ictal, or post-ictal phenomenon; however, studies of patients with headache as an epileptic aura are scarce. We performed the present study to investigate the incidence and characteristics of headache as an epileptic aura, via confirmation of electroencephalography (EEG) changes by video-EEG monitoring. Data of aura and clinical seizure episodes of 831 consecutive patients who undertook video-EEG monitoring were analyzed retrospectively. For patients who had headache as an aura, information on the detailed features of headache was acquired, including location, nature, duration, and the presence of accompanying symptoms. Video-recorded clinical seizures, EEG findings, and neuroimaging data were used to determine the ictal onset areas in the patients. Six out of 831 (0.7%) patients experienced headache as aura (age range, 25-52 years), all of whom had partial seizures. The incidence of pre-ictal headache was 6.3% (25/831), and post-ictal headache was 30.9% (257/831). In patients with headache as aura, five patients described headache as the most frequent aura, and headache was the second most frequent aura in one patient. The characteristics of headache were hemicrania epileptica in two patients, tension-type headache in another two patients, and migraine-like headache in the remaining two patients. No patient met the diagnostic criteria of ictal epileptic headache or migraine aura-triggered seizure. Our study showed that headache as an aura is uncommon in adult patients with epilepsy, and that headache can present as diverse features, including hemicrania epileptica, tension-type headache, and migraine-like headache. Further studies are necessary to characterize the features of headache as an epileptic aura in adult patients with epilepsy. © 2016 American Headache Society.

  12. DreamTel; Diabetes risk evaluation and management tele-monitoring study protocol

    Directory of Open Access Journals (Sweden)

    Kiss Alex

    2009-05-01

    Full Text Available Abstract Background The rising prevalence of type 2 diabetes underlines the importance of secondary strategies for the prevention of target organ damage. While access to diabetes education centers and diabetes intensification management has been shown to improve blood glucose control, these services are not available to all that require them, particularly in rural and northern areas. The provision of these services through the Home Care team is an advance that can overcome these barriers. Transfer of blood glucose data electronically from the home to the health care provider may improve diabetes management. Methods and design The study population will consist of patients with type 2 diabetes with uncontrolled A1c levels living on reserve in the Battlefords region of Saskatchewan, Canada. This pilot study will take place over three phases. In the first phase over three months the impact of the introduction of the Bluetooth enabled glucose monitor will be assessed. In the second phase over three months, the development of guidelines based treatment algorithms for diabetes intensification will be completed. In the third phase lasting 18 months, study subjects will have diabetes intensification according to the algorithms developed. Discussion The first phase will determine if the use of the Bluetooth enabled blood glucose devices which can transmit results electronically will lead to changes in A1c levels. It will also determine the feasibility of recruiting subjects to use this technology. The rest of the Diabetes Risk Evaluation and Management Tele-monitoring (DreamTel study will determine if the delivery of a diabetes intensification management program by the Home Care team supported by the Bluetooth enabled glucose meters leads to improvements in diabetes management. Trial Registration Protocol NCT00325624

  13. Glycemic load, exercise, and monitoring blood glucose (GEM): A paradigm shift in the treatment of type 2 diabetes mellitus.

    Science.gov (United States)

    Cox, Daniel J; Taylor, Ann G; Singh, Harsimran; Moncrief, Matthew; Diamond, Anne; Yancy, William S; Hegde, Shefali; McCall, Anthony L

    2016-01-01

    This preliminary RCT investigated whether an integrated lifestyle modification program that focuses on reducing postprandial blood glucose through replacing high with low glycemic load foods and increasing routine physical activities guided by systematic self-monitoring of blood glucose (GEM) could improve metabolic control of adults with type 2 diabetes mellitus, without compromising other physiological parameters. Forty-seven adults (mean age 55.3 years) who were diagnosed with type 2 diabetes mellitus for less than 5 years (mean 2.1 years), had HbA1c ≥ 7% (mean 8.4%) and were not taking blood glucose lowering medications, were randomized to routine care or five 1-h instructional sessions of GEM. Assessments at baseline and 6 months included a physical exam, metabolic and lipid panels, and psychological questionnaires. The GEM intervention led to significant improvements in HbA1c (decreasing from 8.4 to 7.4% [69-57 mmol/mol] compared with 8.3 to 8.3% [68-68 mmol/mol] for routine care; Interaction ptype 2 diabetes mellitus. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  14. Relationship between fluctuations in glucose levels measured by continuous glucose monitoring and vascular endothelial dysfunction in type 2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Torimoto Keiichi

    2013-01-01

    Full Text Available Abstract Background Fluctuations in blood glucose level cause endothelial dysfunction and play a critical role in onset and/or progression of atherosclerosis. We hypothesized that fluctuation in blood glucose levels correlate with vascular endothelial dysfunction and that this relationship can be assessed using common bedside medical devices. Methods Fluctuations in blood glucose levels were measured over 24 hours by continuous glucose monitoring (CGM on admission day 2 in 57 patients with type 2 diabetes mellitus. The reactive hyperemia index (RHI, an index of vascular endothelial function, was measured using peripheral arterial tonometry (EndoPAT on admission day 3. Results The natural logarithmic-scaled RHI (L_RHI correlated with SD (r=−0.504; PPP=0.001 and percentage of time ≥200 mg/dl (r=−0.292; P=0.028. In 12 patients with hypoglycemia, L_RHI also correlated with the percentage of time at hypoglycemia (r=−0.589; P=0.044. L_RHI did not correlate with HbA1c or fasting plasma glucose levels. Furthermore, L_RHI did not correlate with LDL cholesterol, HDL cholesterol, and triglyceride levels or with systolic and diastolic blood pressures. Finally, multivariate analysis identified MAGE as the only significant determinant of L_RHI. Conclusions Fluctuations in blood glucose levels play a significant role in vascular endothelial dysfunction in type 2 diabetes. Trial registration UMIN000007581

  15. Research on RCP400-TB50 type reactor coolant pump shaft seal failure analysis and monitoring method

    International Nuclear Information System (INIS)

    Yuan Chaolian; Shen Yuxian; Wang Chuan; Du Pengcheng

    2014-01-01

    Mechanical seal is widely applied in mechanical devices of nuclear power plant. 3-stages mechanical seal applied in reactor coolant pump (abbreviate to RCP) is a kind of product with top technology and manufacture difficulty. As the only running machine in primary loop of nuclear power plant, RCP is designed with high security, reliability and perform ability. So performance of its key component, 3-stages mechanical seal, could directly decide whether units can operate safely and reliably. In this paper mechanical seal used in RCP400-TB50 type RCP which in designed and manufactured by Andritz AG is selected as a typical example of dynamic pressure type mechanical seal applied in second generation NPP. Its structure and working principle is expounded. Engineering fluid mechanics theory is used to establish the mathematical model using for analyzing status of mechanical seal and deducing the theoretical formula. Its correctness is verified by compare with the test data. So that research result can be used as the theoretical basis for analysis of RCP400-TB50 RCP shaft seal's working condition. According to the shaft seal operation characteristic we can establish a suitable RCP shaft seal monitoring method and interlock protection setting for NPP operation. (authors)

  16. Feedback from physical activity monitors is not compatible with current recommendations: A recalibration study.

    Science.gov (United States)

    Thompson, Dylan; Batterham, Alan M; Peacock, Oliver J; Western, Max J; Booso, Rahuman

    2016-10-01

    Wearable devices to self-monitor physical activity have become popular with individuals and healthcare practitioners as a route to the prevention of chronic disease. It is not currently possible to reconcile feedback from these devices with activity recommendations because the guidelines refer to the amount of activity required on top of normal lifestyle activities (e.g., 150 minutes of moderate-to-vigorous intensity activity per week over-and-above normal moderate-to-vigorous lifestyle activities). The aim of this study was to recalibrate the feedback from self-monitoring. We pooled data from four studies conducted between 2006 and 2014 in patients and volunteers from the community that included both sophisticated measures of physical activity and 10-year risk for cardiovascular disease and type 2 diabetes (n=305). We determined the amount of moderate-to-vigorous intensity activity that corresponded to FAO/WHO/UNU guidance for a required PAL of 1.75 (Total Energy Expenditure/Basal Metabolic Rate). Our results show that, at the UK median PAL, total moderate-to-vigorous intensity physical activity will be around 735 minutes per week (~11% of waking time). We estimate that a 4% increase in moderate-to-vigorous intensity activity will achieve standardised guidance from FAO/WHO/UNU and will require ~1000 minutes of moderate-to-vigorous intensity activity per week. This study demonstrates that feedback from sophisticated wearable devices is incompatible with current physical activity recommendations. Without adjustment, people will erroneously form the view that they are exceeding recommendations by several fold. A more appropriate target from self-monitoring that accounts for normal moderate-to-vigorous lifestyle activities is ~1000 minutes per week, which represents ~15% of waking time. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  17. WRITING VERSUS TYPING DURING SCIENCE TEACHING: CASE STUDY IN SLOVENIA

    Directory of Open Access Journals (Sweden)

    Metka Kordigel Aberšek

    2018-02-01

    Full Text Available In a case study conducted in a biology class in Slovenia, six grade students participated in a biology project Writing Versus Typing in a Biology Class. The final task in this project was to write a chapter for a biology textbook with the title Urtica dioica. The task was performed twice: firstly, the text was written by the hand and secondly it was typed on the computer keyboard. Handwritten and keyboard typed scientific texts, textbook chapters, were compared with the special focus on the lexical, syntactic, and semantic level of the text. The purpose of this research was to find out the effect of replacing handwriting with typing in the process of teaching/learning science subjects, where the understanding of texts is of crucial importance. A closer look at the students’ text products in the typing modality reveals that students, while typing, seem to be cognitively overloaded. One of the consequences of this is a lower level of cognitive achievement in their typed text: students show less knowledge, less terminological accuracy, and, above all, a lesser understanding of the interconnection between the items of information provided.

  18. Noninvasive pulmonary artery pressure monitoring by EIT: a model-based feasibility study.

    Science.gov (United States)

    Proença, Martin; Braun, Fabian; Solà, Josep; Thiran, Jean-Philippe; Lemay, Mathieu

    2017-06-01

    Current monitoring modalities for patients with pulmonary hypertension (PH) are limited to invasive solutions. A novel approach for the noninvasive and unsupervised monitoring of pulmonary artery pressure (PAP) in patients with PH was proposed and investigated. The approach was based on the use of electrical impedance tomography (EIT), a noninvasive and safe monitoring technique, and was tested through simulations on a realistic 4D bio-impedance model of the human thorax. Changes in PAP were induced in the model by simulating multiple types of hypertensive conditions. A timing parameter physiologically linked to the PAP via the so-called pulse wave velocity principle was automatically estimated from the EIT data. It was found that changes in PAP could indeed be reliably monitored by EIT, irrespective of the pathophysiological condition that caused them. If confirmed clinically, these findings could open the way for a new generation of noninvasive PAP monitoring solutions for the follow-up of patients with PH.

  19. Leak detection, monitoring, and mitigation technology trade study update

    International Nuclear Information System (INIS)

    HERTZEL, J.S.

    1998-01-01

    This document is a revision and update to the initial report that describes various leak detection, monitoring, and mitigation (LDMM) technologies that can be used to support the retrieval of waste from the single-shell tanks (SST) at the Hanford Site. This revision focuses on the improvements in the technical performance of previously identified and useful technologies, and it introduces new technologies that might prove to be useful

  20. Satellite monitoring of remote volcanoes improves study efforts in Alaska

    Science.gov (United States)

    Dean, K.; Servilla, M.; Roach, A.; Foster, B.; Engle, K.

    Satellite monitoring of remote volcanoes is greatly benefitting the Alaska Volcano Observatory (AVO), and last year's eruption of the Okmok Volcano in the Aleutian Islands is a good case in point. The facility was able to issue and refine warnings of the eruption and related activity quickly, something that could not have been done using conventional seismic surveillance techniques, since seismometers have not been installed at these locations.AVO monitors about 100 active volcanoes in the North Pacific (NOPAC) region, but only a handful are observed by costly and logistically complex conventional means. The region is remote and vast, about 5000 × 2500 km, extending from Alaska west to the Kamchatka Peninsula in Russia (Figure 1). Warnings are transmitted to local communities and airlines that might be endangered by eruptions. More than 70,000 passenger and cargo flights fly over the region annually, and airborne volcanic ash is a threat to them. Many remote eruptions have been detected shortly after the initial magmatic activity using satellite data, and eruption clouds have been tracked across air traffic routes. Within minutes after eruptions are detected, information is relayed to government agencies, private companies, and the general public using telephone, fax, and e-mail. Monitoring of volcanoes using satellite image data involves direct reception, real-time monitoring, and data analysis. Two satellite data receiving stations, located at the Geophysical Institute, University of Alaska Fairbanks (UAF), are capable of receiving data from the advanced very high resolution radiometer (AVHRR) on National Oceanic and Atmospheric Administration (NOAA) polar orbiting satellites and from synthetic aperture radar (SAR) equipped satellites.

  1. Leak detection, monitoring, and mitigation technology trade study update

    Energy Technology Data Exchange (ETDEWEB)

    HERTZEL, J.S.

    1998-11-10

    This document is a revision and update to the initial report that describes various leak detection, monitoring, and mitigation (LDMM) technologies that can be used to support the retrieval of waste from the single-shell tanks (SST) at the Hanford Site. This revision focuses on the improvements in the technical performance of previously identified and useful technologies, and it introduces new technologies that might prove to be useful.

  2. Reference values for generic instruments used in routine outcome monitoring: the leiden routine outcome monitoring study

    Directory of Open Access Journals (Sweden)

    Schulte-van Maaren Yvonne WM

    2012-11-01

    Full Text Available Abstract Introduction The Brief Symptom Inventory (BSI, Mood & Anxiety Symptom Questionnaire −30 (MASQ-D30, Short Form Health Survey 36 (SF-36, and Dimensional Assessment of Personality Pathology-Short Form (DAPP-SF are generic instruments that can be used in Routine Outcome Monitoring (ROM of patients with common mental disorders. We aimed to generate reference values usually encountered in 'healthy' and ‘psychiatrically ill’ populations to facilitate correct interpretation of ROM results. Methods We included the following specific reference populations: 1294 subjects from the general population (ROM reference group recruited through general practitioners, and 5269 psychiatric outpatients diagnosed with mood, anxiety, or somatoform (MAS disorders (ROM patient group. The outermost 5% of observations were used to define limits for one-sided reference intervals (95th percentiles for BSI, MASQ-D30 and DAPP-SF, and 5th percentiles for SF-36 subscales. Internal consistency and Receiver Operating Characteristics (ROC analyses were performed. Results Mean age for the ROM reference group was 40.3 years (SD=12.6 and 37.7 years (SD=12.0 for the ROM patient group. The proportion of females was 62.8% and 64.6%, respectively. The mean for cut-off values of healthy individuals was 0.82 for the BSI subscales, 23 for the three MASQ-D30 subscales, 45 for the SF-36 subscales, and 3.1 for the DAPP-SF subscales. Discriminative power of the BSI, MASQ-D30 and SF-36 was good, but it was poor for the DAPP-SF. For all instruments, the internal consistency of the subscales ranged from adequate to excellent. Discussion and conclusion Reference values for the clinical interpretation were provided for the BSI, MASQ-D30, SF-36, and DAPP-SF. Clinical information aided by ROM data may represent the best means to appraise the clinical state of psychiatric outpatients.

  3. Studies on radioactivity monitoring proceedure for marine organisms

    International Nuclear Information System (INIS)

    Koyanagi, Taku; Hirano, Shigeki

    1978-01-01

    Suitability of several species of mollusca and seaweeds as indicator organisms for radioactivity monitoring of marine environment was examined by radioisotope tracer experiments or stable elements analyses from the standpoints of the affinities for radionuclides, the sampling procedures, and the distribution of radioactive and stable elements in the body of these organisms. Extremely high concentration factor of 54 Mn was shown by kidney of scallop suggesting the suitability for the efficient monitoring of the nuclide though the contribution of kidney to the weight of scallop was very small. Higher concentration of 54 Mn in midgut gland rather than kidney was observed in the case of other species of shellfishes but distribution of the nuclide among organs or tissues of the organisms varied during the period of intake and excretion. Ununiform distribution of radioactive and stable elements among the species of seaweeds and in the body of seaweeds observed by the tracer experiments and stable element analyses suggested the necessity of careful selection of the samples for monitoring of these nuclides. From the results of tracer experiments carried out in order to elucidate the relation between existing state of radionuclides in seawater and uptake by marine organisms, it was supposed that the complexed forms with inorganic or organic ligands in seawater were predominant species of radioactive cerium in seawater. (author)

  4. Pennsylvania seismic monitoring network and related tectonic studies

    International Nuclear Information System (INIS)

    Alexander, S.S.

    1991-06-01

    This report summarizes the results of the operation of the Pennsylvania Seismic Monitoring Network during the interval May 1, 1983--March 31, 1985 to monitor seismic activity in Pennsylvania and surrounding areas, to characterize the earthquake activity in terms of controlling tectonic structures and related tectonic stress conditions in the crust, and to obtain improved crustal velocity models for hypocentral determinations. Most of the earthquake activity was concentrated in the Lancaster, PA area. The magnitude 4.2 mainshock that occurred there on April 23, 1984 was the largest ever recorded instrumentally and its intensity of VI places it among the largest in the historic record for that area. Other activity during the monitoring interval of this report was confined to eastern Pennsylvania. The very large number of quarry explosions that occur regularly in Pennsylvania account for most of the seismic events recorded and they provide important crustal velocity data that are needed to obtain accurate hypocenter estimates. In general the earthquakes that occurred are located in areas of past historic seismicity. Block-tectonic structures resulting from pre-Ordovician tectonic displacements appear to influence the distribution of contemporary seismicity in Pennsylvania and surrounding areas. 17 refs., 5 figs

  5. Optimal river monitoring network using optimal partition analysis: a case study of Hun River, Northeast China.

    Science.gov (United States)

    Wang, Hui; Liu, Chunyue; Rong, Luge; Wang, Xiaoxu; Sun, Lina; Luo, Qing; Wu, Hao

    2018-01-09

    River monitoring networks play an important role in water environmental management and assessment, and it is critical to develop an appropriate method to optimize the monitoring network. In this study, an effective method was proposed based on the attainment rate of National Grade III water quality, optimal partition analysis and Euclidean distance, and Hun River was taken as a method validation case. There were 7 sampling sites in the monitoring network of the Hun River, and 17 monitoring items were analyzed once a month during January 2009 to December 2010. The results showed that the main monitoring items in the surface water of Hun River were ammonia nitrogen (NH 4 + -N), chemical oxygen demand, and biochemical oxygen demand. After optimization, the required number of monitoring sites was reduced from seven to three, and 57% of the cost was saved. In addition, there were no significant differences between non-optimized and optimized monitoring networks, and the optimized monitoring networks could correctly represent the original monitoring network. The duplicate setting degree of monitoring sites decreased after optimization, and the rationality of the monitoring network was improved. Therefore, the optimal method was identified as feasible, efficient, and economic.

  6. Validation of MODIS and SEVIRI Active Fire Monitoring products over Western Romania. Case study: Arad County

    Science.gov (United States)

    Oanea, Lavinia; Alina Ristea, Mihaela

    2014-05-01

    At the national level, the issue of wildfire monitoring represents a long debated topic. However, in the present situation, fire management requires various improvements in terms of detection, monitoring and post-fire analysis. The objectives of this study are to validate the data provided by MODIS (Terra and Aqua) Active Fire Monitoring and SEVIRI (MSG) FIR (Active Fire Monitoring) satellite products, with wildfires field data from The Romanian General Inspectorate for Emergency Situations (IGSU) (1), to chart the efficiency of satellite products in locating fires and study their strengths and weaknesses using a SWOT analysis (2). This is the initial step of a larger project that aims to implement an online Geographic Information System for fire management that will ease wildfire data manipulation and facilitate the decision making process. In order to do so, the current study objectives must be achieved. Our general strategy is to determine the consistency of direct (field measurements) and indirect (satellite data) observations. Depending on the amount of field information, the fire characteristics (location, frequency, extension area, moment of occurrence, type of fire, and others) will be studied through a statistical analysis. The products show some peculiar restrictiveness like spatial and temporal resolution. Specifically, we will process and interpret satellite products to identify wildfires according to the data from IGSU using specialized software. The case study for the application of these procedures is a set of fire events from Arad county - Romania, that occurred between 2007 and 2013. In order to do so, it is important to compare results from different sensors with field information through various methods and to use only consistent results. The results will play an important role in achieving the above mentioned informational system, which will integrate field information, satellite data and values of parameters that influence the evolution of

  7. Continuous monitoring of back wall stress corrosion cracking growth in sensitized type 304 stainless steel weldment by means of potential drop techniques

    OpenAIRE

    SATO, Y; ATSUMI, T; SHOJI, T

    2007-01-01

    Stress corrosion cracking (SCC) tests on welded specimens of sensitized type 304SS with a thickness of 20 mm were performed in sodium thiosulphate solution at room temperature, with continuous monitoring of the SCC growth, using the techniques of modified induced current potential drop (MICPD), alternating current potential drop (ACPD) and direct current potential drop (DCPD). The MICPD and DCPD techniques permit continuous monitoring of the back wall SCC, which initiates from a fatigue pre-c...

  8. Hadron-therapy beam monitoring: Towards a new generation of ultra-thin p-type silicon strip detectors

    International Nuclear Information System (INIS)

    Bouterfa, M.; Aouadi, K.; Bertrand, D.; Olbrechts, B.; Delamare, R.; Raskin, J. P.; Gil, E. C.; Flandre, D.

    2011-01-01

    Hadron-therapy has gained increasing interest for cancer treatment especially within the last decade. System commissioning and quality assurance procedures impose to monitor the particle beam using 2D dose measurements. Nowadays, several monitoring systems exist for hadron-therapy but all show a relatively high influence on the beam properties: indeed, most devices consist of several layers of materials that degrade the beam through scattering and energy losses. For precise treatment purposes, ultra-thin silicon strip detectors are investigated in order to reduce this beam scattering. We assess the beam size increase provoked by the Multiple Coulomb Scattering when passing through Si, to derive a target thickness. Monte-Carlo based simulations show a characteristic scattering opening angle lower than 1 mrad for thicknesses below 20 μm. We then evaluated the fabrication process feasibility. We successfully thinned down silicon wafers to thicknesses lower than 10 μm over areas of several cm 2 . Strip detectors are presently being processed and they will tentatively be thinned down to 20 μm. Moreover, two-dimensional TCAD simulations were carried out to investigate the beam detector performances on p-type Si substrates. Additionally, thick and thin substrates have been compared thanks to electrical simulations. Reducing the pitch between the strips increases breakdown voltage, whereas leakage current is quite insensitive to strips geometrical configuration. The samples are to be characterized as soon as possible in one of the IBA hadron-therapy facilities. For hadron-therapy, this would represent a considerable step forward in terms of treatment precision. (authors)

  9. Comparison of Trap Types, Placement, and Colors for Monitoring Anthonomus musculus (Coleoptera: Curculionidae) Adults in Highbush Blueberries

    Science.gov (United States)

    Silva, Diego; Salamanca, Jordano; Kyryczenko-Roth, Vera; Alborn, Hans T; Rodriguez-Saona, Cesar

    2018-01-01

    Abstract The cranberry weevil, Anthonomus musculus Say (Coleoptera: Curculionidae), is a key (univoltine) pest of highbush blueberries in the northeast United States. To date, however, no trapping system has been developed to successfully monitor this pest. In 2012–2014, studies were conducted in commercial highbush blueberry farms in New Jersey to 1) evaluate the efficacy of various commercially available traps, designed for other weevil species (e.g., pepper weevil, plum curculio, boll weevil, red palm weevil, and black vine weevil), in capturing A. musculus adults; 2) test whether the relative location of traps within the blueberry canopy affects adult captures and 3) determine the effects of different colored (yellow, white, green, red, blue, brown, and black) sticky traps on weevil captures. For a comparison with existing techniques, we also monitored the number of overwintered adult weevils on blueberry bushes using beat sheet sampling. Of all traps and colors tested, the most A. musculus adults were caught on yellow sticky traps and more adults were captured when these traps were placed at the bottom half of the blueberry canopy, i.e., 0.5–1.0 m above ground. Most weevils were caught on colored traps late in the season (i.e., during bloom), which corresponds mostly to the second (summer) adult generation. Thus, number of overwintered adults caught on traps did not correlate with those on bushes. Although our study identified traps that can be used to capture A. musculus adults, these traps alone (i.e., without semiochemicals) have so far limited applicability for monitoring overwintered adult weevils in highbush blueberries.

  10. Dual vs. single computer monitor in a Canadian hospital Archiving Department: a study of efficiency and satisfaction.

    Science.gov (United States)

    Poder, Thomas G; Godbout, Sylvie T; Bellemare, Christian

    This paper describes a comparative study of clinical coding by Archivists (also known as Clinical Coders in some other countries) using single and dual computer monitors. In the present context, processing a record corresponds to checking the available information; searching for the missing physician information; and finally, performing clinical coding. We collected data for each Archivist during her use of the single monitor for 40 hours and during her use of the dual monitor for 20 hours. During the experimental periods, Archivists did not perform other related duties, so we were able to measure the real-time processing of records. To control for the type of records and their impact on the process time required, we categorised the cases as major or minor, based on whether acute care or day surgery was involved. Overall results show that 1,234 records were processed using a single monitor and 647 records using a dual monitor. The time required to process a record was significantly higher (p= .071) with a single monitor compared to a dual monitor (19.83 vs.18.73 minutes). However, the percentage of major cases was significantly higher (p= .000) in the single monitor group compared to the dual monitor group (78% vs. 69%). As a consequence, we adjusted our results, which reduced the difference in time required to process a record between the two systems from 1.1 to 0.61 minutes. Thus, the net real-time difference was only 37 seconds in favour of the dual monitor system. Extrapolated over a 5-year period, this would represent a time savings of 3.1% and generate a net cost savings of $7,729 CAD (Canadian dollars) for each workstation that devoted 35 hours per week to the processing of records. Finally, satisfaction questionnaire responses indicated a high level of satisfaction and support for the dual-monitor system. The implementation of a dual-monitor system in a hospital archiving department is an efficient option in the context of scarce human resources and has the

  11. Reflection in Learning through a Self-monitoring Device: Design Research on EEG Self-Monitoring during a Study Session

    Directory of Open Access Journals (Sweden)

    Eva Durall

    2017-04-01

    Full Text Available The increasing availability of self-monitoring technologies has created opportunities for gaining awareness about one’s own behavior and reflecting on it. In teaching and learning, there is interest in using self-monitoring technologies, but very few studies have explored the possibilities. In this paper, we present a design study that investigates a technology (called Feeler that guides students to follow a specific learning script, monitors changes in their electroencephalogram (EEG while studying, and later provides visualization of the EEG data. The results are two-fold: (1 the hardware/software prototype and (2 the conclusions from the proof-of-concept research conducted with the prototype and six participants. In the research, we collected qualitative data from interviews to identify whether the prototype supported students to develop their reflective skills. The thematic analysis of the interviews showed that the Feeler’s learning script and visualization of the EEG data supported greater levels of reflection by fostering students’ curiosity, puzzlement, and personal inquiry. The proof-of-concept research also provided insights into several factors, such as the value of personal experience, the challenge of assumptions, and the contextualization of the data that trigger reflective thinking. The results validate the design concept and the role of the prototype in supporting awareness of and reflection about students’ mental states when they perform academic tasks.

  12. Study of fatigue, depression, and associated factors in type 2 diabetes mellitus in industrial workers

    Directory of Open Access Journals (Sweden)

    Akhilesh Jain

    2015-01-01

    Full Text Available Introduction: Type 2 diabetes mellitus is a significant health problem and imposes great physical, financial and psychological burden among the affected population. Among people with diabetes, fatigue is a pervasive and distressing complaint, which is further accentuated by presence of depression. Objective: To assess the prevalence of fatigue and depression and associated clinical and socio demographic correlates in type 2diabetes. Materials and Methods: This cross sectional study included 100 patients of diabetes type 2 and equal number of healthy controls between the ages of 18 to 70 years . A detailed evaluation of socio demographic and clinical parameters was made. Participants were also assessed for presence of depression and fatigue using PHQ-9 and Fatigue Severity Scale(FSSrespectively. Results: Fatigue and depression was found in 68 % and 53 % of diabetic participants. Diabetic patients were 10.37 times and 4.80 times more likely to suffer from fatigue and depression respectively. Both fatigue and depression were found to be significantly associated with duration of illness, fasting and post prandial blood glucose level ,diabetic complications and Body Mass Index (BMI. Fatigue was also strongly correlated with depression in study sample. Conclusions: Fatigue and depression are reasonably correlated with type 2 diabetes. Various clinical parameters of diabetes are strongly associated with both fatigue and depression. Fatigue itself has significant correlation with depression in type 2 diabetes. Regular monitoring of biochemical parameters are paramount to predict the development of fatigue and depression in type 2 diabetes.

  13. Pressurized water reactor monitoring. Study of detection, diagnostic and estimation methods (least error squares and filtering)

    International Nuclear Information System (INIS)

    Gillet, M.

    1986-07-01

    This thesis presents a study for the surveillance of the ''primary coolant circuit inventory monitoring'' of a pressurized water reactor. A reference model is developed in view of an automatic system ensuring detection and diagnostic in real time. The methods used for the present application are statistical tests and a method related to pattern recognition. The estimation of failures detected, difficult owing to the non-linearity of the problem, is treated by the least error squares method of the predictor or corrector type, and by filtering. It is in this frame that a new optimized method with superlinear convergence is developed, and that a segmented linearization of the model is introduced, in view of a multiple filtering [fr

  14. Measurement of outdoor radioactivities of radon and thoron by the passive radon-thoron monitor of cup type with cellulose nitrate film

    International Nuclear Information System (INIS)

    Ogawa, Y.; Kimura, Y.; Iida, T.; Yamasaki, K.; Tsujimoto, T.

    1993-01-01

    In order to get information as to effective dose of radon and thoron for the public, we investigated the dosimetry of the average outdoor concentrations of radon and thoron by the cup type radon/thoron monitor using cellulose nitrate film. To overcome the disadvantages of cup monitors which are the relatively low sensitivity and the relatively high detection limit, the present dosimetry is based on the usage of several pairs of cup monitors and the statistical treatments (significant test). Because the detection limit could be lowered using the present dosimetry, we could measure the outdoor concentration levels more precisely. (1 tab.)

  15. Study of thorium internal monitoring program by radiotoxicological analysis

    International Nuclear Information System (INIS)

    Gaburo, J.; Sordi, G.-M.A.A.

    1986-01-01

    The aim of this work is the establishment of a bioassay routine monitoring program for thorium occupationally exposed personnel. A simple and economic method for the analytical determination of the concentration of Th-232 in excreta samples was adopted, using Th-229 as a tracer. The mean yield of the method was 80%. Thorium concentration in excreta samples of non occupationally exposed Rio de Janeiro and Sao Paulo inhabitants was compared with data provenient from Nuclemon workers, with a exposition history to the nuclide of more than ten years and from IPEN workers only recently occupationally exposed to the nuclide. (Author) [pt

  16. Monitoring safety and use of old and new treatment options for type 2 diabetic patients: a two-year (2013-2016) analysis.

    Science.gov (United States)

    Leporini, Christian; Piro, Rosanna; Ursini, Francesco; Maida, Francesca; Palleria, Caterina; Arturi, Franco; Pavia, Maria; De Sarro, Giovambattista; Russo, Emilio

    2016-12-01

    To compare patients' and physicians' perceptions regarding effectiveness and tolerability of non-insulin hypoglycemic drugs in a cohort of type 2 diabetic patients; to verify whether a possible tridimensional link between effectiveness, tolerability, and adherence affects long-term therapeutic outcomes. A two-year observational study was performed in 1389 Type 2 diabetic patients by involving general practitioner clinics and Diabetes Centers. A decimal scale and the Morisky questionnaire were used, respectively, to assess effectiveness and tolerability perceptions, and medication adherence. Physicians perceived therapy as more efficacious compared to their patients: perceived effectiveness was steady for physicians during the study whereas patients' perception not significantly decreased (mean score from >8 to 7.84 ± 1.69). Physicians assigned higher tolerability scores compared to patients but only at the beginning of the study; interestingly, physicians' tolerability perception was poorer than patients' perception at last follow-up (mean score = 7.57 ± 1.40 vs. 7.88 ± 1.84). Favorable (score >7) patients' perceptions about treatment effectiveness and tolerability were associated with higher adherence. Patients showed medium adherence across the study. A mutual relationship between clinical effectiveness, adverse drug reactions, and adherence has been established, significantly impacting the clinical management of diabetic patients. A careful monitoring of this link by clinicians appears therefore necessary.

  17. SNP-based typing: a useful tool to study Bordetella pertussis populations.

    Directory of Open Access Journals (Sweden)

    Marjolein van Gent

    Full Text Available To monitor changes in Bordetella pertussis populations, mainly two typing methods are used; Pulsed-Field Gel Electrophoresis (PFGE and Multiple-Locus Variable-Number Tandem Repeat Analysis (MLVA. In this study, a single nucleotide polymorphism (SNP typing method, based on 87 SNPs, was developed and compared with PFGE and MLVA. The discriminatory indices of SNP typing, PFGE and MLVA were found to be 0.85, 0.95 and 0.83, respectively. Phylogenetic analysis, using SNP typing as Gold Standard, revealed false homoplasies in the PFGE and MLVA trees. Further, in contrast to the SNP-based tree, the PFGE- and MLVA-based trees did not reveal a positive correlation between root-to-tip distance and the isolation year of strains. Thus PFGE and MLVA do not allow an estimation of the relative age of the selected strains. In conclusion, SNP typing was found to be phylogenetically more informative than PFGE and more discriminative than MLVA. Further, in contrast to PFGE, it is readily standardized allowing interlaboratory comparisons. We applied SNP typing to study strains with a novel allele for the pertussis toxin promoter, ptxP3, which have a worldwide distribution and which have replaced the resident ptxP1 strains in the last 20 years. Previously, we showed that ptxP3 strains showed increased pertussis toxin expression and that their emergence was associated with increased notification in The Netherlands. SNP typing showed that the ptxP3 strains isolated in the Americas, Asia, Australia and Europe formed a monophyletic branch which recently diverged from ptxP1 strains. Two predominant ptxP3 SNP types were identified which spread worldwide. The widespread use of SNP typing will enhance our understanding of the evolution and global epidemiology of B. pertussis.

  18. SNP-Based Typing: A Useful Tool to Study Bordetella pertussis Populations

    Science.gov (United States)

    van der Heide, Han G. J.; Heuvelman, Kees J.; Kallonen, Teemu; He, Qiushui; Mertsola, Jussi; Advani, Abdolreza; Hallander, Hans O.; Janssens, Koen; Hermans, Peter W.; Mooi, Frits R.

    2011-01-01

    To monitor changes in Bordetella pertussis populations, mainly two typing methods are used; Pulsed-Field Gel Electrophoresis (PFGE) and Multiple-Locus Variable-Number Tandem Repeat Analysis (MLVA). In this study, a single nucleotide polymorphism (SNP) typing method, based on 87 SNPs, was developed and compared with PFGE and MLVA. The discriminatory indices of SNP typing, PFGE and MLVA were found to be 0.85, 0.95 and 0.83, respectively. Phylogenetic analysis, using SNP typing as Gold Standard, revealed false homoplasies in the PFGE and MLVA trees. Further, in contrast to the SNP-based tree, the PFGE- and MLVA-based trees did not reveal a positive correlation between root-to-tip distance and the isolation year of strains. Thus PFGE and MLVA do not allow an estimation of the relative age of the selected strains. In conclusion, SNP typing was found to be phylogenetically more informative than PFGE and more discriminative than MLVA. Further, in contrast to PFGE, it is readily standardized allowing interlaboratory comparisons. We applied SNP typing to study strains with a novel allele for the pertussis toxin promoter, ptxP3, which have a worldwide distribution and which have replaced the resident ptxP1 strains in the last 20 years. Previously, we showed that ptxP3 strains showed increased pertussis toxin expression and that their emergence was associated with increased notification in the Netherlands. SNP typing showed that the ptxP3 strains isolated in the Americas, Asia, Australia and Europe formed a monophyletic branch which recently diverged from ptxP1 strains. Two predominant ptxP3 SNP types were identified which spread worldwide. The widespread use of SNP typing will enhance our understanding of the evolution and global epidemiology of B. pertussis. PMID:21647370

  19. Brent coal typing by combined optical and geochemical studies

    Energy Technology Data Exchange (ETDEWEB)

    Ducazeaux, J.; Le Tran, K.; Nicolas, G. (Societe Nationale des Petroles d' Aquitaine (SNPA), 64 - Pau (France))

    1991-12-01

    Palynological,petrographical and organic geochemical studies show that various kinds of coal occur throughout the Middle Jurassic Brent Group in the Viking Graben. Two types of coal with strong contrast in terms of source rock potential are thoroughly investigated in this study. It is found that they are relevant to two distinct organic facies. Though having the same organic carbon content, they are very different with respect to the petroleum generating potential, one being a conventional gas-prone coal of type III kerogen and the other one of type II-(III) kerogen which should be considered as an oil-generating coal. Explanations are sought for the difference observed, both geochemically and optically. Palynological study shows the occurrence of two distinct communities of land plants in relation with the depositional environment and climatic changes, whilst coal petrographical study shows that the macerals are unevenly and differently distributed in these two coal types. The original organic material and the depositional environment appear to be the main controlling factors. 13 Refs.; 8 Figs.

  20. Some neutronic studies on flux-trap type moderator

    International Nuclear Information System (INIS)

    Kiyanagi, Y.; Watanabe, N.

    1991-01-01

    The neutronic performance of a flux-trap type moderator was studied by computer simulation in connection with the KENS-II target-moderator system. It was confirmed that this system can provide 1.3-1.4 times higher neutron intensity than a traditional wing-geometry moderator system. (author)

  1. Experimental studies on caisson-type porous seawalls

    Science.gov (United States)

    Zhu, Shutang; Chwang, A. T.

    2002-08-01

    This paper presents experimental studies on the reflection characteristics of caisson-type porous seawalls under designed wave conditions. The results of physical model experiments are plotted and discussed. Comparisons between experimental results and analytical predictions are also made and the agreement is found to be very good.

  2. Office type's association to employees' welfare: Three studies.

    Science.gov (United States)

    Danielsson, Christina Bodin

    2016-08-12

    The workplace is important for employees' daily life and well-being. This article investigates exploratory the office design's role for employees' welfare from different perspectives. By comparing different studies of the office, type's influence on different factors of employees' welfare the aim is to see if any common patterns exist in office design's impact. The three included studies investigate office type's association with employees' welfare by measuring its influence on: a) perception of leadership, b) sick leave, and c) job satisfaction.The sample consists of office employees from a large, national representative work environment survey that work in one of the seven identified office types in contemporary office design: (1) cell-offices; (2) shared-room offices; (3) small, (4) medium-sized and (5) large open-plan offices; (6) flex-offices and (7) combi-offices. Statistical method used is multivariate logistic and linear regression analysis with adjustment for background factors. Overall results show that shared-room office, traditional open plan offices and flex-office stand out negatively, but to different degree(s) on the different outcomes measured. This explorative comparison of different studies finds a pattern of office types that repeatedly show indications of negative influence on employees' welfare, but further studies are needed to clarify this.

  3. Language Learner Motivational Types: A Cluster Analysis Study

    Science.gov (United States)

    Papi, Mostafa; Teimouri, Yasser

    2014-01-01

    The study aimed to identify different second language (L2) learner motivational types drawing on the framework of the L2 motivational self system. A total of 1,278 secondary school students learning English in Iran completed a questionnaire survey. Cluster analysis yielded five different groups based on the strength of different variables within…

  4. Wind Turbine Gearbox Condition Monitoring Round Robin Study - Vibration Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Sheng, S.

    2012-07-01

    The Gearbox Reliability Collaborative (GRC) at the National Wind Technology Center (NWTC) tested two identical gearboxes. One was tested on the NWTCs 2.5 MW dynamometer and the other was field tested in a turbine in a nearby wind plant. In the field, the test gearbox experienced two oil loss events that resulted in damage to its internal bearings and gears. Since the damage was not severe, the test gearbox was removed from the field and retested in the NWTCs dynamometer before it was disassembled. During the dynamometer retest, some vibration data along with testing condition information were collected. These data enabled NREL to launch a Wind Turbine Gearbox Condition Monitoring Round Robin project, as described in this report. The main objective of this project was to evaluate different vibration analysis algorithms used in wind turbine condition monitoring (CM) and find out whether the typical practices are effective. With involvement of both academic researchers and industrial partners, the project sets an example on providing cutting edge research results back to industry.

  5. Short-term trajectories of use of a caloric-monitoring mobile phone app among patients with type 2 diabetes mellitus in a primary care setting.

    Science.gov (United States)

    Goh, Glenn; Tan, Ngiap Chuan; Malhotra, Rahul; Padmanabhan, Uma; Barbier, Sylvaine; Allen, John Carson; Østbye, Truls

    2015-02-03

    of being an Intermittent-Waning User relative to a Minimal User was also significantly higher for those with higher exercise motivation scores at baseline (OR 1.82, 95% CI 1.00-3.32). This study provides insight into the nature and extent of usage of a caloric-monitoring app among patients with type 2 diabetes and managed in primary care. The application of LCGM provides a useful framework for evaluating future app use in other patient populations.

  6. Ultrasound monitoring of the influence of different accelerating admixtures and cement types for shotcrete on setting and hardening behaviour

    International Nuclear Information System (INIS)

    Belie, N. de; Grosse, C.U.; Kurz, J.; Reinhardt, H.-W.

    2005-01-01

    The possible use of ultrasound measurements for monitoring setting and hardening of mortar containing different accelerating admixtures for shotcrete was investigated. The sensitivity to accelerator type (alkaline aluminate or alkali-free) and dosage, and accelerator-cement compatibility were evaluated. Furthermore, a new automatic onset picking algorithm for ultrasound signals was tested. A stepwise increase of the accelerator dosage resulted in increasing values for the ultrasound pulse velocity at early ages. In the accelerated mortar no dormant period could be noticed before the pulse velocity started to increase sharply, indicating a quick change in solid phase connectivity. The alkaline accelerator had a larger effect than the alkali-free accelerator, especially at ages below 90 min. The effect of the alkali-free accelerator was at very early age more pronounced on mortar containing CEM I in comparison with CEM II, while the alkaline accelerator had a larger influence on mortar containing CEM II. The increase of ultrasound energy could be related to the setting phenomenon and the maximum energy was reached when the end of workability was approached. Only the alkaline accelerator caused a significant reduction in compressive strength and this for all the dosages tested

  7. Upgrades of DARWIN, a dose and spectrum monitoring system applicable to various types of radiation over wide energy ranges

    Science.gov (United States)

    Sato, Tatsuhiko; Satoh, Daiki; Endo, Akira; Shigyo, Nobuhiro; Watanabe, Fusao; Sakurai, Hiroki; Arai, Yoichi

    2011-05-01

    A dose and spectrum monitoring system applicable to neutrons, photons and muons over wide ranges of energy, designated as DARWIN, has been developed for radiological protection in high-energy accelerator facilities. DARWIN consists of a phoswitch-type scintillation detector, a data-acquisition (DAQ) module for digital waveform analysis, and a personal computer equipped with a graphical-user-interface (GUI) program for controlling the system. The system was recently upgraded by introducing an original DAQ module based on a field programmable gate array, FPGA, and also by adding a function for estimating neutron and photon spectra based on an unfolding technique without requiring any specific scientific background of the user. The performance of the upgraded DARWIN was examined in various radiation fields, including an operational field in J-PARC. The experiments revealed that the dose rates and spectra measured by the upgraded DARWIN are quite reasonable, even in radiation fields with peak structures in terms of both spectrum and time variation. These results clearly demonstrate the usefulness of DARWIN for improving radiation safety in high-energy accelerator facilities.

  8. Upgrades of DARWIN, a dose and spectrum monitoring system applicable to various types of radiation over wide energy ranges

    International Nuclear Information System (INIS)

    Sato, Tatsuhiko; Satoh, Daiki; Endo, Akira; Shigyo, Nobuhiro; Watanabe, Fusao; Sakurai, Hiroki; Arai, Yoichi

    2011-01-01

    A dose and spectrum monitoring system applicable to neutrons, photons and muons over wide ranges of energy, designated as DARWIN, has been developed for radiological protection in high-energy accelerator facilities. DARWIN consists of a phoswitch-type scintillation detector, a data-acquisition (DAQ) module for digital waveform analysis, and a personal computer equipped with a graphical-user-interface (GUI) program for controlling the system. The system was recently upgraded by introducing an original DAQ module based on a field programmable gate array, FPGA, and also by adding a function for estimating neutron and photon spectra based on an unfolding technique without requiring any specific scientific background of the user. The performance of the upgraded DARWIN was examined in various radiation fields, including an operational field in J-PARC. The experiments revealed that the dose rates and spectra measured by the upgraded DARWIN are quite reasonable, even in radiation fields with peak structures in terms of both spectrum and time variation. These results clearly demonstrate the usefulness of DARWIN for improving radiation safety in high-energy accelerator facilities.

  9. A Statistical Study of Interplanetary Type II Bursts: STEREO Observations

    Science.gov (United States)

    Krupar, V.; Eastwood, J. P.; Magdalenic, J.; Gopalswamy, N.; Kruparova, O.; Szabo, A.

    2017-12-01

    Coronal mass ejections (CMEs) are the primary cause of the most severe and disruptive space weather events such as solar energetic particle (SEP) events and geomagnetic storms at Earth. Interplanetary type II bursts are generated via the plasma emission mechanism by energetic electrons accelerated at CME-driven shock waves and hence identify CMEs that potentially cause space weather impact. As CMEs propagate outward from the Sun, radio emissions are generated at progressively at lower frequencies corresponding to a decreasing ambient solar wind plasma density. We have performed a statistical study of 153 interplanetary type II bursts observed by the two STEREO spacecraft between March 2008 and August 2014. These events have been correlated with manually-identified CMEs contained in the Heliospheric Cataloguing, Analysis and Techniques Service (HELCATS) catalogue. Our results confirm that faster CMEs are more likely to produce interplanetary type II radio bursts. We have compared observed frequency drifts with white-light observations to estimate angular deviations of type II burst propagation directions from radial. We have found that interplanetary type II bursts preferably arise from CME flanks. Finally, we discuss a visibility of radio emissions in relation to the CME propagation direction.

  10. Blackbird Creek Monitoring Program to Study the impact of Climate Change and Land Use

    Science.gov (United States)

    Ozbay, G.; Chintapenta, L. K.; Roeske, K. P.; Stone, M.; Phalen, L.

    2014-12-01

    The Blackbird Creek Monitoring Program at Delaware State University continues to utilize various perspectives to study the dynamics of one of Delaware's most pristine ecosystems. The water quality of Blackbird Creek has been constantly monitored for 3 years and correlated with the rain and storm events. Soil nutrients composition has been studied by extracting the water associated with soil aggregates and analyzing the levels of different nutrients. Soil quality is also assessed for heavy metals to identify potential human impact that may affect the health of ecosystem. Within the Blackbird Creek there is a threat to native plant communities from invasive plant species as they alter the ecosystem dynamics. Saltmarsh cord grass (Spartina alterniflora) and common reed (Phragmites australius) are the common wetland plants. Aerial mapping of the creek has been conducted to determine the area covered by invasive plant species. The microbial community structure plays a key role in soil carbon and nitrogen cycles in the ecosystem. Molecular analysis has been performed to study the microbial diversity with respect to the type of marsh grasses. This program has also incorporated the use of diatoms as biological indicators to assess the health of ecosystem and correlate that data with physical and chemical water quality data. The abundance and diversity of macro fauna such as blue crabs, fish and other significant species has also been studied. Stable isotopic analysis of these macro fauna has also been performed to study the food web. The results from this program will be helpful in addressing environmental challenges and designing management strategies.

  11. Study of monitoring protection of radionuclides contamination in organism by autoradiography

    International Nuclear Information System (INIS)

    Zhu Shoupeng; Kang Baoan; He Guangren

    1987-01-01

    In view of the exceptionally important role of the medical radiation protection in human health, the authors try to study on the monitoring of internal contamination of radionuclides in organism by different autoradiographic methods, such as: monitoring of the body retention of isolated or combined radionuclides by freezing microautoradiography; monitoring of blood, bone marrow and excreta radioactive samples by smear autoradiography; differentiation of two radionuclides contamination by double radionuclide autoradiography; especially, monitoring of low level of radionuclides contamination by fluorescence sensitization autoradiography. The sensitivity of autoradiographic formation was increased by the scintillator by 10 times

  12. Study on Typhoon Characteristic Based on Bridge Health Monitoring System

    Directory of Open Access Journals (Sweden)

    Xu Wang

    2014-01-01

    Full Text Available Through the wind velocity and direction monitoring system installed on Jiubao Bridge of Qiantang River, Hangzhou city, Zhejiang province, China, a full range of wind velocity and direction data was collected during typhoon HAIKUI in 2012. Based on these data, it was found that, at higher observed elevation, turbulence intensity is lower, and the variation tendency of longitudinal and lateral turbulence intensities with mean wind speeds is basically the same. Gust factor goes higher with increasing mean wind speed, and the change rate obviously decreases as wind speed goes down and an inconspicuous increase occurs when wind speed is high. The change of peak factor is inconspicuous with increasing time and mean wind speed. The probability density function (PDF of fluctuating wind speed follows Gaussian distribution. Turbulence integral scale increases with mean wind speed, and its PDF does not follow Gaussian distribution. The power spectrum of observation fluctuating velocity is in accordance with Von Karman spectrum.

  13. [Study for portable dynamic ECG monitor and recorder].

    Science.gov (United States)

    Yang, Pengcheng; Li, Yongqin; Chen, Bihua

    2012-09-01

    This Paper presents a portable dynamic ECG monitor system based on MSP430F149 microcontroller. The electrocardiogram detecting system consists of ECG detecting circuit, man-machine interaction module, MSP430F149 and upper computer software. The ECG detecting circuit including a preamplifier, second-order Butterworth low-pass filter, high-pass filter, and 50Hz trap circuit to detects electrocardiogram and depresses various kinds of interference effectively. A microcontroller is used to collect three channel analog signals which can be displayed on TFT LCD. A SD card is used to record real-time data continuously and implement the FTA16 file system. In the end, a host computer system interface is also designed to analyze the ECG signal and the analysis results can provide diagnosis references to clinical doctors.

  14. Space Weather Monitoring for ISS Geomagnetic Storm Studies

    Science.gov (United States)

    Minow, Joseph I.; Parker, Linda Neergaard

    2013-01-01

    The International Space Station (ISS) space environments community utilizes near real time space weather data to support a variety of ISS engineering and science activities. The team has operated the Floating Potential Measurement Unit (FPMU) suite of plasma instruments (two Langmuir probes, a floating potential probe, and a plasma impedance probe) on ISS since 2006 to obtain in-situ measurements of plasma density and temperature along the ISS orbit and variations in ISS frame potential due to electrostatic current collection from the plasma environment (spacecraft charging) and inductive (vxB) effects from the vehicle motion across the Earth s magnetic field. An ongoing effort is to use FPMU for measuring the ionospheric response to geomagnetic storms at ISS altitudes and investigate auroral charging of the vehicle as it passes through regions of precipitating auroral electrons. This work is challenged by restrictions on FPMU operations that limit observation time to less than about a third of a year. As a result, FPMU campaigns ranging in length from a few days to a few weeks are typically scheduled weeks in advance for ISS engineering and payload science activities. In order to capture geomagnetic storm data under these terms, we monitor near real time space weather data from NASA, NOAA, and ESA sources to determine solar wind disturbance arrival times at Earth likely to be geoeffective (including coronal mass ejections and high speed streams associated with coronal holes) and activate the FPMU ahead of the storm onset. Using this technique we have successfully captured FPMU data during a number of geomagnetic storm periods including periods with ISS auroral charging. This presentation will describe the strategies and challenges in capturing FPMU data during geomagnetic storms, the near real time space weather resources utilized for monitoring the space weather environment, and provide examples of auroral charging data obtained during storm operations.

  15. Design of an Air Pollution Monitoring Campaign in Beijing for Application to Cohort Health Studies.

    Science.gov (United States)

    Vedal, Sverre; Han, Bin; Xu, Jia; Szpiro, Adam; Bai, Zhipeng

    2017-12-15

    No cohort studies in China on the health effects of long-term air pollution exposure have employed exposure estimates at the fine spatial scales desirable for cohort studies with individual-level health outcome data. Here we assess an array of modern air pollution exposure estimation approaches for assigning within-city exposure estimates in Beijing for individual pollutants and pollutant sources to individual members of a cohort. Issues considered in selecting specific monitoring data or new monitoring campaigns include: needed spatial resolution, exposure measurement error and its impact on health effect estimates, spatial alignment and compatibility with the cohort, and feasibility and expense. Sources of existing data largely include administrative monitoring data, predictions from air dispersion or chemical transport models and remote sensing (specifically satellite) data. New air monitoring campaigns include additional fixed site monitoring, snapshot monitoring, passive badge or micro-sensor saturation monitoring and mobile monitoring, as well as combinations of these. Each of these has relative advantages and disadvantages. It is concluded that a campaign in Beijing that at least includes a mobile monitoring component, when coupled with currently available spatio-temporal modeling methods, should be strongly considered. Such a campaign is economical and capable of providing the desired fine-scale spatial resolution for pollutants and sources.

  16. Design of an Air Pollution Monitoring Campaign in Beijing for Application to Cohort Health Studies

    Directory of Open Access Journals (Sweden)

    Sverre Vedal

    2017-12-01

    Full Text Available No cohort studies in China on the health effects of long-term air pollution exposure have employed exposure estimates at the fine spatial scales desirable for cohort studies with individual-level health outcome data. Here we assess an array of modern air pollution exposure estimation approaches for assigning within-city exposure estimates in Beijing for individual pollutants and pollutant sources to individual members of a cohort. Issues considered in selecting specific monitoring data or new monitoring campaigns include: needed spatial resolution, exposure measurement error and its impact on health effect estimates, spatial alignment and compatibility with the cohort, and feasibility and expense. Sources of existing data largely include administrative monitoring data, predictions from air dispersion or chemical transport models and remote sensing (specifically satellite data. New air monitoring campaigns include additional fixed site monitoring, snapshot monitoring, passive badge or micro-sensor saturation monitoring and mobile monitoring, as well as combinations of these. Each of these has relative advantages and disadvantages. It is concluded that a campaign in Beijing that at least includes a mobile monitoring component, when coupled with currently available spatio-temporal modeling methods, should be strongly considered. Such a campaign is economical and capable of providing the desired fine-scale spatial resolution for pollutants and sources.

  17. A study of groundwater monitoring data analysis using Artificial Neural Network model

    International Nuclear Information System (INIS)

    Watanabe, Kunio; Gautam, M.R.; Saegusa, Hiromitsu

    2003-05-01

    The results of groundwater flow modeling are to be justified using groundwater monitoring data in the hydrogeological characterization. On the other hand, hydraulic continuities of the geological structures, all of which are considered to have great effect on groundwater flow and/or groundwater quality, are to be estimated using the groundwater flow monitoring data with hydraulic response to some impacts such as borehole drilling, pumping test and so on. Therefore, the groundwater monitoring is important for characterizing the geological and hydrogeological environments. In order to characterize of hydrogeological environment using the monitoring data, it is important to evaluate the influence of artificial and natural impact on the monitoring data. In this study, the following three research works are carried out based on the groundwater monitoring data collected at the Tono area. Artificial Neural Network (ANN) was adopted as the tool for monitoring data analysis. Runoff analysis for assessment of importance of soil moisture on runoff estimation in a catchment. Analysis of water level fluctuation for determination influence factors in the water level fluctuation and for filtering out the influence factors from the water level data . Analysis of hydraulic pressure fluctuation in deep geological formations for hydrogeological characterization and assessment of human influence on the pore pressure in deep formation. Through this study, applicability of ANN for analysis and interpretation of the groundwater monitoring data could be confirmed and methodology for utilization the monitoring data for understanding and characterization of hydrogeological environment could be developed. (author)

  18. Studies on the crossed flow type MHD turbines

    International Nuclear Information System (INIS)

    Hori, Toshihiro; Katsurai, Makoto

    1981-01-01

    The studies on crossed flow type MHD turbines were performed to improve its characteristics. Two-dimensional models were considered for the analytical studies. To compensate the edge effect of magnetic field, the magnetic field gradient by tapering was considered. An iron-core structure and an air-core structure were investigated. It was found that the ideal characteristics can be obtained when there is the tapered length more than one wave length. Various methods for the improvement of magnetic field were studied in the case of practical crossed flow type MHD turbines. The methods were the adjustment with an iron-core, and the adoption of a curved channel. It can be expected to obtain the internal efficiency of more than 70 percent, when the number of pole-pairs is more than 10 and the radius of curvature of a few times of rotor radius is given to a curved channel. (Kato, T.)

  19. [Monitoring the use of health-related quality of life measurements in Korean studies of patients with diabetes].

    Science.gov (United States)

    Lee, Eun-Hyun; Kim, Chun-Ja; Cho, Soo-Yeon; Chae, Hyun-Ju; Lee, Sunhee; Kim, Eun Jung

    2011-08-01

    The purpose of this study was to monitor the use of health-related quality of life (HRQOL) instruments in Korean studies of patients with diabetes. Of 86 Korean studies initially identified, 17 studies met the inclusion criteria. For each study, a description of the instrument and its psychometric properties were monitored by the Instrument Review Criteria of the Scientific Advisory Committee. These criteria include conceptual definition, attributes, taxonomy, reliability, validity, responsiveness, administrative mode, and language adaptations. Five generic and one diabetes specific type questionnaires were identified from the 17 studies. Of those studies, conceptual definitions with the attributes of multi-dimension and subjectiveness were provided for 11 studies (71%). In the analysis of conceptual taxonomy, only 6 studies were classified as HRQOL, while other studies were done as QOL or health status. In monitoring of psychometric properties, reliability, validity, and responsiveness were reported for 88.2%, 64.7%, and 29.4%, respectively. One generic instrument was developed with a Korean population, while the other instruments were developed for Western countries. However, language adaptations were performed for only a few of the instruments. The psychometric properties including responsiveness of most instruments warrants further research, and the development of diabetes-specific HRQOL measurements should be sought to facilitate intervention outcomes across Korean studies of patients with diabetes.

  20. Intensive monitoring of new drugs based on first prescription signals from pharmacists : a pilot study

    NARCIS (Netherlands)

    Van Grootheest, AC; Groote, JK; de Jong-van den Berg, LTW

    Background Intensive monitoring can be a valuable tool in the early detection of adverse drug reactions, especially of new drugs. Aim of this pilot study was to investigate the practical possibilities of a system of intensive monitoring, using the pharmacy computer system to detect the first

  1. Evaluation of a combined blood glucose monitoring and gaming system (Didget®) for motivation in children, adolescents, and young adults with type 1 diabetes.

    Science.gov (United States)

    Klingensmith, Georgeanna J; Aisenberg, Javier; Kaufman, Francine; Halvorson, Mary; Cruz, Eric; Riordan, Mary Ellen; Varma, Chandrasekhar; Pardo, Scott; Viggiani, Maria T; Wallace, Jane F; Schachner, Holly C; Bailey, Timothy

    2013-08-01

    The purpose of this study was to assess the performance and acceptability of a blood glucose meter coupled with a gaming system for children, adolescents, and young adults with type 1 diabetes. During an in-clinic visit, duplicate blood samples were tested by subjects (N = 147; aged 5-24 yr) and health care providers (HCPs) to evaluate the accuracy and precision of the Didget® system. Subjects' meter results were compared against Yellow Springs Instruments (YSI) reference results and HCP results using least squares regression and error grid analyses. Precision was measured by average within-subject and within-HCP coefficient of variation (CV). During the home-use component of this study, subjects (n = 58) tested their blood glucose at least two to three times daily for 3-5 d to evaluate routine use of the system. Subjects' meter results showed significant correlations with both YSI (r(2) = 0.94; p motivating, and helpful for building good blood glucose monitoring habits. Most HCPs agreed that the system fulfilled a need in diabetes management. In conclusion, the Didget® system was precise and clinically accurate in the hands of children, adolescents, and young adults with type 1 diabetes. © 2011 John Wiley & Sons A/S.

  2. Investigating and comparing the relationship between parental monitoring types and perceived parenting styles of the Turkish students

    OpenAIRE

    Öğretir Özçelik, Ayse Dilek

    2017-01-01

    The relationship between parental monitoring and parental styles are considered as an important subject for child development field. The aim of this article is to analyze the perceptions of the adolescents about their parents’ parental monitoring and parenting styles in terms of the participants’ gender, family education and family jobs status. The sample size is 252 adolescents with 158 female nd 94 male students. The data were collected by the Parental Monitoring Instrument (PMI) and the Pa...

  3. Study on steam pressure characteristics in various types of nozzles

    Science.gov (United States)

    Firman; Anshar, Muhammad

    2018-03-01

    Steam Jet Refrigeration (SJR) is one of the most widely applied technologies in the industry. The SJR system was utilizes residual steam from the steam generator and then flowed through the nozzle to a tank that was containing liquid. The nozzle converts the pressure energy into kinetic energy. Thus, it can evaporate the liquid briefly and release it to the condenser. The chilled water, was produced from the condenser, can be used to cool the product through a heat transfer process. This research aims to study the characteristics of vapor pressure in different types of nozzles using a simulation. The Simulation was performed using ANSYS FLUENT software for nozzle types such as convergent, convrgent-parallel, and convergent-divergent. The results of this study was presented the visualization of pressure in nozzles and was been validated with experiment data.

  4. Real-time continuous glucose monitoring as a tool to prevent severe hypoglycaemia in selected pregnant women with Type 1 diabetes

    DEFF Research Database (Denmark)

    Secher, A L; Stage, E; Ringholm, Lene

    2014-01-01

    AIMS: Among women with Type 1 diabetes who have had severe hypoglycaemia the year before pregnancy, 70% also experience this complication in pregnancy, and particularly in the first half of pregnancy. We evaluated whether routine use of real-time continuous glucose monitoring from early pregnancy...... onwards could prevent severe hypoglycaemia in these women. METHODS: All 136 consecutive pregnant women with Type 1 diabetes referred to our centre were asked about severe hypoglycaemic events in the year before pregnancy and early in pregnancy at their first antenatal visit. Women with a relevant recent...... history were informed about their additional high risk of severe hypoglycaemia, their treatment was focused on restricted insulin doses during the first 16 gestational weeks, and they were offered real-time continuous glucose monitoring on top of self-monitored plasma glucose measurements. RESULTS: Among...

  5. WIYN Open Cluster Study: Tidal Interactions in Solar type Binaries

    OpenAIRE

    Meibom, S.; Mathieu, R. D.

    2003-01-01

    We present an ongoing study on tidal interactions in late-type close binary stars. New results on tidal circularization are combined with existing data to test and constrain theoretical predictions of tidal circularization in the pre-main-sequence (PMS) phase and throughout the main-sequence phase of stellar evolution. Current data suggest that tidal circularization during the PMS phase sets the tidal cutoff period for binary populations younger than ~1 Gyr. Binary populations older than ~1 G...

  6. Use of real time continuous glucose monitoring and intravenous insulin in type 1 diabetic mothers to prevent respiratory distress and hypoglycaemia in infants

    Directory of Open Access Journals (Sweden)

    Passaro Patrizia

    2008-07-01

    Full Text Available Abstract Background Pregnancy in Type 1 diabetic patients is a precarious condition, both for mother and fetus with increased the risk of prematurity and, immediately after delivery with risk of respiratory distress syndrome and hypoglycaemia in newborns. A strict control and monitoring of diabetes throughout pregnancy is important in reducing the impact of the disease on the fetus and newborn. In recent years many new technologies have been introduced to ameliorate diabetes monitoring, where the last is the Real-time Continuous Glucose Monitoring System (RT-CGMS. Methods In the last three years, 72 h continuous glucose monitoring system (RT-CGMS (Medtronic, CA was performed in 18 pregnant women with Type 1 diabetes in two moments of pregnancy: during treatment with betamethasone to prevent respiratory distress and during delivery. In both cases insulin was administered intravenous and the dose was changed on the basis of glycaemia. Results The results present the use of this new technique during two topics moments of pregnancy of type 1 diabetes patients when is very important intensively to monitor diabetes and to obtain the well being of the fetus. No infant experimented hypoglycaemia or respiratory distress syndrome at the moment and in the first hours after the birth. Conclusion We wish to stress the importance reducing glycaemia during administration of betamethasone and during labor. It is conceivable that the scarce attention paid to monitoring glucose levels in diabetic mothers during labor in gynaecological world may be due to the difficulty in glucose monitoring with the devices until now available. Hopefully, our anecdotal account may prompt improvements with RT-CGMS, and may lead to a better approach to the problem, thereby changing the prognosis of infants born to diabetic mothers.

  7. Study on Monitoring Rock Burst through Drill Pipe Torque

    Directory of Open Access Journals (Sweden)

    Zhonghua Li

    2015-01-01

    Full Text Available This paper presents a new method to identify the danger of rock burst from the response of drill pipe torque during drilling process to overcome many defects of the conventional volume of drilled coal rubble method. It is based on the relationship of rock burst with coal stress and coal strength. Through theoretic analysis, the change mechanism of drill pipe torque and the relationship of drill pipe torque with coal stress, coal strength, and drilling speed are investigated. In light of the analysis, a new device for testing drill pipe torque is developed and a series of experiments is performed under different conditions; the results show that drill pipe torque linearly increases with the increase of coal stress and coal strength; the faster the drilling speed, the larger the drill pipe torque, and vice versa. When monitoring rock burst by drill pipe torque method, the index of rock burst is regarded as a function in which coal stress index and coal strength index are principal variables. The results are important for the forecast of rock burst in coal mine.

  8. Monitorizing nitinol alloy surface reactions for biofouling studies

    International Nuclear Information System (INIS)

    Dinu, C.Z.; Dinca, V.C.; Soare, S.; Moldovan, A.; Smarandache, D.; Scarisoareanu, N.; Barbalat, A.; Birjega, R.; Dinescu, M.; DiStefano, V. Ferrari

    2007-01-01

    Growth and deposition of unwanted bacteria on implant metal alloys affect their use as biomedical samples. Monitoring any bacterial biofilm accumulation will provide early countermeasures. For a reliable antifouling strategy we prepared nitinol (NiTi) thin films on Ti-derived substrates by using a pulsed laser deposition (PLD) method. As the microstructure of Ti-alloy is dictated by the tensile strength, fatigue and the fracture toughness we tested the use of hydrogen as an alloying element. X-ray diffraction (XRD), scanning electron microscopy (SEM) and atomic force microscopy (AFM) investigated the crystalline structure, chemical composition and respectively the surface morphology of the nitinol hydrogen and hydrogen-free samples. Moreover, the alloys were integrated and tested using a cellular metric and their responses were systematic evaluated and quantified. Our attractive approach is meant to select the suitable components for an effective and trustworthy anti-fouling strategy. A greater understanding of such processes should lead to novel and effective control methods that would improve in the future implant stability and capabilities

  9. Study and project of a radiation monitoring system in ships

    International Nuclear Information System (INIS)

    Morgado, Mario Monteiro

    1998-01-01

    In this work we present the project and the development of a radiation detection system for use in ships, called RADINAC. This system was developed to measure the radiation in several points of the ship and to give the dose rates and total dose. The radioactive activity of the sea water is also measured. The project was based on a system developed in the middle of the seventies which is not working due to the lack of some mechanical and electronic components. The RADINAC system was developed in order to nationalize and modernize the old project. The detectors used are plastic scintillator to measure the sea water radioactive activity and ionization chambers to measure the dose rates. The nuclear instrumentation has only three imported items: acquisition data board, picoamperimeter and photomultiplier tube. All the other items are made in Brazil. With regard to the data acquisition, we used the Labwindows software to create the 'virtual instruments' in order to display the data on the computer monitor. (author)

  10. Monitoring and discussing health-related quality of life in adolescents with type 1 diabetes improve psychosocial well-being: a randomized controlled trial

    NARCIS (Netherlands)

    de Wit, M.; Delemarre-van d Waal, H.A.; Bokma, J.A.; Haasnoot, K.; Houdijk, M.C.; Gemke, R.J.B.J.; Snoek, F.J.

    2008-01-01

    OBJECTIVE - To test the effects of monitoring and discussing of health-related quality of life (HRQoL) in adolescents with type 1 diabetes in a multicenter randomized controlled trial. RESEARCH DESIGN AND METHODS - Four centers were randomly assigned to the HRQoL intervention (46 adolescents) or

  11. Advanced inoperable type B3 thymoma: monitoring of a novel therapeutic approach with radio-chemotherapy and sorafenib by FDG-PET and CT

    International Nuclear Information System (INIS)

    Winder, T.; Gasser, K.; Schuster, A.; Becherer, A.; Vries, A. de; Gruber-Moesenbacher, U.; Muendlein, A.; Drexel, H.; Lang, A.

    2010-01-01

    This report highlights the benefit of radio-chemotherapy followed by sorafenib in a 55 years old woman, diagnosed with an inoperable type B3 thymoma and illustrates the potential usefulness of 18 F-FDG in monitoring treatment with sorafenib. (orig.)

  12. Parametric study on beta-type Stirling engine

    International Nuclear Information System (INIS)

    Abuelyamen, A.; Ben-Mansour, R.; Abualhamayel, H.; Mokheimer, Esmail M.A.

    2017-01-01

    Highlights: • A parametric study of laminar flow for a β-type Stirling engine was performed. • The optimum charge pressure varies from gas to another. • Stirling engine runs better below the optimum charge pressure for H 2 and He. • Power output increases with temperature while thermal efficiency decreases. • For air and He, output power increases with temperature differences (T H − T C ). - Abstract: In this work, a parametric study on a β-type Stirling engine with no regenerator was conducted numerically using ANSYS fluent 14.5 software. The three parameters that were studied are; initial charge pressure, thermal boundary condition; and three different types of working fluids (Air, He and H 2 ). Variable thermal properties of these gases were adopted to get more realistic results. The results include a comparison of the amount of heat transfer, power output, and thermal efficiency. It was found that the best engine performance is achieved when H 2 gas is used as working fluid. Moreover, results revealed that each of the power output and the efficiency has different optimum charge pressure. Additionally, it was found that there is a small variation in the pressure across the engine chambers, which results in miss matching between the net heat transfer rates and power output calculated from PV-diagram. This error is higher when the air is used as working fluid, especially at high charge pressure.

  13. HIV-1 drug resistance mutations among antiretroviral-naive HIV-1-infected patients in Asia: results from the TREAT Asia Studies to Evaluate Resistance-Monitoring Study.

    Science.gov (United States)

    Sungkanuparph, Somnuek; Oyomopito, Rebecca; Sirivichayakul, Sunee; Sirisanthana, Thira; Li, Patrick C K; Kantipong, Pacharee; Lee, Christopher K C; Kamarulzaman, Adeeba; Messerschmidt, Liesl; Law, Matthew G; Phanuphak, Praphan

    2011-04-15

    Of 682 antiretroviral-naïve patients initiating antiretroviral therapy in a prospective, multicenter human immunodeficiency virus type 1 (HIV-1) drug resistance monitoring study involving 8 sites in Hong Kong, Malaysia, and Thailand, the prevalence of patients with ≥1 drug resistance mutation was 13.8%. Primary HIV drug resistance is emerging after rapid scaling-up of antiretroviral therapy use in Asia.

  14. Effects of telemedicine in the treatment of patients with type 2 diabetes – a study protocol

    DEFF Research Database (Denmark)

    Hansen, Caroline Raun; Perrild, Hans; Koefoed, Birgitte Gade

    2013-01-01

    is to examine whether telemedicine conferences with a nurse can contribute to achieving good diabetes control among patients with poorly regulated type 2 diabetes. MATERIAL AND METHODS: A total of 165 patients with type 2 diabetes who have formerly undergone a rehabilitation programme are randomized to either...... telemedicine intervention or usual care. The intervention lasts for 32 weeks and consists of monthly videoconferences with a nurse from a health-care centre as an add-on to usual care. Blood sugar, blood pressure and weight are regularly self-monitored and measurements are automatically transferred......: The study will examine whether telemedicine technology can contribute to achieving good diabetes regulation. FUNDING: The City of Copenhagen and the Prevention Fund of the Capital Region of Denmark funded the project. Also "Smedemester Niels Hansen og Hustru Johanne F. Frederiksens Legat" has supported...

  15. Risk-adapted monitoring is not inferior to extensive on-site monitoring: Results of the ADAMON cluster-randomised study.

    Science.gov (United States)

    Brosteanu, Oana; Schwarz, Gabriele; Houben, Peggy; Paulus, Ursula; Strenge-Hesse, Anke; Zettelmeyer, Ulrike; Schneider, Anja; Hasenclever, Dirk

    2017-12-01

    Background According to Good Clinical Practice, clinical trials must protect rights and safety of patients and make sure that the trial results are valid and interpretable. Monitoring on-site has an important role in achieving these objectives; it controls trial conduct at trial sites and informs the sponsor on systematic problems. In the past, extensive on-site monitoring with a particular focus on formal source data verification often lost sight of systematic problems in study procedures that endanger Good Clinical Practice objectives. ADAMON is a prospective, stratified, cluster-randomised, controlled study comparing extensive on-site monitoring with risk-adapted monitoring according to a previously published approach. Methods In all, 213 sites from 11 academic trials were cluster-randomised between extensive on-site monitoring (104) and risk-adapted monitoring (109). Independent post-trial audits using structured manuals were performed to determine the frequency of major Good Clinical Practice findings at the patient level. The primary outcome measure is the proportion of audited patients with at least one major audit finding. Analysis relies on logistic regression incorporating trial and monitoring arm as fixed effects and site as random effect. The hypothesis was that risk-adapted monitoring is non-inferior to extensive on-site monitoring with a non-inferiority margin of 0.60 (logit scale). Results Average number of monitoring visits and time spent on-site was 2.1 and 2.7 times higher in extensive on-site monitoring than in risk-adapted monitoring, respectively. A total of 156 (extensive on-site monitoring: 76; risk-adapted monitoring: 80) sites were audited. In 996 of 1618 audited patients, a total of 2456 major audit findings were documented. Depending on the trial, findings were identified in 18%-99% of the audited patients, with no marked monitoring effect in any of the trials. The estimated monitoring effect is -0.04 on the logit scale with two-sided 95

  16. Validation of the Hirst-Type Spore Trap for Simultaneous Monitoring of Prokaryotic and Eukaryotic Biodiversities in Urban Air Samples by Next-Generation Sequencing.

    Science.gov (United States)

    Núñez, Andrés; Amo de Paz, Guillermo; Ferencova, Zuzana; Rastrojo, Alberto; Guantes, Raúl; García, Ana M; Alcamí, Antonio; Gutiérrez-Bustillo, A Montserrat; Moreno, Diego A

    2017-07-01

    Pollen, fungi, and bacteria are the main microscopic biological entities present in outdoor air, causing allergy symptoms and disease transmission and having a significant role in atmosphere dynamics. Despite their relevance, a method for monitoring simultaneously these biological particles in metropolitan environments has not yet been developed. Here, we assessed the use of the Hirst-type spore trap to characterize the global airborne biota by high-throughput DNA sequencing, selecting regions of the 16S rRNA gene and internal transcribed spacer for the taxonomic assignment. We showed that aerobiological communities are well represented by this approach. The operational taxonomic units (OTUs) of two traps working synchronically compiled >87% of the total relative abundance for bacterial diversity collected in each sampler, >89% for fungi, and >97% for pollen. We found a good correspondence between traditional characterization by microscopy and genetic identification, obtaining more-accurate taxonomic assignments and detecting a greater diversity using the latter. We also demonstrated that DNA sequencing accurately detects differences in biodiversity between samples. We concluded that high-throughput DNA sequencing applied to aerobiological samples obtained with Hirst spore traps provides reliable results and can be easily implemented for monitoring prokaryotic and eukaryotic entities present in the air of urban areas. IMPORTANCE Detection, monitoring, and characterization of the wide diversity of biological entities present in the air are difficult tasks that require time and expertise in different disciplines. We have evaluated the use of the Hirst spore trap (an instrument broadly employed in aerobiological studies) to detect and identify these organisms by DNA-based analyses. Our results showed a consistent collection of DNA and a good concordance with traditional methods for identification, suggesting that these devices can be used as a tool for continuous

  17. In situ monitoring of stacking fault formation and its carrier lifetime mediation in p-type 4H-SiC

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Bin, E-mail: chenbinmse@gmail.com; Chen, Jun; Yao, Yuanzhao; Sekiguchi, Takashi [National Institute for Materials Science, Tsukuba, Ibaraki 305-0044 (Japan); Matsuhata, Hirofumi; Okumura, Hajime [National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305-8568 (Japan)

    2014-07-28

    Using the fine control of an electron beam (e-beam) in scanning electron microscopy with the capabilities of both electrical and optical imaging, the stacking fault (SF) formation together with its tuning of carrier lifetime was in situ monitored and investigated in p-type 4H-SiC homoepitaxial films. The SFs were formed through engineering basal plane dislocations with the energy supplied by the e-beam. The e-beam intensity required for the SF formation in the p-type films was ∼100 times higher than that in the n-type ones. The SFs reduced the minority-carrier lifetime in the p-type films, which was opposite to that observed in the n-type case. The reason for the peculiar SF behavior in the p-type 4H-SiC is discussed with the cathodoluminescence results.

  18. Ports: Definition and study of types, sizes and business models

    Directory of Open Access Journals (Sweden)

    Ivan Roa

    2013-09-01

    Full Text Available Purpose: In the world today there are thousands of port facilities of different types and sizes, competing to capture some market share of freight by sea, mainly. This article aims to determine the type of port and the most common size, in order to find out which business model is applied in that segment and what is the legal status of the companies of such infrastructure.Design/methodology/approach: To achieve this goal, we develop a research on a representative sample of 800 ports worldwide, which manage 90% of the containerized port loading. Then you can find out the legal status of the companies that manage them.Findings: The results indicate a port type and a dominant size, which are mostly managed by companies subject to a concession model.Research limitations/implications: In this research, we study only those ports that handle freight (basically containerized, ignoring other activities such as fishing, military, tourism or recreational.Originality/value: This is an investigation to show that the vast majority of the studied segment port facilities are governed by a similar corporate model and subject to pressure from the markets, which increasingly demand efficiency and service. Consequently, we tend to concession terminals to private operators in a process that might be called privatization, but in the strictest sense of the term, is not entirely realistic because the ownership of the land never ceases to be public

  19. A study on hazard types occurring in hydrogen facilities

    International Nuclear Information System (INIS)

    Cho, Nam Chul; Jae, Moo Sung; Eon, Yang Joon

    2004-01-01

    Hydrogen has ideal characteristics as an energy carrier. Hydrogen can be used as a clean fuel in a variety of energy end-use sectors including the conversion to electricity. After combustion, it produces only water. Therefore, the concept of hydrogen energy system has attracted much interest worldwide. But hydrogen has a defect that the explosion risk is high to an inflammable gas of a colorless, tasteless and odorless. Therefore, to use the hydrogen to the source of energy, hydrogen accident sequences and causes analysis must be needed. For this, hazard types occurring in hydrogen facilities have been considered through the case of domestic and foreign hydrogen accident in this study and hazard types to be considered are ignition, leaks, hydrogen dispersion, fire an explosion, storage vessel failure, vent and exhaust system, purging, condensation of air, hydrogen embrittlement, physiological hazard, and collisions during transportation

  20. Physicochemical study of some types of Algerian honeys

    Directory of Open Access Journals (Sweden)

    Djahida. Nabti

    2016-09-01

    Full Text Available The modern bee-keeping proposes various types of honeys of floral and geographical origin, of very varied savor and aspect. It is often the only source of sugar of the most withdrawn indigenous populations of the tropical forests. Good for health, honey is also for the environment. The present manuscript is to determine its physicochemical characteristics, six types of samples were collected in various areas of the East of Algeria. These honeys are analyzed for the determination of the pH, the water content, electric conductivity, the ashes content, acidity, and the content of hydroxyl methylfurfural (HMF, the index of diastase (I.D. The results showed that there were differences of a honeys samples to the other and they which they all answer almost the international norms. The physicochemical analyzes studied is to control quality of Algerian honey who is considered an indicator of the environmental pollution.

  1. A longitudinal study of CMRGlu in dementia of Alzheimer type

    Energy Technology Data Exchange (ETDEWEB)

    Kuwabara, Yasuo; Ichiya, Yuichi; Ichimiya, Atsushi; Sasaki, Masayuki; Akashi, Yuko; Yoshida, Tsuyoshi; Fukumura, Toshimitsu; Masuda, Kouji [Kyushu Univ., Fukuoka (Japan). Faculty of Medicine

    1994-10-01

    We studied the serial changes of CMRGlu in 6 patients with dementia of Alzheimer type. All patients demonstrated moderately severe dementia at the initial PET scan. Serial PET scans were performed at an interval of 12 to 24 months. Five of the 6 patients showed a deterioration of clinical symptoms at the second scan. The global CMRGlu serially decreased in all patients. An asymmetry of CMRGlu in both the frontal and parietal regions was observed at the initial PET scan, while the direction of asymmetry was preserved at the second PET scan. The ratios (frontal/parietal and parietal/striatum) of CMRGlu showed no interval change. Therefore, CMRGlu was considered to decrease progressively throughout the entire brain in patients with moderately severe dementia of Alzheimer type. (author).

  2. A longitudinal study of CMRGlu in dementia of Alzheimer type

    International Nuclear Information System (INIS)

    Kuwabara, Yasuo; Ichiya, Yuichi; Ichimiya, Atsushi; Sasaki, Masayuki; Akashi, Yuko; Yoshida, Tsuyoshi; Fukumura, Toshimitsu; Masuda, Kouji

    1994-01-01

    We studied the serial changes of CMRGlu in 6 patients with dementia of Alzheimer type. All patients demonstrated moderately severe dementia at the initial PET scan. Serial PET scans were performed at an interval of 12 to 24 months. Five of the 6 patients showed a deterioration of clinical symptoms at the second scan. The global CMRGlu serially decreased in all patients. An asymmetry of CMRGlu in both the frontal and parietal regions was observed at the initial PET scan, while the direction of asymmetry was preserved at the second PET scan. The ratios (frontal/parietal and parietal/striatum) of CMRGlu showed no interval change. Therefore, CMRGlu was considered to decrease progressively throughout the entire brain in patients with moderately severe dementia of Alzheimer type. (author)

  3. Clamping characteristics study on different types of clamping unit

    Energy Technology Data Exchange (ETDEWEB)

    Jiao, Zhiwei; Liu, Haichao; Xie, Pengcheng [College of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing China 100029 (China); Yang, Weimin [College of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing China 100029 (China); State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing China 100029 (China)

    2015-05-22

    Plastic products are becoming more and more widely used in aerospace, IT, digital electronics and many other fields. With the development of technology, the requirement of product precision is getting higher and higher. However, type and working performance of clamping unit play a decisive role in product precision. Clamping characteristics of different types of clamping unit are discussed in this article, which use finite element numerical analysis method through the software ABAQUS to study the clamping uniformity, and detect the clamping force repeatability precision. The result shows that compared with toggled three-platen clamping unit, clamping characteristics of internal circulation two-platen clamping unit are better, for instance, its mold cavity deformation and force that bars and mold parting surface suffered are more uniform, and its clamping uniformity and repeatability precision is also better.

  4. Pain perception studies in tension-type headache.

    Science.gov (United States)

    Bezov, David; Ashina, Sait; Jensen, Rigmor; Bendtsen, Lars

    2011-02-01

    Tension-type headache (TTH) is a disorder with high prevalence and significant impact on society. Understanding of pathophysiology of TTH is paramount for development of effective treatments and prevention of chronification of TTH. Our aim was to review the findings from pain perception studies of pathophysiology of TTH as well as to review the research of pathophysiology of TTH. Pain perception studies such as measurement of muscle tenderness, pain detection thresholds, pain tolerance thresholds, pain response to suprathreshold stimulation, temporal summation and diffuse noxious inhibitory control (DNIC) have played a central role in elucidating the pathophysiology of TTH. It has been demonstrated that continuous nociceptive input from peripheral myofascial structures may induce central sensitization and thereby chronification of the headache. Measurements of pain tolerance thresholds and suprathreshold stimulation have shown presence of generalized hyperalgesia in chronic tension-type headache (CTTH) patients, while DNIC function has been shown to be reduced in CTTH. One imaging study showed loss of gray matter structures involved in pain processing in CTTH patients. Future studies should aim to integrate pain perception and imaging to confirm this finding. Pharmacological studies have shown that drugs like tricyclic anti-depressant amitriptyline and nitric oxide synthase inhibitors can reverse central sensitization and the chronicity of headache. Finally, low frequency electrical stimulation has been shown to rapidly reverse central sensitization and may be a new modality in treatment of CTTH and other chronic pain disorders. © 2010 American Headache Society.

  5. A Preliminary Study Application Clustering System in Acoustic Emission Monitoring

    Directory of Open Access Journals (Sweden)

    Saiful Bahari Nur Amira Afiza

    2017-01-01

    Full Text Available Acoustic Emission (AE is a non-destructive testing known as assessment on damage detection in structural engineering. It also can be used to discriminate the different types of damage occurring in a composite materials. The main problem associated with the data analysis is the discrimination between the different AE sources and analysis of the AE signal in order to identify the most critical damage mechanism. Clustering analysis is a technique in which the set of object are assigned to a group called cluster. The objective of the cluster analysis is to separate a set of data into several classes that reflect the internal structure of data. In this paper was used k-means algorithm for partitioned clustering method, numerous effort have been made to improve the performance of application k-means clustering algorithm. This paper presents a current review on application clustering system in Acoustic Emission.

  6. [Evaluation of blood pressure changes by 24-hours ambulatory blood pressure monitoring (ABPM) in young, normotensive patients with diabetes mellitus type I].

    Science.gov (United States)

    Markuszewski, Leszek; Ruxer, Monika; Szadkowska, Agnieszka; Bodalska, Joanna; Bissinger, Andrzej

    2006-01-01

    The aim of this study was to evaluate usefulness of ambulatory blood pressure monitoring (ABPM) to examine circadian patterns of blood pressure (BP) alterations in young, normotensive patients with type I diabetes mellitus (DM1). We studied 43 patients with DM1 aged 18-28 years, with 9-23 years of DM1, without long-term complications. Control group consisted of 32 healthy persons, matched to the DM1 group. 24h ABPM was performed by a Spacelab 90207 device to obtain daytime (7 AM to 11 PM, readings at 20-min interval) and nighttime (11 PM to 7 AM, readings at 30-min interval) measurements in both groups. During the daytime systolic BP (sBP) and diastolic BP (dBP) were not significantly different from the control group. We noted nighttime sBP and dBP higher in DM1 group: sBE 119.7+/-12.6 mmHg vs. 103.817.1; p = 0.001 l dBP 65.5+/-6.2 vs. 61.5+/-3.1; p = 0.001. The loss of fall in BP ('non-dippers') was more prevalent in DM1 group: 49% vs. 9%; p = 0.003. Pulse pressure (PP) was significantly higher in DM1 patients: 50.9+/-6.9 mmHg vs. 44.8+/-5.6 mmHg; p = 0.0001. ABPM is a useful method in detecting early BP alterations in young normotensive patients with diabetes mellitus type 4 1. Increased PP and suppressed diurnal BP variations could represent a increased risk of cardiovascular complications in young patients with diabetes mellitus type 1.

  7. A Pilot Analysis of the Association Between Types of Monitored Anesthesia Care Drugs and Outcomes in Transfemoral Aortic Valve Replacement Performed Without General Anesthesia.

    Science.gov (United States)

    Chen, Eric Y; Sukumar, Nitin; Dai, Feng; Akhtar, Shamsuddin; Schonberger, Robert B

    2018-04-01

    The types of agents used for monitored anesthesia care (MAC) and their possible differential effects on outcomes have received less study despite increased use over general anesthesia (GA) in transfemoral aortic valve replacements (TAVRs). In this pilot analysis of patients undergoing TAVR using MAC, the authors described the anesthetic agents used and sought to investigate the possible association of anesthetic agent choice with outcomes and the extent to which total weight and time-adjusted doses of anesthetics declined with increasing 10-year age increments. Retrospective observational study. Tertiary teaching hospital. Ninety-three participants scheduled to undergo TAVR, with a primary plan of conscious sedation between November 2014 and June 2016, were included. None. Types of MAC were divided into 4 primary groups, but 2 groups were focused: propofol (n = 39) and dexmedetomidine plus propofol (n = 34). Conversion to GA occurred in 6 participants (6.45%) and was not associated with the type of sedation received. The authors also compared patients who received dexmedetomidine with those who did not in accordance with their a priori analytic plan. There were no associations between the use of dexmedetomidine and postoperative delirium or intensive care unit/hospital length of stay. No significant trends in medication dose adjustments were seen across increasing 10-year age increments. A wide breadth of MAC medications is in use among TAVR patients and does not support differences in outcomes. Despite recommendations to reduce anesthetic drug dosing in the elderly, no significant trends in dose reduction with increasing age were noted. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Environmental monitoring study of linear alkylbenzene sulfonates and insoluble soap in Spanish sewage sludge samples.

    Science.gov (United States)

    Cantarero, Samuel; Zafra-Gómez, Alberto; Ballesteros, Oscar; Navalón, Alberto; Reis, Marco S; Saraiva, Pedro M; Vílchez, José L

    2011-01-01

    In this work we present a monitoring study of linear alkylbenzene sulfonates (LAS) and insoluble soap performed on Spanish sewage sludge samples. This work focuses on finding statistical relations between LAS concentrations and insoluble soap in sewage sludge samples and variables related to wastewater treatment plants such as water hardness, population and treatment type. It is worth to mention that 38 samples, collected from different Spanish regions, were studied. The statistical tool we used was Principal Component Analysis (PC), in order to reduce the number of response variables. The analysis of variance (ANOVA) test and a non-parametric test such as the Kruskal-Wallis test were also studied through the estimation of the p-value (probability of obtaining a test statistic at least as extreme as the one that was actually observed, assuming that the null hypothesis is true) in order to study possible relations between the concentration of both analytes and the rest of variables. We also compared LAS and insoluble soap behaviors. In addition, the results obtained for LAS (mean value) were compared with the limit value proposed by the future Directive entitled "Working Document on Sludge". According to the results, the mean obtained for soap and LAS was 26.49 g kg(-1) and 6.15 g kg(-1) respectively. It is worth noting that LAS mean was significantly higher than the limit value (2.6 g kg(-1)). In addition, LAS and soap concentrations depend largely on water hardness. However, only LAS concentration depends on treatment type.

  9. Study on autonomous decentralized-cooperative function monitoring system

    International Nuclear Information System (INIS)

    Matsuoka, Takeshi; Numano, Masayoshi; Someya, Minoru; Fukuto, Junji; Mitomo, Nobuo; Miyazaki, Keiko; Matsukura, Hiroshi

    1998-01-01

    In this study, on a base of result of a nuclear substrate cross-over study on 'Artificial intelligence for nuclear plant' promoted by 5 years plan since 1989 fiscal year, further developed studies are conducted. The studies are promoted by next 5 years plan on following 6 items: (1) Study on stratified expression technique of autonomous function. (2) Study on expression technique of motion state in decentralized-cooperative function. (3) Study on expression technique of decision making process. (4) Integration to operation control system. (5) Integration to maintenance system. And, (6) Comprehensive evaluation experiment. In 1996 fiscal year, improvement and investigation on automatic classification function of plant state were executed. And, preparation of development environment for expression of robot group motion state was conducted. Furthermore, communication experiment using network to realize integration to operation control and maintenance systems and periodical meetings with other institutes were conducted. (G.K.)

  10. Study of the response of radiation protection monitors in terms of H*(10) in X radiation

    International Nuclear Information System (INIS)

    Nonato, Fernanda B.C.; Carvalho, Valdir S.; Vivolo, Vitor; Caldas, Linda V.E.

    2009-01-01

    The ambient dose equivalent, H * (10), is an operational quantity recommended by the International Commission of radiation Units and Measurements Report 39 for measurements in area monitoring. However, most of the monitoring instruments used in radiation protection in Brazil still use the old quantities exposure rate and absorbed dose rate. Therefore, it is necessary to study how to change the operational quantity to H * (10). In this work, the response of radiation protection monitoring detectors was studied in terms of H * (10) for different energies using standard X-rays (narrow beams) at the Calibration Laboratory of IPEN. (author)

  11. THE EFFECT OF TELE-MONITORING ON EXERCISE TRAINING ADHERENCE, FUNCTIONAL CAPACITY, QUALITY OF LIFE AND GLYCEMIC CONTROL IN PATIENTS WITH TYPE II DIABETES

    Directory of Open Access Journals (Sweden)

    Tracy Marios

    2012-03-01

    Full Text Available We used tele-monitoring to attempt to improve exercise adherence (number of hours of exercise completed, peak VO2, HbA1c% and quality of life in an unsupervised, home based exercise program in people with type II diabetes, a cost analysis was also conducted. Thirty-nine patients with type II diabetes were randomized to tele-monitoring (TELE or control (CON groups. All patients were asked to complete 6 months exercise training and complete an exercise activity diary. The TELE group was instructed to record their exercise heart rates using a monitor and received weekly telephone calls from an exercise physiologist. Six TELE patients and seven CON patients did not complete the 6 month testing. TELE patients completed a mean weekly volume of 138 minutes, moderate intensity exercise, while CON patients completed 58 minutes weekly (p < 0.02. Neither group achieved the American Heart Association statement guideline for weekly exercise volume of 150 minutes. TELE patients improved peak VO2 (5.5 %, but neither group improved HbA1c% or quality of life. The CON group showed a 4.9% reduction in peak VO2. While tele-monitored patients completed more hours of exercise and demonstrated improved peak VO2 compared to controls, the exercise volume completed was insufficient to improve glycemic control. There is the potential via tele-monitoring to enable people with diabetes to meet exercise training guidelines.

  12. Application of an automated patrol-type monitoring system in the reinforced concrete containment vessel at Kashiwazaki-Kariwa Nuclear Power Plant Units 6 and 7

    International Nuclear Information System (INIS)

    Kimoto, T.; Senoh, M.; Hirakawa, H.; Tanaka, K.; Takahashi, M.

    1996-01-01

    An automated patrol-type monitoring system was applied to the first Advanced Boiling Water Reactor (ABWR) plants in the world, Kashiwazaki-Kariwa Nuclear Power Plant Units 6 and 7. The system consists of two robots traveling along monorail and several ITV systems. This monitoring system is used to watch the operating incident of key components of ABWR, such as water leakage from packing in Fine Motion Control Rod Drive (FM-CRD), Reactor Internal Pump (RIP) etc. which are located in the reinforced concrete containment and usually could not be accessible under operation. The traveling robots are equipped with the three kinds of sensors, an infrared camera, a color TV camera and a microphone, and have a capability to inspect the pre-determined inspection points guided by the monorail. This monitoring system is automatically turned on to start inspection at a scheduled time. For Units 6 and 7, this monitoring system, two robots and several ITV systems, can be controlled from one common control desk and one handy-type remote control panel. Since this monitoring system was installed at Kashiwazaki-Kariwa Nuclear Power Plant Units 6 and 7, this system has been operating successfully. (The installation and testing of the system for Unit 6 was finished completely and the testing the system for Unit 7 has been carrying out.) (author)

  13. Initial study and verification of a distributed fiber optic corrosion monitoring system for transportation structures.

    Science.gov (United States)

    2012-07-01

    For this study, a novel optical fiber sensing system was developed and tested for the monitoring of corrosion in : transportation systems. The optical fiber sensing system consists of a reference long period fiber gratings (LPFG) sensor : for corrosi...

  14. A controlled monitoring study of simulated clandestine graves using 3D ground penetrating radar

    CSIR Research Space (South Africa)

    van Schoor, Michael

    2017-06-01

    Full Text Available A controlled three-dimensional ground penetrating radar monitoring study over simulated clandestine graves was conducted near Pretoria, South Africa, in which the detectability of graves as a function of post-burial interval was assessed...

  15. A prospective study of the impact of home monitoring on the family.

    Science.gov (United States)

    Wasserman, A L

    1984-09-01

    Fourteen families whose infants required home monitoring for apnea were followed for approximately 5 years from the initial contact (1977). Each family received at least three psychiatric interviews and two follow-up contacts. Effects on the monitored infant, siblings, and parents were examined in open and semi-structured interviews. At first follow-up (mean of 21 months after monitoring discontinuance), seven of 14 monitored children were characterized as spoiled by parents. By the second follow-up, 2 1/2 years later, nine children showed speech, learning, and motor problems; five of these nine children had required resuscitation during their initial episode. Apnea severity was also related to both duration of monitoring and number of additional psychiatric interviews requested by parents or staff. Of 16 older siblings, 12 had psychological problems reported by their parents at first follow-up; these problems appeared to be largely resolved by the second follow-up, although three children were still having problems that caused parental concern. Monitoring, as well as the apnea itself, caused substantial distress manifested in depression, fatigue, and anxiety in many parents, particularly mothers. However, despite their considerable distress, none of the families discontinued monitoring prematurely. Results of the study indicated that the monitoring experience can be divided into four phases: doubt/acceptance, dependence/frustration, discontinuance, and late effects, with substantial differences in parents' responses occurring only in the last two phases.

  16. Experimental study on engine gas-path component fault monitoring using exhaust gas electrostatic signal

    International Nuclear Information System (INIS)

    Sun, Jianzhong; Zuo, Hongfu; Liu, Pengpeng; Wen, Zhenhua

    2013-01-01

    This paper presents the recent development in engine gas-path components health monitoring using electrostatic sensors in combination with signal-processing techniques. Two ground-based engine electrostatic monitoring experiments are reported and the exhaust gas electrostatic monitoring signal-based fault-detection method is proposed. It is found that the water washing, oil leakage and combustor linear cracking result in an increase in the activity level of the electrostatic monitoring signal, which can be detected by the electrostatic monitoring system. For on-line health monitoring of the gas-path components, a baseline model-based fault-detection method is proposed and the multivariate state estimation technique is used to establish the baseline model for the electrostatic monitoring signal. The method is applied to a data set from a turbo-shaft engine electrostatic monitoring experiment. The results of the case study show that the system with the developed method is capable of detecting the gas-path component fault in an on-line fashion. (paper)

  17. Study on condition monitoring techniques for low voltage electrical cables in nuclear power plants

    International Nuclear Information System (INIS)

    Hirao, Hideo; Sakai, Takeshi; Kajimura, Yuusaku

    2017-01-01

    Low voltage electrical cables installed in nuclear power plants are required to maintain its function in a design basis accident environment and they are qualified to that environment. The cables degrade also in normal operating conditions due to ageing and they must maintain integrity until the end of their qualified life. Demands for the condition monitoring technique for low voltage electrical cables have therefore been increasing as nuclear power plants operate longer. A single perfect method for this purpose is not available yet, but the possibility to use two different types of methods which can complement with each other has been examined. The combination of Fourier Transform Infrared Spectroscopy (FT-IR) and Indenter Modulus (IM) method was found highly effective. FT-IR is a method that determines chemical properties (changes in molecular bindings) of cables by using infrared rays, while IM is a method that determines mechanical properties (changes in hardness) of cables by indenters. Both methods are non-destructive and can be applied in-situ to the same material. Reliability of the evaluation can be assured by applying two different types of measurement principles that complement with each other. In this study, various cable samples with different kinds of insulation material (cross-linked polyethylene, ethylene propylene rubber, silicone rubber etc.) were aged with a special accelerated ageing technique which applies simultaneous thermal and radiation ageing to simulate ageing phenomena in a more realistic manner, and the degree of ageing was evaluated with FT-IR and IM. The evaluation result shows good correlation with ageing time and other ageing properties for most material types and the effectiveness of these methods were demonstrated. (author)

  18. Blood pressure self-monitoring in pregnancy: examining feasibility in a prospective cohort study.

    Science.gov (United States)

    Tucker, Katherine L; Taylor, Kathryn S; Crawford, Carole; Hodgkinson, James A; Bankhead, Clare; Carver, Tricia; Ewers, Elizabeth; Glogowska, Margaret; Greenfield, Sheila M; Ingram, Lucy; Hinton, Lisa; Khan, Khalid S; Locock, Louise; Mackillop, Lucy; McCourt, Christine; Pirie, Alexander M; Stevens, Richard; McManus, Richard J

    2017-12-28

    Raised blood pressure (BP) affects approximately 10% of pregnancies worldwide, and a high proportion of affected women develop pre-eclampsia. This study aimed to evaluate the feasibility of self-monitoring of BP in pregnancy in women at higher risk of pre-eclampsia. This prospective cohort study of self-monitoring BP in pregnancy was carried out in two hospital trusts in Birmingham and Oxford and thirteen primary care practices in Oxfordshire. Eligible women were those defined by the UK National Institute for Health and Care Excellence (NICE) guidelines as at higher risk of pre-eclampsia. A total of 201 participants were recruited between 12 and 16 weeks of pregnancy and were asked to take two BP readings twice daily three times a week through their pregnancy. Primary outcomes were recruitment, retention and persistence of self-monitoring. Study recruitment and retention were analysed with descriptive statistics. Survival analysis was used to evaluate the persistence of self-monitoring and the performance of self-monitoring in the early detection of gestational hypertension, compared to clinic BP monitoring. Secondary outcomes were the mean clinic and self-monitored BP readings and the performance of self-monitoring in the detection of gestational hypertension and pre-eclampsia compared to clinic BP. Of 201 women recruited, 161 (80%) remained in the study at 36 weeks or to the end of their pregnancy, 162 (81%) provided any home readings suitable for analysis, 148 (74%) continued to self-monitor at 20 weeks and 107 (66%) at 36 weeks. Self-monitored readings were similar in value to contemporaneous matched clinic readings for both systolic and diastolic BP. Of the 23 who developed gestational hypertension or pre-eclampsia and self-monitored, 9 (39%) had a raised home BP prior to a raised clinic BP. Self-monitoring of BP in pregnancy is feasible and has potential to be useful in the early detection of gestational hypertensive disorders but maintaining self-monitoring

  19. Evaluation and selection of indicators for land degradation and desertification monitoring: types of degradation, causes, and implications for management.

    Science.gov (United States)

    Kairis, Or; Kosmas, C; Karavitis, Ch; Ritsema, C; Salvati, L; Acikalin, S; Alcalá, M; Alfama, P; Atlhopheng, J; Barrera, J; Belgacem, A; Solé-Benet, A; Brito, J; Chaker, M; Chanda, R; Coelho, C; Darkoh, M; Diamantis, I; Ermolaeva, O; Fassouli, V; Fei, W; Feng, J; Fernandez, F; Ferreira, A; Gokceoglu, C; Gonzalez, D; Gungor, H; Hessel, R; Juying, J; Khatteli, H; Khitrov, N; Kounalaki, A; Laouina, A; Lollino, P; Lopes, M; Magole, L; Medina, L; Mendoza, M; Morais, P; Mulale, K; Ocakoglu, F; Ouessar, M; Ovalle, C; Perez, C; Perkins, J; Pliakas, F; Polemio, M; Pozo, A; Prat, C; Qinke, Y; Ramos, A; Ramos, J; Riquelme, J; Romanenkov, V; Rui, L; Santaloia, F; Sebego, R; Sghaier, M; Silva, N; Sizemskaya, M; Soares, J; Sonmez, H; Taamallah, H; Tezcan, L; Torri, D; Ungaro, F; Valente, S; de Vente, J; Zagal, E; Zeiliguer, A; Zhonging, W; Ziogas, A

    2014-11-01

    Indicator-based approaches are often used to monitor land degradation and desertification from the global to the very local scale. However, there is still little agreement on which indicators may best reflect both status and trends of these phenomena. In this study, various processes of land degradation and desertification have been analyzed in 17 study sites around the world using a wide set of biophysical and socioeconomic indicators. The database described earlier in this issue by Kosmas and others (Environ Manage, 2013) for defining desertification risk was further analyzed to define the most important indicators related to the following degradation processes: water erosion in various land uses, tillage erosion, soil salinization, water stress, forest fires, and overgrazing. A correlation analysis was applied to the selected indicators in order to identify the most important variables contributing to each land degradation process. The analysis indicates that the most important indicators are: (i) rain seasonality affecting water erosion, water stress, and forest fires, (ii) slope gradient affecting water erosion, tillage erosion and water stress, and (iii) water scarcity soil salinization, water stress, and forest fires. Implementation of existing regulations or policies concerned with resources development and environmental sustainability was identified as the most important indicator of land protection.

  20. Monitoring for environmental mutagenesis in wild animals - lessons from human studies

    International Nuclear Information System (INIS)

    Tawn, E.J.

    1999-01-01

    The increasing realisation that environmental monitoring practices need to demonstrate radiological protection of the whole ecosystem has led to suggestions that genotoxic techniques derived from human monitoring of radiation exposure could be applied to other animal species. Human studies have highlighted the need to establish the relationship between exposure, genetic effect and biological consequence so that different study objectives, e.g. hazard identification, dose estimation, risk evaluation, can be addressed by the application of the most appropriate and informative assay. (author)

  1. Security And Privacy Issues in Healthcare Monitoring Systems: A Case Study

    DEFF Research Database (Denmark)

    Handler, Daniel Tolboe; Hauge, Lotte; Spognardi, Angelo

    2017-01-01

    Security and privacy issues are rarely taken into account in automated systems for monitoring elderly people in their home, exposing inhabitants to a number of threats they are usually not aware of. As a case study to expose the major vulnerabilities these systems are exposed to, this paper reviews...... a generic example of automated healthcare monitoring system. The security and privacy issues identified in this case study can be easily generalised and regarded as alarm bells for all the pervasive healthcare professionals....

  2. Comparative study of two modes of gastroesophageal reflux measuring: conventional esophageal pH monitoring and wireless pH monitoring

    Directory of Open Access Journals (Sweden)

    Rimon Sobhi Azzam

    2012-06-01

    Full Text Available CONTEXT: Esophageal pH monitoring is considered to be the gold standard for the diagnosis of gastroesophageal acid reflux. However, this method is very troublesome and considerably limits the patient's routine activities. Wireless pH monitoring was developed to avoid these restrictions. OBJECTIVE: To compare the first 24 hours of the conventional and wireless pH monitoring, positioned 3 cm above the lower esophageal sphincter, in relation to: the occurrence of relevant technical failures, the ability to detect reflux and the ability to correlate the clinical symptoms to reflux. METHODS: Twenty-five patients referred for esophageal pH monitoring and with typical symptoms of gastroesophageal reflux disease were studied prospectively, underwent clinical interview, endoscopy, esophageal manometry and were submitted, with a simultaneous initial period, to 24-hour catheter pH monitoring and 48-hour wireless pH monitoring. RESULTS: Early capsule detachment occurred in one (4% case and there were no technical failures with the catheter pH monitoring (P = 0.463. Percentages of reflux time (total, upright and supine were higher with the wireless pH monitoring (P < 0.05. Pathological gastroesophageal reflux occurred in 16 (64% patients submitted to catheter and in 19 (76% to the capsule (P = 0.355. The symptom index was positive in 12 (48% patients with catheter pH monitoring and in 13 (52% with wireless pH monitoring (P = 0.777. CONCLUSIONS: 1 No significant differences were reported between the two methods of pH monitoring (capsule vs catheter, in regard to relevant technical failures; 2 Wireless pH monitoring detected higher percentages of reflux time than the conventional pH-metry; 3 The two methods of pH monitoring were comparable in diagnosis of pathological gastroesophageal reflux and comparable in correlating the clinical symptoms with the gastroesophageal reflux.

  3. Pain perception studies in tension-type headache

    DEFF Research Database (Denmark)

    Bezov, David; Ashina, Sait; Jensen, Rigmor

    2011-01-01

    Tension-type headache (TTH) is a disorder with high prevalence and significant impact on society. Understanding of pathophysiology of TTH is paramount for development of effective treatments and prevention of chronification of TTH. Our aim was to review the findings from pain perception studies...... of pathophysiology of TTH as well as to review the research of pathophysiology of TTH. Pain perception studies such as measurement of muscle tenderness, pain detection thresholds, pain tolerance thresholds, pain response to suprathreshold stimulation, temporal summation and diffuse noxious inhibitory control (DNIC...... to integrate pain perception and imaging to confirm this finding. Pharmacological studies have shown that drugs like tricyclic anti-depressant amitriptyline and nitric oxide synthase inhibitors can reverse central sensitization and the chronicity of headache. Finally, low frequency electrical stimulation has...

  4. Type 2 diabetes and impaired glucose tolerance are associated with word memory source monitoring recollection deficits but not simple recognition familiarity deficits following water, low glycaemic load, and high glycaemic load breakfasts.

    Science.gov (United States)

    Lamport, Daniel J; Lawton, Clare L; Mansfield, Michael W; Moulin, Chris A J; Dye, Louise

    2014-01-30

    It has been established that type 2 diabetes, and to some extent, impaired glucose tolerance (IGT), are associated with general neuropsychological impairments in episodic memory. However, the effect of abnormalities in glucose metabolism on specific retrieval processes such as source monitoring has not been investigated. The primary aim was to investigate the impact of type 2 diabetes and IGT on simple word recognition (familiarity) and complex source monitoring (recollection). A secondary aim was to examine the effect of acute breakfast glycaemic load manipulations on episodic memory. Data are presented from two separate studies; (i) 24 adults with type 2 diabetes and 12 controls aged 45-75years, (ii) 18 females with IGT and 47 female controls aged 30-50years. Controls were matched for age, IQ, BMI, waist circumference, and depression. Recognition of previously learned words and memory for specifically which list a previously learned word had appeared in (source monitoring) was examined at two test sessions during the morning after consumption of low glycaemic load, high glycaemic load and water breakfasts according to a counterbalanced, crossover design. Type 2 diabetes (pglucose metabolism are not detrimental for global episodic memory processes. This enhances our understanding of how metabolic disorders are associated with memory impairments. © 2013.

  5. Technical assessment study on pool-type LMFBR

    International Nuclear Information System (INIS)

    1986-01-01

    Technical assessment study on pool-type LMFBR was started in 1984 FY, inheriting the products from the Feasibility study, in order to accomplish cost reduction of reactor structure and enhanced structural reliability. This study consists of four major subjects; aseismic design development, component design optimization, high temperature structural design optimization and thermal hydraulics design optimization. In 1985 FY numbers of large model tests and analytical evaluations have been performed based on the prospects obtained in the first year's study. These tests and analyses have produced a lot of findings in each subject. They are concerning; (1) the effect of various building structures and analysis methods on floor response reduction, and data for evaluation of aseismic design concepts and structural integrity to seismic loading in the aseismic design development study. (2) data for evaluation of size reduction of main components in the reactor vessel, and heat transfer data required for structural integrity evaluation in the component design optimization study. (3) data for verification of inelastic analysis method, and assurance of technical applicability of disimilar weld in the high temperature structural design optimization study. (4) the effect of component size and location on thermal hydraulic characteristics, and data of thermal hydraulic similarity in thermal hydraulic design optimization study. This report summarizes the results obtained in 1985 FY. (author)

  6. Cutaneous adverse drug reactions in a tertiary care teaching hospital in India: An intensive monitoring study

    Directory of Open Access Journals (Sweden)

    Sejal Thakkar

    2017-01-01

    Full Text Available Background: The epidemiological data based on intensive monitoring studies are limited for the cutaneous adverse drug reactions (CADRs in terms of incidence. Most of earlier Indian studies focused only on types and causative drugs of CADRs. Aim: The aim of this study is to analyze the CADRs with reference to the incidence, its subgroup analysis, causative drugs, and other clinical characteristics in Indian population. Methodology: Intensive monitoring study was carried out over a period of 3 years in the dermatology outpatient and inpatient department. CADRs due to only systematically administered drugs were considered. The WHO definition for CADR, the WHO causality definitions, modified Schumock and Thornton's criteria for preventability, and International Conference on Harmonisation E2A guidelines for seriousness were considered. Incidence was expressed in percentage and its 95% confidence interval. The incidence was analyzed on basis of characteristics of study population and CADRs. Results: A total of 171 CADRs were observed from 37,623 patients. The CADR incidence was 0.45% (95% CI: 0.39–0.53. The incidence did not significantly differ in different age groups and gender. Commonly observed CADRs were maculopapular rash (23.98%, urticaria (21.64%, and fixed drug eruptions (FDEs (18.13%. Antimicrobials (35.18% and nonsteroidal anti-inflammatory drugs (NSAIDs were suspected in all common CADRs. Anti-infective and NSAIDs were most commonly suspected drugs in overall CADRs, maculopapular rash, urticaria, FDEs, and erythema multiforme. The exact nature of drugs remained inaccessible in one-fourth cases due to use of the over-the-counter self-medications. The incidence of preventable and serious and fatal CADRs was 0.08% (95% CI: 0.05–0.11, 0.04% (95% CI: 0.02–0.06, and 0.003% (95% CI: 0.000–0.001, respectively. Conclusion: Ethnic characteristics should be considered while interpreting incidence from the international studies. The

  7. Electro-resistive bands for non-invasive cardiac and respiration monitoring, a feasibility study

    International Nuclear Information System (INIS)

    Gargiulo, Gaetano D; Breen, Paul P; O’Loughlin, Aiden

    2015-01-01

    Continuous unobtrusive monitoring of tidal volume, particularly for critical care patients (i.e. neonates and patients in intensive care) during sleep studies and during daily activities, is still an unresolved monitoring need. Also a successful monitoring solution is yet to be proposed for continuous non-invasive cardiac stroke volume monitoring that is a novel clinical need. In this paper we present the feasibility study for a wearable, non-invasive, non-contact and unobtrusive sensor (embedded in a standard T-shirt) based on four electro-resistive bands that simultaneously monitors tidal volume and cardiac stroke volume changes. This low power sensor system (requires only 100 mW and accepts a wide power supply range up to ±18 V); thus the sensor can be easily embedded in existing wearable solutions (i.e. Holter monitors). Moreover, being contactless, it can be worn over bandages or electrodes, and as it does not rely over the integrity of the garment to work, it allows practitioners to perform procedures during monitoring. For this preliminary evaluation, one subject has worn the sensor over the period of 24 h (removing it only to shower); the accuracy of the tidal volume tested against a portable spirometer reported a precision of ±10% also during physical activity; accuracy tests for cardiac output (as it may require invasive procedure) have not been carried out in this preliminary trial. (note)

  8. Using a portable sulfide monitor as a motivational tool: a clinical study.

    Science.gov (United States)

    Uppal, Ranjit Singh; Malhotra, Ranjan; Grover, Vishakha; Grover, Deepak

    2012-01-01

    Bad breath has a significant impact on daily life of those who suffer from it. Oral malodor may rank only behind dental caries and periodontal disease as the cause of patient's visit to dentist. An aim of this study was to use a portable sulfide monitor as a motivational tool for encouraging the patients towards the better oral hygiene by correlating the plaque scores with sulfide monitor scores, and comparing the sulfide monitor scores before and after complete prophylaxis and 3 months after patient motivation. 30 patients with chronic periodontitis, having chief complaint of oral malodor participated in this study. At first visit, the plaque scores (P1) and sulfide monitor scores before (BCR1) and after complete oral prophylaxis (BCR2) were taken. Then the patients were motivated towards the better oral hygiene. After 3 months, plaque scores (P2) and sulfide monitor scores (BCR3) were recorded again. It was done using SPSS (student package software for statistical analysis). Paired sample test was performed. Statistically significant reduction in sulfide monitor scores was reported after the complete oral prophylaxis and 3 months after patient motivation. Plaque scores were significantly reduced after a period of 3 months. Plaque scores and breathchecker scores were positively correlated. An intensity of the oral malodor was positively correlated with the plaque scores. The portable sulfide monitor was efficacious in motivating the patients towards the better oral hygiene.

  9. VAMOS: The verification and monitoring options study: Current research options for in-situ monitoring and verification of contaminant remediation and containment within the vadose zone

    International Nuclear Information System (INIS)

    Betsill, J.D.; Gruebel, R.D.

    1995-09-01

    The Verification and Monitoring Options Study Project (VAMOS) was established to identify high-priority options for future vadose-zone environmental research in the areas of in-situ remediation monitoring, post-closure monitoring, and containment emplacement and verification monitoring. VAMOS examined projected needs not currently being met with applied technology in order to develop viable monitoring and verification research options. The study emphasized a compatible systems approach to reinforce the need for utilizing compatible components to provide user friendly site monitoring systems. To identify the needs and research options related to vadose-zone environmental monitoring and verification, a literature search and expert panel forums were conducted. The search included present drivers for environmental monitoring technology, technology applications, and research efforts. The forums included scientific, academic, industry, and regulatory environmental professionals as well as end users of environmental technology. The experts evaluated current and future monitoring and verification needs, methods for meeting these needs, and viable research options and directions. A variety of high-priority technology development, user facility, and technology guidance research options were developed and presented as an outcome of the literature search and expert panel forums

  10. Study of experimentally undetermined neutrino parameters in the light of baryogenesis considering type I and type II Seesaw models

    International Nuclear Information System (INIS)

    Kalita, Rupam

    2017-01-01

    We study to connect all the experimentally undetermined neutrino parameters namely lightest neutrino mass, neutrino CP phases and baryon asymmetry of the Universe within the framework of a model where both type I and type II seesaw mechanisms can contribute to tiny neutrino masses. In this work we study the effects of Dirac and Majorana neutrino phases in the origin of matter-antimatter asymmetry through the mechanism of leptogenesis. Type I seesaw mass matrix considered to a tri-bimaximal (TBM) type neutrino mixing which always gives non zero reactor mixing angle. The type II seesaw mass matrix is then considered in such a way that the necessary deviation from TBM mixing and the best fit values of neutrino parameters can be obtained when both type I and type II seesaw contributions are taken into account. We consider different contribution from type I and type II seesaw mechanism to study the effects of neutrino CP phases in the baryon asymmetry of the universe. We further study to connect all these experimentally undetermined neutrino parameters by considering various contribution of type I and type II seesaw. (author)

  11. Implications for monitoring: study designs and interpretation of results

    International Nuclear Information System (INIS)

    Green, R. H.; Montagna, P.

    1996-01-01

    Two innovative statistical approaches to the interpretation and generalization of the results from the study of long-term environmental impacts of offshore oil and gas exploration and production in the Gulf of Mexico were described. The first of the two methods, the Sediment Quality Triad approach, relies on a test of coherence of responses, whereas the second approach uses small scale spatial heterogeneity of response as evidence of impact. As far as the study design was concerned, it was argued that differing objectives which are demanded of the same study (e.g. generalization about environmental impact of similar platforms versus the spatial pattern of impact around individual platforms) are frequently in conflict. If at all possible, they should be avoided since the conflicting demands tend to compromise the design for both situations. 31 refs., 5 figs

  12. Whole-Home Dehumidifiers: Field-Monitoring Study

    Energy Technology Data Exchange (ETDEWEB)

    Burke, Tom; Willem, Henry; Ni, Chun Chun; Stratton, Hannah; Whitehead, Camilla Dunham; Johnson, Russell

    2014-09-23

    Lawrence Berkeley National Laboratory (LBNL) initiated a WHD field-metering study to expand current knowledge of and obtain data on WHD operation and energy consumption in real-world applications. The field study collected real-time data on WHD energy consumption, along with information regarding housing characteristics, consumer behavior, and various outdoor conditions expected to affect WHD performance and efficiency. Although the metering study collected similar data regarding air conditioner operation, this report discusses only WHDs. The primary objectives of the LBNL field-metering study are to (1) expand knowledge of the configurations, energy consumption profiles, consumer patterns of use (e.g., relative humidity [RH] settings), and environmental parameters of whole-home dehumidification systems; and (2) develop distributions of hours of dehumidifier operation in four operating modes: off, standby, fan-only, and compressor (also called dehumidification mode). Profiling energy consumption entails documenting the power consumption, duration of power consumption in different modes, condensate generation, and properties of output air of an installed system under field conditions of varying inlet air temperature and RH, as well as system configuration. This profiling provides a more detailed and deeper understanding of WHD operation and its complexities. This report describes LBNL’s whole-home dehumidification field-metering study conducted at four homes in Wisconsin and Florida. The initial phase of the WHD field-metering study was conducted on one home in Madison, Wisconsin, from June to December of 2013. During a second phase, three Florida homes were metered from June to October of 2014. This report presents and examines data from the Wisconsin site and from the three Florida sites.

  13. Evaluation of the performance of diagnosis monitors in use in Salvador city: pilot study

    International Nuclear Information System (INIS)

    Garcia, Igor; Geambastiani, Paulo; Ferreira, Mario; Macedo, Eric; Navarro, Marcus; Navarro, Valeria; Pereira, Lara; Jesus, Evandro de; Leite, Handerson Jorge Dourado

    2016-01-01

    Radiologically, the image quality is the accuracy of the representation of the patient's anatomy. Considering the importance of the performance of the monitors to the overall effectiveness of a practice of diagnostic imaging, the objective of this study is to evaluate the performance of diagnostic monitors in use, using the method described in the report 03 of the AAPA and Spanish protocol, using calibrated instrumentation traceable to NIST and to RBC. The results of the monitors evaluated to date show 100% compliance for geometric distortion tests and internal reflection and 0% compliance to the dependence of luminance test. (author)

  14. Study on Remote Monitoring System of Crossing and Spanning Tangent Tower

    Science.gov (United States)

    Chen, Da-bing; Zhang, Nai-long; Zhang, Meng-ge; Wang, Ze-hua; Zhang, Yan

    2017-05-01

    In order to grasp the vibration state of overhead transmission line and ensure the operational security of transmission line, the remote monitoring system of crossing and spanning tangent tower was studied. By use of this system, the displacement, velocity and acceleration of the tower, and the local weather data are collected automatically, displayed on computer of remote monitoring centre through wireless network, real-time collection and transmission of vibration signals are realized. The applying results show that the system is excellent in reliability and accuracy and so on. The system can be used to remote monitoring of transmission tower of UHV power transmission lines and in large spanning areas.

  15. The Early vs. Late Infantile Strabismus Surgery Study: Monitoring Report

    NARCIS (Netherlands)

    H.J. Simonsz (Huib)

    1995-01-01

    textabstractAbstract: The Early vs. Late Infantile Strabismus Surgery Study Group is a group of strabismologists and orthoptists who investigate whether early or late surgery is preferable in infantile strabismus, in a non-randomized, prospective, multi-center trial. Infants between six and 18

  16. Ambulatory blood pressure monitoring in children and adolescents with type-1 diabetes mellitus and its relation to diabetic control and microalbuminuria

    Directory of Open Access Journals (Sweden)

    Mitra Basiratnia

    2012-01-01

    Full Text Available Diabetes mellitus (DM is now considered as the major cause of end-stage kidney failure, and hypertension (HTN is one of the main determinants of progression of renal disease. The aim of this study was to assess the role of blood pressure (BP by ambulatory blood pressure monitoring (ABPM in children and adolescents with type-1 DM and its correlation with micro-albuminuria (MA and diabetic control. Eighty-one patients with type-1 DM (mean age 13 ± 4 years, whose duration of DM was at least two years, were enrolled in this study. The prevalence of HTN based on ABPM was 28.4%, while by casual method it was 32.1%. The pattern of HTN was as follows: mean systolic HTN 27.2%, mean diastolic HTN 11.2%, daytime systolic HTN 17.3%, daytime diastolic HTN 6.2%, night systolic HTN 30.9%, and night diastolic HTN 29.7%. The systolic and diastolic BP loads were 33.4 and 27.2%, respectively. About 70.4% of the patients were non-dippers, 12.4% had masked HTN, and 3.7% had white coat HTN. The pre-valence of MA was 34.6% and that of abnormal HbA 1 c was 82.7%. There was no correlation bet-ween HTN and both MA and HbA 1 c; also, no correlation was found between the duration of dia-betes and HbA 1 c. Moreover, no significant correlation was found between the duration of diabetes and MA (P = 0.080. Despite the high prevalence of abnormal BP profile among diabetic children, prospective longitudinal studies considering the other major risk factors, particularly genetic factors, which have an impact on the progression to diabetic nephropathy, are recommended.

  17. Feasibility study on large pool-type LMFBR

    International Nuclear Information System (INIS)

    1984-01-01

    A feasibility study has been conducted from 1981 FY to 1983 FY, in order to evaluate the feasibility of a large pool-type LMFBR under the Japanese seismic design condition and safety design condition, etc. This study was aimed to establish an original reactor structure concept which meets those design conditions especially required in Japan. In the first year, preceding design concepts had been reviewed and several concepts were originated to be suitable to Japan. For typical two of them being selected by preliminary analysis, test programs were planned. In the second year, more than twenty tests with basic models had been conducted under severe conditions, concurrently analytical approaches were promoted. In the last year, larger model tests were conducted and analytical methods have been verified concerning hydrodynamic effects on structure vibration, thermo-hydraulic behaviours in reactor plena and so on. Finally the reactor structure concepts for a large pool-type LMFBR have been acknowledged to be feasible in Japan. (author)

  18. Experimental aerodynamic study of a car-type bluff body

    Science.gov (United States)

    Conan, Boris; Anthoine, Jérôme; Planquart, Philippe

    2011-05-01

    The Ahmed body is used as a reference model for fundamental studies of car-type bluff body aerodynamics, in particular focused on the influence of the rear slant angle on the drag coefficient. The objectives of the present work are to obtain reliable drag coefficient comparable to the literature and to explain, based on the nature of the flow, its variation when changing the rear slant angle from 10° to 40°. The drag coefficients measured in both an open and a closed test sections differ by less than 0.5% which proves the reliability and reproducibility of the results. The sensitivity of the drag coefficient to some parameters such as the model roughness or the oncoming boundary layer and the lack of precise information on these parameters in the literature could explain the difference observed with the Ahmed drag coefficient data. The various types of measurement techniques used in the study underline their complementarity. The combination of particle image velocimetry and oil visualization provides a deeper understanding of the flow behaviour around the Ahmed body and a physical interpretation of the drag coefficient evolution.

  19. Habitat suitability of patch types: a case study of the Yosemite toad

    Science.gov (United States)

    Liang, Christina T.; Stohlgren, Thomas J.

    2011-01-01

    Understanding patch variability is crucial in understanding the spatial population structure of wildlife species, especially for rare or threatened species. We used a well-tested maximum entropy species distribution model (Maxent) to map the Yosemite toad (Anaxyrus (= Bufo) canorus) in the Sierra Nevada mountains of California. Twenty-six environmental variables were included in the model representing climate, topography, land cover type, and disturbance factors (e.g., distances to agricultural lands, fire perimeters, and timber harvest areas) throughout the historic range of the toad. We then took a novel approach to the study of spatially structured populations by applying the species-environmental matching model separately for 49 consistently occupied sites of the Yosemite toad compared to 27 intermittently occupied sites. We found that the distribution of the entire population was highly predictable (AUC = 0.95±0.03 SD), and associated with low slopes, specific vegetation types (wet meadow, alpine-dwarf shrub, montane chaparral, red fir, and subalpine conifer), and warm temperatures. The consistently occupied sites were also associated with these same factors, and they were also highly predictable (AUC = 0.95±0.05 SD). However, the intermittently occupied sites were associated with distance to fire perimeter, a slightly different response to vegetation types, distance to timber harvests, and a much broader set of aspect classes (AUC = 0.90±0.11 SD). We conclude that many studies of species distributions may benefit by modeling spatially structured populations separately. Modeling and monitoring consistently-occupied sites may provide a realistic snapshot of current species-environment relationships, important climatic and topographic patterns associated with species persistence patterns, and an understanding of the plasticity of the species to respond to varying climate regimes across its range. Meanwhile, modeling and monitoring of widely dispersing

  20. Patterns of type 2 diabetes monitoring in rural towns: How does frequency of HbA1c and lipid testing compare with existing guidelines?

    Science.gov (United States)

    Paul, Christine L; Piterman, Leon; Shaw, Jonathan E; Kirby, Catherine; Barker, Daniel; Robinson, Jennifer; Forshaw, Kristy L; Sikaris, Kenneth A; Bisquera, Alessandra; Sanson-Fisher, Robert W

    2016-12-01

    To indicate levels of monitoring of type 2 diabetes in rural and regional Australia by examining patterns of glycated haemoglobin (HbA1c) and blood lipid testing. Retrospective analysis of pathology services data from twenty regional and rural towns in eastern Australia over 24 months. Of 13 105 individuals who had either a single HbA1c result ≥7.0% (53 mmol mol -1 ); or two or more HbA1c tests within the study period. Frequency of testing of HbA1c and blood lipids (cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol and triglycerides) were compared with guideline recommendations. About 58.3% of patients did not have the recommended 6-monthly HbA1c tests and 30.6% did not have annual lipid testing. For those who did not receive tests at the recommended interval, the mean between-test interval was 10.5 months (95% CI = 7.5-13.5) rather than 6 months for HbA1c testing; and 15.7 (95% CI = 13.3-18.1) months rather than annually for blood lipids. For those with at least one out-of-range test result, 77% of patients failed to receive a follow-up HbA1c test and 86.5% failed to receive a follow-up blood lipid test within the recommended 3 months. Patients less than 50 years of age, living in a more remote area and with poor diabetes control were less likely to have testing at the recommended intervals (P < 0.0001). Although poor diabetes testing is not limited to rural areas, more intensive diabetes monitoring is likely to be needed for patients living in non-metropolitan areas, particularly for some subgroups. © 2016 National Rural Health Alliance Inc.

  1. Delta-He, Ret-He and a New Diagnostic Plot for Differential Diagnosis and Therapy Monitoring of Patients Suffering from Various Disease-Specific Types of Anemia.

    Science.gov (United States)

    Weimann, Andreas; Cremer, Malte; Hernáiz-Driever, Pablo; Zimmermann, Mathias

    2016-01-01

    The present study was aimed to prove the usefulness of a new diagnostic plot (Hema-Plot), illustrating the relationship between the hemoglobin content of reticulocytes (Ret-He) as a marker of functional iron deficiency and the difference between the reticulocyte and erythrocyte hemoglobin content (Delta-He) as a marker of an impaired hemoglobinization of newly formed reticulocytes occurring during inflammatory processes, to differentiate between various disease-specific types of anemia. A complete blood and reticulocyte count was performed on routine EDTA blood samples from 345 patients with and without various disease-specific types of anemia using the Sysmex XN-9000 hematology analyzer: blood healthy newborns (n = 23), blood healthy adults (n = 31), patients suffering from anemia of chronic disease (ACD) due to diverse oncological, chronic inflammatory, or autoimmune diseases (total n = 138) with (n = 65) and without therapy (n = 73), patients with thalassemia and/or hemoglobinopathy (n = 18), patients with iron deficiency anemia (IDA) (n = 35), patients with a combination of ACD and IDA (n = 17), as well as patients suffering from sepsis (total n = 83) with (n = 32) and without therapy (n = 51). The results for Ret-He, Delta-He, and C-reactive protein (CRP) were statistically compared (Mann-Whitney U Test) between the particular patient groups and the diagnostic plots were drawn. Delta-Hemoglobin showed a statistically significant difference between blood healthy newborns and blood healthy adults (p ≤ 0.05), while Ret-He and C-reactive protein did not. In addition, of all three biomarkers only Delta-He showed a statistically significant difference (p ≤ 0.05) between the ACD/IDA and IDA cohort. Delta-He, Ret-He, and CRP showed a statistically significant difference between patient cohorts with and without therapy suffering from ACD, ACD/IDA, and sepsis before and after medical therapy (p ≤ 0.05). The Hema-Plot illustrated the dynamic character of Ret-He and

  2. Using a visual plate waste study to monitor menu performance.

    Science.gov (United States)

    Connors, Priscilla L; Rozell, Sarah B

    2004-01-01

    Two visual plate waste studies were conducted in 1-week phases over a 1-year period in an acute care hospital. A total of 383 trays were evaluated in the first phase and 467 in the second. Food items were ranked for consumption from a low (1) to high (6) score, with a score of 4.0 set as the benchmark denoting a minimum level of acceptable consumption. In the first phase two entrees, four starches, all of the vegetables, sliced white bread, and skim milk scored below the benchmark. As a result six menu items were replaced and one was modified. In the second phase all entrees scored at or above 4.0, as did seven vegetables, and a dinner roll that replaced sliced white bread. Skim milk continued to score below the benchmark. A visual plate waste study assists in benchmarking performance, planning menu changes, and assessing effectiveness.

  3. Valdez air health study - Exposure monitoring and risk assessment

    International Nuclear Information System (INIS)

    Murray, D.R.; Mikkelsen, R.

    1991-01-01

    In Valdez, Alaska there is concern about exposure of the public to benzene and other light hydrocarbons emitted during the loading of tankers from the Trans-Alaska Pipeline. As part of an overall risk assessment, the Valdez Air Health Study, a personal, indoor and outdoor air sampling program patterned after EPA's TEMA Study was designed and carried out. A unique feature of the study is that, during sampling periods, SF 6 tracer was released at the terminal site to represent terminal hydrocarbon emissions to provide a basis for directly quantitating any contribution of terminal emissions to personal exposure. Sixty citizens at Valdez were selected to wear vests containing sampling equipment for 24-hour periods summer and winter. At the homes of 30 of the participants simultaneous indoor and outdoor samples for hydrocarbons and tracer were collected during the period that each participant collected personal air samples. The paper reviews the design of the program, details of the procedures used, results of the August, 1990 program and preliminary results from the February-March, 1991 program

  4. A Comprehensive Study on Technologies of Tyre Monitoring Systems and Possible Energy Solutions

    Directory of Open Access Journals (Sweden)

    Ali E. Kubba

    2014-06-01

    Full Text Available This article presents an overview on the state of the art of Tyre Pressure Monitoring System related technologies. This includes examining the latest pressure sensing methods and comparing different types of pressure transducers, particularly their power consumption and measuring range. Having the aim of this research to investigate possible means to obtain a tyre condition monitoring system (TCMS powered by energy harvesting, various approaches of energy harvesting techniques were evaluated to determine which approach is the most applicable for generating energy within the pneumatic tyre domain and under rolling tyre dynamic conditions. This article starts with an historical review of pneumatic tyre development and demonstrates the reasons and explains the need for using a tyre condition monitoring system. Following this, different tyre pressure measurement approaches are compared in order to determine what type of pressure sensor is best to consider in the research proposal plan. Then possible energy harvesting means inside land vehicle pneumatic tyres are reviewed. Following this, state of the art battery-less tyre pressure monitoring systems developed by individual researchers or by world leading tyre manufacturers are presented. Finally conclusions are drawn based on the reviewed documents cited in this article and a research proposal plan is presented.

  5. PROBLEMS IN VEGETATION MONITORING IN NATURE MANAGEMENT PRACTICE: TWO CASE STUDIES

    Directory of Open Access Journals (Sweden)

    I. DE RONDE

    2007-04-01

    Full Text Available One of the major requirements of the monitoring of vegetation is the comparability of data between years. Therefore, a proper sampling scheme is essential. However, through the years, in nature management practice lots of data collected without a primary monitoring goal. Afterwards, it often seems very valuable to include these older data in the analysis for several reasons. In two examples from military ranges in the Netherlands, two of the problems which can be met with in comparing unequivalent or biased data in monitoring are shown. In the first example, the frequency of grassland species in two sets of relevés is examined. A solution is presented for the overrepresentation of relevés from one or more vegetation types from the first year, based on the area of the vegetation types on the vegetation map of this same year. In the second example, two sequential vegetation maps are compared. A major problem is often the thematic incongruence of sequential vegetation maps. Afterwards, this can only be resolved by upscaling one or both maps. It is concluded that the use of old data for monitoring purposes can be very valuable, but that this often calls for creative data handling, in which GIS and modern computer programmes are very helpful.

  6. Type 1 diabetes genome-wide association studies

    DEFF Research Database (Denmark)

    Pociot, Flemming

    2017-01-01

    Genetic studies have identified >60 loci associated with the risk of developing type 1 diabetes (T1D). The vast majority of these are identified by genome-wide association studies (GWAS) using large case-control cohorts of European ancestry. More than 80% of the heritability of T1D can be explained...... by GWAS data in this population group. However, with few exceptions, their individual contribution to T1D risk is low and understanding their function in disease biology remains a huge challenge. GWAS on its own does not inform us in detail on disease mechanisms, but the combination of GWAS data...... with other omics-data is beginning to advance our understanding of T1D etiology and pathogenesis. Current knowledge supports the notion that genetic variation in both pancreatic β cells and in immune cells is central in mediating T1D risk. Advances, perspectives and limitations of GWAS are discussed...

  7. Feasibility study: Assess the feasibility of siting a monitored retrievable storage facility

    International Nuclear Information System (INIS)

    King, J.W.

    1993-01-01

    The purpose of phase one of this study are: To understand the waste management system and a monitored retrievable storage facility; and to determine whether the applicant has real interest in pursuing the feasibility assessment process. Contents of this report are: Generating electric power; facts about exposure to radiation; handling storage, and transportation techniques; description of a proposed monitored retrievable storage facility; and benefits to be received by host jurisdiction

  8. Feasibility study: Assess the feasibility of siting a monitored retrievable storage facility. Phase 1

    Energy Technology Data Exchange (ETDEWEB)

    King, J.W.

    1993-08-01

    The purpose of phase one of this study are: To understand the waste management system and a monitored retrievable storage facility; and to determine whether the applicant has real interest in pursuing the feasibility assessment process. Contents of this report are: Generating electric power; facts about exposure to radiation; handling storage, and transportation techniques; description of a proposed monitored retrievable storage facility; and benefits to be received by host jurisdiction.

  9. MD 2408: Study of Schottky Monitors for Q' Measurement at Injection

    CERN Document Server

    Tydecks, Tobias; Levens, Tom; Wendt, Manfred; Wenninger, Jorg; CERN. Geneva. ATS Department

    2018-01-01

    The Schottky monitors installed at the LHC enable the detection of Schottky noise of the two circulating proton / ion beams. From Schottky noise, beam parameters like tune, chromaticity, and relative emittance, can be extracted in a non-destructive and purely parasitic method of measurement. The primary goal of this MD was to study the Schottky monitors capability to reliably and accurately determine the beam chromaticities at injection energy. Furthermore, the possibility to track the beam emittance has been investigated.

  10. The effectiveness of continuous subcutaneous insulin pumps with continuous glucose monitoring in outpatient adolescents with type 1 diabetes: A systematic review.

    Science.gov (United States)

    Matsuda, Erin; Brennan, Patricia

    2012-01-01

    The review question is: Are metabolic outcomes improved in outpatient adolescents (aged 13 to 19 years) with type 1 diabetes on a Continuous Subcutaneous Insulin Infusion (CSII) when continuous glucose monitoring is used, compared to self-glucose monitoring alone? Type 1 diabetes is the most common childhood paediatric disease, characterised by impairment of insulin producing βeta-cells in the pancreas. Internationally, there is variation in the incidence of type 1 diabetes in paediatric patients. According to the Center for Disease Control and Prevention (CDC) and the SEARCH for Diabetes in Youth Study Group, the overall incidence rate of this autoimmune disease is 24.3/100,000 in those 19 years of age . Annually, more than 15,000 children and adolescents are diagnosed in the United States (US) . From 1990 to 1999, the World Health Organization (WHO) launched the Multinational Project for Childhood Diabetes (DIAMOND), which was tasked with assessing type 1 diabetes in those 14 years or younger worldwide . Finland was discovered to have the highest age-adjusted incidence at 40.9 cases per 100,000/year. The lowest age-adjusted incidence is in China and Venezuela at 0.1 cases per 100,000/year. Globally, the largest increase in incidence is in those aged 10 to 14 years . This systematic review will focus on adolescent patients with type 1 diabetes, aged 13 to 19 years who manage their diabetes with an insulin pump.Patients with type 1 diabetes mellitus typically present with a history of polydipsia, polyuria, polyphagia, and weight loss . Initial findings include hyperglycemia, glycosuria, and ketones in the blood or urine . In 2009, the International Expert Committee deemed a haemoglobin A1C (glycosylated haemoglobin) of 6.5% or higher to be the standard for diagnosis . The American Diabetes Association (ADA) as well as the International Diabetes Federation and the European Association Study of Diabetes (EASD) accept this measure as the diagnostic tool for diabetes

  11. Condition monitoring: a study on ageing in Inconel 718

    International Nuclear Information System (INIS)

    Acharya, Vidhi; Murthy, G.V.S.

    2015-01-01

    The development of contemporary high temperature materials is needed to enable the successful introduction of cleaner and more efficient next generation power plants. Due to inherent limitations in steels, new high temperature materials must be selected for a change in operating parameters. Inconel-718 is currently considered to be one of the leading materials for use in high temperature applications. Due to its excellent high-temperature mechanical properties, Inconel-718 is believed to be a contender for forged components of Advanced Ultra-Supercritical (A-USC) power plants. The A-USC power plant with steam conditions of 700°C/35 MPa, is expected to have greater efficiency. Thus the microstructural stability and its impact on the mechanical properties of this alloy at elevated temperatures will certainly be a crucial factor that influences the reliability of the power plants. Therefore it is of imminent importance to study the microstructural evolution of components made out of Inconel-718 preferably by Non-destructive methods

  12. TWRS privatization phase 1 monitoring wells engineering study

    International Nuclear Information System (INIS)

    Williams, B.A.; Newcomer, D.R.

    1998-04-01

    This engineering study provides an evaluation of existing wells and boreholes (wells) within the proposed location for the Tank Waste Remediation System (TWRS) Privatization Phase 1 demonstration site. Phase 1 is part of the TWRS program that was established to manage, retrieve, treat, immobilize, and dispose of high-level waste stored in underground tanks at the Hanford Site. This evaluation is to determine which wells will remain active within the demonstration site based on regulatory, programmatic, or other beneficial use requirements. An initial evaluation of wells within the demonstration site was conducted in 1996. However, changes in construction plans and expansion of the demonstration site necessitated a reevaluation and reclassification of the wells that are within the expanded site. Impacted wells include many of those previously evaluated as well as additional wells identified in or near the expansion areas. Thirty-three wells exist within and immediately adjacent to the identified boundary of the proposed demonstration site. The wells identified for decommissioning will be abandoned according to the well decommissioning plan. Future well requirements within the site include replacement wells for those wells impacted by construction activities, replacements for Resource Conservation and Recovery Act of 1976 (RCRA) wells going dry, and a new characterization well installed to support a TWRS Phase 2 site assessment

  13. Experimental study of ERT monitoring ability to measure solute dispersion.

    Science.gov (United States)

    Lekmine, Grégory; Pessel, Marc; Auradou, Harold

    2012-01-01

    This paper reports experimental measurements performed to test the ability of electrical resistivity tomography (ERT) imaging to provide quantitative information about transport parameters in porous media such as the dispersivity α, the mixing front velocity u, and the retardation factor R(f) associated with the sorption or trapping of the tracers in the pore structure. The flow experiments are performed in a homogeneous porous column placed between two vertical set of electrodes. Ionic and dyed tracers are injected from the bottom of the porous media over its full width. Under such condition, the mixing front is homogeneous in the transverse direction and shows an S-shape variation in the flow direction. The transport parameters are inferred from the variation of the concentration curves and are compared with data obtained from video analysis of the dyed tracer front. The variations of the transport parameters obtained from an inversion performed by the Gauss-Newton method applied on smoothness-constrained least-squares are studied in detail. While u and R(f) show a relatively small dependence on the inversion procedure, α is strongly dependent on the choice of the inversion parameters. Comparison with the video observations allows for the optimization of the parameters; these parameters are found to be robust with respect to changes in the flow condition and conductivity contrast. © 2011, The Author(s). Ground Water © 2011, National Ground Water Association.

  14. Webcams for Bird Detection and Monitoring: A Demonstration Study

    Directory of Open Access Journals (Sweden)

    Willem W. Verstraeten

    2010-04-01

    Full Text Available Better insights into bird migration can be a tool for assessing the spread of avian borne infections or ecological/climatologic issues reflected in deviating migration patterns. This paper evaluates whether low budget permanent cameras such as webcams can offer a valuable contribution to the reporting of migratory birds. An experimental design was set up to study the detection capability using objects of different size, color and velocity. The results of the experiment revealed the minimum size, maximum velocity and contrast of the objects required for detection by a standard webcam. Furthermore, a modular processing scheme was proposed to track and follow migratory birds in webcam recordings. Techniques such as motion detection by background subtraction, stereo vision and lens distortion were combined to form the foundation of the bird tracking algorithm. Additional research to integrate webcam networks, however, is needed and future research should enforce the potential of the processing scheme by exploring and testing alternatives of each individual module or processing step.

  15. Awareness during anaesthesia for surgery requiring evoked potential monitoring: A pilot study

    Directory of Open Access Journals (Sweden)

    Pritish J Korula

    2017-01-01

    Full Text Available Background: Evoked potential monitoring such as somatosensory-evoked potential (SSEP or motor-evoked potential (MEP monitoring during surgical procedures in proximity to the spinal cord requires minimising the minimum alveolar concentrations (MACs below the anaesthetic concentrations normally required (1 MAC to prevent interference in amplitude and latency of evoked potentials. This could result in awareness. Our primary objective was to determine the incidence of awareness while administering low MAC inhalational anaesthetics for these unique procedures. The secondary objective was to assess the adequacy of our anaesthetic technique from neurophysiologist′s perspective. Methods: In this prospective observational pilot study, 61 American Society of Anesthesiologists 1 and 2 patients undergoing spinal surgery for whom intraoperative evoked potential monitoring was performed were included; during the maintenance phase, 0.7-0.8 MAC of isoflurane was targeted. We evaluated the intraoperative depth of anaesthesia using a bispectral (BIS index monitor as well as the patients response to surgical stimulus (PRST scoring system. Post-operatively, a modified Bruce questionnaire was used to verify awareness. The adequacy of evoked potential readings was also assessed. Results: Of the 61 patients, no patient had explicit awareness. Intraoperatively, 19 of 61 patients had a BIS value of above sixty at least once, during surgery. There was no correlation with PRST scoring and BIS during surgery. Fifty-four out of 61 patient′s evoked potential readings were deemed ′good′ or ′fair′ for the conduct of electrophysiological monitoring. Conclusions: This pilot study demonstrates that administering low MAC inhalational anaesthetics to facilitate evoked potential monitoring does not result in explicit awareness. However, larger studies are needed to verify this. The conduct of SSEP electrophysiological monitoring was satisfactory with the use of this

  16. Monitored Retrievable Storage conceptual system study: metal storage casks

    International Nuclear Information System (INIS)

    Unterzuber, R.; Cross, T.E.; Krasicki, B.R.

    1983-08-01

    A description of the metal cask storage facility concept is presented with the operations required to handle the spent fuel or high-level wastes and transuranic wastes. A generic Receiving and Handling Facility, provided by PNL, has been used for this study. Modifications to the storage delivery side of the handling facility, necessary to couple the Receiving and Handling Facility with the storage facility, are described. The equipment and support facilities needed for the storage facility are also described. Two separate storage facilities are presented herein: one for all spent fuel storage, and one for storage of high-level waste (HLW) and transuranic waste (TRU). Each facility is described for the capacities and rates defined by PNL in the Concept Technical Performance Criteria and Base Assumptions (see Table 1.3-1). Estimates of costs and time-distributions of expenditures have been developed to construct, operate, and decommission the conceptual MRS facilities in mid-1983 dollars, for the base cases given using the cost categories and percentages provided by PNL. Cost estimates and time-distributions of expenditures have also been developed to expand the facility throughput rate from 1800 MTU to 3000 MTU, and to expand the facility storage capacity from 15,000 MTU to 72,00 MTU. The life cycle cost of the facility for the bounding cases of all spent fuel and all HLW and TRU, using the time-distributions of costs developed above and assuming a two percent per year discount rate, are also presented. 3 references, 16 figures, 18 tables

  17. PISC II: Parametric studies. Monitoring of PISC-II parametric studies in ultrasonic NDT for PWR

    International Nuclear Information System (INIS)

    Toft, M.W.

    1989-09-01

    The CEGB NDT Applications Centre is partipating in the EEC-funded international Programme for the Inspection of Steel Components (PISC) on account of its relevance to the inspection of Sizewell B and future PWRs. This report describes an inspection monitoring exercise undertaken by NDTAC under partial funding from JRC Ispra, at the initiation of the PISC-III Ultrasonic Modelling Group. Experimental studies have been carried out under PISC-II to investigate ultrasonic defect response as a function of various parameters which characterise the inspection situation. Some of these parametric studies are potentially useful for the validation of theoretical models of ultrasonic inspection and are consequently relevant to the work of the PISC-III Modelling Group. The aim of the present exercise was to ensure that data obtained by the various contract organizations participating in the PISC-II Parametric Studies was of high quality, was a complete record of the inspection and would yield valid comparisons with the predictions of theoretical models. The exercise entailed visits by a nominated CEGB observer to 4 European NDT Laboratories at which the parametric studies were in progress; CISE (Milan); UKAEA (Harwell); UKAEA (Risley) and Vincotte (Brussels). This report presents the findings of those visits

  18. Identification of Performance Problems in a Commercial Human Immunodeficiency Virus Type 1 Enzyme Immunoassay by Multiuser External Quality Control Monitoring and Real-Time Data Analysis▿ †

    OpenAIRE

    Kim, J.; Swantee, C.; Lee, B.; Gunning, H.; Chow, A.; Sidaway, F.; Sherlock, C.; Garceau, R.; Dimech, W.; Malloch, L.

    2009-01-01

    In June 2005, a pilot program was implemented in Canadian laboratories to monitor the performance of the Abbott human immunodeficiency virus types 1 and 2 (HIV-1/2) gO enzyme immunoassay (EIA). Two different external quality control (QC) reagents and a “real-time” software analysis program were evaluated. In November 2005, higher-than-expected calibrator rate values in these kits were first reported at the Ontario Ministry of Health (Etobicoke), followed by the Alberta Provincial Public Healt...

  19. Monitoring, genomic study and control of patulin producing fungi in Korean fruits

    International Nuclear Information System (INIS)

    Kim, Dongho; Lim, Sangyong; Joe, Minho; Yun, Hyejung; Kim, Suhyun; Park, Jongchun

    2008-07-01

    This study was intended to apply irradiation technology for the degradation of patulin from apples and apple juices by investigating their physical, mechanical, biological, and pharmacochemical properties in view of potential uses in the bio-industry. The patulin producing fungi was separated from in Korean apples. Totally, 16 morphological types of fungi were isolated from the apples and a patulin producing fungi was identified. The isolated patulin producing fungus was found to a represent species of Penicillium crustosum. The patulin, dissolved in distilled water at a concentration of 50 ppm was practically degraded by the gamma irradiation at the dose of 1.0 kGy, while 33% of the patulin was remained at apple juice. In conclusion, it was suggested that 1 kGy of gamma irradiation (recommended radiation doses for radicidation and/or quarantine in fruits) is effective for the reduction of patulin, but the nutritional elements should be considered because the radio-degradation effects are environment dependant. The effects of a gamma irradiation on the physiochemical and physical characteristics of apple was investigated during a post-irradiation storage at 4 and 25. Gamma irradiation dose not affect stability of the nutritional contents, functional properties and physical characteristics of apples, especially in the condition of a cold storage after a radiation treatment. The degradation condition characteristics of patulin in apple juice and functional properties of corresponding condition were monitored by response surface methodology (RSM)

  20. Monitoring, genomic study and control of patulin producing fungi in Korean fruits

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Dongho; Lim, Sangyong; Joe, Minho; Yun, Hyejung [KAERI, Daejeon (Korea, Republic of); Kim, Suhyun [KBSI, Daejeon (Korea, Republic of); Park, Jongchun [Seonam Univ., Asan (Korea, Republic of)

    2008-07-15

    This study was intended to apply irradiation technology for the degradation of patulin from apples and apple juices by investigating their physical, mechanical, biological, and pharmacochemical properties in view of potential uses in the bio-industry. The patulin producing fungi was separated from in Korean apples. Totally, 16 morphological types of fungi were isolated from the apples and a patulin producing fungi was identified. The isolated patulin producing fungus was found to a represent species of Penicillium crustosum. The patulin, dissolved in distilled water at a concentration of 50 ppm was practically degraded by the gamma irradiation at the dose of 1.0 kGy, while 33% of the patulin was remained at apple juice. In conclusion, it was suggested that 1 kGy of gamma irradiation (recommended radiation doses for radicidation and/or quarantine in fruits) is effective for the reduction of patulin, but the nutritional elements should be considered because the radio-degradation effects are environment dependant. The effects of a gamma irradiation on the physiochemical and physical characteristics of apple was investigated during a post-irradiation storage at 4 and 25. Gamma irradiation dose not affect stability of the nutritional contents, functional properties and physical characteristics of apples, especially in the condition of a cold storage after a radiation treatment. The degradation condition characteristics of patulin in apple juice and functional properties of corresponding condition were monitored by response surface methodology (RSM)

  1. Comparative Study of Different Methods for Soot Sensing and Filter Monitoring in Diesel Exhausts

    Science.gov (United States)

    Feulner, Markus; Hagen, Gunter; Hottner, Kathrin; Redel, Sabrina; Müller, Andreas; Moos, Ralf

    2017-01-01

    Due to increasingly tighter emission limits for diesel and gasoline engines, especially concerning particulate matter emissions, particulate filters are becoming indispensable devices for exhaust gas after treatment. Thereby, for an efficient engine and filter control strategy and a cost-efficient filter design, reliable technologies to determine the soot load of the filters and to measure particulate matter concentrations in the exhaust gas during vehicle operation are highly needed. In this study, different approaches for soot sensing are compared. Measurements were conducted on a dynamometer diesel engine test bench with a diesel particulate filter (DPF). The DPF was monitored by a relatively new microwave-based approach. Simultaneously, a resistive type soot sensor and a Pegasor soot sensing device as a reference system measured the soot concentration exhaust upstream of the DPF. By changing engine parameters, different engine out soot emission rates were set. It was found that the microwave-based signal may not only indicate directly the filter loading, but by a time derivative, the engine out soot emission rate can be deduced. Furthermore, by integrating the measured particulate mass in the exhaust, the soot load of the filter can be determined. In summary, all systems coincide well within certain boundaries and the filter itself can act as a soot sensor. PMID:28218700

  2. Continuous glucose monitoring--a study of the Enlite sensor during hypo- and hyperbaric conditions.

    Science.gov (United States)

    Adolfsson, Peter; Örnhagen, Hans; Eriksson, Bengt M; Cooper, Ken; Jendle, Johan

    2012-06-01

    The performance and accuracy of the Enlite(™) (Medtronic, Inc., Northridge, CA) sensor may be affected by microbubble formation at the electrode surface during hypo- and hyperbaric conditions. The effects of acute pressure changes and of prewetting of sensors were investigated. On Day 1, 24 sensors were inserted on the right side of the abdomen and back in one healthy individual; 12 were prewetted with saline solution, and 12 were inserted dry. On Day 2, this procedure was repeated on the left side. All sensors were attached to an iPro continuous glucose monitoring (CGM) recorder. Hypobaric and hyperbaric tests were conducted in a pressure chamber, with each test lasting 105 min. Plasma glucose values were obtained at 5-min intervals with a HemoCue(®) (Ängelholm, Sweden) model 201 glucose analyzer for comparison with sensor glucose values. Ninety percent of the CGM systems operated during the tests. The mean absolute relative difference was lower during hyperbaric than hypobaric conditions (6.7% vs. 14.9%, Phypobaric but not during hyperbaric conditions. Clarke Error Grid Analysis showed that 100% of the values were found in the A+B region. No differences were found between prewetted and dry sensors. The Enlite sensor performed adequately during acute pressure changes and was more accurate during hyperbaric than hypobaric conditions. Prewetting the sensors did not improve accuracy. Further studies on type 1 diabetes subjects are needed under various pressure conditions.

  3. Comparative Study of Different Methods for Soot Sensing and Filter Monitoring in Diesel Exhausts.

    Science.gov (United States)

    Feulner, Markus; Hagen, Gunter; Hottner, Kathrin; Redel, Sabrina; Müller, Andreas; Moos, Ralf

    2017-02-18

    Due to increasingly tighter emission limits for diesel and gasoline engines, especially concerning particulate matter emissions, particulate filters are becoming indispensable devices for exhaust gas after treatment. Thereby, for an efficient engine and filter control strategy and a cost-efficient filter design, reliable technologies to determine the soot load of the filters and to measure particulate matter concentrations in the exhaust gas during vehicle operation are highly needed. In this study, different approaches for soot sensing are compared. Measurements were conducted on a dynamometer diesel engine test bench with a diesel particulate filter (DPF). The DPF was monitored by a relatively new microwave-based approach. Simultaneously, a resistive type soot sensor and a Pegasor soot sensing device as a reference system measured the soot concentration exhaust upstream of the DPF. By changing engine parameters, different engine out soot emission rates were set. It was found that the microwave-based signal may not only indicate directly the filter loading, but by a time derivative, the engine out soot emission rate can be deduced. Furthermore, by integrating the measured particulate mass in the exhaust, the soot load of the filter can be determined. In summary, all systems coincide well within certain boundaries and the filter itself can act as a soot sensor.

  4. Comparative Study of Different Methods for Soot Sensing and Filter Monitoring in Diesel Exhausts

    Directory of Open Access Journals (Sweden)

    Markus Feulner

    2017-02-01

    Full Text Available Due to increasingly tighter emission limits for diesel and gasoline engines, especially concerning particulate matter emissions, particulate filters are becoming indispensable devices for exhaust gas after treatment. Thereby, for an efficient engine and filter control strategy and a cost-efficient filter design, reliable technologies to determine the soot load of the filters and to measure particulate matter concentrations in the exhaust gas during vehicle operation are highly needed. In this study, different approaches for soot sensing are compared. Measurements were conducted on a dynamometer diesel engine test bench with a diesel particulate filter (DPF. The DPF was monitored by a relatively new microwave-based approach. Simultaneously, a resistive type soot sensor and a Pegasor soot sensing device as a reference system measured the soot concentration exhaust upstream of the DPF. By changing engine parameters, different engine out soot emission rates were set. It was found that the microwave-based signal may not only indicate directly the filter loading, but by a time derivative, the engine out soot emission rate can be deduced. Furthermore, by integrating the measured particulate mass in the exhaust, the soot load of the filter can be determined. In summary, all systems coincide well within certain boundaries and the filter itself can act as a soot sensor.

  5. Platelet indices and glucose control in type 1 and type 2 diabetes mellitus: A case-control study.

    Science.gov (United States)

    Zaccardi, F; Rocca, B; Rizzi, A; Ciminello, A; Teofili, L; Ghirlanda, G; De Stefano, V; Pitocco, D

    2017-10-01

    The relationship between platelet indices and glucose control may differ in type 1 (T1DM) and type 2 (T2DM) diabetes. We aimed to investigate differences in mean platelet volume (MPV), platelet count, and platelet mass between patients with T1DM, T2DM, and healthy controls and to explore associations between these platelet indices and glucose control. A total of 691 T1DM and 459 T2DM patients and 943 control subjects (blood donors) were included. HbA1c was measured in all subjects with diabetes and 36 T1DM patients further underwent 24 h-continuous glucose monitoring to estimate short-term glucose control (glucose mean and standard deviation). Adjusting for age and sex, platelet count was higher and MPV lower in both T1DM and T2DM patients vs control subjects, while platelet mass (MPV × platelet count) resulted higher only in T2DM. Upon further adjustment for HbA1c, differences in platelet count and mass were respectively 19.5 × 10 9 /L (95%CI: 9.8-29.3; p 1) and 101 fL/nL (12-191; p = 0.027) comparing T2DM vs T1DM patients. MPV and platelet count were significantly and differently related in T2DM patients vs both T1DM and control subjects; this difference was maintained also accounting for HbA1c, age, and sex. Platelet mass and the volume-count relationship were significantly related to HbA1c only in T1DM patients. No associations were found between platelet indices and short-term glucose control. By accounting for confounders and glucose control, our data evidenced higher platelet mass and different volume-count kinetics in subjects with T2DM vs T1DM. Long-term glucose control seemed to influence platelet mass and the volume-count relationship only in T1DM subjects. These findings suggest different mechanisms behind platelet formation in T1DM and T2DM patients with long-term glycaemic control being more relevant in T1DM than T2DM. Copyright © 2017 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian

  6. Characteristics of an environmentally monitored prolonged type 2 vaccine derived poliovirus shedding episode that stopped without intervention.

    Directory of Open Access Journals (Sweden)

    Tapani Hovi

    Full Text Available Vaccine derived poliovirus (VDPV type 2 strains strongly divergent from the corresponding vaccine strain, Sabin 2, were repeatedly isolated from sewage in Slovakia over a period of 22 months in 2003-2005. Cell cultures of stool specimens from known immune deficient patients and from an identified putative source population of 500 people failed to identify the potential excretor(s of the virus. The occurrence of VDPV in sewage stopped without any intervention. No paralytic cases were reported in Slovakia during the episode. According to a GenBank search and similarity plotting-analysis, the closest known relative of the first isolate PV2/03/SVK/E783 through all main sections of the genome was the type 2 poliovirus Sabin strain, with nucleotide identities in 5'UTR, P1, P2, P3, and 3'UTR parts of the genome of 88.6, 85.9, 87.3, 88.5, and 94.0 percent, respectively. Phenotypic properties of selected Slovakian aVDPV strains resembled those of VDPV strains isolated from immune deficient individuals with prolonged PV infection (iVDPV, including antigenic changes and moderate neurovirulence in the transgenic mouse model. One hundred and two unique VP1 coding sequences were determined from VDPV strains isolated from 34 sewage specimens. Nucleotide differences from Sabin 2 in the VP1 coding region ranged from 12.5 to 15.6 percent, and reached a maximum of 9.6 percent between the VDPV strains under study. Most of the nucleotide substitutions were synonymous but as many as 93 amino acid positions out of 301 in VP1 showed substitutions. We conclude that (1 individuals with prolonged poliovirus infection are not as rare as suggested by the studies on immune deficient patients known to the health care systems and (2 genetic divergence of VDPV strains may remain extensive during years long replication in humans.

  7. Characteristics of an Environmentally Monitored Prolonged Type 2 Vaccine Derived Poliovirus Shedding Episode that Stopped without Intervention

    Science.gov (United States)

    Hovi, Tapani; Paananen, Anja; Blomqvist, Soile; Savolainen-Kopra, Carita; Al-Hello, Haider; Smura, Teemu; Shimizu, Hiroyuki; Nadova, Katarina; Sobotova, Zdenka; Gavrilin, Eugene; Roivainen, Merja

    2013-01-01

    Vaccine derived poliovirus (VDPV) type 2 strains strongly divergent from the corresponding vaccine strain, Sabin 2, were repeatedly isolated from sewage in Slovakia over a period of 22 months in 2003–2005. Cell cultures of stool specimens from known immune deficient patients and from an identified putative source population of 500 people failed to identify the potential excretor(s) of the virus. The occurrence of VDPV in sewage stopped without any intervention. No paralytic cases were reported in Slovakia during the episode. According to a GenBank search and similarity plotting-analysis, the closest known relative of the first isolate PV2/03/SVK/E783 through all main sections of the genome was the type 2 poliovirus Sabin strain, with nucleotide identities in 5′UTR, P1, P2, P3, and 3′UTR parts of the genome of 88.6, 85.9, 87.3, 88.5, and 94.0 percent, respectively. Phenotypic properties of selected Slovakian aVDPV strains resembled those of VDPV strains isolated from immune deficient individuals with prolonged PV infection (iVDPV), including antigenic changes and moderate neurovirulence in the transgenic mouse model. One hundred and two unique VP1 coding sequences were determined from VDPV strains isolated from 34 sewage specimens. Nucleotide differences from Sabin 2 in the VP1 coding region ranged from 12.5 to 15.6 percent, and reached a maximum of 9.6 percent between the VDPV strains under study. Most of the nucleotide substitutions were synonymous but as many as 93 amino acid positions out of 301 in VP1 showed substitutions. We conclude that (1) individuals with prolonged poliovirus infection are not as rare as suggested by the studies on immune deficient patients known to the health care systems and (2) genetic divergence of VDPV strains may remain extensive during years long replication in humans. PMID:23935826

  8. QRAC-the-Code: a comprehension monitoring strategy for middle school social studies textbooks.

    Science.gov (United States)

    Berkeley, Sheri; Riccomini, Paul J

    2013-01-01

    Requirements for reading and ascertaining information from text increase as students advance through the educational system, especially in content-rich classes; hence, monitoring comprehension is especially important. However, this is a particularly challenging skill for many students who struggle with reading comprehension, including students with learning disabilities. A randomized pre-post experimental design was employed to investigate the effectiveness of a comprehension monitoring strategy (QRAC-the-Code) for improving the reading comprehension of 323 students in grades 6 and 7 in inclusive social studies classes. Findings indicated that both general education students and students with learning disabilities who were taught a simple comprehension monitoring strategy improved their comprehension of textbook content compared to students who read independently and noted important points. In addition, students in the comprehension monitoring condition reported using more reading strategies after the intervention. Implications for research and practice are discussed.

  9. Studies on simulated nuclear waste of mixed solvent type

    International Nuclear Information System (INIS)

    Aggarwal, S.

    1989-09-01

    Caesium 137, strontium 90 and ruthenium 106 are among the longest lived fission products present in reprocessing wastes and are therefore considered to be a long term hazard to the environment. A method for removal of 137-Cs, 90-Sr and 106-Ru from the nuclear waste is by ion-exchange and sorption. Radiochemical methods were employed to investigate the uptake of 137-Cs, 90-Sr and 106-Ru by synthetic type A, X, Y, zeolites and by mordenite and clinoptilolite. The solvents employed were tributylphosphate (TBP) and kerosene (OK). The dependence of the exchange process on time was studied at room temperature. The exchange equilibrium was strongly dependent on time during the first hour but then attained equilibrium. It was also noted that the distribution coefficient (Kd) values for 137-Cs were higher than those for 90-Sr which were higher than those for 106-Ru. Thus the order of extraction was: 137-Cs > 90-Sr > 106-Ru. Ethanol was also used as the solvent to see the effect on the Kds by varying the amount of water present, i.e. from 0% water to 10% water. It was observed that the Kd increased with an increase in water content. The effect of pH and different ratios of TBP:OK were also studied. There was no relationship between the Kds and the different ratios. Some work was also done on the adsorption of 137-Cs on cements and cement phases. The sorption of 137-Cs on to all types of cements was low. (author)

  10. Research plan for integrated ecosystem and pollutant monitoring at remote wilderness study sites

    International Nuclear Information System (INIS)

    Bruns, D.A.; Wiersma, G.B.

    1988-03-01

    This research plan outlines an approach to the measurement of pollutants and ecosystem parameters at remote, high-elevation, wilderness study sites. A multimedia, systems approach to environmental monitoring is emphasized. The primary purpose of the research is to apply and field test a technical report entitled ''Guidelines for measuring the physical, chemical, and biological condition of wilderness ecosystems.'' This document intended to provide Federal Land Managers with information to establish environmental monitoring programs in wilderness areas. To date, this monitoring document has yet to be evaluated under rigorous field conditions at a remote, high-elevation Rocky Mountain site. For the purpose of field testing approaches to monitoring of pollutants and ecosystems in remote, wilderness areas, evaluation criteria were developed. These include useability, cost-effectiveness, data variability, alternative approaches, ecosystems conceptual approach, and quality assurance. Both the Forest Service and INEL environmental monitoring techniques will be evaluated with these criteria. Another objective of this research plan is to obtain an integrated data base on pollutants and ecosystem structure and function at a remote study site. The methods tested in this project will be used to acquire these data from a systems approach. This includes multimedia monitoring of air and water quality, soils, and forest, stream, and lake ecosystems. 71 refs., 1 fig., 9 tabs

  11. Ethical issues in using Twitter for population-level depression monitoring: a qualitative study.

    Science.gov (United States)

    Mikal, Jude; Hurst, Samantha; Conway, Mike

    2016-04-14

    Recently, significant research effort has focused on using Twitter (and other social media) to investigate mental health at the population-level. While there has been influential work in developing ethical guidelines for Internet discussion forum-based research in public health, there is currently limited work focused on addressing ethical problems in Twitter-based public health research, and less still that considers these issues from users' own perspectives. In this work, we aim to investigate public attitudes towards utilizing public domain Twitter data for population-level mental health monitoring using a qualitative methodology. The study explores user perspectives in a series of five, 2-h focus group interviews. Following a semi-structured protocol, 26 Twitter users with and without a diagnosed history of depression discussed general Twitter use, along with privacy expectations, and ethical issues in using social media for health monitoring, with a particular focus on mental health monitoring. Transcripts were then transcribed, redacted, and coded using a constant comparative approach. While participants expressed a wide range of opinions, there was an overall trend towards a relatively positive view of using public domain Twitter data as a resource for population level mental health monitoring, provided that results are appropriately aggregated. Results are divided into five sections: (1) a profile of respondents' Twitter use patterns and use variability; (2) users' privacy expectations, including expectations regarding data reach and permanence; (3) attitudes towards social media based population-level health monitoring in general, and attitudes towards mental health monitoring in particular; (4) attitudes towards individual versus population-level health monitoring; and (5) users' own recommendations for the appropriate regulation of population-level mental health monitoring. Focus group data reveal a wide range of attitudes towards the use of public

  12. U.S. Geological Survey geohydrologic studies and monitoring at the Idaho National Laboratory, southeastern Idaho

    Science.gov (United States)

    Bartholomay, Roy C.

    2017-09-14

    BackgroundThe U.S. Geological Survey (USGS) geohydrologic studies and monitoring at the Idaho National Laboratory (INL) is an ongoing, long-term program. This program, which began in 1949, includes hydrologic monitoring networks and investigative studies that describe the effects of waste disposal on water contained in the eastern Snake River Plain (ESRP) aquifer and the availability of water for long-term consumptive and industrial use. Interpretive reports documenting study findings are available to the U.S. Department of Energy (DOE) and its contractors; other Federal, State, and local agencies; private firms; and the public at https://id.water.usgs.gov/INL/Pubs/index.html. Information contained within these reports is crucial to the management and use of the aquifer by the INL and the State of Idaho. USGS geohydrologic studies and monitoring are done in cooperation with the DOE Idaho Operations Office.

  13. Quality control of CT systems by automated monitoring of key performance indicators: a two-year study.

    Science.gov (United States)

    Nowik, Patrik; Bujila, Robert; Poludniowski, Gavin; Fransson, Annette

    2015-07-08

    The purpose of this study was to develop a method of performing routine periodical quality controls (QC) of CT systems by automatically analyzing key performance indicators (KPIs), obtainable from images of manufacturers' quality assurance (QA) phantoms. A KPI pertains to a measurable or determinable QC parameter that is influenced by other underlying fundamental QC parameters. The established KPIs are based on relationships between existing QC parameters used in the annual testing program of CT scanners at the Karolinska University Hospital in Stockholm, Sweden. The KPIs include positioning, image noise, uniformity, homogeneity, the CT number of water, and the CT number of air. An application (MonitorCT) was developed to automatically evaluate phantom images in terms of the established KPIs. The developed methodology has been used for two years in clinical routine, where CT technologists perform daily scans of the manufacturer's QA phantom and automatically send the images to MonitorCT for KPI evaluation. In the cases where results were out of tolerance, actions could be initiated in less than 10 min. 900 QC scans from two CT scanners have been collected and analyzed over the two-year period that MonitorCT has been active. Two types of errors have been registered in this period: a ring artifact was discovered with the image noise test, and a calibration error was detected multiple times with the CT number test. In both cases, results were outside the tolerances defined for MonitorCT, as well as by the vendor. Automated monitoring of KPIs is a powerful tool that can be used to supplement established QC methodologies. Medical physicists and other professionals concerned with the performance of a CT system will, using such methods, have access to comprehensive data on the current and historical (trend) status of the system such that swift actions can be taken in order to ensure the quality of the CT examinations, patient safety, and minimal disruption of service.

  14. Mendelian randomization study of B-type natriuretic peptide and type 2 diabetes: evidence of causal association from population studies.

    Directory of Open Access Journals (Sweden)

    Roman Pfister

    2011-10-01

    Full Text Available Genetic and epidemiological evidence suggests an inverse association between B-type natriuretic peptide (BNP levels in blood and risk of type 2 diabetes (T2D, but the prospective association of BNP with T2D is uncertain, and it is unclear whether the association is confounded.We analysed the association between levels of the N-terminal fragment of pro-BNP (NT-pro-BNP in blood and risk of incident T2D in a prospective case-cohort study and genotyped the variant rs198389 within the BNP locus in three T2D case-control studies. We combined our results with existing data in a meta-analysis of 11 case-control studies. Using a Mendelian randomization approach, we compared the observed association between rs198389 and T2D to that expected from the NT-pro-BNP level to T2D association and the NT-pro-BNP difference per C allele of rs198389. In participants of our case-cohort study who were free of T2D and cardiovascular disease at baseline, we observed a 21% (95% CI 3%-36% decreased risk of incident T2D per one standard deviation (SD higher log-transformed NT-pro-BNP levels in analysis adjusted for age, sex, body mass index, systolic blood pressure, smoking, family history of T2D, history of hypertension, and levels of triglycerides, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol. The association between rs198389 and T2D observed in case-control studies (odds ratio = 0.94 per C allele, 95% CI 0.91-0.97 was similar to that expected (0.96, 0.93-0.98 based on the pooled estimate for the log-NT-pro-BNP level to T2D association derived from a meta-analysis of our study and published data (hazard ratio = 0.82 per SD, 0.74-0.90 and the difference in NT-pro-BNP levels (0.22 SD, 0.15-0.29 per C allele of rs198389. No significant associations were observed between the rs198389 genotype and potential confounders.Our results provide evidence for a potential causal role of the BNP system in the aetiology of T2D. Further studies

  15. [Correlation study between obesity and dawn phenomenon in patients with type 2 diabetes].

    Science.gov (United States)

    Guo, Zhenhong; Xu, Jie; Wang, Jingyu; Han, Fei; Zhang, Yi; Yang, X iaoyun; Yang, Shaohua; Chang, Bai; Yang, Juhong; Shan, Chunyan; Chen, Liming; Chang, Baocheng; Xu, Yanguang

    2016-01-01

    To investigate the correlation between the frequency of dawn phenomenon and obesity in patients with type 2 diabetes. This study was conducted in 98 patients with type 2 diabetes admitted to the Metabolic Disease Hospital of Tianjin Medical University from 2011 to 2014. The subjects were divided into 3 groups according to BMI: the normal weight (BMI 18.5-23.9 kg/m(2), n = 30), the overweight(BMI 24-27.9 kg/m(2), n = 33)and the obesity (BMI ≥ 28.0 kg/m(2), n = 35). All participants underwent continuous glucose monitoring for 72 h. Fasting plasma glucose(FPG), insulin and C-peptide were tested. Frequency of dawn phenomenon among the 3 groups was calculated, and the correlations between dawn phenomenon and its related factors were analyzed. The frequency of dawn phenomenon in type 2 diabetes increased with the increase of BMI in the 3 groups (P obesity groups, respectively. The dawn phenomenon was positively correlated with BMI (r = 0.424, P fasting C-peptide (r = 0.254, P 0.05). The dawn phenomenon is closely associated with obesity and insulin resistance. The frequency of dawn phenomenon increases with BMI.

  16. Transport studies in p-type double quantum well samples

    International Nuclear Information System (INIS)

    Hyndman, R.J.

    2000-01-01

    The motivation for the study of double quantum well samples is that the extra spatial degree of freedom can modify the ground state energies of the system, leading to new and interesting many body effects. Electron bi-layers have been widely studied but the work presented here is the first systematic study of transport properties of a p-type, double quantum well system. The samples, grown on the 311 plane, consisted of two 100A GaAs wells separated by a 30A AlAs barrier. The thin barrier in our structures, gives rise to very strong inter-layer Coulombic interactions but in contrast to electron double quantum well samples, tunnelling between the two wells is very weak. This is due to the large effective mass of holes compared with electrons. It is possible to accurately control the total density of a sample and the relative occupancy of each well using front and back gates. A systematic study of the magnetoresistance properties of the p-type bi-layers, was carried out at low temperatures and in high magnetic fields, for samples covering a range of densities. Considerable care was required to obtain reliable results as the samples were extremely susceptible to electrical shock and were prone to drift in density slowly over time. With balanced wells, the very low tunnelling in the p-type bi-layer leads to a complete absence of all odd integers in both resistance and thermopower except for the v=1 state, ( v 1/2 in each layer) where v is the total Landau level filling factor. Unlike other FQHE features the v=1 state strengthens with increased density as inter-layer interactions increase in strength over intra-layer interactions. The state is also destroyed at a critical temperature, which is much lower than the measured activation temperature. This is taken as evidence for a finite temperature phase transition predicted for the bi-layer v=1. From the experimental observations, we construct a phase diagram for the state, which agree closely with theoretical predictions

  17. Identifying professionals' needs in integrating electronic pain monitoring in community palliative care services: An interview study.

    Science.gov (United States)

    Taylor, Sally; Allsop, Matthew J; Bekker, Hilary L; Bennett, Michael I; Bewick, Bridgette M

    2017-07-01

    Poor pain assessment is a barrier to effective pain control. There is growing interest internationally in the development and implementation of remote monitoring technologies to enhance assessment in cancer and chronic disease contexts. Findings describe the development and testing of pain monitoring systems, but research identifying the needs of health professionals to implement routine monitoring systems within clinical practice is limited. To inform the development and implementation strategy of an electronic pain monitoring system, PainCheck, by understanding palliative care professionals' needs when integrating PainCheck into routine clinical practice. Qualitative study using face-to-face interviews. Data were analysed using framework analysis Setting/participants: Purposive sample of health professionals managing the palliative care of patients living in the community Results: A total of 15 interviews with health professionals took place. Three meta-themes emerged from the data: (1) uncertainties about integration of PainCheck and changes to current practice, (2) appraisal of current practice and (3) pain management is everybody's responsibility Conclusion: Even the most sceptical of health professionals could see the potential benefits of implementing an electronic patient-reported pain monitoring system. Health professionals have reservations about how PainCheck would work in practice. For optimal use, PainCheck needs embedding within existing electronic health records. Electronic pain monitoring systems have the potential to enable professionals to support patients' pain management more effectively but only when barriers to implementation are appropriately identified and addressed.

  18. Personality types and Facebook advertising::an exploratory study

    OpenAIRE

    Clark, Lillian; Calli, Levent

    2014-01-01

    The Five-Factor Model of personality types has been utilized by a number of computer science and psychology academics as a framework to explore aspects of internet adoption and, more recently, social media adoption and behaviours. While the use of personality type models in research has been less popular with marketing academics, the Five-Factor Model has been used to predict the emotional appeal of advertising based on personality types and potentially to provide guidelines for tailoring adv...

  19. Follow up study of Alzheimer's type dementia with computed tomography

    International Nuclear Information System (INIS)

    Hirata, Nobuhide

    1987-01-01

    In 54 patients who were diagnosed as having Alzheimer's type dementia based on the Diagnostic and Statistical Manual of Mental Disorders, III, cranial computed tomography (CT) scans were obtained before and after their follow-up study ranging from 6 to 24 months (mean 15.4 +- 4.7 months). Cerebrospinal percentage and CT density in various regions of interest were examined. Six patients died during the study. Comparison of the group of the deceased (Group I) with the group of survivors (Group II) revealed: (1) there was no difference in average age and the degree of mental disorder at first presentation; (2) Group I had decreased activities of daily living; and (3) CT density was significantly decreased in the bilateral lateral and frontal lobes in Group I. As for Group II, decreased CT numbers were noticeable during the follow-up period in the frontal lobe, parietal lobe, and caudate nucleus in the group evaluated as aggravated, as compared with the group evaluated as unchanged. (Namekawa, K.)

  20. Study of homogeneous fuel cells type 10 x 10

    International Nuclear Information System (INIS)

    Montes, J.L.; Perusquia, R.; Ortiz, J.J.; Francois, J.L.; Marquez, C.M.

    2005-01-01

    At the moment in the National Institute of Nuclear Research (ININ) are carried out studies with the purpose of to establish a methodology that allows to carry out the neutron design of fuel cells of type 10 x 10. During the initial stage of the process of cells design, starting from the data that have to do with the planned energy demand it requires to be estimated the average value of the enrichment in U 235 w/o of the one assemble. The experience has shown that the accuracy that is achieved in this estimate it depends, among other factors, of the information (e.g. concentrations of U 235 and Gd 2 O 3 ) of the cells that its are disposed in that moment. For what we consider convenient to enlarge the available information by means of a series of calculations of cell physics; and to the one same time some aspects can be studied on the parameters that define the characteristics of a fuel cell. In this work the effect of the presence of different distributions of the concentrations of the fissile material is analyzed and of burnup poisons on the reactivity parameters of the cell as well as in the peak factor of local power (LPPF-Local Power Peaking Factor). (Author)

  1. Ovulation monitoring and fertility knowledge: Their relationship to fertility experience in a cross-sectional study.

    Science.gov (United States)

    Righarts, Antoinette; Dickson, Nigel P; Parkin, Lianne; Gillett, Wayne R

    2017-08-01

    Various aspects of fertility knowledge, including the timing of the fertile window, have consistently been found to be poor. Limited evidence also suggests ovulation monitoring to time intercourse could be common. However, there have been no studies that compare these two aspects of fertility and women's fertility/infertility experiences. To examine the frequency of ovulation monitoring and its relationship with fertility knowledge and experience. A cross-sectional study of women aged 25-50 years resident in southern New Zealand was undertaken in 2011. Randomly selected women were asked to complete a fertility questionnaire. Outcome prevalence measures were calculated with 95% confidence intervals (CI) and associations investigated using χ 2 tests and Poisson regression. Ovulation monitoring was common, having ever been undertaken by 31.4% (95% CI: 28.5-34.3%) of the 1034 participants. However, knowledge was poor, particularly regarding the fertile window. More women who had ever monitored ovulation correctly identified the fertile window, although the proportion was still very low (18.4 vs 13.1% in those who had not, P = 0.027). Regression modelling showed ovulation monitoring was independently associated with seeking medical help to conceive, education and fertility experience, but not with knowledge. This study confirms ovulation monitoring was commonly undertaken. However, many women, including those who had monitored their ovulation, had poor fertility knowledge and failed to identify the fertile window. Poor fertility knowledge needs to be addressed, especially among women intending to conceive. © 2017 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

  2. Effects of Information Feedback and Self-Administered Consequences on Self-Monitoring Study Behavior

    Science.gov (United States)

    Richards, C. Steven; And Others

    1976-01-01

    The hypotheses tested among college students (N=87) concerned about study habits were: (a) self-monitoring changes study behavior; (b) information feedback accounts for some of this change; and (c) this change can be enhanced by manipulating the quantity and quality of information feedback and self-administered consequences associated with…

  3. Retrospective study of diseases and associated pneumonia type ...

    African Journals Online (AJOL)

    ADEYEYE

    2014-09-05

    Sep 5, 2014 ... The causes and types of pneumonia in dogs have not been accorded due attention in Nigeria. It is imperative to ... records while the specific type of pneumonia was by histopathology of selected lungs tissues, using standard techniques. .... compromised immunity or those associated with stress due to early ...

  4. Retrospective study of diseases and associated pneumonia type ...

    African Journals Online (AJOL)

    The causes and types of pneumonia in dogs have not been accorded due attention in Nigeria. It is imperative to investigate the incidence and type of pneumonia commonly observed during post-mortem at the Department of Veterinary Pathology arm of the Veterinary Teaching Hospital, Ibadan, Nigeria. This investigation ...

  5. Gastroesophageal reflux: comparison of barium studies with 24-h pH monitoring

    International Nuclear Information System (INIS)

    Pan, John J.; Levine, Marc S.; Redfern, Regina O.; Rubesin, Stephen E.; Laufer, Igor; Katzka, David A.

    2003-01-01

    Objective: To determine the correlation between massive gastroesophageal reflux (GER) on barium studies and pathologic acid reflux on 24-h pH monitoring. Methods: A search of hospital records from January 1997 to January 2001 revealed 28 patients who underwent both barium studies and 24-h pH monitoring. The radiologic reports were reviewed to determine the presence and degree of GER. Patients with reflux to or above the thoracic inlet either spontaneously or with provocative maneuvers in the recumbent position were classified as having massive reflux, whereas the remaining patients with reflux below the thoracic inlet or no reflux comprised the control group. The pH monitoring reports were also reviewed to determine if pathologic acid reflux was present in the recumbent position. The findings on these studies were then compared to determine the frequency of pathologic acid reflux in the recumbent position on pH monitoring in patients with massive reflux on barium studies compared with the control group. Results: Massive GER was observed on barium studies in 11 (39%) of the 28 patients and reflux below the thoracic inlet or no reflux in the remaining 17 patients (61%) who comprised the control group. All 11 patients (100%) with massive reflux on barium studies had pathologic acid reflux on pH monitoring in the recumbent position compared with six (35%) of 17 patients in the control group (P=0.0009). The pH in the distal esophagus on pH monitoring was less than 4.0 for 13.1% of the recumbent period for patients with massive GER on barium studies compared with 6.2% of the recumbent period for the control group (P=0.0076). Conclusion: Although 24-h pH monitoring remains the gold standard for the detection of GER, our experience suggests that patients with massive reflux on barium studies are so likely to have pathologic acid reflux in the recumbent position that these individuals can be further evaluated and treated for their gastroesophageal reflux disease (GERD

  6. Gastroesophageal reflux: comparison of barium studies with 24-h pH monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Pan, John J.; Levine, Marc S. E-mail: levine@oasis.rad.upenn.edu; Redfern, Regina O.; Rubesin, Stephen E.; Laufer, Igor; Katzka, David A

    2003-08-01

    Objective: To determine the correlation between massive gastroesophageal reflux (GER) on barium studies and pathologic acid reflux on 24-h pH monitoring. Methods: A search of hospital records from January 1997 to January 2001 revealed 28 patients who underwent both barium studies and 24-h pH monitoring. The radiologic reports were reviewed to determine the presence and degree of GER. Patients with reflux to or above the thoracic inlet either spontaneously or with provocative maneuvers in the recumbent position were classified as having massive reflux, whereas the remaining patients with reflux below the thoracic inlet or no reflux comprised the control group. The pH monitoring reports were also reviewed to determine if pathologic acid reflux was present in the recumbent position. The findings on these studies were then compared to determine the frequency of pathologic acid reflux in the recumbent position on pH monitoring in patients with massive reflux on barium studies compared with the control group. Results: Massive GER was observed on barium studies in 11 (39%) of the 28 patients and reflux below the thoracic inlet or no reflux in the remaining 17 patients (61%) who comprised the control group. All 11 patients (100%) with massive reflux on barium studies had pathologic acid reflux on pH monitoring in the recumbent position compared with six (35%) of 17 patients in the control group (P=0.0009). The pH in the distal esophagus on pH monitoring was less than 4.0 for 13.1% of the recumbent period for patients with massive GER on barium studies compared with 6.2% of the recumbent period for the control group (P=0.0076). Conclusion: Although 24-h pH monitoring remains the gold standard for the detection of GER, our experience suggests that patients with massive reflux on barium studies are so likely to have pathologic acid reflux in the recumbent position that these individuals can be further evaluated and treated for their gastroesophageal reflux disease (GERD

  7. [A design and study of a novel electronic device for cuff-pressure monitoring].

    Science.gov (United States)

    Wang, Shupeng; Li, Wei; Li, Wen; Song, Dejing; Chen, Desheng; Duan, Jun; Li, Chen; Li, Gang

    2017-06-01

    To design a novel electronic device for measuring the pressure in the cuff of the artificial airway; and to study the advantage of this device on continuous and intermittent cuff pressure monitoring. (1) a portable electronic device for cuff pressure measurement was invented, which could turn pressure signal into electrical signal through a pressure transducer. Meantime, it was possible to avoid pressure leak from the joint and the inside of the apparatus by modified Luer taper and sophisticated design. If the cuff pressure was out of the normal range, the apparatus could release a sound and light alarm. (2) Six traditional mechanical manometers were used to determine the cuff pressure in 6 tracheal tubes. The cuff pressure was maintain at 30 cmH 2 O (1 cmH 2 O = 0.098 kPa) by the manometer first, and repeated every 30 seconds for 4 times. (3) Study of continuous cuff pressure monitoring: We used a random number generator to randomize 6 tracheal tubes, 6 mechanical manometers and 6 our products by number 1-6, which has the same number of a group. Every group was further randomized into two balanced groups, one group used the mechanical manometer first, and the other used our product first. The baseline pressure was 30 cmH 2 O, measurement was performed every 4 hours for 6 times. When traditional mechanical manometer was used for cuff pressure monitoring, cuff pressure was decreased by an average of 2.9 cmH 2 O for each measurement (F = 728.2, P = 0.000). In study of continually monitoring, at each monitoring point, the pressure measured by electronic manometer was higher than the mechanical manometer. All the pressures measured by mechanical manometer were dropped below 20 cmH 2 O at 8th hour, and there was no pressure decrease below 20 cmH 2 O measured by electronic manometer in 24 hours by contrast. In study of intermittent monitoring, the same result was found. The pressure was dropped significantly with time when measured by mechanical manometer (F = 61.795, P

  8. Retinal vascular imaging technology to monitor disease severity and complications in type 1 diabetes mellitus: A systematic review.

    Science.gov (United States)

    Kee, Ae Ra; Wong, Tien Yin; Li, Ling-Jun

    2017-02-01

    Type 1 diabetes mellitus (T1DM) is a major disease affecting a large number of young patients. In the recent years, retinal vascular imaging has provided an objective assessment of vascular health in patients with T1DM. Our study aimed to review the current literature on retinal vascular parameters in young patients with T1DM in order to understand the following: (i) How retinal vessels are affected in T1DM (ii) How such vascular changes can be predictive of future diabetic microvascular complications METHODS: We performed a systematic review and extracted relevant data from 17 articles. We found significant correlations between retinal vessel changes and diabetes-related risk factors (eg, hypertension, hyperlipidemia, and obesity), diabetes-related features (eg, diabetes duration and glycemic control), and diabetes-related microvascular complications (eg, diabetic retinopathy, nephropathy, and neuropathy). Our findings suggest that retinal microvasculature is associated with both disease severity and complications in young patients with T1DM. © 2016 John Wiley & Sons Ltd.

  9. Role of Diffusion Tensor Imaging in Prognostication and Treatment Monitoring in Niemann-Pick Disease Type C1

    Directory of Open Access Journals (Sweden)

    Meghann W. Lau

    2016-09-01

    Full Text Available Niemann-Pick Disease, type C1 (NPC1 is a rapidly progressive neurodegenerative disorder characterized by cholesterol sequestration within late endosomes and lysosomes, for which no reliable imaging marker exists for prognostication and management. Cerebellar volume deficits are found to correlate with disease severity and diffusion tensor imaging (DTI of the corpus callosum and brainstem, which has shown that microstructural disorganization is associated with NPC1 severity. This study investigates the utility of cerebellar DTI in clinical severity assessment. We hypothesize that cerebellar volume, fractional anisotropy (FA and mean diffusivity (MD negatively correlate with NIH NPC neurological severity score (NNSS and motor severity subscores. Magnetic resonance imaging (MRI was obtained for thirty-nine NPC1 subjects, ages 1–21.9 years (mean = 11.1, SD = 6.1. Using an atlas-based automated approach, the cerebellum of each patient was measured for FA, MD and volume. Additionally, each patient was given an NNSS. Decreased cerebellar FA and volume, and elevated MD correlate with higher NNSS. The cognition subscore and motor subscores for eye movement, ambulation, speech, swallowing, and fine motor skills were also statistically significant. Microstructural disorganization negatively correlated with motor severity in subjects. Additionally, Miglustat therapy correlated with lower severity scores across ranges of FA, MD and volume in all regions except the inferior peduncle, where a paradoxical effect was observed at high FA values. These findings suggest that DTI is a promising prognostication tool.

  10. Online Health Monitoring using Facebook Advertisement Audience Estimates in the United States: Evaluation Study.

    Science.gov (United States)

    Mejova, Yelena; Weber, Ingmar; Fernandez-Luque, Luis

    2018-03-28

    Facebook, the most popular social network with over one billion daily users, provides rich opportunities for its use in the health domain. Though much of Facebook's data are not available to outsiders, the company provides a tool for estimating the audience of Facebook advertisements, which includes aggregated information on the demographics and interests, such as weight loss or dieting, of Facebook users. This paper explores the potential uses of Facebook ad audience estimates for eHealth by studying the following: (1) for what type of health conditions prevalence estimates can be obtained via social media and (2) what type of marker interests are useful in obtaining such estimates, which can then be used for recruitment within online health interventions. The objective of this study was to understand the limitations and capabilities of using Facebook ad audience estimates for public health monitoring and as a recruitment tool for eHealth interventions. We use the Facebook Marketing application programming interface to correlate estimated sizes of audiences having health-related interests with public health data. Using several study cases, we identify both potential benefits and challenges in using this tool. We find several limitations in using Facebook ad audience estimates, for example, using placebo interest estimates to control for background level of user activity on the platform. Some Facebook interests such as plus-size clothing show encouraging levels of correlation (r=.74) across the 50 US states; however, we also sometimes find substantial correlations with the placebo interests such as r=.68 between interest in Technology and Obesity prevalence. Furthermore, we find demographic-specific peculiarities in the interests on health-related topics. Facebook's advertising platform provides aggregate data for more than 190 million US adults. We show how disease-specific marker interests can be used to model prevalence rates in a simple and intuitive manner

  11. Online Health Monitoring using Facebook Advertisement Audience Estimates in the United States: Evaluation Study

    Science.gov (United States)

    Weber, Ingmar; Fernandez-Luque, Luis

    2018-01-01

    Background Facebook, the most popular social network with over one billion daily users, provides rich opportunities for its use in the health domain. Though much of Facebook’s data are not available to outsiders, the company provides a tool for estimating the audience of Facebook advertisements, which includes aggregated information on the demographics and interests, such as weight loss or dieting, of Facebook users. This paper explores the potential uses of Facebook ad audience estimates for eHealth by studying the following: (1) for what type of health conditions prevalence estimates can be obtained via social media and (2) what type of marker interests are useful in obtaining such estimates, which can then be used for recruitment within online health interventions. Objective The objective of this study was to understand the limitations and capabilities of using Facebook ad audience estimates for public health monitoring and as a recruitment tool for eHealth interventions. Methods We use the Facebook Marketing application programming interface to correlate estimated sizes of audiences having health-related interests with public health data. Using several study cases, we identify both potential benefits and challenges in using this tool. Results We find several limitations in using Facebook ad audience estimates, for example, using placebo interest estimates to control for background level of user activity on the platform. Some Facebook interests such as plus-size clothing show encouraging levels of correlation (r=.74) across the 50 US states; however, we also sometimes find substantial correlations with the placebo interests such as r=.68 between interest in Technology and Obesity prevalence. Furthermore, we find demographic-specific peculiarities in the interests on health-related topics. Conclusions Facebook’s advertising platform provides aggregate data for more than 190 million US adults. We show how disease-specific marker interests can be used to model

  12. Design study of a bar-type EMR device

    KAUST Repository

    Sun, Jian; Gooneratne, Chinthaka Pasan; Kosel, Jü rgen

    2012-01-01

    It is well known that extraordinary magnetoresistance (EMR) depends on the geometric parameters of the EMR device and the locations of the electrodes. In this paper, the performance of a bar-type EMR device is simulated with respect to the device geometry and electrode locations. The performance is evaluated with regards to the output sensitivity of the device, rather than the often analyzed EMR ratio, since it is more relevant than the EMR ratio for potential applications ranging from read heads to smart biomedical sensors. The results obtained with the finite element method show the dependence of the output sensitivity on the device geometry the placements of the electric contacts as well as the strength of the applied magnetic field in different configurations and allow finding the optimum parameters. Within the studied range of -1 to 1 T both IVVI and VIIV configurations show very similar behavior. For EMR sensors of high sensitivity, the results suggest that a simple two-contact device would provide the best performance replacing the conventional four-contact design. © 2012 IEEE.

  13. Low cycle fatigue studies on a type 304 stainless steel

    International Nuclear Information System (INIS)

    Bhanu Sankara Rao, K.; Valsan, M.; Sandhya, R.; Ray, S.K.; Rodriguez, P.

    The effects of temperature and strain rate on the low cycle fatigue behaviour were investigated for an AISI 304 stainless steel under total axial strain control mode at 823 and 923 K. The fatigue life was strongly dependent on cyclic deformation rate for this material at these temperatures, decreasing markedly with decreasing strain rate. The cyclic stress-strain response recorded in the form of hysterisis loops exhibited serrations at low strain rates at 823 and 923 K. Cyclic stress-strain response at 823 K has shown an increase in saturation stress and decrease in plastic strain range whereas there is an increase in plastic strain range without marked variation in saturation stress level at 923 K with decreasing strain rate. It has been observed that there are three simultaneous effects namely environment, creep and cyclic strain ageing which contribute to the observed degradation in fatigue life at low strain rates. At 823 K, where the creep damage as well as environmental damage is relatively small, the fatigue life is considered mainly to be affected by dynamic strain ageing effect which depends on strain rate. At 923 K, on the other hand, the strain rate dependence of fatigue life is considered to be determined by the combination of creep and environmental effects. Deformation and fracture studies have also confirmed that the wedge type crack propagation is accelerated by oxidation effect. (author)

  14. Design study of a bar-type EMR device

    KAUST Repository

    Sun, Jian

    2012-05-01

    It is well known that extraordinary magnetoresistance (EMR) depends on the geometric parameters of the EMR device and the locations of the electrodes. In this paper, the performance of a bar-type EMR device is simulated with respect to the device geometry and electrode locations. The performance is evaluated with regards to the output sensitivity of the device, rather than the often analyzed EMR ratio, since it is more relevant than the EMR ratio for potential applications ranging from read heads to smart biomedical sensors. The results obtained with the finite element method show the dependence of the output sensitivity on the device geometry the placements of the electric contacts as well as the strength of the applied magnetic field in different configurations and allow finding the optimum parameters. Within the studied range of -1 to 1 T both IVVI and VIIV configurations show very similar behavior. For EMR sensors of high sensitivity, the results suggest that a simple two-contact device would provide the best performance replacing the conventional four-contact design. © 2012 IEEE.

  15. Study of the core compaction effects and its monitoring in sodium cooled fast reactors

    International Nuclear Information System (INIS)

    Zylbersztejn, F.

    2012-01-01

    Conclusions: • On calculation of reactivity impacts of core compaction/flowering: → Upper bound of the reactivity coefficients for each type of deformation; → Uniform compaction model: significant reactivity impact; Circular symmetric model: small reactivity impact. • On the visibility of these phenomena by the neutron detectors: → The direct monitoring of the core compaction by neutron detector in the BCC is not possible. (the identification that the reactivity perturbations observed are due to variation of the core geometry). Perspectives of solutions: → Improved core design: reducing the effects. → Physical improvements: Steel resistance to deformations (irradiation, flexion); Direct devices: core constraint (prevents deformations). → Additional calculations: Considering more localized deformations; Advanced monitoring with neutron noise (in progress)

  16. A theoretical case study of type I and type II beta-turns.

    Science.gov (United States)

    Czinki, Eszter; Császár, Attila G; Perczel, András

    2003-03-03

    NMR chemical shielding anisotropy tensors have been computed by employing a medium size basis set and the GIAO-DFT(B3LYP) formalism of electronic structure theory for all of the atoms of type I and type II beta-turn models. The models contain all possible combinations of the amino acid residues Gly, Ala, Val, and Ser, with all possible side-chain orientations where applicable in a dipeptide. The several hundred structures investigated contain either constrained or optimized phi, psi, and chi dihedral angles. A statistical analysis of the resulting large database was performed and multidimensional (2D and 3D) chemical-shift/chemical-shift plots were generated. The (1)H(alpha-13)C(alpha), (13)C(alpha-1)H(alpha-13)C(beta), and (13)C(alpha-1)H(alpha-13)C' 2D and 3D plots have the notable feature that the conformers clearly cluster in distinct regions. This allows straightforward identification of the backbone and side-chain conformations of the residues forming beta-turns. Chemical shift calculations on larger For-(L-Ala)(n)-NH(2) (n=4, 6, 8) models, containing a single type I or type II beta-turn, prove that the simple models employed are adequate. A limited number of chemical shift calculations performed at the highly correlated CCSD(T) level prove the adequacy of the computational method chosen. For all nuclei, statistically averaged theoretical and experimental shifts taken from the BioMagnetic Resonance Bank (BMRB) exhibit good correlation. These results confirm and extend our previous findings that chemical shift information from selected multiple-pulse NMR experiments could be employed directly to extract folding information for polypeptides and proteins.

  17. Studies on liposomes with Chlorophyll for monitoring the electromagnetic influence at molecular level

    International Nuclear Information System (INIS)

    Tugulea, Laura; Miclaus, Simona; Iacovache, Ioan

    2001-01-01

    The liposomes with Chlorophyll are excellent model membranes and could be successfully used to study the electromagnetic influence at molecular level. The strong visible absorption and fluorescence of Chlorophyll allow its use as sensor for the interactions at molecular level and as a fluorescence marker; it reflects certain aspects of the supramolecular structure of the lipid phase: fluidity, lipid and liposomes aggregation. The objective of our work was to evidence athermal effect of low level, pulsed microwave (MW) fields on liposomes and to evidence the possible mechanism of interaction at molecular level. Unilamellar liposomes were obtained from multilamellar vesicles by the hand-shaken method and sonication for 30 minutes. The multilamellar vesicles were prepared using Chla /lipid films with specific molar ratio (lipid/Chla 1/10 and 1/100) and different lipids (Dipalmitoyl phosphatidylcholine, Dimirystoyl Phosphatidylcholine and Dioleoyl Phosphatidylcholine-Sigma). The films were dispersed in buffer solutions of different pH (6.2 - 7.6). The Chlorophyll was freshly extracted from spinach leaves and separated by the chromatographic method. Portions of liposome suspension (0.6 ml) were inserted into Teflon cuvettes. The samples were irradiated in series, for periods of 5-30 minutes. The exposure system was: MW generator + adapted load (shortened rectangular waveguide) + Teflon cuvette filled with sample liquid. The effect of MW irradiation is not observable on multilamellar vesicles, but only on small unilamellar vesicles. The MW effect is athermal, verified by conventional heating in the same range of temperatures and results in enlarging the size of vesicles. The enlarging effect of MW is opposed to the effect of ultrasounds exposure. It is not clear if effects due to MW are proportional with exposure duration; it seems that this mostly depends on the type of lipid in vesicles. The UV and VIS spectra were recorded to observe the oxidation state of the

  18. Rare sugar D-allulose: Potential role and therapeutic monitoring in maintaining obesity and type 2 diabetes mellitus.

    Science.gov (United States)

    Hossain, Akram; Yamaguchi, Fuminori; Matsuo, Tatsuhiro; Tsukamoto, Ikuko; Toyoda, Yukiyasu; Ogawa, Masahiro; Nagata, Yasuo; Tokuda, Masaaki

    2015-11-01

    Obesity and type 2 diabetes mellitus (T2DM) are the leading worldwide risk factors for mortality. The inextricably interlinked pathological progression from excessive weight gain, obesity, and hyperglycemia to T2DM, usually commencing from obesity, typically originates from overconsumption of sugar and high-fat diets. Although most patients require medications, T2DM is manageable or even preventable with consumption of low-calorie diet and maintaining body weight. Medicines like insulin, metformin, and thiazolidinediones that improve glycemic control; however, these are associated with weight gain, high blood pressure, and dyslipidemia. These situations warrant the attentive consideration of the role of balanced foods. Recently, we have discovered advantages of a rare sugar, D-allulose, a zero-calorie functional sweetener having strong anti-hyperlipidemic and anti-hyperglycemic effects. Study revealed that after oral administration in rats D-allulose readily entered the blood stream and was eliminated into urine within 24h. Cell culture study showed that D-allulose enters into and leaves the intestinal enterocytes via glucose transporters GLUT5 and GLUT2, respectively. In addition to D-allulose's short-term effects, the characterization of long-term effects has been focused on preventing commencement and progression of T2DM in diabetic rats. Human trials showed that D-allulose attenuates postprandial glucose levels in healthy subjects and in borderline diabetic subjects. The anti-hyperlipidemic effect of D-allulose, combined with its anti-inflammatory actions on adipocytes, is beneficial for the prevention of both obesity and atherosclerosis and is accompanied by improvements in insulin resistance and impaired glucose tolerance. Therefore, this review presents brief discussions focusing on physiological functions and potential benefits of D-allulose on obesity and T2DM. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Photo-assisted Fenton type processes for the degradation of phenol: A kinetic study

    International Nuclear Information System (INIS)

    Kusic, Hrvoje; Koprivanac, Natalija; Bozic, Ana Loncaric; Selanec, Iva

    2006-01-01

    In this study the application of advanced oxidation processes (AOPs), dark Fenton and photo-assisted Fenton type processes; Fe 2+ /H 2 O 2 , Fe 3+ /H 2 O 2 , Fe 0 /H 2 O 2 , UV/Fe 2+ /H 2 O 2 , UV/Fe 3+ /H 2 O 2 and UV/Fe 0 /H 2 O 2 , for degradation of phenol as a model organic pollutant in the wastewater was investigated. A detail kinetic modeling which describes the degradation of phenol was performed. Mathematical models which predict phenol decomposition and formation of primary oxidation by-products: catechol, hydroquinone and benzoquinone, by applied processes were developed. The study also consist the modeling of mineralization kinetic of the phenol solution by applied AOPs. This part, besides well known reactions of Fenton and photo-Fenton chemistry, involves additional reactions which describe removal of iron from catalytic cycle through formation of ferric complexes and its regeneration induced by UV radiation. Phenol decomposition kinetic was monitored by HPLC analysis and total organic carbon content measurements (TOC). Complete phenol removal was obtained by all applied processes. Residual TOC by applied Fenton type processes ranged between 60.2 and 44.7%, while the efficiency of those processes was significantly enhanced in the presence of UV light, where residual TOC ranged between 15.2 and 2.4%

  20. The influence of emotion on keyboard typing: an experimental study using visual stimuli.

    Science.gov (United States)

    Lee, Po-Ming; Tsui, Wei-Hsuan; Hsiao, Tzu-Chien

    2014-06-20

    Emotion recognition technology plays the essential role of enhancement in Human-Computer Interaction (HCI). In recent years, a novel approach for emotion recognition has been reported, which is by keystroke dynamics. This approach can be considered to be rather desirable in HCI because the data used is rather non-intrusive and easy to obtain. However, there were only limited investigations about the phenomenon itself in previous studies. This study aims to examine the source of variance in keystroke typing patterns caused by emotions. A controlled experiment to collect subjects' keystroke data in different emotional states induced by International Affective Picture System (IAPS) was conducted. Two-way Valence (3) × Arousal (3) ANOVAs were used to examine the collected dataset. The results of the experiment indicate that the effect of emotion is significant (pemotional effect is small, compare to the individual variability. Our findings support the conclusion that the keystroke duration, keystroke latency, and also the accuracy rate of typing, are influenced by emotional states. Notably, the finding about the size of effect suggests that the accuracy rate of the emotion recognition could be further improved if personalized models are utilized. On the other hand, the finding also provides an explanation of why real-world applications which authenticate the identity of users by monitoring keystrokes may not be interfered by the emotional states of users. The experiment was conducted using standard instruments and hence is expected to be highly reproducible.

  1. Behavioral Analysis of Chinese Adult Patients with Type 1 Diabetes on Self-monitoring of Blood Glucose

    Directory of Open Access Journals (Sweden)

    Zhao-Yi Qin

    2017-01-01

    Conclusions: Adult patients with type 1 diabetes in our clinic had substantial SMBG information deficits, motivation obstacles, and skill limitations. This information provided potential-focused education targets for diabetes health-care providers.

  2. spa Typing and Multilocus Sequence Typing Show Comparable Performance in a Macroepidemiologic Study of Staphylococcus aureus in the United States.

    Science.gov (United States)

    O'Hara, F Patrick; Suaya, Jose A; Ray, G Thomas; Baxter, Roger; Brown, Megan L; Mera, Robertino M; Close, Nicole M; Thomas, Elizabeth; Amrine-Madsen, Heather

    2016-01-01

    A number of molecular typing methods have been developed for characterization of Staphylococcus aureus isolates. The utility of these systems depends on the nature of the investigation for which they are used. We compared two commonly used methods of molecular typing, multilocus sequence typing (MLST) (and its clustering algorithm, Based Upon Related Sequence Type [BURST]) with the staphylococcal protein A (spa) typing (and its clustering algorithm, Based Upon Repeat Pattern [BURP]), to assess the utility of these methods for macroepidemiology and evolutionary studies of S. aureus in the United States. We typed a total of 366 clinical isolates of S. aureus by these methods and evaluated indices of diversity and concordance values. Our results show that, when combined with the BURP clustering algorithm to delineate clonal lineages, spa typing produces results that are highly comparable with those produced by MLST/BURST. Therefore, spa typing is appropriate for use in macroepidemiology and evolutionary studies and, given its lower implementation cost, this method appears to be more efficient. The findings are robust and are consistent across different settings, patient ages, and specimen sources. Our results also support a model in which the methicillin-resistant S. aureus (MRSA) population in the United States comprises two major lineages (USA300 and USA100), which each consist of closely related variants.

  3. Medication adherence in type 2 diabetes patients: study of patients ...

    African Journals Online (AJOL)

    diabetes mellitus over the years, diabetes places an immense burden on the individuals living ... Key words: Diabetes type 2, adherence, glycemic level, health education and counselling. ... modifying dietary choices, implementing exercise re-.

  4. Periodontitis and Incident Type 2 Diabetes: a prospective cohort study

    OpenAIRE

    Winning, Lewis; Patterson, Christopher C; Neville, Charlotte E; Kee, Frank; Linden, Gerard J

    2016-01-01

    OBJECTIVES: To investigate periodontitis as a risk factor for incident type 2 diabetes mellitus (T2DM) in a group of men aged 58-72 years.METHODS: 1331 dentate, diabetes-free males in Northern Ireland underwent a detailed periodontal examination during 2001-2003. Follow-up was by bi-annual questionnaire and for those reporting diabetes their general medical practitioner was contacted to validate diabetes type, treatment and diagnosis date. Cox's proportional hazard models were used to estimat...

  5. Development of a program in LABVIEW platform to controlling and monitoring a Sievert-type system for comminution of metallic uranium and its alloys

    International Nuclear Information System (INIS)

    Dutra, Aimore R.R.; Ferraz, Wilmar B.; Ferreira, Ricardo A.N.

    2011-01-01

    A comminution process by hydriding-dehydriding method was developed at CDTN-Centro de Desenvolvimento da Tecnologia Nuclear with the purpose of obtaining plate type nuclear fuel. This fuel requires the use of metallic uranium and its alloys in form of powders. This comminution process was performed based on a Sievert system. Initially this system was controlled and monitored by a computer program developed in Turbo Pascal language. In order to improve the control of the comminution process, a new program was developed in LabVIEW platform. This paper presents a description of this new program and the main aspects of the operation of the system. The more accurate monitoring and controlling of the various stages of the comminution process as well as greater flexibility in the choice of input data, real-time graphics, generation of reports and a reduction of time passivation were achieved. (author)

  6. Development of a program in LABVIEW platform to controlling and monitoring Sievert-type system for comminution of metallic uranium and its alloys

    International Nuclear Information System (INIS)

    Dutra, Aimore R.R.; Ferraz, Wilmar B.; Ferreira, Ricardo A.N.

    2011-01-01

    A comminution process by hydriding-de hydriding method was developed at CDTN-Centro de Desenvolvimento da Tecnologia Nuclear with the purpose of obtaining plate type nuclear fuel. This fuel requires the use of metallic uranium and its alloys in form of powders. This comminution process was performed based on a Sievert system. Initially this system was controlled and monitored by a computer program developed in Turbo Pascal language. In order to improve the control of the comminution process, a new program was developed in LabVIEW platform. This paper presents a description of this new program and the main aspects of the operation of the system. The more accurate monitoring and controlling of the various stages of the comminution process as well as greater flexibility in the choice of input data, real-time graphics, generation of reports and a reduction of time passivation were achieved. (author)

  7. Development of a program in LABVIEW platform to controlling and monitoring a Sievert-type system for comminution of metallic uranium and its alloys

    Energy Technology Data Exchange (ETDEWEB)

    Dutra, Aimore R.R.; Ferraz, Wilmar B.; Ferreira, Ricardo A.N., E-mail: ferrazw@cdtn.b, E-mail: ranf@cdtn.b [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2011-07-01

    A comminution process by hydriding-dehydriding method was developed at CDTN-Centro de Desenvolvimento da Tecnologia Nuclear with the purpose of obtaining plate type nuclear fuel. This fuel requires the use of metallic uranium and its alloys in form of powders. This comminution process was performed based on a Sievert system. Initially this system was controlled and monitored by a computer program developed in Turbo Pascal language. In order to improve the control of the comminution process, a new program was developed in LabVIEW platform. This paper presents a description of this new program and the main aspects of the operation of the system. The more accurate monitoring and controlling of the various stages of the comminution process as well as greater flexibility in the choice of input data, real-time graphics, generation of reports and a reduction of time passivation were achieved. (author)

  8. Development of a program in LABVIEW platform to controlling and monitoring Sievert-type system for comminution of metallic uranium and its alloys

    Energy Technology Data Exchange (ETDEWEB)

    Dutra, Aimore R.R.; Ferraz, Wilmar B.; Ferreira, Ricardo A.N., E-mail: ferrazw@cdtn.b, E-mail: ranf@cdtn.b [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2011-07-01

    A comminution process by hydriding-de hydriding method was developed at CDTN-Centro de Desenvolvimento da Tecnologia Nuclear with the purpose of obtaining plate type nuclear fuel. This fuel requires the use of metallic uranium and its alloys in form of powders. This comminution process was performed based on a Sievert system. Initially this system was controlled and monitored by a computer program developed in Turbo Pascal language. In order to improve the control of the comminution process, a new program was developed in LabVIEW platform. This paper presents a description of this new program and the main aspects of the operation of the system. The more accurate monitoring and controlling of the various stages of the comminution process as well as greater flexibility in the choice of input data, real-time graphics, generation of reports and a reduction of time passivation were achieved. (author)

  9. Low-temperature radiation damage in silicon - 1: Annealing studies on N-type material

    International Nuclear Information System (INIS)

    Awadelkarim, O.O.

    1986-07-01

    The presence of electrically active defects in electron-irradiated P-doped n-type silicon was monitored using capacitance and loss factor measurements. Irradiations were performed at temperatures c - 0.14) eV and (E c - 0.24) eV in the gap are ascribed to the carbon interstitial and the divacancy, respectively. (author)

  10. Protective effects of parental monitoring of children's media use: a prospective study.

    Science.gov (United States)

    Gentile, Douglas A; Reimer, Rachel A; Nathanson, Amy I; Walsh, David A; Eisenmann, Joey C

    2014-05-01

    Children spend more time with electronic media than they do in any other activity, aside from sleep. Many of the negative effects that stem from media exposure may be reduced by parental monitoring of children's media use; however, there lacks a clear understanding of the mechanisms and extent of these protective effects. To determine the prospective effects of parental monitoring of children's media on physical, social, and academic outcomes. Prospective cohort design. Data were collected by in-home and in-school surveys in 2 communities in Iowa and Minnesota, where 1323 third- (n = 430), fourth- (n = 446), and fifth- (n = 423) grade students participated. A primary caregiver and teachers also provided data about the student. Participants in the current study were recruited to participate in a social ecological model-based obesity prevention program. Body mass index, average weekly sleep, school performance, prosocial behavior, and aggressive behavior. RESULTS Structural equation modeling revealed that parental monitoring of children's media influences children's sleep, school performance, and prosocial and aggressive behaviors and that these effects are mediated through total screen time and exposure to media violence. Parental monitoring of media has protective effects on a wide variety of academic, social, and physical child outcomes. Pediatricians and physicians are uniquely positioned to provide scientifically based recommendations to families; encouraging parents to monitor children's media carefully can have a wide range of health benefits for children.

  11. A prospective study of monitoring practices for metabolic disease in antipsychotic-treated community psychiatric patients

    Directory of Open Access Journals (Sweden)

    Watkinson Helen MO

    2007-06-01

    Full Text Available Abstract Background Patients with severe mental illness are at increased risk for metabolic and cardiovascular disease. A number of recent guidelines and consensus statements recommend stringent monitoring of metabolic function in individuals receiving antipsychotic drugs. Methods We conducted a prospective cohort study of 106 community-treated psychiatric patients from across the diagnostic spectrum from the Northeast of England to investigate changes in metabolic status and monitoring practices for metabolic and cardiovascular disease. We undertook detailed anthropometric and metabolic assessment at baseline and follow-up, and examined clinical notes and hospital laboratory records to ascertain monitoring practices. Results A high prevalence of undiagnosed and untreated metabolic disease was present at baseline assessment. Mean follow-up time was 599.3 (SD ± 235.4 days. Body mass index (p 50% of subjects had neither blood glucose nor lipids monitored during the follow-up period. Conclusion This cohort has a high prevalence of metabolic disease and heightened cardiovascular risk. Despite the publication of a number of recommendations regarding physical health screening in this population, monitoring rates are poor, and physical health worsened during the follow-up period.

  12. Genotype–phenotype study of familial haemophagocytic lymphohistiocytosis type 3

    Science.gov (United States)

    Sieni, Elena; Cetica, Valentina; Santoro, Alessandra; Beutel, Karin; Mastrodicasa, Elena; Meeths, Marie; Ciambotti, Benedetta; Brugnolo, Francesca; zur Stadt, Udo; Pende, Daniela; Moretta, Lorenzo; Griffiths, Gillian M; Henter, Jan-Inge; Janka, Gritta; Aricò, Maurizio

    2014-01-01

    Background Mutations of UNC13D are causative for familial haemophagocytic lymphohistiocytosis type 3 (FHL3; OMIM 608898). Objective To carry out a genotype–phenotype study of patients with FHL3. Methods A consortium of three countries pooled data on presenting features and mutations from individual patients with biallelic UNC13D mutations in a common database. Results 84 patients with FHL3 (median age 4.1 months) were reported from Florence, Italy (n=54), Hamburg, Germany (n=18), Stockholm, Sweden (n=12). Their ethnic origin was Caucasian (n=57), Turkish (n=10), Asian (n=7), Hispanic (n=4), African (n=3) (not reported (n=3)). Thrombocytopenia was present in 94%, splenomegaly in 96%, fever in 89%. The central nervous system (CNS) was involved in 49/81 (60%) patients versus 36% in patients with FHL2 (p=0.001). A combination of fever, splenomegaly, thrombocytopenia and hyperferritinaemia was present in 71%. CD107a expression, NK activity and Munc 13-4 protein expression were absent or reduced in all but one of the evaluated patients. 54 different mutations were observed, including 15 new ones: 19 missense, 14 deletions or insertions, 12 nonsense, nine splice errors. None was specific for ethnic groups. Patients with two disruptive mutations were younger than patients with two missense mutations (p<0.001), but older than comparable patients with FHL2 (p=0.001). Conclusion UNC13D mutations are scattered over the gene. Ethnic-specific mutations were not identified. CNS involvement is more common than in FHL2; in patients with FHL3 and disruptive mutations, age at diagnosis is significantly higher than in FHL2. The combination of fever, splenomegaly, thrombocytopenia and hyperferritinaemia appears to be the most easily and frequently recognised clinical pattern and their association with defective granule release assay may herald FHL3. PMID:21248318

  13. Neuroimaging study of Fukuyama type congenital muscular dystrophy

    International Nuclear Information System (INIS)

    Murasugi, Hiroko

    1992-01-01

    Fukuyama type congenital muscular dystrophy (FCMD) has been attracting attention in recent years because of its brain malformation and progressive muscular dystrophy. The intravitam recognition of brain malformation has been remarkably enhanced by the advent of noninvasive neuroimaging techniques such as CT and MRI. In this study, 87 cranial CT scans and 22 MRIs of the brain, carried out on 60 patients with FCMD, were systematically surveyed, and the correlation between neuroradiological findings and clinical disabilities, and, in two autopsy cases, neuropathological findings was evaluated. Four cases of lissencephalic, 29 of pachygyric, and one of polymicrogyric (suspected) brain surface, and 2 normal brain surfaces were recognized. The patients with lissencephalic brain surface were compared using Dobyns' criteria. Grading of pachygyria was judged as bilateral II in 52% of cases and bilateral I in 48%. The surface of the occipital lobe could not be confirmed with either CT or MRI. Polymicrogyria was suspected using MRI but could not confirmed with CT. Five caces of lissencephaly had never learned any meaningful words and all but one were bedridden because of poor head control. The abilities of patients were better when the grading of pachygyria was milder. Mental disability and peak motor function correlate more closely with the degree and extent of brain malformation than with muscle degeneration. The decrease in radiodensity in the white matter was remarkable in 12 out of 19 cases (63%), and was usually bilaterally symmetrical. An increase in radiodensity in the white matter with age was observed in 3 patients. The rate of myelination was slower than normal in 3 out of the 6 cases. (author)

  14. Neuroimaging study of Fukuyama type congenital muscular dystrophy

    Energy Technology Data Exchange (ETDEWEB)

    Murasugi, Hiroko (Tokyo Women' s Medical Coll. (Japan))

    1992-11-01

    Fukuyama type congenital muscular dystrophy (FCMD) has been attracting attention in recent years because of its brain malformation and progressive muscular dystrophy. The intravitam recognition of brain malformation has been remarkably enhanced by the advent of noninvasive neuroimaging techniques such as CT and MRI. In this study, 87 cranial CT scans and 22 MRIs of the brain, carried out on 60 patients with FCMD, were systematically surveyed, and the correlation between neuroradiological findings and clinical disabilities, and, in two autopsy cases, neuropathological findings was evaluated. Four cases of lissencephalic, 29 of pachygyric, and one of polymicrogyric (suspected) brain surface, and 2 normal brain surfaces were recognized. The patients with lissencephalic brain surface were compared using Dobyns' criteria. Grading of pachygyria was judged as bilateral II in 52% of cases and bilateral I in 48%. The surface of the occipital lobe could not be confirmed with either CT or MRI. Polymicrogyria was suspected using MRI but could not confirmed with CT. Five caces of lissencephaly had never learned any meaningful words and all but one were bedridden because of poor head control. The abilities of patients were better when the grading of pachygyria was milder. Mental disability and peak motor function correlate more closely with the degree and extent of brain malformation than with muscle degeneration. The decrease in radiodensity in the white matter was remarkable in 12 out of 19 cases (63%), and was usually bilaterally symmetrical. An increase in radiodensity in the white matter with age was observed in 3 patients. The rate of myelination was slower than normal in 3 out of the 6 cases. (author).

  15. Advances in study of reporter gene imaging for monitoring gene therapy

    International Nuclear Information System (INIS)

    Mu Chuanjie; Zhou Jiwen

    2003-01-01

    To evaluate the efficiency of gene therapy, it is requisite to monitor localization and expression of the therapeutic gene in vivo. Monitoring expression of reporter gene using radionuclide reporter gene technique is the best method. Adenoviral vectors expressing reporter gene are constructed using gene fusion, bicistronic, double promoter or bidirectional transcriptional recombination techniques, and transferred into target cells and tissues, then injected radiolabeled reporter probes which couple to the reporter genes. The reporter genes can be imaged invasively, repeatedly, quantitatively with γ-camera, PET and SPECT. Recently, several reporter gene and reporter probe systems have been used in studies of gene therapy. The part of them has been used for clinic trials

  16. How Many Days Are Enough? A Study of 365 Days of Pedometer Monitoring

    Science.gov (United States)

    Kang, Minsoo; Bassett, David R.; Barreira, Tiago V.; Tudor-Locke, Catrine; Ainsworth, Barbara; Reis, Jared P.; Strath, Scott; Swartz, Ann

    2009-01-01

    This study was designed to determine the number of days of pedometer monitoring necessary to achieve reliable and valid estimates of a 1-year average of step counts in adults based on either consecutive days (CD) or random days (RD) of data collection. Twenty-three participants (16 women; M age = 38 years, SD = 9.9) wore a Yamax SW 200 pedometer…

  17. The diesel exhaust in miners study: II. Exposure monitoring surveys and development of exposure groups.

    NARCIS (Netherlands)

    Coble, J.B.; Stewart, P.A.; Vermeulen, R.; Yereb, D.; Stanevich, R.; Blair, A.; Silverman, D.T.; Attfield, M.

    2010-01-01

    Air monitoring surveys were conducted between 1998 and 2001 at seven non-metal mining facilities to assess exposure to respirable elemental carbon (REC), a component of diesel exhaust (DE), for an epidemiologic study of miners exposed to DE. Personal exposure measurements were taken on workers in a

  18. An application study for the class 1E digital control and monitoring system

    International Nuclear Information System (INIS)

    Hiroyuki Fukumitsu

    1998-01-01

    This paper presents an application study for the Class 1E digital control and monitoring system to the next Japanese plants, especially about MMIS. The system architecture of hardware and software is also introduced, which will explain the strategic plan for the necessary software verification and validation according to the latest requirement from Japanese regulatory guide. (author)

  19. Cutaneous respirometry as novel technique to monitor mitochondrial function: A feasibility study in healthy volunteers

    NARCIS (Netherlands)

    F.A. Harms (Floor A.); R.J. Stolker (Robert); E.G. Mik (Egbert)

    2016-01-01

    textabstractBackground: The protoporphyrin IX-triplet state lifetime technique (PpIX-TSLT) is proposed as a potential clinical non-invasive tool to monitor mitochondrial function. This technique has been evaluated in several animal studies. Mitochondrial respirometry allows measurement in vivo of

  20. Auditing for Score Inflation Using Self-Monitoring Assessments: Findings from Three Pilot Studies

    Science.gov (United States)

    Koretz, Daniel; Jennings, Jennifer L.; Ng, Hui Leng; Yu, Carol; Braslow, David; Langi, Meredith

    2016-01-01

    Test-based accountability often produces score inflation. Most studies have evaluated inflation by comparing trends on a high-stakes test and a lower stakes audit test. However, Koretz and Beguin (2010) noted weaknesses of audit tests and suggested self-monitoring assessments (SMAs), which incorporate audit items into high-stakes tests. This…

  1. Monitoring of Dips in the MV Network for Regulation- A Case Study

    NARCIS (Netherlands)

    Weldemariam, L.E.; Cuk, V.; Cobben, J.F.G.; Kling, W.L.

    2014-01-01

    Abstract— Voltage dips constitute to a noticeable part of power quality (PQ) problems but causing major financial losses to industrial and commercial customers. This work involves comparative studies to choose the most appropriate location of monitoring dips for regulation. In this paper, a Dutch MV

  2. Required sample size for monitoring stand dynamics in strict forest reserves: a case study

    Science.gov (United States)

    Diego Van Den Meersschaut; Bart De Cuyper; Kris Vandekerkhove; Noel Lust

    2000-01-01

    Stand dynamics in European strict forest reserves are commonly monitored using inventory densities of 5 to 15 percent of the total surface. The assumption that these densities guarantee a representative image of certain parameters is critically analyzed in a case study for the parameters basal area and stem number. The required sample sizes for different accuracy and...

  3. Acquiring L2 Sentence Comprehension: A Longitudinal Study of Word Monitoring in Noise

    Science.gov (United States)

    Oliver, Georgina; Gullberg, Marianne; Hellwig, Frauke; Mitterer, Holger; Indefrey, Peter

    2012-01-01

    This study investigated the development of second language online auditory processing with ab initio German learners of Dutch. We assessed the influence of different levels of background noise and different levels of semantic and syntactic target word predictability on word-monitoring latencies. There was evidence of syntactic, but not…

  4. Water Quality Monitoring: An Environmental Studies Unit for Biology 20/30. Teacher's Guide.

    Science.gov (United States)

    Alberta Environment, Edmonton. Environmental Education Resources Branch.

    The objective of this environmental studies unit is to establish a water quality monitoring project for high school students in Alberta while simultaneously providing a unit which meets the objectives of the Biology 20 program (and which may also be used in Biology 10 and 30). Through this project, students assist in the collection,…

  5. Water Quality Monitoring: An Environmental Studies Unit for Biology 20/30. Student Manual.

    Science.gov (United States)

    Alberta Environment, Edmonton. Environmental Education Resources Branch.

    The objective of this environmental studies unit is to establish a water quality monitoring project for high school students in Alberta while simultaneously providing a unit which meets the objectives of the Biology 20 program (and which may also be used in Biology 10 and 30). Through this project, students assist in the collection,…

  6. Efficacy and safety of teneligliptin in addition to insulin therapy in type 2 diabetes mellitus patients on hemodialysis evaluated by continuous glucose monitoring.

    Science.gov (United States)

    Yajima, Takahiro; Yajima, Kumiko; Hayashi, Makoto; Takahashi, Hiroshi; Yasuda, Keigo

    2016-12-01

    Appropriate glycemic control without hypoglycemia is important in patients with type 2 diabetes on hemodialysis. Teneligliptin, a novel dipeptidyl peptidase-4 inhibitor, can be used without dose adjustment for these patients. Using continuous glucose monitoring (CGM), we evaluated the efficacy and safety of adding teneligliptin to insulin therapy. Twenty-one type 2 diabetes mellitus patients on hemodialysis treated with insulin were enrolled. After the adjustment of insulin dose, their blood glucose level was monitored by CGM. Insulin dose was reduced after teneligliptin administration. The median total daily insulin dose significantly reduced from 18 (9-24)U to 6 (0-14)U (p1). Maximum, mean, and standard deviation of blood glucose level on the hemodialysis and non-hemodialysis days did not change after teneligliptin administration. However, minimum blood glucose level was significantly elevated on the hemodialysis day after teneligliptin administration (from 3.9±1.0mmol/L to 4.4±0.9mmol/L, p=0.040). The incidence of asymptomatic hypoglycemia on the he