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Sample records for models develop fast

  1. Developing Fast and Reliable Flood Models

    DEFF Research Database (Denmark)

    Thrysøe, Cecilie; Toke, Jens; Borup, Morten

    2016-01-01

    State-of-the-art flood modelling in urban areas are based on distributed physically based models. However, their usage is impeded by high computational demands and numerical instabilities, which make calculations both difficult and time consuming. To address these challenges we develop and test...... is modelled by response surface surrogates, which are empirical data driven models. These are trained using the volume-discharge relations by piecewise linear functions. (ii) The surface flooding is modelled by lower-fidelity physically based surrogates, which are based on surface depressions and flow paths....... A surrogate model is set up for a case study area in Aarhus, Denmark, to replace a MIKE FLOOD model. The drainage surrogates are able to reproduce the MIKE URBAN results for a set of rain inputs. The coupled drainage-surface surrogate model lacks details in the surface description which reduces its overall...

  2. BISON and MARMOT Development for Modeling Fast Reactor Fuel Performance

    Energy Technology Data Exchange (ETDEWEB)

    Gamble, Kyle Allan Lawrence [Idaho National Lab. (INL), Idaho Falls, ID (United States); Williamson, Richard L. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Schwen, Daniel [Idaho National Lab. (INL), Idaho Falls, ID (United States); Zhang, Yongfeng [Idaho National Lab. (INL), Idaho Falls, ID (United States); Novascone, Stephen Rhead [Idaho National Lab. (INL), Idaho Falls, ID (United States); Medvedev, Pavel G. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-09-01

    BISON and MARMOT are two codes under development at the Idaho National Laboratory for engineering scale and lower length scale fuel performance modeling. It is desired to add capabilities for fast reactor applications to these codes. The fast reactor fuel types under consideration are metal (U-Pu-Zr) and oxide (MOX). The cladding types of interest include 316SS, D9, and HT9. The purpose of this report is to outline the proposed plans for code development and provide an overview of the models added to the BISON and MARMOT codes for fast reactor fuel behavior. A brief overview of preliminary discussions on the formation of a bilateral agreement between the Idaho National Laboratory and the National Nuclear Laboratory in the United Kingdom is presented.

  3. Jobs and Economic Development Impact (JEDI) User Reference Guide: Fast Pyrolysis Biorefinery Model

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Yimin [National Renewable Energy Lab. (NREL), Golden, CO (United States); Goldberg, Marshall [MRG and Associates, Nevada City, CA (United States)

    2015-02-01

    This guide -- the JEDI Fast Pyrolysis Biorefinery Model User Reference Guide -- was developed to assist users in operating and understanding the JEDI Fast Pyrolysis Biorefinery Model. The guide provides information on the model's underlying methodology, as well as the parameters and data sources used to develop the cost data utilized in the model. This guide also provides basic instruction on model add-in features and a discussion of how the results should be interpreted. Based on project-specific inputs from the user, the JEDI Fast Pyrolysis Biorefinery Model estimates local (e.g., county- or state-level) job creation, earnings, and output from total economic activity for a given fast pyrolysis biorefinery. These estimates include the direct, indirect and induced economic impacts to the local economy associated with the construction and operation phases of biorefinery projects.Local revenue and supply chain impacts as well as induced impacts are estimated using economic multipliers derived from the IMPLAN software program. By determining the local economic impacts and job creation for a proposed biorefinery, the JEDI Fast Pyrolysis Biorefinery Model can be used to field questions about the added value biorefineries might bring to a local community.

  4. Wind turbine control systems: Dynamic model development using system identification and the fast structural dynamics code

    Energy Technology Data Exchange (ETDEWEB)

    Stuart, J.G.; Wright, A.D.; Butterfield, C.P.

    1996-10-01

    Mitigating the effects of damaging wind turbine loads and responses extends the lifetime of the turbine and, consequently, reduces the associated Cost of Energy (COE). Active control of aerodynamic devices is one option for achieving wind turbine load mitigation. Generally speaking, control system design and analysis requires a reasonable dynamic model of {open_quotes}plant,{close_quotes} (i.e., the system being controlled). This paper extends the wind turbine aileron control research, previously conducted at the National Wind Technology Center (NWTC), by presenting a more detailed development of the wind turbine dynamic model. In prior research, active aileron control designs were implemented in an existing wind turbine structural dynamics code, FAST (Fatigue, Aerodynamics, Structures, and Turbulence). In this paper, the FAST code is used, in conjunction with system identification, to generate a wind turbine dynamic model for use in active aileron control system design. The FAST code is described and an overview of the system identification technique is presented. An aileron control case study is used to demonstrate this modeling technique. The results of the case study are then used to propose ideas for generalizing this technique for creating dynamic models for other wind turbine control applications.

  5. Development of models for fast fluid pathways through unsaturated heterogeneous porous media

    Energy Technology Data Exchange (ETDEWEB)

    Robey, T.H. [Spectra Research Inst., Albuquerque, NM (United States)

    1994-11-01

    The pre-waste-emplacement ground water travel time requirement is a regulatory criterion that specifies ground water travel time to the accessible environment shall be greater than 1,000 years. Satisfying the ground water travel time criterion for the potential repository at Yucca Mountain requires the study of fast travel path formation in the unsaturated zone and development of models that simulate the formation of fast paths. Conceptual models for unsaturated flow that have been used for total-systems performance assessment generally fall into the categories of composite-porosity or fracture models. The actual hydrologic conditions at Yucca Mountain are thought to lie somewhere between the extremes of these two types of models. The current study considers the effects of heterogeneities on composite-porosity models and seeks to develop numerical methods (and models) that can produce locally saturated zones where fracture flow can occur. The credibility of the model and numerical methods is investigated by using test data from the INTRAVAL project (Swedish Nuclear Inspectorate, 1992) to attempt to predict in-situ volumetric water content at specific locations in Yucca Mountain. Work based on the numerical methods presented in this study is eventually intended to allow the calculation of ground water travel times in heterogeneous media. 60 refs.

  6. Development and application of modeling tools for sodium fast reactor inspection

    Science.gov (United States)

    Le Bourdais, Florian; Marchand, Benoît; Baronian, Vahan

    2014-02-01

    To support the development of in-service inspection methods for the Advanced Sodium Test Reactor for Industrial Demonstration (ASTRID) project led by the French Atomic Energy Commission (CEA), several tools that allow situations specific to Sodium cooled Fast Reactors (SFR) to be modeled have been implemented in the CIVA software and exploited. This paper details specific applications and results obtained. For instance, a new specular reflection model allows the calculation of complex echoes from scattering structures inside the reactor vessel. EMAT transducer simulation models have been implemented to develop new transducers for sodium visualization and imaging. Guided wave analysis tools have been developed to permit defect detection in the vessel shell. Application examples and comparisons with experimental data are presented.

  7. Development and validation of a two-dimensional fast-response flood estimation model

    Energy Technology Data Exchange (ETDEWEB)

    Judi, David R [Los Alamos National Laboratory; Mcpherson, Timothy N [Los Alamos National Laboratory; Burian, Steven J [UNIV OF UTAK

    2009-01-01

    A finite difference formulation of the shallow water equations using an upwind differencing method was developed maintaining computational efficiency and accuracy such that it can be used as a fast-response flood estimation tool. The model was validated using both laboratory controlled experiments and an actual dam breach. Through the laboratory experiments, the model was shown to give good estimations of depth and velocity when compared to the measured data, as well as when compared to a more complex two-dimensional model. Additionally, the model was compared to high water mark data obtained from the failure of the Taum Sauk dam. The simulated inundation extent agreed well with the observed extent, with the most notable differences resulting from the inability to model sediment transport. The results of these validation studies complex two-dimensional model. Additionally, the model was compared to high water mark data obtained from the failure of the Taum Sauk dam. The simulated inundation extent agreed well with the observed extent, with the most notable differences resulting from the inability to model sediment transport. The results of these validation studies show that a relatively numerical scheme used to solve the complete shallow water equations can be used to accurately estimate flood inundation. Future work will focus on further reducing the computation time needed to provide flood inundation estimates for fast-response analyses. This will be accomplished through the efficient use of multi-core, multi-processor computers coupled with an efficient domain-tracking algorithm, as well as an understanding of the impacts of grid resolution on model results.

  8. A fast and systematic procedure to develop dynamic models of bioprocesses: application to microalgae cultures

    Directory of Open Access Journals (Sweden)

    J. Mailier

    2010-09-01

    Full Text Available The purpose of this paper is to report on the development of a procedure for inferring black-box, yet biologically interpretable, dynamic models of bioprocesses based on sets of measurements of a few external components (biomass, substrates, and products of interest. The procedure has three main steps: (a the determination of the number of macroscopic biological reactions linking the measured components; (b the estimation of a first reaction scheme, which has interesting mathematical properties, but might lack a biological interpretation; and (c the "projection" (or transformation of this reaction scheme onto a biologically-consistent scheme. The advantage of the method is that it allows the fast prototyping of models for the culture of microorganisms that are not well documented. The good performance of the third step of the method is demonstrated by application to an example of microalgal culture.

  9. Development of Spectral and Atomic Models for Diagnosing Energetic Particle Characteristics in Fast Ignition Experiments

    Energy Technology Data Exchange (ETDEWEB)

    MacFarlane, Joseph J [Prism Computational Sciences

    2009-08-07

    This Final Report summarizes work performed under DOE STTR Phase II Grant No. DE-FG02-05ER86258 during the project period from August 2006 to August 2009. The project, “Development of Spectral and Atomic Models for Diagnosing Energetic Particle Characteristics in Fast Ignition Experiments,” was led by Prism Computational Sciences (Madison, WI), and involved collaboration with subcontractors University of Nevada-Reno and Voss Scientific (Albuquerque, NM). In this project, we have: Developed and implemented a multi-dimensional, multi-frequency radiation transport model in the LSP hybrid fluid-PIC (particle-in-cell) code [1,2]. Updated the LSP code to support the use of accurate equation-of-state (EOS) tables generated by Prism’s PROPACEOS [3] code to compute more accurate temperatures in high energy density physics (HEDP) plasmas. Updated LSP to support the use of Prism’s multi-frequency opacity tables. Generated equation of state and opacity data for LSP simulations for several materials being used in plasma jet experimental studies. Developed and implemented parallel processing techniques for the radiation physics algorithms in LSP. Benchmarked the new radiation transport and radiation physics algorithms in LSP and compared simulation results with analytic solutions and results from numerical radiation-hydrodynamics calculations. Performed simulations using Prism radiation physics codes to address issues related to radiative cooling and ionization dynamics in plasma jet experiments. Performed simulations to study the effects of radiation transport and radiation losses due to electrode contaminants in plasma jet experiments. Updated the LSP code to generate output using NetCDF to provide a better, more flexible interface to SPECT3D [4] in order to post-process LSP output. Updated the SPECT3D code to better support the post-processing of large-scale 2-D and 3-D datasets generated by simulation codes such as LSP. Updated atomic physics modeling to provide for

  10. Development of a fast response dispersion model for virtual urban environments

    Science.gov (United States)

    Singh, Balwinder

    According to a UN report, more than 50% of the total world's population resides in urban areas and this fraction is increasing. Urbanization has a wide range of potential environmental impacts, including those related to the dispersion of potentially dangerous substances emitted from activities such as combustion, industrial processing or from deliberate harmful releases. This research is primarily focused on the investigation of various factors which contribute to the dispersion of certain classes of materials in a complex urban environment and improving both of the fundamental components of a fast response dispersion modeling system---wind modeling and dispersion modeling. Specifically, new empirical parameterizations have been suggested for an existing fast response wind model for street canyon flow fields. These new parameterizations are shown to produce more favorable results when compared with the experimental data. It is also demonstrated that the use of Graphics Processing Unit (GPU) technology can enhance the efficiency of an urban Lagrangian dispersion model and can achieve near real-time particle advection. The GPU also enables real-time visualizations which can be used for creating virtual urban environments to aid emergency responders. The dispersion model based on the GPU architecture relies on the so-called "simplified Langevin equations (SLEs)" for particle advection. The full or generalized form of the Langevin equations (GLEs) is known for its stiffness which tends to generate unstable modes in particle trajectory, where a particle may travel significant distances in a small time step. A fractional step methodology has been used to implement the GLEs into an existing Lagrangian random walk model to partially circumvent the stiffness associated with the GLEs. Dispersion estimates from the GLEs-based model have been compared with the SLEs-based model and available wind tunnel data. The GLEs-based model is more dispersive than the SLEs-based model in

  11. RCD+: Fast loop modeling server.

    Science.gov (United States)

    López-Blanco, José Ramón; Canosa-Valls, Alejandro Jesús; Li, Yaohang; Chacón, Pablo

    2016-07-08

    Modeling loops is a critical and challenging step in protein modeling and prediction. We have developed a quick online service (http://rcd.chaconlab.org) for ab initio loop modeling combining a coarse-grained conformational search with a full-atom refinement. Our original Random Coordinate Descent (RCD) loop closure algorithm has been greatly improved to enrich the sampling distribution towards near-native conformations. These improvements include a new workflow optimization, MPI-parallelization and fast backbone angle sampling based on neighbor-dependent Ramachandran probability distributions. The server starts by efficiently searching the vast conformational space from only the loop sequence information and the environment atomic coordinates. The generated closed loop models are subsequently ranked using a fast distance-orientation dependent energy filter. Top ranked loops are refined with the Rosetta energy function to obtain accurate all-atom predictions that can be interactively inspected in an user-friendly web interface. Using standard benchmarks, the average root mean squared deviation (RMSD) is 0.8 and 1.4 Å for 8 and 12 residues loops, respectively, in the challenging modeling scenario in where the side chains of the loop environment are fully remodeled. These results are not only very competitive compared to those obtained with public state of the art methods, but also they are obtained ∼10-fold faster. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  12. DEVELOPMENT OF A NOVEL EMPIRICAL MODEL TO ESTIMATE THE KRAFT PULP YIELD OF FAST-GROWING EUCALYPTUS

    Directory of Open Access Journals (Sweden)

    Jing Liu,

    2012-01-01

    Full Text Available In this study, several kraft pulps were produced by kraft pulping of fast-growing Eucalyptus with a wide range of cooking conditions. The dependences between pulp yields and some pulp properties, namely, kappa number, HexA contents, and cellulose viscosities, were well investigated. It was found that kraft pulp yields linearly decreased with the reduction of HexA-free kappa number in two different stages, respectively, in which a transition point of measured pulp yield of 48.7% was observed. A similar relationship between pulp yield and HexA was also found, in which the resulting transition point of HexA content was 67 μmol/g. Moreover, the logarithm of pulp viscosity was linearly proportional to the reduction of lignin-free pulp yields. Then, a novel empirical model was successfully developed based on these findings. The parameters in this empirical model were calculated by least-squares estimation using the experimental data from active alkali values of 13.2, 14.7 and 17.8. Another data set was used to verify the effectiveness of this model in predicting the pulp yields. Finally, a good agreement (a linear regression coefficient of 90.59% between experimental and fitting data was obtained, which indicated that the kraft pulp yield of fast-growing Eucalyptus could be accurately predicted by this novel empirical model.

  13. A Plan for the Development of the Spatial Kinetics and the Detailed Reactivity Model for a Fast Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Y. M.; Jeong, H. Y.; Lee, Y. B.; Sim, Y. S

    2005-11-15

    The reactivity feedback effect of metallic fuel is determined by the fuel burnup characteristics, the configuration of core and fuel assembly, and the complicated interaction between the fuel assembly and core internal structures. Currently, a quite simple evaluation model is frequently applied for the calculation of reactivity feedback. The simple model usually induces some over-conservatism to compensate the simplification, which is an obstacle to take advantage of the positive characteristics of metallic fuel over the oxide fuel. Therefore, to develop a detailed reactivity feedback model and to remove the over-conservatism in the existing simple model would be the foundation to strengthen the economic and operational competitiveness of a liquid metal-cooled fast reactor. In the present study, the plan for the development of the detailed reactivity feedback model and the methodology to combine the spatial kinetics code with the thermal-hydraulic code have been set up, which are two prerequisites for the evaluation of the detailed reactivity feedback effect. The proposed detailed model is expected to be developed in short-term, thus, easily implemented in the SSC-K code. The development of the spatial kinetics code and the merging it to the detailed thermal-hydraulics code would be achieved in long-term, but finally minimize the uncertainty in the reactivity feedback evaluation by including the detailed thermal-hydraulic information in the reactivity calculation.

  14. Development of a wide band radiative transfer model based on a fast correlated k-distributions generation

    Science.gov (United States)

    Croize, Laurence; Pierro, Jean; Huet, Thierry; Labarre, Luc

    2016-04-01

    MATISSE which acronym means Advanced Modeling of the Earth for Environment and Scenes Simulation is developed by ONERA since the mid 1990's. The code main functionality is to compute spectral or integrated natural background radiance images. Natural backgrounds include the atmosphere, low and high altitude clouds, sea and land. It can also provide specific radiative atmospheric terms as path transmission, path radiances, sky radiances or local illumination around a target point. Spectral bandwidth ranges from 700 to 25000 cm-1 wavenumber (i.e. from 0.4 to 14 μm). As far as molecular absorption is concerned, MATISSE v2.0 is based on a correlated K (CK) model and needs a pre-generation of the k-distributions. This method is very precise but is time consuming and is done as an offline calculation. In answer to the increasing need of rapid radiative transfer codes, the future version of the MATISSE v3.0 will include a fast radiative transfer model at low and at medium spectral resolution. This work aims to develop a fast wide band CK model for the acceleration of radiative transfer calculation. As a first step, a statistical k-distributions fast generator was developed. It allows generating k-distributions from 700 to 25000 cm-1 with a spectral resolution of 1 cm-1 in less than 30 ms(*) for one altitude (that means about three orders of magnitude faster than before). Such speed allows generating k-distributions online. To validate the model, we have compared the obtained transmission spectra with reference spectra using a mix of 6 molecules (H2O, CO2, O3, N2O, CO, CH4) in homogenous atmosphere corresponding to different altitudes from 0 to 105 km. Reference spectra were calculated as the convolution of a spectrum obtained with a line by line model and a gate function of 1 cm-1 wide. An average difference of 3×10-3 % and a standard deviation of 3.3% were typically obtained. As a second step, this method of rapid k-distributions generation is now being coupled with a

  15. Can model observers be developed to reproduce radiologists' diagnostic performances? Our study says not so fast!

    Science.gov (United States)

    Lee, Juhun; Nishikawa, Robert M.; Reiser, Ingrid; Boone, John M.

    2016-03-01

    The purpose of this study was to determine radiologists' diagnostic performances on different image reconstruction algorithms that could be used to optimize image-based model observers. We included a total of 102 pathology proven breast computed tomography (CT) cases (62 malignant). An iterative image reconstruction (IIR) algorithm was used to obtain 24 reconstructions with different image appearance for each image. Using quantitative image feature analysis, three IIRs and one clinical reconstruction of 50 lesions (25 malignant) were selected for a reader study. The reconstructions spanned a range of smooth-low noise to sharp-high noise image appearance. The trained classifiers' AUCs on the above reconstructions ranged from 0.61 (for smooth reconstruction) to 0.95 (for sharp reconstruction). Six experienced MQSA radiologists read 200 cases (50 lesions times 4 reconstructions) and provided the likelihood of malignancy of each lesion. Radiologists' diagnostic performances (AUC) ranged from 0.7 to 0.89. However, there was no agreement among the six radiologists on which image appearance was the best, in terms of radiologists' having the highest diagnostic performances. Specifically, two radiologists indicated sharper image appearance was diagnostically superior, another two radiologists indicated smoother image appearance was diagnostically superior, and another two radiologists indicated all image appearances were diagnostically similar to each other. Due to the poor agreement among radiologists on the diagnostic ranking of images, it may not be possible to develop a model observer for this particular imaging task.

  16. The fast debris evolution model

    Science.gov (United States)

    Lewis, H. G.; Swinerd, G. G.; Newland, R. J.; Saunders, A.

    2009-09-01

    The 'particles-in-a-box' (PIB) model introduced by Talent [Talent, D.L. Analytic model for orbital debris environmental management. J. Spacecraft Rocket, 29 (4), 508-513, 1992.] removed the need for computer-intensive Monte Carlo simulation to predict the gross characteristics of an evolving debris environment. The PIB model was described using a differential equation that allows the stability of the low Earth orbit (LEO) environment to be tested by a straightforward analysis of the equation's coefficients. As part of an ongoing research effort to investigate more efficient approaches to evolutionary modelling and to develop a suite of educational tools, a new PIB model has been developed. The model, entitled Fast Debris Evolution (FADE), employs a first-order differential equation to describe the rate at which new objects ⩾10 cm are added and removed from the environment. Whilst Talent [Talent, D.L. Analytic model for orbital debris environmental management. J. Spacecraft Rocket, 29 (4), 508-513, 1992.] based the collision theory for the PIB approach on collisions between gas particles and adopted specific values for the parameters of the model from a number of references, the form and coefficients of the FADE model equations can be inferred from the outputs of future projections produced by high-fidelity models, such as the DAMAGE model. The FADE model has been implemented as a client-side, web-based service using JavaScript embedded within a HTML document. Due to the simple nature of the algorithm, FADE can deliver the results of future projections immediately in a graphical format, with complete user-control over key simulation parameters. Historical and future projections for the ⩾10 cm LEO debris environment under a variety of different scenarios are possible, including business as usual, no future launches, post-mission disposal and remediation. A selection of results is presented with comparisons with predictions made using the DAMAGE environment model

  17. Development of a fast, accurate radiative transfer model for the Martian atmosphere, past and present

    Science.gov (United States)

    Mischna, Michael A.; Lee, Christopher; Richardson, Mark

    2012-10-01

    We present details of an approach to creating a k-distribution radiative transfer model (KDM) for use in the Martian atmosphere. Such models preserve the accuracy of more rigorous line-by-line models, but are orders of magnitude faster, and can be effectively implemented in 3-D general circulation models. The approach taken here is sufficiently generalized that it can be employed for atmospheres of any arbitrary composition and mass, and demonstrations are provided for simulated atmospheres with a present-day Martian surface pressure (∼6 mb) and a putative thick early Mars atmosphere (∼500 mb), both with and without atmospheric water vapor. KDM-derived absorption coefficients are placed into a look-up table at a set of gridded points in pressure, temperature and atmospheric composition, and a tri-linear interpolation scheme is used to obtain the coefficients appropriate for the local atmospheric conditions. These coefficients may then be used within any of a variety of commonly used flux solvers to obtain atmospheric heating rates. A series of validation tests are performed with the KDM for both present-day and early Mars atmospheric conditions, and the model is compared against several other widely used radiative transfer schemes, including several used in contemporary general circulation models. These validation results identify weaknesses in some other approaches and demonstrate the efficacy of the KDM, providing a rigorous test of these types of models for use in the Martian atmosphere. A demonstration of results obtained by implementing the KDM in a Mars general circulation model is provided.

  18. Enhanced Model for Fast Ignition

    Energy Technology Data Exchange (ETDEWEB)

    Mason, Rodney J. [Research Applications Corporation, Los Alamos, NM (United States)

    2010-10-12

    Laser Fusion is a prime candidate for alternate energy production, capable of serving a major portion of the nation's energy needs, once fusion fuel can be readily ignited. Fast Ignition may well speed achievement of this goal, by reducing net demands on laser pulse energy and timing precision. However, Fast Ignition has presented a major challenge to modeling. This project has enhanced the computer code ePLAS for the simulation of the many specialized phenomena, which arise with Fast Ignition. The improved code has helped researchers to understand better the consequences of laser absorption, energy transport, and laser target hydrodynamics. ePLAS uses efficient implicit methods to acquire solutions for the electromagnetic fields that govern the accelerations of electrons and ions in targets. In many cases, the code implements fluid modeling for these components. These combined features, "implicitness and fluid modeling," can greatly facilitate calculations, permitting the rapid scoping and evaluation of experiments. ePLAS can be used on PCs, Macs and Linux machines, providing researchers and students with rapid results. This project has improved the treatment of electromagnetics, hydrodynamics, and atomic physics in the code. It has simplified output graphics, and provided new input that avoids the need for source code access by users. The improved code can now aid university, business and national laboratory users in pursuit of an early path to success with Fast Ignition.

  19. Assessing the Importance of Nonlinearities in the Development of a Substructure Model for the Wind Turbine CAE Tool FAST: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Damiani, R.; Jonkman, J.; Robertson, A.; Song, H.

    2013-03-01

    Design and analysis of wind turbines are performed using aero-servo-elastic tools that account for the nonlinear coupling between aerodynamics, controls, and structural response. The NREL-developed computer-aided engineering (CAE) tool FAST also resolves the hydrodynamics of fixed-bottom structures and floating platforms for offshore wind applications. This paper outlines the implementation of a structural-dynamics module (SubDyn) for offshore wind turbines with space-frame substructures into the current FAST framework, and focuses on the initial assessment of the importance of structural nonlinearities. Nonlinear effects include: large displacements, axial shortening due to bending, cross-sectional transverse shear effects, etc.

  20. Development of Fast running DNBR Calculation Code

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Hyuk; Seo, K. W.; Kim, S. J.; Hwang, D. H. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2010-10-15

    SMART core adopted a core protection(SCOPS) and a supervising system(SCOMS) to satisfy the SAFDL for AOO and normal operation. Generally, the criteria is limited to the DNBR limit so that the DNBR calculation module is required in the protection and the supervising system of core. There are CPU time limit and calculation robustness as some requirements of the DNBR calculation module in SCOPS and SCOMS caused by hardware limitations. The non-iterative few channel methods are needed to satisfy the requirements. Non-iterative numerical method is similar to the CETOP algorithm originated from ref. 1. The method is known as the non-iterative prediction and correction method. An optimum number of channels for core lumping model is selected as 4- channel which is same channel number of CETOP model. A compensation model of lumped channel is needed to ensure that the 4-channel thermal hydraulic field is nearly equivalent to that field of 1/8-core model that is calculated by MATRA-S. The code called FAST that is fast running DNBR calculation is developed to satisfy the requirements of CPU time and calculation robustness. Present paper is described of characteristics and calculation results of developed FAST code

  1. Development of Gas Turbine Fast Mathematical Model Simulation Module for Software Complex «Electrodin» based on LabVIEW

    Directory of Open Access Journals (Sweden)

    Olga A. Iarmonova

    2013-01-01

    Full Text Available A fast mathematical model simulation module based on LabVIEW graphical programming environment has been developed. The module will be used for gas turbine and electrical power system co-simulation, and for testing automation of gas turbine automatic control systems.

  2. MPACT Fast Neutron Multiplicity System Prototype Development

    Energy Technology Data Exchange (ETDEWEB)

    D.L. Chichester; S.A. Pozzi; J.L. Dolan; M.T. Kinlaw; S.J. Thompson; A.C. Kaplan; M. Flaska; A. Enqvist; J.T. Johnson; S.M. Watson

    2013-09-01

    This document serves as both an FY2103 End-of-Year and End-of-Project report on efforts that resulted in the design of a prototype fast neutron multiplicity counter leveraged upon the findings of previous project efforts. The prototype design includes 32 liquid scintillator detectors with cubic volumes 7.62 cm in dimension configured into 4 stacked rings of 8 detectors. Detector signal collection for the system is handled with a pair of Struck Innovative Systeme 16-channel digitizers controlled by in-house developed software with built-in multiplicity analysis algorithms. Initial testing and familiarization of the currently obtained prototype components is underway, however full prototype construction is required for further optimization. Monte Carlo models of the prototype system were performed to estimate die-away and efficiency values. Analysis of these models resulted in the development of a software package capable of determining the effects of nearest-neighbor rejection methods for elimination of detector cross talk. A parameter study was performed using previously developed analytical methods for the estimation of assay mass variance for use as a figure-of-merit for system performance. A software package was developed to automate these calculations and ensure accuracy. The results of the parameter study show that the prototype fast neutron multiplicity counter design is very nearly optimized under the restraints of the parameter space.

  3. A fast and flexible reactor physics model for simulating neutron spectra and depletion in fast reactors

    Science.gov (United States)

    Recktenwald, Geoff; Deinert, Mark

    2010-03-01

    Determining the time dependent concentration of isotopes within a nuclear reactor core is central to the analysis of nuclear fuel cycles. We present a fast, flexible tool for determining the time dependent neutron spectrum within fast reactors. The code (VBUDS: visualization, burnup, depletion and spectra) uses a two region, multigroup collision probability model to simulate the energy dependent neutron flux and tracks the buildup and burnout of 24 actinides, as well as fission products. While originally developed for LWR simulations, the model is shown to produce fast reactor spectra that show high degree of fidelity to available fast reactor benchmarks.

  4. Recent Developments in CMS Fast Simulation arXiv

    CERN Document Server

    Sekmen, Sezen

    CMS has developed a fast detector simulation package, which serves as a fast and reliable alternative to the detailed GEANT4-based (full) simulation, and enables efficient simulation of large numbers of standard model and new physics events. Fast simulation becomes particularly important with the current increase in the LHC luminosity. Here, I will discuss the basic principles behind the CMS fast simulation framework, and how they are implemented in the different detector components in order to simulate and reconstruct sufficiently accurate physics objects for analysis. I will focus on recent developments in tracking and geometry interface, which improve the flexibility and emulation performance of the framework, and allow a better synchronization with the full simulation. I will then show how these developments have led to an improved agreement of basic analysis objects and event variables between fast and full simulation.

  5. Standardization Bossts SGGCC Fast Development

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    OverviewDuring the development of State Grid Corporation of China (SGCC),standardization work is always highlighted,adhering to standardization planning as a focus in standardization work,centered on technology R&D,grid construction,production & operation,industrial development,etc.,SGCC set up a technology standards system with production process as a main line and featured by "Vertical in the end,lateral to the edge",and launched STATE GRID Corporation of China of Technical Standards System.

  6. Development and evaluation of an efficient soil-atmosphere model (FHAVeT) based on the Ross fast solution of the Richards equation for bare soil conditions

    Science.gov (United States)

    Tinet, A.-J.; Chanzy, A.; Braud, I.; Crevoisier, D.; Lafolie, F.

    2015-02-01

    In agricultural management, a good timing in operations, such as irrigation or sowing, is essential to enhance both economical and environmental performance. To improve such timing, predictive software are of particular interest. Optimal decision-software would require process modules which provide robust, efficient and accurate predictions while being based on a minimal amount of parameters easily available. The objective of this study is to assess the accuracy of a physically based model with high efficiency. To this aim, this paper develops a coupled model with climatic forcing based on the Ross fast solution for Richards' equation, heat transfer and detailed surface energy balance. The present study is limited to bare soil, but the impact of vegetation can be easily included. The developed model, FHAVeT (Fast Hydro Atmosphere Vegetation Temperature), is evaluated against the coupled model based on the Philip and De Vries (1957) description, TEC. The two models were compared for different climatic and soil conditions. Moreover, the model allows using various pedotransfer functions. The FHAVeT model showed better performance in regards to mass balance, mostly below 0.002 m, and generally improved computation time. In order to allow for a more precise comparison, six time windows were selected. The study demonstrated that the FHAVeT behaviour is quite similar to the TEC behaviour except under some dry conditions. The ability of the models to detect the occurrence of soil intermediate water content thresholds with a 1 day tolerance was also evaluated. Both models agreed in more than 90% of the cases.

  7. History of fast reactor fuel development

    Energy Technology Data Exchange (ETDEWEB)

    Kittel, J.H.; Frost, B.R.T. (Argonne National Lab., IL (United States)); Mustelier, J.P. (COGEMA, Velizy-Villacoublay (France))

    1992-01-01

    Most of the first generation of fast reactors that were operated at significant power levels employed solid metal fuels. They were constructed in the United States and United Kingdom in the 1950s and included Experimental Breeder Reactor (EBR)-I and -II operated by Argonne National Laboratory, United States, the Enrico Fermi Reactor operated by the Atomic Power Development Associates, United States and DFR operated by the U.K. Atomic Energy Authority (UKAEA). Their paper tracer pre-development of fast reactor fuel from these early days through the 1980s including ceramic fuels.

  8. Dynamic model of Fast Breeder Test Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Vaidyanathan, G., E-mail: vaidya@igcar.gov.i [Fast Reactor Technology Group, Indira Gandhi Center for Atomic Research, Kalpakkam (India); Kasinathan, N.; Velusamy, K. [Fast Reactor Technology Group, Indira Gandhi Center for Atomic Research, Kalpakkam (India)

    2010-04-15

    Fast Breeder Test Reactor (FBTR) is a 40 M Wt/13.2 MWe sodium cooled reactor operating since 1985. It is a loop type reactor. As part of the safety analysis the response of the plant to various transients is needed. In this connection a computer code named DYNAM was developed to model the reactor core, the intermediate heat exchanger, steam generator, piping, etc. This paper deals with the mathematical model of the various components of FBTR, the numerical techniques to solve the model, and comparison of the predictions of the code with plant measurements. Also presented is the benign response of the plant to a station blackout condition, which brings out the role of the various reactivity feedback mechanisms combined with a gradual coast down of reactor sodium flow.

  9. Fast Newton active appearance models

    NARCIS (Netherlands)

    Kossaifi, Jean; Tzimiropoulos, Georgios; Pantic, Maja

    2014-01-01

    Active Appearance Models (AAMs) are statistical models of shape and appearance widely used in computer vision to detect landmarks on objects like faces. Fitting an AAM to a new image can be formulated as a non-linear least-squares problem which is typically solved using iterative methods. Owing to i

  10. Development of fast scattering model of complex shape target for seminatural tests of onboard proximity radars in real time mode

    Directory of Open Access Journals (Sweden)

    Likhoedenko Andrei K.

    2016-01-01

    Full Text Available Problems of creation of models of real time of complex shape targets on the basis of use of their polygonal models are considered. Formulas for radar cross section of multipoint model of target and power of input signal of onboard radar are described. Technique of semi-natural tests of onboard radar detector on the base of multipoint model of target is proposed. Results of digital simulation of input signals of the onboard radar detector of the target from the aerodynamic target on the basis of their multipoint models are given.

  11. Development of the Circulation Control Flow Scheme Used in the NTF Semi-Span FAST-MAC Model

    Science.gov (United States)

    Jones, Gregory S.; Milholen, William E., II; Chan, David T.; Allan, Brian G.; Goodliff, Scott L.; Melton, Latunia P.; Anders, Scott G.; Carter, Melissa B.; Capone, Francis J.

    2013-01-01

    The application of a circulation control system for high Reynolds numbers was experimentally validated with the Fundamental Aerodynamic Subsonic Transonic Modular Active Control semi-span model in the NASA Langley National Transonic Facility. This model utilized four independent flow paths to modify the lift and thrust performance of a representative advanced transport type of wing. The design of the internal flow paths highlights the challenges associated with high Reynolds number testing in a cryogenic pressurized wind tunnel. Weight flow boundaries for the air delivery system were identified at mildly cryogenic conditions ranging from 0.1 to 10 lbm/sec. Results from the test verified system performance and identified solutions associated with the weight-flow metering system that are linked to internal perforated plates used to achieve flow uniformity at the jet exit.

  12. History of fast reactor fuel development

    Energy Technology Data Exchange (ETDEWEB)

    Kittel, J.H. (Argonne National Lab., IL (United States)); Frost, B.R.T. (Argonne National Lab., IL (United States)); Mustelier, J.P. (COGEMA, Velizy-Villacoublay (France)); Bagley, K.Q. (AEA Reactor Services, Risley (United Kingdom)); Crittenden, G.C. (AEA Reactor Services, Dounreay (United Kingdom)); Dievoet, J. van (Belgonucleaire, Brussels (Belgium))

    1993-09-01

    The first fast breeder eactors, constructed in the 1945-1960 time period, used metallic fuels composed of uranium, plutonium, or their alloys. They were chosen because most existing reactor operating experience had been obtained on metallic fuels and because they provided the highest breeding ratios. Difficulties in obtaining adequate dimensional stability in metallic fuel elements under conditions of high fuel burnup led in the 1960s to the virtual worldwide choice of ceramic fuels. Although ceramic fuels provide lower breeding performance, this objective is no longer an important consideration in most national programs. Mixed uranium and plutonium dioxide became the ceramic fuel that has received the widest use. The more advanced ceramic fuels, mixed uranium and plutonium carbides and nitrides, continue under development. More recently, metal fuel elements of improved design have joined ceramic fuels in achieving goal burnups of 15 to 20 percent. Low-swelling fuel cladding alloys have also been continuously developed to deal with the unexpected problem of void formation in stainless steels subjected to fast neutron irradiation, a phenomenon first observed in the 1960s. (orig.)

  13. SNS EXTRACTION FAST KICKER SYSTEM DEVELOPMENT.

    Energy Technology Data Exchange (ETDEWEB)

    ZHANG,W.; SANDBERG,J.; LAMBIASE,R.; LEE,Y.Y.; LOCKEY,R.; MI,J.; NEHRING,T.; PAI,C.; TSOUPAS,N.; TUOZZOLO,J.; WARBURTON,D.; WEI,J.; RUST,K.; CUTLER,R.

    2003-06-15

    The SNS Extraction Fast Kicker System is a very high power, high repetition rate pulsed power system. It was design and developed at Brookhaven National Laboratory. This system will consist of fourteen identical high voltage, high current modulators, and their auxiliary control and charging systems. The modulators will drive fourteen extraction magnet sections located inside of the SNS accumulator ring. The required kicker field rise time is 200 ns, a pulse flattop of 700 ns, a pulse repetition rate of 60 pulse-per-second. A 2500 Ampere per modulator output is required to reach the extraction kicker magnetic field strength. This design features a Blumlein Pulse-Forming-Network based topology, a low beam impedance termination, a fast current switching thyratron, and low inductance capacitor banks. It has a maximum charging voltage of 50kV, an open circuit output of 100kV, and a designed maximum pulsed current output of 4kA per modulator. The overall system output will be multiple GVA with 60 Pulse-per-second repetition rate. A prototype modulator has been successfully built and tested well above the SNS requirement. The modulator system production is in progress.

  14. Liquid Cryogenic Target Development for Fast Ignition*

    Science.gov (United States)

    Hanson, D. L.; Russell, C.; Vesey, R. A.; Schroen, D. G.; Taylor, J. L.; Back, C. A.; Steinman, D.; Nikroo, A.; Kaae, J. L.; Giraldez, E.; Johnston, R. R.; Youngman, K.

    2007-11-01

    As an alternative to foam-stabilized cryogenic solid D-T fuel layers for indirect-drive fast ignitor targets, which will tend to β-layer to a nonuniform distribution in a reentrant cone geometry [1], we are investigating hemispherical cryogenic fast ignition capsules with a liquid fuel layer confined between a thick outer ablator shell and a thin inner shell [2]. The shape and surface quality of the fuel layer is determined entirely by the characteristics of the bounding shells. In the present design, structural support for the thin (4.5 um) hemispherical GDP inner shell is provided by a mounting ring. Fabrication of stronger thin Be hemi-shells is also being investigated. Technology issues for liquid cryogenic fuel capsule development and progress toward demonstration of a working target will be presented. [1] J.K. Hoffer et al., Fusion Sci. Technol. 50, 15 (2006). [2] D.L. Hanson et al., Fusion Sci. Technol. 49, 500 (2006). *Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy's National Nuclear Security Administration under Contract DE-AC04-94AL85000.

  15. Fast Development Of China's Small Satellite Industry

    Institute of Scientific and Technical Information of China (English)

    Sun Hongjin

    2009-01-01

    @@ China Spacesat Co., Ltd of China Academy of Space Technology (CAST) recently said, along with the successful launch of HJ-1A/B for the environment and disaster monitoring and forecasting small satellite constellation and after years of efforts, small satellite development technology has achieved fruitful results, and the development status has been greatly improved.China's small satellite technology has realized a great-leap-forward in development from a single satellite model to series model, from the satellite program to space industry. China has explored a development road for China's small satellite industrialization, and a modern small satellite development base has resulted.

  16. Fast Quantum Rabi Model with Trapped Ions

    Science.gov (United States)

    Moya-Cessa, Héctor M.

    2016-12-01

    We show how to produce a fast quantum Rabi model with trapped ions. Its importance resides not only in the acceleration of the phenomena that may be achieved with these systems, from quantum gates to the generation of nonclassical states of the vibrational motion of the ion, but also in reducing unwanted effects such as the decay of coherences that may appear in such systems.

  17. Caltech computer scientists develop FAST protocol to speed up Internet

    CERN Multimedia

    2003-01-01

    "Caltech computer scientists have developed a new data transfer protocol for the Internet fast enough to download a full-length DVD movie in less than five seconds. The protocol is called FAST, standing for Fast Active queue management Scalable Transmission Control Protocol" (1 page).

  18. NASA AVOSS Fast-Time Wake Prediction Models: User's Guide

    Science.gov (United States)

    Ahmad, Nash'at N.; VanValkenburg, Randal L.; Pruis, Matthew

    2014-01-01

    The National Aeronautics and Space Administration (NASA) is developing and testing fast-time wake transport and decay models to safely enhance the capacity of the National Airspace System (NAS). The fast-time wake models are empirical algorithms used for real-time predictions of wake transport and decay based on aircraft parameters and ambient weather conditions. The aircraft dependent parameters include the initial vortex descent velocity and the vortex pair separation distance. The atmospheric initial conditions include vertical profiles of temperature or potential temperature, eddy dissipation rate, and crosswind. The current distribution includes the latest versions of the APA (3.4) and the TDP (2.1) models. This User's Guide provides detailed information on the model inputs, file formats, and the model output. An example of a model run and a brief description of the Memphis 1995 Wake Vortex Dataset is also provided.

  19. Evaluation of Fast-Time Wake Vortex Prediction Models

    Science.gov (United States)

    Proctor, Fred H.; Hamilton, David W.

    2009-01-01

    Current fast-time wake models are reviewed and three basic types are defined. Predictions from several of the fast-time models are compared. Previous statistical evaluations of the APA-Sarpkaya and D2P fast-time models are discussed. Root Mean Square errors between fast-time model predictions and Lidar wake measurements are examined for a 24 hr period at Denver International Airport. Shortcomings in current methodology for evaluating wake errors are also discussed.

  20. Characterization and modeling of fast programming bits in flash EEPROM

    Science.gov (United States)

    Nkansah, F.; Hatalis, M.; Olasupo, K.

    2000-11-01

    The effects of flash EEPROM floating gate (FG) morphology on the generation and density of fast programming bits in a 2Mbit flash EEPROM array has been characterized. These fast programming bits exhibit identical subthreshold characteristics similar to that of a normal bit after UV erase, thus establishing that the initial charge stored on the FG of both fast and normal bit is the same. Experimental results clearly indicates that the fast programming phenomena result from an interaction of the programming process with the FG polysilicon microstructure. An in-depth experimentation previously reported, reveals that the FG poly deposition and doping processes are crucial for controlling the desired Fowler-Nordheim tunneling. A correlation is established between the fast bit density observed in the memory arrays, the FG polysilicon grain size and tunneling field enhancement factor μ( Rc). A compact model of the fast programming bit memory threshold voltage as a function of the effective FG polysilicon grain area factor Geff, and tunneling field enhancement factor μ( Rc) has been developed for the first time.

  1. FAST

    DEFF Research Database (Denmark)

    Zuidmeer-Jongejan, Laurian; Fernandez-Rivas, Montserrat; Poulsen, Lars K.

    2012-01-01

    ABSTRACT: The FAST project (Food Allergy Specific Immunotherapy) aims at the development of safe and effective treatment of food allergies, targeting prevalent, persistent and severe allergy to fish and peach. Classical allergen-specific immunotherapy (SIT), using subcutaneous injections with aqu......ABSTRACT: The FAST project (Food Allergy Specific Immunotherapy) aims at the development of safe and effective treatment of food allergies, targeting prevalent, persistent and severe allergy to fish and peach. Classical allergen-specific immunotherapy (SIT), using subcutaneous injections...... with aqueous food extracts may be effective but has proven to be accompanied by too many anaphylactic side-effects. FAST aims to develop a safe alternative by replacing food extracts with hypoallergenic recombinant major allergens as the active ingredients of SIT. Both severe fish and peach allergy are caused...... in depth serological and cellular immune analyses will be performed, allowing identification of novel biomarkers for monitoring treatment efficacy. FAST aims at improving the quality of life of food allergic patients by providing a safe and effective treatment that will significantly lower their threshold...

  2. Fast Charging Electric Vehicle Research & Development Project

    Energy Technology Data Exchange (ETDEWEB)

    Heny, Michael

    2014-03-31

    The research and development project supported the engineering, design and implementation of on-road Electric Vehicle (“EV”) charging technologies. It included development of potential solutions for DC fast chargers (“DCFC”) capable of converting high voltage AC power to the DC power required by EVs. Additional development evaluated solutions related to the packaging of power electronic components and enclosure design, as well as for the design and evaluation of EV charging stations. Research compared different charging technologies to identify optimum applications in a municipal fleet. This project collected EV usage data and generated a report demonstrating that EVs, when supported by adequate charging infrastructure, are capable of replacing traditional internal combustion vehicles in many municipal applications. The project’s period of performance has demonstrated various methods of incorporating EVs into a municipal environment, and has identified three general categories for EV applications: - Short Commute: Defined as EVs performing in limited duration, routine commutes. - Long Commute: Defined as tasks that require EVs to operate in longer daily mileage patterns. - Critical Needs: Defined as the need for EVs to be ready at every moment for indefinite periods. Together, the City of Charlottesville, VA (the “City”) and Aker Wade Power Technologies, LLC (“Aker Wade”) concluded that the EV has a viable position in many municipal fleets but with limited recommendation for use in Critical Needs applications such as Police fleets. The report also documented that, compared to internal combustion vehicles, BEVs have lower vehicle-related greenhouse gas (“GHG”) emissions and contribute to a reduction of air pollution in urban areas. The enhanced integration of EVs in a municipal fleet can result in reduced demand for imported oil and reduced municipal operating costs. The conclusions indicated in the project’s Engineering Report (see

  3. Fast Charging Electric Vehicle Research & Development Project

    Energy Technology Data Exchange (ETDEWEB)

    Heny, Michael

    2014-03-31

    The research and development project supported the engineering, design and implementation of on-road Electric Vehicle (“EV”) charging technologies. It included development of potential solutions for DC fast chargers (“DCFC”) capable of converting high voltage AC power to the DC power required by EVs. Additional development evaluated solutions related to the packaging of power electronic components and enclosure design, as well as for the design and evaluation of EV charging stations. Research compared different charging technologies to identify optimum applications in a municipal fleet. This project collected EV usage data and generated a report demonstrating that EVs, when supported by adequate charging infrastructure, are capable of replacing traditional internal combustion vehicles in many municipal applications. The project’s period of performance has demonstrated various methods of incorporating EVs into a municipal environment, and has identified three general categories for EV applications: Short Commute: Defined as EVs performing in limited duration, routine commutes. - Long Commute: Defined as tasks that require EVs to operate in longer daily mileage patterns. - Critical Needs: Defined as the need for EVs to be ready at every moment for indefinite periods. Together, the City of Charlottesville, VA (the “City”) and Aker Wade Power Technologies, LLC (“Aker Wade”) concluded that the EV has a viable position in many municipal fleets but with limited recommendation for use in Critical Needs applications such as Police fleets. The report also documented that, compared to internal combustion vehicles, BEVs have lower vehicle-related greenhouse gas (“GHG”) emissions and contribute to a reduction of air pollution in urban areas. The enhanced integration of EVs in a municipal fleet can result in reduced demand for imported oil and reduced municipal operating costs. The conclusions indicated in the project’s Engineering Report (see Attachment

  4. Modeling fast and slow earthquakes at various scales.

    Science.gov (United States)

    Ide, Satoshi

    2014-01-01

    Earthquake sources represent dynamic rupture within rocky materials at depth and often can be modeled as propagating shear slip controlled by friction laws. These laws provide boundary conditions on fault planes embedded in elastic media. Recent developments in observation networks, laboratory experiments, and methods of data analysis have expanded our knowledge of the physics of earthquakes. Newly discovered slow earthquakes are qualitatively different phenomena from ordinary fast earthquakes and provide independent information on slow deformation at depth. Many numerical simulations have been carried out to model both fast and slow earthquakes, but problems remain, especially with scaling laws. Some mechanisms are required to explain the power-law nature of earthquake rupture and the lack of characteristic length. Conceptual models that include a hierarchical structure over a wide range of scales would be helpful for characterizing diverse behavior in different seismic regions and for improving probabilistic forecasts of earthquakes.

  5. Model instruments of effective segmentation of the fast food market

    Directory of Open Access Journals (Sweden)

    Mityaeva Tetyana L.

    2013-03-01

    Full Text Available The article presents results of optimisation step-type calculations of economic effectiveness of promotion of fast food with consideration of key parameters of assessment of efficiency of the marketing strategy of segmentation. The article justifies development of a mathematical model on the bases of 3D-presentations and three-dimensional system of management variables. The modern applied mathematical packages allow formation not only of one-dimensional and two-dimensional arrays and analyse links of variables, but also of three-dimensional, besides, the more links and parameters are taken into account, the more adequate and adaptive are results of modelling and, as a result, more informative and strategically valuable. The article shows modelling possibilities that allow taking into account strategies and reactions on formation of the marketing strategy under conditions of entering the fast food market segments.

  6. A distinct metabolic signature predicts development of fasting plasma glucose.

    Science.gov (United States)

    Hische, Manuela; Larhlimi, Abdelhalim; Schwarz, Franziska; Fischer-Rosinský, Antje; Bobbert, Thomas; Assmann, Anke; Catchpole, Gareth S; Pfeiffer, Andreas Fh; Willmitzer, Lothar; Selbig, Joachim; Spranger, Joachim

    2012-02-02

    High blood glucose and diabetes are amongst the conditions causing the greatest losses in years of healthy life worldwide. Therefore, numerous studies aim to identify reliable risk markers for development of impaired glucose metabolism and type 2 diabetes. However, the molecular basis of impaired glucose metabolism is so far insufficiently understood. The development of so called 'omics' approaches in the recent years promises to identify molecular markers and to further understand the molecular basis of impaired glucose metabolism and type 2 diabetes. Although univariate statistical approaches are often applied, we demonstrate here that the application of multivariate statistical approaches is highly recommended to fully capture the complexity of data gained using high-throughput methods. We took blood plasma samples from 172 subjects who participated in the prospective Metabolic Syndrome Berlin Potsdam follow-up study (MESY-BEPO Follow-up). We analysed these samples using Gas Chromatography coupled with Mass Spectrometry (GC-MS), and measured 286 metabolites. Furthermore, fasting glucose levels were measured using standard methods at baseline, and after an average of six years. We did correlation analysis and built linear regression models as well as Random Forest regression models to identify metabolites that predict the development of fasting glucose in our cohort. We found a metabolic pattern consisting of nine metabolites that predicted fasting glucose development with an accuracy of 0.47 in tenfold cross-validation using Random Forest regression. We also showed that adding established risk markers did not improve the model accuracy. However, external validation is eventually desirable. Although not all metabolites belonging to the final pattern are identified yet, the pattern directs attention to amino acid metabolism, energy metabolism and redox homeostasis. We demonstrate that metabolites identified using a high-throughput method (GC-MS) perform well in

  7. Development of imaging techniques for fast neutron radiography in Japan

    CERN Document Server

    Fujine, S; Yoshii, K; Kamata, M; Tamaki, M; Ohkubo, K; Ikeda, Y; Kobayashi, H

    1999-01-01

    Neutron radiography with fast neutron beams (FNR) has been studied at the fast neutron source reactor 'YAYOI' of the University of Tokyo since 1986. Imaging techniques for FNR have been developed for CR-39 track-etch detector, electronic imaging system (television method), direct film method, imaging plate and also fast and thermal neutron concurrent imaging method. The review of FNR imaging techniques and some applications are reported in this paper.

  8. Fast Track Teaching: Beginning the Experiment in Accelerated Leadership Development

    Science.gov (United States)

    Churches, Richard; Hutchinson, Geraldine; Jones, Jeff

    2009-01-01

    This article provides an overview of the development of the Fast Track teaching programme and personalised nature of the training and support that has been delivered. Fast Track teacher promotion rates are compared to national statistics demonstrating significant progression for certain groups, particularly women. (Contains 3 tables and 3 figures.)

  9. Development of multi-dimensional thermal hydraulic modeling using mixing factors for wire wrapped fuel pin bundles with inter-subassembly heat transfer in fast reactors

    Energy Technology Data Exchange (ETDEWEB)

    Nishimura, M.; Kamide, H.; Ohshima, H. [Power Reactor and Nuclear Fuel Development Corp., Oarai, Ibaraki (Japan). Oarai Engineering Center

    1996-10-01

    Temperature distributions in fuel subassemblies of fast reactors interactively affect heat transfer from center to outer region of the core (inter-subassembly heat transfer) and cooling capability of an inter-wrapper flow, as well as maximum cladding temperature. The prediction of temperature distribution in the sub-assembly is, therefore one of the important issues for the reactor safety assessment. To treat the complex phenomena in the core, a multi-dimensional thermal hydraulic analysis is the most promising method. From the studies on the multi-dimensional thermal hydraulic modeling for the fuel sub-assemblies, the modeling have been recommended through the analysis of sodium experiments using driver subassembly test rig PLANDTL-DHX and blanket subassembly test rig CCTL-CFR. Computations of steady states experiments in the test rigs using the above modeling showed quite good agreement to the experimental data. In the present study, the use of this modeling was extended to transient analyses, and its applicability was examined. Firstly, non-dimensional parameters used to determine the mixing factors were modified from the ones based on bundle-averaged values to the ones by local values. Secondly, a new threshold function was derived and introduced to cut off the mixing factor of thermal plumes under inertia force dominant conditions. In the results of this validation, the accuracy was comparable between the modeling and the experimental instrumentation. Thus the present modeling is capable of predicting the thermal hydraulic fields of the wire wrapped fuel pin bundles with inter-subassembly heat transfer under the conditions from rated steady operations to transitions toward natural circulation decay heat removal modes. (J.P.N.)

  10. Fast and Flexible Modelling of Real-Time Systems with RTCP-Nets

    Directory of Open Access Journals (Sweden)

    Marcin Szpyrka

    2004-01-01

    Full Text Available A large number of formalisms has been proposed for real-time systems modelling. However, formal methods are not widely used in industrial software development. Such a situation could be treated as a result of a lack of suitable tools for fast designing of a model, its analysis and modification. RTCP-nets have been defined to facilitate fast modelling of embedded systems incorporating rule-based systems. Computer tools that are being developed for RTCP-nets, use a template mechanism to allow users to design models and manipulate its properties fast and effectively. Both theoretical and practical aspects of RTCP-nets are presented in the paper.

  11. Reservoir management under geological uncertainty using fast model update

    NARCIS (Netherlands)

    Hanea, R.; Evensen, G.; Hustoft, L.; Ek, T.; Chitu, A.; Wilschut, F.

    2015-01-01

    Statoil is implementing "Fast Model Update (FMU)," an integrated and automated workflow for reservoir modeling and characterization. FMU connects all steps and disciplines from seismic depth conversion to prediction and reservoir management taking into account relevant reservoir uncertainty. FMU del

  12. Modelling the inelastic scattering of fast electrons

    Energy Technology Data Exchange (ETDEWEB)

    Allen, L.J., E-mail: lja@unimelb.edu.au [School of Physics, University of Melbourne, Parkville, Victoria 3010 (Australia); D' Alfonso, A.J., E-mail: a.j@dalfonso.com.au [School of Physics, University of Melbourne, Parkville, Victoria 3010 (Australia); Findlay, S.D. [School of Physics, Monash University, Clayton, Victoria 3800 (Australia)

    2015-04-15

    Imaging at atomic resolution based on the inelastic scattering of electrons has become firmly established in the last three decades. Harald Rose pioneered much of the early theoretical work on this topic, in particular emphasising the role of phase and the importance of a mixed dynamic form factor. In this paper we review how the modelling of inelastic scattering has subsequently developed and how numerical implementation has been achieved. A software package μSTEM is introduced, capable of simulating various imaging modes based on inelastic scattering in both scanning and conventional transmission electron microscopy. - Highlights: • Harald Rose was a pioneer of important work on atomic resolution imaging using inelastic scattering. • We review how the modelling of inelastic scattering has subsequently developed and been applied. • A software package μSTEM is introduced, capable of simulating various inelastic imaging modes.

  13. Development of Glassy Carbon Blade for LHC Fast Vacuum Valve

    CERN Document Server

    Coly, P

    2012-01-01

    An unexpected gas inrush in a vacuum chamber leads to the development of a fast pressure wave. It carries small particles that can compromise functionality of sensitive machine systems such as the RF cavities or kickers. In the LHC machine, it has been proposed to protect this sensitive equipment by the installation of fast vacuum valves. The main requirements for the fast valves and in particular for the blade are: fast closure in the 20 ms range, high transparency and melting temperature in case of closure with beam in, dust free material to not contaminate sensitive adjacent elements, and last but not least vacuum compatibility and adequate leak tightness across the blade. In this paper, different designs based on a vitreous carbon blade are presented and a solution is proposed. The main reasons for this material choice are given. The mechanical study of the blade behaviour under dynamic forces is shown.

  14. Fast Nonconvex Model Predictive Control for Commercial Refrigeration

    DEFF Research Database (Denmark)

    Hovgaard, Tobias Gybel; Larsen, Lars F. S.; Jørgensen, John Bagterp

    2012-01-01

    in fewer than 5 or so iterations. We employ a fast convex quadratic programming solver to carry out the iterations, which is more than fast enough to run in real-time. We demonstrate our method on a realistic model, with a full year simulation, using real historical data. These simulations show substantial...

  15. Fast, Automated, Photo realistic, 3D Modeling of Building Interiors

    Science.gov (United States)

    2016-09-12

    These models are used in augmented reality , navigation, and energy simulation applications. State -of- the- art scanning produces accurate pointclouds of...preservation, entertainment, and augmented reality , the demand for both fast and accurate scanning technologies has dramatically increased. In this...With applications such as historical preservation, entertainment, and augmented reality , the demand for both fast and accurate scanning

  16. Modeling Fast Ion Transport in TAE Avalanches in NSTX

    Energy Technology Data Exchange (ETDEWEB)

    Fredrickson, E D; Bell, R E; Darrow, D; Gorelenkov, N N; Kramer, G; Kubota, S; Levinton, F M; Liu, D; Medley, S S; Podesta, M; Tritz, K

    2009-08-17

    Experiments on the National Spherical Torus Experiment [M. Ono, et al., Nucl. Fusion 40 (2000) 557 ] have found strong bursts of Toroidal Alfven Eigenmode (TAE) activity correlated with abrupt drops in the neutron rate. A fairly complete data set offers the opportunity to benchmark the NOVA [C. Z. Cheng, Phys. Reports 211, 1-51 (1992)] and ORBIT [R. B. White and M. S. Chance, Phys. Fluids 27, 2455 (1984)] codes in the low aspect ratio tokamak (ST) geometry. The internal structure of TAE were modeled with NOVA and good agreement is found with measurements made with an array of five fixed-frequency reflectometers. The fast-ion transport resulting from these bursts of multiple TAE were then modeled with the ORBIT code. The simulations are reasonably consistent with the observed drop in neutron rate. While these results represent our best attempts to find agreement, we believe that further refinements in both the simulation of the TAE structure and in the modeling of the fast ion transport are needed. Benchmarking stability codes against present experiments is an important step in developing the predictive capability needed to plan future experiments.

  17. New Symmetries for a Model of Fast Diffusion

    Institute of Scientific and Technical Information of China (English)

    QIN Mao-Chang; XU Xue-Jun; MEI Feng-Xiang

    2004-01-01

    @@ The new symmetries for a mathematical model of fast diffusion are determined. A new system method is given to search for new symmetries of differential equations written in a conserved form, several new symmetry generators and exact solutions are presented.

  18. The Massive Schwinger Model in a Fast Moving Frame

    OpenAIRE

    1998-01-01

    We present a non-perturbative study of the massive Schwinger model. We use a Hamiltonian approach, based on a momentum lattice corresponding to a fast moving reference frame, and equal time quantization.

  19. Fast Algorithms for Model-Based Diagnosis

    Science.gov (United States)

    Fijany, Amir; Barrett, Anthony; Vatan, Farrokh; Mackey, Ryan

    2005-01-01

    Two improved new methods for automated diagnosis of complex engineering systems involve the use of novel algorithms that are more efficient than prior algorithms used for the same purpose. Both the recently developed algorithms and the prior algorithms in question are instances of model-based diagnosis, which is based on exploring the logical inconsistency between an observation and a description of a system to be diagnosed. As engineering systems grow more complex and increasingly autonomous in their functions, the need for automated diagnosis increases concomitantly. In model-based diagnosis, the function of each component and the interconnections among all the components of the system to be diagnosed (for example, see figure) are represented as a logical system, called the system description (SD). Hence, the expected behavior of the system is the set of logical consequences of the SD. Faulty components lead to inconsistency between the observed behaviors of the system and the SD. The task of finding the faulty components (diagnosis) reduces to finding the components, the abnormalities of which could explain all the inconsistencies. Of course, the meaningful solution should be a minimal set of faulty components (called a minimal diagnosis), because the trivial solution, in which all components are assumed to be faulty, always explains all inconsistencies. Although the prior algorithms in question implement powerful methods of diagnosis, they are not practical because they essentially require exhaustive searches among all possible combinations of faulty components and therefore entail the amounts of computation that grow exponentially with the number of components of the system.

  20. Model biases in high-burnup fast reactor simulations

    Energy Technology Data Exchange (ETDEWEB)

    Touran, N.; Cheatham, J.; Petroski, R. [TerraPower LLC, 11235 S.E. 6th St, Bellevue, WA 98004 (United States)

    2012-07-01

    A new code system called the Advanced Reactor Modeling Interface (ARMI) has been developed that loosely couples multiscale, multiphysics nuclear reactor simulations to provide rapid, user-friendly, high-fidelity full systems analysis. Incorporating neutronic, thermal-hydraulic, safety/transient, fuel performance, core mechanical, and economic analyses, ARMI provides 'one-click' assessments of many multi-disciplined performance metrics and constraints that historically require iterations between many diverse experts. The capabilities of ARMI are implemented in this study to quantify neutronic biases of various modeling approximations typically made in fast reactor analysis at an equilibrium condition, after many repetitive shuffles. Sensitivities at equilibrium that result in very high discharge burnup are considered ( and >20% FIMA), as motivated by the development of the Traveling Wave Reactor. Model approximations discussed include homogenization, neutronic and depletion mesh resolution, thermal-hydraulic coupling, explicit control rod insertion, burnup-dependent cross sections, fission product model, burn chain truncation, and dynamic fuel performance. The sensitivities of these approximations on equilibrium discharge burnup, k{sub eff}, power density, delayed neutron fraction, and coolant temperature coefficient are discussed. (authors)

  1. Modeling of Dynamic Fluid Forces in Fast Switching Valves

    DEFF Research Database (Denmark)

    Roemer, Daniel Beck; Johansen, Per; Pedersen, Henrik Clemmensen;

    2015-01-01

    Switching valves experience opposing fluid forces due to movement of the moving member itself, as the surrounding fluid volume must move to accommodate the movement. This movement-induced fluid force may be divided into three main components; the added mass term, the viscous term and the socalled...... history term. For general valve geometries there are no simple solution to either of these terms. During development and design of such switching valves, it is therefore, common practice to use simple models to describe the opposing fluid forces, neglecting all but the viscous term which is determined...... based on shearing areas and venting channels. For fast acting valves the opposing fluid force may retard the valve performance significantly, if appropriate measures are not taken during the valve design. Unsteady Computational Fluid Dynamics (CFD) simulations are available to simulate the total fluid...

  2. Slow and fast development in ladybirds: occurrence, effects and significance

    Directory of Open Access Journals (Sweden)

    G. Mishra

    2012-05-01

    Full Text Available Developmental and growth rates are known to vary in response to genetic, developmental, physiological and environmental factors. However, developmental variations that exist within a cohort under any constant rearing condition are not so well investigated. A few such prominent polymorphisms have been studied, but not the subtle ones. The current study investigates the presence of such varying rates of development, slow and fast, in a cohort reared under constant conditions in two ladybirds, Cheilomenes sexmaculata and Propylea dissecta. Our results reveal slow and fast developers in the cohorts of each species and the ratio of slow and fast developers was similar. Slow developers showed a female biased sex ratio. The two developmental variants differed significantly in juvenile duration only in the first instar and the pupal stage, though variations in developmental time were observed in all stages. Fecundity was higher in slow developers, but developmental rates did not affect egg viability. The similar ratio in both ladybirds indicates it to be a result of either presence of a constant ratio across species or an effect of the similar rearing environment.

  3. A fast collocation method for a variable-coefficient nonlocal diffusion model

    Science.gov (United States)

    Wang, Che; Wang, Hong

    2017-02-01

    We develop a fast collocation scheme for a variable-coefficient nonlocal diffusion model, for which a numerical discretization would yield a dense stiffness matrix. The development of the fast method is achieved by carefully handling the variable coefficients appearing inside the singular integral operator and exploiting the structure of the dense stiffness matrix. The resulting fast method reduces the computational work from O (N3) required by a commonly used direct solver to O (Nlog ⁡ N) per iteration and the memory requirement from O (N2) to O (N). Furthermore, the fast method reduces the computational work of assembling the stiffness matrix from O (N2) to O (N). Numerical results are presented to show the utility of the fast method.

  4. Development of natural gum based fast disintegrating tablets of glipizide

    Directory of Open Access Journals (Sweden)

    Antesh Kumar Jha

    2012-01-01

    Full Text Available Dysphagia and risk of choking are leading causes of patient non-compliance in the self-administration of conventional tablets. To overcome these limitations of conventional tablets fast-disintegrating tablets were developed, using natural gums. Natural gums were evaluated for bulk swelling capacity. Powder mix containing natural gums and glipizide was evaluated for water sorption, swelling index and capillary action. For faster onset and immediate hypoglycemic action, the fast disintegrating tablets were prepared with various types of natural gums using the direct compression technique. Formulations containing guar gum disintegrated within a minute and fulfilled the official requirements for dispersible tablets. As the amount of guar gum increased, the friability increased and hardness decreased, resulting in a shorter wetting and disintegration time. Gum acacia and gum tragacanth did the opposite. The glipizide-loaded fast disintegrating tablet prepared with 18 mg of guar gum gave a friability of 0.46 ± 0.02%, content uniformity of 99.34 ± 0.82%, drug content of 99.15 ± 1.16%, wetting time of 39.0 ± 1.04 sec, hardness of 5.70 ± 1.41 Kg and disintegration time less than 30 sec, suggesting that it was a practical product with a good tablet property. In conclusion, natural gum based patient-friendly fast disintegrating tablets of glipizide can be successfully formulated.

  5. Gompertz kinetics model of fast chemical neurotransmission currents.

    Science.gov (United States)

    Easton, Dexter M

    2005-10-01

    At a chemical synapse, transmitter molecules ejected from presynaptic terminal(s) bind reversibly with postsynaptic receptors and trigger an increase in channel conductance to specific ions. This paper describes a simple but accurate predictive model for the time course of the synaptic conductance transient, based on Gompertz kinetics. In the model, two simple exponential decay terms set the rates of development and decline of transmitter action. The first, r, triggering conductance activation, is surrogate for the decelerated rate of growth of conductance, G. The second, r', responsible for Y, deactivation of the conductance, is surrogate for the decelerated rate of decline of transmitter action. Therefore, the differential equation for the net conductance change, g, triggered by the transmitter is dg/dt=g(r-r'). The solution of that equation yields the product of G(t), representing activation, and Y(t), which defines the proportional decline (deactivation) of the current. The model fits, over their full-time course, published records of macroscopic ionic current associated with fast chemical transmission. The Gompertz model is a convenient and accurate method for routine analysis and comparison of records of synaptic current and putative transmitter time course. A Gompertz fit requiring only three independent rate constants plus initial current appears indistinguishable from a Markov fit using seven rate constants.

  6. Chinese RE Performance Materials on the Fast Developing Way (Continued)

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ (2) Other Magnetic Materials RE Giant Magnetostrictive Materials (GMM) Research of GMM in China started since 1980s but developed rapidly. The products can be produced in batches today. However, application of such materials in apparatus is laggard than developed countries. GMM materials are mainly applied in step motors, linear actuators, ultrasonic systems,sonar systems, valves, precise controls, active vibration damping etc. It is estimated that the near 10 years will be the fast developing period of global GMM market. Global production of GMM rnaterials during 1989 to 2005 is listed in Table 3.

  7. Quark Nova Model for Fast Radio Bursts

    CERN Document Server

    Shand, Zachary; Koning, Nico; Ouyed, Rachid

    2015-01-01

    FRBs are puzzling, millisecond, energetic radio transients with no discernible source; observations show no counterparts in other frequency bands. The birth of a quark star from a parent neutron star experiencing a quark nova - previously thought undetectable when born in isolation - provides a natural explanation for the emission characteristics of FRBs. The generation of unstable r-process elements in the quark nova ejecta provides millisecond exponential injection of electrons into the surrounding strong magnetic field at the parent neutron star's light cylinder via $\\beta$-decay. This radio synchrotron emission has a total duration of hundreds of milliseconds and matches the observed spectrum while reducing the inferred dispersion measure by approximately 200 cm$^{-3}$ pc. The model allows indirect measurement of neutron star magnetic fields and periods in addition to providing astronomical measurements of $\\beta$-decay chains of unstable neutron rich nuclei. Using this model, we can calculate expected FR...

  8. Fast 3-D large-scale gravity and magnetic modeling using unstructured grids and an adaptive multilevel fast multipole method

    Science.gov (United States)

    Ren, Zhengyong; Tang, Jingtian; Kalscheuer, Thomas; Maurer, Hansruedi

    2017-01-01

    A novel fast and accurate algorithm is developed for large-scale 3-D gravity and magnetic modeling problems. An unstructured grid discretization is used to approximate sources with arbitrary mass and magnetization distributions. A novel adaptive multilevel fast multipole (AMFM) method is developed to reduce the modeling time. An observation octree is constructed on a set of arbitrarily distributed observation sites, while a source octree is constructed on a source tetrahedral grid. A novel characteristic is the independence between the observation octree and the source octree, which simplifies the implementation of different survey configurations such as airborne and ground surveys. Two synthetic models, a cubic model and a half-space model with mountain-valley topography, are tested. As compared to analytical solutions of gravity and magnetic signals, excellent agreements of the solutions verify the accuracy of our AMFM algorithm. Finally, our AMFM method is used to calculate the terrain effect on an airborne gravity data set for a realistic topography model represented by a triangular surface retrieved from a digital elevation model. Using 16 threads, more than 5800 billion interactions between 1,002,001 observation points and 5,839,830 tetrahedral elements are computed in 453.6 s. A traditional first-order Gaussian quadrature approach requires 3.77 days. Hence, our new AMFM algorithm not only can quickly compute the gravity and magnetic signals for complicated problems but also can substantially accelerate the solution of 3-D inversion problems.

  9. 2-D Electromagnetic Model of Fast-Ramping Superconducting Magnets

    CERN Document Server

    Auchmann, B; Kurz, S; Russenschuck, Stephan

    2006-01-01

    Fast-ramping superconducting (SC) accelerator magnets are the subject of R&D efforts by magnet designers at various laboratories. They require modifications of magnet design tools such as the ROXIE program at CERN, i.e. models of dynamic effects in superconductors need to be implemented and validated. In this paper we present the efforts towards a dynamic 2-D simulation of fast-ramping SC magnets with the ROXIE tool. Models are introduced and simulation results are compared to measurements of the GSI001 magnet of a GSI test magnet constructed and measured at BNL.

  10. Modeling the Performance of Fast Mulipole Method on HPC platforms

    KAUST Repository

    Ibeid, Huda

    2012-04-06

    The current trend in high performance computing is pushing towards exascale computing. To achieve this exascale performance, future systems will have between 100 million and 1 billion cores assuming gigahertz cores. Currently, there are many efforts studying the hardware and software bottlenecks for building an exascale system. It is important to understand and meet these bottlenecks in order to attain 10 PFLOPS performance. On applications side, there is an urgent need to model application performance and to understand what changes need to be made to ensure continued scalability at this scale. Fast multipole methods (FMM) were originally developed for accelerating N-body problems for particle based methods. Nowadays, FMM is more than an N-body solver, recent trends in HPC have been to use FMMs in unconventional application areas. FMM is likely to be a main player in exascale due to its hierarchical nature and the techniques used to access the data via a tree structure which allow many operations to happen simultaneously at each level of the hierarchy. In this thesis , we discuss the challenges for FMM on current parallel computers and future exasclae architecture. Furthermore, we develop a novel performance model for FMM. Our ultimate aim of this thesis is to ensure the scalability of FMM on the future exascale machines.

  11. Development of fuels and structural materials for fast breeder reactors

    Indian Academy of Sciences (India)

    Baldev Raj; S L Mannan; P R Vasudeva Rao; M D Mathew

    2002-10-01

    Fast breeder reactors (FBRs) are destined to play a crucial role inthe Indian nuclear power programme in the foreseeable future. FBR technology involves a multi-disciplinary approach to solve the various challenges in the areas of fuel and materials development. Fuels for FBRs have significantly higher concentration of fissile material than in thermal reactors, with a matching increase in burn-up. The design of the fuel is an important aspect which has to be optimised for efficient, economic and safe production of power. FBR components operate under hostile and demanding environment of high neutron flux, liquid sodium coolant and elevated temperatures. Resistance to void swelling, irradiation creep, and irradiation embrittlement are therefore major considerations in the choice of materials for the core components. Structural and steam generator materials should have good resistance to creep, low cycle fatigue, creep-fatigue interaction and sodium corrosion. The development of carbide fuel and structural materials for the Fast Breeder Test Reactor at Kalpakkam was a great technological challenge. At the Indira Gandhi Centre for Atomic Research (IGCAR), advanced research facilities have been established, and extensive studies have been carried out in the areas of fuel and materials development. This has laid the foundation for the design and development of a 500 MWe Prototype Fast Breeder Reactor. Highlights of some of these studies are discussed in this paper in the context of our mission to develop and deploy FBR technology for the energy security of India in the 21st century.

  12. Electron emission resulting from fast ion impact on thin metal foils: Implications of these data for development of track structure models

    Energy Technology Data Exchange (ETDEWEB)

    DuBois, R.D.; Drexler, C.G.

    1993-04-01

    Experimental information useful in improving and testing theoretical models of energy deposition and redistribution in particle-condensed phase media is discussed. An overview of information available from previous, and ongoing, studies of the electron emission from thin foils is presented and the need for doubly differential electron energy and angular distribution data stressed. Existing data are used to demonstrate that precisely known, and controllable, surface and bulk conditions of the condensed-phase media are required for experimental studies of this type. Work in progress and improvements planned for future studies at the Pacific Northwest Laboratory are outlined.

  13. Fast Cherenkov model of optical photons generation and transportation

    CERN Document Server

    The ATLAS collaboration

    2017-01-01

    This note describes the technical details of Fast Cherenkov model of optical photons generation and transportation: in particular, the mechanism of Cherenkov photons transportation through the straight bar geometry. As an example of usage, the implemetation of the method inside Quartic detector simulation in GEANT4 will be presented and compared to the nominal results.

  14. solveME: fast and reliable solution of nonlinear ME models

    DEFF Research Database (Denmark)

    Yang, Laurence; Ma, Ding; Ebrahim, Ali

    2016-01-01

    reconstructions (M models), are multiscale, and growth maximization is a nonlinear programming (NLP) problem, mainly due to macromolecule dilution constraints. Results: Here, we address these computational challenges. We develop a fast and numerically reliable solution method for growth maximization in ME models...

  15. Development of the fast steering secondary mirror assembly of GMT

    Science.gov (United States)

    Lee, Sungho; Cho, Myung K.; Park, Chan; Han, Jeong-Yeol; Jeong, Ueejeong; Yoon, Yang-noh; Song, Je Heon; Park, Byeong-Gon; Dribusch, Christoph; Park, Won Hyun; Jun, Youra; Yang, Ho-Soon; Moon, Il-Kwon; Oh, Chang Jin; Kim, Ho-Sang; Lee, Kyoung-Don; Bernier, Robert; Alongi, Chris; Rakich, Andrew; Gardner, Paul; Dettmann, Lee; Rosenthal, Wylie

    2016-07-01

    The Giant Magellan Telescope (GMT) will be featured with two Gregorian secondary mirrors, an adaptive secondary mirror (ASM) and a fast-steering secondary mirror (FSM). The FSM has an effective diameter of 3.2 m and built as seven 1.1 m diameter circular segments, which are conjugated 1:1 to the seven 8.4m segments of the primary. Each FSM segment contains a tip-tilt capability for fine co-alignment of the telescope sub-apertures and fast guiding to attenuate telescope wind shake and mount control jitter. This tip-tilt capability thus enhances performance of the telescope in the seeing limited observation mode. As the first stage of the FSM development, Phase 0 study was conducted to develop a program plan detailing the design and manufacturing process for the seven FSM segments. The FSM development plan has been matured through an internal review by the GMTO-KASI team in May 2016 and fully assessed by an external review in June 2016. In this paper, we present the technical aspects of the FSM development plan.

  16. MACULA: Fast Modeling of Rotational Modulations of Spotty Stars

    Science.gov (United States)

    Kipping, David

    2015-08-01

    Rotational modulations are frequently observed on stars observed by photometry surveys such as Kepler, with periodicities ranging from days to months and amplitudes of sub-parts-per-million to several percent. These variations may be studied to reveal important stellar properties such as rotational periods, inclinations and gradients of differential rotation. However, inverting the disk-integrated flux into a solution for spot number, sizes, contrasts, etc is highly degenerate and thereby necessitating an exhaustive search of the parameter space. In recognition of this, the software MACULA is designed to be a fast forward model of circular, grey spots on rotating stars, including effects such as differential rotation, spot evolution and even spot penumbra/umbra. MACULA seeks to achieve computational efficiency by using a wholly analytic description of the disk-integrated flux, which is described in Kipping (2012), leading to a computational improvement of three orders-of-magnitude over its numerical counterparts. As part of the hack day, I'll show how to simulate light curves with MACULA and provide examples with visualizations. I will also discuss the on-going development of the code, which will head towards modeling spot crossing events and radial velocity jitter and I encourage discussions amongst the participants on analytic methods to this end.

  17. Modelling of Moving Coil Actuators in Fast Switching Valves Suitable for Digital Hydraulic Machines

    DEFF Research Database (Denmark)

    Nørgård, Christian; Roemer, Daniel Beck; Bech, Michael Møller

    2015-01-01

    The efficiency of digital hydraulic machines is strongly dependent on the valve switching time. Recently, fast switching have been achieved by using a direct electromagnetic moving coil actuator as the force producing element in fast switching hydraulic valves suitable for digital hydraulic...... machines. Mathematical models of the valve switching, targeted for design optimisation of the moving coil actuator, are developed. A detailed analytical model is derived and presented and its accuracy is evaluated against transient electromagnetic finite element simulations. The model includes...... an estimation of the eddy currents generated in the actuator yoke upon current rise, as they may have significant influence on the coil current response. The analytical model facilitates fast simulation of the transient actuator response opposed to the transient electro-magnetic finite element model which...

  18. System of Modelling and Calculation Analysis of Neutron- Physical Experiments at Fast Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Moiseyev, A.V. [SSC RF - IPPE, 1 Bondarenko Square, Obninsk, Kaluga Region 249033 (Russian Federation)

    2008-07-01

    There is an actual task on storage, processing and analysis of the unique experimental data received on power fast reactors for their subsequent use in projects of fast reactors of new (4.) generation. For modeling and carrying out analysis of experiments the integrated computing system MODEXSYS has been developed. In this system the mechanism for consecutive calculation of a fast reactor states with the detailed description of its components is created. The system includes the database describing fast reactor states, results of neutron-physical characteristics measurements at fast reactor, calculation and benchmark models of experiments and calculation results. In system convenient search means and the special graphics shell are provided. It has Interfaces for processing of calculation results and their analysis. MODEXSYS system has been applied for analysis of three types of experiments at fast reactor: k{sub eff}, control rod worth and energy release distribution. The most important results of this analysis are described. Application of MODEXSYS system will raise accuracy and reliability of forecasting of fast reactors neutron-physical characteristics; for BN-600 reactor recommended level of accuracy is resulted. (authors)

  19. Developments of fast emittance monitors for ion sources at RCNP

    Science.gov (United States)

    Yorita, T.; Hatanaka, K.; Fukuda, M.; Shimada, K.; Yasuda, Y.; Saito, T.; Tamura, H.; Kamakura, K.

    2016-02-01

    Recently, several developments of low energy beam transport line and its beam diagnostic systems have been performed to improve the injection efficiency of ion beam to azimuthally varying field cyclotron at Research Center for Nuclear Physics, Osaka University. One of those is the fast emittance monitor which can measure within several seconds for the efficient beam development and a Pepper-Pot Emittance Monitor (PPEM) has been developed. The PPEM consists of pepper-pot mask, multichannel plate, fluorescent screen, mirror, and CCD camera. The CCD image is taken via IEEE1394b to a personal computer and analyzed immediately and frequently, and then real time measurement with about 2 Hz has been achieved.

  20. Developments of fast emittance monitors for ion sources at RCNP

    Energy Technology Data Exchange (ETDEWEB)

    Yorita, T., E-mail: yorita@rcnp.osaka-u.ac.jp; Hatanaka, K.; Fukuda, M.; Shimada, K.; Yasuda, Y.; Saito, T.; Tamura, H.; Kamakura, K. [Research Center for Nuclear Physics (RCNP), Osaka University, Osaka 567-0047 (Japan)

    2016-02-15

    Recently, several developments of low energy beam transport line and its beam diagnostic systems have been performed to improve the injection efficiency of ion beam to azimuthally varying field cyclotron at Research Center for Nuclear Physics, Osaka University. One of those is the fast emittance monitor which can measure within several seconds for the efficient beam development and a Pepper-Pot Emittance Monitor (PPEM) has been developed. The PPEM consists of pepper-pot mask, multichannel plate, fluorescent screen, mirror, and CCD camera. The CCD image is taken via IEEE1394b to a personal computer and analyzed immediately and frequently, and then real time measurement with about 2 Hz has been achieved.

  1. Development of guidelines for inelastic analysis in design of fast reactor components

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, Kyotada [Japan Atomic Energy Agency (JAEA), 4002, Narita, O-arai, Ibaraki 311-1393 (Japan); Kasahara, Naoto [Japan Atomic Energy Agency (JAEA), 4002, Narita, O-arai, Ibaraki 311-1393 (Japan)], E-mail: kasahara.naoto@jaea.go.jp; Morishita, Masaki [Japan Atomic Energy Agency (JAEA), 4002, Narita, O-arai, Ibaraki 311-1393 (Japan); Shibamoto, Hiroshi; Inoue, Kazuhiko [The Japan Atomic Power Company, Dispatched to JAEA, 4002, Narita, O-arai, Ibaraki 311-1393 (Japan); Nakayama, Yasunari [Kawasaki Heavy Industries, Ltd., 1-1, Kawasaki, Akashi, Hyogo 673-8666 (Japan)

    2008-02-15

    The interim guidelines for the application of inelastic analysis to design of fast reactor components were developed. These guidelines are referred from 'Elevated Temperature Structural Design Guide for Commercialized Fast Reactor (FDS)'. The basic policies of the guidelines are more rational predictions compared with elastic analysis approach and a guarantee of conservative results for design conditions. The guidelines recommend two kinds of constitutive equations to estimate strains conservatively. They also provide the methods for modeling load histories and estimating fatigue and creep damage based on the results of inelastic analysis. The guidelines were applied to typical design examples and their results were summarized as exemplars to support users.

  2. Assessment of simpler calibration models in the development and validation of a fast postmortem multi-analyte LC-QTOF quantitation method in whole blood with simultaneous screening capabilities using SWATH acquisition.

    Science.gov (United States)

    Elmiger, Marco P; Poetzsch, Michael; Steuer, Andrea E; Kraemer, Thomas

    2017-08-29

    In postmortem toxicology, fast methods can provide a triage to avoid unnecessary autopsies. Usually, this requires multiple qualitative and quantitative analytical methods. The aim of the present study was to develop a postmortem LC-QTOF method for simultaneous screening and quantitation using easy sample preparation and reduced alternative calibration models. Hence, a method for 24 highly relevant substances in forensic toxicology was fully validated using the following calibration models: one-point external, one-point internal via corresponding deuterated standards, multi-point external daily calibration, and multi-point external weekly calibration. Two hundred microliters of postmortem blood were spiked with internal deuterated standard mixture and extracted by acetonitrile protein precipitation. Analysis was performed on a Sciex 6600 QTOF instrument with ESI+ mode using data-independent acquisition (DIA) namely sequential window acquisition of all theoretical mass spectra (SWATH). Validation of the different calibration models included selectivity, autosampler stability, recovery, matrix effects, accuracy, and precision for 24 substances. In addition, corresponding deuterated analogs of 52 substances were included to the internal standard mix for semi-quantitative concentration assessment. The simple protein precipitation provided recoveries higher than 55 and 75% for all analytes at low and high concentrations, respectively. Accuracy and precision criteria (bias and imprecision ± 15 and ± 20% near the limit of quantitation) were fulfilled by the different calibration models for most analytes. The validated method was successfully applied to more than 100 authentic postmortem samples and 3 proficiency tests. Furthermore, the one-point internal calibration via corresponding deuterated standard proved to be a considerably time saving technique for 76 analytes. Graphical abstract One-point and multi-point calibration and the resulting beta

  3. FAST: A combined NOC and transient fuel model for CANDU fuel

    Energy Technology Data Exchange (ETDEWEB)

    Prudil, A.; Lewis, B.J.; Chan, P.K., E-mail: Paul.Chan@rmc.ca [Royal Military College of Canada, Dept. of Chemistry and Chemical Engineering, Kingston, Ontario (Canada); Baschuk, J.J. [Atomic Energy of Canada Limited, Chalk River, Ontario (Canada)

    2013-07-01

    The Fuel And Sheath modelling Tool (FAST) is a fuel performance code that is being developed for both normal and transient operating conditions. FAST includes models for heat generation and transport, thermal-expansion, elastic strain, densification, fission product swelling, pellet relocation, contact, grain growth, fission gas release, gas and coolant pressure and sheath creep. These models have been implemented using the Comsol finite-element platform. The equations are solved on a two-dimensional (radial-axial) geometry of a fuel pellet and sheath. FAST has undergone a proof of concept validation against experimental data and comparison to the ELESTRES and ELOCA fuel performance codes. The results show excellent agreement with experimental measurements and the above stated IST- codes. (author)

  4. A fast model for mean and turbulent wind characteristics over terrain with mixed surface roughness

    DEFF Research Database (Denmark)

    Astrup, P.; Mikkelsen, T.; Jensen, N.O.

    1997-01-01

    The real-time near-range atmospheric model chain in RODOS already includes the fast spectral LINCOM code, which was originally developed by Rise for modelling the mean wind fields over hilly, but otherwise homogeneous, terrain. Its output is used as a wind field driver for the dispersion model...... of arrival of radioactive clouds traversing, for instance, a land/water/land surface, and (2) for calculation of the turbulent shear stress, and thereby the scaling parameters, over mixed terrain....

  5. Continuous Evaluation of Fast Processes in Climate Models Using Arm Measurements

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Minghua [Stony Brook Univ., NY (United States)

    2015-01-02

    Under the support of this grant, we investigated the fast process of interaction of clouds, shallow convection, and boundary layer turbulence and their parameterizations. Main accomplishments involve two things. One is the understanding of the physical mechanisms of low cloud feedbacks; the second is the development and evaluation of convection and cloud parameterizations in climate models.

  6. Network Traffic Generator Model for Fast Network-on-Chip Simulation

    DEFF Research Database (Denmark)

    2008-01-01

    For Systems-on-Chip (SoCs) development, a predominant part of the design time is the simulation time. Performance evaluation and design space exploration of such systems in bit- and cycle-true fashion is becoming prohibitive. We propose a traffic generation (TG) model that provides a fast...

  7. Research and Development Roadmaps for Liquid Metal Cooled Fast Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Kim, T. K. [Argonne National Lab. (ANL), Argonne, IL (United States); Grandy, C. [Argonne National Lab. (ANL), Argonne, IL (United States); Natesan, K. [Argonne National Lab. (ANL), Argonne, IL (United States); Sienicki, J. [Argonne National Lab. (ANL), Argonne, IL (United States); Hill, R. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2017-04-20

    The United States Department of Energy (DOE) commissioned the development of technology roadmaps for advanced (non-light water reactor) reactor concepts to help focus research and development funding over the next five years. The roadmaps show the research and development needed to support demonstration of an advanced (non-LWR) concept by the early 2030s, consistent with DOE’s Vision and Strategy for the Development and Deployment of Advanced Reactors. The intent is only to convey the technical steps that would be required to achieve such a goal; the means by which DOE will determine whether to invest in specific tasks will be treated separately. The starting point for the roadmaps is the Technical Readiness Assessment performed as part of an Advanced Test and Demonstration Reactor study released in 2016. The roadmaps were developed based upon a review of technical reports and vendor literature summarizing the technical maturity of each concept and the outstanding research and development needs. Critical path tasks for specific systems were highlighted on the basis of time and resources needed to complete the tasks and the importance of the system to the performance of the reactor concept. The roadmaps are generic, i.e. not specific to a particular vendor’s design but vendor design information may have been used as representative of the concept family. In the event that both near-term and more advanced versions of a concept are being developed, either a single roadmap with multiple branches or separate roadmaps for each version were developed. In each case, roadmaps point to a demonstration reactor (engineering or commercial) and show the activities that must be completed in parallel to support that demonstration in the 2030-2035 window. This report provides the roadmaps for two fast reactor concepts, the Sodium-cooled Fast Reactor (SFR) and the Lead-cooled Fast Reactor (LFR). The SFR technology is mature enough for commercial demonstration by the early 2030s

  8. Case-Based Reasoning(CBR) Model for Ultra-Fast Cooling in Plate Mill

    Institute of Scientific and Technical Information of China (English)

    HU Xiao,WANG Zhaodong,; WANG Guodong

    2014-01-01

    New generation thermo-mechanical control process(TMCP) based on ultra-fast cooling is being widely adopted in plate mill to product high-performance steel material at low cost. Ultra-fast cooling system is complex because of optimizing the temperature control error generated by heat transfer mathematical model and process parameters. In order to simplify the system and improve the temperature control precision in ultra-fast cooling process, several existing models of case-based reasoning(CBR) model are reviewed. Combining with ultra-fast cooling process, a developed R5 CBR model is proposed, which mainly improves the case representation, similarity relation and retrieval module. Certainty factor is defined in semantics memory unit of plate case which provides not only internal data reliability but also product performance reliability. Similarity relation is improved by defined power index similarity membership function. Retrieval process is simplified and retrieval efficiency is improved apparently by windmill retrieval algorithm. The proposed CBR model is used for predicting the case of cooling strategy and its capability is superior to traditional process model. In order to perform comprehensive investigations on ultra-fast cooling process, different steel plates are considered for the experiment. The validation experiment and industrial production of proposed CBR model are carried out, which demonstrated that finish cooling temperature(FCT) error is controlled within±25℃ and quality rate of product is more than 97%. The proposed CBR model can simplify ultra-fast cooling system and give quality performance for steel product.

  9. Case-based reasoning(CBR) model for ultra-fast cooling in plate mill

    Science.gov (United States)

    Hu, Xiao; Wang, Zhaodong; Wang, Guodong

    2014-11-01

    New generation thermo-mechanical control process(TMCP) based on ultra-fast cooling is being widely adopted in plate mill to product high-performance steel material at low cost. Ultra-fast cooling system is complex because of optimizing the temperature control error generated by heat transfer mathematical model and process parameters. In order to simplify the system and improve the temperature control precision in ultra-fast cooling process, several existing models of case-based reasoning(CBR) model are reviewed. Combining with ultra-fast cooling process, a developed R5 CBR model is proposed, which mainly improves the case representation, similarity relation and retrieval module. Certainty factor is defined in semantics memory unit of plate case which provides not only internal data reliability but also product performance reliability. Similarity relation is improved by defined power index similarity membership function. Retrieval process is simplified and retrieval efficiency is improved apparently by windmill retrieval algorithm. The proposed CBR model is used for predicting the case of cooling strategy and its capability is superior to traditional process model. In order to perform comprehensive investigations on ultra-fast cooling process, different steel plates are considered for the experiment. The validation experiment and industrial production of proposed CBR model are carried out, which demonstrated that finish cooling temperature(FCT) error is controlled within ±25°C and quality rate of product is more than 97%. The proposed CBR model can simplify ultra-fast cooling system and give quality performance for steel product.

  10. Achieving Fast Reconnection in Resistive MHD Models via Turbulent Means

    CERN Document Server

    Lapenta, Giovanni

    2011-01-01

    Astrophysical fluids are generally turbulent and this preexisting turbulence must be taken into account for the models of magnetic reconnection which are attepmted to be applied to astrophysical, solar or heliospheric environments. In addition, reconnection itself induces turbulence which provides an important feedback on the reconnection process. In this paper we discuss both theoretical model and numerical evidence that magnetic reconnection gets fast in the approximation of resistive MHD. We consider the relation between the Lazarian & Vishniac turbulent reconnection theory and Lapenta's numerical experiments testifying of the spontaneous onset of turbulent reconnection in systems which are initially laminar.

  11. 用于池式快堆系统分析的钠池三维模型开发%Development of Three-Dimensional Sodium Pool Model for System Analysis of Pool-Type Liquid Metal Fast Breeder Reactor

    Institute of Scientific and Technical Information of China (English)

    隋丹婷; 陆道纲; 张盼

    2012-01-01

    由于池式快堆钠池内的热工水力学特性对反应堆的安全运行有重要影响,本文采用基于交错网格的SIMPLE算法开发直角坐标系和柱坐标系下钠池三维计算软件.应用CFX软件进行验证之后,完成了三维流场分析程序与系统分析软件SAC-CFR的耦合,并用耦合后的程序分析日本文殊快堆45%功率稳态运行工况上腔室内的流场分布,初步验证了堆芯上腔三维化的SAC-CFR用于系统分析的有效性,为进一步开发事故模型、非能动余热排出系统模型做准备.%As the thermal-hydraulic characteristic in sodium pool is crucial for safety operation of liquid metal fast breeder reactor (LMFBR), a three-dimensional sodium pool thermal-hydraulic analysis code was developed based on SIMPLE algorithm on stagger grid under Cartesian coordinates and cylindrical coordinates. After the validation with CFX, coupling between the analysis code and SAC-CFR was completed) and then the coupled code was applied to the flow field analysis in upper plenum of Monju Plant at 45% thermal power steady-state operation condition, which preliminary shows the effectiveness of the system analysis with coupled code and makes preparations for further development of accident analysis model and passive residual heat removal system.

  12. Assessing Cognitive Processes with Diffusion Model Analyses: A Tutorial based on fast-dm-30

    Directory of Open Access Journals (Sweden)

    Andreas eVoss

    2015-03-01

    Full Text Available Diffusion models can be used to infer cognitive processes involved in fast binary decision tasks. The model assumes that information is accumulated continuously until one of two thresholds is hit. In the analysis, response time distributions from numerous trials of the decision task are used to estimate a set of parameters mapping distinct cognitive processes. In recent years, diffusion model analyses have become more and more popular in different fields of psychology. This increased popularity is based on the recent development of several software solutions for the parameter estimation. Although these programs make the application of the model relatively easy, there is a shortage of knowledge about different steps of a state-of-the-art diffusion model study. In this paper, we give a concise tutorial on diffusion modelling, and we present fast-dm-30, a thoroughly revised and extended version of the fast-dm software (Voss & Voss, 2007 for diffusion model data analysis. The most important improvement of the fast-dm version is the possibility to choose between different optimization criteria (i.e., Maximum Likelihood, Chi-Square, and Kolmogorov-Smirnov, which differ in applicability for different data sets.

  13. Fast Pyrolysis Process Development Unit for Validating Bench Scale Data

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Robert C. [Iowa State Univ., Ames, IA (United States). Biorenewables Research Lab.. Center for Sustainable Environmental Technologies. Bioeconomy Inst.; Jones, Samuel T. [Iowa State Univ., Ames, IA (United States). Biorenewables Research Lab.. Center for Sustainable Environmental Technologies. Bioeconomy Inst.

    2010-03-31

    The purpose of this project was to prepare and operate a fast pyrolysis process development unit (PDU) that can validate experimental data generated at the bench scale. In order to do this, a biomass preparation system, a modular fast pyrolysis fluidized bed reactor, modular gas clean-up systems, and modular bio-oil recovery systems were designed and constructed. Instrumentation for centralized data collection and process control were integrated. The bio-oil analysis laboratory was upgraded with the addition of analytical equipment needed to measure C, H, O, N, S, P, K, and Cl. To provide a consistent material for processing through the fluidized bed fast pyrolysis reactor, the existing biomass preparation capabilities of the ISU facility needed to be upgraded. A stationary grinder was installed to reduce biomass from bale form to 5-10 cm lengths. A 25 kg/hr rotary kiln drier was installed. It has the ability to lower moisture content to the desired level of less than 20% wt. An existing forage chopper was upgraded with new screens. It is used to reduce biomass to the desired particle size of 2-25 mm fiber length. To complete the material handling between these pieces of equipment, a bucket elevator and two belt conveyors must be installed. The bucket elevator has been installed. The conveyors are being procured using other funding sources. Fast pyrolysis bio-oil, char and non-condensable gases were produced from an 8 kg/hr fluidized bed reactor. The bio-oil was collected in a fractionating bio-oil collection system that produced multiple fractions of bio-oil. This bio-oil was fractionated through two separate, but equally important, mechanisms within the collection system. The aerosols and vapors were selectively collected by utilizing laminar flow conditions to prevent aerosol collection and electrostatic precipitators to collect the aerosols. The vapors were successfully collected through a selective condensation process. The combination of these two mechanisms

  14. A Novel Fast Method for Point-sampled Model Simplification

    Directory of Open Access Journals (Sweden)

    Cao Zhi

    2016-01-01

    Full Text Available A novel fast simplification method for point-sampled statue model is proposed. Simplifying method for 3d model reconstruction is a hot topic in the field of 3D surface construction. But it is difficult as point cloud of many 3d models is very large, so its running time becomes very long. In this paper, a two-stage simplifying method is proposed. Firstly, a feature-preserved non-uniform simplification method for cloud points is presented, which simplifies the data set to remove the redundancy while keeping down the features of the model. Secondly, an affinity clustering simplifying method is used to classify the point cloud into a sharp point or a simple point. The advantage of Affinity Propagation clustering is passing messages among data points and fast speed of processing. Together with the re-sampling, it can dramatically reduce the duration of the process while keep a lower memory cost. Both theoretical analysis and experimental results show that after the simplification, the performance of the proposed method is efficient as well as the details of the surface are preserved well.

  15. PYTRANSIT: fast and easy exoplanet transit modelling in PYTHON

    Science.gov (United States)

    Parviainen, Hannu

    2015-07-01

    We present a fast and user friendly exoplanet transit light-curve modelling package PYTRANSIT, implementing optimized versions of the Giménez and Mandel & Agol transit models. The package offers an object-oriented PYTHON interface to access the two models implemented natively in FORTRAN with OpenMP parallelization. A partial OpenCL version of the quadratic Mandel-Agol model is also included for GPU-accelerated computations. The aim of PYTRANSIT is to facilitate the analysis of photometric time series of exoplanet transits consisting of hundreds of thousands of data points, and of multipassband transit light curves from spectrophotometric observations, as a part of a researcher's programming toolkit for building complex, problem-specific analyses.

  16. Fast Visual Modeling for Plant Based on Real Images

    Institute of Scientific and Technical Information of China (English)

    LI Yun-feng; ZHU Qing-sheng; CAO Yu-kun; LIU Yin-bin; HE Xi-ping

    2004-01-01

    Structures of natural plants are complex and difficult to model. This paper proposes a fast visual modeling for plants based on a small set of images, and establishes a reasonable plant model.Based on knowledge about growth patterns of the plant, image segmentation and 3D reconstruction are first performed to construct the plant skeleton (trunk and major branches), from which the remainder of the plant grows. Then the system produces the realistic plant model images based on image synthesis and validation. It is unnecessary to acquire the complex structure (such as the complex production rules of L-systems). The method provides a high degree of control over the final shape by image validation,resulting in realistic reconstruction.

  17. H∞ Optimal Model Reduction for Singular Fast Subsystems

    Institute of Scientific and Technical Information of China (English)

    WANGJing; ZHANGQing-Ling; LIUWan-Quan; ZHOUYue

    2005-01-01

    In this paper, H∞ optimal model reduction for singular fast subsystems will be investigated. First, error system is established to measure the error magnitude between the original and reduced systems, and it is demonstrated that the new feature for model reduction of singular systems is to make H∞ norm of the error system finite and minimal. The necessary and sufficient condition is derived for the existence of the H∞ suboptimal model reduction problem. Next, we give an exactand practicable algorithm to get the parameters of the reduced subsystems by applying the matrix theory. Meanwhile, the reduced system may be also impulsive. The advantages of the proposed algorithm are that it is more flexible in a straight-forward way without much extra computation, and the order of the reduced systems is as minimal as possible. Finally, one illustrative example is given to illustrate the effectiveness of the proposed model reduction approach.

  18. Modeling of Dynamic Fluid Forces in Fast Switching Valves

    DEFF Research Database (Denmark)

    Roemer, Daniel Beck; Johansen, Per; Pedersen, Henrik Clemmensen

    2015-01-01

    Switching valves experience opposing fluid forces due to movement of the moving member itself, as the surrounding fluid volume must move to accommodate the movement. This movement-induced fluid force may be divided into three main components; the added mass term, the viscous term and the socalled...... is given using an analytically solvable example, showing the explicit form of the force terms and highlighting the significance of the added mass and history term in certain fast switching valve applications. A general approximate model for arbitrary valve geometries is then proposed with offset...

  19. Model Predictive Control-Based Fast Charging for Vehicular Batteries

    Directory of Open Access Journals (Sweden)

    Zhibin Song

    2011-08-01

    Full Text Available Battery fast charging is one of the most significant and difficult techniques affecting the commercialization of electric vehicles (EVs. In this paper, we propose a fast charge framework based on model predictive control, with the aim of simultaneously reducing the charge duration, which represents the out-of-service time of vehicles, and the increase in temperature, which represents safety and energy efficiency during the charge process. The RC model is employed to predict the future State of Charge (SOC. A single mode lumped-parameter thermal model and a neural network trained by real experimental data are also applied to predict the future temperature in simulations and experiments respectively. A genetic algorithm is then applied to find the best charge sequence under a specified fitness function, which consists of two objectives: minimizing the charging duration and minimizing the increase in temperature. Both simulation and experiment demonstrate that the Pareto front of the proposed method dominates that of the most popular constant current constant voltage (CCCV charge method.

  20. Development of a fast-response multi-hole probe for unsteady and turbulent flowfields

    Science.gov (United States)

    Johansen, Espen Sten

    The development of a fast-response aerodynamic probe calibration routine has been completed. This work includes the development of a theoretical probe and application and adaptation of potential flow theory to a fast-response 5-hole probe. Based on the theoretical probe, a procedure to determine the flow angles in flowfields with significant inertial effects was devised. It was further shown that this definition can be used to accurately predict the angles in flowfields with very high frequency oscillations (large inertial effects) over a wide range of flow incidence angles. The velocity magnitude was solved from the governing equation. This equation is a first-order, non-linear, ordinary differential equation, and a predictor-corrector method was formulated to calculate the velocity based on the measured port pressures. An experimental procedure to determine the steady and unsteady pressure coefficients was presented. The steady pressure coefficient is readily calculated from steady calibration data, but the determination of the unsteady coefficient requires a selective averaging procedure based on the rate-of-change parameter. A spherical probe with a fast-response pressure transducer was designed. The spherical probe was oscillated in water flow, and the coefficient determination procedure was experimentally verified. A facility was designed for the unsteady calibration of fast-response probes in air. This facility generates a repeatable velocity oscillation that is sinusoidal in nature with mean velocity up to Mach 0.5 and frequency up to 1.5 kHz. A fast-response 5-hole probe was developed that can resolve frequency content up to 20 kHz, and was used to verify the unsteady calibration routine. Several test cases were presented and excellent prediction capabilities were demonstrated. Acoustic pressure attenuation in the tubing systems for miniature multi-hole probes is discussed, and theoretical models are presented that determine the transfer function of such

  1. Impact of Fast Ignition on Laser Fusion Energy Development

    Science.gov (United States)

    Mirna, Kunioki

    2016-10-01

    Reviewed are the early history of Japanese laser fusion research and the recent achievement of fast ignition research at Institute of Laser Engineering (ILE), Osaka University. After the achievement of high density compression at Osaka University, LLE of University Rochester, and LLNL, the critical issue of Inertial Fusion Energy (IFE) research became the formation of hot spark in a compressed plasma. In this lecture, the history of the fast ignition research will be reviewed and future prospects are presented.

  2. Development of buffers for fast semidry transfer of proteins.

    Science.gov (United States)

    Garić, Dušan; Humbert, Laure; Fils-Aimé, Nadège; Korah, Juliana; Zarfabian, Yasaman; Lebrun, Jean-Jacques; Ali, Suhad

    2013-10-15

    Western blot is an extensively used method for protein detection in cell biology. To optimize this procedure, here we examined a panel of buffers for their ability to efficiently transfer proteins from SDS-polyacrylamide gels onto nitrocellulose membranes in a short 12-min period, designated here as fast semidry transfer. Our results show for the first time that HEPES- and HEPPS/EPPS-based buffers represent the most efficient buffers for fast semidry transfer.

  3. Validation of a FAST Model of the Statoil-Hywind Demo Floating Wind Turbine

    Energy Technology Data Exchange (ETDEWEB)

    Driscoll, Frederick; Jonkman, Jason; Robertson, Amy; Sirnivas, Senu; Skaare, Bjorn; Nielsen, Finn Gunnar

    2016-09-01

    To assess the accuracy of the National Renewable Energy Laboratory's (NREL's) FAST simulation tool for modeling the coupled response of floating offshore wind turbines under realistic open-ocean conditions, NREL developed a FAST model of the Statoil Hywind Demo floating offshore wind turbine, and validated simulation results against field measurements. Field data were provided by Statoil, which conducted a comprehensive test measurement campaign of its demonstration system, a 2.3-MW Siemens turbine mounted on a spar substructure deployed about 10 km off the island of Karmoy in Norway. A top-down approach was used to develop the FAST model, starting with modeling the blades and working down to the mooring system. Design data provided by Siemens and Statoil were used to specify the structural, aerodynamic, and dynamic properties. Measured wind speeds and wave spectra were used to develop the wind and wave conditions used in the model. The overall system performance and behavior were validated for eight sets of field measurements that span a wide range of operating conditions. The simulated controller response accurately reproduced the measured blade pitch and power. The structural and blade loads and spectra of platform motion agree well with the measured data.

  4. Fast and stable numerical method for neuronal modelling

    Science.gov (United States)

    Hashemi, Soheil; Abdolali, Ali

    2016-11-01

    Excitable cell modelling is of a prime interest in predicting and targeting neural activity. Two main limits in solving related equations are speed and stability of numerical method. Since there is a tradeoff between accuracy and speed, most previously presented methods for solving partial differential equations (PDE) are focused on one side. More speed means more accurate simulations and therefore better device designing. By considering the variables in finite differenced equation in proper time and calculating the unknowns in the specific sequence, a fast, stable and accurate method is introduced in this paper for solving neural partial differential equations. Propagation of action potential in giant axon is studied by proposed method and traditional methods. Speed, consistency and stability of the methods are compared and discussed. The proposed method is as fast as forward methods and as stable as backward methods. Forward methods are known as fastest methods and backward methods are stable in any circumstances. Complex structures can be simulated by proposed method due to speed and stability of the method.

  5. Formulation development and evaluation of fast dissolving film of telmisartan

    Directory of Open Access Journals (Sweden)

    Vaishali Y Londhe

    2012-01-01

    Full Text Available Hypertension is a major cause of concern not just in the elderly but also in the youngsters. An effort was made to formulate a fast dissolving film containing telmisartan which is used in the treatment of hypertension with a view to improve the onset of action, therapeutic efficacy, patient compliance and convenience. The major challenge in formulation of oral films of telmisatran is that it shows very less solubility in the pH range of 3-9. Various film forming agents and polyhydric alcohols were evaluated for optimizing composition of fast dissolving films. Fast dissolving films using hydroxypropyl methylcellulose, polyvinyl alcohol, glycerol, sorbitol, menthol and an alkalizer were formulated using solvent casting method. Optimized formulations were evaluated for their weight, thickness, folding endurance, appearance, tensile strength, disintegration time and dissolution profile.

  6. Design Novel 3D Nano Architectures for Developing Ultra Fast Thermal Energy Storage Materials

    Science.gov (United States)

    2015-04-30

    AFRL-AFOSR-UK-TR-2015-0036 Design novel 3D nano-architectures for developing ultra fast thermal energy storage materials...ultra fast thermal energy storage materials 5a. CONTRACT NUMBER 5b. GRANT NUMBER FA8655-12-1-2014 5c. PROGRAM ELEMENT NUMBER 61102F 6. AUTHOR(S...ANSI Std. Z39.18 FINAL TECHNICAL REPORT Project Title : Design novel 3D nano-architectures for developing ultra fast thermal energy storage

  7. A MODEL BASED ALGORITHM FOR FAST DPIV COMPUTING

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Traditional DPIV (Digital Particle Image Velocimetry) methods aremostly based on area-correlation (Willert,C.E.,1991).Though proven to be very time-consuming and very much error prone,they are widely adopted because of they are conceptually simple and easily implemented,and also because there are few alternatives.This paper proposes a non-correlation,conceptually new,fast and efficient approach for DPIV,which takes the nature of flow into consideration.An Incompressible Affined Flow Model (IAFM) is introduced to describe a flow that incorporates rational restraints into the computation.This IAFM,combined with a modified optical flow method-named Total Optical Flow Computation (TOFC),provides a linear system solution to DPIV.Experimental results on real images showed our method to be a very promising approach for DPIV.

  8. Model Versions and Fast Algorithms for Network Epidemiology

    Institute of Scientific and Technical Information of China (English)

    Petter Holme

    2014-01-01

    Network epidemiology has become a core framework for investigating the role of human contact patterns in the spreading of infectious diseases. In network epidemiology, one represents the contact structure as a network of nodes (individuals) connected by links (sometimes as a temporal network where the links are not continuously active) and the disease as a compartmental model (where individuals are assigned states with respect to the disease and follow certain transition rules between the states). In this paper, we discuss fast algorithms for such simulations and also compare two commonly used versions,one where there is a constant recovery rate (the number of individuals that stop being infectious per time is proportional to the number of such people);the other where the duration of the disease is constant. The results show that, for most practical purposes, these versions are qualitatively the same.

  9. Modeling the redshift and energy distributions of fast radio bursts

    Science.gov (United States)

    Cao, Xiao-Feng; Xiao, Ming; Xiao, Fei

    2017-02-01

    Fast radio bursts (FRBs) are one of the most mysterious astronomical phenomena nowadays. The identification of their origin requires more observations in the future and, importantly, deep understandings of the existing observational data. By fitting the redshift and energy distributions of 15 Parkes FRBs, we try to derive their intrinsic energy function and the cosmic evolution of their burst rates. Specifically, while the energy function is assumed as usual to have a single-power-law form, the burst rates are considered to be proportional to the cosmic star formation rates by a redshift-dependent coefficient. Some plausible fittings are obtained, which indicate the power-law assumptions are feasible and effective. The values of the power-law indices could be used to independently constrain candidate FRB models, although parameter degeneracies still exist.

  10. Fast reconstruction of compact context-specific metabolic network models.

    Directory of Open Access Journals (Sweden)

    Nikos Vlassis

    2014-01-01

    Full Text Available Systemic approaches to the study of a biological cell or tissue rely increasingly on the use of context-specific metabolic network models. The reconstruction of such a model from high-throughput data can routinely involve large numbers of tests under different conditions and extensive parameter tuning, which calls for fast algorithms. We present fastcore, a generic algorithm for reconstructing context-specific metabolic network models from global genome-wide metabolic network models such as Recon X. fastcore takes as input a core set of reactions that are known to be active in the context of interest (e.g., cell or tissue, and it searches for a flux consistent subnetwork of the global network that contains all reactions from the core set and a minimal set of additional reactions. Our key observation is that a minimal consistent reconstruction can be defined via a set of sparse modes of the global network, and fastcore iteratively computes such a set via a series of linear programs. Experiments on liver data demonstrate speedups of several orders of magnitude, and significantly more compact reconstructions, over a rival method. Given its simplicity and its excellent performance, fastcore can form the backbone of many future metabolic network reconstruction algorithms.

  11. ORIGINAL ARTICLES FAST scanning in the developing world ...

    African Journals Online (AJOL)

    a priority in trauma management.2 Diagnostic peritoneal lavage (DPL) and .... determining the extent of intra-abdominal injury such as DPL and CT scanning. ... FAST in the treatment algorithm for blunt trauma did not have a significant effect ...

  12. Fast Multiscale Reservoir Simulations using POD-DEIM Model Reduction

    KAUST Repository

    Ghasemi, Mohammadreza

    2015-02-23

    In this paper, we present a global-local model reduction for fast multiscale reservoir simulations in highly heterogeneous porous media with applications to optimization and history matching. Our proposed approach identifies a low dimensional structure of the solution space. We introduce an auxiliary variable (the velocity field) in our model reduction that allows achieving a high degree of model reduction. The latter is due to the fact that the velocity field is conservative for any low-order reduced model in our framework. Because a typical global model reduction based on POD is a Galerkin finite element method, and thus it can not guarantee local mass conservation. This can be observed in numerical simulations that use finite volume based approaches. Discrete Empirical Interpolation Method (DEIM) is used to approximate the nonlinear functions of fine-grid functions in Newton iterations. This approach allows achieving the computational cost that is independent of the fine grid dimension. POD snapshots are inexpensively computed using local model reduction techniques based on Generalized Multiscale Finite Element Method (GMsFEM) which provides (1) a hierarchical approximation of snapshot vectors (2) adaptive computations by using coarse grids (3) inexpensive global POD operations in a small dimensional spaces on a coarse grid. By balancing the errors of the global and local reduced-order models, our new methodology can provide an error bound in simulations. Our numerical results, utilizing a two-phase immiscible flow, show a substantial speed-up and we compare our results to the standard POD-DEIM in finite volume setup.

  13. On modelling the Fast Radio Burst (FRB) population and event rate predictions

    CERN Document Server

    Bera, Apurba; Bharadwaj, Somnath; Bhat, N D Ramesh; Chengalur, Jayaram N

    2016-01-01

    Assuming that Fast Radio Bursts (FRBs) are of extragalactic origin, we have developed a formalism to predict the FRB detection rate and the redshift distribution of the detected events for a telescope with given parameters. We have adopted FRB 110220, for which the emitted pulse energy is estimated to be $E_0 = 5.4 \\times 10^{33}J$, as the reference event. The formalism requires us to assume models for (1) pulse broadening due to scattering in the ionized inter-galactic medium - we consider two different models for this, (2) the frequency spectrum of the emitted pulse - we consider a power law model $E_{\

  14. Are Live Ultrasound Models Replaceable? Traditional vs. Simulated Education Module for FAST

    Directory of Open Access Journals (Sweden)

    Suzanne Bentley

    2015-10-01

    Full Text Available Introduction: The focused assessment with sonography for trauma (FAST is a commonly used and life-saving tool in the initial assessment of trauma patients. The recommended emergency medicine (EM curriculum includes ultrasound and studies show the additional utility of ultrasound training for medical students. EM clerkships vary and often do not contain formal ultrasound instruction. Time constraints for facilitating lectures and hands-on learning of ultrasound are challenging. Limitations on didactics call for development and inclusion of novel educational strategies, such as simulation. The objective of this study was to compare the test, survey, and performance of ultrasound between medical students trained on an ultrasound simulator versus those trained via traditional, hands-on patient format. Methods: This was a prospective, blinded, controlled educational study focused on EM clerkship medical students. After all received a standardized lecture with pictorial demonstration of image acquisition, students were randomized into two groups: control group receiving traditional training method via practice on a human model and intervention group training via practice on an ultrasound simulator. Participants were tested and surveyed on indications and interpretation of FAST and training and confidence with image interpretation and acquisition before and after this educational activity. Evaluation of FAST skills was performed on a human model to emulate patient care and practical skills were scored via objective structured clinical examination (OSCE with critical action checklist. Results: There was no significant difference between control group (N=54 and intervention group (N=39 on pretest scores, prior ultrasound training/education, or ultrasound comfort level in general or on FAST. All students (N=93 showed significant improvement from pre- to post-test scores and significant improvement in comfort level using ultrasound in general and on FAST

  15. Modeling fast and slow gamma oscillations with interneurons of different subtype.

    Science.gov (United States)

    Keeley, Stephen; Fenton, André A; Rinzel, John

    2017-03-01

    Experimental and theoretical studies demonstrate that neuronal gamma oscillations crucially depend on interneurons, but current models do not consider the diversity of known interneuron subtypes. Moreover, in CA1 of the hippocampus, experimental evidence indicates the presence of multiple gamma oscillators, two of which may be coordinated by differing interneuron populations. In this article, we show that models of networks with competing interneuron populations with different postsynaptic effects are sufficient to generate, within CA1, distinct oscillatory regimes. We find that strong mutual inhibition between the interneuron populations permits distinct fast and slow gamma states, whereas weak mutual inhibition generates mixed gamma states. We develop idealized firing rate models to illuminate dynamic properties of these competitive gamma networks, and reinforce these concepts with basic spiking models. The models make several explicit predictions about gamma oscillators in CA1. Specifically, interneurons of different subtype phase-lock to different gamma states, and one population of interneurons is silenced and the other active during fast and slow gamma events. Finally, mutual inhibition between interneuron populations is necessary to generate distinct gamma states. Previous experimental studies indicate that fast and slow gamma oscillations reflect different information processing modes, although it is unclear whether these rhythms are intrinsic or imposed. The models outlined demonstrate that basic architectures can locally generate these oscillations, as well as capture other features of fast and slow gamma, including theta-phase preference and spontaneous transitions between gamma states. These models may extend to describe general dynamics in networks with diverse interneuron populations.NEW & NOTEWORTHY The oscillatory coordination of neural signals is crucial to healthy brain function. We have developed an idealized neuronal model that generates

  16. Self-Organizing Maps for Fast LES Combustion Modeling Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Tremendous advances have been made in the development of large and accurate detailed reaction chemistry models for hydrocarbon fuels. Comparable progress has also...

  17. A Novel Lattice Boltzmann Model For Reactive Flows with Fast Chemistry

    Institute of Scientific and Technical Information of China (English)

    CHEN Sheng; LIU Zhao-Hui; HE Zhu; ZHANG Chao; TIAN Zhi-Wei; SHI Bao-Chang; ZHENG Chu-Guang

    2006-01-01

    @@ A novel lattice Boltzmann model, in which we take the ratio of temperature difference in the temperature field to the environment one to be more than one order of magnitude than before, is developed to simulate two dimensional reactive flows with fast chemistry. Different from the hybrid scheme for reactive flows [Comput.Phys. Commun. 129 (2000)267], this scheme is strictly in a pure lattice Boltzmann style (i.e., we solve the flow, temperature, and concentration fields using the lattice Boltzmann method only). Different from the recent non-coupled lattice Boltzmann scheme [Int. J. Mod. Phys. B 17(2003) 197], the fluid density in our model is coupled directly with the temperature. Excellent agreement between the present results and other numerical data shows that this scheme is an efficient numerical method for practical reactive flows with fast chemistry.

  18. A CFD-based wind solver for a fast response transport and dispersion model

    Energy Technology Data Exchange (ETDEWEB)

    Gowardhan, Akshay A [Los Alamos National Laboratory; Brown, Michael J [Los Alamos National Laboratory; Pardyjak, Eric R [UNIV OF UTAH; Senocak, Inanc [BOISE STATE UNIV

    2010-01-01

    In many cities, ambient air quality is deteriorating leading to concerns about the health of city inhabitants. In urban areas with narrow streets surrounded by clusters of tall buildings, called street canyons, air pollution from traffic emissions and other sources is difficult to disperse and may accumulate resulting in high pollutant concentrations. For various situations, including the evacuation of populated areas in the event of an accidental or deliberate release of chemical, biological and radiological agents, it is important that models should be developed that produce urban flow fields quickly. For these reasons it has become important to predict the flow field in urban street canyons. Various computational techniques have been used to calculate these flow fields, but these techniques are often computationally intensive. Most fast response models currently in use are at a disadvantage in these cases as they are unable to correlate highly heterogeneous urban structures with the diagnostic parameterizations on which they are based. In this paper, a fast and reasonably accurate computational fluid dynamics (CFD) technique that solves the Navier-Stokes equations for complex urban areas has been developed called QUIC-CFD (Q-CFD). This technique represents an intermediate balance between fast (on the order of minutes for a several block problem) and reasonably accurate solutions. The paper details the solution procedure and validates this model for various simple and complex urban geometries.

  19. Fast Virtual Stenting with Active Contour Models in Intracranical Aneurysm.

    Science.gov (United States)

    Zhong, Jingru; Long, Yunling; Yan, Huagang; Meng, Qianqian; Zhao, Jing; Zhang, Ying; Yang, Xinjian; Li, Haiyun

    2016-02-15

    Intracranial stents are becoming increasingly a useful option in the treatment of intracranial aneurysms (IAs). Image simulation of the releasing stent configuration together with computational fluid dynamics (CFD) simulation prior to intervention will help surgeons optimize intervention scheme. This paper proposed a fast virtual stenting of IAs based on active contour model (ACM) which was able to virtually release stents within any patient-specific shaped vessel and aneurysm models built on real medical image data. In this method, an initial stent mesh was generated along the centerline of the parent artery without the need for registration between the stent contour and the vessel. Additionally, the diameter of the initial stent volumetric mesh was set to the maximum inscribed sphere diameter of the parent artery to improve the stenting accuracy and save computational cost. At last, a novel criterion for terminating virtual stent expanding that was based on the collision detection of the axis aligned bounding boxes was applied, making the stent expansion free of edge effect. The experiment results of the virtual stenting and the corresponding CFD simulations exhibited the efficacy and accuracy of the ACM based method, which are valuable to intervention scheme selection and therapy plan confirmation.

  20. FAST: A Fuel And Sheath Modeling Tool for CANDU Reactor Fuel

    Science.gov (United States)

    Prudil, Andrew Albert

    Understanding the behaviour of nuclear fuel during irradiation is a complicated multiphysics problem involving neutronics, chemistry, radiation physics, material-science, solid mechanics, heat transfer and thermal-hydraulics. Due to the complexity and interdependence of the physics and models involved, fuel modeling is typically clone with numerical models. Advancements in both computer hardware and software have made possible new more complex and sophisticated fuel modeling codes. The Fuel And Sheath modelling Tool (FAST) is a fuel performance code that has been developed for modeling nuclear fuel behaviour under normal and transient conditions. The FAST code includes models for heat generation and transport, thermal expansion, elastic strain, densification, fission product swelling, pellet relocation, contact, grain growth, fission gas release, gas and coolant pressure and sheath creep. These models are coupled and solved numerically using the Comsol Multiphysics finite-element platform. The model utilizes a radialaxial geometry of a fuel pellet (including dishing and chamfering) and accompanying fuel sheath allowing the model to predict circumferential ridging. This model has evolved from previous treatments developed at the Royal Military College. The model has now been significantly advanced to include: a more detailed pellet geometry, localized pellet-to-sheath gap size and contact pressure, ability to model cracked pellets, localized fuel burnup for material property models, improved U02 densification behaviour, fully 2-dimensional model for the sheath, additional creep models, additional material models, an FEM Booth-diffusion model for fission gas release (including ability to model temperature and power changes), a capability for end-of-life predictions, the ability to utilize text files as model inputs, and provides a first time integration of normal operating conditions (NOC) and transient fuel models into a single code (which has never been achieved

  1. Large-signal PIN diode model for ultra-fast photodetectors

    DEFF Research Database (Denmark)

    Krozer, Viktor; Fritsche, C

    2005-01-01

    A large-signal model for PIN photodetector is presented, which can be applied to ultra-fast photodetection and THz signal generation. The model takes into account the tunnelling and avalanche breakdown, which is important for avalanche photodiodes. The model is applied to ultra-fast superlattice...

  2. Fast Prediction and Evaluation of Gravitational Waveforms Using Surrogate Models

    Directory of Open Access Journals (Sweden)

    Scott E. Field

    2014-07-01

    Full Text Available We propose a solution to the problem of quickly and accurately predicting gravitational waveforms within any given physical model. The method is relevant for both real-time applications and more traditional scenarios where the generation of waveforms using standard methods can be prohibitively expensive. Our approach is based on three offline steps resulting in an accurate reduced order model in both parameter and physical dimensions that can be used as a surrogate for the true or fiducial waveform family. First, a set of m parameter values is determined using a greedy algorithm from which a reduced basis representation is constructed. Second, these m parameters induce the selection of m time values for interpolating a waveform time series using an empirical interpolant that is built for the fiducial waveform family. Third, a fit in the parameter dimension is performed for the waveform’s value at each of these m times. The cost of predicting L waveform time samples for a generic parameter choice is of order O(mL+mc_{fit} online operations, where c_{fit} denotes the fitting function operation count and, typically, m≪L. The result is a compact, computationally efficient, and accurate surrogate model that retains the original physics of the fiducial waveform family while also being fast to evaluate. We generate accurate surrogate models for effective-one-body waveforms of nonspinning binary black hole coalescences with durations as long as 10^{5}M, mass ratios from 1 to 10, and for multiple spherical harmonic modes. We find that these surrogates are more than 3 orders of magnitude faster to evaluate as compared to the cost of generating effective-one-body waveforms in standard ways. Surrogate model building for other waveform families and models follows the same steps and has the same low computational online scaling cost. For expensive numerical simulations of binary black hole coalescences, we thus anticipate extremely large speedups in

  3. Composite model of microstructural evolution in austenitic stainless steel under fast neutron irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Stoller, R.E.; Odette, G.R.

    1986-01-01

    A rate-theory-based model has been developed which includes the simultaneous evolution of the dislocation and cavity components of the microstructure of irradiated austenitic stainless steels. Previous work has generally focused on developing models for void swelling while neglecting the time dependence of the dislocation structure. These models have broadened our understanding of the physical processes that give rise to swelling, e.g., the role of helium and void formation from critically-sized bubbles. That work has also demonstrated some predictive capability by successful calibration to fit the results of fast reactor swelling data. However, considerable uncertainty about the values of key parameters in these models limits their usefulness as predictive tools. Hence the use of such models to extrapolate fission reactor swelling data to fusion reactor conditions is compromised.

  4. Development and Benchmarking of a Hybrid PIC Code For Dense Plasmas and Fast Ignition

    Energy Technology Data Exchange (ETDEWEB)

    Witherspoon, F. Douglas [HyperV Technologies Corp.; Welch, Dale R. [Voss Scientific, LLC; Thompson, John R. [FAR-TECH, Inc.; MacFarlane, Joeseph J. [Prism Computational Sciences Inc.; Phillips, Michael W. [Advanced Energy Systems, Inc.; Bruner, Nicki [Voss Scientific, LLC; Mostrom, Chris [Voss Scientific, LLC; Thoma, Carsten [Voss Scientific, LLC; Clark, R. E. [Voss Scientific, LLC; Bogatu, Nick [FAR-TECH, Inc.; Kim, Jin-Soo [FAR-TECH, Inc.; Galkin, Sergei [FAR-TECH, Inc.; Golovkin, Igor E. [Prism Computational Sciences, Inc.; Woodruff, P. R. [Prism Computational Sciences, Inc.; Wu, Linchun [HyperV Technologies Corp.; Messer, Sarah J. [HyperV Technologies Corp.

    2014-05-20

    Radiation processes play an important role in the study of both fast ignition and other inertial confinement schemes, such as plasma jet driven magneto-inertial fusion, both in their effect on energy balance, and in generating diagnostic signals. In the latter case, warm and hot dense matter may be produced by the convergence of a plasma shell formed by the merging of an assembly of high Mach number plasma jets. This innovative approach has the potential advantage of creating matter of high energy densities in voluminous amount compared with high power lasers or particle beams. An important application of this technology is as a plasma liner for the flux compression of magnetized plasma to create ultra-high magnetic fields and burning plasmas. HyperV Technologies Corp. has been developing plasma jet accelerator technology in both coaxial and linear railgun geometries to produce plasma jets of sufficient mass, density, and velocity to create such imploding plasma liners. An enabling tool for the development of this technology is the ability to model the plasma dynamics, not only in the accelerators themselves, but also in the resulting magnetized target plasma and within the merging/interacting plasma jets during transport to the target. Welch pioneered numerical modeling of such plasmas (including for fast ignition) using the LSP simulation code. Lsp is an electromagnetic, parallelized, plasma simulation code under development since 1995. It has a number of innovative features making it uniquely suitable for modeling high energy density plasmas including a hybrid fluid model for electrons that allows electrons in dense plasmas to be modeled with a kinetic or fluid treatment as appropriate. In addition to in-house use at Voss Scientific, several groups carrying out research in Fast Ignition (LLNL, SNL, UCSD, AWE (UK), and Imperial College (UK)) also use LSP. A collaborative team consisting of HyperV Technologies Corp., Voss Scientific LLC, FAR-TECH, Inc., Prism

  5. Fuel development for gas-cooled fast reactors

    Science.gov (United States)

    Meyer, M. K.; Fielding, R.; Gan, J.

    2007-09-01

    The Generation IV Gas-cooled Fast Reactor (GFR) concept is proposed to combine the advantages of high-temperature gas-cooled reactors (such as efficient direct conversion with a gas turbine and the potential for application of high-temperature process heat), with the sustainability advantages that are possible with a fast-spectrum reactor. The latter include the ability to fission all transuranics and the potential for breeding. The GFR is part of a consistent set of gas-cooled reactors that includes a medium-term Pebble Bed Modular Reactor (PBMR)-like concept, or concepts based on the Gas Turbine Modular Helium Reactor (GT-MHR), and specialized concepts such as the Very High-Temperature Reactor (VHTR), as well as actinide burning concepts [A Technology Roadmap for Generation IV Nuclear Energy Systems, US DOE Nuclear Energy Research Advisory Committee and the Generation IV International Forum, December 2002]. To achieve the necessary high power density and the ability to retain fission gas at high temperature, the primary fuel concept proposed for testing in the United States is dispersion coated fuel particles in a ceramic matrix. Alternative fuel concepts considered in the US and internationally include coated particle beds, ceramic clad fuel pins, and novel ceramic 'honeycomb' structures. Both mixed carbide and mixed nitride-based solid solutions are considered as fuel phases.

  6. Realistic Modeling of Fast MHD Wave Trains in Coronal Active Regions

    Science.gov (United States)

    Ofman, Leon; Sun, Xudong

    2017-08-01

    Motivated by recent SDO/AIA observations we have developed realistic modeling of quasi-periodic, fast-mode propagating MHD wave trains (QFPs) using 3D MHD model initiated with potential magnetic field extrapolated from the solar coronal boundary. Localized quasi-periodic pulsations associated with C-class flares that drive the waves (as deduced from observations) are modeled with transverse periodic displacement of magnetic field at the lower coronal boundary. The modeled propagating speed and the form of the wave expansions matches the observed fast MHD waves speed >1000 km/s and topology. We study the parametric dependence of the amplitude, propagation, and damping of the waves for a range of key model parameters, such as the background temperature, density, and the location of the flaring site within the active region. We investigate the interaction of multiple QFP wave trains excited by adjacent flaring sources. We use the model results to synthesize EUV intensities in multiple AIA channels and obtain the model parameters that best reproduce the properties of observed QFPs, such as the recent DEM analysis. We discuss the implications of our modeling results for the seismological application of QFPs for the diagnostic of the active region field, flare pulsations, end estimate the energy flux carried by the waves.

  7. The fast development of solar terrestrial sciences in Taiwan

    Science.gov (United States)

    Liu, Jann-Yenq; Chang, Loren Chee-Wei; Chao, Chi-Kuang; Chen, Ming-Quey; Chu, Yen-Hsyang; Hau, Lin-Ni; Huang, Chien-Ming; Kuo, Cheng-Ling; Lee, Lou-Chuang; Lyu, Ling-Hsiao; Lin, Chia-Hsien; Pan, Chen-Jeih; Shue, Jih-Hong; Su, Ching-Lun; Tsai, Lung-Chih; Yang, Ya-Hui; Lin, Chien-Hung; Hsu, Rue-Ron; Su, Han-Tzong

    2016-12-01

    In Taiwan, research and education of solar terrestrial sciences began with a ground-based ionosonde operated by Ministry of Communications in 1952 and courses of ionospheric physics and space physics offered by National Central University (NCU) in 1959, respectively. Since 1990, to enhance both research and education, the Institute of Space Science at NCU has been setting up and operating ground-based observations of micropulsations, very high-frequency radar, low-latitude ionospheric tomography network, high-frequency Doppler sounder, digital ionosondes, and total electron content (TEC) derived from ground-based GPS receivers to study the morphology of the ionosphere for diurnal, seasonal, geophysical, and solar activity variations, as well as the ionosphere response to solar flares, solar wind, solar eclipses, magnetic storms, earthquakes, tsunami, and so on. Meanwhile, to have better understanding on physics and mechanisms, model simulations for the heliosphere, solar wind, magnetosphere, and ionosphere are also introduced and developed. After the 21 September 1999 Mw7.6 Chi-Chi earthquake, seismo-ionospheric precursors and seismo-traveling ionospheric disturbances induced by earthquakes become the most interesting and challenging research topics of the world. The development of solar terrestrial sciences grows even much faster after National Space Origination has been launching a series of FORMOSAT satellites since 1999. ROCSAT-1 (now renamed FORMOSAT-1) measures the ion composition, density, temperature, and drift velocity at the 600-km altitude in the low-latitude ionosphere; FORMOSAT-2 is to investigate lightning-induced transient luminous events, polar aurora, and upper atmospheric airglow, and FORMOSAT-3 probes ionospheric electron density profiles of the globe. In the near future, FORMOSAT-5 and FORMOSAT-7/COSMIC-2 will be employed for studying solar terrestrial sciences. These satellite missions play an important role on the recent development of solar

  8. A Network Traffic Generator Model for Fast Network-on-Chip Simulation

    DEFF Research Database (Denmark)

    Mahadevan, Shankar; Angiolini, Frederico; Storgaard, Michael

    2005-01-01

    For Systems-on-Chip (SoCs) development, a predominant part of the design time is the simulation time. Performance evaluation and design space exploration of such systems in bit- and cycle-true fashion is becoming prohibitive. We propose a traffic generation (TG) model that provides a fast...... and effective Network-on-Chip (NoC) development and debugging environment. By capturing the type and the timestamp of communication events at the boundary of an IP core in a reference environment, the TG can subsequently emulate the core's communication behavior in different environments. Access patterns...

  9. Stochastic Mode-Reduction in Models with Conservative Fast Sub-Systems

    OpenAIRE

    Jain, Ankita; Timofeyev, Ilya; Vanden-Eijnden, Eric

    2014-01-01

    A stochastic mode reduction strategy is applied to multiscale models with a deterministic energy-conserving fast sub-system. Specifically, we consider situations where the slow variables are driven stochastically and interact with the fast sub-system in an energy-conserving fashion. Since the stochastic terms only affect the slow variables, the fast-subsystem evolves deterministically on a sphere of constant energy. However, in the full model the radius of the sphere slowly changes due to the...

  10. Recent developments in fast spectroscopy for plant mineral analysis

    Directory of Open Access Journals (Sweden)

    Marie evan Maarschalkerweerd

    2015-03-01

    Full Text Available Ideal fertilizer management to optimize plant productivity and quality is more relevant than ever, as global food demands increase along with the rapidly growing world population. At the same time, sub-optimal or excessive use of fertilizers leads to severe environmental damage in areas of intensive crop production. The approaches of soil and plant mineral analysis are briefly compared and discussed here, and the new techniques using fast spectroscopy that offer cheap, rapid and easy-to-use analysis of plant nutritional status are reviewed. The majority of these methods use vibrational spectroscopy, such as Visual-Near Infrared (Vis-NIR and to a lesser extent Ultraviolet (UV and Mid-Infrared (MIR spectroscopy. Advantages of and problems with application of these techniques are thoroughly discussed. Spectroscopic techniques considered having major potential for plant mineral analysis, such as chlorophyll a fluorescence, X-ray fluorescence (XRF and Laser-Induced Breakdown Spectroscopy (LIBS are also described.

  11. A Fast All-sky Radiation Model for Solar applications (FARMS): Algorithm and performance evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Xie, Yu; Sengupta, Manajit; Dudhia, Jimy

    2016-10-01

    Radiative transfer (RT) models simulating broadband solar radiation have been widely used by atmospheric scientists to model solar resources for various energy applications such as operational forecasting. Due to the complexity of solving the RT equation, the computation under cloudy conditions can be extremely time-consuming, though many approximations (e.g., two-stream approach and delta-M truncation scheme) have been utilized. Thus, a more efficient RT model is crucial for model developers as a new option for approximating solar radiation at the land surface with minimal loss of accuracy. In this study, we developed a fast all-sky radiation model for solar applications (FARMS) using the simplified clear-sky RT model, REST2, and simulated cloud transmittances and reflectances from the Rapid Radiation Transfer Model (RRTM) with a 16-stream Discrete Ordinates Radiative Transfer (DISORT). Simulated lookup tables (LUTs) of cloud transmittances and reflectances are created by varying cloud optical thicknesses, cloud particle sizes, and solar zenith angles. Equations with optimized parameters are fitted to the cloud transmittances and reflectances to develop the model. The all-sky solar irradiance at the land surface can then be computed rapidly by combining REST2 with the cloud transmittances and reflectances. This new RT model is more than 1,000 times faster than those currently utilized in solar resource assessment and forecasting because it does not explicitly solve the RT equation for each individual cloud condition. Our results indicate that the accuracy of the fast radiative transfer model is comparable to or better than two-stream approximation in term of computing cloud transmittance and solar radiation.

  12. Develop a Model Component

    Science.gov (United States)

    Ensey, Tyler S.

    2013-01-01

    During my internship at NASA, I was a model developer for Ground Support Equipment (GSE). The purpose of a model developer is to develop and unit test model component libraries (fluid, electrical, gas, etc.). The models are designed to simulate software for GSE (Ground Special Power, Crew Access Arm, Cryo, Fire and Leak Detection System, Environmental Control System (ECS), etc. .) before they are implemented into hardware. These models support verifying local control and remote software for End-Item Software Under Test (SUT). The model simulates the physical behavior (function, state, limits and 110) of each end-item and it's dependencies as defined in the Subsystem Interface Table, Software Requirements & Design Specification (SRDS), Ground Integrated Schematic (GIS), and System Mechanical Schematic.(SMS). The software of each specific model component is simulated through MATLAB's Simulink program. The intensiv model development life cycle is a.s follows: Identify source documents; identify model scope; update schedule; preliminary design review; develop model requirements; update model.. scope; update schedule; detailed design review; create/modify library component; implement library components reference; implement subsystem components; develop a test script; run the test script; develop users guide; send model out for peer review; the model is sent out for verifictionlvalidation; if there is empirical data, a validation data package is generated; if there is not empirical data, a verification package is generated; the test results are then reviewed; and finally, the user. requests accreditation, and a statement of accreditation is prepared. Once each component model is reviewed and approved, they are intertwined together into one integrated model. This integrated model is then tested itself, through a test script and autotest, so that it can be concluded that all models work conjointly, for a single purpose. The component I was assigned, specifically, was a

  13. Selective innervation of fast and slow muscle regions during early chick neuromuscular development.

    Science.gov (United States)

    Rafuse, V F; Milner, L D; Landmesser, L T

    1996-11-01

    The electrical properties of adult motoneurons are well matched to the contractile properties of the fast or slow muscle fibers that they innervate. How this precise matching occurs developmentally is not known. To investigate whether motoneurons exhibit selectivity in innervating discrete muscle regions, containing either fast or slow muscle fibers during early neuromuscular development, we caused embryonic chick hindlimb muscles to become innervated by segmentally inappropriate motoneurons. We used the in vitro spinal cord-hindlimb preparation to identify electrophysiologically the pools of foreign motoneurons innervating the posterior iliotibialis (pITIB), an all-fast muscle, and the iliofibularis (IFIB), a partitioned muscle containing discrete fast and slow regions. The results showed that the pITIB and the fast region of the IFIB were exclusively innervated by motoneurons that normally supply fast muscles. In contrast, the slow region of the IFIB was always innervated by motoneuron pools that normally supply slow muscles. Some experimental IFIB muscles lacked a fast region and were innervated solely by "slow" motoneurons. In addition, the intramuscular nerve branching patterns were always appropriate to the fast-slow nature of the muscle (region) innervated. The selective innervation was found early in the motoneuron death period, and we found no evidence that motoneurons grew into appropriate muscle regions, but failed to form functional contacts. Together, these results support the hypothesis that different classes of motoneurons exhibit molecular differences that allow them to project selectively to, and innervate, muscle fibers of the appropriate type during early neuromuscular development.

  14. Homology Modeling a Fast Tool for Drug Discovery: Current Perspectives

    Science.gov (United States)

    Vyas, V. K.; Ukawala, R. D.; Ghate, M.; Chintha, C.

    2012-01-01

    Major goal of structural biology involve formation of protein-ligand complexes; in which the protein molecules act energetically in the course of binding. Therefore, perceptive of protein-ligand interaction will be very important for structure based drug design. Lack of knowledge of 3D structures has hindered efforts to understand the binding specificities of ligands with protein. With increasing in modeling software and the growing number of known protein structures, homology modeling is rapidly becoming the method of choice for obtaining 3D coordinates of proteins. Homology modeling is a representation of the similarity of environmental residues at topologically corresponding positions in the reference proteins. In the absence of experimental data, model building on the basis of a known 3D structure of a homologous protein is at present the only reliable method to obtain the structural information. Knowledge of the 3D structures of proteins provides invaluable insights into the molecular basis of their functions. The recent advances in homology modeling, particularly in detecting and aligning sequences with template structures, distant homologues, modeling of loops and side chains as well as detecting errors in a model contributed to consistent prediction of protein structure, which was not possible even several years ago. This review focused on the features and a role of homology modeling in predicting protein structure and described current developments in this field with victorious applications at the different stages of the drug design and discovery. PMID:23204616

  15. Fast and Stable Signal Deconvolution via Compressible State-Space Models.

    Science.gov (United States)

    Kazemipour, Abbas; Liu, Ji; Solarana, Krystyna; Nagode, Daniel; Kanold, Patrick; Wu, Min; Babadi, Behtash

    2017-04-13

    Common biological measurements are in the form of noisy convolutions of signals of interest with possibly unknown and transient blurring kernels. Examples include EEG and calcium imaging data. Thus, signal deconvolution of these measurements is crucial in understanding the underlying biological processes. The objective of this paper is to develop fast and stable solutions for signal deconvolution from noisy, blurred and undersampled data, where the signals are in the form of discrete events distributed in time and space. We introduce compressible state-space models as a framework to model and estimate such discrete events. These state-space models admit abrupt changes in the states and have a convergent transition matrix, and are coupled with compressive linear measurements. We consider a dynamic compressive sensing optimization problem and develop a fast solution, using two nested Expectation Maximization algorithms, to jointly estimate the states as well as their transition matrices. Under suitable sparsity assumptions on the dynamics, we prove optimal stability guarantees for the recovery of the states and present a method for the identification of the underlying discrete events with precise confidence bounds. We present simulation studies as well as application to calcium deconvolution and sleep spindle detection, which verify our theoretical results and show significant improvement over existing techniques. Our results show that by explicitly modeling the dynamics of the underlying signals, it is possible to construct signal deconvolution solutions that are scalable, statistically robust, and achieve high temporal resolution. Our proposed methodology provides a framework for modeling and deconvolution of noisy, blurred, and undersampled measurements in a fast and stable fashion, with potential application to a wide range of biological data.

  16. 'Bubble chamber model' of fast atom bombardment induced processes.

    Science.gov (United States)

    Kosevich, Marina V; Shelkovsky, Vadim S; Boryak, Oleg A; Orlov, Vadim V

    2003-01-01

    A hypothesis concerning FAB mechanisms, referred to as a 'bubble chamber FAB model', is proposed. This model can provide an answer to the long-standing question as to how fragile biomolecules and weakly bound clusters can survive under high-energy particle impact on liquids. The basis of this model is a simple estimation of saturated vapour pressure over the surface of liquids, which shows that all liquids ever tested by fast atom bombardment (FAB) and liquid secondary ion mass spectrometry (SIMS) were in the superheated state under the experimental conditions applied. The result of the interaction of the energetic particles with superheated liquids is known to be qualitatively different from that with equilibrium liquids. It consists of initiation of local boiling, i.e., in formation of vapour bubbles along the track of the energetic particle. This phenomenon has been extensively studied in the framework of nuclear physics and provides the basis for construction of the well-known bubble chamber detectors. The possibility of occurrence of similar processes under FAB of superheated liquids substantiates a conceptual model of emission of secondary ions suggested by Vestal in 1983, which assumes formation of bubbles beneath the liquid surface, followed by their bursting accompanied by release of microdroplets and clusters as a necessary intermediate step for the creation of molecular ions. The main distinctive feature of the bubble chamber FAB model, proposed here, is that the bubbles are formed not in the space and time-restricted impact-excited zone, but in the nearby liquid as a 'normal' boiling event, which implies that the temperature both within the bubble and in the droplets emerging on its burst is practically the same as that of the bulk liquid sample. This concept can resolve the paradox of survival of intact biomolecules under FAB, since the part of the sample participating in the liquid-gas transition via the bubble mechanism has an ambient temperature

  17. Validation of a FAST Model of the SWAY Prototype Floating Wind Turbine

    Energy Technology Data Exchange (ETDEWEB)

    Koh, J. H. [Nanyang Technological Univ. (Singapore); Ng, E. Y. K. [Nanyang Technological Univ. (Singapore); Robertson, Amy [National Renewable Energy Lab. (NREL), Golden, CO (United States); Jonkman, Jason [National Renewable Energy Lab. (NREL), Golden, CO (United States); Driscoll, Frederick [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-06-01

    As part of a collaboration of the National Renewable Energy Laboratory (NREL) and SWAY AS, NREL installed scientific wind, wave, and motion measurement equipment on the spar-type 1/6.5th-scale prototype SWAY floating offshore wind system. The equipment enhanced SWAY's data collection and allowed SWAY to verify the concept and NREL to validate a FAST model of the SWAY design in an open-water condition. Nanyang Technological University (NTU), in collaboration with NREL, assisted with the validation. This final report gives an overview of the SWAY prototype and NREL and NTU's efforts to validate a model of the system. The report provides a summary of the different software tools used in the study, the modeling strategies, and the development of a FAST model of the SWAY prototype wind turbine, including justification of the modeling assumptions. Because of uncertainty in system parameters and modeling assumptions due to the complexity of the design, several system properties were tuned to better represent the system and improve the accuracy of the simulations. Calibration was performed using data from a static equilibrium test and free-decay tests.

  18. The development of fast tantalum foil targets for short-lived isotopes

    Energy Technology Data Exchange (ETDEWEB)

    Bennett, J.R.J. E-mail: roger.bennett@rl.ac.uk; Bergmann, U.C.; Drumm, P.V.; Ravn, H

    2003-05-01

    The most recent developments of fast tantalum foil targets for short-lived isotopes are described and the performance of the targets at ISOLDE with beams of {sup 11}Li, {sup 12}Be and {sup 14}Be is given.

  19. Development of a Calcium Phosphate Nanocomposite for Fast Fluorogenic Detection of Bacteria

    Directory of Open Access Journals (Sweden)

    Claudio R. Martínez

    2014-09-01

    Full Text Available Current procedures for the detection and identification of bacterial infections are laborious, time-consuming, and require a high workload and well-equipped laboratories. Therefore the work presented herein developed a simple, fast, and low cost method for bacterial detection based on hydroxyapatite nanoparticles with a nutritive mixture and the fluorogenic substrate. Calcium phosphate ceramic nanoparticles were characterized and integrated with a nutritive mixture for the early detection of bacteria by visual as well as fluorescence spectroscopy techniques. The composite was obtained by combining calcium phosphate nanoparticles (Ca:P ratio, 1.33:1 with a nutritive mixture of protein hydrolysates and carbon sources, which promote fast bacterial multiplication, and the fluorogenic substrate 4-methylumbellipheryl-β-d-glucuronide (MUG. The composite had an average particle size of 173.2 nm and did not show antibacterial activity against Gram-negative or Gram-positive bacteria. After an Escherichia coli suspension was in contact with the composite for 60–90 min, fluorescence detected under UV light or by fluorescence spectrophotometer indicated the presence of bacteria. Intense fluorescence was observed after incubation for a maximum of 90 min. Thus, this calcium phosphate nanocomposite system may be useful as a model for the development of other nanoparticle composites for detection of early bacterial adhesion.

  20. An artificial neural network based fast radiative transfer model for simulating infrared sounder radiances

    Indian Academy of Sciences (India)

    Praveen Krishnan; K Srinivasa Ramanujam; C Balaji

    2012-08-01

    The first step in developing any algorithm to retrieve the atmospheric temperature and humidity parameters at various pressure levels is the simulation of the top of the atmosphere radiances that can be measured by the satellite. This study reports the results of radiative transfer simulations for the multichannel infrared sounder of the proposed Indian satellite INSAT-3D due to be launched shortly. Here, the widely used community software k Compressed Atmospheric Radiative Transfer Algorithm (kCARTA) is employed for performing the radiative transfer simulations. Though well established and benchmarked, kCARTA is a line-by-line solver and hence takes enormous computational time and effort for simulating the multispectral radiances for a given atmospheric scene. This necessitates the development of a much faster and at the same time, equally accurate RT model that can drive a real-time retrieval algorithm. In the present study, a fast radiative transfer model using neural networks is proposed to simulate radiances corresponding to the wavenumbers of INSAT-3D. Realistic atmospheric temperature and humidity profiles have been used for training the network. Spectral response functions of GOES-13, a satellite similar in construction, purpose and design and already in use are used. The fast RT model is able to simulate the radiances for 1200 profiles in 18 ms for a 15-channel GOES profile, with a correlation coefficient of over 99%. Finally, the robustness of the model is tested using additional synthetic profiles generated using empirical orthogonal functions (EOF).

  1. In vivo cell tracking of mouse embryonic myoblasts and fast fibers during development.

    Science.gov (United States)

    Guerrero, Lucia; Villar, Pedro; Martínez, Lidia; Badia-Careaga, Claudio; Arredondo, Juan J; Cervera, Margarita

    2014-09-01

    Fast and slow TnI are co-expressed in E11.5 embryos, and fast TnI is present from the very beginning of myogenesis. A novel green fluorescent protein (GFP) reporter mouse lines (FastTnI/GFP lines) that carry the primary and secondary enhancer elements of the mouse fast troponin I (fast TnI), in which reporter expression correlates precisely with distribution of the endogenous fTnI protein was generated. Using the FastTnI/GFP mouse model, we characterized the early myogenic events in mice, analyzing the migration of GFP+ myoblasts, and the formation of primary and secondary myotubes in transgenic embryos. Interestingly, we found that the two contractile fast and slow isoforms of TnI are expressed during the migration of myoblasts from the somites to the limbs and body wall, suggesting that both participate in these events. Since no sarcomeres are present in myoblasts, we speculate that the function of fast TnI in early myogenesis is, like Myosin and Tropomyosin, to participate in cell movement during the initial myogenic stages. genesis © 2014 Wiley Periodicals, Inc.

  2. Development and Benchmarking of a Hybrid PIC Code For Dense Plasmas and Fast Ignition

    Energy Technology Data Exchange (ETDEWEB)

    Witherspoon, F. Douglas [HyperV Technologies Corp.; Welch, Dale R. [Voss Scientific, LLC; Thompson, John R. [FAR-TECH, Inc.; MacFarlane, Joeseph J. [Prism Computational Sciences Inc.; Phillips, Michael W. [Advanced Energy Systems, Inc.; Bruner, Nicki [Voss Scientific, LLC; Mostrom, Chris [Voss Scientific, LLC; Thoma, Carsten [Voss Scientific, LLC; Clark, R. E. [Voss Scientific, LLC; Bogatu, Nick [FAR-TECH, Inc.; Kim, Jin-Soo [FAR-TECH, Inc.; Galkin, Sergei [FAR-TECH, Inc.; Golovkin, Igor E. [Prism Computational Sciences, Inc.; Woodruff, P. R. [Prism Computational Sciences, Inc.; Wu, Linchun [HyperV Technologies Corp.; Messer, Sarah J. [HyperV Technologies Corp.

    2014-05-20

    Radiation processes play an important role in the study of both fast ignition and other inertial confinement schemes, such as plasma jet driven magneto-inertial fusion, both in their effect on energy balance, and in generating diagnostic signals. In the latter case, warm and hot dense matter may be produced by the convergence of a plasma shell formed by the merging of an assembly of high Mach number plasma jets. This innovative approach has the potential advantage of creating matter of high energy densities in voluminous amount compared with high power lasers or particle beams. An important application of this technology is as a plasma liner for the flux compression of magnetized plasma to create ultra-high magnetic fields and burning plasmas. HyperV Technologies Corp. has been developing plasma jet accelerator technology in both coaxial and linear railgun geometries to produce plasma jets of sufficient mass, density, and velocity to create such imploding plasma liners. An enabling tool for the development of this technology is the ability to model the plasma dynamics, not only in the accelerators themselves, but also in the resulting magnetized target plasma and within the merging/interacting plasma jets during transport to the target. Welch pioneered numerical modeling of such plasmas (including for fast ignition) using the LSP simulation code. Lsp is an electromagnetic, parallelized, plasma simulation code under development since 1995. It has a number of innovative features making it uniquely suitable for modeling high energy density plasmas including a hybrid fluid model for electrons that allows electrons in dense plasmas to be modeled with a kinetic or fluid treatment as appropriate. In addition to in-house use at Voss Scientific, several groups carrying out research in Fast Ignition (LLNL, SNL, UCSD, AWE (UK), and Imperial College (UK)) also use LSP. A collaborative team consisting of HyperV Technologies Corp., Voss Scientific LLC, FAR-TECH, Inc., Prism

  3. Modeling of movement-induced and flow-induced fluid forces in fast switching valves

    DEFF Research Database (Denmark)

    Roemer, Daniel Beck; Johansen, Per; Schmidt, Lasse

    2015-01-01

    Fast switching fluid power valves set strict requirements on performance, size and energy efficiency and simulation models are therefore needed to obtain good designs of such components. The valve moving member is subject to fluid forces depending on the valve flow rate and movement of the valve...... valve design. Simulated results of the total fluid force are presented showing the movement-induced fluid force to be significant for a reference application. The model form established is useful for valve designers during development and for accurate operation simulation....... member itself. These fluid forces may be accurately simulated using Computational Fluid Dynamics (CFD) analysis, but such models suffer from being computationally expensive and is not suited for optimization routines. In this paper, a computationally inexpensive method for modeling the fluid forces...

  4. FAST: FAST Analysis of Sequences Toolbox.

    Science.gov (United States)

    Lawrence, Travis J; Kauffman, Kyle T; Amrine, Katherine C H; Carper, Dana L; Lee, Raymond S; Becich, Peter J; Canales, Claudia J; Ardell, David H

    2015-01-01

    FAST (FAST Analysis of Sequences Toolbox) provides simple, powerful open source command-line tools to filter, transform, annotate and analyze biological sequence data. Modeled after the GNU (GNU's Not Unix) Textutils such as grep, cut, and tr, FAST tools such as fasgrep, fascut, and fastr make it easy to rapidly prototype expressive bioinformatic workflows in a compact and generic command vocabulary. Compact combinatorial encoding of data workflows with FAST commands can simplify the documentation and reproducibility of bioinformatic protocols, supporting better transparency in biological data science. Interface self-consistency and conformity with conventions of GNU, Matlab, Perl, BioPerl, R, and GenBank help make FAST easy and rewarding to learn. FAST automates numerical, taxonomic, and text-based sorting, selection and transformation of sequence records and alignment sites based on content, index ranges, descriptive tags, annotated features, and in-line calculated analytics, including composition and codon usage. Automated content- and feature-based extraction of sites and support for molecular population genetic statistics make FAST useful for molecular evolutionary analysis. FAST is portable, easy to install and secure thanks to the relative maturity of its Perl and BioPerl foundations, with stable releases posted to CPAN. Development as well as a publicly accessible Cookbook and Wiki are available on the FAST GitHub repository at https://github.com/tlawrence3/FAST. The default data exchange format in FAST is Multi-FastA (specifically, a restriction of BioPerl FastA format). Sanger and Illumina 1.8+ FastQ formatted files are also supported. FAST makes it easier for non-programmer biologists to interactively investigate and control biological data at the speed of thought.

  5. FAST: FAST Analysis of Sequences Toolbox

    Directory of Open Access Journals (Sweden)

    Travis J. Lawrence

    2015-05-01

    Full Text Available FAST (FAST Analysis of Sequences Toolbox provides simple, powerful open source command-line tools to filter, transform, annotate and analyze biological sequence data. Modeled after the GNU (GNU’s Not Unix Textutils such as grep, cut, and tr, FAST tools such as fasgrep, fascut, and fastr make it easy to rapidly prototype expressive bioinformatic workflows in a compact and generic command vocabulary. Compact combinatorial encoding of data workflows with FAST commands can simplify the documentation and reproducibility of bioinformatic protocols, supporting better transparency in biological data science. Interface self-consistency and conformity with conventions of GNU, Matlab, Perl, BioPerl, R and GenBank help make FAST easy and rewarding to learn. FAST automates numerical, taxonomic, and text-based sorting, selection and transformation of sequence records and alignment sites based on content, index ranges, descriptive tags, annotated features, and in-line calculated analytics, including composition and codon usage. Automated content- and feature-based extraction of sites and support for molecular population genetic statistics makes FAST useful for molecular evolutionary analysis. FAST is portable, easy to install and secure thanks to the relative maturity of its Perl and BioPerl foundations, with stable releases posted to CPAN. Development as well as a publicly accessible Cookbook and Wiki are available on the FAST GitHub repository at https://github.com/tlawrence3/FAST. The default data exchange format in FAST is Multi-FastA (specifically, a restriction of BioPerl FastA format. Sanger and Illumina 1.8+ FastQ formatted files are also supported. FAST makes it easier for non-programmer biologists to interactively investigate and control biological data at the speed of thought.

  6. Anti-HIV drug development on the fast track

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ An international cooperation deal was made recently in Shanghai on developing a new anti-HIV drug based on the research results of CAS scientists and their preclinical studies,marking a breakthrough progress for China's research in the field.

  7. Developing mathematical modelling competence

    DEFF Research Database (Denmark)

    Blomhøj, Morten; Jensen, Tomas Højgaard

    2003-01-01

    In this paper we introduce the concept of mathematical modelling competence, by which we mean being able to carry through a whole mathematical modelling process in a certain context. Analysing the structure of this process, six sub-competences are identified. Mathematical modelling competence...... cannot be reduced to these six sub-competences, but they are necessary elements in the development of mathematical modelling competence. Experience from the development of a modelling course is used to illustrate how the different nature of the sub-competences can be used as a tool for finding...... the balance between different kinds of activities in a particular educational setting. Obstacles of social, cognitive and affective nature for the students' development of mathematical modelling competence are reported and discussed in relation to the sub-competences....

  8. Development of materials and manufacturing technologies for Indian fast reactor programme

    Energy Technology Data Exchange (ETDEWEB)

    Raj, Baldev; Jayakumar, T.; Bhaduri, A.K.; Mandal, Sumantra [Indira Gandhi Centre for Atomic Research, Kalpakkam (India)

    2010-07-01

    Fast Breeder Reactors (FBRs) are vital towards meeting security and sustainability of energy for the growing economy of India. The development of FBRs necessitates extensive research and development in domains of materials and manufacturing technologies in association with a wide spectrum of disciplines and their inter-twining to meet the challenging technology. The paper highlight the work and the approaches adopted for the successful deployment of materials, manufacturing and inspection technologies for the in-core and structural components of current and future Indian Fast Breeder Reactor Programme. Indigenous development of in-core materials viz. Titanium modified austenitic stainless steel (Alloy D9) and its variants, ferritic/martensitic oxide-dispersion strengthened (ODS) steels as well as structural materials viz. 316L(N) stainless steel and modified 9Cr-1Mo have been achieved through synergistic interactions between Indira Gandhi Centre for Atomic Research (IGCAR), education and research institutes and industries. Robust manufacturing technology has been established for forming and joining of various components of 500 MWe Prototype Fast Breeder Reactor (PFBR) through 'science-based technology' approach. To achieve the strict quality standards of formed parts in terms of geometrical tolerances, residual stresses and microstructural defects, FEM-based modelling and experimental validation was carried out for estimation of spring-back during forming of multiple curvature thick plantes. Optimization of grain boundary character distribution in Alloy D9 was carried out by adopting the grain boundary engineering approach to reduce radiation induced segregation. Extensive welding is involved in the fabrication of reactor vessels, piping, steam generators, fuel sub-assemblies etc. Activated Tungsten Inert Gas Welding process along with activated flux developed at IGCAR has been successfully used in fabrication of dummy fuel subassemblies (DFSA) required

  9. Fast and accurate analytical model to solve inverse problem in SHM using Lamb wave propagation

    Science.gov (United States)

    Poddar, Banibrata; Giurgiutiu, Victor

    2016-04-01

    Lamb wave propagation is at the center of attention of researchers for structural health monitoring of thin walled structures. This is due to the fact that Lamb wave modes are natural modes of wave propagation in these structures with long travel distances and without much attenuation. This brings the prospect of monitoring large structure with few sensors/actuators. However the problem of damage detection and identification is an "inverse problem" where we do not have the luxury to know the exact mathematical model of the system. On top of that the problem is more challenging due to the confounding factors of statistical variation of the material and geometric properties. Typically this problem may also be ill posed. Due to all these complexities the direct solution of the problem of damage detection and identification in SHM is impossible. Therefore an indirect method using the solution of the "forward problem" is popular for solving the "inverse problem". This requires a fast forward problem solver. Due to the complexities involved with the forward problem of scattering of Lamb waves from damages researchers rely primarily on numerical techniques such as FEM, BEM, etc. But these methods are slow and practically impossible to be used in structural health monitoring. We have developed a fast and accurate analytical forward problem solver for this purpose. This solver, CMEP (complex modes expansion and vector projection), can simulate scattering of Lamb waves from all types of damages in thin walled structures fast and accurately to assist the inverse problem solver.

  10. Probabilistic modeling of nodal electric vehicle load due to fast charging stations

    DEFF Research Database (Denmark)

    Tang, Difei; Wang, Peng; Wu, Qiuwei

    2016-01-01

    station into consideration. Fuzzy logic inference system is applied to simulate the charging decision of EV drivers at fast charging station. Due to increasing EV loads in power system, the potential traffic congestion in fast charging stations is modeled and evaluated by queuing theory with spatial...

  11. FAST TCP over optical burst switched networks: Modeling and stability analysis

    KAUST Repository

    Shihada, Basem

    2013-04-01

    FAST TCP is important for promoting data-intensive applications since it can cleverly react to both packet loss and delay for detecting network congestion. This paper provides a continuous time model and extensive stability analysis of FAST TCP congestion-control mechanism in bufferless Optical Burst Switched Networks (OBS). The paper first shows that random burst contentions are essential to stabilize the network, but cause throughput degradation in FAST TCP flows when a burst with all the packets from a single round is dropped. Second, it shows that FAST TCP is vulnerable to burst delay and fails to detect network congestion due to the little variation of round-trip time, thus unstable. Finally it shows that introducing extra delays by implementing burst retransmission stabilizes FAST TCP over OBS. The paper proves that FAST TCP is not stable over barebone OBS. However, it is locally, exponentially, and asymptotically stable over OBS with burst retransmission.

  12. Development of fast neutron pinhole camera using nuclear emulsion for neutron emission profile measurement in KSTAR

    Science.gov (United States)

    Izumi, Y.; Tomita, H.; Nakayama, Y.; Hayashi, S.; Morishima, K.; Isobe, M.; Cheon, M. S.; Ogawa, K.; Nishitani, T.; Naka, T.; Nakano, T.; Nakamura, M.; Iguchi, T.

    2016-11-01

    We have developed a compact fast neutron camera based on a stack of nuclear emulsion plates and a pinhole collimator. The camera was installed at J-port of Korea superconducting tokamak advanced research at National Fusion Research Institute, Republic of Korea. Fast neutron images agreed better with calculated ones based on Monte Carlo neutron simulation using the uniform distribution of Deuterium-Deuterium (DD) neutron source in a torus of 40 cm radius.

  13. The Fast Linear Accelerator Modeling Engine for FRIB Online Model Service

    CERN Document Server

    He, Z; Davidsaver, M; Fukushima, K; Shen, G; Ikegami, M

    2016-01-01

    Commissioning of a large accelerator facility like FRIB needs support from an online beam dynamics model. Considering the new physics challenges of FRIB such as modeling of non-axisymmetric superconducting RF cavities and multi-charge state acceleration, there is no readily available online beam tuning code. The design code of FRIB super-conducting linac, IMPACT-Z, is not suitable for online tuning because of its code design and running speed. Therefore, the Fast Linear Accelerator Modeling Engine (FLAME), specifically designed to fulfill FRIB's online modeling challenges, is proposed. The physics model of FLAME, especially its novel way of modeling non-axisymmetric superconducting RF cavities using a multipole expansion based thin-lens kick model, is discussed in detail, and the benchmark results against FRIB design code is presented, after which the software design strategy of FLAME and its execution speed is presented.

  14. Development of level-1 PSA method applicable to Japan Sodium-cooled Fast Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kurisaka, K., E-mail: kurisaka.kennichi@jaea.go.jp [Advanced Nuclear System R and D Directorate, Japan Atomic Energy Agency, Ibaraki (Japan); Sakai, T.; Yamano, H. [Advanced Nuclear System R and D Directorate, Japan Atomic Energy Agency, Ibaraki (Japan); Fujita, S.; Minagawa, K. [Department of Mechanical Engineering, School of Engineering, Tokyo Denki University, Tokyo (Japan); Yamaguchi, A.; Takata, T. [Department of Energy and Environment Engineering, Osaka University, Osaka (Japan)

    2014-04-01

    This paper describes a study to develop the level-1 probabilistic safety assessment (PSA) method that is applicable to the Japan Sodium-cooled Fast Reactor (JSFR). This study has been started since August 2010 and aims to provide a new evaluation method of (1) passive safety architectures related to internal events and (2) an advanced seismic isolation system related to a seismic event as a representative external event in Japan. Regarding the internal events evaluation, a quantitative analysis on the frequency of the core damage caused by reactor shutdown failure was conducted. A failure in passive reactor shutdown was taken into account in the event tree model. The failure rate of sodium-cooled fast reactor (SFR) specific components was evaluated based on the operating experience in existing SFRs by applying the Hierarchical Bayesian Method, which can consider a plant-to-plant variability. By conducting an uncertainty analysis, it was found that the assumption about the correlation of the probability parameters between the main and backup reactor shutdown systems (RSSs) is sensitive to the mean value of the frequency of the core damage caused by reactor shutdown failure. As for the seismic event evaluation, seismic response analysis and sensitivity analysis of a seismic isolation system were carried out. Rubber bearings have a hardening property in horizontal direction and a softening property in vertical direction in case of large deformation. Therefore the analyses considered nonlinearity of rubber bearings. Both horizontal and vertical nonlinear characteristics of rubber bearings were explained by multi-linear model. Mass point analytical models were applied. At first, seismic response analysis was executed in order to investigate influence of nonlinearity of rubber bearing upon response of building. Then sensitivity analysis was executed. Parameters of rubber bearings, oil dampers and the building were fluctuated, and influence of dispersion of these

  15. Modelling Homogeneous Nucleation in Sodium Fast Reactors under BDBA Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, M.; Herranz, L. E.; Kissane, M.

    2014-07-01

    During postulated Beyond Design Basis Accidents (BDBAs) in Sodium-cooled Fast Reactors (SFRs), the contaminated coolant discharge at high temperature into the containment is considered as a potential scenario during the severe accident progression. In this scenario, the vaporization of sodium and its subsequent combustion (oxidation) would result in supersaturated sodium oxide vapours and formation of large quantities of contaminated aerosols by nucleation of these combustion products. (Author)

  16. RISK ANALYSIS DEVELOPED MODEL

    Directory of Open Access Journals (Sweden)

    Georgiana Cristina NUKINA

    2012-07-01

    Full Text Available Through Risk analysis developed model deciding whether control measures suitable for implementation. However, the analysis determines whether the benefits of a data control options cost more than the implementation.

  17. A Fast Electro-Thermal Co-Simulation Modeling Approach for SiC Power MOSFETs

    DEFF Research Database (Denmark)

    Ceccarelli, Lorenzo; Bahman, Amir Sajjad; Iannuzzo, Francesco

    The purpose of this work is to propose a novel electro-thermal co-simulation approach for the new generation of SiC MOSFETs, by development of a PSpice-based compact and physical SiC MOSFET model including temperature dependency of several parameters and a Simulink-based thermal network. The PSpice...... electrical model is capable to estimate the switching behavior and the energy losses of the device accurately under a wide range of operational conditions, including high temperature operations, within a relatively fast simulation time (few seconds). The the thermal network elements are extracted from...... the FEM simulation of the DUT’s structure, performed in ANSYS Icepack. A MATLAB script is used to process the simulation data and feed the needed settings and parameters back into the simulation. The parameters for a CREE 1.2 kV/30 A SiC MOSFET have been identified and the electro-thermal model has been...

  18. The Fast Follower: Coming Up Behind Development Leaders

    Science.gov (United States)

    2015-06-01

    sensitivities to climate change, the global commercial automo- bile industry is running hard to develop the next power source for automobiles . Tesla...DoD faces a shrinking defense industrial base and a more global tech marketplace and competes with the rise of consumer electronics that have short...expensive expeditions of men, ships, wagons, etc., and set off on an uncharted course in search of a vaguely defined goal. After enduring great risk

  19. Chinese RE Performance Materials on the Fast Developing Way

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Rare earth elements are endowed with excellent magnetic, optical and electrical features for their special electronic shell. Series of unsubstitutive advanced materials with prominent performances have been developed, such as magnetic materials, hydrogen storage materials, luminescent materials and catalytic materials, etc. These performance materials are widely used in the fields of metallurgy, oil industry, chemical industry, light industry, agriculture,electronics industry, environmental protection, national defense and some hi-tech advanced materials.

  20. Comparison of models of fast saturable absorption in passively modelocked lasers.

    Science.gov (United States)

    Wang, Shaokang; Marks, Brian S; Menyuk, Curtis R

    2016-09-01

    Fast saturable absorbers (FSAs) play a critical role in stabilizing many passively modelocked lasers. The most commonly used averaged model to study these lasers is the Haus modelocking equation (HME) that includes a third-order nonlinear FSA. However, it predicts a narrow region of stability that is inconsistent with experiments. To better replicate the laser physics, averaged laser models that include FSAs with higher-than-third-order nonlinearities have been introduced. Here, we compare three common FSA models to each other and to the HME using the recently-developed boundary tracking algorithms. The three FSA models are the cubic-quintic model, the sinusoidal model, and the algebraic model. We find that all three models predict the existence of a stable high-energy solution that is not present in the HME and have a much larger stable operating region. We also find that all three models predict qualitatively similar stability diagrams. We conclude that averaged laser models that include FSAs with higher-than-third-order nonlinearity should be used when studying the stability of passively modelocked lasers.

  1. Development of FAST.Farm: A New Multiphysics Engineering Tool for Wind Farm Design and Analysis: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Jonkman, Jason; Annoni, Jennifer; Hayman, Greg; Jonkman, Bonnie; Purkayastha, Avi

    2017-01-01

    This paper presents the development of FAST.Farm, a new multiphysics tool applicable to engineering problems in research and industry involving wind farm performance and cost optimization that is needed to address the current underperformance, failures, and expenses plaguing the wind industry. Achieving wind cost-of-energy targets - which requires improvements in wind farm performance and reliability, together with reduced uncertainty and expenditures - has been eluded by the complicated nature of the wind farm design problem, especially the sophisticated interaction between atmospheric phenomena and wake dynamics and array effects. FAST.Farm aims to balance the need for accurate modeling of the relevant physics for predicting power performance and loads while maintaining low computational cost to support a highly iterative and probabilistic design process and system-wide optimization. FAST.Farm makes use of FAST to model the aero-hydro-servo-elastics of distinct turbines in the wind farm, and it is based on some of the principles of the Dynamic Wake Meandering (DWM) model, but avoids many of the limitations of existing DWM implementations.

  2. Development of FAST.Farm: A New Multiphysics Engineering Tool for Wind-Farm Design and Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Jonkman, Jason; Annoni, Jennifer; Hayman, Greg; Jonkman, Bonnie; Purkayastha, Avi

    2017-01-09

    This paper presents the development of FAST.Farm, a new multiphysics tool applicable to engineering problems in research and industry involving wind farm performance and cost optimization that is needed to address the current underperformance, failures, and expenses plaguing the wind industry. Achieving wind cost-of-energy targets - which requires improvements in wind farm performance and reliability, together with reduced uncertainty and expenditures - has been eluded by the complicated nature of the wind farm design problem, especially the sophisticated interaction between atmospheric phenomena and wake dynamics and array effects. FAST.Farm aims to balance the need for accurate modeling of the relevant physics for predicting power performance and loads while maintaining low computational cost to support a highly iterative and probabilistic design process and system-wide optimization. FAST.Farm makes use of FAST to model the aero-hydro-servo-elastics of distinct turbines in the wind farm, and it is based on some of the principles of the Dynamic Wake Meandering (DWM) model, but avoids many of the limitations of existing DWM implementations.

  3. A Fast and Efficient Version of the TwO-Moment Aerosol Sectional (TOMAS) Global Aerosol Microphysics Model

    Science.gov (United States)

    Lee, Yunha; Adams, P. J.

    2012-01-01

    This study develops more computationally efficient versions of the TwO-Moment Aerosol Sectional (TOMAS) microphysics algorithms, collectively called Fast TOMAS. Several methods for speeding up the algorithm were attempted, but only reducing the number of size sections was adopted. Fast TOMAS models, coupled to the GISS GCM II-prime, require a new coagulation algorithm with less restrictive size resolution assumptions but only minor changes in other processes. Fast TOMAS models have been evaluated in a box model against analytical solutions of coagulation and condensation and in a 3-D model against the original TOMAS (TOMAS-30) model. Condensation and coagulation in the Fast TOMAS models agree well with the analytical solution but show slightly more bias than the TOMAS-30 box model. In the 3-D model, errors resulting from decreased size resolution in each process (i.e., emissions, cloud processing wet deposition, microphysics) are quantified in a series of model sensitivity simulations. Errors resulting from lower size resolution in condensation and coagulation, defined as the microphysics error, affect number and mass concentrations by only a few percent. The microphysics error in CN70CN100 (number concentrations of particles larger than 70100 nm diameter), proxies for cloud condensation nuclei, range from 5 to 5 in most regions. The largest errors are associated with decreasing the size resolution in the cloud processing wet deposition calculations, defined as cloud-processing error, and range from 20 to 15 in most regions for CN70CN100 concentrations. Overall, the Fast TOMAS models increase the computational speed by 2 to 3 times with only small numerical errors stemming from condensation and coagulation calculations when compared to TOMAS-30. The faster versions of the TOMAS model allow for the longer, multi-year simulations required to assess aerosol effects on cloud lifetime and precipitation.

  4. Modelling river dune development

    NARCIS (Netherlands)

    Paarlberg, Andries; Weerts, H.J.T.; Dohmen-Janssen, Catarine M.; Ritsema, I.L; Hulscher, Suzanne J.M.H.; van Os, A.G.; Termes, A.P.P.

    2005-01-01

    Since river dunes influence flow resistance, predictions of dune dimensions are required to make accurate water level predictions. A model approach to simulate developing river dunes is presented. The model is set-up to be appropriate, i.e. as simple as possible, but with sufficient accuracy for

  5. ellc: A fast, flexible light curve model for detached eclipsing binary stars and transiting exoplanets

    Science.gov (United States)

    Maxted, P. F. L.

    2016-06-01

    Context. Very high quality light curves are now available for thousands of detached eclipsing binary stars and transiting exoplanet systems as a result of surveys for transiting exoplanets and other large-scale photometric surveys. Aims: I have developed a binary star model (ellc) that can be used to analyse the light curves of detached eclipsing binary stars and transiting exoplanet systems that is fast and accurate, and that can include the effects of star spots, Doppler boosting and light-travel time within binaries with eccentric orbits. Methods: The model represents the stars as triaxial ellipsoids. The apparent flux from the binary is calculated using Gauss-Legendre integration over the ellipses that are the projection of these ellipsoids on the sky. The model can also be used to calculate the flux-weighted radial velocity of the stars during an eclipse (Rossiter-McLaghlin effect). The main features of the model have been tested by comparison to observed data and other light curve models. Results: The model is found to be accurate enough to analyse the very high quality photometry that is now available from space-spaced instruments, flexible enough to model a wide range of eclipsing binary stars and extrasolar planetary systems, and fast enough to enable the use of modern Monte Carlo methods for data analysis and model testing. The software package is available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/591/A111

  6. Development of time-of-flight neutron detector with fast-decay and low-afterglow scintillator for fast ignition experiment

    Directory of Open Access Journals (Sweden)

    Nagai T.

    2013-11-01

    Full Text Available A fast-decay and low-afterglow liquid scintillator was developed for the fast ignition experiment at the Institute of Laser Engineering (ILE. The liquid scintillator was coupled to a gated photomultiplier (PMT, and the gating performance under high-intensity γ-rays was experimentally checked. In 2010, a detector with a high detection efficiency of 10−4 was developed and installed in this experiment. The neutron yield in the fast heating experiment was successfully measured using this detector.

  7. Development of fast-release solid catchers for rare isotopes

    Science.gov (United States)

    Nolen, Jerry; Greene, John; Elam, Jeffrey; Mane, Anil; Sampathkumaran, Uma; Winter, Raymond; Hess, David; Mushfiq, Mohammad; Stracener, Daniel; Wiendenhoever, Ingo

    2015-04-01

    Porous solid catchers of rare isotopes are being developed for use at high power heavy ion accelerator facilities such as RIKEN, FRIB, and RISP. Compact solid catchers are complementary to helium gas catchers for parasitic harvesting of rare isotopes in the in-flight separators. They are useful for short lived isotopes for basic nuclear physics research and longer-lived isotopes for off-line applications. Solid catchers can operate effectively with high intensity secondary beams, e.g. >> 1E10 atoms/s with release times as short as 10-100 milliseconds. A new method using a very sensitive and efficient RGA has been commissioned off-line at Argonne and is currently being shipped to Florida State University for in-beam measurements of the release curves using stable beams. The same porous solid catcher technology is also being evaluated for use in targets for the production of medical isotopes such as 211-At. Research supported by the U.S. DOE Office of Nuclear Physics under the SBIR Program and Contract # DE-AC02-06CH11357 and a University of Chicago Comprehensive Cancer Center/ANL Pilot Project.

  8. Fokker-Planck/Ray Tracing for Electron Bernstein and Fast Wave Modeling in Support of NSTX

    Energy Technology Data Exchange (ETDEWEB)

    Harvey, R. W. [CompX, Del Mar, CA (United States)

    2009-11-12

    This DOE grant supported fusion energy research, a potential long-term solution to the world's energy needs. Magnetic fusion, exemplified by confinement of very hot ionized gases, i.e., plasmas, in donut-shaped tokamak vessels is a leading approach for this energy source. Thus far, a mixture of hydrogen isotopes has produced 10's of megawatts of fusion power for seconds in a tokamak reactor at Princeton Plasma Physics Laboratory in New Jersey. The research grant under consideration, ER54684, uses computer models to aid in understanding and projecting efficacy of heating and current drive sources in the National Spherical Torus Experiment, a tokamak variant, at PPPL. The NSTX experiment explores the physics of very tight aspect ratio, almost spherical tokamaks, aiming at producing steady-state fusion plasmas. The current drive is an integral part of the steady-state concept, maintaining the magnetic geometry in the steady-state tokamak. CompX further developed and applied models for radiofrequency (rf) heating and current drive for applications to NSTX. These models build on a 30 year development of rf ray tracing (the all-frequencies GENRAY code) and higher dimensional Fokker-Planck rf-collisional modeling (the 3D collisional-quasilinear CQL3D code) at CompX. Two mainline current-drive rf modes are proposed for injection into NSTX: (1) electron Bernstein wave (EBW), and (2) high harmonic fast wave (HHFW) modes. Both these current drive systems provide a means for the rf to access the especially high density plasma--termed high beta plasma--compared to the strength of the required magnetic fields. The CompX studies entailed detailed modeling of the EBW to calculate the efficiency of the current drive system, and to determine its range of flexibility for driving current at spatial locations in the plasma cross-section. The ray tracing showed penetration into NSTX bulk plasma, relatively efficient current drive, but a limited ability to produce current over

  9. Development of a fast gaseous detector: 'Micromegas'

    Energy Technology Data Exchange (ETDEWEB)

    Barouch, G. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Bay, A. [Lausanne University, IPN, BSP, 1015 Dorigny (Switzerland); Bouchigny, S. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Charpak, G. [CERN/LHC, Geneva (Switzerland); Derre, J. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Didierjean, F. [EURISYS Mesures, 1 Chemin de la roseraie, Lingolsheim, 67834 Tanneries Cedex (France); Faivre, J.-C. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Giomataris, Y. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Kochowski, C. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Kunne, F. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Le Goff, J.-M. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Lehar, F. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Lemoigne, Y. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Loucatos, S. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Lugol, J.-C. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Magnon, A. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Mayer, B. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Perroud, J.-P. [Lausanne University, IPN, BSP, 1015 Dorigny (Switzerland); Platchkov, S. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Puill, G. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Rebourgeard, Ph. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Terrien, Y. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Thers, D. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France); Zaccone, H. [CEA/Saclay, DAPNIA, 91191 Gif-sur-Yvette Cedex (France)

    1999-02-21

    Several 15x15 cm{sup 2} gaseous Micromegas chambers (MICROMEsh GAseous Structure) which consist of a conversion gap and an amplification gap separated by a thin grid have been extensively tested in low-intensity 10 GeV/c pion beam and high-intensity (up to 5x10{sup 5} Hz/mm{sup 2}) 100 GeV/c muon beam. The detector behaviour has been studied with respect to many parameters: conversion gaps of 1 and 3 mm, amplification gaps of 50 and 10 {mu}m, an external magnetic field and many different filling gases. So far no effect of the magnetic field up to 1.3 T has been observed. The gas mixture argon + cyclohexane appears to be very suitable with gains above 10{sup 5} and a full-efficiency plateau of 50 V at 340 V. With a conversion gap as small as 1 mm and an electronics with a threshold at 5000 electrons the efficiency reaches 96%. With the addition of CF{sub 4} a time resolution of 5 ns (RMS) has been obtained. A spatial resolution better than 60 {mu}m has been observed with anode strips of 317 {mu}m pitch and was explained by transverse diffusion in the gas. Simulations show that with a pitch of 100 {mu}m and the appropriate gas a resolution of 10 {mu}m is within reach. This development leads to a new generation of cheap position-sensitive detectors which would permit high-precision tracking or vertexing close to the interaction region, in very high-rate environments.

  10. RF Modeling of a Helical Kicker for Fast Chopping

    Energy Technology Data Exchange (ETDEWEB)

    Awida, Mohamed [Fermilab; Chen, Alex [Fermilab; Khabiboulline, Timergali [Fermilab; Saewert, Gregory [Fermilab; Yakovlev, Vyacheslav [Fermilab

    2015-06-01

    High intensity proton particle accelerators that supports several simultaneous physics experiments requires sharing the beam. A bunch by bunch beam chopper system located after the Radio Frequency Quadrupole (RFQ) is required in this case to structure the beam in the proper bunch format required by the several experiments. The unused beam will need to be kicked out of the beam path and is disposed in a beam dumb. In this paper, we report on the RF modeling results of a proposed helical kicker. Two beam kickers constitutes the proposed chopper. The beam sequence is formed by kicking in or out the beam bunches from the streamline. The chopper was developed for Project X Injection Experiment (PXIE).

  11. fast_protein_cluster: parallel and optimized clustering of large-scale protein modeling data.

    Science.gov (United States)

    Hung, Ling-Hong; Samudrala, Ram

    2014-06-15

    fast_protein_cluster is a fast, parallel and memory efficient package used to cluster 60 000 sets of protein models (with up to 550 000 models per set) generated by the Nutritious Rice for the World project. fast_protein_cluster is an optimized and extensible toolkit that supports Root Mean Square Deviation after optimal superposition (RMSD) and Template Modeling score (TM-score) as metrics. RMSD calculations using a laptop CPU are 60× faster than qcprot and 3× faster than current graphics processing unit (GPU) implementations. New GPU code further increases the speed of RMSD and TM-score calculations. fast_protein_cluster provides novel k-means and hierarchical clustering methods that are up to 250× and 2000× faster, respectively, than Clusco, and identify significantly more accurate models than Spicker and Clusco. fast_protein_cluster is written in C++ using OpenMP for multi-threading support. Custom streaming Single Instruction Multiple Data (SIMD) extensions and advanced vector extension intrinsics code accelerate CPU calculations, and OpenCL kernels support AMD and Nvidia GPUs. fast_protein_cluster is available under the M.I.T. license. (http://software.compbio.washington.edu/fast_protein_cluster) © The Author 2014. Published by Oxford University Press.

  12. Interim status report on lead-cooled fast reactor (LFR) research and development.

    Energy Technology Data Exchange (ETDEWEB)

    Tzanos, C. P.; Sienicki, J. J.; Moisseytsev, A.; Smith, C. F.; de Caro, M.; Halsey, W. G.; Li, N.; Hosemann, P.; Zhang, J.; Bolind, A.; LLNL; LANL; Univ. of Illinois

    2008-03-31

    This report discusses the status of Lead-Cooled Fast Reactor (LFR) research and development carried out during the first half of FY 2008 under the U.S. Department of Energy Generation IV Nuclear Energy Systems Initiative. Lead-Cooled Fast Reactor research and development has recently been transferred from Generation IV to the Reactor Campaign of the Global Nuclear Energy Partnership (GNEP). Another status report shall be issued at the end of FY 2008 covering all of the LFR activities carried out in FY 2008 for both Generation IV and GNEP. The focus of research and development in FY 2008 is an initial investigation of a concept for a LFR Advanced Recycling Reactor (ARR) Technology Pilot Plant (TPP)/demonstration test reactor (demo) incorporating features and operating conditions of the European Lead-cooled SYstem (ELSY) {approx} 600 MWe lead (Pb)-cooled LFR preconceptual design for the transmutation of waste and central station power generation, and which would enable irradiation testing of advanced fuels and structural materials. Initial scoping core concept development analyses have been carried out for a 100 MWt core composed of sixteen open-lattice 20 by 20 fuel assemblies largely similar to those of the ELSY preconceptual fuel assembly design incorporating fuel pins with mixed oxide (MOX) fuel, central control rods in each fuel assembly, and cooled with Pb coolant. For a cycle length of three years, the core is calculated to have a conversion ratio of 0.79, an average discharge burnup of 108 MWd/kg of heavy metal, and a burnup reactivity swing of about 13 dollars. With a control rod in each fuel assembly, the reactivity worth of an individual rod would need to be significantly greater than one dollar which is undesirable for postulated rod withdrawal reactivity insertion events. A peak neutron fast flux of 2.0 x 10{sup 15} (n/cm{sup 2}-s) is calculated. For comparison, the 400 MWt Fast Flux Test Facility (FFTF) achieved a peak neutron fast flux of 7.2 x 10{sup

  13. A geometric analysis of fast-slow models for stochastic gene expression.

    Science.gov (United States)

    Popović, Nikola; Marr, Carsten; Swain, Peter S

    2016-01-01

    Stochastic models for gene expression frequently exhibit dynamics on several different scales. One potential time-scale separation is caused by significant differences in the lifetimes of mRNA and protein; the ratio of the two degradation rates gives a natural small parameter in the resulting chemical master equation, allowing for the application of perturbation techniques. Here, we develop a framework for the analysis of a family of 'fast-slow' models for gene expression that is based on geometric singular perturbation theory. We illustrate our approach by giving a complete characterisation of a standard two-stage model which assumes transcription, translation, and degradation to be first-order reactions. In particular, we present a systematic expansion procedure for the probability-generating function that can in principle be taken to any order in the perturbation parameter, allowing for an approximation of the corresponding propagator probabilities to that same order. For illustrative purposes, we perform this expansion explicitly to first order, both on the fast and the slow time-scales; then, we combine the resulting asymptotics into a composite fast-slow expansion that is uniformly valid in time. In the process, we extend, and prove rigorously, results previously obtained by Shahrezaei and Swain (Proc Natl Acad Sci USA 105(45):17256-17261, 2008) and Bokes et al. (J Math Biol 64(5):829-854, 2012; J Math Biol 65(3):493-520, 2012). We verify our asymptotics by numerical simulation, and we explore its practical applicability and the effects of a variation in the system parameters and the time-scale separation. Focussing on biologically relevant parameter regimes that induce translational bursting, as well as those in which mRNA is frequently transcribed, we find that the first-order correction can significantly improve the steady-state probability distribution. Similarly, in the time-dependent scenario, inclusion of the first-order fast asymptotics results in a

  14. Reduction of calcium release site models via fast/slow analysis and iterative aggregation/disaggregation.

    Science.gov (United States)

    Hao, Yan; Kemper, Peter; Smith, Gregory D

    2009-09-01

    Mathematical models of calcium release sites derived from Markov chain models of intracellular calcium channels exhibit collective gating reminiscent of the experimentally observed phenomenon of calcium puffs and sparks. Such models often take the form of stochastic automata networks in which the transition probabilities of each channel depend on the local calcium concentration and thus the state of the other channels. In order to overcome the state-space explosion that occurs in such compositionally defined calcium release site models, we have implemented several automated procedures for model reduction using fast/slow analysis. After categorizing rate constants in the single channel model as either fast or slow, groups of states in the expanded release site model that are connected by fast transitions are lumped, and transition rates between reduced states are chosen consistent with the conditional probability distribution among states within each group. For small problems these conditional probability distributions can be numerically calculated from the full model without approximation. For large problems the conditional probability distributions can be approximated without the construction of the full model by assuming rapid mixing of states connected by fast transitions. Alternatively, iterative aggregation/disaggregation may be employed to obtain reduced calcium release site models in a memory-efficient fashion. Benchmarking of several different iterative aggregation/disaggregation-based fast/slow reduction schemes establishes the effectiveness of automated calcium release site reduction utilizing the Koury-McAllister-Stewart method.

  15. Model for collisional fast ion diffusion into Tokamak Fusion Test Reactor loss cone

    Energy Technology Data Exchange (ETDEWEB)

    Chang, C.S. [New York Univ., NY (United States). Courant Inst. of Mathematical Sciences]|[Korea Advanced Inst. of Science and Technology, Seoul (Korea, Republic of); Zweben, S.J.; Schivell, J.; Budny, R.; Scott, S. [Princeton Univ., NJ (United States). Plasma Physics Lab.

    1994-08-01

    An analytic model is developed to estimate the classical pitch angle scattering loss of energetic fusion product ions into prompt loss orbits in a tokamak geometry. The result is applied to alpha particles produced by deutrium-tritium fusion reactions in a plasma condition relevant to Tokamak Fusion Test Reactor (TFTR). A poloidal angular distribution of collisional fast ion loss at the first wall is obtained and the numerical result from the TRANSP code is discussed. The present model includes the effect that the prompt loss boundary moves away from the slowing-down path due to reduction in banana thickness, which enables us to understand, for the first time. the dependence of the collisional loss rate on Z{sub eff}.

  16. Fast Fourier Transform-based Support Vector Machine for Subcellular Localization Prediction Using Different Substitution Models

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    There are approximately 109 proteins in a cell. A hotspot in bioinformatics is how to identify a protein's subcellular localization, if its sequence is known. In this paper, a method using fast Fourier transform-based support vector machine is developed to predict the subcellular localization of proteins from their physicochemical properties and structural parameters. The prediction accuracies reached 83% in prokaryotic organisms and 84% in eukaryotic organisms with the substitution model of the c-p-v matrix (c, composition; p, polarity; and v, molecular volume). The overall prediction accuracy was also evaluated using the "leave-one-out" jackknife procedure. The influence of the substitution model on prediction accuracy has also been discussed in the work. The source code of the new program is available on request from the authors.

  17. A Tool for Fast Development of Modular and Hierarchic Neural Network-based Systems

    Directory of Open Access Journals (Sweden)

    Francisco Reinaldo

    2006-08-01

    Full Text Available This paper presents PyramidNet tool as a fast and easy way to develop Modular and Hierarchic Neural Network-based Systems. This tool facilitates the fast emergence of autonomous behaviors in agents because it uses a hierarchic and modular control methodology of heterogeneous learning modules: the pyramid. Using the graphical resources of PyramidNet the user is able to specify a behavior system even having little understanding of artificial neural networks. Experimental tests have shown that a very significant speedup is attained in the development of modular and hierarchic neural network-based systems by using this tool.

  18. Software development methodology for computer based I&C systems of prototype fast breeder reactor

    Energy Technology Data Exchange (ETDEWEB)

    Manimaran, M., E-mail: maran@igcar.gov.in; Shanmugam, A.; Parimalam, P.; Murali, N.; Satya Murty, S.A.V.

    2015-10-15

    Highlights: • Software development methodology adopted for computer based I&C systems of PFBR is detailed. • Constraints imposed as part of software requirements and coding phase are elaborated. • Compliance to safety and security requirements are described. • Usage of CASE (Computer Aided Software Engineering) tools during software design, analysis and testing phase are explained. - Abstract: Prototype Fast Breeder Reactor (PFBR) is sodium cooled reactor which is in the advanced stage of construction in Kalpakkam, India. Versa Module Europa bus based Real Time Computer (RTC) systems are deployed for Instrumentation & Control of PFBR. RTC systems have to perform safety functions within the stipulated time which calls for highly dependable software. Hence, well defined software development methodology is adopted for RTC systems starting from the requirement capture phase till the final validation of the software product. V-model is used for software development. IEC 60880 standard and AERB SG D-25 guideline are followed at each phase of software development. Requirements documents and design documents are prepared as per IEEE standards. Defensive programming strategies are followed for software development using C language. Verification and validation (V&V) of documents and software are carried out at each phase by independent V&V committee. Computer aided software engineering tools are used for software modelling, checking for MISRA C compliance and to carry out static and dynamic analysis. Various software metrics such as cyclomatic complexity, nesting depth and comment to code are checked. Test cases are generated using equivalence class partitioning, boundary value analysis and cause and effect graphing techniques. System integration testing is carried out wherein functional and performance requirements of the system are monitored.

  19. KINETIC MODEL OF ELECTRIC-DISCHARGE СО2-LASER WITH FAST FLOW

    Directory of Open Access Journals (Sweden)

    V. Nevdakh

    2013-01-01

    Full Text Available The paper presents a kinetic model of CW electric-discharge CO2-laser with fast flow. Expressions linking a non-saturated gain ratio, saturation intensity and output power of the fast-flow laser with excitation rates and relaxation times of laser levels have been obtained in the paper. The paper demonstrates that the higher excitation and flow rates or higher saturation intensity provide considerably higher specific output power of the fast-flow CO2-laser in comparison with a sealed-off CO2-laser. While maintaining a steady discharge the same output power of the fast-flow CO2-laser may be obtained under various discharge conditions and combinations of fast flow rate, gas mixture composition and active media temperature.

  20. Model reduction for slow-fast stochastic systems with metastable behaviour

    CERN Document Server

    Bruna, Maria; Smith, Matthew J

    2014-01-01

    The quasi-steady-state approximation (or stochastic averaging principle) is a useful tool in the study of multiscale stochastic systems, giving a practical method by which to reduce the number of degrees of freedom in a model. The method is extended here to slow-fast systems in which the fast variables exhibit metastable behaviour. The key parameter that determines the form of the reduced model is the ratio of the timescale for the switching of the fast variables between metastable states to the timescale for the evolution of the slow variables. The method is illustrated with two examples: one from biochemistry (a fast-species-mediated chemical switch coupled to a slower-varying species), and one from ecology (a predator-prey system). Numerical simulations of each model reduction are compared with those of the full system.

  1. Model reduction for slow–fast stochastic systems with metastable behaviour

    Energy Technology Data Exchange (ETDEWEB)

    Bruna, Maria, E-mail: bruna@maths.ox.ac.uk [Mathematical Institute, University of Oxford, Oxford OX2 6GG (United Kingdom); Computational Science Laboratory, Microsoft Research, Cambridge CB1 2FB (United Kingdom); Chapman, S. Jonathan [Mathematical Institute, University of Oxford, Oxford OX2 6GG (United Kingdom); Smith, Matthew J. [Computational Science Laboratory, Microsoft Research, Cambridge CB1 2FB (United Kingdom)

    2014-05-07

    The quasi-steady-state approximation (or stochastic averaging principle) is a useful tool in the study of multiscale stochastic systems, giving a practical method by which to reduce the number of degrees of freedom in a model. The method is extended here to slow–fast systems in which the fast variables exhibit metastable behaviour. The key parameter that determines the form of the reduced model is the ratio of the timescale for the switching of the fast variables between metastable states to the timescale for the evolution of the slow variables. The method is illustrated with two examples: one from biochemistry (a fast-species-mediated chemical switch coupled to a slower varying species), and one from ecology (a predator–prey system). Numerical simulations of each model reduction are compared with those of the full system.

  2. GPU-based ultra fast dose calculation using a finite pencil beam model

    CERN Document Server

    Gu, Xuejun; Men, Chunhua; Pan, Hubert; Majumdar, Amitava; Jiang, Steve B

    2009-01-01

    Online adaptive radiation therapy (ART) is an attractive concept that promises the ability to deliver an optimal treatment in response to the inter-fraction variability in patient anatomy. However, it has yet to be realized due to technical limitations. Fast dose deposit coefficient calculation is a critical component of the online planning process that is required for plan optimization of intensity modulated radiation therapy (IMRT). Computer graphics processing units (GPUs) are well-suited to provide the requisite fast performance for the data-parallel nature of dose calculation. In this work, we develop a dose calculation engine based on a finite-size pencil beam (FSPB) algorithm and a GPU parallel computing framework. The developed framework can accommodate any FSPB model. We test our implementation on a case of a water phantom and a case of a prostate cancer patient with varying beamlet and voxel sizes. All testing scenarios achieved speedup ranging from 200~400 times when using a NVIDIA Tesla C1060 card...

  3. A CFD model for biomass fast pyrolysis in fluidized-bed reactors

    Science.gov (United States)

    Xue, Qingluan; Heindel, T. J.; Fox, R. O.

    2010-11-01

    A numerical study is conducted to evaluate the performance and optimal operating conditions of fluidized-bed reactors for fast pyrolysis of biomass to bio-oil. A comprehensive CFD model, coupling a pyrolysis kinetic model with a detailed hydrodynamics model, is developed. A lumped kinetic model is applied to describe the pyrolysis of biomass particles. Variable particle porosity is used to account for the evolution of particle physical properties. The kinetic scheme includes primary decomposition and secondary cracking of tar. Biomass is composed of reference components: cellulose, hemicellulose, and lignin. Products are categorized into groups: gaseous, tar vapor, and solid char. The particle kinetic processes and their interaction with the reactive gas phase are modeled with a multi-fluid model derived from the kinetic theory of granular flow. The gas, sand and biomass constitute three continuum phases coupled by the interphase source terms. The model is applied to investigate the effect of operating conditions on the tar yield in a fluidized-bed reactor. The influence of various parameters on tar yield, including operating temperature and others are investigated. Predicted optimal conditions for tar yield and scale-up of the reactor are discussed.

  4. Simulating polar bear energetics during a seasonal fast using a mechanistic model.

    Directory of Open Access Journals (Sweden)

    Paul D Mathewson

    Full Text Available In this study we tested the ability of a mechanistic model (Niche Mapper™ to accurately model adult, non-denning polar bear (Ursus maritimus energetics while fasting during the ice-free season in the western Hudson Bay. The model uses a steady state heat balance approach, which calculates the metabolic rate that will allow an animal to maintain its core temperature in its particular microclimate conditions. Predicted weight loss for a 120 day fast typical of the 1990s was comparable to empirical studies of the population, and the model was able to reach a heat balance at the target metabolic rate for the entire fast, supporting use of the model to explore the impacts of climate change on polar bears. Niche Mapper predicted that all but the poorest condition bears would survive a 120 day fast under current climate conditions. When the fast extended to 180 days, Niche Mapper predicted mortality of up to 18% for males. Our results illustrate how environmental conditions, variation in animal properties, and thermoregulation processes may impact survival during extended fasts because polar bears were predicted to require additional energetic expenditure for thermoregulation during a 180 day fast. A uniform 3°C temperature increase reduced male mortality during a 180 day fast from 18% to 15%. Niche Mapper explicitly links an animal's energetics to environmental conditions and thus can be a valuable tool to help inform predictions of climate-related population changes. Since Niche Mapper is a generic model, it can make energetic predictions for other species threatened by climate change.

  5. Calibration and validation of a spar-type floating offshore wind turbine model using the FAST dynamic simulation tool

    Science.gov (United States)

    Browning, J. R.; Jonkman, J.; Robertson, A.; Goupee, A. J.

    2014-12-01

    High-quality computer simulations are required when designing floating wind turbines because of the complex dynamic responses that are inherent with a high number of degrees of freedom and variable metocean conditions. In 2007, the FAST wind turbine simulation tool, developed and maintained by the U.S. Department of Energy's (DOE's) National Renewable Energy Laboratory (NREL), was expanded to include capabilities that are suitable for modeling floating offshore wind turbines. In an effort to validate FAST and other offshore wind energy modeling tools, DOE funded the DeepCwind project that tested three prototype floating wind turbines at 1/50th scale in a wave basin, including a semisubmersible, a tension-leg platform, and a spar buoy. This paper describes the use of the results of the spar wave basin tests to calibrate and validate the FAST offshore floating simulation tool, and presents some initial results of simulated dynamic responses of the spar to several combinations of wind and sea states. Wave basin tests with the spar attached to a scale model of the NREL 5-megawatt reference wind turbine were performed at the Maritime Research Institute Netherlands under the DeepCwind project. This project included free-decay tests, tests with steady or turbulent wind and still water (both periodic and irregular waves with no wind), and combined wind/wave tests. The resulting data from the 1/50th model was scaled using Froude scaling to full size and used to calibrate and validate a full-size simulated model in FAST. Results of the model calibration and validation include successes, subtleties, and limitations of both wave basin testing and FAST modeling capabilities.

  6. FAST Mast Structural Response to Axial Loading: Modeling and Verification

    Science.gov (United States)

    Knight, Norman F., Jr.; Elliott, Kenny B.; Templeton, Justin D.; Song, Kyongchan; Rayburn, Jeffery T.

    2012-01-01

    The International Space Station s solar array wing mast shadowing problem is the focus of this paper. A building-block approach to modeling and analysis is pursued for the primary structural components of the solar array wing mast structure. Starting with an ANSYS (Registered Trademark) finite element model, a verified MSC.Nastran (Trademark) model is established for a single longeron. This finite element model translation requires the conversion of several modeling and analysis features for the two structural analysis tools to produce comparable results for the single-longeron configuration. The model is then reconciled using test data. The resulting MSC.Nastran (Trademark) model is then extended to a single-bay configuration and verified using single-bay test data. Conversion of the MSC. Nastran (Trademark) single-bay model to Abaqus (Trademark) is also performed to simulate the elastic-plastic longeron buckling response of the single bay prior to folding.

  7. Fast All-Sky Radiation Model for Solar Applications (FARMS): A Brief Overview of Mechanisms, Performance, and Applications: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Xie, Yu; Sengupta, Manajit

    2016-06-01

    Solar radiation can be computed using radiative transfer models, such as the Rapid Radiation Transfer Model (RRTM) and its general circulation model applications, and used for various energy applications. Due to the complexity of computing radiation fields in aerosol and cloudy atmospheres, simulating solar radiation can be extremely time-consuming, but many approximations--e.g., the two-stream approach and the delta-M truncation scheme--can be utilized. To provide a new fast option for computing solar radiation, we developed the Fast All-sky Radiation Model for Solar applications (FARMS) by parameterizing the simulated diffuse horizontal irradiance and direct normal irradiance for cloudy conditions from the RRTM runs using a 16-stream discrete ordinates radiative transfer method. The solar irradiance at the surface was simulated by combining the cloud irradiance parameterizations with a fast clear-sky model, REST2. To understand the accuracy and efficiency of the newly developed fast model, we analyzed FARMS runs using cloud optical and microphysical properties retrieved using GOES data from 2009-2012. The global horizontal irradiance for cloudy conditions was simulated using FARMS and RRTM for global circulation modeling with a two-stream approximation and compared to measurements taken from the U.S. Department of Energy's Atmospheric Radiation Measurement Climate Research Facility Southern Great Plains site. Our results indicate that the accuracy of FARMS is comparable to or better than the two-stream approach; however, FARMS is approximately 400 times more efficient because it does not explicitly solve the radiative transfer equation for each individual cloud condition. Radiative transfer model runs are computationally expensive, but this model is promising for broad applications in solar resource assessment and forecasting. It is currently being used in the National Solar Radiation Database, which is publicly available from the National Renewable Energy

  8. ELLC - a fast, flexible light curve model for detached eclipsing binary stars and transiting exoplanets

    CERN Document Server

    Maxted, P F L

    2016-01-01

    Very high quality light curves are now available for thousands of detached eclipsing binary stars and transiting exoplanet systems as a result of surveys for transiting exoplanets and other large-scale photometric surveys. I have developed a binary star model (ELLC) that can be used to analyse the light curves of detached eclipsing binary stars and transiting exoplanet systems that is fast and accurate, and that can include the effects of star spots, Doppler boosting and light-travel time within binaries with eccentric orbits. The model represents the stars as triaxial ellipsoids. The apparent flux from the binary is calculated using Gauss-Legendre integration over the ellipses that are the projection of these ellipsoids on the sky. The model can also be used to calculate the flux-weighted radial velocity of the stars during an eclipse (Rossiter-McLaughlin effect). The main features of the model have tested by comparison to observed data and other light curve models. The model is found to be accurate enough t...

  9. Effects of fast-velocity eccentric resistance training on early and late rate of force development

    DEFF Research Database (Denmark)

    Oliveira, Anderson S.C.; Corvino, Rogério Bulhões; Caputo, Fabrizio

    2016-01-01

    This study examined whether short-term maximal resistance training employing fast-velocity eccentric knee extensor actions would induce improvements in maximal isometric torque and rate of force development (RFD) at early (100 ms) of rising torque. Twenty healthy men were...

  10. Fast Automatic Precision Tree Models from Terrestrial Laser Scanner Data

    Directory of Open Access Journals (Sweden)

    Mathias Disney

    2013-01-01

    Full Text Available This paper presents a new method for constructing quickly and automatically precision tree models from point clouds of the trunk and branches obtained by terrestrial laser scanning. The input of the method is a point cloud of a single tree scanned from multiple positions. The surface of the visible parts of the tree is robustly reconstructed by making a flexible cylinder model of the tree. The thorough quantitative model records also the topological branching structure. In this paper, every major step of the whole model reconstruction process, from the input to the finished model, is presented in detail. The model is constructed by a local approach in which the point cloud is covered with small sets corresponding to connected surface patches in the tree surface. The neighbor-relations and geometrical properties of these cover sets are used to reconstruct the details of the tree and, step by step, the whole tree. The point cloud and the sets are segmented into branches, after which the branches are modeled as collections of cylinders. From the model, the branching structure and size properties, such as volume and branch size distributions, for the whole tree or some of its parts, can be approximated. The approach is validated using both measured and modeled terrestrial laser scanner data from real trees and detailed 3D models. The results show that the method allows an easy extraction of various tree attributes from terrestrial or mobile laser scanning point clouds.

  11. A proposed Fast algorithm to construct the system matrices for a reduced-order groundwater model

    Science.gov (United States)

    Ushijima, Timothy T.; Yeh, William W.-G.

    2017-04-01

    Past research has demonstrated that a reduced-order model (ROM) can be two-to-three orders of magnitude smaller than the original model and run considerably faster with acceptable error. A standard method to construct the system matrices for a ROM is Proper Orthogonal Decomposition (POD), which projects the system matrices from the full model space onto a subspace whose range spans the full model space but has a much smaller dimension than the full model space. This projection can be prohibitively expensive to compute if it must be done repeatedly, as with a Monte Carlo simulation. We propose a Fast Algorithm to reduce the computational burden of constructing the system matrices for a parameterized, reduced-order groundwater model (i.e. one whose parameters are represented by zones or interpolation functions). The proposed algorithm decomposes the expensive system matrix projection into a set of simple scalar-matrix multiplications. This allows the algorithm to efficiently construct the system matrices of a POD reduced-order model at a significantly reduced computational cost compared with the standard projection-based method. The developed algorithm is applied to three test cases for demonstration purposes. The first test case is a small, two-dimensional, zoned-parameter, finite-difference model; the second test case is a small, two-dimensional, interpolated-parameter, finite-difference model; and the third test case is a realistically-scaled, two-dimensional, zoned-parameter, finite-element model. In each case, the algorithm is able to accurately and efficiently construct the system matrices of the reduced-order model.

  12. Development of a fixed abrasive slicing technique (FAST) for reducing the cost of photovoltaic wafers

    Energy Technology Data Exchange (ETDEWEB)

    Schmid, F. (Crystal Systems, Inc., Salem, MA (United States))

    1991-12-01

    This report examines a wafer slicing technique developed by Crystal Systems, Inc. that reduces the cost of photovoltaic wafers. This fixed, abrasive slicing technique (FAST) uses a multiwire bladepack and a diamond-plated wirepack; water is the coolant. FAST is in the prototype production stage and reduces expendable material costs while retaining the advantages of a multiwire slurry technique. The cost analysis revealed that costs can be decreased by making more cuts per bladepack and slicing more wafers per linear inch. Researchers studied the degradation of bladepacks and increased wirepack life. 21 refs.

  13. Product Development Process Modeling

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    The use of Concurrent Engineering and other modern methods of product development and maintenance require that a large number of time-overlapped "processes" be performed by many people. However, successfully describing and optimizing these processes are becoming even more difficult to achieve. The perspective of industrial process theory (the definition of process) and the perspective of process implementation (process transition, accumulation, and inter-operations between processes) are used to survey the method used to build one base model (multi-view) process model.

  14. Internal model control of a fast steering mirror for electro-optical fine tracking

    Science.gov (United States)

    Xia, Yun-xia; Bao, Qi-liang; Wu, Qiong-yan

    2010-11-01

    The objective of this research is to develop advanced control methods to improve the bandwidth and tracking precision of the electro-optical fine tracking system using a fast steering mirror (FSM). FSM is the most important part in this control system. The model of FSM is established at the beginning of this paper. Compared with the electro-optical fine tracking system with ground based platform, the electro-optical fine tracking system with movement based platform must be a wide bandwidth and a robustness system. An advanced control method based on internal model control law is developed for electro-optical fine tracking system. The IMC is an advanced algorithm. Theoretically, it can eliminate disturbance completely and make sure output equals to input even there is model error. Moreover, it separates process to the system dynamic characteristic and the object perturbation. Compared with the PID controller, the controller is simpler and the parameter regulation is more convenient and the system is more robust. In addition, we design an improved structure based on classic IMC. The tracking error of the two-port control system is much better than which of the classic IMC. The simulation results indicate that the electro-optical control system based on the internal model control algorithm is very effective. It shows a better performance at the tracing precision and the disturbance suppresses. Thus a new method is provided for the high-performance electro-optical fine tracking system.

  15. Development of Fast Algorithms Using Recursion, Nesting and Iterations for Computational Electromagnetics

    Science.gov (United States)

    Chew, W. C.; Song, J. M.; Lu, C. C.; Weedon, W. H.

    1995-01-01

    In the first phase of our work, we have concentrated on laying the foundation to develop fast algorithms, including the use of recursive structure like the recursive aggregate interaction matrix algorithm (RAIMA), the nested equivalence principle algorithm (NEPAL), the ray-propagation fast multipole algorithm (RPFMA), and the multi-level fast multipole algorithm (MLFMA). We have also investigated the use of curvilinear patches to build a basic method of moments code where these acceleration techniques can be used later. In the second phase, which is mainly reported on here, we have concentrated on implementing three-dimensional NEPAL on a massively parallel machine, the Connection Machine CM-5, and have been able to obtain some 3D scattering results. In order to understand the parallelization of codes on the Connection Machine, we have also studied the parallelization of 3D finite-difference time-domain (FDTD) code with PML material absorbing boundary condition (ABC). We found that simple algorithms like the FDTD with material ABC can be parallelized very well allowing us to solve within a minute a problem of over a million nodes. In addition, we have studied the use of the fast multipole method and the ray-propagation fast multipole algorithm to expedite matrix-vector multiplication in a conjugate-gradient solution to integral equations of scattering. We find that these methods are faster than LU decomposition for one incident angle, but are slower than LU decomposition when many incident angles are needed as in the monostatic RCS calculations.

  16. Development of taste masked fast disintegrating films of levocetirizine dihydrochloride for oral use.

    Science.gov (United States)

    Mahesh, A; Shastri, Nalini; Sadanandam, M

    2010-01-01

    Fast disintegrating films of levocetirizine dihydrochloride useful for the treatment of acute allergic rhinitis and chronic urticaria have been developed by using the taste masking ability of cyclodextrins. The fast disintegrating films were prepared by solvent casting method. The films contained water-soluble polymers such as Kollicoat IR or pullulan, aspartame and sucralose as sweeteners and pre-gelatinized starch as disintegrant. Levocetirizine dihydrochloride was incorporated into these films by in-situ complex formation with hydroxy propyl beta-cyclodextrin. The optimized films were evaluated for weight variation, film thickness, folding endurance, tackiness, tensile strength, assay, content uniformity, in vitro disintegration and dissolution, in vivo disintegration and taste masking ability by human gustatory sensation test. Results revealed that the organoleptic properties of levocetirizine dihydrochloride were improved by complexation with hydroxy propyl beta-cyclodextrin and the complex could be successfully formulated into a fast disintegrating film.

  17. Development of a fast DNA extraction method for sea food and marine species identification.

    Science.gov (United States)

    Tagliavia, Marcello; Nicosia, Aldo; Salamone, Monica; Biondo, Girolama; Bennici, Carmelo Daniele; Mazzola, Salvatore; Cuttitta, Angela

    2016-07-15

    The authentication of food components is one of the key issues in food safety. Similarly taxonomy, population and conservation genetics as well as food web structure analysis, also rely on genetic analyses including the DNA barcoding technology. In this scenario we developed a fast DNA extraction method without any purification step from fresh and processed seafood, suitable for any PCR analysis. The protocol allows the fast DNA amplification from any sample, including fresh, stored and processed seafood and from any waste of industrial fish processing, independently of the sample storage method. Therefore, this procedure is particularly suitable for the fast processing of samples and to carry out investigations for the authentication of seafood by means of DNA analysis. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Development of fast measurements of concentration of NORM U-238 by HPGe

    Science.gov (United States)

    Cha, Seokki; Kim, Siu; Kim, Geehyun

    2017-02-01

    Naturally Occureed Radioactive Material (NORM) generated from the origin of earth can be found all around us and even people who are not engaged in the work related to radiation have been exposed to unnecessary radiation. This NORM has a potential risk provided that is concentrated or transformed by artificial activities. Likewise, a development of fast measruement method of NORM is emerging to prevent the radiation exposure of the general public and person engaged in the work related to the type of business related thereto who uses the material in which NORM is concentrated or transfromed. Based on such a background, many of countries have tried to manage NORM and carried out regulatory legislation. To effienctly manage NORM, there is need for developing new measurement to quickly and accurately analyze the nuclide and concentration. In this study, development of the fast and reliable measurement was carried out. In addition to confirming the reliability of the fast measurement, we have obtained results that can suggest the possibility of developing another fast measurement. Therefore, as a follow-up, it is possible to develop another fast analytical measurement afterwards. The results of this study will be very useful for the regulatory system to manage NORM. In this study, a review of two indirect measurement methods of NORM U-238 that has used HPGe on the basis of the equilibrium theory of relationships of mother and daughter nuclide at decay-chain of NORM U-238 has been carried out. For comparative study(in order to know reliabily), direct measurement that makes use of alpha spectrometer with complicated pre-processing process was implemented.

  19. NASA AVOSS Fast-Time Models for Aircraft Wake Prediction: User's Guide (APA3.8 and TDP2.1)

    Science.gov (United States)

    Ahmad, Nash'at N.; VanValkenburg, Randal L.; Pruis, Matthew J.; Limon Duparcmeur, Fanny M.

    2016-01-01

    NASA's current distribution of fast-time wake vortex decay and transport models includes APA (Version 3.8) and TDP (Version 2.1). This User's Guide provides detailed information on the model inputs, file formats, and model outputs. A brief description of the Memphis 1995, Dallas/Fort Worth 1997, and the Denver 2003 wake vortex datasets is given along with the evaluation of models. A detailed bibliography is provided which includes publications on model development, wake field experiment descriptions, and applications of the fast-time wake vortex models.

  20. A performance model for the communication in fast multipole methods on high-performance computing platforms

    KAUST Repository

    Ibeid, Huda

    2016-03-04

    Exascale systems are predicted to have approximately 1 billion cores, assuming gigahertz cores. Limitations on affordable network topologies for distributed memory systems of such massive scale bring new challenges to the currently dominant parallel programing model. Currently, there are many efforts to evaluate the hardware and software bottlenecks of exascale designs. It is therefore of interest to model application performance and to understand what changes need to be made to ensure extrapolated scalability. The fast multipole method (FMM) was originally developed for accelerating N-body problems in astrophysics and molecular dynamics but has recently been extended to a wider range of problems. Its high arithmetic intensity combined with its linear complexity and asynchronous communication patterns make it a promising algorithm for exascale systems. In this paper, we discuss the challenges for FMM on current parallel computers and future exascale architectures, with a focus on internode communication. We focus on the communication part only; the efficiency of the computational kernels are beyond the scope of the present study. We develop a performance model that considers the communication patterns of the FMM and observe a good match between our model and the actual communication time on four high-performance computing (HPC) systems, when latency, bandwidth, network topology, and multicore penalties are all taken into account. To our knowledge, this is the first formal characterization of internode communication in FMM that validates the model against actual measurements of communication time. The ultimate communication model is predictive in an absolute sense; however, on complex systems, this objective is often out of reach or of a difficulty out of proportion to its benefit when there exists a simpler model that is inexpensive and sufficient to guide coding decisions leading to improved scaling. The current model provides such guidance.

  1. Recent Developments In Fast Neutron Detection And Multiplicity Counting With Verification With Liquid Scintillator

    Energy Technology Data Exchange (ETDEWEB)

    Nakae, L; Chapline, G; Glenn, A; Kerr, P; Kim, K; Ouedraogo, S; Prasad, M; Sheets, S; Snyderman, N; Verbeke, J; Wurtz, R

    2011-09-30

    For many years at LLNL, we have been developing time-correlated neutron detection techniques and algorithms for applications such as Arms Control, Threat Detection and Nuclear Material Assay. Many of our techniques have been developed specifically for the relatively low efficiency (a few percent) attainable by detector systems limited to man-portability. Historically, we used thermal neutron detectors (mainly {sup 3}He), taking advantage of the high thermal neutron interaction cross-sections. More recently, we have been investigating the use of fast neutron detection with liquid scintillators, inorganic crystals, and in the near future, pulse-shape discriminating plastics which respond over 1000 times faster (nanoseconds versus tens of microseconds) than thermal neutron detectors. Fast neutron detection offers considerable advantages, since the inherent nanosecond production time-scales of spontaneous fission and neutron-induced fission are preserved and measured instead of being lost by thermalization required for thermal neutron detectors. We are now applying fast neutron technology to the safeguards regime in the form of fast portable digital electronics as well as faster and less hazardous scintillator formulations. Faster detector response times and sensitivity to neutron momentum show promise for measuring, differentiating, and assaying samples that have modest to very high count rates, as well as mixed fission sources like Cm and Pu. We report on measured results with our existing liquid scintillator array, and progress on the design of a nuclear material assay system that incorporates fast neutron detection, including the surprising result that fast liquid scintillator detectors become competitive and even surpass the precision of {sup 3}He-based counters measuring correlated pairs in modest (kg) samples of plutonium.

  2. Recent Developments in Fast Neutron Detection and Multiplicity Counting with Liquid Scintillator

    Science.gov (United States)

    Nakae, L. F.; Chapline, G. F.; Glenn, A. M.; Kerr, P. L.; Kim, K. S.; Ouedraogo, S. A.; Prasad, M. K.; Sheets, S. A.; Snyderman, N. J.; Verbeke, J. M.; Wurtz, R. E.

    2011-12-01

    For many years, LLNL researchers have been developing time-correlated neutron detection techniques and algorithms for applications such as Arms Control, Threat Detection and Nuclear Material Assay. Many of the techniques have been developed specifically for the relatively low efficiency (a few percent) attainable by detector systems limited to man-portability. Historically, thermal neutron detectors (mainly 3He) were used, taking advantage of the high thermal neutron interaction cross sections. More recently, we have been investigating the use of fast neutron detection with liquid scintillators, inorganic crystals, and in the near future, pulse-shape discriminating plastics that respond over 1000 times faster (ns versus tens of μs) than thermal neutron detectors. Fast neutron detection offers considerable advantages since the inherent ns production timescales of spontaneous fission and neutron-induced fission are preserved and measured instead of being lost by thermalization required for thermal neutron detectors. We are now applying fast neutron technology to the safeguards regime in the form of fast portable digital electronics as well as faster and less hazardous scintillator formulations. Faster detector response times and sensitivity to neutron momentum show promise for measuring, differentiating, and assaying samples that have modest to very high count rates, as well as mixed fission sources like Cm and Pu. We report on measured results with our existing liquid scintillator array and progress on the design of a nuclear material assay system that incorporates fast neutron detection, including the surprising result that fast liquid scintillator detectors become competitive and even surpass the precision of 3He-based counters measuring correlated pairs in modest (kg) samples of plutonium.

  3. Integrated Computational Model Development

    Science.gov (United States)

    2014-03-01

    68.5%, 9.6% and 21.9%, respectively. The alloy density and Vickers microhardness were ρ = 8.23 ± 0.01 g/cm3 and Hv = 5288 ± 1 MPa. [3...and 3-D. Techniques to mechanically test materials at smaller scales were developed to better inform the deformation models. Also methods were...situ microscale tension testing technique was adapted to enable microscale fatigue testing on tensile dog-bone specimens. Microscale tensile fatigue

  4. A Constraint Programming Model for Fast Optimal Stowage of Container Vessel Bays

    DEFF Research Database (Denmark)

    Delgado-Ortegon, Alberto; Jensen, Rune Møller; Janstrup, Kira

    representative model of them developed with our industrial partner and a constraint programming (CP) and integer programming approach to solve them optimally. Our experimental evaluation of 236 instances extracted from real stowage plans shows that, even though these sub-problems are theoretically hard...... bays. Due to the large number of sub-problems, they must each be solved fast to generate complete stowage plans within the time requirements and computational resource limits of the shipping industry. In this paper we present the first independent study of these sub-problems. We introduce an accurate......Container vessel stowage is a combinatorial optimization problem with both high economic and environmental impact. The most successful approaches to tackle this problem use hierarchical decompositions in which the sub-problems of these decompositions assign containers to slots in individual vessel...

  5. Developing a Model Component

    Science.gov (United States)

    Fields, Christina M.

    2013-01-01

    The Spaceport Command and Control System (SCCS) Simulation Computer Software Configuration Item (CSCI) is responsible for providing simulations to support test and verification of SCCS hardware and software. The Universal Coolant Transporter System (UCTS) was a Space Shuttle Orbiter support piece of the Ground Servicing Equipment (GSE). The initial purpose of the UCTS was to provide two support services to the Space Shuttle Orbiter immediately after landing at the Shuttle Landing Facility. The UCTS is designed with the capability of servicing future space vehicles; including all Space Station Requirements necessary for the MPLM Modules. The Simulation uses GSE Models to stand in for the actual systems to support testing of SCCS systems during their development. As an intern at Kennedy Space Center (KSC), my assignment was to develop a model component for the UCTS. I was given a fluid component (dryer) to model in Simulink. I completed training for UNIX and Simulink. The dryer is a Catch All replaceable core type filter-dryer. The filter-dryer provides maximum protection for the thermostatic expansion valve and solenoid valve from dirt that may be in the system. The filter-dryer also protects the valves from freezing up. I researched fluid dynamics to understand the function of my component. The filter-dryer was modeled by determining affects it has on the pressure and velocity of the system. I used Bernoulli's Equation to calculate the pressure and velocity differential through the dryer. I created my filter-dryer model in Simulink and wrote the test script to test the component. I completed component testing and captured test data. The finalized model was sent for peer review for any improvements. I participated in Simulation meetings and was involved in the subsystem design process and team collaborations. I gained valuable work experience and insight into a career path as an engineer.

  6. Reduced Fast Ion Transport Model For The Tokamak Transport Code TRANSP

    Energy Technology Data Exchange (ETDEWEB)

    Podesta,, Mario; Gorelenkova, Marina; White, Roscoe

    2014-02-28

    Fast ion transport models presently implemented in the tokamak transport code TRANSP [R. J. Hawryluk, in Physics of Plasmas Close to Thermonuclear Conditions, CEC Brussels, 1 , 19 (1980)] are not capturing important aspects of the physics associated with resonant transport caused by instabilities such as Toroidal Alfv en Eigenmodes (TAEs). This work describes the implementation of a fast ion transport model consistent with the basic mechanisms of resonant mode-particle interaction. The model is formulated in terms of a probability distribution function for the particle's steps in phase space, which is consistent with the MonteCarlo approach used in TRANSP. The proposed model is based on the analysis of fast ion response to TAE modes through the ORBIT code [R. B. White et al., Phys. Fluids 27 , 2455 (1984)], but it can be generalized to higher frequency modes (e.g. Compressional and Global Alfv en Eigenmodes) and to other numerical codes or theories.

  7. One-Dimensional Biomass Fast Pyrolysis Model with Reaction Kinetics Integrated in an Aspen Plus Biorefinery Process Model

    Energy Technology Data Exchange (ETDEWEB)

    Humbird, David; Trendewicz, Anna; Braun, Robert; Dutta, Abhijit

    2017-01-27

    A biomass fast pyrolysis reactor model with detailed reaction kinetics and one-dimensional fluid dynamics was implemented in an equation-oriented modeling environment (Aspen Custom Modeler). Portions of this work were detailed in previous publications; further modifications have been made here to improve stability and reduce execution time of the model to make it compatible for use in large process flowsheets. The detailed reactor model was integrated into a larger process simulation in Aspen Plus and was stable for different feedstocks over a range of reactor temperatures. Sample results are presented that indicate general agreement with experimental results, but with higher gas losses caused by stripping of the bio-oil by the fluidizing gas in the simulated absorber/condenser. This integrated modeling approach can be extended to other well-defined, predictive reactor models for fast pyrolysis, catalytic fast pyrolysis, as well as other processes.

  8. CRLH Transmission Lines for Telecommunications: Fast and Effective Modeling

    Directory of Open Access Journals (Sweden)

    Juanjuan Gao

    2017-01-01

    Full Text Available A different parameter extraction approach based on zero immittances for composite right/left-handed (CRLH structure is presented. For lossless unit cell equivalent circuit model, LC parameters of series and parallel branches are extracted according to series resonance frequency and parallel resonance frequency, respectively. This approach can be applied to symmetric and unbalanced CRLH structures. The parameter extraction procedure is provided and validated by T-type unit cell model. The responses of distributed prototype and extracted equivalent LC circuit model are in good agreement. The equivalent circuit modeling can improve the degree of freedom in the CRLH TLs design. This parameter extraction method provides an effective and straightforward way in CRLH metamaterials design and applications in telecommunication systems.

  9. Fast and simple model for atmospheric radiative transfer

    NARCIS (Netherlands)

    Seidel, F.C.; Kokhanovsky, A.A.; Schaepman, M.E.

    2010-01-01

    Radiative transfer models (RTMs) are of utmost importance for quantitative remote sensing, especially for compensating atmospheric perturbation. A persistent trade-off exists between approaches that prefer accuracy at the cost of computational complexity, versus those favouring simplicity at the

  10. Fast sampling model for X-ray Rayleigh scattering

    CERN Document Server

    Grichine, V M

    2013-01-01

    A simple model for X-ray Rayleigh scattering is discussed in terms of the process total cross-section and the angular distribution of scattered X-ray photons. Comparisons with other calculations and experimental data are presented. The model is optimized for the simulation of X-ray tracking inside experimental setups with complex geometry where performance and memory volume are issues to be optimized. (C) 2013 Elsevier B.V. All rights reserved.

  11. Fast, Automated, 3D Modeling of Building Interiors

    Science.gov (United States)

    2012-10-30

    Cheng, M. Anderson, S. He, A. Zakhor, "Texture Mapping 3D Planar Models of Indoor Environments with Noisy Camera Poses," SPIE electronic imaging...successfully process noisy scans with non-zero registration error. Most of the processing is performed after a dramatic dimensionality reduction, yielding a...lobby and hallways of a hotel .  Applying textures to these models is an important step in generating photorealistic visualizations of data

  12. Fast Adaptation in Generative Models with Generative Matching Networks

    OpenAIRE

    Bartunov, Sergey; Vetrov, Dmitry P.

    2016-01-01

    Despite recent advances, the remaining bottlenecks in deep generative models are necessity of extensive training and difficulties with generalization from small number of training examples. Both problems may be addressed by conditional generative models that are trained to adapt the generative distribution to additional input data. So far this idea was explored only under certain limitations such as restricting the input data to be a single object or multiple objects representing the same con...

  13. Fast weak-lensing simulations with halo model

    Science.gov (United States)

    Giocoli, Carlo; Di Meo, Sandra; Meneghetti, Massimo; Jullo, Eric; de la Torre, Sylvain; Moscardini, Lauro; Baldi, Marco; Mazzotta, Pasquale; Metcalf, R. Benton

    2017-09-01

    Full ray-tracing maps of gravitational lensing, constructed from N-body simulations, represent a fundamental tool to interpret present and future weak-lensing data. However, the limitation of computational resources and storage capabilities severely restricts the number of realizations that can be performed in order to accurately sample both the cosmic shear models and covariance matrices. In this paper, we present a halo model formalism for weak gravitational lensing that alleviates these issues by producing weak-lensing mocks at a reduced computational cost. Our model takes as input the halo population within a desired light cone and the linear power spectrum of the underlined cosmological model. We examine the contribution given by the presence of substructures within haloes to the cosmic shear power spectrum and quantify it to the percent level. Our method allows us to reconstruct high-resolution convergence maps, for any desired source redshifts, of light cones that realistically trace the matter density distribution in the universe, account for masked area and sample selections. We compare our analysis on the same large-scale structures constructed using ray-tracing techniques and find very good agreements in both the linear and non-linear regimes up to few percent levels. The accuracy and speed of our method demonstrate the potential of our halo model for weak-lensing statistics and the possibility to generate a large sample of convergence maps for different cosmological models as needed for the analysis of large galaxy redshift surveys.

  14. Simulation of earthquake caused building damages for the development of fast reconnaissance techniques

    Directory of Open Access Journals (Sweden)

    C. Schweier

    2004-01-01

    Full Text Available Catastrophic events like strong earthquakes can cause big losses in life and economic values. An increase in the efficiency of reconnaissance techniques could help to reduce the losses in life as many victims die after and not during the event. A basic prerequisite to improve the rescue teams' work is an improved planning of the measures. This can only be done on the basis of reliable and detailed information about the actual situation in the affected regions. Therefore, a bundle of projects at Karlsruhe university aim at the development of a tool for fast information retrieval after strong earthquakes. The focus is on urban areas as the most losses occur there. In this paper the approach for a damage analysis of buildings will be presented. It consists of an automatic methodology to model buildings in three dimensions, a comparison of pre- and post-event models to detect changes and a subsequent classification of the changes into damage types. The process is based on information extraction from airborne laserscanning data, i.e. digital surface models (DSM acquired through scanning of an area with pulsed laser light. To date, there are no laserscanning derived DSMs available to the authors that were taken of areas that suffered damages from earthquakes. Therefore, it was necessary to simulate such data for the development of the damage detection methodology. In this paper two different methodologies used for simulating the data will be presented. The first method is to create CAD models of undamaged buildings based on their construction plans and alter them artificially in such a way as if they had suffered serious damage. Then, a laserscanning data set is simulated based on these models which can be compared with real laserscanning data acquired of the buildings (in intact state. The other approach is to use measurements of actual damaged buildings and simulate their intact state. It is possible to model the geometrical structure of these

  15. Regulatory Technology Development Plan Sodium Fast Reactor. Mechanistic Source Term Development

    Energy Technology Data Exchange (ETDEWEB)

    Grabaskas, David S. [Argonne National Lab. (ANL), Argonne, IL (United States); Brunett, Acacia Joann [Argonne National Lab. (ANL), Argonne, IL (United States); Bucknor, Matthew D. [Argonne National Lab. (ANL), Argonne, IL (United States); Sienicki, James J. [Argonne National Lab. (ANL), Argonne, IL (United States); Sofu, Tanju [Argonne National Lab. (ANL), Argonne, IL (United States)

    2015-02-28

    Construction and operation of a nuclear power installation in the U.S. requires licensing by the U.S. Nuclear Regulatory Commission (NRC). A vital part of this licensing process and integrated safety assessment entails the analysis of a source term (or source terms) that represents the release of radionuclides during normal operation and accident sequences. Historically, nuclear plant source term analyses have utilized deterministic, bounding assessments of the radionuclides released to the environment. Significant advancements in technical capabilities and the knowledge state have enabled the development of more realistic analyses such that a mechanistic source term (MST) assessment is now expected to be a requirement of advanced reactor licensing. This report focuses on the state of development of an MST for a sodium fast reactor (SFR), with the intent of aiding in the process of MST definition by qualitatively identifying and characterizing the major sources and transport processes of radionuclides. Due to common design characteristics among current U.S. SFR vendor designs, a metal-fuel, pool-type SFR has been selected as the reference design for this work, with all phenomenological discussions geared toward this specific reactor configuration. This works also aims to identify the key gaps and uncertainties in the current knowledge state that must be addressed for SFR MST development. It is anticipated that this knowledge state assessment can enable the coordination of technology and analysis tool development discussions such that any knowledge gaps may be addressed. Sources of radionuclides considered in this report include releases originating both in-vessel and ex-vessel, including in-core fuel, primary sodium and cover gas cleanup systems, and spent fuel movement and handling. Transport phenomena affecting various release groups are identified and qualitatively discussed, including fuel pin and primary coolant retention, and behavior in the cover gas and

  16. Advanced model for fast assessment of piezoelectric micro energy harvesters

    Directory of Open Access Journals (Sweden)

    Raffaele eArdito

    2016-04-01

    Full Text Available The purpose of this work is to present recent advances in modelling and design of piezoelectric energy harvesters, in the framework of Micro-Electro-Mechanical Systems (MEMS. More specifically, the case of inertial energy harvesting is considered, in the sense that the kinetic energy due to environmental vibration is transformed into electrical energy by means of piezoelectric transduction. The execution of numerical analyses is greatly important in order to predict the actual behaviour of MEMS devices and to carry out the optimization process. In the common practice, the results are obtained by means of burdensome 3D Finite Element Analyses (FEA.The case of beams could be treated by applying 1D models, which can enormously reduce the computational burden with obvious benefits in the case of repeated analyses. Unfortunately, the presence of piezoelectric coupling may entail some serious issues in view of its intrinsically three-dimensional behaviour. In this paper, a refined, yet simple, model is proposed with the objective of retaining the Euler-Bernoulli beam model, with the inclusion of effects connected to the actual three-dimensional shape of the device. The proposed model is adopted to evaluate the performances of realistic harvesters, both in the case of harmonic excitation and for impulsive loads.

  17. Towards a Fast Dynamic Model of the Human Circulatory System

    Science.gov (United States)

    Kaplan, Carolyn; Green, Melissa; Boris, Jay; Oran, Elaine

    2011-11-01

    We describe a model for systems-level transport in the human circulatory system that is based on a set of equations for a one-dimensional unsteady elastic pipe flow circuit. The system is collapsed from three spatial dimensions and time to one spatial dimension and time by assuming axisymmetric vessel geometry and a parabolic velocity profile across the cylindrical vessels. To drive the fluid, the contractions of a beating heart are modeled as periodic area changes of the elastic vessels. Two different models are compared, both including and neglecting fluid acceleration. Time-resolved distributions of pressure, velocity and area compare reasonably well with reference data. Increasing the rigidity of the vasculature is found to increase peak arterial pressures on the order of ten percent, and including a distributed vascular contraction to model distributed skeletal muscle contractions monotonically increases time-averaged blood flow in the veins, consistent with human physiological response. The circulatory system model presented here simulates the circulatory system on the order of one hundred times faster than real-time; that is, we can compute thousands of heartbeats per minute of CPU time.

  18. Fast neutrino decay in the minimal seesaw model

    CERN Document Server

    Joshipura, A S; Joshipura, Anjans S.; Rindani, Saurabh D.

    1992-01-01

    Neutrino decay in the minimal seesaw model containing three right handed neutrinos and a complex $SU(2)\\times U(1)$ singlet Higgs in addition to the standard model fields is considered. A global horizontal symmetry $U(1)_H$ is imposed, which on spontaneous breaking gives rise to a Goldstone boson. This symmetry is chosen in a way that makes a) the contribution of heavy ($\\leq$ MeV) majorana neutrinos to the neutrinoless double beta decay amplitude vanish and b) allows the heavy neutrino to decay to a lighter neutrino and the Goldstone boson. It is shown that this decay can occur at a rate much faster than in the original Majoron model even if one does not introduce any additional Higgs fields as is done in the literature. Possibility of describing the 17 keV neutrino in this minimal seesaw model is investigated. While most of the cosmological and astrophysical constraints on the 17 keV neutrino can be satisfied in this model, the laboratory limits coming from the neutrino oscillations cannot be easily met. An...

  19. Advanced model for fast assessment of piezoelectric micro energy harvesters

    Science.gov (United States)

    Ardito, Raffaele; Corigliano, Alberto; Gafforelli, Giacomo; Valzasina, Carlo; Procopio, Francesco; Zafalon, Roberto

    2016-04-01

    The purpose of this work is to present recent advances in modelling and design of piezoelectric energy harvesters, in the framework of Micro-Electro-Mechanical Systems (MEMS). More specifically, the case of inertial energy harvesting is considered, in the sense that the kinetic energy due to environmental vibration is transformed into electrical energy by means of piezoelectric transduction. The execution of numerical analyses is greatly important in order to predict the actual behaviour of MEMS devices and to carry out the optimization process. In the common practice, the results are obtained by means of burdensome 3D Finite Element Analyses (FEA). The case of beams could be treated by applying 1D models, which can enormously reduce the computational burden with obvious benefits in the case of repeated analyses. Unfortunately, the presence of piezoelectric coupling may entail some serious issues in view of its intrinsically three-dimensional behaviour. In this paper, a refined, yet simple, model is proposed with the objective of retaining the Euler-Bernoulli beam model, with the inclusion of effects connected to the actual three-dimensional shape of the device. The proposed model is adopted to evaluate the performances of realistic harvesters, both in the case of harmonic excitation and for impulsive loads.

  20. Modelling of Moving Coil Actuators in Fast Switching Valves Suitable for Digital Hydraulic Machines

    DEFF Research Database (Denmark)

    Nørgård, Christian; Roemer, Daniel Beck; Bech, Michael Møller

    2015-01-01

    an estimation of the eddy currents generated in the actuator yoke upon current rise, as they may have significant influence on the coil current response. The analytical model facilitates fast simulation of the transient actuator response opposed to the transient electro-magnetic finite element model which...

  1. Formulation Development and Characterization of Meclizine Hydrochloride Sublimated Fast Dissolving Tablets.

    Science.gov (United States)

    Vemula, Sateesh Kumar; Vangala, Mohan

    2014-01-01

    The intention of present research is to formulate and develop the meclizine hydrochloride fast dissolving tablets using sublimation method to enhance the dissolution rate. In this study an attempt was made to fasten the drug release from the oral tablets by incorporating the superdisintegrants and camphor as sublimating agent. The prepared fast dissolving tablets were subjected to precompression properties and characterized for hardness, weight variation, friability, wetting time, water absorption ratio, and disintegration time. From in vitro release studies, the formulation F9 exhibited fast release profile of about 98.61% in 30 min, and disintegration time 47 sec when compared with other formulations. The percent drug release in 30 min (Q 30) and initial dissolution rate for formulation F9 was 98.61 ± 0.25%, 3.29%/min. These were very much higher compared to marketed tablets (65.43 ± 0.57%, 2.18%/min). The dissolution efficiency was found to be 63.37 and it is increased by 1.4-fold with F9 FDT tablets compared to marketed tablets. Differential scanning calorimetry and Fourier transform infrared spectroscopy studies revealed that there was no possibility of interactions. Thus the development of meclizine hydrochloride fast dissolving tablets by sublimation method is a suitable approach to improve the dissolution rate.

  2. Kinetic models for historical processes of fast invasion and aggression

    Science.gov (United States)

    Aristov, Vladimir V.; Ilyin, Oleg V.

    2015-04-01

    In the last few decades many investigations have been devoted to theoretical models in new areas concerning description of different biological, sociological, and historical processes. In the present paper we suggest a model of the Nazi Germany invasion of Poland, France, and the USSR based on kinetic theory. We simulate this process with the Cauchy boundary problem for two-element kinetic equations. The solution of the problem is given in the form of a traveling wave. The propagation velocity of a front line depends on the quotient between initial forces concentrations. Moreover it is obtained that the general solution of the model can be expressed in terms of quadratures and elementary functions. Finally it is shown that the front-line velocities agree with the historical data.

  3. Universal real-time control framework and Internet of Things for fast-paced research and development based production environments

    KAUST Repository

    Chaoui, Hicham

    2017-05-13

    This paper introduces a universal real-time control platform for complex research and development (R&D) based products design. The inherent complexity in R&D projects makes products development a difficult task to undertake. The use of state of the art development tools for modeling, simulation, and hardware-in-the-loop (HIL) validation contributes to a complexity reduction. However, R&D projects still require significant development time since many design iterations are usually necessary before final solution, which increases the cost. In most R&D processes, these tools are not used beyond rapid prototyping since development for mass production is usually performed in another environment, using different tools. This paper presents a fast and cost effective way of R&D-based products development, speeding-up time to market.

  4. Personalized heterogeneous deformable model for fast volumetric registration.

    Science.gov (United States)

    Si, Weixin; Liao, Xiangyun; Wang, Qiong; Heng, Pheng Ann

    2017-02-20

    Biomechanical deformable volumetric registration can help improve safety of surgical interventions by ensuring the operations are extremely precise. However, this technique has been limited by the accuracy and the computational efficiency of patient-specific modeling. This study presents a tissue-tissue coupling strategy based on penalty method to model the heterogeneous behavior of deformable body, and estimate the personalized tissue-tissue coupling parameters in a data-driven way. Moreover, considering that the computational efficiency of biomechanical model is highly dependent on the mechanical resolution, a practical coarse-to-fine scheme is proposed to increase runtime efficiency. Particularly, a detail enrichment database is established in an offline fashion to represent the mapping relationship between the deformation results of high-resolution hexahedral mesh extracted from the raw medical data and a newly constructed low-resolution hexahedral mesh. At runtime, the mechanical behavior of human organ under interactions is simulated with this low-resolution hexahedral mesh, then the microstructures are synthesized in virtue of the detail enrichment database. The proposed method is validated by volumetric registration in an abdominal phantom compression experiments. Our personalized heterogeneous deformable model can well describe the coupling effects between different tissues of the phantom. Compared with high-resolution heterogeneous deformable model, the low-resolution deformable model with our detail enrichment database can achieve 9.4× faster, and the average target registration error is 3.42 mm, which demonstrates that the proposed method shows better volumetric registration performance than state-of-the-art. Our framework can well balance the precision and efficiency, and has great potential to be adopted in the practical augmented reality image-guided robotic systems.

  5. IMPACT fragmentation model developments

    Science.gov (United States)

    Sorge, Marlon E.; Mains, Deanna L.

    2016-09-01

    The IMPACT fragmentation model has been used by The Aerospace Corporation for more than 25 years to analyze orbital altitude explosions and hypervelocity collisions. The model is semi-empirical, combining mass, energy and momentum conservation laws with empirically derived relationships for fragment characteristics such as number, mass, area-to-mass ratio, and spreading velocity as well as event energy distribution. Model results are used for several types of analysis including assessment of short-term risks to satellites from orbital altitude fragmentations, prediction of the long-term evolution of the orbital debris environment and forensic assessments of breakup events. A new version of IMPACT, version 6, has been completed and incorporates a number of advancements enabled by a multi-year long effort to characterize more than 11,000 debris fragments from more than three dozen historical on-orbit breakup events. These events involved a wide range of causes, energies, and fragmenting objects. Special focus was placed on the explosion model, as the majority of events examined were explosions. Revisions were made to the mass distribution used for explosion events, increasing the number of smaller fragments generated. The algorithm for modeling upper stage large fragment generation was updated. A momentum conserving asymmetric spreading velocity distribution algorithm was implemented to better represent sub-catastrophic events. An approach was developed for modeling sub-catastrophic explosions, those where the majority of the parent object remains intact, based on estimated event energy. Finally, significant modifications were made to the area-to-mass ratio distribution to incorporate the tendencies of different materials to fragment into different shapes. This ability enabled better matches between the observed area-to-mass ratios and those generated by the model. It also opened up additional possibilities for post-event analysis of breakups. The paper will discuss

  6. Fast Filtering and Smoothing for Multivariate State Space Models

    NARCIS (Netherlands)

    Koopman, S.J.M.; Durbin, J.

    1998-01-01

    This paper gives a new approach to diffuse filtering and smoothing for multivariate state space models. The standard approach treats the observations as vectors while our approach treats each element of the observational vector individually. This strategy leads to computationally efficient methods f

  7. Modeling of Dynamic Fluid Forces in Fast Switching Valves

    DEFF Research Database (Denmark)

    Roemer, Daniel Beck; Johansen, Per; Pedersen, Henrik Clemmensen;

    2015-01-01

    force, but these models are computationally expensive and are not suitable for evaluating large numbers of different operation conditions or even design optimization. In the present paper, an effort is done to describe these fluid forces and their origin. An example of the total opposing fluid force...

  8. The MAPPINGS III Library of Fast Radiative Shock Models

    CERN Document Server

    Allen, Mark G; Dopita, Michael A; Sutherland, Ralph S; Kewley, Lisa J

    2008-01-01

    We present a new library of fully-radiative shock models calculated with the MAPPINGS III shock and photoionization code. The library consists of grids of models with shock velocities in the range v=100-1000 km/s and magnetic parameters B/sqrt(n) of 10^-4 - 10 muG cm^(3/2) for five different atomic abundance sets, and for a pre-shock density of 1.0 cm^(-3). Additionally, Solar abundance model grids have been calculated for densities of 0.01, 0.1, 10, 100, and 1000 cm^(-3) with the same range in v and B/sqrt(n). Each model includes components of both the radiative shock and its photoionized precursor, ionized by the EUV and soft X-ray radiation generated in the radiative gas. We present the details of the ionization structure, the column densities, and the luminosities of the shock and its precursor. Emission line ratio predictions are separately given for the shock and its precursor as well as for the composite shock+precursor structure to facilitate comparison with observations in cases where the shock and i...

  9. Fast and simple model for atmospheric radiative transfer

    NARCIS (Netherlands)

    Seidel, F.C.; Kokhanovsky, A.A.; Schaepman, M.E.

    2010-01-01

    Radiative transfer models (RTMs) are of utmost importance for quantitative remote sensing, especially for compensating atmospheric perturbation. A persistent trade-off exists between approaches that prefer accuracy at the cost of computational complexity, versus those favouring simplicity at the cos

  10. Development of a GPU Compatible Version of the Fast Radiation Code RRTMG

    Science.gov (United States)

    Iacono, M. J.; Mlawer, E. J.; Berthiaume, D.; Cady-Pereira, K. E.; Suarez, M.; Oreopoulos, L.; Lee, D.

    2012-12-01

    The absorption of solar radiation and emission/absorption of thermal radiation are crucial components of the physics that drive Earth's climate and weather. Therefore, accurate radiative transfer calculations are necessary for realistic climate and weather simulations. Efficient radiation codes have been developed for this purpose, but their accuracy requirements still necessitate that as much as 30% of the computational time of a GCM is spent computing radiative fluxes and heating rates. The overall computational expense constitutes a limitation on a GCM's predictive ability if it becomes an impediment to adding new physics to or increasing the spatial and/or vertical resolution of the model. The emergence of Graphics Processing Unit (GPU) technology, which will allow the parallel computation of multiple independent radiative calculations in a GCM, will lead to a fundamental change in the competition between accuracy and speed. Processing time previously consumed by radiative transfer will now be available for the modeling of other processes, such as physics parameterizations, without any sacrifice in the accuracy of the radiative transfer. Furthermore, fast radiation calculations can be performed much more frequently and will allow the modeling of radiative effects of rapid changes in the atmosphere. The fast radiation code RRTMG, developed at Atmospheric and Environmental Research (AER), is utilized operationally in many dynamical models throughout the world. We will present the results from the first stage of an effort to create a version of the RRTMG radiation code designed to run efficiently in a GPU environment. This effort will focus on the RRTMG implementation in GEOS-5. RRTMG has an internal pseudo-spectral vector of length of order 100 that, when combined with the much greater length of the global horizontal grid vector from which the radiation code is called in GEOS-5, makes RRTMG/GEOS-5 particularly suited to achieving a significant speed improvement

  11. Fast and slow responses of Southern Ocean sea surface temperature to SAM in coupled climate models

    Science.gov (United States)

    Kostov, Yavor; Marshall, John; Hausmann, Ute; Armour, Kyle C.; Ferreira, David; Holland, Marika M.

    2017-03-01

    We investigate how sea surface temperatures (SSTs) around Antarctica respond to the Southern Annular Mode (SAM) on multiple timescales. To that end we examine the relationship between SAM and SST within unperturbed preindustrial control simulations of coupled general circulation models (GCMs) included in the Climate Modeling Intercomparison Project phase 5 (CMIP5). We develop a technique to extract the response of the Southern Ocean SST (55°S-70°S) to a hypothetical step increase in the SAM index. We demonstrate that in many GCMs, the expected SST step response function is nonmonotonic in time. Following a shift to a positive SAM anomaly, an initial cooling regime can transition into surface warming around Antarctica. However, there are large differences across the CMIP5 ensemble. In some models the step response function never changes sign and cooling persists, while in other GCMs the SST anomaly crosses over from negative to positive values only 3 years after a step increase in the SAM. This intermodel diversity can be related to differences in the models' climatological thermal ocean stratification in the region of seasonal sea ice around Antarctica. Exploiting this relationship, we use observational data for the time-mean meridional and vertical temperature gradients to constrain the real Southern Ocean response to SAM on fast and slow timescales.

  12. Evaluation of Fast-Time Wake Vortex Models using Wake Encounter Flight Test Data

    Science.gov (United States)

    Ahmad, Nashat N.; VanValkenburg, Randal L.; Bowles, Roland L.; Limon Duparcmeur, Fanny M.; Gloudesman, Thijs; van Lochem, Sander; Ras, Eelco

    2014-01-01

    This paper describes a methodology for the integration and evaluation of fast-time wake models with flight data. The National Aeronautics and Space Administration conducted detailed flight tests in 1995 and 1997 under the Aircraft Vortex Spacing System Program to characterize wake vortex decay and wake encounter dynamics. In this study, data collected during Flight 705 were used to evaluate NASA's fast-time wake transport and decay models. Deterministic and Monte-Carlo simulations were conducted to define wake hazard bounds behind the wake generator. The methodology described in this paper can be used for further validation of fast-time wake models using en-route flight data, and for determining wake turbulence constraints in the design of air traffic management concepts.

  13. Fluctuation-Response Relation and modeling in systems with fast and slow dynamics

    Directory of Open Access Journals (Sweden)

    G. Lacorata

    2007-10-01

    Full Text Available We show how a general formulation of the Fluctuation-Response Relation is able to describe in detail the connection between response properties to external perturbations and spontaneous fluctuations in systems with fast and slow variables. The method is tested by using the 360-variable Lorenz-96 model, where slow and fast variables are coupled to one another with reciprocal feedback, and a simplified low dimensional system. In the Fluctuation-Response context, the influence of the fast dynamics on the slow dynamics relies in a non trivial behavior of a suitable quadratic response function. This has important consequences for the modeling of the slow dynamics in terms of a Langevin equation: beyond a certain intrinsic time interval even the optimal model can give just statistical prediction.

  14. Fast, Sequence Adaptive Parcellation of Brain MR Using Parametric Models

    DEFF Research Database (Denmark)

    Puonti, Oula; Iglesias, Juan Eugenio; Van Leemput, Koen

    2013-01-01

    -of-the-art segmentation performance in both cortical and subcortical structures, while retaining all the benefits of generative parametric models, including high computational speed, automatic adaptiveness to changes in image contrast when different scanner platforms and pulse sequences are used, and the ability......In this paper we propose a method for whole brain parcellation using the type of generative parametric models typically used in tissue classification. Compared to the non-parametric, multi-atlas segmentation techniques that have become popular in recent years, our method obtains state...... to handle multi-contrast (vector-valued intensities) MR data. We have validated our method by comparing its segmentations to manual delineations both within and across scanner platforms and pulse sequences, and show preliminary results on multi-contrast test-retest scans, demonstrating the feasibility...

  15. A Fast, Affordable, Science and Technology SATellite (FASTSAT) and the Small Satellite Market Development Environment

    Science.gov (United States)

    Boudreaux, Mark; Montgomery, Edward; Cacas, Joseph

    2008-01-01

    The National Aeronautics and Space Administr ation at Marshall Space Flight Center and the National Space Science and Technology Center in Huntsville Alabama USA, are jointly developing a new class of science and technology mission small satellites. The Fast, Affordable, Science and Technology SATell ite (FASTSAT) was designed and developed using a new collaborative and best practices approach. The FASTSAT development, along with the new class of low cost vehicles currently being developed, would allow performance of 30 kg payload mass missions for a cost of less than 10 million US dollars.

  16. A fast ellipsoid model for asteroids inverted from lightcurves

    Institute of Scientific and Technical Information of China (English)

    Xiao-Ping Lu; Hai-Bin Zhao; Zhong You

    2013-01-01

    Research about asteroids has recently attracted more and more attention,especially focusing on their physical structures,such as their spin axis,rotation period and shape.The long distance between observers on Earth and asteroids makes it impossible to directly calculate the shape and other parameters of asteroids,with the exception of Near Earth Asteroids and others that have passed by some spacecrafts.Photometric measurements are still generally the main way to obtain research data on asteroids,i.e.the lightcurves recording the brightness and positions of asteroids.Supposing that the shape of the asteroid is a triaxial ellipsoid with a stable spin,a new method is presented in this article to reconstruct the shape models of asteroids from the lightcurves,together with other physical parameters.By applying a special curvature function,the method calculates the brightness integration on a unit sphere and Lebedev quadrature is employed for the discretization.Finally,the method searches for the optimal solution by the Levenberg-Marquardt algorithm to minimize the residual of the brightness.By adopting this method,not only can related physical parameters of asteroids be obtained at a reasonable accuracy,but also a simple shape model of an ellipsoid can be generated for reconstructing a more sophisticated shape model.

  17. Fast Ray Tracing of Lunar Digital Elevation Models

    Science.gov (United States)

    McClanahan, Timothy P.; Evans, L. G.; Starr, R. D.; Mitrofanov, I.

    2009-01-01

    Ray-tracing (RT) of Lunar Digital Elevation Models (DEM)'s is performed to virtually derive the degree of radiation incident to terrain as a function of time, orbital and ephemeris constraints [I- 4]. This process is an integral modeling process in lunar polar research and exploration due to the present paucity of terrain information at the poles and mission planning activities for the anticipated spring 2009 launch of the Lunar Reconnaissance Orbiter (LRO). As part of the Lunar Exploration Neutron Detector (LEND) and Lunar Crater Observation and Sensing Satellite (LCROSS) preparations RI methods are used to estimate the critical conditions presented by the combined effects of high latitude, terrain and the moons low obliquity [5-7]. These factors yield low incident solar illumination and subsequently extreme thermal, and radiation conditions. The presented research uses RT methods both for radiation transport modeling in space and regolith related research as well as to derive permanently shadowed regions (PSR)'s in high latitude topographic minima, e.g craters. These regions are of scientific and human exploration interest due to the near constant low temperatures in PSRs, inferred to be < 100 K. Hydrogen is thought to have accumulated in PSR's through the combined effects of periodic cometary bombardment and/or solar wind processes, and the extreme cold which minimizes hydrogen sublimation [8-9]. RT methods are also of use in surface position optimization for future illumination dependent on surface resources e.g. power and communications equipment.

  18. Fast coarse-grained model for RNA titration

    Science.gov (United States)

    Barroso da Silva, Fernando Luís; Derreumaux, Philippe; Pasquali, Samuela

    2017-01-01

    A new numerical scheme for RNA (ribonucleic acid) titration based on the Debye-Hückel framework for the salt description is proposed in an effort to reduce the computational costs for further applications to study protein-RNA systems. By means of different sets of Monte Carlo simulations, we demonstrated that this new scheme is able to correctly reproduce the experimental titration behavior and salt pKa shifts. In comparison with other theoretical approaches, similar or even better outcomes are achieved at much lower computational costs. The model was tested on the lead-dependent ribozyme, the branch-point helix, and the domain 5 from Azotobacter vinelandii Intron 5.

  19. Development and Reliability Testing of a Fast-Food Restaurant Observation Form.

    Science.gov (United States)

    Rimkus, Leah; Ohri-Vachaspati, Punam; Powell, Lisa M; Zenk, Shannon N; Quinn, Christopher M; Barker, Dianne C; Pugach, Oksana; Resnick, Elissa A; Chaloupka, Frank J

    2015-01-01

    To develop a reliable observational data collection instrument to measure characteristics of the fast-food restaurant environment likely to influence consumer behaviors, including product availability, pricing, and promotion. The study used observational data collection. Restaurants were in the Chicago Metropolitan Statistical Area. A total of 131 chain fast-food restaurant outlets were included. Interrater reliability was measured for product availability, pricing, and promotion measures on a fast-food restaurant observational data collection instrument. Analysis was done with Cohen's κ coefficient and proportion of overall agreement for categorical variables and intraclass correlation coefficient (ICC) for continuous variables. Interrater reliability, as measured by average κ coefficient, was .79 for menu characteristics, .84 for kids' menu characteristics, .92 for food availability and sizes, .85 for beverage availability and sizes, .78 for measures on the availability of nutrition information,.75 for characteristics of exterior advertisements, and .62 and .90 for exterior and interior characteristics measures, respectively. For continuous measures, average ICC was .88 for food pricing measures, .83 for beverage prices, and .65 for counts of exterior advertisements. Over 85% of measures demonstrated substantial or almost perfect agreement. Although some measures required revision or protocol clarification, results from this study suggest that the instrument may be used to reliably measure the fast-food restaurant environment.

  20. A new fast reconnection model in a collisionless regime

    CERN Document Server

    Tsiklauri, David

    2008-01-01

    Based on the first principles (by balancing the advection with the electron pressure tensor in the generalised Ohm's law, and using the conservation of mass) a simple model of magnetic reconnection in a collisionless regime is formulated. In addition to its importance from the fundamental point of view, the collisionless reconnection model offers a much faster reconnection rate ($M_{c'less}={(d_i/2)}^{1/2}$) than Sweet-Parker's classical one ($M_{sp}=S^{-1/2}$). The width of the diffusion region (current sheet) in the collisionless regime is found to be $\\delta_{c'less}={(d_i/2)}^{1/2}L$, which is much larger than the Sweet-Parker width ($\\delta_{sp}=S^{-1/2}L$) for the space plasma conditions. Amongst other issues, this alleviates e.g. the problem of interpretation of solar flares by means of reconnection, as for the typical solar coronal parameters the obtained collisionless reconnection time can be $< 10$ minutes, as opposed to Sweet-Parker's equivalent value of $<$ year. The new theoretical reconnec...

  1. Fast and simple model for atmospheric radiative transfer

    Directory of Open Access Journals (Sweden)

    F. C. Seidel

    2010-05-01

    Full Text Available Radiative transfer models (RTMs are of utmost importance for quantitative remote sensing, especially for compensating atmospheric perturbation. A persistent trade-off exists between approaches that prefer accuracy at the cost of computational complexity, versus those favouring simplicity at the cost of reduced accuracy. We propose an approach in the latter category, using analytical equations, parameterizations and a correction factor to efficiently estimate the effect of molecular multiple scattering. We discuss the approximations together with an analysis of the resulting performance and accuracy. The proposed Simple Model for Atmospheric Radiative Transfer (SMART decreases the calculation time by a factor of more than 25 in comparison to the benchmark RTM~6S on the same infrastructure. The approximative computation of the atmospheric reflectance factor by SMART has an uncertainty ranging from about 5% to 10% for nadir spaceborne and airborne observational conditions. The combination of a large solar zenith angle (SZA with high aerosol optical depth (AOD at low wavelengths lead to uncertainties of up to 15%. SMART can be used to simulate the hemispherical conical reflectance factor (HCRF for spaceborne and airborne sensors, as well as for the retrieval of columnar AOD.

  2. Neurobiological model of stimulated dopamine neurotransmission to interpret fast-scan cyclic voltammetry data.

    Science.gov (United States)

    Harun, Rashed; Grassi, Christine M; Munoz, Miranda J; Torres, Gonzalo E; Wagner, Amy K

    2015-03-02

    Fast-scan cyclic voltammetry (FSCV) is an electrochemical method that can assess real-time in vivo dopamine (DA) concentration changes to study the kinetics of DA neurotransmission. Electrical stimulation of dopaminergic (DAergic) pathways can elicit FSCV DA responses that largely reflect a balance of DA release and reuptake. Interpretation of these evoked DA responses requires a framework to discern the contribution of DA release and reuptake. The current, widely implemented interpretive framework for doing so is the Michaelis-Menten (M-M) model, which is grounded on two assumptions- (1) DA release rate is constant during stimulation, and (2) DA reuptake occurs through dopamine transporters (DAT) in a manner consistent with M-M enzyme kinetics. Though the M-M model can simulate evoked DA responses that rise convexly, response types that predominate in the ventral striatum, the M-M model cannot simulate dorsal striatal responses that rise concavely. Based on current neurotransmission principles and experimental FSCV data, we developed a novel, quantitative, neurobiological framework to interpret DA responses that assumes DA release decreases exponentially during stimulation and continues post-stimulation at a diminishing rate. Our model also incorporates dynamic M-M kinetics to describe DA reuptake as a process of decreasing reuptake efficiency. We demonstrate that this quantitative, neurobiological model is an extension of the traditional M-M model that can simulate heterogeneous regional DA responses following manipulation of stimulation duration, frequency, and DA pharmacology. The proposed model can advance our interpretive framework for future in vivo FSCV studies examining regional DA kinetics and their alteration by disease and DA pharmacology. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. Regulatory Technology Development Plan - Sodium Fast Reactor: Mechanistic Source Term – Trial Calculation

    Energy Technology Data Exchange (ETDEWEB)

    Grabaskas, David [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Bucknor, Matthew [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Jerden, James [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Brunett, Acacia J. [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Denman, Matthew [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Nuclear Engineering Division; Clark, Andrew [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Nuclear Engineering Division; Denning, Richard S. [Consultant, Columbus, OH (United States)

    2016-10-01

    The potential release of radioactive material during a plant incident, referred to as the source term, is a vital design metric and will be a major focus of advanced reactor licensing. The U.S. Nuclear Regulatory Commission has stated an expectation for advanced reactor vendors to present a mechanistic assessment of the potential source term in their license applications. The mechanistic source term presents an opportunity for vendors to realistically assess the radiological consequences of an incident and may allow reduced emergency planning zones and smaller plant sites. However, the development of a mechanistic source term for advanced reactors is not without challenges, as there are often numerous phenomena impacting the transportation and retention of radionuclides. This project sought to evaluate U.S. capabilities regarding the mechanistic assessment of radionuclide release from core damage incidents at metal fueled, pool-type sodium fast reactors (SFRs). The purpose of the analysis was to identify, and prioritize, any gaps regarding computational tools or data necessary for the modeling of radionuclide transport and retention phenomena. To accomplish this task, a parallel-path analysis approach was utilized, as shown below. One path, led by Argonne and Sandia National Laboratories, sought to perform a mechanistic source term assessment using available codes, data, and models, with the goal to identify gaps in the current knowledge base. The second path, performed by an independent contractor, performed sensitivity analyses to determine the importance of particular radionuclides and transport phenomena in regards to offsite consequences. The results of the two pathways were combined to prioritize gaps in current capabilities.

  4. Note: Development of fast heating inert gas annealing apparatus operated at atmospheric pressure

    Science.gov (United States)

    Das, S. C.; Majumdar, A.; Shripathi, T.; Hippler, R.

    2012-04-01

    Here, we report the development of a simple, small, fast heating, and portable, homemade, inert gas (Ar) atmospheric annealing setup. Instead of using a conventional heating element, a commercial soldering rod having an encapsulated fast heating heater is used here. The sample holder is made of a block of stainless steel. It takes 200 s to reach 700 °C, and 10 min to cool down. The probability of oxidation or surface contamination has been examined by means of x ray photoelectron spectroscopy of virgin Cu sample after annealing at 600 °C. In addition, we compare the annealing of a hydrogenated carbon nitride film (HCNx) in both a conventional vacuum and our newly developed ambient Ar atmosphere setup.

  5. A Fast Ellipsoid Model for Asteroids Inverted From Lightcurves

    CERN Document Server

    Lu, Xiaoping; You, Zhong

    2012-01-01

    The research about asteroids attracts more and more attention recently, especially focusing on their physical structures, such as the spin axis, the rotation period and the shape. The long distance between Earth observers and asteroids makes it impossible to get the shape and other parameters of asteroids directly with the exception of the NEAs (Near Earth Asteroids) and others passed by some spacecrafts. Generally photometric measurement is still the main way to obtain the research data for asteroids now, i.e. the lightcurves recording the brightness and positions of asteroids. Supposing that the shape of the asteroid is a triaxial ellipsoid with a stable spinning status, a new method is present in this article to reconstruct the shape models of asteroids from the lightcurves, with the other physical parameters together. By applying a special curvature function, the method calculates the brightness integration on a unit sphere and Lebedev Quadrature is employed for the discretization. At last the method sear...

  6. Effects of Nuclear Energy on Sustainable Development and Energy Security: Sodium-Cooled Fast Reactor Case

    OpenAIRE

    Sungjoo Lee; Byungun Yoon; Juneseuk Shin

    2016-01-01

    We propose a stepwise method of selecting appropriate indicators to measure effects of a specific nuclear energy option on sustainable development and energy security, and also to compare an energy option with another. Focusing on the sodium-cooled fast reactor, one of the highlighted Generation IV reactors, we measure and compare its effects with the standard pressurized water reactor-based nuclear power, and then with coal power. Collecting 36 indicators, five experts select seven key indic...

  7. How Product Development Can Be Improved in Fast Fashion Industry: An Italian Case

    OpenAIRE

    d’Avolio, Elisa; Bandinelli, Romeo; Rinaldi, Rinaldo

    2015-01-01

    Part 13: Cyberphysical and Smart Systems; International audience; The fast fashion industry is characterized by a complex supply chain configuration, lots of players and an important critical success factor: time to market. In order to ensure the compliance to the fashion collection timing, the entire Product Development process has to be optimized through the analysis of both the flows of material and information. The authors have personally been involved in an in-depth case study, aiming to...

  8. Fast development and improved performance of environmental immunoassays using phage borne peptides

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez-Techera, A.; Umpierrez, M.; Carlomagno, M.; Gonzalez-Sapienza, G.

    2009-07-01

    The need for simple and high-throughput analysis of small molecules such as pesticides, drugs and persistent chemicals in the environment is rapidly growing. Immunoassays, which are simple, robust and fast techniques, are widely used for this purpose in a broad range of applications. Their simplicity and low cost make them suitable for large scale studies, particularly in the developing world were the lack of resources always works as a major obstacle for environmental studies. (Author)

  9. Five Basic Opinions to Promote Fast and Healthy Development of the Capital Market

    Institute of Scientific and Technical Information of China (English)

    Shang Fulin

    2007-01-01

    @@ Shang Fulin, chairman of China Securities Regulatory Commission, wrote and released an article titled "Report on China Economy" and pointed out that the country has reached the target of completing reform on the longtime problem about the different privileges of the interest groups of state shares, corporate shares and common shares. Under this new arrangement, he put forward five basic opinions to promote healthy and fast development of China capital market.

  10. A Fast Variational Approach for Learning Markov Random Field Language Models

    Science.gov (United States)

    2015-01-01

    our class of models. Learning undirected graphical models is challenging because of the global nor- malization constant, or partition function. We...503–528, 1989. Marcus, Mitchell P, Marcinkiewicz, Mary Ann, and San- torini, Beatrice. Building a large annotated corpus of english : The penn treebank...A Fast Variational Approach for Learning Markov Random Field Language Models Yacine Jernite JERNITE@CS.NYU.EDU CIMS, New York University, 251 Mercer

  11. Fast and Parallel Spectral Transform Algorithms for Global Shallow Water Models

    Science.gov (United States)

    Jakob, Ruediger

    1993-01-01

    This dissertation examines spectral transform algorithms for the solution of the shallow water equations on the sphere and studies their implementation and performance on shared memory vector multiprocessors. Beginning with the standard spectral transform algorithm in vorticity divergence form and its implementation in the Fortran based parallel programming language Force, two modifications are researched. First, the transforms and matrices associated with the meridional derivatives of the associated Legendre functions are replaced by corresponding operations with the spherical harmonic coefficients. Second, based on the fast Fourier transform and the fast multipole method, a lower complexity algorithm is derived that uses fast transformations between Legendre and interior Fourier nodes, fast surface spherical truncation and a fast spherical Helmholtz solver. The first modification is fully implemented, and comparative performance data are obtained for varying resolution and number of processes, showing a significant storage saving and slightly reduced execution time on a Cray Y -MP 8/864. The important performance parameters for the spectral transform algorithm and its implementation on vector multiprocessors are determined and validated with the measured performance data. The second modification is described at the algorithmic level, but only the novel fast surface spherical truncation algorithm is implemented. This new multipole algorithm has lower complexity than the standard algorithm, and requires asymptotically only order N ^2log N operations per time step for a grid with order N^2 points. Because the global shallow water equations are similar to the horizontal dynamical component of general circulation models, the results can be applied to spectral transform numerical weather prediction and climate models. In general, the derived algorithms may speed up the solution of time dependent partial differential equations in spherical geometry. A performance model

  12. Modeling of thermo-mechanical and irradiation behavior of mixed oxide fuel for sodium fast reactors

    Science.gov (United States)

    Karahan, Aydın; Buongiorno, Jacopo

    2010-01-01

    An engineering code to model the irradiation behavior of UO2-PuO2 mixed oxide fuel pins in sodium-cooled fast reactors was developed. The code was named fuel engineering and structural analysis tool (FEAST-OXIDE). FEAST-OXIDE has several modules working in coupled form with an explicit numerical algorithm. These modules describe: (1) fission gas release and swelling, (2) fuel chemistry and restructuring, (3) temperature distribution, (4) fuel-clad chemical interaction and (5) fuel-clad mechanical analysis. Given the fuel pin geometry, composition and irradiation history, FEAST-OXIDE can analyze fuel and cladding thermo-mechanical behavior at both steady-state and design-basis transient scenarios. The code was written in FORTRAN-90 program language. The mechanical analysis module implements the LIFE algorithm. Fission gas release and swelling behavior is described by the OGRES and NEFIG models. However, the original OGRES model has been extended to include the effects of joint oxide gain (JOG) formation on fission gas release and swelling. A detailed fuel chemistry model has been included to describe the cesium radial migration and JOG formation, oxygen and plutonium radial distribution and the axial migration of cesium. The fuel restructuring model includes the effects of as-fabricated porosity migration, irradiation-induced fuel densification, grain growth, hot pressing and fuel cracking and relocation. Finally, a kinetics model is included to predict the clad wastage formation. FEAST-OXIDE predictions have been compared to the available FFTF, EBR-II and JOYO databases, as well as the LIFE-4 code predictions. The agreement was found to be satisfactory for steady-state and slow-ramp over-power accidents.

  13. Theoretical models for the regulation of DNA replication in fast-growing bacteria

    Science.gov (United States)

    Creutziger, Martin; Schmidt, Mischa; Lenz, Peter

    2012-09-01

    Growing in always changing environments, Escherichia coli cells are challenged by the task to coordinate growth and division. In particular, adaption of their growth program to the surrounding medium has to guarantee that the daughter cells obtain fully replicated chromosomes. Replication is therefore to be initiated at the right time, which is particularly challenging in media that support fast growth. Here, the mother cell initiates replication not only for the daughter but also for the granddaughter cells. This is possible only if replication occurs from several replication forks that all need to be correctly initiated. Despite considerable efforts during the last 40 years, regulation of this process is still unknown. Part of the difficulty arises from the fact that many details of the relevant molecular processes are not known. Here, we develop a novel theoretical strategy for dealing with this general problem: instead of analyzing a single model, we introduce a wide variety of 128 different models that make different assumptions about the unknown processes. By comparing the predictions of these models we are able to identify the key quantities that allow the experimental discrimination of the different models. Analysis of these quantities yields that out of the 128 models 94 are not consistent with available experimental data. From the remaining 34 models we are able to conclude that mass growth and DNA replication need either to be truly coupled, by coupling DNA replication initiation to the event of cell division, or to the amount of accumulated mass. Finally, we make suggestions for experiments to further reduce the number of possible regulation scenarios.

  14. On modelling the Fast Radio Burst population and event rate predictions

    Science.gov (United States)

    Bera, Apurba; Bhattacharyya, Siddhartha; Bharadwaj, Somnath; Bhat, N. D. Ramesh; Chengalur, Jayaram N.

    2016-04-01

    Assuming that Fast Radio Bursts (FRBs) are of extragalactic origin, we have developed a formalism to predict the FRB detection rate and the redshift distribution of the detected events for a telescope with given parameters. We have adopted FRB 110220, for which the emitted pulse energy is estimated to be E0 = 5.4 × 1033 J, as the reference event. The formalism requires us to assume models for (a) pulse broadening due to scattering in the ionized intergalactic medium - we consider two different models for this, (b) the frequency spectrum of the emitted pulse - we consider a power-law model Eν ∝ ν-α with -5 ≤ α ≤ 5, and (c) the comoving number density of the FRB occurrence rate n(E, wi, z) - we ignore the z dependence and assume a fixed intrinsic pulse width wi = 1 ms for all the FRBs. The distribution of the emitted pulse energy E is modelled through (a) a delta function where all the FRBs have the same energy E = E0, and (b) a Schechter luminosity function where the energies have a spread around E0. The models are all normalized using the four FRBs detected by Thornton et al. Our model predictions for the Parkes telescope are all consistent with the inferred redshift distribution of the 14 FRBs detected there to date. We also find that scattering places an upper limit on the redshift of the FRBs detectable by a given telescope; for the Parkes telescope, this is z ˜ 2. Considering the upcoming Ooty Wide Field Array, we predict an FRB detection rate of ˜0.01 to ˜103 d-1.

  15. Implementation of rooftop reciculation parameterization into the QUIC fast response urban wind model

    Energy Technology Data Exchange (ETDEWEB)

    Bagal, N. (Nilesh); Singh, B. (Balwinder); Pardyjak, E. R. (Eric R.); Brown, M. J. (Michael J.)

    2004-01-01

    The QUIC (Quick Urban & Industrial Complex) dispersion modeling system has been developed to provide high-resolution wind and concentration fields in cities. The fast response 3D urban wind model QUIC-URB explicitly solves for the flow field around buildings using a suite of empirical parameterizations and mass conservation. This procedure is based on the work of Rockle (1990). The current Rockle (1990) model does not capture the rooftop recirculation region associated with flow separation from the leading edge of an isolated building. According to Banks et al. (2001), there are two forms of separation depending on the incident wind angle. For an incident wind angle within 20{sup o} of perpendicular to the front face of the building, 'bubble separation' occurs in which cylindrical vortices whose axis are orthogonal to the flow are generated along the rooftop surface (see Fig. 1). For a 'corner wind' flow or incident wind angle of 30{sup o} to 70{sup o} of perpendicular to the front face of the building, 'conical' or 'delta wing' vortices form along the roof surface (Fig. 3). In this work, a model for rooftop recirculation is implemented into the QUIC- URB model for the two incident wind angle regimes described above. The parameterizations for the length and height of the recirculation region are from Wilson (1979) for the case of flow perpendicular or near perpendicular to the building and from Banks et al. (2000) for the case of off-angle flow. In this paper, we describe the rooftop algorithms and show how the model results are improved through comparisons to experimental data (Snyder and Lawson 1994).

  16. CFD Modeling of Sodium-Oxide Deposition in Sodium-Cooled Fast Reactor Compact Heat Exchangers

    Energy Technology Data Exchange (ETDEWEB)

    Tatli, Emre; Ferroni, Paolo; Mazzoccoli, Jason

    2015-09-02

    The possible use of compact heat exchangers (HXs) in sodium-cooled fast reactors (SFR) employing a Brayton cycle is promising due to their high power density and resulting small volume in comparison with conventional shell-and-tube HXs. However, the small diameter of their channels makes them more susceptible to plugging due to Na2O deposition during accident conditions. Although cold traps are designed to reduce oxygen impurity levels in the sodium coolant, their failure, in conjunction with accidental air ingress into the sodium boundary, could result in coolant oxygen levels that are above the saturation limit in the cooler parts of the HX channels. This can result in Na2O crystallization and the formation of solid deposits on cooled channel surfaces, limiting or even blocking coolant flow. The development of analysis tools capable of modeling the formation of these deposits in the presence of sodium flow will allow designers of SFRs to properly size the HX channels so that, in the scenario mentioned above, the reactor operator has sufficient time to detect and react to the affected HX. Until now, analytical methodologies to predict the formation of these deposits have been developed, but never implemented in a high-fidelity computational tool suited to modern reactor design techniques. This paper summarizes the challenges and the current status in the development of a Computational Fluid Dynamics (CFD) methodology to predict deposit formation, with particular emphasis on sensitivity studies on some parameters affecting deposition.

  17. An Integrated Dynamic Model of Ocean Mining System and Fast Simulation of Its Longitudinal Reciprocating Motion

    Institute of Scientific and Technical Information of China (English)

    DAI Yu; LIU Shao-jun

    2013-01-01

    An integrated dynamic model of China's deep ocean mining system is developed and the fast simulation analysis of its longitudinal reciprocating motion operation processes is achieved.The seafloor tracked miner is built as a three-dimensional single-body model with six-degree-of-freedom.The track-terrain interaction is modeled by partitioning the track-terrain interface into a certain number of mesh elements with three mutually perpendicular forces,including the normal force,the longitudinal shear force and the lateral shear force,acting on the center point of each mesh element.The hydrodynamic force of the miner is considered and applied.By considering the operational safety and collection efficiency,two new mining paths for the miner on the seafloor are proposed,which can be simulated with the established single-body dynamic model of the miner.The pipeline subsystem is built as a three-dimensional multi-body discrete element model,which is divided into rigid elements linked by flexible connectors.The flexible connector without mass is represented by six spring-damper elements.The external hydrodynamic forces of the ocean current from the longitudinal and lateral directions are both considered and modeled based on the Morison formula and applied to the mass center of each corresponding discrete rigid element.The mining ship is simplified and represented by a general kinematic point,whose heave motion induced by the ocean waves and the longitudinal and lateral towing motions are considered and applied.By integrating the single-body dynamic model of the miner and the multi-body discrete element dynamic model of the pipeline,and defining the kinematic equations of the mining ship,the integrated dynamic model of the total deep ocean mining system is formed.The longitudinal reciprocating motion operation modes of the total mining system,which combine the active straight-line and turning motions of the miner and the ship,and the passive towed motions of the pipeline

  18. Challenges of Remote Sensing and Spatial Information Education and Technology Transfer in a Fast Developing Industry

    Science.gov (United States)

    Tsai, F.; Chen, L.-C.

    2014-04-01

    During the past decade, Taiwan has experienced an unusual and fast growing in the industry of mapping, remote sensing, spatial information and related markets. A successful space program and dozens of advanced airborne and ground-based remote sensing instruments as well as mobile mapping systems have been implemented and put into operation to support the vast demands of geospatial data acquisition. Moreover, in addition to the government agencies and research institutes, there are also tens of companies in the private sector providing geo-spatial data and services. However, the fast developing industry is also posing a great challenge to the education sector in Taiwan, especially the higher education for geo-spatial information. Facing this fast developing industry, the demands of skilled professionals and new technologies in order to address diversified needs are indubitably high. Consequently, while delighting in the expanding and prospering benefitted from the fast growing industry, how to fulfill these demands has become a challenge for the remote sensing and spatial information disciplines in the higher education institutes in Taiwan. This paper provides a brief insight into the status of the remote sensing and spatial information industry in Taiwan as well as the challenges of the education and technology transfer to support the increasing demands and to ensure the continuous development of the industry. In addition to the report of the current status of the remote sensing and spatial information related courses and programs in the colleges and universities, current and potential threatening issues and possible resolutions are also discussed in different points of view.

  19. Serial Coronary Imaging of Early Atherosclerosis Development in Fast-Food-Fed Diabetic and Nondiabetic Swine

    Directory of Open Access Journals (Sweden)

    Nienke S. van Ditzhuijzen, MSc

    2016-10-01

    Full Text Available Patients with diabetes mellitus (DM are at increased risk for atherosclerosis-related events compared to non-DM (NDM patients. With an expected worldwide epidemic of DM, early detection of anatomic and functional coronary atherosclerotic changes is gaining attention. To improve our understanding of early atherosclerosis development, we studied a swine model that gradually developed coronary atherosclerosis. Interestingly, optical coherence tomography, near-infrared spectroscopy (NIRS, vascular function, and histology demonstrated no differences between development of early atherosclerosis in fast-food-fed (FF DM swine and that in FF-NDM swine. Coronary computed tomography angiography did not detect early atherosclerosis, but optical coherence tomography and near-infrared spectroscopy demonstrated coronary atherosclerosis development in FF-DM and FF-NDM swine.

  20. Comparison study of fast responses in confined plasmas with diffusivity models

    Energy Technology Data Exchange (ETDEWEB)

    Iwasaki, Takuya [Interdisciplinary Graduate School of Engineering Sciences, Kyushu University, Kasuga, Fukuoka (Japan); Itoh, Sanae-I.; Yagi, Masatoshi [Kyushu Univ., Fukuoka (Japan). Research Inst. for Applied Mechanics; Itoh, Kimitaka [National Inst. for Fusion Science, Toki, Gifu (Japan)

    2000-03-01

    An equation which includes the non-local effect in the heat flux is introduced to study the transient transport phenomena. A non-local heat flux, which is expressed in terms of the integral equation, is superimposed on the conventional form of the heat flux. This model is applied to describe the fast responses in the transition from Low confinement mode (L-mode) to High confinement mode (H-mode) and in the heating power switching. Examples of diffusivity models are chosen, i.e., constant, Bohm and Rebut-Lallia-Watkins (RLW) model and the comparison study is done. A small reaction of non-local component in the heat flux is found to be very effective in reducing the response time. Independent of the diffusivity models, the fast transient transport in the heat pulse propagation is reproduced based on this non-local model. (author)

  1. EFDA Task TW6-TPDS-DIADEV deliverable 2: ITER fast ion collective scattering development of diagnostic components and techniques

    Energy Technology Data Exchange (ETDEWEB)

    Michelsen, S.; Bindslev, H.; Korsholm, S.B.; Leipold, F.; Meo, F.; Michelsen, P.K.; Nielsen, A.H.; Tsakadze, E.

    2009-12-15

    In 2003 the Risoe CTS group finished a feasibility study and a conceptual design of an ITER fast ion collective Thomson scattering system. The purpose of the CTS diagnostic is to measure the distribution function of fast ions in the plasma with particular interest in fusion alphas. The feasibility study demonstrated that the only system, which can fully meet the ITER measurement requirements for confined fusion alphas, is a 60 GHz system. The study showed that by using two powerful microwave sources (gyrotrons) of this frequency both on the low field side, and two antenna systems, one on the low field side and one on the high field side, it is possible to resolve the distribution function of fast ions both for perpendicular andvparallel velocities with good spatial and temporal resolution. The present workvconcerned a continuation of this work, and the following tasks were performed. 1) Optimisation of the design, considering the scattering geometries, variations in plasma profiles, magnetic equilibria etc. 2) Development of numerical codes for determination of the geometry of the antenna system on the high field side, including shapes and positions of mirrors and receiver horns. 3) A model experiment was set up in order to test and support the theoretical and numerical results. From the design studies various R and D issues critical to the viability of the CTS diagnostic on ITER were identified; the most urgent ones are addressed in the presented R and D tasks. (author)

  2. Modeling of natural circulation for the inherent safety analysis of sodium cooled fast reactors

    Directory of Open Access Journals (Sweden)

    A.S. Bochkarev

    2016-12-01

    Full Text Available The paper discusses a set of developed integrated one-dimensional models of thermal-hydraulic processes that contribute to the removal of decay heat in a BN-type reactor. The assumptions and constraints involved in one-dimensional equations of unsteady natural convection in closed circuits have been analyzed. It has been shown that the calculated values of the primary circuit sodium temperature and flow rate in conditions with a loss of heat sink and with a forced circulation of the primary coolant are in a reasonable agreement with the results of a benchmark experiment in the PHENIX reactor. The model makes it possible to assess the effects general thermophysical and geometrical parameters and the selected technology have on the efficiency of passive heat removal by the natural coolant convection in the reactor tank and in the emergency heat removal system's intermediate circuit and by the heat transfer through the reactor vessel. The model is a part of an integrated algorithm used to assess the inherent safety level of advanced fast neutron reactors and is intended primarily to develop, at the early conceptual design stage, the recommendations and requirements with respect to the reactor equipment parameters leading to an increase in the reactor inherent safety. The model will be used to identify the set of quantitative thermal-hydraulic criteria that have an effect on the dynamics of emergency transients leading to a potential loss of integrity by the reactor safety barriers, and to formulate such limits for the defined criteria as would cause, if observed, the requirement for the safety barrier integrity to be met under any combination of the accident initiating events.

  3. Fast pyrolysis in a novel wire-mesh reactor: decomposition of pine wood and model compounds

    NARCIS (Netherlands)

    Hoekstra, E.; Swaaij, van W.P.M.; Kersten, S.R.A.; Hogendoorn, J.A.

    2012-01-01

    In fast pyrolysis, biomass decomposition processes are followed by vapor phase reactions. Experimental results were obtained in a unique wire-mesh reactor using pine wood, KCl impregnated pine wood and several model compounds (cellulose, xylan, lignin, levoglucosan, glucose). The wire-mesh reactor w

  4. Fast and accurate exercise policies for Bermudan swaptions in the LIBOR market model

    NARCIS (Netherlands)

    Karlsson, P.K.; Jain, S.; Oosterlee, C.W.

    2016-01-01

    This paper describes an American Monte Carlo approach for obtaining fast and accurate exercise policies for pricing of callable LIBOR Exotics (e.g., Bermudan swaptions) in the LIBOR market model using the Stochastic Grid Bundling Method (SGBM). SGBM is a bundling and regression based Monte Carlo met

  5. Development of fast and high throughput tomography using CMOS image detector at SPring-8

    Science.gov (United States)

    Uesugi, Kentaro; Hoshino, Masato; Takeuchi, Akihisa; Suzuki, Yoshio; Yagi, Naoto

    2012-10-01

    A fast micro-tomography system and a high throughput micro-tomography system using state-of-the-art Complementary Metal Oxide Semiconductor (CMOS) imaging devices have been developed at SPring-8. Those systems adopt simple projection type tomography using synchrotron radiation X-ray. The fast micro-tomography system achieves a scan time around 2 s with 1000 projections, which is 15 times faster than previously developed system at SPring-8. The CMOS camera for fast tomography has 64 Giga Byte on-board memory, therefore, the obtained images must be transferred to a PC at the appropriate timing. A melting process of snow at room temperature was imaged every 30 s as a demonstration of the system. The high throughput tomography system adopts a scientific CMOS (sCMOS) camera with a low noise and high quantum efficiency. The system achieves a scan time around 5 minutes which is three times faster than before. The images quality of the system has been compared to the existing system with Charge-Coupled Device (CCD) camera. The results have shown the advantage of the new sCMOS camera.

  6. Modeling and Validation of Sodium Plugging for Heat Exchangers in Sodium-cooled Fast Reactor Systems

    Energy Technology Data Exchange (ETDEWEB)

    Ferroni, Paolo [Westinghouse Electric Company LLC, Cranberry Township, PA (United States). Global Technology Development; Tatli, Emre [Westinghouse Electric Company LLC, Cranberry Township, PA (United States); Czerniak, Luke [Westinghouse Electric Company LLC, Cranberry Township, PA (United States); Sienicki, James J. [Argonne National Lab. (ANL), Argonne, IL (United States); Chien, Hual-Te [Argonne National Lab. (ANL), Argonne, IL (United States); Yoichi, Momozaki [Argonne National Lab. (ANL), Argonne, IL (United States); Bakhtiari, Sasan [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-06-29

    The project “Modeling and Validation of Sodium Plugging for Heat Exchangers in Sodium-cooled Fast Reactor Systems” was conducted jointly by Westinghouse Electric Company (Westinghouse) and Argonne National Laboratory (ANL), over the period October 1, 2013- March 31, 2016. The project’s motivation was the need to provide designers of Sodium Fast Reactors (SFRs) with a validated, state-of-the-art computational tool for the prediction of sodium oxide (Na2O) deposition in small-diameter sodium heat exchanger (HX) channels, such as those in the diffusion bonded HXs proposed for SFRs coupled with a supercritical CO2 (sCO2) Brayton cycle power conversion system. In SFRs, Na2O deposition can potentially occur following accidental air ingress in the intermediate heat transport system (IHTS) sodium and simultaneous failure of the IHTS sodium cold trap. In this scenario, oxygen can travel through the IHTS loop and reach the coldest regions, represented by the cold end of the sodium channels of the HXs, where Na2O precipitation may initiate and continue. In addition to deteriorating HX heat transfer and pressure drop performance, Na2O deposition can lead to channel plugging especially when the size of the sodium channels is small, which is the case for diffusion bonded HXs whose sodium channel hydraulic diameter is generally below 5 mm. Sodium oxide melts at a high temperature well above the sodium melting temperature such that removal of a solid plug such as through dissolution by pure sodium could take a lengthy time. The Sodium Plugging Phenomena Loop (SPPL) was developed at ANL, prior to this project, for investigating Na2O deposition phenomena within sodium channels that are prototypical of the diffusion bonded HX channels envisioned for SFR-sCO2 systems. In this project, a Computational Fluid Dynamic (CFD) model capable of simulating the thermal-hydraulics of the SPPL test

  7. Ultra Fast Tomography: New Developments for 4D Studies in Material Science

    Science.gov (United States)

    Lhuissier, Pierre; Scheel, Mario; Di Michiel, Marco; Boller, Elodie; Adrien, Jerome; Maire, Eric; Salvo, Luc; Blandin, Jean-Jacques; Suery, Michel

    X-ray tomography has become a widely used 3D characterization technique in materials science using either laboratory tomographs or large X-ray facilities. The two main improvements in the last decade are the decrease of the spatial resolution down to tens of nanometers and also the decrease in acquisition time of a complete scan down to 1 second with 2 µm spatial resolution. The aim of this presentation is to focus on the second point. We will present the technical problems arising due to ultra fast acquisition (development of specific sample environment) and its application in material science. We will show, that thanks to ultra fast tomography, it is now possible to investigate material science problems in 4D (crack propagation in metals and high temperature deformation).

  8. Development of a fast traveling-wave beam chopper for the SNS project

    Energy Technology Data Exchange (ETDEWEB)

    Kurennoy, S.S.; Power, J.F.

    1998-12-31

    High current and stringent restrictions on beam losses, below 1 nA/m, in the designed linac for the Spallation Neutron Source (SNS) require clean and fast--with the rise time from 2% to 98% less than 2.5 ns--beam chopping in its front end, at the beam energy 2.5 MeV. The development of new traveling-wave deflecting current structures based on meander lines is discussed. Three-dimensional time-domain computer simulations with MAFIA are used to study transient effects in the chopper and to optimize current structure design. Two options for the fast pulsed voltage generator--based on FETs and vacuum tubes--are considered, and their advantages and shortcomings for the SNS chopper are discussed.

  9. Effects of Nuclear Energy on Sustainable Development and Energy Security: Sodium-Cooled Fast Reactor Case

    Directory of Open Access Journals (Sweden)

    Sungjoo Lee

    2016-09-01

    Full Text Available We propose a stepwise method of selecting appropriate indicators to measure effects of a specific nuclear energy option on sustainable development and energy security, and also to compare an energy option with another. Focusing on the sodium-cooled fast reactor, one of the highlighted Generation IV reactors, we measure and compare its effects with the standard pressurized water reactor-based nuclear power, and then with coal power. Collecting 36 indicators, five experts select seven key indicators to meet data availability, nuclear energy relevancy, comparability among energy options, and fit with Korean energy policy objectives. The results show that sodium-cooled fast reactors is a better alternative than existing nuclear power as well as coal electricity generation across social, economic and environmental dimensions. Our method makes comparison between energy alternatives easier, thereby clarifying consequences of different energy policy decisions.

  10. Application of objective provision tree to development of standard review plan for sodium-cooled fast reactor nuclear design

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Moo-Hoon; Suh, Namduk; Choi, Yongwon; Shin, Andong [Korea Institute of Nuclear Safety, Daejon (Korea, Republic of)

    2016-06-15

    A systematic methodology was developed for the standard review plan for sodium-cooled fast reactor nuclear design. The process is first to develop an objective provision tree of sodium-cooled fast reactor for the reactivity control safety function. The provision tree is generally developed by designer to confirm whether the design satisfies the defense-in-depth concept. Then applicability of the current standard review plan of nuclear design for light water reactor to sodium-cooled fast reactor was evaluated and complemented by the developed objective provision tree.

  11. Development of Pool-type Sodium-cooled Fast Reactor System Analysis Code%池式钠冷快堆系统分析程序开发

    Institute of Scientific and Technical Information of China (English)

    王晋; 张东辉; 胡文军

    2016-01-01

    针对池式钠冷快堆的特点,在对快堆系统的水力模型、热工模型和中子动力学模型进行详细分类和建模的基础上,利用 FORTRAN95语言开发了可用于池式钠冷快堆事故分析的系统分析程序(FASYS程序)。以中国实验快堆为计算对象对FASYS程序模型进行了初步验证,所获得的结果和试验值与其他系统程序计算值符合良好,证明了所开发的系统分析程序的正确性。%According to the characteristics of pool‐type sodium‐cooled fast reactor ,and with the fast reactor hydraulic model , thermal model and neutron kinetics model thoroughly classified and developed ,a fast reactor system analysis code (FASYS code) was developed by FORTRAN95 language for pool‐type sodium‐cooled fast reactor acci‐dent analysis .Transient conditions in CEFR were calculated with FASYS code and the results were used for code validation .The calculation results are consistent with the test data and other fast reactor system analysis code results , and the correctness of the FASYS code is proved .

  12. Plant development models

    NARCIS (Netherlands)

    Chuine, I.; Garcia de Cortazar-Atauri, I.; Kramer, K.; Hänninen, H.

    2013-01-01

    In this chapter we provide a brief overview of plant phenology modeling, focusing on mechanistic phenological models. After a brief history of plant phenology modeling, we present the different models which have been described in the literature so far and highlight the main differences between them,

  13. Liquid–Liquid Equilibrium Measurements for Model Systems Related to Catalytic Fast Pyrolysis of Biomass

    Energy Technology Data Exchange (ETDEWEB)

    Jasperson, Louis V.; McDougal, Rubin J.; Diky, Vladimir; Paulechka, Eugene; Chirico, Robert D.; Kroenlein, Kenneth; Iisa, Kristiina; Dutta, Abhijit

    2017-01-12

    We report liquid-liquid mutual solubilities for binary aqueous mixtures involving 2-, 3-, and 4-ethylphenol, 2-, 3-, and 4-methoxyphenol, benzofuran, and 1H-indene for the temperature range (300 < T/K < 360). Measurements in the water-rich phase for (2-ethylphenol + water) were extended to T = 440 K to facilitate comparison with literature values. Liquid-liquid equilibrium tie-line determinations were made for four ternary systems involving (water + toluene) mixed with a third component; phenol, 3-ethylphenol, 4-methoxyphenol, or 2,4-dimethylphenol. Literature values at higher temperatures are available for the three (ethylphenol + water) systems, and, in general, good agreement is seen. The ternary system (water + toluene + phenol) has been studied previously with inconsistent results reported in the literature, and one report is shown to be anomalous. All systems are modeled with the predictive methods NIST-Modified-UNIFAC and NIST-COSMO-SAC, with generally good success in the temperature range of interest (300 < T/K < 360). This work is part of a larger project on the testing and development of predictive phase equilibrium models for compound types occurring in catalytic fast pyrolysis of biomass, and background information for the larger project is provided.

  14. Flow Modeling in Pelton Turbines by an Accurate Eulerian and a Fast Lagrangian Evaluation Method

    Directory of Open Access Journals (Sweden)

    A. Panagiotopoulos

    2015-01-01

    Full Text Available The recent development of CFD has allowed the flow modeling in impulse hydro turbines that includes complex phenomena like free surface flow, multifluid interaction, and unsteady, time dependent flow. Some commercial and open-source CFD codes, which implement Eulerian methods, have been validated against experimental results showing satisfactory accuracy. Nevertheless, further improvement of accuracy is still a challenge, while the computational cost is very high and unaffordable for multiparametric design optimization of the turbine’s runner. In the present work a CFD Eulerian approach is applied at first, in order to simulate the flow in the runner of a Pelton turbine model installed at the laboratory. Then, a particulate method, the Fast Lagrangian Simulation (FLS, is used for the same case, which is much faster and hence potentially suitable for numerical design optimization, providing that it can achieve adequate accuracy. The results of both methods for various turbine operation conditions, as also for modified runner and bucket designs, are presented and discussed in the paper. In all examined cases the FLS method shows very good accuracy in predicting the hydraulic efficiency of the runner, although the computed flow evolution and the torque curve exhibit some systematic differences from the Eulerian results.

  15. Assessing a brand equity model for fast moving consumer goods in cosmetic and hygiene industry

    Directory of Open Access Journals (Sweden)

    Alireza Karbasivar

    2014-11-01

    Full Text Available This paper presents an empirical investigation to study the effects of ten factors on brand equity. The study provides an assessment using a brand equity model for fast moving consumer goods in cosmetic and hygiene industry. The study has accomplished among people who purchase goods in six major cities of Iran based on an adapted questionnaire originally developed by Aaker (1992a [Aaker, D. A. (1992a. The value of brand equity. Journal of Business Strategy, 13(4, 27-32.]. Cronbach alpha has been calculated as 0.88, which is well above the minimum acceptable level of 0.7. In addition, Kaiser-Meyer-Olkin Measure of Sampling adequacy and Bartlett's test of Sphericity approximation Chi-Square are 0.878, 276628 with Sig. = 0.000, respectively. The proposed study of this paper uses structural equation modeling to test different hypotheses of the survey. The Root Mean Square Error of Approximation (RMSEA, Comparative Fit Index (CFI and Chi-Square/df are 0.067, 0.840 and 4.244 and they are within desirable levels. While the effects of seven factors on brand equity have been confirmed. However, the survey does not confirm the effects of perceived value, advertisement effectiveness and advertisement to brand on brand equity. In our survey, brand loyalty maintains the highest positive impact followed by having updated brand, trust to brand, perceived quality to brand, brand awareness, intensity of supply and perception to brand.

  16. Modeling and Analysis of the Role of Fast-Response Energy Storage in the Smart Grid

    CERN Document Server

    Su, Han-I

    2011-01-01

    The large short time-scale variability of renewable energy resources presents significant challenges to the reliable operation of power systems. This variability can be mitigated by deploying fast-ramping generators. However, these generators are costly to operate and produce environmentally harmful emissions. Fast-response energy storage devices, such as batteries and flywheels, provide an environmentally friendly alternative, but are expensive and have limited capacity. To study the environmental benefits of storage, we introduce a slotted-time dynamic residual dc power flow model with the prediction error of the difference between the generation (including renewables) and the load as input and the fast-ramping generation and the storage (charging/discharging) operation as the control variables used to ensure that the demand is satisfied (as much as possible) in each time slot. We assume the input prediction error sequence to be i.i.d. zero-mean random variables. The optimal power flow problem is then formu...

  17. Fast 3D spine reconstruction of postoperative patients using a multilevel statistical model.

    Science.gov (United States)

    Lecron, Fabian; Boisvert, Jonathan; Mahmoudi, Saïd; Labelle, Hubert; Benjelloun, Mohammed

    2012-01-01

    Severe cases of spinal deformities such as scoliosis are usually treated by a surgery where instrumentation (hooks, screws and rods) is installed to the spine to correct deformities. Even if the purpose is to obtain a normal spine curve, the result is often straighter than normal. In this paper, we propose a fast statistical reconstruction algorithm based on a general model which can deal with such instrumented spines. To this end, we present the concept of multilevel statistical model where the data are decomposed into a within-group and a between-group component. The reconstruction procedure is formulated as a second-order cone program which can be solved very fast (few tenths of a second). Reconstruction errors were evaluated on real patient data and results showed that multilevel modeling allows better 3D reconstruction than classical models.

  18. Fast and accurate calculation of dilute quantum gas using Uehling-Uhlenbeck model equation

    Science.gov (United States)

    Yano, Ryosuke

    2017-02-01

    The Uehling-Uhlenbeck (U-U) model equation is studied for the fast and accurate calculation of a dilute quantum gas. In particular, the direct simulation Monte Carlo (DSMC) method is used to solve the U-U model equation. DSMC analysis based on the U-U model equation is expected to enable the thermalization to be accurately obtained using a small number of sample particles and the dilute quantum gas dynamics to be calculated in a practical time. Finally, the applicability of DSMC analysis based on the U-U model equation to the fast and accurate calculation of a dilute quantum gas is confirmed by calculating the viscosity coefficient of a Bose gas on the basis of the Green-Kubo expression and the shock layer of a dilute Bose gas around a cylinder.

  19. Data assimilation in slow-fast systems using homogenized climate models

    CERN Document Server

    Mitchell, Lewis

    2011-01-01

    A deterministic multiscale toy model is studied in which a chaotic fast subsystem triggers rare transitions between slow regimes, akin to weather or climate regimes. Using homogenization techniques, a reduced stochastic parametrization model is derived for the slow dynamics. The reliability of this reduced climate model in reproducing the statistics of the slow dynamics of the full deterministic model for finite values of the time scale separation is numerically established. The statistics however is sensitive to uncertainties in the parameters of the stochastic model. It is investigated whether the stochastic climate model can be beneficial as a forecast model in an ensemble data assimilation setting, in particular in the realistic setting when observations are only available for the slow variables. The main result is that reduced stochastic models can indeed improve the analysis skill, when used as forecast models instead of the perfect full deterministic model. The stochastic climate model is far superior ...

  20. Fast numerical methods for mixed-integer nonlinear model-predictive control

    CERN Document Server

    Kirches, Christian

    2011-01-01

    Christian Kirches develops a fast numerical algorithm of wide applicability that efficiently solves mixed-integer nonlinear optimal control problems. He uses convexification and relaxation techniques to obtain computationally tractable reformulations for which feasibility and optimality certificates can be given even after discretization and rounding.

  1. OBLIMAP 2.0: a fast climate model-ice sheet model coupler including online embeddable mapping routines

    Science.gov (United States)

    Reerink, Thomas J.; van de Berg, Willem Jan; van de Wal, Roderik S. W.

    2016-11-01

    This paper accompanies the second OBLIMAP open-source release. The package is developed to map climate fields between a general circulation model (GCM) and an ice sheet model (ISM) in both directions by using optimal aligned oblique projections, which minimize distortions. The curvature of the surfaces of the GCM and ISM grid differ, both grids may be irregularly spaced and the ratio of the grids is allowed to differ largely. OBLIMAP's stand-alone version is able to map data sets that differ in various aspects on the same ISM grid. Each grid may either coincide with the surface of a sphere, an ellipsoid or a flat plane, while the grid types might differ. Re-projection of, for example, ISM data sets is also facilitated. This is demonstrated by relevant applications concerning the major ice caps. As the stand-alone version also applies to the reverse mapping direction, it can be used as an offline coupler. Furthermore, OBLIMAP 2.0 is an embeddable GCM-ISM coupler, suited for high-frequency online coupled experiments. A new fast scan method is presented for structured grids as an alternative for the former time-consuming grid search strategy, realising a performance gain of several orders of magnitude and enabling the mapping of high-resolution data sets with a much larger number of grid nodes. Further, a highly flexible masked mapping option is added. The limitation of the fast scan method with respect to unstructured and adaptive grids is discussed together with a possible future parallel Message Passing Interface (MPI) implementation.

  2. Development of a Fast Fluid-Structure Coupling Technique for Wind Turbine Computations

    DEFF Research Database (Denmark)

    Sessarego, Matias; Ramos García, Néstor; Shen, Wen Zhong

    2015-01-01

    Fluid-structure interaction simulations are routinely used in the wind energy industry to evaluate the aerodynamic and structural dynamic performance of wind turbines. Most aero-elastic codes in modern times implement a blade element momentum technique to model the rotor aerodynamics and a modal......, multi-body, or finite-element approach to model the turbine structural dynamics. The present paper describes a novel fluid-structure coupling technique which combines a threedimensional viscous-inviscid solver for horizontal-axis wind-turbine aerodynamics, called MIRAS, and the structural dynamics model...... used in the aero-elastic code FLEX5. The new code, MIRASFLEX, in general shows good agreement with the standard aero-elastic codes FLEX5 and FAST for various test cases. The structural model in MIRAS-FLEX acts to reduce the aerodynamic load computed by MIRAS, particularly near the tip and at high wind...

  3. Multiscale stochastic finite element method on random field modeling of geotechnical problems- a fast computing procedure

    Institute of Scientific and Technical Information of China (English)

    Xi F. XU

    2015-01-01

    The Green-function-based multiscale stochastic finite element method (MSFEM) has been formulated based on the stochastic variational principle. In this study a fast computing procedure based on the MSFEM is developed to solve random field geotechnical problems with a typical coefficient of variance less than 1. A unique fast computing advantage of the procedure enables computation performed only on those locations of interest, therefore saving a lot of computation. The numerical example on soil settlement shows that the procedure achieves significant computing efficiency compared with Monte Carlo method.

  4. Linearized model for the hydrodynamic stability investigation of molten fuel jets into the coolant of a Liquid Metal Fast Breeder Reactor (LMFBR)

    Science.gov (United States)

    Hartel, K.

    1986-02-01

    The hydrodynamic stability of liquid jets in a liquid continuum, both characterized by low viscosity was analyzed. A linearized mathematical model was developed. This model enables the length necessary for fragmentation of a vertical, symmetric jet of molten fuel by hydraulic forces in the coolant of a liquid metal fast breeder reactor to be evaluated. On the basis of this model the FRAG code for numerical calculation of the hydrodynamic fragmentation mechanism was developed.

  5. Program development: role of the clinical nurse specialist in implementing a fast-track postanesthesia care unit.

    Science.gov (United States)

    Harrington, Linda

    2005-01-01

    Advanced practice nurses are involved in many aspects of program development as part of their roles. This can involve such things as developing programs for staff and family education, organizing system-wide quality assurance programs, or implementing new care programs. One unique aspect of the advanced practice nurse's role is the ability to serve as a change agent and implement new models of care. Although all advanced practice nurses can be involved in program development, the role of the Clinical Nurse Specialist lends itself to devoting dedicated services for implementing programmatic change in the clinical setting. This article describes the role of the Clinical Nurse Specialist in implementing an evidence-based, fast-track postanesthesia care unit.

  6. Monte Carlo modeling of Lead-Cooled Fast Reactor in adiabatic equilibrium state

    Energy Technology Data Exchange (ETDEWEB)

    Stanisz, Przemysław, E-mail: pstanisz@agh.edu.pl; Oettingen, Mikołaj, E-mail: moettin@agh.edu.pl; Cetnar, Jerzy, E-mail: cetnar@mail.ftj.agh.edu.pl

    2016-05-15

    Graphical abstract: - Highlights: • We present the Monte Carlo modeling of the LFR in the adiabatic equilibrium state. • We assess the adiabatic equilibrium fuel composition using the MCB code. • We define the self-adjusting process of breeding gain by the control rod operation. • The designed LFR can work in the adiabatic cycle with zero fuel breeding. - Abstract: Nuclear power would appear to be the only energy source able to satisfy the global energy demand while also achieving a significant reduction of greenhouse gas emissions. Moreover, it can provide a stable and secure source of electricity, and plays an important role in many European countries. However, nuclear power generation from its birth has been doomed by the legacy of radioactive nuclear waste. In addition, the looming decrease in the available resources of fissile U235 may influence the future sustainability of nuclear energy. The integrated solution to both problems is not trivial, and postulates the introduction of a closed-fuel cycle strategy based on breeder reactors. The perfect choice of a novel reactor system fulfilling both requirements is the Lead-Cooled Fast Reactor operating in the adiabatic equilibrium state. In such a state, the reactor converts depleted or natural uranium into plutonium while consuming any self-generated minor actinides and transferring only fission products as waste. We present the preliminary design of a Lead-Cooled Fast Reactor operating in the adiabatic equilibrium state with the Monte Carlo Continuous Energy Burnup Code – MCB. As a reference reactor model we apply the core design developed initially under the framework of the European Lead-cooled SYstem (ELSY) project and refined in the follow-up Lead-cooled European Advanced DEmonstration Reactor (LEADER) project. The major objective of the study is to show to what extent the constraints of the adiabatic cycle are maintained and to indicate the phase space for further improvements. The analysis

  7. Development of objective provision trees for Sodium-Cooled Fast Reactor Defense-in-depth evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Huichang [TUEV Rheinland Korea Ltd., Seoul (Korea, Republic of); Suh, Namduk [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2013-05-15

    KALIMER is one of sodium-cooled fast reactor and being developed by Korea Atomic Energy Research Institute (KAERI), was developed and suggested in this paper. Developed OPT is for the defense-in-depth level 3, core heat removal safety function. Using OPT method, the evaluation of defense-in-depth implementation for the design features of KALIMER reactors were tried in this study. To utilize the design information of KALIMER, challenges in OPTs which are under development in this study, were identified based on the system physical boundaries. This approach make the identification of possible and postulated challenges much clear and this will be a benefit to further identification of provisions in KALIMER design. OPTs for other levels of defense-in-depth and other safety functions are under development.

  8. Alternative business models for establishing fast-charging stations - Part 2; Alternative forretningsmodeller for etablering av hurtigladestasjoner - Del 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-11-01

    This section of the report describes and evaluates potential business models for fast-charging stations. Business models are developed on the basis of market development for electric vehicles and electric vehicle usage patterns analyzed in Part 1 of the project. This report describes a series of models in both the early and maturity stage, where we have distinguished between different user segments and payment models. With the estimated trends in the car fleet and charger use, the prerequisites for profitable quick charging in the downtown area are good, while, due to high construction contribution, you must have a relatively high proportion of subscriptions and a high charge rate to obtain adequate finances in the corridor points.(auth)

  9. Development of polymer-bound fast-dissolving metformin buccal film with disintegrants

    Science.gov (United States)

    Haque, Shaikh Ershadul; Sheela, Angappan

    2015-01-01

    Fast-dissolving drug-delivery systems are considered advantageous over the existing conventional oral dosage forms like tablets, capsules, and syrups for being patient friendly. Buccal films are one such system responsible for systemic drug delivery at the desired site of action by avoiding hepatic first-pass metabolism. Metformin hydrochloride (Met), an antidiabetic drug, has poor bioavailability due to its high solubility and low permeability. The purpose of the study reported here was to develop a polymer-bound fast-dissolving buccal film of metformin to exploit these unique properties. In the study, metformin fast-dissolving films were prepared by the solvent-casting method using chitosan, a bioadhesive polymer. Further, starch, sodium starch glycolate, and microcrystalline cellulose were the disintegrants added to different ratios, forming various formulations (F1 to F7). The buccal films were evaluated for various parameters like weight variation, thickness, folding endurance, surface pH, content uniformity, tensile strength, and percentage of elongation. The films were also subjected to in vitro dissolution study, and the disintegration time was found to be less than 30 minutes for all formulations, which was attributed to the effect of disintegrants. Formulation F6 showed 92.2% drug release within 6 minutes due to the combined effect of sodium starch glycolate and microcrystalline cellulose. PMID:26491321

  10. Retrieving ice cloud properties by using a fast infrared radiative transfer model

    Science.gov (United States)

    Wang, C.; Yang, P.; Heidinger, A. K.; Platnick, S. E.; Baum, B. A.

    2010-12-01

    A new fast infrared radiative transfer (RT) model based on pre-computed look-up tables (LUTs) including the LUTs for emissivity function and cloud effective temperature is proposed. This model can be applied to the simulation of upward radiance (or brightness temperature) at 8.5, 11.0 and 12.0 μm at the top of the atmosphere (TOA) under cloudy-sky conditions. Optical depths of Atmospheric layers resulting from gaseous absorption are derived from the correlated-K distribution (CKD) method. The cloud reflection and transmission functions are computed from the discrete ordinates radiative transfer model (DISORT). In addition to the LUTs of reflection and transmission functions of cloud in traditional RT models, the LUTs of emissivity and effective temperature are also included to improve the accuracy. Generally speaking, for an atmosphere containing a single ice cloud layer with small optical thickness (i.e., less than 5.0), the brightness temperature differences (BTDs) between the fast model and DISORT results are approximately less than 0.1K, whereas the BTDs are less than 0.02K when the ice cloud optical thickness is larger than 5.0. Moreover, with the fast RT model, cloud optical and microphysical properties of ice clouds are retrieved from MODIS and CALIPSO observations and the MERRA reanalysis data. The present retrievals are compared with the MODIS operational cloud products (MYD06).

  11. Sodium fast reactor gaps analysis of computer codes and models for accident analysis and reactor safety.

    Energy Technology Data Exchange (ETDEWEB)

    Carbajo, Juan (Oak Ridge National Laboratory, Oak Ridge, TN); Jeong, Hae-Yong (Korea Atomic Energy Research Institute, Daejeon, Korea); Wigeland, Roald (Idaho National Laboratory, Idaho Falls, ID); Corradini, Michael (University of Wisconsin, Madison, WI); Schmidt, Rodney Cannon; Thomas, Justin (Argonne National Laboratory, Argonne, IL); Wei, Tom (Argonne National Laboratory, Argonne, IL); Sofu, Tanju (Argonne National Laboratory, Argonne, IL); Ludewig, Hans (Brookhaven National Laboratory, Upton, NY); Tobita, Yoshiharu (Japan Atomic Energy Agency, Ibaraki-ken, Japan); Ohshima, Hiroyuki (Japan Atomic Energy Agency, Ibaraki-ken, Japan); Serre, Frederic (Centre d' %C3%94etudes nucl%C3%94eaires de Cadarache %3CU%2B2013%3E CEA, France)

    2011-06-01

    This report summarizes the results of an expert-opinion elicitation activity designed to qualitatively assess the status and capabilities of currently available computer codes and models for accident analysis and reactor safety calculations of advanced sodium fast reactors, and identify important gaps. The twelve-member panel consisted of representatives from five U.S. National Laboratories (SNL, ANL, INL, ORNL, and BNL), the University of Wisconsin, the KAERI, the JAEA, and the CEA. The major portion of this elicitation activity occurred during a two-day meeting held on Aug. 10-11, 2010 at Argonne National Laboratory. There were two primary objectives of this work: (1) Identify computer codes currently available for SFR accident analysis and reactor safety calculations; and (2) Assess the status and capability of current US computer codes to adequately model the required accident scenarios and associated phenomena, and identify important gaps. During the review, panel members identified over 60 computer codes that are currently available in the international community to perform different aspects of SFR safety analysis for various event scenarios and accident categories. A brief description of each of these codes together with references (when available) is provided. An adaptation of the Predictive Capability Maturity Model (PCMM) for computational modeling and simulation is described for use in this work. The panel's assessment of the available US codes is presented in the form of nine tables, organized into groups of three for each of three risk categories considered: anticipated operational occurrences (AOOs), design basis accidents (DBA), and beyond design basis accidents (BDBA). A set of summary conclusions are drawn from the results obtained. At the highest level, the panel judged that current US code capabilities are adequate for licensing given reasonable margins, but expressed concern that US code development activities had stagnated and that the

  12. Fast unilateral isometric knee extension torque development and bilateral jump height.

    Science.gov (United States)

    de Ruiter, Cornelis J; Van Leeuwen, Daniel; Heijblom, Arjan; Bobbert, Maarten F; de Haan, Arnold

    2006-10-01

    We hypothesized that the initial rate (first 40 ms) of unilateral knee extensor torque development during a maximally fast isometric contraction would depend on the subjects' ability for fast neural activation and that it would predict bilateral jumping performance. Nine males (21.8 +/- 0.9 yr, means +/- SD) performed unilateral fast isometric knee extensions (120 degrees knee angle) without countermovement on a dynamometer and bilateral squat jumps (SJ) and countermovement jumps (CMJ) starting from 90 and 120 degrees knee angles (full extension = 180 degrees ). The dynamometer contractions started either from full relaxation or from an isometric pre-tension (15% maximal isometric torque, Tmax). Torque time integral for the first 40 ms after torque onset (TTI-40, normalized to Tmax) and averaged normalized rectified knee extensor EMG for 40 ms before fast torque onset (EMG-40) were used to quantify initial torque rise and voluntary muscle activation. TTI-40 without pre-tension (range: 0.02-0.19% Tmax per second) was significantly lower than TTI-40 with pre-tension, and both were significantly (r = 0.81 and 0.80) related to EMG-40. During jumping, similar significant positive relations were found between jump height and knee extensor EMG during the first 100 ms of the rise in ground reaction force. There also were significant positive linear relations between dynamometer TTI-40 and jump height (r = 0.75 (SJ 90), 0.84 (SJ 120), 0.76 (CMJ 90), and 0.86 (CMJ 120)) but not between dynamometer Tmax and jump height (-0.16 < r < 0.02). One-legged TTI-40 to a large extent explained the variation in jump height. The ability to produce a high efferent neural drive before muscle contraction seemed to dominate performance in both the simple single-joint isometric task and the complex multijoint dynamic task.

  13. ModelOMatic: fast and automated model selection between RY, nucleotide, amino acid, and codon substitution models.

    Science.gov (United States)

    Whelan, Simon; Allen, James E; Blackburne, Benjamin P; Talavera, David

    2015-01-01

    Molecular phylogenetics is a powerful tool for inferring both the process and pattern of evolution from genomic sequence data. Statistical approaches, such as maximum likelihood and Bayesian inference, are now established as the preferred methods of inference. The choice of models that a researcher uses for inference is of critical importance, and there are established methods for model selection conditioned on a particular type of data, such as nucleotides, amino acids, or codons. A major limitation of existing model selection approaches is that they can only compare models acting upon a single type of data. Here, we extend model selection to allow comparisons between models describing different types of data by introducing the idea of adapter functions, which project aggregated models onto the originally observed sequence data. These projections are implemented in the program ModelOMatic and used to perform model selection on 3722 families from the PANDIT database, 68 genes from an arthropod phylogenomic data set, and 248 genes from a vertebrate phylogenomic data set. For the PANDIT and arthropod data, we find that amino acid models are selected for the overwhelming majority of alignments; with progressively smaller numbers of alignments selecting codon and nucleotide models, and no families selecting RY-based models. In contrast, nearly all alignments from the vertebrate data set select codon-based models. The sequence divergence, the number of sequences, and the degree of selection acting upon the protein sequences may contribute to explaining this variation in model selection. Our ModelOMatic program is fast, with most families from PANDIT taking fewer than 150 s to complete, and should therefore be easily incorporated into existing phylogenetic pipelines. ModelOMatic is available at https://code.google.com/p/modelomatic/.

  14. Computational fluid dynamics modelling of biomass fast pyrolysis in fluidised bed reactors, focusing different kinetic schemes.

    Science.gov (United States)

    Ranganathan, Panneerselvam; Gu, Sai

    2016-08-01

    The present work concerns with CFD modelling of biomass fast pyrolysis in a fluidised bed reactor. Initially, a study was conducted to understand the hydrodynamics of the fluidised bed reactor by investigating the particle density and size, and gas velocity effect. With the basic understanding of hydrodynamics, the study was further extended to investigate the different kinetic schemes for biomass fast pyrolysis process. The Eulerian-Eulerian approach was used to model the complex multiphase flows in the reactor. The yield of the products from the simulation was compared with the experimental data. A good comparison was obtained between the literature results and CFD simulation. It is also found that CFD prediction with the advanced kinetic scheme is better when compared to other schemes. With the confidence obtained from the CFD models, a parametric study was carried out to study the effect of biomass particle type and size and temperature on the yield of the products.

  15. A Mathematical Model of the Liver Circadian Clock Linking Feeding and Fasting Cycles to Clock Function

    Directory of Open Access Journals (Sweden)

    Aurore Woller

    2016-10-01

    Full Text Available To maintain energy homeostasis despite variable energy supply and consumption along the diurnal cycle, the liver relies on a circadian clock synchronized to food timing. Perturbed feeding and fasting cycles have been associated with clock disruption and metabolic diseases; however, the mechanisms are unclear. To address this question, we have constructed a mathematical model of the mammalian circadian clock, incorporating the metabolic sensors SIRT1 and AMPK. The clock response to various temporal patterns of AMPK activation was simulated numerically, mimicking the effects of a normal diet, fasting, and a high-fat diet. The model reproduces the dampened clock gene expression and NAD+ rhythms reported for mice on a high-fat diet and predicts that this effect may be pharmacologically rescued by timed REV-ERB agonist administration. Our model thus identifies altered AMPK signaling as a mechanism leading to clock disruption and its associated metabolic effects and suggests a pharmacological approach to resetting the clock in obesity.

  16. A Mathematical Model of the Liver Circadian Clock Linking Feeding and Fasting Cycles to Clock Function.

    Science.gov (United States)

    Woller, Aurore; Duez, Hélène; Staels, Bart; Lefranc, Marc

    2016-10-18

    To maintain energy homeostasis despite variable energy supply and consumption along the diurnal cycle, the liver relies on a circadian clock synchronized to food timing. Perturbed feeding and fasting cycles have been associated with clock disruption and metabolic diseases; however, the mechanisms are unclear. To address this question, we have constructed a mathematical model of the mammalian circadian clock, incorporating the metabolic sensors SIRT1 and AMPK. The clock response to various temporal patterns of AMPK activation was simulated numerically, mimicking the effects of a normal diet, fasting, and a high-fat diet. The model reproduces the dampened clock gene expression and NAD(+) rhythms reported for mice on a high-fat diet and predicts that this effect may be pharmacologically rescued by timed REV-ERB agonist administration. Our model thus identifies altered AMPK signaling as a mechanism leading to clock disruption and its associated metabolic effects and suggests a pharmacological approach to resetting the clock in obesity.

  17. Epileptogenic actions of GABA and fast oscillations in the developing hippocampus.

    Science.gov (United States)

    Khalilov, Ilgam; Le Van Quyen, Michel; Gozlan, Henri; Ben-Ari, Yehezkel

    2005-12-08

    GABA excites immature neurons and inhibits adult ones, but whether this contributes to seizures in the developing brain is not known. We now report that in the developing, but not the adult, hippocampus, seizures beget seizures only if GABAergic synapses are functional. In the immature hippocampus, seizures generated with functional GABAergic synapses include fast oscillations that are required to transform a naive network to an epileptic one: blocking GABA receptors prevents the long-lasting sequels of seizures. In contrast, in adult neurons, full blockade of GABA(A) receptors generates epileptogenic high-frequency seizures. Therefore, purely glutamatergic seizures are not epileptogenic in the developing hippocampus. We suggest that the density of glutamatergic synapses is not sufficient for epileptogenesis in immature neurons; excitatory GABAergic synapses are required for that purpose. We suggest that the synergistic actions of GABA and NMDA receptors trigger the cascades involved in epileptogenesis in the developing hippocampus.

  18. The Sustainable Development Model

    OpenAIRE

    2012-01-01

    Sustainable development concept approaches quality of life in complexity, as economic, social and environmental issues, promoting the idea of balance between economic development, social equity, efficient utilization and environment conservation.     An essential condition for achieving sustainable development is the right mix of macroeconomic policies coherent, consistent with resources to ensure sustainability of materials and energy used for growth.

  19. Metal Fuel Development and Verification for Prototype Generation IV Sodium-Cooled Fast Reactor

    OpenAIRE

    Chan Bock Lee; Jin Sik Cheon; Sung Ho Kim; Jeong-Yong Park; Hyung-Kook Joo

    2016-01-01

    Metal fuel is being developed for the prototype generation-IV sodium-cooled fast reactor (PGSFR) to be built by 2028. U–Zr fuel is a driver for the initial core of the PGSFR, and U–transuranics (TRU)–Zr fuel will gradually replace U–Zr fuel through its qualification in the PGSFR. Based on the vast worldwide experiences of U–Zr fuel, work on U–Zr fuel is focused on fuel design, fabrication of fuel components, and fuel verification tests. U–TRU–Zr fuel uses TRU recovered through pyroelectrochem...

  20. On Developing a Spectroscopic System for Fast Gas Temperature Measurements in Combustion Environments

    DEFF Research Database (Denmark)

    Evseev, Vadim; Clausen, Sønnik

    2009-01-01

    Fourier Transform Infra Red (FTIR) spectroscopy techniques are known to provide reliable results for gas temperature measurements and can be comparatively easily performed on an industrial scale such as a boiler on a power plant or an exhaust of a ship engine cylinder. However temporal resolution...... is not high enough to trace fast temperature variations which are of great importance for complete combustion diagnostics. To eliminate the above mentioned shortcoming, a new IR spectroscopic-imaging system has been developed at Risø DTU. The schematic of the system is presented. Results on lab and industrial...

  1. Metal fuel development and verification for prototype generation- IV Sodium- Cooled Fast Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Chan Bock; Cheon, Jin Sik; Kim, Sung Ho; Park, Jeong Yong; Joo, Hyung Kook [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    Metal fuel is being developed for the prototype generation-IV sodium-cooled fast reactor (PGSFR) to be built by 2028. U-Zr fuel is a driver for the initial core of the PGSFR, and U -transuranics (TRU)-Zr fuel will gradually replace U-Zr fuel through its qualification in the PGSFR. Based on the vast worldwide experiences of U-Zr fuel, work on U-Zr fuel is focused on fuel design, fabrication of fuel components, and fuel verification tests. U-TRU-Zr fuel uses TRU recovered through pyroelectrochemical processing of spent PWR (pressurized water reactor) fuels, which contains highly radioactive minor actinides and chemically active lanthanide or rare earth elements as carryover impurities. An advanced fuel slug casting system, which can prevent vaporization of volatile elements through a control of the atmospheric pressure of the casting chamber and also deal with chemically active lanthanide elements using protective coatings in the casting crucible, was developed. Fuel cladding of the ferritic-martensitic steel FC92, which has higher mechanical strength at a high temperature than conventional HT9 cladding, was developed and fabricated, and is being irradiated in the fast reactor.

  2. Gas Cooled Fast Reactor Research and Development in the European Union

    Directory of Open Access Journals (Sweden)

    Richard Stainsby

    2009-01-01

    Full Text Available Gas-cooled fast reactor (GFR research is directed towards fulfilling the ambitious goals of Generation IV (Gen IV, that is, to develop a safe, sustainable, reliable, proliferation-resistant and economic nuclear energy system. The research is directed towards developing the GFR as an economic electricity generator, with good safety and sustainability characteristics. Fast reactors maximise the usefulness of uranium resources by breeding plutonium and can contribute to minimising both the quantity and radiotoxicity nuclear waste by actinide transmutation in a closed fuel cycle. Transmutation is particularly effective in the GFR core owing to its inherently hard neutron spectrum. Further, GFR is suitable for hydrogen production and process heat applications through its high core outlet temperature. As such GFR can inherit the non-electricity applications that will be developed for thermal high temperature reactors in a sustainable manner. The Euratom organisation provides a route by which researchers in all European states, and other non-European affiliates, can contribute to the Gen IV GFR system. This paper summarises the achievements of Euratom's research into the GFR system, starting with the 5th Framework programme (FP5 GCFR project in 2000, through FP6 (2005 to 2009 and looking ahead to the proposed activities within the 7th Framework Programme (FP7.

  3. AB TEMPORAL TRIP GENERATION MODELLING FOR PRIMARY ACTIVITIES: A CASE STUDY OF FAST GROWING METROPOLITAN CITY

    Directory of Open Access Journals (Sweden)

    Bhimaji K. Katti

    2015-06-01

    Full Text Available Transportation planning for any city evolves on the basis of complex interplay between urban activity, transport and land use system to result in varied travel patterns. Travel pattern can be defined at micro level to include individual journey departure and arrival time, journey duration and distances to make way for temporal trip generation and distribution from specific area. Trip generation is the first step of four stages of travel forecasting analysis mostly followed all over the world. Traditionally, it is focused on the prediction of aggregate trip generation by a household rather than the choice of individual activity participation. However, spatial and temporal activity domains are equally important in forecasting process and strategic urban transportation planning. The present paper attempts to develop Activity Based (AB Temporal Trip Generation Models (ABTGM for primary activities to cover work and educational trips considering fast growing Surat city of Gujarat, India as study area. Home interview surveys are carried to provide household and socioeconomic characteristics and the activity travel diary information to focus on the activity based tours rather the trips.

  4. RAMSIM: A fast computer model for mean wind flow over hills

    Energy Technology Data Exchange (ETDEWEB)

    Corbett, J-F.

    2007-06-15

    The Riso Atmospheric Mixed Spectral-Integration Model (RAMSIM) is a micro-scale, linear flow model developed to quickly calculate the mean wind flow field over orography. It was designed to bridge the gap between WAsP and similar models that are fast but insufficiently accurate over steep slopes, and non-linear CFD models that are accurate but too computationally expensive for routine use on a PC. RAMSIM is governed by the RANS and E-{epsilon} turbulence closure equations, expressed in non-Cartesian coordinates. A terrain-following coordinate system is created from a simple analytical expression. The equations are linearized by a perturbation expansion about the flat-terrain case. The first-order equations, representing the spatial correction due to the presence of orography, are Fourier-transformed analytically in the two horizontal dimensions. The pressure and horizontal velocity components are eliminated, resulting in a set of four ordinary differential equations (ODEs). RAMSIM is currently implemented and tested in two-dimensional space; a 3D version has been formulated but not yet implemented. In the 2D case, there are only three ODEs, depending on only two non-dimensional parameters. This is exploited by solving the ODEs by Runge-Kutta integration for all useful combinations of these parameters, and storing the results in look-up tables (LUT). The flow field over any given orography is then quickly obtained by interpolating from the LUTs and scaling the value of the flow variables for each wavenumber component of the orography, and returning to real space by inverse Fourier transform. RAMSIM was tested against measurements, as well as other authors' flow models, in four test cases: two laboratory flows over idealized terrain, and two field experiments. RAMSIM calculations generally agree with measurements over upward slopes and hilltops, but overestimate the speed very near the ground at hilltops. RAMSIM appears to have an edge over other linear models

  5. Building on knowledge base of sodium cooled fast spectrum reactors to develop materials technology for fusion reactors

    Science.gov (United States)

    Raj, Baldev; Rao, K. Bhanu Sankara

    2009-04-01

    The alloys 316L(N) and Mod. 9Cr-1Mo steel are the major structural materials for fabrication of structural components in sodium cooled fast reactors (SFRs). Various factors influencing the mechanical behaviour of these alloys and different modes of deformation and failure in SFR systems, their analysis and the simulated tests performed on components for assessment of structural integrity and the applicability of RCC-MR code for the design and validation of components are highlighted. The procedures followed for optimal design of die and punch for the near net shape forming of petals of main vessel of 500 MWe prototype fast breeder reactor (PFBR); the safe temperature and strain rate domains established using dynamic materials model for forming of 316L(N) and 9Cr-1Mo steels components by various industrial processes are illustrated. Weldability problems associated with 316L(N) and Mo. 9Cr-1Mo are briefly discussed. The utilization of artificial neural network models for prediction of creep rupture life and delta-ferrite in austenitic stainless steel welds is described. The usage of non-destructive examination techniques in characterization of deformation, fracture and various microstructural features in SFR materials is briefly discussed. Most of the experience gained on SFR systems could be utilized in developing science and technology for fusion reactors. Summary of the current status of knowledge on various aspects of fission and fusion systems with emphasis on cross fertilization of research is presented.

  6. Experimental Validation of Modelled Fluid Forces in Fast Switching Hydraulic On/Off Valves

    DEFF Research Database (Denmark)

    Nørgård, Christian; Bech, Michael Møller; Roemer, Daniel Beck;

    2015-01-01

    A prototype of a fast switching valve for a digital hydraulic machine has been designed and manufactured. The valve is composed of an annular seat plunger connected with a moving coil actuator as the force producing element. The valve prototype is designed for flow rates of 600 l/min with less than...... 0.5 bar pressure drop, and the models predicts a switching time in the region of a millisecond with a travel length of 3.5 mm using an average power of 250 W. The total machine efficiency when neglecting losses not related to the valves is above 98 %. The objective of this paper is to experimentally...... validate a transient computational fluid dynamics (CFD) model of the fluid forces that oppose the valve plunger when moving rapidly through the surrounding oil during switching. Due to the fast switching of the valve, the fluid forces which oppose plunger movement increases drastically as the plunger...

  7. A Mathematical Model of the Liver Circadian Clock Linking Feeding and Fasting Cycles to Clock Function

    OpenAIRE

    Aurore Woller; Hélène Duez; Bart Staels; Marc Lefranc

    2016-01-01

    To maintain energy homeostasis despite variable energy supply and consumption along the diurnal cycle, the liver relies on a circadian clock synchronized to food timing. Perturbed feeding and fasting cycles have been associated with clock disruption and metabolic diseases; however, the mechanisms are unclear. To address this question, we have constructed a mathematical model of the mammalian circadian clock, incorporating the metabolic sensors SIRT1 and AMPK. The clock response to various tem...

  8. Modeling of fast capillary discharge for collisionally excited soft x-ray lasers: comparison with experiments

    Science.gov (United States)

    Shlyaptsev, Vyacheslav N.; Gerusov, Alexey V.; Vinogradov, Alexander V.; Rocca, Jorge J. G.; Cortazar, O. D.; Tomasel, Fernando G.; Szapiro, Benito T.

    1994-02-01

    In this paper we report results of a model of a fast capillary discharge (FCD) and discuss them in comparison with experiments. The overall good coincidence between theory and experiment and the observation of stable reproducible compression are beneficial properties of FCD which open the possibility for achieving X-ray laser action in a compact discharge device. The required discharge parameters for lasing in different atomic elements have been calculated.

  9. The development of a realistic source term for sodium-cooled fast reactors : assessment of current status and future needs.

    Energy Technology Data Exchange (ETDEWEB)

    LaChance, Jeffrey L.; Phillips, Jesse; Parma, Edward J., Jr.; Olivier, Tara Jean; Middleton, Bobby D.

    2011-06-01

    Sodium-cooled fast reactors (SFRs) continue to be proposed and designed throughout the United States and the world. Although the number of SFRs actually operating has declined substantially since the 1980s, a significant interest in advancing these types of reactor systems remains. Of the many issues associated with the development and deployment of SFRs, one of high regulatory importance is the source term to be used in the siting of the reactor. A substantial amount of modeling and experimental work has been performed over the past four decades on accident analysis, sodium coolant behavior, and radionuclide release for SFRs. The objective of this report is to aid in determining the gaps and issues related to the development of a realistic, mechanistically derived source term for SFRs. This report will allow the reader to become familiar with the severe accident source term concept and gain a broad understanding of the current status of the models and experimental work. Further, this report will allow insight into future work, in terms of both model development and experimental validation, which is necessary in order to develop a realistic source term for SFRs.

  10. Fast Parameters Estimation in Medication Efficacy Assessment Model for Heart Failure Treatment

    Directory of Open Access Journals (Sweden)

    Yinzi Ren

    2012-01-01

    Full Text Available Introduction. Heart failure (HF is a common and potentially fatal condition. Cardiovascular research has focused on medical therapy for HF. Theoretical modelling could enable simulation and evaluation of the effectiveness of medications. Furthermore, the models could also help predict patients’ cardiac response to the treatment which will be valuable for clinical decision-making. Methods. This study presents a fast parameters estimation algorithm for constructing a cardiovascular model for medicine evaluation. The outcome of HF treatment is assessed by hemodynamic parameters and a comprehensive index furnished by the model. Angiotensin-converting enzyme inhibitors (ACEIs were used as a model drug in this study. Results. Our simulation results showed different treatment responses to enalapril and lisinopril, which are both ACEI drugs. A dose-effect was also observed in the model simulation. Conclusions. Our results agreed well with the findings from clinical trials and previous literature, suggesting the validity of the model.

  11. On a mean field game optimal control approach modeling fast exit scenarios in human crowds

    KAUST Repository

    Burger, Martin

    2013-12-01

    The understanding of fast exit and evacuation situations in crowd motion research has received a lot of scientific interest in the last decades. Security issues in larger facilities, like shopping malls, sports centers, or festivals necessitate a better understanding of the major driving forces in crowd dynamics. In this paper we present an optimal control approach modeling fast exit scenarios in pedestrian crowds. The model is formulated in the framework of mean field games and based on a parabolic optimal control problem. We consider the case of a large human crowd trying to exit a room as fast as possible. The motion of every pedestrian is determined by minimizing a cost functional, which depends on his/her position and velocity, the overall density of people, and the time to exit. This microscopic setup leads in a mean-field formulation to a nonlinear macroscopic optimal control problem, which raises challenging questions for the analysis and numerical simulations.We discuss different aspects of the mathematical modeling and illustrate them with various computational results. ©2013 IEEE.

  12. An Optimal Control Modification to Model-Reference Adaptive Control for Fast Adaptation

    Science.gov (United States)

    Nguyen, Nhan T.; Krishnakumar, Kalmanje; Boskovic, Jovan

    2008-01-01

    This paper presents a method that can achieve fast adaptation for a class of model-reference adaptive control. It is well-known that standard model-reference adaptive control exhibits high-gain control behaviors when a large adaptive gain is used to achieve fast adaptation in order to reduce tracking error rapidly. High gain control creates high-frequency oscillations that can excite unmodeled dynamics and can lead to instability. The fast adaptation approach is based on the minimization of the squares of the tracking error, which is formulated as an optimal control problem. The necessary condition of optimality is used to derive an adaptive law using the gradient method. This adaptive law is shown to result in uniform boundedness of the tracking error by means of the Lyapunov s direct method. Furthermore, this adaptive law allows a large adaptive gain to be used without causing undesired high-gain control effects. The method is shown to be more robust than standard model-reference adaptive control. Simulations demonstrate the effectiveness of the proposed method.

  13. A non-traditional model of the metabolic syndrome: the adaptive significance of insulin resistance in fasting-adapted seals

    Directory of Open Access Journals (Sweden)

    Dorian S Houser

    2013-11-01

    Full Text Available Insulin resistance in modern society is perceived as a pathological consequence of excess energy consumption and reduced physical activity. Its presence in relation to the development of cardiovascular risk factors has been termed the metabolic syndrome, which produces increased mortality and morbidity and which is rapidly increasing in human populations. Ironically, insulin resistance likely evolved to assist animals during food shortages by increasing the availability of endogenous lipid for catabolism while protecting protein from use in gluconeogenesis and eventual oxidation. Some species that incorporate fasting as a predictable component of their life history demonstrate physiological traits similar to the metabolic syndrome during prolonged fasts. One such species is the northern elephant seal (Mirounga angustirostris, which fasts from food and water for periods of up to three months. During this time, ~90% of the seals metabolic demands are met through fat oxidation and circulating non-esterified fatty acids are high (0.7-3.2 mM. All life history stages of elephant seal studied to date demonstrate insulin resistance and fasting hyperglycemia as well as variations in hormones and adipocytokines that reflect the metabolic syndrome to some degree. Elephant seals demonstrate some intriguing adaptations with the potential for medical advancement; for example, ketosis is negligible despite significant and prolonged fatty acid oxidation and investigation of this feature might provide insight into the treatment of diabetic ketoacidosis. The parallels to the metabolic syndrome are likely reflected to varying degrees in other marine mammals, most of which evolved on diets high in lipid and protein content but essentially devoid of carbohydrate. Utilization of these natural models of insulin resistance may further our understanding of the pathophysiology of the metabolic syndrome in humans and better assist the development of preventative measures

  14. A coupling of hydrologic and hydraulic models appropriate for the fast floods of the Gardon river basin (France: results and comparisons with others modelling options

    Directory of Open Access Journals (Sweden)

    O. Laganier

    2013-09-01

    Full Text Available Mediterranean catchments are regularly affected by fast and flash floods. Numerous hydrologic models were developed, and allow to reconstruct these floods. However, these approaches often concern average size basins, of some hundreds km2. At more important scales (>1000 km2, a coupling of hydrologic and hydraulic models appears to be an adapted solution. This study analyses the performances of a coupling of models and compares them with those of others modelling strategies. The distributed SCS-LR hydrologic model implemented in the ATHYS modelling platform ( http://www.athys-soft.org , and the MASCARET hydraulic modelling code, based on full Saint-Venant equations, are employed. The coupling is applied to the Gardon river basin (2040 km2, in the southeast of France. The results are satisfactory at the downstream stations. Furthermore, the coupling has few parameters, expecting interesting perspectives for flood forecasting.

  15. Development of the Sodium-cooled Fast Reactor R and D and Technology Monitoring System

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dong Uk; Won, Byung Chool; Kim, Young In; Hahn, Do Hee

    2008-01-15

    This study presents a R and D performance monitoring system that is applicable for managing the generation IV sodium-cooled fast reactor development. The prime goal of this system is to furnish project manager with reliable and accurate information of status of progress, performance and resource allocation, and attain traceability and visibility of project implementation for effective project management. In this study, the work breakdown structure, the related schedule and the expected outputs were established to derive the interfaces between projects and the above parameters was loaded PCs. The R and D performance monitoring system is composed of about 750 R and D activities within 'Development of Basic Key Technologies for Gen IV SFR' project in 2007. The Microsoft Project Professional software was used to monitor the progress, evaluate the results and analyze the resource distribution to activities.

  16. Reovirus FAST Protein Enhances Vesicular Stomatitis Virus Oncolytic Virotherapy in Primary and Metastatic Tumor Models

    Directory of Open Access Journals (Sweden)

    Fabrice Le Boeuf

    2017-09-01

    Full Text Available The reovirus fusion-associated small transmembrane (FAST proteins are the smallest known viral fusogens (∼100–150 amino acids and efficiently induce cell-cell fusion and syncytium formation in multiple cell types. Syncytium formation enhances cell-cell virus transmission and may also induce immunogenic cell death, a form of apoptosis that stimulates immune recognition of tumor cells. These properties suggest that FAST proteins might serve to enhance oncolytic virotherapy. The oncolytic activity of recombinant VSVΔM51 (an interferon-sensitive vesicular stomatitis virus [VSV] mutant encoding the p14 FAST protein (VSV-p14 was compared with a similar construct encoding GFP (VSV-GFP in cell culture and syngeneic BALB/c tumor models. Compared with VSV-GFP, VSV-p14 exhibited increased oncolytic activity against MCF-7 and 4T1 breast cancer spheroids in culture and reduced primary 4T1 breast tumor growth in vivo. VSV-p14 prolonged survival in both primary and metastatic 4T1 breast cancer models, and in a CT26 metastatic colon cancer model. As with VSV-GFP, VSV-p14 preferentially replicated in vivo in tumors and was cleared rapidly from other sites. Furthermore, VSV-p14 increased the numbers of activated splenic CD4, CD8, natural killer (NK, and natural killer T (NKT cells, and increased the number of activated CD4 and CD8 cells in tumors. FAST proteins may therefore provide a multi-pronged approach to improving oncolytic virotherapy via syncytium formation and enhanced immune stimulation.

  17. Econometric models for biohydrogen development.

    Science.gov (United States)

    Lee, Duu-Hwa; Lee, Duu-Jong; Veziroglu, Ayfer

    2011-09-01

    Biohydrogen is considered as an attractive clean energy source due to its high energy content and environmental-friendly conversion. Analyzing various economic scenarios can help decision makers to optimize development strategies for the biohydrogen sector. This study surveys econometric models of biohydrogen development, including input-out models, life-cycle assessment approach, computable general equilibrium models, linear programming models and impact pathway approach. Fundamentals of each model were briefly reviewed to highlight their advantages and disadvantages. The input-output model and the simplified economic input-output life-cycle assessment model proved most suitable for economic analysis of biohydrogen energy development. A sample analysis using input-output model for forecasting biohydrogen development in the United States is given.

  18. Modeling and Validation of Sodium Plugging for Heat Exchangers in Sodium-cooled Fast Reactor Systems

    Energy Technology Data Exchange (ETDEWEB)

    Ferroni, Paolo [Westinghouse Electric Company LLC, Cranberry Township, PA (United States). Global Technology Development; Tatli, Emre [Westinghouse Electric Company LLC, Cranberry Township, PA (United States); Czerniak, Luke [Westinghouse Electric Company LLC, Cranberry Township, PA (United States); Sienicki, James J. [Argonne National Lab. (ANL), Argonne, IL (United States); Chien, Hual-Te [Argonne National Lab. (ANL), Argonne, IL (United States); Yoichi, Momozaki [Argonne National Lab. (ANL), Argonne, IL (United States); Bakhtiari, Sasan [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-06-29

    The project “Modeling and Validation of Sodium Plugging for Heat Exchangers in Sodium-cooled Fast Reactor Systems” was conducted jointly by Westinghouse Electric Company (Westinghouse) and Argonne National Laboratory (ANL), over the period October 1, 2013- March 31, 2016. The project’s motivation was the need to provide designers of Sodium Fast Reactors (SFRs) with a validated, state-of-the-art computational tool for the prediction of sodium oxide (Na2O) deposition in small-diameter sodium heat exchanger (HX) channels, such as those in the diffusion bonded HXs proposed for SFRs coupled with a supercritical CO2 (sCO2) Brayton cycle power conversion system. In SFRs, Na2O deposition can potentially occur following accidental air ingress in the intermediate heat transport system (IHTS) sodium and simultaneous failure of the IHTS sodium cold trap. In this scenario, oxygen can travel through the IHTS loop and reach the coldest regions, represented by the cold end of the sodium channels of the HXs, where Na2O precipitation may initiate and continue. In addition to deteriorating HX heat transfer and pressure drop performance, Na2O deposition can lead to channel plugging especially when the size of the sodium channels is small, which is the case for diffusion bonded HXs whose sodium channel hydraulic diameter is generally below 5 mm. Sodium oxide melts at a high temperature well above the sodium melting temperature such that removal of a solid plug such as through dissolution by pure sodium could take a lengthy time. The Sodium Plugging Phenomena Loop (SPPL) was developed at ANL, prior to this project, for investigating Na2O deposition phenomena within sodium channels that are prototypical of the diffusion bonded HX channels envisioned for SFR-sCO2 systems. In this project, a Computational Fluid Dynamic (CFD) model capable of simulating the thermal-hydraulics of the SPPL test

  19. Educational Game Development Models

    Directory of Open Access Journals (Sweden)

    Mehmet Emin Korkusuz

    2013-12-01

    Full Text Available Recent research on the subject shows that students spend more time on computer games than other activities such as reading book or watching TV. It is possible that this time-consuming activity can become much more effective by educator-game sector cooperation. Which type of game students prefer mostly; how the educational content can be articulated the games without diminishing the playability and enjoyableness of it; and the impact of the competition in the games on process and students are just several titles examined in the studies. This scope presents the types of computer game, qualities of educational games, and educational games designs which are recommended for developing educational games. It also presents a set of knowledge about the importance of educational games in mathematics and physic education, and some studies on this field. In the scope, some strategies, about educational game development process, are recommended educators and software developers in the sector who intend to develop educational games based on the literature.

  20. Modelling fast spreading patterns of airborne infectious diseases using complex networks

    Science.gov (United States)

    Brenner, Frank; Marwan, Norbert; Hoffmann, Peter

    2017-04-01

    The pandemics of SARS (2002/2003) and H1N1 (2009) have impressively shown the potential of epidemic outbreaks of infectious diseases in a world that is strongly connected. Global air travelling established an easy and fast opportunity for pathogens to migrate globally in only a few days. This made epidemiological prediction harder. By understanding this complex development and its link to climate change we can suggest actions to control a part of global human health affairs. In this study we combine the following data components to simulate the outbreak of an airborne infectious disease that is directly transmitted from human to human: em{Global Air Traffic Network (from openflights.org) with information on airports, airport location, direct flight connection, airplane type} em{Global population dataset (from SEDAC, NASA)} em{Susceptible-Infected-Recovered (SIR) compartmental model to simulate disease spreading in the vicinity of airports. A modified Susceptible-Exposed-Infected-Recovered (SEIR) model to analyze the impact of the incubation period.} em{WATCH-Forcing-Data-ERA-Interim (WFDEI) climate data: temperature, specific humidity, surface air pressure, and water vapor pressure} These elements are implemented into a complex network. Nodes inside the network represent airports. Each single node is equipped with its own SIR/SEIR compartmental model with node specific attributes. Edges between those nodes represent direct flight connections that allow infected individuals to move between linked nodes. Therefore the interaction of the set of unique SIR models creates the model dynamics we will analyze. To better figure out the influence on climate change on disease spreading patterns, we focus on Influenza-like-Illnesses (ILI). The transmission rate of ILI has a dependency on climate parameters like humidity and temperature. Even small changes of environmental variables can trigger significant differences in the global outbreak behavior. Apart from the direct

  1. Potential-Field Forward Modeling and Inversion Using 3D Fast Fourier Transforms

    Science.gov (United States)

    Phillips, J. D.; Caratori Tontini, F.; Cocchi, L.

    2008-12-01

    Although 1D and 2D fast Fourier transforms (FFTs) have long been used for the filtering, interpretation, and modeling of potential-field data, 3D FFTs have not enjoyed similar popularity. This may change with the recent discovery (Caratori Tontini et al., in press, JGR) that simple 3D FFT filters can be used to transform distributions of density (or magnetization) within a box-shaped 3D volume into gravity (or magnetic) fields within the same volume. For example, the continuous 3D Fourier transform of the vertical gravity anomaly Δgz(x,y,z) in a volume is related to the 3D Fourier transform of the density ρ(x,y,z) in the volume by ℑ[Δgz] = i4πG(kz/ | k | 2)ℑ[ρ]; | k | ≠0, (1) where G is the gravitational constant, kx, ky, kz are wavenumbers, and | k | 2 = kx2+ ky2+ kz2. (2) Translating (1) into a digital FFT filtering operation requires careful consideration of the periodicity of the density distribution and the gravity field. Nevertheless, (1) provides a highly efficient way to calculate the vertical gravity anomaly of a 3D density distribution within a few minutes. The calculated gravity anomaly can be sampled at random points or on an arbitrary surface using tri-linear interpolation. An equivalent space- domain calculation of the gravity field on an arbitrary surface can take many hours. The inverse relation to (1) does not appear to offer a practical approach for calculating a reliable density distribution from observed gravity data. This is because the data would have to cover a substantial portion of the model volume, and because the transformation is undefined on the plane kz = 0, where both the denominator of the filter kernel and the Fourier transform of the gravity field are identically zero. Numerical experiments show that the density distribution resulting from the power on the plane kz = 0 represents a classic Parker annihilator. This annihilator can be calculated from the density distribution but not from the gravity field, as would be

  2. Fast and accurate prediction of numerical relativity waveforms from binary black hole mergers using surrogate models

    CERN Document Server

    Blackman, Jonathan; Galley, Chad R; Szilagyi, Bela; Scheel, Mark A; Tiglio, Manuel; Hemberger, Daniel A

    2015-01-01

    Simulating a binary black hole coalescence by solving Einstein's equations is computationally expensive, requiring days to months of supercomputing time. In this paper, we construct an accurate and fast-to-evaluate surrogate model for numerical relativity (NR) waveforms from non-spinning binary black hole coalescences with mass ratios from $1$ to $10$ and durations corresponding to about $15$ orbits before merger. Our surrogate, which is built using reduced order modeling techniques, is distinct from traditional modeling efforts. We find that the full multi-mode surrogate model agrees with waveforms generated by NR to within the numerical error of the NR code. In particular, we show that our modeling strategy produces surrogates which can correctly predict NR waveforms that were {\\em not} used for the surrogate's training. For all practical purposes, then, the surrogate waveform model is equivalent to the high-accuracy, large-scale simulation waveform but can be evaluated in a millisecond to a second dependin...

  3. Models for Sustainable Regional Development

    DEFF Research Database (Denmark)

    Rasmussen, Lauge Baungaard

    2008-01-01

    The chapter presents a model for integrated cross-cultural knowledge building and entrepreneurship. In addtion, narrative and numeric simulations methods are suggested to promote a further development and implementation of the model in China.......The chapter presents a model for integrated cross-cultural knowledge building and entrepreneurship. In addtion, narrative and numeric simulations methods are suggested to promote a further development and implementation of the model in China....

  4. Models for Sustainable Regional Development

    DEFF Research Database (Denmark)

    Rasmussen, Lauge Baungaard

    2008-01-01

    The chapter presents a model for integrated cross-cultural knowledge building and entrepreneurship. In addtion, narrative and numeric simulations methods are suggested to promote a further development and implementation of the model in China.......The chapter presents a model for integrated cross-cultural knowledge building and entrepreneurship. In addtion, narrative and numeric simulations methods are suggested to promote a further development and implementation of the model in China....

  5. Thrust Removal Scheme for the FAST-MAC Circulation Control Model Tested in the National Transonic Facility

    Science.gov (United States)

    Chan, David T.; Milholen, William E., II; Jones, Gregory S.; Goodliff, Scott L.

    2014-01-01

    A second wind tunnel test of the FAST-MAC circulation control semi-span model was recently completed in the National Transonic Facility at the NASA Langley Research Center. The model allowed independent control of four circulation control plenums producing a high momentum jet from a blowing slot near the wing trailing edge that was directed over a 15% chord simple-hinged flap. The model was configured for transonic testing of the cruise configuration with 0deg flap deflection to determine the potential for drag reduction with the circulation control blowing. Encouraging results from analysis of wing surface pressures suggested that the circulation control blowing was effective in reducing the transonic drag on the configuration, however this could not be quantified until the thrust generated by the blowing slot was correctly removed from the force and moment balance data. This paper will present the thrust removal methodology used for the FAST-MAC circulation control model and describe the experimental measurements and techniques used to develop the methodology. A discussion on the impact to the force and moment data as a result of removing the thrust from the blowing slot will also be presented for the cruise configuration, where at some Mach and Reynolds number conditions, the thrust-removed corrected data showed that a drag reduction was realized as a consequence of the blowing.

  6. Development of a PYTHON-based emittance calculator at Fermilab Accelerator Science and Technology (FAST) facility

    Science.gov (United States)

    Green, A. T.

    Beam emittance is an important characteristic describing charged particle beams. In linear accelerators (linac), it is critical to characterize the beam phase space parameters and, in particular, to precisely measure transverse beam emittance. The quadrupole scan (quad-scan) is a well-established technique used to characterize transverse beam parameters in four-dimensional phase space, including beam emittance. A computational algorithm with PYTHON scripts has been developed to estimate beam parameters, in particular beam emittance, using the quad-scan technique in the electron linac at the Fermilab Accelerator Science and Technology (FAST) facility. This script has been implemented in conjunction with an automated quad-scan tool (also written in PYTHON) and has decreased the time it takes to perform a single quad-scan from an hour to a few minutes. From the experimental data, the emittance calculator quickly delivers several results including: geometrical and normalized transverse emittance, Courant-Snyder parameters, and plots of the beam size versus quadrupole field strength, among others. This paper will discuss the details of the techniques used, the results from several quad-scans preformed at FAST during the electron injector commissioning, and the PYTHON code used to obtain the results.

  7. Development and characterization of a high sensitivity segmented Fast Neutron Spectrometer (FaNS-2)

    Science.gov (United States)

    Langford, T. J.; Beise, E. J.; Breuer, H.; Heimbach, C. R.; Ji, G.; Nico, J. S.

    2016-01-01

    We present the development of a segmented fast neutron spectrometer (FaNS-2) based upon plastic scintillator and 3He proportional counters. It was designed to measure both the flux and spectrum of fast neutrons in the energy range of few MeV to 1 GeV. FaNS-2 utilizes capture-gated spectroscopy to identify neutron events and reject backgrounds. Neutrons deposit energy in the plastic scintillator before capturing on a 3He nucleus in the proportional counters. Segmentation improves neutron energy reconstruction while the large volume of scintillator increases sensitivity to low neutron fluxes. A main goal of its design is to study comparatively low neutron fluxes, such as cosmogenic neutrons at the Earth's surface, in an underground environment, or from low-activity neutron sources. In this paper, we present details of its design and construction as well as its characterization with a calibrated 252Cf source and monoenergetic neutron fields of 2.5 MeV and 14 MeV. Detected monoenergetic neutron spectra are unfolded using a Singular Value Decomposition method, demonstrating a 5% energy resolution at 14 MeV. Finally, we discuss plans for measuring the surface and underground cosmogenic neutron spectra with FaNS-2.

  8. Development and Characterization of a High Sensitivity Segmented Fast Neutron Spectrometer (FaNS-2)

    CERN Document Server

    Langford, T J; Breuer, H; Heimbach, C R; Ji, G; Nico, J S

    2015-01-01

    We present the development of a segmented fast neutron spectrometer (FaNS-2) based upon plastic scintillator and $^3$He proportional counters. It was designed to measure both the flux and spectrum of fast neutrons in the energy range of few MeV to 1 GeV. FaNS-2 utilizes capture-gated spectroscopy to identify neutron events and reject backgrounds. Neutrons deposit energy in the plastic scintillator before capturing on a $^3$He nucleus in the proportional counters. Segmentation improves neutron energy reconstruction while the large volume of scintillator increases sensitivity to low neutron fluxes. A main goal of its design is to study comparatively low neutron fluxes, such as cosmogenic neutrons at the Earth's surface, in an underground environment, or from low-activity neutron sources. In this paper, we present details of its design and construction as well as its characterization with a calibrated $^{252}$Cf source and monoenergetic neutron fields of 2.5 MeV and 14 MeV. Detected monoenergetic neutron spectra...

  9. The effects of imagery training on fast isometric knee extensor torque development.

    Science.gov (United States)

    de Ruiter, Cornelis J; Hutter, Vana; Icke, Chris; Groen, Bart; Gemmink, Anne; Smilde, Hiltsje; de Haan, Arnold

    2012-01-01

    We hypothesized that imagery training would improve the fast onset of neuromuscular activation and thereby fast knee extensor isometric torque development. Forty young healthy participants, not involved in strength training, were assigned to one of four groups: physical training, imagery training, placebo training or control. The three training groups had three 15 min sessions per week for 4 weeks, with a 90 ° knee angle but were tested also at 120 °. At 90 ° knee angle, maximal torque increased (-8%) similarly in all three training groups. The torque-time integral (contractile impulse) over the first 40 ms after torque onset (TTI40) increased (P training (by -100%), but only at 90 °. This increase was significantly different from the delta values (change pre to post) in the control and placebo groups, whereas delta values in the imagery group were similar to those in the placebo group. The increases in TTI40 following physical training were related (r (2) = 0.81, P training led to a knee angle specific increase of contractile impulse that was significantly different from placebo and controls and that was related to improved onset of neuromuscular activation.

  10. Simulation tools and new developments of the molten salt fast reactor

    Energy Technology Data Exchange (ETDEWEB)

    Merle-Lucotte, E.; Doligez, X.; Heuer, D.; Allibert, M.; Ghetta, V. [LPSC-IN2P3-CNRS / UJF / Grenoble INP, 53 avenue des Martyrs, F-38026 Grenoble Cedex (France)

    2010-07-01

    Starting from the Molten Salt Breeder Reactor project of Oak-Ridge, we have performed parametric studies in terms of safety coefficients, reprocessing requirements and breeding capabilities. In the frame of this major re-evaluation of the molten salt reactor (MSR), we have developed a new concept called Molten Salt Fast Reactor or MSFR, based on the Thorium fuel cycle and a fast neutron spectrum. This concept has been selected for further studies by the MSR steering committee of the Generation IV International Forum in 2009. Our reactor's studies of the MSFR concept rely on numerical simulations making use of the MCNP neutron transport code coupled with a code for materials evolution which resolves the Bateman's equations giving the population of each nucleus inside each part of the reactor at each moment. Because of MSR's fundamental characteristics compared to classical solid-fuelled reactors, the classical Bateman equations have to be modified by adding two terms representing the reprocessing capacities and the fertile or fissile alimentation. We have thus coupled neutronic and reprocessing simulation codes in a numerical tool used to calculate the extraction efficiencies of fission products, their location in the whole system (reactor and reprocessing unit) and radioprotection issues. (authors)

  11. Effects of fast-velocity eccentric resistance training on early and late rate of force development.

    Science.gov (United States)

    Oliveira, Anderson Souza; Corvino, Rogério Bulhões; Caputo, Fabrizio; Aagaard, Per; Denadai, Benedito Sérgio

    2016-01-01

    This study examined whether short-term maximal resistance training employing fast-velocity eccentric knee extensor actions would induce improvements in maximal isometric torque and rate of force development (RFD) at early (100 ms) of rising torque. Twenty healthy men were assigned to two experimental groups: eccentric resistance training (TG) or control (CG). Participants on the TG trained three days a week for a total of eight weeks. Training consisted of maximal unilateral eccentric knee extensors actions performed at 180 °s-1. Maximal isometric knee extensor torque (MVC) and incremental RFD in successive 50 ms time-windows from the onset contraction were analysed in absolute terms (RFDINC) or when normalised relative to MVC (RFDREL). After eight weeks, TG demonstrated increases in MVC (28%), RFDINC (0-50 ms: 30%; 50-100 ms: 31%) and RFDREL (0-50 ms: 29%; 50-100 ms: 32%). Moreover, no changes in the late phase of incremental RFD were observed in TG. No changes were found in the CG. In summary, we have demonstrated, in active individuals, that a short period of resistance training performed with eccentric fast-velocity isokinetic muscle contractions is able to enhance RFDINC and RFDREL obtained at the early phase of rising joint torque.

  12. Are early and late rate of force development differently influenced by fast-velocity resistance training?

    Science.gov (United States)

    de Oliveira, Felipe B D; Rizatto, Guilherme F; Denadai, Benedito S

    2013-07-01

    This study examined the effect of fast-velocity concentric isokinetic resistance training (FV) on the rate of force development (RFD) at early (100 ms) of rising muscle force. Nine men participated in a 6-week resistance training intervention for the lower body, and nine matched subjects participated as controls (CON). During concentric isokinetic (180°s(-1)) knee extension training, subjects were instructed to do each contraction 'as fast and forcefully as possible'. Maximal muscle strength (MVC) and RFD (0-10, 0-20, …, 0-250 ms from the onset of contraction) were measured during maximal voluntary isometric contraction of the knee extensors (KE). There were no significant changes in MVC of KE in both groups after intervention (FV = 314·2 ± 101·1 versus 338·7 ± 88·0 N∙m, P>0·05; CON = 293·3 ± 94·8 versus 280·0 ± 72·2 N∙m, P>0·05). The RFD increased 39-71% at time intervals up to 90 ms from the onset of the contraction (Pforce.

  13. Very fast dissolving acid carboxymethylcellulose-rifampicin matrix: Development and solid-state characterization.

    Science.gov (United States)

    Luciani-Giacobbe, Laura C; Ramírez-Rigo, María V; Garro-Linck, Yamila; Monti, Gustavo A; Manzo, Ruben H; Olivera, María E

    2017-01-01

    One of the main obstacles to the successful treatment of tuberculosis is the poor and variable oral bioavailability of rifampicin (RIF), which is mainly due to its low hydrophilicity and dissolution rate. The aim of this work was to obtain a hydrophilic new material that allows a very fast dissolution rate of RIF and therefore is potentially useful in the development of oral solid dosage forms. The acid form of carboxymethylcellulose (CMC) was co-processed with RIF by solvent impregnation to obtain CMC-RIF powder, which was characterized by polarized optical microscopy, powder x-ray diffraction, DSC-TGA, hot stage microscopy, (13)C and (15)N solid-state NMR and FT-IR spectroscopy. In addition, the CMC-RIF matrices were subjected to water uptake and dissolution studies to assess hydrophilicity and release kinetics. CMC-RIF is a crystalline solid dispersion. Solid-state characterization indicated that no ionic interaction occurred between the components, but RIF crystallized as a zwitterion over the surface of CMC, which drastically increased the hydrophilicity of the solid. The CMC-RIF matrices significantly improved the water uptake of RIF and disintegrated in a very short period immediately releasing RIF. As CMC improves the hydrophilicity and delivery properties of RIF, CMC-RIF is very useful in the design of oral solid dosage forms with very fast dissolution of RIF, either alone or in combination with other antitubercular drugs. Copyright © 2016 Elsevier B.V. All rights reserved.

  14. Fast Tree Search for A Triangular Lattice Model of Protein Folding

    Institute of Scientific and Technical Information of China (English)

    Xiaomei Li; Nengchao Wang

    2004-01-01

    Using a triangular lattice model to study the designability of protein folding, we overcame the parity problem of previous cubic lattice model and enumerated all the sequences and compact structures on a simple two-dimensional triangular lattice model of size 4+5+6+5+4. We used two types of amino acids, hydrophobic and polar, to make up the sequences, and achieved 223+212 different sequences excluding the reverse symmetry sequences. The total string number of distinct compact structures was 219,093, excluding reflection symmetry in the self-avoiding path of length 24 triangular lattice model. Based on this model, we applied a fast search algorithm by constructing a cluster tree. The algorithm decreased the computation by computing the objective energy of non-leaf nodes. The parallel experiments proved that the fast tree search algorithm yielded an exponential speed-up in the model of size 4+5+6+5+4. Designability analysis was performed to understand the search result.

  15. Effect of photoperiod on slow and fast developing individuals in aphidophagous ladybirds, Menochilus sexmaculatus and Propylea dissecta (Coleoptera: Coccinellidae).

    Science.gov (United States)

    Singh, Neha; Mishra, Geetanjali; Omkar

    2016-02-01

    The effects of environmental parameters on insect development have been studied extensively. But the reasons for 2 differential developmental rates within same cohort under varying environmental factors have not been explored. For the purpose, in this study the existence and stability of slow and fast development under 5 photoperiods (i.e., 8L: 16D, 10L : 14D, 12L : 12D, 14L : 10D and 16L : 8D; light and dark hours per day) and its effect on body mass and reproductive attributes in 2 aphidophagous ladybirds, Menochilus sexmaculatus (Fabricius) and Propylea dissecta (Mulsant) was examined on Aphis craccivora Koch at 27 ± 1 °C temperature. A clear bimodal (2 peaks, where the first peak represented the fast developing and the 2nd peak slow developing individuals) pattern of distribution at each photoperiod was found. The proportion of slow and fast developing individuals in a cohort differed with photoperiods. The slow developing individuals were more in numbers at 8L : 16D, in equal numbers at 14L : 10D and in less numbers at 16L: 8D, indicating that the variation in emergence was owing to exogenous cues influenced differential rates of mortality. Slow developing individuals had female biased sex ratio, higher longevity and lower body mass than fast developing individuals. Fast developing females laid higher numbers of eggs with higher egg viability than slow developing females. Study of such variations in development at different photoperiods is helpful to understand its role in the development of insects particularly ladybirds and permits the selection of fast developing bioagents for their use in biocontrol of pest species. © 2014 Institute of Zoology, Chinese Academy of Sciences.

  16. Modeling of the fast organic emissions from a wood-finishing product—Floor wax

    Science.gov (United States)

    Chang, John C. S.; Guo, Zhishi

    Environmental chamber and full-scale residential house tests were conducted to evaluate the fast organic emissions from a wood-finishing product—floor wax. For the environmental chamber tests, a very small amount of (wax was applied to an aluminum plate. It was found that the chamber exit organic concentrations can be estimated by a model with an initial condition of instant organic emissions. The model was applied to the house data to interpret the octane and nonane emissions. Significant sink effects were found in the house that prolonged the elevated octane and nonane concentrations for more than 2 days.

  17. Some Fast Methods for Fitting Some One-parameter Spatial Models

    Directory of Open Access Journals (Sweden)

    R. J. Martin

    2005-01-01

    Full Text Available It is common in geographic modelling to use a one-parameter spatial model to specify the inverse covariance matrix in terms of I-bW, for some known matrix W. Exact Gaussian maximum likelihood estimation of b requires evaluation of the determinant of the covariance matrix. For large data sets, this evaluation of the determinant can be slow and good approximations can be useful. Seventy regional configurations are used to consider some approximations to the determinant of I-bW that are fast to evaluate, and their usefulness is compared.

  18. Lung Motion Model Validation Experiments, Free-Breathing Tissue Densitometry, and Ventilation Mapping using Fast Helical CT Imaging

    Science.gov (United States)

    Dou, Hsiang-Tai

    The uncertainties due to respiratory motion present significant challenges to accurate characterization of cancerous tissues both in terms of imaging and treatment. Currently available clinical lung imaging techniques are subject to inferior image quality and incorrect motion estimation, with consequences that can systematically impact the downstream treatment delivery and outcome. The main objective of this thesis is the development of the techniques of fast helical computed tomography (CT) imaging and deformable image registration for the radiotherapy applications in accurate breathing motion modeling, lung tissue density modeling and ventilation imaging. Fast helical CT scanning was performed on 64-slice CT scanner using the shortest available gantry rotation time and largest pitch value such that scanning of the thorax region amounts to just two seconds, which is less than typical breathing cycle in humans. The scanning was conducted under free breathing condition. Any portion of the lung anatomy undergoing such scanning protocol would be irradiated for only a quarter second, effectively removing any motion induced image artifacts. The resulting CT data were pristine volumetric images that record the lung tissue position and density in a fraction of the breathing cycle. Following our developed protocol, multiple fast helical CT scans were acquired to sample the tissue positions in different breathing states. To measure the tissue displacement, deformable image registration was performed that registers the non-reference images to the reference one. In modeling breathing motion, external breathing surrogate signal was recorded synchronously with the CT image slices. This allowed for the tissue-specific displacement to be modeled as parametrization of the recorded breathing signal using the 5D lung motion model. To assess the accuracy of the motion model in describing tissue position change, the model was used to simulate the original high-pitch helical CT scan

  19. MEANDER-LINE CURRENT STRUCTURE DEVELOPMENT FOR SPALLATION NEUTRON SOURCE FAST CHOPPER

    Energy Technology Data Exchange (ETDEWEB)

    S. KURRENOY; J. POWER

    2000-10-01

    A new current structure for the fast traveling-wave 2.5-MeV beam chopper in the front end of the Spallation Neutron Source (SNS) has been suggested in [1]. The structure is based on the meander-folded notched stripline with dielectric supports and separators. Its design has been optimized using electromagnetic 3-D modeling with the MAFIA code package to provide rise and fall times in the range of 1 to 2 ns. A full-length (50 cm) prototype has been manufactured, and its preliminary measurements showed a good agreement with the calculations. Detailed measurements results and their comparison with simulations are presented. The latest front-end design requires a shorter, 35-cm chopper with a higher pulse voltage. Its meander-line current structure, based on the same principles, has also been optimized with MAFIA.

  20. Modeling of low- and high-frequency noise by slow and fast fluctuators

    Science.gov (United States)

    Nesterov, Alexander I.; Berman, Gennady P.

    2012-05-01

    We study the dynamics of dephasing in a quantum two-level system by modeling both 1/f and high-frequency noise by random telegraph processes. Our approach is based on a so-called spin-fluctuator model in which a noisy environment is modeled by a large number of fluctuators. In the continuous limit we obtain an effective random process (ERP) that is described by a distribution function of the fluctuators. In a simplified model, we reduce the ERP to the two (slow and fast) ensembles of fluctuators. Using this model, we study decoherence in a superconducting flux qubit and we compare our theoretical results with the available experimental data. We demonstrate good agreement of our theoretical predictions with the experiments. Our approach can be applied to many quantum systems, such as biological complexes, semiconductors, superconducting, and spin qubits, where the effects of interaction with the environment are essential.

  1. Modeling of Low and High Frequency Noise by Slow and Fast Fluctuators

    CERN Document Server

    Nesterov, Alexander I

    2012-01-01

    We study the dynamics of dephasing in a quantum two-level system by modeling both $1/f$ and high-frequency noise by random telegraph processes. Our approach is based on a so-called spin-fluctuator model in which a noisy environment is modelled by a large number of fluctuators. In the continuous limit we obtain an effective random process (ERP) that is described by a distribution function of the fluctuators. In a simplified model, we reduce the ERP to the two (slow and fast) effective fluctuators. Using this model, we study decoherence in a superconducting flux qubit and we compare our theoretical results with the available experimental data. We demonstrate good agreement of our theoretical predictions with the experiments. Our approach can be applied to many quantum systems, such as photosynthetic complexes, semiconductors, and superconducting and spin qubits, where the effects of interaction with the environment are essential.

  2. Rigorous mathematical modelling for a Fast Corrector Power Supply in TPS

    Science.gov (United States)

    Liu, K.-B.; Liu, C.-Y.; Chien, Y.-C.; Wang, B.-S.; Wong, Y. S.

    2017-04-01

    To enhance the stability of beam orbit, a Fast Orbit Feedback System (FOFB) eliminating undesired disturbances was installed and tested in the 3rd generation synchrotron light source of Taiwan Photon Source (TPS) of National Synchrotron Radiation Research Center (NSRRC). The effectiveness of the FOFB greatly depends on the output performance of Fast Corrector Power Supply (FCPS); therefore, the design and implementation of an accurate FCPS is essential. A rigorous mathematical modelling is very useful to shorten design time and improve design performance of a FCPS. A rigorous mathematical modelling derived by the state-space averaging method for a FCPS in the FOFB of TPS composed of a full-bridge topology is therefore proposed in this paper. The MATLAB/SIMULINK software is used to construct the proposed mathematical modelling and to conduct the simulations of the FCPS. Simulations for the effects of the different resolutions of ADC on the output accuracy of the FCPS are investigated. A FCPS prototype is realized to demonstrate the effectiveness of the proposed rigorous mathematical modelling for the FCPS. Simulation and experimental results show that the proposed mathematical modelling is helpful for selecting the appropriate components to meet the accuracy requirements of a FCPS.

  3. Development and evaluation of fast forming nano-composite hydrogel for ocular delivery of diclofenac.

    Science.gov (United States)

    Li, Xingyi; Zhang, Zhaoliang; Chen, Hao

    2013-05-01

    In this paper, a fast forming nano-composite hydrogel was developed for potential application in ocular drug delivery. The optical transmission (OT) as well as rheological properties of nano-composite hydrogel was characterized. The developed nano-composite hydrogel given a high diclofenac micelles loading and provided a sustained release manner of diclofenac within 6h. The developed nano-composite hydrogel formulation was administrated into the eye as flowable solution, quickly forming a hydrogel that is able to resist of the blinking and flushing of tear, yet resulting in the prolonged residence time of pre-corneal. In vivo eye irritation test suggested that the developed nano-composite hydrogel was none-eye irritation might be suitable for various ocular applications. In vivo pharmacokinetic study indicated that the developed nano-composite hydrogel could significantly increase the bioavailability of diclofenac and maintain the concentration of diclofenac in aqueous humor above MEC at least 24h after administration as compared with that of the commercial diclofenac sodium eye drops, which might be able to reduce the frequency of administration for patients.

  4. RTTOV-gb - adapting the fast radiative transfer model RTTOV for the assimilation of ground-based microwave radiometer observations

    Science.gov (United States)

    De Angelis, Francesco; Cimini, Domenico; Hocking, James; Martinet, Pauline; Kneifel, Stefan

    2016-08-01

    Ground-based microwave radiometers (MWRs) offer a new capability to provide continuous observations of the atmospheric thermodynamic state in the planetary boundary layer. Thus, they are potential candidates to supplement radiosonde network and satellite data to improve numerical weather prediction (NWP) models through a variational assimilation of their data. However in order to assimilate MWR observations, a fast radiative transfer model is required and such a model is not currently available. This is necessary for going from the model state vector space to the observation space at every observation point. The fast radiative transfer model RTTOV is well accepted in the NWP community, though it was developed to simulate satellite observations only. In this work, the RTTOV code has been modified to allow for simulations of ground-based upward-looking microwave sensors. In addition, the tangent linear, adjoint, and K-modules of RTTOV have been adapted to provide Jacobians (i.e., the sensitivity of observations to the atmospheric thermodynamical state) for ground-based geometry. These modules are necessary for the fast minimization of the cost function in a variational assimilation scheme. The proposed ground-based version of RTTOV, called RTTOV-gb, has been validated against accurate and less time-efficient line-by-line radiative transfer models. In the frequency range commonly used for temperature and humidity profiling (22-60 GHz), root-mean-square brightness temperature differences are smaller than typical MWR uncertainties (˜ 0.5 K) at all channels used in this analysis. Brightness temperatures (TBs) computed with RTTOV-gb from radiosonde profiles have been compared with nearly simultaneous and co-located ground-based MWR observations. Differences between simulated and measured TBs are below 0.5 K for all channels except for the water vapor band, where most of the uncertainty comes from instrumental errors. The Jacobians calculated with the K-module of RTTOV

  5. New modelling method for fast reactor neutronic behaviours analysis; Nouvelles methodes de modelisation neutronique des reacteurs rapides de quatrieme Generation

    Energy Technology Data Exchange (ETDEWEB)

    Jacquet, P.

    2011-05-23

    Due to safety rules running on fourth generation reactors' core development, neutronics simulation tools have to be as accurate as never before. First part of this report enumerates every step of fast reactor's neutronics simulation implemented in current reference code: ECCO. Considering the field of fast reactors that meet criteria of fourth generation, ability of models to describe self-shielding phenomenon, to simulate neutrons leakage in a lattice of fuel assemblies and to produce representative macroscopic sections is evaluated. The second part of this thesis is dedicated to the simulation of fast reactors' core with steel reflector. These require the development of advanced methods of condensation and homogenization. Several methods are proposed and compared on a typical case: the ZONA2B core of MASURCA reactor. (author) [French] Les criteres de surete qui regissent le developpement de coeurs de reacteurs de quatrieme generation implique l'usage d'outils de calcul neutronique performants. Une premiere partie de la these reprend toutes les etapes de modelisation neutronique des reacteurs rapides actuellement d'usage dans le code de reference ECCO. La capacite des modeles a decrire le phenomene d'autoprotection, a representer les fuites neutroniques au niveau d'un reseau d'assemblages combustibles et a generer des sections macroscopiques representatives est appreciee sur le domaine des reacteurs rapides innovants respectant les criteres de quatrieme generation. La deuxieme partie de ce memoire se consacre a la modelisation des coeurs rapides avec reflecteur acier. Ces derniers necessitent le developpement de methodes avancees de condensation et d'homogenisation. Plusieurs methodes sont proposees et confrontees sur un probleme de modelisation typique: le coeur ZONA2B du reacteur maquette MASURCA

  6. Development of fuel flow monitoring system in prototype fast breeder reactor 'MONJU'

    Energy Technology Data Exchange (ETDEWEB)

    Tomura, Katsuji; Deshimaru; Takehide; Okuda, Yoshihisa; Ohba, Toshio (Power Reactor and Nuclear Fuel Development Corp., Tsuruga, Fukui (Japan). Monju Construction Office); Ishikawa, Kouichi

    1994-06-01

    A new safeguards approach of Prototype Fast Breeder Reactor 'MONJU' has been studied by Japanese Government, IAEA and PNC to meet 1991-1995 safeguards criteria. As the result, a fuel flow monitoring system has been introduced in 'MONJU'. Development of the system has been conducted by PNC and IAEA with technical support of Los Alamos National Laboratory. Safeguards measures in unattended mode with the system can detect fuel loading and unloading into and from the reactor core and distinguish what kind of the fuel. The system are consisted of three monitors using neutron and gamma-ray measurements and video surveillance system. Installation of these monitors was finished by PNC and acceptance test by Japanese Government and IAEA was carried out March, 1992. (author).

  7. Development of growth rate measuring method for intracellular, parasitic acid-fast bacteria using radioisotopes

    Energy Technology Data Exchange (ETDEWEB)

    Nakata, Noboru; Fukutomi, Yasuo [National Inst. of Infectious Deseases, Tokyo (Japan)

    1998-02-01

    To prevent and treat infections diseases caused by pathogenic acid-fast bacteria such as Mycobacterium leprae, Tubercle bacillus, it is important to elucidate the mechanisms of intracellular proliferations of these bacteria. This research project was started to make DNA library using a new constructed shuttle vector. Development of in vitro evaluation method for intracellular proliferation of mycobacterium and its transformed cells was attempted on the basis of Buddemeyer method. This method was able to precisely determine the metabolic activities as low as those in leprae and its modified method using {sup 14}C-palmitic acid was highly sensitive and the results were obtainable in a shorter period. The generated CO{sub 2} was satisfactorily absorbed into scintillator without using a filter paper. A new culture medium from which arginine, a NO-producing compound was eliminated was used to repress the sterilizing effects of NO, but the metabolic activities of leprae was not enhanced. (M.N.)

  8. Development of a fast traveling-wave beam chopper for the National Spallation Neutron Source

    Energy Technology Data Exchange (ETDEWEB)

    Kurennoy, S.S.; Jason, A.J.; Krawczyk, F.L.; Power, J.

    1997-10-01

    High current and severe restrictions on beam losses, below 1 nA/m, in the designed linac for the National Spallation Neutron Source (NSNS) require clean and fast--with the rise time from 2% to 98% less than 2.5 ns to accommodate a 402.5-MHz beam structure--beam chopping in its front end, at the beam energy 2.5 MeV. The R and D program includes both modification of the existing LANSCE coax-plate chopper to reduce parasitic coupling between adjacent plates, and development of new traveling-wave deflecting structures, in particular, based on a meander line. Using analytical methods and three-dimensional time-domain computer simulations the authors study transient effects in such structures to choose an optimal chopper design.

  9. Development of a Fast Traveling-Wave Beam Chopper for National Spallation Neutron Source.

    Science.gov (United States)

    Kurennoy, Sergey S.; Jason, Andrew J.; Krawczyk, Frank L.

    1997-05-01

    High current and severe restrictions on beam losses, below 1 nA/m, in the designed linac for the NSNS require clean and fast (with the rise time from 2% to 98% less than 2.5 ns to accommodate a 402.5 MHz beam structure) beam chopping in its front end, at beam energy 2.5 MeV. The present R&D program includes both modification of the existing LANSCE coax-plate chopper to reduce parasitic coupling between adjacent plates, and development of new traveling-wave deflecting structures, in particular, based on a meander line. Using analytical methods and three-dimensional time-domain computer simulations we study transient effects in such structures to choose an optimal chopper design.

  10. Development and tests of fast 1-MA linear transformer driver stages

    Directory of Open Access Journals (Sweden)

    A. A. Kim

    2009-05-01

    Full Text Available In this article we present the design and test results of the most powerful, fast linear transformer driver (LTD stage developed to date. This 1-MA LTD stage consists of 40 parallel RLC (resistor R, inductor L, and capacitor C circuits called “bricks” that are triggered simultaneously; it is able to deliver ∼1  MA current pulse with a rise time of ∼100  ns into the ∼0.1-Ohm matched load. The electrical behavior of the stage can be predicted by using a simple RLC circuit, thus simplifying the designing of various LTD-based accelerators. Five 1-MA LTD stages assembled in series into a module have been successfully tested with both resistive and vacuum electron-beam diode loads.

  11. Development of a fast readout system of an X-ray CCD

    CERN Document Server

    Awaki, H; Koyama, K; Tomida, H; Tsuru, T

    1999-01-01

    In the course of developing a fast readout system of an X-ray CCD camera with low noise using HPK-CCD, we have succeeded in making a clock generator to read data from a CCD with the speed of 2 Mpixel/s. This generator is fabricated from commercially available products in order to simplify the manufacturing procedure. To determine the noise of the system, we are evaluating the noise from each part which conceivably contributes. It is known that the readout noise depends on the clock speed. Thus, to begin with, we measured the dependency of the system noise from the ADC in the data acquisition system on its clock speed.

  12. Development of a fast proton range radiography system for quality assurance in hadrontherapy

    Science.gov (United States)

    Bucciantonio, M.; Amaldi, U.; Kieffer, R.; Sauli, F.; Watts, D.

    2013-12-01

    We describe the development of a Proton Range Radiography system with an imaging area of 30×30 cm2 for two dimensional mapping of the integrated density in a target. Proton transmission radiographic images are produced by measuring, with a pair of position-sensitive detectors (GEM chambers), the direction of the protons transmitted through the patient and, with a stack of scintillators, the residual range of the protons leaving the patient. To match the data rate requirements of an in-beam diagnostic, a novel data acquisition system for the tracking detectors has been designed to operate at 1 MHz data flow. Laboratory tests exposing the GEM detector with high flux X-rays confirm the fast response of the new data acquisition system. Images of several phantoms have been recorded to demonstrate the GEM position accuracy.

  13. Development of a fast proton range radiography system for quality assurance in hadrontherapy

    Energy Technology Data Exchange (ETDEWEB)

    Bucciantonio, M., E-mail: martina.bucciantonio@cern.ch [Tera Foundation, Novara (Italy); Albert Einstein Center for Fundamental Physics, Laboratory for High Energy Physics, University of Bern, Bern (Switzerland); Amaldi, U.; Kieffer, R.; Sauli, F.; Watts, D. [Tera Foundation, Novara (Italy)

    2013-12-21

    We describe the development of a Proton Range Radiography system with an imaging area of 30×30 cm{sup 2} for two dimensional mapping of the integrated density in a target. Proton transmission radiographic images are produced by measuring, with a pair of position-sensitive detectors (GEM chambers), the direction of the protons transmitted through the patient and, with a stack of scintillators, the residual range of the protons leaving the patient. To match the data rate requirements of an in-beam diagnostic, a novel data acquisition system for the tracking detectors has been designed to operate at 1 MHz data flow. Laboratory tests exposing the GEM detector with high flux X-rays confirm the fast response of the new data acquisition system. Images of several phantoms have been recorded to demonstrate the GEM position accuracy.

  14. Mobilization of mercury from lean tissues during simulated migratory fasting in a model songbird.

    Science.gov (United States)

    Seewagen, Chad L; Cristol, Daniel A; Gerson, Alexander R

    2016-05-12

    The pollutant methylmercury accumulates within lean tissues of birds and other animals. Migrating birds catabolize substantial amounts of lean tissue during flight which may mobilize methylmercury and increase circulating levels of this neurotoxin. As a model for a migrating songbird, we fasted zebra finches (Taeniopygia guttata) that had been dosed with 0.0, 0.1, and 0.6 parts per million (ppm) dietary methylmercury and measured changes in blood total mercury concentrations (THg) in relation to reductions in lean mass. Birds lost 6-16% of their lean mass during the fast, and THg increased an average of 12% and 11% in the 0.1 and 0.6 ppm treatments, respectively. Trace amounts of THg in the 0.0 ppm control group also increased as a result of fasting, but remained extremely low. THg increased 0.4 ppm for each gram of lean mass catabolized in the higher dose birds. Our findings indicate that methylmercury is mobilized from lean tissues during protein catabolism and results in acute increases in circulating concentrations. This is a previously undocumented potential threat to wild migratory birds, which may experience greater surges in circulating methylmercury than demonstrated here as a result of their greater reductions in lean mass.

  15. Fast modeling of flux trapping cascaded explosively driven magnetic flux compression generators.

    Science.gov (United States)

    Wang, Yuwei; Zhang, Jiande; Chen, Dongqun; Cao, Shengguang; Li, Da; Liu, Chebo

    2013-01-01

    To predict the performance of flux trapping cascaded flux compression generators, a calculation model based on an equivalent circuit is investigated. The system circuit is analyzed according to its operation characteristics in different steps. Flux conservation coefficients are added to the driving terms of circuit differential equations to account for intrinsic flux losses. To calculate the currents in the circuit by solving the circuit equations, a simple zero-dimensional model is used to calculate the time-varying inductance and dc resistance of the generator. Then a fast computer code is programmed based on this calculation model. As an example, a two-staged flux trapping generator is simulated by using this computer code. Good agreements are achieved by comparing the simulation results with the measurements. Furthermore, it is obvious that this fast calculation model can be easily applied to predict performances of other flux trapping cascaded flux compression generators with complex structures such as conical stator or conical armature sections and so on for design purpose.

  16. Transonic Drag Reduction Through Trailing-Edge Blowing on the FAST-MAC Circulation Control Model

    Science.gov (United States)

    Chan, David T.; Jones, Gregory S.; Milholen, William E., II; Goodliff, Scott L.

    2017-01-01

    A third wind tunnel test of the FAST-MAC circulation control semi-span model was completed in the National Transonic Facility at the NASA Langley Research Center where the model was configured for transonic testing of the cruise configuration with 0deg flap detection to determine the potential for transonic drag reduction with the circulation control blowing. The model allowed independent control of four circulation control plenums producing a high momentum jet from a blowing slot near the wing trailing edge that was directed over a 15% chord simple-hinged ap. Recent upgrades to transonic semi-span flow control testing at the NTF have demonstrated an improvement to overall data repeatability, particularly for the drag measurement, that allows for increased confidence in the data results. The static thrust generated by the blowing slot was removed from the wind-on data using force and moment balance data from wind-o thrust tares. This paper discusses the impact of the trailing-edge blowing to the transonic aerodynamics of the FAST-MAC model in the cruise configuration, where at flight Reynolds numbers, the thrust-removed corrected data showed that an overall drag reduction and increased aerodynamic efficiency was realized as a consequence of the blowing.

  17. Accurate Cure Modeling for Isothermal Processing of Fast Curing Epoxy Resins

    Directory of Open Access Journals (Sweden)

    Alexander Bernath

    2016-11-01

    Full Text Available In this work a holistic approach for the characterization and mathematical modeling of the reaction kinetics of a fast epoxy resin is shown. Major composite manufacturing processes like resin transfer molding involve isothermal curing at temperatures far below the ultimate glass transition temperature. Hence, premature vitrification occurs during curing and consequently has to be taken into account by the kinetic model. In order to show the benefit of using a complex kinetic model, the Kamal-Malkin kinetic model is compared to the Grindling kinetic model in terms of prediction quality for isothermal processing. From the selected models, only the Grindling kinetic is capable of taking into account vitrification. Non-isothermal, isothermal and combined differential scanning calorimetry (DSC measurements are conducted and processed for subsequent use for model parametrization. In order to demonstrate which DSC measurements are vital for proper cure modeling, both models are fitted to varying sets of measurements. Special attention is given to the evaluation of isothermal DSC measurements which are subject to deviations arising from unrecorded cross-linking prior to the beginning of the measurement as well as from physical aging effects. It is found that isothermal measurements are vital for accurate modeling of isothermal cure and cannot be neglected. Accurate cure predictions are achieved using the Grindling kinetic model.

  18. PyTransit: Fast and Easy Exoplanet Transit Modelling in Python

    CERN Document Server

    Parviainen, Hannu

    2015-01-01

    We present a fast and user friendly exoplanet transit light curve modelling package PyTransit, implementing optimised versions of the Gimen\\'ez and the Mandel & Agol transit models. The package offers an object-oriented Python interface to access the two models implemented natively in Fortran with OpenMP parallelisation. A partial OpenCL version of the quadratic Mandel-Agol model is also included for GPU-accelerated computations. The aim of PyTransit is to facilitate the analysis of photometric time series of exoplanet transits consisting of hundreds of thousands of datapoints, and of multi-passband transit light curves from spectrophotometric observations, as a part of a researcher's programming toolkit for building complex, problem-specific, analyses.

  19. Passive acoustic leak detection for sodium cooled fast reactors using hidden Markov models

    Energy Technology Data Exchange (ETDEWEB)

    Riber Marklund, A. [CEA, Cadarache, DEN/DTN/STCP/LIET, Batiment 202, 13108 St Paul-lez-Durance, (France); Kishore, S. [Fast Reactor Technology Group of IGCAR, (India); Prakash, V. [Vibrations Diagnostics Division, Fast Reactor Technology Group of IGCAR, (India); Rajan, K.K. [Fast Reactor Technology Group and Engineering Services Group of IGCAR, (India)

    2015-07-01

    Acoustic leak detection for steam generators of sodium fast reactors have been an active research topic since the early 1970's and several methods have been tested over the years. Inspired by its success in the field of automatic speech recognition, we here apply hidden Markov models (HMM) in combination with Gaussian mixture models (GMM) to the problem. To achieve this, we propose a new feature calculation scheme, based on the temporal evolution of the power spectral density (PSD) of the signal. Using acoustic signals recorded during steam/water injection experiments done at the Indira Gandhi Centre for Atomic Research (IGCAR), the proposed method is tested. We perform parametric studies on the HMM+GMM model size and demonstrate that the proposed method a) performs well without a priori knowledge of injection noise, b) can incorporate several noise models and c) has an output distribution that simplifies false alarm rate control. (authors)

  20. Experimental studies of heat exchange for sodium boiling in the fuel assembly model: Safety substantiation of a promising fast reactor

    Science.gov (United States)

    Khafizov, R. R.; Poplavskii, V. M.; Rachkov, V. I.; Sorokin, A. P.; Trufanov, A. A.; Ashurko, Yu. M.; Volkov, A. V.; Ivanov, E. F.; Privezentsev, V. V.

    2017-01-01

    Numerical simulation of the ULOF-type accident development in a fast reactor with sodium coolant performed using the COREMELT code indicates that sodium boiling in the active core takes place. The boiling is accompanied by oscillations of the technological parameters of the reactor installation; these oscillations can go on during several tens of seconds. In this case, it is possible that a stable regime of removal of heat from residual energy release is implemented. The model of the two-phase coolant flow applied in the code has an important effect on the numerical results; that is why this model needs experimental verification. For eliminating the development of an accident resulting in destruction of the active core elements, a structural solution is proposed; the essence of it is the application of the sodium void above the reactor active core. The experimental installation was developed and the heat exchange at sodium boiling in the model fuel assembly of the fast reactor in the regimes of natural and forced circulation in the presence of the sodium void and the top end shield was studied. It was demonstrated that, in the presence of the sodium void, it is possible to provide long-term cooling of the fuel assembly for a thermal flux density on the fuel element simulator surface of up to 140 and 170 kW/m2 in the natural and forced circulation modes, respectively. The obtained data are used for more precise determination of the numerical model of sodium boiling in the fuel assembly and verification of the COREMELT code.

  1. A Fast Version of LASG/IAP Climate System Model and Its 1000-year Control Integration

    Institute of Scientific and Technical Information of China (English)

    ZHOU Tianjun; WU Bo; WEN Xinyu; LI Lijuan; WANG Bin

    2008-01-01

    A fast version of the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geo- physical Fluid Dynamics (LASG)/Institute of Atmospheric Physics (IAP) climate system model is briefly documented. The fast coupled model employs a low resolution version of the atmospheric component Grid Atmospheric Model of IAP/LASG (GAMIL), with the other parts of the model, namely an oceanic com- ponent LASG/IAP Climate Ocean Model (LICOM), land component Common Land Model (CLM), and sea ice component from National Center for Atmospheric Research Community Climate System Model (NCAR CCSM2), as the same as in the standard version of LASG/IAP Flexible Global Ocean Atmosphere Land System model (FGOALS_g). The parameterizatious of physical and dynamical processes of the at- mospheric component in the fast version are identical to the standard version, although some parameter values are different. However, by virtue of reduced horizontal resolution and increased time-step of the most time-consuming atmospheric component, it runs faster by a factor of 3 and can serve as a useful tool for long- term and large-ensemble integrations. A 1000-year control simulation of the present-day climate has been completed without flux adjustments. The final 600 years of this simulation has virtually no trends in global mean sea surface temperatures and is recommended for internal variability studies. Several aspects of the control simulation's mean climate and variability axe evaluated against the observational or reanalysis data. The strengths and weaknesses of the control simulation are evaluated. The mean atmospheric circulation is well simulated, except in high latitudes. The Asian-Australian monsoonal meridional cell shows realistic features, however, an artificial rainfall center is located to the eastern periphery of the Tibetan Plateau persists throughout the year. The mean bias of SST resembles that of the standard version, appearing as a "double ITCZ" (Inter

  2. A practical approach to fast-light enhanced fiber sensing: experiments and modeling

    Science.gov (United States)

    Christensen, Caleb A.; Zavriyev, Anton; Cummings, Malcolm; Beal, A. Craig; Lucas, Mark; Lagasse, Michael

    2014-06-01

    It has been proposed that fast-light optical phenomena can increase the sensitivity of an optical gyroscope of a given size by several orders of magnitude. MagiQ Technologies is developing a compact fiber-based fast light Inertial Measurement Unit (IMU) using Stimulated Brillouin Scattering (SBS) in optical fibers with commercially mature technologies. We have demonstrated repeatable fast-light effects in the lab using off-the shelf optical components. Numerical analysis has revealed the requirements for stable, sensitive operation of gyroscopes, accelerometers or other sensors, as well as identified methods for optimizing efficiency, size, and reliability with known optical technologies. By using photonic integrated circuits and telecom-grade components along with specialty fibers, our design would be appropriate for mass production. We have eliminated all free-space optical elements or wavelength dependent elements such as atomic vapor cells in order to enable a compact, high sensitivity IMU stable against environmental disturbances. Results of this effort will have benefits in existing applications of IMUs (such as inertial navigation units, gyrocompasses, and stabilization techniques), and will allow wider use of RLGs in spacecraft, unmanned aerial vehicles or sensors, where the current size and weight of optical IMUs are prohibitive.

  3. Conceptualising the management of packaging within new product development:a grounded investigation in the UK fast moving consumer goods industry

    OpenAIRE

    Simms, Chris; Trott, Paul

    2014-01-01

    Purpose- The purpose of this study is to: (i) contribute to existing models of new product development (NPD), and provide new understanding of how a new product’s packaging is managed and integrated into the NPD process of fast moving consumer goods firms; and (ii) build on prior research suggesting that firms lack a pipeline of new packaging innovations by uncovering the factors that influence this pipeline issue. Design/methodology/approach- A grounded theory methodology was adopted. Resear...

  4. Building and Calibration of a FAST Model of the SWAY Prototype Floating Wind Turbine: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Koh, J. H.; Robertson, A.; Jonkman, J.; Driscoll, F.; Ng, E. Y. K.

    2013-09-01

    Present efforts to verify and validate aero-hydro-servo-elastic numerical simulation tools that predict the dynamic response of a floating offshore wind turbine are primarily limited to code-to-code comparisons or code-to-data comparisons using data from wind-wave basin tests. In partnership with SWAY AS, the National Renewable Energy Laboratory (NREL) installed scientific wind, wave, and motion measurement equipment on the 1/6.5th-scale prototype SWAY floating wind system to collect data to validate a FAST model of the SWAY design in an open-water condition. Nanyang Technological University (NTU), through a collaboration with NREL, assisted in this validation.

  5. Calibration, characterisation and Monte Carlo modelling of a fast-UNCL

    Energy Technology Data Exchange (ETDEWEB)

    Tagziria, Hamid, E-mail: hamid.tagziria@jrc.ec.europa.eu [European Commission, Joint Research Center, ITU-Nuclear Security Unit, I-21027 Ispra (Italy); Bagi, Janos; Peerani, Paolo [European Commission, Joint Research Center, ITU-Nuclear Security Unit, I-21027 Ispra (Italy); Belian, Antony [Department of Safeguards, SGTS/TAU, IAEA Vienna Austria (Austria)

    2012-09-21

    This paper describes the calibration, characterisation and Monte Carlo modelling of a new IAEA Uranium Neutron Collar (UNCL) for LWR fuel, which can be operated in both passive and active modes. It can employ either 35 {sup 3}He tubes (in active configuration) or 44 tubes at 10 atm pressure (in its passive configuration) and thus can be operated in fast mode (with Cd liner) as its efficiency is higher than that of the standard UNCL. Furthermore, it has an adjustable internal cavity which allows the measurement of varying sizes of fuel assemblies such as WWER, PWR and BWR. It is intended to be used with Cd liners in active mode (with an AmLi interrogation source in place) by the inspectorate for the determination of the {sup 235}U content in fresh fuel assemblies, especially in cases where high concentrations of burnable poisons cause problems with accurate assays. A campaign of measurements has been carried out at the JRC Performance Laboratories (PERLA) in Ispra (Italy) using various radionuclide neutron sources ({sup 252}Cf, {sup 241}AmLi and PuGa) and our BWR and PWR reference assemblies, in order to calibrate and characterise the counter as well as assess its performance and determine its optimum operational parameters. Furthermore, the fast-UNCL has been extensively modelled at JRC using the Monte Carlo code, MCNP-PTA, which simulates both the neutron transport and the coincidence electronics. The model has been validated using our measurements which agreed well with calculations. The WWER1000 fuel assembly for which there are no representative reference materials for an adequate calibration of the counter, has also been modelled and the response of the counter to this fuel assembly has been simulated. Subsequently numerical calibrations curves have been obtained for the above fuel assemblies in various modes (fast and thermal). The sensitivity of the counter to fuel rods substitution as well as other important aspects and the parameters of the fast

  6. Ultra-fast fiber lasers principles and applications with Matlab models

    CERN Document Server

    Binh, Le Nguyen

    2010-01-01

    Ultrashort pulses in mode-locked lasers are receiving focused attention from researchers looking to apply them in a variety of fields, from optical clock technology to measurements of the fundamental constants of nature and ultrahigh-speed optical communications. Ultrashort pulses are especially important for the next generation of ultrahigh-speed optical systems and networks operating at 100 Gbps per carrier. Ultra Fast Fiber Lasers: Principles and Applications with MATLAB(R) Models is a self-contained reference for engineers and others in the fields of applied photonics and optical communica

  7. Two-point correlators revisited: Fast and slow scales in multifield models of Inflation

    CERN Document Server

    Ghersi, José T Gálvez

    2016-01-01

    We study the structure of two-point correlators of the inflationary field fluctuations in order to improve the accuracy and efficiency of the existing spectral methods. We present a description motivated by the separation of the fast and slow evolving components of the spectrum. Our purpose is to rephrase all the relevant equations of motion in terms of slowly varying quantities. This is important in order to consider the contribution from high-frequency modes to the spectrum without affecting computational performance. The slow-roll approximation is not required to reproduce the main distinctive features in the power spectrum for each specific model of inflation.

  8. Ozone affects gas exchange, growth and reproductive development in Brassica campestris (Wisconsin fast plants).

    Science.gov (United States)

    Black, V J; Stewart, C A; Roberts, J A; Black, C R

    2007-01-01

    Exposure to ozone (O(3)) may affect vegetative and reproductive development, although the consequences for yield depend on the effectiveness of the compensatory processes induced. This study examined the impact on reproductive development of exposing Brassica campestris (Wisconsin Fast Plants) to ozone during vegetative growth. Plants were exposed to 70 ppb ozone for 2 d during late vegetative growth or 10 d spanning most of the vegetative phase. Effects on gas exchange, vegetative growth, reproductive development and seed yield were determined. Impacts on gas exchange and foliar injury were related to pre-exposure stomatal conductance. Exposure for 2 d had no effect on growth or reproductive characteristics, whereas 10-d exposure reduced vegetative growth and reproductive site number on the terminal raceme. Mature seed number and weight per pod and per plant were unaffected because seed abortion was reduced. The observation that mature seed yield per plant was unaffected by exposure during the vegetative phase, despite adverse effects on physiological, vegetative and reproductive processes, shows that indeterminate species such as B. campestris possess sufficient compensatory flexibility to avoid reductions in seed production.

  9. Modelling of stratification in cryogenic launch vehicle tanks in a fast engineering tool

    Science.gov (United States)

    van Foreest, Arnold

    Modelling of stratification in cryogenic launch vehicle tanks in a fast engineering tool Thermal stratification in cryogenic launch vehicle tanks can lead to several problems, such as sudden pressure drops in the tank due to sloshing of the stratified liquid or cavitation in rocket engine turbopumps. To obtain an optimal stage design, the stratification process muss be taken into account. Currently, stratification is often modelled by 3D CFD solvers, which is an extremely time consuming process. Analytical models do exists but are inaccurate. This paper will show how the currently existing analytical models are improved, by using experimental data and results obtained from numerical calculations using the 3D CFD tool FLOW 3D. The goal is to be able to model a stratification process of a few hundred seconds in just a few seconds of CPU time, so about a factor 100 faster than the physical process takes. A simulation using a 3D flow solver can take multiple days. Setting up the model for a 3D flow solver can even take longer. Therefore it would be a big advantage to have fast engineering tools describing the process so that stratification can be taken into account in the preliminary design phase. The stratification process has been investigated experimentally at ZARM (Centre of Applied Spaceflight and Microgravity), using a closed tank filled with liquid nitrogen. Due to unavoidable heat leaks from the surrounding, the liquid will start to heat up and thermal layers will form. The experiments are simulated using the commercial 3D flow solver "FLOW 3D". Once satisfying numerical results have been obtained, the stratification process can be investigated in more detail. The dimensioning parameters can be determined and their influence can be quantified. From these analyses it has been found that for example heat conduction through the tank wall in tangential direction has a big impact on the formation of thermal layers. The currently available analytical models for

  10. Acoustic monitoring of sodium boiling in a liquid metal fast breeder reactor from autoregressive models

    Energy Technology Data Exchange (ETDEWEB)

    Geraldo, Issa Cherif [Laboratoire d’Automatique, Génie Informatique et Signal (LAGIS UMR CNRS 8219), Université Lille 1, Sciences et technologies, Avenue Paul Langevin, BP 48, 59651 Villeneuve d’Ascq CEDEX (France); Bose, Tanmoy [Indian Institute of Technology Kharagpur, Kharagpur 721302, West Bengal (India); Pekpe, Komi Midzodzi, E-mail: midzodzi.pekpe@univ-lille1.fr [Laboratoire d’Automatique, Génie Informatique et Signal (LAGIS UMR CNRS 8219), Université Lille 1, Sciences et technologies, Avenue Paul Langevin, BP 48, 59651 Villeneuve d’Ascq CEDEX (France); Cassar, Jean-Philippe [Laboratoire d’Automatique, Génie Informatique et Signal (LAGIS UMR CNRS 8219), Université Lille 1, Sciences et technologies, Avenue Paul Langevin, BP 48, 59651 Villeneuve d’Ascq CEDEX (France); Mohanty, A.R. [Indian Institute of Technology Kharagpur, Kharagpur 721302, West Bengal (India); Paumel, Kévin [CEA, DEN, Nuclear Technology Department, F-13108 Saint-Paul-lez-Durance (France)

    2014-10-15

    Highlights: • The work deals with sodium boiling detection in a liquid metal fast breeder reactor. • The authors choose to use acoustic data instead of thermal data. • The method is designed to not to be disturbed by the environment noises. • A real time boiling detection methods are proposed in the paper. - Abstract: This paper deals with acoustic monitoring of sodium boiling in a liquid metal fast breeder reactor (LMFBR) based on auto regressive (AR) models which have low computational complexities. Some authors have used AR models for sodium boiling or sodium–water reaction detection. These works are based on the characterization of the difference between fault free condition and current functioning of the system. However, even in absence of faults, it is possible to observe a change in the AR models due to the change of operating mode of the LMFBR. This sets up the delicate problem of how to distinguish a change in operating mode in absence of faults and a change due to presence of faults. In this paper we propose a new approach for boiling detection based on the estimation of AR models on sliding windows. Afterwards, classification of the models into boiling or non-boiling models is made by comparing their coefficients by two statistical methods, multiple linear regression (LR) and support vectors machines (SVM). The proposed approach takes into account operating mode information in order to avoid false alarms. Experimental data include non-boiling background noise data collected from Phenix power plant (France) and provided by the CEA (Commissariat à l’Energie Atomique et aux énergies alternatives, France) and boiling condition data generated in laboratory. High boiling detection rates as well as low false alarms rates obtained on these experimental data show that the proposed method is efficient for boiling detection. Most importantly, it shows that the boiling phenomenon introduces a disturbance into the AR models that can be clearly detected.

  11. SPH modeling of adhesion in fast dynamics: Application to the Cold Spray process

    Science.gov (United States)

    Profizi, Paul; Combescure, Alain; Ogawa, Kahuziro

    2016-04-01

    The objective of this paper is to show, in a specific case, the importance of modeling adhesive forces when simulating the bouncing of very small particles impacting a substrate at high speed. The implementation of this model into a fast-dynamics SPH code is described. Taking the example of an impacted elastic cylinder, we show that the adhesive forces, which are surface forces, play a significant role only if the particles are sufficiently small. The effect of the choice of the type of interaction law in the cohesive zone is studied and some conclusions on the relevance of the modeling of the adhesive forces for fast-dynamics impacts are drawn. Then, the adhesion model is used to simulate the Cold Spray process. An aluminum particle is projected against a substrate made of the same material at a velocity ranging from 200 to 1000 m ṡs-1. We study the effects of the various modeling assumptions on the final result: bouncing or sticking. Increasingly complex models are considered. At a 200 m ṡs-1 impact velocity, elastic behavior is assumed, the substrate being simply supported at its base and supplied with absorbing boundaries. The same absorbing boundaries are also used for all the other simulations. Then, plasticity is introduced and the impact velocity is increased up to 1000 m ṡs-1. At the highest velocities, the resulting strains are very significant. The calculations show that if the adhesion model is appropriately chosen, it is possible to reproduce the experimental observations: the particles stick to the substrate in a range of impact velocities surrounded by two velocity ranges in which the particles bounce.

  12. Developing a model: an illustration.

    Science.gov (United States)

    Havenga, Yolanda; Poggenpoel, Marie; Myburgh, Chris

    2014-04-01

    Model development may seem a daunting task for the novice. The purpose of this article is to illustrate the steps of model development applied to a real-life phenomenon using an inductive theory-generating research approach. The value of the illustration is that nurse researchers can follow the application of the process as a point of departure for their own work. A logical stepwise discussion is followed for empirical theory development. The logical thought process from identifying the phenomenon to describing the model as a visual metaphor of the phenomenon is illustrated.

  13. Development Status of TRACE model for PGSFR Safety Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Andong; Choi, Yong Won; Kim, Jihun; Bae, Moohoon [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2014-05-15

    For the preparation of the review of licensing application for PGSFR, TRACE model for the PGSFR is being developed considering the sodium related properties and model in the code. For the use of licensing purpose, it is identified and need to be improved that model uncertainty in the code and conservative conditions for accident analysis is needs to be defined and validated. And current simulations are applicable only to assembly-averaged assessment. So it is also need to be defined for pin-wise assessment within hot assembly. On the basis on the developed model, PGSFR design change will be applied and improved for independent audit calculation for incoming licensing review. Prototype Generation IV Sodium cooled Fast Reactor (PGSFR) of 150MWe is under developing targeting licensing application by 2017. KINS is preparing review of its licensing application, especially the audit calculation tool for transient and accident analysis is being prepared for review. Since 2012, TRACE code applicability study has been doing for the Sodium-cooled Fast Reactor. At first, Sodium properties and the related heat transfer model in the code were reviewed. Demonstration Sodium cooled Fast Reactor (DSFR-600) were model and representing DBAs were assessed until the PGSFR design is fixed. EBR-II Shutdown Heat Removal Test (SHRT) experiment is also being analyzed in terms of IAEA Cooperated Research Program. In this paper, PGSFR TRACE code modeling status and considerations for SFR DBA assessment is introduced.

  14. FastGGM: An Efficient Algorithm for the Inference of Gaussian Graphical Model in Biological Networks.

    Science.gov (United States)

    Wang, Ting; Ren, Zhao; Ding, Ying; Fang, Zhou; Sun, Zhe; MacDonald, Matthew L; Sweet, Robert A; Wang, Jieru; Chen, Wei

    2016-02-01

    Biological networks provide additional information for the analysis of human diseases, beyond the traditional analysis that focuses on single variables. Gaussian graphical model (GGM), a probability model that characterizes the conditional dependence structure of a set of random variables by a graph, has wide applications in the analysis of biological networks, such as inferring interaction or comparing differential networks. However, existing approaches are either not statistically rigorous or are inefficient for high-dimensional data that include tens of thousands of variables for making inference. In this study, we propose an efficient algorithm to implement the estimation of GGM and obtain p-value and confidence interval for each edge in the graph, based on a recent proposal by Ren et al., 2015. Through simulation studies, we demonstrate that the algorithm is faster by several orders of magnitude than the current implemented algorithm for Ren et al. without losing any accuracy. Then, we apply our algorithm to two real data sets: transcriptomic data from a study of childhood asthma and proteomic data from a study of Alzheimer's disease. We estimate the global gene or protein interaction networks for the disease and healthy samples. The resulting networks reveal interesting interactions and the differential networks between cases and controls show functional relevance to the diseases. In conclusion, we provide a computationally fast algorithm to implement a statistically sound procedure for constructing Gaussian graphical model and making inference with high-dimensional biological data. The algorithm has been implemented in an R package named "FastGGM".

  15. Advanced Mirror & Modelling Technology Development

    Science.gov (United States)

    Effinger, Michael; Stahl, H. Philip; Abplanalp, Laura; Maffett, Steven; Egerman, Robert; Eng, Ron; Arnold, William; Mosier, Gary; Blaurock, Carl

    2014-01-01

    The 2020 Decadal technology survey is starting in 2018. Technology on the shelf at that time will help guide selection to future low risk and low cost missions. The Advanced Mirror Technology Development (AMTD) team has identified development priorities based on science goals and engineering requirements for Ultraviolet Optical near-Infrared (UVOIR) missions in order to contribute to the selection process. One key development identified was lightweight mirror fabrication and testing. A monolithic, stacked, deep core mirror was fused and replicated twice to achieve the desired radius of curvature. It was subsequently successfully polished and tested. A recently awarded second phase to the AMTD project will develop larger mirrors to demonstrate the lateral scaling of the deep core mirror technology. Another key development was rapid modeling for the mirror. One model focused on generating optical and structural model results in minutes instead of months. Many variables could be accounted for regarding the core, face plate and back structure details. A portion of a spacecraft model was also developed. The spacecraft model incorporated direct integration to transform optical path difference to Point Spread Function (PSF) and between PSF to modulation transfer function. The second phase to the project will take the results of the rapid mirror modeler and integrate them into the rapid spacecraft modeler.

  16. Two-dimensional models of early-type fast rotating stars: the ESTER project

    CERN Document Server

    Rieutord, Michel

    2015-01-01

    In this talk I present the latest results of the ESTER project that has taken up the challenge of building two dimensional (axisymmetric) models of stars rotating at any rotation rate. In particular, I focus on main sequence massive and intermediate mass stars. I show what should be expected in such stars as far as the differential rotation and the associated meridional circulation are concerned, notably the emergence of a Stewartson layer along the tangent cylinder of the core. I also indicate what may be inferred about the evolution of an intermediate-mass star at constant angular momentum and how Be stars may form. I finally give some comparisons between models and observations of the gravity darkening on some nearby fast rotators as it has been derived from interferometric observations. In passing, I also discuss how 2D models can help to recover the fundamental parameters of a star.

  17. Modeling and Analysis of the Motivations of Fast Fashion Consumers in Relation to Innovativeness

    Directory of Open Access Journals (Sweden)

    Saricam Canan

    2016-12-01

    Full Text Available In this study, fast fashion concept is investigated in order to understand the motivations of the consumers that make them adopt these products because of their willingness for the innovativeness. The relationship between the motivational factors which were named as “Social or status image” and “Uniqueness” as expressions of individuality, “Conformity” and the willingness for “Innovativeness” is analyzed using a conceptual model. Exploratory factor analysis, confirmatory factor analysis and structural equation modeling were used to analyze and validate the model. The data used for the study was obtained from 244 people living in Turkey. The findings showed that the motivational factors “Social or status image” and “Uniqueness” as expressions of individuality are influential on the consumers’ willingness for “Innovativeness”.

  18. Assessment of synthetic winds through spectral modeling and validation using FAST

    Science.gov (United States)

    Chougule, A.; Kandukuri, S. T.; Beyer, H. G.

    2016-09-01

    In this paper, we analyse the simulated and measured wind data with respect to their spectral characteristics and their effect on wind turbine loads. The synthetic data is generated from a stochastic full-field turbulent wind simulator - TurbSim for neutral stability conditions. We first investigate a model for velocity spectra and, a coherence model, by comparing the model results with the measurements. In the second part we analyse the synthetic data via spectra and coherence for two cases; without and with adding coherent events. Finally, we compare wind turbine loads calculated by using FAST simulation of 5 MW reference wind turbine on the basis of simulated and measured data for the given mean wind speed.

  19. Fast Propagation in Fluid Transport Models with Evolution of Turbulence Saturation

    Energy Technology Data Exchange (ETDEWEB)

    Lopez-Bruna, D.

    2012-07-01

    This report compiles and extends two works on models that reproduce the experimental facts of non local transport and pulse propagation in magnetically confined fusion plasmas. The works are based on fluid transport models, originally designed to explain the formation of edge or internal transport barriers, that include fast evolution equations for the particle and heat fluxes. The heating of the plasma core in response to a sudden edge cooling or the propagation of turbulent fronts around transport barriers are a consequence of the competing roles of linear drive and non-linear reduction of the turbulent fluxes. Possibilities to use the models to interpret TJ-II plasmas are discussed. (Author) 62 refs.

  20. A fast iterative recursive least squares algorithm for Wiener model identification of highly nonlinear systems.

    Science.gov (United States)

    Kazemi, Mahdi; Arefi, Mohammad Mehdi

    2016-12-15

    In this paper, an online identification algorithm is presented for nonlinear systems in the presence of output colored noise. The proposed method is based on extended recursive least squares (ERLS) algorithm, where the identified system is in polynomial Wiener form. To this end, an unknown intermediate signal is estimated by using an inner iterative algorithm. The iterative recursive algorithm adaptively modifies the vector of parameters of the presented Wiener model when the system parameters vary. In addition, to increase the robustness of the proposed method against variations, a robust RLS algorithm is applied to the model. Simulation results are provided to show the effectiveness of the proposed approach. Results confirm that the proposed method has fast convergence rate with robust characteristics, which increases the efficiency of the proposed model and identification approach. For instance, the FIT criterion will be achieved 92% in CSTR process where about 400 data is used.

  1. Eddy Current Modeling and Measuring in Fast-Pulsed Resistive Magnets

    CERN Document Server

    Arpaia, P; Gollucio, G; Montenero, G

    2010-01-01

    A method for modeling and measuring electromagnetic transients due to eddy currents in fast-pulsed resistive magnets is proposed. In particular, an equivalent-circuit model and a method for time-domain measurements of eddy currents are presented. The measurements are needed for an accurate control of the magnetic field quality to ensure adequate stability and performance of the particle beam in particle accelerators in dynamic conditions (field ramps up to about 700 T/s). In the second part, the results of experiments for model definition, identification, and validation are discussed. The tests were carried out on a quadrupole of Linac4, a new linear particle accelerator under construction at CERN (European Organization for Nuclear Research).

  2. Mechanical model of the ultra-fast underwater trap of Utricularia

    CERN Document Server

    Joyeux, Marc; Marmottant, Philippe

    2011-01-01

    The underwater traps of the carnivorous plants of the Utricularia species catch their preys through the repetition of an "active slow deflation / passive fast suction" sequence. In this paper, we propose a mechanical model that describes both phases and strongly supports the hypothesis that the trap door acts as a flexible valve that buckles under the combined effects of pressure forces and the mechanical stimulation of trigger hairs, and not as a panel articulated on hinges. This model combines two different approaches, namely (i) the description of thin membranes as triangle meshes with strain and curvature energy, and (ii) the molecular dynamics approach, which consists in computing the time evolution of the position of each vertex of the mesh according to Langevin equations. The only free parameter in the expression of the elastic energy is the Young's modulus E of the membranes. The values for this parameter are unequivocally obtained by requiring that the trap model fires, like real traps, when the pres...

  3. Fast food diet with CCl4 micro-dose induced hepatic-fibrosis –a novel animal model

    Science.gov (United States)

    2014-01-01

    Background Non-alcoholic fatty liver disease (NAFLD) is defined as a spectrum of conditions ranging from hepatocellular steatosis to steatohepatitis and fibrosis, progressing to cirrhosis, which occur in the absence of excessive alcohol use. Several animal models capture aspects of NAFLD but are limited either in their representation of the disease stages or use for development of therapeutics due to the extended periods of time required to develop full histological features. Methods Here, we report the development of a novel rat model for NAFLD that addresses some of these limitations. We used a fast food diet (FFD) and a CCl4 micro dose (0.5 ml/kg B.wt) for 8 weeks in Wistar rats. Serological analyses, gene expression profiling and liver histology studies were conducted to investigate the development of steatosis, steatohepatitis and fibrosis in the FFD-CCl4 model when compared to the individual effects of a FFD or a micro dose of CCl4 in rats. Results The serum biochemical profile of the FFD-CCl4 model showed an increase in liver injury and fibrosis. This was also accompanied by a significant increase in liver triglycerides (TG), inflammation and oxidative stress. Importantly, we observed extensive fibrosis confirmed by: i) increased gene expression of fibrosis markers and, ii) moderate to severe collagen deposition seen as perisinusoidal and bridging fibrosis using H&E, Trichome and Sirius Red staining. Conclusions In summary, we find that the FFD-CCl4 rat model developed NAFLD histological features including, steatosis, inflammation and fibrosis in 8 weeks showing promise as a model that can be used to develop NAFLD therapeutics and liver anti-fibrotics. PMID:24884574

  4. Quantifying noise-induced stability of a cortical fast-spiking cell model with Kv3-channel-like current.

    Science.gov (United States)

    Tateno, T; Robinson, H P C

    2007-01-01

    Population oscillations in neural activity in the gamma (>30 Hz) and higher frequency ranges are found over wide areas of the mammalian cortex. Recently, in the somatosensory cortex, the details of neural connections formed by several types of GABAergic interneurons have become apparent, and they are believed to play a significant role in generating these oscillations through synaptic and gap-junctional interactions. However, little is known about the mechanism of how such oscillations are maintained stably by particular interneurons and by their local networks, in a noisy environment with abundant synaptic inputs. To obtain more insight into this, we studied a fast-spiking (FS)-cell model including Kv3-channel-like current, which is a distinctive feature of these cells, from the viewpoint of nonlinear dynamical systems. To examine the specific role of the Kv3-channel in determining oscillation properties, we analyzed basic properties of the FS-cell model, such as the bifurcation structure and phase resetting curves (PRCs). Furthermore, to quantitatively characterize the oscillation stability under noisy fluctuations mimicking small fast synaptic inputs, we applied a recently developed method from random dynamical system theory to estimate Lyapunov exponents, both for the original four-dimensional dynamics and for a reduced one-dimensional phase-equation on the circle. The results indicated that the presence of the Kv3-channel-like current helps to regulate the stability of noisy neural oscillations and a transient-period length to stochastic attractors.

  5. Concept of a Fast and Simple Atmospheric Radiative Transfer Model for Aerosol Retrieval

    Science.gov (United States)

    Seidel, Felix; Kokhanovsky, Alexander A.

    2010-05-01

    Radiative transfer modelling (RTM) is an indispensable tool for a number of applications, including astrophysics, climate studies and quantitative remote sensing. It simulates the attenuation of light through a translucent medium. Here, we look at the scattering and absorption of solar light on its way to the Earth's surface and back to space or back into a remote sensing instrument. RTM is regularly used in the framework of the so-called atmospheric correction to find properties of the surface. Further, RTM can be inverted to retrieve features of the atmosphere, such as the aerosol optical depth (AOD), for instance. Present-day RTM, such as 6S, MODTRAN, SHARM, RT3, SCIATRAN or RTMOM have errors of only a few percent, however they are rather slow and often not easy to use. We present here a concept for a fast and simple RTM model in the visible spectral range. It is using a blend of different existing RTM approaches with a special emphasis on fast approximative analytical equations and parametrizations. This concept may be helpful for efficient retrieval algorithms, which do not have to rely on the classic look-up-tables (LUT) approach. For example, it can be used to retrieve AOD without complex inversion procedures including multiple iterations. Naturally, there is always a trade-off between speed and modelling accuracy. The code can be run therefore in two different modes. The regular mode provides a reasonable ratio between speed and accuracy, while the optional mode is very fast but less accurate. The normal mode approximates the diffuse scattered light by calculating the first (single scattering) and second order of scattering according to the classical method of successive orders of scattering. The very fast mode calculates only the single scattering approximation, which does not need any slow numerical integration procedure, and uses a simple correction factor to account for multiple scattering. This factor is a parametrization of MODTRAN results, which

  6. Development of Fast Response In-situ Sensors for Simultaneous Measurements of Seawater Carbon Dioxide Parameters

    Science.gov (United States)

    Wang, A. Z.; Sonnichsen, F. N.; Chu, S. N.; Bradley, A. M.; Hoering, K.

    2016-02-01

    The marine CO2 (inorganic carbon) system is characterized by four primary parameters - total dissolved inorganic carbon (DIC), total alkalinity (TA), partial pressure of CO2 (pCO2), and pH. These parameters are central to the study of the marine carbon cycle and ocean acidification. Simultaneous measurements of two of the four CO2 parameters are required to fully resolve the seawater CO2 system, and DIC is one of the preferred parameters. A self-calibrating, in-situ sensor, Channelized Optical System (CHANOS), has recently been developed to provide simultaneous measurements of both DIC and pH, resolving carbonate chemistry with a single system. CHANOS is among the first to achieve simultaneous, in-situ measurements of a desired pair of CO2 parameters. DIC and pH channels both use flow-through, spectrophotometric methods to detect relative absorbances of the acid and base forms of a pH-sensitive indicator. The precision of CHANOS in laboratory and in-situ tests are ±0.002 and ±3.0 µmol kg-1 for pH and DIC, respectively. In-situ comparison with bottle sampling and analyses indicate that the accuracies for pH and DIC are ±0.004 and ±5.0 µmol kg-1, respectively. It has been demonstrated that CHANOS can make in-situ, climatology-quality measurements to resolve the CO2 system in dynamic aquatic environments. To further improve response time of the sensor, especially for DIC measurements, a new generation of CHANOS-DIC is under development. The new system adapts the recently developed spectrophotometric DIC method to achieve flow-through CO2 equilibration between an acidified sample and an indicator solution with a response time as fast as 22s. Continuous measurements are also achievable. Because of the fast response of CHANOS measurements, it is versatile and suitable for deployments on both fixed (e.g. buoys) and mobile (e.g., AUV, ROV, and profilers) platforms.

  7. Development of the Fast Ionization Gauge in a Strong Magnetic Field

    Institute of Scientific and Technical Information of China (English)

    WANGMingxu; LIBo; YANGZhigang; ZHANGNianman; WUJihong; YANDonghai

    2002-01-01

    The neutral gas pressure near plasma or divertor plates are very important for the plasma-wall interaction, which determines the operating mode of divertor and confining performances of plasma in tokamaks. A fast ionization gauge (fast gauge) is designed for this purpose in the HL-2A tokamak.

  8. Electromagnetic Modeling of a Fast Traveling-Wave Beam Chopper for the SNS Project.

    Science.gov (United States)

    Kurennoy, Sergey

    1998-04-01

    High current and severe restrictions on beam losses, below 1 nA/m, in the designed linac for the Spallation Neutron Source (SNS) require clean and fast --- with the rise time from 2% to 98% less than 2.5 ns --- beam chopping in its front end, at the beam energy 2.5 MeV. The development of new traveling-wave deflecting current structures, based on meander lines, is discussed. Three-dimensional time-domain computer simulations are used to study transient effects in the chopper and to optimize its design.

  9. a Fast Method for Measuring the Similarity Between 3d Model and 3d Point Cloud

    Science.gov (United States)

    Zhang, Zongliang; Li, Jonathan; Li, Xin; Lin, Yangbin; Zhang, Shanxin; Wang, Cheng

    2016-06-01

    This paper proposes a fast method for measuring the partial Similarity between 3D Model and 3D point Cloud (SimMC). It is crucial to measure SimMC for many point cloud-related applications such as 3D object retrieval and inverse procedural modelling. In our proposed method, the surface area of model and the Distance from Model to point Cloud (DistMC) are exploited as measurements to calculate SimMC. Here, DistMC is defined as the weighted distance of the distances between points sampled from model and point cloud. Similarly, Distance from point Cloud to Model (DistCM) is defined as the average distance of the distances between points in point cloud and model. In order to reduce huge computational burdens brought by calculation of DistCM in some traditional methods, we define SimMC as the ratio of weighted surface area of model to DistMC. Compared to those traditional SimMC measuring methods that are only able to measure global similarity, our method is capable of measuring partial similarity by employing distance-weighted strategy. Moreover, our method is able to be faster than other partial similarity assessment methods. We demonstrate the superiority of our method both on synthetic data and laser scanning data.

  10. Development of a fast ELISA for the specific detection of both leucomalachite green and malachite green

    Science.gov (United States)

    Jiang, Yousheng; Chen, Li; Hu, Kun; Yu, Wenjuan; Yang, Xianle; Lu, Liqun

    2015-04-01

    Malachite green (MG), a dye, is an antifungal agent that has been used to treat and prevent fish diseases. It is metabolized into reduced leucomalachite green forms (LMG) that may reside in fish muscles for a long period, thus being harmful to human health. The aim of this study was to develop a competitive and direct enzyme-linked immunosorbent assay (ELISA) to detect MG and LMG specifically. The monoclonal antibody (mAb) to LMG was generated using a hybridoma technique. The obtained mAb showed good cross-reactivity (CR) to malachite green (MG), but not to crystal violet (CV) and Brilliant Green (BG). The mAb was used to develop a fast detecting ELISA of MG and LMG in fish. By introducing the conjugation LMG-HRP, the detection capability was 0.37 ng mL-1 for MG and LMG. The mean recovery from spiked grass carp tissues ranged from 76.2% to 82.9% and the coefficients of variation varied between 1.8% and 7.5%. The stable and efficient monoclonal cell line obtained is a sustainable source of sensitive and specific antibody to MG and LMG.

  11. Space Flight Cable Model Development

    Science.gov (United States)

    Spak, Kaitlin

    2013-01-01

    This work concentrates the modeling efforts presented in last year's VSGC conference paper, "Model Development for Cable-Harnessed Beams." The focus is narrowed to modeling of space-flight cables only, as a reliable damped cable model is not yet readily available and is necessary to continue modeling cable-harnessed space structures. New experimental data is presented, eliminating the low-frequency noise that plagued the first year's efforts. The distributed transfer function method is applied to a single section of space flight cable for Euler-Bernoulli and shear beams. The work presented here will be developed into a damped cable model that can be incorporated into an interconnected beam-cable system. The overall goal of this work is to accurately predict natural frequencies and modal damping ratios for cabled space structures.

  12. Perioperative role development: evaluating a fast-track approach to advanced scrub and/or dual role practitioner training.

    Science.gov (United States)

    Timpany, Michaela D; McAleavy, Janet

    2010-01-01

    This report describes the service evaluation of a newly developed fast-track advanced scrub practitioner (ASP)/dual role training programme. The evaluation examines whether the introduction of new policies and training based on risk assessment have strengthened quality assurance measures and controls which aim to ensure that staff work safely within their scope of practice. A further aim is to establish if the fast-track route is adequately meeting the training and development needs of staff within the organisation and supporting service requirements.

  13. Geosynchronous magnetic field responses to fast solar wind dynamic pressure enhancements: MHD field model

    Directory of Open Access Journals (Sweden)

    T. R. Sun

    2012-08-01

    Full Text Available We performed global MHD simulations of the geosynchronous magnetic field in response to fast solar wind dynamic pressure (Pd enhancements. Taking three Pd enhancement events in 2000 as examples, we found that the main features of the total field B and the dominant component Bz can be efficiently predicted by the MHD model. The predicted B and Bz varies with local time, with the highest level near noon and a slightly lower level around mid-night. However, it is more challenging to accurately predict the responses of the smaller component at the geosynchronous orbit (i.e., Bx and By. In contrast, the limitations of T01 model in predicting responses to fast Pd enhancements are presented.

  14. OPUS-Rota: a fast and accurate method for side-chain modeling.

    Science.gov (United States)

    Lu, Mingyang; Dousis, Athanasios D; Ma, Jianpeng

    2008-09-01

    In this paper, we introduce a fast and accurate side-chain modeling method, named OPUS-Rota. In a benchmark comparison with the methods SCWRL, NCN, LGA, SPRUCE, Rosetta, and SCAP, OPUS-Rota is shown to be much faster than all the methods except SCWRL, which is comparably fast. In terms of overall chi (1) and chi (1+2) accuracies, however, OPUS-Rota is 5.4 and 8.8 percentage points better, respectively, than SCWRL. Compared with NCN, which has the best accuracy in the literature, OPUS-Rota is 1.6 percentage points better for overall chi (1+2) but 0.3 percentage points weaker for overall chi (1). Hence, our algorithm is much more accurate than SCWRL with similar execution speed, and it has accuracy comparable to or better than the most accurate methods in the literature, but with a runtime that is one or two orders of magnitude shorter. In addition, OPUS-Rota consistently outperforms SCWRL on the Wallner and Elofsson homology-modeling benchmark set when the sequence identity is greater than 40%. We hope that OPUS-Rota will contribute to high-accuracy structure refinement, and the computer program is freely available for academic users.

  15. Development of Preliminary HT9 Cladding Tube for Sodium-cooled Fast Reactor (SFR)

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jun Hwan; Baek, Jong Hyuk; Heo, Hyeong Min; Park, Sang Gyu; Kim, Sung Ho; Lee, Chan Bock [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-05-15

    To achieve manufacturing technology of the fuel cladding tube in order to keep pace with the predetermined schedule in developing SFR fuel, KAERI has launched in developing fuel cladding tube in cooperation with a domestic steelmaking company. After fabricating medium-sized 1.1 ton HT9 ingot, followed by the multiple processes of hot and cold working, preliminary samples of HT9 seamless cladding tube having 7.4mm in outer diameter, 0.56mm in thickness, and 3m in length were fabricated. The objective of this study is to summarize the brief development status of the HT9 cladding tubes. Mechanical properties like axial tension, biaxial burst, pressurized creep and sodium compatibility of the cladding tubes were carried out to set up the performance evaluation technology to test the prototype FMS cladding tube which is going to be manufactured in next stage. As a part of developing fuel cladding for the Sodium-cooled Fast Reactor (SFR), preliminary HT9 cladding tube was fabricated in cooperation with a domestic steelmaking company. Microstructure as well as mechanical tests like axial tensile test, biaxial burst test, and pressurized creep test of the fuel cladding were carried out. Performance of the domestic HT9 tube was revealed to be similar in the previously fabricated foreign HT9 tube. Further prototype FMS cladding tube is going to be manufactured in next year based on this experience. Various test items like mechanical test, sodium compatibility test, microstructural analysis, basic property, cladding performance under transient situation, and performance under ion and neutron irradiation are going be performed in the future to set up the relevant technology for the licensing of the SFR cladding tube.

  16. Fabrication technological development of the oxide dispersion strengthened alloy MA957 for fast reactor applications

    Energy Technology Data Exchange (ETDEWEB)

    ML Hamilton; DS Gelles; RJ Lobsinger; GD Johnson; WF Brown; MM Paxton; RJ Puigh; CR Eiholzer; C Martinez; MA Blotter

    2000-03-27

    A significant amount of effort has been devoted to determining the properties and understanding the behavior of the alloy MA957 to define its potential usefulness as a cladding material, in the fast breeder reactor program. The numerous characterization and fabrication studies that were conducted are documented in this report. The alloy is a ferritic stainless steel developed by International Nickel Company specifically for structural reactor applications. It is strengthened by a very fine, uniformly distributed yttria dispersoid. Its fabrication involves a mechanical alloying process and subsequent extrusion, which ultimately results in a highly elongated grain structure. While the presence of the dispersoid produces a material with excellent strength, the body centered cubic structure inherent to the material coupled with the high aspect ratio that results from processing operations produces some difficulties with ductility. The alloy is very sensitive to variations in a number of processing parameters, and if the high strength is once lost during fabrication, it cannot be recovered. The microstructural evolution of the alloy under irradiation falls into two regimes. Below about 550 C, dislocation development, {alpha}{prime} precipitation and void evolution in the matrix are observed, while above about 550 C damage appears to be restricted to cavity formation within oxide particles. The thermal expansion of the alloy is very similar to that of HT9 up to the temperature where HT9 undergoes a phase transition to austenitic. Pulse magnetic welding of end caps onto MA957 tubing can be accomplished in a manner similar to that in which it is performed on HT9, although the welding parameters appear to be very sensitive to variations in the tubing that result from small changes in fabrication conditions. The tensile and stress rupture behavior of the alloy are acceptable in the unirradiated condition, being comparable to HT9 below about 700 C and exceeding those of HT9

  17. Robust Modeling of Low-Cost MEMS Sensor Errors in Mobile Devices Using Fast Orthogonal Search

    Directory of Open Access Journals (Sweden)

    M. Tamazin

    2013-01-01

    Full Text Available Accessibility to inertial navigation systems (INS has been severely limited by cost in the past. The introduction of low-cost microelectromechanical system-based INS to be integrated with GPS in order to provide a reliable positioning solution has provided more wide spread use in mobile devices. The random errors of the MEMS inertial sensors may deteriorate the overall system accuracy in mobile devices. These errors are modeled stochastically and are included in the error model of the estimated techniques used such as Kalman filter or Particle filter. First-order Gauss-Markov model is usually used to describe the stochastic nature of these errors. However, if the autocorrelation sequences of these random components are examined, it can be determined that first-order Gauss-Markov model is not adequate to describe such stochastic behavior. A robust modeling technique based on fast orthogonal search is introduced to remove MEMS-based inertial sensor errors inside mobile devices that are used for several location-based services. The proposed method is applied to MEMS-based gyroscopes and accelerometers. Results show that the proposed method models low-cost MEMS sensors errors with no need for denoising techniques and using smaller model order and less computation, outperforming traditional methods by two orders of magnitude.

  18. Modeling the Zeeman effect in high altitude SSMIS channels for numerical weather prediction profiles: comparing a fast model and a line-by-line model

    Directory of Open Access Journals (Sweden)

    R. Larsson

    2015-10-01

    Full Text Available We present a comparison of a reference and a fast radiative transfer model using numerical weather prediction profiles for the Zeeman-affected high altitude Special Sensor Microwave Imager/Sounder channels 19–22. We find that the models agree well for channels 21 and 22 compared to the channels' system noise temperatures (1.9 and 1.3 K, respectively and the expected profile errors at the affected altitudes (estimated to be around 5 K. For channel 22 there is a 0.5 K average difference between the models, with a standard deviation of 0.24 K for the full set of atmospheric profiles. Same channel, there is 1.2 K in average between the fast model and the sensor measurement, with 1.4 K standard deviation. For channel 21 there is a 0.9 K average difference between the models, with a standard deviation of 0.56 K. Same channel, there is 1.3 K in average between the fast model and the sensor measurement, with 2.4 K standard deviation. We consider the relatively small model differences as a validation of the fast Zeeman effect scheme for these channels. Both channels 19 and 20 have smaller average differences between the models (at below 0.2 K and smaller standard deviations (at below 0.4 K when both models use a two-dimensional magnetic field profile. However, when the reference model is switched to using a full three-dimensional magnetic field profile, the standard deviation to the fast model is increased to almost 2 K due to viewing geometry dependencies causing up to ± 7 K differences near the equator. The average differences between the two models remain small despite changing magnetic field configurations. We are unable to compare channels 19 and 20 to sensor measurements due to limited altitude range of the numerical weather prediction profiles. We recommended that numerical weather prediction software using the fast model takes the available fast Zeeman scheme into account for data assimilation of the affected sensor channels to better

  19. Development of a Stair-Step Multifrequency Synchronized Excitation Signal for Fast Bioimpedance Spectroscopy

    Directory of Open Access Journals (Sweden)

    Yuxiang Yang

    2014-01-01

    Full Text Available Wideband excitation signal with finite prominent harmonic components is desirable for fast bioimpedance spectroscopy (BIS measurements. This work introduces a simple method to synthesize and realize a type of periodical stair-step multifrequency synchronized (MFS signal. The Fourier series analysis shows that the p-order MFS signal f(p,t has constant 81.06% energy distributed equally on its p  2nth primary harmonics. The synthesis principle is described firstly and then two examples of the 4-order and 5-order MFS signals, f(4,t and f(5,t, are synthesized. The method to implement the MFS waveform based on a field-programmable gate array (FPGA and a digital to analog converter (DAC is also presented. Both the number and the frequencies of the expected primary harmonics can be adjusted as needed. An impedance measurement experiment on a RC three-element equivalent model is performed, and results show acceptable precision, which validates the feasibility of the MFS excitation.

  20. Development of a Stair-Step Multifrequency Synchronized Excitation Signal for Fast Bioimpedance Spectroscopy

    Science.gov (United States)

    Bian, He; Du, Fangling; Sun, Qiang

    2014-01-01

    Wideband excitation signal with finite prominent harmonic components is desirable for fast bioimpedance spectroscopy (BIS) measurements. This work introduces a simple method to synthesize and realize a type of periodical stair-step multifrequency synchronized (MFS) signal. The Fourier series analysis shows that the p-order MFS signal f(p, t) has constant 81.06% energy distributed equally on its p  2nth primary harmonics. The synthesis principle is described firstly and then two examples of the 4-order and 5-order MFS signals, f(4, t) and f(5, t), are synthesized. The method to implement the MFS waveform based on a field-programmable gate array (FPGA) and a digital to analog converter (DAC) is also presented. Both the number and the frequencies of the expected primary harmonics can be adjusted as needed. An impedance measurement experiment on a RC three-element equivalent model is performed, and results show acceptable precision, which validates the feasibility of the MFS excitation. PMID:24701563

  1. Electromagnetic modeling of an eddy-current position sensor for use in a fast reactor

    Science.gov (United States)

    Wu, Tao; Bowler, John R.

    2017-02-01

    In this article, we proposed a novel theoretical electromagnetic model of an eddy current probe used as a position sensor with respect to a tube in a fast reactor under standby conditions. In these circumstances the coil position cannot be guided by optical aids but electromagnetic sensing can be used. Initially, we derived analytical expressions for the quasi-static time-harmonic electromagnetic field of a circular current filament via the transverse magnetic potential expressed in terms of a single layer potential. This is then used to deduce the field of a circular sensor coil near a conductive tube, the axis of the coil having an arbitrary direction with respect to that of the tube. The fields for an external coil have been determined and can be used to deduce coil impedance variations with frequency, location and orientation. The model predictions can be used to guide the probe to a desire position with respect to the tube.

  2. Fast and accurate calculations for cumulative first-passage time distributions in Wiener diffusion models

    DEFF Research Database (Denmark)

    Blurton, Steven Paul; Kesselmeier, M.; Gondan, Matthias

    2012-01-01

    related work on the density of first-passage times [Navarro, D.J., Fuss, I.G. (2009). Fast and accurate calculations for first-passage times in Wiener diffusion models. Journal of Mathematical Psychology, 53, 222-230]. Two representations exist for the distribution, both including infinite series. We......We propose an improved method for calculating the cumulative first-passage time distribution in Wiener diffusion models with two absorbing barriers. This distribution function is frequently used to describe responses and error probabilities in choice reaction time tasks. The present work extends...... derive upper bounds for the approximation error resulting from finite truncation of the series, and we determine the number of iterations required to limit the error below a pre-specified tolerance. For a given set of parameters, the representation can then be chosen which requires the least...

  3. Code assessment and modelling for Design Basis Accident Analysis of the European sodium fast reactor design. Part I: System description, modelling and benchmarking

    Energy Technology Data Exchange (ETDEWEB)

    Lázaro, A., E-mail: aurelio.lazaro-chueca@ec.europa.eu [JRC-IET European Commission—Westerduinweg 3, PO Box-2, 1755 ZG Petten (Netherlands); UPV—Universidad Politecnica de Valencia, Cami de vera s/n-46002, Valencia (Spain); Ammirabile, L. [JRC-IET European Commission—Westerduinweg 3, PO Box-2, 1755 ZG Petten (Netherlands); Bandini, G. [ENEA, Via Martiri di Monte Sole 4, 40129 Bologna (Italy); Darmet, G.; Massara, S. [EDF, 1 avenue du Général de Gaulle, 92141 Clamart (France); Dufour, Ph.; Tosello, A. [CEA, St Paul lez Durance, 13108 Cadarache (France); Gallego, E.; Jimenez, G. [UPM, José Gutiérrez Abascal, 2-28006 Madrid (Spain); Mikityuk, K. [PSI—Paul Scherrer Institut, 5232 Villigen Switzerland (Switzerland); Schikorr, M.; Bubelis, E.; Ponomarev, A.; Kruessmann, R. [KIT—Institute for Neutron Physics and Reactor Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen Germany (Germany); Stempniewicz, M. [NRG, Utrechtseweg 310, PO Box 9034 6800 ES, Arnhem (Netherlands)

    2014-01-15

    Highlights: • Ten system-code models of the ESFR were developed in the frame of the CP-ESFR project. • Eight different thermohydraulic system codes adapted to sodium fast reactor's technology. • Benchmarking exercise settled to check the consistency of the calculations. • Upgraded system codes able to simulate the reactivity feedback and key safety parameters. -- Abstract: The new reactor concepts proposed in the Generation IV International Forum (GIF) are conceived to improve the use of natural resources, reduce the amount of high-level radioactive waste and excel in their reliability and safe operation. Among these novel designs sodium fast reactors (SFRs) stand out due to their technological feasibility as demonstrated in several countries during the last decades. As part of the contribution of EURATOM to GIF the CP-ESFR is a collaborative project with the objective, among others, to perform extensive analysis on safety issues involving renewed SFR demonstrator designs. The verification of computational tools able to simulate the plant behaviour under postulated accidental conditions by code-to-code comparison was identified as a key point to ensure reactor safety. In this line, several organizations employed coupled neutronic and thermal-hydraulic system codes able to simulate complex and specific phenomena involving multi-physics studies adapted to this particular fast reactor technology. In the “Introduction” of this paper the framework of this study is discussed, the second section describes the envisaged plant design and the commonly agreed upon modelling guidelines. The third section presents a comparative analysis of the calculations performed by each organisation applying their models and codes to a common agreed transient with the objective to harmonize the models as well as validating the implementation of all relevant physical phenomena in the different system codes.

  4. Advanced laser particle accelerator development at LANL: from fast ignition to radiation oncology

    Energy Technology Data Exchange (ETDEWEB)

    Flippo, Kirk A [Los Alamos National Laboratory; Gaillard, Sandrine A [Los Alamos National Laboratory; Offermann, D T [Los Alamos National Laboratory; Cobble, J A [Los Alamos National Laboratory; Schmitt, M J [Los Alamos National Laboratory; Gautier, D C [Los Alamos National Laboratory; Kwan, T J T [Los Alamos National Laboratory; Montgomery, D S [Los Alamos National Laboratory; Kluge, Thomas [FZD-GERMANY; Bussmann, Micheal [FZD-GERMANY; Bartal, T [UCSD; Beg, F N [UCSD; Gall, B [UNIV OF MISSOURI; Geissel, M [SNL; Korgan, G [NANOLABZ; Kovaleski, S [UNIV OF MISSOURI; Lockard, T [UNIV OF NEVADA; Malekos, S [NANOLABZ; Schollmeier, M [SNL; Sentoku, Y [UNIV OF NEVADA; Cowan, T E [FZD-GERMANY

    2010-01-01

    Laser-plasma accelerated ion and electron beam sources are an emerging field with vast prospects, and promise many superior applications in a variety of fields such as hadron cancer therapy, compact radioisotope generation, table-top nuclear physics, laboratory astrophysics, nuclear forensics, waste transmutation, SN M detection, and inertial fusion energy. LANL is engaged in several projects seeking to develop compact high current and high energy ion and electron sources. We are especially interested in two specific applications: ion fast ignition/capsule perturbation and radiation oncology in conjunction with our partners at the ForschungsZentrum Dresden-Rossendorf (FZD). Laser-to-beam conversion efficiencies of over 10% are needed for practical applications, and we have already shown inherent etliciencies of >5% from flat foils, on Trident using only a 5th of the intensity and energy of the Nova Petawatt. With clever target designs, like structured curved cone targets, we have also been able to achieve major ion energy gains, leading to the highest energy laser-accelerated proton beams in the world. These new target designs promise to help usher in the next generation of particle sources realizing the potential of laser-accelerated beams.

  5. Fast analysis of glibenclamide and its impurities: quality by design framework in capillary electrophoresis method development.

    Science.gov (United States)

    Furlanetto, Sandra; Orlandini, Serena; Pasquini, Benedetta; Caprini, Claudia; Mura, Paola; Pinzauti, Sergio

    2015-10-01

    A fast capillary zone electrophoresis method for the simultaneous analysis of glibenclamide and its impurities (I(A) and I(B)) in pharmaceutical dosage forms was fully developed within a quality by design framework. Critical quality attributes were represented by I(A) peak efficiency, critical resolution between glibenclamide and I(B), and analysis time. Experimental design was efficiently used for rapid and systematic method optimization. A 3(5)//16 symmetric screening matrix was chosen for investigation of the five selected critical process parameters throughout the knowledge space, and the results obtained were the basis for the planning of the subsequent response surface study. A Box-Behnken design for three factors allowed the contour plots to be drawn and the design space to be identified by introduction of the concept of probability. The design space corresponded to the multidimensional region where all the critical quality attributes reached the desired values with a degree of probability π ≥ 90%. Under the selected working conditions, the full separation of the analytes was obtained in less than 2 min. A full factorial design simultaneously allowed the design space to be validated and method robustness to be tested. A control strategy was finally implemented by means of a system suitability test. The method was fully validated and was applied to real samples of glibenclamide tablets.

  6. Development of a fast, lean and agile direct pelletization process using experimental design techniques.

    Science.gov (United States)

    Politis, Stavros N; Rekkas, Dimitrios M

    2017-04-01

    A novel hot melt direct pelletization method was developed, characterized and optimized, using statistical thinking and experimental design tools. Mixtures of carnauba wax (CW) and HPMC K100M were spheronized using melted gelucire 50-13 as a binding material (BM). Experimentation was performed sequentially; a fractional factorial design was set up initially to screen the factors affecting the process, namely spray rate, quantity of BM, rotor speed, type of rotor disk, lubricant-glidant presence, additional spheronization time, powder feeding rate and quantity. From the eight factors assessed, three were further studied during process optimization (spray rate, quantity of BM and powder feeding rate), at different ratios of the solid mixture of CW and HPMC K100M. The study demonstrated that the novel hot melt process is fast, efficient, reproducible and predictable. Therefore, it can be adopted in a lean and agile manufacturing setting for the production of flexible pellet dosage forms with various release rates easily customized between immediate and modified delivery.

  7. Simulation tools and new developments of the molten salt fast reactor

    Energy Technology Data Exchange (ETDEWEB)

    Heuer, D.; Merle-Lucotte, E.; Allibert, M.; Doligez, X.; Ghetta, V. [LPSC-IN2P3-CNRS/UJF, 38 - Grenoble (France)

    2010-11-15

    In the MSFR (Molten Salt Fast Reactor), the liquid fuel processing is part of the reactor where a small side stream of the molten salt is processed for fission product removal and then returned to the reactor. Because of this design characteristic, the MSFR can thus operate with a widely varying fuel composition. Our reactor's studies of the MSFR concept rely on numerical simulations making use of the MCNP neutron transport code coupled with a code for Bateman's equations computing the population of any nucleus inside any part of the reactor at any moment. The classical Bateman's equations have been modified by adding 2 terms representing the reprocessing capacities and an online addition. We have thus coupled neutronic and reprocessing simulation codes in a numerical tool used to calculate the extraction efficiencies of fission products, their location in the whole system and radioprotection issues. The very preliminary results show the potential of the neutronic-reprocessing coupling we have developed. We also show that these studies are limited by the uncertainties on the design and the knowledge of the chemical reprocessing processes. (A.C.)

  8. Advanced Laser Particle Accelerator Development at LANL: From Fast Ignition to Radiation Oncology

    Science.gov (United States)

    Flippo, K. A.; Gaillard, S. A.; Kluge, T.; Bussmann, M.; Offermann, D. T.; Cobble, J. A.; Schmitt, M. J.; Bartal, T.; Beg, F. N.; Cowan, T. E.; Gall, B.; Gautier, D. C.; Geissel, M.; Kwan, T. J.; Korgan, G.; Kovaleski, S.; Lockard, T.; Malekos, S.; Montgomery, D. S.; Schollmeier, M.; Sentoku, Y.

    2010-11-01

    Laser-plasma accelerated ion and electron beam sources are an emerging field with vast prospects, and promise many superior applications in a variety of fields such as hadron cancer therapy, compact radioisotope generation, table-top nuclear physics, laboratory astrophysics, nuclear forensics, waste transmutation, Special Nuclear Material (SNM) detection, and inertial fusion energy. LANL is engaged in several projects seeking to develop compact high-current and high-energy ion and electron sources. We are especially interested in two specific applications: ion fast ignition/capsule perturbation and radiation oncology. Laser-to-beam conversion efficiencies of over 10% are needed for practical applications, and we have already shown inherent efficiencies of >5% from flat foils, on Trident using only a 5th of the intensity [1] and energy of the Nova Petawatt laser [2]. With clever target designs, like structured curved cone targets, we have also been able to achieve major ion energy gains, leading to the highest energy laser-accelerated proton beams in the world [3]. These new target designs promise to help usher in the next generation of particle sources realizing the potential of laser-accelerated beams.

  9. Development of fast heating electron beam annealing setup for ultra high vacuum chamber

    Science.gov (United States)

    Das, Sadhan Chandra; Majumdar, Abhijit; Katiyal, Sumant; Shripathi, T.; Hippler, R.

    2014-02-01

    We report the design and development of a simple, electrically low powered and fast heating versatile electron beam annealing setup (up to 1000 °C) working with ultra high vacuum (UHV) chamber for annealing thin films and multilayer structures. The important features of the system are constant temperature control in UHV conditions for the temperature range from room temperature to 1000 °C with sufficient power of 330 W, at constant vacuum during annealing treatment. It takes approximately 6 min to reach 1000 °C from room temperature (˜10-6 mbar) and 45 min to cool down without any extra cooling. The annealing setup consists of a UHV chamber, sample holder, heating arrangement mounted on suitable UHV electrical feed-through and electronic control and feedback systems to control the temperature within ±1 °C of set value. The outside of the vacuum chamber is cooled by cold air of 20 °C of air conditioning machine used for the laboratory, so that chamber temperature does not go beyond 50 °C when target temperature is maximum. The probability of surface oxidation or surface contamination during annealing is examined by means of x-ray photoelectron spectroscopy of virgin Cu sample annealed at 1000 °C.

  10. Experimental Development and Demonstration of Ultrasonic Measurement Diagnostics for Sodium Fast Reactor Thermal-hydraulics

    Energy Technology Data Exchange (ETDEWEB)

    Tokuhiro, Akira; Jones, Byron

    2013-09-13

    This research project will address some of the principal technology issues related to sodium-cooled fast reactors (SFR), primarily the development and demonstration of ultrasonic measurement diagnostics linked to effective thermal convective sensing under normatl and off-normal conditions. Sodium is well-suited as a heat transfer medium for the SFR. However, because it is chemically reactive and optically opaque, it presents engineering accessibility constraints relative to operations and maintenance (O&M) and in-service inspection (ISI) technologies that are currently used for light water reactors. Thus, there are limited sensing options for conducting thermohydraulic measurements under normal conditions and off-normal events (maintenance, unanticipated events). Acoustic methods, primarily ultrasonics, are a key measurement technology with applications in non-destructive testing, component imaging, thermometry, and velocimetry. THis project would have yielded a better quantitative and qualitative understanding of the thermohydraulic condition of solium under varied flow conditions. THe scope of work will evaluate and demonstrate ultrasonic technologies and define instrumentation options for the SFR.

  11. Simple Attenauation Models of Metallic Cables Suitable for G.fast Frequencies

    Directory of Open Access Journals (Sweden)

    Pavel Lafata

    2015-01-01

    Full Text Available Recently, a new xDSL successor called G.fast, which can occupy frequencies up to 106 or 212~MHz, has been introduced in ITU-T G.9700 series of recommendations. Moreover, a new model of transmission characteristics suitable for various types of metallic cables has been designed and described as well. The model is based on 9 parameters specified for each type of metallic cable and can provide accurate estimations. However, its complexity together with the number of required parameters makes its practical application questionable, since the most important metallic cable characteristic, the attenuation, can be estimated using much simpler models. Therefore, two innovative attenuation models suitable for frequencies up to 250 MHz were designed and they will be introduced in this paper. The main motivation was to achieve an accurate approximation of attenuation character for various types of metallic cables, while maintaining low mathematical complexity and a number of necessary parameters. Both models were compared with attenuation characteristics measured for variety types of real metallic cables and also with other standard attenuation models. The results are included in this article as well.

  12. Dynamic performance of frictionless fast shutters for ITER: Numerical and analytical sensitivity study for the development of a test program

    Energy Technology Data Exchange (ETDEWEB)

    Panin, Anatoly, E-mail: a.panin@fz-juelich.de [Forschungszentrum Jülich GmbH, Institut für Energie- und Klimaforschung – Plasmaphysik, 52425 Jülich (Germany); Khovayko, Mikhail [St. Petersburg Polytechnic University, Mechanics and Control Processes Department, Computational Mechanics Laboratory, 195251 St. Petersburg (Russian Federation); Krasikov, Yury [Forschungszentrum Jülich GmbH, Institut für Energie- und Klimaforschung – Plasmaphysik, 52425 Jülich (Germany); Nemov, Alexander [St. Petersburg Polytechnic University, Mechanics and Control Processes Department, Computational Mechanics Laboratory, 195251 St. Petersburg (Russian Federation); Biel, Wolfgang; Mertens, Philippe; Neubauer, Olaf; Schrader, Michael [Forschungszentrum Jülich GmbH, Institut für Energie- und Klimaforschung – Plasmaphysik, 52425 Jülich (Germany)

    2015-10-15

    To prolong a lifetime of the ITER first diagnostic mirrors some protective shutters can be engaged. A concept of an elastic shutter that operates frictionless in vacuum has been studied at the Forschungszentrum Jülich, Germany. Under actuation two shutter arms (∼2 m long) bend laterally between two pairs of limiting bumpers thus shielding the optical aperture or opening it for measurements. To increase the shutter efficiency the transition time between its open and closed states can be minimized. This demands a fast shutter that operates in fractions of a second and exhibit essentially dynamic behavior, like impacts with the bumpers that cause the shutter arms’ bouncing and oscillations. The paper presents numerical studies of the shutter dynamic behavior using the explicit and implicit 3D FE transient structural modeling. Simple 1D analytical model was developed to predict the shutter impact kinetic energy that mostly determines its further dynamic response. The structure sensitivity to different parameters was studied and ways for its optimization were laid down. A parametric shutter mockup with easily changeable mechanical characteristics was manufactured. A test program aimed for further shutter optimization, basing on the analysis performed and engaging powerful capabilities of the parametric shutter mockup is discussed in the paper.

  13. Fast tracking ICT infrastructure requirements and design, based on Enterprise Reference Architecture and matching Reference Models

    DEFF Research Database (Denmark)

    Bernus, Peter; Baltrusch, Rob; Vesterager, Johan

    2002-01-01

    The Globemen Consortium has developed the virtual enterprise reference architecture and methodology (VERAM), based on GERAM and developed reference models for virtual enterprise management and joint mission delivery. The planned virtual enterprise capability includes the areas of sales and market......The Globemen Consortium has developed the virtual enterprise reference architecture and methodology (VERAM), based on GERAM and developed reference models for virtual enterprise management and joint mission delivery. The planned virtual enterprise capability includes the areas of sales...

  14. Asymptotic Analysis of a Loss Model with Trunk Reservation I: Trunks Reserved for Fast Traffic

    Directory of Open Access Journals (Sweden)

    John A. Morrison

    2008-01-01

    Full Text Available We consider a model for a single link in a circuit-switched network. The link has C circuits, and the input consists of offered calls of two types, that we call primary and secondary traffic. Of the C links, R are reserved for primary traffic. We assume that both traffic types arrive as Poisson arrival streams. Assuming that C is large and R=O(1, the arrival rate of primary traffic is O(C, while that of secondary traffic is smaller, of the order O(C. The holding times of the primary calls are assumed to be exponentially distributed with unit mean. Those of the secondary calls are exponentially distributed with a large mean, that is, O(C. Thus, the primary calls have fast arrivals and fast service, compared to the secondary calls. The loads for both traffic types are comparable (O(C, and we assume that the system is “critically loaded”; that is, the system's capacity is approximately equal to the total load. We analyze asymptotically the steady state probability that n1 (resp., n2 circuits are occupied by primary (resp., secondary calls. In particular, we obtain two-term asymptotic approximations to the blocking probabilities for both traffic types.

  15. Fast implementation for compressive recovery of highly accelerated cardiac cine MRI using the balanced sparse model.

    Science.gov (United States)

    Ting, Samuel T; Ahmad, Rizwan; Jin, Ning; Craft, Jason; Serafim da Silveira, Juliana; Xue, Hui; Simonetti, Orlando P

    2017-04-01

    Sparsity-promoting regularizers can enable stable recovery of highly undersampled magnetic resonance imaging (MRI), promising to improve the clinical utility of challenging applications. However, lengthy computation time limits the clinical use of these methods, especially for dynamic MRI with its large corpus of spatiotemporal data. Here, we present a holistic framework that utilizes the balanced sparse model for compressive sensing and parallel computing to reduce the computation time of cardiac MRI recovery methods. We propose a fast, iterative soft-thresholding method to solve the resulting ℓ1-regularized least squares problem. In addition, our approach utilizes a parallel computing environment that is fully integrated with the MRI acquisition software. The methodology is applied to two formulations of the multichannel MRI problem: image-based recovery and k-space-based recovery. Using measured MRI data, we show that, for a 224 × 144 image series with 48 frames, the proposed k-space-based approach achieves a mean reconstruction time of 2.35 min, a 24-fold improvement compared a reconstruction time of 55.5 min for the nonlinear conjugate gradient method, and the proposed image-based approach achieves a mean reconstruction time of 13.8 s. Our approach can be utilized to achieve fast reconstruction of large MRI datasets, thereby increasing the clinical utility of reconstruction techniques based on compressed sensing. Magn Reson Med 77:1505-1515, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  16. GIFFT: A Fast Solver for Modeling Sources in a Metamaterial Environment of Finite Size

    Energy Technology Data Exchange (ETDEWEB)

    Capolino, F; Basilio, L; Fasenfest, B J; Wilton, D R

    2006-01-23

    Due to the recent explosion of interest in studying the electromagnetic behavior of large (truncated) periodic structures such as phased arrays, frequency-selective surfaces, and metamaterials, there has been a renewed interest in efficiently modeling such structures. Since straightforward numerical analyses of large, finite structures (i.e., explicitly meshing and computing interactions between all mesh elements of the entire structure) involve significant memory storage and computation times, much effort is currently being expended on developing techniques that minimize the high demand on computer resources. One such technique that belongs to the class of fast solvers for large periodic structures is the GIFFT algorithm (Green's function interpolation and FFT), which is first discussed in [1]. This method is a modification of the adaptive integral method (AIM) [2], a technique based on the projection of subdomain basis functions onto a rectangular grid. Like the methods presented in [3]-[4], the GIFFT algorithm is an extension of the AIM method in that it uses basis-function projections onto a rectangular grid through Lagrange interpolating polynomials. The use of a rectangular grid results in a matrix-vector product that is convolutional in form and can thus be evaluated using FFTs. Although our method differs from [3]-[6] in various respects, the primary differences between the AIM approach [2] and the GIFFT method [1] is the latter's use of interpolation to represent the Green's function (GF) and its specialization to periodic structures by taking into account the reusability properties of matrices that arise from interactions between identical cell elements. The present work extends the GIFFT algorithm to allow for a complete numerical analysis of a periodic structure excited by dipole source, as shown in Fig 1. Although GIFFT [1] was originally developed to handle strictly periodic structures, the technique has now been extended to efficiently

  17. The Development of a 3D LADAR Simulator Based on a Fast Target Impulse Response Generation Approach

    Science.gov (United States)

    Al-Temeemy, Ali Adnan

    2017-09-01

    A new laser detection and ranging (LADAR) simulator has been developed, using MATLAB and its graphical user interface, to simulate direct detection time of flight LADAR systems, and to produce 3D simulated scanning images under a wide variety of conditions. This simulator models each stage from the laser source to data generation and can be considered as an efficient simulation tool to use when developing LADAR systems and their data processing algorithms. The novel approach proposed for this simulator is to generate the actual target impulse response. This approach is fast and able to deal with high scanning requirements without losing the fidelity that accompanies increments in speed. This leads to a more efficient LADAR simulator and opens up the possibility for simulating LADAR beam propagation more accurately by using a large number of laser footprint samples. The approach is to select only the parts of the target that lie in the laser beam angular field by mathematically deriving the required equations and calculating the target angular ranges. The performance of the new simulator has been evaluated under different scanning conditions, the results showing significant increments in processing speeds in comparison to conventional approaches, which are also used in this study as a point of comparison for the results. The results also show the simulator's ability to simulate phenomena related to the scanning process, for example, type of noise, scanning resolution and laser beam width.

  18. FastGGM: An Efficient Algorithm for the Inference of Gaussian Graphical Model in Biological Networks.

    Directory of Open Access Journals (Sweden)

    Ting Wang

    2016-02-01

    Full Text Available Biological networks provide additional information for the analysis of human diseases, beyond the traditional analysis that focuses on single variables. Gaussian graphical model (GGM, a probability model that characterizes the conditional dependence structure of a set of random variables by a graph, has wide applications in the analysis of biological networks, such as inferring interaction or comparing differential networks. However, existing approaches are either not statistically rigorous or are inefficient for high-dimensional data that include tens of thousands of variables for making inference. In this study, we propose an efficient algorithm to implement the estimation of GGM and obtain p-value and confidence interval for each edge in the graph, based on a recent proposal by Ren et al., 2015. Through simulation studies, we demonstrate that the algorithm is faster by several orders of magnitude than the current implemented algorithm for Ren et al. without losing any accuracy. Then, we apply our algorithm to two real data sets: transcriptomic data from a study of childhood asthma and proteomic data from a study of Alzheimer's disease. We estimate the global gene or protein interaction networks for the disease and healthy samples. The resulting networks reveal interesting interactions and the differential networks between cases and controls show functional relevance to the diseases. In conclusion, we provide a computationally fast algorithm to implement a statistically sound procedure for constructing Gaussian graphical model and making inference with high-dimensional biological data. The algorithm has been implemented in an R package named "FastGGM".

  19. Development of radiation tolerant monolithic active pixel sensors with fast column parallel read-out

    Science.gov (United States)

    Koziel, M.; Dorokhov, A.; Fontaine, J.-C.; De Masi, R.; Winter, M.

    2010-12-01

    Monolithic active pixel sensors (MAPS) [1] (Turchetta et al., 2001) are being developed at IPHC—Strasbourg to equip the EUDET telescope [2] (Haas, 2006) and vertex detectors for future high energy physics experiments, including the STAR upgrade at RHIC [3] (T.S. Collaboration, 2005) and the CBM experiment at FAIR/GSI [4] (Heuser, 2006). High granularity, low material budget and high read-out speed are systematically required for most applications, complemented, for some of them, with high radiation tolerance. A specific column-parallel architecture, implemented in the MIMOSA-22 sensor, was developed to achieve fast read-out MAPS. Previous studies of the front-end architecture integrated in this sensor, which includes in-pixel amplification, have shown that the fixed pattern noise increase consecutive to ionizing radiation can be controlled by means of a negative feedback [5] (Hu-Guo et al., 2008). However, an unexpected rise of the temporal noise was observed. A second version of this chip (MIMOSA-22bis) was produced in order to search for possible improvements of the radiation tolerance, regarding this type of noise. In this prototype, the feedback transistor was tuned in order to mitigate the sensitivity of the pixel to ionizing radiation. The performances of the pixels after irradiation were investigated for two types of feedback transistors: enclosed layout transistor (ELT) [6] (Snoeys et al., 2000) and "standard" transistor with either large or small transconductance. The noise performance of all test structures was studied in various conditions (expected in future experiments) regarding temperature, integration time and ionizing radiation dose. Test results are presented in this paper. Based on these observations, ideas for further improvement of the radiation tolerance of column parallel MAPS are derived.

  20. Kinetic modeling of a high power fast-axial-flow CO2 laser with computational fluid dynamics method

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A new computational fluid dynamics (CFD) method for the simulation of fast-axial-flow CO2 laser is developed.The model which is solved by CFD software uses a set of dynamic differential equations to describe the dynamic process in one discharge tube.The velocity,temperature,pressure and turbulence energy distributions in discharge passage are presented.There is a good agreement between the theoretical prediction and the experimental results.This result indicates that the parameters of the laser have significant effect on the flow distribution in the discharge passage.It is helpful to optimize the output of high power CO2 laser by mastering its kinetic characteristics.

  1. An approximation to the adaptive exponential integrate-and-fire neuron model allows fast and predictive fitting to physiological data

    Directory of Open Access Journals (Sweden)

    Loreen eHertäg

    2012-09-01

    Full Text Available For large-scale network simulations, it is often desirable to have computationally tractable, yet in a defined sense still physiologically valid neuron models. In particular, these models should be able to reproduce physiological measurements, ideally in a predictive sense, and under different input regimes in which neurons may operate in vivo. Here we present an approach to parameter estimation for a simple spiking neuron model mainly based on standard f-I curves obtained from in vitro recordings. Such recordings are routinely obtained in standard protocols and assess a neuron's response under a wide range of mean input currents. Our fitting procedure makes use of closed-form expressions for the firing rate derived from an approximation to the adaptive exponential integrate-and-fire (AdEx model. The resulting fitting process is simple and about two orders of magnitude faster compared to methods based on numerical integration of the differential equations. We probe this method on different cell types recorded from rodent prefrontal cortex. After fitting to the f-I current-clamp data, the model cells are tested on completely different sets of recordings obtained by fluctuating ('in-vivo-like' input currents. For a wide range of different input regimes, cell types, and cortical layers, the model could predict spike times on these test traces quite accurately within the bounds of physiological reliability, although no information from these distinct test sets was used for model fitting. Further analyses delineated some of the empirical factors constraining model fitting and the model's generalization performance. An even simpler adaptive LIF neuron was also examined in this context. Hence, we have developed a 'high-throughput' model fitting procedure which is simple and fast, with good prediction performance, and which relies only on firing rate information and standard physiological data widely and easily available.

  2. Fast evolving pair-instability supernova models: evolution, explosion, light curves

    Science.gov (United States)

    Kozyreva, Alexandra; Gilmer, Matthew; Hirschi, Raphael; Fröhlich, Carla; Blinnikov, Sergey; Wollaeger, Ryan T.; Noebauer, Ulrich M.; van Rossum, Daniel R.; Heger, Alexander; Even, Wesley P.; Waldman, Roni; Tolstov, Alexey; Chatzopoulos, Emmanouil; Sorokina, Elena

    2017-01-01

    With an increasing number of superluminous supernovae (SLSNe) discovered, the question of their origin remains open and causes heated debates in the supernova community. Currently, there are three proposed mechanisms for SLSNe: (1) pair-instability supernovae (PISNe), (2) magnetar-driven supernovae and (3) models in which the supernova ejecta interacts with a circumstellar material ejected before the explosion. Based on current observations of SLSNe, the PISN origin has been disfavoured for a number of reasons. Many PISN models provide overly broad light curves and too reddened spectra, because of massive ejecta and a high amount of nickel. In the current study, we re-examine PISN properties using progenitor models computed with the GENEC code. We calculate supernova explosions with FLASH and light-curve evolution with the radiation hydrodynamics code STELLA. We find that high-mass models (200 and 250 M⊙) at relatively high metallicity (Z = 0.001) do not retain hydrogen in the outer layers and produce relatively fast evolving PISNe Type I and might be suitable to explain some SLSNe. We also investigate uncertainties in light-curve modelling due to codes, opacities, the nickel-bubble effect and progenitor structure and composition.

  3. Fast evolving pair-instability supernova models: Evolution, explosion, light curves

    Science.gov (United States)

    Kozyreva, Alexandra; Gilmer, Matthew; Hirschi, Raphael; Fröhlich, Carla; Blinnikov, Sergey; Wollaeger, Ryan T.; Noebauer, Ulrich M.; van Rossum, Daniel R.; Heger, Alexander; Even, Wesley P.; Waldman, Roni; Tolstov, Alexey; Chatzopoulos, Emmanouil; Sorokina, Elena

    2016-10-01

    With an increasing number of superluminous supernovae (SLSNe) discovered the question of their origin remains open and causes heated debates in the supernova community. Currently, there are three proposed mechanisms for SLSNe: (1) pair-instability supernovae (PISN), (2) magnetar-driven supernovae, and (3) models in which the supernova ejecta interacts with a circumstellar material ejected before the explosion. Based on current observations of SLSNe, the PISN origin has been disfavoured for a number of reasons. Many PISN models provide overly broad light curves and too reddened spectra, because of massive ejecta and a high amount of nickel. In the current study we re-examine PISN properties using progenitor models computed with the GENEC code. We calculate supernova explosions with FLASH and light curve evolution with the radiation hydrodynamics code STELLA. We find that high-mass models (200 M⊙ and 250 M⊙) at relatively high metallicity (Z = 0.001) do not retain hydrogen in the outer layers and produce relatively fast evolving PISNe Type I and might be suitable to explain some SLSNe. We also investigate uncertainties in light curve modelling due to codes, opacities, the nickel-bubble effect and progenitor structure and composition.

  4. Indigenous development of a 2 kW RF-excited fast axial flow CO2 laser

    Indian Academy of Sciences (India)

    A K Biswas; M S Bhagat; L B Rana; A Verma; L M Kukreja

    2010-11-01

    RF-excited fast axial flow CO2 lasers in kilowatt regime are presently being used for various new scientific applications in addition to laser material processing because of its versatility and superior beam quality. We have indigenously developed a compact 2 kW RF-excited fast axial flow CO2 laser with moderate beam quality. In this paper the key design features of the laser and the associated high power capacitively coupled RF excitation technique are discussed in detail. Operational characteristics of this system are described along with the experimental findings.

  5. RTTOV-gb - Adapting the fast radiative transfer model RTTOV for the assimilation of ground-based microwave radiometer observations

    Science.gov (United States)

    De Angelis, Francesco; Cimini, Domenico; Hocking, James; Martinet, Pauline; Kneifel, Stefan

    2016-04-01

    The Planetary Boundary Layer (PBL) is the single most important under-sampled part of the atmosphere. According to the WMO Statement Of Guidance For Global Numerical Weather Prediction (NWP), temperature and humidity profiles (in cloudy areas) are among the four critical atmospheric variables not adequately measured in the PBL. Ground-based microwave radiometers (MWR) provide temperature and humidity profiles in both clear- and cloudy-sky conditions with high temporal resolution and low-to-moderate vertical resolution, with information mostly residing in the PBL. Ground-based MWR offer to bridge this observational gap by providing continuous temperature and humidity information in the PBL. The MWR data assimilation into NWP models may be particularly important in nowcasting and severe weather initiation. The assimilation of thermodynamic profiles retrieved from MWR data has been recently experimented, but a way to possibly increase the impact is to directly assimilate measured radiances instead of retrieved profiles. The assimilation of observed radiances in a variational scheme requires the following tools: (i) a fast radiative transfer (RT) model to compute the simulated radiances at MWR channels from the NWP model fields (ii) the partial derivatives (Jacobians) of the fast radiative transfer model with respect to control variables to optimize the distances of the atmospheric state from both the first guess and the observations. Such a RT model is available from the EUMETSAT NWPSAF (Numerical Weather Prediction Satellite Application Facility) and well accepted in the NWP community: RTTOV. This model was developed for nadir-viewing passive visible, infrared, and microwave satellite radiometers, spectrometers and interferometers. It has been modified to handle ground-based microwave radiometer observations. This version of RTTOV, called RTTOV-gb, provides the tools needed to exploit ground-based upward looking MWR brightness temperatures into NWP variational data

  6. Paradigm Innovation through the Strategic Collaboration between TORAY & UNIQLO : Evolution of A New Fast Fashion Business Model

    OpenAIRE

    Choi, Eugene K.

    2011-01-01

    The key purpose of this study is to examine the remarkable context within the evolution of the paradigm innovation in fashion product development, in the case of Japanese fashion apparel, UNIQLO, created by Fast Retailing Corp in 1998. The key theme hereby concerns innovation, and this perspective surely necessitates Fast Retailing's strategic collaboration with a Japanese new material and artificial textile powerhouse, TORAY: as TORAY's technological provision was an essential source for the...

  7. Development and validation of a micromethod for fast quantification of 5-n-alkylresorcinols in grains and whole grain products.

    Science.gov (United States)

    Sampietro, D A; Jimenez, C M; Belizán, M M; Vattuone, M A; Catalán, C A N

    2013-12-15

    A 96-well plate micromethod was developed to measure 5-n-alkylresorcinols (5nARs) in cereal grains and food derived products. The 5nARs reacted in alkaline alcoholic medium with Fast Blue RR ½ZnCl2 salt to yield coloured azo-derivatives. The highest sensitivity for 5nARs was obtained at 490 nm with 0.025% ethanolic Fast Blue RR and 5% K2CO3. This reaction showed good linearity for olivetol (0.05-0.20 μg). Contents of 5nARs determined in cereal grains and derived products by the new Fast Blue RR micromethod were highly correlated (R(2)=0.9944) with those obtained by a Fast Blue B method currently used. A Bland-Altman analysis indicated a small positive bias near to zero (R(2)=0.0401), suggesting that the methods can be interchangeably used. The new reaction is completed in 15 min and the coloured products are read within the 15 min after completion. The micromethod offers a fast analysis of 5nARs in cereal grains and derived products with low consumption of reagents and solvents.

  8. OSPREY Model Development Status Update

    Energy Technology Data Exchange (ETDEWEB)

    Veronica J Rutledge

    2014-04-01

    During the processing of used nuclear fuel, volatile radionuclides will be discharged to the atmosphere if no recovery processes are in place to limit their release. The volatile radionuclides of concern are 3H, 14C, 85Kr, and 129I. Methods are being developed, via adsorption and absorption unit operations, to capture these radionuclides. It is necessary to model these unit operations to aid in the evaluation of technologies and in the future development of an advanced used nuclear fuel processing plant. A collaboration between Fuel Cycle Research and Development Offgas Sigma Team member INL and a NEUP grant including ORNL, Syracuse University, and Georgia Institute of Technology has been formed to develop off gas models and support off gas research. Georgia Institute of Technology is developing fundamental level model to describe the equilibrium and kinetics of the adsorption process, which are to be integrated with OSPREY. This report discusses the progress made on expanding OSPREY to be multiple component and the integration of macroscale and microscale level models. Also included in this report is a brief OSPREY user guide.

  9. On-board B-ISDN fast packet switching architectures. Phase 2: Development. Proof-of-concept architecture definition report

    Science.gov (United States)

    Shyy, Dong-Jye; Redman, Wayne

    1993-01-01

    For the next-generation packet switched communications satellite system with onboard processing and spot-beam operation, a reliable onboard fast packet switch is essential to route packets from different uplink beams to different downlink beams. The rapid emergence of point-to-point services such as video distribution, and the large demand for video conference, distributed data processing, and network management makes the multicast function essential to a fast packet switch (FPS). The satellite's inherent broadcast features gives the satellite network an advantage over the terrestrial network in providing multicast services. This report evaluates alternate multicast FPS architectures for onboard baseband switching applications and selects a candidate for subsequent breadboard development. Architecture evaluation and selection will be based on the study performed in phase 1, 'Onboard B-ISDN Fast Packet Switching Architectures', and other switch architectures which have become commercially available as large scale integration (LSI) devices.

  10. Fast Blue RR—Siloxane Derivatized Materials Indicate Wound Infection Due to a Deep Blue Color Development

    Directory of Open Access Journals (Sweden)

    Doris Schiffer

    2015-09-01

    Full Text Available There is a strong need for simple and fast methods for wound infection determination. Myeloperoxidase, an immune system-derived enzyme was found to be a suitable biomarker for wound infection. Hence, alkoxysilane-derivatized Fast Blue RR was immobilized via simple hydrolytic polymerization. The resulting enzyme-responsive siloxane layers were incubated with myeloperoxidase, wound fluid or hemoglobin. The reaction was monitored via HPLC measurements and the color development quantified spectrophotometrically. Myeloperoxidase was indeed able to oxidize immobilized Fast Blue RR leading to a blue colored product. No conversion was detected in non-infected wound fluids. The visible color changes of these novel materials towards blue enable an easy distinction between infected and non-infected wound fluids.

  11. VARTM Model Development and Verification

    Science.gov (United States)

    Cano, Roberto J. (Technical Monitor); Dowling, Norman E.

    2004-01-01

    In this investigation, a comprehensive Vacuum Assisted Resin Transfer Molding (VARTM) process simulation model was developed and verified. The model incorporates resin flow through the preform, compaction and relaxation of the preform, and viscosity and cure kinetics of the resin. The computer model can be used to analyze the resin flow details, track the thickness change of the preform, predict the total infiltration time and final fiber volume fraction of the parts, and determine whether the resin could completely infiltrate and uniformly wet out the preform.

  12. Fast hybrid fitting energy-based active contour model for target detection

    Institute of Scientific and Technical Information of China (English)

    Dengwei Wang; Tianxu Zhang; Luxin Yan

    2011-01-01

    A novel hybrid fitting energy-based active contour model in the level set framework is proposed.The method fuses the region and boundary information of the target to achieve accurate and robust detection performance.A special extra term that penalizes the deviation of the level set function from a signed distance function is also included in our method. This term allows the time-consuming redistancing operation to be removed completely.Moreover,a fast unconditionally stable numerical scheme is introduced to solve the problem.Experimental results on real infrared images show that our method can improve target detection performance efficiently in terms of the number of iterations and the wasted central processing unit(CPU) time.

  13. POLYNOMIAL MODEL BASED FAST FRACTIONAL PIXEL SEARCH ALGORITHM FOR H.264/AVC

    Institute of Scientific and Technical Information of China (English)

    Xi Yinglai; Hao Chongyang; Lai Changcai

    2006-01-01

    This paper proposed a novel fast fractional pixel search algorithm based on polynomial model.With the analysis of distribution characteristics of motion compensation error surface inside fractional pixel searching window, the matching error is fitted with parabola along horizontal and vertical direction respectively. The proposed searching strategy needs to check only 6 points rather than 16 or 24 points, which are used in the Hierarchical Fractional Pel Search algorithm (HFPS) for 1/4-pel and 1/8-pel Motion Estimation (ME). The experimental results show that the proposed algorithm shows very good capability in keeping the rate distortion performance while reduces computation load to a large extent compared with HFPS algorithm.

  14. Evaluation of Fast-Time Wake Models Using Denver 2006 Field Experiment Data

    Science.gov (United States)

    Ahmad, Nash’at N.; Pruis, Matthew J.

    2015-01-01

    The National Aeronautics and Space Administration conducted a series of wake vortex field experiments at Denver in 2003, 2005, and 2006. This paper describes the lidar wake vortex measurements and associated meteorological data collected during the 2006 deployment, and includes results of recent reprocessing of the lidar data using a new wake vortex algorithm and estimates of the atmospheric turbulence using a new algorithm to estimate eddy dissipation rate from the lidar data. The configuration and set-up of the 2006 field experiment allowed out-of-ground effect vortices to be tracked in lateral transport further than any previous campaign and thereby provides an opportunity to study long-lived wake vortices in moderate to low crosswinds. An evaluation of NASA's fast-time wake vortex transport and decay models using the dataset shows similar performance as previous studies using other field data.

  15. Fast pedestrian detection using deformable part model and pyramid layer location

    Science.gov (United States)

    Geng, Lei; Liu, Yang; Xiao, Zhitao; Li, Yuelong; Zhang, Fang

    2017-05-01

    The majority of pedestrian detection approaches use multiscale detection and the sliding window search scheme with high computing complexity. We present a fast pedestrian detection method using the deformable part model and pyramid layer location (PLL). First, the object proposal method is used rather than the traditional sliding window to obtain pedestrian proposal regions. Then, a PLL method is proposed to select the optimal root level in the feature pyramid for each candidate window. On this basis, a single-point calculation scheme is designed to calculate the scores of candidate windows efficiently. Finally, pedestrians can be located from the images. The Institut national de recherche en informatique et en automatique dataset for human detection is used to evaluate the performance of the proposed method. The experimental results demonstrate that the proposed method can reduce the number of feature maps and windows requiring calculation in the detection process. Consequently, the computing cost is significantly reduced, with fewer false positives.

  16. A new method for the fast simulation of models of highly dependable Markov system

    Institute of Scientific and Technical Information of China (English)

    XIAO Gang; LI Zhizhong

    2005-01-01

    To fast evaluate the small probability that starts from the all-components-up state, the system hits the failed sets before returning to the all-components-up state, Important Sampling or Important Splitting is used commonly. In this paper, a new approach distinguished from Important Sampling and Important Splitting is presented to estimate this small probability of highly dependable Markov system. This new approach achieves variance reduction through improving the estimator itself. The new estimator is derived from the integral equation describing the state transitions of Markov system. That the variance of this estimator is less than that of naive simulation at all time is proved theoretically. Two example involved reliability models with deferred repair are used to compare the methods of RB, IGBS, SB-RBS, naive simulation, and the method presented in this paper. Results show our method has the least RE.

  17. Model-Based Iterative Reconstruction for Radial Fast Spin-Echo MRI

    CERN Document Server

    Block, Kai Tobias; Frahm, Jens

    2016-01-01

    In radial fast spin-echo MRI, a set of overlapping spokes with an inconsistent T2 weighting is acquired, which results in an averaged image contrast when employing conventional image reconstruction techniques. This work demonstrates that the problem may be overcome with the use of a dedicated reconstruction method that further allows for T2 quantification by extracting the embedded relaxation information. Thus, the proposed reconstruction method directly yields a spin-density and relaxivity map from only a single radial data set. The method is based on an inverse formulation of the problem and involves a modeling of the received MRI signal. Because the solution is found by numerical optimization, the approach exploits all data acquired. Further, it handles multi-coil data and optionally allows for the incorporation of additional prior knowledge. Simulations and experimental results for a phantom and human brain in vivo demonstrate that the method yields spin-density and relaxivity maps that are neither affect...

  18. Formulation Development and Evaluation of Fast Disintegrating Tablet of Cetirizine Hydrochloride: A Novel Drug Delivery for Pediatrics and Geriatrics

    Science.gov (United States)

    Sharma, Deepak; Singh, Mankaran; Kumar, Dinesh; Singh, Gurmeet

    2014-01-01

    Recent developments in fast disintegrating tablets have brought convenience in dosing to pediatric and elderly patients who have trouble in swallowing tablets. The objective of the present study was to prepare the fast disintegrating tablet of Cetirizine Hydrochloride for allergic and respiratory disorders. As precision of dosing and patient's compliance become important prerequisite for a long-term treatment, there is a need to develop a formulation for this drug which overcomes problems such as difficulty in swallowing, inconvenience in administration while travelling, and patient's acceptability. Hence, the present investigation was undertaken with a view to develop a fast disintegrating tablet of Cetirizine Hydrochloride which offers a new range of products having desired characteristics and intended benefits. Superdisintegrants such as Sodium Starch Glycolate were optimized. Different binders were optimized along with optimized superdisintegrant concentration. The tablets were prepared by direct compression technique. The tablets were evaluated for hardness, friability, weight variation, wetting time, disintegration time and uniformity of content. Optimized formulation was evaluated by in vitro dissolution test, drug excipient compatibility and accelerated stability study. It was concluded that fast disintegrating tablets of Cetirizine Hydrochloride were formulated successfully with desired characteristics which disintegrated rapidly, provide rapid onset of action, and enhance the patient convenience and compliance. PMID:26556203

  19. Formulation Development and Evaluation of Fast Disintegrating Tablet of Cetirizine Hydrochloride: A Novel Drug Delivery for Pediatrics and Geriatrics

    Directory of Open Access Journals (Sweden)

    Deepak Sharma

    2014-01-01

    Full Text Available Recent developments in fast disintegrating tablets have brought convenience in dosing to pediatric and elderly patients who have trouble in swallowing tablets. The objective of the present study was to prepare the fast disintegrating tablet of Cetirizine Hydrochloride for allergic and respiratory disorders. As precision of dosing and patient's compliance become important prerequisite for a long-term treatment, there is a need to develop a formulation for this drug which overcomes problems such as difficulty in swallowing, inconvenience in administration while travelling, and patient’s acceptability. Hence, the present investigation was undertaken with a view to develop a fast disintegrating tablet of Cetirizine Hydrochloride which offers a new range of products having desired characteristics and intended benefits. Superdisintegrants such as Sodium Starch Glycolate were optimized. Different binders were optimized along with optimized superdisintegrant concentration. The tablets were prepared by direct compression technique. The tablets were evaluated for hardness, friability, weight variation, wetting time, disintegration time and uniformity of content. Optimized formulation was evaluated by in vitro dissolution test, drug excipient compatibility and accelerated stability study. It was concluded that fast disintegrating tablets of Cetirizine Hydrochloride were formulated successfully with desired characteristics which disintegrated rapidly, provide rapid onset of action, and enhance the patient convenience and compliance.

  20. Continuous Evaluation of Fast Processes in Climate Models Using ARM Measurements

    Energy Technology Data Exchange (ETDEWEB)

    Li, Zhijin [Univ. of California, Los Angeles, CA (United States); Sha, Feng [Univ. of California, Los Angeles, CA (United States); Liu, Yangang [Brookhaven National Lab. (BNL), Upton, NY (United States); Lin, Wuyin [Brookhaven National Lab. (BNL), Upton, NY (United States); Toto, Tami [Brookhaven National Lab. (BNL), Upton, NY (United States); Vogelmann, Andrew [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2016-02-02

    This five-year award supports the project “Continuous Evaluation of Fast Processes in Climate Models Using ARM Measurements (FASTER)”. The goal of this project is to produce accurate, consistent and comprehensive data sets for initializing both single column models (SCMs) and cloud resolving models (CRMs) using data assimilation. A multi-scale three-dimensional variational data assimilation scheme (MS-3DVAR) has been implemented. This MS-3DVAR system is built on top of WRF/GSI. The Community Gridpoint Statistical Interpolation (GSI) system is an operational data assimilation system at the National Centers for Environmental Prediction (NCEP) and has been implemented in the Weather Research and Forecast (WRF) model. This MS-3DVAR is further enhanced by the incorporation of a land surface 3DVAR scheme and a comprehensive aerosol 3DVAR scheme. The data assimilation implementation focuses in the ARM SGP region. ARM measurements are assimilated along with other available satellite and radar data. Reanalyses are then generated for a few selected period of time. This comprehensive data assimilation system has also been employed for other ARM-related applications.

  1. Pumps modelling of a sodium fast reactor design and analysis of hydrodynamic behavior

    Directory of Open Access Journals (Sweden)

    Ordóñez Ródenas José

    2016-01-01

    Full Text Available One of the goals of Generation IV reactors is to increase safety from those of previous generations. Different research platforms have been identified the need to improve the reliability of the simulation tools to ensure the capability of the plant to accommodate the design basis transients established in preliminary safety studies. The paper describes the modelling of primary pumps in advanced sodium cooled reactors using the TRACE code. Following the implementation of the models, the results obtained in the analysis of different design basis transients are compared with the simplifying approximations used in reference models. The paper shows the process to obtain a consistent pump model of the ESFR (European Sodium Fast Reactor design and the analysis of loss of flow transients triggered by pumps coast–down analyzing the thermal hydraulic neutronic coupled system response. A sensitivity analysis of the system pressure drops effect and the other relevant parameters that influence the natural convection after the pumps coast–down is also included.

  2. General relativistic considerations of the field shedding model of fast radio bursts

    Science.gov (United States)

    Punsly, Brian; Bini, Donato

    2016-06-01

    Popular models of fast radio bursts (FRBs) involve the gravitational collapse of neutron star progenitors to black holes. It has been proposed that the shedding of the strong neutron star magnetic field (B) during the collapse is the power source for the radio emission. Previously, these models have utilized the simplicity of the Schwarzschild metric which has the restriction that the magnetic flux is magnetic `hair' that must be shed before final collapse. But neutron stars have angular momentum and charge and a fully relativistic Kerr-Newman solution exists in which B has its source inside of the event horizon. In this Letter, we consider the magnetic flux to be shed as a consequence of the electric discharge of a metastable collapsed state of a Kerr-Newman black hole. It has also been argued that the shedding model will not operate due to pair creation. By considering the pulsar death line, we find that for a neutron star with B = 1011-1013 G and a long rotation period, >1s this is not a concern. We also discuss the observational evidence supporting the plausibility of magnetic flux shedding models of FRBs that are spawned from rapidly rotating progenitors.

  3. Determinants of developing diabetes mellitus and vascular complications in patients with impaired fasting glucose

    Directory of Open Access Journals (Sweden)

    Faranak Sharifi

    2013-01-01

    Full Text Available Aims: To detect the risk factors of diabetes mellitus (DM and cardiovascular complications in subjects with impaired fasting glucose (IFG. Materials and Methods: One hundred and twenty three subjects with proved IFG in Zanjan Healthy Heart Study (2002-2003 were recalled and participated in this study (2009-2010. Demographic and laboratoryinformation of the participants were collected.Ischemic heart disease (IHD was assessed by the exercise tolerance test (ETT. All the subjects with abnormal ETT or documented past history of IHD confirmed by angiographic evaluation. Ophthalmic complications including cataract, glaucoma, and diabetic retinopathy were estimated by an ophthalmologist. Results: Incidence of DM was 19.5%. All the diabetic and pre-diabetic patients had at least one of the other components of metabolic syndrome. Obesity (P: 0.04, OR: 1.8, 95%CI: 1.2-9 and low physical activity (P < 0.001, OR: 9.6, 95%CI: 3.4-32 were the only independent prognostic risk factors for progression to DM in patients with IFG. Total incidence of IHD was 14.6% and had a strong correlation with sex (P: 0.01, OR: 1.8, 95%CI: 1.2-1.5, age (P < 0.001, OR: 23, 95%CI: 2.1-67 and cigarette smoking (P < 0.001, OR: 36.5, 95%CI: 3.9-337. Non-proliferative diabetic retinopathy was shown in 2 (1.6% subjects who were all women. Conclusion: Obesity and low physical activity are the main factors of developing DM and its macrovascular complications in subjects with IFG.

  4. Regulatory Technology Development Plan - Sodium Fast Reactor. Mechanistic Source Term - Metal Fuel Radionuclide Release

    Energy Technology Data Exchange (ETDEWEB)

    Grabaskas, David [Argonne National Lab. (ANL), Argonne, IL (United States); Bucknor, Matthew [Argonne National Lab. (ANL), Argonne, IL (United States); Jerden, James [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-02-01

    The development of an accurate and defensible mechanistic source term will be vital for the future licensing efforts of metal fuel, pool-type sodium fast reactors. To assist in the creation of a comprehensive mechanistic source term, the current effort sought to estimate the release fraction of radionuclides from metal fuel pins to the primary sodium coolant during fuel pin failures at a variety of temperature conditions. These release estimates were based on the findings of an extensive literature search, which reviewed past experimentation and reactor fuel damage accidents. Data sources for each radionuclide of interest were reviewed to establish release fractions, along with possible release dependencies, and the corresponding uncertainty levels. Although the current knowledge base is substantial, and radionuclide release fractions were established for the elements deemed important for the determination of offsite consequences following a reactor accident, gaps were found pertaining to several radionuclides. First, there is uncertainty regarding the transport behavior of several radionuclides (iodine, barium, strontium, tellurium, and europium) during metal fuel irradiation to high burnup levels. The migration of these radionuclides within the fuel matrix and bond sodium region can greatly affect their release during pin failure incidents. Post-irradiation examination of existing high burnup metal fuel can likely resolve this knowledge gap. Second, data regarding the radionuclide release from molten high burnup metal fuel in sodium is sparse, which makes the assessment of radionuclide release from fuel melting accidents at high fuel burnup levels difficult. This gap could be addressed through fuel melting experimentation with samples from the existing high burnup metal fuel inventory.

  5. Motorola Secure Software Development Model

    Directory of Open Access Journals (Sweden)

    Francis Mahendran

    2008-08-01

    Full Text Available In today's world, the key to meeting the demand for improved security is to implement repeatable processes that reliably deliver measurably improved security. While many organizations have announced efforts to institutionalize a secure software development process, there is little or no industry acceptance for a common process improvement framework for secure software development. Motorola has taken the initiative to develop such a framework, and plans to share this with the Software Engineering Institute for possible inclusion into its Capability Maturity Model Integration (CMMI®. This paper will go into the details of how Motorola is addressing this issue. The model that is being developed is designed as an extension of the existing CMMI structure. The assumption is that the audience will have a basic understanding of the SEI CMM® / CMMI® process framework. The paper will not describe implementation details of a security process model or improvement framework, but will address WHAT security practices are required for a company with many organizations operating at different maturity levels. It is left to the implementing organization to answer the HOW, WHEN, WHO and WHERE aspects. The paper will discuss how the model is being implemented in the Motorola Software Group.

  6. Development of a fast multi-line x-ray CT detector for NDT

    Science.gov (United States)

    Hofmann, T.; Nachtrab, F.; Schlechter, T.; Neubauer, H.; Mühlbauer, J.; Schröpfer, S.; Ernst, J.; Firsching, M.; Schweiger, T.; Oberst, M.; Meyer, A.; Uhlmann, N.

    2015-04-01

    Typical X-ray detectors for non-destructive testing (NDT) are line detectors or area detectors, like e.g. flat panel detectors. Multi-line detectors are currently only available in medical Computed Tomography (CT) scanners. Compared to flat panel detectors, line and multi-line detectors can achieve much higher frame rates. This allows time-resolved 3D CT scans of an object under investigation. Also, an improved image quality can be achieved due to reduced scattered radiation from object and detector themselves. Another benefit of line and multi-line detectors is that very wide detectors can be assembled easily, while flat panel detectors are usually limited to an imaging field with a size of approx. 40 × 40 cm2 at maximum. The big disadvantage of line detectors is the limited number of object slices that can be scanned simultaneously. This leads to long scan times for large objects. Volume scans with a multi-line detector are much faster, but with almost similar image quality. Due to the promising properties of multi-line detectors their application outside of medical CT would also be very interesting for NDT. However, medical CT multi-line detectors are optimized for the scanning of human bodies. Many non-medical applications require higher spatial resolutions and/or higher X-ray energies. For those non-medical applications we are developing a fast multi-line X-ray detector.In the scope of this work, we present the current state of the development of the novel detector, which includes several outstanding properties like an adjustable curved design for variable focus-detector-distances, conserving nearly uniform perpendicular irradiation over the entire detector width. Basis of the detector is a specifically designed, radiation hard CMOS imaging sensor with a pixel pitch of 200 μ m. Each pixel has an automatic in-pixel gain adjustment, which allows for both: a very high sensitivity and a wide dynamic range. The final detector is planned to have 256 lines of

  7. Development of the fast arcing protection for ECRH system on the HL-2A tokamak

    Institute of Scientific and Technical Information of China (English)

    LI Xiu-juan; RAO Jun; WANG Ming-wei; WANG Xue-yun; LI Bo

    2007-01-01

    The fast arcing protection of the electron cyclotron resonance heating(ECRH)is very important in the heating experiment of the HL-2A tokamak.ECRH has the ability of 1MW using two gyrotrons (each about 500kW).The states of the protected objects must been detect then deal with effectively arcing-events in order to accomplish the protection function.The fast arcing protection includes two parts such as some arcing detectors and one arcing protector for the one gyrotron and one waveguide line.The ECRH arcing protection system must be fast enough and very reliable,and the total response time is less than 25μs.

  8. Modeling Fast-scan Cyclic Voltammetry Data from Electrically Stimulated Dopamine Neurotransmission Data Using QNsim1.0.

    Science.gov (United States)

    Harun, Rashed; Grassi, Christine M; Munoz, Miranda J; Wagner, Amy K

    2017-06-05

    Central dopaminergic (DAergic) pathways have an important role in a wide range of functions, such as attention, motivation, and movement. Dopamine (DA) is implicated in diseases and disorders including attention deficit hyperactivity disorder, Parkinson's disease, and traumatic brain injury. Thus, DA neurotransmission and the methods to study it are of intense scientific interest. In vivo fast-scan cyclic voltammetry (FSCV) is a method that allows for selectively monitoring DA concentration changes with fine temporal and spatial resolution. This technique is commonly used in conjunction with electrical stimulations of ascending DAergic pathways to control the impulse flow of dopamine neurotransmission. Although the stimulated DA neurotransmission paradigm can produce robust DA responses with clear morphologies, making them amenable for kinetic analysis, there is still much debate on how to interpret the responses in terms of their DA release and clearance components. To address this concern, a quantitative neurobiological (QN) framework of stimulated DA neurotransmission was recently developed to realistically model the dynamics of DA release and reuptake over the course of a stimulated DA response. The foundations of this model are based on experimental data from stimulated DA neurotransmission and on principles of neurotransmission adopted from various lines of research. The QN model implements 12 parameters related to stimulated DA release and reuptake dynamics to model DA responses. This work describes how to simulate DA responses using QNsim1.0 and also details principles that have been implemented to systematically discern alterations in the stimulated dopamine release and reuptake dynamics.

  9. Research and development in welding and hardfacing towards construction of prototype fast breeder reactor

    Energy Technology Data Exchange (ETDEWEB)

    Albert, S.K.; Bhaduri, A.K. [Indira Gandhi Centre for Atomic Research, Kalpakkam (India)

    2012-07-01

    India's 500MWe Prototype Fast Breeder Reactor (PFBR) is in advanced stage of construction at Kalpakkam and this reactor is expected to be commissioned in the year 2013. Extensive research and development activities in various fields like material development, welding, forming, non-destructive testing etc. were undertaken before the actual construction of the reactor began. Many of these activities are still continuing with the objectives of conducting functional tests, generating data, validating the design and meeting the various regulatory requirements. In welding, initial challenge was to develop indigenous welding consumables with a specification more stringent than that is given in most of the national and international standards. The welding consumable specified for 316LN austenitic stainless steel is E316-15M with strict control on delta ferrite content, toughness requirement after 750 C/100 h ageing to ensure adequate resistance to embrittlement during prolonged high temperature exposure and good slag detachability. This consumable was successfully developed in collaboration with Indian consumable manufacturers and is being used for fabrication of almost all PFBR components and piping made of 316LN stainless steel. Similarly, electrodes of welding of modified 9Cr-1Mo steel (material of construction for PFBR steam generator) with requirement of RTNDT requirement of ≤ -5 C was also developed indigenously. Extensive studies were also carried out on weldability of various austenitic stainless steels and modified 9Cr-1Mo steel used in PFBR. Hot cracking susceptibility of alloy D9 (15Cr-15Ni-2Mo-Ti alloy), the material chosen for fuel clab tube and fuel sub-assembly, and 316LN stainless steel was extensively studied using varestraint testing and Gleeble simulation. Results from these steels were used in developing welding procedures for various reactor components. Hydrogen assisted cracking susceptibility (HAC) of modified 9Cr-1Mo steel was studied using

  10. Modelling hormonal response and development.

    Science.gov (United States)

    Voß, Ute; Bishopp, Anthony; Farcot, Etienne; Bennett, Malcolm J

    2014-05-01

    As our knowledge of the complexity of hormone homeostasis, transport, perception, and response increases, and their outputs become less intuitive, modelling is set to become more important. Initial modelling efforts have focused on hormone transport and response pathways. However, we now need to move beyond the network scales and use multicellular and multiscale modelling approaches to predict emergent properties at different scales. Here we review some examples where such approaches have been successful, for example, auxin-cytokinin crosstalk regulating root vascular development or a study of lateral root emergence where an iterative cycle of modelling and experiments lead to the identification of an overlooked role for PIN3. Finally, we discuss some of the remaining biological and technical challenges. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  11. Development towards a fast ion loss detector for the reversed field pinch

    Science.gov (United States)

    Bonofiglo, P. J.; Anderson, J. K.; Almagri, A. F.; Kim, J.; Clark, J.; Capecchi, W.; Sears, S. H.; Egedal, J.

    2016-11-01

    A fast ion loss detector has been constructed and implemented on the Madison Symmetric Torus (MST) to investigate energetic ion losses and transport due to energetic particle and MHD instabilities. The detector discriminates particle orbits solely on pitch and consists of two thin-foil, particle collecting plates that are symmetric with respect to the device aperture. One plate collects fast ion signal, while the second aids in the minimization of background and noise effects. Initial measurements are reported along with suggestions for the next design phase of the detector.

  12. Development of a fast GC/MS-system for airborne measurements of Volatile Organic Compounds

    Science.gov (United States)

    Wenk, Ann-Kathrin; Wegener, Robert; Hofzumahaus, Andreas; Wahner, Andreas

    2010-05-01

    Volatile Organic Compounds (VOC) determine the radical chemistry of the atmosphere. They can serve both as sources, or sinks for radicals. Mass spectrometry linked to gas chromatography (GC/MS) is a widespread technique in environmental analysis since it can be used to separate and analyze any compound which can be evaporated and pass the analytical column with very high precision and a good sensitivity. The use of special chromatographic phases and long capillary columns enables the quantification of a wide range of compounds with little interference from other sample constituents. An in situ GC/MS consists in principle of three compartments, 1) a preconcentration unit where the sample is extracted from the air, focussed onto a small volume and volatilized, 2) a chromatographic system where the analytes are separated on the analytical column and 3) a mass spectrometer where the compounds are ionized and detected. VOC have to be preconcentrated due to their low concentration level and in order to get enough sensitivity for analysis. The aim of this project was to develop an in situ GC/MS system to analyze volatile Nonmethane Hydrocarbons (NMHC) and Oxygenated Volatile Organic Compounds (OVOC) for the High Altitude and LOng Range Research Aircraft (HALO). In contrast to other analytical instruments a GC/MS works discontinuously. The preconcentration unit is either heated up when the compounds are volatilized or cooled down when substances are adsorbed. The same is true for the GC oven. It is heated up when the compounds are separated or it is cooled down to be ready for the next injection. On a system with a single GC oven, these processes will inevitably lengthen the whole analytical procedure. To speed up the analytical process the GC/MS system described here was equipped with two GC ovens and two adsorption units. While the components are adsorbed in one adsorption unit, in the other unit the components are desorbed and transferred to the GC unit. The second GC

  13. Hybrid Finite Element-Fast Spectral Domain Multilayer Boundary Integral Modeling of Doubly Periodic Structures

    Energy Technology Data Exchange (ETDEWEB)

    T.F. Eibert; J.L. Volakis; Y.E. Erdemli

    2002-03-03

    Hybrid finite element (FE)--boundary integral (BI) analysis of infinite periodic arrays is extended to include planar multilayered Green's functions. In this manner, a portion of the volumetric dielectric region can be modeled via the finite element method whereas uniform multilayered regions can be modeled using a multilayered Green's function. As such, thick uniform substrates can be modeled without loss of efficiency and accuracy. The multilayered Green's function is analytically computed in the spectral domain and the resulting BI matrix-vector products are evaluated via the fast spectral domain algorithm (FSDA). As a result, the computational cost of the matrix-vector products is kept at O(N). Furthermore, the number of Floquet modes in the expansion are kept very few by placing the BI surfaces within the computational unit cell. Examples of frequency selective surface (FSS) arrays are analyzed with this method to demonstrate the accuracy and capability of the approach. One example involves complicated multilayered substrates above and below an inhomogeneous filter element and the other is an optical ring-slot array on a substrate several hundred wavelengths in thickness. Comparisons with measurements are included.

  14. General Relativistic Considerations of the Field Shedding Model of Fast Radio Bursts

    CERN Document Server

    Punsly, Brian

    2016-01-01

    Popular models of fast radio bursts (FRBs) involve the gravitational collapse of neutron star progenitors to black holes. It has been proposed that the shedding of the strong neutron star magnetic field ($B$) during the collapse is the power source for the radio emission. Previously, these models have utilized the simplicity of the Schwarzschild metric which has the restriction that the magnetic flux is magnetic "hair" that must be shed before final collapse. But, neutron stars have angular momentum and charge and a fully relativistic Kerr Newman solution exists in which $B$ has its source inside of the event horizon. In this letter, we consider the magnetic flux to be shed as a consequence of the electric discharge of a metastable collapsed state of a Kerr Newman black hole. It has also been argued that the shedding model will not operate due to pair creation. By considering the pulsar death line, we find that for a neutron star with $B = 10^{11} - 10^{13}$ G and a long rotation period, $>1$ s this is not a ...

  15. Development of Observation Techniques in Reactor Vessel of Experimental Fast Reactor Joyo

    Science.gov (United States)

    Takamatsu, Misao; Imaizumi, Kazuyuki; Nagai, Akinori; Sekine, Takashi; Maeda, Yukimoto

    In-Vessel Observations (IVO) techniques for Sodium cooled Fast Reactors (SFRs) are important in confirming its safety and integrity. And several IVO equipments for an SFR are developed. However, in order to secure the reliability of IVO techniques, it was necessary to demonstrate the performance under the actual reactor environment with high temperature, high radiation dose and remained sodium. During the investigation of an incident that occurred with Joyo, IVO using a standard Video Camera (VC) and a Radiation-Resistant Fiberscope (RRF) took place at (1) the top of the Sub-Assemblies (S/As) and the In-Vessel Storage rack (IVS), (2) the bottom face of the Upper Core Structure (UCS). A simple 6 m overhead view of each S/A, through the fuel handling or inspection holes etc, was photographed using a VC for making observations of the top of S/As and IVS. About 650 photographs were required to create a composite photograph of the top of the entire S/As and IVS, and a resolution was estimated to be approximately 1mm. In order to observe the bottom face of the UCS, a Remote Handling Device (RHD) equipped with RRFs (approximately 13 m long) was specifically developed for Joyo with a tip that could be inserted into the 70 mm gap between the top of the S/As and the bottom of the UCS. A total of about 35,000 photographs were needed for the full investigation. Regarding the resolution, the sodium flow regulating grid of 0.8mm in thickness could be discriminated. The performance of IVO equipments under the actual reactor environment was successfully confirmed. And the results provided useful information on incident investigations. In addition, fundamental findings and the experience gained during this study, which included the design of equipment, operating procedures, resolution, lighting adjustments, photograph composition and the durability of the RRF under radiation exposure, provided valuable insights into further improvements and verifications for IVO techniques to

  16. The HIRLAM fast radiation scheme for mesoscale numerical weather prediction models

    Directory of Open Access Journals (Sweden)

    L. Rontu

    2017-07-01

    Full Text Available This paper provides an overview of the HLRADIA shortwave (SW and longwave (LW broadband radiation schemes used in the HIRLAM numerical weather prediction (NWP model and available in the HARMONIE-AROME mesoscale NWP model. The advantage of broadband, over spectral, schemes is that they can be called more frequently within the model, without compromising on computational efficiency. In mesoscale models fast interactions between clouds and radiation and the surface and radiation can be of greater importance than accounting for the spectral details of clear-sky radiation; thus calling the routines more frequently can be of greater benefit than the deterioration due to loss of spectral details. Fast but physically based radiation parametrizations are expected to be valuable for high-resolution ensemble forecasting, because as well as the speed of their execution, they may provide realistic physical perturbations. Results from single-column diagnostic experiments based on CIRC benchmark cases and an evaluation of 10 years of radiation output from the FMI operational archive of HIRLAM forecasts indicate that HLRADIA performs sufficiently well with respect to the clear-sky downwelling SW and longwave LW fluxes at the surface. In general, HLRADIA tends to overestimate surface fluxes, with the exception of LW fluxes under cold and dry conditions. The most obvious overestimation of the surface SW flux was seen in the cloudy cases in the 10-year comparison; this bias may be related to using a cloud inhomogeneity correction, which was too large. According to the CIRC comparisons, the outgoing LW and SW fluxes at the top of atmosphere are mostly overestimated by HLRADIA and the net LW flux is underestimated above clouds. The absorption of SW radiation by the atmosphere seems to be underestimated and LW absorption seems to be overestimated. Despite these issues, the overall results are satisfying and work on the improvement of HLRADIA for the use in HARMONIE

  17. The HIRLAM fast radiation scheme for mesoscale numerical weather prediction models

    Science.gov (United States)

    Rontu, Laura; Gleeson, Emily; Räisänen, Petri; Pagh Nielsen, Kristian; Savijärvi, Hannu; Hansen Sass, Bent

    2017-07-01

    This paper provides an overview of the HLRADIA shortwave (SW) and longwave (LW) broadband radiation schemes used in the HIRLAM numerical weather prediction (NWP) model and available in the HARMONIE-AROME mesoscale NWP model. The advantage of broadband, over spectral, schemes is that they can be called more frequently within the model, without compromising on computational efficiency. In mesoscale models fast interactions between clouds and radiation and the surface and radiation can be of greater importance than accounting for the spectral details of clear-sky radiation; thus calling the routines more frequently can be of greater benefit than the deterioration due to loss of spectral details. Fast but physically based radiation parametrizations are expected to be valuable for high-resolution ensemble forecasting, because as well as the speed of their execution, they may provide realistic physical perturbations. Results from single-column diagnostic experiments based on CIRC benchmark cases and an evaluation of 10 years of radiation output from the FMI operational archive of HIRLAM forecasts indicate that HLRADIA performs sufficiently well with respect to the clear-sky downwelling SW and longwave LW fluxes at the surface. In general, HLRADIA tends to overestimate surface fluxes, with the exception of LW fluxes under cold and dry conditions. The most obvious overestimation of the surface SW flux was seen in the cloudy cases in the 10-year comparison; this bias may be related to using a cloud inhomogeneity correction, which was too large. According to the CIRC comparisons, the outgoing LW and SW fluxes at the top of atmosphere are mostly overestimated by HLRADIA and the net LW flux is underestimated above clouds. The absorption of SW radiation by the atmosphere seems to be underestimated and LW absorption seems to be overestimated. Despite these issues, the overall results are satisfying and work on the improvement of HLRADIA for the use in HARMONIE-AROME NWP system

  18. Experimental research subject and renovation of chemical processing facility (CPF) for advanced fast reactor fuel reprocessing technology development

    Energy Technology Data Exchange (ETDEWEB)

    Koyama, Tomozo; Shinozaki, Tadahiro; Nomura, Kazunori; Koma, Yoshikazu; Miyachi, Shigehiko; Ichige, Yoshiaki; Kobayashi, Tsuguyuki; Nemoto, Shin-ichi [Japan Nuclear Cycle Development Inst., Tokai Works, Tokai, Ibaraki (Japan)

    2002-12-01

    In order to enhance economical efficiency, environmental impact and nuclear nonproliferation resistance, the Advanced Reprocessing Technology, such as simplification and optimization of process, and applicability evaluation of the innovative technology that was not adopted up to now, has been developed for the reprocessing of the irradiated fuel taken out from a fast reactor. Renovation of the hot cell interior equipments, establishment and updating of glove boxes, installation of various analytical equipments, etc. in the Chemical Processing Facility (CPF) was done to utilize the CPF more positivity which is the center of the experimental field, where actual fuel can be used, for research and development towards establishment of the Advanced Reprocessing Technology development. The hot trials using the irradiated fuel pins of the experimental fast reactor 'JOYO' for studies on improved aqueous reprocessing technology, MA separation technology, dry process technology, etc. are scheduled to be carried out with these new equipments. (author)

  19. Analysis of Fast-Scale Bifurcation in Peak Current Controlled Buck-Boost Inverter Based on Unified Averaged Model

    Science.gov (United States)

    Zhang, Hao; Dong, Shuai; Guan, Weimin; Liu, Ye

    In this paper, a unified averaged modeling method is proposed to investigate the fast-scale period-doubling bifurcation of a full-bridge integrated buck-boost inverter with peak current control. In order to increase the resolution of the conventional classic averaged model to half the switching frequency, sample-and-hold effect of inductor current is absorbed into the averaged model, i.e. the proposed unified averaged model can capture the high-frequency dynamical characteristics of the buck-boost inverter, which is both an extension and a modification of conventional averaged model. Based on the unified mode, fast-scale bifurcation is identified, and the corresponding bifurcation point is predicted with the help of the locus movement of all the poles, and their underlying mechanisms are revealed. Detailed analysis shows that the occurrence of high-frequency oscillation means fast-scale bifurcation, while the occurrence of low-frequency oscillation leads to slow-scale bifurcation. Finally, it is demonstrated that the unified averaged model can provide not only a general method to investigate both the slow- and fast-scale bifurcations in a unified framework but also a quite straightforward design-oriented method which can be directly applicable.

  20. Fabrication Technological Development of the Oxide Dispersion Strengthened Alloy MA957 for Fast Reactor Applications

    Energy Technology Data Exchange (ETDEWEB)

    Hamilton, Margaret L.; Gelles, David S.; Lobsinger, Ralph J.; Johnson, Gerald D.; Brown, W. F.; Paxton, Michael M.; Puigh, Raymond J.; Eiholzer, Cheryl R.; Martinez, C.; Blotter, M. A.

    2000-02-28

    A significant amount of effort has been devoted to determining the properties and understanding the behavior of the alloy MA957 to define its potential usefulness as a cladding material in the fast breeder reactor program. The numerous characterization and fabrication studies that were conducted are documented in this report.

  1. The Effects of the Fast Track Preventive Intervention on the Development of Conduct Disorder across Childhood

    Science.gov (United States)

    Child Development, 2011

    2011-01-01

    The impact of the Fast Track intervention on externalizing disorders across childhood was examined. Eight hundred-ninety-one early-starting children (69% male; 51% African American) were randomly assigned by matched sets of schools to intervention or control conditions. The 10-year intervention addressed parent behavior-management, child social…

  2. Curriculum Development in the Language Arts. Focused Access to Selected Topics (FAST) Bib No. 65.

    Science.gov (United States)

    Warren, John

    This ERIC "FAST Bib" provides annotations of ERIC documents and journal articles that address the question of how to balance two opposing forces operating in today's schools, i.e., the forces of change and complacency, to establish an exemplary language arts curriculum that is a reality and not just a theoretical mirage. The 18…

  3. Regulatory Technology Development Plan - Sodium Fast Reactor. Mechanistic Source Term - Trial Calculation. Work Plan

    Energy Technology Data Exchange (ETDEWEB)

    Grabaskas, David [Argonne National Lab. (ANL), Argonne, IL (United States); Bucknor, Matthew [Argonne National Lab. (ANL), Argonne, IL (United States); Jerden, James [Argonne National Lab. (ANL), Argonne, IL (United States); Brunett, Acacia J. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-02-01

    The overall objective of the SFR Regulatory Technology Development Plan (RTDP) effort is to identify and address potential impediments to the SFR regulatory licensing process. In FY14, an analysis by Argonne identified the development of an SFR-specific MST methodology as an existing licensing gap with high regulatory importance and a potentially long lead-time to closure. This work was followed by an initial examination of the current state-of-knowledge regarding SFR source term development (ANLART-3), which reported several potential gaps. Among these were the potential inadequacies of current computational tools to properly model and assess the transport and retention of radionuclides during a metal fuel pool-type SFR core damage incident. The objective of the current work is to determine the adequacy of existing computational tools, and the associated knowledge database, for the calculation of an SFR MST. To accomplish this task, a trial MST calculation will be performed using available computational tools to establish their limitations with regard to relevant radionuclide release/retention/transport phenomena. The application of existing modeling tools will provide a definitive test to assess their suitability for an SFR MST calculation, while also identifying potential gaps in the current knowledge base and providing insight into open issues regarding regulatory criteria/requirements. The findings of this analysis will assist in determining future research and development needs.

  4. Space market model development project

    Science.gov (United States)

    Bishop, Peter C.

    1987-01-01

    The objectives of the research program, Space Market Model Development Project, (Phase 1) were: (1) to study the need for business information in the commercial development of space; and (2) to propose a design for an information system to meet the identified needs. Three simultaneous research strategies were used in proceeding toward this goal: (1) to describe the space business information which currently exists; (2) to survey government and business representatives on the information they would like to have; and (3) to investigate the feasibility of generating new economical information about the space industry.

  5. Supo Thermal Model Development II

    Energy Technology Data Exchange (ETDEWEB)

    Wass, Alexander Joseph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-07-14

    This report describes the continuation of the Computational Fluid Dynamics (CFD) model of the Supo cooling system described in the report, Supo Thermal Model Development1, by Cynthia Buechler. The goal for this report is to estimate the natural convection heat transfer coefficient (HTC) of the system using the CFD results and to compare those results to remaining past operational data. Also, the correlation for determining radiolytic gas bubble size is reevaluated using the larger simulation sample size. The background, solution vessel geometry, mesh, material properties, and boundary conditions are developed in the same manner as the previous report. Although, the material properties and boundary conditions are determined using the appropriate experiment results for each individual power level.

  6. Setting development goals using stochastic dynamical system models

    Science.gov (United States)

    Nicolis, Stamatios C.; Bali Swain, Ranjula; Sumpter, David J. T.

    2017-01-01

    The Millennium Development Goals (MDG) programme was an ambitious attempt to encourage a globalised solution to important but often-overlooked development problems. The programme led to wide-ranging development but it has also been criticised for unrealistic and arbitrary targets. In this paper, we show how country-specific development targets can be set using stochastic, dynamical system models built from historical data. In particular, we show that the MDG target of two-thirds reduction of child mortality from 1990 levels was infeasible for most countries, especially in sub-Saharan Africa. At the same time, the MDG targets were not ambitious enough for fast-developing countries such as Brazil and China. We suggest that model-based setting of country-specific targets is essential for the success of global development programmes such as the Sustainable Development Goals (SDG). This approach should provide clear, quantifiable targets for policymakers. PMID:28241057

  7. Setting development goals using stochastic dynamical system models.

    Science.gov (United States)

    Ranganathan, Shyam; Nicolis, Stamatios C; Bali Swain, Ranjula; Sumpter, David J T

    2017-01-01

    The Millennium Development Goals (MDG) programme was an ambitious attempt to encourage a globalised solution to important but often-overlooked development problems. The programme led to wide-ranging development but it has also been criticised for unrealistic and arbitrary targets. In this paper, we show how country-specific development targets can be set using stochastic, dynamical system models built from historical data. In particular, we show that the MDG target of two-thirds reduction of child mortality from 1990 levels was infeasible for most countries, especially in sub-Saharan Africa. At the same time, the MDG targets were not ambitious enough for fast-developing countries such as Brazil and China. We suggest that model-based setting of country-specific targets is essential for the success of global development programmes such as the Sustainable Development Goals (SDG). This approach should provide clear, quantifiable targets for policymakers.

  8. Modelling meristem development in plants

    OpenAIRE

    Heisler, Marcus G.; Jönsson, Henrik

    2007-01-01

    Meristems continually supply new cells for post-embryonic plant development and coordinate the initiation of new organs, such as leaves and flowers. Meristem function is regulated by a large and interconnected dynamic system that includes transcription networks, intercellular protein signalling, polarized transport of hormones and a constantly changing cellular topology. Mathematical modelling, in which the dynamics of a system are simulated using explicitly defined interactions, can serve as...

  9. Development and validation of a fast voxel-based dose evaluation system in nuclear medicine

    Science.gov (United States)

    Lu, Cheng-Chang; Lin, Hsin-Hon; Chuang, Keh-Shih; Dong, Shang-Lung; Wu, Jay; Ni, Yu-Ching; Jan, Meei-Ling

    2014-11-01

    PET imaging has been widely used in the detection and staging of malignancies and the evaluation of patient-specific dosimetry for PET scans is important in nuclear medicine. However, patient-specific dosimetry can be estimated only by Monte Carlo methods which are usually time-consuming. The purpose of this study is to develop a fast dose evaluation system namely SimDOSE. SimDOSE is a Monte Carlo code embedded in SimSET with a dose scoring routine to record the deposited energy of the photons and electrons. Fluorine-18 is one of the most commonly used radionuclides that decay predominantly by positron emission. Only a 635 keV (Emax) positron and two annihilation photons should be concerned in F-18 radiation dosimetry, hence simulation is relatively simple. To evaluate the effects of resolution, an F-18 point source placed in a 20 cm diameter sphere filled with water was simulated by SimDOSE and GATE v6.1. Grid sizes of 1 mm, 3 mm, and 5 mm were tested and each was simulated with a total of 107 decays. The resultant dose distribution functions were compared. Dose evaluation on ORNL phantom was also performed to validate the accuracy of SimDOSE. The grid size of phantom was set as 3 mm and the number of decays was 107. The S-values of liver computed by SimDOSE were compared with GATE and OLINDA (Organ Level INternal Dose Assessment) for 11C, 15O, and 18F.Finally, the CPU time of simulations was compared between SimDOSE and GATE. The dose profiles show the absorption doses located 3 mm outside the center are similar between SimDOSE and GATE. However, 71% (19%) difference of the center dose between SimDOSE and GATE are observed for 1 mm (3 mm) grid. The differences of the profile lie in the assumption in SimDOSE that all kinetic energies of electrons are locally absorbed. The ratios of S values of (SimDOSE/OLINDA) range from 0.95 to 1.11 with a mean value of 1.02±0.043. To compare simulation time from SimDOSE to GATE for calculation of 1 mm, 3 mm, 5 mm gird point

  10. Developing a Malaysia flood model

    Science.gov (United States)

    Haseldine, Lucy; Baxter, Stephen; Wheeler, Phil; Thomson, Tina

    2014-05-01

    Faced with growing exposures in Malaysia, insurers have a need for models to help them assess their exposure to flood losses. The need for an improved management of flood risks has been further highlighted by the 2011 floods in Thailand and recent events in Malaysia. The increasing demand for loss accumulation tools in Malaysia has lead to the development of the first nationwide probabilistic Malaysia flood model, which we present here. The model is multi-peril, including river flooding for thousands of kilometres of river and rainfall-driven surface water flooding in major cities, which may cause losses equivalent to river flood in some high-density urban areas. The underlying hazard maps are based on a 30m digital surface model (DSM) and 1D/2D hydraulic modelling in JFlow and RFlow. Key mitigation schemes such as the SMART tunnel and drainage capacities are also considered in the model. The probabilistic element of the model is driven by a stochastic event set based on rainfall data, hence enabling per-event and annual figures to be calculated for a specific insurance portfolio and a range of return periods. Losses are estimated via depth-damage vulnerability functions which link the insured damage to water depths for different property types in Malaysia. The model provides a unique insight into Malaysian flood risk profiles and provides insurers with return period estimates of flood damage and loss to property portfolios through loss exceedance curve outputs. It has been successfully validated against historic flood events in Malaysia and is now being successfully used by insurance companies in the Malaysian market to obtain reinsurance cover.

  11. A (fast) 'precipiton' method to calculate river hydrodynamics with applications to landscape evolution models as well as flood prediction

    Science.gov (United States)

    Davy, P.

    2013-12-01

    Particle-based methods have been popular to develop models of landscape evolution able to reproduce complex features such as dynamical braided patterns. Such a high-resolution high-frequency geomorphical structures are beyond the scope of simple landscape evolution model, whose hydrodynamics description is much too rudimentary, and hardly modeled with sophisticated CFD models because of computational time. Solving hydrodynamics remains however a major issue for the particle-based models, which may cast doubt on the relevance of the modeled dynamics. The 'precipiton' method consists in routing elementary water volumes (i.e. precipitons) on top of topography with erosive and deposition actions. The basic method assumes that precipitons move down the steepest descent slope of topography, which is a very crude approximation of the river hydrodynamics. Here we present an original way to calculate both river depth and velocity, from a method that remains intimately embedded into the precipiton framework. The method consists in solving water depth from a differential equation where the water depth is increased by a constant (small) quantity at each precipiton passage, and decreased by a mass balance 1st-order differential equation, where the flux is related to water depth from a Manning-type flow resistance equation. The precipiton are then routed on top of the water surface so calculated, towards lowest zones. The method is applicable even if the precipitons are routed one by one, i.e. independently of each others. It is not subject to the classical drying-wetting issue. The method has been applied to a large number of geomorphic cases including lake filling, circular channels, flow over topographic bumps, flow over vegetation patches and river banks, dam gate, or real cases with high resolution LIDAR topography. In all cases, the method is very fast to find a solution for water depths, which fits the shallow water solution without inertia. For real topographies, the

  12. Elastic models of the fast traps of carnivorous Dionaea and Aldrovanda

    Science.gov (United States)

    Joyeux, Marc

    2013-09-01

    The carnivorous aquatic waterwheel plant (Aldrovanda vesiculosa L.) and the closely related terrestrial Venus flytrap (Dionaea muscipula Sol. ex J. Ellis) both feature elaborate snap-traps, which shut after reception of an external mechanical stimulus by prey animals. Although Aldrovanda is usually considered a miniature aquatic Dionaea, the shutting mechanisms of the two plants differ quite markedly. The fast shutting of Aldrovanda is indeed based on a simple swelling or shrinking mechanism, while the movement of Dionaea's traps is accelerated by the snap-buckling of the lobes. The purpose of this Brief Report is to describe several key improvements to the elastic models that have recently been introduced to elucidate these movements [Poppinga and Joyeux, Phys. Rev. EPLEEE81063-651X10.1103/PhysRevE.84.041928 84, 041928 (2011)]. In particular, a precise mechanism for the action of the motor cells of Aldrovanda is proposed, the facts that the opening of the leaves of Dionaea is an irreversible mechanism based on growth and that the strain field is anisotropic and much smaller on the inner than on the outer surface of the leaves during shutting are taken properly into account, and a more accurate formula for calculating mean curvatures is used. The improvements brought to the model are described in detail and the physical consequences of these improvements are discussed.

  13. Fast Atmosphere-Ocean Model Runs with Large Changes in CO2

    Science.gov (United States)

    Russell, Gary L.; Lacis, Andrew A.; Rind, David H.; Colose, Christopher; Opstbaum, Roger F.

    2013-01-01

    How does climate sensitivity vary with the magnitude of climate forcing? This question was investigated with the use of a modified coupled atmosphere-ocean model, whose stability was improved so that the model would accommodate large radiative forcings yet be fast enough to reach rapid equilibrium. Experiments were performed in which atmospheric CO2 was multiplied by powers of 2, from 1/64 to 256 times the 1950 value. From 8 to 32 times, the 1950 CO2, climate sensitivity for doubling CO2 reaches 8 C due to increases in water vapor absorption and cloud top height and to reductions in low level cloud cover. As CO2 amount increases further, sensitivity drops as cloud cover and planetary albedo stabilize. No water vapor-induced runaway greenhouse caused by increased CO2 was found for the range of CO2 examined. With CO2 at or below 1/8 of the 1950 value, runaway sea ice does occur as the planet cascades to a snowball Earth climate with fully ice covered oceans and global mean surface temperatures near 30 C.

  14. A statistical model of uplink inter-cell interference with slow and fast power control mechanisms

    KAUST Repository

    Tabassum, Hina

    2013-09-01

    Uplink power control is in essence an interference mitigation technique that aims at minimizing the inter-cell interference (ICI) in cellular networks by reducing the transmit power levels of the mobile users while maintaining their target received signal quality levels at base stations. Power control mechanisms directly impact the interference dynamics and, thus, affect the overall achievable capacity and consumed power in cellular networks. Due to the stochastic nature of wireless channels and mobile users\\' locations, it is important to derive theoretical models for ICI that can capture the impact of design alternatives related to power control mechanisms. To this end, we derive and verify a novel statistical model for uplink ICI in Generalized-K composite fading environments as a function of various slow and fast power control mechanisms. The derived expressions are then utilized to quantify numerically key network performance metrics that include average resource fairness, average reduction in power consumption, and ergodic capacity. The accuracy of the derived expressions is validated via Monte-Carlo simulations. Results are generated for multiple network scenarios, and insights are extracted to assess various power control mechanisms as a function of system parameters. © 1972-2012 IEEE.

  15. A Unified Model for Repeating and Non-repeating Fast Radio Bursts

    Science.gov (United States)

    Bagchi, Manjari

    2017-04-01

    The model that fast radio bursts (FRBs) are caused by plunges of asteroids onto neutron stars can explain both repeating and non-repeating bursts. If a neutron star passes through an asteroid belt around another star, there would be a series of bursts caused by a series of asteroid impacts. Moreover, the neutron star would cross the same belt repetitively if it were in a binary with the star hosting the asteroid belt, leading to a repeated series of bursts. I explore the properties of neutron star binaries that could lead to the only known repeating FRB so far (FRB121102). In this model, the next two epochs of bursts are expected around 2017 February 27 and 2017 December 18. On the other hand, if the asteroid belt is located around the neutron star itself, then a chance fall of an asteroid from that belt onto the neutron star would lead to a non-repeating burst. Even a neutron star grazing an asteroid belt can lead to a non-repeating burst caused by just one asteroid plunge during the grazing. This is possible even when the neutron star is in a binary with the asteroid-hosting star, if the belt and the neutron star orbit are non-coplanar.

  16. Uncertainty quantification of fast sodium current steady-state inactivation for multi-scale models of cardiac electrophysiology.

    Science.gov (United States)

    Pathmanathan, Pras; Shotwell, Matthew S; Gavaghan, David J; Cordeiro, Jonathan M; Gray, Richard A

    2015-01-01

    Perhaps the most mature area of multi-scale systems biology is the modelling of the heart. Current models are grounded in over fifty years of research in the development of biophysically detailed models of the electrophysiology (EP) of cardiac cells, but one aspect which is inadequately addressed is the incorporation of uncertainty and physiological variability. Uncertainty quantification (UQ) is the identification and characterisation of the uncertainty in model parameters derived from experimental data, and the computation of the resultant uncertainty in model outputs. It is a necessary tool for establishing the credibility of computational models, and will likely be expected of EP models for future safety-critical clinical applications. The focus of this paper is formal UQ of one major sub-component of cardiac EP models, the steady-state inactivation of the fast sodium current, INa. To better capture average behaviour and quantify variability across cells, we have applied for the first time an 'individual-based' statistical methodology to assess voltage clamp data. Advantages of this approach over a more traditional 'population-averaged' approach are highlighted. The method was used to characterise variability amongst cells isolated from canine epi and endocardium, and this variability was then 'propagated forward' through a canine model to determine the resultant uncertainty in model predictions at different scales, such as of upstroke velocity and spiral wave dynamics. Statistically significant differences between epi and endocardial cells (greater half-inactivation and less steep slope of steady state inactivation curve for endo) was observed, and the forward propagation revealed a lack of robustness of the model to underlying variability, but also surprising robustness to variability at the tissue scale. Overall, the methodology can be used to: (i) better analyse voltage clamp data; (ii) characterise underlying population variability; (iii) investigate

  17. Fasting cycles potentiate the efficacy of gemcitabine treatment in in vitro and in vivo pancreatic cancer models

    Science.gov (United States)

    Mazza, Tommaso; Panebianco, Concetta; Saracino, Chiara; Pereira, Stephen P.; Graziano, Paolo; Pazienza, Valerio

    2015-01-01

    Background/aims Pancreatic cancer (PC) is ranked as the fourth leading cause of cancer-related deaths worldwide. Despite recent advances in treatment options, a modest impact on the outcome of the disease is observed so far. Short-term fasting cycles have been shown to potentiate the efficacy of chemotherapy against glioma. The aim of this study was to assess the effect of fasting cycles on the efficacy of gemcitabine, a standard treatment for PC patients, in vitro and in an in vivo pancreatic cancer mouse xenograft model. Materials and Methods BxPC-3, MiaPaca-2 and Panc-1 cells were cultured in standard and fasting mimicking culturing condition to evaluate the effects of gemcitabine. Pancreatic cancer xenograft mice were subjected to 24h starvation prior to gemcitabine injection to assess the tumor volume and weight as compared to mice fed ad libitum. Results Fasted pancreatic cancer cells showed increased levels of equilibrative nucleoside transporter (hENT1), the transporter of gemcitabine across the cell membrane, and decreased ribonucleotide reductase M1 (RRM1) levels as compared to those cultured in standard medium. Gemcitabine was more effective in inducing cell death on fasted cells as compared to controls. Consistently, xenograft pancreatic cancer mice subjected to fasting cycles prior to gemcitabine injection displayed a decrease of more than 40% in tumor growth. Conclusion Fasting cycles enhance gemcitabine effect in vitro and in the in vivo PC xenograft mouse model. These results suggest that restrictive dietary interventions could enhance the efficacy of existing cancer treatments in pancreatic cancer patients. PMID:26176887

  18. Development and Characterization of Carbon-Fiber Microbiosensors for Fast-Scan Cyclic Voltammetry

    Science.gov (United States)

    Lugo-Morales, Leyda Zoraida

    Electrochemistry has been shown to be a robust tool in neuroscience. The use of carbon-fiber microelectrodes coupled with background-subtracted fast-scan cyclic voltammetry (FSCV) offers high sensitivity, selectivity, as well as the spatial and temporal resolution necessary for monitoring rapid fluctuations of electroactive molecules in live brain tissue. Dopamine (DA) is a neurotransmitter playing a key role in the regulation of reward and motivated behavior. FSCV has been used to understand DA dynamics and how these underlie discrete aspects of brain function. The methodological aspects of real-time DA detection at carbon-fiber microelectrodes using FSCV in anesthetized and awake animals are presented. Furthermore, the combination of FSCV with other neuroanalytical techniques is also explained. The advantages of FSCV and carbon-fiber microelectrodes can be expanded to the detection of non-electroactive analytes. This broadens the scope of FSCV such that it can be used to investigate how changes in non-electroactive chemicals underlie disease, cognition, and behavior. Carbon-fiber microelectrodes can be modified with an enzyme to monitor non-electroactive molecules, generating an electroactive product (usually hydrogen peroxide, H2O2). The first voltammetric detection of H2O 2 at bare carbon-fiber microelectrodes using FSCV has recently been reported. Thus, an avenue exists to utilize FSCV at enzyme-modified microelectrodes to voltammetrically identify and quantify non-electroactive analytes in real-time. Such an approach will overcome many limitations associated with the traditional amperometric detection scheme, which lacks electrochemical selectivity. Electrodeposition of the biopolymer chitosan with glucose oxidase (GOx) at the carbon surface yields a stable, sensitive, and selective glucose microbiosensor that has been utilized to detect glucose fluctuations in vivo with unprecedented speed. This new method has revealed the first rapid glucose fluctuations in

  19. Study of Higgs bosons in the WW final state and development of a fast calorimeter simulation for the ATLAS experiment

    CERN Document Server

    Duehrssen, Michael

    2009-01-01

    Monte Carlo simulations of physics events, including the detailed simulation of the detector, are an indispensable tool in the development and implementation of analysis strategies for high energy physics experiments. Despite massive worldwide computing resources, it is expected that only the equivalent of a few percent of the recorded ATLAS data can be simulated with the full ATLAS detector simulation, while most analyses require significantly more Monte Carlo events than data events for signal and important background processes. In the course of this thesis the fast calorimeter simulation FastCaloSim was developed that is combined in the Atlfast-II detector simulation package with full simulations of the other detector components. Atlfast-II reduces the event simulation time by a factor of 10-20 without severely compromising the simulation quality of critical variables. During the last two years, Atlfast-II was validated by the ATLAS collaboration and used to simulate several hundred million events, many of...

  20. Development of an x-ray Talbot-Lau moire deflectometer for fast density profile measurements of dense plasmas generated by beam-target interactions

    Energy Technology Data Exchange (ETDEWEB)

    Clayton, Dan [National Security Technol., LLC, Los Alamos, NM (United States); Berninger, M; Meidinger, A; Stutman, Dan; Valdivia, Maria Pia

    2015-05-01

    For the first time an x-ray Talbot-Lau moire deflectometer is being developed that will use a flash tube source and fast detector for dynamic density gradient measurements. In Talbot-Lau moire deflectometry, an x-ray grating makes an image of itself on a second grating (the Talbot effect) to produce a moire pattern on a detector. The test object is placed between these gratings, with variations in index of refraction changing the pattern. A third grating in front of an incoherent x-ray source produces an array of coherent sources. With a 150 kV x-ray flash tube as the source, the gratings are placed in a glancing angle setup for performance at ~60 keV. The detector is a gated CCD with a fast scintillator for x-ray conversion. This diagnostic, designed for the Dual-Axis Radiographic Hydrodynamic Test facility (DARHT) at Los Alamos National Laboratory, measures the density profile of dense plasma plumes ejected from beam-target interactions. DARHT has two high-current, pulsed, inductive linear electron accelerators with bremsstrahlung targets at the end of each beam line to create 2-D radiographic images of hydrodynamic tests. One multi-pulse accelerator has up to four beam pulses striking the same target within 2 μs. Computer simulations that model target evolution and ejected material between pulses are used to design these targets for optimal radiographic performance; the x-ray deflectometer will directly measure density gradients in the ejected plumes and provide the first experimental constraints to these models. During the first year, currently underway, the diagnostic systems are being designed. In year two, the flash tube and fast detector will be deployed at DARHT for radiographic imaging while the deflectometer is built and tested on the bench with a continuous source. Finally, in year three, the fast deflectometer will be installed on DARHT and density measurements will be performed.

  1. Slow and Fast Neocortical Oscillations in the Senescence-Accelerated Mouse Model SAMP8

    Directory of Open Access Journals (Sweden)

    Patricia Castano-Prat

    2017-05-01

    Full Text Available The senescence-accelerated mouse prone 8 (SAMP8 model is characterized by accelerated, progressive cognitive decline as well as Alzheimer’s disease (AD-like neurodegenerative changes, and resembles the etiology of multicausal, sporadic late-onset/age-related AD in humans. Our aim was to find whether these AD-like pathological features, together with the cognitive deficits present in the SAMP8 strain, are accompanied by disturbances in cortical network activity with respect to control mice (SAM resistance 1, SAMR1 and, if so, how the alterations in cortical activity progress with age. For this purpose, we characterized the extracellular spontaneous oscillatory activity in different regions of the cerebral cortex of SAMP8 and SAMR1 mice under ketamine anesthesia at 5 and 7 months of age. Under these conditions, slow oscillations and fast rhythms generated in the cortical network were recorded and different parameters of these oscillations were quantified and compared between SAMP8 and their control, SAMR1 mice. The average frequency of slow oscillations in SAMP8 mice was decreased with respect to the control mice at both studied ages. An elongation of the silent periods or Down states was behind the decreased slow oscillatory frequency while the duration of active or Up states remained stable. SAMP8 mice also presented increased cycle variability and reduced high frequency components during Down states. During Up states, the power peak in the gamma range was displaced towards lower frequencies in all the cortical areas of SAMP8 with respect to control mice suggesting that the spectral profile of SAMP8 animals is shifted towards lower frequencies. This shift is reminiscent to one of the principal hallmarks of electroencephalography (EEG abnormalities in patients with Alzheimer’s disease, and adds evidence in support of the suitability of the SAMP8 mouse as a model of this disease. Although some of the differences between SAMP8 and control mice

  2. Development of numerical simulation system for thermal-hydraulic analysis in fuel assembly of sodium-cooled fast reactor

    Science.gov (United States)

    Ohshima, Hiroyuki; Uwaba, Tomoyuki; Hashimoto, Akihiko; Imai, Yasutomo; Ito, Masahiro

    2015-12-01

    A numerical simulation system, which consists of a deformation analysis program and three kinds of thermal-hydraulics analysis programs, is being developed in Japan Atomic Energy Agency in order to offer methodologies to clarify thermal-hydraulic phenomena in fuel assemblies of sodium-cooled fast reactors under various operating conditions. This paper gives the outline of the system and its applications to fuel assembly analyses as a validation study.

  3. Development of numerical simulation system for thermal-hydraulic analysis in fuel assembly of sodium-cooled fast reactor

    Energy Technology Data Exchange (ETDEWEB)

    Ohshima, Hiroyuki; Uwaba, Tomoyuki [Japan Atomic Energy Agency (4002 Narita, O-arai, Ibaraki 311-1393, Japan) (Japan); Hashimoto, Akihiko; Imai, Yasutomo [NDD Corporation (1-1-6 Jounan, Mito, Ibaraki 310-0803, Japan) (Japan); Ito, Masahiro [NESI Inc. (4002 Narita, O-arai, Ibaraki 311-1393, Japan) (Japan)

    2015-12-31

    A numerical simulation system, which consists of a deformation analysis program and three kinds of thermal-hydraulics analysis programs, is being developed in Japan Atomic Energy Agency in order to offer methodologies to clarify thermal-hydraulic phenomena in fuel assemblies of sodium-cooled fast reactors under various operating conditions. This paper gives the outline of the system and its applications to fuel assembly analyses as a validation study.

  4. Development of fast neutron radiography system based on portable neutron generator

    Energy Technology Data Exchange (ETDEWEB)

    Yi, Chia Jia, E-mail: gei-i-kani@hotmail.com; Nilsuwankosit, Sunchai, E-mail: sunchai.n@chula.ac.th [Department of Nuclear Engineering, Faculty of Engineering, Chulalongkorn University, Phayathai Rd., Patumwan, Bangkok, THAILAND 10330 (Thailand)

    2016-01-22

    Due to the high installation cost, the safety concern and the immobility of the research reactors, the neutron radiography system based on portable neutron generator is proposed. Since the neutrons generated from a portable neutron generator are mostly the fast neutrons, the system is emphasized on using the fast neutrons for the purpose of conducting the radiography. In order to suppress the influence of X-ray produced by the neutron generator, a combination of a shielding material sandwiched between two identical imaging plates is used. A binary XOR operation is then applied for combining the information from the imaging plates. The raw images obtained confirm that the X-ray really has a large effect and that XOR operation can help enhance the effect of the neutrons.

  5. Development of fast neutron radiography system based on portable neutron generator

    Science.gov (United States)

    Yi, Chia Jia; Nilsuwankosit, Sunchai

    2016-01-01

    Due to the high installation cost, the safety concern and the immobility of the research reactors, the neutron radiography system based on portable neutron generator is proposed. Since the neutrons generated from a portable neutron generator are mostly the fast neutrons, the system is emphasized on using the fast neutrons for the purpose of conducting the radiography. In order to suppress the influence of X-ray produced by the neutron generator, a combination of a shielding material sandwiched between two identical imaging plates is used. A binary XOR operation is then applied for combining the information from the imaging plates. The raw images obtained confirm that the X-ray really has a large effect and that XOR operation can help enhance the effect of the neutrons.

  6. A preliminary report on the development of MATLAB tensor classes for fast algorithm prototyping.

    Energy Technology Data Exchange (ETDEWEB)

    Bader, Brett William; Kolda, Tamara Gibson (Sandia National Laboratories, Livermore, CA)

    2004-07-01

    We describe three MATLAB classes for manipulating tensors in order to allow fast algorithm prototyping. A tensor is a multidimensional or N-way array. We present a tensor class for manipulating tensors which allows for tensor multiplication and 'matricization.' We have further added two classes for representing tensors in decomposed format: cp{_}tensor and tucker{_}tensor. We demonstrate the use of these classes by implementing several algorithms that have appeared in the literature.

  7. Development of a rapid screening technique for organochlorine pesticides using solvent microextraction (SME) and fast gas chromatography (GC).

    Science.gov (United States)

    de Jager, L S; Andrews, A R

    2000-11-01

    A novel, fast screening method for organochlorine pesticides (OCPs) in water samples has been developed. Total analysis time was less than 9 min, allowing 11 samples to be screened per hour. The relatively new technique of solvent microextraction (SME) was used to extract and preconcentrate the pesticides into a single drop of hexane. The use of a conventional carbon dioxide cryotrap was investigated for introduction of the extract onto a micro-bore (0.1 mm) capillary column for fast GC analysis. A pulsed-discharge electron capture detector was used which yielded selective and sensitive measurement of the pesticide peaks. Fast GC conditions were optimised and tested with the previously developed SME procedure. Calibration curves yielded good linearity and concentrations down to 0.25 ng mL-1 were detectable with RSD values ranging from 12.0 to 28% and LOD for most OCPs at 0.25 ng mL-1. Spiked river water samples were tested and using the developed screen we were able to differentiate between spiked samples and samples containing no OCPs.

  8. Development of bio-fuel from palm frond via fast pyrolysis

    Science.gov (United States)

    Solikhah, M. D.; Raksodewanto, A. A.; Kismanto, A.; Karuana, F.; Heryana, Y.; Riza; Pratiwi, F. T.

    2017-05-01

    In order to fulfill the fuel demand in the future, Indonesia has to find a sustainable alternative for its energy. Energy source in the form of biomass is a promising alternative since its availability is abundance in this tropical country. Biomass can be converted into liquid fuel via fast pyrolysis by contacting the solid biomass into hot medium in the absence of oxygen. Hot sand is the common heat carrier for fast pyrolysis purposes but it is very abrasive and required high pyrolysis temperature (450-600 °C). This paper will discuss on the equipment design and experiment of fast pyrolysis of palm frond using high boiling point thermal oil as heat carrier. Experiments show that by using thermal oil as heat carrier, bio-oil can be produced at lower pyrolysis temperature of 350 °C, compared to the one using hot sand as heating carrier. The yield of bio-oil production is 36.4 % of biomass feeding. The water content of bio-oil is 52.77 % mass while heating value is 10.25 MJ/kg.

  9. Development and in vitro evaluation of fast-dissolving oral films of ondansetron hydrochloride

    Directory of Open Access Journals (Sweden)

    Shohreh Alipour

    2015-03-01

    Full Text Available Ondansetron hydrochloride, a selective 5-HT3 receptor blocker, is an effective antiemetic drug with oral bioavailability of 60% and half-life of 4-5 hours. The present study was carried out to prepare fast dissolving films of ondansetron hydrochloride to increase patient compliance and improve efficacy of this drug. Films were prepared by solvent casting method, using poly vinyl alcohol, poly vinyl pyrrolidone and konjac glucomannan as film formers and PEG400 as plasticizer. Natural and synthetic sweeteners were used for masking bitterness of the drug. Satisfactory results were obtained from evaluation of physical characteristics of fast dissolving films of ondansetron hydrochloride including: thickness (0.37-0.39 mm, surface pH (6.77, folding endurance (up to 300 times and tensile strength (35.75-50.93 g/cm². Films were also subjected to an in vitro dissolution and release studies. In vitro drug release studies indicated 93-95% release in 5 min. Fast dissolving films of ondansetron could be a potential alternative for the currently marketed oral formulation, parenteral form and suppository with better patient compliance and higher bioavailability for the rapid control of emesis.

  10. A fast 3D surface reconstruction and volume estimation method for grain storage based on priori model

    Science.gov (United States)

    Liang, Xian-hua; Sun, Wei-dong

    2011-06-01

    Inventory checking is one of the most significant parts for grain reserves, and plays a very important role on the macro-control of food and food security. Simple, fast and accurate method to obtain internal structure information and further to estimate the volume of the grain storage is needed. Here in our developed system, a special designed multi-site laser scanning system is used to acquire the range data clouds of the internal structure of the grain storage. However, due to the seriously uneven distribution of the range data, this data should firstly be preprocessed by an adaptive re-sampling method to reduce the data redundancy as well as noise. Then the range data is segmented and useful features, such as plane and cylinder information, are extracted. With these features a coarse registration between all of these single-site range data is done, and then an Iterative Closest Point (ICP) algorithm is carried out to achieve fine registration. Taking advantage of the structure of the grain storage being well defined and the types of them are limited, a fast automatic registration method based on the priori model is proposed to register the multi-sites range data more efficiently. Then after the integration of the multi-sites range data, the grain surface is finally reconstructed by a delaunay based algorithm and the grain volume is estimated by a numerical integration method. This proposed new method has been applied to two common types of grain storage, and experimental results shown this method is more effective and accurate, and it can also avoids the cumulative effect of errors when registering the overlapped area pair-wisely.

  11. Double-sigmoid model for fitting fatigue profiles in mouse fast- and slow-twitch muscle.

    Science.gov (United States)

    Cairns, S P; Robinson, D M; Loiselle, D S

    2008-07-01

    We present a curve-fitting approach that permits quantitative comparisons of fatigue profiles obtained with different stimulation protocols in isolated slow-twitch soleus and fast-twitch extensor digitorum longus (EDL) muscles of mice. Profiles from our usual stimulation protocol (125 Hz for 500 ms, evoked once every second for 100-300 s) could be fitted by single-term functions (sigmoids or exponentials) but not by a double exponential. A clearly superior fit, as confirmed by the Akaiki Information Criterion, was achieved using a double-sigmoid function. Fitting accuracy was exceptional; mean square errors were typically 0.9995. The first sigmoid (early fatigue) involved approximately 10% decline of isometric force to an intermediate plateau in both muscle types; the second sigmoid (late fatigue) involved a reduction of force to a final plateau, the decline being 83% of initial force in EDL and 63% of initial force in soleus. The maximal slope of each sigmoid was seven- to eightfold greater in EDL than in soleus. The general applicability of the model was tested by fitting profiles with a severe force loss arising from repeated tetanic stimulation evoked at different frequencies or rest periods, or with excitation via nerve terminals in soleus. Late fatigue, which was absent at 30 Hz, occurred earlier and to a greater extent at 125 than 50 Hz. The model captured small changes in rate of late fatigue for nerve terminal versus sarcolemmal stimulation. We conclude that a double-sigmoid expression is a useful and accurate model to characterize fatigue in isolated muscle preparations.

  12. Development of a dual phantom technique for measuring the fast neutron component of dose in boron neutron capture therapy

    Energy Technology Data Exchange (ETDEWEB)

    Sakurai, Yoshinori, E-mail: yosakura@rri.kyoto-u.ac.jp; Tanaka, Hiroki; Kondo, Natsuko; Kinashi, Yuko; Suzuki, Minoru; Masunaga, Shinichiro; Ono, Koji; Maruhashi, Akira [Kyoto University Research Reactor Institute, Asashironishi 2-1010, Kumatori-cho, Sennan-gun, Osaka 590-0494 (Japan)

    2015-11-15

    Purpose: Research and development of various accelerator-based irradiation systems for boron neutron capture therapy (BNCT) is underway throughout the world. Many of these systems are nearing or have started clinical trials. Before the start of treatment with BNCT, the relative biological effectiveness (RBE) for the fast neutrons (over 10 keV) incident to the irradiation field must be estimated. Measurements of RBE are typically performed by biological experiments with a phantom. Although the dose deposition due to secondary gamma rays is dominant, the relative contributions of thermal neutrons (below 0.5 eV) and fast neutrons are virtually equivalent under typical irradiation conditions in a water and/or acrylic phantom. Uniform contributions to the dose deposited from thermal and fast neutrons are based in part on relatively inaccurate dose information for fast neutrons. This study sought to improve the accuracy in the dose estimation for fast neutrons by using two phantoms made of different materials in which the dose components can be separated according to differences in the interaction cross sections. The development of a “dual phantom technique” for measuring the fast neutron component of dose is reported. Methods: One phantom was filled with pure water. The other phantom was filled with a water solution of lithium hydroxide (LiOH) capitalizing on the absorbing characteristics of lithium-6 (Li-6) for thermal neutrons. Monte Carlo simulations were used to determine the ideal mixing ratio of Li-6 in LiOH solution. Changes in the depth dose distributions for each respective dose component along the central beam axis were used to assess the LiOH concentration at the 0, 0.001, 0.01, 0.1, 1, and 10 wt. % levels. Simulations were also performed with the phantom filled with 10 wt. % {sup 6}LiOH solution for 95%-enriched Li-6. A phantom was constructed containing 10 wt. % {sup 6}LiOH solution based on the simulation results. Experimental characterization of the

  13. Development Model for Research Infrastructures

    Science.gov (United States)

    Wächter, Joachim; Hammitzsch, Martin; Kerschke, Dorit; Lauterjung, Jörn

    2015-04-01

    . The maturity of individual scientific domains differs considerably. • Technologically and organisationally many different RI components have to be integrated. Individual systems are often complex and have a long-term history. Existing approaches are on different maturity levels, e.g. in relation to the standardisation of interfaces. • The concrete implementation process consists of independent and often parallel development activities. In many cases no detailed architectural blue-print for the envisioned system exists. • Most of the funding currently available for RI implementation is provided on a project basis. To increase the synergies in infrastructure development the authors propose a specific RI Maturity Model (RIMM) that is specifically qualified for open system-of-system environments. RIMM is based on the concepts of Capability Maturity Models for organisational development, concretely the Levels of Conceptual Interoperability Model (LCIM) specifying the technical, syntactical, semantic, pragmatic, dynamic, and conceptual layers of interoperation [1]. The model is complemented by the identification and integration of growth factors (according to the Nolan Stages Theory [2]). These factors include supply and demand factors. Supply factors comprise available resources, e.g., data, services and IT-management capabilities including organisations and IT-personal. Demand factors are the overall application portfolio for RIs but also the skills and requirements of scientists and communities using the infrastructure. RIMM thus enables a balanced development process of RI and RI components by evaluating the status of the supply and demand factors in relation to specific levels of interoperability. [1] Tolk, A., Diallo, A., Turnitsa, C. (2007): Applying the Levels of Conceptual Interoperability Model in Support of Integratability, Interoperability, and Composability for System-of-Systems Engineering. Systemics, Cybernetics and Informatics, Volume 5 - Number 5. [2

  14. Recent development of hydrodynamic modeling

    Science.gov (United States)

    Hiran